I-Aphosithiya yisimo esingajwayelekile sokuzalwa kubantu, lapho ijwabu lobudoda alikho.  : 37–39  Ngasekupheleni kwekhulu leshumi nesishiyagalolunye, u- ES Talbot wathi i-aposthia phakathi kwamaJuda yayiwubufakazi benkolelo yokuziphendukela kwemvelo yaseLamarckian esehlisiwe . Encwadini yakhe ethi The Variation of Animals and Plants Under Domestication, uCharles Darwin uphinde wakhuluma ngamacala abantwana "abazelwe besokile" njengobufakazi obuqand 'ikhanda " befa elilahliwe manje. Kungenzeka ukuthi amacala awachazile empeleni ayengama-hypospadias, isimo lapho inyama yokuchama ingaphansi kwepipi. I Midrash ka Ki-Tetze [כי תצא] izimangalo uMose wazalelwa aposthic. Eminye imithombo  ukuthi uJakobe, indodana yakhe uGadi kanye neNkosi uDavid nabo bazalwa bengathandeki.Incwadi ethi Abot De-Rabbi Natan (Obaba NgokukaRabi Nathan) iqukethe uhlu lwabantu abavela emiBhalweni yakwa-Israyeli "abazalwa besokile": U-Adam, uSeti, uNowa, uShemi, uJakobe, uJoseph, uMose, uBhalami omubi, uSamuweli, David, Jeremiah noZerubabele.