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drug_combination | What is the drug combination mentioned in the following sentence? Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat . | Ursodeoxycholic acid taurine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This study assessed the efficacy and safety of telaprevir in combination with peginterferon-α-2b ( PEG IFN ) and ribavirin ( RBV ) , for Japanese difficult-to-treat patients with hepatitis C virus ( HCV ) genotype 2 who had not achieved sustained virological response ( SVR ) during prior treatment . | telaprevir peginterferon-α-2b are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Combination of a betalactam antibiotic ( ampicillin or azlocillin ) or polymyxin B with rifampicin were studied with their administration in succession at various intervals in an experimental model of plague infection of albino mice . | ampicillin rifampicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Previous treatments with rituximab and with rituximab plus high dose glucocorticoids , as well as with cyclophosphamide , azathioprine , plasma exchange , hyperbaric therapy , VAC therapy , prostacyclin , mycophenolate mofetil and surgery , had previously failed . | rituximab glucocorticoids are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The decision to test a triple combination has led to the development of Fansimef , a fixed combination with tablets containing 250 mg mefloquine , 500 mg sulfadoxine and 25 mg pyrimethamine . | mefloquine sulfadoxine pyrimethamine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The aim of this study was to evaluate three active agents , bleomycin ( BLM ) , epirubicin and carboplatin in a new combination ( BECA ) in terms of feasibility , activity and toxicity in patients with recurrent and metastatic squamous cell carcinoma of the head and neck . | bleomycin epirubicin carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A phase II trial of cytarabine , cisplatin , and etoposide was conducted in 38 patients with refractory stage III and IV non-Hodgkin 's lymphoma . | cytarabine cisplatin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The combination of camrelizumab plus gemcitabine and cisplatin has a manageable toxicity profile and promising preliminary antitumour activity for this disease in treatment-naive patients . | camrelizumab gemcitabine cisplatin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? His infection failed to respond to combinations of surgery , fluconazole and itraconazole . | fluconazole itraconazole are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The protective effect of tianeptine against PTZ seizures was mitigated when tianeptine was administered with naloxone . | tianeptine naloxone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The sensitivity of human neuroblastoma-derived cell lines , cell line-derived , and patient-derived xenograft ( PDX ) models with varying ALK statuses to crizotinib combined with topotecan and cyclophosphamide ( topo/cyclo ) was examined . | crizotinib topotecan cyclophosphamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients were randomised to either receive additional tretinoin ( 45mg/m(2)/day ) for 12 weeks ( arm A ) , or peg-interferon and ribavirin alone ( arm B ) . | ribavirin peg-interferon are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This study sought to determine the efficacy and toxicity of weekly paclitaxel and carboplatin in CUP . | paclitaxel carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The patient achieved complete remission after two cycles of chemotherapy of daunorubicin , cytarabine and etoposide . | daunorubicin cytarabine etoposide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? This synergy was abrogated through siRNA knockdown of IkB. The synergistic effect of combining selinexor and bortezomib in vitro provides rationale for further investigation of this combination treatment for patients with high-risk neuroblastoma . | selinexor bortezomib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Therapy included 4 or 8 intensive therapy elements N1 ( Etoposide 125 mg/m2 day 1 - 4 , Vindesine 3 mg/m2 day 1 , Cisplatin 40 mg/m2 day 1 - 4 ) and N2 ( Vincristine 1.5 mg/m2 day 1 + 8 , Dacarbazine 200 mg/m2 day 1 - 5 , Ifosfamide 1500 mg/ m2 day 1 - 5 , Doxorubicin 30 mg/m2 day 6 + 7 ) in alternating order . | Etoposide Cisplatin Vindesine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Efficacy and safety of tacrolimus and low-dose prednisone in Chinese children with steroid-resistant nephrotic syndrome . | tacrolimus prednisone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Genistein reduced Bcl-2 phosphorylation triggered by paclitaxel and vincristine without changing Bax protein expression . | Genistein paclitaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? This Nordic multicenter phase II study evaluated the efficacy and safety of oxaliplatin combined with the Nordic bolus schedule of fluorouracil ( FU ) and folinic acid ( FA ) as first-line treatment in metastatic colorectal cancer . | oxaliplatin fluorouracil folinic acid are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In xenograft studies , the combination of trastuzumab plus letrozole is equally effective in inhibiting growth of MCF-7Ca tumors as letrozole alone . | trastuzumab letrozole are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The patient showed a