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<a href="/" class="footerLink"><font color="red">BBS List</font></a> | <a href="faq.php" class="footerLink">FAQ</a> | <a href="/api" class="footerLink">API</a><br /><!-- Main content start -->
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<BR>
<table class='bbs'><tr><td class='bbss' bgcolor='#66cc66'><b>101 Boards Online:</b></td></tr></table><br> <table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">13th Floor BBS (The Original)</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Hoy Brothers</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">13th.hoyvision.com</td>
<td rowspan="8" class="bbsi"><a href="images/2018-9-21-22-35-51-13thfloorcd.jpg" target="_blank"><img width="165" src="images/2018-9-21-22-35-51-13thfloorcd.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image v3.0 [HVI Mod]</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64 Breadbin - Lt. Kernal - SwiftLink 38.4k - Turbo Chameleon</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">hoyvision.com</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Nashville, TN</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 5, 2021, 7:22 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">UDs, active networked message bases, custom scripts, online doors, content back to the 80s</td>
<td class="bbse"><a href="editbbs.php?bbs_id=120" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">1st Wrong Number ][</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Bucko, X-Tec</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cib.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/1stwrongnumber.jpg" target="_blank"><img width="165" src="images/1stwrongnumber.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6404</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2b (With telnet enhancements)</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">64C, Thunderdrive, Firedrive, </td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lakeland, FL</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 9, 2021, 2:41 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">The original WN2 from 1994 back online. PFiles, MFiles, TFiles, Large UD Library</td>
<td class="bbse"><a href="editbbs.php?bbs_id=89" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">2nd Wrong Number ][</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Bucko, X-Tec</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cib.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/2ndwrongnumber.jpg" target="_blank"><img width="165" src="images/2ndwrongnumber.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6405</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 2.0 R3.1</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Dual Thunderdrive SX64, BBS Server</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lakeland Florida</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 3, 2019, 5:22 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">The ONLY Image 2.0 system in operation.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=90" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">64 Vintage Remix</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">XxSwitchBladexX</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">64vintageremixbbs.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/64vintageremix.jpg" target="_blank"><img width="165" src="images/64vintageremix.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 v8.0 / Modded Vice-Emulation W/TCPSER</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">ThinClient WYSE-MiniDesktop 10gig-HD 512Ram 800MHZ.</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.digitaldial.us" target="_blank" class="blueLink">http://www.digitaldial.us</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Miami, Florida</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 21, 2023, 7:50 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Chatserver up 24/7 @ via web-browser http://www.digitaldial.us/fterm/digitaldial.html</td>
<td class="bbse"><a href="editbbs.php?bbs_id=16" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">68K Time Machine BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Midnight Flip</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">68ktm.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/2023-9-30-14-59-59-68ktm.jpg" target="_blank"><img width="165" src="images/2023-9-30-14-59-59-68ktm.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">1024</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">MAXsBBS v1.54</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Emulated Amiga</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">South Australia</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 22, 2022, 5:24 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Support for Amiga, Commodore 64, and anything else retro.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=181" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">8-Bit Playground</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Hoy Brothers</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">8bit.hoyvision.com</td>
<td rowspan="8" class="bbsi"><a href="images/2020-1-15-2-39-10-8bit.png" target="_blank"><img width="165" src="images/2020-1-15-2-39-10-8bit.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Net 64 DS2 v2.5 +HVImod, running at 38.4k baud!</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Ultimate64 - CMD-HD - Turbo232 - LOTSA mods & custom graphics</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.hoyvision.com" target="_blank" class="blueLink">http://www.hoyvision.com</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Antioch, TN</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 21, 2022, 2:33 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Quite possibly the largest collection of online games of any DS-2 BBS, heavily customized, regularly updated. HVI-Mod HQ</td>
<td class="bbse"><a href="editbbs.php?bbs_id=148" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">A Java Zone</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">dr coomer</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">2.tcp.ngrok.io</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">17595</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Java</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Windows Server</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://bbs-connect.techstuffstuff.repl.co</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">https://bbs-connect.techstuffstuff.repl.co</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">N / A</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 17, 2021, 6:52 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Run help for a list of commands! ALSO Connect with this!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=163" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Altar Of Wares</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Trouble/Onslaught</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">altarofwaresbbs.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/2023-9-30-15-2-34-aow.ad.png" target="_blank"><img width="165" src="images/2023-9-30-15-2-34-aow.ad.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6464</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">MosesModded C*Base</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 128 CMD-HD 4 Gigs JiffyDos RS232Clone with Cable running to Windows 10 Pc running BBS Server 38400 Baud</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Philadelphia, PA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">May 9, 2022, 4:09 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Onslaught Support!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=179" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Amiga City</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">MarisaG</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">amigacity.xyz</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Synchronet</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commercial Hosting Provider</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://AmigaCity.xyz</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">South San Francisco, CA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 23, 2018, 7:00 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Dedicated to the Commodore Amiga, overy 2,600 file downloads and over 100 door games!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=109" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Anarchy Underground</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Chris537</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">aubbs.zapto.org or aubbs.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/screenshotanarchy.jpg" target="_blank"><img width="165" src="images/screenshotanarchy.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">2300</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Base 3.3.6 Tao/Triad Version</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">100% Commodore Breadbin C64 w/JD with the Thunder Drive 4.1gb, Real Swiftlink@9600bps, 1.4ghz pc 512meg mem, for TelnetBridge.</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">S.W. Cincinnati, Ohio</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 14, 2022, 2:34 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">20 Message Bases, 25 UD Bases, Alot of Warez, Utilities, & Demos (Many Blocks!!!!) Online Since 11/29/09</td>
<td class="bbse"><a href="editbbs.php?bbs_id=44" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Antidote</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Taper</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">antidote.triad.se</td>
<td rowspan="8" class="bbsi"><a href="images/antidote.jpg" target="_blank"><img width="165" src="images/antidote.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C*Base (http://www.acc.umu.se/~tao/cbase/)</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.triad.se/" target="_blank" class="blueLink">http://www.triad.se/</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Bjuv, Sweden</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 28, 2021, 10:51 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=6" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Atlantis BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Darkstar</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">atl.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/2023-9-30-15-4-47-atlantis.jpg" target="_blank"><img width="165" src="images/2023-9-30-15-4-47-atlantis.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6401</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 3.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 64, RA Thunderdrive, uIEC/SD, 1541, 38400bps</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Atlanta, Georgia</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 13, 2022, 6:07 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Come join the Retro Experience again!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=110" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Avalon Isle</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Darkstar</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">atl.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 3.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 64, uIEC/SDcard, 1541, 38400bps</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Atlanta, Georgia</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 14, 2022, 8:00 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=83" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Bayou BBS </td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Jazzy J</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">jayctheriot.com</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6401</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">New Image v. 3.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">VICE, Dell R420 Server</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Houma, Louisiana</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">June 29, 2022, 4:10 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Totally Virtualized in a Manjaro QEMU/KVM on Ubuntu 20.04 Dell R420 server.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=103" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Bayou Petit Caillou BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Jazzy J</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bay.jayscafe.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6402</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">New Image v. 3.0 </td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">VICE, Dell R420</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">to be reestablished</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Houma, Louisiana</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 22, 2022, 4:44 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Fully virtualized on a KVM/QEMU vm hosted by Ubuntu 20.04 on a Dell R420 Server</td>
<td class="bbse"><a href="editbbs.php?bbs_id=134" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">BBS Drean C64</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Ezequiel Filgueiras</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbsdreanc64.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/bbs-drean.png" target="_blank"><img width="165" src="images/bbs-drean.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">10000</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">RetroBBS TURBO56K</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Linux PC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lanus, Argentina</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 20, 2021, 4:24 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Multimedia BBS, requires Retroterm to connect</td>
<td class="bbse"><a href="editbbs.php?bbs_id=169" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">BBS Retroacademy</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Francesco Sblendorio</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.retrocampus.com</td>
<td rowspan="8" class="bbsi"><a href="images/2019-2-23-17-24-12-screenshot-retro-academy.png" target="_blank"><img width="165" src="images/2019-2-23-17-24-12-screenshot-retro-academy.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6510</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Petscii BBS Builder: https://github.com/sblendorio/petscii-bbs/</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Virtual amd64 server with Debian Linux</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://www.retroacademy.it</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">United Kingdom</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 21, 2023, 9:52 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Language: Italian </td>
<td class="bbse"><a href="editbbs.php?bbs_id=133" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Boars Head Tavern </td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Macx</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">byob.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/boarshead.png" target="_blank"><img width="165" src="images/boarshead.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C*Base</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64, SilverSurfer, SD2IEC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 23, 2021, 7:21 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=167" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Borderline</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Balzabaar</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">borderlinebbs.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/borderline.jpg" target="_blank"><img width="165" src="images/borderline.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">All American BBS v9.6</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64c with 6 floppy drives</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://borderlinebbs.dyndns.org" target="_blank" class="blueLink">http://borderlinebbs.dyndns.org</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://borderlinebbs.dyndns.org/blflashterm" target="_blank" class="blueLink">http://borderlinebbs.dyndns.org/blflashterm</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Hemet, California, U.S.A.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 3, 2020, 8:47 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Also accessible via DIAL-UP at 951-652-1690</td>
<td class="bbse"><a href="editbbs.php?bbs_id=19" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">CIA Amiga BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Tim Grooms</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">ciaamigabbs.dynu.net</td>
<td rowspan="8" class="bbsi"><a href="images/2023-9-30-14-48-30-ciaamiga.jpg" target="_blank"><img width="165" src="images/2023-9-30-14-48-30-ciaamiga.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Excelsior! Amiga</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Amiga 1200</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.ciaamiga.org" target="_blank" class="blueLink">http://www.ciaamiga.org</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Mayflower, AR</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 21, 2018, 5:06 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Telnet only, no dialup</td>
<td class="bbse"><a href="editbbs.php?bbs_id=117" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Citadel 64</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Chiefnerd</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">citadel64.thejlab.com</td>
<td rowspan="8" class="bbsi"><a href="images/citadel.jpg" target="_blank"><img width="165" src="images/citadel.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 v8</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64,uIEC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Oakdale, CA USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 1, 2019, 1:03 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Online as of 12/31/2018</td>
<td class="bbse"><a href="editbbs.php?bbs_id=40" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Cnet bbs</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Phillip Taylor</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cnetbbs.dynu.net</td>
<td rowspan="8" class="bbsi"><a href="images/cnet-bbs.png" target="_blank"><img width="165" src="images/cnet-bbs.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">1940</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Cnet Version 5.21</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Amiga</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Virginia</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 12, 2020, 4:27 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">The bbs supports the Amiga, Commodore 64/128 and the Commodore Pet. Online games, Files and a lot more.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=150" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Commodore Image 2</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">X-TEC</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cib.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/CommodoreImageBBS2.jpg" target="_blank"><img width="165" src="images/CommodoreImageBBS2.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6401</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2b, y2k, 19.2k baud</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C=64C, RA Hyperdrive, RA Thunderdrive, Link232</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lakeland, Florida</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 15, 2017, 10:06 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">A nostalgic look at a 1991 BBS complete with preserved National and San Diego area message bases from that era.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=69" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Commodore Image 3</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">X-TEC</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cib.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/CommodoreImageBBS3.jpg" target="_blank"><img width="165" src="images/CommodoreImageBBS3.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6402</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2b y2k compliant 19.2k baud</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">SuperSX-64, 2 Thunderdrives, JiffyDOS</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lakeland, Florida</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">March 3, 2015, 3:37 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Massive UD section, SID Music files, Image BBS Support, Networked Message Bases.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=72" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Commodore Image BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">X-TEC</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cib.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/CommodoreImageBBS.jpg" target="_blank"><img width="165" src="images/CommodoreImageBBS.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2b y2k compliant 19.2k baud</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C=64C, RA Hyperdrive, RA Thunderdrive, Link232</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lakeland, FL</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 2, 2017, 8:18 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">NISSA Network Node 1 (CIB) Now running NFL Football Bookie for the 2017-2018 season.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=66" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Connect 2400</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Tom Servo</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">https://connect2400.com</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">443</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Connect2400.com custom software</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Linux VPC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://connect2400.com</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Cedar Knolls NJ USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 14, 2023, 8:02 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">real-time chat system for all Commodore friends. Music and games too! Use any modern web browser.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=188" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Cottonwood</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Balzabaar</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cottonwoodbbs.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/cottonwood.jpg" target="_blank"><img width="165" src="images/cottonwood.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6502</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 v7.37</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 64c w/ Rear Admiral ThunderDrive (CMD HD clone - 4.1 GB)</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://cottonwoodbbs.dyndns.org" target="_blank" class="blueLink">http://cottonwoodbbs.dyndns.org</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://cottonwoodbbs.dyndns.org/flashterm" target="_blank" class="blueLink">http://cottonwoodbbs.dyndns.org/flashterm</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Hemet, California, U.S.A.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">June 24, 2017, 6:54 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Also accessible via DIAL-UP at 951-652-1690</td>
<td class="bbse"><a href="editbbs.php?bbs_id=20" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Dark Endless</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Trouble/Onslaught</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">darkendlessbbs.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/2023-9-30-15-1-48-de.ad.png" target="_blank"><img width="165" src="images/2023-9-30-15-1-48-de.ad.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6510</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">TaoModded C*Base 3.3.8</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Windows 10 HP Laptop Running TCPSer and Vice Emulator 3.6 with Virtual CMD 4gig HD and JiffyDos</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Philadelphia, PA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">May 9, 2022, 3:56 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">New World Order Hq</td>
<td class="bbse"><a href="editbbs.php?bbs_id=178" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">DARKLEVEL</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Knobby</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">darklevel.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/2020-1-28-18-51-8-darklevel.jpg" target="_blank"><img width="165" src="images/2020-1-28-18-51-8-darklevel.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">HolyMoses modded C*Base 3.1 with 57600 Baud</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64R MK2, SuperCPU, RAMlink, HD, Turbo232, SD2IEC w/ Wifi-SD</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Germany near Frankfurt</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">1-28-2020</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">ROLE EHQ</td>
<td class="bbse"><a href="editbbs.php?bbs_id=147" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">DeepSkies BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">RICK-T137</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.deepskies.com</td>
<td rowspan="8" class="bbsi"><a href="images/2023-9-30-14-46-36-ds.jpg" target="_blank"><img width="165" src="images/2023-9-30-14-46-36-ds.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 v8.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 64, SD2IEC, Strikelink WiFi Modem</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.deepskies.com" target="_blank" class="blueLink">http://www.deepskies.com</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Toronto, Canada</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 13, 2023, 3:19 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Now running at 9600 baud!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=186" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Digital Dial</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">XxSwitchBladexX</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">digitaldial.homeunix.com</td>
<td rowspan="8" class="bbsi"><a href="images/digitaldial.jpg" target="_blank"><img width="165" src="images/digitaldial.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">2300</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Custom Based Ddial Software / Retro-Dial v1.0b-Linux.</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">PC-Compaq-ipaq Mini-tower Solid State Flash 128mb</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.digitaldial.us" target="_blank" class="blueLink">http://www.digitaldial.us</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://digitaldial.us/fterm/digitaldial.html" target="_blank" class="blueLink">http://digitaldial.us/fterm/digitaldial.html</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Miami, Florida</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 27, 2022, 11:47 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Old SchOOl DiversiDial Chat - RetroDial - 24/7!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=29" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">eaglewing bbs</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Eaglewing</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">tlocbbs.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/EagleWing.jpg" target="_blank"><img width="165" src="images/EagleWing.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">color64 7.37</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">c64c with firedrive 2k 1 sd2uiec,thunderdrive,rs232 userport adapter</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">St. Louis, Missouri</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 23, 2023, 3:50 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=36" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">enlight</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">cygnus</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">enlight.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">SPBBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Linux</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 25, 2023, 4:30 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">SPBBS development system</td>
<td class="bbse"><a href="editbbs.php?bbs_id=192" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Enterprise BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Capt Kirk</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">enterprisebbs.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">1701</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 V7.37</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128,1541,1571,Pi1541</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 1, 2020, 3:11 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=157" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Fria Bad BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Jucke</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">friabad.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/2023-9-30-14-50-21-friabadmaneter.png" target="_blank"><img width="165" src="images/2023-9-30-14-50-21-friabadmaneter.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">c*base 3.3.9 by Tao</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">c64, 8gb CMD HD, JiffyDos</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Fria Bad beach, Helsingborg, Sweden</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 16, 2022, 12:22 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">HQ of Judas & Dinasours, specializing in petscii, fake scene & rare files</td>
<td class="bbse"><a href="editbbs.php?bbs_id=185" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">FRoZEN FLoPPY BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">m00p</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">telnet://bbs.retrohack.se</td>
<td rowspan="8" class="bbsi"><a href="images/frozenfloppy.jpg" target="_blank"><img width="165" src="images/frozenfloppy.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C*BASE v.3.3.8</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 64, ThunderDrive 4GB, SwiftLink, JiffyDOS</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Sweden</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 27, 2021, 10:16 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">ELiTE SCENE BBS! </td>
<td class="bbse"><a href="editbbs.php?bbs_id=94" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Geneticx-PET</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Codetsu</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">g-point.tunk.org</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">1025</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 3.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64 LINK232 Wifimodem 2x SD2iec</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Finland</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 26, 2020, 1:33 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">No More BETA new start 23.12.2020</td>
<td class="bbse"><a href="editbbs.php?bbs_id=161" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Grupo Commodore Argentina</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Juan</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">lu8fjh-c64.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/grupo.jpg" target="_blank"><img width="165" src="images/grupo.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Petscii - BBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Linux - PC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://www.facebook.com/groups/Commodore64Arg</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Argentina</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 7, 2020, 10:27 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Info, Retro game. chats . Internet</td>
<td class="bbse"><a href="editbbs.php?bbs_id=158" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Heights BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Falken</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">heightsbbs.heightspc.net</td>
<td rowspan="8" class="bbsi"><a href="images/2019-2-23-17-18-13-cnet_login.jpg" target="_blank"><img width="165" src="images/2019-2-23-17-18-13-cnet_login.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6860</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">CNET 5.21b</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">A4000D</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://www.facebook.com/heightsbbs</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://embed.ftelnet.ca/?Hostname=heightsbbs.heightspc.net&Port=6860&Proxy=proxy-us-ga.ftelnet.ca&Pr" target="_blank" class="blueLink">http://embed.ftelnet.ca/?Hostname=heightsbbs.heightspc.net&Port=6860&Proxy=proxy-us-ga.ftelnet.ca&Pr</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Tucson, AZ</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 6, 2019, 3:04 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=125" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">High Desert</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Geo455</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">highdesertbbs.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color64 v7.37</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128, SD2IEC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lancaster,CA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 23, 2019, 4:07 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=143" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Image 2.0 HQ</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">X-Tec</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cib.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6407</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 2.0 R3.1</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128/64 Mode, Hyperdrive, Thunderdrive, FD-4K, GLINK-LT</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lakeland, FL</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 3, 2019, 5:21 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Image 2.0 development and main support site.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=107" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Insane Retro Chip</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Blast00n</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">ircbbs.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">5023</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Synchronet</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Raspberry Pi 1 Model B</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 31, 2021, 12:12 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">BBS dedicated only to italian Commodore demoscene with a large file section. Running on RasPi 1B and supports both 40 and 80 column terminals. Telnet and Dial-Up available.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=171" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Java Zone</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">dr coomer</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">2.tcp.ngrok.io</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">11892</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Java</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Windows server</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">n/a</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 12, 2021, 1:30 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Run help for a list of commands! ALSO Connect with this > https://youfiles.herokuapp.com/telnetclient/</td>
<td class="bbse"><a href="editbbs.php?bbs_id=162" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Lost Caverns (Node 1)</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">CommodoreMo</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">tlcbbs.dynu.net</td>
<td rowspan="8" class="bbsi"><a href="images/lostcaverns1.jpg" target="_blank"><img width="165" src="images/lostcaverns1.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Centipede</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128, RA Hyperdrive(LtK clone), RA Ultramux, internal Swiftlink/Wifi @38.4k</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Macomb Township, MI</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">March 26, 2023, 5:42 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Dual line BBS running on real C128's.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=10" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Lost Caverns (Node 2)</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">CommodoreMo</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">tlcbbs.dynu.net</td>
<td rowspan="8" class="bbsi"><a href="images/lostcaverns1.jpg" target="_blank"><img width="165" src="images/lostcaverns1.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6401</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Centipede</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128, RA Hyperdrive(LtK clone), RA Ultramux, internal Swiftlink/Wifi @38.4k</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Macomb Township, MI</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">March 26, 2023, 5:43 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Dual line BBS running on real C128's.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=11" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">LU8FJH BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">JUAN</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">lu8fjh-c64.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6401</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 2.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Vice </td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Argentina </td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 27, 2021, 2:45 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=164" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">LU8FJH IMAGE BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Juan</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">lu8fjh-image.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">IMAGE</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Vice</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://lu8fjh.ampr.org" target="_blank" class="blueLink">http://lu8fjh.ampr.org</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Argentina</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 29, 2022, 9:46 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=184" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">LU8FJH RETRO BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">JUAN</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">lu8fjh-c64.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6402</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Retro64 BBS - TURBO56K</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Linux</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Argentina</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">May 1, 2022, 12:22 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">TURBO56K BBS only acces with RETROTERM - Multimedia Bbs - Music, Radios online ,IRC ,wiki</td>
<td class="bbse"><a href="editbbs.php?bbs_id=177" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">LV-426</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">The Alien</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">lv426bbs.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/lv426.jpg" target="_blank"><img width="165" src="images/lv426.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6464</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Cnet Amiga Pro v5.21b</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Amiga</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">?</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Va Beach, VA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 15, 2023, 6:10 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=4" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Mad World</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">CyberJank</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">www.madworldbbs.com</td>
<td rowspan="8" class="bbsi"><a href="images/madworld.png" target="_blank"><img width="165" src="images/madworld.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">52146</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Centipede</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128 Flat, CMD HD 4gig, Turbo 232</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None Yet</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Kansas City, MO</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 26, 2023, 10:56 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Testing a new way to connect, let's see how well this works....</td>
<td class="bbse"><a href="editbbs.php?bbs_id=12" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Mamba BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Easy_Rider</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">mambabbs.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">2020</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Mystic</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">PC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Warsaw, Poland</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 11, 2020, 6:42 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Amiga/C64 warez, old scene board, MYSTiC Polish HQ</td>
<td class="bbse"><a href="editbbs.php?bbs_id=156" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Microtown BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Jeff Vacha</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">microtownbbs.com</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Online 64 Cgbbs</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 128 (64 mode), Lt Kernal, Retrorewind WIFI Modem</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Princeton, NJ</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 12, 2023, 11:42 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Original Online 64 Cgbbs Software. Back after 30 years</td>
<td class="bbse"><a href="editbbs.php?bbs_id=190" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Motherboard BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Mother</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">mb.oldschoolbbs.com</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6502</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">DS-II 128</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128 - Lt. Kernal - CMD HD - U2+</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.oldschoolbbs.com" target="_blank" class="blueLink">http://www.oldschoolbbs.com</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Panama City, FL</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 27, 2023, 7:00 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Pre-release test bed</td>
<td class="bbse"><a href="editbbs.php?bbs_id=126" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">MS & RD BBs</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Michael Nozy Falzon</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.mozysswamp.org</td>
<td rowspan="8" class="bbsi"><a href="images/ms-rd.png" target="_blank"><img width="165" src="images/ms-rd.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Synchronet</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Mix Systems</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://bbs.mozysswamp.org</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">bbsweb.mozysswamp.org</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Melbourne Victoria Australia</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">June 14, 2020, 9:43 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">BBS for all the way back in 1993 we do have fidonet too</td>
<td class="bbse"><a href="editbbs.php?bbs_id=155" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Online BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Pentangle</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">http://online-bbs.selfhost.bz/</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Prometheus</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">PC via WinUAE</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://online-bbs.selfhost.bz/" target="_blank" class="blueLink">http://online-bbs.selfhost.bz/</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Germany</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 22, 2022, 7:42 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Amiga & C64 (Aminet Mirror)</td>
<td class="bbse"><a href="editbbs.php?bbs_id=183" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Optical Illusion</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Optic Freeze</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">optical.c64bbs.nu</td>
<td rowspan="8" class="bbsi"><a href="images/2019-2-23-17-21-40-img_0465.jpeg" target="_blank"><img width="165" src="images/2019-2-23-17-21-40-img_0465.jpeg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C*Base 3.1 Holy Moses Mod</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64 Reloaded MK1, SuperCPU, RamLink, Rear Admiral ThunderDrive, FireDrive 2K, Sd2iec, GGLabs GG232T</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 27, 2019, 11:07 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Genesis*Project - Atlantis - Hokuto Force USHQ</td>
<td class="bbse"><a href="editbbs.php?bbs_id=131" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Particles! BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Ice Breaker</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">particlesbbs.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Centipede 128</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 128DCR, JiffyDOS, 1MB RAM Expansion, Swiftlink, 4GB CMD</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.particles.org, http://www.facebook.com/particlesbbs" target="_blank" class="blueLink">http://www.particles.org, http://www.facebook.com/particlesbbs</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://www.particles.org" target="_blank" class="blueLink">http://www.particles.org</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Bentonville, Arkansas, U.S.A.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 8, 2016, 4:22 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Over 120 File Areas, GEOS, Plus/4, CP/M, C64, 128. Usenet feed, and Retro Usenet Feed. 40/80 Columns, ASCII/PETSCII/ANSI. 70+ Online Games.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=22" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">PETSCII Playground</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Pete Rittwage</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">c64preservation.com</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6464</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Homemade Linux Daemon</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Centos Linux </td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">c64preservation.com</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Augusta, GA USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">June 3, 2017, 2:51 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Test Framework for multi-user BBS in C on Linux</td>
<td class="bbse"><a href="editbbs.php?bbs_id=100" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Pinball Underground</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Leachdude</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">pcpl.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 V8</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">WinvVice</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Jackson, MI</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 11, 2017, 5:45 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Home of the Prison City Pinball League</td>
<td class="bbse"><a href="editbbs.php?bbs_id=95" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">RapidFire</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">pcollins</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">rapidfire.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/rapidfire.png" target="_blank"><img width="165" src="images/rapidfire.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Cyborg CBase (Holy Moses Mod) 38.4K!</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64, U64 Elite (48Mhz), 2 x Thunderdrives</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Germany</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">March 18, 2021, 9:17 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Excess, Laxity & Fairlight HQ </td>
<td class="bbse"><a href="editbbs.php?bbs_id=99" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Raveolution</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Larry</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">raveolution.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/2018-9-21-22-45-6-ravescreen.png" target="_blank"><img width="165" src="images/2018-9-21-22-45-6-ravescreen.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">HolyMoses modded C*Base 3.1 / 38.4K Baud</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64R MK2, Swiftlink, SCPU, RamLink, HD</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Germany</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 21, 2018, 7:28 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">ROLE WHQ</td>
<td class="bbse"><a href="editbbs.php?bbs_id=116" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Reflections BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Stablizer</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">reflections.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/2017-reflectionBBS.png" target="_blank"><img width="165" src="images/2017-reflectionBBS.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">CBase 3.1 (Moses Modded) + Custom Mods</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 128D, SuperCPU 128 (20mhz), 8.2 GB ThunderDrive, RAMLink, FD4000, FD2000 and lots more! Supporting speeds up to 57,600 bps!</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Denver, CO. USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 10, 2020, 10:45 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">ExCeSs - Demonix - Laxity - Longshot - Onslaught HQ!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=84" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Reign of Fire</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Spitfire</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">call.rofbbs.com</td>
<td rowspan="8" class="bbsi"><a href="images/rof.png" target="_blank"><img width="165" src="images/rof.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6800</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Net Amiga</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Emulated C= Amiga AGA 040 - Supports ANSI, PETSCII and SKYPIX Graphics. 40 and 80 columns.</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.rofbbs.com" target="_blank" class="blueLink">http://www.rofbbs.com</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://www.rofbbs.com/term.html" target="_blank" class="blueLink">http://www.rofbbs.com/term.html</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Chattanooga Tennessee</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 12, 2023, 3:27 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Dial-Up: (432) 541-8271</td>
<td class="bbse"><a href="editbbs.php?bbs_id=129" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Reign of Fire II</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Spitfire</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">call.rofbbs.com</td>
<td rowspan="8" class="bbsi"><a href="images/rof2.png" target="_blank"><img width="165" src="images/rof2.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Net 64 DS-2</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64, 1541, 1571, uIEC/SD, Turbo232, JiffyDOS, 1702 Monitor.</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.rofbbs.com" target="_blank" class="blueLink">http://www.rofbbs.com</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://www.rofbbs.com/term.html" target="_blank" class="blueLink">http://www.rofbbs.com/term.html</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Chattanooga Tennessee</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 23, 2022, 2:47 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">A rare C-Net 64 DS-2 BBS with 40 column CG support! 300-38.4k Baud!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=149" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Reign of Fire III</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Spitfire</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">call.rofbbs.com</td>
<td rowspan="8" class="bbsi"><a href="images/rof3.png" target="_blank"><img width="165" src="images/rof3.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">8502</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Net 128</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128, 1750 REU, 1541, 1541-II, 1581, uIEC/SD, Turbo232, JiffyDOS, 2002 Monitor.</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.rofbbs.com" target="_blank" class="blueLink">http://www.rofbbs.com</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://www.rofbbs.com/term.html" target="_blank" class="blueLink">http://www.rofbbs.com/term.html</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Chattanooga Tennessee</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 12, 2023, 3:26 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">A rare C-Net 128 BBS. Supports 40/80 Columns ANSI and CG Graphics! 300-38.4k Baud</td>
<td class="bbse"><a href="editbbs.php?bbs_id=154" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Remote CPU BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Deadman</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">remotecpu.com</td>
<td rowspan="8" class="bbsi"><a href="images/2015-6-11-4-8-9-remotecpubbs.jpg" target="_blank"><img width="165" src="images/2015-6-11-4-8-9-remotecpubbs.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6502</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2b</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">64C, CMD HD (4.1GB), Swiftlink, Uiec/SD, Network Flyer, JiffyDOS</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://commodore.software" target="_blank" class="blueLink">http://commodore.software</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Marquette, Michigan</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">June 9, 2017, 3:47 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">24/7 - 365 Days </td>
<td class="bbse"><a href="editbbs.php?bbs_id=54" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Retro BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Outsoft</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">retrobbs.sinclair.homepc.it</td>
<td rowspan="8" class="bbsi"><a href="images/sinclair.jpg" target="_blank"><img width="165" src="images/sinclair.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Mystic BBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Hosted in Ubuntu on my Mac ;)</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">retrobbs.sinclair.homepc.it</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://telnetbbsguide.com/bbs/sinclair-retro-bbs/" target="_blank" class="blueLink">http://telnetbbsguide.com/bbs/sinclair-retro-bbs/</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Mantua (Italy)</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">2/28/2018</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">A Sinclair Retro BBS but works well on C-64 too ;)</td>
<td class="bbse"><a href="editbbs.php?bbs_id=108" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Retroacademy</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Francesco Sblendorio</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.retroacademy.it</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Petscii BBS Builder: https://github.com/sblendorio/petscii-bbs/</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Virtual amd64 server with Debian Linux</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">www.retroacademy.it</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">United Kingdom</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 9, 2019, 9:22 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Language: Italian</td>
<td class="bbse"><a href="editbbs.php?bbs_id=132" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Retrograde</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">X-Tec</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cib.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/retrograde3.png" target="_blank"><img width="165" src="images/retrograde3.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6428</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">IMAGE 3.0 </td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Win10 i7 Vice 3.5, SuperCPU, CMD HD, RAMLink tcpser 38.4Kbps</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lakeland, FL</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 25, 2021, 3:33 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Birthplace of Image 3.0. Fixes, Games, all the latest 3.0 files Full Sysop support</td>
<td class="bbse"><a href="editbbs.php?bbs_id=13" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Riktronics</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">J.Rotten</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">rkbbs.net</td>
<td rowspan="8" class="bbsi"><a href="images/rkbbs.jpg" target="_blank"><img width="165" src="images/rkbbs.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2a</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.rkbbs.net" target="_blank" class="blueLink">http://www.rkbbs.net</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Boones Mill, Virginia, U.S.A.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">June 30, 2013, 6:03 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=14" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Sanctuary</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Sandman</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">sanctuary.zapto.org</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">1541</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">AmiExpress 4.20</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">WinUAE</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://sanctuary.brysk.se/" target="_blank" class="blueLink">http://sanctuary.brysk.se/</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://brysk.se/bbs/html/connect.html" target="_blank" class="blueLink">http://brysk.se/bbs/html/connect.html</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Gothenburg / SWEDEN</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 23, 2019, 1:39 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Amiga BBS</td>
<td class="bbse"><a href="editbbs.php?bbs_id=144" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Satellite 4</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Phisbin</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">Satellite4.dynu.net</td>
<td rowspan="8" class="bbsi"><a href="images/satellite-4.png" target="_blank"><img width="165" src="images/satellite-4.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">color 64</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64 Breadbin,CMD Thunder drive,1581,swiftlink38400baud 1764REU</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Pennsylvania</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">March 18, 2020, 12:44 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Starting up for the first time, check it out and leave feedback please!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=151" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">SD2IEC Test BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">X-TEC</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cib.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/SD2IEC_Test_BBS.jpg" target="_blank"><img width="165" src="images/SD2IEC_Test_BBS.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6403</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2b Networked</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64,SuperCPU,RAMLink,SD2IEC (x2),1541/71/81</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lakeland, Florida</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 22, 2016, 9:31 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Swiftlink 19.2k, Running at 20Mhz Turbo mode. Netted Subs, Games, UDs available online.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=81" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Second Coming BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Crackerjak</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">scbbs.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/2019-2-23-17-15-33-screengrab.jpg" target="_blank"><img width="165" src="images/2019-2-23-17-15-33-screengrab.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">CNet BBS v5.21b</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Dell tower running Win7 Pro, WinUAE 64-bit</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://embed.ftelnet.ca/?Hostname=scbbs.ddns.net&Port=6400&Proxy=proxy-us-ga.ftelnet.ca&ProxyPort=80" target="_blank" class="blueLink">http://embed.ftelnet.ca/?Hostname=scbbs.ddns.net&Port=6400&Proxy=proxy-us-ga.ftelnet.ca&ProxyPort=80</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Kankakee, Il, USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 14, 2018, 3:43 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">50+Pfiles, BBSLink, RetroNet, C=Net, FidoNet, gigs of files</td>
<td class="bbse"><a href="editbbs.php?bbs_id=128" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">SilverHawk BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Stian Andre Olsen & Espen Skog</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.silverhawk.me</td>
<td rowspan="8" class="bbsi"><a href="images/SilverHawkbbs.jpg" target="_blank"><img width="165" src="images/SilverHawkbbs.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">ABBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">FS-UAE on OSX</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.silverhawk.me" target="_blank" class="blueLink">http://www.silverhawk.me</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Norway</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 27, 2017, 3:49 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">See setup instructions on the website. We run ABBS on FS-UAE. Board has been alive since 1992.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=46" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Smashbot.com</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Smashbot</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">Smashbot.com</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Citadel </td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">VPS</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://www.smashbot.com</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Cedar Knolls, New Jersey USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 14, 2023, 8:05 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Web or telnet accessible, C64 and H/P Subs. True citadel modern experience. Text client is preferred on telnet port 23. </td>
<td class="bbse"><a href="editbbs.php?bbs_id=165" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Starbug BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Kryten</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">starbugbbs.com</td>
<td rowspan="8" class="bbsi"><a href="images/2023-09-30-starbugbbs.png" target="_blank"><img width="165" src="images/2023-09-30-starbugbbs.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Synchronet 3.19b</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Windows 11 i9</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Kent, UK</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 25, 2023, 5:44 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Dedicated to the Amiga Computer</td>
<td class="bbse"><a href="editbbs.php?bbs_id=191" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">SUB ZERO BBS!</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">XxSwitchBladexX</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">szbbs.zapto.org</td>
<td rowspan="8" class="bbsi"><a href="images/2016-7-2-3-41-59-subzero.jpg" target="_blank"><img width="165" src="images/2016-7-2-3-41-59-subzero.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">2400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Millennium 128 BBS - UPDATED BIWEEKLY!</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">64 BIT OS WIN 10 - Winvice 3.4 EMU-128 (MODE) 80 (COLUMN) - CMD HD</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.digitaldial.us" target="_blank" class="blueLink">http://www.digitaldial.us</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Miami, FL.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 21, 2021, 12:55 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">New 128 Version 1.0</td>
<td class="bbse"><a href="editbbs.php?bbs_id=61" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Surf Shop BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Board Rider</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">ssbbs.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/surfshop.jpg" target="_blank"><img width="165" src="images/surfshop.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 V8.1</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64C,CMD-HD (4GB),FD-2000,Ultimate 1541-II+</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Williamston, NC</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 28, 2021, 9:45 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Awesome BBS!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=68" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Surf Shop BBS #2</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Board Rider</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">ssbbs.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6502</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">TaoMod+ C*Base 64</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">128D, uIEC, Link232-WiFi</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Williamston, NC</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 23, 2023, 4:39 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=86" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">System One BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Captain Sulu, Co-Sysop: X-Tec</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cib.dyndns.org</td>
<td rowspan="8" class="bbsi"><a href="images/2018-9-21-22-42-57-syssnip.png" target="_blank"><img width="165" src="images/2018-9-21-22-42-57-syssnip.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6491</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 3.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Vice 3.5, SCPU 20 Mhz, CMD HD</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lakeland, FL</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">June 26, 2022, 4:48 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Western US NISSA HQ</td>
<td class="bbse"><a href="editbbs.php?bbs_id=92" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Temporal Vortex BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Jeff Ledger</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.c64.xyz</td>
<td rowspan="8" class="bbsi"><a href="images/temporal.jpg" target="_blank"><img width="165" src="images/temporal.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">TVBBS (Custom petscii-bbs software)</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Linux System</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Orrville, OH</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 24, 2020, 3:22 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=153" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Amiga Frontier BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">KrUpTiOn</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">frontierbbs.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">8888</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Enigma</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://frontierbbs.net" target="_blank" class="blueLink">http://frontierbbs.net</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Akron, Ohio</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 30, 2019, 1:09 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Online Games/Doors, Over 12k Amiga Files, Amiga Echomail Areas</td>
<td class="bbse"><a href="editbbs.php?bbs_id=145" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Dead Zone</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Trouble/Onslaught</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">dzbbs.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/2018-9-21-22-40-8-petscii_thedeadzone.png" target="_blank"><img width="165" src="images/2018-9-21-22-40-8-petscii_thedeadzone.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Cyborg/Moses Modded C*Base</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 64 BreadBin, WiModem, CMD HD (1 Gig) JiffyDos</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Philadelphia, PA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 21, 2018, 5:09 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">World Hq for ONSLAUGHT!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=122" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Fone Company (Color 64 flavor)</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Rick</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">tfcbbs.com</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6464</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64/Network 64</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C=64 (bread bin), uIEC/SD 8GB, VIC-1011A</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://tfcbbs.com" target="_blank" class="blueLink">http://tfcbbs.com</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"><a href="http://tfcbbs.com" target="_blank" class="blueLink">http://tfcbbs.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Winston-Salem, NC</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 19, 2019, 3:56 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Sister site to our Supra 128 BBS; Color 64 mods & support</td>
<td class="bbse"><a href="editbbs.php?bbs_id=139" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Fone Company (Supra 128 flavor)</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Rick</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">tfcbbs.com</td>
<td rowspan="8" class="bbsi"><a href="images/2019-2-23-17-27-12-screen-fone-company.png" target="_blank"><img width="165" src="images/2019-2-23-17-27-12-screen-fone-company.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Supra 128 Network v4.6.1n</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 128, Lt. Kernal, 1581, GGLink RS-232</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://tfcbbs.com/" target="_blank" class="blueLink">http://tfcbbs.com/</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">https://color64.com/terminal/</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Winston-Salem, NC</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 19, 2019, 3:55 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">The first and (so far only) Supra 128 BBS on telnet! Now supporting and maintaining Supra 128 and Color 64 BBS. 24/7/365. Use of a Commodore terminal or terminal emulator (such as CGTerm) is strongly recommended! If you are interested in running a Supra 128 BBS please ask!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=136" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Hidden</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">LA-STYLE</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">the-hidden.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/thehidden.png" target="_blank"><img width="165" src="images/thehidden.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">CyborgMod C-Base @ 9600 BPS!</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64, 1GB CMD</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 16, 2017, 1:27 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">10 Subs & UD Areas!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=52" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Oasis BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Desert-Fox & Havok</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">oasisbbs.hopto.org</td>
<td rowspan="8" class="bbsi"><a href="images/oasis.png" target="_blank"><img width="165" src="images/oasis.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 BBS v7.37</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 64 w/ Rear Admiral ThunderDrive (4.1 GB)</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.theoasisbbs.com" target="_blank" class="blueLink">http://www.theoasisbbs.com</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Chesapeake, VA. USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">June 5, 2017, 11:44 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Color 64 BBS v7 Preservation and Support Site</td>
<td class="bbse"><a href="editbbs.php?bbs_id=101" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Old Net</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Richard Bettridge</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">theoldnet.com</td>
<td rowspan="8" class="bbsi"><a href="images/2019-11-6-17-29-17-image.png" target="_blank"><img width="165" src="images/2019-11-6-17-29-17-image.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Custom Internet Browser</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Linux Machine</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://theoldnet.com" target="_blank" class="blueLink">http://theoldnet.com</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Waterloo, Ontario, Canada</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 5, 2019, 5:15 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Browse the Internet Archive from your C64!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=146" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Valley</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">The Keymaster (SysOp), Scratcher (CoSysop)</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">valley64.com</td>
<td rowspan="8" class="bbsi"><a href="images/thevalley.png" target="_blank"><img width="165" src="images/thevalley.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Base 3.0 TKM Mod</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128 in 64 mode. sd2iec, zoomfloppy, CMD 4.3 GB SSD, Turbo-232, Turbomaster 4.09 Accelerator, MASTER ADAPTER, Raspberry Pi, TCPSER</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://connect2400.com</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Cedar Knolls, NJ USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 27, 2023, 7:16 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Genesis*Project US HQ</td>
<td class="bbse"><a href="editbbs.php?bbs_id=59" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The WAC BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">nglayton</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">wacbbs.ddns.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6502</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Warp6</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Apple //gs, BlueSCSI, 100+ Megs, door games,</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Oregon</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 25, 2022, 7:43 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">The original Willamette Apple Connection BBS back online after 30years</td>
<td class="bbse"><a href="editbbs.php?bbs_id=182" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Wrong Number V</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Bucko</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">wn2.duckdns.org</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6408</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image BBS V2.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Emulated WinVice 3.2 i3 3.3Ghz 500GIG HD</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Yorktown Heights, NY</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 12, 2018, 3:41 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Image BBS v2.0 Programmers System. Testing the latest updates to the Image BBS v2.0</td>
<td class="bbse"><a href="editbbs.php?bbs_id=127" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Wrong Number ]I[ BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Al DeRosa</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">wn2.duckdns.org</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">CNet AmigaPro v5.21b</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">WinUAE PC i3 3.3ghz</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Yorktown Heights NY</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 12, 2018, 2:42 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=124" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Zelch BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">The Zacman</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">coffeemud.net</td>
<td rowspan="8" class="bbsi"><a href="images/zelch128.jpg" target="_blank"><img width="165" src="images/zelch128.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6502</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Zelch 128 v2.5a</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 128, C64Net WiFi, SD2IEC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://zimmers.net/commie/telb.html" target="_blank" class="blueLink">http://zimmers.net/commie/telb.html</a></td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Round Rock, TX</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 8, 2021, 12:05 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">The original C= Telnet BBS is back!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=168" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">TheMajorBBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Phil Taylor</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">majorbbs.ddnsfree.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">4000</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Major BBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Windows</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://sbbs.dynu.net/majorbbs/</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">Yes</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Virginia</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 26, 2022, 6:51 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Support ing Commodore 64/128 with 254 available nodes The Best bbs around</td>
<td class="bbse"><a href="editbbs.php?bbs_id=175" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Thierrys Lair</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Thierry</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">thierryslair.dynet.com</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">RetroBBS TURBO56K</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Linux PC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Cordoba, Argentina</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 21, 2021, 12:18 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Multimedia BBS, requires Retroterm to connect</td>
<td class="bbse"><a href="editbbs.php?bbs_id=170" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">UKBBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Mantrid</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">ukbbs.zapto.org</td>
<td rowspan="8" class="bbsi"><a href="images/ukbbs.png" target="_blank"><img width="165" src="images/ukbbs.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">synchronet</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">raspberry pi </td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Co. Durham, UK</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 3, 2020, 10:24 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">for 40 col C64 mode use port 64, for 80 col mode use port 128</td>
<td class="bbse"><a href="editbbs.php?bbs_id=159" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">UZi SUiCiDE BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">don27dog</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">Uzisuicide.servebbs.org </td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Ami Express v5.2</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Amiga 3000T</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 24, 2020, 2:35 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">C64,Amiga,Ascii/Ansi</td>
<td class="bbse"><a href="editbbs.php?bbs_id=152" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Veleno BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">F. Krueger</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">telnet.velenobbs.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">SynchroNet 3.20</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">www.velenobbs.net</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Verona</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">May 5, 2023, 4:42 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=189" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Willow Creek BBS</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Pawprintlogic</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">willowcreekbbs.dynu.net</td>
<td rowspan="8" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64c, Thunderdrive</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">www.willowcreekbbsonline.com</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Carol Stream, IL</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 12, 2019, 2:56 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Western Themed</td>
<td class="bbse"><a href="editbbs.php?bbs_id=137" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">WORDLE64</td>
<td rowspan="2" class="bbss" bgcolor='#66cc66'>Status: Online</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Mango</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">wordle64.mywire.org</td>
<td rowspan="8" class="bbsi"><a href="images/c64-wordle.png" target="_blank"><img width="165" src="images/c64-wordle.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">8864</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">python https://github.com/jalbarracinv/python-cbm-petscii-bbs</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Xeon</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Flash Terminal:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lima, Peru</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 10, 2022, 5:35 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Come play</td>
<td class="bbse"><a href="editbbs.php?bbs_id=173" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<button style="font-size:14px" onclick="goToURL()">Add a BBS to the list</button>
<br><br>
<table class='bbs'><tr><td class='bbss' bgcolor='#ff3300'><b>77 Boards Offline:</b></td></tr></table><br> <table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd"> Scorp's Portal</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Scorpion</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">scorp.us.to</td>
<td rowspan="7" class="bbsi"><a href="images/64blazer_000.png" target="_blank"><img width="165" src="images/64blazer_000.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 v8.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">WinVICE/TCPSER, JiffyDOS</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://scorpsportal.com" target="_blank" class="blueLink">http://scorpsportal.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Shanghai, China</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 1, 2018, 4:54 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">China's onliest Commodore 64 BBS</td>
<td class="bbse"><a href="editbbs.php?bbs_id=62" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">13th Floor BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Hoy Brothers</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">13th.hoyvision.com</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.3 Telnet</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128 - SD2IEC - Swiftlink</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">www.hoyvision.com</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Oak Ridge, TN</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 23, 2018, 11:13 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Restored from April 1993 content</td>
<td class="bbse"><a href="editbbs.php?bbs_id=118" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">64 Hot Line BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Tommy</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.dynu.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Protovision Turbo 64</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Emulated C64 w/ 2 d64 disk images</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">May 4, 2014, 8:27 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=63" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Afterlife</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Alwyz</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">afterlife.dynu.com</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color64 v8 Alwyz Edition</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64 - Swiftlink - uIEC - 1581</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://1200baud.wordpress.com" target="_blank" class="blueLink">http://1200baud.wordpress.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">NYC</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 28, 2020, 6:50 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Latest NTSC Warez. Thousands of Textfiles, Cool peeps, Good times</td>
<td class="bbse"><a href="editbbs.php?bbs_id=93" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Altered Dimensions</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Blackflag</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">altd.dyndns.org</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2b</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C=64C, CMD SuperCPU , CMD HD-40, Swiftlink Cartridge 19.2k baud</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Long Island, NY</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 1, 2018, 3:09 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=111" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Altiworld BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">King Durin</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.altiworld.com</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">WorldBankBBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">GoDaddy VM</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.altiworld.com" target="_blank" class="blueLink">http://www.altiworld.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Clarksville, TN</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 16, 2018, 11:36 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Runs on WorldBankBBS Software</td>
<td class="bbse"><a href="editbbs.php?bbs_id=58" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Altiworld BBS ANSI</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">King Durin</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.altiworld.com</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">513</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">WorldBankBBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">GoDaddy VM</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.altiworld.com" target="_blank" class="blueLink">http://www.altiworld.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Clarksville, TN</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 16, 2018, 11:37 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Runs on WorldBankBBS Software</td>
<td class="bbse"><a href="editbbs.php?bbs_id=91" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Amiga City</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">MarisaG</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">AmigaCity.xyz</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Synchronet</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Linux on Ubuntu</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">https://AmigaCity.xyz</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">South San Francisco, CA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 16, 2018, 7:50 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">ssh available at port 3459</td>
<td class="bbse"><a href="editbbs.php?bbs_id=102" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Amiga-Z BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Rich Lawrence</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">amigazbbs.noip.me</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Net Amiga</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Amiga</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 1, 2015, 2:39 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">New C-Net Amiga BBS... Login Today!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=76" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Backwater Dreams</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Floyd</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">backwater.servebbs.com</td>
<td rowspan="7" class="bbsi"><a href="images/backwaterIvory.jpg" target="_blank"><img width="165" src="images/backwaterIvory.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2a</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128D in 64 mode, 158, 1571, JiffyDOS, CMD HD 600 MB!</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://backwater.servebbs.com" target="_blank" class="blueLink">http://backwater.servebbs.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">St Louis, Missouri USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 11, 2010, 12:31 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">CMD HD craped out again... will get it back online soon.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=1" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">bff-BBS 1 / bff-BBS 2</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Intergalactic-whinner</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">None</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">Dial-up!</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 64</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.bff-fbi.com" target="_blank" class="blueLink">http://www.bff-fbi.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Winnersville </td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">June 6, 2012, 7:21 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Working to put it on my sweet 286.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=38" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">BlackOrb</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Lord Magnum</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">blackorb-bbs.ddns.net </td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Winvice</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">winvice 64 running Jiffydos on PC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Beaumont Texas</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 1, 2019, 5:48 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">New domain address</td>
<td class="bbse"><a href="editbbs.php?bbs_id=142" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">BlackOrb</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Lord Magnum</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">blackorb.mynetgear.com</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Net 64 DS2</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Winvice 64</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Beaumont Texas</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 1, 2019, 5:49 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=141" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">blinkenlights</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">blinkenlights</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">towel.blinkenlights.nl</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">25</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 4, 2015, 3:45 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">This is not a BBS, Nor Commodore related in the BBS users opinions discussed so i will put it on the offline side till deleted. - Chris537/csd</td>
<td class="bbse"><a href="editbbs.php?bbs_id=71" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">C-Net 128 v6.6</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Overlord</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">fodim.bounceme.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Net 128 v6.6 (Rare)</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">c128/Lt.K/1084S/1571541</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Manchester, PA, USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 18, 2011, 10:10 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">If anyone has a users manual for this package let me know!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=51" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">CarrierSync II BBS!</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">XxSwitchBladexX</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">carriersync2.thruhere.net</td>
<td rowspan="7" class="bbsi"><a href="images/CarrierSyncII.jpg" target="_blank"><img width="165" src="images/CarrierSyncII.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6912</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Synchronet BBS Software V3.14</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Pentium4 Winxp PRO - 20GHD.</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.digitaldial.us" target="_blank" class="blueLink">http://www.digitaldial.us</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Miami, FL - Three Zero Five!</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 17, 2017, 3:21 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Dovenet, SUBS, ANSI BBS.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=60" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Castle HQ BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">David Snyder</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">castlehqbbs.us</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2a</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">WinVice/TCPSER</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">March 6, 2015, 4:34 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">New Image BBS</td>
<td class="bbse"><a href="editbbs.php?bbs_id=70" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Cats Claw BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Silentcat</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">catsclawbbs.sytes.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Utah</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">March 3, 2013, 12:09 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Press enter a couple times after connected. </td>
<td class="bbse"><a href="editbbs.php?bbs_id=57" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Centronian BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Alterus</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.centronian.ca</td>
<td rowspan="7" class="bbsi"><a href="images/2019-2-23-17-9-11-centronian-magnetar.png" target="_blank"><img width="165" src="images/2019-2-23-17-9-11-centronian-magnetar.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Magnetar BBS - High speed RR-NET software based on contiki</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64 + Turbo Chameleon + RR-NET + SD2IEC + JiffyDOS</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://bbs.centronian.ca" target="_blank" class="blueLink">http://bbs.centronian.ca</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Victoria, BC, Canada</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 27, 2021, 9:56 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"> TEMPORARY OFFLINE DUE TO NETWORK ISSUE. - Vic 64 HQ with 80, 40 and 22 column PETSCII support, as well as modern Linux terminals</td>
<td class="bbse"><a href="editbbs.php?bbs_id=80" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Chit-Chat</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">f0ner00t</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">chitchat.mooo.com</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">MultiChat / DDIAL / Diversdial / STS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://arbelos.cluenet.org" target="_blank" class="blueLink">http://arbelos.cluenet.org</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Modesto, CA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 10, 2009, 10:29 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">31 port chat system</td>
<td class="bbse"><a href="editbbs.php?bbs_id=32" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Commodore Mania!</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Don Snider</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cmbbs.org</td>
<td rowspan="7" class="bbsi"><a href="images/commodoremania.png" target="_blank"><img width="165" src="images/commodoremania.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">CMBBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">VICE emulator</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Maryland</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 15, 2016, 11:44 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=88" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Commodore Reloaded</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Andrew Sutton</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">commodorereloaded.servebbs.com</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Ivory BBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">?</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Redford, Mi</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 14, 2008, 8:47 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Work in Progress!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=30" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Commodore World</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Scott Hutter</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">commodoreworld.servebbs.net</td>
<td rowspan="7" class="bbsi"><a href="images/commodoreworld.jpg" target="_blank"><img width="165" src="images/commodoreworld.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Synchronet</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">PC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Spring Hill, TN</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">May 24, 2014, 9:32 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=31" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Commodore4ever BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">c4ever</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">commodore4everbbs.dynu.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color128 (Modded Centipede)</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">128D,CMD HD, CMD Turbo232 with BBS Server</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">commodore4ever.net</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Saluda,SC</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 28, 2020, 6:52 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Only Color128 38400 baud!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=104" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Cottonwood II</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Balzabaar</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">cottonwood.servebbs.com</td>
<td rowspan="7" class="bbsi"><a href="images/cottonwoodintro.jpg" target="_blank"><img width="165" src="images/cottonwoodintro.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 v7.36</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 128 (in 64 mode)</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://cottonwoodbbs.dyndns.org" target="_blank" class="blueLink">http://cottonwoodbbs.dyndns.org</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Moreno Valley, California, U.S.A.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 16, 2011, 5:32 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Message bases, file transfers, online games, and much more!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=48" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Crazy Terminal</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Cosmo Commander</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">crazytermbbs.dyndns.org</td>
<td rowspan="7" class="bbsi"><a href="images/crazyterminal.jpg" target="_blank"><img width="165" src="images/crazyterminal.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2a</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">PC Running WinVICE C64 Emulator</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://crazytermbbs.dyndns.org/" target="_blank" class="blueLink">http://crazytermbbs.dyndns.org/</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Baytown, TX</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 22, 2014, 7:09 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=67" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">DAWN STAR INFORMATION EXCHANGE</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Karyn Roberts</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.dsix.io</td>
<td rowspan="7" class="bbsi"><a href="images/DawnStarAmigaBBS.jpg" target="_blank"><img width="165" src="images/DawnStarAmigaBBS.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">2300</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Net Amiga</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Amiga</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 24, 2016, 2:08 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">New C-Net Amiga BBS... Login Today! Note Port# update.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=75" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Domotron</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Silva D</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.domotron.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Synchronet</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">4 USR V.Everything Modems</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://bbs.domotron.net" target="_blank" class="blueLink">http://bbs.domotron.net</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Las Vegas, Nevada</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 3, 2015, 9:46 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Dialup: [404]800-2008</td>
<td class="bbse"><a href="editbbs.php?bbs_id=74" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Dragon's Eye</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Ryan Sherwood (Pinacolada)</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">dragonseyebbs.dyndns.org</td>
<td rowspan="7" class="bbsi"><a href="images/dragonseye.gif" target="_blank"><img width="165" src="images/dragonseye.gif"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image 1.2a</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64C, JiffyDOS, CMD HD (500 MB)</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">none</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Tacoma, Washington USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 14, 2011, 5:26 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Awesome mods!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=2" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Dream Factory</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Chameleon/CSD</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">dfbbs.zapto.org</td>
<td rowspan="7" class="bbsi"><a href="images/dreamfactory.jpg" target="_blank"><img width="165" src="images/dreamfactory.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64128</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">TaoMod C*Base!</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 64</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">none</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Asheboro, NC</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 13, 2018, 1:13 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Ready For Testing! Please Apply For An Account!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=3" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Elite BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Hershey</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">elitebbs.dynu.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Dragonfire 128 BBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128,Monitor, Thunder Hard Drive, Ramlink</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://elitebbs.dynu.net" target="_blank" class="blueLink">http://elitebbs.dynu.net</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Manitoba, Canada</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 24, 2023, 3:15 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Ring of Chaos onling Game</td>
<td class="bbse"><a href="editbbs.php?bbs_id=50" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Endless Chaos BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Chris537 & Jaz</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">endlesschaos.dyndns.org</td>
<td rowspan="7" class="bbsi"><a href="images/ecbbslogo1.jpg" target="_blank"><img width="165" src="images/ecbbslogo1.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C*Base METALsoft V5.1, Prompts by Chris537</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Online Since 3-12-10, 2400bps RS232, Stock 64C, 1 - HyperDrive (LT.K Clone), 1-uIEC3.1 (Online Games)</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Cincinnati, Ohio</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">October 3, 2020, 4:18 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Alternative Telnet: ecbbs.zapto.org:23. 10 Subs, Online Games.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=45" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Excalibur's Stone</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Eric Hodge (Excalibur)</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.excalibursstone.com</td>
<td rowspan="7" class="bbsi"><a href="images/excaliber.jpg" target="_blank"><img width="165" src="images/excaliber.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">DMBBS v5.3a</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128D in 64 mode, CMD 4GB, RAMLINK 16MB, TCPSER</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://excalibursstone.com" target="_blank" class="blueLink">http://excalibursstone.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Dallas Texas</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 14, 2011, 5:23 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">BBS is fixed and back online as of 01/31/09</td>
<td class="bbse"><a href="editbbs.php?bbs_id=7" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Fourth Dimension</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Overlord/CCI</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">75.186.39.144 or fodim.bounceme.net</td>
<td rowspan="7" class="bbsi"><a href="images/fodim.JPG" target="_blank"><img width="165" src="images/fodim.JPG"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Pre-Alpha Millennium 64 BBS (Hand Written)</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">TCPSER, c64, 4.1GB HD, Jiffy DOS, link232</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Manchester, PA, USA/Hosted Cincy Oh</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 9, 2014, 4:21 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">ONLINE For testing! Give it a ring. Still working on this project. A 100% ML re-write, and time for alpha calls.. Running on real C= hardware and a thunder drive</td>
<td class="bbse"><a href="editbbs.php?bbs_id=33" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Fourth Dimension</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Overlord</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">fodi.bounceme.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Millennium 64 BBS, Written by SysOp!! Daily Development.</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">c64/ThunderDrive/1541/GGLabs Swiftlink Clone,, </td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">York Pa, USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 30, 2023, 4:57 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Shameless plug for my homeade Commodore BBS</td>
<td class="bbse"><a href="editbbs.php?bbs_id=138" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Generation III POT-D</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">black sheep</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">geniv.dyndns.org</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">PCBoard</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">VM on ESXi</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://geniv.com/telnetnew.html" target="_blank" class="blueLink">http://geniv.com/telnetnew.html</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Brooklyn NY</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 28, 2016, 9:43 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">old school </td>
<td class="bbse"><a href="editbbs.php?bbs_id=79" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">HOTWIRE BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">XxSwitchBladexX</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">hotwirebbs.zapto.org</td>
<td rowspan="7" class="bbsi"><a href="images/hotwirebbs.jpg" target="_blank"><img width="165" src="images/hotwirebbs.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6502</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Ivory v3.5</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Winvice 2.4, BBS Server 1.4a, TCP232 converter WinXP</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.digitaldial.us" target="_blank" class="blueLink">http://www.digitaldial.us</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Miami, FL.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">May 31, 2021, 5:07 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Fill out an application at main prompt for new users.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=65" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">HoyVision Hotline (1987)</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Hoy Brothers</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.hoyvision.com</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6420</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Ivory 2.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">WinVICE 1.19 JiffyIEC</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.hoyvision.com" target="_blank" class="blueLink">http://www.hoyvision.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Rocky Top, TN</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 23, 2019, 5:51 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Before being called 13th Floor</td>
<td class="bbse"><a href="editbbs.php?bbs_id=123" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Hurricane BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">c4ever</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">hurricanebbs.dynu.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6401</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Centipede</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">128D, RAMLink, Turbo232, CMD-HD 40, ThunderDrive, FD2000</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Saluda, SC</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 20, 2020, 1:34 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Went LIVE today 9/10/2017. Come check it out!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=106" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Inner Circle</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Eddie</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">innercirclebbs.com</td>
<td rowspan="7" class="bbsi"><a href="images/innercircle.jpg" target="_blank"><img width="165" src="images/innercircle.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Centipede</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128, CHD 4GB, RL, SC128</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">San Diego</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 14, 2011, 5:24 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">C-Net 128 BBS Under Development! RELEASE 6!!!!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=8" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Inner Circle II</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Eddie</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.innercirclebbs.com</td>
<td rowspan="7" class="bbsi"><a href="images/innercircle2.jpg" target="_blank"><img width="165" src="images/innercircle2.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">64000</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Net128 vT1</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128, CHD 4GB, RL, SC128</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">San Diego</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 14, 2011, 5:25 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">C-Net 128 BBS Under Development! RELEASE 6!!!!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=21" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Jamming Signal</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Leif Bloomquist (Schema)</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.jammingsignal.com [206.248.167.113]</td>
<td rowspan="7" class="bbsi"><a href="images/jammingsignal1.jpg" target="_blank"><img width="165" src="images/jammingsignal1.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">EBBS 3.3</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Stock C64 with 1541 and Epyx Fastload </td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.jammingsignal.com" target="_blank" class="blueLink">http://www.jammingsignal.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Toronto Canada</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 30, 2023, 4:57 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Home of BBS Server</td>
<td class="bbse"><a href="editbbs.php?bbs_id=9" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">leagueofcommodore bbs</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">eaglewing</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">leagueofcommodore.ddns.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6401</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">ivory</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">c64c,f2k firedrive and sd2iec</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">st.louis,mo.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 24, 2022, 4:23 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=166" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Miami Vice</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">XxSwitchBladexX</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">mvbbs.dyndns.org</td>
<td rowspan="7" class="bbsi"><a href="images/mvbbs.jpg" target="_blank"><img width="165" src="images/mvbbs.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6401</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Millenium 128 BBS - Software V1.0 by Overlord.</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Desktop (PENTIUM 4 ) with 1G-RAM Winxp-PRO.</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.digitaldial.us" target="_blank" class="blueLink">http://www.digitaldial.us</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Miami, Florida</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 14, 2017, 8:28 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">BBS can be viewed in either 40 or 80 COLUMN and Can be viewed in ANSI mode</td>
<td class="bbse"><a href="editbbs.php?bbs_id=17" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">MicroMansion</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Mr.Micro</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">micromansion.kicks-ass.org</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Image BBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">CMD 40 with 1.2g Quantum upgrade and 16mb Syquest SCSI external, JiffyDos on a real C=64</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">micromansion64.com</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lemont, Il.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 14, 2017, 8:27 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Empire, SB/UD's and a friendly SYSOP, what more can a board ask for.. Come join</td>
<td class="bbse"><a href="editbbs.php?bbs_id=55" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Mother Russia</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">dabone</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">dabone.pointclark.net</td>
<td rowspan="7" class="bbsi"><a href="images/mr-40col-welcome.jpg" target="_blank"><img width="165" src="images/mr-40col-welcome.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Centipede</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128/uiec/Lantronix Wiport</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Chattanooga, TN USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 2, 2009, 10:04 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Hey Commies, come visit Mother Russia!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=37" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">My C=ult BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Maraud (Sean)</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">maraud.dynalias.com</td>
<td rowspan="7" class="bbsi"><a href="images/mycult.jpg" target="_blank"><img width="165" src="images/mycult.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">AABBS 128 12.5c</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128 and a Lt Kernal</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Florida, USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 28, 2020, 6:39 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Back Online after some hardware issues! Otherwise nonstop since 2009!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=35" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">No Name BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">hpz937</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">nonamebbs.hpz.pw</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color64 V8</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Real C64, uIEC, 1541, Swiftlink 38.4k</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">MN</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 20, 2021, 12:50 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=97" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Otherworld BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Balzabaar</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">otherworldbbs.dyndns.org</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6502</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Ivory v3.5</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Emulated C64 under WinVICE</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://otherworldbbs.dyndns.org" target="_blank" class="blueLink">http://otherworldbbs.dyndns.org</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Hemet, California, USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 19, 2014, 11:19 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=64" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Perceptual Distortion</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Fusion+</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">pd64.zapto.org</td>
<td rowspan="7" class="bbsi"><a href="images/PerceptualDistortion.jpg" target="_blank"><img width="165" src="images/PerceptualDistortion.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C*Base/F+</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64, Thunder Drive, Swiftlink</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Mexico</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 24, 2016, 11:22 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">15 UD areas 10 Sub Areas</td>
<td class="bbse"><a href="editbbs.php?bbs_id=56" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Project-SX64 BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">c4ever</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">projectsx64bbs.dynu.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6464</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color64 7.37</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">SX-64 with jiffyDOS, vic1011a rs232, CMD HD clone</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Saluda,SCli</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 10, 2018, 2:27 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">128D, CMD SuperCPU, CMD RAMLink, 2-CMD HD-40s, CMD FD-4000,Glink rs232 with BBS Server, 1mb REU</td>
<td class="bbse"><a href="editbbs.php?bbs_id=105" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Realms of Mystery</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Mystery</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.pipesup.ca</td>
<td rowspan="7" class="bbsi"><a href="images/rom-snap.png" target="_blank"><img width="165" src="images/rom-snap.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C*Base v3.x</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Ontario, Canada</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 7, 2012, 8:59 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Offline due to unexpected housing relocation. Will be back up someday. 2012-02-07</td>
<td class="bbse"><a href="editbbs.php?bbs_id=23" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Reign of Fire</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Spitfire</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">rofbbs.ddns.net</td>
<td rowspan="7" class="bbsi"><a href="images/rof.png" target="_blank"><img width="165" src="images/rof.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">CNet Amiga Pro v5.1x</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore Amiga 4000 (Emulated)</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.dxrw.org" target="_blank" class="blueLink">http://www.dxrw.org</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Dover, Tennessee, USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 14, 2017, 8:31 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Multi-Chat, Messages, Games and Warez!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=49" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Skynet BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Kazz</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">SkynetBBS.dynu.net</td>
<td rowspan="7" class="bbsi"><a href="images/2019-2-23-17-28-36-skynetbbs.png" target="_blank"><img width="165" src="images/2019-2-23-17-28-36-skynetbbs.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 version 7.3</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64 Breadbin w/JDos, Rear Admiral ThunderDrive w/sd conversion, 1571 floppy w/JDos, Sd2iEC, Glink-LT RS232 interface, 1802 monitor, 2x Commodore4Ever power supplies</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Windham, Maine</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 6, 2021, 8:36 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Offline due to a lightning strike in the spring, will be back soon as possible</td>
<td class="bbse"><a href="editbbs.php?bbs_id=135" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Surf Shop BBS #3</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Board Rider</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">ssbbs3.ddns.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6502</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Original Mod C*Base</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">WinVice/TCPSER</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Greensboro, NC</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 11, 2020, 7:08 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Original C*Base @ 19.2k!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=160" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Temporal Vortex</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Jeff Ledger</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.petscii.com</td>
<td rowspan="7" class="bbsi"><a href="images/temporalvortex.jpg" target="_blank"><img width="165" src="images/temporalvortex.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">TVBBS (Custom Software)</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.petscii.com/" target="_blank" class="blueLink">http://www.petscii.com/</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Orrville, Ohio, U.S.A.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">September 3, 2009, 10:40 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=15" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">test</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">goog</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">none</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">none</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">none</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">none</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 11, 2018, 11:40 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">none</td>
<td class="bbse"><a href="editbbs.php?bbs_id=113" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">test2</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">goog</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">none</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 12, 2018, 7:18 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=114" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">test4</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">goog</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">none</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 12, 2018, 7:18 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=115" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Age of Reason</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Gene Buckle</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">aor.retroarchive.org</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">GBBS Pro</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Apple //e</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">link</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Graham, WA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 2, 2012, 3:38 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">wow, </td>
<td class="bbse"><a href="editbbs.php?bbs_id=34" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Colosseum</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Warlock</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">colosseum.c64bbs.org</td>
<td rowspan="7" class="bbsi"><a href="images/colosseum.png" target="_blank"><img width="165" src="images/colosseum.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C*Base 3.3.7</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64, ThunderDrive, Swiftlink</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">New Jersey, USA.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">May 22, 2016, 10:51 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Laxity, Arkanix Labs Just back online after HD crash</td>
<td class="bbse"><a href="editbbs.php?bbs_id=25" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Communication Tower</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Tejekion</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">commtower.ddns.net</td>
<td rowspan="7" class="bbsi"><a href="images/comtwr.png" target="_blank"><img width="165" src="images/comtwr.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">DMBBS V4.8E+</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Vice X64, 4 Virtual CMD 4000s, SSV5.22, Emulated 2400Baud </td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">The Tennessee Valley</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">May 18, 2018, 5:03 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Down due to lack of interest.</td>
<td class="bbse"><a href="editbbs.php?bbs_id=82" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Disk Box</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Eightbitswide</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">bbs.thediskbox.com</td>
<td rowspan="7" class="bbsi"><a href="images/diskbox.png" target="_blank"><img width="165" src="images/diskbox.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Custom BBS Software</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.thediskbox.com" target="_blank" class="blueLink">http://www.thediskbox.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">NE Ohio</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 9, 2021, 4:17 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=98" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">the league of commodore</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">leagueman</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">tloc2.ddns.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6464</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">ivory bbs all running on a sd2iec device</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">c64c,1541,jiffydos inside,sd2iec with rs232 userport adapter</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">st.louis,missouri</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 5, 2018, 12:27 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">New C64 BBS!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=85" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">the league of commodore</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">eaglewing</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">tlocbbs.ddns.net</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6401</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">color64 v7.37</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">c64c,sd2iec,rearadmiral fd2000k floppy drive,nullmodem cable with rs232 userport adapter 32inch hdtv monitor</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">st.louis,mo.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">January 12, 2021, 7:12 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=112" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Pirates Cove</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Blackbeard</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">pc.servebbs.org</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6464</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">C-Net 128 Unreleased version</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Commodore 128, Commodore 1902a, Commodore 1571, Commodore 1581, CMD Thunderdrive 4.1 Gig, Turbo RS232, Jiffy DOS</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Long Island, NY</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 25, 2021, 8:52 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Running on real Commodore equipment with a never released version of C-Net 128</td>
<td class="bbse"><a href="editbbs.php?bbs_id=119" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The PUB</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Wirewolf</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">Dial up</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">Dial-up!</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color64BBS v7.37 (registered)</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64C, RA Thunderdrive, Supra 2400</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Lacey, Washington</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 16, 2018, 7:28 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">RETRO! Dial up only! 24/7 1-360-491-0482 </td>
<td class="bbse"><a href="editbbs.php?bbs_id=96" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The SID Station BBS</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Fritske</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">tssbbs.servebeer.com</td>
<td rowspan="7" class="bbsi"><a href="images/sidstation.png" target="_blank"><img width="165" src="images/sidstation.png"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Ivory BBS,bbs server</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C128 in C64, 2 1541 Drives, strikelink, old crappy laptop, power cartridge</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://c64radio.com" target="_blank" class="blueLink">http://c64radio.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">Belgium</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">February 10, 2016, 6:07 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=73" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Slayer Within</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Smokin Girl</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">ssmokingirl.ath.cx</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Ivory BBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 14, 2010, 12:11 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=47" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">The Underground Domain</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Alwyz</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">udi.dyndns.tv</td>
<td rowspan="7" class="bbsi"><a href="images/udibbs.jpg" target="_blank"><img width="165" src="images/udibbs.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">6400</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Centipede 128</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">WinVice 128 / TCPSER / 38.4k baud</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://1200baud.wordpress.com/category/udi-bbs-news/" target="_blank" class="blueLink">http://1200baud.wordpress.com/category/udi-bbs-news/</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">NYC</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">April 4, 2015, 3:45 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Back online and better than ever! NTSC Scene BBS / Exclusive UDI Release Portal. Petscii Collections. Over 1000 textfiles. 120 gigs storage. HS Xfers! 40/80. Ansi Support!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=53" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">THE VOiD</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Terra-X</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">thevoid.servebbs.org</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Mystic</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">Dell Poweredge 1800 4TB drive space</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">USA</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">May 22, 2016, 9:09 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Only C= bbs's on the site please. Sorry, changing to offline</td>
<td class="bbse"><a href="editbbs.php?bbs_id=87" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Torture Chamber</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Hawk</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">Maryland</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">Dial-up!</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">CMBBS</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64, multiple 3.5 drives and external hard drives</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">December 19, 2018, 8:16 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Alas. Those were the days. </td>
<td class="bbse"><a href="editbbs.php?bbs_id=130" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Unauthorised Access</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">Phantasm</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">uabbs.servebbs.com</td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color64 v8.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64-EMU</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">U.K.</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 8, 2008, 12:53 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=24" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Wizard's Realm</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd">WizardNJ</td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd">wizbbs.c64bbs.org</td>
<td rowspan="7" class="bbsi"><a href="images/wizbbs.jpg" target="_blank"><img width="165" src="images/wizbbs.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd">Color 64 v8.0</td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd">C64, JIFFYDOS, CMD HD, TURBO232 @ 38400</td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"><a href="http://www.wizardsrealmbbs.com" target="_blank" class="blueLink">http://www.wizardsrealmbbs.com</a></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd">NewJersey</td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">August 28, 2015, 10:39 pm</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd">Just back online after a while here to stay!!!!</td>
<td class="bbse"><a href="editbbs.php?bbs_id=5" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Y</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd"></td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">Dial-up!</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 19, 2016, 10:24 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=77" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">Z</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd"></td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">Dial-up!</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">November 19, 2016, 10:24 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=78" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
<table class="bbs">
<tr>
<td class="bbsh">BBS Name:</td>
<td class="bbsd">z</td>
<td rowspan="2" class="bbss" bgcolor='#ff3300'>Status: Offline</td>
</tr>
<tr>
<td class="bbsh">Sysop:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Address:</td>
<td class="bbsd"></td>
<td rowspan="7" class="bbsi"><a href="images/noimage.jpg" target="_blank"><img width="165" src="images/noimage.jpg"></a></td>
</tr>
<tr>
<td class="bbsh">Port:</td>
<td class="bbsd">23</td>
</tr>
<tr>
<td class="bbsh">BBS Software:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Hardware:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Website:</td>
<td class="bbsd">None</td>
</tr>
<tr>
<td class="bbsh">Location:</td>
<td class="bbsd"></td>
</tr>
<tr>
<td class="bbsh">Listing Updated:</td>
<td class="bbsd">July 23, 2019, 2:23 am</td>
</tr>
<tr>
<td class="bbsh">Comments:</td>
<td class="bbsd"></td>
<td class="bbse"><a href="editbbs.php?bbs_id=140" class="blueLink">Edit Listing</a></td>
</tr>
</table><br>
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<center><font color="#FF9900"><font size=+2>Welcome to the Kid Icarus Shrine!</font></font>
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<p><font color="#FFCC33">Kid Icarus is one of my favorite NES games. I
played it a lot and I beat it quite a few times! It is often called the
"companion" game to Metroid, and the two games do share a similar graphic
and music style. Unlike Metroid, Kid Icarus's setting is not outer space,
but a mythcial world based somewhat in part on Greek mythology. (Although,
many of the monsters are unlike anything you've ever seen before!) It has
that same sort of dark and gloomy atmosphere of Metroid, which sort of
gives it a "gothic" feeling. Kid Icarus is also one of the most difficult
games for the NES. This shrine is meant to showcase one of my favorite
and most unusual games.
<p><center><a href="../gameshrines.html"><B>BACK TO GAME SHRINES</a></center>
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Kid Icarus Shrine
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Welcome to the Kid Icarus Shrine!
Kid Icarus is one of my favorite NES games. I
played it a lot and I beat it quite a few times! It is often called the
"companion" game to Metroid, and the two games do share a similar graphic
and music style. Unlike Metroid, Kid Icarus's setting is not outer space,
but a mythcial world based somewhat in part on Greek mythology. (Although,
many of the monsters are unlike anything you've ever seen before!) It has
that same sort of dark and gloomy atmosphere of Metroid, which sort of
gives it a "gothic" feeling. Kid Icarus is also one of the most difficult
games for the NES. This shrine is meant to showcase one of my favorite
and most unusual games.
[**BACK TO GAME SHRINES**](../gameshrines.html)
[**BACK TO MAIN PAGE**](../index.html)
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<meta name="Author" content="Margaret DeAngelis">
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<title>Ron's Pond Scum</title>
</head>
<body background="http://www.silkentent.com/gus1911/MainBck.jpg">
<center><font face="CentSchBook MT"><font color="#3366FF"><font size=+4><b>Ron's
Pond Scum</b></font></font></font>
<br>
<br>
<img SRC="http://www.silkentent.com/gus1911/PondDistant00.jpg" height=286 width=406>
<p><font face="CentSchBook MT"><font color="#009900"><font size=+3><b>An Adventure
in Protozoan Art</b>
<br>
<center><img SRC="http://www.silkentent.com/gus1911/BlueStentOne.jpg" height=130 width=172></center>
<font color="4A766E">The Creatures That Live in Your Pond</font></font></font>
<p><font face="CentSchBook MT"><font color="#3366FF"><font size=+2>Come on in,
the water's fine!! The following pics were taken through my <a href="http://www.microscopeworld.com/"><font color="#4A766E"><b>microscope</b></font></a> using a digital camera. Specimens were from my backyard pond.</font></font></font>
<p>
<p><font face="CentSchBook MT"><font color="#3366FF"><font size=+2>____________ * * * * * * * * * * * * * * * ____________</font></font></font></font>
<p>
<br>
<center><font face="CentSchBook MT"><font color="#000000"><font size=+1><i>
<b>Use your browser's "Back" button to return to this page</font></font></font></i></b>
<p>
<br><font face="CentSchBook MT"><font color="#aa0000"><font size=+1>
<center><b><i>The Paramecium - The Most Studied Of All The Protozoa.
<center>Click on the links at the end of this page, <font color="#4A766E">"Size"</font> and <font color="#4A766E">"Facts and Trivia"</font>, to learn more about the Paramecium.</center>
</b></i></center></font></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Paramecium.htm">Paramecium caudatum</a>, an image of one of the more common Paramecium types and one of the smaller varieties, growing to about 125 microns in size.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Pbursaria.htm">Paramecium bursaria</a>, a species of Paramecium that appears green because of the presence of symbiotic Zoochlorella.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">This image shows in unusual color the intricate details of this amazing one celled animal - the <a href="http://www.silkentent.com/gus1911/ParameciumSp.htm">Paramecium</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Dividing.htm">Click here to see an image of a Paramecium dividing.</a></font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Paramecia have a defense system that they can deploy when attacked or when they feel threatened.<a href="http://www.silkentent.com/gus1911/ParaDefense.htm"> Click here to find out more.</a></font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">All ciliates also can multiply by a process known as <b><i>conjugation.</i></b> Here is a rare image of two Paramecium <a href="http://www.silkentent.com/gus1911/ParameciumConj.htm">engaged in true sexual reproduction.</a></font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Get a real sense of the size of these critters. Click on this link to see a swarm of <a href="http://www.silkentent.com/gus1911/ParaSwarm.htm">Paramecium inside a speck of water</a> that is smaller than the "period" on your keyboard's "period key".</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#aa0000"><font size=+1>
<center><b><i>The Actinopods</b></i></center></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Actinosphaerium.htm">Actinosphaerium (or an Actinophyrs)</a>. The spikes are used to spear other protozoa. The protoplasmic "soup" is then sucked out of the victim into a food vacuole where it is digested.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">An excellent image of an <a href="http://www.silkentent.com/gus1911/ActAfterLunch.htm">Actinophyrs </a>digesting a meal.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">An excellent image of an <a href="http://www.silkentent.com/gus1911/ActinoLg.htm">Actinosphaerium</a>. Actinosphaerium can grow up to 1,000 microns in size. This specimen certainly is close to that figure.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">An image of <a href="http://www.silkentent.com/gus1911/3Protos.htm">three different Protozoa</a>, all in a space not much bigger than a pin head.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#aa0000"><font size=+1>
<center><b><i>Some Images of the Interesting Vorticella</b></i></center></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Vorticella.htm">Vorticella</a>. Cilia create currents in the water to draw food into the Vorticella's huge anterior opening. Bits of ingested food are clearly visible. Because the cilia are constantly moving, they are blurred in the photo but still visible.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">There are in excess of 100 species of <a href="http://www.silkentent.com/gus1911/VorticellaB.htm">Vorticella</a>. Here is an image of a species that clearly shows all of the creature's internal parts and functions.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Another image of a <a href="http://www.silkentent.com/gus1911/Vorticella2.htm">Vorticella</a>. The trailing stalk is faintly visible in this photo. See the picture along with a description of the Vorticella's unusual behavior.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">I had to follow these five Vorticella around for several minutes before they settled in one spot. <a href="http://www.silkentent.com/gus1911/5Vorticella.htm">Click here to see what happens when they're startled</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Click on this link to see a bit of misfortune that befell an inattentive <a href="http://www.silkentent.com/gus1911/VortNoStalk.htm">Vorticella</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is an image of a <a href="http://www.silkentent.com/gus1911/VortDividing.htm">Vorticella dividing</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#aa0000"><font size=+1>
<center><b><i>Some Common and Not So Common Stentor</b></i></center></font></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000">Here's a protozoa that appears quite different from a Vorticella but has many of the same behavior and feeding patterns, the <a href="http://www.silkentent.com/gus1911/Stentor.htm">Stentor</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">This is an excellent image of two Stentor. <a href="http://www.silkentent.com/gus1911/StentorTwo.htm"> Look here</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">The <a href="http://www.silkentent.com/gus1911/StentBunch.htm">Stentor</a> is not a communal creature, but it is possible to encourage them to "huddle" together. Click on the link.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">The Stentor provides many opportunities for capturing some interesting images. <a href="http://www.silkentent.com/gus1911/StentClost.htm">Here's a Stentor consuming a single celled Closterium</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is an image of two Stentor that you <a href="http://www.silkentent.com/gus1911/BlueStent.htm">Must See</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is an image of a blue Stentor showing the large, fully extended mouth opening and the surrounding cilia. <a href="http://www.silkentent.com/gus1911/BlueStentOne.htm">Click Here</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">I continue to find interesting specimens of the Blue Stentor. <a href="http://www.silkentent.com/gus1911/BlueStentComp.htm">Here is a composite image</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">This one celled Protozoan continues to show its many fascinating faces. <a href="http://www.silkentent.com/gus1911/BlueStentOneB.htm">Two more images of the Blue Stentor</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#aa0000"><font size=+1>
<center><b><i>Crustaceans (Free Living Copepods)</b></i></center></font></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000">Crustaceans are abundant in ponds and are easily spotted once the water warms. The microscopic ones feed on algae, decaying matter, other protozoa and even bacteria.
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here's a picture of a common crustacean - a Chydorus, a relative of the Daphnia. A dead <a href="http://www.silkentent.com/gus1911/DaphniaWorm.htm">Chydorus</a>,</font></font></font> but one worth a look anyway. You'll see why.
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here's an image of a copepod that doesn't look like a copepod, nor is it free living. It's a parasitic <a href="http://www.silkentent.com/gus1911/Anchor.htm">Anchor Worm</a>. </font></font></font> Unfortunately, for the fish from which it was removed, its head remained in the fish.
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is another species of <a href="http://www.silkentent.com/gus1911/AnchorWormLive.htm">Anchor Worm</a>, </font></font></font> commonly called a skin fluke or gill fluke.
<p>
<font face="CentSchBook MT"><font color="#aa0000"><font size=+2>
<p>
<center><b>* * * * * * * * * * * * * * *</b></center></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000">When looking for protozoa one wouldn't expect to see anything colorful, since 99% of these microbes are transparent. Click on this link for a pic of a red-colored, and not often seen <a href="http://www.silkentent.com/gus1911/Blepharisma2.htm">Blepharisma</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Another picture of a <a href="http://www.silkentent.com/gus1911/Blepharisma.htm">Blepharisma</a>. Click here for a better view of its natural shape and a few of its more prominent features.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">The life of a microbe in a pond isn't all fun and games, or eat and sleep. <a href="http://www.silkentent.com/gus1911/Dinner.htm">Click here to see how bad things can be</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is common pond creature - a Holotrich, and most likely a <a href="http://www.silkentent.com/gus1911/Dileptus.htm">Dileptus species</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/HodgePodge.htm">A drop of water from our birdbath</a> contains an assortment of different microbes.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Culture.htm">A water drop teeming with micro life</a>, some as small as 1 or 2 microns. This culture was made by allowing dried leaves and grass to decay in the open air.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">An <a href="http://www.silkentent.com/gus1911/ActCol.htm">Actinosphaerium and a Colurella</a> together. I watched the two of them bump into each other for several minutes and neither one seemed to be bothered by the other. Apparently they aren't part of each other's diet.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#aa0000"><font size=+1>
<center><b><i>Worms and Fly Larvae</b></i></center></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000">Any pond or pond filter will contain a variety of worms. Many of these wrigglers are the larvae of the many different kinds of flies and midges that hang around backyard ponds and ornamental waterfalls, while some are true aquatic worms. A few are visible, such as the bloodworms that we frequently see in our filter systems. Many, however, are microscopic. Click here to see the <a href="http://www.silkentent.com/gus1911/BlobWorm.htm">one worm that must be one of the ugliest and most repulsive in all of wormdom.</a></font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here's an image of a fly larva that takes up residence in the busiest part of the pond. <a href="http://www.silkentent.com/gus1911/UWorm.htm">Click here to see why and how.</a></font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Glassworms, Bloodworms and Ghostworms are all the larvae of the many different kinds of black flies (midges) that we see around our ponds. <a href="http://www.silkentent.com/gus1911/BlackFlySeq.htm">Click here to see a Bloodworm and an image of the pupa.</a></font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">This image is a sequel to the preceeding image. <a href="http://www.silkentent.com/gus1911/Scavengers.htm">Click here to see the scavengers that have moved in on the remains.</a></font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#aa0000"><font size=+1>
<center><b><i>Amoebas</b></i></center></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000">Amoebas are amorphous so they are seen in a variety of shapes and sizes. They also have developed a variety of ways to cope with the dangers of their environment. Click here to see an image of an <a href="http://www.silkentent.com/gus1911/Arcella.htm">Arcella</a>, an Amoeba that has developed an unusual method of protection.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is another species of <a href="http://www.silkentent.com/gus1911/ShelledAmoeba.htm">Shelled Amoeba</a>. Unlike the Arcella in the previous image, this species clearly shows the gritty, granular composition of the domed shell.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is a composite picture of two Shelled Amoebas, both taken from the same water drop. Note the differences in the shell composition, and the evidence of some structural failure on one of them.<a href="http://www.silkentent.com/gus1911/ShelledCompo.htm"> Click here</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Click here to see an <a href="http://www.silkentent.com/gus1911/Amoeba.htm">Amoeba</a> the way we always imagined one would look - like an amorphous, protoplasmic "splat".</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here are two images of another naked amoeba, probably an <a href="http://www.silkentent.com/gus1911/Amoeba2.htm">Amoeba proteus</a>, taken just a few seconds apart.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is a closer view of the same <a href="http://www.silkentent.com/gus1911/AmoebaBranch.htm">Amoeba</a> that appears in the previous image.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#aa0000"><font size=+1>
<center><b><i>Multicelled Microlife</b></i></center></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000">A common species of <a href="http://www.silkentent.com/gus1911/Rotaria.htm">Rotifer</a>. Rotifers can be found wherever there is water or moisture - ponds, puddles, damp ground or mosses. They are included in the small-sized group of pond critters, but are easily seen even under low power. There are many varieties and their varied methods of locomotion are interesting to observe. They are usually found on the pond bottom.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Another good place to look for Rotifers is the outdoor bird bath, preferably one that hasn't been cleaned in a week or so. <a href="http://www.silkentent.com/gus1911/BirdBath.htm">Click here</a> to see a colony of them.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is an unusually detailed and clear image of another species of Rotifer.<a href="http://www.silkentent.com/gus1911/RotandEgg.htm"> Click here</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Mite.htm">Water Mites</a> can be difficult to identify because they are so abundant and varied in appearance. This critter was originally mis-identified as a water mite but in fact is a Cyclops, quite common as both a marine and freshwater species. Click to find out more about these interesting creatures.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Mite2.htm">Click here</a> for an image of a true water Water Mite, and some additional information about microanimals.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Gastro.htm">Gastrotrichs</a> are frequent vistors to any backyard pond. They, too, are members of the multicellular Animal Kingdom.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is a pic of a microbe from a group of creatures that includes at least four families, thirty genera and numerous species.
<a href="http://www.silkentent.com/gus1911/Stylonychia.htm">Have a look.</a>
</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#aa0000"><font size=+1>
<center><b><i>Algae, or Green Protists</b></i></center></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000">Here is an image of what appears to be algae, but really isn't. I included it here because it is readily known by its common name - <a href="http://www.silkentent.com/gus1911/StringAlgae.htm">Blue/Green Algae</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is another image of a Blue/Green Algae - likewise, not an algae but one of the many species of <a href="http://www.silkentent.com/gus1911/Cyano.htm">Cyanobacteria</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here are two excellent images of <a href="http://www.silkentent.com/gus1911/ClassicString.htm">String Algae</a>.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Brush.htm">This Algae</a> can cause serious problems if you don't pay attention to your maintenance duties.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Closterium.htm">Closterium</a>. An interesting Green Protist - easy to spot and quite common in healthy ponds and lakes.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000"><a href="http://www.silkentent.com/gus1911/Selenastrum.htm">Selenastrum and Pediastrium</a>, two interesting Green Protists. Common in quiet waters, and sometimes found in wet soils and sands.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">An unusually clear image of two clusters of <a href="http://www.silkentent.com/gus1911/Pediastrium.htm">Pediastrium</a>. </font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Some large clusters of <a href="http://www.silkentent.com/gus1911/Selenastrum2.htm">Selenastrum</a>. Pediastrium and Selenastrum are just two of the many single cell colonial Protists that give us our dreaded green pond water.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">A scraping from one of my lily stems yielded an <a href="http://www.silkentent.com/gus1911/AssortedAlgae.htm">assortment of different Algae</a>. More than I can identify.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">Here is an image of a cluster of <a href="http://www.silkentent.com/gus1911/Diatoms.htm">Diatoms</a>. They aren't green protists but I've included them here because they are often found in areas where algae is also found.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">This image is from the same salt water tank showing several other types of <a href="http://www.silkentent.com/gus1911/Diatoms2.htm">Diatoms</a>. This image was taken at the same magnification as the previous one so the relative sizes can be compared. These were squeezed from the sponge filter. Note the perfect symmetry of the specimens as well as the interesting coloration of the Diatom in the upper right of the image. </font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#aa0000"><font size=+1>
<center><b><i>Animal, Vegetable or Mineral? The Unidentifieds</b></i></center></font></font></font>
<br><font face="CentSchBook MT"><font color="#000000">This creature, for the moment, is <a href="http://www.silkentent.com/gus1911/GiantAmoeba.htm">unidentified</a>. It's about 1,000 microns in size, and I found dozens in a container of pond water that I allowed to become stagnant and polluted.</font></font></font>
<p>
<br><font face="CentSchBook MT"><font color="#000000">This specimen is large, at least 1,000 microns across, perhaps larger. It was an "unidentified" for quite some time until I was sent a photograph of its twin brother by someone visiting my site. It's a Bryozoa. There is an extensive fossil record of these multicelled critters. They are found in both fresh and sea water and they feed through cilia that cover their bodies. <a href="http://www.silkentent.com/gus1911/Unidentified1.htm">It's an interesting specimen under the microscope</a>.</font></font></font>
<p>
<p>
<br><font face="CentSchBook MT"><font color="#3366FF"><font size=+1><a href="http://www.silkentent.com/gus1911/SizeText.htm">A Few Words About Size</font></font></font>
<br><font face="CentSchBook MT"><font color="#3366FF"><font size=+1><a href="http://www.silkentent.com/gus1911/StuffText.htm">Interesting Facts and Trivia that Everyone Should Know</font></font></font>
<br>
<br>
<font face="CentSchBook MT"><font size=+1><a href="http://www.microscopy-uk.org.uk/mag/wimsmall/small.html"><i><b>Specimen Backgrounds Courtesy of Wim von Egmond. Click Here for Wim's Marvelous Site</i></b></font></font></font>
<br>
<br>
<font face="CentSchBook MT"><font color="#3366FF"><font size=+1><a
href="http://www.aunet.com.au/microscopes.htm"><i><b>Click Here For Another Source For Quality Microscopes, Australia Based</i></b></font>
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<font face="CentSchBook MT"><font size=+1><a href="http://microscope-microscope.org/applications/pond-critters/pond-critters.htm"><b><i>Click Here For - Pond Critters, An Illustrated Guide</i></b></font></font></font></font>
<p>
<p>
<a href="mailto:fingal2@comcast.net">Ron DeAngelis</a></font></font></font> - Pond Scum Developer, Owner
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Ron's Pond Scum
**Ron's
Pond Scum**
![](http://www.silkentent.com/gus1911/PondDistant00.jpg)
**An Adventure
in Protozoan Art**
![](http://www.silkentent.com/gus1911/BlueStentOne.jpg)
The Creatures That Live in Your Pond
Come on in,
the water's fine!! The following pics were taken through my [**microscope**](http://www.microscopeworld.com/) using a digital camera. Specimens were from my backyard pond.
\_\_\_\_\_\_\_\_\_\_\_\_ \* \* \* \* \* \* \* \* \* \* \* \* \* \* \* \_\_\_\_\_\_\_\_\_\_\_\_
***Use your browser's "Back" button to return to this page***
***The Paramecium - The Most Studied Of All The Protozoa.
Click on the links at the end of this page, "Size" and "Facts and Trivia", to learn more about the Paramecium.***
[Paramecium caudatum](http://www.silkentent.com/gus1911/Paramecium.htm), an image of one of the more common Paramecium types and one of the smaller varieties, growing to about 125 microns in size.
[Paramecium bursaria](http://www.silkentent.com/gus1911/Pbursaria.htm), a species of Paramecium that appears green because of the presence of symbiotic Zoochlorella.
This image shows in unusual color the intricate details of this amazing one celled animal - the [Paramecium](http://www.silkentent.com/gus1911/ParameciumSp.htm).
[Click here to see an image of a Paramecium dividing.](http://www.silkentent.com/gus1911/Dividing.htm)
Paramecia have a defense system that they can deploy when attacked or when they feel threatened. [Click here to find out more.](http://www.silkentent.com/gus1911/ParaDefense.htm)
All ciliates also can multiply by a process known as ***conjugation.*** Here is a rare image of two Paramecium [engaged in true sexual reproduction.](http://www.silkentent.com/gus1911/ParameciumConj.htm)
Get a real sense of the size of these critters. Click on this link to see a swarm of [Paramecium inside a speck of water](http://www.silkentent.com/gus1911/ParaSwarm.htm) that is smaller than the "period" on your keyboard's "period key".
***The Actinopods***
[Actinosphaerium (or an Actinophyrs)](http://www.silkentent.com/gus1911/Actinosphaerium.htm). The spikes are used to spear other protozoa. The protoplasmic "soup" is then sucked out of the victim into a food vacuole where it is digested.
An excellent image of an [Actinophyrs](http://www.silkentent.com/gus1911/ActAfterLunch.htm) digesting a meal.
An excellent image of an [Actinosphaerium](http://www.silkentent.com/gus1911/ActinoLg.htm). Actinosphaerium can grow up to 1,000 microns in size. This specimen certainly is close to that figure.
An image of [three different Protozoa](http://www.silkentent.com/gus1911/3Protos.htm), all in a space not much bigger than a pin head.
***Some Images of the Interesting Vorticella***
[Vorticella](http://www.silkentent.com/gus1911/Vorticella.htm). Cilia create currents in the water to draw food into the Vorticella's huge anterior opening. Bits of ingested food are clearly visible. Because the cilia are constantly moving, they are blurred in the photo but still visible.
There are in excess of 100 species of [Vorticella](http://www.silkentent.com/gus1911/VorticellaB.htm). Here is an image of a species that clearly shows all of the creature's internal parts and functions.
Another image of a [Vorticella](http://www.silkentent.com/gus1911/Vorticella2.htm). The trailing stalk is faintly visible in this photo. See the picture along with a description of the Vorticella's unusual behavior.
I had to follow these five Vorticella around for several minutes before they settled in one spot. [Click here to see what happens when they're startled](http://www.silkentent.com/gus1911/5Vorticella.htm).
Click on this link to see a bit of misfortune that befell an inattentive [Vorticella](http://www.silkentent.com/gus1911/VortNoStalk.htm).
Here is an image of a [Vorticella dividing](http://www.silkentent.com/gus1911/VortDividing.htm).
***Some Common and Not So Common Stentor***
Here's a protozoa that appears quite different from a Vorticella but has many of the same behavior and feeding patterns, the [Stentor](http://www.silkentent.com/gus1911/Stentor.htm).
This is an excellent image of two Stentor. [Look here](http://www.silkentent.com/gus1911/StentorTwo.htm).
The [Stentor](http://www.silkentent.com/gus1911/StentBunch.htm) is not a communal creature, but it is possible to encourage them to "huddle" together. Click on the link.
The Stentor provides many opportunities for capturing some interesting images. [Here's a Stentor consuming a single celled Closterium](http://www.silkentent.com/gus1911/StentClost.htm).
Here is an image of two Stentor that you [Must See](http://www.silkentent.com/gus1911/BlueStent.htm).
Here is an image of a blue Stentor showing the large, fully extended mouth opening and the surrounding cilia. [Click Here](http://www.silkentent.com/gus1911/BlueStentOne.htm).
I continue to find interesting specimens of the Blue Stentor. [Here is a composite image](http://www.silkentent.com/gus1911/BlueStentComp.htm).
This one celled Protozoan continues to show its many fascinating faces. [Two more images of the Blue Stentor](http://www.silkentent.com/gus1911/BlueStentOneB.htm).
***Crustaceans (Free Living Copepods)***
Crustaceans are abundant in ponds and are easily spotted once the water warms. The microscopic ones feed on algae, decaying matter, other protozoa and even bacteria.
Here's a picture of a common crustacean - a Chydorus, a relative of the Daphnia. A dead [Chydorus](http://www.silkentent.com/gus1911/DaphniaWorm.htm),
but one worth a look anyway. You'll see why.
Here's an image of a copepod that doesn't look like a copepod, nor is it free living. It's a parasitic [Anchor Worm](http://www.silkentent.com/gus1911/Anchor.htm).
Unfortunately, for the fish from which it was removed, its head remained in the fish.
Here is another species of [Anchor Worm](http://www.silkentent.com/gus1911/AnchorWormLive.htm), commonly called a skin fluke or gill fluke.
**\* \* \* \* \* \* \* \* \* \* \* \* \* \* \***
When looking for protozoa one wouldn't expect to see anything colorful, since 99% of these microbes are transparent. Click on this link for a pic of a red-colored, and not often seen [Blepharisma](http://www.silkentent.com/gus1911/Blepharisma2.htm).
Another picture of a [Blepharisma](http://www.silkentent.com/gus1911/Blepharisma.htm). Click here for a better view of its natural shape and a few of its more prominent features.
The life of a microbe in a pond isn't all fun and games, or eat and sleep. [Click here to see how bad things can be](http://www.silkentent.com/gus1911/Dinner.htm).
Here is common pond creature - a Holotrich, and most likely a [Dileptus species](http://www.silkentent.com/gus1911/Dileptus.htm).
[A drop of water from our birdbath](http://www.silkentent.com/gus1911/HodgePodge.htm) contains an assortment of different microbes.
[A water drop teeming with micro life](http://www.silkentent.com/gus1911/Culture.htm), some as small as 1 or 2 microns. This culture was made by allowing dried leaves and grass to decay in the open air.
An [Actinosphaerium and a Colurella](http://www.silkentent.com/gus1911/ActCol.htm) together. I watched the two of them bump into each other for several minutes and neither one seemed to be bothered by the other. Apparently they aren't part of each other's diet.
***Worms and Fly Larvae***
Any pond or pond filter will contain a variety of worms. Many of these wrigglers are the larvae of the many different kinds of flies and midges that hang around backyard ponds and ornamental waterfalls, while some are true aquatic worms. A few are visible, such as the bloodworms that we frequently see in our filter systems. Many, however, are microscopic. Click here to see the [one worm that must be one of the ugliest and most repulsive in all of wormdom.](http://www.silkentent.com/gus1911/BlobWorm.htm)
Here's an image of a fly larva that takes up residence in the busiest part of the pond. [Click here to see why and how.](http://www.silkentent.com/gus1911/UWorm.htm)
Glassworms, Bloodworms and Ghostworms are all the larvae of the many different kinds of black flies (midges) that we see around our ponds. [Click here to see a Bloodworm and an image of the pupa.](http://www.silkentent.com/gus1911/BlackFlySeq.htm)
This image is a sequel to the preceeding image. [Click here to see the scavengers that have moved in on the remains.](http://www.silkentent.com/gus1911/Scavengers.htm)
***Amoebas***
Amoebas are amorphous so they are seen in a variety of shapes and sizes. They also have developed a variety of ways to cope with the dangers of their environment. Click here to see an image of an [Arcella](http://www.silkentent.com/gus1911/Arcella.htm), an Amoeba that has developed an unusual method of protection.
Here is another species of [Shelled Amoeba](http://www.silkentent.com/gus1911/ShelledAmoeba.htm). Unlike the Arcella in the previous image, this species clearly shows the gritty, granular composition of the domed shell.
Here is a composite picture of two Shelled Amoebas, both taken from the same water drop. Note the differences in the shell composition, and the evidence of some structural failure on one of them. [Click here](http://www.silkentent.com/gus1911/ShelledCompo.htm).
Click here to see an [Amoeba](http://www.silkentent.com/gus1911/Amoeba.htm) the way we always imagined one would look - like an amorphous, protoplasmic "splat".
Here are two images of another naked amoeba, probably an [Amoeba proteus](http://www.silkentent.com/gus1911/Amoeba2.htm), taken just a few seconds apart.
Here is a closer view of the same [Amoeba](http://www.silkentent.com/gus1911/AmoebaBranch.htm) that appears in the previous image.
***Multicelled Microlife***
A common species of [Rotifer](http://www.silkentent.com/gus1911/Rotaria.htm). Rotifers can be found wherever there is water or moisture - ponds, puddles, damp ground or mosses. They are included in the small-sized group of pond critters, but are easily seen even under low power. There are many varieties and their varied methods of locomotion are interesting to observe. They are usually found on the pond bottom.
Another good place to look for Rotifers is the outdoor bird bath, preferably one that hasn't been cleaned in a week or so. [Click here](http://www.silkentent.com/gus1911/BirdBath.htm) to see a colony of them.
Here is an unusually detailed and clear image of another species of Rotifer. [Click here](http://www.silkentent.com/gus1911/RotandEgg.htm).
[Water Mites](http://www.silkentent.com/gus1911/Mite.htm) can be difficult to identify because they are so abundant and varied in appearance. This critter was originally mis-identified as a water mite but in fact is a Cyclops, quite common as both a marine and freshwater species. Click to find out more about these interesting creatures.
[Click here](http://www.silkentent.com/gus1911/Mite2.htm) for an image of a true water Water Mite, and some additional information about microanimals.
[Gastrotrichs](http://www.silkentent.com/gus1911/Gastro.htm) are frequent vistors to any backyard pond. They, too, are members of the multicellular Animal Kingdom.
Here is a pic of a microbe from a group of creatures that includes at least four families, thirty genera and numerous species.
[Have a look.](http://www.silkentent.com/gus1911/Stylonychia.htm)
***Algae, or Green Protists***
Here is an image of what appears to be algae, but really isn't. I included it here because it is readily known by its common name - [Blue/Green Algae](http://www.silkentent.com/gus1911/StringAlgae.htm).
Here is another image of a Blue/Green Algae - likewise, not an algae but one of the many species of [Cyanobacteria](http://www.silkentent.com/gus1911/Cyano.htm).
Here are two excellent images of [String Algae](http://www.silkentent.com/gus1911/ClassicString.htm).
[This Algae](http://www.silkentent.com/gus1911/Brush.htm) can cause serious problems if you don't pay attention to your maintenance duties.
[Closterium](http://www.silkentent.com/gus1911/Closterium.htm). An interesting Green Protist - easy to spot and quite common in healthy ponds and lakes.
[Selenastrum and Pediastrium](http://www.silkentent.com/gus1911/Selenastrum.htm), two interesting Green Protists. Common in quiet waters, and sometimes found in wet soils and sands.
An unusually clear image of two clusters of [Pediastrium](http://www.silkentent.com/gus1911/Pediastrium.htm).
Some large clusters of [Selenastrum](http://www.silkentent.com/gus1911/Selenastrum2.htm). Pediastrium and Selenastrum are just two of the many single cell colonial Protists that give us our dreaded green pond water.
A scraping from one of my lily stems yielded an [assortment of different Algae](http://www.silkentent.com/gus1911/AssortedAlgae.htm). More than I can identify.
Here is an image of a cluster of [Diatoms](http://www.silkentent.com/gus1911/Diatoms.htm). They aren't green protists but I've included them here because they are often found in areas where algae is also found.
This image is from the same salt water tank showing several other types of [Diatoms](http://www.silkentent.com/gus1911/Diatoms2.htm). This image was taken at the same magnification as the previous one so the relative sizes can be compared. These were squeezed from the sponge filter. Note the perfect symmetry of the specimens as well as the interesting coloration of the Diatom in the upper right of the image.
***Animal, Vegetable or Mineral? The Unidentifieds***
This creature, for the moment, is [unidentified](http://www.silkentent.com/gus1911/GiantAmoeba.htm). It's about 1,000 microns in size, and I found dozens in a container of pond water that I allowed to become stagnant and polluted.
This specimen is large, at least 1,000 microns across, perhaps larger. It was an "unidentified" for quite some time until I was sent a photograph of its twin brother by someone visiting my site. It's a Bryozoa. There is an extensive fossil record of these multicelled critters. They are found in both fresh and sea water and they feed through cilia that cover their bodies. [It's an interesting specimen under the microscope](http://www.silkentent.com/gus1911/Unidentified1.htm).
[A Few Words About Size](http://www.silkentent.com/gus1911/SizeText.htm)
[Interesting Facts and Trivia that Everyone Should Know](http://www.silkentent.com/gus1911/StuffText.htm)
[***Specimen Backgrounds Courtesy of Wim von Egmond. Click Here for Wim's Marvelous Site***](http://www.microscopy-uk.org.uk/mag/wimsmall/small.html)
[***Click Here For Another Source For Quality Microscopes, Australia Based***](http://www.aunet.com.au/microscopes.htm)
[***Click Here For - Pond Critters, An Illustrated Guide***](http://microscope-microscope.org/applications/pond-critters/pond-critters.htm)
[Ron DeAngelis](mailto:fingal2@comcast.net) - Pond Scum Developer, Owner
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</center>
<ul>
<li><a href="#news"><b><font color="purple">In the News</font></b></a></li>
<li><a href="#research"><b><font color="blue">Research</font></b></a></li>
<li><a href="#research"><b><font color="blue">Demos</font></b></a></li>
<li><a href="#hlsim"><b><font color="blue">HLSIM</font></b></a></li>
<li>
<a href="paperlisting.html"><b><font color="blue">Publications
</font></b></a>
</li>
<li>
<a href="/projects/mac/mac-people.html"><b><font color="blue">People
</font></b></a>
</li>
<li>
<a href="related_sites.html"><b><font color="blue">Related Sites
</font></b></a>
</li>
</ul>
<center>
<img src="Tube/tube-phase-2.gif" width="110" border="0" />
</center>
<br>
<center>
<font color="red"><b>New! MIT 6.978:</b></font>
<a href="6.978/">
<b><font color="blue">Biologically
Motivated Programming Technology for Robust
Systems </font></b>
</a><BR> (Fall 2002)
</center>
</td>
<!---Main Table: right column --->
<td>
<p>
This is the
<b><font color="royalblue">Amorphous Computing HomePage</font></b>.
</p>
<p>
A colony of cells cooperates to form a multicellular organism under
the direction of a genetic program shared by the members of the
colony. A swarm of bees cooperates to construct a hive. Humans group
together to build towns, cities, and nations. These examples raise
fundamental questions for the organization of computing systems:
</p>
<p>
<ul>
<li>
How do we obtain coherent behavior from the cooperation of large
numbers of unreliable parts that are interconnected in unknown,
irregular, and time-varying ways?
<li>
What are the methods for instructing myriads of programmable entities
to cooperate to achieve particular goals?
</ul>
</p>
<p>
These questions have been recognized as fundamental for
generations. Now is an opportune time to tackle the <font
color="royalblue">engineering of emergent order</font>: to
identify the engineering principles and languages that can be
used to observe, control, organize, and exploit the behavior
of programmable multitudes.
</p>
<p>
We call this effort the study of
<em><font color="royalblue">amorphous computing</font></em>.
</p>
<p>
The objective of this research is to create the system-architectural,
algorithmic, and technological foundations for exploiting programmable
materials. These are materials that incorporate vast numbers of
programmable elements that react to each other and to their
environment. Such materials can be fabricated economically, provided
that the computing elements are amassed in bulk without arranging for
precision interconnect and testing. In order to exploit programmable
materials we must identify engineering principles for organizing and
instructing myriad programmable entities to cooperate to achieve
pre-established goals, even though the individual entities are
unreliable and interconnected in unknown, irregular, and time-varying
ways.
</p>
</td>
</tr>
</table>
<!---Main Table:end------------->
<br />
<br />
<hr />
<a name="news" />
<h2><img align="middle" width="100" src="Images/amorph.gif" hspace="20" />Us in the NEWS</h2>
<ul>
<li>
<a href="http://www.computer.org/cise/articles/inspired.htm">Biologically Inspired Computing</a>,
<em>Computing in Science and Engineering</em>, November 2000.
</li>
<li>
<a href="http://www.techreview.com/articles/may00/garfinkel.htm">Biological Computing</a>,
Technology Review, May/June 2000.
</li>
<li>
<a href="cacm-2000.html">Amorphous Computing</a>,
Communications of the ACM, May 2000.
</li>
<li>
<a href="News/nytimes-july16.html">Tiniest Circuits Hold Prospect of Explosive Computer Speeds</a>,
New York Times, July 16, 1999.
</li>
<li>
<a href="News/nytimes-july19.html">Chip Designers Search for Life after Silicon</a>,
New York Times, July 16, 1999.
</li>
<li>
<a href="News/nforbes-sept.html">Computer Science and the Evolution of Genetic Information</a>,
<em>Computing in Science and Engineering</em>, Sept-Oct 1999.
</li>
<li>
<a href="News/boston-globe-1998.pdf">Crossing Computers, Cells</a>,
Boston Globe, 1998.
</li>
<li>
<a href="workshop-sept-99/">DARPA/MIT Amorphous Computing Workshop</a>
</li>
</ul>
<hr />
<a name="research" />
<h2><img align="middle" width="100" src="Images/amorph.gif" hspace="20" />Research and Demos</h2>
Overviews of the research can be found in the article
<a href="cacm-2000.html">Amorphous Computing</a> (Communications of the ACM, May 2000),
our
<a href="http://www.ai.mit.edu/research/abstracts/abstracts2001/bio-machines/bio-machines.shtml">AI Lab Abstracts</a> (2001),
and the
<a href="tucson-talk/">DARPA Presentation on Amorphous Computing slides</a> (April 1998).
The following pages discuss the different projects in more detail and
provide demos for several of the projects.
<p>
<b>Programming Paradigms</b>
</p>
<ul>
<li>
<a href="http://people.csail.mit.edu/jrb/stp/stpg.htm">Space Time Programming</a>
</li>
<li>
<a href="Robust/">Robust Engineering, using biologically-inspired models of cell differentiation and morphogenesis</a> (NSF Project).
<ul>
<li><a href="Robust/laurenc/amorphous/">Self-Repairing Amorphous Topology</a></li>
<li><a href="Robust/joshuag/">Robust Methods for Distributed Synchronization</a></li>
<li><a href="Robust/catie/">Self-assembling 2D Shapes</a></li>
</ul>
</li>
<li>
<a href="Progmat/">Programmable Self-Assembly, Using Biologically-Inspired Local Interactions</a>
</li>
<li>
<a href="/~zucker/paper/">Self-Healing Structures in Amorphous Computing</a>
</li>
<li>
<a href="Progmat/thesis/activecells.html">Towards a Programmable Material</a>
</li>
</ul>
<p>
<b>Infrastructure for an Amorphous Environment</b>
</p>
<ul>
<li>
<a href="Bootstrap/">A Robust Algorithm for Bootstrapping Communication</a>
</li>
<li>
<a href="HC11/">Gunk on the Wall (The first hardware prototype)</a>
</li>
<li>
<a href="Network/">Self Organizing Communication Networks</a>
</li>
<li>
<a href="Coordinates/">Self Organizing Coordinate Systems</a>
</li>
<li>
<a href="curvature-talk/Curvature/">Finding Curvature in an Amorphous Computer</a>
</li>
</ul>
<p>
<b>Synthetic Biology</b>
</p>
<ul>
<li>
<a href="http://www.ai.mit.edu/people/tk/ce/microbial-engineering.html">Microbial Engineering</a>
</li>
<li>
<a href="/~rweiss/bio-programming/">Programming Biological Cells using Engineered Genetic Regulatory Networks</a>
</li>
<li>
Slide shows:
<a href="/~rweiss/bio-programming/dimacs99-evocomp-talk/">Towards <em>in vivo</em> digital circuits</a>,
<a href="inverter-talk/inverter-talk/">Modeling the Chemical Reactions Involved in Biological Inverters</a>
</li>
</ul>
<p>
<b>Models of Physics, Biology</b>
</p>
<ul>
<li>
<a href="/~rauch/phys2.html">Discrete, Amorphous Models of Physics</a> - <a href="/~rauch/dapm">Paper</a>,
<a href="/~rauch/phys2.html">Demos</a>
</li>
<li>
<a href="Tube/">Simulation of Tube Formation (movies)</a>
</li>
<li>
<a href="GrayScott/">Simulation of Reaction Diffusion (Demos)</a>
</li>
</ul>
<p>
<b><a href="related_sites.html">Related Sites</a></b>
</p>
<br />
<br />
<hr />
<a name="hlsim" />
<h2><img align="middle" width="100" src="Images/amorph.gif" hspace="20" />HLSIM - the High Level Simulator</h2>
<p>
HLSIM is a simulator for an ensemble of `gunk' processors which allows
programs to be written in (nearly) Scheme. The gunk processor is
distinguished by having no input or output other than a short-range
radio-like communications device, and possibly some local physical
sensors and actuators. The need for HLSIM arises out of the desire to
simulate thousands of identically-programmed processors running in
parallel at a fine grained level of interleaving, without having to
worry about the details of the interleaving.
</p>
<ul>
<li>
Documentation (<a href="hlsim/doc/hlsim.html">html</a>, <a href="hlsim.ps">postscript</a>)
</li>
<li>
<a href="6.966/hlsim/">How to Install</a>
</li>
<!--
<li>
<a href="/~hal/hpm-example/">Example: HPM algorithm</a>
</li>
-->
<li>
<a href="6.966/dder-examples/">Introductory HLSIM examples by DDeR</a>
</li>
<li>
<a href="6.966/advanced/">Some Modules and Utilities for hlsim</a>
</li>
</ul>
<hr />
<br />
<a href="/projects/mac/"><img src="Images/swiss-3.gif" width="50" alt="back to Project MAC Home" />Back to Project MAC Home Page</a>
</body>
</html>
|
Amorphous Computing Home Page
![](Images/amorphous-title.jpg)
| | |
| --- | --- |
|
* [**In the News**](#news)
* [**Research**](#research)
* [**Demos**](#research)
* [**HLSIM**](#hlsim)
* [**Publications**](paperlisting.html)
* [**People**](/projects/mac/mac-people.html)
* [**Related Sites**](related_sites.html)
**New! MIT 6.978:**
[**Biologically
Motivated Programming Technology for Robust
Systems**](6.978/) (Fall 2002)
|
This is the
**Amorphous Computing HomePage**.
A colony of cells cooperates to form a multicellular organism under
the direction of a genetic program shared by the members of the
colony. A swarm of bees cooperates to construct a hive. Humans group
together to build towns, cities, and nations. These examples raise
fundamental questions for the organization of computing systems:
* How do we obtain coherent behavior from the cooperation of large
numbers of unreliable parts that are interconnected in unknown,
irregular, and time-varying ways?
* What are the methods for instructing myriads of programmable entities
to cooperate to achieve particular goals?
These questions have been recognized as fundamental for
generations. Now is an opportune time to tackle the engineering of emergent order: to
identify the engineering principles and languages that can be
used to observe, control, organize, and exploit the behavior
of programmable multitudes.
We call this effort the study of
*amorphous computing*.
The objective of this research is to create the system-architectural,
algorithmic, and technological foundations for exploiting programmable
materials. These are materials that incorporate vast numbers of
programmable elements that react to each other and to their
environment. Such materials can be fabricated economically, provided
that the computing elements are amassed in bulk without arranging for
precision interconnect and testing. In order to exploit programmable
materials we must identify engineering principles for organizing and
instructing myriad programmable entities to cooperate to achieve
pre-established goals, even though the individual entities are
unreliable and interconnected in unknown, irregular, and time-varying
ways.
|
| http://groups.csail.mit.edu/mac/projects/amorphous/ |
<html>
<head>
<base="http://www.lysator.liu.se/pinball/expo/">
<title>Pinball Expo 1994 Web Site</title>
</head>
<body>
<h1><IMG ALT="Pinball Expo 1994" ALIGN=middle SRC=expopic.gif> Welcome to Pinball Expo 1994</h1>
<p><hr>
<a href="flr01.jpg"><IMG SRC=flr01-t.gif></a><b>Expo 1994 is open!</b><p>
<hr>
This is the semi-official Web site for the Expo, with information and exhibits direct from the floor.<p>
<hr>
<ul>
<h2><IMG ALIGN=middle SRC=infoicon.gif> <a href="brochure.html">Read the Expo Flyer</a></h2>
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<h2><IMG ALIGN=middle SRC=pinhead.gif> <a href="floor.html">Visit the Exhibit Hall</a></h2>
<h2><IMG ALIGN=middle SRC=infoicon.gif> <a href="archives.html">Other Pinball Web Sites</a></h2>
</ul>
<p>
<hr>
<a href="about.html">Credits and Acknowledgements</a><p>
<a href="mailto:koziarz@mcs.com">Comments to Webmaster</a>
</body>
</html>
|
Pinball Expo 1994 Web Site
# Pinball Expo 1994 Welcome to Pinball Expo 1994
---
[![](flr01-t.gif)](flr01.jpg)**Expo 1994 is open!**
---
This is the semi-official Web site for the Expo, with information and exhibits direct from the floor.
---
## [Read the Expo Flyer](brochure.html)
## [Schedule of Events](schedule.html)
## [Registration Information](register.html)
## [Directions and Accomodations](chicago.html)
## [Visit the Exhibit Hall](floor.html)
## [Other Pinball Web Sites](archives.html)
---
[Credits and Acknowledgements](about.html)
[Comments to Webmaster](mailto:koziarz@mcs.com)
| http://www.lysator.liu.se/pinball/expo/ |
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<h1>Clonezilla</h1>
The Free and Open Source Software for Disk <a href="https://en.wikipedia.org/wiki/Disk_imaging" target=_blank>Imaging</a> and <a href="https://en.wikipedia.org/wiki/Disk_cloning" target=_blank>Cloning</a>
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<h3><font color="#3333ff">What is Clonezilla?</font></h3>
Clonezilla is a partition and disk imaging/cloning program similar to <a href="http://en.wikipedia.org/wiki/Acronis_True_Image" target=_blank>True Image®</a> or <a target="_blank" href="http://en.wikipedia.org/wiki/Ghost_%28software%29">Norton Ghost®</a>. It helps you to do system deployment, bare metal backup and recovery. Three types of Clonezilla are available, <a href="clonezilla-live.php">Clonezilla live</a>, <a href="show-live-doc-content.php?topic=clonezilla-live/doc/11_lite_server" >Clonezilla lite server</a>, and <a href="./clonezilla-SE/">Clonezilla SE (server edition)</a>. Clonezilla live is suitable for single machine backup and restore. While Clonezilla lite server or SE is for massive deployment, it can clone many (40 plus!) computers simultaneously. Clonezilla saves and restores only used blocks in the hard disk. This increases the clone efficiency. With some high-end hardware in a 42-node cluster, a multicast restoring at rate 8 GB/min was reported.<br>
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<h3><font color="#3333ff">Features:</font></h3>
<ul>
<li>Many File systems are supported: (1) ext2, ext3, ext4, reiserfs, reiser4, xfs, jfs, btrfs, f2fs and nilfs2 of GNU/Linux, (2) FAT12, FAT16, FAT32, exFAT and NTFS of MS Windows, (3) HFS+ and APFS of Mac OS, (4) UFS of FreeBSD, NetBSD, and OpenBSD, (5) minix of Minix, and (6) VMFS3 and VMFS5 of VMWare ESX. Therefore you can clone GNU/Linux, MS windows, Intel-based Mac OS, FreeBSD, NetBSD, OpenBSD, Minix, VMWare ESX and Chrome OS/Chromium OS, no matter it's 32-bit (x86) or 64-bit (x86-64) OS. For these file systems, only used blocks in partition are saved and restored by <a href="http://partclone.org" target=_blank>Partclone</a>. For unsupported file system, sector-to-sector copy is done by <a href="https://en.wikipedia.org/wiki/Dd_(Unix)" target=_blank>dd</a> in Clonezilla.
<li><font color=red>LVM2</font> (LVM version 1 is not) under GNU/Linux is supported.
<li><font color=red>LUKS</font> (Linux Unified Key Setup) is supported.
<li>Boot loader, including grub (version 1 and <font color=red>version 2</font>) and syslinux, could be reinstalled.
<li>Both <a href="http://en.wikipedia.org/wiki/Master_boot_record" target=_blank>MBR</a> and <a href="http://en.wikipedia.org/wiki/GUID_Partition_Table" target=_blank>GPT</a> partition formats of hard drive are supported. Clonezilla live also can be booted on a <a href="http://en.wikipedia.org/wiki/BIOS" target=_blank>BIOS</a> or <a href="http://en.wikipedia.org/wiki/Unified_Extensible_Firmware_Interface" target=_blank>uEFI</a> machine.
<li>Unattended mode is supported. Almost all steps can be done via commands and options. You can also use <a href="fine-print-live-doc.php?path=clonezilla-live/doc/99_Misc/00_live-boot-parameters.doc">a lot of boot parameters</a> to customize your own imaging and cloning.
<li>One image restoring to multiple local devices is supported.
<li>Image could be encrypted. This is done with <a href="http://ecryptfs.org/" target=_blank>ecryptfs</a>, a POSIX-compliant enterprise cryptographic stacked filesystem.
<li><font color=red>Multicast</font> is supported in Clonezilla SE, which is suitable for massive clone. You can also remotely use it to save or restore a bunch of computers if PXE and Wake-on-LAN are supported in your clients.
<li><font color=red>Bittorrent (BT)</font> is supported in Clonezilla lite server, which is suitable for massive deployment. The job for BT mode is done by <a href="https://github.com/tjjh89017/ezio" target=_blank>Ezio</a>.
<li>The image file can be on local disk, ssh server, samba server, NFS server or <a href="http://en.wikipedia.org/wiki/WebDAV" target=_blank>WebDAV</a> server.
<li>AES-256 encryption could be used to secures data access, storage and transfer.
<li>Based on <a href="http://partclone.org" target=_blank>Partclone</a> (default), <a href="http://www.partimage.org" target=_blank> Partimage</a> (optional), <a href="http://jp-andre.pagesperso-orange.fr/advanced-ntfs-3g.html" target=_blank>ntfsclone</a> (optional), or dd to image or clone a partition. However, Clonezilla, containing some other programs, can save and restore not only partitions, but also a whole disk.
<li>By using another free software <a href="http://drbl-winroll.sourceforge.net/">drbl-winroll</a>, which is also developed by us, the hostname, group, and SID of cloned MS windows machine can be automatically changed.
</ul>
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<h3><font color="#3333ff">Minimum System Requirements for Clonezilla live:</font></h3>
<ul>
<li>X86 or x86-64 processor
<li>196 MB of system memory (RAM)
<li>Boot device, e.g. CD/DVD Drive, USB port, PXE, or hard drive
</ul>
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<h3><font color="#3333ff">Limitations:</font></h3>
<ul>
<li>The destination partition must be equal or larger than the source one.
<li>Differential/incremental backup is not implemented yet.
<li>Online imaging/cloning is not implemented yet. The partition to be imaged or cloned has to be unmounted.
<li>Due to the image format limitation, the image can not be explored or mounted. You can _NOT_ recovery single file from the image. However, you still have workaround to make it, read <a href="http://drbl.org/faq/fine-print.php?path=./2_System/43_read_ntfsimg_content.faq#43_read_ntfsimg_content.faq" target=_blank>this</a>.
<li>Recovery Clonezilla live with multiple CDs or DVDs is not implemented yet. Now all the files have to be in one CD or DVD if you choose to create the recovery iso file.
</ul>
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<h3><font color="#3333ff">License:</font></h3>
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<h3><font color="#3333ff">Which Clonezilla Shall I Use ?</font></h3>
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<li><a href="clonezilla-live.php">Clonezilla Live</a>: Clonezilla live allows you to use CD/DVD or USB flash drive to boot and run clonezilla (Unicast only)</li>
<li><a href="show-live-doc-content.php?topic=clonezilla-live/doc/11_lite_server">Clonezilla lite server</a>: Clonezilla lite server allows you to use Clonezilla live to do massively cloning (unicast, broadcast, multicast, bittorrent are supported)
<li><a href="./clonezilla-SE/">Clonezilla SE</a>: Clonezilla SE is included in DRBL, therefore a DRBL server must first be set up in order to use Clonezilla to do massively cloning (unicast, broadcast and multicast are supported)
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Clonezilla - About
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[home](././) |
Clonezilla
The Free and Open Source Software for Disk [Imaging](https://en.wikipedia.org/wiki/Disk_imaging) and [Cloning](https://en.wikipedia.org/wiki/Disk_cloning) |
[About](././)
[News](https://sourceforge.net/p/clonezilla/news/)
[Screenshots](./screenshots/)
[Live CD/USB](./clonezilla-live.php)
[Live Docs](./clonezilla-usage/clonezilla-live-usage.php)
[Server Edition](./clonezilla-SE/)
[Download](./downloads.php)
[CD/USB key vendors](./cd-usb-key-vendors/)
[DRBL-winroll](http://www.drbl-winroll.org)
[Related LiveCD](./related-live-cd/)
[Testimonials](./testimonials/)
[Lecture Materials](./lecture-materials/)
[Related Articles](./related-articles/)
[Partners](./partners/)
[FAQ/Q&A](http://drbl.org/faq/)
[Forum](https://sourceforge.net/p/clonezilla/discussion/)
[Mailing Lists](https://sourceforge.net/p/clonezilla/mailman/)
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[Step-by-step docs](.//clonezilla-live-doc.php)
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### What is Clonezilla?
Clonezilla is a partition and disk imaging/cloning program similar to [True Image®](http://en.wikipedia.org/wiki/Acronis_True_Image) or [Norton Ghost®](http://en.wikipedia.org/wiki/Ghost_%28software%29). It helps you to do system deployment, bare metal backup and recovery. Three types of Clonezilla are available, [Clonezilla live](clonezilla-live.php), [Clonezilla lite server](show-live-doc-content.php?topic=clonezilla-live/doc/11_lite_server), and [Clonezilla SE (server edition)](./clonezilla-SE/). Clonezilla live is suitable for single machine backup and restore. While Clonezilla lite server or SE is for massive deployment, it can clone many (40 plus!) computers simultaneously. Clonezilla saves and restores only used blocks in the hard disk. This increases the clone efficiency. With some high-end hardware in a 42-node cluster, a multicast restoring at rate 8 GB/min was reported.
### Features:
* Many File systems are supported: (1) ext2, ext3, ext4, reiserfs, reiser4, xfs, jfs, btrfs, f2fs and nilfs2 of GNU/Linux, (2) FAT12, FAT16, FAT32, exFAT and NTFS of MS Windows, (3) HFS+ and APFS of Mac OS, (4) UFS of FreeBSD, NetBSD, and OpenBSD, (5) minix of Minix, and (6) VMFS3 and VMFS5 of VMWare ESX. Therefore you can clone GNU/Linux, MS windows, Intel-based Mac OS, FreeBSD, NetBSD, OpenBSD, Minix, VMWare ESX and Chrome OS/Chromium OS, no matter it's 32-bit (x86) or 64-bit (x86-64) OS. For these file systems, only used blocks in partition are saved and restored by [Partclone](http://partclone.org). For unsupported file system, sector-to-sector copy is done by [dd](https://en.wikipedia.org/wiki/Dd_(Unix)) in Clonezilla.
* LVM2 (LVM version 1 is not) under GNU/Linux is supported.
* LUKS (Linux Unified Key Setup) is supported.
* Boot loader, including grub (version 1 and version 2) and syslinux, could be reinstalled.
* Both [MBR](http://en.wikipedia.org/wiki/Master_boot_record) and [GPT](http://en.wikipedia.org/wiki/GUID_Partition_Table) partition formats of hard drive are supported. Clonezilla live also can be booted on a [BIOS](http://en.wikipedia.org/wiki/BIOS) or [uEFI](http://en.wikipedia.org/wiki/Unified_Extensible_Firmware_Interface) machine.
* Unattended mode is supported. Almost all steps can be done via commands and options. You can also use [a lot of boot parameters](fine-print-live-doc.php?path=clonezilla-live/doc/99_Misc/00_live-boot-parameters.doc) to customize your own imaging and cloning.
* One image restoring to multiple local devices is supported.
* Image could be encrypted. This is done with [ecryptfs](http://ecryptfs.org/), a POSIX-compliant enterprise cryptographic stacked filesystem.
* Multicast is supported in Clonezilla SE, which is suitable for massive clone. You can also remotely use it to save or restore a bunch of computers if PXE and Wake-on-LAN are supported in your clients.
* Bittorrent (BT) is supported in Clonezilla lite server, which is suitable for massive deployment. The job for BT mode is done by [Ezio](https://github.com/tjjh89017/ezio).
* The image file can be on local disk, ssh server, samba server, NFS server or [WebDAV](http://en.wikipedia.org/wiki/WebDAV) server.
* AES-256 encryption could be used to secures data access, storage and transfer.
* Based on [Partclone](http://partclone.org) (default), [Partimage](http://www.partimage.org) (optional), [ntfsclone](http://jp-andre.pagesperso-orange.fr/advanced-ntfs-3g.html) (optional), or dd to image or clone a partition. However, Clonezilla, containing some other programs, can save and restore not only partitions, but also a whole disk.
* By using another free software [drbl-winroll](http://drbl-winroll.sourceforge.net/), which is also developed by us, the hostname, group, and SID of cloned MS windows machine can be automatically changed.
### Minimum System Requirements for Clonezilla live:
* X86 or x86-64 processor
* 196 MB of system memory (RAM)
* Boot device, e.g. CD/DVD Drive, USB port, PXE, or hard drive
### Limitations:
* The destination partition must be equal or larger than the source one.
* Differential/incremental backup is not implemented yet.
* Online imaging/cloning is not implemented yet. The partition to be imaged or cloned has to be unmounted.
* Due to the image format limitation, the image can not be explored or mounted. You can \_NOT\_ recovery single file from the image. However, you still have workaround to make it, read [this](http://drbl.org/faq/fine-print.php?path=./2_System/43_read_ntfsimg_content.faq#43_read_ntfsimg_content.faq).
* Recovery Clonezilla live with multiple CDs or DVDs is not implemented yet. Now all the files have to be in one CD or DVD if you choose to create the recovery iso file.
### License:
* Clonezilla itself is licensed under the GNU General Public License (GPL) Version 2. However, to run Clonezilla, a lot of free and open source software, e.g. the Linux kernel and a minimal GNU/Linux OS, are required.
### Which Clonezilla Shall I Use ?
* [Clonezilla Live](clonezilla-live.php): Clonezilla live allows you to use CD/DVD or USB flash drive to boot and run clonezilla (Unicast only)
* [Clonezilla lite server](show-live-doc-content.php?topic=clonezilla-live/doc/11_lite_server): Clonezilla lite server allows you to use Clonezilla live to do massively cloning (unicast, broadcast, multicast, bittorrent are supported)
* [Clonezilla SE](./clonezilla-SE/): Clonezilla SE is included in DRBL, therefore a DRBL server must first be set up in order to use Clonezilla to do massively cloning (unicast, broadcast and multicast are supported)
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| https://clonezilla.org/ |
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<meta name="description" content="Tacky treasures, as defined by Julie Mangin, are those that are not only tacky, but that possess an additional quality such as naivete, irony, or other qualities that test the boundaries or good and bad taste.">
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<td colspan="8" bgcolor="#FFFFFF"><h1 class="homepage"><img src="images/nav/jtt-title.gif" alt="Julie's Tacky Treasures" width="765" height="65"></h1><div id="pagecontent">
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<h3>Random Tackiness <br>
</h3>
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document.write("" + "" + hyperlinks[index] + "");
<!--document.write("</DL>\n");-->
</script>
</div>
<p><span class="largecap">W</span>hat makes something a tacky treasure?
A tacky treasure is, first of all, tacky. However, to be a treasure, it
must possess an additional quality, which could be any one of these: a
naïve yet ultimately flawed effort to be sophisticated or stylish;
a complete lack of shame in exploiting poor taste; or a deliberate flaunting
of poor taste as a rebellion against established norms. </p>
<p>You can <a href="about.html">read more of my thoughts on tacky treasures</a>,
or you can browse the treasures now, and come to your own understanding
of the concept. </p>
<p><strong>NEW!</strong> <a href="topics/ttrs2023.html">Tacky Treasures Road Show, 2023</a></p>
<ul>
<li><a href="top/">Top Tacky Treasures</a>: The Mark Eden Bust Developer,
the Popener, Jesus Playing Football, and other delightfully tasteless
objects</li>
<li><a href="topics/">Tacky Topics</a>: The Tacky Treasures Road Show,
Mike the Headless Chicken, big heads, art cars, salt & pepper
shakers, <a href="jigsaw/index.html">digital jigsaw puzzles</a>, and more.</li>
<li><a href="places/">Tacky Places</a>: Foamhenge, Cooter's Place, Planet
Wayside, and other whimsical places</li>
<li><a href="seasonal/">Seasonal Tacky</a>: The holidays seem to bring
the tacky out of some people</li>
</ul>
<p> </p>
</div>
<div class="space"></div>
<div class="clear"></div>
<div class="pink"></div>
<div class="dkpink"></div></td>
</tr>
<tr valign="top">
<td colspan="7" align="center" bgcolor="#FFFFFF"><span class="sitenav">Copyright
© 2000-2023, Julie Mangin. All Rights Reserved. </span></td>
<td bgcolor="#FFFFFF"><span class="sitenav">
<!-- #BeginDate format:Am1 -->June 14, 2023<!-- #EndDate -->
</span></td>
</tr>
</table>
<p> </p></body>
</html>
|
Julie's Tacky Treasures
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| | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- |
| [HOME](http://www.tackytreasures.com) | | | [TREASURES](top/) | [TOPICS](topics/) | [PLACES](places/) | [SEASONAL](seasonal/) | [CONTACT](julie.php) |
| Julie's Tacky Treasures
Random Tackiness
images = new Array(10);
images[0] = "<a class='caption' href='top/markeden.html'><img src='images/edenhands-random.jpg' alt='Mark Eden Bust Developer' align='center'border='2' height='150' width='150'></a>";
images[1] = "<a class='caption' href='top/lungashtray.html'><img src='images/lungashtray-random.jpg' alt='Ashtray in the shape of a human lung' align='center'border='2' height='150' width='150'></a>";
images[2] = "<a class='caption' href='top/multifunction.html'><img src='images/multifunctionlamp-random.jpg' alt='Telephone Lamp with cigarette lighter and clock' align='center'border='2' height='150' width='150'></a>";
images[3] = "<a class='caption' href='top/snakebite.html'><img src='images/snakebitekit-random.jpg' alt='Moonshine jug with ballerina' align='center'border='2' height='150' width='150'></a>";
images[4] = "<a class='caption' href='top/eatshit.html'><img src='images/eatshit-random.jpg' alt='Ronald McDonald button' align='center'border='2' height='150' width='150'></a>";
images[5] = "<a class='caption' href='top/popener.html'><img src='images/popener-random.jpg' alt='The Popener' align='center'border='2' height='150' width='150'></a>";
images[6] = "<a class='caption' href='top/tiki.html'><img src='images/tiki-random.jpg' alt='Tiki Tissue Dispenser' align='center'border='2' height='150' width='150'></a>";
images[7] = "<a class='caption' href='top/rubberbandvest.html'><img src='images/rubberbandvest-random.jpg' alt='The Rubber Band Vest' align='center'border='2' height='150' width='150'></a>";
images[8] = "<a class='caption' href='top/jesusplayingfootball.html'><img src='images/jesusplayingfootball-random.jpg' alt='Jesus playing football' align='center'border='2' height='150' width='150'></a>";
images[9] = "<a class='caption' href='top/deerlamp.html'><img src='images/deerlamp-random.jpg' alt='Three-legged deer lamp' align='center'border='2' height='150' width='150'></a>";
index = Math.floor(Math.random() \* images.length);
document.write("" + "" + images[index] + "");
hyperlinks = new Array(10);
hyperlinks[0] = "<p class='caption'><a class='caption' href='top/markeden.html'>Mark Eden Bust Developer</a></p>";
hyperlinks[1] = "<p class='caption'><a class='caption' href='top/lungashtray.html'>Lung Ashtray</a></p>";
hyperlinks[2] = "<p class='caption'><a class='caption' href='top/multifunction.html'>Multi-function Lamp</a></p>";
hyperlinks[3] = "<p class='caption'><a class='caption' href='top/snakebite.html'>Snake Bite Kit</a></p>";
hyperlinks[4] = "<p class='caption'><a class='caption' href='top/eatshit.html'>Eat Shit Button</a></p>";
hyperlinks[5] = "<p class='caption'><a class='caption' href='top/popener.html'>The Popener</a></p>";
hyperlinks[6] = "<p class='caption'><a class='caption' href='top/tiki.html'>Tiki Tissue Dispenser</a></p>";
hyperlinks[7] = "<p class='caption'><a class='caption' href='top/rubberbandvest.html'>Rubber Band Vest</a></p>";
hyperlinks[8] = "<p class='caption'><a class='caption' href='top/jesusplayingfootball.html'>Jesus Playing Football</a></p>";
hyperlinks[9] = "<p class='caption'><a class='caption' href='top/deerlamp.html'>Three-legged Deer Lamp</a></p>";
<!--document.write("<DL>\n");-->
document.write("" + "" + hyperlinks[index] + "");
<!--document.write("</DL>\n");-->
What makes something a tacky treasure?
A tacky treasure is, first of all, tacky. However, to be a treasure, it
must possess an additional quality, which could be any one of these: a
naïve yet ultimately flawed effort to be sophisticated or stylish;
a complete lack of shame in exploiting poor taste; or a deliberate flaunting
of poor taste as a rebellion against established norms.
You can [read more of my thoughts on tacky treasures](about.html),
or you can browse the treasures now, and come to your own understanding
of the concept.
**NEW!** [Tacky Treasures Road Show, 2023](topics/ttrs2023.html)
* [Top Tacky Treasures](top/): The Mark Eden Bust Developer,
the Popener, Jesus Playing Football, and other delightfully tasteless
objects
* [Tacky Topics](topics/): The Tacky Treasures Road Show,
Mike the Headless Chicken, big heads, art cars, salt & pepper
shakers, [digital jigsaw puzzles](jigsaw/index.html), and more.
* [Tacky Places](places/): Foamhenge, Cooter's Place, Planet
Wayside, and other whimsical places
* [Seasonal Tacky](seasonal/): The holidays seem to bring
the tacky out of some people
|
| Copyright
© 2000-2023, Julie Mangin. All Rights Reserved. |
June 14, 2023
|
| http://tackytreasures.com/ |
<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN">
<html>
<head>
<TITLE>Calorie Burn Calculator</title>
</head>
<BODY bgcolor="#a9a9a9" leftmargin="0" topmargin="0" marginheight="0">
<SCRIPT type="text/JavaScript">
<!--//--><h3>Your browser does not support JavaScript.</h3>
<!--//--><p>The calorie calculator will not work with your browser</p><hr>
<!--//start hiding script from old browsers
function msg(text) {
//this displays a message in the status bar
window.defaultStatus='';
window.status=text;
}
function Num(str) {
//check for valid numbers
for (var i=0; i<str.length; i++)
{var ch = str.substring(i, i + 1)
if (ch!="." && (ch < "0" || ch > "9"))
{alert("Please enter a valid number");
return false;}}
return true;
}
function calc(form) {
//get weight in either lbs or kg
var weight = form.wt.value
//get pace for either miles or km
var pace = (form.pmin.value * 60);
//get duration and convert duration to hours, from hours, and minutes
var dur = ((form.hrs.value * 1) + (form.min.value / 60));
//get elevation gain during hike
var elv = form.elev.value;
//check for necessary values
if(form.wt.value * 1 == 0)
{alert("Please enter your Weight");
return false;}
if(pace == 0)
{alert("Please enter your Pace");
return false;}
if(dur == 0)
{alert("Please enter Duration");
return false;}
if(elv == 0)
{alert("Please enter Elevation");
return false;}
//insert zeros in blank fields
if(form.pmin.value == "") form.pmin.value = 0;
if(form.hrs.value == "") form.hrs.value = 0;
if(form.min.value == "") form.min.value = 0;
if(form.elev.value == "") form.elev.value = 0;
//eliminate decimal places in time values
hrs2 = form.hrs.value;
form.hrs.value = Math.floor(hrs2);
form.min.value = (form.min.value * 1) + (hrs2 - Math.floor(hrs2)) * 60;
min2 = form.min.value;
form.min.value = Math.floor(min2);
pmin2 = form.pmin.value;
form.pmin.value = Math.floor(pmin2);
//correct for minutes >= 60
if(form.min.value >= 60)
{min1 = form.min.value / 60;
form.min.value = Math.round(60 * (min1 - Math.floor(min1)));
form.hrs.value = form.hrs.value * 1 + Math.floor(min1);}
//calculate calories burned!
dist = ((dur/(form.pmin.value/60)));
form.dist.value = parseInt(dist);
diff=(((((elv/(dist*5280)*100)*4)+(Math.sqrt((dist*dist)*6))))/2.5);
form.hikediff.value = Math.round(diff);
cal = ((((weight * 2462.4)+44044)/Math.pow(pace,1.0045))+(Math.sqrt((Math.pow(diff,3)))));
form.calhr.value = parseInt(cal);
form.caltot.value = parseInt(cal * dur);
//extra stuff
if (form.min.value < 10)
{form.min.value = 0+form.min.value}
}
function clear(form) {
//clear all values
form.wt.value = ""; form.pmin.value = "";
form.min.value = "";form.hrs.value = "";
form.caltot.value = "";form.calhr.value = "";
form.elv.value = "";form.elev.value = "";
}
//done hiding from old browsers --></SCRIPT>
<table align="center"><tr><td valign="top">
<CENTER>
<font face="Verdana" size="4">
<b>CALORIE BURN CALCULATOR</b></font>
<br>
<FORM>
<font face="Verdana" size="1" color="#dc143c">
<b>THIS CALCULATOR IS FOR ENTERTAINMENT PURPOSES AND<br>HAS NO SCIENTIFIC SUPPORT AND DOES NOT CLAIM TO BE ACCURATE.</b>
<font color="#00008b">
<br>However, I have spent a considerable amount of time<br>trying to make the results close to other charts on the internet.
</font></font>
<BR><br>
<table border=0 cellpadding=0 width="600" align="center">
<tr>
<td>
<TABLE border=1 cellPadding=0 cellspacing=0 width="150" bgcolor="#f5deb3">
<tr><td>
<table align="center" border=0 cellpadding=2 width="150">
<TR><TD align="center">
<font face="Verdana" size="2"><b>Weight</b></font>
</TD></tr>
<TR><TD align="center">
<font face="Verdana" size="1"><b>
<INPUT class="inputtext" onchange=(Num(this.value)) size=7 name=wt>Lbs</b></font>
</TD></tr>
</table>
</td></tr>
</table>
</td>
<td>
<TABLE border=1 cellPadding=0 cellspacing=0 width="150" bgcolor="#f5deb3">
<tr><td>
<table align="center" border=0 cellpadding=2 width="150">
<TR><TD align="center">
<font face="Verdana" size="2"><b>Pace</b></font>
</TD></tr>
<TR><TD align="center">
<font face="Verdana" size="1"><b>
<INPUT class="inputtext" onchange=(Num(this.value)) size=3 name=pmin> min/mile</b></font>
</TD></tr>
</table>
</td></tr>
</table>
</td>
<td>
<TABLE border=1 cellPadding=0 cellspacing=0 width="150" bgcolor="#f5deb3">
<tr><td>
<table align="center" border=0 cellpadding=2 width="150">
<tr><TD align="center" colspan="2">
<font face="Verdana" size="2"><b>Duration</b></font>
</TD></TR>
<TR><TD align="center">
<font face="Verdana" size="1"><b>
<INPUT class="inputtext" name=hrs onchange=(Num(this.value)) size=3> hrs</b></font>
</TD>
<TD align="center">
<font face="Verdana" size="1"><b>
<INPUT class="inputtext" name=min onchange=(Num(this.value)) size=3> min</b></font>
</TD></TR>
</table>
</td></tr>
</table>
</td>
<td>
<TABLE border=1 cellPadding=0 cellspacing=0 width="150" bgcolor="#f5deb3">
<tr><td>
<table align="center" border=0 cellpadding=2 width="150">
<tr><TD align="center">
<font face="Verdana" size="2"><b>Elevation Gain</b></font>
</TD></TR>
<TR><TD align="center">
<font face="Verdana" size="1"><b>
<INPUT class="inputtext" name=elev onchange=(Num(this.value)) size=7> feet</b></font>
</TD></TR>
</table>
</td></tr>
</table>
</td></tr>
</table>
<table border=0 cellpadding=10 width="500" align="center">
<tr><td align="center">
<INPUT class="menutext" onclick=calc(this.form) type=button value="Calculate !">
</td><td align="center">
<INPUT class="menutext" onclick=clear(this.form) type=reset value="Reset Form">
</td><td align="center">
<INPUT type="button" VALUE="Return" onClick="Javascript:history.back()">
</TD></tr>
</table>
<font face="Verdana" size="2" color="#800000"><b>
One pound of fat is roughly equivalent to 3,500 calories
</b></font>
<TABLE align="center" border=0 cellPadding=10 cellspacing=0 width="300">
<tr><td>
<TABLE border=1 cellPadding=0 cellspacing=0 width="150" bgcolor="#8fbc8f">
<tr><td>
<table align="center" border=0 cellpadding=2 width="150">
<tr><TD align="center">
<font face="Verdana" size="1"><b>Calories / Hour</b></font>
</TD></TR>
<TR><TD align="center">
<INPUT class="inputtext" size=9 name=calhr>
</TD></TR>
</table>
</td></tr>
</table>
</td>
<td>
<TABLE border=1 cellPadding=0 cellspacing=0 width="150" bgcolor="#8fbc8f">
<tr><td>
<table align="center" border=0 cellpadding=2 width="150">
<tr><TD align="center">
<font face="Verdana" size="1"><b>Total Calories</b></font>
</TD></TR>
<TR><TD align="center">
<INPUT class="inputtext" size=9 name=caltot>
</TD></TR>
</table>
</td></tr>
</table>
</td></tr>
</table>
<TABLE align="center" border=0 cellPadding=10 cellspacing=0 width="300">
<tr><td>
<TABLE border=1 cellPadding=0 cellspacing=0 width="150" bgcolor="#f08080">
<tr><td>
<table align="center" border=0 cellpadding=2 width="150">
<tr><TD align="center">
<font face="Verdana" size="1"><b>Miles Hiked</b></font>
</TD></TR>
<TR><TD align="center">
<INPUT class="inputtext" size=9 name=dist>
</TD></TR>
</table>
</td></tr>
</table>
</td>
<td>
<TABLE border=1 cellPadding=0 cellspacing=0 width="150" bgcolor="#f08080">
<tr><td>
<table align="center" border=0 cellpadding=2 width="150">
<tr><TD align="center">
<font face="Verdana" size="1"><b>Hike Difficulty Level</b></font>
</TD></TR>
<TR><TD align="center">
<INPUT class="inputtext" size=9 name=hikediff>
</TD></TR>
</table>
</td></tr>
</table>
</td></tr>
</table>
<table cellspacing="2" cellpadding="2" border="2">
<tr>
<td bgcolor="#c0c0c0" colspan="2"><font face="Verdana" size="2"><b>
Score Difficulty Level </b></font>
</td>
</tr>
<tr>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
0 - 7
</font></td>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
EASY
</font></td>
</tr>
<tr>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
8 - 13
</font></td>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
MODERATE
</font></td>
</tr>
<tr>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
14 - 18
</font></td>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
CHALLENGING
</font></td>
</tr>
<tr>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
19 - 23
</font></td>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
DIFFICULT
</font></td>
</tr>
<tr>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
24 - 27
</font></td>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
VERY DIFFICULT
</font></td>
</tr>
<tr>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
28 +
</font></td>
<td bgcolor="#4682b4" align="center"><font face="Verdana" size="2" color="#ffff00">
EXTREME
</font></td>
</tr>
</table>
</FORM>
</CENTER>
</td></tr></table>
</BODY></HTML>
|
Calorie Burn Calculator
<!--//--><h3>Your browser does not support JavaScript.</h3>
<!--//--><p>The calorie calculator will not work with your browser</p><hr>
<!--//start hiding script from old browsers
function msg(text) {
//this displays a message in the status bar
window.defaultStatus='';
window.status=text;
}
function Num(str) {
//check for valid numbers
for (var i=0; i<str.length; i++)
{var ch = str.substring(i, i + 1)
if (ch!="." && (ch < "0" || ch > "9"))
{alert("Please enter a valid number");
return false;}}
return true;
}
function calc(form) {
//get weight in either lbs or kg
var weight = form.wt.value
//get pace for either miles or km
var pace = (form.pmin.value \* 60);
//get duration and convert duration to hours, from hours, and minutes
var dur = ((form.hrs.value \* 1) + (form.min.value / 60));
//get elevation gain during hike
var elv = form.elev.value;
//check for necessary values
if(form.wt.value \* 1 == 0)
{alert("Please enter your Weight");
return false;}
if(pace == 0)
{alert("Please enter your Pace");
return false;}
if(dur == 0)
{alert("Please enter Duration");
return false;}
if(elv == 0)
{alert("Please enter Elevation");
return false;}
//insert zeros in blank fields
if(form.pmin.value == "") form.pmin.value = 0;
if(form.hrs.value == "") form.hrs.value = 0;
if(form.min.value == "") form.min.value = 0;
if(form.elev.value == "") form.elev.value = 0;
//eliminate decimal places in time values
hrs2 = form.hrs.value;
form.hrs.value = Math.floor(hrs2);
form.min.value = (form.min.value \* 1) + (hrs2 - Math.floor(hrs2)) \* 60;
min2 = form.min.value;
form.min.value = Math.floor(min2);
pmin2 = form.pmin.value;
form.pmin.value = Math.floor(pmin2);
//correct for minutes >= 60
if(form.min.value >= 60)
{min1 = form.min.value / 60;
form.min.value = Math.round(60 \* (min1 - Math.floor(min1)));
form.hrs.value = form.hrs.value \* 1 + Math.floor(min1);}
//calculate calories burned!
dist = ((dur/(form.pmin.value/60)));
form.dist.value = parseInt(dist);
diff=(((((elv/(dist\*5280)\*100)\*4)+(Math.sqrt((dist\*dist)\*6))))/2.5);
form.hikediff.value = Math.round(diff);
cal = ((((weight \* 2462.4)+44044)/Math.pow(pace,1.0045))+(Math.sqrt((Math.pow(diff,3)))));
form.calhr.value = parseInt(cal);
form.caltot.value = parseInt(cal \* dur);
//extra stuff
if (form.min.value < 10)
{form.min.value = 0+form.min.value}
}
function clear(form) {
//clear all values
form.wt.value = ""; form.pmin.value = "";
form.min.value = "";form.hrs.value = "";
form.caltot.value = "";form.calhr.value = "";
form.elv.value = "";form.elev.value = "";
}
//done hiding from old browsers -->
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
|
**CALORIE BURN CALCULATOR**
**THIS CALCULATOR IS FOR ENTERTAINMENT PURPOSES ANDHAS NO SCIENTIFIC SUPPORT AND DOES NOT CLAIM TO BE ACCURATE.**
However, I have spent a considerable amount of timetrying to make the results close to other charts on the internet.
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**One pound of fat is roughly equivalent to 3,500 calories**
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| http://nwhiker.com/calorieburn.html |
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<H1><EM>Revelation13.net</EM></H1>
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<H2>Astrology, prophecies and predictions of the future for 2024 to 2030, Nostradamus, the Book of Revelation and Bible prophecy, the King James version English Bible code, New Age geography, Psychokinesis mind control of clouds and wind</H2>
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RUSSIAN PRESIDENT PUTIN IS THE ANTICHRIST 666 OF REVELATION 13 AND COULD START A NUCLEAR WAR SOON BECAUSE OF THE UKRAINE INVASION! Now that Ukraine is showing they can win this war, there is a great danger of Putin doing something drastic, such as launching nuclear weapons against Ukraine, NATO, and the West. Putin cannot stand losing the war and could launch atomic weapons or biological or chemical weapons against Ukraine and Europe. Putin is capable of anything. See below on why I say Putin is the Antichrist. So Putin is the most evil person on earth, The Beast 666, the Antichrist, in the Bible's Book of Revelation chapter 13. So Putin could set off nuclear weapons. And please aid Ukraine in any way you can in its battle with the evil one, the Antichrist Putin. Revelation 13 says about The Beast, also called The Antichrist: 13:7 "and it was given unto him to make war with the saints, and to overcome them".
(A master of war). 13:13 "And he doeth great wonders, so that he maketh fire come down from heaven on the earth in the sight of men." (Launching missiles with atomic weapons?) 13:18 "Here is wisdom. Let him that hath understanding count the number of the beast: for it is the number of a man: and his number is 666." The Antichrist is a Satanic imitation of Christ, Satan's man on earth. Christ was sent to save the world, the Antichrist was sent to destroy it.
<br><br>
Also consider this prophecy of Daniel:
<H3>Daniel 7, 8</H3> <br>
"7:1 In the first year of Belshazzar king of Babylon Daniel had a dream and visions of his head upon his bed: then he wrote the dream, and told the sum of the matters.<br>
3 And four great beasts came up from the sea, diverse one from another.<br>
4 The first was like a lion, and had eagle's wings: I beheld till the wings thereof were plucked, and it was lifted up from the earth, and made stand upon the feet as a man, and a man's heart was given to it.<br>
5 And behold another beast, a second, like to a bear, and it raised up itself on one side, and it had three ribs in the mouth of it between the teeth of it: and they said thus unto it, Arise, devour much flesh.<br>
6 After this I beheld, and lo another, like a leopard, which had upon the back of it four wings of a fowl; the beast had also four heads; and dominion was given to it.<br>
7 After this I saw in the night visions, and behold a fourth beast, dreadful and terrible, and strong exceedingly; and it had great iron teeth: it devoured and brake in pieces, and stamped the residue with the feet of it: and it was diverse from all the beasts that were before it; and it had ten horns.<br>
8 I considered the horns, and, behold, there came up among them another little horn, before whom there were three of the first horns plucked up by the roots: and, behold, in this horn were eyes like the eyes of man, and a mouth speaking great things.<br><br>
Note in this prophecy, which is about the Antichrist: the little horn: 3 of the horns, which are countries, are pulled out by the roots. The horns are the former satellites countries of Russia. So Ukraine may be the first invaded by Russia, and this is predicting that Russia will invade 2 others.
<br><br>
A quote relevant for our time:<br>
Charles Dickens, A Tale of Two Cities:
<br><br>
" It was the best of times, it was the worst of times. It was the age of wisdom, it was the age of foolishness. It was the epoch of belief, it was the epoch of incredulity. It was the season of light, it was the season of darkness. It was the spring of hope, it was the winter of despair. "
<br><br>
April 8 2024. Solar eclipse across the U.S.. 3 solar eclipses across the U.S. in 2017, 2024, and 2045. This Solar Eclipse could indicate a bad period for the U.S. in 2024. Look at what happened to the U.S. in 2017 when there was a solar eclipse across the U.S., the U.S. entered a dark 4 year period in 2017 ending on January 20 2021, that saw the COVID-19 epidemic, and almost ended up in dictatorship in the U.S. on January 6 2021. A previous solar eclipse that crossed the U.S. on June 8 1918 saw the U.S. in World War 1 and the 1918 Flu Epidemic. Also at this time there may be a bright comet, Comet 12P/ Pons-Brooks, also called the "Devil Comet" because it appears to have 2 horns, certainly a very ominous sign. It will likely be seen during this solar eclipse.
<br><br>
The Nov. 2024 U.S. Election. I am a Democrat myself, so I hope that a Democrat is elected U.S. President. But my forecast is, looking at Astrology signs, I think that Nikki Haley could be elected U.S. President in November 2024. One sign of this is Pluto entering the Astrology Sign Aquarius on January 20 2024, implying that Nikki Haley could win the Republican New Hampshire Primary on January 23 2024, getting a boost for the next primaries. Note that on Presidential Inauguration Day January 20 2025, that will be Nikki Haley's 53rd birthday.
<br><br>
WE ARE SEEING A POSITIVE FORCE IN THIS COUNTRY IN 2021 WITH THE ELECTION VICTORY OF PRESIDENT BIDEN, CONGRATULATIONS PRESIDENT BIDEN AND BEST WISHES IN 2024. <br>
Its great that President Biden was elected, this will result in a more positive and capable government for the United States compared to the previous 4 years. The January 6 2021 coup attempt could have ended democracy in the U.S. and turned the U.S. into a dictatorship. I think the force behind that coup attempt and the dark and disturbing things that have happened during 2017-2020 was the Antichrist Russian President
<a href="Putin.html">Putin</a> controlling the previous U.S. President. If the U.S. had been turned into a dictatorship on January 6, then this could have put the U.S,. under Putin's control in his attempt to take over the world. I think Putin was using his hypnotic mind control powers to control the previous President, and Putin could have taken control over the U.S..
<br><br>
Note that the US system of government based on a 3 branches (President, Congress, Supreme Court) was designed by the founding fathers after the Roman Republic, which had a Senate and 2 Consuls that were the equivalent of the President and Vice President today. The Roman Republic ended becoming an Empire with an Emperor after Julius Caesar crossed the Rubicon River (the boundary of Italy) with his army, which was an act of insurrection, to declare Civil War on the Roman government, eventually defeating it and installing himself as
dictator. After Caesar Rome became an Empire with an Emperor who had total control, including evil tyrants such as Nero. So January 6 was the equivalent of Caesar crossing the Rubicon, an attempted insurrection that if it had been successful would have ended the United States Republic, and made it an Empire with an Emperor. The Romans had the idea that the 3 branches would give the Republic form of government stability. The U.S. Capitol insurrection on January 6 was a close call, and the U.S. Republic was saved by the Capitol Police, the Judicial Branch - the Courts, Vice President Pence, General Milley Chairman of the Joint Chiefs of Staff, and some in the Senate (Thank You, Mitt Romney and Ben Sasse), and some in the House of Representatives, especially Nancy Pelosi. Otherwise the U.S. could have an Emperor today, with the U.S. no longer a Republic.
<br><br>A poem on the January 6 2021 Capitol Riot. Since the Capitol Riot was similar to the November 5 1605 Gunpowder Plot in London England, where there was an attempt to blow up Parliament and the King, I borrowed from a poem about it. The Gunpowder Plot poem begins:
"Remember, Remember, the fifth of November, the gunpowder treason and plot,
I know of no reason why the gunpowder treason should ever be forgot."
<br><br>
My poem:<br>
Poem on the January 6 Capitol Riot
<br><br>
The 6th of January, a day of anarchy, mob violence treason and plot,
I know of no reason why the Capitol treason should ever be forgot.
The mob planned murder and violence against the Senate House and Mike Pence,
To stop the electoral voting and have a dictatorship commence.
But Vice President Pence surprised them,
and voted in President Biden,
and thanks to Vice President Pence the Constitution survived them.
The murderous mob did contrive,
to murder Democrats and leave few alive,
but the nation survived.
<br><br>
World Population reaches 8 billion:<br>
Nov. 15 2022. World population reached 8 billion. Could relate to Revelation 8 and the opening of the seventh seal, could mean disasaters to soon come.
<br><br>
COVID-19:<br><br>
I wonder if COVID-19 may have been created by aliens to prepare for an alien UFO invasion (described below) within a few years. COVID-19 may be modifying human DNA, viruses can find their way into human DNA, in preparation for alien takeover. Note Revelation 2:10 "be thou faithful unto death, and I will give thee a crown of life". Crown of Life - could that be as a result of DNA changes from the Coronavirus? Could it be modifying human DNA in some unknown way? Note there was a movie "Omicron" about aliens on earth in the 1960s, could this indicate that the Omicron COVID variant is somehow modifying human DNA in preparation for the aliens coming. Even though Omicron has less severe illness, it could be doing something to DNA. COVID-19 B.1.617.2 Delta variant, first seen in India, the deadliest variant yet, relate to Revelation 16:17 and Revelation 16:13 where "unclean spirits" (the virus) come out of the mouth of the dragon (China). And it has the P681R mutation, at the 681st position on the virus, that makes it spread faster, relate to Revelation 6:8 the Fourth Horseman of the Apocalypse Death. Also note Delta name - Delta triangle shape below the circular virus shape, a keyhole, relate to Revelation 1:18 "keys of hell and death", and Revelation 20:1 "key of the bottomless pit." COVID has a key in the spike protein that enables it to enter the cell.
<br><br>
<a href="http://youtube.com/revelation13net">My videos on Youtube</a>.
<br><br>
<img src="PaintingCOVID19a.jpg">
<br><br>
My painting on COVID-19
<br><br>
PROPHECIES AND PREDICTIONS OF THE FUTURE FOR 2024 - 2030. THE END TIMES EVENTS AND DISASTERS COULD OCCUR IN 2024 - 2030: THE ANTICHRIST PUTIN IS ATTEMPTING TO TAKE OVER THE WORLD. THE FOUR HORSEMEN OF THE APOCALYPSE RIDING IN 2024 -2030.
IN 2024 - 2030 THE FOUR <a href="horsemen.html">HORSEMEN</a> OF THE APOCALYPSE RIDE: THE FIRST HORSEMAN THE ANTICHRIST 666 IS <a href="Russians.html">PUTIN</a>, THE SECOND HORSEMAN WAR (RUSSIA INVASION OF UKRAINE), THE FOURTH DEATH AS DISEASE EPIDEMIC SARS -LIKE COVID-19 CORONAVIRUS.
PUTIN THE THIRD ANTICHRIST OF THE NOSTRADAMUS PROPHECIES RISES TO POWER, THE FIRST TWO ANTICHRISTS WERE NAPOLEON AND HITLER.
3RD HORSEMAN ECONOMIC DISASTER.
SOON MAY COME
GIANT EARTHQUAKES, VOLCANOES, TSUNAMIS, GIANT SOLAR FLARES, MORE EPIDEMICS, WARS, MORE ASTEROIDS.
GIANT EARTHQUAKES AND VOLCANOES IN 2024-2030. WATCH OUT FOR GIANT VOLCANO ERUPTIONS AND EARTHQUAKES MAGNITUDE 7, 8 AND 9 AROUND THE WORLD IN 2024 - 2030.
<a href="Putin.html">PUTIN </a> THE ANTICHRIST IN RUSSIA IS ATTEMPTING TO TAKE OVER THE WORLD, DESTROYING NATO. PUTIN USES HIS HYPNOTIC MIND CONTROL POWERS TO CONTROL OTHERS.
A METEOR HITTING IN RUSSIA MAY RELATE TO THE ANTICHRIST RISING TO POWER THERE AS PUTIN. AN ASTEROID DEFENSE IS NEEDED, MORE MAY HIT SOON. SEE
<a href="asteroid.html">THIS PAGE</a>.
ALIENS LANDING ON EARTH BY 2030 MAY BE PROPHESIED IN BIBLE PROPHECIES AND NOSTRADAMUS PROPHECIES, SEE THE CALENDAR AND NOSTRADAMUS PAGES ON IT. SEE THE <a href="calendar.html">CALENDAR</a> PAGE ON THIS!
ALSO: RETURN OF CHRIST, BATTLE OF ARMAGEDDON, DEFEAT OF THE ANTICHRIST, POSSIBLE ALIEN UFO INVASION OF EARTH BY 2030! <br><br>
There are different methods of predicting the future - such as psychics who have psychic predictions where they actually see the future, Nostradamus was this psychic type of prophet. For my predictions I use Astrology, combined with Bible prophecy including the Book of Revelation, Nostradamus prophecies, and numerical methods. And for me there may be a psychic element also in my predictions for 2024 to 2030.
<br>
This web site includes a discussion of the Book of Revelation, the last chapter of the Bible, which includes a description of a catastrophic sequence of events that some people believe are occurring now, and may occur in
<a href="calendar.html">2024 - 2030</a>.
These include earthquakes (such as the giant Indonesia earthquake and
<a href="KingJames8b.html">tidal wave</a> in Dec. 2004 and the Japan magnitude 9 quake in 2011), wars, diseases
,
economic chaos, weather changes, and the rise to power of an evil dictator, called the Antichrist. He is identified by the number 666. Also in Revelation there are the
four horsemen of the Apocalypse -- the Antichrist, the conqueror, on a white horse; war, on a red horse; economic depression, on a black horse; and death rides a pale horse, and hell rides with him. The Four Horsemen of the Apocalypse are said to ride as the Antichrist rises to power. Also in Revelation, there are descriptions of angels, but the angel there can be an angel of death, carrying plagues. There is also a description in Revelation 8 of what appears to be an asteroid or comet hitting earth, destroying much of life on earth.<br>
In Revelation Chapter 1: John, on the island of Patmos near Greece, sees Christ, as he is exiled on this island after
the death of Christ. Christ appears among 7 golden candlesticks. This may be the John who was Christ's disciple, or it could be
another John. Christ shows John visions of events to occur in the distant future,
during a period of time in the future called the End Times.
Christ refers to himself as "Alpha and Omega" to John in this vision, and since Alpha in
<a href="Greek.html">Greek</a> represents the number 1, and Omega represents 800, this gives us a number of 801.
My painting shows Christ among the 7 golden candlesticks, with UFOs and an angel in the background. I believe there is a Christ - UFO connection, where Christ is an alien, refer to Revelation 19 on this, where Christ returns in the future leading a fleet of UFOs.
<br><br>
<img src="PaintingChrist.jpg">
<br><br>
<br><br>
IN AUGUST 1999 WHEN PUTIN FIRST ROSE TO POWER IN RUSSIA, THERE WAS A RARE GRAND CROSS ASTROLOGY PATTERN OF PLANETS IN A CROSS SHAPE, AND A TOTAL SOLAR ECLIPSE OVER EUROPE, INDICATING THAT PUTIN IS THE EVIL ANTICHRIST OF REVELATION 13 WHOSE NUMBER IS 666.
Putin is attempting to destroy NATO and take over the world. Do not underestimate Putin - Putin has hypnosis mind control powers he can use to control people, hypnotizing them by staring at them, his eyes are said to be intense and hypnotizing. Others who could hypnotize people with their gaze were Rasputin and Hitler.
<br><br>
<img src="PaintingRev13Beast.jpg">
<br><br>
September 2017. The <a href="atomic.html">Cassini </a> Saturn space probe crashed into Saturn/Satan. Cassini's connection to Putin: Putin first rose to power on August 9 1999.
Also then, the day of the Astrology Grand Cross in the sky: August 18 1999, was the day after Cassini, carrying Plutonium, passed close to earth.
And 1999 has 666 upside-down, 666 being the number of the Antichrist in Revelation 13.
This August 1999 Grand Cross, which is one of the most amazing astrological alignments ever seen in history, consisted of: the Sun, Venus, and Mercury in the sign of Leo, Mars and the Moon in Scorpio with Pluto close by in Sagittarius, Saturn and Jupiter in Taurus, and Neptune and Uranus in Aquarius. If Scorpio is considered to be the Eagle, and Aquarius the man, then we have the four beasts seen in Revelation 4 that sit at the throne in heaven, that have the faces of an eagle, a man, a lion, and a calf. This seems to indicate an important time for mankind; I think it may also relate to the rise to power of the Antichrist in year 2000 as Russian President Putin, especially since there was a cross pattern. Also, note that August 13, 1999 was Friday the 13th, said to be an unlucky day. Also note that August 9, 1999, was the 30th anniversary of the Charles Manson group's murder of Sharon Tate and others in Los Angeles, significant because of the Charles Manson group's Satanic-like cult. <br> Also: August 13 1999 was the significant future date on the Aztec Sun calendar from Mexico of 500 years ago, and August 13 1999 was predicted by the Aztecs to be an important day of change for mankind, that would change the world, as described in the book: "Day of Destiny, Where will you be on August 13 1999?", by John Mini, published 1998 by Trans-Hyperborean Institute of Science.<br><br>
Considering again Cassini going to Saturn: as for the planet Saturn, possibly Saturn represents "Satan"-- the Antichrist is said to be a Satanic imitation of Christ, actually the son of Satan. So the Cassini probe journey to Saturn actually may be the journey of mankind to "Satan". Also note that in
<a href="Greek.html">Greek</a>, where each letter is also a number, "Titan" totals 666, another indication of the Cassini landing on Titan being connected with the Antichrist. Note that Titan (representing the Antichrist?) revolves around Saturn/Satan. So Cassini crashing into Saturn on Sept. 15 2017 could relate to who was the U.S. President then.
</EM>
<br><br>
<EM> What's New:</EM> <br>
I am updating the
<a href="calendar.html">calendar</a> page and other pages for 2024, and adding more astrology charts.
<br><br>
Why do I say that Putin is the Antichrist of Book of Revelation chapter 13? There are many reasons why I am sure that Putin is the evil one who will bring about World War 3, that I discuss on the pages on <a href="Putin.html">
Putin </a> and <a href="Russians.html">Russia</a>. The biggest reason is that when Putin first rose to power there was an unusual Astrology pattern that also relates to a <a href="Nostradamus.html">Nostradamus </a>prophecy about the Antichrist. Let us consider the
Grand Cross Astrology pattern of August 1999. On August 18, 1999,
there was an unusual alignment of planets in a Grand Cross shape, possibly the most
unusual Astrological alignment seen in the last two thousand years. And one week
before, on August 11, 1999, there was a solar eclipse seen over Europe. The Grand
Cross, which is one of the most amazing astrological alignments ever seen in history,
consisted of: the Sun, Venus, and Mercury in the sign of Leo, Mars and the Moon in
Scorpio with Pluto close by in Sagittarius, Saturn and Jupiter in Taurus, and Neptune
and Uranus in Aquarius. The cross is a bent cross, relating it to the Antichrist, as the true cross relates to Christ.<br><br>
<img src="aug18.gif">
<br>
<br>
Concerning the solar eclipse over Europe on August 11, there is a prophecy by
Nostradamus that is of interest.
The Prophecies of Nostradamus predicted 3 Antichrists: the first was Napoleon, the second was Hitler, and the third I think is Russian President Putin.
Some of the Nostradamus prophecies do have dates, including
Century 10, Number 72:<br>
<br>
"In the year 1999, in the seventh month,<br>
from the sky there comes a great king of terror,<br>
to bring back the great king of the Mongols,<br>
Mars rules triumphantly, before and after"<br><br>
Concerning this prophecy by Nostradamus, it is interesting that the solar eclipse
passed over France on August 11,1999, and on August 17, 1999 the Cassini spacecraft
with its nuclear fuel passed within a thousand miles of earth's surface, within a day
of the Grand Cross pattern. I think the significance of Cassini passing by earth within
a day of the Grand Cross pattern is that Cassini may be a hologram, a symbolic
parallel event, related to the rise to power of the Antichrist in Russia as Vladimir Putin, President of Russia.
Note that the Cassini spacecraft reached Saturn in July 2004, and landed a probe on Saturn's moon Titan in Jan. 2005. "Titan" in Greek totals 666 (the number of the Antichrist), where in
<a href="Greek.html">Greek</a> each letter is also a number, and Greek is the language of the Book of Revelation and the New Testament. <br>
Note that Russian
President Putin began his rise to power in Russia in August 1999, at the time of the Grand Cross Astrology pattern and solar eclipse over Europe, becoming Prime Minister for Yeltsin (second-in-command in
Russia) on August 9, 1999. On December 31, 1999, Putin became Russia's President. And Mars is war - war will occur when Putin is in power. "King of the Mongols" - that Putin will be a tyrant rising to power in Asia.
<br><br>
Charles Manson has been in the news in recent years, he is an alleged mass murderer in prison for life in California. This may be significant in our discussion of the Antichrist Putin. Note that the Antichrist in Revelation 13 has the number of man, and 666. Man-son. And note that the Manson murders of Sharon Tate and others in LA California was on August 9, 1969. That was exactly 30 years before the Antichrist Putin became Prime Minister of Russia on August 9 1999, at the time of an August 11 1999 solar eclipse over Europe, and the August 18 1999 Grand Cross Astrology pattern of planets in a cross shape. And actress Sharon Tate who was murdered was the wife of Roman Polanski, who in 1968 had made a movie called "Rosemary's Baby" about the child of Satan. Also note that Charles Manson's cult lived in Death Valley in California, and Charles Manson included Book of Revelation prophecies in twisted form in his twisted philosophy.
<br><br>
April 25, 2014. The Prime Minister of Ukraine said he thinks Putin wants to start World War 3. I think he is correct, I think Putin could start World War 3 with a missile attack on the West in the near future.
<br>
At Armageddon, World War 3, of Revelation 16, there is a great nuclear war, I think started by Putin or China. The Antichrist is defeated by the returned Christ, as described in Revelation 19. The returned Christ (possibly returning by 2030) with his armies (of aliens and UFOs) may actually be an <a href="alieninvasion.html">invasion</a> of earth by aliens in UFOs, read Revelation 19 and it sounds like that. My painting of Christ leading a UFO alien invasion of Earth:
<br><br>
<img src="PaintingChristUFO2019.jpg">
<br><br>
A reason for invading earth may be that the aliens are concerned about global warming and earth's environment, refer to Revelation 11:18 "shouldest destroy them which destroy the earth".
And the New Jerusalem of Revelation 21 could be a giant alien city that comes down to earth after the alien invasion. Revelation 21 and 22 seem to be describing the reorganizing of earth by aliens. So Christ would be lead alien. And Nostradamus prophecies also prophesied alien invasion of earth and human genetics DNA modified for immortality, see
<a href="Nostradamus.html">this page</a>.
<br><br>
<img src="PaintingUFOInvasion1a.jpg">
<br><br>
(These paintings are by T. Chase. .)
<br><br>
<img src="PaintingChristUFO.jpg">
<br><br>
<img src="PaintingNJ10.jpg">
<br><br>
(Paintings by T. Chase - Christ returns on a UFO as described in Revelation 19. And the New Jerusalem is brought down to earth.).
<br><br>
<img src="NewJerusalemDrawing.jpg">
<br><br>
<img src="NewJerusalemDrawing2.jpg">
<br>
<br>
(The New Jerusalem is brought to earth by UFOs).
<br><br>
Years 2024-2030 could see the End Times events with the rise and defeat of the Antichrist, from my <a href="calendar.html">calendar</a> page:
<br><br>
And see the
<a href="calendar.html">calendar</a> pages on how a triangle pattern appeared on the sun on March 14 2012 when there was a 999 (666 upside-down) grand trine triangle astrology pattern, after the March 4 election of
<a href="Putin.html">Putin</a> the Antichrist in <a href="Russians.html">Russia</a>. Does Putin the Antichrist 666 have power over the sun? Revelation 13:13 (King James version) on the Antichrist: "And he doeth great wonders, so that he maketh fire come down from heaven on the earth in the sight of men." Solar flares? Putin was reelected as Russian President on March 4 2012, and 2 days later March 6 the sun sent a solar flare towards earth. See <a href="Russians.html">this page</a> on Putin's connection to Ra the Egyptian sun deity. And the Cold War appears to be returning, with Putin returned as Russian President, a Russian General having made threats in May 2012 of a nuclear strike against NATO ABM Anti Ballistic Missile sites being deployed in Eastern Europe. Revelation 13:13 (King James version): "And he doeth great wonders, so that he maketh fire come down from heaven on the earth in the sight of men." So could Revelation 13:13 be about Putin (or North Korea) launching a nuclear missile strike on Europe or the U.S., starting World War 3 in the future? Or could this be about Putin causing giant solar flares to hit the earth?
<br><br>
Note: One reason why a Southern California large earthquake has not occurred is because there may be an alien UFO base off the coast of Los Angeles (LA), and the aliens may be preventing a Southern California San Andreas Fault quake which could damage their underwater base. They may be slowly releasing the earth stress to prevent a quake there. A lot of UFOs have been seen entering and leaving the deep water off the coast of L.A., so its very likely they have an underwater base there. Therefore it is unlikely there will be a major Southern California Quake in future years. Controlling earthquakes is easy for these aliens.
<br><br>
In this site Revelation13.net, my method of prophecy combines
Astrology and other New Age Schools, mythology,
religion, the prophecies of
<a href="Nostradamus.html">Nostradamus</a>, Bible Code in the <a href="KingJames.html">King James</a> Bible, Bible prophecy, and
<a href="int666.html">numerical analysis</a>. In particular, the
<a href="Apocalypse.html">Book of Revelation</a> of the King James Bible is discussed. This web site is huge, you can spend days reading it. The
emphasis of this web site is on predicting the future for years
<a href="calendar.html"> 2024 - 2030</a>. There could be ominous events possibly occurring in 2024 - 2030: quakes, volcanoes, Flu or SARS -like Coronavirus (2020) epidemic, and wars.
This is a new
holistic method of prophecy I have developed. Also on this web site are videos on
<a href="psychic.html">Psychokinesis</a>, where I demonstrate using Psychic Energy to control the weather, clouds and wind, by psychic ESP mind over matter power, telekinesis, making clouds grow or disappear and controlling the wind.
<br>
I will give
a detailed description of my theories in this web site.
Also
discussed
here:
<a href="economy.html">economic</a> predictions and the Stock Market,
predictions of world events for
this year and future years.
Note that Revelation 6:8 is about the Fourth Horseman, Death, so will Death ride in 2024-2030 as a worldwide epidemic, likely as the COVID-19 Coronavirus?
<br><br>
<img src="Painting4thhorseman.jpg">
<br><br>
Above: my painting of the Fourth Horseman, and Hell also riding with him.<br> <br>
Also, the Astrological events of
<a href="atomic.html">August 1999</a> (a solar eclipse seen in Europe and a rare alignment of planets in a cross shape) is discussed.
Possible Antichrist sighting: I think the Antichrist is the Russian President elected in March 2000, Vlad
<a href="Russians.html">Putin</a>, and the Red Dragon that Putin the Antichrist will be allied with is
<a href="China.html">China</a>, as well as Iran. And the planetary alignment of
<a href="polar.html">5/5/2000 </a>with the sun and planets on one side of the earth is discussed, note that Vladimir Putin was inaugurated as President of Russia 2 days later on May 7, 2000.
And on November 4 2003 there was the largest solar flare ever seen, when Putin was in Rome, and on Nov. 8 there was a lunar eclipse and a grand sextile hexagon shaped astrology pattern, again indicating Putin is the Antichrist; apparently Putin visiting Rome, which is connected with the Antichrist in Bible prophecy, resulted in a tremendous Satanic force that resulted in the giant solar flare on Nov. 4 2003, see
<a href="Putin.html">this page</a>. And the possibility of a doomsday
<a href="asteroid.html">asteroid</a> or comet collision with earth is discussed, note that in 2002 there were several asteroid near-misses with earth; and a King James Bible Code matrix may predict an
<a href="KingJames11.html">asteroid hit in the ocean </a>within a few years, causing a giant tidal wave. A suggestion: a great economic stimulus project would be to build an asteroid defense for earth, for a few billion $ NASA could build an asteroid defense using interceptor rockets, and this would create jobs in the U.S..
<br>
Also, on this web site, other prophet's
<a href="prophecies.html">prophecies</a> are discussed, other Bible
<a href="prophecy.html">prophecies</a>.
<br>
And watch my
<a href="http://www.youtube.com/Revelation13net">videos</a>
on the subjects discussed here, including the King James version English Bible Code, prophecies of the future, Nostradamus, and other subjects.
<br>This web site used Codefinder Millennium Edition Bible Code software. <br>
Generally, on this web site astrology, new age methods, numerical analysis, religion, and mythology are combined to explain the world today, and to predict the future.
<br><br>
<STRONG>To go to the section:</STRONG><br><br>
<EM>Predictions for the near future:</EM><br>
<A HREF="#PRED">Predictions</A> of world events<br>
<A HREF="calendar.html">Calendar</A> of dates, past and future<br>
<A HREF="economy.html">Economy</A> and Stock Market<br>
<a href="alieninvasion.html">Alien</a> invasion soon? <br><br>
<EM>Number and time patterns:</EM><br>
<A HREF="int666.html">666</A> Day Intervals and other time cycles<br>
<A HREF="Julian.html">The Julian</A> Day Count<br>
<A HREF="Greek.html">Number patterns</A> in Greek, the original language of the Bible's Book of Revelation and the New Testament<br>
<A HREF="Hebrew.html">Number patterns</A> in Hebrew, the original language of the Old Testament</A>
<br>
<A HREF="ASCII.html">ASCII</A> number patterns<br><br>
<EM>Astronomy and Earth Science:</EM><br>
<A HREF="supernova.html">The Southern Cross</A> Effect and the 1987 supernova<br>
<A HREF="Carinae.html">Eta Carinae</a>, the giant Southern Hemisphere star, could it become a giant supernova soon?<br>
<A HREF=comets.html>Comet Hale-Bopp</A>, Comet Hyakutake, and could there be another bright <A HREF="comet.html">comet</A> soon?<br>
<A HREF="astronomy.html">Prophecy patterns</A> in Astronomy<br>
<A HREF="asteroid.html">Could a comet</A> or asteroid hit earth?<br>
<A HREF="sun.html">Could a giant solar flare</A> scorch the earth?<br>
<A HREF="earthquake.html">Predictions on earthquakes</a>, volcanoes, tsunami tidal waves<br>
<br>
<EM>Diseases:</EM><br>
<A HREF="#DISEASE">Astrology/ New Age discussion of diseases:</A>
<a href="Ebola.html">Ebola</a>,
<a href="Flu.html">Flu</a>,
<a href="AIDS.html">AIDS</a>, Mad Cow Disease
<a href="SARS.html">SARS and 2020 COVID-19 Coronavirus </a>, <a href="Smallpox.html">Smallpox</a><br>
<A HREF="foot-and-mouth.html">Foot-and-mouth disease</A> in sheep, cattle, and pigs and England, "the slaying of the lamb"<br><br>
<EM>People:</EM><br>
<A HREF="Diana.html">Princess Diana</A> and Prince Charles, and Prince Harry and Meghan Markle<br>
<a href="KingJames2b.html"> Pope</a> John Paul II and Pope Benedict XVI<br>
<br>
<EM>The world</EM>:<br>
<A HREF="geography.html">New Age geography - country shapes and land area related to Revelation</A><br>
<A HREF="geographic.html">Patterns</A> of geographic coordinates<br>
<A HREF="population.html">Patterns</A> of world and country populations<br>
<A HREF="Russians.html">Russia</A>, Feet of a Bear: is Russian President Putin the Antichrist?<br>
<A HREF="Putin.html">Russian</A> President Putin more on why he may be the Antichrist.<br>
<A HREF="Hitler.html">Hitler</A>, predecessor to the Antichrist<br>
<A HREF="China.html">China</A>, the Dragon: And the dragon gave him his power, and his seat, and great authority<br>
<A HREF="Iraq.html">Iraq</A><br>
<A HREF="war.html">The 9/11/2001 </a> attack on the U.S.<br>
<A HREF="Osama.html">More on</A>Terrorism, and Major Terrorists
<br>
<A HREF="Europe.html">Europe</A>, <br>
<A HREF="Israel.html">Israel</A><br>
<A HREF="places.html">Places</A> to visit: cathedrals, churches, New Age sites, other places of interest<br>
<br>
<EM>Ghost or spirit photos at:</EM><br>
<A HREF="Salem.html">Salem MA</A><br>
<A HREF="Gettysburg.html">Gettysburg PA</A>
<br><br>
<EM>Astrology alignments:</EM><br>
<A HREF="atomic.html">August 1999 Grand Cross</A> Astrology alignment and the Cassini Spacecraft fly-by near Earth, and the Rise of the Antichrist Putin; King James version Bible Code on it; and 6-6-6 Degree Astrology patterns<br>
<A HREF="polar.html">May 5 2000</A> planetary alignment, did it announce the rise of the Antichrist in Russia?<br>
<A HREF="triangleonsun.html">March 14 2012</A> triangle astrology pattern when a triangle was seen on the sun, Antichrist related<br>
<A HREF="December212012.html">December 21 2012</A> Mayan calendar date<br>
<a href="astrologycharts.html">Astrology charts</a>
<br>
<br>
<EM>Other subjects:</EM><br>
<A HREF="shroud.html">The Shroud of Turin</A><br>
<A HREF="Mary.html">Virgin Mary sightings</a>, including at Milton Hospital in Massachusetts and Clearwater Florida<br>
<A HREF="atom.html">Patterns</A> in Chemical Elements<br>
<A HREF="movie.html">A discussion of recent movies</A>, and prophecy<br>
<br>
<EM>Prophecies: Bible and other:</EM><br>
<A HREF="Apocalypse.html">Description of sections</A> of the Book of Revelation<br>
<A HREF="horsemen.html">The Four Horsemen</a> of the Apocalypse<br>
<A HREF="prophecy.html">Other Bible prophecies</A><br>
<A HREF="Nostradamus.html">The Prophecies of Nostradamus</A>, do they indicate the Antichrist is Russian President Putin?<br>
<A HREF="prophecies.html">Prophecies of others</A>, from the past<br><br>
<EM>Pages on the King James version English Bible code, with matrices I generated myself and analysis:</EM><br>
<A HREF="KingJames.html">Page 1</a>: The First Page Introduction on the King James Bible Code<br>
<A HREF="KingJames1a.html">Page 1a</A>: Russia and President Putin; the U.S.; Osama bin Laden and Al Qaida
<br>
<a href="KingJames1c.html">Page 1c</a>: Jesus Christ as Messiah<br>
<a href="KingJames1d.html">Page 1d</a>: The Two Witnesses<br>
<a href="KingJames1e.html">Page 1e</a>: Russia invading Ukraine in 2014 and 2022<br>
<a href="KingJames1f.html">Page 1f</a>: North Korea and China <br>
<a href="KingJames1i.html">Part 1i</a>: United States Civil War of 1860 - 1865
<br>
<a href="KingJames1j.html">Part 1j</a>: The New Russians Submarines and Missiles to threaten NATO and the U.S.
<br>
<a href="KingJames1k.html">Part 1k</a>: Brexit UK leaving the EU
<br>
<a href="KingJames1l.html">
Part 1l</a>: Japan and the Honjo Masamune, the missing Samurai Sword
<br>
<a href="KingJames2.html">Page 2</a>: Princess Diana<br>
<a href="KingJames2b.html">Page 2b</a>: Pope John Paul II, Pope Benedict XVI, Pope Francis<br>
<a href="KingJames2d.html">Page 2d</a>: The 2005 Election in Germany and Angela Merkel<br>
<a href="KingJames2g.html">Page 2g</a>: The JonBenet Ramsey Unsolved Murder Case
<br>
<a href="KingJames2i.html">Page2i</a>:
Percy Fawcett who went missing in the Amazon jungle in the 1920s<br>
<a href="KingJames3d.html">Page 3d</a>: Iran and Nuclear Weapons
<br>
<a href="KingJames4.html">Page 4</a>: The U.S. Presidential Elections in 2004 and 2000<br>
<a href="KingJames4a.html">Page 4a</a>: President Obama reelected in 2012
<br>
<a href="KingJames4b.html">Page 4b</a>: On Joe Biden and Kamala Harris, elected President and Vice President in November 2020<br>
<a href="KingJames4c.html">Page 4c</a>: Vice President Mike Pence
<br>
<a href="KingJames6.html">Page 6</a>: Cold Fusion, can it generate nuclear power? Can it power Time Travel? <br>
<a href="KingJames6a.html">Page 6a</a>: String Theory, M-Theory, other dimensions, and a Unified Theory of Everything.<br>
<a href="KingJames6c.html">Part 6c</a>: Increased Earthquakes and Volcanos around the World <br>
<a href="KingJames7.html">Page 7</a>: A Nuclear Fission reactor in Earth's Core?<br>
<a href="KingJames8.html">Page 8</a>: Could a volcano in the Canary Islands result in a giant tidal wave hitting the U.S. and Europe? And could Yellowstone in Wyoming explode as a supervolcano?<br>
<a href="KingJames8a.html">Page 8a</a>: Could a giant magnitude 8 earthquake shake the San Andreas Fault in California, in the near future? Or a giant tidal wave hit California?<br>
<a href="KingJames8b.html">Page 8b</a>: The Magnitude 9 Earthquake and Tidal Wave off Indonesia in December 2004.<br>
<a href="KingJames8c.html">Page 8c</a>: A Giant Earthquake on the New Madrid Fault Line in the Central U.S.?<br>
<a href="KingJames8d.html">Page 8d</a>: Hurricane Katrina hits Florida, Louisiana, and Mississippi in 2005<br>
<a href="KingJames8e.html">Page 8e</a>: Earthquake in Japan<br>
<a href="KingJames8f.html">Page 8f</a>: Will Mount Rainier in Washington state erupt soon? Will the Hekla Volcano or Katla Volcano in Iceland erupt soon?<br>
<a href="KingJames9a.html">Page 9a</a>: How will the stock market and world economy do?<br>
<a href="KingJames10.html">Page 10</a>:
Ebola Disease, the deadly virus of Africa; could it cause a worldwide plague? Also, AIDS and HIV, Mad Cow Disease (BSE), Influenza (bird flu or swine flu), COVID-19.<br>
<a href="KingJames10a.html">Page 10a</a>: Autism in children<br>
<a href="KingJames10b.html">Page 10b</a>: Cancer<br>
<a href="KingJames10c.html">Page 10c</a>: Alzheimer's Disease<br>
<a href="KingJames10d.html">Page 10d</a>: on the Aging Gene TOR, and DNA Telomeres and Aging<br>
<a href="KingJames11.html">Page 11</a>: Could an
asteroid or comet hit earth soon ( an ocean impact, 7 pieces, 7 hits, tidal wave), causing an Extinction Level Event (ELE)?<br>
<a href="KingJames11a.html">Page 11a</a>: Gamma Ray Bursts (GRB)<br>
<a href="KingJames12.html">Page 12</a>: Two Southern Hemisphere stars that I relate to prophecies: the 1987 supernova and the giant star Eta Carinae.<br>
<a href="KingJames12a.html">Page 12a</a>: Is there Life outside Earth in our Solar System - on Mars, Europa, or Titan? Are Flying Saucers and Aliens for real? Men in Black. W56 UFOs and Aliens. The Nazca Lines in Peru, a sign of Alien Visitors? President Obama and Aliens. George Adamski who saw Aliens and UFOs in the 1950s.
<br>
<a href="KingJames13.html">Page 13</a>: A Jean Dixon prophecy <br>
<a href="KingJames14.html">Page 14</a>: Nostradamus prophecies are interpreted by the Bible Code<br>
<a href="KingJames14a.html">Page 14a</a>: John Titor and his story of time travel and prophecies. He said he was from year 2036.<br>
<a href="KingJames14b.html">Part 14b</a>: On the Mayan Calendar Date December 21 2012, and the Crystal Skulls
<br>
<a href="KingJames15.html">Page 15</a>: The Bible Code related to "The Da Vinci Code" (the book by Dan Brown), the Knights Templar, and the Mary Magdalene mystery. <br>
<a href="KingJames15a.html">Page 15a</a>: Crop Circles and the Bible Code, and the rise of the Antichrist.<br>
<a href="KingJames16.html">Page 16</a>: The Voynich Manuscript; can the Bible Code decode this strange document?
<br>
<a href="KingJames16a.html">Page 16a</a>: The Indus Script, a language from ancient India that is still not deciphered<br>
<a href="KingJames16b.html">Page 16b</a>: Megaliths and Stonehenge, Gobekli Tepe<br>
<a href="KingJames16c.html">Page 16c</a>: The undeciphered language Linear A of Crete, and the Etruscans of Italy, and Easter Island and Aliens
<br>
<a href="KingJames16d.html">Page 16d</a>: The Legend of the Continent of Atlantis<br>
<a href="KingJames16e.html">Page 16e</a>: Oak Island in Canada where there may be buried treasure<br>
<a href="KingJames17.html">Page 17</a>: Human Evolution and Neanderthal Man, and is the Human Brain a Quantum Computer?<br>
<a href="KingJames17a.html">Page 17a</a>: Strange Creatures: Bigfoot, the Abominable Snowman, the Loch Ness Sea Monster<br>
<a href="KingJames17b.html">Page 17b</a>: Psychic ESP Telekinesis Mind over Matter Power<br>
<a href="KingJames17c.html">Page 17c</a>: Zombies<br>
<a href="KingJames17d.html">Page 17d</a>: The Rapture<br>
<a href="KingJames17e.html">Page 17e</a>: Reincarnation and Past Lives<br>
<a href="KingJames17f.html">Page 17f</a>: 3 Psychics - Edgar Cayce, Jeane Dixon, Leslie Flint<br>
<a href="KingJames18.html">Page 18</a>: Doctor Who the Science Fiction TV Series
<br>
<a href="KingJames19.html">Page 19 </a>: on Famous Artists: Da Vinci, Van Gogh, Vermeer
<br><br>
Videos:<br>
Watch my
<a href="http://www.youtube.com/Revelation13net">videos</a>
on subjects discussed on this web site: the King James version English Bible Code, Nostradamus prophecies, AIDS disease, John Titor the Time Traveler, Cold Fusion Nuclear Power, Bible prophecy, prophecies of the future for the next 10 years, New Age Geography, and many other subjects.
<br><br>
<EM>Books and links:</EM><br>
<A HREF="books.html">Recommended books</A> and web sites<br>
<br><br>
<EM>Psychic and Dreams:</EM><br>
<A HREF="dreams.html">Dream Log:</a> Dreams I have had. <br>
<A HREF="psychic.html">Psychic</A> Psychokinesis Powers of Weather Control are demonstrated in videos I made, making clouds grow and disappear and controlling the wind.<br>
<A HREF="psychic1.html">Page 2</a> on Psychokinesis Weather Control<br>
<A HREF="psychic2.html">Page 3</a> on Psychokinesis Weather Control<br>
<A HREF="psychic3.html">Page 4</a> on Psychokinesis Weather Control<br>
<br><br>
<EM>Feedback:</EM><br>
<A HREF="comments.html">Some emails</A> I have received
<br><br>
<EM>Linking to this site:</EM><br>
<A HREF="banners.html">Linking to this site</A>. <br><br>
Email T. Chase at: tchase800@aol.com
<br>
<br>
<A NAME="PRED"> </A>
<STRONG>Predictions for 2024 - 2030:</STRONG><br>
(1)1998=666x3, and 1999 has 666 upside down, and 666 is the number of the Antichrist
(also called The Beast) in
Revelation 13, I believe these numbers are connected with his appearance in year 2000 (as Russia's President Putin), and there will be a powerful satanic influence in the world (related to Putin) in 2024 - 2030, that relates to the rise of the Antichrist Putin.
Revelation is the last chapter of the Bible, and includes a
series of prophecies of catastrophic events-- wars, earthquakes, diseases,
<a href="economy.html">economic</a> chaos, and the arrival of the
Antichrist. Angels are also mentioned in Revelation, such as an angel from the East in Revelation 7, another Angel in Revelation 10.
As described in
the prophecies of Revelation, the
Antichrist is the son of Satan, a Satanic imitation of
Christ. The Antichrist will be assisted
by the False Prophet, who is the Second
Beast of Revelation 13. The False Prophet is said to work
apparent miracles, including "bringing fire down from
heaven". The Antichrist is described as having the mouth of a lion, feet of a bear, and gets his power from the dragon: the bear is Russia, the dragon is Red China and also Satan, and the mouth of a lion I think is Hong Kong, the former British colony that is now part of China. This indicates a Russia-Red China military alliance. A second meaning of the lion is
<a href="KingJames3d.html">Iran</a>, where before the Islamic Revolution Iran had a Lion on its flag, indicating a Russia-China-Iran military alliance, with Iran supplying military drones to Russia. The "mouth of a lion" could be Iran.
"The little horn" is a name for the Antichrist from the Book of Daniel (note Putin's small size), so St. Petersburg Russia is where this little horn of the red beast has grown.<br> <br>
<img src="Russia666.gif">
<br><br>
Alternative lion/bear/dragon: Russia-Iran is the bear-lion beast that sits on the dragon China, and gets its economic power from China.
<br><br>
<img src="RussiaIranChina.jpg">
<br><br>
Also note Revelation 16:12, where the River Euphrates in Iraq is dried up by the sixth angel, so that an army from China ("the King of the East") can cross to the Battle of Armageddon, World War 3. Note China's increasingly strong military, now second only to the U.S.. World War 3 could be started by China. See my painting on this:
<br><br>
<img src="PaintingChinaarmy.jpg">
<br><br>
And in this painting by me from Revelation 16 are shown 3 angels who turn rivers and the sea to blood, and have the sun scorch the earth with fire.
<br><br>
<img src="Painting3angelsa.jpg">
<br><br>
And in this painting by me, referring to Revelation 8 and 15, are shown 7 angels, who result in lightning and there is a sea of fire and glass.
<br><br>
<img src="Painting7angels.jpg">
<br><br>
(2) A key sign in 1998-99 that could relate to the arrival of
the Antichrist was on April 23, 1998, (and also Feb. 23, 1999) when
the planet Venus
approached close to Jupiter in the sky. Jupiter relates to
the Antichrist, because Jupiter and Thor (the Scandinavian
equivalent) are said to control lightning and thunder, and
the Antichrist is said to bring "fire down from heaven",
which sounds like lightning. Venus having a close conjunction to
Jupiter could mean Jupiter is "lit" by the close approach
of Venus. There was a similar but much closer approach of
Venus to Jupiter on June 17, 2 B.C., near the time of birth
of Christ; the 2 planets actually appeared to merge in the
sky. This could have accounted for the Star of Bethlehem
legend; the 3 wise men were Astrologers, and such an
unusual planetary conjunction would have had great
significance for them. So, these similar conjunctions in
1998 and 1999, and on February 1 2008 a close approach of Venus and Jupiter to within .5 degree, could mean the Antichrist rose to power in 2000 and I think he is Russian President Putin. And note that on May 17, 2000 Venus and Jupiter also had a very close conjunction, only 4' apart, but were too close to the morning sun to be seen. And note that on Nov. 4, 2004, Venus passed within .6 degree of Jupiter. Also on July 1 2015 there was a close conjunction in the sky of Venus and Jupiter, and on on October 28 2015 a close conjunction of Venus, Jupiter, and Mars.<br>
Also of interest was the
<a href="polar.html">5/5/2000</a>
grouping of the planets on one side of the earth: the 5/5/2000 alignment may be just another sign of the rise of the Antichrist, note that President Putin was inaugurated as President of Russia 2 days later on May 7, 2000. <br>
Possibly the Antichrist was elected as Russian President Putin in the spring of 2000. See the
<a href="Russians.html">Russia</a> section for a discussion of this and some interesting facts on President Vladimir Putin. Also indicating
<a href="Putin.html">Putin</a> is the Antichrist: Putin visited Rome on November 4 2003, on the day there was the largest solar eruption from the sun in history. And November 8 2003, during a lunar eclipse, there was a hexagon astrology pattern (6 sides, as in 666) that I relate to the Antichrist Putin, also on the
<a href="Putin.html">Putin</a> page.
<br>
Another way Putin will come to world power as the Antichrist is by controlling the world's Natural Gas reserves, Russia having the world's largest Natural Gas reserves. <br>
But I think an event frequently discussed in Biblical Prophecy called "The Rapture" will not occur, because this is a misinterpretation of Biblical prophecy by innumerable writers and preachers. Supposedly "The Rapture" would occur during or just before the rule of the Antichrist, and would be an instantaneous disappearance of millions of Christians around the world, leaving other people behind, and it is described as a joyous event where they will all go to heaven together. I think this will not happen, because these writers and preachers are not correctly interpreting Bible prophecy. I think we are in the End Times, but the Rapture will not occur.
Or The Rapture could be related to aliens, possibly a mass alien abduction of millions of people, possibly related to an alien invasion of earth that could occur within a few years, see the calendar page on it.
<br>
<br>(3) Significant dates, see the
<a href="calendar.html">calendar </a>section for more:
<br>
<br>
(4) <a href="economy.html"> Economic recession</a> or depression
in the world economy in 2024-2027, the 3rd horseman economic disaster riding;
I believe that 4 of the Planets
correspond to the <a href="horsemen.html">
Four Horsemen of the Apocalypse</a>
in
Revelation; Jupiter is the Antichrist, Mars is War, Saturn
is Economic Depression, and Pluto is Death (and Hell rides
with Death, Pluto has a single moon Charon, which like
Pluto has a mythology connected with the Land of the Dead.)
Saturn I would relate to economic depression, because in
Greek / Roman / Etruscan mythology, Saturn was associated with
agriculture as well as weights and measures and coins. So, there could
be worsening world economic problems in 2024-2030, caused by the Coronavirus epidemic. <br>
(5) War. War could be a worsening problem in 2024-2030 China could start a war by invading Taiwan. Russia could continue invading Ukraine and possibly other former Soviet Union countries to incorporate into Russia and start World War 3 by launching missiles. General war in Europe or World War 3 is possible. In the Middle East also.
Russia has threatened a missile strike on NATO and the U.S., and North Korea has threatened to launch a missile strike on the U.S..
So Russia or China could start a nuclear war.
There is also concern over the Second Horseman War riding in 2024-2030.
<br>
(6) The Cassini spacecraft passed by earth on August 17, 1999, on the same day as a <a href="atomic.html">
Grand Cross Astrology pattern</a>,
the most unusual Astrology pattern of the last 2000 years. The planets aligned in a cross shape. And that was a week after a solar eclipse over Europe. Note that Vladimir Putin became Prime Minister in Russia in August 1999, this Grand Cross and eclipse may relate to Putin's rise to power as the Antichrist, and the Cassini probe to Saturn/Satan may be a holographic parallel to Putin's rise to becoming Antichrist. Since the Cassini spacecraft landed a probe on Titan in Jan. 2005, this could be related to the rise of the Antichrist (Putin), note that Titan in Greek (the language of the Book of Revelation) totals 666, see
<a href="Greek.html">this page</a> on Greek. <br>
<br>
<br>
(7) Diseases. Disease epidemics in 2024-2030, with the Coronavirus pandemic or Flu. The Fourth Horseman of the Apocalypse Death riding.
<A NAME="SOUTHERNCROSS"></A>
<br>
(8) The Southern Cross effect. In 1987 there was a
Supernova in the Southern Hemisphere sky, "igniting"
astrologically the positive influence of a nearby
Constellation, the Southern Cross. This began a positive
sequence of events in the Southern Hemisphere, with
Democracy coming to South America after that, and positive
change to South Africa. <br>
But the
Northern Hemisphere could see problems, related to the
economy, war, natural disasters, diseases; the Four Horsemen riding in 2024- 2030. In 1993 there was a Supernova
in the Northern Hemisphere Great Bear Constellation, and
since Draco the Dragon is a constellation close to it, and
the Dragon is Satan in Biblical symbolism, this began a
negative influence over the Northern Hemisphere, which will
likely continue. So the Northern Hemisphere will likely
see problems with earthquakes, volcanoes, diseases, wars,
weather changes, economic problems, the rise of the Antichrist in Russia, terrorist attacks.
<br><br>
<A NAME="COMET"> </A>
(9)Comets. We have seen bright
<a href="comets.html">comets</a>
in 1996 and 1997,
and I think there could be another bright comet in 2024-2030.
<br>
As Comet
Hale-Bopp peaked in April 1997, there was a fire in April
1997 in the Cathedral holding the Shroud of Turin in Italy,
but the
<a href="shroud.html">Shroud</a>
fortunately escaped damage, due to the
bravery of a Turin firefighter. The Shroud of Turin is
believed by many Christians to be the burial cloth of
Christ. Recent carbon tests seemed to indicate it was a
fake, but those tests are considered by many people to be
invalid because: (1) there was bacteria growth on the cloth
that invalidated the measurements (2) a previous fire in
1532 resulted in carbon deposits on the cloth that
invalidated the recent carbon tests. So, the cloth could
be the real burial cloth of Christ, bearing his image on
it. What is interesting, is that at the time of the
previous shroud fire, there were three bright comets in 3
years, in 1531-1533. And at that time, there was the
greatest schism in the history of Christianity, with the
Protestant Reformation of Martin Luther. The shroud was
slightly damaged, but repaired, then. Maybe the three
comets of 1531-1533 represented the Holy Trinity: the
Father, the Son, and the Holy Ghost. So, that is why I
would not be surpised if there is a third bright comet in
2024 - 2030, but this time the comets could represent the
Unholy Trinity of Revelation: satan, the Antichrist, and
the False Prophet.
April 8 2024, Solar eclipse across the U.S.. 3 solar eclipses across the U.S. in 2017, 2024, and 2045. This Solar Eclipse could indicate a bad period for the U.S. in 2024. Look at what happened to the U.S. in 2017 when there was a solar eclipse across the U.S., the U.S. entered a dark 4 year period in 2017 ending on January 20 2021, that saw the COVID-19 epidemic, and almost ended up in dictatorship in the U.S. on January 6 2021. A previous solar eclipse that crossed the U.S. on June 8 1918 saw the U.S. in World War 1 and the 1918 Flu Epidemic. Also at this time there may be a bright comet, Comet 12P/ Pons-Brooks, also called the "Devil Comet" because it appears to have 2 horns, certainly a very ominous sign. It will likely be seen during this solar eclipse.
<br>
An interesting aspect of Comet Hale-Bopp was that it was
discovered independently by two men on the same day, July
23, 1995, in towns of New Mexico and Arizona, at the same
exact latitude North:<br>
Alan Hale-- Cloudcroft, NM 32.96 N 105.75 W<br>
Thomas Bopp-- Stanfield, AZ 32.88 N 111.96 W<br>
I think the message
here is that, near the midpoint between these two
locations, is the town of Lordsburg, New Mexico, a name
with a Biblical message. One way to consider numbers, in a
religious sense, is to convert them to Biblical passage
numbers. The midpoint is at 108.85 W, and if you consider
Biblical Psalm passage 108:4,5 you have (King James
Version): "For thy mercy is great above the heavens, and
thy truth reacheth unto the clouds. Be thou exalted, O
God, above the heavens: and thy glory above all the earth."
So this Bible passage fits a comet, certainly.<br>
If you consider the 2 states of discovery, Arizona has a
New Age connection, since Sedonna Arizona is this country's
New Age center. And Arizona's Feb. 14 birthday makes it an
Aquarius, the sign with a New Age connection. New Mexico,
however, is Capricorn. I think that that Arizona may
represent the New Age movement, while New Mexico represents
traditional Christianity; these may be the two tails (Blue
and White) of comet hale-bopp.
Both the New Age movement and Chrisitianity have Millenial
Movements. And the twin discoverers-- note that one of the
beliefs in some early Christian writings was that Jesus had
a twin brother, Thomas, who supposedly ended up in India,
giving him sort of a New Age connection. This, I think, is the message of
Comet Hale-Bopp. <br>
If there is a
<a href="comet.html">third bright comet</a> in year 2024-2030, I would not
be surprised if it is red in color.
<br>
(10) Europe and Russia, .
<br>
A woman rides the beast in Revelation 17, I think this is
<a href="Europe.html">Europe-- Europa</a>,, since Europa in mythology was a woman riding a bull. Putin exerts much influence over Europe by controlling natural gas supplied by Russia to Europe.
Eventually the beast will turn against Europe and burn Europa with fire, as in Revelation 17. Possibly nuclear, and biological attacks on Europe by Russia. In Revelation 17:<br>
17:3 "...and I saw a woman sit upon a scarlet coloured beast, full of names of blasphemy, having seven heads and ten horns."<br>
17:12 "And the ten horns which thou sawest are ten kings, which have received no kingdom as yet; but receive power as kings one hour with the beast."<br>
17:16 "And the ten horns which thou sawest upon the beast, these shall hate the (woman), and shall make her desolate and naked, and shall eat her flesh, and burn her with fire."<br>
<br><br>
(11) The Two Witnesses.
The Two Witnesses are two prophets who will appear during the end times events. They give prophecies seen over the internet and TV around the world. The beast kills them, but after three days they are resurrected and rise up into a cloud, which I think is a UFO. People are terrified when this happens.<br><br>
"11:3 And I will give power unto my
two witnesses, and they shall prophesy a thousand two hundred and threescore days, clothed in sackcloth.<br>
4 These are the two olive trees, and the two candlesticks standing before the God of the earth.<br>
5 And if any man will hurt them, fire proceedeth out of their mouth, and devoureth their enemies: and if any man will hurt them, he must in this manner be killed.<br>
6 These have power to shut heaven, that it rain not in the days of their prophecy: and have power over waters to turn them to blood, and to smite the earth with all plagues, as often as they will."<br><br>
So watch out for two mysterious prophets who may appear
by 2024-2030. See
<a href="KingJames1d.html">this page</a> for Bible Code matrices on the Two Witnesses which may indicate at least one of them is from the U.S..
The Two Witnesses: my painting shows the 2 witnesses, then a dragon sent by the beast kills them, then they are resurrected and rise into a UFO, which is what the cloud may be that they rise up into.
<br><br>
<img src="Painting2witnesses.jpg">
<br><br>
<br>
(12) Asteroid hitting earth. There is a possibility of an <a href="asteroid.html">asteroid</a> or comet hitting earth within a few years, since it is described in Revelation 8. This is why an asteroid defense is needed, which NASA could build if they were funded to do so.
<a href="KingJames11.html">These</a> King James Bible Code matrices indicate there could be an asteroid ocean hit in 2024-2030, the asteroid breaking up into 7 pieces in the atmosphere as it hits, so 7 impacts, and a giant tidal wave resulting that floods coastal cities. This could be the "seven thunders" of Revelation 10:3:<br>
"10:3 And cried with a loud voice, as when a lion roareth: and when he had cried, seven thunders uttered their voices.<br>
4 And when the seven thunders had uttered their voices, I was about to write: and I heard a voice from heaven saying unto me, Seal up those things which the seven thunders uttered, and write them not."<br><br>
Revelation 10: An angel appears on earth. Could this be a UFO with aliens in it landing in New York City, since it lands on an ocean-land borderline, and the United Nations is in New York City. And the "seven thunders had uttered their voices" could be about an alien weapon or alien broadcast device, broadcasting a message around the world. Like the movie "The Day the Earth stood still".
My painting of the angel of Revelation 10 - note the sun-like face, holding a scroll, a rainbow above him, standing on the land and the sea, and the 7 thunders as lightning bolts:
<br><br>
<img src="PaintingRev10.jpg">
<br><br>
Note that it is possible that this asteroid will break up into 7 pieces because it will be spotted ahead of time and broken up into pieces by an interceptor rocket with an atomic weapon in it, either launched by the U.S. or Russia.
Note that in February 2013 a meteorite landed in Russia with an atomic bomb size explosion. <br><br>
(13) Earthquakes and Tidal waves.
There could be steadily increasing earthquakes and volcanoes in 2024 - 2030.
There is also a volcano in the Canary Islands off Africa that could collapse in a few years, producing a giant tidal wave that could hit the coasts of Africa, Spain and Portugal, the U.S. East Coast, and the Carribean; see
<a href="KingJames8.html">this page</a> on King James Bible Code matrices on it. Another place there could be a giant tidal wave is from an undersea earthquake fault off the Northwest U.S., that could have a magnitude 9 earthquake causing a mega tsunami hitting Northern California, Oregon, Washington State, British Columbia, Alaska, Hawaii, and Japan. In June 2005 there were Northern California earthquakes near that under water fault zone, off Northern California and Oregon and Washington State, that brings up the possibility of a giant tidal wave occurring there, or the
<a href="KingJames8a.html">San Andreas fault</a> could slip in Southern California or Northern California, hitting hard Southern California and Los Angeles or San Francisco.
<br><br>
<A NAME="DISEASE"> </A>
<STRONG>The Astrology of Diseases related to Galaxies:</STRONG><br>
I will consider here three diseases that are a threat to
mankind: AIDS,
<a href="Ebola.html">Ebola</a>
, and Influenza. The virus that causes
<a href="AIDS.html">AIDS</a>, HIV, was discovered in 1983, so we will associate AIDS with
the number 83. The galaxy M83 is in the constellation
Hydra, which was a multi-headed serpent in mythology that
kept growing a new head, each time a head was cut off.
This sounds like AIDS, which keeps mutating to allow it to
get around any treatment or vaccine. The Hydra was
defeated by Hercules, by his nephew Iolaus burning each of
the mortal heads as Hercules cut them off, and burying the
immortal head under a stone. I wonder if this mythology
story could somehow be a clue on how to treat AIDS? Note
that the AIDS virus has 9213=111x83 bits of genetic
information, so again we see the number 83 again. <br>
Ebola, a lethal disease of Africa that kills in two weeks
of infection, had its virus discovered in 1976, so if we
associate galaxy M76 with it, we are near the constellation
Andromeda. Remember the movie "Andromeda Strain" about a
lethal disease that threatened humanity? That could be
Ebola if it mutates to an airborne form.<br>
Influenza was discovered in 1933. Galaxy M33 is in the
constellation Triangulum. That may imply we should look
for a triangle. The numbers 33, 76, and 83 do form a right
(90 degree) triangle with an angle of 66 degrees. <br><br>
<img src="T666.gif">
<br><br>
Since
666 is the number of the antichrist, this may imply that
these three diseases will threaten humanity when he
appears. In fact, ebola virus frequently twists itself
into
a shape that looks like a "6".<br>
These diseases may also relate to three animals used to
describe the Antichrist: he is like a leopard, has the
mouth of a lion, and the feet of a bear. Maybe Ebola
corresponds to the leopard, with its great speed; Ebola
kills in two weeks of infection.
Influenza could be the
lion; it causes coughing like a lion's roar. And AIDS
could be the bear; bears hibernate, like AIDS can do in
people, until it wakes up and kills them.<br>
<a href="BSE.html"> Mad Cow Disease (BSE) </a> infecting people's brains was announced in
March 1996 in England as the Comet Hyakutake passed by the
constellation (I mean constellation, not astrological sign)
Virgo the Virgin. I think that virgo the Virgin represents
Isis, the Egyptian Goddess portrayed with cow's horns,
giving us a "cow" connection. And Virgo may also represent
Europa, representing Europe, who rides a bull, again giving
us a "cow" connection. And Europa on a bull sounds like
the woman in revelation 17 named "Babylon" who rides the
beast of the antichrist (which may be Russia), I think the woman is Europe.
<br>
Another disease, Tuberculosis (TB) is becoming an increasingly bad worldwide epidemic, with drug resistant TB common. TB also is common in cattle.
The bacteria Mycobacterium was identified by Robert Koch as the cause of TB in 1882, so we will associate the number 82 and the Galaxy M82 with it, and Revelation 18:2 (King James Version):<br>
"18:2 And he cried mightily with a strong voice, saying, Babylon the great is fallen, is fallen, and is become the habitation of devils, and the hold of every foul spirit, and a cage of every unclean and hateful bird."<br><br>
Note that TB is spread by poor sanitation and hygiene, that we can relate to the"unclean" in the passage above; and Babylon was in Iraq. And galaxy M82 is in the Great Bear constellation Ursa Major, that we can relate to Revelation 13 where the Antichrist has the mouth of a lion, feet of a bear. And the bear is the symbol of
<a href="Russians.html">Russia</a>, where the Antichrist Putin is in power. Also, concerning the TB bacteria discovery in 1882, see
<a href="int666.html">this page</a> on how a cycle of events began in 1883.
<br>
Note: the first letters of SARS, Ebola, AIDS spells "sea", and the Antichrist (the beast) rises out of the sea (of world politics) in Revelation 13.
Also: the first letters of: Influenza, BSE, Ebola, AIDS, SARS, TB:<br>
I BEAST <br>
Also, SARS began in Guangdong Province, China, which is at geographic coordinates of 23 degrees North 112-115 East. Corresponding to 23 North would be the Bible's Psalm 23: (23:4, King James Version):<br> "Yea, though I walk through the valley of the shadow of death, I will fear no evil: for thou art with me"<br>
So this relates to this disease being the shadow of death. Also note that Hong Kong is near Guangdong Province in China, and Hong Kong is a former English colony: this may relate to the "mouth of a lion" of the Red Dragon Red China, the lion I related above to Influenza. Also note that on this site I relate the lion of the Antichrist to
<a href="Iraq.html">Iraq</a>, the lion being a symbol of Babylon, the ancient empire that was located in Iraq. So the war in Iraq in March 2003 may relate holographically to this "lion" disease SARS appearing then. This disease of SARS may be symbolic of the disease of Saddam Hussein that has existed in Iraq. Also, since SARS had its virus discovered in March 2003, then we can relate it to Galaxy M23, which is in the Constellation Sagittarius, Sagittarius being the half-man half-horse archer. This again would relate it to the Antichrist (who I think is Putin), since in Revelation 6:2 the Antichrist is a man on horseback with a bow and arrow. So SARS may indicate the rise of the Antichrist, the Satanic imitation of Christ, who is Vladimir Putin, to world prominence. And SARS coming out of China: the Antichrist gets his power from the dragon, indicating Putin will have an alliance with Red China, the Red Dragon. Also, corresponding to 23 for SARS (since SARS was discovered in 2003, and started near 23 North in China)would be Revelation 12:3 where the red dragon is seen in heaven. And the deadly COVID-19 Coronaviru appeared in China in 2019, so associate it with globular cluster Galaxy M19, which looks like the COVID-19 Coronavirus. <br><br>
A general pattern:<br><br>
Ebola: 76 (virus discovered in 1976)<br>
Rev. 17:6, the bloodthirsty woman (Ebola makes people bleed to death)<br>
Also in 1976: Chairman Mao dies in Red China, he was noted for being bloodthirsty, like this disease<br>
Galaxy M76 near Andromeda ("The Andromeda Strain")
<br><br>
AIDS: 83 (virus discovered in 1983)<br>
Rev. 18:3, the corrupt woman Babylon (Babylon being Iraq today)<br>
Also in 1983: Radicalism in the Arab World is increasing, after the assassination of Anwar Sadat in 1981; Osama was in Afghanistan in 1983<br>
Square root of 83 is 9.11, as in 9-11 (September 11)<br>
Galaxy M83 in Constellation Hydra (the Hydra being like the Terrorists, El Qaida, it keeps growing a new head each time you cut one off, as AIDS keeps evading a vaccine)
<br><br>
BSE (Mad Cow Disease): 86 (discovered in 1986)<br>
Rev. 18:6, the woman <br>
Galaxy M86 in Virgo the Virgin, here representing the woman, who is also Isis (who had cow horns)
<br><br>
Tuberculosis (TB): 82 (bacteria discovered in 1882)<br>
Rev. 18:2, the unclean city Babylon (Babylon was ancient Iraq)<br>
Galaxy M82 in the Great Bear; the Antichrist has the feet of a bear, and the bear is Russia, where the Antichrist Putin is in power
<br><br>
Influenza: 33 (virus discovered in 1933)<br>
Rev. 13:3, the beast (the Antichrist) rises out of the sea<br>
Galaxy M33 in Triangulum<br>
In 1918, world flu epidemic, as the Red Beast formed in Russia with the Russian Revolution (the beginning of the Antichrist's Evil Empire in Russia). And a bird flu virus infecting chickens and birds in Asia is a concern, since it could mutate and combine with swine flu and become a human pandemic.
The Swine Flu virus spreading in 2024 - 2030 could combine with Bird Flu, creating a more deadly virus.
<br><br>
SARS: 23 (virus discovered in 2003)<br>
Began near 23 degrees North in China<br>
Rev. 12:3, the Red Dragon seen in heaven<br>
Galaxy M23 in Sagittarius, the Archer horse/man, corresponding to the man on horseback with a bow in Revelation 6:2, the Antichrist
<br><br>
Coronavirus COVID-19: 19. Virus discovered in December 2019 in China, so Galaxy M19 in Constellation Ophiucus, the man holding a snake. Snake - the dragon in Revelation 13, the Coronavirus came from China, the dragon. Also snake - the Antichrist Putin. Galaxy M19 is a globular cluster that looks like a Coronavirus particle. This is the 4th horseman Death riding in 2024-2030. Note that it is believed this Coronavirus came from a Horseshoe Bat that is the carrier, and was being sold in a Chinese market. Note the name HorseShoe Bat - perhaps this is the horseshoe of the Fourth Horseman Death, a pale horse, in the Bible's Book of Revelation 6:8.
<br><br>
Generally, the prophecies discussed on this site may be changeable, if people will understand and listen to them and take appropriate action, such as building an asteroid defense. This may be a test for the human race: if people will understand that the disasters described in Revelation are occurring, then it may be possible to change the future and avoid these disasters.
<br><br>
In this web site I have tried to show how astrology, new age methods, religion, bible prophecy, the King James Bible Code, and mythology can be used in a combined way, to explain the world today and to predict the future. I try to find a middle way, between Christianity and New Age, because I think that is where the truth is. A middle way, as in Buddhism where a middle way between extremes is emphasized. And as in Hinduism, I have looked to Astrology and the stars for guidance. And the idea of a unifying religion is advocated here, as the Baha'i faith has a goal of unifying mankind; Baha'i is one of the most enlightened of world religions; begun in Iran, its world headquarters is in Haifa, Israel. <br>
The truth is found by following the Middle Way between religions, and that is the path I have tried to follow here. John 8:32: "And ye shall know the truth, and the truth shall make you free".
<br><br><br>
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<br>
<A NAME="LINKING"></A>
<br>
Please link to this web site! To help me spread my message to the world!<br> This site is:<br>
http://revelation13.net<br>
Title: "Revelation13.net: Astrology, Prophecies of the Future, Bible Prophecy and the Book of Revelation, the King James Bible Code"<br>
<br>
If you would like to use a banner in your link to my site, there are several at <a href="banners.html">this page</a>.
<br>
Thanks!
<br><br>
About the author of this site:<br> My name is T. Chase, and I live in the U.S.. I grew up in the U.S. as a Christian Protestant, and I am of English Anglo-Saxon ancestry, but today I would call myself a New Age Christian. This site is a one person effort by me, and the theories and opinions expressed on this site are my own. I have worked on my theories for 26 years, and I started a web site in 1998 to explain my theories to the world. <br><br>
And did I find any King James Bible Code matrices of interest for my own name and this web site? I tried as an experiment running a Bible Code search on my own name and the name of this web site, since it seems that so many things can be looked up in it.
Concerning this web site, this New Testament King James Bible Code matrix, at John 14:23 - Revelation 7:9, was found by searching for REVELATION THIRTEEN (since "Revelation13.net" is the name of this web site), my name TCHASE, and also note in this matrix there is: WEB (as in web site), AND WE HAVE SEEN, LOOKING FOR THAT BLESSED HOPE, THE SPIRIT OF THE WORLD, TO SPEAK UNTO THE PEOPLE, THEY TOOK KNOWLEDGE, BE REVEALED, THE TRUTH. I think these words describe what this web site Revelation13.net is about. John 8:32: "And ye shall know the truth, and the truth shall make you free".
<br> <br>
<img src="TChasea.jpg">
<br><br>
On psychic powers: I am an amateur psychic.
You can watch
<a href="psychic.html">on this page</a> videos where I demonstrate telekinesis, how I use my psychic telekinetic power to make clouds disappear at will.<br>
Years ago when I saw an extremely powerful psychic, it was said to me:<br>
"-- I would see you as the pied piper, the guide, the person that is probably more psychic than any of the psychics you have gone to in your life. <br>
-- As you go through life you are supposed to share wisdom. Your destiny is to teach, to lead, to be the guide. It is said that when the student is ready to teach you shall appear. That you move by Mars and Pluto, which is a sign of the upheaval."
<br>
Relating to my own psychic powers, I found this New Testament King James matrix at Mark 4:15 to Luke 21:29. The search words were: PSYCHIC, TCHASE, PROPHET, BEAST (since my web site is about the Beast, the Antichrist). Also, other phrases found in this matrix:<br>
- AND HE CAME BY THE SPIRIT<br>
- COME OUT OF THE MAN THOU UNCLEAN SPIRIT<br>
- HE SPAKE TO THEM A PARABLE<br>
- THUS SPAKE THERE CAME A CLOUD AND OVERSHADOWED THEM<br>
- BUT PERCEIVEST NOT THE BEAM THAT IS IN THINE OWN EYE (which sounds like psychic vision, a psychic beam)<br><br>
<img src="TchasePsychic4a.jpg">
<br><br>
-------------------------------------------------------<br>
<br>
<br>
Bible quotes are from the King James Version Bible.
<br>
<br>
Copyright 1998-2023 by T. Chase. All rights reserved.<br>
<br>
<br>
"I came, I saw, I built a web site."
<br><br>
Email T. Chase at: tchase800@aol.com
<br>
<br>
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Revelation13.net: Astrology, prophecies of the future for 2024 to 2030, Nostradamus, the Book of Revelation and Bible prophecy, the King James version English Bible Code, New Age geography, Psychokinesis Mind Control of clouds and wind
![](Ukraineflag2.jpg)
# *Revelation13.net*
####
Astrology, prophecies and predictions of the future for 2024 to 2030, Nostradamus, the Book of Revelation and Bible prophecy, the King James version English Bible code, New Age geography, Psychokinesis mind control of clouds and wind
*RUSSIAN PRESIDENT PUTIN IS THE ANTICHRIST 666 OF REVELATION 13 AND COULD START A NUCLEAR WAR SOON BECAUSE OF THE UKRAINE INVASION! Now that Ukraine is showing they can win this war, there is a great danger of Putin doing something drastic, such as launching nuclear weapons against Ukraine, NATO, and the West. Putin cannot stand losing the war and could launch atomic weapons or biological or chemical weapons against Ukraine and Europe. Putin is capable of anything. See below on why I say Putin is the Antichrist. So Putin is the most evil person on earth, The Beast 666, the Antichrist, in the Bible's Book of Revelation chapter 13. So Putin could set off nuclear weapons. And please aid Ukraine in any way you can in its battle with the evil one, the Antichrist Putin. Revelation 13 says about The Beast, also called The Antichrist: 13:7 "and it was given unto him to make war with the saints, and to overcome them".
(A master of war). 13:13 "And he doeth great wonders, so that he maketh fire come down from heaven on the earth in the sight of men." (Launching missiles with atomic weapons?) 13:18 "Here is wisdom. Let him that hath understanding count the number of the beast: for it is the number of a man: and his number is 666." The Antichrist is a Satanic imitation of Christ, Satan's man on earth. Christ was sent to save the world, the Antichrist was sent to destroy it.
Also consider this prophecy of Daniel:
Daniel 7, 8
"7:1 In the first year of Belshazzar king of Babylon Daniel had a dream and visions of his head upon his bed: then he wrote the dream, and told the sum of the matters.
3 And four great beasts came up from the sea, diverse one from another.
4 The first was like a lion, and had eagle's wings: I beheld till the wings thereof were plucked, and it was lifted up from the earth, and made stand upon the feet as a man, and a man's heart was given to it.
5 And behold another beast, a second, like to a bear, and it raised up itself on one side, and it had three ribs in the mouth of it between the teeth of it: and they said thus unto it, Arise, devour much flesh.
6 After this I beheld, and lo another, like a leopard, which had upon the back of it four wings of a fowl; the beast had also four heads; and dominion was given to it.
7 After this I saw in the night visions, and behold a fourth beast, dreadful and terrible, and strong exceedingly; and it had great iron teeth: it devoured and brake in pieces, and stamped the residue with the feet of it: and it was diverse from all the beasts that were before it; and it had ten horns.
8 I considered the horns, and, behold, there came up among them another little horn, before whom there were three of the first horns plucked up by the roots: and, behold, in this horn were eyes like the eyes of man, and a mouth speaking great things.
Note in this prophecy, which is about the Antichrist: the little horn: 3 of the horns, which are countries, are pulled out by the roots. The horns are the former satellites countries of Russia. So Ukraine may be the first invaded by Russia, and this is predicting that Russia will invade 2 others.
A quote relevant for our time:
Charles Dickens, A Tale of Two Cities:
" It was the best of times, it was the worst of times. It was the age of wisdom, it was the age of foolishness. It was the epoch of belief, it was the epoch of incredulity. It was the season of light, it was the season of darkness. It was the spring of hope, it was the winter of despair. "
April 8 2024. Solar eclipse across the U.S.. 3 solar eclipses across the U.S. in 2017, 2024, and 2045. This Solar Eclipse could indicate a bad period for the U.S. in 2024. Look at what happened to the U.S. in 2017 when there was a solar eclipse across the U.S., the U.S. entered a dark 4 year period in 2017 ending on January 20 2021, that saw the COVID-19 epidemic, and almost ended up in dictatorship in the U.S. on January 6 2021. A previous solar eclipse that crossed the U.S. on June 8 1918 saw the U.S. in World War 1 and the 1918 Flu Epidemic. Also at this time there may be a bright comet, Comet 12P/ Pons-Brooks, also called the "Devil Comet" because it appears to have 2 horns, certainly a very ominous sign. It will likely be seen during this solar eclipse.
The Nov. 2024 U.S. Election. I am a Democrat myself, so I hope that a Democrat is elected U.S. President. But my forecast is, looking at Astrology signs, I think that Nikki Haley could be elected U.S. President in November 2024. One sign of this is Pluto entering the Astrology Sign Aquarius on January 20 2024, implying that Nikki Haley could win the Republican New Hampshire Primary on January 23 2024, getting a boost for the next primaries. Note that on Presidential Inauguration Day January 20 2025, that will be Nikki Haley's 53rd birthday.
WE ARE SEEING A POSITIVE FORCE IN THIS COUNTRY IN 2021 WITH THE ELECTION VICTORY OF PRESIDENT BIDEN, CONGRATULATIONS PRESIDENT BIDEN AND BEST WISHES IN 2024.
Its great that President Biden was elected, this will result in a more positive and capable government for the United States compared to the previous 4 years. The January 6 2021 coup attempt could have ended democracy in the U.S. and turned the U.S. into a dictatorship. I think the force behind that coup attempt and the dark and disturbing things that have happened during 2017-2020 was the Antichrist Russian President
[Putin](Putin.html) controlling the previous U.S. President. If the U.S. had been turned into a dictatorship on January 6, then this could have put the U.S,. under Putin's control in his attempt to take over the world. I think Putin was using his hypnotic mind control powers to control the previous President, and Putin could have taken control over the U.S..
Note that the US system of government based on a 3 branches (President, Congress, Supreme Court) was designed by the founding fathers after the Roman Republic, which had a Senate and 2 Consuls that were the equivalent of the President and Vice President today. The Roman Republic ended becoming an Empire with an Emperor after Julius Caesar crossed the Rubicon River (the boundary of Italy) with his army, which was an act of insurrection, to declare Civil War on the Roman government, eventually defeating it and installing himself as
dictator. After Caesar Rome became an Empire with an Emperor who had total control, including evil tyrants such as Nero. So January 6 was the equivalent of Caesar crossing the Rubicon, an attempted insurrection that if it had been successful would have ended the United States Republic, and made it an Empire with an Emperor. The Romans had the idea that the 3 branches would give the Republic form of government stability. The U.S. Capitol insurrection on January 6 was a close call, and the U.S. Republic was saved by the Capitol Police, the Judicial Branch - the Courts, Vice President Pence, General Milley Chairman of the Joint Chiefs of Staff, and some in the Senate (Thank You, Mitt Romney and Ben Sasse), and some in the House of Representatives, especially Nancy Pelosi. Otherwise the U.S. could have an Emperor today, with the U.S. no longer a Republic.
A poem on the January 6 2021 Capitol Riot. Since the Capitol Riot was similar to the November 5 1605 Gunpowder Plot in London England, where there was an attempt to blow up Parliament and the King, I borrowed from a poem about it. The Gunpowder Plot poem begins:
"Remember, Remember, the fifth of November, the gunpowder treason and plot,
I know of no reason why the gunpowder treason should ever be forgot."
My poem:
Poem on the January 6 Capitol Riot
The 6th of January, a day of anarchy, mob violence treason and plot,
I know of no reason why the Capitol treason should ever be forgot.
The mob planned murder and violence against the Senate House and Mike Pence,
To stop the electoral voting and have a dictatorship commence.
But Vice President Pence surprised them,
and voted in President Biden,
and thanks to Vice President Pence the Constitution survived them.
The murderous mob did contrive,
to murder Democrats and leave few alive,
but the nation survived.
World Population reaches 8 billion:
Nov. 15 2022. World population reached 8 billion. Could relate to Revelation 8 and the opening of the seventh seal, could mean disasaters to soon come.
COVID-19:
I wonder if COVID-19 may have been created by aliens to prepare for an alien UFO invasion (described below) within a few years. COVID-19 may be modifying human DNA, viruses can find their way into human DNA, in preparation for alien takeover. Note Revelation 2:10 "be thou faithful unto death, and I will give thee a crown of life". Crown of Life - could that be as a result of DNA changes from the Coronavirus? Could it be modifying human DNA in some unknown way? Note there was a movie "Omicron" about aliens on earth in the 1960s, could this indicate that the Omicron COVID variant is somehow modifying human DNA in preparation for the aliens coming. Even though Omicron has less severe illness, it could be doing something to DNA. COVID-19 B.1.617.2 Delta variant, first seen in India, the deadliest variant yet, relate to Revelation 16:17 and Revelation 16:13 where "unclean spirits" (the virus) come out of the mouth of the dragon (China). And it has the P681R mutation, at the 681st position on the virus, that makes it spread faster, relate to Revelation 6:8 the Fourth Horseman of the Apocalypse Death. Also note Delta name - Delta triangle shape below the circular virus shape, a keyhole, relate to Revelation 1:18 "keys of hell and death", and Revelation 20:1 "key of the bottomless pit." COVID has a key in the spike protein that enables it to enter the cell.
[My videos on Youtube](http://youtube.com/revelation13net).
My painting on COVID-19
PROPHECIES AND PREDICTIONS OF THE FUTURE FOR 2024 - 2030. THE END TIMES EVENTS AND DISASTERS COULD OCCUR IN 2024 - 2030: THE ANTICHRIST PUTIN IS ATTEMPTING TO TAKE OVER THE WORLD. THE FOUR HORSEMEN OF THE APOCALYPSE RIDING IN 2024 -2030.
IN 2024 - 2030 THE FOUR [HORSEMEN](horsemen.html) OF THE APOCALYPSE RIDE: THE FIRST HORSEMAN THE ANTICHRIST 666 IS [PUTIN](Russians.html), THE SECOND HORSEMAN WAR (RUSSIA INVASION OF UKRAINE), THE FOURTH DEATH AS DISEASE EPIDEMIC SARS -LIKE COVID-19 CORONAVIRUS.
PUTIN THE THIRD ANTICHRIST OF THE NOSTRADAMUS PROPHECIES RISES TO POWER, THE FIRST TWO ANTICHRISTS WERE NAPOLEON AND HITLER.
3RD HORSEMAN ECONOMIC DISASTER.
SOON MAY COME
GIANT EARTHQUAKES, VOLCANOES, TSUNAMIS, GIANT SOLAR FLARES, MORE EPIDEMICS, WARS, MORE ASTEROIDS.
GIANT EARTHQUAKES AND VOLCANOES IN 2024-2030. WATCH OUT FOR GIANT VOLCANO ERUPTIONS AND EARTHQUAKES MAGNITUDE 7, 8 AND 9 AROUND THE WORLD IN 2024 - 2030.
[PUTIN](Putin.html) THE ANTICHRIST IN RUSSIA IS ATTEMPTING TO TAKE OVER THE WORLD, DESTROYING NATO. PUTIN USES HIS HYPNOTIC MIND CONTROL POWERS TO CONTROL OTHERS.
A METEOR HITTING IN RUSSIA MAY RELATE TO THE ANTICHRIST RISING TO POWER THERE AS PUTIN. AN ASTEROID DEFENSE IS NEEDED, MORE MAY HIT SOON. SEE
[THIS PAGE](asteroid.html).
ALIENS LANDING ON EARTH BY 2030 MAY BE PROPHESIED IN BIBLE PROPHECIES AND NOSTRADAMUS PROPHECIES, SEE THE CALENDAR AND NOSTRADAMUS PAGES ON IT. SEE THE [CALENDAR](calendar.html) PAGE ON THIS!
ALSO: RETURN OF CHRIST, BATTLE OF ARMAGEDDON, DEFEAT OF THE ANTICHRIST, POSSIBLE ALIEN UFO INVASION OF EARTH BY 2030!
There are different methods of predicting the future - such as psychics who have psychic predictions where they actually see the future, Nostradamus was this psychic type of prophet. For my predictions I use Astrology, combined with Bible prophecy including the Book of Revelation, Nostradamus prophecies, and numerical methods. And for me there may be a psychic element also in my predictions for 2024 to 2030.
This web site includes a discussion of the Book of Revelation, the last chapter of the Bible, which includes a description of a catastrophic sequence of events that some people believe are occurring now, and may occur in
[2024 - 2030](calendar.html).
These include earthquakes (such as the giant Indonesia earthquake and
[tidal wave](KingJames8b.html) in Dec. 2004 and the Japan magnitude 9 quake in 2011), wars, diseases
,
economic chaos, weather changes, and the rise to power of an evil dictator, called the Antichrist. He is identified by the number 666. Also in Revelation there are the
four horsemen of the Apocalypse -- the Antichrist, the conqueror, on a white horse; war, on a red horse; economic depression, on a black horse; and death rides a pale horse, and hell rides with him. The Four Horsemen of the Apocalypse are said to ride as the Antichrist rises to power. Also in Revelation, there are descriptions of angels, but the angel there can be an angel of death, carrying plagues. There is also a description in Revelation 8 of what appears to be an asteroid or comet hitting earth, destroying much of life on earth.
In Revelation Chapter 1: John, on the island of Patmos near Greece, sees Christ, as he is exiled on this island after
the death of Christ. Christ appears among 7 golden candlesticks. This may be the John who was Christ's disciple, or it could be
another John. Christ shows John visions of events to occur in the distant future,
during a period of time in the future called the End Times.
Christ refers to himself as "Alpha and Omega" to John in this vision, and since Alpha in
[Greek](Greek.html) represents the number 1, and Omega represents 800, this gives us a number of 801.
My painting shows Christ among the 7 golden candlesticks, with UFOs and an angel in the background. I believe there is a Christ - UFO connection, where Christ is an alien, refer to Revelation 19 on this, where Christ returns in the future leading a fleet of UFOs.
IN AUGUST 1999 WHEN PUTIN FIRST ROSE TO POWER IN RUSSIA, THERE WAS A RARE GRAND CROSS ASTROLOGY PATTERN OF PLANETS IN A CROSS SHAPE, AND A TOTAL SOLAR ECLIPSE OVER EUROPE, INDICATING THAT PUTIN IS THE EVIL ANTICHRIST OF REVELATION 13 WHOSE NUMBER IS 666.
Putin is attempting to destroy NATO and take over the world. Do not underestimate Putin - Putin has hypnosis mind control powers he can use to control people, hypnotizing them by staring at them, his eyes are said to be intense and hypnotizing. Others who could hypnotize people with their gaze were Rasputin and Hitler.
September 2017. The [Cassini](atomic.html) Saturn space probe crashed into Saturn/Satan. Cassini's connection to Putin: Putin first rose to power on August 9 1999.
Also then, the day of the Astrology Grand Cross in the sky: August 18 1999, was the day after Cassini, carrying Plutonium, passed close to earth.
And 1999 has 666 upside-down, 666 being the number of the Antichrist in Revelation 13.
This August 1999 Grand Cross, which is one of the most amazing astrological alignments ever seen in history, consisted of: the Sun, Venus, and Mercury in the sign of Leo, Mars and the Moon in Scorpio with Pluto close by in Sagittarius, Saturn and Jupiter in Taurus, and Neptune and Uranus in Aquarius. If Scorpio is considered to be the Eagle, and Aquarius the man, then we have the four beasts seen in Revelation 4 that sit at the throne in heaven, that have the faces of an eagle, a man, a lion, and a calf. This seems to indicate an important time for mankind; I think it may also relate to the rise to power of the Antichrist in year 2000 as Russian President Putin, especially since there was a cross pattern. Also, note that August 13, 1999 was Friday the 13th, said to be an unlucky day. Also note that August 9, 1999, was the 30th anniversary of the Charles Manson group's murder of Sharon Tate and others in Los Angeles, significant because of the Charles Manson group's Satanic-like cult. Also: August 13 1999 was the significant future date on the Aztec Sun calendar from Mexico of 500 years ago, and August 13 1999 was predicted by the Aztecs to be an important day of change for mankind, that would change the world, as described in the book: "Day of Destiny, Where will you be on August 13 1999?", by John Mini, published 1998 by Trans-Hyperborean Institute of Science.
Considering again Cassini going to Saturn: as for the planet Saturn, possibly Saturn represents "Satan"-- the Antichrist is said to be a Satanic imitation of Christ, actually the son of Satan. So the Cassini probe journey to Saturn actually may be the journey of mankind to "Satan". Also note that in
[Greek](Greek.html), where each letter is also a number, "Titan" totals 666, another indication of the Cassini landing on Titan being connected with the Antichrist. Note that Titan (representing the Antichrist?) revolves around Saturn/Satan. So Cassini crashing into Saturn on Sept. 15 2017 could relate to who was the U.S. President then.*
*What's New:*
I am updating the
[calendar](calendar.html) page and other pages for 2024, and adding more astrology charts.
Why do I say that Putin is the Antichrist of Book of Revelation chapter 13? There are many reasons why I am sure that Putin is the evil one who will bring about World War 3, that I discuss on the pages on [Putin](Putin.html) and [Russia](Russians.html). The biggest reason is that when Putin first rose to power there was an unusual Astrology pattern that also relates to a [Nostradamus](Nostradamus.html) prophecy about the Antichrist. Let us consider the
Grand Cross Astrology pattern of August 1999. On August 18, 1999,
there was an unusual alignment of planets in a Grand Cross shape, possibly the most
unusual Astrological alignment seen in the last two thousand years. And one week
before, on August 11, 1999, there was a solar eclipse seen over Europe. The Grand
Cross, which is one of the most amazing astrological alignments ever seen in history,
consisted of: the Sun, Venus, and Mercury in the sign of Leo, Mars and the Moon in
Scorpio with Pluto close by in Sagittarius, Saturn and Jupiter in Taurus, and Neptune
and Uranus in Aquarius. The cross is a bent cross, relating it to the Antichrist, as the true cross relates to Christ.
Concerning the solar eclipse over Europe on August 11, there is a prophecy by
Nostradamus that is of interest.
The Prophecies of Nostradamus predicted 3 Antichrists: the first was Napoleon, the second was Hitler, and the third I think is Russian President Putin.
Some of the Nostradamus prophecies do have dates, including
Century 10, Number 72:
"In the year 1999, in the seventh month,
from the sky there comes a great king of terror,
to bring back the great king of the Mongols,
Mars rules triumphantly, before and after"
Concerning this prophecy by Nostradamus, it is interesting that the solar eclipse
passed over France on August 11,1999, and on August 17, 1999 the Cassini spacecraft
with its nuclear fuel passed within a thousand miles of earth's surface, within a day
of the Grand Cross pattern. I think the significance of Cassini passing by earth within
a day of the Grand Cross pattern is that Cassini may be a hologram, a symbolic
parallel event, related to the rise to power of the Antichrist in Russia as Vladimir Putin, President of Russia.
Note that the Cassini spacecraft reached Saturn in July 2004, and landed a probe on Saturn's moon Titan in Jan. 2005. "Titan" in Greek totals 666 (the number of the Antichrist), where in
[Greek](Greek.html) each letter is also a number, and Greek is the language of the Book of Revelation and the New Testament.
Note that Russian
President Putin began his rise to power in Russia in August 1999, at the time of the Grand Cross Astrology pattern and solar eclipse over Europe, becoming Prime Minister for Yeltsin (second-in-command in
Russia) on August 9, 1999. On December 31, 1999, Putin became Russia's President. And Mars is war - war will occur when Putin is in power. "King of the Mongols" - that Putin will be a tyrant rising to power in Asia.
Charles Manson has been in the news in recent years, he is an alleged mass murderer in prison for life in California. This may be significant in our discussion of the Antichrist Putin. Note that the Antichrist in Revelation 13 has the number of man, and 666. Man-son. And note that the Manson murders of Sharon Tate and others in LA California was on August 9, 1969. That was exactly 30 years before the Antichrist Putin became Prime Minister of Russia on August 9 1999, at the time of an August 11 1999 solar eclipse over Europe, and the August 18 1999 Grand Cross Astrology pattern of planets in a cross shape. And actress Sharon Tate who was murdered was the wife of Roman Polanski, who in 1968 had made a movie called "Rosemary's Baby" about the child of Satan. Also note that Charles Manson's cult lived in Death Valley in California, and Charles Manson included Book of Revelation prophecies in twisted form in his twisted philosophy.
April 25, 2014. The Prime Minister of Ukraine said he thinks Putin wants to start World War 3. I think he is correct, I think Putin could start World War 3 with a missile attack on the West in the near future.
At Armageddon, World War 3, of Revelation 16, there is a great nuclear war, I think started by Putin or China. The Antichrist is defeated by the returned Christ, as described in Revelation 19. The returned Christ (possibly returning by 2030) with his armies (of aliens and UFOs) may actually be an [invasion](alieninvasion.html) of earth by aliens in UFOs, read Revelation 19 and it sounds like that. My painting of Christ leading a UFO alien invasion of Earth:
A reason for invading earth may be that the aliens are concerned about global warming and earth's environment, refer to Revelation 11:18 "shouldest destroy them which destroy the earth".
And the New Jerusalem of Revelation 21 could be a giant alien city that comes down to earth after the alien invasion. Revelation 21 and 22 seem to be describing the reorganizing of earth by aliens. So Christ would be lead alien. And Nostradamus prophecies also prophesied alien invasion of earth and human genetics DNA modified for immortality, see
[this page](Nostradamus.html).
(These paintings are by T. Chase. .)
(Paintings by T. Chase - Christ returns on a UFO as described in Revelation 19. And the New Jerusalem is brought down to earth.).
(The New Jerusalem is brought to earth by UFOs).
Years 2024-2030 could see the End Times events with the rise and defeat of the Antichrist, from my [calendar](calendar.html) page:
And see the
[calendar](calendar.html) pages on how a triangle pattern appeared on the sun on March 14 2012 when there was a 999 (666 upside-down) grand trine triangle astrology pattern, after the March 4 election of
[Putin](Putin.html) the Antichrist in [Russia](Russians.html). Does Putin the Antichrist 666 have power over the sun? Revelation 13:13 (King James version) on the Antichrist: "And he doeth great wonders, so that he maketh fire come down from heaven on the earth in the sight of men." Solar flares? Putin was reelected as Russian President on March 4 2012, and 2 days later March 6 the sun sent a solar flare towards earth. See [this page](Russians.html) on Putin's connection to Ra the Egyptian sun deity. And the Cold War appears to be returning, with Putin returned as Russian President, a Russian General having made threats in May 2012 of a nuclear strike against NATO ABM Anti Ballistic Missile sites being deployed in Eastern Europe. Revelation 13:13 (King James version): "And he doeth great wonders, so that he maketh fire come down from heaven on the earth in the sight of men." So could Revelation 13:13 be about Putin (or North Korea) launching a nuclear missile strike on Europe or the U.S., starting World War 3 in the future? Or could this be about Putin causing giant solar flares to hit the earth?
Note: One reason why a Southern California large earthquake has not occurred is because there may be an alien UFO base off the coast of Los Angeles (LA), and the aliens may be preventing a Southern California San Andreas Fault quake which could damage their underwater base. They may be slowly releasing the earth stress to prevent a quake there. A lot of UFOs have been seen entering and leaving the deep water off the coast of L.A., so its very likely they have an underwater base there. Therefore it is unlikely there will be a major Southern California Quake in future years. Controlling earthquakes is easy for these aliens.
In this site Revelation13.net, my method of prophecy combines
Astrology and other New Age Schools, mythology,
religion, the prophecies of
[Nostradamus](Nostradamus.html), Bible Code in the [King James](KingJames.html) Bible, Bible prophecy, and
[numerical analysis](int666.html). In particular, the
[Book of Revelation](Apocalypse.html) of the King James Bible is discussed. This web site is huge, you can spend days reading it. The
emphasis of this web site is on predicting the future for years
[2024 - 2030](calendar.html). There could be ominous events possibly occurring in 2024 - 2030: quakes, volcanoes, Flu or SARS -like Coronavirus (2020) epidemic, and wars.
This is a new
holistic method of prophecy I have developed. Also on this web site are videos on
[Psychokinesis](psychic.html), where I demonstrate using Psychic Energy to control the weather, clouds and wind, by psychic ESP mind over matter power, telekinesis, making clouds grow or disappear and controlling the wind.
I will give
a detailed description of my theories in this web site.
Also
discussed
here:
[economic](economy.html) predictions and the Stock Market,
predictions of world events for
this year and future years.
Note that Revelation 6:8 is about the Fourth Horseman, Death, so will Death ride in 2024-2030 as a worldwide epidemic, likely as the COVID-19 Coronavirus?
Above: my painting of the Fourth Horseman, and Hell also riding with him.
Also, the Astrological events of
[August 1999](atomic.html) (a solar eclipse seen in Europe and a rare alignment of planets in a cross shape) is discussed.
Possible Antichrist sighting: I think the Antichrist is the Russian President elected in March 2000, Vlad
[Putin](Russians.html), and the Red Dragon that Putin the Antichrist will be allied with is
[China](China.html), as well as Iran. And the planetary alignment of
[5/5/2000](polar.html) with the sun and planets on one side of the earth is discussed, note that Vladimir Putin was inaugurated as President of Russia 2 days later on May 7, 2000.
And on November 4 2003 there was the largest solar flare ever seen, when Putin was in Rome, and on Nov. 8 there was a lunar eclipse and a grand sextile hexagon shaped astrology pattern, again indicating Putin is the Antichrist; apparently Putin visiting Rome, which is connected with the Antichrist in Bible prophecy, resulted in a tremendous Satanic force that resulted in the giant solar flare on Nov. 4 2003, see
[this page](Putin.html). And the possibility of a doomsday
[asteroid](asteroid.html) or comet collision with earth is discussed, note that in 2002 there were several asteroid near-misses with earth; and a King James Bible Code matrix may predict an
[asteroid hit in the ocean](KingJames11.html) within a few years, causing a giant tidal wave. A suggestion: a great economic stimulus project would be to build an asteroid defense for earth, for a few billion $ NASA could build an asteroid defense using interceptor rockets, and this would create jobs in the U.S..
Also, on this web site, other prophet's
[prophecies](prophecies.html) are discussed, other Bible
[prophecies](prophecy.html).
And watch my
[videos](http://www.youtube.com/Revelation13net)
on the subjects discussed here, including the King James version English Bible Code, prophecies of the future, Nostradamus, and other subjects.
This web site used Codefinder Millennium Edition Bible Code software.
Generally, on this web site astrology, new age methods, numerical analysis, religion, and mythology are combined to explain the world today, and to predict the future.
**To go to the section:**
*Predictions for the near future:*
[Predictions](#PRED) of world events
[Calendar](calendar.html) of dates, past and future
[Economy](economy.html) and Stock Market
[Alien](alieninvasion.html) invasion soon?
*Number and time patterns:*
[666](int666.html) Day Intervals and other time cycles
[The Julian](Julian.html) Day Count
[Number patterns](Greek.html) in Greek, the original language of the Bible's Book of Revelation and the New Testament
[Number patterns](Hebrew.html) in Hebrew, the original language of the Old Testament
[ASCII](ASCII.html) number patterns
*Astronomy and Earth Science:*
[The Southern Cross](supernova.html) Effect and the 1987 supernova
[Eta Carinae](Carinae.html), the giant Southern Hemisphere star, could it become a giant supernova soon?
[Comet Hale-Bopp](comets.html), Comet Hyakutake, and could there be another bright [comet](comet.html) soon?
[Prophecy patterns](astronomy.html) in Astronomy
[Could a comet](asteroid.html) or asteroid hit earth?
[Could a giant solar flare](sun.html) scorch the earth?
[Predictions on earthquakes](earthquake.html), volcanoes, tsunami tidal waves
*Diseases:*
[Astrology/ New Age discussion of diseases:](#DISEASE)
[Ebola](Ebola.html),
[Flu](Flu.html),
[AIDS](AIDS.html), Mad Cow Disease
[SARS and 2020 COVID-19 Coronavirus](SARS.html) , [Smallpox](Smallpox.html)
[Foot-and-mouth disease](foot-and-mouth.html) in sheep, cattle, and pigs and England, "the slaying of the lamb"
*People:*
[Princess Diana](Diana.html) and Prince Charles, and Prince Harry and Meghan Markle
[Pope](KingJames2b.html) John Paul II and Pope Benedict XVI
*The world*:
[New Age geography - country shapes and land area related to Revelation](geography.html)
[Patterns](geographic.html) of geographic coordinates
[Patterns](population.html) of world and country populations
[Russia](Russians.html), Feet of a Bear: is Russian President Putin the Antichrist?
[Russian](Putin.html) President Putin more on why he may be the Antichrist.
[Hitler](Hitler.html), predecessor to the Antichrist
[China](China.html), the Dragon: And the dragon gave him his power, and his seat, and great authority
[Iraq](Iraq.html)
[The 9/11/2001](war.html) attack on the U.S.
[More on](Osama.html)Terrorism, and Major Terrorists
[Europe](Europe.html),
[Israel](Israel.html)
[Places](places.html) to visit: cathedrals, churches, New Age sites, other places of interest
*Ghost or spirit photos at:*
[Salem MA](Salem.html)
[Gettysburg PA](Gettysburg.html)
*Astrology alignments:*
[August 1999 Grand Cross](atomic.html) Astrology alignment and the Cassini Spacecraft fly-by near Earth, and the Rise of the Antichrist Putin; King James version Bible Code on it; and 6-6-6 Degree Astrology patterns
[May 5 2000](polar.html) planetary alignment, did it announce the rise of the Antichrist in Russia?
[March 14 2012](triangleonsun.html) triangle astrology pattern when a triangle was seen on the sun, Antichrist related
[December 21 2012](December212012.html) Mayan calendar date
[Astrology charts](astrologycharts.html)
*Other subjects:*
[The Shroud of Turin](shroud.html)
[Virgin Mary sightings](Mary.html), including at Milton Hospital in Massachusetts and Clearwater Florida
[Patterns](atom.html) in Chemical Elements
[A discussion of recent movies](movie.html), and prophecy
*Prophecies: Bible and other:*
[Description of sections](Apocalypse.html) of the Book of Revelation
[The Four Horsemen](horsemen.html) of the Apocalypse
[Other Bible prophecies](prophecy.html)
[The Prophecies of Nostradamus](Nostradamus.html), do they indicate the Antichrist is Russian President Putin?
[Prophecies of others](prophecies.html), from the past
*Pages on the King James version English Bible code, with matrices I generated myself and analysis:*
[Page 1](KingJames.html): The First Page Introduction on the King James Bible Code
[Page 1a](KingJames1a.html): Russia and President Putin; the U.S.; Osama bin Laden and Al Qaida
[Page 1c](KingJames1c.html): Jesus Christ as Messiah
[Page 1d](KingJames1d.html): The Two Witnesses
[Page 1e](KingJames1e.html): Russia invading Ukraine in 2014 and 2022
[Page 1f](KingJames1f.html): North Korea and China
[Part 1i](KingJames1i.html): United States Civil War of 1860 - 1865
[Part 1j](KingJames1j.html): The New Russians Submarines and Missiles to threaten NATO and the U.S.
[Part 1k](KingJames1k.html): Brexit UK leaving the EU
[Part 1l](KingJames1l.html): Japan and the Honjo Masamune, the missing Samurai Sword
[Page 2](KingJames2.html): Princess Diana
[Page 2b](KingJames2b.html): Pope John Paul II, Pope Benedict XVI, Pope Francis
[Page 2d](KingJames2d.html): The 2005 Election in Germany and Angela Merkel
[Page 2g](KingJames2g.html): The JonBenet Ramsey Unsolved Murder Case
[Page2i](KingJames2i.html):
Percy Fawcett who went missing in the Amazon jungle in the 1920s
[Page 3d](KingJames3d.html): Iran and Nuclear Weapons
[Page 4](KingJames4.html): The U.S. Presidential Elections in 2004 and 2000
[Page 4a](KingJames4a.html): President Obama reelected in 2012
[Page 4b](KingJames4b.html): On Joe Biden and Kamala Harris, elected President and Vice President in November 2020
[Page 4c](KingJames4c.html): Vice President Mike Pence
[Page 6](KingJames6.html): Cold Fusion, can it generate nuclear power? Can it power Time Travel?
[Page 6a](KingJames6a.html): String Theory, M-Theory, other dimensions, and a Unified Theory of Everything.
[Part 6c](KingJames6c.html): Increased Earthquakes and Volcanos around the World
[Page 7](KingJames7.html): A Nuclear Fission reactor in Earth's Core?
[Page 8](KingJames8.html): Could a volcano in the Canary Islands result in a giant tidal wave hitting the U.S. and Europe? And could Yellowstone in Wyoming explode as a supervolcano?
[Page 8a](KingJames8a.html): Could a giant magnitude 8 earthquake shake the San Andreas Fault in California, in the near future? Or a giant tidal wave hit California?
[Page 8b](KingJames8b.html): The Magnitude 9 Earthquake and Tidal Wave off Indonesia in December 2004.
[Page 8c](KingJames8c.html): A Giant Earthquake on the New Madrid Fault Line in the Central U.S.?
[Page 8d](KingJames8d.html): Hurricane Katrina hits Florida, Louisiana, and Mississippi in 2005
[Page 8e](KingJames8e.html): Earthquake in Japan
[Page 8f](KingJames8f.html): Will Mount Rainier in Washington state erupt soon? Will the Hekla Volcano or Katla Volcano in Iceland erupt soon?
[Page 9a](KingJames9a.html): How will the stock market and world economy do?
[Page 10](KingJames10.html):
Ebola Disease, the deadly virus of Africa; could it cause a worldwide plague? Also, AIDS and HIV, Mad Cow Disease (BSE), Influenza (bird flu or swine flu), COVID-19.
[Page 10a](KingJames10a.html): Autism in children
[Page 10b](KingJames10b.html): Cancer
[Page 10c](KingJames10c.html): Alzheimer's Disease
[Page 10d](KingJames10d.html): on the Aging Gene TOR, and DNA Telomeres and Aging
[Page 11](KingJames11.html): Could an
asteroid or comet hit earth soon ( an ocean impact, 7 pieces, 7 hits, tidal wave), causing an Extinction Level Event (ELE)?
[Page 11a](KingJames11a.html): Gamma Ray Bursts (GRB)
[Page 12](KingJames12.html): Two Southern Hemisphere stars that I relate to prophecies: the 1987 supernova and the giant star Eta Carinae.
[Page 12a](KingJames12a.html): Is there Life outside Earth in our Solar System - on Mars, Europa, or Titan? Are Flying Saucers and Aliens for real? Men in Black. W56 UFOs and Aliens. The Nazca Lines in Peru, a sign of Alien Visitors? President Obama and Aliens. George Adamski who saw Aliens and UFOs in the 1950s.
[Page 13](KingJames13.html): A Jean Dixon prophecy
[Page 14](KingJames14.html): Nostradamus prophecies are interpreted by the Bible Code
[Page 14a](KingJames14a.html): John Titor and his story of time travel and prophecies. He said he was from year 2036.
[Part 14b](KingJames14b.html): On the Mayan Calendar Date December 21 2012, and the Crystal Skulls
[Page 15](KingJames15.html): The Bible Code related to "The Da Vinci Code" (the book by Dan Brown), the Knights Templar, and the Mary Magdalene mystery.
[Page 15a](KingJames15a.html): Crop Circles and the Bible Code, and the rise of the Antichrist.
[Page 16](KingJames16.html): The Voynich Manuscript; can the Bible Code decode this strange document?
[Page 16a](KingJames16a.html): The Indus Script, a language from ancient India that is still not deciphered
[Page 16b](KingJames16b.html): Megaliths and Stonehenge, Gobekli Tepe
[Page 16c](KingJames16c.html): The undeciphered language Linear A of Crete, and the Etruscans of Italy, and Easter Island and Aliens
[Page 16d](KingJames16d.html): The Legend of the Continent of Atlantis
[Page 16e](KingJames16e.html): Oak Island in Canada where there may be buried treasure
[Page 17](KingJames17.html): Human Evolution and Neanderthal Man, and is the Human Brain a Quantum Computer?
[Page 17a](KingJames17a.html): Strange Creatures: Bigfoot, the Abominable Snowman, the Loch Ness Sea Monster
[Page 17b](KingJames17b.html): Psychic ESP Telekinesis Mind over Matter Power
[Page 17c](KingJames17c.html): Zombies
[Page 17d](KingJames17d.html): The Rapture
[Page 17e](KingJames17e.html): Reincarnation and Past Lives
[Page 17f](KingJames17f.html): 3 Psychics - Edgar Cayce, Jeane Dixon, Leslie Flint
[Page 18](KingJames18.html): Doctor Who the Science Fiction TV Series
[Page 19](KingJames19.html) : on Famous Artists: Da Vinci, Van Gogh, Vermeer
Videos:
Watch my
[videos](http://www.youtube.com/Revelation13net)
on subjects discussed on this web site: the King James version English Bible Code, Nostradamus prophecies, AIDS disease, John Titor the Time Traveler, Cold Fusion Nuclear Power, Bible prophecy, prophecies of the future for the next 10 years, New Age Geography, and many other subjects.
*Books and links:*
[Recommended books](books.html) and web sites
*Psychic and Dreams:*
[Dream Log:](dreams.html) Dreams I have had.
[Psychic](psychic.html) Psychokinesis Powers of Weather Control are demonstrated in videos I made, making clouds grow and disappear and controlling the wind.
[Page 2](psychic1.html) on Psychokinesis Weather Control
[Page 3](psychic2.html) on Psychokinesis Weather Control
[Page 4](psychic3.html) on Psychokinesis Weather Control
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Email T. Chase at: tchase800@aol.com
**Predictions for 2024 - 2030:**
(1)1998=666x3, and 1999 has 666 upside down, and 666 is the number of the Antichrist
(also called The Beast) in
Revelation 13, I believe these numbers are connected with his appearance in year 2000 (as Russia's President Putin), and there will be a powerful satanic influence in the world (related to Putin) in 2024 - 2030, that relates to the rise of the Antichrist Putin.
Revelation is the last chapter of the Bible, and includes a
series of prophecies of catastrophic events-- wars, earthquakes, diseases,
[economic](economy.html) chaos, and the arrival of the
Antichrist. Angels are also mentioned in Revelation, such as an angel from the East in Revelation 7, another Angel in Revelation 10.
As described in
the prophecies of Revelation, the
Antichrist is the son of Satan, a Satanic imitation of
Christ. The Antichrist will be assisted
by the False Prophet, who is the Second
Beast of Revelation 13. The False Prophet is said to work
apparent miracles, including "bringing fire down from
heaven". The Antichrist is described as having the mouth of a lion, feet of a bear, and gets his power from the dragon: the bear is Russia, the dragon is Red China and also Satan, and the mouth of a lion I think is Hong Kong, the former British colony that is now part of China. This indicates a Russia-Red China military alliance. A second meaning of the lion is
[Iran](KingJames3d.html), where before the Islamic Revolution Iran had a Lion on its flag, indicating a Russia-China-Iran military alliance, with Iran supplying military drones to Russia. The "mouth of a lion" could be Iran.
"The little horn" is a name for the Antichrist from the Book of Daniel (note Putin's small size), so St. Petersburg Russia is where this little horn of the red beast has grown.
Alternative lion/bear/dragon: Russia-Iran is the bear-lion beast that sits on the dragon China, and gets its economic power from China.
Also note Revelation 16:12, where the River Euphrates in Iraq is dried up by the sixth angel, so that an army from China ("the King of the East") can cross to the Battle of Armageddon, World War 3. Note China's increasingly strong military, now second only to the U.S.. World War 3 could be started by China. See my painting on this:
And in this painting by me from Revelation 16 are shown 3 angels who turn rivers and the sea to blood, and have the sun scorch the earth with fire.
And in this painting by me, referring to Revelation 8 and 15, are shown 7 angels, who result in lightning and there is a sea of fire and glass.
(2) A key sign in 1998-99 that could relate to the arrival of
the Antichrist was on April 23, 1998, (and also Feb. 23, 1999) when
the planet Venus
approached close to Jupiter in the sky. Jupiter relates to
the Antichrist, because Jupiter and Thor (the Scandinavian
equivalent) are said to control lightning and thunder, and
the Antichrist is said to bring "fire down from heaven",
which sounds like lightning. Venus having a close conjunction to
Jupiter could mean Jupiter is "lit" by the close approach
of Venus. There was a similar but much closer approach of
Venus to Jupiter on June 17, 2 B.C., near the time of birth
of Christ; the 2 planets actually appeared to merge in the
sky. This could have accounted for the Star of Bethlehem
legend; the 3 wise men were Astrologers, and such an
unusual planetary conjunction would have had great
significance for them. So, these similar conjunctions in
1998 and 1999, and on February 1 2008 a close approach of Venus and Jupiter to within .5 degree, could mean the Antichrist rose to power in 2000 and I think he is Russian President Putin. And note that on May 17, 2000 Venus and Jupiter also had a very close conjunction, only 4' apart, but were too close to the morning sun to be seen. And note that on Nov. 4, 2004, Venus passed within .6 degree of Jupiter. Also on July 1 2015 there was a close conjunction in the sky of Venus and Jupiter, and on on October 28 2015 a close conjunction of Venus, Jupiter, and Mars.
Also of interest was the
[5/5/2000](polar.html)
grouping of the planets on one side of the earth: the 5/5/2000 alignment may be just another sign of the rise of the Antichrist, note that President Putin was inaugurated as President of Russia 2 days later on May 7, 2000.
Possibly the Antichrist was elected as Russian President Putin in the spring of 2000. See the
[Russia](Russians.html) section for a discussion of this and some interesting facts on President Vladimir Putin. Also indicating
[Putin](Putin.html) is the Antichrist: Putin visited Rome on November 4 2003, on the day there was the largest solar eruption from the sun in history. And November 8 2003, during a lunar eclipse, there was a hexagon astrology pattern (6 sides, as in 666) that I relate to the Antichrist Putin, also on the
[Putin](Putin.html) page.
Another way Putin will come to world power as the Antichrist is by controlling the world's Natural Gas reserves, Russia having the world's largest Natural Gas reserves.
But I think an event frequently discussed in Biblical Prophecy called "The Rapture" will not occur, because this is a misinterpretation of Biblical prophecy by innumerable writers and preachers. Supposedly "The Rapture" would occur during or just before the rule of the Antichrist, and would be an instantaneous disappearance of millions of Christians around the world, leaving other people behind, and it is described as a joyous event where they will all go to heaven together. I think this will not happen, because these writers and preachers are not correctly interpreting Bible prophecy. I think we are in the End Times, but the Rapture will not occur.
Or The Rapture could be related to aliens, possibly a mass alien abduction of millions of people, possibly related to an alien invasion of earth that could occur within a few years, see the calendar page on it.
(3) Significant dates, see the
[calendar](calendar.html) section for more:
(4) [Economic recession](economy.html) or depression
in the world economy in 2024-2027, the 3rd horseman economic disaster riding;
I believe that 4 of the Planets
correspond to the [Four Horsemen of the Apocalypse](horsemen.html)
in
Revelation; Jupiter is the Antichrist, Mars is War, Saturn
is Economic Depression, and Pluto is Death (and Hell rides
with Death, Pluto has a single moon Charon, which like
Pluto has a mythology connected with the Land of the Dead.)
Saturn I would relate to economic depression, because in
Greek / Roman / Etruscan mythology, Saturn was associated with
agriculture as well as weights and measures and coins. So, there could
be worsening world economic problems in 2024-2030, caused by the Coronavirus epidemic.
(5) War. War could be a worsening problem in 2024-2030 China could start a war by invading Taiwan. Russia could continue invading Ukraine and possibly other former Soviet Union countries to incorporate into Russia and start World War 3 by launching missiles. General war in Europe or World War 3 is possible. In the Middle East also.
Russia has threatened a missile strike on NATO and the U.S., and North Korea has threatened to launch a missile strike on the U.S..
So Russia or China could start a nuclear war.
There is also concern over the Second Horseman War riding in 2024-2030.
(6) The Cassini spacecraft passed by earth on August 17, 1999, on the same day as a [Grand Cross Astrology pattern](atomic.html),
the most unusual Astrology pattern of the last 2000 years. The planets aligned in a cross shape. And that was a week after a solar eclipse over Europe. Note that Vladimir Putin became Prime Minister in Russia in August 1999, this Grand Cross and eclipse may relate to Putin's rise to power as the Antichrist, and the Cassini probe to Saturn/Satan may be a holographic parallel to Putin's rise to becoming Antichrist. Since the Cassini spacecraft landed a probe on Titan in Jan. 2005, this could be related to the rise of the Antichrist (Putin), note that Titan in Greek (the language of the Book of Revelation) totals 666, see
[this page](Greek.html) on Greek.
(7) Diseases. Disease epidemics in 2024-2030, with the Coronavirus pandemic or Flu. The Fourth Horseman of the Apocalypse Death riding.
(8) The Southern Cross effect. In 1987 there was a
Supernova in the Southern Hemisphere sky, "igniting"
astrologically the positive influence of a nearby
Constellation, the Southern Cross. This began a positive
sequence of events in the Southern Hemisphere, with
Democracy coming to South America after that, and positive
change to South Africa.
But the
Northern Hemisphere could see problems, related to the
economy, war, natural disasters, diseases; the Four Horsemen riding in 2024- 2030. In 1993 there was a Supernova
in the Northern Hemisphere Great Bear Constellation, and
since Draco the Dragon is a constellation close to it, and
the Dragon is Satan in Biblical symbolism, this began a
negative influence over the Northern Hemisphere, which will
likely continue. So the Northern Hemisphere will likely
see problems with earthquakes, volcanoes, diseases, wars,
weather changes, economic problems, the rise of the Antichrist in Russia, terrorist attacks.
(9)Comets. We have seen bright
[comets](comets.html)
in 1996 and 1997,
and I think there could be another bright comet in 2024-2030.
As Comet
Hale-Bopp peaked in April 1997, there was a fire in April
1997 in the Cathedral holding the Shroud of Turin in Italy,
but the
[Shroud](shroud.html)
fortunately escaped damage, due to the
bravery of a Turin firefighter. The Shroud of Turin is
believed by many Christians to be the burial cloth of
Christ. Recent carbon tests seemed to indicate it was a
fake, but those tests are considered by many people to be
invalid because: (1) there was bacteria growth on the cloth
that invalidated the measurements (2) a previous fire in
1532 resulted in carbon deposits on the cloth that
invalidated the recent carbon tests. So, the cloth could
be the real burial cloth of Christ, bearing his image on
it. What is interesting, is that at the time of the
previous shroud fire, there were three bright comets in 3
years, in 1531-1533. And at that time, there was the
greatest schism in the history of Christianity, with the
Protestant Reformation of Martin Luther. The shroud was
slightly damaged, but repaired, then. Maybe the three
comets of 1531-1533 represented the Holy Trinity: the
Father, the Son, and the Holy Ghost. So, that is why I
would not be surpised if there is a third bright comet in
2024 - 2030, but this time the comets could represent the
Unholy Trinity of Revelation: satan, the Antichrist, and
the False Prophet.
April 8 2024, Solar eclipse across the U.S.. 3 solar eclipses across the U.S. in 2017, 2024, and 2045. This Solar Eclipse could indicate a bad period for the U.S. in 2024. Look at what happened to the U.S. in 2017 when there was a solar eclipse across the U.S., the U.S. entered a dark 4 year period in 2017 ending on January 20 2021, that saw the COVID-19 epidemic, and almost ended up in dictatorship in the U.S. on January 6 2021. A previous solar eclipse that crossed the U.S. on June 8 1918 saw the U.S. in World War 1 and the 1918 Flu Epidemic. Also at this time there may be a bright comet, Comet 12P/ Pons-Brooks, also called the "Devil Comet" because it appears to have 2 horns, certainly a very ominous sign. It will likely be seen during this solar eclipse.
An interesting aspect of Comet Hale-Bopp was that it was
discovered independently by two men on the same day, July
23, 1995, in towns of New Mexico and Arizona, at the same
exact latitude North:
Alan Hale-- Cloudcroft, NM 32.96 N 105.75 W
Thomas Bopp-- Stanfield, AZ 32.88 N 111.96 W
I think the message
here is that, near the midpoint between these two
locations, is the town of Lordsburg, New Mexico, a name
with a Biblical message. One way to consider numbers, in a
religious sense, is to convert them to Biblical passage
numbers. The midpoint is at 108.85 W, and if you consider
Biblical Psalm passage 108:4,5 you have (King James
Version): "For thy mercy is great above the heavens, and
thy truth reacheth unto the clouds. Be thou exalted, O
God, above the heavens: and thy glory above all the earth."
So this Bible passage fits a comet, certainly.
If you consider the 2 states of discovery, Arizona has a
New Age connection, since Sedonna Arizona is this country's
New Age center. And Arizona's Feb. 14 birthday makes it an
Aquarius, the sign with a New Age connection. New Mexico,
however, is Capricorn. I think that that Arizona may
represent the New Age movement, while New Mexico represents
traditional Christianity; these may be the two tails (Blue
and White) of comet hale-bopp.
Both the New Age movement and Chrisitianity have Millenial
Movements. And the twin discoverers-- note that one of the
beliefs in some early Christian writings was that Jesus had
a twin brother, Thomas, who supposedly ended up in India,
giving him sort of a New Age connection. This, I think, is the message of
Comet Hale-Bopp.
If there is a
[third bright comet](comet.html) in year 2024-2030, I would not
be surprised if it is red in color.
(10) Europe and Russia, .
A woman rides the beast in Revelation 17, I think this is
[Europe-- Europa](Europe.html),, since Europa in mythology was a woman riding a bull. Putin exerts much influence over Europe by controlling natural gas supplied by Russia to Europe.
Eventually the beast will turn against Europe and burn Europa with fire, as in Revelation 17. Possibly nuclear, and biological attacks on Europe by Russia. In Revelation 17:
17:3 "...and I saw a woman sit upon a scarlet coloured beast, full of names of blasphemy, having seven heads and ten horns."
17:12 "And the ten horns which thou sawest are ten kings, which have received no kingdom as yet; but receive power as kings one hour with the beast."
17:16 "And the ten horns which thou sawest upon the beast, these shall hate the (woman), and shall make her desolate and naked, and shall eat her flesh, and burn her with fire."
(11) The Two Witnesses.
The Two Witnesses are two prophets who will appear during the end times events. They give prophecies seen over the internet and TV around the world. The beast kills them, but after three days they are resurrected and rise up into a cloud, which I think is a UFO. People are terrified when this happens.
"11:3 And I will give power unto my
two witnesses, and they shall prophesy a thousand two hundred and threescore days, clothed in sackcloth.
4 These are the two olive trees, and the two candlesticks standing before the God of the earth.
5 And if any man will hurt them, fire proceedeth out of their mouth, and devoureth their enemies: and if any man will hurt them, he must in this manner be killed.
6 These have power to shut heaven, that it rain not in the days of their prophecy: and have power over waters to turn them to blood, and to smite the earth with all plagues, as often as they will."
So watch out for two mysterious prophets who may appear
by 2024-2030. See
[this page](KingJames1d.html) for Bible Code matrices on the Two Witnesses which may indicate at least one of them is from the U.S..
The Two Witnesses: my painting shows the 2 witnesses, then a dragon sent by the beast kills them, then they are resurrected and rise into a UFO, which is what the cloud may be that they rise up into.
(12) Asteroid hitting earth. There is a possibility of an [asteroid](asteroid.html) or comet hitting earth within a few years, since it is described in Revelation 8. This is why an asteroid defense is needed, which NASA could build if they were funded to do so.
[These](KingJames11.html) King James Bible Code matrices indicate there could be an asteroid ocean hit in 2024-2030, the asteroid breaking up into 7 pieces in the atmosphere as it hits, so 7 impacts, and a giant tidal wave resulting that floods coastal cities. This could be the "seven thunders" of Revelation 10:3:
"10:3 And cried with a loud voice, as when a lion roareth: and when he had cried, seven thunders uttered their voices.
4 And when the seven thunders had uttered their voices, I was about to write: and I heard a voice from heaven saying unto me, Seal up those things which the seven thunders uttered, and write them not."
Revelation 10: An angel appears on earth. Could this be a UFO with aliens in it landing in New York City, since it lands on an ocean-land borderline, and the United Nations is in New York City. And the "seven thunders had uttered their voices" could be about an alien weapon or alien broadcast device, broadcasting a message around the world. Like the movie "The Day the Earth stood still".
My painting of the angel of Revelation 10 - note the sun-like face, holding a scroll, a rainbow above him, standing on the land and the sea, and the 7 thunders as lightning bolts:
Note that it is possible that this asteroid will break up into 7 pieces because it will be spotted ahead of time and broken up into pieces by an interceptor rocket with an atomic weapon in it, either launched by the U.S. or Russia.
Note that in February 2013 a meteorite landed in Russia with an atomic bomb size explosion.
(13) Earthquakes and Tidal waves.
There could be steadily increasing earthquakes and volcanoes in 2024 - 2030.
There is also a volcano in the Canary Islands off Africa that could collapse in a few years, producing a giant tidal wave that could hit the coasts of Africa, Spain and Portugal, the U.S. East Coast, and the Carribean; see
[this page](KingJames8.html) on King James Bible Code matrices on it. Another place there could be a giant tidal wave is from an undersea earthquake fault off the Northwest U.S., that could have a magnitude 9 earthquake causing a mega tsunami hitting Northern California, Oregon, Washington State, British Columbia, Alaska, Hawaii, and Japan. In June 2005 there were Northern California earthquakes near that under water fault zone, off Northern California and Oregon and Washington State, that brings up the possibility of a giant tidal wave occurring there, or the
[San Andreas fault](KingJames8a.html) could slip in Southern California or Northern California, hitting hard Southern California and Los Angeles or San Francisco.
**The Astrology of Diseases related to Galaxies:**
I will consider here three diseases that are a threat to
mankind: AIDS,
[Ebola](Ebola.html)
, and Influenza. The virus that causes
[AIDS](AIDS.html), HIV, was discovered in 1983, so we will associate AIDS with
the number 83. The galaxy M83 is in the constellation
Hydra, which was a multi-headed serpent in mythology that
kept growing a new head, each time a head was cut off.
This sounds like AIDS, which keeps mutating to allow it to
get around any treatment or vaccine. The Hydra was
defeated by Hercules, by his nephew Iolaus burning each of
the mortal heads as Hercules cut them off, and burying the
immortal head under a stone. I wonder if this mythology
story could somehow be a clue on how to treat AIDS? Note
that the AIDS virus has 9213=111x83 bits of genetic
information, so again we see the number 83 again.
Ebola, a lethal disease of Africa that kills in two weeks
of infection, had its virus discovered in 1976, so if we
associate galaxy M76 with it, we are near the constellation
Andromeda. Remember the movie "Andromeda Strain" about a
lethal disease that threatened humanity? That could be
Ebola if it mutates to an airborne form.
Influenza was discovered in 1933. Galaxy M33 is in the
constellation Triangulum. That may imply we should look
for a triangle. The numbers 33, 76, and 83 do form a right
(90 degree) triangle with an angle of 66 degrees.
Since
666 is the number of the antichrist, this may imply that
these three diseases will threaten humanity when he
appears. In fact, ebola virus frequently twists itself
into
a shape that looks like a "6".
These diseases may also relate to three animals used to
describe the Antichrist: he is like a leopard, has the
mouth of a lion, and the feet of a bear. Maybe Ebola
corresponds to the leopard, with its great speed; Ebola
kills in two weeks of infection.
Influenza could be the
lion; it causes coughing like a lion's roar. And AIDS
could be the bear; bears hibernate, like AIDS can do in
people, until it wakes up and kills them.
[Mad Cow Disease (BSE)](BSE.html) infecting people's brains was announced in
March 1996 in England as the Comet Hyakutake passed by the
constellation (I mean constellation, not astrological sign)
Virgo the Virgin. I think that virgo the Virgin represents
Isis, the Egyptian Goddess portrayed with cow's horns,
giving us a "cow" connection. And Virgo may also represent
Europa, representing Europe, who rides a bull, again giving
us a "cow" connection. And Europa on a bull sounds like
the woman in revelation 17 named "Babylon" who rides the
beast of the antichrist (which may be Russia), I think the woman is Europe.
Another disease, Tuberculosis (TB) is becoming an increasingly bad worldwide epidemic, with drug resistant TB common. TB also is common in cattle.
The bacteria Mycobacterium was identified by Robert Koch as the cause of TB in 1882, so we will associate the number 82 and the Galaxy M82 with it, and Revelation 18:2 (King James Version):
"18:2 And he cried mightily with a strong voice, saying, Babylon the great is fallen, is fallen, and is become the habitation of devils, and the hold of every foul spirit, and a cage of every unclean and hateful bird."
Note that TB is spread by poor sanitation and hygiene, that we can relate to the"unclean" in the passage above; and Babylon was in Iraq. And galaxy M82 is in the Great Bear constellation Ursa Major, that we can relate to Revelation 13 where the Antichrist has the mouth of a lion, feet of a bear. And the bear is the symbol of
[Russia](Russians.html), where the Antichrist Putin is in power. Also, concerning the TB bacteria discovery in 1882, see
[this page](int666.html) on how a cycle of events began in 1883.
Note: the first letters of SARS, Ebola, AIDS spells "sea", and the Antichrist (the beast) rises out of the sea (of world politics) in Revelation 13.
Also: the first letters of: Influenza, BSE, Ebola, AIDS, SARS, TB:
I BEAST
Also, SARS began in Guangdong Province, China, which is at geographic coordinates of 23 degrees North 112-115 East. Corresponding to 23 North would be the Bible's Psalm 23: (23:4, King James Version): "Yea, though I walk through the valley of the shadow of death, I will fear no evil: for thou art with me"
So this relates to this disease being the shadow of death. Also note that Hong Kong is near Guangdong Province in China, and Hong Kong is a former English colony: this may relate to the "mouth of a lion" of the Red Dragon Red China, the lion I related above to Influenza. Also note that on this site I relate the lion of the Antichrist to
[Iraq](Iraq.html), the lion being a symbol of Babylon, the ancient empire that was located in Iraq. So the war in Iraq in March 2003 may relate holographically to this "lion" disease SARS appearing then. This disease of SARS may be symbolic of the disease of Saddam Hussein that has existed in Iraq. Also, since SARS had its virus discovered in March 2003, then we can relate it to Galaxy M23, which is in the Constellation Sagittarius, Sagittarius being the half-man half-horse archer. This again would relate it to the Antichrist (who I think is Putin), since in Revelation 6:2 the Antichrist is a man on horseback with a bow and arrow. So SARS may indicate the rise of the Antichrist, the Satanic imitation of Christ, who is Vladimir Putin, to world prominence. And SARS coming out of China: the Antichrist gets his power from the dragon, indicating Putin will have an alliance with Red China, the Red Dragon. Also, corresponding to 23 for SARS (since SARS was discovered in 2003, and started near 23 North in China)would be Revelation 12:3 where the red dragon is seen in heaven. And the deadly COVID-19 Coronaviru appeared in China in 2019, so associate it with globular cluster Galaxy M19, which looks like the COVID-19 Coronavirus.
A general pattern:
Ebola: 76 (virus discovered in 1976)
Rev. 17:6, the bloodthirsty woman (Ebola makes people bleed to death)
Also in 1976: Chairman Mao dies in Red China, he was noted for being bloodthirsty, like this disease
Galaxy M76 near Andromeda ("The Andromeda Strain")
AIDS: 83 (virus discovered in 1983)
Rev. 18:3, the corrupt woman Babylon (Babylon being Iraq today)
Also in 1983: Radicalism in the Arab World is increasing, after the assassination of Anwar Sadat in 1981; Osama was in Afghanistan in 1983
Square root of 83 is 9.11, as in 9-11 (September 11)
Galaxy M83 in Constellation Hydra (the Hydra being like the Terrorists, El Qaida, it keeps growing a new head each time you cut one off, as AIDS keeps evading a vaccine)
BSE (Mad Cow Disease): 86 (discovered in 1986)
Rev. 18:6, the woman
Galaxy M86 in Virgo the Virgin, here representing the woman, who is also Isis (who had cow horns)
Tuberculosis (TB): 82 (bacteria discovered in 1882)
Rev. 18:2, the unclean city Babylon (Babylon was ancient Iraq)
Galaxy M82 in the Great Bear; the Antichrist has the feet of a bear, and the bear is Russia, where the Antichrist Putin is in power
Influenza: 33 (virus discovered in 1933)
Rev. 13:3, the beast (the Antichrist) rises out of the sea
Galaxy M33 in Triangulum
In 1918, world flu epidemic, as the Red Beast formed in Russia with the Russian Revolution (the beginning of the Antichrist's Evil Empire in Russia). And a bird flu virus infecting chickens and birds in Asia is a concern, since it could mutate and combine with swine flu and become a human pandemic.
The Swine Flu virus spreading in 2024 - 2030 could combine with Bird Flu, creating a more deadly virus.
SARS: 23 (virus discovered in 2003)
Began near 23 degrees North in China
Rev. 12:3, the Red Dragon seen in heaven
Galaxy M23 in Sagittarius, the Archer horse/man, corresponding to the man on horseback with a bow in Revelation 6:2, the Antichrist
Coronavirus COVID-19: 19. Virus discovered in December 2019 in China, so Galaxy M19 in Constellation Ophiucus, the man holding a snake. Snake - the dragon in Revelation 13, the Coronavirus came from China, the dragon. Also snake - the Antichrist Putin. Galaxy M19 is a globular cluster that looks like a Coronavirus particle. This is the 4th horseman Death riding in 2024-2030. Note that it is believed this Coronavirus came from a Horseshoe Bat that is the carrier, and was being sold in a Chinese market. Note the name HorseShoe Bat - perhaps this is the horseshoe of the Fourth Horseman Death, a pale horse, in the Bible's Book of Revelation 6:8.
Generally, the prophecies discussed on this site may be changeable, if people will understand and listen to them and take appropriate action, such as building an asteroid defense. This may be a test for the human race: if people will understand that the disasters described in Revelation are occurring, then it may be possible to change the future and avoid these disasters.
In this web site I have tried to show how astrology, new age methods, religion, bible prophecy, the King James Bible Code, and mythology can be used in a combined way, to explain the world today and to predict the future. I try to find a middle way, between Christianity and New Age, because I think that is where the truth is. A middle way, as in Buddhism where a middle way between extremes is emphasized. And as in Hinduism, I have looked to Astrology and the stars for guidance. And the idea of a unifying religion is advocated here, as the Baha'i faith has a goal of unifying mankind; Baha'i is one of the most enlightened of world religions; begun in Iran, its world headquarters is in Haifa, Israel.
The truth is found by following the Middle Way between religions, and that is the path I have tried to follow here. John 8:32: "And ye shall know the truth, and the truth shall make you free".
-------------------------------------------------------
Please link to this web site! To help me spread my message to the world! This site is:
http://revelation13.net
Title: "Revelation13.net: Astrology, Prophecies of the Future, Bible Prophecy and the Book of Revelation, the King James Bible Code"
If you would like to use a banner in your link to my site, there are several at [this page](banners.html).
Thanks!
About the author of this site: My name is T. Chase, and I live in the U.S.. I grew up in the U.S. as a Christian Protestant, and I am of English Anglo-Saxon ancestry, but today I would call myself a New Age Christian. This site is a one person effort by me, and the theories and opinions expressed on this site are my own. I have worked on my theories for 26 years, and I started a web site in 1998 to explain my theories to the world.
And did I find any King James Bible Code matrices of interest for my own name and this web site? I tried as an experiment running a Bible Code search on my own name and the name of this web site, since it seems that so many things can be looked up in it.
Concerning this web site, this New Testament King James Bible Code matrix, at John 14:23 - Revelation 7:9, was found by searching for REVELATION THIRTEEN (since "Revelation13.net" is the name of this web site), my name TCHASE, and also note in this matrix there is: WEB (as in web site), AND WE HAVE SEEN, LOOKING FOR THAT BLESSED HOPE, THE SPIRIT OF THE WORLD, TO SPEAK UNTO THE PEOPLE, THEY TOOK KNOWLEDGE, BE REVEALED, THE TRUTH. I think these words describe what this web site Revelation13.net is about. John 8:32: "And ye shall know the truth, and the truth shall make you free".
On psychic powers: I am an amateur psychic.
You can watch
[on this page](psychic.html) videos where I demonstrate telekinesis, how I use my psychic telekinetic power to make clouds disappear at will.
Years ago when I saw an extremely powerful psychic, it was said to me:
"-- I would see you as the pied piper, the guide, the person that is probably more psychic than any of the psychics you have gone to in your life.
-- As you go through life you are supposed to share wisdom. Your destiny is to teach, to lead, to be the guide. It is said that when the student is ready to teach you shall appear. That you move by Mars and Pluto, which is a sign of the upheaval."
Relating to my own psychic powers, I found this New Testament King James matrix at Mark 4:15 to Luke 21:29. The search words were: PSYCHIC, TCHASE, PROPHET, BEAST (since my web site is about the Beast, the Antichrist). Also, other phrases found in this matrix:
- AND HE CAME BY THE SPIRIT
- COME OUT OF THE MAN THOU UNCLEAN SPIRIT
- HE SPAKE TO THEM A PARABLE
- THUS SPAKE THERE CAME A CLOUD AND OVERSHADOWED THEM
- BUT PERCEIVEST NOT THE BEAM THAT IS IN THINE OWN EYE (which sounds like psychic vision, a psychic beam)
-------------------------------------------------------
Bible quotes are from the King James Version Bible.
Copyright 1998-2023 by T. Chase. All rights reserved.
"I came, I saw, I built a web site."
Email T. Chase at: tchase800@aol.com
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<meta name="keywords" content="ANCIENT EGYPTIAN TIMELINE, Introduction, evidence, human, occupation, Land, Egypt, c. 200,000 BC ,, Nomadic, , Hunter Gatherer, stage, human, evolution, last Ice Age c. 10,000 BC, climatic change, temperate zones, appear, allowing, agriculture, Sun ,and ,annual inundation, river Nile, Villages, Central Communities, emerge,. Boats, first ,made, papyrus,; secondary wood,. ,river ,Nile ,served, central, trade route, exchange, gold, pottery ,other, cultural ,expressions, develop, era, Predynastic, Period of Egypt, c. 5500, BC begins,. Egypts, two, separate, kingdoms, Lower Egypt (Delta), and, Upper Egypt, are, relative terms, flow, river Nile,. Early ,Dynastic Period, of ,Egypt c. 3100 BC, unifies, Lower, and, Upper Egypt,. The Capital, & ,Royal Court ,are, based in, Memphis, Abydos ,Main Necropolis,. Order From Chaos, PREDYNASTIC PERIOD c. 5500 BCc. 3100 BC, Upper and Lower Egypt,; Distinct, Anatomical Differences,; Separate, Gods, evolve ,into, assimilated ,Gods,; Sacred Symbols,,Lotus, & ,Papyrus,. Death-Rebirth Cycle, of ,two, great, natural, elements, / ,forces, =,Sun, and the, Nile,. Afterlife ,and, Funerary Rituals,Bodies, placed, facing ,WestSunset,. Earliest ,body, preservation,,shrouded, laid, in, desert sand,. Migrants, Nubia, Palestine, & ,Syria,. Migration, to the, North of Egypt, (,Lower Egypt,)., Hieroglyphs [1] ,develop, c. 3400 BC. EARLY DYNASTIC PERIOD c. 3100 BCc. 2686 BC ,First ,and Second Dynasties,: ,Narmer,(,Menes, possibly, same person,) ,First Ruler of Dynastic Period,. ,Scorpion,,One ,of the, last Rulers, of this, period,. Kingship, develops,secular power, over, Two Lands, and, identify themselves, embodiment, Gods,; Horus, Sun God Re, Son ,of Re. Capital, &, Royal Court-Memphis,; ,Abydos ,is,Main Necropolis,. Mastaba Tombs, built, mudbrick, Mortuary Temples, housed, the, Deceaseds ka,; a ,Spirit Force, surviving death,., Stelae, is, an, inscribed ,slab, inside ,and, outside, of ,Tombs, and ,Temples, depicting ,information, particular ,King Deity, associated, him,. First, calendrical, system, based ,astronomical ,measurements, Hieratic Script, developed,. ,OLD KINGDOM, c. 2686 BCc. 2181 BC Third Sixth Dynasties,: , Sophistication, of ,Society Pharaonic, era begins,. Technology, advances, culture,. Imhotep, vizier, to, King Djoser, designs the first, Stepped Pyramid, c. 2650, known, Djosers Stepped Pyramid, located in Saqqara, constructed, stone ,built ,by ,Egyptians, who, believed ,their, Afterlife ,dependent, glories, their, Kings Funerary ,Monument,; Pyramid,., What, visualize, True, Pyramids, were, built 4th Dynasty, Giza Plateau,. First, The Great Pyramid, supposedly, built, Khufu, Second, Pyramid-Khafre, Third ,Pyramid-Menkaure, near, Great Sphinx, date, construction, deemed by, Orthodox Egyptologists, view, c. Khafre, Nemes Headcloth, ceremonial, false beard, part, Royal regalia,. Even Isis, known wear, a beard portray, her Pharaoh,. Boats, played, a, significant, role, funerary beliefs,. The, Sun God Re, was, believed to, travel through, skies, Underworld Solar, Barque, vessel-boat, after death, King, thought ,embark ,similar journey, 1200, pieces wood, material, used, vessel, uncovered in, Giza, in 1954, 10 years, reconstruct, possibly ,Khufus ,funerary, Barque, vessel, traveling across, Nile, from, East to West, ritualistic, Sun, rising, East ,setting West, reason causeways of Mortuary Temples, began, being ,situated on the Eastern Face ,Pyramid, of, Kings, leading ,riverbanks, river Nile ,causeways ,used , transporting, materials, across the Nile,. FIRST INTERMEDIATE PERIOD, c. 2181 BCc. 2055 BC SeventhEleventh Dynasties, Long ,periods, instability ,due , provincial, rules warring ,control,. Political, upheaval ,decline, in ,economics, famine, prevails,. A, rise, prominence, Osiris, time, due, need ,survival, belief, resurrection,; time all ,Egypt, both, Upper and Lower, state of ,despair,. The Rulers, originated, from, Herakleopolis, during the, 9th Dynasty ,gained, control conflict, Theban Princes, later gained ,either diplomatic, military, victory, over, Herakleopolis Rulers, Mentuhotep, II founded, 11th Dynasty, creating ,order ,once again, prosperity, finally ,restored, Egypt, Osirian, Legend, performed, remarkable, trend, belief, following,. The Royal Court, moved, Thebes during, time, MIDDLE KINGDOM , c. 2055 BCc. 1650 BC Eleventh,, Fourteenth Dynasties, The ,second, great, era, of, Egypt ,with, the, Golden Age, of, prosperity, and, achievement. Amenemhat ,I was, founder ,of the, 12th Dynasty, and Itjtawy, becomes, the new, Capital of Egypt,. Karnak, was ,established ,through ,Osiris Amun , pre-eminent era,. Abydos, most important, pilgrim center, trade political, standing,. Later, another, decline Egypt, migrating, Middle Easterners,, t ,Hyksos, invade, settle Egypt,. era began, age of Bronze, smelting,. SECOND, INTERMEDIATE PERIOD , c. 1650 BCc. 1550 BC ,Fifteenth,,Seventeenth Dynasties , Hyksos, ruled, established ,themselves ,Capital, Avaris ,Delta, Upper Egypt, Indigenous, Rulers ,held, other, territories, Egypt, began, to ,decline, central ,power, Hyksos ,bring ,new ,era, Egypt, brought, arts, culture,. first era, see ,chariot, advancement military, technology horse, lute, lyre ,came, 16th Dynasty During, 17th Dynasty, the ,Hyksos ,ruled, Thebes, However ,tension ,decline, power ,Theban Princes ,conquered Hyksos, Egypt, hands ,native peoples, 18th Dynasty ,founded, under ,Ahmose I,. NEW KINGDOM , c. 1550 BCc. 1070 BC Eighteenth,Twentieth Dynasties , Theban, God Amun ,attributed, to the, new era ,of,Egypt ,and ,prosperity, after ,the ,expulsion ,Hyksos,. Amun ,synchronizes, with, Re Amun-Re, now, Eminent Deity, much ,Amun Re, in the, Karnak ,Temple ,Luxor, and the ,surrounding ,great, Temples, built times, circumscribing ,three, dynasties,. Tuthmosis III,, Egypts, greatest, Warrior, King ,expansion, annexing, of, Nubia, Palestine ,and Syria,. The Solar Deity Aten, becomes, popular, cult ,under ,ruling of, Amenhotep IV, proscribed ,Gods,. Amenhotep IV, changes name, Akhenaten ,moves, Royal Court, modern day ,area ,o,f Tell el Amarna,. Later ,Tutankhamun, restored, traditional pantheon,. Rameses I ,founded the, 19th Dynasty ,Qantir Capital, invasions, Libyans, Nubians, others, create chaos, ; Egypt, prevails, Valley of the Kings, Thebes, established, Royal Necropolis, Ramessid Era ,tremendous ,hardships, civil economic, unrest , Royal Authority, declined ,Cult of Osiris & Isis, most ,prominent, New Kingdom, c. 1550 BC 1070 BC,. ,THIRD INTERMEDIATE PERIOD, c. 1070 BCc. 747 BC ,Twenty-first,,Twenty-fourth Dynasties, Smendes, founded ,21st Dynasty ,Tanis, Delta ,Capital,. The ,High Priests Amun, rule ,Southern ,Egypt ,Thebes,. Later, two lineages ,marry, blend, helping, rivalry, of ,Lower and Upper Egypt,. Egypt, is, united, once, again, ruled, under ,concurrent, powers, dominant ,power, Delta, was, Sais,. Piy Ruler, Southern Kingdom Napata, Capital,. New age, Iron, working ,LATE PERIOD , c. 747 BCc. 332 BC ,Twenty-fifth,-,Thirtieth Dynasties, Shabaqo, Napata ,conquered ,whole, of, Egypt founded, 25th Dynasty,. ,Assyrians, invaded ,established, Saite ,Lineage, rule, Egypt Babylonia, rises, power, wipes ,Assyrians, Persia, invades ,Assyrians, dominant, power, 26th Dynasty, established,,. Egyptian ,Natives, finally, expel, Persians Saite, leader, known ,Amyrtaios,. Invasions, and, conquests ,during, s, time, change Rulers,. Lineage Mendes, founds, 29th ,Dynasty,. Nectanebo, I, re-conquers, Egypt,. Finalize, era, Alexander the Great, invaded, Egypt Egypt ,falls, control Greeks,; Alexandria, becomes ,new, Capital,. GRAECO-ROMAN, PERIOD , c. 332 BCAD 641, Alexandria ,& ,Beyond , Alexander the Great ,conquered ,Egypt ,glories ,Macedonians, ruling Egypt, yet, this ,was a ,welcomed, occupation, as they had, driven, the, Persian invaders, out of ,Egypt ,bound ,caused ,great decline, Alexandria, great ,Capital City, housing, Great Alexandria Library ,famous, burning ground, during, Roman, invasion ,c. 30 BC, somewhere ,reign ,Cleopatra VII,. Previous ,Roman invasion, Egypt ,ruled, under ,Ptolemies, long lineage, descended, from, Alexanders, great Generals,. ,Kings, assumed, role of Pharaoh, an era ,great ,Temple building,. In, 196 BC ,decree, commemorating, Ptolemy Vs coronation, ; slab, inscribed basalt, depicts, decree, later ,found ,French soldier, Pierre Poushar, 1799, Rosetta , a ,small village, near ,river Nile , known ,Rosetta Stone ,Temples at Dendera, show ,magnificent, hieroglyphics, era, occupation, Caesar, Mark Antony, and, Cleopatra,. Dendera ,known ,great Temple of Hathor, amazing, Ceiling Zodiac,. Beginning, ruling ,under, Rome Octavian ,invaded, Egypt, main purpose, rich, grain ,Christianity spread, through ,Egypt during time, Constantine,. Greek, still remained, official ,language ,until, Arabs, invaded D 641, Islam, became ,predominant Religion, Language ,Christianity remained, influence ,Coptic, Church, Coptic Church, Islamic modern, day, Muslim ,recognized, in, modern day, Egypt, along ,with ,other, nationalities, and, faiths,. Cairo, now ,Main Necropolis ,Capital Egypt, located Upper Land, Delta Egypt,. Giza, small ,town next, Cairo, Great Pyramid, the, Great Sphinx, located, next ,river, Nile , now, modern Egypt, Circular Times, Robert Schoch, Colette Dowell ,Website, Homepage, Angela Praxter, Professional Assistant, Intellectual, Scientific, Philosophical, Spiritual , Institute, ">
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<font face="Arial" size="1">Ancient Egyptian Timeline Old-New Kingdom timeline
in simple form to understand Pre Dynastic to New Kingdom, Upper and Lower Egypt
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<img border="0" src="CTGw81.jpg" width="81" height="87" align="left" hspace="10" longdesc="Colette Dowell Circular Times Alternative Magazine Published Since 1995" alt="Colette Dowell Circular Times Alternative Magazine Published Since 1995"></a><span style="font-weight: 700"><font color="#000000" style="font-size: 16pt"><a href="index.html"><font color="#000000">CIRCULAR
TIMES</font></a></font></span></p>
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I</span>ntellectual, Scientific and Philosophical Studies</font></p>
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<a href="Jewelry%20Egyptian%20Antique%20Maya%20Inca%20Far%20East%20India%20Native%20American%20European%20Africa%20Collector%20Handmade%20Silver%20Gold%20Motif.htm">
<font color="#6666FF">Sabu Enter Here</font></a></font><font size="5" color="#6666FF">
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<p class="MsoNormal" align="center"> <b><font face="Emboss" size="6">A
SURREALISTIC VIEW OF</font></b></p>
<p class="MsoNormal" align="center"><b><font face="Emboss" size="6">ANCIENT
EGYPT'S TIMELINE</font></b></p>
<p class="MsoNormal" align="center"><b><font face="Emboss" size="4">
<a href="mailto:cosmicgalas@gmail.com?subject=From your Website">
<font color="#800000">by Dr. Colette M. Dowell</font></a></font></b></p>
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<img border="0" src="ESMTPbt700.jpg" width="700" height="422" longdesc="Image of Sphinx body and face Valley Temple and Khafre Pyramid photograph by Colette Dowell ancient EGyptian timeline article in Circular Times Pyramids, Ancient wisdom teachings UFOs aliens maybe who knows and crop circle hoaxes Bosnian Pyramid" alt="Image of Sphinx body and face Valley Temple and Khafre Pyramid photograph by Colette Dowell"></p></div>
<p class="MsoNormal" align="center"><b><i><font face="Caxton Bk BT" size="4"> </font></i></b></p>
<p class="MsoNormal" align="center"><b>
<font face="Emboss" style="font-size: 16pt">Preface</font></b></p>
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<font size="3" face="Courier New">Many times I stumble on Egyptian jargon of
Pre-Dynastic this and which Dynasty that, Old Kingdom in Lower Egypt (Delta) vs.
New Kingdom in Upper Egypt, Ra, Isis, Horus, Akhenaten, Khufu or Khafre, or none
at all, Temple or Mastaba, this or that and so on and so forth. Hence, I decided
to make a simple timeline including a few Egyptian concepts and historical
venues. This little Egyptian timeline serves a simple purpose by keeping things
simple and if there is a need to complicate things a bit more, well at least
there is a guide and timeframe to go by that is not too overwhelming to
comprehend. I have bold typed key words to impress them in the mind as they seem
to be of importance to understand Egypts development through her most
controversial times. I hope this helps you too. Colette Dowell </font></p>
<p class="MsoNormal" align="center"> </p>
<p class="MsoNormal" align="center"><b>
<font face="Emboss" size="6">ANCIENT EGYPTIAN TIMELINE</font></b></p>
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<font face="Caxton Bk BT"><span style="font-size: 8.0pt"> </span></font></p>
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<font face="Emboss"><b><span style="font-size: 16.0pt">Introduction</span></b></font></p>
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<font face="Caxton Bk BT"><b><span style="font-size: 8.0pt"> </span></b></font></p>
<p class="MsoNormal" align="justify"><font face="Caxton Bk BT">
</font><font face="Courier New" size="3">There is evidence of human occupation
in the Land of Egypt <i>c</i>. 200,000 BC , being that of the Nomadic Hunter
Gatherer stage of human evolution. After the last <b>Ice Age <i>c</i>. 10,000 BC</b>,
<b>climatic change begins and temperate zones appear</b> allowing agriculture
possible due to the <b>Sun</b> and annual inundation of the river <b>Nile</b>,
where Villages and Central Communities begin to emerge. Boats were first made
from papyrus; secondary wood. The river <b>Nile</b> served as a <b>central trade route</b> for
exchange of gold, pottery and other cultural expressions that began to develop
and the era of the <b>Predynastic Period</b> of <b>Egypt <i>c</i>. 5500 BC
begins</b>. Egypts two separate kingdoms, <b>Lower Egypt</b> (Delta) and <b>
Upper Egypt</b>, are relative in terms to the flow of the river Nile. <b>The
Early Dynastic Period of Egypt <i>c</i>. 3100 BC unifies Lower and Upper Egypt.</b>
The <b>Capital</b> <b>&</b> <b>Royal Court</b> are based in <b>Memphis</b>, and
<b>Abydos</b> is the <b>Main Necropolis</b>.</font></p>
<p class="MsoNormal" align="justify"> </p>
<p class="MsoNormal" align="center">
<img border="0" src="ENileA566.JPG" width="566" height="325" longdesc="Image of Nile River Egypt near Luxor photograph by Colette Dowell article of ancient Egyptian timeline for pyramids, Sphinx, Temples, more hieorglyphics" alt="Image of Nile River Egypt near Luxor photograph by Colette Dowell"></p>
<p class="MsoNormal"><font face="Courier New" size="4"> </font></p>
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<font face="Emboss" size="5"><b>Order From Chaos</b></font></p>
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<font face="Caxton Bk BT"><span style="font-size: 18.0pt; font-weight: 700"> </span></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">PREDYNASTIC PERIOD <i>
c</i>. 5500 BC<i>c</i>. 3100 BC</span></b></font></p>
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<font face="Courier New"><b><u>
<span style="text-decoration: none; font-size: 8.0pt"> </span></u></b></font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New">Upper and Lower Egypt; Distinct Anatomical Differences;
Separate Gods evolve into assimilated Gods; <b>Sacred Symbols</b><b>Lotus &
Papyrus</b>. <b>Death-Rebirth Cycle </b>of <b>two great natural elements /
forces</b> = <b>Sun</b> and the <b>Nile</b>. <b>Afterlife and Funerary Rituals</b>Bodies
placed facing <b>WestSunset</b>. Earliest body preservationshrouded and laid
in desert sand. <b>Migrants</b> from <b>Nubia</b>, <b>Palestine</b> &
<b>Syria</b>. Migration to the North
of Egypt (Lower Egypt). <b>Hieroglyphs develop <i>c</i>. 3400 BC.</b></font></p>
<p class="MsoNormal"><font face="Courier New"><b>
<span style="font-size: 14.0pt"> </span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">EARLY DYNASTIC PERIOD
<i>c</i>. 3100 BC<i>c</i>. 2686 BC</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">First and Second
Dynasties:</span></b></font></p>
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<font face="Courier New"><b><u>
<span style="text-decoration: none; font-size: 8.0pt"> </span></u></b></font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New"><b>Narmer </b>(<b>Menes</b>, possibly same person) <b>
First Ruler</b> of <b>Dynastic Period. Scorpion </b>One of the last Rulers of
this period. <b>Kingship</b> develops secular power over <b>Two Lands</b> and
identify themselves as an embodiment with Gods; <b>Horus</b>, the <b>Sun God Re</b>
and the <b>Son of Re</b>. <b>Capital</b> <b>&</b> <b>Royal Court</b>-<b>Memphis;</b>
<b>Abydos is Main Necropolis</b>. <b>Mastaba Tombs</b> built from <b>mudbrick</b>
and <b>Mortuary Temples </b>housed the Deceaseds <b><i>ka</i>;</b> <b>a</b> <b>
Spirit Force surviving death</b>. <b>Stelae</b> is an inscribed slab inside and
outside of Tombs and Temples depicting <b>information</b> of that particular <b>
King</b> and <b>Deity</b> associated with him. First calendrical system based on
astronomical measurements and <b>Hieratic Script</b> developed.</font></p>
<p class="MsoNormal" align="justify"><font face="Courier New">
<span style="font-size: 14.0pt"> </span></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">OLD KINGDOM <i>c</i>.
2686 BC<i>c</i>. 2181 BC</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">Third Sixth
Dynasties:</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><u>
<span style="text-decoration: none; font-size: 8.0pt"> </span></u></b></font></p>
<p class="MsoNormal" align="center" style="text-align: justify">
<font face="Courier New"> Sophistication of Society and
<b>Pharaonic</b> era begins. Technology advances along with culture. <b>Imhotep</b>,
vizier to <b>King Djoser</b>, designs the <b>first Stepped Pyramid, <i>c</i>.
2650</b>, known as <b>Djosers Stepped Pyramid</b>, located in <b>Saqqara</b>,
constructed by stone and built by Egyptians who believed their <b>Afterlife</b>
was dependent on the glories of their <b>Kings Funerary Monument</b>; the <b>
Pyramid</b>.</font></p>
<p class="MsoNormal" align="center" style="text-align: justify">
</p>
<p class="MsoNormal" align="center">
<img border="0" src="EMTKP320.jpg" width="550" height="320" longdesc="Valley Temple Khafre Pyramid Giza Egypt photograph by Colette Dowell ancient Egyptian timeline article in Circular Times Mag" alt="Image of Valley Temple Khafre Pyramid Giza Egypt photograph by Colette Dowell"></p>
<p class="MsoNormal" align="center" style="text-align: justify"> </p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New">What we <b>visualize</b> as <b>True Pyramids</b> were
built in the <b>4<sup>th</sup> Dynasty</b> on the <b>Giza Plateau</b>. The first
of these, <b>The Great Pyramid</b>, supposedly was built by <b>Khufu</b>, the
<b>Second Pyramid-Khafre</b> and the <b>Third Pyramid-Menkaure</b>, near the <b>
Great Sphinx</b>, whose date of construction deemed by <b>Orthodox
Egyptologists</b> view is that of <b><i>c</i>. Khafre</b>.</font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify"> </p>
<p class="MsoNormal" align="justify"><font face="Courier New">
The <b>Nemes Headcloth</b> and <b>ceremonial false beard</b> was part of the <b>
Royal regalia</b>. Even <b>Isis</b> was known to wear a <b>beard</b> to <b>
portray</b> her as a <b>Pharaoh</b>. Boats played a significant role in the
funerary beliefs. The <b>Sun God Re </b>was believed to travel through the skies
and the <b>Underworld</b> by the <b>Solar Barque</b>, (vessel-boat) and after
death the <b>King</b> was thought to embark on a <b>similar journey</b>. 1200
pieces of wood, material used for a vessel was uncovered in <b>Giza</b> in <b>1954</b>,
taking 10 years to reconstruct what is possibly <b>Khufus funerary Barque</b>
or vessel. The <b>traveling across</b> the <b>Nile from East to West</b> was
ritualistic as the <b>Sun rising in the East and setting in the West</b>. For
this reason the <b>causeways</b> of <b>Mortuary Temples</b> began being situated on the
<b>Eastern Face</b> of the <b>Pyramid</b> of Kings, <b>leading to the riverbanks</b> of the river
<b>Nile</b>. These causeways were also used for transporting materials across the Nile.</font></p>
<p class="MsoNormal"><font face="Courier New"><span style="font-size: 14.0pt"> </span></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">FIRST INTERMEDIATE
PERIOD <i>c.</i> 2181 BC<i>c</i>. 2055 BC</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">Seventh Eleventh
Dynasties</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 8.0pt"> </span></b></font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New">Long periods of instability due to provincial rules
warring for control. Political upheaval and decline in economics, famine
prevails. There was a <b>rise</b> in the <b>prominence</b> of <b>Osiris</b> during this time, most
likely due to the <b>need of survival</b> and the <b>belief of resurrection</b>; as of this
time all of Egypt, both <b>Upper</b> and <b>Lower</b> were in a state of <b>despair</b>. The <b>
Rulers</b> who originated from <b>Herakleopolis</b> during the <b>9<sup>th</sup>
Dynasty gained control</b> and were in conflict with <b>Theban Princes</b>,
later who <b>gained</b> either the diplomatic or military <b>victory</b> over the
<b>Herakleopolis Rulers.</b> <b>Mentuhotep II</b> founded the <b>11<sup>th</sup>
Dynasty</b> <b>creating order</b> once again and <b>prosperity</b> was finally
<b>restored to
Egypt</b>, thus the <b>Osirian Legend</b> performed a remarkable trend of belief and
following. <b>The Royal Court</b> was moved to <b>Thebes</b> during this time.</font></p>
<p class="MsoNormal"><font face="Courier New"><span style="font-size: 14.0pt"> </span></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">MIDDLE KINGDOM <i>c</i>.
2055 BC<i>c</i>. 1650 BC</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">Eleventh Fourteenth
Dynasties</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><u>
<span style="text-decoration: none; font-size: 8.0pt"> </span></u></b></font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New">The <b>second great era</b> of <b>Egyp</b>t with the <b>Golden Age</b>
of prosperity and achievement. <b>Amenemhat I</b> was founder of the <b>12<sup>th</sup>
Dynasty</b> and <b>Itjtawy </b>becomes the new <b>Capital</b> of <b>Egypt</b>.
<b>Karnak</b> was established through <b>Osiris</b> and <b>Amun</b> was
pre-eminent in this era. <b>Abydos</b> was the most important pilgrim <b>center</b> of
<b>trade</b> and <b>political</b> standing. <b>Later</b> another <b>decline</b> set into Egypt as the
<b>migrating</b> <b>Middle Easterners</b>, the <b>Hyksos</b> <b>invade</b> and <b>settle</b>
in <b>Egypt</b>. This era <b>began</b> the age of <b>Bronze</b> smelting.</font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="center">
</p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="center">
<font face="Courier New"><b><span style="font-size: 14.0pt">
<img border="0" src="EKnkHaT397.JPG" width="597" height="397" longdesc="Image of Hieroglyphics Hieroglyphs honey bees and flyiing wasps hornets Karnak Temple in Luxor Egypt photograph by Colette Dowell ancient EGyptian timeline in Circular Times ALternative Magazine, EGypt, pyramids, Shpinx, archaeology, astronomy, Robert Schoch, Gerald Hawkins, and more some paranormal UFOs aliens crop circles Bosnia Pyramid" alt="Image of Hieroglyphics Hieroglyphs honey bees and flyiing wasps hornets Karnak Temple in Luxor Egypt photograph by Colette Dowell"> </span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
</p>
<p class="MsoNormal" align="center">
<font face="Courier New"><b><span style="font-size: 16pt">SECOND INTERMEDIATE
PERIOD <i>c</i>. 1650 BC<i>c</i>. 1550 BC</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">Fifteenth
Seventeenth Dynasties</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><u>
<span style="text-decoration: none; font-size: 8.0pt"> </span></u></font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New">The <b>Hyksos</b> ruled and established themselves with
a <b>Capital</b> in <b>Avaris</b> in the <b>Delta</b> (<b>Upper Egypt</b>),
while other <b>Indigenous Rulers</b> held <b>other territories</b>. <b>Egypt</b> began
to <b>decline</b> again in central <b>power</b>. However the <b>Hyksos</b> did bring in a
<b>new era</b> for
Egypt as they brought in <b>arts</b>, and <b>culture</b>. This was the <b>first</b> era to see
the <b>chariot </b>and advancement in <b>military technology</b>. The <b>horse</b>, <b>
lute</b> and <b>lyre</b> came in the <b>16<sup>th</sup> Dynasty</b>. During the
<b>17<sup>th</sup>
Dynasty</b> the <b>Hyksos </b>ruled from <b>Thebes</b>. However there was so much
tension and decline of power the <b>Theban Princes</b> <b>conquered</b> the <b>Hyksos</b> so
once again <b>Egypt</b> was in the <b>hands</b> of her <b>native</b> peoples. The <b>18<sup>th</sup>
Dynasty</b> was founded under <b>Ahmose I</b>.</font></p>
<p class="MsoNormal"><font face="Courier New"> </font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">NEW KINGDOM <i>c</i>.
1550 BC<i>c</i>. 1070 BC</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">Eighteenth Twentieth
Dynasties</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><u>
<span style="text-decoration: none; font-size: 8.0pt"> </span></u></b></font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New"><b>Theban God Amun </b>was attributed to the <b>new era of
Egypt</b> and prosperity <b>after</b> the expulsion of the <b>Hyksos</b>. <b>Amun synchronizes
with Re</b> and <b>Amun-Re</b> was now the <b>Eminent Deity</b>. You see much of
<b>Amun Re</b> in the <b>Karnak</b> <b>Temple</b> as well as that of <b>Luxor</b>
and the surrounding great <b>Temples</b> built in the times circumscribing these
three dynasties. <b>Tuthmosis III</b> is Egypts greatest <b>Warrior King</b>
and expansion with <b>annexing</b> of <b>Nubia</b>, <b>Palestine</b> and <b>
Syria</b>. The <b>Solar Deity Aten</b>, becomes a very <b>popular cult</b> under the
ruling of <b>Amenhotep IV</b>, who proscribed all other Gods.</font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="center">
</p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="center">
<font face="Courier New">
<img border="0" src="ELxStAZ604.JPG" width="604" height="454" longdesc="Image of Rameses III Luxor Temple Luxor Egypt photograph by Colette Dowell article for ancient Egyptian timeline paper in Circular Times" alt="Image of Rameses III Luxor Temple Luxor Egypt photograph by Colette Dowell"></font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="center">
<font face="Courier New"> </font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New"><b>Amenhotep IV changes his name to Akhenaten</b> and
moves the <b>Royal Court</b> to modern day area of <b>Tell el Amarna</b>. Later
<b>Tutankhamun</b> <b>restored</b> the <b>traditional pantheon</b>. <b>Rameses I</b> founded
the <b>19<sup>th</sup> Dynasty</b> and now <b>Qantir</b> is new <b>Capital</b>.
Many <b>invasions</b> by <b>Libyans</b>, <b>Nubians</b> and others to <b>create chaos</b>;
<b>Egypt prevails</b>. <b>Valley of the Kings</b> at <b>Thebes</b> is established as
the <b>Royal Necropolis</b>. The <b>Ramessid Era</b> had seen tremendous
<b>hardships</b> and civil and economic <b>unrest</b> while the <b>Royal Authority declined</b>.
The <b>Cult of Osiris & Isis</b> became most prominent in the <b>New Kingdom, <i>
c</i>. 1550 BC 1070 BC</b>.</font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 14.0pt"> </span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">
<a href="Jewelry%20Egyptian%20Antique%20Maya%20Inca%20Far%20East%20India%20Native%20American%20European%20Africa%20Collector%20Handmade%20Silver%20Gold%20Motif.htm">
<img border="0" src="SABU%20c120.JPG" width="120" height="176" align="right" hspace="10" longdesc="Image Egyptian antique jewelry gold silver pearls beads Collectors handmade and custom by Colette Dowell for Sabu Designs all fine costume jewelry inspired by world travels and museums native shops European jewelry castlesin Europe and Russia" alt="Image Egyptian antique jewelry gold silver pearls beads Collectors handmade and custom by Colette Dowell for Sabu Designs all fine costume jewelry inspired by world travels and museums native shops European jewelry castlesin Europe and Russia"></a>THIRD INTERMEDIATE
PERIOD <i>c</i>. 1070 BC<i>c</i>. 747 BC</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">Twentyfirst
Twentyfourth Dynasties</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><u>
<span style="text-decoration: none; font-size: 8.0pt"> </span></u></b></font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New"><b>Smendes</b> founded <b>21<sup>st</sup> Dynasty</b>
and <b>Tanis</b> in the <b>Delta</b> is ruling <b>Capital</b>. The <b>High
Priests </b>of <b>Amun rule Southern Egypt from Thebes</b>. Later <b>two lineages
marry</b> and blend, helping the rivalry of <b>Lower and Upper Egypt</b>. <b>Egypt</b> is
<b>united</b>
once again while being ruled under concurrent powers. The dominant power in the
<b>Delta</b> was that of <b>Sais</b>. <b>Piy</b> was <b>Ruler</b> of the <b>
Southern Kingdom</b> and <b>Napata</b> is <b>Capital</b>. New age of <b>Iron</b>
working.</font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="left"> </p>
<p class="MsoNormal" align="center" style="text-align:center">
<font face="Courier New"><b><span style="font-size: 16pt">LATE PERIOD <i>c</i>.
747 BC<i>c</i>. 332 BC</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align:center">
<font face="Courier New"><b><span style="font-size: 16pt">Twentyfifth -
Thirtieth Dynasties</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align:center">
<font face="Courier New"><b><u>
<span style="text-decoration: none; font-size: 8.0pt"> </span></u></b></font></p>
<p class="MsoNormal" align="center" style="text-align: justify"><b>
<span style="font-family: Courier New"><font size="3"> Shabaqo</font></span></b><span style="font-family: Courier New"><font size="3">
from </font></span><b><span style="font-family: Courier New"><font size="3">
Napata</font></span></b><span style="font-family: Courier New"><font size="3">
conquered the whole of Egypt and founded the <b>25<sup>th</sup> Dynasty</b>. <b>
Assyrians</b> <b>invaded</b> and established <b>Saite Lineage</b> to <b>rule Egypt</b>. </font>
</span><b><span style="font-family: Courier New"><font size="3">Babylonia</font></span></b><span style="font-family: Courier New"><font size="3">
rises to <b>power</b> and <b>wipes out</b> the <b>Assyrians</b>, then </font></span><b>
<span style="font-family: Courier New"><font size="3">Persia</font></span></b><span style="font-family: Courier New"><font size="3">
<b>invades</b> the <b>Assyrians</b> as <b>dominant power</b> and the <b>26<sup>th</sup>
Dynasty</b> is established. The <b>Egyptian Natives</b> however finally <b>expel</b>
the <b>Persians</b> by the <b>Saite</b> leader known as <b>Amyrtaios</b>. Many
invasions and conquests during this time with change of Rulers. Lineage from <b>
Mendes</b> founds <b>29<sup>th</sup> Dynasty</b>. <b>Nectanebo I</b> <b>re-conquers</b>
all of <b>Egypt</b>. And to finalize this era, <b>Alexander the Great</b> <b>invaded Egypt</b>
and Egypt falls into <b>control</b> of the <b>Greeks</b>; </font></span><b>
<span style="font-family: Courier New"><font size="3">Alexandria </font></span>
</b><span style="font-family: Courier New"><font size="3">becomes the <b>new</b> <b>
Capital</b>.</font></span></p>
<p class="MsoNormal" align="center" style="text-align: center"> </p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">GRAECO-ROMAN PERIOD
<i>c</i>. 332 BCAD 641</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><span style="font-size: 16pt">Alexandria & Beyond</span></b></font></p>
<p class="MsoNormal" align="center" style="text-align: center">
<font face="Courier New"><b><u>
<span style="text-decoration: none; font-size: 8.0pt"> </span></u></b></font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New"><b>Alexander the Great</b> had conquered Egypt along
with all of her glories. The <b>Macedonian</b>s were <b>ruling Egypt</b>, yet this was
a <b>welcomed occupation</b> as they had <b>driven</b> the <b>Persian</b> <b>invaders
</b>out of
Egypt which had bound them and <b>caused great decline</b>. <b>Alexandria</b> was a
great <b>Capital City</b>, housing the <b>Great Alexandria Library</b> that is
so famous for its <b>burning</b> to the ground during the <b>Roman</b> <b>invasion <i>c</i>.
30 BC</b>, somewhere near the reign of <b>Cleopatra VII</b>. Previous to the Roman
invasion, Egypt was ruled under the <b>Ptolemies</b>, a long lineage descended
from one of Alexanders great Generals. <b>Kings</b> assumed the role of <b>
Pharaoh</b> and this was an <b>era</b> of great <b>Temple</b> <b>building</b>.</font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="left">
</p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New">In <b>196 BC decree</b> commemorating <b>Ptolemy Vs</b>
<b>coronation</b>; as slab of <b>inscribed basalt</b> depicts this decree and
was later to be <b>found</b> by a <b>French soldier</b> named <b>Pierre Poushar</b>
in <b>1799</b>, <b>in Rosetta</b> a small village <b>near</b> the river
<b>Nile</b> and is
known as the <b>Rosetta Stone</b>. The <b>Temples</b> at <b>Dendera</b> show
magnificent <b>hieroglyphics</b> of this era of <b>occupation</b> with <b>Caesar</b>, <b>Mark
Antony</b> and <b>Cleopatra</b>.</font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
</p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="center">
<img border="0" src="EDenAt583.jpg" width="583" height="366" longdesc="Dendera Temple of Hathor Egypt ancient Egyptian timeline article published in Circular Times and photograph by Colette Dowell" alt="Dendera Temple of Hathor Egypt image ancient Egyptian timeline "></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="center">
</p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<b><font face="Courier New">D</font></b><font face="Courier New"><b>endera</b> is also known for the great <b>Temple of
Hathor </b>and the amazing <b>Ceiling Zodiac</b>. Beginning with the ruling
under <b>Rome</b> when <b>Octavian</b> <b>invaded Egypt</b> for the main purpose of her
rich grain. <b>Christianity</b> spread <b>through Egypt</b> during the time of <b>
Constantine</b>. <b>Greek</b> still remained the <b>official language</b> until the <b>Arabs</b>
<b>invaded</b> in <b>AD 641 </b>and <b>Islam</b> became the predominant <b>Religion</b>
and <b>Language</b>. However, <b>Christianity remained</b> and the influence of the <b>
Coptic Church</b>. Both the <b>Coptic Church</b> and <b>Islamic</b> or modern
day <b>Muslim</b> are <b>recognized</b> in <b>modern</b> day <b>Egypt</b> along with other
nationalities and faiths.</font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New"> </font></p>
<p class="MsoNormal" style="text-indent: 36.0pt" align="justify">
<font face="Courier New"><b>Cairo</b> is now the <b>Main Necropolis</b> and <b>
Capital of Egypt</b> located in the <b>Upper Land (Delta) of Egypt</b>. <b>Giza</b>
is a small town <b>next to Cairo</b>, where<span style="font-size: 14.0pt"> the </span>
<b>Great Pyramid</b> and the <b>Great Sphinx</b> are located next to the river
<b>Nile</b>. So here we are now modern Egypt!</font></p>
<p class="MsoNormal" align="center" style="text-align: left"> </p>
<p class="MsoNormal" align="center" style="text-align: left">
<font face="Courier New" size="3">Colette M. Dowell</font></p>
<p class="MsoNormal" align="center" style="text-align: left"> </p>
<p class="MsoNormal" align="center" style="text-align: left"><b>
<font face="Courier New" size="4">Bibliography</font></b></p>
<p class="MsoNormal" align="left"><font face="Courier New"><i>Ancient Egypt:
Kingdom of the Pharaohs</i>, R. Hamilton, Parrogon Publishing</font></p>
<p class="MsoNormal" align="left"><font face="Courier New"><i>British Museum
Dictionary of Ancient Egypt</i>, Ian Shaw & Paul Nicholson, BCA </font></p>
<p class="MsoNormal" align="left"><font face="Courier New"><i>Ancient Egypt: The
Great Discoveries</i>, Nicholas Reeves, Thames & Hudson</font></p>
<p class="MsoNormal" align="left"> </p>
<p class="MsoNormal" align="left"><font face="Courier New">Dr. Colette Dowell is
available for radio interviews and speaking engagements- tour guide to Egypt. <b>
<a href="mailto:cosmicgalas@gmail.com?subject=Radio Speaking Tour">
<font color="#A7110A">Contact for more information</font></a></b>. Thank you.</font></p>
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Intellectual, Scientific and Philosophical Studies</span></font></p>
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Ancient Egyptian Timeline Old-New Kingdom Colette Dowell
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Ancient Egyptian Timeline Old-New Kingdom timeline
in simple form to understand Pre Dynastic to New Kingdom, Upper and Lower Egypt
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**A
SURREALISTIC VIEW OF**
**ANCIENT
EGYPT'S TIMELINE**
**[by Dr. Colette M. Dowell](mailto:cosmicgalas@gmail.com?subject=From your Website)**
![Image of Sphinx body and face Valley Temple and Khafre Pyramid photograph by Colette Dowell](ESMTPbt700.jpg)
**Preface**
Many times I stumble on Egyptian jargon of
Pre-Dynastic this and which Dynasty that, Old Kingdom in Lower Egypt (Delta) vs.
New Kingdom in Upper Egypt, Ra, Isis, Horus, Akhenaten, Khufu or Khafre, or none
at all, Temple or Mastaba, this or that and so on and so forth. Hence, I decided
to make a simple timeline including a few Egyptian concepts and historical
venues. This little Egyptian timeline serves a simple purpose by keeping things
simple and if there is a need to complicate things a bit more, well at least
there is a guide and timeframe to go by that is not too overwhelming to
comprehend. I have bold typed key words to impress them in the mind as they seem
to be of importance to understand Egypts development through her most
controversial times. I hope this helps you too. Colette Dowell
**ANCIENT EGYPTIAN TIMELINE**
**Introduction**
There is evidence of human occupation
in the Land of Egypt *c*. 200,000 BC , being that of the Nomadic Hunter
Gatherer stage of human evolution. After the last **Ice Age *c*. 10,000 BC**,
**climatic change begins and temperate zones appear** allowing agriculture
possible due to the **Sun** and annual inundation of the river **Nile**,
where Villages and Central Communities begin to emerge. Boats were first made
from papyrus; secondary wood. The river **Nile** served as a **central trade route** for
exchange of gold, pottery and other cultural expressions that began to develop
and the era of the **Predynastic Period** of **Egypt *c*. 5500 BC
begins**. Egypts two separate kingdoms, **Lower Egypt** (Delta) and **Upper Egypt**, are relative in terms to the flow of the river Nile. **The
Early Dynastic Period of Egypt *c*. 3100 BC unifies Lower and Upper Egypt.**
The **Capital** **&** **Royal Court** are based in **Memphis**, and
**Abydos** is the **Main Necropolis**.
![Image of Nile River Egypt near Luxor photograph by Colette Dowell](ENileA566.JPG)
**Order From Chaos**
**PREDYNASTIC PERIOD *c*. 5500 BC*c*. 3100 BC**
Upper and Lower Egypt; Distinct Anatomical Differences;
Separate Gods evolve into assimilated Gods; **Sacred Symbols****Lotus &
Papyrus**. **Death-Rebirth Cycle** of **two great natural elements /
forces** = **Sun** and the **Nile**. **Afterlife and Funerary Rituals**Bodies
placed facing **WestSunset**. Earliest body preservationshrouded and laid
in desert sand. **Migrants** from **Nubia**, **Palestine** &
**Syria**. Migration to the North
of Egypt (Lower Egypt). **Hieroglyphs develop *c*. 3400 BC.**
**EARLY DYNASTIC PERIOD
*c*. 3100 BC*c*. 2686 BC**
**First and Second
Dynasties:**
**Narmer ** (**Menes**, possibly same person) **First Ruler** of **Dynastic Period. Scorpion ** One of the last Rulers of
this period. **Kingship** develops secular power over **Two Lands** and
identify themselves as an embodiment with Gods; **Horus**, the **Sun God Re**
and the **Son of Re**. **Capital** **&** **Royal Court**-**Memphis;**
**Abydos is Main Necropolis**. **Mastaba Tombs** built from **mudbrick**
and **Mortuary Temples** housed the Deceaseds ***ka*;** **a** **Spirit Force surviving death**. **Stelae** is an inscribed slab inside and
outside of Tombs and Temples depicting **information** of that particular **King** and **Deity** associated with him. First calendrical system based on
astronomical measurements and **Hieratic Script** developed.
**OLD KINGDOM *c*.
2686 BC*c*. 2181 BC**
**Third Sixth
Dynasties:**
Sophistication of Society and
**Pharaonic** era begins. Technology advances along with culture. **Imhotep**,
vizier to **King Djoser**, designs the **first Stepped Pyramid, *c*.
2650**, known as **Djosers Stepped Pyramid**, located in **Saqqara**,
constructed by stone and built by Egyptians who believed their **Afterlife**
was dependent on the glories of their **Kings Funerary Monument**; the **Pyramid**.
![Image of Valley Temple Khafre Pyramid Giza Egypt photograph by Colette Dowell](EMTKP320.jpg)
What we **visualize** as **True Pyramids** were
built in the **4th Dynasty** on the **Giza Plateau**. The first
of these, **The Great Pyramid**, supposedly was built by **Khufu**, the
**Second Pyramid-Khafre** and the **Third Pyramid-Menkaure**, near the **Great Sphinx**, whose date of construction deemed by **Orthodox
Egyptologists** view is that of ***c*. Khafre**.
The **Nemes Headcloth** and **ceremonial false beard** was part of the **Royal regalia**. Even **Isis** was known to wear a **beard** to **portray** her as a **Pharaoh**. Boats played a significant role in the
funerary beliefs. The **Sun God Re** was believed to travel through the skies
and the **Underworld** by the **Solar Barque**, (vessel-boat) and after
death the **King** was thought to embark on a **similar journey**. 1200
pieces of wood, material used for a vessel was uncovered in **Giza** in **1954**,
taking 10 years to reconstruct what is possibly **Khufus funerary Barque**
or vessel. The **traveling across** the **Nile from East to West** was
ritualistic as the **Sun rising in the East and setting in the West**. For
this reason the **causeways** of **Mortuary Temples** began being situated on the
**Eastern Face** of the **Pyramid** of Kings, **leading to the riverbanks** of the river
**Nile**. These causeways were also used for transporting materials across the Nile.
**FIRST INTERMEDIATE
PERIOD *c.* 2181 BC*c*. 2055 BC**
**Seventh Eleventh
Dynasties**
Long periods of instability due to provincial rules
warring for control. Political upheaval and decline in economics, famine
prevails. There was a **rise** in the **prominence** of **Osiris** during this time, most
likely due to the **need of survival** and the **belief of resurrection**; as of this
time all of Egypt, both **Upper** and **Lower** were in a state of **despair**. The **Rulers** who originated from **Herakleopolis** during the **9th
Dynasty gained control** and were in conflict with **Theban Princes**,
later who **gained** either the diplomatic or military **victory** over the
**Herakleopolis Rulers.** **Mentuhotep II** founded the **11th
Dynasty** **creating order** once again and **prosperity** was finally
**restored to
Egypt**, thus the **Osirian Legend** performed a remarkable trend of belief and
following. **The Royal Court** was moved to **Thebes** during this time.
**MIDDLE KINGDOM *c*.
2055 BC*c*. 1650 BC**
**Eleventh Fourteenth
Dynasties**
The **second great era** of **Egyp**t with the **Golden Age**
of prosperity and achievement. **Amenemhat I** was founder of the **12th
Dynasty** and **Itjtawy** becomes the new **Capital** of **Egypt**.
**Karnak** was established through **Osiris** and **Amun** was
pre-eminent in this era. **Abydos** was the most important pilgrim **center** of
**trade** and **political** standing. **Later** another **decline** set into Egypt as the
**migrating** **Middle Easterners**, the **Hyksos** **invade** and **settle**
in **Egypt**. This era **began** the age of **Bronze** smelting.
**![Image of Hieroglyphics Hieroglyphs honey bees and flyiing wasps hornets Karnak Temple in Luxor Egypt photograph by Colette Dowell](EKnkHaT397.JPG)**
**SECOND INTERMEDIATE
PERIOD *c*. 1650 BC*c*. 1550 BC**
**Fifteenth
Seventeenth Dynasties**
The **Hyksos** ruled and established themselves with
a **Capital** in **Avaris** in the **Delta** (**Upper Egypt**),
while other **Indigenous Rulers** held **other territories**. **Egypt** began
to **decline** again in central **power**. However the **Hyksos** did bring in a
**new era** for
Egypt as they brought in **arts**, and **culture**. This was the **first** era to see
the **chariot** and advancement in **military technology**. The **horse**, **lute** and **lyre** came in the **16th Dynasty**. During the
**17th
Dynasty** the **Hyksos** ruled from **Thebes**. However there was so much
tension and decline of power the **Theban Princes** **conquered** the **Hyksos** so
once again **Egypt** was in the **hands** of her **native** peoples. The **18th
Dynasty** was founded under **Ahmose I**.
**NEW KINGDOM *c*.
1550 BC*c*. 1070 BC**
**Eighteenth Twentieth
Dynasties**
**Theban God Amun** was attributed to the **new era of
Egypt** and prosperity **after** the expulsion of the **Hyksos**. **Amun synchronizes
with Re** and **Amun-Re** was now the **Eminent Deity**. You see much of
**Amun Re** in the **Karnak** **Temple** as well as that of **Luxor**
and the surrounding great **Temples** built in the times circumscribing these
three dynasties. **Tuthmosis III** is Egypts greatest **Warrior King**
and expansion with **annexing** of **Nubia**, **Palestine** and **Syria**. The **Solar Deity Aten**, becomes a very **popular cult** under the
ruling of **Amenhotep IV**, who proscribed all other Gods.
![Image of Rameses III Luxor Temple Luxor Egypt photograph by Colette Dowell](ELxStAZ604.JPG)
**Amenhotep IV changes his name to Akhenaten** and
moves the **Royal Court** to modern day area of **Tell el Amarna**. Later
**Tutankhamun** **restored** the **traditional pantheon**. **Rameses I** founded
the **19th Dynasty** and now **Qantir** is new **Capital**.
Many **invasions** by **Libyans**, **Nubians** and others to **create chaos**;
**Egypt prevails**. **Valley of the Kings** at **Thebes** is established as
the **Royal Necropolis**. The **Ramessid Era** had seen tremendous
**hardships** and civil and economic **unrest** while the **Royal Authority declined**.
The **Cult of Osiris & Isis** became most prominent in the **New Kingdom, *c*. 1550 BC 1070 BC**.
**[![Image Egyptian antique jewelry gold silver pearls beads Collectors handmade and custom by Colette Dowell for Sabu Designs all fine costume jewelry inspired by world travels and museums native shops European jewelry castlesin Europe and Russia](SABU%20c120.JPG)](Jewelry%20Egyptian%20Antique%20Maya%20Inca%20Far%20East%20India%20Native%20American%20European%20Africa%20Collector%20Handmade%20Silver%20Gold%20Motif.htm)THIRD INTERMEDIATE
PERIOD *c*. 1070 BC*c*. 747 BC**
**Twentyfirst
Twentyfourth Dynasties**
**Smendes** founded **21st Dynasty**
and **Tanis** in the **Delta** is ruling **Capital**. The **High
Priests** of **Amun rule Southern Egypt from Thebes**. Later **two lineages
marry** and blend, helping the rivalry of **Lower and Upper Egypt**. **Egypt** is
**united**
once again while being ruled under concurrent powers. The dominant power in the
**Delta** was that of **Sais**. **Piy** was **Ruler** of the **Southern Kingdom** and **Napata** is **Capital**. New age of **Iron**
working.
**LATE PERIOD *c*.
747 BC*c*. 332 BC**
**Twentyfifth -
Thirtieth Dynasties**
**Shabaqo**
from **Napata**
conquered the whole of Egypt and founded the **25th Dynasty**. **Assyrians** **invaded** and established **Saite Lineage** to **rule Egypt**.
**Babylonia**
rises to **power** and **wipes out** the **Assyrians**, then **Persia**
**invades** the **Assyrians** as **dominant power** and the **26th
Dynasty** is established. The **Egyptian Natives** however finally **expel**
the **Persians** by the **Saite** leader known as **Amyrtaios**. Many
invasions and conquests during this time with change of Rulers. Lineage from **Mendes** founds **29th Dynasty**. **Nectanebo I** **re-conquers**
all of **Egypt**. And to finalize this era, **Alexander the Great** **invaded Egypt**
and Egypt falls into **control** of the **Greeks**; **Alexandria**becomes the **new** **Capital**.
**GRAECO-ROMAN PERIOD
*c*. 332 BCAD 641**
**Alexandria & Beyond**
**Alexander the Great** had conquered Egypt along
with all of her glories. The **Macedonian**s were **ruling Egypt**, yet this was
a **welcomed occupation** as they had **driven** the **Persian** **invaders**out of
Egypt which had bound them and **caused great decline**. **Alexandria** was a
great **Capital City**, housing the **Great Alexandria Library** that is
so famous for its **burning** to the ground during the **Roman** **invasion *c*.
30 BC**, somewhere near the reign of **Cleopatra VII**. Previous to the Roman
invasion, Egypt was ruled under the **Ptolemies**, a long lineage descended
from one of Alexanders great Generals. **Kings** assumed the role of **Pharaoh** and this was an **era** of great **Temple** **building**.
In **196 BC decree** commemorating **Ptolemy Vs**
**coronation**; as slab of **inscribed basalt** depicts this decree and
was later to be **found** by a **French soldier** named **Pierre Poushar**
in **1799**, **in Rosetta** a small village **near** the river
**Nile** and is
known as the **Rosetta Stone**. The **Temples** at **Dendera** show
magnificent **hieroglyphics** of this era of **occupation** with **Caesar**, **Mark
Antony** and **Cleopatra**.
