AmaNdwandwe angabantu abakhuluma isiBantu Nguni abagcwalisa izingxenye zeningizimu ye- Afrika. AmaNdwandwe, kanye nabakwaMthethwa, babengamandla amakhulu eZululand yanamuhla ekuqaleni kwekhulu leshumi nesishiyagalolunye. Ngaphansi kobuholi beNkosi uZwide, isizwe sakwaNdwandwe sabhubhisa abakwaMthethwa ngaphansi kwenkosi yabo uDingiswayo, futhi isikhala sombuso sagcwaliswa uShaka Zulu nesizwe samaZulu.Ngokuphikisana okufanayo namaNdwandwe, uShaka waqoqa izinsalela zaMthethwa nezinye izizwe zesifunda, wasinda ekulweni kokuqala kweMpi Yombango kaZulu noZwide e- Battle of Gqokli Hill ngo-1818. Ngo-1819, uZwide wenza omunye umkhankaso wokulwa namaZulu, kodwa uShaka waphinde washintsha amaqhinga akhe, wavumela ibutho lakwaNdwandwe ukuba lingene endaweni yakhe futhi liphendule ngempi yabashokobezi.Ukushoda kwempahla kwabangela ukuba i-Ndandwe ibuyele ekhaya, kepha ngenkathi bewela umfula uMhlatuze ekuqaleni kuka-1820, amabutho abo ahlukana futhi anqotshwa eMfuleni iMhlatuze River. Lokhu kwaholela ekuhlakazekeni kwesizwe samaNdwandwe njengoba ojenene bakaZwide namadodana akhe babehola izingxenye zeNdwandwe ngasenyakatho.Elinye iqembu elinjalo, ngaphansi kukaSoshangane, lasungula iGaza Empire enkabeni yeMozambique yanamuhla kanti elinye, ngaphansi kukaZwangendaba, lasungula umbuso njenge-waNgoni eMalawi yanamuhla.