substantial response to treatment with a combination of antimicrobial therapies consisting of clarithromycin , amikacin , and cefoxitin for 6 months . | clarithromycin amikacin cefoxitin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The methods have been utilized to evaluate the pharmacokinetics and bioavailability of oral dosage forms containing levodopa and carbidopa . | levodopa carbidopa are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Contribution of moxifloxacin or levofloxacin in second-line regimens with or without continuation of pyrazinamide in murine tuberculosis . | moxifloxacin pyrazinamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The addition of tamoxifen did not worsen the known side effects of gefitinib , or induce additional side effects . | tamoxifen gefitinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A topical combination of 0.25 % finasteride and 3 % minoxidil may be a promising option in the treatment of FPHL with an additional benefit of increasing hair diameter . | finasteride minoxidil are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Acute verapamil toxicity in a patient with chronic toxicity : possible interaction with ceftriaxone and clindamycin . | verapamil ceftriaxone clindamycin are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Eighty-three patients were treated with rituximab , cyclophosphamide , doxorubicin , vincristine , prednisone ( R-CHOP ) , 7 with rituximab , etoposide , cyclophosphamide , doxorubicin , vincristine , prednisone ( R-EPOCH ) , and 6 with R-CHOP with methotrexate , 3 g/m(2 ) . | rituximab cyclophosphamide doxorubicin vincristine prednisone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Among them , 18 ( 85.7 % ) patients had disease control with gefitinib and 12 ( 57.1 % ) patients with salvage erlotinib . | gefitinib erlotinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The combination of volasertib with pemetrexed did not improve efficacy compared with pemetrexed monotherapy . | volasertib pemetrexed are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A phase I/II study was carried out to determine the maximum tolerated dose of paclitaxel ( Taxol ; Bristol-Myers Squibb Company , Princeton , NJ ) in combination with a fixed dose of carboplatin ( area under the concentration-time curve = 6 by Calvert method ) given on an every-3-week schedule to patients with non-small cell lung cancer ( NSCLC ) . | paclitaxel carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? These results suggest that therapy with insulin plus dexamethasone but not therapy with leptin is beneficial for diabetics . | dexamethasone insulin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? This study investigated the efficacy and toxicity associated with consolidation chemotherapy using paclitaxel and carboplatin after concurrent chemoradiation ( CCR ) in cervical cancer patients . | paclitaxel carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Cladribine with Granulocyte Colony-Stimulating Factor , Cytarabine , and Aclarubicin Regimen in Refractory/Relapsed Acute Myeloid Leukemia : A Phase II Multicenter Study . | Cladribine Granulocyte Colony-Stimulating Factor Cytarabine Aclarubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Combining erlotinib with doxorubicin or docetaxel or SN-38 resulted in additive or even synergistic antiproliferative effects . | erlotinib doxorubicin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The present work is concerned with simultaneous determination of cefepime ( CEF ) and the co-administered drug , levofloxacin ( LEV ) , in spiked human plasma by applying a new approach , Savitzky-Golay differentiation filters , and combined trigonometric Fourier functions to their ratio spectra . | cefepime levofloxacin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Forthcoming data from phase 3 placebo-controlled trials of everolimus , one focused on monotherapy for pancreatic NET and the other on combination use with octreotide LAR for patients with advanced NET and a history of carcinoid syndrome , will provide insight into its future place in NET therapy . | everolimus octreotide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The effects of prednisone and azathioprine on circulating immunoglobulin levels and lymphocyte subpopulations in normal dogs . | prednisone azathioprine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The analytical range for dihydroartemisinin , dihydroartemisinin-glucuronide and artesunate was 10 - 1000 ng/ml and for artemether 90 - 3000 ng/ml with a lower limit of quantification of 10 and 90 ng/ml , respectively . | dihydroartemisinin dihydroartemisinin-glucuronide artesunate are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Amphotericin B MICs were reduced upon combination with rifabutin from a mean of 0.65 microg/ml to a mean of 0.16 microg/ml against Aspergillus , and from a mean of 0.97 microg/ml to a mean of 0.39 microLg/ml against Fusarium ( P < 0.000001 for both ) . | Amphotericin rifabutin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Neoadjuvant therapy with gemcitabine plus doxorubicin results in a high tumor response rate with moderate oral and hematologic toxicity . | gemcitabine doxorubicin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? In this parallel group , randomized , double-blind study , 301 PD patients , the majority with motor fluctuations , received entacapone ( 200 mg ) or placebo