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We conducted post hoc ( secondary ) analyses of unpublished data from a previously published randomized clinical trial ( NCT00477490 ) of desmopressin ( a medication used to treat nocturia ) and examined relationships between baseline and 4-week change in FUSP and PSQI global and subscale scores for participants ( N = 580 to N = 606 ) having complete data . | 2met
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( Multicenter Study to Rule Out Myocardial Infarction by Cardiac Computed Tomography [ ROMICAT-II ] ; NCT01084239 ) . | 4con
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Sixteen participants were prescribed benzodiazepines and/or zolpidem / zaleplon . | 3res
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Patients randomly received ( 1:1 ) pemetrexed ( 500 mg/m ( 2 ) ) plus cisplatin ( 75mg/m ( 2 ) ) for six 21-day cycles , followed by gefitinib maintenance or gefitinib monotherapy ( 250 mg/day ) . | 2met
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TW cost increase per case was $ 167 per instrument but averaged $ 700 per case . | 3res
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SMBG profiles once weekly or the disclosure of HbA ( 1c ) results did not improve glycaemic control in patients with type 2 diabetes on conventional insulin treatment , although indicators of hyperglycaemia increased the likelihood of therapy intensification . | 4con
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Six outcomes were examined : change in ADHD symptoms ( self/clinician ) , ADHD responder , Clinical Global Impression-Improvement ( CGI-I ) , change in mood , and change in Global Assessment of Functioning ( GAF ) . | 2met
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A prospective randomized controlled trial comparing the combination of radioisotope and blue dye versus radioisotope alone was performed between March 2010 and September 2012 . | 2met
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The prevalences of anaemia ( 42 [ 16 % ] vs 14 [ 11 % ] , respectively ) and rash ( 72 [ 27 % ] vs 33 [ 25 % ] ) were similar in the simeprevir and placebo groups . | 3res
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Women assigned to ATV/r had a higher risk of virologic failure with either nucleoside reverse transcriptase inhibitor backbone than women assigned to EFV , or men assigned to ATV/r . | 3res
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The PASS is a multicenter , prospective , phase three , randomized , open-label , blinded end-point ( PROBE ) trial of preventive antibiotic therapy in acute stroke . | 0bac
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A significant reduction in the overall dryness ( P < 0.001 ) and end-of-day dryness ( P = 0.047 ) was observed in subjects using the Systane Ultra lubricant eye drops compared with the control group . | 3res
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Future clinical trials should consider selective inclusion of high-risk patients . | 4con
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We performed a single-blind randomized clinical trial from April 24 , 2004 , through January 26 , 2010 , involving 1 year of treatment and 1 year of follow-up . | 2met
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Secondary peritonitis is an advanced form of complicated intra-abdominal infection ( cIAI ) requiring hospitalization , surgical source control , and empiric antibiotic therapy against causative aerobic and anaerobic bacteria . | 0bac
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However , participant attendance to sessions was good ( mean = 12.4 sessions of 14 offered ) . | 3res
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This trial seeks to test three innovative interventions , among clinicians registered to MacPLUS FS , to increase the quantity and quality of searching for current best evidence to answer clinical questions . | 1obj
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On the other hand , a significant improvement of global longitudinal strain was observed earlier than the above indexes at 3 , 6 , and 12 months . | 3res
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Chinese Clinical Trial Registry ( http://www.chictr.org/en/ ) ChiCTR-TRC-10000937 . | 0bac
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Eleven retrospectively identified subjects with RV disease were included as a pilot population . | 2met
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Flow-mediated dilatation of the brachial artery increased in the intervention group as compared with the control group ( +2.9 % ; 95 % confidence interval , +2.1 to +3.6 % ; P < 0.001 ) , whereas there was no significant change in systemic inflammation . | 3res
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Criterion measurements were taken on day 2 , before and immediately after performance of the eccentric-exercise protocol ( 10 sets , 10 repetitions using 120 % 1RM ) and after the recovery period . | 2met
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Forty-eight ( 89 % ) of the fifty-four postgraduate year-3 residents from seven academic institutions completed the study . | 3res
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Resource use was assessed prior and during treatment to determine direct and absenteeism costs . | 2met
