Ukuphuka kwepenile ukuqhekeka kweyodwa noma zombili ze- tunica albuginea, izembozo ezinemicu emboza i- corpora cavernosa yepipi.Kubangelwa amandla asheshayo aqonde endondeni emile, imvamisa ngesikhathi sokuya ocansini, noma ukushaya indlwabu ngolaka.Kwesinye isikhathi kufaka nokuqhekeka okuyingxenye noma okuphelele kwe- urethra noma ukulimala kwezinzwa, imithambo nemithambo yegazi . Umsindo wokuqhuma noma wokuqhekeka, ubuhlungu obukhulu, ukuvuvukala, ukulahlekelwa ngokushesha kokwakhiwa okuholela ekuqothukeni, kanye ne- hematoma yesikhumba yamasayizi ahlukahlukene kuvame ukuhlotshaniswa nomcimbi wezocansi. Ukuphuka kwepenile yisimo somtholampilo esingajwayelekile. Ubulili besitho sangasese sowesilisa nokushaya indlwabu okunolaka kuyizimbangela ezivame kakhulu.Ucwaningo lwango-2014 lwamarekhodi ezingozi kanye nezimo eziphuthumayo ezibhedlela ezintathu eCampinas, eBrazil, lukhombisile ukuthi owesifazane osezikhundleni eziphezulu udale ingozi enkulu kakhulu ngokuthi isikhundla sezithunywa zevangeli sibe esiphephe kakhulu.Ucwaningo lubhekise ekutheni uma umlingani owamukelayo ephezulu, bavame ukulawula ukunyakaza futhi abakwazi ukuphazamisa ukunyakaza lapho ipipi lithola ukungena okungalungile.Ngakolunye uhlangothi, lapho umlingani ongena ngaphakathi elawula ukunyakaza, banamathuba angcono okuyeka ukuphendula ubuhlungu bokungalungiswa kahle, banciphise ukulimala. Umkhuba we- taqaandan (obuye abe ngu- taghaandan ) nawo ubeka abesilisa engcupheni yokuphuka i-penile.