![Dendera Temple of Hathor Egypt image ancient Egyptian timeline ](EDenAt583.jpg)
**D****endera** is also known for the great **Temple of
Hathor** and the amazing **Ceiling Zodiac**. Beginning with the ruling
under **Rome** when **Octavian** **invaded Egypt** for the main purpose of her
rich grain. **Christianity** spread **through Egypt** during the time of **Constantine**. **Greek** still remained the **official language** until the **Arabs**
**invaded** in **AD 641** and **Islam** became the predominant **Religion**
and **Language**. However, **Christianity remained** and the influence of the **Coptic Church**. Both the **Coptic Church** and **Islamic** or modern
day **Muslim** are **recognized** in **modern** day **Egypt** along with other
nationalities and faiths.
**Cairo** is now the **Main Necropolis** and **Capital of Egypt** located in the **Upper Land (Delta) of Egypt**. **Giza**
is a small town **next to Cairo**, where the
**Great Pyramid** and the **Great Sphinx** are located next to the river
**Nile**. So here we are now modern Egypt!
Colette M. Dowell
**Bibliography**
*Ancient Egypt:
Kingdom of the Pharaohs*, R. Hamilton, Parrogon Publishing
*British Museum
Dictionary of Ancient Egypt*, Ian Shaw & Paul Nicholson, BCA
*Ancient Egypt: The
Great Discoveries*, Nicholas Reeves, Thames & Hudson
Dr. Colette Dowell is
available for radio interviews and speaking engagements- tour guide to Egypt. **[Contact for more information](mailto:cosmicgalas@gmail.com?subject=Radio Speaking Tour)**. Thank you.
[Look at what Sabu the Great Nubian is doing now!](Ancient%20Egyptian%20Timeline%20Upper%20Lower%20Egypt%20Colette%20Dowell%20CT.htm)
*Behold the great treasures I
bring to you!*
[![](SF182.JPG)](Jewelry%20Egyptian%20Antique%20Maya%20Inca%20Far%20East%20India%20Native%20American%20European%20Africa%20Collector%20Handmade%20Silver%20Gold%20Motif.htm)
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*An International Networking Educational Institute*
Intellectual, Scientific and Philosophical Studies
**Copyright © 1995, 2005, 2006, 2007**
**[Dr. Colette M. Dowell, N.D.](mailto:cosmicgalas@gmail.com?subject=From your Website)**
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<!--<a href="http://bungus.net"><img style="width: 142.6px; height: 53.3px;" src="img/bungusnet_inactive.gif" onmouseover="this.src='img/bungusnet_active.gif';" onmouseout="this.src='img/bungusnet_inactive.gif';" hspace="25" /></a>-->
</center>
<br/>
<br/>
<br/>
<center>
<h3> Jack into the SKUMSOFT network:</h3>
<p> Server: irc.libera.chat | Channel: #skumsoft.ltd <p>
<p> <a style="color:white;" href="https://web.libera.chat/gamja/?channels=#skumsoft.ltd">[Click Here for IRC Webchat]</a><p>
<p> Dial into the SKUMSOFT <a style="color:white;" href="hotline.html">Hotline</a>! </p>
<h3> U <a style="color:white;" href="img/bugmode.jpg">bug'n</a>?? Hop n2 Quake 3 Arena with us Sometime: </h3>
<p> <a style="color:white;" href="img/quakers.gif">We play often</a>! Smack skumsoft.ltd in ur client! </p>
<a href="https://skumsoft.ltd/skumup/"><img style="position: fixed; top: 0px; right: 0px;" src="/slimenet/img/null.png"></a>
</center>
</body>
</html>
|
body {
background-image: url("img/blackmarble.jpg");
background-repeat: repeat;
}
SKUMSOFT
![](img/skumsoft.png)
![](img/enter.gif)
[![](img/slime-net.png)](slimenet/index.html)
### Jack into the SKUMSOFT network:
Server: irc.libera.chat | Channel: #skumsoft.ltd
[[Click Here for IRC Webchat]](https://web.libera.chat/gamja/?channels=#skumsoft.ltd)
Dial into the SKUMSOFT [Hotline](hotline.html)!
### U [bug'n](img/bugmode.jpg)?? Hop n2 Quake 3 Arena with us Sometime:
[We play often](img/quakers.gif)! Smack skumsoft.ltd in ur client!
[![](/slimenet/img/null.png)](https://skumsoft.ltd/skumup/)
| https://skumsoft.ltd/ |
<!DOCTYPE html>
<html lang=en>
<head>
<meta charset=utf-8>
<link href="holidays/christmas/christmas.css" type="text/css" rel="stylesheet" media="all">
<title>My increasingly adequate website</title>
<meta name="description" content="The homepage of my increasingly adequate website.">
<meta name="referrer" content="no-referrer">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
</head>
<body>
<header>
<h1>My increasingly adequate website</h1>
</header>
<main>
<p>
Welcome to my increasingly adequate website.
I used to greet site visitors with this: "You won't find much here yet, and maybe you never will."
By now it's a safe bet that you'll never find anything particularly important here.
</p>
<p>
Still, it's nice to have a bit of cyberspace to call one's own.
I'm using this space to say a little bit about computers, computer games, politics, and a few other things I'm interested in.
You'll notice that this site has an archaic appearance.
This is intentional.
The old-fashioned style <a href="images/screenshots/macwww.png">works well even in ancient browsers</a>, looks adequate, and is easy for me to author.
The style is also an homage to the old days of the web, when each person had complete control over what they could put online and how it was ordered and displayed.
Now, so many webpages are made when some corporate database spews out a few fields onto a cookie-cutter webpage (e.g., Facebook).
</p>
<img src="holidays/christmas/christmas_tree.gif" alt="Christmas tree">
<h2>Pages on this site</h2>
<nav>
<ul>
<li><a href="kerrbib.html">A bibliography of the Charles H. Kerr Company, 1899-1928</a></li>
<li><a href="gameslists.html">The best lists of the best games</a></li>
<li><a href="christmas.html">A Cylindrical Christmas: Christmas songs from 1898-1917</a></li>
<li class="new"><a href="commleft_spa.html">The Communist Left in the US: "Comrades Across the Ocean:" The German-Dutch and American socialist lefts, 1912-1917</a></li>
<li class="new"><a href="commleft_german.html">The Communist Left in the US: The Groups of Council Communists and the Spanish Civil War</a></li>
<li><a href="cmus.html">cmus, a really quick guide</a></li>
<li><a href="minnesotaelections.html">Historic presidential election results by county for Minnesota</a></li>
<li><a href="albums.html">My favorite albums by year</a></li>
<li><a href="macppc.html">OpenBSD 6.5 on a 1999 iMac G3 (iMac,1)</a></li>
<li><a href="panzerstorm.html"><cite>Panzer General</cite>, <cite>Iron Storm</cite>, and a momentous decision</a></li>
<li><a href="statecapitalism.html">Preliminary notes on the state and 19th century capitalism</a></li>
<li><a href="profitsystem.html">The profit system: every day another disaster</a></li>
<li><a href="recipes.html">Recipes I like</a></li>
<li><a href="lovestory.html">Review of <cite>Capitalism: A Love Story</cite></a></li>
<li><a href="manandfighter.html">Review of <cite>Karl Marx: Man and Fighter</cite></a></li>
<li><a href="greatfinancialcrisis.html">Review of <cite>The Great Financial Crisis: Causes and Consequences</cite></a></li>
<li><a href="monsteratourdoor.html">Review of <cite>The Monster at Our Door: the Global Threat of Avian Flu</cite></a></li>
<li><a href="mad.html">Things that make me mad</a></li>
<li><a href="unfuck.html">An "Unfuck Your Habitat"-like program for Linux/Unix/macOS</a></li>
<li><a href="gis.html">Using GIS to track the strength of the Socialist Party of America in Minnesota</a></li>
<li><a href="voting.html">Voting: not just pointless, but harmful!</a></li>
</ul>
</nav>
<h2>My other sites</h2>
<nav>
<ul>
<li><a href="https://blog.increasinglyadequate.com">My blog</a></li>
<li><a href="https://www.flickr.com/photos/vofuth">My Flickr</a></li>
</ul>
</nav>
</main>
<footer>
<p>
To the extent possible under law, this author has waived all copyright and related or neighboring rights to this website.
This work is published from United States.
Page updated <time>2023-12-02</time>.
Send email to schalken at warpmail dot net.
</p>
</footer>
</body>
</html>
|
My increasingly adequate website
# My increasingly adequate website
Welcome to my increasingly adequate website.
I used to greet site visitors with this: "You won't find much here yet, and maybe you never will."
By now it's a safe bet that you'll never find anything particularly important here.
Still, it's nice to have a bit of cyberspace to call one's own.
I'm using this space to say a little bit about computers, computer games, politics, and a few other things I'm interested in.
You'll notice that this site has an archaic appearance.
This is intentional.
The old-fashioned style [works well even in ancient browsers](images/screenshots/macwww.png), looks adequate, and is easy for me to author.
The style is also an homage to the old days of the web, when each person had complete control over what they could put online and how it was ordered and displayed.
Now, so many webpages are made when some corporate database spews out a few fields onto a cookie-cutter webpage (e.g., Facebook).
![Christmas tree](holidays/christmas/christmas_tree.gif)
## Pages on this site
* [A bibliography of the Charles H. Kerr Company, 1899-1928](kerrbib.html)
* [The best lists of the best games](gameslists.html)
* [A Cylindrical Christmas: Christmas songs from 1898-1917](christmas.html)
* [The Communist Left in the US: "Comrades Across the Ocean:" The German-Dutch and American socialist lefts, 1912-1917](commleft_spa.html)
* [The Communist Left in the US: The Groups of Council Communists and the Spanish Civil War](commleft_german.html)
* [cmus, a really quick guide](cmus.html)
* [Historic presidential election results by county for Minnesota](minnesotaelections.html)
* [My favorite albums by year](albums.html)
* [OpenBSD 6.5 on a 1999 iMac G3 (iMac,1)](macppc.html)
* [Panzer General, Iron Storm, and a momentous decision](panzerstorm.html)
* [Preliminary notes on the state and 19th century capitalism](statecapitalism.html)
* [The profit system: every day another disaster](profitsystem.html)
* [Recipes I like](recipes.html)
* [Review of Capitalism: A Love Story](lovestory.html)
* [Review of Karl Marx: Man and Fighter](manandfighter.html)
* [Review of The Great Financial Crisis: Causes and Consequences](greatfinancialcrisis.html)
* [Review of The Monster at Our Door: the Global Threat of Avian Flu](monsteratourdoor.html)
* [Things that make me mad](mad.html)
* [An "Unfuck Your Habitat"-like program for Linux/Unix/macOS](unfuck.html)
* [Using GIS to track the strength of the Socialist Party of America in Minnesota](gis.html)
* [Voting: not just pointless, but harmful!](voting.html)
## My other sites
* [My blog](https://blog.increasinglyadequate.com)
* [My Flickr](https://www.flickr.com/photos/vofuth)
To the extent possible under law, this author has waived all copyright and related or neighboring rights to this website.
This work is published from United States.
Page updated 2023-12-02.
Send email to schalken at warpmail dot net.
| https://www.increasinglyadequate.com/ |
<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="utf-8">
<meta name="author" content="mark3tchup">
<meta name="description" content="Welcome to mark3tchup's corner on the web.">
<meta name="keywords" content="mark3tchup,Retro,Books,Writing,Programming,Art">
<meta name="viewport" content="width=device-width, initial-scale=1">
<link rel="icon" type="image/png" sizes="32x32" href="https://mark3tchup.tilde.cafe/favicon.png">
<link rel="me" href="https://tilde.zone/@mark3tchup">
<title>The Entrance</title>
</head>
<body>
<hgroup>
<h1>A little corner on the web.</h1>
<p><samp>> You have arrived at a safe and quiet spot.</samp></p>
<p><samp>> <strong>The complicated problems of the real world have no place here.</strong></samp></p>
</hgroup>
<hr>
<main>
<p>Welcome, explorer! I, <em>mark3tchup</em>, am glad to have you come to this haven away from noisy civilization.</p>
<h2>What can you find here?</h2>
<dl>
<dt><a href="https://mark3tchup.tilde.cafe/hall/">The Exhibition Hall</a></dt>
<dd>An incipient collection of ASCII and Unicode "art".</dd>
<dt><a href="https://mark3tchup.tilde.cafe/planetarium.html">The Planetarium</a></dt>
<dd>A selection of resources (sites, essays, books) from universal literature and the World Wide Web.</dd>
<dt><a href="https://mark3tchup.tilde.cafe/scrapbook.html">The Scrapbook</a></dt>
<dd>A historical record of updates to this site.</dd>
<dt><a href="https://mark3tchup.tilde.cafe/about.html">Trivial Thoughts</a></dt>
<dd>About me, this site, and the Great Question of Life, Universe and Everything.</dd>
</dl>
<p>That's all. Please enjoy your stay :-)</p>
</main>
<footer>
<small>Except where otherwise noted, content on this site is licensed under a <a rel="license" href="https://creativecommons.org/licenses/by-sa/4.0/">Creative Commons Attribution-ShareAlike 4.0 International License</a>.</small>
<hr>
<a href="https://mark3tchup.tilde.cafe/"><img alt="mark3tchup's corner on the web" src="https://mark3tchup.tilde.cafe/images/buttons/site.png" loading="lazy"></a>
<img alt="Made on GNU/Linux" src="https://mark3tchup.tilde.cafe/images/buttons/gnu-linux.png" loading="lazy">
<a href="https://neovim.io/"><img alt="Made with Neovim" src="https://mark3tchup.tilde.cafe/images/buttons/neovim.png" loading="lazy"></a>
<img alt="Completely hand-coded!" src="https://mark3tchup.tilde.cafe/images/buttons/hand-coded.gif" loading="lazy">
<img alt="Best viewed on a real computer" src="https://mark3tchup.tilde.cafe/images/buttons/computer.jpg" loading="lazy">
<a rel="license" href="https://creativecommons.org/licenses/by-sa/4.0/"><img alt="Creative Commons License" src="https://mark3tchup.tilde.cafe/images/buttons/cc-by-sa.png" loading="lazy"></a>
</footer>
</body>
</html>
|
The Entrance
# A little corner on the web.
`> You have arrived at a safe and quiet spot.`
`> **The complicated problems of the real world have no place here.**`
---
Welcome, explorer! I, *mark3tchup*, am glad to have you come to this haven away from noisy civilization.
## What can you find here?
[The Exhibition Hall](https://mark3tchup.tilde.cafe/hall/)
An incipient collection of ASCII and Unicode "art".
[The Planetarium](https://mark3tchup.tilde.cafe/planetarium.html)
A selection of resources (sites, essays, books) from universal literature and the World Wide Web.
[The Scrapbook](https://mark3tchup.tilde.cafe/scrapbook.html)
A historical record of updates to this site.
[Trivial Thoughts](https://mark3tchup.tilde.cafe/about.html)
About me, this site, and the Great Question of Life, Universe and Everything.
That's all. Please enjoy your stay :-)
Except where otherwise noted, content on this site is licensed under a [Creative Commons Attribution-ShareAlike 4.0 International License](https://creativecommons.org/licenses/by-sa/4.0/).
---
[![mark3tchup's corner on the web](https://mark3tchup.tilde.cafe/images/buttons/site.png)](https://mark3tchup.tilde.cafe/)
![Made on GNU/Linux](https://mark3tchup.tilde.cafe/images/buttons/gnu-linux.png)
[![Made with Neovim](https://mark3tchup.tilde.cafe/images/buttons/neovim.png)](https://neovim.io/)
![Completely hand-coded!](https://mark3tchup.tilde.cafe/images/buttons/hand-coded.gif)
![Best viewed on a real computer](https://mark3tchup.tilde.cafe/images/buttons/computer.jpg)
[![Creative Commons License](https://mark3tchup.tilde.cafe/images/buttons/cc-by-sa.png)](https://creativecommons.org/licenses/by-sa/4.0/)
| https://mark3tchup.tilde.cafe/ |
<!DOCTYPE html>
<html>
<head>
<TITLE>Molossian Navy</TITLE>
<meta name="viewport" content="width=device-width, initial-scale=1">
<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/4.7.0/css/font-awesome.min.css">
<BODY bgcolor=#FFFFFF link="#FF0000" vlink="#FF0000" alink="#FF0000">
<style>
body {
font-family: Arial, Helvetica, sans-serif;
}
.navbar {
overflow: hidden;
background-color: #333;
}
.navbar a {
float: left;
font-size: 12px;
color: white;
text-align: center;
padding: 14px 16px;
text-decoration: none;
}
.dropdown {
float: left;
overflow: hidden;
}
.dropdown .dropbtn {
font-size: 12px;
border: none;
outline: none;
color: white;
padding: 14px 16px;
background-color: black;
font-family: inherit;
margin: 0;
}
.navbar a:hover, .dropdown:hover .dropbtn {
background-color: red;
}
.dropdown-content {
display: none;
position: absolute;
background-color: #f9f9f9;
min-width: 160px;
box-shadow: 0px 8px 16px 0px rgba(0,0,0,0.2);
z-index: 1;
}
.dropdown-content a {
float: none;
color: black;
padding: 12px 16px;
text-decoration: none;
display: block;
text-align: left;
}
.dropdown-content a:hover {
background-color: #ddd;
}
.dropdown:hover .dropdown-content {
display: block;
}
</style>
</head>
<body>
<CENTER><A HREF="/index.html"><IMG SRC="/pictures/redbanner.jpg"></A>
<IMG SRC="/navy/navytitle2.jpg">
<CENTER>
<span style="display:inline-block; vertical-align:middle">
<div class="navbar">
<a href="/navy/vessels.html">Our Vessels</a>
<div class="dropdown">
<button class="dropbtn">Naval Missions
<i class="fa fa-caret-down"></i>
</button>
<div class="dropdown-content">
<a href="/navy/railroadtracks.html">Voyage to the Sunken Railroad Tracks</a>
<a href="/navy/monterey.html">The Navy Visits Monterey Bay</a>
<a href="/navy/magnet.html">Molossia's UMD</a>
<a href="/navy/rocketisland.html">Voyage To Rocket Island</a>
<a href="/navy/border.html">Voyage Across The Border</a>
<a href="/navy/scripps.html">Voyage Through Scripps Lagoon</a>
<a href="/navy/waterbug.html">Voyages Of The Waterbug</a>
<a href="/navy/lakeforest.html">Voyage To The Mysterious Island</a>
<a href="/navy/tallac.html">Voyage To Tallac Point</a>
<a href="/navy/bonsai.html">The Bonsai Rock Voyage</a>
<a href="/navy/tidepools.html">The Molossian Navy Coastal Study</a>
<a href="/navy/washoelake.html">The Washoe Lake Voyage</a>
<a href="/navy/caverock2.html">Return To Cave Rock</a>
<a href="/navy/donner4.html">Return To Donner Lake</a>
<a href="/navy/caverock.html">The Cave Rock Harbor Expedition</a>
<a href="/navy/lakes.html">The Mountain Lakes Mission</a>
<a href="/navy/ice.html">The Voyage Under The Ice</a>
<a href="/navy/tahoe.html">The Lake Tahoe Voyages</a>
<a href="/navy/tahoe2.html">Lake Tahoe Naval Mission</a>
<a href="/navy/seahorse.html">Seahorse Diving Bell Mission</a>
<a href="/navy/manta1.html">Manta USV Mission</a>
<a href="/navy/donner2.html">The Joint Vikesland-Molossia Naval Mission</a>
<a href="/navy/island2.html">The Emerald Bay Mission</a>
<a href="/navy/beach.html">Pacific Ocean Odyssey</a>
<a href="http://www.youtube.com/watch?v=hg2WORYOkzQ">Maiden Voyage Of The Bandicoot And Platypus</a>
<a href="/navy/lake.html">The Donner Lake Mission</a>
<a href="/navy/island.html">Sandpiper Island Mission</a>
</div>
</div>
<div class="dropdown">
<button class="dropbtn">Weapons
<i class="fa fa-caret-down"></i>
</button>
<div class="dropdown-content">
<a href="/navy/tunacannon.html">The Tuna Cannon</a>
<a href="/navy/rocketcannon.html">The RC1 Rocket Cannon</a>
<a href="/navy/torpedo.html">The Great Rocket Torpedo Project</a>
<a href="/navy/panjandrum.html">The Great Panjandrum</a>
</div>
</div>
<a href="/navy/navalinfantry.html">Molossian Naval Infantry</a>
<a href="/navy/officers.html">Honorary Commissioned Officers</a>
<A HREF="/war/index.html">Republic Of Molossia War Office</A>
</div>
</span>
</CENTER>
<CENTER>
<FONT SIZE="-1" COLOR="#000000" FACE="Arial">
</FONT>
</center>
<BR><BR>
<FONT SIZE="-1" FACE="Arial">
We tried having an Army, but the US Olympic Committee used it against us. We tried having an Air Force, but the plane never flew, and anyway it was too small to fit anyone inside. So, here in the depths of the desert, we have created the Molossian Navy. Yes, the Navy. And we even have five boats (see <a href="/navy/vessels.html">Our Vessels</a>).<BR>
<BR>
Our goal with the Molossian Navy is to explore those watery places that dot the western landscape like gems in the sand. There are actually quite a few lakes and reservoirs through the western desert, and we have set our sights to explore as many as possible. In addition, our Navy stands ready to defend Molossia whenever necessary, through the means of our valiant Naval Infantry.<BR><BR>
<BR>
<CENTER><A HREF="/pictures/navymonument2.jpg"><IMG SRC="/pictures/navymonument2sm.jpg"><BR>
<FONT SIZE="-1" FACE="Arial">The Molossian Navy Monument</FONT></A></center>
</FONT>
</body>
</html>
|
Molossian Navy
body {
font-family: Arial, Helvetica, sans-serif;
}
.navbar {
overflow: hidden;
background-color: #333;
}
.navbar a {
float: left;
font-size: 12px;
color: white;
text-align: center;
padding: 14px 16px;
text-decoration: none;
}
.dropdown {
float: left;
overflow: hidden;
}
.dropdown .dropbtn {
font-size: 12px;
border: none;
outline: none;
color: white;
padding: 14px 16px;
background-color: black;
font-family: inherit;
margin: 0;
}
.navbar a:hover, .dropdown:hover .dropbtn {
background-color: red;
}
.dropdown-content {
display: none;
position: absolute;
background-color: #f9f9f9;
min-width: 160px;
box-shadow: 0px 8px 16px 0px rgba(0,0,0,0.2);
z-index: 1;
}
.dropdown-content a {
float: none;
color: black;
padding: 12px 16px;
text-decoration: none;
display: block;
text-align: left;
}
.dropdown-content a:hover {
background-color: #ddd;
}
.dropdown:hover .dropdown-content {
display: block;
}
[![](/pictures/redbanner.jpg)](/index.html)
![](/navy/navytitle2.jpg)
[Our Vessels](/navy/vessels.html)
Naval Missions
[Voyage to the Sunken Railroad Tracks](/navy/railroadtracks.html)
[The Navy Visits Monterey Bay](/navy/monterey.html)
[Molossia's UMD](/navy/magnet.html)
[Voyage To Rocket Island](/navy/rocketisland.html)
[Voyage Across The Border](/navy/border.html)
[Voyage Through Scripps Lagoon](/navy/scripps.html)
[Voyages Of The Waterbug](/navy/waterbug.html)
[Voyage To The Mysterious Island](/navy/lakeforest.html)
[Voyage To Tallac Point](/navy/tallac.html)
[The Bonsai Rock Voyage](/navy/bonsai.html)
[The Molossian Navy Coastal Study](/navy/tidepools.html)
[The Washoe Lake Voyage](/navy/washoelake.html)
[Return To Cave Rock](/navy/caverock2.html)
[Return To Donner Lake](/navy/donner4.html)
[The Cave Rock Harbor Expedition](/navy/caverock.html)
[The Mountain Lakes Mission](/navy/lakes.html)
[The Voyage Under The Ice](/navy/ice.html)
[The Lake Tahoe Voyages](/navy/tahoe.html)
[Lake Tahoe Naval Mission](/navy/tahoe2.html)
[Seahorse Diving Bell Mission](/navy/seahorse.html)
[Manta USV Mission](/navy/manta1.html)
[The Joint Vikesland-Molossia Naval Mission](/navy/donner2.html)
[The Emerald Bay Mission](/navy/island2.html)
[Pacific Ocean Odyssey](/navy/beach.html)
[Maiden Voyage Of The Bandicoot And Platypus](http://www.youtube.com/watch?v=hg2WORYOkzQ)
[The Donner Lake Mission](/navy/lake.html)
[Sandpiper Island Mission](/navy/island.html)
Weapons
[The Tuna Cannon](/navy/tunacannon.html)
[The RC1 Rocket Cannon](/navy/rocketcannon.html)
[The Great Rocket Torpedo Project](/navy/torpedo.html)
[The Great Panjandrum](/navy/panjandrum.html)
[Molossian Naval Infantry](/navy/navalinfantry.html)
[Honorary Commissioned Officers](/navy/officers.html)
[Republic Of Molossia War Office](/war/index.html)
We tried having an Army, but the US Olympic Committee used it against us. We tried having an Air Force, but the plane never flew, and anyway it was too small to fit anyone inside. So, here in the depths of the desert, we have created the Molossian Navy. Yes, the Navy. And we even have five boats (see [Our Vessels](/navy/vessels.html)).
Our goal with the Molossian Navy is to explore those watery places that dot the western landscape like gems in the sand. There are actually quite a few lakes and reservoirs through the western desert, and we have set our sights to explore as many as possible. In addition, our Navy stands ready to defend Molossia whenever necessary, through the means of our valiant Naval Infantry.
[![](/pictures/navymonument2sm.jpg)
The Molossian Navy Monument](/pictures/navymonument2.jpg)
| http://www.molossia.org/navy/ |
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<META NAME="Description" CONTENT="Animation World Magazine, issue 1.12, March 1997, Children and Animation">
<TITLE>The Thief And The Cobbler</TITLE>
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<BLOCKQUOTE>
<P ALIGN=CENTER><FONT SIZE=-2><A HREF="http://www.awn.com/mag">Animation
World Magazine</A>, Issue 1.12, March 1997<BR>
</FONT><HR></P>
<H1 ALIGN=CENTER><FONT COLOR="#000000">The Thief And The Cobbler</FONT></H1>
<P ALIGN=RIGHT><FONT COLOR="#000000" SIZE=+1>by Alex Williams</FONT></P>
<P><B><I><FONT COLOR="#000000">Editor's Note:</FONT></I><FONT COLOR="#000000">
In August 1995, a film titled </FONT></B><FONT COLOR="#000000">Arabian
Knights<I> briefly appeared in American movie houses, hardly making a dent
in the box office. Nevertheless, many in the animation community started
to realize that this was no ordinary film, but rather a film assembled
from the ruins of Richard Williams' magnum opus, </I>The Thief and the
Cobbler,<I> which has now been released to the home video under its original
title. While </I>Animation World Magazine<I> usually does not like to review
films in their video version after they have been shown theatrically, we
thought it would be interesting to have Richard Williams' son Alex take
a gander at this version, which he had not seen before, and give us his
reactions; some of my own comments on the film can be found in this issue's
</I></FONT><A HREF="edito1.12.html">Editor's Notebook.</A><BR>
<BR>
<IMG SRC="../images/williams02.gif" WIDTH="216" HEIGHT="143" ALIGN="LEFT"
NATURALSIZEFLAG="3" ALT="The Cobbler and The Princess" BORDER="1"><FONT
COLOR="#000000" SIZE=-2>The Cobbler and The Princess</FONT></P>
<P><I><FONT COLOR="#000000">The Thief and the Cobbler</FONT></I><FONT COLOR="#000000">
was to have been the greatest animated film ever made, the culmination
of the a lifetime's work by master animator Richard Williams. Based on
the art of the Middle East, and in particular on the miniatures produced
in Safavid Persia circa 1500, the film was at least 30 Years in the making,
and became a legend in the animation industry.<BR>
<BR>
The version released on video by Miramax, described as "a musically-charged
animated epic created by Richard Williams, the Oscar winning animator of
<I>Who Framed Roger Rabbit,</I>" is a degraded version of Williams'
masterpiece, hardly worthy of the name it bears. lt is the same film formerly
released theatrically as <I>Arabian Knight,</I> a work of such startling
bad taste that it discredits all who were involved in its completion. The
film is more or less unwatchable, a collage of laughably third rate animation
interspersed with scenes of remarkable beauty, leftovers from the original
cut. Worst of all are the three song sequences, banal and depressingly
mediocre, and a bad soundtrack, featuring the voices of Jonathan Winters,
as The Thief, and Matthew Broderick, as The Cobbler. Both characters were
conceived by Williams as silent stars, without voice. Neither Broderick's
endless plot commentaries nor Winters' unceasing and unfunny monologues
add anything but noise to the film.<BR>
<BR>
</FONT><IMG SRC="../images/williams03.gif" WIDTH="216" HEIGHT="146" ALIGN=
"RIGHT" NATURALSIZEFLAG="3" ALT="The Thief tries to escape through an Escher-like landscape in the palace"
BORDER="1"><FONT COLOR="#000000" SIZE=-2>The Thief tries to escape through
an Escher-like landscape in the palace</FONT></P>
<P><B><FONT COLOR="#000000">Unlike Anything Attempted Before</FONT></B><FONT
COLOR="#000000"><BR>
The story of <I>The Thief and the Cobbler </I>began in London in the late
1960s, as Richard Williams began work on an obscure film which was to evolve
over many years before reaching its final form. Working with illustrator
Errol Le Cain and Art Designer Roy Naisbitt, Williams found a unique style
based on Oriental and Eastern art, Unlike anything attempted before or
since, and completely unlike Disney's<I> Aladdin, The Thief </I>did not
attract full financial backing from a major studio until early 1990. Williams,
having won an Oscar for his short film <I>A Christmas Carol </I>in 1972,
picked up two more Oscars in 1990 for his groundbreaking work on <I>Who
Framed Roger Rabbit.</I> Bankable at last, Williams was courted by producer
Jake Eberts, and Warner Bros. agreed to finance and distribute <I>The Thief.</I><BR>
<BR>
Work began in earnest in the spring of 1990. Williams and his team of London
animators labored to produce a work of lyrical beauty. Those fortunate
enough to have seen the original director's cut (much-duplicated copies
of which circulate throughout the close-knit animation industry) will be
familiar with a work of epic grandeur and remarkable ambition. The destruction
of the evil One-Eye's war machine at the end of the film is a sequence
of breathtaking complexity and beauty, a symphony of destruction in which
sound effects, music and animation combine to create an almost balletic
climax. The film, including this final sequence, was entirely hand drawn,
traced and painted in the traditional fashion onto celluloid, It is often
said that much of the impressive work in <I>The Thief </I>could be easily
done today by computer-generated animation, but this is to miss the point.
The use of Persian motifs lends the film a graphic two-and-a half-dimensional
quality which defies normal physical laws. Such an eccentric vision could
only have been produced by a human hand.<BR>
<BR>
Williams, a perfectionist to the end, was unable to complete <I>The Thief</I>
on time. In late 1991, the Completion Bond Company, worried by the size
of their financial exposure, sent animator Fred Calvert to London to assess
the situation. In early 1992, despite the fact that the film was just 10-15
minutes from completion, Warner Bros. pulled out of the project, and the
bond company lost their nerve. <I>The Thief </I>was completed from Los
Angeles, farmed out around the world by Calvert, and was eventually picked
up by Miramax. As Williams' involvement with the movie came to an end,
the destruction of his life's work had begun.<BR>
<BR>
Fred Calvert's involvement with the completion of the film is perhaps the
most discreditable aspect of the story. Unable to appreciate the remarkable
nature of the project he had inherited, he sent the inevitable song sequences
to be completed in Korea by animators used to working on Saturday morning
children's cartoons. That these sequences look grotesque when juxtaposed
with Williams' original work should have come as no surprise. Fred Calvert's
leading role in butchering <I>The Thief</I> has become perhaps his most
infamous contribution to the medium.<BR>
<BR>
</FONT><IMG SRC="../images/williams04.gif" WIDTH="216" HEIGHT="141" ALIGN=
"LEFT" NATURALSIZEFLAG="3" ALT="The Thief hiding in a plant" BORDER="1"><FONT
COLOR="#000000" SIZE=-2>The Thief hiding in a plant</FONT></P>
<P><B><FONT COLOR="#000000">The Spirit of the Film</FONT></B><FONT COLOR="#000000"><BR>
It is hard, looking at this Miramax video release, to find the spirit of
the film as it was originally conceived. The character of The Thief was
intended as a mute, a Chaplinesque primitive, subtle and understated. By
stealing the three golden balls which protect the Golden City, he unwittingly
creates havoc and destruction around him. Superimposed over these scenes
is Jonathan Winters' voice, ceaselessly cracking pointless jokes like an
unwanted barroom companion. It is as if those responsible for the completion
of the film were terrified of silence, overlaying every quiet moment in
the film with endless chatter. Matthew Broderick's narration strives to
explain what does not need explaining, robbing the story of subtlety or
surprises. The film condescends to the the audience, insulting its intelligence.<BR>
<BR>
There remains some beautiful animation in this fractured version of Richard
Williams' epic; these include the opening sequence, where <I>The Thief
and The Cobbler</I> get tangled up with each other and roll down the steps
of the Cobbler's shop, interrupting Zig Zag's march through the city, the
chase through the palace through Escher-like optical illusions, and a little
of the final war machine sequence. For those courageous enough to sit it
out, I recommend watching with the sound turned off. Save for Vincent Price's
brilliant valedictory performance as Zig Zag, the evil Grand Vizier, all
but a handful of the carefully selected original voice talents have been
replaced with other, less suitable, actors. Even John Leatherbarrow's superb
camerawork has been made to appear unremarkable, the once subtle colors
now vulgar and garish. Finally, the substitution of Baghdad for the Golden
City seems in extraordinarily bad taste for a film originally released
shortly after the Gulf War.<BR>
<BR>
</FONT><IMG SRC="../images/williams05.gif" WIDTH="216" HEIGHT="145" ALIGN=
"RIGHT" NATURALSIZEFLAG="3" ALT="Zig Zag, the Grand Vizer and The Sultan"
BORDER="1"><FONT COLOR="#000000" SIZE=-2>Zig Zag, the Grand Vizer and The
Sultan</FONT><FONT COLOR="#000000"></FONT></P>
<P><FONT COLOR="#000000">Dick Williams spent 30 years trying to pull off
an animation masterpiece, a true work of art, the like of which may never
be seen or attempted again. It is sad that so little of his original vision
made it into this video release. It is probably little consolation to Williams
himself that the Completion Bond Company has since gone out of business,
largely as a result of the costs of completing The Thief. <BR>
<BR>
<B><I>The Thief and the Cobbler,</I> partial credits:<BR>
Director: </B>Richard Williams, <B>Screenplay: </B>Richard Williams, <B>Executive
Producer:</B> Jake Eberts, <B>Musical Score:</B> Robert Folk, <B>Songs
by:</B> Robert Folk & Norman Gimbel, <B>Producers:</B> Richard Williams
& Imogen Sutton, <B>Director, L.A. Production:</B> Fred Calvert, <B>Producer,
L.A.:</B> Bette L. Smith, <B>Art Director:</B> Roy Naisbitt, <B>Master
Animator:</B> Ken Harris, Background Stylist: Errol LeCain, <B>Director
of Photography:</B> John Leatherbarrow.<BR>
<B>Artistic Supervisors:</B> <B>Special Effects: </B>John M. Cousen, <B>Character
Animation:</B> Neil Boyle & Tim Watts, <B>Background:</B> Paul Dilworth.<BR>
<B>Lead Animators</B> included: Art Babbitt, Steven Evangelatos, Emery
Hawkins, Richard Williams, Alex Williams, and many others. <BR>
<BR>
<I>Alex Williams is an animator at Warner Bros. Feature Animation, currently
working on </I>The Quest For Camelot. <I>He spent two years animating on
</I>The Thief and the Cobbler, <I>which was directed by his father Richard.
He also teaches an animation class at The California Institute of The Arts,
and does a weekly cartoon strip </I>Queen's Counsel <I>for</I> The London
Times.</FONT></P>
<P ALIGN=CENTER><A HREF="../toc1.12.html">Back to the Table of Contents</A><BR>
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<P><HR ALIGN=LEFT>© 1997 <A HREF="http://www.awn.com/">Animation World
Network</A>
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>
> [Animation
> World Magazine](http://www.awn.com/mag), Issue 1.12, March 1997
>
>
>
> ---
>
>
>
>
> # The Thief And The Cobbler
>
>
> by Alex Williams
>
>
> ***Editor's Note:*
> In August 1995, a film titled** Arabian
> Knights *briefly appeared in American movie houses, hardly making a dent
> in the box office. Nevertheless, many in the animation community started
> to realize that this was no ordinary film, but rather a film assembled
> from the ruins of Richard Williams' magnum opus,* The Thief and the
> Cobbler, *which has now been released to the home video under its original
> title. While* Animation World Magazine *usually does not like to review
> films in their video version after they have been shown theatrically, we
> thought it would be interesting to have Richard Williams' son Alex take
> a gander at this version, which he had not seen before, and give us his
> reactions; some of my own comments on the film can be found in this issue's* [Editor's Notebook.](edito1.12.html)
>
>
>
> ![The Cobbler and The Princess](../images/williams02.gif)The Cobbler and The Princess
>
>
> *The Thief and the Cobbler*
> was to have been the greatest animated film ever made, the culmination
> of the a lifetime's work by master animator Richard Williams. Based on
> the art of the Middle East, and in particular on the miniatures produced
> in Safavid Persia circa 1500, the film was at least 30 Years in the making,
> and became a legend in the animation industry.
>
>
>
> The version released on video by Miramax, described as "a musically-charged
> animated epic created by Richard Williams, the Oscar winning animator of
> *Who Framed Roger Rabbit,*" is a degraded version of Williams'
> masterpiece, hardly worthy of the name it bears. lt is the same film formerly
> released theatrically as *Arabian Knight,* a work of such startling
> bad taste that it discredits all who were involved in its completion. The
> film is more or less unwatchable, a collage of laughably third rate animation
> interspersed with scenes of remarkable beauty, leftovers from the original
> cut. Worst of all are the three song sequences, banal and depressingly
> mediocre, and a bad soundtrack, featuring the voices of Jonathan Winters,
> as The Thief, and Matthew Broderick, as The Cobbler. Both characters were
> conceived by Williams as silent stars, without voice. Neither Broderick's
> endless plot commentaries nor Winters' unceasing and unfunny monologues
> add anything but noise to the film.
>
>
>
> ![The Thief tries to escape through an Escher-like landscape in the palace](../images/williams03.gif)The Thief tries to escape through
> an Escher-like landscape in the palace
>
>
> **Unlike Anything Attempted Before**
>
> The story of *The Thief and the Cobbler* began in London in the late
> 1960s, as Richard Williams began work on an obscure film which was to evolve
> over many years before reaching its final form. Working with illustrator
> Errol Le Cain and Art Designer Roy Naisbitt, Williams found a unique style
> based on Oriental and Eastern art, Unlike anything attempted before or
> since, and completely unlike Disney's *Aladdin, The Thief* did not
> attract full financial backing from a major studio until early 1990. Williams,
> having won an Oscar for his short film *A Christmas Carol* in 1972,
> picked up two more Oscars in 1990 for his groundbreaking work on *Who
> Framed Roger Rabbit.* Bankable at last, Williams was courted by producer
> Jake Eberts, and Warner Bros. agreed to finance and distribute *The Thief.*
>
>
>
> Work began in earnest in the spring of 1990. Williams and his team of London
> animators labored to produce a work of lyrical beauty. Those fortunate
> enough to have seen the original director's cut (much-duplicated copies
> of which circulate throughout the close-knit animation industry) will be
> familiar with a work of epic grandeur and remarkable ambition. The destruction
> of the evil One-Eye's war machine at the end of the film is a sequence
> of breathtaking complexity and beauty, a symphony of destruction in which
> sound effects, music and animation combine to create an almost balletic
> climax. The film, including this final sequence, was entirely hand drawn,
> traced and painted in the traditional fashion onto celluloid, It is often
> said that much of the impressive work in *The Thief* could be easily
> done today by computer-generated animation, but this is to miss the point.
> The use of Persian motifs lends the film a graphic two-and-a half-dimensional
> quality which defies normal physical laws. Such an eccentric vision could
> only have been produced by a human hand.
>
>
>
> Williams, a perfectionist to the end, was unable to complete *The Thief*
> on time. In late 1991, the Completion Bond Company, worried by the size
> of their financial exposure, sent animator Fred Calvert to London to assess
> the situation. In early 1992, despite the fact that the film was just 10-15
> minutes from completion, Warner Bros. pulled out of the project, and the
> bond company lost their nerve. *The Thief* was completed from Los
> Angeles, farmed out around the world by Calvert, and was eventually picked
> up by Miramax. As Williams' involvement with the movie came to an end,
> the destruction of his life's work had begun.
>
>
>
> Fred Calvert's involvement with the completion of the film is perhaps the
> most discreditable aspect of the story. Unable to appreciate the remarkable
> nature of the project he had inherited, he sent the inevitable song sequences
> to be completed in Korea by animators used to working on Saturday morning
> children's cartoons. That these sequences look grotesque when juxtaposed
> with Williams' original work should have come as no surprise. Fred Calvert's
> leading role in butchering *The Thief* has become perhaps his most
> infamous contribution to the medium.
>
>
>
> ![The Thief hiding in a plant](../images/williams04.gif)The Thief hiding in a plant
>
>
> **The Spirit of the Film**
>
> It is hard, looking at this Miramax video release, to find the spirit of
> the film as it was originally conceived. The character of The Thief was
> intended as a mute, a Chaplinesque primitive, subtle and understated. By
> stealing the three golden balls which protect the Golden City, he unwittingly
> creates havoc and destruction around him. Superimposed over these scenes
> is Jonathan Winters' voice, ceaselessly cracking pointless jokes like an
> unwanted barroom companion. It is as if those responsible for the completion
> of the film were terrified of silence, overlaying every quiet moment in
> the film with endless chatter. Matthew Broderick's narration strives to
> explain what does not need explaining, robbing the story of subtlety or
> surprises. The film condescends to the the audience, insulting its intelligence.
>
>
>
> There remains some beautiful animation in this fractured version of Richard
> Williams' epic; these include the opening sequence, where *The Thief
> and The Cobbler* get tangled up with each other and roll down the steps
> of the Cobbler's shop, interrupting Zig Zag's march through the city, the
> chase through the palace through Escher-like optical illusions, and a little
> of the final war machine sequence. For those courageous enough to sit it
> out, I recommend watching with the sound turned off. Save for Vincent Price's
> brilliant valedictory performance as Zig Zag, the evil Grand Vizier, all
> but a handful of the carefully selected original voice talents have been
> replaced with other, less suitable, actors. Even John Leatherbarrow's superb
> camerawork has been made to appear unremarkable, the once subtle colors
> now vulgar and garish. Finally, the substitution of Baghdad for the Golden
> City seems in extraordinarily bad taste for a film originally released
> shortly after the Gulf War.
>
>
>
> ![Zig Zag, the Grand Vizer and The Sultan](../images/williams05.gif)Zig Zag, the Grand Vizer and The
> Sultan
>
>
> Dick Williams spent 30 years trying to pull off
> an animation masterpiece, a true work of art, the like of which may never
> be seen or attempted again. It is sad that so little of his original vision
> made it into this video release. It is probably little consolation to Williams
> himself that the Completion Bond Company has since gone out of business,
> largely as a result of the costs of completing The Thief.
>
>
>
> ***The Thief and the Cobbler,* partial credits:
>
> Director:** Richard Williams, **Screenplay:** Richard Williams, **Executive
> Producer:** Jake Eberts, **Musical Score:** Robert Folk, **Songs
> by:** Robert Folk & Norman Gimbel, **Producers:** Richard Williams
> & Imogen Sutton, **Director, L.A. Production:** Fred Calvert, **Producer,
> L.A.:** Bette L. Smith, **Art Director:** Roy Naisbitt, **Master
> Animator:** Ken Harris, Background Stylist: Errol LeCain, **Director
> of Photography:** John Leatherbarrow.
>
> **Artistic Supervisors:** **Special Effects:** John M. Cousen, **Character
> Animation:** Neil Boyle & Tim Watts, **Background:** Paul Dilworth.
>
> **Lead Animators** included: Art Babbitt, Steven Evangelatos, Emery
> Hawkins, Richard Williams, Alex Williams, and many others.
>
>
>
> *Alex Williams is an animator at Warner Bros. Feature Animation, currently
> working on* The Quest For Camelot. *He spent two years animating on* The Thief and the Cobbler, *which was directed by his father Richard.
> He also teaches an animation class at The California Institute of The Arts,
> and does a weekly cartoon strip* Queen's Counsel *for* The London
> Times.
>
>
> [Back to the Table of Contents](../toc1.12.html)
>
> [Feedback?](../../feedbackforum.html)[Past Issues](../../../infovault/magarchives.html)
>
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<CENTER><h3>The World of Mime Theatre is devoted <br>to the promotion of Mime as a
specialized theatrical art.<br>
Its goals are education, information exchange, entertainment, and providing the <br>opportunity to connect people involved and interested in Mime Theatre around the world.</h3></CENTER>
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<td width=16% align=center valign="top"><a href="library.html"><b>LIBRARY</b></a><br><a href="library.html"><IMG SRC="images/library2.gif" width=62 height=53 border="0" alt="Library"></a><p><FONT SIZE=2>Articles and Reference<br>About the Art of<br>Mime Theatre</FONT></td>
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<td width=17% align=center valign="top"><a href="performance.html"><b>PERFORMANCE</b></a><br><a href="performance.html"><IMG SRC="images/performance2.gif" width=63 height=55 border="0" alt="Performance"></a><p><FONT SIZE=2>The Who and Where of<br>Mime Performance<br>Around the World:<br>
<b>· </b>
Mime Artists <b>·</b><br>
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Companies & Troupes <b>·</b><br>
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Festivals <b>·</b></FONT></td>
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<td align=center bgcolor="#888888" colspan=3><b>Countries Currently Represented at The World of Mime Theatre</b></td>
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<td align=center><IMG SRC="images/flags/ar.gif" width=15 height=10 border=0 alt="Argentina"></td>
<td align=center><IMG SRC="images/flags/am.gif" width=15 height=10 border=0 alt="Armenia"></td>
<td align=center><IMG SRC="images/flags/ausm.gif" width=15 height=10 border=0 alt="Australia"></td>
<td align=center><IMG SRC="images/flags/azsm.gif" width=15 height=10 border=0 alt="Azerbaijan"></td>
<td align=center><IMG SRC="images/flags/besm.gif" width=15 height=10 border=0 alt="Belgium"></td>
<td align=center><IMG SRC="images/flags/bl.gif" width=15 height=10 border=0 alt="Bulgaria"></td>
<td align=center><img src="images/flags/brsm.gif" alt="Brazil" width="15" height="10"></td>
<td align=center><IMG SRC="images/flags/casm.gif" width=15 height=10 border=0 alt="Canada"></td>
<td align=center><IMG SRC="images/flags/cosm.gif" border=0 alt="Columbia" width="15" height="10"></td>
<td align=center><IMG SRC="images/flags/cz.gif" width=15 height=10 border=0 alt="Czech Republic"></td>
<td align=center><IMG SRC="images/flags/england.gif" width=15 height=10 border=0 alt="England - UK"></td>
<td align=center><IMG SRC="images/flags/fi.gif" width=15 height=10 border=0 alt="Finland"></td>
<td align=center><IMG SRC="images/flags/fr.gif" width=15 height=10 border=0 alt="France"></td>
<td align=center bgcolor="#888888"> </td>
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</table></td>
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<td align=center bgcolor="#888888"><table width="100%" height="306" border="0" cellpadding="0" cellspacing="0">
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<td><div align="center"><IMG SRC="images/flags/yu.gif" width=15 height=10 border=0 alt="Yugoslavia"></div></td>
</tr>
<tr>
<td><div align="center"><img border="0" src="images/flags/vesm.gif" alt="Venezuela" width="15" height="10"></div></td>
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<td><div align="center"><img border="0" src="images/flags/uysm.gif" alt="Uruguay" width="15" height="10"></div></td>
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<td><div align="center"><IMG SRC="images/flags/usasm.gif" border=0 alt="United States (USA)" width="15" height="10"></div></td>
</tr>
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<td><div align="center"><IMG SRC="images/flags/ukrainesm.gif" border=0 alt="Ukraine" width="15" height="10"></div></td>
</tr>
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<td><div align="center"><IMG SRC="images/flags/swsm.gif" border=0 alt="Switzerland" width="10" height="10"></div></td>
</tr>
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<td><div align="center"><IMG SRC="images/flags/es.gif" width=15 height=10 border=0 alt="Spain"></div></td>
</tr>
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<td><IMG SRC="images/flags/lbsm.gif" border=0 alt="Lebanon" width="15" height="10"></td>
</tr>
</table></td>
<td bgcolor="#FFFFFF"><div align="center"><img border="0" src="images/Wmtmap.gif" width="502" height="306"></div></td>
<td align=center bgcolor="#888888"><table width="100%" height="306" border="0" cellpadding="0" cellspacing="0">
<tr>
<td><div align="center"><img src="images/flags/gesm.gif" border="0" alt="Georgia" width="17" height="10"></div></td>
</tr>
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<td><div align="center"><IMG SRC="images/flags/de.gif" width=15 height=10 border=0 alt="Germany"></div></td>
</tr>
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<td><div align="center"><IMG SRC="images/flags/grsm.gif" border=0 alt="Greece" width="15" height="10"></div></td>
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<td><div align="center"><IMG SRC="images/flags/id.gif" width=15 height=10 border=0 alt="India"></div></td>
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<td><div align="center"><IMG SRC="images/flags/ilsm.gif" border=0 alt="Israel" width="15" height="10"></div></td>
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<td><div align="center"><IMG SRC="images/flags/it.gif" border=0 alt="Italy" width="15" height="10"></div></td>
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<td><div align="center"><IMG SRC="images/flags/jpsm.gif" border=0 alt="Japan" width="15" height="10"></div></td>
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<td><IMG SRC="images/flags/mksm.gif" border=0 alt="Macedonia" width="15" height="10"></td>
</tr>
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<td colspan=3><table width=100% border=0 cellspacing=0>
<tr>
<td align=center bgcolor="#888888"> </td>
<td align=center><IMG SRC="images/flags/krsm.gif" border=0 alt="South Korea" width="15" height="10"></td>
<td align=center><IMG SRC="images/flags/sv.gif" width=15 height=10 border=0 alt="Slovakia"></td>
<td align=center><IMG SRC="images/flags/slsm.gif" border=0 alt="Scotland - UK" width="15" height="10"></td>
<td align=center><IMG SRC="images/flags/russia.gif" width=15 height=10 border=0 alt="Russia"></td>
<td align=center><IMG SRC="images/flags/ro.gif" width=15 height=10 border=0 alt="Romania"></td>
<td align=center><IMG SRC="images/flags/p-rsm.gif" width=15 height=10 border=0 alt="Puerto Rico"></td>
<td align=center><IMG SRC="images/flags/pl.gif" width=15 height=10 border=0 alt="Poland"></td>
<td align=center><IMG SRC="images/flags/pesm.gif" border=0 alt="Perú" width="15" height="10"></td>
<td align=center><IMG SRC="images/flags/nzsm.gif" border=0 alt="New Zealand" width="15" height="10"></td>
<td align=center><IMG SRC="images/flags/nl.gif" width=15 height=10 border=0 alt="Netherlands"></td>
<td align=center><IMG SRC="images/flags/md.gif" width=15 height=10 border=0 alt="Moldova"></td>
<td align=center><IMG SRC="images/flags/mx.gif" width=15 height=10 border=0 alt="Mexico"></td>
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</td>
<td width="33%">
<p align="center"><b>Named "The World's Best Website on Mime"
by <a href="http://www.beesker.com/" target="_blank">Beesker</a></b></td>
<td width="33%"><div align="center"><strong>Named "Best of the Web" by<br>
<a href="http://www.nypl.org/" target="_blank">The New York Public Library</a></strong> </div></td>
</tr>
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<p align="center">
The World of Mime Theatre was created and is maintained by <a href="artists.html#Salm">Lorin Eric Salm</a>.
<p align="center">
The design of this website, and all text and graphics contained herein,<br>
are ©1996-2019 The World of Mime Theatre,<br>
except material whose copyrights belong to other parties and
is used here by permission. All rights reserved.<br>
<i><a href="disclaimer.html">"Good faith" disclaimer</a></i><br>
This page last updated 24 February 2014.
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![The World of Mime Theatre](images/logoanimation.gif)
### The World of Mime Theatre is devoted to the promotion of Mime as a
specialized theatrical art.
Its goals are education, information exchange, entertainment, and providing the opportunity to connect people involved and interested in Mime Theatre around the world.
![](images/purpbar1.gif)
| | | | | | |
| --- | --- | --- | --- | --- | --- |
| [**LIBRARY**](library.html)[Library](library.html)Articles and ReferenceAbout the Art ofMime Theatre | [**INFORMATION**](InfoRes.html)[Information & Resources](InfoRes.html)[**& RESOURCES**](InfoRes.html)**·** Schools
& Workshops **·**
**·** Bookstore **·**
**·** Publications **·**
**·** Film & Video **·**
**·** Organizations **·**
**·** Websites **·**
| [**PERFORMANCE**](performance.html)[Performance](performance.html)The Who and Where ofMime PerformanceAround the World:
**·**
Mime Artists **·**
**·**
Companies & Troupes **·**
**·**
Festivals **·** | [**CALENDAR**](calendar.html)[Calendar](calendar.html)Upcoming Shows,Festivals,and Events | [**THEATRE**](links.html)[Theatre Links](links.html)[**LINKS**](links.html)OtherTheatre-Related SitesWorth Visiting | [**SEARCH**](search.html)[Search](search.html)Find ExactlyWhat You'reLooking For |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
|
| |
| --- |
| **Countries Currently Represented at The World of Mime Theatre** |
|
| | | | | | | | | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| | Argentina | Armenia | Australia | Azerbaijan | Belgium | Bulgaria | Brazil | Canada | Columbia | Czech Republic | England - UK | Finland | France | |
|
|
| |
| --- |
| Yugoslavia |
| Venezuela |
| Uruguay |
| United States (USA) |
| Ukraine |
| Switzerland |
| Spain |
| Lebanon |
| |
| |
| --- |
| Georgia |
| Germany |
| Greece |
| India |
| Israel |
| Italy |
| Japan |
| Macedonia |
|
|
| | | | | | | | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| | South Korea | Slovakia | Scotland - UK | Russia | Romania | Puerto Rico | Poland | Perú | New Zealand | Netherlands | Moldova | Mexico | |
|
|
---
| | | |
| --- | --- | --- |
| **[SEND
US FEEDBACK](forms/feedback_form.html)** | **[SIGN OUR GUESTBOOK](gstbk_entry.html)** | **[SUBMIT A NEW LISTING](forms/submit_forms.html)** |
| | | |
| --- | --- | --- |
|
| **Named "The World's Best Website on Mime"
by [Beesker](http://www.beesker.com/)** | **Named "Best of the Web" by
[The New York Public Library](http://www.nypl.org/)** |
The World of Mime Theatre was created and is maintained by [Lorin Eric Salm](artists.html#Salm).
The design of this website, and all text and graphics contained herein,
are ©1996-2019 The World of Mime Theatre,
except material whose copyrights belong to other parties and
is used here by permission. All rights reserved.
*["Good faith" disclaimer](disclaimer.html)*
This page last updated 24 February 2014.
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<div style="position: absolute; top: 111px; left: 52px; width: 189px; height: 154px; z-index: 2;" id="element3"><div align="center"><font face="Helvetica, Arial, sans-serif" class="size18 Helvetica18" color="#000000"><b><i>A Gift</i></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size18 Helvetica18" color="#000000"><b><i>to the</i></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size18 Helvetica18" color="#000000"><b><i>Hearts</i></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size18 Helvetica18" color="#000000"><b><i>of all</i></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size18 Helvetica18" color="#000000"><b><i>People</i></b><br></font></div></div>
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<div style="position: absolute; top: 322px; left: 258px; width: 334px; height: 81px; z-index: 4;" id="element5"><div align="center"><font face="Helvetica, Arial, sans-serif" class="size12 Helvetica12" color="#000000"><b>Miracle, The Sacred White Buffalo</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Born August 20, 1994</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Died September 19, 2004</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>The Heider Farm ~ Janesville, Wisconsin</b><br></font></div></div>
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<div style="position: absolute; top: 17px; left: 8px; width: 573px; height: 50px; z-index: 5;" id="element6"><div align="center"><font face="Helvetica, Arial, sans-serif" class="size24 Helvetica24" color="#000000"><b><i>Welcome To Miracle's Website....</i></b><br></font></div></div>
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<div style="position: absolute; top: 417px; left: 5px; width: 637px; height: 10px; z-index: 6;" id="element7"><img alt="" src="http://www.homestead.com/~media/elements/DecorativeDivider/zig_zag.gif" height="10" width="637" border="0"></div>
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<div style="position: absolute; top: 442px; left: 11px; width: 628px; height: 478px; z-index: 7;" id="element8"><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Miracle, the Sacred White Female Buffalo Calf, was born on the farm of Dave, Valerie, and Corey Heider near Janesville, Wisconsin during the morning of August 20, 1994.  Not an albino, she was considered to be the first white buffalo calf born since 1933.  Furthermore, she was extremely important to the religious beliefs of many American Indian and Canadian First Nations tribes.</b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b></b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>The Lakota, Dakota, and Nakota Nations (known collectively as the Sioux) were considered Miracle's primary spiritual guardians and she played a pivotal role in the fulfillment of their most revered prophecies.  However, her place in the prophecies and beliefs of many tribes made her a highly sacred symbol to many of the American Indian Nations across the continent.  She was seen by a vast number of people as a symbol of hope and renewal for humanity and for harmony between all peoples, all races, in our world today.</b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b></b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Although not American Indian, the Heider family came to view Miracle as a special gift which belonged to the hearts of all people.  Commercialization was not allowed.  They opened their farm to visitors free of charge seven days a week so that people could visit Miracle at the pasture fence.  For safety reasons, visitors were not allowed into the pasture.  Miracle was, after all, a wild buffalo as are the rest of the buffalo on the farm.  Many people came to offer prayers in her presence, some came simply out of curiosity.  Whatever their reason for visiting Miracle and this simple farm, thousands came and few people left unaffected by their time there. </b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b></b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Visitors are still welcome to come pray and/or pay their respects at Miracle's grave on the Heider Farm.  See the Visitor Information link below for details on visiting.</b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b></b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>It is the Heiders' hope that this website will help to bring understanding and answer many of the questions people have had about Miracle.  For those unable to visit Miracle, much of her life can be seen here.</b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b></b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Mitakuye Oyasin.... We Are All Related in the Sacred Hoop of Life.</b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>May It Ever Be So.</b><br></font></div></div>
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<div style="position: absolute; top: 1412px; left: 52px; width: 302px; height: 25px; z-index: 16;" id="element17"><a target="_self" href="Miracle_CampingInfo.html"><img alt="" src="publishImages/index~~element17.gif" height="25" width="302" border="0"></a></div>
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<div style="position: absolute; top: 1450px; left: 17px; width: 520px; height: 99px; z-index: 17;" id="element18"><div align="left"><font face="Helvetica, Arial, sans-serif" class="size14 Helvetica14" color="#000000"><b>Sacred Buffalo Stories, Lore, and Commentary....</b><br></font></div><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b><i>Note:  Out of Respect for The People, no links are provided here which will discuss sacred American Indian spirituality issues except generalized information which can be found in numerous places on the web and in popular books or which has been placed on the web by The People, themselves.</i></b><br></font></div></div>
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<div style="position: absolute; top: 1026px; left: 50px; width: 302px; height: 25px; z-index: 21;" id="element22"><a target="_self" href="Miracle_Walks_On_Articles.html"><img alt="" src="publishImages/index~~element22.gif" height="25" width="302" border="0"></a></div>
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<div style="position: absolute; top: 1737px; left: 15px; width: 230px; height: 35px; z-index: 22;" id="element23"><div align="left"><font face="Helvetica, Arial, sans-serif" class="size14 Helvetica14" color="#000000"><b>Miracle's Life in Words....</b><br></font></div></div>
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<div style="position: absolute; top: 1779px; left: 49px; width: 302px; height: 25px; z-index: 23;" id="element24"><a target="_self" href="Press_MiracleBuffaloBirth.html"><img alt="" src="publishImages/index~~element24.gif" height="25" width="302" border="0"></a></div>
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<div style="position: absolute; top: 1851px; left: 49px; width: 301px; height: 25px; z-index: 24;" id="element25"><a target="_self" href="Miracle_Walks_On_Articles.html"><img alt="" src="publishImages/index~~element25.gif" height="25" width="301" border="0"></a></div>
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<div style="position: absolute; top: 1815px; left: 50px; width: 301px; height: 25px; z-index: 25;" id="element26"><a target="_self" href="MiracleSireMarvin.html"><img alt="" src="publishImages/index~~element26.gif" height="25" width="301" border="0"></a></div>
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<div style="position: absolute; top: 1925px; left: 15px; width: 457px; height: 35px; z-index: 26;" id="element27"><div align="left"><font face="Helvetica, Arial, sans-serif" class="size14 Helvetica14" color="#000000"><b>Link to the Heider's DaVALS Farm Products Website</b><br></font></div></div>
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<div style="position: absolute; top: 1965px; left: 51px; width: 303px; height: 25px; z-index: 29;" id="element30"><a target="_self" href="http://www.homestead.com/davalswhitebuffalofarm/Index.html"><img alt="" src="publishImages/index~~element30.gif" height="25" width="303" border="0"></a></div>
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<div style="position: absolute; top: 2055px; left: 38px; width: 572px; height: 126px; z-index: 37;" id="element38"><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>NOTE:  In accordance with Title 17, U.S.C. Section 107, all material here is posted without profit or payment for non-profit research, educational, and archival purposes only</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b><i></i></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b><i>All Photographs are Copyright, DaVALS White Buffalo Farms, Inc</i></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b><i>(Dates and ID on File)</i></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b><i>All Written Commentary is Copyright, Stephanie M. Schwartz, Freelance Writer</i></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b><i>All Graphics are Copyright 2001, Stellar Designs of Plymouth, Michigan</i></b><br></font></div></div>
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<div style="position: absolute; top: 2989px; left: 422px; width: 206px; height: 129px; z-index: 39;" id="element40"><map name="MAP_10943592"><area alt="Sign In" href="/~site/Scripts_NewGuest/NewGuest.dll?CMD=CMDGetSubmitForm&STYLE=classic/&FORWARDFLAG=true&GBID=10943592&DISPLAY=31&TARGETURL=DEFAULT&EMAILADDRESS=ENC__8fcab10a2e6cd5021e2e533ae8fd079b6f6d&EM=true&CUSTOMVALUE=false&H_H=9550001" target="_parent" title="Submit" shape="rect" coords="14,92,93,119"><area alt="View Entries" href="/~site/Scripts_NewGuest/NewGuest.dll?CMD=CMDGetViewEntriesPage&STYLE=classic/&ENTRYID=&FORWARDFLAG=true&GBID=10943592&DISPLAY=31&TARGETURL=DEFAULT&EMAILADDRESS=ENC__8fcab10a2e6cd5021e2e533ae8fd079b6f6d&EM=true&CUSTOMVALUE=false&H_H=9550001" target="_parent" title="View Entries" shape="rect" coords="113,92,192,119"><area nohref alt="" shape="default"></map><img alt="" src="/~site/tool/Homestead/HC_Objects/Images/HCUser_Guestbook/classic/guestbook.gif" height="129" border="0" width="206" usemap="#MAP_10943592"></div>
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<div style="position: absolute; top: 2469px; left: 399px; width: 240px; height: 190px; z-index: 40;" id="element41"><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Guest Book</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>READ ONLY BELOW:</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Miracle's First Guest Books Below Have Been Printed Out and Sent To The Heider Family.</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>They cover</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>February 1, 2001 to January 06, 2008,</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>257,281 Website Visitors,</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>and</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>1,145 Guestbook Messages</b><br></font></div></div>
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<div style="position: absolute; top: 3314px; left: 219px; width: 179px; height: 62px; z-index: 49;" id="element50"><div align="left"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Do Not Sign This Book ----></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>See Above for Current</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Guestbook!</b><br></font></div></div>
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<div style="position: absolute; top: 3px; left: 7px; width: 641px; height: 401px; z-index: 52;" id="element53"><table cellpadding="0" cellspacing="0" border="0"><tr><td bgcolor="#7F7F7F" colspan="6"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=127&g=127&b=127" height="2" width="639" border="0"></td><td><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetCornerGif&w=2&h=2&r2=127&g2=127&b2=127&r=0&g=0&b=0" height="2" width="2" border="0"></td></tr><tr><td bgcolor="#7F7F7F" rowspan="5"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=127&g=127&b=127" height="397" width="2" border="0"></td><td bgcolor="#000000" colspan="5"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=0&g=0&b=0" height="2" width="637" border="0"></td><td bgcolor="#000000" rowspan="6"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=0&g=0&b=0" height="399" width="2" border="0"></td></tr><tr><td bgcolor="#000000" rowspan="4"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=0&g=0&b=0" height="395" width="2" border="0"></td><td bgcolor="#000000" colspan="2"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=0&g=0&b=0" height="2" width="631" border="0"></td><td><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetCornerGif&w=2&h=2&r=127&g=127&b=127&r2=0&g2=0&b2=0" height="2" width="2" border="0"></td><td bgcolor="#000000" rowspan="4"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=0&g=0&b=0" height="395" width="2" border="0"></td></tr><tr><td bgcolor="#000000"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=0&g=0&b=0" height="389" width="2" border="0"></td><td><img alt="" src="/tp.gif" height="389" width="629" border="0"></td><td bgcolor="#7F7F7F" rowspan="2"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=127&g=127&b=127" height="391" width="2" border="0"></td></tr><tr><td><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetCornerGif&w=2&h=2&r=127&g=127&b=127&r2=0&g2=0&b2=0" height="2" width="2" border="0"></td><td bgcolor="#7F7F7F"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=127&g=127&b=127" height="2" width="629" border="0"></td></tr><tr><td bgcolor="#000000" colspan="3"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=0&g=0&b=0" height="2" width="633" border="0"></td></tr><tr><td><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetCornerGif&w=2&h=2&r2=127&g2=127&b2=127&r=0&g=0&b=0" height="2" width="2" border="0"></td><td bgcolor="#000000" colspan="5"><img alt="" src="http://www.homestead.com/~site/Scripts_Shapes/shapes.dll?CMD=GetRectangleGif&r=0&g=0&b=0" height="2" width="637" border="0"></td></tr></table></div>
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<div style="position: absolute; top: 2863px; left: 200px; width: 192px; height: 62px; z-index: 53;" id="element54"><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>Do Not Sign This Book  ----></b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#000000"><b>See Above for Current Guestbook!</b><br></font></div></div>
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<div style="position: absolute; top: 1051px; left: 399px; width: 232px; height: 146px; z-index: 57;" id="element58"><div align="center"><font face="Helvetica, Arial, sans-serif" class="size12 Helvetica12" color="#FFFFFF"><b>Another</b></font><font face="Helvetica, Arial, sans-serif" class="size12 Helvetica12" color="#FFFFFF"><b> Sacred White Buffalo Calf Born on the</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size12 Helvetica12" color="#FFFFFF"><b>Heider Farm</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size10 Helvetica10" color="#FFFFFF"><b>August 25, 2006 - November 26, 2006</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size12 Helvetica12" color="#FFFFFF"><b>Click Here to read about his brief life,</b><br></font></div><div align="center"><font face="Helvetica, Arial, sans-serif" class="size14 Helvetica14" color="#FFFFFF"><b><i><a target="_blank" href="http://www.whitebuffalomiracle2.homestead.com">Miracle's Second Chance</a></i></b><br></font></div></div>
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Miracle, the Sacred White Buffalo - Janesville, Wisconsin
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***A Gift***
***to the***
***Hearts***
***of all***
***People***
![](files/wbufbaby.jpg)
**Miracle, The Sacred White Buffalo**
**Born August 20, 1994**
**Died September 19, 2004**
**The Heider Farm ~ Janesville, Wisconsin**
***Welcome To Miracle's Website....***
![](http://www.homestead.com/~media/elements/DecorativeDivider/zig_zag.gif)
**Miracle, the Sacred White Female Buffalo Calf, was born on the farm of Dave, Valerie, and Corey Heider near Janesville, Wisconsin during the morning of August 20, 1994. Not an albino, she was considered to be the first white buffalo calf born since 1933. Furthermore, she was extremely important to the religious beliefs of many American Indian and Canadian First Nations tribes.**
**The Lakota, Dakota, and Nakota Nations (known collectively as the Sioux) were considered Miracle's primary spiritual guardians and she played a pivotal role in the fulfillment of their most revered prophecies. However, her place in the prophecies and beliefs of many tribes made her a highly sacred symbol to many of the American Indian Nations across the continent. She was seen by a vast number of people as a symbol of hope and renewal for humanity and for harmony between all peoples, all races, in our world today.**
**Although not American Indian, the Heider family came to view Miracle as a special gift which belonged to the hearts of all people. Commercialization was not allowed. They opened their farm to visitors free of charge seven days a week so that people could visit Miracle at the pasture fence. For safety reasons, visitors were not allowed into the pasture. Miracle was, after all, a wild buffalo as are the rest of the buffalo on the farm. Many people came to offer prayers in her presence, some came simply out of curiosity. Whatever their reason for visiting Miracle and this simple farm, thousands came and few people left unaffected by their time there.**
**Visitors are still welcome to come pray and/or pay their respects at Miracle's grave on the Heider Farm. See the Visitor Information link below for details on visiting.**
**It is the Heiders' hope that this website will help to bring understanding and answer many of the questions people have had about Miracle. For those unable to visit Miracle, much of her life can be seen here.**
**Mitakuye Oyasin.... We Are All Related in the Sacred Hoop of Life.**
**May It Ever Be So.**
![](http://www.homestead.com/~media/elements/DecorativeDivider/zig_zag.gif)
**Miracle's Life and Color Changes in Pictures....**
[![](publishImages/index~~element11.gif)](MiracleEarlyDays.html)
[![](publishImages/index~~element12.gif)](MiracleEarlyYears.html)
[![](publishImages/index~~element13.gif)](Miracle_and_Calves.html)
**Visiting Miracle at the Heider Farm....**
[![](publishImages/index~~element15.gif)](Miracle_ChiefArvol.html)
[![](publishImages/index~~element16.gif)](Miracle_VisitorInfo.html)
[![](publishImages/index~~element17.gif)](Miracle_CampingInfo.html)
**Sacred Buffalo Stories, Lore, and Commentary....**
***Note: Out of Respect for The People, no links are provided here which will discuss sacred American Indian spirituality issues except generalized information which can be found in numerous places on the web and in popular books or which has been placed on the web by The People, themselves.***
[![](publishImages/index~~element19.gif)](SiouxSacredWhiteBuffalo.html)
[![](publishImages/index~~element20.gif)](SacredWhiteBuffaloStories.html)
[![](publishImages/index~~element21.gif)](SacredBuffaloHistoryCommentary.html)
[![](publishImages/index~~element22.gif)](Miracle_Walks_On_Articles.html)
**Miracle's Life in Words....**
[![](publishImages/index~~element24.gif)](Press_MiracleBuffaloBirth.html)
[![](publishImages/index~~element25.gif)](Miracle_Walks_On_Articles.html)
[![](publishImages/index~~element26.gif)](MiracleSireMarvin.html)
**Link to the Heider's DaVALS Farm Products Website**
[![](publishImages/index~~element28.gif)](Miracle_GenCommentary.html)
[![](publishImages/index~~element29.gif)](Miracle_NA_Commentary.html)
[![](publishImages/index~~element30.gif)](http://www.homestead.com/davalswhitebuffalofarm/Index.html)
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This page was last updated on: March 31, 2009
***Website Design, Creation, and Maintenance Donated by***
**Webmaster: Stephanie M. Schwartz**
**Denver, Colorado**
**[SilvrDrach@gmail.com](mailto:SilvrDrach@gmail.com)**
***Graphic Artwork Created and Donated by***
**[Stellar Designs](mailto:Befogged@aol.com)** **of**
**Plymouth, Michigan**
![](/~site/tool/Homestead/HC_Objects/Images/HCUser_Guestbook/classic/guestbook.gif)
[![](publishImages/index~~element36.gif)](Miracle1998thru2000.html)
[![](publishImages/index~~element37.gif)](Miracle2001thru2003.html)
**NOTE: In accordance with Title 17, U.S.C. Section 107, all material here is posted without profit or payment for non-profit research, educational, and archival purposes only**
***All Photographs are Copyright, DaVALS White Buffalo Farms, Inc***
***(Dates and ID on File)***
***All Written Commentary is Copyright, Stephanie M. Schwartz, Freelance Writer***
***All Graphics are Copyright 2001, Stellar Designs of Plymouth, Michigan***
[![](publishImages/index~~element39.gif)](Miracle_Heider_Lectures.html)
![](/~site/tool/Homestead/HC_Objects/Images/HCUser_Guestbook/classic/guestbook.gif)
**Guest Book**
**READ ONLY BELOW:**
**Miracle's First Guest Books Below Have Been Printed Out and Sent To The Heider Family.**
**They cover**
**February 1, 2001 to January 06, 2008,**
**257,281 Website Visitors,**
**and**
**1,145 Guestbook Messages**
![](http://www.homestead.com/~media/elements/DecorativeDivider/line_rainbow.gif)
![](/~site/tool/Homestead/HC_Objects/Images/HCUser_Guestbook/classic/guestbook.gif)
**<--** **Sign Here**
[![](publishImages/index~~element45.gif)](Miracle_Whitehorse_Sculptures.html)
**Do Not Sign This Book ---->**
**See Above for Current Guestbook!**
![](publishImages/index~~element47.gif)
**Do Not Sign This Book ---->**
**See Above for Current**
**![](/tp.gif)![](/tp.gif)Guestbook!**
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**Do Not Sign This Book ---->**
**See Above for Current**
**Guestbook!**
![](/~site/tool/Homestead/HC_Objects/Images/HCUser_Guestbook/classic/guestbook.gif)
[![](publishImages/index~~element52.gif)](Miracle_Pictures_Aug_2004.html)
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**Do Not Sign This Book ---->**
**See Above for Current Guestbook!**
![](/~site/tool/Homestead/HC_Objects/Images/HCUser_Guestbook/classic/guestbook.gif)
[![](publishImages/index~~element56.gif)](Miracle_Updates.html)
[![](publishImages/index~~element57.gif)](Miracle_GerryPierce_CrossesOver.html)
**Another** **Sacred White Buffalo Calf Born on the**
**Heider Farm**
**August 25, 2006 - November 26, 2006**
**Click Here to read about his brief life,**
***[Miracle's Second Chance](http://www.whitebuffalomiracle2.homestead.com)***
**Do Not Sign This Book ---->**
**See Above for Current Guestbook!**
![](/~site/tool/Homestead/HC_Objects/Images/HCUser_Guestbook/classic/guestbook.gif)
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<td valign="top" width="75%">Welcome to the web site of the <b>Massachusetts Cultivated Blueberry Growers Association</b>.<p>We meet bi-annually and aim to educate both the public and the blueberry growers on subjects like pruning techniques, fertilizer, yield maximization.</p>
<p>Membership is open to anyone that is interested in growing blueberries, even if you only have one bush. Annual dues are $20</p>
<p><font size="2">On this web site, you can find a <a href="member_list.html">list</a> and a <a href="member_map.html">map</a> with locations of blueberry farms in Massachusetts.</font></p>
<p align="center">
<img border="0" src="images/MCBGA%20110517.JPG" width="480" height="329" alt="Fall 2017 meeting" style="border-style: outset; border-width: 2px"><br>
<font size="1">growers panel with moderator Elizabeth Garofalo (Mass Coop Extension) during the farmer-2-farmer session at the 2017 annual meeting</font></p>
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<p>Next seminar:</p>
<p><font size="2">N<b>ovember 5<sup>th</sup> 2023</b><br>
Wrentham Senior Center<br>
400 Taunton Street<br>
Wrentham, MA</font></p>
<p><b><font size="1">speaker:</font></b><font size="2"><b><br>
</b>Mary Conclin<br>
<i>How to successfully grow blueberries<br>
while dealing with climate change</i></font></p>
<p><font size="1"><b>agenda:</b></font><font size="2"><br>
<b>12:30</b> Light Italian buffet lunch ($20/ea)</font><font SIZE="3"><br>
</font><font size="2"><b>1:30</b> Annual business meeting<br>
<b>2:00</b> Presentation<br>
<b>3:15</b> Hands-on pruning demo at <br>
Gianetti's Blueberry Farm<br>
557 Union Street<br>
Franklin, MA<br>
(9 minutes from the Franklin<br>
Senior Center)</font></p><font SIZE="2">
<p><font size="1">Please <b>RSVP</b> before November<br>
<a href="mailto:eap1226@aol.com?subject=RSVP MCBGA 2016 summer meeting">Elisabeth Patt</a></font></p>
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Massachusetts Cultivated Blueberry Growers Association
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| --- | --- |
| Welcome to the web site of the **Massachusetts Cultivated Blueberry Growers Association**.We meet bi-annually and aim to educate both the public and the blueberry growers on subjects like pruning techniques, fertilizer, yield maximization.
Membership is open to anyone that is interested in growing blueberries, even if you only have one bush. Annual dues are $20
On this web site, you can find a [list](member_list.html) and a [map](member_map.html) with locations of blueberry farms in Massachusetts.
Fall 2017 meeting
growers panel with moderator Elizabeth Garofalo (Mass Coop Extension) during the farmer-2-farmer session at the 2017 annual meeting | Next seminar:
N**ovember 5th 2023**
Wrentham Senior Center
400 Taunton Street
Wrentham, MA
**speaker:**Mary Conclin
*How to successfully grow blueberries
while dealing with climate change*
**agenda:**
**12:30** Light Italian buffet lunch ($20/ea)
**1:30** Annual business meeting
**2:00** Presentation
**3:15** Hands-on pruning demo at
Gianetti's Blueberry Farm
557 Union Street
Franklin, MA
(9 minutes from the Franklin
Senior Center)
Please **RSVP** before November
[Elisabeth Patt](mailto:eap1226@aol.com?subject=RSVP MCBGA 2016 summer meeting)
|
|
| | | | | | |
| --- | --- | --- | --- | --- | --- |
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<title>Tiny Tim DTL Computer</title>
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<P ALIGN="center"><img src="Tiny Tim Logo.PNG" width="247" height="104" border="0"></P>
<P ALIGN="center"><A HREF="http://www.northdownfarm.co.uk/rory/tim/">Homepage</A></P>
<P ALIGN="left"><a href="http://www.northdownfarm.co.uk/rory/tim/tim-8.htm">TIM 8</a> is all good, but writing
programs takes ages as they have to be printed out in stages. Then if there's a mistake you have
to print it all out again. Since I had started to write more and more
complex programs (Euclid's algorithm, solving simultaneous equations,
etc.) it was becoming almost impossible, and these programs have so
far only have been successfully run on my simulator.</P>
<P ALIGN="left">What I needed was a stored program computer, which was
fast and had plenty of memory. I got fairly good at designing relay
logic, but that is realistically not a very useful area to be an
expert in. Besides the TIM project is all about learning new skills,
and relay logic is no longer a new skill to me. So I've decided to
come forward about 30 years in my computer design.</P>
<P ALIGN="left">Obviously, building a computer out of IC's is too easy.
There are several around, and it's a fairly well established science.
However I noticed there was a distinct lack of <A HREF="http://en.wikipedia.org/wiki/Diodetransistor_logic">Diode-Transistor
Logic</A> (or DTL) computers, historical or otherwise. There was probably a good reason for this, but I have decided to try and rectify the
problem regardless.</P>
<P ALIGN="left">Transistors and I have never really got on very well;
any project I'd done using transistors had failed miserably unless I
was following a circuit diagram. So this was a good opportunity to
finally learn how to use them for something other than
producing smoke.</P>
<P ALIGN="left">As this is quite a large project, I've split it into sections:</P>
<P ALIGN="center"><a href="http://www.northdownfarm.co.uk/rory/tim/research.htm">Research</a></P>
<P ALIGN="center"><a href="http://www.northdownfarm.co.uk/rory/tim/testing.htm">Prototyping and Testing</a></P>
<P ALIGN="center"><a href="http://www.northdownfarm.co.uk/rory/tim/specification.htm">Specification</a></P>
<P ALIGN="center"><a href="http://www.northdownfarm.co.uk/rory/tim/construction.htm">Construction</a></P>
<P ALIGN="center"> </P>
<P ALIGN="left">For videos on the project, visit <a href="http://www.youtube.com/user/rapidrory">http://www.youtube.com/user/rapidrory</a></P>
<P ALIGN="left">Both the project and this site are still a work in
progress, so check back here for updates. Last update was on 12/03/13</P>
<P ALIGN="center"><A HREF="http://www.northdownfarm.co.uk/rory/tim/">Homepage</A>
</P>
<!-- ========================================== -->
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<p/>
<center>JavaScript by <a href="mailto:qirien@earthling.net">Qirien Dhaela</a></center>
<p/>
<h3>Join the ring?</h3>
To join the Homebuilt CPUs ring, drop me <a href="mailto:daveb@iinet.net.au">a line</a>,
mentioning your page's URL. I'll then add it to the list.
<br/>
You will need to copy this code fragment into your page. <br/>
<i>Note</i>: The ring is chartered for projects that include a home-built
CPU. It can emulate a commercial part, that′s OK. But actually using that
commercial CPU doesn′t rate. Likewise, the project must have been
at least partially built: pure paper designs don′t rate either. It can be built using any technology
you like, from relays to FPGAs.
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Tiny Tim DTL Computer
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![](Tiny Tim Logo.PNG)
[Homepage](http://www.northdownfarm.co.uk/rory/tim/)
[TIM 8](http://www.northdownfarm.co.uk/rory/tim/tim-8.htm) is all good, but writing
programs takes ages as they have to be printed out in stages. Then if there's a mistake you have
to print it all out again. Since I had started to write more and more
complex programs (Euclid's algorithm, solving simultaneous equations,
etc.) it was becoming almost impossible, and these programs have so
far only have been successfully run on my simulator.
What I needed was a stored program computer, which was
fast and had plenty of memory. I got fairly good at designing relay
logic, but that is realistically not a very useful area to be an
expert in. Besides the TIM project is all about learning new skills,
and relay logic is no longer a new skill to me. So I've decided to
come forward about 30 years in my computer design.
Obviously, building a computer out of IC's is too easy.
There are several around, and it's a fairly well established science.
However I noticed there was a distinct lack of [Diode-Transistor
Logic](http://en.wikipedia.org/wiki/Diodetransistor_logic) (or DTL) computers, historical or otherwise. There was probably a good reason for this, but I have decided to try and rectify the
problem regardless.
Transistors and I have never really got on very well;
any project I'd done using transistors had failed miserably unless I
was following a circuit diagram. So this was a good opportunity to
finally learn how to use them for something other than
producing smoke.
As this is quite a large project, I've split it into sections:
[Research](http://www.northdownfarm.co.uk/rory/tim/research.htm)
[Prototyping and Testing](http://www.northdownfarm.co.uk/rory/tim/testing.htm)
[Specification](http://www.northdownfarm.co.uk/rory/tim/specification.htm)
[Construction](http://www.northdownfarm.co.uk/rory/tim/construction.htm)
For videos on the project, visit <http://www.youtube.com/user/rapidrory>
Both the project and this site are still a work in
progress, so check back here for updates. Last update was on 12/03/13
[Homepage](http://www.northdownfarm.co.uk/rory/tim/)
## Homebuilt CPUs WebRing
JavaScript by [Qirien Dhaela](mailto:qirien@earthling.net)
### Join the ring?
To join the Homebuilt CPUs ring, drop me [a line](mailto:daveb@iinet.net.au),
mentioning your page's URL. I'll then add it to the list.
You will need to copy this code fragment into your page.
*Note*: The ring is chartered for projects that include a home-built
CPU. It can emulate a commercial part, that′s OK. But actually using that
commercial CPU doesn′t rate. Likewise, the project must have been
at least partially built: pure paper designs don′t rate either. It can be built using any technology
you like, from relays to FPGAs.
| http://www.northdownfarm.co.uk/rory/tim/tinytim.htm |
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<html xmlns="http://www.w3.org/1999/xhtml">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
<meta name="Description" content="Amalfi, côte amalfitaine, costiera amlfitana, voyage en Campanie, Campania, golfo di Salerno" />
<title>Amalfi</title>
<script type="text/javascript" src="../jquery-1.2.6.js"></script>
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<p align="center"><img src="../photos/amalfi/giudizio_title.gif" width="400" height="294" /></p>
<table width="100%" border="0" cellspacing="0">
<tr>
<td><span class="style2"><span class="style3">Le jour du jugement dernier, pour les amalfitains qui entreront au paradis, <br />
ce sera un jour comme tous les autres</span>.<br />
<span class="style3">On Judgment Day, for the Amalfitans who will enter Paradise, it will be a day like any other.</span></span></td>
</tr>
<tr>
<td height="37"><p> </p>
<p> </p></td>
</tr>
<tr>
<td>Amalfi est le principal joyaux de la Côte amalfitaine, entre Sorrento et Salerno, sur le Golfe de Salerne.</td>
</tr>
</table>
<p> </p>
<table width="100%" cellspacing="0">
<tr>
<td><div align="center"><a href="../photos/amalfi/amalfi1.jpg" title="On arrive à Amalfi" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi1.jpg" alt="On arrive à Amalfi" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi2.jpg" title="On se rapproche d'Amalfi" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi2.jpg" alt="On se rapproche d'Amalfi" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi3.jpg" title="Amalfi" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi3.jpg" alt="Amalfi" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/giudizio.jpg" title="Il Giorno del Giudizio..." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_giudizio.jpg" alt="Il Giorno del Giudizio..." border="0" /></a></div></td>
</tr>
<tr valign="top">
<td height="40"><div align="center">A l'approche d'Amalfi...</div></td>
<td><div align="center">Encore plus proche...</div></td>
<td><div align="center">On y est...</div></td>
<td><div align="center">Sagesse et espoir</div></td>
</tr>
<tr>
<td><div align="center"><a href="../photos/amalfi/amalfi4.jpg" title="Face au port..." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi4.jpg" alt="Face au port..." border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi5.jpg" title="Amalfi" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi5.jpg" alt="Amalfi" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi7.jpg" title="La plage..." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi7.jpg" alt="La plage..." border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi8.jpg" title="Vue de la corniche" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi8.jpg" alt="Vue de la corniche" border="0" /></a></div></td>
</tr>
<tr valign="top">
<td height="34">Sur le port...</td>
<td>Un musée...???</td>
<td>La plage vue de la corniche</td>
<td>La corniche, la plage, Amalfi...</td>
</tr>
<tr>
<td height="19"> </td>
<td> </td>
<td> </td>
<td> </td>
</tr>
<tr>
<td><div align="center"><a href="../photos/amalfi/amalfi6.jpg" title="La tour de guet au bout de la corniche..." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi6.jpg" alt="La tour de guet au bout de la corniche..." border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/cinq_mats2.jpg" title="Un 'cinq-mats' Ã l'ancre..." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_cinq_mats2.jpg" alt="Un 'cinq-mats' Ã l'encre.." border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/cinq_mats1.jpg" title="Un 'cinq-mats' Ã l'encre.." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_cinq_mats1.jpg" alt="Un 'cinq-mats' Ã l'ancre.." border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi19.jpg" title="Amalfi" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi19.jpg" alt="Amalfi" border="0" /></a></div></td>
</tr>
<tr valign="top">
<td height="32">Tour de guet sarazinne sur<br />
la corniche</td>
<td>Cinq-mats à l'ancre</td>
<td>Cinq-mats à l'ancre</td>
<td>Amalfi</td>
</tr>
<tr>
<td height="19"> </td>
<td> </td>
<td> </td>
<td> </td>
</tr>
<tr>
<td><div align="center"><a href="../photos/amalfi/amalfi.jpg" title="Amalfi vue de la corniche..." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi.jpg" alt="Amalfi vue de la corniche..." border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi18.jpg" title="Amalfi et l'autre corniche..." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi18.jpg" alt="Amalfi et l'autre corniche..." border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi17.jpg" title="Amalfi et l'autre corniche...." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi17.jpg" alt="Amalfi et l'autre corniche..." border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/past_amalfi_east.jpg" title="En quittant Amalfi vers l'est..." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_past_amalfi_east.jpg" alt="En quittant Amalfi vers l'est..." border="0" /></a></div></td>
</tr>
<tr valign="top">
<td height="40">La corniche, la plage, Amalfi...</td>
<td>L'autre corniche <br />
vu du port.</td>
<td>L'autre corniche <br />
vu du port.</td>
<td>En sortant d'Amalfi <br />
vers l'Est.</td>
</tr>
<tr>
<td height="19"> </td>
<td> </td>
<td> </td>
<td> </td>
</tr>
<tr>
<td><div align="center"><a href="../photos/amalfi/amalfi_duomo4.jpg" title="Le Duomo, la Cathédrale" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi_duomo4.jpg" alt="Le Duomo, la Cathédrale" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi_duomo3.jpg" title="Le Duomo, la Cathédrale" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi_duomo3.jpg" alt="Le Duomo, la Cathédrale" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi_duomo2.jpg" title="Le Duomo, la Cathédrale" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi_duomo2.jpg" alt="Le Duomo, la Cathédrale" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi_duomo1.jpg" title="Le Duomo, la Cathédrale" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi_duomo1.jpg" alt="Le Duomo, la Cathédrale" border="0" /></a></div></td>
</tr>
<tr valign="top">
<td height="33">Le Duomo, la cathédrale d'Amalfi</td>
<td>Duomo</td>
<td>Duomo</td>
<td>La place du Duomo...</td>
</tr>
<tr>
<td height="19"> </td>
<td> </td>
<td> </td>
<td> </td>
</tr>
<tr>
<td> </td>
<td> </td>
<td> </td>
<td> </td>
</tr>
<tr>
<td><div align="center"><a href="../photos/amalfi/amalfi20.jpg" title="Passage vouté" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi20.jpg" alt="Passage vouté" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi14.jpg" title="Escalier" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi14.jpg" alt="Escalie" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi15.jpg" title="Ruelle" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi15.jpg" alt="Ruelle" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi16.jpg" title="Porte et colonnades" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi16.jpg" alt="Porte et colonnades" border="0" /></a></div></td>
</tr>
<tr valign="top">
<td height="46">Un passage sous <br />
la voute...</td>
<td>Un escalier</td>
<td>Une ruelle</td>
<td>Une porte et des colonnes <br />
au bout d'une ruelle...</td>
</tr>
<tr>
<td height="19"> </td>
<td> </td>
<td> </td>
<td> </td>
</tr>
<tr>
<td><div align="center"><a href="../photos/amalfi/amalfi21.jpg" title="Porte et colonnades" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi21.jpg" alt="Porte et colonnades" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi22.jpg" title="Passage vouté" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi22.jpg" alt="Passage vouté" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi23.jpg" title="Ruelle" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi23.jpg" alt="Ruelle" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi9.jpg" title="Une ruelle sombre..." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi9.jpg" alt="Ruelle" border="0" /></a></div></td>
</tr>
<tr valign="top">
<td height="27">Porte et colonnades</td>
<td>Escalier</td>
<td>Ruelle en escalier</td>
<td>Ruelle sombre</td>
</tr>
<tr>
<td height="39"> </td>
<td> </td>
<td> </td>
<td> </td>
</tr>
<tr>
<td><div align="center"><a href="../photos/amalfi/amalfi13.jpg" title="Fontaine et piazza" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi13.jpg" alt="Fontaine et piazza" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi12.jpg" title="Une rue en escalier, une autre...!!!" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi12.jpg" alt="Escalier" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi11.jpg" title="Encore un escalier!!" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi11.jpg" alt="Encore un escalier!" border="0" /></a></div></td>
<td><div align="center"><a href="../photos/amalfi/amalfi10.jpg" title="Un escalier..." class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_amalfi10.jpg" alt="Un escalier..." border="0" /></a></div></td>
</tr>
<tr valign="top">
<td height="25">Fontaine et marches</td>
<td>Marches...</td>
<td>Un autre escalier!!!</td>
<td>Encore un escalier!!!</td>
</tr>
<tr>
<td height="19"> </td>
<td> </td>
<td> </td>
<td> </td>
</tr>
<tr>
<td> </td>
<td colspan="2"><div align="center"><a href="../photos/amalfi/ibsen_wagner_plaque.jpg" title="Ibsen et Wagner ont dormi ici!!!" class="thickbox" rel="gallery"><img src="../photos/amalfi/thumbs/tn_ibsen_wagner_plaque.jpg" alt="Ibsen et Wagner ont dormi ici!!!" border="0" /></a></div>
</td>
<td> </td>
</tr>
<tr>
<td> </td>
<td colspan="2" valign="top">Ibsen et Wagner à Amalfi</td>
<td> </td>
</tr>
</table>
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| Le jour du jugement dernier, pour les amalfitains qui entreront au paradis,
ce sera un jour comme tous les autres.
On Judgment Day, for the Amalfitans who will enter Paradise, it will be a day like any other. |
|
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| Amalfi est le principal joyaux de la Côte amalfitaine, entre Sorrento et Salerno, sur le Golfe de Salerne. |
| | | | |
| --- | --- | --- | --- |
| [On arrive à Amalfi](../photos/amalfi/amalfi1.jpg "On arrive à Amalfi") | [On se rapproche d'Amalfi](../photos/amalfi/amalfi2.jpg "On se rapproche d'Amalfi") | [Amalfi](../photos/amalfi/amalfi3.jpg "Amalfi") | [Il Giorno del Giudizio...](../photos/amalfi/giudizio.jpg "Il Giorno del Giudizio...") |
| A l'approche d'Amalfi... | Encore plus proche... | On y est... | Sagesse et espoir |
| [Face au port...](../photos/amalfi/amalfi4.jpg "Face au port...") | [Amalfi](../photos/amalfi/amalfi5.jpg "Amalfi") | [La plage...](../photos/amalfi/amalfi7.jpg "La plage...") | [Vue de la corniche](../photos/amalfi/amalfi8.jpg "Vue de la corniche") |
| Sur le port... | Un musée...??? | La plage vue de la corniche | La corniche, la plage, Amalfi... |
| | | | |
| [La tour de guet au bout de la corniche...](../photos/amalfi/amalfi6.jpg "La tour de guet au bout de la corniche...") | [Un 'cinq-mats' Ã l'encre..](../photos/amalfi/cinq_mats2.jpg "Un 'cinq-mats' Ã l'ancre...") | [Un 'cinq-mats' Ã l'ancre..](../photos/amalfi/cinq_mats1.jpg "Un 'cinq-mats' Ã l'encre..") | [Amalfi](../photos/amalfi/amalfi19.jpg "Amalfi") |
| Tour de guet sarazinne sur
la corniche | Cinq-mats à l'ancre | Cinq-mats à l'ancre | Amalfi |
| | | | |
| [Amalfi vue de la corniche...](../photos/amalfi/amalfi.jpg "Amalfi vue de la corniche...") | [Amalfi et l'autre corniche...](../photos/amalfi/amalfi18.jpg "Amalfi et l'autre corniche...") | [Amalfi et l'autre corniche...](../photos/amalfi/amalfi17.jpg "Amalfi et l'autre corniche....") | [En quittant Amalfi vers l'est...](../photos/amalfi/past_amalfi_east.jpg "En quittant Amalfi vers l'est...") |
| La corniche, la plage, Amalfi... | L'autre corniche
vu du port. | L'autre corniche
vu du port. | En sortant d'Amalfi
vers l'Est. |
| | | | |
| [Le Duomo, la Cathédrale](../photos/amalfi/amalfi_duomo4.jpg "Le Duomo, la Cathédrale") | [Le Duomo, la Cathédrale](../photos/amalfi/amalfi_duomo3.jpg "Le Duomo, la Cathédrale") | [Le Duomo, la Cathédrale](../photos/amalfi/amalfi_duomo2.jpg "Le Duomo, la Cathédrale") | [Le Duomo, la Cathédrale](../photos/amalfi/amalfi_duomo1.jpg "Le Duomo, la Cathédrale") |
| Le Duomo, la cathédrale d'Amalfi | Duomo | Duomo | La place du Duomo... |
| | | | |
| | | | |
| [Passage vouté](../photos/amalfi/amalfi20.jpg "Passage vouté") | [Escalie](../photos/amalfi/amalfi14.jpg "Escalier") | [Ruelle](../photos/amalfi/amalfi15.jpg "Ruelle") | [Porte et colonnades](../photos/amalfi/amalfi16.jpg "Porte et colonnades") |
| Un passage sous
la voute... | Un escalier | Une ruelle | Une porte et des colonnes
au bout d'une ruelle... |
| | | | |
| [Porte et colonnades](../photos/amalfi/amalfi21.jpg "Porte et colonnades") | [Passage vouté](../photos/amalfi/amalfi22.jpg "Passage vouté") | [Ruelle](../photos/amalfi/amalfi23.jpg "Ruelle") | [Ruelle](../photos/amalfi/amalfi9.jpg "Une ruelle sombre...") |
| Porte et colonnades | Escalier | Ruelle en escalier | Ruelle sombre |
| | | | |
| [Fontaine et piazza](../photos/amalfi/amalfi13.jpg "Fontaine et piazza") | [Escalier](../photos/amalfi/amalfi12.jpg "Une rue en escalier, une autre...!!!") | [Encore un escalier!](../photos/amalfi/amalfi11.jpg "Encore un escalier!!") | [Un escalier...](../photos/amalfi/amalfi10.jpg "Un escalier...") |
| Fontaine et marches | Marches... | Un autre escalier!!! | Encore un escalier!!! |
| | | | |
| | [Ibsen et Wagner ont dormi ici!!!](../photos/amalfi/ibsen_wagner_plaque.jpg "Ibsen et Wagner ont dormi ici!!!") | |
| | Ibsen et Wagner à Amalfi | |
| |
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<h1>Harvard College Observatory History in Images</h1>
<div class=mytext>
This is a personal project collecting and documenting early images of Harvard College Observatory, focusing on the site at Observatory Hill (previously Summer House Hill). Buildings, instruments, people, and observations.
<p>
Disclaimer: all content here is solely my own views, and in no way represents the views of my employer, or anyone else. Also, I'm documenting things as I learn about them, so expect frequent errors. Corrections will occur without notice and without a changelog at this point.
<p>
</div>
<span class=topic>computers</span>
<p>
<p>
This page shows a list of all images tagged with "computers".
<p>
<p>
<table class=imagetable>
<tr>
<td><a href="images/ComputersDraperPose.jpg"><img src="thumbs/ComputersDraperPose.png"></a></td>
<td>
<a href="#ComputersDraperPose" name="ComputersDraperPose"><span class=linky>[link]</span></a><b>1891 </b><p>
<b>Earliest source:</b> "[Observatory women computers], 1891." <i>Harvard University Archives / HUV 1210 (9-3).</i> Harvard Libraries, <sup><a href="references.html#olvwork289691">olvwork289691</a></sup>
<p>
A group photo of computers at Harvard together with Mary Anna Palmer Draper, aka Mrs. Henry Draper. She's seated in the middle. After her husband's death, she contributed a significant sum of money to continue her late husbands' dream of scientific astrophotograpy, leading to the Draper Catalog, an ambitious project of the Observatory. Many, though not all, computers were funded for this project.
<p>
Harvard dates this as 1891. It seems to be approximately the same time as other photos with similar groups of women, taken in the same room. I think there were two pairs of photos taken on different days.
<p>
The photo was taken in the long computing room (see 1876 floor plans) on the south side of the second floor (the top floor, excluding the dome) of the building. The photograph was taken facing east, and the doorway in the photo is the closet shown in the floor plan.
<p>
Left to right: <li>unknown (standing) <li>unknown (seated) <li>possibly Eve Leland <li>Mrs. Draper (seated) <li>Antonia Maury <li>Williamina Fleming <li>possibly Mabel C. Stevens (or some other Stevens) <li>probably Florence Cushman <li>unknown
<p>
Note that Stevens is Mrs. Fleming's maiden name, and she did have other relatives in Boston, but so far I don't know if any of the other Stevens that worked at the Observatary are related.
<p>
[Observatory women computers], 1891
<p>
1891
<p>
<em>General:</em> The women depicted in this photograph analyized stellar photographs and computed data at the Harvard College Observatory.
<p>
</td>
</tr>
<tr>
<td><a href="images/ComputersDraperReading.jpg"><img src="thumbs/ComputersDraperReading.png"></a></td>
<td>
<a href="#ComputersDraperReading" name="ComputersDraperReading"><span class=linky>[link]</span></a><b>1891 </b><p>
<b>Earliest source:</b> "Observatory girls with Mrs. Draper, 1891<br/><em>Alternate Title:</em> [Observatory computer room and staff], 1891." <i>Harvard University Archives / HUV 1210 (9-5).</i> Harvard Libraries, <sup><a href="references.html#olvwork289692">olvwork289692</a></sup>
<p>
Another photograph taken in the same place and on the same day as the previous, with the same people.
<p>
</td>
</tr>
<tr>
<td><a href="images/ComputersWithoutPickeringWiki.jpg"><img src="thumbs/ComputersWithoutPickeringWiki.png"></a></td>
<td>
<a href="#ComputersWithoutPickeringWiki" name="ComputersWithoutPickeringWiki"><span class=linky>[link]</span></a><b>1891 </b><p>
Computers in one of the computing rooms at the Observatory. Harvard's date of 1891 for this photo is probably pretty accurate. It has to be after Dec. 1889, based on the graph on the wall of β Aurigӕ, just behind Antonia Maury (who is credited for discovering that it is a binary star). And as it was published in an April 1892 New England Magazine, thta's the upper limit on the photo.
<p>
This is the same location as the photos with Mrs. Draper and some of the computers, the larger computing room on the top floor of the west wing of the Observatory.
<p>
From left to right: <li>possibly Mabel Stevens <li>unknown <li>Antonia Maury <li>possibly Eve Leland (seated) <li>Williamina Fleming <li>unknown <li>unknown <li>probably Florence Cushman
<p>
</td>
</tr>
<tr>
<td><a href="images/ComputersWithPickering.jpg"><img src="thumbs/ComputersWithPickering.png"></a></td>
<td>
<a href="#ComputersWithPickering" name="ComputersWithPickering"><span class=linky>[link]</span></a><b>1891 </b><p>
<b>Earliest source:</b> "[Observatory computer room and staff], 1891." <i>Harvard University Archives / HUV 1210 (9-4).</i> Harvard Libraries, <sup><a href="references.html#olvwork289689">olvwork289689</a></sup>
<p>
Nearly the identical photo as the previous, but with Pickering added standing on the left. Obviously taken the same day.
<p>
Note that the women did not work <i>this</i> closely. As can be seen in the above photos with Mrs. Draper, the room is larger and they are crowded together for sake of the photograph. There were between three and five rooms total for the computing work, and by my best guess about 15 women worked there at that time, as well as at least five men. Still cramped, but not this cramped.
<p>
The following year, a brick building was constructed to help out with the space issues.
<p>
</td>
</tr>
<tr>
<td><a href="images/TwoWomenComputers.jpg"><img src="thumbs/TwoWomenComputers.png"></a></td>
<td>
<a href="#TwoWomenComputers" name="TwoWomenComputers"><span class=linky>[link]</span></a><b>1891 </b><p>
<b>Earliest source:</b> "Observatory [analysis of stellar spectra], 1891." <i>Harvard University Archives / HUV 1210 (9-6).</i> Harvard Libraries, <sup><a href="references.html#olvwork289693">olvwork289693</a></sup>
<p>
Date is from Harvard
<p>
I think this is Williamina Fleming, seated on the right. The woman on the left may be Mabel C. Stevens, and she's wearing the same dress as one of the women of women computers in the old building with Fleming. Fleming appears to be wearing the same dress also, but without the jacket.
<p>
This photo was taken on the same floor as that other photo, but in a the other computer room at the oppisite side of the building.
<p>
</td>
</tr>
<tr>
<td><a href="images/AJCRadcliffe.jpg"><img src="thumbs/AJCRadcliffe.png"></a></td>
<td>
<a href="#AJCRadcliffe" name="AJCRadcliffe"><span class=linky>[link]</span></a><b>1896ish Annie Jump Cannon while at Radcliffe</b><p>
<b>Earliest source:</b> "Portrait of Annie Jump Cannon." <i>Radcliffe College Archives / PC 70-1-2.</i> Harvard Libraries, <sup><a href="references.html#olvwork353777">olvwork353777</a></sup>
<p>
The earliest image I've found so far of Annie Jump Cannon. This is what Harvard says: "Inscription: Verso: Miss Annie Jump Cannon of the Harvard observatory, taken while doing graduate work at Radcliffe College", and dates it 1895-1897. This would put her at about 33 years old. She had taken ten years off for lack of available work between Wellesley and Radcliffe. During this she took up photography, published a small book of photographs<sup><a href="references.html#footsteps">footsteps</a></sup>, caught scarlet fever, and lost most of her hearing.<sup><a href="references.html#wikicannon">wikicannon</a></sup>
<p>
<p>
I have a small suspicion based on her appearance in other photos that this photo may be much earlier than Harvard's 1896 date, but so far nothing to back it up.
<p>
<p><b>Use/Copyright:</b> Radcliffe College Archives: This image may not be reproduced or transmitted in any form or by any means, electronic or mechanical, without permission in writing from the Radcliffe Archives.
</td>
</tr>
<tr>
<td><a href="images/ComputersBrickBuilding.jpg"><img src="thumbs/ComputersBrickBuilding.png"></a></td>
<td>
<a href="#ComputersBrickBuilding" name="ComputersBrickBuilding"><span class=linky>[link]</span></a><b>1898/3 </b><p>
<b>Earliest source:</b> "[Observatory data analysis by women computers] ." <i>Harvard University Archives / UAV 630.271 (E4116).</i> Harvard Libraries, <sup><a href="references.html#olvwork432388">olvwork432388</a></sup>
<p>
Women computers working (or posing as if they're working) in a room in the new brick building, built in 1892.
<p>
I've dated this photo to March of 1898 based on a calendar visible in the image. The year is not actually legible, but it's a year in which the first was a Tuesday. It also appears (not very clearly) as if the calendar is marked with quarter moon phases, and based on this interpretation, it can only be 1898.
<p>
Williamina Fleming is standing. Immediatly in front of her are Eve Leland (back row center) and Ida Woods to the right. The rest are unidentified, although the woman closest to the camera could be A. J. Cannon.
<p>
Note: Harvard identifies this as a photo including Henrietta Leavitt. She does not appear in this photo.
<p>
</td>
</tr>
<tr>
<td><a href="images/WomenOnMinia.jpg"><img src="thumbs/WomenOnMinia.png"></a></td>
<td>
<a href="#WomenOnMinia" name="WomenOnMinia"><span class=linky>[link]</span></a><b>1900ish </b><p>
<b>Earliest source:</b> "[Women on-board ship, ca. 1900]." <i>Harvard University Archives / UAV 630.271 (173).</i> Harvard Libraries, <sup><a href="references.html#olvwork431825">olvwork431825</a></sup>
<p>
A group of women, most or all computers from the Observatory, on board the C.S. Minia, a cable repair ship. On the early end for possible dates of this picture, Mabel Gill (holding Fleming's hand) was hired in 1892 (assuming she had been hired at this point). At the other end, Fleming passed away in 1911.
<p>
The Minia became famous as one of two ships primarily responsible for picking up survivors (and bodies) after the sinking of the Titanic in 1912. Before that, the Minia was a well-known ship under Captain Trott, also well-known for his ability to find and repair broken transatlantic telegram cables, in the deepest seas and the worst weather. He was also known for his hospitality when in port, and this photo could simply have been an opportunity to visit the ship, although he is not one of the gentlemen in this picture.
<p>
William Squares DeCarteret took over as captain in 1899 after Trott passed away, and James Adams became his chief officer. In her 1900 journal, Williamina Fleming specifically mentions a letter from "Captain Adams" about the Minia. James Adams did eventually become captain of the Minia but it seems to be at a later date. At any rate, Miss Fleming apparently had some direct connection with an officer on the ship.
<p>
Another possible connection would be the Observatory's early interest in telegraphy; they might have had much more direct contact with the ship than your average telegraph customer. Transatlantic cables were used for clock synchronization and precise longitude determinations from the very beginning. In 1873, Joseph Lovering published <i>On the Determination of Transatlantic Longitudes by Means of the Telegraphic Cables</i>.
<p>
Also, Captain Trott and at least one crewman were members of the Nova Scotia Institute of Science, which sent their proceedings to the Observatory, so it's possible there were other connections between this ship and the Observatory also.
<p>
Left to right: <li>probably William Squares De Carteret * <li>unknown man <li>unknown woman <li>Mabel Gill <li>unknown woman <li>unknown man <li>Williamina Fleming <li>probably Florence Cushman <li> either Mabel Stevens or A J Cannon** <li>unknonwn woman <li>probably James Adams * <li>probably Eve Leland <li>possibly Ida Woods
<p>
*I found photos of both captain De Carteret and Adams, and I think it's at least possible that these men are those men, but I may have them reversed as they look like brothers to me.
<p>
**I think it looks more like Cannon, and I want it to be her because I actually have no other images (besides very large group shots at conferences) with Fleming and Cannon together. BUT, reasonable estimates of this photo's date would put Cannon in the 35 to 40 range. If this is her she certainly looks MUCH younger than the 1902 photo I have of her.
<p>
</td>
</tr>
<tr>
<td><a href="images/FlemingNewStacks.jpg"><img src="thumbs/FlemingNewStacks.png"></a></td>
<td>
<a href="#FlemingNewStacks" name="FlemingNewStacks"><span class=linky>[link]</span></a><b>1902+ </b><p>
<b>Earliest source:</b> "[Williamina Fleming at Harvard College Observatory plate stacks, ca. 1900]." <i>Harvard University Archives / UAV 630.271 (388).</i> Harvard Libraries, <sup><a href="references.html#olvwork432040">olvwork432040</a></sup>
<p>
Williamina Fleming at Harvard College Observatory plate stacks. These are the "new" plate stacks in the brick building addition, built in 1902.
<p>
</td>
</tr>
<tr>
<td><a href="images/WomenComputers1910.jpg"><img src="thumbs/WomenComputers1910.png"></a></td>
<td>
<a href="#WomenComputers1910" name="WomenComputers1910"><span class=linky>[link]</span></a><b>1911 Women Computers</b><p>
<b>Earliest source:</b> "Observatory Group [photographic group portrait, ca. 1910]." <i>Harvard University Archives / HUPSF Observatory (14).</i> Harvard Libraries, <sup><a href="references.html#olvwork360662">olvwork360662</a></sup>
<p>
Harvard calls this photo "Observatory Group", ca. 1910. The Internet often calls it a photo of "Pickering's Harem". I think it's from mid-1911. The lack of Williamina Fleming certainly makes it likely to be after 1911 when she passed away, and Henrietta Leavitt, also absent from the photo, was out of town until late 1911. The photo was taken in the front of the Astrophotographic Library aka, the "Brick Building", aka "Building C."
<p>
"Pickering's Harem" may be a modern sexist invention rather than a historic one. I've found no references earlier than 1976 for this phrase. On the other hand, they were much more polite about what the wrote down back then, so it may just as well be a real nickname passed down by oral tradition.
<p>
One source that DOES use that nickname, from 1982, also lists a very detailed description of the women in this photo, which I'll just quote here directly:
<p>
"At the far left of the photograph is Margaret Harwood (AB Radcliffe 1907, MA University of California 1916), who had just completed her first year as Astronomical Fellow at the Maria Mitchell Observatory. She was later appointed director there, the first woman to be appointed director of an independent observatory. Beside her in the back row is Mollie O'Reilly, a computer from 1906 to 1918. Next to Pickering is Edith Gill, a computer since 1889. Then comes Annie Jump Cannon (BA Wellesley 1884), who at that time was about halfway through classifying stellar spectra for the Henry Draper Catalogue. Behind Miss Cannon is Evelyn Leland, a computer from 1889 to 1925. Next is Florence Cushman, a computer since 1888. Behind Miss Cushman is Marion Whyte, who worked for Miss Cannon as a recorder from 1911 to 1913. At the far right of this row is Grace Brooks, a computer from 1906 to 1920. Ahead of Miss Harwood in the front row is Arville Walker (AB Radcliffe 1906), who served as assistant from 1906 until 1922. From 1922 until 1957 she held the position of secretary to Harlow Shapley, who succeeded Pickering as Director. The next woman may be Johanna Mackie, an assistant from 1903 to 1920. She received a gold medal from the American Association of Variable Star Observers (AAVSO) for discovering the first nova in the constellation of Lyra. In front of Pickering is Alta Carpenter, a computer from 1906 to 1920. Next is Mabel Gill, a computer since 1892. And finally, Ida Woods (BA Wellesley 1893), who joined the corps of women computers just after graduation. In 1920 she received the first AAVSO nova medal; by 1927, she had seven bars on it for her discoveries of novae on photographs of the Milky Way."<sup><a href="references.html#pickeringsharem">pickeringsharem</a></sup>
<p>
</td>
</tr>
<tr>
<td><a href="images/PaperDoll.png"><img src="thumbs/PaperDoll.png"></a></td>
<td>
<a href="#PaperDoll" name="PaperDoll"><span class=linky>[link]</span></a><b>1918 Women Computers</b><p>
<b>Earliest source:</b> "[Observatory Staff in "paper doll" pose, (in line holding hands) panoramic photograph ca. 1918]." <i>Harvard University Archives / UAV 630.271 (391).</i> Harvard Libraries, <sup><a href="references.html#olvwork432043">olvwork432043</a></sup>
<p>
From left to right (primary identifications come from Harvard, who says the names were listed on the back):
<p>
<li>Ida Woods<li>Eva Leland<li>Florence Cushman<li>Grace Brooks<li>[Hannah?]; other sources say Mary Van or Mary H. Vann<sup><a href="references.html#sipickwomen">sipickwomen</a></sup> <sup><a href="references.html#neafspectrohist">neafspectrohist</a></sup><li>Henrietta Leavitt<li>Mollie O'Reilly<li>Mabel Gill (or "Edith F. Gill"<sup><a href="references.html#sipickwomen">sipickwomen</a></sup>)<li>Alta Carpenter<li>A.J.C [Annie Jump Cannon]<li>Harvard missed this one; other sources say Dorothy Black or Block<sup><a href="references.html#sipickwomen">sipickwomen</a></sup> <sup><a href="references.html#neafspectrohist">neafspectrohist</a></sup><li>Arville Walker<li>Mr. Hinckley<li>Prof. King.
<p>
<p>
I believe the correct names for two of these are "Mary H. Vann" and "Dorothy Block".<sup><a href="references.html#jaavsoharwood">jaavsoharwood</a></sup> Also, I think this is Mabel, not Edith Gill (or the few other labelled photos I've seen so far similarly mislabel the presumed sisters).
<p>
<p>
For the longest time I didn't know where pictures like this one were taken. This is an addition to the director's residence added in about 1893 that maybe doubled the size of the residence. The building is not curved, and the brick building to the right is the end of the astrophotographic addition, lying in the same plane. The wide angle just makes it look like a 90 degree bend.
<p>
</td>
</tr>
<tr>
<td><a href="images/AsWeWere.jpg"><img src="thumbs/AsWeWere.png"></a></td>
<td>
<a href="#AsWeWere" name="AsWeWere"><span class=linky>[link]</span></a><b>1925 "As We Were"</b><p>
<b>Earliest source:</b> "Observatory Women [photographic group portrait, 1925]." <i>Harvard University Archives / HUPSF Observatory (19).</i> Harvard Libraries, <sup><a href="references.html#olvwork360663">olvwork360663</a></sup>
<p>
Harvard says the caption is "As We Were" in the upper left corner, but they must not have scanned that or it is on the back. This is an amazing photo crossing generations of women at Harvard. It's the end of the era of women computers, and the beginning of the era of women scientists.
<p>
I found a source identifying the names. Ceclia Payne's expanded autobiography.<sup><a href="references.html#paynerecollections">paynerecollections</a></sup> My guesses were all correct (I skipped five of them).
<p>
<p>
Back row:<li>Margaret Harwood<li>Cecilia Payne<li>Arville D. Walker<li>Edith F. Gill
<p>
Middle row:<li>Lillian L. Hodgdon<li>Annie J. Cannon<li>Evelyn F. Leland<li>Ida E. Woods<li>Mabel A. Gill<li>Florence Cushman
<p>
Bottom row:<li>Agnes M. Hoovens<li>Mary B. Howe<li>Harvia H. Wilson<li>Margaret Walton (married name Mayall)<li>Antonia C. Maury
<p>
</td>
</tr>
<tr>
<td><a href="images/WomensWork1925.jpg"><img src="thumbs/WomensWork1925.png"></a></td>
<td>
<a href="#WomensWork1925" name="WomensWork1925"><span class=linky>[link]</span></a><b>1925/05/19 Women Computers and Radcliffe Students</b><p>
<b>Earliest source:</b> Margaret W. Rossiter. ""Women's Work" in Science, 1880-1910." <i>Isis vol. 71 no. 3.</i> University of Chicago Press, September 1980.<sup><a href="references.html#womensworksci">womensworksci</a></sup>
<p>
Unknown location. (Actually I now believe this may be the west wing of the original building, in the transit room, but after the transit instruments were removed). Source says this photo was taken 19 May, 1925.<sup><a href="references.html#pickeringsharem">pickeringsharem</a></sup>
<p>
I've only just now noticed that these women are all wearing the exact same outfits as in the other 1925 photo above "As We Were", and so both photos were probably taken on the same day. They appear to be the same set of women, and based on that I've put in the five names I hadn't figured out.
<p>
My guesses on identity, left to right:
<p>
H. Wilson, A. Maury, A. Hoovens, I. Woods, A. J. Cannon, M. Howe, M. Harwood (on floor), E. Leland, A. Walker, L. Hodgdon, C. Payne (seated), E. F. Gill (standing), M. Walton Mayall, M. Gill, F. Cushman
<p>
</td>
</tr>
<tr>
<td><a href="images/PinaforeCastCrew.png"><img src="thumbs/PinaforeCastCrew.png"></a></td>
<td>
<a href="#PinaforeCastCrew" name="PinaforeCastCrew"><span class=linky>[link]</span></a><b>1929/12/31 Observatory Pinafore Cast and Crew</b><p>
The Cast and Crew of the Observatory Pinafore
<p>
A set of six photos of the Observatory Pinfore has recently turned up. They've been scanned by their owner, Charles Reynes, who's the great grandson of Edward Skinner King (who was almost certainly at the performance - he's in the group photo for the AAS conference where the play was staged). They are by far the best quality images I've found anywhere of the performance, and three of them haven't been found anywhere else.
<p>
I'm having a particular problem with two identifications from these photographs: G. W. Wheelwright as Winslow Upton and W. R. Ransom as Pickering. I'm hoping to identify the characters from the context of the photos, but at this point I'm not sure that will work. From the opposite end, I've attempted to find photographs of both Wheelwright and Ransom in other contexts. Neither seems to look at all like the character in the photos with the more recessed chin.
<p>
<b>Identifications:</b>
<p>
Bart J. Bok, unknown women, unknown man, [Wheelwright or Ransom], unknown woman, Harlow Shapley, [Ransom or Wheelwright], Arville Walker, Peter M. Millman, Arthur R. Sayer, Leon Campbell
<p>
unknown boy, Mildred Shapley, Adelaide Ames, Cecilia Payne (Gaposchkin), Henrietta Swope, Sylvia Mussels (Lindsay), Helen Sawyer (Hogg), unknown boy
<p>
<p><b>Use/Copyright:</b> Copyright held by Charles Reynes, used here with permission
</td>
</tr>
<tr>
<td><a href="images/PinaforeCurtainCall.png"><img src="thumbs/PinaforeCurtainCall.png"></a></td>
<td>
<a href="#PinaforeCurtainCall" name="PinaforeCurtainCall"><span class=linky>[link]</span></a><b>1929/12/31 Observatory Pinafore Curtain Call</b><p>
The cast of the Observatory Pinafore
<p>
<b>Identifications:</b>
<p>
Adelaide Ames (as Rhoda G. Saunders), Bart J. Bok (as Leonard Waldo), Mildred Shapley (as computer), Unknown, Cecilia Payne (as Josephina McCormack), Peter M. Millman (as William Augustus Rogers), Henrietta Swope (as computer), Unknown, Helen Sawyer (as computer), Arthur R. Sayer (as F. E. Seagrave), Sylvia Mussels (as computer), Leon Campbell (as Arthur Searle).
<p>
<p><b>Use/Copyright:</b> Copyright held by Charles Reynes, used here with permission
</td>
</tr>
<tr>
<td><a href="images/PinaforeGun.png"><img src="thumbs/PinaforeGun.png"></a></td>
<td>
<a href="#PinaforeGun" name="PinaforeGun"><span class=linky>[link]</span></a><b>1929/12/31 Observatory Pinafore Don't Shoot</b><p>
A scene in Observatory Pinafore, where Josephina stops Professor Rogers from killing himself in despair over the defection of his helpful assistant, and circle reader, and whatever else.
<p>
This image is the most widely available image of the performance.
<p>
<b>Identifications:</b>
<p>
Peter Millman, Cecilia Payne-Gaposchkin, Henrietta Swope, Mildred Shapley (daughter of Harlow and Martha Shapeley), Helen Sawyer-Hogg, Sylvia Mussells-Lindsay, Adelaide Ames, Leon Campbell.
<p>
These identifications come from the copy of this picture in the Emilo Segre Visual Archive. I've based some of my own identifcations on this list. This is my only source for Mildred Shapley and Sylvia Mussels, all the other faces I've found in other photos (to varying degrees of a satisfactory match, but at least enough of a match to improve my confidence that they're correct).
<p>
<p><b>Use/Copyright:</b> Copyright held by Charles Reynes, used here with permission
</td>
</tr>
<tr>
<td><a href="images/PinaforeTugOWar.png"><img src="thumbs/PinaforeTugOWar.png"></a></td>
<td>
<a href="#PinaforeTugOWar" name="PinaforeTugOWar"><span class=linky>[link]</span></a><b>1929/12/31 Observatory Pinafore - Josephina Tug-of-War</b><p>
A scene from the Observatory Pinafore where Josephina is being pulled away from Professor Rogers by Seagrave and the men of Providence.
<p>
I believe this is the point in the play where Josephina is led to the "dungeon".
<p>
<b>Identifications:</b>
<p>
Unknown, Bart J. Bok, Unknown, Arthur Sayer, Cecilia Payne, Henrietta Swope, Mildred Shapley, Helen Sawyer, Sylvia Mussels, Adelaide Ames.
<p>
<p><b>Use/Copyright:</b> Copyright held by Charles Reynes, used here with permission
</td>
</tr>
<tr>
<td><a href="images/PinaforeWorking.png"><img src="thumbs/PinaforeWorking.png"></a></td>
<td>
<a href="#PinaforeWorking" name="PinaforeWorking"><span class=linky>[link]</span></a><b>1929/12/31 </b><p>
A scene from Observatory Pinfore, with Astronomers and Computers hard at work. Based on the people (and the books), this may be somewhere in the first scene of the play. If so, this could be the Winslow Upton character standing, as the right set of people are on stage for Upton's reciting of "I know the value of a kindly chorus..."
<p>
The portrait of Galileo hanging on the right still <a href="http://hea-www.harvard.edu/~fine/Observatory/_related_GalileoSustermansCarlton.html">hangs in the Observatory today;</a> it is the copy by Carlton gifted in 1890.
<p>
<b>Identifications</b>
<p>
<p><b>Use/Copyright:</b> Copyright held by Charles Reynes, used here with permission
</td>
</tr>
<tr>
<td><a href="images/ComputersWithoutPickering.jpg"><img src="thumbs/ComputersWithoutPickering.png"></a></td>
<td>
<a href="#ComputersWithoutPickering" name="ComputersWithoutPickering"><span class=linky>[link]</span></a><b>Earliest source:</b> "A group of women computers [photographic group portrait, ca. 1900]." <i>Harvard University Archives / HUPSF Observatory (45).</i> Harvard Libraries, <sup><a href="references.html#olvwork360664">olvwork360664</a></sup>
<p>
A group of women computers [photographic group portrait, ca. 1900]
<p>
ca. 1900
<p>
</td>
</tr>
<tr>
<td><a href="images/FlemingDiamond.jpg"><img src="thumbs/FlemingDiamond.png"></a></td>
<td>
<a href="#FlemingDiamond" name="FlemingDiamond"><span class=linky>[link]</span></a><b>Earliest source:</b> "[Williamina P. Fleming, photographic portrait, ca. 1890]<br/><em>Alternate Title:</em> [Fleming, Williamina P., [photographic portrait, ca. 1900]." <i>Harvard University Archives / HUP Fleming, Williamina (1).</i> Harvard Libraries, <sup><a href="references.html#olvwork289681">olvwork289681</a></sup>
<p>
[Williamina P. Fleming, photographic portrait, ca. 1890]<br/><em>Alternate Title:</em> [Fleming, Williamina P., [photographic portrait, ca. 1900]
<p>
ca. 1890
<p>
<em>Historical:</em> Williamina Fleming worked at the Harvard College Observatory. She analyized stellar photographs and computed data.
<p>
</td>
</tr>
<tr>
<td><a href="images/WilliaminaFlemingPhoto.jpg"><img src="thumbs/WilliaminaFlemingPhoto.png"></a></td>
<td>
<a href="#WilliaminaFlemingPhoto" name="WilliaminaFlemingPhoto"><span class=linky>[link]</span></a></td>
</tr>
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At 2020/02/03 22:22<BR><B><A HREF="/~fine/cgi/showit.cgi?method=r&email=4%2B%25u%22v.'%23yTw$%22wu()B%23y)">Pamela Gill Byrne</A></B> wrote:<P>
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Hello! Edith and Mabel Gill were my great aunts. I can identify them for you in these (and other) photos. Would love to be able to see these in person. Is there someplace where these are on display? Thank you so much! <P><P>
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Harvard College Observatory History in Images
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# Harvard College Observatory History in Images
This is a personal project collecting and documenting early images of Harvard College Observatory, focusing on the site at Observatory Hill (previously Summer House Hill). Buildings, instruments, people, and observations.
Disclaimer: all content here is solely my own views, and in no way represents the views of my employer, or anyone else. Also, I'm documenting things as I learn about them, so expect frequent errors. Corrections will occur without notice and without a changelog at this point.
computers
This page shows a list of all images tagged with "computers".
| | |
| --- | --- |
| | [[link]](#ComputersDraperPose)**1891**
**Earliest source:** "[Observatory women computers], 1891." *Harvard University Archives / HUV 1210 (9-3).* Harvard Libraries, [olvwork289691](references.html#olvwork289691)
A group photo of computers at Harvard together with Mary Anna Palmer Draper, aka Mrs. Henry Draper. She's seated in the middle. After her husband's death, she contributed a significant sum of money to continue her late husbands' dream of scientific astrophotograpy, leading to the Draper Catalog, an ambitious project of the Observatory. Many, though not all, computers were funded for this project.
Harvard dates this as 1891. It seems to be approximately the same time as other photos with similar groups of women, taken in the same room. I think there were two pairs of photos taken on different days.
The photo was taken in the long computing room (see 1876 floor plans) on the south side of the second floor (the top floor, excluding the dome) of the building. The photograph was taken facing east, and the doorway in the photo is the closet shown in the floor plan.
Left to right: - unknown (standing) - unknown (seated) - possibly Eve Leland - Mrs. Draper (seated) - Antonia Maury - Williamina Fleming - possibly Mabel C. Stevens (or some other Stevens) - probably Florence Cushman - unknown
Note that Stevens is Mrs. Fleming's maiden name, and she did have other relatives in Boston, but so far I don't know if any of the other Stevens that worked at the Observatary are related.
[Observatory women computers], 1891
1891
*General:* The women depicted in this photograph analyized stellar photographs and computed data at the Harvard College Observatory.
|
| | [[link]](#ComputersDraperReading)**1891**
**Earliest source:** "Observatory girls with Mrs. Draper, 1891*Alternate Title:* [Observatory computer room and staff], 1891." *Harvard University Archives / HUV 1210 (9-5).* Harvard Libraries, [olvwork289692](references.html#olvwork289692)
Another photograph taken in the same place and on the same day as the previous, with the same people.
|
| | [[link]](#ComputersWithoutPickeringWiki)**1891**
Computers in one of the computing rooms at the Observatory. Harvard's date of 1891 for this photo is probably pretty accurate. It has to be after Dec. 1889, based on the graph on the wall of β Aurigӕ, just behind Antonia Maury (who is credited for discovering that it is a binary star). And as it was published in an April 1892 New England Magazine, thta's the upper limit on the photo.
This is the same location as the photos with Mrs. Draper and some of the computers, the larger computing room on the top floor of the west wing of the Observatory.
From left to right: - possibly Mabel Stevens - unknown - Antonia Maury - possibly Eve Leland (seated) - Williamina Fleming - unknown - unknown - probably Florence Cushman
|
| | [[link]](#ComputersWithPickering)**1891**
**Earliest source:** "[Observatory computer room and staff], 1891." *Harvard University Archives / HUV 1210 (9-4).* Harvard Libraries, [olvwork289689](references.html#olvwork289689)
Nearly the identical photo as the previous, but with Pickering added standing on the left. Obviously taken the same day.
Note that the women did not work *this* closely. As can be seen in the above photos with Mrs. Draper, the room is larger and they are crowded together for sake of the photograph. There were between three and five rooms total for the computing work, and by my best guess about 15 women worked there at that time, as well as at least five men. Still cramped, but not this cramped.
The following year, a brick building was constructed to help out with the space issues.
|
| | [[link]](#TwoWomenComputers)**1891**
**Earliest source:** "Observatory [analysis of stellar spectra], 1891." *Harvard University Archives / HUV 1210 (9-6).* Harvard Libraries, [olvwork289693](references.html#olvwork289693)
Date is from Harvard
I think this is Williamina Fleming, seated on the right. The woman on the left may be Mabel C. Stevens, and she's wearing the same dress as one of the women of women computers in the old building with Fleming. Fleming appears to be wearing the same dress also, but without the jacket.
This photo was taken on the same floor as that other photo, but in a the other computer room at the oppisite side of the building.
|
| | [[link]](#AJCRadcliffe)**1896ish Annie Jump Cannon while at Radcliffe**
**Earliest source:** "Portrait of Annie Jump Cannon." *Radcliffe College Archives / PC 70-1-2.* Harvard Libraries, [olvwork353777](references.html#olvwork353777)
The earliest image I've found so far of Annie Jump Cannon. This is what Harvard says: "Inscription: Verso: Miss Annie Jump Cannon of the Harvard observatory, taken while doing graduate work at Radcliffe College", and dates it 1895-1897. This would put her at about 33 years old. She had taken ten years off for lack of available work between Wellesley and Radcliffe. During this she took up photography, published a small book of photographs[footsteps](references.html#footsteps), caught scarlet fever, and lost most of her hearing.[wikicannon](references.html#wikicannon)
I have a small suspicion based on her appearance in other photos that this photo may be much earlier than Harvard's 1896 date, but so far nothing to back it up.
**Use/Copyright:** Radcliffe College Archives: This image may not be reproduced or transmitted in any form or by any means, electronic or mechanical, without permission in writing from the Radcliffe Archives.
|
| | [[link]](#ComputersBrickBuilding)**1898/3**
**Earliest source:** "[Observatory data analysis by women computers] ." *Harvard University Archives / UAV 630.271 (E4116).* Harvard Libraries, [olvwork432388](references.html#olvwork432388)
Women computers working (or posing as if they're working) in a room in the new brick building, built in 1892.
I've dated this photo to March of 1898 based on a calendar visible in the image. The year is not actually legible, but it's a year in which the first was a Tuesday. It also appears (not very clearly) as if the calendar is marked with quarter moon phases, and based on this interpretation, it can only be 1898.
Williamina Fleming is standing. Immediatly in front of her are Eve Leland (back row center) and Ida Woods to the right. The rest are unidentified, although the woman closest to the camera could be A. J. Cannon.
Note: Harvard identifies this as a photo including Henrietta Leavitt. She does not appear in this photo.
|
| | [[link]](#WomenOnMinia)**1900ish**
**Earliest source:** "[Women on-board ship, ca. 1900]." *Harvard University Archives / UAV 630.271 (173).* Harvard Libraries, [olvwork431825](references.html#olvwork431825)
A group of women, most or all computers from the Observatory, on board the C.S. Minia, a cable repair ship. On the early end for possible dates of this picture, Mabel Gill (holding Fleming's hand) was hired in 1892 (assuming she had been hired at this point). At the other end, Fleming passed away in 1911.
The Minia became famous as one of two ships primarily responsible for picking up survivors (and bodies) after the sinking of the Titanic in 1912. Before that, the Minia was a well-known ship under Captain Trott, also well-known for his ability to find and repair broken transatlantic telegram cables, in the deepest seas and the worst weather. He was also known for his hospitality when in port, and this photo could simply have been an opportunity to visit the ship, although he is not one of the gentlemen in this picture.
William Squares DeCarteret took over as captain in 1899 after Trott passed away, and James Adams became his chief officer. In her 1900 journal, Williamina Fleming specifically mentions a letter from "Captain Adams" about the Minia. James Adams did eventually become captain of the Minia but it seems to be at a later date. At any rate, Miss Fleming apparently had some direct connection with an officer on the ship.
Another possible connection would be the Observatory's early interest in telegraphy; they might have had much more direct contact with the ship than your average telegraph customer. Transatlantic cables were used for clock synchronization and precise longitude determinations from the very beginning. In 1873, Joseph Lovering published *On the Determination of Transatlantic Longitudes by Means of the Telegraphic Cables*.
Also, Captain Trott and at least one crewman were members of the Nova Scotia Institute of Science, which sent their proceedings to the Observatory, so it's possible there were other connections between this ship and the Observatory also.
Left to right: - probably William Squares De Carteret \* - unknown man - unknown woman - Mabel Gill - unknown woman - unknown man - Williamina Fleming - probably Florence Cushman - either Mabel Stevens or A J Cannon\*\* - unknonwn woman - probably James Adams \* - probably Eve Leland - possibly Ida Woods
\*I found photos of both captain De Carteret and Adams, and I think it's at least possible that these men are those men, but I may have them reversed as they look like brothers to me.
\*\*I think it looks more like Cannon, and I want it to be her because I actually have no other images (besides very large group shots at conferences) with Fleming and Cannon together. BUT, reasonable estimates of this photo's date would put Cannon in the 35 to 40 range. If this is her she certainly looks MUCH younger than the 1902 photo I have of her.
|
| | [[link]](#FlemingNewStacks)**1902+**
**Earliest source:** "[Williamina Fleming at Harvard College Observatory plate stacks, ca. 1900]." *Harvard University Archives / UAV 630.271 (388).* Harvard Libraries, [olvwork432040](references.html#olvwork432040)
Williamina Fleming at Harvard College Observatory plate stacks. These are the "new" plate stacks in the brick building addition, built in 1902.
|
| | [[link]](#WomenComputers1910)**1911 Women Computers**
**Earliest source:** "Observatory Group [photographic group portrait, ca. 1910]." *Harvard University Archives / HUPSF Observatory (14).* Harvard Libraries, [olvwork360662](references.html#olvwork360662)
Harvard calls this photo "Observatory Group", ca. 1910. The Internet often calls it a photo of "Pickering's Harem". I think it's from mid-1911. The lack of Williamina Fleming certainly makes it likely to be after 1911 when she passed away, and Henrietta Leavitt, also absent from the photo, was out of town until late 1911. The photo was taken in the front of the Astrophotographic Library aka, the "Brick Building", aka "Building C."
"Pickering's Harem" may be a modern sexist invention rather than a historic one. I've found no references earlier than 1976 for this phrase. On the other hand, they were much more polite about what the wrote down back then, so it may just as well be a real nickname passed down by oral tradition.
One source that DOES use that nickname, from 1982, also lists a very detailed description of the women in this photo, which I'll just quote here directly:
"At the far left of the photograph is Margaret Harwood (AB Radcliffe 1907, MA University of California 1916), who had just completed her first year as Astronomical Fellow at the Maria Mitchell Observatory. She was later appointed director there, the first woman to be appointed director of an independent observatory. Beside her in the back row is Mollie O'Reilly, a computer from 1906 to 1918. Next to Pickering is Edith Gill, a computer since 1889. Then comes Annie Jump Cannon (BA Wellesley 1884), who at that time was about halfway through classifying stellar spectra for the Henry Draper Catalogue. Behind Miss Cannon is Evelyn Leland, a computer from 1889 to 1925. Next is Florence Cushman, a computer since 1888. Behind Miss Cushman is Marion Whyte, who worked for Miss Cannon as a recorder from 1911 to 1913. At the far right of this row is Grace Brooks, a computer from 1906 to 1920. Ahead of Miss Harwood in the front row is Arville Walker (AB Radcliffe 1906), who served as assistant from 1906 until 1922. From 1922 until 1957 she held the position of secretary to Harlow Shapley, who succeeded Pickering as Director. The next woman may be Johanna Mackie, an assistant from 1903 to 1920. She received a gold medal from the American Association of Variable Star Observers (AAVSO) for discovering the first nova in the constellation of Lyra. In front of Pickering is Alta Carpenter, a computer from 1906 to 1920. Next is Mabel Gill, a computer since 1892. And finally, Ida Woods (BA Wellesley 1893), who joined the corps of women computers just after graduation. In 1920 she received the first AAVSO nova medal; by 1927, she had seven bars on it for her discoveries of novae on photographs of the Milky Way."[pickeringsharem](references.html#pickeringsharem)
|
| | [[link]](#PaperDoll)**1918 Women Computers**
**Earliest source:** "[Observatory Staff in "paper doll" pose, (in line holding hands) panoramic photograph ca. 1918]." *Harvard University Archives / UAV 630.271 (391).* Harvard Libraries, [olvwork432043](references.html#olvwork432043)
From left to right (primary identifications come from Harvard, who says the names were listed on the back):
- Ida Woods- Eva Leland- Florence Cushman- Grace Brooks- [Hannah?]; other sources say Mary Van or Mary H. Vann[sipickwomen](references.html#sipickwomen) [neafspectrohist](references.html#neafspectrohist)- Henrietta Leavitt- Mollie O'Reilly- Mabel Gill (or "Edith F. Gill"[sipickwomen](references.html#sipickwomen))- Alta Carpenter- A.J.C [Annie Jump Cannon]- Harvard missed this one; other sources say Dorothy Black or Block[sipickwomen](references.html#sipickwomen) [neafspectrohist](references.html#neafspectrohist)- Arville Walker- Mr. Hinckley- Prof. King.
I believe the correct names for two of these are "Mary H. Vann" and "Dorothy Block".[jaavsoharwood](references.html#jaavsoharwood) Also, I think this is Mabel, not Edith Gill (or the few other labelled photos I've seen so far similarly mislabel the presumed sisters).
For the longest time I didn't know where pictures like this one were taken. This is an addition to the director's residence added in about 1893 that maybe doubled the size of the residence. The building is not curved, and the brick building to the right is the end of the astrophotographic addition, lying in the same plane. The wide angle just makes it look like a 90 degree bend.
|
| | [[link]](#AsWeWere)**1925 "As We Were"**
**Earliest source:** "Observatory Women [photographic group portrait, 1925]." *Harvard University Archives / HUPSF Observatory (19).* Harvard Libraries, [olvwork360663](references.html#olvwork360663)
Harvard says the caption is "As We Were" in the upper left corner, but they must not have scanned that or it is on the back. This is an amazing photo crossing generations of women at Harvard. It's the end of the era of women computers, and the beginning of the era of women scientists.
I found a source identifying the names. Ceclia Payne's expanded autobiography.[paynerecollections](references.html#paynerecollections) My guesses were all correct (I skipped five of them).
Back row:- Margaret Harwood- Cecilia Payne- Arville D. Walker- Edith F. Gill
Middle row:- Lillian L. Hodgdon- Annie J. Cannon- Evelyn F. Leland- Ida E. Woods- Mabel A. Gill- Florence Cushman
Bottom row:- Agnes M. Hoovens- Mary B. Howe- Harvia H. Wilson- Margaret Walton (married name Mayall)- Antonia C. Maury
|
| | [[link]](#WomensWork1925)**1925/05/19 Women Computers and Radcliffe Students**
**Earliest source:** Margaret W. Rossiter. ""Women's Work" in Science, 1880-1910." *Isis vol. 71 no. 3.* University of Chicago Press, September 1980.[womensworksci](references.html#womensworksci)
Unknown location. (Actually I now believe this may be the west wing of the original building, in the transit room, but after the transit instruments were removed). Source says this photo was taken 19 May, 1925.[pickeringsharem](references.html#pickeringsharem)
I've only just now noticed that these women are all wearing the exact same outfits as in the other 1925 photo above "As We Were", and so both photos were probably taken on the same day. They appear to be the same set of women, and based on that I've put in the five names I hadn't figured out.
My guesses on identity, left to right:
H. Wilson, A. Maury, A. Hoovens, I. Woods, A. J. Cannon, M. Howe, M. Harwood (on floor), E. Leland, A. Walker, L. Hodgdon, C. Payne (seated), E. F. Gill (standing), M. Walton Mayall, M. Gill, F. Cushman
|
| | [[link]](#PinaforeCastCrew)**1929/12/31 Observatory Pinafore Cast and Crew**
The Cast and Crew of the Observatory Pinafore
A set of six photos of the Observatory Pinfore has recently turned up. They've been scanned by their owner, Charles Reynes, who's the great grandson of Edward Skinner King (who was almost certainly at the performance - he's in the group photo for the AAS conference where the play was staged). They are by far the best quality images I've found anywhere of the performance, and three of them haven't been found anywhere else.
I'm having a particular problem with two identifications from these photographs: G. W. Wheelwright as Winslow Upton and W. R. Ransom as Pickering. I'm hoping to identify the characters from the context of the photos, but at this point I'm not sure that will work. From the opposite end, I've attempted to find photographs of both Wheelwright and Ransom in other contexts. Neither seems to look at all like the character in the photos with the more recessed chin.
**Identifications:**
Bart J. Bok, unknown women, unknown man, [Wheelwright or Ransom], unknown woman, Harlow Shapley, [Ransom or Wheelwright], Arville Walker, Peter M. Millman, Arthur R. Sayer, Leon Campbell
unknown boy, Mildred Shapley, Adelaide Ames, Cecilia Payne (Gaposchkin), Henrietta Swope, Sylvia Mussels (Lindsay), Helen Sawyer (Hogg), unknown boy
**Use/Copyright:** Copyright held by Charles Reynes, used here with permission
|
| | [[link]](#PinaforeCurtainCall)**1929/12/31 Observatory Pinafore Curtain Call**
The cast of the Observatory Pinafore
**Identifications:**
Adelaide Ames (as Rhoda G. Saunders), Bart J. Bok (as Leonard Waldo), Mildred Shapley (as computer), Unknown, Cecilia Payne (as Josephina McCormack), Peter M. Millman (as William Augustus Rogers), Henrietta Swope (as computer), Unknown, Helen Sawyer (as computer), Arthur R. Sayer (as F. E. Seagrave), Sylvia Mussels (as computer), Leon Campbell (as Arthur Searle).
**Use/Copyright:** Copyright held by Charles Reynes, used here with permission
|
| | [[link]](#PinaforeGun)**1929/12/31 Observatory Pinafore Don't Shoot**
A scene in Observatory Pinafore, where Josephina stops Professor Rogers from killing himself in despair over the defection of his helpful assistant, and circle reader, and whatever else.
This image is the most widely available image of the performance.
**Identifications:**
Peter Millman, Cecilia Payne-Gaposchkin, Henrietta Swope, Mildred Shapley (daughter of Harlow and Martha Shapeley), Helen Sawyer-Hogg, Sylvia Mussells-Lindsay, Adelaide Ames, Leon Campbell.
These identifications come from the copy of this picture in the Emilo Segre Visual Archive. I've based some of my own identifcations on this list. This is my only source for Mildred Shapley and Sylvia Mussels, all the other faces I've found in other photos (to varying degrees of a satisfactory match, but at least enough of a match to improve my confidence that they're correct).
**Use/Copyright:** Copyright held by Charles Reynes, used here with permission
|
| | [[link]](#PinaforeTugOWar)**1929/12/31 Observatory Pinafore - Josephina Tug-of-War**
A scene from the Observatory Pinafore where Josephina is being pulled away from Professor Rogers by Seagrave and the men of Providence.
I believe this is the point in the play where Josephina is led to the "dungeon".
**Identifications:**
Unknown, Bart J. Bok, Unknown, Arthur Sayer, Cecilia Payne, Henrietta Swope, Mildred Shapley, Helen Sawyer, Sylvia Mussels, Adelaide Ames.
**Use/Copyright:** Copyright held by Charles Reynes, used here with permission
|
| | [[link]](#PinaforeWorking)**1929/12/31**
A scene from Observatory Pinfore, with Astronomers and Computers hard at work. Based on the people (and the books), this may be somewhere in the first scene of the play. If so, this could be the Winslow Upton character standing, as the right set of people are on stage for Upton's reciting of "I know the value of a kindly chorus..."
The portrait of Galileo hanging on the right still [hangs in the Observatory today;](http://hea-www.harvard.edu/~fine/Observatory/_related_GalileoSustermansCarlton.html) it is the copy by Carlton gifted in 1890.
**Identifications**
**Use/Copyright:** Copyright held by Charles Reynes, used here with permission
|
| | [[link]](#ComputersWithoutPickering)**Earliest source:** "A group of women computers [photographic group portrait, ca. 1900]." *Harvard University Archives / HUPSF Observatory (45).* Harvard Libraries, [olvwork360664](references.html#olvwork360664)
A group of women computers [photographic group portrait, ca. 1900]
ca. 1900
|
| | [[link]](#FlemingDiamond)**Earliest source:** "[Williamina P. Fleming, photographic portrait, ca. 1890]*Alternate Title:* [Fleming, Williamina P., [photographic portrait, ca. 1900]." *Harvard University Archives / HUP Fleming, Williamina (1).* Harvard Libraries, [olvwork289681](references.html#olvwork289681)
[Williamina P. Fleming, photographic portrait, ca. 1890]*Alternate Title:* [Fleming, Williamina P., [photographic portrait, ca. 1900]
ca. 1890
*Historical:* Williamina Fleming worked at the Harvard College Observatory. She analyized stellar photographs and computed data.
|
| | [[link]](#WilliaminaFlemingPhoto) |
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At 2020/02/03 22:22**[Pamela Gill Byrne](/~fine/cgi/showit.cgi?method=r&email=4%2B%25u%22v.'%23yTw$%22wu()B%23y))** wrote:
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Hello! Edith and Mabel Gill were my great aunts. I can identify them for you in these (and other) photos. Would love to be able to see these in person. Is there someplace where these are on display? Thank you so much!
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<a href="ironclad.htm">
<b>Land Ironclad</b>
<br /><img src="../graphics/models/thumbs/ironclad_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
H.G. Wells's fictional vehicle from 1903 anticipated the invention of the tank. Scale 1:110 (about 10 inches / 25cm long).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="rvt.htm">
<b>RVT Re-usable Rocket</b>
<br /><img src="../graphics/models/thumbs/rvt_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
This Japanese test vehicle is used to research future spacecraft technologies. Scale 1:32 (over 4 inches / 10cm high).
<br />Skill level 2/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="ss1.htm">
<b>Scaled Composites SpaceShipOne</b>
<br /><img src="../graphics/models/thumbs/ss1_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
Burt Rutan's futuristic X-Prize contender. Now available in two versions! Scale 1:48 (about 7 inches / 18cm long).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="r101.htm">
<b>R.101</b>
<br /><img src="../graphics/models/thumbs/r101_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
The tragic British passenger airship. Scale 1:700 (13 inches / 33cm long).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="mailbox.htm">
<b>Canada Post Letter Box</b>
<br /><img src="../graphics/models/thumbs/mailbox_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
A simple, colourful model of a street letter box. Scale 1:16 (about 3.2 inches / 8cm high).
<br />Skill level 1/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="shed.htm">
<b>Cardington Airship Shed</b>
<br /><img src="../graphics/models/thumbs/shed_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
For British passenger airships. Scale 1:700 (about 15 inches / 38cm long).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="concorde.htm">
<b>Concorde</b>
<br /><img src="../graphics/models/thumbs/concorde_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
The fastest and most beautiful passenger aircraft ever built.<br />Available in Air France, British Airways, Pepsi, FedEx and Air Canada liveries. Scale 1:144 (about 17 inches / 43cm long).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="illinois.htm">
<b>The Mile-High <i>Illinois</i></b>
<br /><img src="../graphics/models/thumbs/illinois_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
Frank Lloyd Wright's bold skyscraper design. Scale 1:1700 (about 40 inches / 1m high).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="giant.htm">
<b>The <i>Giant</i></b>
<br /><img src="../graphics/models/thumbs/giant_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
Imperial Russian airship from World War I. Scale 1:350 (about 13 inches / 33cm long).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="titanic.htm">
<b>s.s. <i>Titanic</i></b>
<br /><img src="../graphics/models/thumbs/titanic_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
The legendary ocean liner. Scale 1:1200 (about 9 inches / 23cm long).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="olympic.htm">
<b>s.s. <i>Olympic</i></b>
<br /><img src="../graphics/models/thumbs/oly1918_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
"Old Reliable", the <i>Titanic's</i> lucky sister ship.<br />Available in civilian and wartime liveries. Scale 1:1200 (about 9 inches / 23cm long).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="britannic.htm">
<b>s.s. <i>Britannic</i></b>
<br /><img src="../graphics/models/thumbs/britannic_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
The <i>Titanic's</i> tragic younger sister.<br />Available in civilian and hospital ship liveries. Scale 1:1200 (about 9 inches / 23cm long).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="grafzep.htm">
<b>LZ.127 <i>Graf Zeppelin</i></b>
<br /><img src="../graphics/models/thumbs/grafzep_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
The famous German airship. Scale 1:700 or 1:96 (over 13 ins/33cm or 23 ins/58cm long).
<br />Skill level 3/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="krop_airfield_bldgs.htm">
<b>World War II Airfield Buildings</b>
<br /><img src="../graphics/models/thumbs/control_tower1_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
From German designer Alexander Krop. Scale 1:144 .
<br />Skill level 2/5
</div>
</div>
</div>
</li> <li><div class="w3-dropdown-hover w3-white clickable-div">
<a href="eurotunnel_loco.htm">
<b>Eurotunnel Shuttle Locomotive</b>
<br /><img src="../graphics/models/thumbs/loco_t.jpg" alt="" /><span class="link-spanner"></span>
</a>
<div class="w3-dropdown-content w3-bar-block w3-border shift_up">
<div class="w3-container">
The locomotive for the Channel Tunnel Shuttle train. Scale 1:160 (N gauge) (about 5.5 inches / 14cm long).
<br />Skill level 2/5
</div>
</div>
</div>
</li> </ul>
</div>
<div class="w3-black w3-center w3-padding-16">Last updated on <b>5 February 2021</b>
<br />Copyright 1999-2021 by Ralph Currell.
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Free Card Models - Currell.net
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### [Return to Home Page](../index.htm)
[Introduction](./index.htm)
[Free Models](./mod_free.htm)
[Photo Gallery](./mod_gallery.htm)
[Links](./mod_links.htm)
[Contact Me](./mod_contact.htm)
[![Return to Home Page](../graphics/currell_blu_med.gif "Return to Home Page")](../index.htm)
[Models Introduction](./index.htm "Models Intro page")
[Photo Gallery](./mod_gallery.htm "Photo Gallery page")
[Links](./mod_links.htm "Links page")
[Contact Me](./mod_contact.htm "Contact form")
### Free Models
These card models may be downloaded for your personal enjoyment.
*Note to web site owners! If you want to offer these models on your site, please read [this](./link_me.htm) first.*
The kits vary in complexity, and many are not suitable for beginning card modelers. I've assigned a skill level to each kit to help you judge whether the kit is within your ability.
To Print Your Model
You will need a printer capable of printing on card stock. In addition, you'll need a PDF reader such as Adobe's Acrobat Reader or Foxit Reader to open and print the files (see the [links](./mod_links.htm) pages if you need a reader program).
Download the files. For most models there are two files: the instructions and the parts layout (simpler models may have parts and instructions combined in a single document).
Open and print the model files with a PDF reader program. The instructions may be printed on ordinary printer paper. The parts layout should be printed onto card stock. The "weight" (thickness) of the stock will depend on the capabilities of your printer and your own preference. 67-pound cover stock (approx 8.5 thousandths of an inch or 0.2 mm thick) is recommended.
You will need a printer capable of printing on card stock. In addition, you'll need a PDF reader such as Adobe's Acrobat Reader or Foxit Reader to open and print the files (see the [links](./mod_links.htm) pages if you need a reader program).
Download the files. For most models there are two files: the instructions and the parts layout (simpler models may have parts and instructions combined in a single document).
Open and print the model files with a PDF reader program. The instructions may be printed on ordinary printer paper. The parts layout should be printed onto card stock. The "weight" (thickness) of the stock will depend on the capabilities of your printer and your own preference. 67-pound cover stock (approx 8.5 thousandths of an inch or 0.2 mm thick) is recommended.
#### Models by category
* [AllModels](?filter=all#filter_tabs)
* [Airplanes](?filter=airplane#filter_tabs)
* [Airships](?filter=airship#filter_tabs)
* [Spacecraft /Rockets](?filter=spacerocket#filter_tabs)
* [Buildings](?filter=building#filter_tabs)
* [LandVehicles](?filter=vehicle#filter_tabs)
* [Ships](?filter=ship#filter_tabs)
* [Fictional /Proposed](?filter=proposed_fiction#filter_tabs)
* [Other](?filter=miscellaneous#filter_tabs)
* [**V-2 Rocket**
![](../graphics/models/thumbs/v2_t.jpg)](v2.htm)
The world's first ballistic missile. Scale 1:32 (over 17 inches / 43cm high).
Skill level 3/5
* [**V-1 Flying Bomb**
![](../graphics/models/thumbs/v1_t.jpg)](v1.htm)
Predecessor of the modern cruise missile. Scale 1:32 (over 10 inches / 25cm long).
Skill level 3/5
* [**Moon Rocket *Friede***
![](../graphics/models/thumbs/friede_t.jpg)](friede.htm)
From the 1929 silent film *Woman in the Moon*. Scale 1:144 (about 12 inches / 30cm high).
Skill level 3/5
* [**N-1 Rocket Booster**
![](../graphics/models/thumbs/n1_t.jpg)](n1.htm)
The ill-fated Soviet rival to the Saturn V moon rocket. Scale 1:144 or 1:96 (about 29 ins/73cm or 44 ins/1,1m tall).
Skill level 4/5
* [**Link Trainer**
![](../graphics/models/thumbs/trainer_t.jpg)](trainer.htm)
The first realistic flight simulator. Scale 1:24 (about 5 inch / 13cm wingspan).
Skill level 4/5
* [**R.100**
![](../graphics/models/thumbs/r100_t.jpg)](r100.htm)
The famous British passenger airship. Scale 1:700 (about 12 inches / 30cm long).
Skill level 3/5
* [**Airship Mooring Mast**
![](../graphics/models/thumbs/mast_t.jpg)](mast.htm)
For British passenger airships. Scale 1:700 (about 3.5 / 9cm inches tall).
Skill level 3/5
* [**Vickers Transoceanic Airship**
![](../graphics/models/thumbs/vickers_t.jpg)](vickers.htm)
Proposed passenger airship from 1919. Scale 1:700 (about 14 inches / 36cm long).
Skill level 3/5
* [**FMX-4 Facetmobile**
![](../graphics/models/thumbs/fmx4_t.jpg)](facet.htm)
A homebuilt aircraft using the lifting body principle. Scale 1:48 (about 5 inches / 13cm long).
Skill level 2/5
* [**Land Ironclad**
![](../graphics/models/thumbs/ironclad_t.jpg)](ironclad.htm)
H.G. Wells's fictional vehicle from 1903 anticipated the invention of the tank. Scale 1:110 (about 10 inches / 25cm long).
Skill level 3/5
* [**RVT Re-usable Rocket**
![](../graphics/models/thumbs/rvt_t.jpg)](rvt.htm)
This Japanese test vehicle is used to research future spacecraft technologies. Scale 1:32 (over 4 inches / 10cm high).
Skill level 2/5
* [**Scaled Composites SpaceShipOne**
![](../graphics/models/thumbs/ss1_t.jpg)](ss1.htm)
Burt Rutan's futuristic X-Prize contender. Now available in two versions! Scale 1:48 (about 7 inches / 18cm long).
Skill level 3/5
* [**R.101**
![](../graphics/models/thumbs/r101_t.jpg)](r101.htm)
The tragic British passenger airship. Scale 1:700 (13 inches / 33cm long).
Skill level 3/5
* [**Canada Post Letter Box**
![](../graphics/models/thumbs/mailbox_t.jpg)](mailbox.htm)
A simple, colourful model of a street letter box. Scale 1:16 (about 3.2 inches / 8cm high).
Skill level 1/5
* [**Cardington Airship Shed**
![](../graphics/models/thumbs/shed_t.jpg)](shed.htm)
For British passenger airships. Scale 1:700 (about 15 inches / 38cm long).
Skill level 3/5
* [**Concorde**
![](../graphics/models/thumbs/concorde_t.jpg)](concorde.htm)
The fastest and most beautiful passenger aircraft ever built.
Available in Air France, British Airways, Pepsi, FedEx and Air Canada liveries. Scale 1:144 (about 17 inches / 43cm long).
Skill level 3/5
* [**The Mile-High *Illinois***
![](../graphics/models/thumbs/illinois_t.jpg)](illinois.htm)
Frank Lloyd Wright's bold skyscraper design. Scale 1:1700 (about 40 inches / 1m high).
Skill level 3/5
* [**The *Giant***
![](../graphics/models/thumbs/giant_t.jpg)](giant.htm)
Imperial Russian airship from World War I. Scale 1:350 (about 13 inches / 33cm long).
Skill level 3/5
* [**s.s. *Titanic***
![](../graphics/models/thumbs/titanic_t.jpg)](titanic.htm)
The legendary ocean liner. Scale 1:1200 (about 9 inches / 23cm long).
Skill level 3/5
* [**s.s. *Olympic***
![](../graphics/models/thumbs/oly1918_t.jpg)](olympic.htm)
"Old Reliable", the *Titanic's* lucky sister ship.
Available in civilian and wartime liveries. Scale 1:1200 (about 9 inches / 23cm long).
Skill level 3/5
* [**s.s. *Britannic***
![](../graphics/models/thumbs/britannic_t.jpg)](britannic.htm)
The *Titanic's* tragic younger sister.
Available in civilian and hospital ship liveries. Scale 1:1200 (about 9 inches / 23cm long).
Skill level 3/5
* [**LZ.127 *Graf Zeppelin***
![](../graphics/models/thumbs/grafzep_t.jpg)](grafzep.htm)
The famous German airship. Scale 1:700 or 1:96 (over 13 ins/33cm or 23 ins/58cm long).
Skill level 3/5
* [**World War II Airfield Buildings**
![](../graphics/models/thumbs/control_tower1_t.jpg)](krop_airfield_bldgs.htm)
From German designer Alexander Krop. Scale 1:144 .
Skill level 2/5
* [**Eurotunnel Shuttle Locomotive**
![](../graphics/models/thumbs/loco_t.jpg)](eurotunnel_loco.htm)
The locomotive for the Channel Tunnel Shuttle train. Scale 1:160 (N gauge) (about 5.5 inches / 14cm long).
Skill level 2/5
Last updated on **5 February 2021**
Copyright 1999-2021 by Ralph Currell.
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| https://currell.net/models/mod_free.htm |
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| http://www.noveltyansweringmachine.com/ |
<html>
<head>
<meta http-equiv="Content-Type" content="text/html; charset=windows-1252">
<meta name="GENERATOR" content="Microsoft FrontPage 5.0">
<meta name="ProgId" content="FrontPage.Editor.Document">
<meta name="keywords"
content="Pyramids, pyramids, Egypt, Egyptian pyramids, pyramid, Great Pyramid, pyramids of Giza, Giza Plateau, Cheops, Khufu, Khafre, Chepren, Mycerinus, Menkaura, Abu Sir, Abu Roash, Meidum, Meydum, Saqqara, Dahshur, Abu Ghurab, 4th Dynasty, Old Kingdom">
<title>The Great Pyramid of Khufu - Guardian's Egypt - Guardian's Ancient
Egyptian Pyramid Primer</title>
</head>
<body>
<div align="center">
<center>
<table border="0" cellpadding="0" cellspacing="0" style="border-collapse: collapse" bordercolor="#111111" width="85%" id="AutoNumber1">
<tr>
<td width="100%">
<div align="center">
<center>
<table border="0" width="100%" height="1">
<tr>
<td width="63%" colspan="2" height="1">
<p class="MsoHeading7" align="left" style="text-align:left"><a href="http://guardians.net/egypt" target="_top">
<img src="http://www.guardians.net/images/guard.gif"
alt="Guardian's Egypt" border="0" width="455" height="60"></a>
</td>
<td width="37%" valign="top" rowspan="2" height="1"><b><font size="4"><i>
CONTENTS:</i></font></b>
<ul>
<li><a href="#plan"><b>Plan</b></a></li>
<li><a href="#new"><b>New Features</b></a></li>
<li><a href="#p&c"><b>The Passageways and Chambers</b></a></li>
<li><a href="#subterranean"><b>The Subterranean Chamber</b></a></li>
<li><a href="#ascending"><b>The Ascending Passageway</b></a></li>
<li><a href="#middle"><b>The Middle Chamber</b></a></li>
<li><a href="#antechamber"><b>The Antechamber</b></a></li>
<li><a href="#main"><b>The Main Chamber</b></a></li>
<li><a href="#relieving"><b>Relieving Chambers</b></a></li>
<li><a href="#wellshaft"><b>The Well Shaft</b></a></li>
<li><b><a href="#complex">Khufu Pyramid Complex</a></b></li>
<li><b><a href="#satellite">Khufu Satellite Pyramids</a></b></li>
<li><a href="#bibliography"><b>Bibliography</b></a></li>
<li><b><a href="http://guardians.net/egypt/" target="_top">Back to
Guardian's Egypt</a></b></li>
</ul>
</td>
</tr>
<tr>
<td width="39%" height="26">
<span style="mso-bidi-font-size:10.0pt"><b><font size="5">The Great Pyramid of Khufu</font></b></span><br>
<i><b>Khufu Belongs to the Horizon</b><br>
</i><b>Original Height: 146.6 m (480.96 ft)<br>
Current Height: 138.75 m (455.21 ft)<br>
Length of Side: 230.37 (755.8 ft)<br>
Angle: 51º 50
40<br>
Estimated Volume: 2,521,000 cu m
</b></td>
<td width="25%" height="26">
<p align="center"><a href="../khufu.htm" target="_top">
<img alt="Statue of Khufu - now at the Egyptian Museum in Cairo" hspace="5" src="../GP/images/khufust1.gif" vspace="5" border="0" width="111" height="219"></a></td>
</tr>
</table>
</center>
</div>
<span style="mso-ignore:vglayout">
<table cellpadding="0" cellspacing="0">
<tr>
<td><a name="plan">
<img src="GreatPyramid/images/GreatP1.gif" v:shapes="_x0000_s1032" width="624" height="349"></a></td>
</tr>
</table>
</span>
<p class="MsoHeading7" align="left" style="text-align:left"><span style="font-weight:
normal">Considered to represent the pinnacle of the Pyramid Age, the Great
Pyramid is the epitome of the knowledge and experience of all previous pyramids.
Khufu had every advantage in growing up in an atmosphere of the several pyramid
building projects of his father Sneferu. In light of this it becomes easier to
understand that Khufu was more than qualified to oversee and organize the grand
task of building the monument that is the only surviving member of the Seven
Wonders of the World. So much uninformed speculation abounds as to the origin,
engineering and construction of the Great Pyramid, though we have a wealth of
archaeological evidence to piece together much of the accomplishment. Recently,
remnants of ramps have been found by Dr. Zahi Hawass on the south side of the
pyramid that attest that some type of ramping was indeed used in the
construction of this monument. The attribution of the pyramid to King Khufu is
supported by workmans markings that were found in the pyramid in small
chambers that were never intended to be opened. <o:p>
</o:p>
</span></p>
<p class="MsoNormal" style="text-align:justify">The precision with which the
pyramid was executed is often the source of marvel and speculation. It is likely
that the attention to this precision was related to the many structural problems
encountered in previous pyramids. To minimize many of the previous errors, the
attention to precision produced a pyramid whose base is level within 2.1 cm
(less than 1 inch!), with the only difference in the length of the sides being
4.4 cm (1.75 in). The base covers an area of 13 ½ acres. The blocks used in the
pyramid are large, with a commonly stated average of 2.5 tons. Many blocks are
indeed smaller than this, the blocks toward the top decrease in size. Some of
the casing stones at the base are very large, weighing as much as 15 tons. The
heaviest blocks are the granite blocks used to roof the kings chambers and the
weight relieving chambers above the kings chamber. These are estimated to
weigh from 50 to 80 tons each!!<o:p>
</o:p>
</p>
<h4>
<font size="4"><b>
<img src="GreatPyramid/images/GreatP2.gif" align="left" hspace="12" v:shapes="_x0000_s1028" width="176" height="498"></b></font><span style="mso-bidi-font-size:
10.0pt"><font size="4"><b><a name="new"></a>New Features Since Previous Pyramids</b></font></o:p>
</span></h4>
<p class="MsoNormal">The Great Pyramid has an internal arrangement that is more
elaborate than most of the other pyramids. Here, for the first time<span style="mso-spacerun: yes">
</span>we see a series of upper passageway and chambers that exist within the
body of the pyramid. A unique ascending passageway leads to a magnificent
corbelled gallery, know as the Grand Gallery. While it is tempting for people to
think that this gallery looks to be ceremonial in appearance, the function of
the gallery is more likely a holding place for large blocks which were to seal
off the upper chambers after the burial of the king, in order to secure his
sacred burial.<br>
<br>
<span style="mso-bidi-font-size:13.5pt">The main burial chamber has two small
shafts in the north </span><span style="mso-bidi-font-size:
13.5pt">and south walls which extend through the substance of the pyramid to the
surface. The northern channel is only 5" high x 7" wide and ascends at
an angle of approximately 31</span><span style="mso-char-type: symbol; mso-symbol-font-family: Symbol; font-family: Symbol; mso-ascii-font-family: Times New Roman; mso-hansi-font-family: Times New Roman">°</span><span style="mso-bidi-font-size:
13.5pt">and is 235' in length. The southern channel measures about 8" high
x 12" wide, rises at an angle of 45</span><span style="mso-char-type: symbol; mso-symbol-font-family: Symbol; font-family: Symbol; mso-ascii-font-family: Times New Roman; mso-hansi-font-family: Times New Roman">°</span><span style="mso-bidi-font-size:
13.5pt"> and is 175' in length. The middle chamber, the so-called Queen's
chamber, has an even more peculiar feature. It also has similar small shafts,
though these end with a closing plug and do not appear to pierce through to the
outer surface of the pyramid.</span></p>
<p class="MsoNormal"> </p>
<p class="MsoNormal"> </p>
<p class="MsoHeading7" style="page-break-after:auto"><span style="font-size:14.0pt;
mso-bidi-font-size:10.0pt"><br>
<a name="p&c"></a>
<b>The Passageways and Chambers</b><o:p>
</o:p>
</span></p>
<p class="MsoNormal">
<img src="GreatPyramid/images/GreatP3.jpg" align="right" hspace="12" v:shapes="_x0000_s1029" width="393" height="350">The
pyramid has three main chambers. The original entrance of the pyramid is located
7.29 m (24 ft) east of the center of the pyramid on the north face, at a height
of 16.76 m (55 ft) above ground level.<br>
</p>
<p class="MsoNormal">
<b><span style="font-size:14.0pt;mso-bidi-font-size:10.0pt"><a name="subterranean"></a>The Subterranean
Chamber</span></b><br>
This leads to a descending passageway which is about 345 ft in length and slopes
downward at an angle of 26<span style="mso-char-type: symbol; mso-symbol-font-family: Symbol; font-family: Symbol; mso-ascii-font-family: Times New Roman; mso-hansi-font-family: Times New Roman">°</span>3123
first through the superstructure of the pyramid and then down through the
bedrock. The end of this passage levels off for 29 feet, has an unfinished
niche, and then leads to a subterranean chamber. This curious chamber is only
roughly hewn out of the bedrock and looks almost as though it is a quarry. In
the south wall, opposite the entrance, is a blind passageway that runs for a
distance of<span style="mso-spacerun: yes"> </span>16.15m (53 ft). It is
possible that this passageway was originally intended to lead to a second
subterranean chamber,<span style="mso-spacerun:
yes"> </span>the idea of which for some reason was abandoned. Along the
east wall, halfway between the north and south walls, is a square cut shaft that
has a depth of 15 ft. The bottom of this shaft is filled with rubble and debris
and one account mentions that when cleared the shaft has a depth of almost 60
ft!<br>
</p>
<div align="center">
<center>
<table border="0" width="100%">
<tr>
<td width="50%" valign="top">
<p class="MsoNormal">
<b><span style="font-size:14.0pt;
mso-bidi-font-size:10.0pt"><a name="ascending"></a>The Ascending Passageway</span></b></p>
<p class="MsoNormal" style="text-align:justify"> At a distance of
approximately 60 ft from the entrance there is a hole through the masonry roof
of the descending passageway which leads to the first ascending passageway seen
in a major pyramid. This passage is 129 feet in length and rises at a gradient
of 26<span style="mso-char-type: symbol; mso-symbol-font-family: Symbol; font-family: Symbol; mso-ascii-font-family: Times New Roman; mso-hansi-font-family: Times New Roman">°</span>230.
Its lower end was plugged with three 7-ton granite slabs, which are still in
place. Currently, one enters the ascending passageway through a hole that was
hewn around these slabs from an intrusive entrance. The ascending passageway
leads to the Grand Gallery. One unique and ingenious feature of this passage is
that it is supported by a series of four single stones which were hollowed out.
Through these the corridor was laid, these have become known as the girdle
stones. There are also 3 half girdles which are actually two stones
combined for the same purpose. At the point where the Grand gallery is first
entered there is a level landing which leads straight to the middle chamber.</p>
<p> </td>
<td width="50%">
<img src="GreatPyramid/images/GreatP4.jpg" v:shapes="_x0000_s1031" vspace="1" border="0" width="328" height="358"></td>
</tr>
</table>
</center>
</div>
<div align="center">
<center>
<table border="0" width="100%">
<tr>
<td width="50%"> <b><span style="font-size:14.0pt;
mso-bidi-font-size:10.0pt"><a name="middle"></a>The Middle Chamber<br>
</span></b>
<img src="GreatPyramid/images/GreatP5.jpg" align="left" hspace="12" v:shapes="_x0000_s1030" width="433" height="333"></td>
<td width="50%" valign="top"><span style="font-weight:normal">The
passageway that leads from the Grand Gallery to the middle chamber is 45.72 m
(150 ft) in length. This chamber is called the Queens Chamber in modern
time, though this is truly a misnomer. The chamber is located at the 25<sup>th</sup>
course of masonry. The chamber is made of limestone and has a pointed roof and a
niche in its east wall that probably originally housed a statue of the king. It
is sometimes suggested that this room served as serdab. It has been assumed by
some that this chamber was never finished,
</span></td>
</tr>
</table>
</center>
</div>
<p class="MsoNormal" align="center">
<img alt="QC-roof-plan" src="GreatPyramid/images/GP-QC-ns.jpg" width="550" height="359"> </p>
<p class="MsoNormal" style="text-align:justify"><span style="font-weight: normal">t</span><span style="font-weight:normal">he evidence proposed to support this
theory include the fact that the floor appears to be only roughly finished.
Also, there are small rectangular apertures, in the north and south walls which
lead to small shafts which appear to have been prematurely discontinued. Similar
shafts in the upper chamber pierce through the surface of the pyramid. The
southern shaft<span style="mso-spacerun: yes"> </span>of this chamber has
been determined by robotic exploration to abruptly end with a plugging block.
The northern shaft has yet to be explored, but no exit aperture has been found
outside the pyramid. <o:p>
</o:p>
</span></p>
<p class="MsoNormal" style="text-align:justify">
<b>
<img src="GreatPyramid/images/GreatP6.jpg" align="right" hspace="12" v:shapes="_x0000_s1027" width="258" height="240"></b><span style="font-size:14.0pt;mso-bidi-font-size:10.0pt"><b><a name="antechamber"></a>The
Antechamber </b><o:p>
</o:p>
</span></p>
<p class="MsoNormal" style="text-align:justify"> At the south end of the
Grand Gallery there is an entrance that leads to an antechamber between the
grand gallery and the main chamber. It has a configuration that housed large
portcullis blocking slabs which were designed to be lowered to seal the chamber
after the burial of the king.</p>
<p class="MsoHeading7" align="left" style="text-align:left;page-break-after:auto"><span style="font-size:14.0pt;mso-bidi-font-size:10.0pt"><b><a name="main"></a>The
Main Chamber</b></span><br>
<br>
<span style="font-weight:normal">The main chamber, known as the Kings
Chamber, is a remarkable chamber built entirely of rose granite. It is situated
at the 50<sup>th</sup> course of masonry. The stones used to construct this
chamber are the heaviest known stones in the entire pyramid. There are 21 stones
comprising the floor alone. The walls are comprised of 101 stones and there are
9 huge beams forming the ceiling. This chamber contains the granite sarcophagus
and also has small apertures leading to shafts on the north and south walls.
Unlike similar shafts in the Queens Chamber, these pierce through the outer
surface of the pyramids. Presently there is a ventilation fan fitted into the
southern shaft and this regulates the moisture in the chamber, minimizing the
damage caused by the moisture produced by the breath and sweat of visitors. As
with all other exposed surfaces in this pyramid, there are no inscriptions or
carved reliefs on the chamber walls.<o:p>
</o:p>
</span></p>
<p class="MsoHeading7" style="page-break-after:auto">
<img src="GreatPyramid/images/GreatP7.jpg" align="left" hspace="12" v:shapes="_x0000_s1033" width="315" height="266"><span style="font-weight:normal"><o:p>
</o:p>
</span></p>
<p class="MsoHeading7" align="left" style="text-align:left;page-break-after:auto"><span style="font-weight:normal">The
coffer is no longer has its lid and the southeast upper corner has been
broken away. It is also made from a single block of rose granite weighing about
3.75 tons. Its western edge sports three drilled pinion holes that were used to
hold the lid in place after the interment. The lid would have weighed over 2
tons and was slid into place within angled grooves. The size of the coffer
necessitates that the chamber was built with the coffin already in place it
would not have fit through the entrance, nor would it have fit through the lower
section of the ascending passageway.<span style="mso-spacerun: yes"> </span><br>
<br>
</span><br>
</p>
<p class="MsoHeading7" align="left" style="text-align:left;page-break-after:auto"><span style="font-size:14.0pt;mso-bidi-font-size:10.0pt"><b><a name="relieving"></a>The
Relieving Chambers</b></span><br>
<span style="font-weight:normal">When blocks were cut at the various quarries
they were organized and cataloged in order to prepare them for transportation to
the site and final placement during assembly. The blocks were marked in red ink
to fulfill this purpose and these markings would include the placements
information and often also the name of the work-gang that would be directly
working with the blocks. When the blocks were placed the markings were rubbed
off of any surface that would be showing. Fortunately, they often did NOT remove
these markings on surfaces which were not intended to be exposed. This has left
us with some examples of these markings which can be seen on many sites. We will
see many examples of these types of markings. <o:p>
</o:p>
</span></p>
<p class="MsoHeading7" style="page-break-after:auto"><span style="font-weight:
normal"> </span><span style="mso-ignore:vglayout;position:
relative;z-index:7;left:-31px;top:0px;width:700px;height:529px"><img width="700" height="529" src="GreatPyramid/images/GreatP8.jpg" v:shapes="_x0000_s1026"></span>
<br style="mso-ignore:vglayout" clear="ALL">
<span style="font-weight:normal">In the Great Pyramid, chambers were discovered
by blasting with dynamite that are located above the main burial chamber. These
are commonly referred to as relieving chambers as they appear to have been
included to relieve the weight of the blocks above the main chamber to preserve
that chamber from collapse. Evidence that these chambers were never meant to be
entered can be seen by the presence of workmans markings in red ink. As an
added bonus, the markings in these small chambers<span style="mso-spacerun:
yes"> </span>provide us with both the name of the work-gang responsible
for those blocks, but also with the name of the king that built the pyramid,
King Khufu. This is the most compelling evidence of the ownership of the pyramid
that we see in any pyramid until the Pyramid of Unas in the 5<sup>th</sup>
Dynasty.</span></p>
<p class="MsoHeading7" style="page-break-after:auto"><span style="font-size:14.0pt;mso-bidi-font-size:10.0pt"><b><a name="wellshaft"></a>The
Well Shaft</b></span><span style="font-weight:normal"><o:p>
</o:p>
</span></p>
<p class="MsoHeading7" align="left" style="text-align:left;page-break-after:auto">
<img src="GreatPyramid/images/GreatP9.jpg" align="left" hspace="12" v:shapes="_x0000_s1034" width="362" height="253"><span style="font-weight:normal"><span style="mso-spacerun: yes"> </span>Another
unusual feature if the Great Pyramid is the Well Shaft and grotto.<o:p>
</o:p>
</span></p>
<p class="MsoHeading7" align="left" style="text-align:left;page-break-after:auto"><span style="font-weight:normal">This
well shaft is a roughly cut passage that connects the lower portion of the Grand
Gallery with the lower portion of the descending passageway. It is about 28
square throughout its course and in places there are rough footholes. It is
believed that this obscure passageway was cut to act as an escape route for the
workers that would slide the large portcullis blocks into place sealing the
burial. Portcullis blocks were lowered into place in the antechamber sealing off
the main burial chamber and then three other 7-ton granite plug stones were slid
into the ascending passageway sealing off the entire array of upper chambers.
The workers responsible for the plugging would be trapped in the Grand Gallery
and so it is theorized that the well shaft was cut to allow for their escape. In
hearing of this passage one may think that it defeats the entire purpose of the
plugging blocks, but this passage is tortuous and extremely dangerous to climb
through. The Grotto is a small cavity located where the pyramid masonry meets
the core, though this is<span style="mso-spacerun: yes"> </span>25 feet
higher than the pyramids base as this is an area in the bedrock where there was
an outcropping rise in the central pyramid plateau that was used to full
advantage in the pyramid core, alleviating the need for filling material in this
section. It is thought that the Grotto may have originally been a small natural
cavity in the bedrock that was enlarged during the tunneling of the well shaft.
Mysteriously, there is a large granite block in the grotto, and it is unclear as
to how this stone got here or why it was left here. The most likely explanation,
as evidenced by its mere dimensions, is that this granite block is one of the
portcullis stones that originally blocked the antechamber. <o:p>
</o:p>
</span></p>
<p class="MsoHeading7" style="page-break-after:auto"><span style="font-weight:
normal"> </span><span style="font-weight:normal">After the escape of the
workers, the opening at the bottom of the well shaft was probably sealed with a
block of limestone that was designed to completely camouflage the passageway.</span><br style="mso-special-character:
line-break">
</p>
<p class="MsoHeading7" align="left" style="text-align:left;page-break-after:auto"><b><span style="font-size:14.0pt;mso-bidi-font-size:10.0pt"><a name="complex"></a></span><span style="mso-bidi-font-size: 10.0pt"><font size="5">The
Khufu Pyramid Complex</font></span><br>
<font size="4"><span style="mso-bidi-font-size: 10.0pt"><a name="mortuary">T</a>he
Mortuary Temple</span></font></b></p>
<div align="center">
<center>
<table border="0" width="100%">
<tr>
<td width="100%">
<p align="center"><span style="mso-ignore:vglayout">
<img src="GreatPyramid/images/GreatP3.gif" v:shapes="_x0000_s1027" align="center" border="0" width="500" height="338"></span></td>
</tr>
</table>
</center>
</div>
<p><span style="font-weight:normal">All that remains of the Mortuary temple of
Khufu are the remnants of the floor which was paved with black basalt. The floor
plan is much larger than the chapels associated with the Pyramid at Meidum and
the Bent Pyramid. The temple is very different from Mortuary temples that
preceded it or followed it. Sockets are evident in the floor which would have
held the granite pillars that comprised the colonnade that surrounded an open
court. At the western end of the temple is a recess thought to be a sanctuary
and signs of an outer wall. This is flanked by two vestibules. The interior
walls were made of limestone and were carved with fine reliefs. There are no
sign that there were any niches in this temple. This temple is the first known
temple to make use of limestone, granite and basalt.<span style="mso-spacerun: yes">
</span><o:p>
</o:p>
</span></p>
<p class="MsoHeading7" align="left" style="text-align:left;page-break-after:auto"><br>
<b><font size="4">The Valley Temple of Khufu</font></b></p>
<p align="left" style="text-align:left;page-break-after:auto"><span style="font-weight:normal">The
Valley Temple of Khufu has not yet been found though it is assumed that it
existed and lies at the end of the causeway. Presently, this leads to under the
present day village of Nazlet el-Saman, and has yet to be uncovered and
explored.<br>
<br>
</span><b><span style="mso-bidi-font-size: 10.0pt"><font size="4">The Boat Pits</font></span></b></p>
<p align="left" style="text-align:left;page-break-after:auto"><span style="font-weight:normal">Five
boats pits have been discovered in the immediate area around Khufus pyramid.
Two are on the southern side of the main pyramid, two are on its eastern side
flanking the Mortuary temple and the last is to the north of the causeway. In
the southeastern pit the first intact boat was found dismantled in the pit. This
was reassembled and now resides in a special climate controlled museum on the
south side of the main pyramid. The southwestern pit has been found to contain
yet another boat which still remains in situ.<br>
<br>
</span>
<b><font size="4"><a name="satellite"></a>The Satellite Pyramids of Khufu</font></b></p>
<div align="center">
<center>
<table border="0" width="100%">
<tr>
<td width="50%"><span style="mso-ignore:vglayout">
<img src="GreatPyramid/images/GreatP2.jpg" v:shapes="_x0000_s1026" align="left" border="0" width="431" height="677"></span></td>
<td width="50%" valign="top"><span style="font-weight:normal">The Great
Pyramid has three smaller so-called satellite pyramids on its north
side. These are often referred to as the Queens Pyramids, referring
to three queens that were associated with these pyramids. The
northern-most pyramid is known as the Pyramid of</span> <span style="font-weight:normal">Hetepheres
(known to Egyptologists as GI-a), the next the Pyramid of Meritetes
(GI-b), and the southern is known as the Pyramid of Henutsen (GI-c)<o:p>
</o:p>
</span>
<p style="page-break-after:auto"><span style="font-size:12.0pt;mso-bidi-font-size:10.0pt;font-weight:normal;
text-decoration:none;text-underline:none">Each of these smaller pyramids consist
of<span style="mso-spacerun: yes"> </span>a sloping descending
passageway that leads from the opening to a main chamber after taking a
short right angle turn. These chambers are subterranean and their
interiors are carved into the bedrock of the plateau. The exteriors are
badly damaged with pyramid GI-c being the most intact. There is evidence
that all three pyramids had an adjoining chapel, similar to the Mortuary
temple on the larger pyramids.<o:p>
</o:p>
</span></p>
<p style="page-break-after:auto" align="left"><span style="font-size:12.0pt;mso-bidi-font-size:10.0pt;font-family:"Times New Roman";
mso-fareast-font-family:"Times New Roman";mso-ansi-language:EN-US;mso-fareast-language:
EN-US;mso-bidi-language:AR-SA">The northernmost pyramid (GI-a) was probably
originally intended to be built slightly east of its present location.
This is evidenced by the leveling of the rock at that original location
and the beginnings of a substructure. This apparently would have
interfered with a shaft cut for the reburial of Queen Heterpheres and so
the pyramid was moved slightly west.</span></p>
<p><span style="font-size:12.0pt;mso-bidi-font-size:10.0pt;font-family:"Times New Roman";
mso-fareast-font-family:"Times New Roman";mso-ansi-language:EN-US;mso-fareast-language:
EN-US;mso-bidi-language:AR-SA">Within the last few years, Dr. Zahi Hawass has
discovered the probable satellite pyramid of Khufu north of<span style="mso-spacerun: yes">
</span>the GI-c and south of the GI-b pyramid between these and the
great pyramid. The only remains of this include a T-shaped trench,
including small descending passage and chamber. The sides of the chamber
are inwardly inclined which is similar to those of the galleries under
the east side of the Djoser Step Pyramid. The possible pyramidion for
this pyramid was also found in fragments and now stands reassembled at
the site.</span></td>
</tr>
</table>
</center>
</div>
<p style="page-break-after:auto" align="center"><b><i>This
is an excerpt from the book,<br>
Guardian's Ancient Egyptian Pyramid Primer,<br>
available soon.</i></b></p>
<p class="MsoHeading7" style="page-break-after:auto" align="center"><b>Copyright
© 2000-2005 Andrew Bayuk<i><br>
All Rights Reserved</i></b></p>
<p class="MsoHeading7" style="page-break-after:auto">
<br style="mso-special-character:line-break">
<u><span style="font-size:
14.0pt;mso-bidi-font-size:10.0pt"><b>Credits for Illustrations</b><o:p></o:p>
</span></u></p>
<p style="margin:0in;margin-bottom:.0001pt"><span style="mso-bidi-font-size:
10.0pt"><font size="3">The Great Pyramid diagrams - Guide to the Pyramids of
Egypt, Alberto Siliotti<br>
</font></span><span style="mso-bidi-font-size:13.5pt"><font size="2">Copyright
© 1997 <i>All Rights Reserved</i></font>
</span><span style="mso-bidi-font-size:
10.0pt"><font size="3"><br>
<br>
The Grand Gallery in the Great Pyramid - <a href="http://www.amazon.com/exec/obidos/ASIN/0140136347/guardiansegyptia"><b>The
Pyramids of Egypt</b></a> I. E. S. Edwards<br>
<br>
Illustration of the Subterranean Chamber of the Great Pyramid - </font></span><a href="http://www.amazon.com/exec/obidos/ASIN/0899504612/guardiansegyptia"><b>The
Egyptian Pyramids</b></a><font size="3"> <span style="mso-bidi-font-size:10.0pt">-
</span>J.P. Lepre<br>
<span style="mso-bidi-font-size:10.0pt"><br>
Illustration of the girdle stones in the Ascending Passageway of the Great
Pyramid - </span></font><a href="http://www.amazon.com/exec/obidos/ASIN/0899504612/guardiansegyptia"><b>The
Egyptian Pyramids</b></a><font size="3"> <span style="mso-bidi-font-size:10.0pt">-</span>
J.P. Lepre<br style="mso-special-character:line-break">
<br style="mso-special-character:line-break">
<span style="mso-bidi-font-size:10.0pt"><o:p></o:p>
</span><span style="mso-bidi-font-size:
10.0pt">Illustration of Queens Chamber in the Great Pyramid </span>P.
Smyth</font></p>
<p style="margin:0in;margin-bottom:.0001pt;text-align:justify"><font size="3"><span style="mso-bidi-font-size:10.0pt"><br>
</span>The Antechamber of the Great Pyramid showing Portcullis blocks - <a href="http://www.amazon.com/exec/obidos/ASIN/0500050848/guardiansegyptia"><b>The
Complete Pyramids</b></a><span style="mso-bidi-font-size:10.0pt"> Mark
Lehner<o:p></o:p>
<br>
</span></font><span style="mso-bidi-font-size:13.5pt"><font size="2">Copyright
© 1997 <i>All Rights Reserved</i></font>
</span></p>
<p style="margin:0in;margin-bottom:.0001pt;text-align:justify"><span style="mso-bidi-font-size:10.0pt"><font size="3"> <o:p>
</o:p>
</font></span></p>
<p style="margin:0in;margin-bottom:.0001pt"><span style="mso-bidi-font-size:
10.0pt"><font size="3">Illustration of the rose granite coffer of Khufu - </font></span><a href="http://www.amazon.com/exec/obidos/ASIN/0899504612/guardiansegyptia"><b>The
Egyptian Pyramids</b></a><font size="3"> J.P. Lepre</font></p>
<p style="margin:0in;margin-bottom:.0001pt;text-align:justify"><font size="3"> <o:p>
</o:p>
</font></p>
<p style="margin:0in;margin-bottom:.0001pt"><span style="mso-bidi-font-size:
10.0pt"><font size="3">The Relieving Chambers </font></span><font size="3">J
& M Edgar</font></p>
<p>
<span style="mso-bidi-font-size: 10.0pt; font-family: Times New Roman; mso-fareast-font-family: Times New Roman; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA"><font size="3"><br>
Plan of the Well Shaft and Grotto of the Great Pyramid J & M Edgar</font></span>
</p>
<h4 style="page-break-after:auto"><font size="5"><a name="bibliography"></a>Bibliography
and Suggested Reading</font></h4>
<p class="MsoNormal" style="text-align:justify"> <span style="mso-bidi-font-size:13.5pt">Edwards,
I.E.S. </span><span style="mso-bidi-font-size:
10.0pt"><font size="3"><a href="http://www.amazon.com/exec/obidos/ASIN/0140136347/guardiansegyptia"><b><i>The
Pyramids of Egypt</i></b></a></font></span><span style="mso-bidi-font-size:13.5pt">.
New York and<i> </i>London, Penguin Books, 1985<o:p>
</o:p>
</span></p>
<p class="MsoNormal"><span style="mso-bidi-font-size:13.5pt"> Fakhry, A. <b><a href="http://www.amazon.com/exec/obidos/ASIN/0226234738/guardiansegyptia"><i>The
Pyramids</i></a></b>. Chicago and London, 1969<o:p>
</o:p>
</span></p>
<p class="MsoBodyText2" align="left" style="text-align:left"><span style="mso-bidi-font-size:13.5pt">Hawass,
Zahi, <b><a href="http://www.amazon.com/exec/obidos/ASIN/0911239219/guardiansegyptia">The
Pyramids of Ancient Egypt</a></b>. Pittsburgh. 1990<o:p>
</o:p>
<o:p>
</o:p>
</span></p>
<p class="MsoNormal"><span style="mso-bidi-font-size:13.5pt">Lehner, Mark. </span><font size="3"><a href="http://www.amazon.com/exec/obidos/ASIN/0500050848/guardiansegyptia"><b><i>The
Complete Pyramids</i></b></a></font><span style="mso-bidi-font-size:13.5pt">.
London. 1997<o:p></o:p>
</span></p>
<p class="MsoNormal"><span style="mso-bidi-font-size:13.5pt">Lepre, J.P.
</span><a href="http://www.amazon.com/exec/obidos/ASIN/0899504612/guardiansegyptia"><b><i>The
Egyptian Pyramids</i></b></a><span style="mso-bidi-font-size:13.5pt">.
North Carolina. 1990<o:p>
</o:p>
<o:p>
</o:p>
</span></p>
<p class="MsoNormal"><span style="mso-bidi-font-size:13.5pt">Mendelssohn, K. <i><a href="http://www.amazon.com/exec/obidos/ASIN/0030322162/guardiansegyptia"><b>Riddle
of the Pyramids</b></a></i>. New York. 1974<o:p>
</o:p>
<o:p>
</o:p>
</span></p>
<p class="MsoNormal"><span style="mso-bidi-font-size:13.5pt">Petrie, W. M. F. <b><a href="http://www.amazon.com/exec/obidos/ASIN/1854170511/guardiansegyptia"><i>The
Pyramids and Temples of Gizeh</i></a></b>. London. 1883<o:p>
</o:p>
<o:p>
</o:p>
</span></p>
<p class="MsoNormal"><span style="mso-bidi-font-size:13.5pt">Siliotti, Alberto. <i>Guide
to the Pyramids of Egypt</i>, Cairo, 1997<o:p>
</o:p>
</span><o:p>
</o:p>
</p>
<p class="MsoNormal">Andreu, Guillemette, <b><a href="http://www.amazon.com/exec/obidos/ASIN/0810965437/guardiansegyptia"><i>Egyptian
Art in the Age of the Pyramids</i></a></b>. Ithaca and London. 1997<br>
<br>
Weeks, John. <a href="http://www.amazon.com/exec/obidos/ASIN/0521072409/guardiansegyptia"><b><i>The
Pyramids</i></b></a>. Cambridge, 1971</p>
<p> </p>
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The Great Pyramid of Khufu - Guardian's Egypt - Guardian's Ancient
Egyptian Pyramid Primer
| | | | | | | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
|
| | |
| --- | --- |
| [Guardian's Egypt](http://guardians.net/egypt)
| ***CONTENTS:**** [**Plan**](#plan)
* [**New Features**](#new)
* [**The Passageways and Chambers**](#p&c)
* [**The Subterranean Chamber**](#subterranean)
* [**The Ascending Passageway**](#ascending)
* [**The Middle Chamber**](#middle)
* [**The Antechamber**](#antechamber)
* [**The Main Chamber**](#main)
* [**Relieving Chambers**](#relieving)
* [**The Well Shaft**](#wellshaft)
* **[Khufu Pyramid Complex](#complex)**
* **[Khufu Satellite Pyramids](#satellite)**
* [**Bibliography**](#bibliography)
* **[Back to
Guardian's Egypt](http://guardians.net/egypt/)**
|
| **The Great Pyramid of Khufu**
***Khufu Belongs to the Horizon*****Original Height: 146.6 m (480.96 ft)
Current Height: 138.75 m (455.21 ft)
Length of Side: 230.37 (755.8 ft)
Angle: 51º 50
40
Estimated Volume: 2,521,000 cu m** | [Statue of Khufu - now at the Egyptian Museum in Cairo](../khufu.htm) |
| |
| --- |
| |
Considered to represent the pinnacle of the Pyramid Age, the Great
Pyramid is the epitome of the knowledge and experience of all previous pyramids.
Khufu had every advantage in growing up in an atmosphere of the several pyramid
building projects of his father Sneferu. In light of this it becomes easier to
understand that Khufu was more than qualified to oversee and organize the grand
task of building the monument that is the only surviving member of the Seven
Wonders of the World. So much uninformed speculation abounds as to the origin,
engineering and construction of the Great Pyramid, though we have a wealth of
archaeological evidence to piece together much of the accomplishment. Recently,
remnants of ramps have been found by Dr. Zahi Hawass on the south side of the
pyramid that attest that some type of ramping was indeed used in the
construction of this monument. The attribution of the pyramid to King Khufu is
supported by workmans markings that were found in the pyramid in small
chambers that were never intended to be opened.
The precision with which the
pyramid was executed is often the source of marvel and speculation. It is likely
that the attention to this precision was related to the many structural problems
encountered in previous pyramids. To minimize many of the previous errors, the
attention to precision produced a pyramid whose base is level within 2.1 cm
(less than 1 inch!), with the only difference in the length of the sides being
4.4 cm (1.75 in). The base covers an area of 13 ½ acres. The blocks used in the
pyramid are large, with a commonly stated average of 2.5 tons. Many blocks are
indeed smaller than this, the blocks toward the top decrease in size. Some of
the casing stones at the base are very large, weighing as much as 15 tons. The
heaviest blocks are the granite blocks used to roof the kings chambers and the
weight relieving chambers above the kings chamber. These are estimated to
weigh from 50 to 80 tons each!!
**New Features Since Previous Pyramids**
The Great Pyramid has an internal arrangement that is more
elaborate than most of the other pyramids. Here, for the first time
we see a series of upper passageway and chambers that exist within the
body of the pyramid. A unique ascending passageway leads to a magnificent
corbelled gallery, know as the Grand Gallery. While it is tempting for people to
think that this gallery looks to be ceremonial in appearance, the function of
the gallery is more likely a holding place for large blocks which were to seal
off the upper chambers after the burial of the king, in order to secure his
sacred burial.
The main burial chamber has two small
shafts in the north and south walls which extend through the substance of the pyramid to the
surface. The northern channel is only 5" high x 7" wide and ascends at
an angle of approximately 31°and is 235' in length. The southern channel measures about 8" high
x 12" wide, rises at an angle of 45° and is 175' in length. The middle chamber, the so-called Queen's
chamber, has an even more peculiar feature. It also has similar small shafts,
though these end with a closing plug and do not appear to pierce through to the
outer surface of the pyramid.
**The Passageways and Chambers**
The
pyramid has three main chambers. The original entrance of the pyramid is located
7.29 m (24 ft) east of the center of the pyramid on the north face, at a height
of 16.76 m (55 ft) above ground level.
**The Subterranean
Chamber**
This leads to a descending passageway which is about 345 ft in length and slopes
downward at an angle of 26°3123
first through the superstructure of the pyramid and then down through the
bedrock. The end of this passage levels off for 29 feet, has an unfinished
niche, and then leads to a subterranean chamber. This curious chamber is only
roughly hewn out of the bedrock and looks almost as though it is a quarry. In
the south wall, opposite the entrance, is a blind passageway that runs for a
distance of 16.15m (53 ft). It is
possible that this passageway was originally intended to lead to a second
subterranean chamber, the idea of which for some reason was abandoned. Along the
east wall, halfway between the north and south walls, is a square cut shaft that
has a depth of 15 ft. The bottom of this shaft is filled with rubble and debris
and one account mentions that when cleared the shaft has a depth of almost 60
ft!
| | |
| --- | --- |
|
**The Ascending Passageway**
At a distance of
approximately 60 ft from the entrance there is a hole through the masonry roof
of the descending passageway which leads to the first ascending passageway seen
in a major pyramid. This passage is 129 feet in length and rises at a gradient
of 26°230.
Its lower end was plugged with three 7-ton granite slabs, which are still in
place. Currently, one enters the ascending passageway through a hole that was
hewn around these slabs from an intrusive entrance. The ascending passageway
leads to the Grand Gallery. One unique and ingenious feature of this passage is
that it is supported by a series of four single stones which were hollowed out.
Through these the corridor was laid, these have become known as the girdle
stones. There are also 3 half girdles which are actually two stones
combined for the same purpose. At the point where the Grand gallery is first
entered there is a level landing which leads straight to the middle chamber.
| |
| | |
| --- | --- |
| **The Middle Chamber**
| The
passageway that leads from the Grand Gallery to the middle chamber is 45.72 m
(150 ft) in length. This chamber is called the Queens Chamber in modern
time, though this is truly a misnomer. The chamber is located at the 25th
course of masonry. The chamber is made of limestone and has a pointed roof and a
niche in its east wall that probably originally housed a statue of the king. It
is sometimes suggested that this room served as serdab. It has been assumed by
some that this chamber was never finished,
|
QC-roof-plan
the evidence proposed to support this
theory include the fact that the floor appears to be only roughly finished.
Also, there are small rectangular apertures, in the north and south walls which
lead to small shafts which appear to have been prematurely discontinued. Similar
shafts in the upper chamber pierce through the surface of the pyramid. The
southern shaft of this chamber has
been determined by robotic exploration to abruptly end with a plugging block.
The northern shaft has yet to be explored, but no exit aperture has been found
outside the pyramid.
**The
Antechamber**
At the south end of the
Grand Gallery there is an entrance that leads to an antechamber between the
grand gallery and the main chamber. It has a configuration that housed large
portcullis blocking slabs which were designed to be lowered to seal the chamber
after the burial of the king.
**The
Main Chamber**
The main chamber, known as the Kings
Chamber, is a remarkable chamber built entirely of rose granite. It is situated
at the 50th course of masonry. The stones used to construct this
chamber are the heaviest known stones in the entire pyramid. There are 21 stones
comprising the floor alone. The walls are comprised of 101 stones and there are
9 huge beams forming the ceiling. This chamber contains the granite sarcophagus
and also has small apertures leading to shafts on the north and south walls.
Unlike similar shafts in the Queens Chamber, these pierce through the outer
surface of the pyramids. Presently there is a ventilation fan fitted into the
southern shaft and this regulates the moisture in the chamber, minimizing the
damage caused by the moisture produced by the breath and sweat of visitors. As
with all other exposed surfaces in this pyramid, there are no inscriptions or
carved reliefs on the chamber walls.
The
coffer is no longer has its lid and the southeast upper corner has been
broken away. It is also made from a single block of rose granite weighing about
3.75 tons. Its western edge sports three drilled pinion holes that were used to
hold the lid in place after the interment. The lid would have weighed over 2
tons and was slid into place within angled grooves. The size of the coffer
necessitates that the chamber was built with the coffin already in place it
would not have fit through the entrance, nor would it have fit through the lower
section of the ascending passageway.
**The
Relieving Chambers**
When blocks were cut at the various quarries
they were organized and cataloged in order to prepare them for transportation to
the site and final placement during assembly. The blocks were marked in red ink
to fulfill this purpose and these markings would include the placements
information and often also the name of the work-gang that would be directly
working with the blocks. When the blocks were placed the markings were rubbed
off of any surface that would be showing. Fortunately, they often did NOT remove
these markings on surfaces which were not intended to be exposed. This has left
us with some examples of these markings which can be seen on many sites. We will
see many examples of these types of markings.
In the Great Pyramid, chambers were discovered
by blasting with dynamite that are located above the main burial chamber. These
are commonly referred to as relieving chambers as they appear to have been
included to relieve the weight of the blocks above the main chamber to preserve
that chamber from collapse. Evidence that these chambers were never meant to be
entered can be seen by the presence of workmans markings in red ink. As an
added bonus, the markings in these small chambers provide us with both the name of the work-gang responsible
for those blocks, but also with the name of the king that built the pyramid,
King Khufu. This is the most compelling evidence of the ownership of the pyramid
that we see in any pyramid until the Pyramid of Unas in the 5th
Dynasty.
**The
Well Shaft**
Another
unusual feature if the Great Pyramid is the Well Shaft and grotto.
This
well shaft is a roughly cut passage that connects the lower portion of the Grand
Gallery with the lower portion of the descending passageway. It is about 28
square throughout its course and in places there are rough footholes. It is
believed that this obscure passageway was cut to act as an escape route for the
workers that would slide the large portcullis blocks into place sealing the
burial. Portcullis blocks were lowered into place in the antechamber sealing off
the main burial chamber and then three other 7-ton granite plug stones were slid
into the ascending passageway sealing off the entire array of upper chambers.
The workers responsible for the plugging would be trapped in the Grand Gallery
and so it is theorized that the well shaft was cut to allow for their escape. In
hearing of this passage one may think that it defeats the entire purpose of the
plugging blocks, but this passage is tortuous and extremely dangerous to climb
through. The Grotto is a small cavity located where the pyramid masonry meets
the core, though this is 25 feet
higher than the pyramids base as this is an area in the bedrock where there was
an outcropping rise in the central pyramid plateau that was used to full
advantage in the pyramid core, alleviating the need for filling material in this
section. It is thought that the Grotto may have originally been a small natural
cavity in the bedrock that was enlarged during the tunneling of the well shaft.
Mysteriously, there is a large granite block in the grotto, and it is unclear as
to how this stone got here or why it was left here. The most likely explanation,
as evidenced by its mere dimensions, is that this granite block is one of the
portcullis stones that originally blocked the antechamber.
After the escape of the
workers, the opening at the bottom of the well shaft was probably sealed with a
block of limestone that was designed to completely camouflage the passageway.
**The
Khufu Pyramid Complex
The
Mortuary Temple**
| |
| --- |
|
|
All that remains of the Mortuary temple of
Khufu are the remnants of the floor which was paved with black basalt. The floor
plan is much larger than the chapels associated with the Pyramid at Meidum and
the Bent Pyramid. The temple is very different from Mortuary temples that
preceded it or followed it. Sockets are evident in the floor which would have
held the granite pillars that comprised the colonnade that surrounded an open
court. At the western end of the temple is a recess thought to be a sanctuary
and signs of an outer wall. This is flanked by two vestibules. The interior
walls were made of limestone and were carved with fine reliefs. There are no
sign that there were any niches in this temple. This temple is the first known
temple to make use of limestone, granite and basalt.
**The Valley Temple of Khufu**
The
Valley Temple of Khufu has not yet been found though it is assumed that it
existed and lies at the end of the causeway. Presently, this leads to under the
present day village of Nazlet el-Saman, and has yet to be uncovered and
explored.
**The Boat Pits**
Five
boats pits have been discovered in the immediate area around Khufus pyramid.
Two are on the southern side of the main pyramid, two are on its eastern side
flanking the Mortuary temple and the last is to the north of the causeway. In
the southeastern pit the first intact boat was found dismantled in the pit. This
was reassembled and now resides in a special climate controlled museum on the
south side of the main pyramid. The southwestern pit has been found to contain
yet another boat which still remains in situ.
**The Satellite Pyramids of Khufu**
| | |
| --- | --- |
|
| The Great
Pyramid has three smaller so-called satellite pyramids on its north
side. These are often referred to as the Queens Pyramids, referring
to three queens that were associated with these pyramids. The
northern-most pyramid is known as the Pyramid of Hetepheres
(known to Egyptologists as GI-a), the next the Pyramid of Meritetes
(GI-b), and the southern is known as the Pyramid of Henutsen (GI-c)
Each of these smaller pyramids consist
of a sloping descending
passageway that leads from the opening to a main chamber after taking a
short right angle turn. These chambers are subterranean and their
interiors are carved into the bedrock of the plateau. The exteriors are
badly damaged with pyramid GI-c being the most intact. There is evidence
that all three pyramids had an adjoining chapel, similar to the Mortuary
temple on the larger pyramids.
The northernmost pyramid (GI-a) was probably
originally intended to be built slightly east of its present location.
This is evidenced by the leveling of the rock at that original location
and the beginnings of a substructure. This apparently would have
interfered with a shaft cut for the reburial of Queen Heterpheres and so
the pyramid was moved slightly west.
Within the last few years, Dr. Zahi Hawass has
discovered the probable satellite pyramid of Khufu north of
the GI-c and south of the GI-b pyramid between these and the
great pyramid. The only remains of this include a T-shaped trench,
including small descending passage and chamber. The sides of the chamber
are inwardly inclined which is similar to those of the galleries under
the east side of the Djoser Step Pyramid. The possible pyramidion for
this pyramid was also found in fragments and now stands reassembled at
the site. |
***This
is an excerpt from the book,
Guardian's Ancient Egyptian Pyramid Primer,
available soon.***
**Copyright
© 2000-2005 Andrew Bayuk*All Rights Reserved***
**Credits for Illustrations**
The Great Pyramid diagrams - Guide to the Pyramids of
Egypt, Alberto Siliotti
Copyright
© 1997 *All Rights Reserved*
The Grand Gallery in the Great Pyramid - [**The
Pyramids of Egypt**](http://www.amazon.com/exec/obidos/ASIN/0140136347/guardiansegyptia) I. E. S. Edwards
Illustration of the Subterranean Chamber of the Great Pyramid - [**The
Egyptian Pyramids**](http://www.amazon.com/exec/obidos/ASIN/0899504612/guardiansegyptia) -
J.P. Lepre
Illustration of the girdle stones in the Ascending Passageway of the Great
Pyramid - [**The
Egyptian Pyramids**](http://www.amazon.com/exec/obidos/ASIN/0899504612/guardiansegyptia) -
J.P. Lepre
Illustration of Queens Chamber in the Great Pyramid P.
Smyth
The Antechamber of the Great Pyramid showing Portcullis blocks - [**The
Complete Pyramids**](http://www.amazon.com/exec/obidos/ASIN/0500050848/guardiansegyptia) Mark
Lehner
Copyright
© 1997 *All Rights Reserved*
Illustration of the rose granite coffer of Khufu - [**The
Egyptian Pyramids**](http://www.amazon.com/exec/obidos/ASIN/0899504612/guardiansegyptia) J.P. Lepre
The Relieving Chambers J
& M Edgar
Plan of the Well Shaft and Grotto of the Great Pyramid J & M Edgar
Bibliography
and Suggested Reading
Edwards,
I.E.S. [***The
Pyramids of Egypt***](http://www.amazon.com/exec/obidos/ASIN/0140136347/guardiansegyptia).
New York andLondon, Penguin Books, 1985
Fakhry, A. **[*The
Pyramids*](http://www.amazon.com/exec/obidos/ASIN/0226234738/guardiansegyptia)**. Chicago and London, 1969
Hawass,
Zahi, **[The
Pyramids of Ancient Egypt](http://www.amazon.com/exec/obidos/ASIN/0911239219/guardiansegyptia)**. Pittsburgh. 1990
Lehner, Mark. [***The
Complete Pyramids***](http://www.amazon.com/exec/obidos/ASIN/0500050848/guardiansegyptia).
London. 1997
Lepre, J.P.
[***The
Egyptian Pyramids***](http://www.amazon.com/exec/obidos/ASIN/0899504612/guardiansegyptia).
North Carolina. 1990
Mendelssohn, K. *[**Riddle
of the Pyramids**](http://www.amazon.com/exec/obidos/ASIN/0030322162/guardiansegyptia)*. New York. 1974
Petrie, W. M. F. **[*The
Pyramids and Temples of Gizeh*](http://www.amazon.com/exec/obidos/ASIN/1854170511/guardiansegyptia)**. London. 1883
Siliotti, Alberto. *Guide
to the Pyramids of Egypt*, Cairo, 1997
Andreu, Guillemette, **[*Egyptian
Art in the Age of the Pyramids*](http://www.amazon.com/exec/obidos/ASIN/0810965437/guardiansegyptia)**. Ithaca and London. 1997
Weeks, John. [***The
Pyramids***](http://www.amazon.com/exec/obidos/ASIN/0521072409/guardiansegyptia). Cambridge, 1971
**Back
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<P><FONT FACE="MS Sans Serif, Helvetica, Arial" SIZE="1">Welcome to
Welcome to Pontiac Performance.NET. The website for all things Pontiac (and everything else).
Note: The basic structure of this website is over 20 years old. Although I continue to maintain it,
there are some pages which may have some broken links and missing pages due to a transition from
Windows hosting to Linux hosting. I am continuing to update it as I can, while adding old (new) content as I find time. (3/4/2022)
<br></FONT></P>
<P><FONT FACE="MS Sans Serif, Helvetica, Arial" SIZE="1">
If you have any interest whatsoever in the cars
or parts that I've collected over the years, this
is where you can find them. This is a detailed list of every car I've
owned, as well as any rare parts I've acquired. If you see anything
you're interested in, feel free to make me an
offer! :)
</FONT></P>
<P><FONT FACE="MS Sans Serif, Helvetica, Arial" SIZE="1">
Thanks,<BR>
Pontiac Performance<BR>
<a HREF="mailto:toddjasp@bellsouth.net"> E-Mail Us!</a></FONT></P>
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| | Welcome to
Welcome to Pontiac Performance.NET. The website for all things Pontiac (and everything else).
Note: The basic structure of this website is over 20 years old. Although I continue to maintain it,
there are some pages which may have some broken links and missing pages due to a transition from
Windows hosting to Linux hosting. I am continuing to update it as I can, while adding old (new) content as I find time. (3/4/2022)
If you have any interest whatsoever in the cars
or parts that I've collected over the years, this
is where you can find them. This is a detailed list of every car I've
owned, as well as any rare parts I've acquired. If you see anything
you're interested in, feel free to make me an
offer! :)
Thanks,
Pontiac Performance
[E-Mail Us!](mailto:toddjasp@bellsouth.net) |
|
This is the section where I type a bunch of stuff that attracts browers. Yeah, it's lame but it helps
you guys find stuff you need: Fiero Pontiac V6 Oldsmobile 455 Big Block Cadillac Chevrolet Porsche 944 914 924 engine rebuild rebuilding
the engine engine removal Miami Dolphins golf cart Miami Dolphins Medical Cart Volkswagen Volvo, 2002 Crown Victoria Performance
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<br><br><br>
This is the....<BR>
<H1>Studio 54</H1>
<P>
<IMG SRC="../images/studio54.gif" ALT="Studio 54 logo"><br><br>
254 West 54th Street, New York, New York
<P>
<SPAN class="bigbold">One of THE DISCOtheques...<BR>
Welcome to the Party!</span><br><br><br>
<P>
<SPAN class="header2">I'm looking for <B>Studio 54</B> stuff like:<BR>
Invitations, Memorablia, DJ Tapes & Photos<BR>
Even Invitation/Flyer scans are wanted...<BR>
HAVE YOU GOT ANY ?<BR>
Please...</span><BR>
<A HREF="mailto:discoguy@disco-disco.com"><IMG SRC="../images/email2.gif" BORDER=0><BR>
Mail ME !</A></FONT>
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<P>
In April 26, 1977 - just off Broadway, at 254 W. 54'th Street, Manhattan, New York - THE most
well-known Disco of all times opened up its doors for the very first time. The club would soon
become the "home" of the rich, the famous and the fashion pack. The club was (of course) -
<B>Studio 54</B>.<BR>
But... Even before the club and its prominent guests "moved in", this now legendary address was
already the home of one of the world's greatest Disco labels - <A HREF="../labels/westend.shtml"><B>West
End Records</B></A>.
<P>
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<A HREF="../sounds/studio54-1.ra" OnClick="openWindowSized('studio54-mix1.shtml',450,600)" onMouseOver="self.status='Old night at Studio54 - part 1';return true" onMouseOut="self.status=' ';return true"><IMG SRC="../images/dj.gif" BORDER=0></A><BR>
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<P>
The Club was located in an old theatre and TV studio. In 1927, when the building was just built
it was the home of the "San Carlo Opera Company". It was then followed by theatres like "the New
Yorker", "Casino the Paris", "Federal Music Theatre" to finally in 1943 become a TV studio of
Columbia Broadcasting Co. (CBS). CBS used the place as a soundstage for radio and television
and from this studio successful shows like the <I>Johnny Carson show</I>, <I>Beat the clock</I>
and <I>$64000 question</I> were broadcasted. The CBS people called the place <B>Studio 52</B>,
since it was their 52'nd studio (and it was not called Studio 53 as stated by many sources').<BR>
Because of the premises former use as a TV studio the name for the new club was first meant to be
just <B>the Studio</B>, but since it was used to be called Studio 52 by CBS and it was located
in W. 54'th Street someone came up with the name <B>Studio 54</B>. The choice wasn't hard - this
WAS the name!!!
<P ALIGN=CENTER>
<IMG SRC="../images/54-studio52-ticket.jpg" HEIGHT=168 WIDTH=417 ALT="CBS Studio 52 ticket">
</P ALIGN=CENTER>
<P>
<IMG ALIGN=LEFT SRC="../images/studio54-steve-ian.gif" HEIGHT=149 WIDTH=200 ALT="Steve Rubell and Ian Schrager">
Many people had been interested in turning the old theatre into a nightclub. But it wasn't
until the two (to become) owners, <B>Steve Rubell</B> and <B>Ian Schrager</B>, saw the place
something really happened. They loved the place at once and only a week after they first saw it they
had signed the lease.<BR>
Both Steve and Ian had been working in the nightclub business before they managed to hit it off big
time with "the Studio". They had also been in the restaurant business for a long time and they currently
owned a club in Queens, called the <B>Enchanted Garden</B>.<BR>
In the Enchanted Garden Steve and Ian had a very talented DJ playing, a guy who is the pioneer DJ -
<A HREF="../djs/nicky.shtml"><B>Nicky Siano</B></A>. Nicky started playing at Steve and Ian's club in
1976 and about two weeks before they opened up Studio 54 they hired Nicky as one of the new clubs
two resident DJ's. The other resident DJ was a guy called <nobr><A HREF="../djs/richie.shtml"><B>Richie Kaczor</B></A>.</nobr>
<P>
Steve and Ian also had a third partner, <B>Jack Dushey</B>, who was a professional retailer and in real estate.
He was the new club's financial backer.<br>
Ian and Steve had first met Jack in early 1976 when he held his kids Bar Mitzvah in their club - Enchanted Garden.
The guys had started talking and they told Jack they wanted to open up a club in Manhattan. Jack, as the real
estate man he was, said he was interested in being part of that.<br>
When Rubell and Schrager had found the location they approached Dushey again and he gave the guys a couple of
hundred thousand dollars and said; <I>"Take the money and I'll get 50% of the net profit."</I><br>
Demolition and construction work took about a year and by the time <nobr>Studio 54</nobr> opened, some $600'000 -
$700'000 had been spent to get the place ready to party.
<P>
For the Premier night of the Studio 54 the guys hired this girl and party promoter named
<B>Carmen D'Alessio</B> to invite the "right" people for the grand opening. Steve and Ian had met
her at their former partner <B>Maurice Brahms</B>' club <B>Infinity</B>. Carmen got the job as the new
clubs PR manager and she had also been working with Steve and Ian earlier at the Enchanted Garden.<BR>
Time went closer and closer to the opening night, some 5000 invitations were out and people were
working day and night to get the place ready in time...<BR>
Then in April 26, 1977 - THE day was there. People were still working in the club when some of the
invited people started gathering outside the club. And about half an hour late the club opened up its
doors for the first time. There weren't much people entering at this "early" hour, but within a
couple of hours the place was crowded and outside the doors it was chaos. Even people with invitations
couldn't get in!
<P ALIGN=CENTER>
<iframe width="560" height="315" src="https://www.youtube.com/embed/7_hQjZS2BbM" title="YouTube video player" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen></iframe>
</P ALIGN=CENTER>
</TD>
</TR>
<TR><TD WIDTH=490><img src="../index/trans.gif" width="490" height="1">
<P>
<IMG ALIGN=LEFT SRC="../images/studio54d1.jpg" HEIGHT=170 WIDTH=128 ALT="Studio 54 - Dance floor">
<IMG ALIGN=RIGHT SRC="../images/studio54d2.jpg" HEIGHT=141 WIDTH=170 ALT="Studio 54 - Dance floor">
The club was huge, about 100 meters long and 80 meters wide, but it still had its theatrical feel, not only
by the spectacular people who went there, but also because of the balcony and stage was still there. In the
balcony there were sitting areas with tables and beneath the balcony was the huge parquet dance floor with all
its strobe-lit columns that descended from the ceiling and its pumping music. Around the dance floor there
were silver banquettes and the mirrored diamond-shaped main bar was located under the balconies, close to the
dance floor.<br>
<IMG ALIGN=RIGHT SRC="../images/studio54-rubberroom.jpg" HEIGHT=174 WIDTH=250 ALT="Studio 54 - the Rubber Room">
At the top of the club, in the 3rd floor, overlooking both the balcony and the huge dance floor was the infamous
<B>Rubber room</B>. The room had a High-Tec bar and was designed with thick rubber on the walls to be easily washed
down with water and soap after all the sex and drugs going on up there. Some people used to refer to the Rubber room
as "Upstairs", but there were actually more secret places above the Rubber room were more private sex took place.
Those areas were the real "Upstairs" to the initiated.<br>
In the ceiling above the dance floor there were cat walks for the maintenance of the lightning. It's said that the
owners used to spend a great deal of time up there doing drugs and having sex above the heads of the hundreds of
dancing people beneath.<br>
In the basement was the room not anyone could enter - <B>the VIP room</B>.<br>
I [<SPAN CLASS="dg"><B>Discoguy</B></span>] got a chance to talk to <B>Paolo Miranda</B>, who started working
as Busboy, and later Head Busboy, in the club in July of 1978 and was there for about 2 years. Paolo, or Paul-Michael
as he was called back then, fills me in on the VIP lounge...<br>
<I>"I wouldn't really call it a VIP lounge, it was the basement. There were wire chain link fences all around with
all the supplies for special decorations behind them. There was an Elton John pinball machine down there and a few
white plastic lawn chairs. But I was down there all the time. Also there was the 2-year anniversary party down there,
full of lots of celebrities."</I>
<P ALIGN=CENTER>
<IMG SRC="../images/richiekaczor-dj.jpg" HEIGHT=167 WIDTH=250 ALT="Studio 54 DJ - Richie Kaczor">
</P ALIGN=CENTER>
<P>
Richie Kaczor was the DJ playing this opening night and the first song he played was <I>"Devil's gun"</I>
by <B>C.J. & Co.</B>. Richie was also the DJ playing in the weekends and Nicky Siano played the second
night and in the weeknights. Nicky couldn't play weekends at "the Studio" since he owned his own
popular New York club - <B>the Gallery</B> and was playing there in the weekends. It was also Nicky
who played the night of the famous <B>Bianca Jagger</B> birthday bash in May 1977, in which she rode
into the club on a white horse led by a naked body-painted guy.<BR>
What's surprising is that while a DJ like <A HREF="../tributes/larry.shtml"><B>Larry Levan</B></A> was
well-known among the crowd of the <A HREF="paradise.shtml"><B>Paradise Garage</B></A>, not many people
knew the names of the resident DJ's of Studio 54.<BR>
Paolo adds about the DJ's: <I>"Richie Kaczor was <B>THE DJ</B> during the time I worked there. He was
truly amazing. He would blend a song for a good 10 minutes. It was seamless. You would never know the
song changed. Now a days, they blend for about 10 to 30 seconds and not very good. I got really spoiled
at 54."</I><br>
Nicky worked at Studio 54 for about half a year, then he actually got fired because he preferred to spend
hours in the bathroom getting high on drugs instead of getting high on playing records in the DJ booth.
This Nicky told me himself when I got the chance to speak to him, but for the record I also wanna tell
that he stopped taking drugs many many years ago.<BR>
Nicky also had so many memories from the Studio that it would take a whole book to tell it all,
but when he played the famous Birthday bash for <B>Bianca Jagger</B> was probably his most precious
memory. That night was really a blast, he told me.<BR>
He also told me a little about the owners of Studio 54, Steve and Ian. <I>"Steve was straight when
I met him...? Ian was always the level headed business man, and he was straight, all the time...
I love them both, Steve and Ian were really good to me, and I will always consider them great
supporters and friends."</I><br>
He thinks a little more and continues; <I>"Yes, there was also this celebrity lounge at 54 that made
Sodom and Gomorra look like kindergarten!"</I> (the VIP lounge!)<BR>
<P>
<IMG ALIGN=LEFT SRC="../images/54-entrance.jpg" HEIGHT=250 WIDTH=174 ALT="People hoping to get into Studio 54">
The Studio also had it own door policy, they wanted to get a perfect mix of people which actually
meant that even celebrities was stopped at the door and didn't get in.<br>
This young guy, <B>Marc Benecke</B> ruled the door and was instructed by Steve to mix a perfect salad
every night. That way it didn't really matter if you were famous or not - you just had to fit it at this
time.<br>
The doorman Marc even became more famous to the guests of the 54 than Ian Schrager.<br>
Steve was also often in the entrance selecting people to let in and it's said that Steve once didn't like
the shirt a guy was wearing. He told the guy he wouldn't get in with that shirt on, the guy asked if he
could get in if he took it off. Steve said yes and the guy took it off and was allowed to enter the club,
bare-chested.<br>
So it was basically just a question of matching what Steve and Marc were looking for to add to their salad for
the night.<BR>
Some people tried desperately to get in and there's actually another true story about this guy who
got stuck in the air duct in his attempt to enter the club - one way or another...<br>
I asked Paolo about the 'salad' door policy and as he says; <I>"It's what made the club so popular.
Working there meant I had no worries, and it made me feel special at the time."</I><br>
Not matching the 'salad of the day' was what happened to <B>Nile Rodgers</B> and <B>Bernard Edwards</B> of
<A HREF="../tributes/chic.shtml"><B>Chic</B></A>, when the guys were contacted by <B>Grace Jones</B>
who wanted to work with them for her next album...<br>
Grace invited them as her guests to her gig down at the Studio 54. It was New Years Eve in 1977, the
guys were all dressed up and it was snowing and freezing cold... When Nile and Bernard got to the club
the doormen couldn't find their names on the guest list. Nile and Bernard explained that they "were"
Chic and that Grace was expecting them. But the doormen just wouldn't let them in...<BR>
In anger they went back home to Nile and in just 25-30 minutes they wrote a whole song they called
"Fuck off". It went like this... "aaahh Fuck off". They just know this was a hit song and they (of
course) had to change the title to be able to release it. So they changed the text and that line to
"aaahh Freak out" and their biggest hit was a fact - <I>"Le Freak"</I>. The song topped the US charts
for 6 weeks and <I>"Le Freak"</I> became Atlantic Records biggest selling single ever. It also became
the 3'rd biggest single in the music history. It's still the most sold record ever in Canada and the
single sold over 6 million copies only in the US. But after 6 million copies sold of the single, Nile
and Bernard choose to stop the single to not have it cut down the album sales. Who knows how big it
would have become if they hadn't stopped it!?
<P>
But Nile and Bernard got their revenge... About one year later to this episode at Studio 54, everything
related to the club and its name was a big industry and at this time Ian & Steve were credited as
Executive Producers of this <A HREF="../labels/casablanca.shtml"><B>Casablanca Records</B></A> double LP called
<I>A night at Studio 54</I>. The top tune and first song out of this album was no less than - <I>"Le Freak"</I>.
Ian & Steve thanked their guests like this in the album; <I>"To all our guests at Studio 54, whose energy
made this record possible... Our sincere Thanks!"</I><BR>
Beside the great Chic track the album included other great Disco songs regularly played in the club like;
<I>"I Love the Nightlife (Disco round)"</I> (<B>Alicia Bridges</B>), <I>"Let's All Chant"</I> (<B>Michael
Zager Band</B>), <I>"Y.M.C.A"</I> (<B>Village People</B>), <I>"Last Dance"</I> (<B>Donna Summer</B>),
<I>"I Love America"</I> (<B>Patrick Juvet</B>), <I>"Instant Replay"</I> (<B>Dan Hartman</B>) and
<I>"(Push, push) In the Bush"</I> (<B>Musique</B>).<BR>
One fun detail to know about the <A HREF="../tributes/patrick.shtml"><B>Patrick Adams</B></A> act <B>Musique</B>
(with <B>Jocelyn Brown</B> on lead vocals) was that they shot their video for <I>"(Push, Push) In the Bush"</I>,
in the club.<br>
Paolo remembers the music played: <I>"It's still the best dance music around; 'Last Dance', 'I love the
Nightlife', 'Born to be Alive', 'Push, Push in the Bush', I could go on and on... What made the music so
special was the light show that went with it. As the music became more alive, so did the light show."</I>
<P>
<IMG ALIGN=LEFT SRC="../images/studio54jm.jpg" HEIGHT=152 WIDTH=108 ALT="Now everybody can get into Studio 54 - Jeans">
<IMG ALIGN=RIGHT SRC="../images/studio54jw.jpg" HEIGHT=152 WIDTH=108 ALT="Now everybody can get into Studio 54 - Jeans">
Another fun detail is that besides "Le Freak" which originally was a hate song of Studio 54, there were
also many other songs mentioning or referring to this "Disco Mecca"...<BR>
In <B>Dennis Parker</B>'s <I>"New York by night"</I> he sings; <I>"At Studio 54, they're waiting at the door,
can't get in - just can't win... This is N.Y. by night, this is N.Y. by night so get ready for the time of your
life..."</I>.<BR>
<B>Amanda Lear</B> got famous for her song <I>"Fashion Pack"</I> in which she sings; <I>"Hustling at the door
to get into Studio 54... Liza dancing on the floor and Bianca walking through the door"</I>.<BR>
<A HREF="../artists/mick.shtml"><B>Mick Jackson</B></A>, writer of <I>"Blame it on the boogie"</I>, wrote the song
<I>"54th Street"</I> in which he sings about a club in Manhattan, USA where they are dancing in a Studio on 54th
Street...<BR>
As said before, everything related to the club and the Studio 54 name was a big industry. You could even
buy yourself a pair of <B>Studio 54 Jeans</B>. The stitching on the back pockets, which every brand try to
find its own unique one, even said <B>54</B> in the studio's logo style.
<P>
<IMG ALIGN=LEFT SRC="../images/studio54glow.gif" HEIGHT=136 WIDTH=155 ALT="Studio 54 logo by Gilbert Lesser">
<IMG ALIGN=RIGHT SRC="../images/studio54moon.jpg" HEIGHT=237 WIDTH=200 ALT="Man in the moon with his silver spoon">
The name and the special Studio 54 logo became well-known in no time all over the world. The brilliant
logo was designed by a guy named <B>Gilbert Lesser</B>.<BR>
Almost as famous at the logo was this sign of the "Man in the Moon" inhaling cocaine (???) from his
silver spoon that was hanging on the wall in the club. Unfortunately inhaling coke and using other drugs
was quite common in the club, but this wasn't something special for Studio 54. At this time drug abuse
was kind of common in all clubs. Drug use was like a lifestyle back then. Probably all the money and all
the clubs famous and regular guests attracted people selling them.<BR>
Some of the regular guests at Studio 54 were people like <B>Andy Warhol</B>, the designer <B>Halston</B>,
<B>Diana Ross</B>, <B>Liza Minelli</B> and lots and lots of others. Other people seen at the club were;
<B>Elizabeth Taylor</B>, <B>Michael Jackson</B>, <B>Brooke Shields</B>, <B>Warren Beatty</B>, <B>Calvin
Klein</B>, <B>Bianca & Mick Jagger</B>, <B>Salvador Dali</B>, <B>Madonna</B> and <B>Elton John</B>.<BR>
Not all of these famous people had to try to get in through the main entrance. No, there was actually a
VIP entrance on the back side of the club, from 53'rd street. This was the entrance where the staff and
the true VIP's got in.
<P ALIGN=CENTER>
<IMG SRC="../images/54vipticket.jpg" HEIGHT=138 WIDTH=250 ALT="Studio 54 VIP ticket">
</P ALIGN=CENTER>
<P>
As so many Celeb's frequented the club, I had to ask Paolo, who actually had met most of them, if he had
any comments on some of them. Paolo; <I>"Every celebrity was extremely nice. All except Sylvester Stallone.
He was on some sort of ego trip. He had body guards all around his banquet wearing bell bottom jeans with
'Rocky' embroidered on their ass. He didn't want to be bothered by anyone. Not even me, who was his busboy.
He didn't want me in 'his' area cleaning up.<br>
<B>Robin Williams</B> was a hoot.<br>
I danced with <B>Valerie Harper</B> for half an hour, a sweet lady.<br>
<B>Margaux Hemmingway</B> gave me her plastic heart on Valentine's Day. She was there before the club opened
and I got there late that night and there weren't any left. They were part of our costume that night so I
had to have one, so she game me hers'.<br>
I saw a political daughter (I won't name names, but her family is mostly not around any more) wearing
a white t-shirt and baseball cap, snorting cocaine. And I thought, if I had a camera right now, I'd make
a million dollars selling the picture."</I><br>
<SPAN CLASS="dg">Have you got any other special memories of some Celeb's?</span><br>
<IMG ALIGN=RIGHT SRC="../images/54-paolo.jpg" HEIGHT=200 WIDTH=159 ALT="Paolo in 1979">
<I>"Elton John was there one Saturday night and tried to pick up Patrick Taylor, another busboy - who was
straight, and I guess I was the next best thing. He asked me to go to his hotel with him, I said thank you
as it was a Saturday night and only around 1am and told him I had to work all evening. About 5 minutes later,
Michael Overington came over to me, tapped me on my shoulder and told me to go get my things because I was
leaving with Elton John. I did and had a wonderful time. That's all I'll say about that evening.<br>
Liza Minelli cornered me in the employee dressing room and told me that one time she was in a limo going
to do a concert at Madison Square Garden. She was drinking some champagne, and all of a sudden a disco
version of 'Somewhere Over the Rainbow' came on the radio. She said it made her furious and threw the
glass of champagne against the window between the front and back of the limo. She then said she realized
how much the public loved her mother to contemporize the song, she burst into tears and cried all the way
to the concert."</I><br>
Many celeb's kept coming back to '54' and in an interview, <B>August Darnell</B>, cofounder of <B>Dr.
Buzzard's Original Savannah Band</B> and leader of <B>Kid Creole and the Coconuts</B> remembers: <I>"We
used to hang out at Studio 54 so much that we should have been paying rent. In England, now, they have
all these rave parties, but when people say there's nothing like a rave, I say I saw all this in 1977 at
Studio 54. I'd have to say my favorite club was Studio 54, it was so decadent and so exciting in that
period to be part of something you knew was a world movement. The good thing was it gave people a reason
to say 'Let's get dressed up and go out!'"</I>
<P>
<IMG ALIGN=LEFT SRC="../images/studio54-booth.jpg" HEIGHT=143 WIDTH=200 ALT="Studio 54 DJ-booth">
Beside all the famous guests of the Studio 54, the club also managed to get all the best DJ's to play
there as well. All of the famous DJ's like; <A HREF="../tributes/jellybean.shtml"><nobr><B>John "Jellybean"
Benitez</B></nobr></A>, <A HREF="../djs/john-c.shtml"><nobr><B>John Ceglia</B></nobr></A>, <nobr><B>Tony
Humphries</B></nobr>, <A HREF="../djs/sharon.shtml"><nobr><B>Sharon White</B></nobr></A>,
<nobr><B>Kenny Carpenter</B></nobr>, <nobr><B>Robbie Leslie</B></nobr>, <nobr><B>Tony Carrasco</B></nobr> and many
others, moved the crowd from the clubs legendary horseshoe shaped DJ-booth.<BR>
One guy everyone <I>think</I> DJ'ed there, but who was actually never a DJ at all, but who's mixes were <B>always</B>
played in the club, was the legendary remixer <nobr><A HREF="../tributes/tom.shtml"><B>Tom Moulton</B></A>.</nobr>
<P ALIGN=CENTER>
<IMG SRC="../images/54-dancefloor.jpg" HEIGHT=201 WIDTH=300 ALT="Studio 54 - Dancefloor from the DJ booth">
</P ALIGN=CENTER>
<P>
The club had a superb sound system, built and designed by some of the best people in the business - <B>RLA</B>
[Richard Long & Associates]. Richard was also the one who was responsible for the sound system at the <B>Paradise
Garage</B>, a system that still today is said to have been the best system ever in the world.<BR>
<IMG ALIGN=LEFT SRC="../images/studio54-console.jpg" HEIGHT=200 WIDTH=142 ALT="Studio 54 DJ-console">
The equipment at Studio 54 were comprised of 6 3-way "Waldorf" horn loaded/bass reflex main bass boxes, 6 "Bertha/Levan"
bass horns, 4 "Z" tweeter arrays & 2 "Ultima" 3-way full range boxes. This system also included the now famous
RLA X-3000 DJ crossover. This sound system was the reason for this and many other clubs during this era's success.<BR>
Richard is unfortunately no longer with us today, but some of the RLA designs, electronics and speaker boxes are
available from the New York based company <A HREF="http://www.gsany.com" TARGET="_BLANK"><B>GSA</B></A> [Gary Stewart
Audio]. GSA can help you if you're interested in building a sound system similar to the one in '54'.<br>
Also, in the GSA shop they still have a bunch of things from the original Studio 54.<br>
By the way, the original "Man in the Moon" sign is told to be installed in the existing <nobr>Studio 54</nobr>
club in the <nobr><B>MGM Grand</B></nobr> in Las Vegas these days.<br>
<P>
Paolo (Paul-Michael) was hired as a Busboy by the clubs manager - <nobr><B>Michael Overington</B></nobr>. Here
Paolo shares his memories from his years as an employee of Studio 54...<br>
<SPAN CLASS="dg">What did you think of the club itself?</span><br>
<I>"I thought it was amazing. Other than having my son, it was probably the most fun I had in life."</I><br>
<SPAN CLASS="dg">Have you got any memories of club's owners?</span><br>
<I>"Stevie was sweet and always had a Michelob in his hand. He always seemed a little bit drunk or Quaaluded out.
Ian was the silent partner, not around much but I knew who he was. Jack Dushey, the financial backer, I had
never heard of at the time.<br>
Another thing... When I started working there I went up to Stevie every night for two weeks and asked him if he
knew my name. It took him two weeks to get it right. Then he thought that I would sleep with him because he
remembered. I didn't."</I><br>
<SPAN CLASS="dg">How many people were working in the bar?</span><br>
<I>"I would say there were 4 bartenders at the main bar, a few bar-backs, 1 bartender up at the bar in the
lounge. There were probably 5 to 6 busboys on a busy night. Less when it wasn't as crowded. There were 2 busgirls
upstairs in the balcony when I started and they were there for a while. After a while they put in another bar
on the right side of the dance floor, so there was 1 bartender there as well."</I><br>
<SPAN CLASS="dg">Do you recall how many people were working the club at a busy night, all areas?</span><br>
<I>"Yes, there were lots more employees. 2 coat check girls, 1 light man, 1 to 2 people working the pulleys at
the back of the dance floor. The front half of the dance floor lights were electronic, in the back, such as
the moon and the spoon, light poles, etc., were moved up and down on pulley's by 1 to 2 guys. Mark B and Stevie
were up front at the door as well as probably 4 to 6 bouncers."</I><br>
<IMG ALIGN=LEFT SRC="../images/54-paolo-ladyinred.jpg" HEIGHT=250 WIDTH=137 ALT="Paolo dancing with a Lady in Red">
<SPAN CLASS="dg">How many guests were there in a crowded night?</span><br>
<I>"I could only guess on the number of people in the club on a busy night... I'd say around 500, this is only
a guess, could be more, could be less. On a Friday and Saturday night there were probably also around 500 people
outside trying to get in. I do know that if you didn't get picked by the time you walked up to the ropes you
probably did not get it. I would see people walking up to the ropes and when Stevie and/or Mark looked away,
they would stop and walk in place until they looked over again and then continue up to the ropes in the hope
of getting in."</I><br>
<SPAN CLASS="dg">Were most of the employees gay, as you told earlier that Elton tried to pick up a straight
busboy?</span><br>
<I>"Most of the employees were gay. There were a few straight boys mixed in."</I><br>
<SPAN CLASS="dg">So, were there many people trying to pick you up?</span><br>
<I>"Yes, all the time. The busboys were looked upon as like 'playboy bunnies'. Everyone was always trying to
bed us."</I><br>
<SPAN CLASS="dg">The Balcony has become legendary through the '54' movie, any comments on what went on in the
balcony?</span><br>
<I>"Not much went on it the balcony that I was aware of, some making out and a bit more but it was nothing like
the movie."</I><br>
<SPAN CLASS="dg">You must have lots of other memories and stories from the club, anything else you can tell
about?</span><br>
<I>"Well one morning as I was leaving the club, Saturday morning after a Friday night, and as I left through
the back door I opened it and Ian was coming from the right with a 3-ring binder under his arm, and from the left
were 2 men in suits and trench coats. I let them in, closed the door and went home. Ian had a lot of cocaine
and drugs for that Saturday night, he put the binder down on the speaker near the back door thinking that both
the FBI agents would follow him upstairs to look at the books. Only one went with him. The other stayed down
stairs and sat on one of the banquettes at the back of the dance floor. The guy got bored and started flipping
through the binder and found the drugs... And the rest is history."</I><br>
<SPAN CLASS="dg">Have you got any contact with any of your former colleagues at '54'?</span><br>
<I>"I found a website where <B>Sandt Litchfield</B> was listed with some friends, and I tried to contact him
but never heard back.<br>
Mark Beneke seems to be Ian's eyes and years at the Clift Hotel here in San Francisco. I spoke to him and of
course he didn't remember me. He was hot stuff back then and I was just a peon.<br>
I am also in contact with one of the busboy's Jeffrey, he's here in San Francisco as well."</I>
<BR><BR>
</TD>
<TD WIDTH=10><img src="../index/trans.gif" width="10" height="1"></TD>
<TD WIDTH=100>
<span class="songsintro">Download the <B>FREE</B> basic RealPlayer...</span><br><br>
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<BR><BR><BR><BR>
<span class="songsintro">CLICK to hear some <nobr><B>Studio 54</B></nobr> classics...</span><BR><BR>
<span class="songs">
<A HREF="../sounds/mj-54thstreet.ra">54th Street</A><BR>Mick Jackson<BR><BR>
<A HREF="../sounds/badgirls.ra">Bad girls</A><BR>Donna Summer<BR><BR>
<A HREF="../sounds/boss.ra">the Boss</A><BR>Diana Ross<BR><BR>
<A HREF="../sounds/dancex3.ra">Dance, dance, dance</A><BR>Chic<BR><BR>
<A HREF="../sounds/disconight.ra">Disco night (Rock freak)</A><BR>G.Q.<BR><BR>
<A HREF="../sounds/dont-l.ra">Don't leave me this way</A><BR>Thelma Houston<BR><BR>
<A HREF="../sounds/everybod.ra">Everybody dance</A><BR>Chic<BR><BR>
<A HREF="../sounds/flyrobin.ra">Fly Robin Fly</A><BR>Silver Convention<BR><BR>
<A HREF="../sounds/good-t.ra">Good times</A><BR>Chic<BR><BR>
<A HREF="../sounds/havent.ra">Haven't stopped dancing yet</A><BR>Gonzalez<BR><BR>
<A HREF="../sounds/hes-the.ra">He's the greatest dancer</A><BR>Sister Sledge<BR><BR>
<A HREF="../sounds/heart-of.ra">Heart of glass</A><BR>Blondie<BR><BR>
<A HREF="../sounds/hotstuff.ra">Hot stuff</A><BR>Donna Summer<BR><BR>
<A HREF="../sounds/i-got.ra">I got my mind made up</A><BR>Instant Funk<BR><BR>
<A HREF="../sounds/iloveamerica.ra">I love America</A><BR>Patrick Juvet<BR><BR>
<A HREF="../sounds/ilt-nightlife.ra">I love the nightlife (Disco Round)</A><BR>Alicia Bridges<BR><BR>
<A HREF="../sounds/i-will.ra">I will survive</A><BR>Gloria Gaynor<BR><BR>
<A HREF="../sounds/im-coming.ra">I'm coming out</A><BR>Diana Ross<BR><BR>
<A HREF="../sounds/iycrmm.ra">If you could read my mind</A><BR>Viola Wills<BR><BR>
<A HREF="../sounds/in-the.ra">(Push push) In the bush</A><BR>Musique<BR><BR>
<A HREF="../sounds/instant.ra">Instant replay</A><BR>Dan Hartman<BR><BR>
<A HREF="../sounds/keepon.ra">Keep on dancin'</A><BR>Gary's Gang<BR><BR>
<A HREF="../sounds/keep-on.ra">Keep on jumpin'</A><BR>Musique<BR><BR>
<A HREF="../sounds/knock.ra">Knock on wood</A><BR>Amii Stewart<BR><BR>
<A HREF="../sounds/last-d.ra">Last dance</A><BR>Donna Summer<BR><BR>
<A HREF="../sounds/le-freak.ra">Le Freak</A><BR>Chic<BR><BR>
<A HREF="../sounds/lets-all.ra">Let's all chant</A><BR>Michael Zager Band<BR><BR>
<A HREF="../sounds/moveonup.ra">Move on up</A><BR>Destination<BR><BR>
<A HREF="../sounds/native.ra">Native New Yorker</A><BR>Odyssey<BR><BR>
<A HREF="../sounds/new-york.ra">New York by night</A><BR>Dennis Parker<BR><BR>
<A HREF="../sounds/que-sera.ra">Que sera mi vida</A><BR>Gibson Brothers<BR><BR>
<A HREF="../sounds/relight.ra">Relight my fire</A><BR>Dan Hartman<BR><BR>
<A HREF="../sounds/spank.ra">Spank</A><BR>Jimmy "Bo" Horne<BR><BR>
<A HREF="../sounds/takeyour.ra">Take your time (Do it right)</A><BR>S.O.S Band<BR><BR>
<A HREF="../sounds/turn-the-beat.ra">Turn the beat around</A><BR>Vicki Sue Robinson<BR><BR>
<A HREF="../sounds/upside.ra">Upside down</A><BR>Diana Ross<BR><BR>
<A HREF="../sounds/vertigo.ra">Vertigo</A><BR>Dan Hartman<BR><BR>
<A HREF="../sounds/we-are.ra">We are family</A><BR>Sister Sledge<BR><BR>
<A HREF="../sounds/ymca.ra">Y.M.C.A</A><BR>Village People<BR><BR>
<A HREF="../sounds/you-make.ra">You make me feel (Mighty real)</A><BR>Sylvester<BR><BR>
</span>
<BR><BR>
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<span class="cddisc">Volume 1</span><BR>
<span class="cdsongs">Studio 54 - The 54 Allstars<BR>
Keep on dancin' - Gary's Gang<BR>
the Boss - Diana Ross<BR>
Dance dance dance "Yowsah yowsah yowsah" - Chic<BR>
Vertigo / Relight my fire - Dan Hartman<BR>
You make me feel "Mighty real" - Sylvester<BR>
Move on up - Destination<BR>
Love machine (Pt.2) - the Miracles<BR>
Contact - Edwin Starr<BR>
Knock on wood - Mary Griffin<BR>
Let's start the dance - Bohannon<BR>
I got my mind made up - Instant Funk<BR>
Young hearts run free - Candi Staton<BR>
Native New Yorker - Odyssey<BR>
Que sera mi vida - Gibson Brothers<BR>
Wishing on a star - Rose Royce<BR></span>
<span class="cddisc">Volume 2</span><BR>
<span class="cdsongs">If you could read my mind - Stars on 54: Ultra Naté, Amber & Jocelyn Enriquez<BR>
Haven't stopped dancing yet - Gonzalez<BR>
Heaven must have sent you - Bonnie Pointer<BR>
Loving is really my game - Brainstorm<BR>
Disco nights "Rock-freak" - GQ<BR>
Found a cure - Ashford & Simpson<BR>
Don't leave me this way - Thelma Houston<BR>
Come to me - France Joli<BR>
Take your time "Do it right" - S.O.S Band<BR>
Please don't let me be misunderstood - Santa Esmeralda<BR>
Spank - Jimmy "Bo" Horne<BR>
Galaxy - War<BR>
I need a man - Grace Jones<BR>
Heart of glass - Blondie<BR>
Cherchez la femme / Se si bon - Dr. Buzzard's Original Savannah Band<BR>
Fly Robin fly - Silver Convention<BR></span>
<BR><BR>
<IMG SRC="../images/lastdaysofdisco-cd.jpg" HEIGHT=90 WIDTH=90 ALT="Last Days of Disco soundtrack" BORDER="0"><br>
<span class="cdbuy">Click to buy from</span><br>
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<span class="cdsongs">I love the nightlife (Disco 'round) - Alicia Bridges<BR>
I'm coming out - Diana Ross<BR>
Got to be real - Cherel Lynn<BR>
Good times - Chic<BR>
He's the greatest dancer - Sister Sledge<BR>
I don't know it it's right - Evelyn "Champagne" King<BR>
More, more, more (Pt.1) - Andrea True Connection<BR>
Doctor's orders - Carol Douglas<BR>
Everybody dance - Chic
The love I lost - Harold Melvin & the Blue Notes<BR>
Let's all chant - Michael Zager Band<BR>
Got to have loving - Don Ray<BR>
Shame - Evelyn "Champagne" King<BR>
Knock on wood - Amii Stewart<BR>
The oogum boogum song - Brenton Wood<BR>
Love train - O'Jays<BR>
I love the nightlife (Disco 'round) - India & NuYorican Soul<BR></span>
<BR><BR>
<IMG SRC="../images/bb-disco-book-cover.jpg" WIDTH=95 HEIGHT=118 ALT="Disco: The Bill Bernstein Photographs" TITLE="Disco: The Bill Bernstein Photographs" BORDER="0"><BR>
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<span class="cdsongs"><B>Disco: The Bill Bernstein Photographs</B><br>
<A HREF="../disco/bb-disco-book.shtml" target="_blank">Interview with Bill</A><BR></span>
<BR><BR>
<IMG SRC="../images/studio54-legend-book.jpg" HEIGHT=114 WIDTH=90 ALT="Studio 54, the Legend" BORDER="0"><BR>
<span class="cdbuy">Click to buy from</span><BR>
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<span class="cdsongs"><B>Studio 54: the Legend</B><br>
- Written by Anthony Haden-Guest, Niels Kummer and Domitilla Sartogo<BR></span>
<BR><BR>
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<span class="cdbuy">Click cover to buy</span><BR>
<span class="cdsongs"><B>Fabulous!</B> <I>A Photographic diary of Studio54</I><br>
- Photos and writing by Bobby Miller<BR>
- Signed copy $190 + shipping</span>
<BR><BR>
<IMG SRC="../images/54-dvd.jpg" HEIGHT=140 WIDTH=97 ALT="54 - the Movie" BORDER="0"><br>
<span class="cdbuy">Click to buy from</span><br>
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<span class="cdsongs"><B>54 - the Movie</B><br>
- the Movie about this legendary club on DVD<br>
- with Mike Myers, Neve Campbell, Ryan Phillippe and Salma Hayek</span>
<BR><BR>
</TD></TR>
<TR><TD colspan=3>
<P>
Later I got in touch with <B>Miestorm</B>, who was also working along with Paolo and others at <nobr>Studio 54</nobr>.
Miestorm tells me;<br>
<IMG ALIGN=LEFT SRC="../images/54m-miestorm.jpg" HEIGHT=150 WIDTH=131 ALT="Miestorm aka Lenny 54">
<I>"I worked, but mostly played at Studio (as everyone who went there called it), from 1977-1982 and I was known as
<B>Lenny 54</B>. Stevie didn't like the name Miestorm because he said it sounded too foreign and we already had <B>Weego</B>
and Miranda.<br>
I was originally hired as a busboy and bartender, but, I was an entertainer and was instructed by Steve Rubell to wear as
little as possible plus flirt and be as sexy as possible with everyone. The movie '54' was a Disney movie compared to
the real Studio, the place was so decadent that my grandfather (who spoke only Italian) thought I was working in Satans
palace.<br>
During my first few years of working there, Stevie would instruct the security to watch me carfully and report to him
on what drug I was seen taking, if I drank booze and if I was seen having sex with anyone or leaving with whoever. He
wanted to know my every move, so, I would be as bad as possible and he loved it!"</I><br>
Miestorm also sent me some of his own personal <a href="javascript: openWindowSized('studio54-pics.shtml',700,850)"><B>
>> photo's from inside Studio 54 << </B></A>.
<P>
The party went on great for the club and people were saying this was the best thing that had ever happened
and this would last forever... But as everything else, the success story of Studio 54 also had an end.<br>
Jack Dushey had tried to convince Steve & Ian to give up the black economy of the Skim and go legit, but they
just wouldn't listen. Then in 1979 Donald Moon, a former employee who had been "not very tactfully fired"
by Steve, used his knowledge of the black money to turn the Feds and IRS on the owners.<br>
In late spring 1979 Jack approached the feds and pleaded guilty to one single point of tax evasion and in
the end of June Steve and Ian were charged with skimming $2.5 million.<br>
In December of 1979 the IRS arrested Steve and Ian for withholding of taxes and the club was also said to
be a central for cocaine distribution. The two owners never thought they would have to go to jail, but they
were sentenced to three and a half years in prison and in February 1, 1980 they were in behind bars.<br>
After having informed on and turned in some of their ex-partners and competitors they got their time cut
down to 13 months.<BR>
The clubs liquor license expired in February 28, 1980 - just 28 days after Steve & Ian went to jail and a
new license would take 18 months to get. This was devastating to a club like 54: No booze = No guests. And
papers claimed it was <B>Sylvester Stallone</B> who had the last legal drink. Then in March, just days
after the license expired the club died and was closed down.<BR>
The club was then sold to <B>Mark Fleischman</B> who re-opened Studio 54 in September 15, 1981. Steve
and Ian were out of jail and were even working in the club again for a while as consultants, as part of the
deal. But the club never could revive its former popularity and lots of the famous people seen in the studio
before Steve and Ian got busted, were never seen there again. Mark run the place for some four years and
in 1986 he decided to close down the Studio 54.<BR>
Steve and Ian had left long before this to get into the hotel business and they where also involved as
consultants in some nightclub projects. But they never got the same attention as they got at the "original"
Studio 54. And in July 1989 Steve died of AIDS related complications.<BR>
Ian Schrager is still active in the hotel business and owns a chain of 5 star Hotels over the world, called
<B>Ian Schrager Hotels</B>. Among these hotels are the famous <B>Clift Hotel</B> in San Francisco, <B>the
Paramount Hotel</B> in New York, <B>Miramar</B> in Santa Barbara and <B>The Sanderson</B> in London.
<P>
<a href="mailto:troubleblonde@comcast.net?subject=I want to buy Fabulous!"><IMG ALIGN=RIGHT SRC="../images/54-fabulous-book.jpg" HEIGHT=200 WIDTH=134 ALT="BUY - Fabulous - A photographic diary of Studio 54 by Bobby Miller" BORDER=0></A>
Photographer <B>Bobby Miller</B> entered the '54' in its first days and stayed there over the next couple of years,
always with his camera ready, through which he catched all these <I>Fabulous!</I> photos of the people frequenting
the club. His legendary pic's have been seen in lots of magazines all over the world and in this book he has put
some of them together, with his own notes and memories attached to them.<br>
This book is an excellent timeline and it catches the magic of the club's first years and the photos portraits famous
people like <B>Christopher Reeve</B> [actor], <B>Dustin Hoffman</B> [actor], <B>Grace Jones</B> [model & artist],
<B>Elton John</B> [artist], <B>Jerry Hall</B> [model], <B>Yul Brynner</B> [actor], <B>Mikhail Baryshnikov</B> [dancer],
<B>Gloria Swanson</B> [actor], <B>Martha Graham</B> [dancer/choreographer], <B>Eartha Kitt</B> [artist], <B>Olivia
Newton-John</B> [artist actor], <B>Bette Midler</B> [artist] and of course "inventories" like <B>Steve Rubell</B>,
<B>Andy Warhol</B>, <B>Liza Minelli</B>, <B>Disco Sally</B> and <B>Truman Capote</B>. But there are LOTS of other famous
persons as well in the authors <I>Fabulous!</I> book.<br>
Here's your chance to get hold of Bobby's out-of-print book - <B>Fabulous!</B> - <I>A photographic diary of
<B>Studio 54</B></I> [St. Martin's Press]. Bobby himself is offering the viewers of <B>Disco-Disco.com</B>
brand new and signed copies of his wonderful and hard-to-find hardcover book for only $190 + shipping. Note that used
signed copies of this book go for up to $250 on e-bay.<br>
Buy your signed copy of <B>Fabulous!</B><a href="mailto:troubleblonde@comcast.net?subject=I want to buy Fabulous!">
>> <B>Click here!</B> <<</A>.
<P>
What happened to the club? Well it actually became a strip club for a couple of years. But in October, 1994
it was re-reopened as Studio 54 again. For this re-opening the new owners managed to bring in old Disco
stars like <nobr><A HREF="../artists/gloria.shtml"><B>Gloria Gaynor</B></A></nobr>, <nobr><B>Vicki Sue Robinson</B></nobr>
and <nobr><B>Sister Sledge</B></nobr> to perform. The new opening was a success and the club runs for some
months when the owner suddenly took all the money and left. And the club went into bankruptcy in the beginning
of 1995.<BR>
It was said the place would be turned into something else, but the club was still there and it was used for
special occasions. I know for example that people like <nobr><B>Gloria Estefan</B></nobr> made special
performances in the club.<BR>
I was in New York in October, 1998 and I just had to walk by this famous address and at that time
- the 54 logo sign was still there above the entrance. But just some weeks later the sign was torn down and
was replaced by a sign for the 'Cabaret' musical that was playing there for some years.
<P>
<A HREF="../disco/cds.shtml#LDOD" onmouseover="window.status='Last Days of Disco - soundtrack'; return true" onmouseout="window.status=''; return true"><IMG ALIGN=LEFT SRC="../images/lastdaysofdisco-cd.jpg" ALT="Last days of Disco" WIDTH=100 HEIGHT=100 BORDER=0></A>
Since talking 'bout Studio 54... There were 2 movie releases out in 1998 trying to capture the magic and
the great music of this famous Discotheque. One was a film called <nobr><B>The Last Days of Disco</B></nobr> and
it was directed by <B>Whit Stillman</B> (director of "Metropolitan" and "Barcelona"). The story is about
<B>Studio 54</B> in the late 1970's/early 1980's and the people who hang there. The soundtrack, however, is
the star of the film: featured prominently are <I>"Good Times"</I>, <I>"Le Freak"</I> and <I>"Everybody Dance"</I>
by <B>Chic</B>, as well as <I>"I'm Coming Out"</I> by <B>Diana Ross</B> and <I>"He's The Greatest Dancer"</I>
by <B>Sister Sledge</B> and some other classic Disco songs. <B>The film is a veritable
<A HREF="../tributes/chic.shtml">Nile & Bernard</A> tribute in itself!</B><BR>
<A HREF="../disco/cds.shtml#54" onmouseover="window.status='Last Days of Disco - soundtrack'; return true" onmouseout="window.status=''; return true"><IMG ALIGN=RIGHT SRC="../images/54cd.gif" HEIGHT=130 WIDTH=130 ALT="54 - the CD" BORDER=0></A>
The other movie was just called <B>"54"</B> and was the life story of the late Steve Rubell with most attention
on Studio 54. Steve was played by <B>Mike Meyers</B> (Waynes World) and the ever so great <B>Neve Campbell</B>
also had a leading role in the picture together with <B>Lauren Hutton</B>. Some of the scenes for the movie were
actually shot at the original Studio 54, that were some exterior and lobby scenes. With this movie it came no
less than 2 albums with great music, of course there was one <B>Chic</B> track - <I>"Dance, dance, dance"</I>.
Other of the great Disco songs on the albums were; <I>"Keep on dancin'"</I> (<B>Gary's Gang</B>), <I>"the Boss"</I>
(<B>Diana Ross</B>), <I>"Vertigo/Relight my fire"</I> (<B>Dan Hartman</B> R.I.P), <I>"Move on up"</I>
(<B>Destination</B>), <I>"I got my mind made up"</I> (<B>Instant Funk</B>), <I>"Don't leave me this way"</I>
(<B>Thelma Houston</B>), <I>"Come to me"</I> (<B>France Joli</B>), <I>"Take your time - do it right"</I>
(<B>S.O.S Band</B>), <I>"Spank"</I> (<B>Jimmy "Bo" Horne</B>) and <I>"Heart of glass"</I> (<B>Blondie</B>).<BR>
With the <B>"54"</B> album came also the new hit <I>"If you could read my mind"</I> by <B>Stars on 54</B>. A
constellation of <B>Ultra Naté</B>, <B>Amber</B> and <B>Jocelyn Enriquez</B>. This is actually a cover of an
old <B>Viola Wills</B> song with the same name.<br>
Many people has also asked about an instrumental song that is played about 7 minutes into the movie, just when Shane
enters the club for the first time. The song is <I>"the Break"</I> by <B>Kat-Mandu</B> and it's not featured in any
of the two soundtrack CD's.
<P>
<IMG ALIGN=LEFT SRC="../images/nycboy.jpg" HEIGHT=125 WIDTH=125 ALT="Pet Shop Boys - New York City Boy">
VERY inspired by the <B>"54"</B> movie was <B>Pet Shop Boys</B>' video to their hit song <I>"New York City Boy"</I>,
released in October 1999. The storyline is similar to the movie - This guy dreams about going to Manhattan and to the
Studio 54. Finally he gets there and everyone is there, Bianca Jagger on her white horse, Andy Warhol - yes, everything
you could expect. It's a great video. The song itself is (according to the guys) a tribute to <B>Village People</B>
and it is really breathing classic DISCO. The "Boys" have been working with famous remixer <B>David Morales</B> and
together they have made a GREAT song!<BR>
It's not only the Pet Shop Boys who has been inspired by this legendary club. Even <B>Madonna</B>'s 2006 world tour -
the <I>Confessions Tour</I> will be a celebration to the club and the Disco lifestyle. It has been announced that
Madonna will be recreating hedonistic scenes from the notorious nightclub in a stage set for her tour along with loads
of Disco mirror balls. '54' will make a great background set for her Disco influenced music from her most danceable
release for a long time, the <B>Confessions on a Dance floor</B> album.<br>
Madonna first performed in the legendary club in 1983 in a party for the Italian fashion house, <B>Fiorucci</B>. At that
time she remarked to actor <B>David Alan Grier</B>: <SPAN CLASS="quote">"You and me are going to be big stars, baby,
and leave these other suckers in the dust."</SPAN> Indeed she did, and it seems the wheel has come full circle when
she now, 20+ years later, return to <nobr>Studio 54</nobr> where part of her success started.
<P>
<CENTER>
<A HREF="../sounds/studio54-2.ra" OnClick="openWindowSized('studio54-mix2.shtml',450,600)" onMouseOver="self.status='Old night at Studio54 - part 2';return true" onMouseOut="self.status=' ';return true"><IMG SRC="../images/dj.gif" BORDER=0></A><BR>
<A HREF="../sounds/studio54-2.ra" OnClick="openWindowSized('studio54-mix2.shtml',450,600)" onMouseOver="self.status='Old night at Studio54 - part 2';return true" onMouseOut="self.status=' ';return true">Another Studio 54 DJ mix</A>
</CENTER>
<P>
Even though Steve Rubell and Ian Schrager's empire only lasted for 33 months it was an orgy in music, money,
glamour and drugs. There were endless number of unforgettable parties and all the "right" people were there.<BR>
<B>Studio 54</B> is an Icon of the Disco era and it was without any doubt as important to Disco as the engine
is to a car, without it - it wouldn't run. The club was the Center of the Disco Universe, along with some other
clubs and of course all the great artists and labels whom the club would have been nothing without. But without
clubs like Studio 54 the whole Disco era wouldn't probably have been as huge as it really was. The suites of this
great era still influence the music and nightlife today. The Disco era set the standards for the clublife and
music today.<BR>
Many people have wanted to open up the club again and in May/June of 2001 part of the legendary club was re-opened
as <nobr><B>Upstairs at Studio 54</B></nobr>.<BR>
It's the former balcony which, back in the clubs later days, were strictly celeb's only that has been turned into
a club again. Saturdays at the club has been told to be among the best places in town.<BR>
Again, it's not the complete legendary club that's re-opened and the space has been used for conferences and special
appearances as well as a theatre. The Broadway success <B>Cabaret</B> was played there for a long time and in April
2005 <B>A Streetcar Named Desire</B> was set up in the former club.
<P>
<P ALIGN=CENTER>
This was the story about THE most famous club of all times...<BR><BR>
<SPAN class="name">Studio 54</span><br>
<SPAN class="bigbold">the Center of the Disco Universe!</span>
</P ALIGN=CENTER>
</TD></TR>
</TABLE>
<br><br><br>
<SPAN class="thanks">Discuss <SPAN class="header3">Studio 54</SPAN> in the <a href="http://www.disco-disco.com/forum/viewforum.php?f=11" TARGET="_blank"><B>FORUM</B></A></SPAN><br><br>
<SPAN class="thanks">View <SPAN class="header3">Studio 54</SPAN> <a href="javascript: openWindowSized('studio54-pics.shtml',700,850)"><B>photos and invites</B></A>.</SPAN>
<br><br><br>
<span class="copyright">© Discoguy (<a href="mailto:discoguy@disco-disco.com">discoguy@disco-disco.com</a>) 1999-2021.<br>
All rights reserved.<br>
No part of these pages may be reproduced or published without the prior written permission of the author.</span>
<P>
<span class="thanks"><B>BIG THANKS</B><BR>
to Paolo & Miestorm<br>
for input, memories and for Miestorm's photos !!!</span>
<P>
<IMG SRC="../images/colorbar.gif">
<P>
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Studio 54 @ Disco-Disco.com
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This is the....
# Studio 54
![Studio 54 logo](../images/studio54.gif)
254 West 54th Street, New York, New York
One of THE DISCOtheques...
Welcome to the Party!
I'm looking for **Studio 54** stuff like:
Invitations, Memorablia, DJ Tapes & Photos
Even Invitation/Flyer scans are wanted...
HAVE YOU GOT ANY ?
Please...
[![](../images/email2.gif)
Mail ME !](mailto:discoguy@disco-disco.com)
![](../images/colorbar.gif)
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In April 26, 1977 - just off Broadway, at 254 W. 54'th Street, Manhattan, New York - THE most
well-known Disco of all times opened up its doors for the very first time. The club would soon
become the "home" of the rich, the famous and the fashion pack. The club was (of course) -
**Studio 54**.
But... Even before the club and its prominent guests "moved in", this now legendary address was
already the home of one of the world's greatest Disco labels - [**West
End Records**](../labels/westend.shtml).
[Have the Studio 54 DJ mix for you](../sounds/studio54-1.ra)
The Club was located in an old theatre and TV studio. In 1927, when the building was just built
it was the home of the "San Carlo Opera Company". It was then followed by theatres like "the New
Yorker", "Casino the Paris", "Federal Music Theatre" to finally in 1943 become a TV studio of
Columbia Broadcasting Co. (CBS). CBS used the place as a soundstage for radio and television
and from this studio successful shows like the *Johnny Carson show*, *Beat the clock*
and *$64000 question* were broadcasted. The CBS people called the place **Studio 52**,
since it was their 52'nd studio (and it was not called Studio 53 as stated by many sources').
Because of the premises former use as a TV studio the name for the new club was first meant to be
just **the Studio**, but since it was used to be called Studio 52 by CBS and it was located
in W. 54'th Street someone came up with the name **Studio 54**. The choice wasn't hard - this
WAS the name!!!
CBS Studio 52 ticket
Steve Rubell and Ian Schrager
Many people had been interested in turning the old theatre into a nightclub. But it wasn't
until the two (to become) owners, **Steve Rubell** and **Ian Schrager**, saw the place
something really happened. They loved the place at once and only a week after they first saw it they
had signed the lease.
Both Steve and Ian had been working in the nightclub business before they managed to hit it off big
time with "the Studio". They had also been in the restaurant business for a long time and they currently
owned a club in Queens, called the **Enchanted Garden**.
In the Enchanted Garden Steve and Ian had a very talented DJ playing, a guy who is the pioneer DJ -
[**Nicky Siano**](../djs/nicky.shtml). Nicky started playing at Steve and Ian's club in
1976 and about two weeks before they opened up Studio 54 they hired Nicky as one of the new clubs
two resident DJ's. The other resident DJ was a guy called [**Richie Kaczor**](../djs/richie.shtml).
Steve and Ian also had a third partner, **Jack Dushey**, who was a professional retailer and in real estate.
He was the new club's financial backer.
Ian and Steve had first met Jack in early 1976 when he held his kids Bar Mitzvah in their club - Enchanted Garden.
The guys had started talking and they told Jack they wanted to open up a club in Manhattan. Jack, as the real
estate man he was, said he was interested in being part of that.
When Rubell and Schrager had found the location they approached Dushey again and he gave the guys a couple of
hundred thousand dollars and said; *"Take the money and I'll get 50% of the net profit."*
Demolition and construction work took about a year and by the time Studio 54 opened, some $600'000 -
$700'000 had been spent to get the place ready to party.
For the Premier night of the Studio 54 the guys hired this girl and party promoter named
**Carmen D'Alessio** to invite the "right" people for the grand opening. Steve and Ian had met
her at their former partner **Maurice Brahms**' club **Infinity**. Carmen got the job as the new
clubs PR manager and she had also been working with Steve and Ian earlier at the Enchanted Garden.
Time went closer and closer to the opening night, some 5000 invitations were out and people were
working day and night to get the place ready in time...
Then in April 26, 1977 - THE day was there. People were still working in the club when some of the
invited people started gathering outside the club. And about half an hour late the club opened up its
doors for the first time. There weren't much people entering at this "early" hour, but within a
couple of hours the place was crowded and outside the doors it was chaos. Even people with invitations
couldn't get in!
|
|
Studio 54 - Dance floor
Studio 54 - Dance floor
The club was huge, about 100 meters long and 80 meters wide, but it still had its theatrical feel, not only
by the spectacular people who went there, but also because of the balcony and stage was still there. In the
balcony there were sitting areas with tables and beneath the balcony was the huge parquet dance floor with all
its strobe-lit columns that descended from the ceiling and its pumping music. Around the dance floor there
were silver banquettes and the mirrored diamond-shaped main bar was located under the balconies, close to the
dance floor.
Studio 54 - the Rubber Room
At the top of the club, in the 3rd floor, overlooking both the balcony and the huge dance floor was the infamous
**Rubber room**. The room had a High-Tec bar and was designed with thick rubber on the walls to be easily washed
down with water and soap after all the sex and drugs going on up there. Some people used to refer to the Rubber room
as "Upstairs", but there were actually more secret places above the Rubber room were more private sex took place.
Those areas were the real "Upstairs" to the initiated.
In the ceiling above the dance floor there were cat walks for the maintenance of the lightning. It's said that the
owners used to spend a great deal of time up there doing drugs and having sex above the heads of the hundreds of
dancing people beneath.
In the basement was the room not anyone could enter - **the VIP room**.
I [**Discoguy**] got a chance to talk to **Paolo Miranda**, who started working
as Busboy, and later Head Busboy, in the club in July of 1978 and was there for about 2 years. Paolo, or Paul-Michael
as he was called back then, fills me in on the VIP lounge...
*"I wouldn't really call it a VIP lounge, it was the basement. There were wire chain link fences all around with
all the supplies for special decorations behind them. There was an Elton John pinball machine down there and a few
white plastic lawn chairs. But I was down there all the time. Also there was the 2-year anniversary party down there,
full of lots of celebrities."*
Studio 54 DJ - Richie Kaczor
Richie Kaczor was the DJ playing this opening night and the first song he played was *"Devil's gun"*
by **C.J. & Co.**. Richie was also the DJ playing in the weekends and Nicky Siano played the second
night and in the weeknights. Nicky couldn't play weekends at "the Studio" since he owned his own
popular New York club - **the Gallery** and was playing there in the weekends. It was also Nicky
who played the night of the famous **Bianca Jagger** birthday bash in May 1977, in which she rode
into the club on a white horse led by a naked body-painted guy.
What's surprising is that while a DJ like [**Larry Levan**](../tributes/larry.shtml) was
well-known among the crowd of the [**Paradise Garage**](paradise.shtml), not many people
knew the names of the resident DJ's of Studio 54.
Paolo adds about the DJ's: *"Richie Kaczor was **THE DJ** during the time I worked there. He was
truly amazing. He would blend a song for a good 10 minutes. It was seamless. You would never know the
song changed. Now a days, they blend for about 10 to 30 seconds and not very good. I got really spoiled
at 54."*
Nicky worked at Studio 54 for about half a year, then he actually got fired because he preferred to spend
hours in the bathroom getting high on drugs instead of getting high on playing records in the DJ booth.
This Nicky told me himself when I got the chance to speak to him, but for the record I also wanna tell
that he stopped taking drugs many many years ago.
Nicky also had so many memories from the Studio that it would take a whole book to tell it all,
but when he played the famous Birthday bash for **Bianca Jagger** was probably his most precious
memory. That night was really a blast, he told me.
He also told me a little about the owners of Studio 54, Steve and Ian. *"Steve was straight when
I met him...? Ian was always the level headed business man, and he was straight, all the time...
I love them both, Steve and Ian were really good to me, and I will always consider them great
supporters and friends."*
He thinks a little more and continues; *"Yes, there was also this celebrity lounge at 54 that made
Sodom and Gomorra look like kindergarten!"* (the VIP lounge!)
People hoping to get into Studio 54
The Studio also had it own door policy, they wanted to get a perfect mix of people which actually
meant that even celebrities was stopped at the door and didn't get in.
This young guy, **Marc Benecke** ruled the door and was instructed by Steve to mix a perfect salad
every night. That way it didn't really matter if you were famous or not - you just had to fit it at this
time.
The doorman Marc even became more famous to the guests of the 54 than Ian Schrager.
Steve was also often in the entrance selecting people to let in and it's said that Steve once didn't like
the shirt a guy was wearing. He told the guy he wouldn't get in with that shirt on, the guy asked if he
could get in if he took it off. Steve said yes and the guy took it off and was allowed to enter the club,
bare-chested.
So it was basically just a question of matching what Steve and Marc were looking for to add to their salad for
the night.
Some people tried desperately to get in and there's actually another true story about this guy who
got stuck in the air duct in his attempt to enter the club - one way or another...
I asked Paolo about the 'salad' door policy and as he says; *"It's what made the club so popular.
Working there meant I had no worries, and it made me feel special at the time."*
Not matching the 'salad of the day' was what happened to **Nile Rodgers** and **Bernard Edwards** of
[**Chic**](../tributes/chic.shtml), when the guys were contacted by **Grace Jones**
who wanted to work with them for her next album...
Grace invited them as her guests to her gig down at the Studio 54. It was New Years Eve in 1977, the
guys were all dressed up and it was snowing and freezing cold... When Nile and Bernard got to the club
the doormen couldn't find their names on the guest list. Nile and Bernard explained that they "were"
Chic and that Grace was expecting them. But the doormen just wouldn't let them in...
In anger they went back home to Nile and in just 25-30 minutes they wrote a whole song they called
"Fuck off". It went like this... "aaahh Fuck off". They just know this was a hit song and they (of
course) had to change the title to be able to release it. So they changed the text and that line to
"aaahh Freak out" and their biggest hit was a fact - *"Le Freak"*. The song topped the US charts
for 6 weeks and *"Le Freak"* became Atlantic Records biggest selling single ever. It also became
the 3'rd biggest single in the music history. It's still the most sold record ever in Canada and the
single sold over 6 million copies only in the US. But after 6 million copies sold of the single, Nile
and Bernard choose to stop the single to not have it cut down the album sales. Who knows how big it
would have become if they hadn't stopped it!?
But Nile and Bernard got their revenge... About one year later to this episode at Studio 54, everything
related to the club and its name was a big industry and at this time Ian & Steve were credited as
Executive Producers of this [**Casablanca Records**](../labels/casablanca.shtml) double LP called
*A night at Studio 54*. The top tune and first song out of this album was no less than - *"Le Freak"*.
Ian & Steve thanked their guests like this in the album; *"To all our guests at Studio 54, whose energy
made this record possible... Our sincere Thanks!"*
Beside the great Chic track the album included other great Disco songs regularly played in the club like;
*"I Love the Nightlife (Disco round)"* (**Alicia Bridges**), *"Let's All Chant"* (**Michael
Zager Band**), *"Y.M.C.A"* (**Village People**), *"Last Dance"* (**Donna Summer**),
*"I Love America"* (**Patrick Juvet**), *"Instant Replay"* (**Dan Hartman**) and
*"(Push, push) In the Bush"* (**Musique**).
One fun detail to know about the [**Patrick Adams**](../tributes/patrick.shtml) act **Musique**
(with **Jocelyn Brown** on lead vocals) was that they shot their video for *"(Push, Push) In the Bush"*,
in the club.
Paolo remembers the music played: *"It's still the best dance music around; 'Last Dance', 'I love the
Nightlife', 'Born to be Alive', 'Push, Push in the Bush', I could go on and on... What made the music so
special was the light show that went with it. As the music became more alive, so did the light show."*
Now everybody can get into Studio 54 - Jeans
Now everybody can get into Studio 54 - Jeans
Another fun detail is that besides "Le Freak" which originally was a hate song of Studio 54, there were
also many other songs mentioning or referring to this "Disco Mecca"...
In **Dennis Parker**'s *"New York by night"* he sings; *"At Studio 54, they're waiting at the door,
can't get in - just can't win... This is N.Y. by night, this is N.Y. by night so get ready for the time of your
life..."*.
**Amanda Lear** got famous for her song *"Fashion Pack"* in which she sings; *"Hustling at the door
to get into Studio 54... Liza dancing on the floor and Bianca walking through the door"*.
[**Mick Jackson**](../artists/mick.shtml), writer of *"Blame it on the boogie"*, wrote the song
*"54th Street"* in which he sings about a club in Manhattan, USA where they are dancing in a Studio on 54th
Street...
As said before, everything related to the club and the Studio 54 name was a big industry. You could even
buy yourself a pair of **Studio 54 Jeans**. The stitching on the back pockets, which every brand try to
find its own unique one, even said **54** in the studio's logo style.
Studio 54 logo by Gilbert Lesser
Man in the moon with his silver spoon
The name and the special Studio 54 logo became well-known in no time all over the world. The brilliant
logo was designed by a guy named **Gilbert Lesser**.
Almost as famous at the logo was this sign of the "Man in the Moon" inhaling cocaine (???) from his
silver spoon that was hanging on the wall in the club. Unfortunately inhaling coke and using other drugs
was quite common in the club, but this wasn't something special for Studio 54. At this time drug abuse
was kind of common in all clubs. Drug use was like a lifestyle back then. Probably all the money and all
the clubs famous and regular guests attracted people selling them.
Some of the regular guests at Studio 54 were people like **Andy Warhol**, the designer **Halston**,
**Diana Ross**, **Liza Minelli** and lots and lots of others. Other people seen at the club were;
**Elizabeth Taylor**, **Michael Jackson**, **Brooke Shields**, **Warren Beatty**, **Calvin
Klein**, **Bianca & Mick Jagger**, **Salvador Dali**, **Madonna** and **Elton John**.
Not all of these famous people had to try to get in through the main entrance. No, there was actually a
VIP entrance on the back side of the club, from 53'rd street. This was the entrance where the staff and
the true VIP's got in.
Studio 54 VIP ticket
As so many Celeb's frequented the club, I had to ask Paolo, who actually had met most of them, if he had
any comments on some of them. Paolo; *"Every celebrity was extremely nice. All except Sylvester Stallone.
He was on some sort of ego trip. He had body guards all around his banquet wearing bell bottom jeans with
'Rocky' embroidered on their ass. He didn't want to be bothered by anyone. Not even me, who was his busboy.
He didn't want me in 'his' area cleaning up.
**Robin Williams** was a hoot.
I danced with **Valerie Harper** for half an hour, a sweet lady.
**Margaux Hemmingway** gave me her plastic heart on Valentine's Day. She was there before the club opened
and I got there late that night and there weren't any left. They were part of our costume that night so I
had to have one, so she game me hers'.
I saw a political daughter (I won't name names, but her family is mostly not around any more) wearing
a white t-shirt and baseball cap, snorting cocaine. And I thought, if I had a camera right now, I'd make
a million dollars selling the picture."*
Have you got any other special memories of some Celeb's?
Paolo in 1979
*"Elton John was there one Saturday night and tried to pick up Patrick Taylor, another busboy - who was
straight, and I guess I was the next best thing. He asked me to go to his hotel with him, I said thank you
as it was a Saturday night and only around 1am and told him I had to work all evening. About 5 minutes later,
Michael Overington came over to me, tapped me on my shoulder and told me to go get my things because I was
leaving with Elton John. I did and had a wonderful time. That's all I'll say about that evening.
Liza Minelli cornered me in the employee dressing room and told me that one time she was in a limo going
to do a concert at Madison Square Garden. She was drinking some champagne, and all of a sudden a disco
version of 'Somewhere Over the Rainbow' came on the radio. She said it made her furious and threw the
glass of champagne against the window between the front and back of the limo. She then said she realized
how much the public loved her mother to contemporize the song, she burst into tears and cried all the way
to the concert."*
Many celeb's kept coming back to '54' and in an interview, **August Darnell**, cofounder of **Dr.
Buzzard's Original Savannah Band** and leader of **Kid Creole and the Coconuts** remembers: *"We
used to hang out at Studio 54 so much that we should have been paying rent. In England, now, they have
all these rave parties, but when people say there's nothing like a rave, I say I saw all this in 1977 at
Studio 54. I'd have to say my favorite club was Studio 54, it was so decadent and so exciting in that
period to be part of something you knew was a world movement. The good thing was it gave people a reason
to say 'Let's get dressed up and go out!'"*
Studio 54 DJ-booth
Beside all the famous guests of the Studio 54, the club also managed to get all the best DJ's to play
there as well. All of the famous DJ's like; [**John "Jellybean"
Benitez**](../tributes/jellybean.shtml), [**John Ceglia**](../djs/john-c.shtml), **Tony
Humphries**, [**Sharon White**](../djs/sharon.shtml),
**Kenny Carpenter**, **Robbie Leslie**, **Tony Carrasco** and many
others, moved the crowd from the clubs legendary horseshoe shaped DJ-booth.
One guy everyone *think* DJ'ed there, but who was actually never a DJ at all, but who's mixes were **always**
played in the club, was the legendary remixer [**Tom Moulton**](../tributes/tom.shtml).
Studio 54 - Dancefloor from the DJ booth
The club had a superb sound system, built and designed by some of the best people in the business - **RLA**
[Richard Long & Associates]. Richard was also the one who was responsible for the sound system at the **Paradise
Garage**, a system that still today is said to have been the best system ever in the world.
Studio 54 DJ-console
The equipment at Studio 54 were comprised of 6 3-way "Waldorf" horn loaded/bass reflex main bass boxes, 6 "Bertha/Levan"
bass horns, 4 "Z" tweeter arrays & 2 "Ultima" 3-way full range boxes. This system also included the now famous
RLA X-3000 DJ crossover. This sound system was the reason for this and many other clubs during this era's success.
Richard is unfortunately no longer with us today, but some of the RLA designs, electronics and speaker boxes are
available from the New York based company [**GSA**](http://www.gsany.com) [Gary Stewart
Audio]. GSA can help you if you're interested in building a sound system similar to the one in '54'.
Also, in the GSA shop they still have a bunch of things from the original Studio 54.
By the way, the original "Man in the Moon" sign is told to be installed in the existing Studio 54
club in the **MGM Grand** in Las Vegas these days.
Paolo (Paul-Michael) was hired as a Busboy by the clubs manager - **Michael Overington**. Here
Paolo shares his memories from his years as an employee of Studio 54...
What did you think of the club itself?
*"I thought it was amazing. Other than having my son, it was probably the most fun I had in life."*
Have you got any memories of club's owners?
*"Stevie was sweet and always had a Michelob in his hand. He always seemed a little bit drunk or Quaaluded out.
Ian was the silent partner, not around much but I knew who he was. Jack Dushey, the financial backer, I had
never heard of at the time.
Another thing... When I started working there I went up to Stevie every night for two weeks and asked him if he
knew my name. It took him two weeks to get it right. Then he thought that I would sleep with him because he
remembered. I didn't."*
How many people were working in the bar?
*"I would say there were 4 bartenders at the main bar, a few bar-backs, 1 bartender up at the bar in the
lounge. There were probably 5 to 6 busboys on a busy night. Less when it wasn't as crowded. There were 2 busgirls
upstairs in the balcony when I started and they were there for a while. After a while they put in another bar
on the right side of the dance floor, so there was 1 bartender there as well."*
Do you recall how many people were working the club at a busy night, all areas?
*"Yes, there were lots more employees. 2 coat check girls, 1 light man, 1 to 2 people working the pulleys at
the back of the dance floor. The front half of the dance floor lights were electronic, in the back, such as
the moon and the spoon, light poles, etc., were moved up and down on pulley's by 1 to 2 guys. Mark B and Stevie
were up front at the door as well as probably 4 to 6 bouncers."*
Paolo dancing with a Lady in Red
How many guests were there in a crowded night?
*"I could only guess on the number of people in the club on a busy night... I'd say around 500, this is only
a guess, could be more, could be less. On a Friday and Saturday night there were probably also around 500 people
outside trying to get in. I do know that if you didn't get picked by the time you walked up to the ropes you
probably did not get it. I would see people walking up to the ropes and when Stevie and/or Mark looked away,
they would stop and walk in place until they looked over again and then continue up to the ropes in the hope
of getting in."*
Were most of the employees gay, as you told earlier that Elton tried to pick up a straight
busboy?
*"Most of the employees were gay. There were a few straight boys mixed in."*
So, were there many people trying to pick you up?
*"Yes, all the time. The busboys were looked upon as like 'playboy bunnies'. Everyone was always trying to
bed us."*
The Balcony has become legendary through the '54' movie, any comments on what went on in the
balcony?
*"Not much went on it the balcony that I was aware of, some making out and a bit more but it was nothing like
the movie."*
You must have lots of other memories and stories from the club, anything else you can tell
about?
*"Well one morning as I was leaving the club, Saturday morning after a Friday night, and as I left through
the back door I opened it and Ian was coming from the right with a 3-ring binder under his arm, and from the left
were 2 men in suits and trench coats. I let them in, closed the door and went home. Ian had a lot of cocaine
and drugs for that Saturday night, he put the binder down on the speaker near the back door thinking that both
the FBI agents would follow him upstairs to look at the books. Only one went with him. The other stayed down
stairs and sat on one of the banquettes at the back of the dance floor. The guy got bored and started flipping
through the binder and found the drugs... And the rest is history."*
Have you got any contact with any of your former colleagues at '54'?
*"I found a website where **Sandt Litchfield** was listed with some friends, and I tried to contact him
but never heard back.
Mark Beneke seems to be Ian's eyes and years at the Clift Hotel here in San Francisco. I spoke to him and of
course he didn't remember me. He was hot stuff back then and I was just a peon.
I am also in contact with one of the busboy's Jeffrey, he's here in San Francisco as well."*
| | Download the **FREE** basic RealPlayer...
[Download the FREE RealPlayer](http://www.real.com)
CLICK to hear some **Studio 54** classics...
[54th Street](../sounds/mj-54thstreet.ra)Mick Jackson
[Bad girls](../sounds/badgirls.ra)Donna Summer
[the Boss](../sounds/boss.ra)Diana Ross
[Dance, dance, dance](../sounds/dancex3.ra)Chic
[Disco night (Rock freak)](../sounds/disconight.ra)G.Q.
[Don't leave me this way](../sounds/dont-l.ra)Thelma Houston
[Everybody dance](../sounds/everybod.ra)Chic
[Fly Robin Fly](../sounds/flyrobin.ra)Silver Convention
[Good times](../sounds/good-t.ra)Chic
[Haven't stopped dancing yet](../sounds/havent.ra)Gonzalez
[He's the greatest dancer](../sounds/hes-the.ra)Sister Sledge
[Heart of glass](../sounds/heart-of.ra)Blondie
[Hot stuff](../sounds/hotstuff.ra)Donna Summer
[I got my mind made up](../sounds/i-got.ra)Instant Funk
[I love America](../sounds/iloveamerica.ra)Patrick Juvet
[I love the nightlife (Disco Round)](../sounds/ilt-nightlife.ra)Alicia Bridges
[I will survive](../sounds/i-will.ra)Gloria Gaynor
[I'm coming out](../sounds/im-coming.ra)Diana Ross
[If you could read my mind](../sounds/iycrmm.ra)Viola Wills
[(Push push) In the bush](../sounds/in-the.ra)Musique
[Instant replay](../sounds/instant.ra)Dan Hartman
[Keep on dancin'](../sounds/keepon.ra)Gary's Gang
[Keep on jumpin'](../sounds/keep-on.ra)Musique
[Knock on wood](../sounds/knock.ra)Amii Stewart
[Last dance](../sounds/last-d.ra)Donna Summer
[Le Freak](../sounds/le-freak.ra)Chic
[Let's all chant](../sounds/lets-all.ra)Michael Zager Band
[Move on up](../sounds/moveonup.ra)Destination
[Native New Yorker](../sounds/native.ra)Odyssey
[New York by night](../sounds/new-york.ra)Dennis Parker
[Que sera mi vida](../sounds/que-sera.ra)Gibson Brothers
[Relight my fire](../sounds/relight.ra)Dan Hartman
[Spank](../sounds/spank.ra)Jimmy "Bo" Horne
[Take your time (Do it right)](../sounds/takeyour.ra)S.O.S Band
[Turn the beat around](../sounds/turn-the-beat.ra)Vicki Sue Robinson
[Upside down](../sounds/upside.ra)Diana Ross
[Vertigo](../sounds/vertigo.ra)Dan Hartman
[We are family](../sounds/we-are.ra)Sister Sledge
[Y.M.C.A](../sounds/ymca.ra)Village People
[You make me feel (Mighty real)](../sounds/you-make.ra)Sylvester
54 - Soundtrack Volume 1
Volume 1Click to buy from
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54 - Soundtrack Volume 2
Volume 2Click to buy from
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Volume 1
Studio 54 - The 54 Allstars
Keep on dancin' - Gary's Gang
the Boss - Diana Ross
Dance dance dance "Yowsah yowsah yowsah" - Chic
Vertigo / Relight my fire - Dan Hartman
You make me feel "Mighty real" - Sylvester
Move on up - Destination
Love machine (Pt.2) - the Miracles
Contact - Edwin Starr
Knock on wood - Mary Griffin
Let's start the dance - Bohannon
I got my mind made up - Instant Funk
Young hearts run free - Candi Staton
Native New Yorker - Odyssey
Que sera mi vida - Gibson Brothers
Wishing on a star - Rose Royce
Volume 2
If you could read my mind - Stars on 54: Ultra Naté, Amber & Jocelyn Enriquez
Haven't stopped dancing yet - Gonzalez
Heaven must have sent you - Bonnie Pointer
Loving is really my game - Brainstorm
Disco nights "Rock-freak" - GQ
Found a cure - Ashford & Simpson
Don't leave me this way - Thelma Houston
Come to me - France Joli
Take your time "Do it right" - S.O.S Band
Please don't let me be misunderstood - Santa Esmeralda
Spank - Jimmy "Bo" Horne
Galaxy - War
I need a man - Grace Jones
Heart of glass - Blondie
Cherchez la femme / Se si bon - Dr. Buzzard's Original Savannah Band
Fly Robin fly - Silver Convention
Last Days of Disco soundtrack
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I love the nightlife (Disco 'round) - Alicia Bridges
I'm coming out - Diana Ross
Got to be real - Cherel Lynn
Good times - Chic
He's the greatest dancer - Sister Sledge
I don't know it it's right - Evelyn "Champagne" King
More, more, more (Pt.1) - Andrea True Connection
Doctor's orders - Carol Douglas
Everybody dance - Chic
The love I lost - Harold Melvin & the Blue Notes
Let's all chant - Michael Zager Band
Got to have loving - Don Ray
Shame - Evelyn "Champagne" King
Knock on wood - Amii Stewart
The oogum boogum song - Brenton Wood
Love train - O'Jays
I love the nightlife (Disco 'round) - India & NuYorican Soul
Disco: The Bill Bernstein Photographs
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**Disco: The Bill Bernstein Photographs**
[Interview with Bill](../disco/bb-disco-book.shtml)
Studio 54, the Legend
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**Studio 54: the Legend**
- Written by Anthony Haden-Guest, Niels Kummer and Domitilla Sartogo
[BUY - Fabulous - A photographic diary of Studio 54 by Bobby Miller](mailto:troubleblonde@comcast.net?subject=I want to buy Fabulous!)
Click cover to buy
**Fabulous!** *A Photographic diary of Studio54*
- Photos and writing by Bobby Miller
- Signed copy $190 + shipping
54 - the Movie
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**54 - the Movie**
- the Movie about this legendary club on DVD
- with Mike Myers, Neve Campbell, Ryan Phillippe and Salma Hayek
|
|
Later I got in touch with **Miestorm**, who was also working along with Paolo and others at Studio 54.
Miestorm tells me;
Miestorm aka Lenny 54
*"I worked, but mostly played at Studio (as everyone who went there called it), from 1977-1982 and I was known as
**Lenny 54**. Stevie didn't like the name Miestorm because he said it sounded too foreign and we already had **Weego**
and Miranda.
I was originally hired as a busboy and bartender, but, I was an entertainer and was instructed by Steve Rubell to wear as
little as possible plus flirt and be as sexy as possible with everyone. The movie '54' was a Disney movie compared to
the real Studio, the place was so decadent that my grandfather (who spoke only Italian) thought I was working in Satans
palace.
During my first few years of working there, Stevie would instruct the security to watch me carfully and report to him
on what drug I was seen taking, if I drank booze and if I was seen having sex with anyone or leaving with whoever. He
wanted to know my every move, so, I would be as bad as possible and he loved it!"*
Miestorm also sent me some of his own personal [**>> photo's from inside Studio 54 <<**](javascript: openWindowSized('studio54-pics.shtml',700,850)) .
The party went on great for the club and people were saying this was the best thing that had ever happened
and this would last forever... But as everything else, the success story of Studio 54 also had an end.
Jack Dushey had tried to convince Steve & Ian to give up the black economy of the Skim and go legit, but they
just wouldn't listen. Then in 1979 Donald Moon, a former employee who had been "not very tactfully fired"
by Steve, used his knowledge of the black money to turn the Feds and IRS on the owners.
In late spring 1979 Jack approached the feds and pleaded guilty to one single point of tax evasion and in
the end of June Steve and Ian were charged with skimming $2.5 million.
In December of 1979 the IRS arrested Steve and Ian for withholding of taxes and the club was also said to
be a central for cocaine distribution. The two owners never thought they would have to go to jail, but they
were sentenced to three and a half years in prison and in February 1, 1980 they were in behind bars.
After having informed on and turned in some of their ex-partners and competitors they got their time cut
down to 13 months.
The clubs liquor license expired in February 28, 1980 - just 28 days after Steve & Ian went to jail and a
new license would take 18 months to get. This was devastating to a club like 54: No booze = No guests. And
papers claimed it was **Sylvester Stallone** who had the last legal drink. Then in March, just days
after the license expired the club died and was closed down.
The club was then sold to **Mark Fleischman** who re-opened Studio 54 in September 15, 1981. Steve
and Ian were out of jail and were even working in the club again for a while as consultants, as part of the
deal. But the club never could revive its former popularity and lots of the famous people seen in the studio
before Steve and Ian got busted, were never seen there again. Mark run the place for some four years and
in 1986 he decided to close down the Studio 54.
Steve and Ian had left long before this to get into the hotel business and they where also involved as
consultants in some nightclub projects. But they never got the same attention as they got at the "original"
Studio 54. And in July 1989 Steve died of AIDS related complications.
Ian Schrager is still active in the hotel business and owns a chain of 5 star Hotels over the world, called
**Ian Schrager Hotels**. Among these hotels are the famous **Clift Hotel** in San Francisco, **the
Paramount Hotel** in New York, **Miramar** in Santa Barbara and **The Sanderson** in London.
[BUY - Fabulous - A photographic diary of Studio 54 by Bobby Miller](mailto:troubleblonde@comcast.net?subject=I want to buy Fabulous!)
Photographer **Bobby Miller** entered the '54' in its first days and stayed there over the next couple of years,
always with his camera ready, through which he catched all these *Fabulous!* photos of the people frequenting
the club. His legendary pic's have been seen in lots of magazines all over the world and in this book he has put
some of them together, with his own notes and memories attached to them.
This book is an excellent timeline and it catches the magic of the club's first years and the photos portraits famous
people like **Christopher Reeve** [actor], **Dustin Hoffman** [actor], **Grace Jones** [model & artist],
**Elton John** [artist], **Jerry Hall** [model], **Yul Brynner** [actor], **Mikhail Baryshnikov** [dancer],
**Gloria Swanson** [actor], **Martha Graham** [dancer/choreographer], **Eartha Kitt** [artist], **Olivia
Newton-John** [artist actor], **Bette Midler** [artist] and of course "inventories" like **Steve Rubell**,
**Andy Warhol**, **Liza Minelli**, **Disco Sally** and **Truman Capote**. But there are LOTS of other famous
persons as well in the authors *Fabulous!* book.
Here's your chance to get hold of Bobby's out-of-print book - **Fabulous!** - *A photographic diary of
**Studio 54*** [St. Martin's Press]. Bobby himself is offering the viewers of **Disco-Disco.com**
brand new and signed copies of his wonderful and hard-to-find hardcover book for only $190 + shipping. Note that used
signed copies of this book go for up to $250 on e-bay.
Buy your signed copy of **Fabulous!**[>> **Click here!** <<](mailto:troubleblonde@comcast.net?subject=I want to buy Fabulous!).
What happened to the club? Well it actually became a strip club for a couple of years. But in October, 1994
it was re-reopened as Studio 54 again. For this re-opening the new owners managed to bring in old Disco
stars like [**Gloria Gaynor**](../artists/gloria.shtml), **Vicki Sue Robinson**
and **Sister Sledge** to perform. The new opening was a success and the club runs for some
months when the owner suddenly took all the money and left. And the club went into bankruptcy in the beginning
of 1995.
It was said the place would be turned into something else, but the club was still there and it was used for
special occasions. I know for example that people like **Gloria Estefan** made special
performances in the club.
I was in New York in October, 1998 and I just had to walk by this famous address and at that time
- the 54 logo sign was still there above the entrance. But just some weeks later the sign was torn down and
was replaced by a sign for the 'Cabaret' musical that was playing there for some years.
[Last days of Disco](../disco/cds.shtml#LDOD)
Since talking 'bout Studio 54... There were 2 movie releases out in 1998 trying to capture the magic and
the great music of this famous Discotheque. One was a film called **The Last Days of Disco** and
it was directed by **Whit Stillman** (director of "Metropolitan" and "Barcelona"). The story is about
**Studio 54** in the late 1970's/early 1980's and the people who hang there. The soundtrack, however, is
the star of the film: featured prominently are *"Good Times"*, *"Le Freak"* and *"Everybody Dance"*
by **Chic**, as well as *"I'm Coming Out"* by **Diana Ross** and *"He's The Greatest Dancer"*
by **Sister Sledge** and some other classic Disco songs. **The film is a veritable
[Nile & Bernard](../tributes/chic.shtml) tribute in itself!**
[54 - the CD](../disco/cds.shtml#54)
The other movie was just called **"54"** and was the life story of the late Steve Rubell with most attention
on Studio 54. Steve was played by **Mike Meyers** (Waynes World) and the ever so great **Neve Campbell**
also had a leading role in the picture together with **Lauren Hutton**. Some of the scenes for the movie were
actually shot at the original Studio 54, that were some exterior and lobby scenes. With this movie it came no
less than 2 albums with great music, of course there was one **Chic** track - *"Dance, dance, dance"*.
Other of the great Disco songs on the albums were; *"Keep on dancin'"* (**Gary's Gang**), *"the Boss"*
(**Diana Ross**), *"Vertigo/Relight my fire"* (**Dan Hartman** R.I.P), *"Move on up"*
(**Destination**), *"I got my mind made up"* (**Instant Funk**), *"Don't leave me this way"*
(**Thelma Houston**), *"Come to me"* (**France Joli**), *"Take your time - do it right"*
(**S.O.S Band**), *"Spank"* (**Jimmy "Bo" Horne**) and *"Heart of glass"* (**Blondie**).
With the **"54"** album came also the new hit *"If you could read my mind"* by **Stars on 54**. A
constellation of **Ultra Naté**, **Amber** and **Jocelyn Enriquez**. This is actually a cover of an
old **Viola Wills** song with the same name.
Many people has also asked about an instrumental song that is played about 7 minutes into the movie, just when Shane
enters the club for the first time. The song is *"the Break"* by **Kat-Mandu** and it's not featured in any
of the two soundtrack CD's.
Pet Shop Boys - New York City Boy
VERY inspired by the **"54"** movie was **Pet Shop Boys**' video to their hit song *"New York City Boy"*,
released in October 1999. The storyline is similar to the movie - This guy dreams about going to Manhattan and to the
Studio 54. Finally he gets there and everyone is there, Bianca Jagger on her white horse, Andy Warhol - yes, everything
you could expect. It's a great video. The song itself is (according to the guys) a tribute to **Village People**
and it is really breathing classic DISCO. The "Boys" have been working with famous remixer **David Morales** and
together they have made a GREAT song!
It's not only the Pet Shop Boys who has been inspired by this legendary club. Even **Madonna**'s 2006 world tour -
the *Confessions Tour* will be a celebration to the club and the Disco lifestyle. It has been announced that
Madonna will be recreating hedonistic scenes from the notorious nightclub in a stage set for her tour along with loads
of Disco mirror balls. '54' will make a great background set for her Disco influenced music from her most danceable
release for a long time, the **Confessions on a Dance floor** album.
Madonna first performed in the legendary club in 1983 in a party for the Italian fashion house, **Fiorucci**. At that
time she remarked to actor **David Alan Grier**: "You and me are going to be big stars, baby,
and leave these other suckers in the dust." Indeed she did, and it seems the wheel has come full circle when
she now, 20+ years later, return to Studio 54 where part of her success started.
[Another Studio 54 DJ mix](../sounds/studio54-2.ra)
Even though Steve Rubell and Ian Schrager's empire only lasted for 33 months it was an orgy in music, money,
glamour and drugs. There were endless number of unforgettable parties and all the "right" people were there.
**Studio 54** is an Icon of the Disco era and it was without any doubt as important to Disco as the engine
is to a car, without it - it wouldn't run. The club was the Center of the Disco Universe, along with some other
clubs and of course all the great artists and labels whom the club would have been nothing without. But without
clubs like Studio 54 the whole Disco era wouldn't probably have been as huge as it really was. The suites of this
great era still influence the music and nightlife today. The Disco era set the standards for the clublife and
music today.
Many people have wanted to open up the club again and in May/June of 2001 part of the legendary club was re-opened
as **Upstairs at Studio 54**.
It's the former balcony which, back in the clubs later days, were strictly celeb's only that has been turned into
a club again. Saturdays at the club has been told to be among the best places in town.
Again, it's not the complete legendary club that's re-opened and the space has been used for conferences and special
appearances as well as a theatre. The Broadway success **Cabaret** was played there for a long time and in April
2005 **A Streetcar Named Desire** was set up in the former club.
This was the story about THE most famous club of all times...
Studio 54
the Center of the Disco Universe!
|
Discuss Studio 54 in the [**FORUM**](http://www.disco-disco.com/forum/viewforum.php?f=11)
View Studio 54 [**photos and invites**](javascript: openWindowSized('studio54-pics.shtml',700,850)).
© Discoguy ([discoguy@disco-disco.com](mailto:discoguy@disco-disco.com)) 1999-2021.
All rights reserved.
No part of these pages may be reproduced or published without the prior written permission of the author.
**BIG THANKS**
to Paolo & Miestorm
for input, memories and for Miestorm's photos !!!
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Hello from Wade Hatler, my wife Amalia Gómez Sancha and our daughter Selena Hatler Sancha. We're
glad you stopped by. Welcome to Our World! Part of the page is bilingual (English and Spanish).
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Hola de
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Solo parte de esta pagina tiene texto en español, y el texto es muy malo por que yo he estudiado español solo
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<p lang="EN">
If you're someone we met on our trip around the world,
<span lang="en-us">
read the story
</span>
<a href="VisionQuest/index.html">Wade's Vision Quest Journal</a>. If you just want to know about
<span lang="en-us">
our
</span>
wacky
<span lang="en-us">
bikes
</span>
, jump into the middle of the journal at the <a href="VisionQuest/VQ_Bike.htm">Recumbent Bike</a> page.
<span lang="en-us">
Sorry, but both are English only.
</span>
</p>
<p lang="ES">
Si tú es una persona nos conocido en nuestro viaja ronda del mundo, lee la historia a Wade's <a href="VisionQuest/index.html">Vision
Quest Journal</a>. Si tú solo querido saber son nuestras loca bicicletas, vamos a medio de pagina a el <a href="VisionQuest/VQ_Bike.htm">Recumbent
Bike</a> pagina. Perdone, ambos es solo en Inglés.
</p>
<p lang="EN">
Send comments
<span lang="en-us">
or
</span>
suggestions to
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Wade & Amalia's Home Page
# Wade
,
Amalia
& Selena's
Home Page
[![Wade & Amalia At A Rest Stop in Canada in 2003](21-0600%20America%20Michigan%20UP%20&%20Wisconsin%20Wade%20Cuca.jpg)](VisionQuest/index.html)
[![Wade Cycling Near Mi Lai in Vietnam In 2001](06-A033%20Vietnam%20Nha%20Trang%20Wade%20-%20Progress%20Report.jpg)](VisionQuest/index.html)
---
LingoToolbar('Left')
Hello from Wade Hatler, my wife Amalia Gómez Sancha and our daughter Selena Hatler Sancha. We're
glad you stopped by. Welcome to Our World! Part of the page is bilingual (English and Spanish).
The Spanish isn't very good because I've only studied for 2 months, but it will improve. On
Bilingual pages, the Spanish text is blue, and you can change the language with a control at the top.
Hola de
parte de
Wade Hatler, mi mujer Amalia Gómez Sancha y
su
hija Selena Hatler Sancha.
Nosotros feliz tú has visitado. ¡Bienvenido a
nuestro
mundo!
Solo parte de esta pagina tiene texto en español, y el texto es muy malo por que yo he estudiado español solo
durante 2 meses. Las paginas con texto de español tienen control encima de pagina para seleccionar
idiomas. Cuando idioma es bilingüe, el texto de español es azul.
If you're someone we met on our trip around the world,
read the story
[Wade's Vision Quest Journal](VisionQuest/index.html). If you just want to know about
our
wacky
bikes
, jump into the middle of the journal at the [Recumbent Bike](VisionQuest/VQ_Bike.htm) page.
Sorry, but both are English only.
Si tú es una persona nos conocido en nuestro viaja ronda del mundo, lee la historia a Wade's [Vision
Quest Journal](VisionQuest/index.html). Si tú solo querido saber son nuestras loca bicicletas, vamos a medio de pagina a el [Recumbent
Bike](VisionQuest/VQ_Bike.htm) pagina. Perdone, ambos es solo en Inglés.
Send comments
or
suggestions to
document.write(String.fromCharCode(30 \* 2, 105, 62, 60, 97) + String.fromCharCode(16 \* 2, 104, 114, 101, 102, 61, 34, 109, 97, 105, 108, 116, 111, 58, 87, 97, 100, 101, 72, 97, 116, 108, 101, 114, 60+8-4, 119, 97, 100, 101, 109, 97, 110, 46, 99, 111, 109, 34, 62, 87, 97, 100, 101, 72, 97, 116, 108, 101, 114, 128/2, 119, 97, 100, 101, 109, 97, 110, 46, 99, 111, 109, 60, 47, 97, 62, 60, 47, 105, 62, 46))
Escrito comentas o sugerencia a
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---
RestoreLingo();
| http://www.wademan.com/ |
<html>
<title>Furby Autopsy</title>
<META NAME="keywords" CONTENT="furby, electronics, toys, electronic toys, hacking">
<META NAME="description" CONTENT="Furby Autopsy">
<BODY TEXT="#000000" LINK="#B41921" ALINK="#107D0D" BGCOLOR="#F5C22A">
<center>
<table border=0 height=400 width=500 cellpadding=4 cellspacing=2>
<tr>
<td valign=top colspan=2><center>
<a href="butnbar.gif.map"><img src="butnbar.gif" height=186 width=94 border=0 usemap="#butnbar.gif.map" ismap></a><MAP NAME="butnbar.gif.map"><AREA SHAPE=rect COORDS="0,0,93,31" HREF="auto1.html"><AREA SHAPE=rect COORDS="0,31,94,63" HREF="guts.html"><AREA SHAPE=rect COORDS="0,63,93,93" HREF="cause.html"><AREA SHAPE=rect COORDS="0,93,93,125" HREF="hacking.html"><AREA SHAPE=rect COORDS="0,125,94,157" HREF="http://www.phobe.com/furby/index.html"><AREA SHAPE=rect COORDS="0,157,94,186" HREF="mailto: furby@phobe.com"></MAP><img src="furbytag.jpg" alt="furby autopsy" height=186 width=322>
</center>
</td>
</tr>
<td valign=top>
<br><img src="dontstealpix.jpg" alt="skinned furby!" height=287 width=151 align=right>
<p>
<p>Questions? Check out the <a href="faq2.html"> FAQ</a>.<P>
Don't miss <a href="onice.html">Toh-Loo-Ka on ice</a>. Yes, he may be dead, but don't worry about his little corpse -- he's a furbsicle!<P>
After having <b>Toh-Loo-Ka</b> for about three days, and then leaving him "sleeping" for another day or two, his batteries ran out. After replacing the batteries, he no longer acted like the happy furby we'd be accustomed to being mildly annoyed by. He would get stuck with his eyes half open and emit a mild buzzing noise. Hitting reset wouldn't help, but sometimes helping move his eyes would unjam him, but he would quickly get stuck again.
<P>
When we first got him, he sat buzzing for about ten minutes, then finally woke up. (We initially attributed it to some sort of "boot up" or initialization procedure.) Periodically during his first day, he would freeze up, and remain unresponsive for about five or ten minutes. This behavior stopped after the first day and he was a healthy furby for a couple days.
<P>
When he started jamming again, we left him alone wondering if he would recover like he did on his first day. Unfortunately, we started smelling something electrical overheating after a few minutes of buzzing, so we disconnected his batteries.
<P>
Dozens of experiments with trying to unjam and reset and reboot him were unable to restore him to healthy operation. <b>Toh-Loo-Ka</b> was definitely a terminally ill Furby. So we did what any bereaved furby owner would do...we cut him up and took pictures.
<P><img src="dontstealpix2.gif" height=183 width=173 alt="dead furby outline" align=left>
We've also included step-by step instructions on how to perform your own Furby Autopsy (though doing so will most likely void its warranty), and details of what we found inside and how it all works (or doesn't). <P>
<b>Note</b>: Please don't ask us where you can purchase a Furby of your own...we have no idea. Ours was bought for scientific purposes only, and frankly, we find him much more amusing dead than he was alive.
</tr>
</table>
<br>
</center>
<center>
<FONT SIZE="2">
| <a href="auto1.html">autopsy how-to</a> | | <a href="guts.html">guts & stuff</a> | | <a href="cause.html">official cause of death</a> | | <a href="hacking.html">hacking</a> | | <a href="faq2.html">FAQ</a> | | <a href="mailto: furby@phobe.com">contact the coroner</a> | <br><br>
<a href="http://www.phobe.com">back to phobe.com</a><br>
<FONT SIZE="1">copyright 1998 phobe.com. <br>Taking your Furby apart probably voids its warranty: we take no responsibility for broken Furbies.<br>
Furbies are the intellectual property of <a href="http://www.furby.com">Tiger Electronics</a>.</FONT><br><br>
<A HREF="http://www.usatoday.com/life/cyber/cyber1.htm"><IMG
SRC="http://www.usatoday.com/life/cyber/usatstat.gif" BORDER=0 ALIGN="BOTTOM"
ALT="USA TODAY AWARD"></A>
</center>
|
Furby Autopsy
| |
| --- |
|
furby autopsy
|
skinned furby!
Questions? Check out the [FAQ](faq2.html).
Don't miss [Toh-Loo-Ka on ice](onice.html). Yes, he may be dead, but don't worry about his little corpse -- he's a furbsicle!
After having **Toh-Loo-Ka** for about three days, and then leaving him "sleeping" for another day or two, his batteries ran out. After replacing the batteries, he no longer acted like the happy furby we'd be accustomed to being mildly annoyed by. He would get stuck with his eyes half open and emit a mild buzzing noise. Hitting reset wouldn't help, but sometimes helping move his eyes would unjam him, but he would quickly get stuck again.
When we first got him, he sat buzzing for about ten minutes, then finally woke up. (We initially attributed it to some sort of "boot up" or initialization procedure.) Periodically during his first day, he would freeze up, and remain unresponsive for about five or ten minutes. This behavior stopped after the first day and he was a healthy furby for a couple days.
When he started jamming again, we left him alone wondering if he would recover like he did on his first day. Unfortunately, we started smelling something electrical overheating after a few minutes of buzzing, so we disconnected his batteries.
Dozens of experiments with trying to unjam and reset and reboot him were unable to restore him to healthy operation. **Toh-Loo-Ka** was definitely a terminally ill Furby. So we did what any bereaved furby owner would do...we cut him up and took pictures.
dead furby outline
We've also included step-by step instructions on how to perform your own Furby Autopsy (though doing so will most likely void its warranty), and details of what we found inside and how it all works (or doesn't).
**Note**: Please don't ask us where you can purchase a Furby of your own...we have no idea. Ours was bought for scientific purposes only, and frankly, we find him much more amusing dead than he was alive.
|
| [autopsy how-to](auto1.html) | | [guts & stuff](guts.html) | | [official cause of death](cause.html) | | [hacking](hacking.html) | | [FAQ](faq2.html) | | [contact the coroner](mailto: furby@phobe.com) |
[back to phobe.com](http://www.phobe.com)
copyright 1998 phobe.com.
Taking your Furby apart probably voids its warranty: we take no responsibility for broken Furbies.
Furbies are the intellectual property of [Tiger Electronics](http://www.furby.com).
[![USA TODAY AWARD](http://www.usatoday.com/life/cyber/usatstat.gif)](http://www.usatoday.com/life/cyber/cyber1.htm)
| http://phobe.com/furby/ |
<!DOCTYPE HTML PUBLIC "-//IETF//DTD HTML 2.0//EN">
<html><head>
<title>406 Not Acceptable</title>
</head><body>
<h1>Not Acceptable</h1>
<p>An appropriate representation of the requested resource could not be found on this server.</p>
<p>Additionally, a 406 Not Acceptable
error was encountered while trying to use an ErrorDocument to handle the request.</p>
</body></html>
|
406 Not Acceptable
# Not Acceptable
An appropriate representation of the requested resource could not be found on this server.
Additionally, a 406 Not Acceptable
error was encountered while trying to use an ErrorDocument to handle the request.
| http://www.deepwoods.org/ |
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name="image18"><br><img src="/contents/public/orange-dot.gif" width="700" height="1"></td></tr></table></center><br><img src="/public/nothing.gif" height="6" width="1"><table width="100%" cellspacing="0" cellpadding="0" border="0"><tr><td width="58%" valign="top"><font face="Arial,Microsoft Sans Serif" size="4"><b>The Experiment</b></font><br><img src="/public/linecolor.gif" width="430" height="2" style="width: 100%; height: 2px;"><br><img src="/public/nothing.gif" height="4" width="1"><br><a href="/category?id=cce3df80f07d36b56db4376a4802d6c2"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Videos</b></font></a><font size="-1"> | </font><a href="/category?id=2b597a0492c5e85492ab16ad3cffd30b"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Vintage Web</b></font></a><font size="-1"> | </font><a href="/category?id=414a8b302155e07fca3e1ddfeda36f43"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Retro Computing</b></font></a><font size="-1"> | </font><a href="/category?id=a269083067d8803e9c77ad78cc947ce4"><font face="Arial,Microsoft Sans Serif" size="-1"><b>3D Printing</b></font></a><font size="-1"> | </font><a href="/category?id=e33e2bd11cf9e8857c9153e3a62fddef"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Off-Topic</b></font></a><font size="-1"> | </font><a href="/category?id=554d7f8fe5d6c4900d289209bdd739ac"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Opinion</b></font></a><font size="-1"> | </font><a href="/category?id=56c5f555b27978391ee26e2fb95c2482"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Computing</b></font></a><font size="-1"> | </font><a href="/category?id=967ef2eb34634ba418db94dab610ba6f"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Gaming</b></font></a><font size="-1"> | </font><a href="/category?id=113422dfd86463d669e94c07cf61e0dc"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Consoles</b></font></a><font size="-1"> | </font><a href="/category?id=0fb795515254822fa904e3ad8d0c9e88"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Retro Gaming</b></font></a><font size="-1"> | </font><a href="/category?id=31c13f47ad87dd7baa2d558a91e0fbb9"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Design</b></font></a><font size="-1"> | </font><a href="/category?id=539e0f104514e3b588520557ba5b2630"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Woodworking</b></font></a><font size="-1"> | </font><a href="/category?id=5bcfa80d33c4dd9b6f5bfa1f4f1f0445"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Portables</b></font></a><font size="-1"> | </font><a href="/category?id=18d6769919266cd0bd6cd78aa405d5d0"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Music</b></font></a><font size="-1"> | </font><a href="/category?id=532c28d5412dd75bf975fb951c740a30"><font face="Arial,Microsoft Sans Serif" size="-1"><b>Mobile</b></font></a><br><img src="/public/nothing.gif" height="4" width="1"><br><img src="/public/linecolor.gif" width="430" height="2" style="width: 100%; height: 2px;"><p><a href="/post/15-06-2023-relive-yahoo-directories-with-oldavista"><img src="/contents/posts/15-06-2023-relive-yahoo-directories-with-oldavista/img.jpg" alt="Relive the Glory Days of Yahoo with Old'aVista Directories" width="80" border="0" align="left"></a><a href="/post/15-06-2023-relive-yahoo-directories-with-oldavista"><font ><b>Relive the Glory Days of Yahoo with Old'aVista Directories</b></font></a> - <font >Revisit the internet's past with Old'aVista Directories! This unique tool revives the Yahoo directories from the late '90s and early 2000s, offering a genuine trip down memory lane. Created using Yahoo Directories data scraped from the Internet Archive fro</font><br clear="ALL"></p><p><a href="/post/24-05-2023-interview-tiny-486-toms-hardware-the-pi-cast"><img src="/contents/posts/24-05-2023-interview-tiny-486-toms-hardware-the-pi-cast/img.jpg" alt="The Pi Cast Guest Appearance About The Tiny 486" width="80" border="0" align="right"></a><a href="/post/24-05-2023-interview-tiny-486-toms-hardware-the-pi-cast"><font ><b>The Pi Cast Guest Appearance About The Tiny 486</b></font></a> - <font >I participated on Tom's Hardware's The Pi Cast podcast to talk about my tiny 486 build, make sure to check it out!</font><br clear="ALL"></p><p><a href="/post/16-04-2023-tiniest-486-computer"><img src="/contents/posts/16-04-2023-tiniest-486-computer/img.jpg" alt="The Tiniest 486 Computer: I Built It From Scratch!" width="80" border="0" align="left"></a><a href="/post/16-04-2023-tiniest-486-computer"><font ><b>The Tiniest 486 Computer: I Built It From Scratch!</b></font></a> - <font >It took me over two years, but it's finaly here! My tiny 486 computer with a real Intel 486 DX4 inside!</font><br clear="ALL"></p><p><a href="/post/14-04-2023-spotify-legalized-napster"><img src="/contents/posts/14-04-2023-spotify-legalized-napster/spotify-napster.jpg" alt="Spotify - Just a Legalized Napster?" width="80" border="0" align="right"></a><a href="/post/14-04-2023-spotify-legalized-napster"><font ><b>Spotify - Just a Legalized Napster?</b></font></a> - <font >Spotify is not much different from Napster in my opinion, the only difference is who wins and who loses and artists lose with both.</font><br clear="ALL"></p><p><a href="/post/30-03-2023-smart-home-tech-sucks"><img src="/contents/posts/30-03-2023-smart-home-tech-sucks/img.jpg" alt="Smart Home Tech Sucks" width="80" border="0" align="left"></a><a href="/post/30-03-2023-smart-home-tech-sucks"><font ><b>Smart Home Tech Sucks</b></font></a> - <font >Let's be honest, smart home tech kinda sucks and in this post I'll discuss my experience with it and why I think that.</font><br clear="ALL"></p><p><a href="/post/05-09-2022-goodbye-pitica"><img src="/contents/posts/05-09-2022-goodbye-pitica/img.jpg" alt="Goodbye, Pitica." width="80" border="0" align="right"></a><a href="/post/05-09-2022-goodbye-pitica"><font ><b>Goodbye, Pitica.</b></font></a> - <font >...</font><br clear="ALL"></p><p><a href="/post/30-06-2022-goodbye-stella"><img src="/contents/posts/30-06-2022-goodbye-stella/img.jpg" alt="Goodbye, Stella." width="80" border="0" align="left"></a><a href="/post/30-06-2022-goodbye-stella"><font ><b>Goodbye, Stella.</b></font></a> - <font >...</font><br clear="ALL"></p><p><a href="/post/17-03-2022-unraid-nas"><img src="/contents/posts/17-03-2022-unraid-nas/img.jpg" alt="I Ran Out Of Space, Let's Build An UNRAID NAS!" width="80" border="0" align="right"></a><a href="/post/17-03-2022-unraid-nas"><font ><b>I Ran Out Of Space, Let's Build An UNRAID NAS!</b></font></a> - <font >I sadly ran out of spaced on my Synology NAS, so let's go through building an UNRAID server to replace it</font><br clear="ALL"></p><a href="/posts?page=1"><img src="/public/more_md_wht.gif" border="0"></a></td><td width="4%"><img src="/public/nothing.gif" width="4" height="1"></td><td width="38%" valign="top"><img src="/public/anibar.gif" width="320" height="1" style="width: 100%; height: 1px;"><br><img src="/public/welcome.gif"><br><img src="/public/anibar.gif" width="320" height="1" style="width: 100%; height: 1px;"><p><p><img src="/contents/public/avatar.jpg" align="left"> Hello! My name is Eric and this is my little corner of the Internet, a place where where you can check out many cool projects related to retro computing, retro gaming, coding, music, some other random tech stuff I'm working on as well as other things related to my life.</p><p>This website features a more diverse set of projects but I also run the channel <a href="https://www.youtube.com/user/EricMackrodt?sub_confirmation=1" target="_blank">The Eric Experiment</a> on YouTube, which is more focused on retro gaming and retro computing.</p><p>If you like those sorts of subjects, make sure to follow this website or subscribe to the <a href="https://www.youtube.com/user/EricMackrodt?sub_confirmation=1" target="_blank">Youtube channel</a>!</p><p>This website is Retro First, which means that it's built for Old Browsers, but it loads more features as you move to more modern browsers. It's not mobile friendly though because if you follow me, you probably browse the web on a computer.</p></p><img src="/public/anibar.gif" width="320" height="1" style="width: 100%; height: 1px;"><br><p><!-- Start Old'aVista Button Code --><a href="http://www.oldavista.com/" rel="embed-button" title="Old'aVista: The most powerful guide to the OLD internet!" target="_blank"><img src="//www.oldavista.com/public/button.gif" width="88" height="31" border="0"></a><!-- End Old'aVista Button Code --><a href="/windows3x/essentialsoftware#netscapecommunicator407"><img src="/public/netscap4.gif" alt="Compatible with Netscape" border="0"></a><a href="/windows3x/essentialsoftware#internetexplorer501"><img src="/public/ie.gif" width="88" height="31" alt="Compatible with IE" border="0"></a><br><img src="/public/table-layout.gif" border="0"><img src="/public/800x600.gif" border="0"><img src="/public/frontpg.gif" border="0"><br><a href="/windows3x/essentialsoftware#mirc591"><img src="/public/mircban.gif" border="0"></a><a href="http://www.theoldnet.com/#frombadge" title="Are you tired of this new Internet yet? Time to Get TheOldNet!" target="_blank"><img src="//theoldnet.com/images/theoldnetanimblur2.gif" width="88" height="31" border=0></a><a href="HTTP://ucanet.net"><img src="/public/ucabtn.gif" border="0"></a></p><img src="/public/raptor_walk_md_clr.gif" alt="raptor"></td></tr></table><center><img src="/public/flamingline.gif"></center><br><table width="100%" cellspacing="0" cellpadding="0" border="0"><tr><td width="48%" valign="top"><table border="0" cellspacing="0" cellpadding="0"><tr><td><img src="/public/tag.gif"></td><td><img src="/public/nothing.gif" height="4" width="1"></td><td valign="middle"><font face="Arial,Microsoft Sans Serif" size="3"><b>Tags</b></font></td></tr></table><img src="/public/linecolor.gif" width="100%" height="2"><br><img src="/public/nothing.gif" height="4" width="1"><a href='/tag?id=414a8b302155e07fca3e1ddfeda36f43'>retro computing (12)</a> <a href='/tag?id=0fb795515254822fa904e3ad8d0c9e88'>retro gaming (7)</a> <a href='/tag?id=e33e2bd11cf9e8857c9153e3a62fddef'>off-topic (5)</a> <a href='/tag?id=967ef2eb34634ba418db94dab610ba6f'>gaming (5)</a> <a href='/tag?id=18d6769919266cd0bd6cd78aa405d5d0'>music (5)</a> <a href='/tag?id=6e59126599d56c64185acb1f12671959'>silly (4)</a> <a href='/tag?id=5c4896e9c83830181d5cf6625319ecc3'>windows 95 (4)</a> <a href='/tag?id=56c5f555b27978391ee26e2fb95c2482'>computing (4)</a> <a href='/tag?id=d3356450c74bf722fae96f8a916b5333'>geocities (3)</a> <a href='/tag?id=c3581516868fb3b71746931cac66390e'>internet (3)</a> <a href='/tag?id=bb229426f28a007aba951bc8f0a46d39'>windows 3.11 (3)</a> <a href='/tag?id=b618a1516e37844beddd72a162970289'>netscape (3)</a> <a href='/tag?id=b4aa2b48dbea8988e09addd46b4cbf38'>voodoo (3)</a> <a href='/tag?id=a1ed33ed66835f0428a1281959a9c05f'>web 1.0 (3)</a> <a href='/tag?id=98e1f108b5e78847dec7fff9ca486576'>lemmings (3)</a> <a href='/tag?id=788783fab296aac49dfdd4db3fd4b54f'>3dfx (3)</a> <a href='/tag?id=5f532a3fc4f1ea403f37070f59a7a53a'>microsoft (3)</a> <a href='/tag?id=4e5bbaeafc82ab7aa1385bea8ef5d30a'>intel (3)</a> <a href='/tag?id=3ca14c518d1bf901acc339e7c9cd6d7f'>hardware (3)</a> <a href='/tag?id=ed6683fd03d8695792839f01fab02c21'>lucasarts (2)</a> <a href='/tag?id=d732f0ceca31d7b12e7ddfe49513fb2f'>tiny computer (2)</a> <a href='/tag?id=d5c64e2a7aad2da98e9f065c8e88882d'>tiny retro computer (2)</a> <a href='/tag?id=c0eded533376e18c065a9502e9b43e8c'>retro software (2)</a> <a href='/tag?id=bf6b5623d2e2dc39385e141a4425eafb'>playstation 5 (2)</a> <a href='/tag?id=b78e5a00e054de81f31bdb18030d73f0'>intel 486 dx4 100 (2)</a> <a href='/tag?id=b672957176955d4d502c1b3d0a4731fa'>voodoo 5 5500 (2)</a> <a href='/tag?id=ab3e32cd6cb83d3f7a1252fb0cbbd843'>theoldnet (2)</a> <a href='/tag?id=aacd70cb40a2ffa30eba59c2c6e83da1'>ms-dos (2)</a> <a href='/tag?id=a269083067d8803e9c77ad78cc947ce4'>3d printing (2)</a> <a href='/tag?id=a141472065cc26e1ffce0a359ff3c733'>aol (2)</a> <a href='/tag?id=9ac3d9dfe434dd6aa006a1138e8915de'>mini retro computer (2)</a> <a href='/tag?id=823058d803ed8663477a7d34cbee556e'>miniature computer (2)</a> <a href='/tag?id=7e540aa619eb545a6659208c1b4f98b6'>windows xp (2)</a> <a href='/tag?id=7d04bbbe5494ae9d2f5a76aa1c00fa2f'>486 (2)</a> <a href='/tag?id=7a0bba91dfd96ea54a1b11a7a37e597f'>angelfire (2)</a> <a href='/tag?id=743119a0bdc200c33ae1f2ca2bb643ce'>3d printed computer (2)</a> <a href='/tag?id=6d0db9516aaa1e7adc05d5101679d773'>console repair (2)</a> <a href='/tag?id=6b3166c60489d7993f8d63b7d110b826'>intel 486dx4 (2)</a> <a href='/tag?id=69e7cfc22cbcf3606b139fea0e69f16e'>the dig (2)</a> <a href='/tag?id=5effba842bf55eb7ef3fe96302167166'>miniature retro computer (2)</a> <a href='/tag?id=458a2eb0daa8654a68c39ef768141728'>ps5 (2)</a> <a href='/tag?id=436129eb47513a80ab2c013e1ecba481'>internet explorer (2)</a> <a href='/tag?id=426293bc9c5760a57868d49d986ca668'>skyroads (2)</a> <a href='/tag?id=421b47ffd946ca083b65cd668c6b17e6'>video (2)</a> <a href='/tag?id=39aabf45af9efb56cb55b118e297e412'>xoom (2)</a> <a href='/tag?id=31c13f47ad87dd7baa2d558a91e0fbb9'>design (2)</a> <a href='/tag?id=2852f27d3d8bb0727eaf9f21270e0584'>mini computer (2)</a> <a href='/tag?id=277f2a7ecb7cfcd264aeb2067fb46df8'>alexa (2)</a> <a href='/tag?id=205a357ae136200fb5b2829895b50535'>youtube shorts (2)</a> <a href='/tag?id=12f0a8c7b1f43f325fabfd270cf25bf3'>comedy (2)</a> <a href='/tag?id=04980744f74f4ec36ad5a9d5fec8876f'>interview (2)</a></td><td width="4%"><img src="/public/nothing.gif" width="4" height="1"></td><td width="48%" valign="top"><table border="0" cellspacing="0" cellpadding="4" width="100%"><tr><td><table border="0" cellspacing="0" cellpadding="0"><tr><td><img src="/public/newspaper.gif"></td><td><img src="/public/nothing.gif" width="4" height="1"></td><td valign="middle"><font face="Arial,Microsoft Sans Serif" size="3"><b>Extra!</b></font></td></tr></table><img src="/public/linecolor.gif" width="100%" height="2"><br><img src="/public/nothing.gif" height="4" width="1"><br><table border="0" cellspacing="0" cellpadding="0"><tr><td valign="top"><img src="/public/nothing.gif" width="2" height="1"><img src="/public/animated_bullet_009.gif"> </td><td><font face="Courier New, Arial, Times New Roman" size="3" color="lime"><b>[30/08/2023]</b></font><font face="Times New Roman" size="3">Added new programs for download in the Windows 3.x Essential Software and the Software sections.</font></td></tr></table><img src="/public/nothing.gif" width="4" height="1"><table border="0" cellspacing="0" cellpadding="0"><tr><td valign="top"><img src="/public/nothing.gif" width="2" height="1"><img src="/public/animated_bullet_011.gif"> </td><td><font face="Courier New, Arial, Times New Roman" size="3" color="lime"><b>[07/08/2023]</b></font><font face="Times New Roman" size="3">Added a Guestbook to the website so you can leave messages, a Projects page with the ongoing projects I'm working on and I have finally added the <a href="http://ucanet.net" target="_blank">Ucanet</a> button to the home page.</font></td></tr></table><img src="/public/nothing.gif" width="4" height="1"><table border="0" cellspacing="0" cellpadding="0"><tr><td valign="top"><img src="/public/nothing.gif" width="2" height="1"><img src="/public/animated_bullet_014.gif"> </td><td><font face="Courier New, Arial, Times New Roman" size="3" color="lime"><b>[05/07/2023]</b></font><font face="Times New Roman" size="3">Huge design update, the website is now retro first and it doesn't have to switch between two different templates.</font></td></tr></table><img src="/public/nothing.gif" width="4" height="1"><table border="0" cellspacing="0" cellpadding="0"><tr><td valign="top"><img src="/public/nothing.gif" width="2" height="1"><img src="/public/animated_bullet_009.gif"> </td><td><font face="Courier New, Arial, Times New Roman" size="3" color="lime"><b>[16/09/2022]</b></font><font face="Times New Roman" size="3">Updated the website layout and several internal changes.</font></td></tr></table><img src="/public/nothing.gif" width="4" height="1"><table border="0" cellspacing="0" cellpadding="0"><tr><td valign="top"><img src="/public/nothing.gif" width="2" height="1"><img src="/public/animated_bullet_011.gif"> </td><td><font face="Courier New, Arial, Times New Roman" size="3" color="lime"><b>[06/07/2022]</b></font><font face="Times New Roman" size="3">A couple more sites added to Destinations.</font></td></tr></table><img src="/public/nothing.gif" width="4" height="1"></td></tr><tr><td align="center"></td></tr></table></td></tr></table><br><center><img src="/public/cat.gif"><br><img src="/public/geek_1.jpg" alt="geekring.net nvigation" usemap="#geekringmap" border="0"><map name="geekringmap"><area shape="rect" coords="9,28,111,53" alt="Previous geekring site" href="//geekring.net/site/208/previous"><area shape="rect" coords="248,28,350,53" alt="Random geekring site" href="//geekring.net/site/208/random"><area shape="rect" 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| **The Experiment**[**Videos**](/category?id=cce3df80f07d36b56db4376a4802d6c2) | [**Vintage Web**](/category?id=2b597a0492c5e85492ab16ad3cffd30b) | [**Retro Computing**](/category?id=414a8b302155e07fca3e1ddfeda36f43) | [**3D Printing**](/category?id=a269083067d8803e9c77ad78cc947ce4) | [**Off-Topic**](/category?id=e33e2bd11cf9e8857c9153e3a62fddef) | [**Opinion**](/category?id=554d7f8fe5d6c4900d289209bdd739ac) | [**Computing**](/category?id=56c5f555b27978391ee26e2fb95c2482) | [**Gaming**](/category?id=967ef2eb34634ba418db94dab610ba6f) | [**Consoles**](/category?id=113422dfd86463d669e94c07cf61e0dc) | [**Retro Gaming**](/category?id=0fb795515254822fa904e3ad8d0c9e88) | [**Design**](/category?id=31c13f47ad87dd7baa2d558a91e0fbb9) | [**Woodworking**](/category?id=539e0f104514e3b588520557ba5b2630) | [**Portables**](/category?id=5bcfa80d33c4dd9b6f5bfa1f4f1f0445) | [**Music**](/category?id=18d6769919266cd0bd6cd78aa405d5d0) | [**Mobile**](/category?id=532c28d5412dd75bf975fb951c740a30)[Relive the Glory Days of Yahoo with Old'aVista Directories](/post/15-06-2023-relive-yahoo-directories-with-oldavista)[**Relive the Glory Days of Yahoo with Old'aVista Directories**](/post/15-06-2023-relive-yahoo-directories-with-oldavista) - Revisit the internet's past with Old'aVista Directories! This unique tool revives the Yahoo directories from the late '90s and early 2000s, offering a genuine trip down memory lane. Created using Yahoo Directories data scraped from the Internet Archive fro[The Pi Cast Guest Appearance About The Tiny 486](/post/24-05-2023-interview-tiny-486-toms-hardware-the-pi-cast)[**The Pi Cast Guest Appearance About The Tiny 486**](/post/24-05-2023-interview-tiny-486-toms-hardware-the-pi-cast) - I participated on Tom's Hardware's The Pi Cast podcast to talk about my tiny 486 build, make sure to check it out![The Tiniest 486 Computer: I Built It From Scratch!](/post/16-04-2023-tiniest-486-computer)[**The Tiniest 486 Computer: I Built It From Scratch!**](/post/16-04-2023-tiniest-486-computer) - It took me over two years, but it's finaly here! My tiny 486 computer with a real Intel 486 DX4 inside![Spotify - Just a Legalized Napster?](/post/14-04-2023-spotify-legalized-napster)[**Spotify - Just a Legalized Napster?**](/post/14-04-2023-spotify-legalized-napster) - Spotify is not much different from Napster in my opinion, the only difference is who wins and who loses and artists lose with both.[Smart Home Tech Sucks](/post/30-03-2023-smart-home-tech-sucks)[**Smart Home Tech Sucks**](/post/30-03-2023-smart-home-tech-sucks) - Let's be honest, smart home tech kinda sucks and in this post I'll discuss my experience with it and why I think that.[Goodbye, Pitica.](/post/05-09-2022-goodbye-pitica)[**Goodbye, Pitica.**](/post/05-09-2022-goodbye-pitica) - ...[Goodbye, Stella.](/post/30-06-2022-goodbye-stella)[**Goodbye, Stella.**](/post/30-06-2022-goodbye-stella) - ...[I Ran Out Of Space, Let's Build An UNRAID NAS!](/post/17-03-2022-unraid-nas)[**I Ran Out Of Space, Let's Build An UNRAID NAS!**](/post/17-03-2022-unraid-nas) - I sadly ran out of spaced on my Synology NAS, so let's go through building an UNRAID server to replace it | | Hello! My name is Eric and this is my little corner of the Internet, a place where where you can check out many cool projects related to retro computing, retro gaming, coding, music, some other random tech stuff I'm working on as well as other things related to my life.This website features a more diverse set of projects but I also run the channel [The Eric Experiment](https://www.youtube.com/user/EricMackrodt?sub_confirmation=1) on YouTube, which is more focused on retro gaming and retro computing.If you like those sorts of subjects, make sure to follow this website or subscribe to the [Youtube channel](https://www.youtube.com/user/EricMackrodt?sub_confirmation=1)!This website is Retro First, which means that it's built for Old Browsers, but it loads more features as you move to more modern browsers. It's not mobile friendly though because if you follow me, you probably browse the web on a computer.[Compatible with Netscape](/windows3x/essentialsoftware#netscapecommunicator407)[Compatible with IE](/windows3x/essentialsoftware#internetexplorer501)raptor |
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| | | **Tags** |
[retro computing (12)](/tag?id=414a8b302155e07fca3e1ddfeda36f43) [retro gaming (7)](/tag?id=0fb795515254822fa904e3ad8d0c9e88) [off-topic (5)](/tag?id=e33e2bd11cf9e8857c9153e3a62fddef) [gaming (5)](/tag?id=967ef2eb34634ba418db94dab610ba6f) [music (5)](/tag?id=18d6769919266cd0bd6cd78aa405d5d0) [silly (4)](/tag?id=6e59126599d56c64185acb1f12671959) [windows 95 (4)](/tag?id=5c4896e9c83830181d5cf6625319ecc3) [computing (4)](/tag?id=56c5f555b27978391ee26e2fb95c2482) [geocities (3)](/tag?id=d3356450c74bf722fae96f8a916b5333) [internet (3)](/tag?id=c3581516868fb3b71746931cac66390e) [windows 3.11 (3)](/tag?id=bb229426f28a007aba951bc8f0a46d39) [netscape (3)](/tag?id=b618a1516e37844beddd72a162970289) [voodoo (3)](/tag?id=b4aa2b48dbea8988e09addd46b4cbf38) [web 1.0 (3)](/tag?id=a1ed33ed66835f0428a1281959a9c05f) [lemmings (3)](/tag?id=98e1f108b5e78847dec7fff9ca486576) [3dfx (3)](/tag?id=788783fab296aac49dfdd4db3fd4b54f) [microsoft (3)](/tag?id=5f532a3fc4f1ea403f37070f59a7a53a) [intel (3)](/tag?id=4e5bbaeafc82ab7aa1385bea8ef5d30a) [hardware (3)](/tag?id=3ca14c518d1bf901acc339e7c9cd6d7f) [lucasarts (2)](/tag?id=ed6683fd03d8695792839f01fab02c21) [tiny computer (2)](/tag?id=d732f0ceca31d7b12e7ddfe49513fb2f) [tiny retro computer (2)](/tag?id=d5c64e2a7aad2da98e9f065c8e88882d) [retro software (2)](/tag?id=c0eded533376e18c065a9502e9b43e8c) [playstation 5 (2)](/tag?id=bf6b5623d2e2dc39385e141a4425eafb) [intel 486 dx4 100 (2)](/tag?id=b78e5a00e054de81f31bdb18030d73f0) [voodoo 5 5500 (2)](/tag?id=b672957176955d4d502c1b3d0a4731fa) [theoldnet (2)](/tag?id=ab3e32cd6cb83d3f7a1252fb0cbbd843) [ms-dos (2)](/tag?id=aacd70cb40a2ffa30eba59c2c6e83da1) [3d printing (2)](/tag?id=a269083067d8803e9c77ad78cc947ce4) [aol (2)](/tag?id=a141472065cc26e1ffce0a359ff3c733) [mini retro computer (2)](/tag?id=9ac3d9dfe434dd6aa006a1138e8915de) [miniature computer (2)](/tag?id=823058d803ed8663477a7d34cbee556e) [windows xp (2)](/tag?id=7e540aa619eb545a6659208c1b4f98b6) [486 (2)](/tag?id=7d04bbbe5494ae9d2f5a76aa1c00fa2f) [angelfire (2)](/tag?id=7a0bba91dfd96ea54a1b11a7a37e597f) [3d printed computer (2)](/tag?id=743119a0bdc200c33ae1f2ca2bb643ce) [console repair (2)](/tag?id=6d0db9516aaa1e7adc05d5101679d773) [intel 486dx4 (2)](/tag?id=6b3166c60489d7993f8d63b7d110b826) [the dig (2)](/tag?id=69e7cfc22cbcf3606b139fea0e69f16e) [miniature retro computer (2)](/tag?id=5effba842bf55eb7ef3fe96302167166) [ps5 (2)](/tag?id=458a2eb0daa8654a68c39ef768141728) [internet explorer (2)](/tag?id=436129eb47513a80ab2c013e1ecba481) [skyroads (2)](/tag?id=426293bc9c5760a57868d49d986ca668) [video (2)](/tag?id=421b47ffd946ca083b65cd668c6b17e6) [xoom (2)](/tag?id=39aabf45af9efb56cb55b118e297e412) [design (2)](/tag?id=31c13f47ad87dd7baa2d558a91e0fbb9) [mini computer (2)](/tag?id=2852f27d3d8bb0727eaf9f21270e0584) [alexa (2)](/tag?id=277f2a7ecb7cfcd264aeb2067fb46df8) [youtube shorts (2)](/tag?id=205a357ae136200fb5b2829895b50535) [comedy (2)](/tag?id=12f0a8c7b1f43f325fabfd270cf25bf3) [interview (2)](/tag?id=04980744f74f4ec36ad5a9d5fec8876f) | |
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| | | **Extra!** |
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| | **[30/08/2023]**Added new programs for download in the Windows 3.x Essential Software and the Software sections. |
| | |
| --- | --- |
| | **[07/08/2023]**Added a Guestbook to the website so you can leave messages, a Projects page with the ongoing projects I'm working on and I have finally added the [Ucanet](http://ucanet.net) button to the home page. |
| | |
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| | **[05/07/2023]**Huge design update, the website is now retro first and it doesn't have to switch between two different templates. |
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| | **[16/09/2022]**Updated the website layout and several internal changes. |
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| | **[06/07/2022]**A couple more sites added to Destinations. |
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Honest,
and Real</span></font><br>
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<p><font size="+1">A</font>ttracting wildlife to your backyard is
a rewarding
and relaxing endeavor guaranteed to bring you many memorable
moments.
Its one of the few hobbies left that makes no distinctions between the
rich and the poor. In our hectic and materialistic world more
Americans
than ever before are turning back to nature and rediscovering the joy
and
balance that a connection with nature brings to the human soul. </p>
<font size="+1">T</font>here's something soothing about seeing
a hummingbird
or a colorful butterfly examining your garden. Perhaps the secret
of why nature seems to calm the human soul is really <i>no secret</i>
at
all. Maybe it simply has to do with some values we cherish and
easily
lose sight of in modern day society. In its simplest terms, there
is something pure, honest, real, and <i>down to earth</i> about seeing
wildlife out in our own backyards. <br>
<br>
--Rick<br>
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align="center" bgcolor="#ffffcc"> <b><font
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Wild Birds to Your Yard, and
Other Fun Things to Check Out</span><br>
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CD</a></font></font></td>
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<td align="left" valign="top">
<center><font face="Arial,Helvetica"><font size="-1"><a
href="http://my.pclink.com/%7Erlovgren/gifts1.htm">Gift
Ideas 1</a></font></font> <br>
<font face="Arial,Helvetica"><font size="-1">Pictures,
Mad Bluebird Coffee mug, and more!</font></font></center>
</td>
<td align="left" valign="top">
<center><font face="Arial,Helvetica"><font size="-1"><a
href="http://my.pclink.com/%7Erlovgren/gifts1a.htm">Gift
Ideas 1a</a></font></font> <br>
<font face="Arial,Helvetica"><font size="-1">Storage Cans, </font></font><font
face="Arial,Helvetica"><font size="-1">Ornaments, and more! <br>
</font></font></center>
</td>
<td align="left" valign="top">
<center><font face="Arial,Helvetica"><font size="-1"><a
href="http://my.pclink.com/%7Erlovgren/gifts2.htm">Gift
Ideas 2</a></font></font> <br>
<font face="Arial,Helvetica"><font size="-1">Nature Art Prints,
Candles, Solar Lighting, and more!<br>
</font></font></center>
</td>
<td style="vertical-align: top; text-align: center;"><font
face="Arial,Helvetica"><font size="-1"><a
href="http://my.pclink.com/%7Erlovgren/gifts3.htm">Gift
Ideas 3</a></font></font> <br>
<font face="Arial,Helvetica"><font size="-1">Weathervanes, Wind
chime, Tabletop fountain, etc.</font></font></td>
<td colspan="2" align="left" bgcolor="#ccffff" valign="top">
<center><font face="Arial,Helvetica"><font size="-1"><a
href="http://my.pclink.com/%7Erlovgren/hdgifts1.htm">Gift
Ideas 4</a></font></font> <br>
<font face="Arial,Helvetica"><font size="-1">Tabletop fountain,
Waterfalls, etc.<br>
<br>
</font></font></center>
</td>
</tr>
<tr>
<td colspan="5"
style="text-align: center; vertical-align: top; background-color: rgb(0, 0, 102);"><font
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colspan="5" bgcolor="#ccffff">
<center><font face="Arial,Helvetica"><small><br>
<a href="preview.htm#Miracle_Gro_Fined"><big><big>Scotts
Miracle-Gro Fined $12.5
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href="hawkeye.htm">News
of the Occupy
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style="color: rgb(255, 255, 0);"><span style="font-weight: bold;">Keyboards,
Synthesizers, Guitars, Amps,
Music Stands, and Accessories</span></big><span
style="font-weight: bold;"><br>
</span><img alt="Fender Guitar" src="fg1.jpg"
style="width: 100px; height: 50px;"><br>
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<tr>
<td style="text-align: center; vertical-align: middle;"><small><a
href="Yamaha,%20Roland,%20Korg,%20and%20Casio%20Synthesizers%20and%20Keyboards.html">Keyboards</a><br>
<a
href="Yamaha,%20Roland,%20Korg,%20and%20Casio%20Synthesizers%20and%20Keyboards.html">Synthesizers</a></small>
<br>
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<td style="text-align: center; vertical-align: middle;"><a
href="Fender%20Guitars,%20Schecter%20Guitars%20and%20Other%20Great%20Guitars.html"><small>Guitars<br>
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<td style="text-align: center; vertical-align: middle;"><small><a
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href="Guitar%20Amps.html"><small>Guitar
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<a href="Guitar%20Accessories.html"><small>Learnig Materials</small></a><br>
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<td style="text-align: center; vertical-align: middle;"><a
href="Studio%20Monitors.html"><small>Studio
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Backyard Nature Specialist - Bird Feeding, Bird Feeders, Bird
Identification.