with each daily dose of standard or controlled-release ( CR ) levodopa . | entacapone levodopa are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Importance of adding neomycin to metronidazole for bowel preparation . | neomycin metronidazole are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A combination chemotherapy regimen containing mitomycin-C ( 10 mg/m2 , day 2 ) , vincristine ( 0.5 mg/m2 , days 1 and 4 ) , bleomycin ( 30 U QD , days 1 - -4 as a continuous intravenous infusion during courses one and two only ) , and cis-platinum ( 50 mg/m2 , days 1 and 22 ) was administered every 6 weeks to 14 evaluable patients with advanced ( i.e. , Stage IVB ) and/or recurrent squamous cell carcinoma of the cervix . | mitomycin-C vincristine bleomycin cis-platinum are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Co-injection of the lowest doses of levobupivacaine and lidocaine dramatically increased the paw withdrawal latency . | levobupivacaine lidocaine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Inflammatory breast cancer ( IBC ) is a rare , aggressive form of breast cancer associated with HER2 amplification , with high risk of metastasis and an estimated median survival of 2.9 y. We performed an open-label , single-arm phase II clinical trial ( ClinicalTrials.gov NCT01325428 ) to investigate the efficacy and safety of afatinib , an irreversible ErbB family inhibitor , alone and in combination with vinorelbine in patients with HER2-positive IBC . | afatinib vinorelbine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Carboplatin and paclitaxel versus cisplatin , paclitaxel and doxorubicin for first-line chemotherapy of advanced ovarian cancer : a Hellenic Cooperative Oncology Group ( HeCOG ) study . | Carboplatin paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? For susceptibility testing , DS-8587 exhibited more effective antibacterial activity when compared with ciprofloxacin and levofloxacin . | ciprofloxacin levofloxacin are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Since 1987 , we have evaluated carboplatin alone or in combination with etoposide in two separate phase II trials of patients with non-small cell lung cancer ( NSCLC ) who had not received prior chemotherapy . | carboplatin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? FLAIE ( fludarabine , cytarabine , idarubicin , and etoposide ) , a four drug induction chemotherapy for adult acute myeloid leukemia : A single center experience . | fludarabine cytarabine idarubicin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Overall , our study shows that the combination of dabrafenib and cetuximab results in increased antitumor activity and decreased stem cell capacities in BRAF(V600E)-mutant CRC cells . | dabrafenib cetuximab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Forty-seven patients with previously untreated metastatic or unresectable colorectal adenocarcinoma received capecitabine 1000 mg/m2 twice daily on days 2 - 15 and intravenous irinotecan 100 mg/m2 on days 1 and 8 , every 21 days . | capecitabine irinotecan are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Amphotericin B plus flucytosine were initially given to 4 patients , all of them developed liver and renal abnormalities to some degree after therapy . | Amphotericin flucytosine are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Liposomes were surface modified with transferrin ( Tf ) for receptor targeting , and cell penetrating peptide PFVYLI ( PFV ) to increase translocation of doxorubicin ( Dox ) and Erlotinib ( Erlo ) across the BBB into glioblastoma ( U87 ) tumor cells . | doxorubicin Erlotinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Endpoints were determination of maximum tolerated dose of doxorubicin and etoposide , treatment tolerability , and survival . | doxorubicin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Multiple ongoing clinical trials are currently evaluating the role of immune checkpoint inhibitors in ACC ( pembrolizumab , combination pembrolizumab and relacorilant , nivolumab , combination nivolumab and ipilimumab ) . | pembrolizumab relacorilant are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Bevacizumab and intetumumab can be administered safely in combination . | Bevacizumab intetumumab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The protocol consisted of oral gefitinib 250 mg daily for 1 year plus intravenous oxaliplatin 85 or 100 mg/m(2 ) on days 1 , 15 , and 29 , and RT ( 50.4 Gy in 28 1.8-Gy fractions ) . | gefitinib oxaliplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Forty-eight patients were treated with mitoxantrone alone , 40 with mitoxantrone plus beta-interferon , 11 with fluorouracil plus folinic acid and the remaining four with adriamycin . | mitoxantrone beta-interferon are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Fifty-one HIV-negative patients with an average age of 50.3 years were treated with chemotherapy regimen included 2500 mg/m(2 ) MTX with Leucovorin rescue and 1.4 mg/m(2 ) vincristine ( day two ) , which was administered every other week for 6 weeks . | Leucovorin vincristine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors : a Children 's Oncology Group study . | decitabine doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Our study involves a preliminary phase II trial , which evaluates the activity , feasibility and tolerability of a sequential combination of docetaxel and