qtype
stringclasses 1
value | Question
stringlengths 113
599
| Answer
stringlengths 58
185
|
|---|---|---|
drug_combination | What is the drug combination mentioned in the following sentence? Health-related quality of life of patients with advanced breast cancer treated with everolimus plus exemestane versus placebo plus exemestane in the phase 3 , randomized , controlled , BOLERO-2 trial . | everolimus exemestane are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Phase 2 study of irinotecan and paclitaxel in patients with recurrent or refractory small cell lung cancer . | irinotecan paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This was a multicenter phase II pilot study of rituximab and modified hyper-fractionated cyclophosphamide , vincristine doxorubicin , dexamethasone ( modified R-hyperCVAD ) administered every 28 days for four to six cycles followed by rituximab maintenance therapy consisting of four weekly doses every 6 months for 2 years . | rituximab cyclophosphamide vincristine doxorubicin dexamethasone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This trial will close to accrual in September 1995 , and analysis of the trial should provide useful information regarding the potential synergy of doxorubicin and paclitaxel , the degree of cross-resistance between the two compounds , and the relationship between steady-state paclitaxel levels and response to therapy . | doxorubicin paclitaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? 26 patients received adjuvant chemotherapy ( carboplatin plus etoposide ) . | carboplatin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A concentration-dependent effect of venetoclax on PFS and a prolonged synergistic effect of 6 cycles of concomitant rituximab were identified . | venetoclax rituximab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Carboplatin plus taxanes are non-inferior to epirubicin plus cyclophosphamide followed by taxanes as adjuvant chemotherapy for early triple-negative breast cancer . | Carboplatin taxanes are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Comparative study of ceftriaxone monotherapy versus a combination regimen of cefuroxime plus gentamicin for treatment of serious bacterial infections : the efficacy , safety and effect on fecal flora . | cefuroxime gentamicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A phase 1b , dose escalation study was performed to assess maximum tolerated dose , safety/toxicity , clinical efficacy and explored pharmacodynamic biomarkers of response to entinostat combined with lapatinib with or without trastuzumab . | entinostat lapatinib trastuzumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Objective and palliative effect of chemotherapy is marked for weekly doxorubicin , prednisone with mitoxantrone and etoposide associated with platin-salts for prostatic carcinoma with neuroendocrine differentiation . | doxorubicin prednisone mitoxantrone etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The recommendations derived from the comprehensive assessment of the literature and guidelines are to continue NSAIDs and low dose aspirin , and phosphodiesterase inhibitors ( dipyridamole , cilostazol , Aggrenox ) during interventional techniques . | aspirin dipyridamole are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Enhanced growth-inhibiting effects were also observed in HCC cells treated with a combination of sorafenib and silibinin . | sorafenib silibinin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The effects of the Acanthopanax obovatus polysaccharide ( AOPS ) as well as its combination with cyclophosphamide ( CY ) or prednisolone on immune responses were investigated in mice . | Acanthopanax obovatus polysaccharide cyclophosphamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We did the QuiRedex study to compare early treatment with lenalidomide plus dexamethasone with observation in patients with high-risk smouldering multiple myeloma . | lenalidomide dexamethasone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Of the patients , 26 were treated with a chemotherapy regimen known to cause prolonged and sometimes permanent azoospermia ( BEACOPP -- bleomycin , etoposide , doxorubicin , cyclophosphamide , vincristine , procarbazine , and prednisolone ) and 26 with a regimen known to have a much milder effect on gonadal function ( ABVD -- doxorubicin , bleomycin , vincristine , and dacarbazine ) . | doxorubicin bleomycin vincristine dacarbazine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Tissue from preclinical models and patients ' biopsies were collected pre-treatment and on Cycle ( C ) 1 , Day ( D ) 9 to characterize the effect of gemcitabine and salirasib on activated Ras protein