![Welcome to Backyard Nature Specialist Web Site!](banner2e.jpg)
**On the Web Since 1998**
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| --- |
| birdborder
**Backyard Bird Feeding**Pure,
Honest,
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Its one of the few hobbies left that makes no distinctions between the
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balance that a connection with nature brings to the human soul.
There's something soothing about seeing
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or a colorful butterfly examining your garden. Perhaps the secret
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Red Tail Hawk
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[Scotts
Miracle-Gro Fined $12.5
Million Dollars For
Knowingly Selling Poisoned Bird Seed](preview.htm#Miracle_Gro_Fined)
[News
of the Occupy
Movement and the Issues in Need of Change](hawkeye.htm)
|
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Synthesizers, Guitars, Amps,
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[Synthesizers](Yamaha,%20Roland,%20Korg,%20and%20Casio%20Synthesizers%20and%20Keyboards.html)
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---
Site constructed
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Copyright © 1998 -
2012 all rights reserved.
---
---
**This page last updated
May, 2012**
[Email
Rick - Backyard Nature Specialist](form1.htm)
The number below represents
how many **nature lovers have visited this site since
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| http://my.pclink.com/~rlovgren/ |
<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="UTF-8">
<meta http-equiv="X-UA-Compatible" content="IE=edge">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<style>
body{
font-family: 'Montserrat', sans-serif;
}
.banana{
text-align: center;
background-color: #eed64c;
padding: 2rem;
margin: auto;
border-radius: 2rem;
font-size: 40px;
}
footer{
text-align: center;
background-color: #F59E0B;
margin: auto;
padding: 2rem;
border-radius: 2rem;
}
textarea{
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margin: 2rem 25% 2rem;
height: 10vh;
width: 50%;
padding: 1rem;
}
#output{
border: 1px solid black;
height: 10vh;
width: 50%;
margin: 2rem 25% 2rem;
padding: 1rem;
}
#btn-translate{
background-color: #F59E0B;
color: white;
padding: 0.5rem;
/* margin: 1rem 25% 1rem; */
border-radius: 1rem;
}
.back{
background-color: #D1D5DB;
border-radius: 1rem;
margin: 2rem 0rem 2rem;
padding: 1rem ;
text-align: center;
}
</style>
<title>project | Ebonics</title>
</head>
<body>
<h1 class="banana">Ebonics Translator</h1>
<div class="back">
<textarea id="txt-input" placeholder="Input your text so that we convert it to ebonics "></textarea>
<button id="btn-translate">Transalate</button>
<div style="font-size: larger; padding: 1rem; ">Translated Text To Ebonics👇</div>
<textarea readonly id="output"></textarea>
<script src="main.js" type="text/javascript"></script>
</div>
<footer>
<h1 style="font-size: 40px;"><b>ABOUT</b></h1>
<p style="font-size: larger;">Are you a fan of ebonics? Did you know that the gibberish they say is an actual language. Use the translator to convert your text from English to ebonics speak or language.</p>
</footer>
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body{
font-family: 'Montserrat', sans-serif;
}
.banana{
text-align: center;
background-color: #eed64c;
padding: 2rem;
margin: auto;
border-radius: 2rem;
font-size: 40px;
}
footer{
text-align: center;
background-color: #F59E0B;
margin: auto;
padding: 2rem;
border-radius: 2rem;
}
textarea{
display: block;
margin: 2rem 25% 2rem;
height: 10vh;
width: 50%;
padding: 1rem;
}
#output{
border: 1px solid black;
height: 10vh;
width: 50%;
margin: 2rem 25% 2rem;
padding: 1rem;
}
#btn-translate{
background-color: #F59E0B;
color: white;
padding: 0.5rem;
/\* margin: 1rem 25% 1rem; \*/
border-radius: 1rem;
}
.back{
background-color: #D1D5DB;
border-radius: 1rem;
margin: 2rem 0rem 2rem;
padding: 1rem ;
text-align: center;
}
project | Ebonics
# Ebonics Translator
Transalate
Translated Text To Ebonics👇
# **ABOUT**
Are you a fan of ebonics? Did you know that the gibberish they say is an actual language. Use the translator to convert your text from English to ebonics speak or language.
| https://ebonicstranslator.netlify.app/ |
<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN"
"http://www.w3.org/TR/REC-html40/loose-dtd">
<html>
<head>
<title>Constellations</title>
</head>
<body bgcolor="#000000" text="#99FFFF" link="#FFFF66"
vlink="#FFFF66">
<h1 align=center>THE CONSTELLATIONS</h1>
<h2 align=center><img src="aql-strip.jpg" alt="Aquila"></h2>
<h2 align=center>From <a href="/">Jim Kaler</a>'s <a href=
"sowlist.html"><i>STARS</i></a>.</h2>
<h3 align=center>This site is linked to <a
href="cm.html"><i>Constellation Maps</i></a>.</h3>
<h3 align=center><i>The Constellations</i> thanks more than two
million visitors.</h3>
<h3 align=center>A Brief Introduction</h3>
<p>
Constellations are named patterns of stars. All societies
created them. The classical -- "ancient" -- constellations that
populate our sky began in the lands of the middle east thousands
of years ago, their origins largely lost to time. They passed
through the hands of the ancient Greeks, who overlaid them with
their legends and codified them in story and verse. During Roman
times they were assigned Latin names. <br><br>
The 48 ancient constellations single out only the bright
patterns. From around 1600 to 1800, post-Copernican astronomers
invented hosts of "modern" constellations from the faint stars
that lie between the classical figures, from pieces of ancient
constellations, and from the stars that occupy the part of the
southern sky that could not be seen from classical lands. They
also separated the ship <a href="arg-b.html">Argo</a> into three
parts, yielding 50 ancient constellations. <br><br>
In the early twentieth century, the International Astronomical
Union (IAU) adopted 38 of the modern constellations and drew
rectangular borders around all 88. Many of these contain
informal constellations, or "asterisms," that are often the first
to be learned, <a href="uma-p.html">Ursa Major</a> holding the
"<a href="uma-bd-p.html">Big Dipper</a>" and so on. Other
asterisms, like the <a href="wintri2-p.html">Winter Triangle</a>,
cut across constellation boundaries. Some constellations look
like what they are supposed to represent, but most do not.
Constellations, both ancient and modern, are generally meant to
honor and represent, not to portray. <br><br>
The constellations play an important role in modern astronomy.
They bring order to the sky by dividing it into smaller segments,
providing a base for naming celestial objects. Though the
brighter stars commonly carry "<a href="starname.html">proper
names</a>" that come mostly from Arabic, they are also assigned
<a href="starname.html#greek">Greek letters</a> and <a
href="starname.html#flamsteed">Arabic numbers</a> to which are
affixed the Latin possessive forms of the constellation names, <a
href="vega.html">Vega</a>, for example, also known as "Alpha of
Lyra," or "Alpha Lyrae." The IAU also adopted three-letter
abbreviations for all the constellations and their possessives,
Vega thus becoming Alpha Lyr.
The accepted constellations are listed alphabetically in the
table below. The columns give, in order: <br>
<ul>
<li> The constellation name.
<li> The constellation's meaning (if appropriate, linked to a
tale in <a href="essay.html"><i>Stellar Stories</i></a>).
<li> The Latin possessive form.
<li> The three-letter abbreviation.
<li> The <a href="../celsph.html">location</a> (linked to its <a
href="cm.html">Constellation Map</a>), as follows:
<ul>
<li> E: Equatorial; lying on the <a
href="../celsph.html">celestial equator</a>
<li> EN: Equatorial north; lying between the celestial equator
and 45 degrees north of the equator.
<li> NP: North polar; north of 45 degrees north of the
celestial equator; circumpolar for northern latitudes, not rising
for far southern latitudes.
<li> ES: Equatorial south; lying between the celestial equator
and 45 degrees south of the equator.
<li> SP: South polar; south of 45 degrees south of the
celestial equator; circumpolar for southern latitudes, not rising
for far northern latitudes.
<li> Intermediate positions are indicated by combining
location codes, a constellation lying across the circle 45
degrees north of the celestial equator called EN-NP and so on.
<li> Constellations not on the <a href="cm.html">Constellation
Maps</a> are indicated by an asterisk (*); their positions are
described in the text of the appropriate map.
</ul>
<li> The Luminary, or brightest star by both proper and Greek-
letter name (or number). Many luminaries, especially those of
southern constellations, have no proper name.
<li>Remarks. These include whether the constellation is modern,
references to mythology, some asterisms, and what poles
(equatorial, ecliptic, galactic) the constellation may contain.
<li>The constellations and their luminaries are linked to the
main "<a href="sowlist.html"><i>Stars</i></a>" page. Please
enjoy them, both here and in the nighttime sky.
</ul>
<table border cellspacing=1 cellpadding=1>
<tr valign=top>
<td><font color="#FFCCFF">NAME</font></td>
<td><font color="#FFCCFF">MEANING</font></td>
<td><font color="#FFCCFF">POSSESSIVE</font></td>
<td><font color="#FFCCFF">ABR</font></td>
<td><font color="#FFCCFF">LOC</font></td>
<td><font color="#FFCCFF">LUMINARY</font></td>
<td><font color="#FFCCFF">REMARKS</font></td>
</tr>
<tr valign=top>
<td><a href="andromeda-p.html">Andromeda</a></td>
<td>Chained Lady</td>
<td>Andromedae</td>
<td>And</td>
<td><a href="cm2.html">EN-NP</a></td>
<td><a href="alpheratz.html">Alpheratz</a>=Alpha, <a
href="mirach.html">Mirach</a>=Beta</td>
<td><a href="per-p.html">Perseus</a> myth; Daughter of <a
href="cas-p.html">Cassiopeia</a> and <a href="cepheus-
p.html">Cepheus</a>; <a href="andeep1-p.html">galaxy M
31</a></td>
</tr>
<tr valign=top>
<td><a href="ant-p.html">Antlia</a></td>
<td>Air Pump</td>
<td>Antliae</td>
<td>Ant</td>
<td><a href="cm4.html">ES</a></td>
<td><a href="alphaant.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="aps-p.html">Apus</a></td>
<td>Bird of Paradise</td>
<td>Apodis</td>
<td>Aps</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="alphaaps.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="aqr-p.html">Aquarius</a></td>
<td><a href="capaqr.html">Water Bearer</a></td>
<td>Aquarii</td>
<td>Aqr</td>
<td><a href="cm2.html">ES</a></td>
<td><a href="sadalsuud.html">Sadalsuud</a>=Beta</td>
<td><a href="../celsph.html#zodiac">Zodiac</a>; <a href="aqr-
t.html">Water Jar</a>; wet quarter; <a
href="n7009.html">Saturn</a> and <a href="n7293.html">Helix</a>
Nebulae</td>
</tr>
<tr valign=top>
<td><a href="aquila-p.html">Aquila</a></td>
<td><a href="box.html">Eagle</a></td>
<td>Aquilae</td>
<td>Aql</td>
<td><a href="cm2.html">E</a></td>
<td><a href="altair.html">Altair</a>=Alpha</td>
<td><a href="summertri-p.html">Summer Triangle</a></td>
</tr>
<tr valign=top>
<td><a href="ara-p.html">Ara</a></td>
<td>Altar</td>
<td>Arae</td>
<td>Ara</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="betaara.html">Beta</a></td>
<td>Most southerly ancient</td>
</tr>
<tr valign=top>
<td><a href="aries-p.html">Aries</a></td>
<td>Ram</td>
<td>Arietis</td>
<td>Ari</td>
<td><a href="cm3.html">EN</a></td>
<td><a href="hamal.html">Hamal</a>=Alpha</td>
<td><a href="../celsph.html#zodiac">Zodiac</a></td>
</tr>
<tr valign=top>
<td><a href="auriga-p.html">Auriga</a></td>
<td><a href="chariot.html">Charioteer</a></td>
<td>Aurigae</td>
<td>Aur</td>
<td><a href="cm3.html">EN-NP</a></td>
<td><a href="capella.html">Capella</a>=Alpha</td>
<td>Three "<a href="aur-t.html">Kids</a>"; <a
href="anti.html">Galactic Anticenter"</a></td>
</tr>
<tr valign=top>
<td><a href="boo-p.html">Bootes</a></td>
<td>Herdsman</td>
<td>Bootis</td>
<td>Boo</td>
<td><a href="cm5.html">EN</a></td>
<td><a href="arcturus.html">Arcturus</a>=Alpha</td>
<td>Brightest N. hem. star</td>
</tr>
<tr valign=top>
<td><a href="cae-p.html">Caelum</a></td>
<td>Engraving Tool</td>
<td>Caeli</td>
<td>Cae</td>
<td><a href="cm3.html">ES</a>*</td>
<td><a href="alphacae.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="cam-p.html">Camelopardalis</a></td>
<td>Giraffe</td>
<td>Camelopardalis</td>
<td>Cam</td>
<td><a href="cm1.html">NP</a></td>
<td><a href="betacam.html">Beta</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="cnc-p.html">Cancer</a></td>
<td><a href="crab.html">Crab</a></td>
<td>Cancri</td>
<td>Cnc</td>
<td><a href="cm4.html">EN</a></td>
<td><a href="altarf.html">Al Tarf</a>=Beta</td>
<td><a href="../celsph.html#zodiac">Zodiac</a>; <a href="beehive-
p.html">Beehive Cluster</a></td>
</tr>
<tr valign=top>
<td><a href="cvn1-p.html">Canes Venatici</a></td>
<td>Hunting Dogs</td>
<td>Canum Venaticorum</td>
<td>CVn</td>
<td><a href="cm4.html">EN-NP</a></td>
<td><a href="corcaroli.html">Cor Caroli</a>=Alpha-2</td>
<td>Modern</td>
<td></td>
</tr>
<tr valign=top>
<td><a href="cma-p.html">Canis Major</a></td>
<td><a href="dogs.html">Larger Dog</a></td>
<td>Canis Majoris</td>
<td>CMa</td>
<td><a href="cm3.html">ES</a></td>
<td><a href="sirius.html">Sirius</a>=Alpha</td>
<td><a href="wintri-p.html">Winter Triangle</a></td>
</tr>
<tr valign=top>
<td><a href="cmi-p.html">Canis Minor</a></td>
<td><a href="dogs.html">Smaller Dog</a></td>
<td>Canis Minoris</td>
<td>CMi</td>
<td><a href="cm4.html">EN</a></td>
<td><a href="procyon.html">Procyon</a>=Alpha</td>
<td><a href="wintri-p.html">Winter Triangle</a></td>
</tr>
<tr valign=top>
<td><a href="cap-p.html">Capricornus</a></td>
<td><a href="capaqr.html">Water Goat</a></td>
<td>Capricorni</td>
<td>Cap</td>
<td><a href="cm2.html">ES</a></td>
<td><a href="denebalgedi.html">Deneb Algedi</a>=Delta</td>
<td><a href="../celsph.html#zodiac">Zodiac</a>; wet quarter</td>
</tr>
<tr valign=top>
<td><a href="car-p.html">Carina</a></td>
<td>Keel</td>
<td>Carinae</td>
<td>Car</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="canopus.html">Canopus</a>=Alpha</td>
<td><a href="arg-b.html">Argo</a></td>
</tr>
<tr valign=top>
<td><a href="cas-p.html">Cassiopeia</a></td>
<td>Queen</td>
<td>Cassiopeiae</td>
<td>Cas</td>
<td><a href="cm1.html">NP</a></td>
<td><a href="shedar.html">Shedar</a>=Alpha</td>
<td><a href="per-p.html">Perseus</a> myth; <a href="andromeda-
p.html"> Andromeda</a>'s mother; <a
href="gammacas.html">Gamma</a> can be luminary</td>
</tr>
<tr valign=top>
<td><a href="crux-p.html">Centaurus</a></td>
<td>Centaur</td>
<td>Centauri</td>
<td>Cen</td>
<td><a href="cm5.html">ES-SP</a></td>
<td><a href="rigil-kent.html">Rigil Kentaurus</a>=Alpha</td>
<td><a href="hadar.html">Hadar</a>=Beta first mag.</td>
</tr>
<tr valign=top>
<td><a href="cepheus-p.html">Cepheus</a></td>
<td>King</td>
<td>Cephei</td>
<td>Cep</td>
<td><a href="cm1.html">NP</a></td>
<td><a href="alderamin.html">Alderamin</a>=Alpha</td>
<td><a href="per-p.html">Perseus</a> myth; <a href="andromeda-
p.html">Andromeda</a>'s father</td>
</tr>
<tr valign=top>
<td><a href="cetus-p.html">Cetus</a></td>
<td>Whale/Sea Monster</td>
<td>Ceti</td>
<td>Cet</td>
<td><a href="cm3.html">E</a></td>
<td><a href="denebkaitos.html">Deneb Kaitos</a>=Beta</td>
<td><a href="per-p.html">Perseus</a> myth</td>
</tr>
<tr valign=top>
<td><a href="cha-p.html">Chamaeleon</a></td>
<td>Chameleon</td>
<td>Chamaeleontis</td>
<td>Cha</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="alphacha.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="tra-p.html">Circinus</a></td>
<td>Compasses</td>
<td>Circini</td>
<td>Cir</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="alphacir.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="col-p.html">Columba</a></td>
<td><a href="bb.html">Dove</a></td>
<td>Columbae</td>
<td>Col</td>
<td><a href="cm3.html">ES</a></td>
<td><a href="phact.html">Phact</a>=Alpha</td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="com-p.html">Coma Berenices</a></td>
<td>Berenices Hair</td>
<td>Comae Berenices</td>
<td>Com</td>
<td><a href="cm4.html">EN</a></td>
<td><a href="betacom.html">Beta</a></td>
<td>"Modern" but old; <a href="coma-p.html">Coma Berenices
Cluster</a>; <a href="com-t.html">North Galactic Pole</a></td>
</tr>
<tr valign=top>
<td><a href="cra-p.html">Corona Australis</a></td>
<td><a href="royal.html">Southern Crown</a></td>
<td>Coronae Australis</td>
<td>CrA</td>
<td><a href="cm5.html">ES-SP</a></td>
<td><a href="alfecca.html">Alfecca Meridiana</a>=Alpha; <a
href="betacra.html">Beta</a></td>
<td><a href="sag-p.html">Sagittarius</a>'s crown</td>
</tr>
<tr valign=top>
<td><a href="crb-p.html">Corona Borealis</a></td>
<td><a href="royal.html">Northern Crown</a></td>
<td>Coronae Borealis</td>
<td>CrB</td>
<td><a href="cm5.html">EN</a></td>
<td><a href="alphecca.html">Alphecca</a>=Alpha</td>
<td>Ariadne's Crown</td>
</tr>
<tr valign=top>
<td><a href="corvus-p.html">Corvus</a></td>
<td>Crow, Raven</td>
<td>Corvi</td>
<td>Crv</td>
<td><a href="cm4.html">ES</a></td>
<td><a href="gienah.html">Gienah</a>=Gamma</td>
<td>"Pointers" to <a href="spica.html">Spica</a></td>
</tr>
<tr valign=top>
<td><a href="crt-p.html">Crater</a></td>
<td>Cup</td>
<td>Crateris</td>
<td>Crt</td>
<td><a href="cm4.html">ES</a></td>
<td><a href="deltacrt.html">Delta</a></td>
<td>Very faint</td>
</tr>
<tr valign=top>
<td><a href="crux-p.html">Crux</a></td>
<td>Southern Cross</td>
<td>Crucis</td>
<td>Cru</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="acrux.html">Acrux</a>=Alpha</td>
<td>Modern; icon of southern hemisphere</td>
</tr>
<tr valign=top>
<td><a href="cyg-p.html">Cygnus</a></td>
<td>Swan</td>
<td>Cygni</td>
<td>Cyg</td>
<td><a href="cm2.html">EN-NP</a></td>
<td><a href="deneb.html">Deneb</a>=Alpha</td>
<td>Northern Cross, <a href="summertri-p.html">Summer
Triangle</a></td>
</tr>
<tr valign=top>
<td><a href="del-p.html">Delphinus</a></td>
<td><a href="fox.html">Dolphin</a></td>
<td>Delphini</td>
<td>Del</td>
<td><a href="cm2.html">EN</a></td>
<td><a href="rotanev.html">Rotanev</a>=Beta</td>
<td>Wet quarter</td>
</tr>
<tr valign=top>
<td><a href="dor-p.html">Dorado</a></td>
<td>Swordfish</td>
<td>Doradus</td>
<td>Dor</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="alphador.html">Alpha</a></td>
<td>Modern; <a href="dor-t.html">South Ecliptic Pole</a>; <a
href="hyi-p.html">LMC</a></td>
</tr>
<tr valign=top>
<td><a href="draco-p.html">Draco</a></td>
<td><a href="dragon.html">Dragon</a></td>
<td>Draconis</td>
<td>Dra</td>
<td><a href="cm1.html">NP</a></td>
<td><a href="eltanin.html">Eltanin</a>=Gamma</td>
<td><a href="dra-t.html">North Ecliptic Pole</a>; <a
href="n6543.html">Cat's Eye Nebula</a></td>
</tr>
<tr valign=top>
<td><a href="equ-p.html">Equuleus</a></td>
<td><a href="fox.html">Little Horse</a></td>
<td>Equulei</td>
<td>Eql</td>
<td><a href="cm2.html">EN</a></td>
<td><a href="kitalpha.html">Kitalpha</a>=Alpha</td>
<td>Smallest ancient const.</td>
</tr>
<tr valign=top>
<td><a href="eri-p.html">Eridanus</a></td>
<td>River</td>
<td>Eridani</td>
<td>Eri</td>
<td><a href="cm3.html">ES-SP</a></td>
<td><a href="achernar.html">Achernar</a>=Alpha</td>
<td>Second longest</td>
</tr>
<tr valign=top>
<td><a href="for-p.html">Fornax</a></td>
<td>Furnace</td>
<td>Fornacis</td>
<td>For</td>
<td><a href="cm3.html">ES</a></td>
<td><a href="alphafor.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="gemini-p.html">Gemini</a></td>
<td><a href="twins.html">Twins</a></td>
<td>Geminorum</td>
<td>Gem</td>
<td><a href="cm3.html">EN</a></td>
<td><a href="pollux.html">Pollux</a>=Beta</td>
<td><a href="../celsph.html#zodiac">Zodiac</a>; <a href="gem-
t.html">Summer Solstice</a>; cluster <a href="m35-p.html">M
35</a>; <a href="n2392.html">Eskimo Nebula</a></td>
</tr>
<tr valign=top>
<td><a href="grus-p.html">Grus</a></td>
<td>Crane</td>
<td>Gruis</td>
<td>Gru</td>
<td><a href="cm2.html">ES-SP</a></td>
<td><a href="alnair.html">Al Nair</a>=Alpha</td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="her-p.html">Hercules</a></td>
<td><a href="heroic.html">Hero</a>; Hercules</td>
<td>Herculis</td>
<td>Her</td>
<td><a href="cm5.html">EN</a></td>
<td><a href="kornephoros.html">Kornephoros</a>=Beta</td>
<td>"The Kneeler"; cluster <a href="m13-p.html">M 13</a></td>
</tr>
<tr valign=top>
<td><a href="hor-p.html">Horologium</a></td>
<td>Clock</td>
<td>Horologii</td>
<td>Hor</td>
<td><a href="cm6.html">ES-SP</a>*</td>
<td><a href="alphahor.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="hydra-p.html">Hydra</a></td>
<td>Water Serpent</td>
<td>Hydrae</td>
<td>Hya</td>
<td><a href="cm4.html">E-ES</a></td>
<td><a href="alphard.html">Alphard</a>=Alpha</td>
<td>Longest const.</td>
</tr>
<tr valign=top>
<td><a href="hyi-p.html">Hydrus</a></td>
<td>Water Snake</td>
<td>Hydri</td>
<td>Hyi</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="betahyi.html">Beta</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="ind-p.html">Indus</a></td>
<td>Indian</td>
<td>Indi</td>
<td>Ind</td>
<td><a href="cm2.html">SP</a></td>
<td><a href="persian.html">The Persian</a>=Alpha</td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="lac-p.html">Lacerta</a></td>
<td><a href="liz.html">Lizard</a></td>
<td>Lacertae</td>
<td>Lac</td>
<td><a href="cm2.html">EN-NP</a>*</td>
<td><a href="alphalac.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="leo-p.html">Leo</a></td>
<td><a href="lions.html">Lion</a></td>
<td>Leonis</td>
<td>Leo</td>
<td><a href="cm4.html">EN</a></td>
<td><a href="regulus.html">Regulus</a>=Alpha</td>
<td><a href="../celsph.html#zodiac">Zodiac</a></td>
</tr>
<tr valign=top>
<td><a href="lmi-p.html">Leo Minor</a></td>
<td><a href="lions.html">Smaller Lion</a></td>
<td>Leonis Minoris</td>
<td>LMi</td>
<td><a href="cm4.html">EN</a></td>
<td><a href="praecipua.html">Praecipua</a>=46</td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="lepus-p.html">Lepus</a></td>
<td><a href="bb.html">Hare</a></td>
<td>Leporis</td>
<td>Lep</td>
<td><a href="cm3.html">ES</a></td>
<td><a href="arneb.html">Arneb</a>=Alpha</td>
<td><a href="orion-p.html">Orion</a>'s prey</td>
</tr>
<tr valign=top>
<td><a href="libra-p.html">Libra</a></td>
<td>Scales</td>
<td>Librae</td>
<td>Lib</td>
<td><a href="cm5.html">ES</a></td>
<td><a href="zubenes.html">Zubeneschamali</a>=Beta</td>
<td><a href="../celsph.html#zodiac">Zodiac</a></td>
</tr>
<tr valign=top>
<td><a href="lup-p.html">Lupus</a></td>
<td>Wolf</td>
<td>Lupi</td>
<td>Lup</td>
<td><a href="cm5.html">ES-SP</a></td>
<td><a href="kakkab.html">Alpha</a></td>
<td>Classic odd star <a href="chilup.html">Chi Lup</a></td>
</tr>
<tr valign=top>
<td><a href="lyn-p.html">Lynx</a></td>
<td><a href="liz.html">Lynx</a></td>
<td>Lyncis</td>
<td>Lyn</td>
<td><a href="cm4.html">EN-NP</a>*</td>
<td><a href="alphalyn.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="lyra-p.html">Lyra</a></td>
<td>Lyre</td>
<td>Lyrae</td>
<td>Lyr</td>
<td><a href="cm5.html">EN</a></td>
<td><a href="vega.html">Vega</a>=Alpha</td>
<td><a href="summertri-p.html">Summer Triangle</a>; <a
href="ring-p.html">Ring Nebula</a></td>
</tr>
<tr valign=top>
<td><a href="men-p.html">Mensa</a></td>
<td>Table</td>
<td>Mensae</td>
<td>Men</td>
<td><a href="cm6.html">SP</a>*</td>
<td><a href="alphamen.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="mic-p.html">Microscopium</a></td>
<td>Microscope</td>
<td>Microscopii</td>
<td>Mic</td>
<td><a href="cm2.html">ES</a>*</td>
<td><a href="gammamic.html">Gamma</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="mon-p.html">Monoceros</a></td>
<td><a href="moness.html">Unicorn</a></td>
<td>Monocerotis</td>
<td>Mon</td>
<td><a href="cm3.html">E</a>*</td>
<td><a href="betamon.html">Beta</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="mus-p.html">Musca</a></td>
<td>Fly</td>
<td>Muscae</td>
<td>Mus</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="alphamus.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="nor-p.html">Norma</a></td>
<td>Square</td>
<td>Normae</td>
<td>Nor</td>
<td><a href="cm5.html">ES-SP</a>*</td>
<td><a href="gamma2nor.html">Gamma-2</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="oct-p.html">Octans</a></td>
<td><a href="navigate.html">Octant</a></td>
<td>Octantis</td>
<td>Oct</td>
<td><a href="cm6.html">SP</a>*</td>
<td><a href="nuoct.html">Nu</a></td>
<td>Modern; <a href="oct-t.html">South Celestial Pole</a></td>
</tr>
<tr valign=top>
<td><a href="ophser-p.html">Ophiuchus</a></td>
<td><a href="serpent.html">Serpent Bearer</a></td>
<td>Ophiuchi</td>
<td>Oph</td>
<td><a href="cm5.html">E</a></td>
<td><a href="rasalhague.html">Rasalhague</a>=Alpha</td>
<td>With Serpens; on <a
href="../celsph.html#ecliptic">ecliptic</a>; cluster <a
href="m10-p.html">M 10</a></td>
</tr>
<tr valign=top>
<td><a href="orion-p.html">Orion</a></td>
<td><a href="orihunter.html">Hunter</a>; Orion</td>
<td>Orionis</td>
<td>Ori</td>
<td><a href="cm3.html">E</a></td>
<td><a href="rigel.html">Rigel</a>=Beta</td>
<td><a href="wintri-p.html">Winter Triangle</a>; <a
href="orineb.html">Orion Nebula</a></td>
</tr>
<tr valign=top>
<td><a href="pav-p.html">Pavo</a></td>
<td>Peacock</td>
<td>Pavonis</td>
<td>Pav</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="peacock.html">Peacock</a>=Alpha</td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="pegasus-p.html">Pegasus</a></td>
<td><a href="horse.html">Winged Horse</a></td>
<td>Pegasi</td>
<td>Peg</td>
<td><a href="cm2.html">EN</a></td>
<td><a href="enif.html">Enif</a>=Epsilon</td>
<td><a href="per-p.html">Perseus</a> myth, <a href="peg-square-
p.html">Great Square</a>; cluster <a href="m15-p.html">M
15</a></td>
</tr>
<tr valign=top>
<td><a href="per-p.html">Perseus</a></td>
<td><a href="horse.html">Hero</a>; Perseus</td>
<td>Persei</td>
<td>Per</td>
<td><a href="cm3.html">EN-NP</a></td>
<td><a href="mirfak.html">Mirfak</a>=Alpha</td>
<td>Perseus myth; rescuer of <a href="andromeda-
p.html">Andromeda</a>; <a href="doubclus-p.html">Double
Cluster</a>; <a href="alphper-p.html">Alpha Per Cluster</a></td>
</tr>
<tr valign=top>
<td><a href="phe-p.html">Phoenix</a></td>
<td>Phoenix</td>
<td>Phoenicis</td>
<td>Phe</td>
<td><a href="cm2.html">ES-SP</a></td>
<td><a href="ankaa.html">Ankaa</a>=Alpha</td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="dor-p.html">Pictor</a></td>
<td>Easel</td>
<td>Pictoris</td>
<td>Pic</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="alphapic.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="psc-c-p.html">Pisces</a></td>
<td>Fishes</td>
<td>Piscium</td>
<td>Psc</td>
<td><a href="cm2.html">E-EN</a></td>
<td><a href="kullatnunu.html">Kullat Nunu</a>=Eta</td>
<td><a href="../celsph.html#zodiac">Zodiac</a>; <a href="psc-w-
t.html">Vernal Equinox</a>; <a href="psc-w-t.html">Circlet</a>;
wet quarter</td>
</tr>
<tr valign=top>
<td><a href="psa-p.html">Piscis Austrinus</a></td>
<td>Southern Fish</td>
<td>Piscis Austrini</td>
<td>PsA</td>
<td><a href="cm2.html">ES</a></td>
<td><a href="fomalhaut.html">Fomalhaut</a>=Alpha</td>
<td>Wet quarter</td>
</tr>
<tr valign=top>
<td><a href="pup-p.html">Puppis</a></td>
<td>Stern</td>
<td>Puppis</td>
<td>Pup</td>
<td><a href="cm4.html">ES-SP</a></td>
<td><a href="naos.html">Naos</a>=Zeta</td>
<td><a href="arg-b.html">Argo</a></td>
</tr>
<tr valign=top>
<td><a href="pyx-p.html">Pyxis</a></td>
<td>Compass</td>
<td>Pyxidis</td>
<td>Pyx</td>
<td><a href="cm4.html">ES</a></td>
<td><a href="alphapyx.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="dor-p.html">Reticulum</a></td>
<td>Net</td>
<td>Reticuli</td>
<td>Ret</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="alpharet.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="sagitta-p.html">Sagitta</a></td>
<td><a href="fox.html">Arrow</a></td>
<td>Sagittae</td>
<td>Sge</td>
<td><a href="cm2.html">NE</a></td>
<td><a href="gammasge.html">Gamma</a></td>
<td>Arrow of <a href="her-p.html">Hercules</a>; of Cupid</td>
</tr>
<tr valign=top>
<td><a href="sag-p.html">Sagittarius</a></td>
<td><a href="tea.html">Archer</a></td>
<td>Sagittarii</td>
<td>Sgr</td>
<td><a href="cm5.html">ES</a></td>
<td><a href="kausaus.html">Kaus Australis</a>=Epsilon</td>
<td><a href="../celsph.html#zodiac">Zodiac</a>; <a href="sgr-
t.html">Winter Solstice</a>; Little Milk Dipper; Teapot; <a
href="sgr-t.html">Galactic center</a></td>
</tr>
<tr valign=top>
<td><a href="sco-p.html">Scorpius</a></td>
<td><a href="tea.html">Scorpion</a></td>
<td>Scorpii</td>
<td>Sco</td>
<td><a href="cm5.html">ES</a></td>
<td><a href="antares.html">Antares</a>=Alpha</td>
<td><a href="../celsph.html#zodiac">Zodiac</a></td>
</tr>
<tr valign=top>
<td><a href="scl-p.html">Sculptor</a></td>
<td>Sculptor's Studio</td>
<td>Sculptoris</td>
<td>Scl</td>
<td><a href="cm2.html">ES</a></td>
<td><a href="alphascl.html">Alpha</a></td>
<td>Modern; <a href="scl-t.html">South Galactic Pole</a></td>
</tr>
<tr valign=top>
<td><a href="sct-p.html">Scutum</a></td>
<td><a href="box.html">Shield</a></td>
<td>Scuti</td>
<td>Sct</td>
<td><a href="cm5.html">ES</a></td>
<td><a href="alphasct.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="ophser-p.html">Serpens</a></td>
<td><a href="serpent.html">Serpent</a></td>
<td>Serpentis</td>
<td>Ser</td>
<td><a href="cm5.html">E</a></td>
<td><a href="unukalhai.html">Unukalhai</a>=Alpha</td>
<td>Two parts; with <a href="ophser-p.html">Ophiuchus</a></td>
</tr>
<tr valign=top>
<td><a href="sextans-p.html">Sextans</a></td>
<td><a href="navigate.html">Sextant</a></td>
<td>Sextantis</td>
<td>Sex</td>
<td><a href="cm4.html">E</a></td>
<td><a href="alphasext.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="taurus-p.html">Taurus</a></td>
<td><a href="tau03x-p.html">Bull</a></td>
<td>Tauri</td>
<td>Tau</td>
<td><a href="cm3.html">EN</a></td>
<td><a href="aldebaran.html">Aldebaran</a>= Alpha</td>
<td><a href="../celsph.html#zodiac">Zodiac</a>; <a href="hyades-
p.html">Hyades</a>; <a href="pleiades-p.html">Pleiades</a>; <a
href="tau-t.html">Galactic anticenter</a></td>
</tr>
<tr valign=top>
<td><a href="tel-p.html">Telescopium</a></td>
<td>Telescope</td>
<td>Telescopii</td>
<td>Tel</td>
<td><a href="cm5.html">ES-SP</a></td>
<td><a href="alphatel.html">Alpha</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="tri-p.html">Triangulum</a></td>
<td><a href="triangle.html">Triangle</a></td>
<td>Trianguli</td>
<td>Tri</td>
<td><a href="cm3.html">EN</a></td>
<td><a href="betatri.html">Beta</a></td>
<td><a href="tri-t.html">Galaxy M 33</a></td>
</tr>
<tr valign=top>
<td><a href="tra-p.html">Triangulum Australe</a></td>
<td><a href="triangle.html">Southern Triangle</a></td>
<td>Trianguli Australis</td>
<td>TrA</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="atria.html">Atria</a>=Alpha</td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="hyi-p.html">Tucana</a></td>
<td>Toucan</td>
<td>Tucanae</td>
<td>Tuc</td>
<td><a href="cm6.html">SP</a></td>
<td><a href="alphatuc.html">Alpha</a></td>
<td>Modern; <a href="hyi-p.html">SMC</a>;</td>
</tr>
<tr valign=top>
<td><a href="uma-p.html">Ursa Major</a></td>
<td>Greater Bear</td>
<td>Ursae Majoris</td>
<td>UMa</td>
<td><a href="cm1.html">NP</a></td>
<td><a href="alioth.html">Alioth</a>=Epsilon</td>
<td><a href="uma-bd-p.html">Big Dipper</a>/Plough; <a
href="umaclus-p.html">Ursa Major Cluster</a></td>
</tr>
<tr valign=top>
<td><a href="umi-p.html">Ursa Minor</a></td>
<td>Smaller Bear</td>
<td>Ursae Minoris</td>
<td>UMi</td>
<td><a href="cm1.html">NP</a></td>
<td><a href="polaris.html">Polaris</a>=Alpha </td>
<td>Little Dipper; <a href="umi-t.html">North Celestial
Pole</a></td>
</tr>
<tr valign=top>
<td><a href="vel-p.html">Vela</a></td>
<td>Sails</td>
<td>Velorum</td>
<td>Vel</td>
<td><a href="cm4.html">ES-SP</a></td>
<td><a href="regor.html">Regor</a>=Gamma</td>
<td><a href="arg-b.html">Argo</a></td>
</tr>
<tr valign=top>
<td><a href="virgo-p.html">Virgo</a></td>
<td>Maiden</td>
<td>Virginis</td>
<td>Vir</td>
<td><a href="cm4.html">E</a></td>
<td><a href="spica.html">Spica</a>=Alpha</td>
<td><a href="../celsph.html#zodiac">Zodiac</a>; <a href="leovir-
t.html">Autumnal Equinox</a></td>
</tr>
<tr valign=top>
<td><a href="vol-p.html">Volans</a></td>
<td>Flying Fish</td>
<td>Volantis</td>
<td>Vol</td>
<td><a href="cm6.html">SP</a>*</td>
<td><a href="gammavol.html">Gamma</a></td>
<td>Modern</td>
</tr>
<tr valign=top>
<td><a href="vul-p.html">Vulpecula</a></td>
<td><a href="fox.html">Fox</a></td>
<td>Vulpeculae</td>
<td>Vul</td>
<td><a href="cm2.html">EN</a>*</td>
<td><a href="anser.html">Anser</a>=Alpha</td>
<td>Modern; <a href="cthng-p.html">Coathanger</a> non-cluster; <a
href="m27.html">Dumbbell Nebula</a></td>
</tr>
</table>
<br>
*Not on star map; position indicated in text.
<br><br>
<table bgcolor="#33CCFF">
<tr><td>
<h5>
<a href="http://validator.w3.org/"><img border=0 align=right
src="http://validator.w3.org/images/vh40.gif"
alt="Valid HTML 4.0!" height=31 width=88></a>
<font color="000000">
<i>Copyright © James B. Kaler, all rights reserved.
These contents are the property of the author and may not be
reproduced in whole or in part without the author's consent
except in fair use for educational purposes. This page was last
modified on 14 February, 2014. Opening illustration: <a
href="aquila.html">Aquila</a>, from John Flamsteed's "Atlas
Coelestis," 1781 edition, courtesy of the Rare Book and Special
Collections Library, University of Illinois at Urbana-Champaign.
Thanks to visitor number <a title="blogger counters"
href="http://www.statcounter.com/blogger/"
target="_blank"><img
src="http://c.statcounter.com/5047460/0/0e8805c6/0/"
alt="blogger counters" border="0"></a>.</i>
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</h5>
</td></tr>
</table>
</body>
</html>
|
Constellations
# THE CONSTELLATIONS
## Aquila
## From [Jim Kaler](/)'s [*STARS*](sowlist.html).
### This site is linked to [*Constellation Maps*](cm.html).
### *The Constellations* thanks more than two
million visitors.
### A Brief Introduction
Constellations are named patterns of stars. All societies
created them. The classical -- "ancient" -- constellations that
populate our sky began in the lands of the middle east thousands
of years ago, their origins largely lost to time. They passed
through the hands of the ancient Greeks, who overlaid them with
their legends and codified them in story and verse. During Roman
times they were assigned Latin names.
The 48 ancient constellations single out only the bright
patterns. From around 1600 to 1800, post-Copernican astronomers
invented hosts of "modern" constellations from the faint stars
that lie between the classical figures, from pieces of ancient
constellations, and from the stars that occupy the part of the
southern sky that could not be seen from classical lands. They
also separated the ship [Argo](arg-b.html) into three
parts, yielding 50 ancient constellations.
In the early twentieth century, the International Astronomical
Union (IAU) adopted 38 of the modern constellations and drew
rectangular borders around all 88. Many of these contain
informal constellations, or "asterisms," that are often the first
to be learned, [Ursa Major](uma-p.html) holding the
"[Big Dipper](uma-bd-p.html)" and so on. Other
asterisms, like the [Winter Triangle](wintri2-p.html),
cut across constellation boundaries. Some constellations look
like what they are supposed to represent, but most do not.
Constellations, both ancient and modern, are generally meant to
honor and represent, not to portray.
The constellations play an important role in modern astronomy.
They bring order to the sky by dividing it into smaller segments,
providing a base for naming celestial objects. Though the
brighter stars commonly carry "[proper
names](starname.html)" that come mostly from Arabic, they are also assigned
[Greek letters](starname.html#greek) and [Arabic numbers](starname.html#flamsteed) to which are
affixed the Latin possessive forms of the constellation names, [Vega](vega.html), for example, also known as "Alpha of
Lyra," or "Alpha Lyrae." The IAU also adopted three-letter
abbreviations for all the constellations and their possessives,
Vega thus becoming Alpha Lyr.
The accepted constellations are listed alphabetically in the
table below. The columns give, in order:
* The constellation name.
* The constellation's meaning (if appropriate, linked to a
tale in [*Stellar Stories*](essay.html)).
* The Latin possessive form.
* The three-letter abbreviation.
* The [location](../celsph.html) (linked to its [Constellation Map](cm.html)), as follows:
+ E: Equatorial; lying on the [celestial equator](../celsph.html)+ EN: Equatorial north; lying between the celestial equator
and 45 degrees north of the equator.
+ NP: North polar; north of 45 degrees north of the
celestial equator; circumpolar for northern latitudes, not rising
for far southern latitudes.
+ ES: Equatorial south; lying between the celestial equator
and 45 degrees south of the equator.
+ SP: South polar; south of 45 degrees south of the
celestial equator; circumpolar for southern latitudes, not rising
for far northern latitudes.
+ Intermediate positions are indicated by combining
location codes, a constellation lying across the circle 45
degrees north of the celestial equator called EN-NP and so on.
+ Constellations not on the [Constellation
Maps](cm.html) are indicated by an asterisk (\*); their positions are
described in the text of the appropriate map.* The Luminary, or brightest star by both proper and Greek-
letter name (or number). Many luminaries, especially those of
southern constellations, have no proper name.
* Remarks. These include whether the constellation is modern,
references to mythology, some asterisms, and what poles
(equatorial, ecliptic, galactic) the constellation may contain.
* The constellations and their luminaries are linked to the
main "[*Stars*](sowlist.html)" page. Please
enjoy them, both here and in the nighttime sky.
| | | | | | | |
| --- | --- | --- | --- | --- | --- | --- |
| NAME | MEANING | POSSESSIVE | ABR | LOC | LUMINARY | REMARKS |
| [Andromeda](andromeda-p.html) | Chained Lady | Andromedae | And | [EN-NP](cm2.html) | [Alpheratz](alpheratz.html)=Alpha, [Mirach](mirach.html)=Beta | [Perseus](per-p.html) myth; Daughter of [Cassiopeia](cas-p.html) and [Cepheus](cepheus-
p.html); [galaxy M
31](andeep1-p.html) |
| [Antlia](ant-p.html) | Air Pump | Antliae | Ant | [ES](cm4.html) | [Alpha](alphaant.html) | Modern |
| [Apus](aps-p.html) | Bird of Paradise | Apodis | Aps | [SP](cm6.html) | [Alpha](alphaaps.html) | Modern |
| [Aquarius](aqr-p.html) | [Water Bearer](capaqr.html) | Aquarii | Aqr | [ES](cm2.html) | [Sadalsuud](sadalsuud.html)=Beta | [Zodiac](../celsph.html#zodiac); [Water Jar](aqr-
t.html); wet quarter; [Saturn](n7009.html) and [Helix](n7293.html)
Nebulae |
| [Aquila](aquila-p.html) | [Eagle](box.html) | Aquilae | Aql | [E](cm2.html) | [Altair](altair.html)=Alpha | [Summer Triangle](summertri-p.html) |
| [Ara](ara-p.html) | Altar | Arae | Ara | [SP](cm6.html) | [Beta](betaara.html) | Most southerly ancient |
| [Aries](aries-p.html) | Ram | Arietis | Ari | [EN](cm3.html) | [Hamal](hamal.html)=Alpha | [Zodiac](../celsph.html#zodiac) |
| [Auriga](auriga-p.html) | [Charioteer](chariot.html) | Aurigae | Aur | [EN-NP](cm3.html) | [Capella](capella.html)=Alpha | Three "[Kids](aur-t.html)"; [Galactic Anticenter"](anti.html) |
| [Bootes](boo-p.html) | Herdsman | Bootis | Boo | [EN](cm5.html) | [Arcturus](arcturus.html)=Alpha | Brightest N. hem. star |
| [Caelum](cae-p.html) | Engraving Tool | Caeli | Cae | [ES](cm3.html)\* | [Alpha](alphacae.html) | Modern |
| [Camelopardalis](cam-p.html) | Giraffe | Camelopardalis | Cam | [NP](cm1.html) | [Beta](betacam.html) | Modern |
| [Cancer](cnc-p.html) | [Crab](crab.html) | Cancri | Cnc | [EN](cm4.html) | [Al Tarf](altarf.html)=Beta | [Zodiac](../celsph.html#zodiac); [Beehive Cluster](beehive-
p.html) |
| [Canes Venatici](cvn1-p.html) | Hunting Dogs | Canum Venaticorum | CVn | [EN-NP](cm4.html) | [Cor Caroli](corcaroli.html)=Alpha-2 | Modern | |
| [Canis Major](cma-p.html) | [Larger Dog](dogs.html) | Canis Majoris | CMa | [ES](cm3.html) | [Sirius](sirius.html)=Alpha | [Winter Triangle](wintri-p.html) |
| [Canis Minor](cmi-p.html) | [Smaller Dog](dogs.html) | Canis Minoris | CMi | [EN](cm4.html) | [Procyon](procyon.html)=Alpha | [Winter Triangle](wintri-p.html) |
| [Capricornus](cap-p.html) | [Water Goat](capaqr.html) | Capricorni | Cap | [ES](cm2.html) | [Deneb Algedi](denebalgedi.html)=Delta | [Zodiac](../celsph.html#zodiac); wet quarter |
| [Carina](car-p.html) | Keel | Carinae | Car | [SP](cm6.html) | [Canopus](canopus.html)=Alpha | [Argo](arg-b.html) |
| [Cassiopeia](cas-p.html) | Queen | Cassiopeiae | Cas | [NP](cm1.html) | [Shedar](shedar.html)=Alpha | [Perseus](per-p.html) myth; [Andromeda](andromeda-
p.html)'s mother; [Gamma](gammacas.html) can be luminary |
| [Centaurus](crux-p.html) | Centaur | Centauri | Cen | [ES-SP](cm5.html) | [Rigil Kentaurus](rigil-kent.html)=Alpha | [Hadar](hadar.html)=Beta first mag. |
| [Cepheus](cepheus-p.html) | King | Cephei | Cep | [NP](cm1.html) | [Alderamin](alderamin.html)=Alpha | [Perseus](per-p.html) myth; [Andromeda](andromeda-
p.html)'s father |
| [Cetus](cetus-p.html) | Whale/Sea Monster | Ceti | Cet | [E](cm3.html) | [Deneb Kaitos](denebkaitos.html)=Beta | [Perseus](per-p.html) myth |
| [Chamaeleon](cha-p.html) | Chameleon | Chamaeleontis | Cha | [SP](cm6.html) | [Alpha](alphacha.html) | Modern |
| [Circinus](tra-p.html) | Compasses | Circini | Cir | [SP](cm6.html) | [Alpha](alphacir.html) | Modern |
| [Columba](col-p.html) | [Dove](bb.html) | Columbae | Col | [ES](cm3.html) | [Phact](phact.html)=Alpha | Modern |
| [Coma Berenices](com-p.html) | Berenices Hair | Comae Berenices | Com | [EN](cm4.html) | [Beta](betacom.html) | "Modern" but old; [Coma Berenices
Cluster](coma-p.html); [North Galactic Pole](com-t.html) |
| [Corona Australis](cra-p.html) | [Southern Crown](royal.html) | Coronae Australis | CrA | [ES-SP](cm5.html) | [Alfecca Meridiana](alfecca.html)=Alpha; [Beta](betacra.html) | [Sagittarius](sag-p.html)'s crown |
| [Corona Borealis](crb-p.html) | [Northern Crown](royal.html) | Coronae Borealis | CrB | [EN](cm5.html) | [Alphecca](alphecca.html)=Alpha | Ariadne's Crown |
| [Corvus](corvus-p.html) | Crow, Raven | Corvi | Crv | [ES](cm4.html) | [Gienah](gienah.html)=Gamma | "Pointers" to [Spica](spica.html) |
| [Crater](crt-p.html) | Cup | Crateris | Crt | [ES](cm4.html) | [Delta](deltacrt.html) | Very faint |
| [Crux](crux-p.html) | Southern Cross | Crucis | Cru | [SP](cm6.html) | [Acrux](acrux.html)=Alpha | Modern; icon of southern hemisphere |
| [Cygnus](cyg-p.html) | Swan | Cygni | Cyg | [EN-NP](cm2.html) | [Deneb](deneb.html)=Alpha | Northern Cross, [Summer
Triangle](summertri-p.html) |
| [Delphinus](del-p.html) | [Dolphin](fox.html) | Delphini | Del | [EN](cm2.html) | [Rotanev](rotanev.html)=Beta | Wet quarter |
| [Dorado](dor-p.html) | Swordfish | Doradus | Dor | [SP](cm6.html) | [Alpha](alphador.html) | Modern; [South Ecliptic Pole](dor-t.html); [LMC](hyi-p.html) |
| [Draco](draco-p.html) | [Dragon](dragon.html) | Draconis | Dra | [NP](cm1.html) | [Eltanin](eltanin.html)=Gamma | [North Ecliptic Pole](dra-t.html); [Cat's Eye Nebula](n6543.html) |
| [Equuleus](equ-p.html) | [Little Horse](fox.html) | Equulei | Eql | [EN](cm2.html) | [Kitalpha](kitalpha.html)=Alpha | Smallest ancient const. |
| [Eridanus](eri-p.html) | River | Eridani | Eri | [ES-SP](cm3.html) | [Achernar](achernar.html)=Alpha | Second longest |
| [Fornax](for-p.html) | Furnace | Fornacis | For | [ES](cm3.html) | [Alpha](alphafor.html) | Modern |
| [Gemini](gemini-p.html) | [Twins](twins.html) | Geminorum | Gem | [EN](cm3.html) | [Pollux](pollux.html)=Beta | [Zodiac](../celsph.html#zodiac); [Summer Solstice](gem-
t.html); cluster [M
35](m35-p.html); [Eskimo Nebula](n2392.html) |
| [Grus](grus-p.html) | Crane | Gruis | Gru | [ES-SP](cm2.html) | [Al Nair](alnair.html)=Alpha | Modern |
| [Hercules](her-p.html) | [Hero](heroic.html); Hercules | Herculis | Her | [EN](cm5.html) | [Kornephoros](kornephoros.html)=Beta | "The Kneeler"; cluster [M 13](m13-p.html) |
| [Horologium](hor-p.html) | Clock | Horologii | Hor | [ES-SP](cm6.html)\* | [Alpha](alphahor.html) | Modern |
| [Hydra](hydra-p.html) | Water Serpent | Hydrae | Hya | [E-ES](cm4.html) | [Alphard](alphard.html)=Alpha | Longest const. |
| [Hydrus](hyi-p.html) | Water Snake | Hydri | Hyi | [SP](cm6.html) | [Beta](betahyi.html) | Modern |
| [Indus](ind-p.html) | Indian | Indi | Ind | [SP](cm2.html) | [The Persian](persian.html)=Alpha | Modern |
| [Lacerta](lac-p.html) | [Lizard](liz.html) | Lacertae | Lac | [EN-NP](cm2.html)\* | [Alpha](alphalac.html) | Modern |
| [Leo](leo-p.html) | [Lion](lions.html) | Leonis | Leo | [EN](cm4.html) | [Regulus](regulus.html)=Alpha | [Zodiac](../celsph.html#zodiac) |
| [Leo Minor](lmi-p.html) | [Smaller Lion](lions.html) | Leonis Minoris | LMi | [EN](cm4.html) | [Praecipua](praecipua.html)=46 | Modern |
| [Lepus](lepus-p.html) | [Hare](bb.html) | Leporis | Lep | [ES](cm3.html) | [Arneb](arneb.html)=Alpha | [Orion](orion-p.html)'s prey |
| [Libra](libra-p.html) | Scales | Librae | Lib | [ES](cm5.html) | [Zubeneschamali](zubenes.html)=Beta | [Zodiac](../celsph.html#zodiac) |
| [Lupus](lup-p.html) | Wolf | Lupi | Lup | [ES-SP](cm5.html) | [Alpha](kakkab.html) | Classic odd star [Chi Lup](chilup.html) |
| [Lynx](lyn-p.html) | [Lynx](liz.html) | Lyncis | Lyn | [EN-NP](cm4.html)\* | [Alpha](alphalyn.html) | Modern |
| [Lyra](lyra-p.html) | Lyre | Lyrae | Lyr | [EN](cm5.html) | [Vega](vega.html)=Alpha | [Summer Triangle](summertri-p.html); [Ring Nebula](ring-p.html) |
| [Mensa](men-p.html) | Table | Mensae | Men | [SP](cm6.html)\* | [Alpha](alphamen.html) | Modern |
| [Microscopium](mic-p.html) | Microscope | Microscopii | Mic | [ES](cm2.html)\* | [Gamma](gammamic.html) | Modern |
| [Monoceros](mon-p.html) | [Unicorn](moness.html) | Monocerotis | Mon | [E](cm3.html)\* | [Beta](betamon.html) | Modern |
| [Musca](mus-p.html) | Fly | Muscae | Mus | [SP](cm6.html) | [Alpha](alphamus.html) | Modern |
| [Norma](nor-p.html) | Square | Normae | Nor | [ES-SP](cm5.html)\* | [Gamma-2](gamma2nor.html) | Modern |
| [Octans](oct-p.html) | [Octant](navigate.html) | Octantis | Oct | [SP](cm6.html)\* | [Nu](nuoct.html) | Modern; [South Celestial Pole](oct-t.html) |
| [Ophiuchus](ophser-p.html) | [Serpent Bearer](serpent.html) | Ophiuchi | Oph | [E](cm5.html) | [Rasalhague](rasalhague.html)=Alpha | With Serpens; on [ecliptic](../celsph.html#ecliptic); cluster [M 10](m10-p.html) |
| [Orion](orion-p.html) | [Hunter](orihunter.html); Orion | Orionis | Ori | [E](cm3.html) | [Rigel](rigel.html)=Beta | [Winter Triangle](wintri-p.html); [Orion Nebula](orineb.html) |
| [Pavo](pav-p.html) | Peacock | Pavonis | Pav | [SP](cm6.html) | [Peacock](peacock.html)=Alpha | Modern |
| [Pegasus](pegasus-p.html) | [Winged Horse](horse.html) | Pegasi | Peg | [EN](cm2.html) | [Enif](enif.html)=Epsilon | [Perseus](per-p.html) myth, [Great Square](peg-square-
p.html); cluster [M
15](m15-p.html) |
| [Perseus](per-p.html) | [Hero](horse.html); Perseus | Persei | Per | [EN-NP](cm3.html) | [Mirfak](mirfak.html)=Alpha | Perseus myth; rescuer of [Andromeda](andromeda-
p.html); [Double
Cluster](doubclus-p.html); [Alpha Per Cluster](alphper-p.html) |
| [Phoenix](phe-p.html) | Phoenix | Phoenicis | Phe | [ES-SP](cm2.html) | [Ankaa](ankaa.html)=Alpha | Modern |
| [Pictor](dor-p.html) | Easel | Pictoris | Pic | [SP](cm6.html) | [Alpha](alphapic.html) | Modern |
| [Pisces](psc-c-p.html) | Fishes | Piscium | Psc | [E-EN](cm2.html) | [Kullat Nunu](kullatnunu.html)=Eta | [Zodiac](../celsph.html#zodiac); [Vernal Equinox](psc-w-
t.html); [Circlet](psc-w-t.html);
wet quarter |
| [Piscis Austrinus](psa-p.html) | Southern Fish | Piscis Austrini | PsA | [ES](cm2.html) | [Fomalhaut](fomalhaut.html)=Alpha | Wet quarter |
| [Puppis](pup-p.html) | Stern | Puppis | Pup | [ES-SP](cm4.html) | [Naos](naos.html)=Zeta | [Argo](arg-b.html) |
| [Pyxis](pyx-p.html) | Compass | Pyxidis | Pyx | [ES](cm4.html) | [Alpha](alphapyx.html) | Modern |
| [Reticulum](dor-p.html) | Net | Reticuli | Ret | [SP](cm6.html) | [Alpha](alpharet.html) | Modern |
| [Sagitta](sagitta-p.html) | [Arrow](fox.html) | Sagittae | Sge | [NE](cm2.html) | [Gamma](gammasge.html) | Arrow of [Hercules](her-p.html); of Cupid |
| [Sagittarius](sag-p.html) | [Archer](tea.html) | Sagittarii | Sgr | [ES](cm5.html) | [Kaus Australis](kausaus.html)=Epsilon | [Zodiac](../celsph.html#zodiac); [Winter Solstice](sgr-
t.html); Little Milk Dipper; Teapot; [Galactic center](sgr-t.html) |
| [Scorpius](sco-p.html) | [Scorpion](tea.html) | Scorpii | Sco | [ES](cm5.html) | [Antares](antares.html)=Alpha | [Zodiac](../celsph.html#zodiac) |
| [Sculptor](scl-p.html) | Sculptor's Studio | Sculptoris | Scl | [ES](cm2.html) | [Alpha](alphascl.html) | Modern; [South Galactic Pole](scl-t.html) |
| [Scutum](sct-p.html) | [Shield](box.html) | Scuti | Sct | [ES](cm5.html) | [Alpha](alphasct.html) | Modern |
| [Serpens](ophser-p.html) | [Serpent](serpent.html) | Serpentis | Ser | [E](cm5.html) | [Unukalhai](unukalhai.html)=Alpha | Two parts; with [Ophiuchus](ophser-p.html) |
| [Sextans](sextans-p.html) | [Sextant](navigate.html) | Sextantis | Sex | [E](cm4.html) | [Alpha](alphasext.html) | Modern |
| [Taurus](taurus-p.html) | [Bull](tau03x-p.html) | Tauri | Tau | [EN](cm3.html) | [Aldebaran](aldebaran.html)= Alpha | [Zodiac](../celsph.html#zodiac); [Hyades](hyades-
p.html); [Pleiades](pleiades-p.html); [Galactic anticenter](tau-t.html) |
| [Telescopium](tel-p.html) | Telescope | Telescopii | Tel | [ES-SP](cm5.html) | [Alpha](alphatel.html) | Modern |
| [Triangulum](tri-p.html) | [Triangle](triangle.html) | Trianguli | Tri | [EN](cm3.html) | [Beta](betatri.html) | [Galaxy M 33](tri-t.html) |
| [Triangulum Australe](tra-p.html) | [Southern Triangle](triangle.html) | Trianguli Australis | TrA | [SP](cm6.html) | [Atria](atria.html)=Alpha | Modern |
| [Tucana](hyi-p.html) | Toucan | Tucanae | Tuc | [SP](cm6.html) | [Alpha](alphatuc.html) | Modern; [SMC](hyi-p.html); |
| [Ursa Major](uma-p.html) | Greater Bear | Ursae Majoris | UMa | [NP](cm1.html) | [Alioth](alioth.html)=Epsilon | [Big Dipper](uma-bd-p.html)/Plough; [Ursa Major Cluster](umaclus-p.html) |
| [Ursa Minor](umi-p.html) | Smaller Bear | Ursae Minoris | UMi | [NP](cm1.html) | [Polaris](polaris.html)=Alpha | Little Dipper; [North Celestial
Pole](umi-t.html) |
| [Vela](vel-p.html) | Sails | Velorum | Vel | [ES-SP](cm4.html) | [Regor](regor.html)=Gamma | [Argo](arg-b.html) |
| [Virgo](virgo-p.html) | Maiden | Virginis | Vir | [E](cm4.html) | [Spica](spica.html)=Alpha | [Zodiac](../celsph.html#zodiac); [Autumnal Equinox](leovir-
t.html) |
| [Volans](vol-p.html) | Flying Fish | Volantis | Vol | [SP](cm6.html)\* | [Gamma](gammavol.html) | Modern |
| [Vulpecula](vul-p.html) | [Fox](fox.html) | Vulpeculae | Vul | [EN](cm2.html)\* | [Anser](anser.html)=Alpha | Modern; [Coathanger](cthng-p.html) non-cluster; [Dumbbell Nebula](m27.html) |
\*Not on star map; position indicated in text.
| |
| --- |
|
[Valid HTML 4.0!](http://validator.w3.org/)
*Copyright © James B. Kaler, all rights reserved.
These contents are the property of the author and may not be
reproduced in whole or in part without the author's consent
except in fair use for educational purposes. This page was last
modified on 14 February, 2014. Opening illustration: [Aquila](aquila.html), from John Flamsteed's "Atlas
Coelestis," 1781 edition, courtesy of the Rare Book and Special
Collections Library, University of Illinois at Urbana-Champaign.
Thanks to visitor number [blogger counters](http://www.statcounter.com/blogger/ "blogger counters").*
|
| http://stars.astro.illinois.edu/Sow/const.html |
<html>
<head><title>SerenityOS: From zero to HTML in a year</title></head>
<body>
<h1>SerenityOS: From zero to HTML in a year</h1>
<p>
<blink><b>Hello friends!</b></blink>
</p>
<p>
The Serenity operating system turns 1 year old today. I'm counting
from the <a href="https://github.com/SerenityOS/serenity/commit/5a300551574451fbf509685d11095bda4fcb20be">first commit</a> in the
<a href="https://github.com/SerenityOS/serenity/">git repository</a>,
on October 10, 2018.
Parts of the code had been around for a while before that, so this
first commit was really about putting everything I was tinkering
with into a shared repo.
</p>
<p>Anyways... we have to start somewhere!</p>
<p>
<b>NOTE:</b> This web page is very light on HTML/CSS features so that it
can be rendered by Serenity's own Browser!
</p>
<p>
In the beginning there were four components:
</p>
<ul>
<li>The AK utility library</li>
<li>An ELF executable loader</li>
<li>An ext2 filesystem parser</li>
<li>A simple GUI toolkit on top of SDL</li>
</ul>
<p>
These were just some little C++ projects I had been tinkering with
after installing Slackware 11 on an old PC to do some hacking.
None of them were very mature, but it was fun, and I was in a place
where I needed to do some programming to find myself again.
</p>
<p>
Here's how the ext2 filesystem parser looked like when running:
</p>
<pre>
::>cd /home/andreas
::>ls -l
[VFS] ls ///home/andreas -> ext2fs 01:00000017
01:00000017 drwxr-xr-x 1024 2018-10-08 13:47:04 ./
01:00000016 drwxr-xr-x 1024 2018-10-02 23:43:49 ../
01:00000018 -rw-r--r-- 18 2018-10-02 23:44:09 file1
01:00000019 -rw-r--r-- 18 2018-10-02 23:44:14 file2
::>
</pre>
<div>
<p><b>2018-10-10:</b> The first ever "screenshot" of what became Serenity:</p>
<a href="2018-10-10.png"><img src="thumb.2018-10-10.png"></a>
</div>
<p>
I imported a little x86 kernel I had been working on earlier in
the year. It was a piece of crap, but it was a place to start.
I originally had some weird idea that kernels should be written
in C, so I had tried to write in C, but I thankfully realized very
quickly that I was being silly. :^)
</p>
<div>
<p><b>2018-11-08:</b> Serenity running inside a virtual machine:</p>
<a href="2018-11-08.png"><img src="thumb.2018-11-08.png"></a>
</div>
<p>
I kept working on the GUI toolkit on my Linux system, while also
developing the standalone system. This is how far I got with the
GUI while it was still sitting on top of SDL on Linux:
</p>
<div>
<p><b>2019-01-09:</b> The "Widgets" test program in an SDL framebuffer:</p>
<a href="2019-01-09.png"><img src="thumb.2019-01-09.png"></a>
</div>
<p>
I then decided it was time to get this running on top of Serenity's
own kernel. A day later, I saw this running in a VM for the first time.
It was the most beautiful thing I had ever seen.
</p>
<div>
<p><b>2019-01-10:</b> Serenity booting into a GUI for the first time:</p>
<a href="2019-01-10.png"><img src="thumb.2019-01-10.png"></a>
</div>
<p>
I started working on a userspace API for doing GUI stuff. The original
version was a monstrosity with the window server running in the kernel
and processes making syscalls to create windows, etc.
</p>
<div>
<p><b>2019-01-21:</b> Seeing how many "guitest" processes I can spawn:</p>
<a href="2019-01-21.png"><img src="thumb.2019-01-21.png"></a>
</div>
<div>
<p><b>2019-02-03:</b> Added FontEditor and Clock, ported GNU bc:</p>
<a href="2019-02-03.png"><img src="thumb.2019-02-03.png"></a>
</div>
<div>
<p><b>2019-02-08:</b> Wallpaper support, a "top" program, and more:</p>
<a href="2019-02-08.png"><img src="thumb.2019-02-08.png"></a>
</div>
<div>
<p><b>2019-02-11:</b> First implementation of menus! And a very early FileManager:</p>
<a href="2019-02-11.png"><img src="thumb.2019-02-11.png"></a>
</div>
<div>
<p><b>2019-02-28:</b> Early version of ProcessManager (today called SystemMonitor):</p>
<a href="2019-02-28.png"><img src="thumb.2019-02-28.png"></a>
</div>
<p>
Somewhere around here I figured it would be cool to add networking support,
so I started building a network stack.
</p>
<div>
<p><b>2019-03-12:</b> My host machine is pinging me!</p>
<a href="2019-03-12.png"><img src="thumb.2019-03-12.png"></a>
</div>
<div>
<p><b>2019-03-15:</b> The first thing I did when TCP kinda worked was build an IRC client:</p>
<a href="2019-03-15.png"><img src="thumb.2019-03-15.png"></a>
</div>
<div>
<p><b>2019-03-29:</b> Using FileManager to drive development of tree and icon views:</p>
<a href="2019-03-29.png"><img src="thumb.2019-03-29.png"></a>
</div>
<div>
<p><b>2019-04-11:</b> First screenshot of VisualBuilder, a Visual Basic inspired GUI design tool:</p>
<a href="2019-04-11.png"><img src="thumb.2019-04-11.png"></a>
</div>
<div>
<p><b>2019-04-20:</b> I made a Snake game. You gotta have snake!</p>
<a href="2019-04-20.png"><img src="thumb.2019-04-20.png"></a>
</div>
<div>
<p><b>2019-04-22:</b> First semi-successful GCC port. It can only compile small C programs:</p>
<a href="2019-04-22.png"><img src="thumb.2019-04-22.png"></a>
</div>
<div>
<p><b>2019-06-14:</b> Started building PaintBrush, a simple painting application:</p>
<a href="2019-06-14.png"><img src="thumb.2019-06-14.png"></a>
</div>
<div>
<p><b>2019-07-14:</b> After the system got basic sound support, I built Piano, a desktop synthesizer:</p>
<a href="2019-07-14.png"><img src="thumb.2019-07-14.png"></a>
</div>
<div>
<p><b>2019-08-27:</b> New menu look inspired by Microsoft circa 2002:</p>
<a href="2019-08-27.png"><img src="thumb.2019-08-27.png"></a>
</div>
<div>
<p><b>2019-09-09:</b> Ladies and gentlemen, we've got DOOM:</p>
<a href="2019-09-09.png"><img src="thumb.2019-09-09.png"></a>
</div>
<div>
<p><b>2019-09-29:</b> Working on basic CSS support in LibHTML:</p>
<a href="2019-09-29.png"><img src="thumb.2019-09-29.png"></a>
</div>
<div>
<p><b>2019-10-10</b> Viewing <b>this webpage</b> in Serenity's Browser!</p>
<a href="2019-10-10.png"><img src="thumb.2019-10-10.png"></a>
</div>
<p>
And with that, this little screenshot tour of the first year of Serenity is over.
</p>
<p>
If you would like to see more, I've also been making regular monthly update videos
throughout the year:
</p>
<ul>
<li><a href="https://www.youtube.com/watch?v=hE52D-zbX3g">Serenity OS update (March 2019)</a></li>
<li><a href="https://www.youtube.com/watch?v=RBr5If8GrM4">Serenity OS update (April 2019)</a></li>
<li><a href="https://www.youtube.com/watch?v=KHpGvwBTRxM">Serenity OS update (May 2019)</a></li>
<li><a href="https://www.youtube.com/watch?v=-SQP3E67bnc">Serenity OS update (June 2019)</a></li>
<li><a href="https://www.youtube.com/watch?v=YfTAezcRPs8">Serenity OS update (July 2019)</a></li>
<li><a href="https://www.youtube.com/watch?v=h76Ah4oKfKE">Serenity OS update (August 2019)</a></li>
<li><a href="https://www.youtube.com/watch?v=vK0h_Ih4dw4">Serenity OS update (September 2019)</a></li>
</ul>
<p>
To all the boys and girls who have helped out in the last year, with code, bug reports,
docs, commenting on videos, e-mailing, hanging out on IRC, retweeting, telling your friends, etc,
thank you! I'm so grateful for all the love this project has been getting.
</p>
<p>
And also, a huge <b>thank you!</b> to everyone who has supported me via
<a href="https://patreon.com/serenityos">Patreon</a>
and other donation methods! It's my dream to turn this into a full time show some day,
and you're a huge part of keeping that dream alive. :)
</p>
<p>
Let's see what we can do in year 2!
</p>
<p>
<i>Andreas Kling, 2019-10-10</i>
</p>
<p>
<a href="https://github.com/awesomekling">GitHub</a> |
<a href="https://youtube.com/c/AndreasKling">YouTube</a> |
<a href="https://twitter.com/awesomekling">Twitter</a> |
<a href="https://patreon.com/serenityos">Patreon</a> |
<a href="https://paypal.me/awesomekling">PayPal</a>
</p>
</body>
</html>
|
SerenityOS: From zero to HTML in a year
# SerenityOS: From zero to HTML in a year
**Hello friends!**
The Serenity operating system turns 1 year old today. I'm counting
from the [first commit](https://github.com/SerenityOS/serenity/commit/5a300551574451fbf509685d11095bda4fcb20be) in the
[git repository](https://github.com/SerenityOS/serenity/),
on October 10, 2018.
Parts of the code had been around for a while before that, so this
first commit was really about putting everything I was tinkering
with into a shared repo.
Anyways... we have to start somewhere!
**NOTE:** This web page is very light on HTML/CSS features so that it
can be rendered by Serenity's own Browser!
In the beginning there were four components:
* The AK utility library
* An ELF executable loader
* An ext2 filesystem parser
* A simple GUI toolkit on top of SDL
These were just some little C++ projects I had been tinkering with
after installing Slackware 11 on an old PC to do some hacking.
None of them were very mature, but it was fun, and I was in a place
where I needed to do some programming to find myself again.
Here's how the ext2 filesystem parser looked like when running:
```
::>cd /home/andreas
::>ls -l
[VFS] ls ///home/andreas -> ext2fs 01:00000017
01:00000017 drwxr-xr-x 1024 2018-10-08 13:47:04 ./
01:00000016 drwxr-xr-x 1024 2018-10-02 23:43:49 ../
01:00000018 -rw-r--r-- 18 2018-10-02 23:44:09 file1
01:00000019 -rw-r--r-- 18 2018-10-02 23:44:14 file2
::>
```
**2018-10-10:** The first ever "screenshot" of what became Serenity:
[![](thumb.2018-10-10.png)](2018-10-10.png)
I imported a little x86 kernel I had been working on earlier in
the year. It was a piece of crap, but it was a place to start.
I originally had some weird idea that kernels should be written
in C, so I had tried to write in C, but I thankfully realized very
quickly that I was being silly. :^)
**2018-11-08:** Serenity running inside a virtual machine:
[![](thumb.2018-11-08.png)](2018-11-08.png)
I kept working on the GUI toolkit on my Linux system, while also
developing the standalone system. This is how far I got with the
GUI while it was still sitting on top of SDL on Linux:
**2019-01-09:** The "Widgets" test program in an SDL framebuffer:
[![](thumb.2019-01-09.png)](2019-01-09.png)
I then decided it was time to get this running on top of Serenity's
own kernel. A day later, I saw this running in a VM for the first time.
It was the most beautiful thing I had ever seen.
**2019-01-10:** Serenity booting into a GUI for the first time:
[![](thumb.2019-01-10.png)](2019-01-10.png)
I started working on a userspace API for doing GUI stuff. The original
version was a monstrosity with the window server running in the kernel
and processes making syscalls to create windows, etc.
**2019-01-21:** Seeing how many "guitest" processes I can spawn:
[![](thumb.2019-01-21.png)](2019-01-21.png)
**2019-02-03:** Added FontEditor and Clock, ported GNU bc:
[![](thumb.2019-02-03.png)](2019-02-03.png)
**2019-02-08:** Wallpaper support, a "top" program, and more:
[![](thumb.2019-02-08.png)](2019-02-08.png)
**2019-02-11:** First implementation of menus! And a very early FileManager:
[![](thumb.2019-02-11.png)](2019-02-11.png)
**2019-02-28:** Early version of ProcessManager (today called SystemMonitor):
[![](thumb.2019-02-28.png)](2019-02-28.png)
Somewhere around here I figured it would be cool to add networking support,
so I started building a network stack.
**2019-03-12:** My host machine is pinging me!
[![](thumb.2019-03-12.png)](2019-03-12.png)
**2019-03-15:** The first thing I did when TCP kinda worked was build an IRC client:
[![](thumb.2019-03-15.png)](2019-03-15.png)
**2019-03-29:** Using FileManager to drive development of tree and icon views:
[![](thumb.2019-03-29.png)](2019-03-29.png)
**2019-04-11:** First screenshot of VisualBuilder, a Visual Basic inspired GUI design tool:
[![](thumb.2019-04-11.png)](2019-04-11.png)
**2019-04-20:** I made a Snake game. You gotta have snake!
[![](thumb.2019-04-20.png)](2019-04-20.png)
**2019-04-22:** First semi-successful GCC port. It can only compile small C programs:
[![](thumb.2019-04-22.png)](2019-04-22.png)
**2019-06-14:** Started building PaintBrush, a simple painting application:
[![](thumb.2019-06-14.png)](2019-06-14.png)
**2019-07-14:** After the system got basic sound support, I built Piano, a desktop synthesizer:
[![](thumb.2019-07-14.png)](2019-07-14.png)
**2019-08-27:** New menu look inspired by Microsoft circa 2002:
[![](thumb.2019-08-27.png)](2019-08-27.png)
**2019-09-09:** Ladies and gentlemen, we've got DOOM:
[![](thumb.2019-09-09.png)](2019-09-09.png)
**2019-09-29:** Working on basic CSS support in LibHTML:
[![](thumb.2019-09-29.png)](2019-09-29.png)
**2019-10-10** Viewing **this webpage** in Serenity's Browser!
[![](thumb.2019-10-10.png)](2019-10-10.png)
And with that, this little screenshot tour of the first year of Serenity is over.
If you would like to see more, I've also been making regular monthly update videos
throughout the year:
* [Serenity OS update (March 2019)](https://www.youtube.com/watch?v=hE52D-zbX3g)
* [Serenity OS update (April 2019)](https://www.youtube.com/watch?v=RBr5If8GrM4)
* [Serenity OS update (May 2019)](https://www.youtube.com/watch?v=KHpGvwBTRxM)
* [Serenity OS update (June 2019)](https://www.youtube.com/watch?v=-SQP3E67bnc)
* [Serenity OS update (July 2019)](https://www.youtube.com/watch?v=YfTAezcRPs8)
* [Serenity OS update (August 2019)](https://www.youtube.com/watch?v=h76Ah4oKfKE)
* [Serenity OS update (September 2019)](https://www.youtube.com/watch?v=vK0h_Ih4dw4)
To all the boys and girls who have helped out in the last year, with code, bug reports,
docs, commenting on videos, e-mailing, hanging out on IRC, retweeting, telling your friends, etc,
thank you! I'm so grateful for all the love this project has been getting.
And also, a huge **thank you!** to everyone who has supported me via
[Patreon](https://patreon.com/serenityos)
and other donation methods! It's my dream to turn this into a full time show some day,
and you're a huge part of keeping that dream alive. :)
Let's see what we can do in year 2!
*Andreas Kling, 2019-10-10*
[GitHub](https://github.com/awesomekling) |
[YouTube](https://youtube.com/c/AndreasKling) |
[Twitter](https://twitter.com/awesomekling) |
[Patreon](https://patreon.com/serenityos) |
[PayPal](https://paypal.me/awesomekling)
| https://www.serenityos.org/happy/1st/ |
<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN">
<HTML>
<HEAD>
<TITLE>Mad Martian - Fun with Jell-O</TITLE>
<meta http-equiv="Content-Style-Type" content="text/css">
<STYLE type="text/css">
<!--
TABLE {
font-size : 8pt;
margin-left:0pt;}
body {margin:0pt;
font-family:arial,sans-serif;}
A.menu { text-decoration: none; }
A.menu:link { color: black; }
A.menu:visited { color: black; }
A.menu:hover { color: white; background:darkblue; }
A.menu:active { color: white; background:darkblue; }
a:link {color:aqua;background:none}
a:visited {color:aqua;background:none}
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<div align="center"><font size=6 color=red>Fun with Jell-O!</FONT>
</div>
<font size=5><strong>Jell-O-Rama!</strong><BR></font>
Every April Fools in Eugene, Oregon there is a rather unusual tribute to the most famous gelled substance. "Jell-O-Rama", aka the Jell-O Art Show, is held at the Maude Kerns Art Gallery and features works by local artists using Jell-O as a medium. Here are some examples from the past few years of Jell-O-Rama.<BR><BR>
Click on a small photo to see a big one!<BR>
<BR>
Here is the Mad Martian 1996 Jell-O-Rama entry, "It Came From The Fountain Pool." Ken is mauled by an evil monster as Barbie waves to her fans! The water and guts are all made of Jell-O. Barbie's bikini was particularly popular.<BR>
<A HREF="images/food/jello1.jpg" target="food"><IMG SRC="images/food/jello1s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<A HREF="images/food/jello2.jpg" target="food"><IMG SRC="images/food/jello2s.jpg" alt="" WIDTH=48 HEIGHT=64></A>
<A HREF="images/food/jello3.jpg" target="food"><IMG SRC="images/food/jello3s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<A HREF="images/food/jello4.jpg" target="food"><IMG SRC="images/food/jello4s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<BR CLEAR=all>
<br>
Here are some more 1996 Jell-O-Rama entries:<BR>
<A HREF="images/food/jello5.jpg" target="food"><IMG SRC="images/food/jello5s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<A HREF="images/food/jello6.jpg" target="food"><IMG SRC="images/food/jello6s.jpg" alt="" WIDTH=48 HEIGHT=64></A>
<A HREF="images/food/jello7.jpg" target="food"><IMG SRC="images/food/jello7s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<BR CLEAR=all>
<br>
Jell-O-Rama 1995<BR>
<A HREF="images/food/jello11.jpg" target="food"><IMG SRC="images/food/jello11s.jpg" alt="" WIDTH=48 HEIGHT=64></A>
<A HREF="images/food/jello12.jpg" target="food"><IMG SRC="images/food/jello12s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<A HREF="images/food/jello13.jpg" target="food"><IMG SRC="images/food/jello13s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<A HREF="images/food/jello14.jpg" target="food"><IMG SRC="images/food/jello14s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<A HREF="images/food/jello15.jpg" target="food"><IMG SRC="images/food/jello15s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<A HREF="images/food/jello16.jpg" target="food"><IMG SRC="images/food/jello16s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<BR CLEAR=all>
My improved recipe for Jell-O Brains: Instead of cold water, simply use vanilla ice cream! It tastes much better than the sweetened condensed milk the original Brain recipe calls for. I also prefer the PEACH Jell-O for both color and flavor. Don't forget to add 4 drops of green food coloring!<br>
<br>
Jell-O-Rama 1994<BR>
<A HREF="images/food/jello8.jpg" target="food"><IMG SRC="images/food/jello8s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<A HREF="images/food/jello9.jpg" target="food"><IMG SRC="images/food/jello9s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<A HREF="images/food/jello10.jpg" target="food"><IMG SRC="images/food/jello10s.jpg" alt="" WIDTH=64 HEIGHT=48></A>
<BR CLEAR=all>
<br>
<font size=2>If you wait, you will hear a brief excerpt from "Green Jell-O Theme Song" by Green Jelly.</font><br>
<BR>
<P style="color:teal;font-size:10pt;font-weight:bold;margin-top:0;margin-bottom:0">Copyright © 1995-2018 Mad Martian® All Rights Reserved.</p>
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Fun with Jell-O!
**Jell-O-Rama!**
Every April Fools in Eugene, Oregon there is a rather unusual tribute to the most famous gelled substance. "Jell-O-Rama", aka the Jell-O Art Show, is held at the Maude Kerns Art Gallery and features works by local artists using Jell-O as a medium. Here are some examples from the past few years of Jell-O-Rama.
Click on a small photo to see a big one!
Here is the Mad Martian 1996 Jell-O-Rama entry, "It Came From The Fountain Pool." Ken is mauled by an evil monster as Barbie waves to her fans! The water and guts are all made of Jell-O. Barbie's bikini was particularly popular.
[![](images/food/jello1s.jpg)](images/food/jello1.jpg)
[![](images/food/jello2s.jpg)](images/food/jello2.jpg)
[![](images/food/jello3s.jpg)](images/food/jello3.jpg)
[![](images/food/jello4s.jpg)](images/food/jello4.jpg)
Here are some more 1996 Jell-O-Rama entries:
[![](images/food/jello5s.jpg)](images/food/jello5.jpg)
[![](images/food/jello6s.jpg)](images/food/jello6.jpg)
[![](images/food/jello7s.jpg)](images/food/jello7.jpg)
Jell-O-Rama 1995
[![](images/food/jello11s.jpg)](images/food/jello11.jpg)
[![](images/food/jello12s.jpg)](images/food/jello12.jpg)
[![](images/food/jello13s.jpg)](images/food/jello13.jpg)
[![](images/food/jello14s.jpg)](images/food/jello14.jpg)
[![](images/food/jello15s.jpg)](images/food/jello15.jpg)
[![](images/food/jello16s.jpg)](images/food/jello16.jpg)
My improved recipe for Jell-O Brains: Instead of cold water, simply use vanilla ice cream! It tastes much better than the sweetened condensed milk the original Brain recipe calls for. I also prefer the PEACH Jell-O for both color and flavor. Don't forget to add 4 drops of green food coloring!
Jell-O-Rama 1994
[![](images/food/jello8s.jpg)](images/food/jello8.jpg)
[![](images/food/jello9s.jpg)](images/food/jello9.jpg)
[![](images/food/jello10s.jpg)](images/food/jello10.jpg)
If you wait, you will hear a brief excerpt from "Green Jell-O Theme Song" by Green Jelly.
Copyright © 1995-2018 Mad Martian® All Rights Reserved.
| https://madmartian.com/food_jello.htm |
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# Ships of the Terran Empire Universe
### Shown below are pictures captured using Star Trek: Bridge Commander, Starfleet Command: Orion Pirates and assorted mods for each
## Terran Empire Starfleet
[![Terran Empire Starfleet](http://happytarget.50megs.com/janes/TEcrest.jpg)](http://happytarget.50megs.com/TE.html)
## Klingon Fleet
[![Klingon Fleet](http://happytarget.50megs.com/Klingon.JPG)](http://happytarget.50megs.com/Klingon.html)
## Cardassian Fleet
[![Cardassian Fleet](http://happytarget.50megs.com/Card.jpg)](http://happytarget.50megs.com/Card.html)
## Lyran Fleet
[![Lyran Fleet](http://happytarget.50megs.com/Lyran.jpg)](http://happytarget.50megs.com/Lyran.html)
## Mirak Fleet
[![Mirak Fleet](http://happytarget.50megs.com/Mirak.jpg)](http://happytarget.50megs.com/Mirak.html)
## Interstellar Concordium Fleet
[![Interstellar Concordium Fleet](http://happytarget.50megs.com/ISC.jpg)](http://happytarget.50megs.com/ISC.html)
## Gorn Fleet
[![Gorn Fleet](http://happytarget.50megs.com/Gorn.jpg)](http://happytarget.50megs.com/Gorn.html)
## Hydran Fleet
[![Hydran Fleet](http://happytarget.50megs.com/Hydran.jpg)](http://happytarget.50megs.com/Hydran.html)
## Romulan Fleet
[![Romulan Fleet](http://happytarget.50megs.com/Rom.jpg)](http://happytarget.50megs.com/Romulan.html)
## Orion Pirate Fleet
[![Orion Pirate Fleet](http://happytarget.50megs.com/Orion.jpg)](http://happytarget.50megs.com/Orion.html)
## Species 8472
[![Battleship Class Pictures](http://happytarget.50megs.com/buttonbattleship.jpg)](http://happytarget.50megs.com/battleship.html)
## Species 8472 vs 2nd Fleet
[![Battle Pictures](http://happytarget.50megs.com/buttonbattles8472secondfleet.jpg)](http://happytarget.50megs.com/8472vs2ndfleet.html)
## The Fleet Universe
[The Fleet](http://happytarget.50megs.com/thefleet.html)
## Terran Empire Starfleet Uniforms
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<p align="center"><a href="mailto:ctrymaus@gmail.com">
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<p align="center"><strong>This site copyright
1997-2018 by Joanna M. Phillips</strong></p>
<p align="center"><strong>Last update: February 16, 2018</strong></p>
<p align="center"> </p>
<hr color="#800080" width="75%">
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<div align="center">
<table border="0" width="95%" cellspacing="1">
<tr>
<td align="center">
<p align="center"><strong><font size="2">Background by Infinite Fish
| Animated danglers from Wings of Love and Light | Some artwork on
this page by Vikimouse | Baked goods from SweetRoom | Pink house and
tree from Country Colors | Quilt square icon from Susannes Grafik |
Gel pens photograph copyright © 2002-2015 Joanna M. Phillips |
Zodiac graphic by CountryMouse | Globe by Luvdalot Graphics</font></strong></td>
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The Mouse House
A:hover {color: #FF0000; text-decoration: overline underline; font-weight: bold}
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|
The Mouse House
---
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| | CountryMouse, writing letters! | |
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<!DOCTYPE html>
<html>
<img src="https://cdn.discordapp.com/attachments/626054197325856768/950440039790309526/website_banner.png" height="200" width="800">
<h1> Welcome to my website. I am an analog media enthusiast <br>
and love to share in my hobbies with anyone else interested.</h1>
<h3> I try to archive any VHS tapes that I find. I upload them to my youtube channel as long as I am<br>
relatively confident they won't get taken down or copyrighted.</h3>
<p> <a href="https://youtube.com/channel/UC9mP0LIjBangrnFuNJDuvAw">Watch my youtube videos here!</a></p>
<p> <a href="https://vhs-jess.creator-spring.com/">Here is my Teespring with designs by myself and Kaz!</a></p>
<h3> If you wish to contact me, you can email me at vhsjessie@gmail.com </h3>
<h4> Now, onto the blog!</h4>
<!-- for some reason the website's function detection doesn't like kirby, ignore. -->
<img src="https://media.discordapp.net/attachments/916115136631152790/990997441270648862/got_internet.png" height="300" width="300">
<h1>The Wonderful World of Windows 98! (is janky)</h1>
<h3>August 22nd, 2022</h3>
<h3> [Forgot to take good pictures for the post but I'll update them here later]</h3>
<h3>Last year I picked up an old Y2K era Windows 98 pc from FB marketplace. I <br>
played around with it a bit, reading some ancient emails left on the disk,<br>
and seeing what had been installed on it. It was a nice novelty and it came<br>
with some cool peripherals and a neat little 800x600 monitor, but I never <br>
really made much use of it. That was, until a few months back I decided that <br>
I wanted to build it into a games/media creation pc. I'm not very familiar <br>
with pc hardware from that era, but an AMD k6 seems half decent, and a M571<br>
motherboard seemed to have a good rep online from what I could find in a few<br>
minutes of research. So I set out to get it setup to a usable state in 2022.</h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/1011331510529441802/IMG_20220730_163805.jpg?width=450&height=600"><br>
<h3> The first thing I had to do, was replace the broken CD drive. The one<br>
in the computer would not eject, and I had no way to get any files INTO the <br>
computer. I managed to track down an IDE dvd burner pretty easily, and got <br>
it installed no problem. After playing around with some of the goofy programs<br>
and clip art collection CDs I also picked up, I decided that if I was going<br>
to be using the computer with any kind of regularity, I was going to need <br>
a better way of transferring files than burning CDs every time.<br>
<br>
I started watching some videos about Windows 98 and USB storage, and was <br>
surprised that the OS could do it. (In my mind, burning CDs with win 98 <br>
seemed like an impressive thing, but then again I'm not *that* old.)<br>
So I went online and found a cheap PCI card that had a number of USB ports<br>
I could use for transferring files and got it ordered.</h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/1011328903748526100/IMG_20220730_170035.jpg?width=600&height=500">
<h5>I played around with some of the art program CDs I had in the meantime</h5>
<h3>While I was figuring out all the USB stuff and ordering the PCI card, I was<br>
also working on upgrading the OS to 98SE. The operating system that came on <br>
the computer was 98 First Edition. I had learned that SE is really what you<br>
want to run, so I made the great mistake of trying to install a new OS with<br>
no clue what I was doing. I only realized after I had gone through the install<br>
that I had no drivers for the motherboard, and that if I wanted to use any <br>
graphics programs, I was going to need VGA drivers, and Sound drivers if I <br>
wanted to hear anything either. I had no idea what to do and ended up fumbling<br>
around with drivers programs, bricking the install, and reinstalling the OS<br>
about a dozen times until found a website hosting all the drivers I needed.<br>
<br>
Once I had done one more install of 98SE, I installed the motherboard's drivers<br>
and learned that when you install an operating system that many times over,<br>
it doesn't delete everything and will leave files left over. Oh how pampered<br>
I've been by windows 7 and onward, deleting everything when you do a fresh<br>
install! How naieve I was filling up the Master Boot Record of the hard disk<br>
with a bunch of trash and broken files! Now I sit with a computer that won't<br>
function outside of safe mode because so many files are busted.<br>
<br>
Currently I am investigating boot disks to clear the Master Boot Record and<br>
completely wipe the drive. I am still not very knowledgeable about this stuff<br>
but I'm going to take my time and make sure that I do it as right as possible<br>
this time!</h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/1011322099064913920/GOOD_TIME_MYRTLE.png" height="300" width="300" usemap="#myrtle">
<map name="myrtle">
<area shape="circle" coords="150,150,90" href="https://youtu.be/ZKwiJig6Dlg">
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<h1> Dumpster Diving at a Hospital (LEGALLY, I PROMISE)</h1>
<h3> July 25thth, 2022</h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/1001122577646895265/unknown.png" height="500" width="600">
<h5> A friend of a friend found these TVs at the dumpster area of a local hospital.</h5>
<h3> A friend of mine saw this image on their snapchat and made me aware of this lovely<br>
little pile of TVs sitting behind a local hospital. After work that day I stopped <br>
by the back loading bay and got to work checking these little guys over. Most of <br>
them were in decent condition, with only a couple of them being significantly <br>
scratched and scraped on the front tube. I haven't yet measured their screen<br>
sizes but I'd guess they're somewhere between 12 and 14" in size. Perfect size<br>
to load up four of them in my tiny car and bring them home with me.</h3><br>
<img src="https://cdn.discordapp.com/attachments/626054197325856768/1001119738044358666/IMG_20220722_172538.jpg" height="400" width="500">
<h5> The four TVs I deemed in good enough condition to bring home, with a copy of my VHS mixtape for scale.</h5>
<h3> The TVs are a great size and just add to the already too-big collection of small<br>
form factor CRTs I own, but they were free so who cares :). The TVs themselves are pretty<br>
interesting and have some weird features since they were used inside a hospital.<br></h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/1001127809936281700/unknown.png" height="400" width="400">
<h5> The 1/4 inch audio out and the toggle switch on the side of the three PDi brand TVs.</h5>
<h3> On the side of the three smaller ones, there is a 1/4 inch jack, and a <br>
toggle switch. After opening the TV up, the circuitboard inside has <br>
"Pillow Speaker Board" printed on the PCB for a pillow containing<br>
speakers so the audio from the TV doesn't disturb other people in the<br>
hospital. The internals of this TV are also very non-standard. The board<br>
that has that 1/4 inch jack and switch also has the TV's power cable <br>
routed through it. I haven't seen it before in any of my other TVs.</h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/1001129483060903956/unknown.png" height="400" width="500">
<h5> The Pillow Speaker Board fastened to the inside of the back shell of the TV.</h5>
<h3> The one larger of the four TVs is a Zenith brand tv, and has an interesting<br>
difference from the other three PDi branded models. It has a 5 pin dinn connector<br>
on the back. It does also have a toggle switch, but no 1/4 inch audio out. I think<br>
that the 5 pin connector may be for audio? I may be for something else as it was<br>
the only TV of the lot that wasn't a little PDi brand one, so it may not have <br>
been used for a patient TV.</h3>
<img src="https://cdn.discordapp.com/attachments/626054197325856768/1001119740426735657/IMG_20220722_170746.jpg" height="400" width="550">
<h5> The 5 pin dinn connector on the back of the Zenith.</h5>
<h3> The Zenith TV has great color but will need some picture adjustment, and<br>
without a remote to access any kind of service menu, I'll have to open it up<br>
and use the manual adjustment pots on the mainboard. I've never done that before<br>
and I'm very excited to try it. Hopefully I can get the picture looking good and <br>
sized properly because its in great condition and a great size little TV.</h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/1001131953619206215/TRUE_TRANQUILITY.png" height="300" width="300" usemap="#rat">
<map name="rat">
<area shape="circle" coords="200,260,40" href="https://youtu.be/Z_qdhpYTtQQ?t=458">
</map>
<h1> Imagine a VHS mixtape in 2022</h1>
<h3> June 13th, 2022</h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/985967515878432848/IMG_20220610_155252.jpg" height="591" width="787">
<h5> My first ever VHS mixtape! I am very proud of it! :D Cover art done by my boyfriend Kaz!</h5>
<h6>------------------------------------------------------------------------------------------------------</h6>
<h3>Over the last few years I've been collecting all kinds of weird and goofy VHS tapes<br>
from thrift stores around me. A few months ago, I decided that instead of taking a <br>
handful of tapes to show friends whatever weird content I had discovered, that I would <br>
instead edit a lot of similarly themed tapes together into my own tape and add a bit <br>
of my own editing to make something special! The tape is named "Lifestyles" and has a <br>
lot of videos on tourism, vacationing, home living, and some other little odds and ends <br>
edited together to make a delightful little "get-away" experience.<br>
<br>
It was extremely fun getting to create my own intro, get my friends to help me make<br>
transition audio between tapes, and to add my own little flairs and funny edits. <br>
I really think I made something that adds to the experience of watching the videos<br>
and I can't wait to work on the next idea I have for a mixtape! Lifestyles should<br>
be publicly viewable on my youtube after I'm done stroking my ego hosting watch<br>
parties, but I'm putting the link here as a thank you for reading my website!<br>
<br>
You can watch my VHS mixtape "Lifestyles"<a href="https://youtu.be/n6EdRLtKIV8">HERE</a><br>
I plan on making a very small amount of physical copies to hand out to friends<br>
and I am enjoying producing physical copies almost as much as editing the video itself!<br>
Making something tangible that you can physically hold and point at and say "Hey,<br>
I made this!" Is such a satisfying feeling and something I really missed.<br> </h3>
<img src="https://media.discordapp.net/attachments/916115136631152790/992055738887315497/whole_new_world.png" height="300" width="300">
<h1> A New Beast Enters The Ring!</h1>
<h3> April 4th, 2022</h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/960534787733454858/IMG_20220318_212541.jpg" height="591" width="787">
<h5> My recently picked up JVC AV-27D305. A high quality 27" Set. Very happy with it!</h5>
<h6>------------------------------------------------------------------------------------------------------</h6>
<h3> Last week I picked up this nice JVC AV-27D305. I had been looking for a nice <br>
"Living room size" set for a while, and when I came across this for sale I jumped on it<br>
immediately. The JVC D-series is very well known for its quality. From what I can tell, <br>
its regarded about as highly as Sony Trinitrons, if not just behind. I can certainly <br>
vouch for its quality after playing a few games and watching a few VHS tapes, but I have<br>
not experienced a Sony Trinitron larger than 14" that isn't a computer monitor. I imagine <br>
its quality wouldn't leave much to be desired though, as even watching movies over Composite <br>
looks fantastic!<br>
<br></h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/960534787116924938/IMG_20220328_081826.jpg" height="591" width="787">
<h5> My living room is a mess after making space for it where my old beater flat screen used to be.</h5>
<h6>------------------------------------------------------------------------------------------------------</h6>
<h3>I don't use my living room too often for watching old media, usually thats done at my desk<br>
where I'm capturing footage for my <a href="https://youtube.com/channel/UC9mP0LIjBangrnFuNJDuvAw">Youtube Channel</a>. I think I will be enjoying my living<br>
room quite a bit more now with this beautiful piece of equipment! I really love the nice<br>
silver plastic and aesthetic of the mid 00's. I am hugely nostalgic for that time in my <br>
life and to have something like this in my home, to be able to come home and put on <br>
my favorite shows from that era, or play some PS2 games on my nice silver slim model, <br>
I couldn't be happier with this pickup!<br>
<br>
One of the biggest reasons I picked up this model was for the Component video connection.<br>
I haven't owned a consumer CRT with component video before, and I really wanted to see <br>
how big of a difference it makes when playing era-appropriate games. I bought a cable <br>
and some female-female connectors so I don't have to get my hands back there every time<br>
I want to switch consoles. I've tried a few games on it so far; God Hand(PS2), Kinetica(PS2), <br>
FZERO GX (Wii component), LSD Dream Emulator (PS1), and they all look absolutely<br>
fantastic! I've played all those games on a 1600x1200 Sony Trinitron PC monitor with the<br>
consoles being fed through a video upscaler and converter (see post from March 7th), but to play<br>
them on a TV with those connections just gives it that quality I remember from the time. <br>
<br>
Between a matching silver PS2 for games and DVD playback, a nice Samsung VCR for tapes, <br>
and any video game consoles I can get my hands on, my living room is looking nearly<br>
complete as far as media consumption goes.</h3>
<br>
<img src="https://media.discordapp.net/attachments/916115136631152790/992055738526613504/refreshment.png" height="300" width="300">
<br>
<h1> Fantastic Plastic, Hello Yellow!</h1>
<h3> March 17th, 2022</h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/954011604809293894/IMG_20220219_182439__01.jpg" height="375" width="787">
<h5> My daily driver, a Cherry G-80 1800 keyboard. Age has yellowed this ABS plastic to heck, but I love it.</h5>
<h6>------------------------------------------------------------------------------------------------------</h6>
<h3> Last summer I picked up four of these Cherry G-80 1800 keyboards from a dying Sears<br>
while I was on a little road trip. Having been into custom keyboards for some time before <br>
this trip, I was stunned when I found four of these boards sitting in a bin. If anyone else<br>
had walked into that Sears who knew about these boards, they would have gotten snagged <br>
immediately. I also picked up a small monochrome CRT security monitor, but that will <br>
probably receive its own post here sometime.<br>
<br>
All four of the boards used Cherry's "MY" switch (pronounced "M - Why") , which have zero<br>
value in this dayand age. Fortunately for me though, two of the boards had Cherry's old ABS<br>
plastic keycaps. These are quite high quality keycaps and I was ecstatic to find two sets <br>
of these! The other two had Lasered PBT plastic caps which are noticably lower quality than<br>
the doubleshot ABS plastic but still perfectly functional. All four sets are Cherry profile,<br>
which is my favorite keycap profile to type on so I am quite happy with that.<br>
<br>
All four boards also came with a very large amount of "Re-legendable" keycaps. These caps<br>
have a beige plastic base, with a clear plastic top-cap that snaps on. You can create your<br>
own legends, print them or write them onto paper, and then insert them into these caps and<br>
create your own key legends. These caps are a very cool novelty to have, but turn into a<br>
genuinely useful feature paired with the replacement internals I fitted these boards with.<br>
<br></h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/954017390407077898/IMG_20220317_100353__01.jpg" height="265" width="400">
<h5> Re-legendable keycaps on a work keyboard.</h5>
<h6>------------------------------------------------------------------------------------------------------</h6>
<h3> I replaced the original PCB and switches inside the keyboard with updated and more <br>
feature-rich internals that bring these keyboards up to 2020 spec. I used a drop-in PCB <br>
that has VIA compatibility for full programmability, as well as modern Cherry MX switches<br>
to keep it as "still Cherry" as possible. These keyboards can be programmed any-which-way<br>
I could ever want, something far more useful than modern "gamer" keyboards. The switches <br>
I used were Cherry MX Hyperglide Blacks, which are a bit stiffer-springed than the usual <br>
keyboard switches you find nowadays. I enjoy the heavier weight, and after roughly 8-months<br>
of regular use, they have become quite smooth as the plastics inside rub eachother smooth.<br>
<br>
I used to be really into custom boards before I found these, but that interest has been sated.<br>
The aesthetics of the yellowed plastic, functionality, and feel really are the best I've used.</h3>
<br>
<img src="https://media.discordapp.net/attachments/916115136631152790/991729004337975378/hot_and_fresh.png" height="300" width="300">
<br>
<h1> Crouching Tiger, Hidden Gems</h1>
<h3> March 14th, 2022 </h3>
<img src="https://media.discordapp.net/attachments/626054197325856768/952927415477354536/IMG_20220310_192444.jpg" height="500" width="370">
<h5> A two-pack of 70s kung-fu movies I found at my local thrift store over the weekend.</h5>
<h6>------------------------------------------------------------------------------------------------------</h6>
<h3> Over the weekend I stopped by my usual haunt and dug through whatever new tapes I<br>
could find. I scooped up an absolute gem of a double pack! I watched the first movie in<br>
the pack, Shaolin Deadly Kicks, and it has got to be one of my favorite full length movies<br>
I have on tape. Its rediculous, stupid, fast paced, goofy as all hell, and there was roughly<br>
only about 10 minutes of slow pacing in its 1.5 hour runtime. The movie itself is a reprint,<br>
the original having released in 1977. I had been wanting at least one movie like this for <br>
some time, but now I have two and I couldn't be happier! I'm extremely excited to watch <br>
the second movie in the pack and will give my impressions on it here whenever I do.</h3><br>
<img src="https://media.discordapp.net/attachments/626054197325856768/952927532892700712/Snapchat-528224235__01.jpg" height="500" width="370">
<h5> A DVD copy of The Texas Chainsaw Massacre 2 I also found at my local thrift purely by accident.</h5>
<h6>------------------------------------------------------------------------------------------------------</h6>
<h3> While I was thrifting, I took a quick glance at their DVD selection on the off chance <br>
there was anything weird, and within the pile of early 2000s junk, I just happen to spy this<br>
sitting on the back of one shelf. I genuinely couldn't believe it when I pulled it off the<br>
shelf, but I am so glad I decided to look through the DVDs that day! The first two Texas Chainsaw<br>
movies are some of my favorite slasher movies outside the Friday the 13th series, and finding<br>
at least one of them physically is so cool. I don't know if the DVD actually works, as its a <br>
used disc and I haven't checked it yet, but if its broken at least it'll look nice on a shelf.</h3>
<br>
<img src="https://media.discordapp.net/attachments/916115136631152790/990997441497157662/congrats_youve_won.png" height="300" width="300">
<br>
<h1>Top of the Line Computing</h1>
<h3> March 7th, 2022 </h3>
<img src="https://cdn.discordapp.com/attachments/626054197325856768/950445705082863616/IMG_20220218_222256.jpg" height="400" width="500">
<h5>Dell E771P (left) and Sony Trinitron GDM-500PS (right). The size difference here is absolutely incredible. <br>
The weight is also incredible (but not for my back) with the Sony monitor coming in at 79 pounds according to the service manual.</h5>
<h6>------------------------------------------------------------------------------------------------------</h6>
<h3>
I picked up a Sony Trinitron GDM-500PS computer monitor two weeks ago <br>
and have been slowly working it into my home desk setup. It has two inputs.<br>
One VGA port and BNC connectors for RGBHV. I didn't know anything<br>
about RGBHV and was hoping I could just get some BNC to RCA adapters<br>
and plug component video into it, but turns out its just a broken out form<br>
of VGA, as far as I can tell. I have a cheap Displayport to VGA adapter that<br>
works fine for now, but it cannot hit the monitor's maximum of 1600x1200 at 85hz.<br>
I will have to get a different adapter for that, but I am very excited to see how that<br>
looks in the future. The only video game console I own that will connect to the<br>
moitor without converters is the Dreamcast, which looks absolutely stunning.<br>
I ordered an Open Source Scan Converter to take component video and upscale<br>
it and convert it to display on the monitor, and let me tell you, I've never seen a<br>
crt display look this incredible. My childhood was playing ps2 games through<br>
composite video on a mid-range consumer CRT television, and this completely<br>
blows that into another dimension.
<br>
<br>
It was confusing trying to adjust the color settings on this unit. I bought it<br>
from a guy who has been doing computer graphics professionally since the late 90s<br>
and he must have had it in some kind of strange lighting environment because it<br>
was so dim and red-biased when I got it. It took a few days of adjustments to get<br>
it looking decent, and then another week on top of that to really figure out how <br>
to get the color settings optimal for my environment and use-case. Now that I have<br>
it setup how I want I am enjoying this behemoth of a monitor! I use it to play <br>
games, watch 4:3 aspect ratio video, and use it as a recording preview when I'm <br>
archiving VHS tapes. I'm really glad I found this thing on facebook marketplace <br>
because these are getting pretty dang rare and this one is in excellent condition.<br>
It should last me probably about as long as I'm interested in CRT displays, and I<br>
am excited to have it on my desk.</h3><br>
<img src="https://cdn.discordapp.com/attachments/626054197325856768/950445704436932638/IMG_20220218_222748.jpg" height="400" width="500"><br>
<h5> Here it is on my desk next to my 27 inch monitor. I'm really glad it has that classic beige plastic color.<br>
(ignore the mess of wires on my desk, I pretty much had to redo my entire space to fit this monster in!)</h5>
<br>
<br>
<br>
<br>
<br>
<br>
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<h1>END</h1>
<h3><a href="https://youtube.com/channel/UC9mP0LIjBangrnFuNJDuvAw">Watch my youtube videos here :)</a></h3>
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# Welcome to my website. I am an analog media enthusiast
and love to share in my hobbies with anyone else interested.
### I try to archive any VHS tapes that I find. I upload them to my youtube channel as long as I am
relatively confident they won't get taken down or copyrighted.
[Watch my youtube videos here!](https://youtube.com/channel/UC9mP0LIjBangrnFuNJDuvAw)
[Here is my Teespring with designs by myself and Kaz!](https://vhs-jess.creator-spring.com/)
### If you wish to contact me, you can email me at vhsjessie@gmail.com
#### Now, onto the blog!
![](https://media.discordapp.net/attachments/916115136631152790/990997441270648862/got_internet.png)
# The Wonderful World of Windows 98! (is janky)
### August 22nd, 2022
### [Forgot to take good pictures for the post but I'll update them here later]
### Last year I picked up an old Y2K era Windows 98 pc from FB marketplace. I
played around with it a bit, reading some ancient emails left on the disk,
and seeing what had been installed on it. It was a nice novelty and it came
with some cool peripherals and a neat little 800x600 monitor, but I never
really made much use of it. That was, until a few months back I decided that
I wanted to build it into a games/media creation pc. I'm not very familiar
with pc hardware from that era, but an AMD k6 seems half decent, and a M571
motherboard seemed to have a good rep online from what I could find in a few
minutes of research. So I set out to get it setup to a usable state in 2022.
![](https://media.discordapp.net/attachments/626054197325856768/1011331510529441802/IMG_20220730_163805.jpg?width=450&height=600)
### The first thing I had to do, was replace the broken CD drive. The one
in the computer would not eject, and I had no way to get any files INTO the
computer. I managed to track down an IDE dvd burner pretty easily, and got
it installed no problem. After playing around with some of the goofy programs
and clip art collection CDs I also picked up, I decided that if I was going
to be using the computer with any kind of regularity, I was going to need
a better way of transferring files than burning CDs every time.
I started watching some videos about Windows 98 and USB storage, and was
surprised that the OS could do it. (In my mind, burning CDs with win 98
seemed like an impressive thing, but then again I'm not \*that\* old.)
So I went online and found a cheap PCI card that had a number of USB ports
I could use for transferring files and got it ordered.
![](https://media.discordapp.net/attachments/626054197325856768/1011328903748526100/IMG_20220730_170035.jpg?width=600&height=500)
##### I played around with some of the art program CDs I had in the meantime
### While I was figuring out all the USB stuff and ordering the PCI card, I was
also working on upgrading the OS to 98SE. The operating system that came on
the computer was 98 First Edition. I had learned that SE is really what you
want to run, so I made the great mistake of trying to install a new OS with
no clue what I was doing. I only realized after I had gone through the install
that I had no drivers for the motherboard, and that if I wanted to use any
graphics programs, I was going to need VGA drivers, and Sound drivers if I
wanted to hear anything either. I had no idea what to do and ended up fumbling
around with drivers programs, bricking the install, and reinstalling the OS
about a dozen times until found a website hosting all the drivers I needed.
Once I had done one more install of 98SE, I installed the motherboard's drivers
and learned that when you install an operating system that many times over,
it doesn't delete everything and will leave files left over. Oh how pampered
I've been by windows 7 and onward, deleting everything when you do a fresh
install! How naieve I was filling up the Master Boot Record of the hard disk
with a bunch of trash and broken files! Now I sit with a computer that won't
function outside of safe mode because so many files are busted.
Currently I am investigating boot disks to clear the Master Boot Record and
completely wipe the drive. I am still not very knowledgeable about this stuff
but I'm going to take my time and make sure that I do it as right as possible
this time!
![](https://media.discordapp.net/attachments/626054197325856768/1011322099064913920/GOOD_TIME_MYRTLE.png)
# Dumpster Diving at a Hospital (LEGALLY, I PROMISE)
### July 25thth, 2022
![](https://media.discordapp.net/attachments/626054197325856768/1001122577646895265/unknown.png)
##### A friend of a friend found these TVs at the dumpster area of a local hospital.
### A friend of mine saw this image on their snapchat and made me aware of this lovely
little pile of TVs sitting behind a local hospital. After work that day I stopped
by the back loading bay and got to work checking these little guys over. Most of
them were in decent condition, with only a couple of them being significantly
scratched and scraped on the front tube. I haven't yet measured their screen
sizes but I'd guess they're somewhere between 12 and 14" in size. Perfect size
to load up four of them in my tiny car and bring them home with me.
![](https://cdn.discordapp.com/attachments/626054197325856768/1001119738044358666/IMG_20220722_172538.jpg)
##### The four TVs I deemed in good enough condition to bring home, with a copy of my VHS mixtape for scale.
### The TVs are a great size and just add to the already too-big collection of small
form factor CRTs I own, but they were free so who cares :). The TVs themselves are pretty
interesting and have some weird features since they were used inside a hospital.
![](https://media.discordapp.net/attachments/626054197325856768/1001127809936281700/unknown.png)
##### The 1/4 inch audio out and the toggle switch on the side of the three PDi brand TVs.
### On the side of the three smaller ones, there is a 1/4 inch jack, and a
toggle switch. After opening the TV up, the circuitboard inside has
"Pillow Speaker Board" printed on the PCB for a pillow containing
speakers so the audio from the TV doesn't disturb other people in the
hospital. The internals of this TV are also very non-standard. The board
that has that 1/4 inch jack and switch also has the TV's power cable
routed through it. I haven't seen it before in any of my other TVs.
![](https://media.discordapp.net/attachments/626054197325856768/1001129483060903956/unknown.png)
##### The Pillow Speaker Board fastened to the inside of the back shell of the TV.
### The one larger of the four TVs is a Zenith brand tv, and has an interesting
difference from the other three PDi branded models. It has a 5 pin dinn connector
on the back. It does also have a toggle switch, but no 1/4 inch audio out. I think
that the 5 pin connector may be for audio? I may be for something else as it was
the only TV of the lot that wasn't a little PDi brand one, so it may not have
been used for a patient TV.
![](https://cdn.discordapp.com/attachments/626054197325856768/1001119740426735657/IMG_20220722_170746.jpg)
##### The 5 pin dinn connector on the back of the Zenith.
### The Zenith TV has great color but will need some picture adjustment, and
without a remote to access any kind of service menu, I'll have to open it up
and use the manual adjustment pots on the mainboard. I've never done that before
and I'm very excited to try it. Hopefully I can get the picture looking good and
sized properly because its in great condition and a great size little TV.
![](https://media.discordapp.net/attachments/626054197325856768/1001131953619206215/TRUE_TRANQUILITY.png)
# Imagine a VHS mixtape in 2022
### June 13th, 2022
![](https://media.discordapp.net/attachments/626054197325856768/985967515878432848/IMG_20220610_155252.jpg)
##### My first ever VHS mixtape! I am very proud of it! :D Cover art done by my boyfriend Kaz!
###### ------------------------------------------------------------------------------------------------------
### Over the last few years I've been collecting all kinds of weird and goofy VHS tapes
from thrift stores around me. A few months ago, I decided that instead of taking a
handful of tapes to show friends whatever weird content I had discovered, that I would
instead edit a lot of similarly themed tapes together into my own tape and add a bit
of my own editing to make something special! The tape is named "Lifestyles" and has a
lot of videos on tourism, vacationing, home living, and some other little odds and ends
edited together to make a delightful little "get-away" experience.
It was extremely fun getting to create my own intro, get my friends to help me make
transition audio between tapes, and to add my own little flairs and funny edits.
I really think I made something that adds to the experience of watching the videos
and I can't wait to work on the next idea I have for a mixtape! Lifestyles should
be publicly viewable on my youtube after I'm done stroking my ego hosting watch
parties, but I'm putting the link here as a thank you for reading my website!
You can watch my VHS mixtape "Lifestyles"[HERE](https://youtu.be/n6EdRLtKIV8)
I plan on making a very small amount of physical copies to hand out to friends
and I am enjoying producing physical copies almost as much as editing the video itself!
Making something tangible that you can physically hold and point at and say "Hey,
I made this!" Is such a satisfying feeling and something I really missed.
![](https://media.discordapp.net/attachments/916115136631152790/992055738887315497/whole_new_world.png)
# A New Beast Enters The Ring!
### April 4th, 2022
![](https://media.discordapp.net/attachments/626054197325856768/960534787733454858/IMG_20220318_212541.jpg)
##### My recently picked up JVC AV-27D305. A high quality 27" Set. Very happy with it!
###### ------------------------------------------------------------------------------------------------------
### Last week I picked up this nice JVC AV-27D305. I had been looking for a nice
"Living room size" set for a while, and when I came across this for sale I jumped on it
immediately. The JVC D-series is very well known for its quality. From what I can tell,
its regarded about as highly as Sony Trinitrons, if not just behind. I can certainly
vouch for its quality after playing a few games and watching a few VHS tapes, but I have
not experienced a Sony Trinitron larger than 14" that isn't a computer monitor. I imagine
its quality wouldn't leave much to be desired though, as even watching movies over Composite
looks fantastic!
![](https://media.discordapp.net/attachments/626054197325856768/960534787116924938/IMG_20220328_081826.jpg)
##### My living room is a mess after making space for it where my old beater flat screen used to be.
###### ------------------------------------------------------------------------------------------------------
### I don't use my living room too often for watching old media, usually thats done at my desk
where I'm capturing footage for my [Youtube Channel](https://youtube.com/channel/UC9mP0LIjBangrnFuNJDuvAw). I think I will be enjoying my living
room quite a bit more now with this beautiful piece of equipment! I really love the nice
silver plastic and aesthetic of the mid 00's. I am hugely nostalgic for that time in my
life and to have something like this in my home, to be able to come home and put on
my favorite shows from that era, or play some PS2 games on my nice silver slim model,
I couldn't be happier with this pickup!
One of the biggest reasons I picked up this model was for the Component video connection.
I haven't owned a consumer CRT with component video before, and I really wanted to see
how big of a difference it makes when playing era-appropriate games. I bought a cable
and some female-female connectors so I don't have to get my hands back there every time
I want to switch consoles. I've tried a few games on it so far; God Hand(PS2), Kinetica(PS2),
FZERO GX (Wii component), LSD Dream Emulator (PS1), and they all look absolutely
fantastic! I've played all those games on a 1600x1200 Sony Trinitron PC monitor with the
consoles being fed through a video upscaler and converter (see post from March 7th), but to play
them on a TV with those connections just gives it that quality I remember from the time.
Between a matching silver PS2 for games and DVD playback, a nice Samsung VCR for tapes,
and any video game consoles I can get my hands on, my living room is looking nearly
complete as far as media consumption goes.
![](https://media.discordapp.net/attachments/916115136631152790/992055738526613504/refreshment.png)
# Fantastic Plastic, Hello Yellow!
### March 17th, 2022
![](https://media.discordapp.net/attachments/626054197325856768/954011604809293894/IMG_20220219_182439__01.jpg)
##### My daily driver, a Cherry G-80 1800 keyboard. Age has yellowed this ABS plastic to heck, but I love it.
###### ------------------------------------------------------------------------------------------------------
### Last summer I picked up four of these Cherry G-80 1800 keyboards from a dying Sears
while I was on a little road trip. Having been into custom keyboards for some time before
this trip, I was stunned when I found four of these boards sitting in a bin. If anyone else
had walked into that Sears who knew about these boards, they would have gotten snagged
immediately. I also picked up a small monochrome CRT security monitor, but that will
probably receive its own post here sometime.
All four of the boards used Cherry's "MY" switch (pronounced "M - Why") , which have zero
value in this dayand age. Fortunately for me though, two of the boards had Cherry's old ABS
plastic keycaps. These are quite high quality keycaps and I was ecstatic to find two sets
of these! The other two had Lasered PBT plastic caps which are noticably lower quality than
the doubleshot ABS plastic but still perfectly functional. All four sets are Cherry profile,
which is my favorite keycap profile to type on so I am quite happy with that.
All four boards also came with a very large amount of "Re-legendable" keycaps. These caps
have a beige plastic base, with a clear plastic top-cap that snaps on. You can create your
own legends, print them or write them onto paper, and then insert them into these caps and
create your own key legends. These caps are a very cool novelty to have, but turn into a
genuinely useful feature paired with the replacement internals I fitted these boards with.
![](https://media.discordapp.net/attachments/626054197325856768/954017390407077898/IMG_20220317_100353__01.jpg)
##### Re-legendable keycaps on a work keyboard.
###### ------------------------------------------------------------------------------------------------------
### I replaced the original PCB and switches inside the keyboard with updated and more
feature-rich internals that bring these keyboards up to 2020 spec. I used a drop-in PCB
that has VIA compatibility for full programmability, as well as modern Cherry MX switches
to keep it as "still Cherry" as possible. These keyboards can be programmed any-which-way
I could ever want, something far more useful than modern "gamer" keyboards. The switches
I used were Cherry MX Hyperglide Blacks, which are a bit stiffer-springed than the usual
keyboard switches you find nowadays. I enjoy the heavier weight, and after roughly 8-months
of regular use, they have become quite smooth as the plastics inside rub eachother smooth.
I used to be really into custom boards before I found these, but that interest has been sated.
The aesthetics of the yellowed plastic, functionality, and feel really are the best I've used.
![](https://media.discordapp.net/attachments/916115136631152790/991729004337975378/hot_and_fresh.png)
# Crouching Tiger, Hidden Gems
### March 14th, 2022
![](https://media.discordapp.net/attachments/626054197325856768/952927415477354536/IMG_20220310_192444.jpg)
##### A two-pack of 70s kung-fu movies I found at my local thrift store over the weekend.
###### ------------------------------------------------------------------------------------------------------
### Over the weekend I stopped by my usual haunt and dug through whatever new tapes I
could find. I scooped up an absolute gem of a double pack! I watched the first movie in
the pack, Shaolin Deadly Kicks, and it has got to be one of my favorite full length movies
I have on tape. Its rediculous, stupid, fast paced, goofy as all hell, and there was roughly
only about 10 minutes of slow pacing in its 1.5 hour runtime. The movie itself is a reprint,
the original having released in 1977. I had been wanting at least one movie like this for
some time, but now I have two and I couldn't be happier! I'm extremely excited to watch
the second movie in the pack and will give my impressions on it here whenever I do.
![](https://media.discordapp.net/attachments/626054197325856768/952927532892700712/Snapchat-528224235__01.jpg)
##### A DVD copy of The Texas Chainsaw Massacre 2 I also found at my local thrift purely by accident.
###### ------------------------------------------------------------------------------------------------------
### While I was thrifting, I took a quick glance at their DVD selection on the off chance
there was anything weird, and within the pile of early 2000s junk, I just happen to spy this
sitting on the back of one shelf. I genuinely couldn't believe it when I pulled it off the
shelf, but I am so glad I decided to look through the DVDs that day! The first two Texas Chainsaw
movies are some of my favorite slasher movies outside the Friday the 13th series, and finding
at least one of them physically is so cool. I don't know if the DVD actually works, as its a
used disc and I haven't checked it yet, but if its broken at least it'll look nice on a shelf.
![](https://media.discordapp.net/attachments/916115136631152790/990997441497157662/congrats_youve_won.png)
# Top of the Line Computing
### March 7th, 2022
![](https://cdn.discordapp.com/attachments/626054197325856768/950445705082863616/IMG_20220218_222256.jpg)
##### Dell E771P (left) and Sony Trinitron GDM-500PS (right). The size difference here is absolutely incredible.
The weight is also incredible (but not for my back) with the Sony monitor coming in at 79 pounds according to the service manual.
###### ------------------------------------------------------------------------------------------------------
###
I picked up a Sony Trinitron GDM-500PS computer monitor two weeks ago
and have been slowly working it into my home desk setup. It has two inputs.
One VGA port and BNC connectors for RGBHV. I didn't know anything
about RGBHV and was hoping I could just get some BNC to RCA adapters
and plug component video into it, but turns out its just a broken out form
of VGA, as far as I can tell. I have a cheap Displayport to VGA adapter that
works fine for now, but it cannot hit the monitor's maximum of 1600x1200 at 85hz.
I will have to get a different adapter for that, but I am very excited to see how that
looks in the future. The only video game console I own that will connect to the
moitor without converters is the Dreamcast, which looks absolutely stunning.
I ordered an Open Source Scan Converter to take component video and upscale
it and convert it to display on the monitor, and let me tell you, I've never seen a
crt display look this incredible. My childhood was playing ps2 games through
composite video on a mid-range consumer CRT television, and this completely
blows that into another dimension.
It was confusing trying to adjust the color settings on this unit. I bought it
from a guy who has been doing computer graphics professionally since the late 90s
and he must have had it in some kind of strange lighting environment because it
was so dim and red-biased when I got it. It took a few days of adjustments to get
it looking decent, and then another week on top of that to really figure out how
to get the color settings optimal for my environment and use-case. Now that I have
it setup how I want I am enjoying this behemoth of a monitor! I use it to play
games, watch 4:3 aspect ratio video, and use it as a recording preview when I'm
archiving VHS tapes. I'm really glad I found this thing on facebook marketplace
because these are getting pretty dang rare and this one is in excellent condition.
It should last me probably about as long as I'm interested in CRT displays, and I
am excited to have it on my desk.
![](https://cdn.discordapp.com/attachments/626054197325856768/950445704436932638/IMG_20220218_222748.jpg)
##### Here it is on my desk next to my 27 inch monitor. I'm really glad it has that classic beige plastic color.
(ignore the mess of wires on my desk, I pretty much had to redo my entire space to fit this monster in!)
# END
### [Watch my youtube videos here :)](https://youtube.com/channel/UC9mP0LIjBangrnFuNJDuvAw)
![](https://cdn.discordapp.com/attachments/626054197325856768/883719870800330772/jarvisss.jpg)
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top: 1353px; left: 71px; width: 166px; height: 216px; z-index: 12;"><div style="overflow: hidden; height: 216px; width: 166px; border: 0px solid #52A8EC; border-radius: 0px; box-shadow: none;"><img height="216" width="166" style="display: block; border-radius: 0px;" title="" alt="" src="files/nancmagweb.jpg" /></div></div><!-- </hs:element14> --><!-- <hs:element15> --><div id="element15" style="position: absolute; top: 289px; left: 236px; width: 208px; height: 83px; z-index: 13;"><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size14 TimesRoman14"><b>"Daddy, I Can't Sleep"</b><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12"><b>Life Size Wood Sculpture</b><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size10 TimesRoman10"><b>by</b><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size10 TimesRoman10"><b>Joe Bolf</b><br></font></div></div><!-- </hs:element15> --><!-- <hs:element16> --><div id="element16" style="position: absolute; top: 455px; left: 72px; width: 370px; height: 280px; z-index: 14;"><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12">This sculpture is of my daughter Gretchen at age nine.<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12">Gretchen is 49" tall. The base is an additional 12".<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12">She was featured on the cover of  the National Wood Carvers Association's magazine "Chip Chats" in the May-June 1991 issue.<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12">The doll that she is holding was Gretchen's first doll.<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12"><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12"><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12"><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12"><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12"><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12"><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12"><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="'Times New Roman', Times, serif" color="#FFFFCC" class="size12 TimesRoman12"><br></font></div></div><!-- </hs:element16> --><!-- <hs:element17> --><div id="element17" style="position: absolute; top: 704px; left: 364px; width: 358px; height: 35px; z-index: 15;"><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size14 Helvetica14">"Sea Breeze"  </font><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size10 Helvetica10">by  </font><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">Joe Bolf<br></font></div></div><!-- </hs:element17> --><!-- <hs:element18> --><div id="element18" style="position: absolute; top: 740px; left: 364px; width: 189px; height: 176px; z-index: 16;"><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12"> My former wife Cora modeled for this stunning sculpture.<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">The article on the right was<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">published in the Jan.-Feb.<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">1997 issue of "Chip Chats"<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12"><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12"><br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12"><br></font></div></div><!-- </hs:element18> --><!-- <hs:element19> --><div id="element19" style="position: absolute; top: 995px; left: 361px; width: 364px; height: 140px; z-index: 17;"><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">The experience was captured on a 30 minute video that includes wonderful scenes of moose and loons as we live on Moosehead Lake in Maine, <br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">The film climaxes with a 60 second time lapse of the entire project in which the sculpture comes to life.<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">Original music written and performed on the tenor sax by Joe Bolf creates an exciting back drop.<br></font></div></div><!-- </hs:element19> --><!-- <hs:element20> --><div id="element20" style="position: absolute; top: 1257px; left: 8px; width: 437px; height: 29px; z-index: 18;"><div style="font-size: 1px; line-height: 1px;" align="left"><font face="Helvetica, Arial, sans-serif" color="#000000" class="size10 Helvetica10"><br></font></div></div><!-- </hs:element20> --><!-- <hs:element21> --><div id="element21" style="position: absolute; top: 1258px; left: 5px; width: 439px; height: 35px; z-index: 19;"><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size14 Helvetica14">"Simple Pleasure"  </font><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size10 Helvetica10">by</font><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12"> Joe Bolf<br></font></div></div><!-- </hs:element21> --><!-- <hs:element22> --><div id="element22" style="position: absolute; top: 1337px; left: 247px; width: 196px; height: 122px; z-index: 20;"><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">This life-size sculpture was my first. Her name was Nancy and she performed with me on the piano for several years. Nancy  is 5' 9" with a 12" base.<br></font></div></div><!-- </hs:element22> --><!-- <hs:element23> --><div id="element23" style="position: absolute; top: 1579px; left: 75px; width: 369px; height: 68px; z-index: 21;"><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">The bird is guilded with 23 carat gold leaf.<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">"Chip Chats" published a full page color photo of Nancy in it's July-August, 1990 issue.<br></font></div></div><!-- </hs:element23> --><!-- <hs:element24> --><div id="element24" style="position: absolute; top: 1736px; left: 314px; width: 185px; height: 194px; z-index: 22;"><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">This is a life-size<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">clay sculpture of Cora.<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">I always begin a project <br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">with clay.<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">It saves the model a<br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">lot of time and helps <br></font></div><div style="font-size: 1px; line-height: 1px;" align="center"><font face="Helvetica, Arial, sans-serif" color="#FFFFCC" class="size12 Helvetica12">me to become familiar<br></font></div><div style="font-size: 1px; 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![](files/coraweb2.jpg)![](files/realisticpeoplezy.gif)![](files/byzy2.gif)![](files/zydivider.gif)![](files/zydivider.gif)![](files/claycora2.jpg)![](files/gretchenweb1.jpg)![](files/nancyweb4.jpg)![](files/claycora1.jpg)![](files/zyjoebolfg5.gif)![](files/gretmag1.jpg)![](files/coramag.jpg)![](files/nancmagweb.jpg)**"Daddy, I Can't Sleep"**
**Life Size Wood Sculpture**
**by**
**Joe Bolf**
This sculpture is of my daughter Gretchen at age nine.
Gretchen is 49" tall. The base is an additional 12".
She was featured on the cover of  the National Wood Carvers Association's magazine "Chip Chats" in the May-June 1991 issue.
The doll that she is holding was Gretchen's first doll.
"Sea Breeze"  by  Joe Bolf
 My former wife Cora modeled for this stunning sculpture.
The article on the right was
published in the Jan.-Feb.
1997 issue of "Chip Chats"
The experience was captured on a 30 minute video that includes wonderful scenes of moose and loons as we live on Moosehead Lake in Maine,Â
The film climaxes with a 60 second time lapse of the entire project in which the sculpture comes to life.
Original music written and performed on the tenor sax by Joe Bolf creates an exciting back drop.
"Simple Pleasure"  by Joe Bolf
This life-size sculpture was my first. Her name was Nancy and she performed with me on the piano for several years. Nancy  is 5' 9" with a 12" base.
The bird is guilded with 23 carat gold leaf.
"Chip Chats" published a full page color photo of Nancy in it's July-August, 1990 issue.
This is a life-size
clay sculpture of Cora.
I always begin a projectÂ
with clay.
It saves the model a
lot of time and helpsÂ
me to become familiar
with her features.
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<td background="images/marb093.jpg" width="42%">
<div align="center">
<p><font color="#CCCCCC" size="5">CLIFFORD K WELDING</font></p>
<p><font color="#CCCCCC" size="4">LT NOVEMBER 21 1968</font></p>
</div>
</td>
<td background="images/k132.jpg" width="14%">
<div align="center"><img src="images/usaflag.gif" height="53" width="88"></div>
</td>
<td background="images/marb093.jpg" width="44%">
<div align="center">
<p><font color="#CCCCCC" size="5">STANLEY NORRIS GREEN</font></p>
<p><font color="#CCCCCC" size="4">SGT November 21 1968</font></p>
</div>
</td>
</tr>
</tbody></table>
<p><font color="#FFFFFF" face="Georgia, Times New Roman, Times, serif" size="6"><i><b><a href="http://b717.homestead.com/index.html"><img src="http://www.cavpilot.com/images/KIA.GIF" height="159" border="0" width="672"></a>
</b></i></font></p>
<h3> </h3>
</div>
</td>
</tr>
</tbody></table>
<p> </p>
<p> </p>
<p> </p>
</center>
</div>
<div align="center">
<center>
<table cols="3" height="327" align="center" border="0" cellpadding="0" cellspacing="0" width="96%">
<tbody><tr>
<td bordercolor="#000000" height="390" align="center" valign="middle" width="42%">
<p align="center"><font color="#D8A888" size="4"> <font size="5"> </font></font></p>
<p align="left">
<font face="Georgia, Times New Roman, Times, serif" size="4" color="#FF3333">
<font color="#D8A888" face="Georgia, Times New Roman, Times, serif" size="3">Fortunate Son - Creedence Clearwater
</font></font><br/><br/><audio src="music/fortune_son.mp3" preload="auto" /></p>
<p align="left">
<font color="#D8A888" face="Georgia, Times New Roman, Times, serif" size="3">Run Through The Jungle-Creedence Clearwater
</font><br/><br/><audio src="music/run_through.mp3" preload="auto" /></p>
</td>
</tr>
</tbody></table>
<p> </p>
</center>
</div>
<p> </p>
<table height="410" width="99%">
<tbody><tr>
<td height="309">
<p align="center"> </p>
<p align="center"><b><font color="#FF3333" face="BakerSignet" size="4">"Our
Marine Brothers"</font></b></p>
<div align="center">
<p><img src="images/namm40.jpg" height="204" border="0" width="433"></p>
<p><b><font color="#FFFF00" face="BakerSignet" size="4"><a href="http://www.marines.com/being-a-marine/roles-in-the-corps/ground-combat-element/scout-sniper">Marine
Scout Snipers</a></font></b></p>
<p><b><font color="#FF3333" face="BakerSignet" size="4">"Check this
site out, recently updated with pictures from Iraq "</font></b></p>
<p><img src="images/bobfire.gif" height="50" width="514"></p>
<p>
</p></div>
</td>
</tr>
</tbody></table>
<p> </p>
<p> </p>
<p> </p>
<hr>
<p> </p>
<div align="center">
<center>
<table cols="2" bordercolordark="#999999" height="548" align="center" border="0" bordercolor="#999999" width="97%">
<tbody><tr>
<td bordercolor="#999999" height="561" align="center">
<p><font color="#C0C0C0"><img src="images/forever_heroes.jpg" height="435" border="0" width="311"></font></p>
</td>
<td height="561" align="center">
<p align="center"><font color="#C8B080" face="BakerSignet" size="4"><b>THE
VIET NAM VET</b></font> </p>
<p align="center"><font color="#C8B080"><b><font face="BakerSignet" size="3">It's
a very unique club -</font> <font face="BakerSignet" size="3"><br>
I see it everywhere -</font> <font face="BakerSignet" size="3"><br>
I see man embracing man -</font> <font face="BakerSignet" size="3"><br>
A tear that says, "I care!".</font> <font face="BakerSignet" size="3"><br>
There's a special look in eyes</font> <font face="BakerSignet" size="3"><br>
That words cannot explain -</font> <font face="BakerSignet" size="3"><br>
I see joy for this life -</font> <font face="BakerSignet" size="3"><br>
Sometimes the living pain.</font> <font face="BakerSignet" size="3"><br>
There's a camaraderie</font> <font face="BakerSignet" size="3"><br>
That's very rare these days -</font> <font face="BakerSignet" size="3"><br>
They let it show without shame</font> <font face="BakerSignet" size="3"><br>
In so many different ways.</font> <font face="BakerSignet" size="3"><br>
I wasn't there, (thank the Lord.)</font> <font face="BakerSignet" size="3"><br>
So I can't really know -</font> <font face="BakerSignet" size="3"><br>
I can only sense and feel</font> <font face="BakerSignet" size="3"><br>
Those things which I see show.</font> <font face="BakerSignet" size="3"><br>
The patience, understanding -</font> <font face="BakerSignet" size="3"><br>
Which only they can feel -</font> <font face="BakerSignet" size="3"><br>
There is something very special</font> <font face="BakerSignet" size="3"><br>
And something very real.</font> <font face="BakerSignet" size="3"><br>
Del Jones</font> </b></font></p>
</td>
</tr>
</tbody></table>
</center></div>
<p> </p>
<hr>
<p align="center"> </p>
<div align="center">
<center>
<table height="503" align="center" border="0" width="96%">
<tbody><tr>
<td align="center" width="31%"> <img src="http://www.cavpilot.com/images/2EAGLE.JPG" height="147" width="129"></td>
<td align="center" width="39%"><img src="images/goldwall.jpg" height="370" align="middle" width="246"> </td>
<td align="center" width="30%">
<p><img src="images/flag2.gif" height="77" align="middle" border="0" width="130"></p>
<p> <font color="#FFFF33" face="Verdana, Arial, Helvetica, sans-serif" size="2"><b><i>"That
Ragged Old Flag"</i></b></font></p>
<p><audio src="music/johny.mp3" preload="auto" /></p>
</td>
</tr>
</tbody></table>
<p> </p></center></div>
<hr>
<p> </p>
<table bordercolordark="#987C60" height="550" align="center" background="images/k132.jpg" border="4" width="40%">
<tbody><tr>
<td height="329" width="31%">
<div align="center">
<p> </p>
<p><font color="#C89440" face="BakerSignet" size="4"><b>CW2 Mike Piccone</b></font>
<font color="#C89440" face="BakerSignet" size="4"><b><br>
2/17 Cavalry 101 Airborne RVN 67-68 <br>
7/17 Cavalry 1st AVN BDE RVN 68-69 <br>
57th Assault Helicopter Company RVN 69</b></font></p>
<p><img src="images/mstavn.gif" height="80" align="middle" width="200"> <img src="images/eaglbrn.gif" height="78" align="middle" width="114"></p>
<p><img src="images/vnribbons1.gif" height="40" align="middle" width="270"></p>
<p><img src="http://www.cavpilot.com/images/valorousunit.GIF" height="40" width="110"><img src="http://www.cavpilot.com/images/us-pres-unit-citation.GIF" height="40" width="110"></p>
<p><img src="http://www.cavpilot.com/images/vietnamcrossofgallantry.JPG" height="40" width="110"></p>
<p><img src="http://www.cavpilot.com/images/17crestt.GIF" height="117" width="91"></p>
</div>
</td>
</tr>
</tbody></table>
<p align="center"> </p>
<p align="center"> </p>
<p align="center"><a href="https://www.flickr.com/photos/130067715@N08/"><img src="images/myphotos.gif" height="41" border="0" width="317"></a></p>
<p align="center"><a href="https://www.flickr.com/photos/130067715@N08/"><img src="http://www.cavpilot.com/images/ME.JPG" height="173" border="0" width="247"></a></p>
<p align="center"><font color="#FF3333" face="Times New Roman, Times, serif" size="5"><img src="images/Newyllo.gif" height="25" width="32">"Four
pages including our troops in Iraq"</font></p>
<hr>
<p align="center"> </p>
<p align="center"> </p>
<table height="451" align="center" border="0" width="95%">
<tbody><tr>
<td height="489" width="21%">
<div align="center">
<p> </p>
<p><a href="http://www.vhfcn.org/"> <img src="images/cougar11.gif" height="121" border="0" width="104"></a></p>
<p><font color="#FF0000" face="BakerSignet" size="3"><a href="http://www.vhfcn.org/">Visit
VHFCN</a></font></p>
</div>
</td>
<td bordercolor="#987C60" height="489" width="57%">
<div align="center">
<p>
</p><p><img src="images/huey.jpg" height="354" width="432"></p>
<p><font color="#FF3333" size="3"><b>"Inserting Blues"</b></font></p>
</div>
</td>
<td height="489" width="22%">
<div align="center">
<p> </p>
<p> </p>
<p><a href="http://www.57thahc.com/"><img src="images/1avn.gif" height="135" border="0" width="93"></a></p>
<p><a href="http://www.57thahc.com/"><font color="#FF0000" face="BakerSignet" size="3">57thAHC Gladiators </font></a></p>
<p> </p>
</div>
</td>
</tr>
</tbody></table>
<p> </p><hr>
<p> </p>
<p align="center"> </p>
<p align="center"> </p>
<div align="center"> </div>
<p align="center"><br>
</p>
<div align="center">
<center>
<table height="224" align="center" border="0" width="79%">
<tbody><tr>
<td width="76%">
<div align="center">
<p><a href="http://thewall-usa.com//"><img src="images/wall.gif" height="30" border="0" width="610"></a></p>
<p><a href="http://thewall-usa.com//"><img src="images/patrol.jpg" height="317" border="0" width="485"></a></p>
<p><font color="#FF3333" face="Times New Roman, Times, serif" size="4">Visit
this incredible link</font></p>
</div>
</td>
</tr>
</tbody></table>
<p> </p>
<p> </p>
<hr>
<p> </p>
<p> </p>
<p> </p>
<p> </p>
<table cols="2" height="29%" align="center" width="78%">
<tbody><tr>
<th bordercolor="#383C38" height="50%" width="63%"> <img src="images/remember.jpg" height="128" align="right" width="294"></th>
<td bordercolor="#999999" align="left" width="37%"><img src="http://www.cavpilot.com/images/vvm07.JPG" height="305" width="171">
</td>
</tr>
</tbody></table>
<p> </p>
<p><font color="#FF3333" face="Times New Roman, Times, serif" size="4">Please
click on any picture to visit "From The Other Side"</font></p>
<table cols="2" bordercolordark="#987C60" height="25%" border="4" width="96%">
<tbody><tr>
<td align="center" width="48%"><a href="http://www.war-stories.com/from-the-other-side-camunes-1967.htm"><img src="images/larry6m.jpg" height="273" border="0" width="372"></a></td>
<td align="center" width="52%"><a href="http://www.war-stories.com/from-the-other-side-camunes-1967.htm"><img src="images/wallbike.jpg" height="263" border="0" width="381"></a></td>
</tr>
</tbody></table>
</center></div><div align="center"><center>
<table cols="2" bordercolordark="#987C60" height="22%" border="4" width="96%">
<tbody><tr>
<td align="center" width="48%"><a href="http://www.war-stories.com/from-the-other-side-camunes-1967.htm"><img src="images/wall01.jpg" height="234" border="0" width="324"></a></td>
<td align="center" width="52%"><a href="http://www.war-stories.com/from-the-other-side-camunes-1967.htm"><img src="images/reflect.jpg" height="262" border="0" width="404"></a></td>
</tr>
</tbody></table>
</center></div><div align="center"><center>
<table cols="2" bordercolordark="#987C60" height="8%" border="4" width="96%">
<tbody><tr>
<td height="267" align="center" width="48%">
<p><a href="http://www.war-stories.com/from-the-other-side-camunes-1967.htm"><img src="images/larry5m.jpg" height="219" border="0" width="457"></a> </p>
</td>
<td height="267" align="center" width="52%">
<p align="center"><a href="http://www.war-stories.com/from-the-other-side-camunes-1967.htm"><img src="images/larry10.jpg" height="264" border="0" width="375"></a></p>
</td>
</tr>
</tbody></table>
<p> </p>
</center>
</div>
<table height="322" align="center" border="0" width="96%">
<tbody><tr>
<td height="298" width="13%">
<div align="center"><img src="images/flag2.gif" height="50" align="middle" width="91"></div>
</td>
<td height="298" width="74%">
<div align="center">
<p align="left"><font color="#FFCC99" face="Georgia, Times New Roman, Times, serif" size="3"><b>I
read the eulogy "From the Other Side" tonight.. I was moved to tears,
I must admit it. My father served in Vietnam, for three years, 1965-68.
He came home to me and momma, and after reading the story, I am truly
thankful. I cannot claim to know what you went through during that terrible
time in our country's past, and I hope that I and my comrades won't
ever have to know. But, after visiting your homepage and looking at
the remembrances of a time I only know from television, I am truly proud
to say that I can count you as a friend. I hope that my leaders have
the foresight to learn from this country's past, and that they all visit
a place like this. Maybe then we won't be putting up any more memorials
to this country's dead heroes. Your friend and comrade-in-arms,</b></font></p>
<p><font color="#FFCC99" face="Georgia, Times New Roman, Times, serif" size="3"><b>
SGT James McEdwards, 110th MI BN, 10th Mountain Division. </b></font></p>
</div>
</td>
<td height="298" width="13%">
<div align="center"><img src="images/flag2.gif" height="50" width="91"></div>
</td>
</tr>
</tbody></table>
<hr>
<div align="center">
<table height="894" align="center" width="96%">
<tbody><tr>
<td height="665" width="76%">
<div align="center">
<!--------------- END Vietnam Veteran Proud SITERING CODE ------------->
<p></p>
<center>
<a href="mailto:cavpilot@bellsouth.net">17th Cavalry Memorial Site</a>
is a member of the
</center>
<center>
<img src="images/banbud.jpg" height="56" width="411">
</center>
<center>
Want to join the ring? Get <a href="http://dir.webring.org/rw?d=Government___Politics/Military/Veterans/Vietnam_Veterans" target="_top">info</a>
<b>Visit other sites in the ring now!</b>
</center>
<!--END Copy Here -->
<p> </p>
<p><a href="http://www.vietnamexp.com/Awards/top_100.htm"><img src="images/TopSites.jpg" height="225" border="0" width="164"></a>
</p>
<center>
<b><font color="#FF3333">Click on this link to vote for this site</font></b>
<br>
<font face="arial,verdana" size="1"></font>
</center>
</div>
</td>
</tr>
<tr>
<td height="129" width="76%">
<div align="center">
<center>
<p> </p>
<p><a href="http://www.ojc.org/images/docsgraphics.htm"><img src="images/graphban3.jpg" height="44" border="0" width="343"></a>
</p>
</center>
<p> </p>
</div>
</td>
</tr>
</tbody></table>
<p> </p>
<hr>
<p> </p>
</div>
<table height="341" align="center" bordercolor="#000000" width="95%">
<tbody><tr>
<td width="41%"><font color="#FFFFFF" face="BakerSignet" size="4"><b>LINKS
:</b></font></td>
<td width="59%"> </td>
</tr>
<tr>
<td width="41%"><b><font face="BakerSignet"><a href="http://lcweb2.loc.gov/pow/powhome.html">POW
Home Page and Official Information</a></font></b></td>
<td width="59%"><b><font color="#FF3300" face="BakerSignet"><a href="http://marinescoutsniper.com/">
Marine Scout Snipers</a></font> </b></td>
</tr>
<tr>
<td width="41%"><b><font color="#FF3300" face="BakerSignet"><a href="http://www.arlingtoncemetery.com/">Arlington
National Cemetery</a></font></b></td>
<td width="59%"><b><font color="#FF3300" face="BakerSignet"><a href="http://www.usmc.mil/">Marine
Home Page</a></font></b></td>
</tr>
<tr>
<td width="41%">
<p><b><font face="BakerSignet"><a href="http://www.vhfcn.org/">Viet Nam
Helicopter Flight Crew Association</a></font></b></p>
</td>
<td width="59%"><b><font color="#FF3300" face="BakerSignet"><a href="http://www.specialoperations.com/">Special
Operations</a></font></b></td>
</tr>
<tr>
<td width="41%"><b><font face="BakerSignet"><a href="http://www.vhpa.org/">Viet
Nam Helicopter Pilots Association</a></font></b></td>
<td width="59%"><b><font color="#FF3300" face="BakerSignet"><a href="http://www.vetfriends.com/">Vet
Freinds </a></font></b></td>
</tr>
<tr>
<td width="41%"><b><font color="#FF0000" face="BakerSignet"><a href="http://www.sfahq.org/">Special
Forces Association</a> </font></b></td>
<td width="59%"><font color="#FF0000" face="BakerSignet"><b> <a href="http://www.ranger.org/">US
Army Ranger Association</a></b></font></td>
</tr>
</tbody></table>
<p> </p><table height="92" align="center" border="0" width="82%">
<tbody><tr>
<td height="103" width="61%">
<div align="center">
<p> </p>
<p> </p>
<p><a href="sign_guestbook.html">Sign My Guestbook</a>
<a href="view_guestbook.html">View My Guestbook</a><br>
</p>
<p> </p>
<p><a href="mailto:cavpilot@bellsouth.net"><img src="http://www.cavpilot.com/images/CAVNET.GIF" height="40" border="0" width="329"></a>
</p>
</div>
</td>
</tr>
</tbody></table>
<center>
<p> </p>
</center>
<p align="center"> </p>
<p align="center"> </p>
<p align="center"> </p>
<p align="center"> </p>
<p> </p>
<p><a href="http://www.webmasters.com.pk" title="Website Developed by Webmasters" id="link">Website Developed By Webmasters</a></p>
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|
17th Cavalry Memorial Page
```
```
| | | | |
| --- | --- | --- | --- |
|
| | | |
| --- | --- | --- |
|
CLIFFORD K WELDING
LT NOVEMBER 21 1968
| |
STANLEY NORRIS GREEN
SGT November 21 1968
|
|
| |
| --- |
|
Fortunate Son - Creedence Clearwater
Run Through The Jungle-Creedence Clearwater
|
| |
| --- |
|
**"Our
Marine Brothers"**
**[Marine
Scout Snipers](http://www.marines.com/being-a-marine/roles-in-the-corps/ground-combat-element/scout-sniper)**
**"Check this
site out, recently updated with pictures from Iraq "**
|
---
| | |
| --- | --- |
| | **THE
VIET NAM VET**
**It's
a very unique club -
I see it everywhere -
I see man embracing man -
A tear that says, "I care!".
There's a special look in eyes
That words cannot explain -
I see joy for this life -
Sometimes the living pain.
There's a camaraderie
That's very rare these days -
They let it show without shame
In so many different ways.
I wasn't there, (thank the Lord.)
So I can't really know -
I can only sense and feel
Those things which I see show.
The patience, understanding -
Which only they can feel -
There is something very special
And something very real.
Del Jones** |
---
| | | |
| --- | --- | --- |
| | |
***"That
Ragged Old Flag"***
|
---
| |
| --- |
|
**CW2 Mike Piccone**
**2/17 Cavalry 101 Airborne RVN 67-68
7/17 Cavalry 1st AVN BDE RVN 68-69
57th Assault Helicopter Company RVN 69**
|
[![](images/myphotos.gif)](https://www.flickr.com/photos/130067715@N08/)
[![](http://www.cavpilot.com/images/ME.JPG)](https://www.flickr.com/photos/130067715@N08/)
![](images/Newyllo.gif)"Four
pages including our troops in Iraq"
---
| | | |
| --- | --- | --- |
|
[Visit
VHFCN](http://www.vhfcn.org/)
|
**"Inserting Blues"**
|
[57thAHC Gladiators](http://www.57thahc.com/)
|
---
| |
| --- |
|
Visit
this incredible link
|
---
| | |
| --- | --- |
| | |
Please
click on any picture to visit "From The Other Side"
| | |
| --- | --- |
| | |
| | |
| --- | --- |
| | |
| | |
| --- | --- |
| | |
| | | |
| --- | --- | --- |
| |
**I
read the eulogy "From the Other Side" tonight.. I was moved to tears,
I must admit it. My father served in Vietnam, for three years, 1965-68.
He came home to me and momma, and after reading the story, I am truly
thankful. I cannot claim to know what you went through during that terrible
time in our country's past, and I hope that I and my comrades won't
ever have to know. But, after visiting your homepage and looking at
the remembrances of a time I only know from television, I am truly proud
to say that I can count you as a friend. I hope that my leaders have
the foresight to learn from this country's past, and that they all visit
a place like this. Maybe then we won't be putting up any more memorials
to this country's dead heroes. Your friend and comrade-in-arms,**
**SGT James McEdwards, 110th MI BN, 10th Mountain Division.**
| |
---
| |
| --- |
|
[17th Cavalry Memorial Site](mailto:cavpilot@bellsouth.net)
is a member of the
Want to join the ring? Get [info](http://dir.webring.org/rw?d=Government___Politics/Military/Veterans/Vietnam_Veterans)
**Visit other sites in the ring now!**
**Click on this link to vote for this site**
|
|
|
---
| | |
| --- | --- |
| **LINKS
:** | |
| **[POW
Home Page and Official Information](http://lcweb2.loc.gov/pow/powhome.html)** | **[Marine Scout Snipers](http://marinescoutsniper.com/)** |
| **[Arlington
National Cemetery](http://www.arlingtoncemetery.com/)** | **[Marine
Home Page](http://www.usmc.mil/)** |
| **[Viet Nam
Helicopter Flight Crew Association](http://www.vhfcn.org/)** | **[Special
Operations](http://www.specialoperations.com/)** |
| **[Viet
Nam Helicopter Pilots Association](http://www.vhpa.org/)** | **[Vet
Freinds](http://www.vetfriends.com/)** |
| **[Special
Forces Association](http://www.sfahq.org/)** | **[US
Army Ranger Association](http://www.ranger.org/)** |
| |
| --- |
|
[Sign My Guestbook](sign_guestbook.html)
[View My Guestbook](view_guestbook.html)
|
[Website Developed By Webmasters](http://www.webmasters.com.pk "Website Developed by Webmasters")
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| https://marathon.bungie.org/story/ |
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<font size="1"><b><img alt="Celestial Exploring" height="158" width="500" src="../../celes/celes_images/celes_logo_w.gif"></b></font><br>
<p></p>
<p><font size="3">In the Far future<br>
People will go to stars in the universe,<br>
getting their dream --- living in the New World, come true.</font></p>
<p><font size="3">But, they will never forget their Home Planet --- the earth.<br>
This is the story of travels in the celestial world<br>From far stars to the Ultimate Heaven --- the earth in the farther future.</font></p>
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<a href="ambiente_e.html"><b><font size="3">Ambiente</font></b></a></center>
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<a href="tranq_e.html"><b><font size="3">Tranquillity</font></b></a></div>
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<a href="reflection_e.html"><b><font size="3">Reflection</font></b></a></div>
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<a href="prism_e.html"><b><font size="3">Prism Island</font></b></a></div>
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<td width="120">
<center>
<a href="crystal_e.html"><b><font size="3">Crystal Evening</font></b></a></center>
</td>
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<center>
<a href="palace_e.html"><font size="3"><b>Back into<br>
the Palace</b></font></a></center>
</td>
<td width="120">
<center>
<a href="eternal_e.html"><b><font size="3">Eternal Dance</font></b></a></center>
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<center>
<a href="synchro_e.html"><b><font size="3">¿<br>
Synchronicity</font></b></a></center>
</td>
</tr>
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<td width="120" height="30"></td>
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<div align="center">
<a href="Infinity_e.html"><b><font size="3">Infinity</font></b></a></div>
</td>
<td width="110">
<div align="center">
<a href="inspiration_e.html"><b><font size="3">Inspiration</font></b></a></div>
</td>
<td width="110">
<div align="center">
<a href="everlasting_e.html"><b><font size="3">Everlasting<br>
Song</font></b></a></div>
</td>
<td width="110">
<div align="center">
<a href="white_p_e.html"><font size="3"><b>Hearty<br>
Welcome<br>
(white palace)</b> </font></a></div>
</td>
<td width="110">
<div align="center">
<a href="opal_e.html"><font size="3"><b>Hearty<br>
Welcome<br>
(opal gate)</b></font></a></div>
</td>
<td width="110">
<div align="center">
<a href="pacific_e.html"><font size="3"><b>Hearty<br>
Welcome<br>
(pacific)</b></font></a></div>
</td>
<td width="110">
<div align="center">
<a href="bless_e.html"><b><font size="3">Blessing</font></b></a></div>
</td>
</tr>
</table>
<p></p>
<hr>
<a href="../index.html" target="_self"><font size="2"><img src="../../image/johlogol.gif" alt="HOME" width="88" height="32" x-sas-useimagewidth x-sas-useimageheight border="0" align="middle"></font></a></center>
</body>
</html> |
KAGAYA Celestial Exploring
**![Celestial Exploring](../../celes/celes_images/celes_logo_w.gif)**
In the Far future
People will go to stars in the universe,
getting their dream --- living in the New World, come true.
But, they will never forget their Home Planet --- the earth.
This is the story of travels in the celestial world
From far stars to the Ultimate Heaven --- the earth in the farther future.
---
[**Celestial Exploring Story**](celes_story_e.html)*---*
| |
| --- |
| |
|
|
|
[**Earthlight**](earthlight_e.html) |
| | | | | | | |
| --- | --- | --- | --- | --- | --- | --- |
| | | | | | | |
|
[Ambiente](ambiente_e.html) |
[Tranquillity](tranq_e.html) |
[Passage](splendor_e.html) |
[Reflection](reflection_e.html) |
[Serenity](serenity_e.html) |
[Passage](passage_e.html) |
[Prism Island](prism_e.html) |
|
[**Ambiente**](ambiente_e.html) |
[**Tranquillity**](tranq_e.html) |
**[Splendor](splendor_e.html)** |
[**Reflection**](reflection_e.html) |
[**Serenity**](serenity_e.html) |
[**Passage**](passage_e.html) |
[**Prism Island**](prism_e.html) |
| | | | |
| --- | --- | --- | --- |
| | | | |
|
[Crystal Evening](crystal_e.html) |
[Back into the Palace](palace_e.html) |
[Eternal Dance](eternal_e.html) |
[Synchronicity](synchro_e.html) |
|
[**Crystal Evening**](crystal_e.html) |
[**Back into
the Palace**](palace_e.html) |
[**Eternal Dance**](eternal_e.html) |
[**¿
Synchronicity**](synchro_e.html) |
| | | | |
| | | | | | | |
| --- | --- | --- | --- | --- | --- | --- |
|
[Infinity](Infinity_e.html) |
[Inspiration](inspiration_e.html) |
[Everlasting Song](everlasting_e.html) |
[white palace](white_p_e.html) |
[opal gate](opal_e.html) |
[Pacific](pacific_e.html) |
[Blessing](bless_e.html) |
|
[**Infinity**](Infinity_e.html) |
[**Inspiration**](inspiration_e.html) |
[**Everlasting
Song**](everlasting_e.html) |
[**Hearty
Welcome
(white palace)**](white_p_e.html) |
[**Hearty
Welcome
(opal gate)**](opal_e.html) |
[**Hearty
Welcome
(pacific)**](pacific_e.html) |
[**Blessing**](bless_e.html) |
---
[![HOME](../../image/johlogol.gif)](../index.html)
| http://www.kagayastudio.com/english/celes_e/ |
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An appropriate representation of the requested resource could not be found on this server. This error was generated by Mod\_Security.
| https://www.anatomyatlases.org/ |
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<option value="https://www.drudgereport.com">Drudge Report</option>
<option value="/first.html">First Things</option>
<option value="https://gasprices.aaa.com/">Gas Prices</option>
<option value="https://news.google.com/">GoogleNews</option>
<option value="tophomework.html">HomeworkHelp</option>
<option value="#fun">Just For Fun</option>
<option value="https://www.lotteryusa.com/">Lottery Results</option>
<option value="https://www.marketwatch.com/">MarketWatch</option>
<option value="https://www.yahoo.com/entertainment/movies/">Movies</option>
<option value="/paper.html">Newspapers</option>
<option value="https://www.reuters.com/">Reuters</option>
<option value="/newsrch.html">SearchEngines</option>
<option value="toc.html">SiteMap</option>
<option value="httpsa://www.espn.com/">Sports</option>
<option value="https://www.irs.gov/newsroom/resources-to-help-you-prepare-your-tax-return-and-resolve-tax-disputes">Tax Resources</option>
<option value="https://www.tvguide.com/Listings/">TV</option>
<option value="https://upi.com/">UPI</option>
<option value="https://www.weather.com/">Weather</option>
<option>=====</option>
<option> NET TOOLS:</option>
<option value="anti.html">Ad Blockers</option>
<option value="https://apwg.org/">Antiphishing</option>
<option value="https://www.december.com/net/tools/">Net Tools</option>
<option value="https://www.speedtest.net/">Speed Test</option>
<option value="compsoft.html">Software</option>
<option value="https://lookup.icann.org/">WhoIs</option>
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<span class="rd_heading_small">REFERENCE DESK:</span>
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<option value="/topalman.html">Almanacs</option>
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<option value="/topbiog.html">Biographies</option>
<option value="/topcalc.html">Calculators</option>
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<option value="/topcount.html">Countries</option>
<option value="/topdict.html">Dictionaries</option>
<option value="https://maps.randmcnally.com">DriveDirections</option>
<option value="/doitself.html">Do-it-yourself</option>
<option value="/topdocs.html">Documents</option>
<option value="/topency.html">Encyclopedias</option>
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<option value="https://www.50states.com/">States</option>
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<span class="rd_heading">HEADLINE NEWS:</span><br>
<a href="https://www.bing.com/news">Bing News </a> |
<a href="https://news.google.com/">Google News </a> |
<a href="https://news.yahoo.com/">Yahoo News </a>
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<span class="rd_heading">MONEY STATS:</span><br>
<a href="https://www.usdebtclock.org/">Debt Clock</a> |
<a href="https://www.fdic.gov/bank/individual/failed/banklist.html">Failed Banks</a> <br>
<a href="https://www.cnbc.com/quotes/.DJI">DOW</a> |
<a href="https://www.cnbc.com/quotes/.IXIC">NASDAQ</a> |
<a href="https://www.bloomberg.com/energy">Oil</a> |
<a href="https://www.gasbuddy.com/gaspricemap">Gas</a> |
<a href="https://finance.yahoo.com/currencies">Dollar</a> |
<a href="https://goldprice.org/">Gold</a>
<span id="news_photos" class="no_mobile">
<hr>
<span class="rd_heading">NEWS PHOTOS:</span><br>
<a href="https://www.apimages.com/">AP News Images</a> |
<a href="https://www.bbc.co.uk/news/in_pictures">BBC</a> |
<a href="https://www.nytimes.com/section/multimedia">NYT</a> |
<a href="https://www.reuters.com/news/pictures">Reuters</a> |
<a href="https://www.upi.com/News_Photos/">UPI</a> |
<a href="https://www.washingtonpost.com/photography/">Wash. Post</a>
</span>
<span id="news_photos" class="no_mobile">
<hr>
<span class="rd_heading">NEWS VIDEOS:</span><br>
<a href="https://abcnews.go.com/Video">ABC</a> |
<a href="https://apnews.com/hub/videos">AP</a> |
<a href="https://www.cbsnews.com/video/">CBS</a> |
<a href="http://www.cnn.com/video/">CNN</a> |
<a href="https://video.foxnews.com/">FOX</a> |
<a href="https://www.nbcnews.com/video">NBC</a> |
<a href="http://www.nytimes.com/video/">NYT</a> |
<a href="https://www.reuters.com/video/">Reuters</a> |
<a href="https://www.upi.com/Video/">UPI</a> |
<a href="https://www.usatoday.com/media/latest/videos/news/">USA Today</a>
</span>
<hr>
<span class="rd_heading">MORE HEADLINES:</span><br>
<a href="https://abcnews.go.com/">ABC</a> |
<a href="https://apnews.com/hub/ap-top-news">AP Wire</a> |
<a href="https://www.cbsnews.com/">CBS</a> |
<a href="https://www.cnn.com/">CNN</a> |
<a href="https://www.foxnews.com/">FOX</a> |
<a href="https://www.msnbc.com/">MSNBC</a> |
<a href="https://www.nbcnews.com/">NBC</a> |
<a href="https://www.npr.org/">NPR</a> |
<a href="https://www.nytimes.com/">NYT</a> |
<a href="https://www.reuters.com/">Reuters</a> |
<a href="https://www.upi.com/">UPI</a> |
<a href="https://www.usatoday.com/">USA Today</a> |
<a href="https://www.wsj.com/">WSJ</a>
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<span class="rd_heading">WEATHER RESOURCES:</span><br>
Current Weather:<br>
<span class="small_text">(Enter City, ST or Zip Code, or ST)</span><br>
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<ul>
<li><a href="https://www.extremeweatherwatch.com/">Extreme Weather Watch</a></li>
<li><a href="http://www.lightningmaps.org/realtime?lang=en">Real Time Lightning Map</a></li>
<li><a href="http://www.intellicast.com/National/Radar/Current.aspx?animate=true">U.S. Radar Loop</a></li>
<li><a href="https://www.weather.gov/">National Weather Service</a></li>
<li><a href="https://www.nhc.noaa.gov">National Hurricane Center</a></li>
<li><a href="https://www.weather.gov/safety/">National Weather Service - Weather Hazards</a></li>
<li><a href="https://www.wunderground.com/wundermap?zoom=5&lat=37.80307138624724&lon=-90.50826873347978&wxstn=0&radar=0&severe=1">Severe Weather Map</a></li>
<li><a href="https://vortex.plymouth.edu/mapwall/sfc/global/loop.html?region_name=us&prod_name=temps">US Surface Temps</a>
<li><a href="https://climate.nasa.gov/vital-signs/global-temperature/">Global Land & Sea Temps </a></li>
<li><a href="http://www.stormsurfing.com/cgi/display_alt.cgi?a=glob_250">Global Jet Stream Wind Map</a></li>
<li><a href="https://earth.nullschool.net/">Earth Wind Map</a></li>
<li><a href="http://hint.fm/wind/">US Wind Map</a></li>
<li><a href="https://www.weather.gov/safety/cold-wind-chill-chart">US Wind Chill Temps</a></li>
<li><a href="https://www.wunderground.com">Weather Underground: Forecasts</a></li>
<li><a href="weath1.html">More >></a></li>
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</div>
<div id="news_features">
<span class="rd_heading">NEWS FEATURES:</span><br>
<a href="https://news.yahoo.com/">Most Popular</a> |
<a href="https://news.yahoo.com/world/">World</a> |
<a href="https://news.yahoo.com/us/">USA</a> |
<a href="https://www.yahoo.com/news/weather/">Weather</a> |
<a href="https://finance.yahoo.com/">Business</a> |
<a href="https://www.yahoo.com/news/politics">Politics</a> |
<a href="https://www.washingtonpost.com/opinions/">Opinion</a> |
<a href="https://sports.yahoo.com/">Sports</a> |
<a href="https://ew.com/">Entertainment</a> |
<a href="https://news.yahoo.com/health/">Health</a> |
<a href="https://news.yahoo.com/science/">Science</a> |
<a href="https://news.google.com/topics/CAAqJggKIiBDQkFTRWdvSUwyMHZNRGRqTVhZU0FtVnVHZ0pWVXlnQVAB?oc=3&ceid=US:en">Tech</a> |
<a href="https://www.editorialcartoonists.com/">Political Cartoons</a> |
<a href="https://www.yahoo.com/news/odd/">Odd</a>
</div>
<div id="positive_good_news">
<span class="rd_heading">POSITIVE, GOOD NEWS:</span><br>
<ul>
<li><a href="https://news.gallup.com/home.aspx">Gallup Opinion Polls</a></li>
<li><a href="http://goodnewsplanet.com">Good News Planet</a></li>
<li><a href="https://www.brainyquote.com/topics/motivational">Motivational Quotes of the Day</a></li>
<li><a href="https://www.huffpost.com/impact/topic/good-news">Huffpost Good News</a></li>
<li><a href="https://www.nbcnews.com/better">NBC: BETTER</a></li>
</ul>
</div>
<div id="news_sources">
<span class="rd_heading">NEWS SOURCES:</span><br>
<ul>
<li><a href="paper.html">USA/World Newspapers</a></li>
<li><a href="top10pap.html">Top 10 U.S. Newspapers</a></li>
<li><a href="https://www.newseum.org/todaysfrontpages/">Today's Front Pages</a></li>
<li><a href="https://politicalcartoons.com/">Cagle's Political Cartoons</a></li>
<br>
<a href="https://abcnews.go.com/">ABC</a> |
<a href="https://www.afp.com/en">AFP</a> |
<a href="https://apnews.com/hub/ap-top-news">AP</a> |
<a href="https://www.axios.com/">Axios</a> |
<a href="https://www.bbc.com/news">BBC</a> |
<a href="https://www.bing.com/news">Bing</a> |
<a href="https://www.theblaze.com/">Blaze</a> |
<a href="https://www.bloomberg.com/">Bloomberg</a> |
<a href="https://www.bostonglobe.com/">Boston Globe</a> |
<a href="https://www.breitbart.com/">Breitbart</a> |
<a href="https://www.c-span.org/">C-SPAN</a> |
<a href="https://www.cbc.ca/news">CBC</a> |
<a href="https://www.cbsnews.com/">CBS</a> |
<a href="https://chicago.suntimes.com/">Chicago Sun-Times</a> |
<a href="https://www.chicagotribune.com/">Chicago Tribune</a> |
<a href="https://www.cnn.com/">CNN</a> |
<a href="https://www.ctvnews.ca/">CTV</a> |
<a href="https://www.thedailybeast.com/">Daily Beast</a> |
<a href="https://www.drudgereport.com/">Drudge Report</a> |
<a href="https://www.excite.com/news">Excite</a> |
<a href="https://www.forbes.com/">Forbes</a> |
<a href="https://www.foxnews.com/">FOX </a> |
<a href="https://news.google.com/">Google</a> |
<a href="https://www.theguardian.com/us">Guardian</a> |
<a href="https://www.huffpost.com/">Huffington Post</a> |
<a href="https://www.latimes.com/">LA Times</a> |
<a href="https://www.msn.com/en-us/">MSN</a> |
<a href="https://www.msnbc.com/">MSNBC</a> |
<a href="mideastnews.html">Middle East News</a> |
<a href="https://www.nbcnews.com/">NBC</a> |
<a href="https://www.npr.org/sections/news">NPR</a> |
<a href="https://www.nydailynews.com/">New York Daily News</a> |
<a href="https://www.nytimes.com/">New York Times</a> |
<a href="https://www.newsclusters.com">News Clusters</a> |
<a href="https://www.newsnow.co.uk/h/">NewsNow</a> |
<a href="https://www.newsweek.com/">Newsweek</a> |
<a href="https://www.oann.com/">OANN</a> |
<a href="https://www.pbs.org/newshour/">PBS NewsHour</a> |
<a href="https://www.reuters.com/">Reuters</a> |
<a href="https://www.sfchronicle.com/">San Francisco Chronicle</a> |
<a href="https://news.sky.com/">Sky News</a> |
<a href="https://time.com/">Time</a> |
<a href="https://www.today.com/">Today</a> |
<a href="https://www.upi.com/">UPI</a> |
<a href="https://www.usatoday.com/">USA Today</a> |
<a href="https://wn.com/">WN.com</a> |
<a href="https://www.wsj.com/">Wall Street Journal</a> |
<a href="https://www.washingtontimes.com/">Wash. Times</a> |
<a href="https://www.washingtonpost.com/">Wash. Post</a> |
<a href="http://www.wopular.com/home/full_news_rack">Wopular</a> |
<a href="http://www.worldpronews.com/">WorldProNews</a> |
<a href="https://news.yahoo.com/">Yahoo</a>
</div>
<div id="gas_and_oil_prices">
<span class="rd_heading">CURRENT GAS & OIL PRICES:</span><br>
<a href="https://gasprices.aaa.com/">AAA: Gas Prices</a> |
<a href="https://gasprices.aaa.com/">AAA: Fuel Cost Calculator</a> |
<a href="https://www.eia.gov/state/">DOE: Energy Historical Data</a> |
<a href="https://www.eia.gov/petroleum/gasdiesel/">DOE: Gasoline/Diesel Fuel Update</a> |
<a href="https://www.eia.gov/dnav/pet/pet_move_impcus_a2_nus_ep00_im0_mbbl_m.htm">DOE: Sources of Crude Oil</a> |
<a href="https://www.eia.gov/petroleum/weekly/">DOE: This Week In Petroleum</a> |
<a href="https://www.gasbuddy.com/">GasBuddy: Gas Prices by Zip Code</a> |
<a href="https://auto.howstuffworks.com/fuel-efficiency/fuel-consumption/gas-price.htm">How Gas Prices Work</a> |
<a href="https://www.mapquest.com/search/results?query=Gas">Mapquest Gas Prices</a> |
<a href="https://oilprice.com/">Oil Price.com</a> |
<a href="https://www.gasbuddy.com/gaspricemap">USA Gas Prices Map</a>
</div>
<div id="us_government">
<span class="rd_heading">GOVERNMENT & ECONOMY:</span><br>
<ul>
<li><a href="https://www.usa.gov/Contact/Elected.shtml">Contact USA Elected Officials</a></li>
<li><a href="https://www.xe.com/">Currency Exchange Rates</a></li>
<li><a href="https://www.data.gov/">Government Stats</a></li>
<li><a href="jobsearch.html">Job Search Resources</a></li>
<li><a href="https://www.defense.gov/">Military Information</a></li>
<li><a href="https://www.gasbuddy.com/gaspricemap">USA Gas Price Map</a></li>
<li><a href="http://www.city-data.com/">U.S. Cities Guide</a></li>
<li><a href="https://www.usdebtclock.org/">U.S. Debt Clock: Real Time</a></li>
<li><a href="https://www.treasurydirect.gov/govt/reports/pd/histdebt/histdebt.htm">U.S. Debt & Historical Data</a></li>
<li><a href="https://www.fisc.uscourts.gov/public-filings">U.S. FISC Public Filings</a></li>
<li><a href="https://www.usa.gov/">U.S. Gov't Sites</a></li>
<li><a href="https://www.house.gov/representatives">U.S. Representatives</a></li>
<li><a href="https://www.senate.gov/senators/states.htm">U.S. Senators</a></li>
<li><a href="https://www.fdic.gov/bank/individual/failed/banklist.html">Failed Banks</a></li>
<li><a href="https://www.census.gov/popclock/">U.S. / World Pop Clock</a></li>
<li><a href="https://www.vitalrec.com/">Vital Records</a></li>
</ul>
</div>
<div id="features">
<span class="rd_heading">FEATURES:</span><br>
<ul>
<li><a href="https://finance.yahoo.com/q?s=%5edji&d=t">Current Dow Jones Avg.</a></li>
<li><a href="https://www.bloomberg.com/energy">Crude Oil | Energy Prices</a></li>
<li><a href="https://money.cnn.com/data/commodities/">Commodities Futures</a></li>
<li><a href="https://gasprices.aaa.com/">Daily Fuel Gauge Report</a></li>
<li><a href="https://www.uexpress.com/dearabby">Dear Abby</a></li>
<li><a href="https://www.drudgereport.com/">Drudge Report</a></li>
<li><a href="https://finance.yahoo.com/topic/stock-market-news">Market Update and Charts</a></li>
<li>Comics <a href="https://www.washingtonpost.com/entertainment/comics/">1</a> |
<a href="https://www.gocomics.com/?ref=comics">2</a> |
<a href="https://sports.yahoo.com/">Sports</a></li>
<li><a href="https://news.google.com/news/section?cf=all&pz=1&topic=m&siidp=94b96873970b99267fa5df53b7ae8722a3ea&ict=ln">Health</a> |
<a href="https://news.google.com/topics/CAAqJggKIiBDQkFTRWdvSUwyMHZNRGRqTVhZU0FtVnVHZ0pWVXlnQVAB">Tech</a> |
<a href="https://news.google.com/topics/CAAqJggKIiBDQkFTRWdvSUwyMHZNRFp0Y1RjU0FtVnVHZ0pWVXlnQVAB">Science</a></li>
<li><a href="https://finance.yahoo.com">Finance</a> |
<a href="https://www.yahoo.com/politics">Politics</a> |
<a href="https://news.yahoo.com/">Popular</a></li>
<li><a href="https://ew.com/">Entertainment</a></li>
<li>Obituaries <a href="https://www.legacy.com/">1</a> |
<a href="http://www.obituaries.com/ns/obituariescom/obits.aspx">2</a> |
<a href="https://www.obitlinkspage.com/">3</a></li>
<li><a href="https://www.weather.gov/">Weather</a></li>
</ul>
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<li><a href="https://www.howstuffworks.com/">How Stuff Works</a></li>
<li><a href="https://www.ehow.com/how_2049722_clean-anything.html">How To Clean Anything</a></li>
<li><a href="https://www.infoplease.com/">Information Please</a></li>
<li><a href="https://support.microsoft.com/">Microsoft Support</a></li>
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<li><a href="https://www.bartleby.com/141/index.html">Elements of Style</a></li>
<li><a href="https://www.grammarly.com">Grammarly</a></li>
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<li><a href="http://jacklynch.net/Writing/links.html">Resources for Writers</a></li>
<li><a href="https://online.maryville.edu/online-bachelors-degrees/liberal-studies/ultimate-guide-to-writing-styles/">Ultimate Guide to Writing Styles</a></li>
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<li><a href="https://www.coffeebreakarcade.com/" rel="nofollow">Coffee Break Arcade</a></li>
<li><a href="https://copykat.com/" rel="nofollow">CopyKat Recipes</a></li>
<li><a href="https://www.crazyfads.com/" rel="nofollow">Crazy Fads</a></li>
<li><a href="https://www.crazygames.com/" rel="nofollow">CrazyGames.com</a></li>
<li><a href="crosswrd.html">Crosswords</a></li>
<li>Daily Comics: <a href="https://www.washingtonpost.com/entertainment/comics/" rel="nofollow">1</a> | <a href="https://www.gocomics.com/?ref=comics" rel="nofollow">2</a></li>
<li><a href="https://www.baronbarclay.com/frank-stewarts-daily-bridge-column/" rel="nofollow">Daily Bridge Column</a></li>
<li><a href="https://gasprices.aaa.com/" rel="nofollow">Daily Fuel Gauge Report</a></li>
<li><a href="https://www.pepysdiary.com/" rel="nofollow">Diary of Samuel Pepys</a></li>
<li><a href="https://download.cnet.com/" rel="nofollow">Download Resources</a></li>
<li><a href="https://www.earthcam.com/" rel="nofollow">Earthcam</a></li>
<li><a href="features.html">Features Page</a></li>
<li><a href="https://fibble.xyz/" rel="nofollow">Fibble</a></li>
<li>Free Online Games: <a href="https://www.agame.com/" rel="nofollow">1</a> | <a href="https://www.games.co.uk/" rel="nofollow">2</a></li>
<li><a href="free.html">Free Stuff</a></li>
<li><a href="https://garden.org/">Gardening Guide</a></li>
<li><a href="https://www.grand-illusions.com/" rel="nofollow">Grand Illusions</a></li>
<li><a href="https://www.guinnessworldrecords.com/" rel="nofollow">Guinness World Records</a></li>
<li><a href="sports1.html">Hobbies and Recreation</a></li>
<li><a href="https://pun.me" rel="nofollow">Jokes and Puns</a></li>
<li><a href="https://www.nytimes.com/column/best-of-late-night" rel="nofollow">Late Night Jokes</a></li>
<li><a href="https://laffgaff.com/" rel="nofollow">LaffGaff: Short Funny Jokes</a></li>
<li><a href="https://www.lumosity.com/" rel="nofollow">Luminosity Brain Games</a></li>
<li><a href="https://classic-mahjong.com/" rel="nofollow">Mahjong</a></li>
<li><a href="https://zone.msn.com/en-us/home" rel="nofollow">MSN Games</a></li>
<li><a href="https://www.minigames.com/" rel="nofollow">MiniGames.com</a></li>
<li><a href="https://www.nutaku.com/" rel="nofollow">Nutaku</a></li>
<li><a href="https://www.names.org/" rel="nofollow">Names.org</a></li>
<li><a href="http://www.oxymoronlist.com" rel="nofollow">Oxymoron List</a></li>
<li><a href="http://www.playfg.com" rel="nofollow">Play Flash Games</a></li>
<li><a href="https://poems.com/" rel="nofollow">Poetry Daily</a></li>
<li><a href="https://www.plough.com/en/subscriptions/daily-prayer">Prayer of the Day</a></li>
<li><a href="https://poki.com/" rel="nofollow">Poki</a></li>
<li><a href="http://www.publicradiofan.com/" rel="nofollow">PublicRadioFan.com</a></li>
<li><a href="https://radio-locator.com/" rel="nofollow">Radio-Locator</a></li>
<li><a href="https://robinwords.com" rel="nofollow">RobinWords</a></li>
<li><a href="http://www.literarygenius.info/a2-shakespeare-insult-generator.htm" rel="nofollow">Shakespearean Insulter</a></li>
<li><a href="https://www.websudoku.com/" rel="nofollow">Sudoku Puzzles</a></li>
<li><a href="https://online-solitaire.com/refdesk" rel="nofollow">Solitaire - Refdesk Edition</a></li>
<li><a href="http://www.terrafly.com/" rel="nofollow">TerraFly Satellite Images</a></li>
<li><a href="https://dmarie.com/timecap/" rel="nofollow">Time Capsule</a></li>
<li><a href="https://www.nbc.com/the-tonight-show/photos/monologue-jokes" rel="nofollow">Tonight Show Jokes</a></li>
<li><a href="https://www.top10zen.com/" rel="nofollow">Top10Zen</a></li>
<li><a href="https://www.truthorfiction.com/" rel="nofollow">TruthOrFiction.com</a></li>
<li><a href="https://www.visibleearth.nasa.gov/">Visible Earth</a></li>
<li><a href="https://www.usinflationcalculator.com/" rel="nofollow">What's a Dollar Worth?</a></li>
<li><a href="https://www.nytimes.com/games/wordle/" rel="nofollow">Wordle</a></li>
<li><a href="https://www.word-square.com/" rel="nofollow">Word Square</a></li>
<li><a href="http://www.fourmilab.to/yoursky" rel="nofollow"/>Your Sky</a></li>
</ul>
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<!-- SOTD START -->
<a href="https://www.nytimes.com/2023/11/28/books/review/best-books-2023.html">New York Times: The 10 Best Books of 2023</a>
<p>
The editors of The Times Book Review choose the best fiction and nonfiction titles this year.
<!-- SOTD END -->
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<td width="40%" align="left" class="small_text"><b><a href="/archive/">Site of the Day<br> Archive</a></b></td>
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<td width="40%" align="left"><b><a href="/archive/fact/">Fact of the Day<br>Archive</a></b></td>
<td width="60%" align="left"><b><a href="https://www.factretriever.com/">Random Fact of the Day</a></b></td>
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<td width="40%" align="left"><b><a href="/archive/thought/">Thought of the Day<br>Archive</a></b></td>
<td width="60%" align="left"><b><a href="https://www.brainyquote.com/topics/motivational">Motivational Quotes of the Day</a></b></td>
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<span class="rd_heading">BOOK OF THE MONTH</span>
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<p><b>DEATH IN HOLY ORDERS</b><br>By: by Charles Keating, P. D. James, et al., 2001</p>
<p>
We love murder mystery books, but too many seem trivial: a cute plot and setting, but no evidence that the author was deeply involved in creating a special reading experience. Discovering P.D. James changed that for us. She wrote a dozen books in her life, published more than 20 years ago. Her books are wonderful! We found them clear, erudite, and involving without being silly. They are generally set in the southeast part of England. We just finished DEATH IN HOLY ORDERS and strongly recommend it, and all others by P.D. James.
</p>
<p>
<span class="small_text"><b><a href="/archive/book/">Book of the Month Archive</a></b></span>
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<!-- Article of the Day by TheFreeDictionary.com -->
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<span class="rd_heading">MORE THIS DAY IN HISTORY:</span><br>
<a href="https://apnews.com/hub/today-in-history">Associated Press</a> |
<a href="https://news.bbc.co.uk/onthisday/">BBC</a> |
<a href="https://www.history.com/this-day-in-history">History Channel</a> |
<a href="https://www.historynet.com/today-in-history">HistoryNet</a> |
<a href="https://www.onthisday.com/">OnThisDay.com</a> |
<a href="https://www.infoplease.com/dayinhistory">InfoPlease</a> |
<a href="https://www.loc.gov/item/today-in-history/may-04/">Library of Congress</a> |
<a href="https://www.nytimes.com/learning/general/onthisday/index.html">New York Times</a>
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<!-- Today's Birthday by TheFreeDictionary.com -->
<span class="rd_heading">TODAY'S BIRTHDAY:</span> <span class="small_text">provided by <a href="https://www.thefreedictionary.com">The Free Dictionary</a> <a href="https://www.thefreedictionary.com/_/archive.htm">Archive >></a></span>
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<a href="https://apnews.com/hub/today-in-history">AP</a> |
<a href="http://www.famousbirthdays.com/today.cgi">Famous Birthdays</a> |
<a href="https://www.infoplease.com/birthday">InfoPlease</a> |
<a href="https://www.onthisday.com/today/birthdays.php">OnThisDay.com</a>
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<span class="rd_heading">TODAY'S PICTURES:</span><br>
<a href="https://www.arizonahighways.com/category/photo-day">Arizona Highways</a> |
<a href="https://apod.nasa.gov/apod/astropix.html">Astronomy Picture of the Day</a> |
<a href="https://www.ssec.wisc.edu/data/comp/latest_cmoll.gif">Earth's Current Temps/Clouds</a> |
<a href="https://go.nasa.gov/3Aai8h4">Earth Observatory: Image of the Day</a> |
<a href="https://epod.usra.edu/">Earth Science Picture of the Day</a> |
<a href="https://www.instagram.com/gopro/">GoPro</a> |
<a href="https://mars.nasa.gov/mer/index.html">Latest Mars Images</a> |
<a href="https://www.nasa.gov/mission_pages/cassini/main/index.html">Latest Saturn Images</a> |
<a href="https://epic.gsfc.nasa.gov">NASA EPIC::DSCOVR Daily Satellite Images</a> |
<a href="https://www.nasa.gov/multimedia/imagegallery/">NASA Image of the Day</a> |
<a href="https://www.visibleearth.nasa.gov/">NASA Visible Earth</a> |
<a href="https://www.nationalgeographic.com/photography/photo-of-the-day/">Nat. Geographic: Photo of the Day (subscription)</a> |
<a href="https://www.nesdis.noaa.gov/real-time-imagery/imagery-collections/image-of-the-day">NOAA Image of the Day</a> |
<a href="https://www.atoptics.co.uk/opod.htm">Optics Picture of the Day</a> |
<a href="https://www.reuters.com/news/pictures">Reuters Pictures of the Week</a> |
<a href="https://www.telegraph.co.uk/news/pictures/">Telegraph Pictures of the Day (subscription)</a> |
<a href="https://time.com/section/lightbox/">TIME: Photography</a> |
<a href="https://time.com/section/lightbox/">TIME: LightBox</a> |
<a href="https://news.yahoo.com/tagged/photos/">Top News Photos: Yahoo</a> |
<a href="http://www.washingtonpost.com/wp-dyn/content/photo/?nav=globetop">Wash. Post Day in Photos</a> |
<a href="https://www.wpc.ncep.noaa.gov/noaa/noaa.gif">Weather Forecast Image (NOAA)</a> |
<a href="https://www.nesdis.noaa.gov/">Weather Picture of the Day</a> |
<a href="https://www.earthcam.com/">Webcam Index</a>
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<span class="rd_heading">WORD OF THE DAY:</span>
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<li><a href="https://www.wordsmith.org/words/today.html">A.Word.A.Day</a></li>
<li><a href="https://www.infoplease.com/analogies">Analogy of the Day</a></li>
<li><a href="https://www.factmonster.com/schoolword">Daily Word Quiz</a> </li>
<li><a href="https://www.dictionary.com/e/word-of-the-day/">Dictionary.com Word of the Day</a></li>
<li><a href="https://www.merriam-webster.com/word-of-the-day">Merriam-Webster</a></li>
<li><a href="https://www.nytimes.com/column/learning-word-of-the-day">New York Times</a></li>
<li><a href="https://www.merriam-webster.com/word-games">Word Game of the Day</a></li>
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<span class="rd_heading">DAILY DIVERSIONS:</span><br>
<a href="https://99u.adobe.com/">99U.com</a> |
<a href="https://games.aarp.org/">AARP Games Page</a> |
<a href="https://aeon.co/">Aeon</a> |
<a href="https://aldaily.com/">Arts & Letters Daily</a> |
Book Review: <a href="https://www.barnesandnoble.com/review/">1</a> - <a href="https://www.bookforum.com/">2</a> |
<a href="https://stayingsharp.aarp.org/about/brain-health/games/">Brain Games</a> |
<a href="https://www.internet4classrooms.com/brain_teasers.htm">Brain Teasers</a> |
<a href="https://www.chess.com/">Chess Games</a> |
<a href="https://www.yourclassical.org/programs/composers-datebook/episodes">Composers Datebook</a> |
Comics: <a href="https://www.washingtonpost.com/entertainment/comics/">1</a> - <a href="https://www.gocomics.com/?ref=comics">2</a> |
<a href="crosswrd.html">Crosswords</a> |
<a href="https://www.cfa.harvard.edu/skyreport">Current Sky Information</a> |
<a href="quote.html">Daily Almanac</a> |
<a href="https://cryptograms.puzzlebaron.com/">Daily Cryptogram</a> |
<a href="http://www.threadbender.com/">Daily Cryptoquote</a> |
<a href="https://download.cnet.com/">Daily Download</a> |
<a href="https://haiku.mannlib.cornell.edu/">Daily Haiku</a> |
<a href="https://www.rd.com/jokes/">Daily Humor: Reader's Digest</a> |
<a href="http://www.jigzone.com/puzzles/">Daily Jigsaw Puzzle</a> |
<a href="https://thejigsawpuzzles.com">Digital Jigsaw Puzzles</a> |
<a href="https://fun.chicagotribune.com/game/tca-jumble-daily">Daily Word Jumble</a> |
<a href="https://www.dailywritingtips.com/category/misused-words/">Daily Writing Tips</a> |
<a href="http://www.scopesys.com/today/">Events, Births, History</a> |
<a href="http://www.factslides.com/">FactSlides: Random Facts</a> |
<a href="https://www.thefamouspeople.com/">Famous People Born Today</a> |
<a href="https://www.gamesforthebrain.com/">Games for the Brain</a> |
<a href="http://www.googlesightseeing.com/">Google Sightseeing</a> |
<a href="horoscps.html">Horoscope Resources</a> |
<a href="https://www.nytimes.com/column/best-of-late-night">Late Night Jokes</a> |
<a href="https://www.lotteryusa.com/">Lottery Results</a> |
Medical News: <a href="https://www.medpagetoday.com/">1</a> - <a href="https://www.medicaldaily.com/">2</a> |
<a href="https://www.mix.com">Mix (Formerly StumbleUpon)</a> |
Moon Phases
<a href="https://www.moonconnection.com/moon_phases_calendar.phtml">1</a> -
<a href="https://moonphases.org/">2</a> |
<a href="https://www.brainyquote.com/topics/motivational">Motivational Quotes of the Day</a> |
<a href="https://www.imdb.com/">Movies</a> |
<a href="https://www.netflix.com/">Netflix</a> |
<a href="https://www.almanac.com/">Old Farmer's Almanac</a> |
<a href="https://poems.com/">Poetry Daily</a> |
<a href="https://www.brainyquote.com/quote_of_the_day">Quote of the Day</a> |
<a href="https://en.wikipedia.org/wiki/Marq_de_Villiers">Random Wikipedia Article</a> |
<a href="https://www.sciencedaily.com/">Science Daily</a> |
<a href="https://scitechdaily.com/">SciTech Daily Review</a> |
<a href="https://www.websudoku.com/">Sudoku Puzzles</a> |
<a href="https://www.almanac.com/astronomy/sun-rise-and-set">Sun/Moon Rise & Set</a> |
<a href="https://theawesomedaily.com/">The Awesome Daily</a> |
<a href="https://www.thisdayinmusic.com/">This Day In Music</a> |
<a href="http://www.thisdayincountrymusic.com/">This Day In Country Music</a> |
<a href="http://www.todayifoundout.com/">Today I Found Out</a> |
<a href="https://earthquake.usgs.gov/learn/today/">Today In Earthquake History</a> |
<a href="https://www.loc.gov/item/today-in-history/may-04/">Today in History</a> |
<a href="https://www.allaboutjazz.com/php/facts.php">Today In Jazz History</a> |
<a href="http://www.eastoftheweb.com/cgi-bin/top_scores.pl?game=cryptoquote">Today's Cryptoquote</a> |
<a href="https://earthsky.org/tonight">Tonight's Sky</a> |
<a href="https://www.barnesandnoble.com/b/books/_/N-1fZ29Z8q8">Top 100 Bestseller Books</a> |
<a href="http://www.ebizmba.com/articles/most-popular-websites">Top Most Popular Websites</a> |
<a href="http://www.ebizmba.com/articles/social-networking-websites">Top Social Networking Sites</a> |
<a href="https://www.tvguide.com/">TV</a> |
<a href="https://www.nytimes.com/games/wordle/">Wordle</a> |
<a href="http://www.fourmilab.to/yoursky/">Your Sky</a> |
<a href="#fun">Just For Fun >></a>
</div>
<div id="daily_potpourri">
<span class="rd_heading">TODAY'S POTPOURRI:</span><br>
• Daily Trivia: <a href="https://www.randomtriviagenerator.com/">Random Trivia Generator</a> |
<a href="https://www.triviatoday.com/">Trivia Today</a><br>• Computer Virus List: <a href="https://www.mcafee.com/enterprise/en-us/threat-center.html">McAfee</a> |
<a href="https://www.broadcom.com/support/security-center">Symantec</a> |
<a href="https://www.trendmicro.com/en_us/forHome.html">Trend Micro</a><br>
• Health: <a href="https://abcnews.go.com/health">ABC</a> |
<a href="https://www.bbc.co.uk/news/health">BBC</a> |
<a href="https://www.medpagetoday.com/">Breaking Medical News</a> |
<a href="https://www.cnn.com/health">CNN</a> |
<a href="https://www.webmd.com/news/">WebMD</a> |
<a href="https://www.yahoo.com/lifestyle/tagged/health">Yahoo</a><br>
• Science: <a href="https://news.yahoo.com/science/">AP</a> |
<a href="https://www.bbc.co.uk/news/science_and_environment">BBC</a> |
<a href="https://earthsky.org/">Earth & Sky</a> |
<a href="https://science.nasa.gov/">NASA</a> |
<a href="https://www.nbcnews.com/tech-media">NBCNews</a> |
<a href="https://www.newscientist.com/">NewScientist.com</a> |
<a href="https://news.yahoo.com/science/">Yahoo</a> |
<a href="https://www.space.com">Space.com</a><br>
• Technology: <a href="https://abcnews.go.com/technology">ABC</a> |
<a href="https://www.cnet.com/">CNET</a> |
<a href="https://www.cnn.com/business/tech">CNN</a> |
<a href="https://www.infoworld.com/">InfoWorld</a> |
<a href="https://www.pcmag.com/">PC Magazine</a> |
<a href="https://www.pcworld.com/">PC World</a> |
<a href="https://www.usatoday.com/tech/">USA Today</a> |
<a href="https://news.google.com/news/section?cf=all&pz=1&topic=tc&siidp=6ff49a420e5b2b59f58b98686ea8d58f6f46&ict=ln">Yahoo</a> |
<a href="https://www.zdnet.com">ZDNet</a> <br>• Misc: <a href="https://answers.yahoo.com/">Yahoo Answers</a> |
<a href="https://www.onthisday.com/today/birthdays.php">Born on Today</a> |
<a href="https://www.bestcrosswords.com/">Crossword</a> |
<a href="https://www.greatday.com/motivate/">Daily Motivator</a> |
<a href="https://www.epic.org/">EPIC</a> |
<a href="http://www.dailygood.org">Good News</a> |
<a href="https://www.usatoday.com/life/music/">Music</a> |
<a href="https://scitechdaily.com/">SciTech Review</a> |
<a href="https://www.dynatrace.com/platform/digital-experience-monitoring/?vehicle_name=internetpulse.net">Internet Health Report</a> |
</div>
<section id="test_prep_wrapper" class="no_mobile">
<div id="test_prep">
<span class="rd_heading">TEST PREPARATION:</span><br>
<ul>
<li><a href="https://asvabadvantage.com/asvab-practice-test/">ASVAB Prep</a></li>
<li><a href="https://dlabprep.com/">DLAB Prep</a></li>
<li><a href="https://www.efficientlearning.com/">CPA/CMA/CFA Test Prep</a></li>
<li><a href="https://cna.plus/">Free CNA Exam Cram Practice Test</a></li>
<li><a href="http://www.princetonreview.com/grad/free-gre-practice-test.aspx">Free GRE Online Practice Test</a></li>
<li><a href="http://www.princetonreview.com/grad/gre-test-preparation.aspx">GRE Test Prep</a></li>
<li><a href="https://www.getprepped.com/practice-lsat-sample-questions/">LSAT Sample Questions</a></li>
<li><a href="https://www.mcat-prep.com/mcat-sample-questions/">MCAT Prep</a></li>
<li><a href="https://www.pearsonassessments.com/graduate-admissions/mat/about.html?tab=preparing-for-the-mat#preparing-for-the-mat">MAT Prep</a></li>
<li><a href="http://www.number2.com/index.cfm?s=4zg5qaSrlPSQCYDbIy4vMvOT">Free Online Test Prep</a></li>
<li><a href="https://www.khanacademy.org/sat">Official SAT Practice</a></li>
<li><a href="https://www.blinetestprep.com/">Free SAT Prep</a></li>
<li><a href="https://sat.collegeboard.org/practice">SAT Preparation</a></li>
<li><a href="https://collegereadiness.collegeboard.org/sat/practice/full-length-practice-tests">SAT Practice Tests</a></li>
<li><a href="https://collegereadiness.collegeboard.org/sat/practice">SAT Preparation Center</a></li>
<li><a href="https://www.visualthesaurus.com/bee/">Spelling Bee</a></li>
<li><a href="https://www.testprepreview.com/">Test Prep Review</a></li>
<li><a href="https://www.nytimes.com/column/learning-news-quiz">Weekly News Quiz: NYT</a></li>
</ul>
</div>
</section>
<!-- AD_START -->
<div id="center_ad">
<center>
<!-- /218243714/300x250_center_2 -->
<div id='div-gpt-ad-1499952499353-0' class="no_border" style="height:270px; width:320px;">
<script>
//googletag.cmd.push(function() { googletag.display('div-gpt-ad-1499952499353-0'); });
</script>
</div>
</center>
</div>
<!-- AD_STOP -->
<section id="rd_center_lower" class="no_mobile"><!-- intentionally nested in rd_center -->
<div id="facts_search_desk">
<div class="title_div"><span class="title_span">Facts Search Desk</span></div>
<div id="facts_search_desk_content">
<b>Content Resources:</b>
<table width=100%>
<tr>
<td>
<form method=get action="https://news.search.yahoo.com/search?p=">
<span class="small_text">Reuters/AP Headlines</span><br>
<input size=15 name=p>
<input type=submit value=Go>
</form>
</td>
<td>
<form method="get" action="https://www.factmonster.com/search.php3" target="_blank">
<span class="small_text">Fact Monster</span><br>
<input size=15 name="query">
<input type=submit value=Go>
</form>
</td>
</tr>
</table>
<table width=100%>
<tr>
<td valign=top class="small_text">
<!-- BEGIN WEBOPEDIA SEARCH -->
<div style="font-family:Arial,Helvetica,Verdana,sans-serif;font-size:12px">
<img border="0" src="webopedia.png" width="100">
<form action="https://www.webopedia.com/" method="GET">
<input type="text" size="20" name="s" maxlength="512" placeholder="Enter a tech term...">
<input type="submit" value="Go!" name="submit">
</form>
</div>
<!-- END WEBOPEDIA SEARCH -->
</td>
<td width=50% class="small_text">
<form method="get" action="https://search.nlm.nih.gov/medlineplus/query" target="_self" id="form1" name="form1">
Medical Dictionary<br>
<input name="MAX" type="hidden" value="500">
<input name="SERVER1" type="hidden" value="server1">
<input name="SERVER2" type="hidden" value="server2">
<input name="PARAMETER" type="text" size="15" value="">
<input name="DISAMBIGUATION" type="hidden" value="true">
<input type="hidden" name="FUNCTION" value="search">
<input type="submit" name="submit" value="Go">
</form>
</td>
</tr>
</table>
<table width=100%>
<tr>
<td width="50%" valign="top" class="small_text">
• <a href="https://www.dictionary.com/">Dictionary.com</a><br>
• <a href="https://www.nolo.com/dictionary">Law Dictionary</a><br>
• <a href="https://translate.google.com/">Google Translate</a><br><br>
</td>
<td width=50% valign="top" class="small_text">
<form method="GET" action="https://www.bartleby.com/writing/search">
Bartleby.com<br>
<INPUT TYPE=text SIZE=19 MAXLENGTH=50 NAME="query">
<INPUT TYPE=submit NAME="Submit" VALUE="Go">
</form>
</td>
</tr>
</table>
<b>Translation Dictionaries</b> ( one word only, e.g. fact )<br>
<table width="100%">
<tr>
<td width="50%" valign="top" class="small_text">
<form action="https://wordreference.com/es/translation.asp" AUTOCOMPLETE="off" method="GET" name="tenes">
English to Spanish<br>
<INPUT NAME="tranword" TYPE="text" SIZE="13" VALUE="">
<INPUT TYPE="submit" VALUE="Go">
</form>
</td>
<td width="50%" class="small_text">
<form action="https://www2.dict.cc/?l=d" style="margin:0px;" method="get">
English to German<br>
<INPUT TYPE="TEXT" NAME="s" id="sinp" MAXLENGTH="100" SIZE="13" VALUE="">
<INPUT TYPE="SUBMIT" NAME="btngo" VALUE="Go" CLASS="inp1">
</form>
</td>
</tr>
</table>
<table width="100%">
<tr>
<td width="50%" valign="top" class="small_text">
<form action="https://wordreference.com/it/translation.asp" AUTOCOMPLETE="off" method="get" name="tenit">
English to Italian<br>
<INPUT NAME="enit" TYPE="text" SIZE="13" VALUE="">
<INPUT TYPE=submit VALUE="Go">
</form>
</td>
<td width="50%" class="small_text">
<form action="https://wordreference.com/fr/translation.asp" AUTOCOMPLETE="off" method="get" name="tenfr">
English to French<br>
<input type=text size=13 name="enfr">
<input type="submit" value="Go">
</form>
</td>
</tr>
</table><br>
<a name="media_fact_check"></a>
<span class="rd_heading">MEDIA FACT CHECKS:</span><br>
<a href="https://www.aim.org/">Accuracy In Media</a> -
<a href="https://fair.org/">Fair</a> -
<a href="https://www.mediamatters.org/studies">Media Matters</a> -
<a href="https://www.politifact.com/">Politifact</a> -
<a href="https://www.snopes.com/">Snopes</a><br><br>
<a name="search"></a>
<span class="rd_heading">SEARCH ENGINES:</span><br>
<a href="https://www.ask.com/">Ask.com</a> -
<a href="https://www.bing.com/">Bing</a> -
<a href="https://www.dogpile.com/">Dogpile</a> -
<a href="https://duckduckgo.com">DuckDuckGo</a> -
<a href="https://www.google.com/">Google</a> -
<a href="https://www.hotbot.com/">HotBot</a> -
<a href="https://www.startpage.com/">ixquick</a> -
<a href="https://www.looksmart.com/">Looksmart</a> -
<a href="https://pipl.com/">Pipl</a> -
<a href="https://startpage.com">Startpage</a> -
<a href="https://search.yahoo.com/">Yahoo!</a> -
<a href="newsrch.html">More >></a>
</div>
</div>
<div id="current_news_weather_business_sports">
<div class="title_div"><span class="title_span"><a name="current">Current News / Weather / Business / Sports</a></span></div>
<div id="current_news_weather_business_sports_content">
• <b>Headlines:</b>
<a href="https://www.1stheadlines.com/"> 1st Headlines</a> -
<a href="https://apnews.com/hub/ap-top-news">AP Wire</a> -
<a href="https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=b&ict=ln">Business</a> -
<a href="https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=e&ict=ln&siidp=851d9d0dc23b1f3f2d05f8274320e9f4d645">Entertainment</a> -
<a href="https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=m&ict=ln&siidp=851d9d0dc23b1f3f2d05f8274320e9f4d645">Health</a> -
<a href="https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=snc&ict=ln&siidp=851d9d0dc23b1f3f2d05f8274320e9f4d645">Science</a> -
<a href="https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=s&ict=ln&siidp=851d9d0dc23b1f3f2d05f8274320e9f4d645">Sports</a> -
<a href="https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=tc&ict=ln&siidp=851d9d0dc23b1f3f2d05f8274320e9f4d645">Technology</a> -
<a href="https://www.upi.com/">UPI Headlines</a> -
<a href="https://www.usatoday.com/news/">USA Today</a> -
<a href="https://news.google.com/news">More >></a>
<hr>
• <b>Weather:</b>
<a href="https://www.accuweather.com/"> AccuWeather Service</a> -
<a href="https://www.cnn.com/weather">CNN Weather</a> -
<a href="https://www.fema.gov/news-releases">FEMA News Releases</a> -
<a href="https://www.wunderground.com/maps/radar/current">Intellicast</a> -
<a href="https://www.nhc.noaa.gov/">National Hurricane Center</a> -
<a href="https://www.nws.noaa.gov/warnings.php">National Storm Warnings</a> -
<a href="https://www.weather.gov/">National Weather Service</a> -
<a href="https://www.usatoday.com/weather/">USA Today Weather</a> -
<a href="https://weather.com/">Weather Channel </a> -
<a href="https://www.yahoo.com/news/weather/">Yahoo! Weather</a> -
<a href="weath1.html">More >></a>
<hr>
• <b>News:</b>
<a href="https://abcnews.go.com/">ABC</a> -
<a href="https://www.afp.com/en">AFP</a> -
<a href="https://apnews.com/hub/ap-top-news">AP</a> -
<a href="https://www.bbc.co.uk/news">BBC</a> -
<a href="https://www.bloomberg.com/">Bloomberg</a>
<a href="http://www.cbc.ca/news/">CBC</a> -
<a href="https://www.cbsnews.com/">CBS</a> -
<a href="https://www.cnn.com/">CNN</a> -
<a href="https://www.ctvnews.ca/">CTV</a> -
<a href="https://www.dailysource.org/">DailySource</a> -
<a href="https://www.excite.com/news">Excite</a> -
<a href="https://www.foxnews.com/">FOX</a> -
<a href="https://news.google.com/">Google</a> -
<a href="https://www.msn.com/en-us/">MSN</a> -
<a href="https://www.msnbc.com/">MSNBC</a> -
<a href="mideastnews.html">Middle East News</a> -
<a href="https://www.npr.org/sections/news">NPR</a> -
<a href="https://www.nbcnews.com/">NBC</a> -
<a href="https://www.nytimes.com/">NYT</a> -
<a href="https://www.newsnow.co.uk/h/">NewsNow</a> -
<a href="https://www.reuters.com/">Reuters</a> -
<a href="https://news.sky.com/">Sky News</a> -
<a href="https://www.upi.com/">UPI</a> -
<a href="https://www.usatoday.com/news/">USA Today</a> -
<a href="https://wn.com/">WNN</a> -
<a href="https://www.wsj.com/">Wall Street Journal</a> -
<a href="https://www.washingtontimes.com/">Wash. Times</a> -
<a href="https://www.washingtonpost.com/">Wash. Post</a> -
<a href="https://news.yahoo.com/">Yahoo</a> -
<a href="features.html#news">More >></a>
<hr>
• <a name=papers><b>Newspapers:</b>
<a href="https://www.ajc.com/">Atlanta Journal-Constitution</a> -
<a href="https://archive.azcentral.com/arizonarepublic/">Arizona Republic</a> -
<a href="https://www.statesman.com/">Austin American-Statesman</a> -
<a href="http://www.sunspot.net/news/">Baltimore Sun</a> -
<a href="https://www.bostonglobe.com/">Boston Globe</a> -
<a href="https://chicago.suntimes.com/">Chicago Sun-Times</a> -
<a href="https://www.chicagotribune.com/">Chicago Tribune</a> -
<a href="https://www.csmonitor.com/">Christian Science Monitor</a> -
<a href="https://www.cleveland.com/plaindealer/">Cleveland Plain Dealer</a> -
<a href="https://www.dallasnews.com/">Dallas Morning News</a> -
<a href="https://www.denverpost.com/">Denver Post</a> -
<a href="https://www.freep.com/">Detroit Free Press</a> -
<a href="https://www.eastvalleytribune.com/">East Valley Tribune</a> -
<a href="https://www.chron.com/">Houston Chronicle</a> -
<a href="https://www.latimes.com/">Los AngelesTimes</a> -
<a href="https://www.miamiherald.com/">Miami Herald</a> -
<a href="https://www.startribune.com/">Minneapolis Star Tribune</a> -
<a href="https://www.nola.com/">New Orleans Times-Picayune</a> -
<a href="https://www.nj.com/starledger/">Newark Star-Ledger</a> -
<a href="https://www.nydailynews.com/">New York Daily News</a> -
<a href="https://nypost.com/">New York Post</a> -
<a href="https://www.nytimes.com/">New York Times</a> -
<a href="https://www.newsday.com/">Newsday</a> -
<a href="https://www.inquirer.com/">Philadelphia Inquirer</a> -
<a href="https://www.post-gazette.com/">Pittsburgh Post-Gazette</a> -
<a href="https://www.sandiegouniontribune.com/">San Diego Union-Tribune</a> -
<a href="https://www.sfgate.com/">San Francisco Chronicle</a> -
<a href="https://www.stltoday.com/">St. Louis Post-Dispatch</a> -
<a href="https://www.seattletimes.com/">Seattle Times</a> -
<a href="https://www.tampabay.com/">Tampa Bay Times</a> -
<a href="https://www.usatoday.com/">USA Today</a> -
<a href="https://www.washingtonpost.com/">Washington Post</a> -
<a href="https://www.washingtontimes.com/">Washington Times</a> -
<a href="paper.html">More >></a>
<hr>
• <b>International News:</b>
<a href="/asia.html#afghan">Afghanistan News</a> -
<a href="https://www.aljazeera.com/">Al Jazeera English</a> -
<a href="http://www.asahi.com/english/">Asahi Shimbun</a> -
<a href="http://www.asiatoday.com">Asia Today</a> -
<a href="http://www.canada.ca/news">Canada News</a> -
<a href="http://www.chinadaily.com.cn/">China Daily</a> -
<a href="https://www.haaretz.com/">Haaretz Daily</a> -
<a href="https://www.theglobeandmail.com/">Globe and Mail</a> -
<a href="http://www.guardian.co.uk/">Guardian</a> -
<a href="https://www.irishtimes.com/">Irish Times</a> -
<a href="https://tass.com/">Tass Russian News</a> -
<a href="https://www.japantimes.co.jp/">Japan Times</a> -
<a href="https://www.jpost.com/">Jerusalem Post</a> -
<a href="https://english.kyodonews.jp/login">Kyodo News</a> -
<a href="https://www.lemonde.fr/">Le Monde</a> -
<a href="http://www.dailystar.com.lb/">Lebanon Daily Star</a> -
<a href="http://www.timesonline.co.uk/?999">London Times</a> -
<a href="https://www.telegraph.co.uk/">London Telegraph</a> -
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<a href="https://www.smh.com.au/">Sydney Morn. Herald</a> -
<a href="https://theseoultimes.com/ST/index.html">Seoul Times</a> -
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<a href="https://www.worldpress.org/">World Press Review</a> -
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<a href="https://www.forbes.com/">Forbes</a> -
<a href="https://fortune.com/">Fortune</a> -
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<a href="https://www.kiplinger.com/">Kiplinger</a> -
<a href="https://www.msn.com/en-us/money/">MSN Money</a> -
<a href="https://www.morningstar.com/">Morningstar</a> -
<a href="https://www.fool.com/">Motley Fool</a> -
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<a href="https://www.redherring.com/">Red Herring</a> -
<a href="https://www.marketwatch.com/?showsmscrim=true">SmartMoney</a> -
<a href="https://www.thestreet.com/">TheStreet.com</a> -
<a href="http://www.marketwatch.com/news/default.asp?siteid=&avatar=seen">WSJ MarketWatch</a> -
<a href="http://www.headlinespot.com/subject/business/">More >></a>
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• <b>Sports:</b>
<a href="https://www.cbssports.com/">CBS Sports</a> -
<a href="https://www.espn.com/">ESPN</a> -
<a href="https://www.golfchannel.com/">Golf Channel</a> -
<a href="http://www.insidehoops.com/">Inside Hoops</a> -
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<a href="https://www.mlb.com/">MLB.com</a> -
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<a href="https://www.nfl.com/">NFL.com</a> -
<a href="https://www.si.com/">Sports Illustrated</a> -
<a href="http://www.headlinespot.com/subject/sports/">More >></a>
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• <b>Magazines:</b> <a href="https://www.theatlantic.com/">Atlantic</a>
<a href="https://www.bloomberg.com/businessweek">Business Week</a> -
<a href="https://www.economist.com/">Economist</a> -
<a href="https://harpers.org/">Harper's</a> -
<a href="https://www.nationalreview.com/">Nat. Review</a> -
<a href="https://www.newsweek.com/">Newsweek</a> -
<a href="https://www.newyorker.com/">New Yorker</a> -
<a href="https://people.com/">People</a> -
<a href="https://www.rd.com/">Reader's Digest</a> -
<a href="https://www.salon.com/">Salon</a> -
<a href="https://slate.com/">Slate</a> -
<a href="https://www.scientificamerican.com/">Sci. Amer.</a> -
<a href="https://time.com/">Time</a> -
<a href="https://www.tvguide.com/">TV Guide</a> -
<a href="https://www.usnews.com/">US News</a> -
<a href="http://www.headlinespot.com/type/magazines/">More >></a>
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• <b>Net/Tech News:</b> <a href="https://www.cnet.com/news/">c|net</a> -
<a href="https://www.cnn.com/business/tech">CNN Technology</a> -
<a href="https://www.clickz.com/">ClickZ</a> -
<a href="http://www.internetnews.com/">Net News</a> -
<a href="https://slashdot.org/">Slashdot</a> -
<a href="https://www.wired.com/">Wired</a> -
<a href="https://www.zdnet.com/">ZDNet</a> -
<a href="http://www.headlinespot.com/subject/technology/">More >></a>
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First Chapter: <a href="https://www.nytimes.com/books/first/first-index.html">NYT</a> -
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<a href="https://www.imdb.com/">Movie Reviews and Research</a> -
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<a href="https://www.rottentomatoes.com/top-tv/">TV Reviews</a> -
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<a href="https://blogs.herald.com/dave_barrys_blog/">Dave Barry</a> |
<a href="https://www.nytimes.com/column/david-brooks">David Brooks</a> |
<a href="https://www.thedailybeast.com/author/tina-brown.html">Tina Brown</a> |
<a href="https://www.theatlantic.com/author/ronald-brownstein/">Ron Brownstein</a> |
<a href="https://buchanan.org/blog/columns">Pat Buchanan</a> |
<a href="https://anncoulter.com/">Ann Coulter</a> |
<a href="https://www.nytimes.com/column/maureen-dowd">Maureen Dowd</a> |
<a href="https://www.washingtonpost.com/people/ej-dionne-jr/">E.J. Dionne, Jr.</a> |
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<a href="https://www.nationalreview.com/author/john-fund/">John Fund</a> |
<a href="https://www.washingtonpost.com/people/michael-gerson/">Michael Gerson</a> |
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<a href="https://www.foxnews.com/person/k/howard-kurtz.html">Howard Kurtz</a> |
<a href="https://www.marklevinshow.com/">Mark Levin</a> |
<a href="https://thenewamerican.com/contributor/michelle-malkin/">Michelle Malkin</a> |
<a href="https://www.latimes.com/people/doyle-mcmanus">Doyle McManus</a> |
<a href="https://www.thenation.com/authors/john-nichols/">John Nichols</a> |
<a href="https://www.wsj.com/news/author/peggy-noonan">Peggy Noonan</a> |
<a href="https://www.washingtonpost.com/people/kathleen-parker/">Kathleen Parker</a> |
<a href="https://townhall.com/columnists/thomassowell/">Thomas Sowell</a> |
<a href="https://www.johnstossel.com/">John Stossel</a> |
<a href="https://www.washingtonpost.com/people/george-f-will/">George Will</a> |
<a href="http://walterewilliams.com/posts/">Walter Williams</a> |
<a href="https://www.washingtonpost.com/people/fareed-zakaria">Fareed Zakaria</a>
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<a href="https://www.latimes.com/opinion">LA Times</a> |
<a href="https://www.miamiherald.com/opinion/">Miami Herald</a> |
<a href="https://www.nytimes.com/section/opinion">New York Times</a> |
<a href="https://www.sfgate.com/columns/editorials/">San Francisco Chronicle</a> |
<a href="https://www.usatoday.com/opinion/">USA Today</a> |
<a href="https://www.wsj.com/news/opinion">WSJ</a> |
<a href="https://www.washingtonpost.com/opinions/?hpid=hp__%3A&itid=hp_rhp___%3A">Washington Post</a> |
<a href="https://news.yahoo.com/">Yahoo Op/Ed</a>
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<form action="https://www.google.com/cse" id="cse-search-box-2" target="_blank">
<div>
<input type="hidden" name="cx" value="009564445132774217647:ewm5p3jwdak" />
<input type="hidden" name="ie" value="ISO-8859-1" />
<table cellspacing="0" cellpadding="0" class="gsc-search-box">
<tbody>
<tr>
<td class="gsc-input" style="padding: 0px 0px 0px 5px;">
<div class="gsc-input-box" id="bing_search_input_box">
<input type="text" size="10" class="gsc-input" name="q" title="search" id="bing_search_input_field" spellcheck="false" style="width: 100%; padding: 0px; border: none; margin: 0px; height: 1.25em; outline: none;">
</div>
</td>
<td class="gsc-search-button">
<button class="gsc-search-button gsc-search-button-v2"><svg width="13" height="13" viewBox="0 0 13 13"><title>search</title><path d="m4.8495 7.8226c0.82666 0 1.5262-0.29146 2.0985-0.87438 0.57232-0.58292 0.86378-1.2877 0.87438-2.1144 0.010599-0.82666-0.28086-1.5262-0.87438-2.0985-0.59352-0.57232-1.293-0.86378-2.0985-0.87438-0.8055-0.010599-1.5103 0.28086-2.1144 0.87438-0.60414 0.59352-0.8956 1.293-0.87438 2.0985 0.021197 0.8055 0.31266 1.5103 0.87438 2.1144 0.56172 0.60414 1.2665 0.8956 2.1144 0.87438zm4.4695 0.2115 3.681 3.6819-1.259 1.284-3.6817-3.7 0.0019784-0.69479-0.090043-0.098846c-0.87973 0.76087-1.92 1.1413-3.1207 1.1413-1.3553 0-2.5025-0.46363-3.4417-1.3909s-1.4088-2.0686-1.4088-3.4239c0-1.3553 0.4696-2.4966 1.4088-3.4239 0.9392-0.92727 2.0864-1.3969 3.4417-1.4088 1.3553-0.011889 2.4906 0.45771 3.406 1.4088 0.9154 0.95107 1.379 2.0924 1.3909 3.4239 0 1.2126-0.38043 2.2588-1.1413 3.1385l0.098834 0.090049z"></path></svg></button>
</td>
</tr>
</tbody>
</table>
</div>
</form>
</div>
</div><hr>
-->
<!-- Google CSE Search Box Ends -->
<!-- DuckDuckGo Search -->
<a href="https://duckduckgo.com/"><img src="ddg.png" HEIGHT=30 border="0" alt="DuckDuckGo" align="middle"></a>
<form method="get" action="https://duckduckgo.com/">
<table cellspacing="0" cellpadding="0" class="gsc-search-box">
<tbody>
<tr>
<td class="gsc-input" style="padding: 0px 0px 0px 5px;">
<div class="gsc-input-box" id="bing_search_input_box">
<input type="text" size="10" class="gsc-input" name="q" title="search" id="bing_search_input_field" spellcheck="false" style="width: 100%; padding: 0px; border: none; margin: 0px; height: 1.25em; outline: none;">
</div>
</td>
<td class="gsc-search-button">
<button class="gsc-search-button gsc-search-button-v2"><svg width="13" height="13" viewBox="0 0 13 13"><title>search</title><path d="m4.8495 7.8226c0.82666 0 1.5262-0.29146 2.0985-0.87438 0.57232-0.58292 0.86378-1.2877 0.87438-2.1144 0.010599-0.82666-0.28086-1.5262-0.87438-2.0985-0.59352-0.57232-1.293-0.86378-2.0985-0.87438-0.8055-0.010599-1.5103 0.28086-2.1144 0.87438-0.60414 0.59352-0.8956 1.293-0.87438 2.0985 0.021197 0.8055 0.31266 1.5103 0.87438 2.1144 0.56172 0.60414 1.2665 0.8956 2.1144 0.87438zm4.4695 0.2115 3.681 3.6819-1.259 1.284-3.6817-3.7 0.0019784-0.69479-0.090043-0.098846c-0.87973 0.76087-1.92 1.1413-3.1207 1.1413-1.3553 0-2.5025-0.46363-3.4417-1.3909s-1.4088-2.0686-1.4088-3.4239c0-1.3553 0.4696-2.4966 1.4088-3.4239 0.9392-0.92727 2.0864-1.3969 3.4417-1.4088 1.3553-0.011889 2.4906 0.45771 3.406 1.4088 0.9154 0.95107 1.379 2.0924 1.3909 3.4239 0 1.2126-0.38043 2.2588-1.1413 3.1385l0.098834 0.090049z"></path></svg></button>
</td>
</tr>
</tbody>
</table>
</form><hr>
<!-- DuckDuckGo Search 2015-->
<center>
<!-- AD_START -->
<!-- DISABLED -->
<span class="small text"><u>Advertisement:</u></span><br>
<div class="alignleft">
<script type='text/javascript'>
amzn_assoc_ad_type = 'banner';
amzn_assoc_tracking_id = 'refdeskcom';
amzn_assoc_marketplace = 'amazon';
amzn_assoc_region = 'US';
amzn_assoc_placement = 'assoc_banner_placement_default';
amzn_assoc_linkid = 'CI7V3FS5V6D3WE37';
amzn_assoc_campaigns = 'primeent';
amzn_assoc_p = '21';
amzn_assoc_banner_type = 'category';
amzn_assoc_isresponsive = 'false';
amzn_assoc_banner_id = '1R1TYHY9TYF4VF36KGG2';
amzn_assoc_width = '125';
amzn_assoc_height = '125';
</script>
<script src='//z-na.amazon-adsystem.com/widgets/q?ServiceVersion=20070822&Operation=GetScript&ID=OneJS&WS=1'></script>
</div>
<p>
<!-- AD_STOP -->
<form method="GET" action="https://www.amazon.com/exec/obidos/external-search">
<table border="1" cellpadding="3" cellspacing="0" bgcolor="ffcc00">
<tr>
<td>
<table border="0" cellpadding="3" cellspacing="0" align="top" height="80" width="170">
<tr>
<td colspan="2" bgcolor="ffcc00" height="2" valign="bottom">
<div align=center><span class="small_text"><b>Search for Books & Music:</b></span></div>
</td>
</tr>
<tr>
<td colspan="2" bgcolor="ffcc00" height="2" valign="bottom">
<div align="center"><img height="32" src="/i/amazon.png?v=2" alt="In association with amazon.com"></a><br></div>
</td>
</tr>
<tr>
<td bgcolor="ffcc00" height="0" valign="top">
<div align="center"><input type="text" name="keyword" size="18" value=""></div>
</td>
<td bgcolor="ffcc00" height="0" valign="top" align="left">
<input type="hidden" name="mode" value="blended">
<input type="hidden" name="tag" value="refdeskcom">
<input type="hidden" name="tag-id" value="refdeskcom">
<input type="hidden" name="placement" value="ap-search-go-btn.gif">
<button width="21" height="21" border="0" name="Go">Go</button>
</td>
</tr>
<tr>
<td colspan="2" bgcolor="ffcc00" height="0" align="center">
<a href="http://www.amazon.com/exec/obidos/redirect-home/refdeskcom?tag-id=refdeskcom&placement=ap-search-logo-126x32.gif&site=amazon">
<span class="small_text">As an Amazon Associate we earn from qualifying purchases</span></a>
</td>
</tr>
</table>
</td>
</tr>
</table>
</form><hr>
</center>
<span class="rd_heading">SEARCH WIKIPEDIA:</span><br>
<!-- START Wiki Search -->
<form action="https://en.wikipedia.org/wiki/Special:Search" class="bodySearch" id="bodySearchMP" name="bodySearchMP">
<table cellspacing="0" cellpadding="0" class="gsc-search-box">
<tbody>
<tr>
<td class="gsc-input" style="padding: 0px 0px 0px 5px;">
<div class="gsc-input-box" id="bing_search_input_box">
<input type="text" size="10" class="gsc-input" name="search" title="search" id="bing_search_input_field" spellcheck="false" style="width: 100%; padding: 0px; border: none; margin: 0px; height: 1.25em; outline: none;">
</div>
</td>
<td class="gsc-search-button">
<button class="gsc-search-button gsc-search-button-v2"><svg width="13" height="13" viewBox="0 0 13 13"><title>search</title><path d="m4.8495 7.8226c0.82666 0 1.5262-0.29146 2.0985-0.87438 0.57232-0.58292 0.86378-1.2877 0.87438-2.1144 0.010599-0.82666-0.28086-1.5262-0.87438-2.0985-0.59352-0.57232-1.293-0.86378-2.0985-0.87438-0.8055-0.010599-1.5103 0.28086-2.1144 0.87438-0.60414 0.59352-0.8956 1.293-0.87438 2.0985 0.021197 0.8055 0.31266 1.5103 0.87438 2.1144 0.56172 0.60414 1.2665 0.8956 2.1144 0.87438zm4.4695 0.2115 3.681 3.6819-1.259 1.284-3.6817-3.7 0.0019784-0.69479-0.090043-0.098846c-0.87973 0.76087-1.92 1.1413-3.1207 1.1413-1.3553 0-2.5025-0.46363-3.4417-1.3909s-1.4088-2.0686-1.4088-3.4239c0-1.3553 0.4696-2.4966 1.4088-3.4239 0.9392-0.92727 2.0864-1.3969 3.4417-1.4088 1.3553-0.011889 2.4906 0.45771 3.406 1.4088 0.9154 0.95107 1.379 2.0924 1.3909 3.4239 0 1.2126-0.38043 2.2588-1.1413 3.1385l0.098834 0.090049z"></path></svg></button>
</td>
</tr>
</tbody>
</table>
</form>
<span class="small_text">
<a href="https://en.wikipedia.org/wiki/Special:Random">Random Wikipedia Article</a>
</span>
<!-- END Wiki Search -->
<hr>
<form name="f" method="GET" action="https://news.google.com/news">
<span class="rd_heading">SEARCH GOOGLE NEWS:</span><br>
<span class="small_text"> (e.g., Terror)</span><br>
<input TYPE=hidden name=hl value=en>
<input type="hidden" name="edition" value="us">
<input TYPE=hidden name=ie value="ascii">
<table cellspacing="0" cellpadding="0" class="gsc-search-box">
<tbody>
<tr>
<td class="gsc-input" style="padding: 0px 0px 0px 5px;">
<div class="gsc-input-box" id="bing_search_input_box">
<input type="text" size="10" class="gsc-input" name="q" title="search" id="bing_search_input_field" spellcheck="false" style="width: 100%; padding: 0px; border: none; margin: 0px; height: 1.25em; outline: none;">
</div>
</td>
<td class="gsc-search-button">
<button class="gsc-search-button gsc-search-button-v2"><svg width="13" height="13" viewBox="0 0 13 13"><title>search</title><path d="m4.8495 7.8226c0.82666 0 1.5262-0.29146 2.0985-0.87438 0.57232-0.58292 0.86378-1.2877 0.87438-2.1144 0.010599-0.82666-0.28086-1.5262-0.87438-2.0985-0.59352-0.57232-1.293-0.86378-2.0985-0.87438-0.8055-0.010599-1.5103 0.28086-2.1144 0.87438-0.60414 0.59352-0.8956 1.293-0.87438 2.0985 0.021197 0.8055 0.31266 1.5103 0.87438 2.1144 0.56172 0.60414 1.2665 0.8956 2.1144 0.87438zm4.4695 0.2115 3.681 3.6819-1.259 1.284-3.6817-3.7 0.0019784-0.69479-0.090043-0.098846c-0.87973 0.76087-1.92 1.1413-3.1207 1.1413-1.3553 0-2.5025-0.46363-3.4417-1.3909s-1.4088-2.0686-1.4088-3.4239c0-1.3553 0.4696-2.4966 1.4088-3.4239 0.9392-0.92727 2.0864-1.3969 3.4417-1.4088 1.3553-0.011889 2.4906 0.45771 3.406 1.4088 0.9154 0.95107 1.379 2.0924 1.3909 3.4239 0 1.2126-0.38043 2.2588-1.1413 3.1385l0.098834 0.090049z"></path></svg></button>
</td>
</tr>
</tbody>
</table>
</form>
<hr>
<form method="GET" action="https://finance.yahoo.com/q">
<span class="rd_heading">GET STOCK QUOTES:</span><br>
<span class="small_text">Enter Stock Symbol / <a href="https://finance.yahoo.com/">Symbol Lookup</a></span><br>
<table cellspacing="0" cellpadding="0" class="gsc-search-box">
<tbody>
<tr>
<td class="gsc-input" style="padding: 0px 0px 0px 5px;">
<div class="gsc-input-box" id="bing_search_input_box">
<input type="text" size="10" class="gsc-input" name="s" title="search" id="bing_search_input_field" spellcheck="false" style="width: 100%; padding: 0px; border: none; margin: 0px; height: 1.25em; outline: none;">
</div>
</td>
<td class="gsc-search-button">
<button class="gsc-search-button gsc-search-button-v2"><svg width="13" height="13" viewBox="0 0 13 13"><title>search</title><path d="m4.8495 7.8226c0.82666 0 1.5262-0.29146 2.0985-0.87438 0.57232-0.58292 0.86378-1.2877 0.87438-2.1144 0.010599-0.82666-0.28086-1.5262-0.87438-2.0985-0.59352-0.57232-1.293-0.86378-2.0985-0.87438-0.8055-0.010599-1.5103 0.28086-2.1144 0.87438-0.60414 0.59352-0.8956 1.293-0.87438 2.0985 0.021197 0.8055 0.31266 1.5103 0.87438 2.1144 0.56172 0.60414 1.2665 0.8956 2.1144 0.87438zm4.4695 0.2115 3.681 3.6819-1.259 1.284-3.6817-3.7 0.0019784-0.69479-0.090043-0.098846c-0.87973 0.76087-1.92 1.1413-3.1207 1.1413-1.3553 0-2.5025-0.46363-3.4417-1.3909s-1.4088-2.0686-1.4088-3.4239c0-1.3553 0.4696-2.4966 1.4088-3.4239 0.9392-0.92727 2.0864-1.3969 3.4417-1.4088 1.3553-0.011889 2.4906 0.45771 3.406 1.4088 0.9154 0.95107 1.379 2.0924 1.3909 3.4239 0 1.2126-0.38043 2.2588-1.1413 3.1385l0.098834 0.090049z"></path></svg></button>
</td>
</tr>
</tbody>
</table>
</form>
<span class="small_text">
<a href="https://finance.yahoo.com/q?s=%5EDJI">Dow Jones</a> |
<a href="https://finance.yahoo.com/q?s=%5EIXIC">NASDAQ</a> |
<a href="https://finance.yahoo.com/q?s=%5EGSPC">S&P</a> |
<a href="https://finance.yahoo.com/">Yahoo Finance</a>
</span>
</div>
</div><!-- search_resources end -->
<span id="social_networks_wrapper" class="no_mobile">
<div id="social_networks">
<span class="rd_heading">SOCIAL NETWORKS:</span><br>
<a href="https://www.facebook.com/">Facebook</a> |
<a href="https://twitter.com/">Twitter</a> |
<a href="https://www.linkedin.com">LinkedIn</a> |
<a href="https://www.pinterest.com">Pinterest</a> |
<a href="https://instagram.com">Instagram</a> |
<a href="http://www.ebizmba.com/articles/social-bookmarking-websites">More >></a>
</div>
</span>
<div id="dictionary">
<span class="rd_heading">DICTIONARY:</span><span class="small_text"><br><br></span>
<!-- Merriam-Webster Searchbox Style 4 -->
<script language="Javascript">
function getValue(term){
if(document.query.elements[0].checked == true){document.location.href = "http://www.merriam-webster.com/dictionary/" + term;}
else if(document.query.elements[1].checked == true){document.location.href = "https://www.merriam-webster.com/thesaurus/" + term;}}
</script>
<form name="query" method="get" action="javascript:getValue(document.query.va.value)">
<div style="margin:0;padding:0;border:solid 1px #000000;width:170px;text-align:center;font-family:Geneva,Arial,Helvetica,sans-serif;font-size:12px;font-weight:bold;">
<div style="margin:0;padding:0;background-color:#000062;color:#FFFFFF;">
Merriam-Webster Online
</div>
<div align="center" style="margin:0;padding:3px;background-color:#E4EBFD;">
<table align="center" cellpadding="0" cellspacing="0" style="margin:0;padding:0;font-family:Geneva,Arial,Helvetica,sans-serif;font-size:12px;font-weight:bold;color:#000066;">
<tr>
<td width="55px" style="margin:0;padding:0;">
<img src="https://merriam-webster.com/assets/mw/static/app-css-images/logos/MW_logo.png" width="44" height="44" hspace="0" vspace="0" align="left" />
</td>
<td align="left" style="margin:0;padding:0;vertical-align:middle;">
<input type="radio" name="mySelect" value="Dictionary" checked> Dictionary<br />
<input type="radio" name="mySelect" value="Thesaurus"> Thesaurus
</td>
</tr>
</table>
</div>
<div style="margin:0;padding:3px;background-color:#E4EBFD;">
<input type="text" align="top" name="va" size="19" />
<input type="submit" alt="Go" name="Lookup" value="Lookup">
</div>
</div>
</form>
</center>
<hr>
<!--dictionary lookup box by TheFreeDictionary.com-->
<a href="https://www.thefreedictionary.com" title="ThefreeDictionary.com">TheFreeDictionary</a>:<br>
<form method="GET" action="https://www.thefreedictionary.com/_/partner.aspx" style="display:inline;" onsubmit="return this.Word.value>''">
<input type="hidden" name="pid" value="aff23">
<input type="text" name="Word" size="22" maxlength="70"><br>
<span class="small_text">
<input type="radio" name="Set" value="" checked>Dictionary/Thesaurus<br>
<input type="radio" name="Set" value="computing-dictionary">Computing Dictionary<br>
<input type="radio" name="Set" value="medical-dictionary">Medical Dictionary<br>
<input type="radio" name="Set" value="legal-dictionary">Legal Dictionary<br>
<input type="radio" name="Set" value="financial-dictionary">Financial Dictionary<br>
<input type="radio" name="Set" value="acronyms">Acronyms<br>
<input type="radio" name="Set" value="encyclopedia">Wikipedia Encyclopedia<br>
<input type="radio" name="Set" value="columbia">Columbia Encyclopedia<br>
</span>
<input type="submit" value="Search">
</form>
<!--end of dictionary lookup box--><br>
<span id="white_pages" class="no_mobile">
<hr>
<span class="rd_heading">PEOPLE WHITE PAGES RESOURCES:</span><p>
<ul>
<li><a href="https://www.50states.com/whitepages/">50States.com</a></li>
<li><a href="https://www.anywho.com/whitepages">AnyWho.com</a></li>
<li><a href="https://www.intelius.com/">Intelius.com</a></li>
<li><a href="https://www.usphonebook.com/">Reverse Phone Lookup</a></li>
<li><a href="https://www.addresses.com/reverse-address">Reverse Address Lookup</a></li>
<li><a href="https://www.whitepages.com/person">WhitePages.com</a></li>
<li><a href="http://search.yahoo.com/web?fr=people">Yahoo.com</a></li>
</ul>
</span>
<span id="yellow_pages" class="no_mobile">
<hr>
<span class="rd_heading">BUSINESS YELLOW PAGES RESOURCES:</span><p>
<ul>
<li><a href="https://www.50states.com/yellowpages/">50States.com</a></li>
<li><a href="https://www.anywho.com/yellow-pages">AnyWho.com</a></li>
<li><a href="https://www.whitepages.com/business">WhitePages.com</a></li>
<li><a href="https://www.yellowbook.com/">YellowBook.com</a></li>
<li><a href="https://www.yellowpages.com/">YellowPages.com</a></li>
<li><a href="https://local.yahoo.com">Yahoo.com</a></li>
</ul>
</span>
</div>
<section id=driving_directions_wrapper" class="no_mobile">
<div id="driving_directions">
<span class="rd_heading">DRIVING DIRECTIONS:</span><br>
<a href="https://www.mapquest.com/">MapQuest.com</a>: <a href="https://help.mapquest.com/">Help</a>
<!-- START_ MapQuest Search -->
<form action="https://www.mapquest.com/directions" method="get">
<div align="left">
<input type="hidden" name="go" value="1"><br>
<table border="0" cellpadding="0" cellspacing="0" style="font: 11px Arial,Helvetica;">
<tr>
<td colspan="2" style="font-weight: bold;">FROM:</td>
</tr>
<tr>
<td colspan="2">Address or Intersection:</td>
</tr>
<tr>
<td colspan="2">
<input type="text" name="1a" size="22" maxlength="30" value="">
</td>
</tr>
<tr>
<td colspan="2">City:</td>
</tr>
<tr>
<td colspan="2">
<input type="text" name="1c" size="22" maxlength="30" value="">
</td>
</tr>
<tr>
<td>State/Province:</td>
<td>ZIP Code:</td>
</tr>
<tr>
<td>
<input type="text" name="1s" size="4" maxlength="2" value="">
</td>
<td>
<input type="text" name="1z" size="8" maxlength="10" value="">
</td>
</tr>
<tr>
<td>Country:</td>
</tr>
<tr>
<td>
<select name="1y">
<option value="CA">Canada</option>
<option value="US" selected>United States</option>
</select>
</td>
</tr>
<tr>
<td colspan="2" style="font-weight: bold;"> </td>
</tr>
<tr>
<td colspan="2" style="font-weight: bold;">TO:</td>
</tr>
<tr>
<td colspan="2">Address or Intersection:</td>
</tr>
<tr>
<td colspan="2"><input type="text" name="2a" size="22" maxlength="30" value=""></td>
</tr>
<tr>
<td colspan="2">City:</td>
</tr>
<tr>
<td colspan="2">
<input type="text" name="2c" size="22" maxlength="30" value="">
</td>
</tr>
<tr>
<td>State/Province:</td>
<td>ZIP Code:</td>
</tr>
<tr>
<td><input type="text" name="2s" size="4" maxlength="2" value=""></td>
<td><input type="text" name="2z" size="8" maxlength="10" value=""></td>
</tr>
<tr>
<td>Country:</td>
</tr>
<tr>
<td>
<select name="2y">
<option value="CA">Canada</option>
<option value="US" selected>United States</option>
</select>
</td>
</tr>
<tr>
<td colspan="2" style="text-align: left; padding-top: 10px;">
<input type="submit" name="dir" value="Get Directions">
<input type="hidden" name="CID" value="lfddwid">
</td>
</tr>
</table>
<hr>
<ul>
<li><a href="https://www.mapmyride.com/">MapMyRide Cycling Maps</a></li>
<li><a href="https://www.nationalgeographic.com/maps/">Maps: USA & World</a></li>
<li><a href="https://maps.google.com/">Google Maps</a></li>
<li><a href="https://wego.here.com/">HERE WeGo</a></li>
<ul>
</div>
</form>
<!-- END_ MapQuest Search --><p>
</div>
<div id="misc_resources">
<span class="rd_heading">MISC. RESOURCES:</span><p>
<ul>
<li><a href="https://9-11commission.gov/report/">9/11 Commission Full Report</a></li>
<li><a href="attack.html">America Responds</a></li>
<li><a href="https://www.defense.gov/Newsroom/releases/">DoD News Releases</a></li>
<li><a href="https://www.fbi.gov/news/pressrel">FBI News Releases</a></li>
<li><a href="mideastnews.html">Middle East News Resources</a></li>
<li><a href="https://news.un.org/en/">UN News Service</a></li>
</ul>
</div>
</section>
<section id="rd_left_lower" class="no_mobile"><!-- intentionally nested within rd_left -->
<div id="facts_at_a_glance">
<div class="title_div"><span class="title_span">Facts-at-a-Glance</span></div>
<div id="facts_at_a_glance_items">
<ul>
<li><a href="http://www.ourdocuments.gov/content.php?page=milestone">100 Milestone Documents</a></li>
<li><a href="https://www.voipreview.org/">10-10 Phone Rates: Comps</a></li>
<li><a href="https://www.census.gov/">U.S. Census Statistics</a></li>
<li>College Rankings: <a href="https://www.usnews.com/best-colleges/rankings/national-universities">1</a> |
<a href="http://www.forbes.com/top-colleges/list/">2</a> |
<a href="http://www.payscale.com/best-colleges">3</a></li>
<li><a href="https://www.50states.com/">50States.com</a></li>
<li><a href="https://constitutioncenter.org/interactive-constitution">U.S. Constitution</a></li>
</ul>
<hr>
<ul>
<li><a href="https://www.800-numbers.net/">800-numbers.net</a></li>
<li><a href="https://abtolls.com/">A Bell Tolls: LD Rate Comps</a></li>
<li><a href="https://www.acronymfinder.com">Acronym Finder</a></li>
<li><a href="https://www.ssa.gov/oact/STATS/table4c6.html">Actuarial Life Table</a></li>
<li><a href="https://www.dhl.com/us-en/home.html">DHL</a></li>
<li>Airline Flight Tracker: <a href="https://flightaware.com/">1</a> |
<a href="https://www.flightview.com/TravelTools/">2</a> |
<a href="http://www.flightstats.com/go/FlightTracker/flightTracker.do">3</a> |
<a href="https://flightwise.com/">4</a></li>
<li><a href="http://www.tollfreeairline.com/">Airline Toll-Free Numbers</a></li>
<li><a href="/airport_codes.html">Airport Code Lookup</a></li>
<li><a href="https://www.dhs.gov/how-do-i/check-wait-times">Airport Security Wait Times</a></li>
<li><a href="https://data.census.gov/cedsci/">American Fact Finder</a></li>
<li><a href="https://www.annualcreditreport.com/cra/index.jsp">Annual Credit Report (Free)</a></li>
<li><a href="http://www.fonefinder.net/">Area Code Finder</a></li>
<li><a href="https://www.bennetyee.org/ucsd-pages/area.html">Area Code Listing </a></li>
<li><a href="https://www.allareacodes.com/area-code-map.htm">Area Code Map</a></li>
<li><a href="https://www.areavibes.com/">AreaVibes: City Data</a></li>
<li><a href="https://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmi-m.htm">BMI Calculator</a></li>
<li><a href="http://www.drbo.org/">Bible: Douay-Rheims Cath. Ver.</a></li>
<li><a href="https://www.mechon-mamre.org/e/et/et0.htm">Bible: Hebrew Ver.</a></li>
<li><a href="https://www.bartleby.com/108/">Bible: King James Ver.</a></li>
<li><a href="https://www.biography.com/">Biography.com</a></li>
<li><a href="http://www.searchforancestors.com/utility/dayofweek.html">Calculator: Day of the Week</a></li>
<li><a href="topcalc.html">Calculators</a></li>
<li><a href="https://calendarhome.com/print-a-calendar/">Calendar: 10,000 Year</a></li>
<li><a href="https://www.timeanddate.com/calendar/custommenu.html">Calendar: Customized</a></li>
<li><a href="https://www.timeanddate.com/date/duration.html">Calendar: Days Between Dates</a></li>
<li><a href="http://www.earthcalendar.net/index.php">Calendar: Earth</a></li>
<li><a href="https://www.infoplease.com/calendar">Calendar: Perpetual</a></li>
<li><a href="https://www.canadapost.ca/cpo/mc/languageswitcher.jsf">Canada Postal Lookup</a></li>
<li><a href="http://www.chemicalelements.com">Chemical Elements.com</a></li>
<li><a href="https://www.cia.gov/the-world-factbook/field/political-parties-and-leaders/">Chiefs of State</a></li>
<li><a href="https://www.cia.gov/the-world-factbook/">CIA World Fact Book</a></li>
<li><a href="http://www.city-data.com/">City Data (USA)</a></li>
<li><a href="https://www.consumerworld.org/">Consumer Info</a></li>
<li><a href="https://www.bls.gov/cpi/">Consumer Price Index</a></li>
<li><a href="https://www.usa.gov/Contact/Elected.shtml">Contacting Congress</a></li>
<li><a href="https://www.onlineconversion.com/">Convert Anything</a></li>
<li><a href="https://en.wikipedia.org/wiki/List_of_country_calling_codes">Country Calling Codes</a></li>
<li><a href="/coupons.html">Coupons for Online Shopping</a></li>
<ul>
</div>
<hr>
<div id="dictionaries">
<span class="rd_heading">DICTIONARIES:</span><br>
<ul>
<li><a href="https://www.ahdictionary.com/">American Heritage</a></li>
<li><a href="https://www.macmillandictionary.com/us/thesaurus-category/american/general-words-relating-to-banking">Banking</a></li>
<li><a href="https://www.lexico.com">Compact OED</a></li>
<li><a href="https://www.webopedia.com/">Computing</a></li>
<li><a href="https://www.crossword-dictionary.com/">Crossword</a></li>
<li><a href="https://financial-dictionary.thefreedictionary.com">Financial</a></li>
<li><a href="https://www.computeruser.com/dictionary/">High-Tech</a></li>
<li><a href="https://www.nolo.com/dictionary">Legal</a></li>
<li><a href="https://www.medicinenet.com/script/main/hp.asp">Medical</a></li>
<li><a href="https://www.onelook.com/reverse-dictionary.shtml">Reverse Dictionary</a></li>
<li><a href="https://www.spanishdict.com/">Spanish-English</a></li>
<li><a href="https://howjsay.com/">Talking Dictionary</a></li>
<li><a href="http://visual.merriam-webster.com/">Visual Dictionary</a></li>
<li><a href="https://w1.weather.gov/glossary/">Weather Glossary</a></li>
<li><a href="factdict.html">More >></a>
</ul>
</div>
<hr>
<div id="health_and_medicine">
<span class="rd_heading">HEALTH & MEDICINE:</span><br>
<ul>
<li><a href="covid19.html">COVID-19 Coronavirus Resources</a></li>
<li><a href="https://www.certificationmatters.org/">Doctor Board Verification</a></li>
<li><a href="https://medlineplus.gov/druginformation.html">Drug Information</a></li>
<li><a href="https://medlineplus.gov/">Health Information</a></li>
<li><a href="https://health.usnews.com/best-hospitals/rankings">Hospital Rankings</a></li>
<li><a href="https://www.bartleby.com/107/">Gray's Anatomy</a></li>
</ul>
</div>
<hr>
<div id="encyclopedias">
<span class="rd_heading">ENCYCLOPEDIAS:</span><br>
<ul>
<li><a href="http://en.wikipedia.org/wiki/Encyclopædia_Britannica_Eleventh_Edition">1911 Encyclopedia Britannica</a></li>
<li><a href="https://www.britannica.com/">Britannica Online</a></li>
<li><a href="https://www.thecanadianencyclopedia.ca/en">Canadian</a></li>
<li><a href="https://www.encyclopedia.com/">Encyclopedia.com</a></li>
<li><a href="https://eol.org/">Encyclopedia of Life</a></li>
<li><a href="https://www.nolo.com/legal-encyclopedia">Legal</a></li>
<li><a href="https://medlineplus.gov/encyclopedia.html">Medical</a></li>
<li><a href="https://w1.weather.gov/glossary/">Weather</a></li>
<li><a href="https://en.wikipedia.org/wiki/Main_Page">Wikipedia</a></li>
<li><a href="factency.html">More >></a></li>
</ul>
</div>
<hr>
<div id="find">
<span class="rd_heading">FIND:</span><br>
<ul>
<li><a href="https://www.ancestry.com/">Ancestors</a></li>
<li>Apartments: <a href="https://www.apartmentguide.com/">1</a> | <a href="https://www.doorsteps.com/">2</a> | <a href="https://www.rent.com/">3</a></li>
<li><a href="https://www.petersons.com/">College</a></li>
<li><a href="https://doctor.webmd.com/">Doctor</a></li>
<li><a href="https://www.usa.gov/Contact/Elected.shtml">Elected Officials</a></li>
<li><a href="https://www.factcheck.org/">Fact Check.org</a></li>
<li><a href="http://www.mayoclinic.org/health/FirstAidIndex/FirstAidIndex">First-Aid Guide</a></li>
<li><a href="https://www.realtor.com/">House</a> | <a href="https://www.zillow.com/">House Value</a></li>
<li><a href="https://www.lawyers.com/">Lawyer</a></li>
<li><a href="https://medlineplus.gov/">Health Information</a></li>
<li><a href="https://lp.findlaw.com/">Legal Information</a></li>
<li><a href="https://medlineplus.gov/">Medical Information</a></li>
<li><a href="https://refdesk.whitepages.com/">People</a></li>
<li><a href="https://virtualchase.justia.com/wiki/people-finders/">People Finder Guide</a></li>
</ul>
<hr>
<ul>
<li><a href="https://www.cia.gov/the-world-factbook/references/flags-of-the-world/">Flags of the World</a></li>
<li><a href="https://www.infoplease.com/homework-help/writing-grammar/foreign-words-and-phrases1">Foreign Words and Phrases</a></li>
<li><a href="https://gethuman.com/">Get Human Customer Service</a></li>
<li><a href="https://www.freemaptools.com/how-far-is-it-between.htm">How Far Is It?</a></li>
<li><a href="https://www.kbb.com/">Kelley Blue Book</a></li>
<li>Language Translator: <a href="https://translate.google.com">1</a> | <a href="https://www.freetranslations.org/">2</a></li>
<li><a href="https://www.findlaw.com/">Legal Resources</a></li>
<li><a href="https://www.loc.gov/">Library of Congress</a></li>
<li><a href="https://www.payphone-project.com/usps-mailboxes/index.html">Mailbox (USPS) Locator</a></li>
<li><a href="https://consumermedsafety.org/">MedSafety Info</a></li>
<li><a href="https://www.merckmanuals.com/home">Merck Manual Home Edition</a></li>
<li><a href="https://www.zillow.com/mortgage-calculator/">Mortgage Loan Calculator</a></li>
</ul>
<hr>
<ul>
<li><a href="https://www.loc.gov/rr/news/oltitles.html">Newspaper Archives</a></li>
<li><a href="https://www.bls.gov/ooh/">Occupational Handbook</a></li>
<li><a href="https://www.onlineconversion.com/">Online Unit Conversion</a></li>
<li><a href="http://www.pdrhealth.com/home/home.aspx">Physician's Desk Ref: Drugs</a></li>
<li><a href="https://postcalc.usps.com/">Postage Price Calculator</a></li>
<li><a href="https://www.census.gov/popclock/">Population Clocks: US/World</a></li>
<li><a href="https://publicrecords.onlinesearches.com/">Public Records Database</a></li>
<li><a href="https://www.bartleby.com/176/">Robert's Rules of Order</a></li>
<li><a href="https://rulers.org/">Rulers of the World</a></li>
<li><a href="https://www.kff.org/statedata/">State Health Facts</a></li>
<li><a href="https://www.bartleby.com/141/">Strunk's Elements of Style</a></li>
<li><a href="https://www.ups.com/us/en/global.page">UPS</a></li>
<li><a href="https://www.census.gov/">U.S. Census Bureau</a></li>
<li><a href="https://www.usps.com/">U.S. Postal Service</a></li>
<li><a href="http://www.wa-wd.com/">Who's Alive/Who's Dead</a></li>
<li><a href="https://www.worldatlas.com/aatlas/world.htm">World Atlas/Geo. Facts</a></li>
<li><a href="https://www.worldtimeserver.com/">World Time Server</a></li>
<li><a href="https://www.timeanddate.com/time/map/">World Time Zone Map</a></li>
<li><a href="https://www.yellowpages.com/">Yellow Pages</a></li>
<li><a href="https://tools.usps.com/go/ZipLookupAction">ZIP 4 Code Look-up</a></li>
<li><a href="https://worldpostalcode.com/">ZIP Codes: International</a></li>
<li><a href="instant.html">More >></a></li>
</ul>
</div>
</div><!-- end of Facts-at-a-Glance -->
<div id="site_information">
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[CNN](https://www.cnn.com/) |
[CTV](https://www.ctvnews.ca/) |
[Daily Beast](https://www.thedailybeast.com/) |
[Drudge Report](https://www.drudgereport.com/) |
[Excite](https://www.excite.com/news) |
[Forbes](https://www.forbes.com/) |
[FOX](https://www.foxnews.com/) |
[Google](https://news.google.com/) |
[Guardian](https://www.theguardian.com/us) |
[Huffington Post](https://www.huffpost.com/) |
[LA Times](https://www.latimes.com/) |
[MSN](https://www.msn.com/en-us/) |
[MSNBC](https://www.msnbc.com/) |
[Middle East News](mideastnews.html) |
[NBC](https://www.nbcnews.com/) |
[NPR](https://www.npr.org/sections/news) |
[New York Daily News](https://www.nydailynews.com/) |
[New York Times](https://www.nytimes.com/) |
[News Clusters](https://www.newsclusters.com) |
[NewsNow](https://www.newsnow.co.uk/h/) |
[Newsweek](https://www.newsweek.com/) |
[OANN](https://www.oann.com/) |
[PBS NewsHour](https://www.pbs.org/newshour/) |
[Reuters](https://www.reuters.com/) |
[San Francisco Chronicle](https://www.sfchronicle.com/) |
[Sky News](https://news.sky.com/) |
[Time](https://time.com/) |
[Today](https://www.today.com/) |
[UPI](https://www.upi.com/) |
[USA Today](https://www.usatoday.com/) |
[WN.com](https://wn.com/) |
[Wall Street Journal](https://www.wsj.com/) |
[Wash. Times](https://www.washingtontimes.com/) |
[Wash. Post](https://www.washingtonpost.com/) |
[Wopular](http://www.wopular.com/home/full_news_rack) |
[WorldProNews](http://www.worldpronews.com/) |
[Yahoo](https://news.yahoo.com/)
CURRENT GAS & OIL PRICES:
[AAA: Gas Prices](https://gasprices.aaa.com/) |
[AAA: Fuel Cost Calculator](https://gasprices.aaa.com/) |
[DOE: Energy Historical Data](https://www.eia.gov/state/) |
[DOE: Gasoline/Diesel Fuel Update](https://www.eia.gov/petroleum/gasdiesel/) |
[DOE: Sources of Crude Oil](https://www.eia.gov/dnav/pet/pet_move_impcus_a2_nus_ep00_im0_mbbl_m.htm) |
[DOE: This Week In Petroleum](https://www.eia.gov/petroleum/weekly/) |
[GasBuddy: Gas Prices by Zip Code](https://www.gasbuddy.com/) |
[How Gas Prices Work](https://auto.howstuffworks.com/fuel-efficiency/fuel-consumption/gas-price.htm) |
[Mapquest Gas Prices](https://www.mapquest.com/search/results?query=Gas) |
[Oil Price.com](https://oilprice.com/) |
[USA Gas Prices Map](https://www.gasbuddy.com/gaspricemap)
GOVERNMENT & ECONOMY:
* [Contact USA Elected Officials](https://www.usa.gov/Contact/Elected.shtml)
* [Currency Exchange Rates](https://www.xe.com/)
* [Government Stats](https://www.data.gov/)
* [Job Search Resources](jobsearch.html)
* [Military Information](https://www.defense.gov/)
* [USA Gas Price Map](https://www.gasbuddy.com/gaspricemap)
* [U.S. Cities Guide](http://www.city-data.com/)
* [U.S. Debt Clock: Real Time](https://www.usdebtclock.org/)
* [U.S. Debt & Historical Data](https://www.treasurydirect.gov/govt/reports/pd/histdebt/histdebt.htm)
* [U.S. FISC Public Filings](https://www.fisc.uscourts.gov/public-filings)
* [U.S. Gov't Sites](https://www.usa.gov/)
* [U.S. Representatives](https://www.house.gov/representatives)
* [U.S. Senators](https://www.senate.gov/senators/states.htm)
* [Failed Banks](https://www.fdic.gov/bank/individual/failed/banklist.html)
* [U.S. / World Pop Clock](https://www.census.gov/popclock/)
* [Vital Records](https://www.vitalrec.com/)
FEATURES:
* [Current Dow Jones Avg.](https://finance.yahoo.com/q?s=%5edji&d=t)
* [Crude Oil | Energy Prices](https://www.bloomberg.com/energy)
* [Commodities Futures](https://money.cnn.com/data/commodities/)
* [Daily Fuel Gauge Report](https://gasprices.aaa.com/)
* [Dear Abby](https://www.uexpress.com/dearabby)
* [Drudge Report](https://www.drudgereport.com/)
* [Market Update and Charts](https://finance.yahoo.com/topic/stock-market-news)
* Comics [1](https://www.washingtonpost.com/entertainment/comics/) |
[2](https://www.gocomics.com/?ref=comics) |
[Sports](https://sports.yahoo.com/)
* [Health](https://news.google.com/news/section?cf=all&pz=1&topic=m&siidp=94b96873970b99267fa5df53b7ae8722a3ea&ict=ln) |
[Tech](https://news.google.com/topics/CAAqJggKIiBDQkFTRWdvSUwyMHZNRGRqTVhZU0FtVnVHZ0pWVXlnQVAB) |
[Science](https://news.google.com/topics/CAAqJggKIiBDQkFTRWdvSUwyMHZNRFp0Y1RjU0FtVnVHZ0pWVXlnQVAB)
* [Finance](https://finance.yahoo.com) |
[Politics](https://www.yahoo.com/politics) |
[Popular](https://news.yahoo.com/)
* [Entertainment](https://ew.com/)
* Obituaries [1](https://www.legacy.com/) |
[2](http://www.obituaries.com/ns/obituariescom/obits.aspx) |
[3](https://www.obitlinkspage.com/)
* [Weather](https://www.weather.gov/)
Help and Advice
**Browser Updates:**
* [Apple Safari](https://www.apple.com/safari/)
* [Google Chrome](https://www.google.com/chrome/downloads/)
* [Internet Explorer](http://windows.microsoft.com/en-us/internet-explorer/download-ie)
* [Opera](https://www.opera.com/download)
---
* [Ask the Experts](expert.html)
* [Consumer Search](https://www.consumersearch.com/)
* [Do-it-Yourself.com](https://www.doityourself.com/)
* [Do-it-Yourself Resources](doitself.html)
* [FindHow](https://findhow.com/)
* [Free Legal Advice](https://www.freeadvice.com/)
* [Homework Helper](homework.html)
* [How Stuff Works](https://www.howstuffworks.com/)
* [How To Clean Anything](https://www.ehow.com/how_2049722_clean-anything.html)
* [Information Please](https://www.infoplease.com/)
* [Microsoft Support](https://support.microsoft.com/)
* [Mozilla Firefox](http://www.mozilla.com/)
Top Reference Tools
* **Almanacs*** * [Refdesk's Daily Almanac](quote.html)
* [The Old Farmer's Almanac](https://www.almanac.com/)
* **Biographies**
* [Biography.com](https://www.biography.com/)
* [Who2](https://www.who2.com/)
* [More >>](/factbiog.html)
* **Calculators & Conversion**
* [Calculators and Conversions](topcalc.html)
* [Currency Converter](https://www.oanda.com/currency/converter/)
* **Census & Demographics**
* [American Factfinder](https://data.census.gov/cedsci/)
* [Country Statistics](https://www.infoplease.com/world/economic-statistics/country-statistics-glance)
* [Home Area](https://www.homearea.com/)
* [NationMaster](https://www.nationmaster.com/)
* [StateMaster](http://www.statemaster.com)
* [Worldwide Census Info](https://www.census.gov/programs-surveys/international-programs/about/idb.html)
* **Date and Time**
* [Days Between Dates](https://www.daysbetweendates.net/)
* [Perpetual Calendar](https://www.infoplease.com/calendar)
* [Timeanddate.com](https://www.timeanddate.com/)
* **Dictionary & Thesaurus**
* [Merriam-Webster Online](https://www.merriam-webster.com/)
* [TheFreeDictionary](https://www.thefreedictionary.com)
* [TheFreeThesaurus](https://www.freethesaurus.com)
* [Thesaurus.com](https://www.thesaurus.com/)
* [YourDictionary](https://www.yourdictionary.com/)
* [Vocabulary.com](https://www.vocabulary.com)
* [More >>](factdict.html)
* **Encyclopedias**
* [Columbia Encyclopedia](https://encyclopedia2.thefreedictionary.com/)
* [Encyclopedia Britannica](https://www.britannica.com/)
* [Encyclopedia.com](https://www.encyclopedia.com/)
* [More >>](factency.html)
* **Genealogy/Obituaries**
* [Ellis Island Records](https://www.libertyellisfoundation.org/)
* [Cyndi's Genealogy Sites](https://www.cyndislist.com/)
* [Family Search](http://www.familysearch.org/)
* [Obituary Notices](https://www.legacy.com/)
* [Obits 101](https://www.big101.com/OBITUARIES101.htm)
* [Researching Your Roots](http://www.genealogyspot.com/features/gettingstarted.htm)
* [More >>](factgene.html)
* **Geography & Maps**
* [Aerial/Satellite Images](http://www.terrafly.com/)
* [Google Maps](https://maps.google.com/)
* [MapMyRide](https://www.mapmyride.com/)
* [MapQuest](https://www.mapquest.com/)
* [National Geographic](https://www.nationalgeographic.com/maps/)
* [Topo Maps](https://www.anyplaceamerica.com)
* **Health**
* [Centers For Disease Control](https://www.cdc.gov/)
* [Mayo Clinic](https://www.mayoclinic.org/)
* [MEDLINE Plus](https://medlineplus.gov/)
* [National Cancer Center](https://www.cancer.gov/)
* [Nat. Inst. of Health](https://www.nih.gov/health-information)
* [Symptom Checker](https://symptoms.webmd.com/default.htm)
* [WebMD](https://www.webmd.com/)
* **People Finder**
* [WhitePages.com](https://www.whitepages.com/)
* **Quotations**
* [Bartlett's](https://www.bartleby.com/quotations/)
* [Quoteland.com](http://www.quoteland.com/)
* **Style & Writing Guides**
* [APA Style](https://apastyle.apa.org/apa-style-help)
* [Citation Generation Tool](https://www.citationgenerator.com/)
* [Citing Your Sources](https://www.lib.berkeley.edu/research-support/cite-sources)
* [Common Errors in English](https://brians.wsu.edu/common-errors/)
* [Elements of Style](https://www.bartleby.com/141/index.html)
* [Grammarly](https://www.grammarly.com)
* [OWL Online Writing Lab](https://owl.purdue.edu/owl/purdue_owl.html)
* [Resources for Writers](http://jacklynch.net/Writing/links.html)
* [Ultimate Guide to Writing Styles](https://online.maryville.edu/online-bachelors-degrees/liberal-studies/ultimate-guide-to-writing-styles/)
Just For Fun
* [AddictingGames.com](https://www.addictinggames.com/)
* [Agame.com](https://www.agame.com/)
* [Anagram Server](https://www.wordsmith.org/anagram/)
* [Analogy of the Day](https://www.infoplease.com/analogies)
* [Aphorisms Galore!](https://www.aphorismsgalore.com/)
* [Brain Games](https://www.proprofsgames.com/)
* [Chess Games](https://www.chess.com/)
* [Classical Music Archives](https://www.classicalarchives.com/)
* [Click Mazes](http://www.clickmazes.com/)
* [Coffee Break Arcade](https://www.coffeebreakarcade.com/)
* [CopyKat Recipes](https://copykat.com/)
* [Crazy Fads](https://www.crazyfads.com/)
* [CrazyGames.com](https://www.crazygames.com/)
* [Crosswords](crosswrd.html)
* Daily Comics: [1](https://www.washingtonpost.com/entertainment/comics/) | [2](https://www.gocomics.com/?ref=comics)
* [Daily Bridge Column](https://www.baronbarclay.com/frank-stewarts-daily-bridge-column/)
* [Daily Fuel Gauge Report](https://gasprices.aaa.com/)
* [Diary of Samuel Pepys](https://www.pepysdiary.com/)
* [Download Resources](https://download.cnet.com/)
* [Earthcam](https://www.earthcam.com/)
* [Features Page](features.html)
* [Fibble](https://fibble.xyz/)
* Free Online Games: [1](https://www.agame.com/) | [2](https://www.games.co.uk/)
* [Free Stuff](free.html)
* [Gardening Guide](https://garden.org/)
* [Grand Illusions](https://www.grand-illusions.com/)
* [Guinness World Records](https://www.guinnessworldrecords.com/)
* [Hobbies and Recreation](sports1.html)
* [Jokes and Puns](https://pun.me)
* [Late Night Jokes](https://www.nytimes.com/column/best-of-late-night)
* [LaffGaff: Short Funny Jokes](https://laffgaff.com/)
* [Luminosity Brain Games](https://www.lumosity.com/)
* [Mahjong](https://classic-mahjong.com/)
* [MSN Games](https://zone.msn.com/en-us/home)
* [MiniGames.com](https://www.minigames.com/)
* [Nutaku](https://www.nutaku.com/)
* [Names.org](https://www.names.org/)
* [Oxymoron List](http://www.oxymoronlist.com)
* [Play Flash Games](http://www.playfg.com)
* [Poetry Daily](https://poems.com/)
* [Prayer of the Day](https://www.plough.com/en/subscriptions/daily-prayer)
* [Poki](https://poki.com/)
* [PublicRadioFan.com](http://www.publicradiofan.com/)
* [Radio-Locator](https://radio-locator.com/)
* [RobinWords](https://robinwords.com)
* [Shakespearean Insulter](http://www.literarygenius.info/a2-shakespeare-insult-generator.htm)
* [Sudoku Puzzles](https://www.websudoku.com/)
* [Solitaire - Refdesk Edition](https://online-solitaire.com/refdesk)
* [TerraFly Satellite Images](http://www.terrafly.com/)
* [Time Capsule](https://dmarie.com/timecap/)
* [Tonight Show Jokes](https://www.nbc.com/the-tonight-show/photos/monologue-jokes)
* [Top10Zen](https://www.top10zen.com/)
* [TruthOrFiction.com](https://www.truthorfiction.com/)
* [Visible Earth](https://www.visibleearth.nasa.gov/)
* [What's a Dollar Worth?](https://www.usinflationcalculator.com/)
* [Wordle](https://www.nytimes.com/games/wordle/)
* [Word Square](https://www.word-square.com/)
* Your Sky
Featured Resources
X
EDITOR'S NOTE:
Refdesk is *free* to use, but is not without cost.
Please [contribute any amount](support.html) to help support us, and allow us to continue offering human curated features and [free daily editions by email](https://email.refdesk.com) every day. BONUS: Contribute $25+ for a year of Ad-Free Refdesk service as our gift to you.
Contribute
---
| | |
| --- | --- |
| SITE OF THE DAY: |
Support us
|
[New York Times: The 10 Best Books of 2023](https://www.nytimes.com/2023/11/28/books/review/best-books-2023.html)
The editors of The Times Book Review choose the best fiction and nonfiction titles this year.
| |
| --- |
| **[Site of the Day Archive](/archive/)** |
---
| | |
| --- | --- |
| FACT OF THE DAY: | |
| | |
| --- | --- |
| **[Fact of the DayArchive](/archive/fact/)** | **[Random Fact of the Day](https://www.factretriever.com/)** |
---
| | |
| --- | --- |
| THOUGHT OF THE DAY: | |
-
| | |
| --- | --- |
| **[Thought of the DayArchive](/archive/thought/)** | **[Motivational Quotes of the Day](https://www.brainyquote.com/topics/motivational)** |
---
X
BOOK OF THE MONTH
[![](https://m.media-amazon.com/images/I/A1+fWAGa6FL._SY522_.jpg)](https://amzn.to/3u6XhfM)
Get the Book!
**DEATH IN HOLY ORDERS**
By: by Charles Keating, P. D. James, et al., 2001
We love murder mystery books, but too many seem trivial: a cute plot and setting, but no evidence that the author was deeply involved in creating a special reading experience. Discovering P.D. James changed that for us. She wrote a dozen books in her life, published more than 20 years ago. Her books are wonderful! We found them clear, erudite, and involving without being silly. They are generally set in the southeast part of England. We just finished DEATH IN HOLY ORDERS and strongly recommend it, and all others by P.D. James.
**[Book of the Month Archive](/archive/book/)**
---
ARTICLE OF THE DAY: provided by [The Free Dictionary](https://www.thefreedictionary.com) [Archive >>](https://www.thefreedictionary.com/_/archive.htm)
---
THIS DAY IN HISTORY: provided by [The Free Dictionary](https://www.thefreedictionary.com) [Archive >>](https://www.thefreedictionary.com/_/archive.htm)
---
MORE THIS DAY IN HISTORY:
[Associated Press](https://apnews.com/hub/today-in-history) |
[BBC](https://news.bbc.co.uk/onthisday/) |
[History Channel](https://www.history.com/this-day-in-history) |
[HistoryNet](https://www.historynet.com/today-in-history) |
[OnThisDay.com](https://www.onthisday.com/) |
[InfoPlease](https://www.infoplease.com/dayinhistory) |
[Library of Congress](https://www.loc.gov/item/today-in-history/may-04/) |
[New York Times](https://www.nytimes.com/learning/general/onthisday/index.html)
---
TODAY'S BIRTHDAY: provided by [The Free Dictionary](https://www.thefreedictionary.com) [Archive >>](https://www.thefreedictionary.com/_/archive.htm)
---
MORE TODAY'S BIRTHDAYS:
[AP](https://apnews.com/hub/today-in-history) |
[Famous Birthdays](http://www.famousbirthdays.com/today.cgi) |
[InfoPlease](https://www.infoplease.com/birthday) |
[OnThisDay.com](https://www.onthisday.com/today/birthdays.php)
---
TODAY'S PICTURES:
[Arizona Highways](https://www.arizonahighways.com/category/photo-day) |
[Astronomy Picture of the Day](https://apod.nasa.gov/apod/astropix.html) |
[Earth's Current Temps/Clouds](https://www.ssec.wisc.edu/data/comp/latest_cmoll.gif) |
[Earth Observatory: Image of the Day](https://go.nasa.gov/3Aai8h4) |
[Earth Science Picture of the Day](https://epod.usra.edu/) |
[GoPro](https://www.instagram.com/gopro/) |
[Latest Mars Images](https://mars.nasa.gov/mer/index.html) |
[Latest Saturn Images](https://www.nasa.gov/mission_pages/cassini/main/index.html) |
[NASA EPIC::DSCOVR Daily Satellite Images](https://epic.gsfc.nasa.gov) |
[NASA Image of the Day](https://www.nasa.gov/multimedia/imagegallery/) |
[NASA Visible Earth](https://www.visibleearth.nasa.gov/) |
[Nat. Geographic: Photo of the Day (subscription)](https://www.nationalgeographic.com/photography/photo-of-the-day/) |
[NOAA Image of the Day](https://www.nesdis.noaa.gov/real-time-imagery/imagery-collections/image-of-the-day) |
[Optics Picture of the Day](https://www.atoptics.co.uk/opod.htm) |
[Reuters Pictures of the Week](https://www.reuters.com/news/pictures) |
[Telegraph Pictures of the Day (subscription)](https://www.telegraph.co.uk/news/pictures/) |
[TIME: Photography](https://time.com/section/lightbox/) |
[TIME: LightBox](https://time.com/section/lightbox/) |
[Top News Photos: Yahoo](https://news.yahoo.com/tagged/photos/) |
[Wash. Post Day in Photos](http://www.washingtonpost.com/wp-dyn/content/photo/?nav=globetop) |
[Weather Forecast Image (NOAA)](https://www.wpc.ncep.noaa.gov/noaa/noaa.gif) |
[Weather Picture of the Day](https://www.nesdis.noaa.gov/) |
[Webcam Index](https://www.earthcam.com/)
---
| |
| --- |
| WORD OF THE DAY:
provided by [The Free Dictionary](https://www.thefreedictionary.com)
[Archive >>](https://www.thefreedictionary.com/_/archive.htm)
TABLE.WordOfTheDay {border: 1px blue solid}
TABLE.WordOfTheDay TD.WoDLeft {font: bold 10pt Arial}
TABLE.WordOfTheDay TD {font: 10pt Arial}
#wod\_hw {font: 1.6em Arial}
|
MORE WORD OF THE DAY:
* [A.Word.A.Day](https://www.wordsmith.org/words/today.html)
* [Analogy of the Day](https://www.infoplease.com/analogies)
* [Daily Word Quiz](https://www.factmonster.com/schoolword)
* [Dictionary.com Word of the Day](https://www.dictionary.com/e/word-of-the-day/)
* [Merriam-Webster](https://www.merriam-webster.com/word-of-the-day)
* [New York Times](https://www.nytimes.com/column/learning-word-of-the-day)
* [Word Game of the Day](https://www.merriam-webster.com/word-games)
DAILY DIVERSIONS:
[99U.com](https://99u.adobe.com/) |
[AARP Games Page](https://games.aarp.org/) |
[Aeon](https://aeon.co/) |
[Arts & Letters Daily](https://aldaily.com/) |
Book Review: [1](https://www.barnesandnoble.com/review/) - [2](https://www.bookforum.com/) |
[Brain Games](https://stayingsharp.aarp.org/about/brain-health/games/) |
[Brain Teasers](https://www.internet4classrooms.com/brain_teasers.htm) |
[Chess Games](https://www.chess.com/) |
[Composers Datebook](https://www.yourclassical.org/programs/composers-datebook/episodes) |
Comics: [1](https://www.washingtonpost.com/entertainment/comics/) - [2](https://www.gocomics.com/?ref=comics) |
[Crosswords](crosswrd.html) |
[Current Sky Information](https://www.cfa.harvard.edu/skyreport) |
[Daily Almanac](quote.html) |
[Daily Cryptogram](https://cryptograms.puzzlebaron.com/) |
[Daily Cryptoquote](http://www.threadbender.com/) |
[Daily Download](https://download.cnet.com/) |
[Daily Haiku](https://haiku.mannlib.cornell.edu/) |
[Daily Humor: Reader's Digest](https://www.rd.com/jokes/) |
[Daily Jigsaw Puzzle](http://www.jigzone.com/puzzles/) |
[Digital Jigsaw Puzzles](https://thejigsawpuzzles.com) |
[Daily Word Jumble](https://fun.chicagotribune.com/game/tca-jumble-daily) |
[Daily Writing Tips](https://www.dailywritingtips.com/category/misused-words/) |
[Events, Births, History](http://www.scopesys.com/today/) |
[FactSlides: Random Facts](http://www.factslides.com/) |
[Famous People Born Today](https://www.thefamouspeople.com/) |
[Games for the Brain](https://www.gamesforthebrain.com/) |
[Google Sightseeing](http://www.googlesightseeing.com/) |
[Horoscope Resources](horoscps.html) |
[Late Night Jokes](https://www.nytimes.com/column/best-of-late-night) |
[Lottery Results](https://www.lotteryusa.com/) |
Medical News: [1](https://www.medpagetoday.com/) - [2](https://www.medicaldaily.com/) |
[Mix (Formerly StumbleUpon)](https://www.mix.com) |
Moon Phases
[1](https://www.moonconnection.com/moon_phases_calendar.phtml) -
[2](https://moonphases.org/) |
[Motivational Quotes of the Day](https://www.brainyquote.com/topics/motivational) |
[Movies](https://www.imdb.com/) |
[Netflix](https://www.netflix.com/) |
[Old Farmer's Almanac](https://www.almanac.com/) |
[Poetry Daily](https://poems.com/) |
[Quote of the Day](https://www.brainyquote.com/quote_of_the_day) |
[Random Wikipedia Article](https://en.wikipedia.org/wiki/Marq_de_Villiers) |
[Science Daily](https://www.sciencedaily.com/) |
[SciTech Daily Review](https://scitechdaily.com/) |
[Sudoku Puzzles](https://www.websudoku.com/) |
[Sun/Moon Rise & Set](https://www.almanac.com/astronomy/sun-rise-and-set) |
[The Awesome Daily](https://theawesomedaily.com/) |
[This Day In Music](https://www.thisdayinmusic.com/) |
[This Day In Country Music](http://www.thisdayincountrymusic.com/) |
[Today I Found Out](http://www.todayifoundout.com/) |
[Today In Earthquake History](https://earthquake.usgs.gov/learn/today/) |
[Today in History](https://www.loc.gov/item/today-in-history/may-04/) |
[Today In Jazz History](https://www.allaboutjazz.com/php/facts.php) |
[Today's Cryptoquote](http://www.eastoftheweb.com/cgi-bin/top_scores.pl?game=cryptoquote) |
[Tonight's Sky](https://earthsky.org/tonight) |
[Top 100 Bestseller Books](https://www.barnesandnoble.com/b/books/_/N-1fZ29Z8q8) |
[Top Most Popular Websites](http://www.ebizmba.com/articles/most-popular-websites) |
[Top Social Networking Sites](http://www.ebizmba.com/articles/social-networking-websites) |
[TV](https://www.tvguide.com/) |
[Wordle](https://www.nytimes.com/games/wordle/) |
[Your Sky](http://www.fourmilab.to/yoursky/) |
[Just For Fun >>](#fun)
TODAY'S POTPOURRI:
• Daily Trivia: [Random Trivia Generator](https://www.randomtriviagenerator.com/) |
[Trivia Today](https://www.triviatoday.com/)
• Computer Virus List: [McAfee](https://www.mcafee.com/enterprise/en-us/threat-center.html) |
[Symantec](https://www.broadcom.com/support/security-center) |
[Trend Micro](https://www.trendmicro.com/en_us/forHome.html)
• Health: [ABC](https://abcnews.go.com/health) |
[BBC](https://www.bbc.co.uk/news/health) |
[Breaking Medical News](https://www.medpagetoday.com/) |
[CNN](https://www.cnn.com/health) |
[WebMD](https://www.webmd.com/news/) |
[Yahoo](https://www.yahoo.com/lifestyle/tagged/health)
• Science: [AP](https://news.yahoo.com/science/) |
[BBC](https://www.bbc.co.uk/news/science_and_environment) |
[Earth & Sky](https://earthsky.org/) |
[NASA](https://science.nasa.gov/) |
[NBCNews](https://www.nbcnews.com/tech-media) |
[NewScientist.com](https://www.newscientist.com/) |
[Yahoo](https://news.yahoo.com/science/) |
[Space.com](https://www.space.com)
• Technology: [ABC](https://abcnews.go.com/technology) |
[CNET](https://www.cnet.com/) |
[CNN](https://www.cnn.com/business/tech) |
[InfoWorld](https://www.infoworld.com/) |
[PC Magazine](https://www.pcmag.com/) |
[PC World](https://www.pcworld.com/) |
[USA Today](https://www.usatoday.com/tech/) |
[Yahoo](https://news.google.com/news/section?cf=all&pz=1&topic=tc&siidp=6ff49a420e5b2b59f58b98686ea8d58f6f46&ict=ln) |
[ZDNet](https://www.zdnet.com)
• Misc: [Yahoo Answers](https://answers.yahoo.com/) |
[Born on Today](https://www.onthisday.com/today/birthdays.php) |
[Crossword](https://www.bestcrosswords.com/) |
[Daily Motivator](https://www.greatday.com/motivate/) |
[EPIC](https://www.epic.org/) |
[Good News](http://www.dailygood.org) |
[Music](https://www.usatoday.com/life/music/) |
[SciTech Review](https://scitechdaily.com/) |
[Internet Health Report](https://www.dynatrace.com/platform/digital-experience-monitoring/?vehicle_name=internetpulse.net) |
TEST PREPARATION:
* [ASVAB Prep](https://asvabadvantage.com/asvab-practice-test/)
* [DLAB Prep](https://dlabprep.com/)
* [CPA/CMA/CFA Test Prep](https://www.efficientlearning.com/)
* [Free CNA Exam Cram Practice Test](https://cna.plus/)
* [Free GRE Online Practice Test](http://www.princetonreview.com/grad/free-gre-practice-test.aspx)
* [GRE Test Prep](http://www.princetonreview.com/grad/gre-test-preparation.aspx)
* [LSAT Sample Questions](https://www.getprepped.com/practice-lsat-sample-questions/)
* [MCAT Prep](https://www.mcat-prep.com/mcat-sample-questions/)
* [MAT Prep](https://www.pearsonassessments.com/graduate-admissions/mat/about.html?tab=preparing-for-the-mat#preparing-for-the-mat)
* [Free Online Test Prep](http://www.number2.com/index.cfm?s=4zg5qaSrlPSQCYDbIy4vMvOT)
* [Official SAT Practice](https://www.khanacademy.org/sat)
* [Free SAT Prep](https://www.blinetestprep.com/)
* [SAT Preparation](https://sat.collegeboard.org/practice)
* [SAT Practice Tests](https://collegereadiness.collegeboard.org/sat/practice/full-length-practice-tests)
* [SAT Preparation Center](https://collegereadiness.collegeboard.org/sat/practice)
* [Spelling Bee](https://www.visualthesaurus.com/bee/)
* [Test Prep Review](https://www.testprepreview.com/)
* [Weekly News Quiz: NYT](https://www.nytimes.com/column/learning-news-quiz)
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Facts Search Desk
**Content Resources:**
| | |
| --- | --- |
|
Reuters/AP Headlines
|
Fact Monster
|
| | |
| --- | --- |
|
|
Medical Dictionary
|
| | |
| --- | --- |
|
• [Dictionary.com](https://www.dictionary.com/)
• [Law Dictionary](https://www.nolo.com/dictionary)
• [Google Translate](https://translate.google.com/) |
Bartleby.com
|
**Translation Dictionaries** ( one word only, e.g. fact )
| | |
| --- | --- |
|
English to Spanish
|
English to German
|
| | |
| --- | --- |
|
English to Italian
|
English to French
|
MEDIA FACT CHECKS:
[Accuracy In Media](https://www.aim.org/) -
[Fair](https://fair.org/) -
[Media Matters](https://www.mediamatters.org/studies) -
[Politifact](https://www.politifact.com/) -
[Snopes](https://www.snopes.com/)
SEARCH ENGINES:
[Ask.com](https://www.ask.com/) -
[Bing](https://www.bing.com/) -
[Dogpile](https://www.dogpile.com/) -
[DuckDuckGo](https://duckduckgo.com) -
[Google](https://www.google.com/) -
[HotBot](https://www.hotbot.com/) -
[ixquick](https://www.startpage.com/) -
[Looksmart](https://www.looksmart.com/) -
[Pipl](https://pipl.com/) -
[Startpage](https://startpage.com) -
[Yahoo!](https://search.yahoo.com/) -
[More >>](newsrch.html)
Current News / Weather / Business / Sports
• **Headlines:**
[1st Headlines](https://www.1stheadlines.com/) -
[AP Wire](https://apnews.com/hub/ap-top-news) -
[Business](https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=b&ict=ln) -
[Entertainment](https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=e&ict=ln&siidp=851d9d0dc23b1f3f2d05f8274320e9f4d645) -
[Health](https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=m&ict=ln&siidp=851d9d0dc23b1f3f2d05f8274320e9f4d645) -
[Science](https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=snc&ict=ln&siidp=851d9d0dc23b1f3f2d05f8274320e9f4d645) -
[Sports](https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=s&ict=ln&siidp=851d9d0dc23b1f3f2d05f8274320e9f4d645) -
[Technology](https://news.google.com/news/section?pz=1&cf=all&ned=us&topic=tc&ict=ln&siidp=851d9d0dc23b1f3f2d05f8274320e9f4d645) -
[UPI Headlines](https://www.upi.com/) -
[USA Today](https://www.usatoday.com/news/) -
[More >>](https://news.google.com/news)
---
• **Weather:**
[AccuWeather Service](https://www.accuweather.com/) -
[CNN Weather](https://www.cnn.com/weather) -
[FEMA News Releases](https://www.fema.gov/news-releases) -
[Intellicast](https://www.wunderground.com/maps/radar/current) -
[National Hurricane Center](https://www.nhc.noaa.gov/) -
[National Storm Warnings](https://www.nws.noaa.gov/warnings.php) -
[National Weather Service](https://www.weather.gov/) -
[USA Today Weather](https://www.usatoday.com/weather/) -
[Weather Channel](https://weather.com/) -
[Yahoo! Weather](https://www.yahoo.com/news/weather/) -
[More >>](weath1.html)
---
• **News:**
[ABC](https://abcnews.go.com/) -
[AFP](https://www.afp.com/en) -
[AP](https://apnews.com/hub/ap-top-news) -
[BBC](https://www.bbc.co.uk/news) -
[Bloomberg](https://www.bloomberg.com/)
[CBC](http://www.cbc.ca/news/) -
[CBS](https://www.cbsnews.com/) -
[CNN](https://www.cnn.com/) -
[CTV](https://www.ctvnews.ca/) -
[DailySource](https://www.dailysource.org/) -
[Excite](https://www.excite.com/news) -
[FOX](https://www.foxnews.com/) -
[Google](https://news.google.com/) -
[MSN](https://www.msn.com/en-us/) -
[MSNBC](https://www.msnbc.com/) -
[Middle East News](mideastnews.html) -
[NPR](https://www.npr.org/sections/news) -
[NBC](https://www.nbcnews.com/) -
[NYT](https://www.nytimes.com/) -
[NewsNow](https://www.newsnow.co.uk/h/) -
[Reuters](https://www.reuters.com/) -
[Sky News](https://news.sky.com/) -
[UPI](https://www.upi.com/) -
[USA Today](https://www.usatoday.com/news/) -
[WNN](https://wn.com/) -
[Wall Street Journal](https://www.wsj.com/) -
[Wash. Times](https://www.washingtontimes.com/) -
[Wash. Post](https://www.washingtonpost.com/) -
[Yahoo](https://news.yahoo.com/) -
[More >>](features.html#news)
---
• **Newspapers:**
[Atlanta Journal-Constitution](https://www.ajc.com/) -
[Arizona Republic](https://archive.azcentral.com/arizonarepublic/) -
[Austin American-Statesman](https://www.statesman.com/) -
[Baltimore Sun](http://www.sunspot.net/news/) -
[Boston Globe](https://www.bostonglobe.com/) -
[Chicago Sun-Times](https://chicago.suntimes.com/) -
[Chicago Tribune](https://www.chicagotribune.com/) -
[Christian Science Monitor](https://www.csmonitor.com/) -
[Cleveland Plain Dealer](https://www.cleveland.com/plaindealer/) -
[Dallas Morning News](https://www.dallasnews.com/) -
[Denver Post](https://www.denverpost.com/) -
[Detroit Free Press](https://www.freep.com/) -
[East Valley Tribune](https://www.eastvalleytribune.com/) -
[Houston Chronicle](https://www.chron.com/) -
[Los AngelesTimes](https://www.latimes.com/) -
[Miami Herald](https://www.miamiherald.com/) -
[Minneapolis Star Tribune](https://www.startribune.com/) -
[New Orleans Times-Picayune](https://www.nola.com/) -
[Newark Star-Ledger](https://www.nj.com/starledger/) -
[New York Daily News](https://www.nydailynews.com/) -
[New York Post](https://nypost.com/) -
[New York Times](https://www.nytimes.com/) -
[Newsday](https://www.newsday.com/) -
[Philadelphia Inquirer](https://www.inquirer.com/) -
[Pittsburgh Post-Gazette](https://www.post-gazette.com/) -
[San Diego Union-Tribune](https://www.sandiegouniontribune.com/) -
[San Francisco Chronicle](https://www.sfgate.com/) -
[St. Louis Post-Dispatch](https://www.stltoday.com/) -
[Seattle Times](https://www.seattletimes.com/) -
[Tampa Bay Times](https://www.tampabay.com/) -
[USA Today](https://www.usatoday.com/) -
[Washington Post](https://www.washingtonpost.com/) -
[Washington Times](https://www.washingtontimes.com/) -
[More >>](paper.html)
---
• **International News:**
[Afghanistan News](/asia.html#afghan) -
[Al Jazeera English](https://www.aljazeera.com/) -
[Asahi Shimbun](http://www.asahi.com/english/) -
[Asia Today](http://www.asiatoday.com) -
[Canada News](http://www.canada.ca/news) -
[China Daily](http://www.chinadaily.com.cn/) -
[Haaretz Daily](https://www.haaretz.com/) -
[Globe and Mail](https://www.theglobeandmail.com/) -
[Guardian](http://www.guardian.co.uk/) -
[Irish Times](https://www.irishtimes.com/) -
[Tass Russian News](https://tass.com/) -
[Japan Times](https://www.japantimes.co.jp/) -
[Jerusalem Post](https://www.jpost.com/) -
[Kyodo News](https://english.kyodonews.jp/login) -
[Le Monde](https://www.lemonde.fr/) -
[Lebanon Daily Star](http://www.dailystar.com.lb/) -
[London Times](http://www.timesonline.co.uk/?999) -
[London Telegraph](https://www.telegraph.co.uk/) -
[People's Daily](http://english.peopledaily.com.cn/) -
[Pravda](https://www.pravdareport.com/) -
[Sydney Morn. Herald](https://www.smh.com.au/) -
[Seoul Times](https://theseoultimes.com/ST/index.html) -
[Sky News](https://news.sky.com/) -
[Taipei Times](https://www.taipeitimes.com/) -
[WorldNews.com](https://wn.com/) -
[World Press Review](https://www.worldpress.org/) -
[Xinhua](http://www.xinhuanet.com/english/index.htm) -
[More >>](paper.html)
---
• **Business News:**
[Barrons](https://www.barrons.com/) -
[Bloomberg](https://www.bloomberg.com/) -
[CNBC](https://www.cnbc.com/) -
[CNN/Money](https://www.cnn.com/business) -
[Economist](https://www.economist.com/index.html) -
[Financial Times](http://www.ft.com/home/us) -
[Forbes](https://www.forbes.com/) -
[Fortune](https://fortune.com/) -
[Fox Business](https://www.foxbusiness.com/) -
[IBTimes.com](https://www.ibtimes.com) -
[Investing.com News](https://www.investing.com/) -
[Investor's Business Daily](https://www.investors.com/) -
[Kiplinger](https://www.kiplinger.com/) -
[MSN Money](https://www.msn.com/en-us/money/) -
[Morningstar](https://www.morningstar.com/) -
[Motley Fool](https://www.fool.com/) -
[NBC Business](https://www.nbcnews.com/business/) -
[Red Herring](https://www.redherring.com/) -
[SmartMoney](https://www.marketwatch.com/?showsmscrim=true) -
[TheStreet.com](https://www.thestreet.com/) -
[WSJ MarketWatch](http://www.marketwatch.com/news/default.asp?siteid=&avatar=seen) -
[More >>](http://www.headlinespot.com/subject/business/)
---
• **Sports:**
[CBS Sports](https://www.cbssports.com/) -
[ESPN](https://www.espn.com/) -
[Golf Channel](https://www.golfchannel.com/) -
[Inside Hoops](http://www.insidehoops.com/) -
[NASCAR.com](https://www.nascar.com/) -
[MLB.com](https://www.mlb.com/) -
[NBA.com](https://www.nba.com/) -
[NFL.com](https://www.nfl.com/) -
[Sports Illustrated](https://www.si.com/) -
[More >>](http://www.headlinespot.com/subject/sports/)
---
• **Magazines:** [Atlantic](https://www.theatlantic.com/)
[Business Week](https://www.bloomberg.com/businessweek) -
[Economist](https://www.economist.com/) -
[Harper's](https://harpers.org/) -
[Nat. Review](https://www.nationalreview.com/) -
[Newsweek](https://www.newsweek.com/) -
[New Yorker](https://www.newyorker.com/) -
[People](https://people.com/) -
[Reader's Digest](https://www.rd.com/) -
[Salon](https://www.salon.com/) -
[Slate](https://slate.com/) -
[Sci. Amer.](https://www.scientificamerican.com/) -
[Time](https://time.com/) -
[TV Guide](https://www.tvguide.com/) -
[US News](https://www.usnews.com/) -
[More >>](http://www.headlinespot.com/type/magazines/)
---
• **Net/Tech News:** [c|net](https://www.cnet.com/news/) -
[CNN Technology](https://www.cnn.com/business/tech) -
[ClickZ](https://www.clickz.com/) -
[Net News](http://www.internetnews.com/) -
[Slashdot](https://slashdot.org/) -
[Wired](https://www.wired.com/) -
[ZDNet](https://www.zdnet.com/) -
[More >>](http://www.headlinespot.com/subject/technology/)
---
• **Miscellaneous:** [Arts Journal](https://www.artsjournal.com/) -
[Editorials](http://www.headlinespot.com/opinion/oped/) -
First Chapter: [NYT](https://www.nytimes.com/books/first/first-index.html) -
[WP](https://www.washingtonpost.com/wp-srv/style/books/chapterone.htm) -
[Movie Reviews and Research](https://www.imdb.com/) -
[Movie Reviews](https://www.mrqe.com/) -
[TV Reviews](https://www.rottentomatoes.com/top-tv/) -
[Video Reviews](https://www.ign.com/) -
[More >>](features.html#feat)
COLUMNISTS & COMMENTATORS:
[Eric Alterman](https://www.thenation.com/authors/eric-alterman/) |
[Dave Barry](https://blogs.herald.com/dave_barrys_blog/) |
[David Brooks](https://www.nytimes.com/column/david-brooks) |
[Tina Brown](https://www.thedailybeast.com/author/tina-brown.html) |
[Ron Brownstein](https://www.theatlantic.com/author/ronald-brownstein/) |
[Pat Buchanan](https://buchanan.org/blog/columns) |
[Ann Coulter](https://anncoulter.com/) |
[Maureen Dowd](https://www.nytimes.com/column/maureen-dowd) |
[E.J. Dionne, Jr.](https://www.washingtonpost.com/people/ej-dionne-jr/) |
[Thomas Friedman](https://www.nytimes.com/column/thomas-l-friedman) |
[John Fund](https://www.nationalreview.com/author/john-fund/) |
[Michael Gerson](https://www.washingtonpost.com/people/michael-gerson/) |
[Paul Krugman](https://www.nytimes.com/column/paul-krugman) |
[Howard Kurtz](https://www.foxnews.com/person/k/howard-kurtz.html) |
[Mark Levin](https://www.marklevinshow.com/) |
[Michelle Malkin](https://thenewamerican.com/contributor/michelle-malkin/) |
[Doyle McManus](https://www.latimes.com/people/doyle-mcmanus) |
[John Nichols](https://www.thenation.com/authors/john-nichols/) |
[Peggy Noonan](https://www.wsj.com/news/author/peggy-noonan) |
[Kathleen Parker](https://www.washingtonpost.com/people/kathleen-parker/) |
[Thomas Sowell](https://townhall.com/columnists/thomassowell/) |
[John Stossel](https://www.johnstossel.com/) |
[George Will](https://www.washingtonpost.com/people/george-f-will/) |
[Walter Williams](http://walterewilliams.com/posts/) |
[Fareed Zakaria](https://www.washingtonpost.com/people/fareed-zakaria)
OPINION & EDITORIALS:
[Chicago Tribune](https://www.chicagotribune.com/opinion/) |
[Houston Chronicle](https://www.houstonchronicle.com/opinion/) |
[San Jose Mercury News](https://www.mercurynews.com/opinion/) |
[LA Times](https://www.latimes.com/opinion) |
[Miami Herald](https://www.miamiherald.com/opinion/) |
[New York Times](https://www.nytimes.com/section/opinion) |
[San Francisco Chronicle](https://www.sfgate.com/columns/editorials/) |
[USA Today](https://www.usatoday.com/opinion/) |
[WSJ](https://www.wsj.com/news/opinion) |
[Washington Post](https://www.washingtonpost.com/opinions/?hpid=hp__%3A&itid=hp_rhp___%3A) |
[Yahoo Op/Ed](https://news.yahoo.com/)
Refdesk Subject Categories
**[REFERENCE DESK](refdsk.html)
[REFDESK SITE MAP](toc.html)**
| | | |
| --- | --- | --- |
| **Facts/Internet**
[Beginner's Guides](factbeg.html)
[Computer Graphics](compgrah.html)
[Computer Hardware](comphard.html)
[Computer Software](compsoft.html)
[Devices/Gadgets](gadgets.html)
[Download Page](download.html)
[Free Stuff](free.html)
[Fun Stuff](fun.html)
[Hobbies/Recreation](sports1.html)
[Libraries](factlib.html)
[Magazines](mag.html)
[Phone Book](factphon.html)
[Net Resources](factnet.html)
[Reference Shelves](shelves.html)
[Time and Date](factdate.html)
[Weights/Measures](factmeas.html)
**Philosophy**
[Philosophy](philos.html)
**Religion**
[World Religions](factrel.html)
| **Social Sciences**
[Business/Career](business.html)
[Crime/Law Enforce.](crime.html)
[Education](educate.html)
[Environment](nature.html)
[Family Matters](fammat.html)
[Food/Recipes](food.html)
[Health](health.html)
[Homework Helper](homework.html)
[Kids Stuff](kids.html)
[Language Learning](language.html)
[Legal Resources](factlaw.html)
[Personal Finances](finance.html)
[Seniors Online](seniors.html)
[Sports](sports.html)
[Women's Issues](women.html)
**Language**
[Dictionaries](factdict.html)
[Encyclopedias](factency.html)
[Grammar/Style](factgram.html)
[Quotations](factquot.html)
**Natural Sciences**
[Science](factsci.html)
[Space/Astronomy](space.html)
[Weather](weath1.html)
| **Applied Sciences**
[Automotive](autos.html)
[Aviation](flying.html)
[Career](business.html)
[Mental Health](mental.html)
[Military](military.html)
[Pets/Animals](pets.html)
**Art/Entertainment**
[Arts & Culture](culture.html)
[Movies](movies.html)
[Music](music.html)
[Photography](photo.html)
**Literature**
[Books/Literature](books.html)
[Electronic Texts](factelec.html)
**Geography/History**
[Biography](factbiog.html)
[Genealogy](factgene.html)
[Geography](geo.html)
[History](facthist.html)
[Maps](factmaps.html)
[Population](factpop.html)
[Travel](travel.html)
|
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Internet Search Resources
[![Google](google-75x32.png)](https://www.google.com/)
td.gsc-input {
border: 1px solid gray;
border-radius: 3px;
margin-bottom: unset;
font-size: 0.75em;
}
div#gsc-iw-id1.gsc-input-box {
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td.gsib\_a {
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margin-left: 4px;
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[Maps](https://maps.google.com/) |
[News](https://news.google.com/) |
[Calendar](https://www.google.com/calendar) |
[Tips/Tricks](https://support.google.com/websearch/answer/134479?hl=en) |
[More >>](https://www.google.com/intl/en/options/)
[Clear Browser Cache/History](https://www.pcmag.com/how-to/how-to-clear-your-cache-on-any-browser)
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[![Bing](bing.png)](https://www.bing.com/)
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[Maps](https://www.bing.com/maps/) | [News](https://www.bing.com/news)
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| search |
[News](https://news.yahoo.com/?u)
---
[![YouTube](yt.png)](https://www.youtube.com/)
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| search |
[Help](https://help.youtube.com/support/youtube/)
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amzn\_assoc\_width = '125';
amzn\_assoc\_height = '125';
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| **Search for Books & Music:** |
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SEARCH WIKIPEDIA:
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[Random Wikipedia Article](https://en.wikipedia.org/wiki/Special:Random)
---
SEARCH GOOGLE NEWS:
(e.g., Terror)
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| search |
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GET STOCK QUOTES:
Enter Stock Symbol / [Symbol Lookup](https://finance.yahoo.com/)
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| search |
[Dow Jones](https://finance.yahoo.com/q?s=%5EDJI) |
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SOCIAL NETWORKS:
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DICTIONARY:
function getValue(term){
if(document.query.elements[0].checked == true){document.location.href = "http://www.merriam-webster.com/dictionary/" + term;}
else if(document.query.elements[1].checked == true){document.location.href = "https://www.merriam-webster.com/thesaurus/" + term;}}
Merriam-Webster Online
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| | Dictionary |
---
[TheFreeDictionary](https://www.thefreedictionary.com "ThefreeDictionary.com"):
Dictionary/Thesaurus
Computing Dictionary
Medical Dictionary
Legal Dictionary
Financial Dictionary
Acronyms
Wikipedia Encyclopedia
Columbia Encyclopedia
---
PEOPLE WHITE PAGES RESOURCES:
* [50States.com](https://www.50states.com/whitepages/)
* [AnyWho.com](https://www.anywho.com/whitepages)
* [Intelius.com](https://www.intelius.com/)
* [Reverse Phone Lookup](https://www.usphonebook.com/)
* [Reverse Address Lookup](https://www.addresses.com/reverse-address)
* [WhitePages.com](https://www.whitepages.com/person)
* [Yahoo.com](http://search.yahoo.com/web?fr=people)
---
BUSINESS YELLOW PAGES RESOURCES:
* [50States.com](https://www.50states.com/yellowpages/)
* [AnyWho.com](https://www.anywho.com/yellow-pages)
* [WhitePages.com](https://www.whitepages.com/business)
* [YellowBook.com](https://www.yellowbook.com/)
* [YellowPages.com](https://www.yellowpages.com/)
* [Yahoo.com](https://local.yahoo.com)
DRIVING DIRECTIONS:
[MapQuest.com](https://www.mapquest.com/): [Help](https://help.mapquest.com/)
| |
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| FROM: |
| Address or Intersection: |
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Canada
United States
|
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| TO: |
| Address or Intersection: |
| |
| City: |
| |
| State/Province: | ZIP Code: |
| | |
| Country: |
|
Canada
United States
|
|
|
---
* [MapMyRide Cycling Maps](https://www.mapmyride.com/)
* [Maps: USA & World](https://www.nationalgeographic.com/maps/)
* [Google Maps](https://maps.google.com/)
* [HERE WeGo](https://wego.here.com/)
MISC. RESOURCES:
* [9/11 Commission Full Report](https://9-11commission.gov/report/)
* [America Responds](attack.html)
* [DoD News Releases](https://www.defense.gov/Newsroom/releases/)
* [FBI News Releases](https://www.fbi.gov/news/pressrel)
* [Middle East News Resources](mideastnews.html)
* [UN News Service](https://news.un.org/en/)
Facts-at-a-Glance
* [100 Milestone Documents](http://www.ourdocuments.gov/content.php?page=milestone)
* [10-10 Phone Rates: Comps](https://www.voipreview.org/)
* [U.S. Census Statistics](https://www.census.gov/)
* College Rankings: [1](https://www.usnews.com/best-colleges/rankings/national-universities) |
[2](http://www.forbes.com/top-colleges/list/) |
[3](http://www.payscale.com/best-colleges)
* [50States.com](https://www.50states.com/)
* [U.S. Constitution](https://constitutioncenter.org/interactive-constitution)
---
* [800-numbers.net](https://www.800-numbers.net/)
* [A Bell Tolls: LD Rate Comps](https://abtolls.com/)
* [Acronym Finder](https://www.acronymfinder.com)
* [Actuarial Life Table](https://www.ssa.gov/oact/STATS/table4c6.html)
* [DHL](https://www.dhl.com/us-en/home.html)
* Airline Flight Tracker: [1](https://flightaware.com/) |
[2](https://www.flightview.com/TravelTools/) |
[3](http://www.flightstats.com/go/FlightTracker/flightTracker.do) |
[4](https://flightwise.com/)
* [Airline Toll-Free Numbers](http://www.tollfreeairline.com/)
* [Airport Code Lookup](/airport_codes.html)
* [Airport Security Wait Times](https://www.dhs.gov/how-do-i/check-wait-times)
* [American Fact Finder](https://data.census.gov/cedsci/)
* [Annual Credit Report (Free)](https://www.annualcreditreport.com/cra/index.jsp)
* [Area Code Finder](http://www.fonefinder.net/)
* [Area Code Listing](https://www.bennetyee.org/ucsd-pages/area.html)
* [Area Code Map](https://www.allareacodes.com/area-code-map.htm)
* [AreaVibes: City Data](https://www.areavibes.com/)
* [BMI Calculator](https://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmi-m.htm)
* [Bible: Douay-Rheims Cath. Ver.](http://www.drbo.org/)
* [Bible: Hebrew Ver.](https://www.mechon-mamre.org/e/et/et0.htm)
* [Bible: King James Ver.](https://www.bartleby.com/108/)
* [Biography.com](https://www.biography.com/)
* [Calculator: Day of the Week](http://www.searchforancestors.com/utility/dayofweek.html)
* [Calculators](topcalc.html)
* [Calendar: 10,000 Year](https://calendarhome.com/print-a-calendar/)
* [Calendar: Customized](https://www.timeanddate.com/calendar/custommenu.html)
* [Calendar: Days Between Dates](https://www.timeanddate.com/date/duration.html)
* [Calendar: Earth](http://www.earthcalendar.net/index.php)
* [Calendar: Perpetual](https://www.infoplease.com/calendar)
* [Canada Postal Lookup](https://www.canadapost.ca/cpo/mc/languageswitcher.jsf)
* [Chemical Elements.com](http://www.chemicalelements.com)
* [Chiefs of State](https://www.cia.gov/the-world-factbook/field/political-parties-and-leaders/)
* [CIA World Fact Book](https://www.cia.gov/the-world-factbook/)
* [City Data (USA)](http://www.city-data.com/)
* [Consumer Info](https://www.consumerworld.org/)
* [Consumer Price Index](https://www.bls.gov/cpi/)
* [Contacting Congress](https://www.usa.gov/Contact/Elected.shtml)
* [Convert Anything](https://www.onlineconversion.com/)
* [Country Calling Codes](https://en.wikipedia.org/wiki/List_of_country_calling_codes)
* [Coupons for Online Shopping](/coupons.html)
---
DICTIONARIES:
* [American Heritage](https://www.ahdictionary.com/)
* [Banking](https://www.macmillandictionary.com/us/thesaurus-category/american/general-words-relating-to-banking)
* [Compact OED](https://www.lexico.com)
* [Computing](https://www.webopedia.com/)
* [Crossword](https://www.crossword-dictionary.com/)
* [Financial](https://financial-dictionary.thefreedictionary.com)
* [High-Tech](https://www.computeruser.com/dictionary/)
* [Legal](https://www.nolo.com/dictionary)
* [Medical](https://www.medicinenet.com/script/main/hp.asp)
* [Reverse Dictionary](https://www.onelook.com/reverse-dictionary.shtml)
* [Spanish-English](https://www.spanishdict.com/)
* [Talking Dictionary](https://howjsay.com/)
* [Visual Dictionary](http://visual.merriam-webster.com/)
* [Weather Glossary](https://w1.weather.gov/glossary/)
* [More >>](factdict.html)
---
HEALTH & MEDICINE:
* [COVID-19 Coronavirus Resources](covid19.html)
* [Doctor Board Verification](https://www.certificationmatters.org/)
* [Drug Information](https://medlineplus.gov/druginformation.html)
* [Health Information](https://medlineplus.gov/)
* [Hospital Rankings](https://health.usnews.com/best-hospitals/rankings)
* [Gray's Anatomy](https://www.bartleby.com/107/)
---
ENCYCLOPEDIAS:
* [1911 Encyclopedia Britannica](http://en.wikipedia.org/wiki/Encyclopædia_Britannica_Eleventh_Edition)
* [Britannica Online](https://www.britannica.com/)
* [Canadian](https://www.thecanadianencyclopedia.ca/en)
* [Encyclopedia.com](https://www.encyclopedia.com/)
* [Encyclopedia of Life](https://eol.org/)
* [Legal](https://www.nolo.com/legal-encyclopedia)
* [Medical](https://medlineplus.gov/encyclopedia.html)
* [Weather](https://w1.weather.gov/glossary/)
* [Wikipedia](https://en.wikipedia.org/wiki/Main_Page)
* [More >>](factency.html)
---
FIND:
* [Ancestors](https://www.ancestry.com/)
* Apartments: [1](https://www.apartmentguide.com/) | [2](https://www.doorsteps.com/) | [3](https://www.rent.com/)
* [College](https://www.petersons.com/)
* [Doctor](https://doctor.webmd.com/)
* [Elected Officials](https://www.usa.gov/Contact/Elected.shtml)
* [Fact Check.org](https://www.factcheck.org/)
* [First-Aid Guide](http://www.mayoclinic.org/health/FirstAidIndex/FirstAidIndex)
* [House](https://www.realtor.com/) | [House Value](https://www.zillow.com/)
* [Lawyer](https://www.lawyers.com/)
* [Health Information](https://medlineplus.gov/)
* [Legal Information](https://lp.findlaw.com/)
* [Medical Information](https://medlineplus.gov/)
* [People](https://refdesk.whitepages.com/)
* [People Finder Guide](https://virtualchase.justia.com/wiki/people-finders/)
---
* [Flags of the World](https://www.cia.gov/the-world-factbook/references/flags-of-the-world/)
* [Foreign Words and Phrases](https://www.infoplease.com/homework-help/writing-grammar/foreign-words-and-phrases1)
* [Get Human Customer Service](https://gethuman.com/)
* [How Far Is It?](https://www.freemaptools.com/how-far-is-it-between.htm)
* [Kelley Blue Book](https://www.kbb.com/)
* Language Translator: [1](https://translate.google.com) | [2](https://www.freetranslations.org/)
* [Legal Resources](https://www.findlaw.com/)
* [Library of Congress](https://www.loc.gov/)
* [Mailbox (USPS) Locator](https://www.payphone-project.com/usps-mailboxes/index.html)
* [MedSafety Info](https://consumermedsafety.org/)
* [Merck Manual Home Edition](https://www.merckmanuals.com/home)
* [Mortgage Loan Calculator](https://www.zillow.com/mortgage-calculator/)
---
* [Newspaper Archives](https://www.loc.gov/rr/news/oltitles.html)
* [Occupational Handbook](https://www.bls.gov/ooh/)
* [Online Unit Conversion](https://www.onlineconversion.com/)
* [Physician's Desk Ref: Drugs](http://www.pdrhealth.com/home/home.aspx)
* [Postage Price Calculator](https://postcalc.usps.com/)
* [Population Clocks: US/World](https://www.census.gov/popclock/)
* [Public Records Database](https://publicrecords.onlinesearches.com/)
* [Robert's Rules of Order](https://www.bartleby.com/176/)
* [Rulers of the World](https://rulers.org/)
* [State Health Facts](https://www.kff.org/statedata/)
* [Strunk's Elements of Style](https://www.bartleby.com/141/)
* [UPS](https://www.ups.com/us/en/global.page)
* [U.S. Census Bureau](https://www.census.gov/)
* [U.S. Postal Service](https://www.usps.com/)
* [Who's Alive/Who's Dead](http://www.wa-wd.com/)
* [World Atlas/Geo. Facts](https://www.worldatlas.com/aatlas/world.htm)
* [World Time Server](https://www.worldtimeserver.com/)
* [World Time Zone Map](https://www.timeanddate.com/time/map/)
* [Yellow Pages](https://www.yellowpages.com/)
* [ZIP 4 Code Look-up](https://tools.usps.com/go/ZipLookupAction)
* [ZIP Codes: International](https://worldpostalcode.com/)
* [More >>](instant.html)
SITE INFORMATION:
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| https://refdesk.com/ |
<!DOCTYPE html>
<html>
<head>
<meta charset="UTF-8">
<title>~*~ Kirby's Dream Site !*!</title>
<!-- styles -->
<link href="/style.css?v=4" rel="stylesheet" type="text/css" media="all">
<!--<script src="snow.js"></script>-->
</head>
<body>
<!--<img class="tree" src="./tree.gif">-->
<div class="page clearfix">
<!--
<div class="welcome">
<p>Welcome to my Kirby page!
Check out the pages below! Click 'NeWs' to see recent updates and 'FrienDs' to see some links.
Poyo! ^(^_^)>
</p>
</div>
-->
<div class="nav">
<ul class="clearfix">
<!-- <li class="news-link"><a href="#news"><img src="news.png"></a></li> -->
<li class="friends-link"><a href="#friends"><img src="friends.png"></a></li>
<li class="friends-link"><a href="gifs.html"><img src="gifs.gif"></a></li>
<!-- <li class="friends-link"><a href="https://kirbysdreambook.herokuapp.com/"><img src="guestbook.gif"></a></li> -->
<li class="friends-link"><a href="about.html"><img src="about-title.gif"></a></li>
<li class="friends-link"><a href="#links"><img src="links.gif"></a></li>
</ul>
</div>
<div class="splash">
<img class="pixelated" src="kirby-victory.png" />
</div>
<div id="stages" class="stage-row">
<a class="stage-link" href="vv.html"><img src="vegetable-valley.png" /></a>
<a class="stage-link" href="ici.html"><img src="ice-cream-island.png" /></a>
<div class="row clearfix">
<a class="stage-link" href="bb.html"><img src="butter-building.png" /></a>
<div class="preview">
<p>Page preview below!</p>
<iframe src="bb.html?noAudio" frameborder="0"></iframe>
</div>
</div>
<a class="stage-link" href="gg.html"><img src="grape-garden.png" /></a>
<a class="stage-link" href="yy.html"><img src="yogurt-yard.png" /></a>
<a class="stage-link" href="oo.html"><img src="orange-ocean.png" /></a>
<a class="stage-link" href="rr.html"><img src="rainbow-resort.png" /></a>
<a class="stage-link" href="fd.html"><img src="fountain-of-dreams.png" /></a>
</div>
<!--
<div id="news" class="news">
<div class="post">
<h1>R.I.P. Kirby's Rainbow Resort?</h1>
<h2>Updated: June 28, 2020</h2>
<p>
So, I noticed <a href="http://www.kirbysrainbowresort.net/">Kirby's Rainbow Resort</a> throws a
<a href="https://developer.mozilla.org/en-US/docs/Web/HTTP/Status/500">500 error</a>, if you click through the splash page...
hope it keeps sticking around. Even without updates it's (was?) an amazing site for Kirby content.
</p>
<p>
Otherwise, I noticed I'm on the first page of <a href="https://neocities.org/browse">/browse</a>
now :O *_* which feels somewhat undeserved considering the lack of updates. Well, time to go work on the
weekend... *downing in code* blerrrggugh
</p>
</div>
<div class="post">
<h1>jooob...</h1>
<h2>Updated: February 1, 2020</h2>
<p>
Well, not only is my job busy, but I've been roped into various other things (ghosts of old projects). Maybe
that update will be done in July? LMAO.
</p>
<p>
Hoping that won't be the case, but... I won't let this very nice place die either way.
Even if the next update is in 3030!
</p>
</div>
<div class="post">
<h1>JOOOB</h1>
<h2>Updated: November 9, 2019</h2>
<p>
I found a new job ^(^_^)^ I will be a bit absent while I ramp up there, but hopeful my big update will be done
come January. ~poooooyo~
</p>
</div>
<div class="post">
<h1>Delet Board</h1>
<h2>Updated: October 15, 2019</h2>
<p>
I got rid of the slapboard because it's not being used at all and is dumb and I am bored of it.
</p>
<p>
Meanwhile, I am still looking for a jerb. BUT there are indeed plans after that and the site
WILL be updated with new Kirby content.
</p>
</div>
<div class="post">
<h1>Board Thingy v1</h1>
<h2>Update: Sometime in September</h2>
<p>
I've finished this <a href="board.html">slap board</a> type thingy.
Controls are a bit esoteric right now, but I'll try and update it again soon.
</p>
<p>
Still looking for a new jerb. I have plenty of golden kirbies though, so no worries there (...yet).
</p>
<p>
I should really open a suggestion box because I'm running out of ideas ;^_^, but maybe just hit that
<a href="https://kirbysdreambook.herokuapp.com/">guestbook</a>?
</p>
</div>
<div class="post">
<h1>Hiya!</h1>
<h2>Updated: August 4, 2019</h2>
<p>
Super excited that KDS has gotten 10k+ views! By far the most visited thing I've ever made. Thanks everyone <(^_^)^
</p>
<p>
No updates other than my job situation is up in the air, so not much time to build the site. Things on the potential feature list are:
some kind of email contact for site suggestions, guestbook needs some cleanup, and possibly more GIFs. Otherwise, I'm thinking of some kind
of lame JavaScript turn based game you can play in the browser.
</p>
<p>
Hopefully more ideas than that will come to me. Preferably visual ones. Bye for now, poyo!
</p>
</div>
<div class="post">
<h1>Done.. for now?</h1>
<h2>Updated: April 2, 2019</h2>
<p>
I believe this site is more or less complete. I don't know if I'll ever endeavor to do a full fan site because a lot of information
about Kirby is already out there. I tried to do something somewhat interesting in presentation, not necessarily a rehash of existing
walkthroughs, guides, and wikis.
</p>
<p>
Possibly more animations or some novel thing may come out of this, but nothing planned right now. Maybe I'll start doing really
bad Kirby fan art. Maybe I'll work on a different site completely different from this with different creative output.
</p>
<p>
Regardless, the site will be up here for all to see as long as possible.
POYO! Bye for now.
</p>
</div>
<div class="post">
<p>
Another quick drop... I really need to expand the site and organize more things ;^_^<br>
<a href="https://ebay.us/kZFVKx">1993 Retro Kirby plush! Only ~$2,500!</a><br>
It's seriously cute either way though.
</p>
</div>
<div class="post">
<p>Just gonna driveby post this super cute <a href="https://twitter.com/kae77p/status/1101090892666925058">Kirby cupid fanart...</a> cya later.</p>
</div>
<div class="post">
<h1>No Snow!</h1>
<h2>Updated: January 13, 2019</h2>
<p>Well Christmas has come and gone, but Kirby lives on. I still feel Christmasy tho ^_^ and hopefully will find cute Kirbys to post reflecting
that feeling.</p>
</div>
<div class="post">
<h1>Snow!</h1>
<h2>Update: December 22, 2018</h2>
<p>Added some Christmasy snow thanks to <a href="http://www.schillmania.com/projects/snowstorm/">http://www.schillmania.com/projects/snowstorm/</a>
for this gift of Christmas :3 Also changed some colors so the snow would look better.</p>
</div>
<div class="post">
<h1>Links!</h1>
<h2>Update: October 28, 2018</h2>
<p>Made a <a href="#links">links</a> section. Only one right now, BUT more to come later, so later gator.</p>
</div>
<div class="post">
<h1>About page.</h1>
<h2>Update: September 2, 2018</h2>
<p>I made an <a href="about.html">about</a> page explaining the basis of this site.</p>
<p>This homage is mostly complete, but who knows, maybe I'll keep updating it with content.</p>
</div>
<div class="post">
<h1>I now have a gaudy GIF page!</h1>
<h2>Update: September 1, 2018</h2>
<p><a href="gifs.html">Yeeeep.</a> I've been having a lot of fun updating more frequently poyo! <(^_^)></p>
</div>
<div class="post">
<h1>Guestbook!! (and bug fixes)</h1>
<h2>Update: August 26, 2018</h2>
<p>I wrote a mini-guestbook in Rails! You can see it <a href="https://kirbysdreambook.herokuapp.com/">over here</a>.</p>
<p>I also fixed some image bugs on Firefox that were making the images blurry.</p>
</div>
<div class="post">
<h1>Long time no update! Being an adult sucks!</h1>
<h2>Update: August 19, 2018</h2>
<p>Oh jeez, it's been months and months. I added a little page preview frame for the <a href="./bb.html">Bronto animations</a>.</p>
<p>Be sure to check out the lights on-off button I added to the <a href="./gg.html">Grape Garden</a> page!</p>
</div>
<div class="post">
<h1>Bronto Animations Added !</h1>
<h2>Update: November 23, 2017</h2>
<p>I added some silly animations to the <a href="./bb.html">butter bulding</a> page.</p>
</div>
<div class="post">
<h1>Version 1 Complete !!</h1>
<h2>Update: November 18, 2017</h2>
<p>
The first version of my Kirby shrine is done!
My favourite backgrounds and music from Kirby's Adventure can be found by clicking the stage splashes below.
Soon there will be more content and animations. Thank you for visting! ^(^_^)>
</p>
</div>
</div>
-->
<!-- id for future in page links when I get the time. -->
<div id="friends" class="links">
<h1>Friends of Kirby</h1>
<a href="https://exosilver.neocities.org/"><img src="./exo.gif"></a>
<a href="https://daniele63.neocities.org/"><img src="./danieles_button.jpg"></a>
</div>
<div id="links">
<h1>Links</h1>
<p>
<a href="http://www.kirbysrainbowresort.net/">Kirby's Rainbow Resort</a>
<span class="white-text">
-- Probably the longest running Kirby fansite on the web.
Walkthroughs, art, forums, music, and tons of other miscellaneous Kirby content.
</span>
<p>
<p>
<a href="https://www.nintendo.co.jp/n02/shvc/p_akfj/index.html">Official Kirby Super Star website!</a>
<span class="white-text">
-- I'm amazed it's still intact.
</span>
</p>
<p>
<strike>
<a href="http://www.meta-knight.com/">Masked Knight</a>
<span class="white-text">
-- An interesting Meta Knight shrine and fansite where I pilfered the Official KSS website link.
Worth a look!
</span>
</strike>
</p>
</div>
<div class="footie">
<h1>My Button!</h1>
<p>Exosilver made this cute button for me a while back, if you'd like to link here feel free to use it!</p>
<img src="kirbysdreamsite.gif" />
</div>
</div>
</body>
</html>
|
~\*~ Kirby's Dream Site !\*!
* [![](friends.png)](#friends)
* [![](gifs.gif)](gifs.html)
* [![](about-title.gif)](about.html)
* [![](links.gif)](#links)
![](kirby-victory.png)
[![](vegetable-valley.png)](vv.html)
[![](ice-cream-island.png)](ici.html)
[![](butter-building.png)](bb.html)
Page preview below!
[![](grape-garden.png)](gg.html)
[![](yogurt-yard.png)](yy.html)
[![](orange-ocean.png)](oo.html)
[![](rainbow-resort.png)](rr.html)
[![](fountain-of-dreams.png)](fd.html)
# Friends of Kirby
[![](./exo.gif)](https://exosilver.neocities.org/)
[![](./danieles_button.jpg)](https://daniele63.neocities.org/)
# Links
[Kirby's Rainbow Resort](http://www.kirbysrainbowresort.net/)
-- Probably the longest running Kirby fansite on the web.
Walkthroughs, art, forums, music, and tons of other miscellaneous Kirby content.
[Official Kirby Super Star website!](https://www.nintendo.co.jp/n02/shvc/p_akfj/index.html)
-- I'm amazed it's still intact.
[Masked Knight](http://www.meta-knight.com/)
-- An interesting Meta Knight shrine and fansite where I pilfered the Official KSS website link.
Worth a look!
# My Button!
Exosilver made this cute button for me a while back, if you'd like to link here feel free to use it!
![](kirbysdreamsite.gif)
| https://kirbysdreamsite.neocities.org/ |
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<meta name="rights" content="Simon Augustin">
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<META name="CREATOR" content="Mo Bechtold">
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Stinkt!
Ihr Browser unterstützt keine Frames!*fluch*
Sie müssen sich entweder einen Neueren Downloaden oder von einem anderen aus diese Seite aufrufen.
Benutzen Sie Windows 3.11? Wenn ja, laden Sie sich Internet Explorer 5 in der 16-Bit Version runter!
Wenn Sie keinen Browser runterladen können, der Frames unterstützt, warum auch immer, klicken Sie
<a href="navi.html">hier</a> für das Inhaltsverzeichnis. Damit erhalten Sie zu den meisten
Unterseiten Zugriff. Allerdings hab ich mich hier ausgetobt, um CSS zu lernen und das Ergebnis ist recht bunt. Wenn Ihr Browser keine Frames kann, wird er wohl kaum CSS können.
</noframes>
</head>
</html> |
Index
Stinkt!
Ihr Browser unterstützt keine Frames!\*fluch\*
Sie müssen sich entweder einen Neueren Downloaden oder von einem anderen aus diese Seite aufrufen.
Benutzen Sie Windows 3.11? Wenn ja, laden Sie sich Internet Explorer 5 in der 16-Bit Version runter!
Wenn Sie keinen Browser runterladen können, der Frames unterstützt, warum auch immer, klicken Sie
[hier](navi.html) für das Inhaltsverzeichnis. Damit erhalten Sie zu den meisten
Unterseiten Zugriff. Allerdings hab ich mich hier ausgetobt, um CSS zu lernen und das Ergebnis ist recht bunt. Wenn Ihr Browser keine Frames kann, wird er wohl kaum CSS können.
| http://tempect.de/senil/ |
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| https://crashland.elynx.fr/ressourcebonus/siteofficiel/ |
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</tbody>
</table>
<font size="+2"><b>Rat Behavior and Biology</b></font>
<p><font size="+1"><b><i>(Anne's rat
page)</i></b></font></p>
</center>
<p>Welcome to my website about rats. I have written a number of
articles about rat behavior and
biology. These articles are based on my study of the scientific
literature available on rats and on my own observations of rat
behavior.<br>
</p>
<p><font size="-1">
<table border="1" cellpadding="5" cellspacing="0" width="100%">
<tbody>
<tr>
<td valign="top">
<p><a href="RatBehaviorMain.htm"><b>Rat Behavior</b></a></p>
<ul>
<li><a href="norway_rat_ethogram.htm"><font size="-1">Norway
rat behavior repertoire</font></a><font size="-1"><br>
<i>Expanded articles:</i></font>
<ul>
<li><a href="Aggression.htm"><font size="-1">Aggression</font></a></li>
<li><a href="RatPlay.htm"><font size="-1">Rat play</font></a></li>
<li><a href="FoodChoices.htm"><font size="-1">How do rats
choose what to eat?</font></a></li>
<li><a href="WhyDoRatsPee.htm"><font size="-1">Why do rats
pee everywhere?</font></a><font size="-1"><br>
Also:</font> <a href="UrineMarking.htm"><font size="-1">Urine marking</font></a></li>
<li><a href="infanticide.htm"><font size="-1">Infanticide</font></a></li>
<li><a href="CommunalNesting.htm"><font size="-1">Communal
nesting</font></a></li>
</ul>
</li>
<li><a href="WhatIsMyRatDoingFAQ.htm"><font size="-1">What is
my rat doing? FAQ</font></a></li>
<li><a href="Glossary.htm"><font size="-1">Glossary of rat
behavior terms</font></a></li>
<li><a href="norway_rat_vocalizations.htm"><font size="-1">Norway
rat vocalizations</font></a></li>
<li><a href="DiggingBox.htm"><font size="-1">Glass-sided
digging box</font></a></li>
<li><a href="RatsAndMazes.htm"><font size="-1">Rats and mazes</font></a>
<ul>
<li><a href="/maze"><font size="-1">Rat maze simulator</font></a></li>
<li><a href="PaperMaze.htm"><font size="-1">Paper and
pencil mazes</font></a></li>
</ul>
</li>
</ul>
</td>
<td valign="top">
<p><a href="RatSensoryWorldMain.htm"><b>The Rat's Sensory World</b></a></p>
<ul>
<li><font size="-1">Introduction: </font><a
href="perception.htm"><font size="-1">Journey into a rat's world</font></a>
<ul>
<li><font size="-1">Vision: </font><a href="RatVision.htm"><font
size="-1">What do rats see?</font></a></li>
<li><font size="-1">Touch: </font><a href="RatWhiskers.htm"><font
size="-1">The world through a rat's whiskers</font></a></li>
<li><font size="-1">Smell: </font><a
href="RatOlfaction.htm"><font size="-1">The rat's world of smell</font></a></li>
<li><font size="-1">Hearing: </font><a
href="rathearing.htm"><font size="-1">What do rats hear?</font></a></li>
<li><font size="-1">Taste: </font><a href="RatTaste.htm"><font
size="-1">Tasting Foods</font></a></li>
<li><a href="HearingWhiskers.htm"><font size="-1">Hearing
with whiskers</font></a></li>
</ul>
</li>
<li><a href="RatCam.htm"><font size="-1">Rat Cam</font></a><font
size="-1">: short movies through a rat's eyes</font></li>
<li><a href="BlackLight.htm"><font size="-1">Rats under a black
light</font></a></li>
</ul>
</td>
<td valign="top">
<p><a href="RatBiologyMain.htm"><b>Rat Biology</b></a></p>
<ul>
<li><font size="-1"><b>Rat Anatomy</b></font>
<ul>
<li><a href="RatTails.htm"><font size="-1">Rat tails</font></a>,
<a href="Teeth.htm"><font size="-1">Rat teeth</font></a>,
<a href="claws.htm"><font size="-1">Rat claws</font></a>,
<a href="Eyes.htm"><font size="-1">Rat eyes</font></a></li>
<li><a href="porphyrin.htm"><font size="-1">Those red
tears: porphyrin and the Norway rat</font></a></li>
<li><a href="testicles.htm"><font size="-1">Why are rat
testicles so big?</font></a></li>
<li><a href="vomit.htm"><font size="-1">Why rats can't vomit</font></a></li>
<li><a href="PawPreference.htm"><font size="-1">Are rats
right-handed?</font></a></li>
<li><a href="PubicSymphysis.htm"><font size="-1">The rat's
pubic symphysis</font></a></li>
<li><a href="DumboRatMutation.htm"><font size="-1">The
dumbo rat mutation and human analogues</font></a></li>
<li><a href="CollapsibleSkeleton.htm"><font size="-1">Do
rats have a collapsible skeleton?</font></a></li>
</ul>
</li>
<li><font size="-1"><b>Rat Coat Biology</b></font>
<ul>
<li><a href="CoatColorMutations.htm"><font size="-1">Where
do rat coat colors come from?</font></a></li>
<li><a href="CoatColor.htm"><font size="-1">Coat color,
temperament, and domestication</font></a><font size="-1"><br>
Also: </font><a href="ExperimentalCoatTempmt.htm"><font size="-1">coat
color and temperament in rats, deermice</font></a></li>
<li><a href="megacolon.htm"><font size="-1">White blazes
and megacolon</font></a></li>
<li><a href="AustralianBlue.htm"><font size="-1">Australian
blue rats: a hypothesis</font></a></li>
<li><a href="CoatTypes.htm"><font size="-1">Where do rat
coat types come from?</font></a><font size="-1"><br>
Also: </font><a href="hairless.htm"><font size="-1">hairless</font></a><font
size="-1"> mutation in mice and humans.</font></li>
<li><a href="AlbinoPigmented.htm"><font size="-1">How do
albino rats differ from pigmented rats?</font></a></li>
</ul>
</li>
<li><a href="Stats.htm"><font size="-1">Biological statistics
of the Norway rat</font></a></li>
<li><a href="PostPartumConception.htm"><font size="-1">How soon
can female rats conceive after giving birth?</font></a></li>
<li><a href="RigorMortis.htm"><font size="-1">Rat rigor mortis</font></a></li>
</ul>
</td>
</tr>
<tr>
<td valign="top">
<p><a href="RatSystematicsMain.htm"><b>Rat Systematics</b></a></p>
<ul>
<li><a href="RatSpecies.htm"><font size="-1">Rat species,
strains, breeds, and varieties</font></a></li>
<li><a href="Hybridization.htm"><font size="-1">Can Norway rats
and roof rats interbreed?</font></a>
<ul>
<li><a href="QuizNorwayRatRoofRat.htm"><font size="-1">Quiz:
Norway rat or roof rat?</font></a></li>
</ul>
</li>
<li><a href="RatsMice.htm"><font size="-1">Rats and mice:
what's the difference?</font></a>
<ul>
<li><a href="QuizRatOrMouse.htm"><font size="-1">Quiz: rat
or mouse?</font></a></li>
</ul>
</li>
<li><a href="RatMouseHybrid.htm"><font size="-1">Are rat-mouse
hybrids possible?</font></a></li>
<li><a href="pet_rodent_classification.htm"><font size="-1">Taxonomy
of rodent pets</font></a></li>
<li><a href="history.htm"><font size="-1">History of the Norway
rat</font></a></li>
</ul>
</td>
<td valign="top">
<p><a href="WildRatsMain.htm"><b>Wild Rats</b></a></p>
<ul>
<li><a href="WildRats.htm"><font size="-1">Wild rat behavior</font></a></li>
<li><a href="WildAndDomesticRats.htm"><font size="-1">Wild rats
in captivity, domestic rats in the wild</font></a></li>
<li><a href="WildRatDisease.htm"><font size="-1">Wild rats and
disease</font></a></li>
<li><a href="WildRatBites.htm"><font size="-1">Wild rat bites</font></a></li>
<li><a href="DryBite.htm"><font size="-1">Do rats have a dry
bite?</font></a></li>
<li><a href="MapWildNorwayRatsCalifornia.htm"><font size="-1">Map
of wild Norway rats in California</font></a></li>
</ul>
</td>
<td valign="top">
<p><a href="RatHealthNotes.htm"><b>Rat Health Notes</b></a></p>
<ul>
<li><a href="TumorSpaying.htm"><font size="-1">Tumors and
spaying</font></a></li>
<ul>
<li><small><a href="SpayTumorIncidencePetRat.html">Spaying
and post-spay tumor incidence in a pet rat population</a></small></li>
</ul>
<li><a href="Neutering.htm"><font size="-1">What does neutering
do?</font></a></li>
<li><a href="PregnancyAndMammaryTumors.htm"><font size="-1">Pregnancy
and mammary tumors</font></a></li>
<li><a href="PostPartumConception.htm"><font size="-1">How soon
can female rats conceive after giving birth?</font></a></li>
<li><a href="megacolon.htm"><font size="-1">White blazes and
megacolon</font></a></li>
<li><a href="AustralianBlue.htm"><font size="-1">Australian
blue rats: a hypothesis</font></a></li>
<li><a href="maleratweight.htm"><font size="-1">Male rat weight</font></a></li>
<li><a href="RatYears.htm"><font size="-1">How old is a rat in
human years?</font></a></li>
<li><a href="MartinsCages.htm"><font size="-1">Martin's cage
overview</font></a></li>
<li><a href="AmmoniaMyco.htm"><font size="-1">Dirty cages
aggravate mycoplasma</font></a><font size="-1"><br>
Also see </font><a href="Broderson1976.htm"><font size="-1">research
article</font></a></li>
<li><a href="RatBedding.htm"><font size="-1">Comparative
studies of different types of rat bedding</font></a></li>
</ul>
</td>
</tr>
</tbody>
</table>
</font></p>
<p><font size="-1">I've also written some fun stuff about rats --
illustrated stories, spoofs, rat artwork, and an interactive quiz.
Enjoy! </font> <br clear="all">
</p>
<p><a href="RatHumorMain.htm"><b>Rat Humor</b></a></p>
<ul>
<li><font size="-1"><b>Rat art</b></font>
<ul>
<li><a href="PawPaintingRats.htm"><font size="-1">Paw Painting by
Rats:</font></a><font size="-1"> Widget, Cricket and Snip display their
artistic skills with paw painting.<br>
Visit </font><a href="BehindScenes.htm"><font size="-1">Behind the
Scenes</font></a><font size="-1"> and </font><a
href="BehindScenes2.htm"><font size="-1">Tail Painting</font></a><font
size="-1"> and </font><a href="RatsOnCanvas.htm"><font size="-1">Rats
on Canvas</font></a><font size="-1"> to see the grand masters at work.</font></li>
</ul>
</li>
<li><font size="-1"><b>Interactive</b></font>
<ul>
<li><a href="QuizRatOrMouse.htm"><font size="-1">Quiz: rat or
mouse?</font></a></li>
<li><a href="QuizNorwayRatRoofRat.htm"><font size="-1">Quiz:
Norway rat or roof rat?</font></a></li>
<li><a href="/maze"><font size="-1">Rat Maze Simulator</font></a></li>
</ul>
</li>
<li><font size="-1"><b>Spoofs</b></font>
<ul>
<li><a href="petbrickfaq.htm"><font size="-1">Pet Brick FAQ</font></a></li>
<li><a href="laundry.htm"><font size="-1">Rat Laundry</font></a></li>
<li><a href="RatEnglishDictionary.htm"><font size="-1">Rat-English
Dictionary</font></a></li>
<li><a href="Courses.htm"><font size="-1">Courses from Rat
University</font></a></li>
<li><a href="Products.htm"><font size="-1">Rat products</font></a></li>
<li><a href="RealEstate.htm"><font size="-1">Rat Real Estate</font></a></li>
<li><a href="88lines44rats.htm"><font size="-1">88 Lines about 44
Rats</font></a></li>
<li><a href="MouseTale.htm"><font size="-1">The Mouse's Tale</font></a></li>
</ul>
</li>
<li><font size="-1"><b>Stories</b></font>
<ul>
<li><a href="EggRats.htm"><font size="-1">Rats and Eggshells</font></a></li>
<li><a href="PeasPeasPeas.htm"><font size="-1">Peas, peas peas</font></a></li>
<li><a href="Nutcracker.htm"><font size="-1">Nutcracker</font></a></li>
<li><a href="free_range.htm"><font size="-1">Free range time with
Widget, Cricket and Snip</font></a></li>
<li><a href="noodle.htm"><font size="-1">A Noodle Adventure</font></a></li>
<li><a href="Winter.htm"><font size="-1">On this winter morning</font></a></li>
<li><a href="Album01.html"><font size="-1">Rat photo album</font></a></li>
</ul>
</li>
</ul>
<p><a href="updates.htm"><font size="-1"><b>Updates:</b></font></a><font
size="-1">
<i>Last updated November 29, 2012.<br>
</i></font></p>
<p><i>
<hr></i><font size="-1"><i>Portions of this site have been translated
into other languages:</i></font></p>
<ul>
<li><a href="http://wildrats.narod.ru/" target="Article"><font
size="-1"><i>Russian</i></font></a></li>
</ul>
<center>
<hr>
<div class="navbar"> Home • <a href="RatBehaviorMain.htm">Rat
Behavior</a> • <a href="RatSensoryWorldMain.htm">The Rat's
Sensory World</a> • <a href="RatBiologyMain.htm">Rat Biology</a>
• <a href="RatSystematicsMain.htm">Rat Systematics</a> •
<a href="WildRatsMain.htm">Wild Rats</a> • <a href="RatHealthNotes.htm">Rat
Health Notes</a> • <a href="RatHumorMain.htm">Rat Humor</a>
• <a href="references.htm">References</a> • <a href="updates.htm">Updates</a>
• <a href="About.htm">About</a></div>
</center>
<p>
</p>
<hr noshade="noshade">
<p></p>
<center><span class="footer"> All photographs, graphics, text and
sounds on this website are Copyright © 2003, 2004. All
rights reserved.<br>
Please request permission if you wish to use any images or content on
this website<br>
Contact: x@y.org (where x = webmaster, y = ratbehavior)<br>
http://www.ratbehavior.org</span></center>
<p> </p>
<p></p>
</body>
</html>
|
Rat Behavior and Biology
ul {padding-left:16;margin-left:5}
| | |
| --- | --- |
| Home | |
| |
| |
| --- |
| |
**Rat Behavior and Biology**
***(Anne's rat
page)***
Welcome to my website about rats. I have written a number of
articles about rat behavior and
biology. These articles are based on my study of the scientific
literature available on rats and on my own observations of rat
behavior.
| | | |
| --- | --- | --- |
| [**Rat Behavior**](RatBehaviorMain.htm)* [Norway
rat behavior repertoire](norway_rat_ethogram.htm)
*Expanded articles:*
+ [Aggression](Aggression.htm)
+ [Rat play](RatPlay.htm)
+ [How do rats
choose what to eat?](FoodChoices.htm)
+ [Why do rats
pee everywhere?](WhyDoRatsPee.htm)
Also: [Urine marking](UrineMarking.htm)
+ [Infanticide](infanticide.htm)
+ [Communal
nesting](CommunalNesting.htm)
* [What is
my rat doing? FAQ](WhatIsMyRatDoingFAQ.htm)
* [Glossary of rat
behavior terms](Glossary.htm)
* [Norway
rat vocalizations](norway_rat_vocalizations.htm)
* [Glass-sided
digging box](DiggingBox.htm)
* [Rats and mazes](RatsAndMazes.htm)
+ [Rat maze simulator](/maze)
+ [Paper and
pencil mazes](PaperMaze.htm)
| [**The Rat's Sensory World**](RatSensoryWorldMain.htm)* Introduction: [Journey into a rat's world](perception.htm)
+ Vision: [What do rats see?](RatVision.htm)
+ Touch: [The world through a rat's whiskers](RatWhiskers.htm)
+ Smell: [The rat's world of smell](RatOlfaction.htm)
+ Hearing: [What do rats hear?](rathearing.htm)
+ Taste: [Tasting Foods](RatTaste.htm)
+ [Hearing
with whiskers](HearingWhiskers.htm)
* [Rat Cam](RatCam.htm): short movies through a rat's eyes
* [Rats under a black
light](BlackLight.htm)
| [**Rat Biology**](RatBiologyMain.htm)* **Rat Anatomy**
+ [Rat tails](RatTails.htm),
[Rat teeth](Teeth.htm),
[Rat claws](claws.htm),
[Rat eyes](Eyes.htm)
+ [Those red
tears: porphyrin and the Norway rat](porphyrin.htm)
+ [Why are rat
testicles so big?](testicles.htm)
+ [Why rats can't vomit](vomit.htm)
+ [Are rats
right-handed?](PawPreference.htm)
+ [The rat's
pubic symphysis](PubicSymphysis.htm)
+ [The
dumbo rat mutation and human analogues](DumboRatMutation.htm)
+ [Do
rats have a collapsible skeleton?](CollapsibleSkeleton.htm)
* **Rat Coat Biology**
+ [Where
do rat coat colors come from?](CoatColorMutations.htm)
+ [Coat color,
temperament, and domestication](CoatColor.htm)
Also: [coat
color and temperament in rats, deermice](ExperimentalCoatTempmt.htm)
+ [White blazes
and megacolon](megacolon.htm)
+ [Australian
blue rats: a hypothesis](AustralianBlue.htm)
+ [Where do rat
coat types come from?](CoatTypes.htm)
Also: [hairless](hairless.htm) mutation in mice and humans.
+ [How do
albino rats differ from pigmented rats?](AlbinoPigmented.htm)
* [Biological statistics
of the Norway rat](Stats.htm)
* [How soon
can female rats conceive after giving birth?](PostPartumConception.htm)
* [Rat rigor mortis](RigorMortis.htm)
|
| [**Rat Systematics**](RatSystematicsMain.htm)* [Rat species,
strains, breeds, and varieties](RatSpecies.htm)
* [Can Norway rats
and roof rats interbreed?](Hybridization.htm)
+ [Quiz:
Norway rat or roof rat?](QuizNorwayRatRoofRat.htm)
* [Rats and mice:
what's the difference?](RatsMice.htm)
+ [Quiz: rat
or mouse?](QuizRatOrMouse.htm)
* [Are rat-mouse
hybrids possible?](RatMouseHybrid.htm)
* [Taxonomy
of rodent pets](pet_rodent_classification.htm)
* [History of the Norway
rat](history.htm)
| [**Wild Rats**](WildRatsMain.htm)* [Wild rat behavior](WildRats.htm)
* [Wild rats
in captivity, domestic rats in the wild](WildAndDomesticRats.htm)
* [Wild rats and
disease](WildRatDisease.htm)
* [Wild rat bites](WildRatBites.htm)
* [Do rats have a dry
bite?](DryBite.htm)
* [Map
of wild Norway rats in California](MapWildNorwayRatsCalifornia.htm)
| [**Rat Health Notes**](RatHealthNotes.htm)* [Tumors and
spaying](TumorSpaying.htm)
+ [Spaying
and post-spay tumor incidence in a pet rat population](SpayTumorIncidencePetRat.html)
* [What does neutering
do?](Neutering.htm)
* [Pregnancy
and mammary tumors](PregnancyAndMammaryTumors.htm)
* [How soon
can female rats conceive after giving birth?](PostPartumConception.htm)
* [White blazes and
megacolon](megacolon.htm)
* [Australian
blue rats: a hypothesis](AustralianBlue.htm)
* [Male rat weight](maleratweight.htm)
* [How old is a rat in
human years?](RatYears.htm)
* [Martin's cage
overview](MartinsCages.htm)
* [Dirty cages
aggravate mycoplasma](AmmoniaMyco.htm)
Also see [research
article](Broderson1976.htm)
* [Comparative
studies of different types of rat bedding](RatBedding.htm)
|
I've also written some fun stuff about rats --
illustrated stories, spoofs, rat artwork, and an interactive quiz.
