Datasets:
Update dataset card to use current project name
Browse files
README.md
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- protac
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- protein-degradation
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- benchmark
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pretty_name: PROTAC-
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size_categories:
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- 10K<n<100K
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# PROTAC-
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## Dataset Description
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PROTAC-
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## Evaluation Protocol
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```bibtex
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@inproceedings{protacbench2025,
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title={PROTAC-
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author={[Authors TBD]},
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booktitle={NeurIPS Datasets and Benchmarks Track},
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year={2025}
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- protac
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- protein-degradation
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- benchmark
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pretty_name: PROTAC-Bench
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size_categories:
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- 10K<n<100K
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---
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# PROTAC-Bench: A Cold-Target Benchmark for PROTAC Degradation Prediction
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## Dataset Description
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PROTAC-Bench is a merged PROTAC degradation dataset containing **10,748 entries** across **173 protein targets** (9,359 unique SMILES). It combines data from PROTAC-DB 3.0, Ribes et al. (2024), and DegradeMaster with deduplication and canonical SMILES standardization. Each entry has a binary activity label (active: DC50 < 1 μM OR Dmax > 50%) along with target UniProt ID and E3 ligase type (VHL/CRBN/Other). The dataset includes pre-computed 7-property ADMET cascade scores for all entries.
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## Evaluation Protocol
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```bibtex
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@inproceedings{protacbench2025,
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title={PROTAC-Bench: A Cold-Target Benchmark for PROTAC Degradation Prediction},
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author={[Authors TBD]},
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booktitle={NeurIPS Datasets and Benchmarks Track},
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year={2025}
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