levels . | gemcitabine salirasib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The effect of dasatinib , an inhibitor of Src and Abl kinases , on paclitaxel sensitivity was measured in ovarian cancer cells and HEY xenografts . | dasatinib paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The maximum tolerated dose ( MTD ) was 20 mg/m2/day I.V. bolus for 5 days of fludarabine plus 60 mg/m2/day I.V. of paclitaxel given as a continuous infusion over 72 hours . | fludarabine paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Further studies are needed to identify predictors of response and toxicity to this approach , as well as the optimal scheduling of ipilimumab with maintenance nivolumab . | ipilimumab nivolumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Efficacy of palonosetron plus aprepitant in preventing chemoradiotherapy-induced nausea and emesis in patients receiving daily low-dose cisplatin-based concurrent chemoradiotherapy for uterine cervical cancer : a phase II study . | palonosetron aprepitant are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Pre/peri/postmenopausal women with HR+/HER2- MBC were randomized 2:1 to fulvestrant ( 500 mg ) and either palbociclib ( 125 mg/day ; 3 weeks on/1 week off ; n = 347 ) or placebo ( n = 174 ) . Prespecified exploratory analyses compared the efficacy ( data cutoff : October 23 , 2015 ) , safety , and pharmacokinetics ( data cutoff : December 5 , 2014 ) in Japanese women versus the overall population . | fulvestrant palbociclib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? was lowest in the propofol + dexmedetomidine group ( all , P < 0.05 ) , and the AUC of pulse oximetry was significantly higher in the propofol + dexmedetomidine and propofol + ketamine groups compared to the other 2 groups ( both , P < 0.05 ) . | propofol ketamine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients aged 15 to 60 years , presenting with newly diagnosed acute myeloid leukemia ( AML ) were randomized to receive either high-dose cytarabine , 3 g/m2 12 hourly on days 1 , 3 , 5 , and 7 for 8 doses , daunorubicin 50 mg/m2 days 1 to 3 , etoposide 75 mg/m2 days 1 to 7 , ( HIDAC-3 - 7 ) or standard dose cytarabine 100 mg/m2 continuous intravenous infusion for 7 days with daunorubicin and etoposide at the same dose and schedule as above ( 7 - 3 - 7 ) . | cytarabine daunorubicin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Therefore , if a combination regimen is necessary to control CMV in a patient , foscarnet and ganciclovir should be used first . | foscarnet ganciclovir are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A Phase Ib/II Study of Afatinib in Combination with Nimotuzumab in Non-Small Cell Lung Cancer Patients with Acquired Resistance to Gefitinib or Erlotinib . | Afatinib Nimotuzumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? RESULTS In first-line treatment , compared with sunitinib , improvement of one-year CPFS for the nivolumab plus ipilimumab group after living for 0.5 and 0.75 years were 14 % ( from 53.0 % to 67.0 % ) and 16 % ( from 57.0 % to 73.0 % ) higher than the one-year PFS of 6.5 % ( from 42.9 % to 49.4 % ) , with similar results for one-year COS following first-line treatment . | nivolumab ipilimumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This study analysed 126 patients with relapsed , advanced stage follicular lymphoma who received BEAM ( BCNU [ carmustine ] , cytarabine , etoposide , melphalan)-alemtuzumab allogeneic HSCT ( BEAM-allo ) ( n = 44 ) or BEAM-autologous HSCT ( BEAM-auto ) ( n = 82 ) . | carmustine cytarabine etoposide melphalan)-alemtuzumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Apixaban and rivaroxaban were evaluated in phase III trials for prevention of recurrent ischaemia in ACS patients , most of whom were also receiving dual antiplatelet therapy with aspirin and clopidogrel . | aspirin clopidogrel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Furthermore , VPA significantly increased chemosensitivity to fludarabine , flavopiridol , bortezomib , thalidomide and lenalidomide . | VPA fludarabine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Use of the tumor-infiltrating CD8 to FOXP3 lymphocyte ratio in predicting treatment responses to combination therapy with pertuzumab , trastuzumab , and docetaxel for advanced HER2-positive breast cancer . | pertuzumab trastuzumab docetaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The clinical symptoms were relieved after combination of doxycycline , rifampicin , levofloxacin and amikacin for 6 weeks , only one patient with bone destruction needed orthopedic surgery . | doxycycline rifampicin levofloxacin amikacin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Four