Enjoy!
[**Rat Humor**](RatHumorMain.htm)
* **Rat art**
+ [Paw Painting by
Rats:](PawPaintingRats.htm) Widget, Cricket and Snip display their
artistic skills with paw painting.
Visit [Behind the
Scenes](BehindScenes.htm) and [Tail Painting](BehindScenes2.htm) and [Rats
on Canvas](RatsOnCanvas.htm) to see the grand masters at work.
* **Interactive**
+ [Quiz: rat or
mouse?](QuizRatOrMouse.htm)
+ [Quiz:
Norway rat or roof rat?](QuizNorwayRatRoofRat.htm)
+ [Rat Maze Simulator](/maze)
* **Spoofs**
+ [Pet Brick FAQ](petbrickfaq.htm)
+ [Rat Laundry](laundry.htm)
+ [Rat-English
Dictionary](RatEnglishDictionary.htm)
+ [Courses from Rat
University](Courses.htm)
+ [Rat products](Products.htm)
+ [Rat Real Estate](RealEstate.htm)
+ [88 Lines about 44
Rats](88lines44rats.htm)
+ [The Mouse's Tale](MouseTale.htm)
* **Stories**
+ [Rats and Eggshells](EggRats.htm)
+ [Peas, peas peas](PeasPeasPeas.htm)
+ [Nutcracker](Nutcracker.htm)
+ [Free range time with
Widget, Cricket and Snip](free_range.htm)
+ [A Noodle Adventure](noodle.htm)
+ [On this winter morning](Winter.htm)
+ [Rat photo album](Album01.html)
[**Updates:**](updates.htm)
*Last updated November 29, 2012.*
*---**Portions of this site have been translated
into other languages:*
* [*Russian*](http://wildrats.narod.ru/)
---
Home • [Rat
Behavior](RatBehaviorMain.htm) • [The Rat's
Sensory World](RatSensoryWorldMain.htm) • [Rat Biology](RatBiologyMain.htm)
• [Rat Systematics](RatSystematicsMain.htm) •
[Wild Rats](WildRatsMain.htm) • [Rat
Health Notes](RatHealthNotes.htm) • [Rat Humor](RatHumorMain.htm)
• [References](references.htm) • [Updates](updates.htm)
• [About](About.htm)
---
All photographs, graphics, text and
sounds on this website are Copyright © 2003, 2004. All
rights reserved.
Please request permission if you wish to use any images or content on
this website
Contact: x@y.org (where x = webmaster, y = ratbehavior)
http://www.ratbehavior.org
| http://www.ratbehavior.org/ |
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<td align="left" valign="top" class="body_bold_80">Let rip!<br>
It's biblical!
</td>
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<td align="left" valign="top"><img src="../media/grid/spacer_10.gif" width="140" height="8"></td>
</tr>
<tr>
<td align="left" valign="top" class="body_70">Lost for a smart remark to see off your enemies? Unable to deliver that killer insult? Put an end to unscriptural restraint with the amazing Biblical Curse Generator, which is pre-loaded with blistering smackdowns as delivered by Elijah, Jeremiah and other monumentally angry saints.</td>
</tr>
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<td align="left" valign="top"> </td>
</tr>
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</tr>
<tr>
<td align="left" valign="top"><img src="media/biblical_curse_generator.gif" alt="biblical curse generator" width="450" height="165"></td>
</tr>
<tr>
<td align="left" valign="top"><img src="../media/grid/spacer_10.gif" width="450" height="20"></td>
</tr>
<tr>
<td align="left" valign="top" class="body_bold_90">To create the biblical imprecation of your dreams, simply click the button below, and smite your foes with a custom-made curse straight out of the Old Testament!</td>
</tr>
<tr>
<td align="left" valign="top"><img src="../media/grid/spacer_10.gif" width="450" height="20"></td>
</tr>
<tr>
<td align="center" valign="top"><INPUT TYPE="button" VALUE="Take that!" onClick="insult()"></td>
</tr>
<tr>
<td align="left" valign="top"><img src="../media/grid/spacer_10.gif" width="450" height="5"></td>
</tr>
<tr>
<td align="left" valign="top"><img src="media/flash_top.gif" alt="flash" width="450" height="58"></td>
</tr>
<tr>
<td align="center" valign="top"><textarea name="message" cols="50" rows="3" wrap="on"></textarea></td>
</tr>
<tr>
<td align="left" valign="top"><img src="media/flash_bottom.gif" alt="flash" width="450" height="58"></td>
</tr>
<tr>
<td align="left" valign="top"> </td>
</tr>
</table></FORM>
<!-- InstanceEndEditable --></td>
<td align="left" valign="top"> </td>
<td align="left" valign="top"><!-- InstanceBeginEditable name="rh_column" -->
<table width="140" border="0" cellspacing="0" cellpadding="0">
<tr>
<td align="left" valign="top"><img src="../media/grid/spacer_10.gif" width="140" height="5"></td>
</tr>
<tr>
<td align="left" valign="top"> </td>
</tr>
</table>
<!-- InstanceEndEditable --></td>
<td align="left" valign="top"> </td>
<td align="left" valign="top"><table width="120" border="0" cellspacing="0" cellpadding="0">
<tr>
<td align="left" valign="top" class="body_70"><img src="../media/grid/spacer_10.gif" width="120" height="5"></td>
</tr>
<tr>
<td align="left" valign="top" class="body_70"><a href="https://twitter.com/shipoffoolscom" target="_top"><img src="../media/ads_120_240/04.gif" alt="follow ship of fools on twitter" width="120" height="240" border="0"></a></td>
</tr>
<tr>
<td align="left" valign="top" class="body_70"><img src="../media/grid/spacer_10.gif" width="120" height="10"></td>
</tr>
<tr>
<td align="left" valign="top" class="body_70"><a href="../shop/postcards/index.html" target="_top"><img src="../media/ads_120_240/03.gif" alt="buy your ship of fools postcards" width="120" height="240" border="0"></a></td>
</tr>
<tr>
<td align="left" valign="top" class="body_70"><img src="../media/grid/spacer_10.gif" width="120" height="10"></td>
</tr>
<tr>
<td align="left" valign="top" class="body_70"><a href="../shop/mugs/index.html" target="_top"><img src="../media/ads_120_240/02.gif" alt="sip of fools mugs from your favourite nautical website" width="120" height="240" border="0"></a></td>
</tr>
</table></td>
<td align="left" valign="top"> </td>
</tr>
<tr>
<td colspan="9" align="left" valign="top"><img src="../media/grid/spacer_10.gif" width="960" height="30"></td>
</tr>
<tr>
<td align="left" valign="top"> </td>
<td align="left" valign="top"> </td>
<td align="left" valign="top"> </td>
<td align="left" valign="top"><img src="../media/logo/sof_plus_copyright.gif" width="100" height="74"></td>
<td align="left" valign="top"> </td>
<td align="left" valign="top"> </td>
<td align="left" valign="top"> </td>
<td align="left" valign="top"> </td>
<td align="left" valign="top"> </td>
</tr>
<tr>
<td colspan="9" align="left" valign="top"><img src="../media/grid/spacer_10.gif" width="960" height="20"></td>
</tr>
</table>
</td>
</tr>
</table>
</body>
<!-- InstanceEnd --></html>
|
Ship of Fools: Features
<!--
rnd.today=new Date();
rnd.seed=rnd.today.getTime();
mayYou = new Array(
"I pray thou shalt",
"I hope you will",
"Behold, thou shalt",
"May you",
"Thou shalt",
"O that thou wouldest");
haveBadThingsHappen = new Array(
"have more mother-in-laws than King Solomon",
"be pursued into the mountains by sex-mad baboons",
"be whipped with a thousand scorpions",
"be thrown into a den of hyperactive lions",
"be swallowed by a whale with excessively bad breath",
"be smitten with all-over boils",
"be mocked by eunuchs",
"be captured by Midianite maniacs",
"become as popular as a boil on the king's backside",
"be plagued with gnats, flies and locusts",
"be taunted by the king's concubines",
"fall under a speeding chariot",
"be as welcome as a fart in the queen's bedchamber",
"accidentally insult Goliath",
"go about weeping and wailing in sackcloth and ashes",
"go on a diet of crunchy, unsweetened locusts",
"be trampled by a herd of stampeding pigs",
"be cast onto a steaming dung-heap",
"be turned into a pillar of salt",
"see your pomegranates wither",
"beget difficult teenagers",
"be kicked by an incontinent camel",
"crash the king's best-loved chariot"
);
ohYou = new Array(
"thou",
"O thou",
"O ye"
);
ofLittleFaith = new Array(
"of little faith",
"whose name is but dung",
"who art a byword for idiocy",
"breaker of the commandments",
"discourager of the brethren",
"wolf in sheep's clothing",
"sad Pharisee",
"armpit of Satan",
"irritating inhabitant of Gath",
"child of Jezebel",
"son of thunder",
"relative of Herod",
"incompetent tax-collector",
"lazy Babylonian",
"babbling Assyrian",
"Amalekite dog",
"lying Girgashite",
"love-crazed Gittite",
"creature of the pit",
"bull of Bashan",
"Mesopotomian harlot",
"wayward winebibber",
"son of a Philistine",
"sulphurous nonentity",
"love-child of Methuselah",
"plaything of Beelzebub",
"dabbler in abominations",
"exceedingly foolish virgin",
"denizen of the underworld",
"offspring of a squashed cockroach"
);
hearThis = new Array(
"Listen",
"Hear this",
"Take heed",
"Woe unto thee",
"Harken"
);
function rnd() {
rnd.seed = (rnd.seed\*9301+49297) % 233280;
return rnd.seed/(233280.0);
};
function rand(number) {
return Math.ceil(rnd()\*number);
};
// end central randomizer. -->
function randomSelect( anArray )
{
rand1=rand(anArray.length)-1;
clause = anArray[rand1];
return clause;
}
function insult()
{
numberOfForms = 2;
formNumber = rand( numberOfForms );
if ( formNumber==1 )
{
msg = randomSelect( mayYou ) + " " +
randomSelect( haveBadThingsHappen ) + ", " +
randomSelect( ohYou ) + " " +
randomSelect( ofLittleFaith ) + "!";
}
else if ( formNumber==2 )
{
msg = randomSelect( hearThis ) + ", " +
randomSelect( ohYou ) + " " +
randomSelect( ofLittleFaith ) + ", for you will " +
randomSelect( haveBadThingsHappen) + "!";
}
document.insult\_form.message.value=msg;
}
<!--
a:link { color: #cc0000; text-decoration: none; }
a:visited { text-decoration: none; color: #cc0000; }
a:hover { text-decoration: underline; color: #005B82; }
a:active { text-decoration: none; color: #005B82; }
td#blacklink a:link { color: #000000; text-decoration: none; }
td#blacklink a:visited { text-decoration: none; color: #000000; }
td#blacklink a:hover { text-decoration: underline; color: #005B82; }
td#blacklink a:active { text-decoration: none; color: #005B82; }
-->
<!-- hide me
function openWin(URL) {
// Name the Window, so the remote can target it
self.name = "parent\_window";
aWindow=window.open(URL,"remote","height=300,width=450,scrollbars=no");
}
// stop hiding me -->
// old pop script (to go in body tag)
// onload="PopIt('','');"
| | | | | | | | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
|
| | |
| --- | --- |
| [homepage](../index.html) | |
| | [click here for gadget for god](http://shipoffools.com/gadgets/index.html) | |
| |
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| --- |
| |
| [about the ship](../shipstuff/index.html) | | [sign up for our newsletter](../organ/index.html) | |
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| | [community](https://forums.shipoffools.com) | | [the mystery worshipper](../mystery/index.html) | | [gadgets for god](../gadgets/index.html) | | [caption competition](/cgi-bin/caption.pl) | | [foolishness](../foolishness/index.html) | | [features](../features/index.html) | | [ship stuff](../shipstuff/index.html) | |
|
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| | [born twice](../borntwice/index.html) | | [signs and blunders](../signs/index.html) | |
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| --- | --- | --- | --- | --- | --- | --- | --- | --- |
| | | | | | | | | |
| |
| |
| --- |
| |
| Let rip!
It's biblical!
|
| |
| Lost for a smart remark to see off your enemies? Unable to deliver that killer insult? Put an end to unscriptural restraint with the amazing Biblical Curse Generator, which is pre-loaded with blistering smackdowns as delivered by Elijah, Jeremiah and other monumentally angry saints. |
| |
| |
| |
| --- |
| |
| biblical curse generator |
| |
| To create the biblical imprecation of your dreams, simply click the button below, and smite your foes with a custom-made curse straight out of the Old Testament! |
| |
| |
| |
| flash |
| |
| flash |
| |
| |
| |
| --- |
| |
| |
| |
| |
| --- |
| |
| [follow ship of fools on twitter](https://twitter.com/shipoffoolscom) |
| |
| [buy your ship of fools postcards](../shop/postcards/index.html) |
| |
| [sip of fools mugs from your favourite nautical website](../shop/mugs/index.html) |
| |
| |
| | | | | | | | | |
| |
|
| http://www.ship-of-fools.com/curse/index.html |
<html>
<head>
<title>Jeff's Virtual Cyclone Cellar</title>
</head>
<body bgcolor="#710502" text="#FFEC6A" link="#FFFFFF" vlink="#888888">
<CENTER><IMG SRC="/images/cover05.jpg"></CENTER>
<a href="http://chaserconvention.com">
<center>
<a href="http://chaserconvention.com"><img src="http://chaserconvention.com/images/chasercon468x60.jpg" width="468" height="60" border="0"></a>
</center>
<HR>
<p>
<center>
<font size="+2" face="Trebuchet MS"><B> Thank you for taking shelter in Jeff's Virtual Cyclone Cellar. While waiting for the all-clear siren to sound, feel free to take a look at some pictures and stories of the storm chasing adventures of the late Jeff Wear....</B></font>
</center>
<p>
<hr>
<p>
<center>
<p><img src="jeffmemorialsml.jpg" width="800" height="621"></p>
<p> </p>
<p align="justify"> On Monday morning, July 11, 2005 at 9 a.m., Jeff 's parents Marilyn and Bob Wear were notified at their front door that Jeff had been fatally injured in a traffic accident. Jeff, age 27 was their oldest son. He has a younger brother Matt, who lives in Los Angeles, California. The tragedy was very unexpected and hit the whole family very hard. It is widely known throughout the stormchasing community how important the weather was to Jeff. He had devoted his life to weather and that is why he moved to Norman, OK. <br>
<br>
Jeff was returning from chasing Hurricane Dennis the weekend of July 9-11, 2005, when he encountered sudden heavy rains on I-20 near Kilgore, Texas. Although he was driving at or below speed limit, the sudden downpour of water on the highway caused his car to hydroplane off the road, across the meridian and into oncoming traffic on the other side, where he was struck by a flatbed truck and killed instantly.</p>
<p align="justify">Jeff's family has decided that Jeff would have wanted to keep his work in storm chasing available for the pleasure of all that were interested, and as such his website will remain intact. His videos are still available through his mother Marilyn Wear as well directly through this website. We have made every effort to keep his website as close to the way he last left it as possible. We have linked a few pages he had completed but not yet linked to the main site. The payment links for video have been adjusted to go to his mother, and the email addresses have been changed as necessary. Otherwise, it's just like he left it. </p>
<p align="justify"><strong><img src="inmemoryofjefficon.jpg" width="96" height="100" border="2"></strong></p>
<p align="justify"><strong>You can read just how his fellow storm chasers felt about Jeff in this message board thread at <a href="http://www.stormtrack.org/forum/viewtopic.php?t=7391" target="_blank"><a href="http://www.stormtrack.org/jeffwear/">StormTrack.org</a>.</strong></p>
<p align="justify"><strong> </strong></p>
</center>
<p align="center">
<p>
<HR>
<p>
<p><FONT SIZE="+2">
<p>
</font>
<li><FONT SIZE="+2"><B><A HREF="/accounts/sum.htm">Chase Accounts</a></B> - A collection of accounts detailing storm chase events from 1996-present. </font><B><I>UPDATED THRU 06/13/05 </I></B>
<font size="+2">
<p>
</font><li><font size="+2"><B><A HREF="/movies/videos.htm">Videos</a></B> - Quicktime movie clips of tornadoes, lightning, and time lapse of supercells.</font> <blink><B><I>NEW!!!!</I></B></blink><br>
<br>
<li><font size="+2"><a href="accounts/2005/trip0502/index.htm"><strong>Colorado/California Vacation Trip</strong></a> - Tip accounting and photos from Jeff's trip</font><br>
<font size="+2">
</font>
<font size="+2"><li><B><A HREF="/images/pix.htm">Images</a></B> - Scanned 35mm prints and video captures of thunderstorm-related phenomena dating to 1994.
<p>
<li><B><A HREF="/store/store.htm">Merchandise</a></B> - DVD and VHS highlights from Jeff's chases.
<p>
<li><B><A HREF="/links/links.htm">Links</a></B> - Weather information, weather-related businesses, other chasers and severe weather enthusiasts.
<p>
<li><B><A HREF="/links/vault.htm">The Vault</a></B> - Chase humor, editorials, climate summaries, interesting weather events, and everything else that doesn't quite fit in the other categories.
<p>
</font><li><font size="+2"><B><A HREF="/bio/bio.htm">About Jeff</a></B> - If it weren't for that bathtub drain.....
</font>
<p>
<HR>
<P>
<B><I>Important <A HREF="disclaim.htm">disclaimer</a> regarding Jeff's Virtual Cyclone Cellar</I></B>
<p>
<hr>
<p>
<font face="Verdana"><B>
<CENTER>|Home|<A HREF="/bio/bio.htm">Biography</a>|<A HREF="/images/pix.htm">Pictures</a>|<A HREF="/accounts/sum.htm">Summaries</a>|<A HREF="/links/links.htm">Links</a>|<A HREF="mailto:MarilynWear@aol.com">E-mail</a>|</CENTER></B></font>
<p>
<center>
<A HREF="http://www.drylinehosting.com"><img src="http://drylinehosting.com/images/linkbanners/DH3_468x60.jpg" width="468" height="60"></a><br>
</center>
<p>
<center>
<A HREF="http://home.earthlink.net/~mwear240/marilynsstudio2.html"><IMG border=0 SRC="/images/paintingstudiosmall.jpg"></a></center>
<p>
<center>
<B>Looking for paintings of flowers, birds, or the Sierra Nevada landscape? Visit my mom's site <A HREF="http://home.earthlink.net/~mwear240/marilynsstudio2.html">Marilyn's Painting Studio</a>.</B>
</center>
<p>
<font size="2" face="Arial, Helvetica, sans-serif"><B>
This page was last updated 01-11-07 at 2055 CDT (by webhost, <a href="http://drylinehosting.com">Dryline Hosting</a>) </B></font>
</body>
</html> |
Jeff's Virtual Cyclone Cellar
![](/images/cover05.jpg)
[[![](http://chaserconvention.com/images/chasercon468x60.jpg)](http://chaserconvention.com)
---
**Thank you for taking shelter in Jeff's Virtual Cyclone Cellar. While waiting for the all-clear siren to sound, feel free to take a look at some pictures and stories of the storm chasing adventures of the late Jeff Wear....**
---
![](jeffmemorialsml.jpg)
On Monday morning, July 11, 2005 at 9 a.m., Jeff 's parents Marilyn and Bob Wear were notified at their front door that Jeff had been fatally injured in a traffic accident. Jeff, age 27 was their oldest son. He has a younger brother Matt, who lives in Los Angeles, California. The tragedy was very unexpected and hit the whole family very hard. It is widely known throughout the stormchasing community how important the weather was to Jeff. He had devoted his life to weather and that is why he moved to Norman, OK.
Jeff was returning from chasing Hurricane Dennis the weekend of July 9-11, 2005, when he encountered sudden heavy rains on I-20 near Kilgore, Texas. Although he was driving at or below speed limit, the sudden downpour of water on the highway caused his car to hydroplane off the road, across the meridian and into oncoming traffic on the other side, where he was struck by a flatbed truck and killed instantly.
Jeff's family has decided that Jeff would have wanted to keep his work in storm chasing available for the pleasure of all that were interested, and as such his website will remain intact. His videos are still available through his mother Marilyn Wear as well directly through this website. We have made every effort to keep his website as close to the way he last left it as possible. We have linked a few pages he had completed but not yet linked to the main site. The payment links for video have been adjusted to go to his mother, and the email addresses have been changed as necessary. Otherwise, it's just like he left it.
**![](inmemoryofjefficon.jpg)**
**You can read just how his fellow storm chasers felt about Jeff in this message board thread at [[StormTrack.org](http://www.stormtrack.org/jeffwear/).](http://www.stormtrack.org/forum/viewtopic.php?t=7391)**
---
- **[Chase Accounts](/accounts/sum.htm)** - A collection of accounts detailing storm chase events from 1996-present. ***UPDATED THRU 06/13/05***
- **[Videos](/movies/videos.htm)** - Quicktime movie clips of tornadoes, lightning, and time lapse of supercells. ***NEW!!!!***
- [**Colorado/California Vacation Trip**](accounts/2005/trip0502/index.htm) - Tip accounting and photos from Jeff's trip
- **[Images](/images/pix.htm)** - Scanned 35mm prints and video captures of thunderstorm-related phenomena dating to 1994.
- **[Merchandise](/store/store.htm)** - DVD and VHS highlights from Jeff's chases.
- **[Links](/links/links.htm)** - Weather information, weather-related businesses, other chasers and severe weather enthusiasts.
- **[The Vault](/links/vault.htm)** - Chase humor, editorials, climate summaries, interesting weather events, and everything else that doesn't quite fit in the other categories.
- **[About Jeff](/bio/bio.htm)** - If it weren't for that bathtub drain.....
---
***Important [disclaimer](disclaim.htm) regarding Jeff's Virtual Cyclone Cellar***
---
**|Home|[Biography](/bio/bio.htm)|[Pictures](/images/pix.htm)|[Summaries](/accounts/sum.htm)|[Links](/links/links.htm)|[E-mail](mailto:MarilynWear@aol.com)|**
[![](http://drylinehosting.com/images/linkbanners/DH3_468x60.jpg)](http://www.drylinehosting.com)
[![](/images/paintingstudiosmall.jpg)](http://home.earthlink.net/~mwear240/marilynsstudio2.html)
**Looking for paintings of flowers, birds, or the Sierra Nevada landscape? Visit my mom's site [Marilyn's Painting Studio](http://home.earthlink.net/~mwear240/marilynsstudio2.html).**
**This page was last updated 01-11-07 at 2055 CDT (by webhost, [Dryline Hosting](http://drylinehosting.com))**](http://chaserconvention.com)
| http://www.theperksofchasing.com/ |
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<h1><i> do it yourself information all trades</i></h1>
<p><b>The source of unbiased do it yourself information for diy'ers and householders - up to date diy information for around the home, 24 hours a day, 365 days of the year. We aim to give fast download times so you can find the page to answer your diy queries quickly, so we have kept the site simple and uncluttered. </b></p>
<p><b>We have sections on decorating, carpentry, electrics, general building and much, much more - just use the buttons to the right to take you to the various topics or use the buttons below on the right for the support pages. </b></p>
<p><b>Check out our <i><a href="directory/diy-suppliers.php" title="diydata directory of DIY suppliers of tools and other materials" >directory of DIY suppliers</a></i> to find national suppliers of all sorts of DIY products; we hope you find this directory helpful, all feedback is always welcome. </b></p>
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# *do it yourself information all trades*
**The source of unbiased do it yourself information for diy'ers and householders - up to date diy information for around the home, 24 hours a day, 365 days of the year. We aim to give fast download times so you can find the page to answer your diy queries quickly, so we have kept the site simple and uncluttered.**
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**Check out our *[directory of DIY suppliers](directory/diy-suppliers.php "diydata directory of DIY suppliers of tools and other materials")* to find national suppliers of all sorts of DIY products; we hope you find this directory helpful, all feedback is always welcome.**
**If you are not sure which area will cover what you want, just use the search facility above to search by keywords.**
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<center><font size="+4" color="#ff0000" face="impact, arial, 'times new roman'">Paul Burgess</font></center>
<p><center><font face="verdana, arial, helvetica, 'times new roman'">Burgess as in Burgess batteries,
<br>Burgess Meredith, A Clockwork Orange...
<br>Welcome to my world!</font></center>
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<br><a href="about.html">about me</a>
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<br><a href="srule.html">slide rules</a>
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<p><a href="http://pmburgess.blogspot.com">blog</a>
<p><a href="https://web.archive.org/web/20131116030237/http://books.dreambook.com/pburgess/guest.html">guestbook</a>
<p><a href="mailto:paul@paulburgess.org?subject=Your Site">e-mail</a>
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<p><font size="-1">In mountainous northeasternmost Iowa</font>
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<font size="+1" color="#ff0000">writings</font>
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singleness may not be the worst fate of all, as witness this <strike>conversation</strike> monologue overheard in a tavern
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a skeleton named skeptre is draining the world of its colors, one by one... while janos labors to build mankind's last hope, a statue of clay
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you befriended a creature from beyond. now you live in a darkened basement, while the world fears and loathes what you have become
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from a dream journal i've kept for years. little robot horses. life in a post-apocalyptic refugee camp. a throwback to the age of mammals. and much more
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they roam the galaxy, seeking to corrupt innocent alien races. they are professional serpents in eden. like lucifer himself, they are bearing light
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jilted and mocked, college biology major cal miller carries out the ultimate act of bioterrorism
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<a href="bolivar0.html">beneath the wheeling metal stars of night</a>
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the world revolution has come. "new justice" reigns on earth. imagine a boot stamping on a human face— forever
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in thirteen hundred ninety-two, meng ling-ch'u sailed the ocean blue. an alternate history of america
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for centuries they have been hated, feared, and conscripted as a human air corps. now the wingmen are coming back home to the caucasus
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the year is 2043. the place is mars. the event is the constitutional convention of the first independent human colony on the red planet
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fractured poetry, and more. "your triumph in life will be to live above tom's auto upholstery"...
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<a href="thaddeus.html">kata thaddaion</a>
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the gospel of thaddaeus. a second-century apocryphal gospel, complete with scholarly notes
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<a href="msc.html">mna sipri cilama</a>
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in my teens i suffered a radioactive core meltdown of the imagination. i created my own language, and then i wrote a book in it
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<br><font size="+1" color="#ff0000">zeros & ones</font>
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<a href="jetan.html">barsoomian chess</a>
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the game from edgar rice burroughs' novel <i>the chessmen of mars</i> lives, as a 1980's style computer game. source code included <b>[.zip]</b>
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<a href="weird.html">world wide weird</a>
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just some bizarre flotsam and jetsam i beachcombed while surfing the net
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<a href="opera.html">opera browser</a>
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why stay enslaved to bill gate$ and micro$oft internet explorer? here's opera, the fastest browser on earth
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<a href="browser.html">browser screenshots</a>
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what in the world is any sane person doing with <i><strike>eight</strike> <strike>nine</strike> ten</i> browsers on his computer?
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<a href="linux.html">escape to linux</a>
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<font face="verdana, arial, helvetica, 'times new roman'" size="1">
the story of how i made my exodus to linux— out of the land of micro$oft, out of the house of bondage
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<a href="lbrowser.html">browsers for linux</a>
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<font face="verdana, arial, helvetica, 'times new roman'" size="1">
and here are screenshots of the eight browsers i use under linux— which brings us to <i>eighteen</i> browsers in all
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<a href="wg.html">where's george?</a>
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use your computer to track where your money goes. one dollar bill i spent ended up in las vegas
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<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="msc25.mp3">mna sipri cilama (audio)</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
you can hear how that language i created sounds. here i am, reading chapter 25 of <i>mna sipri cilama</i> <b>[.mp3]</b>
</font>
</td>
</tr>
</table>
<br>
<br><font size="+1" color="#ff0000">pseudo-philosophical ramblings</font>
<table width="100%" border="0" cellspacing="2" cellpadding="6">
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<font color="#ff0000">></font><a href="sdsclm.html">standard disclaimer</a><font color="#ff0000"><</font>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
think for yourself, and "let the finder beware!"
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="zen.html">zen & the art of motorcycle maintenance</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
why it's a good thing i didn't read robert pirsig's excellent book until i was past forty
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="know.html">how do we know what we know?</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
sketched out as "an integral part of a rather densely thought-out view of language, history, human existence, trinitarian theology, and the kitchen sink"
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="abyss.html">recèsse de l'abîme</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
the logical structure of intentionality. self-consciousness as an infinite regress of self-representation and self-interpretation. just light conversational topics over dinner!
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="cloud.html">cloud of unknowing</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
musings on my "latter turning" toward mysticism. the human being as an embodied sign, or microcosm, of subtle macrocosmic invariants
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="wool.html">an argument from woolgathering</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
what is really going on inside of us when we engage in meditation? low-focus thinking and affective linking: those vague thoughts which drift like wisps of colored tissue paper across the back of your mind
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="mystic.html">mysticism--opiate or caffeine?</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
more on what's going on inside of us in meditation, and whether it deepens or dulls our awareness of the world around us
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="type.html">semiotics vs typology</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
the notion of signs and symbols in the history of christian theology. how we might draw on these historical resources to restore an intellectually rigorous "right-brain" counter-balance to "left-brain" modernity
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="goethe.html">goethe's way of science</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
what goethe was up to, seeking for the <i>urphänomen</i> "in, with, and under" individual phenomena. how this approach might be adapted to help heal the cartesian splits of modern culture
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="cycle.html">spengler & toynbee</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
historical cycles, and the current unfashionability of broad-gauge philosophies of history
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="kerouac.html">jack kerouac</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
the beat generation's most gifted writer, inspired by jazz, was up to something downright noneuclidean with language in his writings
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="sf.html">philosophy is not science fiction</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
i browse a collection of letters between a philosopher and a novelist who are discussing the semiotic of charles sanders peirce. this leads me off on some pretty bizarre tangents. oh well!
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="blue.html">why is the sky blue?</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
why science can explain why the sky is blue, but not why blue is blue. by the way, why are there so many more bookstores in today's illiterate world?
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="grass.html">every blade of grass has its own angel</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
my fractured take on god and evolution. and language and referentiality. and (of course) signs and symbols. and even paradigms
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="bateson.html">batesonian flapdoodle</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
how gregory bateson has been a pervasive bad influence on me. with an irreverent side excursion: "so what's up with this 'quest for the historical jesus'?"
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="ll3.html">coleridge, imagination, and slide rules</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
a meditation on a slide rule leads to cosmic thoughts about numbers. modern culture enjoins us to steer clear of such "deep" thoughts about the way things really are. but what if we will not submit?
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="knot.html">gordian knots of the soul</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
the manifold and tangled ways we engage in self-deception. how these ways relate to the liabilities of modern thought
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="mill.html">i see windmills by the sands of the seashore</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
you can take the boy out of the sixties, but you can't take the sixties out of the boy! with a concluding vision of the year 2040
</font>
</td>
</tr>
</table>
<br>
<br><font size="+1" color="#ff0000">sesqui-technical</font>
<table width="100%" border="0" cellspacing="2" cellpadding="6">
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="utopia.html">little utopias run amuck</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
minor league utopianism may shed more light on utopianism-in-the-large than many want light to see by
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="percy.html">walker percy</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
the semiotic of charles sanders peirce and the problem of the faith community in the writings of walker percy
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="triadic.html">why triadic?</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
challenges to the structure of peirce's semiotic. is the logical structure of a sign threefold, or fourfold, or twofold?
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="flux.html">glory met in unspeakable flux</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
the semiotics of religious experience, in the general theory of signs of charles morris, the semiotic of charles sanders peirce, and the philosophy of symbolic forms of ernst cassirer
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="time.html">god & time</a>
</font>
</td>
<td align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
does god dwell within time? or outside of time? or does the structure of temporal semiosis point us toward a view of god and time which is <nobr>both/and</nobr> and <nobr>neither/nor?</nobr>
</font>
</td>
</tr>
<tr>
<td width="42%" align="left" valign="top" bgcolor="#ffe480">
<font face="verdana, arial, helvetica, 'times new roman'" size="3">
<a href="richard.html">richard of st victor</a>
</font>
</td>
<td align="left" valign="top">
<font face="verdana, arial, helvetica, 'times new roman'" size="1">
one mediaeval theologian's nigh structuralist take on the trinity. abstract to the max
</font>
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</tr>
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Paul Burgess
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| Paul Burgess
Burgess as in Burgess batteries,
Burgess Meredith, A Clockwork Orange...
Welcome to my world!
| | |
| --- | --- |
|
[about me](about.html)
[churches](church.html)
[books](book.html)
[slide rules](srule.html)
[shortwave](sw.html)
[games](game.html)
[japanese robot cartoons](anime.html)
[beat generation](beat.html)
[hermetic](vanant.html)
[computers](pc.html)
[signs & symbols](sign.html)
[links](link.html)
[photo album](photo.html)
[blog](http://pmburgess.blogspot.com)
[guestbook](https://web.archive.org/web/20131116030237/http://books.dreambook.com/pburgess/guest.html)
[e-mail](mailto:paul@paulburgess.org?subject=Your Site)
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|
Paul Burgess
In mountainous northeasternmost Iowa
|
---
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|
writings
| | |
| --- | --- |
|
[overheard at tony frank's](tfrank.html)
|
singleness may not be the worst fate of all, as witness this conversation monologue overheard in a tavern
|
|
[the golem](golem.html)
|
a skeleton named skeptre is draining the world of its colors, one by one... while janos labors to build mankind's last hope, a statue of clay
|
|
[yellowstripes](yellow.html)
|
you befriended a creature from beyond. now you live in a darkened basement, while the world fears and loathes what you have become
|
|
[book of dreams](dream.html)
|
from a dream journal i've kept for years. little robot horses. life in a post-apocalyptic refugee camp. a throwback to the age of mammals. and much more
|
|
[bearing light](light0.html)
|
they roam the galaxy, seeking to corrupt innocent alien races. they are professional serpents in eden. like lucifer himself, they are bearing light
|
|
[and usher in these latter days](usher.html)
|
jilted and mocked, college biology major cal miller carries out the ultimate act of bioterrorism
|
|
[beneath the wheeling metal stars of night](bolivar0.html)
|
the world revolution has come. "new justice" reigns on earth. imagine a boot stamping on a human face— forever
|
|
[chinese columbus](colon.html)
|
in thirteen hundred ninety-two, meng ling-ch'u sailed the ocean blue. an alternate history of america
|
|
[wingmen](wingmen.html)
|
for centuries they have been hated, feared, and conscripted as a human air corps. now the wingmen are coming back home to the caucasus
|
|
[mars colony](mars.html)
|
the year is 2043. the place is mars. the event is the constitutional convention of the first independent human colony on the red planet
|
|
[vermilion lake](lake.html)
|
fractured poetry, and more. "your triumph in life will be to live above tom's auto upholstery"...
|
|
[kata thaddaion](thaddeus.html)
|
the gospel of thaddaeus. a second-century apocryphal gospel, complete with scholarly notes
|
|
[mna sipri cilama](msc.html)
|
in my teens i suffered a radioactive core meltdown of the imagination. i created my own language, and then i wrote a book in it
|
zeros & ones
| | |
| --- | --- |
|
[barsoomian chess](jetan.html)
|
the game from edgar rice burroughs' novel *the chessmen of mars* lives, as a 1980's style computer game. source code included **[.zip]**
|
|
[world wide weird](weird.html)
|
just some bizarre flotsam and jetsam i beachcombed while surfing the net
|
|
[opera browser](opera.html)
|
why stay enslaved to bill gate$ and micro$oft internet explorer? here's opera, the fastest browser on earth
|
|
[browser screenshots](browser.html)
|
what in the world is any sane person doing with *eight nine ten* browsers on his computer?
|
|
[escape to linux](linux.html)
|
the story of how i made my exodus to linux— out of the land of micro$oft, out of the house of bondage
|
|
[browsers for linux](lbrowser.html)
|
and here are screenshots of the eight browsers i use under linux— which brings us to *eighteen* browsers in all
|
|
[where's george?](wg.html)
|
use your computer to track where your money goes. one dollar bill i spent ended up in las vegas
|
|
[mna sipri cilama (audio)](msc25.mp3)
|
you can hear how that language i created sounds. here i am, reading chapter 25 of *mna sipri cilama* **[.mp3]**
|
pseudo-philosophical ramblings
| | |
| --- | --- |
|
>[standard disclaimer](sdsclm.html)<
|
think for yourself, and "let the finder beware!"
|
|
[zen & the art of motorcycle maintenance](zen.html)
|
why it's a good thing i didn't read robert pirsig's excellent book until i was past forty
|
|
[how do we know what we know?](know.html)
|
sketched out as "an integral part of a rather densely thought-out view of language, history, human existence, trinitarian theology, and the kitchen sink"
|
|
[recèsse de l'abîme](abyss.html)
|
the logical structure of intentionality. self-consciousness as an infinite regress of self-representation and self-interpretation. just light conversational topics over dinner!
|
|
[cloud of unknowing](cloud.html)
|
musings on my "latter turning" toward mysticism. the human being as an embodied sign, or microcosm, of subtle macrocosmic invariants
|
|
[an argument from woolgathering](wool.html)
|
what is really going on inside of us when we engage in meditation? low-focus thinking and affective linking: those vague thoughts which drift like wisps of colored tissue paper across the back of your mind
|
|
[mysticism--opiate or caffeine?](mystic.html)
|
more on what's going on inside of us in meditation, and whether it deepens or dulls our awareness of the world around us
|
|
[semiotics vs typology](type.html)
|
the notion of signs and symbols in the history of christian theology. how we might draw on these historical resources to restore an intellectually rigorous "right-brain" counter-balance to "left-brain" modernity
|
|
[goethe's way of science](goethe.html)
|
what goethe was up to, seeking for the *urphänomen* "in, with, and under" individual phenomena. how this approach might be adapted to help heal the cartesian splits of modern culture
|
|
[spengler & toynbee](cycle.html)
|
historical cycles, and the current unfashionability of broad-gauge philosophies of history
|
|
[jack kerouac](kerouac.html)
|
the beat generation's most gifted writer, inspired by jazz, was up to something downright noneuclidean with language in his writings
|
|
[philosophy is not science fiction](sf.html)
|
i browse a collection of letters between a philosopher and a novelist who are discussing the semiotic of charles sanders peirce. this leads me off on some pretty bizarre tangents. oh well!
|
|
[why is the sky blue?](blue.html)
|
why science can explain why the sky is blue, but not why blue is blue. by the way, why are there so many more bookstores in today's illiterate world?
|
|
[every blade of grass has its own angel](grass.html)
|
my fractured take on god and evolution. and language and referentiality. and (of course) signs and symbols. and even paradigms
|
|
[batesonian flapdoodle](bateson.html)
|
how gregory bateson has been a pervasive bad influence on me. with an irreverent side excursion: "so what's up with this 'quest for the historical jesus'?"
|
|
[coleridge, imagination, and slide rules](ll3.html)
|
a meditation on a slide rule leads to cosmic thoughts about numbers. modern culture enjoins us to steer clear of such "deep" thoughts about the way things really are. but what if we will not submit?
|
|
[gordian knots of the soul](knot.html)
|
the manifold and tangled ways we engage in self-deception. how these ways relate to the liabilities of modern thought
|
|
[i see windmills by the sands of the seashore](mill.html)
|
you can take the boy out of the sixties, but you can't take the sixties out of the boy! with a concluding vision of the year 2040
|
sesqui-technical
| | |
| --- | --- |
|
[little utopias run amuck](utopia.html)
|
minor league utopianism may shed more light on utopianism-in-the-large than many want light to see by
|
|
[walker percy](percy.html)
|
the semiotic of charles sanders peirce and the problem of the faith community in the writings of walker percy
|
|
[why triadic?](triadic.html)
|
challenges to the structure of peirce's semiotic. is the logical structure of a sign threefold, or fourfold, or twofold?
|
|
[glory met in unspeakable flux](flux.html)
|
the semiotics of religious experience, in the general theory of signs of charles morris, the semiotic of charles sanders peirce, and the philosophy of symbolic forms of ernst cassirer
|
|
[god & time](time.html)
|
does god dwell within time? or outside of time? or does the structure of temporal semiosis point us toward a view of god and time which is both/and and neither/nor?
|
|
[richard of st victor](richard.html)
|
one mediaeval theologian's nigh structuralist take on the trinity. abstract to the max
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<font size="6" color="#ffffff"><b>Big Ball of Mud</b></font><font></font></td>
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<p align="CENTER">
<font size="5"> <b> <A HREF="../index.html">Brian Foote</A>
and <A HREF="http://www.joeyoder.com/">Joseph Yoder</A>
</b></font>
</p>
<p align="CENTER">
<font size=3> <A HREF="http://www.cs.uiuc.edu">Department
of Computer Science</a><BR> <A HREF="http://www.uiuc.edu">University
of Illinois at Urbana-Champaign</A><BR> 1304 W. Springfield<BR>
<a href="../audio/cow02.wav">Urbana</A>, IL 61801 USA
</font>
<p align="CENTER">
<font size=2><i> <A HREF="mailto:foote@cs.uiuc.edu">foote@cs.uiuc.edu</a>
</i> (217) 328-3523<BR> <i><A HREF="mailto:yoder@cs.uiuc.edu">yoder@cs.uiuc.edu</a></i>
(217) 244-4695 </font>
</p>
<p align="CENTER">
<I>Saturday, June 26, 1999</I><BR>
<CENTER>
<font size=2> Fourth Conference on Patterns Languages of
Programs (<a href="http://st-www.cs.uiuc.edu/~hanmer/PLoP-97/">PLoP
'97</a>/<a href="http://www.cs.wustl.edu/~schmidt/EuroPLoP-97.html">EuroPLoP
'97</a>)<BR /> Monticello, Illinois, <a
href="http://www.laputan.com/cgi-bin/calendar?9+1997">September
1997</a><BR /> Technical Report #WUCS-97-34 (<a
href="http://st-www.cs.uiuc.edu/~hanmer/PLoP-97/Workshops.html">PLoP
'97</a>/<a
href="http://www.cs.wustl.edu/~schmidt/europlop-97/workshops.html">EuroPLoP
'97</a>), <a href="http://www.laputan.com/cgi-bin/calendar?9+1997">September
1997</a><br> <a href="http://www.cs.wustl.edu/">Department of
Computer Science</a>, <a href="http://www.wustl.edu">Washington
University</a><BR> <I>Chapter 29</I><BR /> <a
href="http://www.amazon.com/exec/obidos/ASIN/0201433044/qid%3D957230098/002-5670898-4593817">Pattern
Languages of Program Design 4</a><BR> edited by Neil Harrison, <a
href="../index.html">Brian Foote</a>, and Hans Rohnert<BR /> <a
href="http://www.awl.com">Addison-Wesley</a>, <a
href="http://www.laputan.com/cgi-bin/calendar?2000">2000</a> <br />
This volume is part of the <a
href="http://cseng.aw.com/seriesdetail.qry?SeriesID=34">Addison-Wesley
Software Patterns Series</a>.<BR />
</font>
</CENTER>
<p align="CENTER">
<font size=2> <I>This paper is also available in the
following formats:</I><BR> [<a href="/pub/foote/mud.pdf">PDF</a>] [<a
href="/pub/foote/mud.doc">Word</a>] [<a href="/pub/foote/mud.rtf">RTF</a>]
[<a href="/pub/foote/mud.ps">PostScript</a>]
</font>
</p>
<p align="CENTER">
<font size=2> Also by <B> <A HREF="../index.html">Brian
Foote</A>
</B> and <B> <A HREF="http://www.joeyoder.com/">Joseph Yoder</A>
</B> <BR /> <I><B><A HREF="../metamorphosis/metamorphosis.html">Architecture,
Evolution, and Metamorphosis</A></B></I><BR> <I><B><A
HREF="../selfish/selfish.html">The Selfish Class</A></B></I><BR />
</font>
</p>
<p align="CENTER">
<font size=2> This paper was twice <A
HREF="http://slashdot.org/articles/00/04/29/0926241.shtml">featured</A>
in <b> <A HREF="http://slashdot.org/">Slashdot</A>
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<A NAME="Contents"></A>
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<tr>
<td width="100%" bgcolor="#808080" style="border: 0px">
<p align="center">
<font color="#FFFFFF" size="5"> <b>Contents</b>
</font>
</td>
</tr>
</table>
<!-- End of Pattern Header -->
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align="RIGHT" hspace=10 vspace=15
src="../images/pictures/harrison-small.jpg" alt="PLoPD4 Cover"></A>
<OL>
<LI><A HREF="mud.html#Abstract">Abstract</A>
<LI><A HREF="mud.html#Introduction">Introduction</A>
<LI><A HREF="mud.html#Forces">Forces</A>
<LI><A HREF="mud.html#BigBallOfMud">Big Ball Of Mud</A>
<LI><A HREF="mud.html#ThrowAwayCode">Throwaway Code</A>
<LI><A HREF="mud.html#PiecemealGrowth">Piecemeal Growth</A>
<LI><A HREF="mud.html#KeepItWorking">Keep It Working</A>
<LI><A HREF="mud.html#ShearingLayers">Shearing Layers</A>
<LI><A HREF="mud.html#SweepingItUnderTheRug">Sweeping It
Under The Rug</A>
<LI><A HREF="mud.html#Reconstruction">Reconstruction</A>
<LI><A HREF="mud.html#Conclusion">Conclusion</A>
<LI><A HREF="mud.html#Acknowledgments">Acknowledgments</A>
<LI><A HREF="mud.html#References">References</A>
</OL>
<!-- Pattern Header -->
<A NAME="Abstract"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px">
<p align="center">
<font color="#FFFFFF" size="5"> <b>Abstract</b>
</font>
</td>
</tr>
</table>
<!-- End of Pattern Header -->
<p>
While much attention has been focused on high-level software
architectural patterns, what is, in effect, the de-facto standard
software architecture is seldom discussed. This paper examines this
most frequently deployed of software architectures: the <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A>. A <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A> is a casually, even
haphazardly, structured system. Its organization, if one can call it
that, is dictated more by expediency than design. Yet, its enduring
popularity cannot merely be indicative of a general disregard for
architecture.
</p>
<p>
These patterns explore the forces that encourage the emergence of a <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A>, and the undeniable
effectiveness of this approach to software architecture. What are the
people who build them doing right? If more high-minded architectural
approaches are to compete, we must understand what the forces that
lead to a <A HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A> are, and
examine alternative ways to resolve them.
</p>
<p>
A number of additional patterns emerge out of the <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A>. We discuss them in
turn. Two principal questions underlie these patterns: Why are so many
existing systems architecturally undistinguished, and what can we do
to improve them?
</p>
<!-- Pattern Header -->
<A NAME="Introduction"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px">
<p align="center">
<font color="#FFFFFF" size="5"> <b>Introduction</b>
</font>
</td>
</tr>
</table>
<!-- End of Pattern Header -->
<p>
Over the last several years, a number of authors [Garlan & Shaw
1993] [Shaw 1996] [Buschmann et. al. 1996] [Meszaros 1997] have
presented patterns that characterize high-level software
architectures, such as PIPELINE and LAYERED ARCHITECTURE. In an ideal
world, every system would be an exemplar of one or more such
high-level patterns. Yet, this is not so. The architecture that
actually predominates in practice has yet to be discussed: the <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A>.
</p>
<A HREF="http://oak.cats.ohiou.edu/~ba116594/mmt.html"> <IMG
SRC="../images/pictures/spaghetti-medium.jpg" width=317 height=437
hspace=10 align=right alt="Lennon Serves Too Much Spaghetti"></A>
<p>
A <A HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A> is haphazardly
structured, sprawling, sloppy, duct-tape and bailing wire, <a
href="http://www.mdagroup.com/computing/spaghett.htm">spaghetti</a> <a
href="http://www.cs.brandeis.edu/~dkw/C-humor/pasta.txt">code</a> <a
href="http://leb.net/~tonyk/jargon/entry.cgi?idx=1710">jungle</A>.
We’ve all seen them. These systems show unmistakable signs of
unregulated growth, and repeated, <A
HREF="http://home.swbell.net/mck9/cobol/style/rewrite.html">expedient</A>
repair. Information is shared promiscuously among distant elements of
the system, often to the point where nearly all the important
information becomes global or duplicated. The overall structure of the
system may never have been well defined. If it was, it may have <A
HREF="http://garynorth.com/y2k/detail_.cfm/881">eroded</A> beyond
recognition. Programmers with a shred of architectural sensibility
shun these quagmires. Only those who are unconcerned about
architecture, and, perhaps, are comfortable with the inertia of the
day-to-day chore of patching the holes in these failing dikes, are
content to work on such systems.
</p>
<p>Still, this approach endures and thrives. Why is this
architecture so popular? Is it as bad as it seems, or might it serve
as a way-station on the road to more enduring, elegant artifacts? What
forces drive good programmers to build ugly systems? Can we avoid
this? Should we? How can we make such systems better?</p>
<p>We present the following seven patterns:</p>
<dir>
<p>
<IMG SRC="../images/icons/blueball.gif" /> <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A>
</p>
<IMG SRC="../images/icons/blueball.gif" />
<A HREF="mud.html#ThrowAwayCode">THROWAWAY CODE</A>
</p>
<p>
<IMG SRC="../images/icons/blueball.gif" /> <A
HREF="mud.html#PiecemealGrowth">PIECEMEAL GROWTH</A>
</p>
<p>
<IMG SRC="../images/icons/blueball.gif" /> <A
HREF="mud.html#KeepItWorking">KEEP IT WORKING</A>
</p>
<p>
<IMG SRC="../images/icons/blueball.gif" /> <A
HREF="mud.html#ShearingLayers">SHEARING LAYERS</A>
</p>
<p>
<IMG SRC="../images/icons/blueball.gif" /> <A
HREF="mud.html#SweepingItUnderTheRug">SWEEPING IT UNDER THE RUG</A>
</p>
<p>
<IMG SRC="../images/icons/blueball.gif" /> <A
HREF="mud.html#Reconstruction">RECONSTRUCTION</A>
</p>
</dir>
<p>
Why does a system become a <A HREF="mud.html#BigBallOfMud">BIG
BALL OF MUD</A>? Sometimes, big, ugly systems emerge from <A
HREF="mud.html#ThrowAwayCode"></A><A HREF="mud.html#ThrowAwayCode">THROWAWAY
CODE</A>. <A HREF="mud.html#ThrowAwayCode">THROWAWAY CODE</A> is
quick-and-dirty code that was intended to be used only once and then
discarded. However, such code often takes on a life of its own,
despite casual structure and poor or non-existent documentation. It
works, so why fix it? When a related problem arises, the quickest way
to address it might be to expediently modify this working code, rather
than design a proper, general program from the ground up. Over time, a
simple throwaway program begets a <A HREF="mud.html#BigBallOfMud">BIG
BALL OF MUD</A>.
</p>
<p>
Even systems with well-defined architectures are prone to structural
erosion. The relentless onslaught of changing requirements that any
successful system attracts can gradually undermine its structure.
Systems that were once tidy become overgrown as <A
HREF="mud.html#PiecemealGrowth">PIECEMEAL GROWTH</A> gradually allows
elements of the system to sprawl in an uncontrolled fashion.
</p>
<p>
If such sprawl continues unabated, the structure of the system can
become so badly compromised that it must be abandoned. As with a
decaying neighborhood, a downward spiral ensues. Since the system
becomes harder and harder to understand, maintenance becomes more
expensive, and more difficult. Good programmers refuse to work there.
Investors withdraw their capital. And yet, as with neighborhoods,
there are ways to avoid, and even reverse, this sort of decline. As
with anything else in the universe, counteracting entropic forces
requires an investment of energy. Software <A
HREF="http://www.m-w.com/cgi-bin/dictionary?gentrification">gentrification</A>
is no exception. The way to arrest entropy in software is to refactor
it. A sustained commitment to refactoring can keep a system from
subsiding into a BIG BALL OF MUD.
</p>
<p>
A major flood, fire, or war may require that a city be evacuated and
rebuilt from the ground up. More often, change takes place a building
or block at a time, while the city as a whole continues to function.
Once established, a strategy of <A HREF="mud.html#KeepItWorking">KEEPING
IT WORKING</A> preserves a municipality’s vitality as it grows.
</p>
<p>
Systems and their constituent elements evolve at different rates. As
they do, things that change quickly tend to become distinct from
things that change more slowly. The <A HREF="mud.html#ShearingLayers">SHEARING
LAYERS</A> that develop between them are like fault lines or facets that
help foster the emergence of enduring abstractions.
</p>
<p>
A simple way to begin to control decline is to cordon off the blighted
areas, and put an attractive façade around them. We call this strategy
<A HREF="mud.html#SweepingItUnderTheRug">SWEEPING IT UNDER THE RUG</A>.
In more advanced cases, there may be no alternative but to tear
everything down and start over. When total <A
HREF="mud.html#Reconstruction">RECONSTRUCTION</A> becomes necessary,
all that is left to salvage is the patterns that underlie the
experience.
</p>
<p>Some of these patterns might appear at first to be antipatterns
[Brown et al. 1998] or straw men, but they are not, at least in the
customary sense. Instead, they seek to examine the gap between what we
preach and what we practice.</p>
<p>Still, some of them may strike some readers as having a schizoid
quality about them. So, for the record, let us put our cards on the
table. We are in favor of good architecture.</p>
<p>Our ultimate agenda is to help drain these swamps. Where
possible, architectural decline should be prevented, arrested, or
reversed. We discuss ways of doing this. In severe cases,
architectural abominations may even need to be demolished.</p>
<p>At the same time, we seek not to cast blame upon those who must
wallow in these mires. In part, our attitude is to "hate the sin, but
love the sinner". But, it goes beyond this. Not every backyard storage
shack needs marble columns. There are significant forces that can
conspire to compel architecture to take a back seat to functionality,
particularly early in the evolution of a software artifact.
Opportunities and insights that can allow for architectural progress
often are present later rather than earlier in the lifecycle.</p>
<p>A certain amount of controlled chaos is natural during
construction, and can be tolerated, as long as you clean up after
yourself eventually. Even beyond this though, a complex system may be
an accurate reflection of our immature understanding of a complex
problem. The class of systems that we can build at all may be larger
than the class of systems we can build elegantly, at least at first. A
somewhat ramshackle rat's nest might be a state-of-the-art
architecture for a poorly understood domain. This should not be the
end of the story, though. As we gain more experience in such domains,
we should increasingly direct our energies to gleaning more enduring
architectural abstractions from them.</p>
<p>
The patterns described herein are not intended to stand alone. They
are instead set in a context that includes a number of other patterns
that we and others have described. In particular, they are set in
contrast to the lifecycle patterns, <A
HREF="http://www.bell-labs.com/user/cope/Patterns/Process/section38.html">PROTOTYPE</A>
<A HREF="../lifecycle/lifecycle.html#Prototype">PHASE</A>, <A
HREF="../lifecycle/lifecycle.html#Expand">EXPANSIONARY PHASE</A>, and
<A HREF="../lifecycle/lifecycle.html#Consolidate">CONSOLIDATION
PHASE</A>, presented in [<A HREF="../lifecycle/lifecycle.html">Foote
& Opdyke 1995</A>] and [Coplien 1995], the <A
HREF="../metamorphosis/metamorphosis.html#SoftwareTectonics">SOFTWARE
TECTONICS</A> pattern in [<A
HREF="../metamorphosis/metamorphosis.html#SoftwareTectonics">Foote
& Yoder 1996</A>], and the framework development patterns in [<A
HREF="http://st-www.cs.uiuc.edu/~droberts/evolve.html">Roberts
& Johnson 1998</A>].
</p>
<p>Indeed, to a substantial extent, much of this chapter describes
the disease, while the patterns above describe what we believe can be
the cure: a flexible, adaptive, feedback-driven development process in
which design and refactoring pervade the lifecycle of each artifact,
component, and framework, within and beyond the applications that
incubate them.</p>
<!-- Pattern Header -->
<A NAME="Forces"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px">
<p align="center">
<font color="#FFFFFF" size="5"> <b>Forces</b>
</font>
</td>
</tr>
</table>
<!-- End of Pattern Header -->
<p>
A number of forces can conspire to drive even the most architecturally
conscientious organizations to produce <A HREF="mud.html#BigBallOfMud">BIG
BALLS OF MUD</A>. These pervasive, <I>"global" forces</I> are
at work in all the patterns presented. Among these forces:
</p>
<p>
<i>Time:</i> There may not be enough <u>time</u> to consider the <A
HREF="http://www.longnow.org/">long-term</A> architectural
implications of one’s design and implementation decisions. Even
when systems have been well designed, architectural concerns often
must yield to more pragmatic ones as a deadline starts to loom.
</p>
<p>
One reason that software architectures are so often mediocre is that
architecture frequently takes a back seat to more mundane concerns
such as cost, time-to-market, and programmer skill. Architecture is
often seen as a luxury or a frill, or the indulgent pursuit of
lily-gilding compulsives who have no concern for the bottom line.
Architecture is often treated with neglect, and even disdain. While
such attitudes are unfortunate, they are not hard to understand.
Architecture is a long-term concern. The concerns above have to be
addressed if a product is not to be stillborn in the marketplace,
while the benefits of good architecture are realized later in the
lifecycle, as frameworks mature, and reusable black-box components
emerge [<A HREF="../lifecycle/lifecycle.html">Foote & Opdyke
1995</A>].
</p>
<p>
Architecture can be looked upon as a <i>Risk</i>, that will consume
resources better directed at meeting a fleeting market window, or as
an <i>Opportunity</i> to lay the groundwork for a commanding advantage
down the road.
</p>
<p>Indeed, an immature architecture can be an advantage in a
growing system because data and functionality can migrate to their
natural places in the system unencumbered by artificial architectural
constraints. Premature architecture can be more dangerous than none at
all, as unproved architectural hypotheses turn into straightjackets
that discourage evolution and experimentation.</p>
<p>
<i>Cost:</i> Architecture is expensive, especially when a new domain
is being explored. Getting the system right seems like a pointless
luxury once the system is limping well enough to ship. An investment
in architecture usually does not pay off immediately. Indeed, if
architectural concerns delay a product’s market entry for too
long, then long-term concerns may be moot. Who benefits from an
investment in architecture, and when is a return on this investment
seen? Money spent on a quick-and-dirty project that allows an
immediate entry into the market may be better spent than money spent
on elaborate, speculative architectural fishing expedition. It’s
hard to recover the value of your architectural assets if you’ve
long since gone bankrupt.
</p>
<p>Programmers with the ability to discern and design quality
architectures are reputed to command a premium. These expenses must be
weighed against those of allowing an expensive system to slip into
premature decline and obsolescence. If you think good architecture is
expensive, try bad architecture.</p>
<p>
<i>Experience:</i> Even when one has the time and inclination to take
architectural concerns into account, one’s experience, or lack
thereof, with the domain can limit the degree of architectural
sophistication that can be brought to a system, particularly early in
its evolution. Some programmers flourish in environments where they
can discover and develop new abstractions, while others are more
comfortable in more constrained environments (for instance, Smalltalk
vs. <A HREF="http://www.hamline.edu/~wnk/cpb/199707/0884.html">Visual
Basic</A> programmers.) Often, initial versions of a system are vehicles
whereby programmers learn what pieces must be brought into play to
solve a particular problem. Only after these are identified do the
architectural boundaries among parts of the system start to emerge.
</p>
<p>Inexperience can take a number of guises. There is absolute,
fresh out of school inexperience. A good architect may lack domain
experience, or a domain expert who knows the code cold may not have
architectural experience.</p>
<p>Employee turnover can wreak havoc on an organization’s
institutional memory, with the perhaps dubious consolation of bringing
fresh blood aboard.</p>
<p>
<i>Skill:</i> Programmers differ in their levels of skill, as well as
in expertise, predisposition and temperament. Some programmers have a
passion for finding good abstractions, while some are skilled at
navigating the swamps of complex code left to them by others.
Programmers differ tremendously in their degrees of experience with
particular domains, and their capacities for adapting to new ones.
Programmers differ in their language and tool preferences and
experience as well.
</p>
<p>
<i>Visibility:</i> Buildings are tangible, physical structures. You
can look at a building. You can watch it being built. You can walk
inside it, and admire and critique its design.
</p>
<p>A program’s user interface presents the public face of a
program, much as a building’s exterior manifests its
architecture. However, unlike buildings, only the people who build a
program see how it looks inside.</p>
<p>Programs are made of bits. The manner in which we present these
bits greatly affects our sense of how they are put together. Some
designers prefer to see systems depicted using modeling languages or
PowerPoint pictures. Others prefer prose descriptions. Still others
prefer to see code. The fashion in which we present our architectures
affects our perceptions of whether they are good or bad, clear or
muddled, and elegant or muddy.</p>
<p>Indeed, one of the reasons that architecture is neglected is
that much of it is "under the hood", where nobody can see
it. If the system works, and it can be shipped, who cares what it
looks like on the inside?</p>
<p>
<i>Complexity:</i> One reason for a muddled architecture is that
software often reflects the inherent complexity of the application
domain. This is what <A
HREF="http://groucho.admin.unc.edu/endeavors/end496/brooks.htm">Brooks</A>
called "essential complexity" [Brooks 1995]. In other words,
the software is ugly because the problem is ugly, or at least not well
understood. Frequently, the organization of the system reflects the
sprawl and history of the organization that built it (as per <A
HREF="http://www.bell-labs.com/user/cope/Patterns/Process/section15.html">CONWAY’S
LAW</A> [Coplien 1995]) and the compromises that were made along the way.
Renegotiating these relationships is often difficult once the basic
boundaries among system elements are drawn. These relationships can
take on the immutable character of "site" boundaries that <A
HREF="http://www.well.com/user/sbb/index.html"> Brand</A> [Brand
1994] observed in real cities. Big problems can arises when the needs
of the applications force unrestrained communication across these
boundaries. The system becomes a tangled mess, and what little
structure is there can erode further.
</p>
<p>
<i>Change:</i> Architecture is a hypothesis about the future that
holds that subsequent change will be confined to that part of the
design space encompassed by that architecture. Of course, the world
has a way of mocking our attempts to make such predictions by tossing
us the totally unexpected. A problem we might have been told was
definitely ruled out of consideration for all time may turn out to be
dear to the heart of a new client we never thought we’d have.
Such changes may cut directly across the grain of fundamental
architectural decisions made in the light of the certainty that these
new contingencies could never arise. The "right" thing to do
might be to redesign the system. The more likely result is that the
architecture of the system will be expediently perturbed to address
the new requirements, with only passing regard for the effect of these
radical changes on the structure of the system.
</p>
<p>
<i>Scale:</i> Managing a large project is a qualitatively different
problem from managing a small one, just as leading a division of
infantry into battle is different from commanding a small special
forces team. Obviously, "divide and conquer" is, in general, an
insufficient answer to the problems posed by scale. Alan Kay, during
an invited talk at OOPSLA '86 observed that "good ideas don't always
scale." That observation prompted <A
HREF="http://lcs.www.media.mit.edu/people/lieber/">Henry
Lieberman</A> to inquire "so what do we do, just scale the bad ones?"
</p>
<A NAME="BigBallOfMud"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px"><font
size="5" color="#ffffff"><p align="CENTER">
<b>BIG BALL OF MUD</font></b></td>
</tr>
</table>
<table border="0" width="100%" bgcolor="#FFFF00" cellspacing="0"
cellpadding="0">
<tr>
<td width="100%" align="center"><i>alias</i></td>
<b>
</tr>
<tr>
</b>
<td width="100%" align="center">SHANTYTOWN</td>
<b>
</tr>
<tr>
</b>
<td width="100%" align="center">SPAGHETTI CODE</td>
<b>
</tr>
</table>
</b>
<p align="center">
<A HREF="http://boone.calstatela.edu/spring476/prasarangkul.htm">
<img src="../images/pictures/squat.jpg" width="457" height="310"
alt="Shantytown">
</A>
</p>
<p>
<A HREF="http://www.interlog.com/~rodneyb/paraguay/shantypix.html">Shantytowns</A>
are squalid, sprawling slums. Everyone seems to agree they are a bad
idea, but forces conspire to promote their emergence anyway. What is
it that they are doing right?
</p>
<p>Shantytowns are usually built from common, inexpensive materials
and simple tools. Shantytowns can be built using relatively unskilled
labor. Even though the labor force is "unskilled" in the
customary sense, the construction and maintenance of this sort of
housing can be quite labor intensive. There is little specialization.
Each housing unit is constructed and maintained primarily by its
inhabitants, and each inhabitant must be a jack of all the necessary
trades. There is little concern for infrastructure, since
infrastructure requires coordination and capital, and specialized
resources, equipment, and skills. There is little overall planning or
regulation of growth. Shantytowns emerge where there is a need for
housing, a surplus of unskilled labor, and a dearth of capital
investment. Shantytowns fulfill an immediate, local need for housing
by bringing available resources to bear on the problem. Loftier
architectural goals are a luxury that has to wait.</p>
<p>Maintaining a shantytown is labor-intensive and requires a broad
range of skills. One must be able to improvise repairs with the
materials on-hand, and master tasks from roof repair to ad hoc
sanitation. However, there is little of the sort of skilled
specialization that one sees in a mature economy.</p>
<p>All too many of our software systems are, architecturally,
little more than shantytowns. Investment in tools and infrastructure
is too often inadequate. Tools are usually primitive, and
infrastructure such as libraries and frameworks, is undercapitalized.
Individual portions of the system grow unchecked, and the lack of
infrastructure and architecture allows problems in one part of the
system to erode and pollute adjacent portions. Deadlines loom like
monsoons, and architectural elegance seems unattainable.</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>As a system nears completion, its actual users may begin to work
with it for the first time. This experience may inspire changes to
data formats and the user interface that undermine architectural
decisions that had been thought to be settled. Also, as Brooks [Brooks
1995] has noted, because software is so flexible, it is often asked to
bear the burden of architectural compromises late in the development
cycle of hardware/software deliverables precisely because of its
flexibility.</p>
<p>
This phenomenon is not unique to software. <A
HREF="http://www.well.com/user/sbb/index.html">Stewart Brand</A>
[Brand 1994] has observed that the period just prior to a
building’s initial occupancy can be a stressful period for both
architects and their clients. The money is running out, and the
finishing touches are being put on just those parts of the space that
will interact the most with its occupants. During this period, it can
become evident that certain wish-list items are not going to make it,
and that exotic experiments are not going to work. Compromise becomes
the "order of the day".
</p>
<p>The time and money to chase perfection are seldom available, nor
should they be. To survive, we must do what it takes to get our
software working and out the door on time. Indeed, if a team completes
a project with time to spare, today’s managers are likely to take
that as a sign to provide less time and money or fewer people the next
time around.</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><font><b>You need to deliver quality
software on time, and under budget.</b></font></td>
</tr>
</table>
<p>
<i>Cost</i>: Architecture is a long-term investment. It is easy for
the people who are paying the bills to dismiss it, unless there is
some tangible immediate benefit, such a tax write-off, or unless
surplus money and time happens to be available. Such is seldom the
case. More often, the customer needs something working by tomorrow.
Often, the people who control and manage the development process
simply do not regard architecture as a pressing concern. If
programmers know that workmanship is invisible, and managers don't
want to pay for it anyway, a vicious circle is born.
</p>
<p>
<i>Skill</i>: Ralph Johnson is fond of observing that is inevitable
that "on average, average organizations will have average people". One
reason for the popularity and success of <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A> approaches might be
that this appoach doesn't require a hyperproductive <A
HREF="http://www.onenet.net/~njtdb/casey.html">virtuoso</A> architect
at every keyboard.
<p>
<p>
<i>Organization</i>: With larger projects, cultural, process,
organizational and resource allocation issues can overwhelm technical
concerns such as tools, languages, and architecture.
</p>
<p>It may seem to a programmer that whether to don hip boots and
wade into a swamp is a major quality-of-life matter, but programmer
comfort is but one concern to a manager, which can conflict with many
others. Architecture and code quality may strike management as frills
that have only an indirect impact on their bottom lines.
<p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><b><font><u><i>Therefore</i></u>,
focus first on features and functionality, then focus on
architecture and performance. </font></b></td>
</tr>
</table>
<p>
The case made here resembles Gabriel’s "<A
HREF="../gabriel/worse-is-better.html">Worse is Better</A>"
arguments [Gabriel 1991] in a number of respects. Why does so much
software, despite the best intentions and efforts of developers, turn
into <A HREF="mud.html#BigBallOfMud">BIG BALLS OF MUD</A>? Why do
slash-and-burn tactics drive out elegance? Does bad architecture drive
out good architecture?
</p>
<p>What does this muddy code look like to the programmers in the
trenches who must confront it? Data structures may be haphazardly
constructed, or even next to non-existent. Everything talks to
everything else. Every shred of important state data may be global.
There are those who might construe this as a sort of blackboard
approach [Buschmann 1996], but it more closely resembles a grab bag of
undifferentiated state. Where state information is compartmentalized,
it may be passed promiscuously about though Byzantine back channels
that circumvent the system's original structure.</p>
<p>Variable and function names might be uninformative, or even
misleading. Functions themselves may make extensive use of global
variables, as well as long lists of poorly defined parameters. The
function themselves are lengthy and convoluted, and perform several
unrelated tasks. Code is duplicated. The flow of control is hard to
understand, and difficult to follow. The programmer’s intent is
next to impossible to discern. The code is simply unreadable, and
borders on indecipherable. The code exhibits the unmistakable signs of
patch after patch at the hands of multiple maintainers, each of whom
barely understood the consequences of what he or she was doing. Did we
mention documentation? What documentation?</p>
<p>
<A HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A> might be thought
of as an anti-pattern, since our intention is to show how passivity in
the face of forces that undermine architecture can lead to a quagmire.
However, its undeniable popularity leads to the inexorable conclusion
that it is a pattern in its own right. It is certainly a pervasive,
recurring solution to the problem of producing a working system in the
context of software development. It would seem to be the path of least
resistance when one confronts the sorts of forces discussed above.
Only by understanding the logic of its appeal can we channel or
counteract the forces that lead to a <A HREF="mud.html#BigBallOfMud">BIG
BALL OF MUD</A>.
</p>
<p>One thing that isn’t the answer is rigid, totalitarian,
top-down design. Some analysts, designers, and architects have an
exaggerated sense of their ability to get things right up-front,
before moving into implementation. This approach leads to inefficient
resources utilization, analysis paralysis, and design straightjackets
and cul-de-sacs.</p>
<p>Kent Beck has observed that the way to build software is to:
Make it work. Make it right. Make it fast [Beck 1997]. "Make it
work" means that we should focus on functionality up-front, and
get something running. "Make it right" means that we should
concern ourselves with how to structure the system only after
we’ve figured out the pieces we need to solve the problem in the
first place. "Make it fast" means that we should be
concerned about optimizing performance only after we’ve learned
how to solve the problem, and after we’ve discerned an
architecture to elegantly encompass this functionality. Once all this
has been done, one can consider how to make it cheap.</p>
<p>
When it comes to software architecture, form <u>follows</u> function.
Here we mean "follows" not in the traditional sense of dictating
function. Instead, we mean that the distinct identities of the
systems architectural elements often dont start to emerge until <u>after</u>
the code is working.
</p>
<p>Domain experience is an essential ingredient in any framework
design effort. It is hard to try to follow a front-loaded, top-down
design process under the best of circumstances. Without knowing the
architectural demands of the domain, such an attempt is premature, if
not foolhardy. Often, the only way to get domain experience early in
the lifecycle is to hire someone who has worked in a domain before
from someone else.</p>
<p>The quality of one’s tools can influence a system’s
architecture. If a system’s architectural goals are inadequately
communicated among members of a team, they will be harder to take into
account as the system is designed and constructed.</p>
<p>
Finally, engineers will differ in their levels of skill and commitment
to architecture. Sadly, architecture has been undervalued for so long
that many engineers regard life with a <A HREF="mud.html#BigBallOfMud">BIG
BALL OF MUD</A> as normal. Indeed some engineers are particularly skilled
at learning to navigate these quagmires, and guiding others through
them. Over time, this symbiosis between architecture and skills can
change the character of the organization itself, as swamp guides
become more valuable than architects. As per <A
HREF="http://www.bell-labs.com/user/cope/Patterns/Process/section15.html">CONWAY’S
LAW</A> [Coplien 1995], architects depart in futility, while engineers
who have mastered the muddy details of the system they have built in
their images prevail. [<A
HREF="../selfish/selfish.html#LowSurfaceToVolumeRatio">Foote
& Yoder 1998a</A>] went so far as to observe that inscrutable code
might, in fact, have a survival advantage over good code, by virtue of
being difficult to comprehend and change. This advantage can extend to
those programmers who can find their ways around such code. In a land
devoid of landmarks, such guides may become indispensable.
</p>
<p>The incentives that drive the evolution of such systems can, at
times, operate perversely. Just as it is easier to be verbose than
concise, it is easier to build complex systems than it is to build
simple ones. Skilled programmers may be able to create complexity more
quickly than their peers, and more quickly than they can document and
explain it. Like an army outrunning its logistics train, complexity
increases until it reaches the point where such programmers can no
longer reliably cope with it.</p>
<p>
This is akin to a phenonmenon dubbed the <A
HREF="http://www.c2.com/cgi/wiki?PeterPrincipleProgramming"><I>PeterPrinciple
of Programming</I></A> by authors on the Wiki-Wiki web [Cunninghan 1999a].
Complexity increases rapidly until the it reaches a level of
complexity just beyond that with which programmers can comfortably
cope. At this point, complexity and our abilities to contain it reach
an uneasy equilibrium. The blitzkrieg bogs down into a siege. We built
<A
HREF="http://www.c2.com/cgi/wiki?TheMostComplexWhichCanBeMadeToWork">
the most complicated system that can possible work</A> [Cunningham
1999b].
</p>
<A HREF="http://www.45thdivisionmuseum.com/Mainmuseum/Mauldin2.htm">
<IMG SRC="../images/pictures/mauldin-warm-mud.gif" ALIGN="right"
HSPACE=5 VSPACE=10>
</A>
<p>Such code can become a personal fiefdom, since the author care
barely understand it anymore, and no one else can come close. Once
simple repairs become all day affairs, as the code turns to mud. It
becomes increasingly difficult for management to tell how long such
repairs ought to take. Simple objectives turn into trench warfare.
Everyone becomes resigned to a turgid pace. Some even come to prefer
it, hiding in their cozy foxholes, and making their two line-per-day
repairs.</p>
<p>It is interesting to ask whether some of the differences in
productivity seen between hyper-productive organizations and typical
shops are due not to differences in talent, but differences in
terrain. Mud is hard to march through. The hacker in the trenches must
engage complexity in hand-to-hand combat every day. Sometimes,
complexity wins.</p>
<p>Status in the programmer's primate pecking order is often earned
through ritual displays of cleverness, rather than through
workman-like displays of simplicity and clarity. That which a culture
glorifies will flourish.</p>
<p>
Yet, a case can be made that the casual, undifferentiated structure of
a <A HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A> is one of its
secret advantages, since forces acting between two parts of the system
can be directly addressed without having to worry about undermining
the system’s grander architectural aspirations. These aspirations
are modest ones at best in the typical <A HREF="mud.html#BigBallOfMud">BIG
BALL OF MUD</A>. Indeed, a casual approach to architecture is emblematic
of the early phases of a system’s evolution, as programmers,
architects and users learn their way around the domain [<A
HREF="../lifecycle/lifecycle.html#Prototype">Foote & Opdyke
1995</A>]. During the <A HREF="../lifecycle/lifecycle.html#Prototype">PROTOTYPE</A>
and <A HREF="../lifecycle/lifecycle.html#Expand">EXPANSIONARY
PHASES</A> of a systems evolution, expedient, white-box inheritance-based
code borrowing, and a relaxed approach to encapsulation are common.
Later, as experience with the system accrues, the grain of the
architectural domain becomes discernable, and more durable black-box
components begin to emerge. In other words, it’s okay if the
system looks at first like a <A HREF="mud.html#BigBallOfMud">BIG
BALL OF MUD</A>, at least until you know better.
</p>
<p align="center">
<img src="../images/pictures/mud-house.gif" width="575" height="367"
alt="Mud-based Architecture">
</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>
<A HREF="http://www.stlabs.com/marick/root.htm">Brian Marick</A> first
suggested the name "<A HREF="mud.html#BigBallOfMud">BIG BALL
OF MUD</A>" as a name for these sort of architectures, and the
observation that this was, perhaps, the dominant architecture
currently deployed, during a meeting of the <A
HREF="http://st-www.cs.uiuc.edu/research-gp.html"> University of
Illinois Software Architecture Group</A> several years ago. We have been
using the term ever since. The term itself, in turn, appears to have <A
HREF="http://www.bath.ac.uk/~masjap/TYL/history.html">arisen</A>
during the '70s as a <A
HREF="http://www.cs.unm.edu/~hollan/cs257/description.html">characterization</A>
of <A
HREF="http://www.cosc.canterbury.ac.nz/~wolfgang/cosc302/Chap2.3.html">Lisp</A>.
</p>
<p>
<A HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A> architectures
often emerge from throw-away prototypes, or <A
HREF="mud.html#ThrowAwayCode">THROWAWAY CODE</A>, because the
prototype is kept, or the disposable code is never disposed of. (One
might call these "<A HREF="http://www.muang.com/rice/plant.html">little
balls of mud</A>".)
</p>
<p>
They also can emerge as gradual maintenance and <A
HREF="mud.html#PiecemealGrowth">PIECEMEAL GROWTH</A> impinges upon
the structure of a mature system. Once a system is working, a good way
to encourage its growth is to <A HREF="mud.html#KeepItWorking">KEEP
IT WORKING</A>. When the <A HREF="mud.html#ShearingLayers">SHEARING
LAYERS</A> that emerge as change drives the system's evolution run
against the existing grain of the system, its structure can be
undermined, and the result can be a <A HREF="mud.html#BigBallOfMud">BIG
BALL OF MUD</A>.
</p>
<p>
The <A HREF="../lifecycle/lifecycle.html#Prototype">PROTOTYPE
PHASE</A> and <A HREF="../lifecycle/lifecycle.html#Expand">EXPANSION
PHASE</A> patterns in [<A HREF="../lifecycle/lifecycle.html">Foote
& Opdyke 1995</A>] both emphasize that a period of exploration and
experimentation is often beneficial before making enduring
architectural commitments.
</p>
<p>
However, these activities, which can undermine a system's structure
should be interspersed with <A
HREF="../lifecycle/lifecycle.html#Consolidate">CONSOLIDATION
PHASES</A> [<A HREF="../lifecycle/lifecycle.html">Foote & Opdyke
1995</A>], during which opportunities to refactor the system to enhance
its structure are exploited. Proponents of <A
HREF="http://www.xprogramming.com">Extreme Programming</A> [Beck
2000] also emphasize continuous coding and refactoring.
</p>
<p>
[Brand 1994] observes that buildings with large spaces punctuated with
regular columns had the paradoxical effect of encouraging the
innovative reuse of space precisely <u>because</u> they <A
HREF="../chaos/chaos.html"><i>constrained</i></A> the design space.
Grandiose flights of architectural fancy weren’t possible, which
reduced the number of design alternatives that could be put on the
table. Sometimes <A HREF="../dfc/discussion.html#O2isEasy">FREEDOM
FROM CHOICE</A> [Foote 1988] is what we <u>really</u> want.
</p>
<p>One of mud's most effective enemies is sunshine. Subjecting
convoluted code to scrutiny can set the stage for its refactoring,
repair, and rehabilitation. Code reviews are one mechanism one can use
to expose code to daylight.</p>
<p>
Another is the <A HREF="http://www.xprogramming.com">Extreme
Programming</A> practice of pair programming [Beck 2000]. A pure pair
programming approach requires that every line of code written be added
to the system with two programmers present. One types, or "drives",
while the other "rides shotgun" and looks on. In contrast to
traditional solitary software production practices, pair programming
subjects code to immediate scrutiny, and provides a means by which
knowledge about the system is rapidly disseminated.
</p>
<p>Indeed, reviews and pair programming provide programmers with
something their work would not otherwise have: an audience. Sunlight,
it is said is a powerful disinfectant. Pair-practices add an element
of performance to programming. An immediate audience of one's peers
provides immediate incentives to programmers to keep their code clear
and comprehensible, as well as functional.</p>
<p>
An additional benefit of pairing is that accumulated wisdom and best
practices can be <A HREF="../chaos/chaos.html">rapidly
disseminated</A> throughout an organization through successive pairings.
This is, incidentally, the same benefit that sexual reproduction
brought to the genome.
</p>
<p>By contrast, if no one ever looks at code, everyone is free to
think they are better than average at producing it. Programmers will,
instead, respond to those relatively perverse incentives that do
exist. Line of code metrics, design documents, and other indirect
measurements of progress and quality can become central concerns.</p>
<p>
There are three ways to deal with <A HREF="mud.html#BigBallOfMud">BIG
BALLS OF MUD</A>. The first is to keep the system healthy.
Conscientiously alternating periods of <A
HREF="../lifecycle/lifecycle.html#Expand">EXPANSION</A> with periods
of <A HREF="../lifecycle/lifecycle.html#Consolidate">CONSOLIDATION</A>,
refactoring and repair can maintain, and even enhance a system's
structure as it evolves. The second is to throw the system away and
start over. The <A HREF="mud.html#Reconstruction">RECONSTRUCTION</A>
pattern explores this drastic, but frequently necessary alternative.
The third is to simply surrender to entropy, and wallow in the mire.
</p>
<p>
Since the time of Roman architect <A
HREF="http://www.cs.cmu.edu/afs/cs.cmu.edu/project/vit/www/index.html">Marcus
Vitruvius</A>, [<A
HREF="http://www.ukans.edu/history/index/europe/ancient_rome/E/Roman/Texts/Vitruvius/home*.html">Vitruvius
20 B.C.</A>] architects have focused on his trinity of desirables: <I>Firmitas</I>
(<B>strength</B>), <I>Utilitas</I> (<B>utility</B>), and <I>Venustas</I>
(<B>beauty</B>). A <A HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A>
usually represents a triumph of utility over aesthetics, because
workmanship is sacrificed for functionality. Structure and durability
can be sacrificed as well, because an incomprehensible program defies
attempts at maintenance. The frenzied, feature-driven "bloatware"
phenomenon seen in many large consumer software products can be seen
as evidence of designers having allowed purely utilitarian concerns to
dominate software design.
</p>
<p> </p>
<A NAME="ThrowAwayCode"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px"><p
align="CENTER">
<font size="5" color="#ffffff"><strong>THROWAWAY
CODE</strong></font>
</p></td>
</tr>
</table>
<table border="0" width="100%" bgcolor="#FFFF00" cellspacing="0"
cellpadding="0">
<tr>
<td width="100%" align="center"><i>alias </i></td>
</tr>
<tr>
<td width="100%" align="center">QUICK HACK</td>
</tr>
<tr>
<td width="100%" align="center">KLEENEX CODE</td>
</tr>
<tr>
<td width="100%" align="center">DISPOSABLE CODE</td>
</tr>
<tr>
<td width="100%" align="center">SCRIPTING</td>
</tr>
<tr>
<td width="100%" align="center">KILLER DEMO</td>
</tr>
<tr>
<td width="100%" align="center">PERMANENT PROTOTYPE</td>
</tr>
<tr>
<td width="100%" align="center">BOOMTOWN</td>
</tr>
</table>
<p> </p>
<p align="center">
<A HREF="http://www.users.csbsju.edu/~jwberndt/garbage.html"> <IMG
SRC="../images/pictures/landfill.jpg" hspace=10 width=258 height=372></A>
</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>A homeowner might erect a temporary storage shed or car port,
with every intention of quickly tearing it down and replacing it with
something more permanent. Such structures have a way of enduring
indefinitely. The money expected to replace them might not become
available. Or, once the new structure is constructed, the temptation
to continue to use the old one for "a while" might be hard
to resist.</p>
<p>Likewise, when you are prototyping a system, you are not usually
concerned with how elegant or efficient your code is. You know that
you will only use it to prove a concept. Once the prototype is done,
the code will be thrown away and written properly. As the time nears
to demonstrate the prototype, the temptation to load it with
impressive but utterly inefficient realizations of the system’s
expected eventual functionality can be hard to resist. Sometimes, this
strategy can be a bit too successful. The client, rather than funding
the next phase of the project, may slate the prototype itself for
release.</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><font><b>You need an immediate fix
for a small problem, or a quick prototype or proof of concept.</b></font></td>
</tr>
</table>
<p>
<font><i>Time</i>, or a lack thereof, is frequently the
decisive force that drives programmers to write <A
HREF="mud.html#ThrowAwayCode">THROWAWAY CODE</A>. Taking the time to
write a proper, well thought out, well documented program might take
more time that is available to solve a problem, or more time that the
problem merits. Often, the programmer will make a frantic dash to
construct a minimally functional program, while all the while
promising him or herself that a better factored, more elegant version
will follow thereafter. They may know full well that building a
reusable system will make it easier to solve similar problems in the
future, and that a more polished architecture would result in a
system that was easier to maintain and extend. </font>
</p>
<p>
<font> Quick-and-dirty coding is often rationalized as being a
stopgap measure. All too often, time is never found for this follow
up work. The code languishes, while the program flourishes.</font>
</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><b><u><i>Therefore</i></u>, produce, by any
means available, simple, expedient, disposable code that adequately
addresses just the problem at-hand.</b></td>
</tr>
</table>
<p>
<A HREF="mud.html#ThrowAwayCode">THROWAWAY CODE</A> is often written
as an alternative to reusing someone else’s more complex code.
When the deadline looms, the certainty that you can produce a sloppy
program that works yourself can outweigh the unknown cost of learning
and mastering someone else’s library or framework.
</p>
<p>
Programmers are usually not domain experts, especially at first. Use
cases or <A HREF="http://www.c2.com/doc/crc/draw.html">CRC</A> <a
href="http://www.du.edu/~mschwart/oo_review.html">cards</A> [<A
HREF="http://c2.com/doc/oopsla89/paper.html">Beck &
Cunningham 1989</A>] can help them to discover domain objects. However,
nothing beats building a prototype to help a team learn its way around
a domain.
</p>
<p>When you build a prototype, there is always the risk that
someone will say "that's good enough, ship it". One way to minimize
the risk of a prototype being put into production is to write the
prototype in using a language or tool that you couldn't possibly use
for a production version of your product. Proponents of
<p>
<A HREF="http://www.xprogramming.com">Extreme Programming</A> [Beck
2000] often construct quick, disposable prototypes called "spike
solutions". Prototypes help us learn our way around the problem space,
but should never be mistaken for good designs [<A
HREF="../drc/drc.html">Johnson & Foote 1988</A>].
</p>
Not every program need be a palace. A simple throwaway program is like
a tent city or a mining boomtown, and often has no need for fifty year
solutions to its problems, given that it will give way to a ghost town
in five.
<p></p>
The real problem with
<p>
<A HREF="mud.html#ThrowAwayCode">THROWAWAY CODE</A> comes when it
isn't thrown away.
</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>
The production of <A HREF="mud.html#ThrowAwayCode">THROWAWAY CODE</A>
is a nearly universal practice. Any software developer, at any skill
or experience level, can be expected to have had at least occasional
first-hand experience with this approach to software development. For
example, in the patterns community, two examples of quick-and-dirty
code that have endured are the <A
HREF="http://jerry.cs.uiuc.edu/plop/chili98/chili-register.html">PLoP
online registration</A> code, and the <A
HREF="http://c2.com/cgi/wiki?WelcomeVisitors">Wiki-Wiki Web</A>
pages.
</p>
<p>The EuroPLoP/PLoP/UP online registration code was, in effect, a
distributed web-based application that ran on four different machines
on two continents. Conference information was maintained on a machine
in St. Louis, while registration records were kept on machines in
Illinois and Germany. The system could generate web-based reports of
registration activity, and now even instantaneously maintaineed an
online attendees list. It began life in 1995 as a quick-and-dirty
collection of HTML, scavenged C demonstration code, and csh scripts.
It was undertaken largely as an experiment in web-based form
processing prior to PLoP ‘95, and, like so many things on the
Web, succeeded considerably beyond the expectations of its authors.
Today, it is still essentially the same collection of HTML, scavenged
C demonstration code, and csh scripts. As such, it showcases how
quick-and-dirty code can, when successful, take on a life of its own.</p>
<p>The original C code and scripts probably contained fewer than
three dozen original lines of code. Many lines were cut-and-paste jobs
that differed only in the specific text they generate, or fields that
they check.</p>
<p>Here’s an example of one of the scripts that generates the
attendance report:</p>
<font face="Lucida Sans Typewriter" size=2>
<p>
echo "<H2>Registrations: <B>" `ls | wc -l`
"</B></H2>"<br> echo
"<CODE>"<br> echo "Authors: <B>"
`grep 'Author = Yes' * | wc -l` "</B>"<br> echo
"<BR>"<br> echo "Non-Authors:
<B>" `grep 'Author = No' * | wc -l` "</B>"<br>
echo "<BR><BR>"
</p>
</font>
<p>
This script is slow and inefficient, particularly as the number of
registrations increases, but not least among its virtues is the fact
that it<i> works</i>. Were the number of attendees to exceed more than
around one hundred, this script would start to perform so badly as to
be unusable. However, since hundreds of attendees would exceed the
physical capacity of the conference site, we knew the number of
registrations would have been limited long before the performance of
this script became a significant problem. So while this approach is,
in general, a lousy way to address this problem, it is perfectly
satisfactory within the confines of the particular purpose for which
the script has ever actually been used. Such practical constraints are
typical of <A HREF="mud.html#ThrowAwayCode">THROWAWAY CODE</A>, and
are more often than not undocumented. For that matter, everything
about <A HREF="mud.html#ThrowAwayCode">THROWAWAY CODE</A> is more
often than not undocumented. When documentation exists, it is
frequently not current, and often not accurate.
</p>
<p>
The Wiki-Web <A HREF="http://c2.com/cgi/wiki?MoreAboutMechanics">code</A>
at <a href="http://www.c2.com">www.c2.com</a> also started as a CGI
experiment undertaken by Ward Cunningham also succeeded beyond the
author’s expectations. The name "wiki" is one of
Ward’s personal jokes, having been taken from a Hawaiian word for
"quick" that the author had seen on an airport van on a
vacation in Hawaii. Ward has subsequently used the name for a number
of quick-and-dirty projects. The Wiki Web is unusual in that <u>any</u>
visitor may change anything that anyone else has written
indiscriminately. This would seem like a recipe for vandalism, but in
practice, it has worked out well. In light of the system’s
success, the author has subsequently undertaken additional work to
polish it up, but the same quick-and-dirty Perl CGI core remains at
the heart of the system.
</p>
<p>
Both systems might be thought of as being on the verge of graduating
from little balls of mud to <A HREF="mud.html#BigBallOfMud">BIG
BALLS OF MUD</A>. The registration system’s C code <i><A
HREF="../dfc/discussion.html#Skeletons">metastasized</A></i> from one of
the NCSA HTTPD server demos, and still contains zombie code that
testifies to this heritage. At each step, <A
HREF="mud.html#KeepItWorking">KEEPING IT WORKING</A> is a premiere
consideration in deciding whether to extend or enhance the system.
Both systems might be good candidates for <A
HREF="mud.html#Reconstruction">RECONSTRUCTION</A>, were the
resources, interest, and audience present to justify such an
undertaking. In the mean time, these systems, which are still
sufficiently well suited to the particular tasks for which they were
built, remain in service. Keeping them on the air takes far less
energy than rewriting them. They continue to evolve, in a <A
HREF="mud.html#PiecemealGrowth">PIECEMEAL</A> fashion, a little at a
time.
</p>
<p>You can ameloriate the architectural erosion that can be caused
by quick-and-dirty code by isolating it from other parts of your
system, in its own objects, packages, or modules. To the extent that
such code can be quarantined, its ability to affect the integrity of
healthy parts of a system is reduced.</p>
<p>
Once it becomes evident that a purportedly disposable artifact is
going to be around for a while, one can turn one's attention to
improving its structure, either through an iterative process of <A
HREF="mud.html#PiecemealGrowth">PIECEMEAL GROWTH</A>, or via a fresh
draft, as discussed in the <A HREF="mud.html#Reconstruction">RECONSTRUCTION</A>
pattern.
</p>
<p align="center">
<A HREF="http://www.truelink.net/user/cliffymel/dvalley.htm"> <IMG
SRC="../images/pictures/rhyolite-small.jpg" hspace=10 ALT="Rhyolite"></A>
</p>
<P ALIGN="CENTER">
<font face="Courier New" size=2> From <I>boomtown</I> to <I>ghost
town</I>:<BR> The mining town of <B>Rhyolite</B>, in Death Valley,
was briefly the third largest city in Nevada.<BR> Then the ore
ran out.
</font>
</p>
<p> </p>
<A NAME="PiecemealGrowth"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px"><p
align="center">
<font color="#FFFFFF" size="5"><b>PIECEMEAL GROWTH</b></font></td>
</tr>
</table>
<table border="0" width="100%" bgcolor="#FFFF00" cellspacing="0"
cellpadding="0">
<tr>
<td width="100%" align="center"><i>alias</i></td>
</tr>
<tr>
<td width="100%" align="center">URBAN SPRAWL</td>
</tr>
<tr>
<td width="100%" align="center">ITERATIVE-INCREMENTAL
DEVELOPMENT</td>
</tr>
</table>
<p> </p>
<p align="center">
<font><A
HREF="http://liftoff.msfc.nasa.gov/RealTime/JTrack/Spacecraft.html">
<img src="../images/pictures/Mir-Mud.gif" width="385" height="250"
alt="Mir Complex">
</A></font>
</p>
<p>
<font face="Courier New" size=2> The Russian <A
HREF="http://www.maximov.com/Mir/">Mir ("Peace") Space Station</A>
Complex was <A HREF="http://www.maximov.com/Mir/mirdesign.html">designed</A>
for reconfiguration and <A
HREF="http://www.spaceviews.com/features/mir/display/index.html">modular
growth</A>. The Core module was launched in 1986, and the Kvant
("Quantum") and Kvant-2 modules joined the complex in 1987 and 1989.
The Kristall ("Crystal") module was added in 1990. The Spektr
("Spectrum") and shuttle Docking modules were added in 1995, the
latter surely a <A HREF="http://shuttle-mir.nasa.gov/">development</A>
not anticipated in 1986. The station’s final module, Priroda
("Nature"), was launched in 1996. The common core and independent
maneuvering capabilities of several of the modules have allowed the
complex to be <A HREF="http://www.hq.nasa.gov/osf/mir/">rearranged</A>
several times as it has grown.
</font>
</p>
<A
HREF="http://www.sigs.com/publications/docs/objm/9704/9704.booch.html">
<IMG SRC="../images/pictures/sprawl-small.jpg"
ALT="Urban Sprawl in Colorado" width=329 height=235 hspace=10
align="right">
</A>
<p>
Urban planning has an <A
HREF="http://www.architectureweek.com/2001/0822/culture_1-2.html">uneven</A>
history of success. For instance, Washington D.C. was laid out
according to a <A HREF="http://www.nbm.org/Capital/">master plan</A>
designed by the French architect <A
HREF="http://www.nps.gov/nama/lenfant.htm">L’Enfant</A>. The
capitals of
<!-- Was: http://www1.estado.com.br/english/brasil/brasili2.html -->
Brazil (<A
HREF="http://www.macalstr.edu/~geograph/world-urbanization/jmoersch/geography.html">Brasilia</A>)
and Nigeria (<A
HREF="http://cityguide.lycos.com/africa/westcentral_africa/NGAAbuja.html">Abuja</A>)
started as paper cities as well. Other cities, such as <a
href="http://www.patternlanguage.com/leveltwo/archivesframe.htm?/leveltwo/../archives/alexander1.htm">Houston</a>,
have grown without any overarching plan to guide them. Each approach
has its problems. For instance, the radial street plans in
L’Enftant’s master plan become awkward past a certain
distance from the center. The lack of any plan at all, on the other
hand, leads to a patchwork of residential, commercial, and industrial
areas that is dictated by the capricious interaction of local forces
such as land ownership, capital, and zoning. Since concerns such as
recreation, shopping close to homes, and noise and pollution away from
homes are not brought directly into the mix, they are not adequately
addressed.
</p>
<p>Most cities are more like Houston than Abuja. They may begin as
settlements, subdivisions, docks, or railway stops. Maybe people were
drawn by gold, or lumber, access to transportation, or empty land. As
time goes on, certain settlements achieve a critical mass, and a
positive feedback cycle ensues. The city’s success draws
tradesmen, merchants, doctors, and clergymen. The growing population
is able to support infrastructure, governmental institutions, and
police protection. These, in turn, draw more people. Different
sections of town develop distinct identities. With few exceptions,
(Salt Lake City comes to mind) the founders of these settlements never
stopped to think that they were founding major cities. Their ambitions
were usually more modest, and immediate.</p>
<P ALIGN="CENTER">
<!-- Also at: http://civila.com/brasilia/minis_ic.htm -->
<A HREF="http://www.geocities.com/~augusto_areal/minis_ic.htm"> <IMG
SRC="../images/pictures/brasilia09.jpg" ALT="Brasilia" hspace=10>
</A>
</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>It has become fashionable over the last several years to take
pot shots at the "traditional" waterfall process model. It may seem to
the reader that attacking it is tantamount to flogging a dead horse.
However, if it be a dead horse, it is a tenacious one. While the
approach itself is seen by many as having been long since discredited,
it has spawned a legacy of rigid, top-down, front-loaded processes and
methodologies that endure, in various guises, to this day. We can do
worse that examine the forces that led to its original development.</p>
<p>
In the days before waterfall development, programming pioneers
employed a simple, casual, relatively undisciplined "code-and-fix"
approach to software development. Given the primitive nature of the
problems of the day, this approach was frequently effective. However,
the result of this lack of discipline was, all too often, a <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A>.
</p>
<p>The waterfall approach arose in response to this muddy morass.
While the code-and-fix approach might have been suitable for small
jobs, it did not scale well. As software became more complex, it would
not do to simply gather a room full of programmers together and tell
them to go forth and code. Larger projects demanded better planning
and coordination. Why, it was asked, can't software be engineered like
cars and bridges, with a careful analysis of the problem, and a
detailed up-front design prior to implementation? Indeed, an
examination of software development costs showed that problems were
many times more expensive to fix during maintenance than during
design. Surely it was best to mobilize resources and talent up-front,
so as to avoid maintenance expenses down the road. It's surely wiser
to route the plumbing correctly now, before the walls are up, than to
tear holes in them later. Measure twice, cut once.</p>
<p>One of the reasons that the waterfall approach was able to
flourish a generation ago was that computers and business requirements
changed at a more leisurely pace. Hardware was very expensive, often
dwarfing the salaries of the programmers hired to tend it. User
interfaces were primitive by today's standards. You could have any
user interface you wanted, as long as it was an alphanumeric "green
screen". Another reason for the popularity of the waterfall approach
was that it exhibited a comfortable similarity to practices in more
mature engineering and manufacturing disciplines.</p>
<p>Today's designers are confronted with a broad onslaught of
changing requirements. It arises in part from the rapid growth of
technology itself, and partially from rapid changes in the business
climate (some of which is driven by technology). Customers are used to
more sophisticated software these days, and demand more choice and
flexibility. Products that were once built from the ground up by
in-house programmers must now be integrated with third-party code and
applications. User interfaces are complex, both externally and
internally. Indeed, we often dedicate an entire tier of our system to
their care and feeding. Change threatens to outpace our ability to
cope with it.</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><font><b>Master plans are often
rigid, misguided and out of date. Users’ needs change with
time.</b></font></td>
</tr>
</table>
<p>
<I>Change:</I> The fundamental problem with top-down design is that
real world requirement are inevitably moving targets. You can't simply
aspire to solve the problem at hand once and for all, because, by the
time you're done, the problem will have changed out from underneath
you. You can't simply do what the customer wants, for quite often,
they don't know what they want. You can't simply plan, you have to
plan to be able to adapt. If you can't fully anticipate what is going
to happen, you must be prepared to be nimble.
</p>
<p>
<I>Aesthetics:</I> The goal of up-front design is to be able to
discern and specify the significant architectural elements of a system
before ground is broken for it. A superior design, given this mindset,
is one that elegantly and completely specifies the system's structure
before a single line of code has been written. Mismatches between
these blueprints and reality are considered aberrations, and are
treated as mistakes on the part of the designer. A better design would
have anticipated these oversights. In the presence of volatile
requirements, aspirations towards such design perfection are as vain
as the desire for a hole-in-one on every hole.
</p>
<p>To avoid such embarrassment, the designer may attempt to cover
him or herself by specifying a more complicated, and more general
solution to certain problems, secure in the knowledge that others will
bear the burden of constructing these artifacts. When such predictions
about where complexity is needed are correct, they can indeed be a
source of power and satisfaction. This is part of their allure of
Venustas. However, sometime the anticipated contingencies never arise,
and the designer and implementers wind up having wasted effort solving
a problem that no one has ever actually had. Other times, not only is
the anticipated problem never encountered, its solution introduces
complexity in a part of the system that turns out to need to evolve in
another direction. In such cases, speculative complexity can be an
unnecessary obstacle to subsequent adaptation. It is ironic that the
impulse towards elegance can be an unintended source of complexity and
clutter instead.</p>
<p>In its most virulent form, the desire to anticipate and head off
change can lead to "analysis paralysis", as the thickening web of
imagined contingencies grows to the point where the design space seems
irreconcilably constrained.</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><b><u><i>Therefore</i></u>, incrementally
address forces that encourage change and growth. Allow
opportunities for growth to be exploited <u>locally</u>, as they
occur. Refactor unrelentingly.</b></td>
</tr>
</table>
<p>
Successful software attracts a wider audience, which can, in turn,
place a broader range of requirements on it. These new requirements
can run against the grain of the original design. Nonetheless, they
can frequently be addressed, but at the cost of cutting across the
grain of existing architectural assumptions. [Foote 1988] called this
architectural erosion <i><a
href="../dfc/discussion.html#Specificity">midlife generality loss</a></i>.
</p>
<p>
When designers are faced with a choice between building something
elegant from the ground up, or undermining the architecture of the
existing system to quickly address a problem, architecture usually
loses. Indeed, this is a natural phase in a system’s evolution [<A
HREF="../lifecycle/lifecycle.html">Foote & Opdyke 1995</A>]. This
might be thought of as <i>messy kitchen</i> phase, during which pieces
of the system are scattered across the counter, awaiting an eventual
cleanup. The danger is that the clean up is never done. With real
kitchens, the board of health will eventually intervene. With
software, alas, there is seldom any corresponding agency to police
such squalor. Uncontrolled growth can ultimately be a malignant force.
The result of neglecting to contain it can be a <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A>.
</p>
<p>
In <i>How Buildings Learn</i>, Brand [Brand 1994] observed that what
he called <i>High Road</i> architecture often resulted in buildings
that were expensive and difficult to change, while vernacular, <i>Low
Road</i> buildings like bungalows and warehouses were, paradoxically,
much more adaptable. Brand noted that <i>Function melts form</i>, and
low road buildings are more amenable to such change. Similarly, with
software, you may be reluctant to desecrate another programmer’s
cathedral. Expedient changes to a low road system that exhibits no
discernable architectural pretensions to begin with are easier to
rationalize.
</p>
<p>
In the Oregon Experiment [Brand 1994][Alexander 1988] <A
HREF="http://gee.cs.oswego.edu/dl/ca/ca/ca.html">Alexander</A> noted:
</p>
<dir>
<i> Large-lump development is based on the idea of <b>replacement</b>.
Piecemeal Growth is based on the idea of <b>repair</b>. …
Large-lump development is based on the fallacy that it is possible to
build perfect buildings. Piecemeal growth is based on the healthier
and more realistic view that mistakes are inevitable. … Unless
money is available for repairing these mistakes, every building, once
built, is condemned to be, to some extent unworkable. …
Piecemeal growth is based on the assumption that adaptation between
buildings and their users is necessarily a slow and continuous
business which cannot, under any circumstances, be achieve in a
single leap.
</i>
</dir>
<p>Alexander has noted that our mortgage and capital expenditure
policies make large sums of money available up front, but do nothing
to provide resources for maintenance, improvement, and evolution
[Brand 1994][Alexander 1988]. In the software world, we deploy our
most skilled, experienced people early in the lifecycle. Later on,
maintenance is relegated to junior staff, when resources can be
scarce. The so-called maintenance phase is the part of the lifecycle
in which the price of the fiction of master planning is really paid.
It is maintenance programmers who are called upon to bear the burden
of coping with the ever widening divergence between fixed designs and
a continuously changing world. If the hypothesis that architectural
insight emerges late in the lifecycle is correct, then this practice
should be reconsidered.</p>
<p>
Brand went on to observe <i>Maintenance <b>is</b> learning.
</i>He distinguishes three levels of learning in the context of systems.
This first is habit, where a system dutifully serves its function
within the parameters for which it was designed. The second level
comes into play when the system must adapt to change. Here, it usually
must be modified, and its capacity to sustain such modification
determines it’s degree of adaptability. The third level is the
most interesting: <i>learning to learn</i>. With buildings, adding a
raised floor is an example. Having had to sustain a major upheaval,
the system adapts so that subsequent adaptations will be much less
painful.
</p>
<p>
<A HREF="mud.html#PiecemealGrowth">PIECEMEAL GROWTH</A> can be
undertaken in an opportunistic fashion, starting with the existing,
living, breathing system, and working outward, a step at a time, in
such a way as to not undermine the system’s viability. You
enhance the program as you use it. Broad advances on all fronts are
avoided. Instead, change is broken down into small, manageable chunks.
</p>
<p>
One of the most striking things about <A
HREF="mud.html#PiecemealGrowth">PIECEMEAL GROWTH</A> is the role
played by <I>Feedback</I>. Herbert Simon [Simon 1969] has observed
that few of the adaptive systems that have been forged by evolution or
shaped by man depend on prediction as their main means of coping with
the future. He notes that two complementary mechanisms, homeostasis,
and retrospective feedback, are often far more effective. Homeostasis
insulates the system from short-range fluctuations in its environment,
while feedback mechanisms respond to long-term discrepancies between a
system's actual and desired behavior, and adjust it accordingly.
Alexander [Alexander 1964] has written extensively of the roles that
homeostasis and feedback play in adaptation as well.
</p>
<p>
If you can adapt quickly to change, predicting it becomes far less
crucial. Hindsight, as Brand observes [Brand 1994] is better than
foresight. Such rapid adaptation is the basis of one of the mantras of
<A HREF="http://www.xprogramming.com">Extreme Programming</A> [Beck
2000]: <I>You're not going to need it</I>.
</p>
<p>Proponents of XP (as it is called) say to pretend you are not a
smart as you think you are, and wait until this clever idea of yours
is actually required before you take the time to bring it into being.
In the cases where you were right, hey, you saw it coming, and you
know what to do. In the cases where you were wrong, you won't have
wasted any effort solving a problem you've never had when the design
heads in an unanticipated direction instead.</p>
<p>
<A HREF="http://www.xprogramming.com">Extreme Programming</A> relies
heavily on feedback to keep requirements in sync with code, by
emphasizing short (three week) iterations, and extensive, continuous
consultation with users regarding design and development priorities
throughout the development process. Extreme Programmers do not engage
in extensive up-front planning. Instead, they produce working code as
quickly as possible, and steer these prototypes towards what the users
are looking for based on feedback.
</p>
<p>Feedback also plays a role in determining coding assignments.
Coders who miss a deadline are assigned a different task during the
next iteration, regardless of how close they may have been to
completing the task. This form of feedback resembles the stern justice
meted out by the jungle to the fruit of uncompetitive pairings.</p>
<p>
<A HREF="http://www.xprogramming.com">Extreme Programming</A> also
emphasizes testing as an integral part of the development process.
Tests are developed, ideally, before the code itself. Code is
continuously tested as it is developed.
</p>
<p>
There is a "back-to-the-future" quality to Extreme Programming. In
many respects, it resembles the blind <I>Code and Fix</I> approach.
The thing that distinguishes it is the central role played by feedback
in driving the system's evolution. This evolution is abetted, in turn,
by modern object-oriented languages and powerful refactoring tools.
</p>
<p>Proponents of extreme programming portray it as placing minimal
emphasis on planning and up-front design. They rely instead on
feedback and continuous integration. We believe that a certain amount
of up-front planning and design is not only important, but inevitable.
No one really goes into any project blindly. The groundwork must be
laid, the infrastructure must be decided upon, tools must be selected,
and a general direction must be set. A focus on a shared architectural
vision and strategy should be established early.</p>
<p>Unbridled, change can undermine structure. Orderly change can
enhance it. Change can engender malignant sprawl, or healthy, orderly
growth.</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>
A broad consensus that objects emerge from an <i>iterative
incremental</i> evolutionary process has formed in the object-oriented
community over the last decade. See for instance [Booch 1994]. The <A
HREF="../metamorphosis/metamorphosis.html#SoftwareTectonics">SOFTWARE
TECTONICS</A> pattern [Foote & Yoder 1996] examines how systems can
incrementally cope with change.
</p>
<p>
The biggest risk associated with <A HREF="mud.html#PiecemealGrowth">PIECEMEAL
GROWTH</A> is that it will gradually erode the overall structure of the
system, and inexorably turn it into a <A HREF="mud.html#BigBallOfMud">BIG
BALL OF MUD</A>. A strategy of <A HREF="mud.html#KeepItWorking">KEEPING
IT WORKING</A> goes hand in hand with <A HREF="mud.html#PiecemealGrowth">PIECEMEAL
GROWTH</A>. Both patterns emphasize acute, local concerns at the expense
of chronic, architectural ones.
</p>
<p>
To counteract these forces, a permanent commitment to <A
HREF="../lifecycle/lifecycle.html#Consolidate">CONSOLIDATION</A> and
<A HREF="../lifecycle/lifecycle.html#Table2">refactoring</A> must be
made. It is through such a process that local and global forces are
reconciled over time. This lifecyle perspective has been dubbed the <i><A
HREF="../frameworks/fractal.html">fractal model</A></i> [<A
HREF="../lifecycle/lifecycle.html">Foote & Opdyke 1995</A>]. To
quote Alexander [Brand 1994][Alexander 1988]:
</p>
<dir>
<i>An organic process of growth and repair must create a gradual
sequence of changes, and these changes must be distributed evenly
across all levels of scale. [In developing a college campus] there
must be as much attention to the repair of details—rooms, wings
of buildings, windows, paths—as to the creation of brand new
buildings. Only then can the environment be balanced both as a whole,
and in its parts, at every moment in its history.</i>
</dir>
<p> </p>
<A NAME="KeepItWorking"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px">
<p align="CENTER">
<b><font size="5" color="#ffffff">KEEP IT WORKING</font></b>
</td>
</tr>
</table>
<table border="0" width="100%" bgcolor="#FFFF00" cellspacing="0"
cellpadding="0">
<tr>
<td width="100%" align="center"><i>alias</i></td>
</tr>
<tr>
<td width="100%" align="center">VITALITY</td>
</tr>
<tr>
<td width="100%" align="center">BABY STEPS</td>
</tr>
<tr>
<td width="100%" align="center">DAILY BUILD</td>
</tr>
<tr>
<td width="100%" align="center">FIRST, DO NO HARM</td>
</tr>
</table>
<p>
<font face="Courier New" size=2>Probably the greatest factor
that keeps us moving forward is that we use the system all the time,
and we keep trying to do new things with it. It is this
"living-with" which drives us to root out failures, to
clean up inconsistencies, and which inspires our occasional
innovation.</font>
</p>
<p>
<font face="Courier New" size=2><b>Daniel H. H. Ingalls </b>[Ingalls
1983]</font>
</p>
<A HREF="http://kpt1.tricon.net/Personal/wesley/primum.html"> <img
src="../images/pictures/hippocrates.jpg" hspace="10"
alt="First, Do No Harm" ALIGN="RIGHT"></A>
<p>Once a city establishes its infrastructure, it is imperative
that it be kept working. For example, if the sewers break, and
aren’t quickly repaired, the consequences can escalate from
merely unpleasant to genuinely life threatening. People come to expect
that they can rely on their public utilities being available 24 hours
per day. They (rightfully) expect to be able to demand that an outage
be treated as an emergency.</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>Software can be like this. Often a business becomes dependent
upon the data driving it. Businesses have become critically dependent
on their software and computing infrastructures. There are numerous
mission critical systems that must be on-the-air twenty-four hours a
day/seven days per week. If these systems go down, inventories can not
be checked, employees can not be paid, aircraft cannot be routed, and
so on.</p>
<p>
There may be times where taking a system down for a major overhaul can
be justified, but usually, doing so is fraught with peril. However,
once the system is brought back up, it is difficult to tell which from
among a large collection of modifications might have caused a new
problem. Every change is suspect. This is why deferring such
integration is a recipe for misery. Capers Jones [Jones 1999] reported
that the chance that a significant change might contain a new error--a
phenomenon he ominously referred to as a <I>Bad Fix Injection</I>--
was about 7% in the United States. This may strike some readers as a
low figure. Still, it's easy to see that compounding this possibility
can lead to a situation where multiple upgrades are increasing likely
to break a system.
</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><b>Maintenance needs have accumulated, but
an overhaul is unwise, since you might break the system.</b></td>
</tr>
</table>
<p>
<I>Workmanship:</I> Architects who live in the house they are building
have an obvious incentive to insure that things are done properly,
since they will directly reap the consequences when they do not. The
idea of the architect-builder is a central theme of Alexander's work.
Who better to resolve the forces impinging upon each design issue as
it arises as the person who is going to have to live with these
decisions? The architect-builder will be the direct beneficiary of his
or her own workmanship and care. Mistakes and shortcuts will merely
foul his or her own nest.
</p>
<p>
<I>Dependability:</I> These days, people rely on our software
artifacts for their very livelihoods, and even, at time, for their
very safety. It is imperative that ill-advise changes to elements of a
system do not drag the entire system down. Modern software systems are
intricate, elaborate webs of interdependent elements. When an
essential element is broken, everyone who depends on it will be
affected. Deadlines can be missed, and tempers can flare. This problem
is particularly acute in <A HREF="mud.html#BigBallOfMud">BIG BALLS
OF MUD</A>, since a single failure can bring the entire system down like
a house of cards.
</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><b><u><i>Therefore</i></u>, do what it
takes to maintain the software and keep it going. Keep it working.</b></td>
</tr>
</table>
<p>When you are living in the system youre building, you have an
acute incentive not to break anything. A plumbing outage will be a
direct inconvenience, and hence you have a powerful reason to keep it
brief. You are, at times, working with live wires, and must exhibit
particular care. A major benefit of working with a live system is that
feedback is direct, and nearly immediate.</p>
<p>
One of the strengths of this strategy is that modifications that break
the system are rejected immediately. There are always a large number
of paths forward from any point in a system’s evolution, and most
of them lead nowhere. By immediately selecting only those that do <u>not</u>
undermine the system’s viability, obvious dead-ends are avoided.
</p>
<p>
Of course, this sort of reactive approach, that of kicking the
nearest, meanest woolf from your door, is not necessarily globally
optimal. Yet, by eliminating obvious wrong turns, <u>only</u> more
insidiously incorrect paths remain. While these are always harder to
identify and correct, they are, fortunately less numerous than those
cases where the best immediate choice is also the best overall choice
as well.
</p>
<p>It may seem that this approach only accommodates minor
modifications. This is not necessarily so. Large new subsystems might
be constructed off to the side, perhaps by separate teams, and
integrated with the running system in such a way as to minimize
distruption.</p>
<p>Design space might be thought of as a vast, dark, largely
unexplored forest. Useful potential paths through it might be thought
of as encompassing working programs. The space off to the sides of
these paths is much larger realm of non-working programs. From any
given point, a few small steps in most directions take you from a
working to a non-working program. From time to time, there are forks
in the path, indicating a choice among working alternatives. In
unexplored territory, the prudent strategy is never to stray too far
from the path. Now, if one has a map, a shortcut through the trekless
thicket that might save miles may be evident. Of course, pioneers, by
definition, don’t have maps. By taking small steps in any
direction, they know that it is never more than a few steps back to a
working system.</p>
<p ALIGN=CENTER>
<font face="Courier New" size=2>Some years ago, Harlan Mills
proposed that any software system should be grown by incremental
development. That is, the system first be made to run, even though it
does nothing useful except call the proper set of dummy subprograms.
Then, bit by bit, it is fleshed out, with the subprograms in turn
being developed into actions or calls to empty stubs in the level
below.</font>
</p>
<p ALIGN=CENTER>
<font face="Courier New" size=2>…</font>
</p>
<p ALIGN=CENTER>
<font face="Courier New" size=2>Nothing in the past decade has
so radically changed my own practice, and its effectiveness.</font>
</p>
<p ALIGN=CENTER>
<font face="Courier New" size=2>…</font>
</p>
<p ALIGN=CENTER>
<font face="Courier New" size=2>One always has, at every stage,
in the process, a working system. I find that teams can <i>grow</i>
much more complex entities in four months than they can <i>build.</i>
</font>
</p>
<p>
<font face="Courier New" size=2>-- From "<i>No Silver
Bullet" </i>[Brooks 1995]
</font>
</p>
<p>Microsoft mandates that a DAILY BUILD of each product be
performed at the end of each working day. Nortel adheres to the
slightly less demanding requirement that a working build be generated
at the end of each week [Brooks 1995][Cusumano & Shelby 1995].
Indeed, this approach, and keeping the last working version around,
are nearly universal practices among successful maintenance
programmers.</p>
<p>Another vital factor in ensuring a system's continued vitality
is a commitment to rigorous testing [Marick 1995][Bach 1994]. It's
hard to keep a system working if you don't have a way of making sure
it works. Testing is one of pillars of Extreme Programming. XP
practices call for the development of unit tests before a single line
of code is written.</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>
Always beginning with a working system helps to encourage <A
HREF="mud.html#PiecemealGrowth">PIECEMEAL GROWTH</A>. Refactoring is
the primary means by which programmers maintain order from inside the
systems in which they are working. The goal of refactoring is to leave
a system working as well after a refactoring as it was before the
refactoring. Aggressive unit and integration testing can help to
guarantee that this goal is met.
</p>
<p> </p>
<A NAME="ShearingLayers"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px"><p
align="CENTER">
<b><font size="5" color="#ffffff">SHEARING LAYERS</font></b>
</p></td>
</tr>
</table>
<!--
<table border="0" width="100%" bgcolor="#FFFF00" cellspacing="0" cellpadding="0">
<tr>
<td width="100%" align="center"><i>alias</i></td>
<b>
</tr>
<tr>
</b><td width="100%" align="center">POTEMKIN VILLAGE</td>
<b>
</tr>
<tr>
</b><td width="100%" align="center">HOUSECLEANING </td>
<b>
</tr>
<tr>
</b><td width="100%" align="center">PRETTY FACE</td>
<b>
</tr>
<tr>
</b><td width="100%" align="center">QUARANTINE</td>
<b>
</tr>
<tr>
</b><td width="100%" align="center">HIDING IT UNDER THE BED</td>
<b>
</tr>
</table>
</b>
-->
<P ALIGN="CENTER">
<A HREF="http://www.corbis.com"> <IMG
SRC="../images/pictures/hummingbird.jpg" ALT="Hummingbird">
</A>
</p>
<p align="center">
<font face="Courier New" size=2>Hummingbirds and flowers are
quick, redwood trees are slow, and whole redwood forests are even
slower. Most interaction is within the same pace level--hummingbirds
and flowers pay attention to each other, oblivious to redwoods, who
are oblivious to them.</font>
</p>
<p align="center">
<font face="Courier New" size=2><b>R. V. O'Neill </b>, <I>A
Hierarchical Concept of Ecosystems</I></font>
</p>
<p>
The notion of <A HREF="mud.html#ShearingLayers">SHEARING LAYERS</A> is
one of the centerpieces of Brand's <I>How Buildings Learn</I> [Brand
1994]. Brand, in turn synthesized his ideas from a variety of sources,
including British designer Frank Duffy, and ecologist R. V. O'Neill.
</p>
<A HREF="../images/figures/shearing-layers.gif"> <IMG
SRC="../images/figures/shearing-small.gif" ALIGN="RIGHT" HSPACE="10"
VSPACE="10" BORDER="0" ALT="Brand, Page 13">
</A>
<p>Brand quotes Duffy as saying: "Our basic argument is that there
isn't any such thing as a building. A building properly conceived is
several layers of longevity of built components".</p>
<p>Brand distilled Duffy's proposed layers into these six: Site,
Structure, Skin, Services, Space Plan, and Stuff. Site is geographical
setting. Structure is the load bearing elements, such as the
foundation and skeleton. Skin is the exterior surface, such as siding
and windows. Services are the circulatory and nervous systems of a
building, such as its heating plant, wiring, and plumbing. The Space
Plan includes walls, flooring, and ceilings. Stuff includes lamps,
chairs, appliances, bulletin boards, and paintings.</p>
<p>These layers change at different rates. Site, they say, is
eternal. Structure may last from 30 to 300 years. Skin lasts for
around 20 years, as it responds to the elements, and to the whims of
fashion. Services succumb to wear and technical obsolescence more
quickly, in 7 to 15 years. Commercial Space Plans may turn over every
3 years. Stuff, is, of course, subject to unrelenting flux [Brand
1994].</p>
<!--
<P ALIGN="CENTER">
<IMG src="../images/figures/shearing-layers.gif"
ALT="Brand, Page 13">
</p>
-->
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>
Software systems cannot stand still. Software is often called upon to
bear the brunt of changing requirements, because, being as that it is
made of bits, it <u>can</u> change.
</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><font><b>Different artifacts change
at different rates.</b></font></td>
</tr>
</table>
<p>
<I>Adaptability:</I> A system that can cope readily with a wide range
of requirements, will, all other things being equal, have an advantage
over one that cannot. Such a system can allow unexpected requirements
to be met with little or no reengineering, and allow its more skilled
customers to rapidly address novel challenges.
</p>
<p>
<I>Stability:</I> Systems succeed by doing what they were designed to
do as well as they can do it. They earn their niches, by bettering
their competition along one or more dimensions such as cost, quality,
features, and performance. See [<A HREF="../lingua/lingua.html">Foote
& Roberts 1998</A>] for a discussion of the occasionally fickle nature of
such completion. Once they have found their niche, for whatever
reason, it is essential that short term concerns not be allowed to
wash away the elements of the system that account for their mastery of
their niche. Such victories are inevitably hard won, and fruits of
such victories should not be squandered. Those parts of the system
that do what the system does well must be protected from fads, whims,
and other such spasms of poor judgement.
</p>
<p>
<I>Adaptability</I> and <I>Stability</I> are forces that are in
constant tension. On one hand, systems must be able to confront
novelty without blinking. On the other, they should not squander their
patrimony on spur of the moment misadventures.
</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><b><u><i>Therefore</i></u>, factor your
system so that artifacts that change at similar rates are together.</b></td>
</tr>
</table>
<p>
Most interactions in a system tend to be within layers, or between
adjacent layers. Individual layers tend to be about things that change
at similar rates. Things that change at different rates diverge.
Differential rates of change encourage layers to emerge. Brand notes
as well that occupational specialties emerge along with these layers.
The rate at which things change shapes our organizations as well. For
instance, decorators and painters concern themselves with interiors,
while architects dwell on site and skin. We expect to see things that
evolve at different rates emerge as distinct concerns. This is <A
HREF="http://st-www.cs.uiuc.edu/~droberts/evolve.html#SeparateChangeable">"separate
that which changes from that which doesn't"</A> [<A
HREF="http://st-www.cs.uiuc.edu/~droberts/evolve.html">Roberts
& Johnson 1998</A>] writ large.
</p>
<p>Can we identify such layers in software?</p>
<p>Well, at the bottom, there are data. Things that change most
quickly migrate into the data, since this is the aspect of software
that is most amenable to change. Data, in turn, interact with users
themselves, who produce and consume them.</p>
<p>Code changes more slowly than data, and is the realm of
programmers, analysts and designers. In object-oriented languages,
things that will change quickly are cast as black-box polymorphic
components. Elements that will change less often may employ white-box
inheritance.</p>
<p>The abstract classes and components that constitute an
object-oriented framework change more slowly than the applications
that are built from them. Indeed, their role is to distill what is
common, and enduring, from among the applications that seeded the
framework.</p>
<p>
As frameworks evolve, certain abstractions make their ways from
individual applications into the frameworks and libraries that
constitute the system's infrastructure [<A
HREF="../dfc/discussion.html">Foote 1988</A>]. Not all elements will
make this journey. Not all should. Those that do are among the most
valuable legacies of the projects that spawn them. Objects help
shearing layers to emerge, because they provide places where more
fine-grained chunks of code and behavior that belong together can
coalesce.
</p>
<p>The Smalltalk programming language is built from a set of
objects that have proven themselves to be of particular value to
programmers. Languages change more slowly than frameworks. They are
the purview of scholars and standards committees. One of the
traditional functions of such bodies is to ensure that languages
evolve at a suitably deliberate pace.</p>
<p>Artifacts that evolve quickly provide a system with dynamism and
flexibility. They allow a system to be fast on its feet in the face of
change.</p>
<p>Slowly evolving objects are bulwarks against change. They embody
the wisdom that the system has accrued in its prior interactions with
its environment. Like tenure, tradition, big corporations, and
conservative politics, they maintain what has worked. They worked
once, so they are kept around. They had a good idea once, so maybe
they are a better than even bet to have another one.</p>
<p>Wide acceptance and deployment causes resistance to change. If
changing something will break a lot of code, there is considerable
incentive not to change it. For example, schema reorganization in
large enterprise databases can be an expensive and time-consuming
process. Database designers and administrators learn to resist change
for this reason. Separate job descriptions, and separate hardware,
together with distinct tiers, help to make these tiers distinct.</p>
<p>The phenomenon whereby distinct concerns emerge as distinct
layers and tiers can be seen as well with graphical user interfaces.</p>
<p>
Part of the impetus behind using <A
HREF="../metadata/metadata.html#Metadata">METADATA</A> [<A
HREF="../metadata/metadata.html">Foote & Yoder 1998b</A>] is the
observation that pushing complexity and power into the data pushes
that same power (and complexity) out of the realm of the programmer
and into the realm of users themselves. Metadata are often used to
model static facilities such as classes and schemas, in order to allow
them to change dynamically. The effect is analogous to that seen with
modular office furniture, which allows office workers to easily,
quickly, and cheaply move partitions without having to enlist
architects and contractors in the effort.
</p>
<p>Over time, our frameworks, abstract classes, and components come
to embody what we've learned about the structure of the domains for
which they are built. More enduring insights gravitate towards the
primary structural elements of these systems. Things which find
themselves in flux are spun out into the data, where users can
interact with them. Software evolution becomes like a centrifuge spun
by change. The layers that result, over time, can come to a much truer
accommodation with the forces that shaped them than any top-down
agenda could have devised.</p>
<p align="center">
<font face="Courier New" size=2>Things that are good have a
certain kind of structure. You cant get that structure except
dynamically. Period. In nature youve got continuous
very-small-feedback-loop adaptation going on, which is why things get
to be harmonious. Thats why they have the qualities we value. If it
wasnt for the time dimension, it wouldnt happen. Yet here we are
playing the major role creating the world, and we havent figured
this out. That is a very serious matter.</font>
</p>
<p align="center">
<font face="Courier New" size=2><b>Christopher Alexander</b> --
[Brand 1994]</font>
</p>
<P ALIGN="CENTER">
<A HREF="http://sregora.com/gallery/cagallery.html"> <IMG
SRC="../images/pictures/redwood.jpg" ALT="Redwood">
</A>
</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>
This pattern has much in common with the <A
HREF="http://st-www.cs.uiuc.edu/~droberts/evolve.html#SeparateChangeable">HOT
SPOTS</A> pattern discussed in [<A
HREF="http://st-www.cs.uiuc.edu/~droberts/evolve.html">Roberts
& Johnson 1998</A>]. Indeed, separating things that change from those
that do not is what drives the emergence of <A
HREF="mud.html#ShearingLayers">SHEARING LAYERS</A>. These <A
HREF="http://www.rational.com/products/whitepapers/390.jsp#page=11">
layers</A> are the result of such differential rates of change, while <A
HREF="http://st-www.cs.uiuc.edu/~droberts/evolve.html#SeparateChangeable">HOT
SPOTS</A> might be thought of as the rupture zones in the fault lines
along which slippage between layers occurs. This tectonic slippage is
suggestive as well of the <A
HREF="../metamorphosis/metamorphosis.html#SoftwareTectonics">SOFTWARE
TECTONICS</A> pattern [<A HREF="../metamorphosis/metamorphosis.html">Foote
& Yoder 1996</A>], which recommends fine-grained iteration as a means
of avoiding catastrophic upheaval. <A
HREF="../metadata/metadata.html#Metadata">METADATA</A> and <A
HREF="../metadata/metadata.html#ActiveObjectModel">ACTIVE
OBJECT-MODELS</A> [<A HREF="../metadata/metadata.html">Foote &
Yoder 1998b</A>] allow systems to adapt more quickly to changing
requirements by <A
HREF="http://www.joeyoder.com/~yoder/Research/metadata/OOPSLA98MetaDataWkshop.html">pushing
power</A> into the data, and out onto users.
</p>
<p> </p>
<A NAME="SweepingItUnderTheRug"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px">
<p align="CENTER">
<font size="5" color="#ffffff"><b>SWEEPING IT UNDER THE
RUG</b></font>
</p>
</td>
</tr>
</table>
<table border="0" width="100%" bgcolor="#FFFF00" cellspacing="0"
cellpadding="0">
<tr>
<td width="100%" align="center"><i>alias</i></td>
</tr>
<tr>
<td width="100%" align="center">POTEMKIN VILLAGE</td>
</tr>
<tr>
<td width="100%" align="center">HOUSECLEANING</td>
</tr>
<tr>
<td width="100%" align="center">PRETTY FACE</td>
</tr>
<tr>
<td width="100%" align="center">QUARANTINE</td>
</tr>
<tr>
<td width="100%" align="center">HIDING IT UNDER THE BED</td>
</tr>
<tr>
<td width="100%" align="center">REHABILITATION</td>
</tr>
</table>
<p align="CENTER">
<A HREF="http://www.ic-chernobyl.kiev.ua/index.html"><img
src="../images/pictures/reactor4-shirley.gif" width="432"
height="282" alt="Concrete Sarcophagus"></A>
</p>
<p align="CENTER">
<font face="Courier New" size=2>One of the most spectacular
examples of <i>sweeping a problem under the rug</i> is the <!-- <A HREF="http://www.bbc.co.uk/horizon/95-96/960325.html">concrete sarcophagus</A> -->
concrete sarcophagus that Soviet engineers constructed to put a
10,000 year lid on the infamous <A
HREF="http://polyn.net.kiae.su/polyn/head_ill.html">reactor
number four</A> at <A
HREF="http://www.kingroach.com/comics/chernobyl.html">Chernobyl</A>,
in what is now Ukraine.
</font>
</p>
<p>If you can’t make a mess go away, at least you can hide it.
Urban renewal can begin by painting murals over graffiti and putting
fences around abandoned property. Children often learn that a single
heap in the closet is better than a scattered mess in the middle of
the floor.</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>There are reasons, other than aesthetic concerns, professional
pride, and guilt for trying to clean up messy code. A deadline may be
nearing, and a colleague may want to call a chunk of your code, if you
could only come up with an interface through which it could be called.
If you don’t come up with an easy to understand interface,
they’ll just use someone else’s (perhaps inferior) code. You
might be cowering during a code-review, as your peers trudge through a
particularly undistinguished example of your work. You know that there
are good ideas buried in there, but that if you don’t start to
make them more evident, they may be lost.</p>
<p>
There is a limit to how much chaos an individual can tolerate before
being overwhelmed. At first glance, a <A HREF="mud.html#BigBallOfMud">BIG
BALL OF MUD</A> can inspire terror and despair in the hearts of those who
would try to tame it. The first step on the road to architectural
integrity can be to identify the disordered parts of the system, and
isolate them from the rest of it. Once the problem areas are
identified and hemmed in, they can be gentrified using a divide and
conquer strategy.
</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><font><b>Overgrown, tangled,
haphazard spaghetti code is hard to comprehend, repair, or extend,
and tends to grow even worse if it is not somehow brought under
control.</b></font></td>
</tr>
</table>
<P ALIGN="CENTER">
<A HREF="http://www.jaffebros.com/lee/gulliver/prittie/cover.jpeg">
<IMG SRC="../images/pictures/threads-small.jpg"
ALT="The Bondage of Gulliver" ALIGN="RIGHT" HSPACE="10">
</A>
</p>
<p>
<I>Comprehensibility:</I> It should go without saying that
comprehensible, attractive, well-engineered code will be easier to
maintain and extend than complicated, convoluted code. However, it
takes <I>Time</I> and money to overhaul sloppy code. Still, the <I>Cost</I>
of allowing it to fester and continue to decline should not be
underestimated.
</p>
<p>
<I>Morale:</I> Indeed, the price of life with a <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A> goes beyond the
bottom line. Life in the muddy trenches can be a dispiriting fate.
Making even minor modifications can lead to maintenance marathons.
Programmers become timid, afraid that tugging at a loose thread may
have unpredictable consequences. After a while, the myriad <A
HREF="../images/pictures/gulliver-threads.jpg">threads</A> that
couple every part of the system to every other come to tie the
programmer down as surely as <A
HREF="http://www.jaffebros.com/lee/gulliver/">Gulliver</A> among the
<A HREF="http://www.jaffebros.com/lee/gulliver/bk1/index.html">Lilliputians</A>
[<A HREF="http://www.jaffebros.com/lee/gulliver/contents.html">Swift
1726</A>]. Talent may desert the project in the face of such bondage.
</p>
<!--
<P ALIGN="CENTER">
<A HREF="http://www.jaffebros.com/lee/gulliver/prittie/cover.jpeg">
<IMG src="../images/pictures/threads.jpg"
ALT="The Bondage of Gulliver">
</A>
</p>
-->
<p>It should go without saying that comprehensible, attractive,
well-engineered code will be easier to maintain and extend than
complicated, convoluted code. However, it takes time and money to
overhaul sloppy code. Still, the cost of allowing it to fester and
continue to decline should not be underestimated.</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><b><u><i>Therefore</i></u>, if you
can’t easily make a mess go away, at least cordon it off. This
restricts the disorder to a fixed area, keeps it out of sight, and
can set the stage for additional refactoring.</b></td>
</tr>
</table>
<p>By getting the dirt into a single pile beneath the carpet, you
at least know where it is, and can move it around. You’ve still
got a pile of dirt on your hands, but it is localized, and your guests
can’t see it. As the engineers who entombed reactor number four
at Chernobly demonstrated, sometimes you've got to get a lid on a
problem before you can get serious about cleaning things up. Once the
problem area is contained, you can decontaminate at a more leisurely
pace.</p>
<A
HREF="http://www.pathfinder.com/@@z04;c6PyNAIAQH2x/photo/archive/themes/urban.htm">
<IMG SRC="../images/pictures/urban-decay-small.jpg" ALIGN="LEFT"
HSPACE="10" VSPACE="10" ALT="Urban Decay">
</A>
<p>To begin to get a handle on spaghetti code, find those sections
of it that seem less tightly coupled, and start to draw architectural
boundaries there. Separate the global information into distinct data
structures, and enforce communication between these enclaves using
well-defined interfaces. Such steps can be the first ones on the road
to re-establishing the system’s conceptual integrity, and
discerning nascent architectural landmarks.</p>
<p>
Putting a fresh interface around a run down region of the system can
be the first step on the way architectural rehabilitation. This is a
long row to hoe, however. Distilling meaningful abstractions from a <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A> is a difficult and
demand task. It requires skill, insight, and persistence. At times, <A
HREF="mud.html#Reconstruction">RECONSTRUCTION</A> may seem like the
less painful course. Still, it is not like unscrambling an egg. As
with rehabilitation in the real world, restoring a system to
architectural health requires resources, as well as a sustained
commitment on the part of the people who live there.
</p>
<p>The UIMX user interface builder for Unix and Motif, and the
various Smalltalk GUI builders both provide a means for programmers to
cordon off complexity in this fashion.</p>
<!--
<P ALIGN="CENTER">
<A HREF="http://www.pathfinder.com/@@z04;c6PyNAIAQH2x/photo/archive/themes/urban.htm">
<IMG src="../images/pictures/urban-decay.jpg"
ALT="Urban Decay">
</A>
</p>
-->
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>
One frequently constructs a <A
HREF="http://ksi.cpsc.ucalgary.ca/~kremer/patterns/facade.html">FAÇADE</A>
[Gamma et. al. 1995] to put a <A
HREF="http://www.m-w.com/cgi-bin/dictionary?congenial">congenial</A>
"pretty face" on the unpleasantness that is <A
HREF="mud.html#SweepingItUnderTheRug">SWEPT UNDER THE RUG</A>. Once
these messy chunks of code have been quarantined, you can expose their
functionality using INTENTION REVEALING SELECTORS [Beck 1997].
</p>
<p>
This can be the first step on the road to <A
HREF="../lifecycle/lifecycle.html#Consolidate">CONSOLIDATION</A> too,
since one can begin to hem in unregulated growth than may have
occurred during <A HREF="../lifecycle/lifecycle.html#Prototype">PROTOTYPING</A>
or <A HREF="../lifecycle/lifecycle.html#Expand">EXPANSION</A> [<A
HREF="../lifecycle/lifecycle.html">Foote & Opdyke 1995</A>]. [<A
HREF="../selfish/selfish.html">Foote & Yoder 1998a</A>] explores
how, ironically, inscrutable code can persist <u>because</u> it is
difficult to comprehend.
</p>
<p>
This paper also examines how complexity can be hidden using suitable
defaults (<A HREF="../selfish/selfish.html#WorksOutOfTheBox">WORKS
OUT OF THE BOX</A> and <A
HREF="../selfish/selfish.html#ProgrammingByDifference">PROGRAMMING-BY-DIFFERRENCE</A>),
and interfaces that gradually reveal additional capabilities as the
client grows more sophisticated.
</p>
<p> </p>
<A NAME="Reconstruction"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px"><p
align="CENTER">
<font size="5" color="#ffffff"><b>RECONSTRUCTION</b></font>
</p></td>
</tr>
</table>
<table border="0" width="100%" bgcolor="#FFFF00" cellspacing="0"
cellpadding="0">
<tr>
<td width="100%" align="center"><i>alias</i></td>
</tr>
<tr>
<td width="100%" align="center">TOTAL REWRITE</td>
</tr>
<tr>
<td width="100%" align="center">DEMOLITION</td>
</tr>
<tr>
<td width="100%" align="center">THROWAWAY THE FIRST ONE</td>
</tr>
<tr>
<td width="100%" align="center">START OVER</td>
</tr>
</table>
<p align="CENTER">
<A HREF="../images/movies/fcs_demolition_26sec.mov"> <img
src="../images/pictures/atlanta/stadium.jpg" width="200" height="195"
alt="Fulton County Stadium Demolition"></A>
</p>
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<hr>
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<p>Atlanta’s Fulton County Stadium was built in 1966 to serve
as the home of baseball’s Atlanta Braves, and football’s
Atlanta Falcons. In August of 1997, the stadium was demolished. Two
factors contributed to its relatively rapid obsolescence. One was that
the architecture of the original stadium was incapable of
accommodating the addition of the "sky-box" suites that the
spreadsheets of ‘90s sporting economics demanded. No conceivable
retrofit could accommodate this requirement. Addressing it meant
starting over, from the ground up. The second was that the
stadium’s attempt to provide a cheap, general solution to the
problem of providing a forum for both baseball and football audiences
compromised the needs of both. In only thirty-one years, the balance
among these forces had shifted decidedly. The facility is being
replaced by two new single-purpose stadia.</p>
<p>Might there be lessons for us about unexpected requirements and
designing general components here?</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p align="center">
<font face="Courier New" size=2> <I>Plan to Throw One Away
(You Will Anyway)</I> -- Brooks
</font>
</p>
<p>Extreme Programming [Beck 2000] had its genesis in the Chrysler
Comprehensive Compensation project (C3). It began with a cry for help
from a foundering project, and a decision to discard a year and a
half's worth of work. The process they put in place after they started
anew laid the foundation for XP, and the author's credit these
approaches for the subsequent success of the C3 effort. However, less
emphasis is given to value of the experience the team might have
salvaged from their initial, unsuccessful draft. Could this first
draft have been the unsung hero of this tale?</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><font><b>Your code has declined to
the point where it is beyond repair, or even comprehension.</b></font></td>
</tr>
</table>
<p>
<i>Obsolescence</i>: Of course, one reason to abandon a system is that
it is in fact technically or economically obsolete. These are distinct
situations. A system that is no longer state-of-the-art may still sell
well, while a technically superior system may be overwhelmed by a more
popular competitor for non-technical reasons.
</p>
<p>In the realm of concrete and steel, blight is the symptom, and a
withdrawal of capital is the cause. Of course, once this process
begins, it can feed on itself. On the other hand, given a steady
infusion of resources, buildings can last indefinitely. It's not
merely entropy, but an unwillingness to counteract it, that allows
buildings to decline. In Europe, neighborhoods have flourished for
hundreds of years. They have avoided the boom/bust cycles that
characterize some New World cities.</p>
<p>
<i>Change:</i> Even though software is a highly malleable medium, like
Fulton County Stadium, new demands can, at times, cut across a
system’s architectural assumptions in such a ways as to make
accommodating them next to impossible. In such cases, a total rewrite
might be the only answer.
</p>
<p>
<i>Cost</i>: Writing-off a system can be traumatic, both to those who
have worked on it, and to those who have paid for it. Software is
often treated as an asset by accountants, and can be an expensive
asset at that. Rewriting a system, of course, does not discard its
conceptual design, or its staff’s experience. If it is truly the
case that the value of these assets is in the design experience they
embody, then accounting practices must recognize this.
</p>
<p>
<i>Organization:</i> Rebuilding a system from scratch is a
high-profile undertaking, that will demand considerable time and
resources, which, in turn, will make high-level management support
essential.
</p>
<table border="0" width="100%" cellpadding="0" cellspacing="0"
bgcolor="#FFFF00">
<tr>
<td width="100%"><b><u><i>Therefore</i></u>, throw it away
and start over.</b></td>
</tr>
</table>
<p>Sometimes it’s just easier to throw a system away, and
start over. Examples abound. Our shelves are littered with the
discarded carcasses of obsolete software and its documentation.
Starting over can be seen as a defeat at the hands of the old code, or
a victory over it.</p>
<A
HREF="http://www.sheridanc.on.ca/~randy/design.dir/disaster.dir/disaster.htm">
<IMG SRC="../images/pictures/pruitt3.jpg" ALT="Pruitt-Igoe"
ALIGN="RIGHT" HSPACE="10">
</A>
<p>One reason to start over might be that the previous system was
written by people who are long gone. Doing a rewrite provides new
personnel with a way to reestablish contact between the architecture
and the implementation. Sometimes the only way to understand a system
it is to write it yourself. Doing a fresh draft is a way to overcome
neglect. Issues are revisited. A fresh draft adds vigor. You draw back
to leap. The quagmire vanishes. The swamp is drained.</p>
<p>Another motivation for building a new system might be that you
feel that you've got the experience you need to do the job properly.
One way to have gotten this experience is to have participated at some
level in the unsuccessful development of a previous version of the
system.</p>
<p>Of course, the new system is not designed in a vacuum.
Brook’s famous tar pit is excavated, and the fossils are
examined, to see what they can tell the living. It is essential that a
thorough post-mortem review be done of the old system, to see what it
did well, and why it failed. Bad code can bog down a good design. A
good design can isolate and contain bad code.</p>
<p>
When a system becomes a <A HREF="mud.html#BigBallOfMud">BIG BALL
OF MUD</A>, its relative incomprehensibility may hasten its demise, by
making it difficult for it to adapt. It can persist, since it resists
change, but cannot evolve, for the same reason. Instead, its
inscrutability, even when it is to its s hort-term benefit, sows the
seeds of its ultimate demise.
</p>
<p>If this makes muddiness a frequently terminal condition, is this
really a bad thing? Or is it a blessing that these sclerotic systems
yield the stage to more agile successors? Certainly, the departure of
these ramshackle relics can be a cause for celebration as well as
sadness.</p>
<A HREF="http://www.webslingerz.com/~jhoffman/chcat.html"> <IMG
SRC="../images/pictures/chcat1.gif" ALT="Cheshire Cat" ALIGN="RIGHT">
</A>
<p>Discarding a system dispenses with its implementation, and
leaves only its conceptual design behind. Only the patterns that
underlie the system remain, grinning like a Cheshire cat. It is their
spirits that help to shape the next implementation. With luck, these
architectural insights will be reincarnated as genuine reusable
artifacts in the new system, such as abstract classes and frameworks.
It is by finding these architectural nuggets that the promise of
objects and reuse can finally be fulfilled.</p>
<p>
There are alternatives to throwning your system away and starting
over. One is to embark on a regimen of incremental refactoring, to
glean architectural elements and discernable abstractions from the
mire. Indeed, you can begin by looking for coarse fissures along which
to separate parts of the system, as was suggested in <A
HREF="mud.html#SweepingItUnderTheRug">SWEEPING IT UNDER THE RUG</A>.
Of course, refactoring is more effective as a prophylactic measure
that as a last-restort therapy. As with any edifice, it is a judgement
call, whether to rehab or restort for the wrecking ball. Another
alternative is to reassess whether new components and frameworks have
come along that can replace all or part of the system. When you can
reuse and retrofit other existing components, you can spare yourself
the time and expense involved in rebuilding, repairing, and
maintaining the one you have.
<p>
The United States Commerce Department defines <I>durable goods</I> as
those that are designed to last for three years or more. This category
traditionally applied to goods such as furniture, appliances,
automobiles, and business machines. Ironically, as computer equipment
is depreciating ever more quickly, it is increasingly our software
artifacts, and not our hardware, that fulfill this criterion. Firmitas
has come to the realm of bits and bytes.
</p>
Apple's Lisa Toolkit, and its successor, the Macintosh Toolbox,
constitute one of the more intriguing examples of
<p>
<A HREF="mud.html#Reconstruction">RECONSTRUCTION</A> in the history of
personal computing.
</p>
<p align="center">
<font face="Courier New" size=2> <I>An architect's most
useful tools are an eraser at the drafting board, and a wrecking bar
at the site</I> <BR>-- Frank Lloyd Wright
</font>
</p>
<p align="CENTER">
<font face="Wingdings">v</font><font> </font><font face="Wingdings">v</font><font>
</font><font face="Wingdings">v</font>
</p>
<p>
The <A HREF="../metamorphosis/metamorphosis.html#SoftwareTectonics">SOFTWARE
TECTONICS</A> pattern discussed in [Foote & Yoder 1996] observes that
if incremental change is deferred indefinitely, major upheaval may be
the only alternative. [Foote & Yoder 1998a] explores the <A
HREF="../selfish/selfish.html#WinningTeam">WINNING TEAM</A>
phenomenon, whereby otherwise superior technical solutions are
overwhelmed by non-technical <A
HREF="http://www.m-w.com/cgi-bin/dictionary?exigencies">exigencies</A>.
</p>
<p>
<A HREF="http://www.yourdon.com/books/coolbooks/notes/brooks.html">Brooks</A>
has eloquently observed that the most dangerous system an architect
will ever design is his or her <A
HREF="http://www.realtime-info.be/encyc/techno/terms/51/81.htm">second
system</A> [Brooks 1995]. This is the notorious <A
HREF="http://www.elsewhere.org/jargon_search/TAG1571.html">second-system
effect</A>. <A HREF="mud.html#Reconstruction">RECONSTRUCTION</A> provides
an opportunity for this misplaced hubris to exercise itself, so one
must keep a wary eye open for it. Still, there are times when the best
and only way to make a system better is to throw it away and start
over. Indeed, one can do worse than to heed Brook's classic admonition
that you should "plan to throw one away, you will anyway".
</p>
<p align="center">
<IMG SRC="../images/pictures/fiji.jpg" ALT="Mir over Fiji">
</p>
<p align="center">
<i>Mir reenters the atmosphere over Fiji on 22 March, 2001</i>
</p>
<!-- Pattern Header -->
<A NAME="Conclusion"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px">
<p align="center">
<font color="#FFFFFF" size="5"> <b>Conclusion</b>
</font>
</td>
</tr>
</table>
<!-- End of Pattern Header -->
<p>
In the end, software architecture is about how we distill experience
into wisdom, and disseminate it. We think the patterns herein stand
alongside other work regarding software architecture and evolution
that we cited as we went along. Still, we do not consider these
patterns to be anti-patterns. There are good reasons that good
programmers build <A HREF="mud.html#BigBallOfMud">BIG BALLS OF MUD</A>.
It may well be that the economics of the software world are such that
the market moves so fast that long term architectural ambitions are
foolhardy, and that expedient, slash-and-burn, disposable programming
is, in fact, a state-of-the-art strategy. The success of these
approaches, in any case, is undeniable, and seals their pattern-hood.
People build
<p>
<A HREF="mud.html#BigBallOfMud">BIG BALLS OF MUD</A> because they <U>work</U>.
In many domains, they are the only things that have been shown to
work. Indeed, they work where loftier approaches have yet to
demonstrate that they can compete.
</p>
<p>
It is not our purpose to condemn <A HREF="mud.html#BigBallOfMud">BIG
BALLS OF MUD</A>. Casual architecture is natural during the early stages
of a system’s evolution. The reader must surely suspect, however,
that our hope is that we can aspire to do better. By recognizing the
forces and pressures that lead to architectural malaise, and how and
when they might be confronted, we hope to set the stage for the
emergence of truly durable artifacts that can put architects in
dominant positions for years to come. The key is to ensure that the
system, its programmers, and, indeed the entire organization, <i>learn</i>
about the domain, and the architectural opportunities looming within
it, as the system grows and matures.
</p>
<p>
Periods of moderate disorder are a part of the ebb and flow of
software evolution. As a master chef tolerates a messy kitchen,
developers must not be afraid to get a little mud on their shoes as
they explore new territory for the first time. Architectural insight
is not the product of master plans, but of hard won experience. The
software architects of yesteryear had little choice other than to
apply the lessons they learned in successive drafts of their systems,
since <A HREF="mud.html#Reconstruction">RECONSTRUCTION</A> was often
the only practical means they had of supplanting a mediocre system
with a better one. Objects, frameworks, components, and refactoring
tools provide us with another alternative. Objects present a medium
for expressing our architectural ideas at a level between
coarse-grained applications and components and low level code.
Refactoring tools and techniques finally give us the means to
cultivate these artifacts as they evolve, and capture these insights.
</p>
<p>
The onion-domed <I>Church of the Intercession of the Virgin on the
Moat</I> in Moscow is one of Russia's most famous landmarks. It was built
by Tsar Ivan IV just outside of the Kremlin walls in 1552 to
commemorate Russia's victory over the Tatars at Kazan. The church is
better known by it's nickname, St. Basil's. Ivan too is better known
by his nickname "Ivan the Terrible". Legend has it that once the
cathedral was completed, Ivan, ever true to his reputation, had the
architects blinded, so that they could never build anything more
beautiful. Alas, the state of software architecture today is such that
few of us need fear for our eyesight.
</p>
<P ALIGN="CENTER">
<A
HREF="http://www.gac.edu/Academics/russian/www-docs/Architecture_HTML/page_id_6881.html">
<IMG SRC="../images/pictures/basils.jpg" ALT="St. Basil's" BORDER="0">
</A>
</p>
<!-- Pattern Header -->
<A NAME="Acknowledgments"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px">
<p align="center">
<font color="#FFFFFF" size="5"> <b>Acknowledgments</b>
</font>
</td>
</tr>
</table>
<!-- End of Pattern Header -->
<p>
A lot of people have striven to help us avoid turning this paper into
an unintentional example of its central theme. We are grateful first
of all to the members of the <a
href="http://st-www.cs.uiuc.edu/research-gp.html">University of
Illinois Software Architecture Group</A>, <A
HREF="http://st-www.cs.uiuc.edu/~brant">John Brant</A>, <A
HREF="http://st-www.cs.uiuc.edu/~chai">Ian Chai</A>, <A
HREF="http://st-www.cs.uiuc.edu/users/johnson/">Ralph Johnson</A>,
Lewis Muir, <A HREF="http://www.ncsa.uiuc.edu/people/daman/">Dragos
Manolescu</A>, <A HREF="http://www.stlabs.com/marick/root.htm">Brian
Marick</A>, Eiji Nabika, <A HREF="http://www.ews.uiuc.edu/~zhan1/">John
(Zhijiang) Han</A>, Kevin Scheufele, Tim Ryan, Girish Maiya, Weerasak
Wittawaskul, Alejandra Garrido, Peter Hatch, and <A
HREF="http://chip.cs.uiuc.edu/~droberts">Don Roberts</A>, who
commented on several drafts of this work over the last three years.
</p>
<p>We’d like to also thank our tireless shepherd, Bobby Woolf,
who trudged through the muck of several earlier versions of this
paper.</p>
<p>
Naturally, we’d like to acknowledge the members of our PLoP
’97 Conference Writer’s Workshop, Norm Kerth, Hans Rohnert,
Clark Evans, Shai Ben-Yehuda, Lorraine Boyd, Alejandra Garrido, <A
HREF="http://www.ncsa.uiuc.edu/people/daman/">Dragos Manolescu</A>,
Gerard Meszaros, Kyle Brown, <A
HREF="http://st-www.cs.uiuc.edu/users/johnson/">Ralph Johnson</A>,
and Klaus Renzel.
</p>
<p>Lorrie Boyd provided some particularly poignant observations on
scale, and the human cost of projects that fail.</p>
<p>UIUC Architecture professor Bill Rose provided some keen
insights on the durability of housing stock, and history of the
estrangement of architects from builders.</p>
<p>
Thanks to <A HREF="http://www.enteract.com/~bradapp/">Brad
Appleton</A>, <A HREF="http://www.fti-consulting.com/users/beedlem/">Michael
Beedle</A>, Russ Hurlbut, and the rest of the people in the <A
HREF="http://c2.com/cgi/wiki?ChicagoPatternsGroup">Chicago
Patterns Group</A> for their time, suggestions, and ruminations on reuse
and reincarnation.
<p>
Thanks to <A HREF="http://world.std.com/~berczuk/ ">Steve Berczuk</A>
and the members of the <A
HREF="http://c2.com/cgi/wiki?BostonAreaPatternsGroup">Boston Area
Patterns Group</A> for their review.
</p>
<p>
Thanks too to <A HREF="http://www.industriallogic.com/">Joshua
Kerievsky</A> and the <A
HREF="http://www.industriallogic.com/patterns/index.html">Design
Patterns Study Group of New York City</A> for their comments.
</p>
<p>
We'd like to express our gratitude as well to Paolo Cantoni, Chris
Olufson, Sid Wright, John Liu, Martin Cohen, John Potter, Richard
Helm, and <A HREF="http://www.mri.mq.edu.au/~kjx/">James Noble</A> of
the <A HREF="http://www.mri.mq.edu.au/~kjx/patterns/">Sydney
Patterns Group</A>, who workshopped this paper during the late winter,
er, summer of early 1998.
</p>
<p>
John Vlissides, Neil Harrison, Hans Rohnert, James Coplien, and <A
HREF="http://st-www.cs.uiuc.edu/users/johnson/">Ralph Johnson</A>
provided some particularly candid, incisive and useful criticism of
some of the later drafts of the paper.
</p>
<p>
A number of readers have observed, over the years, that <A
HREF="mud.html#BigBallOfMud">BIG BALL OF MUD</A> has a certain <A
HREF="http://www.m-w.com/cgi-bin/dictionary?dystopian">dystopian</A>,
Dilbert-esque quality to it. We are grateful to <A
HREF="http://www.dilbert.com/">United Features Syndicate, Inc.</A>
for not having, as of yet, asked us to remove the following cartoon
from the web-based version of <A HREF="mud.html#BigBallOfMud">BIG
BALL OF MUD</A>.
</p>
<P ALIGN="CENTER">
<A HREF="http://www.zippah.com/~dtweed/dilbert/w0726866.htm"> <IMG
SRC="../images/pictures/elbonia-900406.gif" BORDER="0"
ALT="Dilbert -- 6 April 1990">
</A>
</p>
<!-- Pattern Header -->
<A NAME="References"></A>
<table border="0" width="100%" cellspacing="0" cellpadding="2">
<tr>
<td width="100%" bgcolor="#808080" style="border: 0px">
<p align="center">
<font color="#FFFFFF" size="5"> <b>References</b>
</font>
</td>
</tr>
</table>
<!-- End of Pattern Header -->
<pre>
<b>[Alexander 1964]</b>
Christopher Alexander
<i><b>Notes on the Synthesis of Form</b></i>
Harvard University Press, Cambridge, MA, 1964
<b>[Alexander 1979]</b>
Christopher Alexander
<i><b>The Timeless Way of Building</b></i>
<a href="http://www.oup-usa.org/">Oxford University Press</A>, Oxford, UK, 1979
<b>[Alexander et. al 1977]</b>
C. Alexander, S. Ishikawa, and M. Silverstein
<a
href="http://www.amazon.com/exec/obidos/ISBN=0195019199/3970-4035166-128299"><i><b>A Pattern Language</b></i></a>
<a href="http://www.oup-usa.org/">Oxford University Press</A>, Oxford, UK, 1977
<b>[Alexander 1988]</b>
Christopher Alexander
<i><b>The Oregon Experiment</b></i>
<a href="http://www.oup-usa.org/">Oxford University Press</A>, Oxford, UK, 1988
<b>[Bach 1997]</b>
James Bach, Softwae Testing Labs
<a href="/pub/sag/Good-Enough-Software.pdf"><i><b>Good Enough Software: Beyond the Buzzword</b></i></a>
IEEE Computer, August 1997
<b>[Beck 1997]</b>
Kent Beck
<i><b><a href="http://www.prenhall.com/ptrbooks/ptr_013476904x.html">Smalltalk Best Practice Patterns</a></b></i>
<a href="http://www.prenhall.com/">Prentice Hall</A>, Upper Saddle River, NJ, 1997
<b>[Beck & Cunningham 1989]</b>
Kent Beck and <A HREF="http://www.c2.com/doc/index.html">Ward Cunningham</A>
<i><b><A HREF="http://c2.com/doc/oopsla89/paper.html">A Laboratory for Teaching Object-Oriented Thinking</a></b></i>
OOPSLA '89 Proceedings
New Orleans, LA
October 1-6 1989, pages 1-6
<b>[Beck 2000]</b>
Kent Beck
<i><b>Embracing Change: Extreme Programming Explained</b></i>
Cambridge University Press, 2000
<b>[Booch 1994]</b>
Grady Booch
<i><b>Object-Oriented Analysis and Design with Applications</b></i>
Benjamin/Cummings, Redwood City, CA, 1994
<b>[Brand 1994]</b>
<A href="http://www.well.com/user/sbb/index.html">Stewart Brand</a>
<a
href="http://www.amazon.com/exec/obidos/ISBN=0140139966/5118-8584664-924816"><b><i>How Buildings Learn: What Happens After They're Built</i></b></a>
Viking Press, 1994
<b>[Brooks 1995]</b>
<A HREF="http://www.cs.unc.edu/~brooks/">Frederick P. Brooks, Jr.</A>
<i><b>The Mythical Man-Month</b></i> (<A
HREF="http://www.yourdon.com/books/coolbooks/notes/brooks.html">Anniversary Edition</A>)
Addison-Wesley, Boston, MA, 1995
<b>[Brown et al. 1998]</b>
William J. Brown, Raphael C. Malveau,
Hays W. "Skip" McCormick III, and Thomas J. Mobray
<a href="http://www.antipatterns.com"><b><i>Antipatterns: Refactoring, Software Architectures, and Projects in Crisis</i></b></a>
Wiley Computer Publishing, John Wiley & Sons, Inc., 1998
<b>[Buschmann et al. 1996]</b>
Frank Buschmann, Regine Meunier, Hans Rohnert, Peter Sommerlad, and Michael Stahl
<b><i>Pattern-Oriented Software Architecture: A System of Patterns</i></b>
John Wiley and Sons, 1996
<b>[Coplien 1995]</b>
<A HREF="http://www.bell-labs.com/people/cope/">James O. Coplien</A>
<i><b><A
HREF="http://www.bell-labs.com/user/cope/Patterns/Process/index.html">A Generative Development-Process Pattern Language</A></b></i>
First Conference on Pattern Languages of Programs (PLoP '94)
Monticello, Illinois, August 1994
<A HREF="http://www.bell-labs.com/topic/books/PLoPD1/">Pattern Languages of Program Design</A>
edited by James O. Coplien and Douglas C. Schmidt
<a href="http://cseng.aw.com/bookdetail.qry?ISBN=0-201-60734-4&ptype=0">Addison-Wesley</A>, 1995
<b>[Cunningham 1999a]</b>
<A HREF="http://c2.com">Ward Cunningham</A>
<A HREF="http://www.c2.com/cgi/wiki?PeterPrincipleProgramming"><B><I>Peter Principle of Programming</I></B></A>
Portland Pattern Repository
13 August 1999
<A HREF="http://www.c2.com/cgi/wiki?PeterPrincipleProgramming">http://www.c2.com/cgi/wiki?PeterPrincipleProgramming</A>
<b>[Cunningham 1999b]</b>
<A HREF="http://c2.com">Ward Cunningham</A>
<A HREF="http://www.c2.com/cgi/wiki?TheMostComplexWhichCanBeMadeToWork"><I><B>The Most Complicated Thing that Could Possible Work</B></I></A>
Portland Pattern Repository
13 August 1999
<A HREF="http://www.c2.com/cgi/wiki?TheMostComplexWhichCanBeMadeToWork">http://www.c2.com/cgi/wiki?TheMostComplexWhichCanBeMadeToWork</A>
<b>[Cusumano & Shelby 1995]</b>
Michael A. Cusumano and Richard W. Shelby
<i><b>Microsoft Secrets</b></i>
The Free Press, New York, NY, 1995
<a name="Foote1988"></a><b>[Foote 1988]</b>
<a href="mud.html#BrianFoote">Brian Foote</a> (Advisor: <a
href="http://st-www.cs.uiuc.edu/users/johnson/">Ralph Johnson</a>)
<b><i><a href="../dfc/discussion.html">Designing to Facilitate Change with Object-Oriented Frameworks</A></i></b>
<A HREF="../dfc/DFC.html">Masters Thesis</A>, <a
href="http://www.laputan.com/cgi-bin/calendar?1988">1988</a>
<a href="http://www.cs.uiuc.edu/">Dept. of Computer Science</a>,
<a href="http://www.uiuc.edu/">University of Illinois at Urbana-Champaign</a>
<b>[Foote & Opdyke 1995]</b>
<a href="mud.html#BrianFoote">Brian Foote</a> and William F. Opdyke
<b><i><A HREF="../lifecycle/lifecycle.html">Lifecycle and Refactoring Patterns that Support Evolution and Reuse</a></i></b>
First Conference on Patterns Languages of Programs (PLoP '94)
Monticello, Illinois, August 1994
<a
href="http://cseng.aw.com/bookdetail.qry?ISBN=0-201-60734-4&ptype=0">Pattern Languages of Program Design</a>
edited by <a href="http://www.bell-labs.com/people/cope/">James O. Coplien</a> and <a
href="http://www.cs.wustl.edu/~schmidt/">Douglas C. Schmidt</a>
<a href="http://www.awl.com/cseng/index.html">Addison-Wesley</a>, <a
href="http://www.laputan.com/cgi-bin/calendar?1995">1995</a>
This volume is part of the <a
href="http://cseng.aw.com/seriesdetail.qry?SeriesID=34">Addison-Wesley Software Patterns Series</a>.
<b>[Foote & Yoder 1996]</b>
<a href="mud.html#BrianFoote">Brian Foote</a> and <A
HREF="http://www.joeyoder.com/">Joseph W. Yoder</a>
<i><b><a href="../metamorphosis/metamorphosis.html">Evolution, Architecture, and Metamorphosis</a></b></i>
Second Conference on Patterns Languages of Programs (PLoP '95)
Monticello, Illinois, September 1995
<a
href="http://cseng.aw.com/bookdetail.qry?ISBN=0-201-89527-7&ptype=0">Pattern Languages of Program Design 2</a>
edited by <a href="http://www.software.ibm.com/qawww/despat-expert.html">John M. Vlissides</a>, <a
href="http://www.bell-labs.com/people/cope/">James O. Coplien</a>, and Norman L. Kerth
<a href="http://www.awl.com/cseng/index.html">Addison-Wesley</a>, <a
href="http://www.laputan.com/cgi-bin/calendar?1996">1996</a>
This volume is part of the <a
href="http://cseng.aw.com/seriesdetail.qry?SeriesID=34">Addison-Wesley Software Patterns Series</a>.
<a name="FooteRoberts1998"><b>[Foote & Roberts 1998]</b></a>
<a href="mud.html#BrianFoote">Brian Foote</a> and <A
HREF="http://chip.cs.uiuc.edu/~droberts/">Don Roberts</A>
<b><i><A HREF="../lingua/lingua.html">Lingua Franca</a></i></b>
<A HREF="http://st-www.cs.uiuc.edu/~berczuk/PLoP98/">Fifth Conference on Patterns Languages of Programs</A> (<A
HREF="http://jerry.cs.uiuc.edu/~plop/plop98/final_submissions/">PLoP '98</A>)
Monticello, Illinois, <a
href="http://www.laputan.com/cgi-bin/calendar?8+1998">August 1998</a>
Technical Report #WUCS-98-25 (<a
href="http://jerry.cs.uiuc.edu/~plop/plop98/final_submissions/">PLoP '98</a>/<a
href="http://www.coldewey.com/europlop98/Program/writers.htm">EuroPLoP '98</a>), <a
href="http://www.laputan.com/cgi-bin/calendar?9+1998">September 1998</a>
<a href="http://www.cs.wustl.edu/">Department of Computer Science</a>, <a
href="http://www.wustl.edu">Washington University</a>
<a name="FooteYoder1996"><b>[Foote & Yoder 1996]</b></a>
<a href="mud.html#BrianFoote">Brian Foote</a> and <A
HREF="http://www.joeyoder.com/">Joseph W. Yoder</a>
<i><b><a href="../metamorphosis/metamorphosis.html">Evolution, Architecture, and Metamorphosis</A></b></i>
Second Conference on Patterns Languages of Programs (PLoP '95)
Monticello, Illinois, September 1995
<a
href="http://cseng.aw.com/bookdetail.qry?ISBN=0-201-89527-7&ptype=0">Pattern Languages of Program Design 2</a>
edited by <a href="http://www.software.ibm.com/qawww/despat-expert.html">John M. Vlissides</a>, <a
href="http://www.bell-labs.com/people/cope/">James O. Coplien</a>, and Norman L. Kerth
<a href="http://heg-school.aw.com/cseng/index.html">Addison-Wesley</a>, <a
href="http://www.laputan.com/cgi-bin/calendar?1996">1996</a>
This volume is part of the <a
href="http://cseng.aw.com/seriesdetail.qry?SeriesID=34">Addison-Wesley Software Patterns Series</a>.
<b>[Foote & Yoder 1998a]</b>
<a href="mud.html#BrianFoote">Brian Foote</a> and <A
HREF="http://www.joeyoder.com/">Joseph W. Yoder</a>
<i><b><a href="../selfish/selfish.html">The Selfish Class</a></b></i>
Third Conference on Patterns Languages of Programs (<a
href="http://www.cs.wustl.edu/~schmidt/jointPLoP-96.html">PLoP '96</a>)
Monticello, Illinois, <a
href="http://www.laputan.com/cgi-bin/calendar?9+1996">September 1996</a>
<a href="http://www.cs.wustl.edu/~schmidt/PLoP-96/program.html">Technical Report #WUCS-97-07</a>, <a
href="http://www.laputan.com/cgi-bin/calendar?9+1996">September 1996</a>
<a href="http://www.cs.wustl.edu/">Department of Computer Science</a>, <a
href="http://www.wustl.edu">Washington University</a>
<a
href="http://cseng.aw.com/bookdetail.qry?ISBN=0-201-31011-2&ptype=0">Pattern Languages of Program Design 3</a>
edited by <a href="http://www.oma.com./Brochure/Resumes/rmartin.html">Robert Martin</a>, <a
href="http://www.riehle.org/">Dirk Riehle</a>, and Frank Buschmann
<a href="http://www.awl.com/cseng/index.html">Addison-Wesley</a>, <a
href="http://www.laputan.com/cgi-bin/calendar?1998">1998</a>
<a href="../index.html">http://www.laputan.org</a>
<a
href="http://www.amazon.com/exec/obidos/ISBN=0201310112/7698-0074090-873253"><img
src="../images/pictures/plopd3-new.gif" alt="Order from Amazon.com"
width="103" height="140"></a>
This volume is part of the <a
href="http://cseng.aw.com/seriesdetail.qry?SeriesID=34">Addison-Wesley Software Patterns Series</a>.
Brian also wrote an <a href="../plop/vigor.html">introduction</a> for this volume.
<a name="FooteYoder1998b"><b>[Foote & Yoder 1998b]</b></a>
<a href="mud.html#BrianFoote">Brian Foote</a> and <A
HREF="http://www.joeyoder.com/">Joseph W. Yoder</a>
<b><i><A HREF="../metadata/metadata.html">Metadata</a></i></b>
<A HREF="http://st-www.cs.uiuc.edu/~berczuk/PLoP98/">Fifth Conference on Patterns Languages of Programs</A> (<A
HREF="http://jerry.cs.uiuc.edu/~plop/plop98/final_submissions/">PLoP '98</A>)
Monticello, Illinois, <a
href="http://www.laputan.com/cgi-bin/calendar?8+1998">August 1998</a>
Technical Report #WUCS-98-25 (<a
href="http://jerry.cs.uiuc.edu/~plop/plop98/final_submissions/">PLoP '98</a>/<a
href="http://www.coldewey.com/europlop98/Program/writers.htm">EuroPLoP '98</a>), <a
href="http://www.laputan.com/cgi-bin/calendar?9+1998">September 1998</a>
<a href="http://www.cs.wustl.edu/">Department of Computer Science</a>, <a
href="http://www.wustl.edu">Washington University</a>
<b>[Fowler 1999]</b>
Martin Fowler
<b><i>Refactoring: Improving the Design of Existing Code</i></b>
Addison Wesley Longman, 1999
<b>[Gabriel 1991]</b>
Richard P. Gabriel
<a href="../gabriel/worse-is-better.html"><i><b>Lisp: Good News Bad News and How to Win Big</b></i></A>
<a href="../gabriel/worse-is-better.html">http://www.laputan.org/gabriel/worse-is-better.html</a>
<b>[Gabriel 1996]</b>
Richard P. Gabriel
<i><b>Patterns of Software: Tales from the Software Community</b></I>
Oxford University Press, Oxford, UK, 1996
<a href="http://www.oup-usa.org/">http://www.oup-usa.org/</a>
<b>[Gamma et al. 1995]</b>
<A HREF="../plop/gang-of-four.html">Eric Gamma, Richard Helm, Ralph Johnson, and John Vlissides</A>
<a href="http://st-www.cs.uiuc.edu/users/patterns/DPBook/DPBook.html"><i><b>Design Patterns: Elements of Reusable Object-Oriented Software</b></I></A>
<a href="http://www.awl.com/cp/Gamma.html">Addison-Wesley Longman</a>, Reading, MA, 1995
<b>[Garlan & Shaw 1993]</b>
<a
href="http://almond.srv.cs.cmu.edu/afs/cs.cmu.edu/user/garlan/www/home.html">David Garlan</A> and <A
HREF="http://spoke.compose.cs.cmu.edu/shaweb/">Mary Shaw</A>
<i><b>An Introduction to Software Architecture</b></i>
V. Ambriola and G. Totora, editors
<I>Advances in Software Engineering and Knowledge Engineering, Vol 2.</I>
Singapore: World Scientific Publishing, 1993, pp. 1-39
<b>[Ingalls 1983]</b>
Daniel H. H. Ingalls
<b><i>The Evolution of the Smalltalk Virtual Machine</i></b>
Smalltalk-80: Bits of History, Words of Advice
edited by Glenn Krasner
Addison-Wesley, 1983
<a name="JohnsonFoote1988"><b>[Johnson & Foote 1988]</b></a>
<a href="http://st-www.cs.uiuc.edu/users/johnson/">Ralph Johnson</a> and <a
href="mud.html#BrianFoote">Brian Foote</a>
<b><i><a href="../drc/drc.html">Designing Reusable Classes</a></i></b>
Journal of Object-Oriented Programming
Volume 1, Number 2, June/July <a
href="http://www.laputan.com/cgi-bin/calendar?1988">1988</a>
<b>[Marick 1995]</b>
<a href="http://www.testing.com">Brian Marick</a>
<b><i>The Craft of Software Testing</i></b>
Prentice-Hall, Upper Saddle River, NJ, 1995
<b>[Meszaros 1997]</b>
Gerard Meszaros
<b><i>Archi-Patterns: A Process Pattern Language for Defining Architectures</i></b>
Fourth Conference on Pattern Languages of Programs (PLoP '97)
Monticello, Illinois, September 1997
<b>[Roberts & Johnson 1998]</b>
<A HREF="http://st-www.cs.uiuc.edu/~droberts">Don Roberts</A> and <a
href="http://st-www.cs.uiuc.edu/users/johnson/">Ralph E. Johnson</a>
<A HREF="http://st-www.cs.uiuc.edu/~droberts/evolve.html"><b><i>Evolve Frameworks into Domain-Specific Languages</i></b></A>
Third Conference on Patterns Languages of Programs (<a
href="http://www.cs.wustl.edu/~schmidt/jointPLoP-96.html">PLoP '96</a>)
Monticello, Illinois, <a
href="http://www.laputan.com/cgi-bin/calendar?9+1996">September 1996</a>
<a href="http://www.cs.wustl.edu/~schmidt/PLoP-96/program.html">Technical Report #WUCS-97-07</a>, <a
href="http://www.laputan.com/cgi-bin/calendar?9+1996">September 1996</a>
<a href="http://www.cs.wustl.edu/">Department of Computer Science</a>, <a
href="http://www.wustl.edu">Washington University</a>
<a
href="http://cseng.aw.com/bookdetail.qry?ISBN=0-201-31011-2&ptype=0">Pattern Languages of Program Design 3</a>
edited by <a href="http://www.oma.com./Brochure/Resumes/rmartin.html">Robert Martin</a>, <a
href="http://www.riehle.org/">Dirk Riehle</a>, and Frank Buschmann
<a href="http://www.awl.com/cseng/index.html">Addison-Wesley</a>, <a
href="http://www.laputan.com/cgi-bin/calendar?1998">1998</a>
<b>[Shaw 1996]</b>
<A HREF="http://spoke.compose.cs.cmu.edu/shaweb/">Mary Shaw</A>
<b><i>Some Patterns for Software Architectures</i></b>
Second Conference on Patterns Languages of Programs (PLoP '95)
Monticello, Illinois, September 1995
<a
href="http://cseng.aw.com/bookdetail.qry?ISBN=0-201-89527-7&ptype=0">Pattern Languages of Program Design 2</a>
edited by <a href="http://www.software.ibm.com/qawww/despat-expert.html">John M. Vlissides</a>, <a
href="http://www.bell-labs.com/people/cope/">James O. Coplien</a>, and Norman L. Kerth
<a href="http://heg-school.aw.com/cseng/index.html">Addison-Wesley</a>, <a
href="http://www.laputan.com/cgi-bin/calendar?1996">1996</a>
<b>[Simon 1969]</b>
Herbert A. Simon
<b><i>The Sciences of the Artificial</i></b>
MIT Press, Cambridge, MA, 1969
<b>[Swift 1726]</b>
Johnathan Swift
<i><b><A HREF="http://www.jaffebros.com/lee/gulliver/">Travels Into Several Remote Nations Of The World. <BR>In four parts. By Lemuel Gulliver, First a Surgeon, and then a Captain of several Ships.</a></b></i>
B. Motte, London, 1726.
<b>[Vitruvius 20 B.C.]</b>
Marcus Vitruvius Pollio (60 B.C-20 B.C.)
<b><I><A
HREF="http://www.ukans.edu/history/index/europe/ancient_rome/E/Roman/Texts/Vitruvius/home.html">De Architectura</A></i></b>
translated by Joseph Gwilt
Priestley and Weale, London, 1826
</pre>
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**[Brian Foote](../index.html)
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Foote](../index.html)** and **[Joseph Yoder](http://www.joeyoder.com/)**
This paper was twice [featured](http://slashdot.org/articles/00/04/29/0926241.shtml)
in **[Slashdot](http://slashdot.org/)**
[![Badge](../images/icons/DailyImageBadge.gif)](http://www.dailyimage.com)
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| --- |
|
**Contents**
|
[![PLoPD4 Cover](../images/pictures/harrison-small.jpg)](http://cseng.awl.com/seriesdetail.qry?SeriesID=34)
1. [Abstract](mud.html#Abstract)- [Introduction](mud.html#Introduction)- [Forces](mud.html#Forces)- [Big Ball Of Mud](mud.html#BigBallOfMud)- [Throwaway Code](mud.html#ThrowAwayCode)- [Piecemeal Growth](mud.html#PiecemealGrowth)- [Keep It Working](mud.html#KeepItWorking)- [Shearing Layers](mud.html#ShearingLayers)- [Sweeping It
Under The Rug](mud.html#SweepingItUnderTheRug)- [Reconstruction](mud.html#Reconstruction)- [Conclusion](mud.html#Conclusion)- [Acknowledgments](mud.html#Acknowledgments)- [References](mud.html#References)
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| --- |
|
**Abstract**
|
While much attention has been focused on high-level software
architectural patterns, what is, in effect, the de-facto standard
software architecture is seldom discussed. This paper examines this
most frequently deployed of software architectures: the [BIG BALL OF MUD](mud.html#BigBallOfMud). A [BIG BALL OF MUD](mud.html#BigBallOfMud) is a casually, even
haphazardly, structured system. Its organization, if one can call it
that, is dictated more by expediency than design. Yet, its enduring
popularity cannot merely be indicative of a general disregard for
architecture.
These patterns explore the forces that encourage the emergence of a [BIG BALL OF MUD](mud.html#BigBallOfMud), and the undeniable
effectiveness of this approach to software architecture. What are the
people who build them doing right? If more high-minded architectural
approaches are to compete, we must understand what the forces that
lead to a [BIG BALL OF MUD](mud.html#BigBallOfMud) are, and
examine alternative ways to resolve them.
A number of additional patterns emerge out of the [BIG BALL OF MUD](mud.html#BigBallOfMud). We discuss them in
turn. Two principal questions underlie these patterns: Why are so many
existing systems architecturally undistinguished, and what can we do
to improve them?
| |
| --- |
|
**Introduction**
|
Over the last several years, a number of authors [Garlan & Shaw
1993] [Shaw 1996] [Buschmann et. al. 1996] [Meszaros 1997] have
presented patterns that characterize high-level software
architectures, such as PIPELINE and LAYERED ARCHITECTURE. In an ideal
world, every system would be an exemplar of one or more such
high-level patterns. Yet, this is not so. The architecture that
actually predominates in practice has yet to be discussed: the [BIG BALL OF MUD](mud.html#BigBallOfMud).
[![Lennon Serves Too Much Spaghetti](../images/pictures/spaghetti-medium.jpg)](http://oak.cats.ohiou.edu/~ba116594/mmt.html)
A [BIG BALL OF MUD](mud.html#BigBallOfMud) is haphazardly
structured, sprawling, sloppy, duct-tape and bailing wire, [spaghetti](http://www.mdagroup.com/computing/spaghett.htm) [code](http://www.cs.brandeis.edu/~dkw/C-humor/pasta.txt) [jungle](http://leb.net/~tonyk/jargon/entry.cgi?idx=1710).
We’ve all seen them. These systems show unmistakable signs of
unregulated growth, and repeated, [expedient](http://home.swbell.net/mck9/cobol/style/rewrite.html)
repair. Information is shared promiscuously among distant elements of
the system, often to the point where nearly all the important
information becomes global or duplicated. The overall structure of the
system may never have been well defined. If it was, it may have [eroded](http://garynorth.com/y2k/detail_.cfm/881) beyond
recognition. Programmers with a shred of architectural sensibility
shun these quagmires. Only those who are unconcerned about
architecture, and, perhaps, are comfortable with the inertia of the
day-to-day chore of patching the holes in these failing dikes, are
content to work on such systems.
Still, this approach endures and thrives. Why is this
architecture so popular? Is it as bad as it seems, or might it serve
as a way-station on the road to more enduring, elegant artifacts? What
forces drive good programmers to build ugly systems? Can we avoid
this? Should we? How can we make such systems better?
We present the following seven patterns:
![](../images/icons/blueball.gif)
![](../images/icons/blueball.gif)
![](../images/icons/blueball.gif)
![](../images/icons/blueball.gif) [KEEP IT WORKING](mud.html#KeepItWorking)
![](../images/icons/blueball.gif) [SHEARING LAYERS](mud.html#ShearingLayers)
![](../images/icons/blueball.gif) [SWEEPING IT UNDER THE RUG](mud.html#SweepingItUnderTheRug)
![](../images/icons/blueball.gif) [RECONSTRUCTION](mud.html#Reconstruction)
Why does a system become a [BIG
BALL OF MUD](mud.html#BigBallOfMud)? Sometimes, big, ugly systems emerge from [THROWAWAY
CODE](mud.html#ThrowAwayCode). [THROWAWAY CODE](mud.html#ThrowAwayCode) is
quick-and-dirty code that was intended to be used only once and then
discarded. However, such code often takes on a life of its own,
despite casual structure and poor or non-existent documentation. It
works, so why fix it? When a related problem arises, the quickest way
to address it might be to expediently modify this working code, rather
than design a proper, general program from the ground up. Over time, a
simple throwaway program begets a [BIG
BALL OF MUD](mud.html#BigBallOfMud).
Even systems with well-defined architectures are prone to structural
erosion. The relentless onslaught of changing requirements that any
successful system attracts can gradually undermine its structure.
Systems that were once tidy become overgrown as [PIECEMEAL GROWTH](mud.html#PiecemealGrowth) gradually allows
elements of the system to sprawl in an uncontrolled fashion.
If such sprawl continues unabated, the structure of the system can
become so badly compromised that it must be abandoned. As with a
decaying neighborhood, a downward spiral ensues. Since the system
becomes harder and harder to understand, maintenance becomes more
expensive, and more difficult. Good programmers refuse to work there.
Investors withdraw their capital. And yet, as with neighborhoods,
there are ways to avoid, and even reverse, this sort of decline. As
with anything else in the universe, counteracting entropic forces
requires an investment of energy. Software [gentrification](http://www.m-w.com/cgi-bin/dictionary?gentrification)
is no exception. The way to arrest entropy in software is to refactor
it. A sustained commitment to refactoring can keep a system from
subsiding into a BIG BALL OF MUD.
A major flood, fire, or war may require that a city be evacuated and
rebuilt from the ground up. More often, change takes place a building
or block at a time, while the city as a whole continues to function.
Once established, a strategy of [KEEPING
IT WORKING](mud.html#KeepItWorking) preserves a municipality’s vitality as it grows.
Systems and their constituent elements evolve at different rates. As
they do, things that change quickly tend to become distinct from
things that change more slowly. The [SHEARING
LAYERS](mud.html#ShearingLayers) that develop between them are like fault lines or facets that
help foster the emergence of enduring abstractions.
A simple way to begin to control decline is to cordon off the blighted
areas, and put an attractive façade around them. We call this strategy
[SWEEPING IT UNDER THE RUG](mud.html#SweepingItUnderTheRug).
In more advanced cases, there may be no alternative but to tear
everything down and start over. When total [RECONSTRUCTION](mud.html#Reconstruction) becomes necessary,
all that is left to salvage is the patterns that underlie the
experience.
Some of these patterns might appear at first to be antipatterns
[Brown et al. 1998] or straw men, but they are not, at least in the
customary sense. Instead, they seek to examine the gap between what we
preach and what we practice.
Still, some of them may strike some readers as having a schizoid
quality about them. So, for the record, let us put our cards on the
table. We are in favor of good architecture.
Our ultimate agenda is to help drain these swamps. Where
possible, architectural decline should be prevented, arrested, or
reversed. We discuss ways of doing this. In severe cases,
architectural abominations may even need to be demolished.
At the same time, we seek not to cast blame upon those who must
wallow in these mires. In part, our attitude is to "hate the sin, but
love the sinner". But, it goes beyond this. Not every backyard storage
shack needs marble columns. There are significant forces that can
conspire to compel architecture to take a back seat to functionality,
particularly early in the evolution of a software artifact.
Opportunities and insights that can allow for architectural progress
often are present later rather than earlier in the lifecycle.
A certain amount of controlled chaos is natural during
construction, and can be tolerated, as long as you clean up after
yourself eventually. Even beyond this though, a complex system may be
an accurate reflection of our immature understanding of a complex
problem. The class of systems that we can build at all may be larger
than the class of systems we can build elegantly, at least at first. A
somewhat ramshackle rat's nest might be a state-of-the-art
architecture for a poorly understood domain. This should not be the
end of the story, though. As we gain more experience in such domains,
we should increasingly direct our energies to gleaning more enduring
architectural abstractions from them.
The patterns described herein are not intended to stand alone. They
are instead set in a context that includes a number of other patterns
that we and others have described. In particular, they are set in
contrast to the lifecycle patterns, [PROTOTYPE](http://www.bell-labs.com/user/cope/Patterns/Process/section38.html)
[PHASE](../lifecycle/lifecycle.html#Prototype), [EXPANSIONARY PHASE](../lifecycle/lifecycle.html#Expand), and
[CONSOLIDATION
PHASE](../lifecycle/lifecycle.html#Consolidate), presented in [[Foote
& Opdyke 1995](../lifecycle/lifecycle.html)] and [Coplien 1995], the [SOFTWARE
TECTONICS](../metamorphosis/metamorphosis.html#SoftwareTectonics) pattern in [[Foote
& Yoder 1996](../metamorphosis/metamorphosis.html#SoftwareTectonics)], and the framework development patterns in [[Roberts
& Johnson 1998](http://st-www.cs.uiuc.edu/~droberts/evolve.html)].
Indeed, to a substantial extent, much of this chapter describes
the disease, while the patterns above describe what we believe can be
the cure: a flexible, adaptive, feedback-driven development process in
which design and refactoring pervade the lifecycle of each artifact,
component, and framework, within and beyond the applications that
incubate them.
| |
| --- |
|
**Forces**
|
A number of forces can conspire to drive even the most architecturally
conscientious organizations to produce [BIG
BALLS OF MUD](mud.html#BigBallOfMud). These pervasive, *"global" forces* are
at work in all the patterns presented. Among these forces:
*Time:* There may not be enough time to consider the [long-term](http://www.longnow.org/) architectural
implications of one’s design and implementation decisions. Even
when systems have been well designed, architectural concerns often
must yield to more pragmatic ones as a deadline starts to loom.
One reason that software architectures are so often mediocre is that
architecture frequently takes a back seat to more mundane concerns
such as cost, time-to-market, and programmer skill. Architecture is
often seen as a luxury or a frill, or the indulgent pursuit of
lily-gilding compulsives who have no concern for the bottom line.
Architecture is often treated with neglect, and even disdain. While
such attitudes are unfortunate, they are not hard to understand.
Architecture is a long-term concern. The concerns above have to be
addressed if a product is not to be stillborn in the marketplace,
while the benefits of good architecture are realized later in the
lifecycle, as frameworks mature, and reusable black-box components
emerge [[Foote & Opdyke
1995](../lifecycle/lifecycle.html)].
Architecture can be looked upon as a *Risk*, that will consume
resources better directed at meeting a fleeting market window, or as
an *Opportunity* to lay the groundwork for a commanding advantage
down the road.
Indeed, an immature architecture can be an advantage in a
growing system because data and functionality can migrate to their
natural places in the system unencumbered by artificial architectural
constraints. Premature architecture can be more dangerous than none at
all, as unproved architectural hypotheses turn into straightjackets
that discourage evolution and experimentation.
*Cost:* Architecture is expensive, especially when a new domain
is being explored. Getting the system right seems like a pointless
luxury once the system is limping well enough to ship. An investment
in architecture usually does not pay off immediately. Indeed, if
architectural concerns delay a product’s market entry for too
long, then long-term concerns may be moot. Who benefits from an
investment in architecture, and when is a return on this investment
seen? Money spent on a quick-and-dirty project that allows an
immediate entry into the market may be better spent than money spent
on elaborate, speculative architectural fishing expedition. It’s
hard to recover the value of your architectural assets if you’ve
long since gone bankrupt.
Programmers with the ability to discern and design quality
architectures are reputed to command a premium. These expenses must be
weighed against those of allowing an expensive system to slip into
premature decline and obsolescence. If you think good architecture is
expensive, try bad architecture.
*Experience:* Even when one has the time and inclination to take
architectural concerns into account, one’s experience, or lack
thereof, with the domain can limit the degree of architectural
sophistication that can be brought to a system, particularly early in
its evolution. Some programmers flourish in environments where they
can discover and develop new abstractions, while others are more
comfortable in more constrained environments (for instance, Smalltalk
vs. [Visual
Basic](http://www.hamline.edu/~wnk/cpb/199707/0884.html) programmers.) Often, initial versions of a system are vehicles
whereby programmers learn what pieces must be brought into play to
solve a particular problem. Only after these are identified do the
architectural boundaries among parts of the system start to emerge.
Inexperience can take a number of guises. There is absolute,
fresh out of school inexperience. A good architect may lack domain
experience, or a domain expert who knows the code cold may not have
architectural experience.
Employee turnover can wreak havoc on an organization’s
institutional memory, with the perhaps dubious consolation of bringing
fresh blood aboard.
*Skill:* Programmers differ in their levels of skill, as well as
in expertise, predisposition and temperament. Some programmers have a
passion for finding good abstractions, while some are skilled at
navigating the swamps of complex code left to them by others.
Programmers differ tremendously in their degrees of experience with
particular domains, and their capacities for adapting to new ones.
Programmers differ in their language and tool preferences and
experience as well.
*Visibility:* Buildings are tangible, physical structures. You
can look at a building. You can watch it being built. You can walk
inside it, and admire and critique its design.
A program’s user interface presents the public face of a
program, much as a building’s exterior manifests its
architecture. However, unlike buildings, only the people who build a
program see how it looks inside.
Programs are made of bits. The manner in which we present these
bits greatly affects our sense of how they are put together. Some
designers prefer to see systems depicted using modeling languages or
PowerPoint pictures. Others prefer prose descriptions. Still others
prefer to see code. The fashion in which we present our architectures
affects our perceptions of whether they are good or bad, clear or
muddled, and elegant or muddy.
Indeed, one of the reasons that architecture is neglected is
that much of it is "under the hood", where nobody can see
it. If the system works, and it can be shipped, who cares what it
looks like on the inside?
*Complexity:* One reason for a muddled architecture is that
software often reflects the inherent complexity of the application
domain. This is what [Brooks](http://groucho.admin.unc.edu/endeavors/end496/brooks.htm)
called "essential complexity" [Brooks 1995]. In other words,
the software is ugly because the problem is ugly, or at least not well
understood. Frequently, the organization of the system reflects the
sprawl and history of the organization that built it (as per [CONWAY’S
LAW](http://www.bell-labs.com/user/cope/Patterns/Process/section15.html) [Coplien 1995]) and the compromises that were made along the way.
Renegotiating these relationships is often difficult once the basic
boundaries among system elements are drawn. These relationships can
take on the immutable character of "site" boundaries that [Brand](http://www.well.com/user/sbb/index.html) [Brand
1994] observed in real cities. Big problems can arises when the needs
of the applications force unrestrained communication across these
boundaries. The system becomes a tangled mess, and what little
structure is there can erode further.
*Change:* Architecture is a hypothesis about the future that
holds that subsequent change will be confined to that part of the
design space encompassed by that architecture. Of course, the world
has a way of mocking our attempts to make such predictions by tossing
us the totally unexpected. A problem we might have been told was
definitely ruled out of consideration for all time may turn out to be
dear to the heart of a new client we never thought we’d have.
Such changes may cut directly across the grain of fundamental
architectural decisions made in the light of the certainty that these
new contingencies could never arise. The "right" thing to do
might be to redesign the system. The more likely result is that the
architecture of the system will be expediently perturbed to address
the new requirements, with only passing regard for the effect of these
radical changes on the structure of the system.
*Scale:* Managing a large project is a qualitatively different
problem from managing a small one, just as leading a division of
infantry into battle is different from commanding a small special
forces team. Obviously, "divide and conquer" is, in general, an
insufficient answer to the problems posed by scale. Alan Kay, during
an invited talk at OOPSLA '86 observed that "good ideas don't always
scale." That observation prompted [Henry
Lieberman](http://lcs.www.media.mit.edu/people/lieber/) to inquire "so what do we do, just scale the bad ones?"
| |
| --- |
|
**BIG BALL OF MUD** |
| |
| --- |
| *alias* |
|
SHANTYTOWN |
|
SPAGHETTI CODE |
[![Shantytown](../images/pictures/squat.jpg)](http://boone.calstatela.edu/spring476/prasarangkul.htm)
[Shantytowns](http://www.interlog.com/~rodneyb/paraguay/shantypix.html)
are squalid, sprawling slums. Everyone seems to agree they are a bad
idea, but forces conspire to promote their emergence anyway. What is
it that they are doing right?
Shantytowns are usually built from common, inexpensive materials
and simple tools. Shantytowns can be built using relatively unskilled
labor. Even though the labor force is "unskilled" in the
customary sense, the construction and maintenance of this sort of
housing can be quite labor intensive. There is little specialization.
Each housing unit is constructed and maintained primarily by its
inhabitants, and each inhabitant must be a jack of all the necessary
trades. There is little concern for infrastructure, since
infrastructure requires coordination and capital, and specialized
resources, equipment, and skills. There is little overall planning or
regulation of growth. Shantytowns emerge where there is a need for
housing, a surplus of unskilled labor, and a dearth of capital
investment. Shantytowns fulfill an immediate, local need for housing
by bringing available resources to bear on the problem. Loftier
architectural goals are a luxury that has to wait.
Maintaining a shantytown is labor-intensive and requires a broad
range of skills. One must be able to improvise repairs with the
materials on-hand, and master tasks from roof repair to ad hoc
sanitation. However, there is little of the sort of skilled
specialization that one sees in a mature economy.
All too many of our software systems are, architecturally,
little more than shantytowns. Investment in tools and infrastructure
is too often inadequate. Tools are usually primitive, and
infrastructure such as libraries and frameworks, is undercapitalized.
Individual portions of the system grow unchecked, and the lack of
infrastructure and architecture allows problems in one part of the
system to erode and pollute adjacent portions. Deadlines loom like
monsoons, and architectural elegance seems unattainable.
v v
v
As a system nears completion, its actual users may begin to work
with it for the first time. This experience may inspire changes to
data formats and the user interface that undermine architectural
decisions that had been thought to be settled. Also, as Brooks [Brooks
1995] has noted, because software is so flexible, it is often asked to
bear the burden of architectural compromises late in the development
cycle of hardware/software deliverables precisely because of its
flexibility.
This phenomenon is not unique to software. [Stewart Brand](http://www.well.com/user/sbb/index.html)
[Brand 1994] has observed that the period just prior to a
building’s initial occupancy can be a stressful period for both
architects and their clients. The money is running out, and the
finishing touches are being put on just those parts of the space that
will interact the most with its occupants. During this period, it can
become evident that certain wish-list items are not going to make it,
and that exotic experiments are not going to work. Compromise becomes
the "order of the day".
The time and money to chase perfection are seldom available, nor
should they be. To survive, we must do what it takes to get our
software working and out the door on time. Indeed, if a team completes
a project with time to spare, today’s managers are likely to take
that as a sign to provide less time and money or fewer people the next
time around.
| |
| --- |
| **You need to deliver quality
software on time, and under budget.** |
*Cost*: Architecture is a long-term investment. It is easy for
the people who are paying the bills to dismiss it, unless there is
some tangible immediate benefit, such a tax write-off, or unless
surplus money and time happens to be available. Such is seldom the
case. More often, the customer needs something working by tomorrow.
Often, the people who control and manage the development process
simply do not regard architecture as a pressing concern. If
programmers know that workmanship is invisible, and managers don't
want to pay for it anyway, a vicious circle is born.
*Skill*: Ralph Johnson is fond of observing that is inevitable
that "on average, average organizations will have average people". One
reason for the popularity and success of [BIG BALL OF MUD](mud.html#BigBallOfMud) approaches might be
that this appoach doesn't require a hyperproductive [virtuoso](http://www.onenet.net/~njtdb/casey.html) architect
at every keyboard.
*Organization*: With larger projects, cultural, process,
organizational and resource allocation issues can overwhelm technical
concerns such as tools, languages, and architecture.
It may seem to a programmer that whether to don hip boots and
wade into a swamp is a major quality-of-life matter, but programmer
comfort is but one concern to a manager, which can conflict with many
others. Architecture and code quality may strike management as frills
that have only an indirect impact on their bottom lines.
| |
| --- |
| ***Therefore*,
focus first on features and functionality, then focus on
architecture and performance.** |
The case made here resembles Gabriel’s "[Worse is Better](../gabriel/worse-is-better.html)"
arguments [Gabriel 1991] in a number of respects. Why does so much
software, despite the best intentions and efforts of developers, turn
into [BIG BALLS OF MUD](mud.html#BigBallOfMud)? Why do
slash-and-burn tactics drive out elegance? Does bad architecture drive
out good architecture?
What does this muddy code look like to the programmers in the
trenches who must confront it? Data structures may be haphazardly
constructed, or even next to non-existent. Everything talks to
everything else. Every shred of important state data may be global.
There are those who might construe this as a sort of blackboard
approach [Buschmann 1996], but it more closely resembles a grab bag of
undifferentiated state. Where state information is compartmentalized,
it may be passed promiscuously about though Byzantine back channels
that circumvent the system's original structure.
Variable and function names might be uninformative, or even
misleading. Functions themselves may make extensive use of global
variables, as well as long lists of poorly defined parameters. The
function themselves are lengthy and convoluted, and perform several
unrelated tasks. Code is duplicated. The flow of control is hard to
understand, and difficult to follow. The programmer’s intent is
next to impossible to discern. The code is simply unreadable, and
borders on indecipherable. The code exhibits the unmistakable signs of
patch after patch at the hands of multiple maintainers, each of whom
barely understood the consequences of what he or she was doing. Did we
mention documentation? What documentation?
[BIG BALL OF MUD](mud.html#BigBallOfMud) might be thought
of as an anti-pattern, since our intention is to show how passivity in
the face of forces that undermine architecture can lead to a quagmire.
However, its undeniable popularity leads to the inexorable conclusion
that it is a pattern in its own right. It is certainly a pervasive,
recurring solution to the problem of producing a working system in the
context of software development. It would seem to be the path of least
resistance when one confronts the sorts of forces discussed above.
Only by understanding the logic of its appeal can we channel or
counteract the forces that lead to a [BIG
BALL OF MUD](mud.html#BigBallOfMud).
One thing that isn’t the answer is rigid, totalitarian,
top-down design. Some analysts, designers, and architects have an
exaggerated sense of their ability to get things right up-front,
before moving into implementation. This approach leads to inefficient
resources utilization, analysis paralysis, and design straightjackets
and cul-de-sacs.
Kent Beck has observed that the way to build software is to:
Make it work. Make it right. Make it fast [Beck 1997]. "Make it
work" means that we should focus on functionality up-front, and
get something running. "Make it right" means that we should
concern ourselves with how to structure the system only after
we’ve figured out the pieces we need to solve the problem in the
first place. "Make it fast" means that we should be
concerned about optimizing performance only after we’ve learned
how to solve the problem, and after we’ve discerned an
architecture to elegantly encompass this functionality. Once all this
has been done, one can consider how to make it cheap.
When it comes to software architecture, form follows function.
Here we mean "follows" not in the traditional sense of dictating
function. Instead, we mean that the distinct identities of the
systems architectural elements often dont start to emerge until after
the code is working.
Domain experience is an essential ingredient in any framework
design effort. It is hard to try to follow a front-loaded, top-down
design process under the best of circumstances. Without knowing the
architectural demands of the domain, such an attempt is premature, if
not foolhardy. Often, the only way to get domain experience early in
the lifecycle is to hire someone who has worked in a domain before
from someone else.
The quality of one’s tools can influence a system’s
architecture. If a system’s architectural goals are inadequately
communicated among members of a team, they will be harder to take into
account as the system is designed and constructed.
Finally, engineers will differ in their levels of skill and commitment
to architecture. Sadly, architecture has been undervalued for so long
that many engineers regard life with a [BIG
BALL OF MUD](mud.html#BigBallOfMud) as normal. Indeed some engineers are particularly skilled
at learning to navigate these quagmires, and guiding others through
them. Over time, this symbiosis between architecture and skills can
change the character of the organization itself, as swamp guides
become more valuable than architects. As per [CONWAY’S
LAW](http://www.bell-labs.com/user/cope/Patterns/Process/section15.html) [Coplien 1995], architects depart in futility, while engineers
who have mastered the muddy details of the system they have built in
their images prevail. [[Foote
& Yoder 1998a](../selfish/selfish.html#LowSurfaceToVolumeRatio)] went so far as to observe that inscrutable code
might, in fact, have a survival advantage over good code, by virtue of
being difficult to comprehend and change. This advantage can extend to
those programmers who can find their ways around such code. In a land
devoid of landmarks, such guides may become indispensable.
The incentives that drive the evolution of such systems can, at
times, operate perversely. Just as it is easier to be verbose than
concise, it is easier to build complex systems than it is to build
simple ones. Skilled programmers may be able to create complexity more
quickly than their peers, and more quickly than they can document and
explain it. Like an army outrunning its logistics train, complexity
increases until it reaches the point where such programmers can no
longer reliably cope with it.
This is akin to a phenonmenon dubbed the [*PeterPrinciple
of Programming*](http://www.c2.com/cgi/wiki?PeterPrincipleProgramming) by authors on the Wiki-Wiki web [Cunninghan 1999a].
Complexity increases rapidly until the it reaches a level of
complexity just beyond that with which programmers can comfortably
cope. At this point, complexity and our abilities to contain it reach
an uneasy equilibrium. The blitzkrieg bogs down into a siege. We built
[the most complicated system that can possible work](http://www.c2.com/cgi/wiki?TheMostComplexWhichCanBeMadeToWork) [Cunningham
1999b].
[![](../images/pictures/mauldin-warm-mud.gif)](http://www.45thdivisionmuseum.com/Mainmuseum/Mauldin2.htm)
Such code can become a personal fiefdom, since the author care
barely understand it anymore, and no one else can come close. Once
simple repairs become all day affairs, as the code turns to mud. It
becomes increasingly difficult for management to tell how long such
repairs ought to take. Simple objectives turn into trench warfare.
Everyone becomes resigned to a turgid pace. Some even come to prefer
it, hiding in their cozy foxholes, and making their two line-per-day
repairs.
It is interesting to ask whether some of the differences in
productivity seen between hyper-productive organizations and typical
shops are due not to differences in talent, but differences in
terrain. Mud is hard to march through. The hacker in the trenches must
engage complexity in hand-to-hand combat every day. Sometimes,
complexity wins.
Status in the programmer's primate pecking order is often earned
through ritual displays of cleverness, rather than through
workman-like displays of simplicity and clarity. That which a culture
glorifies will flourish.
Yet, a case can be made that the casual, undifferentiated structure of
a [BIG BALL OF MUD](mud.html#BigBallOfMud) is one of its
secret advantages, since forces acting between two parts of the system
can be directly addressed without having to worry about undermining
the system’s grander architectural aspirations. These aspirations
are modest ones at best in the typical [BIG
BALL OF MUD](mud.html#BigBallOfMud). Indeed, a casual approach to architecture is emblematic
of the early phases of a system’s evolution, as programmers,
architects and users learn their way around the domain [[Foote & Opdyke
1995](../lifecycle/lifecycle.html#Prototype)]. During the [PROTOTYPE](../lifecycle/lifecycle.html#Prototype)
and [EXPANSIONARY
PHASES](../lifecycle/lifecycle.html#Expand) of a systems evolution, expedient, white-box inheritance-based
code borrowing, and a relaxed approach to encapsulation are common.
Later, as experience with the system accrues, the grain of the
architectural domain becomes discernable, and more durable black-box
components begin to emerge. In other words, it’s okay if the
system looks at first like a [BIG
BALL OF MUD](mud.html#BigBallOfMud), at least until you know better.
![Mud-based Architecture](../images/pictures/mud-house.gif)
v v
v
[Brian Marick](http://www.stlabs.com/marick/root.htm) first
suggested the name "[BIG BALL
OF MUD](mud.html#BigBallOfMud)" as a name for these sort of architectures, and the
observation that this was, perhaps, the dominant architecture
currently deployed, during a meeting of the [University of
Illinois Software Architecture Group](http://st-www.cs.uiuc.edu/research-gp.html) several years ago. We have been
using the term ever since. The term itself, in turn, appears to have [arisen](http://www.bath.ac.uk/~masjap/TYL/history.html)
during the '70s as a [characterization](http://www.cs.unm.edu/~hollan/cs257/description.html)
of [Lisp](http://www.cosc.canterbury.ac.nz/~wolfgang/cosc302/Chap2.3.html).
[BIG BALL OF MUD](mud.html#BigBallOfMud) architectures
often emerge from throw-away prototypes, or [THROWAWAY CODE](mud.html#ThrowAwayCode), because the
prototype is kept, or the disposable code is never disposed of. (One
might call these "[little
balls of mud](http://www.muang.com/rice/plant.html)".)
They also can emerge as gradual maintenance and [PIECEMEAL GROWTH](mud.html#PiecemealGrowth) impinges upon
the structure of a mature system. Once a system is working, a good way
to encourage its growth is to [KEEP
IT WORKING](mud.html#KeepItWorking). When the [SHEARING
LAYERS](mud.html#ShearingLayers) that emerge as change drives the system's evolution run
against the existing grain of the system, its structure can be
undermined, and the result can be a [BIG
BALL OF MUD](mud.html#BigBallOfMud).
The [PROTOTYPE
PHASE](../lifecycle/lifecycle.html#Prototype) and [EXPANSION
PHASE](../lifecycle/lifecycle.html#Expand) patterns in [[Foote
& Opdyke 1995](../lifecycle/lifecycle.html)] both emphasize that a period of exploration and
experimentation is often beneficial before making enduring
architectural commitments.
However, these activities, which can undermine a system's structure
should be interspersed with [CONSOLIDATION
PHASES](../lifecycle/lifecycle.html#Consolidate) [[Foote & Opdyke
1995](../lifecycle/lifecycle.html)], during which opportunities to refactor the system to enhance
its structure are exploited. Proponents of [Extreme Programming](http://www.xprogramming.com) [Beck
2000] also emphasize continuous coding and refactoring.
[Brand 1994] observes that buildings with large spaces punctuated with
regular columns had the paradoxical effect of encouraging the
innovative reuse of space precisely because they [*constrained*](../chaos/chaos.html) the design space.
Grandiose flights of architectural fancy weren’t possible, which
reduced the number of design alternatives that could be put on the
table. Sometimes [FREEDOM
FROM CHOICE](../dfc/discussion.html#O2isEasy) [Foote 1988] is what we really want.
One of mud's most effective enemies is sunshine. Subjecting
convoluted code to scrutiny can set the stage for its refactoring,
repair, and rehabilitation. Code reviews are one mechanism one can use
to expose code to daylight.
Another is the [Extreme
Programming](http://www.xprogramming.com) practice of pair programming [Beck 2000]. A pure pair
programming approach requires that every line of code written be added
to the system with two programmers present. One types, or "drives",
while the other "rides shotgun" and looks on. In contrast to
traditional solitary software production practices, pair programming
subjects code to immediate scrutiny, and provides a means by which
knowledge about the system is rapidly disseminated.
Indeed, reviews and pair programming provide programmers with
something their work would not otherwise have: an audience. Sunlight,
it is said is a powerful disinfectant. Pair-practices add an element
of performance to programming. An immediate audience of one's peers
provides immediate incentives to programmers to keep their code clear
and comprehensible, as well as functional.
An additional benefit of pairing is that accumulated wisdom and best
practices can be [rapidly
disseminated](../chaos/chaos.html) throughout an organization through successive pairings.
This is, incidentally, the same benefit that sexual reproduction
brought to the genome.
By contrast, if no one ever looks at code, everyone is free to
think they are better than average at producing it. Programmers will,
instead, respond to those relatively perverse incentives that do
exist. Line of code metrics, design documents, and other indirect
measurements of progress and quality can become central concerns.
There are three ways to deal with [BIG
BALLS OF MUD](mud.html#BigBallOfMud). The first is to keep the system healthy.
Conscientiously alternating periods of [EXPANSION](../lifecycle/lifecycle.html#Expand) with periods
of [CONSOLIDATION](../lifecycle/lifecycle.html#Consolidate),
refactoring and repair can maintain, and even enhance a system's
structure as it evolves. The second is to throw the system away and
start over. The [RECONSTRUCTION](mud.html#Reconstruction)
pattern explores this drastic, but frequently necessary alternative.
The third is to simply surrender to entropy, and wallow in the mire.
Since the time of Roman architect [Marcus
Vitruvius](http://www.cs.cmu.edu/afs/cs.cmu.edu/project/vit/www/index.html), [[Vitruvius
20 B.C.](http://www.ukans.edu/history/index/europe/ancient_rome/E/Roman/Texts/Vitruvius/home*.html)] architects have focused on his trinity of desirables: *Firmitas*
(**strength**), *Utilitas* (**utility**), and *Venustas*
(**beauty**). A [BIG BALL OF MUD](mud.html#BigBallOfMud)
usually represents a triumph of utility over aesthetics, because
workmanship is sacrificed for functionality. Structure and durability
can be sacrificed as well, because an incomprehensible program defies
attempts at maintenance. The frenzied, feature-driven "bloatware"
phenomenon seen in many large consumer software products can be seen
as evidence of designers having allowed purely utilitarian concerns to
dominate software design.
| |
| --- |
|
**THROWAWAY
CODE**
|
| |
| --- |
| *alias* |
| QUICK HACK |
| KLEENEX CODE |
| DISPOSABLE CODE |
| SCRIPTING |
| KILLER DEMO |
| PERMANENT PROTOTYPE |
| BOOMTOWN |
[![](../images/pictures/landfill.jpg)](http://www.users.csbsju.edu/~jwberndt/garbage.html)
v v
v
A homeowner might erect a temporary storage shed or car port,
with every intention of quickly tearing it down and replacing it with
something more permanent. Such structures have a way of enduring
indefinitely. The money expected to replace them might not become
available. Or, once the new structure is constructed, the temptation
to continue to use the old one for "a while" might be hard
to resist.
Likewise, when you are prototyping a system, you are not usually
concerned with how elegant or efficient your code is. You know that
you will only use it to prove a concept. Once the prototype is done,
the code will be thrown away and written properly. As the time nears
to demonstrate the prototype, the temptation to load it with
impressive but utterly inefficient realizations of the system’s
expected eventual functionality can be hard to resist. Sometimes, this
strategy can be a bit too successful. The client, rather than funding
the next phase of the project, may slate the prototype itself for
release.
| |
| --- |
| **You need an immediate fix
for a small problem, or a quick prototype or proof of concept.** |
*Time*, or a lack thereof, is frequently the
decisive force that drives programmers to write [THROWAWAY CODE](mud.html#ThrowAwayCode). Taking the time to
write a proper, well thought out, well documented program might take
more time that is available to solve a problem, or more time that the
problem merits. Often, the programmer will make a frantic dash to
construct a minimally functional program, while all the while
promising him or herself that a better factored, more elegant version
will follow thereafter. They may know full well that building a
reusable system will make it easier to solve similar problems in the
future, and that a more polished architecture would result in a
system that was easier to maintain and extend.
Quick-and-dirty coding is often rationalized as being a
stopgap measure. All too often, time is never found for this follow
up work. The code languishes, while the program flourishes.
| |
| --- |
| ***Therefore*, produce, by any
means available, simple, expedient, disposable code that adequately
addresses just the problem at-hand.** |
[THROWAWAY CODE](mud.html#ThrowAwayCode) is often written
as an alternative to reusing someone else’s more complex code.
When the deadline looms, the certainty that you can produce a sloppy
program that works yourself can outweigh the unknown cost of learning
and mastering someone else’s library or framework.
Programmers are usually not domain experts, especially at first. Use
cases or [CRC](http://www.c2.com/doc/crc/draw.html) [cards](http://www.du.edu/~mschwart/oo_review.html) [[Beck &
Cunningham 1989](http://c2.com/doc/oopsla89/paper.html)] can help them to discover domain objects. However,
nothing beats building a prototype to help a team learn its way around
a domain.
When you build a prototype, there is always the risk that
someone will say "that's good enough, ship it". One way to minimize
the risk of a prototype being put into production is to write the
prototype in using a language or tool that you couldn't possibly use
for a production version of your product. Proponents of
[Extreme Programming](http://www.xprogramming.com) [Beck
2000] often construct quick, disposable prototypes called "spike
solutions". Prototypes help us learn our way around the problem space,
but should never be mistaken for good designs [[Johnson & Foote 1988](../drc/drc.html)].
Not every program need be a palace. A simple throwaway program is like
a tent city or a mining boomtown, and often has no need for fifty year
solutions to its problems, given that it will give way to a ghost town
in five.
The real problem with
[THROWAWAY CODE](mud.html#ThrowAwayCode) comes when it
isn't thrown away.
v v
v
The production of [THROWAWAY CODE](mud.html#ThrowAwayCode)
is a nearly universal practice. Any software developer, at any skill
or experience level, can be expected to have had at least occasional
first-hand experience with this approach to software development. For
example, in the patterns community, two examples of quick-and-dirty
code that have endured are the [PLoP
online registration](http://jerry.cs.uiuc.edu/plop/chili98/chili-register.html) code, and the [Wiki-Wiki Web](http://c2.com/cgi/wiki?WelcomeVisitors)
pages.
The EuroPLoP/PLoP/UP online registration code was, in effect, a
distributed web-based application that ran on four different machines
on two continents. Conference information was maintained on a machine
in St. Louis, while registration records were kept on machines in
Illinois and Germany. The system could generate web-based reports of
registration activity, and now even instantaneously maintaineed an
online attendees list. It began life in 1995 as a quick-and-dirty
collection of HTML, scavenged C demonstration code, and csh scripts.
It was undertaken largely as an experiment in web-based form
processing prior to PLoP ‘95, and, like so many things on the
Web, succeeded considerably beyond the expectations of its authors.
Today, it is still essentially the same collection of HTML, scavenged
C demonstration code, and csh scripts. As such, it showcases how
quick-and-dirty code can, when successful, take on a life of its own.
The original C code and scripts probably contained fewer than
three dozen original lines of code. Many lines were cut-and-paste jobs
that differed only in the specific text they generate, or fields that
they check.
Here’s an example of one of the scripts that generates the
attendance report:
echo "<H2>Registrations: <B>" `ls | wc -l`
"</B></H2>"
echo
"<CODE>"
echo "Authors: <B>"
`grep 'Author = Yes' \* | wc -l` "</B>"
echo
"<BR>"
echo "Non-Authors:
<B>" `grep 'Author = No' \* | wc -l` "</B>"
echo "<BR><BR>"
This script is slow and inefficient, particularly as the number of
registrations increases, but not least among its virtues is the fact
that it *works*. Were the number of attendees to exceed more than
around one hundred, this script would start to perform so badly as to
be unusable. However, since hundreds of attendees would exceed the
physical capacity of the conference site, we knew the number of
registrations would have been limited long before the performance of
this script became a significant problem. So while this approach is,
in general, a lousy way to address this problem, it is perfectly
satisfactory within the confines of the particular purpose for which
the script has ever actually been used. Such practical constraints are
typical of [THROWAWAY CODE](mud.html#ThrowAwayCode), and
are more often than not undocumented. For that matter, everything
about [THROWAWAY CODE](mud.html#ThrowAwayCode) is more
often than not undocumented. When documentation exists, it is
frequently not current, and often not accurate.
The Wiki-Web [code](http://c2.com/cgi/wiki?MoreAboutMechanics)
at [www.c2.com](http://www.c2.com) also started as a CGI
experiment undertaken by Ward Cunningham also succeeded beyond the
author’s expectations. The name "wiki" is one of
Ward’s personal jokes, having been taken from a Hawaiian word for
"quick" that the author had seen on an airport van on a
vacation in Hawaii. Ward has subsequently used the name for a number
of quick-and-dirty projects. The Wiki Web is unusual in that any
visitor may change anything that anyone else has written
indiscriminately. This would seem like a recipe for vandalism, but in
practice, it has worked out well. In light of the system’s
success, the author has subsequently undertaken additional work to
polish it up, but the same quick-and-dirty Perl CGI core remains at
the heart of the system.
Both systems might be thought of as being on the verge of graduating
from little balls of mud to [BIG
BALLS OF MUD](mud.html#BigBallOfMud). The registration system’s C code *[metastasized](../dfc/discussion.html#Skeletons)* from one of
the NCSA HTTPD server demos, and still contains zombie code that
testifies to this heritage. At each step, [KEEPING IT WORKING](mud.html#KeepItWorking) is a premiere
consideration in deciding whether to extend or enhance the system.
Both systems might be good candidates for [RECONSTRUCTION](mud.html#Reconstruction), were the
resources, interest, and audience present to justify such an
undertaking. In the mean time, these systems, which are still
sufficiently well suited to the particular tasks for which they were
built, remain in service. Keeping them on the air takes far less
energy than rewriting them. They continue to evolve, in a [PIECEMEAL](mud.html#PiecemealGrowth) fashion, a little at a
time.
You can ameloriate the architectural erosion that can be caused
by quick-and-dirty code by isolating it from other parts of your
system, in its own objects, packages, or modules. To the extent that
such code can be quarantined, its ability to affect the integrity of
healthy parts of a system is reduced.
Once it becomes evident that a purportedly disposable artifact is
going to be around for a while, one can turn one's attention to
improving its structure, either through an iterative process of [PIECEMEAL GROWTH](mud.html#PiecemealGrowth), or via a fresh
draft, as discussed in the [RECONSTRUCTION](mud.html#Reconstruction)
pattern.
[![Rhyolite](../images/pictures/rhyolite-small.jpg)](http://www.truelink.net/user/cliffymel/dvalley.htm)
From *boomtown* to *ghost
town*:
The mining town of **Rhyolite**, in Death Valley,
was briefly the third largest city in Nevada.
Then the ore
ran out.
| |
| --- |
|
**PIECEMEAL GROWTH** |
| |
| --- |
| *alias* |
| URBAN SPRAWL |
| ITERATIVE-INCREMENTAL
DEVELOPMENT |
[![Mir Complex](../images/pictures/Mir-Mud.gif)](http://liftoff.msfc.nasa.gov/RealTime/JTrack/Spacecraft.html)
The Russian [Mir ("Peace") Space Station](http://www.maximov.com/Mir/)
Complex was [designed](http://www.maximov.com/Mir/mirdesign.html)
for reconfiguration and [modular
growth](http://www.spaceviews.com/features/mir/display/index.html). The Core module was launched in 1986, and the Kvant
("Quantum") and Kvant-2 modules joined the complex in 1987 and 1989.
The Kristall ("Crystal") module was added in 1990. The Spektr
("Spectrum") and shuttle Docking modules were added in 1995, the
latter surely a [development](http://shuttle-mir.nasa.gov/)
not anticipated in 1986. The station’s final module, Priroda
("Nature"), was launched in 1996. The common core and independent
maneuvering capabilities of several of the modules have allowed the
complex to be [rearranged](http://www.hq.nasa.gov/osf/mir/)
several times as it has grown.
[![Urban Sprawl in Colorado](../images/pictures/sprawl-small.jpg)](http://www.sigs.com/publications/docs/objm/9704/9704.booch.html)
Urban planning has an [uneven](http://www.architectureweek.com/2001/0822/culture_1-2.html)
history of success. For instance, Washington D.C. was laid out
according to a [master plan](http://www.nbm.org/Capital/)
designed by the French architect [L’Enfant](http://www.nps.gov/nama/lenfant.htm). The
capitals of
Brazil ([Brasilia](http://www.macalstr.edu/~geograph/world-urbanization/jmoersch/geography.html))
and Nigeria ([Abuja](http://cityguide.lycos.com/africa/westcentral_africa/NGAAbuja.html))
started as paper cities as well. Other cities, such as [Houston](http://www.patternlanguage.com/leveltwo/archivesframe.htm?/leveltwo/../archives/alexander1.htm),
have grown without any overarching plan to guide them. Each approach
has its problems. For instance, the radial street plans in
L’Enftant’s master plan become awkward past a certain
distance from the center. The lack of any plan at all, on the other
hand, leads to a patchwork of residential, commercial, and industrial
areas that is dictated by the capricious interaction of local forces
such as land ownership, capital, and zoning. Since concerns such as
recreation, shopping close to homes, and noise and pollution away from
homes are not brought directly into the mix, they are not adequately
addressed.
Most cities are more like Houston than Abuja. They may begin as
settlements, subdivisions, docks, or railway stops. Maybe people were
drawn by gold, or lumber, access to transportation, or empty land. As
time goes on, certain settlements achieve a critical mass, and a
positive feedback cycle ensues. The city’s success draws
tradesmen, merchants, doctors, and clergymen. The growing population
is able to support infrastructure, governmental institutions, and
police protection. These, in turn, draw more people. Different
sections of town develop distinct identities. With few exceptions,
(Salt Lake City comes to mind) the founders of these settlements never
stopped to think that they were founding major cities. Their ambitions
were usually more modest, and immediate.
[![Brasilia](../images/pictures/brasilia09.jpg)](http://www.geocities.com/~augusto_areal/minis_ic.htm)
v v
v
It has become fashionable over the last several years to take
pot shots at the "traditional" waterfall process model. It may seem to
the reader that attacking it is tantamount to flogging a dead horse.
However, if it be a dead horse, it is a tenacious one. While the
approach itself is seen by many as having been long since discredited,
it has spawned a legacy of rigid, top-down, front-loaded processes and
methodologies that endure, in various guises, to this day. We can do
worse that examine the forces that led to its original development.
In the days before waterfall development, programming pioneers
employed a simple, casual, relatively undisciplined "code-and-fix"
approach to software development. Given the primitive nature of the
problems of the day, this approach was frequently effective. However,
the result of this lack of discipline was, all too often, a [BIG BALL OF MUD](mud.html#BigBallOfMud).
The waterfall approach arose in response to this muddy morass.
While the code-and-fix approach might have been suitable for small
jobs, it did not scale well. As software became more complex, it would
not do to simply gather a room full of programmers together and tell
them to go forth and code. Larger projects demanded better planning
and coordination. Why, it was asked, can't software be engineered like
cars and bridges, with a careful analysis of the problem, and a
detailed up-front design prior to implementation? Indeed, an
examination of software development costs showed that problems were
many times more expensive to fix during maintenance than during
design. Surely it was best to mobilize resources and talent up-front,
so as to avoid maintenance expenses down the road. It's surely wiser
to route the plumbing correctly now, before the walls are up, than to
tear holes in them later. Measure twice, cut once.
One of the reasons that the waterfall approach was able to
flourish a generation ago was that computers and business requirements
changed at a more leisurely pace. Hardware was very expensive, often
dwarfing the salaries of the programmers hired to tend it. User
interfaces were primitive by today's standards. You could have any
user interface you wanted, as long as it was an alphanumeric "green
screen". Another reason for the popularity of the waterfall approach
was that it exhibited a comfortable similarity to practices in more
mature engineering and manufacturing disciplines.
Today's designers are confronted with a broad onslaught of
changing requirements. It arises in part from the rapid growth of
technology itself, and partially from rapid changes in the business
climate (some of which is driven by technology). Customers are used to
more sophisticated software these days, and demand more choice and
flexibility. Products that were once built from the ground up by
in-house programmers must now be integrated with third-party code and
applications. User interfaces are complex, both externally and
internally. Indeed, we often dedicate an entire tier of our system to
their care and feeding. Change threatens to outpace our ability to
cope with it.
| |
| --- |
| **Master plans are often
rigid, misguided and out of date. Users’ needs change with
time.** |
*Change:* The fundamental problem with top-down design is that
real world requirement are inevitably moving targets. You can't simply
aspire to solve the problem at hand once and for all, because, by the
time you're done, the problem will have changed out from underneath
you. You can't simply do what the customer wants, for quite often,
they don't know what they want. You can't simply plan, you have to
plan to be able to adapt. If you can't fully anticipate what is going
to happen, you must be prepared to be nimble.
*Aesthetics:* The goal of up-front design is to be able to
discern and specify the significant architectural elements of a system
before ground is broken for it. A superior design, given this mindset,
is one that elegantly and completely specifies the system's structure
before a single line of code has been written. Mismatches between
these blueprints and reality are considered aberrations, and are
treated as mistakes on the part of the designer. A better design would
have anticipated these oversights. In the presence of volatile
requirements, aspirations towards such design perfection are as vain
as the desire for a hole-in-one on every hole.
To avoid such embarrassment, the designer may attempt to cover
him or herself by specifying a more complicated, and more general
solution to certain problems, secure in the knowledge that others will
bear the burden of constructing these artifacts. When such predictions
about where complexity is needed are correct, they can indeed be a
source of power and satisfaction. This is part of their allure of
Venustas. However, sometime the anticipated contingencies never arise,
and the designer and implementers wind up having wasted effort solving
a problem that no one has ever actually had. Other times, not only is
the anticipated problem never encountered, its solution introduces
complexity in a part of the system that turns out to need to evolve in
another direction. In such cases, speculative complexity can be an
unnecessary obstacle to subsequent adaptation. It is ironic that the
impulse towards elegance can be an unintended source of complexity and
clutter instead.
In its most virulent form, the desire to anticipate and head off
change can lead to "analysis paralysis", as the thickening web of
imagined contingencies grows to the point where the design space seems
irreconcilably constrained.
| |
| --- |
| ***Therefore*, incrementally
address forces that encourage change and growth. Allow
opportunities for growth to be exploited locally, as they
occur. Refactor unrelentingly.** |
Successful software attracts a wider audience, which can, in turn,
place a broader range of requirements on it. These new requirements
can run against the grain of the original design. Nonetheless, they
can frequently be addressed, but at the cost of cutting across the
grain of existing architectural assumptions. [Foote 1988] called this
architectural erosion *[midlife generality loss](../dfc/discussion.html#Specificity)*.
When designers are faced with a choice between building something
elegant from the ground up, or undermining the architecture of the
existing system to quickly address a problem, architecture usually
loses. Indeed, this is a natural phase in a system’s evolution [[Foote & Opdyke 1995](../lifecycle/lifecycle.html)]. This
might be thought of as *messy kitchen* phase, during which pieces
of the system are scattered across the counter, awaiting an eventual
cleanup. The danger is that the clean up is never done. With real
kitchens, the board of health will eventually intervene. With
software, alas, there is seldom any corresponding agency to police
such squalor. Uncontrolled growth can ultimately be a malignant force.
The result of neglecting to contain it can be a [BIG BALL OF MUD](mud.html#BigBallOfMud).
In *How Buildings Learn*, Brand [Brand 1994] observed that what
he called *High Road* architecture often resulted in buildings
that were expensive and difficult to change, while vernacular, *Low
Road* buildings like bungalows and warehouses were, paradoxically,
much more adaptable. Brand noted that *Function melts form*, and
low road buildings are more amenable to such change. Similarly, with
software, you may be reluctant to desecrate another programmer’s
cathedral. Expedient changes to a low road system that exhibits no
discernable architectural pretensions to begin with are easier to
rationalize.
In the Oregon Experiment [Brand 1994][Alexander 1988] [Alexander](http://gee.cs.oswego.edu/dl/ca/ca/ca.html) noted:
*Large-lump development is based on the idea of **replacement**.
Piecemeal Growth is based on the idea of **repair**. …
Large-lump development is based on the fallacy that it is possible to
build perfect buildings. Piecemeal growth is based on the healthier
and more realistic view that mistakes are inevitable. … Unless
money is available for repairing these mistakes, every building, once
built, is condemned to be, to some extent unworkable. …
Piecemeal growth is based on the assumption that adaptation between
buildings and their users is necessarily a slow and continuous
business which cannot, under any circumstances, be achieve in a
single leap.*
Alexander has noted that our mortgage and capital expenditure
policies make large sums of money available up front, but do nothing
to provide resources for maintenance, improvement, and evolution
[Brand 1994][Alexander 1988]. In the software world, we deploy our
most skilled, experienced people early in the lifecycle. Later on,
maintenance is relegated to junior staff, when resources can be
scarce. The so-called maintenance phase is the part of the lifecycle
in which the price of the fiction of master planning is really paid.
It is maintenance programmers who are called upon to bear the burden
of coping with the ever widening divergence between fixed designs and
a continuously changing world. If the hypothesis that architectural
insight emerges late in the lifecycle is correct, then this practice
should be reconsidered.
Brand went on to observe *Maintenance **is** learning.* He distinguishes three levels of learning in the context of systems.
This first is habit, where a system dutifully serves its function
within the parameters for which it was designed. The second level
comes into play when the system must adapt to change. Here, it usually
must be modified, and its capacity to sustain such modification
determines it’s degree of adaptability. The third level is the
most interesting: *learning to learn*. With buildings, adding a
raised floor is an example. Having had to sustain a major upheaval,
the system adapts so that subsequent adaptations will be much less
painful.
[PIECEMEAL GROWTH](mud.html#PiecemealGrowth) can be
undertaken in an opportunistic fashion, starting with the existing,
living, breathing system, and working outward, a step at a time, in
such a way as to not undermine the system’s viability. You
enhance the program as you use it. Broad advances on all fronts are
avoided. Instead, change is broken down into small, manageable chunks.
One of the most striking things about [PIECEMEAL GROWTH](mud.html#PiecemealGrowth) is the role
played by *Feedback*. Herbert Simon [Simon 1969] has observed
that few of the adaptive systems that have been forged by evolution or
shaped by man depend on prediction as their main means of coping with
the future. He notes that two complementary mechanisms, homeostasis,
and retrospective feedback, are often far more effective. Homeostasis
insulates the system from short-range fluctuations in its environment,
while feedback mechanisms respond to long-term discrepancies between a
system's actual and desired behavior, and adjust it accordingly.
Alexander [Alexander 1964] has written extensively of the roles that
homeostasis and feedback play in adaptation as well.
If you can adapt quickly to change, predicting it becomes far less
crucial. Hindsight, as Brand observes [Brand 1994] is better than
foresight. Such rapid adaptation is the basis of one of the mantras of
[Extreme Programming](http://www.xprogramming.com) [Beck
2000]: *You're not going to need it*.
Proponents of XP (as it is called) say to pretend you are not a
smart as you think you are, and wait until this clever idea of yours
is actually required before you take the time to bring it into being.
In the cases where you were right, hey, you saw it coming, and you
know what to do. In the cases where you were wrong, you won't have
wasted any effort solving a problem you've never had when the design
heads in an unanticipated direction instead.
[Extreme Programming](http://www.xprogramming.com) relies
heavily on feedback to keep requirements in sync with code, by
emphasizing short (three week) iterations, and extensive, continuous
consultation with users regarding design and development priorities
throughout the development process. Extreme Programmers do not engage
in extensive up-front planning. Instead, they produce working code as
quickly as possible, and steer these prototypes towards what the users
are looking for based on feedback.
Feedback also plays a role in determining coding assignments.
Coders who miss a deadline are assigned a different task during the
next iteration, regardless of how close they may have been to
completing the task. This form of feedback resembles the stern justice
meted out by the jungle to the fruit of uncompetitive pairings.
[Extreme Programming](http://www.xprogramming.com) also
emphasizes testing as an integral part of the development process.
Tests are developed, ideally, before the code itself. Code is
continuously tested as it is developed.
There is a "back-to-the-future" quality to Extreme Programming. In
many respects, it resembles the blind *Code and Fix* approach.
The thing that distinguishes it is the central role played by feedback
in driving the system's evolution. This evolution is abetted, in turn,
by modern object-oriented languages and powerful refactoring tools.
Proponents of extreme programming portray it as placing minimal
emphasis on planning and up-front design. They rely instead on
feedback and continuous integration. We believe that a certain amount
of up-front planning and design is not only important, but inevitable.
No one really goes into any project blindly. The groundwork must be
laid, the infrastructure must be decided upon, tools must be selected,
and a general direction must be set. A focus on a shared architectural
vision and strategy should be established early.
Unbridled, change can undermine structure. Orderly change can
enhance it. Change can engender malignant sprawl, or healthy, orderly
growth.
v v
v
A broad consensus that objects emerge from an *iterative
incremental* evolutionary process has formed in the object-oriented
community over the last decade. See for instance [Booch 1994]. The [SOFTWARE
TECTONICS](../metamorphosis/metamorphosis.html#SoftwareTectonics) pattern [Foote & Yoder 1996] examines how systems can
incrementally cope with change.
The biggest risk associated with [PIECEMEAL
GROWTH](mud.html#PiecemealGrowth) is that it will gradually erode the overall structure of the
system, and inexorably turn it into a [BIG
BALL OF MUD](mud.html#BigBallOfMud). A strategy of [KEEPING
IT WORKING](mud.html#KeepItWorking) goes hand in hand with [PIECEMEAL
GROWTH](mud.html#PiecemealGrowth). Both patterns emphasize acute, local concerns at the expense
of chronic, architectural ones.
To counteract these forces, a permanent commitment to [CONSOLIDATION](../lifecycle/lifecycle.html#Consolidate) and
[refactoring](../lifecycle/lifecycle.html#Table2) must be
made. It is through such a process that local and global forces are
reconciled over time. This lifecyle perspective has been dubbed the *[fractal model](../frameworks/fractal.html)* [[Foote & Opdyke 1995](../lifecycle/lifecycle.html)]. To
quote Alexander [Brand 1994][Alexander 1988]:
*An organic process of growth and repair must create a gradual
sequence of changes, and these changes must be distributed evenly
across all levels of scale. [In developing a college campus] there
must be as much attention to the repair of details—rooms, wings
of buildings, windows, paths—as to the creation of brand new
buildings. Only then can the environment be balanced both as a whole,
and in its parts, at every moment in its history.*
| |
| --- |
|
**KEEP IT WORKING**
|
| |
| --- |
| *alias* |
| VITALITY |
| BABY STEPS |
| DAILY BUILD |
| FIRST, DO NO HARM |
Probably the greatest factor
that keeps us moving forward is that we use the system all the time,
and we keep trying to do new things with it. It is this
"living-with" which drives us to root out failures, to
clean up inconsistencies, and which inspires our occasional
innovation.
**Daniel H. H. Ingalls** [Ingalls
1983]
[![First, Do No Harm](../images/pictures/hippocrates.jpg)](http://kpt1.tricon.net/Personal/wesley/primum.html)
Once a city establishes its infrastructure, it is imperative
that it be kept working. For example, if the sewers break, and
aren’t quickly repaired, the consequences can escalate from
merely unpleasant to genuinely life threatening. People come to expect
that they can rely on their public utilities being available 24 hours
per day. They (rightfully) expect to be able to demand that an outage
be treated as an emergency.
v v
v
Software can be like this. Often a business becomes dependent
upon the data driving it. Businesses have become critically dependent
on their software and computing infrastructures. There are numerous
mission critical systems that must be on-the-air twenty-four hours a
day/seven days per week. If these systems go down, inventories can not
be checked, employees can not be paid, aircraft cannot be routed, and
so on.
There may be times where taking a system down for a major overhaul can
be justified, but usually, doing so is fraught with peril. However,
once the system is brought back up, it is difficult to tell which from
among a large collection of modifications might have caused a new
problem. Every change is suspect. This is why deferring such
integration is a recipe for misery. Capers Jones [Jones 1999] reported
that the chance that a significant change might contain a new error--a
phenomenon he ominously referred to as a *Bad Fix Injection*--
was about 7% in the United States. This may strike some readers as a
low figure. Still, it's easy to see that compounding this possibility
can lead to a situation where multiple upgrades are increasing likely
to break a system.
| |
| --- |
| **Maintenance needs have accumulated, but
an overhaul is unwise, since you might break the system.** |
*Workmanship:* Architects who live in the house they are building
have an obvious incentive to insure that things are done properly,
since they will directly reap the consequences when they do not. The
idea of the architect-builder is a central theme of Alexander's work.
Who better to resolve the forces impinging upon each design issue as
it arises as the person who is going to have to live with these
decisions? The architect-builder will be the direct beneficiary of his
or her own workmanship and care. Mistakes and shortcuts will merely
foul his or her own nest.
*Dependability:* These days, people rely on our software
artifacts for their very livelihoods, and even, at time, for their
very safety. It is imperative that ill-advise changes to elements of a
system do not drag the entire system down. Modern software systems are
intricate, elaborate webs of interdependent elements. When an
essential element is broken, everyone who depends on it will be
affected. Deadlines can be missed, and tempers can flare. This problem
is particularly acute in [BIG BALLS
OF MUD](mud.html#BigBallOfMud), since a single failure can bring the entire system down like
a house of cards.
| |
| --- |
| ***Therefore*, do what it
takes to maintain the software and keep it going. Keep it working.** |
When you are living in the system youre building, you have an
acute incentive not to break anything. A plumbing outage will be a
direct inconvenience, and hence you have a powerful reason to keep it
brief. You are, at times, working with live wires, and must exhibit
particular care. A major benefit of working with a live system is that
feedback is direct, and nearly immediate.
One of the strengths of this strategy is that modifications that break
the system are rejected immediately. There are always a large number
of paths forward from any point in a system’s evolution, and most
of them lead nowhere. By immediately selecting only those that do not
undermine the system’s viability, obvious dead-ends are avoided.
Of course, this sort of reactive approach, that of kicking the
nearest, meanest woolf from your door, is not necessarily globally
optimal. Yet, by eliminating obvious wrong turns, only more
insidiously incorrect paths remain. While these are always harder to
identify and correct, they are, fortunately less numerous than those
cases where the best immediate choice is also the best overall choice
as well.
It may seem that this approach only accommodates minor
modifications. This is not necessarily so. Large new subsystems might
be constructed off to the side, perhaps by separate teams, and
integrated with the running system in such a way as to minimize
distruption.
Design space might be thought of as a vast, dark, largely
unexplored forest. Useful potential paths through it might be thought
of as encompassing working programs. The space off to the sides of
these paths is much larger realm of non-working programs. From any
given point, a few small steps in most directions take you from a
working to a non-working program. From time to time, there are forks
in the path, indicating a choice among working alternatives. In
unexplored territory, the prudent strategy is never to stray too far
from the path. Now, if one has a map, a shortcut through the trekless
thicket that might save miles may be evident. Of course, pioneers, by
definition, don’t have maps. By taking small steps in any
direction, they know that it is never more than a few steps back to a
working system.
Some years ago, Harlan Mills
proposed that any software system should be grown by incremental
development. That is, the system first be made to run, even though it
does nothing useful except call the proper set of dummy subprograms.
Then, bit by bit, it is fleshed out, with the subprograms in turn
being developed into actions or calls to empty stubs in the level
below.
…
Nothing in the past decade has
so radically changed my own practice, and its effectiveness.
…
One always has, at every stage,
in the process, a working system. I find that teams can *grow*
much more complex entities in four months than they can *build.*
-- From "*No Silver
Bullet"* [Brooks 1995]
Microsoft mandates that a DAILY BUILD of each product be
performed at the end of each working day. Nortel adheres to the
slightly less demanding requirement that a working build be generated
at the end of each week [Brooks 1995][Cusumano & Shelby 1995].
Indeed, this approach, and keeping the last working version around,
are nearly universal practices among successful maintenance
programmers.
Another vital factor in ensuring a system's continued vitality
is a commitment to rigorous testing [Marick 1995][Bach 1994]. It's
hard to keep a system working if you don't have a way of making sure
it works. Testing is one of pillars of Extreme Programming. XP
practices call for the development of unit tests before a single line
of code is written.
v v
v
Always beginning with a working system helps to encourage [PIECEMEAL GROWTH](mud.html#PiecemealGrowth). Refactoring is
the primary means by which programmers maintain order from inside the
systems in which they are working. The goal of refactoring is to leave
a system working as well after a refactoring as it was before the
refactoring. Aggressive unit and integration testing can help to
guarantee that this goal is met.
| |
| --- |
|
**SHEARING LAYERS**
|
[![Hummingbird](../images/pictures/hummingbird.jpg)](http://www.corbis.com)
Hummingbirds and flowers are
quick, redwood trees are slow, and whole redwood forests are even
slower. Most interaction is within the same pace level--hummingbirds
and flowers pay attention to each other, oblivious to redwoods, who
are oblivious to them.
**R. V. O'Neill** , *A
Hierarchical Concept of Ecosystems*
The notion of [SHEARING LAYERS](mud.html#ShearingLayers) is
one of the centerpieces of Brand's *How Buildings Learn* [Brand
1994]. Brand, in turn synthesized his ideas from a variety of sources,
including British designer Frank Duffy, and ecologist R. V. O'Neill.
[![Brand, Page 13](../images/figures/shearing-small.gif)](../images/figures/shearing-layers.gif)
Brand quotes Duffy as saying: "Our basic argument is that there
isn't any such thing as a building. A building properly conceived is
several layers of longevity of built components".
Brand distilled Duffy's proposed layers into these six: Site,
Structure, Skin, Services, Space Plan, and Stuff. Site is geographical
setting. Structure is the load bearing elements, such as the
foundation and skeleton. Skin is the exterior surface, such as siding
and windows. Services are the circulatory and nervous systems of a
building, such as its heating plant, wiring, and plumbing. The Space
Plan includes walls, flooring, and ceilings. Stuff includes lamps,
chairs, appliances, bulletin boards, and paintings.
These layers change at different rates. Site, they say, is
eternal. Structure may last from 30 to 300 years. Skin lasts for
around 20 years, as it responds to the elements, and to the whims of
fashion. Services succumb to wear and technical obsolescence more
quickly, in 7 to 15 years. Commercial Space Plans may turn over every
3 years. Stuff, is, of course, subject to unrelenting flux [Brand
1994].
v v
v
Software systems cannot stand still. Software is often called upon to
bear the brunt of changing requirements, because, being as that it is
made of bits, it can change.
| |
| --- |
| **Different artifacts change
at different rates.** |
*Adaptability:* A system that can cope readily with a wide range
of requirements, will, all other things being equal, have an advantage
over one that cannot. Such a system can allow unexpected requirements
to be met with little or no reengineering, and allow its more skilled
customers to rapidly address novel challenges.
*Stability:* Systems succeed by doing what they were designed to
do as well as they can do it. They earn their niches, by bettering
their competition along one or more dimensions such as cost, quality,
features, and performance. See [[Foote
& Roberts 1998](../lingua/lingua.html)] for a discussion of the occasionally fickle nature of
such completion. Once they have found their niche, for whatever
reason, it is essential that short term concerns not be allowed to
wash away the elements of the system that account for their mastery of
their niche. Such victories are inevitably hard won, and fruits of
such victories should not be squandered. Those parts of the system
that do what the system does well must be protected from fads, whims,
and other such spasms of poor judgement.
*Adaptability* and *Stability* are forces that are in
constant tension. On one hand, systems must be able to confront
novelty without blinking. On the other, they should not squander their
patrimony on spur of the moment misadventures.
| |
| --- |
| ***Therefore*, factor your
system so that artifacts that change at similar rates are together.** |
Most interactions in a system tend to be within layers, or between
adjacent layers. Individual layers tend to be about things that change
at similar rates. Things that change at different rates diverge.
Differential rates of change encourage layers to emerge. Brand notes
as well that occupational specialties emerge along with these layers.
The rate at which things change shapes our organizations as well. For
instance, decorators and painters concern themselves with interiors,
while architects dwell on site and skin. We expect to see things that
evolve at different rates emerge as distinct concerns. This is ["separate
that which changes from that which doesn't"](http://st-www.cs.uiuc.edu/~droberts/evolve.html#SeparateChangeable) [[Roberts
& Johnson 1998](http://st-www.cs.uiuc.edu/~droberts/evolve.html)] writ large.
Can we identify such layers in software?
Well, at the bottom, there are data. Things that change most
quickly migrate into the data, since this is the aspect of software
that is most amenable to change. Data, in turn, interact with users
themselves, who produce and consume them.
Code changes more slowly than data, and is the realm of
programmers, analysts and designers. In object-oriented languages,
things that will change quickly are cast as black-box polymorphic
components. Elements that will change less often may employ white-box
inheritance.
The abstract classes and components that constitute an
object-oriented framework change more slowly than the applications
that are built from them. Indeed, their role is to distill what is
common, and enduring, from among the applications that seeded the
framework.
As frameworks evolve, certain abstractions make their ways from
individual applications into the frameworks and libraries that
constitute the system's infrastructure [[Foote 1988](../dfc/discussion.html)]. Not all elements will
make this journey. Not all should. Those that do are among the most
valuable legacies of the projects that spawn them. Objects help
shearing layers to emerge, because they provide places where more
fine-grained chunks of code and behavior that belong together can
coalesce.
The Smalltalk programming language is built from a set of
objects that have proven themselves to be of particular value to
programmers. Languages change more slowly than frameworks. They are
the purview of scholars and standards committees. One of the
traditional functions of such bodies is to ensure that languages
evolve at a suitably deliberate pace.
Artifacts that evolve quickly provide a system with dynamism and
flexibility. They allow a system to be fast on its feet in the face of
change.
Slowly evolving objects are bulwarks against change. They embody
the wisdom that the system has accrued in its prior interactions with
its environment. Like tenure, tradition, big corporations, and
conservative politics, they maintain what has worked. They worked
once, so they are kept around. They had a good idea once, so maybe
they are a better than even bet to have another one.
Wide acceptance and deployment causes resistance to change. If
changing something will break a lot of code, there is considerable
incentive not to change it. For example, schema reorganization in
large enterprise databases can be an expensive and time-consuming
process. Database designers and administrators learn to resist change
for this reason. Separate job descriptions, and separate hardware,
together with distinct tiers, help to make these tiers distinct.
The phenomenon whereby distinct concerns emerge as distinct
layers and tiers can be seen as well with graphical user interfaces.
Part of the impetus behind using [METADATA](../metadata/metadata.html#Metadata) [[Foote & Yoder 1998b](../metadata/metadata.html)] is the
observation that pushing complexity and power into the data pushes
that same power (and complexity) out of the realm of the programmer
and into the realm of users themselves. Metadata are often used to
model static facilities such as classes and schemas, in order to allow
them to change dynamically. The effect is analogous to that seen with
modular office furniture, which allows office workers to easily,
quickly, and cheaply move partitions without having to enlist
architects and contractors in the effort.
Over time, our frameworks, abstract classes, and components come
to embody what we've learned about the structure of the domains for
which they are built. More enduring insights gravitate towards the
primary structural elements of these systems. Things which find
themselves in flux are spun out into the data, where users can
interact with them. Software evolution becomes like a centrifuge spun
by change. The layers that result, over time, can come to a much truer
accommodation with the forces that shaped them than any top-down
agenda could have devised.
Things that are good have a
certain kind of structure. You cant get that structure except
dynamically. Period. In nature youve got continuous
very-small-feedback-loop adaptation going on, which is why things get
to be harmonious. Thats why they have the qualities we value. If it
wasnt for the time dimension, it wouldnt happen. Yet here we are
playing the major role creating the world, and we havent figured
this out. That is a very serious matter.
**Christopher Alexander** --
[Brand 1994]
[![Redwood](../images/pictures/redwood.jpg)](http://sregora.com/gallery/cagallery.html)
v v
v
This pattern has much in common with the [HOT
SPOTS](http://st-www.cs.uiuc.edu/~droberts/evolve.html#SeparateChangeable) pattern discussed in [[Roberts
& Johnson 1998](http://st-www.cs.uiuc.edu/~droberts/evolve.html)]. Indeed, separating things that change from those
that do not is what drives the emergence of [SHEARING LAYERS](mud.html#ShearingLayers). These [layers](http://www.rational.com/products/whitepapers/390.jsp#page=11) are the result of such differential rates of change, while [HOT
SPOTS](http://st-www.cs.uiuc.edu/~droberts/evolve.html#SeparateChangeable) might be thought of as the rupture zones in the fault lines
along which slippage between layers occurs. This tectonic slippage is
suggestive as well of the [SOFTWARE
TECTONICS](../metamorphosis/metamorphosis.html#SoftwareTectonics) pattern [[Foote
& Yoder 1996](../metamorphosis/metamorphosis.html)], which recommends fine-grained iteration as a means
of avoiding catastrophic upheaval. [METADATA](../metadata/metadata.html#Metadata) and [ACTIVE
OBJECT-MODELS](../metadata/metadata.html#ActiveObjectModel) [[Foote &
Yoder 1998b](../metadata/metadata.html)] allow systems to adapt more quickly to changing
requirements by [pushing
power](http://www.joeyoder.com/~yoder/Research/metadata/OOPSLA98MetaDataWkshop.html) into the data, and out onto users.
| |
| --- |
|
**SWEEPING IT UNDER THE
RUG**
|
| |
| --- |
| *alias* |
| POTEMKIN VILLAGE |
| HOUSECLEANING |
| PRETTY FACE |
| QUARANTINE |
| HIDING IT UNDER THE BED |
| REHABILITATION |
[![Concrete Sarcophagus](../images/pictures/reactor4-shirley.gif)](http://www.ic-chernobyl.kiev.ua/index.html)
One of the most spectacular
examples of *sweeping a problem under the rug* is the
concrete sarcophagus that Soviet engineers constructed to put a
10,000 year lid on the infamous [reactor
number four](http://polyn.net.kiae.su/polyn/head_ill.html) at [Chernobyl](http://www.kingroach.com/comics/chernobyl.html),
in what is now Ukraine.
If you can’t make a mess go away, at least you can hide it.
Urban renewal can begin by painting murals over graffiti and putting
fences around abandoned property. Children often learn that a single
heap in the closet is better than a scattered mess in the middle of
the floor.
v v
v
There are reasons, other than aesthetic concerns, professional
pride, and guilt for trying to clean up messy code. A deadline may be
nearing, and a colleague may want to call a chunk of your code, if you
could only come up with an interface through which it could be called.
If you don’t come up with an easy to understand interface,
they’ll just use someone else’s (perhaps inferior) code. You
might be cowering during a code-review, as your peers trudge through a
particularly undistinguished example of your work. You know that there
are good ideas buried in there, but that if you don’t start to
make them more evident, they may be lost.
There is a limit to how much chaos an individual can tolerate before
being overwhelmed. At first glance, a [BIG
BALL OF MUD](mud.html#BigBallOfMud) can inspire terror and despair in the hearts of those who
would try to tame it. The first step on the road to architectural
integrity can be to identify the disordered parts of the system, and
isolate them from the rest of it. Once the problem areas are
identified and hemmed in, they can be gentrified using a divide and
conquer strategy.
| |
| --- |
| **Overgrown, tangled,
haphazard spaghetti code is hard to comprehend, repair, or extend,
and tends to grow even worse if it is not somehow brought under
control.** |
[![The Bondage of Gulliver](../images/pictures/threads-small.jpg)](http://www.jaffebros.com/lee/gulliver/prittie/cover.jpeg)
*Comprehensibility:* It should go without saying that
comprehensible, attractive, well-engineered code will be easier to
maintain and extend than complicated, convoluted code. However, it
takes *Time* and money to overhaul sloppy code. Still, the *Cost*
of allowing it to fester and continue to decline should not be
underestimated.
*Morale:* Indeed, the price of life with a [BIG BALL OF MUD](mud.html#BigBallOfMud) goes beyond the
bottom line. Life in the muddy trenches can be a dispiriting fate.
Making even minor modifications can lead to maintenance marathons.
Programmers become timid, afraid that tugging at a loose thread may
have unpredictable consequences. After a while, the myriad [threads](../images/pictures/gulliver-threads.jpg) that
couple every part of the system to every other come to tie the
programmer down as surely as [Gulliver](http://www.jaffebros.com/lee/gulliver/) among the
[Lilliputians](http://www.jaffebros.com/lee/gulliver/bk1/index.html)
[[Swift
1726](http://www.jaffebros.com/lee/gulliver/contents.html)]. Talent may desert the project in the face of such bondage.
It should go without saying that comprehensible, attractive,
well-engineered code will be easier to maintain and extend than
complicated, convoluted code. However, it takes time and money to
overhaul sloppy code. Still, the cost of allowing it to fester and
continue to decline should not be underestimated.
| |
| --- |
| ***Therefore*, if you
can’t easily make a mess go away, at least cordon it off. This
restricts the disorder to a fixed area, keeps it out of sight, and
can set the stage for additional refactoring.** |
By getting the dirt into a single pile beneath the carpet, you
at least know where it is, and can move it around. You’ve still
got a pile of dirt on your hands, but it is localized, and your guests
can’t see it. As the engineers who entombed reactor number four
at Chernobly demonstrated, sometimes you've got to get a lid on a
problem before you can get serious about cleaning things up. Once the
problem area is contained, you can decontaminate at a more leisurely
pace.
[![Urban Decay](../images/pictures/urban-decay-small.jpg)](http://www.pathfinder.com/@@z04;c6PyNAIAQH2x/photo/archive/themes/urban.htm)
To begin to get a handle on spaghetti code, find those sections
of it that seem less tightly coupled, and start to draw architectural
boundaries there. Separate the global information into distinct data
structures, and enforce communication between these enclaves using
well-defined interfaces. Such steps can be the first ones on the road
to re-establishing the system’s conceptual integrity, and
discerning nascent architectural landmarks.
Putting a fresh interface around a run down region of the system can
be the first step on the way architectural rehabilitation. This is a
long row to hoe, however. Distilling meaningful abstractions from a [BIG BALL OF MUD](mud.html#BigBallOfMud) is a difficult and
demand task. It requires skill, insight, and persistence. At times, [RECONSTRUCTION](mud.html#Reconstruction) may seem like the
less painful course. Still, it is not like unscrambling an egg. As
with rehabilitation in the real world, restoring a system to
architectural health requires resources, as well as a sustained
commitment on the part of the people who live there.
The UIMX user interface builder for Unix and Motif, and the
various Smalltalk GUI builders both provide a means for programmers to
cordon off complexity in this fashion.
v v
v
One frequently constructs a [FAÇADE](http://ksi.cpsc.ucalgary.ca/~kremer/patterns/facade.html)
[Gamma et. al. 1995] to put a [congenial](http://www.m-w.com/cgi-bin/dictionary?congenial)
"pretty face" on the unpleasantness that is [SWEPT UNDER THE RUG](mud.html#SweepingItUnderTheRug). Once
these messy chunks of code have been quarantined, you can expose their
functionality using INTENTION REVEALING SELECTORS [Beck 1997].
This can be the first step on the road to [CONSOLIDATION](../lifecycle/lifecycle.html#Consolidate) too,
since one can begin to hem in unregulated growth than may have
occurred during [PROTOTYPING](../lifecycle/lifecycle.html#Prototype)
or [EXPANSION](../lifecycle/lifecycle.html#Expand) [[Foote & Opdyke 1995](../lifecycle/lifecycle.html)]. [[Foote & Yoder 1998a](../selfish/selfish.html)] explores
how, ironically, inscrutable code can persist because it is
difficult to comprehend.
This paper also examines how complexity can be hidden using suitable
defaults ([WORKS
OUT OF THE BOX](../selfish/selfish.html#WorksOutOfTheBox) and [PROGRAMMING-BY-DIFFERRENCE](../selfish/selfish.html#ProgrammingByDifference)),
and interfaces that gradually reveal additional capabilities as the
client grows more sophisticated.
| |
| --- |
|
**RECONSTRUCTION**
|
| |
| --- |
| *alias* |
| TOTAL REWRITE |
| DEMOLITION |
| THROWAWAY THE FIRST ONE |
| START OVER |
[![Fulton County Stadium Demolition](../images/pictures/atlanta/stadium.jpg)](../images/movies/fcs_demolition_26sec.mov)
Atlanta’s Fulton County Stadium was built in 1966 to serve
as the home of baseball’s Atlanta Braves, and football’s
Atlanta Falcons. In August of 1997, the stadium was demolished. Two
factors contributed to its relatively rapid obsolescence. One was that
the architecture of the original stadium was incapable of
accommodating the addition of the "sky-box" suites that the
spreadsheets of ‘90s sporting economics demanded. No conceivable
retrofit could accommodate this requirement. Addressing it meant
starting over, from the ground up. The second was that the
stadium’s attempt to provide a cheap, general solution to the
problem of providing a forum for both baseball and football audiences
compromised the needs of both. In only thirty-one years, the balance
among these forces had shifted decidedly. The facility is being
replaced by two new single-purpose stadia.
Might there be lessons for us about unexpected requirements and
designing general components here?
v v
v
*Plan to Throw One Away
(You Will Anyway)* -- Brooks
Extreme Programming [Beck 2000] had its genesis in the Chrysler
Comprehensive Compensation project (C3). It began with a cry for help
from a foundering project, and a decision to discard a year and a
half's worth of work. The process they put in place after they started
anew laid the foundation for XP, and the author's credit these
approaches for the subsequent success of the C3 effort. However, less
emphasis is given to value of the experience the team might have
salvaged from their initial, unsuccessful draft. Could this first
draft have been the unsung hero of this tale?
| |
| --- |
| **Your code has declined to
the point where it is beyond repair, or even comprehension.** |
*Obsolescence*: Of course, one reason to abandon a system is that
it is in fact technically or economically obsolete. These are distinct
situations. A system that is no longer state-of-the-art may still sell
well, while a technically superior system may be overwhelmed by a more
popular competitor for non-technical reasons.
In the realm of concrete and steel, blight is the symptom, and a
withdrawal of capital is the cause. Of course, once this process
begins, it can feed on itself. On the other hand, given a steady
infusion of resources, buildings can last indefinitely. It's not
merely entropy, but an unwillingness to counteract it, that allows
buildings to decline. In Europe, neighborhoods have flourished for
hundreds of years. They have avoided the boom/bust cycles that
characterize some New World cities.
*Change:* Even though software is a highly malleable medium, like
Fulton County Stadium, new demands can, at times, cut across a
system’s architectural assumptions in such a ways as to make
accommodating them next to impossible. In such cases, a total rewrite
might be the only answer.
*Cost*: Writing-off a system can be traumatic, both to those who
have worked on it, and to those who have paid for it. Software is
often treated as an asset by accountants, and can be an expensive
asset at that. Rewriting a system, of course, does not discard its
conceptual design, or its staff’s experience. If it is truly the
case that the value of these assets is in the design experience they
embody, then accounting practices must recognize this.
*Organization:* Rebuilding a system from scratch is a
high-profile undertaking, that will demand considerable time and
resources, which, in turn, will make high-level management support
essential.
| |
| --- |
| ***Therefore*, throw it away
and start over.** |
Sometimes it’s just easier to throw a system away, and
start over. Examples abound. Our shelves are littered with the
discarded carcasses of obsolete software and its documentation.
Starting over can be seen as a defeat at the hands of the old code, or
a victory over it.
[![Pruitt-Igoe](../images/pictures/pruitt3.jpg)](http://www.sheridanc.on.ca/~randy/design.dir/disaster.dir/disaster.htm)
One reason to start over might be that the previous system was
written by people who are long gone. Doing a rewrite provides new
personnel with a way to reestablish contact between the architecture
and the implementation. Sometimes the only way to understand a system
it is to write it yourself. Doing a fresh draft is a way to overcome
neglect. Issues are revisited. A fresh draft adds vigor. You draw back
to leap. The quagmire vanishes. The swamp is drained.
Another motivation for building a new system might be that you
feel that you've got the experience you need to do the job properly.
One way to have gotten this experience is to have participated at some
level in the unsuccessful development of a previous version of the
system.
Of course, the new system is not designed in a vacuum.
Brook’s famous tar pit is excavated, and the fossils are
examined, to see what they can tell the living. It is essential that a
thorough post-mortem review be done of the old system, to see what it
did well, and why it failed. Bad code can bog down a good design. A
good design can isolate and contain bad code.
When a system becomes a [BIG BALL
OF MUD](mud.html#BigBallOfMud), its relative incomprehensibility may hasten its demise, by
making it difficult for it to adapt. It can persist, since it resists
change, but cannot evolve, for the same reason. Instead, its
inscrutability, even when it is to its s hort-term benefit, sows the
seeds of its ultimate demise.
If this makes muddiness a frequently terminal condition, is this
really a bad thing? Or is it a blessing that these sclerotic systems
yield the stage to more agile successors? Certainly, the departure of
these ramshackle relics can be a cause for celebration as well as
sadness.
[![Cheshire Cat](../images/pictures/chcat1.gif)](http://www.webslingerz.com/~jhoffman/chcat.html)
Discarding a system dispenses with its implementation, and
leaves only its conceptual design behind. Only the patterns that
underlie the system remain, grinning like a Cheshire cat. It is their
spirits that help to shape the next implementation. With luck, these
architectural insights will be reincarnated as genuine reusable
artifacts in the new system, such as abstract classes and frameworks.
It is by finding these architectural nuggets that the promise of
objects and reuse can finally be fulfilled.
There are alternatives to throwning your system away and starting
over. One is to embark on a regimen of incremental refactoring, to
glean architectural elements and discernable abstractions from the
mire. Indeed, you can begin by looking for coarse fissures along which
to separate parts of the system, as was suggested in [SWEEPING IT UNDER THE RUG](mud.html#SweepingItUnderTheRug).
Of course, refactoring is more effective as a prophylactic measure
that as a last-restort therapy. As with any edifice, it is a judgement
call, whether to rehab or restort for the wrecking ball. Another
alternative is to reassess whether new components and frameworks have
come along that can replace all or part of the system. When you can
reuse and retrofit other existing components, you can spare yourself
the time and expense involved in rebuilding, repairing, and
maintaining the one you have.
The United States Commerce Department defines *durable goods* as
those that are designed to last for three years or more. This category
traditionally applied to goods such as furniture, appliances,
automobiles, and business machines. Ironically, as computer equipment
is depreciating ever more quickly, it is increasingly our software
artifacts, and not our hardware, that fulfill this criterion. Firmitas
has come to the realm of bits and bytes.
Apple's Lisa Toolkit, and its successor, the Macintosh Toolbox,
constitute one of the more intriguing examples of
[RECONSTRUCTION](mud.html#Reconstruction) in the history of
personal computing.
*An architect's most
useful tools are an eraser at the drafting board, and a wrecking bar
at the site*
-- Frank Lloyd Wright
v v
v
The [SOFTWARE
TECTONICS](../metamorphosis/metamorphosis.html#SoftwareTectonics) pattern discussed in [Foote & Yoder 1996] observes that
if incremental change is deferred indefinitely, major upheaval may be
the only alternative. [Foote & Yoder 1998a] explores the [WINNING TEAM](../selfish/selfish.html#WinningTeam)
phenomenon, whereby otherwise superior technical solutions are
overwhelmed by non-technical [exigencies](http://www.m-w.com/cgi-bin/dictionary?exigencies).
[Brooks](http://www.yourdon.com/books/coolbooks/notes/brooks.html)
has eloquently observed that the most dangerous system an architect
will ever design is his or her [second
system](http://www.realtime-info.be/encyc/techno/terms/51/81.htm) [Brooks 1995]. This is the notorious [second-system
effect](http://www.elsewhere.org/jargon_search/TAG1571.html). [RECONSTRUCTION](mud.html#Reconstruction) provides
an opportunity for this misplaced hubris to exercise itself, so one
must keep a wary eye open for it. Still, there are times when the best
and only way to make a system better is to throw it away and start
over. Indeed, one can do worse than to heed Brook's classic admonition
that you should "plan to throw one away, you will anyway".
![Mir over Fiji](../images/pictures/fiji.jpg)
*Mir reenters the atmosphere over Fiji on 22 March, 2001*
| |
| --- |
|
**Conclusion**
|
In the end, software architecture is about how we distill experience
into wisdom, and disseminate it. We think the patterns herein stand
alongside other work regarding software architecture and evolution
that we cited as we went along. Still, we do not consider these
patterns to be anti-patterns. There are good reasons that good
programmers build [BIG BALLS OF MUD](mud.html#BigBallOfMud).
It may well be that the economics of the software world are such that
the market moves so fast that long term architectural ambitions are
foolhardy, and that expedient, slash-and-burn, disposable programming
is, in fact, a state-of-the-art strategy. The success of these
approaches, in any case, is undeniable, and seals their pattern-hood.
People build
[BIG BALLS OF MUD](mud.html#BigBallOfMud) because they work.
In many domains, they are the only things that have been shown to
work. Indeed, they work where loftier approaches have yet to
demonstrate that they can compete.
It is not our purpose to condemn [BIG
BALLS OF MUD](mud.html#BigBallOfMud). Casual architecture is natural during the early stages
of a system’s evolution. The reader must surely suspect, however,
that our hope is that we can aspire to do better. By recognizing the
forces and pressures that lead to architectural malaise, and how and
when they might be confronted, we hope to set the stage for the
emergence of truly durable artifacts that can put architects in
dominant positions for years to come. The key is to ensure that the
system, its programmers, and, indeed the entire organization, *learn*
about the domain, and the architectural opportunities looming within
it, as the system grows and matures.
Periods of moderate disorder are a part of the ebb and flow of
software evolution. As a master chef tolerates a messy kitchen,
developers must not be afraid to get a little mud on their shoes as
they explore new territory for the first time. Architectural insight
is not the product of master plans, but of hard won experience. The
software architects of yesteryear had little choice other than to
apply the lessons they learned in successive drafts of their systems,
since [RECONSTRUCTION](mud.html#Reconstruction) was often
the only practical means they had of supplanting a mediocre system
with a better one. Objects, frameworks, components, and refactoring
tools provide us with another alternative. Objects present a medium
for expressing our architectural ideas at a level between
coarse-grained applications and components and low level code.
Refactoring tools and techniques finally give us the means to
cultivate these artifacts as they evolve, and capture these insights.
The onion-domed *Church of the Intercession of the Virgin on the
Moat* in Moscow is one of Russia's most famous landmarks. It was built
by Tsar Ivan IV just outside of the Kremlin walls in 1552 to
commemorate Russia's victory over the Tatars at Kazan. The church is
better known by it's nickname, St. Basil's. Ivan too is better known
by his nickname "Ivan the Terrible". Legend has it that once the
cathedral was completed, Ivan, ever true to his reputation, had the
architects blinded, so that they could never build anything more
beautiful. Alas, the state of software architecture today is such that
few of us need fear for our eyesight.
[![St. Basil's](../images/pictures/basils.jpg)](http://www.gac.edu/Academics/russian/www-docs/Architecture_HTML/page_id_6881.html)
| |
| --- |
|
**Acknowledgments**
|
A lot of people have striven to help us avoid turning this paper into
an unintentional example of its central theme. We are grateful first
of all to the members of the [University of
Illinois Software Architecture Group](http://st-www.cs.uiuc.edu/research-gp.html), [John Brant](http://st-www.cs.uiuc.edu/~brant), [Ian Chai](http://st-www.cs.uiuc.edu/~chai), [Ralph Johnson](http://st-www.cs.uiuc.edu/users/johnson/),
Lewis Muir, [Dragos
Manolescu](http://www.ncsa.uiuc.edu/people/daman/), [Brian
Marick](http://www.stlabs.com/marick/root.htm), Eiji Nabika, [John
(Zhijiang) Han](http://www.ews.uiuc.edu/~zhan1/), Kevin Scheufele, Tim Ryan, Girish Maiya, Weerasak
Wittawaskul, Alejandra Garrido, Peter Hatch, and [Don Roberts](http://chip.cs.uiuc.edu/~droberts), who
commented on several drafts of this work over the last three years.
We’d like to also thank our tireless shepherd, Bobby Woolf,
who trudged through the muck of several earlier versions of this
paper.
Naturally, we’d like to acknowledge the members of our PLoP
’97 Conference Writer’s Workshop, Norm Kerth, Hans Rohnert,
Clark Evans, Shai Ben-Yehuda, Lorraine Boyd, Alejandra Garrido, [Dragos Manolescu](http://www.ncsa.uiuc.edu/people/daman/),
Gerard Meszaros, Kyle Brown, [Ralph Johnson](http://st-www.cs.uiuc.edu/users/johnson/),
and Klaus Renzel.
Lorrie Boyd provided some particularly poignant observations on
scale, and the human cost of projects that fail.
UIUC Architecture professor Bill Rose provided some keen
insights on the durability of housing stock, and history of the
estrangement of architects from builders.
Thanks to [Brad
Appleton](http://www.enteract.com/~bradapp/), [Michael
Beedle](http://www.fti-consulting.com/users/beedlem/), Russ Hurlbut, and the rest of the people in the [Chicago
Patterns Group](http://c2.com/cgi/wiki?ChicagoPatternsGroup) for their time, suggestions, and ruminations on reuse
and reincarnation.
Thanks to [Steve Berczuk](http://world.std.com/~berczuk/ )
and the members of the [Boston Area
Patterns Group](http://c2.com/cgi/wiki?BostonAreaPatternsGroup) for their review.
Thanks too to [Joshua
Kerievsky](http://www.industriallogic.com/) and the [Design
Patterns Study Group of New York City](http://www.industriallogic.com/patterns/index.html) for their comments.
We'd like to express our gratitude as well to Paolo Cantoni, Chris
Olufson, Sid Wright, John Liu, Martin Cohen, John Potter, Richard
Helm, and [James Noble](http://www.mri.mq.edu.au/~kjx/) of
the [Sydney
Patterns Group](http://www.mri.mq.edu.au/~kjx/patterns/), who workshopped this paper during the late winter,
er, summer of early 1998.
John Vlissides, Neil Harrison, Hans Rohnert, James Coplien, and [Ralph Johnson](http://st-www.cs.uiuc.edu/users/johnson/)
provided some particularly candid, incisive and useful criticism of
some of the later drafts of the paper.
A number of readers have observed, over the years, that [BIG BALL OF MUD](mud.html#BigBallOfMud) has a certain [dystopian](http://www.m-w.com/cgi-bin/dictionary?dystopian),
Dilbert-esque quality to it. We are grateful to [United Features Syndicate, Inc.](http://www.dilbert.com/)
for not having, as of yet, asked us to remove the following cartoon
from the web-based version of [BIG
BALL OF MUD](mud.html#BigBallOfMud).
[![Dilbert -- 6 April 1990](../images/pictures/elbonia-900406.gif)](http://www.zippah.com/~dtweed/dilbert/w0726866.htm)
| |
| --- |
|
**References**
|
```
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Christopher Alexander
***Notes on the Synthesis of Form***
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Christopher Alexander
***The Timeless Way of Building***
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**[Alexander et. al 1977]**
C. Alexander, S. Ishikawa, and M. Silverstein
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Christopher Alexander
***The Oregon Experiment***
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Kent Beck and [Ward Cunningham](http://www.c2.com/doc/index.html)
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[James O. Coplien](http://www.bell-labs.com/people/cope/)
***[A Generative Development-Process Pattern Language](http://www.bell-labs.com/user/cope/Patterns/Process/index.html)***
First Conference on Pattern Languages of Programs (PLoP '94)
Monticello, Illinois, August 1994
[Pattern Languages of Program Design](http://www.bell-labs.com/topic/books/PLoPD1/)
edited by James O. Coplien and Douglas C. Schmidt
[Addison-Wesley](http://cseng.aw.com/bookdetail.qry?ISBN=0-201-60734-4&ptype=0), 1995
**[Cunningham 1999a]**
[Ward Cunningham](http://c2.com)
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<http://www.c2.com/cgi/wiki?PeterPrincipleProgramming>
**[Cunningham 1999b]**
[Ward Cunningham](http://c2.com)
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Michael A. Cusumano and Richard W. Shelby
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The Free Press, New York, NY, 1995
**[Foote 1988]**
[Brian Foote](mud.html#BrianFoote) (Advisor: [Ralph Johnson](http://st-www.cs.uiuc.edu/users/johnson/))
***[Designing to Facilitate Change with Object-Oriented Frameworks](../dfc/discussion.html)***
[Masters Thesis](../dfc/DFC.html), [1988](http://www.laputan.com/cgi-bin/calendar?1988)
[Dept. of Computer Science](http://www.cs.uiuc.edu/),
[University of Illinois at Urbana-Champaign](http://www.uiuc.edu/)
**[Foote & Opdyke 1995]**
[Brian Foote](mud.html#BrianFoote) and William F. Opdyke
***[Lifecycle and Refactoring Patterns that Support Evolution and Reuse](../lifecycle/lifecycle.html)***
First Conference on Patterns Languages of Programs (PLoP '94)
Monticello, Illinois, August 1994
[Pattern Languages of Program Design](http://cseng.aw.com/bookdetail.qry?ISBN=0-201-60734-4&ptype=0)
edited by [James O. Coplien](http://www.bell-labs.com/people/cope/) and [Douglas C. Schmidt](http://www.cs.wustl.edu/~schmidt/)
[Addison-Wesley](http://www.awl.com/cseng/index.html), [1995](http://www.laputan.com/cgi-bin/calendar?1995)
This volume is part of the [Addison-Wesley Software Patterns Series](http://cseng.aw.com/seriesdetail.qry?SeriesID=34).
**[Foote & Yoder 1996]**
[Brian Foote](mud.html#BrianFoote) and [Joseph W. Yoder](http://www.joeyoder.com/)
***[Evolution, Architecture, and Metamorphosis](../metamorphosis/metamorphosis.html)***
Second Conference on Patterns Languages of Programs (PLoP '95)
Monticello, Illinois, September 1995
[Pattern Languages of Program Design 2](http://cseng.aw.com/bookdetail.qry?ISBN=0-201-89527-7&ptype=0)
edited by [John M. Vlissides](http://www.software.ibm.com/qawww/despat-expert.html), [James O. Coplien](http://www.bell-labs.com/people/cope/), and Norman L. Kerth
[Addison-Wesley](http://www.awl.com/cseng/index.html), [1996](http://www.laputan.com/cgi-bin/calendar?1996)
This volume is part of the [Addison-Wesley Software Patterns Series](http://cseng.aw.com/seriesdetail.qry?SeriesID=34).
**[Foote & Roberts 1998]**
[Brian Foote](mud.html#BrianFoote) and [Don Roberts](http://chip.cs.uiuc.edu/~droberts/)
***[Lingua Franca](../lingua/lingua.html)***
[Fifth Conference on Patterns Languages of Programs](http://st-www.cs.uiuc.edu/~berczuk/PLoP98/) ([PLoP '98](http://jerry.cs.uiuc.edu/~plop/plop98/final_submissions/))
Monticello, Illinois, [August 1998](http://www.laputan.com/cgi-bin/calendar?8+1998)
Technical Report #WUCS-98-25 ([PLoP '98](http://jerry.cs.uiuc.edu/~plop/plop98/final_submissions/)/[EuroPLoP '98](http://www.coldewey.com/europlop98/Program/writers.htm)), [September 1998](http://www.laputan.com/cgi-bin/calendar?9+1998)
[Department of Computer Science](http://www.cs.wustl.edu/), [Washington University](http://www.wustl.edu)
**[Foote & Yoder 1996]**
[Brian Foote](mud.html#BrianFoote) and [Joseph W. Yoder](http://www.joeyoder.com/)
***[Evolution, Architecture, and Metamorphosis](../metamorphosis/metamorphosis.html)***
Second Conference on Patterns Languages of Programs (PLoP '95)
Monticello, Illinois, September 1995
[Pattern Languages of Program Design 2](http://cseng.aw.com/bookdetail.qry?ISBN=0-201-89527-7&ptype=0)
edited by [John M. Vlissides](http://www.software.ibm.com/qawww/despat-expert.html), [James O. Coplien](http://www.bell-labs.com/people/cope/), and Norman L. Kerth
[Addison-Wesley](http://heg-school.aw.com/cseng/index.html), [1996](http://www.laputan.com/cgi-bin/calendar?1996)
This volume is part of the [Addison-Wesley Software Patterns Series](http://cseng.aw.com/seriesdetail.qry?SeriesID=34).
**[Foote & Yoder 1998a]**
[Brian Foote](mud.html#BrianFoote) and [Joseph W. Yoder](http://www.joeyoder.com/)
***[The Selfish Class](../selfish/selfish.html)***
Third Conference on Patterns Languages of Programs ([PLoP '96](http://www.cs.wustl.edu/~schmidt/jointPLoP-96.html))
Monticello, Illinois, [September 1996](http://www.laputan.com/cgi-bin/calendar?9+1996)
[Technical Report #WUCS-97-07](http://www.cs.wustl.edu/~schmidt/PLoP-96/program.html), [September 1996](http://www.laputan.com/cgi-bin/calendar?9+1996)
[Department of Computer Science](http://www.cs.wustl.edu/), [Washington University](http://www.wustl.edu)
[Pattern Languages of Program Design 3](http://cseng.aw.com/bookdetail.qry?ISBN=0-201-31011-2&ptype=0)
edited by [Robert Martin](http://www.oma.com./Brochure/Resumes/rmartin.html), [Dirk Riehle](http://www.riehle.org/), and Frank Buschmann
[Addison-Wesley](http://www.awl.com/cseng/index.html), [1998](http://www.laputan.com/cgi-bin/calendar?1998)
[http://www.laputan.org](../index.html)
[![Order from Amazon.com](../images/pictures/plopd3-new.gif)](http://www.amazon.com/exec/obidos/ISBN=0201310112/7698-0074090-873253)
This volume is part of the [Addison-Wesley Software Patterns Series](http://cseng.aw.com/seriesdetail.qry?SeriesID=34).
Brian also wrote an [introduction](../plop/vigor.html) for this volume.
**[Foote & Yoder 1998b]**
[Brian Foote](mud.html#BrianFoote) and [Joseph W. Yoder](http://www.joeyoder.com/)
***[Metadata](../metadata/metadata.html)***
[Fifth Conference on Patterns Languages of Programs](http://st-www.cs.uiuc.edu/~berczuk/PLoP98/) ([PLoP '98](http://jerry.cs.uiuc.edu/~plop/plop98/final_submissions/))
Monticello, Illinois, [August 1998](http://www.laputan.com/cgi-bin/calendar?8+1998)
Technical Report #WUCS-98-25 ([PLoP '98](http://jerry.cs.uiuc.edu/~plop/plop98/final_submissions/)/[EuroPLoP '98](http://www.coldewey.com/europlop98/Program/writers.htm)), [September 1998](http://www.laputan.com/cgi-bin/calendar?9+1998)
[Department of Computer Science](http://www.cs.wustl.edu/), [Washington University](http://www.wustl.edu)
**[Fowler 1999]**
Martin Fowler
***Refactoring: Improving the Design of Existing Code***
Addison Wesley Longman, 1999
**[Gabriel 1991]**
Richard P. Gabriel
[***Lisp: Good News Bad News and How to Win Big***](../gabriel/worse-is-better.html)
[http://www.laputan.org/gabriel/worse-is-better.html](../gabriel/worse-is-better.html)
**[Gabriel 1996]**
Richard P. Gabriel
***Patterns of Software: Tales from the Software Community***
Oxford University Press, Oxford, UK, 1996
<http://www.oup-usa.org/>
**[Gamma et al. 1995]**
[Eric Gamma, Richard Helm, Ralph Johnson, and John Vlissides](../plop/gang-of-four.html)
[***Design Patterns: Elements of Reusable Object-Oriented Software***](http://st-www.cs.uiuc.edu/users/patterns/DPBook/DPBook.html)
[Addison-Wesley Longman](http://www.awl.com/cp/Gamma.html), Reading, MA, 1995
**[Garlan & Shaw 1993]**
[David Garlan](http://almond.srv.cs.cmu.edu/afs/cs.cmu.edu/user/garlan/www/home.html) and [Mary Shaw](http://spoke.compose.cs.cmu.edu/shaweb/)
***An Introduction to Software Architecture***
V. Ambriola and G. Totora, editors
*Advances in Software Engineering and Knowledge Engineering, Vol 2.*
Singapore: World Scientific Publishing, 1993, pp. 1-39
**[Ingalls 1983]**
Daniel H. H. Ingalls
***The Evolution of the Smalltalk Virtual Machine***
Smalltalk-80: Bits of History, Words of Advice
edited by Glenn Krasner
Addison-Wesley, 1983
**[Johnson & Foote 1988]**
[Ralph Johnson](http://st-www.cs.uiuc.edu/users/johnson/) and [Brian Foote](mud.html#BrianFoote)
***[Designing Reusable Classes](../drc/drc.html)***
Journal of Object-Oriented Programming
Volume 1, Number 2, June/July [1988](http://www.laputan.com/cgi-bin/calendar?1988)
**[Marick 1995]**
[Brian Marick](http://www.testing.com)
***The Craft of Software Testing***
Prentice-Hall, Upper Saddle River, NJ, 1995
**[Meszaros 1997]**
Gerard Meszaros
***Archi-Patterns: A Process Pattern Language for Defining Architectures***
Fourth Conference on Pattern Languages of Programs (PLoP '97)
Monticello, Illinois, September 1997
**[Roberts & Johnson 1998]**
[Don Roberts](http://st-www.cs.uiuc.edu/~droberts) and [Ralph E. Johnson](http://st-www.cs.uiuc.edu/users/johnson/)
[***Evolve Frameworks into Domain-Specific Languages***](http://st-www.cs.uiuc.edu/~droberts/evolve.html)
Third Conference on Patterns Languages of Programs ([PLoP '96](http://www.cs.wustl.edu/~schmidt/jointPLoP-96.html))
Monticello, Illinois, [September 1996](http://www.laputan.com/cgi-bin/calendar?9+1996)
[Technical Report #WUCS-97-07](http://www.cs.wustl.edu/~schmidt/PLoP-96/program.html), [September 1996](http://www.laputan.com/cgi-bin/calendar?9+1996)
[Department of Computer Science](http://www.cs.wustl.edu/), [Washington University](http://www.wustl.edu)
[Pattern Languages of Program Design 3](http://cseng.aw.com/bookdetail.qry?ISBN=0-201-31011-2&ptype=0)
edited by [Robert Martin](http://www.oma.com./Brochure/Resumes/rmartin.html), [Dirk Riehle](http://www.riehle.org/), and Frank Buschmann
[Addison-Wesley](http://www.awl.com/cseng/index.html), [1998](http://www.laputan.com/cgi-bin/calendar?1998)
**[Shaw 1996]**
[Mary Shaw](http://spoke.compose.cs.cmu.edu/shaweb/)
***Some Patterns for Software Architectures***
Second Conference on Patterns Languages of Programs (PLoP '95)
Monticello, Illinois, September 1995
[Pattern Languages of Program Design 2](http://cseng.aw.com/bookdetail.qry?ISBN=0-201-89527-7&ptype=0)
edited by [John M. Vlissides](http://www.software.ibm.com/qawww/despat-expert.html), [James O. Coplien](http://www.bell-labs.com/people/cope/), and Norman L. Kerth
[Addison-Wesley](http://heg-school.aw.com/cseng/index.html), [1996](http://www.laputan.com/cgi-bin/calendar?1996)
**[Simon 1969]**
Herbert A. Simon
***The Sciences of the Artificial***
MIT Press, Cambridge, MA, 1969
**[Swift 1726]**
Johnathan Swift
***[Travels Into Several Remote Nations Of The World.
In four parts. By Lemuel Gulliver, First a Surgeon, and then a Captain of several Ships.](http://www.jaffebros.com/lee/gulliver/)***
B. Motte, London, 1726.
**[Vitruvius 20 B.C.]**
Marcus Vitruvius Pollio (60 B.C-20 B.C.)
***[De Architectura](http://www.ukans.edu/history/index/europe/ancient_rome/E/Roman/Texts/Vitruvius/home.html)***
translated by Joseph Gwilt
Priestley and Weale, London, 1826
```
---
######
**Brian Foote** [foote@laputan.org](mailto:foote@laputan.org)Last Modified: *21 November 2012*
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How to destroy the Earth
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2003-04-03 by
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<h3 id='sec0'>Preamble</h3>
<p>Destroying the Earth is harder than you may have been led to believe.</p>
<p>You've seen the action movies where the bad guy threatens to destroy the Earth. You've heard people on the news claiming that the next nuclear war or cutting down rainforests or persisting in releasing hideous quantities of pollution into the atmosphere threatens to end the world.</p>
<p>Fools.</p>
<p>The Earth is built to <em>last</em>. It is a 4,550,000,000-year-old, 5,973,600,000,000,000,000,000-tonne <em>ball of iron</em>. It has taken more devastating asteroid hits in its lifetime than you've had hot dinners, and lo, it still orbits merrily. So my first piece of advice to you, dear would-be Earth-destroyer, is: do NOT think this will be easy.</p>
<p>This is not a guide for wusses whose aim is merely to wipe out humanity. I can in no way guarantee the complete extinction of the human race via any of these methods, real or imaginary. Humanity is wily and resourceful, and many of the methods outlined below will take many years to even become available, let alone implement, by which time mankind may well have spread to other planets; indeed, other star systems. If total human genocide <em>is</em> your ultimate goal, you are reading the wrong document. There are far more efficient ways of doing this, many which are available and feasible RIGHT NOW. Nor is this a guide for those wanting to annihilate everything from single-celled life upwards, render Earth uninhabitable or simply conquer it. These are <em>trivial</em> goals in comparison.</p>
<p>This is a guide for those who do not want the Earth to be there anymore.</p>
<h3>Contents</h3><ul>
<li><a href='#sec0'>Preamble</a></li>
<li><a href='#sec1'>Mission statement</a></li>
<li><a href='#sec2'>Current Earth-Destruction Status</a></li>
<li><a href='#sec3'>Methods for destroying the Earth</a></li>
<li><a href='#sec4'>Fall-back methods</a></li>
<li><a href='#sec5'>Other, less scientifically probable ways that Earth could be destroyed</a></li>
<li><a href='#sec6'>Methods from fiction</a></li>
<li><a href='#sec7'>Things which will NOT destroy the Earth</a></li>
<li><a href='#sec8'>General geocide strategy</a></li>
<li><a href='#sec9'>Credits</a></li>
</ul>
<h3 id='sec1'>Mission statement</h3>
<p>For the purposes of what I hope to be a technically and scientifically accurate document, I will define our goal thus: <b>by any means necessary, to change the Earth into something other than a planet or a dwarf planet</b>.</p>
<p>The International Astronomical Union defines a planet as:</p>
<blockquote>
<p><b>a celestial body that</b></p>
<ol>
<li><b>is in orbit around the Sun</b></li>
<li><b>has sufficient mass for its self-gravity to overcome rigid body forces so that it assumes a hydrostatic equilibrium (nearly round) shape, and</b></li>
<li><b>has cleared the neighbourhood around its orbit</b></li>
</ol>
</blockquote>
<p>and a dwarf planet as:</p>
<blockquote><p><b>a celestial body that</b></p>
<ol>
<li><b>is in orbit around the Sun</b></li>
<li><b>has sufficient mass for its self-gravity to overcome rigid body forces so that it assumes a hydrostatic equilibrium (nearly round) shape,</b></li>
<li><b>has not cleared the neighbourhood around its orbit, and</b></li>
<li><b>is not a satellite.</b></li>
</ol>
</blockquote>
<p><small>Since "celestial body" does not include the Earth, we shall assume for the sake of pedantry that the IAU meant to say "astronomical body".</small></p>
<p>These definitions instantly suggest some very simple ways of stripping the Earth of its planethood, such as hurling it into interstellar space, moving it into orbit around a gas giant, or moving it into a solar orbit whose neighbourhood is not cleared (the main asteroid belt being the most obvious choice). A slightly less obvious method would be <em>redefining "planet" not to include the Earth</em>. Naturally, these methods (the latter of which is by far the most feasible method listed in this document) will <em>not</em> be considered to count - <em>redefining something doesn't make it go away</em>.</p>
<p>We are left, therefore, with the challenge of significantly altering the Earth's physical structure, or else reducing its mass such that it can maintain a shape which is not round. For example: blowing it up, turning it into a dust cloud, merging it with a larger body, et cetera.</p>
<h3 id='sec2'>Current Earth-Destruction Status</h3>
<ul>
<li>Number of times the Earth has been destroyed: 1</li>
</ul>
<p>Information courtesy of the <a href='/board'>International Earth-Destruction Advisory Board</a></p>
<h3 id='sec3'>Methods for destroying the Earth</h3>
<p>To be listed here, a method must actually work. That is, <em>according to current scientific understanding</em>, it must be possible for the Earth to actually be destroyed by this method, however improbable or impractical it may be.</p>
<p>Methods are ranked in order of feasibility. Feasibility ratings are given out of ten - these are based primarily on my gut instinct and do not reflect actual mathematical probabilities in any way.</p>
<p>Several methods involve moving the Earth a considerable distance off its usual orbital track. This is an essay in itself, so <a href='/moving'>a separate page has been created for it</a>.</p>
<ol>
<li>
<h4>Annihilated by an equivalent quantity of antimatter</h4>
<p><b>You will need</b>: An entire planet Earth made from antimatter</p>
<p>Antimatter - the most explosive substance possible - can be manufactured in small quantities using any large particle accelerator, but this will take preposterous amounts of time to produce the required amounts. If you can create the appropriate machinery, it may be possible to find or scrape together an approximately Earth-sized chunk of rock and simply to "flip" it all through a fourth spacial dimension, turning it all to antimatter at once.</p>
<p><b>Method</b>: Once you've generated your antimatter, probably in space, just launch it en masse towards Earth. The resulting release of energy (obeying Einstein's famous mass-energy equation, E=mc<sup>2</sup>) is equivalent to the amount the Sun outputs in some <em>89 million years</em>. Alternatively, if your matter-flipping machinery is a little more flexible, turn half the Earth into antimatter (say, the Western Hemisphere) and watch the fireworks.</p>
<p><b>Earth's final resting place</b>: When matter and antimatter collide, they completely annihilate each other, leaving nothing but energy. All that would be left of Earth is a scintillating flash of light expanding across space forever. This method is one of the most permanent and total on this list, as the very matter which makes up the Earth ceases to exist, making it virtually impossible to even reassemble the planet afterwards.</p>
<p><b>Feasibility rating</b>: 2/10. It IS possible to create antimatter, so, <em>technically</em>, this method IS possible. But since the proposed matter-to-antimatter flipping machine is probably complete science fiction, we're looking at stupid, stupid amounts of time to pull this off.</p>
<p><b>Comments</b>: With a significantly smaller amount of antimatter, you can simply blow the Earth up - see later.</p>
<p><b>Source</b>: This method suggested by Thomas Wootten.</p>
</li>
<li>
<h4>Fissioned</h4>
<p><b>You will need</b>: a universal fission machine (e.g. a particle accelerator), an unimaginable amount of energy</p>
<p><b>Method</b>: Take every single atom on planet Earth and individually split each one down to become hydrogen and helium. Fissioning heavier elements to become hydrogen and helium is the opposite of the self-sustaining reaction that powers the Sun: it requires you to put energy <em>in</em> which is why the energy requirements here are so vast.</p>
<p><b>Earth's final resting place</b>: While Jupiter, Saturn, Uranus and Neptune are gas giants composed primarily of hydrogen and helium, they are massive enough to actually hold on to their tenuous atmospheres. The Earth is not; the gases would dissipate away. You'd get a wispy mess of gas where there should have been a planet.</p>
<p><b>Feasibility rating</b>: 2/10. <em>Technically</em> possible, but, again, hopelessly, mind-bogglingly inefficient and time-consuming. You're looking at billions of years <em>minimum</em>, folks.</p>
<p><b>Source</b>: This method suggested by John Routledge.</p>
</li>
<li>
<h4>Sucked into a microscopic black hole</h4>
<p><b>You will need</b>: a microscopic black hole.</p>
<p>Note that black holes are not eternal, they evaporate due to Hawking radiation. For your average black hole this takes an unimaginable amount of time, but for really small ones it could happen almost instantaneously, as evaporation time is dependent on mass. Therefore your microscopic black hole must have greater than a certain threshold mass, roughly equal to the mass of Mount Everest.</p>
<p>Creating a microscopic black hole is tricky, since one needs a reasonable amount of neutronium, but may possibly be achievable by jamming large numbers of atomic nuclei together until they stick. This is left as an exercise to the reader.</p>
<p><b>Method</b>: simply place your black hole on the surface of the Earth and wait. Black holes are of such high density that they pass through ordinary matter like a stone through the air. The black hole will plummet through the ground, eating its way to the centre of the Earth and all the way through to the other side: then, it'll oscillate back, over and over like a matter-absorbing pendulum. Eventually it will come to rest at the core, having absorbed enough matter to slow it down. Then you just need to wait, while it sits and consumes matter until the whole Earth is gone.</p>
<p><b>Earth's final resting place</b>: a singularity with a radius of <a href='http://tinyurl.com/8befk'>about nine millimetres</a>, which will then proceed to happily orbit the Sun as normal.</p>
<p><b>Feasibility rating</b>: 3/10. Highly, highly unlikely. But not impossible.</p>
<p><b>Comments</b>: Hmm. The problem is, the microscopic black hole would still be in hydrostatic equilibrium, so it would still qualify as a planet according to the IAU!</p>
<p><b>Source</b>: <a href='http://www.amazon.co.uk/exec/obidos/ASIN/0552133264/qid=1107902118/sr=1-1/ref=sr_1_2_1/026-2405488-8406058'>The Dark Side Of The Sun</a>, by Terry Pratchett. It is true that the microscopic black hole idea is an age-old science fiction mainstay which predates Pratchett by a long time, he was <em>my</em> original source for the idea, so that's what I'm putting.</p>
</li>
<li>
<h4>Cooked in a solar oven</h4>
<p><b>You will need</b>: Means for focusing a good few percent of the Sun's energy output directly on the Earth.</p>
<p>What I'm talking about here is: mirrors, and lots of them. Intercept several decent sized asteroids for raw materials and start cranking out kilometre-square sheets of lightweight reflective material (aluminised mylar, aluminium foil, nickel foil, iron foil or whatever you can scrape together). They need to be capable of changing focus direction at will because, while a few may be placed at the Earth-Sun system's Lagrangian points, the vast majority cannot be stationary in space and the relative positions of the Earth and Sun will be shifting as time passes, so attach a few manoeuvering thrusters and a communications and navigation system to each sheet.</p>
<p><a href='/data'>Preliminary calculations</a> suggest you would need roughly two trillion square kilometres of mirror.</p>
<p><b>Method</b>: Command your focusing array to concentrate as much solar energy as you can directly on the Earth - perhaps on its core, perhaps at a point on its surface. So the theory goes, this will cause the Earth to generally increase in temperature until it completely boils away, becoming a gas cloud.</p>
<p>A variation on this method involves turning the Sun into a gigantic hydrogen gas laser.</p>
<p><b>Earth's final resting place</b>: A gas cloud.</p>
<p><b>Feasibility rating</b>: 3/10. The major problem here is: What's to stop the matter cooling and becoming a planet again? In fact, once the top layer of planet becomes gaseous, what would compel it to vent into space rather than remaining on the surface, absorbing more heat and preventing the lower layers from even being heated? Unless the amount of heat put in was really immense, all you'd get is a gas planet at best, and a temporary one at that. Moving the Earth towards the Sun (see later) is likely to be a far more viable method.</p>
<p><b>Source</b>: This method suggested by Sean Timpa.</p>
</li>
<li>
<h4>Overspun</h4>
<p><b>You will need</b>: some means of accelerating the Earth's rotation.</p>
<p>Accelerating the Earth's rotation is a rather different matter from <a href='/moving'>moving it</a>. External interactions with asteroids might move the Earth but won't have a significant effect on how fast it spins. And certainly it won't spin the Earth fast enough. You need to build rockets or railguns at the Equator, all facing West. Or perhaps something more exotic...</p>
<p><b>Method</b>: The theory is, if you spin the Earth fast enough, it'll fly apart as the bits at the Equator start moving fast enough to overcome gravity. In theory, one revolution every 84 minutes should do it - even slower would be fine, in fact, as the Earth would become flatter and thus more prone to breaking apart as you spun it faster.</p>
<p><b>Feasibility rating</b>: 4/10. This could be done - there is a definite upper limit on how fast something like the Earth can spin before it breaks apart. However, spinning a planet is even more difficult than moving it. It's not as simple as attaching rockets pointing in each direction to each side...</p>
<p><b>Source</b>: This method suggested by Matthew Wakeling.</p>
</li>
<li>
<h4>Blown up</h4>
<p><b>You will need</b>: 25,000,000,000,000 tonnes of antimatter.</p>
<p><b>Method</b>: This method involves detonating a bomb so big that it blasts the Earth to pieces.</p>
<p>This, to say the least, requires a big bomb. All the explosives mankind has ever created, nuclear or non-, gathered together and detonated simultaneously, would make a significant crater and wreck the planet's ecosystem, but barely scratch the surface of the planet. There is evidence that in the past, asteroids have hit the Earth with the explosive yield of five billion Hiroshima bombs - and such evidence is <em>difficult to find</em>. It is, in short, insanely difficult to significantly alter the Earth's structure with explosives. This is not to mention the gravity problem. Just because you blasted the Earth apart doesn't mean you blasted it apart for good. If you don't blast it hard enough, the pieces will fall back together again under mutual gravitational attraction, and Earth, like the liquid metal Terminator, will reform from its shattered shards. You have to blow the Earth up hard enough to overcome that attraction.</p>
<p>How hard is that?</p>
<p>If you do the <a href='/data'>lengthy calculations</a> you find that to liberate that much energy is equivalent to the complete annihilation of around 1,246,400,000,000 tonnes of antimatter. That's assuming zero energy loss to heat, <a href='http://gltrs.grc.nasa.gov/reports/1996/TM-107030.pdf'>neutrinos</a> and radiation, which is unlikely to be the case in reality: You'll probably need to up the dose by at least a factor of twenty. Once you've generated your antimatter, probably in space, just launch it en masse towards Earth. The resulting release of energy (obeying Einstein's famous mass-energy equation, E=mc<sup>2</sup>) should be sufficient to split the Earth into a thousand pieces.</p>
<p>Greg Bear's novel, "The Forge Of God", contains an interesting refinement of this technique. Here, the antagonist instead generates antimatter in the form of a "slug" of anti-neutronium - superdense material massing a billion kilograms per cubic centimetre. This is fired into the Earth's core. Neutronium passes through ordinary matter as easily as a ball flies through the air, so the anti-neutronium slug doesn't annihilate immediately; rather, it builds up a protective sheath of plasma around it as it plunges downwards towards the Earth's core. It's then followed up by a slug of regular neutronium, which also falls into the core, at a time calculated to meet the first slug head-on at the exact centre of the Earth, where they annihilate themselves, and soon afterwards, the Earth itself. Highly space-efficient, and with the added bonus of all the energy being released at the Earth's core, where it can do the most damage. In the book, the antagonists simultaneously detonate nuclear warheads in certain oceanic trenches, to weaken the crust and allow the planet to be blown apart more easily.</p>
<p>Rearranging Earth into two planets - which, provisionally, is sufficient according to my current criteria - would take slightly less energy, but considerably more finesse.</p>
<p><b>Earth's final resting place</b>: A second asteroid belt around the Sun.</p>
<p><b>Comments</b>: trembling writes, "I still think that antimatter is crazy s**t, i.e. wouldn't want it on my flapjacks". Charles MacGee presents a very well-realised alternate source of explosives in his <a href='http://lablemminglounge.blogspot.com/2008/02/how-to-destroy-earth-isotope.html'>blog</a>; this method involves generating the explosive energy by fusing together the lighter elements of Earth's mantle (magnesium and oxygen). Of course, this would involve the invention of an efficient magnesium fusion bomb. And then turning all of the Earth's mantle into bombs. How implausible! Well. Implausibility is a relative thing.</p>
<p><a href='http://focus.aps.org/story/v23/st8'>Getting easier.</a></p>
<p><b>Feasibility rating</b>: 4/10. <em>Just about</em> slightly possible.</p>
</li>
<li>
<h4>Sucked into a giant black hole</h4>
<p><b>You will need</b>: a black hole, extremely powerful rocket engines, and, optionally, a large rocky planetary body. The nearest black hole to our planet is 1600 light years from Earth in the direction of Sagittarius, orbiting V4641.</p>
<p><b>Method</b>: after locating your black hole, you need get it and the Earth together. This is likely to be the most time-consuming part of this plan. There are two methods, moving Earth or moving the black hole, though for best results you'd most likely move both at once. See the <a href='/moving'>Guide to moving Earth</a> for details on how to move the Earth. Several of the methods listed can be applied to the black hole too, though obviously not all of them, since it is impossible to physically touch the black hole, let alone build rockets on it.</p>
<p><b>Earth's final resting place</b>: part of the mass of the black hole.</p>
<p><b>Feasibility rating</b>: 6/10. Very difficult, but <em>definitely</em> possible.</p>
<p><b>Sources</b>: The Hitch Hiker's Guide To The Galaxy, by Douglas Adams; <a href='http://www.space.com/scienceastronomy/astronomy/v4641_microquasar_000114.html'>space.com</a>.</p>
<p><b>Comments</b>: It's clear that dropping the Earth into a singularity is massive overkill. A reasonably strong gravitational field, such as might be associated with any body between Jupiter and a neutron star, would be sufficient to rip the Earth apart via tidal forces. These possibilities are dealt with further down.</p>
</li>
<li>
<h4>Meticulously and systematically deconstructed</h4>
<p><b>You will need</b>: a mass driver. A mass driver is a sort of oversized electromagnetic railgun, which was once proposed as a way of getting mined materials back from the Moon to Earth - basically, you just load it into the driver and fire it upwards in roughly the right direction. Your design should be powerful enough to hit escape velocity of 11 kilometres per second.</p>
<p>At a million tonnes of mass driven out of the Earth's gravity well per second, this would take 189,000,000 years. One mass driver would suffice, but ideally, lots (i.e. trillions) would be employed simultaneously. Alternatively you could use space elevators or conventional rockets.</p>
<p><b>Method</b>: Basically, what we're going to do here is dig up the Earth, a big chunk at a time, and boost the whole lot of it into orbit. Yes. All six sextillion tonnes of it.</p>
<p>We will ignore atmospheric considerations. Compared with the extra energy needed to overcome air friction, it would be a relatively trivial step to completely burn away the Earth's atmosphere before beginning the process. Even with this done, however, this method would require a - let me emphasize this - <em>titanic</em> quantity of energy to carry out. Building a Dyson sphere ain't gonna cut it here. (Note: Actually, it would. But if you have the technology to build a Dyson sphere, why are you reading this?)</p>
<p><b>Earth's final resting place</b>: Many tiny pieces, some dropped into the Sun, the remainder scattered across the rest of the Solar System.</p>
<p><b>Feasibility rating</b>: 6/10. If we wanted to and were willing to devote resources to it, we could start this process RIGHT NOW. Indeed, what with all the gunk left in orbit, on the Moon and heading out into space, we already have done.</p>
<p><b>Source</b>: this method arose when Joe Baldwin and I knocked our heads together by accident.</p>
<p><b>Comment</b>: Could this also be achieved with a titanic, solar-powered electromagnet?</p>
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<h4>Pulverized by impact with blunt instrument</h4>
<p><b>You will need</b>: a big heavy rock, something with a bit of a swing to it... perhaps Mars.</p>
<p><b>Method</b>: Essentially, anything can be destroyed if you hit it hard enough. ANYTHING. The concept is simple: find a really, really big asteroid or planet, accelerate it up to some dazzling speed, and smash it into Earth, preferably head-on but whatever you can manage. The result: an absolutely spectacular collision, resulting hopefully in Earth (and, most likely, our "cue ball" too) being pulverized out of existence - smashed into any number of large pieces which if the collision is hard enough should have enough energy to overcome their mutual gravity and drift away forever, never to coagulate back into a planet again.</p>
<p>A brief analysis of the size of the object required can be found <a href='http://www.madsci.org/posts/archives/jul99/931435915.As.r.html'>here</a>. Falling at the minimal impact velocity of 11 kilometres per second and assuming zero energy loss to heat and other energy forms, the cue ball would have to have roughly 60% of the mass of the Earth. Mars, the next planet out, "weighs" in at about 11% of Earth's mass, while Venus, the next planet in and also the nearest to Earth, has about 81%. Assuming that we would fire our cue ball into Earth at much greater than 11km/s (I'm thinking more like 50km/s), either of these would make great possibilities.</p>
<p>Obviously a smaller rock would do the job, you just need to fire it faster. Taking mass dilation into account, a 5,000,000,000,000-tonne asteroid at 90% of light speed would do just as well. See the <a href='/moving'>Guide to moving Earth</a> for useful information on manoeuvring big hunks of rock across interplanetary distances. For smaller chunks, there are more options - a Bussard Ramjet (scoop up interstellar hydrogen at the front and fire it out the back as propellant) is one of the most technically feasible as of right now. Of course, a run-up would be needed...</p>
<p><b>Earth's final resting place</b>: a variety of roughly Moon-sized chunks of rock, scattered haphazardly across the greater Solar System.</p>
<p><b>Feasibility rating</b>: 7/10. Pretty plausible.</p>
<p><b>Source</b>: This method suggested by Andy Kirkpatrick</p>
<p><b>Comments</b>: Earth is believed to have been hit by an object the size of Mars at some point in the distant past before its surface cooled. This titanic collision resulted in... the Moon. You can download a simulated video of the impact from <a href='http://www.swri.org/press/impact.htm'>this page</a>. While the Mars-sized object in question obviously didn't hit Earth nearly as hard as we're proposing with this method, this does serve as a proof of concept.</p>
<p>Many useful planetary facts can be found <a href='http://nssdc.gsfc.nasa.gov/planetary/planetfact.html'>here</a>.</p>
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<li>
<h4>Hurled into the Sun</h4>
<p><b>You will need</b>: <a href='/moving'>Earthmoving equipment</a>.</p>
<p><b>Method</b>: Hurl the Earth into the Sun, where it will be rapidly melted and then vaporized by the Sun's heat.</p>
<p>Sending Earth on a collision course with the Sun is not as easy as one might think. Contrary to popular opinion, Earth's orbit is not "unstable" and Earth will not begin to spiral into the Sun if we give it the slightest of nudges (otherwise, you can bet it would have happened already). It's surprisingly easy to end up with Earth in a loopy elliptical orbit which merely roasts it for four months in every eight. Careful planning will be needed to avoid this.</p>
<p>There is at least <a href='/moving'>one way</a> of moving the Sun itself. Although the Sun is much bigger, and the Earth would be carried along by its gravity, it might be possible accelerate the Sun hard enough that it eventually catches the orbiting Earth, with the same net result.</p>
<p><b>Earth's final resting place</b>: a small globule of vaporized iron sinking slowly into the heart of the Sun.</p>
<p><b>Comments</b>: As far as <a href='/data'>energy changes</a> are concerned, this method is inferior to the next one.</p>
<p>This method is essentially a variation on the Solar Oven method listed above, wherein you bring the Sun to the Earth (in a manner of speaking).</p>
<p><b>Feasibility rating</b>: 9/10. Impossible at our current technological level, but will be possible one day, I'm certain. In the meantime, may happen by freak accident if something comes out of nowhere and randomly knocks Earth in precisely the right direction.</p>
<p><b>Source</b>: <a href='http://www.amazon.com/exec/obidos/tg/detail/-/0451452011/qid=1107902396/sr=1-1/ref=sr_1_1/102-1604845-5672923?v=glance&s=books'>Infinity Welcomes Careful Drivers</a>, by Grant Naylor</p>
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<h4>Ripped apart by tidal forces</h4>
<p><b>You will need</b>: <a href='/moving'>Earthmoving equipment</a>.</p>
<p><b>Method</b>: When something (like a planet) orbits something else (like the Sun), the closer in it is, the faster it orbits. Mercury, the closest planet to the Sun, moves faster along its path than Earth, which in turn moves faster than Neptune, the furthest planet.</p>
<p>Now, if you move Earth close enough to the Sun, you'll find that it's close enough that the side of the Earth facing the Sun wants to orbit the Sun <em>faster</em> than the side pointing away from it. That causes a strain. Move Earth close enough, within an imaginary boundary called the <em>Roche Limit</em>, and the strain will be great enough to literally tear the planet Earth apart. It'll form one or more rings, much like the rings around Saturn (in fact this may be exactly where Saturn's rings came from). So our method? Move the Earth to within the Sun's Roche limit. Or, better, move it <em>out</em>, to Jupiter.</p>
<p>Moving the Earth out to Jupiter is much the same as moving the Earth in towards the Sun, the most obvious difference being your choice of vectors. However, there is another important consideration, and that is energy. It takes energy to raise or lower an object through a gravity field; it would take energy to propel the Earth into the Sun and it would take energy to propel it into Jupiter. When you <a href='/data'>do the calculations</a>, Jupiter is actually rather preferable; it takes about 38% less energy.</p>
<p>Alternatively, it may be simpler to move Jupiter to Earth. The theory works like this: build a massive free-standing tower or "candle", with its lower end deep inside Jupiter's depths and its upper end pointing into space. Put machinery inside the tower to pull hydrogen and helium gases in as fuel, through ports in the middle section, and vent these elements out through fusion thrusters at the top and bottom. The tower is called a "candle" because it burns at both ends, see? Now: the flame directed downwards into Jupiter serves to keep the tower afloat (although some secondary thrusters would be needed to also keep it stable and upright). But this lower flame has no direct effect on the Jupiter/candle system as a whole, because all the thrust from the flame is absorbed by Jupiter itself. The two objects are locked together, as if the candle is balanced on a spring or something. The <em>top</em> flame, therefore, can be used to push both the candle and Jupiter along. The top flame pushes the candle which pushes the planet. This is a little unorthodox, and it only works on gas giants, but as means for moving planets it's at least as plausible as the mass-driver and gravity-assist methods described on the <a href='/moving'>earthmoving</a> page.</p>
<p><b>Earth's final resting place</b>: lumps of heavy elements, torn apart, sinking into the massive cloud layers of Jupiter, never to be seen again.</p>
<p><b>Feasibility rating</b>: 9/10. As before, impossible at our current technological level, but will be possible one day, and in the meantime, may happen by freak accident if something comes out of nowhere and randomly knocks Earth in precisely the right direction.</p>
<p><b>Source</b>: Mitchell Porter suggested this method. Daniel T. Staal clued me in on the fusion candle technique, which he got from <a href='http://www.schlockmercenary.com/d/20030803.html'>this Shlock Mercenary comic</a>, which in turn was inspired by the novel "A World Out Of Time" by Larry Niven.</p>
</li>
</ol>
<h3 id='sec4'>Fall-back methods</h3>
<p>If your best efforts fail, you needn't fret. Nothing lasts forever; the Earth <em>is</em>, ultimately, doomed, whatever you do. The following are ways the Earth could <em>naturally</em> come to an end. (They're no longer in feasibility order since it reads better this way.) Bear in mind that none of these will require any activity on your part to be successful.</p>
<ol>
<li>
<h4>Total existence failure</h4>
<p><b>You will need</b>: nothing</p>
<p><b>Method</b>: No method. Simply sit back and twiddle your thumbs as, completely by chance, all two hundred thousand million million million million billion trillion atoms making up the planet Earth suddenly, simultaneously and spontaneously cease to exist. Note: the odds against this actually ever occuring are considerably greater than a googolplex (10<sup>10<sup>100</sup></sup>) to one. Failing this, some kind of arcane (read: scientifically laughable) probability-manipulation device may be employed.</p>
<p><b>Current feasibility rating</b>: 0/10. Even if you look at the significantly greater probability of the Earth randomly rearranging itself into separate two planets, this is utter, utter rubbish.</p>
<p><b>Source</b>: Life, The Universe And Everything, by Douglas Adams.</p>
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<h4>Written off in the backlash from a stellar collision</h4>
<p><b>You will need</b>: another star. White dwarf is good, but we're not fussy.</p>
<p><b>Method</b>: Crash your star into the Sun.</p>
<p>The interactions between the two stars in this very violent stellar event will cause more fusion to occur inside the Sun than normally does in 100,000,000 years. The result is not unlike a supernova explosion, though slower - a staggering amount of matter and energy is released outwards, burning the Earth to a crisp and firing it into interstellar space at best, completely incinerating it at worst.</p>
<p><b>Earth's final resting place</b>: burnt pieces.</p>
<p><b>Feasibility rating</b>: 4/10. This is listed under natural methods because there is absolutely no way you can move a star. Well, there are ways and means, but if you can move a star, why not <em>move the Earth into that star</em>? And the chances of this happening - even considering that in two billion years' time the Milky Way is going to collide with Andromeda - are very, very slim. Calculations suggest that the number of actual stellar <em>collisions</em> that are likely to occur in <a href='http://www.cita.utoronto.ca/~dubinski/tflops/'>that exchange</a> will be SIX. Six chances in about a hundred billion.</p>
<p>Hmm. That's actually pretty high for this list. Make it 5/10.</p>
<p><b>Source</b>: This method suggested by Eric Thompson.</p>
<p><b>Comments</b>: See the supernova entry below for more about this Andromeda collision.</p>
</li>
<li>
<h4>Swallowed up as the Sun enters red giant stage</h4>
<p><b>You will need</b>: patience</p>
<p><b>Method</b>: Simply wait for roughly 5,000,000,000 years. During its natural progress along the Main Sequence, the Sun will exhaust its initial reserves of hydrogen fuel and expand into a red giant star - swallowing up Mercury, Venus, Earth and Mars in the process.</p>
<p><b>Earth's final resting place</b>: Boiling red iron in the heart of the Sun.</p>
<p><b>Feasibility rating</b>: 8/10. It is possible that the increasing solar wind combined with the Sun's decreasing mass will result in the Earth gradually moving out to a wider, cooler, safe orbit, but <a href="https://www.nytimes.com/2008/03/11/science/space/11earth.html?_r=3">most recent work</a> suggests that this method is sound.</p>
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<li>
<h4>Crunched</h4>
<p><b>You will need</b>: considerably more patience</p>
<p><b>Method</b>: Our universe is rapidly expanding in all directions. It will likely continue to do so for a very, very long time. After that time, <em>if</em> the density of matter in the universe is greater than a certain critical value, the universe will slow to a stop due to mutual gravitational attraction, and, roughly 42,000,000,000 years from now, collapse back together again, in a reversal of the Big Bang called the <a href='http://en.wikipedia.org/wiki/Big_Crunch'>Big Crunch</a>. Conditions during the Big Crunch will be similar to those during the Big Bang: mind-boggling heat, matter ripped to subatomic particles, fundamental forces such as gravitation and electromagnetism merging back together, that sort of thing. Yes, Earth would be destroyed. So would the rest of the universe. A tiny sphere of iron stands little chance against conditions like that.</p>
<p><b>Earth's final resting place</b>: Quark-gluon plasma? Pure energy? Part of the <em>next</em> universe?</p>
<p><b>Feasibility rating</b>: 8/10. Plausible. Assumes that the Big Crunch will actually occur at all, which is currently in question.</p>
<p><b>Source</b>: Nick Snell suggested this method.</p>
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<li>
<h4>Torn a new one</h4>
<p><b>You will need</b>: about half as much patience</p>
<p><b>Method</b>: Recent experimental results seem to show that the expansion of the universe is not slowing as one might imagine it would. In fact, the expansion is accelerating. It's a bit early to say with confidence why this is happening, though phrases like "dark matter" and "phantom energy" pop up pretty frequently, but anyway, it's conjectured that if the ratio <i>w</i> of dark energy pressure to dark energy density in the universe is around -3/2 (buh?), then something of the order of 20,000,000,000 years from now, the universe would expand, accelerating in its expansion until it was ripped apart at the seams. To quote <a href='http://en.wikipedia.org/wiki/Big_Rip'>Wikipedia</a>'s entry: "First the galaxies would be separated from each other, then gravity would be too weak to hold individual galaxies together. Approximately three months before the end, solar systems will be gravitationally unbound. In the last minutes, stars and planets will come apart, and atoms will be destroyed a fraction of a second before the end of time." Cool, eh?</p>
<p><b>Earth's final resting place</b>: HAH! If I knew that, I wouldn't need aftershave.</p>
<p><b>Feasibility rating</b>: 8/10. Likely. Assumes the Big Rip theory is correct, which it probably is, but might not be.</p>
<p><b>Source</b>: a theory proposed by Robert R. Caldwell, Marc Kamionkowski, and Nevin N. Weinberg in February 2003. Read it <a href='http://arxiv.org/PS_cache/astro-ph/pdf/0302/0302506v1.pdf'>here</a> (PDF warning! Also, dense, difficult physics!). Brought to my attention by Jonah Safar and nanite.</p>
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<h4>Decayed</h4>
<p><b>You will need</b>: all-surpassing patience</p>
<p><b>Method</b>: If the Big Crunch doesn't happen, and the Big Rip doesn't happen either, then we come back to the third option: the Big Chill. For this, the universe will just expand, forever. The laws of thermodynamics take over. Every galaxy becomes isolated from its neighbours. All the stars burn out. Everything gets colder until it's all the same temperature. And after that, nothing ever changes in the universe. For eternity.</p>
<p>A lot can happen in an eternity. Protons, for example, while incredibly stable, are believed to eventually decay like any other particle. So simply wait for a period of time of the order of 1,000,000,000,000,000,000,000,000,000,000,000,000 years, and roughly half of the constituent particles of Earth will have <a href='http://en.wikipedia.org/wiki/Proton_decay'>decayed into positrons and pions</a>. If that's still too much like a planet for you, you could wait for another 10<sup>36</sup> years, leaving only a quarter of the original Earth. Or wait even longer. Eventually there will be as little of Earth left as you wish.</p>
<p><b>Earth's final resting place</b>: Miscellaneous positrons and gamma radiation (pions decay almost instantly into gamma ray photons) scattered thinly across the entire universe.</p>
<p><b>Comments</b>: It's interesting to compare this method with the one right at the top (total existence failure). What we are essentially doing here is almost exactly the same thing, only instead of expecting <em>every</em> particle to disappear at once, we are waiting patiently for a significant proportion of them to disappear, one at a time, over the course of an unimaginable period of time. Essentially we've come full circle. The scientific theories involved are the same, it's just the time scale being considered which changes the feasibility rating from "astoundingly improbable" to:</p>
<p><b>Feasibility rating</b>: 9/10. If all else fails, this one would be essentially unstoppable...</p>
<p><b>Source</b>: This method suggested by Joseph Verock.</p>
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</ol>
<p>Bobby Florea suggested to me the intriguing idea that "Evolve an Earth-destructive form of life" might count as an additional natural method for destroying the Earth. Given that we are here, and you are reading this article, it seems like this is the plan which is furthest along at the moment. Of course, this could simply be taken to be "step zero" in all the artificial methods listed above, and not an original method at all...</p>
<h3 id='sec5'>Other, less scientifically probable ways that Earth could be destroyed</h3>
<p>Here are kept the methods which sound good on paper, but might not necessarily actually work, because the science they are based on isn't necessarily valid. Read on.</p>
<ol>
<li>
<h4>Whipped by a cosmic string</h4>
<p><b>You will need</b>: a cosmic string and a whole lotta luck</p>
<p><b>Method</b>: Cosmic strings are hypothetical 1-dimensional defects in spacetime, left over from earlier phases of the universe, somewhat like cracks in ice. They are potentially universe-spanning objects, thinner than a proton but with unimaginable density - one Earth mass per 1600m of length! All you need to do is get a cosmic string near Earth, and it'll be torn apart, shredded, and sucked in. Probably the entire rest of the solar system would be too.</p>
<p><b>Earth's final resting place</b>: String.</p>
<p><b>Feasibility rating</b>: 1/10. Mind-bogglingly unlikely. Even if cosmic strings do exist, which they may not, there are probably only about ten of them left in the ENTIRE UNIVERSE. And they can't be steered, unless you have godlike powers, in which case you might as well chuck the Earth into the Sun and have done with it, so you're relying entirely on luck. This. Will. Never. Happen.</p>
<p><b>Source</b>: this method suggested by Dan Winston.</p>
</li>
<li>
<h4>Gobbled up by strangelets</h4>
<p><b>You will need</b>: Some <a href='http://www.answers.com/topic/strange-matter'>strange matter</a>.</p>
<p>Strange matter is a phase of matter which is even more dense than neutronium. It's theorized to form in particularly massive neutron stars when the pressure inside them becomes just too great for even neutronium to exist: the individual neutrons comprising the neutronium are instead broken down into strange quarks. The neutron star then becomes a "strange star" which is essentially a single gigantic nucleon.</p>
<p>Some theories suggest that a lump of strange matter ("strangelet") could remain stable outside of the intense pressure which created it. This would make it theoretically possible for strangelets of sizes all the way down to the atomic scale to exist. It's further theorized that the gravitational field of a microscopic strangelet would be enough to gobble up anything it comes in contact with, turning it into more strange matter.</p>
<p><b>Method</b>: Hijack control of a particle accelerator. I suggest the <a href='http://www.bnl.gov/RHIC/'>Relativistic Heavy Ion Collider</a> in Brookhaven National Laboratory, Long Island, New York. Use the RHIC to create a strangelet large enough to remain stable. Once created, your job is done: relax and wait as the strangelet plummets through to the Earth's core, where it will eventually swallow up the entire Earth.</p>
<p><b>Earth's final resting place</b>: a tiny glob of strange matter, perhaps a centimetre across.</p>
<p><b>Feasibility rating</b>: 3/10. Evidence for the existence of strange matter is sketchy at best; there are <a href='http://www.news.harvard.edu/gazette/2002/05.02/01-quarkstars.html'>a few neutron stars</a> which look too small to be made of neutronium, there are <a href='http://news.bbc.co.uk/1/hi/sci/tech/2502755.stm'>a few earthquakes</a> which might have been caused by a microscopic strangelet passing through the Earth at high speed, but that's about it. And even if it were possible that small stable strangelets could exist and swallow matter up in the manner described, the odds of forming one in a particle accelerator are <a href='http://www.bnl.gov/RHIC/disaster.htm'>pretty much zero</a>.</p>
</li>
<li>
<h4>The Supernova Method</h4>
<p>See: <a href='/supernova'>The Supernova Method</a></p>
</li>
<li>
<h4>Shaken to pieces</h4>
<p>See: <a href='/tesla'>Tesla's Earthquake Machine Method</a></p>
</li>
<li>
<h4>Reduced to true vacuum</h4>
<p><b>You will need</b>: An expanding bubble of true vacuum decay.</p>
<p>Some scientific theories tell us that what we may see as vacuum is only vacuum on average, and actually thriving with vast amounts of particles and antiparticles constantly appearing and then annihilating each other. However, it's postulated that at any time a small bubble of this "false vacuum" could spontaneously decay into genuinely empty "true vacuum". Usually such a bubble would contract to nothingness instantly, but under the right conditions it could expand forever, eventually destroying the entire universe.</p>
<p><b>Method</b>: There's no method here because such bubbles are quantum effects which can only really come into existence spontaneously, not by human machinations. You just have to wait for it to happen.</p>
<p><b>Earth's final resting place</b>: Unknown.</p>
<p><b>Feasibility rating</b>: 1/10. Firstly, this might be total bunk. Secondly, if it isn't total bunk, the odds against this ever happening are clearly astronomical. It's never happened at any time in the last 13.7 billion years; it seems unlikely to happen anytime soon.</p>
<p><b>Source</b>: This method suggested by Adam Mansbridge.</p>
</li>
<li>
<h4>Wormholed</h4>
<p><b>You will need</b>: A stable Einstein-Podolsky-Rosen bridge, a.k.a. a wormhole.</p>
<p><b>Method</b>: Depending on how powerful your technology is, there are a variety of possible methods. Bridging the centre of the Earth with the centre of the Sun would do the trick very efficiently, with the Sun's million-degree heat instantly boiling the Earth from the inside.</p>
<p>Alternatively, open a large wormhole at the Sun's core and the other end in deep space, rapidly venting all the Sun's fuel and hastening its transition to the Red Giant stage. Drain all this fuel rapidly enough and you might even be able to cause a supernova.</p>
<p>You could even bridge the Earth's core with deep space, causing it to implode - although the toothpaste-shaped remnant appearing at the other end may well collapse back to form a planet again.</p>
<p><b>Earth's final resting place</b>: Variable.</p>
<p><b>Feasibility rating</b>: 2/10. Wormholes probably aren't actually scientifically possible, and even if they are: opening one at the centre of the Sun? Come on.</p>
<p><b>Source</b>: This method suggested by Daniel Swartzendruber.</p>
</li>
<li>
<h4>Existence negated via time travel</h4>
<p><b>You will need</b>: a time machine, heavy rock-moving equipment/explosives.</p>
<p><b>Method</b>: Using your time machine, travel back in time just over 4,500,000,000 years to shortly (i.e. a few billenia) before the formation of the Earth. What you should find in its place is a young Sun and an accretion disc formed of the dusty/rocky material that will later become our Solar System. Find the patch of material that is likely to condense into the Earth. Now blow up, split apart and otherwise stir up the material so that it never gets a chance to come together and form the Earth. Return forwards in time in several hundred-million-year jumps, repeating the process each time so that no planet of any kind ever forms at roughly 1 AU from the Sun. If you make an error, simply go back in time and try again.</p>
<p>If your time machine is more resilient, or you don't mind dying, you could consider going further back in time. The further you go, the less you need to change the universe to prevent the Earth ever forming. Go back to a few billionths of a second after the universe began and just by being there you'll completely alter the face of the universe to come... although it was pretty hot back then...</p>
<p><b>Earth's final resting place</b>: When you finally return to the present day, you will be left with a largish asteroid belt where Earth should be. Alternatively, you may find that the matter has been assimilated into the bodies of other planets or the Sun.</p>
<p><b>Feasibility rating</b>: 1/10. This method relies on fictional technology and has no basis in real events or scientific theory. Time travel in this way is almost certainly impossible.</p>
<p><b>Comments</b>: My good friend Rob rightly informs me that this course of action does not strictly speaking "destroy" the Earth - there is no actual destruction event in which the Earth goes from existing to not existing. What one ends up with instead is a universe in which the Earth does not and never did exist.</p>
<p>Destroying Rob proved remarkably easy.</p>
</li>
<li>
<h4>Destroyed by God</h4>
<p><b>You will need</b>: God</p>
<p><b>Method</b>: Far be it from me to dictate whether God does or does not exist, but if he did, and was omnipotent, then no doubt he could destroy the Earth at a mere thought if he should decide to. Of course, the question arises of how we persuade him to do this.</p>
<p>The first idea which springs to mind is to simply bring about the Apocalypse described in the Christian Bible. Assuming the book of Revelation is an accurate, literal depiction of future events, verse 1 of chapter 21 reads "Then I saw a new heaven and a new earth, for the first heaven and the first earth had passed away, and there was no longer any sea".</p>
<p>It seems astounding that the complete destruction of an entire planet (and heaven too) would only be worth a single sentence in this lengthy account of the End Times. But on the other hand, verse 5 of the 104th Psalm reads "He [God] set the Earth on its foundations; it can never be moved", and there are other verses like this, so maybe:</p>
<ol>
<li>the New International Version of the Bible has "earth" written with a lower-case "e", which suggests that this verse could merely refer to, you know, <em>the ground</em></li>
<li>this verse could be merely metaphorical - after all, so is the creation story described in Genesis</li>
<li>it could be that the new Earth is the same as the old Earth, and "new" just means it was "wiped clean" in some sense, like an Etch-A-Sketch</li>
</ol>
<p>In all three cases, the new Earth would still need destroying for real.</p>
<p>Another suggestion, should Judaic mythology turn out to be correct, is finding and killing one or more of the <a href='http://en.wikipedia.org/wiki/Lamed_Vav_Tzadikim'><i>Lamed Vav Tzadikim</i></a>, 36 righteous men whose role in life is to justify the purpose of mankind in the eyes of God. If even one of these is missing, it is said the world would come to an end. Practically speaking, it would probably be easier to wipe out humanity than to find one of these individuals, who do not themselves know who they are.</p>
<p><b>Comments</b>: It is of course entirely possible that the means God would choose to use to destroy the Earth would be a natural, non-miraculous event such as one of those listed above.</p>
<p><b>Earth's final resting place</b>: potentially any form, anywhere.</p>
<p><b>Feasibility rating</b>: this, naturally, is entirely subjective.</p>
</li>
<li>
<p>Mike Trainor writes, "Just because we don't have the technology to destroy the planet doesn't mean no one else in the universe does. What you need to do is to point our most powerful radio-telescope transmitters at likely solar systems and taunt them. 'The girly-beings in your miserable solar system could <em>never</em> destroy a planet as cool as this one...'" Thanks, Mike. We'll get <a href='http://www.seti.org/'>SETI</a> on it.</p>
</li>
</ol>
<h3 id='sec6'>Methods from fiction</h3>
<p>This section got too big for its shell so I moved it to a <a href='/fictional'>separate page</a>.</p>
<h3 id='sec7'>Things which will NOT destroy the Earth</h3>
<ul>
<li><p>Nanotechnology. Let's be clear here: nanotechnology is nothing more than a means to an end. Programming some sort of self-replicating von Neumann machine to eat the entire Earth up has its own massive problems (like, won't the ones at the bottom be crushed into their constituent atoms?), but even if it worked - you haven't destroyed the Earth. You've just got a planet made of nanobots that still needs destroying somehow. Program them to hurl themselves into space? Well, that's Meticulous Deconstruction, above.</p></li>
<li>
<h4>Chilled</h4>
<p><b>You will need</b>: The capability to reduce the entire planet Earth to the microscopic temperatures necessary to cause it to revert to a <a href='http://en.wikipedia.org/wiki/Bose-Einstein_Condensate'>Bose-Einstein condensate</a>.</p>
<p><b>Method</b>: It's well known and reasonably well-understood that substances at extremely low temperatures can get to the point where quantum phenomena start to have macroscopic, i.e. visible, effects. For example, it can just climb right out of a container, defying gravity. As to why, you would need some quantum physics under your belt.</p>
<p>Could the same work for a whole planet? Could a sufficiently cold body (if it were shielded from the heat of the Sun and ambient background microwave radiation) just spontaneously begin to dissipate into space?</p>
<p>Another idea is to use strong magnetic fields on the condensate to cause it to display what is currently referred as an <a href='http://en.wikipedia.org/wiki/Bose-Einstein_Condensate#Unusual_characteristics'>unusual characteristic</a>, undergoing something approximating a stellar supernova on a tiny scale: imploding on itself and then exploding, with a substantial fraction of the atoms involved disappearing entirely!</p>
<p><b>Feasibility rating</b>: 4/10. The first idea may work, but the second one probably won't. This is because the experiment specifically used rubidium-85 atoms having a "negative atom-atom scattering length". I don't know what that is, but it sounds unusual for an atom, and we know for a fact that most of Earth is not made up of rubidium-85. Plus, the "disappeared" atoms didn't actually vanish, they just escaped the experiment system under high enough energy that they weren't detected escaping. And of course, generalising quantum phenomena to gigantic scales is never a great idea.</p>
</li>
<li>
<h4>Gamma Ray Burst'd</h4>
<p><b>You will need</b>: a star in Earth's stellar neighbourhood with >40 solar masses. Such massive stars are hard to come by; even Betelgeuse has only 20 solar masses. The best candidate I know of is Eta Carinae, which has over 120 solar masses but is ~7500 light years away.</p>
<p><b>Method</b>: Gamma ray bursts are powerful, short-lived floods of gamma ray photons. GRBs come in two flavours, short (less than 2 seconds) and long (2 seconds to about 3 minutes); the latter are believed to be caused by stellar explosions called hypernovae, hundreds of times more violent than ordinary supernovae. Such stars are usually billions of light years away when they explode - the fact that we can detect them at this range should tell you enough about how powerful a hypernova is. So how about triggering one locally? Any such explosion within about 20 light years would probably be violent enough to destroy the Earth itself.</p>
<p><b>Feasibility rating</b>: 0/10. This method was originally listed above, but astronomer Stephen Thorsett set me straight. It wouldn't work. Even in the titanic quantities described above, gamma rays wouldn't make a dent in Earth's actual, physical structure.</p>
<p><b>Sources</b>: Lycurgus suggested this method. Further information from <a href='http://imagine.gsfc.nasa.gov/docs/science/know_l1/bursts.html'>nasa.gov</a>.</p>
</li>
<li>
<h4>Burned away by muon-catalyzed fusion of the oceans</h4>
<p><b>You will need</b>: a supply of muons.</p>
<p><b>Method</b>: The theory runs like this. A muon is a negatively-charged particle somewhat like an electron. If you dump a load of muons into some hydrogen, then some of the muons will replace the electrons in the hydrogen atoms. Because of the mass difference, the hydrogen atoms will suddenly get much smaller, causing the hydrogen molecules to be much closer together; enough that the probability of the hydrogen nuclei just randomly fusing with each other is high.</p>
<p>So, if you instead poured your muons into the oceans, they could cause the deuterium chemically combined with the water in the oceans to spontaneously begin undergoing fusion reactions. In theory, the amount of heat/energy released by the fusion of all the water in the world would be enough to destroy it by a good few orders of magnitude.</p>
<p><b>Feasibility rating</b>: 0/10. All known muons decay in a few microseconds - fairly long for an exotic subatomic particle, but still too short to be practical, so unless you can generate your muons in bulk, for free, you don't reach energy break-even, and the fusion stops as soon as it starts instead of being self-sustaining.</p>
<p><b>Sources</b>: Muon-catalyzed fusion was theorized in the late 1940s by Andrei Sakharov, and brought to my attention by Jef Poskanzer.</p>
<p><b>Comments</b>: This method was never listed as plausible, but I put it up here anyway because the idea itself is intriguing, even if it wouldn't work.</p>
</li>
<li>
<h4>Blown up by vacuum energy detonation</h4>
<p><b>You will need</b>: some means of extracting huge amounts of energy from the vacuum.</p>
<p><b>Method</b>: Some scientific theories tell us that what we may see as vacuum is only vacuum on average, and actually thriving with vast amounts of particles and antiparticles constantly appearing and then annihilating each other. It also suggests that the volume of space enclosed by a light bulb contains enough vacuum energy to boil every ocean in the world. Therefore, vacuum energy could prove to be the most abundant energy source of any kind. Which is where you come in. All you need to do is figure out how to extract this energy and harness it in some kind of power plant - this can easily be done without arousing too much suspicion - then surreptitiously allow the reaction to run out of control. The resulting release of energy would easily be enough to annihilate all of planet Earth and probably the Sun too.</p>
<p><b>Earth's final resting place</b>: a rapidly expanding cloud of particles of varying size.</p>
<p><b>Feasibility rating</b>: 0/10. This method was originally listed as plausible, but Alan Thomas set me straight: there are about <a href='http://math.ucr.edu/home/baez/vacuum.html'>five different ways</a> to calculate the energy of the vacuum, all giving different answers. The methods which give the answers "large" or "infinite" are predicated on dodgy mathematics and almost certainly wrong.</p>
<p><b>Source</b>: <a href='http://tinyurl.com/abw9z'>3001: The Final Odyssey</a> by Arthur C. Clarke</p>
</li>
<li><p>Allowing George W. Bush to continue to exercise his will on the world. If you think this, you're completely missing the point. The power to destroy the Earth does not currently exist, and Bush's administration is not actively seeking to create such technology. Whatever Bush does, whatever the backlash from his policies on Iraq and oil and global warming, he <em>cannot</em> destroy the planet.</p></li>
<li><p>Paradoxes as described in <a href='http://imdb.com/title/tt0096874/'>Back To The Future Part II</a>. By definition, a paradox cannot actually come into existence.</p></li>
<li><p>Ceasing all thought (if the Earth is not observed, then how can it exist?). Philip K. Dick said it best: "Reality is that which, when you stop believing in it, doesn't go away."</p></li>
<li><p>Semantics. A few people suggested exploiting a loophole in my mission statement and moving the Earth into orbit around a gas giant, making it a <em>moon</em> rather than a planet, or hurling it into interstellar space where it would become a wandering interstellar object. Yeah, yeah, very clever. <em>Get back to work</em>.</p></li>
<li>
<p>Adding enough material to the planet Earth to cause it to undergo gravitational collapse and become a <em>star</em> instead of a planet. The main problem I have with this is that the Earth is made mainly from heavy, pre-fused elements. Most of it is iron which simply won't undergo fusion at all. The amount of material you'd have to add to the Earth would be massive enough to be a star in its own right, and at the end of X billion years when it stops shining you'd <em>still</em> have a core of iron remaining in orbit around the Sun!</p>
<p>Of course, someone suggested you could add still more material until it becomes a star heavy enough to go supernova, so I'm going to come clean here: I have an irrational dislike of this method. It's not going in. Sorry.</p>
</li>
<li><p>Detonating all the nuclear weapons ever created simultaneously, either all at one location or strategically placed around the globe. This will irradiate pretty much the entire globe and kill an awful lot of people, animals and plants, but will actually destroy very little of the planet itself.</p></li>
<li>
<p>Proving that 1=0.</p>
<p>If 1 did indeed equal 0, so it is reasoned, then since there is 1 Earth, there must be 0 Earths... so, if one could prove it, the Earth would cease to exist. This is specious logic. Finding a proof in mathematics does not magically change a fact from being false to being true. It merely <em>verifies rigorously</em> as true a fact that <em>always was</em> true. Thus, if 1=0 could be proved, then it would always have been true and the Earth should never have existed. But Earth is still here. QED.</p>
<p>In fact it would be impossible for there to even exist a universe in which 1 was equal to 0. For any mathematical system in which 1=0, it is extremely trivial to prove, in addition, that 1=2, 2=3, and in fact that every number is equal. Or, in other words, the mathematical system has only one number in it, 0. In a universe which obeyed such laws, there would be nothing at all.</p>
</li>
<li><p><a href='http://bioresonant.com/news.htm'>Runaway fission at the Earth's core</a>, as proposed by Tom Chalko. It is true that while the Earth is mainly iron, there are significant quantities of other trace elements present, including fissile materials like uranium, thorium and - get this - radioactive potassium which have sunk to the core where <a href='http://www.physlink.com/News/121103PotassiumCore.cfm'>latest studies</a> suggest where they are indeed undergoing fission, generating heat and keeping the interior of the Earth warm. However, if a nuclear explosion did occur at the core, it would be insulated from the surface by <em>sixty-three hundred kilometres of liquid iron</em>.</p></li>
<li><p>Gay marriage.</p></li>
</ul>
<h3 id='sec8'>General geocide strategy</h3>
<p>Destroying the Earth is not as easy as pressing a big red button. It takes decades of hard work.</p>
<ul>
<li>
<h4>Planning</h4>
<p>Without a plan, you have nothing. Sooner or later you WILL hit a snag and find yourself unable to continue: government agents will start lasering their way through your door, or you'll have your superweapon ready and armed but nowhere safe to stand when you fire it, or you'll just plain run out of money. You need to plan for as many eventualities as you can conceive of, as early as possible. When I say early, I mean early: ideally your plan should be at least 50% complete by the time you leave high school, because your career choices will be a very significant factor. You should have picked your method by this time too. (The list above isn't necessarily complete - if you come up with a better way of your own, good luck to you.) Once you have picked your method, STICK TO IT.</p>
<p>Assuming, of course, that you and whatever trusted advisors you will allow to side with you do not intend to "go down with the ship", it is particularly advisable to make plans for alternate living arrangements <em>before</em> you embark on a course of action which may result in the destruction of the Earth. Since in most cases the hypertechnology required to actually destroy the Earth is ridiculously advanced, access to an interstellar spacecraft, a space station or another habitable planet is likely to be well within your grasp, but this is not something you want to start making assumptions about.</p>
</li>
<li>
<h4>Careers</h4>
<p>At this point you need to make a very significant decision: are you going to design your doomsday machinery (all of the above methods except Total Existence Failure require a greater or lesser amount of machinery) yourself, or are you going to employ somebody else to do it for you? Unless you are an extremely gifted scientist and you really can destroy the Earth from your laboratory (which is not impossible; see the Strangelet or Von Neumann Machine methods), you're fairly likely to pick the latter.</p>
<p>If you do decide to design (and possibly build) this thing yourself, you'd be advised to pursue mainly sciences, with the main emphasis on physics (quantum, atomic, and astrophysics in particular), but also some electronic and mechanical engineering, mathematics and possibly robotics. After this, get a job working with the technology you hope to harness, build your doomsday machine in your lab, and bam, you're done.</p>
<p>If you <em>don't</em> decide to design your doomsday device yourself, and from here on, I'll assume that this is what you decided, then the plan becomes rather more complicated and your career choices will be very different. Your time in secondary and higher education would probably be best invested studying finance, economics and politics, brushing up your management, speaking and people skills, honing your powers of persuasion, and learning to exude charisma. Charisma is a big one. These skills will enable you to hopefully ascend to a position where you have access to three things:</p>
<ol>
<li><b>money</b>,</li>
<li><b>resources</b> and</li>
<li><b>manpower</b>.</li>
</ol>
<p><b>If this is a lab project</b> as described above then you'll need relatively little of all of these; enough money to run a lab, resources to keep it stocked, and manpower in the form of one or more brilliant scientists to (knowingly or otherwise) construct your doomsday device. That suggests that the best place to seek employment would be at a research institution for the areas of science you hope to employ, or maybe an organization like <a href='http://www.boeing.com/'>Boeing</a> or <a href='http://www.nasa.gov'>NASA</a>... failing that, found the organization yourself!</p>
<p><b>If this is a big, possibly space-based project</b> then you will need MUCH more to work with. You need to either work in politics or the armed forces. Politics would be an excellent choice. I say without cynicism that today, of all the people in the world, the President of the United States of America would be the person most likely to be able to destroy the Earth should he decide to. If you feel you lack the ability to make it in politics (knowledge of your weaknesses is a strength), you should join the armed forces and shoot for Supreme General or whatever the highest rank is.</p>
<p>Nancy Lebovitz suggested religion as an alternate means of gaining resources, money and manpower. Religion is undeniably a very powerful force. If you could set yourself up as a religious leader you could potentially gain a lot of supporters - who would be much more dedicated to you as a leader than a soldier would be to his general or a citizen to his King/President/Supreme Dictator-For-Life. Setting oneself up as a new prophet doesn't seem to attract much more than scepticism in this day and age, so unless you were very persuasive, you'd probably experience greatest success by hijacking an existing mainstream religion for your own ends. One potential pitfall is that there's a limit to what your followers can provide you in terms of monetary offerings and labour. Manpower alone is not enough. You'd still need at least one scientific mastermind, and frankly I see scientific masterminds as being among the least likely to follow you... But this is a kink you should be able to work out.</p>
<p>Of course, by the time it becomes even possible to destroy the Earth, Madagascar might be the dominant superpower, or the whole world might be unified as a single nation, or maybe the whole galaxy is full of humans, there's no such thing as money, and solid platinum asteroids and robot workers are plentiful. I don't know. Whatever you can manage. Anyway, once you have everything you need at your disposal, make the calls, submit your proposals, and set the project in motion.</p>
</li>
<li>
<h4>Your base</h4>
<p>At this point you will probably need to set up some sort of base of operations. It should be at a safe distance from Earth. Lurking at least one AU out of range of whatever terrible destructive force you are about to unleash is strongly recommended in most cases, but for the supernova particularly you'll want to put as much as a thousand light years between yourself and the Earth when it happens. If you <em>have</em> to be physically on Earth to begin the destruction process (e.g. hurled into Sun, antimatter blast), then <em>set a countdown</em>. Make sure the countdown timer is a) thoroughly tested and b) <em>tamper-proof</em>. The same goes for your escape route offplanet.</p>
<p>If you are currently Supreme Dictator of Earth, you could simply announce your intentions directly to your enslaved populace with relative impunity. If you can come up with some really, really good reason for destroying the Earth which people will actually agree with - for example, you want to build a far more spacious Banksian Orbital (or many of them) instead - then getting humanity on your side will prove incalculably useful. However, as a rule, you will probably want to keep the true purpose of your project secret from as many people as possible for as long as possible.</p>
<p>Some methods are much easier to cover up than others, and this should have been a major factor in your initial choice of method. If absolutely nobody apart from you knows the true purpose of your supernova-inducer until two hours after it becomes too late to turn it off, so much the better. Despite this, you should plan for (and construct your base in preparation for) your project to ultimately become public. This could occur at any time, you might have months, hours or seconds to go. This is actually the biggest potential stumbling block, and a situation you'll have to prepare for very, very carefully. Depending on how much time your opponents have to act, how powerful they are, and whether you <em>know</em> they know or not, they might make anything from a very desperate move (launching nukes at your space station regardless of the thousand innocent hostages on board) to a very subtle one (invisibly manipulating you into employing one of their undercover agents in your laboratory security forces). Your base will therefore need very strict security procedures, many layers of defence, and multiple redundancy and carefully programmed emergency overrides for every system, critical or not. You'll need weapons. And doors. Heavy doors. Assuming the worst, you personally should always be armed. If your base is in space you should permanently be wearing your space suit under your clothes. In case of betrayal, you should be able to run the entire show single-handedly from your locked-down control room, from which you should of course have an escape route.</p>
<p><em>You should always, always, always have an escape route</em>.</p>
<p>See also <a href='http://www.eviloverlord.com/lists/overlord.html'>The Evil Overlord list</a> for lots more general advice on building bases, planning escape routes, handling enemy incursions, and other tangentially related topics.</p>
</li>
<li>
<h4>Finally</h4>
<p>If the method you choose can be tried more than once (e.g. hurled into Sun, vacuum energy detonation), and your budget will stretch, you could consider practicing on smaller astronomical bodies and working your way up. For example, consider destroying Mercury, or Ceres. Don't forget to take notes on what went particularly well, what didn't work, what was unnecessary, etc., just so everything goes as smoothly as possible on the big day.</p>
<p>Take a camera. Most of the methods listed above are incredibly spectacular and witnessing them will probably be a once-in-a-lifetime opportunity for you, so remember to capture the moment.</p>
<p>And lastly, if all your efforts fail, don't give up! Remember, nobody has ever successfully destroyed the Earth.</p>
</li>
</ul>
<h3 id='sec9'>Credits</h3>
<p>This whole shebang is the original concept of, written by and copyright © qntm. Please do not copy it and post it on your website! Just take the Preamble and provide a link here. Contributions and corrections are courtesy of
"althorrat",
"ambradley",
"ariels",
Dave Babbitt,
Joe Baldwin,
Jon Burchel,
"C-Dawg",
"cakedamber",
Jon Carlson,
Matthew Cetrangelo,
"Cletus The Fetus",
"DejaMorgana",
Tobias Diedrich,
"Draknet",
Sandro Dunatov,
Dominic Eldridge,
Dave Feshy,
"Fieari",
Bobby Florea,
Matthew Fogle,
Daniel Franke,
Richard Freeman,
Aneesh Goel,
"grendelkhan",
David V. Gulliver,
Tyler Hansen,
Russell Harper,
Jordy den Hartog,
Rudy Hasspacher,
Colby Hayward,
Lars Hedbor,
"J",
Kevin A. Janka,
Wyatt Johnson,
Zachary Jones,
William Keith,
Robert Kern,
Douglas B. Killings,
Andy Kirkpatrick,
John Kniha,
Floris Kraak,
L. Kraven,
Samuel Laquedem,
Nancy Lebovitz,
Tom Ligon,
"LordFrith",
Scott Lujan,
"Lycurgus",
Gary Martin,
S. Mattison,
Robert McQueen,
Douglas Merrill,
Craig Musselman,
"nanite",
Ryan O'Connell,
Marco Pagliero,
Loren Pechtel,
Nick Peirson,
George Peterson,
Mitchell Porter,
Michael Pullmann,
Steve R,
"randombit",
Toby Richards,
Daniel W. Rickey,
"Rikmach",
John Routledge,
"Rubyflame",
Jonah Safar,
John Sahr,
Anders Sandberg,
Raj Sandhu,
James Scholes,
Mike Schulte,
"Shields",
Drake Siard,
Ian M. Slater,
Lucian Smith,
Nick Snell,
Nelson Sousa,
Jasper Spaans,
"Starrynight",
Mark Stokes,
Jasmine Strong,
Geoff Swift,
John Tackman,
"tdent",
"Thane",
M. Alan Thomas II,
Eric Thompson,
Stephen Thorsett,
Sean Timpa,
Mike Trainor,
"trick.knee",
"trembling",
Daniel A. Turner,
"Underblog",
"Ungrounded Lightning",
"unperson",
Aras Vaichas,
Joseph Verock,
Linnea W,
Matthew Wakeling,
George Waksman,
Edward Welbourne,
Henry White,
Michael Z. Williamson,
Tom Wright and
"zandrews".
