I-Penectomy ukususwa kwenduku ngokuhlinzwa, imvamisa ngezizathu zezokwelapha noma zomuntu siqu. Umdlavuza, isibonelo, kwesinye isikhathi kudinga ukuthi kususwe ingxenye noma wonke umthondo. Inani lobudoda elikhishiwe lincike ebucayi bomdlavuza.Amanye amadoda asuswe kuphela ichopho lomthondo.Kwabanye abanomdlavuza osuthuthuke kakhulu, wonke umthondo kufanele ususwe. Ezimweni ezingavamile, ukusokwa okushintshiwe nakho kuholele ekupheleleni okuphelele noma okuyingxenye, njengoDavid Reimer. I-Fournier gangrene ingaba yisizathu se-penectomy kanye / noma i- orchiectomy . Ngenxa yokutholakala komdlavuza odinga ukususwa ngokwengxenye noma okuphelele kwenduku, ukusekelwa kwabantu abakhishwe ipipi kungaba nzima ukuthola endaweni.Amanethiwekhi wokusekelwa kwewebhusayithi ayatholakala.Isibonelo, iwebhusayithi ye-American Cancer Society's Cancer Survivors Network inikeza imininingwane yokuthola amanethiwekhi wokusekela.I-Phalloplasty nayo iyindlela yokwakha kabusha ipipi. Iziguli ezenze i-penectomy engaphelele ngenxa yokuxilongwa komdlavuza womthondo zibike imiphumela efanayo yezocansi ngaphambi kokuhlinzwa. Abelaphi bezokwelapha nabachwepheshe bayatholakala kuzwelonke e-United States futhi bangafinyeleleka ngezinsizakalo zomdlavuza ezikhethekile.Odokotela abaningi abahlinzayo noma izibhedlela bazohlinzeka lolu lwazi ngokusebenza.Iminyango yezinsizakalo zezempilo kahulumeni wasekhaya ingakwazi ukunikeza izeluleko, amagama, nezinombolo zokuxhumana. "Partial Penectomy for Patients With Squamous Cell Carcinoma of the Penis: The Memorial Sloan-Kettering Experience". Annals of Surgical Oncology 14 (12): 3614–3619. doi:10.1245/s10434-007-9563-9. PMID 17896151.