years after surgery , she experienced a recurrence of breast cancer in the thoracic wall , and was treated with exemestane , toremifene , and fulvestrant for 1 year and 5 months . | exemestane toremifene fulvestrant are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Long-term efficacy of doxazosin plus atenolol in the management of severe and sustained arterial hypertension and reversibility of the cardiac damage induced by chronic cathecolamine excess . | doxazosin atenolol are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? To evaluate the use of low-molecular-weight heparin ( LMWH ) in combination with low-dose aspirin ( LDA ) for the treatment of antiphospholipid antibody (APA)-associated recurrent pregnancy loss and to compare the results with the use of unfractionated heparin ( UFH ) plus LDA . | low-molecular-weight heparin aspirin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Therefore , the pain scores were significantly higher in the neostigmine group than the other two groups ( p = 0.02 ) , but no significant difference was found between the two groups that received dexmedetomidine and a combination of dexmedetomidine + neostigmine . | dexmedetomidine neostigmine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? [ Two cases of complete response to combination chemotherapy of gemcitabine and docetaxel for recurrent ovarian cancer ] . | gemcitabine docetaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Hormonal changes in postmenopausal women with breast cancer treated with trilostane and dexamethasone . | trilostane dexamethasone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? After surgical insertion of a catheter in the hepatic artery , patients were treated with oxaliplatin 100 mg/m(2 ) HAI combined with FU + leucovorin IV according to the LV5FU2 protocol . | oxaliplatin leucovorin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Then , doxorubicin with or without flavopiridol was injected . | doxorubicin flavopiridol are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Subjects were treated in two cycles , 3 months apart , in which they received bicalutamide 150 mg daily days 1 - 28 and tremelimumab on day 29 . | bicalutamide tremelimumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This study examines a novel regimen utilizing the combination of epidurally infused ropivacaine - hydromorphone and scheduled ketorolac . | ropivacaine hydromorphone ketorolac are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients in the HXP arm also received trastuzumab ( 8 mg/kg intravenous infusion on Day 1 ) , concurrently with capecitabine . | trastuzumab capecitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Among targeted therapies , lapatinib has activity in systemic treatment of BM particularly when used in combination with capecitabine . | lapatinib capecitabine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? An in vitro assessment of azithromycin in combination with gentamicin demonstrated inhibition of growth and suggests that clinical trials may be warranted to assess the utility of this combination in treating gonorrhea infections . | azithromycin gentamicin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Clinical efficacy of immunochemotherapy with rituximab , fludarabine and mitoxantrone followed by 2-monthly rituximab maintenance was evaluated in 29 patients with previously untreated follicular lymphoma in a prospective phase II trial ( AGMT-NHL9 ) . | rituximab fludarabine mitoxantrone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Palliative chemotherapy with carboplatin and etoposide produced a minimal response . | carboplatin etoposide are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? In vitro susceptibilities of ocular Bacillus cereus isolates to clindamycin , gentamicin , and vancomycin alone or in combination . | clindamycin gentamicin vancomycin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Most ( ≥ 75 % ) patients received ESHAP ( etoposide , methylprednisolone , cytarabine , cisplatin ) or DHAP ( cisplatin , cytosine arabinoside , dexamethasone ) as salvage chemotherapy . | etoposide methylprednisolone cytarabine cisplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients treated on CCG-3881 ( n = 116 ) received four-drug chemotherapy for 9 months ( cisplatin , cyclophosphamide , doxorubicin , and etoposide ) , with surgery and local radiation to residual disease . | cisplatin cyclophosphamide doxorubicin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? These data suggest that weekly docetaxel plus carboplatin may be an important therapeutic second-line treatment option for patients with DRPC . | docetaxel carboplatin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The