</p>
<p> </p>
<h4>Next: <a href='/destro'>To destroy the Earth</a></h4> </div>
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<h3 class="page__comments-h3">Discussion (38)</h3>
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>2014-03-14 13:07:56</a>
by Vedant Mishra:
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<div class="page__comment-content">Can a planet emit energy</div>
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>2014-03-14 13:09:19</a>
by Vedant Mishra:
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<div class="page__comment-content">Please reply at itzvedanta@rediffmail.com</div>
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>2014-03-14 16:11:50</a>
by Dorobuta:
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<div class="page__comment-content">I favor the use of self replicating machines: gobble the earth up by using it to make more machines that gobble the earth up by making more machines... process is self-sustaining and accelerates.</div>
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>2014-04-03 00:17:55</a>
by Steve Maurer:
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<div class="page__comment-content">Same is missing one: sucked into a super-massive black hole. Or, more specifically, Andromeda's back hole.
You see, Andromeda is falling towards us. And while galaxies are very very fluffy, a few parts of them aren't. There is, therefore, significantly more than a non-zero chance that in approximately 4 billion years or so, the center of that much larger galaxy might be passing in our local neighborhood, and given that the black hole therein is likely to weigh at least as much as 300,000 of our suns, it could quite easily have our entire solar system into it as a light snack.
You will need: about 4 billion years. Not being already having died from the sun being a red giant. Bad luck.
Not all of us would end up inside though. Quite a bit of the earth would be converted to energy in the accretion disk, and blasted out into space as x-rays.
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>2014-04-12 18:56:36</a>
by Nothing:
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<div class="page__comment-content">You think it not easy(impossible), but for me I do not believe it.</div>
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by Nothing:
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<div class="page__comment-content">I want to destroy it to its last particle.</div>
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>2014-04-19 20:20:00</a>
by Nobody:
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<div class="page__comment-content">This blog is amazing. I learned so much from it. Now I can't decide whether to become an evil overlord or destroy the Earth!</div>
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by Butthole:
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<div class="page__comment-content">0=1, haha
That's like preventing conciousness by denying existance.
Dig a hole so big so that there is nothing but a whole hole.
keep em coming!
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>2014-06-12 17:43:28</a>
by Ketzer:
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<div class="page__comment-content">Mass driver method needs math correction: as you progress in removing mass from Earth, gravity will decrease, meaning each unit will require less energy to dispose of than the previous.</div>
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by MrBubbleSS:
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<div class="page__comment-content">I thought of another one, but it's pretty much impossible. I did the math on this myself with simple kinetic energy and ignored relativistic effects (with a little bit of looking up how much energy it takes to tear the Earth apart). If a single Hydrogen-1 particle was to strike the Earth (and transfer all energy) in the neighborhood of 1.5 sextillion times the speed of light, it would break the whole thing into pieces.</div>
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>2014-06-15 09:32:28</a>
by qntm:
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<div class="page__comment-content">What makes you think you can ignore relativistic effects?</div>
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>2014-06-26 02:26:18</a>
by Squid:
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<div class="page__comment-content">good point Sam
there are acctually lots of ways that the earth can be destroyed that he did not put. there is a rumor of a star called nemisis that orbits in a HUGE orbit around the sun and it comed=s around about every 22mil years. there have been projects that show that something has been causing a pattern like this. there are layers of irridum in the crust and carbon-14 dating shows it comes at 22 mil year intervals. supposedly nemisis manipulates the astroid belt and the oort cloud and sends astroids towards the sun. astroids have irridium in them so that is one logical way that that happens. If we could figure out how to make nemisis move faster or replicate the effects of nemisis on the astroid belts and oort clud then we could potentially destroy the world.</div>
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>2014-06-26 02:29:07</a>
by Squid:
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<div class="page__comment-content">I honsetly cant think of other ways to destroy the world but this is a very intresting topic. i hope he posts more on this.</div>
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>2014-06-26 02:45:20</a>
by Squid:
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<div class="page__comment-content">Ohh!!!!! i though of more!!!! If you have seen stargate then you know about replicators. they are those von neuman machines but they have things that move them around and they cant be destroyed (except for throwing them in the sun.)
The government could make a nova bomb (taking this idea from a mod from minecraft) that basically blows up and then it make the earth into a tiny ball that pulsates and eventually blows up scattering all the pieces all over the place. there could also be a virus that somehow used minerals in the earth to replicate and it wipes out the human race then it slowly eats away at the earth until all that is left is viruses floating in the vacuum of space, getting killed by cold and radiation from the sun. Hmm what else? or we could create a device that uses resources like dirt and stone to create more complex resources like iron and stuff. it would slowly use up the dirt and stuff and eventually it would have to start using the things it created to build more complex atoms. Wait... those would split when they started getting to be at the levels of thorium and stuff , therefore creating less complex atoms that it could use to create the more complex ones again. that basically means i created a freaking reactor of radioactive elements (a.k.a. A breeder reactor) that wont work then. this is so fun!!!! im only freaking 14 and im thinking of this! there could be a huge world war and we would have to move into space bacause we have caused the currents in the magma to litterally tear the earth apart!!!! this would be because the currents would be screwed up and they would cause the techtonic plates to move and they would slam into eachother so then the seawater would boil off touching the magma. then the magma would heat up the plates and they would melt. Then if we are lucky a astroid would comeby and hit it, therefore splattering it in a huge paintball effect through the solar syatem. you may get to mars with your cremated remains! i always wanted to go there!</div>
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>2014-06-26 03:03:04</a>
by Squid:
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<div class="page__comment-content">Do you know how a paintball explodes when it hits something? this is basically the same exact thing but on a bigger scale and with magma. acctually the magma may not splatter because the vacuum of space may pull the magma all over the place because it wants to equal out the pressure or it may have a solid shell because the cold of space (which is only 3K over absoulute zero) would solidify the magma on the outside and then it would slowly solidify on the inside. i think that the first scenario is more logical because the vacuum must be equalized.</div>
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>2014-06-26 03:03:46</a>
by Squid:
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<div class="page__comment-content">That is the paintball effect. Oh and i like Nobody's comment up some</div>
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>2014-07-07 02:51:59</a>
by DanielLC:
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<div class="page__comment-content">MrBubbleSS, using the same idea but with relativistic effects, I got a proton moving at (1-2*10^-85)c. That's barely enough energy, and I doubt it's efficient, so you'll want to add some more energy to that. If you want to double the energy, you have to divide the distance from c by four.</div>
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>2014-08-08 01:27:28</a>
by Squid:
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<div class="page__comment-content">Daniel where do you work?
thats pretty intense math
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>2014-09-16 12:03:40</a>
by flewk:
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<div class="page__comment-content">Easiest way to destroy the Earth would be move it out of orbit. Most of your methods can be changed to this for a fraction of the energy/material required. You need to move it into an unstable orbit where it will collide with another planet or sun. It can also slingshot out. Intercepting the asteroid belt will probably not be enough to destroy it and might even knock it into a stable alignment given enough time.
1. Annihilated by an equivalent quantity of antimatter
6. Blown Up
Antimatter created on Earth would have to be contained by electric/magnetic fields. As the mass increases, stability becomes an issue. Generating all of it in space could be possible one day, and then using fields to direct it towards Earth.
Even if you send this ball of antimatter at the Earth, the first wave of reactions would push the rest away and knock Earth out of its orbit.
Pretty much same thing for Blown Up. It would take a lot less explosives to push the Moon into the Earth to alter its orbit. The Moon has no atmosphere to absorb the "exhaust".
Alter orbit.
5. Overspun
8. Meticulously and systematically deconstructed
10. Hurled into the Sun
Rockets won't work. All exhaust is dumped into the atmosphere, so all it would do is heat the Earth instead of adding momentum.
By the time you have deconstructed enough of the planet, its orbit would be completely different from before. As the mass gets smaller, the successive launches would account for a larger proportion of the total momentum. Also, you would only need to dig until you reached the mantle, without the crust in place, it would be cooled and the Earth would stop spinning.
For a more economical method, add rockets or rail guns to the Moon, refer to above.
PS: It isn't the friction that causes the heat, it is the fact that air has no time to move out of the way at higher speeds. This results in compression.
9. Pulverized by impact with blunt instrument
That theory proposes an impact while Earth was still forming and cooling. That theory doesn't really make sense or is extremely unlikely for other reasons.
Anywho, the Earth and moon are both much more solid now. A collision by the moon would certainly alter the orbit of the Earth. The main problem would be trying to guess how it would effect the orbit, since you only have one Moon to try it with.
Did not read the rest.
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>2014-10-08 21:26:22</a>
by DestroyedSoul:
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<div class="page__comment-content">I would really rather have made multi billion dollar companies, and create a PMC to start my job, make the weapon of choice and then blast the shit out of this useless earth.</div>
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>2014-11-04 22:01:11</a>
by John:
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<div class="page__comment-content">So, you want to explode the Earth? Earth - E a r t h - E a r t h - E a r t h - E a r t h - E a r t h</div>
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>2014-11-28 15:25:27</a>
by BK:
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<div class="page__comment-content">Assuming the multiverse interpretation of quantum physics, there are an infinite number of versions of the Earth somewhere that are experiencing Total Existence Failure every moment. No need to wait.</div>
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>2014-12-24 22:11:16</a>
by Farmerbob1:
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<div class="page__comment-content">Put the Earth on a Diet.
Found a link here from Reddit and read over it. The Meticulous destruction and Von Neumann machine methods can be combined with orbital mechanics to create a method of destruction that would not require railgun or rocket launches.
Von Neumann machines consume the Earth, using non-equatorial regions as the source for materials. Once a significant number of machines have been built such that additional machines are difficult to supply with power, all older machines would travel to the equator as they are replaced, and begin changing the shape of the Earth from a sphere to a disk.
Once the disk is sufficiently large that materials at it's outermost surface can be pushed out of Earth orbit with little effort, opposing space elevators are built inside the disk. Two elevators would be enough. More would just let things happen faster.
Vast numbers of the Von Neumann machines would then march up the elevators carrying solids and liquids that were of little use to machine reproduction, and the elevators would push that matter into space, to eventually be collected by the Sun or other planets. The disk itself could be torn down and the component machines tossed into space. The bottom most machines are probably compressed back into near-solid metal anyway.
When the Earth has lost enough mass that it now orbits the moon, then it is no longer a planet, it's a moon.
Sure, you still have to generate all the power to make the Von Neumann machines, but you don't need massive pulses of power like railguns or rocketry. A few orbital solar mirrors to illuminate the dark side of Earth and/or increase the density of solar energy would be rather handy.
I consider this different from meticulous disassembly because it uses orbital mechanics and terraforming to create a low-power mass dispersal system.</div>
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>2014-12-27 02:25:05</a>
by Aaron Kaufman:
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<div class="page__comment-content">Regarding the black hole colliding with, oscillating through, and finally coming to rest inside the heart's core, (See e.g., David Brin's Earth), a few comments: first, as in the book, lest it is sufficiently big to start, the heart's density vs. Hawking radiative loss will cause it to dissipate harmlessly. The book got around this by making the b.h. exotic, a particularly weird singularity with reduced Hawking emissions. Secondly, and bare in mind that I didthe math only once without checking, to cconserve earth axial-spin component of angular momentum, given it's unchanging (presumably) mass as it is consumed (more on the necessity of this assumption in light of planet killing criteria later ) , the resultant angular momentum of 9mm earth remnant will render the remnant b.h. superextremal. In lay terms, it will spin too fast for it's given mass and she'd it's event horizon, likely in physical. It's alternative would be to she'd matter which can convection away the excess angular momentum. Also, though, I disagree with the comment or who suggested the eremnant would qualify as a planet. That's problematic because such a remnant would no longer have a clean neighborhood; it will be filled with the ejecta it used to she'd it's superextremal angular momentum. It would also be extremely hot and outshine the sun, constantly emittingHawking particles from just ooutside it's e.h. And would for that reason too not have cleared its neighborhood. Finally it would have other classical forces smearing it out into a ring--if we consider the singularity the remnant--or a somewhat eccentric oblate Sherwood rather than something I'd call round. This presumes it still has a fair amount of angular momentum, which is likely.</div>
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>2015-01-10 13:37:40</a>
by Martijn Krakeel:
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<div class="page__comment-content">One could "just" convince the world's population of the necessity of Earth's destruction and command every one to shovel up it's material, dirt-soil-earth you name it, put it in plenty of rockets and fire them of into space and then commit collective suicide.
Obviously you will run out of both working space and at a certain time so automation is essential. These automatons need repair bots AND need all to be set with self destructive devices to get rid of them. All this will eventually result in lack of atmosphere, gravity and the Earth's soil and therefore it's existence.
The biggest problem is convincing people this really is what needs to be done...</div>
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>2015-01-10 13:39:49</a>
by Martijn Krakeel:
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<div class="page__comment-content">About comment above:
"...working space and WORKERS at a certain time..."</div>
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>2015-01-10 22:06:27</a>
by Primal Light:
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<div class="page__comment-content">You wouldn't need to turn half of the EARTH into antimatter, just half of the CORE. Doing so would shatter the planet AND get rid of the core's gravity. By sending all the pieces far away from each other, you would reduce gravity enough that the atmosphere would not stay on ANY of the pieces, therefore exterminating all life on Earth reliant of oxygen or protection from the Sun's radiation (which is usually blocked by a combination of the atmosphere and the Earth's magnetic field... which is produced by the core).</div>
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>2015-01-30 09:12:33</a>
by the world safer anonymus:
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<div class="page__comment-content">GOOGLE GOES MAD THIS PAGE IS PROBABLY OK BUT ANYTHING OTHER WILL DESTROY THE WORLD!
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>2015-02-03 20:19:14</a>
by D. Zoom:
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<div class="page__comment-content">
Ok going to explain this out really easy in as simple terms posable.
Gravity Well Bomb (GWB) For minning.
Dont even bother reading this unless you understand advanced math.
Ok going to explain this out really easy in as simple terms as able to.
First off triangle. The strongest shape going. So a 1 foot triangle with three rods, one in each corner. On each rod 3 dumb bell shape weights hooked up to a gear on each. Made so the weight can spin around while on the rod. Maybe a foot tall for each rod. One weight near the bottom close to the triangle. One weight in the middle of the rod and one weight near the top. Maybe abec bearings to make the weights spin faster.
Top and bottom weight must spin the same way and middle weight must spin the other direction. Otherwise you have a completely different device.
Hook up gears on weights to a means to make them spin. Either a bike chain hooked up to a small engine or use other gears hooked up to a small engine. May want to use three small engines, one for each tier of spinning weights. Each tier will have three weights. So you will have a total of 9 weights spinning. Also you will want to run a current of electricity threw the rods.
In the center of the triangle raised up to the level of the middle weights put a ruby with a way to strike it with a needle very hard and fast. So the ruby fractures and makes the desired sound.
Ok Currents causes a electromagnetic field.
Weights cause a gravity well
Ruby cause the vibration inside the well.
So spinning weights explained. Getting them to spin at about the power of 1 will give you a total power of 3 in the center.
Look at it this way. if you take a pal of water and put it on its side the water falls out
But if you spin the same pal of water around faster and faster slowly bringing it up the pal will be at its side and the water will not fall out.
So basicly you are looking at you arm to the end of the bucket being the length.
Then the weight of the water.
The rpm that it takes to spin it around and keep it in the bucket.
now doing this with the weight works the same way but no water. The ends of the weights have the gravity force of 1 ok. You can't see this force but it is there.
Now with all three weight spinning you have a total of 3 on top and 3 on the bottom holding in the 3 in the middle. The top and bottom will run off up and down but will keep pressure on the one in the middle. The well in the middle will become stable.
So if you have a 1 foot well that would be from the center of the weights to the center of the triangle.
Ok so maybe you have already learned the take a 1 foot balloon into the water thing but I will explain it again. If you blow up a balloon to 1 foot in size and take it down 33 feet of water it will be 1/2 its size due to the pressure. Another 33 feet and its a 1/4 its size. so yet another will make it 1/8 its size.
So 1, 1/2 2, 1/4 3, 1/8 4, 1/16 5, 1/32 6, 1/64 7, 1/128 8, 1/246 9, 1/542 10, 1/1082 11, 1/2164 12, 1/4328 13, 1/ 8656 14, 1/17312 etc etc. you see how its builds up.
If there are 5280 feet in a mile then at 14 atm thats over 3 miles. that little 1 foot balloon would want to grow to the size of.
You are now pushing in on the center well with 3 atm like this. So that 1 foot gravity well will want to expand to 8 times its size.
The current will charge the atoms.
Striking the ruby in the center will cause a tone that it takes to fracture a lv ten stone. Different sounds different results. Very usable for mining to remove lesser stones. A level 8 stone will leave behind all level 9-10
After the stone is stuck the sound wave given of from it will shake the atoms in the given space going back and forth over and over till in the weights and rods break apart. The electric charge will demagnetize the atoms. The rods will shatter and the well will be released. Everything in a 8 foot area will be shaken apart to a single atom state in a perfect circle from the center of the triangle.
Atoms take a short time to repolarize and reform material.
Putting a faster spin on things will give larger results.
Do not use light instead of sound. Sound at least stops at space. Light dose not and burns the atoms. </div>
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>2015-02-06 20:00:48</a>
by ThinkingMan:
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<div class="page__comment-content">Wait ! Wait is the word. And this word will destroy Earth.
When the Sun is going to die, he will destroy earth and others planets very easely.
Don't need humans to do it ! Of course human will be dead looooooooonnnnngggg time before that !
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>2015-03-10 05:24:17</a>
by The One Who Bides His Time:
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<div class="page__comment-content">Whoever wrote this took to much time and effort into it. I already have the equipment for Pyra, Jake Hopper, and I (CodeNames) to rip the earth apart by quite literally jumping dimensions. I don't care what anyone thinks they know, but I have put Five years seven months and twentyeight days working on a machine base that could make more than time travel possible. Whoever reprots this will be found and sent away. If you all care about this earth, do not open the void.
From the one and only
- Rift Breaker</div>
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>2015-03-24 23:11:39</a>
by Professor Chaos:
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<div class="page__comment-content">Don't need to completely destroy it, just wipe it clean and turn it into a molten ball of magma. So long as humans are gone. And no escape route, all humans must be removed.</div>
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>2015-05-16 22:52:06</a>
by Dr. van Something:
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<div class="page__comment-content">Professor Chaos has the right of it, I think. Most people who talk in a serious vein about "destroying the world" are speaking metonymously about the destruction of all SAPIENT LIFE on Earth (and sometimes all even remotely sentient life as well, just to be sure). This remains the case regardless of whether they believe such destruction is inherently good or merited -- you may be saying "I am going to destroy the world" or "That madman's going to destroy the world", but in either case what you really mean is "destroy the human race".</div>
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>2015-05-18 10:37:38</a>
by Ofir Ben Yashar:
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<div class="page__comment-content">Haha.
Why would you destroy Earth?
It's such a beautiful place.
Besides don't you feel selfish?
You literally decide for other people to die.
Maybe they don't want to die?
You're not a god.
If they want to live their life they will live it.
If not, They will find their way to commit a suicide.
Who are you to say that earth should be destroyed.
I just don't get people.
This world is a f#cking gift, who knows maybe your next avatar will be born as a fucking cat on the street with no food.
Maybe after you die. nothing comes up a head.
So try to enjoy now the life you're living as a human. And don't even think about destroying what god gave you.
You fools.</div>
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>2015-06-02 01:23:12</a>
by Morfos:
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<div class="page__comment-content">By the definitions at the start of this article, one could destroy the earth by making it cubical...shave off bits here, dump them there, until it's no longer "generally round".</div>
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>2015-06-03 14:40:53</a>
by Scott Brooks :
</h4>
<div class="page__comment-content">I'm writing about the Hadron Collide and If the moon was strucked by it during its apogees cycle. What would be the effect?</div>
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>2015-06-03 14:57:11</a>
by Scott Brooks:
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<div class="page__comment-content">I'm sorry, as stupid as it sounds. My remodel of the remake space 1999. The moon was taken out of earth's orbit by a massive nuclear explosion. I knew nuclear methods couldn't be used but then I thought of the Hadron Collider. Since I should understand the physics of this possibility, I should try to understand it.</div>
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<a
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>2015-07-22 12:37:20</a>
by Ofir Ben Yashar:
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<div class="page__comment-content">https://www.youtube.com/watch?v=sHC7BRRrqo4</div>
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How to destroy the Earth @ Things Of Interest
[Things Of Interest](/)
[Blog](/blog)
[Geocide](/geocide)
##
How to destroy the Earth
2003-04-03 by
qntm
### Preamble
Destroying the Earth is harder than you may have been led to believe.
You've seen the action movies where the bad guy threatens to destroy the Earth. You've heard people on the news claiming that the next nuclear war or cutting down rainforests or persisting in releasing hideous quantities of pollution into the atmosphere threatens to end the world.
Fools.
The Earth is built to *last*. It is a 4,550,000,000-year-old, 5,973,600,000,000,000,000,000-tonne *ball of iron*. It has taken more devastating asteroid hits in its lifetime than you've had hot dinners, and lo, it still orbits merrily. So my first piece of advice to you, dear would-be Earth-destroyer, is: do NOT think this will be easy.
This is not a guide for wusses whose aim is merely to wipe out humanity. I can in no way guarantee the complete extinction of the human race via any of these methods, real or imaginary. Humanity is wily and resourceful, and many of the methods outlined below will take many years to even become available, let alone implement, by which time mankind may well have spread to other planets; indeed, other star systems. If total human genocide *is* your ultimate goal, you are reading the wrong document. There are far more efficient ways of doing this, many which are available and feasible RIGHT NOW. Nor is this a guide for those wanting to annihilate everything from single-celled life upwards, render Earth uninhabitable or simply conquer it. These are *trivial* goals in comparison.
This is a guide for those who do not want the Earth to be there anymore.
### Contents
* [Preamble](#sec0)
* [Mission statement](#sec1)
* [Current Earth-Destruction Status](#sec2)
* [Methods for destroying the Earth](#sec3)
* [Fall-back methods](#sec4)
* [Other, less scientifically probable ways that Earth could be destroyed](#sec5)
* [Methods from fiction](#sec6)
* [Things which will NOT destroy the Earth](#sec7)
* [General geocide strategy](#sec8)
* [Credits](#sec9)
### Mission statement
For the purposes of what I hope to be a technically and scientifically accurate document, I will define our goal thus: **by any means necessary, to change the Earth into something other than a planet or a dwarf planet**.
The International Astronomical Union defines a planet as:
>
> **a celestial body that**
>
>
> 1. **is in orbit around the Sun**
> 2. **has sufficient mass for its self-gravity to overcome rigid body forces so that it assumes a hydrostatic equilibrium (nearly round) shape, and**
> 3. **has cleared the neighbourhood around its orbit**
>
>
>
and a dwarf planet as:
> **a celestial body that**
>
>
> 1. **is in orbit around the Sun**
> 2. **has sufficient mass for its self-gravity to overcome rigid body forces so that it assumes a hydrostatic equilibrium (nearly round) shape,**
> 3. **has not cleared the neighbourhood around its orbit, and**
> 4. **is not a satellite.**
>
>
>
Since "celestial body" does not include the Earth, we shall assume for the sake of pedantry that the IAU meant to say "astronomical body".
These definitions instantly suggest some very simple ways of stripping the Earth of its planethood, such as hurling it into interstellar space, moving it into orbit around a gas giant, or moving it into a solar orbit whose neighbourhood is not cleared (the main asteroid belt being the most obvious choice). A slightly less obvious method would be *redefining "planet" not to include the Earth*. Naturally, these methods (the latter of which is by far the most feasible method listed in this document) will *not* be considered to count - *redefining something doesn't make it go away*.
We are left, therefore, with the challenge of significantly altering the Earth's physical structure, or else reducing its mass such that it can maintain a shape which is not round. For example: blowing it up, turning it into a dust cloud, merging it with a larger body, et cetera.
### Current Earth-Destruction Status
* Number of times the Earth has been destroyed: 1
Information courtesy of the [International Earth-Destruction Advisory Board](/board)
### Methods for destroying the Earth
To be listed here, a method must actually work. That is, *according to current scientific understanding*, it must be possible for the Earth to actually be destroyed by this method, however improbable or impractical it may be.
Methods are ranked in order of feasibility. Feasibility ratings are given out of ten - these are based primarily on my gut instinct and do not reflect actual mathematical probabilities in any way.
Several methods involve moving the Earth a considerable distance off its usual orbital track. This is an essay in itself, so [a separate page has been created for it](/moving).
1. #### Annihilated by an equivalent quantity of antimatter
**You will need**: An entire planet Earth made from antimatter
Antimatter - the most explosive substance possible - can be manufactured in small quantities using any large particle accelerator, but this will take preposterous amounts of time to produce the required amounts. If you can create the appropriate machinery, it may be possible to find or scrape together an approximately Earth-sized chunk of rock and simply to "flip" it all through a fourth spacial dimension, turning it all to antimatter at once.
**Method**: Once you've generated your antimatter, probably in space, just launch it en masse towards Earth. The resulting release of energy (obeying Einstein's famous mass-energy equation, E=mc2) is equivalent to the amount the Sun outputs in some *89 million years*. Alternatively, if your matter-flipping machinery is a little more flexible, turn half the Earth into antimatter (say, the Western Hemisphere) and watch the fireworks.
**Earth's final resting place**: When matter and antimatter collide, they completely annihilate each other, leaving nothing but energy. All that would be left of Earth is a scintillating flash of light expanding across space forever. This method is one of the most permanent and total on this list, as the very matter which makes up the Earth ceases to exist, making it virtually impossible to even reassemble the planet afterwards.
**Feasibility rating**: 2/10. It IS possible to create antimatter, so, *technically*, this method IS possible. But since the proposed matter-to-antimatter flipping machine is probably complete science fiction, we're looking at stupid, stupid amounts of time to pull this off.
**Comments**: With a significantly smaller amount of antimatter, you can simply blow the Earth up - see later.
**Source**: This method suggested by Thomas Wootten.
2. #### Fissioned
**You will need**: a universal fission machine (e.g. a particle accelerator), an unimaginable amount of energy
**Method**: Take every single atom on planet Earth and individually split each one down to become hydrogen and helium. Fissioning heavier elements to become hydrogen and helium is the opposite of the self-sustaining reaction that powers the Sun: it requires you to put energy *in* which is why the energy requirements here are so vast.
**Earth's final resting place**: While Jupiter, Saturn, Uranus and Neptune are gas giants composed primarily of hydrogen and helium, they are massive enough to actually hold on to their tenuous atmospheres. The Earth is not; the gases would dissipate away. You'd get a wispy mess of gas where there should have been a planet.
**Feasibility rating**: 2/10. *Technically* possible, but, again, hopelessly, mind-bogglingly inefficient and time-consuming. You're looking at billions of years *minimum*, folks.
**Source**: This method suggested by John Routledge.
3. #### Sucked into a microscopic black hole
**You will need**: a microscopic black hole.
Note that black holes are not eternal, they evaporate due to Hawking radiation. For your average black hole this takes an unimaginable amount of time, but for really small ones it could happen almost instantaneously, as evaporation time is dependent on mass. Therefore your microscopic black hole must have greater than a certain threshold mass, roughly equal to the mass of Mount Everest.
Creating a microscopic black hole is tricky, since one needs a reasonable amount of neutronium, but may possibly be achievable by jamming large numbers of atomic nuclei together until they stick. This is left as an exercise to the reader.
**Method**: simply place your black hole on the surface of the Earth and wait. Black holes are of such high density that they pass through ordinary matter like a stone through the air. The black hole will plummet through the ground, eating its way to the centre of the Earth and all the way through to the other side: then, it'll oscillate back, over and over like a matter-absorbing pendulum. Eventually it will come to rest at the core, having absorbed enough matter to slow it down. Then you just need to wait, while it sits and consumes matter until the whole Earth is gone.
**Earth's final resting place**: a singularity with a radius of [about nine millimetres](http://tinyurl.com/8befk), which will then proceed to happily orbit the Sun as normal.
**Feasibility rating**: 3/10. Highly, highly unlikely. But not impossible.
**Comments**: Hmm. The problem is, the microscopic black hole would still be in hydrostatic equilibrium, so it would still qualify as a planet according to the IAU!
**Source**: [The Dark Side Of The Sun](http://www.amazon.co.uk/exec/obidos/ASIN/0552133264/qid=1107902118/sr=1-1/ref=sr_1_2_1/026-2405488-8406058), by Terry Pratchett. It is true that the microscopic black hole idea is an age-old science fiction mainstay which predates Pratchett by a long time, he was *my* original source for the idea, so that's what I'm putting.
4. #### Cooked in a solar oven
**You will need**: Means for focusing a good few percent of the Sun's energy output directly on the Earth.
What I'm talking about here is: mirrors, and lots of them. Intercept several decent sized asteroids for raw materials and start cranking out kilometre-square sheets of lightweight reflective material (aluminised mylar, aluminium foil, nickel foil, iron foil or whatever you can scrape together). They need to be capable of changing focus direction at will because, while a few may be placed at the Earth-Sun system's Lagrangian points, the vast majority cannot be stationary in space and the relative positions of the Earth and Sun will be shifting as time passes, so attach a few manoeuvering thrusters and a communications and navigation system to each sheet.
[Preliminary calculations](/data) suggest you would need roughly two trillion square kilometres of mirror.
**Method**: Command your focusing array to concentrate as much solar energy as you can directly on the Earth - perhaps on its core, perhaps at a point on its surface. So the theory goes, this will cause the Earth to generally increase in temperature until it completely boils away, becoming a gas cloud.
A variation on this method involves turning the Sun into a gigantic hydrogen gas laser.
**Earth's final resting place**: A gas cloud.
**Feasibility rating**: 3/10. The major problem here is: What's to stop the matter cooling and becoming a planet again? In fact, once the top layer of planet becomes gaseous, what would compel it to vent into space rather than remaining on the surface, absorbing more heat and preventing the lower layers from even being heated? Unless the amount of heat put in was really immense, all you'd get is a gas planet at best, and a temporary one at that. Moving the Earth towards the Sun (see later) is likely to be a far more viable method.
**Source**: This method suggested by Sean Timpa.
5. #### Overspun
**You will need**: some means of accelerating the Earth's rotation.
Accelerating the Earth's rotation is a rather different matter from [moving it](/moving). External interactions with asteroids might move the Earth but won't have a significant effect on how fast it spins. And certainly it won't spin the Earth fast enough. You need to build rockets or railguns at the Equator, all facing West. Or perhaps something more exotic...
**Method**: The theory is, if you spin the Earth fast enough, it'll fly apart as the bits at the Equator start moving fast enough to overcome gravity. In theory, one revolution every 84 minutes should do it - even slower would be fine, in fact, as the Earth would become flatter and thus more prone to breaking apart as you spun it faster.
**Feasibility rating**: 4/10. This could be done - there is a definite upper limit on how fast something like the Earth can spin before it breaks apart. However, spinning a planet is even more difficult than moving it. It's not as simple as attaching rockets pointing in each direction to each side...
**Source**: This method suggested by Matthew Wakeling.
6. #### Blown up
**You will need**: 25,000,000,000,000 tonnes of antimatter.
**Method**: This method involves detonating a bomb so big that it blasts the Earth to pieces.
This, to say the least, requires a big bomb. All the explosives mankind has ever created, nuclear or non-, gathered together and detonated simultaneously, would make a significant crater and wreck the planet's ecosystem, but barely scratch the surface of the planet. There is evidence that in the past, asteroids have hit the Earth with the explosive yield of five billion Hiroshima bombs - and such evidence is *difficult to find*. It is, in short, insanely difficult to significantly alter the Earth's structure with explosives. This is not to mention the gravity problem. Just because you blasted the Earth apart doesn't mean you blasted it apart for good. If you don't blast it hard enough, the pieces will fall back together again under mutual gravitational attraction, and Earth, like the liquid metal Terminator, will reform from its shattered shards. You have to blow the Earth up hard enough to overcome that attraction.
How hard is that?
If you do the [lengthy calculations](/data) you find that to liberate that much energy is equivalent to the complete annihilation of around 1,246,400,000,000 tonnes of antimatter. That's assuming zero energy loss to heat, [neutrinos](http://gltrs.grc.nasa.gov/reports/1996/TM-107030.pdf) and radiation, which is unlikely to be the case in reality: You'll probably need to up the dose by at least a factor of twenty. Once you've generated your antimatter, probably in space, just launch it en masse towards Earth. The resulting release of energy (obeying Einstein's famous mass-energy equation, E=mc2) should be sufficient to split the Earth into a thousand pieces.
Greg Bear's novel, "The Forge Of God", contains an interesting refinement of this technique. Here, the antagonist instead generates antimatter in the form of a "slug" of anti-neutronium - superdense material massing a billion kilograms per cubic centimetre. This is fired into the Earth's core. Neutronium passes through ordinary matter as easily as a ball flies through the air, so the anti-neutronium slug doesn't annihilate immediately; rather, it builds up a protective sheath of plasma around it as it plunges downwards towards the Earth's core. It's then followed up by a slug of regular neutronium, which also falls into the core, at a time calculated to meet the first slug head-on at the exact centre of the Earth, where they annihilate themselves, and soon afterwards, the Earth itself. Highly space-efficient, and with the added bonus of all the energy being released at the Earth's core, where it can do the most damage. In the book, the antagonists simultaneously detonate nuclear warheads in certain oceanic trenches, to weaken the crust and allow the planet to be blown apart more easily.
Rearranging Earth into two planets - which, provisionally, is sufficient according to my current criteria - would take slightly less energy, but considerably more finesse.
**Earth's final resting place**: A second asteroid belt around the Sun.
**Comments**: trembling writes, "I still think that antimatter is crazy s\*\*t, i.e. wouldn't want it on my flapjacks". Charles MacGee presents a very well-realised alternate source of explosives in his [blog](http://lablemminglounge.blogspot.com/2008/02/how-to-destroy-earth-isotope.html); this method involves generating the explosive energy by fusing together the lighter elements of Earth's mantle (magnesium and oxygen). Of course, this would involve the invention of an efficient magnesium fusion bomb. And then turning all of the Earth's mantle into bombs. How implausible! Well. Implausibility is a relative thing.
[Getting easier.](http://focus.aps.org/story/v23/st8)
**Feasibility rating**: 4/10. *Just about* slightly possible.
7. #### Sucked into a giant black hole
**You will need**: a black hole, extremely powerful rocket engines, and, optionally, a large rocky planetary body. The nearest black hole to our planet is 1600 light years from Earth in the direction of Sagittarius, orbiting V4641.
**Method**: after locating your black hole, you need get it and the Earth together. This is likely to be the most time-consuming part of this plan. There are two methods, moving Earth or moving the black hole, though for best results you'd most likely move both at once. See the [Guide to moving Earth](/moving) for details on how to move the Earth. Several of the methods listed can be applied to the black hole too, though obviously not all of them, since it is impossible to physically touch the black hole, let alone build rockets on it.
**Earth's final resting place**: part of the mass of the black hole.
**Feasibility rating**: 6/10. Very difficult, but *definitely* possible.
**Sources**: The Hitch Hiker's Guide To The Galaxy, by Douglas Adams; [space.com](http://www.space.com/scienceastronomy/astronomy/v4641_microquasar_000114.html).
**Comments**: It's clear that dropping the Earth into a singularity is massive overkill. A reasonably strong gravitational field, such as might be associated with any body between Jupiter and a neutron star, would be sufficient to rip the Earth apart via tidal forces. These possibilities are dealt with further down.
8. #### Meticulously and systematically deconstructed
**You will need**: a mass driver. A mass driver is a sort of oversized electromagnetic railgun, which was once proposed as a way of getting mined materials back from the Moon to Earth - basically, you just load it into the driver and fire it upwards in roughly the right direction. Your design should be powerful enough to hit escape velocity of 11 kilometres per second.
At a million tonnes of mass driven out of the Earth's gravity well per second, this would take 189,000,000 years. One mass driver would suffice, but ideally, lots (i.e. trillions) would be employed simultaneously. Alternatively you could use space elevators or conventional rockets.
**Method**: Basically, what we're going to do here is dig up the Earth, a big chunk at a time, and boost the whole lot of it into orbit. Yes. All six sextillion tonnes of it.
We will ignore atmospheric considerations. Compared with the extra energy needed to overcome air friction, it would be a relatively trivial step to completely burn away the Earth's atmosphere before beginning the process. Even with this done, however, this method would require a - let me emphasize this - *titanic* quantity of energy to carry out. Building a Dyson sphere ain't gonna cut it here. (Note: Actually, it would. But if you have the technology to build a Dyson sphere, why are you reading this?)
**Earth's final resting place**: Many tiny pieces, some dropped into the Sun, the remainder scattered across the rest of the Solar System.
**Feasibility rating**: 6/10. If we wanted to and were willing to devote resources to it, we could start this process RIGHT NOW. Indeed, what with all the gunk left in orbit, on the Moon and heading out into space, we already have done.
**Source**: this method arose when Joe Baldwin and I knocked our heads together by accident.
**Comment**: Could this also be achieved with a titanic, solar-powered electromagnet?
9. #### Pulverized by impact with blunt instrument
**You will need**: a big heavy rock, something with a bit of a swing to it... perhaps Mars.
**Method**: Essentially, anything can be destroyed if you hit it hard enough. ANYTHING. The concept is simple: find a really, really big asteroid or planet, accelerate it up to some dazzling speed, and smash it into Earth, preferably head-on but whatever you can manage. The result: an absolutely spectacular collision, resulting hopefully in Earth (and, most likely, our "cue ball" too) being pulverized out of existence - smashed into any number of large pieces which if the collision is hard enough should have enough energy to overcome their mutual gravity and drift away forever, never to coagulate back into a planet again.
A brief analysis of the size of the object required can be found [here](http://www.madsci.org/posts/archives/jul99/931435915.As.r.html). Falling at the minimal impact velocity of 11 kilometres per second and assuming zero energy loss to heat and other energy forms, the cue ball would have to have roughly 60% of the mass of the Earth. Mars, the next planet out, "weighs" in at about 11% of Earth's mass, while Venus, the next planet in and also the nearest to Earth, has about 81%. Assuming that we would fire our cue ball into Earth at much greater than 11km/s (I'm thinking more like 50km/s), either of these would make great possibilities.
Obviously a smaller rock would do the job, you just need to fire it faster. Taking mass dilation into account, a 5,000,000,000,000-tonne asteroid at 90% of light speed would do just as well. See the [Guide to moving Earth](/moving) for useful information on manoeuvring big hunks of rock across interplanetary distances. For smaller chunks, there are more options - a Bussard Ramjet (scoop up interstellar hydrogen at the front and fire it out the back as propellant) is one of the most technically feasible as of right now. Of course, a run-up would be needed...
**Earth's final resting place**: a variety of roughly Moon-sized chunks of rock, scattered haphazardly across the greater Solar System.
**Feasibility rating**: 7/10. Pretty plausible.
**Source**: This method suggested by Andy Kirkpatrick
**Comments**: Earth is believed to have been hit by an object the size of Mars at some point in the distant past before its surface cooled. This titanic collision resulted in... the Moon. You can download a simulated video of the impact from [this page](http://www.swri.org/press/impact.htm). While the Mars-sized object in question obviously didn't hit Earth nearly as hard as we're proposing with this method, this does serve as a proof of concept.
Many useful planetary facts can be found [here](http://nssdc.gsfc.nasa.gov/planetary/planetfact.html).
10. #### Hurled into the Sun
**You will need**: [Earthmoving equipment](/moving).
**Method**: Hurl the Earth into the Sun, where it will be rapidly melted and then vaporized by the Sun's heat.
Sending Earth on a collision course with the Sun is not as easy as one might think. Contrary to popular opinion, Earth's orbit is not "unstable" and Earth will not begin to spiral into the Sun if we give it the slightest of nudges (otherwise, you can bet it would have happened already). It's surprisingly easy to end up with Earth in a loopy elliptical orbit which merely roasts it for four months in every eight. Careful planning will be needed to avoid this.
There is at least [one way](/moving) of moving the Sun itself. Although the Sun is much bigger, and the Earth would be carried along by its gravity, it might be possible accelerate the Sun hard enough that it eventually catches the orbiting Earth, with the same net result.
**Earth's final resting place**: a small globule of vaporized iron sinking slowly into the heart of the Sun.
**Comments**: As far as [energy changes](/data) are concerned, this method is inferior to the next one.
This method is essentially a variation on the Solar Oven method listed above, wherein you bring the Sun to the Earth (in a manner of speaking).
**Feasibility rating**: 9/10. Impossible at our current technological level, but will be possible one day, I'm certain. In the meantime, may happen by freak accident if something comes out of nowhere and randomly knocks Earth in precisely the right direction.
**Source**: [Infinity Welcomes Careful Drivers](http://www.amazon.com/exec/obidos/tg/detail/-/0451452011/qid=1107902396/sr=1-1/ref=sr_1_1/102-1604845-5672923?v=glance&s=books), by Grant Naylor
11. #### Ripped apart by tidal forces
**You will need**: [Earthmoving equipment](/moving).
**Method**: When something (like a planet) orbits something else (like the Sun), the closer in it is, the faster it orbits. Mercury, the closest planet to the Sun, moves faster along its path than Earth, which in turn moves faster than Neptune, the furthest planet.
Now, if you move Earth close enough to the Sun, you'll find that it's close enough that the side of the Earth facing the Sun wants to orbit the Sun *faster* than the side pointing away from it. That causes a strain. Move Earth close enough, within an imaginary boundary called the *Roche Limit*, and the strain will be great enough to literally tear the planet Earth apart. It'll form one or more rings, much like the rings around Saturn (in fact this may be exactly where Saturn's rings came from). So our method? Move the Earth to within the Sun's Roche limit. Or, better, move it *out*, to Jupiter.
Moving the Earth out to Jupiter is much the same as moving the Earth in towards the Sun, the most obvious difference being your choice of vectors. However, there is another important consideration, and that is energy. It takes energy to raise or lower an object through a gravity field; it would take energy to propel the Earth into the Sun and it would take energy to propel it into Jupiter. When you [do the calculations](/data), Jupiter is actually rather preferable; it takes about 38% less energy.
Alternatively, it may be simpler to move Jupiter to Earth. The theory works like this: build a massive free-standing tower or "candle", with its lower end deep inside Jupiter's depths and its upper end pointing into space. Put machinery inside the tower to pull hydrogen and helium gases in as fuel, through ports in the middle section, and vent these elements out through fusion thrusters at the top and bottom. The tower is called a "candle" because it burns at both ends, see? Now: the flame directed downwards into Jupiter serves to keep the tower afloat (although some secondary thrusters would be needed to also keep it stable and upright). But this lower flame has no direct effect on the Jupiter/candle system as a whole, because all the thrust from the flame is absorbed by Jupiter itself. The two objects are locked together, as if the candle is balanced on a spring or something. The *top* flame, therefore, can be used to push both the candle and Jupiter along. The top flame pushes the candle which pushes the planet. This is a little unorthodox, and it only works on gas giants, but as means for moving planets it's at least as plausible as the mass-driver and gravity-assist methods described on the [earthmoving](/moving) page.
**Earth's final resting place**: lumps of heavy elements, torn apart, sinking into the massive cloud layers of Jupiter, never to be seen again.
**Feasibility rating**: 9/10. As before, impossible at our current technological level, but will be possible one day, and in the meantime, may happen by freak accident if something comes out of nowhere and randomly knocks Earth in precisely the right direction.
**Source**: Mitchell Porter suggested this method. Daniel T. Staal clued me in on the fusion candle technique, which he got from [this Shlock Mercenary comic](http://www.schlockmercenary.com/d/20030803.html), which in turn was inspired by the novel "A World Out Of Time" by Larry Niven.
### Fall-back methods
If your best efforts fail, you needn't fret. Nothing lasts forever; the Earth *is*, ultimately, doomed, whatever you do. The following are ways the Earth could *naturally* come to an end. (They're no longer in feasibility order since it reads better this way.) Bear in mind that none of these will require any activity on your part to be successful.
1. #### Total existence failure
**You will need**: nothing
**Method**: No method. Simply sit back and twiddle your thumbs as, completely by chance, all two hundred thousand million million million million billion trillion atoms making up the planet Earth suddenly, simultaneously and spontaneously cease to exist. Note: the odds against this actually ever occuring are considerably greater than a googolplex (1010100) to one. Failing this, some kind of arcane (read: scientifically laughable) probability-manipulation device may be employed.
**Current feasibility rating**: 0/10. Even if you look at the significantly greater probability of the Earth randomly rearranging itself into separate two planets, this is utter, utter rubbish.
**Source**: Life, The Universe And Everything, by Douglas Adams.
2. #### Written off in the backlash from a stellar collision
**You will need**: another star. White dwarf is good, but we're not fussy.
**Method**: Crash your star into the Sun.
The interactions between the two stars in this very violent stellar event will cause more fusion to occur inside the Sun than normally does in 100,000,000 years. The result is not unlike a supernova explosion, though slower - a staggering amount of matter and energy is released outwards, burning the Earth to a crisp and firing it into interstellar space at best, completely incinerating it at worst.
**Earth's final resting place**: burnt pieces.
**Feasibility rating**: 4/10. This is listed under natural methods because there is absolutely no way you can move a star. Well, there are ways and means, but if you can move a star, why not *move the Earth into that star*? And the chances of this happening - even considering that in two billion years' time the Milky Way is going to collide with Andromeda - are very, very slim. Calculations suggest that the number of actual stellar *collisions* that are likely to occur in [that exchange](http://www.cita.utoronto.ca/~dubinski/tflops/) will be SIX. Six chances in about a hundred billion.
Hmm. That's actually pretty high for this list. Make it 5/10.
**Source**: This method suggested by Eric Thompson.
**Comments**: See the supernova entry below for more about this Andromeda collision.
3. #### Swallowed up as the Sun enters red giant stage
**You will need**: patience
**Method**: Simply wait for roughly 5,000,000,000 years. During its natural progress along the Main Sequence, the Sun will exhaust its initial reserves of hydrogen fuel and expand into a red giant star - swallowing up Mercury, Venus, Earth and Mars in the process.
**Earth's final resting place**: Boiling red iron in the heart of the Sun.
**Feasibility rating**: 8/10. It is possible that the increasing solar wind combined with the Sun's decreasing mass will result in the Earth gradually moving out to a wider, cooler, safe orbit, but [most recent work](https://www.nytimes.com/2008/03/11/science/space/11earth.html?_r=3) suggests that this method is sound.
4. #### Crunched
**You will need**: considerably more patience
**Method**: Our universe is rapidly expanding in all directions. It will likely continue to do so for a very, very long time. After that time, *if* the density of matter in the universe is greater than a certain critical value, the universe will slow to a stop due to mutual gravitational attraction, and, roughly 42,000,000,000 years from now, collapse back together again, in a reversal of the Big Bang called the [Big Crunch](http://en.wikipedia.org/wiki/Big_Crunch). Conditions during the Big Crunch will be similar to those during the Big Bang: mind-boggling heat, matter ripped to subatomic particles, fundamental forces such as gravitation and electromagnetism merging back together, that sort of thing. Yes, Earth would be destroyed. So would the rest of the universe. A tiny sphere of iron stands little chance against conditions like that.
**Earth's final resting place**: Quark-gluon plasma? Pure energy? Part of the *next* universe?
**Feasibility rating**: 8/10. Plausible. Assumes that the Big Crunch will actually occur at all, which is currently in question.
**Source**: Nick Snell suggested this method.
5. #### Torn a new one
**You will need**: about half as much patience
**Method**: Recent experimental results seem to show that the expansion of the universe is not slowing as one might imagine it would. In fact, the expansion is accelerating. It's a bit early to say with confidence why this is happening, though phrases like "dark matter" and "phantom energy" pop up pretty frequently, but anyway, it's conjectured that if the ratio *w* of dark energy pressure to dark energy density in the universe is around -3/2 (buh?), then something of the order of 20,000,000,000 years from now, the universe would expand, accelerating in its expansion until it was ripped apart at the seams. To quote [Wikipedia](http://en.wikipedia.org/wiki/Big_Rip)'s entry: "First the galaxies would be separated from each other, then gravity would be too weak to hold individual galaxies together. Approximately three months before the end, solar systems will be gravitationally unbound. In the last minutes, stars and planets will come apart, and atoms will be destroyed a fraction of a second before the end of time." Cool, eh?
**Earth's final resting place**: HAH! If I knew that, I wouldn't need aftershave.
**Feasibility rating**: 8/10. Likely. Assumes the Big Rip theory is correct, which it probably is, but might not be.
**Source**: a theory proposed by Robert R. Caldwell, Marc Kamionkowski, and Nevin N. Weinberg in February 2003. Read it [here](http://arxiv.org/PS_cache/astro-ph/pdf/0302/0302506v1.pdf) (PDF warning! Also, dense, difficult physics!). Brought to my attention by Jonah Safar and nanite.
6. #### Decayed
**You will need**: all-surpassing patience
**Method**: If the Big Crunch doesn't happen, and the Big Rip doesn't happen either, then we come back to the third option: the Big Chill. For this, the universe will just expand, forever. The laws of thermodynamics take over. Every galaxy becomes isolated from its neighbours. All the stars burn out. Everything gets colder until it's all the same temperature. And after that, nothing ever changes in the universe. For eternity.
A lot can happen in an eternity. Protons, for example, while incredibly stable, are believed to eventually decay like any other particle. So simply wait for a period of time of the order of 1,000,000,000,000,000,000,000,000,000,000,000,000 years, and roughly half of the constituent particles of Earth will have [decayed into positrons and pions](http://en.wikipedia.org/wiki/Proton_decay). If that's still too much like a planet for you, you could wait for another 1036 years, leaving only a quarter of the original Earth. Or wait even longer. Eventually there will be as little of Earth left as you wish.
**Earth's final resting place**: Miscellaneous positrons and gamma radiation (pions decay almost instantly into gamma ray photons) scattered thinly across the entire universe.
**Comments**: It's interesting to compare this method with the one right at the top (total existence failure). What we are essentially doing here is almost exactly the same thing, only instead of expecting *every* particle to disappear at once, we are waiting patiently for a significant proportion of them to disappear, one at a time, over the course of an unimaginable period of time. Essentially we've come full circle. The scientific theories involved are the same, it's just the time scale being considered which changes the feasibility rating from "astoundingly improbable" to:
**Feasibility rating**: 9/10. If all else fails, this one would be essentially unstoppable...
**Source**: This method suggested by Joseph Verock.
Bobby Florea suggested to me the intriguing idea that "Evolve an Earth-destructive form of life" might count as an additional natural method for destroying the Earth. Given that we are here, and you are reading this article, it seems like this is the plan which is furthest along at the moment. Of course, this could simply be taken to be "step zero" in all the artificial methods listed above, and not an original method at all...
### Other, less scientifically probable ways that Earth could be destroyed
Here are kept the methods which sound good on paper, but might not necessarily actually work, because the science they are based on isn't necessarily valid. Read on.
1. #### Whipped by a cosmic string
**You will need**: a cosmic string and a whole lotta luck
**Method**: Cosmic strings are hypothetical 1-dimensional defects in spacetime, left over from earlier phases of the universe, somewhat like cracks in ice. They are potentially universe-spanning objects, thinner than a proton but with unimaginable density - one Earth mass per 1600m of length! All you need to do is get a cosmic string near Earth, and it'll be torn apart, shredded, and sucked in. Probably the entire rest of the solar system would be too.
**Earth's final resting place**: String.
**Feasibility rating**: 1/10. Mind-bogglingly unlikely. Even if cosmic strings do exist, which they may not, there are probably only about ten of them left in the ENTIRE UNIVERSE. And they can't be steered, unless you have godlike powers, in which case you might as well chuck the Earth into the Sun and have done with it, so you're relying entirely on luck. This. Will. Never. Happen.
**Source**: this method suggested by Dan Winston.
2. #### Gobbled up by strangelets
**You will need**: Some [strange matter](http://www.answers.com/topic/strange-matter).
Strange matter is a phase of matter which is even more dense than neutronium. It's theorized to form in particularly massive neutron stars when the pressure inside them becomes just too great for even neutronium to exist: the individual neutrons comprising the neutronium are instead broken down into strange quarks. The neutron star then becomes a "strange star" which is essentially a single gigantic nucleon.
Some theories suggest that a lump of strange matter ("strangelet") could remain stable outside of the intense pressure which created it. This would make it theoretically possible for strangelets of sizes all the way down to the atomic scale to exist. It's further theorized that the gravitational field of a microscopic strangelet would be enough to gobble up anything it comes in contact with, turning it into more strange matter.
**Method**: Hijack control of a particle accelerator. I suggest the [Relativistic Heavy Ion Collider](http://www.bnl.gov/RHIC/) in Brookhaven National Laboratory, Long Island, New York. Use the RHIC to create a strangelet large enough to remain stable. Once created, your job is done: relax and wait as the strangelet plummets through to the Earth's core, where it will eventually swallow up the entire Earth.
**Earth's final resting place**: a tiny glob of strange matter, perhaps a centimetre across.
**Feasibility rating**: 3/10. Evidence for the existence of strange matter is sketchy at best; there are [a few neutron stars](http://www.news.harvard.edu/gazette/2002/05.02/01-quarkstars.html) which look too small to be made of neutronium, there are [a few earthquakes](http://news.bbc.co.uk/1/hi/sci/tech/2502755.stm) which might have been caused by a microscopic strangelet passing through the Earth at high speed, but that's about it. And even if it were possible that small stable strangelets could exist and swallow matter up in the manner described, the odds of forming one in a particle accelerator are [pretty much zero](http://www.bnl.gov/RHIC/disaster.htm).
3. #### The Supernova Method
See: [The Supernova Method](/supernova)
4. #### Shaken to pieces
See: [Tesla's Earthquake Machine Method](/tesla)
5. #### Reduced to true vacuum
**You will need**: An expanding bubble of true vacuum decay.
Some scientific theories tell us that what we may see as vacuum is only vacuum on average, and actually thriving with vast amounts of particles and antiparticles constantly appearing and then annihilating each other. However, it's postulated that at any time a small bubble of this "false vacuum" could spontaneously decay into genuinely empty "true vacuum". Usually such a bubble would contract to nothingness instantly, but under the right conditions it could expand forever, eventually destroying the entire universe.
**Method**: There's no method here because such bubbles are quantum effects which can only really come into existence spontaneously, not by human machinations. You just have to wait for it to happen.
**Earth's final resting place**: Unknown.
**Feasibility rating**: 1/10. Firstly, this might be total bunk. Secondly, if it isn't total bunk, the odds against this ever happening are clearly astronomical. It's never happened at any time in the last 13.7 billion years; it seems unlikely to happen anytime soon.
**Source**: This method suggested by Adam Mansbridge.
6. #### Wormholed
**You will need**: A stable Einstein-Podolsky-Rosen bridge, a.k.a. a wormhole.
**Method**: Depending on how powerful your technology is, there are a variety of possible methods. Bridging the centre of the Earth with the centre of the Sun would do the trick very efficiently, with the Sun's million-degree heat instantly boiling the Earth from the inside.
Alternatively, open a large wormhole at the Sun's core and the other end in deep space, rapidly venting all the Sun's fuel and hastening its transition to the Red Giant stage. Drain all this fuel rapidly enough and you might even be able to cause a supernova.
You could even bridge the Earth's core with deep space, causing it to implode - although the toothpaste-shaped remnant appearing at the other end may well collapse back to form a planet again.
**Earth's final resting place**: Variable.
**Feasibility rating**: 2/10. Wormholes probably aren't actually scientifically possible, and even if they are: opening one at the centre of the Sun? Come on.
**Source**: This method suggested by Daniel Swartzendruber.
7. #### Existence negated via time travel
**You will need**: a time machine, heavy rock-moving equipment/explosives.
**Method**: Using your time machine, travel back in time just over 4,500,000,000 years to shortly (i.e. a few billenia) before the formation of the Earth. What you should find in its place is a young Sun and an accretion disc formed of the dusty/rocky material that will later become our Solar System. Find the patch of material that is likely to condense into the Earth. Now blow up, split apart and otherwise stir up the material so that it never gets a chance to come together and form the Earth. Return forwards in time in several hundred-million-year jumps, repeating the process each time so that no planet of any kind ever forms at roughly 1 AU from the Sun. If you make an error, simply go back in time and try again.
If your time machine is more resilient, or you don't mind dying, you could consider going further back in time. The further you go, the less you need to change the universe to prevent the Earth ever forming. Go back to a few billionths of a second after the universe began and just by being there you'll completely alter the face of the universe to come... although it was pretty hot back then...
**Earth's final resting place**: When you finally return to the present day, you will be left with a largish asteroid belt where Earth should be. Alternatively, you may find that the matter has been assimilated into the bodies of other planets or the Sun.
**Feasibility rating**: 1/10. This method relies on fictional technology and has no basis in real events or scientific theory. Time travel in this way is almost certainly impossible.
**Comments**: My good friend Rob rightly informs me that this course of action does not strictly speaking "destroy" the Earth - there is no actual destruction event in which the Earth goes from existing to not existing. What one ends up with instead is a universe in which the Earth does not and never did exist.
Destroying Rob proved remarkably easy.
8. #### Destroyed by God
**You will need**: God
**Method**: Far be it from me to dictate whether God does or does not exist, but if he did, and was omnipotent, then no doubt he could destroy the Earth at a mere thought if he should decide to. Of course, the question arises of how we persuade him to do this.
The first idea which springs to mind is to simply bring about the Apocalypse described in the Christian Bible. Assuming the book of Revelation is an accurate, literal depiction of future events, verse 1 of chapter 21 reads "Then I saw a new heaven and a new earth, for the first heaven and the first earth had passed away, and there was no longer any sea".
It seems astounding that the complete destruction of an entire planet (and heaven too) would only be worth a single sentence in this lengthy account of the End Times. But on the other hand, verse 5 of the 104th Psalm reads "He [God] set the Earth on its foundations; it can never be moved", and there are other verses like this, so maybe:
1. the New International Version of the Bible has "earth" written with a lower-case "e", which suggests that this verse could merely refer to, you know, *the ground*
2. this verse could be merely metaphorical - after all, so is the creation story described in Genesis
3. it could be that the new Earth is the same as the old Earth, and "new" just means it was "wiped clean" in some sense, like an Etch-A-SketchIn all three cases, the new Earth would still need destroying for real.
Another suggestion, should Judaic mythology turn out to be correct, is finding and killing one or more of the [*Lamed Vav Tzadikim*](http://en.wikipedia.org/wiki/Lamed_Vav_Tzadikim), 36 righteous men whose role in life is to justify the purpose of mankind in the eyes of God. If even one of these is missing, it is said the world would come to an end. Practically speaking, it would probably be easier to wipe out humanity than to find one of these individuals, who do not themselves know who they are.
**Comments**: It is of course entirely possible that the means God would choose to use to destroy the Earth would be a natural, non-miraculous event such as one of those listed above.
**Earth's final resting place**: potentially any form, anywhere.
**Feasibility rating**: this, naturally, is entirely subjective.
9. Mike Trainor writes, "Just because we don't have the technology to destroy the planet doesn't mean no one else in the universe does. What you need to do is to point our most powerful radio-telescope transmitters at likely solar systems and taunt them. 'The girly-beings in your miserable solar system could *never* destroy a planet as cool as this one...'" Thanks, Mike. We'll get [SETI](http://www.seti.org/) on it.
### Methods from fiction
This section got too big for its shell so I moved it to a [separate page](/fictional).
### Things which will NOT destroy the Earth
* Nanotechnology. Let's be clear here: nanotechnology is nothing more than a means to an end. Programming some sort of self-replicating von Neumann machine to eat the entire Earth up has its own massive problems (like, won't the ones at the bottom be crushed into their constituent atoms?), but even if it worked - you haven't destroyed the Earth. You've just got a planet made of nanobots that still needs destroying somehow. Program them to hurl themselves into space? Well, that's Meticulous Deconstruction, above.
* #### Chilled
**You will need**: The capability to reduce the entire planet Earth to the microscopic temperatures necessary to cause it to revert to a [Bose-Einstein condensate](http://en.wikipedia.org/wiki/Bose-Einstein_Condensate).
**Method**: It's well known and reasonably well-understood that substances at extremely low temperatures can get to the point where quantum phenomena start to have macroscopic, i.e. visible, effects. For example, it can just climb right out of a container, defying gravity. As to why, you would need some quantum physics under your belt.
Could the same work for a whole planet? Could a sufficiently cold body (if it were shielded from the heat of the Sun and ambient background microwave radiation) just spontaneously begin to dissipate into space?
Another idea is to use strong magnetic fields on the condensate to cause it to display what is currently referred as an [unusual characteristic](http://en.wikipedia.org/wiki/Bose-Einstein_Condensate#Unusual_characteristics), undergoing something approximating a stellar supernova on a tiny scale: imploding on itself and then exploding, with a substantial fraction of the atoms involved disappearing entirely!
**Feasibility rating**: 4/10. The first idea may work, but the second one probably won't. This is because the experiment specifically used rubidium-85 atoms having a "negative atom-atom scattering length". I don't know what that is, but it sounds unusual for an atom, and we know for a fact that most of Earth is not made up of rubidium-85. Plus, the "disappeared" atoms didn't actually vanish, they just escaped the experiment system under high enough energy that they weren't detected escaping. And of course, generalising quantum phenomena to gigantic scales is never a great idea.
* #### Gamma Ray Burst'd
**You will need**: a star in Earth's stellar neighbourhood with >40 solar masses. Such massive stars are hard to come by; even Betelgeuse has only 20 solar masses. The best candidate I know of is Eta Carinae, which has over 120 solar masses but is ~7500 light years away.
**Method**: Gamma ray bursts are powerful, short-lived floods of gamma ray photons. GRBs come in two flavours, short (less than 2 seconds) and long (2 seconds to about 3 minutes); the latter are believed to be caused by stellar explosions called hypernovae, hundreds of times more violent than ordinary supernovae. Such stars are usually billions of light years away when they explode - the fact that we can detect them at this range should tell you enough about how powerful a hypernova is. So how about triggering one locally? Any such explosion within about 20 light years would probably be violent enough to destroy the Earth itself.
**Feasibility rating**: 0/10. This method was originally listed above, but astronomer Stephen Thorsett set me straight. It wouldn't work. Even in the titanic quantities described above, gamma rays wouldn't make a dent in Earth's actual, physical structure.
**Sources**: Lycurgus suggested this method. Further information from [nasa.gov](http://imagine.gsfc.nasa.gov/docs/science/know_l1/bursts.html).
* #### Burned away by muon-catalyzed fusion of the oceans
**You will need**: a supply of muons.
**Method**: The theory runs like this. A muon is a negatively-charged particle somewhat like an electron. If you dump a load of muons into some hydrogen, then some of the muons will replace the electrons in the hydrogen atoms. Because of the mass difference, the hydrogen atoms will suddenly get much smaller, causing the hydrogen molecules to be much closer together; enough that the probability of the hydrogen nuclei just randomly fusing with each other is high.
So, if you instead poured your muons into the oceans, they could cause the deuterium chemically combined with the water in the oceans to spontaneously begin undergoing fusion reactions. In theory, the amount of heat/energy released by the fusion of all the water in the world would be enough to destroy it by a good few orders of magnitude.
**Feasibility rating**: 0/10. All known muons decay in a few microseconds - fairly long for an exotic subatomic particle, but still too short to be practical, so unless you can generate your muons in bulk, for free, you don't reach energy break-even, and the fusion stops as soon as it starts instead of being self-sustaining.
**Sources**: Muon-catalyzed fusion was theorized in the late 1940s by Andrei Sakharov, and brought to my attention by Jef Poskanzer.
**Comments**: This method was never listed as plausible, but I put it up here anyway because the idea itself is intriguing, even if it wouldn't work.
* #### Blown up by vacuum energy detonation
**You will need**: some means of extracting huge amounts of energy from the vacuum.
**Method**: Some scientific theories tell us that what we may see as vacuum is only vacuum on average, and actually thriving with vast amounts of particles and antiparticles constantly appearing and then annihilating each other. It also suggests that the volume of space enclosed by a light bulb contains enough vacuum energy to boil every ocean in the world. Therefore, vacuum energy could prove to be the most abundant energy source of any kind. Which is where you come in. All you need to do is figure out how to extract this energy and harness it in some kind of power plant - this can easily be done without arousing too much suspicion - then surreptitiously allow the reaction to run out of control. The resulting release of energy would easily be enough to annihilate all of planet Earth and probably the Sun too.
**Earth's final resting place**: a rapidly expanding cloud of particles of varying size.
**Feasibility rating**: 0/10. This method was originally listed as plausible, but Alan Thomas set me straight: there are about [five different ways](http://math.ucr.edu/home/baez/vacuum.html) to calculate the energy of the vacuum, all giving different answers. The methods which give the answers "large" or "infinite" are predicated on dodgy mathematics and almost certainly wrong.
**Source**: [3001: The Final Odyssey](http://tinyurl.com/abw9z) by Arthur C. Clarke
* Allowing George W. Bush to continue to exercise his will on the world. If you think this, you're completely missing the point. The power to destroy the Earth does not currently exist, and Bush's administration is not actively seeking to create such technology. Whatever Bush does, whatever the backlash from his policies on Iraq and oil and global warming, he *cannot* destroy the planet.
* Paradoxes as described in [Back To The Future Part II](http://imdb.com/title/tt0096874/). By definition, a paradox cannot actually come into existence.
* Ceasing all thought (if the Earth is not observed, then how can it exist?). Philip K. Dick said it best: "Reality is that which, when you stop believing in it, doesn't go away."
* Semantics. A few people suggested exploiting a loophole in my mission statement and moving the Earth into orbit around a gas giant, making it a *moon* rather than a planet, or hurling it into interstellar space where it would become a wandering interstellar object. Yeah, yeah, very clever. *Get back to work*.
* Adding enough material to the planet Earth to cause it to undergo gravitational collapse and become a *star* instead of a planet. The main problem I have with this is that the Earth is made mainly from heavy, pre-fused elements. Most of it is iron which simply won't undergo fusion at all. The amount of material you'd have to add to the Earth would be massive enough to be a star in its own right, and at the end of X billion years when it stops shining you'd *still* have a core of iron remaining in orbit around the Sun!
Of course, someone suggested you could add still more material until it becomes a star heavy enough to go supernova, so I'm going to come clean here: I have an irrational dislike of this method. It's not going in. Sorry.
* Detonating all the nuclear weapons ever created simultaneously, either all at one location or strategically placed around the globe. This will irradiate pretty much the entire globe and kill an awful lot of people, animals and plants, but will actually destroy very little of the planet itself.
* Proving that 1=0.
If 1 did indeed equal 0, so it is reasoned, then since there is 1 Earth, there must be 0 Earths... so, if one could prove it, the Earth would cease to exist. This is specious logic. Finding a proof in mathematics does not magically change a fact from being false to being true. It merely *verifies rigorously* as true a fact that *always was* true. Thus, if 1=0 could be proved, then it would always have been true and the Earth should never have existed. But Earth is still here. QED.
In fact it would be impossible for there to even exist a universe in which 1 was equal to 0. For any mathematical system in which 1=0, it is extremely trivial to prove, in addition, that 1=2, 2=3, and in fact that every number is equal. Or, in other words, the mathematical system has only one number in it, 0. In a universe which obeyed such laws, there would be nothing at all.
* [Runaway fission at the Earth's core](http://bioresonant.com/news.htm), as proposed by Tom Chalko. It is true that while the Earth is mainly iron, there are significant quantities of other trace elements present, including fissile materials like uranium, thorium and - get this - radioactive potassium which have sunk to the core where [latest studies](http://www.physlink.com/News/121103PotassiumCore.cfm) suggest where they are indeed undergoing fission, generating heat and keeping the interior of the Earth warm. However, if a nuclear explosion did occur at the core, it would be insulated from the surface by *sixty-three hundred kilometres of liquid iron*.
* Gay marriage.
### General geocide strategy
Destroying the Earth is not as easy as pressing a big red button. It takes decades of hard work.
* #### Planning
Without a plan, you have nothing. Sooner or later you WILL hit a snag and find yourself unable to continue: government agents will start lasering their way through your door, or you'll have your superweapon ready and armed but nowhere safe to stand when you fire it, or you'll just plain run out of money. You need to plan for as many eventualities as you can conceive of, as early as possible. When I say early, I mean early: ideally your plan should be at least 50% complete by the time you leave high school, because your career choices will be a very significant factor. You should have picked your method by this time too. (The list above isn't necessarily complete - if you come up with a better way of your own, good luck to you.) Once you have picked your method, STICK TO IT.
Assuming, of course, that you and whatever trusted advisors you will allow to side with you do not intend to "go down with the ship", it is particularly advisable to make plans for alternate living arrangements *before* you embark on a course of action which may result in the destruction of the Earth. Since in most cases the hypertechnology required to actually destroy the Earth is ridiculously advanced, access to an interstellar spacecraft, a space station or another habitable planet is likely to be well within your grasp, but this is not something you want to start making assumptions about.
* #### Careers
At this point you need to make a very significant decision: are you going to design your doomsday machinery (all of the above methods except Total Existence Failure require a greater or lesser amount of machinery) yourself, or are you going to employ somebody else to do it for you? Unless you are an extremely gifted scientist and you really can destroy the Earth from your laboratory (which is not impossible; see the Strangelet or Von Neumann Machine methods), you're fairly likely to pick the latter.
If you do decide to design (and possibly build) this thing yourself, you'd be advised to pursue mainly sciences, with the main emphasis on physics (quantum, atomic, and astrophysics in particular), but also some electronic and mechanical engineering, mathematics and possibly robotics. After this, get a job working with the technology you hope to harness, build your doomsday machine in your lab, and bam, you're done.
If you *don't* decide to design your doomsday device yourself, and from here on, I'll assume that this is what you decided, then the plan becomes rather more complicated and your career choices will be very different. Your time in secondary and higher education would probably be best invested studying finance, economics and politics, brushing up your management, speaking and people skills, honing your powers of persuasion, and learning to exude charisma. Charisma is a big one. These skills will enable you to hopefully ascend to a position where you have access to three things:
1. **money**,
2. **resources** and
3. **manpower**.**If this is a lab project** as described above then you'll need relatively little of all of these; enough money to run a lab, resources to keep it stocked, and manpower in the form of one or more brilliant scientists to (knowingly or otherwise) construct your doomsday device. That suggests that the best place to seek employment would be at a research institution for the areas of science you hope to employ, or maybe an organization like [Boeing](http://www.boeing.com/) or [NASA](http://www.nasa.gov)... failing that, found the organization yourself!
**If this is a big, possibly space-based project** then you will need MUCH more to work with. You need to either work in politics or the armed forces. Politics would be an excellent choice. I say without cynicism that today, of all the people in the world, the President of the United States of America would be the person most likely to be able to destroy the Earth should he decide to. If you feel you lack the ability to make it in politics (knowledge of your weaknesses is a strength), you should join the armed forces and shoot for Supreme General or whatever the highest rank is.
Nancy Lebovitz suggested religion as an alternate means of gaining resources, money and manpower. Religion is undeniably a very powerful force. If you could set yourself up as a religious leader you could potentially gain a lot of supporters - who would be much more dedicated to you as a leader than a soldier would be to his general or a citizen to his King/President/Supreme Dictator-For-Life. Setting oneself up as a new prophet doesn't seem to attract much more than scepticism in this day and age, so unless you were very persuasive, you'd probably experience greatest success by hijacking an existing mainstream religion for your own ends. One potential pitfall is that there's a limit to what your followers can provide you in terms of monetary offerings and labour. Manpower alone is not enough. You'd still need at least one scientific mastermind, and frankly I see scientific masterminds as being among the least likely to follow you... But this is a kink you should be able to work out.
Of course, by the time it becomes even possible to destroy the Earth, Madagascar might be the dominant superpower, or the whole world might be unified as a single nation, or maybe the whole galaxy is full of humans, there's no such thing as money, and solid platinum asteroids and robot workers are plentiful. I don't know. Whatever you can manage. Anyway, once you have everything you need at your disposal, make the calls, submit your proposals, and set the project in motion.
* #### Your base
At this point you will probably need to set up some sort of base of operations. It should be at a safe distance from Earth. Lurking at least one AU out of range of whatever terrible destructive force you are about to unleash is strongly recommended in most cases, but for the supernova particularly you'll want to put as much as a thousand light years between yourself and the Earth when it happens. If you *have* to be physically on Earth to begin the destruction process (e.g. hurled into Sun, antimatter blast), then *set a countdown*. Make sure the countdown timer is a) thoroughly tested and b) *tamper-proof*. The same goes for your escape route offplanet.
If you are currently Supreme Dictator of Earth, you could simply announce your intentions directly to your enslaved populace with relative impunity. If you can come up with some really, really good reason for destroying the Earth which people will actually agree with - for example, you want to build a far more spacious Banksian Orbital (or many of them) instead - then getting humanity on your side will prove incalculably useful. However, as a rule, you will probably want to keep the true purpose of your project secret from as many people as possible for as long as possible.
Some methods are much easier to cover up than others, and this should have been a major factor in your initial choice of method. If absolutely nobody apart from you knows the true purpose of your supernova-inducer until two hours after it becomes too late to turn it off, so much the better. Despite this, you should plan for (and construct your base in preparation for) your project to ultimately become public. This could occur at any time, you might have months, hours or seconds to go. This is actually the biggest potential stumbling block, and a situation you'll have to prepare for very, very carefully. Depending on how much time your opponents have to act, how powerful they are, and whether you *know* they know or not, they might make anything from a very desperate move (launching nukes at your space station regardless of the thousand innocent hostages on board) to a very subtle one (invisibly manipulating you into employing one of their undercover agents in your laboratory security forces). Your base will therefore need very strict security procedures, many layers of defence, and multiple redundancy and carefully programmed emergency overrides for every system, critical or not. You'll need weapons. And doors. Heavy doors. Assuming the worst, you personally should always be armed. If your base is in space you should permanently be wearing your space suit under your clothes. In case of betrayal, you should be able to run the entire show single-handedly from your locked-down control room, from which you should of course have an escape route.
*You should always, always, always have an escape route*.
See also [The Evil Overlord list](http://www.eviloverlord.com/lists/overlord.html) for lots more general advice on building bases, planning escape routes, handling enemy incursions, and other tangentially related topics.
* #### Finally
If the method you choose can be tried more than once (e.g. hurled into Sun, vacuum energy detonation), and your budget will stretch, you could consider practicing on smaller astronomical bodies and working your way up. For example, consider destroying Mercury, or Ceres. Don't forget to take notes on what went particularly well, what didn't work, what was unnecessary, etc., just so everything goes as smoothly as possible on the big day.
Take a camera. Most of the methods listed above are incredibly spectacular and witnessing them will probably be a once-in-a-lifetime opportunity for you, so remember to capture the moment.
And lastly, if all your efforts fail, don't give up! Remember, nobody has ever successfully destroyed the Earth.
### Credits
This whole shebang is the original concept of, written by and copyright © qntm. Please do not copy it and post it on your website! Just take the Preamble and provide a link here. Contributions and corrections are courtesy of
"althorrat",
"ambradley",
"ariels",
Dave Babbitt,
Joe Baldwin,
Jon Burchel,
"C-Dawg",
"cakedamber",
Jon Carlson,
Matthew Cetrangelo,
"Cletus The Fetus",
"DejaMorgana",
Tobias Diedrich,
"Draknet",
Sandro Dunatov,
Dominic Eldridge,
Dave Feshy,
"Fieari",
Bobby Florea,
Matthew Fogle,
Daniel Franke,
Richard Freeman,
Aneesh Goel,
"grendelkhan",
David V. Gulliver,
Tyler Hansen,
Russell Harper,
Jordy den Hartog,
Rudy Hasspacher,
Colby Hayward,
Lars Hedbor,
"J",
Kevin A. Janka,
Wyatt Johnson,
Zachary Jones,
William Keith,
Robert Kern,
Douglas B. Killings,
Andy Kirkpatrick,
John Kniha,
Floris Kraak,
L. Kraven,
Samuel Laquedem,
Nancy Lebovitz,
Tom Ligon,
"LordFrith",
Scott Lujan,
"Lycurgus",
Gary Martin,
S. Mattison,
Robert McQueen,
Douglas Merrill,
Craig Musselman,
"nanite",
Ryan O'Connell,
Marco Pagliero,
Loren Pechtel,
Nick Peirson,
George Peterson,
Mitchell Porter,
Michael Pullmann,
Steve R,
"randombit",
Toby Richards,
Daniel W. Rickey,
"Rikmach",
John Routledge,
"Rubyflame",
Jonah Safar,
John Sahr,
Anders Sandberg,
Raj Sandhu,
James Scholes,
Mike Schulte,
"Shields",
Drake Siard,
Ian M. Slater,
Lucian Smith,
Nick Snell,
Nelson Sousa,
Jasper Spaans,
"Starrynight",
Mark Stokes,
Jasmine Strong,
Geoff Swift,
John Tackman,
"tdent",
"Thane",
M. Alan Thomas II,
Eric Thompson,
Stephen Thorsett,
Sean Timpa,
Mike Trainor,
"trick.knee",
"trembling",
Daniel A. Turner,
"Underblog",
"Ungrounded Lightning",
"unperson",
Aras Vaichas,
Joseph Verock,
Linnea W,
Matthew Wakeling,
George Waksman,
Edward Welbourne,
Henry White,
Michael Z. Williamson,
Tom Wright and
"zandrews".
#### Next: [To destroy the Earth](/destro)
[Back to Geocide](/geocide)
[Back to Blog](/blog)
[Back to Things Of Interest](/)
Show discussion (38)
### Discussion (38)
####
[2014-03-14 13:07:56](#komment5322ff2cc2e14)
by Vedant Mishra:
Can a planet emit energy
####
[2014-03-14 13:09:19](#komment5322ff7f615c3)
by Vedant Mishra:
Please reply at itzvedanta@rediffmail.com
####
[2014-03-14 16:11:50](#komment53232a46de305)
by Dorobuta:
I favor the use of self replicating machines: gobble the earth up by using it to make more machines that gobble the earth up by making more machines... process is self-sustaining and accelerates.
####
[2014-04-03 00:17:55](#komment533c9aa30cdc0)
by Steve Maurer:
Same is missing one: sucked into a super-massive black hole. Or, more specifically, Andromeda's back hole.
You see, Andromeda is falling towards us. And while galaxies are very very fluffy, a few parts of them aren't. There is, therefore, significantly more than a non-zero chance that in approximately 4 billion years or so, the center of that much larger galaxy might be passing in our local neighborhood, and given that the black hole therein is likely to weigh at least as much as 300,000 of our suns, it could quite easily have our entire solar system into it as a light snack.
You will need: about 4 billion years. Not being already having died from the sun being a red giant. Bad luck.
Not all of us would end up inside though. Quite a bit of the earth would be converted to energy in the accretion disk, and blasted out into space as x-rays.
####
[2014-04-12 18:56:36](#komment53497e5455837)
by Nothing:
You think it not easy(impossible), but for me I do not believe it.
####
[2014-04-12 19:10:41](#komment534981a12b1f7)
by Nothing:
I want to destroy it to its last particle.
####
[2014-04-19 20:20:00](#komment5352cc6084e24)
by Nobody:
This blog is amazing. I learned so much from it. Now I can't decide whether to become an evil overlord or destroy the Earth!
####
[2014-05-11 17:18:16](#komment536fa2c8c4f8d)
by Butthole:
0=1, haha
That's like preventing conciousness by denying existance.
Dig a hole so big so that there is nothing but a whole hole.
keep em coming!
####
[2014-06-12 17:43:28](#komment5399d8b097b8d)
by Ketzer:
Mass driver method needs math correction: as you progress in removing mass from Earth, gravity will decrease, meaning each unit will require less energy to dispose of than the previous.
####
[2014-06-15 03:20:45](#komment539d02fd7c289)
by MrBubbleSS:
I thought of another one, but it's pretty much impossible. I did the math on this myself with simple kinetic energy and ignored relativistic effects (with a little bit of looking up how much energy it takes to tear the Earth apart). If a single Hydrogen-1 particle was to strike the Earth (and transfer all energy) in the neighborhood of 1.5 sextillion times the speed of light, it would break the whole thing into pieces.
####
[2014-06-15 09:32:28](#komment539d5a1ce2eac)
by qntm:
What makes you think you can ignore relativistic effects?
####
[2014-06-26 02:26:18](#komment53ab76ba79112)
by Squid:
good point Sam
there are acctually lots of ways that the earth can be destroyed that he did not put. there is a rumor of a star called nemisis that orbits in a HUGE orbit around the sun and it comed=s around about every 22mil years. there have been projects that show that something has been causing a pattern like this. there are layers of irridum in the crust and carbon-14 dating shows it comes at 22 mil year intervals. supposedly nemisis manipulates the astroid belt and the oort cloud and sends astroids towards the sun. astroids have irridium in them so that is one logical way that that happens. If we could figure out how to make nemisis move faster or replicate the effects of nemisis on the astroid belts and oort clud then we could potentially destroy the world.
####
[2014-06-26 02:29:07](#komment53ab7763162c7)
by Squid:
I honsetly cant think of other ways to destroy the world but this is a very intresting topic. i hope he posts more on this.
####
[2014-06-26 02:45:20](#komment53ab7b3089f03)
by Squid:
Ohh!!!!! i though of more!!!! If you have seen stargate then you know about replicators. they are those von neuman machines but they have things that move them around and they cant be destroyed (except for throwing them in the sun.)
The government could make a nova bomb (taking this idea from a mod from minecraft) that basically blows up and then it make the earth into a tiny ball that pulsates and eventually blows up scattering all the pieces all over the place. there could also be a virus that somehow used minerals in the earth to replicate and it wipes out the human race then it slowly eats away at the earth until all that is left is viruses floating in the vacuum of space, getting killed by cold and radiation from the sun. Hmm what else? or we could create a device that uses resources like dirt and stone to create more complex resources like iron and stuff. it would slowly use up the dirt and stuff and eventually it would have to start using the things it created to build more complex atoms. Wait... those would split when they started getting to be at the levels of thorium and stuff , therefore creating less complex atoms that it could use to create the more complex ones again. that basically means i created a freaking reactor of radioactive elements (a.k.a. A breeder reactor) that wont work then. this is so fun!!!! im only freaking 14 and im thinking of this! there could be a huge world war and we would have to move into space bacause we have caused the currents in the magma to litterally tear the earth apart!!!! this would be because the currents would be screwed up and they would cause the techtonic plates to move and they would slam into eachother so then the seawater would boil off touching the magma. then the magma would heat up the plates and they would melt. Then if we are lucky a astroid would comeby and hit it, therefore splattering it in a huge paintball effect through the solar syatem. you may get to mars with your cremated remains! i always wanted to go there!
####
[2014-06-26 03:03:04](#komment53ab7f58a102c)
by Squid:
Do you know how a paintball explodes when it hits something? this is basically the same exact thing but on a bigger scale and with magma. acctually the magma may not splatter because the vacuum of space may pull the magma all over the place because it wants to equal out the pressure or it may have a solid shell because the cold of space (which is only 3K over absoulute zero) would solidify the magma on the outside and then it would slowly solidify on the inside. i think that the first scenario is more logical because the vacuum must be equalized.
####
[2014-06-26 03:03:46](#komment53ab7f826fd9a)
by Squid:
That is the paintball effect. Oh and i like Nobody's comment up some
####
[2014-07-07 02:51:59](#komment53b9fd3fd33c3)
by DanielLC:
MrBubbleSS, using the same idea but with relativistic effects, I got a proton moving at (1-2\*10^-85)c. That's barely enough energy, and I doubt it's efficient, so you'll want to add some more energy to that. If you want to double the energy, you have to divide the distance from c by four.
####
[2014-08-08 01:27:28](#komment53e419702d244)
by Squid:
Daniel where do you work?
thats pretty intense math
####
[2014-09-16 12:03:40](#komment5418190c9cb7c)
by flewk:
Easiest way to destroy the Earth would be move it out of orbit. Most of your methods can be changed to this for a fraction of the energy/material required. You need to move it into an unstable orbit where it will collide with another planet or sun. It can also slingshot out. Intercepting the asteroid belt will probably not be enough to destroy it and might even knock it into a stable alignment given enough time.
1. Annihilated by an equivalent quantity of antimatter
6. Blown Up
Antimatter created on Earth would have to be contained by electric/magnetic fields. As the mass increases, stability becomes an issue. Generating all of it in space could be possible one day, and then using fields to direct it towards Earth.
Even if you send this ball of antimatter at the Earth, the first wave of reactions would push the rest away and knock Earth out of its orbit.
Pretty much same thing for Blown Up. It would take a lot less explosives to push the Moon into the Earth to alter its orbit. The Moon has no atmosphere to absorb the "exhaust".
Alter orbit.
5. Overspun
8. Meticulously and systematically deconstructed
10. Hurled into the Sun
Rockets won't work. All exhaust is dumped into the atmosphere, so all it would do is heat the Earth instead of adding momentum.
By the time you have deconstructed enough of the planet, its orbit would be completely different from before. As the mass gets smaller, the successive launches would account for a larger proportion of the total momentum. Also, you would only need to dig until you reached the mantle, without the crust in place, it would be cooled and the Earth would stop spinning.
For a more economical method, add rockets or rail guns to the Moon, refer to above.
PS: It isn't the friction that causes the heat, it is the fact that air has no time to move out of the way at higher speeds. This results in compression.
9. Pulverized by impact with blunt instrument
That theory proposes an impact while Earth was still forming and cooling. That theory doesn't really make sense or is extremely unlikely for other reasons.
Anywho, the Earth and moon are both much more solid now. A collision by the moon would certainly alter the orbit of the Earth. The main problem would be trying to guess how it would effect the orbit, since you only have one Moon to try it with.
Did not read the rest.
####
[2014-10-08 21:26:22](#komment54359deec5021)
by DestroyedSoul:
I would really rather have made multi billion dollar companies, and create a PMC to start my job, make the weapon of choice and then blast the shit out of this useless earth.
####
[2014-11-04 22:01:11](#komment54594ca741471)
by John:
So, you want to explode the Earth? Earth - E a r t h - E a r t h - E a r t h - E a r t h - E a r t h
####
[2014-11-28 15:25:27](#komment547893e7ceef6)
by BK:
Assuming the multiverse interpretation of quantum physics, there are an infinite number of versions of the Earth somewhere that are experiencing Total Existence Failure every moment. No need to wait.
####
[2014-12-24 22:11:16](#komment549b3a04ecdf7)
by Farmerbob1:
Put the Earth on a Diet.
Found a link here from Reddit and read over it. The Meticulous destruction and Von Neumann machine methods can be combined with orbital mechanics to create a method of destruction that would not require railgun or rocket launches.
Von Neumann machines consume the Earth, using non-equatorial regions as the source for materials. Once a significant number of machines have been built such that additional machines are difficult to supply with power, all older machines would travel to the equator as they are replaced, and begin changing the shape of the Earth from a sphere to a disk.
Once the disk is sufficiently large that materials at it's outermost surface can be pushed out of Earth orbit with little effort, opposing space elevators are built inside the disk. Two elevators would be enough. More would just let things happen faster.
Vast numbers of the Von Neumann machines would then march up the elevators carrying solids and liquids that were of little use to machine reproduction, and the elevators would push that matter into space, to eventually be collected by the Sun or other planets. The disk itself could be torn down and the component machines tossed into space. The bottom most machines are probably compressed back into near-solid metal anyway.
When the Earth has lost enough mass that it now orbits the moon, then it is no longer a planet, it's a moon.
Sure, you still have to generate all the power to make the Von Neumann machines, but you don't need massive pulses of power like railguns or rocketry. A few orbital solar mirrors to illuminate the dark side of Earth and/or increase the density of solar energy would be rather handy.
I consider this different from meticulous disassembly because it uses orbital mechanics and terraforming to create a low-power mass dispersal system.
####
[2014-12-27 02:25:05](#komment549e188158769)
by Aaron Kaufman:
Regarding the black hole colliding with, oscillating through, and finally coming to rest inside the heart's core, (See e.g., David Brin's Earth), a few comments: first, as in the book, lest it is sufficiently big to start, the heart's density vs. Hawking radiative loss will cause it to dissipate harmlessly. The book got around this by making the b.h. exotic, a particularly weird singularity with reduced Hawking emissions. Secondly, and bare in mind that I didthe math only once without checking, to cconserve earth axial-spin component of angular momentum, given it's unchanging (presumably) mass as it is consumed (more on the necessity of this assumption in light of planet killing criteria later ) , the resultant angular momentum of 9mm earth remnant will render the remnant b.h. superextremal. In lay terms, it will spin too fast for it's given mass and she'd it's event horizon, likely in physical. It's alternative would be to she'd matter which can convection away the excess angular momentum. Also, though, I disagree with the comment or who suggested the eremnant would qualify as a planet. That's problematic because such a remnant would no longer have a clean neighborhood; it will be filled with the ejecta it used to she'd it's superextremal angular momentum. It would also be extremely hot and outshine the sun, constantly emittingHawking particles from just ooutside it's e.h. And would for that reason too not have cleared its neighborhood. Finally it would have other classical forces smearing it out into a ring--if we consider the singularity the remnant--or a somewhat eccentric oblate Sherwood rather than something I'd call round. This presumes it still has a fair amount of angular momentum, which is likely.
####
[2015-01-10 13:37:40](#komment54b12b2455166)
by Martijn Krakeel:
One could "just" convince the world's population of the necessity of Earth's destruction and command every one to shovel up it's material, dirt-soil-earth you name it, put it in plenty of rockets and fire them of into space and then commit collective suicide.
Obviously you will run out of both working space and at a certain time so automation is essential. These automatons need repair bots AND need all to be set with self destructive devices to get rid of them. All this will eventually result in lack of atmosphere, gravity and the Earth's soil and therefore it's existence.
The biggest problem is convincing people this really is what needs to be done...
####
[2015-01-10 13:39:49](#komment54b12ba549d8c)
by Martijn Krakeel:
About comment above:
"...working space and WORKERS at a certain time..."
####
[2015-01-10 22:06:27](#komment54b1a26360e0d)
by Primal Light:
You wouldn't need to turn half of the EARTH into antimatter, just half of the CORE. Doing so would shatter the planet AND get rid of the core's gravity. By sending all the pieces far away from each other, you would reduce gravity enough that the atmosphere would not stay on ANY of the pieces, therefore exterminating all life on Earth reliant of oxygen or protection from the Sun's radiation (which is usually blocked by a combination of the atmosphere and the Earth's magnetic field... which is produced by the core).
####
[2015-01-30 09:12:33](#komment54cb4b012ea89)
by the world safer anonymus:
GOOGLE GOES MAD THIS PAGE IS PROBABLY OK BUT ANYTHING OTHER WILL DESTROY THE WORLD!
####
[2015-02-03 20:19:14](#komment54d12d42907a5)
by D. Zoom:
Ok going to explain this out really easy in as simple terms posable.
Gravity Well Bomb (GWB) For minning.
Dont even bother reading this unless you understand advanced math.
Ok going to explain this out really easy in as simple terms as able to.
First off triangle. The strongest shape going. So a 1 foot triangle with three rods, one in each corner. On each rod 3 dumb bell shape weights hooked up to a gear on each. Made so the weight can spin around while on the rod. Maybe a foot tall for each rod. One weight near the bottom close to the triangle. One weight in the middle of the rod and one weight near the top. Maybe abec bearings to make the weights spin faster.
Top and bottom weight must spin the same way and middle weight must spin the other direction. Otherwise you have a completely different device.
Hook up gears on weights to a means to make them spin. Either a bike chain hooked up to a small engine or use other gears hooked up to a small engine. May want to use three small engines, one for each tier of spinning weights. Each tier will have three weights. So you will have a total of 9 weights spinning. Also you will want to run a current of electricity threw the rods.
In the center of the triangle raised up to the level of the middle weights put a ruby with a way to strike it with a needle very hard and fast. So the ruby fractures and makes the desired sound.
Ok Currents causes a electromagnetic field.
Weights cause a gravity well
Ruby cause the vibration inside the well.
So spinning weights explained. Getting them to spin at about the power of 1 will give you a total power of 3 in the center.
Look at it this way. if you take a pal of water and put it on its side the water falls out
But if you spin the same pal of water around faster and faster slowly bringing it up the pal will be at its side and the water will not fall out.
So basicly you are looking at you arm to the end of the bucket being the length.
Then the weight of the water.
The rpm that it takes to spin it around and keep it in the bucket.
now doing this with the weight works the same way but no water. The ends of the weights have the gravity force of 1 ok. You can't see this force but it is there.
Now with all three weight spinning you have a total of 3 on top and 3 on the bottom holding in the 3 in the middle. The top and bottom will run off up and down but will keep pressure on the one in the middle. The well in the middle will become stable.
So if you have a 1 foot well that would be from the center of the weights to the center of the triangle.
Ok so maybe you have already learned the take a 1 foot balloon into the water thing but I will explain it again. If you blow up a balloon to 1 foot in size and take it down 33 feet of water it will be 1/2 its size due to the pressure. Another 33 feet and its a 1/4 its size. so yet another will make it 1/8 its size.
So 1, 1/2 2, 1/4 3, 1/8 4, 1/16 5, 1/32 6, 1/64 7, 1/128 8, 1/246 9, 1/542 10, 1/1082 11, 1/2164 12, 1/4328 13, 1/ 8656 14, 1/17312 etc etc. you see how its builds up.
If there are 5280 feet in a mile then at 14 atm thats over 3 miles. that little 1 foot balloon would want to grow to the size of.
You are now pushing in on the center well with 3 atm like this. So that 1 foot gravity well will want to expand to 8 times its size.
The current will charge the atoms.
Striking the ruby in the center will cause a tone that it takes to fracture a lv ten stone. Different sounds different results. Very usable for mining to remove lesser stones. A level 8 stone will leave behind all level 9-10
After the stone is stuck the sound wave given of from it will shake the atoms in the given space going back and forth over and over till in the weights and rods break apart. The electric charge will demagnetize the atoms. The rods will shatter and the well will be released. Everything in a 8 foot area will be shaken apart to a single atom state in a perfect circle from the center of the triangle.
Atoms take a short time to repolarize and reform material.
Putting a faster spin on things will give larger results.
Do not use light instead of sound. Sound at least stops at space. Light dose not and burns the atoms.
####
[2015-02-06 20:00:48](#komment54d51d703c620)
by ThinkingMan:
Wait ! Wait is the word. And this word will destroy Earth.
When the Sun is going to die, he will destroy earth and others planets very easely.
Don't need humans to do it ! Of course human will be dead looooooooonnnnngggg time before that !
####
[2015-03-10 05:24:17](#komment54fe80019bc53)
by The One Who Bides His Time:
Whoever wrote this took to much time and effort into it. I already have the equipment for Pyra, Jake Hopper, and I (CodeNames) to rip the earth apart by quite literally jumping dimensions. I don't care what anyone thinks they know, but I have put Five years seven months and twentyeight days working on a machine base that could make more than time travel possible. Whoever reprots this will be found and sent away. If you all care about this earth, do not open the void.
From the one and only
- Rift Breaker
####
[2015-03-24 23:11:39](#komment5511ef2bdf396)
by Professor Chaos:
Don't need to completely destroy it, just wipe it clean and turn it into a molten ball of magma. So long as humans are gone. And no escape route, all humans must be removed.
####
[2015-05-16 22:52:06](#komment5557adf6b5844)
by Dr. van Something:
Professor Chaos has the right of it, I think. Most people who talk in a serious vein about "destroying the world" are speaking metonymously about the destruction of all SAPIENT LIFE on Earth (and sometimes all even remotely sentient life as well, just to be sure). This remains the case regardless of whether they believe such destruction is inherently good or merited -- you may be saying "I am going to destroy the world" or "That madman's going to destroy the world", but in either case what you really mean is "destroy the human race".
####
[2015-05-18 10:37:38](#komment5559a4d237cb2)
by Ofir Ben Yashar:
Haha.
Why would you destroy Earth?
It's such a beautiful place.
Besides don't you feel selfish?
You literally decide for other people to die.
Maybe they don't want to die?
You're not a god.
If they want to live their life they will live it.
If not, They will find their way to commit a suicide.
Who are you to say that earth should be destroyed.
I just don't get people.
This world is a f#cking gift, who knows maybe your next avatar will be born as a fucking cat on the street with no food.
Maybe after you die. nothing comes up a head.
So try to enjoy now the life you're living as a human. And don't even think about destroying what god gave you.
You fools.
####
[2015-06-02 01:23:12](#komment556ce960cc104)
by Morfos:
By the definitions at the start of this article, one could destroy the earth by making it cubical...shave off bits here, dump them there, until it's no longer "generally round".
####
[2015-06-03 14:40:53](#komment556ef5d5af4df)
by Scott Brooks :
I'm writing about the Hadron Collide and If the moon was strucked by it during its apogees cycle. What would be the effect?
####
[2015-06-03 14:57:11](#komment556ef9a7ebadc)
by Scott Brooks:
I'm sorry, as stupid as it sounds. My remodel of the remake space 1999. The moon was taken out of earth's orbit by a massive nuclear explosion. I knew nuclear methods couldn't be used but then I thought of the Hadron Collider. Since I should understand the physics of this possibility, I should try to understand it.
####
[2015-07-22 12:37:20](#komment55af7260b4d4d)
by Ofir Ben Yashar:
https://www.youtube.com/watch?v=sHC7BRRrqo4
This discussion is closed.
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<head>
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<a href="index.htm">back</a><br><br>
<b>DIY $10 Overflow Box</b><br><br>
I just wanted to try hooking up my aquarium to another small one as a refugium, and i dont need a huge flow rate or a huge gygantic overflow box hanging over my aquarium. I came up with this idea to use a gravel vacuum and a jar to make an overflow box. So here you go:
<br><br>
To make a $10 overflow, here are the materials:<br><br>
1 Gravel Vacuum with hose (cost ~$10) <br>
1 Thin cup like thing (I used a spice jar)<br><br><br>
All you do is put the jar down the cylinder, and feed the tube coming from the overflow inside your aquarium into the jar. The jar will preserve the cyphon, and water just flows over it and down the cylinder!
I added some plastic bits underneith to keep the jar from falling right to the bottom, but you could use a sponge as a prefilter or marbles to improve 02 levels. If you need a tube to go from the overflow on the back to the one inside your aquarium you can just cut a small length off your gravel vacuum tube.<br><br>
Now to make things a little better with a bit more money, it might be a good idea to seal the cylinder and the green cap with some silicon. You might also need to add elbows as I eventually did to keep things sturdy. I used air-tube holders I had lying around and zip-ties as a way to fasten the overflow and return line to the aquarium.<br><br>
Here are some pics:<br><br>
The overflow box .. er overflow cylinder<br>
<img src="diy/diyof.jpg" o:title="tank"/><br><br>
Overflow box with marbles (there is also an upside down plant pot separating the marbles from the drain)<br>
<img src="diy/o2.jpg" o:title="tank"/><br><br>
The overflow that leads to the overflow box, made out of a spent bottle of Buckleys with holes drilled into it, fastened with zipties to an air-tube holder and that made it adjustable :D <br>
<img src="diy/cyphon.jpg" o:title="tank"/><br><br>
Heres the return to the big tank<br>
<img src="diy/return.jpg" o:title="angle"/><br><br>
The small pump whirring away in the smaller tank<br>
<img src="diy/workhorse1.jpg" o:title="angle"/><br><br>
This is a drawing of how the cyphon is maintained<br>
<img src="diy/overflow.gif" o:title="angle"/><br><br>
So for the cost of the entire flow system:<br><br>
<b>overflow box: $10</b><br>
pump: $20<br>
aquarium safe silicon $7 (used only a tiny bit of it)<br>
3 elbows $3<br>
tube for return $3<br><br>
Total: $43 cdn<br><br>
<a href="index.htm">back</a> |
DIY
[back](index.htm)
**DIY $10 Overflow Box**
I just wanted to try hooking up my aquarium to another small one as a refugium, and i dont need a huge flow rate or a huge gygantic overflow box hanging over my aquarium. I came up with this idea to use a gravel vacuum and a jar to make an overflow box. So here you go:
To make a $10 overflow, here are the materials:
1 Gravel Vacuum with hose (cost ~$10)
1 Thin cup like thing (I used a spice jar)
All you do is put the jar down the cylinder, and feed the tube coming from the overflow inside your aquarium into the jar. The jar will preserve the cyphon, and water just flows over it and down the cylinder!
I added some plastic bits underneith to keep the jar from falling right to the bottom, but you could use a sponge as a prefilter or marbles to improve 02 levels. If you need a tube to go from the overflow on the back to the one inside your aquarium you can just cut a small length off your gravel vacuum tube.
Now to make things a little better with a bit more money, it might be a good idea to seal the cylinder and the green cap with some silicon. You might also need to add elbows as I eventually did to keep things sturdy. I used air-tube holders I had lying around and zip-ties as a way to fasten the overflow and return line to the aquarium.
Here are some pics:
The overflow box .. er overflow cylinder
![](diy/diyof.jpg)
Overflow box with marbles (there is also an upside down plant pot separating the marbles from the drain)
![](diy/o2.jpg)
The overflow that leads to the overflow box, made out of a spent bottle of Buckleys with holes drilled into it, fastened with zipties to an air-tube holder and that made it adjustable :D
![](diy/cyphon.jpg)
Heres the return to the big tank
![](diy/return.jpg)
The small pump whirring away in the smaller tank
![](diy/workhorse1.jpg)
This is a drawing of how the cyphon is maintained
![](diy/overflow.gif)
So for the cost of the entire flow system:
**overflow box: $10**
pump: $20
aquarium safe silicon $7 (used only a tiny bit of it)
3 elbows $3
tube for return $3
Total: $43 cdn
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<A HREF="http://www.hopspress.com/Books/Botany_in_a_Day.htm"><IMG SRC="http://www.hopspress.com/Books/Coverpics/Botany.jpg" ALT="Botany in a Day: The Patterns Method of Plant Identification" WIDTH="108" HEIGHT="140" ALIGN=RIGHT VSPACE="5" HSPACE="5"></A>
<P ALIGN=LEFT><FONT SIZE="2"><B> "Many people are familiar with the square stems and opposite leaves of the plants in the Mint Family. I like to start my classes with a discussion of the mints because this pattern is so well known. <BR><BR>
"What people don't realize is that similar patterns exist for other families of plants as well. You only need to learn about 100 broad patterns to recognize something about virtually every plant from coast to coast across the northern latitudes.<BR><BR>
"In a two hour plant walk we typically start with the Mint Family, then progress through the Mustard, Pea, Parsley, Borage, Lily, and Aster Families, so that every student can easily recognize these common families representing several thousand species. <BR><BR>
I've had people tell me they learned more in that two hour walk than in an entire semester of botany in college."</B></FONT></P>
<P ALIGN=RIGHT><FONT SIZE="2"><B>--Thomas J. Elpel, Author<BR><A HREF="http://www.hopspress.com/Books/Botany_in_a_Day.htm">Botany in a Day</A></B></FONT></FONT></P></TD></TR></TABLE>
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<IMG SRC="images/Tom_Cattails.jpg" ALT="Thomas J. Elpel gathering Cattails." ALIGN=LEFT WIDTH="200" HEIGHT="300" VSPACE="5" HSPACE="5">
<IMG SRC="images/Tom_and_Edwin.jpg" ALT="Thomas J. Elpel and son trimming Cattails." ALIGN=RIGHT WIDTH="200" HEIGHT="300" VSPACE="5" HSPACE="5">
<P ALIGN=CENTER><FONT SIZE="2"><B>Updated!</B> Now with 1,000+ pictures on-line.</FONT><BR><FONT SIZE="3"><B>Wildflower Photo Gallery</B></FONT><BR><FONT SIZE="2"><B><A HREF="http://www.wildflowers-and-weeds.com/Plant_Families/Plant_Families_Index.html">Identify your Wildflowers!</A></B></FONT></P>
<P ALIGN=CENTER><FONT SIZE="2">Want to learn to identify 45,000 plants today?</FONT><BR><FONT SIZE="3"><B>Be sure to read my on-line article</B></FONT><BR><FONT SIZE="2"><B><A HREF="http://www.wildflowers-and-weeds.com/Plant_Identification/Patterns_in_Plants.htm">Learning to Identify Plants by Families</A></B><BR><B><A HREF="http://www.botanyeveryday.com" target="blank">Participate in an On-Line Class</A></B></FONT><BR><FONT SIZE="1"><A HREF="Frank_Cook_Memorial.htm">Frank Cook Memorial 1963 - 2009</A></FONT></P>
<P ALIGN=CENTER><FONT SIZE="3"><B>Plant Identification Resources </B></FONT><BR><FONT SIZE="2"><B><A HREF="Plant_Identification/index.html#Books">Books Recommended by Tom</A></B></FONT></P>
<P ALIGN=CENTER><FONT SIZE="3"><B>Wild Edible Plants</B></FONT><BR><FONT SIZE="2"><B><A HREF="http://www.wildflowers-and-weeds.com/Edible_Plants/index.html">Resources for the Wild Food Enthusiast</A></B></FONT></P>
<P ALIGN=CENTER><FONT SIZE="3"><B>Special Features</B></FONT><BR><FONT SIZE="2"><B><A HREF="http://www.wildflowers-and-weeds.com/Plant_Identification/New_Zealand/index.html">Botanizing New Zealand</A></B><BR>Six Pages and 130 Photos from Down Under<BR>
<B>NEW! <A HREF="http://www.wildflowers-and-weeds.com/Plant_Identification/Sweden/index.html">Botanizing Sweden</A></B><BR>Six Pages and 170 Photos!</FONT></P>
<P ALIGN=CENTER><FONT SIZE="3"><FONT SIZE="2"><B><A HREF="http://www.elpel.info/Articles//Dry_Cold_Permaculture.htm">Dry Cold Permaculture: Homesteading in the Northern Rockies</A></B></FONT></P>
<HR>
<FONT SIZE="2"><I>Dear Tom,</I><BR><BR>
<A HREF="http://www.hopspress.com/Books/Botany_in_a_Day.htm"><IMG SRC="http://www.hopspress.com/Books/Coverpics/Botany.jpg" ALT="Botany in a Day: The Patterns Method of Plant Identification" WIDTH="108" HEIGHT="140" ALIGN=RIGHT VSPACE="5" HSPACE="5"></A>
<I>My husband brought me a copy of <A HREF="http://www.hopspress.com/Books/Botany_in_a_Day.htm">Botany in a Day</A> and I wish I'd had it when I started my love affair with wild plants! (Of course, you weren't born yet...) This is THE best-laid-out teaching guide to plants I have ever seen, and my library of botanical texts is in the100's! I plan to use it as a textbook for serious students of botany. <BR><BR>
I wish we had something equivalent for Missouri, although your estimate of 75% species occurrence of western species in Missouri is quite valid. We are quite the ecosystem-crossroads here! Steyermark's Flora of Missouri is wonderful but enormous and unwieldy, and our Dept. of Conservation and Dept. of Natural Resources folks have good general field guides for beginners. But your book is outstanding! Keep up the excellent work! </I></FONT></P>
<P ALIGN=RIGHT><FONT SIZE="2"><I>Most sincerely,<BR>
Laurie Lovell, aka Wild Plant Woman</I></FONT></P>
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<P ALIGN=LEFT><FONT SIZE="2"><B><I> Looking for life-changing resources?</I> Check out these books by Thomas J. Elpel:</I></B></FONT><BR>
<TABLE ALIGN=CENTER WIDTH="710" CELLSPACING="5" BORDER="0" CELLPADDING="0" VSPACE="5" HSPACE="5" BGCOLOR="#FFFFFF" BACKGROUND="http://www.wildflowers-and-weeds.com/menus/images/BKGRD.Lilacs.jpg">
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<TD WIDTH="80" ALIGN=CENTER VALIGN=TOP><FONT FACE="arial,helvetica,espy,sans-serif"><A HREF="http://www.hopspress.com/Books/Roadmap_To_Reality.htm"><IMG SRC="http://www.hopspress.com/Books/Coverpics/Roadmap.108W.jpg" ALT="Roadmap to Reality: Consciousness, Worldviews, and the Blossoming of Human Spirit" WIDTH="80" HEIGHT="103"></A><BR><FONT SIZE="1"><A HREF="http://www.hopspress.com/Books/Roadmap_To_Reality.htm">Roadmap<BR> to Reality</A></FONT></FONT></TD>
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Wildflowers and Weeds: Identify plants, flowers, and weeds with Botany in a Day!
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**Botany in a Day****The Patterns Method of Plant Identification**
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**Parsley Family Slideshow:** **Notice the pattern of similarity among these different species of the same family. (If the slideshow doesn't appear then try a newer browser.)**
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[Botany in a Day: The Patterns Method of Plant Identification](http://www.hopspress.com/Books/Botany_in_a_Day.htm)
**"Many people are familiar with the square stems and opposite leaves of the plants in the Mint Family. I like to start my classes with a discussion of the mints because this pattern is so well known.
"What people don't realize is that similar patterns exist for other families of plants as well. You only need to learn about 100 broad patterns to recognize something about virtually every plant from coast to coast across the northern latitudes.
"In a two hour plant walk we typically start with the Mint Family, then progress through the Mustard, Pea, Parsley, Borage, Lily, and Aster Families, so that every student can easily recognize these common families representing several thousand species.
I've had people tell me they learned more in that two hour walk than in an entire semester of botany in college."**
**--Thomas J. Elpel, Author[Botany in a Day](http://www.hopspress.com/Books/Botany_in_a_Day.htm)** |
---
Thomas J. Elpel gathering Cattails.
Thomas J. Elpel and son trimming Cattails.
**Updated!** Now with 1,000+ pictures on-line.**Wildflower Photo Gallery****[Identify your Wildflowers!](http://www.wildflowers-and-weeds.com/Plant_Families/Plant_Families_Index.html)**
Want to learn to identify 45,000 plants today?**Be sure to read my on-line article****[Learning to Identify Plants by Families](http://www.wildflowers-and-weeds.com/Plant_Identification/Patterns_in_Plants.htm)****[Participate in an On-Line Class](http://www.botanyeveryday.com)**[Frank Cook Memorial 1963 - 2009](Frank_Cook_Memorial.htm)
**Plant Identification Resources** **[Books Recommended by Tom](Plant_Identification/index.html#Books)**
**Wild Edible Plants****[Resources for the Wild Food Enthusiast](http://www.wildflowers-and-weeds.com/Edible_Plants/index.html)**
**Special Features****[Botanizing New Zealand](http://www.wildflowers-and-weeds.com/Plant_Identification/New_Zealand/index.html)**Six Pages and 130 Photos from Down Under
**NEW! [Botanizing Sweden](http://www.wildflowers-and-weeds.com/Plant_Identification/Sweden/index.html)**Six Pages and 170 Photos!
**[Dry Cold Permaculture: Homesteading in the Northern Rockies](http://www.elpel.info/Articles//Dry_Cold_Permaculture.htm)**
---
*Dear Tom,*
[Botany in a Day: The Patterns Method of Plant Identification](http://www.hopspress.com/Books/Botany_in_a_Day.htm)
*My husband brought me a copy of [Botany in a Day](http://www.hopspress.com/Books/Botany_in_a_Day.htm) and I wish I'd had it when I started my love affair with wild plants! (Of course, you weren't born yet...) This is THE best-laid-out teaching guide to plants I have ever seen, and my library of botanical texts is in the100's! I plan to use it as a textbook for serious students of botany.
I wish we had something equivalent for Missouri, although your estimate of 75% species occurrence of western species in Missouri is quite valid. We are quite the ecosystem-crossroads here! Steyermark's Flora of Missouri is wonderful but enormous and unwieldy, and our Dept. of Conservation and Dept. of Natural Resources folks have good general field guides for beginners. But your book is outstanding! Keep up the excellent work!*
*Most sincerely,
Laurie Lovell, aka Wild Plant Woman*
---
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***Looking for life-changing resources?* Check out these books by Thomas J. Elpel:**
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| [Green Prosperity: Quit Your Job, Live Your Dreams.](http://www.hopspress.com/Books/Green_Prosperity.htm)[GreenProsperity](http://www.hopspress.com/Books/Green_Prosperity.htm) | [Roadmap to Reality: Consciousness, Worldviews, and the Blossoming of Human Spirit](http://www.hopspress.com/Books/Roadmap_To_Reality.htm)[Roadmap to Reality](http://www.hopspress.com/Books/Roadmap_To_Reality.htm) | [Living Homes: Stone Masonry, Log, and Strawbale Construction](http://www.hopspress.com/Books/Living_Homes.htm)[Living Homes](http://www.hopspress.com/Books/Living_Homes.htm) | [Participating in Nature: Wilderness Survival and Primitive Living Skills.](http://www.hopspress.com/Books/Participating_in_Nature.htm)[Participating in Nature](http://www.hopspress.com/Books/Participating_in_Nature.htm) | [Foraging the Mountain West: Gourmet Edible Plants, Mushrooms, and Meat.](http://www.hopspress.com/Books/Foraging_The_Mountain_West.htm)[Foraging theMountain West](http://www.hopspress.com/Books/Foraging_The_Mountain_West.htm) | [Botany in a Day: The Patterns Method of Plant Identification](http://www.hopspress.com/Books/Botany_in_a_Day.htm)[Botany in a Day](http://www.hopspress.com/Books/Botany_in_a_Day.htm) | [Shanleya's Quest: A Botany Adventure for Kids](http://www.hopspress.com/Books/Shanleya's_Quest.htm)[Shanleya's Quest](http://www.hopspress.com/Books/Shanleya's_Quest.htm) |
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<b class="disclaimer">Disclaimer:</b> Glassblowing has inherent hazards that can result in burns, cuts, injuries or even death. While every effort has been made to convey best safety practices, the materials presented herein can not anticipate every possible risk or hazard associated with a given glassblowing activity. The reader is responsibile for assessing and mitigating any and all such hazards or risks before commencing any activity connected with his or her use of these materials. Neither the author nor ILPI assumes responsibility or liability for injuries, losses, claims or damages to the reader or other parties that may result from the use or misuse of these materials.
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**General Information**
[About This Site](history.html)
[What is scientific glassblowing?](glassblowing.html)
[Glass workshop tour](shoptour.html)
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**Glassblowing Tools**
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[Hand Tools](glassblowertools.html)
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[Rosedidymium Eyeglasses](rosedidymium.html)
**Tips and Info**
[Tables, data and technical resources](techdata.html)
[Glass flange fixture](glassflange.html)
[Frozen joints](frozenglass.html)
[Pressure nomograph](glasspressures.html)
[Historical recipes](oldrecipes.html)
[Quartz maria](quartzmaria.html)
[Glass shop design](shopdesign.html)
[Miscellaneous tips and tricks](tips.html)
**Basic Tutorials**
1. [Introduction, objectives and safety](tutorial_intro.html)
2. [Terminology]( tutorial_terms.html)
3. [The glassblower's bench](tutorial_bench.html)
4. [Oxygen and fuel gas systems](tutorial_gases.html)
5. [Burners and torches](tutorial_burners.html)
6. [Cutting glass](tutorial_cutting.html)
7. [Rotating glass](tutorial_rotation.html)
8. [Fire polishing](tutorial_firepolish.html)
9. [Annealing](tutorial_annealing.html)
10. [Making a test tube](tutorial_testtube.html)
11. [Butt seals](tutorial_buttseal.html)
12. [T seals](tutorial_tseal.html)
13. [Bending glass](tutorial_bends.html)
14. [Sealing Ampules](tutorial_ampule.html)
15. [Repairs](tutorial_repairs.html)
16. [Ring Seals](tutorial_ringseal.html) (Advanced)
17. [Silvering Glass](tutorial_silvering.html) (Advanced)
---
**Disclaimer:** Glassblowing has inherent hazards that can result in burns, cuts, injuries or even death. While every effort has been made to convey best safety practices, the materials presented herein can not anticipate every possible risk or hazard associated with a given glassblowing activity. The reader is responsibile for assessing and mitigating any and all such hazards or risks before commencing any activity connected with his or her use of these materials. Neither the author nor ILPI assumes responsibility or liability for injuries, losses, claims or damages to the reader or other parties that may result from the use or misuse of these materials.
This page and any associated material is [copyright](../copyright.html) 2002-2023 by Joe Walas and/or ILPI unless otherwise stated. Unauthorized duplication or posting on other web sites is expressly prohibited. Send suggestions and comments (include the URL if applicable) to us [by email](../contact.html).
| http://www.ilpi.com/glassblowing/ |
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<nobr><font color="yellow"><b>Home</b></font> |</nobr>
<nobr><a href="http://www.RobotsAndComputers.com/robots/personal.htm">Personal Collection</a> |</nobr>
<nobr><a href="http://www.RobotsAndComputers.com/robots/others.htm">Wanted List</a> |</nobr>
<nobr><a href="http://www.RobotsAndComputers.com/robots/remotes.htm">Remote Controls</a> |</nobr>
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<font color="yellow"><b><i>Robots in Collection:</i></b></font><br>
<font color="white"> 122</font>
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<img src="images/ist2_1894798.gif" width="300">
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<!-- ROBOTS ON WISHLIST -->
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<font color="yellow"><b><i>Robots on Wish List:</i></b></font><br>
<font color="white"> 11</font>
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<p class="body">
Welcome to THE Robot Hot Spots on the internet! <br>
<font color="white">
Before I forget, be sure to check out my 3D Print Models
<strike>here on my Thingiverse account.</strike> Well... Thingiverse has banned me
with no explanation. That's ok, though because that site has been going down the
drain for over a year now and it is hemorrhaging users left and right. Visit me on
<a href="https://www.myminifactory.com/users/rebeltaz" >MyMiniFactory</a>
and <a href="https://cults3d.com/en/users/rebeltaz/creations" >Cults3d</a>,
both of which care about their users.
</font>
</p>
<p class="body">
Then you can peruse my
<a href="personal.htm">Personal Robot Collection</a> and my
<a href="others.htm">Wish-List</a>, but I have tried to make
each Robot Personality Page as complete and informative as
possible. If you are here for computers, then you would be wanting the
<a href="../computers/index.htm">Computer Division</a>.
Go figure, huh?
</p>
</td>
</tr>
<tr>
<td align="justify" width="100%" colspan="2">
<p class="body">
Then you can head on over to my <a href="books.htm">Book
Collection</a> to get an idea of the wonderful books
available on robots and robot building. Next you'll want to
check out the <a href="projects.htm">"Build Your Own"</a>
section to get an idea for your next robot project.
</p>
</td>
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<br>
<a href="http://rebeltaz.ioffer.com" target="_blank">
<img src="images/robot$.gif" width="60" border="0">
</a>
</td>
<td align="justify" width="85%">
<p class="body">
We are making and selling (for very little profit,
I might add) handmade wooden Nativity Sets. You can
see more details on our
<a href="http://www.RobotsAndComputers.com/NativityProject">Nativity Project Page</a>.
</p>
<p class="body">
To see the few robots that I have for sale, check out my
<a href="http://rebeltaz.ioffer.com"
target="_blank"> iOffer Web Store</a>.
</p>
<p class="body">
In addition to robots, computers, electronics and book, I
also do some woodworking.
<a href="http://RobotsAndComputers.com/frenchie.htm">On
this page</a> you can see a couple of servants that we
have built and are offering for sale.
</p>
</td>
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-->
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<hr color="yellow" width="75%">
</td>
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<td align="justify" width="100%" colspan="2">
<p class="body">
If you are here about TGIMBOEJ project (or you're just
curious about what all of them there letters stand for)
jump on over to <a href="tgimboej.htm">this page</a>.
</p>
</td>
</tr>
<tr>
<td align="center" width="100%" colspan="2">
<hr color="yellow" width="75%">
</td>
</tr>
</table>
<table border="0" width="90%" align="center">
<tr>
<td align="justify" width="85%">
<p class="body">
I am happy to announce that, with the help of a Pocket
PC, you can now control ALL of your infrared robots
without the need for multiple remotes! As we share our
own IR codes, I hope to be able to host the codes for
every infrared robot ever made.
<a href="IRremotes.htm">Click here</a> to check out our
latest project...
</p>
</td>
<td align="center" width="15%">
<img src="images/remote_sm.gif" width="75">
</td>
</tr>
<tr>
<td align="center" width="100%" colspan="2">
<hr color="yellow" width="75%">
</td>
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<p class="body" style="text-align: center; color: #4F0D12">
And Don't Forget to Visit<br>
<a href="http://www.ShelbyCycle.com" target="_blank">
<img src="http://www.ShelbyCycle.com/ShelbyCycle_logo_icon.png"
alt="ShelbyCycle.com" title="Shelby Cycle" border="0" align="middle"></a>
and
<a href="http://www.ShelbyTVService.com" target="_blank">
<img src="http://www.ShelbyTVService.com/ShelbyTV_logo_icon.png"
alt="ShelbyTVService.com" title="Shelby TV Service" border="0" align="middle"></a>
<br>
We Need the Money! :)
</p>
<hr width="55%" color="white">
<p class="body" style="margin: 18px 10%">
Speaking of money... running (and stocking) this virtual musem
does take money. Since I hate all those freaking advertisements,
I refuse to run them. That is why I am printing this request at
the bottom of this page. I do all of this out of my own pocket as
a labor of love, but if everyone who visited were able to donate
even a single dollar, there would be more than enough to defray
the electric and internet costs as well as to purchase more robots
and computers to add to the collection. And of course, robotic
and computer donations are always welcome...
</p>
<center>
You Can Donate By Clicking the Button Below<br>
<form action="https://www.paypal.com/cgi-bin/webscr" method="post">
<input type="hidden" name="cmd" value="_s-xclick">
<input type="hidden" name="hosted_button_id" value="4DYL4GFA3UMRC">
<input type="image" src="https://www.paypalobjects.com/en_US/i/btn/btn_donate_LG.gif" border="0" name="submit" alt="PayPal - The safer, easier way to pay online!">
<img alt="" border="0" src="https://www.paypalobjects.com/en_US/i/scr/pixel.gif" width="1" height="1">
</form>
</center>
<p class="body" style="margin: 18px 10%">
Or, if you'd like, you are welcome to donate via Bitcoin: <br>
<font color="white">
<img src="images/logo_bitcoin16x16.gif"> 1AekYh7gP2ZEHNM1r9TtmSZ5NemmoKmHNx</font>
</p>
<br>
<hr width="35%" color="green">
<br>
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<b><i><font size="1">
Designed for the Best Viewing Experience on<br>
<img src="../images/logo_firefox.png" align="middle">
<a href="http://www.mozilla.com/firefox/" target="_blank">Mozilla Firefox</a><br>
...pages may not display correctly on Google- or Microsoft-based software...
</font></i></b>
</p>
<br>
<p align="center">
<b><i><font size="1">
For the Ultimate in Safe, Anonymous Web Searching... ditch Google.<br>
Try the Search Engine with the Funny Name - <br>
<img src="images/logo_ddg.png" width="48" align="middle">
<a href="https://duckduckgo.com/" target="_blank">DuckDuckGo.com</a></br>
"The Search Engine That Doesn't Track You"
</font></i></b>
</p>
<br>
<p align="center">
<b><i><font size="2">
<!--"../counter/counter.php?page=robots&digit=bbldotg"-->
<img src="../counter/counter.php?page=robots&digit=ocr"
border="0" hspace="7" align="middle">
Visitors Since We Went Online
</font></i></b>
</p>
<hr width="35%" color="#302D96">
<p align="center">
<b><i><font size="1">
Powered By
<a href="http://www.ubuntu.com" target="_blank"><img hspace="2" src="images/logo_ubuntu.gif" align="middle" border="0"></a>
&
<a href="http://www.apache.org" target="_blank"><img hspace="2" src="images/logo_apache.gif" align="middle" border="0"></a>
</font></i></b>
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</td>
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|
Robots and Computers - Robot Division
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| --- |
|
[www.RobotsAndComputers.com](http://www.RobotsAndComputers.com/index.htm) |
|
**Home** |
[Personal Collection](http://www.RobotsAndComputers.com/robots/personal.htm) |
[Wanted List](http://www.RobotsAndComputers.com/robots/others.htm) |
[Remote Controls](http://www.RobotsAndComputers.com/robots/remotes.htm) |
[Books](http://www.RobotsAndComputers.com/robots/books.htm) |
[Owner's Manuals](http://www.RobotsAndComputers.com/robots/manuals.htm) |
[Projects](http://www.RobotsAndComputers.com/robots/projects.htm) |
[Links](http://www.RobotsAndComputers.com/robots/links.htm) |
[Computer Division](http://www.RobotsAndComputers.com/computers/index.htm) |
[Search](http://www.RobotsAndComputers.com/robots/search.htm) |
[Blog](http://www.RobotsAndComputers.com/blog) |
[Contact Us](http://www.RobotsAndComputers.com/robots/contact.htm)
|
| | | |
| --- | --- | --- |
| ***Robots in Collection:***
122 | | ***Robots on Wish List:***
11 |
| |
| --- |
|
Welcome to THE Robot Hot Spots on the internet!
Before I forget, be sure to check out my 3D Print Models
here on my Thingiverse account. Well... Thingiverse has banned me
with no explanation. That's ok, though because that site has been going down the
drain for over a year now and it is hemorrhaging users left and right. Visit me on
[MyMiniFactory](https://www.myminifactory.com/users/rebeltaz)
and [Cults3d](https://cults3d.com/en/users/rebeltaz/creations),
both of which care about their users.
Then you can peruse my
[Personal Robot Collection](personal.htm) and my
[Wish-List](others.htm), but I have tried to make
each Robot Personality Page as complete and informative as
possible. If you are here for computers, then you would be wanting the
[Computer Division](../computers/index.htm).
Go figure, huh?
|
|
Then you can head on over to my [Book
Collection](books.htm) to get an idea of the wonderful books
available on robots and robot building. Next you'll want to
check out the ["Build Your Own"](projects.htm)
section to get an idea for your next robot project.
|
|
---
|
|
If you are here about TGIMBOEJ project (or you're just
curious about what all of them there letters stand for)
jump on over to [this page](tgimboej.htm).
|
|
---
|
| | |
| --- | --- |
|
I am happy to announce that, with the help of a Pocket
PC, you can now control ALL of your infrared robots
without the need for multiple remotes! As we share our
own IR codes, I hope to be able to host the codes for
every infrared robot ever made.
[Click here](IRremotes.htm) to check out our
latest project...
| |
|
---
|
And Don't Forget to Visit
[ShelbyCycle.com](http://www.ShelbyCycle.com)
and
[ShelbyTVService.com](http://www.ShelbyTVService.com)
We Need the Money! :)
---
Speaking of money... running (and stocking) this virtual musem
does take money. Since I hate all those freaking advertisements,
I refuse to run them. That is why I am printing this request at
the bottom of this page. I do all of this out of my own pocket as
a labor of love, but if everyone who visited were able to donate
even a single dollar, there would be more than enough to defray
the electric and internet costs as well as to purchase more robots
and computers to add to the collection. And of course, robotic
and computer donations are always welcome...
You Can Donate By Clicking the Button Below
Or, if you'd like, you are welcome to donate via Bitcoin:
1AekYh7gP2ZEHNM1r9TtmSZ5NemmoKmHNx
---
***Designed for the Best Viewing Experience on
[Mozilla Firefox](http://www.mozilla.com/firefox/)
...pages may not display correctly on Google- or Microsoft-based software...***
***For the Ultimate in Safe, Anonymous Web Searching... ditch Google.
Try the Search Engine with the Funny Name -
[DuckDuckGo.com](https://duckduckgo.com/)
"The Search Engine That Doesn't Track You"***
***Visitors Since We Went Online***
---
***Powered By
&***
|
| http://www.RobotsAndComputers.com/robots/index.htm |
<HTML>
<HEAD><TITLE>Anatomy of a Pipe</TITLE>
<META Name="author" Content="Chet Gottfried">
<META Name="description" Content="The anatomy of a (cutaway) briar pipe, showing its key features.">
<META Name="keywords" Content="pipe, pipes, pipe maker, pipe designer">
</HEAD>
<BODY BACKGROUND="images/p96-long.jpg" BGCOLOR=0 TEXT="#FFFBF0" LINK="#ABC7E9" VLINK="#9CD8F1" alink="#ABC7E9">
<FONT SIZE=+2 COLOR=#CBA6D0><B>The anatomy of a pipe</B></FONT>
<br> <p>
<hr width=600 size=3 noshade align=left>
<br> <br>
<TABLE BORDER=0 WIDTH=580 HEIGHT=0 CELLPADDING=0 CELLSPACING=0>
<TR><TD width=220 valign=top> <br></td><td width=360>
No matter how typical or atypical, all pipes share certain features, as shown below.<br> <br>
</td></tr>
<tr><td colspan=2 align=right>
<TABLE BORDER=5 WIDTH=465 HEIGHT=0 CELLPADDING=0 CELLSPACING=0>
<td>
<a href="../3d/3d12.htm" onMouseOver="window.status='Have a look at the whole pipe'; return true"
onMouseOut="window.status=''; return true"><IMG SRC="images/pipe-cut.jpg" ALT="Cutaway of a pipe" WIDTH=465 HEIGHT=280 ALIGN=middle border=0></a>
</td></table>
</td></tr><tr><td width=220> <br></td><td width=360>
<br> <br>
<font face="arial,helvetica" color="white"><b>Tobacco chamber <i>or</i> cavity</b></font><br>
The portion of the pipe in which tobacco is placed, obviously. <i>Carbonizing</i> (or blackening) the interior of the tobacco chamber supposedly lets a pipe be broken in easier, but it also serves to hide a pipe's flaws. Note that Mark's pipes are never carbonized. (The chamber is even in tone; I let a grain show in the illustration to highlight it.) The chamber may have straight sides or be conical.
<p>
<font face="arial,helvetica" color="white"><b>Shank <i>or</i> neck</b></font><br>
The connection between stem and bowl. It may be rather long or very short; some folks believe that the longer the neck, the better the smoke.
<p>
<font face="arial,helvetica" color="white"><b>Airhole</b></font><br>
The intersection of the air shaft through the shank and into the tobacco chamber. The typical preference is that the airhole should be as close to the bottom of the chamber as possible.
<p>
<font face="arial,helvetica" color="white"><b>Grain</b></font><br>
A measure of the quality of a pipe. A straight-grain pipe (that is, one in which the grain lines are even and parallel with one another) is considered to be the highest quality in terms of promising an excellent smoking pipe. (However, an interesting grain shape may hold its own fascinations.)
<p>
<font face="arial,helvetica" color="white"><b>Stem</b></font><br>
The connection between the pipe and the smoker. Generally made of vulcanite (i.e., hard rubber) or lucite, the stem is also known as the mouthpiece. Vulcanite (only in black) is softer but wears out faster; lucite comes in a variety of colors and transparencies.
</td></tr>
</table>
<br> <br>
<hr width=600 size=3 noshade align=left>
<br> <br>
<font face="arial,helvetica" size=-1><b><a href="smoke1.htm">Pipe & tobacco links</A> <p>
<a href="../index.html">Look Out Now!</a></b></font>
<P>
</BODY>
</HTML> |
Anatomy of a Pipe
**The anatomy of a pipe**
---
| | |
| --- | --- |
| |
No matter how typical or atypical, all pipes share certain features, as shown below. |
|
[Cutaway of a pipe](../3d/3d12.htm) |
|
| |
**Tobacco chamber *or* cavity**
The portion of the pipe in which tobacco is placed, obviously. *Carbonizing* (or blackening) the interior of the tobacco chamber supposedly lets a pipe be broken in easier, but it also serves to hide a pipe's flaws. Note that Mark's pipes are never carbonized. (The chamber is even in tone; I let a grain show in the illustration to highlight it.) The chamber may have straight sides or be conical.
**Shank *or* neck**
The connection between stem and bowl. It may be rather long or very short; some folks believe that the longer the neck, the better the smoke.
**Airhole**
The intersection of the air shaft through the shank and into the tobacco chamber. The typical preference is that the airhole should be as close to the bottom of the chamber as possible.
**Grain**
A measure of the quality of a pipe. A straight-grain pipe (that is, one in which the grain lines are even and parallel with one another) is considered to be the highest quality in terms of promising an excellent smoking pipe. (However, an interesting grain shape may hold its own fascinations.)
**Stem**
The connection between the pipe and the smoker. Generally made of vulcanite (i.e., hard rubber) or lucite, the stem is also known as the mouthpiece. Vulcanite (only in black) is softer but wears out faster; lucite comes in a variety of colors and transparencies.
|
---
**[Pipe & tobacco links](smoke1.htm)
[Look Out Now!](../index.html)**
| https://www.lookoutnow.com/pipe/anatomy.htm |
<HTML><HEAD>
<TITLE>The Richfiles: Walkman Page</TITLE>
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<CENTER><H1><IMG ALIGN=No SRC="RichFiles.gif" WIDTH=232 HEIGHT=166 ALT="The RichFiles"></H1></CENTER>
<P>
<CENTER><H2>Walkman</H2></CENTER>
<P><HR><p>
<center><IMG SRC="robots/WalkmanFront.jpg" ><br>
Rebuilt Walkman. (after it walked off a table and was repaired)<p>
<IMG SRC="robots/Walkman.jpg" ><br>
Original Walkman. (before accident)
</center>
<p>
<B>Description</B>
<P>
The first robot I built is a 4 leg/2 motor walker. It uses a 4 Nv microcore (Nv stands for Nervous network). The microcore is a loop of Nv units that cycle pulses through to operate a device. Mark Tilden designed the microcore using a 74HC14 schmitt triggered inverter, a resistor, and a capacitor.<p><hr><p>
Walkman Was originally very different than it is now. The original design was large, bulky, and the two motors ended up getting stripped because the gears were too weak. I later used a motor from the eject mechanism of a camcorder and a walkman motor with a hand built gearbox. Walkman (as well as my three solar robots and BORIS, my muscle wire robot) were used on an episode of Algo's FACTory. (Sunday mornings at 9:30 on FOX, at least in my area). It's a children's educational show. Walkman accidentally walked itself off of a table and the front gearbox (the one I built) was destroyed. I replaced it and the back motor (so they matched) with high quality gear motors. They are great!!! I also added eyes just after first getting it to work. When it's dark, it "sleeps." One of the most notable features is actually the "head" made from a diffraction grating (like on those action baseball cards where you tilt it and the image changes). It's there for appearance and to act as a barrier between the eyes, (though they don't do much of anything except cause the robot to sleep).<p>
<center><IMG SRC="robots/WalkmanSide.jpg" ><br>
Side view of Walkman</center><p>
<B>Mechanics</B><P>
2 motor walkers are unique in that mechanical design is almost more important than the electronics. The robot moves by "falling" forward. It lifts it's front legs, pushes with it's back. An ideal 2 motor walker should have it's center of gravity as close to the point where two imaginary lines would cross if each line attached to the feet of the legs diagonally apart. To tell if a 2 motor walker has a proper center of gravity, tilt the front legs and see if it can tip from front to back. If it stays where you tip it, it's pretty good. The front legs should be tipped up at approximately 30 degrees. The legs shapes you need to play with. Try different things. If you use servos, you can get a 4 point horn and bend the legs into a triangle shape at the center. attach the points to three of the points on the horn. The 4th point can have a spring attached to bias and help center the legs, or to operate stop switches. The servo's built in potentiometer can be used to bias a microcore or if you use a micro controller, the servo does not need modification.<br>
Two motor walkers can't really turn efficiently. you can bias the rear legs to make it turn a wide radius, but it's really not too feasible for a beginner. I may refit my walker to do it or do another 2 motor walker. I do plan on another 2 motor walker using off the shelf parts. The instructions will be found on the main robotics page.<p>
<B>Electronics</B><P>
<B>The Nervous Network:</B> My 2 motor walker uses a nervous network. Nervous networks are very similar to Neural networks, however there are important differences. Nervous networks, in the most basic sense, imitate neurons that are responsible for reflexes. Each neuron is a single inverter. The inverter MUST have a schmitt trigger. A schmitt trigger allows a signal to fluctuate a little bit without rapid triggering of the output. There are two thresholds, a high and a low. if the input is low and rises, the output won't go low until the input hit's the high threshold. if the input goes back below the high threshold, the output won't change, but if it goes far low to the low threshold, then the output will go back to high. This allows leeway for the input. It's a very interesting system
<p>
The 74HC14 hex schmitt inverter is the most popular inverter for use in nervous networks. They can be chained, or looped. A loop of nervous networks are called a microcore. the inverters are joined by a capacitor, usually between .1µf and .3µf (I like using .22µf capacitors). A resistor is attached to the inputs. 1 Mega Ohm (M½) is a good value to use with .22µf capacitors. It's easier to alter the value of the resistors than the caps. You can also use the servo pots to bias the microcore. attach the two outside pins to the inputs of the neurons that drive that servo. Attach the center lead through a resistor to adjust the value properly, and then it to ground. if you attach the microcore straight with fixed resistors, than a fixed resistor on the inputs and to ground. The outputs of the microcore can go to LEDs, drivers, or other devices. <p>
The "odd" microcore I accidentally built. It's a mistake in my PCB, but it works:
<CENTER><IMG SRC="robots/4NvOddCoreSchem.gif"><br>
Schematic of the odd 4Nv microcore (note the place the output attaches to)<p>
<IMG SRC="robots/4NvOddcore.gif"><br>
PCB layout of the odd 4Nv microcore (note the place the output attaches to)<p>
The following is a traditional microcore:<br>
<IMG SRC="robots/4NvMicrocoreSchem.gif"><br>
Schematic of the traditional 4Nv microcore<p>
<IMG SRC="robots/4NvMicrocore.gif"><br>
PCB layout of the traditional 4Nv microcore</CENTER><p>
The Nervous network and Microcore are patented my Mark Tilden. It's a really interesting device. It has many uses! <p>
<center><IMG SRC="robots/WalkmanRear.jpg" ><br>
Rear view of Walkman</center>
<p>
<B>The Motor drivers:</B> I used an H-Bridge to drive the motors on this particular robot. The H-Bridge is a rather ingenious design. I don't know who invented it, but it's an EXCELLENT design. It uses 4 transistors to route electricity through a motor. There are two inputs. One attaches to one pair of transistors and the other to the other pair. The schematic resembles an "H" (hence the name). When both are on or both off, the transistor with the polarity matching the input activates. In this case, it's equivalent to connecting both wires of the motor to (+) or (-) on the battery. It won't work. If one OR the other , but NOT both, are on, then one side of the motor is routed to (+) or to (-) and the other side remains at it's former polarity. This creates a (+) on one side and a (-) on the other, or vise versa, depending on which line is active. This makes the motor turn one way or the other. By attaching the microcore or a micro controller to the inputs, you can control a motor. This requires a DC motor, which can be a hacked servo. remove the electronics, but leave the pot and motor (some servos use the pot as the axle for the main gear (one I had did anyway). Attach the driver outputs straight to the motor and the pot can be attached to the microcore (optionally).<p>
<p>
<CENTER><IMG SRC="robots/HBridge4Schem.gif"><br>
Schematic of the dual 4 transistor H-Bridge<p>
<IMG SRC="robots/DualHBridge4.gif"><br>
PCB layout of the dual 4 transistor H-Bridge</CENTER>
<p>
<B>Walking</B><P>
The microcore is attached to the H-Bridge driver. There are four neurons, and 2 motors (a neuron for each direction the motors can turn). The sequence I use is as follows:<p>
Front Clockwise, Rear Counter Clockwise, Front Counter Clockwise, and Rear Clockwise<p>
The front leg lifts, the rear leg pushes forward, the front legs shift balance and fall forward and the rear legs push again. It continues this in a loop and creates forward motion. To reverse, you can reverse the rear motor, however this robot does not have that feature.<p>
That's pretty much everything I've got on my first robot, Walkman. I've not included instructions for building it, since there are lots of custom and limited quantity parts. It can be built by using servos or ither motors. Just make sure the front motor is at approximately a 30 degree angle.
<p>
For a video of Walkman, you can check out this Quicktime video. It's a nice side view of Walkman walking, as viewed by another robot with a camera mounted on it's side. It follows Walkman next to it, slightly slower, so you see Walkman walking accross the screen, but you get more footage cause the cambot follows it. Cambot is just a plastic Robotix kit that I threw together. Next thing you know, I'll probably start setting up a model trains with the camera to follow it in panoramic views! :)
<p><A HREF="http://richfiles.solarbotics.net/video/Walkman.mov" TARGET="WalkmanJrVideoWindow">Walkman.mov Video-4834 K</A>
<p><A HREF="http://richfiles.solarbotics.net/video/WalkmanPhotopopper.mov" TARGET="WalkmanPhotopopperVideoWindow">Walkman & Photopopper Video-253 K</A>
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The Richfiles: Walkman Page
# The RichFiles
## Walkman
---
![](robots/WalkmanFront.jpg)
Rebuilt Walkman. (after it walked off a table and was repaired)
![](robots/Walkman.jpg)
Original Walkman. (before accident)
**Description**
The first robot I built is a 4 leg/2 motor walker. It uses a 4 Nv microcore (Nv stands for Nervous network). The microcore is a loop of Nv units that cycle pulses through to operate a device. Mark Tilden designed the microcore using a 74HC14 schmitt triggered inverter, a resistor, and a capacitor.
---
Walkman Was originally very different than it is now. The original design was large, bulky, and the two motors ended up getting stripped because the gears were too weak. I later used a motor from the eject mechanism of a camcorder and a walkman motor with a hand built gearbox. Walkman (as well as my three solar robots and BORIS, my muscle wire robot) were used on an episode of Algo's FACTory. (Sunday mornings at 9:30 on FOX, at least in my area). It's a children's educational show. Walkman accidentally walked itself off of a table and the front gearbox (the one I built) was destroyed. I replaced it and the back motor (so they matched) with high quality gear motors. They are great!!! I also added eyes just after first getting it to work. When it's dark, it "sleeps." One of the most notable features is actually the "head" made from a diffraction grating (like on those action baseball cards where you tilt it and the image changes). It's there for appearance and to act as a barrier between the eyes, (though they don't do much of anything except cause the robot to sleep).
![](robots/WalkmanSide.jpg)
Side view of Walkman
**Mechanics**
2 motor walkers are unique in that mechanical design is almost more important than the electronics. The robot moves by "falling" forward. It lifts it's front legs, pushes with it's back. An ideal 2 motor walker should have it's center of gravity as close to the point where two imaginary lines would cross if each line attached to the feet of the legs diagonally apart. To tell if a 2 motor walker has a proper center of gravity, tilt the front legs and see if it can tip from front to back. If it stays where you tip it, it's pretty good. The front legs should be tipped up at approximately 30 degrees. The legs shapes you need to play with. Try different things. If you use servos, you can get a 4 point horn and bend the legs into a triangle shape at the center. attach the points to three of the points on the horn. The 4th point can have a spring attached to bias and help center the legs, or to operate stop switches. The servo's built in potentiometer can be used to bias a microcore or if you use a micro controller, the servo does not need modification.
Two motor walkers can't really turn efficiently. you can bias the rear legs to make it turn a wide radius, but it's really not too feasible for a beginner. I may refit my walker to do it or do another 2 motor walker. I do plan on another 2 motor walker using off the shelf parts. The instructions will be found on the main robotics page.
**Electronics**
**The Nervous Network:** My 2 motor walker uses a nervous network. Nervous networks are very similar to Neural networks, however there are important differences. Nervous networks, in the most basic sense, imitate neurons that are responsible for reflexes. Each neuron is a single inverter. The inverter MUST have a schmitt trigger. A schmitt trigger allows a signal to fluctuate a little bit without rapid triggering of the output. There are two thresholds, a high and a low. if the input is low and rises, the output won't go low until the input hit's the high threshold. if the input goes back below the high threshold, the output won't change, but if it goes far low to the low threshold, then the output will go back to high. This allows leeway for the input. It's a very interesting system
The 74HC14 hex schmitt inverter is the most popular inverter for use in nervous networks. They can be chained, or looped. A loop of nervous networks are called a microcore. the inverters are joined by a capacitor, usually between .1µf and .3µf (I like using .22µf capacitors). A resistor is attached to the inputs. 1 Mega Ohm (M½) is a good value to use with .22µf capacitors. It's easier to alter the value of the resistors than the caps. You can also use the servo pots to bias the microcore. attach the two outside pins to the inputs of the neurons that drive that servo. Attach the center lead through a resistor to adjust the value properly, and then it to ground. if you attach the microcore straight with fixed resistors, than a fixed resistor on the inputs and to ground. The outputs of the microcore can go to LEDs, drivers, or other devices.
The "odd" microcore I accidentally built. It's a mistake in my PCB, but it works:
![](robots/4NvOddCoreSchem.gif)
Schematic of the odd 4Nv microcore (note the place the output attaches to)
![](robots/4NvOddcore.gif)
PCB layout of the odd 4Nv microcore (note the place the output attaches to)
The following is a traditional microcore:
![](robots/4NvMicrocoreSchem.gif)
Schematic of the traditional 4Nv microcore
![](robots/4NvMicrocore.gif)
PCB layout of the traditional 4Nv microcore
The Nervous network and Microcore are patented my Mark Tilden. It's a really interesting device. It has many uses!
![](robots/WalkmanRear.jpg)
Rear view of Walkman
**The Motor drivers:** I used an H-Bridge to drive the motors on this particular robot. The H-Bridge is a rather ingenious design. I don't know who invented it, but it's an EXCELLENT design. It uses 4 transistors to route electricity through a motor. There are two inputs. One attaches to one pair of transistors and the other to the other pair. The schematic resembles an "H" (hence the name). When both are on or both off, the transistor with the polarity matching the input activates. In this case, it's equivalent to connecting both wires of the motor to (+) or (-) on the battery. It won't work. If one OR the other , but NOT both, are on, then one side of the motor is routed to (+) or to (-) and the other side remains at it's former polarity. This creates a (+) on one side and a (-) on the other, or vise versa, depending on which line is active. This makes the motor turn one way or the other. By attaching the microcore or a micro controller to the inputs, you can control a motor. This requires a DC motor, which can be a hacked servo. remove the electronics, but leave the pot and motor (some servos use the pot as the axle for the main gear (one I had did anyway). Attach the driver outputs straight to the motor and the pot can be attached to the microcore (optionally).
![](robots/HBridge4Schem.gif)
Schematic of the dual 4 transistor H-Bridge
![](robots/DualHBridge4.gif)
PCB layout of the dual 4 transistor H-Bridge
**Walking**
The microcore is attached to the H-Bridge driver. There are four neurons, and 2 motors (a neuron for each direction the motors can turn). The sequence I use is as follows:
Front Clockwise, Rear Counter Clockwise, Front Counter Clockwise, and Rear Clockwise
The front leg lifts, the rear leg pushes forward, the front legs shift balance and fall forward and the rear legs push again. It continues this in a loop and creates forward motion. To reverse, you can reverse the rear motor, however this robot does not have that feature.
That's pretty much everything I've got on my first robot, Walkman. I've not included instructions for building it, since there are lots of custom and limited quantity parts. It can be built by using servos or ither motors. Just make sure the front motor is at approximately a 30 degree angle.
For a video of Walkman, you can check out this Quicktime video. It's a nice side view of Walkman walking, as viewed by another robot with a camera mounted on it's side. It follows Walkman next to it, slightly slower, so you see Walkman walking accross the screen, but you get more footage cause the cambot follows it. Cambot is just a plastic Robotix kit that I threw together. Next thing you know, I'll probably start setting up a model trains with the camera to follow it in panoramic views! :)
[Walkman.mov Video-4834 K](http://richfiles.solarbotics.net/video/Walkman.mov)
[Walkman & Photopopper Video-253 K](http://richfiles.solarbotics.net/video/WalkmanPhotopopper.mov)
---
[Return to the Robotics Page](RobotTopics.html)
---
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<!DOCTYPE html>
<html>
<head>
<meta charset="UTF-8">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<title>Cool Awesome MARS FACTS!</title>
<link href="/style.css" rel="stylesheet" type="text/css" media="all">
</head>
<body>
<h1> <center> welcome to this awesome website where you will learn alot of things about mars! </center> </h1>
<center> <p>Hello! today i am going to be talking about cool mars facts! Did you know that Mars is Neighbors with Earth? yes! Mars is the 4th Planet away from the sun. Also, if you didn't know, mars's Nickname is "The Red Planet </p> </center>
<center> <p> In 1610, Galileo Galilei Discovered Mars through a Telescope. Did you know that Mars is 4.603 BILLION years old? ? That's true! and people started Studying Mars in the Late 1940s.</p> </center>
<center> <p> For earth, it takes about 687 Days for mars to revolve around the sun. When mars rotates, it rotates counterclockwise. When mars is measured, it has the diameter of 4,212.3 mi, and the earth's diameter is bigger.</p> </center>
<center> <p> Mars's mass is 6.39 x 10^23 kg. The planet is mostly made of silicon dioxide and looks like a rocky, red planet, and the rocks are made out of iron.</p> </center>
<center> <p> Mars's temputure average at about -81 degrees, but in the winter it is about -220 degrees. that is COLD! </p> </center>
<center> <p> Did you know that Mars is named after the god of war? one of mars's moons is in danger. Mars had water, but a long time ago it froze and is now frozen.</p> </center> <center> <p> i hope you liked this website about mars facts and make sure to check out the other planets!</p> </center>
<center> <img src="/Neocities.jpeg"> </center>
<center> <img src="/Mars1.jpeg"> </center>
<center> <img src="MarsSpin.gif"> </center>
<img src="11.gif">
<img src="33.gif">
<center> <p>To learn more, check out <a href="https://mars.nasa.gov/all-about-mars/facts/">This Website</a>!</p> </center>
</body>
</html> |
Cool Awesome MARS FACTS!
# welcome to this awesome website where you will learn alot of things about mars!
Hello! today i am going to be talking about cool mars facts! Did you know that Mars is Neighbors with Earth? yes! Mars is the 4th Planet away from the sun. Also, if you didn't know, mars's Nickname is "The Red Planet
In 1610, Galileo Galilei Discovered Mars through a Telescope. Did you know that Mars is 4.603 BILLION years old? ? That's true! and people started Studying Mars in the Late 1940s.
For earth, it takes about 687 Days for mars to revolve around the sun. When mars rotates, it rotates counterclockwise. When mars is measured, it has the diameter of 4,212.3 mi, and the earth's diameter is bigger.
Mars's mass is 6.39 x 10^23 kg. The planet is mostly made of silicon dioxide and looks like a rocky, red planet, and the rocks are made out of iron.
Mars's temputure average at about -81 degrees, but in the winter it is about -220 degrees. that is COLD!
Did you know that Mars is named after the god of war? one of mars's moons is in danger. Mars had water, but a long time ago it froze and is now frozen.
i hope you liked this website about mars facts and make sure to check out the other planets!
![](/Neocities.jpeg)
![](/Mars1.jpeg)
![](MarsSpin.gif)
![](11.gif)
![](33.gif)
To learn more, check out [This Website](https://mars.nasa.gov/all-about-mars/facts/)!
| https://marsfacts.neocities.org/ |
<!doctype html public "-//IETF//DTD HTML//EN">
<HTML>
<HEAD>
<TITLE>"Fundamentals of Freemasonry" by Norman Williams Crabbe
</TITLE>
<META NAME="GENERATOR" CONTENT="Internet Assistant for Word 1.0Z">
<META NAME="AUTHOR" CONTENT="William Dougherty">
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<BODY>
<H3>Fundamentals of Freemasonry</H3>
<H5>By Norman Williams Crabbe, MPS</H5>
<P>
Freemasonry uses allegorical symbols to teach a philosophy concerning
the nature of the Creator, the origins of the universe, and humanity's
universal destiny. The religious doctrines in which most people
are raised are designed to satisfy the basic needs of the general
population. To get a truer understanding of the nature of Deity
requires a long-term commitment of study. The Freemasonic initiate
is put on the path of this study by being initiated into the fraternity
of Masonry, a Westernized religious Mystery school. If the initiate
studies the ritual, he will receive, proportionate to his ability
to understand, deep mystic revelations regarding the nature of
the universe and our mystic journey through it. Freemasonry keeps
alive this knowledge from generation to generation until such
time as it is understood and accepted by all beings.
<P>
Though dealing exclusively with religious themes, Freemasonry
is not a religion: no one dogma is professed as being particularly
Masonic. Nor is the Masonic Lodge a place of worship; it would
be better considered a classroom. Freemasonry "teaches"
an occult philosophy to lead the initiate towards the essence
of religious thought. All that is required of the initiate is
an expressed belief in higher intelligence (God); therefore, no
atheist can become a Mason. Religions in and of themselves are
made by mankind to explain Deity. Freemasons come in all colors
and nationalities and may worship Jehovah, Jesus, Mohammed, or
Krishna, to name a few.
<P>
Masons themselves cannot agree on exactly when Freemasonry began.
Some say it was when the Grand Lodge of England was established
in 1717. Others who have studied the fraternity closely put the
date nearer to 5000 BC -- though it was not then necessarily called
Freemasonry -- with major modifications around the first century
AD.
<P>
Blue Lodge Freemasonry and its "higher" bodies, the
York and Scottish Rite, are a tool that teaches a view of life
that for centuries has been on the cutting edge of religious and
secular thought. Freemasonic ritual is secret because men throughout
history have persecuted their fellows for having opinions different
from accepted doctrine; secrecy protects life, limb, and the message.
Most Freemasons, however, do not understand the allegorical, mystic
significance in the ritual work. For them it is a fraternal club
with a secret ritualistic initiation which meets once or twice
a month for fellowship and to sponsor charities.
<P>
There are three degrees in Freemasonry. The first is the Entered
Apprentice Degree, a purification or a birth into Freemasonry.
The Fellow Craft Degree represents the learning years or, symbolically,
manhood. The Master Mason Degree is a symbolic death as one man
(H.A.) and resurrection and reincarnation into a more perfect
life as a Master Mason, an adept in the art of life, a man with
the secret knowledge, a Gnostic. Progressing through the three
degrees of Masonry, the student increases in Masonic knowledge.
When the student "knows" the next step, he is passed
and then "raised" up as a Master Mason. He is then informed
that one of the most important duties of a Master Mason is to
"seek truth."
<P>
The major posts in a Lodge all have allegorical significance.
For example, the Master of the Lodge symbolizes King Solomon or
Deity, heaven, maleness, aggressiveness, or the sun which controls
life. The Junior Warden symbolizes the space half way between
the sun and moon, and controls the refreshment at High Twelve
and, because of his position at meridian, can better control the
time for the Worshipful Master and the Senior Warden. The Junior
Warden is the fulcrum or the balancer of the day. The Senior Warden
symbolizes the opposite part of the Divine Triad: the Moon, Mother
Earth, mother, femaleness, and passiveness, and creates the balance
needed to run the lodge by representing the other half of the
daily and yearly cycle: night.
<P>
The Masonic signs and tools also have esoteric, allegorical meanings.
Let's look at some of the Masonic symbols as they apply to harmony.
The level symbolizes balance by reminding us to be level in our
actions. The plumb symbolizes balance by informing us to walk
upright as citizens and be straight and upright in our actions.
The square symbolizes virtue or morality, the balance of good
and evil in our lives. The compasses symbolize morality controlled
by containing good and evil within the cycle of our outward bodily
manifestation. The apron symbolizes innocence or morality by covering
the passionate parts of man -- again, keeping good and evil in
due bounds. The 24-inch gauge or ruler symbolizes the balancing
act Masons must achieve for a fruitful life by dividing the daily
twenty-four hours into eight hours of work, eight hours of divine
contemplation, and eight hours of rest from the other sixteen
hours of human and divine toil.
<P>
<IMG SRC="s8onnwc.gif" ALIGN="BOTTOM">
<P>
The book of holy law symbolizes the Rule of the Masonic Order.
And, as the Knights Templar of old, Masons also have a rule from
which to work: the Sacred Book of Law, the Holy Bible, the Koran,
the Upanishads, and so on. For, in fact, Freemasons are self-ordained
holy men, and true holy men seek harmony and balance in the universe.
<P>
The four prime beliefs of Freemasonry are: the Fatherhood of God;
the brotherhood of man; relief to others; and the search for truth.
First and foremost, Freemasonry is a philosophy based on the position
that there is a Supreme Being and that all human beings are of
the same family. All men are created equal in the eyes of the
Supreme Being. Whether white, black, Christian, Jew, Muslim, European,
African, or Asian, we are all brothers. The duty of a Freemason
is to practice brotherly love and friendship by transcending the
differences in people to find their similarities. While in a Masonic
Lodge anywhere in the world, a Brother Master Mason cannot discuss
politics or religion, in order that first and foremost there is
harmony among the Brethren while in the lodge.
<P>
Relief, the third prime belief, means that Freemasons are obligated
to help others less fortunate than themselves when it is possible
to do so. Charity work, whether of the group or individuals, is
most important.
<P>
The search for truth, the last fundamental principle, is a Masonic
mainstay. In all worldly endeavors Masons are reminded to be truthful
to others, to follow the path of truth, and ever to look for the
truth in their daily lives. As one's knowledge grows, the search
becomes easier. Freemasonry leads toward truth by giving the student
"working tools" to find true answers. As one grows in
the study of Freemasonry, one also grows in the knowledge of all
religions. Within all ancient religions the student will discover
<EM>gnosis</EM>: knowledge or fundamental true principles. Truth
is learned. From true knowledge, wisdom is born. To be wise is
to be godly, and to be godly is to know ourselves, our universe,
and our Creator.
<P>
Practicing the four Masonic beliefs outside the lodge instills
harmony into everyday life. When enough Masons throughout the
world practice the four fundamental beliefs toward their fellowmen,
they will be passing along the true code of ethics for the earth.
Hopefully, by this example others will move towards the ideal
of practiced harmony and treat their fellowmen with peace, love,
tolerance, and understanding, and this worldly peace will in turn
improve the harmony of the universe.
<P>
Masonic ritual, if examined closely, transcends Christian and
Jewish thought and is inclusive of all religions, past and present,
that hold to the theory of a Living God and man's divine spirit
having the ability to "bind back" to his Creator. If
we look at Freemasonry in this light, we should be able, by careful
study, to realize our divine mission while in human form.
<P>
If Freemasonry does nothing else, it will continue to shape world
events by bringing together men of different races, creeds, and
nationalities under the auspices of the Masonic teachings of brotherly
love, friendship, relief, and truth. In this one act, it will
have served mankind on a grand scale by promoting a dialogue among
all members of the human race.
<DIR>
<LI>(From Sunrise magazine, October/November 1998. Copyright ©
1998 by Theosophical University Press.)
</DIR>
<HR>
<P>
<A HREF="../general/rel-selc.htm">World Spiritual Traditions Menu</A>
</BODY>
</HTML>
|
"Fundamentals of Freemasonry" by Norman Williams Crabbe
### Fundamentals of Freemasonry
##### By Norman Williams Crabbe, MPS
Freemasonry uses allegorical symbols to teach a philosophy concerning
the nature of the Creator, the origins of the universe, and humanity's
universal destiny. The religious doctrines in which most people
are raised are designed to satisfy the basic needs of the general
population. To get a truer understanding of the nature of Deity
requires a long-term commitment of study. The Freemasonic initiate
is put on the path of this study by being initiated into the fraternity
of Masonry, a Westernized religious Mystery school. If the initiate
studies the ritual, he will receive, proportionate to his ability
to understand, deep mystic revelations regarding the nature of
the universe and our mystic journey through it. Freemasonry keeps
alive this knowledge from generation to generation until such
time as it is understood and accepted by all beings.
Though dealing exclusively with religious themes, Freemasonry
is not a religion: no one dogma is professed as being particularly
Masonic. Nor is the Masonic Lodge a place of worship; it would
be better considered a classroom. Freemasonry "teaches"
an occult philosophy to lead the initiate towards the essence
of religious thought. All that is required of the initiate is
an expressed belief in higher intelligence (God); therefore, no
atheist can become a Mason. Religions in and of themselves are
made by mankind to explain Deity. Freemasons come in all colors
and nationalities and may worship Jehovah, Jesus, Mohammed, or
Krishna, to name a few.
Masons themselves cannot agree on exactly when Freemasonry began.
Some say it was when the Grand Lodge of England was established
in 1717. Others who have studied the fraternity closely put the
date nearer to 5000 BC -- though it was not then necessarily called
Freemasonry -- with major modifications around the first century
AD.
Blue Lodge Freemasonry and its "higher" bodies, the
York and Scottish Rite, are a tool that teaches a view of life
that for centuries has been on the cutting edge of religious and
secular thought. Freemasonic ritual is secret because men throughout
history have persecuted their fellows for having opinions different
from accepted doctrine; secrecy protects life, limb, and the message.
Most Freemasons, however, do not understand the allegorical, mystic
significance in the ritual work. For them it is a fraternal club
with a secret ritualistic initiation which meets once or twice
a month for fellowship and to sponsor charities.
There are three degrees in Freemasonry. The first is the Entered
Apprentice Degree, a purification or a birth into Freemasonry.
The Fellow Craft Degree represents the learning years or, symbolically,
manhood. The Master Mason Degree is a symbolic death as one man
(H.A.) and resurrection and reincarnation into a more perfect
life as a Master Mason, an adept in the art of life, a man with
the secret knowledge, a Gnostic. Progressing through the three
degrees of Masonry, the student increases in Masonic knowledge.
When the student "knows" the next step, he is passed
and then "raised" up as a Master Mason. He is then informed
that one of the most important duties of a Master Mason is to
"seek truth."
The major posts in a Lodge all have allegorical significance.
For example, the Master of the Lodge symbolizes King Solomon or
Deity, heaven, maleness, aggressiveness, or the sun which controls
life. The Junior Warden symbolizes the space half way between
the sun and moon, and controls the refreshment at High Twelve
and, because of his position at meridian, can better control the
time for the Worshipful Master and the Senior Warden. The Junior
Warden is the fulcrum or the balancer of the day. The Senior Warden
symbolizes the opposite part of the Divine Triad: the Moon, Mother
Earth, mother, femaleness, and passiveness, and creates the balance
needed to run the lodge by representing the other half of the
daily and yearly cycle: night.
The Masonic signs and tools also have esoteric, allegorical meanings.
Let's look at some of the Masonic symbols as they apply to harmony.
The level symbolizes balance by reminding us to be level in our
actions. The plumb symbolizes balance by informing us to walk
upright as citizens and be straight and upright in our actions.
The square symbolizes virtue or morality, the balance of good
and evil in our lives. The compasses symbolize morality controlled
by containing good and evil within the cycle of our outward bodily
manifestation. The apron symbolizes innocence or morality by covering
the passionate parts of man -- again, keeping good and evil in
due bounds. The 24-inch gauge or ruler symbolizes the balancing
act Masons must achieve for a fruitful life by dividing the daily
twenty-four hours into eight hours of work, eight hours of divine
contemplation, and eight hours of rest from the other sixteen
hours of human and divine toil.
![](s8onnwc.gif)
The book of holy law symbolizes the Rule of the Masonic Order.
And, as the Knights Templar of old, Masons also have a rule from
which to work: the Sacred Book of Law, the Holy Bible, the Koran,
the Upanishads, and so on. For, in fact, Freemasons are self-ordained
holy men, and true holy men seek harmony and balance in the universe.
The four prime beliefs of Freemasonry are: the Fatherhood of God;
the brotherhood of man; relief to others; and the search for truth.
First and foremost, Freemasonry is a philosophy based on the position
that there is a Supreme Being and that all human beings are of
the same family. All men are created equal in the eyes of the
Supreme Being. Whether white, black, Christian, Jew, Muslim, European,
African, or Asian, we are all brothers. The duty of a Freemason
is to practice brotherly love and friendship by transcending the
differences in people to find their similarities. While in a Masonic
Lodge anywhere in the world, a Brother Master Mason cannot discuss
politics or religion, in order that first and foremost there is
harmony among the Brethren while in the lodge.
Relief, the third prime belief, means that Freemasons are obligated
to help others less fortunate than themselves when it is possible
to do so. Charity work, whether of the group or individuals, is
most important.
The search for truth, the last fundamental principle, is a Masonic
mainstay. In all worldly endeavors Masons are reminded to be truthful
to others, to follow the path of truth, and ever to look for the
truth in their daily lives. As one's knowledge grows, the search
becomes easier. Freemasonry leads toward truth by giving the student
"working tools" to find true answers. As one grows in
the study of Freemasonry, one also grows in the knowledge of all
religions. Within all ancient religions the student will discover
*gnosis*: knowledge or fundamental true principles. Truth
is learned. From true knowledge, wisdom is born. To be wise is
to be godly, and to be godly is to know ourselves, our universe,
and our Creator.
Practicing the four Masonic beliefs outside the lodge instills
harmony into everyday life. When enough Masons throughout the
world practice the four fundamental beliefs toward their fellowmen,
they will be passing along the true code of ethics for the earth.
Hopefully, by this example others will move towards the ideal
of practiced harmony and treat their fellowmen with peace, love,
tolerance, and understanding, and this worldly peace will in turn
improve the harmony of the universe.
Masonic ritual, if examined closely, transcends Christian and
Jewish thought and is inclusive of all religions, past and present,
that hold to the theory of a Living God and man's divine spirit
having the ability to "bind back" to his Creator. If
we look at Freemasonry in this light, we should be able, by careful
study, to realize our divine mission while in human form.
If Freemasonry does nothing else, it will continue to shape world
events by bringing together men of different races, creeds, and
nationalities under the auspices of the Masonic teachings of brotherly
love, friendship, relief, and truth. In this one act, it will
have served mankind on a grand scale by promoting a dialogue among
all members of the human race.
- (From Sunrise magazine, October/November 1998. Copyright ©
1998 by Theosophical University Press.)
---
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<h1>Ice Chewers Bulletin Board - All about Chewing Ice</h1>
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<html>
<head>
<title>♥BALL WITH FEET♥</title>
</head>
<body background="BallPics/lolopastoral.png">
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<center><table border=1 cellspacing = 1 cellpadding = 10 width = 600px>
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<font color="#66066" size="6" face="verdana"><tt><b><i><u>BALL WITH FEET - A TRIBUTE</u></i></b></tt></font></center>
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<center><img src="BallPics/lolo.png"></center>
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<b>INTRODUCTION:</B><br><br>
Videogames as mass cultural form busily scavenge all the cabinets of mankind. In the process they find rare trinkets and horrible debris, old fads and styles, cultural terrors and unarticulateable desires and night bogeys. Rarefied mystic symbols are placed next to "meat" and "coin" as things for your guy to rove around and eat. In the process new structures of meaning and value emerge, haunted by figures both familiar and strange. Among them is a ball with feet.<br><br>
On this webpage I propose to explore the various manifestations of a dream: that of some form of cute ball who walks around on little feet. Definitions and technical specifics are listed below this very provisional and personal catalog.
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<center><img src="BallPics/ballscore.png"></center>
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<br><center><img src="BallPics/zelda.png"></center><br>
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<b>A LINK TO THE PAST:</b><br><br>
This game, the "AAA" of its day, represented a bold effort at shaping the traditionally bizarre iconography and sense of place in the zelda games into some kind of coherent whole. The abstract plains and rock formations of the first game were successfully converted into pieces of high fantasy. But as if in a dream the repressed videogamey bits and pieces eventually make their disguised return, in the form of a shadowy mirror realm, a "dark world" that travesties the main kingdom by filling it up again with all the goofy nonsense stuff it had initially discarded. Illegible gremlin people, rock structures, insect skeletons, ruins, off-brand videogame protagonists (Link briefly turns into a bunny!) - and in this familiar world, one of the first things we encounter is a beautiful little ball with feet, waddling forth as if to welcome us home.<br><br>
The ball in this game is called "BULLY'S FRIEND" and tells us that "I was always changing my mind, so I turned into a ball." If only it were that simple!! He is constantly pursued and bounced around by a kind of dinosaur guy, but does not refer to this in his dialog, and the goofy "boing" sounds and constant expression(?) of happy delight lead us to question whether he actually feels any kind of discomfort from this. Maybe it's a consensual relationship? Either way he seems pretty happy to run around the mountaintop forever. I wish him well in pursuing his desires.
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<center><table border=1 cellspacing = 1 cellpadding = 10 width = 800px>
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<br><center><img src="BallPics/lolo2_cover.png"><img src="BallPics/lolo2.png"></center><br>
<font color="#66066" size="3" face="verdana"><tt>
<b>ADVENTURES OF LOLO:</b><br><br>
Perhaps the paragon of orthodox ball with feet imagery in videogames - - perhaps the paragon of videogame characters in general? Staring eyes, expressionless face, gloves, sneakers, a name which is just the same short syllable repeated twice and ending in "-o", Lolo has it all! A ball with feet is all he is, and all he is content to be. Truly, he has much to teach us. <br>
But the fact that Lolo is situated so firmly and explicitly inside of this tradition also incidentally casts light on some lesser known aspects of it. For example, we also find a rare example of a "girl ball" in the person of Lolo's girlfriend, Lala, who is indistinguishable from him except that she is pink and wears a large ribbon. Secondly, delving into the franchise's origins as the "Eggerland" series for MSX turns up this powerful image:<br><br>
<center><img src="BallPics/eggerland.jpg"></center><br><br>
Here we see that Lolo is in fact covered with hair! Imagine the possibilities! That the contemporary videogame industry should take detailed hair rendering technology as the definining measure of success, while failing to turn to so obvious an application, seems to me an injustice bordering on a crime.
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<br><center><img src="BallPics/doordoor1.png"><img src="BallPics/doordoor2.gif"></center><br>
<font color="#66066" size="3" face="verdana"><tt>
<b>DOOR-DOOR:</b><br><br>
How many aliens can you shut up? Despite the brutality of his mission, Door-Door protagonist Chun ("a small, spherical animal outfitted with a baseball cap" according to Wikipedia) is in fact very cute. This was Enix's first game, based on a contest submission, which raises interesting questions - was Chun's design a deliberate attempt to echo established successes such as Q-Bert and Pac-Man, in an effort to break into the industry? Is this evidence of a kind of background consensus over what a videogame character "should be" at the time? The egg shape says Im cute, while the sassy cap says, watch out.
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<br><center><img src="BallPics/americandream.jpg"></center><br>
<font color="#66066" size="3" face="verdana"><tt>
<b>AMERICAN DREAM:</b><br><br>
One affordance of the ball with feet shape is that the generic "ball" can be replaced with more specific kinds as a simple and easy way to get something more appropriate to various thematic settings - for example a soccer ball, or a globe. In this game you play a roulette ball exploring a landscape of various casinos in search of the titular "american dream, becoming obscenely wealthy via blind submission to statistically rigged games of chance, also known as meritocracy. The dinky, ingenuous quality of the little ball also provided a frame with which to examine various sublimated anxieties about the american setting as hallucinated from 6000 miles away.<br><br>
<br><center><img src="BallPics/americandream2.png"></center><br>
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<center><table border=1 cellspacing = 1 cellpadding = 10 width = 800px>
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<br><center><img src="BallPics/finalsettennis.png"></center><br>
<font color="#66066" size="3" face="verdana"><tt>
<b>FINAL SET TENNIS:</b><br><br>
A case in point this cheerful tennis entity. In my research I am unable to determine whether he appears at any other point of the game than in the credits, possibly operating upon the same principles as pornographic mahjong variants.
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<center><table border=1 cellspacing = 1 cellpadding = 10 width = 800px>
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<br><center><img src="BallPics/mrbloopy.png"></center><br>
<font color="#66066" size="3" face="verdana"><tt>
<b>MR BLOOPY:</b><br><br>
An interesting missing link between purely gelatinous blobs like Jerry Boy and the balls with feet we all know and love. Mr Bloopy appears at first to be a highly classical form of slime blob - but he is also able to leap into the air by extruding a pseudopod shaped roughly like a human foot! Ancestor, parallel evolution or just weird?
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<center><table border=1 cellspacing = 1 cellpadding = 10 width = 800px>
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<br><center><img src="BallPics/chacknpop.png"></center><br>
<font color="#66066" size="3" face="verdana"><tt>
<b>CHACK'N POP</b><br><br>
As baby chickens are potentially the closest this world has come to producing real life balls with feet (certain frogs come close - but chickens are bipedal) it's not surprising this affordance would be seized within the industry. The New Zealand Story is another strong contender- but my personal vote goes to Chack'n Pop, as much for the name as anything. Interestingly Wikipedia does not seem to recognize it a chicken, describing Chack'n instead as "a small yellow creature (later recolored green) with extendable legs".
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<center><table border=1 cellspacing = 1 cellpadding = 10 width = 800px>
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<br><center><img src="BallPics/pommy.jpg"></center><br>
<font color="#66066" size="3" face="verdana"><tt>
<b>BOMBERMAN 64: THE SECOND ATTACK:</b><br><br>
Sufficiently cartoonish rabbitoids can also approach ball with feet status, for example in Sunsoft's Trip World. But I prefer the otherwise egregious "Pommy" animal from Bomberman 64: The Second Attack in part because of the above chart, which not only links together various kinds of ball-likes in some kind of natal stage chart but also details the precise amounts of [FRUIT] [MEAT] and [SWEETS] required for each stage.
</tt></font>
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<center><table border=1 cellspacing = 1 cellpadding = 10 width = 800px>
<tr><td bgcolor="#ffffe6">
<br><center><img src="BallPics/pacman1.jpg"><img src="BallPics/pacman2.jpg"></center><br>
<font color="#66066" size="3" face="verdana"><tt>
<b>PAC-MAN:</b><br><br>
Here is the question which has riddled all the scholars: does Pac-Man have feet? The early attempts at portraying just what Pac-Man "is" are various enough to allow for genuine doubt about this question and it's possible his legs were the addition of a later hand, like some of the heretical testaments. Eventually it became plain that all popular videogame characters have to be humanoid enough to pose for promotional drawings and possibly star in their own cartoons, and his corporate image stabilized into containing little red booties and gloves as well.<br><br>
But some of the earlier designs are still disconcerting, and we can imagine Pac-Man frantically mutating, like The Thing, emitting and discarding various forms of pseudopod and facial expression until finding some combination that fit. Maybe somewhere under there he's still just a hockey puck.
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<br><center><img src="BallPics/gimmick.jpg"></center><br>
<font color="#66066" size="3" face="verdana"><tt>
<b>GIMMICK!:</b><br><br>
Is Gimmick! a ball or just a kind of baggy plushie dinosaur thing? If we let him in, who next? The dinosaurs from Bubble Bobble? The guys from UFOuria? Hello Kitty? Can't most entities on this planet be glossed as some variety of ball, with some variety of feet? Cannot I myself...? <br><br>
Poised on the brink of a terrifying realization I am hasty to shut the door on these kinds of speculative questions. And yet Gimmick! remains inside. I believe he counts due to the size of his eyes and fact that they exist squarely in the middle of his "torso", rather than being part of a seperate "head" segment. But don't push it.
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<center><b>~~CURIOSITIES CORNER~~~</b><br><br></center>
<font color="#66066" size="3" face="verdana"><tt>
<br><center><img src="BallPics/opaopa.jpg"></center><br>
<b>FANTASY ZONE:</b><br><br>
Noted plastic spaceship and <a href="http://www.vgmuseum.com/end/arcade/c/fz28g.htm">traumatised war criminal</a> Opa-Opa has among many other delightful features the ability to sprout little feet when walking around on the ground - similar to Pop'N'TwinBee, two cute spaceship things with little sneakers and arms permanently attached. While not really a ball Opa-Opa clearly draws from something of a similar visual tradition.<br><br>
I continue to cherish the idea that someday there'll be a game about a cute cartoon car who walks around on little shoes just projecting from his undercarriage.
<br><br>
<br><center><img src="BallPics/ballz.png"></center><br>
<b>BALLZ:</b><br><br>
From Petz producers P.F. Magic comes a sort of prototype for the ball technology utilized in that game. The Ballz represent the missing link between the classic ball with feet design and strange hyerspecialized offshoots such as Vectorman.
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<br><center><img src="BallPics/coolspot.gif"></center><br>
<b>COOL SPOT:</b><br><br>
Balls with feet are oddly underrepresented in the "mascot boom" of the 1990s, possibly because it's harder to copyright a geometric primitive. A notable exception is corporate toady and stooge of Big Soda, Cool Spot, who is really more of a disc with feet maybe reflecting the fundamental cynicism of the project.... You think this is a costume, man? This is a way of LIFE!
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<br><center><img src="BallPics/eggy.png"></center><br>
<b>EGGY:</b><br><br>
A suggestive missing link between the spaceship-with-feet and ball-with-feet species, EGGY is actually a fairly sophisticated and non-cartoonish form of bipedal robot. But his goofy name and egglike structure still connect him to this lineage. Is EGGY an advanced, futuristic form of ball with feet - or is he in fact a distant ancestor, a clunky metal version of the advanced smartpolymer bioorganic entities that would come to succeed him, us, as rulers of the planet?
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<br><center><img src="BallPics/dizzy.jpg"></center><br>
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<b>DIZZY THE EGG:</b><br><br>
The popular british mascot character. I actually don't much care for Dizzy outside of his name, but it's interesting that the art for him mostly takes pains to show his limbs as sort of hovering alongside his body rather than being directly connected - shades of Ballz, but also Rayman. A possible link?
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<br><center><img src="BallPics/horacegoesskiing.png"></center><br>
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<b>HORACE GOES SKIING:</b><br><br>
Not quite a ball - or is he just a ball wearing a little smurf hat? The mystery of Horace's exact physiology is just one of his many delights. Note also the long, raggedy eyeholes, which are either eyes or just holes extending directly through his head depending on representation. Horace started as a humble pac-man clone ("Hungry Horace", 1982) but only truly blossomed when the same sprite was dropped into the context of this strangely quotidian skiing game. He appeared in many other games of different genres but was unchanging in his sprite, his mystery and his appeal.
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<center><table border=1 cellspacing = 1 cellpadding = 10 width = 800px>
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<br><center><img src="BallPics/qbert.png"></center><br>
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<b>Q-BERT:</b><br><br>
A kind of.. mysterious talking ball / muppetlike entity who lives on, or is in conflict with, a pyramid of cubes. Q-Bert's main distinguishing feature is his prominent hooverlike mouth - or nose, or possibly beak? While you may think this disqualifies him from being considered a ball proper, I think it constitutes an interesting and neglected avenue in the constant struggle to "personify" the balls somewhat. While Chun from Door-Door had his cap, and various later forms of ball would have full faces, Q-Bert's low resolution nature meant the developers had to resort to more drastic structural solutions.
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<br><center><img src="BallPics/mspacman.jpg"></center><br>
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<b>MS PAC-MAN:</b><br><br>
Not necessarily his wife - Ms Pac-Man was actually a bootleg game produced by a completely different group and then sold to the american company representing the original Namco product. While not up on my peerage I believe this makes her something more like Pac-Man's second cousin, or possibly his niece. Regardless - we know that Ms Pac-Man canonically has legs, since they are represented so prominently on the cabinet art to fairly disconcerting effect. The question of "ball with feet" vs "ball with legs" is ongoing and unsettled and will perhaps never be resolved until the final defeat of the dread god Eros. But it has to be said that all the offbrand Pac variants look better every year that the singular hegemonic Pac presence accrues yet more power for his ghoulish media empire. Bring back Pac Baby!!
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<br><center><img src="BallPics/kirby.png"></center><br>
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<b>KIRBY:</b><br><br>
YES I've seen the picture of Kirby where he has human feet and NO I don't ever want to look at it again.
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<br><center><img src="BallPics/barkley.png"></center><br>
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<b>BARKLEY, SHUT UP AND JAM: GAIDEN:</b><br><br>
A game with a wide variety of ball-related monsters. The most interesting for our purposes are the "Ball Droids", hollow metal balls with little legs and an antenna that shoots a powerful ray. For some reason I have the impression that basketballs are stored inside the ball droids to be cleaned, and that they therefore represent a sort of feral washing machine.
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<br><center><img src="BallPics/pokemon.jpg"></center><br>
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<b>POKEMON:</b><br><br>
There are now over 800 pokemon, which is a full 750 more than I can remember. Of these a substantial variety are some form of ball with feet, from Gen 1 alone we have Venonat, Jigglypuff, the Polywhirl family and likely many others. I like Jigglypuff the best for its precious little tuft.
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<br><center><img src="BallPics/digdug.jpg"></center><br>
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<b>DIG-DUG:</b><br><br>
The "Pooka", aka Deepman, is a ball with feet which has admirably adapted to subterranean additions by the simple expedient of adding some goggles. Somehow this combination works well enough for us not to question it further... Deepman lives here, he seems to fit in, he is taking adequate safety precautions. Are you?
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<br><center><img src="BallPics/milde.gif"></center><br>
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<b>YOSHI'S ISLAND:</b><br><br>
The Mario series has so many kinds of balls with feet that it would almost unbalance the list to try and put them all in - two especially notable examples being Bob-Ombs and the lovely Wanderin' Gooms from Wario Land. So I will just focus on one personal favourite.<br><br>
The "mildes" from Yoshi's Island are notable mainly for being, as their name suggests, the single least threatening enemies in the game. Even the shy guys can sometimes get you with their haphazard wandering movements - the metal, spikey walking guys resist being eaten or stepped on - various other enemies have some sort of resistance, or speciality, or form of surprise attack. The mildes' only purpose is to amble slowly forwards, and then to die. You can pop them underfoot, you can eat them for more ammo, you can shoot them with an egg if you really want to be over the top. They are comically overdestructable. And yet they have a cheery, aimless smile at all times, and seem content to just wander forwardsin this fashion. The combination of this contentness with their fragile superfluity makes them a mysterious and memorable presence.<br><br>
A milde actually becomes a boss character at one point in the game - it just keeps wandering as before, except now it's very large. Its gimmick is to split into two smaller mildes when slammed on, suggesting balls with feet reproduce by a form of cell division.
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<center><b>~~INDIE CORNER~~~</b><br><br></center></tt></font>
<br><center><img src="BallPics/bumbo.jpg"></center><br>
<font color="#66066" size="3" face="verdana"><tt>
<b>CRYPT UNDERWORLD:</b><br><br>
Once again it is the task of "indie games" to boldly reinvent an overlooked classic of form. In this case - a promotional screenshot for smash hit upcoming mall purgatory simulacrum Crypt Underworld, in which we see a mysterious yet immediately beguiling entity known only as "BUMBO", consisting entirely of billboarded ball sprites. BUMBO pushes against ball with feet orthodoxy by (1) apparently being six feet high and (2) having, instead of any kind of face, the terse but fascinating declaration.. BUMBO! The striking power that results may yet make this spirit something of a Beau Brummel figure for the next generation of balls with feet.
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<br><center><img src="BallPics/pikuniku.png"></center><br>
<b>PIKUNIKU:</b><br><br>
This ball has long legs, possibly evolved to be able to eat high pieces of foliage. A nice variant. And with physics!
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<br><center><img src="BallPics/jigglyzone.png"></center><br>
<b>JIGGLY ZONE:</b><br><br>
A collaboration between <a href="https://www.glorioustrainwrecks.com/games/*/sylvie">Sylvie</a> and <a href="http://www.hubolhubolhubol.com/">Hubol</a>, both longtime developers with a deep canon of ball-based works. Jiggler has to get all the medals, but at what cost? The ball with feet format proves a form well adapted to surviving in the overgrown labyrinth of strange and masochistic shareware platform games.
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<br><center><img src="BallPics/natureclan1.png"><img src="BallPics/natureclan2.png"><img src="BallPics/natureclan3.gif"></center><br>
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<b>NATURE CLAN:</b><br><br>
No relation to X Clan. Actually not a game but an entire franchise, produced by bootleg famicom developers "Nice Code" and discoverable in shady-looking multicarts the world over (including at the V&A!) - encompassing titles like Pindable Crystal Ball, Forest Adventure, and my personal favourite Sky Dreamer. All of these games star "Nature Clan", a tiny but indomitable red ball with feet and eyes in the Lolo tradition. Long past the Famicom's official expiry date Nature Clan has hung in there with his series of original and sometimes beautiful adventures.. It's easy to mock pirate games but I take real pleasure in the thought that they are keeping the tradition of gormless "generic" videogame entities alive in new contexts - passing on to new generations the vague sensation of having once been a ball with feet.
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<br><center><img src="BallPics/yumenikki.png"></center><br>
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<b>YUME NIKKI:</b><br><br>
Yume Nikki populates the dream unconscious in part with the stranger fragments of videogames long expired strange hands, famicom worlds. In one location we come across the "wheelies", a mysterious group of painted discs with powerful, muscular legs. The musculature suggests a vigorous lifestyle, and they are undressed and unshod, suggesting connection to the earth and perhaps a condition of grace. Maybe it's accidental, but something about them also reminds me of early depictions of biblical angels, shown as floating, winged wheels covered in eyes. They're strange, charged figures... balls with feet may no longer be as familiar a presence on our screens. But Yume Nikki suggests they live on regardless in the collective dream life, nourished by that mysterious soil, which they ultimately came from, and will ultimately return to again.
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<center><img src="BallPics/lolo.png"><img src="BallPics/lolo.png"><img src="BallPics/lolo.png"><img src="BallPics/lolo.png"><img src="BallPics/lolo.png"></center>
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<center><b>SEMANTICS REVUE:</b><br><br></center>
What is a ball... for that matter what are feet? These questions may never be answered by mankind, for they belong more properly to the realm of "god". But in examining the iconography of ball with feet I have come up with some rough rules and values which I hope to enshrine.<br><br>
1. The main body of the creature should either be a ball or substantially ball-like (eg "egg" "deflated ball" "ball of fluff"). Yet already we are back in the realm of private judgement as many things can be described this way. I can only follow my heart.<br><br>
2. The ball forms both the head and the torso.<br><br>
3. Ideally the feet should be attached to the ball by as short a range as possible. They are "feet" and not "legs".<br><br>
4. Hands are optional but discouraged.<br><br>
5. Facial features should ideally be minimal.<br><br>
6. The feet should be stubby.<br><br>
7. The ball should be cute.<br><br>
These seven tenets are being nailed to churchdoors worldwide as I type.
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<center><img src="BallPics/babylonianzodiac.png"></center>
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<center><b>ORIGINS OF THE BALL:</b><br><br></center>
In my opinion "ball with feet" is common in videogames for the following reasons:<br><br>
- the ball shape is simple and easily identified on a cluttered screen - it can be rendered at even very low resolutions<br><br>
- the ball shape fits well within a collision box while remaining somewhat more organic looking than a square.<br><br>
The feet are harder to account for on a purely technical level - but this is key, since the history of videogames is not just that of technical limitations but also of the continuous effort to mitigate or push against those limitations. Between the human and the machine lies a broad range of give-and-take - as the human adapts to the rhythms of the machine, the machine itself takes on more human face. The ball becomes the ball with feet, marking off the point where consciousness and material become ambiguously reconciled.<br><br>
Also, the walk cycle for a ball with feet is easy to animate.
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<center><img src="BallPics/bosch-eggman.jpg"></center>
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<center><b>SYMBOLIC ROLE:</b><br><br></center>
The circle has long been regarded as the most perfect of forms for the uniformity which it represents; the feet, as the body's connection to earthly matter ("feet of clay", etc). A ball with feet is therefore a kind of synthesis of the divine with the material, and could therefore be seen as a kind of "ultimate lifeform", the final purpose of which to either destroy or rule over the imperfect synthesis that is mankind. We prefigure this day of reckoning in our dreams, and our art.
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<center><img src="BallPics/lolo3.gif"></center>
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<a href = "http://www.harmonyzone.org">Back</a>
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♥BALL WITH FEET♥
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***BALL WITH FEET - A TRIBUTE*** |
![](BallPics/lolo.png)
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**INTRODUCTION:**
Videogames as mass cultural form busily scavenge all the cabinets of mankind. In the process they find rare trinkets and horrible debris, old fads and styles, cultural terrors and unarticulateable desires and night bogeys. Rarefied mystic symbols are placed next to "meat" and "coin" as things for your guy to rove around and eat. In the process new structures of meaning and value emerge, haunted by figures both familiar and strange. Among them is a ball with feet.
On this webpage I propose to explore the various manifestations of a dream: that of some form of cute ball who walks around on little feet. Definitions and technical specifics are listed below this very provisional and personal catalog.
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**A LINK TO THE PAST:**
This game, the "AAA" of its day, represented a bold effort at shaping the traditionally bizarre iconography and sense of place in the zelda games into some kind of coherent whole. The abstract plains and rock formations of the first game were successfully converted into pieces of high fantasy. But as if in a dream the repressed videogamey bits and pieces eventually make their disguised return, in the form of a shadowy mirror realm, a "dark world" that travesties the main kingdom by filling it up again with all the goofy nonsense stuff it had initially discarded. Illegible gremlin people, rock structures, insect skeletons, ruins, off-brand videogame protagonists (Link briefly turns into a bunny!) - and in this familiar world, one of the first things we encounter is a beautiful little ball with feet, waddling forth as if to welcome us home.
The ball in this game is called "BULLY'S FRIEND" and tells us that "I was always changing my mind, so I turned into a ball." If only it were that simple!! He is constantly pursued and bounced around by a kind of dinosaur guy, but does not refer to this in his dialog, and the goofy "boing" sounds and constant expression(?) of happy delight lead us to question whether he actually feels any kind of discomfort from this. Maybe it's a consensual relationship? Either way he seems pretty happy to run around the mountaintop forever. I wish him well in pursuing his desires.
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**ADVENTURES OF LOLO:**
Perhaps the paragon of orthodox ball with feet imagery in videogames - - perhaps the paragon of videogame characters in general? Staring eyes, expressionless face, gloves, sneakers, a name which is just the same short syllable repeated twice and ending in "-o", Lolo has it all! A ball with feet is all he is, and all he is content to be. Truly, he has much to teach us.
But the fact that Lolo is situated so firmly and explicitly inside of this tradition also incidentally casts light on some lesser known aspects of it. For example, we also find a rare example of a "girl ball" in the person of Lolo's girlfriend, Lala, who is indistinguishable from him except that she is pink and wears a large ribbon. Secondly, delving into the franchise's origins as the "Eggerland" series for MSX turns up this powerful image:
Here we see that Lolo is in fact covered with hair! Imagine the possibilities! That the contemporary videogame industry should take detailed hair rendering technology as the definining measure of success, while failing to turn to so obvious an application, seems to me an injustice bordering on a crime.
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**DOOR-DOOR:**
How many aliens can you shut up? Despite the brutality of his mission, Door-Door protagonist Chun ("a small, spherical animal outfitted with a baseball cap" according to Wikipedia) is in fact very cute. This was Enix's first game, based on a contest submission, which raises interesting questions - was Chun's design a deliberate attempt to echo established successes such as Q-Bert and Pac-Man, in an effort to break into the industry? Is this evidence of a kind of background consensus over what a videogame character "should be" at the time? The egg shape says Im cute, while the sassy cap says, watch out.
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**AMERICAN DREAM:**
One affordance of the ball with feet shape is that the generic "ball" can be replaced with more specific kinds as a simple and easy way to get something more appropriate to various thematic settings - for example a soccer ball, or a globe. In this game you play a roulette ball exploring a landscape of various casinos in search of the titular "american dream, becoming obscenely wealthy via blind submission to statistically rigged games of chance, also known as meritocracy. The dinky, ingenuous quality of the little ball also provided a frame with which to examine various sublimated anxieties about the american setting as hallucinated from 6000 miles away.
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**FINAL SET TENNIS:**
A case in point this cheerful tennis entity. In my research I am unable to determine whether he appears at any other point of the game than in the credits, possibly operating upon the same principles as pornographic mahjong variants.
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**MR BLOOPY:**
An interesting missing link between purely gelatinous blobs like Jerry Boy and the balls with feet we all know and love. Mr Bloopy appears at first to be a highly classical form of slime blob - but he is also able to leap into the air by extruding a pseudopod shaped roughly like a human foot! Ancestor, parallel evolution or just weird?
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**CHACK'N POP**
As baby chickens are potentially the closest this world has come to producing real life balls with feet (certain frogs come close - but chickens are bipedal) it's not surprising this affordance would be seized within the industry. The New Zealand Story is another strong contender- but my personal vote goes to Chack'n Pop, as much for the name as anything. Interestingly Wikipedia does not seem to recognize it a chicken, describing Chack'n instead as "a small yellow creature (later recolored green) with extendable legs".
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**BOMBERMAN 64: THE SECOND ATTACK:**
Sufficiently cartoonish rabbitoids can also approach ball with feet status, for example in Sunsoft's Trip World. But I prefer the otherwise egregious "Pommy" animal from Bomberman 64: The Second Attack in part because of the above chart, which not only links together various kinds of ball-likes in some kind of natal stage chart but also details the precise amounts of [FRUIT] [MEAT] and [SWEETS] required for each stage.
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**PAC-MAN:**
Here is the question which has riddled all the scholars: does Pac-Man have feet? The early attempts at portraying just what Pac-Man "is" are various enough to allow for genuine doubt about this question and it's possible his legs were the addition of a later hand, like some of the heretical testaments. Eventually it became plain that all popular videogame characters have to be humanoid enough to pose for promotional drawings and possibly star in their own cartoons, and his corporate image stabilized into containing little red booties and gloves as well.
But some of the earlier designs are still disconcerting, and we can imagine Pac-Man frantically mutating, like The Thing, emitting and discarding various forms of pseudopod and facial expression until finding some combination that fit. Maybe somewhere under there he's still just a hockey puck.
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**GIMMICK!:**
Is Gimmick! a ball or just a kind of baggy plushie dinosaur thing? If we let him in, who next? The dinosaurs from Bubble Bobble? The guys from UFOuria? Hello Kitty? Can't most entities on this planet be glossed as some variety of ball, with some variety of feet? Cannot I myself...?
Poised on the brink of a terrifying realization I am hasty to shut the door on these kinds of speculative questions. And yet Gimmick! remains inside. I believe he counts due to the size of his eyes and fact that they exist squarely in the middle of his "torso", rather than being part of a seperate "head" segment. But don't push it.
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**~~CURIOSITIES CORNER~~~**
**FANTASY ZONE:**
Noted plastic spaceship and [traumatised war criminal](http://www.vgmuseum.com/end/arcade/c/fz28g.htm) Opa-Opa has among many other delightful features the ability to sprout little feet when walking around on the ground - similar to Pop'N'TwinBee, two cute spaceship things with little sneakers and arms permanently attached. While not really a ball Opa-Opa clearly draws from something of a similar visual tradition.
I continue to cherish the idea that someday there'll be a game about a cute cartoon car who walks around on little shoes just projecting from his undercarriage.
**BALLZ:**
From Petz producers P.F. Magic comes a sort of prototype for the ball technology utilized in that game. The Ballz represent the missing link between the classic ball with feet design and strange hyerspecialized offshoots such as Vectorman.
**COOL SPOT:**
Balls with feet are oddly underrepresented in the "mascot boom" of the 1990s, possibly because it's harder to copyright a geometric primitive. A notable exception is corporate toady and stooge of Big Soda, Cool Spot, who is really more of a disc with feet maybe reflecting the fundamental cynicism of the project.... You think this is a costume, man? This is a way of LIFE!
**EGGY:**
A suggestive missing link between the spaceship-with-feet and ball-with-feet species, EGGY is actually a fairly sophisticated and non-cartoonish form of bipedal robot. But his goofy name and egglike structure still connect him to this lineage. Is EGGY an advanced, futuristic form of ball with feet - or is he in fact a distant ancestor, a clunky metal version of the advanced smartpolymer bioorganic entities that would come to succeed him, us, as rulers of the planet?
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**DIZZY THE EGG:**
The popular british mascot character. I actually don't much care for Dizzy outside of his name, but it's interesting that the art for him mostly takes pains to show his limbs as sort of hovering alongside his body rather than being directly connected - shades of Ballz, but also Rayman. A possible link?
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**HORACE GOES SKIING:**
Not quite a ball - or is he just a ball wearing a little smurf hat? The mystery of Horace's exact physiology is just one of his many delights. Note also the long, raggedy eyeholes, which are either eyes or just holes extending directly through his head depending on representation. Horace started as a humble pac-man clone ("Hungry Horace", 1982) but only truly blossomed when the same sprite was dropped into the context of this strangely quotidian skiing game. He appeared in many other games of different genres but was unchanging in his sprite, his mystery and his appeal.
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**Q-BERT:**
A kind of.. mysterious talking ball / muppetlike entity who lives on, or is in conflict with, a pyramid of cubes. Q-Bert's main distinguishing feature is his prominent hooverlike mouth - or nose, or possibly beak? While you may think this disqualifies him from being considered a ball proper, I think it constitutes an interesting and neglected avenue in the constant struggle to "personify" the balls somewhat. While Chun from Door-Door had his cap, and various later forms of ball would have full faces, Q-Bert's low resolution nature meant the developers had to resort to more drastic structural solutions.
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**MS PAC-MAN:**
Not necessarily his wife - Ms Pac-Man was actually a bootleg game produced by a completely different group and then sold to the american company representing the original Namco product. While not up on my peerage I believe this makes her something more like Pac-Man's second cousin, or possibly his niece. Regardless - we know that Ms Pac-Man canonically has legs, since they are represented so prominently on the cabinet art to fairly disconcerting effect. The question of "ball with feet" vs "ball with legs" is ongoing and unsettled and will perhaps never be resolved until the final defeat of the dread god Eros. But it has to be said that all the offbrand Pac variants look better every year that the singular hegemonic Pac presence accrues yet more power for his ghoulish media empire. Bring back Pac Baby!!
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**KIRBY:**
YES I've seen the picture of Kirby where he has human feet and NO I don't ever want to look at it again.
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|
**BARKLEY, SHUT UP AND JAM: GAIDEN:**
A game with a wide variety of ball-related monsters. The most interesting for our purposes are the "Ball Droids", hollow metal balls with little legs and an antenna that shoots a powerful ray. For some reason I have the impression that basketballs are stored inside the ball droids to be cleaned, and that they therefore represent a sort of feral washing machine.
|
| |
| --- |
|
**POKEMON:**
There are now over 800 pokemon, which is a full 750 more than I can remember. Of these a substantial variety are some form of ball with feet, from Gen 1 alone we have Venonat, Jigglypuff, the Polywhirl family and likely many others. I like Jigglypuff the best for its precious little tuft.
|
| |
| --- |
|
**DIG-DUG:**
The "Pooka", aka Deepman, is a ball with feet which has admirably adapted to subterranean additions by the simple expedient of adding some goggles. Somehow this combination works well enough for us not to question it further... Deepman lives here, he seems to fit in, he is taking adequate safety precautions. Are you?
|
| |
| --- |
|
**YOSHI'S ISLAND:**
The Mario series has so many kinds of balls with feet that it would almost unbalance the list to try and put them all in - two especially notable examples being Bob-Ombs and the lovely Wanderin' Gooms from Wario Land. So I will just focus on one personal favourite.
The "mildes" from Yoshi's Island are notable mainly for being, as their name suggests, the single least threatening enemies in the game. Even the shy guys can sometimes get you with their haphazard wandering movements - the metal, spikey walking guys resist being eaten or stepped on - various other enemies have some sort of resistance, or speciality, or form of surprise attack. The mildes' only purpose is to amble slowly forwards, and then to die. You can pop them underfoot, you can eat them for more ammo, you can shoot them with an egg if you really want to be over the top. They are comically overdestructable. And yet they have a cheery, aimless smile at all times, and seem content to just wander forwardsin this fashion. The combination of this contentness with their fragile superfluity makes them a mysterious and memorable presence.
A milde actually becomes a boss character at one point in the game - it just keeps wandering as before, except now it's very large. Its gimmick is to split into two smaller mildes when slammed on, suggesting balls with feet reproduce by a form of cell division.
|
| |
| --- |
|
**~~INDIE CORNER~~~**
**CRYPT UNDERWORLD:**
Once again it is the task of "indie games" to boldly reinvent an overlooked classic of form. In this case - a promotional screenshot for smash hit upcoming mall purgatory simulacrum Crypt Underworld, in which we see a mysterious yet immediately beguiling entity known only as "BUMBO", consisting entirely of billboarded ball sprites. BUMBO pushes against ball with feet orthodoxy by (1) apparently being six feet high and (2) having, instead of any kind of face, the terse but fascinating declaration.. BUMBO! The striking power that results may yet make this spirit something of a Beau Brummel figure for the next generation of balls with feet.
**PIKUNIKU:**
This ball has long legs, possibly evolved to be able to eat high pieces of foliage. A nice variant. And with physics!
**JIGGLY ZONE:**
A collaboration between [Sylvie](https://www.glorioustrainwrecks.com/games/*/sylvie) and [Hubol](http://www.hubolhubolhubol.com/), both longtime developers with a deep canon of ball-based works. Jiggler has to get all the medals, but at what cost? The ball with feet format proves a form well adapted to surviving in the overgrown labyrinth of strange and masochistic shareware platform games.
|
| |
| --- |
|
**NATURE CLAN:**
No relation to X Clan. Actually not a game but an entire franchise, produced by bootleg famicom developers "Nice Code" and discoverable in shady-looking multicarts the world over (including at the V&A!) - encompassing titles like Pindable Crystal Ball, Forest Adventure, and my personal favourite Sky Dreamer. All of these games star "Nature Clan", a tiny but indomitable red ball with feet and eyes in the Lolo tradition. Long past the Famicom's official expiry date Nature Clan has hung in there with his series of original and sometimes beautiful adventures.. It's easy to mock pirate games but I take real pleasure in the thought that they are keeping the tradition of gormless "generic" videogame entities alive in new contexts - passing on to new generations the vague sensation of having once been a ball with feet.
|
| |
| --- |
|
**YUME NIKKI:**
Yume Nikki populates the dream unconscious in part with the stranger fragments of videogames long expired strange hands, famicom worlds. In one location we come across the "wheelies", a mysterious group of painted discs with powerful, muscular legs. The musculature suggests a vigorous lifestyle, and they are undressed and unshod, suggesting connection to the earth and perhaps a condition of grace. Maybe it's accidental, but something about them also reminds me of early depictions of biblical angels, shown as floating, winged wheels covered in eyes. They're strange, charged figures... balls with feet may no longer be as familiar a presence on our screens. But Yume Nikki suggests they live on regardless in the collective dream life, nourished by that mysterious soil, which they ultimately came from, and will ultimately return to again.
|
![](BallPics/lolo.png)![](BallPics/lolo.png)![](BallPics/lolo.png)![](BallPics/lolo.png)![](BallPics/lolo.png)
| |
| --- |
|
**SEMANTICS REVUE:**
What is a ball... for that matter what are feet? These questions may never be answered by mankind, for they belong more properly to the realm of "god". But in examining the iconography of ball with feet I have come up with some rough rules and values which I hope to enshrine.
1. The main body of the creature should either be a ball or substantially ball-like (eg "egg" "deflated ball" "ball of fluff"). Yet already we are back in the realm of private judgement as many things can be described this way. I can only follow my heart.
2. The ball forms both the head and the torso.
3. Ideally the feet should be attached to the ball by as short a range as possible. They are "feet" and not "legs".
4. Hands are optional but discouraged.
5. Facial features should ideally be minimal.
6. The feet should be stubby.
7. The ball should be cute.
These seven tenets are being nailed to churchdoors worldwide as I type.
|
![](BallPics/babylonianzodiac.png)
| |
| --- |
|
**ORIGINS OF THE BALL:**
In my opinion "ball with feet" is common in videogames for the following reasons:
- the ball shape is simple and easily identified on a cluttered screen - it can be rendered at even very low resolutions
- the ball shape fits well within a collision box while remaining somewhat more organic looking than a square.
The feet are harder to account for on a purely technical level - but this is key, since the history of videogames is not just that of technical limitations but also of the continuous effort to mitigate or push against those limitations. Between the human and the machine lies a broad range of give-and-take - as the human adapts to the rhythms of the machine, the machine itself takes on more human face. The ball becomes the ball with feet, marking off the point where consciousness and material become ambiguously reconciled.
Also, the walk cycle for a ball with feet is easy to animate.
|
![](BallPics/bosch-eggman.jpg)
| |
| --- |
|
**SYMBOLIC ROLE:**
The circle has long been regarded as the most perfect of forms for the uniformity which it represents; the feet, as the body's connection to earthly matter ("feet of clay", etc). A ball with feet is therefore a kind of synthesis of the divine with the material, and could therefore be seen as a kind of "ultimate lifeform", the final purpose of which to either destroy or rule over the imperfect synthesis that is mankind. We prefigure this day of reckoning in our dreams, and our art.
|
![](BallPics/lolo3.gif)
[Back](http://www.harmonyzone.org)
| http://harmonyzone.org/ballwithfeet.html |
<HTML>
<HEAD>
<TITLE>My Kites!</TITLE>
</HEAD>
<BODY TEXT="#FFFFFF" BGCOLOR="#000000" LINK="#FFFF00" VLINK="#33CCFF" ALINK="#FF0000">
<p>
Here is my BLAH kite page.... you will only find pictures of me
and my kites here.. and thats it :) These pictures are thumbnailed.
Be sure to click on them for a larger view.
</p>
<p>
<FONT SIZE=+1>
This is one of the more recent additions to my kite bag! My
very own <A HREF="http://www.frontiernet.net/~aquarius/pizazz/">Pizazz</A>,
custom built by Dick Barnes!
</FONT>
</p>
<p>
Go check out my pictures (no page yet though) of my Peter
Betancourt Bad Boy 2 <a
href="http://www.frontiernet.net/~aquarius/pbsk">PBSK</a>
</p>
<p>
Sorry for the somewhat fuzzy picutres.... I took these with the
WRONG camera. *sniffle*
</p>
<p>
Good Winds!
</p>
<table>
<tr>
<td>
<hr width=100%>
<p>
<a href="delta.jpg"><img SRC="smdelta.jpg" ALIGN=left></a>
This is my Zephyr Delta that was invented and patented by
a fellow flier friend of mine, Ed Grauel. This was the
first kite I ever built.
</p>
<br>
</td>
</tr>
<tr>
<td>
<hr width=100%>
<p>
<a href="rok.jpg"><img SRC="smrok.jpg" ALIGN=left></a>
Ths is the 3rd kite that I built.... This rokkakuis 45
inches tall by 40 inches wide. I forget what the sail
area is, but who cares. This was also my first attempt
at applique. I wont tell you where all of the mistakes
are if you promise not to look for them :)
</p>
<br>
</td>
</tr>
<tr>
<td>
<hr width=100%>
<p>
<a href="parasled.jpg"><img SRC="smparasled.jpg"
ALIGN=left></a>
This is my favorite of the kites I have built (my
fourth!) This is a 23 square foot (or so that's how
it worked out on paper) Double Parasled. The plans
were taken out of Kitelines, Fall 1994. I didnt want
to build anything near as big as the original, (144 sq
ft) so I decided to go small for the first one. Next
one will probably be either 36 or 64 sq ft. We will
see next spring. It pulls amazingly well for such a
relatively small kite.
</p>
<br>
</td>
</tr>
<tr>
<td>
<hr width=100%>
<p>
<A HREF="circoflex.jpg"><img SRC="smcircoflex.jpg"
ALIGN=left></a>
This was a spur of the moment build that went along side
of the Double Parasled. It is called a Circoflex. I first
saw an AMAZING one at Ocean City Kitefest two years ago.
I got the plans from the fellow who had one made out of a
silver mylar material. This one is 7 feet in diameter, and
sparred in 1/8 inch fiberglass rod. Big mistake. The
fiberglass is too fragile (sneeze on it and it kinks, but
not breaks). Next time I will go for carbon. It was very
inexpensive to build. Even though you cant tell it so well
from this particular picture (I have more to scan) it is a
medium blue transparent material. This particular kite
took me approximately 3 hours to build from start to stop.
(Yes! Even bridling! AWESOME!) My future plans are to
build a small one to fly inside of it, and maybe a bigger
one to go outside of this one, in different colors.
</p>
<p>
It was orginally designed in Europe by Helmut Schiefer and
Ton Oostveen, and I got the plans from Mike Dallmer. If
you are interested in the plans email me and I can see
what I can do for you.
<A HREF="mailto:aquarius@frontiernet.net">aquarius@frontiernet.net</A>
</p>
<br>
</td>
</tr>
<tr>
<td>
<hr width=100%>
<p>
<a href="catherineswheel.jpg"><img
SRC="smcatherineswheel.jpg" ALIGN=left></a>
Speaking of Ocean City, I picked up this Cahtherine's Wheel from
<A HREF="http://www.kiteloft.com">The Kite Loft</A> right on
the boardwalk. I just had to do it. One of my winter time
plans is to build a smaller one of these, and maybe a larger
one. I have to be sure that I will have a large enough kite to
build one of the larger ones though. This one (I am not sure
how big it is) is just about right for my double parasled, but
any larger and it would over power it and drag the line out toooooo far.
</p>
<br>
</td>
</tr>
<tr>
<td>
<hr width=100%>
<p>
<a href="flowform.jpg"><img SRC="smflowform.jpg"
ALIGN=left></a>
This is my 12.5 sq ft flowform that I picked up from Scott
Richardson. This is my
kite-that-will-fly-almost-anytime-there-is-wind. It's
great. It has more pull than the 8 sq ft (duhhh!!!) and it
about equals the 16 sq ft, but it is more stable in the
sky. Yet another wintertime project is to build another one.
</p>
<br>
</td>
</tr>
<tr>
<td>
<hr width=100%>
<p>
<a href="thf.jpg"><img SRC="smthf.jpg" ALIGN=left></a>
This is the very first *REAL* kite that I bought myself.
It is a Team High Fly Pro/Am. I picked it up here in
Rochester from a friend. This is by far one kite I will
never get rid of for a few reasons: It *always* flys,
especially in wind its not supposed to, even though it is
3/4 oz ripstop and framed in Beman Carbon Strong 14
sticks. Nope..no wrap, no Icarex, but it flys in almost no
winds if you work it right. It tracks on rails and is very
easy to fly (I taught about 12 people to fly on it from
June to September alone!) Its only downfall is it is
strictly a team/precision kite. No trick ability at all,
unless you are maybe.... Dodd Gross? :) It is still an
excellent flyer, and it was my first *sniff*
</p>
<br>
</td>
</tr>
<tr>
<td>
<hr width=100%>
<p>
<a href="nowind.jpg"><img SRC="smnowind.jpg"
align=left></a>
Here is my nowind/indoor kite. A friend of mine built this
one for me. Isnt it cute? ;)
</p>
<br>
</td>
</tr>
<tr>
<td>
<hr width=100%>
<p>
<a href="bermuda.jpg"><img SRC="smbermuda.jpg"
ALIGN=left></a>
Last but not least is my bermuda. I picked this up in a
local toy store in Buffalo. It is 36 inches in diamater
and flies very well when it wants to. My only qualm is
that it has to be tweaked depending on the wind
conditions, but by tweaking, I can extend its wind range.
I added the 2nd set of tails for dramatic effect. I also
built a clone of this particular kite just to see if I
could. I did that (it was my 2nd kite even) and that is
where the 2nd set of tails normally live. It looks really
cool to have both of the bermudas in the air at the same
time. They just kinda dance around and those long 30 foot
tails just swish around in the breeze. Tres cool.
</p>
<br>
</td>
</tr>
<tr>
<td>
<hr width=100%>
<p>
<a href="crossdeck.html"><img SRC="smcrossdeck.jpg"
ALIGN=left></a>
For a (not so) new addition to my kite bag, I made this
crossedeck from plans by <a
href="http://www.kite.com/kite/kitedex.htm">Carl Crowell</a>. I
took this kite to the <a href="http://www.aka.kite.org">AKA</a>
Grand Nationals, 1998, held in Ocean Shores Washington.
Though I didnt place in the Cellular category, I did place
third overall for Novice Kitemakers. Scary, I am now
considered a Master kite builder. I still have a hard
time realizing that.
</p>
<br>
</td>
</tr>
</table>
<CENTER>
<hr width=100%>
<img SRC="bugbd.gif" >
</CENTER>
</BODY>
</HTML>
|
My Kites!
Here is my BLAH kite page.... you will only find pictures of me
and my kites here.. and thats it :) These pictures are thumbnailed.
Be sure to click on them for a larger view.
This is one of the more recent additions to my kite bag! My
very own [Pizazz](http://www.frontiernet.net/~aquarius/pizazz/),
custom built by Dick Barnes!
Go check out my pictures (no page yet though) of my Peter
Betancourt Bad Boy 2 [PBSK](http://www.frontiernet.net/~aquarius/pbsk)
Sorry for the somewhat fuzzy picutres.... I took these with the
WRONG camera. \*sniffle\*
Good Winds!
| |
| --- |
|
---
This is my Zephyr Delta that was invented and patented by
a fellow flier friend of mine, Ed Grauel. This was the
first kite I ever built.
|
|
---
Ths is the 3rd kite that I built.... This rokkakuis 45
inches tall by 40 inches wide. I forget what the sail
area is, but who cares. This was also my first attempt
at applique. I wont tell you where all of the mistakes
are if you promise not to look for them :)
|
|
---
This is my favorite of the kites I have built (my
fourth!) This is a 23 square foot (or so that's how
it worked out on paper) Double Parasled. The plans
were taken out of Kitelines, Fall 1994. I didnt want
to build anything near as big as the original, (144 sq
ft) so I decided to go small for the first one. Next
one will probably be either 36 or 64 sq ft. We will
see next spring. It pulls amazingly well for such a
relatively small kite.
|
|
---
This was a spur of the moment build that went along side
of the Double Parasled. It is called a Circoflex. I first
saw an AMAZING one at Ocean City Kitefest two years ago.
I got the plans from the fellow who had one made out of a
silver mylar material. This one is 7 feet in diameter, and
sparred in 1/8 inch fiberglass rod. Big mistake. The
fiberglass is too fragile (sneeze on it and it kinks, but
not breaks). Next time I will go for carbon. It was very
inexpensive to build. Even though you cant tell it so well
from this particular picture (I have more to scan) it is a
medium blue transparent material. This particular kite
took me approximately 3 hours to build from start to stop.
(Yes! Even bridling! AWESOME!) My future plans are to
build a small one to fly inside of it, and maybe a bigger
one to go outside of this one, in different colors.
It was orginally designed in Europe by Helmut Schiefer and
Ton Oostveen, and I got the plans from Mike Dallmer. If
you are interested in the plans email me and I can see
what I can do for you.
[aquarius@frontiernet.net](mailto:aquarius@frontiernet.net)
|
|
---
Speaking of Ocean City, I picked up this Cahtherine's Wheel from
[The Kite Loft](http://www.kiteloft.com) right on
the boardwalk. I just had to do it. One of my winter time
plans is to build a smaller one of these, and maybe a larger
one. I have to be sure that I will have a large enough kite to
build one of the larger ones though. This one (I am not sure
how big it is) is just about right for my double parasled, but
any larger and it would over power it and drag the line out toooooo far.
|
|
---
This is my 12.5 sq ft flowform that I picked up from Scott
Richardson. This is my
kite-that-will-fly-almost-anytime-there-is-wind. It's
great. It has more pull than the 8 sq ft (duhhh!!!) and it
about equals the 16 sq ft, but it is more stable in the
sky. Yet another wintertime project is to build another one.
|
|
---
This is the very first \*REAL\* kite that I bought myself.
It is a Team High Fly Pro/Am. I picked it up here in
Rochester from a friend. This is by far one kite I will
never get rid of for a few reasons: It \*always\* flys,
especially in wind its not supposed to, even though it is
3/4 oz ripstop and framed in Beman Carbon Strong 14
sticks. Nope..no wrap, no Icarex, but it flys in almost no
winds if you work it right. It tracks on rails and is very
easy to fly (I taught about 12 people to fly on it from
June to September alone!) Its only downfall is it is
strictly a team/precision kite. No trick ability at all,
unless you are maybe.... Dodd Gross? :) It is still an
excellent flyer, and it was my first \*sniff\*
|
|
---
Here is my nowind/indoor kite. A friend of mine built this
one for me. Isnt it cute? ;)
|
|
---
Last but not least is my bermuda. I picked this up in a
local toy store in Buffalo. It is 36 inches in diamater
and flies very well when it wants to. My only qualm is
that it has to be tweaked depending on the wind
conditions, but by tweaking, I can extend its wind range.
I added the 2nd set of tails for dramatic effect. I also
built a clone of this particular kite just to see if I
could. I did that (it was my 2nd kite even) and that is
where the 2nd set of tails normally live. It looks really
cool to have both of the bermudas in the air at the same
time. They just kinda dance around and those long 30 foot
tails just swish around in the breeze. Tres cool.
|
|
---
For a (not so) new addition to my kite bag, I made this
crossedeck from plans by [Carl Crowell](http://www.kite.com/kite/kitedex.htm). I
took this kite to the [AKA](http://www.aka.kite.org)
Grand Nationals, 1998, held in Ocean Shores Washington.
Though I didnt place in the Cellular category, I did place
third overall for Novice Kitemakers. Scary, I am now
considered a Master kite builder. I still have a hard
time realizing that.
|
---
![](bugbd.gif)
| http://www.frontiernet.net/~aquarius/kites/ |
<head><title>Not Acceptable!</title></head><body><h1>Not Acceptable!</h1><p>An appropriate representation of the requested resource could not be found on this server. This error was generated by Mod_Security.</p></body></html> | Not Acceptable!# Not Acceptable!
An appropriate representation of the requested resource could not be found on this server. This error was generated by Mod\_Security.
| http://patorjk.com/software/taag/ |
<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
<html>
<head>
<title>The Death Clock - When Am I Going To Die?</title>
<meta name="keywords" content="Death Clock,Deathclock" >
<meta name="description" content="Death Clock: The Internet's friendly reminder that life is slipping away..." >
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'&URL_Zip=' + zip + '&URL_Country=' + countryr + '&URL_EMail=' + email);
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}
if((mymonth==3) || (mymonth==5) || (mymonth==8) || (mymonth==10)) {
if(myday>30) {
alert("Only 30 days in the month you have selected.");
document.main.day.value = 30;
return false;
}
}
if((mymonth==1) && (myday > 29)) {
alert("The maximum number of days in February is 29.\n"+myday+" is invalid.");
document.main.day.value = 29;
return false;
}
if( !LeapYear(myyear) && (mymonth == 1) && (myday > 28)) {
alert("There are only 28 days in February "+myyear);
document.main.day.value = 28;
return false;
}
if(myyear < 1900) {
alert("You must enter a year after 1899.");
return false;
}
if(myyear > 2100) {
alert("You must enter a year before 2100.");
return false;
}
if(!myyear || myyear == 0) {
alert("You must enter a year of birth.");
document.main.year.value = 1973;
return false;
}
return true;
}
function startDeath(form) {
if(okForm(form.day.value,form.month.selectedIndex,form.year.value)) {
trueSex = form.sex.options[form.sex.selectedIndex].text;
trueMode = form.mode.options[form.mode.selectedIndex].text;
deathwin.src = BASE + "dw.cfm?Day=" + form.day.value + "&Month=" + (form.month.selectedIndex+1) + "&Year=" + form.year.value + "&Sex=" + trueSex + "&Mode=" + trueMode + "&bmi=" + form.bmi.value + "&smoker=" + form.smoker.value;
launchwindow(deathwin);
}
return false;
}
// --------------------------------------------------------------
// Do oue BMI Calculations
// --------------------------------------------------------------
function MM_BMI()
{
br="ie";
if (navigator.appName == "Netscape")
{
br="ns";
}
ver = navigator.appVersion.substring(0,1);
var comnt = "";
WVal = document.main.weight.selectedIndex;
w = eval('document.main.weight.options[WVal].text');
w = (w * 1);
HtfVal = document.main.htf.selectedIndex;
Htf = eval('document.main.htf.options[HtfVal].text');
HeightFeetInt = (Htf * 1);
HtiVal = document.main.hti.selectedIndex;
Hti = eval('document.main.hti.options[HtiVal].text');
HeightInchesInt = (Hti * 1);
HeightFeetConvert = HeightFeetInt * 12;
h = HeightFeetConvert + HeightInchesInt;
displaybmi = (Math.round((w * 703) / (h * h)));
if (HeightInchesInt > 11)
{
reminderinches = mod(HeightInchesInt,12);
document.main.hti.value = reminderinches;
document.main.htf.value = HeightFeetInt + ((HeightInchesInt - reminderinches)/12);
document.main.answer.value = displaybmi;
}
if (displaybmi <19)
{
comnt = "Underweight";
}
if (displaybmi >=19 && displaybmi <=25)
{
comnt = "Desirable";
}
if (displaybmi >=25 && displaybmi <=29)
{
comnt = "Prone to health risks";
}
if (displaybmi >=30 && displaybmi <=40)
{
comnt = "Obese";
}
if (displaybmi >40)
{
comnt = "Extremely obese";
}
com = eval('"Your Category is: " + comnt');
if(document.all)
{
Comment.innerHTML = com;
}
else
{
if (ver <= 4)
{
document.main.iComment.value = com;
}
else
{
var cElement = document.getElementById('Comment');
cElement.innerHTML = com;
}
}
ans = eval('"Your Body Mass Index is: <FONT Color=990000 Size = 3><B>" + displaybmi + "</B></FONT>"');
if(document.all)
{
Answer.innerHTML = ans;
}
else
{
if (ver <= 4)
{
ans = eval('"Your Body Mass Index is: " + displaybmi + ""');
document.main.iAnswer.value = ans;
}
else
{
var cElement = document.getElementById('Answer');
cElement.innerHTML = ans;
}
}
if(document.all)
{
Click.innerHTML = '';
}
else
{
if (ver <= 4)
{
document.iClick.document.open();
document.iClick.document.write('');
document.iClick.document.close();
}
else
{
var cElement = document.getElementById('Click');
cElement.innerHTML = '';
}
}
if (displaybmi >=25)
{
clk = "<A HREF = 'BMIPage2.cfm'><FONT Color=990000 Size = 3><B>Click Here</B></FONT></A> To Find Out What This Number Means To You";
if(document.all)
{
Click.innerHTML = clk;
}
else
{
if (ver <= 4)
{
document.iClick.document.open();
document.layers.iClick.top = 634;
document.layers.iClick.left = 170;
document.layers.iClick.width = 500;
document.iClick.document.write(clk);
document.iClick.document.close();
}
else
{
var cElement = document.getElementById('Click');
cElement.innerHTML = clk;
}
}
}
}
// -------------------------------------
// Load our BMI explanation Window
// ------------------------------------
function MM_Win()
{
var URL = 'Bmi.cfm';
var winVal = "location=no,scrollbars=no,menubars=no,toolbars=no,resizable=yes" +
",left=" + 20 + ",top=" + 100 + ",width=" + 350 + ",height=75";
myWindow4 = window.open (URL,"", winVal);
}
</script>
<link rel="stylesheet" type="text/css" href="main_style.css">
</head>
<body background="images/back.gif" bgcolor="#990000" text="#cccc99" link="#ff0000" vlink="#808000" alink="#ff0000" >
<center>
<script type="text/javascript"><!--
google_ad_client = "pub-6122620027504329";
google_alternate_ad_url = "http://deathclock.com/images/death_clock_banners/AdRotatorH.cfm";
google_ad_width = 728;
google_ad_height = 90;
google_ad_format = "728x90_as";
google_color_border = "660000";
google_color_bg = "7D2626";
google_color_link = "FFFFFF";
google_color_url = "DAA520";
google_color_text = "BDB76B";
//--></script>
<script type="text/javascript"
src="http://pagead2.googlesyndication.com/pagead/show_ads.js">
</script>
<center>
<p align="center">
<table width="600" cellspacing="0" cellpadding="0" border=0>
<tr valign="top">
<td height=21 bgcolor="#999966" width="150"><a href="http://www.deathclock.com"><img src="images/nav/home.gif" width=150 height=21 alt="home" border="0"></a></td>
<td colspan=2 bgcolor="#999966" width="450"><table cellpadding=0 cellspacing=0 border=0><tr><td height=21><p class="titletop"><b>Death Clock:</b> The Internet's friendly reminder that life is slipping away...</p></td></tr></table></td>
</tr>
<tr valign="top">
<td rowspan="2" bgcolor="#000000" width="150" align="center"><a href="index.cfm"><img src="images/nav/clockface.gif" width=150 height=107 alt="The Death Clock" border="0"></a><a href="obits.cfm" onMouseOver="over('obits')" onMouseOut="off('obits')"><img src="images/nav/obituaries.gif" width=150 height=30 alt="Obituary" border="0" name="obits"></a><a href="yourwill.cfm" onMouseOver="over('will')" onMouseOut="off('will')"><img src="images/nav/yourwill.gif" width=150 height=29 alt="Your Will" border="0" name="will"></a><a href="mortuary.cfm" onMouseOver="over('mort')" onMouseOut="off('mort')"><img src="images/nav/mortuary.gif" width=150 height=35 alt="Mortuary" border="0" name="mort"></a><a href="dlo.cfm" onMouseOver="over('letter')" onMouseOut="off('letter')"><img src="images/nav/deadletter.gif" width=150 height=30 alt="Dead Letter Office" border="0" name="letter"></a><a href="testament.cfm" onMouseOver="over('testament')" onMouseOut="off('testament')"><img src="images/nav/testament.gif" width=150 height=30 alt="Testament" border="0" name="testament"></a><a href="yourprayer.cfm" onMouseOver="over('prayer')" onMouseOut="off('prayer')"><img src="images/nav/yourprayer.gif" width=150 height=25 alt="Your Prayer" border="0" name="prayer"></a><img src="images/nav/pend.gif" width=150 height=36 alt="" border="0">
<table with="100%" cellpadding="10" cellspacing="0">
<tr><td>
<font class="titlered">Death Clock Poll</font>
<br>
<font class="main">
<SCRIPT LANGUAGE="JavaScript">
function checkPoll() {
for(i=0;i<document.Poll.Answer.length;i++) {
if(document.Poll.Answer[i].checked) {
return true;
}
}
return false;
}
</SCRIPT>
<font class="mainsmall">
<b>What was your preferred out of the following movies?</b>
</font>
<TABLE WIDTH="100%"><FORM ACTION="/index.cfm" NAME="Poll" ONSUBMIT="return checkPoll();" METHOD="POST">
<INPUT TYPE="hidden" NAME="PollID" VALUE="30">
<TR VALIGN="top">
<TD class="mainsmall"><INPUT TYPE="radio" NAME="Answer" VALUE="1" onClick="document.Poll.submit();"></TD>
<TD class="mainsmall">Slumdog millionaire</TD>
</TR>
<TR VALIGN="top">
<TD class="mainsmall"><INPUT TYPE="radio" NAME="Answer" VALUE="2" onClick="document.Poll.submit();"></TD>
<TD class="mainsmall">The Curious Case of Benjamin Button</TD>
</TR>
<TR VALIGN="top">
<TD class="mainsmall"><INPUT TYPE="radio" NAME="Answer" VALUE="3" onClick="document.Poll.submit();"></TD>
<TD class="mainsmall">Star Trek</TD>
</TR>
<TR VALIGN="top">
<TD class="mainsmall"><INPUT TYPE="radio" NAME="Answer" VALUE="4" onClick="document.Poll.submit();"></TD>
<TD class="mainsmall">X-Men Origins: Wolverine</TD>
</TR>
</FORM></TABLE>
<div align="right"><font class="mainsmall"><a href="view_polls.cfm">Archives</a></font></div></td></tr></table>
<br><br><br>
<!--<table width="80%" border="0" cellspacing="0" cellpadding="0" height="185">
<tr>
<td align="center"><a href="http://mhrusa.com/onlinescheduling/dvd_3day_nonumber.aspx?source=venffe30&adid=DTH-" target="_blank"><img src="images/hair_110x160.jpg" width="110" height="160" border="0"></a></td>
</tr>
</table>--></td>
<td bgcolor="#000000" width=250 class="intro"><img src="images/title.gif" width=241 height=51 alt="" border="0" vspace=5><br>
Welcome to the Death Clock(TM), the Internet's friendly reminder that life is slipping away...
second by second. Like the hourglass of the Net, the Death Clock will remind you just how
short life is.
</td>
<td bgcolor="#000000" width="200" valign="top"><img src="images/graveyard1.gif" width=200 height=108 alt="Graveyard" border="0" vspace=20></td>
</tr><tr valign=top>
<td rowspan="2" bgcolor="#999966" width="250"><nobr><img src="images/enterinfo.gif" width=138 height=37 alt="" border="0"><img src="images/buyit_blank.gif" width="112" height="37" alt="" border="0"></nobr>
<table cellspacing=0 cellpadding=5 border=0>
<form name="main" action="">
<tr>
<td width=100 align=right class="tdmain"><nobr>Day of Birth: </nobr></td>
<td width=150 class="tdmain"><input type="text" size=2 name="day" maxlength=2 class="formcolor" ></td>
</tr>
<tr>
<td width=100 align=right class="tdmain"><nobr>Month of Birth: </nobr></font></td>
<td width=150 class="main">
<select name="month" class="formcolor">
<option value="January" >January</option>
<option value="February" >February</option>
<option value="March" >March</option>
<option value="April" >April</option>
<option value="May" >May</option>
<option value="June" >June</option>
<option value="July" >July</option>
<option value="August" >August</option>
<option value="September" >September</option>
<option value="October" >October</option>
<option value="November" >November</option>
<option value="December" >December</option>
</select>
</td>
</tr>
<tr>
<td width=100 align=right class="tdmain"><nobr>Year of Birth: </nobr></td>
<td width=150 class="tdmain"><input type="text" size=4 name="year" maxlength=4 class="formcolor" value="1973"></td>
</tr>
<tr>
<td width=100 align=right class="tdmain"><nobr>Sex: </nobr></td>
<td width=150 class="tdmain"><select name="sex" class="formcolor">
<option value="m" >Male
<option value="f" >Female
</select></td>
</tr>
<tr>
<td width=100 align=right class="tdmain"><nobr>Mode: </nobr></td>
<td width=150 class="tdmain"><select name="mode" class="formcolor">
<option>Normal
<option>Pessimistic
<option>Sadistic
<option>Optimistic
</select></td>
</tr>
<tr>
<td width=100 align=right class="tdmain"><nobr>BMI<sup>*</sup>: </nobr></td>
<td width=150 class="tdmain"><select name="bmi" class="formcolor">
<option value="-25"><25
<option value="25">25
<option value="26">26
<option value="27">27
<option value="28">28
<option value="29">29
<option value="30">30
<option value="31">31
<option value="32">32
<option value="33">33
<option value="34">34
<option value="35">35
<option value="36">36
<option value="37">37
<option value="38">38
<option value="39">39
<option value="40">40
<option value="41">41
<option value="42">42
<option value="43">43
<option value="44">44
<option value="+45">>=45
</select></td>
</tr>
<tr>
<td width=100 align=right class="tdmain"><nobr>Smoking Status: </nobr></td>
<td width=150 class="tdmain"><select name="smoker" class="formcolor">
<option value="1">Smoker
<option value="0" selected>Non-Smoker
</select></td>
</tr>
<tr>
<td class="tdmain" colspan=2>
<sup>*</sup>To determine your Body Mass Index (BMI), enter your height and weight below.
</td>
</tr>
<tr>
<td colspan=2 width=250 align="center">
<input type="button" value="Check Your Death Clock" class="submitbutton" name="dc" onClick="startDeath(document.main)">
</td>
</tr>
</table>
<hr width="90%" size=2 noshade color="#000000">
<TABLE Align = "Center" CellPadding = "5">
<tr>
<td colspan=2 class="tdmain">
<center><b>The Lethal Danger of Being Fat</b></center>
Excess weight has a dramatic impact on one's health. The BMI (body mass index) is a way to measure your disease risk based on your height to weight ratio. People with a BMI of 25 to 29 are considered overweight and those with a BMI of 30 or more are considered obese.
</td>
</tr>
<TR>
<TD Width = "100" Align = "Right" CLASS = "tdmain">
<NOBR>
Height:
</NOBR>
</TD>
<TD Width = "150" CLASS = "tdmain">
<SELECT NAME = "htf" CLASS = "formcolor">
<OPTION VALUE="4" >4</OPTION>
<OPTION VALUE="5" Selected>5</OPTION>
<OPTION VALUE="6" >6</OPTION>
</SELECT>
Ft
<SELECT NAME = "hti" CLASS = "formcolor">
<OPTION VALUE="0" >0</OPTION>
<OPTION VALUE="1" >1</OPTION>
<OPTION VALUE="2" >2</OPTION>
<OPTION VALUE="3" >3</OPTION>
<OPTION VALUE="4" >4</OPTION>
<OPTION VALUE="5" >5</OPTION>
<OPTION VALUE="6" >6</OPTION>
<OPTION VALUE="7" Selected>7</OPTION>
<OPTION VALUE="8" >8</OPTION>
<OPTION VALUE="9" >9</OPTION>
<OPTION VALUE="10" >10</OPTION>
<OPTION VALUE="11" >11</OPTION>
</SELECT>
In
</TD>
</TR>
<TR>
<TD Width = "100" Align = "Right" CLASS = "tdmain">
<NOBR>
Weight:
</NOBR>
</TD>
<TD Width = "150" CLASS = "tdmain">
<SELECT NAME = "weight" CLASS = "formcolor">
<OPTION VALUE="35" >35</OPTION>
<OPTION VALUE="36" >36</OPTION>
<OPTION VALUE="37" >37</OPTION>
<OPTION VALUE="38" >38</OPTION>
<OPTION VALUE="39" >39</OPTION>
<OPTION VALUE="40" >40</OPTION>
<OPTION VALUE="41" >41</OPTION>
<OPTION VALUE="42" >42</OPTION>
<OPTION VALUE="43" >43</OPTION>
<OPTION VALUE="44" >44</OPTION>
<OPTION VALUE="45" >45</OPTION>
<OPTION VALUE="46" >46</OPTION>
<OPTION VALUE="47" >47</OPTION>
<OPTION VALUE="48" >48</OPTION>
<OPTION VALUE="49" >49</OPTION>
<OPTION VALUE="50" >50</OPTION>
<OPTION VALUE="51" >51</OPTION>
<OPTION VALUE="52" >52</OPTION>
<OPTION VALUE="53" >53</OPTION>
<OPTION VALUE="54" >54</OPTION>
<OPTION VALUE="55" >55</OPTION>
<OPTION VALUE="56" >56</OPTION>
<OPTION VALUE="57" >57</OPTION>
<OPTION VALUE="58" >58</OPTION>
<OPTION VALUE="59" >59</OPTION>
<OPTION VALUE="60" >60</OPTION>
<OPTION VALUE="61" >61</OPTION>
<OPTION VALUE="62" >62</OPTION>
<OPTION VALUE="63" >63</OPTION>
<OPTION VALUE="64" >64</OPTION>
<OPTION VALUE="65" >65</OPTION>
<OPTION VALUE="66" >66</OPTION>
<OPTION VALUE="67" >67</OPTION>
<OPTION VALUE="68" >68</OPTION>
<OPTION VALUE="69" >69</OPTION>
<OPTION VALUE="70" >70</OPTION>
<OPTION VALUE="71" >71</OPTION>
<OPTION VALUE="72" >72</OPTION>
<OPTION VALUE="73" >73</OPTION>
<OPTION VALUE="74" >74</OPTION>
<OPTION VALUE="75" >75</OPTION>
<OPTION VALUE="76" >76</OPTION>
<OPTION VALUE="77" >77</OPTION>
<OPTION VALUE="78" >78</OPTION>
<OPTION VALUE="79" >79</OPTION>
<OPTION VALUE="80" >80</OPTION>
<OPTION VALUE="81" >81</OPTION>
<OPTION VALUE="82" >82</OPTION>
<OPTION VALUE="83" >83</OPTION>
<OPTION VALUE="84" >84</OPTION>
<OPTION VALUE="85" >85</OPTION>
<OPTION VALUE="86" >86</OPTION>
<OPTION VALUE="87" >87</OPTION>
<OPTION VALUE="88" >88</OPTION>
<OPTION VALUE="89" >89</OPTION>
<OPTION VALUE="90" >90</OPTION>
<OPTION VALUE="91" >91</OPTION>
<OPTION VALUE="92" >92</OPTION>
<OPTION VALUE="93" >93</OPTION>
<OPTION VALUE="94" >94</OPTION>
<OPTION VALUE="95" >95</OPTION>
<OPTION VALUE="96" >96</OPTION>
<OPTION VALUE="97" >97</OPTION>
<OPTION VALUE="98" >98</OPTION>
<OPTION VALUE="99" >99</OPTION>
<OPTION VALUE="100" >100</OPTION>
<OPTION VALUE="101" >101</OPTION>
<OPTION VALUE="102" >102</OPTION>
<OPTION VALUE="103" >103</OPTION>
<OPTION VALUE="104" >104</OPTION>
<OPTION VALUE="105" >105</OPTION>
<OPTION VALUE="106" >106</OPTION>
<OPTION VALUE="107" >107</OPTION>
<OPTION VALUE="108" >108</OPTION>
<OPTION VALUE="109" >109</OPTION>
<OPTION VALUE="110" >110</OPTION>
<OPTION VALUE="111" >111</OPTION>
<OPTION VALUE="112" >112</OPTION>
<OPTION VALUE="113" >113</OPTION>
<OPTION VALUE="114" >114</OPTION>
<OPTION VALUE="115" >115</OPTION>
<OPTION VALUE="116" >116</OPTION>
<OPTION VALUE="117" >117</OPTION>
<OPTION VALUE="118" >118</OPTION>
<OPTION VALUE="119" >119</OPTION>
<OPTION VALUE="120" >120</OPTION>
<OPTION VALUE="121" >121</OPTION>
<OPTION VALUE="122" >122</OPTION>
<OPTION VALUE="123" >123</OPTION>
<OPTION VALUE="124" >124</OPTION>
<OPTION VALUE="125" >125</OPTION>
<OPTION VALUE="126" >126</OPTION>
<OPTION VALUE="127" >127</OPTION>
<OPTION VALUE="128" >128</OPTION>
<OPTION VALUE="129" >129</OPTION>
<OPTION VALUE="130" >130</OPTION>
<OPTION VALUE="131" >131</OPTION>
<OPTION VALUE="132" >132</OPTION>
<OPTION VALUE="133" >133</OPTION>
<OPTION VALUE="134" >134</OPTION>
<OPTION VALUE="135" >135</OPTION>
<OPTION VALUE="136" >136</OPTION>
<OPTION VALUE="137" >137</OPTION>
<OPTION VALUE="138" >138</OPTION>
<OPTION VALUE="139" >139</OPTION>
<OPTION VALUE="140" >140</OPTION>
<OPTION VALUE="141" >141</OPTION>
<OPTION VALUE="142" >142</OPTION>
<OPTION VALUE="143" >143</OPTION>
<OPTION VALUE="144" >144</OPTION>
<OPTION VALUE="145" >145</OPTION>
<OPTION VALUE="146" >146</OPTION>
<OPTION VALUE="147" >147</OPTION>
<OPTION VALUE="148" >148</OPTION>
<OPTION VALUE="149" >149</OPTION>
<OPTION VALUE="150" Selected>150</OPTION>
<OPTION VALUE="151" >151</OPTION>
<OPTION VALUE="152" >152</OPTION>
<OPTION VALUE="153" >153</OPTION>
<OPTION VALUE="154" >154</OPTION>
<OPTION VALUE="155" >155</OPTION>
<OPTION VALUE="156" >156</OPTION>
<OPTION VALUE="157" >157</OPTION>
<OPTION VALUE="158" >158</OPTION>
<OPTION VALUE="159" >159</OPTION>
<OPTION VALUE="160" >160</OPTION>
<OPTION VALUE="161" >161</OPTION>
<OPTION VALUE="162" >162</OPTION>
<OPTION VALUE="163" >163</OPTION>
<OPTION VALUE="164" >164</OPTION>
<OPTION VALUE="165" >165</OPTION>
<OPTION VALUE="166" >166</OPTION>
<OPTION VALUE="167" >167</OPTION>
<OPTION VALUE="168" >168</OPTION>
<OPTION VALUE="169" >169</OPTION>
<OPTION VALUE="170" >170</OPTION>
<OPTION VALUE="171" >171</OPTION>
<OPTION VALUE="172" >172</OPTION>
<OPTION VALUE="173" >173</OPTION>
<OPTION VALUE="174" >174</OPTION>
<OPTION VALUE="175" >175</OPTION>
<OPTION VALUE="176" >176</OPTION>
<OPTION VALUE="177" >177</OPTION>
<OPTION VALUE="178" >178</OPTION>
<OPTION VALUE="179" >179</OPTION>
<OPTION VALUE="180" >180</OPTION>
<OPTION VALUE="181" >181</OPTION>
<OPTION VALUE="182" >182</OPTION>
<OPTION VALUE="183" >183</OPTION>
<OPTION VALUE="184" >184</OPTION>
<OPTION VALUE="185" >185</OPTION>
<OPTION VALUE="186" >186</OPTION>
<OPTION VALUE="187" >187</OPTION>
<OPTION VALUE="188" >188</OPTION>
<OPTION VALUE="189" >189</OPTION>
<OPTION VALUE="190" >190</OPTION>
<OPTION VALUE="191" >191</OPTION>
<OPTION VALUE="192" >192</OPTION>
<OPTION VALUE="193" >193</OPTION>
<OPTION VALUE="194" >194</OPTION>
<OPTION VALUE="195" >195</OPTION>
<OPTION VALUE="196" >196</OPTION>
<OPTION VALUE="197" >197</OPTION>
<OPTION VALUE="198" >198</OPTION>
<OPTION VALUE="199" >199</OPTION>
<OPTION VALUE="200" >200</OPTION>
<OPTION VALUE="201" >201</OPTION>
<OPTION VALUE="202" >202</OPTION>
<OPTION VALUE="203" >203</OPTION>
<OPTION VALUE="204" >204</OPTION>
<OPTION VALUE="205" >205</OPTION>
<OPTION VALUE="206" >206</OPTION>
<OPTION VALUE="207" >207</OPTION>
<OPTION VALUE="208" >208</OPTION>
<OPTION VALUE="209" >209</OPTION>
<OPTION VALUE="210" >210</OPTION>
<OPTION VALUE="211" >211</OPTION>
<OPTION VALUE="212" >212</OPTION>
<OPTION VALUE="213" >213</OPTION>
<OPTION VALUE="214" >214</OPTION>
<OPTION VALUE="215" >215</OPTION>
<OPTION VALUE="216" >216</OPTION>
<OPTION VALUE="217" >217</OPTION>
<OPTION VALUE="218" >218</OPTION>
<OPTION VALUE="219" >219</OPTION>
<OPTION VALUE="220" >220</OPTION>
<OPTION VALUE="221" >221</OPTION>
<OPTION VALUE="222" >222</OPTION>
<OPTION VALUE="223" >223</OPTION>
<OPTION VALUE="224" >224</OPTION>
<OPTION VALUE="225" >225</OPTION>
<OPTION VALUE="226" >226</OPTION>
<OPTION VALUE="227" >227</OPTION>
<OPTION VALUE="228" >228</OPTION>
<OPTION VALUE="229" >229</OPTION>
<OPTION VALUE="230" >230</OPTION>
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<OPTION VALUE="232" >232</OPTION>
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<OPTION VALUE="253" >253</OPTION>
<OPTION VALUE="254" >254</OPTION>
<OPTION VALUE="255" >255</OPTION>
<OPTION VALUE="256" >256</OPTION>
<OPTION VALUE="257" >257</OPTION>
<OPTION VALUE="258" >258</OPTION>
<OPTION VALUE="259" >259</OPTION>
<OPTION VALUE="260" >260</OPTION>
<OPTION VALUE="261" >261</OPTION>
<OPTION VALUE="262" >262</OPTION>
<OPTION VALUE="263" >263</OPTION>
<OPTION VALUE="264" >264</OPTION>
<OPTION VALUE="265" >265</OPTION>
<OPTION VALUE="266" >266</OPTION>
<OPTION VALUE="267" >267</OPTION>
<OPTION VALUE="268" >268</OPTION>
<OPTION VALUE="269" >269</OPTION>
<OPTION VALUE="270" >270</OPTION>
<OPTION VALUE="271" >271</OPTION>
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<OPTION VALUE="286" >286</OPTION>
<OPTION VALUE="287" >287</OPTION>
<OPTION VALUE="288" >288</OPTION>
<OPTION VALUE="289" >289</OPTION>
<OPTION VALUE="290" >290</OPTION>
<OPTION VALUE="291" >291</OPTION>
<OPTION VALUE="292" >292</OPTION>
<OPTION VALUE="293" >293</OPTION>
<OPTION VALUE="294" >294</OPTION>
<OPTION VALUE="295" >295</OPTION>
<OPTION VALUE="296" >296</OPTION>
<OPTION VALUE="297" >297</OPTION>
<OPTION VALUE="298" >298</OPTION>
<OPTION VALUE="299" >299</OPTION>
<OPTION VALUE="300" >300</OPTION>
<OPTION VALUE="301" >301</OPTION>
<OPTION VALUE="302" >302</OPTION>
<OPTION VALUE="303" >303</OPTION>
<OPTION VALUE="304" >304</OPTION>
<OPTION VALUE="305" >305</OPTION>
<OPTION VALUE="306" >306</OPTION>
<OPTION VALUE="307" >307</OPTION>
<OPTION VALUE="308" >308</OPTION>
<OPTION VALUE="309" >309</OPTION>
<OPTION VALUE="310" >310</OPTION>
<OPTION VALUE="311" >311</OPTION>
<OPTION VALUE="312" >312</OPTION>
<OPTION VALUE="313" >313</OPTION>
<OPTION VALUE="314" >314</OPTION>
<OPTION VALUE="315" >315</OPTION>
<OPTION VALUE="316" >316</OPTION>
<OPTION VALUE="317" >317</OPTION>
<OPTION VALUE="318" >318</OPTION>
<OPTION VALUE="319" >319</OPTION>
<OPTION VALUE="320" >320</OPTION>
<OPTION VALUE="321" >321</OPTION>
<OPTION VALUE="322" >322</OPTION>
<OPTION VALUE="323" >323</OPTION>
<OPTION VALUE="324" >324</OPTION>
<OPTION VALUE="325" >325</OPTION>
<OPTION VALUE="326" >326</OPTION>
<OPTION VALUE="327" >327</OPTION>
<OPTION VALUE="328" >328</OPTION>
<OPTION VALUE="329" >329</OPTION>
<OPTION VALUE="330" >330</OPTION>
<OPTION VALUE="331" >331</OPTION>
<OPTION VALUE="332" >332</OPTION>
<OPTION VALUE="333" >333</OPTION>
<OPTION VALUE="334" >334</OPTION>
<OPTION VALUE="335" >335</OPTION>
<OPTION VALUE="336" >336</OPTION>
<OPTION VALUE="337" >337</OPTION>
<OPTION VALUE="338" >338</OPTION>
<OPTION VALUE="339" >339</OPTION>
<OPTION VALUE="340" >340</OPTION>
<OPTION VALUE="341" >341</OPTION>
<OPTION VALUE="342" >342</OPTION>
<OPTION VALUE="343" >343</OPTION>
<OPTION VALUE="344" >344</OPTION>
<OPTION VALUE="345" >345</OPTION>
<OPTION VALUE="346" >346</OPTION>
<OPTION VALUE="347" >347</OPTION>
<OPTION VALUE="348" >348</OPTION>
<OPTION VALUE="349" >349</OPTION>
<OPTION VALUE="350" >350</OPTION>
</SELECT>
Lbs
</TD>
</TR>
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<b>References</b><br>
Fontaine KR, Redden DT, Wang C, Westfall AO, Allison DB. Years of life lost due to obesity.
JAMA. 2003 Jan 8;289(2):187-93.
Rogers RG, Powell-Griner E. Life expectancies of cigarette smokers and non-smokers in the United States. Soc Sci Med 1991;32 (10):1151-1159.
<br>
CIA World Factbook: Life expectancy
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The Death Clock - When Am I Going To Die?
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Optimistic
|
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| Smoking Status: |
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| **The Lethal Danger of Being Fat**
Excess weight has a dramatic impact on one's health. The BMI (body mass index) is a way to measure your disease risk based on your height to weight ratio. People with a BMI of 25 to 29 are considered overweight and those with a BMI of 30 or more are considered obese.
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**References**
Fontaine KR, Redden DT, Wang C, Westfall AO, Allison DB. Years of life lost due to obesity.
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Rogers RG, Powell-Griner E. Life expectancies of cigarette smokers and non-smokers in the United States. Soc Sci Med 1991;32 (10):1151-1159.
CIA World Factbook: Life expectancy
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<html>
<HEAD><TITLE>70s Children's TV</title></head>
<body>
<h1>
<A HREF="isis.jpg"><IMG SRC="isis_small.gif" ALIGN=MIDDLE ALT="[Isis]"></a>
70s Children's TV
<A HREF="kss.jpg"><IMG SRC="krofft_icon.gif" ALIGN=MIDDLE ALT="[Krofft]"></a>
</h1>
When I was a little kid I used to sit and watch TV with my tape
recorder running. Sometimes I would even narrate, to fill in the
details that wouldn't be preserved on audio tape (like the names of
all the songs that whiz by in those record offers!). Here are some of
my earliest and most precious audio treasures, plus a lot of
contributions from other 70s kids.<p>
<h2>Kids Shows and Cartoons</h2>
<ul>
<li><A HREF="http://dt.prohosting.com/70s/childtv/sesame.au"><IMG SRC="sesame.gif" ALT="[SESAME STREET]">
<cite>Sesame Street</cite> theme music</a>, off the <cite>Sesame
Street 2</cite> record
<li><A HREF="captk.au"><IMG SRC="tv1972.gif" ALT="[1972]"></a> Here's
the part of the theme song from <cite>Captain Kangaroo</cite> that I
didn't talk over on this tape.
<li><A HREF="http://dt.prohosting.com/70s/childtv/electric.au"><IMG SRC="elecco.gif" ALT="[THE ELECTRIC
COMPANY]"></a> Theme song from <cite>The Electric Company</cite>
(Heyyy Youuu Guyyyyyys!!!)
<li><IMG SRC="zoomgirl.gif" ALT="[ZOOM]">
Memories of the <cite>ZOOM</cite> TV show
<ul>
<LI><IMG SRC="zoomlogo.gif" ALT="[ZOOM]"> sounds...
<li><A HREF="http://dt.prohosting.com/70s/childtv/zoomsong.au"><IMG SRC="zoomtiny.gif"
ALT="[ZOOM]"></a> ZOOM Theme song
<li><A HREF="zoomfan.au"><IMG SRC="zoomtiny.gif"
ALT="[ZOOM]"></a> A little fanfare that gets played often
during the show.
<li><A HREF="zoomrag.au"><IMG SRC="zoomtiny.gif"
ALT="[ZOOM]"></a> Incredibly dumb kazoo song they played at
least five times per show.
<li><A HREF="zoomaddr.au"><IMG SRC="zoomtiny.gif"
ALT="[ZOOM]"></a> A girl on the show reading (unfortunately not
singing) their familiar postal address. (Box three five oh...)
<li><A HREF="zoomubby.au"><IMG SRC="zoomtiny.gif"
ALT="[ZOOM]"></a> The <cite>Ubby Dubby</cite> fugue. For true
ZOOM fans and neurotics only.
<li><A HREF="zoomname.au"><IMG SRC="zoomtiny.gif"
ALT="[ZOOM]"></a> Some of you wanted to know the names of the
ZOOM kids. Here's one cast, straight from the mouth of
another kid: me! (I read the names aloud as they appeared on
the screen at the end of the show.)
<li><IMG SRC="zoomlogo.gif"> images...
<li><A HREF="zoomnames.jpg"><IMG SRC="zoomtiny.gif"
ALT="[ZOOM]"></a>
A devoted ZOOM fan sent in this scan of a cast listing
from ZOOM, listing the kids' names and ages.
<li><A HREF="zoomall.jpg"><IMG SRC="zoomtiny.gif"
ALT="[ZOOM]"></a>
Here's a nice composite image of some of the ZOOM kids.
I think it's from one of the later years.
<li><A href="http://www.pbs.org/wgbh/zoom/">
<IMG SRC="zoomtiny.gif" ALT="[ZOOM]"></a>ZOOM is back on the
air (new shows). Visit the new ZOOM website here.
<li><a href="thanksdave.ra"><IMG SRC="zoomtiny.gif"
ALT="[ZOOM]"></a>Here is an adorable thank-you for these
sound clips, from a family of ZOOM fans, new and old.
(RealAudio format.)
</ul>
<li><A HREF="pbs.au"><IMG SRC="tv1972.gif" ALT="[1972]"></a>Brief
synthsizer selection played over <cite>PBS</cite> logo, often heard
after the above shows
<li><A HREF="http://dt.prohosting.com/70s/childtv/josie.au"><IMG SRC="tv1972.gif" ALT="[1972]"></a> Theme
song to <cite>Josie and the Pussycats</cite>
<li><A HREF="felix.au"><IMG SRC="tv1973.gif" ALT="[1973]"></a> Theme
song from <cite>Felix The Cat</cite>. Granted, this goes back way
before 1973, but that's when I made this tape.
<li><A HREF="runjoe.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a>
Here's a promo for <cite>Run, Joe, Run!</cite>, a show about a dog who
is relentlessly pursued for something he didn't do.
<li><A HREF="wheelie.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a>
Make way for <cite>Wheelie and the Chopper Bunch</cite>.
<li><A HREF="gilligan.au"><IMG SRC="tv1975.gif" ALT="[1975]"></a>
Theme song from the <em>cartoon</em> version of <cite>Gilligan's
Island</cite>
<li><A HREF="http://dt.prohosting.com/70s/childtv/shazam.au"><IMG SRC="tv1975.gif" ALT="[1975]"></a>
Introduction to the TV show <cite>SHAZAM!</cite> (You can hear my
Australian dad laughing at it, if you listen closely.)
<li><A HREF="isis.jpg"><IMG SRC="isis_small.gif" ALT="[ISIS]"></a>
<cite>ISIS</cite> was the feminine counterpart to <cite>SHAZAM</cite>.
<ul>
<li><A HREF="http://dt.prohosting.com/70s/childtv/isis_intro.au"><IMG SRC="isistiny.gif"
ALT="[ISIS]"></a> This introduction should sound familiar.
<li><A HREF="isis_mighty.au"><IMG SRC="isistiny.gif"
ALT="[ISIS]"></a> To turn into the Egyptian Godess, she
had to intone, "Oh, Mighty Isis!".
<li><A HREF="isis_outro.au"><IMG SRC="isistiny.gif"
ALT="[ISIS]"></a> Here's the outro music. To me, it's
very reminiscent of Charlie's Angels.
<li><A HREF="isisdoll.jpg"><IMG SRC="isisdoll.gif"
ALT="[ISIS]"></a> Also check out this picture of an
ISIS doll.
</ul>
<li>Think Pink! Here are three sound bites from the <cite>Pink Panther</cite>
cartoon (the later one, with dialogue).
<ul>
<li><A HREF="http://dt.prohosting.com/70s/childtv/pinkbeg.au"><IMG SRC="tv1976r.gif"
ALT="[1976r]"></a> Opening theme.
<li><A HREF="pinkbit.au"><IMG SRC="tv1976r.gif"
ALT="[1976r]"></a> A memorable bit, in which the Pink Panther
keeps crushing the inspector by opening the door onto him,
alternately from the left, from the right, then down.
<li><A HREF="pinkout.au"><IMG SRC="tv1976r.gif"
ALT="[1976r]"></a> Outro, with cute descriptions of other
shows.
</ul>
<li><A HREF="innews.ra"><IMG SRC="tv1976.gif" ALT="[1976]"></a>
Remember those brief <cite>In The News</cite> news magazines for kids?
Here's an entire one in <A
HREF="http://www.realaudio.com/">RealAudio</a> format, complete with a
commercial for the <cite>Marathon Bar</cite> in the middle. Today's
topic is Fast Food in School Lunches.
<li><A HREF="http://dt.prohosting.com/70s/childtv/cosby.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a>
<cite>Fat Albert and the Cosby Kids</cite>
<li><A HREF="fatout.au"><IMG SRC="tv1978.gif" ALT="[1978]"></a>
Here's an outro from <cite>Fat Albert</cite>, with a voiceover
promoting <cite>What's New, Mister Magoo</cite> and <cite>Space
Academy</cite>.
<li><A HREF="lympics.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a>
<cite>Scooby's All-Star Laff-A-Lympics</cite>
<li><A HREF="sbuggy.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a>
<cite>Speed Buggy</cite>
<li><A HREF="suprfrnd.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a>
<cite>Superfriends</cite>
<li><A HREF="wndrtwin.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a>
<cite>Wonder Twins</cite>
<li><A HREF="bigjohn.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a>
Theme song from <cite>Big John, Little John</cite>
<li><IMG SRC="tv.gif" ALT="[TV]">Remember <cite>The Banana
Splits</cite>? Here is the <A HREF="splits.au">opening</a> and <A
HREF="splitend.au">closing</a> theme music.
</ul>
<h2>Krofft Shows</h2>
Sid and Marty Krofft gave us some of the best known and best
remembered kids TV shows.<p>
<ul>
<li><A href="http://dt.prohosting.com/70s/childtv/pufnstuf.au"><img src="tv1972.gif" alt="[1972]"></a>
Who could forget <cite>H.R. Pufnstuf</cite>?
<li><A HREF="landlost.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a>
Here's a promo for <cite>Land Of The Lost</cite>.
<li><a href="http://dt.prohosting.com/70s/childtv/lotl.au"><img src="tv1974.gif" alt="[1974]"></a>
This is the theme music for <cite>Land of the Lost</cite>.
<li><A href="http://dt.prohosting.com/70s/childtv/lidsville.au"><img src="tv1974.gif" alt="[1974]"></a>
<cite>Lidsville</cite>
<li><A HREF="lidout.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a> This
is an outro for <cite>Lidsville</cite>, featuring different theme
music, and a voiceover promo for another (non-Krofft) show:
<cite>Wheelie and the Chopper Bunch</cite>.
<li><a href="krofft.au"><IMG SRC="tv1976.gif" ALT="[1976]"></a> The
original <cite>Krofft Supershow</cite> Theme (1976) (or see the <A
HREF="krofft.txt">lyrics</a>)
<li><A HREF="supashow.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a> The
revised <cite>Krofft Supershow</cite> Theme (1979)
<li><A HREF="mongo.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a> The
theme music to <cite>Magic Mongo</cite>
<li><A HREF="http://dt.prohosting.com/70s/childtv/dynagirl.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a>
Theme music to <cite>Elektrawoman and Dynagirl</cite>
<li><A HREF="wondrbug.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a>
<cite>Wonder Bug</cite> theme
<li><A HREF="drshrink.au"><IMG SRC="tvd.gif" ALT="[TV-DEREK]"></a>
<cite>Dr. Shrinker</cite>
<li><a href="http://dt.prohosting.com/70s/childtv/bfandwb.au"><img src="tv.gif" alt="[TV]"></a>
<cite>Bigfoot and Wildboy</cite>
<li><A href="bugaloos.au"><img src="tv.gif" alt="[TV]"></a>
<cite>Bugaloos</cite>
</ul>
<h2>Krofft Information</h2>
<ul>
<li><A HREF="krofft_facts.txt">Krofft Fact Sheet</a>, provided by <A
HREF="mailto:latouf@netcom.com">Larry Latouf</a> (Larry also contributed
this nice composite <A HREF="kss.jpg">Krofft Picture</a>.)
<li>Text file with info on <A HREF="pufnstuf.txt">H.R. Pufnstuf</A>,
courtesy of <A HREF="mailto:jolomo@netcom.com">jolomo@netcom.com</a>
<li><A HREF="http://livingisland.com/">Living Island</a>, the unofficial
Krofft site
</ul>
<p>
<h2>Commercials directed at kids</h2>
<ul>
<li><A HREF="digem.au"><IMG SRC="tv1972.gif" ALT="[1972]"></a>
<cite>Kellogg's Sugar Smacks</cite> ad ("Dig 'em!")
<li><A HREF="wildride.au"><IMG SRC="tv1972.gif" ALT="[1972]"></a> The
<cite>Wild Rider</cite> (by Marx)
<li><A HREF="floops.au"><IMG SRC="tv1972.gif" ALT="[1972]"></a>
<cite>Froot Loops</cite> commercial. This is a variation on the
classic "follow your nose".
<li><A HREF="playdoh.au"><IMG SRC="tv1972.gif" ALT="[1972]"></a> Ad
for <cite>Playdoh Fun Factory Jr.</cite>
<li><A HREF="grrreat.au"><IMG SRC="tv1972.gif" ALT="[1972]"></a>
<cite>Kellogg's Sugar Frosted Flakes</cite> ad, complete with good ole
Tony The Tiger.
<li><A HREF="superwhe.au"><IMG SRC="tv1973.gif" ALT="[1973]"></a>
<cite>The Two Speed Superwheel With High/Low Stick Shift</cite> (by
Marx!)
<li><A href="crayola.au"><img src="tv1973.gif" alt="[1973]"></a>
By request, here is a commercial boasting of all the colors available
from <cite>Crayola</cite>.
<li><A HREF="bicbnana.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a>
Charles Nelson Reilly puts in a fun plug for <cite>Bic Banana Ink
Crayons</cite>.
<li><A HREF="dusty.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a>
She's my <cite>Dusty</cite>, the action/fashion doll that comes with
the award/night set. She plays tennis and golf, and looks beautiful,
too.
<li><A HREF="themos.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a>
Get up and go with <cite>Cheerios</cite>, with Super
Stripes for your bike in specially-marked boxes.
<li><A HREF="knievel.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a>
Here's a memorable commercial for the <cite>Evel Knievel Shock
Absorbing Stunt Cycle</cite>. You can't miss that cool noise it makes
when you wind it up.
<li><A HREF="ultrachr.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a>
In case Evel wasn't enough for you, how about these <cite>SSP
Ultrachrome Racers</cite>?
<li><A HREF="honycomb.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a>
<cite>Honeycomb</cite>'s big, yeah yeah yeah. It's not small, no no
no!
<li><A HREF="scouts.au"><IMG SRC="tv1974.gif" ALT="[1974]"></a>
Here's some dolls I'll bet no one has anymore: <cite>Steve
Scout</cite> and <cite>Bob Scout</cite>, approved by the Boy Scouts of
America.
<li><a href="booberry.au"><img src="tv1974.gif" alt="[1974]"></a>
Everyone remembers <cite>Count Chocula</cite> and
<cite>Frankenberry</cite>, but <cite>Boo Berry</cite> was the most
lovable of all. I used to have a Boo Berry beach towel.
<li><A HREF="freakies.au"><IMG SRC="tv1975.gif" ALT="[1975]"></a>
Commercial for <cite>Freakies Cereal</cite>. We are the freakies!
Everyone still have your free Freaky Magnets? They're not free
anymore! Believe it or not, <a href="http://www.freakies.com/">The
Freakies Company</a> is alive and well and has a web site! They offer
T-shirts, videos, pictures for children to color and more.<p>
They also have nice lawyers:<p>
<h6>
The "Freakies" Song is the copyrighted property of The
Freakies Company and is used with permission. The Freakies
Company is not responsible for the content of this web site.
Any commercial use of this material, or any unauthorized
display, distribution, transmission or other use of this
material, is expressly prohibited.
</h6>
<li><A HREF="mcd1.au"><IMG SRC="tv1975.gif" ALT="[1975]"></a>
<cite>McDonalds</cite> commercial (Ronald goes to the moon to get
cheese for cheeseburgers)
<li><A HREF="mcd2.au"><IMG SRC="tv1975.gif" ALT="[1975]"></a> Another
<cite>McDonalds</cite> ad (Who's the McFriendliest fellow in town...)
<li><A HREF="funshine.au"><IMG SRC="tv1975.gif" ALT="[1975]"></a> A
mercifully short clip of the theme music from <cite>Funshine Saturday
On ABC</cite>. If you want no mercy, here's a
<a href="http://www.real.com/">RealAudio</a> clip of the
<a href="funshine.ram">whole song</a>.
<li><A HREF="bking.au"><IMG SRC="tv1975.gif" ALT="[1975]"></a>
This isn't the most memorable, but it's still a <cite>Burger King</cite>
commercial from the 1970s.
<li><a href="candy.au"><img src="tv1976.gif" alt="[1976]"></a> Here's
an adorable public service announcement to warn kids not to regard
pills as candy. Some cute little pill-puppets danced around and sang
in squeaky pill-voices, "This is serious: we can make you
delirious...". I think it was called, <cite>We're Not Candy</cite>.
<li><A HREF="charlie2.au"><IMG SRC="tv1976r.gif" ALT="[1976r]"></a>
How seventies can you get? Here's an ad for <cite>Charlies
Angels</cite> dolls.
<li><A HREF="bigwheel.au"><IMG SRC="tv1976r.gif" ALT="[1976r]"></a>
When you were little, the <cite>Big Wheel</cite> was your
<em>ride</em>!
<li><A HREF="gmachine.au"><IMG SRC="tv1976r.gif" ALT="[1976r]"></a>
For the bigger kids, the <cite>Green Machine</cite> was much cooler.
<li><A HREF="crazycow.au"><IMG SRC="tv1976r.gif" ALT="[1976r]"></a>
The Mad Cow phenomenon might have put <cite>Crazy Cow</cite> cereal
right out of business if it had happened 20 years earlier.
<li><A HREF="digem2.au"><IMG SRC="tv1976r.gif" ALT="[1976r]"></a>
Here's a later <cite>Sugar Smacks</cite> commercial, still with the
original frog voice.
<li><A HREF="dynabee.au"><IMG SRC="tv1976r.gif" ALT="[1976r]"></a>
Remember those little hand gyroscope exerciser thingies? Why?
<li><A HREF="kidalong.au"><IMG SRC="tv1976r.gif" ALT="[1976r]"></a>
Wanna drive yourself nuts? Play this commercial for
<cite>Kidalongs</cite> (made by Tomy) about 10 times in a row!
<li><A HREF="mcd3.au"><IMG SRC="tv1976r.gif" ALT="[1976r]"></a>
Here's a later variation on the "Who's the McFriendliest"
<cite>McDonalds</cite> commercial.
<li><A HREF="savepsa.au"><IMG SRC="tv1976r.gif" ALT="[1976r]"></a>
Here's a PSA (public service announcement) to suggest kids should save
their money.
<li><A HREF="chocula.au"><IMG SRC="tv1976m.gif" ALT="[1976m]"></a>
This is a memorable one for <cite>Frankenberry</cite> and <cite>Count
Chocula</cite>. Sorry, no mention of <cite>Boo Berry</cite> in this
one.
<li><A HREF="mrmouth.au"><IMG SRC="tv1976m.gif" ALT="[1976m]"></a>
Mr. Mouth, Mr. Mouth. You'll remember this one. It's for a game.
<li><A HREF="thataway.au"><IMG SRC="tv1976m.gif" ALT="[1976m]"></a> I
have a small child that disobeys me. But for those who want one in
doll form, try <cite>Baby Thataway</cite>.
<li><A HREF="twister.au"><IMG SRC="tv1976m.gif" ALT="[1976m]"></a>
Even if you were in the midst of a tricky game of
<cite>Twister</cite>, you could probably sing this jingle better than
these guys did!
<li><A HREF="babyaliv.au"><IMG SRC="tv1976.gif" ALT="[1976]"></a>
Everyone should remember <cite>Baby Alive</cite>, the doll that drinks
and eats.
<li><A HREF="cookiec.au"><IMG SRC="tv1976.gif" ALT="[1976]"></a>
Cookies for breakfast? Heavens, no. Unless it's my <cite>Cookie
Crisp</cite> cereal, you know.
<li><A HREF="tpunch.au"><IMG SRC="tv1976.gif" ALT="[1976]"></a>
<cite>Tropical Punch flavored Kool Aid</cite> was new at one time.
Remember, kids? Oh yeeeaaaaaaaaaaaaaaaaaaaaah!
<li><a href="mcd4.au"><img src="tv1976.gif" alt="[1976]"></a> I
haven't heard the <cite>McDonalds Goblins</cite> sing in a long time.
Now, thanks to -DeeT's virtual drug, you can hear them, too!
<li><a href="mcdland.au"><img src="tv1976.gif" alt="[1976]"></a>
Here's another nostalgic <cite>McDonalds</cite> ad. The lyrical hook
says, "Everybody's headin' for McDonaldland".
<li><a href="http://dt.prohosting.com/70s/childtv/razzle.au"><img src="tv1976.gif" alt="[1976]"></a>
Here's a nice juicy long clip from the intro of the <cite>Hudson
Brothers Razzle Dazzle Show</cite>. Remember Ron Hull and his emu?
<li><a href="razzle_end.au"><img src="tv1976.gif" alt="[1976]"></a>
Ending music from the <cite>Hudson Brothers Razzle Dazzle Show</cite>.
<li><A HREF="dynamint.au"><IMG SRC="tv1978.gif" ALT="[1978]"></a>
Shake up your mouth, with <cite>Dentyne Dynamints</cite>.
<li><A HREF="reeses.au"><IMG SRC="tv1978.gif" ALT="[1978]"></a>
Hey! You got your peanut butter in my
chocolate... <cite>Reeses</cite>.
<li><img src="tv1978.gif" alt="[1978]"> The rock group
<cite>KISS</cite> was ahead of its time, not only musically but in
terms of merchandising. Here, kids can be the first on their block to
play with...
<ul>
<li><A href="kiss-radio.au"><img src="tv1978.gif"
alt="[1978]"></a> A <cite>KISS</cite> Radio
<li><A href="kiss-doll.au"><img src="tv1978.gif"
alt="[1978]"></a> <cite>KISS</cite> Dolls
<li><A href="kiss-your-face.au"><img src="tv1978.gif"
alt="[1978]"></a> <cite>KISS-Your-Face</cite> Make-up
</ul>
<li><IMG SRC="tv1979.gif" ALT="[1979]"> PSA TIME!!!!
<A HREF="mailto:SteveS012@aol.com">Steve</a> was
kind enough to send us some fun PSA spots that ran in the late 70s and
early 80s.
<ul>
<li><A HREF="psa4h.au"><IMG SRC="tv1979.gif" ALT="[1979]"></a>
Here's one on energy conservation from 4-H.
<li><A HREF="psabbb.au"><IMG SRC="tv1979.gif"
ALT="[1979]"></a>
"Abominable," a while fluffy snow monster thing with
a little black around its eyes, has some advice for the kids.
Created by the Better Business Bureau.
<li><A HREF="psanbc1.au"><IMG SRC="tv1979.gif" ALT="[1979]"></a>
This and the next two are from NBC.
They feature a goofy guy with dark curly hair
(Lenny Schultz, from the <cite>New Laugh-In</cite>
who tells us
that there's a <em>smart</em> way to watch TV.
<li><A HREF="psanbc2.au"><IMG SRC="tv1979.gif"
ALT="[1979]"></a>
There's a <em>smart</em> way to watch TV, part 2.
<li><A HREF="psanbc3.au"><IMG SRC="tv1979.gif"
ALT="[1979]"></a>
There's a <em>smart</em> way to watch TV, part 3.
</ul>
</ul>
<p>
Go
<A HREF="../70s.html"><IMG SRC="../back.gif" ALT="back" BORDER=0></a>
to
<A HREF="../70s.html">-DeeT's 70s Page</a>.
<p>
<ADDRESS><A HREF="mailto:70s@dt.prohosting.com">-DeeT
(70s@dt.prohosting.com)</A></ADDRESS>
</BODY>
</html>
|
70s Children's TV
#
[[Isis]](isis.jpg)
70s Children's TV
[[Krofft]](kss.jpg)
When I was a little kid I used to sit and watch TV with my tape
recorder running. Sometimes I would even narrate, to fill in the
details that wouldn't be preserved on audio tape (like the names of
all the songs that whiz by in those record offers!). Here are some of
my earliest and most precious audio treasures, plus a lot of
contributions from other 70s kids.
## Kids Shows and Cartoons
* [![[SESAME STREET]](sesame.gif)
Sesame Street theme music](http://dt.prohosting.com/70s/childtv/sesame.au), off the Sesame
Street 2 record
* [![[1972]](tv1972.gif)](captk.au) Here's
the part of the theme song from Captain Kangaroo that I
didn't talk over on this tape.
* [![[THE ELECTRIC
COMPANY]](elecco.gif)](http://dt.prohosting.com/70s/childtv/electric.au) Theme song from The Electric Company
(Heyyy Youuu Guyyyyyys!!!)
* ![[ZOOM]](zoomgirl.gif)
Memories of the ZOOM TV show
+ ![[ZOOM]](zoomlogo.gif) sounds...
+ [![[ZOOM]](zoomtiny.gif)](http://dt.prohosting.com/70s/childtv/zoomsong.au) ZOOM Theme song
+ [![[ZOOM]](zoomtiny.gif)](zoomfan.au) A little fanfare that gets played often
during the show.
+ [![[ZOOM]](zoomtiny.gif)](zoomrag.au) Incredibly dumb kazoo song they played at
least five times per show.
+ [![[ZOOM]](zoomtiny.gif)](zoomaddr.au) A girl on the show reading (unfortunately not
singing) their familiar postal address. (Box three five oh...)
+ [![[ZOOM]](zoomtiny.gif)](zoomubby.au) The Ubby Dubby fugue. For true
ZOOM fans and neurotics only.
+ [![[ZOOM]](zoomtiny.gif)](zoomname.au) Some of you wanted to know the names of the
ZOOM kids. Here's one cast, straight from the mouth of
another kid: me! (I read the names aloud as they appeared on
the screen at the end of the show.)
+ ![](zoomlogo.gif) images...
+ [![[ZOOM]](zoomtiny.gif)](zoomnames.jpg)
A devoted ZOOM fan sent in this scan of a cast listing
from ZOOM, listing the kids' names and ages.
+ [![[ZOOM]](zoomtiny.gif)](zoomall.jpg)
Here's a nice composite image of some of the ZOOM kids.
I think it's from one of the later years.
+ [![[ZOOM]](zoomtiny.gif)](http://www.pbs.org/wgbh/zoom/)ZOOM is back on the
air (new shows). Visit the new ZOOM website here.
+ [![[ZOOM]](zoomtiny.gif)](thanksdave.ra)Here is an adorable thank-you for these
sound clips, from a family of ZOOM fans, new and old.
(RealAudio format.)* [![[1972]](tv1972.gif)](pbs.au)Brief
synthsizer selection played over PBS logo, often heard
after the above shows
* [![[1972]](tv1972.gif)](http://dt.prohosting.com/70s/childtv/josie.au) Theme
song to Josie and the Pussycats* [![[1973]](tv1973.gif)](felix.au) Theme
song from Felix The Cat. Granted, this goes back way
before 1973, but that's when I made this tape.
* [![[1974]](tv1974.gif)](runjoe.au)
Here's a promo for Run, Joe, Run!, a show about a dog who
is relentlessly pursued for something he didn't do.
* [![[1974]](tv1974.gif)](wheelie.au)
Make way for Wheelie and the Chopper Bunch.
* [![[1975]](tv1975.gif)](gilligan.au)
Theme song from the *cartoon* version of Gilligan's
Island* [![[1975]](tv1975.gif)](http://dt.prohosting.com/70s/childtv/shazam.au)
Introduction to the TV show SHAZAM! (You can hear my
Australian dad laughing at it, if you listen closely.)
* [![[ISIS]](isis_small.gif)](isis.jpg)
ISIS was the feminine counterpart to SHAZAM.
+ [![[ISIS]](isistiny.gif)](http://dt.prohosting.com/70s/childtv/isis_intro.au) This introduction should sound familiar.
+ [![[ISIS]](isistiny.gif)](isis_mighty.au) To turn into the Egyptian Godess, she
had to intone, "Oh, Mighty Isis!".
+ [![[ISIS]](isistiny.gif)](isis_outro.au) Here's the outro music. To me, it's
very reminiscent of Charlie's Angels.
+ [![[ISIS]](isisdoll.gif)](isisdoll.jpg) Also check out this picture of an
ISIS doll.* Think Pink! Here are three sound bites from the Pink Panther
cartoon (the later one, with dialogue).
+ [![[1976r]](tv1976r.gif)](http://dt.prohosting.com/70s/childtv/pinkbeg.au) Opening theme.
+ [![[1976r]](tv1976r.gif)](pinkbit.au) A memorable bit, in which the Pink Panther
keeps crushing the inspector by opening the door onto him,
alternately from the left, from the right, then down.
+ [![[1976r]](tv1976r.gif)](pinkout.au) Outro, with cute descriptions of other
shows.* [![[1976]](tv1976.gif)](innews.ra)
Remember those brief In The News news magazines for kids?
Here's an entire one in [RealAudio](http://www.realaudio.com/) format, complete with a
commercial for the Marathon Bar in the middle. Today's
topic is Fast Food in School Lunches.
* [![[TV-DEREK]](tvd.gif)](http://dt.prohosting.com/70s/childtv/cosby.au)
Fat Albert and the Cosby Kids* [![[1978]](tv1978.gif)](fatout.au)
Here's an outro from Fat Albert, with a voiceover
promoting What's New, Mister Magoo and Space
Academy.
* [![[TV-DEREK]](tvd.gif)](lympics.au)
Scooby's All-Star Laff-A-Lympics* [![[TV-DEREK]](tvd.gif)](sbuggy.au)
Speed Buggy* [![[TV-DEREK]](tvd.gif)](suprfrnd.au)
Superfriends* [![[TV-DEREK]](tvd.gif)](wndrtwin.au)
Wonder Twins* [![[TV-DEREK]](tvd.gif)](bigjohn.au)
Theme song from Big John, Little John* ![[TV]](tv.gif)Remember The Banana
Splits? Here is the [opening](splits.au) and [closing](splitend.au) theme music.
## Krofft Shows
Sid and Marty Krofft gave us some of the best known and best
remembered kids TV shows.
* [![[1972]](tv1972.gif)](http://dt.prohosting.com/70s/childtv/pufnstuf.au)
Who could forget H.R. Pufnstuf?
* [![[1974]](tv1974.gif)](landlost.au)
Here's a promo for Land Of The Lost.
* [![[1974]](tv1974.gif)](http://dt.prohosting.com/70s/childtv/lotl.au)
This is the theme music for Land of the Lost.
* [![[1974]](tv1974.gif)](http://dt.prohosting.com/70s/childtv/lidsville.au)
Lidsville* [![[1974]](tv1974.gif)](lidout.au) This
is an outro for Lidsville, featuring different theme
music, and a voiceover promo for another (non-Krofft) show:
Wheelie and the Chopper Bunch.
* [![[1976]](tv1976.gif)](krofft.au) The
original Krofft Supershow Theme (1976) (or see the [lyrics](krofft.txt))
* [![[TV-DEREK]](tvd.gif)](supashow.au) The
revised Krofft Supershow Theme (1979)
* [![[TV-DEREK]](tvd.gif)](mongo.au) The
theme music to Magic Mongo* [![[TV-DEREK]](tvd.gif)](http://dt.prohosting.com/70s/childtv/dynagirl.au)
Theme music to Elektrawoman and Dynagirl* [![[TV-DEREK]](tvd.gif)](wondrbug.au)
Wonder Bug theme
* [![[TV-DEREK]](tvd.gif)](drshrink.au)
Dr. Shrinker* [![[TV]](tv.gif)](http://dt.prohosting.com/70s/childtv/bfandwb.au)
Bigfoot and Wildboy* [![[TV]](tv.gif)](bugaloos.au)
Bugaloos
## Krofft Information
* [Krofft Fact Sheet](krofft_facts.txt), provided by [Larry Latouf](mailto:latouf@netcom.com) (Larry also contributed
this nice composite [Krofft Picture](kss.jpg).)
* Text file with info on [H.R. Pufnstuf](pufnstuf.txt),
courtesy of [jolomo@netcom.com](mailto:jolomo@netcom.com)* [Living Island](http://livingisland.com/), the unofficial
Krofft site
## Commercials directed at kids
* [![[1972]](tv1972.gif)](digem.au)
Kellogg's Sugar Smacks ad ("Dig 'em!")
* [![[1972]](tv1972.gif)](wildride.au) The
Wild Rider (by Marx)
* [![[1972]](tv1972.gif)](floops.au)
Froot Loops commercial. This is a variation on the
classic "follow your nose".
* [![[1972]](tv1972.gif)](playdoh.au) Ad
for Playdoh Fun Factory Jr.* [![[1972]](tv1972.gif)](grrreat.au)
Kellogg's Sugar Frosted Flakes ad, complete with good ole
Tony The Tiger.
* [![[1973]](tv1973.gif)](superwhe.au)
The Two Speed Superwheel With High/Low Stick Shift (by
Marx!)
* [![[1973]](tv1973.gif)](crayola.au)
By request, here is a commercial boasting of all the colors available
from Crayola.
* [![[1974]](tv1974.gif)](bicbnana.au)
Charles Nelson Reilly puts in a fun plug for Bic Banana Ink
Crayons.
* [![[1974]](tv1974.gif)](dusty.au)
She's my Dusty, the action/fashion doll that comes with
the award/night set. She plays tennis and golf, and looks beautiful,
too.
* [![[1974]](tv1974.gif)](themos.au)
Get up and go with Cheerios, with Super
Stripes for your bike in specially-marked boxes.
* [![[1974]](tv1974.gif)](knievel.au)
Here's a memorable commercial for the Evel Knievel Shock
Absorbing Stunt Cycle. You can't miss that cool noise it makes
when you wind it up.
* [![[1974]](tv1974.gif)](ultrachr.au)
In case Evel wasn't enough for you, how about these SSP
Ultrachrome Racers?
* [![[1974]](tv1974.gif)](honycomb.au)
Honeycomb's big, yeah yeah yeah. It's not small, no no
no!
* [![[1974]](tv1974.gif)](scouts.au)
Here's some dolls I'll bet no one has anymore: Steve
Scout and Bob Scout, approved by the Boy Scouts of
America.
* [![[1974]](tv1974.gif)](booberry.au)
Everyone remembers Count Chocula and
Frankenberry, but Boo Berry was the most
lovable of all. I used to have a Boo Berry beach towel.
* [![[1975]](tv1975.gif)](freakies.au)
Commercial for Freakies Cereal. We are the freakies!
Everyone still have your free Freaky Magnets? They're not free
anymore! Believe it or not, [The
Freakies Company](http://www.freakies.com/) is alive and well and has a web site! They offer
T-shirts, videos, pictures for children to color and more.
They also have nice lawyers:
######
The "Freakies" Song is the copyrighted property of The
Freakies Company and is used with permission. The Freakies
Company is not responsible for the content of this web site.
Any commercial use of this material, or any unauthorized
display, distribution, transmission or other use of this
material, is expressly prohibited.
* [![[1975]](tv1975.gif)](mcd1.au)
McDonalds commercial (Ronald goes to the moon to get
cheese for cheeseburgers)
* [![[1975]](tv1975.gif)](mcd2.au) Another
McDonalds ad (Who's the McFriendliest fellow in town...)
* [![[1975]](tv1975.gif)](funshine.au) A
mercifully short clip of the theme music from Funshine Saturday
On ABC. If you want no mercy, here's a
[RealAudio](http://www.real.com/) clip of the
[whole song](funshine.ram).
* [![[1975]](tv1975.gif)](bking.au)
This isn't the most memorable, but it's still a Burger King
commercial from the 1970s.
* [![[1976]](tv1976.gif)](candy.au) Here's
an adorable public service announcement to warn kids not to regard
pills as candy. Some cute little pill-puppets danced around and sang
in squeaky pill-voices, "This is serious: we can make you
delirious...". I think it was called, We're Not Candy.
* [![[1976r]](tv1976r.gif)](charlie2.au)
How seventies can you get? Here's an ad for Charlies
Angels dolls.
* [![[1976r]](tv1976r.gif)](bigwheel.au)
When you were little, the Big Wheel was your
*ride*!
* [![[1976r]](tv1976r.gif)](gmachine.au)
For the bigger kids, the Green Machine was much cooler.
* [![[1976r]](tv1976r.gif)](crazycow.au)
The Mad Cow phenomenon might have put Crazy Cow cereal
right out of business if it had happened 20 years earlier.
* [![[1976r]](tv1976r.gif)](digem2.au)
Here's a later Sugar Smacks commercial, still with the
original frog voice.
* [![[1976r]](tv1976r.gif)](dynabee.au)
Remember those little hand gyroscope exerciser thingies? Why?
* [![[1976r]](tv1976r.gif)](kidalong.au)
Wanna drive yourself nuts? Play this commercial for
Kidalongs (made by Tomy) about 10 times in a row!
* [![[1976r]](tv1976r.gif)](mcd3.au)
Here's a later variation on the "Who's the McFriendliest"
McDonalds commercial.
* [![[1976r]](tv1976r.gif)](savepsa.au)
Here's a PSA (public service announcement) to suggest kids should save
their money.
* [![[1976m]](tv1976m.gif)](chocula.au)
This is a memorable one for Frankenberry and Count
Chocula. Sorry, no mention of Boo Berry in this
one.
* [![[1976m]](tv1976m.gif)](mrmouth.au)
Mr. Mouth, Mr. Mouth. You'll remember this one. It's for a game.
* [![[1976m]](tv1976m.gif)](thataway.au) I
have a small child that disobeys me. But for those who want one in
doll form, try Baby Thataway.
* [![[1976m]](tv1976m.gif)](twister.au)
Even if you were in the midst of a tricky game of
Twister, you could probably sing this jingle better than
these guys did!
* [![[1976]](tv1976.gif)](babyaliv.au)
Everyone should remember Baby Alive, the doll that drinks
and eats.
* [![[1976]](tv1976.gif)](cookiec.au)
Cookies for breakfast? Heavens, no. Unless it's my Cookie
Crisp cereal, you know.
* [![[1976]](tv1976.gif)](tpunch.au)
Tropical Punch flavored Kool Aid was new at one time.
Remember, kids? Oh yeeeaaaaaaaaaaaaaaaaaaaaah!
* [![[1976]](tv1976.gif)](mcd4.au) I
haven't heard the McDonalds Goblins sing in a long time.
Now, thanks to -DeeT's virtual drug, you can hear them, too!
* [![[1976]](tv1976.gif)](mcdland.au)
Here's another nostalgic McDonalds ad. The lyrical hook
says, "Everybody's headin' for McDonaldland".
* [![[1976]](tv1976.gif)](http://dt.prohosting.com/70s/childtv/razzle.au)
Here's a nice juicy long clip from the intro of the Hudson
Brothers Razzle Dazzle Show. Remember Ron Hull and his emu?
* [![[1976]](tv1976.gif)](razzle_end.au)
Ending music from the Hudson Brothers Razzle Dazzle Show.
* [![[1978]](tv1978.gif)](dynamint.au)
Shake up your mouth, with Dentyne Dynamints.
* [![[1978]](tv1978.gif)](reeses.au)
Hey! You got your peanut butter in my
chocolate... Reeses.
* ![[1978]](tv1978.gif) The rock group
KISS was ahead of its time, not only musically but in
terms of merchandising. Here, kids can be the first on their block to
play with...
+ [![[1978]](tv1978.gif)](kiss-radio.au) A KISS Radio
+ [![[1978]](tv1978.gif)](kiss-doll.au) KISS Dolls
+ [![[1978]](tv1978.gif)](kiss-your-face.au) KISS-Your-Face Make-up* ![[1979]](tv1979.gif) PSA TIME!!!!
[Steve](mailto:SteveS012@aol.com) was
kind enough to send us some fun PSA spots that ran in the late 70s and
early 80s.
+ [![[1979]](tv1979.gif)](psa4h.au)
Here's one on energy conservation from 4-H.
+ [![[1979]](tv1979.gif)](psabbb.au)
"Abominable," a while fluffy snow monster thing with
a little black around its eyes, has some advice for the kids.
Created by the Better Business Bureau.
+ [![[1979]](tv1979.gif)](psanbc1.au)
This and the next two are from NBC.
They feature a goofy guy with dark curly hair
(Lenny Schultz, from the New Laugh-In
who tells us
that there's a *smart* way to watch TV.
+ [![[1979]](tv1979.gif)](psanbc2.au)
There's a *smart* way to watch TV, part 2.
+ [![[1979]](tv1979.gif)](psanbc3.au)
There's a *smart* way to watch TV, part 3.
Go
[![back](../back.gif)](../70s.html)
to
[-DeeT's 70s Page](../70s.html).
[-DeeT
(70s@dt.prohosting.com)](mailto:70s@dt.prohosting.com)
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<title>MECHANISMS OF AGING</title>
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<CENTER> <H1>Mechanisms of Aging</H1> </CENTER>
<B>by Ben Best</B>
<H3>Please take the <i><b>short</b></i>
<A HREF="./LE_Survey.php" TARGET="_blank">Life Extension Values Clarification Survey</A></H3>
<P><B>Note: This monograph does NOT have a terminal copyright date — development is ongoing</B>
<CENTER> <H3><a name="contents"> CONTENTS: LINKS TO SECTIONS BY TOPIC </H3> </CENTER>
<OL TYPE=I>
<LI><a href="#define"> DEFINITION OF AGING </a>
<LI><a href="#symptoms"> SYMPTOMS OF AGING </a>
<LI><a href="#theories"> AN OVERVIEW OF AGING AND OF AGING THEORIES </a>
<LI><a href="#evolution"> EVOLUTION THEORY AND SPECIES-SPECIFIC AGING </a>
<LI><a href="#sex"> SEX AND AGING </a>
<LI><a href="#other"> AGING OF OTHER ORGAN SYSTEMS </a>
<LI><a href="#radical"> THE FREE RADICAL THEORY OF AGING </a>
<LI><a href="#mitochondria"> MITOCHONDRIA AND AGING </a>
<LI><a href="#glycation"> THE GLYCATION THEORY OF AGING </a>
<LI><a href="#protein"> PROTEINS DAMAGE AND MAINTENANCE IN AGING </a>
<LI><a href="#dna"> DNA DAMAGE AND DNA REPAIR </a>
<LI><a href="#telomeres"> TELOMERES AND AGING </a>
<LI><a href="#senescence"> CELLULAR SENESCENCE AND APOPTOSIS IN AGING </a>
<LI><a href="#progeria"> "ACCELERATED AGING" DISEASES (SEGMENTAL PROGERIA) </a>
<LI><a href="#longevity"> LONGEVITY GENES (FLIES & WORMS)</a>
<LI><a href="#longevity2"> LONGEVITY GENES (MAMMALS)</a>
<LI><a href="#silencing"> SIRTUINS AND DEACETYLASES IN AGING </a>
<LI><a href="#hormones"> HORMONES AND AGING </a>
<LI><a href="#immune"> THE IMMUNE SYSTEM AND AGING </a>
<LI><a href="#inflame"> INFLAMMATION AND AGING </a>
<LI><a href="#toxins"> ACCUMULATION OF TOXINS AND CHEMICAL GARBAGE </a>
<LI><a href="#cancer"> CANCER AND AGING </a>
<LI><a href="#biomarkers"> BIOMARKERS OF AGING </a>
<LI><a href="#cran"> CALORIC RESTRICTION WITH ADEQUATE NUTRITION (CRAN) </a>
<LI><a href="#methods">OTHER METHODS TO SLOW AGING</a>
<LI><a href="#rejuvenate">REGENERATIVE MEDICINE, STEM CELLS AND REJUVENATION</a>
<LI><a href="#conclusions"> AGING: CAUSE & CURE — SUMMARY & CONCLUSIONS </a>
<LI><a href="#references"> BOOK REFERENCES </a>
</OL>
<P>
<H3><a name="define">I. DEFINITION OF AGING </a></H3>
<P> <B>Aging</B> is a syndrome of changes that are deleterious, progressive,
universal and thus far irreversible. Aging damage occurs to molecules (DNA,
proteins, lipids), to cells and to organs. Diseases of old age (diseases which
increase in frequency with age, such as arthritis, osteoporosis, heart disease,
<A HREF="../health/cancer.html" TARGET="_blank">cancer</A>,
<A HREF="../lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's Disease</A>,
etc.) are often distinguished from aging
<B><I>per se</I></B>. But even if the aging process is distinct from
the diseases of aging, it is nonetheless true that the damage associated with
the aging process increases the probability that diseases of old age will occur.
<P> Some gerontologists prefer to use the word <B>senescence</B> because
"aging" implies that the passage of time necessarily results in
<B><I>deterioration</I></B>
(biological entropy) — which is certainly not true during the early,
<B><I>developmental</I></B>, time of life (before the age of 10 or 12 in humans).
I will retain the word "aging" because I
believe the association between aging & deterioration is universal
as adult years progress and because the distinction between aging & development is very
strongly established in conventional language. Also, shorter words make
for slightly faster reading.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="symptoms">II. SYMPTOMS OF AGING</a> </H3>
<P> One can catalog
changes that typically occur with age. For people of developed countries age
changes include: A loss of hearing ability, particularly for higher
frequencies. There is a decline in the ability to taste salt&bitter
(sweet&sour are much less affected). There is a reduction of the
thymus gland to 5−10% of its original mass by age 50.
Levels of antibodies increase with aging. One third
of men and half of women over 65 report some form of arthritis.
About half of those aged 65 have lost all teeth. The elderly require twice
as much insulin to achieve the glucose uptake of the young. There is
reduced sensitivity to growth factors & hormones due to fewer receptors
and dysfunctional post-receptor pathways. The temperature needed to
separate DNA strands increases with age. Weight declines after age 55
due to loss of lean tissue, water and bone (cell mass at age 70
is 36% of what it is at age 25). Body fat increases to age 60.
Muscle strength for men declines 30−40% from age 30 to age 80.
Reaction time declines 20% from age 20 to 60. Elderly people tend to
sleep more lightly, more frequently and for shorter periods — with a
reduction in rapid eye-movement (REM) sleep. Neurogenesis in the hippocampus
declines with age. Degree of saturation of fats drops by 26% in the brains
of old animals. Presbyopia (reduced ability to focus on close-up objects)
occurs in 42% of people aged 52−64, 73% of those 65−74
and 92% of those over age 75.
Most people over age 75 have cataracts. About half of those over 85 are
disabled (defined as the inability to use public transportation). Over
75% of people over 85 have 3−9 pathological conditions, and the cause of
death for these people is frequently unknown.
<P> Aging changes are frequently associated with an increase in
likelihood of mortality, but this is not necessarily the case. For
example, graying of hair is a symptom of aging, but graying does not increase
likelihood of mortality. Aging changes which are not associated with
a specific disease, but which are associated with a generalized increase
in mortality would qualify as <B>biomarkers</B> of aging — and would
distinguish <B>biological age</B> from <B>chronological age</B>.
Biomarkers would be better predictors of the increased likelihood
of mortality (independent of specific disease) than the passage of
time (chronological age). Cross-linking of collagen, insulin resistance
and lung expiration capacity have been proposed as candidates but, as
yet, no biomarkers of aging have been validated and universally accepted.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="theories">III. AN OVERVIEW OF AGING AND OF AGING THEORIES </a></H3>
<P> Many scientists have wondered whether a single cause (probably cellular
or hormonal) lies behind all aging phenomena — or whether aging is inherently
multi-faceted. Differences in lifespan between species raise critical
questions, in this regard. Why is a rodent old at 3 years, a horse old at
35 years and a human old at 80 years? Aren't the cells much the same? Why
is it that at age 3 about 30% of rodents have had cancer, whereas at age
85, about 30% of humans have had cancer? Some species (such as lobsters,
alligators and sharks) show few signs of aging. Cancer cells, stem
cells and human germ cells seem "immortal" when compared to other cells.
<img src="lifespan.gif" width="422" height="269" alt="[GRAPH OF SURVIVAL AGAINST AGE]" align="right">
<P> When discussing aging it is important
to distinguish two points on survival curves.
<B>Mean lifespan</B> (average lifespan) corresponds to the age at
which the horizontal line for 50% survival
intersects the survival curve. <B>Maximum
lifespan</B> corresponds to the age at which
the survival curves touch the age-axis (0%
survival) — and this represents the age
at which the oldest known member of the
species has died. (In animal studies, maximum lifespan is typically taken to be
the mean lifespan of the most long-lived 10%.) Curve A as shown is a
pure exponential decay curve. Curve B corresponds to the
survival of small animals, such as mice or squirrels in a natural
environment. Human survival was still close to
curve B in ancient Rome when average lifespan was 22 years, but by the
mid−1800s the typical North American lived to be 40 — more like curve C.
Today, people in the most developed countries have an average lifespan of about
80 — resembling curve D. Reduction of infant mortality has
accounted for most of the increased longevity, but since the 1960s mortality
rates among those over 80 years has been decreasing by about 1.5%
per year. Maximum lifespan for humans, however, has remained
about 115−120 all through known history. The longest documented human lifespan
has been for Frenchwoman Jean Calment who lived 122.3 years.
<P>Curing specific diseases such as heart
disease or cancer can do no more than further "square" the survival curve
(toward curve E), with no effect on maximum lifespan. Curing cancer would add about
2 years to human life, whereas eliminating heart disease would add 3 or 4 years.
<B>Mean lifespan</B> varies with susceptibility to disease, accident & homicide/suicide,
whereas <B>maximum lifespan</B> is determined by "rate of aging". In aging
research, maximum lifespan is regarded as a proxy for aging. Chemicals, calorie restriction
with adequate nutrition, or other interventions which increase maximum lifespan are said
to have slowed the aging process.
<P> If human beings were free of disease & senescence the only
causes of death would be accident, suicide & homicide. Under such
conditions it is estimated that from a population of one billion, a
12-year-old would have a median lifespan of 1,200 years and a maximum
lifespan of 25,000 years.
<P>In 1825 an English actuary named Benjamin Gompertz discovered that likelihood of
dying increases exponentially with age after maturity — an empirical observation that
has stood the test of time. A 35-year-old is twice as likely to die as a 25-year-old
and a 25-year-old is twice as likely to die as a 15-year-old. The exponential increase
does not continue past age 80 and death rate may even decline after age
110 [SCIENCE 280:855-860 (1998)]. (Medflies — Mediterranean fruit flies — show a
plateau of linear rather than exponential death rate when 20-25% of the population
remains). Similarly, the risk of getting
<A HREF="../lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's Disease</A>
doubles every 5 years past
the age of 60 — probably plateauing after age 90 (when over half the population
is already demented). Cancer rate increases exponentially with age, but also seems
to plateau in the very elderly. One explanation might be that subsets of the population
that are considerably more hardy due to genetics or behavior may remain after the more
heterogenous majority have died. Another explanation suggests the complete elimination
of the forces of natural selection at the oldest ages — which causes subsequent survival
to be completely the result of genetic "random drift" [PROCEEDINGS OF THE
NATIONAL ACADEMY OF SCIENCES (USA) 93:15249-15253 (1996)].
<A HREF="../lifeext/causes.html" TARGET="_blank">Causes of death</A> in middle-age tend to
be due to diseases affecting high-risk individuals (cancer, diabetes, hypertension, etc.),
whereas the elderly are more vulnerable to multiple pathologies due to vulnerability
of aging organs & tissues [JOURNALS OF GERONTOLOGY 58A(6):B495-B507 (2003)].
<P> Attempts to classify theories of aging have led to the two major
classifications <B> programmed aging </B> and <B> wear&tear aging</B>.
<B> Programmed aging </B> would be aging due to something inside an
organism's control mechanisms that forces elderliness & deterioration —
similar to the way genes program other life-stages such as cell
differentiation during embryological development or sexual maturation at
adolescence. By contrast aging due to <B> wear&tear </B> is not the
result of any specific controlling program, but is the effect of the sum
effect of many kinds of environmental assaults — ie, damage due to radiation,
chemical toxins, metal ions, free-radicals, hydrolysis, glycation,
disulfide-bond cross-linking, etc. Such damage can affect
genes, proteins, cell membranes, enzyme function, blood vessels, etc.
<P> When Pacific salmon have lived in the ocean for 2 or 3 years, they
make an arduous upstream journey against a raging riverswim until they find a place
suitable for spawning. After spawning, the adrenal gland releases massive amounts of
corticosteroids — leading to rapid deterioration. It would be costly for the species
to have salmon that could live another year and repeat the journey — or compete with the
offspring for food. Although this process is obviously
"programmed", it is inaccurate to describe it as
"aging". Programmed death, rather than programmed aging, is a
common phenomenon among animals that reproduce only once.
<P> Grazing animals show wear-and-tear to their teeth to the point where
they can no longer eat, and they die of starvation. Again, it stretches the
point to say the teeth are aging. The teeth of rabbits (like human
fingernails) continue to grow as wearing occurs — and in this sense are
"programmed" to compensate for "wear&tear". Why don't
grazing animals have teeth that continue to grow?
Human beings can replace tissue, capillaries and bone in wound-healing, yet
cannot regrow a severed limb the way a salamander can. Why isn't human
DNA "programmed" to re-grow kidney
or liver tissue as it ages? Planarians (flatworms) have a pool of stem
cells which can replace any of their fully differentiated cells. Programming
that compensates for wear & tear should be distinguished from programming
that causes deterioration.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="evolution">IV. EVOLUTION THEORY AND SPECIES-SPECIFIC AGING </a></H3>
<P> Russell Wallace, who with Charles Darwin discovered natural
selection, speculated that longevity much beyond the age of
procreation would be a disadvantage for a species. Parents
would threaten their children by competition for resources. This would
imply an evolutionary advantage to genetically programmed aging. The
programmed self-destruction with corticosteroids by Pacific salmon
after spawning — and whose decaying bodies provide nutrient for
their offspring — may be severe example indicating the possiblity
of programmed senescence. But as biologist Peter Medawar noted, there
is circular reasoning in claiming that senescence evolved so that
non-senescent individuals could more readily survive. If there were
no senescent, poorly-reproducing individuals, there would be no need
for replacement.
<P>If aging were the product of evolutionary forces, aging could
reasonably be expected to result from programming. But since most
animals in the wild die of accident, attack or disease
it seems questionable that evolutionary forces determine aging. Robins
in the wild, for example, have an estimated 12-year maximum lifespan
and a 40% chance of surviving any given year. With a (0.4)<SUP>12</SUP>
— or 1 in 60,000 — chance that a robin can avoid accident, attack or disease
for 12 years, there would seem to be little opportunity for natural selection
to play a role in the evolution of senescence. Against this argument is
evidence that early stages of senescence reduce the ability of an animal
to survive — thereby causing earlier selection against older animals.
<P> An alternative to the view that senescence is the product of evolution
compares genetic programming to the engineering of a fly-by satellite
designed to gather data about a planet. The engineering is focused on
ensuring that the satellite reaches its destination and performs its
data gathering/transmission when passing the planet. Beyond the planet
it is a matter of indifference to the engineers how long the satellite
continues to function — random decay occurs. Applying the analogy,
the satellite passing the planet is like an organism passing its
reproductive period. Once the objectives of reproduction & parenting
have been achieved the organism decays by random malfunction.
<P><TABLE BORDER = "2" ALIGN=LEFT>
<CAPTION ALIGN=TOP><B>Maximum lifespan of many animal species</B></CAPTION>
<TR><TD WIDTH="400">
<img src="MaxYears.jpg" width="600" height="300" alt="Maximum lifespan of many animal species">
</TR></TD>
</TABLE>
<BR CLEAR=all>
<p>
<p>The vast range of maximum lifespan differences between species
provides convincing evidence that longevity is genetically influenced.
An elephant lives about 10−20 times longer than
a mouse, yet both animals have roughly the same number of lifetime
heartbeats — the elephant at 30 per minute and the mouse at
300 per minute. Both species take about 200 million breaths
in a lifetime. And both species have a <B>metabolic potential</B> (total
kilocalories used per gram of body weight per lifetime) of about 200 kcal.
This figure is much the same for other mammals, but humans are exceptional
with a metabolic potential of 800 kcal. Brains use more energy than any other
human organ. (<B>Basal metabolic rate</B> for
humans is about 80 watts = 70 Calories per hour.) Birds
have a metabolic potential of 1,000 to 1,500 kcal.
<P> Gerontologists who compare the longevity of species explain
this discrepancy by saying that while body weight correlates well
with longevity, there is a better correlation with brain weight for primates.
For other species brain size may be more related to motor
function than to cognitive capacity.
<p>Flight, like brain weight, also confers a longevity advantage. Finches &
robins live about 3 times as long as rodents the same
size. Flying squirrels live twice as long as their close relatives
the chipmunks. Parrots have a maximum lifespan in excess of 90 years. The
Andean condor may be the most long-lived of any bird, but its maximum
lifespan has not been confirmed.
<p>Gross attributes of species typically associated with greater longevity are:
large size, ability to fly, brainy, a spiny or shelled encasement, and cold-blooded. All
but the last attribute reduce vulnerability to predators. Porcupines are the longest-lived
rodents. Naked mole rats, by living underground, are also
safer from predators and live significantly longer than similarly-sized rats.
All adaptations that afford protection from predators and other hazards justify
greater developmental resources to build a more durable
animal with a longer maximum lifespan.
<p>Opossums evolving on an island free of predators have been shown to have
substantially longer lifespans and smaller litters than opossums living on
the nearby mainland [JOURNAL OF ZOOLOGY; 229:695-708 (1993)]. Where competition
between individuals of a species for mates & resources is more important than
survival against predators and
other hazards, evolution causes more investment in making a more hardy & durable animal —
which includes having fewer offspring on each birthing (but more total offspring
over the lifetime) — with each offspring receiving more care and resources. Gene
survival can be better promoted (up to a point) by extending lifespan and reproductive
period of reproductively successful adults than by creating many more offspring,
a signficant number of whom will not survive to become reproductive adults.
<P>Large size also confers protection against predators and confers
an improved ability to escape dangerous environments. Metabolic rate decreases
proportionally with increases in body size, which allows larger animals to survive longer
when food & water are scarce. [For a sphere, surface area <b>S = 4πr<sup>2</sup></b>
and volume <b>V = (4/3)πr<sup>3</sup></b>, which means that <b>S</b>/<b>V</b> varies
inversely with <b>r</b> (radius). Because heat is generated in the volume and dissipates
in the surface area, relative dissipation decreases with an increase in radius because of
the decrease in <b>S</b>/<b>V</b>.] Large animals are better able to withstand extreme
temperatures because of greater body mass. Large animals and birds are more easily able
to travel long distances to find food or less harsh environments.
<p>Cold-blooded animals needn't expend energy to maintain body temperature and
therefore generate fewer free-radicals. Also, the rate of chemical reactions more than
doubles for each 10ºC increase in temperature. Cold-blooded animals may use one-tenth
as much energy as warm-blooded animals of the same body weight. The alligator, Galapagose
tortoise and lake sturgeon combine large size with cold-bloodedness. Turtles live
longer than other reptiles because of the shell which protects against predators.
With the combination of hard shell, large size and cold-bloodedness, it is not
surprising that the Galagose turtle is probably the most long-lived vertebrate.
Hard shell, cold-bloodedness and the ability to reduce metabolic rate allow
some <a href="http://en.wikipedia.org/wiki/Bivalvia" target="_blank">bivalves</a>
to live nearly four
centuries [<A HREF="http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=000221004"
TARGET="_blank">GERONTOLOGY; Philipp,EER; 56(1):55-65 (2010)</A>].
<P>A short-lived organism would waste metabolic
energy by over-investing in anti-oxidant or DNA-repair enzymes when the
energy could be spent on rapid growth and reproduction. When a species has fewer
predators, evolution invests fewer resources into speedy reproduction and more genetic
resources (DNA repair, etc.) into a longer reproductive period (longer life).
In the case of birds, the mitochondrial membranes contain more unsaturated fat making
them less vulnerable to lipid peroxidation. And the protein complexes of the respiratory
chain of mitochondria generate fewer free radicals in birds than in mammals.
It is conceivable that an animal with well-engineered cells could live many centuries.
Human germ cells have arguably lived for millions of years through an investment in
DNA-repair enzymes, antioxidant enzymes and telomerase.
<P>Evolutionary biologists are able to use artificial selection in the
laboratory experimentally (rather than passively studying natural
selection in the wild) to seek the evolutionary determinates of longevity.
Michael Rose at the University of California has shown that <B><I>Drosophila</I></B>
(fruit-flies) bred for 15 generations by disposing of eggs laid early in life and
only using eggs that were laid toward the
end of reproductive life achieved maximum lifespans 30% greater than that of controls.
The long-lived strains had increased levels of SOD, CAT and xanthine dehydrogenase
as well as increased levels of heat shock proteins conferring stress
resistance [JOURNALS OF GERONTOLOGY 55A(11):B552-B559 (2000)]. Hsp22 heat shock
protein expression was 2−10 times greater in the long-lived strains as compared to
controls. Transgenic <B><I>Drosophila</I></B> (ie, fruit flies with artificially altered
genes) with extra copies of hsp70 genes live nearly 8% longer than controls following
heat treatment [NATURE; Tatar,M; 390:30 (1997)].
<p>Dr. Rose has also observed the experimental increase in mortality associated
with aging ceases late in life [PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY; Rose;MR;
78(6):869-878 (2005)]. Although mortality rates remain very high in late-life, they
plateau. Studies of inbred <B><I>Drosophila</I></B> indicate that the plateauing
cannot be due to genetic variation. From his evolutionary biology perspective Dr. Rose
associates this phenomenon with a late-life end of the force of natural selection.
This would imply that senescence is genetically programmed and that studying
the genetics of the plateau could be the key to understanding the genetics of
longevity.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="sex">V. SEX AND AGING </a></H3>
<P>In nearly every culture on earth women outlive men — significantly
so in the oldest years. But the men who do survive to become
elderly are hardier than the women. A US National Institute of Aging study
showed that 44% of men over age 80 are "robust and independent"
compared with only 28% of women. And the percentage of surviving males
increases from 15% at age 100 to 40% at age 105 in the United
States.
<img src="fertile2.gif" width="450" height="364" alt="[Graph of
Fertility Decline]" align="right">
<P> If aging has been programmed
by evolutionary forces, sex could
be a very important contributor to
the program. The reproductive
organs of the human female exhibits
a rate of aging that is among
the most rapid of body systems. The
complete shutdown of female
fertility at menopause may be of
value in preventing the birth
of deformed children or death in
childbirth of a mother who has several
dependent children. For a species
with a lengthy parenting period, it
makes sense for fertility to cease
long before the debilities of
advancing age begin.
<B>Gonadotropin</B> hormones from
the pituitary gland are controlled by
<B>gonadotropin-releasing hormone</B>, a
10-amino-acid peptide originating
in neurons located in the <B>arcuate nucleus</B> of the hypothalamus. The two
gonadotropin hormones (<B>FSH</B> & <B>LH</B>) are the same for females as for males,
although their function is very different. Simplistically, FSH stimulates egg
production in females & sperm production in males, whereas LH stimulates
estrogen production in females & testosterone production in males.
<P> In fertile females <B>FSH</B>
(<B>Follicle-Stimulating Hormone</B>) accelerates the growth of 6−12 primary
follicles in the ovary each month — one of which may become a mature
ovum. The follicles secrete estrogens, the most powerful of which
is <B>estradiol</B>. A sudden increase in <B>LH</B> (<B>Luteinizing Hormone</B>) usually
triggers <B>ovulation</B> (follicle rupture with discharge of the ovum) and
the conversion of the follicle to the <B>corpus luteum</B> ("yellow body")
— which also secretes estrogen, but primarily secretes <B>progesterone</B>.
Progesterone stimulate the walls of the uterus to prepare it for implantation
of the fertilized ovum. If pregnancy occurs, progesterone inhibits
ovulation (by suppressing FSH & LH) and promotes uterine development
until the placenta becomes more mature. (Pro<B>gesterone</B> is so-named
because it promotes <B>gestation</B>, ie, the growth of offspring in the
womb).
<BR CLEAR=all>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=BOTTOM><B>Graph of Female Hormonal Cycles</B></CAPTION>
<TR><TD WIDTH="500">
<img src="cycles2.gif" width="465" height="389" alt="Female Hormonal Cycles">
</TR></TD>
</TABLE>
<P> Aside from their role in the
monthly cycle, estrogens are
responsible for the development
and maintenance of the female
sexual organs, cause the deposition
of fat in the breast&buttocks
(which contributes to the feminine
figure) and have a potent effect
on bone development.
<P> Menopause is the event in a
woman's life when her ovary
literally runs out of eggs. The loss of follicles to produce estradiol causes an end to
menstrual cycling and production of estrogen & progesterone by the ovary. At
age 30, a woman's period is normally
28−30 days, but by age 40
her period is typically
closer to 25 days and her rate of egg-loss has accelerated. Further shortening
(accompanied by periods when no
ovulation
occurs) eventually leads to menopause at an average
age of 50 (plus or minus 10 years). The menopausal woman often experiences
anxiety, irritability and fatigue. Beginning before menopause most women
experience "hot flashes", ie, 3 minute surges
of blood to the skin of the chest, shoulders & face leading to sudden
hotness & sweating. Hot flashes are associated with a pulsatile release
of LH from hypothalamic neurons associated with body temperature elevation.
Estrogen therapy eliminates hot flashes. The rate of loss of ovarian follicles
doubles around age 35, raising the suspicion that a hypothalamic mechanism
may be the ultimate cause of menopause [SCIENCE 273:67-70 (1996)].
<P> The most serious complications of menopause are osteoporosis and a
decline in cardiovascular health. The Framingham Heart Study demonstrated
that between ages 35 to 65 men have 10 times the incidence of heart attack
as women — probably because estrogen protects against heart disease.
Estrogen elevates HDL cholesterol and reduces LDL cholesterol in the
bloodstream.
<P> After menopause, nipples decrease in size and the surrounding alveolar
tissue shrinks. Erection of these tissues with external stimulation is more
difficult. Vaginal contractions during orgasm is reduced to 4−5 at
0.8-second intervals from 8−12 in young adults.
<P> The testes have been regarded as the source of maleness
at least since ancient Rome, where eunuchs & women were not
permitted to "testify" (<B>testis</B> is Latin for "witness"). In
the male, LH stimulates secretion of testosterone by the
interstitial cells of Leydig in the testes. FSH stimulates
spermatogenesis in the seminiferous tubules of the testes.
Testosterone promotes development of male sexual organs in the
foetus. At puberty testosterone stimulates hair growth on the
face & pubis, causes enlargement of the larynx to deepen the
voice, increases skin thickness, causes a 50% increase in muscle mass,
promotes bone growth, increases basal metabolism up to 15% and
increases red blood cell concentration.
<img src="testost.gif" width="347" height="296" alt="[Graph of Male Testosterone Decline]" align="right">
<P> There is no sudden "andropause"
event in males that is comparable to
the menopause event of females. Instead,
testosterone levels tend to decline
gradually with age. This decline occurs
most dramatically in those with cardiovascular disease or a predisposition
to adult-onset diabetes. Although sperm
count declines, fatherhood has been
verified for a male as old as 94.
Semen production declines in the prostate
as a man ages — and the smooth muscle is
replaced by overgrowing connective tissue
that enlarges the prostate,
blocks urine and can lead to cancer.
85% of men over age 50 have symptoms arising from <B>benign prostatic
hyperplasia</B> — a noncancerous overgrowth of prostate tissue possibly caused by
excessive expression of the anti-apoptosis protein <B>bcl−2</B> [HUMAN PATHOLOGY
27:668-675 (1996)]. In some tissues testosterone must
be converted to <B>dihydrotestosterone</B> (by
the enzyme <B>5−α reductase</B>) in order
to act. This occurs most notably in the
prostate gland, which produces semen (a
mixture of sugars, protein and water).
Dihydrotestosterone has also been
implicated in baldness. The European drug Permixon (an extract of the
saw palmetto berry) inhibits 5−α reductase, and is used to prevent
prostate hypertrophy and prostate cancer. The
<A HREF="http://www.lef.org" TARGET="_blank">Life Extension Foundation</A>
sells saw palmetto berry extracts as a dietary supplement for this purpose.
<P> Testosterone has been used in elderly men for "rejuvenation" — to restore
virility & muscle strength. Testosterone increases the risk of cardiovascular disease
— by increasing blood pressure, by lowering HDL cholesterol and by
elevating LDL cholesterol. These same dangerous side effects are also
seen in athletes who attempt to use androgens or other anabolic
steroids to improve athletic performance. Eunuchs reportedly live
longer, although there have been no controlled clinical trials to
prove this observation. Sterilization of a dog or cat (male or female)
adds a couple of years to its lifespan. Any reduction in sex hormones would be
expected to reduce cell proliferation and hence reduce the probability of cancer.
<P> Male libido peaks in mid-adolescence, and does not correlate
exactly with testosterone blood levels. In elderly men it may take
from 10 seconds to several minutes to get an erection, in contrast
to 3−5 seconds in young men. Contractions of the penile urethra during
orgasm is reduced to 1−2 contractions per 0.8-seconds from 3−4 in young
adults. Ejaculatory distance is reduced from 12−24 inches to 3−5 inches.
<P>[For more about sex and aging, see <A HREF="../health/SexHormR.html"
TARGET="_blank">Sex Hormone Replacement in Older Adults]</A>
<P><a href="#contents"> (return to contents)</a>
<H3><a name="other">VI. AGING OF OTHER ORGAN SYSTEMS </a></H3>
<P> Aging in the female reproductive system provides the best example of
programmed aging in mammals. For many other organs — particularly
the heart, brain, lung and kidney — specific disease states associated
with aging are of more significance than generalized deterioration. There
is wide variation in the health status of specific organs among the
elderly.
<P> Skin, lungs, muscles, blood vessels and organ-function in general
is adversely affected by protein cross-linking — which is increased in
diabetes. Because most of those 65 years of age have at least some
symptoms of subclinical diabetes and because most of the symptoms of aging
are accelerated in diabetes, diabetes figures strongly when the elderly
are described in terms of averages. Generalized reduction in blood flow
due to atherosclerosis also has an adverse effect on most organ systems
— some more than others. Both protein cross-linking and cardiovascular
deterioration are strongly influenced by genetics and environmental
influences (diet, smoking, etc.).
<p>With aging there is normally an age-related decrease in
<a href="../health/MacroNut.html#syndrome" target="_blank">insulin
sensitivity</a> as well as of resting metabolic rate per unit of fat-free
mass. These changes may not occur for those who maintain high levels of
aerobic exercise [<A HREF="http://jap.physiology.org/cgi/content/full/93/6/2105"
TARGET="_blank">JOURNAL OF APPLIED PHYSIOLOGY; Clevenger,CM; 93(6):2105-2111 (2002)</A>
and <A HREF="http://ajpendo.physiology.org/cgi/content/full/281/3/E633"
TARGET="_blank">AMERICAN JOURNAL OF PHYSIOLOGY; van Pelt,RE; 281(3):E633-E639
(2001)</A>]. A study of very long-lived persons (over age 95) did not show a
decline in resting metabolic
rate [<A HREF="http://jcem.endojournals.org/cgi/content/full/90/1/409"
TARGET="_blank">THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM; Rizzo,MR;
90(1):409-413 (2005)</A>], but another study of those over age 90 did show
reduced metabolic rate [JOURNAL OF GERONTOLOGY; Frisard,MI; 62A(7):752-759
(2007)]. Whether survival is due to this trait or whether the trait is a feature
of aging cannot be distinguished by cross-sectional studies.
<P> The kidney provides perhaps the most striking example of individual
variation in the effects of aging. On average, kidney weight declines
about 15% between ages 40 and 80. The kidney's filtering capacity
for the average 90-year-old is typically half what it is for the
average 20-year-old. But high blood pressure and diabetes are particularly
damaging to kidney function. A 20-year longitudinal study showed no
change at all among elderly men who had no health problems. If this
result can be extrapolated it would mean that within the human maximum
lifespan there is no significant kidney deterioration in the absence of disease
conditions. (For a discussion of the issue of whether dietary protein can
harm kidney function, see my essay
<A HREF="../health/kidney.html" TARGET="_blank">Does Excess Protein Cause Kidney Damage?</A>).
<P> Cardiovascular disease is the <a href="./causes.html" target="_blank">most
frequent cause of death</a> among those over age 85.
The left ventricle of the heart increases in size with age (hypertropy)
due to an increase in size of the heart muscle cells that must work
harder to pump blood through a circulatory system that has narrower
channels and reduced elasticity. Lipofuscin content of heart muscle
cells increases from about 1% in the young to over 5% in
the old. Arteries thicken with age such that about three-quarters of
elderly people have increased blood pressure (both systolic & diastolic).
But, stated conversely, about a quarter of elderly people do <B><I>not</I></B>
have elevated blood pressure. According to the Framingham Heart Study, systolic
blood pressure is a better predictor of mortality than diastolic blood pressure.
Hypertension is defined as a systolic blood pressure greater than 160mm Hg.
Hypertension is present in 5% of those aged 60 and nearly one quarter
of those aged 75-80. While heart attacks from ischemia account
for 43% of deaths for those 65−74 years of age, it accounts for only
8% of deaths for that age group in Japan (where death-rate from
stroke is much higher). (For more details concerning cardiovascular
disease, risk factors and prevention — see my essays
<A HREF="../health/cardio1.html" TARGET="_blank">Sudden Cardiovascular Death </A> and
<A HREF="../health/cardio2.html" TARGET="_blank">Prevention of Cardiovascular Disease</A>.)
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Aerobic capacity decline </B></CAPTION>
<TR><TD WIDTH="350">
<img src="./PeakVO2.jpg" width="350" height="300" alt="Aerobic capacity decline">
</TR></TD>
</TABLE>
<p>Aerobic capacity (<a href="http://en.wikipedia.org/wiki/VO2_max"
target="_blank">VO<sub>2</sub> max</a> — liters of oxygen consumed per
minute during peak exercise) declines increasingly steeply with age, and
declines more steeply in men than in women. Although exercise increases
aerobic capacity at any age, exercise does not prevent accelerated
decline [<A HREF="http://circ.ahajournals.org/cgi/content/full/112/5/674"
TARGET="_blank">CIRCULATION; Fleg,JL; 112(5):674-682 (2005)</A>].
<P> The claim that all people lose about 100,000 neurons per day has not
been supported by modern research. 2% of neurons are lost, on average,
between ages 20 and 90 (up to 40% of this loss in the frontal cortex).
Those over age 86 show an average 10% decline in brain weight from age 20.
Between age 30 and 90 brain volume declines an average of 14% in the
cerebral cortex, 35% in the hippocampus and 26% in cerebral
white matter. But <I><B>averaging</I></B> can be misleading, because the
elderly include many people with considerable dementia and others with
little or none. Nonetheless, a cross-sectional
<a href="http://en.wikipedia.org/wiki/Magnetic_resonance_imaging"
target="_blank">Magnetic Resonance Imaging</a> (MRI) study of healthy
volunteers showed age-related declines in the volume of gray matter in
association area (rather than sensory areas) of the cerebral cortex,
particularly in the prefrontal
cortex [<A HREF="http://cercor.oxfordjournals.org/cgi/reprint/7/3/268"
TARGET="_blank">CEREBRAL CORTEX; Raz,N; 7(3):268-282 (1997)</A>]. Dementias
are more common among the
elderly who develop cardiovascular disease. Dramatic reduction in cerebral
blood flow and in brain oxygen&glucose utilization is frequently seen after
the 8th decade of life. Although most dementias are due to
<A HREF="../lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's Disease</A>,
at least 20% of dementias are due to stroke(s).
<P> Skeletal muscles are "fast-twitch" or "slow-twitch".
<B>Fast-twitch muscles </B> ("white meat") can deliver much power
over short periods through energy from anaerobic (oxygen-free) phosphagen
(creatine phosphate) and glycogen/lactic-acid metabolism.
<B>Slow-twitch muscles </B> ("dark meat") provide
endurance with aerobic metabolism — using more mitochondria, more
myoglobin and more capillaries per square inch. Sprinters&jumpers have
more fast-twitch muscle, whereas marathoners&swimmers have more slow-twitch
muscle. Posture is maintained with slow-twitch muscles. Aging results in
greater loss of fast-twitch than slow-twitch muscle. Muscle fibers are
replaced by fat & connective-tissue. Mitochondria die. Exercise can
slow this deterioration because fast-twitch fibers atrophy due to loss of
the nerves that innervate them (a loss possibly due to disuse).
<P> Muscles in the iris of the eye atrophy, and pupil size reduces, with age
— increasing the need for illumination. The lens thickens and becomes
yellowed, reducing green-blue-violet discrimination. (Elderly painters
use less violet & dark blue because the colors look the same.)
<P> Collagen & elastin in tendons & ligaments become less resilient
and more fragmented as a person grows older, particularly due to
<A HREF="#glycation" TARGET="_blank">glycation</A>
(cross-linking of proteins by sugar). Articular cartilage becomes
frayed and the synovial fluid between joints becomes "thinner". Decline
in circulatory function contributes to this process. Glycation of collagen &
elastin is accelerated in diabetics due to high blood sugar.
<p>Hair graying accompanies aging regardless of gender or race. By 50 years
of age approximately 50% of people have 50% gray
hair [<a href="http://www.ncbi.nlm.nih.gov/pubmed/15036274"
target="_blank">MICRON; Van Neste,D; 35(3):193-200 (2004)</A>].
<p>Aging of skin is commonly divided into "chronological aging" and
"photoaging", with up to 80% of skin aging attributed to
photoaging in non-smokers. Photoaging is due to ultraviolet (UV) light,
which activates inflammatory cytokines & metalloprotein collagenases
as well as inducing free
radicals [<A HREF="http://archderm.ama-assn.org/cgi/content/full/138/11/1462"
TARGET="_blank">ARCHIVES OF DERMATOLOGY; Fisher,GJ; 138(11):1462-1479 (2002)</A>]. UV
radiation generates singlet oxygen which both activates metalloproteinases and
causes large scale deletions of mitochondrial
DNA [<A HREF="http://www.jbc.org/cgi/content/full/274/22/15345"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Berneburg,M;
274(22):15345-15349 (1999)</A>]. <A HREF="../nutrceut/phytochemicals.html#carotenoids"
TARGET="_blank">Carotenoids</A>, especially lycopene, are particularly effective
quenchers of singlet oxygen [ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS;
Di Mascio,P; 274(2):532-538 (1989)].
<P> Collagen & elastin also cross-link in skin, resulting in a loss
of elasticity. The protein <B>keratin</B> in fingernails is also a component
of the outer layer of skin (epidermis), which provides "water-proofing".
The epidermis thins with age, leading to wrinkles. Decreased secretion
by sweat glands increases vulnerability to heat stroke. When the
<B>melanocytes</B> (cells that produce the skin&hair-coloring substance
<B>melanin</B>)
associated with hair follicles cease functioning, hair turns white. Partial
reduction of melanocyte function results in hair that appears "gray".
Yet 90% of Caucasians show <B><I>increased</I></B> melanin in the form
of brownish spots on the back of their hands ("liver spots").
<p>Although heat waves tend to lead to increased mortality among the elderly,
those affected are generally persons with chronic disease conditions and unhealthy
lifestyles. There is little alteration of thermoregulation with age among the
normal elderly [<a href="http://jap.physiology.org/cgi/content/full/95/6/2598"
target="_blank">JOURNAL OF APPLIED PHYSIOLOGY; Kenney;LW; 95(6):2598-2603 (2003)</A>].
<P> Loss of flexibility of the proteins collagen & elastin in the lung
results in loss of elastic recoil. It becomes too difficult to fully
exhale, which reduces air exchange, reducing the capacity to do work.
Oxygen-to-tissue transfer rate is often halved by age 70.
<P> Bone is typically 25% water, 30% soft tissue (cells & blood
vessels) and 45% mineral deposits (mostly calcium). Most of the white
ash remaining after cremation is calcium, lead, zinc and potassium from
bone. Both men & women lose bone mass between the ages of 39 and 70
<B> (osteoporosis)</B>,
but post-menopausal women (who have reduce estrogen) lose bone mass at twice the rate as men.
Decreased growth hormone causes bone loss
in both sexes. The physical inactivity & malnutrition (especially
for calcium and Vitamins D & C) of so many elderly also worsens
bone loss. A reduction of one to three inches in height by age 80 is not unusual,
with women shrinking twice as much as men. Young bones have been compared to green tree
branches that can bend considerably before breaking — and upon breaking does so
with splintering. By contrast, old bone is like a dry stick that snaps
upon bending. 20% of hip fractures associated with osteoporosis are
fatal in the US.
<P> Joints in the bones of the inner ear calcify, contributing to
a loss in the ability to hear higher tones. Loss of sweat glands
in the ear causes earwax to become drier & crustier. Wax obstruction
reduces the ability to hear low frequencies.
<P> Aging reduces salivary secretion resulting in a drier mouth and
decreased protection from bacterial infection of the mouth. Gastric
juice volume is reduced 25% by age 60 and there is a 60% decline in
pepsin activity. But this does not noticeably affect digestion except
in the case of heavy meats. Absorption of <a href="../nutrceut/MiscSupp.html#VitD"
target="_blank">Vitamin D</a> (and, hence, calcium
absorption), <a href="../nutrceut/MiscSupp.html#B12"
target="_blank">Vitamin B<SUB>12</SUB></a>
(affected by reduced "intrinsic factor")
and folic acid all typically decline with age.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="radical">VII. THE FREE RADICAL THEORY OF AGING </a></H3>
<P> Atomic nuclei are surrounded by electron orbitals which contain a
maximum of two electrons, each having opposite spin. Hydrogen has one
outer orbital, but nitrogen, carbon and oxygen have 4 outer orbitals —
with a capacity for 8 electrons (an "octet"). Atoms are most
stable when they have filled orbitals. <B>Free radicals</B> are highly
reactive molecules or atoms that have an unpaired electron in an outer
orbital that is not contributing to molecular bonding ("free").
Atoms or small molecules that are free radicals tend to be
the most unstable, because larger molecules can have the capacity to
form resonance structures.
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Electron States of ROS</B></CAPTION>
<TR><TD WIDTH="500">
<img src="ROS.jpg" width="500" height="300" alt="Electon States of ROS">
</TR></TD>
<CAPTION ALIGN=BOTTOM><B>.</B> (dot) indicates free-radical extra electron</CAPTION>
</TABLE>
<P>Normal molecular oxygen (<B><SUP>3</SUP>O<SUB>2</SUB></B>, so-called <B>triplet
oxygen</B>) is a very unusual free-radical in that it has two unpaired electrons in outer
orbitals (a double radical).
<B>Pi−bonds</B> are bonds formed from overlapping p−orbitals. But for
<SUP>3</SUP>O<SUB>2</SUB>, two
pi−bonds are formed from two p−orbitals, each containing one electron. The two electrons
can have three possible arrangements: two "up"−spin (indicated by two up-arrows
in the diagram), two "down"−spin or one spin "up" and one spin
"down" — which makes <SUP>3</SUP>O<SUB>2</SUB> somewhat
stable. But by the addition of energy (22.5 kcal/mole), both electrons are
move into a single p−orbital, with the electrons having opposite spins
— giving <B>singlet
oxygen</B> (<B><SUP>1</SUP>O<SUB>2</SUB></B>).
<P>Although singlet oxygen is not a free-radical, the electrons are in an excited state and
can thus cause damaging reactions similar to those caused by oxygen free-radicals.
On the other hand, if an electron
is added to normal triplet oxygen, the new electron completes one orbital, leaving the
other orbital with an unpaired electron — resulting in a <B>superoxide
anion</B> (<B><SUP>.</SUP></B>O<SUB>2</SUB><B><SUP>−</SUP></B>), which is a
conventional, unitary free-radical. Singlet oxygen is attracted to double-bonds and can
react destructively with DNA & proteins. Singlet oxygen is especially reactive with the
amino acid histidine — resulting in enzyme denaturation. Singlet oxygen
oxidizes the guanine base of DNA to produce
8−OHdG/8−oxoG [<A HREF="http://www.jbc.org/cgi/content/full/275/51/40601"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Ravanat,J; 275(51):40601-50604 (2000)</A>].
Singlet oxygen from ultraviolet
light is believed to be the major contributor to "photoaging" of the
skin [<A HREF="http://www.jbc.org/cgi/content/full/274/22/15345"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Berneburg,M; 274(22):15345-15349 (1999)</A>].
<P> <B>Lewis structures</B> are structural chemical formulas depicting
outer-shell electrons. I use abbreviated Lewis structures showing
only relevant outer-shell electrons to explain free radicals — ie,
I show a single orbital containing paired or unpaired electrons. Because
an orbital containing one (unpaired) electron is not being complemented
with an electron of opposite spin, the electron is said to be in an
"unstable spin state" (another term for "free radical").
Thus, chemicals that react-with and stabilize free radicals are called
<B>spin-trapping</B> substances.
<P> Free radicals can damage nucleic
acids, proteins or lipids. For biological systems, oxygen
free radicals are the most important, in particular
<B>superoxide</B> (<B><SUP>.</SUP></B>O<SUB>2</SUB><B><SUP>−</SUP></B>),
<B>nitric oxide</B> (<B><SUP>.</SUP></B>NO)
and the <B>hydroxyl radical</B> (<B><SUP>.</SUP></B>OH).
About 0.3% of superoxide exists in protonated form
(HO<SUB>2</SUB><B><SUP>.</SUP></B>), which is more reactive
than superoxide itself. Because the protenated form of superoxide
is uncharged, it can penetrate cell membranes more effectively
than superoxide. Nitric oxide is a relatively unreactive free-radical
which has a half-life of a few seconds, normally reacting
quickly with oxygen (O<SUB>2</SUB>). But if nitric oxide encounters a
superoxide (<B><SUP>.</SUP></B>O<SUB>2</SUB><B><SUP>−</SUP></B>), it forms
peroxynitrite (ONOO<B><SUP>−</SUP></B>) which can decompose to
form a hydroxyl radical (<B><SUP>.</SUP></B>OH). Peroxynitrite, like
the hydroxyl radical, can react directly with proteins and other macromolecules
to produce carbonyls (aldehydes & ketones), cross-linking and lipid
peroxidation. Only 1−4% of the DNA single-strand breaks caused by
peroxynitrite are due to hydroxyl radical (indicating the minor effect decomposition
has on total DNA damage by peroxynitrite) [ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS;
Roussyn,I; 330(1):216-218 (1996)]. Although hydrogen peroxide (H<SUB>2</SUB>O<SUB>2</SUB>)
and hypochlorite (OCl<SUP>−</SUP> — the active ingredient in bleach)
are not themselves free radicals, these oxygen-containing molecules can
facilitate free-radical formation. Moreover, HOCl is estimated to be hundreds of
times more toxic than either hydrogen peroxide or
superoxide [PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Reiter,RJ;
917:376-386 (2000)].
<P>All of these highly reactive oxygen-containing molecules
(including singlet oxygen) are described as
<A HREF="http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/ROS.html"
TARGET="_blank"><B>Reactive Oxygen Species</B></A> (<B>ROS</B>).
ROS attack bases in nucleic acids, amino acid side chains in proteins and double-bonds
in unsaturated fatty acids — with the hydroxyl radical being the strongest
attacker. ROS attack of macromolecules is often called <B>oxidative stress</B>.
<B>Reactive Nitrogen Species</B> (<B>RNS</B>) also cause free radical damage. Peroxynitrite,
which does most of its damage to endothelial cells, is nearly as destructive as
the hydroxyl radical.
<P> In a neutral water solution about one per 10<SUP>−7</SUP> water molecules
will dissociate into two ions, a reaction that can be represented as:
<P> <B>H:O:H => :OH<SUP>−</SUP> + H<SUP>+</SUP></B>
<P>However, a water molecule subjected to ionizing radiation might dissociate
into two free radicals: a hydroxyl radical & a hydrogen atom. The reaction can be represented as:
<P> <B>H:O:H => <SUP>.</SUP>OH + <SUP>.</SUP>H</B>
<P>A superoxide ion (<B><SUP>.</SUP></B>O<SUB>2</SUB><B><SUP>−</SUP></B>) would result
from the addition of an electron to a normal oxygen
molecule (O<SUB>2</SUB>). A more complete Lewis structure of
oxygen-containing free-radical molecules (with oxygen & hydroxide
ion also illustrated for contrast) showing all outer shell electrons would be:
<P>
<center>
<img src="radicals.gif" width="465" height="98" alt="[ oxygen free-radical molecules ]" border="2">
</center>
<BR CLEAR=ALL>
<P>
<P> It would be more accurate to draw resonance structures, but the above
representations may be better for explanatory purposes.
<P> The weed-killing herbicide <a href="http://en.wikipedia.org/wiki/Paraquat" target="_blank">paraquat</a>
generates superoxide. Superoxide (<B><SUP>.</SUP></B>O<SUB>2</SUB><B><SUP>−</SUP></B>) ions are
generated in large numbers in the mitochondria. Two superoxide ions are enzymatically converted to
hydrogen peroxide (H<SUB>2</SUB>O<SUB>2</SUB>) by the enzyme superoxide dismutase:
<P> <B><SUP>.</SUP>O<SUB>2</SUB><SUP>−</SUP> +
<SUP>.</SUP>O<SUB>2</SUB><SUP>−</SUP> + 2H<SUP>+</SUP>
=> H<SUB>2</SUB>O<SUB>2</SUB> + O<SUB>2</SUB></B>
<P>The hydroxyl radical (<B><SUP>.</SUP></B>OH) is typically formed by oxidation of a reduced heavy metal
ion (Fe<SUP>++</SUP> or Cu<SUP>+</SUP>, usually) by the hydrogen peroxide:
<P> <B> Fe<SUP>++</SUP> + H<SUB>2</SUB>O<SUB>2</SUB>
=> Fe<SUP>+++</SUP> + <SUP>.</SUP>OH + :OH<SUP>−</SUP></B>
<P> The last reaction, known as the <B>Fenton Reaction</B>, may be the most
dangerous because it can occur in the cell nucleus and lead to DNA damage. The
oxidized iron (Fe<SUP>+++</SUP>) can then catalyze the <B>Haber-Weiss Reaction</B> between
superoxide and hydrogen peroxide to produce more hydroxyl radicals:
<P> <B><SUP>.</SUP>O<SUB>2</SUB><SUP>−</SUP> + H<SUB>2</SUB>O<SUB>2</SUB>
=> O<SUB>2</SUB> + <SUP>.</SUP>OH + :OH<SUP>−</SUP></B>
<P>At neutral pH the Haber-Weiss reaction occurs only to a negligible extent
when no metal ion is available to act as a catalyst. In the human body ascorbic acid is
normally beneficial rather than harmful because nearly all iron and copper ions are
tightly bound to carrier proteins (<B>transferrin</B> for iron and <B>cearuloplasmin</B>
for copper ions), but this is not the case in the Cerebral Spinal Fluid (CSF) or
where there is cellular breakdown due to <A HREF="../cryonics/ischemia.html"
TARGET="_blank">ischemic-reperfusion injury</A>. Bacteria are rich in iron, which
is why hydrogen peroxide from macrophages is such an effective bacterial killer.
<P>Metal ions can also react with ascorbate (Vitamin C) to produce singlet
oxygen (<SUP>1</SUP>O<SUB>2</SUB>) from normal triplet oxygen (<SUP>3</SUP>O<SUB>2</SUB>):
<P> <B> Cu<SUP>++</SUP> + ascorbate +
<SUP>3</SUP>O<SUB>2</SUB> => <SUP>1</SUP>O<SUB>2</SUB></B>
<p>Unlike iron, copper generates more singlet oxygen than hydroxyl radical upon
its reaction with hydrogen peroxide.
<P>Wherever it is produced, the hydroxyl radical is highly reactive and can cause
covalent cross-linking or free-radical propagation in a wide variety of
biological molecules. A cell's superoxide ions tend to be concentrated in the
mitochondria because they are too reactive to travel very far in an unaltered
state — and are much less frequently found in the nucleus than in
the cytoplasm. Similarly, hydroxyl radicals (which have a billionth-of-a-second
half-life) do not drift far from their site of formation. But hydrogen peroxide
molecules are more stable and can drift across the nuclear membrane into
the nucleus or near cell membranes where hydroxyl radicals can be generated when
heavy metal ions are encountered. Hydrogen peroxide can
damage proteins directly by the oxidation of <B>−SH</B> groups.
