USiphokazi Mani-Lusithi (owazalwa ngomhlaka 19 kuJulayi 1986) ungusopolitiki waseNingizimu Afrika, njengamanje oyilungu lesiShayamthetho sesiFundazwe saseMpumalanga Kapa se- African National Congress, futhi oseyiLungu loMkhandlu oPhethe (MEC) njengamanje elibhekele ezokuThuthukiswa koMphakathi e- Eastern Cape uhulumeni wesifundazwe . UMani-Lusithi wazalwa ngomhlaka 19 Julayi 1986 eSteynsburg esifundazweni esasiyiCape Cape . Ufunde u-matric eLawson Brown High School ePort Elizabeth ngo-2003. Ufunde e- University of Port Elizabeth nase- University of Fort Hare .Njengamanje wenza iziqu zeBachelor of Administration azithola e- University of South Africa . UMani-Lusithi ubebambe iqhaza kwi- African National Congress Youth League, iYoung Communist League yaseNingizimu Afrika, nezepolitiki yabafundi. Usebenze njengomgcinimafa wesifundazwe wophiko lwentsha lwe-ANC e-Eastern Cape nosihlalo wesifundazwe weSouth African Student Congress . Wayephinde abe yilungu leNational Executive Committee (NEC) yeYoung Communist League yaseNingizimu Afrika. UMani-Lusithi ubesebenza njengemenenja yesifundazwe ezindabeni zengqungquthela nezokhetho ehhovisi le-ANC lesifundazwe. Wayephinde abe ngumxhumanisi wekomidi elincane le-ANC PEC. Ngaphambi kokukhethwa kwakhe esiShayamthetho sesifundazwe, uMani-Lusithi ubesebenza kwa-HR ehhovisi le-ANC Caucus eSishayamthetho sesifundazwe.