qtype
stringclasses 1
value | Question
stringlengths 113
599
| Answer
stringlengths 58
185
|
|---|---|---|
drug_combination | What is the drug combination mentioned in the following sentence? In newly diagnosed patients with MCL ineligible for intensive therapy and ASCT , the standard-of-care has generally been R-CHOP ( rituximab , cyclophosphamide , doxorubicin , vincristine , and prednisone ) , followed by rituximab , maintenance . | rituximab cyclophosphamide doxorubicin vincristine prednisone rituximab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The results indicate that BU and IPSA behave additively with verapamil and carbamazepine , which may be due to a common action on the same subtype of calcium channels . | BU IPSA verapamil carbamazepine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The combination of docetaxel and trastuzumab is well tolerated and has clinically meaningful antitumor activity . | docetaxel trastuzumab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Combined treatment using insulin-like growth factor-I with prednisolone or ursodeoxycholic acid additively increased bile flow volume . | insulin-like growth factor-I prednisolone are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Pharmacodynamic modeling of combined chemotherapeutic effects predicts synergistic activity of gemcitabine and trabectedin in pancreatic cancer cells . | gemcitabine trabectedin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Conversely , down-regulation of cyclin E1 gene expression or inhibition of cyclin E1 by the cyclin-dependent kinase ( CDK ) inhibitors dinaciclib ( DIN ) or flavopiridol sensitized HCC cells to regorafenib and sorafenib by inducing apoptosis . | flavopiridol regorafenib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Cytarabine and etoposide intensification exceeded the acceptable toxic death rate of 10 % . | Cytarabine etoposide are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? After initiating warfarin plus lenvatinib , INR assays are necessary . | warfarin lenvatinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Merimepodib ( MMPD ) is an orally administered , inosine monophosphate dehydrogenase inhibitor that has shown antiviral activity in nonresponders with chronic hepatitis C ( CHC ) when combined with pegylated interferon alfa 2a ( Peg-IFN-alfa-2a ) and ribavirin ( RBV ) . | interferon alfa ribavirin Merimepodib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? [ Effects of endostatin and doxycycline on microcirculation patterns in melanoma and their relevant molecular mechanisms ] . | endostatin doxycycline are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Subsequent investigation of therapeutic responsiveness upon treatment with the current systemic gold standard EDP-M ( etoposide , doxorubicin , cisplatin and mitotane ) demonstrated maintenance of the clinically observed drug resistance for MUC-1 exclusively . | etoposide doxorubicin cisplatin mitotane are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Oxaliplatin is active in NSCLC , offers advantage in terms of toxicity , and shows synergism with gemcitabine . | Oxaliplatin gemcitabine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Doxorubicin and lapatinib combination nanomedicine for treating resistant breast cancer . | Doxorubicin lapatinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The HIV protease inhibitor ritonavir , a strong CYP3A4 inhibitor , decreased first-pass metabolism of orally administered docetaxel . | ritonavir docetaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Ramucirumab plus osimertinib demonstrated encouraging safety and antitumor activity in T790M-positive EGFR-mutant NSCLC . | Ramucirumab osimertinib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The patient was complicated with hemophagocytic lymphohistiocytosis ( HLH ) and invasive aspergillosis ( IPA ) after re-induction treatment with FLAG-IDA following etoposide , cytarabine , and mitoxantrone . | etoposide cytarabine mitoxantrone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Pretreatment of the rats with methamphetamine ( MAP ) for 8 days prior to chronic haloperidol significantly enhanced the DOPAC and HVA increase produced by the challenge with haloperidol in both brain areas . | methamphetamine haloperidol are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The quantity and composition of bacterial communities were altered by treatment with the five-antibiotic cocktail and by treatment with vancomycin and ampicillin . | vancomycin ampicillin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Successful treatment of an elderly Langerhans cell sarcoma patient by EPOCH ( etoposide , prednisone , vincristine , cyclophosphamide , and doxorubicin ) chemotherapy . | etoposide prednisone vincristine cyclophosphamide doxorubicin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Tremelimumab plus gemcitabine demonstrated a safety and tolerability profile , warranting further study in patients with metastatic pancreatic cancer . | Tremelimumab gemcitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Longer progression-free survival ( PFS ) and overall survival ( OS ) were observed with T-DM1 compared with capecitabine plus lapatinib in all biomarker subgroups . | capecitabine lapatinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Pharmacokinetics , Safety , and Antitumor Effect of Apalutamide with Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer : Phase Ib Study . | Apalutamide Abiraterone Prednisone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Combined treatment with nintedanib ( 200 mg/bid ) plus letrozole ( 2.5 mg/day ) effectively suppressed FGFR1 and aromatase activity , and these respective doses can be used as starting doses in any subsequent trials . | nintedanib letrozole are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A significant response to a combination of trastuzumab and vinorelbine in HER2-negative metastatic breast cancer with HER2 V777L mutation . | trastuzumab vinorelbine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients ( n = 28 ) with metastatic solid tumors were randomized to receive pretreatment with Dex or GM-CSF or no pretreatment prior to courses 1 or 2 of carboplatin and ifosfamide . | carboplatin ifosfamide Dex are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? After a thyroidectomy , she was treated with intravenous methylprednisolone pulse therapy and oral prednisolone followed by tacrolimus therapy . | methylprednisolone prednisolone tacrolimus are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The vinca alkaloid , vinorelbine , and the multi-targeted antifol , pemetrexed , were additive with imexon in both cell lines . | vinorelbine pemetrexed imexon are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Supine blood pressures ( group means ) were 171/97 ( placebo ) , 147/85 ( enalapril ) , 154/84 ( atenolol ) and 144/78 ( enalapril plus atenolol ) ( S.E.M. + /- 2/+/- 1-ANOVA ) , and standing blood pressures were 170/105 ( placebo ) , 146/92 ( enalapril ) , 154/92 ( atenolol ) and 147/86 ( enalapril plus atenolol ) ( S.E.M. + /- 3/+/- 1 ) . | enalapril atenolol are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? To evaluate the toxicity and activity of infusional fluorouracil ( FU ) , folinic acid ( FA ) , and oxaliplatin , administered every 2 weeks in patients with metastatic gastric cancer . | fluorouracil folinic acid oxaliplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Bevacizumab in combination with interferon alfa is now approved for treatment-naïve advanced renal cell carcinoma ( RCC ) in both the US and Europe . | Bevacizumab interferon alfa are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? YM155 in combination with rituximab was tolerable with encouraging antitumor activity and durable responses in relapsed aggressive B-cell NHL patients . | YM155 rituximab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Similarly , a significant benefit in progression-free survival for carboplatin plus gemcitabine versus carboplatin monotherapy was seen in the Gynecologic Cancer InterGroup trial . | carboplatin gemcitabine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? We report a case series of 10 patients that were treated with betamethasone valerate foam ( 0.12 % ) in the morning and topical tazarotene cream ( 0.1 % ) in the evening for a total of 12 weeks or until plaques cleared . | betamethasone tazarotene are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Valsartan and sulfasalazine also reduced markers of oxidative stress after DSS administration . | Valsartan sulfasalazine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Metronomic 5-fluorouracil , oxaliplatin and irinotecan in colorectal cancer . | 5-fluorouracil oxaliplatin irinotecan are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Combination of mefloquine and praziquantel gave better curative effects than praziquantel or mefloquine given alone . | mefloquine praziquantel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The aim of this study was to evaluate whether trastuzumab modifies the pharmacokinetics of epirubicin and its metabolites . | trastuzumab epirubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central Cancer Treatment Group N9831 adjuvant breast cancer trial . | doxorubicin cyclophosphamide paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Bupropion differentially alters the aversive , locomotor and rewarding properties of nicotine in CD-1 mice . | Bupropion nicotine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The first trial was a multicenter randomized phase III study of chemotherapy ( doxorubicin/cyclophosphamide or paclitaxel ) + /- trastuzumab , and the second was a multicenter phase II trial of vinorelbine + trastuzumab . | doxorubicin/cyclophosphamide trastuzumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Peginterferon alfa-2a ( 40KD ) plus ribavirin has given an overall sustained virological response of 18 % in F3/F4 previous nonresponder US patients . | Peginterferon alfa-2a ribavirin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? We conducted a phase I and pharmacokinetic study with the erlotinib and celecoxib combination in patients with advanced premalignant lesions . | erlotinib celecoxib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? [ Efficacy of combination therapy of lamivudine and adefovir dipivoxyl for patients with hepatitis B-induced decompensated liver cirrhosis ] . | lamivudine adefovir are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The effervescent aspirin preparation is at least as effective as the