<P> The hydroxyl radical can react with molecules (LH)
in membranes to produce lipid molecule radicals
(<B>alkyl</B> = <B><SUP>.</SUP>L</B>)
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Peroxyl Radical from Alkyl Radical</B></CAPTION>
<TR><TD WIDTH="300">
<img src="peroxyl.jpg" width="300" height="300" alt="Peroxyl Radical from Alkyl Radical">
</TR></TD>
</TABLE>
<P><B> <SUP>.</SUP>OH + LH
=> <SUP>.</SUP>L + H<SUB>2</SUB>O</B>
<P>These lipid radicals can then react directly with oxygen (autoxidation)
in a self-propagating chain
reaction forming <A HREF="http://www.cyberlipid.org/perox/oxid0006.htm"
TARGET="_blank"><B>lipid peroxides</B></A> (lipid peroxyl radicals, lipid molecules
containing paired-oxygen groups −−OO−−):
<P><B> <SUP>.</SUP>L + O<SUB>2</SUB>
=> LOO<SUP>.</SUP>
<BR> LOO<SUP>.</SUP> + LH
=> LOOH + <SUP>.</SUP>L</B>
<P>The first reaction is about fifteen hundred times faster with singlet oxygen
(<SUP>1</SUP>O<SUB>2</SUB>) than with normal triplet oxygen (<SUP>3</SUP>O<SUB>2</SUB>).
Singlet oxygen is energetic enough, however, that it can react directly with the double
bonds of unsaturated fatty acids, without requiring a free radical intermediate.
<P> The lipid hydroperoxides (LOOH) can promote a Fenton reaction:
<P> <B> Fe<SUP>++</SUP> + LOOH + H<SUP>+</SUP>
=> Fe<SUP>+++</SUP> + <SUP>.</SUP>OL + H<SUB>2</SUB>O</B>
<P>The lipid alkoxyl radical
(<B>alkoxy</B> = <B>alkoxyl</B> = <B><SUP>.</SUP>OL</B>) is more reactive
and damaging than the lipid peroxide (peroxyl) radical
(<B>peroxy</B> = <B>peroxyl</B> = <B>LOO<SUP>.</SUP></B>).
Thus, by a small sequence of steps one free-radical (<B><SUP>.</SUP>L</B></B>) has
become two radicals (<B><SUP>.</SUP>L</B> and <B><SUP>.</SUP>OL</B>) — conditions for an
auto-amplifying chain reaction. Nonetheless, if two alkyl, alkoxyl or peroxyl radical
molecules collide they will nullify each other, but at the cost of creating a
cross-link (covalent bond) between the two lipids.
<TABLE BORDER = "2" ALIGN=RIGHT>
<TR><TD>
<TABLE BORDER=7 CELLSPACING=3 CELLPADDING=3>
<CAPTION ALIGN=TOP><B>Free Radical Half-Life at 37ºC</B></CAPTION>
<TR><TH><B>Radical</B></TH><TH><B>Symbol</B></TH><TH><B>Half-Life Time</B></TH></TR>
<TR><TD><B>Hydroxyl</B></TD><TD><B><SUP>.</SUP>OH</B></TD><TD><B>one nanosecond</B></TD></TR>
<TR><TD><B>Singlet Oxygen</B></TD><TD><B><SUP>1</SUP>O<SUB>2</SUB></B></TD><TD><B>one microsecond</B></TD></TR>
<TR><TD><B>Superoxide</B></TD><TD><B><SUP>.</SUP>O<SUB>2</SUB><SUP>−</SUP></B></TD><TD><B>one microsecond</B></TD></TR>
<TR><TD><B>Alkoxyl</B></TD><TD><B><SUP>.</SUP>OL</B></TD><TD><B>one microsecond</B></TD></TR>
<TR><TD><B>Peroxyl</B></TD><TD><B>LOO<SUP>.</SUP></B></TD><TD><B>ten milliseconds</B></TD></TR>
<TR><TD><B>Nitric Oxide</B></TD><TD><B><SUP>.</SUP>NO</B></TD><TD><B>few seconds</B></TD></TR>
</TABLE>
</TR></TD>
</TABLE>
<P>The reactivity of free radicals can be quantified by a table of half-life
(time taken for half of the remaining radicals to react) values at 37ºC (body
temperature). Short half-life corresponds to high reactivity. The one nanosecond half-life
of the hydroxyl radical indicates that it is so reactive that it reacts with the first
molecule it bumps into.
<P> Outside of the mitochondria, superoxide and hydrogen peroxide can be
generated on the endoplasmic reticulum through oxidation processes involving
cytochrome P−450 and NADPH−cytochrome c reductase. Abnormal
accumulation of normal metabolites such as lactate,
pyruvate, acetoacetyl−CoA and glyceraldehyde−3−phosphate can abnormally
increase levels of NADH oxidase & reduced flavoenzymes such as xanthine
oxidase. In the absence of sufficient electron acceptor substrates these
enzymes can directly transfer electrons to O<SUB>2</SUB> or Fe<SUP>+++</SUP>
to form superoxide or Fe<SUP>++</SUP>. Ascorbate forms
H<SUB>2</SUB>O<SUB>2</SUB> on autoxidation (direct combination with oxygen).
Both ascorbate & <B>mercaptans</B> (<B>thioalcohols</B>, ie, compounds having
"−SH" groups, where sulfur is substituted for the oxygen of alcohol) are
capable of reducing Fe<SUP>+++</SUP> & Cu<SUP>++</SUP> to Fe<SUP>++</SUP>
& Cu<SUP>+</SUP>, thereby promoting Fenton reactions.
<P> Lipid peroxidation of polyunsaturated fatty acids exposed to oxygen leads
to rancidity in foods. In living animal cells peroxidized membranes lose
their permeability, becoming rigid, reactive and nonfunctional. Lipid peroxidation
can produce singlet oxygen, hydroperoxides and lipid epoxides. In addition, many
damaging aldehydes are formed during lipid peroxidation, particularly
<B>M</B>alon<B>D</B>i<B>A</B>ldehyde (<B>MDA</B>, propanedial)
& <B>4−H</B>ydroxy<B>N</B>on<B>E</B>nal (<B>4−HNE</B>). MDA is a
major metabolite of <A HREF="../health/essfat.html" TARGET="_blank">
arachidonic acid (20:4)</A>[fatty acid with 20−carbons &
4 double-bonds]. MDA assays (notably <B>TBARS</B> —
<B>T</B>hio<B>B</B>arbituric <B>A</B>cid-<B>R</B>eacting <B>S</B>ubstances)
have been widely used as a measure of cell membrane lipid peroxidation.
4−HNE is also a product of <B>20:4</B> fatty acid autoxidation. 4−HNE reacts
with cellular components more strongly than MDA. 4−HNE reacts readily
with histidine residues, sulfhydryl groups and primary amino groups of
proteins [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC49119/"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Uchida,K; 89(10):4544-4548 (1992)</A>]. The fact that 4−HNE is
the most toxic known aldehyde produced by lipid peroxidation (much more
toxic than MDA) and yet is practically non-reactive with TBA (about
95% of TDA reactivity is due to MDA) points to the deficiency of
TBARS as a lipid peroxidation assay [ALCOHOL & ALCOHOLISM
20(2):161-173 (1985)]. F<sub>2</sub>−isoprotanes, produced by
oxidation of arachidonic acid, are the best biomarkers of lipid
peroxidation [<A HREF="http://www.fasebj.org/cgi/content/full/18/15/1791"
TARGET="_blank">FASEB JOURNAL; Montuschi,P; 18(15):1791-1800 (2004)</A>].
<BR CLEAR=all>
<P><center><TABLE BORDER = "2">
<CAPTION ALIGN=TOP><B>LIPID PEROXIDATION FORMING MDA</B></CAPTION>
<TR align="center"><TD WIDTH="700">
<img src="lipidmda.gif" width="700" height="216" alt="[ LIPID PEROXIDATION FORMING MDA]">
</TR></TD>
</TABLE></center>
<BR CLEAR=all>
<P> Unlike free-radicals, the aldehydes MDA, 4−HNE & other aldehydes are rather long-lived
and can drift far from membranes, damaging a wide variety of proteins, lipids & nucleic
acids [FREE RADICAL BIOLOGY AND MEDICINE 11:81-128 (1991)]. Such damaged molecules are
called Advanced Lipid peroxidation End-products (<b>ALE</b>, which can be as resistant
to degradation as AGEs [<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199390/"
target="_blank">BRITISH JOURNAL OF PHARMACOLOGY; Negre-Salvayre,A; 153(1):6-20 (2008)</A>].
4−HNE inactivates glucose−6−phosphate dehydrogenase, an enzyme required
for the formation of NADPH and for forming ribose residues for nucleic acid
biosynthesis. Aldehyde-bridge formation leads to the protein-protein cross-linking
associated with lipofuscin formation. Plasma levels of both MDA and 4−HNE rise
significantly with age [<a href="http://www.ncbi.nlm.nih.gov/pubmed/16551576"
target="_blank">FREE RADICAL RESEARCH; Gil,L; 40(5):495-505 (2006)</A>].
<P><A HREF="../health/essfat.html" TARGET="_blank">Polyunsaturated fatty acids</A> are more
vulnerable to free radical oxidation than any other macromolecules in the body — and the
sensitivity to free radical damage increases exponentially with the number of double bonds.
Studies of the liver lipids of mammals & a bird (pigeon) show an inverse relationship
between maximum lifespan and number of double bonds [JOURNAL OF GERONTOLOGY
55A(6):B286-B291 (2000)]. Nonetheless, brain phospholipid unsaturation does not vary much
between mammals, probably indicating the importance of unsaturated fatty acids for neural
function [COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY Part B 132:515-527 (2002)].
<P> Animal cells contain three important enzymes to deal with the superoxide
and hydrogen peroxide: <B> SuperOxide Dismutase</B> (<B>SOD</B>),
<B>glutathione peroxidase</B> and <B> CATalase</B> (<B>CAT</B>). A <B>dismutase</B>
is an enzyme that catalyzes the reaction of two identical molecules to produce molecules
in different oxidative states. In the absense of SOD, two superoxide ions can spontaneously
dismutate to produce hydrogen peroxide and singlet oxygen. SOD catalyzes a reaction
between two superoxide ions to produce hydrogen peroxide and triplet oxygen.
<P><B>Catalase</B>
catalyzes the formation of water & free oxygen from hydrogen peroxide.
CAT is present in membrane-limited organelles known as
<B>peroxisomes</B>. Peroxisomes contain enzymes that degrade amino
acids & fatty acids — producing hydrogen peroxide as a byproduct.
<P>
<img src="oxidate.gif" width="459" height="334" alt="[FREE-RADICAL OXIDATION CHAIN]"
align="right">
<P><A HREF="../nutrceut/NAC.html" TARGET="_blank">Glutathione</A>
is a tripeptide composed of the amino acids cysteine,
glycine and glutamic acid. Glutathione is the major antioxidant in the
non-lipid portion of cells (most of the cytoplasm). Glutathione exists in
a reduced form (<B>GSH</B>) and an oxidized form (<B>GSSG</B>). Reduced
glutathione hydrogen donation can neutralize a hydroxyl radical:
<P><B> GSH + <SUP>.</SUP>OH
—> <SUP>.</SUP>GS + H<SUB>2</SUB>O</B>
<P>and then oxidized glutathione radicals can neutralize each other:
<P><B> <SUP>.</SUP>GH + <SUP>.</SUP>GH
—> GSSG</B>
<p><B>Glutathione peroxidase</B>
neutralizes hydrogen peroxide by taking hydrogens from two GSH molecules — resulting in
two H<SUB>2</SUB>O and one GSSG.
The enzyme <B>glutathione reductase</B> then
regenerates GSH from GSSG with NADPH as a source of hydrogen.
<P> The elimination of hydrogen peroxide by glutathione can be written as
the reaction:
<P> <B> 2 GSH + H<SUB>2</SUB>O<SUB>2</SUB>
=> GSSG + 2 H<SUB>2</SUB>O </B>
<P>Long-lived transgenic fruit flies in which the enzyme which synthesizes GSH
was overexpressed showed a maximum lifespan extension of nearly
50% [<A HREF="http://www.jbc.org/cgi/content/full/280/45/37331"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Orr,WC; 280(45):37331-37338 (2005)</A>].
Glutathione levels generally decline with age [JOURNAL OF ANTI-AGING MEDICINE; Lang,CA;
4(2):137-144 (2001)], although no reduction of serum glutathione was seen in
elderly women deemed to be in excellent physical and mental
health [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/12486409"
TARGET="_blank">JOURNAL OF LABORATORY AND CLINICAL MEDICINE; Lang,CA; 140(6):413-417 (2002)</A>].
Free radicals act on lipids to
produce peroxides (−O−O− bonds) resulting in mutagenic epoxides and
insoluble & non-digestible age pigments such as lipofuscin. Glutathione
peroxidase/glutathione destroys fat peroxides in the same way it eliminates hydrogen peroxide:
<P> <B> 2 GSH + ROOH
=> GSSG + ROH + H<SUB>2</SUB>O </B>
<P> <B>Superoxide dismutase</B>(<B>SOD</B>) is the most abundant
anti-oxidant enzyme in animals. The liver, in particular, is very high
in SOD. Cellular concentration of SOD relative to metabolic
activity is a very good lifespan predictor of animal species. Most mammals
experience a lifetime energy expenditure of 200,000 calories per gram,
but humans have an amazing 800,000 calories per gram. Humans have the
highest levels of SOD — relative to metabolic rate — of all species studied.
Oxidative damage to DNA is ten times greater in rats than in humans.
Maximum lifespan correlates with lower rate of free-radical production
and higher rate of DNA repair [JOURNAL OF COMPARATIVE PHYSIOLOGY B
168(3):149-158 (1998)].
<P> The SOD molecule in the cytoplasm (<a href="http://en.wikipedia.org/wiki/SOD1"
target="_blank">SOD1</a>) and outside of cells (<a href="http://en.wikipedia.org/wiki/SOD3"
target="_blank">SOD3</a>) contains copper & zinc atoms
(<B>Cu/Zn−SOD</B>), whereas the SOD in mitochondria
(<a href="http://en.wikipedia.org/wiki/SOD2" target="_blank">SOD2</a>)
contains manganese (<B>Mn−SOD</B>).
<P> Superoxide dismutase without glutathione peroxidase or catalase (CAT) to
remove hydrogen peroxide is of little value. Insects lack glutathione
peroxidase, but experiments have been performed on fruit flies made transgenic
by having extra genes for SOD, CAT or both. The flies that were given
extra genes for SOD or CAT (but not both) had no more than a 10%
increase in mean lifespan, with no increase in maximum lifespan. But flies
that had extra genes for both SOD <B><I>and</I></B> CAT showed maximum
lifespan increase by as much as a third, while showing less protein oxidative
damage and better physical performance [SCIENCE 263:1128-1130 (1994)].
But criticisms that the above experiments had been performed on short-lived
strains of flies led to later experiments on long-lived strains of flies which
showed no lifespan extension for overexpression of Cu/Zn−SOD,
Mn−SOD, catalase and
thioredoxin [<A HREF="http://www.jbc.org/cgi/content/full/278/29/26418"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Orr,WC; 278(29):26418-26422
(2003)</A>].
<p>Nonetheless, an experiment using SOD/CAT mimetics in nematode worms increased
mean lifespan 44% [SCIENCE 289:1567-1569 (2000)]. Selective
inbreeding of bread-mold fungus resulted in strains with lifespans more
than 6 times longer than wild-type — a change that was shown to be due
to increased expression of antioxidant enzymes [FREE RADICAL BIOLOGY &
MEDICINE 8:355-361 (1990)]. Females express both more Mn−SOD and more
glutathione peroxidase than males, and this has been suggested to be the
reason females live longer than males in mammalian species [FEBS LETTERS;
Vina,J; 579(12):2541-2545 (2005)]. The maximum lifespan of transgenic mice has been
extended about 20% by overexpression of human catalase targeted to
mitochondria [SCIENCE; Schriner,SE; 308:1909-1911 (2005)]. Although
<a href="http://en.wikipedia.org/wiki/Naked_mole_rat" target="_blank">naked mole rats</a>
exhibit high levels of oxidative damage, these levels remain unchanged for over two
decades [<A HREF="http://www.pnas.org/content/106/9/3059.long"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Perez,VI; 106(9):3059-3064 (2009)</A>].
<P> Radiation produces the hydroxyl radical, but most of the oxygen
free radicals are byproducts of cell metabolism — particularly in the
mitochondria, the lysosomes and the peroxisomes. One of the reasons
these organelles are surrounded by membranes may be to protect the cell from
the free-radicals they generate. DNA may be sequestered in the nucleus,
in part, as additional protection against free radicals. Nonetheless, free
radicals contribute to DNA damage and mutation.
<P> In addition to enzymes, the animal cell uses many other chemicals to protect against
oxygen free-radicals. <A HREF="../nutrceut/VitaminE.html" TARGET="_blank">Vitamin E</A>
is the main free-radical trap in the (lipid) membranes. <B>Vitamin C</B> acts as an
anti-oxidant in the non-lipid ("watery") portions of cells, between cells and
in the bloodstream. <A HREF="../nutrceut/melatonin.html" TARGET="_blank">Melatonin</A>,
a hormone produced by the pineal gland in decreasing quantities with aging, efficiently
crosses membranes (including the nucleus) and is effective against hydroxyl radicals.
<P> <B>Uric acid</B> (which is mostly formed from purine degradation) protects
Vitamin C from oxidation by divalent ions and can act as an anti-oxidant.
Uric acid also protects against free-radical catalysis by binding iron. Humans have
higher levels of uric acid than monkeys and other mammals because humans lack the enzyme
uricase. But birds typically have twice the plasma uric acid concentration as humans. Birds
often live several times as long as comparably sized mammals despite over twice the metabolic
rate, 2−6 times the plasma glucose and a 3ºC higher body temperature.
<P> Mammals fed anti-oxidants show up to a 30% increase in average lifespan,
but no increase in maximum lifespan. Anti-oxidants are most valuable for
animals that are cancer-prone, or subjected to radiation or chemical toxins.
There are evidently homeostatic mechanisms in cells that govern the amount
of allowable anti-oxidant activity. For example, increased levels of
Vitamin E in the diet correlates with reduced levels of glutathione
peroxidase activity, and vice versa. Vitamin E was shown to increase
catalase in banana fruit-flies — with increasing doses of Vitamin E
extending fruit-fly lifespan up to a dose of 5 micrograms/mL, above which
increasing doses decreased lifespan [GERONTOLOGY 42:312-321 (1996)].
<P>(For more on anti-oxidants and anti-oxidant enzymes, see my essay
<A HREF="../nutrceut/AntiOxidants.html" TARGET="_blank">General Anti-Oxidant Actions</A>.)
<P><a href="#contents"> (return to contents)</a>
<H3><a name="mitochondria">VIII. MITOCHONDRIA AND AGING </a></H3>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Mitochondrion organelle</B></CAPTION>
<TR><TD WIDTH="500">
<img src="Mitochondrion.jpg" width="500" height="300"
alt="Mitochondrion organelle">
</TR></TD>
</TABLE>
<P> The <B>mitochondria</B> are capsule-shaped cellular organelles that generate energy
(<a href="http://en.wikipedia.org/wiki/Adenosine_triphosphate" target="_blank">ATP molecules</a>)
from aerobic (oxygen-utilizing) metabolism utilizing
respiratory chain and ATP synthase enzymes. Most animal cells contain between
a few hundred and a few thousand mitochondria. The most mitochondria are found in
the cells that are most metabolically active: neurons and muscle cells, where
mitochondria make up about 40% of cell volume. About 10% of the body
weight of a human adult is mitochondria.
<p>A mitochondrion has two membranes. The outer membrane contains small pores
(<a href="http://en.wikipedia.org/wiki/Porin_%28protein%29" target="_blank">porins</a>, also
known as Voltage-Dependent Anion Channels,<b>VDACs</b>)
that are freely permeable to ions and other molecules smaller than
10 <a href="http://en.wikipedia.org/wiki/Dalton_%28unit%29" target="_blank">kiloDaltons</a>
in size. The inner membrane is highly impermeable, even to
<a href="http://en.wikipedia.org/wiki/Proton" target="_blank">protons</a> (H<sup>+</sup>
ions). The proton gradient across the inner membrane is used by
<a href="http://en.wikipedia.org/wiki/ATP_synthase" target="_blank">ATP synthetase</a>
enzyme to generate ATP molecules. The region between
the outer membrane and the inner membrane is more positively charged
(<b>P−phase</b>) because of the higher proton concentration, whereas the
inside of the inner membrane is more negatively charged (<b>N−phase</b>, the
<a href="http://en.wikipedia.org/wiki/Matrix_%28biology%29#Mitochondrial_matrix"
target="_blank">matrix</a>). It is in the matrix that the
<a href="http://en.wikipedia.org/wiki/_acid_cycle" target="_blank">Krebs citric acid cycle</a>
occurs. There can be tens of thousands of respiratory chain and associated ATP synthase
molecules embedded in the inner membrane of a mitochondrion, especially in
metabolically active cells that have their inner membranes most highly folded into
<a href="http://en.wikipedia.org/wiki/Crista" target="_blank">cristae</a>
that increase surface area.
<p>The inner membrane contains a number of active molecule carriers, including a
phosphate (<b>P<sub>i</sub></b> = H<sub>2</sub>PO<sub>4</sub><sup>-</sup>)
carrier and the <b>Adenine Nucleotide Transporter</b> (ANT). The ANT imports
ADP molecules into the matrix for ATP synthesis in exchange for ATP molecules which
are exported for energy use throughout the cell (like portable batteries). The
<B>respiratory chain</B> ("electron transport chain") attached to
the inner wall of the inner membrane is composed of 4 protein complexes.
These protein complexes are identified as <b>Complex I, II, III and IV</b>.
Complex II consists of only four peptides, two of which comprise the Krebs citric
acid cycle protein
<a href="http://en.wikipedia.org/wiki/Succinate_-_coenzyme_Q_reductase" target="_blank">succinate dehydrogenase</a>,
and two of which anchor the complex to the inner mitochondrial membrane.
<p>Complex I and Complex II independently supply electrons to Complex III,
which supplies electrons to Complex IV. Soluble carriers are used to transport
electrons to and from Complex III. The soluble carrier transporting electrons
from Complex I & II to Complex III is
<A HREF="../nutrceut/CoEnzymeQ.html" TARGET="_blank"><b>Coenzyme Q</b></A>
(CoQ). The soluble carrier that transports electrons from Complex III to Complex IV is
<a href="http://en.wikipedia.org/wiki/Cytochrome_C" target="_blank"><b>cytochrome−c</b></a>.
For this reason Complex III is also known as
<b>cytochrome−c reductase</b> and Complex IV is also known as
<b>cytochrome−c oxidase</b>. Complex IV combines its electrons
(which are actually hydrogen atoms) with oxygen to form water. The energy released
by the oxidations in the respiratory chain are used to pump protons outside the
inner mitochondrial membrane.
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Protons pumped out of mitochondrial matrix</B></CAPTION>
<TR><TD WIDTH="300">
<img src="ETC_ATP.jpg" width="300" height="150"
alt="Protons pumped out of mitochondrial matrix">
</TR></TD>
<CAPTION ALIGN=BOTTOM><B>Re-entering protons drive "ATP turbine"</B></CAPTION>
</TABLE>
<P>The inner mitochondrial membrane is fairly impermeable to H<SUP>+</SUP> ions
("protons") and thus is able to function much like a hydroelectric dam.
Respiratory enzymes (Complex I, III & IV) pump protons out of the inner mitochondrial
matrix, building proton pressure outside the "dam" (the membrane). The proton
pressure ("proton-motive force") across the inner membrane is composed of two components:
a pH difference and an electrical potential (membrane potential), which is the
most important component. The pH difference is small, amounting to only about 0.5 pH
units. The <A HREF="../cryonics/viable.html#potential" TARGET="_blank">membrane potential</A>
of the mitochondrial membrane is about twice as great as that of a large nerve fiber, amounting
to over 200 milliVolts. <b>Complex V</b> (F<SUB>0</SUB>F<SUB>1</SUB>−ATP synthase)
is the "hydroelectric turbine" that utilizes the energy of the proton flow into the
matrix through the "turbine" to synthesize ATP. The ATP synthase (Complex V)
"rotary motor" is the smallest known natural nanomachine. It uses proton-motive
force to drive the endothermic reaction:
<P> <b>ADP + P<sub>i</sub> => ATP</b>
<p>The combined result of respiratory (oxidative) steps and the ATP-creation (phosphorylation of
ADP) step is called <B>oxidative phosphorylation</B>. Normally respiration (oxygen consumption)
and phosphorylation (ATP production) are tightly <B>coupled</B>, ie, the amount of ATP
produced corresponds to the amount of oxygen consumed — referred to as <B>state 3
respiration</B>. In the absence of ADP (eg, in a resting state), however, any respiration
that occurs will be due to "proton leak" through the inner mitochondrial membrane
rather than due to ATP production — referred to as <B>state 4 respiration</B>.
(State 1, state 2 and state 5 are experimental conditions of more
historical interest than metabolic interest.)
<p>In state 4 respiration protons flowing directly through the inner membrane rather
than through the "ATP turbine" (Complex V) produce heat energy rather than ATP
energy. <B>Uncoupling proteins</B> are weak acids that dissolve inner membrane lipids thereby
increasing the uncoupling of oxidation from phosphorylation. Uncoupling respiration from phosphorylation
to produce heat is useful for small rodents, naked newborn babies, and hibernating &
cold-acclimated animals, all of which contain "brown fat". Uncoupling is also useful
for fever production. <B>UCP1</B> is the UnCoupling Protein found in "brown fat",
fat which has been made brown by high concentrations of mitochondria. <B>UCP2</B> has broad tissue
distribution and seems to function in stress response, but its expression is less than 1%
of UCP1. <B>UCP3</B> is found in muscle and is regulated by thyroid hormone (T<SUB>3</SUB>).
UCP2 & UCP3 may cause uncoupling for the purpose of reducing mitochondrial superoxide
production [<a href="http://www.ncbi.nlm.nih.gov/pubmed/1793618"
target="_blank">FREE RADICAL BIOLOGY & MEDICINE; Echtay,KS; 43(10):1351-1371 (2007)</A>].
<P>The function of UCP1 is to generate
heat ("thermogenesis"). Claims have been made that UCP3 generates little
heat, but functions to reduce free radical damage by lowering protein gratient during
periods of high metabolic activity. Mice with higher UCP3 have shown higher metabolic
intensity (17% greater resting oxygen consumption) and 36% longer
lifespan [AGING CELL; Speakman,JR; 3(3):87-95 (2004)]. Proton leak has not been
shown to be a factor in CRAN (<A HREF="../calories/calories.html" TARGET="_blank">Caloric
Restriction with Adequate
Nutrition</A>) [<A HREF="http://ajpendo.physiology.org/cgi/content/full/286/1/E31"
TARGET="_blank">AMERICIAN JOURNAL OF PHYSIOLOGY; Ramsey,JJ; 286(1):E31-E40 (2004)</A>].
The fact that dieting-resistant obese subjects have been shown to have smaller amounts of
UCP3 [<A HREF="http://diabetes.diabetesjournals.org/cgi/content/full/51/8/2459"
TARGET="_blank">DIABETES; Harper,M; 51(8):2459-2466 (2002)</a>] would seem to indicate that
thermogenesis from UCP3 is not negligible.
<p>Compared to the heart & brain, mitochondria in the liver are more tightly coupled
and use oxygen more efficiently for ATP production. The heart & brain mitochondria
use more oxygen than liver mitochondria, but can produce ATP faster. Brain mitochondria
are more geared toward maintaining cell integrity, in contrast to heart mitochondria
which are more geared toward preserving cellular energy
state [<A HREF="http://ajpregu.physiology.org/cgi/content/full/274/5/R1376"
TARGET="_blank">AMERICAN JOURNAL OF PHYSIOLOGY; Cairns,CB; 274(5):R1376-R1383 (1998)</a>].
<P>Increasing insulin levels
associated with aging and type−2 diabetes stimulates nitric oxide synthetase resulting
in <A HREF="#radical" TARGET="_blank">peroxynitrite</A> [THE INTERNATIONAL JOURNAL
OF BIOCHEMISTRY & CELL BIOLOGY 34:1340-1354 (2002)]. Lipid peroxidation of the inner
mitochondrial membrane by peroxynitrite can increase proton leak independent of uncoupling
protein. Peroxynitrite can also degrade function of respiratory enzymes [JOURNAL OF
NEUROCHEMISTRY 70:2195-2202 (1998)] and inactivate mitochondrial superoxide dismutase (Mn−SOD)
enzyme [PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA) 93(21):11853-11858 (1996)].
<p>Mitochondria are the only
cellular organelles with their own DNA. (There is no other cellular DNA
outside the nucleus apart from the DNA of mitochondria.) Mitochondrial DNA
(<B>mtDNA</B>) in humans are circular strands of 16,569 nucleic acids that
code for 37 genes — 22 transfer RNAs, 2 ribosomal RNAs and 13 transmembrane
proteins. There are nearly 1,500 other gene products in mitochondria, which are
coded-for by nuclear DNA (<B>nDNA</B>). In contrast to nDNA, the mtDNA is
derived almost entirely from the mother. Each cell contains many mitochondria, but the total
mtDNA in a cell represents less than 1% of the amount of DNA found in the nucleus.
<BR CLEAR=all>
<P><TABLE BORDER = "2" ALIGN=LEFT>
<CAPTION ALIGN=TOP><B>Inner Membrane mtDNA-coded Proteins in Complex I, III, IV & V</B></CAPTION>
<TR><TD WIDTH="700">
<img src="mtDNA13p.jpg" width="700" height="250"
alt="Inner Membrane mtDNA-coded Proteins in Complex I, III, IV & V">
</TR></TD>
<CAPTION ALIGN=BOTTOM><B>Re-entering protons drive "ATP turbine"</B></CAPTION>
</TABLE>
<BR CLEAR=all>
<P>
<P> Each mitochondrion contains 2-to-12 identical copies of mitochondrial DNA
(2-to-12 circular strands).
Each mtDNA strand codes for 13 proteins, all of which are transmembrane subunits
of Complex I, III, IV or V. Of the 13 mtDNA proteins, 7 are in Complex I,
1 is in Complex III, 3 are in Complex IV and 2 are in Complex V.
A distinctive feature of the 13 proteins
coded-for by the mtDNA is that they are hydrophobic (not easily dissolved
in water), suggesting that it might be difficult to synthesize &
transport them in the watery cytoplasm. For this reason it has seemed improbable
that the mtDNA for these proteins could be moved to the nucleus where they
would be better protected & repaired. But one of the Complex V (ATPase)
mtDNA-coded proteins has been successfully synthesized in the nucleus and
utilized in the mitochondria for a mammalian cell [REJUVENATION RESEARCH;
Zullo,SJ; 8(1):18-28 (2005)] giving hope to the idea that all 13 mtDNA
proteins might eventually be moved to the nucleus. An alternate hypothesis, however,
claims that the mtDNA genes are of value in providing rapid local synthesis of proteins
required for oxidative phosphorylation. Oxidative stress due to insufficient oxidative
phosphorylation capability could signal mitochondrial transcription factors to induce
production of mtDNA-coded proteins that are then implanted into the inner membrane where
they attract the nDNA-coded proteins required for complete assembly of the
complexes [PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY; Allen,JF;
358(1429):19-38 (2003)].
<P> Complex I, which has 7 mtDNA-coded proteins (more than a quarter of
all the proteins in the Complex), ages most rapidly. Substantia nigra neurons have increased
susceptibility to Complex I defects — which may be responsible for Parkinson's
Disease [NEUROBIOLOGY OF AGING; Smigrodzki,R; 25:1273-1281 (2004)].
By contrast, Complex II (which has no mtDNA-coded proteins) and Complex III
(which has only one) are relatively unaffected by aging. Cytochrome−c oxidase (between
Complex III and Complex IV) activity declines with age, resulting in increased production
of superoxide and hydrogen peroxide. Diseases due to mutated mtDNA have the greatest
effect on cells producing the most energy — cells of brain and muscle — hence
mitochondrial diseases are often <B>encephalomyopathies</B> . A very common syndrome
of mitochondrial disease is <B>M</B>itochondria <B>E</B>ncephalomyopathy, <B>L</B>actic
<B>A</B>cidosis & <B>S</B>troke (<B>MELAS</B>). <B>Homoplasmy</B> describes the
original condition of all of a person's mtDNA being the same, but as mtDNA mutations occur
and the mutated mtDNA replicates, cells, tissues and even mitochondria can have a
mixture of mtDNA types, a condition known as <B>heteroplasmy</B>.
<P> An estimated 1−2% of oxygen used by mitochondria will normally "leak"
from the respiratory chain to form superoxide [JOURNAL OF NEUROCHEMISTRY
59:1609-1623 (1992) & JOURNAL OF INTERNAL MEDICINE 238:405-421 (1995)]. The pro-inflammatory
cytokine <B>Tumor Necrosis Factor−alpha</B> (<B>TNF−α</B>, associated with
<a href="../health/MacroNut.html#syndrome" target="_blank">the metabolic syndrome</a>)
induces increased free radical production from the respiratory
chain [<A HREF="http://www.nlm.nih.gov/medlineplus/print/ency/article/003646.htm"
TARGET="_blank">AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY; Corda,S;
24(6):762-768 (2001)</A>]. Aging is associated with decreased oxidative phosphorylation
coupling efficiency and increased superoxide production. Free radicals can damage the
mitochondrial inner membrane, creating a positive feedback-loop for increased
free-radical creation. The "viscious cycle" theory that free radical damage
to mitochondrial DNA leads to mitochondria that produce more superoxide has been
questioned. The most damaged mitochondria are consumed by lysosomes whereas the more
defective mitochondria (which produce less ATP as well as less superoxide) remain to
reproduce themselves [REJUVENATION RESEARCH; de Grey,A; 8(1):13-17 (2005)]. But the
efficiency of lysosomes to consume malfunctioning mitochondria declines with age,
resulting in more mitochondria producing higher levels of superoxide. Mitochondria of
older organisms are fewer in number, larger in size and less efficient (produce less
energy & more superoxide).
<P> <A HREF="../nutrceut/CoEnzymeQ.html" TARGET="_blank"><B>Coenzyme Q</B></A>
(CoQ, in humans CoQ<sub>10</sub>) is also known as <B>ubiquinone</B>,
so-called because it is "ubiquitous" (universally-found) in almost
all cellular organisms, with the exception of gram-positive bacteria and some
fungi. CoQ is an essential component of the mitochondrial respiratory chain.
From Complex I or Complex II dehydrogenase CoQ is reduced to
CoQH<SUB>2</SUB> and subsequently oxidized in two steps — first to
<B><SUP>.</SUP></B>CoQ<B><SUP>−</SUP></B> and then to CoQ. But
<B><SUP>.</SUP></B>CoQ<B><SUP>−</SUP></B> is unstable and can easily errantly
transfer an electron to an O<SUB>2</SUB> molecule resulting in superoxide
ion (<B><SUP>.</SUP></B>O<SUB>2</SUB><SUP>−</SUP>).
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B><SUP>.</SUP>O<SUB>2</SUB><SUP>−</SUP> from Complex III escapes Mitochondria</B></CAPTION>
<TR><TD WIDTH="400">
<img src="CompIIIO2.jpg" width="400" height="250"
alt="<SUP>.</SUP>O<SUB>2</SUB><SUP>−</SUP>from Complex III escapes Mitochondria">
</TR></TD>
</TABLE>
<P>Complex I has been believed to generate <B><SUP>.</SUP></B>O<SUB>2</SUB><SUP>−</SUP>
in one of the iron-sulfur clusters, which would go to the mitochondrial matrix
where it could be neutralized by Mn−SOD. Experiments on isolated mitochondria identified the
site of superoxide generation to be at the flavine mononucleotide moiety of
Complex I [<A HREF="http://www.jbc.org/cgi/content/full/279/6/4127"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Kudin,AP; 279(6):4127-4135 (2004)</A>],
but claims have been made that experiments on isolated mitochondria are
misleading [<A HREF="http://www.actabp.pl/pdf/1_2004/223.pdf"
TARGET="_blank">ACTA BIOCHEMICA POLONICA; Nohl,H; 51(1):223-229 (2004)</A>]. An experiment on
isolated synaptosomes indicated that Complex I inhibition
increases H<SUB>2</SUB>O<SUB>2</SUB>
production [<A HREF="http://www.jneurosci.org/cgi/content/full/24/36/7771"
TARGET="_new">THE JOURNAL OF NEUROSCIENCE; Tretter,L; 24(36):7771-7778 (2004)</A>]. Most of the
<B><SUP>.</SUP></B>O<SUB>2</SUB><SUP>−</SUP> generated from Complex III comes from
<B><SUP>.</SUP></B>CoQ<B><SUP>−</SUP></B>, with about half going to the matrix to be neutralized
and half floating toward the
cytoplasm [<A HREF="http://www.jbc.org/cgi/content/full/279/47/49064"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Muller,FL; 279(47):49064-49073 (2004)</A>]. Thus,
<B><SUP>.</SUP></B>O<SUB>2</SUB><SUP>−</SUP> from Complex I & III can cause
lipid peroxidation of the inner mitochondrial membrane and mtDNA damage, whereas
<B><SUP>.</SUP></B>O<SUB>2</SUB><SUP>−</SUP> from Complex III can damage the whole
cell, including nDNA. Membrane potentials below 140 mV (potential
resulting from the proton gradients across the inner mitochondrial membrane) are not
associated with <B><SUP>.</SUP></B>O<SUB>2</SUB><B><SUP>−</SUP></B>, but
above 140 mV <B><SUP>.</SUP></B>O<SUB>2</SUB><B><SUP>−</SUP></B> generation
increases exponentially with potential. Uncoupling proteins can be a device
for reducing proton pressure (membrane potential), thereby reducing superoxide production.
<BR CLEAR=all>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Voltage drops between Complexes</B></CAPTION>
<TR><TD WIDTH="600">
<img src="Volts_mt.jpg" width="600" height="400"
alt="Voltage drops between Complexes">
</TR></TD>
</TABLE>
<p>Higher voltage drops between energy states in the Complexes also result in greater
capacity for superoxide generation. This may account for the high superoxide production
associated with Complex I, which has a high voltage drop in transferring its
electrons to Complex III.
<p>Oxidative damage to particular mitochondrial proteins in the flight muscles of houseflies
has been identified as a <a href="#biomarkers" target="_blank">biomarker of aging</a> for
those insects. Specifically, adenine nucleotide transferase enzyme in mitochondrial
membranes [<A HREF="http://www.pnas.org/cgi/content/full/95/22/12896"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Yan,L;
95(22):12896-12901 (1998)</A>] and the
<a href="http://en.wikipedia.org/wiki/_acid_cycle" target="_blank">citric
acid cycle</a> enzyme
aconitase [<A HREF="http://www.pnas.org/cgi/content/full/94/21/11168"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Yan,L;
94(21):11168-11172 (1997)</A>] are particularly vulnerable to oxidative damage and are
used to identify the "physiological age" of houseflies. Aconitase also shows
the most significant age-related decline of any citric acid cycle enzyme in
mice [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835517/"
TARGET="_blank">MECHANISMS OF AGING AND DEVELOPMENT; Yarian,CS; 127(1):79-84
(2006)</A>]. Aconitase is readily oxidized by superoxide, a process that generates
hydroxyl radical [<A HREF="http://www.jbc.org/cgi/content/full/275/19/14064"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Vasquez-Vivar,J;
275(19):14064-14069 (2000)</A>].
<P>CoQ forms an important part of the antioxidant defense against these
superoxide radicals [BIOCHEMISTRY AND CELL BIOLOGY 70:390-403 (1992)].
The Mn−SOD (SuperOxide Dismutase) of mitochondria can be induced to higher
concentrations by oxidative stress (in contrast to the cytoplasmic
Cu/Zn−SOD which is constitutive rather than induced). Heart mitochondria
also contains catalase (which is confined to peroxisomes in most other
tissues) [BIOSCIENCE REPORTS 17(1):3-8 (1997)].
<P> Associated with aging is a decline in the amount of CoQ in organs.
A person 80 years old will typically have about half as much CoQ<sub>10</sub> in the
heart, lungs and spleen as a 20-year-old [LIPIDS 24(7):579-584 (1989)].
Declines in functional mitochondria &
CoQ<sub>10</sub> with age is most damaging to those organs that have the highest energy
demands per gram of tissue, namely: the heart, kidney, brain, liver and
skeletal muscle, in that order [JOURNAL OF INTERNAL MEDICINE 238:405-421
(1995)]. Neurons are the largest cells in the body and have the highest
metabolic demands, with 70% of ATP produced required to maintain the
sodium-potassium pump. Clinically, damage to brain and muscle tissue
are the first symptoms of mitochondrial disease. Mitochondria in the brain
tissue of
<A HREF="../lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's Disease</A>
patients is particularly damaged. Therapy has included the B−vitamins that
act as coenzymes in the respiratory chain (thiamine, riboflavin, niacinamide)
and CoQ<sub>10</sub> [ACTA NEUROLOGICA SCANDINAVIA 92:273-280 (1995)].
<P> mtDNA deletion mutations accumulate in post-mitotic cells with
age [BIOCHIMICA ET BIOPHYSICA ACTA 410:183-193 (1999)].
The "<B>mitochondrial theory of aging</B>" postulates that damage
to mtDNA and organelles by free radicals leads to loss of mitochondrial
function and loss of cellular energy (with loss of cellular function).
Mutations in mtDNA occur at 10-20 times the rate seen in nuclear DNA. A
significant portion of "photoaging" of the skin may be due to
mtDNA deletions from singlet oxygen induced by ultraviolet
light [<A HREF="http://www.jbc.org/cgi/content/full/274/22/15345"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Berneburg,M; 274(22):15345-15349
(1999)</A>]. Transgenic mice having high levels of mtDNA point mutations and
deletions are models of accelerated
aging [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/19656491"
TARGET="_blank">CELL METABOLISM; Edgar,D; 10(2):131-138 (2009)</A> and
<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815752/"
TARGET="_blank">AGING; Edgar,D; 1(12):1028-1032 (2009)</A>]. Unlike
nuclear DNA, mtDNA has no protective histone proteins. And DNA repair is less
efficient in mitochondria than in the nucleus. These factors account for the
more rapid aging seen with Complex I & III as compared to
Complex II & IV. Aging mitochondria become enlarged and, if they
can be engulfed by lysosomes, are resistant to degredation and contribute to
lipofuscin formation [<A HREF="http://content.febsjournal.org/cgi/content/full/269/8/1996"
TARGET="_blank">EUROPEAN JOURNAL OF BIOCHEMISTRY; Brunk,UT; 269(8):1996-2002 (2002)</A>].
<P>A comparison of
7 non-primate mammals (mouse, hamster, rat, guinea-pig, rabbit, pig and
cow) showed that the rate of mitochondrial superoxide and hydrogen peroxide
production in heart & kidney were inversely correlated with maximum life
span [FREE RADICAL BIOLOGY & MEDICINE 15:621-627 (1993)]. A similar study
of 8 non-primate mammals showed a direct correlation between maximum lifespan
and oxidative damage to mtDNA in heart & brain. There was a 4-fold
difference in levels of oxidative damage and a 13-fold difference in
longevity, supportive of the idea that mtDNA oxidative damage is but one
of several causes of
aging [<A HREF="http://www.fasebj.org/cgi/content/full/14/2/312"
TARGET="_blank">THE FASEB JOURNAL; Barja,G; 14(2):312-318 (2000)</A>].
<P> A comparison of the heart mitochondria in rats (4-year lifespan) and
pigeons (35-year lifespan) showed that pigeon mitochondria leak fewer
free-radicals than rat mitochondria, despite the fact that both animals have
similar metabolic rate and cardiac output. Pigeon heart mitochondria
(Complexes I & III) showed a 4.6% free radical
leak compared to a 16% free radical leak in rat heart mitochondria
[MECHANISMS OF AGING AND DEVELOPMENT 98(2):95-111 (1997)]. Hummingbirds
use thousands of calories in a day (more than most humans) and have
relatively long lifespans (the broad-tailed hummingbird <I>Selasphorus
platycerus</I> has a maximum lifespan in excess of 8 years). Birds have
less unsaturation (oxidizability) in their mitochondrial membranes and
have higher levels of small-molecule antioxidants, such as ascorbate
& uric acid. Even for mammals there is a direct relationship between mitochondrial
membrane saturation and maximum
lifespan [JOURNAL OF LIPID RESEARCH; Pamplona,R; 39(10):1989-1994 (1998)].
<P> Free-radicals from mitochondria result in damage to cellular protein,
lipids and DNA throughout the cell. This damage has been implicated as a
cause of aging. If the fatty acids entering the mitochondria for
energy-yielding oxidation have been peroxidized in the blood, this places
an additional burden on antioxidant defenses.
The greatest damage occurs in the mitochondria themselves,
including damage to the respiratory chain protein complexes (leading to higher
levels of superoxide production), damage to the mitochondrial membrane
(leading to membrane leakage of calcium ions and other substances) and
damage to mitochondrial DNA (leading to further damage to mitochondrial protein
complexes). An experiment in yeast that improved the accuracy of mitochondrial
protein synthesis demonstrated a 27% longer mean life
span [JOURNAL OF GERONTOLOGY 57A(1):B29-B36 (2002)].
<a name="MPTP"></a>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Mitochronrial Permaeability <br> Transition Port (MPTP)</B></CAPTION>
<TR><TD WIDTH="250">
<img src="MPTP.jpg" width="250" height="250"
alt="Mitochronrial Permaeability <br> Transition Port (MPTP)</">
</TR></TD>
</TABLE>
<p>Mitochondria play a key role in <b>apoptosis</b> ("cell suicide").
Release of cytochrome−c from mitochondria into the cytoplasm is the
event which initiates apoptotic cell destruction by caspase enzymes. Release
of cytochrome−c into the cytoplasm can occur either by a
Ca<sup>2+</sup>−dependent mechanism or a Ca<sup>2+</sup>−independent
mechanism. In the <b>Ca<sup>2+</sup>−dependent case</b> Ca<sup>2+</sup>
overload in the mitochondrion triggers opening of the Mitochondrial Permeability
Transition Pore (<b>MPTP</b>), which penetrates both the outer and
inner membranes making a channel between the mitochondrial matrix and the
cytosol outside the mitochondrion. The MPTP is a complex consisting of three
proteins, <b>VDAC</b> (porin) of the outer membrane, <b>ANT</b> (Adenine Nucleotide
Translocator) of the inner membrane and cyclophilin−D.
<b>Cyclophilin−D</b> protein binds to ANT to promote MPTP
formation [<A HREF="http://www.biochemj.org/bj/383/0101/bj3830101.htm"
TARGET="_blank">BIOCHEMICAL JOURNAL; Li,Y; 383(Pt 1):101-109 (2004)</A>], possibly
by increasing the sensitivity of the MPTP components to the effects of
Ca<sup>2+</sup> [<A HREF="http://circres.ahajournals.org/cgi/content/full/93/4/292"
TARGET="_blank">CIRCULATION RESEARCH; Weiss,JN; 93(4):292-301 (2003)</A>].
The entry of large solutes and accompanying water into the
matrix causes the mitochondrion to swell and burst, releasing cytochrome−c
into the cytoplasm.
<p>The <b>Ca<sup>2+</sup>−independent case</b> requires two
separate events for cytochrome−c release: (1) formation of large
pores in the outer mitochondrial membrane by <b>Bax/Bak</b> proteins and (2) release
of cytochrome−c from the inner mitochondrial
membrane [<A HREF="http://www.pnas.org/cgi/content/full/99/3/1259"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Ott,M; 99(3):1259-1263 (2002)</A>]. The Ca<sup>2+</sup>−independent case
can lead to
<a href="http://en.wikipedia.org/wiki/Apoptosis" target="_blank">apoptosis</a>,
whereas the Ca<sup>2+</sup>−dependent case is invariably associated with
<a href="http://en.wikipedia.org/wiki/Necrosis" target="_blank">necrosis</a>.
In apoptosis the MPTP opens only briefly (if it opens at all), whereas in necrosis
the MPTP remains open. Apoptosis requires ATP energy, but ATP energy is depleted
if the MPTP remains open [NATURE; Halestrap,A; 434:578-579 (2005)]. The threshold
amount of Ca<sup>2+</sup> which causes MPTP opening in lymphocytes, brain and liver
of old mice is significantly lower than that of young mice [BIOCHEMICAL AND
BIOPHYSICAL RESEARCH COMMUNICATIONS; Mather,M; 273(2):603-608 (2000)].
<A HREF="../nutrceut/CoEnzymeQ.html" TARGET="_blank">CoEnzyme Q<SUB>10</SUB></a>
has been shown to reduce apoptosis
by direct inhibition of the MPTP</a> [<A HREF="http://www.jbc.org/cgi/content/full/278/30/28220"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Papucci,L; 278(30):28220-28228 (2003)</A>].
<br clear=all>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Cardiolipin</B></CAPTION>
<TR><TD WIDTH="400">
<img src="Cardiolipin.jpg" width="400" height="150"
alt="Cardiolipin">
</TR></TD>
</TABLE>
<p>Cytochrome−c is normally held to the inner mitochondrial membrane by the
lipid <b>cardiolipin</b> (diphosphatidylglycerol). Cardiolipin composes 10% of
the inner mitochondrial membrane and is present at lower concentrations in the
outer mitochondrial membrane (especially near contact sites between the
two membranes). This distinctive lipid is found only in mitochondrial
membranes. Mitochondrial membrane cardiolipin content declines with age, resulting
in a decline in cytochrome−c activity. 40% lower cardiolipin content and
35% lower cytochrome−c activity has been demonstrated in old rats
compared to young rats. Restoration of membrane cardiolipin content restored
cytochrome−c activity [FEBS LETTERS; Paradies,G; 406(1-2):136-138
(1997)].
<p>Oxidation of cardiolipin releases cytochrome−c from the
inner mitochondrial membrane, but cytochrome−c will not be released into
the cytoplasm to induce apoptosis without the formation of large pores in the
outer mitochondrial membrane by <b>Bax/Bak</b> protein. <b>Bax/Bak</b> membrane
permeabilization occurs preferentially at cardiolipin-rich contact sites between
the outer and inner mitochondrial
membrane [<A HREF="http://www.biomedcentral.com/content/pdf/1471-2121-2-22.pdf"
TARGET="_blank">BMC CELL BIOLOGY; Lutter,M; 2:22-30 (2001)</A>]. But <b>Bax/Bak</b>
permeabilization of the outer membrane alone may be sufficient to induce apoptosis.
<p>If only one or a few mitochondria
release cytochrome−c apoptosis may not occur, but the damaged mitochondria
would themselves be degraded. By this means a few aberrant mitochondria which
are producing excessive free radicals can be eliminated.
<p>(For more about mechanisms of <b>apoptosis</b> see
<a href="#senescence" target="_blank">Cellular Senescence and Apoptosis in Aging</a>)
<BR CLEAR=all>
<P><a href="#contents"> (return to contents)</a>
<H3><a name="glycation">IX. THE GLYCATION THEORY OF AGING </a></H3>
<P><B>Proteins</B> are long chains of amino acids
(amino acid polymers, or polypeptides). 20 different amino acids occur in
animal proteins. Amino acids are all organic compounds
with a protonated <B>amino</B>
group [−NH<SUB>3</SUB><B><SUP>+</SUP></B>] and an ionized <B>carboxyl</B>
group [−COO<B><SUP>−</SUP></B>] attached to the same
(alpha-position) carbon atom.
<center><img src="amino.gif" width="414" height="159" alt="[AMINO ACIDS]"></center>
<p>
<center><img src="peptide.gif" width="446" height="188" alt="[THE PEPTIDE BOND]"></center>
<BR CLEAR=all>
Linkage of the carboxyl group of one amino
acid with the amino group of another amino acid (and the loss of a water
molecule) is the basis of the <B>peptide bond</B>. Peptide bonds are
formed on cell ribosomes during protein synthesis.
<P> Proteins can be damaged both by free-radicals and by glycation.
<B>Glycation</B> (also called the <B>Maillard reaction</B>, or
<B>non-enzymatic glycosylation</B>) is a reaction by which <B>reducing sugars</B> become
attached to proteins without the assistance of an enzyme. (For details on the properties
of reducing sugars, see <a href="../cryonics/vitrify.html#sugars"
target="_blank">cryopreservation with sugars</a>.)
This attachment
occurs at the free amine group of lysine or arginine, which is not involved
in the peptide bond. The reaction between glucose and a lysine amino acid
in a protein molecule can be represented as follows:
<P><center><img src="amadori.gif" width="415" height="580" alt="[glycation/oxidation
reactions form AGEs ]"></center>
<BR CLEAR=ALL>
<P> In the diagram, glycation is the formation of a double-bond between the
glucose aldehyde-group and the lysine amino group with the elimination of
a water molecule. The double-bond between the glucose carbon and the lysine
nitrogen is an <B>imine</B> (also known as a <B>Schiff base</B>).
The imine can quickly re-arrange atoms such that the 2-carbon (2nd carbon)
of the glucose loses its two hydrogens — resulting in a <B>carbonyl
group</B> (>C=O) and in hydrogen-saturation of the carbon & nitrogen which
formerly constituted the imine. This re-arrangement structure is called an
<B>Amadori product</B> (a ketoamine). Both glycation and Amadori product
formation are completely reversible reactions. But the formation of
<B>Advanced Glycation End-products</B> (<B>AGEs</B>) by oxidation of
Amadori products is irreversible.
<P> AGEs in tissues increase the rate of free radical production to 50-times
the rate of free-radical production by unglycated proteins. Histochemical
analysis of the hippocampus of human cadavers shows that chronological age
can be estimated by hippocampal AGE
levels [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/11260301"
TARGET="_blank">HISTOPATHOLOGY; Sato,Y; 38(3):217-220 (2001)</A>].
AGEs attached to LDL-cholesterol accelerates
oxidation and subsequent atherosclerosis. The irreversible cross-linked
proteins of AGEs in vessel collagen also contributes to atherosclerosis, as
well as to kidney failure — conditions worsened in diabetes
[DIABETES 46(Suppl 2):S19-S25 (1997)]. Cataracts are composed of urea-insoluble
proteins in the lens of the eye. AGEs aggravate protein cross-linking
in the plaques & tangles of
<A HREF="../lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's Disease</A>,
thereby accelerating neuron death [BRAIN RESEARCH REVIEW 23:134-143 (1997)].
AGEs can be formed in the body from glycation & oxidation or can be
ingested directly from browned foods (such as fried poultry skin) or tobacco smoke.
Approximately one third of absorbed dietary AGEs are excreted in urine and rest is
presumably incorporated into body
tissues [<A HREF="http://www.pnas.org/cgi/content/full/94/12/6474"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Koschinsky,T;
94(12):6474-6479 (1997)</A>]. (For more on the effect of ingested AGEs, see
<a href="../health/MacroNut.html#AGEs" target="_blank">INGESTION OF ADVANCED GLYCATION
END-PRODUCTS (AGES)</a>.)
<P> The higher glycation rate in diabetics is undoubtedly related to
the fact that diabetes greatly resembles accelerated aging. Hemoglobin glycation is
often used as a time-integrated (as opposed to instantaneous) measure of blood
glucose levels in diabetics. AGEs
are universal symptoms of aging — adversely affecting skin, lungs, muscles, blood
vessels and organ-function in general. Increased insulin resistance and other
symptoms of diabetes are commonly seen features of aging. Diabetes-like
atherosclerosis and the resultant generalized reduction in blood flow
has an adverse effect on most organ systems.
<P> Although most proteins are short-lived (mouse liver proteins
have a half-life of 3 days) some proteins, such as crystallins in
the eye lens of mammals, can last a lifetime. Lens crystallines, collagen
and basement membrane are the proteins
most vulnerable to cross-linking and AGE formation because they are
the most long-lived proteins, with a slow rate of turnover.
<p>AGE cross-links
can be broken by N−PhenacylThiazolium Bromide (<B>PTB</B>), but
3−phenacyl-4,5-dimethylthiazolum chloride (<B>ALT−711</B>,
<b><a href="http://en.wikipedia.org/wiki/Alagebrium" target="_blank">alagebrium</a></b>)
has proven to be even more effective than PTB in breaking
cross-links [<A HREF="http://circres.ahajournals.org/cgi/content/full/92/7/785"
TARGET="_blank">CIRCULATION RESEARCH; Candido,R; 92(7):785-792 (2003)</A>]. Alagebrium
has proven effective in reducing systolic blood
pressure [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/15607432"
TARGET="_blank">AMERICAN JOURNAL OF HYPERTENSION; Bakris,GL; 17(12 Pt 2):23S-30S
(2004)</A>] and providing therapeutic benefit for patients with diastolic heart
failure [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/15812746"
TARGET="_blank">JOURNAL OF CARDIAC FAILURE; Little,WC; 11(3):191-195 (2005)</A>].
<A HREF="../nutrceut/carnosine.html"
TARGET="_blank">Carnosine</A> also has anti-glycating
effects [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/16181134"
TARGET="_blank">CURRENT MEDICINAL CHEMISTRY;Guiotto,A; 12(20):2293-2315
(2005)</A>].
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B></B></CAPTION>
<TR><TD WIDTH="500">
<img src="Glucosepane.jpg" width="500" height="200" alt="Major cross-link in collagen">
</TR></TD>
</TABLE>
<P>In the extracellular matrix of senescent skin, the major protein cross-link
is the arginine-lysine glucose product
<B>glucosepane</B> [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/19415980"
TARGET="_blank">REJUVENATION RESEARCH; Svantesson,J; 12(3):137-148 (2009)</A>].
In non-diabetic 90-year-olds
glucosepane accounts for about 50 times the cross-linking as all other forms of
cross-linking, and is more than twice as prevalent in diabetics as in
non-diabetics [<A HREF="http://www.jbc.org/cgi/content/full/280/13/12310"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Sell,DR; 280(13):12310-12315
(2005)</A>]. In diabetics, prosclerotic growth factors like <B>TGF−ß</B>
(Transforming Growth Factor beta) promote extracellular matrix synthesis.
<P>Collagen accounts for about a third of total body protein in mammals. Collagen
cross-linking in skin, muscle and organs throughout the body leads to the sinewy,
inelastic tissue characteristic of aging. Cross-linking of proteins makes connective
tissue lose elasticity, increases arteriosclerosis, reduces kidney function, slows
wound healing, reduces the vital capacity of the lung and contributes to cataracts.
Cross-linking also contributes to arteriosclerosis by making LDL-cholesterol
unrecognizable to LDL-receptors, thereby increasing LDL in the blood.
<P> Birds have blood glucose levels that are 2−10 times higher, metabolic rates
that are more than double and body temperatures 2ºC−4ºC higher — than
similarly-sized mammals. Higher
temperatures & higher blood glucose would be expected to accelerate
glycation & AGE formation in birds — yet their lifespans are
considerably longer than those of comparably-sized mammals. Hummingbirds have the
highest levels of glycated hemoglobin of any bird, but these levels are lower
than those seen in non-diabetic humans, partially because of higher red blood
cell turnover and partially because of better membrane control of glucose
transport [COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY; Beuchat,CA; 120(Part A):
409-416 (1998)].
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Muscle carnosine correlates with mammalian lifespan</B></CAPTION>
<TR><TD WIDTH="450">
<img src="Carnosine.gif" width="450" height="300"
alt="Muscle carnosine correlates with mammalian lifespan">
</TR></TD>
</TABLE>
<P>Birds have twice the
blood concentration of antioxidant uric acid as humans and a much lower rate of
free radical production. A study of hens showed less than one hundredth the
quantity of <a href="../health/MacroNut.html#AGEs"
target="_blank">Advanced Glycation End-products (AGES)</a> as would be found in
humans [JOURNALS OF GERONTOLOGY; Iqbal,M; 54A(4):B171-B176 (1999)]. The
dipeptide <a href="../nutrceut/carnosine.html"
target="_blank">carnosine</a> (ß−alanyl-L-histidine) both inhibits glycation
and has antioxidant metal chelating activity. Skeletal muscle concentrations
of carnosine correlate with lifespan in mammals [BRAIN RESEARCH REVIEWS
23:134-143 (1997)]. Vitamin C also has anti-glycation properties as well
as antioxidant action [DIABETES; Davie,SJ; 41(2):167-173 (1992)].
<P> Glucose is not the most active sugar for glycation. Galactose is
5 times more reactive than glucose, fructose is 8 times more reactive,
deoxyglucose is 25 times more reactive, ribose is 100 times more reactive
and deoxyribose is 200 times more reactive. [<B>Sucrose</B> is composed of the
two monosaccharides glucose & fructose, whereas <B>lactose</B> (milk-sugar)
is composed of the two monosaccharides glucose & galactose.] Mice injected
with galactose are models of accelerated
aging [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/10405984"
TARGET="_blank">MECHANISMS OF AGING AND DEVELOPMENT; Song,X; 108(3):239-251
(1999)</A>]. Some aldehydes
produced by lipid peroxidation are more reactive than any of the sugars. Glucose
assumes the cyclic conformation more readily than any other monosaccharide, making
it the most resistant to both glycation and oxidation of any sugar. It is
no evolutionary accident that the least reactive of sugars is the sugar organisms
most use for energy.
<p>Lipids as well as proteins are subject to glycation. Lipid glycation of
LDL cholesterol increases the LDL oxidation associated with
atherosclerosis [<A HREF="http://atvb.ahajournals.org/cgi/content/full/20/2/467"
TARGET="_blank">ATHEROSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY; Ravandi,A;
20(2):467-477 (2007)</A>]. <a href="../nutrceut/MiscSupp.html#B6"
target="_blank">Vitamin B<sub>6</sub></a> prevents lipid glycation more effectively than other
common anti-glycation agents [<A HREF="http://www.jlr.org/cgi/content/full/47/5/964"
TARGET="_blank">JOURNAL OF LIPID RESEARCH; Higuchi,O; 47(5):964-974 (2006)</A>].
<P>(For more information on glycation, see the <A HREF="http://imars.case.edu/"
TARGET="_blank">International Maillard Reaction Society</A>.)
<P><a href="#contents"> (return to contents)</a>
<BR CLEAR=all>
<H3><a name="protein">X. PROTEIN DAMAGE AND MAINTENANCE IN AGING </a></H3>
<P> Not all of the damaging effects of sugar are due to glycation.
Glucose & fructose are reduced to <B>sorbitol</B> by the enzyme aldol
reductase. Sorbitol is a tissue toxin, contributing to retinopathy,
neuropathy, cataracts and kidney disease in diabetes. And not all protein
cross-linking is due to glycation. Aldehydes produced by lipid peroxidation,
such as <B>M</B>alon<B>D</B>i<B>A</B>ldehyde (<B>MDA</B>, propanedial),
can cross-link proteins by forming covalent bonds with lysine amino acids.
<P><TABLE BORDER = "2">
<TR align="left"><TD WIDTH="600">
<TR><TH>Cross-linking of protein with lipid peroxidation product MDA</TH></TR>
<TR><TD>
<img src="MalCross.gif" width="600" height="150"
alt="[ Cross-linking of protein with lipid peroxidation product MDA ]">
</TD></TR>
</TABLE>
<P>Mitochondria produce nitric acid at a rate comparable to the rate of superoxide
production [<A HREF="http://www.jbc.org/cgi/content/full/273/18/11038"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; 273(18):11038-11043 (1998)</A>].
Peroxynitrite formed by reaction of nitric oxide with superoxide can irreversibly
form covalent bonds with tyrosine amino acids in proteins, thereby blocking phosphorylation.
Phosphorylation & dephosphorylation of enzymes by kinases & phosphatases at tyrosine,
serine & threonine protein residues play a central role in enzyme activation/deactivation
& <A HREF="http://www.benbest.com/health/cancer.html#signalling"
TARGET="_blank">cell signalling</A> — both of which would be disrupted by
nitrotyrosine formation.
<P> Another form of protein damage is <B>racemization</B>, although this kind of
protein damage is less serious than glycation. Cells can only make proteins
from L−isomer ("left-handed") amino acids. Only L−isomer proteins
are functional. Some D−isomer ("right-handed") proteins are not
only non-functional, but harmful. Thermal energy causes a small percentage
of proteins to spontaneously change from the L−form to the D−form
— and this form of molecular deterioration is known as <B>racemization</B>.
(Racemization allows for determination of an animal's age from the ratio of
D−form to L−form in the dentine of a tooth).
<P>Asparagine and glutamine amino acids on proteins spontaneously deaminate, especially
when a glycine is in the adjacent carboxyl position. The rate of deamination of asparagine
is 400 times greater than for glutamine. When the enzyme which can repair this protein
damage is missing from experimental (knockout) mice, the mice suffer brain damage and
die young [<A HREF="http://www.jbc.org/cgi/content/full/276/23/20695"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; 276(23):20695-20702 (2001)</A>].
<P> <B>Carbonyl</B> (<B>>C=O</B>, ie, aldehyde or ketone) content of protein is used as
a rough measure of protein oxidation. Carbonyl formation is irreversible, so oxidized
proteins must be removed by degradation. Carbonyl content of protein in an
animal cell increases exponentially with age. At least 30−50% of protein
is oxidized in old animals, which correlates well with an estimated
30−50% decrease in enzyme activity in old animals. A study on houseflies showed an
association between protein carbonyls and life expectancy, possibly indicative of
an effect on rate of
aging [<A HREF="http://www.pnas.org/cgi/content/abstract/90/15/7255"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Sohal,RS;
90(15):7255-7259 (1993)</A>].
<P>A study of several species of mammals & a bird (pigeon) indicated a linear
relationship between oxidative damage to protein and maximum life span [EXPERIMENTAL
GERONTOLOGY 31(3):365-372 (1996)]. Cysteine & methionine are by far more vulnerable
to oxidation by reactive oxygen species than any other protein amino acids because of
their sulfhydryl groups. Oxidation of cysteine sulfhydryls can result in disulfides that
cause protein aggregation and lipofuscin.
<a href="http://en.wikipedia.org/wiki/Naked_mole_rat" target="_blank">Naked mole rats</a>
(which live at least 9 times longer than mice) have much more oxidative damage to
proteins than mice, but maintain that level of damage unchanged for two decades. Although
mice have a 12% oxidative decline in cysteine with age, naked mole rats
show no age-related change in cysteine for two
decades [<A HREF="http://www.pnas.org/content/106/9/3059.long"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Perez,VI; 106(9):3059-3064 (2009)</A>].
<p> <a href="http://en.wikipedia.org/wiki/Methionine_oxidation"
target="_blank">Methionine is oxidized</a> to methionine sulfoxide, but
methionine sulfoxide reductases enzymatically regenerate
methionine [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062201/"
TARGET="_blank">BIOPHYSICA ET BIOCHEMICA ACTA; Lee,BC; 1790 (11):
1471-1477 (2009)</A>]. Additionally, isomerases can reverse the aberrant disulfide
bridges — the only known enzymatic repairs of protein oxidation [FREE RADICAL BIOLOGY
& MEDICINE; Shringarpure,R; 32(11):1084-1089 (2002)]. Transgenic fruit flies that
overexpress methionine sulfide reductase primarily in the nervous system have shown
a median lifespan extension of about
70% [<A HREF="http://www.pnas.org/cgi/content/full/99/5/2748"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); 99(5):
2748-2753 (2002)</A>]. In one study, methionine sulfoxide reductase
knockout-mice showed reduced lifespan and increased carbonyl content on
protein [<A HREF="http://www.pnas.org/cgi/content/full/98/23/12920"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); 98(23):
12920-12925 (2001)</A>], but another study showed no reduction in
lifespan [<A HREF="http://www.fasebj.org/cgi/content/full/23/10/3601"
TARGET="_blank">THE FASEB JOURNAL; Salmon,AB; 23(20):4601-3608 (2009)</A>].
Reducing dietary methionine to a fifth the normal intake has increased
the lifespan of rats by 30% [JOURNAL OF NUTRITION; Orentreich,N; 123(2):269-274 (1993)].
Body weight is just over half normal for the rats and there are increased blood as well
as decreased tissue levels of
glutathione [<A HREF="http://www.fasebj.org/cgi/content/full/8/15/1302"
TARGET="_blank">THE FASEB JOURNAL; Richie,JP; 8(15):1302-1307 (1994)</A>].
<P> Oxidized protein is more vulnerable to cross-linking by lipid
peroxidation aldehydes such as MDA & 4−HNE [FEBS LETTERS 405:21-25 (1997)].
Hydroxyl radicals cause protein crosslinking by the formation of dityrosine bridges. Oxidized
& cross-linked proteins are resistant to degradation and therefore contribute to the
accumulation of damaged proteins in many degenerative diseases.
<P>Cellular proteins are continually being degraded (hydrolyzed) within cells by
proteolytic enzymes, both for regulation of cellular processes and for "quality control"
of proteins (eliminating malformed or malfunctional ones). Transcription factors and cell-cycle
proteins must be quickly eliminated after having served their purpose. The four major classes
of cellular proteolytic enzymes are (1) caspases (2) calpains (3) cathepsins
and (4) proteasomes.
<P><B>Caspases</B> are mainly active in apoptosis and are therefore in the category of regulatory
proteases. <B>Calpains</B> are Ca<SUP>2+</SUP>−dependent, ATP-independent proteases that mainly
degrade membrane & cytoskeletal proteins (as well as certain transcription factors). <B>Cathepsins</B>
are the major class of proteolytic enzymes found in lysosomes, although there are others. (As well, lysosomes
contain enzymes for degrading lipids, carbohydrates and nucleic acids.)
<A HREF="http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/P/Proteasome.html"
TARGET="_blank">Proteasomes</A> are enzymatic, proteolytic "machines".
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Proteasome structure and activity</B></CAPTION>
<TR><TD WIDTH="500">
<img src="proteasomes.jpg" width="500" height="300" alt="Proteasome structure and activity">
</TR></TD>
</TABLE>
<P>Normally, most damaged or misfolded protein — as well as obsolete regulatory protein — is
eliminated by the barrel-shaped proteasomes, which are found both in the nucleus and in the
cytoplasm. The core "barrel", called the <B>20S proteasome</B>, is capped on one or
both ends by <B>19S regulatory units</B>, and the whole structure is called the <B>26S proteasome</B>.
Proteins are hydrolyzed inside the 20S proteasome core. The 19S regulatory units assist in
recognition and delivery to the 20S core of proteins that have been marked for degradation by
chains of <B>ubiquitin</B> (a 76-amino acid globular protein). <B>Ubiquitin-activating enzymes</B> use ATP
to add ubiquitin to proteins requiring degradation. When the chains reach a threshold length of four
ubiquitin subunits, the marked protein is hydrolyzed by the proteasome into reusable peptides and ubiquitin
molecules. Oxidized proteins tend to be partially unfolded (denatured) and more hydrophobic, which may make
them directly recognizable to the 20S cores, such that energy-consuming ubiquitination is not
required for degradation.
<P>Proteasome activity declines with age. Polyubiquinated chains of defective proteins bind to
the 19S regulatory units blocking the passageway and preventing recognition of other
ubiquinated proteins. Even when the 19S regulatory units are clear, accumulating large
masses of cross-linked proteins cannot enter the proteasome, which has a 5−6 nanometer size opening.
<P>Degradation of cellular organelles, proteins and other materials by lysosomes is called
<B>autophagy</B>, subdivided into macroautophagy, microautophagy, and CMA. In
<B>macroautophagy</B> there is a sequestration of complete portions of the
cytosol (often including phagocytosed material or organelles) into a double membrane vesicle
known as the <B>autophagosome</B>, which migrates to the lysosome and fuses with the lysosome
membrane. In <B>microautophagy</B> the lysosome membrane itself engulfs portions of the cytoplasm.
Mice with defective autophagy suffer
neurodegeneration [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/16625204"
TARGET="_blank">NATURE; Hara,T; 441:885 (2006)</A>] and DNA
damage [<A HREF="http://genesdev.cshlp.org/content/21/11/1367.long"
TARGET="_blank">GENES & DEVELOPMENT; Mathew,R; 21(11):1367-1381 (2007)</A>]. Macroautophagy is
mainly controlled by the kinase
<a href="http://en.wikipedia.org/wiki/Mammalian_target_of_rapamycin" target="_blank">mammalian
Target of Rapamycin</a> (<b>mTOR</b>), a downstream component of the
<a href="http://en.wikipedia.org/wiki/Phosphoinositide_3-kinase" target="_blank">PI3K pathway</a>,
which is inhibited by <a href="http://en.wikipedia.org/wiki/Sirolimus" target="_blank">rapamycin</a>
or absence of nutrition. Rapamycin extends both median and maximum lifespan when fed to
mice [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786175/"
TARGET="_blank">NATURE; Harrison,DE; 460:392-395 (2009)</A>]
<p>Proteins can also be brought into the lysosome for degradation by
<B>Chaperone-Mediated Autophagy</B> (<b>CMA</b>)
in which members of the hsp70 heat shock protein family (the chaperones) attach to a target
protein and then bind to a lysosome receptor protein. CMA operates on proteins having the exposed
<B>KFERQ</B> pentapeptide (K=Lysine, F=Phenylalanine, E=Glutamate, R=Arginine, D=Glutamine —
<A HREF="http://www.ncbi.nlm.nih.gov/Class/MLACourse/Modules/MolBioReview/iupac_aa_abbreviations.html"
TARGET="_blank">IUPAC amino acid
abbreviations</A>) [<A HREF="http://www.molbiolcell.org/cgi/content/full/15/11/4829"
TARGET="_blank">MOLECULAR BIOLOGY OF THE CELL; Kiffin,R; 15(11):4829-2840 (2004)</A>]. Upon
arrival at the lysosome membrane, the chaparone/protein complex binds to the membrane protein
<a href="http://en.wikipedia.org/wiki/LAMP2" target="_blank">LAMP−2a</a>. The decline in
CMA activity in aging is due to declining LAMP−2a in the lysosome
membrane [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722716/"
TARGET="_blank">NATURE MEDICINE; Zhang,C; 14(9):959-965 (2008)</A>].
<P>Proteins with short half-lives tend to be broken-down by the proteasome, whereas proteins with
half-lives in excess of ten hours tend to be degraded by autophagy. Blockage of proteasomes by
protein aggregates would result in cell dysfunction due to the inability to degrade short-lived
regulatory proteins. Impaired degradation of p53 protein can result in excessive cell senescence or
apoptosis. Impaired proteasome degradation of immune system regulators like I<I>κ</I>B can
result in immune deficiency. Protein aggregation can also impair chaperone-mediated autophagy, as in the
case of the aggreations of the presynaptic protein α-synuclein into the Lewy bodies of
Parkinson's Disease [SCIENCE; Cuervo,AM; 305:1292-1295 (2004)].
<P>With aging, lysosomes of postmitotic cells increasingly become bloated
with aggregates of oxidized, glycated, cross-linked proteins which are resistant to enzymatic
degradation — material called <A HREF="../lifeext/aging.html#toxins" TARGET="_blank"><B>lipofuscin</B></A>.
(When lysosomes become bloated with similar material due to disease processes, it is called <B>ceroid</B>.)
<P>The "error catastrophe" theory of aging proposed that accumulating damage to synthesized
proteins resulted in damage to the machinery of synthesis itself, leading to an escalating viscious circle
of malfunctioning cellular components. But the rate of both protein synthesis and protein degradation
declines with age, and the inability to eliminate damaged macromolecules may be more catastropic than
the synthesis of new defective ones.
<P>Ubiquitin levels and protease activity are increased in conditions of stress.
Life extension associated with stress response may stimulate DNA repair or anti-oxidant enzyme production,
but it can also be a form of hibernation & reduced functionality insofar as
shielded proteins are less capable of performing their normal functions.
<P> The production of <a href="http://en.wikipedia.org/wiki/Heat_shock_protein"
target="_blank"><B>heat-shock proteins</B></a> (<B>HSPs</B> — cellular
protection from thermal and other stresses) can be increased
by a transient elevation of temperatures that could ordinarily kill a
cell. Increase longevity and robustness resulting from sublethal stress (<B>hormesis</B>)
has been demonstrated in fruit flies and nematodes. The magnitude
of induction of heat-shock proteins (particularly the Hsp70 family — which are
approximately 70 kilodaltons in size) is significantly
reduced with aging [EXPERIENTIA 50:1092-1098 (1994)]. The reported
incidence of heat stroke among those 65 years of age or older is ten
times that of younger persons.
<P> Although originally discovered in <B><I>Drosophila</I></B> (fruit flies) in response to
heat, HSPs are now known to also function against other cell stresses such as irradiation,
metal poisons and oxidation (even exercise). HSPs enhance cytokine signalling and antigen
presentation to lymphocytes [ANNALS OF THE NEW YORK ACADEMY OF SCIENCES; Moseley,PL;
856:206-213 (1998)]. Many cancer cells over-express HSPs, enhancing their survival. HSPs
are of remarkably similar structure in nearly all cells, including those from bacteria,
plants and mammals. Birds, however, have a unique heat shock transcription factor that
is induced in cell
proliferation [<A HREF="http://www.fasebj.org/cgi/content/full/15/7/1118"
TARGET="_blank">THE FASEB JOURNAL; Pirkkala,L; 15(7):1118-1131 (2001)</A>] — suggestive
of the possibility that HSP could be another factor underlying the exceptional longevity
of birds.
<p>Many HSPs are
constitutively expressed (rather than expressed by induction), such as the members of
the ATP-driven Hsp70 family that reside by ribosomes to assist in folding of newly formed
proteins. Some HSPs are true "molecular chaperones" that assist other proteins
in transit across intracellular membranes. Some HSPs may protect telomere proteins
or telomerase. Some HSPs evidently act by binding to incompletely folded metabolic
proteins, protecting them in an inactive state until the traumatic stress
has passed. Elderly transgenic mice that overexpress Hsp70 show a recovery
of muscles from exercise comparable to that seen in young
mice [<A HREF="http://www.fasebj.org/cgi/content/full/18/2/355"
TARGET="_blank">THE FASEB JOURNAL; Pirkkala,L; 18(2):355-367 (2004)</A>]
<P>Increased expression of the small HSP proteins in the motoneurons of
<B><I>Drosophila</I></B> has increased lifespan by 15% when expressed in the
cytoplasm (Hsp23) and 30% when expressed in mitochondria (Hsp22). Despite
the fact that expression was limited to motoneurons, the flies showed an increase in
resistance to oxidative injuries by paraquat of up to
35% [<A HREF="http://www.fasebj.org/cgi/content/short/03-0860fjev1"
TARGET="_blank">THE FASEB JOURNAL; Morrow,G; 18(3):598-599 (2004)</A>]. The longevity
effect of small HSPs may be due to their ability to prevent toxic aggregations
of proteins.
Heat-shock protein response is reduced in aging cells and is elevated in the cells of
CRAN (<A HREF="../calories/calories.html" TARGET="_blank">Caloric Restriction with
Adequate Nutrition</A>) organisms. <a href="../nutrceut/phytochemicals.html#quercetin"
target="_blank">Quercetin</a> promotes
apoptosis in cancer cells (among other cells) by inhibiting the synthesis of heat
shock protein HSP70 [CANCER RESEARCH; Wei,Y; 54:4952-4957 (1994)]. If stress
resistance is primarily due to HSPs, it is noteworthy that stress resistance of
fibroblasts from 8 mammalian species correlates linearly with species lifespan
for a variety of stresses [FREE RADICAL BIOLOGY & MEDICINE; Kapahi,P;
26(516):495-500 (1999)].
<P><a href="#contents"> (return to contents)</a>
<H3><a name="dna">XI. DNA DAMAGE AND DNA REPAIR </a></H3>
<P> Cell structure and metabolism operates under the direction of genes,
which are located in the <B>DNA</B> (<B>D</B>eoxyribo<B>N</B>ucleic <B>A</B>cid)
of the chromosomes of the animal cell nucleus. DNA coding is determined by
4 nucleic acid <B>bases</B>: <B>Adenine</B>, <B>Thymine</B>, <B>Cytosine</B>
and <B>Guanine</B>. Adenine and Guanine are known as <B>purines</B>, whereas
Thymine and Cytosine are <B>pyrimidines</B>. <B>RNA</B> (<B>R</B>ibo<B>N</B>ucleic
<B>A</B>cid) also contains 4 nucleic acid bases, but differs from DNA by
using the base <B>Uracil</B> in the place of Thymine (Uracil is also a
pyrimidine).
<P>The nucleic acid bases combine with either a ribose or
deoxyribose sugar molecule to form <B>nucleo<U>s</U>ides</B>: <B>Adenosine</B>,
<B>Cytidine</B>, <B>Guanosine</B> and <B>Uridine</B> in RNA — or
<B>Deoxyadenosine</B>, <B>Deoxycytidine</B>, <B>Deoxyguanosine</B>
and <B>Deoxythymidine</B> in DNA. Addition of phosphate groups to nucleosides
results in <B>nucleotide phosphates</B>, also called <B>nucleo<U>t</U>ides</B>.
The nucleotides in RNA are <B>Adenylate</B>, <B>Cytidylate</B>, <B>Guanylate</B>
and <B>Uridylate</B>. Adenosine TriPhosphate (<B>ATP</B>) and deoxyAdenosine
TriPhosphate (<B>dATP</B>) are nucleotides.
<BR CLEAR=all>
<P><TABLE BORDER = "2">
<TR><TH>PYRIMIDINES</TH><TH>PURINES</TH></TR>
<TR><TD align="left">
<img src="pyrimidines.gif" width="400" height="150" alt="[ PYRIMIDINES ]">
</TD>
<TD align="left">
<img src="purines.gif" width="400" height="150" alt="[ PURINES ]">
</TD>
</TR>
</TABLE>
<BR CLEAR=all>
Both purines and pyrimidines are heterocyclic (built from rings that include
both carbon and nitrogen), but pyrimidines consist of a single
ring, whereas purines have two fused rings. Chains of these nucleic
acid molecules are paired with complementary chains to form the
twisting double helix of DNA.
<P> DNA serves as the template (model for copying) for production of both DNA
& RNA. DNA replication (and some DNA repair) is catalyzed by the enzymes
known as <B>DNA polymerases</B>. The production of messenger RNA (mRNA) using
DNA as a template is known as <B>transcription</B>, and is catalyzed by
<B>RNA polymerase II</B> enzyme. Once produced, mRNA leaves the
nucleus for <B>translation</B> of the mRNA code into protein on the ribosomes.
<BR CLEAR=all>
<P>
<center><TABLE BORDER = "2">
<TR>
<TH>PURINE/PYRIMIDINE BASE-PAIRINGS</TH>
<TH>BASE-PAIRINGS IN DNA STRANDS<TH></TR>
<TR>
<TD align="center">
<img src="bases1.gif" width="241" height="325" alt="[PURINE/PYRIMIDINE BASE-PAIRINGS]" >
</TD>
<TD align="center">
<img src="bases2.gif" width="216" height="271" alt="[BASE-PAIRINGS IN DNA STRANDS]" >
</TD>
</TR>
</TABLE>
</center>
<BR CLEAR=all>
<P> In normal DNA, the bases Adenine and Thymine are always paired
(connected by 2 hydrogen bonds) and the bases Cytosine
and Guanine are always paired (connected by 3 hydrogen bonds). A specific
sequence of 3 bases in DNA will cause the selection of a single amino acid
for protein synthesis. For example, GCA (Guanine, Cytosine, Adenine) will
select the amino acid Alanine in the synthesis of structural proteins and
enzymes. A <B>gene</B> is a hereditary unit composed of a sequence of
DNA bases that will code for a sequence of amino acids that form a
peptide or protein.
<P>The DNA bases are connected to sugar molecules (deoxyribose) and
the sugar molecules are linked together by phosphate molecules. More
precisely, an ester bond (oxygen bond) connects the 5' carbon
of one deoxyribose and another ester bond connects the 3' carbon
to another deoxyribose, and both ester bonds are connected to a phosphate,
forming a 5',3'−phosphodiester bond. The phosphate-linked sugars connected
to the bases form a single strand of DNA, which pairs with an <B><I>antiparallel</I></B>
strand of 3',5'−phosphodiester bonds to form the DNA double-helix.
<P>
<center><TABLE BORDER = "2">
<TR><TH>Single Strand of DNA</TH></TR>
<TR>
<TD align="center">
<img src="DNAstrnd.gif" width="500" height="600" alt="[Single DNA strand]" >
</TD>
</TR>
</TABLE>
</center>
<P> Animal genetic material in
the cell nucleus exists as a complex known as <B>chromatin</B> — which
consists of DNA, five histone proteins and some non-histone proteins.
<B>Histone</B> protein is not coagulated by heat and is composed of a
high proportion of the basic amino acids lysine & arginine, which are
positively-charged at physiological pH. Because DNA is negatively-charged
(due to phosphate groups), the positively-charged histones readily bind
to DNA.
<P> Four of the histones (H2A, H2B, H3 and H4) compact DNA about six-fold
into bead-like <B>nucleosomes</B>. A fifth histone (H1) binds to the DNA
between nucleosomes, causing a second-order compacting of the "string"
— compacting the chromatin another six-fold. Non-histone proteins aid
an even higher level of looping & coiling. With age, compacting of
chromatin increases, probably due to increasing covalent linking
between DNA and the chromosomal proteins. Because compacting helps determine
which genes are expressed and which genes are not, the increased
compacting of aging probably means a decline in gene expression. A 50%
reduction in chromatin-associated RNA polymerase II activity has been
demonstrated in the brains of old rats [MUTATION RESEARCH 275:317-329
(1992)].
<BR CLEAR=all>
<P><center><TABLE BORDER = "2">
<TR>
<TH>BEAD-LIKE NUCLEOSOMES</TH>
<TH>H1-COMPACTED NUCLEOSOMES<TH></TR>
<TR>
<TD align="center">
<img src="beads.gif" width="420" height="171" alt="">
</TD>
<TD align="center">
<img src="solenoid.gif" width="275" height="252" alt="">
</TD>
</TR>
</TABLE></center>
<BR CLEAR=all>
<P> Of the approximately 30,000 genes in the human
genome, it is estimated that only 2% of these are different from those of
a chimpanzee, which has half the estimated maximum lifespan of a human. The
longevity difference could be due to as few as a hundred genes or less. Also
of note is the fact that identical twins tend to die within 3 years of each
other, whereas fraternal twins tend to die within 6 years. Aging theories
associated with DNA include programmed aging (or programmed aging-resistance)
and theories that link aging with DNA damage/mutation or DNA repair
capability.
<P> "Wear&tear" of DNA can take two forms: mutation and DNA
damage. An analogy
illustrates the difference: the word ST<B>O</B>P can be <B>mutated</B> to
the word ST<B>E</B>P by the substitution of another letter, whereas if the
letter "O" is lost or altered, <B>damage</B> occurs, resulting in
the non-word ST<B>#</B>P. Substitution of a Thymine for an Adenine
would be a <B>mutation</B>, whereas loss of an Adenine
or methylation of a Guanine would be <B>damage</B>. The phenomena are not
independent, however, because methylated Guanine is known to be mutagenic.
Of chemicals known to be mutagenic in bacteria 85% are
carcinogenic (cancer-causing) in animals &mdas the basis of the
<A HREF="http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/AmesTest.html"
TARGET="_blank">Ames Test</A> for carcinogenicity.
<P> DNA damage tends to interfere with gene expression by preventing
transcription of RNA from DNA, whereas mutation usually results in
transcription that usually produces proteins with diminished or
altered functionality. Mutations that are not lethal to a cell are more
likely to be perpetuated in dividing cells. DNA damage rather than DNA
mutation is posited as a cause of aging.
<P> There are more than 200,000 DNA damage events per mammalian cell per
day due to oxidation, hydrolysis, alkylation, radiation or toxic chemicals.
Removal of purine or
pyrimidine bases from DNA (<B>depurination </B>and <B>depyrimidation </B>)
is often caused by hydrolysis or thermal disruption. The location on DNA where a
depurination or depyrimidation has occurred is called an <B>AP site</B>
(<B>AP</B>urinic or <B>AP</B>yrimidinic site). If AP sites are unrepaired
they decay to single-strand breaks. <B>Pyrimidine dimers</B> (usually cross-linking
of two adjacent thymine bases) frequently are produced by ultraviolet light.
<P> Types and frequency of DNA damage can be roughly illustrated
by the following table and representative pictures:
<P>
<img src="break.gif" width="223" height="368" alt="[DEPICTIONS OF DNA DAMAGE]" ALIGN="left">
<TABLE BORDER=7 CELLSPACING=3 CELLPADDING=3>
<CAPTION><H3><B>Types and Frequency of DNA Damage</B></H3>
<TR BGCOLOR="#FFFFFF"><TH><H4><B>TYPE OF DAMAGE</B></H4></TH><TH><H4><B>events/cell/day</B></H4></TH><TH><H4><B>% of total daily damage</B></H4></TH></TR>
<TR BGCOLOR="#FFFFFF"><TD><B>Single-strand break </B></TD><TD><B> 120,000</B></TD><TD><B>50.9</B></TD></TR>
<TR BGCOLOR="#FFFFFF"><TD><B>N<SUP>7</SUP>-MethylGuanine</B></TD><TD><B>84,000</B></TD><TD><B>35.6</B></TD></TR>
<TR BGCOLOR="#FFFFFF"><TD><B>Depurination </B></TD><TD><B> 24,000</B></TD><TD><B>10.2</B></TD></TR>
<TR BGCOLOR="#FFFFFF"><TD><B>O<SUP>6</SUP>-MethylGuanine</B></TD><TD><B> 3,120</B></TD><TD><B> 1.3</B></TD></TR>
<TR BGCOLOR="#FFFFFF"><TD><B>Oxidized DNA </B></TD><TD><B> 2,880</B></TD><TD><B> 1.2</B></TD></TR>
<TR BGCOLOR="#FFFFFF"><TD><B>Depyrimidation </B></TD><TD><B> 1,320</B></TD><TD><B> 0.5</B></TD></TR>
<TR BGCOLOR="#FFFFFF"><TD><B>Cytosine deamination </B></TD><TD><B> 360</B></TD><TD><B> 0.2</B></TD></TR>
<TR BGCOLOR="#FFFFFF"><TD><B>Double-strand breaks </B></TD><TD><B> 9</B></TD><TD><B> 0.01</B></TD></TR>
<TR BGCOLOR="#FFFFFF"><TD><B>Interstrand cross-links</B></TD><TD><B> 8</B></TD><TD><B> 0.01</B></TD></TR>
</TABLE>
<P>
<center><TABLE BORDER = "2">
<TR><TH>Illustrated Summary of Types of DNA Damage</TH></TR>
<TR>
<TD align="center">
<img src="DNAdamage.gif" width="500" height="600" alt="[DNA Damage Illustration]" >
</TD>
</TR>
</TABLE>
</center>
<BR CLEAR=all>
<P><TABLE BORDER = "2">
<CAPTION ALIGN=TOP><B>OXIDATIVE DAMAGE TO A NUCLEOSIDE: formation of 8−OHdG/8−oxoG</B></CAPTION>
<TR align="center"><TD WIDTH="650">
<TR><TH>8−OHdG from Guanosine with Hydroxyl</TH><TH>8−oxoG</TH></TR>
<TR><TD align="left">
<img src="OH_dG.gif" width="450" height="150" alt="[ 8−HydroxdeoxyGuanosine ]">
</TD>
<TD align="left">
<img src="oxoG.gif" width="250" height="200" alt="[8−oxo−7,6−dihydroGuanine ]">
</TD>
</TR>
</TABLE>
<BR CLEAR=all>
<P>More than 20 types of oxidative damage to nucleosides have been
documented [<A HREF="http://www.fasebj.org/cgi/content/full/17/10/1195"
TARGET="_blank">THE FASEB JOURNAL; Cooke,MS; 17(10):1195-1214 (2003)</A>].
The most frequent oxidative damage to DNA is believed to be the 8−hydroxylation/oxidation
of the guanine base to 8−hydroxydeoxyguanosine (<B>8−OHdG</B>), a molecule which is
equivalent to 8−oxo−7,8−dihydroguanine (<B>8−oxoG</B>) because
the hydroxyl hydrogen can easily move to the 7−position leaving a double-bonded oxygen
at the 8−position (a resonance form of the two structures). Singlet
oxygen reacts with DNA to produce
8−OHdG/8−oxoG [<A HREF="http://www.jbc.org/cgi/content/full/275/51/40601"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Ravanat,J; 275(51):40601-50604 (2000)</A>].
8−OHdG/8−oxoG is the most commonly studied biomarker of DNA oxidation [MUTATION
RESEARCH 424:51-58 (1999)] and is believed to constitute 5% of all oxidative DNA
damage [MUTATION RESEARCH; Dizdaroglu;M; 275(2-6):331-342 (1992)].
8−OHdG is mutagenic because it inhibits methylation and because it can be paired with
adenosine rather than cytosine during DNA replication leading to GC-to-AT conversion
(the most frequent kind of spontaneous mutation). Levels of 8−OHdG are inversely
related to lifespan in mammals [FREE RADICAL BIOLOGY & MEDICINE; Foksinski,M;
37(9):1449-1454 (2004)], and increase with age — but less so in animals
subjected to <A HREF="../calories/calories.html" TARGET="_blank">
Caloric Restriction with Adequate Nutrition</A> (CRAN) [FREE RADICAL BIOLOGY &
MEDICINE 32(9):882-889 (2002)]. Mitochondrial DNA rather than nuclear DNA is the primary
site of damage [<A HREF="http://www.fasebj.org/cgi/content/full/14/2/312"
TARGET="_blank">THE FASEB JOURNAL; Barja,G; 14(2):312-318 (2000)</A>].
In Western countries, females live about 10% longer than
males, and males have 4 times as much oxidative DNA damage
as females, presumably because females have more MnSOD and glutathione
peroxidase [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/12614843"
TARGET="_blank">FREE RADICAL BIOLOGY & MEDICINE;
Borras,C; 34(5):546-552 (2003)</A>]. Levels of
8−OHdG are 18 times higher than normal in intact DNA from the cerebrospinal fluid
of <A HREF="http://www.benbest.com/lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's
Disease</A> patients [ARCHIVES OF NEUROLOGY 58:392-396 (2001)]. Nuclear DNA in the
brain tissue of old mice accumulates 8−OHdG/8−oxoG at nearly four times the rate of young
mice [<A HREF="http://www.pnas.org/cgi/content/full/98/18/10469"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Hamilton,ML;
98(18):10469-10474 (2001)</A>]. Repair of 8−OHdG/8−oxoG has been shown to decline
significantly with age in
humans [<A HREF="http://www.jstage.jst.go.jp/article/jrr/44/1/44_31/_article/-char/en"
TARGET="_blank">JOURNAL OF RADIATION RESEARCH; Chen,S; 44(1):31-35 (2003)</A>]. Cigarette
smoking, age, and unhealthy diet correlate directly with not only urinary 8−OHdG/8−oxoG,
but urinary
N<SUP>7</SUP>-MethylGuanine [<A HREF="http://www3.interscience.wiley.com/cgi-bin/fulltext/121676017/HTMLSTART"
TARGET="_blank">CANCER SCIENCE; Tamae,K; 100(4):715-721 (2009)</A>].
<P>The most active DNA repair enzymes, <B>excision repair</B> enzymes, all operate on the
basis of damage or mutilation occurring to only one of the two strands of the DNA
double-helix such that the undamaged strand can be used as a template to repair the
damaged strand. The damaged area of the injured strand is cut-away (<B>excised</B>) by a
nuclease (or glycosylase) enzyme, and a new strand (or a single nucleotide) is constructed.
Even the simplest repair usually involves a team of enzymes.
<P><B>Glycosylase</B> (glycosidase) enzymes remove individually damaged nucleic acid bases (purines or
pyrimidines) from the deoxyribose sugars to which they are attached. Glycosylases remove
bases that have been oxidized or alkylated and also remove uracil from nDNA. The <B>MYH</B>
glycosylase removes adenine that has been incorrectly incorporated opposite 8−OHdG/8−oxoG.
<B>Endonuclease</B>
enzymes cleave the phosphodiester bonds to remove the sugar residues (which may or may
not still be connected to a base). There are at least fifteen <B>DNA polymerase</B>
enzymes which function in DNA repair to replace excised strands of DNA. <B>DNA ligase</B>
enzymes seal the strand by reforming the phosphodiester bonds. If a long section of
strand needs to be replaced, <B>helicase</B> enzymes may be required to unwind the DNA
before the injured section is excised — and rewind afterwards. Very long sections may
even require <B>topoisomerase</B> enzymes to unwind and rewind supercoils. Additional
enzymes are often required to recognize damage and recruit other enzymes into repair.
<P>There are three general categories of excision−repair enzymes:
(1) <B>Base Excision Repair</B> (<B>BER</B>, which repair/replace a single damaged
nucleic acid base) (2) <B>Nucleotide Excision Repair</B> (<B>NER</B>, for repairing
DNA strand damage ranging from 2−30 bases in length) and (3) <B>MisMatch Repair</B>
(<B>MMR</B>, for repairing mispaired nucleic acid bases).
<BR CLEAR=all>
<P><TABLE BORDER = "2" ALIGN=LEFT>
<CAPTION ALIGN=TOP><B>Base Excision Repair</B></CAPTION>
<TR><TD WIDTH="700">
<img src="BERpaths.jpg" width="600" height="700" alt="Base Excision Repair">
</TR></TD>
</TABLE>
<BR CLEAR=all>
<p>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Deamination of Cytosine</B></CAPTION>
<TR><TD WIDTH="200">
<img src="deamination.jpg" width="200" height="400" alt="Deamination of Cytosine">
</TR></TD>
</TABLE>
<P><B>Base Excision Repair</B> (<B>BER</B>) primarily repairs damage due to hydrolysis,
alkylation (usually methylation) or oxidation of single nucleic acid bases. Alteration of a
single base may not impede transcription and can often lead
to miscoding and thus to mutation. BER begins with recognition and removal of a damaged
nucleic acid base by one of many possible glycosylase enzymes, each of which specializes
in recognition of a particular type of base
damage [<A HREF="http://www.biochemj.org/bj/325/0001/bj3250001.htm"
TARGET="_blank">BIOCHEMICAL JOURNAL; Krokan,HE; 325(Pt 1):1-16 (1997)</A>].
BER has two subpathways, known as <B>short-patch BER</B>
and <B>long-patch BER</B>. Roughly 80−90% of BER is by the short-patch pathway,
which requires only 3 enzymes: a glycolsylase, an endonuclease and a polymerase.
Bifunctional glycosylases not only cleave the bond between the damaged base and the
sugar, but cleave the backbone with AP lyase activity. But
for obstinate base modification that cannot be fixed by the short-patch pathway, the
long-patch pathway strips-away 2−10 nucleotides, including the damaged base. A
larger number of proteins participate in the long-patch pathway, such as PCNA, RFC,
FEN1 and probably WRN. PCNA, RFC and a polymerase create a "flap" of
nucleotides that are removed by FEN1 (Flap ENdonuclease−1);
<P> Deamination of cytosine by hydrolysis is an example of DNA damage
repaired by short-patch BER. With the removal
of the (−NH<SUB>2</SUB>) group, cytosine becomes uracil, which is recognized by DNA
repair enzymes as being an abnormal base in DNA. (The fact that cytosine deaminates
so easily to uracil probably explains why thymine rather than uracil is normally
present in DNA — it is easier to detect a base not normally present). The repair
enzyme <B>uracil-DNA glycosylase</B> removes the uracil and then an <B>AP endonuclease</B>
cleaves the phosphodiester bonds, just as it would in the repair of any depurination or
depyrimidation. <B>DNA polymerase ß</B> is a specialized DNA polymerase that
is used for attaching the new base in BER, not for DNA replication. BER repair capabilities
dependent upon DNA polymerase ß have been shown to decline with age in mice, which
may underly increased vulnerability to cancer or even aging itself [MUTATION RESEARCH
500:135-145 (2002)]. Normal BER forms transient single-strand breaks, so it is
understandable that BER enzymes play an important role in single-strand break repair.
There are no known diseases associated with inherited defects of short-patch BER enzymes.
Individual glycosylase defects are not harmful because there are so many glycosylases which
can perform the same functions, whereas defects in the other short-patch BER enzymes are
fatal to embryos.
<P>One might imagine that increased expression of BER enzymes would improve DNA integrity,
but the opposite is true. Increased glycosylase expression increases DNA strand
breaks [<A HREF="http://mct.aacrjournals.org/cgi/content/full/3/8/955"
TARGET="_blank">MOLECULAR CANCER THERAPIES; Rinne,M; 3(8):955-967 (2004)</A>] as
does increased DNA polymerase ß
expression [<A HREF="http://nar.oxfordjournals.org/cgi/content/full/32/17/5104"
TARGET="_blank">NUCLEIC ACIDS RESEARCH; Canitrot,Y; 32(17):5104-5112 (2004)</A>].
Increased AP nuclease expression can increase genetic
instability [<A HREF="http://nar.oxfordjournals.org/cgi/content/full/33/1/298"
TARGET="_blank">NUCLEIC ACIDS RESEARCH; Sossou,M; 33(1):298-306 (2005)</A>]. Insofar as
the stages of DNA repair involve creation of AP sites and clipping of DNA strands, these
results should not be surprising. Enhanced DNA repair would require co-ordinated
increase in many enzymes.
<BR CLEAR=all>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Ultraviolet photoproducts</B></CAPTION>
<TR><TD WIDTH="350">
<img src="CPD_PP.jpg" width="350" height="250" alt="Ultraviolet photoproducts">
</TR></TD>
</TABLE>
<P><B>Nucleotide Excision Repair</B> (<B>NER</B>) repairs damage affecting more than one
nucleic acid base, defects which distort the DNA helix and can be exemplified by the
repair of cross-links between purines & the deoxyribose-phosphate backbone due to the
hydroxyl radical and by <B>pyrimidine dimers</B> (<b>CPD</b>s, Cyclobutane Pyrimidine Dimers,
two covalently-bonded adjacent pyrimidines, usually <b>thymine dimers</b>) caused by
ultraviolet light. Thymine-cytosine and cytosine-cytosine are the most mutagenic
CPDs [JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY; Marrot,L;
58(5 Suppl 2):S139-S148 (2008)]. Less frequently than CPDs, ultraviolet
light also induces 6−4 pyrimidine-pyrimidone photoproducts
(<b>6−4 PP</b>s). <b>CPD</b>s and <b>6−4 PP</b>s lead to
apoptosis [<A HREF="http://www.biomedcentral.com/1471-2407/5/135"
TARGET="_blank">BMC CANCER; Lo,H; 5:135 (2005)</A>] or double-strand
breaks [<A HREF="http://www.nature.com/emboj/journal/v24/n22/abs/7600849a.html"
TARGET="_blank">THE EMBO JOURNAL; Garinus,GA; 24(22):3952-3962 (2005)</A>]
if not repaired by NER. <A HREF="../health/cancer.html#chemicals"
TARGET="_blank">Carcinogen</A> lesions like those caused by aflatoxin (which forms bulky
DNA adducts) are also corrected by NER. <B>DNA polymerase delta</B> and <B>DNA polymerase epsilon</B>
are the specialized DNA polymerases used in NER. Many steps and more than 20 proteins are
involved in unwinding the DNA, in recognizing the type
of damage to be repaired, etc. NER provides backup to BER when glycosylases are defective in
the nucleus, but NER systems are absent from mammalian mitochondria (which only have BER).
A consequence of the fact that NER is so much more complex than BER is the fact that NER is more
error-prone than BER. A study of seven mammalian species showed a correlation between
both rate and extent of NER after UV exposure and lifespan of the
species [<A HREF="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=4526202"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Hart, RW;
71(6):2169-2173 (1974)</A>].
<BR CLEAR=all>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Nucleotide Excision Repair</B></CAPTION>
<TR><TD WIDTH="450">
<img src="NER.jpg" width="450" height="600" alt="Nucleotide Excision Repair">
</TR></TD>
</TABLE>
<P>There are two subtypes of NER, distinguished by how damage is recognized:
(1) <B>Global-Genome Repair</B> (<B>GGR</B>, recognizes damage throughout
the genome) and (2) <B>Transcription-Coupled Repair</B> (<B>TCR</B>, recognizes damage
by stalled transcription). The slower <B>GGR NER</B> (like all the DNA repair mechanisms
other than TCR) gradually covers the whole exposed genome. GGR recognizes strand
defects with <B>XP protein</B> — so-named because defects in these
<a href="http://en.wikipedia.org/wiki/Helicase" target="_blank">helicase</a> (DNA helix
unwinding) proteins (identified alphabetically from <b>XPA</b> to <b>XPG</b>) lead to the
disease known as <B>Xeroderma Pigmentosum</B>. The XP helicase unwinds DNA in the area
of the DNA damage so that other NER enzymes can make the repair. XPB & XPD are subunits
of <a href="http://en.wikipedia.org/wiki/Transcription_Factor_II_H"
target="_blank"><B>Transcription Factor IIH</B></a> (<B>TFIIH</B>), which functions in normal
transcription as well as in NER. <b>XPF−ERCC1</b> is an endonuclease wherein XPF is the
catalytic component and ERCC1 is required for DNA binding. <B>TCR NER</B> is a preferential
NER pathway focused on genes that are being transcribed. TCR ensures that DNA that is actively
being transcribed is given the highest priority for repair. Typically a TCR enzyme detects a
stalled RNA polymerase which is unable to proceed because of the DNA damage. The detection proteins
are called <B>CS proteins</B> because when they are defective the result is a disease known as
<B>Cockayne Syndrome</B>. CS proteins aid in displacement of the stalled RNA polymerase to
allow NER enzymes to access the damaged DNA. Then the XP helicase does the unwinding and
TCR NER then proceeds much as it would for global NER. The tumor-suppressor protein <B>BRCA1</B>
(which is often defective in
<A HREF="../health/cancer.html#breast" TARGET="_blank">breast cancer</A>) is essential
for TCR associated with oxidative DNA damage (but not with TCR associated with
ultraviolet light damage) [SCIENCE; Gowen,LC; 281:1009-1012 (1998)]. Defects in GGR lead to
cancer, whereas defects in TCR more readily lead to apoptosis ("accelerated
aging") [NATURE REVIEWS; Ljungman,M; 4(9):727-737 (2004)]. Nonproliferative
cells do not exhibit GGR, only exhibiting DNA repair on transcribed
genes [<A HREF="http://mcb.asm.org/cgi/content/full/20/5/1562"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; Nouspikel,T; 20(5):1562-1570 (2000)</A>
and <A HREF="http://mutage.oxfordjournals.org/cgi/content/full/21/1/49"
TARGET="_blank">MUTAGENESIS; Bielas,JH; 21(1):49-53 (2006)</A>].
<P><B>MisMatch Repair</B> (<B>MMR</B>) corrects errors made during DNA copying, such as
the mispairing of an adenosine base with a guanosine. MMR can correct A−C &
T−C mismatches more efficiently than G−A & T−C mismatches, and
does a very poor job of correcting C−C
mismatches [<A HREF="http://www.biochemj.org/bj/338/0001/bj3380001.htm"
TARGET="_blank">BIOCHEMICAL JOURNAL; Marra,J; 338(Pt 1):1-13 (1999)</A>].
But how do the recognition enzymes
know which is the correct base, the adenosine or the guanosine? For bacteria, the answer
is known: when DNA is freshly synthesized the parental strand has methyl groups
attached to certain adenosine residues, whereas the newly synthesized strand will be
unmethylated for some time after replication. Prior to methylation of the new strand
the detection enzymes can look for errors. DNA methylation is apparently not used for
error-detection in multi-cellular organisms, however, and the means of mismatch
detection is still unknown. Mismatch repair differs
from BER only in the first glycosylase, which recognizes and removes <B><I>mispaired</I></B>
bases — in contrast to BER which recognizes and removes <B><I>defective</I></B> bases. Removing
the mispaired base leaves an AP site which can then be repaired by the subsequent BER
enzymes. Failures in MMR result in mutations, whereas failures in BER result in
DNA damage (including mutations). Defects in MMR operation result in mutation rates 100−fold
greater than seen in normal cells, most often in
<a href="http://en.wikipedia.org/wiki/Microsatellite" target="_blank">microsatellite</a> sequences.
MMR corrects not only single base mispairs, but
Insertion/Deletion Loops (<B>IDL</B>s) that result from strand misalignments, which
can produce <B>frameshift mutations</B> (disrupted triplet codon reading due to
insertion or deletion of base pairs that is not a multiple of 3).
As well, MMR plays a significant role in protecting against
incorporation of 8−OHdG/8−oxoG into
DNA [<A HREF="http://mcb.asm.org/cgi/content/full/24/1/465"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; Russo,MT; 24(1):465-474 (2004)</A>].
<A HREF="../health/cancer.html#colon" TARGET="_blank">Hereditery
NonPolyposis Colon Cancer (HNPCC)</A> is often caused by defective <B>Msh2</B> protein,
which normally functions to recognize mispaired bases and to signal
MMR [<A HREF="http://www.jbc.org/cgi/content/full/277/10/8260"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Mazurek,AM; 277(10):8260-8266 (2002)</A>].
MMR also protects against cancer by inhibition of <B>ALT</B> (Alternative Lengthening of
Telomeres) [<A HREF="http://cancerres.aacrjournals.org/cgi/content/full/64/10/3444"
TARGET="_blank">CANCER RESEARCH; Bechter,OE; 64(10):344-3451 (2004)</A>].
<P>DNA repair enzymes exist for double-stand breaks and for guanine methylation, neither
of which involve excision of single DNA strands. Methylation of cytosine is a normal means
by which cells prevent gene expression. But methylation of guanine is DNA damage,
and deamination of a methylated cytosine results in thymine — a
mutation. A "suicidal" methyl transferase enzyme can repair
O<SUP>6</SUP>−methylguanine by transferring the methyl group to its own cysteine.
The DNA repair enzyme O<SUP>6</SUP>−<B>M</B>ethyl<B>G</B>uanine-DNA
<B>M</B>ethyl<B>T</B>ransferase (<B>MGMT</B>) is frequently repressed by hypermethylation
in colon cancer, which thereby allows alkylating agents to cause the <B>G:C</B>-to-<B>A:T</B>
conversions which are behind the <B>K−ras</B> mutation seen in about half of
<A HREF="../health/cancer.html#colon" TARGET="_blank">colorectal carcinomas</A>. MGMT can
remove not only methyl groups from guanine, but chloroethyl and benzyl groups. Because MGMT
corrects the nucleotide without removal, it is said to do repair by
<B>Direct Reversal</B> (<B>DR</B>).
<P><B>Double-Strand Breaks</B> (<B>DSBs</B>) normally occur during
<a href="http://en.wikipedia.org/wiki/V(D)J_recombination" target="_blank">V(D)J recombination</a>
and <a href="http://en.wikipedia.org/wiki/Meiosis" target="_blank">meiosis</a>
where <a href="http://en.wikipedia.org/wiki/Genetic_recombination" target="_blank">genetic
recombination</a> can be beneficial. Damaging DSBs are usually due to ionizing radiation
or very high doses of alkylating carcinogens such as nitrogen mustards. When the damage
is not so severe <b>Single-Strand Breaks</b> (<b>SSBs</b>) may result. Even with
ionizing radiation, double-strand breaks are only produced with about a tenth the frequency
of single strand breaks. Although double-strand breaks are rare, they are difficult
to repair and can be very injurious for somatic cells that undergo mitosis.
(The <a href="http://en.wikipedia.org/wiki/Deinococcus_radiodurans"
target="_blank">Deinococcus radiodurans</a> bacterium that lives in
nuclear reactors repairs double-strand damage very efficiently.) DSBs are repaired by
(1) <B>Non-Homologous End-Joining</B> (<B>NHEJ</B>) or (2) <B>Homologous Recombination</B>
(<B>HR</B>). NHEJ is the simplest and most common means of DSB repair, but it is the least
accurate. For NHEJ the two broken ends are rejoined without regard to deletions or
rearrangements. By contrast, HR exactly reconstitutes the original sequence of genes because
the sister chromatid (during <a href="http://en.wikipedia.org/wiki/Mitosis" target="_blank">mitosis</a>)
or homologous chromosome
(during <a href="http://en.wikipedia.org/wiki/Meiosis" target="_blank">meiosis</a>) is used.
But HR is limited by the fact that it can only operate during meiosis or late mitosis. NHEJ is
the only repair mechanism available for non-mitotic cells, whereas for mitotic cells NHEJ
operates in the G<sub>0</sub>, G<sub>1</sub> and early S phase of the
<a href="../health/cancer.html##cellcycle" target="_blank">cell cycle</a>, whereas HR
operates in late S phase and G<sub>2</sub>.
<p>DSBs are recognized by the <b>MRN complex</b> (composed of Mrell, Rad50 and Nbs1
proteins), which unwinds the DNA ends and recruits <b>ATM</b> protein to the
site of the break [SCIENCE; Lee,J; 308:551-554 (2005)]. ATM phosphorylates
<b>H2AX histone</b> (which recruits DNA repair proteins [SCIENCE; Celeste,A;
296:992-997 (2005)]) and <b>p53 protein</b> (which blocks progression
through the <A HREF="../health/cancer.html#cellcycle" TARGET="_blank">cell
cycle</A> leading to DNA repair or apoptosis — if DNA damage is too great
for available DNA-repair resources). ATM is responsible for phosphorylation of
Rad51 protein required for
HR [<A HREF="http://www.jbc.org/cgi/content/full/274/18/12748"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Chen,G; 274(18):12748-12752 (1999)</A>].
ATM regulates not only HR, but a more precise form of
NHEJ [<A HREF="http://cancerres.aacrjournals.org/cgi/content/full/66/3/1391"
TARGET="_blank">CANCER RESEARCH; Wang,H; 66(3):1391-1400 (2006)</A>].
<BR CLEAR=all>
<P><TABLE BORDER = "2" ALIGN=LEFT>
<CAPTION ALIGN=TOP><B>Non Homologous End-Joining for DSB Repair</B></CAPTION>
<TR WIDTH="700"><TD>
<img src="NHEJ.jpg" width="350" height="300" alt="Non Homologous End-Joining for DSB Repair">
</TD>
<TD>
<img src="NHEJ_2.jpg" width="350" height="300" alt="Non Homologous End-Joining for DSB Repair">
</TD></TR>
</TABLE>
<BR CLEAR=all>
<p>
<P> DSB repair is even more error-prone than NER, especially in the case of NHEJ.
The <B>WRN</B> protein, which is defective in <B>Werner's syndrome</B>, operates in DSB repair
by both NHEJ and HR [<A HREF="http://nar.oxfordjournals.org/cgi/content/full/35/22/7527"
TARGET="_blank">NUCLEIC ACIDS RESEARCH; Brosh,RM; 35(22):7527-7544(2007)</A>]. WRN protein
minimizes nucleotide loss during
NHEJ [<A HREF="http://cancerres.aacrjournals.org/cgi/content/full/62/2/547"
TARGET="_blank">CANCER RESEARCH; Oshima,J; 62(2):547-551 (2002)</A>]. Cells lacking WRN
may have such inefficient HR that they are dependent on forms of NHEJ for DSB
repair [<A HREF="http://genesdev.cshlp.org/content/15/8/933"
TARGET="_blank">GENES & DEVELOPMENT; Prince,PR; 15(8):933-938 (2001)</A>]. The
<B>Ku</B> protein heterodimer (Ku70/Ku86)
initiates NHEJ by binding to broken DNA ends and bringing them together. (Ku86 (mice?) is
sometimes called Ku80, but is actually
83 <a href="http://en.wikipedia.org/wiki/Atomic_mass_unit" target="_blank">kiloDaltons</a>.)
<B>Ku</B> heterodimers are so plentiful in mammalian nuclei that any DSB is likely to occur
within five molecular diameters of a <B>Ku</B> dimer. Both the <B>Ku</B> heterodimer
& the DNA-dependent Protein Kinase complex (<B>DNA−PKc</B>) bind to
WRN protein and regulate WRN
activity [<A HREF="http://www.jbc.org/cgi/content/full/277/21/18291"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Karmakar,P; 277(21):18291-18302
(2002)</A>]. WRN unwinds the DNA strands and then <B>Ku</B> attachment to WRN
strongly stimulates endonuclease activity in preparation for
ligation [<A HREF="http://carcin.oxfordjournals.org/cgi/content/full/24/5/791"
TARGET="_blank">CARCINOGENESIS; Opresko,PL; 24(5):791-802 (2003)</A>]. Overexpression
of <B>Ku</B> in normal yeast reduces gross chromosomal rearrangements, but <B>Ku</B> overexpression
increases gross chromosomal rearrangement in strains having a defective WRN
homolog [<A HREF="http://www.pnas.org/cgi/content/full/103/6/1816"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Banerjee,S;
103(6):1816-1821 (2006)</A>]. Ku86 and DNA−PKc are also important for telomere
maintenance [<A HREF="http://www.jcb.org/cgi/content/full/167/4/627"
TARGET="_blank">THE JOURNAL OF CELL BIOLOGY; Espejel,S; 167(4):627-638 (2004)</A>].
The nuclease <b>Artemis</b> processes damaged DNA ends prior to ligation
(rejoining) [<A HREF="http://www.landesbioscience.com/journals/cc/article/1527/"
TARGET="_blank">CELL CYCLE; Jeggo,PA; 4(3):359-362 (2005)</A>].
The tumor-suppressor protein <B>BRCA1</B> has also been shown to play a critical role in
NHEJ [<A HREF="http://hmg.oxfordjournals.org/cgi/content/full/12/suppl_1/R113"
TARGET="_blank">HUMAN MOLECULAR GENETICS; Deng,C; 12(1):R113-R123 (2003)</A>]. Although NHEJ is
"molecular guesswork" and very error prone, it is often effective because most of the
genome is composed of "junk DNA". One or more alternate forms of NHEJ exist, and
these alternate NHEJ forms are even more error-prone and mutagenic than primary
NHEJ [<A HREF="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000110"
TARGET="_blank">PLoS GENETICS; Bennardo,N;4(6):1-10(2008)</A>]. <b>Ku</b> protein has a
much higher affinity for DNA ends than PARP−1 does, but in the absence of <b>Ku</b>
PARP−1 will bind to DNA ends to provide a more error-prone "backup" form of
NHEJ [<A HREF="http://nar.oxfordjournals.org/cgi/content/full/34/8/2269"
TARGET="_blank">NUCLEIC ACIDS RESEARCH; Wang,M; 34(21):6170-6182 (2006)</A>].
<P><B>Homologous recombination</B> (<B>HR</B>, also called <B>REcombinational Repair</B>,
<B>RER</B>), a more
accurate but less frequently-used means of DSB repair, is the dominant method used in
the late S and G<SUB>2</SUB> phases of the cell-cycle, after a sister chromatid has
been created. Although HR is primarily restricted to repair of DSBs in proliferating
cells, even in proliferating cells 75% of DSBs are repaired by NHEJ [DNA REPAIR;
Mao,Z; 7(10):1765-1771 (2008)]. <b>ATR</b> (<b>AT</b>M and <b>R</b>ad3-related) checkpoint
protein facilitates HR [<A HREF="http://cancerres.aacrjournals.org/cgi/content/full/64/19/7139"
TARGET="_blank">CANCER RESEARCH; Wang,H; 64(19):7139-7143 (2004)</A>] and senses stalled
DNA replication forks [DNA REPAIR; Paulsen,RD; 6(7):953-966 (2007)], but ATR does
not facilitate NHEJ [<A HREF="http://cancerres.aacrjournals.org/cgi/content/full/64/19/7139"
TARGET="_blank">CANCER RESEARCH; Wang,H; 64(19):7139-7143 (2004)</A>]. (ATR is most active in
proliferative tissues.) In one form of HR (<b>synthesis-dependent strand annealing</b>) a single
DNA strand must associate with its complementary strand in a double-stranded DNA
molecule. In a simpler form of HR (<b>single-strand annealing</b>, which requires
fewer proteins) a single strand associates with its complementary single strand.
Homologous pairing of the sister chromatids is often mediated by <B>Rad51</B>
protein, which is normally necessary for cell proliferation and survival. <B>Rad52</B>
protein recognizes the DSB and adheres to the free ends of the break (comparable to
<b>Ku</b> in NHEJ) while <B>Rad51</B>
searches the undamaged sister chromatid for a homologous repair template. The tumor
suppressor protein <B>BRCA2</B> co-localizes with Rad51 during homologous recombinational
repair, and contributes significantly to its
activity [<A HREF="http://breast-cancer-research.com/content/3/5/294"
TARGET="_blank">BREAST CANCER RESEARCH; Orelli,BJ; 3(5):294-298 (2001)</A>]. HR could be
a basis for telomerase-independent telomere lengthening (ALT) in
mammals [<A HREF="http://embojournal.npgjournals.com/cgi/content/abstract/21/10/2383"
TARGET="_blank">THE EMBO JOURNAL; Blasco,MA; 24(6):1095-1103 (2005)</A>].
<BR CLEAR=all>
<P><TABLE BORDER = "2" ALIGN=LEFT>
<CAPTION ALIGN=TOP><B>Homologous Recombination (HR)</B></CAPTION>
<TR><TD WIDTH="700">
<img src="HR_steps.jpg" width="700" height="500" alt="Homologous Recombination (HR)">
</TR></TD>
</TABLE>
<BR CLEAR=all>
<p>
<p>For HR during
meiosis there can be a loss of information ("loss of
<a href="http://en.wikipedia.org/wiki/Zygosity" target="_blank">heterozygosity</a>")
if a <b>gene conversion</b> (replacement of two different
<a href="http://en.wikipedia.org/wiki/Allele" target="_blank">alleles</a> by the
same allele on both chromosomes) occurs.
<BR CLEAR=all>
<P><TABLE BORDER = "2" ALIGN=LEFT>
<CAPTION ALIGN=TOP><B>Homologous Recombination (HR) products</B></CAPTION>
<TR><TD WIDTH="700">
<img src="HR_prods.jpg" width="700" height="300" alt="Homologous Recombination (HR) products">
</TR></TD>
</TABLE>
<BR CLEAR=all>
<p>
<P><B>TransLesion Synthesis</B> (<B>TLS</B>) uses specialized DNA polymerases to quickly
patch damaged strands. Although more error-prone than BER, NER or MMR, TLS may reduce the
danger of DSBs [<A HREF="http://www.genesdev.org/cgi/content/full/16/15/1872"
TARGET="_blank">GENES & DEVELOPMENT; Prakash,S; 16(15):1872-1883 (2002)</A>].
<P>The bacterium <I>Deinococcus radiodurans</I> is the most radiation-resistant organism known.
Within one day of exposure to radiation inducing hundreds of DSBs the entire genome is
usually faithfully restored. The bacterium has a wide range of DNA repair enzymes and a
high amount of redundancy in the genes for those enzymes. With 4−10 copies of the entire
genome per cell, the polyploid bacterium has access to numerous templates for homologous
recombination [SCIENCE; White,O; 286:1571-1577 (1999)].
<P><b>Single-Strand Breaks</b> (<b>SSBs</b>) must be repaired quickly to prevent
them from becoming DSBs. An NAD-dependent enzyme named <b>Poly(ADP-Ribose) Polymerase−1</b>
(<b>PARP−1</b>) binds to SSBs and recruits
<a href="http://en.wikipedia.org/wiki/XRCC1" target="_blank">XRCC1</a> protein, which provides
the scaffold necessary for
<a href="http://en.wikipedia.org/wiki/DNA_polymerase_beta" target="_blank">DNA
polymerase β</a> to fill the
gap [<A HREF="http://www.nature.com/cr/journal/v18/n1/full/cr20087a.html"
TARGET="_blank">CELL RESEARCH; Horton,JK; 18(1):48-63 (2008)</A>]. In response to
single-strand DNA damage due to alkylating agents, oxidants or ionizing radiation,
levels of PARP−1 can increase several hundred-fold. Maximum lifespan in mammalian
species correlates with PARP
activity [<A HREF="http://www.pnas.org/cgi/content/abstract/89/24/11759"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Grube,K;
89(24):11759-11763 (1992)</A>]. PARP−1 modifies histones, transcription
factors and other nuclear regulatory proteins by addition of many ADP-ribose molecules to the
glutamic acid residues — increasing negative charge and thereby causing proteins to
unfold or become more open. PARP−1 addition of long ADP-ribose tails to histones can quickly
decondense chromatin to enable rapid transcription [SCIENCE; Pirrotta,V;
299:528-529 (2003)] and access for DNA repair [SCIENCE; Tulin,A; 299:560-562 (2003)]. The
ADP-riboses come from removing nicotinamide from NAD+ (<B>N</B>icotinamide <B>A</B>denine
<B>D</B>inucleotide). Poly (ADP-ribosyl)ation is a transient protein modification that is
rapidly reversed by poly (ADP-ribose) glycohyrolase. In addition to SSBs, PARP−1 functions
in BER and NHEJ to detect DNA damage and recruit DNA repair
enzymes [<A HREF="http://www.jbc.org/cgi/content/full/277/25/23028"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Schreiber,V; 23028-23036 (2002)</A>
and <A HREF="http://www.jbc.org/cgi/content/full/279/53/55117"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Audebert,M; 279(53):55117-55126
(2004)</A>], but may require the <B>WRN</B> protein to do
so [<A HREF="http://mcb.asm.org/cgi/content/full/23/23/8601"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; 23(23):8601-8613 (2003)</A>].
PARP−1 and WRN seem to interact in NHEJ as well as
BER [<A HREF="http://nar.oxfordjournals.org/cgi/content/full/35/22/7456"
TARGET="_blank">NUCLEIC ACIDS RESEARCH; Beneke,S; 35(22):7456-7465 (2007)</A>].
<P> Some protection against DNA damage is provided by gene redundancy. But
the only structural genes known to be present in multiple copies are those
coding for ribosomal RNA (rRNA), transfer RNA (tRNA) and histones. <B>Apoptosis</B>
(cell suicide) is the most effective defense against DNA damage & mutation
when DNA repair enzymes are inadequate to fix the damage. But p53 induction following UV
irradiation declines with age, as do levels of DNA repair
proteins [<A HREF="http://www.fasebj.org/cgi/content/full/14/10/1325"
TARGET="_blank">THE FASEB JOURNAL; Goukassian,D; 14(10):1325-1334 (2000)</A>]. The resultant
decline of DNA repair associated with decreased apoptosis for DNA damage can contribute
to cancer, and probably to aging.
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>rrr correlated with Maximum Life Span (MLS)</B></CAPTION>
<TR><TD WIDTH="400">
<img src="DNArepair.jpg" width="400" height="300" alt="Correlation of rat-relative repair (rrr)
and Maximum Life Span (MLS)">
</TR></TD>
<CAPTION ALIGN=BOTTOM><B>rrr = rat-relative repair (rat DNA−repair = = 1.0)</B></CAPTION>
</TABLE>
<P> The amount of oxidative DNA damage in neurons is likely to be many times
greater than in most other cells. The human brain accounts for only 2%
of total body weight, but 20% of resting oxygen consumption due to the
high metabolic demand required to maintain membrane ion potentials. Neurons
transcribe about 2−4 times as much DNA as do cells from kidney, liver
or spleen. Yet neurons are non-dividing and must last a lifetime.
<p>A profiling of gene expression for stem cells shows enriched expression of
DNA repair genes [SCIENCE; Ramalho-Santos,M; 298:597-600 (2002)].
<P> Even a "wear&tear" theory like DNA damage is subject to
a programmed aging interpretation. In general, DNA repair tends to lag behind DNA damage
to a greater extent in short-lived species, and the amount of lag can constitute the
degree of "programmed aging". A study which correlated maximum lifespan
in a variety of mammalian species found a six-fold difference in the nuclear DNA-repair
activity of mice and men. A graph of DNA-repair activity standardized on the
rat ("rat-relative repair", where rat DNA-repair activity equals 1.0),
showed a direct correlation between rat-relative DNA repair and maximum lifespan
for the species [MECHANISMS OF AGING AND DEVELOPMENT; Cortopassi, GA; 91:211-218 (1996)].
<P>Many of the nuclear DNA (<B>nDNA</B>) repair enzymes discussed above are the same as
or similar to the enzymes that repair mitochondrial DNA (<B>mtDNA</B>). The main deficiency
in mtDNA repair is the absence of NER enzymes/proteins, but the presence of multiple
copies of mtDNA in each mitochondrion compensates somewhat. The multiple genomes also
makes HR (homologous recombination) more feasible for mtDNA DSB repair.
<BR CLEAR=all>
<P><TABLE BORDER = "2" ALIGN=LEFT>
<CAPTION ALIGN=TOP><B>Comparison of mtDNA and nDNA Repair Enzymes/Proteins<B></CAPTION>
<TR><TD WIDTH="700">
<img src="DNArepairEnzymes.jpg" width="700" height="400"
alt="Comparison of mtDNA and nDNA Repair Enzymes/Proteins">
</TR></TD>
</TABLE>
<BR CLEAR=all>
<P>Because of the rapid turnover of mitochondria in cells, oxidative
damage to mitochondrial lipids (membranes) and proteins is normally less
of a concern than oxidative damage to mtDNA. But with age, lysosomes
become less efficient at removing defective mitochondria. Oxidative damage
to cardiolipin in the inner mitochondrial membrane reduces oxidative
phosphorylation [GENE; Paradies,G; 286(1):35-41 (2002)], which is
probably an important factor in the declining ATP production by
mitochondria associated with
aging [<A HREF="http://www.pnas.org/cgi/content/full/102/15/5618"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Short,KR; 102(15):5618-5623 (2005)</A>]. Moreover, the enzymes responsible
for importing DNA repair proteins into the mitochondria become increasingly
defective with age (possibly due to oxidative
damage) [<A HREF="http://www.pnas.org/cgi/content/full/100/19/10670"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Szczesny,B; 100(19):10670-10675 (2003)</A>].
<P>Healthy adults 65−80 years of age have about 25% higher skeletal
muscle mtDNA 8−oxodG than adults
20−35 [<A HREF="http://www.pnas.org/cgi/content/full/102/15/5618"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Short,KR; 102(15):5618-5623 (2005)</A>]. Oxidative damage to mtDNA leads
to mtDNA
deletions [<A HREF="http://www.ebmonline.org/cgi/content/full/227/9/671"
TARGET="_blank">EXPERIMENTAL BIOLOGY AND MEDICINE; Wei,Y; 227(9):671-682
(2002)</A>]. Clonal expansion of mtDNA deletions with age may ultimately
affect nearly all somatic mtDNA, leading to degenerative disease and the
aging phenotype [<A HREF="http://www.pnas.org/cgi/content/full/99/8/5521"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Nekhaeva,E; 99(8):5521-5526 (2002)</A>]. Even without oxidative damage mtDNA
mutations and deletions promote apoptosis, leading to tissue degeneration
and aging [SCIENCE; Kujoth,GC; 309:481-484 (2005)]. One mouse model of
"accelerated aging" is based on a mtDNA polymerase knockout that
leads to a 3−5 fold increase in point mutations, as well as to increased
mtDNA deletions [NATURE; Trifunovic,A; 429:417-423 (2004)].
<P><a href="#contents"> (return to contents)</a>
<BR CLEAR=all>
<H3><a name="telomeres">XII. TELOMERES AND AGING </a></H3>
<P>Animal cells can be classified as <B>germ cells</B> (sperm or egg),
<B>stem cells</B> (undifferentiated cells that can differentiate into
functioning body cells) and <B>somatic cells</B> (differentiated
functioning body cells). Somatic cells are either non-dividing after
birth (like neurons or muscle cells) or cells that continue to divide
(stem cells and most somatic cells).
<P> One of the most famous experiments in biogerontology was done by Leonard
Hayflick. He observed that embryonic fibroblasts (connective tissue cells)
in tissue culture would divide about 50 times before they ceased dividing.
This 50−division limit (the <B>Hayflick Limit</B>) seemed
to be a property of the cell nucleus or DNA.
<P> A human somatic or stem cell has 23 chromosome pairs
(46 chromosomes). Because each chromosome has two ends, there will
be 92 chromosome ends per cell. At the ends of each chromosome is
a long non-functional strand of DNA called a <B>telomere</B>. Telomeres
consist of the six-base repeating sequence TTAGGG (2 Thymines,
1 Adenine and 3 Guanines). With each cell division,
some of the telomere is lost because DNA polymerase cannot complete the
5'−end and therefore leaves a
<a href="http://www.mun.ca/biology/desmid/brian/BIOL2060/CellBiol17/CB17_14.html"
target="_blank">single-strand 3'−end overhang</a>. But the number of
times that most dividing cells can divide is limited by telomere length.
<P> At conception each human telomere is about 10,000 base pairs long (ie,
about 1,666 TTAGGG repeats), and the typical chromosome is about 13 thousand
times longer (130 million base-pairs). Nine months later, at birth, the
average telomere is half as long as it was at
conception. Telomeres lose an average of eight TTAGGG subunits per cell
division, so half of the telomere length was lost due to the cell
divisions of embryonic development. Human telomeres are less than half
as long as the telomeres of other primates — and the telomeres of
rodents are longer than those of primates [BIOCHEMICAL AND BIOPHYSICAL
RESEARCH COMMUNICATIONS 263:308-314 (1999)]. Telomeres shorten more
rapidly in short-lived mammals & birds than in long-lived
ones [PROCEEDINGS; BIOLOGICAL SCIENCES; THE ROYAL SOCIETY; Haussmann,MF;
270(1522):1387-1392 (2003)].
<P> For some species there is a correlation between maximum lifespan
and the number of fibroblast doublings for that species. Fibroblasts from different
species of mammals display a direct relationship between species lifespan and
number of populations doublings, from 8-11 in mice to 57-67 in
humans [<A HREF="http://www.pnas.org/cgi/content/abstract/78/8/5009"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Rohme,D;
78(8):5009-5013 (1981)</A>]. Among non-mammals, chickens with a
12−year lifespan show 25 doublings and the Galapagos tortoise with a
175−year lifespan shows 130 doublings. These species not only differ in initial
telomere length, but in the number of telomeres lost at each cell division. But if
maximum lifespan was determined by the Hayflick Limit alone, these species would have
a lifespan 2−3 times greater than what is observed. Mice have very long telomeres,
but have a very short lifespan — showing that long telomeres need not mean high
replicative capacity.
<a href="http://en.wikipedia.org/wiki/Drosophila_melanogaster" target="_blank">Flies</a> &
<a href="http://en.wikipedia.org/wiki/Caenorhabditis_elegans" target="_blank">nematodes</a> are
comprised entirely of post-mitotic (non-dividing) cells, which means telomeres are of
no relevance to lifespan in those species. Large animals tend to require more cell
divisions and also live longer, but this does not mean that a large number of divisions
causes longevity.
<P> For humans, the length of the remaining telomere is usually an indicator of how many
divisions a dividing cell has left. One study found an inverse relationship between
telomere length and pulse pressure, indicating a possible direct relationship between
vascular aging and telomere
length [<A HREF="http://hyper.ahajournals.org/cgi/content/full/36/2/195"
TARGET="_blank">HYPERTENSION; Jeanclos,E; 36(2):195-200 (2000)</A>].
Higher levels of oxidative stress increase the rate
of telomere shortening [TRENDS IN BIOCHEMICAL SCIENCES 27(7):339-344 (2002)].
Once the telomere is gone, functional genetic DNA would be lost with each cell
division. Prior to complete erosion of the telomere a signal is sent to p53 protein
(possibly by ATM protein) to stop the <A HREF="../health/cancer.html#cellcycle"
TARGET="_blank">cell cycle</A> causing the cell to go into a slow-decaying,
non-replicative state known as <B>replicative senescence</B>. Telomeres protect chromosomes
like the plastic cap that prevents shoe-laces from becoming frayed at the ends. Telomeres
have been shown to be seven times more vulnerable to hydroxyl radical oxidation than
similar-sized DNA control fragments, indicating that telomeres could sacrificially protect
coding DNA from oxidative damage [<A HREF="http://www.jbc.org/cgi/content/full/274/2/962"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Henle,ES; 274(2):962-971 (1999)</A>].
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Telomere Complex</B></CAPTION>
<TR><TD WIDTH="500">
<img src="telomere.jpg" width="500" height="300" alt="Telomere Complex">
</TR></TD>
</TABLE>
<P>Telomeres are actually a loop-like structure which is associated with an assortment
of proteins (the <b>shelterin complex</b>), the most notable of which are the
<B>Telomeric Repeat-binding Factors</B>
(<B>TRF</B>s). <B>TRF1</B> regulates telomere length, assisting the telomerase
enzyme. <B>TRF2</B> models the telomere into the <B>T−loop</B> structure. TRF2
may be protecting the single-stranded 3'−end overhang from degradation, and
by binding to ATM prevents the ATM-dependent DNA damage
response [<A HREF="http://embojournal.npgjournals.com/cgi/content/abstract/21/10/2383"
TARGET="_blank">THE EMBO JOURNAL; Blasco,MA; 24(6):1095-1103 (2005)</A>]. Loss of
TRF2 from telomeres directly signals apoptosis [SCIENCE; Karlseder,J;
283:1321-1325 (1999)]. TRF2 stimulates the helicase activity of both <B>WRN</B> (of
Werner's Syndrome) and <B>BLM</B> (of Bloom Syndrome), which may play a role in telomere
maintenance [<A HREF="http://www.jbc.org/cgi/content/full/277/43/41110"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Opresko,PL; 277(43):41110-41119
(2002)</A>]. <B>Ku proteins</B> (normally active in double-strand
break repair) prevent aberrant telomere-telomere fusions. <B>Tankyrase</B> is a
<B>PARP</B> — Poly (Adenosine diphosphate-Ribose) Polymerase — which can ADP-ribosylate
TRF1, thereby removing it from DNA and allowing telomerase lengthening of the
telomere [SCIENCE; Pirrotta,V; 299:528-529 (2003)]. TRF2 is regulated by
PARP−2 [<A HREF="http://mcb.asm.org/cgi/content/full/24/4/1595"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; Dantzer,F; 24(4):1595-1607 (2004)</A>].
<P> Germ cells, stem cells and "immortalized" cancer cells contain an enzyme
called <B>telomerase</B> that replaces lost telomeres, thus preventing them
from experiencing a Hayflick Limit.
Telomerase is a <B>reverse transcriptase</B>, meaning an enzyme that makes DNA
from an RNA template (the reverse of normal transcription which uses DNA as the
template for making RNA). In human germ cells or 85% of cancer cells
<B>h</B>uman <B>TE</B>lomerase <B>R</B>everse <B>T</B>ranscriptase (<B>hTERT</B>)
and an RNA template are sufficient conditions for the creation of new telomeres. Because
most cells normally express the RNA template, derepression of hTERT is the critical step
for acquiring telomerase activity. Defects in proteins required to maintain telomere
function can also lead to chromosome instability and cancer [EXPERIMENTAL GERONTOLOGY
36:1619-1637 (2001)]. Telomerase expression can actually make cells more resistant to
apoptosis induced by oxidative stress [FEBS LETTERS; Ren,J; 488:133-138 (2001)].
<P>Mice show no reduction of somatic cell telomere length with age [NATURE 347:400-402 (1990)]
thanks to active somatic telomerase [SCIENCE 291:872-875 (2001)]. Telomeres in
mouse stem cells do, however, shorten with age, possibly leading to decreased regenerative
capacity [<A HREF="http://genesdev.cshlp.org/content/22/5/654.long"
TARGET="_blank">GENES & DEVELOPMENT; Flores,I; 22(5):654-667 (2008)</A>].
Despite the apparent absence of somatic cell telomere shortening, most
mouse somatic cells stop dividing after only 10−15 doublings.
Possibly, in spite of the ultra-long
telomeres on most chromosomes, a single chromosome with a short telomere could induce
senescence [<A HREF="http://www.pnas.org/cgi/content/full/94/14/7423"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Mark,J;
94(14):7423-7428 (1997)</A>]. But mouse cells can become senescent despite being
telomerase-positive. Nonetheless, transgenic mice with constitutively expressed TERT
and enhanced expression of tumor-suppressor genes (to provide cancer resistance) have
shown extended mean lifespan and reduced signs of aging [CELL; Tomas-Loba,A;
135(4):609-622 (2008)]. A study of 15 rodent species showed an inverse relationship
between telomerase activity and body mass, but no relationship between telomerase
activity and lifespan [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527635/"
TARGET="_blank">AGE; Gorbunova,V; 30(2-3):111-119 (2008)</A>].
<P>Telomerase knockout mice (mice for whom the telomerase gene has been removed
or "knocked-out") can sometimes maintain telomere length by a mechanism
known as <B>A</B>lternative <B>L</B>engthening of <B>T</B>elomeres (<B>ALT</B>).
ALT can also occur in a human cell, but it is ten million times more likely to
occur in a mouse cell [NATURE MEDICINE 6(8):849-851 (2000)]. ALT may be induced by
p53 perturbations at
telomeres [<A HREF="http://mcb.asm.org/cgi/content/abstract/24/13/5967"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; Zaineb,R; 24(13):5967-5977 (2004)</A>]
or related to DNA repair at the site of the telomere.
<p><b>PML bodies</b> are donut-shaped protein aggregates in the nucleus containing
<b>PML</b> (ProMyelocyclic Leukemia) protein along with other proteins such as pRb.
PML bodies are suspected to normally play a role in tumor suppression. But in
immortalized telomerase-negative ALT cells an aberrant form of PML bodies occur
which contain telomeric DNA, telomere-binding proteins TRF1 & TRF2 and the
Rad51 & Rad52 proteins that are normally active in homologous recombination repair
of double-stranded DNA
breaks [<A HREF="http://cancerres.aacrjournals.org/cgi/content/full/59/17/4175"
TARGET="_blank">CANCER RESEARCH; Yeager,TR; 59(17):4175-4179 (1999)</A>].
Extrachromosomal telomeric repeats found in the PML bodies can serve as templates
for homologous recombination of
telomeres [<A HREF="http://cancerres.aacrjournals.org/cgi/content/full/59/17/4175"
TARGET="_blank">CANCER RESEARCH; Yeager,TR; 59(17):4175-4179 (1999)</A>].
<P> If cells continue to divide after having lost their telomeres
(ie, beyond the Hayflick Limit of about 50 cell divisions),
they not only become malfunctional due to lost genes, but the
chromosome ends start sticking to other chromosomes — increasing the
number of abnormalities. Typically a cell will invoke apoptosis
("cell suicide") or other or become senescent (stop the
cell cycle) to prevent the cell from dividing or
becoming cancerous. The Hayflick Limit itself may be a means of
preventing cancer [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/16081723"
TARGET="_blank">SCIENCE; Campisi,J; 309:886-887 (2005)</A>].
<P> For those who believe that telomeres are a biological clock
that cause aging by shortening, there has been the hope that human
aging can be stopped by somehow adding active telomerase to all
somatic cells. An experiment transfected human somatic cells
with a reverse transcriptase subunit of telomerase thereby forcing the
cells to express telomerase. The cells exhibited 20 population
doublings beyond their Hayflick Limit and continued to exhibit normal,
healthy and youthful cellular appearance & activity. This experiment
was done not only for fibroblasts, but for retinal epithelial cells and
vascular endothelial cells [SCIENCE 279:334&349 (1998)]. This result
creates hope that it may someday be possible to preserve youth in some tissues by a form of
gene therapy that either induces the expression of telomerase in somatic
cells or adds additional genetic material to cells consisting of an
engineered telomerase superior to the natural form. A person undergoing
such therapy might first take a dose of telomerase destroyers to prevent
any incipient cancers from being nourished by the treatment that would
follow.
<P> Nonetheless, only a few tissues that rapidly proliferate (endothelial cells,
immune system cells, etc.) show decreased function with age that could be associated
with telomere shortening. It is no accident that the notable exceptions to the rule
of lack of telomerase in normal somatic cells are immune system
cells [<A HREF="http://www.pnas.org/cgi/content/abstract/92/20/9082"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Broccoli,D;
92(20):9082-9086 (1995)</A>] and endothelial
cells [<A HREF="http://circres.ahajournals.org/cgi/content/full/87/7/540"
TARGET="_blank">CIRCULATION RESEARCH; Vasa,M; 87(7):540-542 (2000)</A>].
For endothelial cells, the exhaustion of replicative capacity
is greatest in areas of atherosclerosis — where the rate of cell division has been
accelerated [<A HREF="http://www.pnas.org/cgi/content/abstract/92/24/11190"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA)92(24):11190-11194
(1995)</A>]. Telomere erosion contributes to defective liver regeneration and accelerated
cirrhosis in chronic liver injury [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/10678830"
TARGET="_blank">SCIENCE; Rudolph,KL; 287:1253-1258 (2000)</A>].
<p>In one study, for a sample of 143 normal people over age 60 having
shorter telomeres the chance of death was more than 3 times greater than average for
heart disease and more than 8 times graater for infectious diseases, but there was
no increased risk for cancer [THE LANCET; Cawthon,RM; 361:393-395 (2003)]. For
males, telomere erosion has been correlated with unhealthy, pro-aging habits such
as smoking, waist circumference, low physical activity and low fruit/vegetable
intake [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/17874998"
TARGET="_blank">AGING CELL; Bekaert,S; 6(5):639-647 (2007)</A> and
<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/17725691"
TARGET="_blank">AGING CELL; Huda,N; 6(5):709-713 (2007)</A>]. Rate of
telomere shortening has predicted cardiovascular mortality in the
elderly [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830080/"
TARGET="_blank">AGING; Epel,ES; 1(1):81-88 (2008)</A>]. A study of 175 elderly Swedish
twin-pairs found that the twins with the shortest telomeres (75% of the cohort)
had 3 times the risk of death compared to the 25% with the longest
telomeres [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/17925004"
TARGET="_blank">AGING CELL; Bakaysa,SL; 6(6):769-774 (2007)</A>].
Other studies show no relationship between telomere length and morbidity or mortality
in the elderly [AGING CELL; Martin-Ruiz,CM; 4(6):287-290 (2005) and EPIDEMIOLOGY;
Bischoff,C; 17(2):190-194 (2006)].
<p>People don't age or die because their cells aren't dividing. Cells in culture do
not die after they cease dividing — and may survive as well as cells that never divide,
such as neurons & muscle cells.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="senescence">XIII. CELLULAR SENESCENCE AND APOPTOSIS IN AGING </a></H3>
<P> For background on cell cycle function, read
<A HREF="../health/cancer.html#cellcycle" TARGET="_blank">Cell Cycle Control</A>
and <A HREF="../health/cancer.html#signalling" TARGET="_blank">Signalling Molecules
and Transcriptions Factors</A>.
<P> The relationship between cellular aging and the aging of the
whole organism is complex. Cellular "immortality" is
essential for stem cells, but an "immortal" somatic cell
is cancerous.
<a href="http://en.wikipedia.org/wiki/Apoptosis" target="_blank"><B>Apoptosis</B></a>
(sometimes pronounced ap-ah-TOE-sis — the second
"p" is silent) is programmed cell suicide — a genetically
<B><I>controlled cell death</I></B> that causes cells to shrink and be eliminated
without the tissue traumas associated with inflammation that accompanies
<B><I>uncontrolled cell death</I></B> (<a href="http://en.wikipedia.org/wiki/Necrosis"
target="_blank"><b>necrosis</b></a>). Whether a cell dies by apoptosis or necrosis
is critically dependent upon the presence or absence of
ATP [<A HREF="http://www.jem.org/cgi/content/full/185/8/1481"
TARGET="_blank">JOURNAL OF EXPERIMENTAL MEDICINE; 185(8):1481-1486 (1997)</A>].
Apoptosis can benefit
the organism by eliminating defective cells and protecting from
cancer — or be associated with harmful conditions, as in
atherosclerosis and neurogenerative disease. Cellular senescence
(permanent cell cycle arrest) can benefit the organism by reducing
vulnerability to cancer, but may also contribute to aging-associated
tissue deterioration.
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<TR><TD WIDTH="400">
<img src="TNFp53.jpg" width="400" height="400"
alt="Cytochrome−c activates apoptosis">
</TR></TD>
</TABLE>
<P>In apoptosis proteolytic enzymes (notably <B>caspases</B> — <B>C</B>ysteine
<B>AS</B>partase <B>P</B>rote<B>ASES</B>) begin the process of orderly protein
degradation that culminates in the production of small packages of cellular remnant.
Apoptosis initiated by an extracellular signal (Fas receptor) activates
<B>caspase 8</B>, whereas apoptosis due to intracellular damage or distress
activates <B>caspase 9</B>. Both caspase 8 and caspase 9 are initiator
caspases which can activate <b>caspase 3</b>, the primary effector caspase which
induces apoptosis [JOURNAL OF NEUROCHEMISTRY; Polster,BM; 90(6):1281-1289 (2004)].
<p>The tumor-suppressor protein <B>p53</B> can be a potent initiator
of apoptosis, whereas anti-apoptotic
<B>Bcl−2</B> is an oncogene because mutations in the gene increase
<B>Bcl−2</B> protein expression, thereby protecting cancer cells from apoptosis.
There is a "family" of <b>Bcl−2</B> proteins, all of which possess
at least one of four <B>B</B>cl−2 <b>H</b>omology domains (<b>BH1</b> to <b>BH4</b>).
The anti-apoptosis subfamily (which includes <B>Bcl−2</B>, <B>Mcl−1</B> and
<B>Bcl−x<sub>L</sub></B>) have all of the homology domains, whereas the
pro-apoptotic subfamily (<B>Bax</B>, <B>Bak</B>, <B>Bad</B>, <B>Bim</B>, <B>Bid</B>, <B>Bik</B>,
<B>PUMA</B>, <B>Noxa</B>, etc.) are all missing <B>BH1</B>. <B>Bim</B>, <B>Bad</B>,
<B>Bid</B>, <B>PUMA</B> and <B>Noxa</B> only contain
<B>BH3</B> [SCIENCE; Adams,JM; 281:1322-1324 (1998)]. In response to DNA damage,
<b>PUMA</b> (<b>p</b>53 <b>U</b>pregulated <b>M</b>ediator of <b>A</b>poptosis) mediates
<b>Bax</b> translocation to the
mitochondria [<A HREF="http://www.jbc.org/cgi/content/full/279/9/8076"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Melino,G; 279(9):8076-8083
(2004)</A>]. In response to DNA damage p53 protein can induce apoptosis by increasing
transcription of <B>BH3</B>-only proteins [SCIENCE; Villuger,A;
302:1036-1038 (2003)]. Anti-apoptotic members of the <B>Bcl−2</B>
family stabilize the outer mitochondrial membrane (preventing cytochrome−c
release) whereas pro-apoptotic members increase permeability of the outer
mitochondrial
membrane [<A HREF="http://www.biomedcentral.com/content/pdf/1471-2121-2-22.pdf"
TARGET="_blank">BMC CELL BIOLOGY; Lutter,M; 2:22-30 (2001)</A>]. <B>Bax</B> and <B>Bak</B>
are restrained from permeabilizing the mitochondrial membrane by their association with
the anti-apoptotic subfamily proteins. The <B>BH3</B>-only proteins promote apoptosis by
interfering with the association of the anti-apoptotic subfamily proteins with
<B>Bax</B> and <B>Bak</B> [SCIENCE; Willis,SN; 315:856-859 (2007)], and (in the case
of <b>Bid</b> & <b>Bim</b>) by directly activating <b>Bax</b> & <b>Bak</b>) [NATURE;
Gavathiotis,E; 455:1076-1081 (2008)].
<p>If intracelluar Ca<SUP>2+</SUP> is high, <B>p53</B> may be bypassed because high mitochondrial
Ca<SUP>2+</SUP> opens the
<a href="#MPTP" target="_blank">Mitochondrial Permeability Transition Pore (<B>MPTP</B>)</a>
causing energy uncoupling (reduced inner membrane proton gradient), increased superoxide
production, reduced ATP production and the release of <B>cytochrome c</B> to the
cytosol — which activates caspase 9. Caspase 9 activates caspase 3 and
caspase 7 by forming an <b>apoptosome</b> with cytochrome−c and Apoptotic
Protease Activating Factor−1 (APAF−1). Oxidative stress, DNA damage
and cell stress other than high Ca<sup>2+</sup> may induce <b>Bid</b> protein to
form <b>Bax/Bak</b> channels and release of
cytochrome−c [<A HREF="http://www.jbc.org/cgi/content/full/279/14/13575"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Rostovtseva,TK; 279(14):13575-13583
(2004)</A>].
<br clear=all>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>MAPK families and AP−1</B></CAPTION>
<TR><TD WIDTH="300">
<img src="MAPKs.jpg" width="300" height="200" alt="MAPK families and AP−1">
</TR></TD>
</TABLE>
<P><B>Mitogens</B> are agents that trigger mitosis (cell division). Growth factors
are mitogens, but stress can be mitogenic as well. Although very active cell proliferation
(mitosis) is essential to growth & development in a young organism, in an older organism
proliferation may often be associated with inflammation. Proliferation in older animals
more easily leads to cancer (short-lived invertebrates usually have post-mitotic cells).
Mitogens generally act at cell surfaces, and cell signalling resulting from surface
stimulation is by <B>Mitogen Activated Protein Kinases</B> (<B>MAPKs</B>). (A <B>kinase</B>
is an enzyme that transfers a phosphate group from ATP, GTP, ADP, etc, to an enzyme,
thereby activating the enzyme. A <B>phospatase</B> does the opposite, inactivating enzymes
by removing a phosphate group.) <B>MAPK</B> pathways are typically a series of kinases
that activate other kinases.
<P>There are three families of <B>MAPKs</B>: (1) Extracellular signal-Regulated
Kinases (<B>ERKs</B>), (2) c−Jun N−terminal Kinases (<B>JNKs</B>) and
(3) the <b>p38</b> family of kinases. The <B>ERK</B> family responds to growth factors, resulting
in proliferation & differentiation, whereas the other two families respond to a
variety of stresses or inflammatory cytokines that can lead either to apoptosis or to
proliferation — depending on the tissue & stimulation. The most important inflammatory
kinase is <B>p38</B>. Activator Protein−1 (<B>AP−1</B>, a regulator of cell survival
and proliferation) is a transcription factor activated by either <B>ERK</B> or <B>JNK</B>.
<B>AP−1</B> can be pro-apoptotic or anti-apoptotic, but is most often anti-apoptotic
(in association with DNA-repair). ATM loss leads to JNK-mediated <B>AP−1</B>
stress [<A HREF="http://www.jbc.org/cgi/content/full/278/9/6741"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Weizman,N; 278(9):6741-6747 (2003)</A>].
<P><B>Senescent cells</B> (cells that no longer proliferate or divide
in response to growth factors or mitogens) can function like
normal cells, but display a number of distinctive characteristics.
Some of these characteristics, such as increased free radical production,
increased oxidative damage, increased glycation damage and reduced
heat shock protein expression may simply be due to the fact that
senescent cells are usually "old". Senescent cells completely lack
<b>H1</b> histone (the histone which causes second-order compacting
of chromatin) and contain transcriptionally silent heterchromatic foci
which are believed to repress proliferation
genes [<A HREF="http://jcb.rupress.org/cgi/content/full/175/6/869"
TARGET="_blank">JOURNAL OF CELL BIOLOGY; Funayama,R; 175(6):869-880 (2006)</A>].
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Ras/Raf/MEK/ERF Pathway</B></CAPTION>
<TR><TD WIDTH="400">
<img src="RasPath.jpg" width="400" height="500" alt="Ras/Raf/MEK/ERF Pathway">
</TR></TD>
</TABLE>
<P>But the accumulation of
defective proteins may be partially due to a genetic
down-regulation of proteasome activity associated with the senescent
phenotype [<A HREF="http://www.jbc.org/cgi/content/full/278/30/28026"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Chondrogianni, N;
278(30):28026-28037 (2003)</A>]. Although Growth Factors (<B>GF</B>s) can still activate the
Ras/Raf/MEK/ERK pathway in senescent cells, the <B>ERK</B> subgroup of <B>MAPKs</B>
fail to enter the nucleus, <I><B>c−fos</I></B> induction
is reduced and Activator Protein−1 (<B>AP−1</B>) transcription factor is far less
capable of binding to DNA. AP−1 activity as a regulator of cell survival —
proliferation is highly influenced by the AP−1
consitituents [<A HREF="http://jcs.biologists.org/cgi/content/full/117/25/5965"
TARGET="_blank">JOURNAL OF CELL SCIENCE; Hess,J; 117(Pt 25); 5965-5973 (2004)</A>].
Depending on the influence of other transcription factors,
<B>c−fos</B> can cause cellular proliferation, differentiation or apoptosis. Serum
Response Elements (<B>SRE</B>s) regulate </B>c−fos</B> expression, which is
activated by the Ternary Complex Factor (<B>TCF</B>) transcription factors
that cannot bind to SRE without Serum Response Factor (<B>SRF</B>). The
<B>c−Jun</B> protein is activated by the Jun Kinase (<B>JNK</B>) MAPKs. JNK activity
is most stimulated by UV light, whereas ERKs are most strongly stimulated by growth
factors [<A HREF="http://www.jbc.org/cgi/content/full/270/28/16483"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Karin,M; 270(28):16483-16486 (1995)</A>].
Increased expression of c−Jun due to ultraviolet light leads to AP−1
induction of metalloproteinases (collagenases) that contribute to "photoaging"
of skin [<A HREF="http://www.jci.org/cgi/content/full/101/6/1432"
TARGET="_blank">JOURNAL OF CLINICAL INVESTIGATION; Fisher,GJ; 101(6):1432-1440 (1998)</A>].
<P>Senescent cells are resistant to apoptosis, unlike the postmitotic neurons that
apoptotically contribute to neurodegeneration. Senescent cells are not only
more sensitive to cell injury, they have larger nuclei and less regular
shape. Senescent fibroblasts secrete metalloproteinases that degrade the
collagen matrix secreted by normal fibroblasts. Senescent fibroblasts
also secrete inflammatory cytokines, such as InterLeukin−1 (IL−1).
<P>Resistance of aging cells to apoptosis may be due to a decline in apoptotic protein
function rather than cell senescence [NATURE MEDICINE; Suh,Y; 8(1):3-4 (2002)].
<A HREF="../calories/calories.html" TARGET="_blank">Caloric Restriction with Adequate
Nutrition</A> (CRAN) increases rat liver cell apoptosis, particularly for pre-cancerous
cells [<A HREF="http://www.pnas.org/cgi/content/abstract/91/21/9995"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA) 91(21):9995-9999
(1994)</A>]. Normally reduced proteolysis by proteasomes allows p53 accumulation to
induce apoptosis [<A HREF="http://www.jbc.org/cgi/content/full/272/20/12893"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Lopes,UG; 272(20):12893-12896 (1997)</A>],
but the mechanisms become more dysfunctional with aging. In senescent cells proteasome
activity declines even more rapidly, resulting in a faster accumulation of undegraded
protein products [<A HREF="http://www.fasebj.org/cgi/content/full/14/15/2495"
TARGET="_blank">THE FASEB JOURNAL; Sitte,N; 14(15):2495-2502 (2000)</A>].
<P>One could easily imagine that the accumulation of increasing numbers
of senescent cells within tissues would contribute to aging of tissues
& organs. Although this appears to be the case in diabetics and
progeria victims (Werner's Syndrome, Down's Syndrome and childhood
progeria), it has not been demonstrated for fibroblasts of "healthy"
persons [<A HREF="http://www.pnas.org/cgi/content/full/95/18/10614"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Cristofalo,VJ;
95(18):10614-10619 (1998)</A>]. Only a
minority of fibroblasts are senescent in the healthy elderly. On the other
hand, cellular senescence may play a critical role in aging endothelial
cells and the development of
atherosclerosis [<A HREF="http://www.pnas.org/cgi/content/abstract/92/24/11190"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Chang,E;
92(24):11190-11194 (1995)</A>] and in T−cells.
<P>In mammals, shortening of telomeres leads to senescence in some cells
(<i>e.g.</i>, fibroblasts) and apoptosis in other cells (<i>e.g.</i>,
T−cells) [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/10037601"
TARGET="_blank">SCIENCE; Karlseder,J; 283:1321-1325 (1999)</A>].
The ATM protein kinase which activates p53 protein in response to DNA damage also
activates p53 in response to telomere shortening. Inhibition of ATM in DNA damage
conditions leads to reduced cell senescence and increased
apoptosis [<A HREF="http://www.jbc.org/cgi/content/full/280/20/19635"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Zhang,X; 280(20):19635-19640
(2005)</A>]. Other proteins which participate in NHEJ of double-strand break (DSB)
repair assist in apoptosis induction if DSB repair fails [CELL SIGNALLING;
Abe,T; 20(11):1978-1985 (2008)]. The cell cycle is halted by
<B>p21<SUP>Cip1</SUP></B> protein (activated by p53), which initiates cell senescence. But p21
is only expressed transiently. Long-term maintenance of cellular senescence requires
expression of the cell cycle inhibitor <B>p16<SUP>INK4a</SUP></B> protein, which
is also induced by p53.
<p>A study of rodent organs found an average 10-fold increase in p16<sup>INK4a</sup>
expression and an average of 3.5-fold increase in <b>Arf</b> expression with age,
concluding that these proteins are biomarkers — and possible effectors —
of both cellular senescence and of mammalian
aging [<A HREF="http://www.jci.org/articles/view/22475"
TARGET="_blank">JOURNAL OF CLINICAL INVESTIGATION; Krishnamurthy,J;
114(9):1299-1307 (2004)</A>]. Increased p16<sup>INK4a</sup> expression
with age may lead to increased senescence of pancreatic β−cell
stem cells in non-insulin-resistant type 2
diabetes [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/16957737"
TARGET="_blank">NATURE; Krishnamarthy,J; 443:453-457 (2006)</A>]
— and increased stem cell senescence associated with declining neurogenesis
in some (but not all) areas of the brain [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/16957738"
TARGET="_blank">NATURE; Molofsky,AV; 443:448-452 (2006)</A>].
In human T-lymphocytes, p16<sup>INK4a</sup> expression increases
with age between ages 20 to 80, with twice the increase in
smokers [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/19485966"
TARGET="_blank">SCIENCE; Liu,Y; 8(4):439-448 (2009)</A>]. Removal
of p16<sup>INK4a</sup>-positive senescent cells in mice delayed
the onset of age-related pathologies [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/22048312"
TARGET="_blank">NATURE; Baker,DJ; 479:232-236 (2011)</A>].
Mice that were transgenic with extra genes of both p53 and <b>Arf</b> (with normal activity
of both) had strong cancer resistance, increased levels of reduced glutathione (GSH)
antioxidant, and lifespan increase of 16% [NATURE; Matheu,A; 448:375-380 (2007)].
<p>Both p16 and p21 act by reducing pRB phosphorylation, thereby preventing expression
of the EF2 transcription factors required for DNA synthesis. Nonetheless,
the p53 and pRb tumor-suppressor proteins make partially independent contributions to
cellular senescence. Exposure of the telomere
<a href="http://www.senescence.info/telomeres.html" target="_blank">3' overhang</a>
after telomere loop disruption appears to be the critical signal for replicative senescence
because oligonucleotides with this overhang can induce senescence in
fibroblasts [<A HREF="http://www.pnas.org/cgi/content/full/100/2/527"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Li,G;
100(2):527-531 (2003)</A>].
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Cell Divisons and Cell Senescence</B></CAPTION>
<TR><TD WIDTH="400">
<img src="M1M2.jpg" width="400" height="300" alt="Cell Divisons and Cell Senescence">
</TR></TD>
</TABLE>
<P>In normal human cells, telomere shortening (typically 50−200 base pairs lost per cell
division) will induce cellular senescence after between
50 to 100 cell divisions (<B><I>in vitro</I></B> population doublings),
depending on the cell type. Normal cellular senescence is designated <B>M1</B> (<B>Mortality
Stage 1</B>). If either p53 or pRb expression is inhibited (eg, through defective genes),
senescence will occur after about ten additional population doublings. If both p53 and pRb
expression is inhibited (eg, by simian virus 40, <B>SV40</B>), then about twenty
additional doublings will occur and cells enter <B>M2</B> (<B>Mortality
Stage 2</B>), also called <B>crisis</B>. In contrast to M1 cells (which have short
telomeres of about 4 Kbp, Kilobase pairs), M2 cells have extremely short telomeres
(about 1.5 Kbp), are genetically unstable and usually die quickly [THE EMBO JOURNAL;
Counter,CM; 11(5):1921-1929 (1992)]. Fewer than one in a million cells survive crisis.
Surviving cells nearly always become "immortalized" by telomere expression.
<P>(In contrast to humans, although rats display senescence for fibroblasts, they show no
sign of replicative senescence for glial cells [SCIENCE; Mathon,NF; 291:872-875 (2001)].)
<P>So-called premature cellular senescence can be provoked by various sublethal cellular stresses
such as hydrogen peroxide, ultraviolet irradiation and similarly damaging agents which either
accelerate the number of telomeres lost per division or directly induce DNA damage or both.
Fenton reaction-mediated DNA damage is seven times more likely to occur in telomeres than
elsewhere in a chromosome, probably because of the higher proportion of
guanosines in the telomere
(TTAGGG) [<A HREF="http://www.jbc.org/cgi/content/full/274/2/962"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Henle,ES; 274(2):962-971 (1999)</A>].
In fact, the role of oxidation in telomere shortening is dramatically demonstrated by
the fact that spin-trapping agent PBN treatment of cells can increase their number of
population doublings by as much as
25% [<A HREF="http://www.pnas.org/cgi/content/abstract/92/10/4337"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Chen,Q;
92(10):4337-4341 (1995)</A>].
<P> But premature cellular senescence can also be induced by agents that are more directly
involved in cell signalling dysfunction, such as <B><I>ras</I></B> oncogene
overexpression [CELL; Serrano,M;88(5):593-602 (1997)], PML protein
overexpression [THE EMBO JOURNAL; Bischof,O; 21(13):3358-3369 (2002)], Transforming
Growth Factor beta (<b>TGF−ß</b>) or histone deacetylase
inhibition [<A HREF="http://mcb.asm.org/cgi/content/abstract/16/9/5210"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; Ogryzko,VV; 16(9):5210-5218 (1996)</A>].
Stress-induced senescence due to Ras protein requires signalling from the p38 (stress-activated)
form of Mitogen-Activated Protein Kinase (MAPK) and cannot be prevented by hTERT-mediated
telomerase elongation. TGF−ß inhibits telomerase and, like Ras protein, mediates
senescence by p38 MAPK activation. Cellular senscence due to DNA damage can be triggered
by p38 MAPK signalling and does not require ATM
protein [<A HREF="http://www.jbc.org/cgi/content/full/279/3/2030"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Naka,K; 279(3):2030-2037 (2004)</A>].
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>TGF−ß and insulin/IGF−1 pathways leading to dauer</B></CAPTION>
<TR><TD WIDTH="400">
<img src="TGF_path.jpg" width="400" height="300" alt="Cell Divisons and Cell Senescence">
</TR></TD>
</TABLE>
<p>Homeostasis and remodeling of the extracellular matrix is mediated in large part through
an interplay of Matrix MetalloProteinases (<b>MMP</b>s, collagenase) and Tissue Inhibitors
of MetalloProteinases (<b>TIMP</b>s). Senescence of fibroblasts is accompanied by a shift
from matrix synthesizing to matrix degredation associated with increased MMP production and
decline of tissue function. TGF−ß can induce either
apoptosis [<A HREF="http://endo.endojournals.org/cgi/content/full/142/6/2419"
TARGET="_blank">ENDOCRINOLOGY; Bruckheimer,EM; 142(6):2419-2426 (2001)</A>]
or senescence [<A HREF="http://erc.endocrinology-journals.org/cgi/content/full/13/2/379"
TARGET="_blank">ENDOCRINE-RELATED CANCER; Fleisch,MC; 13(2):379-400 (2006)</A>]. Peculiarly,
TGF−ß induces TIMP and represses
MMP [<A HREF="http://www.jbc.org/cgi/content/full/278/12/10304"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Hall,M; 278(12):10304-10312 (2003)</A>].
Also peculiar is the fact that MMP production seems to be mediated by the same forkhead
family of transcription factors that are credited with increased longevity in
<B><I>C. elegans</I></B> nematode worms due to disruption of
insulin/<a href="../nutrceut/GH_IGF1.html" TARGET="_blank">IGF1−1</a>-like
signalling [<A HREF="http://www.jbc.org/cgi/content/full/277/10/7857"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Mawal-Dewan; 277(10):7857-7864 (2002)</A>]
and that mutations in the TGF−ß pathway can induce <B><I>C. elegans</I></B>
dauer formation, but (unlike mutations in the insulin/IGF−1 pathway) do not extend
adult nematode lifespan [<A HREF="http://www.biomedcentral.com/1471-213X/4/11"
TARGET="_blank">BMC DEVELOPMENTAL BIOLOGY; Liu,T; 4:11 (2004)</A>].
(See <a href="#longevity" target="_blank">LONGEVITY GENES (FLIES & WORMS)</a> for
more about <B><I>C. elegans</I></B> dauer formation and lifespan extension
associated with insulin/IGF−1 signalling.)
<p>Both p53 and pRB participate in apoptosis as well as senescence. Whereas p53 induces
apoptosis in response to DNA damage, loss of pRB leads to apoptosis and deregulated
cell proliferation [CURRENT OPINION IN GENETICS & DEVELOPMENT; Hickman,ES;
12(1):60-66 (2002)]. The p53 protein not only induces apoptosis by increasing gene
expression of Bax, Bak and a number of other proteins [BIOCHEMICAL AND
BIOPHYSICAL RESEARCH COMMUNICATIONS; Michalak,E; 331(3):786-798 (2005)], but p53 also
directly activates Bax protein in the cytoplasm [SCIENCE; Chipuk,JE; 303:1010-1014
(2004)].
<P>What is the relationship between cellular senescence, apoptosis, cancer and aging?
Apoptosis in development is the reason humans do not have webbed hands. In the developing
nervous system cell proliferation accompanies apoptosis with "survival of the
fittest" synaptic connections. The great majority of T−lymphocytes produced are
eliminated by apoptosis, an important defense against auto-immune disease. T−cells
express a <B>Fas</B> (CD95) receptor which mediates an apoptotic signal that bypasses
nuclear transcription and directly activates proteases, thus terminating the immune response.
Fas receptor expression on T−cells increases with aging, enhancing the susceptibility
of T−cells to apoptosis [CELL AND TISSUE RESEARCH; Higami,Y; 301(1):125-132
(2000)].
<p>A youthful, healty organism has efficient cell-cycle control and can thereby resist
undesirable apoptosis while efficiently using apoptosis when needed. Cells having DNA defects
or mitochondria producing excessive free radicals can be eliminated by apoptosis and
macrophages without causing inflammation. Aged cells with less effective cell-cycle control
will less readily apoptose when defective, but will more often dysfunctionally apoptose. High
levels of apoptosis in aged tissues result in tissue degeneration. Accumulated free radical,
glycation and other forms of cellular damage lead increasingly to dysfuncional cell-cycle
control with age. Some of those immersed in genetic paradigms of aging assert that
CRAN (<A HREF="../calories/calories.html" TARGET="_blank">Caloric Restriction with
Adequate Nutrition</A>) "up-regulates" apoptosis in cancer cells while
"down-regulating" apoptosis in normal cells. A more reasonable explanation
might be that by reducing oxidative stress & glycation, CRAN maintains youthful
cell-cycle control.
<p>Apoptosis may be protective in some tissues,
whereas cellular senescence may be more protective against cancer in other tissues.
Reduction of nitric oxide synthesis with aging reduces the nitric oxide inhibition of
endothelial cells apoptosis — leading to a worsening of atherosclerotic disease.
Endothelial cells have a high rate of telomere loss and senescent endothelial cells
contribute to atherosclerosis by the release of pro-inflammatory
cytokines [<A HREF="http://circ.ahajournals.org/cgi/content/full/105/13/1541"
TARGET="_blank">CIRCULATION; Minamino,T; 105(13):1541-1544 (2002)</A>].
<P>The "longevity gene" SIRT1 gene
silencing protein increases cell cycle arrest by FOXO transcription factor while
inhibiting FOXO's induction of apoptosis [SCIENCE; Brunet,A; 303:2011-2015 (2004)].
The <B>p53 protein</B> arrests cell growth
(<A HREF="../health/cancer.html#cellcycle" TARGET="_blank">cell cycle arrest</A>)
& triggers cell suicide (apoptosis) — typically as a response to DNA damage.
Normally p53 protein induction of cellular senescence (halted growth cycle) is regarded
as a defense against cancer, but SIRT1 inhibition of p53-mediated apoptosis and
cell senescence is presumed to be life-extending by allowing for cell repair.
<P>Cellular senescence has been called an "antagonistic pleiotropic trait" that
benefits young organisms at the expense of harm to older organisms. An exaggerated example
of this may be <B>p53<SUP>+/m</SUP></B> mutant mice, which show enhanced p53 protein
activity. Although the mutant mice show an accelerated aging phenotype and only live
80% as long as normal mice, cancer is exceedingly rare in these
mutants [NATURE; Tyner,SD; 415:45-53 (2002)]. The mice support the views that cellular
senescence/apoptosis is a defense against cancer and that cellular senescence/apoptosis
can lead to senescence (aging)
of the organism as a whole. Cellular senescence may also be antagonistically pleiotropic
due to the secretions of senescent cells, which have been shown to promote cancer growth in
surrounding tissues [<A HREF="http://www.pnas.org/cgi/content/full/98/21/12072"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Krtolica,A;
98(21):12072-12077 (2001)</A>].
<P>Werner's Syndrome (reputedly the segmental progeria most resembling accelerated aging)
is often characterized as a disease of accelerated telomerase functioning and cellular
senescence. In contrast to normal human fibroblasts which senesce after about
50 population doublings, Werner's patients' fibroblasts usually senesce after about
20 doublings — with longer than normal telomeres. The WRN protein, which is defective
in Werner's patients is a <B>helicase</B> (enzyme that unwinds double helical regions in DNA
and RNA) and an <B>exonuclease</B> (enzyme that catalyzes hydrolytic removal of nucleotides
from the end of DNA and RNA).
<P>Werner's patient fibroblasts are resistant to apoptosis. The high proportion of sarcomas
in those patients may be due to the promotion of transformation of the non-senescent
cells by the proteases & cytokines created by the many senescent cells. Werner's
Syndrome is not simply a model system of the effect of a high proportion of senescent cells
because defective DNA repair plays such a prominent role in the disease.
<P>Transgenic mice that have defective repair of mitochondrial DNA will have reduced lifespan,
increased apoptosis and display an "accelerated aging"
phenotype [<A HREF="http://www.sciencemag.org/cgi/content/full/309/5733/481"
TARGET="_blank">SCIENCE; Kujoth,GC; 309(5733):481-484 (2005)</A>]. The mice show no sign of
oxidative stress or increased free radical production.
<P>In general, apoptosis can be described as being <B>signal-induced</B> or
<B>damage-induced</B>. <B>Signal-induced apoptosis</B> is essential for the precision
elimination of undesirable cells following proliferation of many cell types, including
clonal expansion of T−cells. Well-controlled apoptosis is a feature of an efficient
immune system. <B>Damage-induced apoptosis</B> is a major factor in neurodegeneration,
although the process undoubtedly becomes increasingly necrotic. The same may be true for
macrophages that die in atherosclerotic plaques. If the immune system induces apoptosis
in cancer cells, it could involve both forms of apoptosis. There is a decrease in both
kinds of apoptosis with age, as cellular signalling and regulation (including apoptotic
regulation) becomes less efficient. A tissue deprived of many cells because of a high level
of apoptosis may display the "aged phenotype" as much as a tissue composed
largely of senescent cells that are too defective to undergo apoptosis.
<P>A <A HREF="#biomarkers" TARGET="_blank">biomarker</A> of cell senescence would facilitate
the identification and study of senescent cells, as well as the targeting for destruction
of such cells. The most promising candidate biomarker, <B>ß-galactosidase</B>, is
elevated in replicative senescence and can quantitatively estimate replicative age
<B><I>in vitro</I></B>. But cellular ß-galactosidase also is present in immortal cells
and can be induced by subjecting cells to hydrogen peroxide [EXPERIMENTAL CELL
RESEARCH; Severino,J; 257:162-171 (2000)].
<P>It has been suggested that reprogramming cells to apoptose rather than senesce may
be a means to reduce cancer and eliminate one cause of aging.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="progeria">XIV. "ACCELERATED AGING" DISEASES
(SEGMENTAL PROGERIA) </a></H3>
<p>"Accelerated aging" is distinct from accelerated mortality
because "accelerated aging" diseases exhibit an elderly
phenotype and increased disposition to aging-associated diseases such
as <a href="../health/cancer.html" target="_blank">cancer</a>
and <A HREF="./Alzheimer.html" TARGET="_blank">Alzheimer's Disease</A>.
Too often, however, "accelerated aging" is equated with
increased disposition to aging-associated diseases in the absence of an
elderly phenotype). High blood pressure and AIDS accelerate mortality
without exhibiting an elderly phenotype. Without objective
<a href="#biomarkers" target="_blank">biomarkers of aging</a> the "elderly
phenotype" is open to dispute.
<P> No disease condition displays all symptoms of accelerated aging.
Diseases that resemble certain aspects of accelerated aging are
known as <B>segmental progerias</B>, because of the "segments"
of aging in each disease condition. If aging is due to a variety of cellular
and molecular damages, segmental progerias may represent subsets of those
damages.
<p>Segmental progerias primarily are diseases of defective
DNA-repair, <a href="#glycation" target="_blank">although diabetics also
show many features of accelerated aging</a>. Defects in
Base Excision Repair (BER), however, are generally too lethal to manifest as accelerated
aging [SCIENCE; Hasty,P; 299:1355-1359 (2003)].
(<a href="http://www.rndsystems.com/mini_review_detail_objectname_MR04_GenomicInstability.aspx"
target="_blank">Genomic instability syndromes</a> are not necessarily progerias.)
<p>It has been proposed that segmental progerias result from decreased cytotoxic DNA
damage repair or from an exaggerated response to DNA damage signals — whereas
cancers result from decreased mutagenic DNA damage repair or from an impaired
response to DNA damage signals — with excision repair mainly effective against
cancer and transcription-coupled (or interstrand cross-link) repair mainly facilitating
longevity [CURRENT OPINION IN CELL BIOLOGY; Mitchell,JR; 15(2):232-240 (2003)].
Progeroid syndromes have been associated with NER and DSB repair, but not with BER
or MMR [JOURNAL OF INTERNAL MEDICINE; Lombard,DB; 263(2):128-141 (2008)]. In both
human patients and mouse models only some DNA repair defects show accelerated aging,
namely the TCR subtype of NER and defects to NHEJ genes. The GGR subtype of NER
mainly results in increased carcinogenesis and "photo-aging", although
there is neurodegeneration. BER defects are generally lethal [SCIENCE; Hasty,P;
299:1355-1359 (2003)], but SIRT6 (which facilitates BER by an unknown mechanism)
knockout mice do show an accelerated aging phenotype (including loss of subcutaneous
fat and decreased bone density) during the few weeks in which they are able to
survive [Mostoslavsky, 2006].
<P><B>Werner's syndrome</B> (<b>WS</b>) is associated with early onset of very many age-related
diseases and most closely represents accelerated aging of any of the segmental
progerias. About two-thirds of WS victims are Japanese (attributed to inbreeding).
WS is due to a defect or deletion of a single gene
(<B>WRN</B>), resulting in defects of both telomeres and DNA
repair [<A HREF="http://mcb.asm.org/cgi/content/full/24/19/8437"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; Du,X; 24(19):8437-8446 (2004)</A>].
The <B>WRN gene</B> is
a member of the <B>helicase</B> family that causes DNA to unwind, which is a requirement for
most forms of DNA repair. Defective WRN protein results in a reduction of p53-mediated
apoptosis. There is an accelerated rate of somatic mutations, particularly
deletions [<A HREF="http://www.pnas.org/content/86/15/5893"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Fukuchi,K;
86(15):5893-5897 (1989)</A>], although defects are also probable in BER and
NHEJ [MECHANISMS OF AGEING AND DEVELOPMENT; Kusumoto,R; 128(1):50-57 (2007)].
Defective homologous recombination is believed to
be the primary reason for the chromosomal abnormalities of WS
victims [<A HREF="http://genesdev.cshlp.org/content/15/8/933"
TARGET="_blank">GENES & DEVELOPMENT; Prince,PR; 15(8):933-938 (2001)</A>
and <A HREF="http://mcb.asm.org/cgi/content/full/22/20/6971"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; Saintigny,Y; 22(20):6971-6978
(2002)</A>]. Defective recombination leads to genomic instability and thus
greatly increased risk of cancer, particularly sarcomas (the relative incidence of mesenchymal
cell cancer compared to epithelial cell cancer is ten times
normal) [<A HREF="http://cebp.aacrjournals.org/cgi/reprint/5/4/239"
TARGET="_blank">CANCER EPIDEMIOLOGY, BIOMARKERS & PREVENTION; Goto,M;
5(4):239-246 (1996)</A>]. WRN has been described as a tumor-suppressor
gene because epigenetic silencing of WRN increases chromosomal
instability and because tumor-types match those of other tumor-suppressor
gene defects [<A HREF="http://www.pnas.org/cgi/content/full/103/23/8822"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Agrelo,R; 103(23):8822-8827 (2006)</A>]. But WRN also acts as a tumor suppressor
by its facilitation of p53-mediated
apoptosis [<A HREF="http://genesdev.cshlp.org/content/13/11/1355"
TARGET="_blank">GENES & DEVELOPMENT; Spillare,EA; 13(11):1355-1360 (1999)</A>].
Unlike carcinomas, mesenchymal
tumors primarily maintain telomeres by the ALT
mechanism [<A HREF="http://jcs.biologists.org/cgi/content/full/120/5/713"
TARGET="_blank">JOURNAL OF CELL SCIENCE; Multani,AS; 120(Pt 5):713-721
(2007)</A>]. Although mesenchymal malignancies predominate for both mice
& WS victims, WRN knockout mice show no sign of accelerated
aging despite reduced cellular proliferation
capacity [<A HREF="http://www.pnas.org/cgi/content/full/95/22/13097"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Lebel,N; 95(22):13097 (1998)</A>]. Whereas normal human
fibroblasts experience replicative senescence after about 60 divisions, the fibroblasts
of WS patients senesce after about
20 divisions [<A HREF="http://www.pnas.org/cgi/content/abstract/90/24/12030"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Faragher,RGA;
90(24):12030-12034 (1993)</A>]. The accelerated senescence of fibroblasts from WS
patients is associated with an accelerated accumulation of double-strand
breaks [<A HREF="http://www.jstage.jst.go.jp/article/jrr/48/3/48_219/_article"
TARGET="_blank">JOURNAL OF RADIATION RESEARCH; Ariyoshi,K; 48(3):219-231 (2007)</A>].
Telomeres are of
normal length initially, but shorten at an abnormally high rate, resulting in many so-called
senescent cells (creating a model system for the study of the senescent cell phenotype).
Telomere repair is reduced, as is MisMatch Repair (MMR), TCR Base Excision Repair (BER)
and double-strand break repair of DNA.
Transcription of mRNA by RNA polymerase II from DNA is roughly half
as efficient in WS cells compared to normal
cells [<A HREF="http://www.molbiolcell.org/cgi/content/full/10/8/2655"
TARGET="_blank">MOLECULAR BIOLOGY OF THE CELL; Balajee,AS; 10(8):2655-2668
(1999)</A>]. The disease first becomes evident in the
late teens or early 20s, and typically results in death by age 50 by cardiovascular
disease. Osteoporosis, premature hair graying, alopecia, high blood pressure, stroke,
cataracts, severe atherosclerosis, and type 2 diabetes are extremely
common [MECHANISMS OF AGING & DEVELOPMENT; Goto,M; 98(3):239-254 (1997)].
Many of these effects may be due to increased levels of the inflammatory cytokines
produced by aging and senescent cells [EXPERIMENTAL GERONTOLOGY; Kumar,S;
28(6):505-513 (1993) and REJUVENATION RESEARCH; Davis,T; 9(3):402-407 (2006)].
Conversely, proinflammatory cytokines have been shown to induce cellular
senescence [FREE RADICAL RESEARCH; Sasaki,M; 42(7):625-632 (2008)].
Abnormally high levels of collagenase from senescent fibroblasts leads to loss of skin
elasticity and to skin wrinkling. Experimentally produced cellular senescence in
rat arteries results in an atherosclerotic phenotype matching that seen in WS and
normal aging [<A HREF="http://circ.ahajournals.org/cgi/content/full/108/18/2264"
TARGET="_blank">CIRCULATION; Minamino,T; 108(18):2264-2269 (2003)</A>], which
supports the general contention that cell senescence contributes significantly
to the normal aging phenotype. At a much faster rate than is often seen in normal
aging, WS victims accumulate visceral fat, develop high levels of the plasma
<a href="http://en.wikipedia.org/wiki/Cytokine" target="_blank">cytokine</a>
<a href="#inflame" target="_blank">TNF−α</a>, develop insulin resistance
and show a <a href="../health/MacroNut.html#syndrome" target="_blank">metabolic
syndrome</a> profile, but without being
obese [<A HREF="http://care.diabetesjournals.org/cgi/content/full/27/10/2562"
TARGET="_blank">DIABETES CARE; Yokote,K; 27(10):2562-2563 (2004)</A>].
The carbonyl content of proteins in
WS victims increases exponentially with age at a much higher rate than normal.
Microarray profiling of 6,912 human fibroblast genes showed 91% of the
genes were common to WS and aging cells, 6% were unique to normal aging
and 3% were unique to
WS [<A HREF="http://www.pnas.org/cgi/content/full/100/21/12259"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Kyng,KJ; 100(21):12259-12264 (2003)</A>].
But WS victims show no increased tendency for neurodegeneration, prostate
problems or Alzheimer's Disease — and the immune system remains normal. The
progeroid symptoms of WS have been attributed to both increased cellular
senescence [SCIENCE; Kipling,D; 305:1426-1431 (2004)] and increased
apoptosis [<A HREF="http://www.molbiolcell.org/cgi/content/full/17/4/1583"
TARGET="_blank">MOLECULAR BIOLOGY OF THE CELL; Pichierri,P; 12(8):2412-2421 (2001)</A>].
<P> In <B>Hutchinson-Gilford Progeria Syndrome</B> (<b>HGPS</b>, "childhood progeria",
in contrast to the "adult progeria" of Werner's syndrome)
a child is born with abnormally short telomeres. Childhood progeria occurs
once per 4−8 million births. Victims are characterized by short stature, early
hair loss, cardiovascular problems (stroke and coronary dysfunction are common)
and an elderly facial phenotype, but normal cognition and immune function, and
no disposition to cancer [AMERICAN JOURNAL OF MEDICAL GENETICS (PART A);
Hennekam,RCM; 140(23):2603-2624 (2006)].
The disease is caused by a point mutation in the gene for
<B>lamin A</B>, a filament protein in the nuclear matrix and nuclear lamina
that is required for DNA replication and nuclear organization. The point mutation
results in a <B>prelamin A</B> protein called <b>progerin</b> that cannot be
converted to lamin A because it is missing 50 amino acids. Progerin
retains a hydrophobic
<a href="http://en.wikipedia.org/wiki/Farnesol" target="_blank">farnesyl</a> group
(normally cleaved by the protease ZMPSTE24) which causes it to be highly membrane-associated.
The intranuclear scaffold
formed by lamins may facilitate transcription, replication and DNA repair [NATURE
MEDICINE; Liu,B; 11(7):780-785 (2005)]. Disruption of nuclear lamin organization
inhibits mRNA transcription (RNA polymerase II activity) in mammalian
cells [<A HREF="http://jcb.rupress.org/cgi/content/full/156/4/603"
TARGET="_blank">THE JOURNAL OF CELL BIOLOGY; Spann,TP; 156(4):603-608 (2002)</A>].
DSBs accumulate in HGPS and ZMPSTE24-deficient
cells, where DSB-repair is apparently blocked by accumulation of mis-localized XPA
protein at the damage
site [<A HREF="http://www.fasebj.org/cgi/content/full/22/2/603"
TARGET="_blank">THE FASEB JOURNAL; Liu,Y; 22(2):603-611 (2008)</A>].
Cells with the lamin A mutation show an
impaired ability to form foci for the recruitment of DNA repair
proteins during DNA replication, resulting in defective homologous
recombination [NATURE MEDICINE; Liu,B; 11(7):780-785 (2005) and
<A HREF="http://jcs.biologists.org/cgi/content/full/119/13/2704"
TARGET="_blank">JOURNAL OF CELL SCIENCE; Manju,K; 119(Pt 13):2704-2714 (2006)</A>
and DNA REPAIR; Paulson;RD; 6(7):953-966 (2007)].
At age 5 the telomeres of a
Hutchinson-Gilford syndrome child are about as long as those of a very elderly person.
HGPS patient cells show loss of epigenetic
control [<A HREF="http://www.pnas.org/cgi/content/full/103/23/8703"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Shumaker,DK;
103(23):8703-8708 (2006)</A>]. A study which compared HGPS patient cells with the skin
cells from young & elderly human subjects found similar defects in the HGPS & elderly
cells, including down-regulation of certain nuclear proteins, increased DNA damage
and demethylation of H3 histone leading to reduced heterochromatin, suggesting
that lamin A defects contribute to normal aging [SCIENCE; Scaffidi,P;
312:1059-1063 (2006)]. Nuclear levels of phosphorylated <b>H2AX</b> — which
recruits DNA repair proteins to sites of DNA damage [SCIENCE; Celeste,A; 296:992-997
(2005)] — is more than three times higher in fibroblasts from old
(81 to 96 years) as compared to young (3 to 11 years) normal humans [SCIENCE;
Scaffidi,P; 312:1059-1063 (2006)], comparable to what is seen in HGPS cells [NATURE
MEDICINE; Liu,B; 11(7):780-785 (2005)].
Most often these children die of myocardial infarction or
stroke (average age of death is 13). The premature atherosclerosis is without the
usual causes association with high blood pressure or high blood cholesterol. Progestin
preferentially accumulates in the nuclei of vascular smooth muscle and endothelial
cells causing the cells to senesce or become
apoptotic [<A HREF="http://www.pnas.org/cgi/content/full/103/7/2154"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
McClintock,D; 103(7):2154-2159 (2006)</A>]. Carbonyl content of protein rises
more rapidly with age than in any of the other segmental progerias.
These children do not have the high rates of presbyopia, cataracts, osteoporosis or
<A HREF="../lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's Disease</A>
often seen in the elderly. Like WS, HGPS is primarily a disease of proliferative
tissues characterized by high rates of cellular senescence and
apoptosis [EXPERIMENTAL GERONTOLOGY; Bridger,JM; 39(5):717-724 (2004)].
<P><B>Bloom's syndrome</B>, like Werner's syndrome, is due to a defective
helicase-type protein, in this case <B>BLM</B> — leading to chromosome
aberrations [<A HREF="http://nar.oxfordjournals.org/cgi/content/full/35/22/7527"
TARGET="_blank">NUCLEIC ACIDS RESEARCH; Brosh,RM; 35(22):7527-7544 (2007)</A>].
The disease is most common in Ashkenazi Jews (descendents of Eastern European
Jews) due to intensive inbreeding. Victims are small at birth and rarely
grow to be taller than 5 feet. Intelligence is usually normal. Photosensitivity
causes the face to be red. Approximately 10% of victims have type 2 diabetes.
Immunodeficiency leads to recurrent severe infections of the respiratory tract
and ear. Women have reduced fertility and men are usually completely infertile.
Death is most often due to cancer. If they survive death from leukemia at an average
age of 22, Bloom's victims usually die of solid tumors at an average age of 35.
BLM protein is preferentially expressed in proliferative tissues containing
high levels of telomerase. BLM protein deficiency renders cells highly vulnerable to
p53-induced apoptosis, which is
suggested to contribute to growth retardation. During the S-phase of the cell
cycle BLM protein localizes in the nucleolus where it apparently assists in the
resolution of stalled replication
forks [<A HREF="http://www.pnas.org/cgi/content/full/97/10/5214"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Yankiwski,V;
97(10):5214-5219 (2000)</A>]. The BLM protein is normally found
mainly in the PML bodies of the nucleus, but when NHEJ
is required to repair DSBs, BLM protein causes rapid
recruitment of BRCA1 protein to the site of
damage [<A HREF="http://www.jcb.org/cgi/content/full/162/7/1197"
TARGET="_blank">JOURNAL OF CELL BIOLOGY; Davalos,AR; 162(7):1197-1209 (2003)</A>].
The high rate of apoptosis in Bloom's Syndrome victims would be predictive
of an accelerated aging phenotype with reduced cancer, but high proliferation
& decreased genome stability selects for p53 mutations which reduce
apoptosis & foster cancer [<A HREF="http://www.jcb.org/cgi/content/full/162/7/1197"
TARGET="_blank">JOURNAL OF CELL BIOLOGY; Davalos,AR; 162(7):1197-1209 (2003)</A>].
BLM protein highly co-localizes with telomeres in cells maintaining telomere
length by the ALT mechanism, but not in normal or telomerase-positive
cells [<A HREF="http://hmg.oxfordjournals.org/cgi/content/full/11/25/3135"
TARGET="_blank">HUMAN MOLECULAR GENETICS; Stavropoulos,DJ; 11(25):3135-3144
(2002)</A>]. Chromosomal breaks and a greatly elevated rate of sister chromatid
exchanges are characteristic features of Bloom's
syndrome [<A HREF="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=868871"
TARGET="_blank">AMERICAN JOURNAL OF HUMAN GENETICS; German,J; 29(3):248-255 (1977)</A>].
BLM protein prevents excessive homologous recombination [NATURE;
Wu,L; 426:870-874 (2003)], particularly where
<a href="http://en.wikipedia.org/wiki/D-loop" target="_blank">D−loops</a>
are formed [<A HREF="http://nar.oxfordjournals.org/cgi/content/full/34/8/2269"
TARGET="_blank">NUCLEIC ACIDS RESEARCH; Bachrati,CZ; 34(8):2269-2279(2006)</A>].
BLM protein also complexes with the <B>Rad51</B> protein in homologous recombination
repair of double-strand DNA
breaks [<A HREF="http://www.jbc.org/cgi/content/full/278/48/48357"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Braybrooke,JP;
278(48):48357-48366 (2003)</A>] and inhibits the exonuclease activity of WRN
protein [<A HREF="http://www.jbc.org/cgi/content/full/277/24/22035"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; von Kobbe,C; 277(24):22035-22044
(2002)</A>].
<P> <B>Down's syndrome</B> is caused by an extra copy of chromosome 21, the
shortest human chromosome (50-million base-pairs). One birth in 700 is a
Down's baby — most frequently seen in the babies of women giving birth
in their 30s or 40s. The disease accounts for one-third of all cases
of mental retardation in industrialized countries. Down's syndrome victims
have short stature, hearing deficits and features of accelerated aging, which
include hair graying & hair loss and increased tissue
lipofuscin levels. One third of Down's victims have hypothyroidism.
Although the overall cancer incidence may be lower, the incidence of
leukemia is 10 to 20 times higher than normal. Down's syndrome
victims are very vulnerable to infection, due to the rapid shortening
of the telomeres of their leukocytes (white blood cells). Almost all
Down's syndrome victims have
<A HREF="../lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's Disease</A>
by age 50, probably
because chromosome 21 carries the amyloid gene. Chromosome 21
also carries Cu/Zn SuperOxide Dismutase gene, resulting in increased
production of hydrogen peroxide (H<SUB>2</SUB>O<SUB>2</SUB>) which
(without catalase or glutathione peroxidase) can lead to more hydroxyl
radicals. Down's syndrome victims show a 50% increase in cytoplasmic
SOD. Cultured cells transfected with an increased gene dosage of cytoplasmic
SOD show features of cellular senescence mediated by hydrogen
peroxide [<A HREF="http://hmg.oxfordjournals.org/cgi/content/full/5/2/283"
TARGET="_blank">HUMAN MOLECULAR GENETICS; de Haan,JB; 5(2):283-292 (1996)</A>].
The incidence of diabetes is 5−10 times greater for Down's
syndrome victims than for age-matched controls. Nonetheless, Down's syndrome
victims show no accelerated vulnerability for breast & prostate cancer,
high blood pressure, or osteoporosis.
<p><B><a href="http://en.wikipedia.org/wiki/Xeroderma_pigmentosum" target="_blank">Xeroderma
pigmentosum</a></B> (<B>XP</B>) patients show tissue-specific signs of premature aging,
mainly of the skin & eyes ("photoaging"), have a high
incidence of skin cancer (more than a thousand-fold over normal) and have neurological
problems. Although XP victims rarely reach the age of 30, for the most part they
do not display an "accelerated aging" phenotype. XP
is due to compromised Nuclear Excision Repair (NER)
due to defects in any one of seven genes/proteins designated <b>XPA</b> to <b>XPG</b>.
XPB and XPD are <a href="http://en.wikipedia.org/wiki/Helicase" target="_blank">helicases</a>
which are part of the NER
<a href="http://en.wikipedia.org/wiki/Transcription_factor" target="_blank">transcription
factor</a> <b>TFIIH</b>. XPC and XPE are proteins that recognize DNA damage.
Patients with defects in XPC (which functions exclusively in GG-NER) do not
suffer the severe neurological disease that can be seen in patients with XPA
defects [DNA REPAIR; Niederhofer,LJ; 7(7):1180-1189 (2008)]. XPF and
XPG are <a href="http://en.wikipedia.org/wiki/Endonuclease" target="_blank">endonucleases</a>.
The XPF-ERCC1 endonuclease functions in both Global Genome Nuclear Excision
Repair (<b>GG−NER</b>) and repair of crosslinks between DNA strands. XP can even
be caused by mild mutations of the XPF subunit of the XPF−ERCC1 endonuclease — which is
used to replace pyrimidine dimers. DNA repair capability is particularly
important in the brain because neurons are not replaced, but have high
metabolic demands which subject them to high oxidative stress. For this reason, reduced
repair of oxidative DNA damage is a reasonable explanation for the neurodegeneration
seen in XP patients [<A HREF="http://www.pnas.org/content/94/17/9463"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Reardon,JT; 94(17):9463-9468 (1997)</A>]. Cells from XP patients with neurodegeneration
show extremely poor NER of free-radical induced bulky DNA
lesions [<A HREF="http://www.jbc.org/cgi/content/full/275/29/22355"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Brooks,PJ; 275(29):22355-22362 (2000)</A>].
<p>Transgenic mice which are null for both XPF & ERCC1 proteins are defective
in both NER and DNA interstrand crosslink repair, which leads to <b>XFE progeria</b>.
Defective crosslink repair leads to DSBs in these
mice [<A HREF="http://mcb.asm.org/cgi/content/full/24/13/5776"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; Niedernhofer,LJ; 24(13):5776-5787
2004)</A>]. In XFE
progeria there is more cell senescence and more apoptosis, but less mutation and telomere
loss [NATURE; Niedernhofer,LJ; 444:1038-1043 (2006)]. These mice show accelerated
aging, but suppressed carcinogenesis [NATURE; Niedernhofer,LJ; 444:1038-1043 (2006)].
Interstrand crosslink repair necessitates NER followed by HR [THE LANCET
ONCOLOGY; McHugh,PJ; 2(8):483-490 (2001)]. Complicating matters is reduced serum
<a href="../nutrceut/GH_IGF1.html" target="_blank">IGF1</a>, which is believed to
be an adaptive response to DNA damage [NATURE; Niedernhofer,LJ;
444:1038-1043 (2006)].
<P><B>Cockayne syndrome</B> is due to a defective protein which is required
for the Transcription-Coupled Repair (TCR) subtype of Nucleotide Excision
Repair (NER) of DNA. Although newborns appear normal there is early
dwarfism ("cachectic dwarfism"), mental retardation, cataracts,
deafness, photosensitivity, osteoporosis, dental caries, sparse hair and
a senile-like appearance (including a pinched, narrow face and a beaked nose,
due to reduced subcutaneous fat) [PEDIATRIC NEUROLOGY; Ozdirim,E;
15(4):312-316 (1996)]. Microcephaly results from cell loss during
brain development due to various kinds of DNA damage. There may be premature
atherosclerosis, high lipofuscin accumulation in neurons and
<A HREF="../lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's</A>
neurofibrillary tangles. The most common causes of death are pneumonia (probably
due to the general atrophy) and
neurodegeneration [<A HREF="http://hmg.oxfordjournals.org/cgi/content/full/15/suppl_2/R151"
TARGET="_blank">HUMAN MOLECULAR GENETICS; Navarro,CL; 15(2):R151-R161 (2006)</A>].
Neurodegeneration may be indicative of the significance of failed TCR (or BER) in
postmitotic tissues leading to apoptosis, and the high rate of repair required
by brain tissue due to high oxidative metabolism [MECHANISMS OF AGEING AND
DEVELOPMENT; Stevnsner,T; 129(7-8):441-448 (2008)].
About 25% of cases have defective CSA protein and die at an average age of
12.5, whereas the rest have defective CSB protein and die at an average age of 6.5.
Oxidative stress lesions to DNA accumulate at a rapid rate in victims with CSB defects,
indicative of deficient Base Excision Repair
(BER) [<A HREF="http://www.fasebj.org/cgi/content/full/17/6/668"
TARGET="_blank">THE FASEB JOURNAL; Tuo,J; 17(6):668-674 (2003)</A>
and <A HREF="http://mcb.asm.org/cgi/content/full/24/18/7941"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; de Waard,H;
24(18):7941-7948 (2004)</A>]. Despite showing many of the same symptoms as
XP victims, Cockayne syndrome victims have no predisposition
to cancer because of inhibited transcription binding leading to a
high rate of apoptosis (to which is attributed
features of premature aging). Cancer cells are heavily dependent upon
transcription, so it is reasonable that defective TCR would strongly inhibit
proliferation, but favor high levels of senescence or apoptosis ("accelerated
aging" rather than
cancer) [<A HREF="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=14639525"
TARGET="_blank">THE AMERICAN JOURNAL OF HUMAN GENETICS; Licht,CL; 73(6):1217-1239 (2003)</A>].
Transgenic mice that replicate Cockayne Syndrome show suppression of
GH/<a href="../nutrceut/GH_IGF1.html" TARGET="_blank">IGF1−1</a without
the longevity benefits seen in the IGF1-deficient dwarf
mice [<A HREF="http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0050002&ct=1"
TARGET="_blank">PLoS BIOLOGY; van der Pluijm,I; 5(1):e2 (2007)</A>].
<p><b>Trichothiodystrophy</b> (<b>TTD</b>) is due to defects in the
<a href="http://en.wikipedia.org/wiki/Transcription_factor" target="_blank">transcription
factor</a> <a href="http://en.wikipedia.org/wiki/Transcription_Factor_II_H"
target="_blank"><B>TFIIH</B></a> protein required for both NER and normal
<a href="http://en.wikipedia.org/wiki/Transcription" target="_blank">transcription</a>.
Most often these defects are in the XPB (3´−>5´
<a href="http://en.wikipedia.org/wiki/Helicase" target="_blank">helicase</a>) or
XPD (5´−>3´ helicase) subunits of TFIIH. One type of mutation in XPD
leads to xeroderma pigmentosum, whereas other mutations lead to
TTD [<A HREF="http://hmg.oxfordjournals.org/cgi/content/full/11/23/2919"
TARGET="_blank">HUMAN MOLECULAR GENETICS; Botta,E; 11(23):2919-2928 (2002)</A>].
TTD patients do not show increased incidence of cancer. Whereas XP patients
experience neuronal degeneration, Cockayne Syndrome (CS) and TTD patients suffer from
failure to develop brain myelin. CS and TTD patients may suffer more from defective
normal transcription, whereas XP patients may suffer more from defective
transcription in
NER [<A HREF="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17276014"
TARGET="_blank">NEUROSCIENCE; Kraemer,KH; 145(4):1388-1396 (2007)</A>]. TTD victims
(including transgenic mice) show more accelerated aging than victims of Werner, Cockayne or
Bloom Syndrome. The aging phenotype (which includes osteoporosis, early greying, cachexia
and neurological abnormalities) is attributed to increased apoptosis as well as
impaired cell functioning [SCIENCE; de Boer,J; 296:1276-1279 (2002)].
<P>Like XP, <A HREF="http://www.biocarta.com/pathfiles/atmPathway.asp" TARGET="_blank"><b>Ataxia
Telangiectasia</b></A> (<B>AT</B>) is a hereditary disease (defective Ataxia Telangiectasia
Mutated, <B>ATM</B>, gene) that
reduces DNA repair and greatly increases the risk of cancer. Unlike XP, AT affects DSB repair
rather than NER, and mainly increases leukemia or lymphoma cancer-types.
AT victims exhibit growth retardation, gonadal atrophy, graying hair, immune deficiency,
accelerated telomere loss, genetic instability and cerebellar degeneration, particularly
of Purkinje and granule neurons. Neurodegeneration is the most prominent feature of
AT [NEUROMOLECULAR MEDICINE; Frappart,P; 8(4):495-511 (2006)] as a result of the
vulnerability of Purkinje cells to oxidative
stress [<A HREF="http://www.jneurosci.org/cgi/content/full/23/36/11453"
TARGET="_blank">THE JOURNAL OF NEUROSCIENCE; Chen,P; 23(36):11453-11460 (2003)</A>].
"Ataxia" means impaired motor coordination,
and ATM victims require a wheelchair before becoming teenagers due to loss of cells in cerebellum.
Clusters of dilated blood vessels (telangiectasia, "spider
veins") appear on the whites of eyes. ATM victims usually die in their teens [CELL;
Rass,U; 130(6):991-1004 (2007)]. Inhibition of ATM under conditions of DNA damage
reduces cell senescence and increases
apoptosis [<A HREF="http://www.jbc.org/cgi/content/full/280/20/19635"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Zhang,X; 280(20):19635-19640 (2005)</A>]
or simply reduces senescence<A HREF="http://www.molbiolcell.org/cgi/content/full/17/4/1583"
TARGET="_blank">MOLECULAR BIOLOGY OF THE CELL; Moiseeva,O; 17(4):1583-1592 (2006)</A>].
Nonetheless, cells of AT patients are resistant to apoptosis and do not undergo cell cycle
arrest when subjected to ionizing radiation, possibly due to the anti-apoptotic action of
AP−1 [<A HREF="http://www.jbc.org/cgi/content/full/278/9/6741"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Weizman,N; 278(9):6741-6747 (2003)</A>].
Tissues containing rapidly-dividing cells (such as the cells in the epithelium) show most
of the signs of aging. But the normal slow loss of cerebellar Purkinje cells is greatly
accelerated, leading to ataxia. Ca<SUP>2+</SUP>/cAMP Response Element Binding protein <B>CREB</B>
has anti-apoptotic action related to transcription of Bcl−2 and neuron growth factors.
Dysregulation of ATM-mediated phosphorylation of CREB in response to DNA damage may be a
significant factor in the neurodegeneration associated with
AT [<A HREF="http://www.pnas.org/cgi/content/full/101/6/5898"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Shi,Y;
101(6):5898-5903 (2004)</A>]. Although the primary symptom of AT is degeneration of the
cerebellum, the ATM protein is activated by DNA double-strand breaks [SCIENCE; Abraham,
RT; 308(5721):510-511 (2005)]. ATM stimulation in AT patients is more sensitive to
ionizing radiation & alkylating
agents than to ultraviolet radiation, whereas the reverse is true in XP patients.
XP patients are defective in NER, whereas AT patients are defective in cell cycle
control [<A HREF="http://www.jstage.jst.go.jp/article/jrr/48/1/48_31/_article"
TARGET="_blank">JOURNAL OF RADIATION RESEARCH; Kan'o,M; 48(1):31-38 (2007)</A>].
Additionally, absence of ATM protein increases telomerase instability &
loss of telomeres [ONCOGENE 21:611-618 (2002)] because DNA-damage response is part
of telomere protection and maintenance [NATURE; Verdun,RE; 447:924-931 (2007)].
<P>Like XP, <a href="http://en.wikipedia.org/wiki/Fanconi_anemia"
target="_blank">Fanconi Anemia</a> (<B>FA</B>) is a hereditary disease associated with
chromosome instability and greatly increased risk of cancer. Increased apoptosis of
hematopoetic cells typically leads to pancytopenia by age 7, with the surviving
cells characterized by genetic instability leading to acute myeloid leukemia (AML,
the most common cause of cancer in FA patients) [CELL;Niedernhofer,L;
123(7):1191-1198 (2005) and NATURE REVIEWS; D'Andrea,AD; 3(1):23-34 (2003). Median
age of death is 16, most commonly due to bone marrow failure.
Premature aging features include progressive bone marrow failure,
premature reproductive aging, hyperinsulinaemia, hypothyroidism and growth hormone
deficiency [<A HREF="http://nar.oxfordjournals.org/cgi/content/full/35/22/7566"
TARGET="_blank">NUCLEIC ACIDS RESEARCH; Grillari,J; 35(22):7566-7576 (2007)</A>]. Other
FA symptoms are only marginally associated with an accelerated aging phenotype: hearing
impairment, skeletal abnormalities, cardiac abnormalities, and cafe-au-lait skin spots.
All cellular elements in the blood (erythrocytes, leukocytes, and platelets) are depressed.
FA symptoms can result in disruption of proteins required for repair of
interstrand DNA cross-links, inclucing BRCA2.
Replication fork arrest during the S phase of the cell cycle due to
DNA cross-links can activate FA protein complexes to excise cross-links and thereby
create DSBs that can be repaired by homologous
recombination [<A HREF="http://genesdev.cshlp.org/content/19/24/2925"
TARGET="_blank">GENES & DEVELOPMENT; Kennedy,RD; 19(24):2925-2940 (2005)</A>].
An increase in anemia prevalence is regarded as part of the normal aging
phenotype [JOURNAL OF THE AMERICAN GERIATRIC SOCIETY; Rothstein,G;
51(3 Suppl):522-526 (2003)],
and spontaneous DNA interstrand crosslink damage has been proposed to be the cause
of that anemia [<A HREF="http://www.nature.com/emboj/journal/v24/n4/full/7600542a.html"
TARGET="_blank">THE EMBO JOURNAL; Prasher,JM; 24(4):861-871 (2005)</A>].
<P>An analysis of human segmental progerias observed that the progerias with shortened
telomeres also showed grey hair, alopecia and nail atrophy — whereas those not having
shortened telomeres did not have those features. The study even hypothesized that
fingernail growth velosity may be a biomarker of aging [JOURNAL OF GERONTOLOGY;
Hofer,AC; 60(1):B10-B20 (2005)]. A similar study observed that although most segmental
progerias are associated with increased risk of cancer, Hutchinson-Gilford progeria and
Cockayne syndrome are not. The study concluded that lipid metabolism genes are more
influential on human lifespan than genome integrity genes [THE INTERNATIONAL JOURNAL
OF BIOCHEMISTRY & CELL BIOLOGY; 37(5):947-960 (2005)].
<P>The Senescence Accelerated Mouse (SAM) is a rodent model of accelerated aging which
is apparently related to free-radical damage, judging by various indices of such damage
in the rodent. Moreover, administration of the spin-trapping agent PBN at maturity
to reduce free-radical damage dramatically increases life span — providing support
for the free radical theory of aging [ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
854:239-250 (1998)]. This is in contrast to other segmental progerias which more often
support a DNA-repair-deficiency theory of aging.
<p>Mouse studies indicate that mutants for Ku80/Ku86 — proteins essential for NHEJ —
show an accelerated aging phenotype (kyphosis, alopecia, conjunctivitis, rectal prolapse,
osteopenia, skin atrophy, epiphysial closure, reduced lifespan), but a 13-fold reduction
of cancer incidence [<A HREF="http://www.pnas.org/content/96/19/10770"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Vogel,H;
96(19):10770-10775 (1999)</A> and <A HREF="http://mcb.asm.org/cgi/content/full/27/23/8205"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; Li,H; 27(23):8205-8214 (2007)</A>]. The control
mice showed osteoporosis, epiphysial closure as well as skin and follicular atrophy after
70 weeks or greater, whereas these symptoms were seen in the Ku 86 knockout mice
at 37 weeks, 22 weeks, and 37 weeks,
respectively [<A HREF="http://www.pnas.org/content/96/19/10770"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Vogel,H;
96(19):10770-10775 (1999)</A>]. The Ku 86 knockout mice exhibited earlier
onset of cancer, despite an overall reduced incidence (which may have been due to the
shortened lifespan and the increased cellular
senescence [<A HREF="http://www.pnas.org/content/96/19/10770"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Vogel,H;
96(19):10770-10775 (1999)</A>].
Mice with mutated XPD (a protein required for the TFIIH protein that causes
DNA unwinding in NER) show an accelerated aging phenotype which includes
osteoporosis, kyphosis, early graying, cachexia and reduced lifespan [SCIENCE;
de Boer,J; 296:1276-1279 (2002)]. Mice
mutant for reduced levels of <b>Brca1</b> (a protein for DSB repair) show both
increased cellular senescence and an accelerated aging phenotype (kyphosis, osteoporosis,
slow wound healing, reduced dermal thickness, muscular
atrophy) [<A HREF="http://www.genesdev.org/cgi/content/full/17/2/201"
TARGET="_blank">GENES & DEVELOPMENT; Cao,L; 17(2):201-213 (2003)</A>]. Mice with deficient
p53-related p63 protein also show increased cellular senescence associated with tissue
histology reflecting an accelerated aging
phenotype [<A HREF="http://www.genesdev.org/cgi/content/full/19/17/1986"
TARGET="_blank">GENES & DEVELOPMENT; Keyes,WM; 19(17):1986-1999 (2005)</A>]. Similarly,
mice deficient in ZMPSTE24 protease show hyperactivation of tumor suppressor protein p53,
leading to increased cell senescence without increased apoptosis — and an acclerated
aging phenotype [NATURE; Varela,I; 427:564-568 (2005)].
<p>The linkage of accelerated aging to nuclear DNA repair defects implies both a direct
linkage to cancer as well as cell dysfunction due to increased DNA damage/mutation,
or an indirect linkage due to increased cellular senescene and apoptosis —
depending on what causes the "aging phenotype". Transgenic
mice with hyperactive p53 protein show decreased cancer along with increased apoptosis
and cellular senescence associated with an aged phenotype and shortened
lifespan [NATURE; Tyner,SD; 415:45-53 (2002),
<A HREF="http://genesdev.cshlp.org/content/18/3/306"
TARGET="_blank">GENES & DEVELOPMENT; Maier, B; 18(3):306-319 2004)</A>,
and <A HREF="http://bloodjournal.hematologylibrary.org/cgi/content/full/109/4/1736"
TARGET="_blank">BLOOD; Dumble,M; 109(4):1736-1742 (2007)</A>].
Markers of aging for the first of these studies included
hair sparseness (hair growth decreases linearly with age in mice), slowing of wound
healing, reduced dermal thickness & subcutaneous adipose (both of which normally
decline with age), lordokyphosis (hunchbacked spine), muscle atrophy, and reduced
vigor [NATURE; Tyner,SD; 415:45-53 (2002)]. Conversely, transgenic mice with
mutated p66<sup>shc</sup> gene show impaired p53, reduced apoptosis in response
to stress and "decelerated aging" (lifespan extended
30% [NATURE; Migliaccio,E; 402:309-313 (1999)]. Transgenic mice with
extra p53 genes had normal basal p53 activity, normal lifespans (no signs of
accelerated aging), and enhanced resistance to DNA damage and cancer —
probably because of enhanced protection against p53
mutation [<A HREF="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=12426394"
TARGET="_blank">THE EMBO JOURNAL; Garcia,CI; 21(22):6225-6235 (2002)</A>]. Mice that
were transgenic with extra genes of both p53 and <b>Arf</b> (with normal activity
of both) had strong cancer resistance, increased levels of reduced glutathione (GSH)
antioxidant, and lifespan increase of 16% [NATURE; Matheu,A; 448:375-380 (2007)].
<p>In the liver (but not the brain), old rats show less than half the
apoptosis of young rats in response to DNA damage [NATURE MEDICINE; Suh,Y;
8(1):3-4 (2002)], indicative of an increased vulnerability to cancer. Cellular
senescence isn't simply a result of shortened telomeres, it is often
the result of unrepaired nuclear DNA damage throughout chromosomes [NATURE
CELL BIOLOGY; Sedelnikova,OA; 6(2):168-170 (2004) and MECHANISMS OF AGEING AND
DEVEOPMENT; von Zglinicki,T; 126(1):111-117 (2005)], although telomere-initiated
senescence is probably also a DNA damage response [NATURE; d'Adda di
Fagagna,F; 426:194-198 (2003)]. Although estimates of the number of senescent
cells vary from between less than 1% to over 15%, such cells are prominent
in osteoarthritis and atherosclerosis — and, where not prominent, contribute
to cellular dysfunction and carcinogenesis of adjacent cells by secretion of
cytokines, growth factors and other damaging
agents [NATURE REVIEWS; Campisis,J; 8(9):729-740 (2007)
and <A HREF="http://www.jbc.org/cgi/content/full/281/40/29568"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Coppe,J;
281(40):29568-29574 (2006)</A>]. Foci of DNA damage as markers of
senescent cells provide the highest estimates (15%) of cellular
senescence in aged animals [SCIENCE; Herbig,U; 311:1257 (2006)].
<P>Accelerated aging diseases can be useful models for learning about the mechanisms of aging if
they truly represent accelerated aging. When the question of the essence of aging remains undetermined,
validating biomarkers or a model of accelerated aging leads to circular reasoning. Some question that there are
<B><I>any</I></B> disease conditions which can be called "accelerated
aging" [AGING CELL; Miller,RA; 3(2):47-51 (2004)]. If it is possible to slow aging, it should
be possible to accelerate aging, but <I><B>proving</B></I> that aging has been slowed is much easier
than proving that aging has been accelerated because a long-lived organism is sufficient proof of decelerated
aging but
a short-lived organism could be the result of a specific defect. Or else the mechanisms of "accelerated
aging" could be different from those of "normal aging". But lifespan studies of nematodes
show progressive lamin disorganization in normal aging comparable to that in the accelerated
aging of HGPS progeria, and the rate of these changes can be manipulated by insulin/IGF−1-like
signaling [<A HREF="http://www.pnas.org/cgi/content/full/102/46/16690"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Haithcock,E; 102(46):16690-16695
(2005)</A>]. Similar defects in nuclear structure & function between HGPS cells and cells
in elderly humans also supports the contention
that HGPS is accelerated aging [SCIENCE; Scaffidi,P; 312:1059-1063 (2006)].
<p>Dermatologists commonly distinguish <b>photoaging</b> from <b>chronological aging</b> in the skin,
attributing most skin aging to the former rather than the latter. Singlet oxygen from ultraviolet
light increases mitochondrial DNA
deletion [<A HREF="http://www.jbc.org/cgi/content/full/274/22/15345"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Berneburg,M; 274(22):15345-15349 (1999)</A>].
Ultraviolet radiation stimulates collagen degradation while inhibiting collagen
production [<A HREF="http://ajp.amjpathol.org/cgi/content/full/165/3/741"
TARGET="_blank">AMERICAN JOURNAL OF PATHOLOGY; Quan,T; 165(3):741-751 (2004)</A>], increases oxidative
DNA damage [<A HREF="http://www.pnas.org/cgi/content/full/102/38/13538"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Kozman,S;
102(38):13538-13543 (2005)</A>] and causes stress-induced premature senescence in skin
fibroblasts [<A HREF="http://jcs.biologists.org/cgi/content/full/118/4/743"
TARGET="_blank">JOURNAL OF CELL SCIENCE; Debacq-Chainiaux,F; 118(Pt 4):743-758 (2005)</A>]. If
aging is damage to macromolecules, cells and tissues then it should not be surprising that
exogenous sources of damage could cause "accelerated aging" of specific tissues —
a "tissue-specific segmental progeria". The fact that nuclear DNA damage from exogenous agents
results in a phenotype that greatly resembles normal aging lends credence to the idea that such
damage is the basis of normal aging.
<p>Mice have been regarded as examples of "accelerated
aging" [AGING CELL; Miller,RA; 3(2):47-51 (2004)], but mice could also be
given as examples of segmental human progeria because of their high susceptibility
to cancer and their absence of atherosclerosis and Alzheimer's Disease. All human
aging could be called segmental in the sense that some people get cancer, atherosclerosis
and Alzheimer's Disease, whereas others do not. If there are multiple
forms of aging damage then there cannot be a single aging biomarker or aging phenotype.
If reduced longevity alone were a sufficient criterion for accelerated aging, then any genetic
defect which increases mortality — or even a dangerous occupation — would qualify.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="longevity">XV. LONGEVITY GENES (FLIES & WORMS)</a></H3>
<p>The nematode worm <A HREF="http://en.wikipedia.org/wiki/Caenorhabditis_elegans"
TARGET="_blank"><I>Caenorhabditis elegans</I></A> (<B><I>C. elegans</I></B>,
which is the size of a comma, and lives a few weeks) and the fruit fly
<A HREF="http://en.wikipedia.org/wiki/Drosophila_melanogaster"
TARGET="_blank"><I>Drosophila melanogaster</I></A> (<B><I>Drosophila</I></B>,
which lives a few months) are the most common invertebrate model species used
in biology. Upon reaching maturity both species are composed post-mitotic
cells, except for the germline.
<p>A study of the entire genome of <b><i>Drosophila</i></b> during
the aging process has led to the conclusion that 300 to 350 genes control
aging [CURRENT BIOLOGY; Pletcher,SD; 12(9):712-723 (2002) and CURRENT BIOLOGY;
Rose, MR; 12(9):R311-R312 (2002)]. (By extrapolation, about 500 genes would
control aging in humans.) Determining what those genes do would be a major step
toward understanding the causes of aging.
<P> <B><I>Drosophila</I></B> have the natural antioxidant enzymes SuperOxide Dismutase
(<b>SOD</b>) & CATalase (<b>CAT</b>), but
no glutathione peroxidase. <B><I>Drosophila</I></B> were created with
(1) extra Cu/Zn−SOD (cytoplasmic SOD) genes (2) extra CAT genes
and (3) extra Cu/Zn−SOD <I><B>and</B></I> extra CAT genes. Only the
flies in the third category, having both extra genes showed extended
lifespan. These transgenic flies showed 26% greater SOD activity, 73%
greater CAT activity and 34% longer
lifespan [<A HREF="http://www.jbc.org/cgi/content/full/270/26/15671"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY 270(26):15671-15674 (1995)</A>].
The authors later stated that the experiments were not conclusive because of
the genetic background of the organisms and because of artifacts of the transgenic
methods [EXPERIMENTAL GERONTOLOGY; Orr,WC; 38:227-230 (2003)]. Nonetheless,
transgenic mice expressing mitochondrial catalase by 50 times that seen in normal
mice increased maximum lifespan by about 20% [SCIENCE; Schriner,SE;
308:1909-1911 (2005)].
<P> In 1988 geneticist Tom Johnson of the University of Colorado announced the
discovery of a mutant gene in <B><I>C. elegans</I></B> that at 25ºC increased
mean life span 65% and maximum lifespan 110% [GENETICS 118:75-86
(1988)]. Johnson named the gene <B>age−1</B> in the expectation that other genes
for aging would be found. <A HREF="../calories/calories.html" TARGET="_blank">
Caloric Restriction with Adequate Nutrition</A> (CRAN)
further extends the lifespan of age−1 mutants. age−1 mutants
were shown to have elevated Cu/Zn SOD and CAT (nematodes,
unlike vertebrates, do not have glutathione peroxidase) [BIOCHEMICAL
JOURNAL 292:605-608 (1993)]. age−1 mutants show a lower rate of
deletions in the mitochondrial genome than wild-types [NUCLEIC ACID
RESEARCH 23(8):1419-1425 (1995)]. <B><I>C. elegans</I></B> homozygous
for nonsense <B>age−1</B> gene mutations have shown a ten-fold increase
in maximum lifespan [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/17996009"
TARGET="_blank">AGING CELL; Ayyadevara,S; 7(1):13-22 (2008)</A>].
<P>Nematodes normally live under the soil where oxygen concentrations are 1%
to 2%, suggesting that the higher levels of antioxidant enzymes may only be
of advantage as an adaptation to the atmospheric oxygen (21% oxygen) of
laboratory conditions. When age−1 mutants are raised under more natural conditions
of low food-availability they die more quickly than wild-type [NATURE
405:296-297 (2000)].
<P><B><I>C. elegans</I></B> <B>age−1</B> was later
identified [<A HREF="http://www.genetics.org/content/143/3/1193.long"
TARGET="_blank">GENETICS; Malone,EA; 143(3):1193-1205 (1996)</A>].
as <B>daf−23</B>,
part of the gene family including the <B>daf−2</B>
(<B>DA</B>uer <B>F</B>ormation gene) mutation of which causes the nematode to go
into the developmentally arrested <B>dauer</B> state (from the German
<B><I>dauern</I></B>, meaning "to endure"). The daf−2 DNA gene sequence
most resembles the mammalian gene for the
<B><a href="../nutrceut/GH_IGF1.html" TARGET="_blank">IGF1−1</a></B> (<B>Insulin-like Growth
Factor−1</B>) receptor, but is also quite similar to the <B>insulin</B> receptor.
(In <B><I>C. elegans</I></B> the single daf−2 receptor corresponds in function
to the two mammalian receptors — insulin and IGF−1.) The <B>age−1</B> gene product
is a signaling kinase which acts downstream of the <B>daf−2</B> receptor.
<P>The dauer state is
naturally seen among <B><I>C. elegans</I></B> larvae under conditions
of low food availability. The dauer is non-feeding, non-reproductive and
resistant to damage from ionizing radiation, extreme temperature &
free-radicals ("stress-resistant"). If conditions improve, the
dauer moults to a normal adult state. Autophagy genes are essential for dauer
formation and are essential for the lifespan increase associated with
dauer [SCIENCE; Melendez,A; 301:1387-1391 (2003)].
<P>Dauer larvae do not feed and the time
spent in a quiescent state of reduced metabolism ("suspended animation")
may not count as life extension. Some ticks stop metabolizing if they cannot eat, and
can survive in a quiescent state for years. <B><I>Drosophila</I></B> cooled from
25ºC to 15ºC live more than 3 times
longer [<A HREF="http://www.jbc.org/cgi/reprint/32/1/103"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; 32(1):103-121 (1917)</A>] — a
temperature reduction which should be associated with a halving of metabolic rate.
<P>Among other effects, Daf proteins
reduce fertility & movement of <B><I>C. elegans</I></B> while shifting metabolism toward the breakdown
of fat — analogous to the metabolic shift seen in humans when insulin levels
fall off. But the lifespan increases of the dauer state are not entirely due to
reduced metabolism — increased antioxidant enzyme levels and more stress-resistance
proteins play a role. Strong reduction of function mutations to <B>daf−2</B> or
<B>age−1</B> (the "insulin/IGF−1 pathway") cause the dauer state, whereas
weak mutations simply cause a more quiescent phenotype having dauer-like qualities of
increased antioxidant enzymes, extended lifespan and lower metabolic
rate [<A HREF="http://www.pnas.org/cgi/content/full/96/20/11399"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); van Voorhies,WA;
96(20):11399-11403 (1999)</A>]. In particular, <B>daf−2</B> mutations increase Mn−SOD
expression in the mitochondria [<A HREF="http://www.fasebj.org/cgi/content/full/13/11/1385"
TARGET="_blank">THE FASEB JOURNAL; Honda,Y; 13(11):1385-1393 (1999)</A>].
<p>Not only are daf−2
mutations associated with increased catalase, but <B><I>C. elegans</I></B> with defective
peroxisomal catalase genes have been proposed as models of "accelerated
aging" [<A HREF="http://www.jbc.org/cgi/content/full/279/19/19996"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Petriv,OI; 279(19):19996-20001 (2004)</A>].
Some daf−2 mutants display the same phenotype, but
without reduced fertility [<A HREF="http://www.genetics.org/cgi/content/full/150/1/129"
TARGET="_blank">GENETICS; Gems,D; 150(1):129-155 (1998)</A>]. Removal of gonads from
<B>daf−2</B> reduction-of-function nematodes increased lifespan even more than the
reduction of <B>daf−2</B> function [SCIENCE; Arantes-Oliveira,N; 302:611 (2003)].
<B><I>C. elegans</I></B> on CRAN get further life extension with <B>daf−2</B>
mutations, indicating that CRAN and insulin/IGF−1 defects extend lifespan by different
mechanisms [EXPERIMENTAL GERONTOLOGY; Houthoofd,K; 38(9):947-954 (2003)
and <A HREF="http://www.pnas.org/cgi/content/full/95/22/13091"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Lakowski,B;
95(22):13091-13096 (1998)</A>].
<P>Reduced expression of daf−2 or age−1 cannot induce the dauer state or extend lifespan
without the <B>Daf−16</B> transcription factor, which is downstream from the other two
proteins. The signalling dependency is:
<P><B>daf−2 -> age−1 -> PKB -> Daf−16</B>
<P>where PKB is <B>P</B>rotein <B>K</B>inase <B>B</B>. Note that the dependency
relationship is such that high "insulin signalling" (high daf−2/age−1 expression)
leads to low Daf−16 activity, whereas defective mutations of daf−2/age−1 (or starvation)
leads to high Daf−16 transcription activity, which causes the dauer-like lifespan extension.
<P>A table summarizes the homologous proteins between <B><I>C. elegans</I></B> and
mammals:
<P>
<TABLE BORDER=7 CELLSPACING=3 CELLPADDING=3>
<CAPTION><B>Homologous Proteins (Gene products) </B>
<TR><TD><B><I>C. elegans</I></B></TD><TD><B>daf−2</B></TD><TD><B>age−1</B></TD>
<TD><B>PKB</B></TD> <TD><B>Daf−16</B></TD> <TD><B></B></TD> <TD><B>Daf−18</B></TD> </TR>
<TR><TD><B>mammals</B></TD><TD><B>Ins/IGF−1</B></TD><TD><B>PI3K</B></TD>
<TD><B>Akt</B></TD><TD><B>FOXO</B></TD> <TD><B></B></TD> <TD><B>PTEN</B></TD> </TR>
</TABLE>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>PI3K blocks Daf−16 longevity</B></CAPTION>
<TR><TD WIDTH="400">
<img src="Daf2Path.jpg" width="400" height="420" alt="PI3K blocks Daf−16 longevity">
</TR></TD>
</TABLE>
<P>Mammalian homologs to the <B><I>C. elegans</I></B> genes/proteins
are the subject of intense interest concerning possible regulation of mammalian
lifespan. As has been mentioned, the <B><I>C. elegans</I></B> <B>daf−2</B> receptor
acts like a mammalian insulin/IGF−1 receptor. <B><I>C. elegans</I></B> <B>age−1</B>
corresponds in mammals to the inositol lipid kinase
<B>PI3K</B> (<B>P</B>hosphatidyl<B>I</B>nositol <B>3</B>−<B>K</B>inase). Mammalian protein
kinase B (<B>PKB</B>) is also called <B>Akt</B> (a kinase activated by phosphorylation of
serine and/or threonine residues). <B>Daf−16</B> corresponds to the mammalian family of
transcription factors called <B>FOXO</B> (<B>F</B>orkhead b<B>OX</B> class <B>O</B>),
which regulates stress response. When FOXO proteins are
phosphorylated by protein kinase B they are excluded from the nucleus and degraded
upon ubiquitination. <B>Daf−16/FOXO</B> gene transcription can lead to DNA-repair stimulation,
(<A HREF="../health/cancer.html#cellcycle" TARGET="_blank">cell cycle</a> arrest,
apoptosis, and induction of heat shock proteins & anti-oxidant enzymes [SCIENCE;
Brunet,A; 303:2011-2015 (2004)]. Variations in FOXO genetics has a significant effect
on human lifespan [<A HREF="http://www.nature.com/ejhg/journal/v15/n3/full/5201766a.html"
TARGET="_blank">EUROPEAN JOURNAL OF HUMAN GENETICS; Kuningas,M; 15(3):294-301 (2007)</A>].
Stress signals from JNK MAPKs exert their effects through
<B>Daf−16/FOXO</B> in parallel with insulin/IGF−1
signalling [<A HREF="http://www.pnas.org/cgi/content/full/102/12/4494"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Oh,S; 102(12):4494-4499 (2005)</A>].
<P>In sum, when the <B>daf−2/insulin/IGF−1 pathway</B> is intact, <B>age−1/PI3K</B>
phosphorylation of <B>Daf−16/FOXO</B> prevents that protein from entering the nucleus
to activate defensive/hibernation "longevity genes".
<P>The mammalian PI3K/Akt pathway activates cell growth & proliferation while at the same time
promoting cell survival by inhibiting macroautophagy and
apoptosis [<A HREF="http://www.jbc.org/cgi/content/full/276/38/35243"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Arico,S; 276(38):35243-35246 (2001)</A>].
<B>PTEN</B> normally dampens the PI3K/Akt pathway, thereby acting as a tumor-suppressor.
By inactivation of the tumor suppressor protein <B>PTEN</B>, oxidative stress
activates PI3K — resulting in PKB/Akt promotion of
proliferation [<A HREF="http://www.nature.com/emboj/journal/v22/n20/full/7590924a.html"
TARGET="_blank">THE EMBO JOURNAL; Leslie,NR; 22(20):5501-5510 (2003)</A>]. PI3K activation
increases expression of ARE (<A HREF="../nutrceut/AntiOxidants.html#enzymes"
TARGET="_blank">Antioxidant-Responsiveness Element)</A> genes leading to the synthesis of more
<A HREF="../nutrceut/AntiOxidants.html#enzymes" TARGET="_blank">antioxidant enzymes</A>.
<B>PTEN</B> mutations that inactivate <B>PTEN</B> expression allow unrestrained activity
of PI3K/Akt, which often leads to
cancer [<A HREF="http://www.medscimonit.com/pub/vol_10/no_10/6275.pdf"
TARGET="_blank">MEDICAL SCIENCE MONITOR; Chu,EC; 10(10):RA235-RA241 (2004)</A>]. The mammalian
<B>PTEN</B> gene corresponds to the <B><I>C. elegans</I></B> <B>daf−18</B> gene.
Mutations in <B>daf−18</B>
can suppress the dauer phenotype and longevity induced by <B>daf−2</B> or <B>age−1</B>
inactivation [<A HREF="http://www.pnas.org/cgi/content/full/96/13/7427"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Mihaylova,VT;
96(13):7427-7432 (1999)</A>].
<P>(Human atherosclerotic plaques contain a high proportion of senescent cells, probably because
of increased p53-induced senescence as a result of <B>Akt</B> phosphorylation by insulin
— underlying the relationiship between diabetes and atherosclerosis. These senescent cells
produce high levels of proinflammatory molecules that promote atherogenesis. Inhibition of
<B>FOXO3</B> by <B>Akt</B> is an essential factor in the senescent growth
arrest [<A HREF="http://embojournal.npgjournals.com/cgi/content/abstract/23/1/212"
TARGET="_blank">THE EMBO JOURNAL; Miyauchi,H; 23(1):212-220 (2004)</A>].)
<p>The mammalian PI3K/Akt pathway can be inhibited by rapamycin, which inhibits the kinase <b>mTOR/TOR</b>
— <a href="http://en.wikipedia.org/wiki/Mammalian_target_of_rapamycin" target="_blank">(mammalian)
Target Of Rapamycin</a>. Inhibition of mTOR by rapamycin or calorie restriction triggers
macrophagy. <B><I>Drosophila</I></B> fed rapamycin have shown extended
lifespan [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824086/"
TARGET="_blank">CELL METABOLISM; Bjedov,Z; 11(1):35-46 (2010)</A>] and rapamycin has
the same effect on mice [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786175/
TARGET="_blank">NATURE; Harrison,DE; 460:392-396 (2009)</A>]. Changes in the expression of
genes controlled by Tor, Ras, and Sch9 in yeast causes a switch to glycerol calorie
source — extending
lifespan [<A HREF="http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1000467"
TARGET="_blank">PLOS GENETICS; Wei,M; 5(5):e1000467 (2009)</A>]. (For more information
on the PI3K/Akt pathway see <a href="../health/cancer.html#signalling"
target="_blank">Signalling Molecules and Transcription Factors</a>.)
<P>In <B><I>Drosophila</I></B> a defective <B>chico</B> "insulin/IGF−1 signalling
gene" has been shown to increase lifespan 48%, reduce fertility and increase
antioxidant enzymes and produce a fly that is half the size of wild-type
flies [SCIENCE; Clancy,DJ; 292:104-106 (2001)]. <B>Chico</B> mutants have fewer cells
and smaller cells [CELL; Bohni,R; 97(7):865-875 (1999)]. As with
<B><I>C. elegans</I></B>, the single insulin/IGF−1 receptor in
<B><I>Drosophila</I></B> is believed to correspond with the distinct (but similar)
insulin and IGF−1 receptors in humans. <B>Chico</B> protein corresponds to the mammalian
Insulin Receptor Substrate (<B>IRS</B>) "docking protein" that is
associated with the IGF−1 receptor, so defective mutations result in a similar effect as
defective <B>daf−2/age−1/Insulin/IGF−1</B> signalling.
<P> The <B><I>C. elegans</I></B> gene <B>clk−1</B> (the
"clock" gene), alters growth rate, cell cycle time and other
"timed" events in the nematode life-cycle. Defective
clk−1 genes reduce metabolism and extend lifespan, whereas
overexpression of clk−1 reduces lifespan. The sluggish clk−1
mutants are defective in <A HREF="../nutrceut/CoEnzymeQ.html"
TARGET="_blank">Coenzyme Q</A> synthesis (essential
for mitochondrial energy generation) and when they are fed bacteria that do not
supply CoEnzyme−Q their development
arrests [<A HREF="http://www.pnas.org/cgi/content/full/98/2/421"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA) 98(2):421-426
(2001)</A>], and they revert to anaerobic metabolism that
produces less energy while avoiding much of the free radical generation associated
with oxidative phosphorylation [SCIENCE; Larsen, PL; 295:120-123 (2002)].
<p> <B><I>C. elegans</I></B> lifespan extension has been achieved by
mitochondrial function inhibition [SCIENCE;Dillin,A; 298:2398-2401 (2002)].
<B><I>C.elegans</I></B> given anti-oxidant compounds that mimic the action of both
superoxide dismutase and catalase show significant increases
in mean and maximum lifespan [SCIENCE; Melov,S; 289:1567-1569 (2000)]. Nematode
daf−2/age−1 impairment only increases lifespan when the defect occurs in neurons, not
muscle or intestine — possibly because neurons are more vulnerable to
free-radicals [SCIENCE; Wilkow,CA; 290:147-150 (2000)]. The <B>HSF−1</B>
transcription factor (Heat Shock Factor, which regulates heat shock response) has been
shown to be essential for Daf−16 induced longevity in <B><I>C.elegans</I></B>.
Reduced activity of <B>HSF−1</B> reduces lifespan and additional <B>HSF−1</B>
gene copies have increased lifespan by 40%. Small heat shock proteins which can
inhibit toxic protein aggregation seem to be the key to this effect [SCIENCE; Hsu,A;
300:1142-1145 (2003)].
<p>Similarly, <B><I>Drosophila</I></B> bred for longevity have displayed increased
levels of small heat shock proteins [JOURNALS OF GERONTOLOGY; Kurapati,R;
55A(11):B552-B559 (2000)]. Overexpression of small heat shock proteins in
<B><I>Drosophila</I></B> has been shown to extend their lifespan by
30% [<A HREF="http://www.pnas.org/cgi/content/full/101/34/12610"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Wang,H; 101(34): 12610-12615(2004)</A>].
<p>A number of mutations can produce the effects of CRAN by indirect means. For example, the
<b>eat</b> mutations in <B><I>C. elegans</I></B> result in reduced efficiency of
the pharynx to pump food [<A HREF="http://www.genetics.org/cgi/content/full/166/1/161"
TARGET="_blank">GENETICS; McKay,JP; 166(1):161-169 (2004)</A>]. More subtly, the <b>Indy</b>
(I'm Not Dead Yet) mutation in <B><I>Drosophila</I></B> results in defective membrane
transport of Krebs cycle intermediates [SCIENCE; Rogina,B; 290:2137-2140 (2000)].
<p>Metabolic rate is not reduced in <B><I>C. elegans</I></B> <B>daf−2</B> mutants
having extended lifespan, but efficiency of oxidative phosphorylation is increased [AGING
CELL; Braeckman,BP; 1(2):82-88 (2002)]. Nor is metabolic rate reduced in <B><I>Drosophila</I></B>,
either in CRAN or defective insulin/IGF−1 signalling (<b>chico</b> mutants) having extended
lifespan [EXPERIMENTAL GERONTOLOGY; Hulbert,AJ; 39(8):1137-1143 (2004)]. Cohorts of
<B><I>Drosophila</I></B> with no obvious genetic defects can have up to a five-fold difference
in lifespan with no significant difference in metabolic rate [EXPERIMENTAL GERONTOLOGY;
Hulbert,AJ; 39(8):1137-1143 (2004) and <A HREF="http://jap.physiology.org/cgi/content/full/95/6/2605"
TARGET="_blank">JOURNAL OF APPLIED PHYSIOLOGY; van Voorhies,WA; 95(6):2605-2613 (2003)</A>].
<P><a href="#contents"> (return to contents)</a>
<H3><a name="longevity2">XVI. LONGEVITY GENES (MAMMALS)</a></H3>
<P>Mice (and other mammals) have distinct insulin and
<a href="../nutrceut/GH_IGF1.html" TARGET="_blank">IGF1−1</a> receptors, unlike flies and
worms, that have a single insulin/IGF−1-like receptor. But defects of either of these
receptors have been shown to result in a lifespan increase for mice. Insulin resistance is
associated with diabetes and is even recommended as a biomarker of aging — so it is
mysterious why blocked insulin signaling can extend lifespan. Fat-specific Insulin Receptor
Knock-Out (<B>FIRKO</B>) mice have reduced fat mass, normal calorie intake and an increased
maximum lifespan of 18% [SCIENCE; Bluher,M; 299:572-574 (2003)]. Yet deletion of
all insulin receptor genes in mice results in neonatal death [EMBO JOURNAL; Joshi,RL;
15(7):1542-1547 (1996)].
<P> Two single gene mutations on mice — one on chromosome 11 (<b>Prop−1</b> locus,
<b>Ames dwarf</b>) and the other on chromosome 16 (<b>Pit−1</b> locus,
<b>Snell dwarf</b>) — extend
mean & maximum lifespan significantly. Snell dwarfs have a defective pituitary transcription
factor which is downstream from the protein which is defective in Ames dwarfs. Both mutations
preclude normal development of the anterior pituitary. In both cases the adults are one-third
the size of normals and in both cases there are defects in production of <B>Growth
Hormone</B> (<B>GH</B>), prolactin and <B>Thyroid-Stimulating
Hormone</B> (<B>TSH</B>). Comparable to nematode daf−2/age−1 mutants, dwarf mice
have impaired IGF−1/insulin sensing pathways.
<P>Insulin-like Growth Factor−1 (IGF−1) is a mitogen and an important
mediator of the GH effect. The dwarf mice have greatly diminished IGF−1 blood
levels. Dwarf mice have higher antioxidant enzyme activity, lower body temperature and
reduced metabolism [JOURNALS OF GERONTOLOGY 56A(8):B340-B349 (2001)] as well as delayed
collagen cross-linking and delayed immune (T−cell)
aging [<A HREF="http://www.pnas.org/cgi/content/full/98/12/6736"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Flurkey,K;
98(12):6736-6741 (2001)</A>]. Fibroblasts from
Snell Dwarf mice have great resistance to injury by heat, hydrogen peroxide, cadmium,
UV light and paraquat [FASEB JOURNAL 17:1565-1566 (2003)] — a similar
stress-resistant pattern as is seen in <B>daf−2</B>/<B>age−1</B> mutants. Kidney disease
is common in rodents, but this is not the case for dwarfs.
<P>The slope of the survival curves of dwarf mice match those of controls, indicating that
the rate of aging is not changed — rather the curve has been shifted to the right,
possibly due to slower development time to maturity. Ames dwarfs develop tumors at the same
frequency as wild-types, but at a later age [JOURNAL OF THE AMERICAN AGING ASSOCIATION;
Mattison,JA; 23:9-16 (2000)]. CRAN, by contrast, reduces the slope of
the survival curve. The fact that the lifespan of Ames Dwarf mice can be further extended by
CRAN [NATURE; Barke,A; 414:412 (2001)] shows that the mechanism of lifespan extension
in dwarfism is at least partially distinct from that of CRAN. Ames Dwarf mice show a
significantly delayed occurrence of <A HREF="../health/cancer.html" TARGET="_blank">cancer</A>
compared to normal mice [JOURNALS OF GERONTOLOGY; Ikeno,Y; 58A(4):B291-B296 (2003)] —
probably because IGF−1 promotes apoptosis in unanchored cells (notably, cancer cells) and
is anti-apoptotic in other cells.
<P>"Knockout mice" (ie, mice with genes "knocked out") lacking GH show
significantly reduced IGF−1 and thyroid hormone. The knockout mice are one-third normal
weight and show a 60% lifespan extension (comparable to those of dwarf
mice) [<A HREF="http://endo.endojournals.org/cgi/content/full/141/7/2608"
TARGET="_blank">ENDOCRINOLOGY; Coschigano,KT; 141(7):2608-2613 (2000)</A>]. As with Ames dwarfs,
insulin sensitivity is greater and plasma glucose & insulin may be reduced, resulting in
less <A HREF="#protein" TARGET="_blank">glycation</A> [JOURNALS OF GERONTOLOGY;
56A(8):B340-B349 (2001)]. Although knockout mice for IGF−1 are not viable, mice with half
their IGF−1 genes knocked-out (heterozygous knockouts) live 26% longer and show
resistance to oxidative stress without dwarfism, altered fertility or altered
metabolism [NATURE; Holzenberger,M; 42:182-187 (2003)].
<P>Mice with defective <B>p66<SUP>shc</SUP></B> gene resist apoptosis caused by paraquat,
hydrogen peroxide and UV light. The mice show a 30% increase in lifespan (less than
the lifespan increase in dwarf mice [NATURE; Migliaccio,E; 402:309-313 (1999)]. The
<B>p66<SUP>shc</SUP></B> signal transduction pathway is activated by oxidative stress and
leads to apoptosis. Apoptosis due to oxidative stress is mediated by p53, and antagonized by
p21 (presumably sometimes by a p53-independent pathway in which <B>p66<SUP>shc</SUP></B>
participates). The <B>p66<SUP>shc</SUP></B> protein increases cellular oxidative stress as
a defense against infectious agents (lab mice are protected from pathogens). The
<B>p66<SUP>shc</SUP></B> mutant mice do not survive well in cold (lab mice are kept warm).
The <B>p66<SUP>shc</SUP></B> protein is downstream from the
IGF−1 receptor and is underphosphorylated in dwarf mice [HORMONE RESEARCH; Hozenberger,M;
62(Suppl 1):89-92 (2004)]. The protein is an activator of the <B>Ras</B> mitogen receptor.
<P>Overexpression of the <B>klotho</B> gene extends the maximum lifespan of male mice about 20%,
but has little effect on females. Males have reduced insulin sensitivity, but females do not. Despite
resistance to both insulin & IGF−1, the mice have normal size & food intake, but
fertility is reduced [SCIENCE; Kurosu,H; 309:1829-1833 (2005)].
<P>Reduced body size within a species often correlates with longer lifespan and reduced plasma IGF−1.
Great Danes (400 ng/mL plasma IGF−1) live about 7 years, whereas
Chihuahuas (40 ng/mL plasma IGF−1) can live over 15 years. Does low IGF−1
causing small body size lead to greater longevity — or is the smaller body size due to
reduced IGF−1 irrelevant to life-extension resulting from IGF−1 signalling? Ironically,
GH (and therefore, IGF−1) hormone replacement is touted as an anti-aging, rejuvenating
remedy for older humans — including such claimed benefits as improved cognition &
improved immune function (benefits attributed to <I><B>reduced</B></I> IGF−1 in mice).
<P>It may be that high GH/IGF−1 is an example of "antagonistic pleiotrophy".
Larger animals with greater fertility and short lifespans are likely to be dominant in
an environment where successful competition with other animals is the key to survival. In
environments with scarce resources, but little competition, smaller size with reduced
fertility & greater longevity may result in more surviving offspring.
<P>High GH and IGF−1 increases tissue development, metabolism and glucose utilization
at the cost of higher oxidative stress, more protein glycation and higher proliferation.
It may well be most conducive for survival to have high GH/IGF−1 during development, but
reduced GH/IGF−1 levels after maturation. From this point of view, GH replacement in
adults may not be a good idea.
<P>Within mammalian species, small size is associated with greater longevity when the small
size is not due to inadequate nutrition. If DNA repair capability increases for larger species,
but is the same for larger members of the same species (who have more cells), then the larger
animals may be more vulnerable to tissue degeneration and cancer than the smaller members of
the same species. Dwarf mice and smaller breeds of dogs have less
Insulin-like Growth Factor−1 (IGF−1) and are less vulnerable to cancer [JOURNALS
OF GERONTOLOGY 51A(6):B403-B408 (1996)]. But if CRAN and IGF−1 reduction are a famine-like
trigger of the same defensive metabolism in the organism — more heat shock protein, more
antioxidant enzymes, greater DNA repair and reduced fertility (it would be wasteful to use
resources on producing offspring who have little chance of surviving) — then additive
effects of both would not be expected.
<P>To say that IGF−1 and cell-signalling regulate aging is a half-truth — with the
missing half required to explain the mechanisms of aging. What lies at the end of the
cell signalling? The answer must be more antioxidant enzymes, more heat shock proteins
and/or better DNA repair — and/or fewer harmful agents like cortisol and inflammatory
cytokines. Aging is ultimately accumulated damage on the macromolecular,
cellular and tissue level — ultimately the result of a limited number of possible defenses
and a limited number of possible damaging agents. "Longevity genes" must result in
decreased aging-damage or increased aging-damage repair. Although means may be found to enhance
defenses to slow aging, the ultimate challenge is to find means to <B>repair</B> the damage.
<P>(See <A HREF="../nutrceut/GH_IGF1.html" TARGET="_blank">Growth Hormone (GH/IGF−1) Replacement</A>
for more about GH and IGF−1.)
<P><a href="#contents"> (return to contents)</a>
<H3><a name="silencing">XVII. SIRTUINS AND DEACETYLASES IN AGING </a></H3>
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Sir2 deacetylates protein <br>with NAD<sup>+</sup> as a co-factor</B></CAPTION>
<TR><TD WIDTH="300">
<img src="Sir2_NAD.jpg" width="300" height="250" alt="Sir2 deacetylates protein with NAD<sup>+</sup> as a co-factor">
</TR></TD>
</TABLE>
<P>(For background on gene silencing by histone deacetylation, see
<A HREF="../health/cancer.html#epigenetic" TARGET="_blank">Epigenetic Dysregulation</A>.)
<P> Like <B><I>Drosophila</I></B> and <B><I>C. elegans</I></B>, the budding yeast
<B><I>Saccharomyces cerevisiae</I></B> (Brewer's yeast) has served as a model organism for aging research.
Of interest has been the <B><I>S. cerevisiae</I></B> <B>S</B>ilent <B>I</B>nformation
<B>R</B>egulator (<B>SIR2</B>) gene which produces the <B>Sir2</B> histone deacetylase
protein. Acylation of histones reduces their binding to DNA, thereby facilitating transcription,
whereas deacylation allows histones to bind to DNA thereby silencing gene expression.
<b>Replicative lifespan</b> in yeast refers to the lifespan of a "mother" cell
that buds-off "daughter" cells. The number of daughter cells that a mother
produces before it "dies of old age" is called the replicative lifespan. The
major cause of replicative aging is the "toxic" extra-chromasomal rDNA circles
which segregate and accumulate in the mother cell. Yeast with SIR2 deletions have a short lifespan,
whereas yeast with extra SIR2 genes have greatly extended lifespan [CELL; Longo,VD;
126(2):257-268 (2006)]. Gene silencing by deacetylation causes the
chromatin to become more closed & inaccessible, thereby reducing
genome instability [<A HREF="http://www.genesdev.org/cgi/reprint/14/9/1021"
TARGET="_blank">GENES & DEVELOPMENT; Guarente,L; 14(9):1021-1026 (2000)</A>].
<p>Yeast cells cease to divide under conditions of nutrient deprivation (severe calorie
restriction). The survival of yeast under such conditions has been called
<b>chronological lifespan</b> — and is regarded as a model for mammalian post-mitotic
cells, in contrast to replicative lifespan, which is regarded as a model for mammalian
proliferative cells. Deletion of SIR2 in yeast increases stress resistance and
increases chronological lifespan when calories are
restricted [<A HREF="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17530929"
TARGET="_blank">PLoS GENETICS; Kaeberlein,M; 3(5):e84 (2007)</A>].
<p>SIR2 expression is activated by CRAN
(<A HREF="../calories/calories.html" TARGET="_blank">Caloric Restriction with
Adequate Nutrition</A>), but neither CRAN nor extra SIR2 can silence genes without <B>NAD+</B>
(oxidized form of <B>N</B>icotinamide <B>A</B>denine <B>D</B>inucleotide) as a
co-factor [SCIENCE 289:2126-2128 (2000)]. The presence of a high NAD/NADH ratio in a
cell is an index of low energy production. CRAN yeast
with less NAD do not show greater longevity than ad-libitum fed yeast. The <b>PNC1</b> gene
encodes an enzyme which deaminates nicotinamide, and may be the upstream transducer of a
variety of low-intensity, longevity-activating stressors, including heat, osmosis and CRAN
— suggesting that life extension due to SIR2 is a generalized stress response [NATURE;
Anderson,RM; 423:181-185 (2003)].
<P>Insofar as genetic instability (ribosomal DNA recombination, in particular) seems to be
the primary (fastest) "aging" mechanism in yeast, it is not surprising that gene
silencing extends yeast lifespan. But ribosomal DNA is far more stable in higher organisms.
<P>In <B><I>C. elegans</I></B> <b>sir−2.1</b> — the gene most similar in DNA sequence
to yeast SIR2 — inactivates the receptor for the nematode version of insulin — thereby
activating Daf−16 protein production. Again, NAD+ is a necessary co-factor.
Doubling the <b>sir−2.1</b> gene in <B><I>C. elegans</I></B> apparently resulted in a 50%
extension of lifespan [NATURE; Tissenbaum,HA; 410:227-230 (2001)].
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>LONGEVITY GENES AND DNA REPAIR<B></CAPTION>
<TR><TD WIDTH="500">
<img src="DNArepairGenes.jpg" width="500" height="600" alt="image by Harold Brenner">
</TR></TD>
</TABLE>
<P>Experiments in which <B><I>Drosophila</I></B> <B>Sir2</B> expression was quadrupled
apparently led to a 57% extension of lifespan, with no further lifespan extension by CRAN.
Flies on CRAN showed an increase in Sir2 mRNA and a lifespan increase that could be
prevented by decreasing Sir2 gene
function [<A HREF="http://www.pnas.org/cgi/content/full/101/45/15998"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Rogina,B;
101(45):15998-16003 (2004)</A>]. <B><I>Drosophila</I></B> fed the histone
deacetylase inhibitor 4-phenylbutyrate showed up to 52% longer maximum lifespan. Gene
analysis showed repressed expression of some metabolism genes and increased expression of
genes for SOD, Elongation Factor−1-alpha (EF−1 α) & heat shock proteins,
among others [<A HREF="http://www.pnas.org/cgi/content/full/99/2/838"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Kang,H; 99(2):838-843
(2002)</A>].
<p>In contrast to earlier research, however, a more careful analysis
of Sir2 overexpression in <B><I>C. elegans</I></B> and
<B><I>Drosophila</I></B> either showed no increase in
lifespan [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/21938067"
TARGET="_blank">NATURE; Burnett,C; 477:482-485 (2011)</A>],
or a more modest 10-13% increase in
lifespan [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/21938026"
TARGET="_blank">NATURE; Viswanathan,M; 477:E1-E2 (2011)</A>].
<P>Deacetylation of proteins (other than histones) can directly modify their activity.
Most mammalian histone deacetylase enzymes are not
NAD-dependent [<A HREF="http://www.jstage.jst.go.jp/article/jphs/98/3/98_200/_article"
TARGET="_blank">JOURNAL OF PHARMACEUTICAL SCIENCES; Hisahara,S; 98(3):200-204 (2005)</A>].
A family of
NAD-dependent Sir2-like deacetylases in mammals called <B>sirtuins</B> includes SIRT1
in the nucleus, SIRT2 in the cytoplasm and SIRT3 in the mitochondria. The protein most
resembling yeast SIR2 in humans is <B>SIRT1</B>. Unlike yeast Sir2 (which exclusively
deacetlyates histones) SIRT1 has a wide range of
substrates [<A HREF="http://genesdev.cshlp.org/content/20/21/2912"
TARGET="_blank">GENES & DEVELOPMENT; Haigis,MC; 20(21):2912-2921 (2006)</A>]
including <A HREF="https://en.wikipedia.org/wiki/TP53" TARGET="_blank">p53</A>
and <A HREF="https://en.wikipedia.org/wiki/TP53" TARGET="_blank">FOXO3 protein</A>
which SIRT1 silences by direct deacylation —
reputed to prevent "premature senescence"
and "premature apoptosis". Nonetheless, SIRT1 deacetylation of p53 has not
been shown to alter cell survival following DNA
damage [<A HREF="http://mcb.asm.org/cgi/content/full/26/1/28"
TARGET="_blank">MOLECULAR AND CELLULAR BIOLOGY; Solomon,JM; 26(1):28-38 (2006)</A>].
<P>Polyphenols such as <A HREF="../nutrceut/phytochemicals.html#quercetin"
TARGET="_blank">quercetin</A>,
<A HREF="../nutrceut/phytochemicals.html#resveratrol" TARGET="_blank">resveratrol</A>
(especially) and other sirtuin-activating compounds have been reported to extend the
lifespan of nematodes & fruit flies. Resveratrol was shown to extend lifespan of
nematodes by 10% and fruit flies by 29% without loss of fertility [NATURE;
Wood,JG; 430:686-689 (2004)]. No lifespan increase was seen in flies lacking functional
<B>Sir2</B> and no additional life extension was seen with CRAN. This led to the conclusion
that (unlike <B><I>C. elegans</I></B> <B>daf−2</B> mutations), the life-extending
benefits of <b>Sir2</b> operate by a similar mechanism as CRAN. But there is experimental
evidence contradicting this conclusion [SCIENCE; Kaeberlein,M; 312:1312 (2006)].
<p>Resveratrol has also been shown to extend the lifespan of short-lived fish
(<A HREF="https://en.wikipedia.org/wiki/Killifish#In_lifespan_research" TARGET="_blank">killifish</A>)
nearly 60%
without loss of fertility [CURRENT BIOLOGY; Valenzano,OR; 16(3):296-300 (2006)], possibly
by increased sirtuin expression, but a number of other mechanisms are possible [MUTATION
RESEARCH; Kundu,JK; 555(1-2):65-80 (2004) and <A HREF="http://www.jbc.org/cgi/content/full/280/17/17038"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Kaeberlain,M; 280(17):17038-17045 (2005)</A>].
<p>Analysis of the brain, kidney, liver and other tissues of rats subjected to 60% <i>ad
libitum</i> CRAN showed increased SIRT1 expression [SCIENCE; Cohen,HY; 305:390-392 (2004)].
Treatment of human embryonic kidney cells with resveratrol or transfection of those cells with
SIRT1 expression vector resulted in a dose-dependent reduction of <b>Bax</b> protein mediated
apoptosis [SCIENCE; Cohen,HY; 305:390-392 (2004)]. SIRT1 increases FOXO3's induction
of cell cycle arrest and resistance to oxidative stress, but inhibits FOXO3's induction of
apoptosis [SCIENCE; Brunet,A; 303:2011-2015 (2004)].
<p>Methods of increasing NAD or activating sirtuins have been proposed to prevent
neurodegeneration [<A HREF="http://www.sciencemag.org/cgi/content/full/305/5686/1010"
TARGET="_blank">SCIENCE; Araki,T; 305(5686):1010-1013 (2004)</A>]. Neurons are post-mitotic
(as are all cells in fruit flies and nematodes) so the anti-apoptotic effect of SIRT1 would have
to be the main pro-survival mechanism. In response to DNA damage,
SIRT1 may inhibit p53-mediated cell-cycle
arrest and apoptosis, but in response to TNF−α cytokine reduces NF−κB mediated
inhibition of cell-cycle arrest and
apoptosis [<A HREF="http://www.nature.com/emboj/journal/v23/n12/full/7600244a.html"
TARGET="_blank">THE EMBO JOURNAL; Yeung,F; 23(12):2369-2380 (2004)</A>]. Resveratrol
similarly reduces NF−κB expression.
<p><B>Ku70</B> protein,
which functions in DNA repair, is normally bound tightly to <B>Bax</B> protein in the
cytoplasm, but in response to stress Ku70 is activated and releases Bax, which can then
move into the mitochondria to initiate apoptosis. SIRT1 reduces ku70 acetylation and thereby
opposes apoptosis [SCIENCE; Cohen,HY; 305:390-392 (2004)]. If SIRT1 were increasing
lifespan by resisting apoptosis, the effect would be similar to that seen in
p66<SUP>shc</SUP> mice. Human SIRT6 maintains telomere
integrity [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646112/"
TARGET="_blank">NATURE; Michishita,E; 452:492-496 (2008)</A>].
<p>Sirtuins facilitate NHEJ (Non-Homologous End-Joining DNA
repair mechanisms for Double-Strand Breaks, <b>DSB</b>s) by an unknown
mechanism [<A HREF="http://www.actabp.pl/pdf/1_2007/63.pdf"
TARGET="_blank">ACTA BIOCHIMICA POLONICA; Wojewodzka,M; 54(1):63-69 (2007)</A>].
ATM phosphorylation
of H2AX recruits SIRT1 to DSBs, which evidently assists in repair [CELL; Oberdoerffer,P;
135(5):907-918 (2008)]. Derepression of the genome at loci vacated by SIRT1 recruited by
genotoxic stress may lead to generalized dysdifferentiation associated with aging.
In vitro study of gene expression in neocortical tissue showed that more than two-thirds
of SIRT1-bound genes derepressed during aging were also derepressed by oxidative
stress [CELL; Oberdoerffer,P; 135(5):907-918 (2008)].
<p>SIRT1 also represses the nuclear receptor <b>PPAR−γ</b> (Peroxisome
Proliferator-Activated Receptor−gamma), thereby triggering lipolysis and
loss of fat, suggestive of the life-extending benefits of fat reduction in FIRKO
mice. Treatment of fibroblasts with the SIRT1 activator resveratrol resulted in a
significant reduction of fat content [NATURE; Picard,F; 429:771-776 (2004)].
PPAR−γ inhibition has been used to block the development of insulin
resistance due to obesity and type 2
diabetes [<A HREF="http://ajpendo.physiology.org/cgi/content/full/284/3/E618"
TARGET="_blank">AMERICIAN JOURNAL OF PHYSIOLOGY; Miles,PDG; 284(3):E618-E626 (2003)</A>],
suggestive of the idea that CRAN and the <a href="../health/MacroNut.html#syndrome"
target="_blank">metabolic syndrome</a> are opposite ends of a continuum.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="hormones">XVIII. HORMONES AND AGING </a></H3>
<P> A "neurohormonal clock" in the brain of mammals has been suggested
to influence aging through neurohormones.
Hormones alter the gene expression of DNA throughout the body. The
pituitary gland (the "master gland") under the influence of the
brain/hypothalamus can thus influence the physiology of all body cells.
When the pituitary gland of mammals is surgically removed and
supplements of essential hormones are given, maximum lifespan increases by
one third to one half. Such mammals voluntarily reduce their caloric intake,
which suggests that the life extension may be primarily due to CRAN
(<A HREF="../calories/calories.html" TARGET="_blank">Caloric Restriction with
Adequate Nutrition</A>).
<P> The hormones DHEA, melatonin, thyroid, and
somatotropin (Growth Hormone, <B>GH</B>) decline with
age. Women experience menopause, with the loss of progesterone and estradiol
secretion from the ovaries. Specific areas of the brain show
age-related declines in the levels of the neurotransmitters dopamine,
acetylcholine, norepinephrine, GABA and serotonin.
With aging there is a decline in both serotonin transporters [LIFE SCIENCES;
Yamamoto,M; 71(7):751-757 (2002)] and serotonin
receptors [<A HREF="http://www.nature.com/npp/journal/v18/n6/abs/1395175a.html;jsessionid=C90DC8D122AD01015378F209DDDC5B18"
TARGET="_blank">NEUROPSYCHOPHARMACOLOGY; Meltzer,MD; 71(7):751-757 (2002)</A>].
<A HREF="../science/anatmind/anatmd10.html#serotonin"
TARGET="_blank">Serotonin</a> is the precursor for melatonin in the brain.
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Decreased Anti-Diuretic Hormone (AVP) <br>effectiveness with age</B></CAPTION>
<TR><TD WIDTH="300">
<img src="./AVP_age.jpg" width="300" height="300"
alt="Decreased Anti-Diuretic Hormone (AVP) effectiveness with age">
</TR></TD>
</TABLE>
<p>Aging is associated with increasing secretion of the hormone
8−arginine vasopressin (<b>AVP</b>, also known as Anti-Diuretic Hormone or
simply vasopressin), and a decreasing ability of AVP to increase serum
<A HREF="../cryonics/protocol.html#diffusion"
TARGET="_blank">osmolality</A>. With age there is a decline in kidney AVP
receptors, which results in increased AVP secretion and decreased AVP
effectiveness [<A HREF="http://ajprenal.physiology.org/cgi/content/full/287/4/F797"
TARGET="_blank">AMERICAN JOURNAL OF PHYSIOLOGY; Tian,Y; 287(4):F797-F805 (2004)</A>].
Nearly 10% of the elderly suffer from
<a href="http://en.wikipedia.org/wiki/Hyponatremia" target="_blank">hyponatremia</a>,
and nearly twice as many elderly nursing home residents suffer from that
affliction [JOURNAL OF THE AMERICAN GERIATRIC SOCIETY; Miller,M;
54(2):345-353 (2006)].
<P> According to the <B>glucocorticoid cascade hypothesis</B>, glucocorticoid
steroid hormones show rising blood levels with age, which increasingly
damages feedback inhibition neurons in the
<A HREF="http://www.benbest.com/science/anatmind/anatmd3.html#hippo"
TARGET="_blank">hippocampus</A>, resulting in even
greater increases of blood glucocorticoid and a destructive feedback loop.
Glucocorticoid hormone (cortisol in humans) is a normal response to stress.
Cortisol mobilizes blood glucose and depresses the immune/inflammatory response,
among other effects. Although useful in emergencies, chronic stress can be
catabolic (destructive — Pacific salmon use glucocorticoids to self-destruct
after spawning). Physical & psychological stress causes the brain to release
<B>C</B>orticotropin <B>R</B>eleasing <B>F</B>actor (<B>CRF</B>) &
vasopressin — both of which stimulate pituitary release of
<B>A</B>dreno<B>C</B>ortico<B>T</B>ropic <B>H</B>ormone (<B>ACTH</B>).
ACTH causes the adrenal cortex to release glucocorticoids.
<P> High blood levels of glucocorticoids are sensed by neurons in the
hippocampus, which signal the brain to release less vasopressin. The
involvement of hippocampal neurons makes sense because stressful situations
are often associated with vivid & detailed memories. Patients with major
depression can lose 20% of their hippocampal volume. Cortisol can
reduce neuron uptake of glucose by 15-25% — which can contribute to
neuron death [EXPERIMENTAL GERONTOLOGY 34:721-732 (1999)]. Moreover,
glucocorticoids reduce cellular SOD & glutathione peroxidase activity
in all brain areas [BRAIN RESEARCH 791:209-214 (1998)].
<P> Although the glucocorticoid cascade hypothesis is not
a theory of aging in the sense of reducing lifespan, it does count as a theory
of brain aging — declining capacity for memory-formation in particular.
Blood glucocorticoid increases with age in rats, but humans normally do not
show increasing levels of glucocorticoid until the late 70s or 80s.
About half of
<A HREF="../lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's Disease</A>
patients show significantly elevated
cortisol, however. Most people do normally show
increasing number (and perhaps hypertrophy) of neurons in the
<B>P</B>ara<B>V</B>entricular <B>N</B>ucleus (<B>PVN</B>) — which
expresses both CRF & vasopressin — as they age. Evidence suggests
an inverted U−shaped relationship between cortisol & cognition — and
that sustained higher cortisol levels can lead to a non-Alzheimer's dementia
in humans [JOURNAL OF PSYCHIATRIC RESEARCH 35:127-145 (2001)]. Estrogen
can prevent or even reverse cortisol-induced brain damage [BRITISH
JOURNAL OF CLINICAL PHARMACOLOGY 52:647-653 (2001)].
<p>Much antioxidant protection in the brain is due to <b>bilirubin</b> which is produced
by <b>Heme Oxygenase</b> (<b>HO</b>) enzyme, particularly in the hippocampal neurons.
HO expression declines with age in the rat brain, and this decline has been linked
to elevated glucocorticoid expression [JOURNAL OF NEURAL TRANSMISSION; Ewing,JF;
113(4):439-454 (2006)]. Additionally, HO has antiapoptotic effects which are
independent of the antioxidant effects of bilirubin [KIDNEY INTERNATIONAL;
Nath,KA; 70(3):432-443 (2006)]. (For more on the antioxidant effects of bilirubin see
<a href="../nutrceut/AntiOxidants.html#enzymes" target="_blank">Antioxidant Enzymes</a>.)
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Some Hormone/Cytokine changes with age</B></CAPTION>
<TR><TD WIDTH="400">
<img src="Hormones.gif" width="400" height="400" alt="Some Hormone/Cytokine changes with age">
</TR></TD>
</TABLE>
<P> Some critics have pointed-out that CRAN animals show elevated glucocorticoids, but it
should come as no surprise that calorie-restriction is stressful. In fact, the glucocorticoid
cascade hypothesis raises the worrisome possibility that CRAN could prolong lifespan while
simultaneously undermining memory capabilities. But experiments on CRAN animals have not
shown learning deficiencies, quite the opposite.
<P>Humans and other primates are the only species that produce & secrete
the hormone <A HREF="../nutrceut/DHEA.html" TARGET="_blank">
<B>D</B>e<B>H</B>ydro<B>E</B>pi<B>A</B>ndrosterone</A> (<B>DHEA</B>)
and it's sulfate (<B>DHEA−S</B>) in quantities surpassing those of any other steroid.
DHEA levels peak in the late 20s and decline to 10% of the peak by age 80.
DHEA may protect against the harmful effects of cortisol while contributing to
androgen & estrogen synthesis in peripheral tissues, promoting lean body mass,
reducing depression and improving immune function [EXPERIMENTAL GERONTOLOGY
33(7/8):713&897 (1988)].
<P>Growth Hormone (<B>GH</B>) also declines with age (about 14% per decade after
age 25), which is blamed for increased fat deposition, loss of muscle mass and
bone demineralization. There is evidence that GH replacement can improve cardiovacular
health, boost immune function and improve cognitive function in older adults, but there
is also the danger that GH replacement can increase insulin resistance and cancer risk.
<P> The idea of restoring all hormones and growth factors to youthful levels
as a means of rejuvenation has a strong intuitive appeal, but hormones often have the
risk of promoting cancer growth. Given the fact that cancer incidence increases with
age, declining hormone levels may even contribute to elderly survival. Only
when cancer is eliminated will replacement of all age-declining hormones be safe.
Even then, however, for cases where declining receptor sensitivity rather that declining
hormone release are associated with age (as with AVP), hormone replacement will
not get to the root of the problem — and can be harmful without causing cancer.
<P>[For more about DHEA and GH, see <A HREF="../nutrceut/DHEA.html"
TARGET="_blank">DHEA Hormone Replacement</A> and <A HREF="../nutrceut/GH_IGF1.html"
TARGET="_blank">Growth Hormone (GH/IGF−1) Replacement]</A>.
<P>[For more about sex hormone replacement, see <A HREF="../health/SexHormR.html"
TARGET="_blank">Sex Hormone Replacement in Older Adults]</A>
<P><a href="#contents"> (return to contents)</a>
<H3><a name="immune">XIX. THE IMMUNE SYSTEM AND AGING </a></H3>
<P> According to the "immune system theory of aging", many aging
effects are due to the declining ability of the immune system to differentiate
"foreign" from "self" proteins. Not only does the immune system become less
capable of resisting infection & cancer, but declining cell function could
be due to attacks by the immune system against native tissues. Arthritis, psoriasis and
other autoimmune diseases increase with age. There is evidence
that histocompatability genes, genes affecting DNA repair and genes for SOD
production — all of which affect longevity — are located close together on human
chromosome 6.
<P>Leukocytes (white blood cells), which form the basis of the immune system (along with
complement proteins), are roughly 65% granulocytes (mostly neutrophils), 5% monocytes
(which can become macrophages) and 30% lymphocytes. Lymphocytes can be subclassified as
B−lymphocytes (<B>B−cells</B>) or T−lymphocytes (<B>T−cells</B>) based on whether they mature
in <B>B</B>one marrow or the <B>T</B>hymus gland (all lymphocytes originate in bone marrow).
<B>Antigens</B> are molecular portions of pathogens that act as identifiers.
<B>B−cells</B> generate antibodies ("humoral immunity") against antigens, whereas
<B>T−cells</B> directly bind to antigens ("cellular immunity").
<P> The thymus gland of the immune system reaches its greatest weight
during puberty, and shrinks thereafter, with lymphoid tissue being
replaced by fat. The shrinking of the thymus gland proceeds far more rapidly than the
progress of aging — at age 50 the thymus of humans is typically only 5−10%
of its original mass. Nonetheless, T−cells remain fairly constant over most of adult life
due to peripheral proliferation (although proliferation declines in the elderly).
<P>Because the thymus is the organ in which T−cells "matures", once
maturation occurs most of the work of the thymus is done. In the maturing T−lymphocyte
system, the thymus creates a broad diversity of T−cells, each of which is programmed to
recognize and combat a different antigen. T−cells which would combat self-substances
are eliminated by apoptosis.
<P>The immune system uses
<B><I>proliferation</I></B> & <B><I>apoptosis</I></B> to create & refine T−cells.
The immune system uses <B>clonal expansion</B> (rapid multiplication of lymphocytes
of a single "clone" against a single antigen) & apoptosis
to control the numbers of T−cells available to fight specific antigen threats.
Injecting the protein
<B><I>Apo−1</I></B> into a cell will trigger apoptosis. But the protein
<B><I>Bcl−2</I></B> can rescue a cell from apoptosis. With aging, mature T−cells
increasingly manifest apoptosis for reasons that seem to be unrelated to decreased
<B><I>Bcl−2</I></B> expression or oxidative stress [MECHANISMS OF AGING AND DEVELOPMENT;
Phelouzat,M; 88:25-38 (1996)].
<P>T−lymphocytes that have not encountered an antigen since creation
are called <B>naive T−cells</B>, whereas T−lymphocytes that have
been clonally expanded to fight an invading antigen are called
<B>memory T−cells</B>. T−cells of the elderly have a much higher ratio
of memory T−cells to naive T−cells than younger people. Old memory T−cells have
less <a href="http://en.wikipedia.org/wiki/CD28" target="_blank">CD28</a>
surface protein than young memory T−cells and are thus less able to divide when
presented with antigen [JOURNAL OF IMMUNOLOGY; Engwerda,CR; 152:3740-3747 (1994)]. CD28
ligation is required for production of IL−2 cytokines. The elderly
memory T−cells have short telomeres and are thought to accumulate because
of increasingly defective apoptosis [IMMUNOLOGIC RESEARCH 21(1):31-38 (2000)].
<P>Two predominant forms of T−cells are <B>cytotoxic T−cells</B> (with
<a href="http://en.wikipedia.org/wiki/CD8" target="_blank"><b>CD8</b></a>
surface receptors) and <B>helper T−cells</B> (with
<a href="http://en.wikipedia.org/wiki/CD4" target="_blank"><b>CD4</b></a> surface receptors).
The cytotoxic T−cells attack bacteria or cancerous cells by punching holes in
the cells and injecting them with toxic proteins. The helper T−cells secrete
<b><I>growth factors</I></b> (<b>cytokines</b>) that foster the clonal expansion of other
T−cells and/or of antibody-producing cells (the <B>B−lymphocytes</B>). Helper
T−cells are more numerous in youth & maturity, but in the elderly the ratio of
CD8 to CD4 cells increases. CD8 T−cells become more resistant to apoptosis with aging,
whereas CD4 cells become more susceptible to apoptosis.
<p><a href="http://en.wikipedia.org/wiki/Cytomegalovirus" target="_blank">Cytomegalovirus</a>
prevalence significantly increases in the elderly, and may be responsible for much of the
skewed CD8:CD4 ratio of advanced
age [<A HREF="http://www.jimmunol.org/cgi/content/full/176/4/2645"
TARGET="_blank">JOURNAL OF IMMUNOLOGY; Hadrup,SR; 176(4):2645 (2006)</A>].
Cytomegalovirus infection increases with age in
humans [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/17029132"
TARGET="_blank">CLINICAL INFECTIOUS DISEASES; Staras,SAS; 43(9):1143-1151 (2006)</A>],
primarily infects antigen-presenting cells & can increase inflammatory
cytokines [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/19367559"
TARGET="_blank">REVIEWS IN MEDICAL VIROLOGY; Varani,S; 19(3):131-145 (2009)</A>],
and is associated with
immunosenescence [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/19535233"
TARGET="_blank">CURRENT OPINION IN IMMUNOLOGY; Derhovanessian,E; 21(4):440-445 (2009)</A>].
Naive CD4 cells decline rapidly after
age 65 [<A HREF="http://www.jimmunol.org/cgi/content/full/174/11/7446"
TARGET="_blank">JOURNAL OF IMMUNOLOGY; Naylor,K; 174(11):7446-7452 (2005)</A>].
<P>There are two types of helper T−cells, designated <B>T<SUB>H</SUB>1</B> (type 1)
and <B>T<SUB>H</SUB>2</B> (type 2). The T<SUB>H</SUB>1 cells promote growth of
T−lymphocytes with the cytokine <B>InterLeukin−2</B> (<B>IL−2</B>), whereas the
T<SUB>H</SUB>2 cells promote growth of B−lympocytes with the cytokine
<B>InterLeukin−4</B> (<B>IL−4</B>). T<SUB>H</SUB>1 cells are more prominent in
autoimmune infections, whereas T<SUB>H</SUB>2 cells are more prominent in viral infections.
In youth & maturity the T<SUB>H</SUB>1 cells predominate, but in the elderly the
T<SUB>H</SUB>2 cells predominate [MECHANISMS OF AGING AND DEVELOPMENT 94:1-5 (1997)].
Moreover, aging is accompanied by a significant loss of IL−2 as well as of IL−2 receptors
— a phenomenon thought to be responsible for the significant decline of <B>proliferation</B>
(clonal expansion) in response to antigens seen with aging [SCIENCE 273:70-74 (1996)].
The decline of T−cell activation due to reduced IL−2 production is at least partially due to
oxidation-damaged proteasomes being less capable of inducing the gene transcription factor
NFκB [CELLULAR IMMUNOLOGY 192:167-174 (1999)].
<P>Proliferation of T−cells in response to antigenic or mitogenic (cell-division stimulating)
signals also declines with aging — apparently due to to decline in activity of the <B>M</B>itogen
<B>A</B>ctivating <B>P</B>rotein <B>K</B>inase (<B>MAPK</B>) cascade which causes cell surface
signals to alter gene expression. CRAN (<A HREF="../calories/calories.html"
TARGET="_blank">Caloric Restriction with Adequate Nutrition</A>) significantly reduces the
decline of MAPK activity associated with aging [PROCEEDINGS OF THE SOCIETY FOR
EXPERIMENTAL BIOLOGY AND MEDICINE 223:163-169 (2000)]. But
<a href="../nutrceut/Selenium.html" target="_blank">selenium supplementation</a> has been shown
to restore lymphocyte proliferation in aged mice to that of normal young adults [PROCEEDINGS OF
THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE; Roy,M; 209(4):369-375 (1995)].
<P>The combination of low T−cell proliferation and low CD4/CD8 ratio was highly predictive of low
2−year survival in a study of people in the 86−92 age range [JOURNALS OF GERONTOLOGY
50A(6):B378-B382 (1995)]. <a href="../nutrceut/Melatonin.html" target="_blank">Melatonin</a> elevates
the CD4/CD8 ratio [<A HREF="http://www.immunityageing.com/content/2/1/17"
TARGET="_blank">IMMUNITY & AGEING; Srinivasan,V; 2:17 (2005)</A>]. Immune function is very
important for the elderly because
infection causes an increasing percentage of deaths for those over 80 years of
age [JOURNALS OF GERONTOLOGY 52A(1):B67-B77 (1997)] and AMERICAN JOURNAL OF
MEDICINE; 114:365-369 (2003)].
<p><a href="http://en.wikipedia.org/wiki/Regulatory_T_cell" target="_blank">Regulatory T−cells</a>
that suppress T−cell-mediated autoimmune diseases in humans decline with
age [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/14515359"
TARGET="_blank">JOURNAL OF NEUROSCIENCE RESEARCH; Tsaknaridis,L;
74(2):296-308 (2003)</A>].
<P><B>Natural Killer</B> (<B>NK</B>) cells differ from cytotoxic T−cells by the ability
to lyze pathogenic cells without the need of antigens. NK cells decline in activity
with age, but this decline is compensated for by an increase in NK cell numbers. In
centenarians, however, no decline in NK activity has been seen — nor was there a decline
in youthful CD8/CD4 cells [IMMUNOLOGY TODAY; Franceschi,C; 16(1):12-16 (1995)].
<P><B>B−cells</B> from older animals produce less antibody and express less of the surface
CD40 protein which causes B−cell activation and differentiation. The decline in T−cell
activity with age is responsible for most of the decline in B−cell numbers and activity.
<P><B>Macrophages</B> are immune-system cells that "eat" foreign
particles (including bacteria) and digest the particles in lysosomes. <B>Monocytes</B>
are the small blood stream cells that swell to become macrophages after migrating into
tissues. Monocytes from elderly humans have a greatly reduced capacity to produce the
cytokine <B>InterLeukin−1</B> (<B>IL−1</B>) and the toxic free radicals that
macrophages use to kill foreign or cancerous cells [THE JOURNAL OF IMMUNOLOGY
154:832-843 (1995)]. Nonetheless, the superoxide, hydrogen peroxide, hydroxyl ions &
nitric oxide produced by neutrophils & macrophages to kill bacteria can attack native
tissues in age-associated chronic inflammation. The reactive products of nitric oxide
and oxygen species inhibit PARP-mediated DNA repair [FREE RADICAL BIOLOGY &
MEDICINE 35(11):1431-1438 (2003)].
<P> Some of the decline in immune function in the elderly may be due to protein
cross-linking in tissues & blood vessels reducing immune-cell mobility and
access to infected areas. Poor nutrition in the elderly is also a factor.
Supplements consisting of recommended dietary allowances of nutrients
(plus extra Vitamin E & beta-carotene) significantly improved the
immune status of elderly subjects [THE LANCET 340:1124-1127 (1992)].
Supplementation with the steroid hormone <A HREF="../nutrceut/DHEA.html" TARGET="_blank">
<B>D</B>e<B>H</B>ydro<B>E</B>pi<B>A</B>ndrosterone</A> (<B>DHEA</B>, a hormone
that dramatically declines with age) increased IL−2 & Interferon-gamma
activity in mice [THE JOURNAL OF INFECTIOUS DISEASES 167:830-840 (1993)].
<p>Vulnerability to death by influenza & pneumonia increases rapidly with age in the United
States. A person aged 50−64 is nearly ten times more likely to die from an influenza-associated
death as a person in the 5−49 age group. And a person over 65 is over ten times more likely
to die from an influenza-associated death as a person in the 50−64 age group. A person over
85 is about 16 times more likely to die an influenza-associated death as a person in the 65−69
age group [<A HREF="http://jama.ama-assn.org/cgi/content/full/289/2/179"
TARGET="_blank">JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION; Thompson,WW; 289(2):179-186 (2003)</A>].
Vaccination of the elderly reduces influenza-associated death by
50% [<A HREF="http://archinte.ama-assn.org/cgi/content/full/165/3/274"
TARGET="_blank">ARCHIVES OF INTERNAL MEDICINE; Hak,E; 165(3):274-280 (2005)</A>].
<P><a href="#contents"> (return to contents)</a>
<H3><a name="inflame">XX. INFLAMMATION AND AGING </a></H3>
<P>With aging the body contains increasing quantities of
<A HREF="../health/MacroNut.html#mechanisms" TARGET="_blank">proinflammatory
cytokines</A> such as TNF−α, IL−1 and IL−6, which
is positively associated with cardiovascular disease
mortality [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/12645876"
TARGET="_blank">IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA; Bruunsgaard,H;
23(1):15-39 (2003)</A>]. The increase in memory cells results in an increase in
the cytokines IL−4 & IL−10 that are produced by the memory cells.
Lifetime exposure to infectious disease reduces lifespan
by accelerated immunosenescence [FEBS LETTERS; Martinis,MD; 579:2035-2039 (2005)] and
chronic inflammation [SCIENCE; Finch,CE; 305:1736-1739 (2004)]. Chronic inflammation
is implicated in atherosclerosis, arthritis, <A HREF="../lifeext/Alzheimer.html"
TARGET="_blank">Alzheimer's Disease</A>, <A HREF="../health/cancer.html"
TARGET="_blank">cancer</A>, <A HREF="../MacroNut.html#syndrome"
TARGET="_blank">the metabolic syndrome (type 2 diabetes)</A> and numerous other
afflictions affecting the elderly. Inflammation is probably not the major cause of
the damage & degeneration of aging, but it contributes to the damage. Free radicals
and oxidized glycation products (AGEs) are contributers to chronic inflammation.
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>Effects of Aging and Calorie Restriction (CR)</B></CAPTION>
<TR><TD WIDTH="350">
<img src="Age_NFkB.jpg" width="350" height="125" alt="Aging and Calorie Restriction (CR) Effects">
</TR></TD>
<CAPTION ALIGN=BOTTOM><B>GC=GlucoCorticoids</B></CAPTION>
</TABLE>
<p>Aging is associated with increasing activity of the
<A HREF="../health/cancer.html#inflame" TARGET="_blank">pro-inflammatory transcription factor
NF-κB</A> (<B>NF−κB</B>).
NF−κB is normally bound to <B>IκB</B> protein in the cytoplasm,
but is released to enter the nucleus when infection, oxidative stress or pro-inflammatory
cytokines cause <A HREF="#protein" TARGET="_blank">ubiquitination
and subsequent protease degradation</A> of IκB. NF−κB increases transcription of genes
coding for TNF−α and IL−1, which can result in a positive feedback loop. The
ability of free radicals (<b>ROS</b>, Reactive Oxygen Species) to cause NF−κB release
and the production of ROS by inflammation also results in a positive feedback loop.
NF−κB and TNF−α are central to the aging-associated increase
in chronic inflammation. Although glucocorticoids are increased in aging & CRAN and can
inhibit NF−κB, stimulation of NF−κB by stressors predominates. Not
only does NF−κB release increase with age, but aging results in NF−κB binding more
strongly to DNA [<A HREF="http://www.biochemj.org/bj/318/0603/bj3180603.htm"
TARGET="_blank">BIOCHEMICAL JOURNAL; Helenius,M; 318(Pt 2):603-608 (1996)</A>].
Age-associated increases in <a href="http://en.wikipedia.org/wiki/Ceramide"
target="_blank">ceramide</a> results in increased NF−κB
activation [<A HREF="http://www.jimmunol.org/cgi/content/full/179/7/4829"
TARGET="_blank">THE JOURNAL OF IMMUNOLOGY; Wu,D; 179(7):4829-4839 (2007)</A>].
<p>NF−κB induced chronic inflammation in combination with its ability to
suppress apoptosis (inhibiting the elimination of cancer cells) often leads to
cancer [NATURE IMMUNOLOGY; Karin,M; 3(3):221-227 (2002)]. Cancer can also be
initiated by NF−κB induction of inducible Nitric Oxide Synthetase (<B>iNOS</B>),
leading to DNA damage, and the inhibition of apoptosis by NF−κB again
favors cancer [NATURE REVIEWS, IMMUNOLOGY; Karin,M; 5:749-759 (2005)].
<P><TABLE BORDER = "2" ALIGN=RIGHT>
<CAPTION ALIGN=TOP><B>TNF−α products</B></CAPTION>
<TR><TD WIDTH="300">
<img src="TNF_CRP.jpg" width="300" height="250" alt="TNF−α products">
</TR></TD>
</TABLE>
<p>Aside from the induction of <b>TNF−α</b> (Tumor Necrosis Factor-alpha) by
NF−κB, <a href="../health/MacroNut.html#mechanisms"
target="_blank">TNF−α is produced by visceral fat</a>. Obese people can
produce twice as much TNF−α as lean people produce.
White adipose tissue attracts macrophages, which produces
the inflammatory agents (like TNF−α) associated with obesity-induced insulin
resistance [<A HREF="http://www.jci.org/articles/view/19451"
TARGET="_blank">JOURNAL OF CLINICAL INVESTIGATION; Xu,H; 112(12):1821-1830 (2003)</A>].
Surgical removal of visceral fat (but not subcutaneous fat) extends the mean
and maximum lifespan of rats [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/19364483"
TARGET="_blank"> BIOCHEMICA ET BIOPHYSICA ACTA; Huffman,DM; 1790(10):1117-1123 (2009)</A>].
TNF−α can induce apoptosis, but only if protein synthesis is
inhibited [SCIENCE; Beg,AA; 274:782-784 (1996)].
<p>TNF−α upregulates NF−κB and <b>IL−6</b> (InterLeukin−6).
IL−6 upregulates pro-inflammatory cytokine <b>IL−1</b> and induces the liver to produce
the inflammatory protein <b>CRP</b> (C−Reactive Protein). Proinflammatory cytokines
have been shown to induce cellular senescence [FREE RADICAL RESEARCH; Sasaki,M;
42(7):625-632 (2008) and CELL; Kuilman,T; 133(6):1019-1031 (2008)]. But IL−6
but also induces production of the anti-inflammatory cytokine <b>IL−10</b> while
inhibiting TNF−α. IL−10 (which inhibits TNF−α production)
is produced in larger quantities when exogenous S-adenosylmethionine is
administered [<A HREF="http://ajpgi.physiology.org/cgi/content/full/284/6/G949"
TARGET="_blank">AMERICAN JOURNAL OF PHYSIOLOGY; Song,Z; 284(6):G949-G955 (2003)</A>].
CRP is an important risk factor for myocardial infarction
(heart attack). A four-year study of women showed those in the highest quarter of
blood CRP had 15.7 times greater risk of developing type 2 diabetes as those in
the lowest quarter [JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION; Pradham,AD;
286(3):327-334 (2001)]. In a study of men, those in the highest quarter of blood CRP
had 3 times the risk of developing dementia as those in the lowest quarter [ANNALS
OF NEUROLOGY; Schmidt,R; 52(2):168-174 (2002)].
<p>Increasing plasma levels of pro-inflammatory cytokines with aging can induce
a stress response that is responsible for the increased plasma levels of cortisol
associated with aging [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/19109735"
TARGET="_blank">INFLAMMATION RESEARCH; Sergio,G; 57(12):558-563 (2008)</A>].
Although elevated cortisol is generally anti-inflammatory in the periphery,
cortisol can be pro-inflammatory in the hippocampus and cerebral
cortex [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1997278/"
TARGET="_blank">BRAIN, BEHAVIOR, AND IMMUNITY; Sorrells,SF; 21(3):259-292 (2007)</A>].
<p>Exercise can be very anti-inflammatory by increasing muscle-derived IL−6
production (which is independent of TNF−α) and reducing
CRP [<A HREF="http://jap.physiology.org/cgi/content/full/98/4/1154"
TARGET="_blank">JOURNAL OF APPLIED PHYSIOLOGY; Peterson,AWW; 98(4):1154-1162 (2005)</A>].
Adequate <a href="../health/sleep.html" target="_blank">sleep</a>
can reduce TNF−α and IL−6 secretion (both of which
induce sleepiness & fatigue). Reduction of IL−6 production by the
administration of sex steroids has been suggested as a means of reducing problems
with sleepiness & fatigue in the
elderly [<A HREF="http://jcem.endojournals.org/cgi/content/full/88/5/2087"
TARGET="_blank">THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM;
Vgontias,AN; 88(5):2087-2095 (2003)</A>]. DHEA can also reduce
IL−6
production [<A HREF="http://jcem.endojournals.org/cgi/content/full/83/6/2012"
TARGET="_blank">THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM;
Straub,RH;83(6):2012-2017 (1998)</A>].
<p>CycloOXygenase (COX) enzyme activity increases with age, thereby increasing the
production of prostaglandins that inhibit T−cell proliferation. Increased levels
of hydrogen peroxide probably are responsible for the age-related increase in COX
activity, indicated by the fact that <a href="../nutrceut/VitaminE.html"
target="_blank">Vitamin E</a> attenuates COX activity and restores T−cell
proliferation [<A HREF="http://ajpendo.physiology.org/cgi/content/full/275/3/C661"
TARGET="_blank">AMERICIAN JOURNAL OF PHYSIOLOGY; Wu,D;
275(3 Pt 1):C661-C668 (1998)</A>].
<p><a href="../health/MacroNut.html#AGEs" target="_blank">Advanced Glycation
End-products (AGES)</a> not only originate from metabolism,
but can be ingested in diet or tobacco smoke and contribute significantly to
inflammation. AGEs can activate
NF−κB [<A HREF="http://www.pnas.org/cgi/content/full/99/24/15596"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Vlassara,H;
99(24):15596-15601 (2002)</A>]. High blood insulin potentiates NF−κB
in a dose-dependent
manner [<A HREF="http://circres.ahajournals.org/cgi/content/full/87/9/746"
TARGET="_blank">CIRCULATION RESEARCH; Golovchenko,I;87(9):746-752 (2000)</A>].
Increased NF−κB activity by AGEs is often mediated by a Receptor
for AGE (<b>RAGE</b>), which can also be activated by
TNF−α [<A HREF="http://www.jbc.org/cgi/content/full/275/33/25781"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Tanaka,N; 275(33):25781-25790
(2000)</A>]. NF−κB activated by oxidative stress or AGEs upregulates the expression
of RAGE (more AGE receptors), creating a positive feedback loop that worsens chronic
inflammation [<A HREF="http://circres.ahajournals.org/cgi/content/full/84/5/489"
TARGET="_blank">CIRCULATION RESEARCH; Schmidt,AM; 84(5):489-497 (1999)</A>].
<p>Even though age-associated chronic diseases are important components of
<a href="#progeria" target="_blank">segmental progerias </a>, they are often
dissociated from aging <i>per se</i> because those people who achieve
maximum lifespan typically do not die of these diseases. The role of controllable
risk factors like obesity, exercise, AGE ingestion and Vitamin E supplementation
would also tend to dissociate inflammation and chronic disease from a central
role in the essential aging process. Nonetheless, these chronics diseases
<b><i>are</i></b> aging-associated and it is likely that inflammation plays
some role in the degenerative & damaging processes known as aging.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="toxins">XXI. ACCUMULATION OF TOXINS AND CHEMICAL GARBAGE </a></H3>
<P> Many chemicals accumulate in the cells with age, including toxic
& inert substances from the exterior and similar substances arising as
byproducts of cellular metabolism [notably Advanced Glycation End-products (AGEs) and
lipid peroxidation debris]. Fat-soluble substances (such as DDT &
PCBs) are particularly slow to be eliminated. Iron tends to accumulate in cell nuclei
with aging, as does aluminum. Aluminum transforms metabolically active DNA
into an inert state. Lead also accumulates in cells, and is neurotoxic.
Cytochrome P−450 detoxification enzymes of the liver (which have maximal
light absorption at 450 nanometer wavelength) decline with age. In the 1976 to
1980 period, the 15% of US population with the highest blood levels of
lead had 49% higher cardiovascular mortality and 68% higher
cancer mortality [<A HREF="http://archinte.ama-assn.org/cgi/content/full/162/21/2443"
TARGET="_blank">ARCHIVES OF INTERNAL MEDICINE; Lustberg,M; 162(21):2443-2449 (2002)</A>].
<P> Non-dividing cells (muscle cells, heart muscle cells and neurons) are
not susceptible to the Hayflick Limit. Nor is double-chromosome damage of as
great concern in non-dividing cells as it is for dividing cells. But for
non-dividing cells that cannot be replaced — heart muscle cells and neurons —
the accumulation of cellular garbage may be a very significant factor in
cellular aging. Species survival may be thus dependent on the creation of new
organisms once the old ones have accumulated too much chemical garbage to
be functional.
<P> Of particular note is <B>lipofuscin</B> (age pigment), which can
accumulate in large quantities in non-dividing cells. Lipofuscin is regarded as a
product of <B>lysosomes</B> — organelles containing hydrolytic enzymes
to degrade proteins, lipids and damaged organelles. As production of
lysosome enzymes decline with age — and as lysosomes engulf increasingly
cross-linked proteins & lipids that are resistant to enzyme
degradation — dysfunctional lysosomes (bloated with indigestible contents)
accumulate in cells containing <B>lipofuscin granules</B>. Lipofuscin granules
(engorged lysosomes) are
characterized by a single membrane envelope, enclosing yellowish-brown
material that can autofluorescence.
<P>Inhibitors of <B>proteases</B> (enzymes that degrade protein) and Vitamin E
deficiency result in lipofuscin-like cellular residues — a clue to
the origin of lipofuscin. There is evidence that lipofuscin formation
inhibits protein degradation, thereby creating a vicious cycle that
promotes its own formation [EXPERIMENTAL GERONTOLOGY 36:475-486
(2001)]. In contrast to ceroids — which rapidly accumulate extra− & intra−
cellularly in pathologic conditions — lipofuscin accumulates slowly, universally and
specifically accumulates in lysosomes [ANNALS OF THE NEW YORK ACADEMY OF SCIENCES; Portas,EA;
959:57-65 (2002)]. The composition of lipofuscin — nearly half protein, one-third
carbohydrate and the rest lipid — indicates that it is primarily composed of AGEs rather
than lipid peroxidation products [BIOCHEMICAL AND BIOPHYSICAL RESEARCH
COMMUNICATIONS 236:327-332 (1997)].
<P> Lipofuscin is normally diluted-out of dividing cells, although it is seen
in increasing amount in fibroblasts nearing the Hayflick Limit. Lipofuscin
accumulation in the non-dividing cells of the brain&heart is very
prominent and is, in fact, regarded as a biomarker of aging. Lipofuscin
accumulation in retinal pigment epithelial cells may lead to age-related
macular degeneration, the leading cause of blindness in the developed world.
The fact that lipofuscin accumulates at a higher than normal rate in
<A HREF="../lifeext/Alzheimer.html" TARGET="_blank">Alzheimer's Disease</A>
and the fact that the disease is also characterized by abnormal
tau-protein and amyloid-protein suggests that creation of defective protein
and/or problems with removal of defective protein could be the underlying
cause of Alzheimer's Disease.
<P>Aging due to free-radicals & glycation of macromolecules other than DNA would be
expected more in non-dividing cells than dividing cells — most notably in neurons. That
lipofuscin is a component of neuron aging due to free-radical damage is indicated by the
high levels of metals (especially iron) in lipofuscin. Oxidative stress has been shown to
promote lipofuscin formation, whereas antioxidants reduce lipofuscin formation [FREE
RADICAL BIOLOGY & MEDICINE 33(5):611-619 (2002)]. Although antioxidants cannot extend
maximum lifespan of organisms as a whole, they may extend the maximum lifespan of neurons
or even the entire brain. If so, antioxidants combined with organ replacement could be
a means of extending maximum lifespan.
<P>Lysosomes are normally responsible for degradation of aging mitochondria. But as
lysosomes become increasingly dysfunctional due to accumulation of indigestible lipofuscin,
cells become increasingly populated with aging, swollen mitochondria that produce less
energy and more superoxide. Reactive oxygen species produce more aldehydes and more
aldehyde-bridges between proteins, resulting in more
lipofuscin [<A HREF="http://content.febsjournal.org/cgi/content/full/269/8/1996"
TARGET="_blank">EUROPEAN JOURNAL OF BIOCHEMISTRY 269(8):1996-2002 (2002)</A>]. There
is thus a positive feedback loop of lipofuscin production, impaired lysosomes,
dysfunctional mitochondria and aldehyde formation.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="cancer">XXII. CANCER AND AGING </a></H3>
<P> As a cause of death the relative incidence of cancer increases exponentially
to age 65 and decreases thereafter. At age 65, 30% of North
American deaths are due to cancer, whereas at age 80 only 12% of
deaths are due to cancer — mostly because the relative increase
of cardiovascular and <A HREF="../lifeext/Alzheimer.html"
TARGET="_blank">Alzheimer's Disease</A> is faster than the increase
in cancer with age. Nonetheless aging is a major risk factor for
cancer, and aging is associated with cancer.
<P>But aging can also be distinguished from cancer, much as with other
diseases associated with aging such as atherosclerosis, Alzheimer's Disease,
osteoporosis and arthritis. In children, cancers are predominantly leukemias, lymphomas
and sarcomas, whereas 80% of adult cancers in the United States are carcinomas.
Nearly 90% of mice die of cancer, with about 2/5 of those cancers being lymphomas
in males and about 3/5 lymphomas in females. About 30% of male mouse cancers are
carcinomas and about 40% are sarcomas [RADIATION RESEARCH; Tanaka,IB;
167(4):417-437 (2007)]. In Werner's Syndrome sarcomas (connective tissue
malignancies, usually) are more common than carcinomas. As with the mouse, this may
be due to cellular immortalization by ALT rather than telomerase. These patterns do not
indicate a simple relationship between aging and cancer.
<P>That there is a distinction between aging and
cancer is suggested by the fact that ionizing radiation increases cancer rate,
but has less (if any) effect on the rate of aging. Atomic bomb
survivors [RADIATION RESEARCH; Preston,DL; 160(4):381-407 (2003) and
populations living near a nuclear test site [RADIATION RESEARCH;
Bauer,S; 164(4 Pt 1):409-419 (2005)] showed increased noncancer
mortality from aging-associated diseases (stroke, heart disease, respiratory
disease), but there is no proof that this constituted accelerated aging.
Experimental animals subjected to chronic sublethal
<A HREF="http://www.health.gov.au:80/hfs/arpansa/is_rad.htm" TARGET="_blank">
ionizing radiation</A> (alpha−, beta−, gamma− & X−rays that cause
atoms & molecules to form ions) have shown generalize atrophy
("premature aging") and shortened lifespans,
but single X−ray & ionizing radiation exposures have more noticeably
increased kidney degeneration and cancer (especially leukemia). Other mutagens
increase the risk of tumor-formation without reducing maximum lifespan. These results
indicate that spontaneous mutations & chromosome breakage are not normal contributors
to aging. Mutations due to ionizing radiation are qualitatively different from those
occurring "spontaneously" with the passage of time [MUTATION RESEARCH
375:37-52 (1997)]. Mammals with longer lifespans have been shown to have more
efficient DNA repair of gamma-radiation [EXPERIMENTAL GERONTOLOGY
37:1203-1205 (2002)]. Nonetheless, the view that ionizing radiation causes
accelerated aging is not easily
dismissed [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815743/"
TARGET="_blank">AGING; Richardson,RB; 1(11):887-902 (2009)</A>].
<P>Cancer is a disease of DNA, whereas aging is a disease of all organs, tissues,
cells and macromolecules. Most cancers are caused by chemical carcinogens, which may
result in DNA damage different from DNA damage associated with aging.
Cancer is a disease of dividing cells — especially the
rapidly dividing cells of the epithelium & blood-forming tissues. Non-dividing cells
like neurons or muscle cells don't become cancerous, but aging affects all tissues.
A study of 15 rodent species showed that telomerase repression is a feature of
large size rather than long life, suggesting that tumor initiation usually occurs
during growth and
development [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693359/
TARGET="_blank">AGING CELL; Seluanov,A; 6(1):45-52 (2007)</A>]. Telomerase repression
rather than replicative senescence can be the primary anti-cancer mechanism.
<P>DNA must ultimately be responsible for the great variation of maximum lifespan
between species. But in this respect DNA (the genome) partly is responsible for the production
of reactive oxygen species as well as for the capacity of tissues to withstand oxidative
stress & glycation as well as other chemical challenges. If aging is distinguished
from cancer by toxin/garbage accumulation and by damage to all macromolecules rather
than just DNA, it is nonetheless true that the DNA damage associated with cancer is
at least a <B><I>component</I></B> of aging. This view is supported by the apparent
correlation between maximum lifespan and DNA repair capability seen in species comparisons
— as well as by the signs of accelerated aging seen in many DNA repair diseases.
<P>Clues about the molecular mechanisms of aging & cancer in general could be gained
by comparative analysis of the mechanisms of segmental progerias leading to specific cancers
& specific manifestations of aging. XP, AT & Werner's Syndrome are segmental
progerias due to defective NER, defective cell cycle control & defective recombination
(respectively) leading to high rates of skin cancer, leukemia & sarcomas (respectively).
The cancer symptoms are more prominent with XP & AT, whereas the progeria is more
prominent with Werner's Syndrome. Down's Syndrome & Hutchinson-Gilford Syndrome are
segmental progerias not particularly associated with high cancer risk. Defective DNA
mismatch repair leads to a form of colon cancer (HNPCC) without symptoms of accelerated
aging.
<P>What is the relative contribution of reduced vulnerability to cancer due to reduced
Insulin-like Growth Factor−1 (IGF−1) to the extended lifespan of dwarf mice and to what
extent or by what mechanism is the rate of aging slowed?
<P> Dietary factors, smoking and environmental chemicals can play a significant
role in the incidence of cancer, as indicated by the fact that breast
cancer in North American women is ten times more common than for women
in Japan. And dietary antioxidants — if not supplemental — appear to reduce
the risk of cancer. Environmental factors associated with aging
or maximum lifespan might cause increased glycation, generalized macromolecule damage
and lipofuscin accumulation along with DNA damage.
<P> But in the absence of other diseases, there is a general
and exponential increase in the likelihood of contracting cancer
as a subject (human or other mammal) ages. There is an increased
cumulative effect of DNA mutation and a decline in immune-system
function with age. Nonetheless, the pattern of cancer increase associated with
aging is very different from immune deficiency disease. Whales have 600 times
as many cells as humans yet suffer no greater incidence of cancer. It is
improbable that whales have an immune system that is 600 times better than
that of humans. Whales must have other special defenses against cancer (which would
be well worth learning to understand). The high rate of cancer in rodents is not
surprising in light of the proclivity to immortalization associated with their
telomeres. But the capacity of mammalian species to detoxify the
<A HREF="../health/cancer.html#chemicals" TARGET="_blank">carcinogenic chemical</A>
benzo(a)pyrene to a water-soluble form also correlates well with maximum
lifespan [EXPERIMENTAL CELL RESEARCH 116:359-364 (1978)].
<P>DNA damage due to mutagens more readily leads
to cancer, but defective DNA repair more readily leads to aging. Nearly all of the
"accelerated aging" diseases involve defective DNA repair. Better DNA
repair allows the deer mouse to live much longer than the house mouse. It may be
that mutagens damage both DNA as well as cellular defenses against DNA damage,
but that when DNA repair is defective cells can respond by inducing cellular
senescence or apoptosis — preventing cancer, but accelerating aging. With aging the
declining efficiency of cellular mechanisms means that there is a decreasing
likelihood that cancerous cells will be eliminated by apoptosis.
<P> For technical details about the nature of cancer (and
methods of prevention) — see my essay
<A HREF="../health/cancer.html" TARGET="_blank">Cancer Death</A>.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="biomarkers">XXIII. BIOMARKERS OF AGING </a></H3>
<P> Individuals of different species seem to age at different rates for different reasons.
Laboratory studies of lifespan is currently only feasible for short-lived species, but if
some <B>biomarker</B> could be found for determining <B>biological age</B> (rather than
<B>chronological</B> age) then human lifespan studies would be feasible. A biomarker of
aging would be a better predictor of life expectancy and future functionality than
chronological age. Unfortunately,
we even lack a method for biomarker validation. And if a biomarker could be validated
for rodents, how could we prove that the biomarker applied equally-well to humans? Without
biomarkers of aging we cannot say definitively if "accelerated aging" diseases
exist.
<P> Without validated biomarkers of aging, it is difficult to prove that nutrients, drugs
or other interventions are slowing aging and extending the maximum lifespans of humans.
With biomarkers, it would only be necessary to show reduced deterioration within a
reasonable time-frame (a few years) in humans. Without biomarkers, positive proof of an
anti-aging intervention for humans could only come by observing effects on lifespan in
studies lasting decades or centuries. To be of use within our own lifetimes, the results
from short-lived mammals may be the best we can hope for if biomarkers are not found.
Despite years of effort, biogerontologists have not had much success in their search
for biomarkers of aging [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/17071038"
TARGET="_blank">EXPERIMENTAL GERONTOLOGY; Johnson,TE; 41(12):1243-1246 (2006)</A>
and <A HREF="http://www.reference-global.com/doi/abs/10.1515/BC.2008.034"
TARGET="_blank">BIOLOGICAL CHEMISTRY; Simm,A; 389(3):257-265 (2008)</A>].
<P>Insofar as <A HREF="../calories/calories.html" TARGET="_blank">Caloric Restriction with
Adequate Nutrition</A> (CRAN) seems to slow aging in rodents and many other short-lived
species, long-term studies of CRAN on monkeys are being conducted to establish if CRAN also
slows aging in primates. Although it will take decades for these studies to run to
completion and current data is not yet statistically significant, rhesus monkeys on CRAN
show the same reductions of body temperature & plasma insulin as CRAN rodents, as well
as showing a slower decline in serum
<A HREF="../nutrceut/DHEA.html" TARGET="_blank">DeHydroEpiAndrosterone Sulfate</A>
(<B>DHEAS</B>). Men with
greater survival in the Baltimore Longitudinal Study of Aging also show reduced body
temperature & plasma insulin, along with elevated serum DHEAS — suggesting that
these three factors may be biomarkers of biological age [SCIENCE 297:811 (2002)].
<P>Skin biopsies from CRAN & control nonhuman primates have been used to assess
glycation & <B>glycoxidation</B> (oxidation of glycation products to form AGEs).
<B>Furosine</B> as a measure of glycation increased mildly with age in the control
animals and this increase was significantly reduced in CRAN animals. Using
<a href="http://en.wikipedia.org/wiki/Pentosidine"
target="_blank">pentosidine</a> as a measure of glycoxidation, no significant variations were
observed — but results for tissues other than skin might have been different [JOURNALS
OF GERONOTOLOGY 58A(6):508-516 (2003)].
<P>F<SUB>2</SUB>−isoprostanes are stable products of oxidized arachidonic acid
which can be readily measured in urine to quantify lipid peroxidation. Plasma
concentrations rise dramatically with age in rats, providing support for the
association of lipid peroxidation with aging and for the potential of F<SUB>2</SUB>−isoprostanes
as biomarkers of aging [BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
287:254-256 (2001)]. (For details on isoprostanes see
<A HREF="../health/essfat.html#cell" TARGET="_blank">Essential Fatty Acids in Cell
Membranes</A>.)
<P>A statistically significant trend (with extremely wide variation) of T−cell subsets in
mice provides a potential biomarker. Mice with low levels of CD4 & CD8 memory cells, high
levels of CD4 naive cells and low levels of P−glycoprotein CD4 cells live 6%
longer [JOURNALS OF GERONTOLOGY; Miller,RA; 56A(4):B180-B186 (2001)]. The "biomarker"
based on these four T−cell subsets was able to predict longevity of 18-month-old mice
with <A HREF="http://www.sportsci.org/resource/stats/pvalues.html" TARGET="_blank">P−values</A>
less than 0.003. Mice most often die of cancer, so this might be a
better indicator of mortality risk. But if valid, would this biomarker indicate that the immune
system theory of aging predominates, or would it indicate that the aging process simply impinges
most predictably on the immune system?
<p>With aging the <a href="../health/sleep.html#eeg" target="_blank">sleeping EEG patterns</a>
known as "sleep spindles" and "K−complexes" diminish in
number — and it has been suggested that this change can be used as a biomarker of
brain aging [CLINICAL NEUROPHYSIOLOGY; Crowley,K; 113(10):1615-1622 (2002)]. There
is also reduced circadian signaling with age, and much of this reduction may be
due to reduced <a href="../nutrceut/melatonin.html" target="_blank">melatonin</a>
secretion [NEUROBIOLOGY OF AGING; Munch,M; 26(9):1307-1319 (2005)].
<P>In the Framingham study (a longitudinal epidemiological study
of large size and long duration in Framingham, Massachusetts that has
focused on cardiovascular disease risk factors) lung volume (largest
volume of air that can be voluntarily expelled from the lung) — which
decreases with age in smokers & non-smokers —
was well correlated with risk of death in the 45−74 year-old age-range.
But even lung volume was inferior to chronological age as a predictor
of overall mortality risk. Forced expiratory volume in one second remains
the best predictor of all-cause
mortality [<A HREF="http://chestjournal.chestpubs.org/content/118/3/656.long"
TARGET="_blank">CHEST; Schunemann,HJ; 118(3):656-664 (2000)</A> and
<A HREF="http://erj.ersjournals.com/cgi/content/full/30/4/616"
TARGET="_blank">EUROPEAN RESPIRATORY JOURNAL; Young,RP; 30(4):616-622 (2007)</A>],
but that does not mean that it is a biomarker of aging.
<P>If mortality risk were the definitive characteristic of aging, then standing in an
open field criss-crossed with machine-gun fire would be a biomarker of aging. If aging
is damage to organs, tissues, cells and macromolecules then many kinds of damage need
to be considered. Certain kinds of damage are more related to specific disease conditions
than generalized "aging". Damage to substantia nitra cells leads to
Parkinson's Disease, nuclear DNA mutations lead to cancer, glycation of lens crystallins
leads to cataracts, etc. Nonetheless, aging increases the predisposition to these
disease conditions.
<P>Partly because of the failures to find biomarkers, some biogerontologists question that
a unitary process of aging exists — asserting that the phenomenon called "aging"
is really multiple degenerative processes operating in parallel. A unitary cause of aging
might necessitate discovery of a unitary biomarker. The multiple forms of damage to
macromolecules, cells and tissues associated with aging points to multiple causes, and
would necessitate multiple biomarkers. Despite the fact that
different mechanisms must be involved, the rather uniform slowing of aging seen for dwarf
mice and CRAN-diet (versus ad-libitum fed) animals would seem to validate the existence of a
unitary aging process — as does the comparison of aging rates between species or breeds
of dogs.
<p>But aging can only be the result of damage to macromolecules: proteins, lipids, carbohydrates,
and DNA (including telomeres). Causes of aging damage are reactive oxygen & nitrogen species,
sugars (glycation), radiation, pathogens, inflammatory cytokines, and accumulated toxins
(metals, PCBs, dioxins, etc.). The different aging rates of different species is due to
the fact that endogenous damage is produced at different rates (eg, bird mitochondria produce
fewer free radicals than mammalian mitochondria), different protective mechanisms exist
(eg, naked mole rats arrest cancer growth with contact inhibition), and more long-lived
species more effectively eliminate damage (eg with better lysosome enzymes, better DNA repair,
better autophagy, etc.). If aging is programmed genetically, it can only be programmed to reduce
damage formation or remove/repair damage better or worse.
<p>Exogenous agents can accelerate forms of aging damage. Diabetes and dietary
Advanced Glycation End-products (<b>AGEs</b>) accelerate protein
cross-linking [<A HREF="http://www.pnas.org/content/94/12/6474.long"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Koschinsky,T;
94(12):6474-6479 (1997)</A>]. Immunosenescence is substantially associated with
cytomegalovirus [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/19535233"
TARGET="_blank">CURRENT OPINION IN LIPIDOLOGY; Derhovanessian,E; 21(4):440-445
(2009)<A>]. White blood cell telomere attrition is accelerated in obesity and insulin
resistance [<A HREF="http://circ.ahajournals.org/cgi/content/full/111/17/2171"
TARGET="_blank">CIRCULATION; Gardner,JP; 111(17):2171-2177 (2005)<A>]. There is
considerable overlap in the histopathology of skin photoaging and skin intrinsic
aging [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/12366692"
TARGET="_blank">EXPERIMENTAL DERMATOLOGY; El-Domyati,M; 11(5):398-405 (2002)<A>].
A high fat meal elevates plasma inflammatory cytokines more than a high carbohydrate
meal [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/11923038"
TARGET="_blank">JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY; Nappo,F; 39(7):1145-1150
(2002)<A>], and plasma inflammatory cytokines are substantially associated with
age-related cataract [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/16386984"
TARGET="_blank">AMERICAN JOURNAL OF OPTHALMOLOGY; Klein,BEK; 141(1):116-122 (2006)<A>].
F<sub>2</sub>−isoprostanes (the best marker of lipid peroxidation) are
substantially elevated in the foam cells of atherosclerotic
plaque [<A HREF="http://www.jci.org/articles/view/119735"
TARGET="_blank">JOURNAL OF CLINICAL INVESTIGATION; Pratico,D; 100(8)2028-2034 (1997)<A>],
and F<sub>2</sub>−isoprostanes in the urine of smokers drops by
more than one third after two weeks of smoking
cessation [<A HREF="http://content.nejm.org/cgi/content/full/332/18/1198"
TARGET="_blank">NEW ENGLAND JOURNAL OF MEDICINE; Morrow,JD; 332(18):1198-1203 (1995)<A>].
<p>Because aging is due to multiple forms of damage, there can be no
singular underlying biological age. Cause of death and impairment of
functionality will be a function of which form of damage is the
greatest — which will vary from person to person. Rather than
engage in a fruitless search for a biological age (biomarker of aging),
biogerontologists should seek assays for every possible form of aging
damage. Damage assays can allow for ranking forms of aging damage,
prioritizing interventions, and monitoring intervention effectiveness.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="cran">XXIV. CALORIC RESTRICTION WITH ADEQUATE NUTRITION (CRAN) </a></H3>
<P><A HREF="../calories/calories.html" TARGET="_blank">Caloric Restriction with
Adequate Nutrition</A> (CRAN) dramatically extends the maximum lifespan of laboratory animals.
Victims of starvation & malnutrition are not experiencing the life-extending
benefits of CRAN — <B><I>adequate nutrition</I></B> (vitamins, minerals, essential
amino acids and essential fatty acids in adequate quantity) is absolutely necessary
for calorie restricted diets to extend lifespan. Because almost every aspect of the
aging process appears to be slowed by CRAN, studying CRAN has become a means of
defining & understanding the aging process itself — including the search for
biomarkers of aging.
<P> Rats, mice and hamsters experience maximum
lifespan extension from a diet which contains 40−60% of the calories (but all
of the required nutrients) which the animals consume when they can eat
as much as they want. Mean lifespan is increased up to 65% and maximum lifespan
is increased up to 50%, when CRAN is begun just before puberty. Except for the puberty
effect, it is as if all animals are allotted a lifetime supply of food — and those
who eat more slowly live longer because it takes longer to consume all the food.
<P> The mechanism by which caloric restriction has such dramatic effects is
unproven, but maturity, thymus shrinkage, DNA-repair decline and tumor
formation is delayed. The experimental animals show more complete oxidation
of fatty acids, with fewer ketones (R'RC=O) in the blood, and cell membranes have less
cholesterol & saturated fatty acids. Collagen cross-linking occurs more
slowly in rats on CRAN which have blood glucose levels reduced about 15%
below controls. Reduction of visceral body fat is associated with reduced
<a href="../health/MacroNut.html#syndrome" target="_blank">insulin resistance</a> due to
reduced levels of proinflammatory cytokines [EUROPEAN JOURNAL OF CLINICAL
INVESTIGATION 32(Suppl 3):24-34 (2002)].
<P>Oxidative damage (8−oxodG) to mtDNA is 16 times greater than to nDNA in the livers of
6−month old rats [<A HREF="http://www.pnas.org/cgi/content/abstract/85/17/6465"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Richter,C;
85(17):6465-6467 (1988)</A>]. Although CRAN does not reduce oxidative damage (8−oxodG) to
rat liver nDNA and only reduces oxidative damage to mouse liver nDNA by 19%, it completely
eliminates mtDNA damage in both the rat &
mouse [<A HREF="http://www.pnas.org/cgi/content/full/98/18/10469"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Hamilton,ML;
98(18):10469-10474 (2001)</A>]. One year of CRAN in rats has been shown to reduce liver
mitochondrial hydrogen peroxide production from Complex I by 47% [FREE RADICAL
BIOLOGY & MEDICINE; Lopez-Torrez,M; 32(9):882-889 (2002)]. For mammalian species, a
negative exponential correlation has been demonstrated between liver mitochondrial hydrogen
peroxide production and maximum lifespan [JOURNAL OF COMPARATIVE PHYSIOLOGY B;
Perez-Campo,R; 168:149-158 (1998)].
<P> Although CRAN animals produce fewer free radicals, their <B>metabolic rate</B>
(oxygen consumption per gram of tissue) is not reduced. The inner mitochondrial membranes
of CRAN animals have a higher saturated/unsaturated fat ratio making them less vulnerable
to proton leak from lipid peroxidation. Both <A HREF="./aging.html#mitochondria"
TARGET="_blank">state 3 & state 4 respiration rates</A>
are greatly reduced in brain, heart & kidney tissue [THE INTERNATIONAL JOURNAL
OF BIOCHEMISTRY & CELL BIOLOGY 34:1340-1354 (2002)]. CRAN rats show 15% less plasma
glucose and 50% less plasma insulin than controls, having the same rate of glucose
utilization per unit mass, meaning that glucose is being more efficiently
utilized [JOURNAL OF GERONTOLOGY; Masoro,EJ; 47(6):B202-B208 (1992)].
<p>Macroautophagy is normally induced during conditions of starvation. CRAN
in the nematode <b><i>C. elegans</i></b> induces macroautophagy, whereas
inhibiting the genes required for macroautophagy inhibits the genes require
for autophagy — and prevents CRAN from extending
lifespan [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242811/"
TARGET="_blank">PLOS GENETICS; Hansen,M; 4(2):e24 (2008)</A>].
<p>A convincing case has been made that CRAN operates by
evolutionarily-conserved mechanisms of nutrient-sensing molecular
pathways (insulin/IGF-1) in yeast, worms, flies, and
mammals [<A HREF="http://www.sciencemag.org/content/328/5976/321.full"
TARGET="_blank">SCIENCE; Fontana,L; 328:321-326 (2010)</A>]. CRAN does not
increase insulin sensitivity or extend the lifespan of Growth-Hormone Receptor
Knock-out mice, suggesting that insulin sensitivity plays a key role
in life extension by
CRAN [<A HREF="http://www.pnas.org/content/103/20/7901.long"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Bonkowski,MS; 103(20):7901-7905 (2006)</A>]. Exercise, however, increases
insulin sensitivity without increasing maximum
lifespan [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829643/"
TARGET="_blank">AGE; Fontana,L; 32(1):97-108 (2010)</A>].
Reduced body size within a species often correlates with longer lifespan
and reduced plasma IGF−1. Great Danes (400 ng/mL plasma
IGF−1) live about 7 years, whereas
Chihuahuas (40 ng/mL plasma IGF−1) can live over 15 years.
Insulin increases IGF-1 activity by lowering serum IGF-binding
protein [<A HREF="http://www.jbc.org/content/266/28/18868.long"
TARGET="_blank">JOURNAL OF BIOLOGICAL CHEMISTRY; Powell,DR;
266(28):18868-18876 (1991)</A>].
<p>Longevity in humans is correlated with a genetic predisposition
to low plasma IGF-1 [<A HREF="http://jcem.endojournals.org/content/88/7/3299.long"
TARGET="_blank">JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM;
Bonafe,M; 88(7):3299-3304 (2003)</A>]. Rodents consistantly show reduced
plasma IGF-1 on CRAN, but for humans plasma IGF-1 is reduced by protein
restriction, not calorie
restriction [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673798/"
TARGET="_blank">AGING CELL; Fontana,L; 7(5):681-687 (2008)</A>].
An ongoing study of rhesus monkeys (which have a maximum lifespan of 40 years)
has shown a 50% reduction in cancer and cardiovascular disease for the animals
subjected to 30% calorie restriction compared to
controls [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812811/"
TARGET="_blank">SCIENCE; Colman,RJ; 325:201-204 (2009)</A>].
But the rhesus monkey studies are still in
progress [<A HREF="http://www.sciencemag.org/content/297/5582/811.long"
TARGET="_blank">SCIENCE; Roth,GS; 297:811 (2002)</A>].
<P>There is reasonable evidence that the benefits of CRAN seen in rodents apply to humans.
Contrary to former reports of a "J−shaped" relationship between body
weight and human mortality, when corrections are made for smoking and underlying
disease the relationship is linear [NEW ENGLAND JOURNAL OF MEDICINE; Manson,JE;
333(11):677-685 (1995)]. Of course, anorexics who are malnourished for micronutrients
are not examples of human CRAN. There may well simply be a continuum between
CRAN and the <a href="../health/MacroNut.html#syndrome"
target="_blank">metabolic syndrome</a>, meaning the benefits of CRAN are
simply a matter of quantity of calories, versus the idea that CRAN is
some qualitatively distinct metabolic state.
<p>Humans who have practiced CRAN for about six years show considerable
reduction in risk factors for atherosclerosis, including reduced
LDL-cholesterol, increased HDL-cholesterol, reduced serum triglycerides,
and reduces systolic and diastolic blood
pressure [<A HREF="http://www.pnas.org/content/101/17/6659.long"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Fontana,L; 101(17):6659-6663 (2004)</A>]. It is also to be expected that
CRAN reductions of inflammatory cytokines and growth factors would result
in reduced cancer in humans, as has been seen in rodents and
monkeys [<A HREF="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829867/"
TARGET="_blank">TRENDS IN PHARMACOLOGICAL SCIENCES; Longo,VD; 31(2):89-98 (2010)</A>].
Elderly human subjects
(60 years average age) restricting calories 30% for 3 months showed
a 20% increase in verbal memory
scores [<A HREF="http://www.pnas.org/content/106/4/1255.long"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Witte,AV;
106(4):1255-1260 (2009)</A>].
<p>Substantial evidence indicates that as much as half of the
life-extension benefits of CRAN are due to restriction of the single amino acid
<a href="http://en.wikipedia.org/wiki/Methionine" target="_blank">methionine</a>.
The lifespan of <b><i>Drosophila</i></b> fruit flies can be extended by reducing
casein or methionine [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/20033028"
TARGET="_blank">NATURE; Flatt,T; 462:989-990 (2009)</A>]. In a study of rats given
20% the dietary methionine of control rats, mean
lifespan increased 42% and maximum lifespan increased
44% [<a href="http://www.fasebj.org/content/8/15/1302.long"
target="_blank">THE FASEB JOURNAL;Richie,JP; 8(15):1302-1307
(1994)</a>]. A study of male rats subjected to methionine restriction,
but no restriction of calories, showed the same decreases in mitochondrial reactive oxygen
species and oxidative damage to DNA as was seen with rats subjected to
CRAN [<A HREF="http://www.fasebj.org/cgi/content/full/20/8/1064"
TARGET="_blank">FASEB JOURNAL; Sanz,A; 20(8):1064-1073 (2006)</A>].
(See <a href="../calories/Meth.html" target="_blank">Life Extension
Benefits of Methionine Restriction</a> for more details.)
<P> Attempts have been made to find a pill that would mimic the effects of CRAN. Using
gene chips it has been found that <a href="http://en.wikipedia.org/wiki/Amygdala"
target="_blank">Metformin</a> results in the same gene expression seen in CRAN. (See
<A HREF="http://www.lef.org/magazine/mag2003/2003_preprint_bio_01.html" TARGET="_blank">
http://www.lef.org/magazine/mag2003/2003_preprint_bio_01.html</A>
and <A HREF="http://www.lef.org/magazine/mag2001/sep2001_report_metformin_01.html" TARGET="_blank">
http://www.lef.org/magazine/mag2001/sep2001_report_metformin_01.html</A>.) But Metformin only
extends mouse lifespan a third as much as CRAN.
<P> For technical details about CRAN — plus an account of my personal
experiences with CRAN — see my essays
<A HREF="../calories/cran95.html" TARGET="_blank">Caloric Restriction with Adequate Nutrition — Overview </A>,
<A HREF="../calories/cran98.html" TARGET="_blank">My Practice of Caloric Restriction with Adequate Nutrition</A>
and <A HREF="../personal/regimen.html">My Current Health Regimen — Exercise, Diet, Supplements</A>.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="methods">XXV. OTHER METHODS TO SLOW AGING</a></H3>
<P>As I stated in the beginning, my primary concern in this essay has been
to elucidate the <B><I>mechanisms</I></B> of aging, rather than
<B><I>methods</I></B> to prevent it. But the <B><I>goal</I></B>
of my understanding is indeed to apply
an understanding of mechanisms to the evaluation of methods. Literature
on methods to extend <B><I>maximum</I></B> lifespan which is strongly
grounded in scientific research is rare. The primary reason for this
scarcity is lack of funding for such research.
<P> In contrast with <B><I>maximum</I></B> lifespan, there is a vast
amount of literature on ways to extend <B><I>mean</I></B> (average)
lifespan through diet & exercise and avoidance of dangers, toxins
& disease. Only 26% of smokers live to age 80, in contrast with
57% of nonsmokers [ADDICTION 97:15-28 (2002)]. A practical
life-extensionist currently has far more to gain by utilizing
information available on extending mean lifespan than by preoccupation
with maximum lifespan. Some misguided life-extensionists have discounted
the use of anti-oxidant supplements because they have only been shown
to be of benefit in extending mean lifespan, not maximum lifespan.
<P> A prime candidate for a biomarker
of aging (which has been a focus of attention in the calorie restriction with
adequate nutrition studies of primates) has been
<a href="../health/MacroNut.html#syndrome" target="_blank">insulin resistance</a>.
Reduced glycation may be achieved by reduction of typical blood glucose
levels. Low fat meals are one means to achieve this because fatty acids
promote insulin resistance — and greater insulin resistance means that
higher blood glucose levels are required to supply cells with the same
amount of glucose (causing more glycation) [THE NEW ENGLAND JOURNAL OF
MEDICINE 342(19):1440-1441 (2000) and DIABETES CARE 20(11):1774-1780 (1997)].
(Insulin resistance is a fundamental cause of adult-onset diabetes.) Also,
increased consumption of soluble fiber (particularly the beta-glucan found
in oat bran & barley) lowers 24−hour plasma glucose & insulin
concentrations. Experiments demonstrating that lysine-glycation predicts early
death in both CRAN & freely-fed rats makes lysine-glycation a very promising
biomarker candidate [FASEB JOURNAL 14:145-156 (2000)]. (For more on these
subjects see
<a href="../health/MacroNut.html#syndrome" target="_blank">the metabolic
syndrome</a>)
<P> Although no substance has
been shown conclusively to extend maximum lifespan in humans, a few studies
indicate that some supplements may extend the lives of laboratory mammals
(mice, rats or guinea pigs, usually). The are quite a few studies indicating
that <A HREF="../lifeext/deprenyl.html" TARGET="_blank">Deprenyl</A>, for example,
has extended the maximum lifespan of a variety of mammals.
There is at least one book (self-published), which is based on a serious
attempt to search the scientific literature for methods to extend
maximum lifespan.
Dr. Thomas Donaldson has reviewed those supplements that appear to extend
the lifespan of mammals in at least one scientific study
in his self-published book A GUIDE TO ANTI-AGING DRUGS. It
would be more accurately titled A GUIDE TO ANTI-AGING SUPPLEMENTS because,
although Procaine, Deanol,
<A HREF="../lifeext/deprenyl.html" TARGET="_blank">Deprenyl</A>,
Levodopa, Phenformin and Phenytoin
deserve to be called drugs, Vitamin E, Pyridoxine, Pantothenate, Melatonin,
Cysteine, Chromium and Coenzyme Q10 do not. Five mechanisms are identified
by which these supplements work:
<P>(1) anti-oxidation
<BR>(2) anti-glycation
<BR>(3) affecting metabolism
<BR>(4) improving the immune system
<BR>(5) acting on the brain.
<p>Dr. Donaldson died early in 2006 and his self-published book
may be difficult to obtain.
<P>Although Hormone Replacement Therapy (HRT) to bring androgens, estrogens and
growth hormone to youthful levels improve cognitive function & muscle tone (among other
benefits) these hormones promote cancer growth and therefore may be dangerous to use until
cancer is preventable & curable. By contrast,
<a href="../nutrceut/DHEA.html" target="_blank">DHEA</a> not only protects against obesity,
diabetes & autoimmune disease, it reduces cancerous tumor-formation [ADVANCES
IN ENZYME REGULATION 26:355-382 (1987)] and can protect against excitotoxic damage in
the hippocampus [<A HREF="http://www.pnas.org/cgi/content/full/95/4/1852"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA) 95(4):1852-1857
(1998)</A>].
<P> The <A HREF="../nutrceut/nutrceut.html"
TARGET="_blank">nutraceuticals section of my website</A> describes a number of supplements
which may extend average, if not maximum, lifespan.
<A HREF="http://www.lef.org/magazine/mag_all.html" TARGET="_blank">Life
Extension Magazine</A> — which is available at no cost online — regularly
publishes articles with many fine citations to research on nutraceuticals
(primarily animal studies) which could potentially be of great benefit in
extending human life.
<P> Cardiovascular function declines and insulin resistance increases
with age for most people. But most of these changes can actually be
attributed to declining physical activity and increasing abdominal
obesity associated with aging — rather than senescence <B><I>per
se</I></B>. Higher HDL-cholesterol, lower triglycerides, lower
insulin-resistance & prevalence of diabetes, good cerebral
perfusion, good glucose metabolism, good
cardiovascular function and good endocrine function of older people
who engage in regular vigorous aerobic exercise are nearly to the
level of that seen in their younger counterparts — in sharp
contrast to their sedentary peers [NEW ENGLAND JOURNAL OF MEDICINE
328:533-537 (993); AMERICAN JOURNAL OF PHYSIOLOGY 268:E484-E490
(1995); JOURNAL OF THE AMERICAN GERIATRIC SOCIETY 38:123-128 (1990)].
Health problems caused by sedentary living are too often blamed on
senescence.
<P> Exercise is well-known to lower blood pressure and otherwise improve
cardiovascular health. And, as has been mentioned, exercise can boost
rejuvenating Growth Hormone (GH) more effectively than injections.
Exercise also normalizes other hormone responses to youthful levels
[JOURNALS OF GERONTOLOGY:BIOLOGICAL SCIENCE 51A(1):B30-B37 (1996)] and
reduces insulin resistance [METABOLISM 44(10):1259-1263 (1995)] while improving immune
function [MECHANISMS OF AGING AND DEVELOPMENT 93:215-222 (1997)].
Although excessively strenuous exercise can generate harmful levels of free
radicals, regular endurance exercise protects against free radicals by increasing
muscle levels of SuperOxide Dismutase (SOD), glutathione peroxidase
and reduced glutathione (GSH) (but has no effect on catalase)
[MEDICINE & SCIENCE IN SPORTS & EXERCISE 31(7):987-997 (1999)].
Vitamin E is particularly protective against exercise-induced
free radicals [AMERICAN JOURNAL OF PHYSIOLOGY 264:R992-R998 (1993)].
Vitamin E has a pro-oxidant potential that can only be prevented
by agents like Vitamin C and CoEnzyme Q10, which eliminate the
<B>alpha-Toc<SUP>.</SUP></B> radical [ARTERIOSCLEROSIS, THROMBOSIS
AND VASCULAR BIOLOGY 16:687-696 (1996)]. (For more on exercise, see
<a href="./longgene.html#exercise" target="_blank">Exercise</a>)
<P> According to the Honolulu Heart Program, the best predictors of "successful
aging" were low blood pressure, low blood sugar, abstinence from tobacco and
not being obese. The Framingham study concluded that
by holding 11 different risk factors (such as blood pressure & serum
cholesterol) at the 30-year-old level, women would live to be 97 and
men would live to age 100. As the above review should indicate, many of
the afflictions of aging (including vascular dementia) are the result of
poor cardiovascular health. Therefore, despite the fact that maximum
lifespan is not extended, the effects of extended youth & extended health
would nonetheless be expected from measures extending average lifespan —
cardiovascular health, in particular. Atherosclerosis not only increases
blood pressure and the risk of death from stroke & heart attack, but
reduces the health & function of all organs (including the brain)
through impaired circulation.
<P> It is difficult to
gain much immediate benefit from insights into molecular mechanisms of
aging, but enormous immediate benefit can be gained from reducing
calorie intake (while maintaining adequate nutrition), avoiding tobacco,
avoiding <A HREF="../health/alcohol.html" TARGET="_blank">alcohol</A>,
exercising, taking supplements, eating low-fat/high-fiber diets, etc.
Epidemiological evidence indicates that adherence to a vegetarian diet for more
than two decades can increase lifespan 3.6 years [AMERICAN JOURNAL
OF CLINICAL NUTRITION 78(Suppl):526S-532S (2003)].
And <A HREF="../cryonics/CryoFAQ.html" TARGET="_blank">cryonics</A> may serve
as "first-aid" to transport us to the time when significant
advances in the elimination of senescence have occurred.
<P> Some geronotologists believe that somatic gene therapy
can accomplish such goals as removing the telomerase gene from somatic cells (to reduce
cancer), migrating mitochondrial DNA into the nucleus and utilizing bird mitochondria genes
to create modified human mitochondria which produce fewer free radicals. With
"adequate funding" these gerontologists believe an ageless
mouse can be created within a decade
(<A HREF="http://www.methuselahmouse.org/" TARGET="_blank">The Methuselah Mouse Prize</A>).
<P> Every year we can add to our lives now increases our chances of
living to the time when technology can eliminate & reverse aging — or
cryonics can induce perfect suspended animation.
<P> This essay is not the place to summarize every practice that can
possibly extend life or delay/avert death. See the pages on this
website dealing with
<A HREF="../health/health.html" TARGET="_blank">Health</A>,
<A HREF="../nutrceut/nutrceut.html" TARGET="_blank">Nutraceuticals</A>,
<A HREF="../lifeext/lifeext.html" TARGET="_blank">Life-Extension</A>,
<A HREF="../calories/calories.html" TARGET="_blank">CRAN</A>,
<A HREF="../cryonics/cryonics.html" TARGET="_blank">Cryonics</A>,
<A HREF="./murder.html" TARGET="_blank"> Death by Murder</A>, and my
<A HREF="./causes.html" TARGET="_blank"> statistical summary of all causes of death </A>.
<P><a href="#contents"> (return to contents)</a>
<H3><a name="rejuvenate">XXVI. REGENERATIVE MEDICINE, STEM CELLS AND REJUVENATION</a></H3>
<P>A healthy lifestyle, <A HREF="../calories/calories.html" TARGET="_blank">CRAN</A>,
and perhaps even supplements can do no more than slow the aging process or
extend mean lifespan. Enduring youth might be attained if aging could be stopped
at a youthful age, but it seems unlikely that the damage to organs, tissues, cells
and molecules known as <B><I>aging</I></B> can be stopped completely. Replacing or repairing
damaged organs, tissues, cells and even molecules seems like a better strategy. These
strategies can restore function to old organisms — can even <B><I>rejuvenate</I></B>.
<P>Replacement of old or defective organs is a regenerative technique which has been
tantalizingly close for decades. Only a small fraction of potential candidates for
heart, kidney or liver transplants are able to benefit, because of low availability
and immune incompatibility. The development of a completely mechanical heart remains
out of reach, but there is hope that <B>ventricular assist devices</B> supporting the
left ventricle could benefit most end-stage heart-disease patients. Pigs have many organs
whose size is compatible for human transplant, but immune compatability and the threat
of viral infection remain obstacles.
<p>Although the liver can mostly regenerate lost tissue, wounds to most
body tissues (including myocardial infarction) result in scar formation
rather than regeneration of functional tissue. Stem cells could allow
for true tissue regeneration. Human
<a href="http://en.wikipedia.org/wiki/Embryonic_stem_cell"
target="_blank">Embryonic Stem Cells</a> (<b>ESC</b>) have the
greatest potential to differentiate into any desired tissue type.
<a href="http://en.wikipedia.org/wiki/Retrovirus" target="_blank">Retrovirus</a>
induction of overexpression of certain proteins can generate
<a href="http://en.wikipedia.org/wiki/Induced_pluripotent_stem_cell"
target="_blank">induced Pluripotent Stem Cells</a> (<b>iPSC</b>)
from fibroblasts. iPSC are nearly as pluripotent as ESCs. But both
ESCs and iPSCs can form
<a href="http://en.wikipedia.org/wiki/Teratoma" target="_blank">teratomas</a>
(benign tumors) and induce antigenic tissue rejection (although iPSCs
are less antigenic than ESCs). Antigenicity can be reduced or eliminated
by regenerating the
<a href="http://en.wikipedia.org/wiki/Thymus" target="_blank">thymus
gland</a> [<A HREF="http://www.ncbi.nlm.nih.gov/pubmed/18480814"
TARGET="_blank">NATURE; Chidgey,AP; 453:330 (2008)</A>], by such
means as androgen
blockage> [<A HREF="http://www.jimmunol.org/cgi/content/full/175/4/2741"
TARGET="_blank">THE JOURNAL OF IMMUNOLOGY; Sutherland,JS; 175(4):2741-2753 (2005)</A>].
When available, adult stem cells from the target tissue of the afflicted
patient are ideal for avoiding an antigenic response. But too often (as in
cases of tissue degeneration) such stem cells are not available. Stem cells
from the
<a href="http://en.wikipedia.org/wiki/Cord_blood" target="_blank">umbilical cord</a>
cryogenically stored at birth have the potential for tissue regeneration
later in life.
<P>Most attempts at genetic repair have traditionally involved the use of a retrovirus
to insert a new gene into a random position on a chromosome. But by attaching
<A HREF="../nutrceut/MiscSupp.html#zinc" TARGET="_blank">zinc fingers</A> (which determine
where transcription factors bind) to endonucleases (which break DNA strands) homologous
recombination can be induced to correct and replace defective (or undesired) DNA
sequence. The first applications of this technology are to isolate stem cells from
the bone marrow of patients having blood disease mutations, to correct those
mutations in lab dishes using zinc finger nucleases and to transplant the stem cells
back into the patients [SCIENCE; 310:1894-1896 (2005)].
<P>Regenerative medicine looks for means to mimic salamanders (which can regrow
severed limbs), newts (which can regrow not only limbs, but intestine, jaw and spine)
and zebrafish (which can regrow a heart) — by replacing the dead scar tissue after
a heart attack with new heart cells.
<P>Regenerative medicine uses three different strategies: (1) implantation
of stem cells from culture into an existing tissue structure (2) implantation of
stem cells into a tissue scaffold that guides restoration or (3) induction of
residual cells of a tissue structure to regenerate the necessary body part. A
salamander can not only regenerate a limb, but can regenerate the lens or retina
of an eye and can regenerate an intestine. For regeneration the salamander tissues
form a <B>blastema</B> by dedifferentiation of mesenchymal cells, and the blastema
functions as a self-organizing system to regenerate the
limb [SCIENCE; 310:1919-1923 (2005)]. <a href="http://en.wikipedia.org/wiki/DNA_microarray"
target="_blank">DNA microarray</a> analysis of salamanders has shown that humoral immune
and local tissue factors control the initial phase of limb regeneration, but nerve-derived
factors later become crucial [<A HREF="http://www.biomedcentral.com/1741-7007/7/1"
TARGET="_blank">BMC BIOLOGY; Monaghan,JR; 7:1-19 (2009)</A>].
<P>The MRL mouse, unlike other mice, can regenerate
damaged heart muscle without scar
formation [<A HREF="http://www.pnas.org/cgi/content/full/98/17/9830"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Leferovich,JM;
98(17):9830-9835 (2001)</A>]. Regenerative medicine would also aim to replace substantia
nigra cells in Parkinson's Disease and regrow a spinal cord after spinal cord injury.
Multipotent adult progenitor cells, such as bone marrow cells, have been shown to be
capable of replacing myocardial tissue destroyed by ischemic heart
disease [<A HREF="http://www.pnas.org/cgi/content/full/98/18/10344"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Orlic,D;
98(18):10344-10349 (2001)</A>].