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For polyps measuring 5 mm , the accuracy was 79.4 % for NBI and 80.1 % for FICE ( P = 0.835 ; sensitivity 81.9 vs. 74.5 % , P = 0.064 ; specificity 75.7 vs. 88.4 % , P = 0.006 ) . | 3res
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Recruited patients will receive treatment accordingly . | 2met
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Among observers , the frequency of identical consecutive readings for systolic or diastolic BP varied from 0 to 4.2 % . | 3res
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The primary end point was the time when sensor glucose was in target range between 3.9 and 10.0 mmol/L during the 7-day home phase . | 2met
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We studied 35 subjects ( randomly divided into two groups ) , affected by traumatic or vascular brain injury , having attended from January 2010 to December 2012 the Laboratory of Robotic and Cognitive Rehabilitation of IRCCS Neurolesi of Messina . | 2met
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Mean dose to the whole and inferior rectum correlated with declines in bowel QOL while dose to the mid and superior rectum did not . | 3res
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To investigate the effect of wholegrain rye consumption on appetite and colonic fermentation after a subsequent meal . | 1obj
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On the 10th day after surgery , the mastery rates of the health knowledge of the two groups were 96.7 % and 50.0 % , respectively , the difference was statistically significant ( 2 = 16.86 , P < 0.001 ) . | 3res
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Further , enrollment was very slow ( until 12months between two patients ) and new insights showed an apparent benefit of intratympanic gentamicin treatment ( ITG ) . | 3res
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After treatment , Ccr in the acupuncture and moxibustion group was higher than that before treatment ( P < 0.05 ) and higher than that in the western medication group ( P < 0.05 ) . | 3res
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The results from the post-drug assessments suggest that a combination of ibuprofen and caffeine was the optimum treatment for malaise associated with URTIs in that it had significant effects on objective performance and subjective measures . | 4con
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This study appears to be the first to quantify this by using PPT and MAS . | 4con
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The findings of this pilot study support the feasibility of a randomized , double-blind , controlled trial . | 4con
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Bevacizumab and ranibizumab had equivalent effects on visual acuity at 1 year when administered according to a treat-and-extend protocol . | 4con
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An increase in peak VO2 at 3 months was present in women and men in the ET group ( mean SD ; median , 0.88 2.2 , 0.80 and 0.77 2.7 , 0.60 , respectively , women vs. men ; p = 0.42 ) . | 3res
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Analysis by subsites indicated that this difference favoring the S arm was mainly driven by survival data among patients with cancers of the oral cavity and maxillary sinus . | 3res
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The combination of daclatasvir/peginterferon-alfa/ribavirin was generally well tolerated and achieved higher SVR24 rates compared with placebo/peginterferon-alfa/ribavirin among patients infected with HCV genotype 1 or 4 . | 4con
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SSIs cause substantial morbidity , prolonged hospitalization , and costs and remain one of the most frequent surgical complications . | 0bac
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No cases of tuberculosis , herpes zoster , opportunistic infections or deaths were reported . | 3res
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None of patients had any serious complications . | 3res
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The mean overall clearance rate was 74.1 % , 68.8 % , and 64.6 % on Week 4 , 8 , and 12 , respectively , in the 110 treated sides . | 3res
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Cardiovascular parameters were collected via electrocardiograms , Holter monitoring ( three lead Holter monitor ) and vital signs . | 2met
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Cyclosporine , a potent inhibitor of the opening of the mitochondrial permeability transition pore , attenuates reperfusion injury in patients with acute ST-segment elevation myocardial infarction . | 0bac
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The objective of this study is to evaluate the effectiveness of the face-to-face guidance strategy and the e-guidance strategy on the primary outcome measure : use of ergonomic measures by individual construction workers , and on the secondary outcome measures : the work ability , physical functioning and limitations due to physical problems of individual workers . | 0bac
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Chinese women with a singleton vertex foetus at the gestation of 37 weeks or above were recruited . | 2met