combination of aspirin plus metoclopramide , but has fewer side effects . | aspirin metoclopramide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This is an investigator-initiated , multicenter randomized controlled trial ( RCT ) designed to compare the combination treatment of adalimumab and methotrexate with adalimumab monotherapy in patients with psoriasis . | adalimumab methotrexate are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? These results provide compelling preclinical rationale indicating lapatinib to be a potentially efficacious chemotherapeutic combination partner for irinotecan in the treatment of gastrointestinal carcinomas . | lapatinib irinotecan are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Women with previously untreated bulky ( primary tumor > /= 4 cm ) stage IB or IIA non-small-cell carcinoma of the uterine cervix were randomly assigned to receive either cisplatin 50 mg/m(2 ) and vincristine 1 mg/m(2 ) for 1 day and bleomycin 25 mg/m(2 ) for 3 days for three cycles followed by radical hysterectomy ( NAC arm ) or receive primary pelvic radiotherapy only ( R/T arm ) . | cisplatin vincristine bleomycin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The purpose of this study was to evaluate the efficacy of long-term use of bupropion sustained release ( SR ) , the nicotine patch , and the combination of these 2 treatments in patients who initially failed treatment . | bupropion nicotine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Systemic chemotherapy with vincristine , actinomycin D , plus cyclophosphamide ( VAC therapy ) , and etoposide plus cisplatin ( EP therapy ) were made according to Intergroup Rhabdomyosarcoma Study (IRS)-IV Regimen 45 . | vincristine actinomycin D cyclophosphamide etoposide cisplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? He was asymptomatic half a year after the rituximab with cyclophosphamide , vincristine , doxorubicin , methotrexate/ifosfamide , etoposide , and high-dose cytarabine protocol therapy ; the lymphoma is in remission . | rituximab cyclophosphamide vincristine doxorubicin methotrexate/ifosfamide etoposide cytarabine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? To evaluate empiric nifuratel , amoxicillin , and bismuth triple therapy for H. pylori gastritis in childhood . | nifuratel amoxicillin bismuth are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The patient was treated in July 1998 with anthracycline , etoposide , and behenoyl cytarabine chemotherapy for AML ( French-American-British classification , M2 ; World Health Organization classification , AML with maturation ) and achieved complete remission . | anthracycline etoposide behenoyl cytarabine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The risk increased when ASA was combined with clopidogrel , compared with aspirin alone ( OR , 1.86 ; 95 % CI , 1.49 - 2.31 ) , anticoagulants vs low doses of ASA alone ( OR , 1.93 ; 95 % CI , 1.42 - 2.61 ) , or in studies that included patients with a history of GI bleeding or of longer duration . | clopidogrel ASA are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Raloxifene , an anti-osteoporotic drug , is recently approved for prevention of breast cancer in postmenopausal women and thus the drug may be employed to combat the bony adverse effects of letrozole , another anticancer drug . | Raloxifene letrozole are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In a previous trial , we found that adding the antiandrogen flutamide to leuprolide acetate ( a synthetic gonadotropin-releasing hormone that results in medical ablation of testicular function ) significantly improved survival as compared with that achieved with placebo plus leuprolide acetate . | flutamide leuprolide acetate are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Contraceptives containing desogestrel or levonorgestrel have different effects on serum lipoproteins and post-heparin plasma lipase activities . | desogestrel levonorgestrel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Concentrations of guaifenesin , diphenhydramine , and chlorpheniramine detected in the heart blood were 27.4 , 8.8 , and 0.2 mg/L , respectively . | guaifenesin diphenhydramine chlorpheniramine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The standard chemotherapy for localized ESFT now comprises vincristine , actinomycin D , cyclophosphamide and doxorubicin ( VACD ) in Europe or vincristine , doxorubicin , cyclophosphamide , ifosfamide and etoposide ( VDC-IE ) in North America . | vincristine actinomycin D cyclophosphamide doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Ceftriaxone plus gentamicin or ceftriaxone alone for streptococcal endocarditis in Japanese patients as alternative first-line therapies . | Ceftriaxone gentamicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Combined therapy : what does acamprosate and naltrexone combination tell us ? | acamprosate naltrexone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Reflecting the role of STAT3 in inducing localized immune suppression , using both atovaquone and pyrimethamine resulted in the modulation of immunoregulatory genes predicted to enhance an immune response , including upregulation of ICOSLG ( Inducible T-Cell Costimulator Ligand or B7H2 ) . | atovaquone pyrimethamine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? TVR