<p>Senescent cytotoxic T-cells have been removed from the serum of mice by
attachment of iron oxide nanoparticles linked to antibodies and applying
a magnetic field to the serum in an extracorporeal circuit [REJUVENATION
RESEARCH; Rebo,J; 13(2-3):298-300 (2010)].
<P>Injured skeletal muscle has the capacity to regenerate in young mammals, but this
capacity is considerably impaired with aging. Activation & proliferation of muscle
regenerating progenitor cells (satellite cells) is dependent upon signalling from
transmembrane <B>Notch</B> receptors. Notch receptors have several <B>ligands</B>, ie,
extracellular molecules that the receptor requires to function. Upregulation of the
Notch ligand <B>Delta</B> has been shown to be sufficient to restore the regenerative
potential of skeletal muscle in old mice [SCIENCE; Conboy,IM; 302:1575-1577 (2003)],
Caution is advised in upregulating Notch, because overexpression of Notch can lead to
cancer [<A HREF="http://breast-cancer-research.com/content/6/6/R605"
TARGET="_blank">BREAST CANCER RESEARCH; Dontu,G; 6:R605-R615 (2004)</A>]. The blood
plasma of young mice have been reported to restore the regenerative potential of both
muscle and liver cells in old mice [NATURE; Conboy,IM; 433:760-764 (2005)]. High
levels of <B>TGF−ß</B> (Transforming Growth Factor beta) in the blood of old mice
appears to be the problem. Systemic (serum) TGF−ß is
immunosuppressive [<A HREF="http://www.jem.org/cgi/reprint/180/5/1587"
TARGET="_blank">THE JOURNAL OF EXPERIMENTAL MEDICINE; Wahl,SM; 180(5):1587-1590 (1994)</A>]
and aged cells have been shown to produce increased levels of
TGF−ß [IMMUNOLOGY LETTERS; Zhou,D; 36(1):7-12 (1993)]. Muscle regeneration
normally makes use of inflammatory
processes [<A HREF="http://ajpregu.physiology.org/cgi/content/full/288/2/R345"
TARGET="_blank">AMERICAN JOURNAL OF PHYSIOLOGY; Tidball,JG; 288(2):R345-R353 (2005)</A>]
and TGF−ß has been shown to inhibit muscle
regeneration [<A HREF="http://circres.ahajournals.org/cgi/content/full/94/5/617"
TARGET="_blank">CIRCULATION RESEARCH; Zhu,S; 94(5):617-625 (2004)</A>].
<P>Organ transplant or even tissue transplant would not be of much benefit for an
aging brain, which is composed of non-dividing, enduring cells (neurons) whose
continued existence is crucial for the retention of knowledge and identity. In this case,
rejuvenation could be done on a molecular level rather than at the tissue or organ level.
For example, Aubrey de Grey has suggested that genes taken from bacteria could be
transmitted into the genome of human neurons to produce enzymes that dissolve &
eliminate lipofuscin, thereby rejuvenating the neuron. The same gene in blood vessel
"foam cells" could reverse atherosclerosis. There is evidence that the
extracellular protein cross-linking due to glycation which
leads to arterial wall stiffening as well as stiffening of the left ventricle can be
reversed by the thiazolium derivative ALT−711, which catalytically breaks
cross-links [<A HREF="http://www.pnas.org/cgi/content/full/97/6/2809"
TARGET="_blank">PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA)
97(6):2809-2813 (2000)</A> and
<A HREF="http://circ.ahajournals.org/cgi/content/full/104/13/1464"
TARGET="_blank">CIRCULATION; 104(13):1464-1470 (2001)</A>].
<P>Biogerontologist Aubrey de Grey believes that reversing
aging may actually be more feasible than slowing aging, in the same sense that is sometimes
more economical to periodically repair damage than to go to extraordinary expense to
slow the rate of damage. Dr. de Grey believes that the key to rejuvenation is the
repair of seven distinct kinds of damage that represent aging: cell loss, cell senescence,
extracellular protein cross-linking, nuclear DNA mutations, mitochondrial DNA mutations
and the accumulation of garbage inside cells as well as outside cells. He has characterized
the repair of these seven kinds of damage as
<a href="http://en.wikipedia.org/wiki/Strategies_for_Engineered_Negligible_Senescence"
target="_blank"><B>Strategies for Engineered Negligible Senescence</B></a> (<B>SENS</B>).
<P>The seven repair strategies that Dr. de Grey advocates can
be summarized: (1) Cell loss can be repaired (reversed) just by suitable exercise
in the case of muscle, but for other tissues it needs various
growth factors to stimulate cell division, or in some cases it
needs stem cells. (2) Senescent cells
can be removed by activating the immune system against them. Or
they can be destroyed by gene therapy to introduce "suicide genes"
that only kill senescent cells. (3) Protein cross-linking can
largely be reversed by drugs that break the links. But for some of the
links we may need to develop enzymatic methods. (4) Extracellular
garbage can be eliminated by vaccination that gets immune cells
to "eat" the garbage. (5) For intracellular junk we need to
introduce new enzymes, possibly enzymes from soil bacteria, that
can degrade the junk that our own natural enzymes cannot degrade.
(6) For mitochondrial mutations the plan is not to repair them but
to prevent harm from the mutations by putting suitably modified copies of
the mitochondrial genes into the nucleus by gene therapy. The
mitochondrial DNA experiences so much mutation damage because
most free radicals are generated in the mitochondria. If
mitochondrial DNA can be moved into the nucleus it will be
better protected from free radicals, and there will be better
DNA repair when damage occurs. All mitochondrial proteins would
then be imported into the mitochondria. (7) For cancer (the
most lethal consequence of mutations) the strategy is to use gene
therapy to delete the genes for telomerase and to eliminate
telomerase-independent mechanisms of turning normal cells into
"immortal" cancer cells. To compensate for the loss of telomerase
in stem cells we would introduce new stem cells every decade or so.
<P> For more background on Dr. de Grey's approach, see
<A HREF="http://www.gen.cam.ac.uk/sens/just7.htm" TARGET="_blank">
SENS Overview</A>.
<P>The ultimate rejuvenation, however, will occur further in the future with the advent
of molecular repair technology (nanotechnology) which can fix <I><B>all</B></I> kinds of
molecular damage due to aging (as detailed in the book
<A HREF="http://www.foresight.org/EOC/index.html" TARGET="_blank">
ENGINES OF CREATION</A> by <A HREF="http://www.foresight.org/FI/Drexler.html" TARGET="_blank">
K. Eric Drexler</A>).
<P><a href="#contents"> (return to contents)</a>
<H3><a name="conclusions">XXVII. AGING: CAUSE & CURE — SUMMARY & CONCLUSIONS </a></H3>
<P>What causes aging? In other words, what lies behind the progressive deterioration that
accompanies the passage of time after maturity — with special interest to humans. To
answer in outline form:
<UL TYPE="SQUARE">
<H4><LI>METABOLIC DAMAGE</LI></H4>
<UL TYPE="DISC">
<H5><LI>FREE RADICALS</LI></H5>
<H5><LI>GLYCATION</LI></H5>
</UL></UL>
<UL TYPE="SQUARE">
<H4><LI>CELLULAR SENESCENCE & DEATH</LI></H4>
<UL TYPE="DISC">
<H5><LI>TELOMERE SHORTENING</LI></H5>
<H5><LI>DECLINING & INADEQUATE DNA REPAIR & AUTOPHAGY</LI></H5>
<H5><LI>DECLINING & INADEQUATE ANTI-OXIDANT DEFENSE</LI></H5>
<H5><LI>DEFECTIVE CELL CYCLE CONTROL, PROTEASOMES, LYSOSOMES & HEAT SHOCK PROTEINS</LI></H5>
</UL></UL>
<UL TYPE="SQUARE">
<H4><LI>TOXIC & NON-TOXIC GARBAGE ACCUMULATION</LI></H4>
<UL TYPE="DISC">
<H5><LI>PROTEIN CROSS-LINKING & AGGREGATION</LI></H5>
<H5><LI>ADVANCED GLYCATION END-PRODUCTS (AGEs)</LI></H5>
<H5><LI>ATHEROSCLEROTIC AND AMYLOID PLAQUES</LI></H5>
<H5><LI>INFLAMMATORY CYTOKINES</LI></H5>
<H5><LI>LIPOFUSCIN</LI></H5>
<H5><LI>CORTISOL</LI></H5>
<H5><LI>METALS</LI></H5>
<H5><LI>DDT, PCBs, etc</LI></H5>
</UL></UL>
<P> An organism that can create fewer free-radicals in generating energy (more efficient
mitochondria), use less energy to live, have more effective antioxidant defenses, have
better DNA protection, have better DNA repair, have a better immune system and detoxify
more effectively in the liver — can reduce damage from endogenous & exogenous sources.
<P>Glucose is necessary for energy production, but glucose causes glycation of proteins.
Energy creation results in free radicals as a toxic byproduct. Toxic & non-toxic
garbage accumulation is primarily a problem for non-dividing cells (like neurons &
muscle cells) which cannot dilute-away the garbage. The damage which causes
aging is the damage due to necessary metabolism. This damage affects DNA repair, antioxidant
production, telomere length, cell-cycle control, proteosome function, etc. — resulting in
reduced capacity to cope with increasing levels of damage.
<P>Telomere shortening contributes to mortality only in a few tissues. Neurons & muscle
cells are non-dividing and are thus not affected by telomere shortening. Telomere
shortening may contribute to mortality most significantly for immune system cells
& arterial epithelial cells. Even if telomere shortening in the immune system is proven
to cause the majority of deaths in the very elderly, the mortality is better described as
"failure of the weakest link" (like the death of wild horses from worn-down
teeth) than as <B><I>aging</I></B>. If biological gerontologists are successful in finding
means to greatly increase human lifespan, then telomere shortening in proliferative
tissues may become far more relevant to human aging. (For non-dividing cells, notably
neurons, metabolic damage & garbage accumulation could be considered the "weakest
link" if it weren't for the fact that cell death is so different from cell
senescence.)
<P>Metabolic damage would be much less of a problem if its byproducts (cross-links, AGEs,
lipofuscin, etc.) could be eliminated — along with whatever toxins (lead, cadmium, DDT,
PCBs, etc.) manage to enter the organism. The so-called immortality of germ cells, bacteria
and <B><I>Hydra</I></B> [EXPERIMENTAL GERONTOLOGY 33(3):217-225 (1998)] is probably due to
the diluting-away of toxins (all of the <B><I>Hydra</I></B> cells are dividing cells).
Lobsters — which have been proposed as candidates for negligible senescence
— discard tissue by molting and appear to continue growing without ever maturing. Lobsters
express telomerase in all organ tissues and may avoid senescence by the same mechanism as
<I><B>Hydra</B></I> [FEBS LETTERS; Klapper,W; 439(1-2):143-146 (1998)].
<P> Why does CRAN (<A HREF="../calories/calories.html" TARGET="_blank">Caloric Restriction with
Adequate Nutrition</A>) extend lifespan? The most plausible explanation is that the lower
level of calorie utilization & energy production allows for lower levels of blood glucose
(less glycation) and less free radical production. Efforts to duplicate CRAN with a pill
or genetic manipulation probably have no chance of success.
<P>If the "accelerated aging" diseases
are a guide, damage to DNA — mitochondrial (mtDNA) and nuclear (nDNA) — are the
damage that is most central to aging. Damage to nDNA and nDNA repair capability
would be the worst because mitochondria (and mtDNA) can be replaced by lysosome
recycling. But the source of that nDNA damage would still be mitochondria.
Defective nDNA repair along with associated cell senescence & apoptosis leads
more to aging, whereas the nDNA damage itself leads
more to cancer. For mtDNA damage, the damage becomes most serious when the lysosomes are
no longer capable of removing defective mitochondria which are producing high levels of
free radicals. Free radicals are the primary cause of the nDNA and mtDNA damage in the
first place. Defective mitochondria play a central role in accelerated apoptosis, leading
to tissue degradation. If defective mitochondria which produce high levels of free radicals
are the major source of aging damage, then the most effective step towards slowing aging
would be improving lysosomal function by providing more efficient enzymes to the lysosomes.
<p>The maximum lifespan of one or a few individuals of a species is taken as a proxy for
the rate of aging of that species and for the idea that only extensions of maximum
lifespan are relevant to slow aging. But most people die of aging-related diseases:
cardiovascular disease, cancer, Alzheimer's Disease, etc. The damaging aging processes
that increase vulnerability to these diseases are more relevant to vast majority of
people than influences on maximum lifespan. For this reason it is not misleading to
speak of diabetes, tobacco, dietary AGEs, ultraviolet radiation and other exogenous
sources of tissue damage as accelerating aging — especially when the damage so
closely resembles the tissue damage normally associated with aging. For the vast
majority of people good genes can only reduce (not prevent) the aging effects of
damaging exogenous agents. (For more on this subject, see <a href="./longgene.html"
target="_blank">Is Longevity Entirely Hereditary?</a>)
<p>The "mechanisms of aging" tend to be quite tissue-specific. Replicative
senescence leads to aging of T cells and blood vessel endothelial cells, whereas
other forms of cell senescence leads to aging of stem cells in the pancreas and
selected areas of the brain. Non-mitotic cells such as neurons and myocytes are
more vulnerable to oxidative stress and DNA damage. Glycation leads to cross-linking
of extracellular proteins. For any particular individual, the combination of
heredity and environmental conditions will cause some tissues and organ systems
to age (or experience damage) more than others — and becoming the "weakest
link" leading to mortality. The number or individuals who do not succumb to
age-related death specific to a particular tissue or organ is a tiny minority.
<P>Until molecular repair technologies are available, good health practices,
supplements and organ transplantation are our best hope of bridging
the time between now and the Age of Negligible Senescence.
<P> To see what the elimination of aging would mean to me personally, read
my essay <A HREF="../lifeext/whylife.html" TARGET="_blank">Why Life Extension? </A>
<P><a href="#contents"> (return to contents)</a>
<H3><a name="references">XXVIII. BOOK REFERENCES (by publication date)
<BR>(references to scientific papers are incorporated in the text) </H3>
<UL>
<LI>AGING OF THE GENOMOE Jan Vijg 2007
<LI>AGING OF ORGANS AND SYSTEMS Richard Aspinall (Editor) 2003
<LI>AGING OF ORGANISMS Heinz Osiewacz (Editor) 2003
<LI>MODULATION OF AGING AND LONGEVITY Surish Rattan (Editor) 2003
<LI>AGING OF CELLS IN AND OUTSIDE THE BODY S.Kaul/R.Wadhwa (Editors) 2003
<LI>AGING AT THE MOLECULAR LEVEL Thomas von Zglinicki (Editor) 2003
<LI>AGELESS QUEST Leonard Guarente 2003
<LI>ANNUAL REVIEW OF GERONTOLOGY AND GERIATRICS (V.21) V.Cristofalo 2001
<LI>HANDBOOK OF THE BIOLOGY OF AGING E.Masoro/S.Austad (Editors) 2001
<LI>THE MITOCHONDRIAL FREE RADICAL THEORY OF AGING Aubrey de Grey 1999
<LI>BIOLOGY OF AGING (2nd Ed.) Robert Arking 1998
<LI>IMMORTALITY Ben Bova 1998
<LI>WHY WE AGE Steven N. Austad 1997
<LI>PRINCIPLES OF NEURAL AGING S.Dani,A.Hori & G.Walter 1997
<LI>HANDBOOK OF THE BIOLOGY OF AGING E.Schneider/J.Rowe (Editors) 1996
<LI>CELLULAR AGING AND CELL DEATH Holbrook,Martin,Lockshin (Editors) 1996
<LI>CHEATING TIME Roger Gosden 1996
<LI>REVERSING HUMAN AGING Michael Fossel 1996
<LI>THE CLOCK OF AGES by John Medina 1996
<LI> UNDERSTANDING AGEING Robin Holliday 1995
<LI> THE MOLECULAR BASIS OF AGING Alvaro Macieira-Coelho (Editor) 1995
<LI> GENES AND AGING M.S.Kanungo 1994
<LI> HOW AND WHY WE AGE Leonard Hayflick 1994
<LI> FREE RADICALS IN AGING B.P. Yu (Editor) 1993
<LI> LIFESPAN Thomas J. Moore 1993
<LI> STRESS, THE AGING BRAIN, AND THE MECHANISMS OF NEURON DEATH Robert Sapolsky 1992
<LI> LIFE SPAN PROLONGATION V. Frolkis & K. Muradian 1991
<LI> AGING, SEX AND DNA REPAIR Carol & Harris Bernstein 1991
<LI> LONGEVITY, SENESCENCE AND THE GENOME Caleb E. Finch 1990
<LI> LIPOFUSCIN AND CEROID PIGMENTS Edwardo Porta (Editor) 1989/1990
<LI> BEYOND THE HELIX Carol Kahn 1985
<LI> MAXIMUM LIFESPAN Roy Walford 1983
</UL>
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MECHANISMS OF AGING
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# Mechanisms of Aging
**by Ben Best**
### Please take the ***short***
[Life Extension Values Clarification Survey](./LE_Survey.php)
**Note: This monograph does NOT have a terminal copyright date — development is ongoing**
### CONTENTS: LINKS TO SECTIONS BY TOPIC
1. [DEFINITION OF AGING](#define) - [SYMPTOMS OF AGING](#symptoms) - [AN OVERVIEW OF AGING AND OF AGING THEORIES](#theories) - [EVOLUTION THEORY AND SPECIES-SPECIFIC AGING](#evolution) - [SEX AND AGING](#sex) - [AGING OF OTHER ORGAN SYSTEMS](#other) - [THE FREE RADICAL THEORY OF AGING](#radical) - [MITOCHONDRIA AND AGING](#mitochondria) - [THE GLYCATION THEORY OF AGING](#glycation) - [PROTEINS DAMAGE AND MAINTENANCE IN AGING](#protein) - [DNA DAMAGE AND DNA REPAIR](#dna) - [TELOMERES AND AGING](#telomeres) - [CELLULAR SENESCENCE AND APOPTOSIS IN AGING](#senescence) - ["ACCELERATED AGING" DISEASES (SEGMENTAL PROGERIA)](#progeria) - [LONGEVITY GENES (FLIES & WORMS)](#longevity)- [LONGEVITY GENES (MAMMALS)](#longevity2)- [SIRTUINS AND DEACETYLASES IN AGING](#silencing) - [HORMONES AND AGING](#hormones) - [THE IMMUNE SYSTEM AND AGING](#immune) - [INFLAMMATION AND AGING](#inflame) - [ACCUMULATION OF TOXINS AND CHEMICAL GARBAGE](#toxins) - [CANCER AND AGING](#cancer) - [BIOMARKERS OF AGING](#biomarkers) - [CALORIC RESTRICTION WITH ADEQUATE NUTRITION (CRAN)](#cran) - [OTHER METHODS TO SLOW AGING](#methods)- [REGENERATIVE MEDICINE, STEM CELLS AND REJUVENATION](#rejuvenate)- [AGING: CAUSE & CURE — SUMMARY & CONCLUSIONS](#conclusions) - [BOOK REFERENCES](#references)
### I. DEFINITION OF AGING
**Aging** is a syndrome of changes that are deleterious, progressive,
universal and thus far irreversible. Aging damage occurs to molecules (DNA,
proteins, lipids), to cells and to organs. Diseases of old age (diseases which
increase in frequency with age, such as arthritis, osteoporosis, heart disease,
[cancer](../health/cancer.html),
[Alzheimer's Disease](../lifeext/Alzheimer.html),
etc.) are often distinguished from aging
***per se***. But even if the aging process is distinct from
the diseases of aging, it is nonetheless true that the damage associated with
the aging process increases the probability that diseases of old age will occur.
Some gerontologists prefer to use the word **senescence** because
"aging" implies that the passage of time necessarily results in
***deterioration***
(biological entropy) — which is certainly not true during the early,
***developmental***, time of life (before the age of 10 or 12 in humans).
I will retain the word "aging" because I
believe the association between aging & deterioration is universal
as adult years progress and because the distinction between aging & development is very
strongly established in conventional language. Also, shorter words make
for slightly faster reading.
[(return to contents)](#contents)
### II. SYMPTOMS OF AGING
One can catalog
changes that typically occur with age. For people of developed countries age
changes include: A loss of hearing ability, particularly for higher
frequencies. There is a decline in the ability to taste salt&bitter
(sweet&sour are much less affected). There is a reduction of the
thymus gland to 5−10% of its original mass by age 50.
Levels of antibodies increase with aging. One third
of men and half of women over 65 report some form of arthritis.
About half of those aged 65 have lost all teeth. The elderly require twice
as much insulin to achieve the glucose uptake of the young. There is
reduced sensitivity to growth factors & hormones due to fewer receptors
and dysfunctional post-receptor pathways. The temperature needed to
separate DNA strands increases with age. Weight declines after age 55
due to loss of lean tissue, water and bone (cell mass at age 70
is 36% of what it is at age 25). Body fat increases to age 60.
Muscle strength for men declines 30−40% from age 30 to age 80.
Reaction time declines 20% from age 20 to 60. Elderly people tend to
sleep more lightly, more frequently and for shorter periods — with a
reduction in rapid eye-movement (REM) sleep. Neurogenesis in the hippocampus
declines with age. Degree of saturation of fats drops by 26% in the brains
of old animals. Presbyopia (reduced ability to focus on close-up objects)
occurs in 42% of people aged 52−64, 73% of those 65−74
and 92% of those over age 75.
Most people over age 75 have cataracts. About half of those over 85 are
disabled (defined as the inability to use public transportation). Over
75% of people over 85 have 3−9 pathological conditions, and the cause of
death for these people is frequently unknown.
Aging changes are frequently associated with an increase in
likelihood of mortality, but this is not necessarily the case. For
example, graying of hair is a symptom of aging, but graying does not increase
likelihood of mortality. Aging changes which are not associated with
a specific disease, but which are associated with a generalized increase
in mortality would qualify as **biomarkers** of aging — and would
distinguish **biological age** from **chronological age**.
Biomarkers would be better predictors of the increased likelihood
of mortality (independent of specific disease) than the passage of
time (chronological age). Cross-linking of collagen, insulin resistance
and lung expiration capacity have been proposed as candidates but, as
yet, no biomarkers of aging have been validated and universally accepted.
[(return to contents)](#contents)
### III. AN OVERVIEW OF AGING AND OF AGING THEORIES
Many scientists have wondered whether a single cause (probably cellular
or hormonal) lies behind all aging phenomena — or whether aging is inherently
multi-faceted. Differences in lifespan between species raise critical
questions, in this regard. Why is a rodent old at 3 years, a horse old at
35 years and a human old at 80 years? Aren't the cells much the same? Why
is it that at age 3 about 30% of rodents have had cancer, whereas at age
85, about 30% of humans have had cancer? Some species (such as lobsters,
alligators and sharks) show few signs of aging. Cancer cells, stem
cells and human germ cells seem "immortal" when compared to other cells.
![[GRAPH OF SURVIVAL AGAINST AGE]](lifespan.gif)
When discussing aging it is important
to distinguish two points on survival curves.
**Mean lifespan** (average lifespan) corresponds to the age at
which the horizontal line for 50% survival
intersects the survival curve. **Maximum
lifespan** corresponds to the age at which
the survival curves touch the age-axis (0%
survival) — and this represents the age
at which the oldest known member of the
species has died. (In animal studies, maximum lifespan is typically taken to be
the mean lifespan of the most long-lived 10%.) Curve A as shown is a
pure exponential decay curve. Curve B corresponds to the
survival of small animals, such as mice or squirrels in a natural
environment. Human survival was still close to
curve B in ancient Rome when average lifespan was 22 years, but by the
mid−1800s the typical North American lived to be 40 — more like curve C.
Today, people in the most developed countries have an average lifespan of about
80 — resembling curve D. Reduction of infant mortality has
accounted for most of the increased longevity, but since the 1960s mortality
rates among those over 80 years has been decreasing by about 1.5%
per year. Maximum lifespan for humans, however, has remained
about 115−120 all through known history. The longest documented human lifespan
has been for Frenchwoman Jean Calment who lived 122.3 years.
Curing specific diseases such as heart
disease or cancer can do no more than further "square" the survival curve
(toward curve E), with no effect on maximum lifespan. Curing cancer would add about
2 years to human life, whereas eliminating heart disease would add 3 or 4 years.
**Mean lifespan** varies with susceptibility to disease, accident & homicide/suicide,
whereas **maximum lifespan** is determined by "rate of aging". In aging
research, maximum lifespan is regarded as a proxy for aging. Chemicals, calorie restriction
with adequate nutrition, or other interventions which increase maximum lifespan are said
to have slowed the aging process.
If human beings were free of disease & senescence the only
causes of death would be accident, suicide & homicide. Under such
conditions it is estimated that from a population of one billion, a
12-year-old would have a median lifespan of 1,200 years and a maximum
lifespan of 25,000 years.
In 1825 an English actuary named Benjamin Gompertz discovered that likelihood of
dying increases exponentially with age after maturity — an empirical observation that
has stood the test of time. A 35-year-old is twice as likely to die as a 25-year-old
and a 25-year-old is twice as likely to die as a 15-year-old. The exponential increase
does not continue past age 80 and death rate may even decline after age
110 [SCIENCE 280:855-860 (1998)]. (Medflies — Mediterranean fruit flies — show a
plateau of linear rather than exponential death rate when 20-25% of the population
remains). Similarly, the risk of getting
[Alzheimer's Disease](../lifeext/Alzheimer.html)
doubles every 5 years past
the age of 60 — probably plateauing after age 90 (when over half the population
is already demented). Cancer rate increases exponentially with age, but also seems
to plateau in the very elderly. One explanation might be that subsets of the population
that are considerably more hardy due to genetics or behavior may remain after the more
heterogenous majority have died. Another explanation suggests the complete elimination
of the forces of natural selection at the oldest ages — which causes subsequent survival
to be completely the result of genetic "random drift" [PROCEEDINGS OF THE
NATIONAL ACADEMY OF SCIENCES (USA) 93:15249-15253 (1996)].
[Causes of death](../lifeext/causes.html) in middle-age tend to
be due to diseases affecting high-risk individuals (cancer, diabetes, hypertension, etc.),
whereas the elderly are more vulnerable to multiple pathologies due to vulnerability
of aging organs & tissues [JOURNALS OF GERONTOLOGY 58A(6):B495-B507 (2003)].
Attempts to classify theories of aging have led to the two major
classifications **programmed aging** and **wear&tear aging**.
**Programmed aging** would be aging due to something inside an
organism's control mechanisms that forces elderliness & deterioration —
similar to the way genes program other life-stages such as cell
differentiation during embryological development or sexual maturation at
adolescence. By contrast aging due to **wear&tear** is not the
result of any specific controlling program, but is the effect of the sum
effect of many kinds of environmental assaults — ie, damage due to radiation,
chemical toxins, metal ions, free-radicals, hydrolysis, glycation,
disulfide-bond cross-linking, etc. Such damage can affect
genes, proteins, cell membranes, enzyme function, blood vessels, etc.
When Pacific salmon have lived in the ocean for 2 or 3 years, they
make an arduous upstream journey against a raging riverswim until they find a place
suitable for spawning. After spawning, the adrenal gland releases massive amounts of
corticosteroids — leading to rapid deterioration. It would be costly for the species
to have salmon that could live another year and repeat the journey — or compete with the
offspring for food. Although this process is obviously
"programmed", it is inaccurate to describe it as
"aging". Programmed death, rather than programmed aging, is a
common phenomenon among animals that reproduce only once.
Grazing animals show wear-and-tear to their teeth to the point where
they can no longer eat, and they die of starvation. Again, it stretches the
point to say the teeth are aging. The teeth of rabbits (like human
fingernails) continue to grow as wearing occurs — and in this sense are
"programmed" to compensate for "wear&tear". Why don't
grazing animals have teeth that continue to grow?
Human beings can replace tissue, capillaries and bone in wound-healing, yet
cannot regrow a severed limb the way a salamander can. Why isn't human
DNA "programmed" to re-grow kidney
or liver tissue as it ages? Planarians (flatworms) have a pool of stem
cells which can replace any of their fully differentiated cells. Programming
that compensates for wear & tear should be distinguished from programming
that causes deterioration.
[(return to contents)](#contents)
### IV. EVOLUTION THEORY AND SPECIES-SPECIFIC AGING
Russell Wallace, who with Charles Darwin discovered natural
selection, speculated that longevity much beyond the age of
procreation would be a disadvantage for a species. Parents
would threaten their children by competition for resources. This would
imply an evolutionary advantage to genetically programmed aging. The
programmed self-destruction with corticosteroids by Pacific salmon
after spawning — and whose decaying bodies provide nutrient for
their offspring — may be severe example indicating the possiblity
of programmed senescence. But as biologist Peter Medawar noted, there
is circular reasoning in claiming that senescence evolved so that
non-senescent individuals could more readily survive. If there were
no senescent, poorly-reproducing individuals, there would be no need
for replacement.
If aging were the product of evolutionary forces, aging could
reasonably be expected to result from programming. But since most
animals in the wild die of accident, attack or disease
it seems questionable that evolutionary forces determine aging. Robins
in the wild, for example, have an estimated 12-year maximum lifespan
and a 40% chance of surviving any given year. With a (0.4)12
— or 1 in 60,000 — chance that a robin can avoid accident, attack or disease
for 12 years, there would seem to be little opportunity for natural selection
to play a role in the evolution of senescence. Against this argument is
evidence that early stages of senescence reduce the ability of an animal
to survive — thereby causing earlier selection against older animals.
An alternative to the view that senescence is the product of evolution
compares genetic programming to the engineering of a fly-by satellite
designed to gather data about a planet. The engineering is focused on
ensuring that the satellite reaches its destination and performs its
data gathering/transmission when passing the planet. Beyond the planet
it is a matter of indifference to the engineers how long the satellite
continues to function — random decay occurs. Applying the analogy,
the satellite passing the planet is like an organism passing its
reproductive period. Once the objectives of reproduction & parenting
have been achieved the organism decays by random malfunction.
**Maximum lifespan of many animal species**| Maximum lifespan of many animal species |
The vast range of maximum lifespan differences between species
provides convincing evidence that longevity is genetically influenced.
An elephant lives about 10−20 times longer than
a mouse, yet both animals have roughly the same number of lifetime
heartbeats — the elephant at 30 per minute and the mouse at
300 per minute. Both species take about 200 million breaths
in a lifetime. And both species have a **metabolic potential** (total
kilocalories used per gram of body weight per lifetime) of about 200 kcal.
This figure is much the same for other mammals, but humans are exceptional
with a metabolic potential of 800 kcal. Brains use more energy than any other
human organ. (**Basal metabolic rate** for
humans is about 80 watts = 70 Calories per hour.) Birds
have a metabolic potential of 1,000 to 1,500 kcal.
Gerontologists who compare the longevity of species explain
this discrepancy by saying that while body weight correlates well
with longevity, there is a better correlation with brain weight for primates.
For other species brain size may be more related to motor
function than to cognitive capacity.
Flight, like brain weight, also confers a longevity advantage. Finches &
robins live about 3 times as long as rodents the same
size. Flying squirrels live twice as long as their close relatives
the chipmunks. Parrots have a maximum lifespan in excess of 90 years. The
Andean condor may be the most long-lived of any bird, but its maximum
lifespan has not been confirmed.
Gross attributes of species typically associated with greater longevity are:
large size, ability to fly, brainy, a spiny or shelled encasement, and cold-blooded. All
but the last attribute reduce vulnerability to predators. Porcupines are the longest-lived
rodents. Naked mole rats, by living underground, are also
safer from predators and live significantly longer than similarly-sized rats.
All adaptations that afford protection from predators and other hazards justify
greater developmental resources to build a more durable
animal with a longer maximum lifespan.
Opossums evolving on an island free of predators have been shown to have
substantially longer lifespans and smaller litters than opossums living on
the nearby mainland [JOURNAL OF ZOOLOGY; 229:695-708 (1993)]. Where competition
between individuals of a species for mates & resources is more important than
survival against predators and
other hazards, evolution causes more investment in making a more hardy & durable animal —
which includes having fewer offspring on each birthing (but more total offspring
over the lifetime) — with each offspring receiving more care and resources. Gene
survival can be better promoted (up to a point) by extending lifespan and reproductive
period of reproductively successful adults than by creating many more offspring,
a signficant number of whom will not survive to become reproductive adults.
Large size also confers protection against predators and confers
an improved ability to escape dangerous environments. Metabolic rate decreases
proportionally with increases in body size, which allows larger animals to survive longer
when food & water are scarce. [For a sphere, surface area **S = 4πr2**
and volume **V = (4/3)πr3**, which means that **S**/**V** varies
inversely with **r** (radius). Because heat is generated in the volume and dissipates
in the surface area, relative dissipation decreases with an increase in radius because of
the decrease in **S**/**V**.] Large animals are better able to withstand extreme
temperatures because of greater body mass. Large animals and birds are more easily able
to travel long distances to find food or less harsh environments.
Cold-blooded animals needn't expend energy to maintain body temperature and
therefore generate fewer free-radicals. Also, the rate of chemical reactions more than
doubles for each 10ºC increase in temperature. Cold-blooded animals may use one-tenth
as much energy as warm-blooded animals of the same body weight. The alligator, Galapagose
tortoise and lake sturgeon combine large size with cold-bloodedness. Turtles live
longer than other reptiles because of the shell which protects against predators.
With the combination of hard shell, large size and cold-bloodedness, it is not
surprising that the Galagose turtle is probably the most long-lived vertebrate.
Hard shell, cold-bloodedness and the ability to reduce metabolic rate allow
some [bivalves](http://en.wikipedia.org/wiki/Bivalvia)
to live nearly four
centuries [[GERONTOLOGY; Philipp,EER; 56(1):55-65 (2010)](http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=000221004)].
A short-lived organism would waste metabolic
energy by over-investing in anti-oxidant or DNA-repair enzymes when the
energy could be spent on rapid growth and reproduction. When a species has fewer
predators, evolution invests fewer resources into speedy reproduction and more genetic
resources (DNA repair, etc.) into a longer reproductive period (longer life).
In the case of birds, the mitochondrial membranes contain more unsaturated fat making
them less vulnerable to lipid peroxidation. And the protein complexes of the respiratory
chain of mitochondria generate fewer free radicals in birds than in mammals.
It is conceivable that an animal with well-engineered cells could live many centuries.
Human germ cells have arguably lived for millions of years through an investment in
DNA-repair enzymes, antioxidant enzymes and telomerase.
Evolutionary biologists are able to use artificial selection in the
laboratory experimentally (rather than passively studying natural
selection in the wild) to seek the evolutionary determinates of longevity.
Michael Rose at the University of California has shown that ***Drosophila***
(fruit-flies) bred for 15 generations by disposing of eggs laid early in life and
only using eggs that were laid toward the
end of reproductive life achieved maximum lifespans 30% greater than that of controls.
The long-lived strains had increased levels of SOD, CAT and xanthine dehydrogenase
as well as increased levels of heat shock proteins conferring stress
resistance [JOURNALS OF GERONTOLOGY 55A(11):B552-B559 (2000)]. Hsp22 heat shock
protein expression was 2−10 times greater in the long-lived strains as compared to
controls. Transgenic ***Drosophila*** (ie, fruit flies with artificially altered
genes) with extra copies of hsp70 genes live nearly 8% longer than controls following
heat treatment [NATURE; Tatar,M; 390:30 (1997)].
Dr. Rose has also observed the experimental increase in mortality associated
with aging ceases late in life [PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY; Rose;MR;
78(6):869-878 (2005)]. Although mortality rates remain very high in late-life, they
plateau. Studies of inbred ***Drosophila*** indicate that the plateauing
cannot be due to genetic variation. From his evolutionary biology perspective Dr. Rose
associates this phenomenon with a late-life end of the force of natural selection.
This would imply that senescence is genetically programmed and that studying
the genetics of the plateau could be the key to understanding the genetics of
longevity.
[(return to contents)](#contents)
### V. SEX AND AGING
In nearly every culture on earth women outlive men — significantly
so in the oldest years. But the men who do survive to become
elderly are hardier than the women. A US National Institute of Aging study
showed that 44% of men over age 80 are "robust and independent"
compared with only 28% of women. And the percentage of surviving males
increases from 15% at age 100 to 40% at age 105 in the United
States.
![[Graph of
Fertility Decline]](fertile2.gif)
If aging has been programmed
by evolutionary forces, sex could
be a very important contributor to
the program. The reproductive
organs of the human female exhibits
a rate of aging that is among
the most rapid of body systems. The
complete shutdown of female
fertility at menopause may be of
value in preventing the birth
of deformed children or death in
childbirth of a mother who has several
dependent children. For a species
with a lengthy parenting period, it
makes sense for fertility to cease
long before the debilities of
advancing age begin.
**Gonadotropin** hormones from
the pituitary gland are controlled by
**gonadotropin-releasing hormone**, a
10-amino-acid peptide originating
in neurons located in the **arcuate nucleus** of the hypothalamus. The two
gonadotropin hormones (**FSH** & **LH**) are the same for females as for males,
although their function is very different. Simplistically, FSH stimulates egg
production in females & sperm production in males, whereas LH stimulates
estrogen production in females & testosterone production in males.
In fertile females **FSH**
(**Follicle-Stimulating Hormone**) accelerates the growth of 6−12 primary
follicles in the ovary each month — one of which may become a mature
ovum. The follicles secrete estrogens, the most powerful of which
is **estradiol**. A sudden increase in **LH** (**Luteinizing Hormone**) usually
triggers **ovulation** (follicle rupture with discharge of the ovum) and
the conversion of the follicle to the **corpus luteum** ("yellow body")
— which also secretes estrogen, but primarily secretes **progesterone**.
Progesterone stimulate the walls of the uterus to prepare it for implantation
of the fertilized ovum. If pregnancy occurs, progesterone inhibits
ovulation (by suppressing FSH & LH) and promotes uterine development
until the placenta becomes more mature. (Pro**gesterone** is so-named
because it promotes **gestation**, ie, the growth of offspring in the
womb).
**Graph of Female Hormonal Cycles**| Female Hormonal Cycles |
Aside from their role in the
monthly cycle, estrogens are
responsible for the development
and maintenance of the female
sexual organs, cause the deposition
of fat in the breast&buttocks
(which contributes to the feminine
figure) and have a potent effect
on bone development.
Menopause is the event in a
woman's life when her ovary
literally runs out of eggs. The loss of follicles to produce estradiol causes an end to
menstrual cycling and production of estrogen & progesterone by the ovary. At
age 30, a woman's period is normally
28−30 days, but by age 40
her period is typically
closer to 25 days and her rate of egg-loss has accelerated. Further shortening
(accompanied by periods when no
ovulation
occurs) eventually leads to menopause at an average
age of 50 (plus or minus 10 years). The menopausal woman often experiences
anxiety, irritability and fatigue. Beginning before menopause most women
experience "hot flashes", ie, 3 minute surges
of blood to the skin of the chest, shoulders & face leading to sudden
hotness & sweating. Hot flashes are associated with a pulsatile release
of LH from hypothalamic neurons associated with body temperature elevation.
Estrogen therapy eliminates hot flashes. The rate of loss of ovarian follicles
doubles around age 35, raising the suspicion that a hypothalamic mechanism
may be the ultimate cause of menopause [SCIENCE 273:67-70 (1996)].
The most serious complications of menopause are osteoporosis and a
decline in cardiovascular health. The Framingham Heart Study demonstrated
that between ages 35 to 65 men have 10 times the incidence of heart attack
as women — probably because estrogen protects against heart disease.
Estrogen elevates HDL cholesterol and reduces LDL cholesterol in the
bloodstream.
After menopause, nipples decrease in size and the surrounding alveolar
tissue shrinks. Erection of these tissues with external stimulation is more
difficult. Vaginal contractions during orgasm is reduced to 4−5 at
0.8-second intervals from 8−12 in young adults.
The testes have been regarded as the source of maleness
at least since ancient Rome, where eunuchs & women were not
permitted to "testify" (**testis** is Latin for "witness"). In
the male, LH stimulates secretion of testosterone by the
interstitial cells of Leydig in the testes. FSH stimulates
spermatogenesis in the seminiferous tubules of the testes.
Testosterone promotes development of male sexual organs in the
foetus. At puberty testosterone stimulates hair growth on the
face & pubis, causes enlargement of the larynx to deepen the
voice, increases skin thickness, causes a 50% increase in muscle mass,
promotes bone growth, increases basal metabolism up to 15% and
increases red blood cell concentration.
![[Graph of Male Testosterone Decline]](testost.gif)
There is no sudden "andropause"
event in males that is comparable to
the menopause event of females. Instead,
testosterone levels tend to decline
gradually with age. This decline occurs
most dramatically in those with cardiovascular disease or a predisposition
to adult-onset diabetes. Although sperm
count declines, fatherhood has been
verified for a male as old as 94.
Semen production declines in the prostate
as a man ages — and the smooth muscle is
replaced by overgrowing connective tissue
that enlarges the prostate,
blocks urine and can lead to cancer.
85% of men over age 50 have symptoms arising from **benign prostatic
hyperplasia** — a noncancerous overgrowth of prostate tissue possibly caused by
excessive expression of the anti-apoptosis protein **bcl−2** [HUMAN PATHOLOGY
27:668-675 (1996)]. In some tissues testosterone must
be converted to **dihydrotestosterone** (by
the enzyme **5−α reductase**) in order
to act. This occurs most notably in the
prostate gland, which produces semen (a
mixture of sugars, protein and water).
Dihydrotestosterone has also been
implicated in baldness. The European drug Permixon (an extract of the
saw palmetto berry) inhibits 5−α reductase, and is used to prevent
prostate hypertrophy and prostate cancer. The
[Life Extension Foundation](http://www.lef.org)
sells saw palmetto berry extracts as a dietary supplement for this purpose.
Testosterone has been used in elderly men for "rejuvenation" — to restore
virility & muscle strength. Testosterone increases the risk of cardiovascular disease
— by increasing blood pressure, by lowering HDL cholesterol and by
elevating LDL cholesterol. These same dangerous side effects are also
seen in athletes who attempt to use androgens or other anabolic
steroids to improve athletic performance. Eunuchs reportedly live
longer, although there have been no controlled clinical trials to
prove this observation. Sterilization of a dog or cat (male or female)
adds a couple of years to its lifespan. Any reduction in sex hormones would be
expected to reduce cell proliferation and hence reduce the probability of cancer.
Male libido peaks in mid-adolescence, and does not correlate
exactly with testosterone blood levels. In elderly men it may take
from 10 seconds to several minutes to get an erection, in contrast
to 3−5 seconds in young men. Contractions of the penile urethra during
orgasm is reduced to 1−2 contractions per 0.8-seconds from 3−4 in young
adults. Ejaculatory distance is reduced from 12−24 inches to 3−5 inches.
[For more about sex and aging, see [Sex Hormone Replacement in Older Adults]](../health/SexHormR.html)
[(return to contents)](#contents)
### VI. AGING OF OTHER ORGAN SYSTEMS
Aging in the female reproductive system provides the best example of
programmed aging in mammals. For many other organs — particularly
the heart, brain, lung and kidney — specific disease states associated
with aging are of more significance than generalized deterioration. There
is wide variation in the health status of specific organs among the
elderly.
Skin, lungs, muscles, blood vessels and organ-function in general
is adversely affected by protein cross-linking — which is increased in
diabetes. Because most of those 65 years of age have at least some
symptoms of subclinical diabetes and because most of the symptoms of aging
are accelerated in diabetes, diabetes figures strongly when the elderly
are described in terms of averages. Generalized reduction in blood flow
due to atherosclerosis also has an adverse effect on most organ systems
— some more than others. Both protein cross-linking and cardiovascular
deterioration are strongly influenced by genetics and environmental
influences (diet, smoking, etc.).
With aging there is normally an age-related decrease in
[insulin
sensitivity](../health/MacroNut.html#syndrome) as well as of resting metabolic rate per unit of fat-free
mass. These changes may not occur for those who maintain high levels of
aerobic exercise [[JOURNAL OF APPLIED PHYSIOLOGY; Clevenger,CM; 93(6):2105-2111 (2002)](http://jap.physiology.org/cgi/content/full/93/6/2105)
and [AMERICAN JOURNAL OF PHYSIOLOGY; van Pelt,RE; 281(3):E633-E639
(2001)](http://ajpendo.physiology.org/cgi/content/full/281/3/E633)]. A study of very long-lived persons (over age 95) did not show a
decline in resting metabolic
rate [[THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM; Rizzo,MR;
90(1):409-413 (2005)](http://jcem.endojournals.org/cgi/content/full/90/1/409)], but another study of those over age 90 did show
reduced metabolic rate [JOURNAL OF GERONTOLOGY; Frisard,MI; 62A(7):752-759
(2007)]. Whether survival is due to this trait or whether the trait is a feature
of aging cannot be distinguished by cross-sectional studies.
The kidney provides perhaps the most striking example of individual
variation in the effects of aging. On average, kidney weight declines
about 15% between ages 40 and 80. The kidney's filtering capacity
for the average 90-year-old is typically half what it is for the
average 20-year-old. But high blood pressure and diabetes are particularly
damaging to kidney function. A 20-year longitudinal study showed no
change at all among elderly men who had no health problems. If this
result can be extrapolated it would mean that within the human maximum
lifespan there is no significant kidney deterioration in the absence of disease
conditions. (For a discussion of the issue of whether dietary protein can
harm kidney function, see my essay
[Does Excess Protein Cause Kidney Damage?](../health/kidney.html)).
Cardiovascular disease is the [most
frequent cause of death](./causes.html) among those over age 85.
The left ventricle of the heart increases in size with age (hypertropy)
due to an increase in size of the heart muscle cells that must work
harder to pump blood through a circulatory system that has narrower
channels and reduced elasticity. Lipofuscin content of heart muscle
cells increases from about 1% in the young to over 5% in
the old. Arteries thicken with age such that about three-quarters of
elderly people have increased blood pressure (both systolic & diastolic).
But, stated conversely, about a quarter of elderly people do ***not***
have elevated blood pressure. According to the Framingham Heart Study, systolic
blood pressure is a better predictor of mortality than diastolic blood pressure.
Hypertension is defined as a systolic blood pressure greater than 160mm Hg.
Hypertension is present in 5% of those aged 60 and nearly one quarter
of those aged 75-80. While heart attacks from ischemia account
for 43% of deaths for those 65−74 years of age, it accounts for only
8% of deaths for that age group in Japan (where death-rate from
stroke is much higher). (For more details concerning cardiovascular
disease, risk factors and prevention — see my essays
[Sudden Cardiovascular Death](../health/cardio1.html) and
[Prevention of Cardiovascular Disease](../health/cardio2.html).)
**Aerobic capacity decline** | Aerobic capacity decline |
Aerobic capacity ([VO2 max](http://en.wikipedia.org/wiki/VO2_max) — liters of oxygen consumed per
minute during peak exercise) declines increasingly steeply with age, and
declines more steeply in men than in women. Although exercise increases
aerobic capacity at any age, exercise does not prevent accelerated
decline [[CIRCULATION; Fleg,JL; 112(5):674-682 (2005)](http://circ.ahajournals.org/cgi/content/full/112/5/674)].
The claim that all people lose about 100,000 neurons per day has not
been supported by modern research. 2% of neurons are lost, on average,
between ages 20 and 90 (up to 40% of this loss in the frontal cortex).
Those over age 86 show an average 10% decline in brain weight from age 20.
Between age 30 and 90 brain volume declines an average of 14% in the
cerebral cortex, 35% in the hippocampus and 26% in cerebral
white matter. But ***averaging*** can be misleading, because the
elderly include many people with considerable dementia and others with
little or none. Nonetheless, a cross-sectional
[Magnetic Resonance Imaging](http://en.wikipedia.org/wiki/Magnetic_resonance_imaging) (MRI) study of healthy
volunteers showed age-related declines in the volume of gray matter in
association area (rather than sensory areas) of the cerebral cortex,
particularly in the prefrontal
cortex [[CEREBRAL CORTEX; Raz,N; 7(3):268-282 (1997)](http://cercor.oxfordjournals.org/cgi/reprint/7/3/268)]. Dementias
are more common among the
elderly who develop cardiovascular disease. Dramatic reduction in cerebral
blood flow and in brain oxygen&glucose utilization is frequently seen after
the 8th decade of life. Although most dementias are due to
[Alzheimer's Disease](../lifeext/Alzheimer.html),
at least 20% of dementias are due to stroke(s).
Skeletal muscles are "fast-twitch" or "slow-twitch".
**Fast-twitch muscles** ("white meat") can deliver much power
over short periods through energy from anaerobic (oxygen-free) phosphagen
(creatine phosphate) and glycogen/lactic-acid metabolism.
**Slow-twitch muscles** ("dark meat") provide
endurance with aerobic metabolism — using more mitochondria, more
myoglobin and more capillaries per square inch. Sprinters&jumpers have
more fast-twitch muscle, whereas marathoners&swimmers have more slow-twitch
muscle. Posture is maintained with slow-twitch muscles. Aging results in
greater loss of fast-twitch than slow-twitch muscle. Muscle fibers are
replaced by fat & connective-tissue. Mitochondria die. Exercise can
slow this deterioration because fast-twitch fibers atrophy due to loss of
the nerves that innervate them (a loss possibly due to disuse).
Muscles in the iris of the eye atrophy, and pupil size reduces, with age
— increasing the need for illumination. The lens thickens and becomes
yellowed, reducing green-blue-violet discrimination. (Elderly painters
use less violet & dark blue because the colors look the same.)
Collagen & elastin in tendons & ligaments become less resilient
and more fragmented as a person grows older, particularly due to
[glycation](#glycation)
(cross-linking of proteins by sugar). Articular cartilage becomes
frayed and the synovial fluid between joints becomes "thinner". Decline
in circulatory function contributes to this process. Glycation of collagen &
elastin is accelerated in diabetics due to high blood sugar.
Hair graying accompanies aging regardless of gender or race. By 50 years
of age approximately 50% of people have 50% gray
hair [[MICRON; Van Neste,D; 35(3):193-200 (2004)](http://www.ncbi.nlm.nih.gov/pubmed/15036274)].
Aging of skin is commonly divided into "chronological aging" and
"photoaging", with up to 80% of skin aging attributed to
photoaging in non-smokers. Photoaging is due to ultraviolet (UV) light,
which activates inflammatory cytokines & metalloprotein collagenases
as well as inducing free
radicals [[ARCHIVES OF DERMATOLOGY; Fisher,GJ; 138(11):1462-1479 (2002)](http://archderm.ama-assn.org/cgi/content/full/138/11/1462)]. UV
radiation generates singlet oxygen which both activates metalloproteinases and
causes large scale deletions of mitochondrial
DNA [[JOURNAL OF BIOLOGICAL CHEMISTRY; Berneburg,M;
274(22):15345-15349 (1999)](http://www.jbc.org/cgi/content/full/274/22/15345)]. [Carotenoids](../nutrceut/phytochemicals.html#carotenoids), especially lycopene, are particularly effective
quenchers of singlet oxygen [ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS;
Di Mascio,P; 274(2):532-538 (1989)].
Collagen & elastin also cross-link in skin, resulting in a loss
of elasticity. The protein **keratin** in fingernails is also a component
of the outer layer of skin (epidermis), which provides "water-proofing".
The epidermis thins with age, leading to wrinkles. Decreased secretion
by sweat glands increases vulnerability to heat stroke. When the
**melanocytes** (cells that produce the skin&hair-coloring substance
**melanin**)
associated with hair follicles cease functioning, hair turns white. Partial
reduction of melanocyte function results in hair that appears "gray".
Yet 90% of Caucasians show ***increased*** melanin in the form
of brownish spots on the back of their hands ("liver spots").
Although heat waves tend to lead to increased mortality among the elderly,
those affected are generally persons with chronic disease conditions and unhealthy
lifestyles. There is little alteration of thermoregulation with age among the
normal elderly [[JOURNAL OF APPLIED PHYSIOLOGY; Kenney;LW; 95(6):2598-2603 (2003)](http://jap.physiology.org/cgi/content/full/95/6/2598)].
Loss of flexibility of the proteins collagen & elastin in the lung
results in loss of elastic recoil. It becomes too difficult to fully
exhale, which reduces air exchange, reducing the capacity to do work.
Oxygen-to-tissue transfer rate is often halved by age 70.
Bone is typically 25% water, 30% soft tissue (cells & blood
vessels) and 45% mineral deposits (mostly calcium). Most of the white
ash remaining after cremation is calcium, lead, zinc and potassium from
bone. Both men & women lose bone mass between the ages of 39 and 70
**(osteoporosis)**,
but post-menopausal women (who have reduce estrogen) lose bone mass at twice the rate as men.
Decreased growth hormone causes bone loss
in both sexes. The physical inactivity & malnutrition (especially
for calcium and Vitamins D & C) of so many elderly also worsens
bone loss. A reduction of one to three inches in height by age 80 is not unusual,
with women shrinking twice as much as men. Young bones have been compared to green tree
branches that can bend considerably before breaking — and upon breaking does so
with splintering. By contrast, old bone is like a dry stick that snaps
upon bending. 20% of hip fractures associated with osteoporosis are
fatal in the US.
Joints in the bones of the inner ear calcify, contributing to
a loss in the ability to hear higher tones. Loss of sweat glands
in the ear causes earwax to become drier & crustier. Wax obstruction
reduces the ability to hear low frequencies.
Aging reduces salivary secretion resulting in a drier mouth and
decreased protection from bacterial infection of the mouth. Gastric
juice volume is reduced 25% by age 60 and there is a 60% decline in
pepsin activity. But this does not noticeably affect digestion except
in the case of heavy meats. Absorption of [Vitamin D](../nutrceut/MiscSupp.html#VitD) (and, hence, calcium
absorption), [Vitamin B12](../nutrceut/MiscSupp.html#B12)
(affected by reduced "intrinsic factor")
and folic acid all typically decline with age.
[(return to contents)](#contents)
### VII. THE FREE RADICAL THEORY OF AGING
Atomic nuclei are surrounded by electron orbitals which contain a
maximum of two electrons, each having opposite spin. Hydrogen has one
outer orbital, but nitrogen, carbon and oxygen have 4 outer orbitals —
with a capacity for 8 electrons (an "octet"). Atoms are most
stable when they have filled orbitals. **Free radicals** are highly
reactive molecules or atoms that have an unpaired electron in an outer
orbital that is not contributing to molecular bonding ("free").
Atoms or small molecules that are free radicals tend to be
the most unstable, because larger molecules can have the capacity to
form resonance structures.
**Electron States of ROS**| Electon States of ROS |
**.** (dot) indicates free-radical extra electron
Normal molecular oxygen (**3O2**, so-called **triplet
oxygen**) is a very unusual free-radical in that it has two unpaired electrons in outer
orbitals (a double radical).
**Pi−bonds** are bonds formed from overlapping p−orbitals. But for
3O2, two
pi−bonds are formed from two p−orbitals, each containing one electron. The two electrons
can have three possible arrangements: two "up"−spin (indicated by two up-arrows
in the diagram), two "down"−spin or one spin "up" and one spin
"down" — which makes 3O2 somewhat
stable. But by the addition of energy (22.5 kcal/mole), both electrons are
move into a single p−orbital, with the electrons having opposite spins
— giving **singlet
oxygen** (**1O2**).
Although singlet oxygen is not a free-radical, the electrons are in an excited state and
can thus cause damaging reactions similar to those caused by oxygen free-radicals.
On the other hand, if an electron
is added to normal triplet oxygen, the new electron completes one orbital, leaving the
other orbital with an unpaired electron — resulting in a **superoxide
anion** (**.**O2**−**), which is a
conventional, unitary free-radical. Singlet oxygen is attracted to double-bonds and can
react destructively with DNA & proteins. Singlet oxygen is especially reactive with the
amino acid histidine — resulting in enzyme denaturation. Singlet oxygen
oxidizes the guanine base of DNA to produce
8−OHdG/8−oxoG [[JOURNAL OF BIOLOGICAL CHEMISTRY; Ravanat,J; 275(51):40601-50604 (2000)](http://www.jbc.org/cgi/content/full/275/51/40601)].
Singlet oxygen from ultraviolet
light is believed to be the major contributor to "photoaging" of the
skin [[JOURNAL OF BIOLOGICAL CHEMISTRY; Berneburg,M; 274(22):15345-15349 (1999)](http://www.jbc.org/cgi/content/full/274/22/15345)].
**Lewis structures** are structural chemical formulas depicting
outer-shell electrons. I use abbreviated Lewis structures showing
only relevant outer-shell electrons to explain free radicals — ie,
I show a single orbital containing paired or unpaired electrons. Because
an orbital containing one (unpaired) electron is not being complemented
with an electron of opposite spin, the electron is said to be in an
"unstable spin state" (another term for "free radical").
Thus, chemicals that react-with and stabilize free radicals are called
**spin-trapping** substances.
Free radicals can damage nucleic
acids, proteins or lipids. For biological systems, oxygen
free radicals are the most important, in particular
**superoxide** (**.**O2**−**),
**nitric oxide** (**.**NO)
and the **hydroxyl radical** (**.**OH).
About 0.3% of superoxide exists in protonated form
(HO2**.**), which is more reactive
than superoxide itself. Because the protenated form of superoxide
is uncharged, it can penetrate cell membranes more effectively
than superoxide. Nitric oxide is a relatively unreactive free-radical
which has a half-life of a few seconds, normally reacting
quickly with oxygen (O2). But if nitric oxide encounters a
superoxide (**.**O2**−**), it forms
peroxynitrite (ONOO**−**) which can decompose to
form a hydroxyl radical (**.**OH). Peroxynitrite, like
the hydroxyl radical, can react directly with proteins and other macromolecules
to produce carbonyls (aldehydes & ketones), cross-linking and lipid
peroxidation. Only 1−4% of the DNA single-strand breaks caused by
peroxynitrite are due to hydroxyl radical (indicating the minor effect decomposition
has on total DNA damage by peroxynitrite) [ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS;
Roussyn,I; 330(1):216-218 (1996)]. Although hydrogen peroxide (H2O2)
and hypochlorite (OCl− — the active ingredient in bleach)
are not themselves free radicals, these oxygen-containing molecules can
facilitate free-radical formation. Moreover, HOCl is estimated to be hundreds of
times more toxic than either hydrogen peroxide or
superoxide [PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Reiter,RJ;
917:376-386 (2000)].
All of these highly reactive oxygen-containing molecules
(including singlet oxygen) are described as
[**Reactive Oxygen Species**](http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/ROS.html) (**ROS**).
ROS attack bases in nucleic acids, amino acid side chains in proteins and double-bonds
in unsaturated fatty acids — with the hydroxyl radical being the strongest
attacker. ROS attack of macromolecules is often called **oxidative stress**.
**Reactive Nitrogen Species** (**RNS**) also cause free radical damage. Peroxynitrite,
which does most of its damage to endothelial cells, is nearly as destructive as
the hydroxyl radical.
In a neutral water solution about one per 10−7 water molecules
will dissociate into two ions, a reaction that can be represented as:
**H:O:H => :OH− + H+**
However, a water molecule subjected to ionizing radiation might dissociate
into two free radicals: a hydroxyl radical & a hydrogen atom. The reaction can be represented as:
**H:O:H => .OH + .H**
A superoxide ion (**.**O2**−**) would result
from the addition of an electron to a normal oxygen
molecule (O2). A more complete Lewis structure of
oxygen-containing free-radical molecules (with oxygen & hydroxide
ion also illustrated for contrast) showing all outer shell electrons would be:
![[ oxygen free-radical molecules ]](radicals.gif)
It would be more accurate to draw resonance structures, but the above
representations may be better for explanatory purposes.
The weed-killing herbicide [paraquat](http://en.wikipedia.org/wiki/Paraquat)
generates superoxide. Superoxide (**.**O2**−**) ions are
generated in large numbers in the mitochondria. Two superoxide ions are enzymatically converted to
hydrogen peroxide (H2O2) by the enzyme superoxide dismutase:
**.O2− +
.O2− + 2H+
=> H2O2 + O2**
The hydroxyl radical (**.**OH) is typically formed by oxidation of a reduced heavy metal
ion (Fe++ or Cu+, usually) by the hydrogen peroxide:
**Fe++ + H2O2
=> Fe+++ + .OH + :OH−**
The last reaction, known as the **Fenton Reaction**, may be the most
dangerous because it can occur in the cell nucleus and lead to DNA damage. The
oxidized iron (Fe+++) can then catalyze the **Haber-Weiss Reaction** between
superoxide and hydrogen peroxide to produce more hydroxyl radicals:
**.O2− + H2O2
=> O2 + .OH + :OH−**
At neutral pH the Haber-Weiss reaction occurs only to a negligible extent
when no metal ion is available to act as a catalyst. In the human body ascorbic acid is
normally beneficial rather than harmful because nearly all iron and copper ions are
tightly bound to carrier proteins (**transferrin** for iron and **cearuloplasmin**
for copper ions), but this is not the case in the Cerebral Spinal Fluid (CSF) or
where there is cellular breakdown due to [ischemic-reperfusion injury](../cryonics/ischemia.html). Bacteria are rich in iron, which
is why hydrogen peroxide from macrophages is such an effective bacterial killer.
Metal ions can also react with ascorbate (Vitamin C) to produce singlet
oxygen (1O2) from normal triplet oxygen (3O2):
**Cu++ + ascorbate +
3O2 => 1O2**
Unlike iron, copper generates more singlet oxygen than hydroxyl radical upon
its reaction with hydrogen peroxide.
Wherever it is produced, the hydroxyl radical is highly reactive and can cause
covalent cross-linking or free-radical propagation in a wide variety of
biological molecules. A cell's superoxide ions tend to be concentrated in the
mitochondria because they are too reactive to travel very far in an unaltered
state — and are much less frequently found in the nucleus than in
the cytoplasm. Similarly, hydroxyl radicals (which have a billionth-of-a-second
half-life) do not drift far from their site of formation. But hydrogen peroxide
molecules are more stable and can drift across the nuclear membrane into
the nucleus or near cell membranes where hydroxyl radicals can be generated when
heavy metal ions are encountered. Hydrogen peroxide can
damage proteins directly by the oxidation of **−SH** groups.
The hydroxyl radical can react with molecules (LH)
in membranes to produce lipid molecule radicals
(**alkyl** = **.L**)
**Peroxyl Radical from Alkyl Radical**| Peroxyl Radical from Alkyl Radical |
**.OH + LH
=> .L + H2O**
These lipid radicals can then react directly with oxygen (autoxidation)
in a self-propagating chain
reaction forming [**lipid peroxides**](http://www.cyberlipid.org/perox/oxid0006.htm) (lipid peroxyl radicals, lipid molecules
containing paired-oxygen groups −−OO−−):
**.L + O2
=> LOO.
LOO. + LH
=> LOOH + .L**
The first reaction is about fifteen hundred times faster with singlet oxygen
(1O2) than with normal triplet oxygen (3O2).
Singlet oxygen is energetic enough, however, that it can react directly with the double
bonds of unsaturated fatty acids, without requiring a free radical intermediate.
The lipid hydroperoxides (LOOH) can promote a Fenton reaction:
**Fe++ + LOOH + H+
=> Fe+++ + .OL + H2O**
The lipid alkoxyl radical
(**alkoxy** = **alkoxyl** = **.OL**) is more reactive
and damaging than the lipid peroxide (peroxyl) radical
(**peroxy** = **peroxyl** = **LOO.**).
Thus, by a small sequence of steps one free-radical (**.L**) has
become two radicals (**.L** and **.OL**) — conditions for an
auto-amplifying chain reaction. Nonetheless, if two alkyl, alkoxyl or peroxyl radical
molecules collide they will nullify each other, but at the cost of creating a
cross-link (covalent bond) between the two lipids.
| | | | | | | | | | | | | | | | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
|
**Free Radical Half-Life at 37ºC**| **Radical** | **Symbol** | **Half-Life Time** |
| **Hydroxyl** | **.OH** | **one nanosecond** |
| **Singlet Oxygen** | **1O2** | **one microsecond** |
| **Superoxide** | **.O2−** | **one microsecond** |
| **Alkoxyl** | **.OL** | **one microsecond** |
| **Peroxyl** | **LOO.** | **ten milliseconds** |
| **Nitric Oxide** | **.NO** | **few seconds** |
|
The reactivity of free radicals can be quantified by a table of half-life
(time taken for half of the remaining radicals to react) values at 37ºC (body
temperature). Short half-life corresponds to high reactivity. The one nanosecond half-life
of the hydroxyl radical indicates that it is so reactive that it reacts with the first
molecule it bumps into.
Outside of the mitochondria, superoxide and hydrogen peroxide can be
generated on the endoplasmic reticulum through oxidation processes involving
cytochrome P−450 and NADPH−cytochrome c reductase. Abnormal
accumulation of normal metabolites such as lactate,
pyruvate, acetoacetyl−CoA and glyceraldehyde−3−phosphate can abnormally
increase levels of NADH oxidase & reduced flavoenzymes such as xanthine
oxidase. In the absence of sufficient electron acceptor substrates these
enzymes can directly transfer electrons to O2 or Fe+++
to form superoxide or Fe++. Ascorbate forms
H2O2 on autoxidation (direct combination with oxygen).
Both ascorbate & **mercaptans** (**thioalcohols**, ie, compounds having
"−SH" groups, where sulfur is substituted for the oxygen of alcohol) are
capable of reducing Fe+++ & Cu++ to Fe++
& Cu+, thereby promoting Fenton reactions.
Lipid peroxidation of polyunsaturated fatty acids exposed to oxygen leads
to rancidity in foods. In living animal cells peroxidized membranes lose
their permeability, becoming rigid, reactive and nonfunctional. Lipid peroxidation
can produce singlet oxygen, hydroperoxides and lipid epoxides. In addition, many
damaging aldehydes are formed during lipid peroxidation, particularly
**M**alon**D**i**A**ldehyde (**MDA**, propanedial)
& **4−H**ydroxy**N**on**E**nal (**4−HNE**). MDA is a
major metabolite of [arachidonic acid (20:4)](../health/essfat.html)[fatty acid with 20−carbons &
4 double-bonds]. MDA assays (notably **TBARS** —
**T**hio**B**arbituric **A**cid-**R**eacting **S**ubstances)
have been widely used as a measure of cell membrane lipid peroxidation.
4−HNE is also a product of **20:4** fatty acid autoxidation. 4−HNE reacts
with cellular components more strongly than MDA. 4−HNE reacts readily
with histidine residues, sulfhydryl groups and primary amino groups of
proteins [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Uchida,K; 89(10):4544-4548 (1992)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC49119/)]. The fact that 4−HNE is
the most toxic known aldehyde produced by lipid peroxidation (much more
toxic than MDA) and yet is practically non-reactive with TBA (about
95% of TDA reactivity is due to MDA) points to the deficiency of
TBARS as a lipid peroxidation assay [ALCOHOL & ALCOHOLISM
20(2):161-173 (1985)]. F2−isoprotanes, produced by
oxidation of arachidonic acid, are the best biomarkers of lipid
peroxidation [[FASEB JOURNAL; Montuschi,P; 18(15):1791-1800 (2004)](http://www.fasebj.org/cgi/content/full/18/15/1791)].
**LIPID PEROXIDATION FORMING MDA**| [ LIPID PEROXIDATION FORMING MDA] |
Unlike free-radicals, the aldehydes MDA, 4−HNE & other aldehydes are rather long-lived
and can drift far from membranes, damaging a wide variety of proteins, lipids & nucleic
acids [FREE RADICAL BIOLOGY AND MEDICINE 11:81-128 (1991)]. Such damaged molecules are
called Advanced Lipid peroxidation End-products (**ALE**, which can be as resistant
to degradation as AGEs [[BRITISH JOURNAL OF PHARMACOLOGY; Negre-Salvayre,A; 153(1):6-20 (2008)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199390/)].
4−HNE inactivates glucose−6−phosphate dehydrogenase, an enzyme required
for the formation of NADPH and for forming ribose residues for nucleic acid
biosynthesis. Aldehyde-bridge formation leads to the protein-protein cross-linking
associated with lipofuscin formation. Plasma levels of both MDA and 4−HNE rise
significantly with age [[FREE RADICAL RESEARCH; Gil,L; 40(5):495-505 (2006)](http://www.ncbi.nlm.nih.gov/pubmed/16551576)].
[Polyunsaturated fatty acids](../health/essfat.html) are more
vulnerable to free radical oxidation than any other macromolecules in the body — and the
sensitivity to free radical damage increases exponentially with the number of double bonds.
Studies of the liver lipids of mammals & a bird (pigeon) show an inverse relationship
between maximum lifespan and number of double bonds [JOURNAL OF GERONTOLOGY
55A(6):B286-B291 (2000)]. Nonetheless, brain phospholipid unsaturation does not vary much
between mammals, probably indicating the importance of unsaturated fatty acids for neural
function [COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY Part B 132:515-527 (2002)].
Animal cells contain three important enzymes to deal with the superoxide
and hydrogen peroxide: **SuperOxide Dismutase** (**SOD**),
**glutathione peroxidase** and **CATalase** (**CAT**). A **dismutase**
is an enzyme that catalyzes the reaction of two identical molecules to produce molecules
in different oxidative states. In the absense of SOD, two superoxide ions can spontaneously
dismutate to produce hydrogen peroxide and singlet oxygen. SOD catalyzes a reaction
between two superoxide ions to produce hydrogen peroxide and triplet oxygen.
**Catalase**
catalyzes the formation of water & free oxygen from hydrogen peroxide.
CAT is present in membrane-limited organelles known as
**peroxisomes**. Peroxisomes contain enzymes that degrade amino
acids & fatty acids — producing hydrogen peroxide as a byproduct.
![[FREE-RADICAL OXIDATION CHAIN]](oxidate.gif)
[Glutathione](../nutrceut/NAC.html)
is a tripeptide composed of the amino acids cysteine,
glycine and glutamic acid. Glutathione is the major antioxidant in the
non-lipid portion of cells (most of the cytoplasm). Glutathione exists in
a reduced form (**GSH**) and an oxidized form (**GSSG**). Reduced
glutathione hydrogen donation can neutralize a hydroxyl radical:
**GSH + .OH
—> .GS + H2O**
and then oxidized glutathione radicals can neutralize each other:
**.GH + .GH
—> GSSG**
**Glutathione peroxidase**
neutralizes hydrogen peroxide by taking hydrogens from two GSH molecules — resulting in
two H2O and one GSSG.
The enzyme **glutathione reductase** then
regenerates GSH from GSSG with NADPH as a source of hydrogen.
The elimination of hydrogen peroxide by glutathione can be written as
the reaction:
**2 GSH + H2O2
=> GSSG + 2 H2O**
Long-lived transgenic fruit flies in which the enzyme which synthesizes GSH
was overexpressed showed a maximum lifespan extension of nearly
50% [[JOURNAL OF BIOLOGICAL CHEMISTRY; Orr,WC; 280(45):37331-37338 (2005)](http://www.jbc.org/cgi/content/full/280/45/37331)].
Glutathione levels generally decline with age [JOURNAL OF ANTI-AGING MEDICINE; Lang,CA;
4(2):137-144 (2001)], although no reduction of serum glutathione was seen in
elderly women deemed to be in excellent physical and mental
health [[JOURNAL OF LABORATORY AND CLINICAL MEDICINE; Lang,CA; 140(6):413-417 (2002)](http://www.ncbi.nlm.nih.gov/pubmed/12486409)].
Free radicals act on lipids to
produce peroxides (−O−O− bonds) resulting in mutagenic epoxides and
insoluble & non-digestible age pigments such as lipofuscin. Glutathione
peroxidase/glutathione destroys fat peroxides in the same way it eliminates hydrogen peroxide:
**2 GSH + ROOH
=> GSSG + ROH + H2O**
**Superoxide dismutase**(**SOD**) is the most abundant
anti-oxidant enzyme in animals. The liver, in particular, is very high
in SOD. Cellular concentration of SOD relative to metabolic
activity is a very good lifespan predictor of animal species. Most mammals
experience a lifetime energy expenditure of 200,000 calories per gram,
but humans have an amazing 800,000 calories per gram. Humans have the
highest levels of SOD — relative to metabolic rate — of all species studied.
Oxidative damage to DNA is ten times greater in rats than in humans.
Maximum lifespan correlates with lower rate of free-radical production
and higher rate of DNA repair [JOURNAL OF COMPARATIVE PHYSIOLOGY B
168(3):149-158 (1998)].
The SOD molecule in the cytoplasm ([SOD1](http://en.wikipedia.org/wiki/SOD1)) and outside of cells ([SOD3](http://en.wikipedia.org/wiki/SOD3)) contains copper & zinc atoms
(**Cu/Zn−SOD**), whereas the SOD in mitochondria
([SOD2](http://en.wikipedia.org/wiki/SOD2))
contains manganese (**Mn−SOD**).
Superoxide dismutase without glutathione peroxidase or catalase (CAT) to
remove hydrogen peroxide is of little value. Insects lack glutathione
peroxidase, but experiments have been performed on fruit flies made transgenic
by having extra genes for SOD, CAT or both. The flies that were given
extra genes for SOD or CAT (but not both) had no more than a 10%
increase in mean lifespan, with no increase in maximum lifespan. But flies
that had extra genes for both SOD ***and*** CAT showed maximum
lifespan increase by as much as a third, while showing less protein oxidative
damage and better physical performance [SCIENCE 263:1128-1130 (1994)].
But criticisms that the above experiments had been performed on short-lived
strains of flies led to later experiments on long-lived strains of flies which
showed no lifespan extension for overexpression of Cu/Zn−SOD,
Mn−SOD, catalase and
thioredoxin [[JOURNAL OF BIOLOGICAL CHEMISTRY; Orr,WC; 278(29):26418-26422
(2003)](http://www.jbc.org/cgi/content/full/278/29/26418)].
Nonetheless, an experiment using SOD/CAT mimetics in nematode worms increased
mean lifespan 44% [SCIENCE 289:1567-1569 (2000)]. Selective
inbreeding of bread-mold fungus resulted in strains with lifespans more
than 6 times longer than wild-type — a change that was shown to be due
to increased expression of antioxidant enzymes [FREE RADICAL BIOLOGY &
MEDICINE 8:355-361 (1990)]. Females express both more Mn−SOD and more
glutathione peroxidase than males, and this has been suggested to be the
reason females live longer than males in mammalian species [FEBS LETTERS;
Vina,J; 579(12):2541-2545 (2005)]. The maximum lifespan of transgenic mice has been
extended about 20% by overexpression of human catalase targeted to
mitochondria [SCIENCE; Schriner,SE; 308:1909-1911 (2005)]. Although
[naked mole rats](http://en.wikipedia.org/wiki/Naked_mole_rat)
exhibit high levels of oxidative damage, these levels remain unchanged for over two
decades [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Perez,VI; 106(9):3059-3064 (2009)](http://www.pnas.org/content/106/9/3059.long)].
Radiation produces the hydroxyl radical, but most of the oxygen
free radicals are byproducts of cell metabolism — particularly in the
mitochondria, the lysosomes and the peroxisomes. One of the reasons
these organelles are surrounded by membranes may be to protect the cell from
the free-radicals they generate. DNA may be sequestered in the nucleus,
in part, as additional protection against free radicals. Nonetheless, free
radicals contribute to DNA damage and mutation.
In addition to enzymes, the animal cell uses many other chemicals to protect against
oxygen free-radicals. [Vitamin E](../nutrceut/VitaminE.html)
is the main free-radical trap in the (lipid) membranes. **Vitamin C** acts as an
anti-oxidant in the non-lipid ("watery") portions of cells, between cells and
in the bloodstream. [Melatonin](../nutrceut/melatonin.html),
a hormone produced by the pineal gland in decreasing quantities with aging, efficiently
crosses membranes (including the nucleus) and is effective against hydroxyl radicals.
**Uric acid** (which is mostly formed from purine degradation) protects
Vitamin C from oxidation by divalent ions and can act as an anti-oxidant.
Uric acid also protects against free-radical catalysis by binding iron. Humans have
higher levels of uric acid than monkeys and other mammals because humans lack the enzyme
uricase. But birds typically have twice the plasma uric acid concentration as humans. Birds
often live several times as long as comparably sized mammals despite over twice the metabolic
rate, 2−6 times the plasma glucose and a 3ºC higher body temperature.
Mammals fed anti-oxidants show up to a 30% increase in average lifespan,
but no increase in maximum lifespan. Anti-oxidants are most valuable for
animals that are cancer-prone, or subjected to radiation or chemical toxins.
There are evidently homeostatic mechanisms in cells that govern the amount
of allowable anti-oxidant activity. For example, increased levels of
Vitamin E in the diet correlates with reduced levels of glutathione
peroxidase activity, and vice versa. Vitamin E was shown to increase
catalase in banana fruit-flies — with increasing doses of Vitamin E
extending fruit-fly lifespan up to a dose of 5 micrograms/mL, above which
increasing doses decreased lifespan [GERONTOLOGY 42:312-321 (1996)].
(For more on anti-oxidants and anti-oxidant enzymes, see my essay
[General Anti-Oxidant Actions](../nutrceut/AntiOxidants.html).)
[(return to contents)](#contents)
### VIII. MITOCHONDRIA AND AGING
**Mitochondrion organelle**| Mitochondrion organelle |
The **mitochondria** are capsule-shaped cellular organelles that generate energy
([ATP molecules](http://en.wikipedia.org/wiki/Adenosine_triphosphate))
from aerobic (oxygen-utilizing) metabolism utilizing
respiratory chain and ATP synthase enzymes. Most animal cells contain between
a few hundred and a few thousand mitochondria. The most mitochondria are found in
the cells that are most metabolically active: neurons and muscle cells, where
mitochondria make up about 40% of cell volume. About 10% of the body
weight of a human adult is mitochondria.
A mitochondrion has two membranes. The outer membrane contains small pores
([porins](http://en.wikipedia.org/wiki/Porin_%28protein%29), also
known as Voltage-Dependent Anion Channels,**VDACs**)
that are freely permeable to ions and other molecules smaller than
10 [kiloDaltons](http://en.wikipedia.org/wiki/Dalton_%28unit%29)
in size. The inner membrane is highly impermeable, even to
[protons](http://en.wikipedia.org/wiki/Proton) (H+
ions). The proton gradient across the inner membrane is used by
[ATP synthetase](http://en.wikipedia.org/wiki/ATP_synthase)
enzyme to generate ATP molecules. The region between
the outer membrane and the inner membrane is more positively charged
(**P−phase**) because of the higher proton concentration, whereas the
inside of the inner membrane is more negatively charged (**N−phase**, the
[matrix](http://en.wikipedia.org/wiki/Matrix_%28biology%29#Mitochondrial_matrix)). It is in the matrix that the
[Krebs citric acid cycle](http://en.wikipedia.org/wiki/_acid_cycle)
occurs. There can be tens of thousands of respiratory chain and associated ATP synthase
molecules embedded in the inner membrane of a mitochondrion, especially in
metabolically active cells that have their inner membranes most highly folded into
[cristae](http://en.wikipedia.org/wiki/Crista)
that increase surface area.
The inner membrane contains a number of active molecule carriers, including a
phosphate (**Pi** = H2PO4-)
carrier and the **Adenine Nucleotide Transporter** (ANT). The ANT imports
ADP molecules into the matrix for ATP synthesis in exchange for ATP molecules which
are exported for energy use throughout the cell (like portable batteries). The
**respiratory chain** ("electron transport chain") attached to
the inner wall of the inner membrane is composed of 4 protein complexes.
These protein complexes are identified as **Complex I, II, III and IV**.
Complex II consists of only four peptides, two of which comprise the Krebs citric
acid cycle protein
[succinate dehydrogenase](http://en.wikipedia.org/wiki/Succinate_-_coenzyme_Q_reductase),
and two of which anchor the complex to the inner mitochondrial membrane.
Complex I and Complex II independently supply electrons to Complex III,
which supplies electrons to Complex IV. Soluble carriers are used to transport
electrons to and from Complex III. The soluble carrier transporting electrons
from Complex I & II to Complex III is
[**Coenzyme Q**](../nutrceut/CoEnzymeQ.html)
(CoQ). The soluble carrier that transports electrons from Complex III to Complex IV is
[**cytochrome−c**](http://en.wikipedia.org/wiki/Cytochrome_C).
For this reason Complex III is also known as
**cytochrome−c reductase** and Complex IV is also known as
**cytochrome−c oxidase**. Complex IV combines its electrons
(which are actually hydrogen atoms) with oxygen to form water. The energy released
by the oxidations in the respiratory chain are used to pump protons outside the
inner mitochondrial membrane.
**Protons pumped out of mitochondrial matrix**| Protons pumped out of mitochondrial matrix |
**Re-entering protons drive "ATP turbine"**
The inner mitochondrial membrane is fairly impermeable to H+ ions
("protons") and thus is able to function much like a hydroelectric dam.
Respiratory enzymes (Complex I, III & IV) pump protons out of the inner mitochondrial
matrix, building proton pressure outside the "dam" (the membrane). The proton
pressure ("proton-motive force") across the inner membrane is composed of two components:
a pH difference and an electrical potential (membrane potential), which is the
most important component. The pH difference is small, amounting to only about 0.5 pH
units. The [membrane potential](../cryonics/viable.html#potential)
of the mitochondrial membrane is about twice as great as that of a large nerve fiber, amounting
to over 200 milliVolts. **Complex V** (F0F1−ATP synthase)
is the "hydroelectric turbine" that utilizes the energy of the proton flow into the
matrix through the "turbine" to synthesize ATP. The ATP synthase (Complex V)
"rotary motor" is the smallest known natural nanomachine. It uses proton-motive
force to drive the endothermic reaction:
**ADP + Pi => ATP**
The combined result of respiratory (oxidative) steps and the ATP-creation (phosphorylation of
ADP) step is called **oxidative phosphorylation**. Normally respiration (oxygen consumption)
and phosphorylation (ATP production) are tightly **coupled**, ie, the amount of ATP
produced corresponds to the amount of oxygen consumed — referred to as **state 3
respiration**. In the absence of ADP (eg, in a resting state), however, any respiration
that occurs will be due to "proton leak" through the inner mitochondrial membrane
rather than due to ATP production — referred to as **state 4 respiration**.
(State 1, state 2 and state 5 are experimental conditions of more
historical interest than metabolic interest.)
In state 4 respiration protons flowing directly through the inner membrane rather
than through the "ATP turbine" (Complex V) produce heat energy rather than ATP
energy. **Uncoupling proteins** are weak acids that dissolve inner membrane lipids thereby
increasing the uncoupling of oxidation from phosphorylation. Uncoupling respiration from phosphorylation
to produce heat is useful for small rodents, naked newborn babies, and hibernating &
cold-acclimated animals, all of which contain "brown fat". Uncoupling is also useful
for fever production. **UCP1** is the UnCoupling Protein found in "brown fat",
fat which has been made brown by high concentrations of mitochondria. **UCP2** has broad tissue
distribution and seems to function in stress response, but its expression is less than 1%
of UCP1. **UCP3** is found in muscle and is regulated by thyroid hormone (T3).
UCP2 & UCP3 may cause uncoupling for the purpose of reducing mitochondrial superoxide
production [[FREE RADICAL BIOLOGY & MEDICINE; Echtay,KS; 43(10):1351-1371 (2007)](http://www.ncbi.nlm.nih.gov/pubmed/1793618)].
The function of UCP1 is to generate
heat ("thermogenesis"). Claims have been made that UCP3 generates little
heat, but functions to reduce free radical damage by lowering protein gratient during
periods of high metabolic activity. Mice with higher UCP3 have shown higher metabolic
intensity (17% greater resting oxygen consumption) and 36% longer
lifespan [AGING CELL; Speakman,JR; 3(3):87-95 (2004)]. Proton leak has not been
shown to be a factor in CRAN ([Caloric
Restriction with Adequate
Nutrition](../calories/calories.html)) [[AMERICIAN JOURNAL OF PHYSIOLOGY; Ramsey,JJ; 286(1):E31-E40 (2004)](http://ajpendo.physiology.org/cgi/content/full/286/1/E31)].
The fact that dieting-resistant obese subjects have been shown to have smaller amounts of
UCP3 [[DIABETES; Harper,M; 51(8):2459-2466 (2002)](http://diabetes.diabetesjournals.org/cgi/content/full/51/8/2459)] would seem to indicate that
thermogenesis from UCP3 is not negligible.
Compared to the heart & brain, mitochondria in the liver are more tightly coupled
and use oxygen more efficiently for ATP production. The heart & brain mitochondria
use more oxygen than liver mitochondria, but can produce ATP faster. Brain mitochondria
are more geared toward maintaining cell integrity, in contrast to heart mitochondria
which are more geared toward preserving cellular energy
state [[AMERICAN JOURNAL OF PHYSIOLOGY; Cairns,CB; 274(5):R1376-R1383 (1998)](http://ajpregu.physiology.org/cgi/content/full/274/5/R1376)].
Increasing insulin levels
associated with aging and type−2 diabetes stimulates nitric oxide synthetase resulting
in [peroxynitrite](#radical) [THE INTERNATIONAL JOURNAL
OF BIOCHEMISTRY & CELL BIOLOGY 34:1340-1354 (2002)]. Lipid peroxidation of the inner
mitochondrial membrane by peroxynitrite can increase proton leak independent of uncoupling
protein. Peroxynitrite can also degrade function of respiratory enzymes [JOURNAL OF
NEUROCHEMISTRY 70:2195-2202 (1998)] and inactivate mitochondrial superoxide dismutase (Mn−SOD)
enzyme [PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA) 93(21):11853-11858 (1996)].
Mitochondria are the only
cellular organelles with their own DNA. (There is no other cellular DNA
outside the nucleus apart from the DNA of mitochondria.) Mitochondrial DNA
(**mtDNA**) in humans are circular strands of 16,569 nucleic acids that
code for 37 genes — 22 transfer RNAs, 2 ribosomal RNAs and 13 transmembrane
proteins. There are nearly 1,500 other gene products in mitochondria, which are
coded-for by nuclear DNA (**nDNA**). In contrast to nDNA, the mtDNA is
derived almost entirely from the mother. Each cell contains many mitochondria, but the total
mtDNA in a cell represents less than 1% of the amount of DNA found in the nucleus.
**Inner Membrane mtDNA-coded Proteins in Complex I, III, IV & V**| Inner Membrane mtDNA-coded Proteins in Complex I, III, IV & V |
**Re-entering protons drive "ATP turbine"**
Each mitochondrion contains 2-to-12 identical copies of mitochondrial DNA
(2-to-12 circular strands).
Each mtDNA strand codes for 13 proteins, all of which are transmembrane subunits
of Complex I, III, IV or V. Of the 13 mtDNA proteins, 7 are in Complex I,
1 is in Complex III, 3 are in Complex IV and 2 are in Complex V.
A distinctive feature of the 13 proteins
coded-for by the mtDNA is that they are hydrophobic (not easily dissolved
in water), suggesting that it might be difficult to synthesize &
transport them in the watery cytoplasm. For this reason it has seemed improbable
that the mtDNA for these proteins could be moved to the nucleus where they
would be better protected & repaired. But one of the Complex V (ATPase)
mtDNA-coded proteins has been successfully synthesized in the nucleus and
utilized in the mitochondria for a mammalian cell [REJUVENATION RESEARCH;
Zullo,SJ; 8(1):18-28 (2005)] giving hope to the idea that all 13 mtDNA
proteins might eventually be moved to the nucleus. An alternate hypothesis, however,
claims that the mtDNA genes are of value in providing rapid local synthesis of proteins
required for oxidative phosphorylation. Oxidative stress due to insufficient oxidative
phosphorylation capability could signal mitochondrial transcription factors to induce
production of mtDNA-coded proteins that are then implanted into the inner membrane where
they attract the nDNA-coded proteins required for complete assembly of the
complexes [PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY; Allen,JF;
358(1429):19-38 (2003)].
Complex I, which has 7 mtDNA-coded proteins (more than a quarter of
all the proteins in the Complex), ages most rapidly. Substantia nigra neurons have increased
susceptibility to Complex I defects — which may be responsible for Parkinson's
Disease [NEUROBIOLOGY OF AGING; Smigrodzki,R; 25:1273-1281 (2004)].
By contrast, Complex II (which has no mtDNA-coded proteins) and Complex III
(which has only one) are relatively unaffected by aging. Cytochrome−c oxidase (between
Complex III and Complex IV) activity declines with age, resulting in increased production
of superoxide and hydrogen peroxide. Diseases due to mutated mtDNA have the greatest
effect on cells producing the most energy — cells of brain and muscle — hence
mitochondrial diseases are often **encephalomyopathies** . A very common syndrome
of mitochondrial disease is **M**itochondria **E**ncephalomyopathy, **L**actic
**A**cidosis & **S**troke (**MELAS**). **Homoplasmy** describes the
original condition of all of a person's mtDNA being the same, but as mtDNA mutations occur
and the mutated mtDNA replicates, cells, tissues and even mitochondria can have a
mixture of mtDNA types, a condition known as **heteroplasmy**.
An estimated 1−2% of oxygen used by mitochondria will normally "leak"
from the respiratory chain to form superoxide [JOURNAL OF NEUROCHEMISTRY
59:1609-1623 (1992) & JOURNAL OF INTERNAL MEDICINE 238:405-421 (1995)]. The pro-inflammatory
cytokine **Tumor Necrosis Factor−alpha** (**TNF−α**, associated with
[the metabolic syndrome](../health/MacroNut.html#syndrome))
induces increased free radical production from the respiratory
chain [[AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY; Corda,S;
24(6):762-768 (2001)](http://www.nlm.nih.gov/medlineplus/print/ency/article/003646.htm)]. Aging is associated with decreased oxidative phosphorylation
coupling efficiency and increased superoxide production. Free radicals can damage the
mitochondrial inner membrane, creating a positive feedback-loop for increased
free-radical creation. The "viscious cycle" theory that free radical damage
to mitochondrial DNA leads to mitochondria that produce more superoxide has been
questioned. The most damaged mitochondria are consumed by lysosomes whereas the more
defective mitochondria (which produce less ATP as well as less superoxide) remain to
reproduce themselves [REJUVENATION RESEARCH; de Grey,A; 8(1):13-17 (2005)]. But the
efficiency of lysosomes to consume malfunctioning mitochondria declines with age,
resulting in more mitochondria producing higher levels of superoxide. Mitochondria of
older organisms are fewer in number, larger in size and less efficient (produce less
energy & more superoxide).
[**Coenzyme Q**](../nutrceut/CoEnzymeQ.html)
(CoQ, in humans CoQ10) is also known as **ubiquinone**,
so-called because it is "ubiquitous" (universally-found) in almost
all cellular organisms, with the exception of gram-positive bacteria and some
fungi. CoQ is an essential component of the mitochondrial respiratory chain.
From Complex I or Complex II dehydrogenase CoQ is reduced to
CoQH2 and subsequently oxidized in two steps — first to
**.**CoQ**−** and then to CoQ. But
**.**CoQ**−** is unstable and can easily errantly
transfer an electron to an O2 molecule resulting in superoxide
ion (**.**O2−).
**.O2− from Complex III escapes Mitochondria**| <SUP>.</SUP>O<SUB>2</SUB><SUP>−</SUP>from Complex III escapes Mitochondria |
Complex I has been believed to generate **.**O2−
in one of the iron-sulfur clusters, which would go to the mitochondrial matrix
where it could be neutralized by Mn−SOD. Experiments on isolated mitochondria identified the
site of superoxide generation to be at the flavine mononucleotide moiety of
Complex I [[JOURNAL OF BIOLOGICAL CHEMISTRY; Kudin,AP; 279(6):4127-4135 (2004)](http://www.jbc.org/cgi/content/full/279/6/4127)],
but claims have been made that experiments on isolated mitochondria are
misleading [[ACTA BIOCHEMICA POLONICA; Nohl,H; 51(1):223-229 (2004)](http://www.actabp.pl/pdf/1_2004/223.pdf)]. An experiment on
isolated synaptosomes indicated that Complex I inhibition
increases H2O2
production [[THE JOURNAL OF NEUROSCIENCE; Tretter,L; 24(36):7771-7778 (2004)](http://www.jneurosci.org/cgi/content/full/24/36/7771)]. Most of the
**.**O2− generated from Complex III comes from
**.**CoQ**−**, with about half going to the matrix to be neutralized
and half floating toward the
cytoplasm [[JOURNAL OF BIOLOGICAL CHEMISTRY; Muller,FL; 279(47):49064-49073 (2004)](http://www.jbc.org/cgi/content/full/279/47/49064)]. Thus,
**.**O2− from Complex I & III can cause
lipid peroxidation of the inner mitochondrial membrane and mtDNA damage, whereas
**.**O2− from Complex III can damage the whole
cell, including nDNA. Membrane potentials below 140 mV (potential
resulting from the proton gradients across the inner mitochondrial membrane) are not
associated with **.**O2**−**, but
above 140 mV **.**O2**−** generation
increases exponentially with potential. Uncoupling proteins can be a device
for reducing proton pressure (membrane potential), thereby reducing superoxide production.
**Voltage drops between Complexes**| Voltage drops between Complexes |
Higher voltage drops between energy states in the Complexes also result in greater
capacity for superoxide generation. This may account for the high superoxide production
associated with Complex I, which has a high voltage drop in transferring its
electrons to Complex III.
Oxidative damage to particular mitochondrial proteins in the flight muscles of houseflies
has been identified as a [biomarker of aging](#biomarkers) for
those insects. Specifically, adenine nucleotide transferase enzyme in mitochondrial
membranes [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Yan,L;
95(22):12896-12901 (1998)](http://www.pnas.org/cgi/content/full/95/22/12896)] and the
[citric
acid cycle](http://en.wikipedia.org/wiki/_acid_cycle) enzyme
aconitase [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Yan,L;
94(21):11168-11172 (1997)](http://www.pnas.org/cgi/content/full/94/21/11168)] are particularly vulnerable to oxidative damage and are
used to identify the "physiological age" of houseflies. Aconitase also shows
the most significant age-related decline of any citric acid cycle enzyme in
mice [[MECHANISMS OF AGING AND DEVELOPMENT; Yarian,CS; 127(1):79-84
(2006)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835517/)]. Aconitase is readily oxidized by superoxide, a process that generates
hydroxyl radical [[JOURNAL OF BIOLOGICAL CHEMISTRY; Vasquez-Vivar,J;
275(19):14064-14069 (2000)](http://www.jbc.org/cgi/content/full/275/19/14064)].
CoQ forms an important part of the antioxidant defense against these
superoxide radicals [BIOCHEMISTRY AND CELL BIOLOGY 70:390-403 (1992)].
The Mn−SOD (SuperOxide Dismutase) of mitochondria can be induced to higher
concentrations by oxidative stress (in contrast to the cytoplasmic
Cu/Zn−SOD which is constitutive rather than induced). Heart mitochondria
also contains catalase (which is confined to peroxisomes in most other
tissues) [BIOSCIENCE REPORTS 17(1):3-8 (1997)].
Associated with aging is a decline in the amount of CoQ in organs.
A person 80 years old will typically have about half as much CoQ10 in the
heart, lungs and spleen as a 20-year-old [LIPIDS 24(7):579-584 (1989)].
Declines in functional mitochondria &
CoQ10 with age is most damaging to those organs that have the highest energy
demands per gram of tissue, namely: the heart, kidney, brain, liver and
skeletal muscle, in that order [JOURNAL OF INTERNAL MEDICINE 238:405-421
(1995)]. Neurons are the largest cells in the body and have the highest
metabolic demands, with 70% of ATP produced required to maintain the
sodium-potassium pump. Clinically, damage to brain and muscle tissue
are the first symptoms of mitochondrial disease. Mitochondria in the brain
tissue of
[Alzheimer's Disease](../lifeext/Alzheimer.html)
patients is particularly damaged. Therapy has included the B−vitamins that
act as coenzymes in the respiratory chain (thiamine, riboflavin, niacinamide)
and CoQ10 [ACTA NEUROLOGICA SCANDINAVIA 92:273-280 (1995)].
mtDNA deletion mutations accumulate in post-mitotic cells with
age [BIOCHIMICA ET BIOPHYSICA ACTA 410:183-193 (1999)].
The "**mitochondrial theory of aging**" postulates that damage
to mtDNA and organelles by free radicals leads to loss of mitochondrial
function and loss of cellular energy (with loss of cellular function).
Mutations in mtDNA occur at 10-20 times the rate seen in nuclear DNA. A
significant portion of "photoaging" of the skin may be due to
mtDNA deletions from singlet oxygen induced by ultraviolet
light [[JOURNAL OF BIOLOGICAL CHEMISTRY; Berneburg,M; 274(22):15345-15349
(1999)](http://www.jbc.org/cgi/content/full/274/22/15345)]. Transgenic mice having high levels of mtDNA point mutations and
deletions are models of accelerated
aging [[CELL METABOLISM; Edgar,D; 10(2):131-138 (2009)](http://www.ncbi.nlm.nih.gov/pubmed/19656491) and
[AGING; Edgar,D; 1(12):1028-1032 (2009)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815752/)]. Unlike
nuclear DNA, mtDNA has no protective histone proteins. And DNA repair is less
efficient in mitochondria than in the nucleus. These factors account for the
more rapid aging seen with Complex I & III as compared to
Complex II & IV. Aging mitochondria become enlarged and, if they
can be engulfed by lysosomes, are resistant to degredation and contribute to
lipofuscin formation [[EUROPEAN JOURNAL OF BIOCHEMISTRY; Brunk,UT; 269(8):1996-2002 (2002)](http://content.febsjournal.org/cgi/content/full/269/8/1996)].
A comparison of
7 non-primate mammals (mouse, hamster, rat, guinea-pig, rabbit, pig and
cow) showed that the rate of mitochondrial superoxide and hydrogen peroxide
production in heart & kidney were inversely correlated with maximum life
span [FREE RADICAL BIOLOGY & MEDICINE 15:621-627 (1993)]. A similar study
of 8 non-primate mammals showed a direct correlation between maximum lifespan
and oxidative damage to mtDNA in heart & brain. There was a 4-fold
difference in levels of oxidative damage and a 13-fold difference in
longevity, supportive of the idea that mtDNA oxidative damage is but one
of several causes of
aging [[THE FASEB JOURNAL; Barja,G; 14(2):312-318 (2000)](http://www.fasebj.org/cgi/content/full/14/2/312)].
A comparison of the heart mitochondria in rats (4-year lifespan) and
pigeons (35-year lifespan) showed that pigeon mitochondria leak fewer
free-radicals than rat mitochondria, despite the fact that both animals have
similar metabolic rate and cardiac output. Pigeon heart mitochondria
(Complexes I & III) showed a 4.6% free radical
leak compared to a 16% free radical leak in rat heart mitochondria
[MECHANISMS OF AGING AND DEVELOPMENT 98(2):95-111 (1997)]. Hummingbirds
use thousands of calories in a day (more than most humans) and have
relatively long lifespans (the broad-tailed hummingbird *Selasphorus
platycerus* has a maximum lifespan in excess of 8 years). Birds have
less unsaturation (oxidizability) in their mitochondrial membranes and
have higher levels of small-molecule antioxidants, such as ascorbate
& uric acid. Even for mammals there is a direct relationship between mitochondrial
membrane saturation and maximum
lifespan [JOURNAL OF LIPID RESEARCH; Pamplona,R; 39(10):1989-1994 (1998)].
Free-radicals from mitochondria result in damage to cellular protein,
lipids and DNA throughout the cell. This damage has been implicated as a
cause of aging. If the fatty acids entering the mitochondria for
energy-yielding oxidation have been peroxidized in the blood, this places
an additional burden on antioxidant defenses.
The greatest damage occurs in the mitochondria themselves,
including damage to the respiratory chain protein complexes (leading to higher
levels of superoxide production), damage to the mitochondrial membrane
(leading to membrane leakage of calcium ions and other substances) and
damage to mitochondrial DNA (leading to further damage to mitochondrial protein
complexes). An experiment in yeast that improved the accuracy of mitochondrial
protein synthesis demonstrated a 27% longer mean life
span [JOURNAL OF GERONTOLOGY 57A(1):B29-B36 (2002)].
**Mitochronrial Permaeability
Transition Port (MPTP)**| Mitochronrial Permaeability <br> Transition Port (MPTP)</ |
Mitochondria play a key role in **apoptosis** ("cell suicide").
Release of cytochrome−c from mitochondria into the cytoplasm is the
event which initiates apoptotic cell destruction by caspase enzymes. Release
of cytochrome−c into the cytoplasm can occur either by a
Ca2+−dependent mechanism or a Ca2+−independent
mechanism. In the **Ca2+−dependent case** Ca2+
overload in the mitochondrion triggers opening of the Mitochondrial Permeability
Transition Pore (**MPTP**), which penetrates both the outer and
inner membranes making a channel between the mitochondrial matrix and the
cytosol outside the mitochondrion. The MPTP is a complex consisting of three
proteins, **VDAC** (porin) of the outer membrane, **ANT** (Adenine Nucleotide
Translocator) of the inner membrane and cyclophilin−D.
**Cyclophilin−D** protein binds to ANT to promote MPTP
formation [[BIOCHEMICAL JOURNAL; Li,Y; 383(Pt 1):101-109 (2004)](http://www.biochemj.org/bj/383/0101/bj3830101.htm)], possibly
by increasing the sensitivity of the MPTP components to the effects of
Ca2+ [[CIRCULATION RESEARCH; Weiss,JN; 93(4):292-301 (2003)](http://circres.ahajournals.org/cgi/content/full/93/4/292)].
The entry of large solutes and accompanying water into the
matrix causes the mitochondrion to swell and burst, releasing cytochrome−c
into the cytoplasm.
The **Ca2+−independent case** requires two
separate events for cytochrome−c release: (1) formation of large
pores in the outer mitochondrial membrane by **Bax/Bak** proteins and (2) release
of cytochrome−c from the inner mitochondrial
membrane [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Ott,M; 99(3):1259-1263 (2002)](http://www.pnas.org/cgi/content/full/99/3/1259)]. The Ca2+−independent case
can lead to
[apoptosis](http://en.wikipedia.org/wiki/Apoptosis),
whereas the Ca2+−dependent case is invariably associated with
[necrosis](http://en.wikipedia.org/wiki/Necrosis).
In apoptosis the MPTP opens only briefly (if it opens at all), whereas in necrosis
the MPTP remains open. Apoptosis requires ATP energy, but ATP energy is depleted
if the MPTP remains open [NATURE; Halestrap,A; 434:578-579 (2005)]. The threshold
amount of Ca2+ which causes MPTP opening in lymphocytes, brain and liver
of old mice is significantly lower than that of young mice [BIOCHEMICAL AND
BIOPHYSICAL RESEARCH COMMUNICATIONS; Mather,M; 273(2):603-608 (2000)].
[CoEnzyme Q10](../nutrceut/CoEnzymeQ.html)
has been shown to reduce apoptosis
by direct inhibition of the MPTP [[JOURNAL OF BIOLOGICAL CHEMISTRY; Papucci,L; 278(30):28220-28228 (2003)](http://www.jbc.org/cgi/content/full/278/30/28220)].
**Cardiolipin**| Cardiolipin |
Cytochrome−c is normally held to the inner mitochondrial membrane by the
lipid **cardiolipin** (diphosphatidylglycerol). Cardiolipin composes 10% of
the inner mitochondrial membrane and is present at lower concentrations in the
outer mitochondrial membrane (especially near contact sites between the
two membranes). This distinctive lipid is found only in mitochondrial
membranes. Mitochondrial membrane cardiolipin content declines with age, resulting
in a decline in cytochrome−c activity. 40% lower cardiolipin content and
35% lower cytochrome−c activity has been demonstrated in old rats
compared to young rats. Restoration of membrane cardiolipin content restored
cytochrome−c activity [FEBS LETTERS; Paradies,G; 406(1-2):136-138
(1997)].
Oxidation of cardiolipin releases cytochrome−c from the
inner mitochondrial membrane, but cytochrome−c will not be released into
the cytoplasm to induce apoptosis without the formation of large pores in the
outer mitochondrial membrane by **Bax/Bak** protein. **Bax/Bak** membrane
permeabilization occurs preferentially at cardiolipin-rich contact sites between
the outer and inner mitochondrial
membrane [[BMC CELL BIOLOGY; Lutter,M; 2:22-30 (2001)](http://www.biomedcentral.com/content/pdf/1471-2121-2-22.pdf)]. But **Bax/Bak**
permeabilization of the outer membrane alone may be sufficient to induce apoptosis.
If only one or a few mitochondria
release cytochrome−c apoptosis may not occur, but the damaged mitochondria
would themselves be degraded. By this means a few aberrant mitochondria which
are producing excessive free radicals can be eliminated.
(For more about mechanisms of **apoptosis** see
[Cellular Senescence and Apoptosis in Aging](#senescence))
[(return to contents)](#contents)
### IX. THE GLYCATION THEORY OF AGING
**Proteins** are long chains of amino acids
(amino acid polymers, or polypeptides). 20 different amino acids occur in
animal proteins. Amino acids are all organic compounds
with a protonated **amino**
group [−NH3**+**] and an ionized **carboxyl**
group [−COO**−**] attached to the same
(alpha-position) carbon atom.
![[AMINO ACIDS]](amino.gif)
![[THE PEPTIDE BOND]](peptide.gif)
Linkage of the carboxyl group of one amino
acid with the amino group of another amino acid (and the loss of a water
molecule) is the basis of the **peptide bond**. Peptide bonds are
formed on cell ribosomes during protein synthesis.
Proteins can be damaged both by free-radicals and by glycation.
**Glycation** (also called the **Maillard reaction**, or
**non-enzymatic glycosylation**) is a reaction by which **reducing sugars** become
attached to proteins without the assistance of an enzyme. (For details on the properties
of reducing sugars, see [cryopreservation with sugars](../cryonics/vitrify.html#sugars).)
This attachment
occurs at the free amine group of lysine or arginine, which is not involved
in the peptide bond. The reaction between glucose and a lysine amino acid
in a protein molecule can be represented as follows:
![[glycation/oxidation
reactions form AGEs ]](amadori.gif)
In the diagram, glycation is the formation of a double-bond between the
glucose aldehyde-group and the lysine amino group with the elimination of
a water molecule. The double-bond between the glucose carbon and the lysine
nitrogen is an **imine** (also known as a **Schiff base**).
The imine can quickly re-arrange atoms such that the 2-carbon (2nd carbon)
of the glucose loses its two hydrogens — resulting in a **carbonyl
group** (>C=O) and in hydrogen-saturation of the carbon & nitrogen which
formerly constituted the imine. This re-arrangement structure is called an
**Amadori product** (a ketoamine). Both glycation and Amadori product
formation are completely reversible reactions. But the formation of
**Advanced Glycation End-products** (**AGEs**) by oxidation of
Amadori products is irreversible.
AGEs in tissues increase the rate of free radical production to 50-times
the rate of free-radical production by unglycated proteins. Histochemical
analysis of the hippocampus of human cadavers shows that chronological age
can be estimated by hippocampal AGE
levels [[HISTOPATHOLOGY; Sato,Y; 38(3):217-220 (2001)](http://www.ncbi.nlm.nih.gov/pubmed/11260301)].
AGEs attached to LDL-cholesterol accelerates
oxidation and subsequent atherosclerosis. The irreversible cross-linked
proteins of AGEs in vessel collagen also contributes to atherosclerosis, as
well as to kidney failure — conditions worsened in diabetes
[DIABETES 46(Suppl 2):S19-S25 (1997)]. Cataracts are composed of urea-insoluble
proteins in the lens of the eye. AGEs aggravate protein cross-linking
in the plaques & tangles of
[Alzheimer's Disease](../lifeext/Alzheimer.html),
thereby accelerating neuron death [BRAIN RESEARCH REVIEW 23:134-143 (1997)].
AGEs can be formed in the body from glycation & oxidation or can be
ingested directly from browned foods (such as fried poultry skin) or tobacco smoke.
Approximately one third of absorbed dietary AGEs are excreted in urine and rest is
presumably incorporated into body
tissues [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Koschinsky,T;
94(12):6474-6479 (1997)](http://www.pnas.org/cgi/content/full/94/12/6474)]. (For more on the effect of ingested AGEs, see
[INGESTION OF ADVANCED GLYCATION
END-PRODUCTS (AGES)](../health/MacroNut.html#AGEs).)
The higher glycation rate in diabetics is undoubtedly related to
the fact that diabetes greatly resembles accelerated aging. Hemoglobin glycation is
often used as a time-integrated (as opposed to instantaneous) measure of blood
glucose levels in diabetics. AGEs
are universal symptoms of aging — adversely affecting skin, lungs, muscles, blood
vessels and organ-function in general. Increased insulin resistance and other
symptoms of diabetes are commonly seen features of aging. Diabetes-like
atherosclerosis and the resultant generalized reduction in blood flow
has an adverse effect on most organ systems.
Although most proteins are short-lived (mouse liver proteins
have a half-life of 3 days) some proteins, such as crystallins in
the eye lens of mammals, can last a lifetime. Lens crystallines, collagen
and basement membrane are the proteins
most vulnerable to cross-linking and AGE formation because they are
the most long-lived proteins, with a slow rate of turnover.
AGE cross-links
can be broken by N−PhenacylThiazolium Bromide (**PTB**), but
3−phenacyl-4,5-dimethylthiazolum chloride (**ALT−711**,
**[alagebrium](http://en.wikipedia.org/wiki/Alagebrium)**)
has proven to be even more effective than PTB in breaking
cross-links [[CIRCULATION RESEARCH; Candido,R; 92(7):785-792 (2003)](http://circres.ahajournals.org/cgi/content/full/92/7/785)]. Alagebrium
has proven effective in reducing systolic blood
pressure [[AMERICAN JOURNAL OF HYPERTENSION; Bakris,GL; 17(12 Pt 2):23S-30S
(2004)](http://www.ncbi.nlm.nih.gov/pubmed/15607432)] and providing therapeutic benefit for patients with diastolic heart
failure [[JOURNAL OF CARDIAC FAILURE; Little,WC; 11(3):191-195 (2005)](http://www.ncbi.nlm.nih.gov/pubmed/15812746)].
[Carnosine](../nutrceut/carnosine.html) also has anti-glycating
effects [[CURRENT MEDICINAL CHEMISTRY;Guiotto,A; 12(20):2293-2315
(2005)](http://www.ncbi.nlm.nih.gov/pubmed/16181134)].
| Major cross-link in collagen |
In the extracellular matrix of senescent skin, the major protein cross-link
is the arginine-lysine glucose product
**glucosepane** [[REJUVENATION RESEARCH; Svantesson,J; 12(3):137-148 (2009)](http://www.ncbi.nlm.nih.gov/pubmed/19415980)].
In non-diabetic 90-year-olds
glucosepane accounts for about 50 times the cross-linking as all other forms of
cross-linking, and is more than twice as prevalent in diabetics as in
non-diabetics [[JOURNAL OF BIOLOGICAL CHEMISTRY; Sell,DR; 280(13):12310-12315
(2005)](http://www.jbc.org/cgi/content/full/280/13/12310)]. In diabetics, prosclerotic growth factors like **TGF−ß**
(Transforming Growth Factor beta) promote extracellular matrix synthesis.
Collagen accounts for about a third of total body protein in mammals. Collagen
cross-linking in skin, muscle and organs throughout the body leads to the sinewy,
inelastic tissue characteristic of aging. Cross-linking of proteins makes connective
tissue lose elasticity, increases arteriosclerosis, reduces kidney function, slows
wound healing, reduces the vital capacity of the lung and contributes to cataracts.
Cross-linking also contributes to arteriosclerosis by making LDL-cholesterol
unrecognizable to LDL-receptors, thereby increasing LDL in the blood.
Birds have blood glucose levels that are 2−10 times higher, metabolic rates
that are more than double and body temperatures 2ºC−4ºC higher — than
similarly-sized mammals. Higher
temperatures & higher blood glucose would be expected to accelerate
glycation & AGE formation in birds — yet their lifespans are
considerably longer than those of comparably-sized mammals. Hummingbirds have the
highest levels of glycated hemoglobin of any bird, but these levels are lower
than those seen in non-diabetic humans, partially because of higher red blood
cell turnover and partially because of better membrane control of glucose
transport [COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY; Beuchat,CA; 120(Part A):
409-416 (1998)].
**Muscle carnosine correlates with mammalian lifespan**| Muscle carnosine correlates with mammalian lifespan |
Birds have twice the
blood concentration of antioxidant uric acid as humans and a much lower rate of
free radical production. A study of hens showed less than one hundredth the
quantity of [Advanced Glycation End-products (AGES)](../health/MacroNut.html#AGEs) as would be found in
humans [JOURNALS OF GERONTOLOGY; Iqbal,M; 54A(4):B171-B176 (1999)]. The
dipeptide [carnosine](../nutrceut/carnosine.html) (ß−alanyl-L-histidine) both inhibits glycation
and has antioxidant metal chelating activity. Skeletal muscle concentrations
of carnosine correlate with lifespan in mammals [BRAIN RESEARCH REVIEWS
23:134-143 (1997)]. Vitamin C also has anti-glycation properties as well
as antioxidant action [DIABETES; Davie,SJ; 41(2):167-173 (1992)].
Glucose is not the most active sugar for glycation. Galactose is
5 times more reactive than glucose, fructose is 8 times more reactive,
deoxyglucose is 25 times more reactive, ribose is 100 times more reactive
and deoxyribose is 200 times more reactive. [**Sucrose** is composed of the
two monosaccharides glucose & fructose, whereas **lactose** (milk-sugar)
is composed of the two monosaccharides glucose & galactose.] Mice injected
with galactose are models of accelerated
aging [[MECHANISMS OF AGING AND DEVELOPMENT; Song,X; 108(3):239-251
(1999)](http://www.ncbi.nlm.nih.gov/pubmed/10405984)]. Some aldehydes
produced by lipid peroxidation are more reactive than any of the sugars. Glucose
assumes the cyclic conformation more readily than any other monosaccharide, making
it the most resistant to both glycation and oxidation of any sugar. It is
no evolutionary accident that the least reactive of sugars is the sugar organisms
most use for energy.
Lipids as well as proteins are subject to glycation. Lipid glycation of
LDL cholesterol increases the LDL oxidation associated with
atherosclerosis [[ATHEROSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY; Ravandi,A;
20(2):467-477 (2007)](http://atvb.ahajournals.org/cgi/content/full/20/2/467)]. [Vitamin B6](../nutrceut/MiscSupp.html#B6) prevents lipid glycation more effectively than other
common anti-glycation agents [[JOURNAL OF LIPID RESEARCH; Higuchi,O; 47(5):964-974 (2006)](http://www.jlr.org/cgi/content/full/47/5/964)].
(For more information on glycation, see the [International Maillard Reaction Society](http://imars.case.edu/).)
[(return to contents)](#contents)
### X. PROTEIN DAMAGE AND MAINTENANCE IN AGING
Not all of the damaging effects of sugar are due to glycation.
Glucose & fructose are reduced to **sorbitol** by the enzyme aldol
reductase. Sorbitol is a tissue toxin, contributing to retinopathy,
neuropathy, cataracts and kidney disease in diabetes. And not all protein
cross-linking is due to glycation. Aldehydes produced by lipid peroxidation,
such as **M**alon**D**i**A**ldehyde (**MDA**, propanedial),
can cross-link proteins by forming covalent bonds with lysine amino acids.
| | | |
| --- | --- | --- |
| | Cross-linking of protein with lipid peroxidation product MDA |
| --- |
| [ Cross-linking of protein with lipid peroxidation product MDA ] |
|
Mitochondria produce nitric acid at a rate comparable to the rate of superoxide
production [[JOURNAL OF BIOLOGICAL CHEMISTRY; 273(18):11038-11043 (1998)](http://www.jbc.org/cgi/content/full/273/18/11038)].
Peroxynitrite formed by reaction of nitric oxide with superoxide can irreversibly
form covalent bonds with tyrosine amino acids in proteins, thereby blocking phosphorylation.
Phosphorylation & dephosphorylation of enzymes by kinases & phosphatases at tyrosine,
serine & threonine protein residues play a central role in enzyme activation/deactivation
& [cell signalling](http://www.benbest.com/health/cancer.html#signalling) — both of which would be disrupted by
nitrotyrosine formation.
Another form of protein damage is **racemization**, although this kind of
protein damage is less serious than glycation. Cells can only make proteins
from L−isomer ("left-handed") amino acids. Only L−isomer proteins
are functional. Some D−isomer ("right-handed") proteins are not
only non-functional, but harmful. Thermal energy causes a small percentage
of proteins to spontaneously change from the L−form to the D−form
— and this form of molecular deterioration is known as **racemization**.
(Racemization allows for determination of an animal's age from the ratio of
D−form to L−form in the dentine of a tooth).
Asparagine and glutamine amino acids on proteins spontaneously deaminate, especially
when a glycine is in the adjacent carboxyl position. The rate of deamination of asparagine
is 400 times greater than for glutamine. When the enzyme which can repair this protein
damage is missing from experimental (knockout) mice, the mice suffer brain damage and
die young [[JOURNAL OF BIOLOGICAL CHEMISTRY; 276(23):20695-20702 (2001)](http://www.jbc.org/cgi/content/full/276/23/20695)].
**Carbonyl** (**>C=O**, ie, aldehyde or ketone) content of protein is used as
a rough measure of protein oxidation. Carbonyl formation is irreversible, so oxidized
proteins must be removed by degradation. Carbonyl content of protein in an
animal cell increases exponentially with age. At least 30−50% of protein
is oxidized in old animals, which correlates well with an estimated
30−50% decrease in enzyme activity in old animals. A study on houseflies showed an
association between protein carbonyls and life expectancy, possibly indicative of
an effect on rate of
aging [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Sohal,RS;
90(15):7255-7259 (1993)](http://www.pnas.org/cgi/content/abstract/90/15/7255)].
A study of several species of mammals & a bird (pigeon) indicated a linear
relationship between oxidative damage to protein and maximum life span [EXPERIMENTAL
GERONTOLOGY 31(3):365-372 (1996)]. Cysteine & methionine are by far more vulnerable
to oxidation by reactive oxygen species than any other protein amino acids because of
their sulfhydryl groups. Oxidation of cysteine sulfhydryls can result in disulfides that
cause protein aggregation and lipofuscin.
[Naked mole rats](http://en.wikipedia.org/wiki/Naked_mole_rat)
(which live at least 9 times longer than mice) have much more oxidative damage to
proteins than mice, but maintain that level of damage unchanged for two decades. Although
mice have a 12% oxidative decline in cysteine with age, naked mole rats
show no age-related change in cysteine for two
decades [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Perez,VI; 106(9):3059-3064 (2009)](http://www.pnas.org/content/106/9/3059.long)].
[Methionine is oxidized](http://en.wikipedia.org/wiki/Methionine_oxidation) to methionine sulfoxide, but
methionine sulfoxide reductases enzymatically regenerate
methionine [[BIOPHYSICA ET BIOCHEMICA ACTA; Lee,BC; 1790 (11):
1471-1477 (2009)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062201/)]. Additionally, isomerases can reverse the aberrant disulfide
bridges — the only known enzymatic repairs of protein oxidation [FREE RADICAL BIOLOGY
& MEDICINE; Shringarpure,R; 32(11):1084-1089 (2002)]. Transgenic fruit flies that
overexpress methionine sulfide reductase primarily in the nervous system have shown
a median lifespan extension of about
70% [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); 99(5):
2748-2753 (2002)](http://www.pnas.org/cgi/content/full/99/5/2748)]. In one study, methionine sulfoxide reductase
knockout-mice showed reduced lifespan and increased carbonyl content on
protein [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); 98(23):
12920-12925 (2001)](http://www.pnas.org/cgi/content/full/98/23/12920)], but another study showed no reduction in
lifespan [[THE FASEB JOURNAL; Salmon,AB; 23(20):4601-3608 (2009)](http://www.fasebj.org/cgi/content/full/23/10/3601)].
Reducing dietary methionine to a fifth the normal intake has increased
the lifespan of rats by 30% [JOURNAL OF NUTRITION; Orentreich,N; 123(2):269-274 (1993)].
Body weight is just over half normal for the rats and there are increased blood as well
as decreased tissue levels of
glutathione [[THE FASEB JOURNAL; Richie,JP; 8(15):1302-1307 (1994)](http://www.fasebj.org/cgi/content/full/8/15/1302)].
Oxidized protein is more vulnerable to cross-linking by lipid
peroxidation aldehydes such as MDA & 4−HNE [FEBS LETTERS 405:21-25 (1997)].
Hydroxyl radicals cause protein crosslinking by the formation of dityrosine bridges. Oxidized
& cross-linked proteins are resistant to degradation and therefore contribute to the
accumulation of damaged proteins in many degenerative diseases.
Cellular proteins are continually being degraded (hydrolyzed) within cells by
proteolytic enzymes, both for regulation of cellular processes and for "quality control"
of proteins (eliminating malformed or malfunctional ones). Transcription factors and cell-cycle
proteins must be quickly eliminated after having served their purpose. The four major classes
of cellular proteolytic enzymes are (1) caspases (2) calpains (3) cathepsins
and (4) proteasomes.
**Caspases** are mainly active in apoptosis and are therefore in the category of regulatory
proteases. **Calpains** are Ca2+−dependent, ATP-independent proteases that mainly
degrade membrane & cytoskeletal proteins (as well as certain transcription factors). **Cathepsins**
are the major class of proteolytic enzymes found in lysosomes, although there are others. (As well, lysosomes
contain enzymes for degrading lipids, carbohydrates and nucleic acids.)
[Proteasomes](http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/P/Proteasome.html) are enzymatic, proteolytic "machines".
**Proteasome structure and activity**| Proteasome structure and activity |
Normally, most damaged or misfolded protein — as well as obsolete regulatory protein — is
eliminated by the barrel-shaped proteasomes, which are found both in the nucleus and in the
cytoplasm. The core "barrel", called the **20S proteasome**, is capped on one or
both ends by **19S regulatory units**, and the whole structure is called the **26S proteasome**.
Proteins are hydrolyzed inside the 20S proteasome core. The 19S regulatory units assist in
recognition and delivery to the 20S core of proteins that have been marked for degradation by
chains of **ubiquitin** (a 76-amino acid globular protein). **Ubiquitin-activating enzymes** use ATP
to add ubiquitin to proteins requiring degradation. When the chains reach a threshold length of four
ubiquitin subunits, the marked protein is hydrolyzed by the proteasome into reusable peptides and ubiquitin
molecules. Oxidized proteins tend to be partially unfolded (denatured) and more hydrophobic, which may make
them directly recognizable to the 20S cores, such that energy-consuming ubiquitination is not
required for degradation.
Proteasome activity declines with age. Polyubiquinated chains of defective proteins bind to
the 19S regulatory units blocking the passageway and preventing recognition of other
ubiquinated proteins. Even when the 19S regulatory units are clear, accumulating large
masses of cross-linked proteins cannot enter the proteasome, which has a 5−6 nanometer size opening.
Degradation of cellular organelles, proteins and other materials by lysosomes is called
**autophagy**, subdivided into macroautophagy, microautophagy, and CMA. In
**macroautophagy** there is a sequestration of complete portions of the
cytosol (often including phagocytosed material or organelles) into a double membrane vesicle
known as the **autophagosome**, which migrates to the lysosome and fuses with the lysosome
membrane. In **microautophagy** the lysosome membrane itself engulfs portions of the cytoplasm.
Mice with defective autophagy suffer
neurodegeneration [[NATURE; Hara,T; 441:885 (2006)](http://www.ncbi.nlm.nih.gov/pubmed/16625204)] and DNA
damage [[GENES & DEVELOPMENT; Mathew,R; 21(11):1367-1381 (2007)](http://genesdev.cshlp.org/content/21/11/1367.long)]. Macroautophagy is
mainly controlled by the kinase
[mammalian
Target of Rapamycin](http://en.wikipedia.org/wiki/Mammalian_target_of_rapamycin) (**mTOR**), a downstream component of the
[PI3K pathway](http://en.wikipedia.org/wiki/Phosphoinositide_3-kinase),
which is inhibited by [rapamycin](http://en.wikipedia.org/wiki/Sirolimus)
or absence of nutrition. Rapamycin extends both median and maximum lifespan when fed to
mice [[NATURE; Harrison,DE; 460:392-395 (2009)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786175/)]
Proteins can also be brought into the lysosome for degradation by
**Chaperone-Mediated Autophagy** (**CMA**)
in which members of the hsp70 heat shock protein family (the chaperones) attach to a target
protein and then bind to a lysosome receptor protein. CMA operates on proteins having the exposed
**KFERQ** pentapeptide (K=Lysine, F=Phenylalanine, E=Glutamate, R=Arginine, D=Glutamine —
[IUPAC amino acid
abbreviations](http://www.ncbi.nlm.nih.gov/Class/MLACourse/Modules/MolBioReview/iupac_aa_abbreviations.html)) [[MOLECULAR BIOLOGY OF THE CELL; Kiffin,R; 15(11):4829-2840 (2004)](http://www.molbiolcell.org/cgi/content/full/15/11/4829)]. Upon
arrival at the lysosome membrane, the chaparone/protein complex binds to the membrane protein
[LAMP−2a](http://en.wikipedia.org/wiki/LAMP2). The decline in
CMA activity in aging is due to declining LAMP−2a in the lysosome
membrane [[NATURE MEDICINE; Zhang,C; 14(9):959-965 (2008)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722716/)].
Proteins with short half-lives tend to be broken-down by the proteasome, whereas proteins with
half-lives in excess of ten hours tend to be degraded by autophagy. Blockage of proteasomes by
protein aggregates would result in cell dysfunction due to the inability to degrade short-lived
regulatory proteins. Impaired degradation of p53 protein can result in excessive cell senescence or
apoptosis. Impaired proteasome degradation of immune system regulators like I*κ*B can
result in immune deficiency. Protein aggregation can also impair chaperone-mediated autophagy, as in the
case of the aggreations of the presynaptic protein α-synuclein into the Lewy bodies of
Parkinson's Disease [SCIENCE; Cuervo,AM; 305:1292-1295 (2004)].
With aging, lysosomes of postmitotic cells increasingly become bloated
with aggregates of oxidized, glycated, cross-linked proteins which are resistant to enzymatic
degradation — material called [**lipofuscin**](../lifeext/aging.html#toxins).
(When lysosomes become bloated with similar material due to disease processes, it is called **ceroid**.)
The "error catastrophe" theory of aging proposed that accumulating damage to synthesized
proteins resulted in damage to the machinery of synthesis itself, leading to an escalating viscious circle
of malfunctioning cellular components. But the rate of both protein synthesis and protein degradation
declines with age, and the inability to eliminate damaged macromolecules may be more catastropic than
the synthesis of new defective ones.
Ubiquitin levels and protease activity are increased in conditions of stress.
Life extension associated with stress response may stimulate DNA repair or anti-oxidant enzyme production,
but it can also be a form of hibernation & reduced functionality insofar as
shielded proteins are less capable of performing their normal functions.
The production of [**heat-shock proteins**](http://en.wikipedia.org/wiki/Heat_shock_protein) (**HSPs** — cellular
protection from thermal and other stresses) can be increased
by a transient elevation of temperatures that could ordinarily kill a
cell. Increase longevity and robustness resulting from sublethal stress (**hormesis**)
has been demonstrated in fruit flies and nematodes. The magnitude
of induction of heat-shock proteins (particularly the Hsp70 family — which are
approximately 70 kilodaltons in size) is significantly
reduced with aging [EXPERIENTIA 50:1092-1098 (1994)]. The reported
incidence of heat stroke among those 65 years of age or older is ten
times that of younger persons.
Although originally discovered in ***Drosophila*** (fruit flies) in response to
heat, HSPs are now known to also function against other cell stresses such as irradiation,
metal poisons and oxidation (even exercise). HSPs enhance cytokine signalling and antigen
presentation to lymphocytes [ANNALS OF THE NEW YORK ACADEMY OF SCIENCES; Moseley,PL;
856:206-213 (1998)]. Many cancer cells over-express HSPs, enhancing their survival. HSPs
are of remarkably similar structure in nearly all cells, including those from bacteria,
plants and mammals. Birds, however, have a unique heat shock transcription factor that
is induced in cell
proliferation [[THE FASEB JOURNAL; Pirkkala,L; 15(7):1118-1131 (2001)](http://www.fasebj.org/cgi/content/full/15/7/1118)] — suggestive
of the possibility that HSP could be another factor underlying the exceptional longevity
of birds.
Many HSPs are
constitutively expressed (rather than expressed by induction), such as the members of
the ATP-driven Hsp70 family that reside by ribosomes to assist in folding of newly formed
proteins. Some HSPs are true "molecular chaperones" that assist other proteins
in transit across intracellular membranes. Some HSPs may protect telomere proteins
or telomerase. Some HSPs evidently act by binding to incompletely folded metabolic
proteins, protecting them in an inactive state until the traumatic stress
has passed. Elderly transgenic mice that overexpress Hsp70 show a recovery
of muscles from exercise comparable to that seen in young
mice [[THE FASEB JOURNAL; Pirkkala,L; 18(2):355-367 (2004)](http://www.fasebj.org/cgi/content/full/18/2/355)]
Increased expression of the small HSP proteins in the motoneurons of
***Drosophila*** has increased lifespan by 15% when expressed in the
cytoplasm (Hsp23) and 30% when expressed in mitochondria (Hsp22). Despite
the fact that expression was limited to motoneurons, the flies showed an increase in
resistance to oxidative injuries by paraquat of up to
35% [[THE FASEB JOURNAL; Morrow,G; 18(3):598-599 (2004)](http://www.fasebj.org/cgi/content/short/03-0860fjev1)]. The longevity
effect of small HSPs may be due to their ability to prevent toxic aggregations
of proteins.
Heat-shock protein response is reduced in aging cells and is elevated in the cells of
CRAN ([Caloric Restriction with
Adequate Nutrition](../calories/calories.html)) organisms. [Quercetin](../nutrceut/phytochemicals.html#quercetin) promotes
apoptosis in cancer cells (among other cells) by inhibiting the synthesis of heat
shock protein HSP70 [CANCER RESEARCH; Wei,Y; 54:4952-4957 (1994)]. If stress
resistance is primarily due to HSPs, it is noteworthy that stress resistance of
fibroblasts from 8 mammalian species correlates linearly with species lifespan
for a variety of stresses [FREE RADICAL BIOLOGY & MEDICINE; Kapahi,P;
26(516):495-500 (1999)].
[(return to contents)](#contents)
### XI. DNA DAMAGE AND DNA REPAIR
Cell structure and metabolism operates under the direction of genes,
which are located in the **DNA** (**D**eoxyribo**N**ucleic **A**cid)
of the chromosomes of the animal cell nucleus. DNA coding is determined by
4 nucleic acid **bases**: **Adenine**, **Thymine**, **Cytosine**
and **Guanine**. Adenine and Guanine are known as **purines**, whereas
Thymine and Cytosine are **pyrimidines**. **RNA** (**R**ibo**N**ucleic
**A**cid) also contains 4 nucleic acid bases, but differs from DNA by
using the base **Uracil** in the place of Thymine (Uracil is also a
pyrimidine).
The nucleic acid bases combine with either a ribose or
deoxyribose sugar molecule to form **nucleosides**: **Adenosine**,
**Cytidine**, **Guanosine** and **Uridine** in RNA — or
**Deoxyadenosine**, **Deoxycytidine**, **Deoxyguanosine**
and **Deoxythymidine** in DNA. Addition of phosphate groups to nucleosides
results in **nucleotide phosphates**, also called **nucleotides**.
The nucleotides in RNA are **Adenylate**, **Cytidylate**, **Guanylate**
and **Uridylate**. Adenosine TriPhosphate (**ATP**) and deoxyAdenosine
TriPhosphate (**dATP**) are nucleotides.
| PYRIMIDINES | PURINES |
| --- | --- |
| [ PYRIMIDINES ] | [ PURINES ] |
Both purines and pyrimidines are heterocyclic (built from rings that include
both carbon and nitrogen), but pyrimidines consist of a single
ring, whereas purines have two fused rings. Chains of these nucleic
acid molecules are paired with complementary chains to form the
twisting double helix of DNA.
DNA serves as the template (model for copying) for production of both DNA
& RNA. DNA replication (and some DNA repair) is catalyzed by the enzymes
known as **DNA polymerases**. The production of messenger RNA (mRNA) using
DNA as a template is known as **transcription**, and is catalyzed by
**RNA polymerase II** enzyme. Once produced, mRNA leaves the
nucleus for **translation** of the mRNA code into protein on the ribosomes.
| PURINE/PYRIMIDINE BASE-PAIRINGS | BASE-PAIRINGS IN DNA STRANDS | |
| --- | --- | --- |
| [PURINE/PYRIMIDINE BASE-PAIRINGS] | [BASE-PAIRINGS IN DNA STRANDS] |
In normal DNA, the bases Adenine and Thymine are always paired
(connected by 2 hydrogen bonds) and the bases Cytosine
and Guanine are always paired (connected by 3 hydrogen bonds). A specific
sequence of 3 bases in DNA will cause the selection of a single amino acid
for protein synthesis. For example, GCA (Guanine, Cytosine, Adenine) will
select the amino acid Alanine in the synthesis of structural proteins and
enzymes. A **gene** is a hereditary unit composed of a sequence of
DNA bases that will code for a sequence of amino acids that form a
peptide or protein.
The DNA bases are connected to sugar molecules (deoxyribose) and
the sugar molecules are linked together by phosphate molecules. More
precisely, an ester bond (oxygen bond) connects the 5' carbon
of one deoxyribose and another ester bond connects the 3' carbon
to another deoxyribose, and both ester bonds are connected to a phosphate,
forming a 5',3'−phosphodiester bond. The phosphate-linked sugars connected
to the bases form a single strand of DNA, which pairs with an ***antiparallel***
strand of 3',5'−phosphodiester bonds to form the DNA double-helix.
| Single Strand of DNA |
| --- |
| [Single DNA strand] |
Animal genetic material in
the cell nucleus exists as a complex known as **chromatin** — which
consists of DNA, five histone proteins and some non-histone proteins.
**Histone** protein is not coagulated by heat and is composed of a
high proportion of the basic amino acids lysine & arginine, which are
positively-charged at physiological pH. Because DNA is negatively-charged
(due to phosphate groups), the positively-charged histones readily bind
to DNA.
Four of the histones (H2A, H2B, H3 and H4) compact DNA about six-fold
into bead-like **nucleosomes**. A fifth histone (H1) binds to the DNA
between nucleosomes, causing a second-order compacting of the "string"
— compacting the chromatin another six-fold. Non-histone proteins aid
an even higher level of looping & coiling. With age, compacting of
chromatin increases, probably due to increasing covalent linking
between DNA and the chromosomal proteins. Because compacting helps determine
which genes are expressed and which genes are not, the increased
compacting of aging probably means a decline in gene expression. A 50%
reduction in chromatin-associated RNA polymerase II activity has been
demonstrated in the brains of old rats [MUTATION RESEARCH 275:317-329
(1992)].
| BEAD-LIKE NUCLEOSOMES | H1-COMPACTED NUCLEOSOMES | |
| --- | --- | --- |
| | |
Of the approximately 30,000 genes in the human
genome, it is estimated that only 2% of these are different from those of
a chimpanzee, which has half the estimated maximum lifespan of a human. The
longevity difference could be due to as few as a hundred genes or less. Also
of note is the fact that identical twins tend to die within 3 years of each
other, whereas fraternal twins tend to die within 6 years. Aging theories
associated with DNA include programmed aging (or programmed aging-resistance)
and theories that link aging with DNA damage/mutation or DNA repair
capability.
"Wear&tear" of DNA can take two forms: mutation and DNA
damage. An analogy
illustrates the difference: the word ST**O**P can be **mutated** to
the word ST**E**P by the substitution of another letter, whereas if the
letter "O" is lost or altered, **damage** occurs, resulting in
the non-word ST**#**P. Substitution of a Thymine for an Adenine
would be a **mutation**, whereas loss of an Adenine
or methylation of a Guanine would be **damage**. The phenomena are not
independent, however, because methylated Guanine is known to be mutagenic.
Of chemicals known to be mutagenic in bacteria 85% are
carcinogenic (cancer-causing) in animals &mdas the basis of the
[Ames Test](http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/AmesTest.html) for carcinogenicity.
DNA damage tends to interfere with gene expression by preventing
transcription of RNA from DNA, whereas mutation usually results in
transcription that usually produces proteins with diminished or
altered functionality. Mutations that are not lethal to a cell are more
likely to be perpetuated in dividing cells. DNA damage rather than DNA
mutation is posited as a cause of aging.
There are more than 200,000 DNA damage events per mammalian cell per
day due to oxidation, hydrolysis, alkylation, radiation or toxic chemicals.
Removal of purine or
pyrimidine bases from DNA (**depurination** and **depyrimidation** )
is often caused by hydrolysis or thermal disruption. The location on DNA where a
depurination or depyrimidation has occurred is called an **AP site**
(**AP**urinic or **AP**yrimidinic site). If AP sites are unrepaired
they decay to single-strand breaks. **Pyrimidine dimers** (usually cross-linking
of two adjacent thymine bases) frequently are produced by ultraviolet light.
Types and frequency of DNA damage can be roughly illustrated
by the following table and representative pictures:
![[DEPICTIONS OF DNA DAMAGE]](break.gif)
### **Types and Frequency of DNA Damage**
| **TYPE OF DAMAGE** | **events/cell/day** | **% of total daily damage** |
| **Single-strand break** | **120,000** | **50.9** |
| **N7-MethylGuanine** | **84,000** | **35.6** |
| **Depurination** | **24,000** | **10.2** |
| **O6-MethylGuanine** | **3,120** | **1.3** |
| **Oxidized DNA** | **2,880** | **1.2** |
| **Depyrimidation** | **1,320** | **0.5** |
| **Cytosine deamination** | **360** | **0.2** |
| **Double-strand breaks** | **9** | **0.01** |
| **Interstrand cross-links** | **8** | **0.01** |
| Illustrated Summary of Types of DNA Damage |
| --- |
| [DNA Damage Illustration] |
**OXIDATIVE DAMAGE TO A NUCLEOSIDE: formation of 8−OHdG/8−oxoG**| | 8−OHdG from Guanosine with Hydroxyl | 8−oxoG |
| --- | --- |
| [ 8−HydroxdeoxyGuanosine ] | [8−oxo−7,6−dihydroGuanine ] |
|
More than 20 types of oxidative damage to nucleosides have been
documented [[THE FASEB JOURNAL; Cooke,MS; 17(10):1195-1214 (2003)](http://www.fasebj.org/cgi/content/full/17/10/1195)].
The most frequent oxidative damage to DNA is believed to be the 8−hydroxylation/oxidation
of the guanine base to 8−hydroxydeoxyguanosine (**8−OHdG**), a molecule which is
equivalent to 8−oxo−7,8−dihydroguanine (**8−oxoG**) because
the hydroxyl hydrogen can easily move to the 7−position leaving a double-bonded oxygen
at the 8−position (a resonance form of the two structures). Singlet
oxygen reacts with DNA to produce
8−OHdG/8−oxoG [[JOURNAL OF BIOLOGICAL CHEMISTRY; Ravanat,J; 275(51):40601-50604 (2000)](http://www.jbc.org/cgi/content/full/275/51/40601)].
8−OHdG/8−oxoG is the most commonly studied biomarker of DNA oxidation [MUTATION
RESEARCH 424:51-58 (1999)] and is believed to constitute 5% of all oxidative DNA
damage [MUTATION RESEARCH; Dizdaroglu;M; 275(2-6):331-342 (1992)].
8−OHdG is mutagenic because it inhibits methylation and because it can be paired with
adenosine rather than cytosine during DNA replication leading to GC-to-AT conversion
(the most frequent kind of spontaneous mutation). Levels of 8−OHdG are inversely
related to lifespan in mammals [FREE RADICAL BIOLOGY & MEDICINE; Foksinski,M;
37(9):1449-1454 (2004)], and increase with age — but less so in animals
subjected to [Caloric Restriction with Adequate Nutrition](../calories/calories.html) (CRAN) [FREE RADICAL BIOLOGY &
MEDICINE 32(9):882-889 (2002)]. Mitochondrial DNA rather than nuclear DNA is the primary
site of damage [[THE FASEB JOURNAL; Barja,G; 14(2):312-318 (2000)](http://www.fasebj.org/cgi/content/full/14/2/312)].
In Western countries, females live about 10% longer than
males, and males have 4 times as much oxidative DNA damage
as females, presumably because females have more MnSOD and glutathione
peroxidase [[FREE RADICAL BIOLOGY & MEDICINE;
Borras,C; 34(5):546-552 (2003)](http://www.ncbi.nlm.nih.gov/pubmed/12614843)]. Levels of
8−OHdG are 18 times higher than normal in intact DNA from the cerebrospinal fluid
of [Alzheimer's
Disease](http://www.benbest.com/lifeext/Alzheimer.html) patients [ARCHIVES OF NEUROLOGY 58:392-396 (2001)]. Nuclear DNA in the
brain tissue of old mice accumulates 8−OHdG/8−oxoG at nearly four times the rate of young
mice [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Hamilton,ML;
98(18):10469-10474 (2001)](http://www.pnas.org/cgi/content/full/98/18/10469)]. Repair of 8−OHdG/8−oxoG has been shown to decline
significantly with age in
humans [[JOURNAL OF RADIATION RESEARCH; Chen,S; 44(1):31-35 (2003)](http://www.jstage.jst.go.jp/article/jrr/44/1/44_31/_article/-char/en)]. Cigarette
smoking, age, and unhealthy diet correlate directly with not only urinary 8−OHdG/8−oxoG,
but urinary
N7-MethylGuanine [[CANCER SCIENCE; Tamae,K; 100(4):715-721 (2009)](http://www3.interscience.wiley.com/cgi-bin/fulltext/121676017/HTMLSTART)].
The most active DNA repair enzymes, **excision repair** enzymes, all operate on the
basis of damage or mutilation occurring to only one of the two strands of the DNA
double-helix such that the undamaged strand can be used as a template to repair the
damaged strand. The damaged area of the injured strand is cut-away (**excised**) by a
nuclease (or glycosylase) enzyme, and a new strand (or a single nucleotide) is constructed.
Even the simplest repair usually involves a team of enzymes.
**Glycosylase** (glycosidase) enzymes remove individually damaged nucleic acid bases (purines or
pyrimidines) from the deoxyribose sugars to which they are attached. Glycosylases remove
bases that have been oxidized or alkylated and also remove uracil from nDNA. The **MYH**
glycosylase removes adenine that has been incorrectly incorporated opposite 8−OHdG/8−oxoG.
**Endonuclease**
enzymes cleave the phosphodiester bonds to remove the sugar residues (which may or may
not still be connected to a base). There are at least fifteen **DNA polymerase**
enzymes which function in DNA repair to replace excised strands of DNA. **DNA ligase**
enzymes seal the strand by reforming the phosphodiester bonds. If a long section of
strand needs to be replaced, **helicase** enzymes may be required to unwind the DNA
before the injured section is excised — and rewind afterwards. Very long sections may
even require **topoisomerase** enzymes to unwind and rewind supercoils. Additional
enzymes are often required to recognize damage and recruit other enzymes into repair.
There are three general categories of excision−repair enzymes:
(1) **Base Excision Repair** (**BER**, which repair/replace a single damaged
nucleic acid base) (2) **Nucleotide Excision Repair** (**NER**, for repairing
DNA strand damage ranging from 2−30 bases in length) and (3) **MisMatch Repair**
(**MMR**, for repairing mispaired nucleic acid bases).
**Base Excision Repair**| Base Excision Repair |
**Deamination of Cytosine**| Deamination of Cytosine |
**Base Excision Repair** (**BER**) primarily repairs damage due to hydrolysis,
alkylation (usually methylation) or oxidation of single nucleic acid bases. Alteration of a
single base may not impede transcription and can often lead
to miscoding and thus to mutation. BER begins with recognition and removal of a damaged
nucleic acid base by one of many possible glycosylase enzymes, each of which specializes
in recognition of a particular type of base
damage [[BIOCHEMICAL JOURNAL; Krokan,HE; 325(Pt 1):1-16 (1997)](http://www.biochemj.org/bj/325/0001/bj3250001.htm)].
BER has two subpathways, known as **short-patch BER**
and **long-patch BER**. Roughly 80−90% of BER is by the short-patch pathway,
which requires only 3 enzymes: a glycolsylase, an endonuclease and a polymerase.
Bifunctional glycosylases not only cleave the bond between the damaged base and the
sugar, but cleave the backbone with AP lyase activity. But
for obstinate base modification that cannot be fixed by the short-patch pathway, the
long-patch pathway strips-away 2−10 nucleotides, including the damaged base. A
larger number of proteins participate in the long-patch pathway, such as PCNA, RFC,
FEN1 and probably WRN. PCNA, RFC and a polymerase create a "flap" of
nucleotides that are removed by FEN1 (Flap ENdonuclease−1);
Deamination of cytosine by hydrolysis is an example of DNA damage
repaired by short-patch BER. With the removal
of the (−NH2) group, cytosine becomes uracil, which is recognized by DNA
repair enzymes as being an abnormal base in DNA. (The fact that cytosine deaminates
so easily to uracil probably explains why thymine rather than uracil is normally
present in DNA — it is easier to detect a base not normally present). The repair
enzyme **uracil-DNA glycosylase** removes the uracil and then an **AP endonuclease**
cleaves the phosphodiester bonds, just as it would in the repair of any depurination or
depyrimidation. **DNA polymerase ß** is a specialized DNA polymerase that
is used for attaching the new base in BER, not for DNA replication. BER repair capabilities
dependent upon DNA polymerase ß have been shown to decline with age in mice, which
may underly increased vulnerability to cancer or even aging itself [MUTATION RESEARCH
500:135-145 (2002)]. Normal BER forms transient single-strand breaks, so it is
understandable that BER enzymes play an important role in single-strand break repair.
There are no known diseases associated with inherited defects of short-patch BER enzymes.
Individual glycosylase defects are not harmful because there are so many glycosylases which
can perform the same functions, whereas defects in the other short-patch BER enzymes are
fatal to embryos.
One might imagine that increased expression of BER enzymes would improve DNA integrity,
but the opposite is true. Increased glycosylase expression increases DNA strand
breaks [[MOLECULAR CANCER THERAPIES; Rinne,M; 3(8):955-967 (2004)](http://mct.aacrjournals.org/cgi/content/full/3/8/955)] as
does increased DNA polymerase ß
expression [[NUCLEIC ACIDS RESEARCH; Canitrot,Y; 32(17):5104-5112 (2004)](http://nar.oxfordjournals.org/cgi/content/full/32/17/5104)].
Increased AP nuclease expression can increase genetic
instability [[NUCLEIC ACIDS RESEARCH; Sossou,M; 33(1):298-306 (2005)](http://nar.oxfordjournals.org/cgi/content/full/33/1/298)]. Insofar as
the stages of DNA repair involve creation of AP sites and clipping of DNA strands, these
results should not be surprising. Enhanced DNA repair would require co-ordinated
increase in many enzymes.
**Ultraviolet photoproducts**| Ultraviolet photoproducts |
**Nucleotide Excision Repair** (**NER**) repairs damage affecting more than one
nucleic acid base, defects which distort the DNA helix and can be exemplified by the
repair of cross-links between purines & the deoxyribose-phosphate backbone due to the
hydroxyl radical and by **pyrimidine dimers** (**CPD**s, Cyclobutane Pyrimidine Dimers,
two covalently-bonded adjacent pyrimidines, usually **thymine dimers**) caused by
ultraviolet light. Thymine-cytosine and cytosine-cytosine are the most mutagenic
CPDs [JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY; Marrot,L;
58(5 Suppl 2):S139-S148 (2008)]. Less frequently than CPDs, ultraviolet
light also induces 6−4 pyrimidine-pyrimidone photoproducts
(**6−4 PP**s). **CPD**s and **6−4 PP**s lead to
apoptosis [[BMC CANCER; Lo,H; 5:135 (2005)](http://www.biomedcentral.com/1471-2407/5/135)] or double-strand
breaks [[THE EMBO JOURNAL; Garinus,GA; 24(22):3952-3962 (2005)](http://www.nature.com/emboj/journal/v24/n22/abs/7600849a.html)]
if not repaired by NER. [Carcinogen](../health/cancer.html#chemicals) lesions like those caused by aflatoxin (which forms bulky
DNA adducts) are also corrected by NER. **DNA polymerase delta** and **DNA polymerase epsilon**
are the specialized DNA polymerases used in NER. Many steps and more than 20 proteins are
involved in unwinding the DNA, in recognizing the type
of damage to be repaired, etc. NER provides backup to BER when glycosylases are defective in
the nucleus, but NER systems are absent from mammalian mitochondria (which only have BER).
A consequence of the fact that NER is so much more complex than BER is the fact that NER is more
error-prone than BER. A study of seven mammalian species showed a correlation between
both rate and extent of NER after UV exposure and lifespan of the
species [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Hart, RW;
71(6):2169-2173 (1974)](http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=4526202)].
**Nucleotide Excision Repair**| Nucleotide Excision Repair |
There are two subtypes of NER, distinguished by how damage is recognized:
(1) **Global-Genome Repair** (**GGR**, recognizes damage throughout
the genome) and (2) **Transcription-Coupled Repair** (**TCR**, recognizes damage
by stalled transcription). The slower **GGR NER** (like all the DNA repair mechanisms
other than TCR) gradually covers the whole exposed genome. GGR recognizes strand
defects with **XP protein** — so-named because defects in these
[helicase](http://en.wikipedia.org/wiki/Helicase) (DNA helix
unwinding) proteins (identified alphabetically from **XPA** to **XPG**) lead to the
disease known as **Xeroderma Pigmentosum**. The XP helicase unwinds DNA in the area
of the DNA damage so that other NER enzymes can make the repair. XPB & XPD are subunits
of [**Transcription Factor IIH**](http://en.wikipedia.org/wiki/Transcription_Factor_II_H) (**TFIIH**), which functions in normal
transcription as well as in NER. **XPF−ERCC1** is an endonuclease wherein XPF is the
catalytic component and ERCC1 is required for DNA binding. **TCR NER** is a preferential
NER pathway focused on genes that are being transcribed. TCR ensures that DNA that is actively
being transcribed is given the highest priority for repair. Typically a TCR enzyme detects a
stalled RNA polymerase which is unable to proceed because of the DNA damage. The detection proteins
are called **CS proteins** because when they are defective the result is a disease known as
**Cockayne Syndrome**. CS proteins aid in displacement of the stalled RNA polymerase to
allow NER enzymes to access the damaged DNA. Then the XP helicase does the unwinding and
TCR NER then proceeds much as it would for global NER. The tumor-suppressor protein **BRCA1**
(which is often defective in
[breast cancer](../health/cancer.html#breast)) is essential
for TCR associated with oxidative DNA damage (but not with TCR associated with
ultraviolet light damage) [SCIENCE; Gowen,LC; 281:1009-1012 (1998)]. Defects in GGR lead to
cancer, whereas defects in TCR more readily lead to apoptosis ("accelerated
aging") [NATURE REVIEWS; Ljungman,M; 4(9):727-737 (2004)]. Nonproliferative
cells do not exhibit GGR, only exhibiting DNA repair on transcribed
genes [[MOLECULAR AND CELLULAR BIOLOGY; Nouspikel,T; 20(5):1562-1570 (2000)](http://mcb.asm.org/cgi/content/full/20/5/1562)
and [MUTAGENESIS; Bielas,JH; 21(1):49-53 (2006)](http://mutage.oxfordjournals.org/cgi/content/full/21/1/49)].
**MisMatch Repair** (**MMR**) corrects errors made during DNA copying, such as
the mispairing of an adenosine base with a guanosine. MMR can correct A−C &
T−C mismatches more efficiently than G−A & T−C mismatches, and
does a very poor job of correcting C−C
mismatches [[BIOCHEMICAL JOURNAL; Marra,J; 338(Pt 1):1-13 (1999)](http://www.biochemj.org/bj/338/0001/bj3380001.htm)].
But how do the recognition enzymes
know which is the correct base, the adenosine or the guanosine? For bacteria, the answer
is known: when DNA is freshly synthesized the parental strand has methyl groups
attached to certain adenosine residues, whereas the newly synthesized strand will be
unmethylated for some time after replication. Prior to methylation of the new strand
the detection enzymes can look for errors. DNA methylation is apparently not used for
error-detection in multi-cellular organisms, however, and the means of mismatch
detection is still unknown. Mismatch repair differs
from BER only in the first glycosylase, which recognizes and removes ***mispaired***
bases — in contrast to BER which recognizes and removes ***defective*** bases. Removing
the mispaired base leaves an AP site which can then be repaired by the subsequent BER
enzymes. Failures in MMR result in mutations, whereas failures in BER result in
DNA damage (including mutations). Defects in MMR operation result in mutation rates 100−fold
greater than seen in normal cells, most often in
[microsatellite](http://en.wikipedia.org/wiki/Microsatellite) sequences.
MMR corrects not only single base mispairs, but
Insertion/Deletion Loops (**IDL**s) that result from strand misalignments, which
can produce **frameshift mutations** (disrupted triplet codon reading due to
insertion or deletion of base pairs that is not a multiple of 3).
As well, MMR plays a significant role in protecting against
incorporation of 8−OHdG/8−oxoG into
DNA [[MOLECULAR AND CELLULAR BIOLOGY; Russo,MT; 24(1):465-474 (2004)](http://mcb.asm.org/cgi/content/full/24/1/465)].
[Hereditery
NonPolyposis Colon Cancer (HNPCC)](../health/cancer.html#colon) is often caused by defective **Msh2** protein,
which normally functions to recognize mispaired bases and to signal
MMR [[JOURNAL OF BIOLOGICAL CHEMISTRY; Mazurek,AM; 277(10):8260-8266 (2002)](http://www.jbc.org/cgi/content/full/277/10/8260)].
MMR also protects against cancer by inhibition of **ALT** (Alternative Lengthening of
Telomeres) [[CANCER RESEARCH; Bechter,OE; 64(10):344-3451 (2004)](http://cancerres.aacrjournals.org/cgi/content/full/64/10/3444)].
DNA repair enzymes exist for double-stand breaks and for guanine methylation, neither
of which involve excision of single DNA strands. Methylation of cytosine is a normal means
by which cells prevent gene expression. But methylation of guanine is DNA damage,
and deamination of a methylated cytosine results in thymine — a
mutation. A "suicidal" methyl transferase enzyme can repair
O6−methylguanine by transferring the methyl group to its own cysteine.
The DNA repair enzyme O6−**M**ethyl**G**uanine-DNA
**M**ethyl**T**ransferase (**MGMT**) is frequently repressed by hypermethylation
in colon cancer, which thereby allows alkylating agents to cause the **G:C**-to-**A:T**
conversions which are behind the **K−ras** mutation seen in about half of
[colorectal carcinomas](../health/cancer.html#colon). MGMT can
remove not only methyl groups from guanine, but chloroethyl and benzyl groups. Because MGMT
corrects the nucleotide without removal, it is said to do repair by
**Direct Reversal** (**DR**).
**Double-Strand Breaks** (**DSBs**) normally occur during
[V(D)J recombination](http://en.wikipedia.org/wiki/V(D)J_recombination)
and [meiosis](http://en.wikipedia.org/wiki/Meiosis)
where [genetic
recombination](http://en.wikipedia.org/wiki/Genetic_recombination) can be beneficial. Damaging DSBs are usually due to ionizing radiation
or very high doses of alkylating carcinogens such as nitrogen mustards. When the damage
is not so severe **Single-Strand Breaks** (**SSBs**) may result. Even with
ionizing radiation, double-strand breaks are only produced with about a tenth the frequency
of single strand breaks. Although double-strand breaks are rare, they are difficult
to repair and can be very injurious for somatic cells that undergo mitosis.
(The [Deinococcus radiodurans](http://en.wikipedia.org/wiki/Deinococcus_radiodurans) bacterium that lives in
nuclear reactors repairs double-strand damage very efficiently.) DSBs are repaired by
(1) **Non-Homologous End-Joining** (**NHEJ**) or (2) **Homologous Recombination**
(**HR**). NHEJ is the simplest and most common means of DSB repair, but it is the least
accurate. For NHEJ the two broken ends are rejoined without regard to deletions or
rearrangements. By contrast, HR exactly reconstitutes the original sequence of genes because
the sister chromatid (during [mitosis](http://en.wikipedia.org/wiki/Mitosis))
or homologous chromosome
(during [meiosis](http://en.wikipedia.org/wiki/Meiosis)) is used.
But HR is limited by the fact that it can only operate during meiosis or late mitosis. NHEJ is
the only repair mechanism available for non-mitotic cells, whereas for mitotic cells NHEJ
operates in the G0, G1 and early S phase of the
[cell cycle](../health/cancer.html##cellcycle), whereas HR
operates in late S phase and G2.
DSBs are recognized by the **MRN complex** (composed of Mrell, Rad50 and Nbs1
proteins), which unwinds the DNA ends and recruits **ATM** protein to the
site of the break [SCIENCE; Lee,J; 308:551-554 (2005)]. ATM phosphorylates
**H2AX histone** (which recruits DNA repair proteins [SCIENCE; Celeste,A;
296:992-997 (2005)]) and **p53 protein** (which blocks progression
through the [cell
cycle](../health/cancer.html#cellcycle) leading to DNA repair or apoptosis — if DNA damage is too great
for available DNA-repair resources). ATM is responsible for phosphorylation of
Rad51 protein required for
HR [[JOURNAL OF BIOLOGICAL CHEMISTRY; Chen,G; 274(18):12748-12752 (1999)](http://www.jbc.org/cgi/content/full/274/18/12748)].
ATM regulates not only HR, but a more precise form of
NHEJ [[CANCER RESEARCH; Wang,H; 66(3):1391-1400 (2006)](http://cancerres.aacrjournals.org/cgi/content/full/66/3/1391)].
**Non Homologous End-Joining for DSB Repair**| Non Homologous End-Joining for DSB Repair | Non Homologous End-Joining for DSB Repair |
DSB repair is even more error-prone than NER, especially in the case of NHEJ.
The **WRN** protein, which is defective in **Werner's syndrome**, operates in DSB repair
by both NHEJ and HR [[NUCLEIC ACIDS RESEARCH; Brosh,RM; 35(22):7527-7544(2007)](http://nar.oxfordjournals.org/cgi/content/full/35/22/7527)]. WRN protein
minimizes nucleotide loss during
NHEJ [[CANCER RESEARCH; Oshima,J; 62(2):547-551 (2002)](http://cancerres.aacrjournals.org/cgi/content/full/62/2/547)]. Cells lacking WRN
may have such inefficient HR that they are dependent on forms of NHEJ for DSB
repair [[GENES & DEVELOPMENT; Prince,PR; 15(8):933-938 (2001)](http://genesdev.cshlp.org/content/15/8/933)]. The
**Ku** protein heterodimer (Ku70/Ku86)
initiates NHEJ by binding to broken DNA ends and bringing them together. (Ku86 (mice?) is
sometimes called Ku80, but is actually
83 [kiloDaltons](http://en.wikipedia.org/wiki/Atomic_mass_unit).)
**Ku** heterodimers are so plentiful in mammalian nuclei that any DSB is likely to occur
within five molecular diameters of a **Ku** dimer. Both the **Ku** heterodimer
& the DNA-dependent Protein Kinase complex (**DNA−PKc**) bind to
WRN protein and regulate WRN
activity [[JOURNAL OF BIOLOGICAL CHEMISTRY; Karmakar,P; 277(21):18291-18302
(2002)](http://www.jbc.org/cgi/content/full/277/21/18291)]. WRN unwinds the DNA strands and then **Ku** attachment to WRN
strongly stimulates endonuclease activity in preparation for
ligation [[CARCINOGENESIS; Opresko,PL; 24(5):791-802 (2003)](http://carcin.oxfordjournals.org/cgi/content/full/24/5/791)]. Overexpression
of **Ku** in normal yeast reduces gross chromosomal rearrangements, but **Ku** overexpression
increases gross chromosomal rearrangement in strains having a defective WRN
homolog [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Banerjee,S;
103(6):1816-1821 (2006)](http://www.pnas.org/cgi/content/full/103/6/1816)]. Ku86 and DNA−PKc are also important for telomere
maintenance [[THE JOURNAL OF CELL BIOLOGY; Espejel,S; 167(4):627-638 (2004)](http://www.jcb.org/cgi/content/full/167/4/627)].
The nuclease **Artemis** processes damaged DNA ends prior to ligation
(rejoining) [[CELL CYCLE; Jeggo,PA; 4(3):359-362 (2005)](http://www.landesbioscience.com/journals/cc/article/1527/)].
The tumor-suppressor protein **BRCA1** has also been shown to play a critical role in
NHEJ [[HUMAN MOLECULAR GENETICS; Deng,C; 12(1):R113-R123 (2003)](http://hmg.oxfordjournals.org/cgi/content/full/12/suppl_1/R113)]. Although NHEJ is
"molecular guesswork" and very error prone, it is often effective because most of the
genome is composed of "junk DNA". One or more alternate forms of NHEJ exist, and
these alternate NHEJ forms are even more error-prone and mutagenic than primary
NHEJ [[PLoS GENETICS; Bennardo,N;4(6):1-10(2008)](http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000110)]. **Ku** protein has a
much higher affinity for DNA ends than PARP−1 does, but in the absence of **Ku**
PARP−1 will bind to DNA ends to provide a more error-prone "backup" form of
NHEJ [[NUCLEIC ACIDS RESEARCH; Wang,M; 34(21):6170-6182 (2006)](http://nar.oxfordjournals.org/cgi/content/full/34/8/2269)].
**Homologous recombination** (**HR**, also called **REcombinational Repair**,
**RER**), a more
accurate but less frequently-used means of DSB repair, is the dominant method used in
the late S and G2 phases of the cell-cycle, after a sister chromatid has
been created. Although HR is primarily restricted to repair of DSBs in proliferating
cells, even in proliferating cells 75% of DSBs are repaired by NHEJ [DNA REPAIR;
Mao,Z; 7(10):1765-1771 (2008)]. **ATR** (**AT**M and **R**ad3-related) checkpoint
protein facilitates HR [[CANCER RESEARCH; Wang,H; 64(19):7139-7143 (2004)](http://cancerres.aacrjournals.org/cgi/content/full/64/19/7139)] and senses stalled
DNA replication forks [DNA REPAIR; Paulsen,RD; 6(7):953-966 (2007)], but ATR does
not facilitate NHEJ [[CANCER RESEARCH; Wang,H; 64(19):7139-7143 (2004)](http://cancerres.aacrjournals.org/cgi/content/full/64/19/7139)]. (ATR is most active in
proliferative tissues.) In one form of HR (**synthesis-dependent strand annealing**) a single
DNA strand must associate with its complementary strand in a double-stranded DNA
molecule. In a simpler form of HR (**single-strand annealing**, which requires
fewer proteins) a single strand associates with its complementary single strand.
Homologous pairing of the sister chromatids is often mediated by **Rad51**
protein, which is normally necessary for cell proliferation and survival. **Rad52**
protein recognizes the DSB and adheres to the free ends of the break (comparable to
**Ku** in NHEJ) while **Rad51**
searches the undamaged sister chromatid for a homologous repair template. The tumor
suppressor protein **BRCA2** co-localizes with Rad51 during homologous recombinational
repair, and contributes significantly to its
activity [[BREAST CANCER RESEARCH; Orelli,BJ; 3(5):294-298 (2001)](http://breast-cancer-research.com/content/3/5/294)]. HR could be
a basis for telomerase-independent telomere lengthening (ALT) in
mammals [[THE EMBO JOURNAL; Blasco,MA; 24(6):1095-1103 (2005)](http://embojournal.npgjournals.com/cgi/content/abstract/21/10/2383)].
**Homologous Recombination (HR)**| Homologous Recombination (HR) |
For HR during
meiosis there can be a loss of information ("loss of
[heterozygosity](http://en.wikipedia.org/wiki/Zygosity)")
if a **gene conversion** (replacement of two different
[alleles](http://en.wikipedia.org/wiki/Allele) by the
same allele on both chromosomes) occurs.
**Homologous Recombination (HR) products**| Homologous Recombination (HR) products |
**TransLesion Synthesis** (**TLS**) uses specialized DNA polymerases to quickly
patch damaged strands. Although more error-prone than BER, NER or MMR, TLS may reduce the
danger of DSBs [[GENES & DEVELOPMENT; Prakash,S; 16(15):1872-1883 (2002)](http://www.genesdev.org/cgi/content/full/16/15/1872)].
The bacterium *Deinococcus radiodurans* is the most radiation-resistant organism known.
Within one day of exposure to radiation inducing hundreds of DSBs the entire genome is
usually faithfully restored. The bacterium has a wide range of DNA repair enzymes and a
high amount of redundancy in the genes for those enzymes. With 4−10 copies of the entire
genome per cell, the polyploid bacterium has access to numerous templates for homologous
recombination [SCIENCE; White,O; 286:1571-1577 (1999)].
**Single-Strand Breaks** (**SSBs**) must be repaired quickly to prevent
them from becoming DSBs. An NAD-dependent enzyme named **Poly(ADP-Ribose) Polymerase−1**
(**PARP−1**) binds to SSBs and recruits
[XRCC1](http://en.wikipedia.org/wiki/XRCC1) protein, which provides
the scaffold necessary for
[DNA
polymerase β](http://en.wikipedia.org/wiki/DNA_polymerase_beta) to fill the
gap [[CELL RESEARCH; Horton,JK; 18(1):48-63 (2008)](http://www.nature.com/cr/journal/v18/n1/full/cr20087a.html)]. In response to
single-strand DNA damage due to alkylating agents, oxidants or ionizing radiation,
levels of PARP−1 can increase several hundred-fold. Maximum lifespan in mammalian
species correlates with PARP
activity [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Grube,K;
89(24):11759-11763 (1992)](http://www.pnas.org/cgi/content/abstract/89/24/11759)]. PARP−1 modifies histones, transcription
factors and other nuclear regulatory proteins by addition of many ADP-ribose molecules to the
glutamic acid residues — increasing negative charge and thereby causing proteins to
unfold or become more open. PARP−1 addition of long ADP-ribose tails to histones can quickly
decondense chromatin to enable rapid transcription [SCIENCE; Pirrotta,V;
299:528-529 (2003)] and access for DNA repair [SCIENCE; Tulin,A; 299:560-562 (2003)]. The
ADP-riboses come from removing nicotinamide from NAD+ (**N**icotinamide **A**denine
**D**inucleotide). Poly (ADP-ribosyl)ation is a transient protein modification that is
rapidly reversed by poly (ADP-ribose) glycohyrolase. In addition to SSBs, PARP−1 functions
in BER and NHEJ to detect DNA damage and recruit DNA repair
enzymes [[JOURNAL OF BIOLOGICAL CHEMISTRY; Schreiber,V; 23028-23036 (2002)](http://www.jbc.org/cgi/content/full/277/25/23028)
and [JOURNAL OF BIOLOGICAL CHEMISTRY; Audebert,M; 279(53):55117-55126
(2004)](http://www.jbc.org/cgi/content/full/279/53/55117)], but may require the **WRN** protein to do
so [[MOLECULAR AND CELLULAR BIOLOGY; 23(23):8601-8613 (2003)](http://mcb.asm.org/cgi/content/full/23/23/8601)].
PARP−1 and WRN seem to interact in NHEJ as well as
BER [[NUCLEIC ACIDS RESEARCH; Beneke,S; 35(22):7456-7465 (2007)](http://nar.oxfordjournals.org/cgi/content/full/35/22/7456)].
Some protection against DNA damage is provided by gene redundancy. But
the only structural genes known to be present in multiple copies are those
coding for ribosomal RNA (rRNA), transfer RNA (tRNA) and histones. **Apoptosis**
(cell suicide) is the most effective defense against DNA damage & mutation
when DNA repair enzymes are inadequate to fix the damage. But p53 induction following UV
irradiation declines with age, as do levels of DNA repair
proteins [[THE FASEB JOURNAL; Goukassian,D; 14(10):1325-1334 (2000)](http://www.fasebj.org/cgi/content/full/14/10/1325)]. The resultant
decline of DNA repair associated with decreased apoptosis for DNA damage can contribute
to cancer, and probably to aging.
**rrr correlated with Maximum Life Span (MLS)**| Correlation of rat-relative repair (rrr)
and Maximum Life Span (MLS) |
**rrr = rat-relative repair (rat DNA−repair = = 1.0)**
The amount of oxidative DNA damage in neurons is likely to be many times
greater than in most other cells. The human brain accounts for only 2%
of total body weight, but 20% of resting oxygen consumption due to the
high metabolic demand required to maintain membrane ion potentials. Neurons
transcribe about 2−4 times as much DNA as do cells from kidney, liver
or spleen. Yet neurons are non-dividing and must last a lifetime.
A profiling of gene expression for stem cells shows enriched expression of
DNA repair genes [SCIENCE; Ramalho-Santos,M; 298:597-600 (2002)].
Even a "wear&tear" theory like DNA damage is subject to
a programmed aging interpretation. In general, DNA repair tends to lag behind DNA damage
to a greater extent in short-lived species, and the amount of lag can constitute the
degree of "programmed aging". A study which correlated maximum lifespan
in a variety of mammalian species found a six-fold difference in the nuclear DNA-repair
activity of mice and men. A graph of DNA-repair activity standardized on the
rat ("rat-relative repair", where rat DNA-repair activity equals 1.0),
showed a direct correlation between rat-relative DNA repair and maximum lifespan
for the species [MECHANISMS OF AGING AND DEVELOPMENT; Cortopassi, GA; 91:211-218 (1996)].
Many of the nuclear DNA (**nDNA**) repair enzymes discussed above are the same as
or similar to the enzymes that repair mitochondrial DNA (**mtDNA**). The main deficiency
in mtDNA repair is the absence of NER enzymes/proteins, but the presence of multiple
copies of mtDNA in each mitochondrion compensates somewhat. The multiple genomes also
makes HR (homologous recombination) more feasible for mtDNA DSB repair.
**Comparison of mtDNA and nDNA Repair Enzymes/Proteins**| Comparison of mtDNA and nDNA Repair Enzymes/Proteins |
Because of the rapid turnover of mitochondria in cells, oxidative
damage to mitochondrial lipids (membranes) and proteins is normally less
of a concern than oxidative damage to mtDNA. But with age, lysosomes
become less efficient at removing defective mitochondria. Oxidative damage
to cardiolipin in the inner mitochondrial membrane reduces oxidative
phosphorylation [GENE; Paradies,G; 286(1):35-41 (2002)], which is
probably an important factor in the declining ATP production by
mitochondria associated with
aging [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Short,KR; 102(15):5618-5623 (2005)](http://www.pnas.org/cgi/content/full/102/15/5618)]. Moreover, the enzymes responsible
for importing DNA repair proteins into the mitochondria become increasingly
defective with age (possibly due to oxidative
damage) [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Szczesny,B; 100(19):10670-10675 (2003)](http://www.pnas.org/cgi/content/full/100/19/10670)].
Healthy adults 65−80 years of age have about 25% higher skeletal
muscle mtDNA 8−oxodG than adults
20−35 [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Short,KR; 102(15):5618-5623 (2005)](http://www.pnas.org/cgi/content/full/102/15/5618)]. Oxidative damage to mtDNA leads
to mtDNA
deletions [[EXPERIMENTAL BIOLOGY AND MEDICINE; Wei,Y; 227(9):671-682
(2002)](http://www.ebmonline.org/cgi/content/full/227/9/671)]. Clonal expansion of mtDNA deletions with age may ultimately
affect nearly all somatic mtDNA, leading to degenerative disease and the
aging phenotype [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Nekhaeva,E; 99(8):5521-5526 (2002)](http://www.pnas.org/cgi/content/full/99/8/5521)]. Even without oxidative damage mtDNA
mutations and deletions promote apoptosis, leading to tissue degeneration
and aging [SCIENCE; Kujoth,GC; 309:481-484 (2005)]. One mouse model of
"accelerated aging" is based on a mtDNA polymerase knockout that
leads to a 3−5 fold increase in point mutations, as well as to increased
mtDNA deletions [NATURE; Trifunovic,A; 429:417-423 (2004)].
[(return to contents)](#contents)
### XII. TELOMERES AND AGING
Animal cells can be classified as **germ cells** (sperm or egg),
**stem cells** (undifferentiated cells that can differentiate into
functioning body cells) and **somatic cells** (differentiated
functioning body cells). Somatic cells are either non-dividing after
birth (like neurons or muscle cells) or cells that continue to divide
(stem cells and most somatic cells).
One of the most famous experiments in biogerontology was done by Leonard
Hayflick. He observed that embryonic fibroblasts (connective tissue cells)
in tissue culture would divide about 50 times before they ceased dividing.
This 50−division limit (the **Hayflick Limit**) seemed
to be a property of the cell nucleus or DNA.
A human somatic or stem cell has 23 chromosome pairs
(46 chromosomes). Because each chromosome has two ends, there will
be 92 chromosome ends per cell. At the ends of each chromosome is
a long non-functional strand of DNA called a **telomere**. Telomeres
consist of the six-base repeating sequence TTAGGG (2 Thymines,
1 Adenine and 3 Guanines). With each cell division,
some of the telomere is lost because DNA polymerase cannot complete the
5'−end and therefore leaves a
[single-strand 3'−end overhang](http://www.mun.ca/biology/desmid/brian/BIOL2060/CellBiol17/CB17_14.html). But the number of
times that most dividing cells can divide is limited by telomere length.
At conception each human telomere is about 10,000 base pairs long (ie,
about 1,666 TTAGGG repeats), and the typical chromosome is about 13 thousand
times longer (130 million base-pairs). Nine months later, at birth, the
average telomere is half as long as it was at
conception. Telomeres lose an average of eight TTAGGG subunits per cell
division, so half of the telomere length was lost due to the cell
divisions of embryonic development. Human telomeres are less than half
as long as the telomeres of other primates — and the telomeres of
rodents are longer than those of primates [BIOCHEMICAL AND BIOPHYSICAL
RESEARCH COMMUNICATIONS 263:308-314 (1999)]. Telomeres shorten more
rapidly in short-lived mammals & birds than in long-lived
ones [PROCEEDINGS; BIOLOGICAL SCIENCES; THE ROYAL SOCIETY; Haussmann,MF;
270(1522):1387-1392 (2003)].
For some species there is a correlation between maximum lifespan
and the number of fibroblast doublings for that species. Fibroblasts from different
species of mammals display a direct relationship between species lifespan and
number of populations doublings, from 8-11 in mice to 57-67 in
humans [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Rohme,D;
78(8):5009-5013 (1981)](http://www.pnas.org/cgi/content/abstract/78/8/5009)]. Among non-mammals, chickens with a
12−year lifespan show 25 doublings and the Galapagos tortoise with a
175−year lifespan shows 130 doublings. These species not only differ in initial
telomere length, but in the number of telomeres lost at each cell division. But if
maximum lifespan was determined by the Hayflick Limit alone, these species would have
a lifespan 2−3 times greater than what is observed. Mice have very long telomeres,
but have a very short lifespan — showing that long telomeres need not mean high
replicative capacity.
[Flies](http://en.wikipedia.org/wiki/Drosophila_melanogaster) &
[nematodes](http://en.wikipedia.org/wiki/Caenorhabditis_elegans) are
comprised entirely of post-mitotic (non-dividing) cells, which means telomeres are of
no relevance to lifespan in those species. Large animals tend to require more cell
divisions and also live longer, but this does not mean that a large number of divisions
causes longevity.
For humans, the length of the remaining telomere is usually an indicator of how many
divisions a dividing cell has left. One study found an inverse relationship between
telomere length and pulse pressure, indicating a possible direct relationship between
vascular aging and telomere
length [[HYPERTENSION; Jeanclos,E; 36(2):195-200 (2000)](http://hyper.ahajournals.org/cgi/content/full/36/2/195)].
Higher levels of oxidative stress increase the rate
of telomere shortening [TRENDS IN BIOCHEMICAL SCIENCES 27(7):339-344 (2002)].
Once the telomere is gone, functional genetic DNA would be lost with each cell
division. Prior to complete erosion of the telomere a signal is sent to p53 protein
(possibly by ATM protein) to stop the [cell cycle](../health/cancer.html#cellcycle) causing the cell to go into a slow-decaying,
non-replicative state known as **replicative senescence**. Telomeres protect chromosomes
like the plastic cap that prevents shoe-laces from becoming frayed at the ends. Telomeres
have been shown to be seven times more vulnerable to hydroxyl radical oxidation than
similar-sized DNA control fragments, indicating that telomeres could sacrificially protect
coding DNA from oxidative damage [[JOURNAL OF BIOLOGICAL CHEMISTRY; Henle,ES; 274(2):962-971 (1999)](http://www.jbc.org/cgi/content/full/274/2/962)].
**Telomere Complex**| Telomere Complex |
Telomeres are actually a loop-like structure which is associated with an assortment
of proteins (the **shelterin complex**), the most notable of which are the
**Telomeric Repeat-binding Factors**
(**TRF**s). **TRF1** regulates telomere length, assisting the telomerase
enzyme. **TRF2** models the telomere into the **T−loop** structure. TRF2
may be protecting the single-stranded 3'−end overhang from degradation, and
by binding to ATM prevents the ATM-dependent DNA damage
response [[THE EMBO JOURNAL; Blasco,MA; 24(6):1095-1103 (2005)](http://embojournal.npgjournals.com/cgi/content/abstract/21/10/2383)]. Loss of
TRF2 from telomeres directly signals apoptosis [SCIENCE; Karlseder,J;
283:1321-1325 (1999)]. TRF2 stimulates the helicase activity of both **WRN** (of
Werner's Syndrome) and **BLM** (of Bloom Syndrome), which may play a role in telomere
maintenance [[JOURNAL OF BIOLOGICAL CHEMISTRY; Opresko,PL; 277(43):41110-41119
(2002)](http://www.jbc.org/cgi/content/full/277/43/41110)]. **Ku proteins** (normally active in double-strand
break repair) prevent aberrant telomere-telomere fusions. **Tankyrase** is a
**PARP** — Poly (Adenosine diphosphate-Ribose) Polymerase — which can ADP-ribosylate
TRF1, thereby removing it from DNA and allowing telomerase lengthening of the
telomere [SCIENCE; Pirrotta,V; 299:528-529 (2003)]. TRF2 is regulated by
PARP−2 [[MOLECULAR AND CELLULAR BIOLOGY; Dantzer,F; 24(4):1595-1607 (2004)](http://mcb.asm.org/cgi/content/full/24/4/1595)].
Germ cells, stem cells and "immortalized" cancer cells contain an enzyme
called **telomerase** that replaces lost telomeres, thus preventing them
from experiencing a Hayflick Limit.
Telomerase is a **reverse transcriptase**, meaning an enzyme that makes DNA
from an RNA template (the reverse of normal transcription which uses DNA as the
template for making RNA). In human germ cells or 85% of cancer cells
**h**uman **TE**lomerase **R**everse **T**ranscriptase (**hTERT**)
and an RNA template are sufficient conditions for the creation of new telomeres. Because
most cells normally express the RNA template, derepression of hTERT is the critical step
for acquiring telomerase activity. Defects in proteins required to maintain telomere
function can also lead to chromosome instability and cancer [EXPERIMENTAL GERONTOLOGY
36:1619-1637 (2001)]. Telomerase expression can actually make cells more resistant to
apoptosis induced by oxidative stress [FEBS LETTERS; Ren,J; 488:133-138 (2001)].
Mice show no reduction of somatic cell telomere length with age [NATURE 347:400-402 (1990)]
thanks to active somatic telomerase [SCIENCE 291:872-875 (2001)]. Telomeres in
mouse stem cells do, however, shorten with age, possibly leading to decreased regenerative
capacity [[GENES & DEVELOPMENT; Flores,I; 22(5):654-667 (2008)](http://genesdev.cshlp.org/content/22/5/654.long)].
Despite the apparent absence of somatic cell telomere shortening, most
mouse somatic cells stop dividing after only 10−15 doublings.
Possibly, in spite of the ultra-long
telomeres on most chromosomes, a single chromosome with a short telomere could induce
senescence [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Mark,J;
94(14):7423-7428 (1997)](http://www.pnas.org/cgi/content/full/94/14/7423)]. But mouse cells can become senescent despite being
telomerase-positive. Nonetheless, transgenic mice with constitutively expressed TERT
and enhanced expression of tumor-suppressor genes (to provide cancer resistance) have
shown extended mean lifespan and reduced signs of aging [CELL; Tomas-Loba,A;
135(4):609-622 (2008)]. A study of 15 rodent species showed an inverse relationship
between telomerase activity and body mass, but no relationship between telomerase
activity and lifespan [[AGE; Gorbunova,V; 30(2-3):111-119 (2008)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527635/)].
Telomerase knockout mice (mice for whom the telomerase gene has been removed
or "knocked-out") can sometimes maintain telomere length by a mechanism
known as **A**lternative **L**engthening of **T**elomeres (**ALT**).
ALT can also occur in a human cell, but it is ten million times more likely to
occur in a mouse cell [NATURE MEDICINE 6(8):849-851 (2000)]. ALT may be induced by
p53 perturbations at
telomeres [[MOLECULAR AND CELLULAR BIOLOGY; Zaineb,R; 24(13):5967-5977 (2004)](http://mcb.asm.org/cgi/content/abstract/24/13/5967)]
or related to DNA repair at the site of the telomere.
**PML bodies** are donut-shaped protein aggregates in the nucleus containing
**PML** (ProMyelocyclic Leukemia) protein along with other proteins such as pRb.
PML bodies are suspected to normally play a role in tumor suppression. But in
immortalized telomerase-negative ALT cells an aberrant form of PML bodies occur
which contain telomeric DNA, telomere-binding proteins TRF1 & TRF2 and the
Rad51 & Rad52 proteins that are normally active in homologous recombination repair
of double-stranded DNA
breaks [[CANCER RESEARCH; Yeager,TR; 59(17):4175-4179 (1999)](http://cancerres.aacrjournals.org/cgi/content/full/59/17/4175)].
Extrachromosomal telomeric repeats found in the PML bodies can serve as templates
for homologous recombination of
telomeres [[CANCER RESEARCH; Yeager,TR; 59(17):4175-4179 (1999)](http://cancerres.aacrjournals.org/cgi/content/full/59/17/4175)].
If cells continue to divide after having lost their telomeres
(ie, beyond the Hayflick Limit of about 50 cell divisions),
they not only become malfunctional due to lost genes, but the
chromosome ends start sticking to other chromosomes — increasing the
number of abnormalities. Typically a cell will invoke apoptosis
("cell suicide") or other or become senescent (stop the
cell cycle) to prevent the cell from dividing or
becoming cancerous. The Hayflick Limit itself may be a means of
preventing cancer [[SCIENCE; Campisi,J; 309:886-887 (2005)](http://www.ncbi.nlm.nih.gov/pubmed/16081723)].
For those who believe that telomeres are a biological clock
that cause aging by shortening, there has been the hope that human
aging can be stopped by somehow adding active telomerase to all
somatic cells. An experiment transfected human somatic cells
with a reverse transcriptase subunit of telomerase thereby forcing the
cells to express telomerase. The cells exhibited 20 population
doublings beyond their Hayflick Limit and continued to exhibit normal,
healthy and youthful cellular appearance & activity. This experiment
was done not only for fibroblasts, but for retinal epithelial cells and
vascular endothelial cells [SCIENCE 279:334&349 (1998)]. This result
creates hope that it may someday be possible to preserve youth in some tissues by a form of
gene therapy that either induces the expression of telomerase in somatic
cells or adds additional genetic material to cells consisting of an
engineered telomerase superior to the natural form. A person undergoing
such therapy might first take a dose of telomerase destroyers to prevent
any incipient cancers from being nourished by the treatment that would
follow.
Nonetheless, only a few tissues that rapidly proliferate (endothelial cells,
immune system cells, etc.) show decreased function with age that could be associated
with telomere shortening. It is no accident that the notable exceptions to the rule
of lack of telomerase in normal somatic cells are immune system
cells [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Broccoli,D;
92(20):9082-9086 (1995)](http://www.pnas.org/cgi/content/abstract/92/20/9082)] and endothelial
cells [[CIRCULATION RESEARCH; Vasa,M; 87(7):540-542 (2000)](http://circres.ahajournals.org/cgi/content/full/87/7/540)].
For endothelial cells, the exhaustion of replicative capacity
is greatest in areas of atherosclerosis — where the rate of cell division has been
accelerated [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA)92(24):11190-11194
(1995)](http://www.pnas.org/cgi/content/abstract/92/24/11190)]. Telomere erosion contributes to defective liver regeneration and accelerated
cirrhosis in chronic liver injury [[SCIENCE; Rudolph,KL; 287:1253-1258 (2000)](http://www.ncbi.nlm.nih.gov/pubmed/10678830)].
In one study, for a sample of 143 normal people over age 60 having
shorter telomeres the chance of death was more than 3 times greater than average for
heart disease and more than 8 times graater for infectious diseases, but there was
no increased risk for cancer [THE LANCET; Cawthon,RM; 361:393-395 (2003)]. For
males, telomere erosion has been correlated with unhealthy, pro-aging habits such
as smoking, waist circumference, low physical activity and low fruit/vegetable
intake [[AGING CELL; Bekaert,S; 6(5):639-647 (2007)](http://www.ncbi.nlm.nih.gov/pubmed/17874998) and
[AGING CELL; Huda,N; 6(5):709-713 (2007)](http://www.ncbi.nlm.nih.gov/pubmed/17725691)]. Rate of
telomere shortening has predicted cardiovascular mortality in the
elderly [[AGING; Epel,ES; 1(1):81-88 (2008)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830080/)]. A study of 175 elderly Swedish
twin-pairs found that the twins with the shortest telomeres (75% of the cohort)
had 3 times the risk of death compared to the 25% with the longest
telomeres [[AGING CELL; Bakaysa,SL; 6(6):769-774 (2007)](http://www.ncbi.nlm.nih.gov/pubmed/17925004)].
Other studies show no relationship between telomere length and morbidity or mortality
in the elderly [AGING CELL; Martin-Ruiz,CM; 4(6):287-290 (2005) and EPIDEMIOLOGY;
Bischoff,C; 17(2):190-194 (2006)].
People don't age or die because their cells aren't dividing. Cells in culture do
not die after they cease dividing — and may survive as well as cells that never divide,
such as neurons & muscle cells.
[(return to contents)](#contents)
### XIII. CELLULAR SENESCENCE AND APOPTOSIS IN AGING
For background on cell cycle function, read
[Cell Cycle Control](../health/cancer.html#cellcycle)
and [Signalling Molecules
and Transcriptions Factors](../health/cancer.html#signalling).
The relationship between cellular aging and the aging of the
whole organism is complex. Cellular "immortality" is
essential for stem cells, but an "immortal" somatic cell
is cancerous.
[**Apoptosis**](http://en.wikipedia.org/wiki/Apoptosis)
(sometimes pronounced ap-ah-TOE-sis — the second
"p" is silent) is programmed cell suicide — a genetically
***controlled cell death*** that causes cells to shrink and be eliminated
without the tissue traumas associated with inflammation that accompanies
***uncontrolled cell death*** ([**necrosis**](http://en.wikipedia.org/wiki/Necrosis)). Whether a cell dies by apoptosis or necrosis
is critically dependent upon the presence or absence of
ATP [[JOURNAL OF EXPERIMENTAL MEDICINE; 185(8):1481-1486 (1997)](http://www.jem.org/cgi/content/full/185/8/1481)].
Apoptosis can benefit
the organism by eliminating defective cells and protecting from
cancer — or be associated with harmful conditions, as in
atherosclerosis and neurogenerative disease. Cellular senescence
(permanent cell cycle arrest) can benefit the organism by reducing
vulnerability to cancer, but may also contribute to aging-associated
tissue deterioration.
| |
| --- |
| Cytochrome−c activates apoptosis |
In apoptosis proteolytic enzymes (notably **caspases** — **C**ysteine
**AS**partase **P**rote**ASES**) begin the process of orderly protein
degradation that culminates in the production of small packages of cellular remnant.
Apoptosis initiated by an extracellular signal (Fas receptor) activates
**caspase 8**, whereas apoptosis due to intracellular damage or distress
activates **caspase 9**. Both caspase 8 and caspase 9 are initiator
caspases which can activate **caspase 3**, the primary effector caspase which
induces apoptosis [JOURNAL OF NEUROCHEMISTRY; Polster,BM; 90(6):1281-1289 (2004)].
The tumor-suppressor protein **p53** can be a potent initiator
of apoptosis, whereas anti-apoptotic
**Bcl−2** is an oncogene because mutations in the gene increase
**Bcl−2** protein expression, thereby protecting cancer cells from apoptosis.
There is a "family" of **Bcl−2** proteins, all of which possess
at least one of four **B**cl−2 **H**omology domains (**BH1** to **BH4**).
The anti-apoptosis subfamily (which includes **Bcl−2**, **Mcl−1** and
**Bcl−xL**) have all of the homology domains, whereas the
pro-apoptotic subfamily (**Bax**, **Bak**, **Bad**, **Bim**, **Bid**, **Bik**,
**PUMA**, **Noxa**, etc.) are all missing **BH1**. **Bim**, **Bad**,
**Bid**, **PUMA** and **Noxa** only contain
**BH3** [SCIENCE; Adams,JM; 281:1322-1324 (1998)]. In response to DNA damage,
**PUMA** (**p**53 **U**pregulated **M**ediator of **A**poptosis) mediates
**Bax** translocation to the
mitochondria [[JOURNAL OF BIOLOGICAL CHEMISTRY; Melino,G; 279(9):8076-8083
(2004)](http://www.jbc.org/cgi/content/full/279/9/8076)]. In response to DNA damage p53 protein can induce apoptosis by increasing
transcription of **BH3**-only proteins [SCIENCE; Villuger,A;
302:1036-1038 (2003)]. Anti-apoptotic members of the **Bcl−2**
family stabilize the outer mitochondrial membrane (preventing cytochrome−c
release) whereas pro-apoptotic members increase permeability of the outer
mitochondrial
membrane [[BMC CELL BIOLOGY; Lutter,M; 2:22-30 (2001)](http://www.biomedcentral.com/content/pdf/1471-2121-2-22.pdf)]. **Bax** and **Bak**
are restrained from permeabilizing the mitochondrial membrane by their association with
the anti-apoptotic subfamily proteins. The **BH3**-only proteins promote apoptosis by
interfering with the association of the anti-apoptotic subfamily proteins with
**Bax** and **Bak** [SCIENCE; Willis,SN; 315:856-859 (2007)], and (in the case
of **Bid** & **Bim**) by directly activating **Bax** & **Bak**) [NATURE;
Gavathiotis,E; 455:1076-1081 (2008)].
If intracelluar Ca2+ is high, **p53** may be bypassed because high mitochondrial
Ca2+ opens the
[Mitochondrial Permeability Transition Pore (**MPTP**)](#MPTP)
causing energy uncoupling (reduced inner membrane proton gradient), increased superoxide
production, reduced ATP production and the release of **cytochrome c** to the
cytosol — which activates caspase 9. Caspase 9 activates caspase 3 and
caspase 7 by forming an **apoptosome** with cytochrome−c and Apoptotic
Protease Activating Factor−1 (APAF−1). Oxidative stress, DNA damage
and cell stress other than high Ca2+ may induce **Bid** protein to
form **Bax/Bak** channels and release of
cytochrome−c [[JOURNAL OF BIOLOGICAL CHEMISTRY; Rostovtseva,TK; 279(14):13575-13583
(2004)](http://www.jbc.org/cgi/content/full/279/14/13575)].
**MAPK families and AP−1**| MAPK families and AP−1 |
**Mitogens** are agents that trigger mitosis (cell division). Growth factors
are mitogens, but stress can be mitogenic as well. Although very active cell proliferation
(mitosis) is essential to growth & development in a young organism, in an older organism
proliferation may often be associated with inflammation. Proliferation in older animals
more easily leads to cancer (short-lived invertebrates usually have post-mitotic cells).
Mitogens generally act at cell surfaces, and cell signalling resulting from surface
stimulation is by **Mitogen Activated Protein Kinases** (**MAPKs**). (A **kinase**
is an enzyme that transfers a phosphate group from ATP, GTP, ADP, etc, to an enzyme,
thereby activating the enzyme. A **phospatase** does the opposite, inactivating enzymes
by removing a phosphate group.) **MAPK** pathways are typically a series of kinases
that activate other kinases.
There are three families of **MAPKs**: (1) Extracellular signal-Regulated
Kinases (**ERKs**), (2) c−Jun N−terminal Kinases (**JNKs**) and
(3) the **p38** family of kinases. The **ERK** family responds to growth factors, resulting
in proliferation & differentiation, whereas the other two families respond to a
variety of stresses or inflammatory cytokines that can lead either to apoptosis or to
proliferation — depending on the tissue & stimulation. The most important inflammatory
kinase is **p38**. Activator Protein−1 (**AP−1**, a regulator of cell survival
and proliferation) is a transcription factor activated by either **ERK** or **JNK**.
**AP−1** can be pro-apoptotic or anti-apoptotic, but is most often anti-apoptotic
(in association with DNA-repair). ATM loss leads to JNK-mediated **AP−1**
stress [[JOURNAL OF BIOLOGICAL CHEMISTRY; Weizman,N; 278(9):6741-6747 (2003)](http://www.jbc.org/cgi/content/full/278/9/6741)].
**Senescent cells** (cells that no longer proliferate or divide
in response to growth factors or mitogens) can function like
normal cells, but display a number of distinctive characteristics.
Some of these characteristics, such as increased free radical production,
increased oxidative damage, increased glycation damage and reduced
heat shock protein expression may simply be due to the fact that
senescent cells are usually "old". Senescent cells completely lack
**H1** histone (the histone which causes second-order compacting
of chromatin) and contain transcriptionally silent heterchromatic foci
which are believed to repress proliferation
genes [[JOURNAL OF CELL BIOLOGY; Funayama,R; 175(6):869-880 (2006)](http://jcb.rupress.org/cgi/content/full/175/6/869)].
**Ras/Raf/MEK/ERF Pathway**| Ras/Raf/MEK/ERF Pathway |
But the accumulation of
defective proteins may be partially due to a genetic
down-regulation of proteasome activity associated with the senescent
phenotype [[JOURNAL OF BIOLOGICAL CHEMISTRY; Chondrogianni, N;
278(30):28026-28037 (2003)](http://www.jbc.org/cgi/content/full/278/30/28026)]. Although Growth Factors (**GF**s) can still activate the
Ras/Raf/MEK/ERK pathway in senescent cells, the **ERK** subgroup of **MAPKs**
fail to enter the nucleus, ***c−fos*** induction
is reduced and Activator Protein−1 (**AP−1**) transcription factor is far less
capable of binding to DNA. AP−1 activity as a regulator of cell survival —
proliferation is highly influenced by the AP−1
consitituents [[JOURNAL OF CELL SCIENCE; Hess,J; 117(Pt 25); 5965-5973 (2004)](http://jcs.biologists.org/cgi/content/full/117/25/5965)].
Depending on the influence of other transcription factors,
**c−fos** can cause cellular proliferation, differentiation or apoptosis. Serum
Response Elements (**SRE**s) regulate c−fos expression, which is
activated by the Ternary Complex Factor (**TCF**) transcription factors
that cannot bind to SRE without Serum Response Factor (**SRF**). The
**c−Jun** protein is activated by the Jun Kinase (**JNK**) MAPKs. JNK activity
is most stimulated by UV light, whereas ERKs are most strongly stimulated by growth
factors [[JOURNAL OF BIOLOGICAL CHEMISTRY; Karin,M; 270(28):16483-16486 (1995)](http://www.jbc.org/cgi/content/full/270/28/16483)].
Increased expression of c−Jun due to ultraviolet light leads to AP−1
induction of metalloproteinases (collagenases) that contribute to "photoaging"
of skin [[JOURNAL OF CLINICAL INVESTIGATION; Fisher,GJ; 101(6):1432-1440 (1998)](http://www.jci.org/cgi/content/full/101/6/1432)].
Senescent cells are resistant to apoptosis, unlike the postmitotic neurons that
apoptotically contribute to neurodegeneration. Senescent cells are not only
more sensitive to cell injury, they have larger nuclei and less regular
shape. Senescent fibroblasts secrete metalloproteinases that degrade the
collagen matrix secreted by normal fibroblasts. Senescent fibroblasts
also secrete inflammatory cytokines, such as InterLeukin−1 (IL−1).
Resistance of aging cells to apoptosis may be due to a decline in apoptotic protein
function rather than cell senescence [NATURE MEDICINE; Suh,Y; 8(1):3-4 (2002)].
[Caloric Restriction with Adequate
Nutrition](../calories/calories.html) (CRAN) increases rat liver cell apoptosis, particularly for pre-cancerous
cells [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA) 91(21):9995-9999
(1994)](http://www.pnas.org/cgi/content/abstract/91/21/9995)]. Normally reduced proteolysis by proteasomes allows p53 accumulation to
induce apoptosis [[JOURNAL OF BIOLOGICAL CHEMISTRY; Lopes,UG; 272(20):12893-12896 (1997)](http://www.jbc.org/cgi/content/full/272/20/12893)],
but the mechanisms become more dysfunctional with aging. In senescent cells proteasome
activity declines even more rapidly, resulting in a faster accumulation of undegraded
protein products [[THE FASEB JOURNAL; Sitte,N; 14(15):2495-2502 (2000)](http://www.fasebj.org/cgi/content/full/14/15/2495)].
One could easily imagine that the accumulation of increasing numbers
of senescent cells within tissues would contribute to aging of tissues
& organs. Although this appears to be the case in diabetics and
progeria victims (Werner's Syndrome, Down's Syndrome and childhood
progeria), it has not been demonstrated for fibroblasts of "healthy"
persons [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Cristofalo,VJ;
95(18):10614-10619 (1998)](http://www.pnas.org/cgi/content/full/95/18/10614)]. Only a
minority of fibroblasts are senescent in the healthy elderly. On the other
hand, cellular senescence may play a critical role in aging endothelial
cells and the development of
atherosclerosis [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Chang,E;
92(24):11190-11194 (1995)](http://www.pnas.org/cgi/content/abstract/92/24/11190)] and in T−cells.
In mammals, shortening of telomeres leads to senescence in some cells
(*e.g.*, fibroblasts) and apoptosis in other cells (*e.g.*,
T−cells) [[SCIENCE; Karlseder,J; 283:1321-1325 (1999)](http://www.ncbi.nlm.nih.gov/pubmed/10037601)].
The ATM protein kinase which activates p53 protein in response to DNA damage also
activates p53 in response to telomere shortening. Inhibition of ATM in DNA damage
conditions leads to reduced cell senescence and increased
apoptosis [[JOURNAL OF BIOLOGICAL CHEMISTRY; Zhang,X; 280(20):19635-19640
(2005)](http://www.jbc.org/cgi/content/full/280/20/19635)]. Other proteins which participate in NHEJ of double-strand break (DSB)
repair assist in apoptosis induction if DSB repair fails [CELL SIGNALLING;
Abe,T; 20(11):1978-1985 (2008)]. The cell cycle is halted by
**p21Cip1** protein (activated by p53), which initiates cell senescence. But p21
is only expressed transiently. Long-term maintenance of cellular senescence requires
expression of the cell cycle inhibitor **p16INK4a** protein, which
is also induced by p53.
A study of rodent organs found an average 10-fold increase in p16INK4a
expression and an average of 3.5-fold increase in **Arf** expression with age,
concluding that these proteins are biomarkers — and possible effectors —
of both cellular senescence and of mammalian
aging [[JOURNAL OF CLINICAL INVESTIGATION; Krishnamurthy,J;
114(9):1299-1307 (2004)](http://www.jci.org/articles/view/22475)]. Increased p16INK4a expression
with age may lead to increased senescence of pancreatic β−cell
stem cells in non-insulin-resistant type 2
diabetes [[NATURE; Krishnamarthy,J; 443:453-457 (2006)](http://www.ncbi.nlm.nih.gov/pubmed/16957737)]
— and increased stem cell senescence associated with declining neurogenesis
in some (but not all) areas of the brain [[NATURE; Molofsky,AV; 443:448-452 (2006)](http://www.ncbi.nlm.nih.gov/pubmed/16957738)].
In human T-lymphocytes, p16INK4a expression increases
with age between ages 20 to 80, with twice the increase in
smokers [[SCIENCE; Liu,Y; 8(4):439-448 (2009)](http://www.ncbi.nlm.nih.gov/pubmed/19485966)]. Removal
of p16INK4a-positive senescent cells in mice delayed
the onset of age-related pathologies [[NATURE; Baker,DJ; 479:232-236 (2011)](http://www.ncbi.nlm.nih.gov/pubmed/22048312)].
Mice that were transgenic with extra genes of both p53 and **Arf** (with normal activity
of both) had strong cancer resistance, increased levels of reduced glutathione (GSH)
antioxidant, and lifespan increase of 16% [NATURE; Matheu,A; 448:375-380 (2007)].
Both p16 and p21 act by reducing pRB phosphorylation, thereby preventing expression
of the EF2 transcription factors required for DNA synthesis. Nonetheless,
the p53 and pRb tumor-suppressor proteins make partially independent contributions to
cellular senescence. Exposure of the telomere
[3' overhang](http://www.senescence.info/telomeres.html)
after telomere loop disruption appears to be the critical signal for replicative senescence
because oligonucleotides with this overhang can induce senescence in
fibroblasts [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Li,G;
100(2):527-531 (2003)](http://www.pnas.org/cgi/content/full/100/2/527)].
**Cell Divisons and Cell Senescence**| Cell Divisons and Cell Senescence |
In normal human cells, telomere shortening (typically 50−200 base pairs lost per cell
division) will induce cellular senescence after between
50 to 100 cell divisions (***in vitro*** population doublings),
depending on the cell type. Normal cellular senescence is designated **M1** (**Mortality
Stage 1**). If either p53 or pRb expression is inhibited (eg, through defective genes),
senescence will occur after about ten additional population doublings. If both p53 and pRb
expression is inhibited (eg, by simian virus 40, **SV40**), then about twenty
additional doublings will occur and cells enter **M2** (**Mortality
Stage 2**), also called **crisis**. In contrast to M1 cells (which have short
telomeres of about 4 Kbp, Kilobase pairs), M2 cells have extremely short telomeres
(about 1.5 Kbp), are genetically unstable and usually die quickly [THE EMBO JOURNAL;
Counter,CM; 11(5):1921-1929 (1992)]. Fewer than one in a million cells survive crisis.
Surviving cells nearly always become "immortalized" by telomere expression.
(In contrast to humans, although rats display senescence for fibroblasts, they show no
sign of replicative senescence for glial cells [SCIENCE; Mathon,NF; 291:872-875 (2001)].)
So-called premature cellular senescence can be provoked by various sublethal cellular stresses
such as hydrogen peroxide, ultraviolet irradiation and similarly damaging agents which either
accelerate the number of telomeres lost per division or directly induce DNA damage or both.
Fenton reaction-mediated DNA damage is seven times more likely to occur in telomeres than
elsewhere in a chromosome, probably because of the higher proportion of
guanosines in the telomere
(TTAGGG) [[JOURNAL OF BIOLOGICAL CHEMISTRY; Henle,ES; 274(2):962-971 (1999)](http://www.jbc.org/cgi/content/full/274/2/962)].
In fact, the role of oxidation in telomere shortening is dramatically demonstrated by
the fact that spin-trapping agent PBN treatment of cells can increase their number of
population doublings by as much as
25% [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Chen,Q;
92(10):4337-4341 (1995)](http://www.pnas.org/cgi/content/abstract/92/10/4337)].
But premature cellular senescence can also be induced by agents that are more directly
involved in cell signalling dysfunction, such as ***ras*** oncogene
overexpression [CELL; Serrano,M;88(5):593-602 (1997)], PML protein
overexpression [THE EMBO JOURNAL; Bischof,O; 21(13):3358-3369 (2002)], Transforming
Growth Factor beta (**TGF−ß**) or histone deacetylase
inhibition [[MOLECULAR AND CELLULAR BIOLOGY; Ogryzko,VV; 16(9):5210-5218 (1996)](http://mcb.asm.org/cgi/content/abstract/16/9/5210)].
Stress-induced senescence due to Ras protein requires signalling from the p38 (stress-activated)
form of Mitogen-Activated Protein Kinase (MAPK) and cannot be prevented by hTERT-mediated
telomerase elongation. TGF−ß inhibits telomerase and, like Ras protein, mediates
senescence by p38 MAPK activation. Cellular senscence due to DNA damage can be triggered
by p38 MAPK signalling and does not require ATM
protein [[JOURNAL OF BIOLOGICAL CHEMISTRY; Naka,K; 279(3):2030-2037 (2004)](http://www.jbc.org/cgi/content/full/279/3/2030)].
**TGF−ß and insulin/IGF−1 pathways leading to dauer**| Cell Divisons and Cell Senescence |
Homeostasis and remodeling of the extracellular matrix is mediated in large part through
an interplay of Matrix MetalloProteinases (**MMP**s, collagenase) and Tissue Inhibitors
of MetalloProteinases (**TIMP**s). Senescence of fibroblasts is accompanied by a shift
from matrix synthesizing to matrix degredation associated with increased MMP production and
decline of tissue function. TGF−ß can induce either
apoptosis [[ENDOCRINOLOGY; Bruckheimer,EM; 142(6):2419-2426 (2001)](http://endo.endojournals.org/cgi/content/full/142/6/2419)]
or senescence [[ENDOCRINE-RELATED CANCER; Fleisch,MC; 13(2):379-400 (2006)](http://erc.endocrinology-journals.org/cgi/content/full/13/2/379)]. Peculiarly,
TGF−ß induces TIMP and represses
MMP [[JOURNAL OF BIOLOGICAL CHEMISTRY; Hall,M; 278(12):10304-10312 (2003)](http://www.jbc.org/cgi/content/full/278/12/10304)].
Also peculiar is the fact that MMP production seems to be mediated by the same forkhead
family of transcription factors that are credited with increased longevity in
***C. elegans*** nematode worms due to disruption of
insulin/[IGF1−1](../nutrceut/GH_IGF1.html)-like
signalling [[JOURNAL OF BIOLOGICAL CHEMISTRY; Mawal-Dewan; 277(10):7857-7864 (2002)](http://www.jbc.org/cgi/content/full/277/10/7857)]
and that mutations in the TGF−ß pathway can induce ***C. elegans***
dauer formation, but (unlike mutations in the insulin/IGF−1 pathway) do not extend
adult nematode lifespan [[BMC DEVELOPMENTAL BIOLOGY; Liu,T; 4:11 (2004)](http://www.biomedcentral.com/1471-213X/4/11)].
(See [LONGEVITY GENES (FLIES & WORMS)](#longevity) for
more about ***C. elegans*** dauer formation and lifespan extension
associated with insulin/IGF−1 signalling.)
Both p53 and pRB participate in apoptosis as well as senescence. Whereas p53 induces
apoptosis in response to DNA damage, loss of pRB leads to apoptosis and deregulated
cell proliferation [CURRENT OPINION IN GENETICS & DEVELOPMENT; Hickman,ES;
12(1):60-66 (2002)]. The p53 protein not only induces apoptosis by increasing gene
expression of Bax, Bak and a number of other proteins [BIOCHEMICAL AND
BIOPHYSICAL RESEARCH COMMUNICATIONS; Michalak,E; 331(3):786-798 (2005)], but p53 also
directly activates Bax protein in the cytoplasm [SCIENCE; Chipuk,JE; 303:1010-1014
(2004)].
What is the relationship between cellular senescence, apoptosis, cancer and aging?
Apoptosis in development is the reason humans do not have webbed hands. In the developing
nervous system cell proliferation accompanies apoptosis with "survival of the
fittest" synaptic connections. The great majority of T−lymphocytes produced are
eliminated by apoptosis, an important defense against auto-immune disease. T−cells
express a **Fas** (CD95) receptor which mediates an apoptotic signal that bypasses
nuclear transcription and directly activates proteases, thus terminating the immune response.
Fas receptor expression on T−cells increases with aging, enhancing the susceptibility
of T−cells to apoptosis [CELL AND TISSUE RESEARCH; Higami,Y; 301(1):125-132
(2000)].
A youthful, healty organism has efficient cell-cycle control and can thereby resist
undesirable apoptosis while efficiently using apoptosis when needed. Cells having DNA defects
or mitochondria producing excessive free radicals can be eliminated by apoptosis and
macrophages without causing inflammation. Aged cells with less effective cell-cycle control
will less readily apoptose when defective, but will more often dysfunctionally apoptose. High
levels of apoptosis in aged tissues result in tissue degeneration. Accumulated free radical,
glycation and other forms of cellular damage lead increasingly to dysfuncional cell-cycle
control with age. Some of those immersed in genetic paradigms of aging assert that
CRAN ([Caloric Restriction with
Adequate Nutrition](../calories/calories.html)) "up-regulates" apoptosis in cancer cells while
"down-regulating" apoptosis in normal cells. A more reasonable explanation
might be that by reducing oxidative stress & glycation, CRAN maintains youthful
cell-cycle control.
Apoptosis may be protective in some tissues,
whereas cellular senescence may be more protective against cancer in other tissues.
Reduction of nitric oxide synthesis with aging reduces the nitric oxide inhibition of
endothelial cells apoptosis — leading to a worsening of atherosclerotic disease.
Endothelial cells have a high rate of telomere loss and senescent endothelial cells
contribute to atherosclerosis by the release of pro-inflammatory
cytokines [[CIRCULATION; Minamino,T; 105(13):1541-1544 (2002)](http://circ.ahajournals.org/cgi/content/full/105/13/1541)].
The "longevity gene" SIRT1 gene
silencing protein increases cell cycle arrest by FOXO transcription factor while
inhibiting FOXO's induction of apoptosis [SCIENCE; Brunet,A; 303:2011-2015 (2004)].
The **p53 protein** arrests cell growth
([cell cycle arrest](../health/cancer.html#cellcycle))
& triggers cell suicide (apoptosis) — typically as a response to DNA damage.
Normally p53 protein induction of cellular senescence (halted growth cycle) is regarded
as a defense against cancer, but SIRT1 inhibition of p53-mediated apoptosis and
cell senescence is presumed to be life-extending by allowing for cell repair.
Cellular senescence has been called an "antagonistic pleiotropic trait" that
benefits young organisms at the expense of harm to older organisms. An exaggerated example
of this may be **p53+/m** mutant mice, which show enhanced p53 protein
activity. Although the mutant mice show an accelerated aging phenotype and only live
80% as long as normal mice, cancer is exceedingly rare in these
mutants [NATURE; Tyner,SD; 415:45-53 (2002)]. The mice support the views that cellular
senescence/apoptosis is a defense against cancer and that cellular senescence/apoptosis
can lead to senescence (aging)
of the organism as a whole. Cellular senescence may also be antagonistically pleiotropic
due to the secretions of senescent cells, which have been shown to promote cancer growth in
surrounding tissues [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Krtolica,A;
98(21):12072-12077 (2001)](http://www.pnas.org/cgi/content/full/98/21/12072)].
Werner's Syndrome (reputedly the segmental progeria most resembling accelerated aging)
is often characterized as a disease of accelerated telomerase functioning and cellular
senescence. In contrast to normal human fibroblasts which senesce after about
50 population doublings, Werner's patients' fibroblasts usually senesce after about
20 doublings — with longer than normal telomeres. The WRN protein, which is defective
in Werner's patients is a **helicase** (enzyme that unwinds double helical regions in DNA
and RNA) and an **exonuclease** (enzyme that catalyzes hydrolytic removal of nucleotides
from the end of DNA and RNA).
Werner's patient fibroblasts are resistant to apoptosis. The high proportion of sarcomas
in those patients may be due to the promotion of transformation of the non-senescent
cells by the proteases & cytokines created by the many senescent cells. Werner's
Syndrome is not simply a model system of the effect of a high proportion of senescent cells
because defective DNA repair plays such a prominent role in the disease.
Transgenic mice that have defective repair of mitochondrial DNA will have reduced lifespan,
increased apoptosis and display an "accelerated aging"
phenotype [[SCIENCE; Kujoth,GC; 309(5733):481-484 (2005)](http://www.sciencemag.org/cgi/content/full/309/5733/481)]. The mice show no sign of
oxidative stress or increased free radical production.
In general, apoptosis can be described as being **signal-induced** or
**damage-induced**. **Signal-induced apoptosis** is essential for the precision
elimination of undesirable cells following proliferation of many cell types, including
clonal expansion of T−cells. Well-controlled apoptosis is a feature of an efficient
immune system. **Damage-induced apoptosis** is a major factor in neurodegeneration,
although the process undoubtedly becomes increasingly necrotic. The same may be true for
macrophages that die in atherosclerotic plaques. If the immune system induces apoptosis
in cancer cells, it could involve both forms of apoptosis. There is a decrease in both
kinds of apoptosis with age, as cellular signalling and regulation (including apoptotic
regulation) becomes less efficient. A tissue deprived of many cells because of a high level
of apoptosis may display the "aged phenotype" as much as a tissue composed
largely of senescent cells that are too defective to undergo apoptosis.
A [biomarker](#biomarkers) of cell senescence would facilitate
the identification and study of senescent cells, as well as the targeting for destruction
of such cells. The most promising candidate biomarker, **ß-galactosidase**, is
elevated in replicative senescence and can quantitatively estimate replicative age
***in vitro***. But cellular ß-galactosidase also is present in immortal cells
and can be induced by subjecting cells to hydrogen peroxide [EXPERIMENTAL CELL
RESEARCH; Severino,J; 257:162-171 (2000)].
It has been suggested that reprogramming cells to apoptose rather than senesce may
be a means to reduce cancer and eliminate one cause of aging.
[(return to contents)](#contents)
### XIV. "ACCELERATED AGING" DISEASES
(SEGMENTAL PROGERIA)
"Accelerated aging" is distinct from accelerated mortality
because "accelerated aging" diseases exhibit an elderly
phenotype and increased disposition to aging-associated diseases such
as [cancer](../health/cancer.html)
and [Alzheimer's Disease](./Alzheimer.html).
Too often, however, "accelerated aging" is equated with
increased disposition to aging-associated diseases in the absence of an
elderly phenotype). High blood pressure and AIDS accelerate mortality
without exhibiting an elderly phenotype. Without objective
[biomarkers of aging](#biomarkers) the "elderly
phenotype" is open to dispute.
No disease condition displays all symptoms of accelerated aging.
Diseases that resemble certain aspects of accelerated aging are
known as **segmental progerias**, because of the "segments"
of aging in each disease condition. If aging is due to a variety of cellular
and molecular damages, segmental progerias may represent subsets of those
damages.
Segmental progerias primarily are diseases of defective
DNA-repair, [although diabetics also
show many features of accelerated aging](#glycation). Defects in
Base Excision Repair (BER), however, are generally too lethal to manifest as accelerated
aging [SCIENCE; Hasty,P; 299:1355-1359 (2003)].
([Genomic instability syndromes](http://www.rndsystems.com/mini_review_detail_objectname_MR04_GenomicInstability.aspx) are not necessarily progerias.)
It has been proposed that segmental progerias result from decreased cytotoxic DNA
damage repair or from an exaggerated response to DNA damage signals — whereas
cancers result from decreased mutagenic DNA damage repair or from an impaired
response to DNA damage signals — with excision repair mainly effective against
cancer and transcription-coupled (or interstrand cross-link) repair mainly facilitating
longevity [CURRENT OPINION IN CELL BIOLOGY; Mitchell,JR; 15(2):232-240 (2003)].
Progeroid syndromes have been associated with NER and DSB repair, but not with BER
or MMR [JOURNAL OF INTERNAL MEDICINE; Lombard,DB; 263(2):128-141 (2008)]. In both
human patients and mouse models only some DNA repair defects show accelerated aging,
namely the TCR subtype of NER and defects to NHEJ genes. The GGR subtype of NER
mainly results in increased carcinogenesis and "photo-aging", although
there is neurodegeneration. BER defects are generally lethal [SCIENCE; Hasty,P;
299:1355-1359 (2003)], but SIRT6 (which facilitates BER by an unknown mechanism)
knockout mice do show an accelerated aging phenotype (including loss of subcutaneous
fat and decreased bone density) during the few weeks in which they are able to
survive [Mostoslavsky, 2006].
**Werner's syndrome** (**WS**) is associated with early onset of very many age-related
diseases and most closely represents accelerated aging of any of the segmental
progerias. About two-thirds of WS victims are Japanese (attributed to inbreeding).
WS is due to a defect or deletion of a single gene
(**WRN**), resulting in defects of both telomeres and DNA
repair [[MOLECULAR AND CELLULAR BIOLOGY; Du,X; 24(19):8437-8446 (2004)](http://mcb.asm.org/cgi/content/full/24/19/8437)].
The **WRN gene** is
a member of the **helicase** family that causes DNA to unwind, which is a requirement for
most forms of DNA repair. Defective WRN protein results in a reduction of p53-mediated
apoptosis. There is an accelerated rate of somatic mutations, particularly
deletions [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Fukuchi,K;
86(15):5893-5897 (1989)](http://www.pnas.org/content/86/15/5893)], although defects are also probable in BER and
NHEJ [MECHANISMS OF AGEING AND DEVELOPMENT; Kusumoto,R; 128(1):50-57 (2007)].
Defective homologous recombination is believed to
be the primary reason for the chromosomal abnormalities of WS
victims [[GENES & DEVELOPMENT; Prince,PR; 15(8):933-938 (2001)](http://genesdev.cshlp.org/content/15/8/933)
and [MOLECULAR AND CELLULAR BIOLOGY; Saintigny,Y; 22(20):6971-6978
(2002)](http://mcb.asm.org/cgi/content/full/22/20/6971)]. Defective recombination leads to genomic instability and thus
greatly increased risk of cancer, particularly sarcomas (the relative incidence of mesenchymal
cell cancer compared to epithelial cell cancer is ten times
normal) [[CANCER EPIDEMIOLOGY, BIOMARKERS & PREVENTION; Goto,M;
5(4):239-246 (1996)](http://cebp.aacrjournals.org/cgi/reprint/5/4/239)]. WRN has been described as a tumor-suppressor
gene because epigenetic silencing of WRN increases chromosomal
instability and because tumor-types match those of other tumor-suppressor
gene defects [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Agrelo,R; 103(23):8822-8827 (2006)](http://www.pnas.org/cgi/content/full/103/23/8822)]. But WRN also acts as a tumor suppressor
by its facilitation of p53-mediated
apoptosis [[GENES & DEVELOPMENT; Spillare,EA; 13(11):1355-1360 (1999)](http://genesdev.cshlp.org/content/13/11/1355)].
Unlike carcinomas, mesenchymal
tumors primarily maintain telomeres by the ALT
mechanism [[JOURNAL OF CELL SCIENCE; Multani,AS; 120(Pt 5):713-721
(2007)](http://jcs.biologists.org/cgi/content/full/120/5/713)]. Although mesenchymal malignancies predominate for both mice
& WS victims, WRN knockout mice show no sign of accelerated
aging despite reduced cellular proliferation
capacity [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Lebel,N; 95(22):13097 (1998)](http://www.pnas.org/cgi/content/full/95/22/13097)]. Whereas normal human
fibroblasts experience replicative senescence after about 60 divisions, the fibroblasts
of WS patients senesce after about
20 divisions [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Faragher,RGA;
90(24):12030-12034 (1993)](http://www.pnas.org/cgi/content/abstract/90/24/12030)]. The accelerated senescence of fibroblasts from WS
patients is associated with an accelerated accumulation of double-strand
breaks [[JOURNAL OF RADIATION RESEARCH; Ariyoshi,K; 48(3):219-231 (2007)](http://www.jstage.jst.go.jp/article/jrr/48/3/48_219/_article)].
Telomeres are of
normal length initially, but shorten at an abnormally high rate, resulting in many so-called
senescent cells (creating a model system for the study of the senescent cell phenotype).
Telomere repair is reduced, as is MisMatch Repair (MMR), TCR Base Excision Repair (BER)
and double-strand break repair of DNA.
Transcription of mRNA by RNA polymerase II from DNA is roughly half
as efficient in WS cells compared to normal
cells [[MOLECULAR BIOLOGY OF THE CELL; Balajee,AS; 10(8):2655-2668
(1999)](http://www.molbiolcell.org/cgi/content/full/10/8/2655)]. The disease first becomes evident in the
late teens or early 20s, and typically results in death by age 50 by cardiovascular
disease. Osteoporosis, premature hair graying, alopecia, high blood pressure, stroke,
cataracts, severe atherosclerosis, and type 2 diabetes are extremely
common [MECHANISMS OF AGING & DEVELOPMENT; Goto,M; 98(3):239-254 (1997)].
Many of these effects may be due to increased levels of the inflammatory cytokines
produced by aging and senescent cells [EXPERIMENTAL GERONTOLOGY; Kumar,S;
28(6):505-513 (1993) and REJUVENATION RESEARCH; Davis,T; 9(3):402-407 (2006)].
Conversely, proinflammatory cytokines have been shown to induce cellular
senescence [FREE RADICAL RESEARCH; Sasaki,M; 42(7):625-632 (2008)].
Abnormally high levels of collagenase from senescent fibroblasts leads to loss of skin
elasticity and to skin wrinkling. Experimentally produced cellular senescence in
rat arteries results in an atherosclerotic phenotype matching that seen in WS and
normal aging [[CIRCULATION; Minamino,T; 108(18):2264-2269 (2003)](http://circ.ahajournals.org/cgi/content/full/108/18/2264)], which
supports the general contention that cell senescence contributes significantly
to the normal aging phenotype. At a much faster rate than is often seen in normal
aging, WS victims accumulate visceral fat, develop high levels of the plasma
[cytokine](http://en.wikipedia.org/wiki/Cytokine)
[TNF−α](#inflame), develop insulin resistance
and show a [metabolic
syndrome](../health/MacroNut.html#syndrome) profile, but without being
obese [[DIABETES CARE; Yokote,K; 27(10):2562-2563 (2004)](http://care.diabetesjournals.org/cgi/content/full/27/10/2562)].
The carbonyl content of proteins in
WS victims increases exponentially with age at a much higher rate than normal.
Microarray profiling of 6,912 human fibroblast genes showed 91% of the
genes were common to WS and aging cells, 6% were unique to normal aging
and 3% were unique to
WS [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Kyng,KJ; 100(21):12259-12264 (2003)](http://www.pnas.org/cgi/content/full/100/21/12259)].
But WS victims show no increased tendency for neurodegeneration, prostate
problems or Alzheimer's Disease — and the immune system remains normal. The
progeroid symptoms of WS have been attributed to both increased cellular
senescence [SCIENCE; Kipling,D; 305:1426-1431 (2004)] and increased
apoptosis [[MOLECULAR BIOLOGY OF THE CELL; Pichierri,P; 12(8):2412-2421 (2001)](http://www.molbiolcell.org/cgi/content/full/17/4/1583)].
In **Hutchinson-Gilford Progeria Syndrome** (**HGPS**, "childhood progeria",
in contrast to the "adult progeria" of Werner's syndrome)
a child is born with abnormally short telomeres. Childhood progeria occurs
once per 4−8 million births. Victims are characterized by short stature, early
hair loss, cardiovascular problems (stroke and coronary dysfunction are common)
and an elderly facial phenotype, but normal cognition and immune function, and
no disposition to cancer [AMERICAN JOURNAL OF MEDICAL GENETICS (PART A);
Hennekam,RCM; 140(23):2603-2624 (2006)].
The disease is caused by a point mutation in the gene for
**lamin A**, a filament protein in the nuclear matrix and nuclear lamina
that is required for DNA replication and nuclear organization. The point mutation
results in a **prelamin A** protein called **progerin** that cannot be
converted to lamin A because it is missing 50 amino acids. Progerin
retains a hydrophobic
[farnesyl](http://en.wikipedia.org/wiki/Farnesol) group
(normally cleaved by the protease ZMPSTE24) which causes it to be highly membrane-associated.
The intranuclear scaffold
formed by lamins may facilitate transcription, replication and DNA repair [NATURE
MEDICINE; Liu,B; 11(7):780-785 (2005)]. Disruption of nuclear lamin organization
inhibits mRNA transcription (RNA polymerase II activity) in mammalian
cells [[THE JOURNAL OF CELL BIOLOGY; Spann,TP; 156(4):603-608 (2002)](http://jcb.rupress.org/cgi/content/full/156/4/603)].
DSBs accumulate in HGPS and ZMPSTE24-deficient
cells, where DSB-repair is apparently blocked by accumulation of mis-localized XPA
protein at the damage
site [[THE FASEB JOURNAL; Liu,Y; 22(2):603-611 (2008)](http://www.fasebj.org/cgi/content/full/22/2/603)].
Cells with the lamin A mutation show an
impaired ability to form foci for the recruitment of DNA repair
proteins during DNA replication, resulting in defective homologous
recombination [NATURE MEDICINE; Liu,B; 11(7):780-785 (2005) and
[JOURNAL OF CELL SCIENCE; Manju,K; 119(Pt 13):2704-2714 (2006)](http://jcs.biologists.org/cgi/content/full/119/13/2704)
and DNA REPAIR; Paulson;RD; 6(7):953-966 (2007)].
At age 5 the telomeres of a
Hutchinson-Gilford syndrome child are about as long as those of a very elderly person.
HGPS patient cells show loss of epigenetic
control [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Shumaker,DK;
103(23):8703-8708 (2006)](http://www.pnas.org/cgi/content/full/103/23/8703)]. A study which compared HGPS patient cells with the skin
cells from young & elderly human subjects found similar defects in the HGPS & elderly
cells, including down-regulation of certain nuclear proteins, increased DNA damage
and demethylation of H3 histone leading to reduced heterochromatin, suggesting
that lamin A defects contribute to normal aging [SCIENCE; Scaffidi,P;
312:1059-1063 (2006)]. Nuclear levels of phosphorylated **H2AX** — which
recruits DNA repair proteins to sites of DNA damage [SCIENCE; Celeste,A; 296:992-997
(2005)] — is more than three times higher in fibroblasts from old
(81 to 96 years) as compared to young (3 to 11 years) normal humans [SCIENCE;
Scaffidi,P; 312:1059-1063 (2006)], comparable to what is seen in HGPS cells [NATURE
MEDICINE; Liu,B; 11(7):780-785 (2005)].
Most often these children die of myocardial infarction or
stroke (average age of death is 13). The premature atherosclerosis is without the
usual causes association with high blood pressure or high blood cholesterol. Progestin
preferentially accumulates in the nuclei of vascular smooth muscle and endothelial
cells causing the cells to senesce or become
apoptotic [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
McClintock,D; 103(7):2154-2159 (2006)](http://www.pnas.org/cgi/content/full/103/7/2154)]. Carbonyl content of protein rises
more rapidly with age than in any of the other segmental progerias.
These children do not have the high rates of presbyopia, cataracts, osteoporosis or
[Alzheimer's Disease](../lifeext/Alzheimer.html)
often seen in the elderly. Like WS, HGPS is primarily a disease of proliferative
tissues characterized by high rates of cellular senescence and
apoptosis [EXPERIMENTAL GERONTOLOGY; Bridger,JM; 39(5):717-724 (2004)].
**Bloom's syndrome**, like Werner's syndrome, is due to a defective
helicase-type protein, in this case **BLM** — leading to chromosome
aberrations [[NUCLEIC ACIDS RESEARCH; Brosh,RM; 35(22):7527-7544 (2007)](http://nar.oxfordjournals.org/cgi/content/full/35/22/7527)].
The disease is most common in Ashkenazi Jews (descendents of Eastern European
Jews) due to intensive inbreeding. Victims are small at birth and rarely
grow to be taller than 5 feet. Intelligence is usually normal. Photosensitivity
causes the face to be red. Approximately 10% of victims have type 2 diabetes.
Immunodeficiency leads to recurrent severe infections of the respiratory tract
and ear. Women have reduced fertility and men are usually completely infertile.
Death is most often due to cancer. If they survive death from leukemia at an average
age of 22, Bloom's victims usually die of solid tumors at an average age of 35.
BLM protein is preferentially expressed in proliferative tissues containing
high levels of telomerase. BLM protein deficiency renders cells highly vulnerable to
p53-induced apoptosis, which is
suggested to contribute to growth retardation. During the S-phase of the cell
cycle BLM protein localizes in the nucleolus where it apparently assists in the
resolution of stalled replication
forks [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Yankiwski,V;
97(10):5214-5219 (2000)](http://www.pnas.org/cgi/content/full/97/10/5214)]. The BLM protein is normally found
mainly in the PML bodies of the nucleus, but when NHEJ
is required to repair DSBs, BLM protein causes rapid
recruitment of BRCA1 protein to the site of
damage [[JOURNAL OF CELL BIOLOGY; Davalos,AR; 162(7):1197-1209 (2003)](http://www.jcb.org/cgi/content/full/162/7/1197)].
The high rate of apoptosis in Bloom's Syndrome victims would be predictive
of an accelerated aging phenotype with reduced cancer, but high proliferation
& decreased genome stability selects for p53 mutations which reduce
apoptosis & foster cancer [[JOURNAL OF CELL BIOLOGY; Davalos,AR; 162(7):1197-1209 (2003)](http://www.jcb.org/cgi/content/full/162/7/1197)].
BLM protein highly co-localizes with telomeres in cells maintaining telomere
length by the ALT mechanism, but not in normal or telomerase-positive
cells [[HUMAN MOLECULAR GENETICS; Stavropoulos,DJ; 11(25):3135-3144
(2002)](http://hmg.oxfordjournals.org/cgi/content/full/11/25/3135)]. Chromosomal breaks and a greatly elevated rate of sister chromatid
exchanges are characteristic features of Bloom's
syndrome [[AMERICAN JOURNAL OF HUMAN GENETICS; German,J; 29(3):248-255 (1977)](http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=868871)].
BLM protein prevents excessive homologous recombination [NATURE;
Wu,L; 426:870-874 (2003)], particularly where
[D−loops](http://en.wikipedia.org/wiki/D-loop)
are formed [[NUCLEIC ACIDS RESEARCH; Bachrati,CZ; 34(8):2269-2279(2006)](http://nar.oxfordjournals.org/cgi/content/full/34/8/2269)].
BLM protein also complexes with the **Rad51** protein in homologous recombination
repair of double-strand DNA
breaks [[JOURNAL OF BIOLOGICAL CHEMISTRY; Braybrooke,JP;
278(48):48357-48366 (2003)](http://www.jbc.org/cgi/content/full/278/48/48357)] and inhibits the exonuclease activity of WRN
protein [[JOURNAL OF BIOLOGICAL CHEMISTRY; von Kobbe,C; 277(24):22035-22044
(2002)](http://www.jbc.org/cgi/content/full/277/24/22035)].
**Down's syndrome** is caused by an extra copy of chromosome 21, the
shortest human chromosome (50-million base-pairs). One birth in 700 is a
Down's baby — most frequently seen in the babies of women giving birth
in their 30s or 40s. The disease accounts for one-third of all cases
of mental retardation in industrialized countries. Down's syndrome victims
have short stature, hearing deficits and features of accelerated aging, which
include hair graying & hair loss and increased tissue
lipofuscin levels. One third of Down's victims have hypothyroidism.
Although the overall cancer incidence may be lower, the incidence of
leukemia is 10 to 20 times higher than normal. Down's syndrome
victims are very vulnerable to infection, due to the rapid shortening
of the telomeres of their leukocytes (white blood cells). Almost all
Down's syndrome victims have
[Alzheimer's Disease](../lifeext/Alzheimer.html)
by age 50, probably
because chromosome 21 carries the amyloid gene. Chromosome 21
also carries Cu/Zn SuperOxide Dismutase gene, resulting in increased
production of hydrogen peroxide (H2O2) which
(without catalase or glutathione peroxidase) can lead to more hydroxyl
radicals. Down's syndrome victims show a 50% increase in cytoplasmic
SOD. Cultured cells transfected with an increased gene dosage of cytoplasmic
SOD show features of cellular senescence mediated by hydrogen
peroxide [[HUMAN MOLECULAR GENETICS; de Haan,JB; 5(2):283-292 (1996)](http://hmg.oxfordjournals.org/cgi/content/full/5/2/283)].
The incidence of diabetes is 5−10 times greater for Down's
syndrome victims than for age-matched controls. Nonetheless, Down's syndrome
victims show no accelerated vulnerability for breast & prostate cancer,
high blood pressure, or osteoporosis.
**[Xeroderma
pigmentosum](http://en.wikipedia.org/wiki/Xeroderma_pigmentosum)** (**XP**) patients show tissue-specific signs of premature aging,
mainly of the skin & eyes ("photoaging"), have a high
incidence of skin cancer (more than a thousand-fold over normal) and have neurological
problems. Although XP victims rarely reach the age of 30, for the most part they
do not display an "accelerated aging" phenotype. XP
is due to compromised Nuclear Excision Repair (NER)
due to defects in any one of seven genes/proteins designated **XPA** to **XPG**.
XPB and XPD are [helicases](http://en.wikipedia.org/wiki/Helicase)
which are part of the NER
[transcription
factor](http://en.wikipedia.org/wiki/Transcription_factor) **TFIIH**. XPC and XPE are proteins that recognize DNA damage.
Patients with defects in XPC (which functions exclusively in GG-NER) do not
suffer the severe neurological disease that can be seen in patients with XPA
defects [DNA REPAIR; Niederhofer,LJ; 7(7):1180-1189 (2008)]. XPF and
XPG are [endonucleases](http://en.wikipedia.org/wiki/Endonuclease).
The XPF-ERCC1 endonuclease functions in both Global Genome Nuclear Excision
Repair (**GG−NER**) and repair of crosslinks between DNA strands. XP can even
be caused by mild mutations of the XPF subunit of the XPF−ERCC1 endonuclease — which is
used to replace pyrimidine dimers. DNA repair capability is particularly
important in the brain because neurons are not replaced, but have high
metabolic demands which subject them to high oxidative stress. For this reason, reduced
repair of oxidative DNA damage is a reasonable explanation for the neurodegeneration
seen in XP patients [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Reardon,JT; 94(17):9463-9468 (1997)](http://www.pnas.org/content/94/17/9463)]. Cells from XP patients with neurodegeneration
show extremely poor NER of free-radical induced bulky DNA
lesions [[JOURNAL OF BIOLOGICAL CHEMISTRY; Brooks,PJ; 275(29):22355-22362 (2000)](http://www.jbc.org/cgi/content/full/275/29/22355)].
Transgenic mice which are null for both XPF & ERCC1 proteins are defective
in both NER and DNA interstrand crosslink repair, which leads to **XFE progeria**.
Defective crosslink repair leads to DSBs in these
mice [[MOLECULAR AND CELLULAR BIOLOGY; Niedernhofer,LJ; 24(13):5776-5787
2004)](http://mcb.asm.org/cgi/content/full/24/13/5776)]. In XFE
progeria there is more cell senescence and more apoptosis, but less mutation and telomere
loss [NATURE; Niedernhofer,LJ; 444:1038-1043 (2006)]. These mice show accelerated
aging, but suppressed carcinogenesis [NATURE; Niedernhofer,LJ; 444:1038-1043 (2006)].
Interstrand crosslink repair necessitates NER followed by HR [THE LANCET
ONCOLOGY; McHugh,PJ; 2(8):483-490 (2001)]. Complicating matters is reduced serum
[IGF1](../nutrceut/GH_IGF1.html), which is believed to
be an adaptive response to DNA damage [NATURE; Niedernhofer,LJ;
444:1038-1043 (2006)].
**Cockayne syndrome** is due to a defective protein which is required
for the Transcription-Coupled Repair (TCR) subtype of Nucleotide Excision
Repair (NER) of DNA. Although newborns appear normal there is early
dwarfism ("cachectic dwarfism"), mental retardation, cataracts,
deafness, photosensitivity, osteoporosis, dental caries, sparse hair and
a senile-like appearance (including a pinched, narrow face and a beaked nose,
due to reduced subcutaneous fat) [PEDIATRIC NEUROLOGY; Ozdirim,E;
15(4):312-316 (1996)]. Microcephaly results from cell loss during
brain development due to various kinds of DNA damage. There may be premature
atherosclerosis, high lipofuscin accumulation in neurons and
[Alzheimer's](../lifeext/Alzheimer.html)
neurofibrillary tangles. The most common causes of death are pneumonia (probably
due to the general atrophy) and
neurodegeneration [[HUMAN MOLECULAR GENETICS; Navarro,CL; 15(2):R151-R161 (2006)](http://hmg.oxfordjournals.org/cgi/content/full/15/suppl_2/R151)].
Neurodegeneration may be indicative of the significance of failed TCR (or BER) in
postmitotic tissues leading to apoptosis, and the high rate of repair required
by brain tissue due to high oxidative metabolism [MECHANISMS OF AGEING AND
DEVELOPMENT; Stevnsner,T; 129(7-8):441-448 (2008)].
About 25% of cases have defective CSA protein and die at an average age of
12.5, whereas the rest have defective CSB protein and die at an average age of 6.5.
Oxidative stress lesions to DNA accumulate at a rapid rate in victims with CSB defects,
indicative of deficient Base Excision Repair
(BER) [[THE FASEB JOURNAL; Tuo,J; 17(6):668-674 (2003)](http://www.fasebj.org/cgi/content/full/17/6/668)
and [MOLECULAR AND CELLULAR BIOLOGY; de Waard,H;
24(18):7941-7948 (2004)](http://mcb.asm.org/cgi/content/full/24/18/7941)]. Despite showing many of the same symptoms as
XP victims, Cockayne syndrome victims have no predisposition
to cancer because of inhibited transcription binding leading to a
high rate of apoptosis (to which is attributed
features of premature aging). Cancer cells are heavily dependent upon
transcription, so it is reasonable that defective TCR would strongly inhibit
proliferation, but favor high levels of senescence or apoptosis ("accelerated
aging" rather than
cancer) [[THE AMERICAN JOURNAL OF HUMAN GENETICS; Licht,CL; 73(6):1217-1239 (2003)](http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=14639525)].
Transgenic mice that replicate Cockayne Syndrome show suppression of
GH/[IGF1−1](../nutrceut/GH_IGF1.html)PLoS BIOLOGY; van der Pluijm,I; 5(1):e2 (2007)].
**Trichothiodystrophy** (**TTD**) is due to defects in the
[transcription
factor](http://en.wikipedia.org/wiki/Transcription_factor) [**TFIIH**](http://en.wikipedia.org/wiki/Transcription_Factor_II_H) protein required for both NER and normal
[transcription](http://en.wikipedia.org/wiki/Transcription).
Most often these defects are in the XPB (3´−>5´
[helicase](http://en.wikipedia.org/wiki/Helicase)) or
XPD (5´−>3´ helicase) subunits of TFIIH. One type of mutation in XPD
leads to xeroderma pigmentosum, whereas other mutations lead to
TTD [[HUMAN MOLECULAR GENETICS; Botta,E; 11(23):2919-2928 (2002)](http://hmg.oxfordjournals.org/cgi/content/full/11/23/2919)].
TTD patients do not show increased incidence of cancer. Whereas XP patients
experience neuronal degeneration, Cockayne Syndrome (CS) and TTD patients suffer from
failure to develop brain myelin. CS and TTD patients may suffer more from defective
normal transcription, whereas XP patients may suffer more from defective
transcription in
NER [[NEUROSCIENCE; Kraemer,KH; 145(4):1388-1396 (2007)](http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17276014)]. TTD victims
(including transgenic mice) show more accelerated aging than victims of Werner, Cockayne or
Bloom Syndrome. The aging phenotype (which includes osteoporosis, early greying, cachexia
and neurological abnormalities) is attributed to increased apoptosis as well as
impaired cell functioning [SCIENCE; de Boer,J; 296:1276-1279 (2002)].
Like XP, [**Ataxia
Telangiectasia**](http://www.biocarta.com/pathfiles/atmPathway.asp) (**AT**) is a hereditary disease (defective Ataxia Telangiectasia
Mutated, **ATM**, gene) that
reduces DNA repair and greatly increases the risk of cancer. Unlike XP, AT affects DSB repair
rather than NER, and mainly increases leukemia or lymphoma cancer-types.
AT victims exhibit growth retardation, gonadal atrophy, graying hair, immune deficiency,
accelerated telomere loss, genetic instability and cerebellar degeneration, particularly
of Purkinje and granule neurons. Neurodegeneration is the most prominent feature of
AT [NEUROMOLECULAR MEDICINE; Frappart,P; 8(4):495-511 (2006)] as a result of the
vulnerability of Purkinje cells to oxidative
stress [[THE JOURNAL OF NEUROSCIENCE; Chen,P; 23(36):11453-11460 (2003)](http://www.jneurosci.org/cgi/content/full/23/36/11453)].
"Ataxia" means impaired motor coordination,
and ATM victims require a wheelchair before becoming teenagers due to loss of cells in cerebellum.
Clusters of dilated blood vessels (telangiectasia, "spider
veins") appear on the whites of eyes. ATM victims usually die in their teens [CELL;
Rass,U; 130(6):991-1004 (2007)]. Inhibition of ATM under conditions of DNA damage
reduces cell senescence and increases
apoptosis [[JOURNAL OF BIOLOGICAL CHEMISTRY; Zhang,X; 280(20):19635-19640 (2005)](http://www.jbc.org/cgi/content/full/280/20/19635)]
or simply reduces senescence[MOLECULAR BIOLOGY OF THE CELL; Moiseeva,O; 17(4):1583-1592 (2006)](http://www.molbiolcell.org/cgi/content/full/17/4/1583)].
Nonetheless, cells of AT patients are resistant to apoptosis and do not undergo cell cycle
arrest when subjected to ionizing radiation, possibly due to the anti-apoptotic action of
AP−1 [[JOURNAL OF BIOLOGICAL CHEMISTRY; Weizman,N; 278(9):6741-6747 (2003)](http://www.jbc.org/cgi/content/full/278/9/6741)].
Tissues containing rapidly-dividing cells (such as the cells in the epithelium) show most
of the signs of aging. But the normal slow loss of cerebellar Purkinje cells is greatly
accelerated, leading to ataxia. Ca2+/cAMP Response Element Binding protein **CREB**
has anti-apoptotic action related to transcription of Bcl−2 and neuron growth factors.
Dysregulation of ATM-mediated phosphorylation of CREB in response to DNA damage may be a
significant factor in the neurodegeneration associated with
AT [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Shi,Y;
101(6):5898-5903 (2004)](http://www.pnas.org/cgi/content/full/101/6/5898)]. Although the primary symptom of AT is degeneration of the
cerebellum, the ATM protein is activated by DNA double-strand breaks [SCIENCE; Abraham,
RT; 308(5721):510-511 (2005)]. ATM stimulation in AT patients is more sensitive to
ionizing radiation & alkylating
agents than to ultraviolet radiation, whereas the reverse is true in XP patients.
XP patients are defective in NER, whereas AT patients are defective in cell cycle
control [[JOURNAL OF RADIATION RESEARCH; Kan'o,M; 48(1):31-38 (2007)](http://www.jstage.jst.go.jp/article/jrr/48/1/48_31/_article)].
Additionally, absence of ATM protein increases telomerase instability &
loss of telomeres [ONCOGENE 21:611-618 (2002)] because DNA-damage response is part
of telomere protection and maintenance [NATURE; Verdun,RE; 447:924-931 (2007)].
Like XP, [Fanconi Anemia](http://en.wikipedia.org/wiki/Fanconi_anemia) (**FA**) is a hereditary disease associated with
chromosome instability and greatly increased risk of cancer. Increased apoptosis of
hematopoetic cells typically leads to pancytopenia by age 7, with the surviving
cells characterized by genetic instability leading to acute myeloid leukemia (AML,
the most common cause of cancer in FA patients) [CELL;Niedernhofer,L;
123(7):1191-1198 (2005) and NATURE REVIEWS; D'Andrea,AD; 3(1):23-34 (2003). Median
age of death is 16, most commonly due to bone marrow failure.
Premature aging features include progressive bone marrow failure,
premature reproductive aging, hyperinsulinaemia, hypothyroidism and growth hormone
deficiency [[NUCLEIC ACIDS RESEARCH; Grillari,J; 35(22):7566-7576 (2007)](http://nar.oxfordjournals.org/cgi/content/full/35/22/7566)]. Other
FA symptoms are only marginally associated with an accelerated aging phenotype: hearing
impairment, skeletal abnormalities, cardiac abnormalities, and cafe-au-lait skin spots.
All cellular elements in the blood (erythrocytes, leukocytes, and platelets) are depressed.
FA symptoms can result in disruption of proteins required for repair of
interstrand DNA cross-links, inclucing BRCA2.
Replication fork arrest during the S phase of the cell cycle due to
DNA cross-links can activate FA protein complexes to excise cross-links and thereby
create DSBs that can be repaired by homologous
recombination [[GENES & DEVELOPMENT; Kennedy,RD; 19(24):2925-2940 (2005)](http://genesdev.cshlp.org/content/19/24/2925)].
An increase in anemia prevalence is regarded as part of the normal aging
phenotype [JOURNAL OF THE AMERICAN GERIATRIC SOCIETY; Rothstein,G;
51(3 Suppl):522-526 (2003)],
and spontaneous DNA interstrand crosslink damage has been proposed to be the cause
of that anemia [[THE EMBO JOURNAL; Prasher,JM; 24(4):861-871 (2005)](http://www.nature.com/emboj/journal/v24/n4/full/7600542a.html)].
An analysis of human segmental progerias observed that the progerias with shortened
telomeres also showed grey hair, alopecia and nail atrophy — whereas those not having
shortened telomeres did not have those features. The study even hypothesized that
fingernail growth velosity may be a biomarker of aging [JOURNAL OF GERONTOLOGY;
Hofer,AC; 60(1):B10-B20 (2005)]. A similar study observed that although most segmental
progerias are associated with increased risk of cancer, Hutchinson-Gilford progeria and
Cockayne syndrome are not. The study concluded that lipid metabolism genes are more
influential on human lifespan than genome integrity genes [THE INTERNATIONAL JOURNAL
OF BIOCHEMISTRY & CELL BIOLOGY; 37(5):947-960 (2005)].
The Senescence Accelerated Mouse (SAM) is a rodent model of accelerated aging which
is apparently related to free-radical damage, judging by various indices of such damage
in the rodent. Moreover, administration of the spin-trapping agent PBN at maturity
to reduce free-radical damage dramatically increases life span — providing support
for the free radical theory of aging [ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
854:239-250 (1998)]. This is in contrast to other segmental progerias which more often
support a DNA-repair-deficiency theory of aging.
Mouse studies indicate that mutants for Ku80/Ku86 — proteins essential for NHEJ —
show an accelerated aging phenotype (kyphosis, alopecia, conjunctivitis, rectal prolapse,
osteopenia, skin atrophy, epiphysial closure, reduced lifespan), but a 13-fold reduction
of cancer incidence [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Vogel,H;
96(19):10770-10775 (1999)](http://www.pnas.org/content/96/19/10770) and [MOLECULAR AND CELLULAR BIOLOGY; Li,H; 27(23):8205-8214 (2007)](http://mcb.asm.org/cgi/content/full/27/23/8205)]. The control
mice showed osteoporosis, epiphysial closure as well as skin and follicular atrophy after
70 weeks or greater, whereas these symptoms were seen in the Ku 86 knockout mice
at 37 weeks, 22 weeks, and 37 weeks,
respectively [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Vogel,H;
96(19):10770-10775 (1999)](http://www.pnas.org/content/96/19/10770)]. The Ku 86 knockout mice exhibited earlier
onset of cancer, despite an overall reduced incidence (which may have been due to the
shortened lifespan and the increased cellular
senescence [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Vogel,H;
96(19):10770-10775 (1999)](http://www.pnas.org/content/96/19/10770)].
Mice with mutated XPD (a protein required for the TFIIH protein that causes
DNA unwinding in NER) show an accelerated aging phenotype which includes
osteoporosis, kyphosis, early graying, cachexia and reduced lifespan [SCIENCE;
de Boer,J; 296:1276-1279 (2002)]. Mice
mutant for reduced levels of **Brca1** (a protein for DSB repair) show both
increased cellular senescence and an accelerated aging phenotype (kyphosis, osteoporosis,
slow wound healing, reduced dermal thickness, muscular
atrophy) [[GENES & DEVELOPMENT; Cao,L; 17(2):201-213 (2003)](http://www.genesdev.org/cgi/content/full/17/2/201)]. Mice with deficient
p53-related p63 protein also show increased cellular senescence associated with tissue
histology reflecting an accelerated aging
phenotype [[GENES & DEVELOPMENT; Keyes,WM; 19(17):1986-1999 (2005)](http://www.genesdev.org/cgi/content/full/19/17/1986)]. Similarly,
mice deficient in ZMPSTE24 protease show hyperactivation of tumor suppressor protein p53,
leading to increased cell senescence without increased apoptosis — and an acclerated
aging phenotype [NATURE; Varela,I; 427:564-568 (2005)].
The linkage of accelerated aging to nuclear DNA repair defects implies both a direct
linkage to cancer as well as cell dysfunction due to increased DNA damage/mutation,
or an indirect linkage due to increased cellular senescene and apoptosis —
depending on what causes the "aging phenotype". Transgenic
mice with hyperactive p53 protein show decreased cancer along with increased apoptosis
and cellular senescence associated with an aged phenotype and shortened
lifespan [NATURE; Tyner,SD; 415:45-53 (2002),
[GENES & DEVELOPMENT; Maier, B; 18(3):306-319 2004)](http://genesdev.cshlp.org/content/18/3/306),
and [BLOOD; Dumble,M; 109(4):1736-1742 (2007)](http://bloodjournal.hematologylibrary.org/cgi/content/full/109/4/1736)].
Markers of aging for the first of these studies included
hair sparseness (hair growth decreases linearly with age in mice), slowing of wound
healing, reduced dermal thickness & subcutaneous adipose (both of which normally
decline with age), lordokyphosis (hunchbacked spine), muscle atrophy, and reduced
vigor [NATURE; Tyner,SD; 415:45-53 (2002)]. Conversely, transgenic mice with
mutated p66shc gene show impaired p53, reduced apoptosis in response
to stress and "decelerated aging" (lifespan extended
30% [NATURE; Migliaccio,E; 402:309-313 (1999)]. Transgenic mice with
extra p53 genes had normal basal p53 activity, normal lifespans (no signs of
accelerated aging), and enhanced resistance to DNA damage and cancer —
probably because of enhanced protection against p53
mutation [[THE EMBO JOURNAL; Garcia,CI; 21(22):6225-6235 (2002)](http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=12426394)]. Mice that
were transgenic with extra genes of both p53 and **Arf** (with normal activity
of both) had strong cancer resistance, increased levels of reduced glutathione (GSH)
antioxidant, and lifespan increase of 16% [NATURE; Matheu,A; 448:375-380 (2007)].
In the liver (but not the brain), old rats show less than half the
apoptosis of young rats in response to DNA damage [NATURE MEDICINE; Suh,Y;
8(1):3-4 (2002)], indicative of an increased vulnerability to cancer. Cellular
senescence isn't simply a result of shortened telomeres, it is often
the result of unrepaired nuclear DNA damage throughout chromosomes [NATURE
CELL BIOLOGY; Sedelnikova,OA; 6(2):168-170 (2004) and MECHANISMS OF AGEING AND
DEVEOPMENT; von Zglinicki,T; 126(1):111-117 (2005)], although telomere-initiated
senescence is probably also a DNA damage response [NATURE; d'Adda di
Fagagna,F; 426:194-198 (2003)]. Although estimates of the number of senescent
cells vary from between less than 1% to over 15%, such cells are prominent
in osteoarthritis and atherosclerosis — and, where not prominent, contribute
to cellular dysfunction and carcinogenesis of adjacent cells by secretion of
cytokines, growth factors and other damaging
agents [NATURE REVIEWS; Campisis,J; 8(9):729-740 (2007)
and [JOURNAL OF BIOLOGICAL CHEMISTRY; Coppe,J;
281(40):29568-29574 (2006)](http://www.jbc.org/cgi/content/full/281/40/29568)]. Foci of DNA damage as markers of
senescent cells provide the highest estimates (15%) of cellular
senescence in aged animals [SCIENCE; Herbig,U; 311:1257 (2006)].
Accelerated aging diseases can be useful models for learning about the mechanisms of aging if
they truly represent accelerated aging. When the question of the essence of aging remains undetermined,
validating biomarkers or a model of accelerated aging leads to circular reasoning. Some question that there are
***any*** disease conditions which can be called "accelerated
aging" [AGING CELL; Miller,RA; 3(2):47-51 (2004)]. If it is possible to slow aging, it should
be possible to accelerate aging, but ***proving*** that aging has been slowed is much easier
than proving that aging has been accelerated because a long-lived organism is sufficient proof of decelerated
aging but
a short-lived organism could be the result of a specific defect. Or else the mechanisms of "accelerated
aging" could be different from those of "normal aging". But lifespan studies of nematodes
show progressive lamin disorganization in normal aging comparable to that in the accelerated
aging of HGPS progeria, and the rate of these changes can be manipulated by insulin/IGF−1-like
signaling [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Haithcock,E; 102(46):16690-16695
(2005)](http://www.pnas.org/cgi/content/full/102/46/16690)]. Similar defects in nuclear structure & function between HGPS cells and cells
in elderly humans also supports the contention
that HGPS is accelerated aging [SCIENCE; Scaffidi,P; 312:1059-1063 (2006)].
Dermatologists commonly distinguish **photoaging** from **chronological aging** in the skin,
attributing most skin aging to the former rather than the latter. Singlet oxygen from ultraviolet
light increases mitochondrial DNA
deletion [[JOURNAL OF BIOLOGICAL CHEMISTRY; Berneburg,M; 274(22):15345-15349 (1999)](http://www.jbc.org/cgi/content/full/274/22/15345)].
Ultraviolet radiation stimulates collagen degradation while inhibiting collagen
production [[AMERICAN JOURNAL OF PATHOLOGY; Quan,T; 165(3):741-751 (2004)](http://ajp.amjpathol.org/cgi/content/full/165/3/741)], increases oxidative
DNA damage [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Kozman,S;
102(38):13538-13543 (2005)](http://www.pnas.org/cgi/content/full/102/38/13538)] and causes stress-induced premature senescence in skin
fibroblasts [[JOURNAL OF CELL SCIENCE; Debacq-Chainiaux,F; 118(Pt 4):743-758 (2005)](http://jcs.biologists.org/cgi/content/full/118/4/743)]. If
aging is damage to macromolecules, cells and tissues then it should not be surprising that
exogenous sources of damage could cause "accelerated aging" of specific tissues —
a "tissue-specific segmental progeria". The fact that nuclear DNA damage from exogenous agents
results in a phenotype that greatly resembles normal aging lends credence to the idea that such
damage is the basis of normal aging.
Mice have been regarded as examples of "accelerated
aging" [AGING CELL; Miller,RA; 3(2):47-51 (2004)], but mice could also be
given as examples of segmental human progeria because of their high susceptibility
to cancer and their absence of atherosclerosis and Alzheimer's Disease. All human
aging could be called segmental in the sense that some people get cancer, atherosclerosis
and Alzheimer's Disease, whereas others do not. If there are multiple
forms of aging damage then there cannot be a single aging biomarker or aging phenotype.
If reduced longevity alone were a sufficient criterion for accelerated aging, then any genetic
defect which increases mortality — or even a dangerous occupation — would qualify.
[(return to contents)](#contents)
### XV. LONGEVITY GENES (FLIES & WORMS)
The nematode worm [*Caenorhabditis elegans*](http://en.wikipedia.org/wiki/Caenorhabditis_elegans) (***C. elegans***,
which is the size of a comma, and lives a few weeks) and the fruit fly
[*Drosophila melanogaster*](http://en.wikipedia.org/wiki/Drosophila_melanogaster) (***Drosophila***,
which lives a few months) are the most common invertebrate model species used
in biology. Upon reaching maturity both species are composed post-mitotic
cells, except for the germline.
A study of the entire genome of ***Drosophila*** during
the aging process has led to the conclusion that 300 to 350 genes control
aging [CURRENT BIOLOGY; Pletcher,SD; 12(9):712-723 (2002) and CURRENT BIOLOGY;
Rose, MR; 12(9):R311-R312 (2002)]. (By extrapolation, about 500 genes would
control aging in humans.) Determining what those genes do would be a major step
toward understanding the causes of aging.
***Drosophila*** have the natural antioxidant enzymes SuperOxide Dismutase
(**SOD**) & CATalase (**CAT**), but
no glutathione peroxidase. ***Drosophila*** were created with
(1) extra Cu/Zn−SOD (cytoplasmic SOD) genes (2) extra CAT genes
and (3) extra Cu/Zn−SOD ***and*** extra CAT genes. Only the
flies in the third category, having both extra genes showed extended
lifespan. These transgenic flies showed 26% greater SOD activity, 73%
greater CAT activity and 34% longer
lifespan [[JOURNAL OF BIOLOGICAL CHEMISTRY 270(26):15671-15674 (1995)](http://www.jbc.org/cgi/content/full/270/26/15671)].
The authors later stated that the experiments were not conclusive because of
the genetic background of the organisms and because of artifacts of the transgenic
methods [EXPERIMENTAL GERONTOLOGY; Orr,WC; 38:227-230 (2003)]. Nonetheless,
transgenic mice expressing mitochondrial catalase by 50 times that seen in normal
mice increased maximum lifespan by about 20% [SCIENCE; Schriner,SE;
308:1909-1911 (2005)].
In 1988 geneticist Tom Johnson of the University of Colorado announced the
discovery of a mutant gene in ***C. elegans*** that at 25ºC increased
mean life span 65% and maximum lifespan 110% [GENETICS 118:75-86
(1988)]. Johnson named the gene **age−1** in the expectation that other genes
for aging would be found. [Caloric Restriction with Adequate Nutrition](../calories/calories.html) (CRAN)
further extends the lifespan of age−1 mutants. age−1 mutants
were shown to have elevated Cu/Zn SOD and CAT (nematodes,
unlike vertebrates, do not have glutathione peroxidase) [BIOCHEMICAL
JOURNAL 292:605-608 (1993)]. age−1 mutants show a lower rate of
deletions in the mitochondrial genome than wild-types [NUCLEIC ACID
RESEARCH 23(8):1419-1425 (1995)]. ***C. elegans*** homozygous
for nonsense **age−1** gene mutations have shown a ten-fold increase
in maximum lifespan [[AGING CELL; Ayyadevara,S; 7(1):13-22 (2008)](http://www.ncbi.nlm.nih.gov/pubmed/17996009)].
Nematodes normally live under the soil where oxygen concentrations are 1%
to 2%, suggesting that the higher levels of antioxidant enzymes may only be
of advantage as an adaptation to the atmospheric oxygen (21% oxygen) of
laboratory conditions. When age−1 mutants are raised under more natural conditions
of low food-availability they die more quickly than wild-type [NATURE
405:296-297 (2000)].
***C. elegans*** **age−1** was later
identified [[GENETICS; Malone,EA; 143(3):1193-1205 (1996)](http://www.genetics.org/content/143/3/1193.long)].
as **daf−23**,
part of the gene family including the **daf−2**
(**DA**uer **F**ormation gene) mutation of which causes the nematode to go
into the developmentally arrested **dauer** state (from the German
***dauern***, meaning "to endure"). The daf−2 DNA gene sequence
most resembles the mammalian gene for the
**[IGF1−1](../nutrceut/GH_IGF1.html)** (**Insulin-like Growth
Factor−1**) receptor, but is also quite similar to the **insulin** receptor.
(In ***C. elegans*** the single daf−2 receptor corresponds in function
to the two mammalian receptors — insulin and IGF−1.) The **age−1** gene product
is a signaling kinase which acts downstream of the **daf−2** receptor.
The dauer state is
naturally seen among ***C. elegans*** larvae under conditions
of low food availability. The dauer is non-feeding, non-reproductive and
resistant to damage from ionizing radiation, extreme temperature &
free-radicals ("stress-resistant"). If conditions improve, the
dauer moults to a normal adult state. Autophagy genes are essential for dauer
formation and are essential for the lifespan increase associated with
dauer [SCIENCE; Melendez,A; 301:1387-1391 (2003)].
Dauer larvae do not feed and the time
spent in a quiescent state of reduced metabolism ("suspended animation")
may not count as life extension. Some ticks stop metabolizing if they cannot eat, and
can survive in a quiescent state for years. ***Drosophila*** cooled from
25ºC to 15ºC live more than 3 times
longer [[JOURNAL OF BIOLOGICAL CHEMISTRY; 32(1):103-121 (1917)](http://www.jbc.org/cgi/reprint/32/1/103)] — a
temperature reduction which should be associated with a halving of metabolic rate.
Among other effects, Daf proteins
reduce fertility & movement of ***C. elegans*** while shifting metabolism toward the breakdown
of fat — analogous to the metabolic shift seen in humans when insulin levels
fall off. But the lifespan increases of the dauer state are not entirely due to
reduced metabolism — increased antioxidant enzyme levels and more stress-resistance
proteins play a role. Strong reduction of function mutations to **daf−2** or
**age−1** (the "insulin/IGF−1 pathway") cause the dauer state, whereas
weak mutations simply cause a more quiescent phenotype having dauer-like qualities of
increased antioxidant enzymes, extended lifespan and lower metabolic
rate [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); van Voorhies,WA;
96(20):11399-11403 (1999)](http://www.pnas.org/cgi/content/full/96/20/11399)]. In particular, **daf−2** mutations increase Mn−SOD
expression in the mitochondria [[THE FASEB JOURNAL; Honda,Y; 13(11):1385-1393 (1999)](http://www.fasebj.org/cgi/content/full/13/11/1385)].
Not only are daf−2
mutations associated with increased catalase, but ***C. elegans*** with defective
peroxisomal catalase genes have been proposed as models of "accelerated
aging" [[JOURNAL OF BIOLOGICAL CHEMISTRY; Petriv,OI; 279(19):19996-20001 (2004)](http://www.jbc.org/cgi/content/full/279/19/19996)].
Some daf−2 mutants display the same phenotype, but
without reduced fertility [[GENETICS; Gems,D; 150(1):129-155 (1998)](http://www.genetics.org/cgi/content/full/150/1/129)]. Removal of gonads from
**daf−2** reduction-of-function nematodes increased lifespan even more than the
reduction of **daf−2** function [SCIENCE; Arantes-Oliveira,N; 302:611 (2003)].
***C. elegans*** on CRAN get further life extension with **daf−2**
mutations, indicating that CRAN and insulin/IGF−1 defects extend lifespan by different
mechanisms [EXPERIMENTAL GERONTOLOGY; Houthoofd,K; 38(9):947-954 (2003)
and [PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Lakowski,B;
95(22):13091-13096 (1998)](http://www.pnas.org/cgi/content/full/95/22/13091)].
Reduced expression of daf−2 or age−1 cannot induce the dauer state or extend lifespan
without the **Daf−16** transcription factor, which is downstream from the other two
proteins. The signalling dependency is:
**daf−2 -> age−1 -> PKB -> Daf−16**
where PKB is **P**rotein **K**inase **B**. Note that the dependency
relationship is such that high "insulin signalling" (high daf−2/age−1 expression)
leads to low Daf−16 activity, whereas defective mutations of daf−2/age−1 (or starvation)
leads to high Daf−16 transcription activity, which causes the dauer-like lifespan extension.
A table summarizes the homologous proteins between ***C. elegans*** and
mammals:
**Homologous Proteins (Gene products)**
| ***C. elegans*** | **daf−2** | **age−1** | **PKB** | **Daf−16** | | **Daf−18** |
| **mammals** | **Ins/IGF−1** | **PI3K** | **Akt** | **FOXO** | | **PTEN** |
**PI3K blocks Daf−16 longevity**| PI3K blocks Daf−16 longevity |
Mammalian homologs to the ***C. elegans*** genes/proteins
are the subject of intense interest concerning possible regulation of mammalian
lifespan. As has been mentioned, the ***C. elegans*** **daf−2** receptor
acts like a mammalian insulin/IGF−1 receptor. ***C. elegans*** **age−1**
corresponds in mammals to the inositol lipid kinase
**PI3K** (**P**hosphatidyl**I**nositol **3**−**K**inase). Mammalian protein
kinase B (**PKB**) is also called **Akt** (a kinase activated by phosphorylation of
serine and/or threonine residues). **Daf−16** corresponds to the mammalian family of
transcription factors called **FOXO** (**F**orkhead b**OX** class **O**),
which regulates stress response. When FOXO proteins are
phosphorylated by protein kinase B they are excluded from the nucleus and degraded
upon ubiquitination. **Daf−16/FOXO** gene transcription can lead to DNA-repair stimulation,
([cell cycle](../health/cancer.html#cellcycle) arrest,
apoptosis, and induction of heat shock proteins & anti-oxidant enzymes [SCIENCE;
Brunet,A; 303:2011-2015 (2004)]. Variations in FOXO genetics has a significant effect
on human lifespan [[EUROPEAN JOURNAL OF HUMAN GENETICS; Kuningas,M; 15(3):294-301 (2007)](http://www.nature.com/ejhg/journal/v15/n3/full/5201766a.html)].
Stress signals from JNK MAPKs exert their effects through
**Daf−16/FOXO** in parallel with insulin/IGF−1
signalling [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Oh,S; 102(12):4494-4499 (2005)](http://www.pnas.org/cgi/content/full/102/12/4494)].
In sum, when the **daf−2/insulin/IGF−1 pathway** is intact, **age−1/PI3K**
phosphorylation of **Daf−16/FOXO** prevents that protein from entering the nucleus
to activate defensive/hibernation "longevity genes".
The mammalian PI3K/Akt pathway activates cell growth & proliferation while at the same time
promoting cell survival by inhibiting macroautophagy and
apoptosis [[JOURNAL OF BIOLOGICAL CHEMISTRY; Arico,S; 276(38):35243-35246 (2001)](http://www.jbc.org/cgi/content/full/276/38/35243)].
**PTEN** normally dampens the PI3K/Akt pathway, thereby acting as a tumor-suppressor.
By inactivation of the tumor suppressor protein **PTEN**, oxidative stress
activates PI3K — resulting in PKB/Akt promotion of
proliferation [[THE EMBO JOURNAL; Leslie,NR; 22(20):5501-5510 (2003)](http://www.nature.com/emboj/journal/v22/n20/full/7590924a.html)]. PI3K activation
increases expression of ARE ([Antioxidant-Responsiveness Element)](../nutrceut/AntiOxidants.html#enzymes) genes leading to the synthesis of more
[antioxidant enzymes](../nutrceut/AntiOxidants.html#enzymes).
**PTEN** mutations that inactivate **PTEN** expression allow unrestrained activity
of PI3K/Akt, which often leads to
cancer [[MEDICAL SCIENCE MONITOR; Chu,EC; 10(10):RA235-RA241 (2004)](http://www.medscimonit.com/pub/vol_10/no_10/6275.pdf)]. The mammalian
**PTEN** gene corresponds to the ***C. elegans*** **daf−18** gene.
Mutations in **daf−18**
can suppress the dauer phenotype and longevity induced by **daf−2** or **age−1**
inactivation [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Mihaylova,VT;
96(13):7427-7432 (1999)](http://www.pnas.org/cgi/content/full/96/13/7427)].
(Human atherosclerotic plaques contain a high proportion of senescent cells, probably because
of increased p53-induced senescence as a result of **Akt** phosphorylation by insulin
— underlying the relationiship between diabetes and atherosclerosis. These senescent cells
produce high levels of proinflammatory molecules that promote atherogenesis. Inhibition of
**FOXO3** by **Akt** is an essential factor in the senescent growth
arrest [[THE EMBO JOURNAL; Miyauchi,H; 23(1):212-220 (2004)](http://embojournal.npgjournals.com/cgi/content/abstract/23/1/212)].)
The mammalian PI3K/Akt pathway can be inhibited by rapamycin, which inhibits the kinase **mTOR/TOR**
— [(mammalian)
Target Of Rapamycin](http://en.wikipedia.org/wiki/Mammalian_target_of_rapamycin). Inhibition of mTOR by rapamycin or calorie restriction triggers
macrophagy. ***Drosophila*** fed rapamycin have shown extended
lifespan [[CELL METABOLISM; Bjedov,Z; 11(1):35-46 (2010)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824086/)] and rapamycin has
the same effect on mice [[NATURE; Harrison,DE; 460:392-396 (2009)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786175/
TARGET=)]. Changes in the expression of
genes controlled by Tor, Ras, and Sch9 in yeast causes a switch to glycerol calorie
source — extending
lifespan [[PLOS GENETICS; Wei,M; 5(5):e1000467 (2009)](http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1000467)]. (For more information
on the PI3K/Akt pathway see [Signalling Molecules and Transcription Factors](../health/cancer.html#signalling).)
In ***Drosophila*** a defective **chico** "insulin/IGF−1 signalling
gene" has been shown to increase lifespan 48%, reduce fertility and increase
antioxidant enzymes and produce a fly that is half the size of wild-type
flies [SCIENCE; Clancy,DJ; 292:104-106 (2001)]. **Chico** mutants have fewer cells
and smaller cells [CELL; Bohni,R; 97(7):865-875 (1999)]. As with
***C. elegans***, the single insulin/IGF−1 receptor in
***Drosophila*** is believed to correspond with the distinct (but similar)
insulin and IGF−1 receptors in humans. **Chico** protein corresponds to the mammalian
Insulin Receptor Substrate (**IRS**) "docking protein" that is
associated with the IGF−1 receptor, so defective mutations result in a similar effect as
defective **daf−2/age−1/Insulin/IGF−1** signalling.
The ***C. elegans*** gene **clk−1** (the
"clock" gene), alters growth rate, cell cycle time and other
"timed" events in the nematode life-cycle. Defective
clk−1 genes reduce metabolism and extend lifespan, whereas
overexpression of clk−1 reduces lifespan. The sluggish clk−1
mutants are defective in [Coenzyme Q](../nutrceut/CoEnzymeQ.html) synthesis (essential
for mitochondrial energy generation) and when they are fed bacteria that do not
supply CoEnzyme−Q their development
arrests [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA) 98(2):421-426
(2001)](http://www.pnas.org/cgi/content/full/98/2/421)], and they revert to anaerobic metabolism that
produces less energy while avoiding much of the free radical generation associated
with oxidative phosphorylation [SCIENCE; Larsen, PL; 295:120-123 (2002)].
***C. elegans*** lifespan extension has been achieved by
mitochondrial function inhibition [SCIENCE;Dillin,A; 298:2398-2401 (2002)].
***C.elegans*** given anti-oxidant compounds that mimic the action of both
superoxide dismutase and catalase show significant increases
in mean and maximum lifespan [SCIENCE; Melov,S; 289:1567-1569 (2000)]. Nematode
daf−2/age−1 impairment only increases lifespan when the defect occurs in neurons, not
muscle or intestine — possibly because neurons are more vulnerable to
free-radicals [SCIENCE; Wilkow,CA; 290:147-150 (2000)]. The **HSF−1**
transcription factor (Heat Shock Factor, which regulates heat shock response) has been
shown to be essential for Daf−16 induced longevity in ***C.elegans***.
Reduced activity of **HSF−1** reduces lifespan and additional **HSF−1**
gene copies have increased lifespan by 40%. Small heat shock proteins which can
inhibit toxic protein aggregation seem to be the key to this effect [SCIENCE; Hsu,A;
300:1142-1145 (2003)].
Similarly, ***Drosophila*** bred for longevity have displayed increased
levels of small heat shock proteins [JOURNALS OF GERONTOLOGY; Kurapati,R;
55A(11):B552-B559 (2000)]. Overexpression of small heat shock proteins in
***Drosophila*** has been shown to extend their lifespan by
30% [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Wang,H; 101(34): 12610-12615(2004)](http://www.pnas.org/cgi/content/full/101/34/12610)].
A number of mutations can produce the effects of CRAN by indirect means. For example, the
**eat** mutations in ***C. elegans*** result in reduced efficiency of
the pharynx to pump food [[GENETICS; McKay,JP; 166(1):161-169 (2004)](http://www.genetics.org/cgi/content/full/166/1/161)]. More subtly, the **Indy**
(I'm Not Dead Yet) mutation in ***Drosophila*** results in defective membrane
transport of Krebs cycle intermediates [SCIENCE; Rogina,B; 290:2137-2140 (2000)].
Metabolic rate is not reduced in ***C. elegans*** **daf−2** mutants
having extended lifespan, but efficiency of oxidative phosphorylation is increased [AGING
CELL; Braeckman,BP; 1(2):82-88 (2002)]. Nor is metabolic rate reduced in ***Drosophila***,
either in CRAN or defective insulin/IGF−1 signalling (**chico** mutants) having extended
lifespan [EXPERIMENTAL GERONTOLOGY; Hulbert,AJ; 39(8):1137-1143 (2004)]. Cohorts of
***Drosophila*** with no obvious genetic defects can have up to a five-fold difference
in lifespan with no significant difference in metabolic rate [EXPERIMENTAL GERONTOLOGY;
Hulbert,AJ; 39(8):1137-1143 (2004) and [JOURNAL OF APPLIED PHYSIOLOGY; van Voorhies,WA; 95(6):2605-2613 (2003)](http://jap.physiology.org/cgi/content/full/95/6/2605)].
[(return to contents)](#contents)
### XVI. LONGEVITY GENES (MAMMALS)
Mice (and other mammals) have distinct insulin and
[IGF1−1](../nutrceut/GH_IGF1.html) receptors, unlike flies and
worms, that have a single insulin/IGF−1-like receptor. But defects of either of these
receptors have been shown to result in a lifespan increase for mice. Insulin resistance is
associated with diabetes and is even recommended as a biomarker of aging — so it is
mysterious why blocked insulin signaling can extend lifespan. Fat-specific Insulin Receptor
Knock-Out (**FIRKO**) mice have reduced fat mass, normal calorie intake and an increased
maximum lifespan of 18% [SCIENCE; Bluher,M; 299:572-574 (2003)]. Yet deletion of
all insulin receptor genes in mice results in neonatal death [EMBO JOURNAL; Joshi,RL;
15(7):1542-1547 (1996)].
Two single gene mutations on mice — one on chromosome 11 (**Prop−1** locus,
**Ames dwarf**) and the other on chromosome 16 (**Pit−1** locus,
**Snell dwarf**) — extend
mean & maximum lifespan significantly. Snell dwarfs have a defective pituitary transcription
factor which is downstream from the protein which is defective in Ames dwarfs. Both mutations
preclude normal development of the anterior pituitary. In both cases the adults are one-third
the size of normals and in both cases there are defects in production of **Growth
Hormone** (**GH**), prolactin and **Thyroid-Stimulating
Hormone** (**TSH**). Comparable to nematode daf−2/age−1 mutants, dwarf mice
have impaired IGF−1/insulin sensing pathways.
Insulin-like Growth Factor−1 (IGF−1) is a mitogen and an important
mediator of the GH effect. The dwarf mice have greatly diminished IGF−1 blood
levels. Dwarf mice have higher antioxidant enzyme activity, lower body temperature and
reduced metabolism [JOURNALS OF GERONTOLOGY 56A(8):B340-B349 (2001)] as well as delayed
collagen cross-linking and delayed immune (T−cell)
aging [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Flurkey,K;
98(12):6736-6741 (2001)](http://www.pnas.org/cgi/content/full/98/12/6736)]. Fibroblasts from
Snell Dwarf mice have great resistance to injury by heat, hydrogen peroxide, cadmium,
UV light and paraquat [FASEB JOURNAL 17:1565-1566 (2003)] — a similar
stress-resistant pattern as is seen in **daf−2**/**age−1** mutants. Kidney disease
is common in rodents, but this is not the case for dwarfs.
The slope of the survival curves of dwarf mice match those of controls, indicating that
the rate of aging is not changed — rather the curve has been shifted to the right,
possibly due to slower development time to maturity. Ames dwarfs develop tumors at the same
frequency as wild-types, but at a later age [JOURNAL OF THE AMERICAN AGING ASSOCIATION;
Mattison,JA; 23:9-16 (2000)]. CRAN, by contrast, reduces the slope of
the survival curve. The fact that the lifespan of Ames Dwarf mice can be further extended by
CRAN [NATURE; Barke,A; 414:412 (2001)] shows that the mechanism of lifespan extension
in dwarfism is at least partially distinct from that of CRAN. Ames Dwarf mice show a
significantly delayed occurrence of [cancer](../health/cancer.html)
compared to normal mice [JOURNALS OF GERONTOLOGY; Ikeno,Y; 58A(4):B291-B296 (2003)] —
probably because IGF−1 promotes apoptosis in unanchored cells (notably, cancer cells) and
is anti-apoptotic in other cells.
"Knockout mice" (ie, mice with genes "knocked out") lacking GH show
significantly reduced IGF−1 and thyroid hormone. The knockout mice are one-third normal
weight and show a 60% lifespan extension (comparable to those of dwarf
mice) [[ENDOCRINOLOGY; Coschigano,KT; 141(7):2608-2613 (2000)](http://endo.endojournals.org/cgi/content/full/141/7/2608)]. As with Ames dwarfs,
insulin sensitivity is greater and plasma glucose & insulin may be reduced, resulting in
less [glycation](#protein) [JOURNALS OF GERONTOLOGY;
56A(8):B340-B349 (2001)]. Although knockout mice for IGF−1 are not viable, mice with half
their IGF−1 genes knocked-out (heterozygous knockouts) live 26% longer and show
resistance to oxidative stress without dwarfism, altered fertility or altered
metabolism [NATURE; Holzenberger,M; 42:182-187 (2003)].
Mice with defective **p66shc** gene resist apoptosis caused by paraquat,
hydrogen peroxide and UV light. The mice show a 30% increase in lifespan (less than
the lifespan increase in dwarf mice [NATURE; Migliaccio,E; 402:309-313 (1999)]. The
**p66shc** signal transduction pathway is activated by oxidative stress and
leads to apoptosis. Apoptosis due to oxidative stress is mediated by p53, and antagonized by
p21 (presumably sometimes by a p53-independent pathway in which **p66shc**
participates). The **p66shc** protein increases cellular oxidative stress as
a defense against infectious agents (lab mice are protected from pathogens). The
**p66shc** mutant mice do not survive well in cold (lab mice are kept warm).
The **p66shc** protein is downstream from the
IGF−1 receptor and is underphosphorylated in dwarf mice [HORMONE RESEARCH; Hozenberger,M;
62(Suppl 1):89-92 (2004)]. The protein is an activator of the **Ras** mitogen receptor.
Overexpression of the **klotho** gene extends the maximum lifespan of male mice about 20%,
but has little effect on females. Males have reduced insulin sensitivity, but females do not. Despite
resistance to both insulin & IGF−1, the mice have normal size & food intake, but
fertility is reduced [SCIENCE; Kurosu,H; 309:1829-1833 (2005)].
Reduced body size within a species often correlates with longer lifespan and reduced plasma IGF−1.
Great Danes (400 ng/mL plasma IGF−1) live about 7 years, whereas
Chihuahuas (40 ng/mL plasma IGF−1) can live over 15 years. Does low IGF−1
causing small body size lead to greater longevity — or is the smaller body size due to
reduced IGF−1 irrelevant to life-extension resulting from IGF−1 signalling? Ironically,
GH (and therefore, IGF−1) hormone replacement is touted as an anti-aging, rejuvenating
remedy for older humans — including such claimed benefits as improved cognition &
improved immune function (benefits attributed to ***reduced*** IGF−1 in mice).
It may be that high GH/IGF−1 is an example of "antagonistic pleiotrophy".
Larger animals with greater fertility and short lifespans are likely to be dominant in
an environment where successful competition with other animals is the key to survival. In
environments with scarce resources, but little competition, smaller size with reduced
fertility & greater longevity may result in more surviving offspring.
High GH and IGF−1 increases tissue development, metabolism and glucose utilization
at the cost of higher oxidative stress, more protein glycation and higher proliferation.
It may well be most conducive for survival to have high GH/IGF−1 during development, but
reduced GH/IGF−1 levels after maturation. From this point of view, GH replacement in
adults may not be a good idea.
Within mammalian species, small size is associated with greater longevity when the small
size is not due to inadequate nutrition. If DNA repair capability increases for larger species,
but is the same for larger members of the same species (who have more cells), then the larger
animals may be more vulnerable to tissue degeneration and cancer than the smaller members of
the same species. Dwarf mice and smaller breeds of dogs have less
Insulin-like Growth Factor−1 (IGF−1) and are less vulnerable to cancer [JOURNALS
OF GERONTOLOGY 51A(6):B403-B408 (1996)]. But if CRAN and IGF−1 reduction are a famine-like
trigger of the same defensive metabolism in the organism — more heat shock protein, more
antioxidant enzymes, greater DNA repair and reduced fertility (it would be wasteful to use
resources on producing offspring who have little chance of surviving) — then additive
effects of both would not be expected.
To say that IGF−1 and cell-signalling regulate aging is a half-truth — with the
missing half required to explain the mechanisms of aging. What lies at the end of the
cell signalling? The answer must be more antioxidant enzymes, more heat shock proteins
and/or better DNA repair — and/or fewer harmful agents like cortisol and inflammatory
cytokines. Aging is ultimately accumulated damage on the macromolecular,
cellular and tissue level — ultimately the result of a limited number of possible defenses
and a limited number of possible damaging agents. "Longevity genes" must result in
decreased aging-damage or increased aging-damage repair. Although means may be found to enhance
defenses to slow aging, the ultimate challenge is to find means to **repair** the damage.
(See [Growth Hormone (GH/IGF−1) Replacement](../nutrceut/GH_IGF1.html)
for more about GH and IGF−1.)
[(return to contents)](#contents)
### XVII. SIRTUINS AND DEACETYLASES IN AGING
**Sir2 deacetylates protein
with NAD+ as a co-factor**| Sir2 deacetylates protein with NAD<sup>+</sup> as a co-factor |
(For background on gene silencing by histone deacetylation, see
[Epigenetic Dysregulation](../health/cancer.html#epigenetic).)
Like ***Drosophila*** and ***C. elegans***, the budding yeast
***Saccharomyces cerevisiae*** (Brewer's yeast) has served as a model organism for aging research.
Of interest has been the ***S. cerevisiae*** **S**ilent **I**nformation
**R**egulator (**SIR2**) gene which produces the **Sir2** histone deacetylase
protein. Acylation of histones reduces their binding to DNA, thereby facilitating transcription,
whereas deacylation allows histones to bind to DNA thereby silencing gene expression.
**Replicative lifespan** in yeast refers to the lifespan of a "mother" cell
that buds-off "daughter" cells. The number of daughter cells that a mother
produces before it "dies of old age" is called the replicative lifespan. The
major cause of replicative aging is the "toxic" extra-chromasomal rDNA circles
which segregate and accumulate in the mother cell. Yeast with SIR2 deletions have a short lifespan,
whereas yeast with extra SIR2 genes have greatly extended lifespan [CELL; Longo,VD;
126(2):257-268 (2006)]. Gene silencing by deacetylation causes the
chromatin to become more closed & inaccessible, thereby reducing
genome instability [[GENES & DEVELOPMENT; Guarente,L; 14(9):1021-1026 (2000)](http://www.genesdev.org/cgi/reprint/14/9/1021)].
Yeast cells cease to divide under conditions of nutrient deprivation (severe calorie
restriction). The survival of yeast under such conditions has been called
**chronological lifespan** — and is regarded as a model for mammalian post-mitotic
cells, in contrast to replicative lifespan, which is regarded as a model for mammalian
proliferative cells. Deletion of SIR2 in yeast increases stress resistance and
increases chronological lifespan when calories are
restricted [[PLoS GENETICS; Kaeberlein,M; 3(5):e84 (2007)](http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17530929)].
SIR2 expression is activated by CRAN
([Caloric Restriction with
Adequate Nutrition](../calories/calories.html)), but neither CRAN nor extra SIR2 can silence genes without **NAD+**
(oxidized form of **N**icotinamide **A**denine **D**inucleotide) as a
co-factor [SCIENCE 289:2126-2128 (2000)]. The presence of a high NAD/NADH ratio in a
cell is an index of low energy production. CRAN yeast
with less NAD do not show greater longevity than ad-libitum fed yeast. The **PNC1** gene
encodes an enzyme which deaminates nicotinamide, and may be the upstream transducer of a
variety of low-intensity, longevity-activating stressors, including heat, osmosis and CRAN
— suggesting that life extension due to SIR2 is a generalized stress response [NATURE;
Anderson,RM; 423:181-185 (2003)].
Insofar as genetic instability (ribosomal DNA recombination, in particular) seems to be
the primary (fastest) "aging" mechanism in yeast, it is not surprising that gene
silencing extends yeast lifespan. But ribosomal DNA is far more stable in higher organisms.
In ***C. elegans*** **sir−2.1** — the gene most similar in DNA sequence
to yeast SIR2 — inactivates the receptor for the nematode version of insulin — thereby
activating Daf−16 protein production. Again, NAD+ is a necessary co-factor.
Doubling the **sir−2.1** gene in ***C. elegans*** apparently resulted in a 50%
extension of lifespan [NATURE; Tissenbaum,HA; 410:227-230 (2001)].
**LONGEVITY GENES AND DNA REPAIR**| image by Harold Brenner |
Experiments in which ***Drosophila*** **Sir2** expression was quadrupled
apparently led to a 57% extension of lifespan, with no further lifespan extension by CRAN.
Flies on CRAN showed an increase in Sir2 mRNA and a lifespan increase that could be
prevented by decreasing Sir2 gene
function [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Rogina,B;
101(45):15998-16003 (2004)](http://www.pnas.org/cgi/content/full/101/45/15998)]. ***Drosophila*** fed the histone
deacetylase inhibitor 4-phenylbutyrate showed up to 52% longer maximum lifespan. Gene
analysis showed repressed expression of some metabolism genes and increased expression of
genes for SOD, Elongation Factor−1-alpha (EF−1 α) & heat shock proteins,
among others [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Kang,H; 99(2):838-843
(2002)](http://www.pnas.org/cgi/content/full/99/2/838)].
In contrast to earlier research, however, a more careful analysis
of Sir2 overexpression in ***C. elegans*** and
***Drosophila*** either showed no increase in
lifespan [[NATURE; Burnett,C; 477:482-485 (2011)](http://www.ncbi.nlm.nih.gov/pubmed/21938067)],
or a more modest 10-13% increase in
lifespan [[NATURE; Viswanathan,M; 477:E1-E2 (2011)](http://www.ncbi.nlm.nih.gov/pubmed/21938026)].
Deacetylation of proteins (other than histones) can directly modify their activity.
Most mammalian histone deacetylase enzymes are not
NAD-dependent [[JOURNAL OF PHARMACEUTICAL SCIENCES; Hisahara,S; 98(3):200-204 (2005)](http://www.jstage.jst.go.jp/article/jphs/98/3/98_200/_article)].
A family of
NAD-dependent Sir2-like deacetylases in mammals called **sirtuins** includes SIRT1
in the nucleus, SIRT2 in the cytoplasm and SIRT3 in the mitochondria. The protein most
resembling yeast SIR2 in humans is **SIRT1**. Unlike yeast Sir2 (which exclusively
deacetlyates histones) SIRT1 has a wide range of
substrates [[GENES & DEVELOPMENT; Haigis,MC; 20(21):2912-2921 (2006)](http://genesdev.cshlp.org/content/20/21/2912)]
including [p53](https://en.wikipedia.org/wiki/TP53)
and [FOXO3 protein](https://en.wikipedia.org/wiki/TP53)
which SIRT1 silences by direct deacylation —
reputed to prevent "premature senescence"
and "premature apoptosis". Nonetheless, SIRT1 deacetylation of p53 has not
been shown to alter cell survival following DNA
damage [[MOLECULAR AND CELLULAR BIOLOGY; Solomon,JM; 26(1):28-38 (2006)](http://mcb.asm.org/cgi/content/full/26/1/28)].
Polyphenols such as [quercetin](../nutrceut/phytochemicals.html#quercetin),
[resveratrol](../nutrceut/phytochemicals.html#resveratrol)
(especially) and other sirtuin-activating compounds have been reported to extend the
lifespan of nematodes & fruit flies. Resveratrol was shown to extend lifespan of
nematodes by 10% and fruit flies by 29% without loss of fertility [NATURE;
Wood,JG; 430:686-689 (2004)]. No lifespan increase was seen in flies lacking functional
**Sir2** and no additional life extension was seen with CRAN. This led to the conclusion
that (unlike ***C. elegans*** **daf−2** mutations), the life-extending
benefits of **Sir2** operate by a similar mechanism as CRAN. But there is experimental
evidence contradicting this conclusion [SCIENCE; Kaeberlein,M; 312:1312 (2006)].
Resveratrol has also been shown to extend the lifespan of short-lived fish
([killifish](https://en.wikipedia.org/wiki/Killifish#In_lifespan_research))
nearly 60%
without loss of fertility [CURRENT BIOLOGY; Valenzano,OR; 16(3):296-300 (2006)], possibly
by increased sirtuin expression, but a number of other mechanisms are possible [MUTATION
RESEARCH; Kundu,JK; 555(1-2):65-80 (2004) and [JOURNAL OF BIOLOGICAL CHEMISTRY; Kaeberlain,M; 280(17):17038-17045 (2005)](http://www.jbc.org/cgi/content/full/280/17/17038)].
Analysis of the brain, kidney, liver and other tissues of rats subjected to 60% *ad
libitum* CRAN showed increased SIRT1 expression [SCIENCE; Cohen,HY; 305:390-392 (2004)].
Treatment of human embryonic kidney cells with resveratrol or transfection of those cells with
SIRT1 expression vector resulted in a dose-dependent reduction of **Bax** protein mediated
apoptosis [SCIENCE; Cohen,HY; 305:390-392 (2004)]. SIRT1 increases FOXO3's induction
of cell cycle arrest and resistance to oxidative stress, but inhibits FOXO3's induction of
apoptosis [SCIENCE; Brunet,A; 303:2011-2015 (2004)].
Methods of increasing NAD or activating sirtuins have been proposed to prevent
neurodegeneration [[SCIENCE; Araki,T; 305(5686):1010-1013 (2004)](http://www.sciencemag.org/cgi/content/full/305/5686/1010)]. Neurons are post-mitotic
(as are all cells in fruit flies and nematodes) so the anti-apoptotic effect of SIRT1 would have
to be the main pro-survival mechanism. In response to DNA damage,
SIRT1 may inhibit p53-mediated cell-cycle
arrest and apoptosis, but in response to TNF−α cytokine reduces NF−κB mediated
inhibition of cell-cycle arrest and
apoptosis [[THE EMBO JOURNAL; Yeung,F; 23(12):2369-2380 (2004)](http://www.nature.com/emboj/journal/v23/n12/full/7600244a.html)]. Resveratrol
similarly reduces NF−κB expression.
**Ku70** protein,
which functions in DNA repair, is normally bound tightly to **Bax** protein in the
cytoplasm, but in response to stress Ku70 is activated and releases Bax, which can then
move into the mitochondria to initiate apoptosis. SIRT1 reduces ku70 acetylation and thereby
opposes apoptosis [SCIENCE; Cohen,HY; 305:390-392 (2004)]. If SIRT1 were increasing
lifespan by resisting apoptosis, the effect would be similar to that seen in
p66shc mice. Human SIRT6 maintains telomere
integrity [[NATURE; Michishita,E; 452:492-496 (2008)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646112/)].
Sirtuins facilitate NHEJ (Non-Homologous End-Joining DNA
repair mechanisms for Double-Strand Breaks, **DSB**s) by an unknown
mechanism [[ACTA BIOCHIMICA POLONICA; Wojewodzka,M; 54(1):63-69 (2007)](http://www.actabp.pl/pdf/1_2007/63.pdf)].
ATM phosphorylation
of H2AX recruits SIRT1 to DSBs, which evidently assists in repair [CELL; Oberdoerffer,P;
135(5):907-918 (2008)]. Derepression of the genome at loci vacated by SIRT1 recruited by
genotoxic stress may lead to generalized dysdifferentiation associated with aging.
In vitro study of gene expression in neocortical tissue showed that more than two-thirds
of SIRT1-bound genes derepressed during aging were also derepressed by oxidative
stress [CELL; Oberdoerffer,P; 135(5):907-918 (2008)].
SIRT1 also represses the nuclear receptor **PPAR−γ** (Peroxisome
Proliferator-Activated Receptor−gamma), thereby triggering lipolysis and
loss of fat, suggestive of the life-extending benefits of fat reduction in FIRKO
mice. Treatment of fibroblasts with the SIRT1 activator resveratrol resulted in a
significant reduction of fat content [NATURE; Picard,F; 429:771-776 (2004)].
PPAR−γ inhibition has been used to block the development of insulin
resistance due to obesity and type 2
diabetes [[AMERICIAN JOURNAL OF PHYSIOLOGY; Miles,PDG; 284(3):E618-E626 (2003)](http://ajpendo.physiology.org/cgi/content/full/284/3/E618)],
suggestive of the idea that CRAN and the [metabolic syndrome](../health/MacroNut.html#syndrome) are opposite ends of a continuum.
[(return to contents)](#contents)
### XVIII. HORMONES AND AGING
A "neurohormonal clock" in the brain of mammals has been suggested
to influence aging through neurohormones.
Hormones alter the gene expression of DNA throughout the body. The
pituitary gland (the "master gland") under the influence of the
brain/hypothalamus can thus influence the physiology of all body cells.
When the pituitary gland of mammals is surgically removed and
supplements of essential hormones are given, maximum lifespan increases by
one third to one half. Such mammals voluntarily reduce their caloric intake,
which suggests that the life extension may be primarily due to CRAN
([Caloric Restriction with
Adequate Nutrition](../calories/calories.html)).
The hormones DHEA, melatonin, thyroid, and
somatotropin (Growth Hormone, **GH**) decline with
age. Women experience menopause, with the loss of progesterone and estradiol
secretion from the ovaries. Specific areas of the brain show
age-related declines in the levels of the neurotransmitters dopamine,
acetylcholine, norepinephrine, GABA and serotonin.
With aging there is a decline in both serotonin transporters [LIFE SCIENCES;
Yamamoto,M; 71(7):751-757 (2002)] and serotonin
receptors [[NEUROPSYCHOPHARMACOLOGY; Meltzer,MD; 71(7):751-757 (2002)](http://www.nature.com/npp/journal/v18/n6/abs/1395175a.html;jsessionid=C90DC8D122AD01015378F209DDDC5B18)].
[Serotonin](../science/anatmind/anatmd10.html#serotonin) is the precursor for melatonin in the brain.
**Decreased Anti-Diuretic Hormone (AVP)
effectiveness with age**| Decreased Anti-Diuretic Hormone (AVP) effectiveness with age |
Aging is associated with increasing secretion of the hormone
8−arginine vasopressin (**AVP**, also known as Anti-Diuretic Hormone or
simply vasopressin), and a decreasing ability of AVP to increase serum
[osmolality](../cryonics/protocol.html#diffusion). With age there is a decline in kidney AVP
receptors, which results in increased AVP secretion and decreased AVP
effectiveness [[AMERICAN JOURNAL OF PHYSIOLOGY; Tian,Y; 287(4):F797-F805 (2004)](http://ajprenal.physiology.org/cgi/content/full/287/4/F797)].
Nearly 10% of the elderly suffer from
[hyponatremia](http://en.wikipedia.org/wiki/Hyponatremia),
and nearly twice as many elderly nursing home residents suffer from that
affliction [JOURNAL OF THE AMERICAN GERIATRIC SOCIETY; Miller,M;
54(2):345-353 (2006)].
According to the **glucocorticoid cascade hypothesis**, glucocorticoid
steroid hormones show rising blood levels with age, which increasingly
damages feedback inhibition neurons in the
[hippocampus](http://www.benbest.com/science/anatmind/anatmd3.html#hippo), resulting in even
greater increases of blood glucocorticoid and a destructive feedback loop.
Glucocorticoid hormone (cortisol in humans) is a normal response to stress.
Cortisol mobilizes blood glucose and depresses the immune/inflammatory response,
among other effects. Although useful in emergencies, chronic stress can be
catabolic (destructive — Pacific salmon use glucocorticoids to self-destruct
after spawning). Physical & psychological stress causes the brain to release
**C**orticotropin **R**eleasing **F**actor (**CRF**) &
vasopressin — both of which stimulate pituitary release of
**A**dreno**C**ortico**T**ropic **H**ormone (**ACTH**).
ACTH causes the adrenal cortex to release glucocorticoids.
High blood levels of glucocorticoids are sensed by neurons in the
hippocampus, which signal the brain to release less vasopressin. The
involvement of hippocampal neurons makes sense because stressful situations
are often associated with vivid & detailed memories. Patients with major
depression can lose 20% of their hippocampal volume. Cortisol can
reduce neuron uptake of glucose by 15-25% — which can contribute to
neuron death [EXPERIMENTAL GERONTOLOGY 34:721-732 (1999)]. Moreover,
glucocorticoids reduce cellular SOD & glutathione peroxidase activity
in all brain areas [BRAIN RESEARCH 791:209-214 (1998)].
Although the glucocorticoid cascade hypothesis is not
a theory of aging in the sense of reducing lifespan, it does count as a theory
of brain aging — declining capacity for memory-formation in particular.
Blood glucocorticoid increases with age in rats, but humans normally do not
show increasing levels of glucocorticoid until the late 70s or 80s.
About half of
[Alzheimer's Disease](../lifeext/Alzheimer.html)
patients show significantly elevated
cortisol, however. Most people do normally show
increasing number (and perhaps hypertrophy) of neurons in the
**P**ara**V**entricular **N**ucleus (**PVN**) — which
expresses both CRF & vasopressin — as they age. Evidence suggests
an inverted U−shaped relationship between cortisol & cognition — and
that sustained higher cortisol levels can lead to a non-Alzheimer's dementia
in humans [JOURNAL OF PSYCHIATRIC RESEARCH 35:127-145 (2001)]. Estrogen
can prevent or even reverse cortisol-induced brain damage [BRITISH
JOURNAL OF CLINICAL PHARMACOLOGY 52:647-653 (2001)].
Much antioxidant protection in the brain is due to **bilirubin** which is produced
by **Heme Oxygenase** (**HO**) enzyme, particularly in the hippocampal neurons.
HO expression declines with age in the rat brain, and this decline has been linked
to elevated glucocorticoid expression [JOURNAL OF NEURAL TRANSMISSION; Ewing,JF;
113(4):439-454 (2006)]. Additionally, HO has antiapoptotic effects which are
independent of the antioxidant effects of bilirubin [KIDNEY INTERNATIONAL;
Nath,KA; 70(3):432-443 (2006)]. (For more on the antioxidant effects of bilirubin see
[Antioxidant Enzymes](../nutrceut/AntiOxidants.html#enzymes).)
**Some Hormone/Cytokine changes with age**| Some Hormone/Cytokine changes with age |
Some critics have pointed-out that CRAN animals show elevated glucocorticoids, but it
should come as no surprise that calorie-restriction is stressful. In fact, the glucocorticoid
cascade hypothesis raises the worrisome possibility that CRAN could prolong lifespan while
simultaneously undermining memory capabilities. But experiments on CRAN animals have not
shown learning deficiencies, quite the opposite.
Humans and other primates are the only species that produce & secrete
the hormone [**D**e**H**ydro**E**pi**A**ndrosterone](../nutrceut/DHEA.html) (**DHEA**)
and it's sulfate (**DHEA−S**) in quantities surpassing those of any other steroid.
DHEA levels peak in the late 20s and decline to 10% of the peak by age 80.
DHEA may protect against the harmful effects of cortisol while contributing to
androgen & estrogen synthesis in peripheral tissues, promoting lean body mass,
reducing depression and improving immune function [EXPERIMENTAL GERONTOLOGY
33(7/8):713&897 (1988)].
Growth Hormone (**GH**) also declines with age (about 14% per decade after
age 25), which is blamed for increased fat deposition, loss of muscle mass and
bone demineralization. There is evidence that GH replacement can improve cardiovacular
health, boost immune function and improve cognitive function in older adults, but there
is also the danger that GH replacement can increase insulin resistance and cancer risk.
The idea of restoring all hormones and growth factors to youthful levels
as a means of rejuvenation has a strong intuitive appeal, but hormones often have the
risk of promoting cancer growth. Given the fact that cancer incidence increases with
age, declining hormone levels may even contribute to elderly survival. Only
when cancer is eliminated will replacement of all age-declining hormones be safe.
Even then, however, for cases where declining receptor sensitivity rather that declining
hormone release are associated with age (as with AVP), hormone replacement will
not get to the root of the problem — and can be harmful without causing cancer.
[For more about DHEA and GH, see [DHEA Hormone Replacement](../nutrceut/DHEA.html) and [Growth Hormone (GH/IGF−1) Replacement]](../nutrceut/GH_IGF1.html).
[For more about sex hormone replacement, see [Sex Hormone Replacement in Older Adults]](../health/SexHormR.html)
[(return to contents)](#contents)
### XIX. THE IMMUNE SYSTEM AND AGING
According to the "immune system theory of aging", many aging
effects are due to the declining ability of the immune system to differentiate
"foreign" from "self" proteins. Not only does the immune system become less
capable of resisting infection & cancer, but declining cell function could
be due to attacks by the immune system against native tissues. Arthritis, psoriasis and
other autoimmune diseases increase with age. There is evidence
that histocompatability genes, genes affecting DNA repair and genes for SOD
production — all of which affect longevity — are located close together on human
chromosome 6.
Leukocytes (white blood cells), which form the basis of the immune system (along with
complement proteins), are roughly 65% granulocytes (mostly neutrophils), 5% monocytes
(which can become macrophages) and 30% lymphocytes. Lymphocytes can be subclassified as
B−lymphocytes (**B−cells**) or T−lymphocytes (**T−cells**) based on whether they mature
in **B**one marrow or the **T**hymus gland (all lymphocytes originate in bone marrow).
**Antigens** are molecular portions of pathogens that act as identifiers.
**B−cells** generate antibodies ("humoral immunity") against antigens, whereas
**T−cells** directly bind to antigens ("cellular immunity").
The thymus gland of the immune system reaches its greatest weight
during puberty, and shrinks thereafter, with lymphoid tissue being
replaced by fat. The shrinking of the thymus gland proceeds far more rapidly than the
progress of aging — at age 50 the thymus of humans is typically only 5−10%
of its original mass. Nonetheless, T−cells remain fairly constant over most of adult life
due to peripheral proliferation (although proliferation declines in the elderly).
Because the thymus is the organ in which T−cells "matures", once
maturation occurs most of the work of the thymus is done. In the maturing T−lymphocyte
system, the thymus creates a broad diversity of T−cells, each of which is programmed to
recognize and combat a different antigen. T−cells which would combat self-substances
are eliminated by apoptosis.
The immune system uses
***proliferation*** & ***apoptosis*** to create & refine T−cells.
The immune system uses **clonal expansion** (rapid multiplication of lymphocytes
of a single "clone" against a single antigen) & apoptosis
to control the numbers of T−cells available to fight specific antigen threats.
Injecting the protein
***Apo−1*** into a cell will trigger apoptosis. But the protein
***Bcl−2*** can rescue a cell from apoptosis. With aging, mature T−cells
increasingly manifest apoptosis for reasons that seem to be unrelated to decreased
***Bcl−2*** expression or oxidative stress [MECHANISMS OF AGING AND DEVELOPMENT;
Phelouzat,M; 88:25-38 (1996)].
T−lymphocytes that have not encountered an antigen since creation
are called **naive T−cells**, whereas T−lymphocytes that have
been clonally expanded to fight an invading antigen are called
**memory T−cells**. T−cells of the elderly have a much higher ratio
of memory T−cells to naive T−cells than younger people. Old memory T−cells have
less [CD28](http://en.wikipedia.org/wiki/CD28)
surface protein than young memory T−cells and are thus less able to divide when
presented with antigen [JOURNAL OF IMMUNOLOGY; Engwerda,CR; 152:3740-3747 (1994)]. CD28
ligation is required for production of IL−2 cytokines. The elderly
memory T−cells have short telomeres and are thought to accumulate because
of increasingly defective apoptosis [IMMUNOLOGIC RESEARCH 21(1):31-38 (2000)].
Two predominant forms of T−cells are **cytotoxic T−cells** (with
[**CD8**](http://en.wikipedia.org/wiki/CD8)
surface receptors) and **helper T−cells** (with
[**CD4**](http://en.wikipedia.org/wiki/CD4) surface receptors).
The cytotoxic T−cells attack bacteria or cancerous cells by punching holes in
the cells and injecting them with toxic proteins. The helper T−cells secrete
***growth factors*** (**cytokines**) that foster the clonal expansion of other
T−cells and/or of antibody-producing cells (the **B−lymphocytes**). Helper
T−cells are more numerous in youth & maturity, but in the elderly the ratio of
CD8 to CD4 cells increases. CD8 T−cells become more resistant to apoptosis with aging,
whereas CD4 cells become more susceptible to apoptosis.
[Cytomegalovirus](http://en.wikipedia.org/wiki/Cytomegalovirus)
prevalence significantly increases in the elderly, and may be responsible for much of the
skewed CD8:CD4 ratio of advanced
age [[JOURNAL OF IMMUNOLOGY; Hadrup,SR; 176(4):2645 (2006)](http://www.jimmunol.org/cgi/content/full/176/4/2645)].
Cytomegalovirus infection increases with age in
humans [[CLINICAL INFECTIOUS DISEASES; Staras,SAS; 43(9):1143-1151 (2006)](http://www.ncbi.nlm.nih.gov/pubmed/17029132)],
primarily infects antigen-presenting cells & can increase inflammatory
cytokines [[REVIEWS IN MEDICAL VIROLOGY; Varani,S; 19(3):131-145 (2009)](http://www.ncbi.nlm.nih.gov/pubmed/19367559)],
and is associated with
immunosenescence [[CURRENT OPINION IN IMMUNOLOGY; Derhovanessian,E; 21(4):440-445 (2009)](http://www.ncbi.nlm.nih.gov/pubmed/19535233)].
Naive CD4 cells decline rapidly after
age 65 [[JOURNAL OF IMMUNOLOGY; Naylor,K; 174(11):7446-7452 (2005)](http://www.jimmunol.org/cgi/content/full/174/11/7446)].
There are two types of helper T−cells, designated **TH1** (type 1)
and **TH2** (type 2). The TH1 cells promote growth of
T−lymphocytes with the cytokine **InterLeukin−2** (**IL−2**), whereas the
TH2 cells promote growth of B−lympocytes with the cytokine
**InterLeukin−4** (**IL−4**). TH1 cells are more prominent in
autoimmune infections, whereas TH2 cells are more prominent in viral infections.
In youth & maturity the TH1 cells predominate, but in the elderly the
TH2 cells predominate [MECHANISMS OF AGING AND DEVELOPMENT 94:1-5 (1997)].
Moreover, aging is accompanied by a significant loss of IL−2 as well as of IL−2 receptors
— a phenomenon thought to be responsible for the significant decline of **proliferation**
(clonal expansion) in response to antigens seen with aging [SCIENCE 273:70-74 (1996)].
The decline of T−cell activation due to reduced IL−2 production is at least partially due to
oxidation-damaged proteasomes being less capable of inducing the gene transcription factor
NFκB [CELLULAR IMMUNOLOGY 192:167-174 (1999)].
Proliferation of T−cells in response to antigenic or mitogenic (cell-division stimulating)
signals also declines with aging — apparently due to to decline in activity of the **M**itogen
**A**ctivating **P**rotein **K**inase (**MAPK**) cascade which causes cell surface
signals to alter gene expression. CRAN ([Caloric Restriction with Adequate Nutrition](../calories/calories.html)) significantly reduces the
decline of MAPK activity associated with aging [PROCEEDINGS OF THE SOCIETY FOR
EXPERIMENTAL BIOLOGY AND MEDICINE 223:163-169 (2000)]. But
[selenium supplementation](../nutrceut/Selenium.html) has been shown
to restore lymphocyte proliferation in aged mice to that of normal young adults [PROCEEDINGS OF
THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE; Roy,M; 209(4):369-375 (1995)].
The combination of low T−cell proliferation and low CD4/CD8 ratio was highly predictive of low
2−year survival in a study of people in the 86−92 age range [JOURNALS OF GERONTOLOGY
50A(6):B378-B382 (1995)]. [Melatonin](../nutrceut/Melatonin.html) elevates
the CD4/CD8 ratio [[IMMUNITY & AGEING; Srinivasan,V; 2:17 (2005)](http://www.immunityageing.com/content/2/1/17)]. Immune function is very
important for the elderly because
infection causes an increasing percentage of deaths for those over 80 years of
age [JOURNALS OF GERONTOLOGY 52A(1):B67-B77 (1997)] and AMERICAN JOURNAL OF
MEDICINE; 114:365-369 (2003)].
[Regulatory T−cells](http://en.wikipedia.org/wiki/Regulatory_T_cell)
that suppress T−cell-mediated autoimmune diseases in humans decline with
age [[JOURNAL OF NEUROSCIENCE RESEARCH; Tsaknaridis,L;
74(2):296-308 (2003)](http://www.ncbi.nlm.nih.gov/pubmed/14515359)].
**Natural Killer** (**NK**) cells differ from cytotoxic T−cells by the ability
to lyze pathogenic cells without the need of antigens. NK cells decline in activity
with age, but this decline is compensated for by an increase in NK cell numbers. In
centenarians, however, no decline in NK activity has been seen — nor was there a decline
in youthful CD8/CD4 cells [IMMUNOLOGY TODAY; Franceschi,C; 16(1):12-16 (1995)].
**B−cells** from older animals produce less antibody and express less of the surface
CD40 protein which causes B−cell activation and differentiation. The decline in T−cell
activity with age is responsible for most of the decline in B−cell numbers and activity.
**Macrophages** are immune-system cells that "eat" foreign
particles (including bacteria) and digest the particles in lysosomes. **Monocytes**
are the small blood stream cells that swell to become macrophages after migrating into
tissues. Monocytes from elderly humans have a greatly reduced capacity to produce the
cytokine **InterLeukin−1** (**IL−1**) and the toxic free radicals that
macrophages use to kill foreign or cancerous cells [THE JOURNAL OF IMMUNOLOGY
154:832-843 (1995)]. Nonetheless, the superoxide, hydrogen peroxide, hydroxyl ions &
nitric oxide produced by neutrophils & macrophages to kill bacteria can attack native
tissues in age-associated chronic inflammation. The reactive products of nitric oxide
and oxygen species inhibit PARP-mediated DNA repair [FREE RADICAL BIOLOGY &
MEDICINE 35(11):1431-1438 (2003)].
Some of the decline in immune function in the elderly may be due to protein
cross-linking in tissues & blood vessels reducing immune-cell mobility and
access to infected areas. Poor nutrition in the elderly is also a factor.
Supplements consisting of recommended dietary allowances of nutrients
(plus extra Vitamin E & beta-carotene) significantly improved the
immune status of elderly subjects [THE LANCET 340:1124-1127 (1992)].
Supplementation with the steroid hormone [**D**e**H**ydro**E**pi**A**ndrosterone](../nutrceut/DHEA.html) (**DHEA**, a hormone
that dramatically declines with age) increased IL−2 & Interferon-gamma
activity in mice [THE JOURNAL OF INFECTIOUS DISEASES 167:830-840 (1993)].
Vulnerability to death by influenza & pneumonia increases rapidly with age in the United
States. A person aged 50−64 is nearly ten times more likely to die from an influenza-associated
death as a person in the 5−49 age group. And a person over 65 is over ten times more likely
to die from an influenza-associated death as a person in the 50−64 age group. A person over
85 is about 16 times more likely to die an influenza-associated death as a person in the 65−69
age group [[JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION; Thompson,WW; 289(2):179-186 (2003)](http://jama.ama-assn.org/cgi/content/full/289/2/179)].
Vaccination of the elderly reduces influenza-associated death by
50% [[ARCHIVES OF INTERNAL MEDICINE; Hak,E; 165(3):274-280 (2005)](http://archinte.ama-assn.org/cgi/content/full/165/3/274)].
[(return to contents)](#contents)
### XX. INFLAMMATION AND AGING
With aging the body contains increasing quantities of
[proinflammatory
cytokines](../health/MacroNut.html#mechanisms) such as TNF−α, IL−1 and IL−6, which
is positively associated with cardiovascular disease
mortality [[IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA; Bruunsgaard,H;
23(1):15-39 (2003)](http://www.ncbi.nlm.nih.gov/pubmed/12645876)]. The increase in memory cells results in an increase in
the cytokines IL−4 & IL−10 that are produced by the memory cells.
Lifetime exposure to infectious disease reduces lifespan
by accelerated immunosenescence [FEBS LETTERS; Martinis,MD; 579:2035-2039 (2005)] and
chronic inflammation [SCIENCE; Finch,CE; 305:1736-1739 (2004)]. Chronic inflammation
is implicated in atherosclerosis, arthritis, [Alzheimer's Disease](../lifeext/Alzheimer.html), [cancer](../health/cancer.html), [the metabolic syndrome (type 2 diabetes)](../MacroNut.html#syndrome) and numerous other
afflictions affecting the elderly. Inflammation is probably not the major cause of
the damage & degeneration of aging, but it contributes to the damage. Free radicals
and oxidized glycation products (AGEs) are contributers to chronic inflammation.
**Effects of Aging and Calorie Restriction (CR)**| Aging and Calorie Restriction (CR) Effects |
**GC=GlucoCorticoids**
Aging is associated with increasing activity of the
[pro-inflammatory transcription factor
NF-κB](../health/cancer.html#inflame) (**NF−κB**).
NF−κB is normally bound to **IκB** protein in the cytoplasm,
but is released to enter the nucleus when infection, oxidative stress or pro-inflammatory
cytokines cause [ubiquitination
and subsequent protease degradation](#protein) of IκB. NF−κB increases transcription of genes
coding for TNF−α and IL−1, which can result in a positive feedback loop. The
ability of free radicals (**ROS**, Reactive Oxygen Species) to cause NF−κB release
and the production of ROS by inflammation also results in a positive feedback loop.
NF−κB and TNF−α are central to the aging-associated increase
in chronic inflammation. Although glucocorticoids are increased in aging & CRAN and can
inhibit NF−κB, stimulation of NF−κB by stressors predominates. Not
only does NF−κB release increase with age, but aging results in NF−κB binding more
strongly to DNA [[BIOCHEMICAL JOURNAL; Helenius,M; 318(Pt 2):603-608 (1996)](http://www.biochemj.org/bj/318/0603/bj3180603.htm)].
Age-associated increases in [ceramide](http://en.wikipedia.org/wiki/Ceramide) results in increased NF−κB
activation [[THE JOURNAL OF IMMUNOLOGY; Wu,D; 179(7):4829-4839 (2007)](http://www.jimmunol.org/cgi/content/full/179/7/4829)].
NF−κB induced chronic inflammation in combination with its ability to
suppress apoptosis (inhibiting the elimination of cancer cells) often leads to
cancer [NATURE IMMUNOLOGY; Karin,M; 3(3):221-227 (2002)]. Cancer can also be
initiated by NF−κB induction of inducible Nitric Oxide Synthetase (**iNOS**),
leading to DNA damage, and the inhibition of apoptosis by NF−κB again
favors cancer [NATURE REVIEWS, IMMUNOLOGY; Karin,M; 5:749-759 (2005)].
**TNF−α products**| TNF−α products |
Aside from the induction of **TNF−α** (Tumor Necrosis Factor-alpha) by
NF−κB, [TNF−α is produced by visceral fat](../health/MacroNut.html#mechanisms). Obese people can
produce twice as much TNF−α as lean people produce.
White adipose tissue attracts macrophages, which produces
the inflammatory agents (like TNF−α) associated with obesity-induced insulin
resistance [[JOURNAL OF CLINICAL INVESTIGATION; Xu,H; 112(12):1821-1830 (2003)](http://www.jci.org/articles/view/19451)].
Surgical removal of visceral fat (but not subcutaneous fat) extends the mean
and maximum lifespan of rats [ [BIOCHEMICA ET BIOPHYSICA ACTA; Huffman,DM; 1790(10):1117-1123 (2009)](http://www.ncbi.nlm.nih.gov/pubmed/19364483)].
TNF−α can induce apoptosis, but only if protein synthesis is
inhibited [SCIENCE; Beg,AA; 274:782-784 (1996)].
TNF−α upregulates NF−κB and **IL−6** (InterLeukin−6).
IL−6 upregulates pro-inflammatory cytokine **IL−1** and induces the liver to produce
the inflammatory protein **CRP** (C−Reactive Protein). Proinflammatory cytokines
have been shown to induce cellular senescence [FREE RADICAL RESEARCH; Sasaki,M;
42(7):625-632 (2008) and CELL; Kuilman,T; 133(6):1019-1031 (2008)]. But IL−6
but also induces production of the anti-inflammatory cytokine **IL−10** while
inhibiting TNF−α. IL−10 (which inhibits TNF−α production)
is produced in larger quantities when exogenous S-adenosylmethionine is
administered [[AMERICAN JOURNAL OF PHYSIOLOGY; Song,Z; 284(6):G949-G955 (2003)](http://ajpgi.physiology.org/cgi/content/full/284/6/G949)].
CRP is an important risk factor for myocardial infarction
(heart attack). A four-year study of women showed those in the highest quarter of
blood CRP had 15.7 times greater risk of developing type 2 diabetes as those in
the lowest quarter [JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION; Pradham,AD;
286(3):327-334 (2001)]. In a study of men, those in the highest quarter of blood CRP
had 3 times the risk of developing dementia as those in the lowest quarter [ANNALS
OF NEUROLOGY; Schmidt,R; 52(2):168-174 (2002)].
Increasing plasma levels of pro-inflammatory cytokines with aging can induce
a stress response that is responsible for the increased plasma levels of cortisol
associated with aging [[INFLAMMATION RESEARCH; Sergio,G; 57(12):558-563 (2008)](http://www.ncbi.nlm.nih.gov/pubmed/19109735)].
Although elevated cortisol is generally anti-inflammatory in the periphery,
cortisol can be pro-inflammatory in the hippocampus and cerebral
cortex [[BRAIN, BEHAVIOR, AND IMMUNITY; Sorrells,SF; 21(3):259-292 (2007)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1997278/)].
Exercise can be very anti-inflammatory by increasing muscle-derived IL−6
production (which is independent of TNF−α) and reducing
CRP [[JOURNAL OF APPLIED PHYSIOLOGY; Peterson,AWW; 98(4):1154-1162 (2005)](http://jap.physiology.org/cgi/content/full/98/4/1154)].
Adequate [sleep](../health/sleep.html)
can reduce TNF−α and IL−6 secretion (both of which
induce sleepiness & fatigue). Reduction of IL−6 production by the
administration of sex steroids has been suggested as a means of reducing problems
with sleepiness & fatigue in the
elderly [[THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM;
Vgontias,AN; 88(5):2087-2095 (2003)](http://jcem.endojournals.org/cgi/content/full/88/5/2087)]. DHEA can also reduce
IL−6
production [[THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM;
Straub,RH;83(6):2012-2017 (1998)](http://jcem.endojournals.org/cgi/content/full/83/6/2012)].
CycloOXygenase (COX) enzyme activity increases with age, thereby increasing the
production of prostaglandins that inhibit T−cell proliferation. Increased levels
of hydrogen peroxide probably are responsible for the age-related increase in COX
activity, indicated by the fact that [Vitamin E](../nutrceut/VitaminE.html) attenuates COX activity and restores T−cell
proliferation [[AMERICIAN JOURNAL OF PHYSIOLOGY; Wu,D;
275(3 Pt 1):C661-C668 (1998)](http://ajpendo.physiology.org/cgi/content/full/275/3/C661)].
[Advanced Glycation
End-products (AGES)](../health/MacroNut.html#AGEs) not only originate from metabolism,
but can be ingested in diet or tobacco smoke and contribute significantly to
inflammation. AGEs can activate
NF−κB [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Vlassara,H;
99(24):15596-15601 (2002)](http://www.pnas.org/cgi/content/full/99/24/15596)]. High blood insulin potentiates NF−κB
in a dose-dependent
manner [[CIRCULATION RESEARCH; Golovchenko,I;87(9):746-752 (2000)](http://circres.ahajournals.org/cgi/content/full/87/9/746)].
Increased NF−κB activity by AGEs is often mediated by a Receptor
for AGE (**RAGE**), which can also be activated by
TNF−α [[JOURNAL OF BIOLOGICAL CHEMISTRY; Tanaka,N; 275(33):25781-25790
(2000)](http://www.jbc.org/cgi/content/full/275/33/25781)]. NF−κB activated by oxidative stress or AGEs upregulates the expression
of RAGE (more AGE receptors), creating a positive feedback loop that worsens chronic
inflammation [[CIRCULATION RESEARCH; Schmidt,AM; 84(5):489-497 (1999)](http://circres.ahajournals.org/cgi/content/full/84/5/489)].
Even though age-associated chronic diseases are important components of
[segmental progerias](#progeria) , they are often
dissociated from aging *per se* because those people who achieve
maximum lifespan typically do not die of these diseases. The role of controllable
risk factors like obesity, exercise, AGE ingestion and Vitamin E supplementation
would also tend to dissociate inflammation and chronic disease from a central
role in the essential aging process. Nonetheless, these chronics diseases
***are*** aging-associated and it is likely that inflammation plays
some role in the degenerative & damaging processes known as aging.
[(return to contents)](#contents)
### XXI. ACCUMULATION OF TOXINS AND CHEMICAL GARBAGE
Many chemicals accumulate in the cells with age, including toxic
& inert substances from the exterior and similar substances arising as
byproducts of cellular metabolism [notably Advanced Glycation End-products (AGEs) and
lipid peroxidation debris]. Fat-soluble substances (such as DDT &
PCBs) are particularly slow to be eliminated. Iron tends to accumulate in cell nuclei
with aging, as does aluminum. Aluminum transforms metabolically active DNA
into an inert state. Lead also accumulates in cells, and is neurotoxic.
Cytochrome P−450 detoxification enzymes of the liver (which have maximal
light absorption at 450 nanometer wavelength) decline with age. In the 1976 to
1980 period, the 15% of US population with the highest blood levels of
lead had 49% higher cardiovascular mortality and 68% higher
cancer mortality [[ARCHIVES OF INTERNAL MEDICINE; Lustberg,M; 162(21):2443-2449 (2002)](http://archinte.ama-assn.org/cgi/content/full/162/21/2443)].
Non-dividing cells (muscle cells, heart muscle cells and neurons) are
not susceptible to the Hayflick Limit. Nor is double-chromosome damage of as
great concern in non-dividing cells as it is for dividing cells. But for
non-dividing cells that cannot be replaced — heart muscle cells and neurons —
the accumulation of cellular garbage may be a very significant factor in
cellular aging. Species survival may be thus dependent on the creation of new
organisms once the old ones have accumulated too much chemical garbage to
be functional.
Of particular note is **lipofuscin** (age pigment), which can
accumulate in large quantities in non-dividing cells. Lipofuscin is regarded as a
product of **lysosomes** — organelles containing hydrolytic enzymes
to degrade proteins, lipids and damaged organelles. As production of
lysosome enzymes decline with age — and as lysosomes engulf increasingly
cross-linked proteins & lipids that are resistant to enzyme
degradation — dysfunctional lysosomes (bloated with indigestible contents)
accumulate in cells containing **lipofuscin granules**. Lipofuscin granules
(engorged lysosomes) are
characterized by a single membrane envelope, enclosing yellowish-brown
material that can autofluorescence.
Inhibitors of **proteases** (enzymes that degrade protein) and Vitamin E
deficiency result in lipofuscin-like cellular residues — a clue to
the origin of lipofuscin. There is evidence that lipofuscin formation
inhibits protein degradation, thereby creating a vicious cycle that
promotes its own formation [EXPERIMENTAL GERONTOLOGY 36:475-486
(2001)]. In contrast to ceroids — which rapidly accumulate extra− & intra−
cellularly in pathologic conditions — lipofuscin accumulates slowly, universally and
specifically accumulates in lysosomes [ANNALS OF THE NEW YORK ACADEMY OF SCIENCES; Portas,EA;
959:57-65 (2002)]. The composition of lipofuscin — nearly half protein, one-third
carbohydrate and the rest lipid — indicates that it is primarily composed of AGEs rather
than lipid peroxidation products [BIOCHEMICAL AND BIOPHYSICAL RESEARCH
COMMUNICATIONS 236:327-332 (1997)].
Lipofuscin is normally diluted-out of dividing cells, although it is seen
in increasing amount in fibroblasts nearing the Hayflick Limit. Lipofuscin
accumulation in the non-dividing cells of the brain&heart is very
prominent and is, in fact, regarded as a biomarker of aging. Lipofuscin
accumulation in retinal pigment epithelial cells may lead to age-related
macular degeneration, the leading cause of blindness in the developed world.
The fact that lipofuscin accumulates at a higher than normal rate in
[Alzheimer's Disease](../lifeext/Alzheimer.html)
and the fact that the disease is also characterized by abnormal
tau-protein and amyloid-protein suggests that creation of defective protein
and/or problems with removal of defective protein could be the underlying
cause of Alzheimer's Disease.
Aging due to free-radicals & glycation of macromolecules other than DNA would be
expected more in non-dividing cells than dividing cells — most notably in neurons. That
lipofuscin is a component of neuron aging due to free-radical damage is indicated by the
high levels of metals (especially iron) in lipofuscin. Oxidative stress has been shown to
promote lipofuscin formation, whereas antioxidants reduce lipofuscin formation [FREE
RADICAL BIOLOGY & MEDICINE 33(5):611-619 (2002)]. Although antioxidants cannot extend
maximum lifespan of organisms as a whole, they may extend the maximum lifespan of neurons
or even the entire brain. If so, antioxidants combined with organ replacement could be
a means of extending maximum lifespan.
Lysosomes are normally responsible for degradation of aging mitochondria. But as
lysosomes become increasingly dysfunctional due to accumulation of indigestible lipofuscin,
cells become increasingly populated with aging, swollen mitochondria that produce less
energy and more superoxide. Reactive oxygen species produce more aldehydes and more
aldehyde-bridges between proteins, resulting in more
lipofuscin [[EUROPEAN JOURNAL OF BIOCHEMISTRY 269(8):1996-2002 (2002)](http://content.febsjournal.org/cgi/content/full/269/8/1996)]. There
is thus a positive feedback loop of lipofuscin production, impaired lysosomes,
dysfunctional mitochondria and aldehyde formation.
[(return to contents)](#contents)
### XXII. CANCER AND AGING
As a cause of death the relative incidence of cancer increases exponentially
to age 65 and decreases thereafter. At age 65, 30% of North
American deaths are due to cancer, whereas at age 80 only 12% of
deaths are due to cancer — mostly because the relative increase
of cardiovascular and [Alzheimer's Disease](../lifeext/Alzheimer.html) is faster than the increase
in cancer with age. Nonetheless aging is a major risk factor for
cancer, and aging is associated with cancer.
But aging can also be distinguished from cancer, much as with other
diseases associated with aging such as atherosclerosis, Alzheimer's Disease,
osteoporosis and arthritis. In children, cancers are predominantly leukemias, lymphomas
and sarcomas, whereas 80% of adult cancers in the United States are carcinomas.
Nearly 90% of mice die of cancer, with about 2/5 of those cancers being lymphomas
in males and about 3/5 lymphomas in females. About 30% of male mouse cancers are
carcinomas and about 40% are sarcomas [RADIATION RESEARCH; Tanaka,IB;
167(4):417-437 (2007)]. In Werner's Syndrome sarcomas (connective tissue
malignancies, usually) are more common than carcinomas. As with the mouse, this may
be due to cellular immortalization by ALT rather than telomerase. These patterns do not
indicate a simple relationship between aging and cancer.
That there is a distinction between aging and
cancer is suggested by the fact that ionizing radiation increases cancer rate,
but has less (if any) effect on the rate of aging. Atomic bomb
survivors [RADIATION RESEARCH; Preston,DL; 160(4):381-407 (2003) and
populations living near a nuclear test site [RADIATION RESEARCH;
Bauer,S; 164(4 Pt 1):409-419 (2005)] showed increased noncancer
mortality from aging-associated diseases (stroke, heart disease, respiratory
disease), but there is no proof that this constituted accelerated aging.
Experimental animals subjected to chronic sublethal
[ionizing radiation](http://www.health.gov.au:80/hfs/arpansa/is_rad.htm) (alpha−, beta−, gamma− & X−rays that cause
atoms & molecules to form ions) have shown generalize atrophy
("premature aging") and shortened lifespans,
but single X−ray & ionizing radiation exposures have more noticeably
increased kidney degeneration and cancer (especially leukemia). Other mutagens
increase the risk of tumor-formation without reducing maximum lifespan. These results
indicate that spontaneous mutations & chromosome breakage are not normal contributors
to aging. Mutations due to ionizing radiation are qualitatively different from those
occurring "spontaneously" with the passage of time [MUTATION RESEARCH
375:37-52 (1997)]. Mammals with longer lifespans have been shown to have more
efficient DNA repair of gamma-radiation [EXPERIMENTAL GERONTOLOGY
37:1203-1205 (2002)]. Nonetheless, the view that ionizing radiation causes
accelerated aging is not easily
dismissed [[AGING; Richardson,RB; 1(11):887-902 (2009)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815743/)].
Cancer is a disease of DNA, whereas aging is a disease of all organs, tissues,
cells and macromolecules. Most cancers are caused by chemical carcinogens, which may
result in DNA damage different from DNA damage associated with aging.
Cancer is a disease of dividing cells — especially the
rapidly dividing cells of the epithelium & blood-forming tissues. Non-dividing cells
like neurons or muscle cells don't become cancerous, but aging affects all tissues.
A study of 15 rodent species showed that telomerase repression is a feature of
large size rather than long life, suggesting that tumor initiation usually occurs
during growth and
development [[AGING CELL; Seluanov,A; 6(1):45-52 (2007)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693359/
TARGET=)]. Telomerase repression
rather than replicative senescence can be the primary anti-cancer mechanism.
DNA must ultimately be responsible for the great variation of maximum lifespan
between species. But in this respect DNA (the genome) partly is responsible for the production
of reactive oxygen species as well as for the capacity of tissues to withstand oxidative
stress & glycation as well as other chemical challenges. If aging is distinguished
from cancer by toxin/garbage accumulation and by damage to all macromolecules rather
than just DNA, it is nonetheless true that the DNA damage associated with cancer is
at least a ***component*** of aging. This view is supported by the apparent
correlation between maximum lifespan and DNA repair capability seen in species comparisons
— as well as by the signs of accelerated aging seen in many DNA repair diseases.
Clues about the molecular mechanisms of aging & cancer in general could be gained
by comparative analysis of the mechanisms of segmental progerias leading to specific cancers
& specific manifestations of aging. XP, AT & Werner's Syndrome are segmental
progerias due to defective NER, defective cell cycle control & defective recombination
(respectively) leading to high rates of skin cancer, leukemia & sarcomas (respectively).
The cancer symptoms are more prominent with XP & AT, whereas the progeria is more
prominent with Werner's Syndrome. Down's Syndrome & Hutchinson-Gilford Syndrome are
segmental progerias not particularly associated with high cancer risk. Defective DNA
mismatch repair leads to a form of colon cancer (HNPCC) without symptoms of accelerated
aging.
What is the relative contribution of reduced vulnerability to cancer due to reduced
Insulin-like Growth Factor−1 (IGF−1) to the extended lifespan of dwarf mice and to what
extent or by what mechanism is the rate of aging slowed?
Dietary factors, smoking and environmental chemicals can play a significant
role in the incidence of cancer, as indicated by the fact that breast
cancer in North American women is ten times more common than for women
in Japan. And dietary antioxidants — if not supplemental — appear to reduce
the risk of cancer. Environmental factors associated with aging
or maximum lifespan might cause increased glycation, generalized macromolecule damage
and lipofuscin accumulation along with DNA damage.
But in the absence of other diseases, there is a general
and exponential increase in the likelihood of contracting cancer
as a subject (human or other mammal) ages. There is an increased
cumulative effect of DNA mutation and a decline in immune-system
function with age. Nonetheless, the pattern of cancer increase associated with
aging is very different from immune deficiency disease. Whales have 600 times
as many cells as humans yet suffer no greater incidence of cancer. It is
improbable that whales have an immune system that is 600 times better than
that of humans. Whales must have other special defenses against cancer (which would
be well worth learning to understand). The high rate of cancer in rodents is not
surprising in light of the proclivity to immortalization associated with their
telomeres. But the capacity of mammalian species to detoxify the
[carcinogenic chemical](../health/cancer.html#chemicals)
benzo(a)pyrene to a water-soluble form also correlates well with maximum
lifespan [EXPERIMENTAL CELL RESEARCH 116:359-364 (1978)].
DNA damage due to mutagens more readily leads
to cancer, but defective DNA repair more readily leads to aging. Nearly all of the
"accelerated aging" diseases involve defective DNA repair. Better DNA
repair allows the deer mouse to live much longer than the house mouse. It may be
that mutagens damage both DNA as well as cellular defenses against DNA damage,
but that when DNA repair is defective cells can respond by inducing cellular
senescence or apoptosis — preventing cancer, but accelerating aging. With aging the
declining efficiency of cellular mechanisms means that there is a decreasing
likelihood that cancerous cells will be eliminated by apoptosis.
For technical details about the nature of cancer (and
methods of prevention) — see my essay
[Cancer Death](../health/cancer.html).
[(return to contents)](#contents)
### XXIII. BIOMARKERS OF AGING
Individuals of different species seem to age at different rates for different reasons.
Laboratory studies of lifespan is currently only feasible for short-lived species, but if
some **biomarker** could be found for determining **biological age** (rather than
**chronological** age) then human lifespan studies would be feasible. A biomarker of
aging would be a better predictor of life expectancy and future functionality than
chronological age. Unfortunately,
we even lack a method for biomarker validation. And if a biomarker could be validated
for rodents, how could we prove that the biomarker applied equally-well to humans? Without
biomarkers of aging we cannot say definitively if "accelerated aging" diseases
exist.
Without validated biomarkers of aging, it is difficult to prove that nutrients, drugs
or other interventions are slowing aging and extending the maximum lifespans of humans.
With biomarkers, it would only be necessary to show reduced deterioration within a
reasonable time-frame (a few years) in humans. Without biomarkers, positive proof of an
anti-aging intervention for humans could only come by observing effects on lifespan in
studies lasting decades or centuries. To be of use within our own lifetimes, the results
from short-lived mammals may be the best we can hope for if biomarkers are not found.
Despite years of effort, biogerontologists have not had much success in their search
for biomarkers of aging [[EXPERIMENTAL GERONTOLOGY; Johnson,TE; 41(12):1243-1246 (2006)](http://www.ncbi.nlm.nih.gov/pubmed/17071038)
and [BIOLOGICAL CHEMISTRY; Simm,A; 389(3):257-265 (2008)](http://www.reference-global.com/doi/abs/10.1515/BC.2008.034)].
Insofar as [Caloric Restriction with
Adequate Nutrition](../calories/calories.html) (CRAN) seems to slow aging in rodents and many other short-lived
species, long-term studies of CRAN on monkeys are being conducted to establish if CRAN also
slows aging in primates. Although it will take decades for these studies to run to
completion and current data is not yet statistically significant, rhesus monkeys on CRAN
show the same reductions of body temperature & plasma insulin as CRAN rodents, as well
as showing a slower decline in serum
[DeHydroEpiAndrosterone Sulfate](../nutrceut/DHEA.html)
(**DHEAS**). Men with
greater survival in the Baltimore Longitudinal Study of Aging also show reduced body
temperature & plasma insulin, along with elevated serum DHEAS — suggesting that
these three factors may be biomarkers of biological age [SCIENCE 297:811 (2002)].
Skin biopsies from CRAN & control nonhuman primates have been used to assess
glycation & **glycoxidation** (oxidation of glycation products to form AGEs).
**Furosine** as a measure of glycation increased mildly with age in the control
animals and this increase was significantly reduced in CRAN animals. Using
[pentosidine](http://en.wikipedia.org/wiki/Pentosidine) as a measure of glycoxidation, no significant variations were
observed — but results for tissues other than skin might have been different [JOURNALS
OF GERONOTOLOGY 58A(6):508-516 (2003)].
F2−isoprostanes are stable products of oxidized arachidonic acid
which can be readily measured in urine to quantify lipid peroxidation. Plasma
concentrations rise dramatically with age in rats, providing support for the
association of lipid peroxidation with aging and for the potential of F2−isoprostanes
as biomarkers of aging [BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
287:254-256 (2001)]. (For details on isoprostanes see
[Essential Fatty Acids in Cell
Membranes](../health/essfat.html#cell).)
A statistically significant trend (with extremely wide variation) of T−cell subsets in
mice provides a potential biomarker. Mice with low levels of CD4 & CD8 memory cells, high
levels of CD4 naive cells and low levels of P−glycoprotein CD4 cells live 6%
longer [JOURNALS OF GERONTOLOGY; Miller,RA; 56A(4):B180-B186 (2001)]. The "biomarker"
based on these four T−cell subsets was able to predict longevity of 18-month-old mice
with [P−values](http://www.sportsci.org/resource/stats/pvalues.html)
less than 0.003. Mice most often die of cancer, so this might be a
better indicator of mortality risk. But if valid, would this biomarker indicate that the immune
system theory of aging predominates, or would it indicate that the aging process simply impinges
most predictably on the immune system?
With aging the [sleeping EEG patterns](../health/sleep.html#eeg)
known as "sleep spindles" and "K−complexes" diminish in
number — and it has been suggested that this change can be used as a biomarker of
brain aging [CLINICAL NEUROPHYSIOLOGY; Crowley,K; 113(10):1615-1622 (2002)]. There
is also reduced circadian signaling with age, and much of this reduction may be
due to reduced [melatonin](../nutrceut/melatonin.html)
secretion [NEUROBIOLOGY OF AGING; Munch,M; 26(9):1307-1319 (2005)].
In the Framingham study (a longitudinal epidemiological study
of large size and long duration in Framingham, Massachusetts that has
focused on cardiovascular disease risk factors) lung volume (largest
volume of air that can be voluntarily expelled from the lung) — which
decreases with age in smokers & non-smokers —
was well correlated with risk of death in the 45−74 year-old age-range.
But even lung volume was inferior to chronological age as a predictor
of overall mortality risk. Forced expiratory volume in one second remains
the best predictor of all-cause
mortality [[CHEST; Schunemann,HJ; 118(3):656-664 (2000)](http://chestjournal.chestpubs.org/content/118/3/656.long) and
[EUROPEAN RESPIRATORY JOURNAL; Young,RP; 30(4):616-622 (2007)](http://erj.ersjournals.com/cgi/content/full/30/4/616)],
but that does not mean that it is a biomarker of aging.
If mortality risk were the definitive characteristic of aging, then standing in an
open field criss-crossed with machine-gun fire would be a biomarker of aging. If aging
is damage to organs, tissues, cells and macromolecules then many kinds of damage need
to be considered. Certain kinds of damage are more related to specific disease conditions
than generalized "aging". Damage to substantia nitra cells leads to
Parkinson's Disease, nuclear DNA mutations lead to cancer, glycation of lens crystallins
leads to cataracts, etc. Nonetheless, aging increases the predisposition to these
disease conditions.
Partly because of the failures to find biomarkers, some biogerontologists question that
a unitary process of aging exists — asserting that the phenomenon called "aging"
is really multiple degenerative processes operating in parallel. A unitary cause of aging
might necessitate discovery of a unitary biomarker. The multiple forms of damage to
macromolecules, cells and tissues associated with aging points to multiple causes, and
would necessitate multiple biomarkers. Despite the fact that
different mechanisms must be involved, the rather uniform slowing of aging seen for dwarf
mice and CRAN-diet (versus ad-libitum fed) animals would seem to validate the existence of a
unitary aging process — as does the comparison of aging rates between species or breeds
of dogs.
But aging can only be the result of damage to macromolecules: proteins, lipids, carbohydrates,
and DNA (including telomeres). Causes of aging damage are reactive oxygen & nitrogen species,
sugars (glycation), radiation, pathogens, inflammatory cytokines, and accumulated toxins
(metals, PCBs, dioxins, etc.). The different aging rates of different species is due to
the fact that endogenous damage is produced at different rates (eg, bird mitochondria produce
fewer free radicals than mammalian mitochondria), different protective mechanisms exist
(eg, naked mole rats arrest cancer growth with contact inhibition), and more long-lived
species more effectively eliminate damage (eg with better lysosome enzymes, better DNA repair,
better autophagy, etc.). If aging is programmed genetically, it can only be programmed to reduce
damage formation or remove/repair damage better or worse.
Exogenous agents can accelerate forms of aging damage. Diabetes and dietary
Advanced Glycation End-products (**AGEs**) accelerate protein
cross-linking [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Koschinsky,T;
94(12):6474-6479 (1997)](http://www.pnas.org/content/94/12/6474.long)]. Immunosenescence is substantially associated with
cytomegalovirus [[CURRENT OPINION IN LIPIDOLOGY; Derhovanessian,E; 21(4):440-445
(2009)]. White blood cell telomere attrition is accelerated in obesity and insulin
resistance [[CIRCULATION; Gardner,JP; 111(17):2171-2177 (2005)]. There is
considerable overlap in the histopathology of skin photoaging and skin intrinsic
aging [[EXPERIMENTAL DERMATOLOGY; El-Domyati,M; 11(5):398-405 (2002)].
A high fat meal elevates plasma inflammatory cytokines more than a high carbohydrate
meal [[JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY; Nappo,F; 39(7):1145-1150
(2002)], and plasma inflammatory cytokines are substantially associated with
age-related cataract [[AMERICAN JOURNAL OF OPTHALMOLOGY; Klein,BEK; 141(1):116-122 (2006)].
F2−isoprostanes (the best marker of lipid peroxidation) are
substantially elevated in the foam cells of atherosclerotic
plaque [[JOURNAL OF CLINICAL INVESTIGATION; Pratico,D; 100(8)2028-2034 (1997)],
and F2−isoprostanes in the urine of smokers drops by
more than one third after two weeks of smoking
cessation [[NEW ENGLAND JOURNAL OF MEDICINE; Morrow,JD; 332(18):1198-1203 (1995)].
Because aging is due to multiple forms of damage, there can be no
singular underlying biological age. Cause of death and impairment of
functionality will be a function of which form of damage is the
greatest — which will vary from person to person. Rather than
engage in a fruitless search for a biological age (biomarker of aging),
biogerontologists should seek assays for every possible form of aging
damage. Damage assays can allow for ranking forms of aging damage,
prioritizing interventions, and monitoring intervention effectiveness.
[(return to contents)](#contents)
### XXIV. CALORIC RESTRICTION WITH ADEQUATE NUTRITION (CRAN)
[Caloric Restriction with
Adequate Nutrition](../calories/calories.html) (CRAN) dramatically extends the maximum lifespan of laboratory animals.
Victims of starvation & malnutrition are not experiencing the life-extending
benefits of CRAN — ***adequate nutrition*** (vitamins, minerals, essential
amino acids and essential fatty acids in adequate quantity) is absolutely necessary
for calorie restricted diets to extend lifespan. Because almost every aspect of the
aging process appears to be slowed by CRAN, studying CRAN has become a means of
defining & understanding the aging process itself — including the search for
biomarkers of aging.
Rats, mice and hamsters experience maximum
lifespan extension from a diet which contains 40−60% of the calories (but all
of the required nutrients) which the animals consume when they can eat
as much as they want. Mean lifespan is increased up to 65% and maximum lifespan
is increased up to 50%, when CRAN is begun just before puberty. Except for the puberty
effect, it is as if all animals are allotted a lifetime supply of food — and those
who eat more slowly live longer because it takes longer to consume all the food.
The mechanism by which caloric restriction has such dramatic effects is
unproven, but maturity, thymus shrinkage, DNA-repair decline and tumor
formation is delayed. The experimental animals show more complete oxidation
of fatty acids, with fewer ketones (R'RC=O) in the blood, and cell membranes have less
cholesterol & saturated fatty acids. Collagen cross-linking occurs more
slowly in rats on CRAN which have blood glucose levels reduced about 15%
below controls. Reduction of visceral body fat is associated with reduced
[insulin resistance](../health/MacroNut.html#syndrome) due to
reduced levels of proinflammatory cytokines [EUROPEAN JOURNAL OF CLINICAL
INVESTIGATION 32(Suppl 3):24-34 (2002)].