recommended phase II dose is bortezomib 1.0 mg/m on days 1 , 4 , 8 , and 11 plus docetaxel 75 mg/m on day 1 , cycled every 21 days . | bortezomib docetaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Budesonide/formoterol pMDI affords equivalent formoterol-related bronchodilatory effects versus formoterol DPI at formoterol doses of 4.5 , 9 , and 18 microg , indicating that practitioners can expect and patients will experience similar bronchodilation from the same dose of formoterol whether it is delivered as monotherapy via a DPI or as combination therapy with budesonide via one pMDI . | formoterol budesonide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A 29-year-old white man with recurrent Hodgkin 's disease received doxorubicin , bleomycin , vinblastine , and dacarbazine ( ABVD ) chemotherapy once every two weeks for 12 cycles . | doxorubicin bleomycin vinblastine dacarbazine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This review focuses on the activity and toxicity of the time-limited combination of venetoclax plus rituximab for the treatment of relapsed or refractory CLL , presenting clinical trial results and data from correlative studies , with the aim of highlighting the strengths of this treatment approach and discuss weaknesses and possible areas of improvement . | venetoclax rituximab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Advanced male breast cancer treatment with the LH-RH analogue buserelin alone or in combination with the antiandrogen flutamide . | buserelin flutamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In an effort to improve its efficacy , mitoxantrone was tested for synergistic activity with cidofovir . | mitoxantrone cidofovir are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In the current study , we investigated the hypothesis that targeting of P-gp by diltiazem can enhance the cytotoxicity of gemcitabine and 5-FU against human pancreatic cancer cells . | diltiazem gemcitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In all , 171 patients with histologically verified non-small cell lung carcinoma were treated with ifosfamide 2.0 g/m2 on days 1 - 5 in combination with ( 91 patients ) etoposide 120 mg/m2 on day 1 . | ifosfamide etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In the large-scale trials carried out in Tanganyika and described in this paper , such a combination , containing amodiaquine for schizontocidal effect and primaquine as a gametocytocide , was administered to three distinct population groups of more than 5000 at differing intervals of time , in order to determine the ability of this combination to interfere with transmission in the absence of other malaria control measures . | amodiaquine primaquine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In transplant eligible patients , induction therapy consists of bortezomib , lenalidomide , dexamethasone ( VRd ) given for approximately 3 - 4 cycles followed by autologous stem cell transplantation ( ASCT ) . | bortezomib lenalidomide dexamethasone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Genistein combined polysaccharide enhances activity of docetaxel , bicalutamide and Src kinase inhibition in androgen-dependent and independent prostate cancer cell lines . | Genistein docetaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Combination therapy with bosentan and sildenafil was effective for this case of refractory PAH associated with fibrotic lung in systemic sclerosis . | bosentan sildenafil are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Analysis of 52 eyes with high-risk retinoblastoma managed with postenucleation adjuvant chemotherapy using vincristine sulfate , etoposide phosphate , and carboplatin showed no evidence of systemic metastasis in any case during a mean ( range ) follow-up of 66 ( 12 - 202 ) months . | vincristine etoposide carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Clinical and cost-effectiveness of capecitabine and tegafur with uracil for the treatment of metastatic colorectal cancer : systematic review and economic evaluation . | capecitabine tegafur are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Cost-effectiveness of cetuximab , cetuximab plus irinotecan , and panitumumab for third and further lines of treatment for KRAS wild-type patients with metastatic colorectal cancer . | cetuximab irinotecan are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This multicenter pilot study assessed the feasibility and efficacy of a time-intensified bleomycin , etoposide , doxorubicin , cyclophosphamide , vincristine , procarbazine , and prednisone ( BEACOPP ) regimen given in 14-day intervals ( BEACOPP-14 ) with granulocyte colony-stimulating