gemcitabine followed by docetaxel and carboplatin , as first-line treatment for inoperable NSCLC . | docetaxel gemcitabine carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The combination of galunisertib and sorafenib showed acceptable safety and a prolonged OS outcome . | galunisertib sorafenib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? All the patients were conditioned with busulfan ( BU ) 12 mg.kg-1 and cyclophosphamide ( CY ) 3.6 g.m-2 , of whom 4 were conditioned with additioned antithymocyte globulin(ATG ) . | busulfan cyclophosphamide antithymocyte globulin(ATG are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Phase II study of an intensive combination chemotherapy with cisplatin , adriamycin , etoposide and cyclophosphamide ( CAVE ) in small cell lung cancer . | cisplatin adriamycin etoposide cyclophosphamide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Simultaneous treatment with gefitinib and pemetrexed enhanced cell growth inhibition and cell death and prevented the appearance of gefitinib resistance mediated by T790 M mutation or epithelial-to-mesenchymal transition ( EMT ) in PC9 and HCC827 cells , respectively . | gefitinib pemetrexed are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Two courses of eight drugs in 1 day followed by two courses of etoposide plus carboplatin ( 500 and 800 mg/m(2 ) per course , respectively ) were administered after surgery . | etoposide carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? 3 . When timolol was administered concomitantly with hydrochlorothiazide , plasma renin activity was suppressed and blood pressure was significantly lowered . | timolol hydrochlorothiazide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Phase I study combining treatment with temsirolimus and sunitinib malate in patients with advanced renal cell carcinoma . | temsirolimus sunitinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? 2 . The two combination treatment regimes lowered the 12 h post-dose blood pressure more effectively than did atenolol alone , but the high dose nifedipine combination was no more effective than the low dose nifedipine combination . | atenolol nifedipine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Low-risk patients received three cycles of modified CODOX-M ( cyclophosphamide , doxorubicin , adriamycin , vincristine with intrathecal methotrexate and cytarabine followed by high-dose systemic methotrexate , regimen A ) . | cyclophosphamide doxorubicin vincristine methotrexate cytarabine adriamycin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Background The National Wilms Tumor Study ( NWTS ) approach to treating stage III favorable-histology Wilms tumor ( FHWT ) is Regimen DD4A ( vincristine , dactinomycin , and doxorubicin ) and radiation therapy . | vincristine doxorubicin dactinomycin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Enrolled patients received ADT in the form of leuprolide every 12 weeks for 24 months with bicalutamide initiating after the completion of chemotherapy . | leuprolide bicalutamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? To evaluate the efficacy and safety of lapatinib ( L ) and trastuzumab ( T ) combination in HER2-positive metastatic breast cancer ( MBC ) patients previously treated with T and/or L. | lapatinib trastuzumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Meloxicam combined with sorafenib synergistically inhibits tumor growth of human hepatocellular carcinoma cells via ER stress-related apoptosis . | Meloxicam sorafenib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? We validated these initial findings in samples collected in a clinical trial comparing the nucleoside analog fludarabine alone or in combination with the alkylating agent cyclophosphamide in untreated CLL samples collected prior to starting therapy ( E2997 ) . | fludarabine cyclophosphamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Cetuximab is a monoclonal antibody against EGFR with additive preclinical activity with irinotecan . | Cetuximab irinotecan are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A non-specific inhibitor of 5-HT reuptake , imipramine , did not produce this amnesic effect , nor did the combination of fenfluramine with the MAOI tranylcypromine , although it produced , as expected , the " serotonergic syndrome . " Results for the metabolic precursor of 5-HT , 5-HTP , also administered peripherally , were inconsistent , with amnesic effects seen at 5 and 20 mg/kg but none at 10 mg/kg . | fenfluramine tranylcypromine are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Activity of irinotecan and temozolomide in the presence of O6-methylguanine-DNA methyltransferase inhibition in neuroblastoma pre-clinical models . | irinotecan temozolomide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This is a phase II study of etoposide , vincristine , and doxorubicin , administered as a 96-hour continuous infusion , with intravenous ( IV ) bolus cyclophosphamide and oral prednisone ( EPOCH ) in 74 consecutive patients who relapsed from or failed to respond to most of the same drugs administered on a bolus schedule . | etoposide vincristine doxorubicin cyclophosphamide prednisone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Based on the FIRM-ACT trial , mitotane plus etoposide , doxorubicin , and cisplatin is now the established first-line cytotoxic therapy . | mitotane etoposide doxorubicin