Oxidative damage (8−oxodG) to mtDNA is 16 times greater than to nDNA in the livers of
6−month old rats [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Richter,C;
85(17):6465-6467 (1988)](http://www.pnas.org/cgi/content/abstract/85/17/6465)]. Although CRAN does not reduce oxidative damage (8−oxodG) to
rat liver nDNA and only reduces oxidative damage to mouse liver nDNA by 19%, it completely
eliminates mtDNA damage in both the rat &
mouse [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Hamilton,ML;
98(18):10469-10474 (2001)](http://www.pnas.org/cgi/content/full/98/18/10469)]. One year of CRAN in rats has been shown to reduce liver
mitochondrial hydrogen peroxide production from Complex I by 47% [FREE RADICAL
BIOLOGY & MEDICINE; Lopez-Torrez,M; 32(9):882-889 (2002)]. For mammalian species, a
negative exponential correlation has been demonstrated between liver mitochondrial hydrogen
peroxide production and maximum lifespan [JOURNAL OF COMPARATIVE PHYSIOLOGY B;
Perez-Campo,R; 168:149-158 (1998)].
Although CRAN animals produce fewer free radicals, their **metabolic rate**
(oxygen consumption per gram of tissue) is not reduced. The inner mitochondrial membranes
of CRAN animals have a higher saturated/unsaturated fat ratio making them less vulnerable
to proton leak from lipid peroxidation. Both [state 3 & state 4 respiration rates](./aging.html#mitochondria)
are greatly reduced in brain, heart & kidney tissue [THE INTERNATIONAL JOURNAL
OF BIOCHEMISTRY & CELL BIOLOGY 34:1340-1354 (2002)]. CRAN rats show 15% less plasma
glucose and 50% less plasma insulin than controls, having the same rate of glucose
utilization per unit mass, meaning that glucose is being more efficiently
utilized [JOURNAL OF GERONTOLOGY; Masoro,EJ; 47(6):B202-B208 (1992)].
Macroautophagy is normally induced during conditions of starvation. CRAN
in the nematode ***C. elegans*** induces macroautophagy, whereas
inhibiting the genes required for macroautophagy inhibits the genes require
for autophagy — and prevents CRAN from extending
lifespan [[PLOS GENETICS; Hansen,M; 4(2):e24 (2008)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242811/)].
A convincing case has been made that CRAN operates by
evolutionarily-conserved mechanisms of nutrient-sensing molecular
pathways (insulin/IGF-1) in yeast, worms, flies, and
mammals [[SCIENCE; Fontana,L; 328:321-326 (2010)](http://www.sciencemag.org/content/328/5976/321.full)]. CRAN does not
increase insulin sensitivity or extend the lifespan of Growth-Hormone Receptor
Knock-out mice, suggesting that insulin sensitivity plays a key role
in life extension by
CRAN [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Bonkowski,MS; 103(20):7901-7905 (2006)](http://www.pnas.org/content/103/20/7901.long)]. Exercise, however, increases
insulin sensitivity without increasing maximum
lifespan [[AGE; Fontana,L; 32(1):97-108 (2010)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829643/)].
Reduced body size within a species often correlates with longer lifespan
and reduced plasma IGF−1. Great Danes (400 ng/mL plasma
IGF−1) live about 7 years, whereas
Chihuahuas (40 ng/mL plasma IGF−1) can live over 15 years.
Insulin increases IGF-1 activity by lowering serum IGF-binding
protein [[JOURNAL OF BIOLOGICAL CHEMISTRY; Powell,DR;
266(28):18868-18876 (1991)](http://www.jbc.org/content/266/28/18868.long)].
Longevity in humans is correlated with a genetic predisposition
to low plasma IGF-1 [[JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM;
Bonafe,M; 88(7):3299-3304 (2003)](http://jcem.endojournals.org/content/88/7/3299.long)]. Rodents consistantly show reduced
plasma IGF-1 on CRAN, but for humans plasma IGF-1 is reduced by protein
restriction, not calorie
restriction [[AGING CELL; Fontana,L; 7(5):681-687 (2008)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673798/)].
An ongoing study of rhesus monkeys (which have a maximum lifespan of 40 years)
has shown a 50% reduction in cancer and cardiovascular disease for the animals
subjected to 30% calorie restriction compared to
controls [[SCIENCE; Colman,RJ; 325:201-204 (2009)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812811/)].
But the rhesus monkey studies are still in
progress [[SCIENCE; Roth,GS; 297:811 (2002)](http://www.sciencemag.org/content/297/5582/811.long)].
There is reasonable evidence that the benefits of CRAN seen in rodents apply to humans.
Contrary to former reports of a "J−shaped" relationship between body
weight and human mortality, when corrections are made for smoking and underlying
disease the relationship is linear [NEW ENGLAND JOURNAL OF MEDICINE; Manson,JE;
333(11):677-685 (1995)]. Of course, anorexics who are malnourished for micronutrients
are not examples of human CRAN. There may well simply be a continuum between
CRAN and the [metabolic syndrome](../health/MacroNut.html#syndrome), meaning the benefits of CRAN are
simply a matter of quantity of calories, versus the idea that CRAN is
some qualitatively distinct metabolic state.
Humans who have practiced CRAN for about six years show considerable
reduction in risk factors for atherosclerosis, including reduced
LDL-cholesterol, increased HDL-cholesterol, reduced serum triglycerides,
and reduces systolic and diastolic blood
pressure [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA);
Fontana,L; 101(17):6659-6663 (2004)](http://www.pnas.org/content/101/17/6659.long)]. It is also to be expected that
CRAN reductions of inflammatory cytokines and growth factors would result
in reduced cancer in humans, as has been seen in rodents and
monkeys [[TRENDS IN PHARMACOLOGICAL SCIENCES; Longo,VD; 31(2):89-98 (2010)](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829867/)].
Elderly human subjects
(60 years average age) restricting calories 30% for 3 months showed
a 20% increase in verbal memory
scores [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Witte,AV;
106(4):1255-1260 (2009)](http://www.pnas.org/content/106/4/1255.long)].
Substantial evidence indicates that as much as half of the
life-extension benefits of CRAN are due to restriction of the single amino acid
[methionine](http://en.wikipedia.org/wiki/Methionine).
The lifespan of ***Drosophila*** fruit flies can be extended by reducing
casein or methionine [[NATURE; Flatt,T; 462:989-990 (2009)](http://www.ncbi.nlm.nih.gov/pubmed/20033028)]. In a study of rats given
20% the dietary methionine of control rats, mean
lifespan increased 42% and maximum lifespan increased
44% [[THE FASEB JOURNAL;Richie,JP; 8(15):1302-1307
(1994)](http://www.fasebj.org/content/8/15/1302.long)]. A study of male rats subjected to methionine restriction,
but no restriction of calories, showed the same decreases in mitochondrial reactive oxygen
species and oxidative damage to DNA as was seen with rats subjected to
CRAN [[FASEB JOURNAL; Sanz,A; 20(8):1064-1073 (2006)](http://www.fasebj.org/cgi/content/full/20/8/1064)].
(See [Life Extension
Benefits of Methionine Restriction](../calories/Meth.html) for more details.)
Attempts have been made to find a pill that would mimic the effects of CRAN. Using
gene chips it has been found that [Metformin](http://en.wikipedia.org/wiki/Amygdala) results in the same gene expression seen in CRAN. (See
<http://www.lef.org/magazine/mag2003/2003_preprint_bio_01.html>
and <http://www.lef.org/magazine/mag2001/sep2001_report_metformin_01.html>.) But Metformin only
extends mouse lifespan a third as much as CRAN.
For technical details about CRAN — plus an account of my personal
experiences with CRAN — see my essays
[Caloric Restriction with Adequate Nutrition — Overview](../calories/cran95.html) ,
[My Practice of Caloric Restriction with Adequate Nutrition](../calories/cran98.html)
and [My Current Health Regimen — Exercise, Diet, Supplements](../personal/regimen.html).
[(return to contents)](#contents)
### XXV. OTHER METHODS TO SLOW AGING
As I stated in the beginning, my primary concern in this essay has been
to elucidate the ***mechanisms*** of aging, rather than
***methods*** to prevent it. But the ***goal***
of my understanding is indeed to apply
an understanding of mechanisms to the evaluation of methods. Literature
on methods to extend ***maximum*** lifespan which is strongly
grounded in scientific research is rare. The primary reason for this
scarcity is lack of funding for such research.
In contrast with ***maximum*** lifespan, there is a vast
amount of literature on ways to extend ***mean*** (average)
lifespan through diet & exercise and avoidance of dangers, toxins
& disease. Only 26% of smokers live to age 80, in contrast with
57% of nonsmokers [ADDICTION 97:15-28 (2002)]. A practical
life-extensionist currently has far more to gain by utilizing
information available on extending mean lifespan than by preoccupation
with maximum lifespan. Some misguided life-extensionists have discounted
the use of anti-oxidant supplements because they have only been shown
to be of benefit in extending mean lifespan, not maximum lifespan.
A prime candidate for a biomarker
of aging (which has been a focus of attention in the calorie restriction with
adequate nutrition studies of primates) has been
[insulin resistance](../health/MacroNut.html#syndrome).
Reduced glycation may be achieved by reduction of typical blood glucose
levels. Low fat meals are one means to achieve this because fatty acids
promote insulin resistance — and greater insulin resistance means that
higher blood glucose levels are required to supply cells with the same
amount of glucose (causing more glycation) [THE NEW ENGLAND JOURNAL OF
MEDICINE 342(19):1440-1441 (2000) and DIABETES CARE 20(11):1774-1780 (1997)].
(Insulin resistance is a fundamental cause of adult-onset diabetes.) Also,
increased consumption of soluble fiber (particularly the beta-glucan found
in oat bran & barley) lowers 24−hour plasma glucose & insulin
concentrations. Experiments demonstrating that lysine-glycation predicts early
death in both CRAN & freely-fed rats makes lysine-glycation a very promising
biomarker candidate [FASEB JOURNAL 14:145-156 (2000)]. (For more on these
subjects see
[the metabolic
syndrome](../health/MacroNut.html#syndrome))
Although no substance has
been shown conclusively to extend maximum lifespan in humans, a few studies
indicate that some supplements may extend the lives of laboratory mammals
(mice, rats or guinea pigs, usually). The are quite a few studies indicating
that [Deprenyl](../lifeext/deprenyl.html), for example,
has extended the maximum lifespan of a variety of mammals.
There is at least one book (self-published), which is based on a serious
attempt to search the scientific literature for methods to extend
maximum lifespan.
Dr. Thomas Donaldson has reviewed those supplements that appear to extend
the lifespan of mammals in at least one scientific study
in his self-published book A GUIDE TO ANTI-AGING DRUGS. It
would be more accurately titled A GUIDE TO ANTI-AGING SUPPLEMENTS because,
although Procaine, Deanol,
[Deprenyl](../lifeext/deprenyl.html),
Levodopa, Phenformin and Phenytoin
deserve to be called drugs, Vitamin E, Pyridoxine, Pantothenate, Melatonin,
Cysteine, Chromium and Coenzyme Q10 do not. Five mechanisms are identified
by which these supplements work:
(1) anti-oxidation
(2) anti-glycation
(3) affecting metabolism
(4) improving the immune system
(5) acting on the brain.
Dr. Donaldson died early in 2006 and his self-published book
may be difficult to obtain.
Although Hormone Replacement Therapy (HRT) to bring androgens, estrogens and
growth hormone to youthful levels improve cognitive function & muscle tone (among other
benefits) these hormones promote cancer growth and therefore may be dangerous to use until
cancer is preventable & curable. By contrast,
[DHEA](../nutrceut/DHEA.html) not only protects against obesity,
diabetes & autoimmune disease, it reduces cancerous tumor-formation [ADVANCES
IN ENZYME REGULATION 26:355-382 (1987)] and can protect against excitotoxic damage in
the hippocampus [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA) 95(4):1852-1857
(1998)](http://www.pnas.org/cgi/content/full/95/4/1852)].
The [nutraceuticals section of my website](../nutrceut/nutrceut.html) describes a number of supplements
which may extend average, if not maximum, lifespan.
[Life
Extension Magazine](http://www.lef.org/magazine/mag_all.html) — which is available at no cost online — regularly
publishes articles with many fine citations to research on nutraceuticals
(primarily animal studies) which could potentially be of great benefit in
extending human life.
Cardiovascular function declines and insulin resistance increases
with age for most people. But most of these changes can actually be
attributed to declining physical activity and increasing abdominal
obesity associated with aging — rather than senescence ***per
se***. Higher HDL-cholesterol, lower triglycerides, lower
insulin-resistance & prevalence of diabetes, good cerebral
perfusion, good glucose metabolism, good
cardiovascular function and good endocrine function of older people
who engage in regular vigorous aerobic exercise are nearly to the
level of that seen in their younger counterparts — in sharp
contrast to their sedentary peers [NEW ENGLAND JOURNAL OF MEDICINE
328:533-537 (993); AMERICAN JOURNAL OF PHYSIOLOGY 268:E484-E490
(1995); JOURNAL OF THE AMERICAN GERIATRIC SOCIETY 38:123-128 (1990)].
Health problems caused by sedentary living are too often blamed on
senescence.
Exercise is well-known to lower blood pressure and otherwise improve
cardiovascular health. And, as has been mentioned, exercise can boost
rejuvenating Growth Hormone (GH) more effectively than injections.
Exercise also normalizes other hormone responses to youthful levels
[JOURNALS OF GERONTOLOGY:BIOLOGICAL SCIENCE 51A(1):B30-B37 (1996)] and
reduces insulin resistance [METABOLISM 44(10):1259-1263 (1995)] while improving immune
function [MECHANISMS OF AGING AND DEVELOPMENT 93:215-222 (1997)].
Although excessively strenuous exercise can generate harmful levels of free
radicals, regular endurance exercise protects against free radicals by increasing
muscle levels of SuperOxide Dismutase (SOD), glutathione peroxidase
and reduced glutathione (GSH) (but has no effect on catalase)
[MEDICINE & SCIENCE IN SPORTS & EXERCISE 31(7):987-997 (1999)].
Vitamin E is particularly protective against exercise-induced
free radicals [AMERICAN JOURNAL OF PHYSIOLOGY 264:R992-R998 (1993)].
Vitamin E has a pro-oxidant potential that can only be prevented
by agents like Vitamin C and CoEnzyme Q10, which eliminate the
**alpha-Toc.** radical [ARTERIOSCLEROSIS, THROMBOSIS
AND VASCULAR BIOLOGY 16:687-696 (1996)]. (For more on exercise, see
[Exercise](./longgene.html#exercise))
According to the Honolulu Heart Program, the best predictors of "successful
aging" were low blood pressure, low blood sugar, abstinence from tobacco and
not being obese. The Framingham study concluded that
by holding 11 different risk factors (such as blood pressure & serum
cholesterol) at the 30-year-old level, women would live to be 97 and
men would live to age 100. As the above review should indicate, many of
the afflictions of aging (including vascular dementia) are the result of
poor cardiovascular health. Therefore, despite the fact that maximum
lifespan is not extended, the effects of extended youth & extended health
would nonetheless be expected from measures extending average lifespan —
cardiovascular health, in particular. Atherosclerosis not only increases
blood pressure and the risk of death from stroke & heart attack, but
reduces the health & function of all organs (including the brain)
through impaired circulation.
It is difficult to
gain much immediate benefit from insights into molecular mechanisms of
aging, but enormous immediate benefit can be gained from reducing
calorie intake (while maintaining adequate nutrition), avoiding tobacco,
avoiding [alcohol](../health/alcohol.html),
exercising, taking supplements, eating low-fat/high-fiber diets, etc.
Epidemiological evidence indicates that adherence to a vegetarian diet for more
than two decades can increase lifespan 3.6 years [AMERICAN JOURNAL
OF CLINICAL NUTRITION 78(Suppl):526S-532S (2003)].
And [cryonics](../cryonics/CryoFAQ.html) may serve
as "first-aid" to transport us to the time when significant
advances in the elimination of senescence have occurred.
Some geronotologists believe that somatic gene therapy
can accomplish such goals as removing the telomerase gene from somatic cells (to reduce
cancer), migrating mitochondrial DNA into the nucleus and utilizing bird mitochondria genes
to create modified human mitochondria which produce fewer free radicals. With
"adequate funding" these gerontologists believe an ageless
mouse can be created within a decade
([The Methuselah Mouse Prize](http://www.methuselahmouse.org/)).
Every year we can add to our lives now increases our chances of
living to the time when technology can eliminate & reverse aging — or
cryonics can induce perfect suspended animation.
This essay is not the place to summarize every practice that can
possibly extend life or delay/avert death. See the pages on this
website dealing with
[Health](../health/health.html),
[Nutraceuticals](../nutrceut/nutrceut.html),
[Life-Extension](../lifeext/lifeext.html),
[CRAN](../calories/calories.html),
[Cryonics](../cryonics/cryonics.html),
[Death by Murder](./murder.html), and my
[statistical summary of all causes of death](./causes.html) .
[(return to contents)](#contents)
### XXVI. REGENERATIVE MEDICINE, STEM CELLS AND REJUVENATION
A healthy lifestyle, [CRAN](../calories/calories.html),
and perhaps even supplements can do no more than slow the aging process or
extend mean lifespan. Enduring youth might be attained if aging could be stopped
at a youthful age, but it seems unlikely that the damage to organs, tissues, cells
and molecules known as ***aging*** can be stopped completely. Replacing or repairing
damaged organs, tissues, cells and even molecules seems like a better strategy. These
strategies can restore function to old organisms — can even ***rejuvenate***.
Replacement of old or defective organs is a regenerative technique which has been
tantalizingly close for decades. Only a small fraction of potential candidates for
heart, kidney or liver transplants are able to benefit, because of low availability
and immune incompatibility. The development of a completely mechanical heart remains
out of reach, but there is hope that **ventricular assist devices** supporting the
left ventricle could benefit most end-stage heart-disease patients. Pigs have many organs
whose size is compatible for human transplant, but immune compatability and the threat
of viral infection remain obstacles.
Although the liver can mostly regenerate lost tissue, wounds to most
body tissues (including myocardial infarction) result in scar formation
rather than regeneration of functional tissue. Stem cells could allow
for true tissue regeneration. Human
[Embryonic Stem Cells](http://en.wikipedia.org/wiki/Embryonic_stem_cell) (**ESC**) have the
greatest potential to differentiate into any desired tissue type.
[Retrovirus](http://en.wikipedia.org/wiki/Retrovirus)
induction of overexpression of certain proteins can generate
[induced Pluripotent Stem Cells](http://en.wikipedia.org/wiki/Induced_pluripotent_stem_cell) (**iPSC**)
from fibroblasts. iPSC are nearly as pluripotent as ESCs. But both
ESCs and iPSCs can form
[teratomas](http://en.wikipedia.org/wiki/Teratoma)
(benign tumors) and induce antigenic tissue rejection (although iPSCs
are less antigenic than ESCs). Antigenicity can be reduced or eliminated
by regenerating the
[thymus
gland](http://en.wikipedia.org/wiki/Thymus) [[NATURE; Chidgey,AP; 453:330 (2008)](http://www.ncbi.nlm.nih.gov/pubmed/18480814)], by such
means as androgen
blockage> [[THE JOURNAL OF IMMUNOLOGY; Sutherland,JS; 175(4):2741-2753 (2005)](http://www.jimmunol.org/cgi/content/full/175/4/2741)].
When available, adult stem cells from the target tissue of the afflicted
patient are ideal for avoiding an antigenic response. But too often (as in
cases of tissue degeneration) such stem cells are not available. Stem cells
from the
[umbilical cord](http://en.wikipedia.org/wiki/Cord_blood)
cryogenically stored at birth have the potential for tissue regeneration
later in life.
Most attempts at genetic repair have traditionally involved the use of a retrovirus
to insert a new gene into a random position on a chromosome. But by attaching
[zinc fingers](../nutrceut/MiscSupp.html#zinc) (which determine
where transcription factors bind) to endonucleases (which break DNA strands) homologous
recombination can be induced to correct and replace defective (or undesired) DNA
sequence. The first applications of this technology are to isolate stem cells from
the bone marrow of patients having blood disease mutations, to correct those
mutations in lab dishes using zinc finger nucleases and to transplant the stem cells
back into the patients [SCIENCE; 310:1894-1896 (2005)].
Regenerative medicine looks for means to mimic salamanders (which can regrow
severed limbs), newts (which can regrow not only limbs, but intestine, jaw and spine)
and zebrafish (which can regrow a heart) — by replacing the dead scar tissue after
a heart attack with new heart cells.
Regenerative medicine uses three different strategies: (1) implantation
of stem cells from culture into an existing tissue structure (2) implantation of
stem cells into a tissue scaffold that guides restoration or (3) induction of
residual cells of a tissue structure to regenerate the necessary body part. A
salamander can not only regenerate a limb, but can regenerate the lens or retina
of an eye and can regenerate an intestine. For regeneration the salamander tissues
form a **blastema** by dedifferentiation of mesenchymal cells, and the blastema
functions as a self-organizing system to regenerate the
limb [SCIENCE; 310:1919-1923 (2005)]. [DNA microarray](http://en.wikipedia.org/wiki/DNA_microarray) analysis of salamanders has shown that humoral immune
and local tissue factors control the initial phase of limb regeneration, but nerve-derived
factors later become crucial [[BMC BIOLOGY; Monaghan,JR; 7:1-19 (2009)](http://www.biomedcentral.com/1741-7007/7/1)].
The MRL mouse, unlike other mice, can regenerate
damaged heart muscle without scar
formation [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Leferovich,JM;
98(17):9830-9835 (2001)](http://www.pnas.org/cgi/content/full/98/17/9830)]. Regenerative medicine would also aim to replace substantia
nigra cells in Parkinson's Disease and regrow a spinal cord after spinal cord injury.
Multipotent adult progenitor cells, such as bone marrow cells, have been shown to be
capable of replacing myocardial tissue destroyed by ischemic heart
disease [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA); Orlic,D;
98(18):10344-10349 (2001)](http://www.pnas.org/cgi/content/full/98/18/10344)].
Senescent cytotoxic T-cells have been removed from the serum of mice by
attachment of iron oxide nanoparticles linked to antibodies and applying
a magnetic field to the serum in an extracorporeal circuit [REJUVENATION
RESEARCH; Rebo,J; 13(2-3):298-300 (2010)].
Injured skeletal muscle has the capacity to regenerate in young mammals, but this
capacity is considerably impaired with aging. Activation & proliferation of muscle
regenerating progenitor cells (satellite cells) is dependent upon signalling from
transmembrane **Notch** receptors. Notch receptors have several **ligands**, ie,
extracellular molecules that the receptor requires to function. Upregulation of the
Notch ligand **Delta** has been shown to be sufficient to restore the regenerative
potential of skeletal muscle in old mice [SCIENCE; Conboy,IM; 302:1575-1577 (2003)],
Caution is advised in upregulating Notch, because overexpression of Notch can lead to
cancer [[BREAST CANCER RESEARCH; Dontu,G; 6:R605-R615 (2004)](http://breast-cancer-research.com/content/6/6/R605)]. The blood
plasma of young mice have been reported to restore the regenerative potential of both
muscle and liver cells in old mice [NATURE; Conboy,IM; 433:760-764 (2005)]. High
levels of **TGF−ß** (Transforming Growth Factor beta) in the blood of old mice
appears to be the problem. Systemic (serum) TGF−ß is
immunosuppressive [[THE JOURNAL OF EXPERIMENTAL MEDICINE; Wahl,SM; 180(5):1587-1590 (1994)](http://www.jem.org/cgi/reprint/180/5/1587)]
and aged cells have been shown to produce increased levels of
TGF−ß [IMMUNOLOGY LETTERS; Zhou,D; 36(1):7-12 (1993)]. Muscle regeneration
normally makes use of inflammatory
processes [[AMERICAN JOURNAL OF PHYSIOLOGY; Tidball,JG; 288(2):R345-R353 (2005)](http://ajpregu.physiology.org/cgi/content/full/288/2/R345)]
and TGF−ß has been shown to inhibit muscle
regeneration [[CIRCULATION RESEARCH; Zhu,S; 94(5):617-625 (2004)](http://circres.ahajournals.org/cgi/content/full/94/5/617)].
Organ transplant or even tissue transplant would not be of much benefit for an
aging brain, which is composed of non-dividing, enduring cells (neurons) whose
continued existence is crucial for the retention of knowledge and identity. In this case,
rejuvenation could be done on a molecular level rather than at the tissue or organ level.
For example, Aubrey de Grey has suggested that genes taken from bacteria could be
transmitted into the genome of human neurons to produce enzymes that dissolve &
eliminate lipofuscin, thereby rejuvenating the neuron. The same gene in blood vessel
"foam cells" could reverse atherosclerosis. There is evidence that the
extracellular protein cross-linking due to glycation which
leads to arterial wall stiffening as well as stiffening of the left ventricle can be
reversed by the thiazolium derivative ALT−711, which catalytically breaks
cross-links [[PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA)
97(6):2809-2813 (2000)](http://www.pnas.org/cgi/content/full/97/6/2809) and
[CIRCULATION; 104(13):1464-1470 (2001)](http://circ.ahajournals.org/cgi/content/full/104/13/1464)].
Biogerontologist Aubrey de Grey believes that reversing
aging may actually be more feasible than slowing aging, in the same sense that is sometimes
more economical to periodically repair damage than to go to extraordinary expense to
slow the rate of damage. Dr. de Grey believes that the key to rejuvenation is the
repair of seven distinct kinds of damage that represent aging: cell loss, cell senescence,
extracellular protein cross-linking, nuclear DNA mutations, mitochondrial DNA mutations
and the accumulation of garbage inside cells as well as outside cells. He has characterized
the repair of these seven kinds of damage as
[**Strategies for Engineered Negligible Senescence**](http://en.wikipedia.org/wiki/Strategies_for_Engineered_Negligible_Senescence) (**SENS**).
The seven repair strategies that Dr. de Grey advocates can
be summarized: (1) Cell loss can be repaired (reversed) just by suitable exercise
in the case of muscle, but for other tissues it needs various
growth factors to stimulate cell division, or in some cases it
needs stem cells. (2) Senescent cells
can be removed by activating the immune system against them. Or
they can be destroyed by gene therapy to introduce "suicide genes"
that only kill senescent cells. (3) Protein cross-linking can
largely be reversed by drugs that break the links. But for some of the
links we may need to develop enzymatic methods. (4) Extracellular
garbage can be eliminated by vaccination that gets immune cells
to "eat" the garbage. (5) For intracellular junk we need to
introduce new enzymes, possibly enzymes from soil bacteria, that
can degrade the junk that our own natural enzymes cannot degrade.
(6) For mitochondrial mutations the plan is not to repair them but
to prevent harm from the mutations by putting suitably modified copies of
the mitochondrial genes into the nucleus by gene therapy. The
mitochondrial DNA experiences so much mutation damage because
most free radicals are generated in the mitochondria. If
mitochondrial DNA can be moved into the nucleus it will be
better protected from free radicals, and there will be better
DNA repair when damage occurs. All mitochondrial proteins would
then be imported into the mitochondria. (7) For cancer (the
most lethal consequence of mutations) the strategy is to use gene
therapy to delete the genes for telomerase and to eliminate
telomerase-independent mechanisms of turning normal cells into
"immortal" cancer cells. To compensate for the loss of telomerase
in stem cells we would introduce new stem cells every decade or so.
For more background on Dr. de Grey's approach, see
[SENS Overview](http://www.gen.cam.ac.uk/sens/just7.htm).
The ultimate rejuvenation, however, will occur further in the future with the advent
of molecular repair technology (nanotechnology) which can fix ***all*** kinds of
molecular damage due to aging (as detailed in the book
[ENGINES OF CREATION](http://www.foresight.org/EOC/index.html) by [K. Eric Drexler](http://www.foresight.org/FI/Drexler.html)).
[(return to contents)](#contents)
### XXVII. AGING: CAUSE & CURE — SUMMARY & CONCLUSIONS
What causes aging? In other words, what lies behind the progressive deterioration that
accompanies the passage of time after maturity — with special interest to humans. To
answer in outline form:
#### * METABOLIC DAMAGE
##### + FREE RADICALS
##### + GLYCATION
#### * CELLULAR SENESCENCE & DEATH
##### + TELOMERE SHORTENING
##### + DECLINING & INADEQUATE DNA REPAIR & AUTOPHAGY
##### + DECLINING & INADEQUATE ANTI-OXIDANT DEFENSE
##### + DEFECTIVE CELL CYCLE CONTROL, PROTEASOMES, LYSOSOMES & HEAT SHOCK PROTEINS
#### * TOXIC & NON-TOXIC GARBAGE ACCUMULATION
##### + PROTEIN CROSS-LINKING & AGGREGATION
##### + ADVANCED GLYCATION END-PRODUCTS (AGEs)
##### + ATHEROSCLEROTIC AND AMYLOID PLAQUES
##### + INFLAMMATORY CYTOKINES
##### + LIPOFUSCIN
##### + CORTISOL
##### + METALS
##### + DDT, PCBs, etc
An organism that can create fewer free-radicals in generating energy (more efficient
mitochondria), use less energy to live, have more effective antioxidant defenses, have
better DNA protection, have better DNA repair, have a better immune system and detoxify
more effectively in the liver — can reduce damage from endogenous & exogenous sources.
Glucose is necessary for energy production, but glucose causes glycation of proteins.
Energy creation results in free radicals as a toxic byproduct. Toxic & non-toxic
garbage accumulation is primarily a problem for non-dividing cells (like neurons &
muscle cells) which cannot dilute-away the garbage. The damage which causes
aging is the damage due to necessary metabolism. This damage affects DNA repair, antioxidant
production, telomere length, cell-cycle control, proteosome function, etc. — resulting in
reduced capacity to cope with increasing levels of damage.
Telomere shortening contributes to mortality only in a few tissues. Neurons & muscle
cells are non-dividing and are thus not affected by telomere shortening. Telomere
shortening may contribute to mortality most significantly for immune system cells
& arterial epithelial cells. Even if telomere shortening in the immune system is proven
to cause the majority of deaths in the very elderly, the mortality is better described as
"failure of the weakest link" (like the death of wild horses from worn-down
teeth) than as ***aging***. If biological gerontologists are successful in finding
means to greatly increase human lifespan, then telomere shortening in proliferative
tissues may become far more relevant to human aging. (For non-dividing cells, notably
neurons, metabolic damage & garbage accumulation could be considered the "weakest
link" if it weren't for the fact that cell death is so different from cell
senescence.)
Metabolic damage would be much less of a problem if its byproducts (cross-links, AGEs,
lipofuscin, etc.) could be eliminated — along with whatever toxins (lead, cadmium, DDT,
PCBs, etc.) manage to enter the organism. The so-called immortality of germ cells, bacteria
and ***Hydra*** [EXPERIMENTAL GERONTOLOGY 33(3):217-225 (1998)] is probably due to
the diluting-away of toxins (all of the ***Hydra*** cells are dividing cells).
Lobsters — which have been proposed as candidates for negligible senescence
— discard tissue by molting and appear to continue growing without ever maturing. Lobsters
express telomerase in all organ tissues and may avoid senescence by the same mechanism as
***Hydra*** [FEBS LETTERS; Klapper,W; 439(1-2):143-146 (1998)].
Why does CRAN ([Caloric Restriction with
Adequate Nutrition](../calories/calories.html)) extend lifespan? The most plausible explanation is that the lower
level of calorie utilization & energy production allows for lower levels of blood glucose
(less glycation) and less free radical production. Efforts to duplicate CRAN with a pill
or genetic manipulation probably have no chance of success.
If the "accelerated aging" diseases
are a guide, damage to DNA — mitochondrial (mtDNA) and nuclear (nDNA) — are the
damage that is most central to aging. Damage to nDNA and nDNA repair capability
would be the worst because mitochondria (and mtDNA) can be replaced by lysosome
recycling. But the source of that nDNA damage would still be mitochondria.
Defective nDNA repair along with associated cell senescence & apoptosis leads
more to aging, whereas the nDNA damage itself leads
more to cancer. For mtDNA damage, the damage becomes most serious when the lysosomes are
no longer capable of removing defective mitochondria which are producing high levels of
free radicals. Free radicals are the primary cause of the nDNA and mtDNA damage in the
first place. Defective mitochondria play a central role in accelerated apoptosis, leading
to tissue degradation. If defective mitochondria which produce high levels of free radicals
are the major source of aging damage, then the most effective step towards slowing aging
would be improving lysosomal function by providing more efficient enzymes to the lysosomes.
The maximum lifespan of one or a few individuals of a species is taken as a proxy for
the rate of aging of that species and for the idea that only extensions of maximum
lifespan are relevant to slow aging. But most people die of aging-related diseases:
cardiovascular disease, cancer, Alzheimer's Disease, etc. The damaging aging processes
that increase vulnerability to these diseases are more relevant to vast majority of
people than influences on maximum lifespan. For this reason it is not misleading to
speak of diabetes, tobacco, dietary AGEs, ultraviolet radiation and other exogenous
sources of tissue damage as accelerating aging — especially when the damage so
closely resembles the tissue damage normally associated with aging. For the vast
majority of people good genes can only reduce (not prevent) the aging effects of
damaging exogenous agents. (For more on this subject, see [Is Longevity Entirely Hereditary?](./longgene.html))
The "mechanisms of aging" tend to be quite tissue-specific. Replicative
senescence leads to aging of T cells and blood vessel endothelial cells, whereas
other forms of cell senescence leads to aging of stem cells in the pancreas and
selected areas of the brain. Non-mitotic cells such as neurons and myocytes are
more vulnerable to oxidative stress and DNA damage. Glycation leads to cross-linking
of extracellular proteins. For any particular individual, the combination of
heredity and environmental conditions will cause some tissues and organ systems
to age (or experience damage) more than others — and becoming the "weakest
link" leading to mortality. The number or individuals who do not succumb to
age-related death specific to a particular tissue or organ is a tiny minority.
Until molecular repair technologies are available, good health practices,
supplements and organ transplantation are our best hope of bridging
the time between now and the Age of Negligible Senescence.
To see what the elimination of aging would mean to me personally, read
my essay [Why Life Extension?](../lifeext/whylife.html)
[(return to contents)](#contents)
### XXVIII. BOOK REFERENCES (by publication date)
(references to scientific papers are incorporated in the text)
* AGING OF THE GENOMOE Jan Vijg 2007
* AGING OF ORGANS AND SYSTEMS Richard Aspinall (Editor) 2003
* AGING OF ORGANISMS Heinz Osiewacz (Editor) 2003
* MODULATION OF AGING AND LONGEVITY Surish Rattan (Editor) 2003
* AGING OF CELLS IN AND OUTSIDE THE BODY S.Kaul/R.Wadhwa (Editors) 2003
* AGING AT THE MOLECULAR LEVEL Thomas von Zglinicki (Editor) 2003
* AGELESS QUEST Leonard Guarente 2003
* ANNUAL REVIEW OF GERONTOLOGY AND GERIATRICS (V.21) V.Cristofalo 2001
* HANDBOOK OF THE BIOLOGY OF AGING E.Masoro/S.Austad (Editors) 2001
* THE MITOCHONDRIAL FREE RADICAL THEORY OF AGING Aubrey de Grey 1999
* BIOLOGY OF AGING (2nd Ed.) Robert Arking 1998
* IMMORTALITY Ben Bova 1998
* WHY WE AGE Steven N. Austad 1997
* PRINCIPLES OF NEURAL AGING S.Dani,A.Hori & G.Walter 1997
* HANDBOOK OF THE BIOLOGY OF AGING E.Schneider/J.Rowe (Editors) 1996
* CELLULAR AGING AND CELL DEATH Holbrook,Martin,Lockshin (Editors) 1996
* CHEATING TIME Roger Gosden 1996
* REVERSING HUMAN AGING Michael Fossel 1996
* THE CLOCK OF AGES by John Medina 1996
* UNDERSTANDING AGEING Robin Holliday 1995
* THE MOLECULAR BASIS OF AGING Alvaro Macieira-Coelho (Editor) 1995
* GENES AND AGING M.S.Kanungo 1994
* HOW AND WHY WE AGE Leonard Hayflick 1994
* FREE RADICALS IN AGING B.P. Yu (Editor) 1993
* LIFESPAN Thomas J. Moore 1993
* STRESS, THE AGING BRAIN, AND THE MECHANISMS OF NEURON DEATH Robert Sapolsky 1992
* LIFE SPAN PROLONGATION V. Frolkis & K. Muradian 1991
* AGING, SEX AND DNA REPAIR Carol & Harris Bernstein 1991
* LONGEVITY, SENESCENCE AND THE GENOME Caleb E. Finch 1990
* LIPOFUSCIN AND CEROID PIGMENTS Edwardo Porta (Editor) 1989/1990
* BEYOND THE HELIX Carol Kahn 1985
* MAXIMUM LIFESPAN Roy Walford 1983
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<a href="igy1/1957.html"><img src="igy1/1957inside2.jpg" width=219 height=135 border=0 alt="this place is going to the dogs already" title="this place is going to the dogs already" align=left></a>
<a href="77march.html"><img src="../pole/door212.jpg" width=250 height=135 alt="1977 winterovers" title="the dome is home" align=right></a>
<div align=center><h1><font face="Arial,Helvetica">Winterover Statistics</font></h1></div>
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<p>1702 people have wintered over at least once at the South Pole from 1957 through 2023. Since some of these folks wintered more than once, there actually have been a total of 2124 winterover positions. And if you haven't found the winterover lists yet, they are included, along with photos and other information as available, in the <a href="trivia.html">timeline entries</a> for each year through 2022 at this point. Actually I should also say that there is a complete database spreadsheet, with winterover numbers, updated to date, on this web site, slightly hidden to protect the list of names from spammers. Access is available to Polies upon request. Although it is obvious that I've made errors and omissions in the past, I'm pretty confident that the basic list of folks is complete and accurate, if only because it has been more than 16 years since someone wrote me claiming I'd left someone out :) Suggestions/corrections...<a href="../info.html">please let me know!</a></p>
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<div align=center><a href="06_winterover_lineup1.jpg"><img src="06_winterover_lineup2.jpg" width=600 height=400 alt="Photos of South Pole winterovers in the A3 second floor hallway" title="a gallery of rogues"></a></div></td><td width=360><p>At left, a view of the main second floor hallway and the gallery of winterover pictures dating from 2012 back to the first winter in 1957...most of these were hung, edited and/or reframed by Andy Martinez and Terry Eddington during the 2007 winter <a href="http://antarcticsun.usap.gov/features/contentHandler.cfm?id=1208">(<i>Antarctic Sun</i> article)</a>. Some of the frames were fabricated with wood from the old Dome sauna or gym floor. We are still missing a few pictures...1960, 1962, 1963, and 1968 from the Navy days and 1976, 1979, and 1986 from the dome era--you know who you are :). This photo by 2012 <span style="color: blue;" title="South Pole Telescope">SPT</span> winterover <!-- <a href="http://www.physicschick.com/pole/index.html"> --> <a href="http://www.physicschick.com">Cynthia Chiang</a> shows those <a href="10s/2011.html">2011</a> and <a href="10s/2012.html">2012</a> photos that include the members of Amundsen's and Scott's parties.</p>
<p>As the north wall of the hallway is now filled with photos, the more recent winterover photos are being hung on the south wall.</p>
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<p>In 2023 there are 43 <a href="npx.html">NPX</a> winterovers...about average since construction completion of the elevated station, and the group includes 6 women and 37 men. In 1998-99, when construction began on the first phase of the new station (the fuel arch in the summer and the heavy shop in summer/winter)...there were 41 winterovers...before that there were never more than 28 winterovers. The largest crowd ever was my 2005 winter when we had 86 folks, including 24 women! In the old days, the first three years with women (1979-81) the crews included only one woman--in hindsight that experiment was probably not the best idea.</p>
<p>Seven of the 2023 winterovers have previously wintered at least once...a drop from 2022 when there were 12 repeaters among the 44 winterovers. The 2023 people with multiple winters include food services supervisor Zeke Mills and Jonathon Weise with 3 winters, as well as satcom engineer Ryan Gutierrez, power plant lead mechanic Seva Kotlyar, supply tech Tammy McDermott, <span style="color: blue;" title="South Pole Telescope">SPT</span> grantee Cal Neske, and network engineer Christian Rahl with 2 winters.</p>
<p>2023 winterover nationalities...there are three new countries represented this year--IceCube observer Hrvoje Dujmovic is from Croatia, heavy equipment operator Federico Piola is from Argentina, and Naweed Hashimi is of Afghan heritage. Power plant mechanic Seva Kotyar from Russia has returned for his second winter in a row, and IceCube grantee Marc Jacquart is the second winterover from Switzerland...the first was 2003 maintenance scheduler Monique Gerbex who was born in Switzerland and later lived in Vermont. Supply technician Jaden Pan was born and raised in Toronto. And...Michelle Endo is the first woman winterover with Japanese heritage...there have now been five Japanese winterovers <a href="japan.html">(list)</a>.</p>
<p>2022 international stuff...both IceCube winterovers Mareno Baricevic (from Italy) and Celas Marie-Sainte (from France) have previously wintered at the Italian/French station Concordia located at Dome C...a bit higher up than Pole at 10,607 feet/3,233 meters altitude.</p>
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<table width=1100>
<tr><td width=550><div align=center><a href="2022marker.html"><img src="newnight2.jpg" width=400 height=324 alt="winter side of the marker" title="look to the north"></a></div></td>
<td width=550><div align=center><a href="2022marker.html"><img src="newday2.jpg" width=400 height=329 alt="summer side of the marker" title="I tell none but sunny hours"></a></div></td></tr></table>
Above...both the winter and summer sides of the marker that was revealed to the world on 1 January 2023. It was fabricated by<br>winterover Thomas Leps...who actually didn't get it 100 % finished until just before he left in late January. <a href="2022marker.html">Details and photos!</a></div>
<p>In the 2020 winter there was a new record regarding the winter site manager position. Previously 3 people have held that job twice--Bill Henriksen in 2003 and 2005, Katie Hess in 2008 and 2012, and Wayne White in 2017 and 2019. But for 2020 Wayne has returned for his third time as manager...and in two consecutive years (he did take some time away during the summer). Bill and Katie each wintered 3 times, but their first winters were in other positions.</p>
<div align=center><a href="2021marker.html"><img src="2022marker2.jpg" width=500 height=333 alt="the 2022 Pole marker" title="all signs point north"></a><br>
Above, the 2022 Pole marker unveiled on New Years Day...designed by BICEP Array winterover Brandon<br>Amat and amazingly fabricated by Dave Pernic...not his first marker fabrication! <a href="2021marker.html">More information!</a></div>
<p>During the Dome era, many of the managers had previously wintered in another position--the first of these being Tom Plyler who was the power plant mechanic in 1975 and manager in 1981. Now, three managers to date have subsequently returned to winter again in another position: Don McCreight was the manager in 1997--he returned in 2015 to winter as carpenter foreman (and has been back for some other summers as well). Gary Freeman was manager in 1992 and returned as <span style="color: blue;" title="safety/environmental/health">SEH</span> coordinator in 1995. And Bill Spindler, who was manager in 1977, returned to winter in 2005 as Title II inspector and in 2008 as a project engineer--with a gap of 28 years between his 1977 and 2005 winters. That is not an overall Antarctic record; Australian Brian Jury wintered at Mawson in 2017, 31 years before that he wintered at Casey. I'd like to think THAT is the record.</p>
<div align=center>
<a href="2020marker.html"><img src="calmarkerc1.jpg" width=500 height=473 alt="the 2021 Pole marker" title="sun, stars and station"></a><br>The 2021 Pole marker was designed by 2020 South Pole Telescope astronomer<br>Geoffrey Chen, who was still on station for the New Years Day unveiling. It was<br>fabricated by machinist Cal Neske, and it pays tribute to previous machinist Steele<br>Diggles who passed away at home in Tasmania in July. As of late January, he had<br>been scheduled to winter again in 2020. <a href="2020marker.html">Here's a look at the marker, its fabrication,<br>and the ceremony.</a>
</div>
<p>During the Navy days, none of the <span style="color: blue;" title="officer-in-charge">OIC</span>'s ever wintered more than once at Pole in any capacity, although several wintered elsewhere--including LT Jack Tuck who along with Paul Siple had wintered at McMurdo in 1956 before their 1957 Pole winter.</p>
<div align=center>
<a href="2019marker.html"><img src="kellymarker2.jpg" width=500 height=469 alt="the 2020 Pole marker" title="here's looking at you"></a><br>This is the amazing unique marker unveiled on 1 January 2020...designed by<br>2019 winterover Luis Gonzalez...who was actually around to unveil it! The<br>marker was constructed by that creative Aussie machinist Steele Diggles.<br><a href="2019marker.html">The details!!</a>
</div>
<p>News for the ages as it were, although I must note that due to that nasty pandemic that has been going around for 3 years now, older folks have at times been prevented from wintering due to their greater risk of contracting COVID-19. Anyway, 2018 winterover physician Malcolm Arnold is the oldest person to winter to date. He had that record in 2008 when he was 65 at the end of the winter...so ten years on he was 75 at the beginning of the winter (in 2019 he was at Palmer for the winter). He beat out 2011 physician Jim Borden who turned 74 in July of his winter. For the women, things are a bit more complicated. 2011 greenhouse tech Susan MacGregor (now Susan Batenhorst) had her 62nd birthday in mid-May of her winter (Susan was back at Pole for the 2019-20 summer). Dr. Betty Carlisle had her 63rd birthday after her 2001 winter ended, so she was 6 months older than Susan. But...Betty wasn't around for the entire winter, she showed up in April 2001 on the medevac that took out Dr. Ron Shemenski. So Susan is the oldest woman to spend an ENTIRE winter at Pole...as well as the oldest woman 300 club initiate. As for the youngest Polie winterovers, we had at least one in 2008: carpenter Andy Titterington and comms tech Shaun Meehan, were age 18 when they showed up at the beginning of the summer. Shaun turned 19 on 14 December, and Andy turned 19 a month later on 13 January, making Andy the youngest w/o Polie, beating out Larry Duckett, the 1975 winter cook, who was 19 when he showed up at the beginning of the 74-75 summer, and Eric Siefka, who was also 19 when he wintered in 1982. Oh, for 1 day there were 3 19-year-old w/o's on station, but UT Aditya Tata turned 20 on 14 January 2008. As for the youngest woman to winter..still researching that. Remember that all of these statistics are strictly voluntary...but one of the 2018 women was 22.</p>
<p>In 2007, Robert Schwarz alone held the record for six winters. But he wasn't back until 2011, so Johan Booth, Barry Horbal and Steffen Richter caught up with him in 2008, and Johan and Steff later passed him up. In 2013 Robert caught up with them, so the three of them (Johan, Steffen and Robert) all had 9 winters. In 2014, Robert and Johan were back again for winter #10. They were both back in 2015 for winter #11...and in 2016 for #12. Robert continued through 2019 and now has the record 15 winters, while Johan is back in 2020 for his 14th.</p>
<div align=center>
<a href="2018marker.html"><img src="steelemarker3.jpg" width=500 height=500 alt="the 2019 Pole marker" title="here's looking at you"></a><br>Here's the marker that was revealed on 1 January 2019. It was both designed and<br>created by winterover machinist Steele Diggles. <a href="2018marker.html">More information!</a>
</div>
<p>Behind Robert and Johan, Steffen Richter has 9 winters, and Barry Horbal and Dana Hrubes have 7. Two people have six winters: Bill Johnson as of 2020 and Dennis Calhoun in 2019; eight people have five winters: Tommy Barker, Tracy Blair, Steele Diggles, Heidi Lim, Rod Jensen, Lester Lemon, Clint Perrone, and Jake Speed (Joseph Gibbons). Jake was the first to reach this milestone. (He was back at Pole for awhile in the 2007-08 and 2008-09 summers, but he'd been spending some of the "off seasons" at Summit and/or with wife Kath) and after what happened to him in Greenland in 2009 he had to <a href="00s/jake/jakespeed.html">recover from losing some limbs at Summit</a>.</p>
<p>Eleven people have wintered a total of 4 times. This group includes Allan Day, Kaycee Flaugher, Weeks Heist, Travis Kamiya, Drew Logan, Paul Lux, Jason McDonald, Sue O'Reilly, Jack Sharp, Kevin Shea, and Kim Williams.</p>
<div align=center>
<a href="2017marker.html"><img src="keefemarker2.jpg" width=500 height=376 alt="the 2018 Pole marker" title="the heaviest marker yet"></a><br>This marker was revealed on 1 January 2018. It was a creation of IceCube winterover<br>Martin Wolf, BICEP3 winterover Grant Hall...and of course machinist Matt Krahn.<br><a href="2017marker.html">More photos and details...</a></div>
<p>With 3 winters, there now are 58 people, including 2023 winterovers Zeke Mills and Jonathon Weise. The full list: Derek Aboltins, Brien Barnett, Dave Benson, Kevin Berck, Hans Boenish, Rhys Boulton, Yubecca Bragg, Zane Burnette, Betty Carlisle, Robert (Gumby) Carlson, Clayton Cornia, Jeff De Rosa, Ethan Dicks, Nate Dyer, Terry Eddington, Tom Edwards, Lis Fano/Grillo, Ethan Good, John Hammon, Slay Harwell, Bill Henriksen, Katie Hess, Kitt Hughes, Katy Jensen/McNitt, Tim Korcal, Matthew Krahn, Ricardo Lopez, Erik Lund, Tim Markle, Janice Martin, Jon Martin, Sheri McKeen/Mason, Jason Medley, Jed Miller, Joshua Neff, Zeke Mills, Matt Newcomb, Jon Olander, Lee Parker, John Parlin, David Pernic, Kris Perry, Michael Rehm, John Richard, Elizabeth Rose, Eric Sandberg, Derek Sargent, Neal Scheibe, Mike Scholz, Rob Shaw, Will Silva, Paul Smith, Jason Spann, Bill Spindler, Leah Webster, Jonathon Weise, Noah White, and Wayne White. 179 people have wintered twice.</p>
<p>In 2019 Robert Schwarz was in his ninth consecutive winter, now well ahead of Jake Speed's five consecutive winters in 2000-2004. People with 4 consecutive winters include Kimberly Williams as of 2018, Kaycee Flaugher as of 2016, Heidi Lim and Kevin Shea as of 2008, and Allan Day and Barry Horbal as of 2006. The group with three consecutive winters now includes Brien Barnett, Johan Booth, Rhys Boulton, Clayton Cornia, Lester Lemon, Ricardo Lopez, Jason Medley, Sue O'Reilly, Michael Rehm, Steffen Richter, and Mike Scholz. No one else has more than two consecutive winters.</p>
<div align=center>
<a href="2016marker.html"><img src="gwenlargemarker1.jpg" width=500 height=500 border=0 alt="the 2017 Pole marker" title="getting eclipticed"></a><br>Here's the marker which was unveiled on 1 January 2017...a rather amazing bit of<br>machining, 3D assembly, and etching art. It was designed by fire tech Warren Shipley<br>and created by machinist Matthew Krahn <a href="2016marker.html">(info and photos).</a>
</div>
<p>In the new station era, there were only 43 people wintering in 2009--as construction on the new station was winding down. And there weren't any records in 2009...except perhaps that there were only 4 returning winterovers--an unusually low number for recent times. That low number is not at all unusual--in the old days there weren't many returnees--in my first 1977 winter we were all <span style="color: blue;" title="'friendly' new guys">FNG's</span>. All of the returning 2009 winterovers (Todd Adams, Weeks Heist, Lance Roth and Jack Sharp) were around with me in 2008 for their first winter.</p>
<p>This has brought up the question--how many women have wintered? Well, thanks to some male and female Pole Souls and Polies who helped me clear up my questions about ambiguous names, as of 2021, the total is 248. This includes one person, Heidi Lim (now married and named Heidi Rehm) with 5 winters, three--Sue O'Reilly, Kaycee Flaugher, and Kimberly Williams--with 4 winters, 12 with 3 winters, 29 with 2 winters, and 203 with one. The first woman was <a href="history/michele1.jpg">Michele Raney</a>, the doctor in 1979, and the second was <a href="http://antarcticnet.tripod.com/martha.jpg">Martha Kane Savage</a>, the cosray observer in 1980--both of whom are great people and good friends. Initially this was considered an "experiment" and there were only one or two women at Pole during the winter. Thankfully the powers-that-be decided to quit experimenting a few years later and get with the times.</p>
<div align=center>
<a href="2015marker.html"><img src="2016marker2.jpg" width=500 height=559 alt="the 2016 Pole marker" title="a whole new world"></a><br>The marker unveiled on 1 January 2016...a spinning world globe with the winterovers<br>engraved on the equator (!). This marker was both designed and created by the 2015<br>machinist Anton Brown. <a href="2015marker.html">(info and photos).</a>
</div>
<p><a name="all3">The</a> first woman to winter at all 3 of the current US stations was Carol Crossland...she wintered first at McMurdo in 1991, then (after a few summers here and there) at Pole in 1998 and Palmer Station in 1999. As for the second woman to do so (that I know about), she's Wendy Beeler, who wintered at Palmer in 2006, Pole in 1999, and McMurdo in 1992 and 1998. Yubecca Bragg completed the hat trick at McMurdo in 2008. More recently, Rachel Javorsek finished a 2012 winter at Palmer Station...she wintered at Pole in 2011 and at McM in 2008. And the newest addition to this list is Clair Von Handorf, who was at Pole in 2014 after wintering at McM in 2009 and at Palmer in 2010, 2011, and 2012. As for the men...it turns out there have been a number of them. The first of these was cook Harvey High, who wintered at all 3 stations with the Navy--1963 at McMurdo, 1966 at Pole, and 1970 at Palmer. Harvey was scheduled to winter at Pole with H&N in 1979 but he was medevaced with pancreatitis before station closing...and in 1982, while working as second mate on the <i>Hero</i>, he fell to his death from the ship to the drydock floor while the ship was in drydock in Talcahuano, Chile. Oh, the most recent addition to this list is satcom engineer Mike Rice, who wintered at Palmer for the 2018 winter after his most recent Pole winter in 2017. Interestingly, Mike showed up at Palmer along with FOUR other 2017 Pole winterovers! <!-- Bob DeValentino, who was the winter site manager at Palmer Station in 2013 and again for 2014. Bob reported that he'd spent at least one summer and at least one winter at all 3 stations, I'm not sure how many other folks can claim that. He's also done a <a href="http://forrestmccarthy.blogspot.com/2012/12/pig-traverse.html">traverse to <span style="color: blue;" title="Pine Island Glacier">PIG</span></a> and spent the summer there, not to mention a season in Greenland. -->Additionally (in no particular order as I don't have all the data) we have at least Robert (Gumby) Carlson, Larry Mjolsness, Jim "Thumper" Porter, Al O'Kelly, Paul Lux, Jordan Dickens, Jack Anderson, Brad Kuehn, Paul Daniels, Jed Miller, Damien Henning, Bob DeValentino, Zachary Morgan...I understand at least 39 folks may have wintered at all of the 3 current stations so I've obviously missed a few.</p>
<div align=center>
<a href="2014marker.html"><img src="2015marker2.jpg" width=500 height=357 alt="the 2015 Pole marker" title="Pole under glass"></a><br>The marker unveiled on 1 January 2015 was the biggest ever...it featured not only<br>rotation, but also (for the first time) some glass! It was designed and created by<br>2014 machinist Matt Krahn <a href="2014marker.html">(details and more photos).</a></div>
<p><a name="jules">Another</a> interesting overall program statistic...as of the 2022-23 summer season there was only one person on the ice for their 44th consecutive season...Rob Robbins! Jules Uberuaga, who was on the ice for 38 consecutive seasons through 2016-17, stayed home in 2017-18. For the past two seasons she'd been working as a grantee equipment operator for NASA's <span style="color: blue;" title="Long Duration Balloon">LDB</span> project...but that was cut back this year, so she stayed home in Idaho (and complained that there wasn't enough snow for skiing). Jules did her first season in 1979-80 as a GFA at Pole. She was interviewed by several TV stations in September 2012 before heading south for her 34th season...as of now, <a href="https://www.youtube.com/watch?v=XpdoXVlcWT8">this YouTube interview with Boise's KNIN is the only one still out there.</a> <!--KIVI TV (Boise) in September 2012 just before heading south. She was also interviewed in May 2012 by Boise TV station KTVB - <a href="http://legacy.ktvb.com/story/life/2014/06/30/11741409/">here's that uncut interview</a>. --> Rob's work involves diving...despite global warming, fortunately there is not much call for that specialty at Pole--yet. But Rob's long history in the program was noted in <a href="https://antarcticsun.usap.gov/features/4191">this November 2015 <i>Antarctic Sun</i> article</a>.</p>
<div align=center>
<a href="2013marker.html"><img src="2014marker2.jpg" width=500 height=375 alt="the South Pole marker installed on 1 January 2013" title="seeing stars"></a><br>
On 1 January 2014 the latest and greatest Pole marker (above) was unveiled. It was<br>designed by Dana Hrubes and created by machinist Steele Diggles...<a href="2013marker.html">(more photos and<br>information)</a>.</div>
<p>As for family members wintering, the most recent new statistic is from 2017 when two twin brothers, Jack and Ryan Clifford wintered together, both working in IT. The first two family members to winter at Pole (not in the same year) were brothers and scientists Henn Oona in 1964 and Hain Oona in 1968 (as of February 2012, Henn (Hank) and Hain were both still working at Los Alamos National Laboratory). Their family emigrated to the US from Estonia when they were young boys...so it also seems that Henn and Hain are the only two Estonian-born folks to winter. The second two brothers to winter were Bill Smythe (UCLA gravity, 1975) and brother Chuck (NOAA, 1979). There have since then been several married couples (as well as a few couples who met at Pole and got married later), as well as the father-son team of computer tech Cleve Cleavelin and his son Chris who wintered together in 1997.</p>
<div align=center>
<a href="2012marker.html"><img src="markertop3.jpg" width=500 height=333 alt="the South Pole marker installed on 1 January 2013" title="seeing stars"></a><br>
On New Years Day 2013, the marker which was both designed and created by 2012<br>machinist Derek Aboltins was revealed...featuring the alignment of the Sun, Moon,<br>planets, and the Southern Cross as located in the skies on 1 January. Here are more<br><a href="2012marker.html">pictures of the marker and the unveiling ceremony</a>.</div>
<p>2022 winterovers with nationalities other than American this year--the two IceCube grantees mentioned above--Mareno Baricevic (from Italy) and Celas Marie-Sainte (from France), Kiwi folks Sarah Boukoms--safety technician with dual citizenship and heavy equipment tech Anthony Barge who is employed by NZ equipment dealer Terra Cat, satcom engineer Hector Plaza--the first winterover from Colombia, power plant lead Seva Kotlyar who was born in Russia, and sous chef Niko Winegarner from Sweden. Note that the nationalities in these statistics include people who were originally from these countries or people with dual citizenship...and the nationality data I have is only from published information or what has been shared with me.</p>
<p>In 2016, the PM foreman Alex Teixeira was originally from <b>Uruguay</b>--the first from that nation. 2015 saw the first winterover <b>Thai</b>--met person Supria Calvert-Reisner--as well as the first <b>Iraqi</b>--facilities engineer Nizar Hashemi. In 2014, IceCuber Dag Larsen was the first <b>Norwegian</b> to winter--rather surprising considering that the first five Polie visitors who returned home to tell the tale were Norwegians.
In 2013, Ice Cube team member Felipe Pedreros Bustos was the first <b>Chilean</b> to winter at Pole, something a bit surprising given Chile's extensive involvement in the Antarctic over the years. And Blaise Kuo Tiong, the other IceCuber, was born in Manila--his family relocated from the <b>Philippines</b> to Los Angeles when he was nine. He's the second Filipino to winter...the first was Cesar Ambalada who wintered in 1966 as a US Navy EM1--electricians mate first class--quite impressive for the time, as few Filipinos in the Navy back then had technical rating jobs such as this. And in 2012, plumber Jean-Pierre (JP) Brunel, was the first <b>Québécois</b> to winter. JP grew up in Québec speaking only French until he moved to Colorado later in his adult life. </p>
<p>2012 brought the the third person from <b>Spain</b> to winter--Carlos Pobes was one of the two IceCube scientists. The first Spaniard to winter was US Weather Bureau meteorologist Luis Aldaz who wintered twice, as station science leader, in 1962 and 1965. The second was Francisco Navarro, a 1984 UCLA geophysics scientist.</p>
<div align=center>
<a href="2011marker.html"><img src="crop32b.jpg" width=500 height=470 alt="the South Pole marker installed on 1 January 2012" title="does Amundsen look fat?"></a><br>
1 January 2012...midway between the Amundsen and Scott centenary commemorations, yet<br> another fantastic Pole marker was unveiled. And again, it had moving parts, as well as that<br>enigmatic abbreviation <a href="lgn.html">"LGN"</a> which has appeared on many of these markers. Steele Diggles,<br>the machinist from Australia, created it, and, well, <a href="2011marker.html">check out more photos of the marker and<br>the unveiling!</a></div>
<p>The first <b>Japanese</b>-American to winter was US Weather Bureau researcher <a href="igy1/mayeda1.html">Fred Mayeda</a> in 1959...he'd become an American citizen. The first Japanese citizen showed up to winter a year later in 1960--Dr. Masakiyo (Henry) Morozumi who was studying auroras with the Arctic Institute of North America--he used to have a web site but he is still out there <!-- <a href="http://www.globalcyber.us/southpole59/">he has a web site</a> -->. Three more people wintered who were Japanese citizens or otherwise at the time--UCLA gravity researcher Tadashi Yogi in 1977, IceCuber Yuya Makino in 2020, and Michelle Endo in 2023 who was born of Chinese and Japanese parents, lived in Japan for awhile, and eventually chose American citizenship <a href="japan.html">(Japanese Polies)</a>. The first and only <b>Mexican</b>-American was Navy Seabee CMH2 (heavy construction mechanic second class) Jose Gomez in 1961...the first <b>African-American</b> was almost certainly Navy RM2 (radioman second class) <a href="igy2/1969/rod1.jpg" title="photo shared by OIC xx">Roderick H. (Henri) Miles</a> in 1969 (another African-American had wintered at Byrd in 1961).</p>
<p>The first Canadian to winter was 1973 Navy mechanic Gerald Davis who was originally from Canada. There have been a total of 18 folks with Canadian heritage, including 3 winter site managers. <a href="canada.html">Here's the list of all <b>Canadians</b>.</a></p>
<p>The first <b>Russian</b> (Soviet) exchange scientist was Peter Astakhov in 1967; he was followed 10 years later by Alex Zaitsev in 1977. A year later in 1978, Alex was followed up by Rurik M. Galkin in 1978, and Yuri Latov wintered in 1982. From the post-Soviet era, Russian Nikolai Makarov wintered in 1995, Ukrainian Nick (Nicolai) Starinski wintered in 1999, and most recently, Seva Kotlyar is wintering in 2022 as the power plant lead.</p>
<p>The first Kiwi men were met observers Barry Porter and Bernie Maguire in 1976, and the first NZ women were carpenters Kate Batten and Vicky Ward in 2005 <a href="kiwi.html">(the complete list of 27 <b>New Zealanders</b>).</a></p>
<p>The first Australian was Barry Woodberry who came down with the US National Bureau of Standards in 1966. The second Aussie is also notable--Graeme Currie wintered in 1981 (he wintered eleven times at various Australian and other stations)...the first Australian woman was AST/RO observer Jules Harnett in 2004. There have been at least 19 so far who have wintered, most recently including 2021 SPT researcher Matthew Young, 2020 SPT astronomer Geoffrey Chen, as well as 2019 machinist Steele Diggles and power plant mechanic Dennis Calhoun, who is a transplanted US-->Australian citizen <a href="aussies.html">(the list of <b>Australians</b>)</a>.</p>
<div align=center>
<a href="2010marker.html"><img src="sextant2.jpg" width=500 height=333 alt="the South Pole marker installed on 1 January 2011" title="where am I"></a><br>
On New Years Day 2011, this amazing marker made its appearance! The first with a finished<br>wood base and moving parts! An excellent South Pole marker for the centennial year of the<br>first visits to this place, long before there was a permanent station! This marker was designed<br>during the 2010 winter by David Holmes, and created by machinist Derek Aboltins. Here is <a href="2010marker.html">the<br>rest of the story</a> about the marker and the installation ceremony.</div>
<p>Speaking of winterovers from <b>Sweden</b>, there now are five--in 2022 sous chef Niko Winegarner is wintering. In 2019 materials person Viktor Barricklow returned (he also wintered in 2017 and has dual Swedish/US citizenship). SPT observer Daniel Michalik, with dual Swedish/German citizenship, wintered in 2017. Earlier, there were IceCube guy Sven Lidström; he wintered in 2007 and was back for 2012 (he also spent several summers at Pole and is currently working for Norway's Antarctic program), and cosray observer Lars Andersson in 1966.</p>
<p>From a bit south of Sweden in the Low Countries, there have been two <b>Belgians</b>--Freija Descamps, one of the 2011 IceCube observers, and Jean-Marie Moreau, the 1990 doctor. And Erik Verhagen, with IceCube in 2009, was the first <b>Netherlands</b> citizen to winter.</p>
<p><a href="noahwhite1.jpg" title="Noah at the 2002 OAEA reunion in Pensacola">Noah White</a>, radioman/comms guy, wintered three times in 1967, 1970, and 1979. He's the only person to winter both at the original station (Old Pole) and under the dome, the only person to winter both as a Navy man and a civilian, and the first person to winter three times. Yes, I've met him, he was a good guy, sadly, he passed away in early 2019.</p>
<p>1995 and 1996 were interesting winters...1995 was the last year WITH a scheduled midwinter airdrop and WITHOUT internet. They also were the first years when anyone wintered consecutively--Australian astronomer James (Jamie) Lloyd and NOAA science tech Jeff Otten wintered in both 1995 and 1996.</p>
<p>Back to nationalities...it now seems that the first German to winter did so back in the real old days of 1972--gravity geophysicist and German citizen Walter Zürn, who was spending time at UCLA after graduation from Stuttgart. Next was 1983 w/o geophysicist Hans-Albert Dahlheim, who was studying the gravitational pull of the Moon (and won the Round the World Race). Matthias Rumitz (AST/RO) and Robert Schwarz (AMANDA) were next, in 1997. By now there are twenty total...here is <a href="germans.html">the list of <b>Germans</b></a>. As for the <b>French</b>, probably the title for the first man goes to the 2006 BICEP researcher Denis Barkats, and 2009 IceCube w/o Camille Parisel is the first woman--she previously spent 14 months at Dumont d'Urville through the 2001 winter. And in 2022, IceCube grantee Celas Marie-Sainte, is also from France. There have been three <b>Italians</b>--Moreno Baricevic, one of the 2022 IceCube grantees; the 2018 WSM Marco Tortonese, who also wintered in 2011 as a science tech; and the first Italian was Paolo Calisse, the 2003 VIPER/AASTO winterover. 2010 (and 2011 and 2012) brought Ricardo Lopez, the first Polie originally from the <b>Dominican Republic</b>, and 2005 featured the first <b>Jamaican</b>, fellow winterover and HR person Kurt Montas.</p>
<div align=center>
<a href="2009marker.html"><img src="2010marker3.jpg" width=500 height=520 alt="the South Pole marker installed on 1 January 2010" title="LGN"></a><br>
This unique 2010 marker features the South Pole Telescope along with 43 IceCube DOMs,<br>one for each of the 2009 wo's.It was designed and fabricated by the 2009 SCOARA machinist<br><a href="http://antarcticsun.usap.gov/features/contenthandler.cfm?id=1836" title="Antarctic Sun article">Steele Diggles</a>. More <a href="2009marker.html">information and photos by Forest Banks,</a> including the placement ceremony<br>on New Years Day...
</div>
<p>Laser scientist Ashraf El-Dakrouri, who wintered in 2000, was the first <b>Egyptian</b> (and the first person from any Arab or Muslim nation) to winter at Pole <a href="antsun20000116ashraf.pdf">(profile article</a> from the 16 January 2000 <i>Antarctic Sun</i>). Hein Van Bui, the 1988 w/o computer tech, was the first person from <b>Vietnam</b> to winter. He was followed by Hien Nguyen, the 1994 SPIREX researcher/SSL; and Xuan Ta, the 2004 Title II inspector. There have been four <b>Chinese</b> (<span style="color: blue;" title="People's Republic of China">PRC</span>) citizens to winter: AST/RO astronomer Xiaolei Zhang (1998), AMANDA researcher Xinhua Bai (1999),Kecheng Xiao (AST/RO, 2002), and electrician Hung So (2010).</p>
<p>We've had four people from <b>India</b> winter...the first was Roopesh Ojha, a citizen of the Republic of India who wintered with CARA/ASTRO in 1999. Also there with him that year was science tech Reza Mossadeque (of Indian and Bangladeshi origin, although he was an American citizen when he wintered). Next was 2007 w/o Karthik Soundarapandian, another India citizen, who wintered and is currently working with IceCube. More recently, Aman Chokshi wintered in 2022 with SPT.</p>
<p>From the UK I believe we have had fifteen winterovers (which includes a couple of folks with dual NZ/British citizenship), the most recent one wintered in 2021--IceCube researcher Joshua Veitch-Michaelis <a href="uk.html">(list of <b>British</b> citizens)</a>. And from an emerald island next to the UK it seems 2010 winter site manager Mel MacMahon claims both Irish and Canadian heritage, and 1990 CUSP associate Richard Collins was an Irish citizen.</p>
<p>From elsewhere in Europe, note that 2012 cook Kate McGrew was the first <b>Pole</b> to winter at Pole (!) From a bit south of there, Monique Gerbex, the 2003 work order planner, hailed from <b>Switzerland</b>. Speaking of Switzerland, 2023 IceCube winterover Marc Jacquart also hails from there...and not winterover statistics but important to me...one of the <span style="color: blue;" title="general field assistants">GFA</span>s who was with us in 1976-77, the late Dave Pluth, turned up at our 2007 Pole Soul reunion in Boulder to tell us that he'd become a Swiss citizen. Finally, back in the US of A (but not the 50 states), electrician Osvaldo Torres, who wintered in 2004, is from <b>Puerto Rico</b>.</p>
<div align=center>
<a href="globea1.jpg"><img src="globea2.jpg" width=500 height=375 alt="the South Pole marker installed on 1 January 2009" title="59 wankers and me"></a><br>
The 1 January 2009 marker seen here was designed and created by the 2008 w/o<br>SCOARA machinist Dave Postler This photo is by Reinhart Piuk. <a href="2008marker.html">More on the<br>marker and the New Years Day ceremony</a>...
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<p>Some station management statistics (these refer to the winter site manager, not the area manager/resident manager position, which was created for the first time for the 1977-78 summer). The year before then, the station manager had, shall I say (since it was I ;-), a bit more to do during the summer: For the 2005 winter--Bill Henriksen was the first person to return for the second time as manager--in 2003 he had the same job (his first winter was as Title II inspector in 2000). In 2006 through 2018 he wintered in McMurdo as the NSF manager. Katie Hess, the 2008 manager, returned to do that again in 2012. Janet Phillips in 1994 was the first female manager. After the McMurdo winfly, all 3 US stations had female management for the first time--Karen Schwall at McM and Ann Peoples at Palmer as well as Janet <a href="90s/janet.html">(her article about the experience)</a>. Oh, Janet went on to manage Palmer Station in 1996. Speaking of Palmer Station...AFAIK the record of the most times as winter site manager anywhere goes to Ken Keenan...his first winter was at Pole with me in 2005, but subsequently he's been the Palmer winter site manager nine times between 2009 and 2022.</p>
<p>Three managers during the civilian era were last-minute replacements--Dan Morton in 1976, Rich Wiik in 1983, and Dennis O'Neill in 1991. Rich and Dennis had been at Pole, scheduled to winter in other positions, but Dan had NOT worked at Pole and was not originally scheduled to winter until 1977. All 3 guys are friends of mine and did well.</p>
<div align=center>
<a href="2008polemarker1.jpg"><img src="2008polemarker2.jpg" width=500 height=332 alt="the South Pole marker installed on 1 January 2008" title="arching"></a><br>
Here's the marker placed on 1 January 2008, designed by 2007 w/o facilities engineer<br>Laura Rip...and created by SCOARA machinist Derek Aboltins. Photo courtesy Glenn<br>Grant (whom I finally got to meet in person!). <a href="2007marker.html">More information about the marker and<br>photos of the ceremony are here</a>.</div>
<p><a name="max">Last</a> but not least, some statistics that had nothing to do with Pole until 2014. For a number of years since 2004, power plant mechanic Rocky (Gerald or Gerry) Ness held the all-time record for 15 Antarctic winters--all at Palmer and McMurdo. But in 2014 that record was broken by two people. At McMurdo, George Lampman had his sixteenth CONSECUTIVE winter...all of them at McMurdo, more recently as operations supervisor. He was documented in the film <a href="http://frozensouth.weebly.com/">Antarctica: A Year On Ice</a>. And at Pole, Johan Booth also had his 16th winter in 2016, none of which have been at McMurdo. Both George and Johan had their 17th winters in 2015. Johan had his 18th winter in 2016. but George did not. As of 2016 the undisputed record holder for women was Wendy Kober who had her 15th winter that year. Previously in 2015 Wendy had tied Angela Garner at 14 winters. Angela wintered again in 2017, so the two women Wendy and Angela are still tied at 15 winters.</p>
<p>Back to the men...the person with the most total Antarctic winters is...Rex Cotten! He is wintering at McMurdo in 2023--his 23rd winter, again monitoring the NASA McMurdo Ground Station, a 10-meter antenna which monitors and downloads data from polar-orbiting science satellites...a mission which has gotten much more useful with the availability of the new internet earth station at McMurdo <a href="https://www.usap.gov/sciencesupport/scienceplanningsummaries/2022_2023/results.cfm?formAction=detail&ID=204">(more project info from the NSF Science Planning Summary)</a>. All of his winters are consecutive (I think). At one time, he and the late Johan Booth (alas, Johan passed away from cancer on 29 June 2022 <a href="20s/johan.html">obituary</a>) were tied for 20 winters. Johan wintered six times at Palmer between 1994 and 2004, and 14 times at Pole between 1995 and 2020. The twists...Rex's winters have all been at McMurdo, while all of Johan's winters have been at Palmer and Pole. All of course in Antarctica, and of course all of Rex's winters have been south of the Antarctic Circle.</p>
<p>Yes, I know, there must be more vital stats--<a href="../info.html">send em to me!!</a></p>
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<a href="2007polemarker1.jpg"><img src="2007polemarker2.jpg" width=500 height=332 alt="the South Pole marker installed on 1 January 2007" title="I am NOT one of the 64 dimples, but I am homesick"></a><br>The 2007 Pole marker (<a href="http://photolibrary.usap.gov/">Antarctic photo library</a>, photo by Glenn Grant). The marker was<br>
designed by 2006 (and 2005 :) AND 2004 w/o electrician Clayton Cornia. Yes...once<br>again, each dimple represents one of the 64 winterovers.</div>
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<div align=center><a href="1996marker.html"><img src="1997marker3.jpg" width=300 height=298 alt="the Pole marker installed in January 1997" title="Dave Pernic does it at Pole"></a></div><br>Okay...as a bit of trivia I must add this bit of information about the 1997 Pole marker, as I get asked about this now and then. A summer visitor acquired a copy of it and later tried to sell it...on an episode of <i>Pawn Stars</i> first aired by the History Channel in December 2009. The episode gets aired now and again more recently, and it's also available online...<a href="1996marker.html">hence these details</a>.</td>
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<div align=center><a href="1996marker.html"><img src="bm2.jpg" width=291 height=298 alt="the Pole marker installed in November 1976" title="someone stole this"></a></div><br>This was the first Pole marker I was ever aware of...some USGS folks showed up to install it in November 1976 to mark the American centennial. Based on the dates, I assumed that they'd planned to show up with it a year earlier, but in 1975-76 flights and visits were severely curtailed because of the 3 LC-130's that had crashed at Dome C. Oh, this marker was stolen less than a day later <a href="../pole/survey.html">(more info from my 1976-77 winterover pages)</a>.</td>
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<div align=center><a href="igy1/firstmarker.html"><img src="igy1/firstmarker2a.jpg" width=357 height=298 alt="the very first Pole marker from 1959-60" title="not placed at the geographic pole"></a></div><br>Above...an image of the very first (and long-lost) South Pole marker, manufactured in Washington DC and hand-carried to the station during the 1959-60 season. It does not say "90º South" as it was not placed at the Pole, but inside the original station, where it presumably still is today. As with the one at left, multiple copies of it have been in play-- most recently, it was up on eBay in January 2016 (it didn't sell). <a href="igy1/firstmarker.html">Here's the rest of that story</a>.</td></tr>
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<p>Thanks to Katy Jensen, who originally crunched the data to produce many of the statistics you see here. Credits for the photos at the top of the page--the group in the left photo is the 1957 team, note Paul Siple in the back row <a href="igy1/1957.html">(caption and more information)</a>; and the motley crew in the right photo is, of course, <a href="../pole/whoarewe.html">us 1977 Pole Souls</a> :). The panorama below is <a href="00s/2004.html">the 2004 w/o picture</a>, by Glen Kinoshita.</p>
<p>Another disclaimer...again the nationality statistics seen here are strictly voluntary or from officially published information and include folks who were born and/or are or were citizens of the indicated countries.</p>
<img src="polepan2.jpg" width=1200 height=87 alt="a small group of friends" title="a small group of friends">
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Winterover Statistics
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| [this place is going to the dogs already](igy1/1957.html)
[1977 winterovers](77march.html)
Winterover Statistics
1702 people have wintered over at least once at the South Pole from 1957 through 2023. Since some of these folks wintered more than once, there actually have been a total of 2124 winterover positions. And if you haven't found the winterover lists yet, they are included, along with photos and other information as available, in the [timeline entries](trivia.html) for each year through 2022 at this point. Actually I should also say that there is a complete database spreadsheet, with winterover numbers, updated to date, on this web site, slightly hidden to protect the list of names from spammers. Access is available to Polies upon request. Although it is obvious that I've made errors and omissions in the past, I'm pretty confident that the basic list of folks is complete and accurate, if only because it has been more than 16 years since someone wrote me claiming I'd left someone out :) Suggestions/corrections...[please let me know!](../info.html)
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| [Photos of South Pole winterovers in the A3 second floor hallway](06_winterover_lineup1.jpg) | At left, a view of the main second floor hallway and the gallery of winterover pictures dating from 2012 back to the first winter in 1957...most of these were hung, edited and/or reframed by Andy Martinez and Terry Eddington during the 2007 winter [(*Antarctic Sun* article)](http://antarcticsun.usap.gov/features/contentHandler.cfm?id=1208). Some of the frames were fabricated with wood from the old Dome sauna or gym floor. We are still missing a few pictures...1960, 1962, 1963, and 1968 from the Navy days and 1976, 1979, and 1986 from the dome era--you know who you are :). This photo by 2012 SPT winterover [Cynthia Chiang](http://www.physicschick.com) shows those [2011](10s/2011.html) and [2012](10s/2012.html) photos that include the members of Amundsen's and Scott's parties.
As the north wall of the hallway is now filled with photos, the more recent winterover photos are being hung on the south wall. |
In 2023 there are 43 [NPX](npx.html) winterovers...about average since construction completion of the elevated station, and the group includes 6 women and 37 men. In 1998-99, when construction began on the first phase of the new station (the fuel arch in the summer and the heavy shop in summer/winter)...there were 41 winterovers...before that there were never more than 28 winterovers. The largest crowd ever was my 2005 winter when we had 86 folks, including 24 women! In the old days, the first three years with women (1979-81) the crews included only one woman--in hindsight that experiment was probably not the best idea.
Seven of the 2023 winterovers have previously wintered at least once...a drop from 2022 when there were 12 repeaters among the 44 winterovers. The 2023 people with multiple winters include food services supervisor Zeke Mills and Jonathon Weise with 3 winters, as well as satcom engineer Ryan Gutierrez, power plant lead mechanic Seva Kotlyar, supply tech Tammy McDermott, SPT grantee Cal Neske, and network engineer Christian Rahl with 2 winters.
2023 winterover nationalities...there are three new countries represented this year--IceCube observer Hrvoje Dujmovic is from Croatia, heavy equipment operator Federico Piola is from Argentina, and Naweed Hashimi is of Afghan heritage. Power plant mechanic Seva Kotyar from Russia has returned for his second winter in a row, and IceCube grantee Marc Jacquart is the second winterover from Switzerland...the first was 2003 maintenance scheduler Monique Gerbex who was born in Switzerland and later lived in Vermont. Supply technician Jaden Pan was born and raised in Toronto. And...Michelle Endo is the first woman winterover with Japanese heritage...there have now been five Japanese winterovers [(list)](japan.html).
2022 international stuff...both IceCube winterovers Mareno Baricevic (from Italy) and Celas Marie-Sainte (from France) have previously wintered at the Italian/French station Concordia located at Dome C...a bit higher up than Pole at 10,607 feet/3,233 meters altitude.
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| [winter side of the marker](2022marker.html) | [summer side of the marker](2022marker.html) |
Above...both the winter and summer sides of the marker that was revealed to the world on 1 January 2023. It was fabricated bywinterover Thomas Leps...who actually didn't get it 100 % finished until just before he left in late January. [Details and photos!](2022marker.html)
In the 2020 winter there was a new record regarding the winter site manager position. Previously 3 people have held that job twice--Bill Henriksen in 2003 and 2005, Katie Hess in 2008 and 2012, and Wayne White in 2017 and 2019. But for 2020 Wayne has returned for his third time as manager...and in two consecutive years (he did take some time away during the summer). Bill and Katie each wintered 3 times, but their first winters were in other positions.
[the 2022 Pole marker](2021marker.html)
Above, the 2022 Pole marker unveiled on New Years Day...designed by BICEP Array winterover BrandonAmat and amazingly fabricated by Dave Pernic...not his first marker fabrication! [More information!](2021marker.html)
During the Dome era, many of the managers had previously wintered in another position--the first of these being Tom Plyler who was the power plant mechanic in 1975 and manager in 1981. Now, three managers to date have subsequently returned to winter again in another position: Don McCreight was the manager in 1997--he returned in 2015 to winter as carpenter foreman (and has been back for some other summers as well). Gary Freeman was manager in 1992 and returned as SEH coordinator in 1995. And Bill Spindler, who was manager in 1977, returned to winter in 2005 as Title II inspector and in 2008 as a project engineer--with a gap of 28 years between his 1977 and 2005 winters. That is not an overall Antarctic record; Australian Brian Jury wintered at Mawson in 2017, 31 years before that he wintered at Casey. I'd like to think THAT is the record.
[the 2021 Pole marker](2020marker.html)The 2021 Pole marker was designed by 2020 South Pole Telescope astronomerGeoffrey Chen, who was still on station for the New Years Day unveiling. It wasfabricated by machinist Cal Neske, and it pays tribute to previous machinist SteeleDiggles who passed away at home in Tasmania in July. As of late January, he hadbeen scheduled to winter again in 2020. [Here's a look at the marker, its fabrication,and the ceremony.](2020marker.html)
During the Navy days, none of the OIC's ever wintered more than once at Pole in any capacity, although several wintered elsewhere--including LT Jack Tuck who along with Paul Siple had wintered at McMurdo in 1956 before their 1957 Pole winter.
[the 2020 Pole marker](2019marker.html)This is the amazing unique marker unveiled on 1 January 2020...designed by2019 winterover Luis Gonzalez...who was actually around to unveil it! Themarker was constructed by that creative Aussie machinist Steele Diggles.[The details!!](2019marker.html)
News for the ages as it were, although I must note that due to that nasty pandemic that has been going around for 3 years now, older folks have at times been prevented from wintering due to their greater risk of contracting COVID-19. Anyway, 2018 winterover physician Malcolm Arnold is the oldest person to winter to date. He had that record in 2008 when he was 65 at the end of the winter...so ten years on he was 75 at the beginning of the winter (in 2019 he was at Palmer for the winter). He beat out 2011 physician Jim Borden who turned 74 in July of his winter. For the women, things are a bit more complicated. 2011 greenhouse tech Susan MacGregor (now Susan Batenhorst) had her 62nd birthday in mid-May of her winter (Susan was back at Pole for the 2019-20 summer). Dr. Betty Carlisle had her 63rd birthday after her 2001 winter ended, so she was 6 months older than Susan. But...Betty wasn't around for the entire winter, she showed up in April 2001 on the medevac that took out Dr. Ron Shemenski. So Susan is the oldest woman to spend an ENTIRE winter at Pole...as well as the oldest woman 300 club initiate. As for the youngest Polie winterovers, we had at least one in 2008: carpenter Andy Titterington and comms tech Shaun Meehan, were age 18 when they showed up at the beginning of the summer. Shaun turned 19 on 14 December, and Andy turned 19 a month later on 13 January, making Andy the youngest w/o Polie, beating out Larry Duckett, the 1975 winter cook, who was 19 when he showed up at the beginning of the 74-75 summer, and Eric Siefka, who was also 19 when he wintered in 1982. Oh, for 1 day there were 3 19-year-old w/o's on station, but UT Aditya Tata turned 20 on 14 January 2008. As for the youngest woman to winter..still researching that. Remember that all of these statistics are strictly voluntary...but one of the 2018 women was 22.
In 2007, Robert Schwarz alone held the record for six winters. But he wasn't back until 2011, so Johan Booth, Barry Horbal and Steffen Richter caught up with him in 2008, and Johan and Steff later passed him up. In 2013 Robert caught up with them, so the three of them (Johan, Steffen and Robert) all had 9 winters. In 2014, Robert and Johan were back again for winter #10. They were both back in 2015 for winter #11...and in 2016 for #12. Robert continued through 2019 and now has the record 15 winters, while Johan is back in 2020 for his 14th.
[the 2019 Pole marker](2018marker.html)Here's the marker that was revealed on 1 January 2019. It was both designed andcreated by winterover machinist Steele Diggles. [More information!](2018marker.html)
Behind Robert and Johan, Steffen Richter has 9 winters, and Barry Horbal and Dana Hrubes have 7. Two people have six winters: Bill Johnson as of 2020 and Dennis Calhoun in 2019; eight people have five winters: Tommy Barker, Tracy Blair, Steele Diggles, Heidi Lim, Rod Jensen, Lester Lemon, Clint Perrone, and Jake Speed (Joseph Gibbons). Jake was the first to reach this milestone. (He was back at Pole for awhile in the 2007-08 and 2008-09 summers, but he'd been spending some of the "off seasons" at Summit and/or with wife Kath) and after what happened to him in Greenland in 2009 he had to [recover from losing some limbs at Summit](00s/jake/jakespeed.html).
Eleven people have wintered a total of 4 times. This group includes Allan Day, Kaycee Flaugher, Weeks Heist, Travis Kamiya, Drew Logan, Paul Lux, Jason McDonald, Sue O'Reilly, Jack Sharp, Kevin Shea, and Kim Williams.
[the 2018 Pole marker](2017marker.html)This marker was revealed on 1 January 2018. It was a creation of IceCube winteroverMartin Wolf, BICEP3 winterover Grant Hall...and of course machinist Matt Krahn.[More photos and details...](2017marker.html)
With 3 winters, there now are 58 people, including 2023 winterovers Zeke Mills and Jonathon Weise. The full list: Derek Aboltins, Brien Barnett, Dave Benson, Kevin Berck, Hans Boenish, Rhys Boulton, Yubecca Bragg, Zane Burnette, Betty Carlisle, Robert (Gumby) Carlson, Clayton Cornia, Jeff De Rosa, Ethan Dicks, Nate Dyer, Terry Eddington, Tom Edwards, Lis Fano/Grillo, Ethan Good, John Hammon, Slay Harwell, Bill Henriksen, Katie Hess, Kitt Hughes, Katy Jensen/McNitt, Tim Korcal, Matthew Krahn, Ricardo Lopez, Erik Lund, Tim Markle, Janice Martin, Jon Martin, Sheri McKeen/Mason, Jason Medley, Jed Miller, Joshua Neff, Zeke Mills, Matt Newcomb, Jon Olander, Lee Parker, John Parlin, David Pernic, Kris Perry, Michael Rehm, John Richard, Elizabeth Rose, Eric Sandberg, Derek Sargent, Neal Scheibe, Mike Scholz, Rob Shaw, Will Silva, Paul Smith, Jason Spann, Bill Spindler, Leah Webster, Jonathon Weise, Noah White, and Wayne White. 179 people have wintered twice.
In 2019 Robert Schwarz was in his ninth consecutive winter, now well ahead of Jake Speed's five consecutive winters in 2000-2004. People with 4 consecutive winters include Kimberly Williams as of 2018, Kaycee Flaugher as of 2016, Heidi Lim and Kevin Shea as of 2008, and Allan Day and Barry Horbal as of 2006. The group with three consecutive winters now includes Brien Barnett, Johan Booth, Rhys Boulton, Clayton Cornia, Lester Lemon, Ricardo Lopez, Jason Medley, Sue O'Reilly, Michael Rehm, Steffen Richter, and Mike Scholz. No one else has more than two consecutive winters.
[the 2017 Pole marker](2016marker.html)Here's the marker which was unveiled on 1 January 2017...a rather amazing bit ofmachining, 3D assembly, and etching art. It was designed by fire tech Warren Shipleyand created by machinist Matthew Krahn [(info and photos).](2016marker.html)
In the new station era, there were only 43 people wintering in 2009--as construction on the new station was winding down. And there weren't any records in 2009...except perhaps that there were only 4 returning winterovers--an unusually low number for recent times. That low number is not at all unusual--in the old days there weren't many returnees--in my first 1977 winter we were all FNG's. All of the returning 2009 winterovers (Todd Adams, Weeks Heist, Lance Roth and Jack Sharp) were around with me in 2008 for their first winter.
This has brought up the question--how many women have wintered? Well, thanks to some male and female Pole Souls and Polies who helped me clear up my questions about ambiguous names, as of 2021, the total is 248. This includes one person, Heidi Lim (now married and named Heidi Rehm) with 5 winters, three--Sue O'Reilly, Kaycee Flaugher, and Kimberly Williams--with 4 winters, 12 with 3 winters, 29 with 2 winters, and 203 with one. The first woman was [Michele Raney](history/michele1.jpg), the doctor in 1979, and the second was [Martha Kane Savage](http://antarcticnet.tripod.com/martha.jpg), the cosray observer in 1980--both of whom are great people and good friends. Initially this was considered an "experiment" and there were only one or two women at Pole during the winter. Thankfully the powers-that-be decided to quit experimenting a few years later and get with the times.
[the 2016 Pole marker](2015marker.html)The marker unveiled on 1 January 2016...a spinning world globe with the winteroversengraved on the equator (!). This marker was both designed and created by the 2015machinist Anton Brown. [(info and photos).](2015marker.html)
The first woman to winter at all 3 of the current US stations was Carol Crossland...she wintered first at McMurdo in 1991, then (after a few summers here and there) at Pole in 1998 and Palmer Station in 1999. As for the second woman to do so (that I know about), she's Wendy Beeler, who wintered at Palmer in 2006, Pole in 1999, and McMurdo in 1992 and 1998. Yubecca Bragg completed the hat trick at McMurdo in 2008. More recently, Rachel Javorsek finished a 2012 winter at Palmer Station...she wintered at Pole in 2011 and at McM in 2008. And the newest addition to this list is Clair Von Handorf, who was at Pole in 2014 after wintering at McM in 2009 and at Palmer in 2010, 2011, and 2012. As for the men...it turns out there have been a number of them. The first of these was cook Harvey High, who wintered at all 3 stations with the Navy--1963 at McMurdo, 1966 at Pole, and 1970 at Palmer. Harvey was scheduled to winter at Pole with H&N in 1979 but he was medevaced with pancreatitis before station closing...and in 1982, while working as second mate on the *Hero*, he fell to his death from the ship to the drydock floor while the ship was in drydock in Talcahuano, Chile. Oh, the most recent addition to this list is satcom engineer Mike Rice, who wintered at Palmer for the 2018 winter after his most recent Pole winter in 2017. Interestingly, Mike showed up at Palmer along with FOUR other 2017 Pole winterovers! Additionally (in no particular order as I don't have all the data) we have at least Robert (Gumby) Carlson, Larry Mjolsness, Jim "Thumper" Porter, Al O'Kelly, Paul Lux, Jordan Dickens, Jack Anderson, Brad Kuehn, Paul Daniels, Jed Miller, Damien Henning, Bob DeValentino, Zachary Morgan...I understand at least 39 folks may have wintered at all of the 3 current stations so I've obviously missed a few.
[the 2015 Pole marker](2014marker.html)The marker unveiled on 1 January 2015 was the biggest ever...it featured not onlyrotation, but also (for the first time) some glass! It was designed and created by2014 machinist Matt Krahn [(details and more photos).](2014marker.html)
Another interesting overall program statistic...as of the 2022-23 summer season there was only one person on the ice for their 44th consecutive season...Rob Robbins! Jules Uberuaga, who was on the ice for 38 consecutive seasons through 2016-17, stayed home in 2017-18. For the past two seasons she'd been working as a grantee equipment operator for NASA's LDB project...but that was cut back this year, so she stayed home in Idaho (and complained that there wasn't enough snow for skiing). Jules did her first season in 1979-80 as a GFA at Pole. She was interviewed by several TV stations in September 2012 before heading south for her 34th season...as of now, [this YouTube interview with Boise's KNIN is the only one still out there.](https://www.youtube.com/watch?v=XpdoXVlcWT8) Rob's work involves diving...despite global warming, fortunately there is not much call for that specialty at Pole--yet. But Rob's long history in the program was noted in [this November 2015 *Antarctic Sun* article](https://antarcticsun.usap.gov/features/4191).
[the South Pole marker installed on 1 January 2013](2013marker.html)
On 1 January 2014 the latest and greatest Pole marker (above) was unveiled. It wasdesigned by Dana Hrubes and created by machinist Steele Diggles...[(more photos andinformation)](2013marker.html).
As for family members wintering, the most recent new statistic is from 2017 when two twin brothers, Jack and Ryan Clifford wintered together, both working in IT. The first two family members to winter at Pole (not in the same year) were brothers and scientists Henn Oona in 1964 and Hain Oona in 1968 (as of February 2012, Henn (Hank) and Hain were both still working at Los Alamos National Laboratory). Their family emigrated to the US from Estonia when they were young boys...so it also seems that Henn and Hain are the only two Estonian-born folks to winter. The second two brothers to winter were Bill Smythe (UCLA gravity, 1975) and brother Chuck (NOAA, 1979). There have since then been several married couples (as well as a few couples who met at Pole and got married later), as well as the father-son team of computer tech Cleve Cleavelin and his son Chris who wintered together in 1997.
[the South Pole marker installed on 1 January 2013](2012marker.html)
On New Years Day 2013, the marker which was both designed and created by 2012machinist Derek Aboltins was revealed...featuring the alignment of the Sun, Moon,planets, and the Southern Cross as located in the skies on 1 January. Here are more[pictures of the marker and the unveiling ceremony](2012marker.html).
2022 winterovers with nationalities other than American this year--the two IceCube grantees mentioned above--Mareno Baricevic (from Italy) and Celas Marie-Sainte (from France), Kiwi folks Sarah Boukoms--safety technician with dual citizenship and heavy equipment tech Anthony Barge who is employed by NZ equipment dealer Terra Cat, satcom engineer Hector Plaza--the first winterover from Colombia, power plant lead Seva Kotlyar who was born in Russia, and sous chef Niko Winegarner from Sweden. Note that the nationalities in these statistics include people who were originally from these countries or people with dual citizenship...and the nationality data I have is only from published information or what has been shared with me.
In 2016, the PM foreman Alex Teixeira was originally from **Uruguay**--the first from that nation. 2015 saw the first winterover **Thai**--met person Supria Calvert-Reisner--as well as the first **Iraqi**--facilities engineer Nizar Hashemi. In 2014, IceCuber Dag Larsen was the first **Norwegian** to winter--rather surprising considering that the first five Polie visitors who returned home to tell the tale were Norwegians.
In 2013, Ice Cube team member Felipe Pedreros Bustos was the first **Chilean** to winter at Pole, something a bit surprising given Chile's extensive involvement in the Antarctic over the years. And Blaise Kuo Tiong, the other IceCuber, was born in Manila--his family relocated from the **Philippines** to Los Angeles when he was nine. He's the second Filipino to winter...the first was Cesar Ambalada who wintered in 1966 as a US Navy EM1--electricians mate first class--quite impressive for the time, as few Filipinos in the Navy back then had technical rating jobs such as this. And in 2012, plumber Jean-Pierre (JP) Brunel, was the first **Québécois** to winter. JP grew up in Québec speaking only French until he moved to Colorado later in his adult life.
2012 brought the the third person from **Spain** to winter--Carlos Pobes was one of the two IceCube scientists. The first Spaniard to winter was US Weather Bureau meteorologist Luis Aldaz who wintered twice, as station science leader, in 1962 and 1965. The second was Francisco Navarro, a 1984 UCLA geophysics scientist.
[the South Pole marker installed on 1 January 2012](2011marker.html)
1 January 2012...midway between the Amundsen and Scott centenary commemorations, yet another fantastic Pole marker was unveiled. And again, it had moving parts, as well as thatenigmatic abbreviation ["LGN"](lgn.html) which has appeared on many of these markers. Steele Diggles,the machinist from Australia, created it, and, well, [check out more photos of the marker andthe unveiling!](2011marker.html)
The first **Japanese**-American to winter was US Weather Bureau researcher [Fred Mayeda](igy1/mayeda1.html) in 1959...he'd become an American citizen. The first Japanese citizen showed up to winter a year later in 1960--Dr. Masakiyo (Henry) Morozumi who was studying auroras with the Arctic Institute of North America--he used to have a web site but he is still out there . Three more people wintered who were Japanese citizens or otherwise at the time--UCLA gravity researcher Tadashi Yogi in 1977, IceCuber Yuya Makino in 2020, and Michelle Endo in 2023 who was born of Chinese and Japanese parents, lived in Japan for awhile, and eventually chose American citizenship [(Japanese Polies)](japan.html). The first and only **Mexican**-American was Navy Seabee CMH2 (heavy construction mechanic second class) Jose Gomez in 1961...the first **African-American** was almost certainly Navy RM2 (radioman second class) [Roderick H. (Henri) Miles](igy2/1969/rod1.jpg "photo shared by OIC xx") in 1969 (another African-American had wintered at Byrd in 1961).
The first Canadian to winter was 1973 Navy mechanic Gerald Davis who was originally from Canada. There have been a total of 18 folks with Canadian heritage, including 3 winter site managers. [Here's the list of all **Canadians**.](canada.html)
The first **Russian** (Soviet) exchange scientist was Peter Astakhov in 1967; he was followed 10 years later by Alex Zaitsev in 1977. A year later in 1978, Alex was followed up by Rurik M. Galkin in 1978, and Yuri Latov wintered in 1982. From the post-Soviet era, Russian Nikolai Makarov wintered in 1995, Ukrainian Nick (Nicolai) Starinski wintered in 1999, and most recently, Seva Kotlyar is wintering in 2022 as the power plant lead.
The first Kiwi men were met observers Barry Porter and Bernie Maguire in 1976, and the first NZ women were carpenters Kate Batten and Vicky Ward in 2005 [(the complete list of 27 **New Zealanders**).](kiwi.html)
The first Australian was Barry Woodberry who came down with the US National Bureau of Standards in 1966. The second Aussie is also notable--Graeme Currie wintered in 1981 (he wintered eleven times at various Australian and other stations)...the first Australian woman was AST/RO observer Jules Harnett in 2004. There have been at least 19 so far who have wintered, most recently including 2021 SPT researcher Matthew Young, 2020 SPT astronomer Geoffrey Chen, as well as 2019 machinist Steele Diggles and power plant mechanic Dennis Calhoun, who is a transplanted US-->Australian citizen [(the list of **Australians**)](aussies.html).
[the South Pole marker installed on 1 January 2011](2010marker.html)
On New Years Day 2011, this amazing marker made its appearance! The first with a finishedwood base and moving parts! An excellent South Pole marker for the centennial year of thefirst visits to this place, long before there was a permanent station! This marker was designedduring the 2010 winter by David Holmes, and created by machinist Derek Aboltins. Here is [therest of the story](2010marker.html) about the marker and the installation ceremony.
Speaking of winterovers from **Sweden**, there now are five--in 2022 sous chef Niko Winegarner is wintering. In 2019 materials person Viktor Barricklow returned (he also wintered in 2017 and has dual Swedish/US citizenship). SPT observer Daniel Michalik, with dual Swedish/German citizenship, wintered in 2017. Earlier, there were IceCube guy Sven Lidström; he wintered in 2007 and was back for 2012 (he also spent several summers at Pole and is currently working for Norway's Antarctic program), and cosray observer Lars Andersson in 1966.
From a bit south of Sweden in the Low Countries, there have been two **Belgians**--Freija Descamps, one of the 2011 IceCube observers, and Jean-Marie Moreau, the 1990 doctor. And Erik Verhagen, with IceCube in 2009, was the first **Netherlands** citizen to winter.
[Noah White](noahwhite1.jpg "Noah at the 2002 OAEA reunion in Pensacola"), radioman/comms guy, wintered three times in 1967, 1970, and 1979. He's the only person to winter both at the original station (Old Pole) and under the dome, the only person to winter both as a Navy man and a civilian, and the first person to winter three times. Yes, I've met him, he was a good guy, sadly, he passed away in early 2019.
1995 and 1996 were interesting winters...1995 was the last year WITH a scheduled midwinter airdrop and WITHOUT internet. They also were the first years when anyone wintered consecutively--Australian astronomer James (Jamie) Lloyd and NOAA science tech Jeff Otten wintered in both 1995 and 1996.
Back to nationalities...it now seems that the first German to winter did so back in the real old days of 1972--gravity geophysicist and German citizen Walter Zürn, who was spending time at UCLA after graduation from Stuttgart. Next was 1983 w/o geophysicist Hans-Albert Dahlheim, who was studying the gravitational pull of the Moon (and won the Round the World Race). Matthias Rumitz (AST/RO) and Robert Schwarz (AMANDA) were next, in 1997. By now there are twenty total...here is [the list of **Germans**](germans.html). As for the **French**, probably the title for the first man goes to the 2006 BICEP researcher Denis Barkats, and 2009 IceCube w/o Camille Parisel is the first woman--she previously spent 14 months at Dumont d'Urville through the 2001 winter. And in 2022, IceCube grantee Celas Marie-Sainte, is also from France. There have been three **Italians**--Moreno Baricevic, one of the 2022 IceCube grantees; the 2018 WSM Marco Tortonese, who also wintered in 2011 as a science tech; and the first Italian was Paolo Calisse, the 2003 VIPER/AASTO winterover. 2010 (and 2011 and 2012) brought Ricardo Lopez, the first Polie originally from the **Dominican Republic**, and 2005 featured the first **Jamaican**, fellow winterover and HR person Kurt Montas.
[the South Pole marker installed on 1 January 2010](2009marker.html)
This unique 2010 marker features the South Pole Telescope along with 43 IceCube DOMs,one for each of the 2009 wo's.It was designed and fabricated by the 2009 SCOARA machinist[Steele Diggles](http://antarcticsun.usap.gov/features/contenthandler.cfm?id=1836 "Antarctic Sun article"). More [information and photos by Forest Banks,](2009marker.html) including the placement ceremonyon New Years Day...
Laser scientist Ashraf El-Dakrouri, who wintered in 2000, was the first **Egyptian** (and the first person from any Arab or Muslim nation) to winter at Pole [(profile article](antsun20000116ashraf.pdf) from the 16 January 2000 *Antarctic Sun*). Hein Van Bui, the 1988 w/o computer tech, was the first person from **Vietnam** to winter. He was followed by Hien Nguyen, the 1994 SPIREX researcher/SSL; and Xuan Ta, the 2004 Title II inspector. There have been four **Chinese** (PRC) citizens to winter: AST/RO astronomer Xiaolei Zhang (1998), AMANDA researcher Xinhua Bai (1999),Kecheng Xiao (AST/RO, 2002), and electrician Hung So (2010).
We've had four people from **India** winter...the first was Roopesh Ojha, a citizen of the Republic of India who wintered with CARA/ASTRO in 1999. Also there with him that year was science tech Reza Mossadeque (of Indian and Bangladeshi origin, although he was an American citizen when he wintered). Next was 2007 w/o Karthik Soundarapandian, another India citizen, who wintered and is currently working with IceCube. More recently, Aman Chokshi wintered in 2022 with SPT.
From the UK I believe we have had fifteen winterovers (which includes a couple of folks with dual NZ/British citizenship), the most recent one wintered in 2021--IceCube researcher Joshua Veitch-Michaelis [(list of **British** citizens)](uk.html). And from an emerald island next to the UK it seems 2010 winter site manager Mel MacMahon claims both Irish and Canadian heritage, and 1990 CUSP associate Richard Collins was an Irish citizen.
From elsewhere in Europe, note that 2012 cook Kate McGrew was the first **Pole** to winter at Pole (!) From a bit south of there, Monique Gerbex, the 2003 work order planner, hailed from **Switzerland**. Speaking of Switzerland, 2023 IceCube winterover Marc Jacquart also hails from there...and not winterover statistics but important to me...one of the GFAs who was with us in 1976-77, the late Dave Pluth, turned up at our 2007 Pole Soul reunion in Boulder to tell us that he'd become a Swiss citizen. Finally, back in the US of A (but not the 50 states), electrician Osvaldo Torres, who wintered in 2004, is from **Puerto Rico**.
[the South Pole marker installed on 1 January 2009](globea1.jpg)
The 1 January 2009 marker seen here was designed and created by the 2008 w/oSCOARA machinist Dave Postler This photo is by Reinhart Piuk. [More on themarker and the New Years Day ceremony](2008marker.html)...
Some station management statistics (these refer to the winter site manager, not the area manager/resident manager position, which was created for the first time for the 1977-78 summer). The year before then, the station manager had, shall I say (since it was I ;-), a bit more to do during the summer: For the 2005 winter--Bill Henriksen was the first person to return for the second time as manager--in 2003 he had the same job (his first winter was as Title II inspector in 2000). In 2006 through 2018 he wintered in McMurdo as the NSF manager. Katie Hess, the 2008 manager, returned to do that again in 2012. Janet Phillips in 1994 was the first female manager. After the McMurdo winfly, all 3 US stations had female management for the first time--Karen Schwall at McM and Ann Peoples at Palmer as well as Janet [(her article about the experience)](90s/janet.html). Oh, Janet went on to manage Palmer Station in 1996. Speaking of Palmer Station...AFAIK the record of the most times as winter site manager anywhere goes to Ken Keenan...his first winter was at Pole with me in 2005, but subsequently he's been the Palmer winter site manager nine times between 2009 and 2022.
Three managers during the civilian era were last-minute replacements--Dan Morton in 1976, Rich Wiik in 1983, and Dennis O'Neill in 1991. Rich and Dennis had been at Pole, scheduled to winter in other positions, but Dan had NOT worked at Pole and was not originally scheduled to winter until 1977. All 3 guys are friends of mine and did well.
[the South Pole marker installed on 1 January 2008](2008polemarker1.jpg)
Here's the marker placed on 1 January 2008, designed by 2007 w/o facilities engineerLaura Rip...and created by SCOARA machinist Derek Aboltins. Photo courtesy GlennGrant (whom I finally got to meet in person!). [More information about the marker andphotos of the ceremony are here](2007marker.html).
Last but not least, some statistics that had nothing to do with Pole until 2014. For a number of years since 2004, power plant mechanic Rocky (Gerald or Gerry) Ness held the all-time record for 15 Antarctic winters--all at Palmer and McMurdo. But in 2014 that record was broken by two people. At McMurdo, George Lampman had his sixteenth CONSECUTIVE winter...all of them at McMurdo, more recently as operations supervisor. He was documented in the film [Antarctica: A Year On Ice](http://frozensouth.weebly.com/). And at Pole, Johan Booth also had his 16th winter in 2016, none of which have been at McMurdo. Both George and Johan had their 17th winters in 2015. Johan had his 18th winter in 2016. but George did not. As of 2016 the undisputed record holder for women was Wendy Kober who had her 15th winter that year. Previously in 2015 Wendy had tied Angela Garner at 14 winters. Angela wintered again in 2017, so the two women Wendy and Angela are still tied at 15 winters.
Back to the men...the person with the most total Antarctic winters is...Rex Cotten! He is wintering at McMurdo in 2023--his 23rd winter, again monitoring the NASA McMurdo Ground Station, a 10-meter antenna which monitors and downloads data from polar-orbiting science satellites...a mission which has gotten much more useful with the availability of the new internet earth station at McMurdo [(more project info from the NSF Science Planning Summary)](https://www.usap.gov/sciencesupport/scienceplanningsummaries/2022_2023/results.cfm?formAction=detail&ID=204). All of his winters are consecutive (I think). At one time, he and the late Johan Booth (alas, Johan passed away from cancer on 29 June 2022 [obituary](20s/johan.html)) were tied for 20 winters. Johan wintered six times at Palmer between 1994 and 2004, and 14 times at Pole between 1995 and 2020. The twists...Rex's winters have all been at McMurdo, while all of Johan's winters have been at Palmer and Pole. All of course in Antarctica, and of course all of Rex's winters have been south of the Antarctic Circle.
Yes, I know, there must be more vital stats--[send em to me!!](../info.html)
[the South Pole marker installed on 1 January 2007](2007polemarker1.jpg)The 2007 Pole marker ([Antarctic photo library](http://photolibrary.usap.gov/), photo by Glenn Grant). The marker was
designed by 2006 (and 2005 :) AND 2004 w/o electrician Clayton Cornia. Yes...onceagain, each dimple represents one of the 64 winterovers.
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| [the Pole marker installed in January 1997](1996marker.html)Okay...as a bit of trivia I must add this bit of information about the 1997 Pole marker, as I get asked about this now and then. A summer visitor acquired a copy of it and later tried to sell it...on an episode of *Pawn Stars* first aired by the History Channel in December 2009. The episode gets aired now and again more recently, and it's also available online...[hence these details](1996marker.html). | [the Pole marker installed in November 1976](1996marker.html)This was the first Pole marker I was ever aware of...some USGS folks showed up to install it in November 1976 to mark the American centennial. Based on the dates, I assumed that they'd planned to show up with it a year earlier, but in 1975-76 flights and visits were severely curtailed because of the 3 LC-130's that had crashed at Dome C. Oh, this marker was stolen less than a day later [(more info from my 1976-77 winterover pages)](../pole/survey.html). | [the very first Pole marker from 1959-60](igy1/firstmarker.html)Above...an image of the very first (and long-lost) South Pole marker, manufactured in Washington DC and hand-carried to the station during the 1959-60 season. It does not say "90º South" as it was not placed at the Pole, but inside the original station, where it presumably still is today. As with the one at left, multiple copies of it have been in play-- most recently, it was up on eBay in January 2016 (it didn't sell). [Here's the rest of that story](igy1/firstmarker.html). |
| Thanks to Katy Jensen, who originally crunched the data to produce many of the statistics you see here. Credits for the photos at the top of the page--the group in the left photo is the 1957 team, note Paul Siple in the back row [(caption and more information)](igy1/1957.html); and the motley crew in the right photo is, of course, [us 1977 Pole Souls](../pole/whoarewe.html) :). The panorama below is [the 2004 w/o picture](00s/2004.html), by Glen Kinoshita.
Another disclaimer...again the nationality statistics seen here are strictly voluntary or from officially published information and include folks who were born and/or are or were citizens of the indicated countries.
a small group of friends |
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<P> I have seen all the movies listed on this site myself and try to review everything I see at the cinema.
<P> Included are the DVD covers for all the movies I could find so they are easier to tell apart and a link to buy each movie in case you are looking for that title to buy. If you are lucky enough to know Cantonese, I have also added the original Cantonese language title of each movie to the index pages and the reviews themselves for easy of reference.
<P> Please click on the first letter of the title to go to that section:<BR>
<A HREF="a_to_c.htm"># - C</A> | <A HREF="d_to_g.htm">D - G</A> | <A HREF="h_to_k.htm">H - K</A> | <A HREF="l_to_o.htm">L - O </A> | <A HREF="p_to_s.htm">P - S</A> | <A HREF="t_to_w.htm">T - W</A> | <A HREF="x_to_z.htm">X - Z</A></p>
<p><a href="http://www.aheroneverdies.com">A Hero Never Dies</a> - a cool movie and a great website, haven't seen a new site on HK movies for ages.</p>
<p><a href="http://hongkongonfilm.blogspot.co.uk/" target="_blank">Hong Kong on Film</a> - Tracking down the locations in Hong Kong film in the real world.</p>
<p><a href="http://www.heroicsisterhood.com/" target="_blank">Heroic Sisterhood</a> - Hong Kong cinema from a woman's perspective. </p>
<p>Podcasts I have been listening to:<br>
<a href="http://podcastonfire.com/" target="_blank">Podcast on Fire</a> - Focussing on Hong Kong and Asian cinema<br>
<a href="http://podcastwithouthonorandhumanity.libsyn.com/" target="_blank">Podcast Without Honour or Humanity</a> - Asian cinema podcast<br>
<a href="http://ggtmc.com/" target="_blank">The Gentlemen's Guide to Midnite Cinema</a> - broad coverage of genre films including Asian cinema. <br>
<a href="http://silvaandgold.com/" target="_blank">Silva and Gold</a>- A wild and wooly podcast on genre cinema.</p>
<P><span class="style2 style3">Special Features: </span><br>
<a href="jttwctd_funnyface.htm">Shu Qi making a funny faces in Journey to the West</a><br>
<a href="godofcookery_animated.htm">God of Cookery animated GIFs </a><br>
<a href="loveondelivery_garfeicat.htm">Gar-Fei Cat - Love on Delivery</a> animated GIFs <br>
<a href="yuenbiaogoesfishing.htm">Yuen Biao goes fishing</a> animated GIFs <br>
<a href="randomhkmovietitlegen.php">Random Hong Kong Movie Title Generator</a><br>
<a href="vcd.htm">VCDs explained</a><BR>
<a href="sirenvisualentertainment.htm">Movies available from Siren Visual Entertainment</a><BR>
<a href="stephenchownosepicking.htm">Nose Picking in Stephen Chow Movies</a> (I can see what you are searching for!) <BR>
<a href="hkmovieskickarse.htm">Hong Kong movies that kick arse!</a> (satire)<BR>
Review of the <a href="scc_periodfantasy.htm">Stephen Chow Collection: Period/Fantasy</a>. <br>
<A HREF="http://track.webgains.com/click.html?wgcampaignid=32723&wgprogramid=1120&wgtarget=http://global.yesasia.com/en/Browse/ProductGroupList.aspx/section-videos/code-c/version-all/pid-1004482939/">Hong Kong movies with CGI effects</A> (link)<BR>
<A HREF="http://track.webgains.com/click.html?wgcampaignid=32723&wgprogramid=1120&wgtarget=http://global.yesasia.com/en/Browse/ProductGroupList.aspx/code-cl/pid-1004482940/sortby-7">Asian Horror</A> (link)<br>
<P> </P>
<P> Email you comments to: <A HREF="mailto:webmaster@timchuma.com">webmaster@timchuma.com</A>
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Tim's Hong Kong Movie Reviews
I have seen all the movies listed on this site myself and try to review everything I see at the cinema.
Included are the DVD covers for all the movies I could find so they are easier to tell apart and a link to buy each movie in case you are looking for that title to buy. If you are lucky enough to know Cantonese, I have also added the original Cantonese language title of each movie to the index pages and the reviews themselves for easy of reference.
Please click on the first letter of the title to go to that section:
[# - C](a_to_c.htm) | [D - G](d_to_g.htm) | [H - K](h_to_k.htm) | [L - O](l_to_o.htm) | [P - S](p_to_s.htm) | [T - W](t_to_w.htm) | [X - Z](x_to_z.htm)
[A Hero Never Dies](http://www.aheroneverdies.com) - a cool movie and a great website, haven't seen a new site on HK movies for ages.
[Hong Kong on Film](http://hongkongonfilm.blogspot.co.uk/) - Tracking down the locations in Hong Kong film in the real world.
[Heroic Sisterhood](http://www.heroicsisterhood.com/) - Hong Kong cinema from a woman's perspective.
Podcasts I have been listening to:
[Podcast on Fire](http://podcastonfire.com/) - Focussing on Hong Kong and Asian cinema
[Podcast Without Honour or Humanity](http://podcastwithouthonorandhumanity.libsyn.com/) - Asian cinema podcast
[The Gentlemen's Guide to Midnite Cinema](http://ggtmc.com/) - broad coverage of genre films including Asian cinema.
[Silva and Gold](http://silvaandgold.com/)- A wild and wooly podcast on genre cinema.
Special Features:
[Shu Qi making a funny faces in Journey to the West](jttwctd_funnyface.htm)
[God of Cookery animated GIFs](godofcookery_animated.htm)
[Gar-Fei Cat - Love on Delivery](loveondelivery_garfeicat.htm) animated GIFs
[Yuen Biao goes fishing](yuenbiaogoesfishing.htm) animated GIFs
[Random Hong Kong Movie Title Generator](randomhkmovietitlegen.php)
[VCDs explained](vcd.htm)
[Movies available from Siren Visual Entertainment](sirenvisualentertainment.htm)
[Nose Picking in Stephen Chow Movies](stephenchownosepicking.htm) (I can see what you are searching for!)
[Hong Kong movies that kick arse!](hkmovieskickarse.htm) (satire)
Review of the [Stephen Chow Collection: Period/Fantasy](scc_periodfantasy.htm).
[Hong Kong movies with CGI effects](http://track.webgains.com/click.html?wgcampaignid=32723&wgprogramid=1120&wgtarget=http://global.yesasia.com/en/Browse/ProductGroupList.aspx/section-videos/code-c/version-all/pid-1004482939/) (link)
[Asian Horror](http://track.webgains.com/click.html?wgcampaignid=32723&wgprogramid=1120&wgtarget=http://global.yesasia.com/en/Browse/ProductGroupList.aspx/code-cl/pid-1004482940/sortby-7) (link)
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<HTML>
<HEADER>
<TITLE>Perlisisms - "Epigrams in Programming" by Alan J. Perlis</TITLE>
</HEADER>
<BODY BGCOLOR="#D0D0FF">
<P>
<CENTER>
<HR SIZE=25>
<P>
<H1>EPIGRAMS IN PROGRAMMING</H1>
<P>
<HR SIZE=25>
<P>
1. One man's constant is another man's variable.
<P>
2. Functions delay binding; data structures induce binding.
Moral: Structure data late in the programming process.
<P>
3. Syntactic sugar causes cancer of the semicolon.
<P>
4. Every program is a part of some other program and rarely
fits.
<P>
5. If a program manipulates a large amount of data, it does
so in a small number of ways.
<P>
6. Symmetry is a complexity-reducing concept (co-routines
include subroutines); seek it everywhere.
<P>
7. It is easier to write an incorrect program than
understand a correct one.
<P>
8. A programming language is low level when its programs
require attention to the irrelevant.
<P>
9. It is better to have 100 functions operate on one data
structure than 10 functions on 10 data structures.
<P>
10. Get into a rut early: Do the same process the same way.
Accumulate idioms. Standardize. The only difference(!)
between Shakespeare and you was the size of his idiom list -
not the size of his vocabulary.
<P>
11. If you have a procedure with ten parameters, you
probably missed some.
<P>
12. Recursion is the root of computation since it trades
description for time.
<P>
13. If two people write exactly the same program, each
should be put into microcode and then they certainly won't
be the same.
<P>
14. In the long run every program becomes rococo - then
rubble.
<P>
15. Everything should be built top-down, except the first
time.
<P>
16. Every program has (at least) two purposes: the one for
which it was written, and another for which it wasn't.
<P>
17. If a listener nods his head when you're explaining your
program, wake him up.
<P>
18. A program without a loop and a structured variable isn't
worth writing.
<P>
19. A language that doesn't affect the way you think about
programming, is not worth knowing.
<P>
20. Wherever there is modularity there is the potential for
misunderstanding: Hiding information implies a need to check
communication.
<P>
21. Optimization hinders evolution.
<P>
22. A good system can't have a weak command language.
<P>
23. To understand a program you must become both the machine
and the program.
<P>
24. Perhaps if we wrote programs from childhood on, as
adults we'd be able to read them.
<P>
25. One can only display complex information in the mind.
Like seeing, movement or flow or alteration of view is more
important than the static picture, no matter how lovely.
<P>
26. There will always be things we wish to say in our
programs that in all known languages can only be said
poorly.
<P>
27. Once you understand how to write a program get someone
else to write it.
<P>
28. Around computers it is difficult to find the correct
unit of time to measure progress. Some cathedrals took a
century to complete. Can you imagine the grandeur and scope
of a program that would take as long?
<P>
29. For systems, the analogue of a face-lift is to add to
the control graph an edge that creates a cycle, not just an
additional node.
<P>
30. In programming, everything we do is a special case of
something more general -- and often we know it too quickly.
<P>
31. Simplicity does not precede complexity, but follows it.
<P>
32. Programmers are not to be measured by their ingenuity
and their logic but by the completeness of their case
analysis.
<P>
33. The eleventh commandment was "Thou Shalt Compute" or
"Thou Shalt Not Compute" - I forget which.
<P>
34. The string is a stark data structure and everywhere it
is passed there is much duplication of process. It is a
perfect vehicle for hiding information.
<P>
35. Everyone can be taught to sculpt: Michelangelo would
have had to be taught not to. So it is with great
programmers.
<P>
36. The use of a program to prove the 4-color theorem will
not change mathematics - it merely demonstrates that the
theorem, a challenge for a century, is probably not
important to mathematics.
<P>
37. The most important computer is the one that rages in our
skulls and ever seeks that satisfactory external emulator.
The standarization of real computers would be a disaster -
and so it probably won't happen.
<P>
38. Structured Programming supports the law of the excluded
middle.
<P>
39. Re graphics: A picture is worth 10K words - but only
those to describe the picture. Hardly any sets of 10K words
can be adequately described with pictures.
<P>
40. There are two ways to write error-free programs; only
the third one works.
<P>
41. Some programming languages manage to absorb change, but
withstand progress.
<P>
42. You can measure a programmer's perspective by noting his
attitude on the continuing vitality of FORTRAN.
<P>
43. In software systems, it is often the early bird that
makes the worm.
<P>
44.Sometimes I think the only universal in the computing
field is the fetch-execute cycle.
<P>
45. The goal of computation is the emulation of our
synthetic abilities, not the understanding of our analytic
ones.
<P>
46. Like punning, programming is a play on words.
<P>
47. As Will Rogers would have said, "There is no such thing
as a free variable."
<P>
48. The best book on programming for the layman is "Alice in
Wonderland"; but that's because it's the best book on
anything for the layman.
<P>
49. Giving up on assembly language was the apple in our
Garden of Eden: Languages whose use squanders machine cycles
are sinful. The LISP machine now permits LISP programmers to
abandon bra and fig-leaf.
<P>
50. When we understand knowledge-based systems, it will be
as before -- except our fingertips will have been singed.
<P>
51. Bringing computers into the home won't change either
one, but may revitalize the corner saloon.
<P>
52. Systems have sub-systems and sub-systems have sub-
systems and so on ad infinitum - which is why we're always
starting over.
<P>
53. So many good ideas are never heard from again once they
embark in a voyage on the semantic gulf.
<P>
54. Beware of the Turing tar-pit in which everything is
possible but nothing of interest is easy.
<P>
55. A LISP programmer knows the value of everything, but the
cost of nothing.
<P>
56. Software is under a constant tension. Being symbolic it
is arbitrarily perfectible; but also it is arbitrarily
changeable.
<P>
57. It is easier to change the specification to fit the
program than vice versa.
<P>
58. Fools ignore complexity. Pragmatists suffer it. Some can
avoid it. Geniuses remove it.
<P>
59. In English every word can be verbed. Would that it were
so in our programming languages.
<P>
60. In seeking the unattainable, simplicity only gets in
the way.
<P>
61. In programming, as in everything else, to be in error is
to be reborn.
<P>
62. In computing, invariants are ephemeral.
<P>
63. When we write programs that "learn", it turns out that
we do and they don't.
<P>
64. Often it is the means that justify the ends: Goals
advance technique and technique survives even when goal
structures crumble.
<P>
65. Make no mistake about it: Computers process numbers -
not symbols. We measure our understanding (and control) by
the extent to which we can arithmetize an activity.
<P>
66. Making something variable is easy. Controlling duration
of constancy is the trick.
<P>
67. Think of all the psychic energy expended in seeking a
fundamental distinction between "algorithm" and "program".
<P>
68. If we believe in data structures, we must believe in
independent (hence simultaneous) processing. For why else
would we collect items within a structure? Why do we
tolerate languages that give us the one without the other?
<P>
69. In a 5 year period we get one superb programming
language. Only we can't control when the 5 year period will
be.
<P>
70. Over the centuries the Indians developed sign language
for communicating phenomena of interest. Programmers from
different tribes (FORTRAN, LISP, ALGOL, SNOBOL, etc.) could
use one that doesn't require them to carry a blackboard on
their ponies.
<P>
71. Documentation is like term insurance: It satisfies
because almost no one who subscribes to it depends on its
benefits.
<P>
72. An adequate bootstrap is a contradiction in terms.
<P>
73. It is not a language's weakness but its strengths that
control the gradient of its change: Alas, a language never
escapes its embryonic sac.
<P>
74. Is it possible that software is not like anything else,
that it is meant to be discarded: that the whole point is to
see it as a soap bubble?
<P>
75. Because of its vitality, the computing field is always
in desperate need of new cliches: Banality soothes our
nerves.
<P>
76. It is the user who should parameterize procedures, not
their creators.
<P>
77. The cybernetic exchange between man, computer and
algorithm is like a game of musical chairs: The frantic
search for balance always leaves one of the three standing
ill at ease.
<P>
78. If your computer speaks English, it was probably made in
Japan.
<P>
79. A year spent in artificial intelligence is enough to
make one believe in God.
<P>
80. Prolonged contact with the computer turns mathematicians
into clerks and vice versa.
<P>
81. In computing, turning the obvious into the useful is a
living definition of the word "frustration".
<P>
82. We are on the verge: Today our program proved Fermat's
next-to-last theorem.
<P>
83. What is the difference between a Turing machine and the
modern computer? It's the same as that between Hillary's
ascent of Everest and the establishment of a Hilton hotel on
its peak.
<P>
84. Motto for a research laboratory: What we work on today,
others will first think of tomorrow.
<P>
85. Though the Chinese should adore APL, it's FORTRAN they
put their money on.
<P>
86. We kid ourselves if we think that the ratio of procedure
to data in an active data-base system can be made
arbitrarily small or even kept small.
<P>
87. We have the mini and the micro computer. In what
semantic niche would the pico computer fall?
<P>
88. It is not the computer's fault that Maxwell's equations
are not adequate to design the electric motor.
<P>
89. One does not learn computing by using a hand calculator,
but one can forget arithmetic.
<P>
90. Computation has made the tree flower.
<P>
91. The computer reminds one of Lon Chaney -- it is the
machine of a thousand faces.
<P>
92. The computer is the ultimate polluter: its feces are
indistinguish- able from the food it produces.
<P>
93. When someone says "I want a programming language in
which I need only say what I wish done," give him a
lollipop.
<P>
94. Interfaces keep things tidy, but don't accelerate
growth: Functions do.
<P>
95. Don't have good ideas if you aren't willing to be
responsible for them.
<P>
96. Computers don't introduce order anywhere as much as they
expose opportunities.
<P>
97. When a professor insists computer science is X but not
Y, have compassion for his graduate students.
<P>
98. In computing, the mean time to failure keeps getting
shorter.
<P>
99. In man-machine symbiosis, it is man who must adjust: The
machines can't.
<P>
100. We will never run out of things to program as long as
there is a single program around.
<P>
101. Dealing with failure is easy: Work hard to improve.
Success is also easy to handle: You've solved the wrong
problem. Work hard to improve.
<P>
102. One can't proceed from the informal to the formal by
formal means.
<P>
103. Purely applicative languages are poorly applicable.
<P>
104. The proof of a system's value is its existence.
<P>
105. You can't communicate complexity, only an awareness of
it.
<P>
106. It's difficult to extract sense from strings, but
they're the only communication coin we can count on.
<P>
107. The debate rages on: is PL/I Bachtrian or Dromedary?
<P>
108. Whenever two programmers meet to criticize their
programs, both are silent.
<P>
109. Think of it! With VLSI we can pack 100 ENIACS in 1 sq.
cm.
<P>
110. Editing is a rewording activity.
<P>
111. Why did the Roman Empire collapse? What is Latin for
office automation?
<P>
112. Computer Science is embarrassed by the computer.
<P>
113. The only constructive theory connecting neuroscience
and psychology will arise from the study of software.
<P>
114. Within a computer natural language is unnatural.
<P>
115. Most people find the concept of programming obvious,
but the doing impossible.
<P>
116. You think you know when you can learn, are more sure
when you can write, even more when you can teach, but
certain when you can program.
<P>
117. It goes against the grain of modern education to teach
children to program. What fun is there in making plans,
acquiring discipline in organizing thoughts, devoting
attention to detail and learning to be self-critical?
<P>
118. If you can imagine a society in which the computer-
robot is the only menial, you can imagine anything.
<P>
119. Programming is an unnatural act.
<P>
120. Adapting old programs to fit new machines usually means
adapting new machines to behave like old ones.
<P>
</CENTER>
<P>
<HR SIZE=10>
<P>
<H6>
From ACM's SIGPLAN publication, (September, 1982), Article "Epigrams in
Programming", by Alan J. Perlis of Yale University.
</H6>
</BODY>
<HTML>
|
Perlisisms - "Epigrams in Programming" by Alan J. Perlis
---
# EPIGRAMS IN PROGRAMMING
---
1. One man's constant is another man's variable.
2. Functions delay binding; data structures induce binding.
Moral: Structure data late in the programming process.
3. Syntactic sugar causes cancer of the semicolon.
4. Every program is a part of some other program and rarely
fits.
5. If a program manipulates a large amount of data, it does
so in a small number of ways.
6. Symmetry is a complexity-reducing concept (co-routines
include subroutines); seek it everywhere.
7. It is easier to write an incorrect program than
understand a correct one.
8. A programming language is low level when its programs
require attention to the irrelevant.
9. It is better to have 100 functions operate on one data
structure than 10 functions on 10 data structures.
10. Get into a rut early: Do the same process the same way.
Accumulate idioms. Standardize. The only difference(!)
between Shakespeare and you was the size of his idiom list -
not the size of his vocabulary.
11. If you have a procedure with ten parameters, you
probably missed some.
12. Recursion is the root of computation since it trades
description for time.
13. If two people write exactly the same program, each
should be put into microcode and then they certainly won't
be the same.
14. In the long run every program becomes rococo - then
rubble.
15. Everything should be built top-down, except the first
time.
16. Every program has (at least) two purposes: the one for
which it was written, and another for which it wasn't.
17. If a listener nods his head when you're explaining your
program, wake him up.
18. A program without a loop and a structured variable isn't
worth writing.
19. A language that doesn't affect the way you think about
programming, is not worth knowing.
20. Wherever there is modularity there is the potential for
misunderstanding: Hiding information implies a need to check
communication.
21. Optimization hinders evolution.
22. A good system can't have a weak command language.
23. To understand a program you must become both the machine
and the program.
24. Perhaps if we wrote programs from childhood on, as
adults we'd be able to read them.
25. One can only display complex information in the mind.
Like seeing, movement or flow or alteration of view is more
important than the static picture, no matter how lovely.
26. There will always be things we wish to say in our
programs that in all known languages can only be said
poorly.
27. Once you understand how to write a program get someone
else to write it.
28. Around computers it is difficult to find the correct
unit of time to measure progress. Some cathedrals took a
century to complete. Can you imagine the grandeur and scope
of a program that would take as long?
29. For systems, the analogue of a face-lift is to add to
the control graph an edge that creates a cycle, not just an
additional node.
30. In programming, everything we do is a special case of
something more general -- and often we know it too quickly.
31. Simplicity does not precede complexity, but follows it.
32. Programmers are not to be measured by their ingenuity
and their logic but by the completeness of their case
analysis.
33. The eleventh commandment was "Thou Shalt Compute" or
"Thou Shalt Not Compute" - I forget which.
34. The string is a stark data structure and everywhere it
is passed there is much duplication of process. It is a
perfect vehicle for hiding information.
35. Everyone can be taught to sculpt: Michelangelo would
have had to be taught not to. So it is with great
programmers.
36. The use of a program to prove the 4-color theorem will
not change mathematics - it merely demonstrates that the
theorem, a challenge for a century, is probably not
important to mathematics.
37. The most important computer is the one that rages in our
skulls and ever seeks that satisfactory external emulator.
The standarization of real computers would be a disaster -
and so it probably won't happen.
38. Structured Programming supports the law of the excluded
middle.
39. Re graphics: A picture is worth 10K words - but only
those to describe the picture. Hardly any sets of 10K words
can be adequately described with pictures.
40. There are two ways to write error-free programs; only
the third one works.
41. Some programming languages manage to absorb change, but
withstand progress.
42. You can measure a programmer's perspective by noting his
attitude on the continuing vitality of FORTRAN.
43. In software systems, it is often the early bird that
makes the worm.
44.Sometimes I think the only universal in the computing
field is the fetch-execute cycle.
45. The goal of computation is the emulation of our
synthetic abilities, not the understanding of our analytic
ones.
46. Like punning, programming is a play on words.
47. As Will Rogers would have said, "There is no such thing
as a free variable."
48. The best book on programming for the layman is "Alice in
Wonderland"; but that's because it's the best book on
anything for the layman.
49. Giving up on assembly language was the apple in our
Garden of Eden: Languages whose use squanders machine cycles
are sinful. The LISP machine now permits LISP programmers to
abandon bra and fig-leaf.
50. When we understand knowledge-based systems, it will be
as before -- except our fingertips will have been singed.
51. Bringing computers into the home won't change either
one, but may revitalize the corner saloon.
52. Systems have sub-systems and sub-systems have sub-
systems and so on ad infinitum - which is why we're always
starting over.
53. So many good ideas are never heard from again once they
embark in a voyage on the semantic gulf.
54. Beware of the Turing tar-pit in which everything is
possible but nothing of interest is easy.
55. A LISP programmer knows the value of everything, but the
cost of nothing.
56. Software is under a constant tension. Being symbolic it
is arbitrarily perfectible; but also it is arbitrarily
changeable.
57. It is easier to change the specification to fit the
program than vice versa.
58. Fools ignore complexity. Pragmatists suffer it. Some can
avoid it. Geniuses remove it.
59. In English every word can be verbed. Would that it were
so in our programming languages.
60. In seeking the unattainable, simplicity only gets in
the way.
61. In programming, as in everything else, to be in error is
to be reborn.
62. In computing, invariants are ephemeral.
63. When we write programs that "learn", it turns out that
we do and they don't.
64. Often it is the means that justify the ends: Goals
advance technique and technique survives even when goal
structures crumble.
65. Make no mistake about it: Computers process numbers -
not symbols. We measure our understanding (and control) by
the extent to which we can arithmetize an activity.
66. Making something variable is easy. Controlling duration
of constancy is the trick.
67. Think of all the psychic energy expended in seeking a
fundamental distinction between "algorithm" and "program".
68. If we believe in data structures, we must believe in
independent (hence simultaneous) processing. For why else
would we collect items within a structure? Why do we
tolerate languages that give us the one without the other?
69. In a 5 year period we get one superb programming
language. Only we can't control when the 5 year period will
be.
70. Over the centuries the Indians developed sign language
for communicating phenomena of interest. Programmers from
different tribes (FORTRAN, LISP, ALGOL, SNOBOL, etc.) could
use one that doesn't require them to carry a blackboard on
their ponies.
71. Documentation is like term insurance: It satisfies
because almost no one who subscribes to it depends on its
benefits.
72. An adequate bootstrap is a contradiction in terms.
73. It is not a language's weakness but its strengths that
control the gradient of its change: Alas, a language never
escapes its embryonic sac.
74. Is it possible that software is not like anything else,
that it is meant to be discarded: that the whole point is to
see it as a soap bubble?
75. Because of its vitality, the computing field is always
in desperate need of new cliches: Banality soothes our
nerves.
76. It is the user who should parameterize procedures, not
their creators.
77. The cybernetic exchange between man, computer and
algorithm is like a game of musical chairs: The frantic
search for balance always leaves one of the three standing
ill at ease.
78. If your computer speaks English, it was probably made in
Japan.
79. A year spent in artificial intelligence is enough to
make one believe in God.
80. Prolonged contact with the computer turns mathematicians
into clerks and vice versa.
81. In computing, turning the obvious into the useful is a
living definition of the word "frustration".
82. We are on the verge: Today our program proved Fermat's
next-to-last theorem.
83. What is the difference between a Turing machine and the
modern computer? It's the same as that between Hillary's
ascent of Everest and the establishment of a Hilton hotel on
its peak.
84. Motto for a research laboratory: What we work on today,
others will first think of tomorrow.
85. Though the Chinese should adore APL, it's FORTRAN they
put their money on.
86. We kid ourselves if we think that the ratio of procedure
to data in an active data-base system can be made
arbitrarily small or even kept small.
87. We have the mini and the micro computer. In what
semantic niche would the pico computer fall?
88. It is not the computer's fault that Maxwell's equations
are not adequate to design the electric motor.
89. One does not learn computing by using a hand calculator,
but one can forget arithmetic.
90. Computation has made the tree flower.
91. The computer reminds one of Lon Chaney -- it is the
machine of a thousand faces.
92. The computer is the ultimate polluter: its feces are
indistinguish- able from the food it produces.
93. When someone says "I want a programming language in
which I need only say what I wish done," give him a
lollipop.
94. Interfaces keep things tidy, but don't accelerate
growth: Functions do.
95. Don't have good ideas if you aren't willing to be
responsible for them.
96. Computers don't introduce order anywhere as much as they
expose opportunities.
97. When a professor insists computer science is X but not
Y, have compassion for his graduate students.
98. In computing, the mean time to failure keeps getting
shorter.
99. In man-machine symbiosis, it is man who must adjust: The
machines can't.
100. We will never run out of things to program as long as
there is a single program around.
101. Dealing with failure is easy: Work hard to improve.
Success is also easy to handle: You've solved the wrong
problem. Work hard to improve.
102. One can't proceed from the informal to the formal by
formal means.
103. Purely applicative languages are poorly applicable.
104. The proof of a system's value is its existence.
105. You can't communicate complexity, only an awareness of
it.
106. It's difficult to extract sense from strings, but
they're the only communication coin we can count on.
107. The debate rages on: is PL/I Bachtrian or Dromedary?
108. Whenever two programmers meet to criticize their
programs, both are silent.
109. Think of it! With VLSI we can pack 100 ENIACS in 1 sq.
cm.
110. Editing is a rewording activity.
111. Why did the Roman Empire collapse? What is Latin for
office automation?
112. Computer Science is embarrassed by the computer.
113. The only constructive theory connecting neuroscience
and psychology will arise from the study of software.
114. Within a computer natural language is unnatural.
115. Most people find the concept of programming obvious,
but the doing impossible.
116. You think you know when you can learn, are more sure
when you can write, even more when you can teach, but
certain when you can program.
117. It goes against the grain of modern education to teach
children to program. What fun is there in making plans,
acquiring discipline in organizing thoughts, devoting
attention to detail and learning to be self-critical?
118. If you can imagine a society in which the computer-
robot is the only menial, you can imagine anything.
119. Programming is an unnatural act.
120. Adapting old programs to fit new machines usually means
adapting new machines to behave like old ones.
---
######
From ACM's SIGPLAN publication, (September, 1982), Article "Epigrams in
Programming", by Alan J. Perlis of Yale University.
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<img src="afish.jpg" o:title="fish"/>
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<br>
Heres some links:<br>
<br><a href="new.htm">my new tank</a></br>
<br><a href="later.htm">a few months later</a></br>
<br><a href="howto.htm">Quick Getting Started Guide to Aquariums</a></br>
<br><a href="diy.htm">DIY $10 Overflow Box</a></br><br><br></b>
<a href="../"><b>back</b></a></body></div>
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Chris' Aquarium Page
**# Welcome to Chris' aquarium page.
![](afish.jpg)
Heres some links:
[my new tank](new.htm)
[a few months later](later.htm)
[Quick Getting Started Guide to Aquariums](howto.htm)
[DIY $10 Overflow Box](diy.htm)**
[**back**](../)
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Sarah's Web Page
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Sarah's Web Page<br>
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Welcome and Congrats! You've managed to find my web page, good on ya!<br>
Go ahead and have a look at what I did during my semester in Australia. It was a blast!<br>
Also, check out some of my college photos--they're a riot!<br>
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<br>
This is Ayer's Rock. It's only one of the many places we went on our <a href="australia.html">Tour of Australia</a>. What an incredible country!!<br><br><br>
</td><td width= 50% valign=center align=center>
Playing dress up. <a href="college.html">Dorm life</a> at the University of Iowa was never dull...
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Here are a few snap shots of <a href="nz.html">New Zealand</a>. The country is picture perfect!<br>
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These are my parents. Click here to see more pictures of my <a href="fandf.html">friends and family</a><br>
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<br><br>
<center><font size=4>Interested in seeing more pictures? Try looking here:</font>
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<a href="australia.html">Australia</a>
<br><br>
<a href="college.html">College Life at the University of Iowa</a>
<br><br>
<a href="nz.html">New Zealand</a>
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<a href="fandf.html">Friends and Family</a>
<br><br>
<a href="links.html">My Favorite, Useless Links</a>
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Questions? Comments? Recipes?<br>
<a href="mailto:sarahkarlen@hotmail.com">sarahkarlen@hotmail.com<br></a><br>
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Sarah's Web Page
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Sarah's Web Page
| |
| --- |
| |
Welcome and Congrats! You've managed to find my web page, good on ya!
Go ahead and have a look at what I did during my semester in Australia. It was a blast!
Also, check out some of my college photos--they're a riot! |
| | |
| --- | --- |
|
|
|
|
This is Ayer's Rock. It's only one of the many places we went on our [Tour of Australia](australia.html). What an incredible country!! |
Playing dress up. [Dorm life](college.html) at the University of Iowa was never dull...
|
|
|
|
|
Here are a few snap shots of [New Zealand](nz.html). The country is picture perfect! |
These are my parents. Click here to see more pictures of my [friends and family](fandf.html) |
![](img1.gif)
Interested in seeing more pictures? Try looking here:
[Australia](australia.html)
[College Life at the University of Iowa](college.html)
[New Zealand](nz.html)
[Friends and Family](fandf.html)
[My Favorite, Useless Links](links.html)
![](img1.gif)
Questions? Comments? Recipes?
[sarahkarlen@hotmail.com](mailto:sarahkarlen@hotmail.com)
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<HTML><HEAD><title>URBEX</title>
<meta name="keywords" content="grotty derelict urban decay poo wee" />
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<h1>URBEX</h1><h3>Welcome to my urban exploring pages.</h3><br />
<img src="../fr.png" class="banner" width="100%" height="12" /><table style="width:100%;"><tr><td>
<h2>MY BEST URBEXes</h2>
<h4>Here are my faviorite urban explores. These were very risky.</h4>
<a href="crane.html" class="aaa">Crane climbing</a><br />
<a href="nightsite.html" class="aaa">Night time building site fun</a><br />
<a href="sundaysite.html" class="aaa">Sunday building site fun</a><br />
<a href="infiltration.html" class="aaa">Live building Infiltration</a><br />
<a href="roof.html" class="aaa">Roofing buildings</a><br />
<img src="../fr.png" class="banner" width="100%" height="12" /><table style="width:100%;"><tr><td>
<h2>URBEX ABROAD</h2>
<a href="lithuania.html" class="aaa">Lithuania</a><br />
<img src="../fr.png" class="banner" width="100%" height="12" /><table style="width:100%;"><tr><td>
<h2>GROTTY TRASHED ABANDONED PLACES URBEX</h2>
<h4>Here you will find my favourite run down, abandoned, grim, forgotten and neglected buildings.</h4>
<h4>These buildings have been abandoned a long time and are completly trashed..</h4>
<a href="matthews.html" class="aaa">Matthews Equestrian center (Gillingham)</a><br />
<a href="dovercarpark.html" class="aaa">Car park in Dover</a><br />
<a href="railway.html" class="aaa">Abandoned parts of the UK's railways</a><br />
</td><td style="text-align: right;"><img src="m4.jpg" style="text-align: right;" /></td></tr></table>
<img src="../fr.png" class="banner" width="100%" height="12" /><table style="width:100%;"><tr><td>
<h2>NON-ABANDONED GROTTY PLACES</h2>
<h4>I am interested in grotty places because they are grotty and forgotten about, and they make a nice change to the increasingly amount of boring places there is nowadays.</h4>
<h4>People often talk about pulling these building down or refurbishing them, but I don't want this as I like these places because they are grotty.</h4>
<h4>(I don't just like grotty, I also like ultra modern places, but most modern places are not ultra modern - they are just rather dull)</h4>
<a href="gravesendpier.html" class="aaa">Gravesend ferry pier</a><br />
</td><td style="text-align: right;"><img src="m2.jpg" style="text-align: right;" /></td></tr></table>
<img src="../fr.png" class="banner" width="100%" height="12" /><table style="width:100%;"><tr><td>
<h2>OTHER URBEX</h2>
COMING SOON!
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<img src="../fr.png" class="banner" width="100%" height="12" /><table style="width:100%;"><tr><td>
<h2>PAST PLACES</h2>
<h4>Lastly, here are some places that have either been demolished, or are no longer grotty.</h4>
<a href="chathamtesco.html" class="aaa">Tesco in Chatham (unknown fate)</a><br />
<a href="chathamtrafalgarcentre.html" class="aaa">Chatham Trafalgar Centre (closed down)</a><br />
<a href="gillinghampetrol.html" class="aaa">Abandoned petrol station in Gillingham (now demolished)</a><br />
<a href="pemburyhospital.html" class="aaa">Old Pembury hospital (now demolished)</a><br />
<a href="folkestone.html" class="aaa">Folkestone harbour</a><br />
<a href="chathambusstation.html" class="aaa">Chatham Pentagon bus station</a><br />
</td><td style="text-align: right;"><img src="m6.jpg" style="text-align: right;" /></td></tr></table>
<img src="../fr.png" class="banner" width="100%" height="12" /><table style="width:100%;"><tr><td>
<h1>MEDWAYS FORTS</h1>
<h3>There are LOADS of abandoned forts in Medway and the surrounding area. These were all built from different dates, these range from hundreds of years ago to the the Cold war (1960s). It is amazing how many abandoned forts there are in this area.</h3>
<h4>RANT: One word I absolutely hate is "restoration". What makes these abandoned places so special is that they haven't been over restored. When people talk about restoring places, they say that they are turning them back to how they used to be. THEY ARE NOT. What they are actually doing is turning them into horrid museum theme parks. I HATE so called 'historic buildings' where the building has been converted into a modern tourist experience. Like some twat has just tried to a make it look historic to attracted tourists, but have taken away the building's character.</h4>
<h4>What I like about these forts is that they have NOT been over restored. Some of them have been turned into tourist attractions, but most of them are abandoned</h4>
<a href="https://beno.uk/forts" class="aaa">CLICK HERE FOR MY PAGE ABOUT MEDWAY's FORTS</a><br />
</td><td style="text-align: right;"><img src="m5.jpg" style="text-align: right;" /></td></tr></table>
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URBEX
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# URBEX
### Welcome to my urban exploring pages.
![](../fr.png)
| | | | | | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| MY BEST URBEXes
Here are my faviorite urban explores. These were very risky.
[Crane climbing](crane.html)
[Night time building site fun](nightsite.html)
[Sunday building site fun](sundaysite.html)
[Live building Infiltration](infiltration.html)
[Roofing buildings](roof.html)
| | | | | | | | | | | |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| URBEX ABROAD
[Lithuania](lithuania.html)
| | |
| --- | --- |
| GROTTY TRASHED ABANDONED PLACES URBEX
Here you will find my favourite run down, abandoned, grim, forgotten and neglected buildings.
These buildings have been abandoned a long time and are completly trashed..
[Matthews Equestrian center (Gillingham)](matthews.html)
[Car park in Dover](dovercarpark.html)
[Abandoned parts of the UK's railways](railway.html) | |
| | |
| --- | --- |
| NON-ABANDONED GROTTY PLACES
I am interested in grotty places because they are grotty and forgotten about, and they make a nice change to the increasingly amount of boring places there is nowadays.
People often talk about pulling these building down or refurbishing them, but I don't want this as I like these places because they are grotty.
(I don't just like grotty, I also like ultra modern places, but most modern places are not ultra modern - they are just rather dull)
[Gravesend ferry pier](gravesendpier.html) | |
| | |
| --- | --- |
| OTHER URBEX
COMING SOON!
| |
| | |
| --- | --- |
| PAST PLACES
Lastly, here are some places that have either been demolished, or are no longer grotty.
[Tesco in Chatham (unknown fate)](chathamtesco.html)
[Chatham Trafalgar Centre (closed down)](chathamtrafalgarcentre.html)
[Abandoned petrol station in Gillingham (now demolished)](gillinghampetrol.html)
[Old Pembury hospital (now demolished)](pemburyhospital.html)
[Folkestone harbour](folkestone.html)
[Chatham Pentagon bus station](chathambusstation.html) | |
| | |
| --- | --- |
| MEDWAYS FORTS
There are LOADS of abandoned forts in Medway and the surrounding area. These were all built from different dates, these range from hundreds of years ago to the the Cold war (1960s). It is amazing how many abandoned forts there are in this area.
RANT: One word I absolutely hate is "restoration". What makes these abandoned places so special is that they haven't been over restored. When people talk about restoring places, they say that they are turning them back to how they used to be. THEY ARE NOT. What they are actually doing is turning them into horrid museum theme parks. I HATE so called 'historic buildings' where the building has been converted into a modern tourist experience. Like some twat has just tried to a make it look historic to attracted tourists, but have taken away the building's character.
What I like about these forts is that they have NOT been over restored. Some of them have been turned into tourist attractions, but most of them are abandoned
[CLICK HERE FOR MY PAGE ABOUT MEDWAY's FORTS](https://beno.uk/forts) | |
[Click here to go to the home page](https://beno.uk/) |
|
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<title>Winners of the Nobel Prize in Chemistry</title>
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<h2>Nobel Prize in Chemistry Winners 2022-1901</h2>
(<a href="alpha.html">also available in alphabetical arrangement</a>)
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<h5>brought to you by</h5>
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<!--2022-->
<B><TT><FONT SIZE=+3><a href="/nobel/2022-prizes.html">2022</a></FONT></TT></B>
<P>
The prize was awarded to: <p>
<STRONG>C<font size=-1>AROLYN</font> R. B<font size=-1>ERTOZZI</font></strong>,
<STRONG>M<font size=-1>ORTEN</font> M<font size=-1>ELDAL</font></strong>,
and
<STRONG>K. B<font size=-1>ARRY</font> S<font size=-1>HARPLESS</font></strong>
for the development of click chemistry and bioorthogonal chemistry
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<B><TT><FONT SIZE=+3><a href="/nobel/2021-prizes.html">2021</a></FONT></TT></B>
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The prize was awarded jointly to: <p>
<STRONG>B<font size=-1>ENJAMIN</font> L<font size=-1>IST</font></strong>,
and
<STRONG>D<font size=-1>AVID</font> W. C. M<font size=-1>AC</font>M<font size=-1>ILLAN</font></strong>
for the development of asymmetric organocatalysis.
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<B><TT><FONT SIZE=+3><a href="/nobel/2020-prizes.html">2020</a></FONT></TT></B>
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The prize was awarded to: <p>
<STRONG>E<font size=-1>MMANUELLE</font> C<font size=-1>HARPENTIER</font></strong>,
and
<STRONG>J<font size=-1>ENNIFER</font> A. D<font size=-1>OUDNA</font></strong>
for the development of a method for genome editing.
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<!--2019-->
<B><TT><FONT SIZE=+3><a href="/nobel/2019-prizes.html">2019</a></FONT></TT></B>
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The prize was awarded to: <p>
<STRONG>J<font size=-1>OHN</font> G<font size=-1>OODENOUGH</font></strong>,
<STRONG>M. S<font size=-1>TANLEY</font> W<font size=-1>HITTINGHAM</font> </strong>,
and
<STRONG>A<font size=-1>KIRA</font> Y<font size=-1>OSHINO</font></strong>
for the development of lithium-ion batteries
<p>
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<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2018-->
<B><TT><FONT SIZE=+3><a href="/nobel/2018-prizes.html">2018</a></FONT></TT></B>
<P>
The prize was awarded with one half to: <p>
<STRONG>F<font size=-1>RANCES</font> H. A<font size=-1>RNOLD</font></strong>,
for the directed evolution of enzymes
<p>
and the other half jointly to:<p>
<STRONG>G<font size=-1>EORGE</font> P. S<font size=-1>MITH</font> </strong>,
and
<STRONG>S<font size=-1>IR</font> G<font size=-1>REGORY</font> P. W<font size=-1>INTER</font></strong>
for the phage display of peptides and antibodies
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2017-->
<B><TT><FONT SIZE=+3><a href="/nobel/2017-prizes.html">2017</a></FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<STRONG>J<font size=-1>ACQUES</font> D<font size=-1>UBOCHET</font></strong>,
<STRONG>J<font size=-1>OACHIM</font> F<font size=-1>RANK</font> </strong>,
and
<STRONG>R<font size=-1>ICHRD</font> H<font size=-1>ENDERSON</font></strong>
for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2016-->
<B><TT><FONT SIZE=+3><a href="/nobel/2016-prizes.html">2016</a></FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="2016a.html"><STRONG>J<font size=-1>EAN</font>-P<font size=-1>IERRE</font> S<font size=-1>AUVAGE</font></strong></a>,
<a href="2016b.html"><STRONG>S<font size=-1>IR</font> J. F<font size=-1>RASER</font> S<font size=-1>TODDART</font></strong></a>,
and
<a href="2016c.html"><STRONG>B<font size=-1>ERNARD</font> L. F<font size=-1>ERINGA</font></strong></a>
for the design and synthesis of molecular machines.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2015-->
<B><TT><FONT SIZE=+3><a href="/nobel/2015-prizes.html">2015</a></FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<STRONG>T<font size=-1>OMAS</font> L<font size=-1>INDAHL</font></strong>,
<STRONG>P<font size=-1>AUL</font> M<font size=-1>ODRICH</font></strong>,
and
<STRONG>A<font size=-1>ZIZ</font> S<font size=-1>ANCAR</font></strong>
for mechanistic studies of DNA repair.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2014-->
<B><TT><FONT SIZE=+3><a href="/nobel/2014-prizes.html">2014</a></FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<STRONG>E<font size=-1>RIC</font> B<font size=-1>ETZIG</font></strong>,
<STRONG>S<font size=-1>TEFAN</font> W. H<font size=-1>ELL</font></strong>,
and
<STRONG>W<font size=-1>ILLIAM</font> E. M<font size=-1>OERNER</font></strong>
for the development of super-resolved fluorescence microscopy.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2013-->
<B><TT><FONT SIZE=+3><a href="/nobel/2013-prizes.html">2013</a></FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="2013a.html"><STRONG>M<font size=-1>ARTIN</font> K<font size=-1>ARPLUS</font></strong></a>,
<a href="2013b.html"><STRONG>M<font size=-1>ICHAEL</font> L<font size=-1>EVITT</font></strong></a>,
and
<a href="2013c.html"><STRONG>A<font size=-1>RIEH</font> W<font size=-1>ARSHEL</font></strong></a>
for the development of multiscale models for complex chemical systems.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2012-->
<B><TT><FONT SIZE=+3><a href="/nobel/2012-prizes.html">2012</a></FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="2012a.html"><STRONG>R<font size=-1>OBERT</font> J. L<font size=-1>EFKOWITZ</font></strong></a>
and
<a href="2012b.html"><STRONG>B<font size=-1>RIAN</font> K. K<font size=-1>OBILKA</font></strong></a>
for studies of G-protein-coupled receptors.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2011-->
<B><TT><FONT SIZE=+3><a href="/nobel/2011-prizes.html">2011</a></FONT></TT></B>
<P>
The prize was awarded to: <p>
<a href="2011a.html"><STRONG>D<font size=-1>ANIEL</font> S<font size=-1>HECHTMAN</font></strong></a>
for the discovery of quasicrystals.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2010-->
<B><TT><FONT SIZE=+3><a href="/nobel/2010-prizes.html">2010</a></FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="2010a.html"><STRONG>R<font size=-1>ICHARD</font> F. H<font size=-1>ECK</font></strong></a>,
<a href="2010b.html"><STRONG>E<font size=-1>I-ICHI</font> N<font size=-1>EGISHI</font></strong></a>,
and
<a href="2010c.html"><STRONG>A<font size=-1>KIRA</font> S<font size=-1>UZUKI</font></strong></a>
for palladium-catalyzed cross couplings in organic synthesis.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2009-->
<B><TT><FONT SIZE=+3><a href="/nobel/2009-prizes.html">2009</a></FONT></TT></B>
<P>
The prize goes to: <p>
<a href="2009a.html"><STRONG>V<font size=-1>ENKATRAMAN</font> R<font size=-1>AMAKRISHNAN</font></strong></a>,
<a href="2009b.html"><STRONG>T<font size=-1>HOMAS</font> A. S<font size=-1>TEITZ</font></strong></a>,
and
<a href="2009c.html"><STRONG>A<font size=-1>DA</font> E. Y<font size=-1>ONATH</font></strong></a> for studies of the structure and function of the ribosome.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2008-->
<B><TT><FONT SIZE=+3><a href="/nobel/2008-prizes.html">2008</a></FONT></TT></B>
<P>
The prize goes to: <p>
<a href="2008a.html"><STRONG>O<font size=-1>SAMU</font> S<font size=-1>HIMOMURA</font></strong></a>,
<a href="2008b.html"><STRONG>M<font size=-1>ARTIN</font> C<font size=-1>HALFIE</font></strong></a>,
and
<a href="2008c.html"><STRONG>R<font size=-1>OGER</font> Y T<font size=-1>SIEN</font></strong></a> for the discovery and development of the green fluorescent protein, GFP.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2007-->
<B><TT><FONT SIZE=+3><a href="/nobel/2007-prizes.html">2007</a></FONT></TT></B>
<P>
The prize goes to: <p>
<a href="2007a.html">
<STRONG>G<font size=-1>ERHARD</font> E<font size=-1>RTL</font></strong></a> for his studies of chemical processes on solid surfaces.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2006-->
<B><TT><FONT SIZE=+3><a href="/nobel/2006-prizes.html">2006</a></FONT></TT></B>
<P>
The prize goes to: <p>
<a href="2006a.html">
<STRONG>R<font size=-1>OGER</font> D. K<font size=-1>ORNBERG</font></strong></a> for his studies of the molecular basis of eukaryotic transcription.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2005-->
<B><TT><FONT SIZE=+3><a href="/nobel/2005-prizes.html">2005</a></FONT></TT></B>
<P>
The prize is being awarded jointly to: <p>
<a href="2005a.html">
<STRONG>Y<font size=-1>VES</font> C<font size=-1>HAUVIN</font></strong></a>,
<a href="2005b.html">
<STRONG>R<font size=-1>OBERT</font> H. G<font size=-1>RUBBS</FONT></strong>
</a>,
and
<a href="2005c.html"><STRONG>R<font size=-1>ICHARD</font> R. S<font size=-1>CHROCK</font></strong></a>
for the development of the metathesis method in organic synthesis.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2004-->
<B><TT><FONT SIZE=+3><a href="/nobel/2004-prizes.html">2004</a></FONT></TT></B>
<P>
The prize is being awarded jointly to: <p>
<a href="2004a.html">
<STRONG>A<font size=-1>ARON</font> C<font size=-1>IECHANOVER</font></strong></a>,
<a href="2004b.html">
<STRONG>A<font size=-1>VRAM</font> H<font size=-1>ERSHKO</FONT></strong>
</a>,
and
<a href="2004c.html"><STRONG>I<font size=-1>RWIN</font> R<font size=-1>OSE</font></strong></a>
for the discovery of ubiquitin-mediated protein degradation
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2003-->
<B><TT><FONT SIZE=+3><a href="/nobel/2003-prizes.html">2003</a></FONT></TT></B>
<P>
The prize is being awarded <p>
for discoveries concerning channels in cell membranes
<p>
with one half of the prize to: <p>
<a href="2003a.html">
<STRONG>P<font size=-1>ETER</font> A<font size=-1>GRE</font></strong></a>,
for the discovery of water channels
<p>
and the other half of the prize to: <p>
<a href="2003b.html">
<STRONG>R<font size=-1>ODERICK</font> M<font size=-1>AC</FONT>K<font size=-1>INNON</font></strong>
</a>
for structural and mechanistic studies of ion channels.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2002-->
<B><TT><FONT SIZE=+3><a href="/nobel/2002-prizes.html">2002</a></FONT></TT></B>
<P>
The prize is being awarded <p>
for the development of methods for identification and
structure analyses of biological macromolecules
<p>
with one half jointly to: <p>
<a href="2002a.html">
<STRONG>J<font size=-1>OHN</font> B<font size=-1>.</font> F<font size=-1>ENN</font></strong></a>, and
<a href="2002b.html">
<STRONG>K<font size=-1>OICHI</font> T<font size=-1>ANAKA</font></strong></a>,
for their development of soft desorption ionisation methods for mass
spectrometric analyses of biological macromolecules
<p>
and the other half to: <p>
<a href="2002c.html">
<STRONG>K<font size=-1>URT</font> W<font size=-1>ÜTHRICH</FONT></strong>
</a>
for his development of nuclear magnetic resonance spectroscopy for
determining the three-dimensional structure of biological
macromolecules in solution.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<!--2001-->
<B><TT><FONT SIZE=+3><a href="/nobel/2001-prizes.html">2001</a></FONT></TT></B>
<P>
The prize is being awarded with one half jointly to: <p>
<a href="2001a.html">
<STRONG>W<font size=-1>ILLIAM</font> S<font size=-1>.</font> K<font size=-1>NOWLES</font></strong></a>, and
<a href="2001b.html">
<STRONG>R<font size=-1>YOJI</font> N<font size=-1>OYORI</font></strong></a>,
for their work on chirally catalysed hydrogenation reactions
<p>
and the other half to: <p>
<a href="2001c.html">
<STRONG>K<font size=-1>.</font> B<font size=-1>ARRY</FONT> S<FONT SIZE-=1>HARPLESS</font></strong>
</a>
for his work on chirally catalysed oxidation reactions.
<!--2000-->
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3><a href="/nobel/2000-prizes.html">2000</a></FONT></TT></B>
<P>
The prize is being awarded with one half jointly to: <p>
<a href="2000a.html">
<STRONG>A<font size=-1>LAN</font> J<font size=-1>.</font> H<font size=-1>EEGER</font></strong></a>,
<a href="2000b.html">
<STRONG>A<font size=-1>LAN</font> G<font size=-1>.</font> M<font size=-1>AC</font>D<font size=-1>IARMID</font></strong></a>,
and
<a href="2000c.html">
<STRONG>H<font size=-1>IDEKI</font> S<font size=-1>HIRAKAWA</font></strong>
</a>
for the discovery and development of conductive polymers.
<!--1999-->
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3><a href="/nobel/1999-prizes.html">1999</a></FONT></TT></B>
<P>
<a href="1999a.html">
<STRONG> A<font size=-1>HMED</font> Z<font size=-1>EWAIL</font></strong></a>
for his studies of the transition states of chemical reactions using femtosecond spectroscopy.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3><a href="/nobel/1998-prizes.html">1998</a></FONT></TT></B>
<P>
The prize was awarded for
pioneering contributions in developing methods that can be used for theoretical studies of the properties of molecules and the chemical processes in which they are involved. The prize was divided equally between: <p>
<a href="1998a.html">
<STRONG> W<font size=-1>ALTER</font> K<font size=-1>OHN</font></strong></a>
for his development of the density-functional theory
<p>
and
<p>
<a href="1998b.html">
<STRONG> J<font size=-1>OHN</font> A. P<font size=-1>OPLE</font></strong></a>
for his development of computational methods in quantum chemistry.
<br>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3><a href="/nobel/1997-prizes.html">1997</a></FONT></TT></B>
<P>
The prize was divided, one half being awarded jointly to: <p>
<a href="1997a.html">
<STRONG> P<font size=-1>AUL</font> D. B<font size=-1>OYER</font></strong></a>
and
<a href="1997b.html">
<STRONG> J<font size=-1>OHN</font> E. W<font size=-1>ALKER</font></strong></a>
for their elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP)
<p>
and with one half to: <p>
<a href="1997c.html">
<STRONG> J<font size=-1>ENS</font> C. S<font size=-1>KOU</font></strong></a>
for the first discovery of an ion-transporting enzyme,
Na<SUP><FONT SIZE=2>+</FONT></SUP>, K<SUP><FONT SIZE=2>+</FONT></SUP>-ATPase.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3><a href="/nobel/1996-prizes.html">1996</a></FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1996a.html">
<STRONG>R<font size=-1>OBERT</font> F. C<font size=-1>URL,</font> J<font size=-1>r.</font></strong></a>
,
<a href="1996b.html">
<STRONG>S<font size=-1>IR</font> H<font size=-1>AROLD</font> W. K<font size=-1>ROTO</font></strong></a>
,
and
<a href="1996c.html">
<STRONG>R<font size=-1>ICHARD</font> E. S<font size=-1>MALLEY</font></strong></a>
for their discovery of fullerenes.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3><a href="/nobel/1995-prizes.html">1995</a></FONT></TT></B>
<P>
The <a href="http://www.nobel.se/announcement95-chemistry.html">prize</a> was awarded jointly to: <p>
<a href="1995a.html">
<STRONG>P<font size=-1>AUL</font> C<font size=-1>RUTZEN</font></strong></a>
,
<a href="1995b.html">
<STRONG>M<font size=-1>ARIO</font> M<font size=-1>OLINA</font></strong></a>
,
and
<a href="1995c.html">
<STRONG>F<font size=-1>.</font> S<font size=-1>HERWOOD</font> R<font size=-1>OWLAND</font></strong></a>
for their work in atmospheric chemistry, particularly concerning the formation and decomposition of ozone.
<br>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1994</FONT></TT></B>
<P>
<a href="1994a.html">
<STRONG> G<font size=-1>EORGE</font> A<font size=-1>.</font> O<font size=-1>LAH</font></strong></a>
for his contribution to carbocation chemistry.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1993</FONT></TT></B>
<P>
The prize was awarded for contributions to the developments of
methods within DNA-based chemistry equally between: <p>
<a href="1993a.html">
<STRONG> K<font size=-1>ARY</font> B<font size=-1>.</font> M<font size=-1>ULLIS</font></strong></a>
for his invention of the
polymerase chain reaction (PCR) method. <p>
and
<p>
<a href="1993b.html">
<STRONG> M<font size=-1>ICHAEL</font> S<font size=-1>MITH</font></strong></a>
for his fundamental
contributions to the establishment of oligonucleotide-based,
site-directed mutagenesis and its development for protein studies.
<br>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1992</FONT></TT></B>
<P>
<a href="1992a.html">
<STRONG> R<font size=-1>UDOLPH</font> A<font size=-1>.</font> M<font size=-1>ARCUS</font></strong></a>
for his contributions to the theory of electron transfer reactions in chemical systems. <p>
<br>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1991</FONT></TT></B>
<P>
<a href="1991a.html">
<STRONG> R<font size=-1>ICHARD</font> R<font size=-1>.</font> E<font size=-1>RNST</font></strong></a>
for his contributions to the development of the methodology of high resolution nuclear magnetic resonance (NMR) spectroscopy. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1990</FONT></TT></B>
<P>
<a href="1990a.html">
<STRONG> E<font size=-1>LIAS</font> J<font size=-1>AMES</font> C<font size=-1>OREY</font></strong></a>
for his development of the theory and methodology of organic synthesis. <p>
<br>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1989</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1989a.html">
<STRONG> S<font size=-1>IDNEY</font> A<font size=-1>LTMAN</font></strong></a>
and
<a href="1989b.html">
<STRONG> T<font size=-1>HOMAS</font> R<font size=-1>.</font> C<font size=-1>ECH</font></strong></a>
for their discovery of catalytic properties of RNA. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1988</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1988a.html">
<STRONG> J<font size=-1>OHANN</font> D<font size=-1>EISENHOFER</font></strong></a>
,
<a href="1988b.html">
<STRONG> R<font size=-1>OBERT</font> H<font size=-1>UBER</font></strong></a>
and
<a href="1988c.html">
<STRONG> H<font size=-1>ARTMUT</font> M<font size=-1>ICHEL</font></strong></a>
for the determination of the three-dimensional structure of a photosynthetic reaction centre. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1987</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1987a.html">
<STRONG> D<font size=-1>ONALD</font> J<font size=-1>.</font> C<font size=-1>RAM</font></strong></a>
,
<a href="1987b.html">
<STRONG> J<font size=-1>EAN</font>-M<font size=-1>ARIE</font> L<font size=-1>EHN</font></strong></a>
and
<a href="1987c.html">
<STRONG> C<font size=-1>HARLES</font> J<font size=-1>.</font> P<font size=-1>EDERSEN</font></strong></a>
<p>
for their development and use of molecules with structure-specific interactions of high selectivity. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1986</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1986a.html">
<STRONG> D<font size=-1>UDLEY</font> R<font size=-1>.</font> H<font size=-1>ERSCHBACH</font></strong></a>
,
<a href="1986b.html">
<STRONG> Y<font size=-1>UAN</font> T<font size=-1>.</font> L<font size=-1>EE</font></strong></a>
and
<a href="1986c.html">
<STRONG> J<font size=-1>OHN</font> C<font size=-1>.</font> P<font size=-1>OLANYI</font></strong></a>
for their contributions concerning the dynamics of chemical elementary processes. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1985</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1985a.html">
<STRONG> H<font size=-1>ERBERT</font> A<font size=-1>.</font> H<font size=-1>AUPTMAN</font></strong></a>
and
<a href="1985b.html">
<STRONG> J<font size=-1>EROME</font> K<font size=-1>ARLE</font></strong></a>
for their outstanding achievements in the development of direct methods for the determination of crystal structures. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1984</FONT></TT></B>
<P>
<a href="1984a.html">
<STRONG> R<font size=-1>OBERT</font> B<font size=-1>RUCE</font> M<font size=-1>ERRIFIELD</font></strong></a>
for his development of methodology for chemical synthesis on a solid matrix. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1983</FONT></TT></B>
<P>
<a href="1983a.html">
<STRONG> H<font size=-1>ENRY</font> T<font size=-1>AUBE</font></strong></a>
for his work on the mechanisms of electron transfer reactions, especially in metal complexes. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1982</FONT></TT></B>
<P>
<a href="1982a.html">
<STRONG> S<font size=-1>IR</font> A<font size=-1>ARON</font> K<font size=-1>LUG</font></strong></a>
for his development of crystallographic electron microscopy and his structural elucidation of biologically important nuclei acid-protein complexes. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1981</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1981a.html">
<STRONG> K<font size=-1>ENICHI</font> F<font size=-1>UKUI</font></strong></a>
and
<a href="1981b.html">
<STRONG> R<font size=-1>OALD</font> H<font size=-1>OFFMANN</font></strong></a>
for their theories, developed independently, concerning the course of chemical reactions. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1980</FONT></TT></B>
<P>
The prize was divided, one half being awarded to: <p>
<a href="1980a.html">
<STRONG> P<font size=-1>AUL</font> B<font size=-1>ERG</font></strong></a>
for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA
<p>
and the other half jointly to: <p>
<a href="1980b.html">
<STRONG> W<font size=-1>ALTER</font> G<font size=-1>ILBERT</font></strong></a>
and
<a href="1980c.html">
<STRONG> F<font size=-1>REDERICK</font> S<font size=-1>ANGER</font></strong></a>
for their contributions concerning the determination of base sequences in nucleic acids. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1979</FONT></TT></B>
<P>
The prize was divided equally between: <p>
<a href="1979a.html">
<STRONG> H<font size=-1>ERBERT</font> C<font size=-1>.</font> B<font size=-1>ROWN</font></strong></a>
and
<a href="1979b.html">
<STRONG> G<font size=-1>EORG</font> W<font size=-1>ITTIG</font></strong></a>
for their development of the use of boron- and phosphorus-containing compounds, respectively, into important reagents in organic synthesis. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1978</FONT></TT></B>
<P>
<a href="1978a.html">
<STRONG> P<font size=-1>ETER</font> D<font size=-1>.</font> M<font size=-1>ITCHELL</font></strong></a>
for his contribution to the understanding of biological energy transfer through the formulation of the chemiosmotic theory. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1977</FONT></TT></B>
<P>
<a href="1977a.html">
<STRONG> I<font size=-1>LYA</font> P<font size=-1>RIGOGINE</font></strong></a>
for his contributions to non-equilibrium thermodynamics, particularly the theory of dissipative structures. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1976</FONT></TT></B>
<P>
<a href="1976a.html">
<STRONG> W<font size=-1>ILLIAM</font> N<font size=-1>..</font> L<font size=-1>IPSCOMB</font></strong></a>
for his studies on the structure of boranes illuminating problems of chemical bonding. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1975</FONT></TT></B>
<P>
The prize was divided equally between: <p>
<a href="1975a.html">
<STRONG> S<font size=-1>IR</font> J<font size=-1>OHN</font> W<font size=-1>ARCUP</font> C<font size=-1>ORNFORTH</font></strong></a>
for his work on the stereochemistry of enzyme-catalyzed reactions
<br>
<p>
and<p>
<a href="1975b.html">
<STRONG> V<font size=-1>LADIMIR</font> P<font size=-1>RELOG</font></strong></a>
for his research into the stereochemistry of organic molecules and reactions. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1974</FONT></TT></B>
<P>
<a href="1974a.html">
<STRONG> P<font size=-1>AUL</font> J<font size=-1>.</font> F<font size=-1>LORY</font></strong></a>
for his fundamental achievements, both theoretical and experimental, in the physical chemistry of the macromolecules. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1973</FONT></TT></B>
<P>
The prize was divided equally between: <p>
<a href="1973a.html">
<STRONG> E<font size=-1>RNST</font> O<font size=-1>TTO</font> F<font size=-1>ISCHER</font></strong></a>
and
<a href="1973b.html">
<STRONG> S<font size=-1>IR</font> G<font size=-1>EOFFREY</font> W<font size=-1>ILKINSON</font></strong></a>
for their pioneering work, performed independently, on the chemistry of the organometallic, so called sandwich compounds. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1972</FONT></TT></B>
<P>
The prize was divided, one half being awarded to: <p>
<a href="1972a.html">
<STRONG> C<font size=-1>HRISTIAN</font> B<font size=-1>.</font> A<font size=-1>NFINSEN</font></strong></a>
for his work on ribonuclease, especially concerning the connection between the amino acid sequence and the biologically active confirmation
<p> and the other half jointly to: <p>
<a href="1972b.html">
<STRONG> S<font size=-1>TANFORD</font> M<font size=-1>OORE</font></strong></a>
and
<a href="1972c.html">
<STRONG> W<font size=-1>ILLIAM</font> H<font size=-1>.</font> S<font size=-1>TEIN</font></strong></a>
for their contribution to the understanding of the connection between chemical structure and catalytic activity of the active centre of the ribonuclease molecule. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1971</FONT></TT></B>
<P>
<a href="1971a.html">
<STRONG> G<font size=-1>ERHARD</font> H<font size=-1>ERZBERG</font></strong></a>
for his contributions to the knowledge of electronic stucture and geometry of molecules, particularly free radicals. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1970</FONT></TT></B>
<P>
<a href="1970a.html">
<STRONG> L<font size=-1>UIS</font> F<font size=-1>.</font> L<font size=-1>ELOIR</font></strong></a>
for his discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1969</FONT></TT></B>
<P>
The prize was divided equally between: <p>
<a href="1969a.html">
<STRONG> S<font size=-1>IR</font> D<font size=-1>EREK</font> H<font size=-1>.</font> R<font size=-1>.</font> B<font size=-1>ARTON</font></strong></a>
and
<a href="1969b.html">
<STRONG> O<font size=-1>DD</font> H<font size=-1>ASSEL</font></strong></a>
for their contributions to the development of the concept of conformation and its application in chemistry. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1968</FONT></TT></B>
<P>
<a href="1968a.html">
<STRONG> L<font size=-1>ARS</font> O<font size=-1>NSAGER</font></strong></a>
for the discovery of the reciprocal relations bearing his name, which are fundamental for the thermodynamics of irreversible processes. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1967</FONT></TT></B>
<P>
The prize was divided, one half being awarded to: <p>
<a href="1967a.html">
<STRONG> M<font size=-1>ANFRED</font> E<font size=-1>IGEN</font></strong></a>
<p> and the other half jointly to: <p>
<a href="1967b.html">
<STRONG> R<font size=-1>ONALD</font> G<font size=-1>EORGE</font> W<font size=-1>REYFORD</font> N<font size=-1>ORRISH</font></strong></a>
and
<a href="1967c.html">
<STRONG>L<font size=-1>ORD</font> G<font size=-1>EORGE</font> P<font size=-1>ORTER</font></strong></a>
for their studies of extremely fast chemical reactions, effected by disturbing the equlibrium by means of very short pulses of energy. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1966</FONT></TT></B>
<P>
<a href="1966a.html">
<STRONG> R<font size=-1>OBERT</font> S<font size=-1>.</font> M<font size=-1>ULLIKEN</font></strong></a>
for his fundamental work concerning chemical bonds and the electronic structure of molecules by the molecular orbital method. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1965</FONT></TT></B>
<P>
<a href="1965a.html">
<STRONG> R<font size=-1>OBERT</font> B<font size=-1>URNS</font> W<font size=-1>OODWARD</font></strong></a>
for his outstanding achievements in the art of organic synthesis. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1964</FONT></TT></B>
<P>
<a href="1964a.html">
<STRONG> D<font size=-1>OROTHY</font> C<font size=-1>ROWFOOT</font> H<font size=-1>ODGKIN</font></strong></a>
for her determinations by X-ray techniques of the structures of important biochemical substances. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1963</FONT></TT></B>
<P>
The prize was divided equally between: <p>
<a href="1963a.html">
<STRONG> K<font size=-1>ARL</font> Z<font size=-1>IEGLER</font></strong></a>
and
<a href="1963b.html">
<STRONG> G<font size=-1>IULIO</font> N<font size=-1>ATTA</font></strong></a>
for their discoveries in the field of the chemistry and technology of high polymers. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1962</FONT></TT></B>
<P>
The prize was divided equally between: <p>
<a href="1962a.html">
<STRONG> M<font size=-1>AX</font> F<font size=-1>ERDINAND</font> P<font size=-1>ERUTZ</font></strong></a>
and
<a href="1962b.html">
<STRONG> S<font size=-1>IR</font> J<font size=-1>OHN</font> C<font size=-1>OWDERY</font> K<font size=-1>ENDREW</font></strong></a>
for their studies of the structures of globular proteins. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1961</FONT></TT></B>
<P>
<a href="1961a.html">
<STRONG> M<font size=-1>ELVIN</font> C<font size=-1>ALVIN</font></strong></a>
for his research on the carbon dioxide assimilation in plants. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1960</FONT></TT></B>
<P>
<a href="1960a.html">
<STRONG> W<font size=-1>ILLARD</font> F<font size=-1>RANK</font> L<font size=-1>IBBY</font></strong></a>
for his method to use carbon-14 for age determination in archaeology, geology, geophysics, and other branches of science. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1959</FONT></TT></B>
<P>
<a href="1959a.html">
<STRONG> J<font size=-1>AROSLAV</font> H<font size=-1>EYROVSKY</font></strong></a>
for his discovery and development of the polarographic methods of analysis. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1958</FONT></TT></B>
<P>
<a href="1958a.html">
<STRONG> F<font size=-1>REDERICK</font> S<font size=-1>ANGER</font></strong></a>
for his work on the structure of proteins, especially that of insulin. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1957</FONT></TT></B>
<P>
<a href="1957a.html">
<STRONG>L<font size=-1>ORD</font> A<font size=-1>LEXANDER</font> R<font size=-1>.</font> T<font size=-1>ODD</font></strong></a>
for his work on nucleotides and nucleotide co-enzymes. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1956</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1956a.html">
<STRONG> S<font size=-1>IR</font> C<font size=-1>YRIL</font> N<font size=-1>ORMAN</font> H<font size=-1>INSHELWOOD</font></strong></a>
and
<a href="1956b.html">
<STRONG>N<font size=-1>IKOLAY</font> N<font size=-1>IKOLAEVICH</font> S<font size=-1>EMENOV</font> </strong></a>
for their researches into the mechanism of chemical reactions. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1955</FONT></TT></B>
<P>
<a href="1955a.html">
<STRONG> V<font size=-1>INCENT</font> D<font size=-1>U</font> V<font size=-1>IGNEAUD</font></strong></a>
for his work on biochemically important sulphur compounds, especially for the first synthesis of a polypeptide hormone. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1954</FONT></TT></B>
<P>
<a href="1954a.html">
<STRONG> L<font size=-1>INUS</font> C<font size=-1>ARL</font> P<font size=-1>AULING</font></strong></a>
for his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1953</FONT></TT></B>
<P>
<a href="1953a.html">
<STRONG> H<font size=-1>ERMANN</font> S<font size=-1>TAUDINGER</font></strong></a>
for his discoveries in the field of macromolecular chemistry. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1952</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1952a.html">
<STRONG> A<font size=-1>RCHER</font> J<font size=-1>OHN</font> P<font size=-1>ORTER</font> M<font size=-1>ARTIN</font></strong></a>
and
<a href="1952b.html">
<STRONG> R<font size=-1>ICHARD</font> L<font size=-1>AURENCE</font> M<font size=-1>ILLINGTON</font> S<font size=-1>YNGE</font></strong></a>
for their invention of partition chromatography. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1951</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1951a.html">
<STRONG> E<font size=-1>DWIN</font> M<font size=-1>ATTISON</font> M<font size=-1>C</font> M<font size=-1>ILLAN</font></strong></a>
and
<a href="1951b.html">
<STRONG> G<font size=-1>LENN</font> T<font size=-1>HEODORE</font> S<font size=-1>EABORG</font></strong></a>
for their discoveries in the chemistry of the transuranium elements. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1950</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1950a.html">
<STRONG> O<font size=-1>TTO</font> P<font size=-1>AUL</font> H<font size=-1>ERMANN</font> D<font size=-1>IELS</font></strong></a>
and
<a href="1950b.html">
<STRONG> K<font size=-1>URT</font> A<font size=-1>LDER</font></strong></a>
for their discovery and development of the diene synthesis. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1949</FONT></TT></B>
<P>
<a href="1949a.html">
<STRONG> W<font size=-1>ILLIAM</font> F<font size=-1>RANCIS</font> G<font size=-1>IAUQUE</font></strong></a>
for his contributions in the field of chemical thermodynamics, particularly concerning the behaviour of substances at extremely low temperatures. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1948</FONT></TT></B>
<P>
<a href="1948a.html">
<STRONG> A<font size=-1>RNE</font> W<font size=-1>ILHELM</font> K<font size=-1>AURIN</font> T<font size=-1>ISELIUS</font></strong></a>
for his research on electrophoresis and adsorption analysis, especially for his discoveries concerning the complex nature of the serum proteins. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1947</FONT></TT></B>
<P>
<a href="1947a.html">
<STRONG> S<font size=-1>IR</font> R<font size=-1>OBERT</font> R<font size=-1>OBINSON</font></strong></a>
for his investigations on plant products of biological importance, especially the alkaloids. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1946</FONT></TT></B>
<P>
The prize was divided, one half being awarded to: <p>
<a href="1946a.html">
<STRONG> J<font size=-1>AMES</font> B<font size=-1>ATCHELLER</font> S<font size=-1>UMNER</font></strong></a>
for his discovery that enzymes can be crystallized.
<p> the other half jointly to <p>
<a href="1946b.html">
<STRONG> J<font size=-1>OHN</font> H<font size=-1>OWARD</font> N<font size=-1>ORTHROP</font></strong></a>
and
<a href="1946c.html">
<STRONG> W<font size=-1>ENDELL</font> M<font size=-1>EREDITH</font> S<font size=-1>TANLEY</font></strong></a>
for their preparation of enzymes and virus proteins in a pure form. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1945</FONT></TT></B>
<P>
<a href="1945a.html">
<STRONG> A<font size=-1>RTTURI</font> I<font size=-1>LMARI</font> V<font size=-1>IRTANEN</font></strong></a>
for his research and inventions in agricultural and nutrition chemistry, especially for his fodder preservation method. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1944</FONT></TT></B>
<P>
<a href="1944a.html">
<STRONG> O<font size=-1>TTO</font> H<font size=-1>AHN</font></strong></a>
for his discovery of the fission of
heavy nuclei. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1943</FONT></TT></B>
<P>
<a href="1943a.html">
<STRONG> G<font size=-1>EORGE</font> D<font size=-1>E</font> H<font size=-1>EVESY</font></strong></a>
for his work on the use of isotopes as tracers in the study of chemical processes. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<H2>1942-1940</H2>
The prize money was allocated to the Main Fund (1/3) and to the
Special Fund (2/3) of this prize section.
<br>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1939</FONT></TT></B>
<P>
<a href="1939a.html">
<STRONG> A<font size=-1>DOLF</font> F<font size=-1>RIEDRICH</font> J<font size=-1>OHANN</font> B<font size=-1>UTENANDT</font></strong></a>
for his work on sex hormones. (Caused by the authorities of
his country to decline the award but later received the
diploma and the medal).
<p>
and
<p>
<a href="1939b.html">
<STRONG>L<font size=-1>EOPOLD</font> R<font size=-1>UZICKA</font> </strong></a>
for his work on polymethylenes and higher terpenes. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1938</FONT></TT></B>
<P>
<a href="1938a.html">
<STRONG> R<font size=-1>ICHARD</font> K<font size=-1>UHN</font></strong></a>
for his work
on carotenoids and vitamins. (Caused by the authorities of his
country to decline the award but later received the diploma
and the medal.)
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1937</FONT></TT></B>
<P>
The prize was divided equally between: <p>
<a href="1937a.html">
<STRONG> S<font size=-1>IR</font> W<font size=-1>ALTER</font> N<font size=-1>ORMAN</font> H<font size=-1>AWORTH</font></strong></a>
for his investigations on carbohydrates and vitamin C. <p>
and<p>
<a href="1937b.html">
<STRONG> P<font size=-1>AUL</font> K<font size=-1>ARRER</font></strong></a>
for his investigations on carotenoids, flavins and vitamins A and B2. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1936</FONT></TT></B>
<P>
<a href="1936a.html">
<STRONG> P<font size=-1>ETRUS</font> (P<font size=-1>ETER</font>) J<font size=-1>OSEPHUS</font> W<font size=-1>ILHELMUS</font> D<font size=-1>EBYE</font></strong></a>
for his contributions to our knowledge of molecular structure through his investigations on dipole moments and on the diffraction of X-rays and electrons in gases. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1935</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1935a.html">
<STRONG> F<font size=-1>RÉDÉRIC</font> J<font size=-1>OLIOT</font></strong></a>
and
<a href="1935b.html">
<STRONG> I<font size=-1>RÈNE</font> J<font size=-1>OLIOT-CURIE</font></strong></a>
in recognition of their synthesis of new radioactive elements. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1934</FONT></TT></B>
<P>
<a href="1934a.html">
<STRONG> H<font size=-1>AROLD</font> C<font size=-1>LAYTON</font> U<font size=-1>REY</font></strong></a>
for his discovery of heavy hydrogen. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1933</FONT></TT></B>
<P>
The prize money was allocated to the Main Fund (1/3) and to the
Special Fund (2/3) of this prize section.
<br>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1932</FONT></TT></B>
<P>
<a href="1932a.html">
<STRONG> I<font size=-1>RVING</font> L<font size=-1>ANGMUIR</font></strong></a>
for his discoveries and investigations in surface chemistry. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1931</FONT></TT></B>
<P>
The prize was awarded jointly to: <p>
<a href="1931a.html">
<STRONG> C<font size=-1>ARL</font> B<font size=-1>OSCH</font></strong></a>
and
<a href="1931b.html">
<STRONG> F<font size=-1>RIEDRICH</font> B<font size=-1>ERGIUS</font></strong></a>
in recognition of their contributions to the invention and development of chemical high pressure methods. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1930</FONT></TT></B>
<P>
<a href="1930a.html">
<STRONG> H<font size=-1>ANS</font> F<font size=-1>ISCHER</font></strong></a>
for his researches into the constitution of haemin and chlorophyll and especially for his synthesis of haemin. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1929</FONT></TT></B>
<P>
The prize was divided equally between: <p>
<a href="1929a.html">
<STRONG> S<font size=-1>IR</font> A<font size=-1>RTHUR</font> H<font size=-1>ARDEN</font></strong></a>
and
<a href="1929b.html">
<STRONG> H<font size=-1>ANS</font> K<font size=-1>ARL</font> A<font size=-1>UGUST</font> S<font size=-1>IMON</font> V<font size=-1>ON</font> E<font size=-1>ULER</font>-C<font size=-1>HELPIN</font></strong></a>
for their investigations on the fermentation of sugar and fermentative enzymes. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1928</FONT></TT></B>
<P>
<a href="1928a.html">
<STRONG> A<font size=-1>DOLF</font> O<font size=-1>TTO</font> R<font size=-1>EINHOLD</font> W<font size=-1>INDAUS</font></strong></a>
for the services rendered through his research into the constitution of the sterols and their connection with the vitamins. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1927</FONT></TT></B>
<P>
<a href="1927a.html">
<STRONG> H<font size=-1>EINRICH</font> O<font size=-1>TTO</font> W<font size=-1>IELAND</font></strong></a>
for his investigations of the
constitution of the bile acids and related substances.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1926</FONT></TT></B>
<P>
<a href="1926a.html">
<STRONG> T<font size=-1>HE</font> (T<font size=-1>HEODOR</font>) S<font size=-1>VEDBERG</font></strong></a>
for his work on disperse systems. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1925</FONT></TT></B>
<P>
<a href="1925a.html">
<STRONG> R<font size=-1>ICHARD</font> A<font size=-1>DOLF</font> Z<font size=-1>SIGMONDY</font></strong></a>
for his demonstration of the heterogenous
nature of colloid solutions and for the methods he used, which have
since become fundamental in modern colloid chemistry. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1924</FONT></TT></B>
<P>
The prize money for 1924 was allocated to the Special Fund
of this prize section. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1923</FONT></TT></B>
<P>
<a href="1923a.html">
<STRONG> F<font size=-1>RITZ</font> P<font size=-1>REGL</font></strong></a>
for his invention of the method of micro-analysis of organic substances. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1922</FONT></TT></B>
<P>
<a href="1922a.html">
<STRONG> F<font size=-1>RANCIS</font> W<font size=-1>ILLIAM</font> A<font size=-1>STON</font></strong></a>
for his discovery, by means of his mass spectrograph, of isotopes, in a large number of non-radioactive elements, and for his enunciation of the whole-number rule. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1921</FONT></TT></B>
<P>
<a href="1921a.html">
<STRONG> F<font size=-1>REDERICK</font> S<font size=-1>ODDY</font></strong></a>
, for his contributions to our knowledge of the chemistry of radioactive substances, and his investigations into the origin and nature of isotopes. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1920</FONT></TT></B>
<P>
<a href="1920a.html">
<STRONG> W<font size=-1>ALTHER</font> H<font size=-1>ERMANN</font> N<font size=-1>ERNST</font></strong></a>
in recognition of his work in thermochemistry. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1919</FONT></TT></B>
<P>
The prize money for 1919 was allocated to the Special Fund of this prize section. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1918</FONT></TT></B>
<P>
<a href="1918a.html">
<STRONG> F<font size=-1>RITZ</font> H<font size=-1>ABER</font></strong></a>
for the synthesis of ammonia from its elements.
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<H2>1917-1916</H2>
The prize money for 1917-1916 was allocated to the Special
Fund of this prize section.
<br>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1915</FONT></TT></B>
<P>
<a href="1915a.html">
<STRONG> R<font size=-1>ICHARD</font> M<font size=-1>ARTIN</font> W<font size=-1>ILLSTÄTTER</font></strong></a>
for his researches on plant pigments, especially chlorophyll. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1914</FONT></TT></B>
<P>
<a href="1914a.html">
<STRONG> T<font size=-1>HEODORE</font> W<font size=-1>ILLIAM</font> R<font size=-1>ICHARDS</font></strong></a>
, in recognition of his accurate determinations of the atomic weight of a large number of chemical elements. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1913</FONT></TT></B>
<P>
<a href="1913a.html">
<STRONG> A<font size=-1>LFRED</font> W<font size=-1>ERNER</font></strong></a>
in recognition of his work on the linkage of atoms in molecules by which he has thrown new light on earlier investigations and opened up new fields of research especially in inorganic chemistry. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1912</FONT></TT></B>
<P>
The prize was divided equally between: <p>
<a href="1912a.html">
<STRONG> V<font size=-1>ICTOR</font> G<font size=-1>RIGNARD</font></strong></a>
for the discovery of the so-called Grignard reagent, which in recent years has greatly advanced the progress of organic chemistry
<p>
and
<p>
<a href="1912b.html">
<STRONG> P<font size=-1>AUL</font> S<font size=-1>ABATIER</font></strong></a>
for his method of hydrogenating organic compounds in the presence of finely disintegrated metals whereby the progress of organic chemistry has been greatly advanced in recent years. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1911</FONT></TT></B>
<P>
<a href="1911a.html">
<STRONG> M<font size=-1>ARIE</font> C<font size=-1>URIE</font></strong></a>,
née Marie Sklodowska,
<a href="1911b.html">
<STRONG> </strong></a>
in recognition of her services to the advancement of chemistry by the discovery of the elements radium and polonium, by the isolation of radium and the study of the nature and compounds of this remarkable element. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1910</FONT></TT></B>
<P>
<a href="1910a.html">
<STRONG> O<font size=-1>TTO</font> W<font size=-1>ALLACH</font></strong></a>
in recognition of his services to organic chemistry and the chemical industry by his pioneer work in the field of alicyclic compounds. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1909</FONT></TT></B>
<P>
<a href="1909a.html">
<STRONG> W<font size=-1>ILHELM</font> O<font size=-1>STWALD</font></strong></a>
in recognition of his work on catalysis and for his investigations into the fundamental principles governing chemical equilibria and rates of reaction. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1908</FONT></TT></B>
<P>
<a href="1908a.html">
<STRONG>L<font size=-1>ORD</font> E<font size=-1>RNEST</font> R<font size=-1>UTHERFORD</font></strong></a>
for his investigations into the disintegration of the elements, and the chemistry of radioactive substances. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1907</FONT></TT></B>
<P>
<a href="1907a.html">
<STRONG> E<font size=-1>DUARD</font> B<font size=-1>UCHNER</font></strong></a>
for his biochemical researches and his discovery of cellfree fermentation. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1906</FONT></TT></B>
<P>
<a href="1906a.html">
<STRONG> H<font size=-1>ENRI</font> M<font size=-1>OISSAN</font></strong></a>
in recognition of the great services rendered by him in his investigation and isolation of the element fluorine, and for the adoption in the service of science of the electric furnace called after him. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1905</FONT></TT></B>
<P>
<a href="1905a.html">
<STRONG> J<font size=-1>OHANN</font> F<font size=-1>RIEDRICH</font> W<font size=-1>ILHELM</font> A<font size=-1>DOLF</font> V<font size=-1>ON</font> B<font size=-1>AEYER</font></strong></a>
in recognition of his services in the advancement of organic chemistry and the chemical industry, through his work on organic dyes and hydroaromatic compounds. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1904</FONT></TT></B>
<P>
<a href="1904a.html">
<STRONG> S<font size=-1>IR</font> W<font size=-1>ILLIAM</font> R<font size=-1>AMSAY</font></strong></a>
in recognition of his services in the discovery of the inert gaseous elements in air, and his determination of their place in the periodic system. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1903</FONT></TT></B>
<P>
<a href="1903a.html">
<STRONG> S<font size=-1>VANTE</font> A<font size=-1>UGUST</font> A<font size=-1>RRHENIUS</font></strong></a>
in recognition of the extraordinary services he has rendered to the advancement of chemistry by his electrolytic theory of dissociation. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1902</FONT></TT></B>
<P>
<a href="1902a.html">
<STRONG> H<font size=-1>ERMANN</font> E<font size=-1>MIL</font> F<font size=-1>ISCHER</font></strong></a>
in recognition of the extraordinary services he has rendered by his work on sugar and purine syntheses. <p>
<p>
<center>
<img src="images/ruler.gif" alt="" border=0>
</center>
<B><TT><FONT SIZE=+3>1901</FONT></TT></B>
<P>
<a href="1901a.html">
<STRONG> J<font size=-1>ACOBUS</font> H<font size=-1>ENRICUS</font> V<font size=-1>AN'T</font> H<font size=-1>OFF</font></strong></a>
in recognition of the extraordinary services he has rendered by the discovery of the laws of chemical dynamics and osmotic pressure in solutions. <p>
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Winners of the Nobel Prize in Chemistry
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| Nobel Prize in Chemistry Winners 2022-1901
([also available in alphabetical arrangement](alpha.html))
| Nobel Prize in Chemistry |
##### brought to you by
**[The Nobel Prize Internet Archive](../nobel.html)**
![](images/ruler.gif)
| | |
| --- | --- |
|
**[2022](/nobel/2022-prizes.html)**
The prize was awarded to:
**CAROLYN R. BERTOZZI**,
**MORTEN MELDAL**,
and
**K. BARRY SHARPLESS**
for the development of click chemistry and bioorthogonal chemistry
**[2021](/nobel/2021-prizes.html)**
The prize was awarded jointly to:
**BENJAMIN LIST**,
and
**DAVID W. C. MACMILLAN**
for the development of asymmetric organocatalysis.
**[2020](/nobel/2020-prizes.html)**
The prize was awarded to:
**EMMANUELLE CHARPENTIER**,
and
**JENNIFER A. DOUDNA**
for the development of a method for genome editing.
**[2019](/nobel/2019-prizes.html)**
The prize was awarded to:
**JOHN GOODENOUGH**,
**M. STANLEY WHITTINGHAM** ,
and
**AKIRA YOSHINO**
for the development of lithium-ion batteries
**[2018](/nobel/2018-prizes.html)**
The prize was awarded with one half to:
**FRANCES H. ARNOLD**,
for the directed evolution of enzymes
and the other half jointly to:
**GEORGE P. SMITH** ,
and
**SIR GREGORY P. WINTER**
for the phage display of peptides and antibodies
**[2017](/nobel/2017-prizes.html)**
The prize was awarded jointly to:
**JACQUES DUBOCHET**,
**JOACHIM FRANK** ,
and
**RICHRD HENDERSON**
for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution.
**[2016](/nobel/2016-prizes.html)**
The prize was awarded jointly to:
[**JEAN-PIERRE SAUVAGE**](2016a.html),
[**SIR J. FRASER STODDART**](2016b.html),
and
[**BERNARD L. FERINGA**](2016c.html)
for the design and synthesis of molecular machines.
**[2015](/nobel/2015-prizes.html)**
The prize was awarded jointly to:
**TOMAS LINDAHL**,
**PAUL MODRICH**,
and
**AZIZ SANCAR**
for mechanistic studies of DNA repair.
**[2014](/nobel/2014-prizes.html)**
The prize was awarded jointly to:
**ERIC BETZIG**,
**STEFAN W. HELL**,
and
**WILLIAM E. MOERNER**
for the development of super-resolved fluorescence microscopy.
**[2013](/nobel/2013-prizes.html)**
The prize was awarded jointly to:
[**MARTIN KARPLUS**](2013a.html),
[**MICHAEL LEVITT**](2013b.html),
and
[**ARIEH WARSHEL**](2013c.html)
for the development of multiscale models for complex chemical systems.
**[2012](/nobel/2012-prizes.html)**
The prize was awarded jointly to:
[**ROBERT J. LEFKOWITZ**](2012a.html)
and
[**BRIAN K. KOBILKA**](2012b.html)
for studies of G-protein-coupled receptors.
**[2011](/nobel/2011-prizes.html)**
The prize was awarded to:
[**DANIEL SHECHTMAN**](2011a.html)
for the discovery of quasicrystals.
**[2010](/nobel/2010-prizes.html)**
The prize was awarded jointly to:
[**RICHARD F. HECK**](2010a.html),
[**EI-ICHI NEGISHI**](2010b.html),
and
[**AKIRA SUZUKI**](2010c.html)
for palladium-catalyzed cross couplings in organic synthesis.
**[2009](/nobel/2009-prizes.html)**
The prize goes to:
[**VENKATRAMAN RAMAKRISHNAN**](2009a.html),
[**THOMAS A. STEITZ**](2009b.html),
and
[**ADA E. YONATH**](2009c.html) for studies of the structure and function of the ribosome.
**[2008](/nobel/2008-prizes.html)**
The prize goes to:
[**OSAMU SHIMOMURA**](2008a.html),
[**MARTIN CHALFIE**](2008b.html),
and
[**ROGER Y TSIEN**](2008c.html) for the discovery and development of the green fluorescent protein, GFP.
**[2007](/nobel/2007-prizes.html)**
The prize goes to:
[**GERHARD ERTL**](2007a.html) for his studies of chemical processes on solid surfaces.
**[2006](/nobel/2006-prizes.html)**
The prize goes to:
[**ROGER D. KORNBERG**](2006a.html) for his studies of the molecular basis of eukaryotic transcription.
**[2005](/nobel/2005-prizes.html)**
The prize is being awarded jointly to:
[**YVES CHAUVIN**](2005a.html),
[**ROBERT H. GRUBBS**](2005b.html),
and
[**RICHARD R. SCHROCK**](2005c.html)
for the development of the metathesis method in organic synthesis.
**[2004](/nobel/2004-prizes.html)**
The prize is being awarded jointly to:
[**AARON CIECHANOVER**](2004a.html),
[**AVRAM HERSHKO**](2004b.html),
and
[**IRWIN ROSE**](2004c.html)
for the discovery of ubiquitin-mediated protein degradation
**[2003](/nobel/2003-prizes.html)**
The prize is being awarded
for discoveries concerning channels in cell membranes
with one half of the prize to:
[**PETER AGRE**](2003a.html),
for the discovery of water channels
and the other half of the prize to:
[**RODERICK MACKINNON**](2003b.html)
for structural and mechanistic studies of ion channels.
**[2002](/nobel/2002-prizes.html)**
The prize is being awarded
for the development of methods for identification and
structure analyses of biological macromolecules
with one half jointly to:
[**JOHN B. FENN**](2002a.html), and
[**KOICHI TANAKA**](2002b.html),
for their development of soft desorption ionisation methods for mass
spectrometric analyses of biological macromolecules
and the other half to:
[**KURT WÜTHRICH**](2002c.html)
for his development of nuclear magnetic resonance spectroscopy for
determining the three-dimensional structure of biological
macromolecules in solution.
**[2001](/nobel/2001-prizes.html)**
The prize is being awarded with one half jointly to:
[**WILLIAM S. KNOWLES**](2001a.html), and
[**RYOJI NOYORI**](2001b.html),
for their work on chirally catalysed hydrogenation reactions
and the other half to:
[**K. BARRY SHARPLESS**](2001c.html)
for his work on chirally catalysed oxidation reactions.
**[2000](/nobel/2000-prizes.html)**
The prize is being awarded with one half jointly to:
[**ALAN J. HEEGER**](2000a.html),
[**ALAN G. MACDIARMID**](2000b.html),
and
[**HIDEKI SHIRAKAWA**](2000c.html)
for the discovery and development of conductive polymers.
**[1999](/nobel/1999-prizes.html)**
[**AHMED ZEWAIL**](1999a.html)
for his studies of the transition states of chemical reactions using femtosecond spectroscopy.
**[1998](/nobel/1998-prizes.html)**
The prize was awarded for
pioneering contributions in developing methods that can be used for theoretical studies of the properties of molecules and the chemical processes in which they are involved. The prize was divided equally between:
[**WALTER KOHN**](1998a.html)
for his development of the density-functional theory
and
[**JOHN A. POPLE**](1998b.html)
for his development of computational methods in quantum chemistry.
**[1997](/nobel/1997-prizes.html)**
The prize was divided, one half being awarded jointly to:
[**PAUL D. BOYER**](1997a.html)
and
[**JOHN E. WALKER**](1997b.html)
for their elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP)
and with one half to:
[**JENS C. SKOU**](1997c.html)
for the first discovery of an ion-transporting enzyme,
Na+, K+-ATPase.
**[1996](/nobel/1996-prizes.html)**
The prize was awarded jointly to:
[**ROBERT F. CURL, Jr.**](1996a.html)
,
[**SIR HAROLD W. KROTO**](1996b.html)
,
and
[**RICHARD E. SMALLEY**](1996c.html)
for their discovery of fullerenes.
**[1995](/nobel/1995-prizes.html)**
The [prize](http://www.nobel.se/announcement95-chemistry.html) was awarded jointly to:
[**PAUL CRUTZEN**](1995a.html)
,
[**MARIO MOLINA**](1995b.html)
,
and
[**F. SHERWOOD ROWLAND**](1995c.html)
for their work in atmospheric chemistry, particularly concerning the formation and decomposition of ozone.
**1994**
[**GEORGE A. OLAH**](1994a.html)
for his contribution to carbocation chemistry.
**1993**
The prize was awarded for contributions to the developments of
methods within DNA-based chemistry equally between:
[**KARY B. MULLIS**](1993a.html)
for his invention of the
polymerase chain reaction (PCR) method.
and
[**MICHAEL SMITH**](1993b.html)
for his fundamental
contributions to the establishment of oligonucleotide-based,
site-directed mutagenesis and its development for protein studies.
**1992**
[**RUDOLPH A. MARCUS**](1992a.html)
for his contributions to the theory of electron transfer reactions in chemical systems.
**1991**
[**RICHARD R. ERNST**](1991a.html)
for his contributions to the development of the methodology of high resolution nuclear magnetic resonance (NMR) spectroscopy.
**1990**
[**ELIAS JAMES COREY**](1990a.html)
for his development of the theory and methodology of organic synthesis.
**1989**
The prize was awarded jointly to:
[**SIDNEY ALTMAN**](1989a.html)
and
[**THOMAS R. CECH**](1989b.html)
for their discovery of catalytic properties of RNA.
**1988**
The prize was awarded jointly to:
[**JOHANN DEISENHOFER**](1988a.html)
,
[**ROBERT HUBER**](1988b.html)
and
[**HARTMUT MICHEL**](1988c.html)
for the determination of the three-dimensional structure of a photosynthetic reaction centre.
**1987**
The prize was awarded jointly to:
[**DONALD J. CRAM**](1987a.html)
,
[**JEAN-MARIE LEHN**](1987b.html)
and
[**CHARLES J. PEDERSEN**](1987c.html)
for their development and use of molecules with structure-specific interactions of high selectivity.
**1986**
The prize was awarded jointly to:
[**DUDLEY R. HERSCHBACH**](1986a.html)
,
[**YUAN T. LEE**](1986b.html)
and
[**JOHN C. POLANYI**](1986c.html)
for their contributions concerning the dynamics of chemical elementary processes.
**1985**
The prize was awarded jointly to:
[**HERBERT A. HAUPTMAN**](1985a.html)
and
[**JEROME KARLE**](1985b.html)
for their outstanding achievements in the development of direct methods for the determination of crystal structures.
**1984**
[**ROBERT BRUCE MERRIFIELD**](1984a.html)
for his development of methodology for chemical synthesis on a solid matrix.
**1983**
[**HENRY TAUBE**](1983a.html)
for his work on the mechanisms of electron transfer reactions, especially in metal complexes.
**1982**
[**SIR AARON KLUG**](1982a.html)
for his development of crystallographic electron microscopy and his structural elucidation of biologically important nuclei acid-protein complexes.
**1981**
The prize was awarded jointly to:
[**KENICHI FUKUI**](1981a.html)
and
[**ROALD HOFFMANN**](1981b.html)
for their theories, developed independently, concerning the course of chemical reactions.
**1980**
The prize was divided, one half being awarded to:
[**PAUL BERG**](1980a.html)
for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA
and the other half jointly to:
[**WALTER GILBERT**](1980b.html)
and
[**FREDERICK SANGER**](1980c.html)
for their contributions concerning the determination of base sequences in nucleic acids.
**1979**
The prize was divided equally between:
[**HERBERT C. BROWN**](1979a.html)
and
[**GEORG WITTIG**](1979b.html)
for their development of the use of boron- and phosphorus-containing compounds, respectively, into important reagents in organic synthesis.
**1978**
[**PETER D. MITCHELL**](1978a.html)
for his contribution to the understanding of biological energy transfer through the formulation of the chemiosmotic theory.
**1977**
[**ILYA PRIGOGINE**](1977a.html)
for his contributions to non-equilibrium thermodynamics, particularly the theory of dissipative structures.
**1976**
[**WILLIAM N.. LIPSCOMB**](1976a.html)
for his studies on the structure of boranes illuminating problems of chemical bonding.
**1975**
The prize was divided equally between:
[**SIR JOHN WARCUP CORNFORTH**](1975a.html)
for his work on the stereochemistry of enzyme-catalyzed reactions
and
[**VLADIMIR PRELOG**](1975b.html)
for his research into the stereochemistry of organic molecules and reactions.
**1974**
[**PAUL J. FLORY**](1974a.html)
for his fundamental achievements, both theoretical and experimental, in the physical chemistry of the macromolecules.
**1973**
The prize was divided equally between:
[**ERNST OTTO FISCHER**](1973a.html)
and
[**SIR GEOFFREY WILKINSON**](1973b.html)
for their pioneering work, performed independently, on the chemistry of the organometallic, so called sandwich compounds.
**1972**
The prize was divided, one half being awarded to:
[**CHRISTIAN B. ANFINSEN**](1972a.html)
for his work on ribonuclease, especially concerning the connection between the amino acid sequence and the biologically active confirmation
and the other half jointly to:
[**STANFORD MOORE**](1972b.html)
and
[**WILLIAM H. STEIN**](1972c.html)
for their contribution to the understanding of the connection between chemical structure and catalytic activity of the active centre of the ribonuclease molecule.
**1971**
[**GERHARD HERZBERG**](1971a.html)
for his contributions to the knowledge of electronic stucture and geometry of molecules, particularly free radicals.
**1970**
[**LUIS F. LELOIR**](1970a.html)
for his discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates.
**1969**
The prize was divided equally between:
[**SIR DEREK H. R. BARTON**](1969a.html)
and
[**ODD HASSEL**](1969b.html)
for their contributions to the development of the concept of conformation and its application in chemistry.
**1968**
[**LARS ONSAGER**](1968a.html)
for the discovery of the reciprocal relations bearing his name, which are fundamental for the thermodynamics of irreversible processes.
**1967**
The prize was divided, one half being awarded to:
[**MANFRED EIGEN**](1967a.html)
and the other half jointly to:
[**RONALD GEORGE WREYFORD NORRISH**](1967b.html)
and
[**LORD GEORGE PORTER**](1967c.html)
for their studies of extremely fast chemical reactions, effected by disturbing the equlibrium by means of very short pulses of energy.
**1966**
[**ROBERT S. MULLIKEN**](1966a.html)
for his fundamental work concerning chemical bonds and the electronic structure of molecules by the molecular orbital method.
**1965**
[**ROBERT BURNS WOODWARD**](1965a.html)
for his outstanding achievements in the art of organic synthesis.
**1964**
[**DOROTHY CROWFOOT HODGKIN**](1964a.html)
for her determinations by X-ray techniques of the structures of important biochemical substances.
**1963**
The prize was divided equally between:
[**KARL ZIEGLER**](1963a.html)
and
[**GIULIO NATTA**](1963b.html)
for their discoveries in the field of the chemistry and technology of high polymers.
**1962**
The prize was divided equally between:
[**MAX FERDINAND PERUTZ**](1962a.html)
and
[**SIR JOHN COWDERY KENDREW**](1962b.html)
for their studies of the structures of globular proteins.
**1961**
[**MELVIN CALVIN**](1961a.html)
for his research on the carbon dioxide assimilation in plants.
**1960**
[**WILLARD FRANK LIBBY**](1960a.html)
for his method to use carbon-14 for age determination in archaeology, geology, geophysics, and other branches of science.
**1959**
[**JAROSLAV HEYROVSKY**](1959a.html)
for his discovery and development of the polarographic methods of analysis.
**1958**
[**FREDERICK SANGER**](1958a.html)
for his work on the structure of proteins, especially that of insulin.
**1957**
[**LORD ALEXANDER R. TODD**](1957a.html)
for his work on nucleotides and nucleotide co-enzymes.
**1956**
The prize was awarded jointly to:
[**SIR CYRIL NORMAN HINSHELWOOD**](1956a.html)
and
[**NIKOLAY NIKOLAEVICH SEMENOV**](1956b.html)
for their researches into the mechanism of chemical reactions.
**1955**
[**VINCENT DU VIGNEAUD**](1955a.html)
for his work on biochemically important sulphur compounds, especially for the first synthesis of a polypeptide hormone.
**1954**
[**LINUS CARL PAULING**](1954a.html)
for his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances.
**1953**
[**HERMANN STAUDINGER**](1953a.html)
for his discoveries in the field of macromolecular chemistry.
**1952**
The prize was awarded jointly to:
[**ARCHER JOHN PORTER MARTIN**](1952a.html)
and
[**RICHARD LAURENCE MILLINGTON SYNGE**](1952b.html)
for their invention of partition chromatography.
**1951**
The prize was awarded jointly to:
[**EDWIN MATTISON MC MILLAN**](1951a.html)
and
[**GLENN THEODORE SEABORG**](1951b.html)
for their discoveries in the chemistry of the transuranium elements.
**1950**
The prize was awarded jointly to:
[**OTTO PAUL HERMANN DIELS**](1950a.html)
and
[**KURT ALDER**](1950b.html)
for their discovery and development of the diene synthesis.
**1949**
[**WILLIAM FRANCIS GIAUQUE**](1949a.html)
for his contributions in the field of chemical thermodynamics, particularly concerning the behaviour of substances at extremely low temperatures.
**1948**
[**ARNE WILHELM KAURIN TISELIUS**](1948a.html)
for his research on electrophoresis and adsorption analysis, especially for his discoveries concerning the complex nature of the serum proteins.
**1947**
[**SIR ROBERT ROBINSON**](1947a.html)
for his investigations on plant products of biological importance, especially the alkaloids.
**1946**
The prize was divided, one half being awarded to:
[**JAMES BATCHELLER SUMNER**](1946a.html)
for his discovery that enzymes can be crystallized.
the other half jointly to
[**JOHN HOWARD NORTHROP**](1946b.html)
and
[**WENDELL MEREDITH STANLEY**](1946c.html)
for their preparation of enzymes and virus proteins in a pure form.
**1945**
[**ARTTURI ILMARI VIRTANEN**](1945a.html)
for his research and inventions in agricultural and nutrition chemistry, especially for his fodder preservation method.
**1944**
[**OTTO HAHN**](1944a.html)
for his discovery of the fission of
heavy nuclei.
**1943**
[**GEORGE DE HEVESY**](1943a.html)
for his work on the use of isotopes as tracers in the study of chemical processes.
1942-1940
The prize money was allocated to the Main Fund (1/3) and to the
Special Fund (2/3) of this prize section.
**1939**
[**ADOLF FRIEDRICH JOHANN BUTENANDT**](1939a.html)
for his work on sex hormones. (Caused by the authorities of
his country to decline the award but later received the
diploma and the medal).
and
[**LEOPOLD RUZICKA**](1939b.html)
for his work on polymethylenes and higher terpenes.
**1938**
[**RICHARD KUHN**](1938a.html)
for his work
on carotenoids and vitamins. (Caused by the authorities of his
country to decline the award but later received the diploma
and the medal.)
**1937**
The prize was divided equally between:
[**SIR WALTER NORMAN HAWORTH**](1937a.html)
for his investigations on carbohydrates and vitamin C.
and
[**PAUL KARRER**](1937b.html)
for his investigations on carotenoids, flavins and vitamins A and B2.
**1936**
[**PETRUS (PETER) JOSEPHUS WILHELMUS DEBYE**](1936a.html)
for his contributions to our knowledge of molecular structure through his investigations on dipole moments and on the diffraction of X-rays and electrons in gases.
**1935**
The prize was awarded jointly to:
[**FRÉDÉRIC JOLIOT**](1935a.html)
and
[**IRÈNE JOLIOT-CURIE**](1935b.html)
in recognition of their synthesis of new radioactive elements.
**1934**
[**HAROLD CLAYTON UREY**](1934a.html)
for his discovery of heavy hydrogen.
**1933**
The prize money was allocated to the Main Fund (1/3) and to the
Special Fund (2/3) of this prize section.
**1932**
[**IRVING LANGMUIR**](1932a.html)
for his discoveries and investigations in surface chemistry.
**1931**
The prize was awarded jointly to:
[**CARL BOSCH**](1931a.html)
and
[**FRIEDRICH BERGIUS**](1931b.html)
in recognition of their contributions to the invention and development of chemical high pressure methods.
**1930**
[**HANS FISCHER**](1930a.html)
for his researches into the constitution of haemin and chlorophyll and especially for his synthesis of haemin.
**1929**
The prize was divided equally between:
[**SIR ARTHUR HARDEN**](1929a.html)
and
[**HANS KARL AUGUST SIMON VON EULER-CHELPIN**](1929b.html)
for their investigations on the fermentation of sugar and fermentative enzymes.
**1928**
[**ADOLF OTTO REINHOLD WINDAUS**](1928a.html)
for the services rendered through his research into the constitution of the sterols and their connection with the vitamins.
**1927**
[**HEINRICH OTTO WIELAND**](1927a.html)
for his investigations of the
constitution of the bile acids and related substances.
**1926**
[**THE (THEODOR) SVEDBERG**](1926a.html)
for his work on disperse systems.
**1925**
[**RICHARD ADOLF ZSIGMONDY**](1925a.html)
for his demonstration of the heterogenous
nature of colloid solutions and for the methods he used, which have
since become fundamental in modern colloid chemistry.
**1924**
The prize money for 1924 was allocated to the Special Fund
of this prize section.
**1923**
[**FRITZ PREGL**](1923a.html)
for his invention of the method of micro-analysis of organic substances.
**1922**
[**FRANCIS WILLIAM ASTON**](1922a.html)
for his discovery, by means of his mass spectrograph, of isotopes, in a large number of non-radioactive elements, and for his enunciation of the whole-number rule.
**1921**
[**FREDERICK SODDY**](1921a.html)
, for his contributions to our knowledge of the chemistry of radioactive substances, and his investigations into the origin and nature of isotopes.
**1920**
[**WALTHER HERMANN NERNST**](1920a.html)
in recognition of his work in thermochemistry.
**1919**
The prize money for 1919 was allocated to the Special Fund of this prize section.
**1918**
[**FRITZ HABER**](1918a.html)
for the synthesis of ammonia from its elements.
1917-1916
The prize money for 1917-1916 was allocated to the Special
Fund of this prize section.
**1915**
[**RICHARD MARTIN WILLSTÄTTER**](1915a.html)
for his researches on plant pigments, especially chlorophyll.
**1914**
[**THEODORE WILLIAM RICHARDS**](1914a.html)
, in recognition of his accurate determinations of the atomic weight of a large number of chemical elements.
**1913**
[**ALFRED WERNER**](1913a.html)
in recognition of his work on the linkage of atoms in molecules by which he has thrown new light on earlier investigations and opened up new fields of research especially in inorganic chemistry.
**1912**
The prize was divided equally between:
[**VICTOR GRIGNARD**](1912a.html)
for the discovery of the so-called Grignard reagent, which in recent years has greatly advanced the progress of organic chemistry
and
[**PAUL SABATIER**](1912b.html)
for his method of hydrogenating organic compounds in the presence of finely disintegrated metals whereby the progress of organic chemistry has been greatly advanced in recent years.
**1911**
[**MARIE CURIE**](1911a.html),
née Marie Sklodowska,
in recognition of her services to the advancement of chemistry by the discovery of the elements radium and polonium, by the isolation of radium and the study of the nature and compounds of this remarkable element.
**1910**
[**OTTO WALLACH**](1910a.html)
in recognition of his services to organic chemistry and the chemical industry by his pioneer work in the field of alicyclic compounds.
**1909**
[**WILHELM OSTWALD**](1909a.html)
in recognition of his work on catalysis and for his investigations into the fundamental principles governing chemical equilibria and rates of reaction.
**1908**
[**LORD ERNEST RUTHERFORD**](1908a.html)
for his investigations into the disintegration of the elements, and the chemistry of radioactive substances.
**1907**
[**EDUARD BUCHNER**](1907a.html)
for his biochemical researches and his discovery of cellfree fermentation.
**1906**
[**HENRI MOISSAN**](1906a.html)
in recognition of the great services rendered by him in his investigation and isolation of the element fluorine, and for the adoption in the service of science of the electric furnace called after him.
**1905**
[**JOHANN FRIEDRICH WILHELM ADOLF VON BAEYER**](1905a.html)
in recognition of his services in the advancement of organic chemistry and the chemical industry, through his work on organic dyes and hydroaromatic compounds.
**1904**
[**SIR WILLIAM RAMSAY**](1904a.html)
in recognition of his services in the discovery of the inert gaseous elements in air, and his determination of their place in the periodic system.
**1903**
[**SVANTE AUGUST ARRHENIUS**](1903a.html)
in recognition of the extraordinary services he has rendered to the advancement of chemistry by his electrolytic theory of dissociation.
**1902**
[**HERMANN EMIL FISCHER**](1902a.html)
in recognition of the extraordinary services he has rendered by his work on sugar and purine syntheses.
**1901**
[**JACOBUS HENRICUS VAN'T HOFF**](1901a.html)
in recognition of the extraordinary services he has rendered by the discovery of the laws of chemical dynamics and osmotic pressure in solutions.
|
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<h1>USPaperMoney.Info</h1>
<p>Welcome to USPaperMoney.Info, home of everything you ever wanted to know
about U.S. currency. (Well, almost....)</p>
<p>The largest section of the site is devoted to the <a href="serials/">serial number
tables</a>. Here you can find almost-complete information on the overall serial
ranges for all small-size regular and star notes, Series 1928 to present. From 1976
to the present, the serial ranges are also broken down by month of production.</p>
<p><a href="groups/">Block and group lists</a> are available back to Series 1935E.
The group lists contain basically the same information as the serial tables, minus the
dates of production; but some collectors may find this format more useful, since the
exact serials printed in all those pesky pre-1995 star note runs are finally listed
out in detail.</p>
<!--
<strong style="color: orange; background-color: black;"> NEW! </strong>
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<p>Much of the serialling data is now available in <a
href="printable.html">printer-friendly</a> form, including all of the serial and group
lists from Series 1935D through 2009 in one large PDF file.</p>
<p>The <a href="history/">history of currency designs</a> gives an overview of the
development of U.S. paper money, from the first small-size notes in Series 1928 to the
latest "Kodachrome" redesign that concluded with the new colorised $100 note.</p>
<p>A section on <a href="sign/">signers of U.S. currency</a> has illustrations of
all of the Treasury signatures appearing on small-size notes.</p>
<p>The <a href="general/chron_s.html">chronology of small-size notes</a> may help in
matching up the various series and signature combinations with rough printing
dates.</p>
<p>A page on <a href="general/note.html">features of current notes</a> explains the
meaning of the various small numbers and letters scattered around the paper money
designs.</p>
<p>The <a href="link.html">links and references</a> page contains not only some of the
sources for the information on this site, but also some additional websites related to
the collecting of paper money.</p>
<p>Finally, there's a good long page of <a href="uhoh.html">unanswered questions</a>,
to which I'd appreciate any well-documented answers you may have.</p>
<p>Comments? Questions? Caught a typo? You can email me <a
href="mailto:webmaster@uspapermoney.info">here</a>.</p>
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USPaperMoney.Info
# USPaperMoney.Info
Welcome to USPaperMoney.Info, home of everything you ever wanted to know
about U.S. currency. (Well, almost....)
The largest section of the site is devoted to the [serial number
tables](serials/). Here you can find almost-complete information on the overall serial
ranges for all small-size regular and star notes, Series 1928 to present. From 1976
to the present, the serial ranges are also broken down by month of production.
[Block and group lists](groups/) are available back to Series 1935E.
The group lists contain basically the same information as the serial tables, minus the
dates of production; but some collectors may find this format more useful, since the
exact serials printed in all those pesky pre-1995 star note runs are finally listed
out in detail.
Much of the serialling data is now available in [printer-friendly](printable.html) form, including all of the serial and group
lists from Series 1935D through 2009 in one large PDF file.
The [history of currency designs](history/) gives an overview of the
development of U.S. paper money, from the first small-size notes in Series 1928 to the
latest "Kodachrome" redesign that concluded with the new colorised $100 note.
A section on [signers of U.S. currency](sign/) has illustrations of
all of the Treasury signatures appearing on small-size notes.
The [chronology of small-size notes](general/chron_s.html) may help in
matching up the various series and signature combinations with rough printing
dates.
A page on [features of current notes](general/note.html) explains the
meaning of the various small numbers and letters scattered around the paper money
designs.
The [links and references](link.html) page contains not only some of the
sources for the information on this site, but also some additional websites related to
the collecting of paper money.
Finally, there's a good long page of [unanswered questions](uhoh.html),
to which I'd appreciate any well-documented answers you may have.
Comments? Questions? Caught a typo? You can email me [here](mailto:webmaster@uspapermoney.info).
[![](http://counters.honesty.com/cgi-bin/honesty-counter.cgi?df=gen.16695268.00000)](http://www.andale.com)
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<title>Graphics Lab
Research projects
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<h1>
<img src="/logos/cglbanner_icon.gif" width=111 height=45 align=bottom alt=logo>
Research projects
<hr>
</h1>
</head>
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<p>
For Pat Hanrahan's current research, look at his
<a href=http://graphics.stanford.edu/~hanrahan/>home page</a>.
<p>
For Ron Fedkiw's research, look at his
<a href=http://graphics.stanford.edu/~fedkiw/>home page</a>.
<p>
For Leo Guibas's research, look at his
<a href=http://geometry.stanford.edu/>lab page</a>.
<p>
For Vladlen Koltun's research, look at his
<a href="http://vladlen.info">home page</a>.
<p>
For Marc Levoy's projects, click on one of the links below:
<p>
<table>
<tr>
<td align=left width=375>
<p>
<a href="lightfield/">
<img src=images/coherence_preview-icon.gif height=50>
<img src=images/ren-ng-icon.gif height=50>
<br>
Light fields and computational photography</a>
<p>
<a href="lfmicroscope/">
<img src=images/crayons3-cc-smallicon.gif height=50>
<br>
Stanford Light Field Microscope Project</a>
</td>
<td align=left width=375>
<p>
<a href="camera-2.0/">
<img src=images/nokia-n95-on-black-h50.jpg height=50>
<img src=images/burghers-calais-cebalssh-h50.jpg height=50>
<br>
Camera 2.0</a>
</td>
</tr>
</table>
<p>
<hr>
<h3>
Inactive research projects (by various faculty)
</h3>
<table>
<tr>
<td align=left width=375>
<p>
<a href="volume/">
<img src=images/volume-hologram.gif height=50>
<br>
Volume rendering</a>
<p>
<a href="spreadsheets/">
<img src=images/spreadsheets-smallfax.gif height=50>
<br>
Spreadsheets for images</a></li>
<p>
<a href="faxing/">
<img src=images/faxing-sixhappys.gif height=50>
<br>
Project to build a 3D fax machine</a>
<p>
<a href="compression/">
<img src=images/compression-smallfig3.gif height=50>
<br>
Compression of synthetic images</a></li>
<p>
<a href="texture/">
<img src=texture/texture_o_icon.jpg height=50>
<br>
Texture Analysis and Synthesis</a>
<p>
<a href="//accademia.stanford.edu/mich/">
<img src=images/digital_michelangelo.gif height=50>
<br>
The Digital Michelangelo Project</a>
<p>
<a href="//accademia.stanford.edu/forma-urbis/">
<img src=images/forma-urbis-a2140-010g-0-c.gif height=50>
<br>
Digital Forma Urbis Romae Project (CS pages)</a> or
<br>
<a href="//formaurbis.stanford.edu/index.html">
Digital Forma Urbis Romae Project (Classics pages)</a>
<p>
<a href="array/">
<img src=images/fromLRC-wide-cbal-ssh.gif height=50>
<br>
The Stanford Multi-Camera Array</a>
<p>
<a href="RWB/">
<img src=images/rwb-bench.gif height=50>
<br>
Responsive workbench</a>
<p>
<a href="flashg/">
<img src=images/flashg_banner_smallicon.gif height=50>
<br>
FLASH graphics systems</a>
<p>
<a href="multigraphics/">
<img src=images/multigraphics-wiregl_logo.gif height=50>
<br>
MultiGraphics</a>
</td>
<td align=left width=375>
<p>
<a href="cityblock/">
<img src="images/castro_all_trees-with-rays-w1000-smallicon.gif" height=50>
<br>
Stanford CityBlock Project</a>
<p>
<a href="dli/">
<img src=images/dli_banner.gif height=50>
<br>
Creating digital archives of 3D artworks</a>
<p>
<a href="gantry/">
<img src=images/glogo-icon.gif height=50>
<br>
The Stanford Spherical Gantry</a>
<p>
<a href="imtv/">
<img src=images/imtv-panorama.gif height=50>
<br>
Stanford Immersive Television Project</a>
<p>
<a href="cuneiform/">
<img src=images/cuneiform-collage.gif height=50>
<br>
Cuneiform Tablet Visualization Project</a></li>
<p>
<a href="movement/">
<img src=images/movement_logo.gif height=50>
<br>
Movement Project</a>
<p>
<a href="shading/">
<img src=images/shading_logo.gif height=50>
<br>
Real-time programmable shading</a>
<p>
<a href="polaris/">
<img src=polaris/logo-on-white-s.gif height=50>
<br>
Polaris: Interactive database visualization</a>
<p>
<a href="rivet/">
<img src=images/rivet-polaris1_icon.gif height=50>
<br>
RIVET: Visualization of computer systems</a>
<p>
<a href="rendering/">
<img src=images/rendering-diana_bssrdf.gif height=50>
<br>
Rendering algorithms</a>
<p>
<a href="iwork/old/">
<img src=images/iroom.gif height=50>
<br>
Interactive Workspaces</a>
</td>
</tr>
</table>
<p>
<hr>
<p>
A <a href="/papers/"> list of technical publications</a>, with abstracts and
pointers to additional information, is also available.
<br>
Or you can
return to our <a href="/">home page</a>.
<p>
<hr>
Last update:
March 27, 2015 12:46:51 PM
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<b><a href="/copyright.html">© 1994-2023
Stanford Computer Graphics Laboratory</a></b>
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Graphics Lab
Research projects
#
logo
Research projects
---
For Pat Hanrahan's current research, look at his
[home page](http://graphics.stanford.edu/~hanrahan/).
For Ron Fedkiw's research, look at his
[home page](http://graphics.stanford.edu/~fedkiw/).
For Leo Guibas's research, look at his
[lab page](http://geometry.stanford.edu/).
For Vladlen Koltun's research, look at his
[home page](http://vladlen.info).
For Marc Levoy's projects, click on one of the links below:
| | |
| --- | --- |
|
[Light fields and computational photography](lightfield/)
[Stanford Light Field Microscope Project](lfmicroscope/)
|
[Camera 2.0](camera-2.0/)
|
---
###
Inactive research projects (by various faculty)
| | |
| --- | --- |
|
[Volume rendering](volume/)
[Spreadsheets for images](spreadsheets/)
[Project to build a 3D fax machine](faxing/)
[Compression of synthetic images](compression/)
[Texture Analysis and Synthesis](texture/)
[The Digital Michelangelo Project](//accademia.stanford.edu/mich/)
[Digital Forma Urbis Romae Project (CS pages)](//accademia.stanford.edu/forma-urbis/) or
[Digital Forma Urbis Romae Project (Classics pages)](//formaurbis.stanford.edu/index.html)
[The Stanford Multi-Camera Array](array/)
[Responsive workbench](RWB/)
[FLASH graphics systems](flashg/)
[MultiGraphics](multigraphics/)
|
[Stanford CityBlock Project](cityblock/)
[Creating digital archives of 3D artworks](dli/)
[The Stanford Spherical Gantry](gantry/)
[Stanford Immersive Television Project](imtv/)
[Cuneiform Tablet Visualization Project](cuneiform/)
[Movement Project](movement/)
[Real-time programmable shading](shading/)
[Polaris: Interactive database visualization](polaris/)
[RIVET: Visualization of computer systems](rivet/)
[Rendering algorithms](rendering/)
[Interactive Workspaces](iwork/old/)
|
---
A [list of technical publications](/papers/), with abstracts and
pointers to additional information, is also available.
Or you can
return to our [home page](/).
---
Last update:
March 27, 2015 12:46:51 PM
**[© 1994-2023
Stanford Computer Graphics Laboratory](/copyright.html)**
| http://graphics.stanford.edu/projects/ |
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<p>This just in!<font size="-1"><br>
</font></p>
<p><font size="-1">JAKKS PACIFIC figures are in TARGET AND WALMART NOW, as well as 5 Below (sometimes) 06.19.23</font></p>
<p><font size="-1" color="#ee0000">GOOD NEWS</font><font size="-1">: GE Entertainment Has Gotten Back the Sonic license in 2019! Older items can be seen at: <a href="StoreSonic/PlushStore.html">GE Sonic Plushes</a> </font></p>
<p><font size="-1">BEWARE of FAKE SONIC AMIIBO figures - ONLY Sonic is official - any other Sonic character is NOT a real Amiibo = don't buy it.<br>
</font><font size="-1">FAKE FANG warning. Fake Fang/Knack plushes are all over ebay. See the <a href="BootlegFakes/AvoidBootlegs2.html">Bootleg Guide</a> on how to avoid him before you bid!<br>
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<font color="#cc3366">Announcements & The Latest Updates<br>
</font><font size="-1" color="#cc3366">Last Update of the Year 12.26.23<br>
</font><font size="-1" color="#330000">It's the last update of 2023, so take a look into the next year early with <a href="USAPages/USAFigures/JakksPacificFigures/5InchFigures/JakksPacific5InchFigures5.html">New Badnick Figure</a>, then see a cool <a href="FanEvents/Japan%20Events/JapanSonicPlaces5.html">Mall Display</a>, some <a href="USAPages/USAFoods/USAFoods4.html">Amy Energy Powder</a>, more <a href="ChristmasHoliday/HolidayChristmas.html">Christmas Ornaments on the NEW Christmas Page</a>, a closer look at the <a href="USAPages/USAElectronics/SonicElectronics11.html">Cable Guys Shadow</a> & a <a href="DisplayFigures/DisplayFigures13.html">Japan Only Display Figure</a>.<br>
</font><font size="-1" color="#cc3366">Xmas Update 12.12.23<br>
</font><font size="-1" color="#330000">This update brings a timely new page: <a href="ChristmasHoliday/HolidayChristmas.html">Sonic Christmas Gear</a>. There are also things to add to your list such as <a href="USAPages/USAFigures/JakksPacificFigures/5InchFigures/JakksPacific5InchFigures5.html">Super Silver Figure</a>, a <a href="USAPages/SonicUSARandom5.html">Strange Duck</a>, three new Sonic <a href="SonicPrime/SonicPrimeItems1.html">Prime Figures</a>, and a <a href="MovieSonic/MovieMerchandise5.html">First4Figures Statue</a>. There's also a <a href="FanEvents/WorldEvents/SonicWorldEvents2.html">Mall Display Super Stars</a> to see while you shop.<br>
</font><font size="-1" color="#cc3366">Extra Update 12.07.23<br>
</font><font size="-1" color="#330000">Trying to make up for missed updates. There is a <a href="USAPages/USAPlushes/SonicPlushesUSA20.html">Stickerbomb Plush</a>, a look at <a href="DisplayFigures/DisplayFigures13.html">Buildable Knuckles</a>, then <a href="MovieSonic/MovieMerchandise4.html">Build a Bear releases an Odd Super Sonic</a>, there are 3 new <a href="USAPages/USAElectronics/SonicElectronics11.html">Sonic Electronics Items</a>, and a look at NEW (good news) <a href="USAPages/USAFigures/JakksPacificFigures/5InchFigures/JakksPacific5InchFigures5.html">Jakks Pacific Packaging</a>, then an <a href="USAPages/SonicRetailDisplay3.html">Ad That's Old & New</a>, and finally a <a href="SonicPrime/SonicPrimeItems1.html">Prime Figure closer look</a>.<br>
</font><font size="-1" color="#cc3366">Not Enough of the Update 12.05.23<br>
</font><font size="-1" color="#330000">Just a normal update (yea normally late ugh) but it still has 6 things and some ok variety because <a href="FrancePages/FrancePage3.html">France Ceramic Items</a> & <a href="BrazilPages/BrazilItems2.html">Brazil Superstars Pin</a>. There's also some <a href="USAPages/WinterWear/SonicWinterWear13.html">Box Lunch Winter Wear</a>, 2 <a href="USAPages/USAClothesRecent5/USAClothesRecent42.html">Box Lunch Jerseies</a>, & <a href="USAPages/JewelrySonic.html">King Ice</a> is really glamming it up this week as well. But what's an <a href="USAPages/USAHygene/SonicHygene3.html">Adventure Toothbrush</a>? (answer isnt here)<br>
</font><font size="-1" color="#cc3366">Return of the Update 11.15.23<br>
</font><font size="-1" color="#330000">As expected, the last one skipped but the update is back, and with more stuff. There's a <a href="FrancePages/FrancePage3.html">France Fleece</a>, a better look at <a href="USAPages/USAFigures/JakksPacificFigures/SmallLineFigures/JakksPacificSmallLineFigures5.html">Chopper Fish</a> & <a href="USAPages/USAFigures/JakksPacificFigures/5InchFigures/JakksPacific5InchFigures5.html">New Gold Series Figure</a>, and a new <a href="USAPages/USAPlushes/SonicPlushesUSA20.html">Lay Down Plush</a>. Then see a <a href="USAPages/USAHomeDecor/USAHomeDeco2/HomeDecorUSA21.html">Sonic Fridge</a>? (Its real!), <a href="USAPages/WinterWear/SonicWinterWear12.html">2 Sweat Shirts</a> for the season, a <a href="USAPages/USAClothesRecent5/USAClothesRecent42.html">Box Lunch Shirt</a>, & some <a href="JapanPages/JapanSonicRandom4.html">Guitar Picks</a> too.<br>
</font><font size="-1" color="#cc3366">Early Update 10.26.23<br>
</font><font size="-1" color="#330000">This update is early because the next one will be skipped. There are <a href="UKPages/UK%20Photos/UKHomeDecor/UKHousehold6.html">3 new Bed Items</a> to see in the UK area, then a <a href="USAPages/USAFigures/JakksPacificFigures/SmallLineFigures/JakksPacificSmallLineFigures5.html">New Box For Chao</a>, celebrate Superstars with a <a href="MiscItems/SonicMagazines8.html">Famitsu Cover</a>, then see <a href="USAPages/USKeychainsPins/SonicPinsKeychains8.html">Just Funky's Pinboard</a>, an <a href="USAPages/USAClothesRecent5/USAClothesRecent42.html">Ice Cream Theme Tee</a> & 2 new <a href="USAPages/SonicUSARandom6.html">Hallmark Sonic Ornaments</a>.<br>
</font><font size="-1" color="#cc3366">2 Of Most Things Update 10.22.23<br>
</font><font size="-1" color="#330000">This update is bigger than usual too so there's more to enjoy like <a href="USAPages/USKeychainsPins/SonicPinsKeychains8.html">2 Glitter Pins</a>, first look at <a href="USAPages/USAPlushes/SonicPlushesUSA20.html">Just Funky Plush</a>, a <a href="USAPages/USAHomeDecor/USAHomeDeco2/HomeDecorUSA20.html">Coin Bank</a>, and then <a href="USAPages/PartySupplies/SonicPartySupplies5.html">2 Party Supplies</a>, <br>
<a href="USAPages/USAElectronics/SonicElectronics11.html">ASRock PC Motherboard & a random Phone Stand</a>, plus the <a href="FanEvents/Japan%20Events/JapanSonicPlaces5.html">Fuji Q Highland Sonic Place</a>. Then there's a <a href="UKPages/UK%20Photos/UKFoods/UKSonicFoods2.html">Celebration Cake</a> & <a href="USAPages/USAClothesRecent5/USAClothesRecent42.html">2 Sakura Tees</a>.<br>
</font><font size="-1" color="#cc3366">On Time 8 Item Update 10.17.23<br>
</font><font size="-1" color="#330000">The focus here is mostly on new stuff so see a new company <a href="USAPages/SwimGear/SwimGearSonic1.html">Mighty Mojo Pool Float</a> AND <a href="USAPages/PartySupplies/SonicPartySupplies5.html">Party Supplies Sonic</a>. Then there's the <a href="USAPages/USKeychainsPins/SonicPinsKeychains8.html">Halloween Costume Pirate Pin</a>, a look at <a href="UKPages/UKElectronics3.html">Pix n' Love Origins Bonus</a>, the final of <a href="USAPages/SonicUSARandom6.html">Flying Heroes Toy</a>, some <a href="USAPages/USAHomeDecor/USAHomeDeco2/HomeDecorUSA20.html">Funky Pillow Faces</a>, old <a href="AustraliaPages/AustraliaItems9.html">Zega Zone Australia Items</a> & <a href="USAPages/USAElectronics/SonicElectronics11.html">Power A Controller</a>. <br>
</font><font size="-1" color="#cc3366">A Bit Late & More Stuff Update 10.09.23<br>
</font><font size="-1" color="#330000">As is tradition in October, there's a <a href="USAPages/HalloweenUSA/HalloweenUSA2.html">Halloween Costume</a> to see first, then some <a href="USAPages/USKeychainsPins/SonicPinsKeychains8.html">NYCC Pins</a>, and a <a href="DisplayFigures/DisplayFigures13.html">New Funko Soda</a>. Then see what <a href="BootlegFakes/AvoidingBootlegs37.html">AI Art might do</a>, GE's New <a href="USAPages/USAPlushes/SonicPlushesUSA20.html">Amy Dol</a>l, a better look at <a href="USAPages/USAFigures/JakksPacificFigures/5InchFigures/JakksPacific5InchFigures5.html">Boxed Infinite Jackal</a>, NKOK re-releases the <a href="USAPages/NKOKSonicFigures.html">Tails All Star Racer</a> and finally a <a href="USAPages/USAClothesRecent5/USAClothesRecent42.html">Cool New Tee</a>.<br>
</font><font size="-1" color="#330000"></font>
<p><font size="-1" color="#330000"><a href="TextPages/WhyNoAdblock.html">Don't Use Ad Block on SonicGear</a> mini-article also gets an update with pictures to help explain it.<br>
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<td width="354" height="64" colspan="18" valign="top" align="left" xpos="400"><img src="StoreSonic/GearStoreHeaderBar.jpg" alt="" height="45" width="350" usemap="#GearStoreHeaderBara9ac1d4b" border="0"></td>
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<td width="1" height="64"><spacer type="block" width="1" height="64"></td>
</tr>
<tr height="49">
<td class="dsR288 dsR172" content="content" csheight="451" width="368" height="467" colspan="20" rowspan="2" valign="top" xpos="400"><a href="StoreSonic/SonicStore1.html">Sonic Gear Store! Now you can buy Sonic Stuff!</a><br>
<br>
<a href="StoreSonic/KeychainsPinsStore.html">Sonic K</a><a href="StoreSonic/KeychainsPinsStore.html">eychains Pins & Straps<br>
</a><a href="StoreSonic/PartySuppliesStore.html">Sonic Party Supplies</a><a href="StoreSonic/KeychainsPinsStore.html"><br>
</a><a href="StoreSonic/FigureStore.html">Sonic Action Figures & Display Figures</a><a href="StoreSonic/KeychainsPinsStore.html"><br>
</a><a href="StoreSonic/PlushStore.html">Sonic Plush Dolls<br>
</a><a href="StoreSonic/VideoStore.html">Sonic Video DVD Sets<br>
</a><a href="StoreSonic/VideoEpisodeStore.html">Sonic Video Episodes<br>
</a><a href="StoreSonic/ClothingStore.html">Sonic Clothing Store<br>
</a><a href="StoreSonic/ClothingStore2.html">Sonic Clothing Store 2: Tees Galore!<br>
</a><a href="StoreSonic/ClothingStore3.html">Sonic Clothing Store 3: Nearly Sold-Out Stuff<br>
</a><a href="StoreSonic/ClothingWinter.html">Sonic Winter Clothing Store<br>
</a><a href="StoreSonic/AccessoriesStore.html">Sonic Accessories Store<br>
</a><a href="StoreSonic/BookStoreSonic.html">Sonic Books Store<br>
</a><a href="StoreSonic/BookStoreArchieSonic.html">Archie Sonic Comic Book Store</a><a href="StoreSonic/BookStoreSonic.html"><br>
</a><a href="StoreSonic/HomeDecorStore.html">Sonic Posters & Wall Scrolls<br>
</a><a href="StoreSonic/HomeDecorStore2.html">Sonic Home Decor 2</a><br>
<a href="StoreSonic/KitchenGlassware.html">Sonic Kitchen & Glassware Store<br>
</a><a href="StoreSonic/HatSonicStore.html">Sonic Hats Buying Area<br>
</a><a href="StoreSonic/HalloweenCostumeStore.html">Sonic Halloween Costume Cosplay & Accessory Store<br>
</a><a href="StoreSonic/MusicStore.html">Sonic Music & Soundtracks Store<br>
</a><a href="StoreSonic/BagStoreSonic.html">Sonic Bag School Bag & Lunch Carrier Store<br>
</a><a href="StoreSonic/BoomPartyStore.html">Sonic BOOM Store: Party Supplies</a></td>
<td width="26" height="467" colspan="5" rowspan="2"></td>
<td width="1" height="49"><spacer type="block" width="1" height="49"></td>
</tr>
<tr height="418">
<td width="34" height="594" colspan="7" rowspan="3"></td>
<td class="dsR313 dsR188" content="content" csheight="577" width="319" height="594" colspan="12" rowspan="3" valign="top" xpos="34"><a href="USAPages/USAFigures/USAFiguresHUBPage.html">USA Sonic Action Figures HUB Page</a><a href="USAPages/USASonicFigures.html"><br>
USA Sonic the Hedgehog Action Figures</a><br>
<a href="USAPages/USAFigures/TomyFigures/TomySonicFigures1.html">Tomy Sonic Action Figures<font size="-1"> </font></a><font size="-1"><a href="USAPages/GiantTalkingFigures.html"><br>
</a><a href="USAPages/USAFigures/TomyFigures/TomySonicFigures2.html">Tomy Sonic Action Figures 2</a><a href="USAPages/GiantTalkingFigures.html"><br>
</a><a href="USAPages/USAFigures/TomyFigures/TomySonicClassicFigures.html">Tomy Classic Sonic Action Figures</a><a href="USAPages/GiantTalkingFigures.html"><br>
</a></font><font size="+1"><a href="USAPages/ReSaurusFigures.html">ReSaurus Sonic Action Figures</a><br>
<a href="USAPages/ToyIslandFigures.html">Toy Island Sonic Action Figures</a><br>
</font><font size="-1"><a href="USAPages/ToyIslandFigures2.html">Toy Island Series II Action Figures</a> - <a href="USAPages/ToyIslandFE.html">Figures & Emeralds</a><a href="USAPages/ToyIslandFigures2.html"><br>
</a><a href="USAPages/ToyIslandSF.html">Space Fighters</a><a href="USAPages/ToyIslandFigures2.html"> </a>*<a href="USAPages/ToyIslandFigures2.html"> </a><a href="USAPages/ToyIslandMF.html">Metal Force</a> *<a href="USAPages/ToyIslandFigures2.html"> </a><a href="USAPages/ToyIslandMB.html">Mega Bot </a>*<a href="USAPages/ToyIslandFigures2.html"> </a><a href="USAPages/SuperPosers.html">Super Pose</a><a href="USAPages/ToyIslandFigures2.html">rs</a><br>
</font><a href="USAPages/BendyFigures.html">Bendy Sonic Figures</a><br>
<a href="USAPages/GiantTalkingFigures.html">Giant Talking Action Figures</a><font size="-1"><a href="USAPages/GiantTalkingFigures.html"><br>
</a></font><a href="USAPages/USAFigures/JakksPacificFigures/JakksPacificActionFigures.html">JakksPacific Sonic Action Figures<font size="-1"><br>
</font></a><font size="-1"><a href="USAPages/USAFigures/JakksPacificFigures/JakksPacificBendyFigures.html">Jakks Pacific Sonic Bendy Bendable Figures<br>
</a><a href="USAPages/USAFigures/JakksPacificFigures/JakksPacificBendyFigures2.html">Jakks Pacific Bendy Bendable Sonic Figures 2<br>
</a><a href="USAPages/USAFigures/JakksPacificFigures/JakksPacificSmallFigures.html">Jakks Pacific Small Sonic Figures<br>
</a></font><font size="-1" color="#330000"><a href="USAPages/USAFigures/JakksPacificFigures/JakksPacificDeluxeFigures.html">Jakks Pacific Deluxe Figures<br>
</a></font><font size="-1"><a href="USAPages/JazwaresFigures.html">Jazwares Action Figures<br>
</a><a href="USAPages/JazwaresSBK.html">Jazwares Sonic Black Knight Figures<br>
</a><a href="USAPages/JazwaresSBK2.html">Jazwares Sonic Black Knight Figures 2<br>
</a><a href="USAPages/JazwaresJUVIs.html">Jazwares Action Figures 3 JUVIs<br>
</a><a href="USAPages/JazwaresGeneral.html">Jazwares General Sonic Action Figures<br>
</a><a href="USAPages/JazwaresSuperPosers.html">Jazwares Super Poser Sonic Action Figures<br>
</a><a href="USAPages/JazwaresSuperPosers2.html">Jazwares Super Poser Sonic Action Figures 2<br>
</a><a href="USAPages/JazwaresSmallSonic.html">Jazwares Small 3 inch Action Figures<br>
</a><a href="USAPages/JazwaresSmallSonic2.html">Jazwares Small 3 inch Action Figures 2<br>
</a><a href="USAPages/JazwaresSmallSonic3.html">Jazwares Small Line 3<br>
</a><a href="USAPages/JazwaresSmallSonic4.html">Jazwares Small Line 4<br>
</a><a href="USAPages/JazwaresSmallSonic5.html">Jazwares Small Line 5<br>
</a><a href="USAPages/JazwaresSmallSonic6.html">Jazwares Smal Line 6<br>
</a><a href="USAPages/JazwaresRacers.html">Jazwares Sonic Racers Action Figures<br>
</a><a href="USAPages/JazwaresRacers2.html">Jazwares Sonic Racers Figures 2<br>
</a><a href="USAPages/JazwaresRacers3.html">Jazwares Allstars Transformed Racers Figures<br>
</a><a href="USAPages/JazwaresGenClassic.html">Jazwares CLASSIC Generations Style Sonic Figures<br>
</a><a href="USAPages/JazwaresGenModern.html">Jazwares MODERN Generations Style Sonic Figures<br>
</a><a href="USAPages/JazwaresRiders.html">Jazwares Sonic Riders / FreeRiders Figures<br>
</a><a href="USAPages/JazwaresUnleashed.html">Jazwares Unleashed / Werehog</a></font></td>
<td width="47" height="418" colspan="3"></td>
<td width="1" height="418"><spacer type="block" width="1" height="418"></td>
</tr>
<tr height="77">
<td width="50" height="77" colspan="5"></td>
<td width="351" height="77" colspan="16" valign="top" align="left" xpos="403"><img class="dsR333 dsR196" src="Headers-Buttons/OtherTop.jpg" alt="Other Sonic the Hedgehog Collectibles" height="45" width="350" usemap="#OtherTop7687d77" border="0"></td>
<td width="40" height="77" colspan="7"></td>
<td width="1" height="77"><spacer type="block" width="1" height="77"></td>
</tr>
<tr height="99">
<td width="66" height="99" colspan="9"></td>
<td class="dsR335 dsR193" content="content" csheight="960" width="256" height="977" colspan="9" rowspan="5" valign="top" xpos="419"><a href="ComicsPages/ComicsMain.html">Sonic Comics</a><br>
<a href="MiscItems/SonicMagazineScans.html">Magazine Shots & Items<br>
</a><font size="-1"><a href="MiscItems/Sonic%20Magazines2.html">Sonic Magazines 2<br>
</a><a href="MiscItems/SonicMagazines3.html">Sonic Magazines 3</a></font><br>
<font size="-1"><a href="MiscItems/SonicMagazines4.html">Sonic Magazines 4<br>
</a><a href="MiscItems/SonicMagazines5.html">Sonic Magazines 5</a><br>
<a href="MiscItems/SonicMagazines6.html">Sonic Magazines 6<br>
</a><a href="MiscItems/SonicMagazines7.html">Sonic Magazines 7<br>
</a></font><a href="MiscItems/MagazineReadAPage.html">Magazine Read A Page<br>
</a><a href="ShowPages/MediaItems/ShowMediaHUB.html">Sonic TV Shows</a><br>
<a href="GamesPages/GamesMain.html">Sonic Games<br>
</a><a href="FanItems/FanItemsHub.html">Sonic Fan Items<br>
</a><a href="USAPages/SonicFastFood.html">Fast Food Sonic USA</a><a href="FanItems/FanItems.html"><br>
</a><a href="InternationalPhotos/InternationalFastFood.html">Fast Food Sonic International<br>
</a><font size="-1"><a href="InternationalPhotos/InternationalFastFood2.html">Fast Food Sonic International Page 2<br>
</a></font><a href="Music/SonicMusic.html">Sonic Music International<br>
</a><a href="Music/SonicMusic2.html"><font size="-1">Sonic Music 2</font></a><a href="Music/SonicMusic.html"><br>
</a><a href="Music/SonicMusic3.html"><font size="-1">Sonic Music 3</font></a><a href="Music/SonicMusic.html"><br>
</a><a href="Music/SonicMusic4.html"><font size="-1">Sonic Music 4</font></a><a href="Music/SonicMusic.html"><br>
</a><font size="-1"><a href="Music/SonicMusic5.html">Sonic Music 5<br>
</a></font><a href="Music/SonicDancePower.html">Sonic Dance Power<br>
</a><a href="Prototypes/SonicPrototypes.html">Sonic The Hedgehog Prototype Items<br>
</a><span class="ds2"><a href="Prototypes/SonicPrototypes2.html"><font size="-3">Sonic Prototypes 2<br>
</font></a><a href="Prototypes/SonicPrototypes3.html"><font size="-3">Sonic Prototypes 3</font><br>
</a><font size="-3"><a href="Prototypes/SonicPrototypes4.html">Sonic Prototypes 4</a></font><a href="Prototypes/SonicPrototypes3.html"><br>
</a><font size="-3"><a href="Prototypes/SonicPrototypes5.html">Sonic Prototypes 5<br>
</a><a href="Prototypes/SonicPrototypes6.html">Sonic Prototypes 6<br>
</a><a href="Prototypes/SonicPrototypes7.html">Sonic Prototypes 7<br>
</a><a href="Prototypes/SonicPrototypes8.html">Sonic Prototypes 8<br>
</a><a href="Prototypes/SonicPrototypes9.html">Sonic Prototypes 9<br>
</a></font></span><a href="ArcadeMachines/ArcadeSonic.html">Sonic The Hedgehog Arcade Machines<br>
</a><font size="-1"><a href="ArcadeMachines/ArcadeSonic2.html">Sonic Arcade Machines 2<br>
</a><a href="ArcadeMachines/ArcadeSonic3.html">Sonic Arcade Machines 3<br>
</a><a href="ArcadeMachines/ArcadeSonic4.html">Sonic Arcade Machines 4<br>
</a></font><a href="DisplayFigures/DisplayFigures.html">Sonic the Hedgehog Display Figures<br>
</a><font size="-1"><a href="DisplayFigures/DisplayFigures2.html">Sonic the Hedgehog Display Figures 2<br>
</a><a href="DisplayFigures/DisplayFigures3.html">Sonic the Hedgehog Display Figures 3<br>
</a><a href="DisplayFigures/DisplayFigures4a.html">Sonic the Hedgehog Display Figures 4<br>
</a></font><a href="Statues/SonicStatues.html">Sonic the Hedgehog Statues<br>
</a><a href="Statues/SonicStatues2.html"><font size="-1">Sonic Statues 2</font></a><a href="Statues/SonicStatues.html"><br>
</a><a href="ParodyItems/SonicParody.html">Sonic the Hedgehog Parody Items<br>
</a><font size="-1"><a href="ParodyItems/SonicParody2.html">Sonic Parody Items 2</a></font><a href="ParodyItems/SonicParody.html"><br>
</a><font size="-1"><a href="ParodyItems/SonicParody3.html">Sonic Parody Items 3</a></font><a href="ParodyItems/SonicParody.html"><br>
</a><a href="Cameos/CameosSonic.html">Sonic Cameo Appearances<br>
</a><font size="-1"><a href="Cameos/CameosSonic2.html">Sonic Cameos 2<br>
</a><a href="Cameos/CameosSonic3.html">Sonic Cameos 3<br>
</a><a href="Cameos/CameosSonic4.html">Sonic Cameos 4<br>
</a><a href="Cameos/CameosSonic5.html">Sonic Cameos 5<br>
</a></font><a href="VirtualItems/VirtualSonicItems.html">Virtual Sonic Items<br>
</a><a href="InternationalUnknown.html">International Unknown Sonic Items<br>
</a><a href="HighEnd/HighEnd.html">High End Sonic Items<br>
</a><a href="GachaFigures/GachaFigures.html">Sonic Gacha / Gashapon Figures<br>
</a><a href="FancyBags/ShowBags1.html">Sonic Show Bags / Fancy Bags<br>
</a><a href="SuspiciousItems/SuspiciousItems.html">Suspicious / Red Herring Items<br>
</a><font size="-1"><a href="SuspiciousItems/SuspiciousItems2.html">Suspicious / Red Herring Items 2</a></font></td>
<td width="119" height="977" colspan="10" rowspan="5"></td>
<td width="1" height="99"><spacer type="block" width="1" height="99"></td>
</tr>
<tr height="56">
<td width="1" height="56"></td>
<td width="384" height="56" colspan="19" valign="top" align="left" xpos="1"><img class="dsR312 dsR186" src="Headers-Buttons/AWTop.jpg" alt="Sonic the Hedgehog around the world" height="39" width="355" usemap="#AWTop6d44252" border="0"></td>
<td width="34" height="56" colspan="8"></td>
<td width="1" height="56"><spacer type="block" width="1" height="56"></td>
</tr>
<tr height="310">
<td width="25" height="1173" colspan="5" rowspan="7"></td>
<td class="dsR310 dsR184" content="content" csheight="299" width="248" height="310" colspan="9" valign="top" xpos="25"><a href="AustraliaPages/AustraliaItems.html">Australia Sonic the Hedgehog<br>
</a><font size="-1"><a href="AustraliaPages/AustraliaItems2.html">Australia Sonic Page 2<br>
</a><a href="AustraliaPages/AustraliaItems3.html">Australia Sonic Page 3</a></font><br>
<font size="-1"><a href="AustraliaPages/AustraliaItems4.html">Australia Sonic Page 4<br>
</a><a href="AustraliaPages/AustraliaItems5.html">Australia Sonic Page 5<br>
</a><a href="AustraliaPages/AustraliaItems6.html">Australia Sonic Page 6<br>
</a><a href="AustraliaPages/AustraliaItems7.html">Australia Sonic Page 7<br>
</a><a href="AustraliaPages/AustraliaSonicPlush1.html">Australia Sonic Plush Dolls 1<br>
</a><a href="AustraliaPages/AustraliaSonicPlush2.html">Australia Sonic Plush Dolls 2<br>
</a><a href="AustraliaPages/Australia%20Photos/ElectronicsAustralia/ElectronicsAustralia.html">Australia Sonic Electronics<br>
</a><a href="AustraliaPages/AustraliaAccessory.html">Australia Sonic Accessories<br>
</a></font><a href="FrancePages/FrancePage.html">France Sonic the Hedgehog</a><br>
<font size="-1"><a href="FrancePages/FrancePage2.html">France Sonic the Hedgehog Page 2<br>
</a><a href="FrancePages/FrancePage3.html">France Sonic the Hedgehog Page 3<br>
</a></font><a href="GermanyPages/GermanItems.html">Germany Sonic the Hedgehog</a><br>
<a href="SaudiArabiaPage/SArabiaPage.html">Saudi Arabia Sonic the Hedgehog</a><br>
<a href="SpainPages/SpainPage.html">Spain Sonic The Hedgehog<br>
</a><a href="InternationalUnknown.html">Unknown International Sonic Items</a></td>
<td width="146" height="310" colspan="14"></td>
<td width="1" height="310"><spacer type="block" width="1" height="310"></td>
</tr>
<tr height="201">
<td content csheight="191" width="241" height="201" colspan="8" valign="top" xpos="25"><a href="NetherlandsPages/NetherlandsItems.html">Netherlands Sonic The Hedgehog<br>
</a><a href="IsraelPages/IsraelPage.html">Israel Sonic The Hedgehog Items<br>
</a><a href="PortugalPages/PortugalSonic1.html">Portugal Sonic the Hedgehog Items<br>
</a><a href="KoreaPages/KoreaPage1.html">Korea Sonic The Hedgehog Items<br>
</a><a href="FinlandPages/FinlandSonicItems.html">Finland Sonic The Hedgehog Items<br>
</a><a href="CanadaPages/CanadaSonicItems.html">Canada Sonic The Hedgehog Items<br>
</a><a href="BrazilPages/BrazilItems1.html">Brazil Sonic The Hedgehog Items<br>
</a><a href="ChinaPages/ChinaSonicItems1.html">China Sonic the Hedgehog Items<br>
</a><a href="EuropeGeneral/EuropeGeneral.html">Europe General Sonic Items<br>
</a><a href="EuropeGeneral/EuropeGeneral1.html"><font size="-1">Europe General 2</font></a></td>
<td width="153" height="201" colspan="15"></td>
<td width="1" height="201"><spacer type="block" width="1" height="201"></td>
</tr>
<tr height="311">
<td class="dsR306 dsR182" content="content" csheight="647" width="248" height="662" colspan="9" rowspan="5" valign="top" xpos="25"><a href="UKPages/UKSonicMerchandise.html">England Sonic the Hedgehog</a><br>
<font size="-1"><a href="UKPages/UKSonicMerchandise2.html">England Sonic the Hedgehog Page 2<br>
</a></font><a href="UKPages/UKSonicMerchandise3.html"><font size="-1">England Sonic the Hedgehog Page 3<br>
</font></a><a href="UKPages/UKSonicMerchandise4.html"><font size="-1">England Sonic the Hedgehog Page 4</font><br>
</a><font size="-2"><a href="UKPages/UKSonicMerchandise5.html">England Sonic the Hedgehog Page 5<br>
</a><a href="UKPages/UKSonicMerchandise6.html">England Sonic the Hedgehog Page 6<br>
</a></font><font size="-1"><a href="UKPages/UKBooks.html">England Sonic the Hedgehog Books</a><br>
<a href="UKPages/UKBooks2.html">England Sonic the Hedgehog Books 2</a><br>
<a href="UKPages/ClassicUKClothes.html">England Sonic Classic Clothing</a><br>
<a href="UKPages/ClassicUKClothes2.html">UK Classic Clothing 2<br>
</a><a href="UKPages/UKSonicClothes3.html">UK Classic Clothing 3<br>
</a><a href="UKPages/ClassicUKClothes4.html">UK Classic Clothing 4<br>
</a><a href="UKPages/NewUKclothes.html">England Sonic Current Clothing<br>
</a><a href="UKPages/NewUKclothes2.html">England Current Clothing 2<br>
</a><a href="UKPages/NewUKClothes3.html">England Current Clothing 3</a><br>
<a href="UKPages/NewUKClothes4.html">England Current Clothing 4<br>
</a><a href="UKPages/NewUKClothes5.html">England Current Clothing 5<br>
</a><a href="UKPages/NewUKClothes6.html">England Current Clothing 6<br>
</a><a href="UKPages/NewUKClothes7.html">England Current Clothing 7<br>
</a><a href="UKPages/UKHousehold.html">England Sonic Household Goods<br>
</a><a href="UKPages/UKHousehold2.html">England Sonic Household Goods 2<br>
</a><a href="UKPages/UKHousehold3.html">England Sonic Household Goods 3<br>
</a><a href="UKPages/UKHousehold4.html">England Sonic Household Goods 4<br>
</a><a href="UKPages/UKHousehold5.html">England Sonic Household Goods 5<br>
</a><a href="UKPages/UKSonicFoods.html">England Sonic the Hedgehog Food<br>
</a><a href="UKPages/UKAccessories.html">England Sonic the Hedgehog Accessories<br>
</a><a href="UKPages/UKAccessories2.html">England Sonic Accessories 2<br>
</a><a href="UKPages/UKAccessories3.html">England Sonic Accessories 3<br>
</a><a href="UKPages/UKKeyChains.html">England Sonic the Hedgehog Keychains<br>
</a><a href="UKPages/UKSonicPlush.html">England Sonic the Hedgehog Plushes<br>
</a><a href="UKPages/UKSonicPlush2.html">England Sonic the Hedgehog Plushes 2<br>
</a><a href="UKPages/UKSonicSchool.html">England Sonic the Hedgehog School Supplies<br>
</a><a href="UKPages/UKSonicSchool2.html">England Sonic School Supplies 2<br>
</a><a href="UKPages/UKUnderwearSonic.html">England Sonic Underwear<br>
</a><a href="UKPages/UKUnderwearSonic2.html">England Sonic Underwear2<br>
</a><a href="UKPages/SleepwearUK.html">England Sonic SleepWear<br>
</a><a href="UKPages/UKElectronics.html">England Sonic Electronics 1<br>
</a><a href="UKPages/UKElectronics2.html">England Sonic Electronics 2<br>
</a><a href="UKPages/UKElectronics3.html">England Sonic Electronics 3<br>
</a><a href="UKPages/DropDeadLine16.html">Drop Dead Sonic Clothing Accessories 1<br>
</a><a href="UKPages/DropDeadLine16B.html">Drop Dead Sonic Clothing Accessories 2</a></font></td>
<td width="146" height="311" colspan="14"></td>
<td width="1" height="311"><spacer type="block" width="1" height="311"></td>
</tr>
<tr height="23">
<td width="241" height="23" colspan="18"></td>
<td class="dsR300 dsR168" content="content" csheight="192" width="272" height="222" colspan="14" rowspan="2" valign="top" xpos="514"><a href="MutantGear/MutantGear.html">Mutant Gear Page</a> , <a href="MutantGear/MutantSonicGear2.html">Mutant Gear 2</a><a href="MutantGear/MutantGear.html"><br>
</a><a href="MutantGear/MutantSonicGear3.html">Mutant Gear 3</a> , <a href="MutantGear/MutantSonicGear4.html">Mutant Gear 4</a><br>
& <a href="MutantGear/MutantSonicGear5.html">Mutant Gear 5</a> <a href="MutantGear/MutantSonicGear6.html">Mutant Gear 6</a><a href="MutantGear/MutantSonicGear7.html"> Mutant Gear 7</a> These Pages Showcase the WORST Sonic items.<br>
<a href="MutantGear/Calander/CalanderOfCrud.html">Calendar of Crud</a>- Holiday horror plush<br>
<a href="MutantGear/Calander/CrockOfChristmas.html">Crock of Christmas</a> -It's not nice quality<br>
<a href="MutantGear/Calander/ValentinesMutants.html">Valentines Poorly Plush</a> - No love here<br>
<a href="ParodyItems/SonicParody.html">Parody Sonic Items</a> - It's not Sonic</td>
<td width="8" height="335" rowspan="3"></td>
<td width="1" height="23"><spacer type="block" width="1" height="23"></td>
</tr>
<tr height="199">
<td width="145" height="312" colspan="13" rowspan="2"></td>
<td width="96" height="199" colspan="5" valign="top" align="left" xpos="418"><img class="dsR297 dsR167" src="Headers-Buttons/MutantGear.jpg" alt="Mutant Gear" height="85" width="87" border="0"></td>
<td width="1" height="199"><spacer type="block" width="1" height="199"></td>
</tr>
<tr height="113">
<td width="144" height="113" colspan="6" valign="top" align="left" xpos="418"><img class="dsR291 dsR169" src="Headers-Buttons/SuperSGear.jpg" alt="Super Sonic Gear" height="95" width="126" border="0"></td>
<td class="dsR294 dsR170" content="content" csheight="96" width="224" height="113" colspan="13" valign="top" xpos="562"><a href="SuperGear/SuperSonicGear.html">Super Sonic Gear</a><br>
This page showcases only the most awesome Sonic items</td>
<td width="1" height="113"><spacer type="block" width="1" height="113"></td>
</tr>
<tr height="16">
<td width="143" height="16" colspan="11"></td>
<td width="368" height="64" colspan="19" rowspan="2" valign="top" align="left" xpos="416"><img class="dsR326 dsR159" src="Headers-Buttons/FEPTop.jpg" alt="Sonic the hedgehog Fan events & Places" height="45" width="355" usemap="#FEPTop6cc591d" border="0"></td>
<td width="10" height="64" colspan="3" rowspan="2"></td>
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<tr height="48">
<td width="304" height="48" colspan="15" valign="top" align="left" xpos="0"><img src="BoomSonic/BoomLogoGearHeader.jpg" alt="" height="44" width="294" border="0"></td>
<td width="112" height="48" colspan="10"></td>
<td width="1" height="48"><spacer type="block" width="1" height="48"></td>
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<tr height="269">
<td width="48" height="294" colspan="8" rowspan="2"></td>
<td content csheight="289" width="258" height="294" colspan="8" rowspan="2" valign="top" xpos="48"><a href="BoomSonic/Prototypes/PrototypesB1.html">Prototypes<br>
</a><a href="BoomSonic/PlushDolls/PlushBoom1.html">Plush Dolls<br>
</a><a href="BoomSonic/ActionFigures/FiguresBoom1.html">Action Figures<br>
</a><a href="BoomSonic/ActionFigures/FiguresBoom2.html">Action Figures 2<br>
</a><a href="BoomSonic/ActionFigures/FiguresBoom3.html">Action Figures 3</a><br>
<a href="BoomSonic/ActionFigures/FiguresBoom4.html">Action Figures 4</a><br>
<a href="BoomSonic/StoreDisplay/StoreDisplayB.html">Retail Display Items<br>
</a><a href="BoomSonic/MiscBoom/RandomItems.html">Random / Misc Items<br>
</a><a href="BoomSonic/MiscBoom/RandomItems2.html">Boom Random 2</a><a href="BoomSonic/MiscBoom/RandomItems.html"><br>
</a><a href="BoomSonic/SchoolBoom/SchoolSupplyBoom1.html">Sonic Boom School Supplies<br>
</a><a href="StoreSonic/BoomPartyStore.html">Sonic Boom Party Store<br>
</a><a href="BoomSonic/ClothingBoom/BoomClothes.html">Sonic Boom Clothing 1</a><br>
<a href="BoomSonic/ClothingBoom/BoomClothes2.html">SonicBoom Clothing 2</a></td>
<td width="126" height="269" colspan="13"></td>
<td class="dsR334 dsR197" content="content" csheight="257" width="226" height="269" colspan="6" valign="top" xpos="432">Sonic In The USA<br>
Sonic <a href="FanEvents/USAEvents/USASonicCostumes.html">Costume Characters</a><br>
<a href="FanEvents/EventsUSA.html">Fan Places & Events</a>
<p>Sonic in Japan<br>
<a href="FanEvents/Japan%20Events/CostumeCharacters.html">Sonic Costume Character</a><a href="FanEvents/Japan%20Events/CostumeCharacters.html">s<br>
</a><span class="ds2"><a href="FanEvents/Japan%20Events/CostumeCharacters2.html">Costume Characters 2<br>
</a></span><a href="FanEvents/Japan%20Events/CostumeCharacters3.html"><span class="ds2">Costume Characters 3</span><br>
</a><a href="FanEvents/Japan%20Events/JapanSonicPlaces.html">Fan Places & Events<br>
</a><font size="-1"><a href="FanEvents/Japan%20Events/JapanSonicPlaces2.html">Fan Places & Events 2</a></font></p>
<p>International Sonic Areas<br>
<a href="FanEvents/WorldPlaces/SonicWorldPlaces.html">World Sonic Places<br>
</a><a href="FanEvents/WorldEvents/SonicWorldEvents.html">World Sonic Events</a></p>
</td>
<td width="136" height="269" colspan="12"></td>
<td width="1" height="269"><spacer type="block" width="1" height="269"></td>
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<tr height="25">
<td width="111" height="25" colspan="10"></td>
<td class="dsR281 dsR175" content="content" csheight="51" width="352" height="60" colspan="17" rowspan="2" valign="top" xpos="417"><a href="MiscItems/WantedGear.html">Wanted Sonic Gear</a>- Things not yet on the site<br>
<a href="CollectionCare/CollectionCare1.html">Collection Care</a> - Keep your Sonic items in top shape!</td>
<td width="25" height="60" colspan="4" rowspan="2"></td>
<td width="1" height="25"><spacer type="block" width="1" height="25"></td>
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<tr height="35">
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<td width="368" height="48" colspan="16" rowspan="2" valign="top" align="left" xpos="17"><img class="dsR286 dsR174" src="Headers-Buttons/VideosTop.jpg" alt="" height="44" width="350" border="0"></td>
<td width="32" height="35" colspan="6"></td>
<td width="1" height="35"><spacer type="block" width="1" height="35"></td>
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<tr height="13">
<td width="48" height="13" colspan="10"></td>
<td width="352" height="53" colspan="15" rowspan="2" valign="top" align="left" xpos="433"><img class="dsR304 dsR171" src="Headers-Buttons/MyTop.jpg" alt="My Sonic the Hedgehog Items" height="44" width="352" usemap="#MyTop76826ea" border="0"></td>
<td width="9" height="53" colspan="2" rowspan="2"></td>
<td width="1" height="13"><spacer type="block" width="1" height="13"></td>
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<tr height="40">
<td width="54" height="217" colspan="9" rowspan="2"></td>
<td class="dsR280 dsR176" content="content" csheight="167" width="250" height="217" colspan="6" rowspan="2" valign="top" xpos="54"><a href="ShowPages/SonicVideoPage.html">Sonic Video Collection: Show Clips<br>
</a><a href="ShowPages/VideoEntertainment.html">Sonic Entertainment Videos</a><a href="ShowPages/SonicVideoPage.html"><br>
</a><a href="ShowPages/CommercialVideos.html">Sonic Commercials from Japan</a><br>
<font size="-1"><a href="ShowPages/CommercialVideos2JP.html">Sonic Commercials Japan 2</a></font><br>
<font size="-1"><a href="ShowPages/CommercialVideos3JP.html">Sonic Commercials Japan 3</a></font><br>
<a href="ShowPages/CommercialVideosUSA.html">Sonic Commercials from America<br>
</a><font size="-1"><a href="ShowPages/CommercialVideosUSA2.html">Sonic Commercials America 2<br>
</a></font><a href="ShowPages/InternationalCommercials.html">International Sonic Commercial Videos</a></td>
<td width="129" height="40" colspan="15"></td>
<td width="1" height="40"><spacer type="block" width="1" height="40"></td>
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<tr height="177">
<td width="162" height="177" colspan="16"></td>
<td class="dsR302 dsR173" content="content" csheight="144" width="256" height="177" colspan="8" valign="top" xpos="466"><a href="MyCollection/FancyBags.html">Fancy Sonic Bags</a><br>
<a href="MyCollection/MyChaoGarden.html">Chao Garden Sculpture Photos</a><br>
<a href="MyCollection/HygeneSonic.html">Sonic the Hedgehog Hygene</a><br>
<a href="MyCollection/MyClothingClassic.html">My Classic Sonic the Hedgehog Clothes</a><br>
<a href="MyCollection/MyClothingCurrent.html">My Current Sonic the Hedgehog Clothes</a><br>
<a href="MyCollection/MyLCDGames.html">My Sonic the Hedgehog LCD Games</a><br>
<a href="MyCollection/MyRandomItems.html">My Random Collected Sonic Items</a></td>
<td width="72" height="177" colspan="8"></td>
<td width="1" height="177"><spacer type="block" width="1" height="177"></td>
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<tr height="114">
<td width="1" height="114"></td>
<td class="dsR283 dsR178" content="content" csheight="97" width="784" height="114" colspan="44" valign="top" xpos="1">Disclaimer: Not all of the photos that appear here are mine. Some of them are quite old. Did you take a photo of something that appears here? Want credit? Just Write Me and you will be credited. You can also write in to supply info on an item if you own it. These photos should NOT be used to sell your own items over Ebay or anywhere else. You can save them if you want, though. That is a good idea. If a photo is yours and you need it taken down Email me and it will be removed. Want your photos here? Send 'em in! AzureBlaze@ msn.com</td>
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Sonic Gear Ultimate Photo Gallery of Sonic the Hedgehog Items
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| | Welcome to Sonic Gear! If it's Sonic the Hedgehog, It's Here! | Sonic The Hedgehog Merchandise Showcase Header | | |
| Welcome to Sonic Gear! If it's Sonic the Hedgehog, It's Here!
The Ultimate Collection...This is the one place on the web where you can find the LARGEST collection of Sonic The Hedgehog goods imaginable! The goal of this site is to show Sonic Fans everywhere images of EVERY Sonic item that was and is available.
There's everything from your regular Sonic Clothing Collection to the unusual and fascinating Sonic Hygene Section! This isn't an ordinary gallery, it provides detailed descriptions, locations and (where applicable) where you can get the item for yourself! Let's go! | | |
| | Sonic the Hedgehog goods Headline News | | |
| |
This just in!
JAKKS PACIFIC figures are in TARGET AND WALMART NOW, as well as 5 Below (sometimes) 06.19.23
GOOD NEWS: GE Entertainment Has Gotten Back the Sonic license in 2019! Older items can be seen at: [GE Sonic Plushes](StoreSonic/PlushStore.html)
BEWARE of FAKE SONIC AMIIBO figures - ONLY Sonic is official - any other Sonic character is NOT a real Amiibo = don't buy it.
FAKE FANG warning. Fake Fang/Knack plushes are all over ebay. See the [Bootleg Guide](BootlegFakes/AvoidBootlegs2.html) on how to avoid him before you bid!
SonicGear appears in an article on Sonic Merchandise! Be sure to read it at [The Sonic Stadium](http://www.sonicstadium.org/features/a-guide-to-sonic-merchandise-part-3-gear-from-across-the-globe).
| | |
| | Read the first reports of Sonic Merchandise | | |
| | [Read More News](NewsPage.html) | | |
| [The Site Blog \*Updated 11.15.23](http://sonicintent.blogspot.com) | | |
| | Looking for a spacific character or item? This site is searchable! | | |
| | Type their name or the product you want to see, into the box. The special tool will pull up just what you want to see from THIS site only. It should work best 1 item or name at a time. Example: Shadow, Tails, Pogs, Pasta, Shampoo, Lamp, Rouge, Mutant. Try odd words, or other things you are interested in--you'll be surprised at what might come out. | | |
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| [Google](http://www.google.com/) | |
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| Web | www.sonicgear.org |
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Announcements & The Latest Updates
Last Update of the Year 12.26.23
It's the last update of 2023, so take a look into the next year early with [New Badnick Figure](USAPages/USAFigures/JakksPacificFigures/5InchFigures/JakksPacific5InchFigures5.html), then see a cool [Mall Display](FanEvents/Japan%20Events/JapanSonicPlaces5.html), some [Amy Energy Powder](USAPages/USAFoods/USAFoods4.html), more [Christmas Ornaments on the NEW Christmas Page](ChristmasHoliday/HolidayChristmas.html), a closer look at the [Cable Guys Shadow](USAPages/USAElectronics/SonicElectronics11.html) & a [Japan Only Display Figure](DisplayFigures/DisplayFigures13.html).
Xmas Update 12.12.23
This update brings a timely new page: [Sonic Christmas Gear](ChristmasHoliday/HolidayChristmas.html). There are also things to add to your list such as [Super Silver Figure](USAPages/USAFigures/JakksPacificFigures/5InchFigures/JakksPacific5InchFigures5.html), a [Strange Duck](USAPages/SonicUSARandom5.html), three new Sonic [Prime Figures](SonicPrime/SonicPrimeItems1.html), and a [First4Figures Statue](MovieSonic/MovieMerchandise5.html). There's also a [Mall Display Super Stars](FanEvents/WorldEvents/SonicWorldEvents2.html) to see while you shop.
Extra Update 12.07.23
Trying to make up for missed updates. There is a [Stickerbomb Plush](USAPages/USAPlushes/SonicPlushesUSA20.html), a look at [Buildable Knuckles](DisplayFigures/DisplayFigures13.html), then [Build a Bear releases an Odd Super Sonic](MovieSonic/MovieMerchandise4.html), there are 3 new [Sonic Electronics Items](USAPages/USAElectronics/SonicElectronics11.html), and a look at NEW (good news) [Jakks Pacific Packaging](USAPages/USAFigures/JakksPacificFigures/5InchFigures/JakksPacific5InchFigures5.html), then an [Ad That's Old & New](USAPages/SonicRetailDisplay3.html), and finally a [Prime Figure closer look](SonicPrime/SonicPrimeItems1.html).
Not Enough of the Update 12.05.23
Just a normal update (yea normally late ugh) but it still has 6 things and some ok variety because [France Ceramic Items](FrancePages/FrancePage3.html) & [Brazil Superstars Pin](BrazilPages/BrazilItems2.html). There's also some [Box Lunch Winter Wear](USAPages/WinterWear/SonicWinterWear13.html), 2 [Box Lunch Jerseies](USAPages/USAClothesRecent5/USAClothesRecent42.html), & [King Ice](USAPages/JewelrySonic.html) is really glamming it up this week as well. But what's an [Adventure Toothbrush](USAPages/USAHygene/SonicHygene3.html)? (answer isnt here)
Return of the Update 11.15.23
As expected, the last one skipped but the update is back, and with more stuff. There's a [France Fleece](FrancePages/FrancePage3.html), a better look at [Chopper Fish](USAPages/USAFigures/JakksPacificFigures/SmallLineFigures/JakksPacificSmallLineFigures5.html) & [New Gold Series Figure](USAPages/USAFigures/JakksPacificFigures/5InchFigures/JakksPacific5InchFigures5.html), and a new [Lay Down Plush](USAPages/USAPlushes/SonicPlushesUSA20.html). Then see a [Sonic Fridge](USAPages/USAHomeDecor/USAHomeDeco2/HomeDecorUSA21.html)? (Its real!), [2 Sweat Shirts](USAPages/WinterWear/SonicWinterWear12.html) for the season, a [Box Lunch Shirt](USAPages/USAClothesRecent5/USAClothesRecent42.html), & some [Guitar Picks](JapanPages/JapanSonicRandom4.html) too.
Early Update 10.26.23
This update is early because the next one will be skipped. There are [3 new Bed Items](UKPages/UK%20Photos/UKHomeDecor/UKHousehold6.html) to see in the UK area, then a [New Box For Chao](USAPages/USAFigures/JakksPacificFigures/SmallLineFigures/JakksPacificSmallLineFigures5.html), celebrate Superstars with a [Famitsu Cover](MiscItems/SonicMagazines8.html), then see [Just Funky's Pinboard](USAPages/USKeychainsPins/SonicPinsKeychains8.html), an [Ice Cream Theme Tee](USAPages/USAClothesRecent5/USAClothesRecent42.html) & 2 new [Hallmark Sonic Ornaments](USAPages/SonicUSARandom6.html).
2 Of Most Things Update 10.22.23
This update is bigger than usual too so there's more to enjoy like [2 Glitter Pins](USAPages/USKeychainsPins/SonicPinsKeychains8.html), first look at [Just Funky Plush](USAPages/USAPlushes/SonicPlushesUSA20.html), a [Coin Bank](USAPages/USAHomeDecor/USAHomeDeco2/HomeDecorUSA20.html), and then [2 Party Supplies](USAPages/PartySupplies/SonicPartySupplies5.html),
[ASRock PC Motherboard & a random Phone Stand](USAPages/USAElectronics/SonicElectronics11.html), plus the [Fuji Q Highland Sonic Place](FanEvents/Japan%20Events/JapanSonicPlaces5.html). Then there's a [Celebration Cake](UKPages/UK%20Photos/UKFoods/UKSonicFoods2.html) & [2 Sakura Tees](USAPages/USAClothesRecent5/USAClothesRecent42.html).
On Time 8 Item Update 10.17.23
The focus here is mostly on new stuff so see a new company [Mighty Mojo Pool Float](USAPages/SwimGear/SwimGearSonic1.html) AND [Party Supplies Sonic](USAPages/PartySupplies/SonicPartySupplies5.html). Then there's the [Halloween Costume Pirate Pin](USAPages/USKeychainsPins/SonicPinsKeychains8.html), a look at [Pix n' Love Origins Bonus](UKPages/UKElectronics3.html), the final of [Flying Heroes Toy](USAPages/SonicUSARandom6.html), some [Funky Pillow Faces](USAPages/USAHomeDecor/USAHomeDeco2/HomeDecorUSA20.html), old [Zega Zone Australia Items](AustraliaPages/AustraliaItems9.html) & [Power A Controller](USAPages/USAElectronics/SonicElectronics11.html).
A Bit Late & More Stuff Update 10.09.23
As is tradition in October, there's a [Halloween Costume](USAPages/HalloweenUSA/HalloweenUSA2.html) to see first, then some [NYCC Pins](USAPages/USKeychainsPins/SonicPinsKeychains8.html), and a [New Funko Soda](DisplayFigures/DisplayFigures13.html). Then see what [AI Art might do](BootlegFakes/AvoidingBootlegs37.html), GE's New [Amy Dol](USAPages/USAPlushes/SonicPlushesUSA20.html)l, a better look at [Boxed Infinite Jackal](USAPages/USAFigures/JakksPacificFigures/5InchFigures/JakksPacific5InchFigures5.html), NKOK re-releases the [Tails All Star Racer](USAPages/NKOKSonicFigures.html) and finally a [Cool New Tee](USAPages/USAClothesRecent5/USAClothesRecent42.html).
[Don't Use Ad Block on SonicGear](TextPages/WhyNoAdblock.html) mini-article also gets an update with pictures to help explain it.
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| | Sonic the Hedgehog around the world | | |
| | [Australia Sonic the Hedgehog](AustraliaPages/AustraliaItems.html)[Australia Sonic Page 2](AustraliaPages/AustraliaItems2.html)[Australia Sonic Page 3](AustraliaPages/AustraliaItems3.html)
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[Saudi Arabia Sonic the Hedgehog](SaudiArabiaPage/SArabiaPage.html)
[Spain Sonic The Hedgehog](SpainPages/SpainPage.html)[Unknown International Sonic Items](InternationalUnknown.html) | | |
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[England Current Clothing 4](UKPages/NewUKClothes4.html)[England Current Clothing 5](UKPages/NewUKClothes5.html)[England Current Clothing 6](UKPages/NewUKClothes6.html)[England Current Clothing 7](UKPages/NewUKClothes7.html)[England Sonic Household Goods](UKPages/UKHousehold.html)[England Sonic Household Goods 2](UKPages/UKHousehold2.html)[England Sonic Household Goods 3](UKPages/UKHousehold3.html)[England Sonic Household Goods 4](UKPages/UKHousehold4.html)[England Sonic Household Goods 5](UKPages/UKHousehold5.html)[England Sonic the Hedgehog Food](UKPages/UKSonicFoods.html)[England Sonic the Hedgehog Accessories](UKPages/UKAccessories.html)[England Sonic Accessories 2](UKPages/UKAccessories2.html)[England Sonic Accessories 3](UKPages/UKAccessories3.html)[England Sonic the Hedgehog Keychains](UKPages/UKKeyChains.html)[England Sonic the Hedgehog Plushes](UKPages/UKSonicPlush.html)[England Sonic the Hedgehog Plushes 2](UKPages/UKSonicPlush2.html)[England Sonic the Hedgehog School Supplies](UKPages/UKSonicSchool.html)[England Sonic School Supplies 2](UKPages/UKSonicSchool2.html)[England Sonic Underwear](UKPages/UKUnderwearSonic.html)[England Sonic Underwear2](UKPages/UKUnderwearSonic2.html)[England Sonic SleepWear](UKPages/SleepwearUK.html)[England Sonic Electronics 1](UKPages/UKElectronics.html)[England Sonic Electronics 2](UKPages/UKElectronics2.html)[England Sonic Electronics 3](UKPages/UKElectronics3.html)[Drop Dead Sonic Clothing Accessories 1](UKPages/DropDeadLine16.html)[Drop Dead Sonic Clothing Accessories 2](UKPages/DropDeadLine16B.html) | | |
| | [Mutant Gear Page](MutantGear/MutantGear.html) , [Mutant Gear 2](MutantGear/MutantSonicGear2.html)[Mutant Gear 3](MutantGear/MutantSonicGear3.html) , [Mutant Gear 4](MutantGear/MutantSonicGear4.html)
& [Mutant Gear 5](MutantGear/MutantSonicGear5.html) [Mutant Gear 6](MutantGear/MutantSonicGear6.html) [Mutant Gear 7](MutantGear/MutantSonicGear7.html) These Pages Showcase the WORST Sonic items.
[Calendar of Crud](MutantGear/Calander/CalanderOfCrud.html)- Holiday horror plush
[Crock of Christmas](MutantGear/Calander/CrockOfChristmas.html) -It's not nice quality
[Valentines Poorly Plush](MutantGear/Calander/ValentinesMutants.html) - No love here
[Parody Sonic Items](ParodyItems/SonicParody.html) - It's not Sonic | | |
| | Mutant Gear | |
| Super Sonic Gear | [Super Sonic Gear](SuperGear/SuperSonicGear.html)
This page showcases only the most awesome Sonic items | |
| | Sonic the hedgehog Fan events & Places | | |
| | | |
| | [Prototypes](BoomSonic/Prototypes/PrototypesB1.html)[Plush Dolls](BoomSonic/PlushDolls/PlushBoom1.html)[Action Figures](BoomSonic/ActionFigures/FiguresBoom1.html)[Action Figures 2](BoomSonic/ActionFigures/FiguresBoom2.html)[Action Figures 3](BoomSonic/ActionFigures/FiguresBoom3.html)
[Action Figures 4](BoomSonic/ActionFigures/FiguresBoom4.html)
[Retail Display Items](BoomSonic/StoreDisplay/StoreDisplayB.html)[Random / Misc Items](BoomSonic/MiscBoom/RandomItems.html)[Boom Random 2](BoomSonic/MiscBoom/RandomItems2.html)[Sonic Boom School Supplies](BoomSonic/SchoolBoom/SchoolSupplyBoom1.html)[Sonic Boom Party Store](StoreSonic/BoomPartyStore.html)[Sonic Boom Clothing 1](BoomSonic/ClothingBoom/BoomClothes.html)
[SonicBoom Clothing 2](BoomSonic/ClothingBoom/BoomClothes2.html) | | Sonic In The USA
Sonic [Costume Characters](FanEvents/USAEvents/USASonicCostumes.html)
[Fan Places & Events](FanEvents/EventsUSA.html)
Sonic in Japan
[Sonic Costume Character](FanEvents/Japan%20Events/CostumeCharacters.html)[s](FanEvents/Japan%20Events/CostumeCharacters.html)[Costume Characters 2](FanEvents/Japan%20Events/CostumeCharacters2.html)[Costume Characters 3](FanEvents/Japan%20Events/CostumeCharacters3.html)[Fan Places & Events](FanEvents/Japan%20Events/JapanSonicPlaces.html)[Fan Places & Events 2](FanEvents/Japan%20Events/JapanSonicPlaces2.html)
International Sonic Areas
[World Sonic Places](FanEvents/WorldPlaces/SonicWorldPlaces.html)[World Sonic Events](FanEvents/WorldEvents/SonicWorldEvents.html) | | |
| | [Wanted Sonic Gear](MiscItems/WantedGear.html)- Things not yet on the site
[Collection Care](CollectionCare/CollectionCare1.html) - Keep your Sonic items in top shape! | | |
| | | | |
| | My Sonic the Hedgehog Items | | |
| | [Sonic Video Collection: Show Clips](ShowPages/SonicVideoPage.html)[Sonic Entertainment Videos](ShowPages/VideoEntertainment.html)[Sonic Commercials from Japan](ShowPages/CommercialVideos.html)
[Sonic Commercials Japan 2](ShowPages/CommercialVideos2JP.html)
[Sonic Commercials Japan 3](ShowPages/CommercialVideos3JP.html)
[Sonic Commercials from America](ShowPages/CommercialVideosUSA.html)[Sonic Commercials America 2](ShowPages/CommercialVideosUSA2.html)[International Sonic Commercial Videos](ShowPages/InternationalCommercials.html) | | |
| | [Fancy Sonic Bags](MyCollection/FancyBags.html)
[Chao Garden Sculpture Photos](MyCollection/MyChaoGarden.html)
[Sonic the Hedgehog Hygene](MyCollection/HygeneSonic.html)
[My Classic Sonic the Hedgehog Clothes](MyCollection/MyClothingClassic.html)
[My Current Sonic the Hedgehog Clothes](MyCollection/MyClothingCurrent.html)
[My Sonic the Hedgehog LCD Games](MyCollection/MyLCDGames.html)
[My Random Collected Sonic Items](MyCollection/MyRandomItems.html) | | |
| | Disclaimer: Not all of the photos that appear here are mine. Some of them are quite old. Did you take a photo of something that appears here? Want credit? Just Write Me and you will be credited. You can also write in to supply info on an item if you own it. These photos should NOT be used to sell your own items over Ebay or anywhere else. You can save them if you want, though. That is a good idea. If a photo is yours and you need it taken down Email me and it will be removed. Want your photos here? Send 'em in! AzureBlaze@ msn.com | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| http://www.sonicgear.org/ |
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<html xmlns="http://www.w3.org/1999/xhtml"><head><title>The Jargon File</title><link rel="stylesheet" href="jargon.css" type="text/css"/><meta name="generator" content="DocBook XSL Stylesheets V1.61.0"/><link rel="home" href="index.html" title="The Jargon File"/><link rel="next" href="online-preface.html" title="Welcome to the Jargon File"/></head><body><div class="navheader"><table width="100%" summary="Navigation header"><tr><th colspan="3" align="center">The Jargon File</th></tr><tr><td width="20%" align="left"> </td><th width="60%" align="center"> </th><td width="20%" align="right"> <a accesskey="n" href="online-preface.html">Next</a></td></tr></table><hr/></div><div class="book" lang="en"><div class="titlepage"><div><div><h1 class="title"><a id="id2890003"/>The Jargon File</h1></div><div><h2 class="subtitle">(version 4.4.7)</h2></div></div><div/><hr/></div><div class="toc"><p><b>Table of Contents</b></p><dl><dt><a href="online-preface.html">Welcome to the Jargon File</a></dt><dt>I. <a href="pt01.html">Introduction</a></dt><dd><dl><dt>1. <a href="introduction.html">Hacker Slang and Hacker Culture</a></dt><dt>2. <a href="distinctions.html">Of Slang, Jargon, and Techspeak</a></dt><dt>3. <a href="revision-history.html">Revision History</a></dt><dt>4. <a href="construction.html">Jargon Construction</a></dt><dd><dl><dt><a href="verb-doubling.html">Verb Doubling</a></dt><dt><a href="soundalike-slang.html">Soundalike Slang</a></dt><dt><a href="p-convention.html">The -P Convention</a></dt><dt><a href="overgeneralization.html">Overgeneralization</a></dt><dt><a href="inarticulations.html">Spoken inarticulations</a></dt><dt><a href="anthropomorphization.html">Anthropomorphization</a></dt><dt><a href="comparatives.html">Comparatives</a></dt></dl></dd><dt>5. <a href="writing-style.html">Hacker Writing Style</a></dt><dt>6. <a href="email-style.html">Email Quotes and Inclusion Conventions</a></dt><dt>7. <a href="speech-style.html">Hacker Speech Style</a></dt><dt>8. <a href="international-style.html">International Style</a></dt><dt>9. <a href="crackers.html">Crackers, Phreaks, and Lamers</a></dt><dt>10. <a href="pronunciation.html">Pronunciation Guide</a></dt><dt>11. <a href="conventions.html">Other Lexicon Conventions</a></dt><dt>12. <a href="submitting-new-entries.html">Format for New Entries</a></dt></dl></dd><dt>II. <a href="lexicon.html">The Jargon Lexicon</a></dt><dd><dl><dt xmlns=""><a href="go01.html">Glossary</a></dt></dl></dd><dt>III. <a href="pt03.html">Appendices</a></dt><dd><dl><dt>A. <a href="appendixa.html">Hacker Folklore</a></dt><dd><dl><dt><a href="meaning-of-hack.html">The Meaning of ‘Hack’</a></dt><dt><a href="tv-typewriters.html">TV Typewriters: A Tale of Hackish Ingenuity</a></dt><dt><a href="magic-story.html">A Story About ‘Magic'</a></dt><dt><a href="koans.html">Some AI Koans</a></dt><dd><dl><dt><a href="koans.html#id3141171">Tom Knight and the Lisp Machine</a></dt><dt><a href="koans.html#id3141202">Moon instructs a student</a></dt><dt><a href="koans.html#id3141241">Sussman attains enlightenment</a></dt><dt><a href="koans.html#id3141308">Drescher and the toaster</a></dt></dl></dd><dt><a href="os-and-jedgar.html">OS and JEDGAR</a></dt><dt><a href="story-of-mel.html">The Story of Mel</a></dt></dl></dd><dt>B. <a href="appendixb.html">A Portrait of J. Random Hacker</a></dt><dd><dl><dt><a href="appearance.html">General Appearance</a></dt><dt><a href="dress.html">Dress</a></dt><dt><a href="reading_habits.html">Reading Habits</a></dt><dt><a href="other-interests.html">Other Interests</a></dt><dt><a href="physical.html">Physical Activity and Sports</a></dt><dt><a href="education.html">Education</a></dt><dt><a href="hates.html">Things Hackers Detest and Avoid</a></dt><dt><a href="food.html">Food</a></dt><dt><a href="politics.html">Politics</a></dt><dt><a href="demographics.html">Gender and Ethnicity</a></dt><dt><a href="religion.html">Religion</a></dt><dt><a href="chemicals.html">Ceremonial Chemicals</a></dt><dt><a href="communication_style.html">Communication Style</a></dt><dt><a href="geography.html">Geographical Distribution</a></dt><dt><a href="sex.html">Sexual Habits</a></dt><dt><a href="personality.html">Personality Characteristics</a></dt><dt><a href="weaknesses.html">Weaknesses of the Hacker Personality</a></dt><dt><a href="miscellaneous.html">Miscellaneous</a></dt></dl></dd><dt>C. <a href="appendixc.html">Helping Hacker Culture Grow</a></dt><dt><a href="pt03.html#bibliography">Bibliography</a></dt></dl></dd></dl></div></div><div class="navfooter"><hr/><table width="100%" summary="Navigation footer"><tr><td width="40%" align="left"> </td><td width="20%" align="center"> </td><td width="40%" align="right"> <a accesskey="n" href="online-preface.html">Next</a></td></tr><tr><td width="40%" align="left" valign="top"> </td><td width="20%" align="center"> </td><td width="40%" align="right" valign="top"> Welcome to the Jargon File</td></tr></table></div></body></html>
| xml version="1.0" encoding="UTF-8" standalone="no"?
The Jargon File
| The Jargon File |
| --- |
| | | [Next](online-preface.html) |
---
# The Jargon File
## (version 4.4.7)
---
**Table of Contents**
[Welcome to the Jargon File](online-preface.html)I. [Introduction](pt01.html)1. [Hacker Slang and Hacker Culture](introduction.html)2. [Of Slang, Jargon, and Techspeak](distinctions.html)3. [Revision History](revision-history.html)4. [Jargon Construction](construction.html)[Verb Doubling](verb-doubling.html)[Soundalike Slang](soundalike-slang.html)[The -P Convention](p-convention.html)[Overgeneralization](overgeneralization.html)[Spoken inarticulations](inarticulations.html)[Anthropomorphization](anthropomorphization.html)[Comparatives](comparatives.html)5. [Hacker Writing Style](writing-style.html)6. [Email Quotes and Inclusion Conventions](email-style.html)7. [Hacker Speech Style](speech-style.html)8. [International Style](international-style.html)9. [Crackers, Phreaks, and Lamers](crackers.html)10. [Pronunciation Guide](pronunciation.html)11. [Other Lexicon Conventions](conventions.html)12. [Format for New Entries](submitting-new-entries.html)II. [The Jargon Lexicon](lexicon.html)[Glossary](go01.html)III. [Appendices](pt03.html)A. [Hacker Folklore](appendixa.html)[The Meaning of ‘Hack’](meaning-of-hack.html)[TV Typewriters: A Tale of Hackish Ingenuity](tv-typewriters.html)[A Story About ‘Magic'](magic-story.html)[Some AI Koans](koans.html)[Tom Knight and the Lisp Machine](koans.html#id3141171)[Moon instructs a student](koans.html#id3141202)[Sussman attains enlightenment](koans.html#id3141241)[Drescher and the toaster](koans.html#id3141308)[OS and JEDGAR](os-and-jedgar.html)[The Story of Mel](story-of-mel.html)B. [A Portrait of J. Random Hacker](appendixb.html)[General Appearance](appearance.html)[Dress](dress.html)[Reading Habits](reading_habits.html)[Other Interests](other-interests.html)[Physical Activity and Sports](physical.html)[Education](education.html)[Things Hackers Detest and Avoid](hates.html)[Food](food.html)[Politics](politics.html)[Gender and Ethnicity](demographics.html)[Religion](religion.html)[Ceremonial Chemicals](chemicals.html)[Communication Style](communication_style.html)[Geographical Distribution](geography.html)[Sexual Habits](sex.html)[Personality Characteristics](personality.html)[Weaknesses of the Hacker Personality](weaknesses.html)[Miscellaneous](miscellaneous.html)C. [Helping Hacker Culture Grow](appendixc.html)[Bibliography](pt03.html#bibliography)
---
| | | |
| --- | --- | --- |
| | | [Next](online-preface.html) |
| | | Welcome to the Jargon File |
| http://catb.org/jargon/html/ |
<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
<HTML>
<HEAD>
<TITLE>www.2112.net</TITLE>
</HEAD>
<META name="description"
content="FREE Rush-related server space. Mostly tabs and lyrics right now. Please contribute your page!">
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<BODY
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VLINK="#B0B0B0"
ALINK="#FF0000"
>
<H1 ALIGN="CENTER">Welcome to www.2112.net!</H1>
<P ALIGN="CENTER">
<BR><BR>Le Menu:<BR>
<BR><A HREF="http://www.2112.net/powerwindows/"><IMG border=0 SRC="pwbanner.gif" ALT="Power Windows"></A>
<BR><A HREF="http://www.2112.net/vertigo/"><IMG border=0 HEIGHT=55 WIDTH=368 SRC="vertibar.jpg" ALT="Video Vertigo"></A>
<BR><A HREF="http://www.2112.net/xanadu/"><IMG border=0 HEIGHT=50 WIDTH=389 SRC="xanadu.gif" ALT="Xanadu Temples"></A>
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</P>
<P ALIGN="CENTER">
If you have a Rush page you would like to host here, please send mail to <FONT COLOR="0000FF">www at 2112 dot net</FONT></A>. If you're interested in Rush guitar tablature, check out the <A HREF="http://www.cygnusproductions.com/rtp/">Rush Tablature Project</A>.<BR><HR></P>
<P ALIGN="CENTER">Rush finally got into the hall of fame, now it's
<A HREF="http://www.rocktheinternet.com/rush/001/index.html">time for a Google doodle!</A><BR>
<P ALIGN="CENTER">2112.net featured on <A HREF="http://unitedrock.com/">United Rock Radio's</A> "Worldwide Web in Rock" program, hosted by Double DJ:</P>
<P ALIGN="CENTER"><A HREF="http://unitedrock.com/"><IMG SRC="www-in-rock.jpg" WIDTH=229 HEIGHT=144 BORDER=0 ALT="Double DJ and United Rock Radio Present: Worldwide Web in Rock"></A><HR></P>
<P ALIGN="CENTER">
<BR>Please read Janis Ian's <A HREF="http://www.janisian.com/article-internet_debacle.html">article</A> and <A HREF="http://www.janisian.com/article-fallout.html">followup</A> on dowloading music and how it affects the entertainment industry, and tell your elected representatives how you feel!</P>
<P ALIGN="CENTER">
If you care about the future of internet radio and you're registered to vote in the US, please take a few mintutes to <A HREF="http://somafm.com/openletter/">learn about the issues at hand</A> and
<A HREF="http://www.house.gov/inslee/issues/technology/internet_radio.html">have a look</A> at where your elected representatives stand.</P>
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www.2112.net
# Welcome to www.2112.net!
Le Menu:
[![Power Windows](pwbanner.gif)](http://www.2112.net/powerwindows/)
[![Video Vertigo](vertibar.jpg)](http://www.2112.net/vertigo/)
[![Xanadu Temples](xanadu.gif)](http://www.2112.net/xanadu/)
[![Bravado](bravadologo.jpg)](http://www.2112.net/bravado/)
[![The Temple of Syrinx](/syrinx/tos.gif)](http://www.2112.net/syrinx/)
[![Rush Artifacts](artibanner.gif)](http://www.2112.net/artifacts/)
[Sphere](http://www.2112.net/sphere/)
[Cygnus X-1](http://www.2112.net/cygnus/)
If you have a Rush page you would like to host here, please send mail to www at 2112 dot net. If you're interested in Rush guitar tablature, check out the [Rush Tablature Project](http://www.cygnusproductions.com/rtp/).
---
Rush finally got into the hall of fame, now it's
[time for a Google doodle!](http://www.rocktheinternet.com/rush/001/index.html)
2112.net featured on [United Rock Radio's](http://unitedrock.com/) "Worldwide Web in Rock" program, hosted by Double DJ:
[![Double DJ and United Rock Radio Present: Worldwide Web in Rock](www-in-rock.jpg)](http://unitedrock.com/)
---
Please read Janis Ian's [article](http://www.janisian.com/article-internet_debacle.html) and [followup](http://www.janisian.com/article-fallout.html) on dowloading music and how it affects the entertainment industry, and tell your elected representatives how you feel!
If you care about the future of internet radio and you're registered to vote in the US, please take a few mintutes to [learn about the issues at hand](http://somafm.com/openletter/) and
[have a look](http://www.house.gov/inslee/issues/technology/internet_radio.html) at where your elected representatives stand.
[![OpenBSD: Functional, Secure, Free. |](portablebsd.gif)](http://www.openbsd.org/)
[![| Powered by Apache](apache_logo.gif)](http://www.apache.org/httpd.html)
| http://www.2112.net/ |
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<link href="lindholm.css" rel="stylesheet" type="text/css" />
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function showmenu(which)
{
if (which != 'home') document.getElementById('home').style.display = 'none';
if (which != 'pictures') document.getElementById('pictures').style.display = 'none';
if (which != 'music') document.getElementById('music').style.display = 'none';
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<a href="http://lukebiewald.com">Lukas A. Biewald</a>
<a href="http://pamolson.org">Pamela J. Olson</a>
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<div class="heading"> Steve’s Page o’ Love </div>
<div class="para">
<div class= "caprnc" ><a href= "pix/clipart/prego_monkey.jpeg" ><img src= "pix/clipart/prego_monkey.jpeg" alt= "Pregnant Monkey" class= "p000" /></a></div>
I last updated my web page three years ago and in that time I’ve moved out of undergraduate housing, finished
my master’s, come back to Stanford to start law school, and started my first real job. Yet returning visitors
need not fear; despite all of my life changes, this web page will still satify your pregnant monkey needs
for years to come.</div>
<div class="para">The Monkey of the Day is: </div>
<div class="para"><object class="monkeyframe"
data="http://lukebiewald.com/cgi-bin/motd.html"></object></div>
<div class="para">I have a real job now; I’m working at a law firm for the summer.
Hopefully, they will let me work there when I graduate. I would give a link, but I fear
that during the intervening three years before I update my web page again, France will
have taken away our domain name. (I’m not kidding, they really are trying to do that.)
Now that I have a real job, I am no longer irritated by people who ask me when I plan to
get one. That particular problem vexed me for years.</div>
<div class="heading">Common Misunderstandings, Redux</div>
<div class="para">
<div class= "capl" ><a href= "pix/formative/IMG_0286_ed.jpg" ><img src= "pix/formative/IMG_0286_ed.jpg" alt="" class= "p320" /></a><p> Me with Pam and the prez </p></div>
Myself, I’m 24 years old. I go to law school at Stanford University. I have finished my
first year, and I have two more to go until I graduate. This means that exactly one
third of my personality has been drained from my soul into a insulated, untippable
coffee mug with “WestLaw” silk-screened onto the side in neat, blue letters. Law school
is, in fact, taking me the same amount of time as my computer science master’s did. It
is, however, much less fun. Grad school is like welfare, but with better food and less
poon-tang. Law school is like Stalin’s gulag, but with more palm trees and pricier
books.</div>
<div class="para">I mentioned before that I’m no longer innundated by questions like
“When are you going to find a real job?” “When are you going to move out of
undergraduate housing?” I have a new irritation: People who wait for parking spaces to
open. It’s a good thing I will never hold political office, because if I had my
druthers, those inconsiderate bastards would be shot. Just this last week, I was in the
Wal*Mart parking lot, behind another car. The driver of this car needed a parking space.
She decided not to take the open space right in front of her, but the one <strong>two
spaces ahead of her</strong> which was, of course, occupied by a car that was pulling
out. By the grace of $diety, I managed to squeeze past her car into the spot she passed
up. By the time I was in the store, she was still parking her car.</div>
<div class="heading">Nakedness</div>
<div class="para">Contrary to rumors, and to what you might infer from my <a
href="chpic_idx.html">pictures page</a>, I do not trade pictures of naked people.
Honestly, I really don’t have that many. It’s simply not something I care about. If you
really want to see people naked, your best bet is to go to an <a
href="http://xox.stanford.edu">event</a> <a
href="http://www.stanford.edu/group/columbae/">where</a> <a
href="http://www.stanford.edu/group/Synergy/">people</a> <a
href="http://www.baytobreakers.com/">are</a> <a
href="http://www.stanford.edu/home/welcome/campus/quad.html">naked</a> and se quita your
own ropa.</div>
<div class="heading">Svenska</div>
<div class="para">Finally, I don’t speak Swedish. Really, I don’t. Many bona fide
Swedish people like to try holding little conversations with me. It just doesn’t work.
Actually, a few months ago I changed my Powerbook language to Swedish, so out of pure
necessity I’ve learned the words for things like “window,” “computer,” “printer,” etc.
But it’s simply not possible to hold a sensible conversion with just those words!</div>
<div class="para">The default paper size on my Powerbook changed to A4 when I changed
the language to Swedish. I finally found a place on Veterans Blvd. in Redwood City that
sells decent quality A4 paper at a reasonable price: XPEDX. They’re in the yellow pages
under “Paper.” Metric envelopes are a bigger challenge. There is a Japanese stationery
store at the Town and Country Shopping Center which sells the cutest stationery, but no
standard metric envelopes.</div>
</div>
</body>
</html>
| xml version="1.0" encoding="ISO-8859-1" ?
function showmenu(which)
{
if (which != 'home') document.getElementById('home').style.display = 'none';
if (which != 'pictures') document.getElementById('pictures').style.display = 'none';
if (which != 'music') document.getElementById('music').style.display = 'none';
if (which != 'projects') document.getElementById('projects').style.display = 'none';
if (which != 'myinfo') document.getElementById('myinfo').style.display = 'none';
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if (which != 'links') document.getElementById('links').style.display = 'none';
document.getElementById(which).style.display = 'block';
return true;
}
Stephen Lindholm - Stanford University
[Home](index.html)
[Pictures](chpic_sco.html)
[Sacred music](chmus_idx.html)
[Projects](chpro_idx.html)
[Information for me](chinf_tip.html)
[Information for you](chinf_tal.html)
[Fellow hippies](#)
[Top page](index.html)
[About this site](chhom_abo.html)
[Scotland](chpic_sco.html)
[Formative Years](chpic_for.html)
[Japan](chpic_jap.html)
[Adolescence](chpic_ado.html)
[Aerial balloon](chpro_bal.html)
[About my projects](chpro_idx.html)
[Balloon pictures](chpro_bal.html)
[Tropical horticulture](chpro_hor.html)
[Animal husbandry](chpro_ani.html)
[Research papers](chpro_res.html)
[Software](chpro_sof.html)
[Super Monkey Ball 2](chinf_smb.html)
[Nerd tips](chinf_tip.html)
[Admit MSCS](chinf_adm.html)
[Buchanan gay?](chinf_buc.html)
[Square watermelon](chinf_wat.html)
[Strom retrospective](chinf_str.html)
[My many talents](chinf_tal.html)
[Lukas A. Biewald](http://lukebiewald.com)
[Pamela J. Olson](http://pamolson.org)
Steve’s Page o’ Love
[![Pregnant Monkey](pix/clipart/prego_monkey.jpeg)](pix/clipart/prego_monkey.jpeg)
I last updated my web page three years ago and in that time I’ve moved out of undergraduate housing, finished
my master’s, come back to Stanford to start law school, and started my first real job. Yet returning visitors
need not fear; despite all of my life changes, this web page will still satify your pregnant monkey needs
for years to come.
The Monkey of the Day is:
I have a real job now; I’m working at a law firm for the summer.
Hopefully, they will let me work there when I graduate. I would give a link, but I fear
that during the intervening three years before I update my web page again, France will
have taken away our domain name. (I’m not kidding, they really are trying to do that.)
Now that I have a real job, I am no longer irritated by people who ask me when I plan to
get one. That particular problem vexed me for years.
Common Misunderstandings, Redux
[![](pix/formative/IMG_0286_ed.jpg)](pix/formative/IMG_0286_ed.jpg) Me with Pam and the prez
Myself, I’m 24 years old. I go to law school at Stanford University. I have finished my
first year, and I have two more to go until I graduate. This means that exactly one
third of my personality has been drained from my soul into a insulated, untippable
coffee mug with “WestLaw” silk-screened onto the side in neat, blue letters. Law school
is, in fact, taking me the same amount of time as my computer science master’s did. It
is, however, much less fun. Grad school is like welfare, but with better food and less
poon-tang. Law school is like Stalin’s gulag, but with more palm trees and pricier
books.
I mentioned before that I’m no longer innundated by questions like
“When are you going to find a real job?” “When are you going to move out of
undergraduate housing?” I have a new irritation: People who wait for parking spaces to
open. It’s a good thing I will never hold political office, because if I had my
druthers, those inconsiderate bastards would be shot. Just this last week, I was in the
Wal\*Mart parking lot, behind another car. The driver of this car needed a parking space.
She decided not to take the open space right in front of her, but the one **two
spaces ahead of her** which was, of course, occupied by a car that was pulling
out. By the grace of $diety, I managed to squeeze past her car into the spot she passed
up. By the time I was in the store, she was still parking her car.
Nakedness
Contrary to rumors, and to what you might infer from my [pictures page](chpic_idx.html), I do not trade pictures of naked people.
Honestly, I really don’t have that many. It’s simply not something I care about. If you
really want to see people naked, your best bet is to go to an [event](http://xox.stanford.edu) [where](http://www.stanford.edu/group/columbae/) [people](http://www.stanford.edu/group/Synergy/) [are](http://www.baytobreakers.com/) [naked](http://www.stanford.edu/home/welcome/campus/quad.html) and se quita your
own ropa.
Svenska
Finally, I don’t speak Swedish. Really, I don’t. Many bona fide
Swedish people like to try holding little conversations with me. It just doesn’t work.
Actually, a few months ago I changed my Powerbook language to Swedish, so out of pure
necessity I’ve learned the words for things like “window,” “computer,” “printer,” etc.
But it’s simply not possible to hold a sensible conversion with just those words!
The default paper size on my Powerbook changed to A4 when I changed
the language to Swedish. I finally found a place on Veterans Blvd. in Redwood City that
sells decent quality A4 paper at a reasonable price: XPEDX. They’re in the yellow pages
under “Paper.” Metric envelopes are a bigger challenge. There is a Japanese stationery
store at the Town and Country Shopping Center which sells the cutest stationery, but no
standard metric envelopes.
| http://lindholm.jp/ |
<title>The Nintendo Classics Archive » The truck have started to move!</title>
<link rel="stylesheet" type="text/css" href="front.css">
<link rel="icon" href="favicon.png" type="image/png">
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<Br>
<br>
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<td class="contents" width="20%">
<div class="contheader"><img src="gfx/bullet.gif">Site Info</div>
<a href="updates.htm" class="contents">Past Updates</a><br>
<a href="links.htm" class="contents">Links Elsewhere</a><br>
<br>
<p><div class="contheader"><img src="gfx/bullet.gif">Database</div>
<a href="reviews.htm" class="contents">Review Library</a><Br>
<a href="company.htm" class="contents">Game Companies</a><br>
<a href="access.htm" class="contents">Weird Accessories</a><br>
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<a href="faq.htm" class="contents">Frequent Queries</a><br><br>
<p><div class="contheader"><img src="gfx/bullet.gif">Interaction</div>
<a href="http://www.nesworld.com/cgi-bin/yabb/YaBB.pl" target="_blank" class="contents">Message Board</a><br>
<a href="http://tnca.myrmid.com/poll/poll.php?action=showpoll&pollid=1" class="contents">Poll 'o the Moment</a><br><br>
<p><div class="contheader" class="contents"><img src="gfx/bullet.gif">Leftovers</div>
<a href="other.htm" class="contents">Assorted Junk</a><Br>
<!-- <a href="never.htm" class="contents">We Never Made It</a><br> -->
<a href="music.htm" class="contents">Kickass Tunes</a>
</td>
<td class="news" width="75%">
<img src="gfx/news.gif">
<p>Welcome to TNCA, my ancient bit of space on the web dedicated to my favorite video game console, the Nintendo Entertainment System. Beginning in those intrepid Web 1.0 days of 1998, I put quite a bit of work into this site, some it good, some of it laughable, but it's all here for quaint posterity. Poke around, learn, chuckle, whatever. Y'know.
<p>Thanks for reading.
<p>—Sappy
</td>
</tr>
</table>
<center>
<div class="footer">
<p>© 1998-2005
<br><a href="http://www.myrmid.net">King JD</a> rocks your world.</p>
</div>
| The Nintendo Classics Archive » The truck have started to move!
![](gfx/logo-anim.gif)
| | |
| --- | --- |
| Site Info
[Past Updates](updates.htm)
[Links Elsewhere](links.htm)
Database
[Review Library](reviews.htm)
[Game Companies](company.htm)
[Weird Accessories](access.htm)
[Interesting Articles](articles.htm)
[Frequent Queries](faq.htm)
Interaction
[Message Board](http://www.nesworld.com/cgi-bin/yabb/YaBB.pl)
[Poll 'o the Moment](http://tnca.myrmid.com/poll/poll.php?action=showpoll&pollid=1)
Leftovers
[Assorted Junk](other.htm)
[Kickass Tunes](music.htm)
|
Welcome to TNCA, my ancient bit of space on the web dedicated to my favorite video game console, the Nintendo Entertainment System. Beginning in those intrepid Web 1.0 days of 1998, I put quite a bit of work into this site, some it good, some of it laughable, but it's all here for quaint posterity. Poke around, learn, chuckle, whatever. Y'know.
Thanks for reading.
—Sappy
|
© 1998-2005
[King JD](http://www.myrmid.net) rocks your world.
| http://tnca.myrmid.com/ |
<html>
<head>
<meta http-equiv="Content-Type" content="text/html; charset=windows-1252">
<meta http-equiv="Content-Language" content="en-gb">
<meta http-equiv="keywords" content="pets, dogs, horses, cats, birds, fish, rabbits,
siamese cats, labradors, alsations, german shepherds, old english sheepdog, great dane,
mongrels, puppies, red point, seal point, blue point, chocolate point, anglo-arab, pacer,
canary, budgie">
<meta name="GENERATOR" content="Microsoft FrontPage 4.0">
<meta name="keywords" content="the pet site,thepetsite,pets, dogs, horses, cats, birds, fish, rabbits, siamese cats,
labradors, alsations, german shepherds, old english sheepdog, great dane, mongrels,
puppies, red point, seal point, blue point, chocolate point, anglo-arab, pacer, canary, budgie">
<meta name="ProgId" content="FrontPage.Editor.Document">
<title>The Pet Site</title>
<meta name="Microsoft Border" content="none, default">
</head>
<body background="images/background.jpg">
<h1 align="center"><img border="0" src="images/index.html_txt_banner.gif" alt="The Pet Site" width="600" height="60"></h1>
<p> </p>
<p align="center">
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<param name="textcolor" value="#000000">
</applet>
<applet code="fphover.class" codebase="./" width="91" height="24">
<param name="text" value="Cats">
<param name="effect" value="glow">
<param name="url" valuetype="ref" value="cats.htm">
<param name="image" valuetype="ref" value="images/button.gif">
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<param name="textcolor" value="#000000">
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<param name="color" value="#000080">
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<applet code="fphover.class" codebase="./" width="92" height="24">
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</applet>
</p>
<p align="center"> </p>
<div align="center">
<center>
<table border="0" width="80%">
<tr>
<td width="100%" align="center"><font face="Arial" size="4" color="#800000">This
site shows a few of the different pets I have had over the years. We
somehow managed to combine travelling with breeding dogs, and showing
cats and horses. None of
them are alive now, unfortunately, as they were in another life, another
country and in another time.</font>
</td>
</tr>
</table>
</center>
</div>
<p align="center"><a href="dogs.htm"><br>
<font face="Bauhaus 93" size="2">Dogs</font></a><font size="2">
<a href="cats.htm"><font face="Bauhaus 93">Cats</font></a>
<a href="horses.htm"><font face="Bauhaus 93">Horses</font></a>
<a href="miscellaneous.htm"><font face="Bauhaus 93">Miscellany</font></a>
<a href="travel.htm"><font face="Bauhaus 93">Travel</font><br>
</a></font></p>
<p align="center"><font size="1">Designed by <a href="mailto:hrc@delhaven.co.uk">hrcdelhaven.co.uk</a></font></p>
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|
The Pet Site
# The Pet Site
| |
| --- |
| This
site shows a few of the different pets I have had over the years. We
somehow managed to combine travelling with breeding dogs, and showing
cats and horses. None of
them are alive now, unfortunately, as they were in another life, another
country and in another time. |
[Dogs](dogs.htm)
[Cats](cats.htm)
[Horses](horses.htm)
[Miscellany](miscellaneous.htm)
[Travel](travel.htm)
Designed by [hrcdelhaven.co.uk](mailto:hrc@delhaven.co.uk)
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consciousness</a> — concern for the planet as a whole. A subgoal is to teach people to use <a class="bgloss" href="bgloss/bgloss.html">computers</a> effectively, particularly with the <a class="jgloss" href="jgloss/jgloss.html">Java</a> computer language.</div></td></tr>
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The image in the top left corner is <a class="com" href="http://theimmoralminority.blogspot.ca/2015/02/only-49-of-republicans-believe-in.html">Bill W. cofounder of
AA</a>.
<h2><!-- macro Acronym AA_alcoholics --><!-- generated --><a class="acronymdef org" href="http://www.aa.org">AA</a> (<span class="means"><span class="ac">A</span>lcoholics <span class="ac">A</span>nonymous</span>)<!-- /generated by Acronym --></h2>
<p>Christians cite <!-- macro Acronym AA_alcoholics --><!-- generated --><span class="acronym"><abbr title="Alcoholics Anonymous">AA</abbr></span><!-- /generated by Acronym --> as evidence of Yahweh’s existence
because he reliably cures alcoholics. Lots of people show up on <!-- macro Acronym AA_alcoholics --><!-- generated --><span class="acronym"><abbr title="Alcoholics Anonymous">AA</abbr></span><!-- /generated by Acronym -->
’s door step who cannot stomach the notion of god. <!-- macro Acronym AA_alcoholics --><!-- generated --><span class="acronym"><abbr title="Alcoholics Anonymous">AA</abbr></span><!-- /generated by Acronym --> cheerily tells them to use anything they want as their <span class="scare">higher
power</span>, even a tree. It will work just fine. It works by creating a less cocky over-confident attitude, not
by divine intervention. The real secret is the endless meetings where people can socialise, tell stories about
getting drunk, smoke, drink coffee and eat cheap sugary cakes without the temptation of alcohol.</p>
<!-- /featuredposter --></div><!-- xxx Include include googlebitchmindprod.htmlfrag -->
<div class="quoteincol"><!-- macro Quotation general --><!-- generated --><blockquote class="roedy"><!-- added 2012-12-31 -->
<h2>America Fears Invasion, Get Serious!</h2>
<p>Americans tell me they are killing people in Iraq because if they don’t kill them there, they will have to
fight them back in America. America attacked Iraq in the Gulf war, in the sanction bombings and in the Iraq war.
Never in all that time did Iraqis attack American civilians, just the soldiers illegally invading their country.
The Americans killed about <span class="stat">3</span> million Iraqis. Thus the Iraqis have plenty of justification
for levelling the USA. Americans must take responsibility for creating that revenge motive through their
unconscionable treatment of the Iraqis, including torture, rape, murder and deaths too hideous to describe.
Americans attacked first, unprovoked and illegally. Even Bush said Iraq had nothing to do with <span class="x911">2001-09-11</span>. Americans use this phony fear excuse to cover for the real motive for the war, that
everyone but the Americans acknowledges, theft of the Iraqi oil reserves. The American excuse is as preposterous as
a mugger who stole money then beat his unarmed victims to a pulp killing them, then claiming self-defence.</p>
~ <span class="quoth">Roedy</span> <span class="unobtrusive">(<span class="birthdate">1948-02-04</span> age:<span class="age">70</span>)</span></blockquote><!-- /generated by Quotation --></div>
<div class="quoteincol"><!-- macro Quotation general --><!-- generated --><blockquote class="roedy"><!-- added 2017-08-07 -->
<h2>Faith</h2>
<p>Christians tell us they have no evidence that Yahweh exists or that the teachings of the church are true. We
must take them on faith. Doing this without question is a highly wise and virtuous thing to do. If you must accept
god by faith, then surely accepting other things by faith is a good idea too like: holocaust deniers, climate
change deniers, flat earthers, homeopathy, anti-vaxers, Christian Scientists, Bernie Madoff, Donald Trump, cold
fusion, perpetual motion machines, cars that run on water, eternal life… Maybe the same reason
faith/gullibility is not a good idea in the real world is the same reason you should not be so gullible about
religion and taking on faith whatever the Christian salesmen tell you. It is the nature of all con men (religious
or secular) to talk you into having faith and to act huffy when you doubt them.</p>
~ <span class="quoth">Roedy</span> <span class="unobtrusive">(<span class="birthdate">1948-02-04</span> age:<span class="age">70</span>)</span></blockquote><!-- /generated by Quotation --></div>
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Canadian Mind Products Introduction| CMP (Canadian Mind Products)’s purpose is to stand up for the rights of
plants and animals. *Animals* also includes [cetacea](animalrights/animalrights.html), [humans](humanrights/humanrights.html), [gay people](ggloss/ggloss.html),
[atheists](religion/religion.html), [war victims](politics/politics.html) and invertebrates. CMP
attempts to inculcate [planetary
consciousness](environment/environment.html) — concern for the planet as a whole. A subgoal is to teach people to use [computers](bgloss/bgloss.html) effectively, particularly with the [Java](jgloss/jgloss.html) computer language. |
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|
The image in the top left corner is [Bill W. cofounder of
AA](http://theimmoralminority.blogspot.ca/2015/02/only-49-of-republicans-believe-in.html).
## [AA](http://www.aa.org) (Alcoholics Anonymous)
Christians cite AA as evidence of Yahweh’s existence
because he reliably cures alcoholics. Lots of people show up on AA
’s door step who cannot stomach the notion of god. AA cheerily tells them to use anything they want as their higher
power, even a tree. It will work just fine. It works by creating a less cocky over-confident attitude, not
by divine intervention. The real secret is the endless meetings where people can socialise, tell stories about
getting drunk, smoke, drink coffee and eat cheap sugary cakes without the temptation of alcohol.
>
> ## America Fears Invasion, Get Serious!
>
>
> Americans tell me they are killing people in Iraq because if they don’t kill them there, they will have to
> fight them back in America. America attacked Iraq in the Gulf war, in the sanction bombings and in the Iraq war.
> Never in all that time did Iraqis attack American civilians, just the soldiers illegally invading their country.
> The Americans killed about 3 million Iraqis. Thus the Iraqis have plenty of justification
> for levelling the USA. Americans must take responsibility for creating that revenge motive through their
> unconscionable treatment of the Iraqis, including torture, rape, murder and deaths too hideous to describe.
> Americans attacked first, unprovoked and illegally. Even Bush said Iraq had nothing to do with 2001-09-11. Americans use this phony fear excuse to cover for the real motive for the war, that
> everyone but the Americans acknowledges, theft of the Iraqi oil reserves. The American excuse is as preposterous as
> a mugger who stole money then beat his unarmed victims to a pulp killing them, then claiming self-defence.
>
>
> ~ Roedy (1948-02-04 age:70)
>
> ## Faith
>
>
> Christians tell us they have no evidence that Yahweh exists or that the teachings of the church are true. We
> must take them on faith. Doing this without question is a highly wise and virtuous thing to do. If you must accept
> god by faith, then surely accepting other things by faith is a good idea too like: holocaust deniers, climate
> change deniers, flat earthers, homeopathy, anti-vaxers, Christian Scientists, Bernie Madoff, Donald Trump, cold
> fusion, perpetual motion machines, cars that run on water, eternal life… Maybe the same reason
> faith/gullibility is not a good idea in the real world is the same reason you should not be so gullible about
> religion and taking on faith whatever the Christian salesmen tell you. It is the nature of all con men (religious
> or secular) to talk you into having faith and to act huffy when you doubt them.
>
>
> ~ Roedy (1948-02-04 age:70)
> Please feel free to use any of the quotations or public service ads on the mindprod.com site on your own website, blog or social media page.
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<meta name="viewport" content="width=device-width, initial-scale=0.8"><title>Dandelion (Taraxacum officinale)</title></head>
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<p align="center"><font face="Tahoma" size="+2"><b><font color="#33cc33">Dandelion</font></b></font><br>
<i>Taraxacum officinale</i><br>
Aster family (Asteraceae)</p>
<blockquote>
<p><b><font color="#33cc33">Description:</font></b>
This
herbaceous perennial plant consists of a rosette of basal leaves and
occasional flowering stalks. The basal leaves are individually up to
10" long and 2½" across. The typical basal leaf is broader toward its
outer tip than at the base (oblanceolate) in outline, although it is
more or less lobed (pinnatifid) along its length. These lobes are
triangular. The margins are slightly wavy and irregular, and sometimes
coarsely dentate. There is a prominent central vein along the length of
each leaf that is hollow and contains milky juice. This vein is usually
green, but it sometimes becomes reddish green toward the base. The
leaves are usually hairless, although young leaves are sometimes
slightly pubescent. From the center of the rosette, one or more
flowering stalks are produced that are up to 18" tall, although usually
12" or less. Each slender stalk is round and hollow, and contains milky
juice. It is usually light green, sometimes becoming light reddish
green toward the base. There may be some appressed cobwebby hairs along
its length. At the apex of each flowering stalk, there is a single
yellow flowerhead about 1-2" across. </p>
<p style="text-align: center;"><img style="width: 435px; height: auto; max-width: 100%;" title="Flowering Plant" src="../photos/dandelion1.jpg"></p>
<p>This flowerhead
has about 150-200 yellow ray florets and no disk florets; the ray
florets spread outward from the center. At the base of the flowerhead,
there are inner and outer bracts that are green. The inner bracts are
linear or linear-lanceolate and appressed together to form a
cylindrical tube around the ovaries of the flowerhead. The outer bracts
are linear-lanceolate and sharply curve downward. The flowerheads are
produced sporadically from early spring to late fall; they are most
like to occur during the late spring or early summer. There is a
pleasant floral scent that is somewhat musty and pollen-laden. Each ray
floret produces a single slender achene that is light brown, light
gray, or slightly olive green. An achene has 5-10 longitudinal ribs
with tiny teeth toward its apex. A long slender beak connects the
achene with a tuft of white hairs. This beak is 2-3 times as long as
the achene. Collectively, these tufts of hair produce a spheroid mass
that is white and feathery in appearance. The achenes are dispersed by
the wind. The root system consists of a stout taproot that is up to 3'
long (if not more). This taproot contains milky juice and is somewhat
fleshy. This plant spreads by reseeding itself. It can form large
colonies.<br>
<br>
<b><font color="#33cc33">Cultivation:</font></b>
The preference is full sunlight, mesic conditions, and a soil that
consists of loam or clay-loam. Partial sunlight is also tolerated. This
plant can be very aggressive, and it can regenerate from small pieces
of
the taproot.</p>
<p style="text-align: center;"><img style="width: 450px; height: auto; max-width: 100%;" title="Flowerhead & Bee" src="../photos/dandelion2.jpg"></p>
<p><b><font color="#33cc33">Range &
Habitat:</font></b>
Dandelion is a very common plant that occurs in every county of
Illinois (see <a href="../maps/map2.htm" target="map" onclick="window.open('','map','resizable=no,scrollbars=no,height=463,width=275,left=100,screenX=100,top=50,screenY=50')">Distribution
Map</a>). It was introduced to North America from Europe.
Habitats include lawns, gardens, degraded meadows, vacant lots, and
sunny areas along roads and railroads. Dandelion has little capacity to
invade high quality natural habitats, always preferring open areas that
are disturbed and degraded by human-related activities.<br>
<br>
<b><font color="#33cc33">Faunal Associations:</font></b>
The nectar and pollen of the flowerheads primarily attract long-tongued
bees, short-tongued bees, and bee flies. Among the bees, are such
visitors as bumblebees, honeybees, mason bees, Halictid bees, and
Andrenid bees. Less often, butterflies and skippers suck nectar from
the flowerheads, while occasional beetles feed on the pollen. The
foliage, seeds, roots, and other parts of Dandelion (Taraxacum
officinale) are eaten by many kinds of
insects, including adult ground beetles (seeds), aphids (primarily
roots), mealybugs (primarily foliage), the larvae of many moths
(primarily foliage), and grasshoppers (primarily foliage). The <a name="insects"></a><a href="../tables/table11.html">Insect
Table</a> provides a more complete list of these insect feeders. Among
vertebrate animals, such songbirds as the Indigo Bunting, Chipping
Sparrow, and American Goldfinch eat the seeds, while such upland
gamebirds as the Ruffed Grouse, Hungarian Partridge, and Greater
Prairie Chicken eat the leaves and/or seeds (Martin et al., 1951/1961;
DeVore et al., 2004). Because of its white latex, the foliage of
Dandelion is somewhat bitter. Nonetheless, it is consumed by the
Prairie Vole, Meadow Vole, and Woodland Vole (which may also eat the
roots); the Groundhog, White-tailed Deer, and domesticated livestock
also eat the foliage occasionally (Cole & Batzli, 1979; Lindroth
& Batzli, 1984; Martin et al., 1951/1961). The American Black Bear
eats both the foliage and flowerheads of Dandelion, while the
Thirteen-lined Ground Squirrel eats its flowerheads and seeds
(Whitaker, 1972; Romain et al., 2013; Mosnier et al., 2008). Somewhat
surprisingly, both the Wood Turtle and Ornate Box Turtle have been
observed to feed on the leaves of this plant as well (Lagler, 1943;
Ernst et al., 1994).<br>
<br>
<b><font color="#33cc33">Photographic Location:</font></b>
At the apartment complex of the webmaster in Urbana, Illinois.</p>
<p style="text-align: center;"><img style="width: 580px; height: auto; max-width: 100%;" title="Flowering Stalks & Leaves" src="../photos/dandelion3.jpg"></p>
<p><b><font color="#33cc33">Comments:</font></b>
The young
leaves of Dandelion are sometimes used fresh in salads, or boiled as a
potherb. When the flowerheads develop, the foliage becomes increasingly
bitter and tough. The leaves are high in vitamins and minerals.
Sometimes the flowerheads are used to make dandelion wine. Most people
regard Dandelion as a pernicious weed (with some justification), even
though the flowers are quite attractive. Because it can bloom very
early or very late in the year, the nectar or pollen of the flowerheads
are a valuable source of food to some pollinating insects, especially
bees. There are many members of the Aster family that produce a rosette
of leaves with stalks of flowerheads that consist entirely of yellow
ray florets. As a result, people sometimes confuse other species in
this group with Dandelion. Dandelion has the following characteristics
that may be useful in making a correct identification: 1) the outer
green bracts curve sharply downward from the flowerheads, 2) only a
single flowerhead is produced from a hollow flowering stalk, and 3) the
outermost lobe of each leaf is the largest. There is also another
dandelion species, <i>Taraxacum erythrospermum</i>
(Red-Seeded Dandelion) that sometimes occurs in Illinois. This species
has achenes that are reddish brown and its leaves are more deeply
pinnatifid than the typical Dandelion. Also, the slender beak
connecting the achene with its tuft of hair is shorter (up to twice the
length of the achene) in this species than the beak of the typical
Dandelion (2-3 times as long as the achene).</p>
</blockquote>
<p align="center"><a href="../weed_index.htm#dandelion">Return</a></p>
<br>
</font>
</body></html> |
Dandelion (Taraxacum officinale)
**Dandelion**
*Taraxacum officinale*
Aster family (Asteraceae)
>
> **Description:**
> This
> herbaceous perennial plant consists of a rosette of basal leaves and
> occasional flowering stalks. The basal leaves are individually up to
> 10" long and 2½" across. The typical basal leaf is broader toward its
> outer tip than at the base (oblanceolate) in outline, although it is
> more or less lobed (pinnatifid) along its length. These lobes are
> triangular. The margins are slightly wavy and irregular, and sometimes
> coarsely dentate. There is a prominent central vein along the length of
> each leaf that is hollow and contains milky juice. This vein is usually
> green, but it sometimes becomes reddish green toward the base. The
> leaves are usually hairless, although young leaves are sometimes
> slightly pubescent. From the center of the rosette, one or more
> flowering stalks are produced that are up to 18" tall, although usually
> 12" or less. Each slender stalk is round and hollow, and contains milky
> juice. It is usually light green, sometimes becoming light reddish
> green toward the base. There may be some appressed cobwebby hairs along
> its length. At the apex of each flowering stalk, there is a single
> yellow flowerhead about 1-2" across.
>
>
> ![](../photos/dandelion1.jpg "Flowering Plant")
>
>
> This flowerhead
> has about 150-200 yellow ray florets and no disk florets; the ray
> florets spread outward from the center. At the base of the flowerhead,
> there are inner and outer bracts that are green. The inner bracts are
> linear or linear-lanceolate and appressed together to form a
> cylindrical tube around the ovaries of the flowerhead. The outer bracts
> are linear-lanceolate and sharply curve downward. The flowerheads are
> produced sporadically from early spring to late fall; they are most
> like to occur during the late spring or early summer. There is a
> pleasant floral scent that is somewhat musty and pollen-laden. Each ray
> floret produces a single slender achene that is light brown, light
> gray, or slightly olive green. An achene has 5-10 longitudinal ribs
> with tiny teeth toward its apex. A long slender beak connects the
> achene with a tuft of white hairs. This beak is 2-3 times as long as
> the achene. Collectively, these tufts of hair produce a spheroid mass
> that is white and feathery in appearance. The achenes are dispersed by
> the wind. The root system consists of a stout taproot that is up to 3'
> long (if not more). This taproot contains milky juice and is somewhat
> fleshy. This plant spreads by reseeding itself. It can form large
> colonies.
>
>
>
> **Cultivation:**
> The preference is full sunlight, mesic conditions, and a soil that
> consists of loam or clay-loam. Partial sunlight is also tolerated. This
> plant can be very aggressive, and it can regenerate from small pieces
> of
> the taproot.
>
>
> ![](../photos/dandelion2.jpg "Flowerhead & Bee")
>
>
> **Range &
> Habitat:**
> Dandelion is a very common plant that occurs in every county of
> Illinois (see [Distribution
> Map](../maps/map2.htm)). It was introduced to North America from Europe.
> Habitats include lawns, gardens, degraded meadows, vacant lots, and
> sunny areas along roads and railroads. Dandelion has little capacity to
> invade high quality natural habitats, always preferring open areas that
> are disturbed and degraded by human-related activities.
>
>
>
> **Faunal Associations:**
> The nectar and pollen of the flowerheads primarily attract long-tongued
> bees, short-tongued bees, and bee flies. Among the bees, are such
> visitors as bumblebees, honeybees, mason bees, Halictid bees, and
> Andrenid bees. Less often, butterflies and skippers suck nectar from
> the flowerheads, while occasional beetles feed on the pollen. The
> foliage, seeds, roots, and other parts of Dandelion (Taraxacum
> officinale) are eaten by many kinds of
> insects, including adult ground beetles (seeds), aphids (primarily
> roots), mealybugs (primarily foliage), the larvae of many moths
> (primarily foliage), and grasshoppers (primarily foliage). The [Insect
> Table](../tables/table11.html) provides a more complete list of these insect feeders. Among
> vertebrate animals, such songbirds as the Indigo Bunting, Chipping
> Sparrow, and American Goldfinch eat the seeds, while such upland
> gamebirds as the Ruffed Grouse, Hungarian Partridge, and Greater
> Prairie Chicken eat the leaves and/or seeds (Martin et al., 1951/1961;
> DeVore et al., 2004). Because of its white latex, the foliage of
> Dandelion is somewhat bitter. Nonetheless, it is consumed by the
> Prairie Vole, Meadow Vole, and Woodland Vole (which may also eat the
> roots); the Groundhog, White-tailed Deer, and domesticated livestock
> also eat the foliage occasionally (Cole & Batzli, 1979; Lindroth
> & Batzli, 1984; Martin et al., 1951/1961). The American Black Bear
> eats both the foliage and flowerheads of Dandelion, while the
> Thirteen-lined Ground Squirrel eats its flowerheads and seeds
> (Whitaker, 1972; Romain et al., 2013; Mosnier et al., 2008). Somewhat
> surprisingly, both the Wood Turtle and Ornate Box Turtle have been
> observed to feed on the leaves of this plant as well (Lagler, 1943;
> Ernst et al., 1994).
>
>
>
> **Photographic Location:**
> At the apartment complex of the webmaster in Urbana, Illinois.
>
>
> ![](../photos/dandelion3.jpg "Flowering Stalks & Leaves")
>
>
> **Comments:**
> The young
> leaves of Dandelion are sometimes used fresh in salads, or boiled as a
> potherb. When the flowerheads develop, the foliage becomes increasingly
> bitter and tough. The leaves are high in vitamins and minerals.
> Sometimes the flowerheads are used to make dandelion wine. Most people
> regard Dandelion as a pernicious weed (with some justification), even
> though the flowers are quite attractive. Because it can bloom very
> early or very late in the year, the nectar or pollen of the flowerheads
> are a valuable source of food to some pollinating insects, especially
> bees. There are many members of the Aster family that produce a rosette
> of leaves with stalks of flowerheads that consist entirely of yellow
> ray florets. As a result, people sometimes confuse other species in
> this group with Dandelion. Dandelion has the following characteristics
> that may be useful in making a correct identification: 1) the outer
> green bracts curve sharply downward from the flowerheads, 2) only a
> single flowerhead is produced from a hollow flowering stalk, and 3) the
> outermost lobe of each leaf is the largest. There is also another
> dandelion species, *Taraxacum erythrospermum*
> (Red-Seeded Dandelion) that sometimes occurs in Illinois. This species
> has achenes that are reddish brown and its leaves are more deeply
> pinnatifid than the typical Dandelion. Also, the slender beak
> connecting the achene with its tuft of hair is shorter (up to twice the
> length of the achene) in this species than the beak of the typical
> Dandelion (2-3 times as long as the achene).
>
>
>
[Return](../weed_index.htm#dandelion)
| http://www.illinoiswildflowers.info/weeds/plants/dandelion.htm |