can be used in combination with tenofovir , emtricitabine and raltegravir for patients with hemophilia . | tenofovir emtricitabine raltegravir TVR are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Topical therapy with azithromycin and oral therapy with doxycycline relieved signs and symptoms and restored the lipid properties of the meibomian gland secretion toward normal . | azithromycin doxycycline are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Drug combinations , especially rapamycin + doxycycline may have promising anti-tumour effect in gliomas . | rapamycin doxycycline are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Treatment with PUVA ( psoralen-ultraviolet-A ) combined with 40 - -80 mg prednisolone and then with chemotherapy [ COPP regimen ( cyclophosphamide , vincristine , procarbacine , prednisone ) , high-dosage methotrexate followed by citrovorum factor rescue ] was not successful . | prednisolone cyclophosphamide vincristine prednisone methotrexate psoralen-ultraviolet-A procarbacine citrovorum are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? We evaluated a sequential treatment with Vinorelbine followed by Gemcitabine to determine its effect on survival and the toxicity in this patient population . | Vinorelbine Gemcitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Apoptosis in Hep2 cells treated with etoposide and colchicine . | etoposide colchicine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The objective of this phase II study was to evaluate the efficacy and toxicity of carboplatin and weekly paclitaxel combination chemotherapy in previously untreated , advanced non-small cell lung cancer ( NSCLC ) . | carboplatin paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Therapy consisted of seven cycles of VCAP ( vincristine , cyclophosphamide , doxorubicin and prednisone ) , AMP ( doxorubicin , ranimustine and prednisone ) and VECP ( vindesine , etoposide , carboplatin and prednisone ) . | vincristine cyclophosphamide doxorubicin prednisone doxorubicin ranimustine prednisone etoposide carboplatin prednisone vindesine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In HER2-amplified cells , the combination of trastuzumab and lapatinib was evaluated using the median effects principal . | trastuzumab lapatinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Sorafenib monotherapy and combinations with taxanes , bevacizumab and ixabepilone showed inadequate efficacy , while efficacy results from combinations with gemcitabine and/or capecitabine and possibly tamoxifen were more promising . | Sorafenib gemcitabine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? This article reviews the pertinent studies regarding paclitaxel combined with cisplatin or carboplatin , discusses the remaining controversies surrounding how best to combine these agents , and provides opinions regarding the discordant outcomes noted in studies of the paclitaxel-platinum doublet . | paclitaxel cisplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Hyperthermia could increase the sensitivity of SKOV3 to cis-platinum , carboplatin and oxaliplatin ( P < 0.05 ) . | cis-platinum Hyperthermia are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A prospective phase 2 trial of short-course ( SC ) radiation therapy ( RT ) with 25 Gy over 5 fractions , followed by 4 cycles of 5-fluorouracil , oxaliplatin , and leucovorin ( mFOLFOX6 ) before surgery was recently completed at our institution . | 5-fluorouracil oxaliplatin leucovorin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? [ A case of advanced gastric cancer successfully treated with trastuzumab , capecitabine , and Cisplatin therapy followed by curative resection ] . | trastuzumab capecitabine Cisplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Sulpiride plus hydroxyzine decrease tinnitus perception . | Sulpiride hydroxyzine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? We gave 2 , 3 , 5 and 5 mg/day/body of recombinant tissue plasminogen activator ( tPA ) followed by heparin and prostaglandin E1 ( PGE1 ) effectively and without significant side effect on days 9 , 10 , 13 and 14 , respectively . | tissue plasminogen activator heparin prostaglandin E1 are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Roxithromycin and clarithromycin , 14-membered ring macrolides , potentiate the antitumor activity of cytotoxic agents against mouse B16 melanoma cells . | Roxithromycin clarithromycin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The EVA regimen ( etoposide , vinblastine , doxorubicin ) is an attempt to substitute a known active agent , etoposide , for bleomycin and dacarbazine . | etoposide vinblastine doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Carvedilol and imatinib mesylate alone reduced cell number , BrDU-LI , cAMP levels and spheroid volume . | Carvedilol imatinib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The recommended phase II dose ( RP2D ) was cytarabine 10 mg bid days 1 - 10 and sorafenib 600 mg/day days 2 - 28 . | cytarabine sorafenib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We performed a single-arm phase II trial of panitumumab in patients with KRAS wild-type metastatic colorectal cancer that had progressed on prior cetuximab . | panitumumab