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Higher FGF23 concentrations were associated with higher risk of cardioembolic but not with other stroke subtypes in community-dwelling adults . | 4con
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There was no significant difference in the success rate of CBD clearance ( 93.6 vs. 94.6 % , p = 0.76 ) or the complication rates ( 3.6 vs. 5.1 % , p = 0.527 ) between the groups . | 3res
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Aerobic capacity increased after AT ( P < 0.001 ) but was lost during the follow-up observation period . | 3res
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In an international trial , we randomly assigned 950 unconscious adults after out-of-hospital cardiac arrest of presumed cardiac cause to targeted temperature management at either 33C or 36C . | 2met
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This study aims to describe the rationale , design , and baseline findings of an email-linked website intervention to improve modifiable cancer risk factors . | 0bac
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Bioequivalence was assessed based on 90 % confidence intervals , according to two one-sided t-tests . | 2met
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Biomicroscopy assessments were similar at baseline for both groups . | 3res
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The primary endpoint was the reduction of HbA ( 1c ) compared with baseline after 12 months . | 2met
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Participants were assessed preintervention and postintervention on their ability to identify the sciatic nerve and other anatomic structures on static US images , as well as their ability to locate the sciatic nerve with US on live models . | 2met
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No patients had AF recurrence before this time . | 3res
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The primary safety end point was the 30-day composite rate of death , reinfarction , ischemia-driven target vessel revascularization , major bleeding , sepsis , pneumonia , peritonitis , severe arrhythmia , or renal failure . | 3res
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Fewer than 60 % of physicians correctly answered questions on whether small businesses receive tax credits for providing health insurance , the effect of the PPACA on Medicare benefits , and whether a government-run health insurance plan was created . | 3res
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In multivariable analysis , baseline RHR was independently associated with MCEs ( HR 1.1 per 10min ( -1 ) faster , 95 % CI : 1.0-1 .3 ) and cardiovascular mortality ( HR 1.3 per 10min ( -1 ) faster , 95 % CI : 1.0-1 .7 , both p0 .03 ) . | 3res
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Prospective randomized trial . | 2met
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We developed and internally validated a score for prediction of risk of rehospitalisation and mortality in hospitalised older people . | 4con
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Hyperkalemia and doubling of creatinine were more likely and hypokalemia was less likely in patients receiving spironolactone in the Americas with no significant treatment effects in Russia/Georgia . | 3res
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Admission rate in the 3 % HS group was 28.9 % compared with 42.6 % in the NS group ( adjusted odds ratio from logistic regression , 0.49 [ 95 % CI , 0.28-0 .86 ] ) . | 3res
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The hemodynamic parameters were maintained within normal limits during operation in group A ( P < 0.05 ) . | 3res
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Prophylactic administration of maropitant does not reduce the frequency of adverse events and maropitant should be administered only as required for individual cases . | 4con
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Several web-based interventions for MDD have shown to be effective in reducing depressive symptoms . | 0bac
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To evaluate the safety and efficacy of ixmyelocel-T in 2 prospective randomized phase 2A Trials administered via minithoracotomy or intramyocardial catheter injections in patients with dilated cardiomyopathy ( DCM ) stratified by ischemic or nonischemic status . | 1obj
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Lysholm scores were not significantly different between groups at 12 weeks ( P = .81 ) , but the DN group had improved significantly more than the PRP group at 26 weeks ( P = .006 ) . | 3res
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The objective of this post hoc analysis of our randomized control trial was to determine whether rapid diagnosis and treatment of IS could limit the incidence of ASD while identifying risk factors related to ASD outcome . | 1obj
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NCT00694343 ( http://clinicaltrials.gov ) . | 0bac
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Practitioners should take account of the complex relationship between diabetes-specific QoL and glucose , particularly with regard to dietary behaviour . | 4con
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IRB approval was obtained at the Wexner Medical Center at Ohio State University for a prospective , randomized , single-blinded , controlled clinical study of 48 healthy adult volunteers undergoing tonsillectomy for chronic tonsillitis and tonsil hypertrophy . | 2met
