I-esyN (Amanethiwekhi iyithuluzi lewebhu le- bioinformatics yokubona ngeso lengqondo, ukwakha nokuhlaziya amanethiwekhi wokuxhumana kwamangqamuzana.I-esyN isuselwa ku-cytoscape.js futhi inhloso yayo ukwenza kube lula ngawo wonke umuntu ukwenza ukuhlaziywa kwenethiwekhi. I-esyN ixhunyaniswe nemininingwane eminingi - ikakhulukazi: i-pombase, i- flybase, kanye nezinqolobane eziningi zedatha ye- InterMine , i-DrugBank, ne- BioGRID lapho kungenzeka khona ukulanda amaprotheni amaprotheni noma ukuhlangana kofuzo kwanoma iyiphi iprotheni noma isakhi sezinhlobo zezinto eziphilayo ezahlukahlukene. Amanethiwekhi ashicilelwe ku-esyN angashicilelwa kalula kwamanye amawebhusayithi kusetshenziswa indlela ye- <iframe>. Kusukela ngoJanuwari 2016 i-esyN ibukwa abasebenzisi abayingqayizivele abangu-1500 ngosuku (cishe i-16000 ngenyanga) ngokwe- Google Analytics. Amandla okushumeka we-esyN asetshenziswa ngenqwaba yolwazi ukukhombisa idatha yabo yokuxhumana: Bean (2014). "esyN: Network Building, Sharing and Publishing.". PLOS ONE 9 (9): e106035. doi:10.1371/journal.pone.0106035. PMC 4152123. PMID 25181461. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4152123.  Hoffman (2015). "An Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model System".