UDesmond Dube (owazalwa ngomhla ka-27 Novemba 1969) ungumculi waseNingizimu Afrika, umlingisi, umculi we-mime futhi ungcebeleka.Uyaziwa ngomsebenzi wakhe kwiThe No 1 Ladies 'Detective Agency, Hotel Rwanda, Friends Indeed, Suburban Bliss naseJoburg Blues . Ungumlingisi waseshashalazini oqeqeshiwe futhi uke wabonakala kuzo zombili ezentengiselwano nasesitaladini. Esiteji ubedlala phambili kuJozi Jozi, Peto nakwiStreet Sisters, waphinde wabonakala emdlalweni weshashalazi ongamukelwanga kahle uJoseph kanye ne-Amazing Technicolor Dreamcoat.Uvele emidlalweni yeshashalazi yezimboni ka- Eskom, uSiyabonga ne- AIDS Show . Waziwa kakhulu  Indima yakhe ethi " Amaglugglug " commercial for Sasol . UDube ubelingisa efilimini efakiwe ethi Inside and Tarzan: The Epic Adventures, waphinde wadlala noLeon Schuster kwiPanic Mechanic neMillennium Menace . Ngo-2002, walingisa okuphambene nomqokiwe we- Oscar u-Armin Mueller-Stahl noNthati Moshesh ku- The Long Run, eyayikhishwa ngu- Anant Singh.Le filimu itholwe yi- Universal Focus, uphiko olukhethekile lwama- Universal Films ukuze lusatshalaliswe emhlabeni wonke ngaphandle kwe- Afrika . UDube ngoMsombuluko, ongomunye wemidlalo yamahlaya ethandwa kakhulu kuthelevishini eNingizimu Afrika, usakazwa kuSABC 3.Kubikwa ukuthi njengoba ithelevishini yaseNingizimu Afrika yokuqala ngemuva kwempelasonto "ishaye umdlalo wosomahlaya wangoMsombuluko blues" okhanga bonke abantu baseNingizimu Afrika.