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KT after OMF surgery is a promising , simple , less traumatic , economical approach free from systemic adverse reaction upgrading patients ' quality of life . | 4con
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Further studies are needed to evaluate the longer-term clinical outcomes and safety of this approach for LDL-C lowering . | 4con
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Eight research horses and 35 client-owned horses . | 2met
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We sought to assess the agreement between TTE ( CFRTTE ) and invasive thermodilution-derived CFR ( CFRThermodilution ) as well as their association with index of microcirculatory resistance ( IMR ) in mid-term follow-up after percutaneous coronary intervention for acute coronary syndrome . | 1obj
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We performed a randomized controlled trial from March 2010 to March 2011 in an outpatient clinic at a university hospital . | 2met
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The rate of weight loss does not affect the proportion of weight regained within 144 weeks . | 4con
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Self-reported past-7-day tobacco abstinence 9 months after randomization ( `` quitting '' ) , assessed by automated caller or blinded study staff . | 2met
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The primary end point was the proportion of patients with sustained remission in the double-blind phase . | 2met
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Importantly , a strong and persistent decrease of CD4 cell counts ( p < 0.0005 at 5 years ) was independently associated with ATG induction ( logreg p = 0.002 ) but not related to functional CD4 cell impairment ( helper activity/cytokine production ) or an increased risk of infection . | 3res
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Pidotimod is a synthetic immunostimulant . | 1obj
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Multivariate logistic regression analyses were performed for accuracy in predicting needs for LSIs in control and WVSM subjects . | 2met
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After adjustment of clinical risk factors , notably , CAC score , multivariate regression analysis showed EAT volume was an independent predictor of CAD severity in this sample ( odds ratio 11.2 , 95 % confidence interval 1.7-73 .8 , p = 0.01 ) . | 3res
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The overall response rates were 57.1 % for arm A ( 95 % CI = 37 % -76 % ) and 61.4 % for arm B ( 95 % CI = 48 % -74 % ) . | 3res
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The incidence of postoperative significant bacteruria ( p = 0.020 ) , dysuria ( p = 0.030 ) , burning on micturition ( p = 0.016 ) , urinary frequency ( p = 0.031 ) , and urgency ( p = 0.011 ) were significantly lower in group A compared with group B. | 3res
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The number of negative appendectomies was 12 ( 9.16 % ) in group A versus 5 ( 3.6 % ) in group B ( p = 0.063 ) . | 3res
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Following 8 weeks of yoga practice , participants in the yoga intervention group showed significantly improved performance on the executive function measures of working memory capacity and efficiency of mental set shifting and flexibility compared with their stretching-strengthening counterparts . | 4con
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Eligible subjects were within 2 months of diagnosis of primary breast cancer or recurrence . | 2met
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University hospital . | 2met
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anzctr.org.au Identifier : ACTRN12611000398909 . | 0bac
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The average patient compliance to statins , clopidogrel and aspirin was recorded as 74.28 % , 69.7 % and 68.66 % , respectively during discharge and follow-up visits . | 3res
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Pan-African Clinical Trials Registry : PACTR201102000277177 ( www.pactr.org ) . | 0bac
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In the overall diet , PB increased dietary fiber and - glucan compared with controls ( p < 0.05 ) . | 3res
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Case control findings from interviews seven years post-partum indicate that mothers of children with FASD are significantly more likely than randomly-selected controls or community mothers to : be shorter ; have higher body mass indexes ( BMI ) ; be married to a man with legal problems ; report more drinking three months pre-pregnancy ; engage in more current drinking and drinking alone ; and have alcohol problems in her family . | 3res
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Older adults were interested in keeping track of their health and medication information . | 3res
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There were no differences between the outcomes of the two centres with exception of prosthesis failures and complications in the maxilla . | 3res
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