cisplatin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Consistent with previous reports , genistein combined with doxorubicin had a synergistic effect on MCF-7/Adr cells , and genistein reduced the chemoresistance of these cells . | genistein doxorubicin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Combination of ibrutinib and ublituximab ( n = 64 ) had an ORR of 78 % ( CR 7 % ) in a phase 3 study . | ibrutinib ublituximab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Paclitaxel , 5-fluorouracil , hydroxyurea , and concomitant radiation therapy for poor-prognosis head and neck cancer . | Paclitaxel 5-fluorouracil hydroxyurea are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The results suggest that the superior efficacy of nivolumab plus ipilimumab over sunitinib was maintained in intermediate-risk or poor-risk and intention-to-treat patients with extended follow-up , and show the long-term benefits of nivolumab plus ipilimumab in patients with previously untreated advanced renal cell carcinoma across all risk categories . | nivolumab ipilimumab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A randomized trial of mobilization of peripheral blood stem cells with cyclophosphamide , etoposide , and granulocyte colony-stimulating factor with or without cisplatin in patients with malignant lymphoma receiving high-dose chemotherapy . | cyclophosphamide etoposide cisplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Treatment of pancreatic cancer with a combination of docetaxel , gemcitabine and granulocyte colony-stimulating factor : a phase II study of the Greek Cooperative Group for Pancreatic Cancer . | docetaxel gemcitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Such situations are known as exposing to pneumococcal meningitis and to resistance of the strain involved to penicillin G. Both patients were cured by vancomycin in continuous infusion associated with rifampicin or fosfomycin . | vancomycin rifampicin fosfomycin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In 2011 , the combination of rituximab with bendamustine ( 31 % ) was most frequent used followed by the rituximab-fludarabine-cyclophosphamide ( 22 % ) regime . | rituximab bendamustine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The combination of ofatumumab and bendamustine in elderly patients with diffuse large B-cell lymphoma demonstrated modest efficacy compared with standard of care . | ofatumumab bendamustine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The most common chemotherapy and route of administration for systemic treatment is paclitaxel plus carboplatin given intravenously . | paclitaxel carboplatin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Aflibercept has been used in combination with folinic acid (leucovorin)-fluorouracil-irinotecan ( FOLFIRI ) chemotherapy in mCRC patients and among patients with mCRC with wild-type KRAS , the outcomes were significantly improved by panitumumab in combination with folinic acid (leucovorin)-fluorouracil-oxaliplatin ( FOLFOX ) or FOLFIRI . | panitumumab folinic acid are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The current mainstay of systemic treatment for patients with metastatic or unresectable disease remains doxorubicin with or without ifosfamide in the first-line setting . | doxorubicin ifosfamide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? After an initial 6 - 8 weeks of metformin , they received either letrozole ( 2.5 mg ) or clomiphene ( 100 mg ) from day 3 - 7 of their menstrual cycle . | metformin letrozole are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? No study has evaluated the significance of CD30 expression in DLBCL patients treated with rituximab , etoposide , prednisone , vincristine , cyclophosphamide , and doxorubicin ( R-EPOCH ) . | rituximab etoposide prednisone vincristine cyclophosphamide doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Suggested evidence linking the association of the drug to the event includes knowing that Panitumumab and Irinotecan can contribute to all other possible causes of cardiac arrest , temporal relationship and pharmacological time plausibility , and recognized association with the product or the class . | Panitumumab Irinotecan are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Cyclophosphamide , mitoxantrone , fluorouracil versus conventional CMF as adjuvant treatment in node-positive breast cancer patients . | Cyclophosphamide mitoxantrone fluorouracil are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? After the operation , an alternating vincristine , doxorubicin , and cyclophosphamide/ifosfamide and etoposide ( IE ) regimen was given for eight cycles , and the patient survived for 66 mo without progression . | vincristine doxorubicin etoposide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A total of 34 patients with androgen-independent prostate cancer received doxorubicin , 30 mg/m(2 ) , every 2 weeks and ketoconazole daily , 400 mg orally every 8 hours . | doxorubicin ketoconazole are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Three first-line drugs are recommended , pegylated interferon alfa-2a , entecavir and tenofovir . | pegylated interferon alfa-2a entecavir tenofovir are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A phase 1/2 trial of tivozanib in combination with durvalumab is currently underway . | tivozanib durvalumab are the drug combinations. Need more context. |