factor ( G-CSF ) support in advanced Hodgkin 's lymphoma . | bleomycin etoposide doxorubicin cyclophosphamide vincristine procarbazine prednisone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Safety and efficacy of daclatasvir and asunaprevir in hepatitis C virus-infected patients with renal impairment . | daclatasvir asunaprevir are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We report the results of replacement of steroids by azathioprine ( AZA ) in 25 primary cadaveric renal transplant recipients initially treated with CsA and methylprednisolone ( MP ) . | azathioprine CsA are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? One group of patients was treated with oral mefloquine ( 750 mg ) and artemether ( 600 mg by injection , 200 mg initially and 100 mg every 12 h ) . | mefloquine artemether are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The role of irinotecan and oxaliplatin in the treatment of advanced colorectal cancer . | irinotecan oxaliplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In both cases , chemotherapy comprising rituximab + dose-adjusted EPOCH regimen ( etoposide , prednisone , vincristine , cyclophosphamide and doxorubicin ) was administered . | rituximab etoposide prednisone vincristine cyclophosphamide doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Bleeding prophylaxis included combinations of plasma-derived factor ( VWD ) or recombinant factor ( haemophilia A and haemophilia B ) , desmopressin and/or tranexamic acid . | desmopressin tranexamic are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Although progression-free survival with the bevacizumab plus capecitabine combination is inferior to that noted with bevacizumab plus paclitaxel , we suggest that physicians should consider possible predictive risk factors for overall survival , individual 's treatment priorities , and the differing safety profiles . | bevacizumab capecitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The combination of ixabepilone and bevacizumab was well tolerated , with modest activity in second - or later-line mRCC , but it is not recommended as a therapy without further clinical development . | ixabepilone bevacizumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Eligible patients with unresectable MPM , without disease progression following 4 to 6 cycles of pemetrexed and platinum were randomized 1:1 to observation or continuation of pemetrexed until progression , stratified by number of cycles ( < 6 or 6 ) , cis- or carboplatin containing regimen , and histology . | pemetrexed platinum are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A Phase II trial reported a median OS duration of 8.6 months for patients receiving cetuximab plus irinotecan , plus a median time to progression of 4.1 months , a tumour response rate of 22.9 % and suggested that treatment with cetuximab in combination with irinotecan is associated with significantly more adverse events ( any grade 3 or grade 4 adverse event ) than cetuximab monotherapy . | cetuximab irinotecan are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Our results show meaningful activity of T-DM1 after front-line pertuzumab plus trastuzumab and a taxane , with about 27 % of patients having an objective response and 40 % of patients achieving durable disease control . | pertuzumab trastuzumab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Dapagliflozin seemed to play a role in accelerating the patient 's urinary sodium excretion as well as reducing gross fluid retention despite the fact that her nephrotic condition was resistant to furosemide . | Dapagliflozin furosemide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? PA combination of goserelin and tamoxifen in patients with relapsed ovarian cancer can not be recommended as standard therapy , but may result in long-term survival in individual patients . | goserelin tamoxifen are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In previous analyses of the MURANO study , fixed-duration venetoclax plus rituximab ( VenR ) resulted in improved progression-free survival ( PFS ) compared with bendamustine plus rituximab ( BR ) in patients with relapsed or refractory chronic lymphocytic leukemia ( CLL ) . | venetoclax rituximab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The aim of the present study was to determine whether a combination of atorvastatin and amlodipine causes sympathoinhibition via reduction of oxidative stress in the RVLM and improves cognitive dysfunction of hypertensive rats . | atorvastatin amlodipine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Active treatment consisted of hydrochlorothiazide ( 25 - 50 mg/day ) plus triamterene ( 50 - 100 mg/day ) with the addition