UZanele Mbeki ( née Dlamini ; owazalwa ngomhlaka 18 Novemba 1938) ungusonhlalonhle waseNingizimu Afrika owasekela iBhange Lwabesifazane Lokuthuthukiswa. Uphinde waba ngowesifazane wokuqala waseNingizimu Afrika. UZanele Dlamini wazalelwa e- Alexandra ngo-1938 lapho ubaba wakhe wayengumfundisi waseWeseli kanti umama wakhe wayengumthungi wezingubo.Unodadewabo abahlanu. UMbeki ubehlala ebhodini e-Catholic Inkamana Academy KwaZulu-Natal ngaphambi kokufundela ukuba ngusonhlalakahle e- University of Witwatersrand . Ngemuva kokusebenza iminyaka emithathu ku- Anglo American plc njengesisebenzi saseZambia, uMbeki wathuthela eLondon futhi waqeda idiploma yenqubomgomo yezenhlalakahle nokuphatha eLondon School of Economics ngo-1968. Kamuva wazuza umfundaze wokwenza i-PhD yakhe esikhundleni sabesifazane base-Afrika ngaphansi kobandlululo eBrandeis University eMelika, yize ashiya eMelika eyoshada noThabo Mbeki ngaphambi kokukuphothula. Ngenkathi eseLondon, uMbeki wasebenza njengonhlalonhle wezifo zengqondo esibhedlela saseGuy, naseMarlborough Day Hospital . UMbeki wahlangana noThabo Mbeki esafunda e-University of London futhi babeshade ehhovisi lokubhalisa eLondon ngomhlaka 23 Novemba 1974, kwalandelwa umcimbi wenkolo ekhaya likadadewabo omdala u-Edith, eFarnham Castle eSurrey.Kwakudingeka athole imvume ku-ANC yokuthi ashade futhi kubikwa ukuthi watshela u- Adelaide Tambo "uma uPapa [ Oliver Tambo ] engangivumeli ukuba ngishade noZanele, angisoze, ngiphinde ngishade.