cetuximab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Two Phase 1 studies assessed effects of ABT-450 ( 150 mg coadministered with ritonavir 100 mg once daily ) , ombitasvir ( 25 mg once daily ) , and dasabuvir ( 400 mg twice daily ) on the pharmacokinetics , safety , and tolerability of a single dose of cyclosporine ( 30 mg ) or tacrolimus ( 2 mg ) in healthy volunteers ( N = 12 per study ) . | ABT-450 ritonavir ombitasvir dasabuvir cyclosporine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Antiplatelet therapy with dipyridamole , 100 mg q.i.d . , starting 2 days before surgery , followed by aspirin , 325 mg t.i.d . plus dipyridamole , 75 mg t.i.d . , 7 hours after surgery was assessed in the prevention of saphenous vein bypass graft occlusion . | dipyridamole aspirin dipyridamole are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Toxicity patterns following stepwise combinations of cyclophosphamide , methotrexate and fluorouracil . | cyclophosphamide methotrexate fluorouracil are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? All patients were treated with the combination of lapatinib ( 1250 mg/day , continuously ) and capecitabine ( 2000 mg/m(2 ) on days 1 through 14 of a 21-day cycle ) . | lapatinib capecitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Effect of curcumin , a natural phytochemical in restoring doxorubicin sensitivity by targeting Aurora A was assessed furthermore . | curcumin doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Our goals were to : establish the maximum-tolerated dose of olaparib tablets combined with metronomic carboplatin and paclitaxel in patients with relapsed high-grade serous ovarian cancer ; evaluate dose-limiting toxicities ; and evaluate efficacy at the maximum tolerated dose . | olaparib carboplatin paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? All patients in this study were treated with decitabine of 15 mg/m2 for 5 days and G-CSF for priming , in combination with cytarabine of 10-mg/m2 q12h for 7 days and aclarubicin of 10 mg/day for 4 days ( D-CAG ) . | decitabine cytarabine aclarubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Pertuzumab is the most recent agent approved by the US Food and Drug Administration in combination with trastuzumab and docetaxel for the treatment of patients with HER2(+ ) metastatic breast cancer who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease . | Pertuzumab trastuzumab docetaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Safety and efficacy of sorafenib followed by regorafenib or lenvatinib in patients with hepatocellular carcinoma . | sorafenib regorafenib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The combination of boceprevir or telaprevir with peginterferon-alfa and ribavirin for the treatment of patients infected with HCV genotype 1 has led to significantly increased rates of sustained virological response ( SVR ) in phase III trials . | boceprevir peginterferon-alfa ribavirin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In contrast , the combination of plumbagin with AR antagonists , such as bicalutamide and enzalutamide , showed no improvement over AR antagonists alone . | bicalutamide plumbagin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The B-cell lymphoma 2 ( BCL-2 ) inhibitor venetoclax has an emerging role in acute myeloid leukemia ( AML ) , with promising response rates in combination with hypomethylating agents or low-dose cytarabine in older patients . | venetoclax cytarabine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Combination chemotherapy with vincristine , bleomycin , and methotrexate for advanced head and neck cancers . | vincristine bleomycin methotrexate are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Combination therapy with labetalol ( 400 mg/day ) and prazosin ( 6 mg/day ) was unsatisfactory , and the addition of long-acting nifedipine ( 40 mg/day ) produced a marked decrease in blood pressure . | labetalol prazosin are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? It was identified as C. lunata ( Wakker ) Boedijn var . aeria ( Batista , Lima and Vasconcelos ) Ellis ( IMI 253204 ) and its growth was better at 28 degrees C than at 37 degrees C. In vitro , the fungus was most sensitive to amphotericin B followed by miconazole nitrate , clotrimazole and triphenyltin isoselenocyanate 4-picoline which had the same activity . | amphotericin miconazole clotrimazole triphenyltin isoselenocyanate 4-picoline are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Conclusions Everolimus plus mFOLFOX-6 + bevacizumab is tolerable and demonstrated preliminary efficacy for first-line mCRC . | Everolimus bevacizumab mFOLFOX-6 are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? We conducted a prospective phase II study to determine the response rate , toxicity , and survival rate of concurrent weekly paclitaxel , carboplatin , and hyperfractionated radiation therapy ( paclitaxel/carboplatin/HFX RT ) followed by 2 cycles of paclitaxel and carboplatin for locally advanced unresectable non-small cell lung cancer ( NSCLC ) . | paclitaxel carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A phase Ib study of pertuzumab , a recombinant humanised antibody to HER2 , and docetaxel in patients with advanced solid tumours . | pertuzumab docetaxel are the drug combinations. Need more context. |