of alpha-methyldopa ( 0.5 - 2.0 g/day ) in one-third of the patients . | hydrochlorothiazide triamterene alpha-methyldopa are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? It is predicted that patients suffering from both VL and cardiac disorders ( atrial fibrillation ) may benefit if they are treated with warfarin in conjunction with first-line antileishmanial therapies such as miltefosine and AmBisome . | warfarin miltefosine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? If concomitant therapy is absolutely necessary , the dose of digoxin should be halved prior to initiating dronedarone . | digoxin dronedarone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? All patients received neoadjuvant chemotherapy with cyclophosphamide , doxorubicin , and fluorouracil , or cyclophosphamide , doxorubicin , vincristine , and prednisone . | cyclophosphamide doxorubicin fluorouracil are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We analyzed 129 non-Hodgkin lymphoma patients who underwent AHSCT from 1996 to 2013 using the most common regimens : CBV ( cyclophosphamide , carmustine and etoposide ; n = 16 ) , BEAM ( carmustine , etoposide , cytarabine and melphalan ; n = 36 ) and BEAC ( carmustine , etoposide , cytarabine and cyclophosphamide ; n = 77 ) . | cyclophosphamide carmustine etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Early Prostate-Specific Antigen ( PSA ) Change at Four Weeks of the First-Line Treatment Using Abiraterone and Enzalutamide Could Predict Early/Primary Resistance in Metastatic Castration-Resistant Prostate Cancer . | Abiraterone Enzalutamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Dexamethasone , cytarabine , ifosfamide , and cisplatin as salvage therapy in non-Hodgkin lymphoma . | Dexamethasone cytarabine ifosfamide cisplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Cost-effectiveness of ribociclib plus letrozole | ribociclib letrozole are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We investigated whether lapatinib plus gemcitabine has synergistic or antagonistic effects on the pancreatic cancer cell lines MiaPaca-2 and PANC-1 . | lapatinib gemcitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The PANDORA trial has demonstrated that the combination of high dose pantoprazole with docetaxel is tolerable , but the clinical activity was not sufficient to warrant further testing . | pantoprazole docetaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Effective plasma levels of both saquinavir and lopinavir can be achieved by the co-administration of saquinavir soft-gel capsules and lopinavir/ritonavir . | saquinavir lopinavir are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In recent years several tyrosine kinase inhibitors targeting specific molecular pathways involved in its pathogenesis have been investigated , such as sorafenib , lenvatinib , and sunitinib . | sorafenib sunitinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The in vitro antibacterial activity of zidovudine alone and in combination with ciprofloxacin was investigated . | zidovudine ciprofloxacin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This patient was a case of primary antiphospholipid antibody syndrome in which endothelial cell damage was located exclusively in the capillary lumens and pulse cyclophosphamide therapy in addition to prednisolone and anticoagulant was effective . | cyclophosphamide prednisolone are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Vancomycin and gentamicin were administered systemically just prior to surgery and streptomycin was added to the irrigating solution . | Vancomycin gentamicin streptomycin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We observed a synergistic cytotoxic effect for the combination of foretinib and lapatinib on the viability and proliferation of the examined melanoma cell lines . | foretinib lapatinib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Following knockdown of ANXA2 in NB cell line SK-N-BE(2 ) using shRNA , we demonstrate enhanced drug sensitivity for doxorubicin ( 2.77-fold ) and etoposide ( 7.87-fold ) compared with control . | doxorubicin etoposide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Combined therapy with amiodarone and carvedilol provided greatest reduction of sudden arrhythmic and total mortality . | amiodarone carvedilol are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients with progressive refractory NSCLC who had previously benefitted from erlotinib ( objective response or stable disease > 8weeks ) were randomized to receive treatment with either erlotinib and sorafenib ( 400 mg orally twice daily ) or sorafenib alone . | erlotinib sorafenib are the drug combinations. Need more context. |