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The endothelial damage was more often in EC than in RF group as in the patients older than 66 years of age . | 4con
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To close this gap , we developed a web-based parenting program for parents entitled `` Making a healthy deal with your child '' . | 0bac
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The milk transfer rate in the three intervention groups was greater than in the control group ( F3 ,363 = 15.37 ; p < 0.001 ) . | 3res
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No serious side effects were observed in the two groups during the treatment period . | 3res
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No significant effects were seen in secondary outcomes . | 3res
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The discrimination for both scores was poor for 30-day/in-hospital and 1-year mortality . | 3res
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The therapeutic efficacy was compared between the two groups . | 2met
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After this critical time point and finish of oncological treatment , a marked difference in the development of patients treated with PEG . | 3res
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Peak oxygen consumption , flow mediated dilation ( endothelial function ) , and glucose homeostasis were assessed in 19 patients ( 557 years ) before and after an 8-week intervention . | 2met
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The baseline and follow-up computed tomographic ( CT ) scan images were reviewed centrally and blinded to any clinical information . | 2met
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Aerobic and breathing exercises have been demonstrated to benefit asthmatic patients ; however , there is no evidence comparing the effectiveness of these treatments . | 0bac
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MSE increased significantly more in the experimental group and remained significantly higher than in the control group after 6 and 12 months ( B = 0.42 ; P = .010 ) . | 3res
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Secondary outcome measures were : pain at rest and during flexion of the knee , worst pain experienced during a 5-m walk , patient 's evaluation of muscle strength during walk , and amount of sufentanil administered during the 90-min study period . | 2met
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Moreover , HSL was responsible for a partial recovery from endothelial dysfunction , as indicated by the significant decrease in sVCAM-1 . | 3res
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It is therefore unclear whether human immunodeficiency virus type 1 ( HIV-1 ) vaccination would elicit similar responses in adults and infants . | 0bac
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No other treatment group differed significantly from the nonencouraged control group , whereas encouraging effort produced significantly increased vergence ( P = 0.004 ) and accommodation ( P = 0.005 ) gains in the second control group . | 3res
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Compared with the western medication group , the symptom score of NDI was reduced obviously after treatment and in each time point of follow-up in the acupuncture group ( P < 0.05 , P < 0.01 ) , and the score of life quality was increased obviously ( P < 0.05 , P < 0.01 ) . | 3res
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Of 222 patients who underwent randomisation , 217 were assessable 2 h after the start of acetylcysteine treatment . | 3res
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There is currently no evidence-based research to guide or improve communication between public health agencies and HCPs . | 4con
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In the study group , total opioid and diclofenac consumption was lower ( P < 0.001 ) , and blood pressure and heart rate were lower ( P < 0.001 ) compared to the control group . | 3res
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To define the efficacy of the HPV vaccine through cross-immunization and its role in clearance of HPV infection , and to assess infection-associated factors in men . | 1obj
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Although body weight was reduced similarly in both groups , the BB group showed greater HbA1c and systolic blood pressure reductions ( HbA1c : -4.62 % vs. -1.46 % , p = 0.047 ; SBP -9.58 vs. -2.43 mmHg ; p = 0.04 ) . | 3res
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As compared with MPT , continuous lenalidomide-dexamethasone given until disease progression was associated with a significant improvement in progression-free survival , with an overall survival benefit at the interim analysis , among patients with newly diagnosed multiple myeloma who were ineligible for stem-cell transplantation . | 4con
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The relative risk and number needed to treat were 2.57 ( 95 % confidence interval , 1.79-3 .70 ) and 3.25 ( 95 % confidence interval , 2.44-4 .89 ) , respectively . | 3res
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Process variables were evaluated by independent raters on the basis of videotapes of the first three treatment sessions . | 2met
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Mean baseline SBP and DBP were 136.518.3 vs 134.220.1 mmHg ( p = 0.1 ) and 79.110.2 vs 78.210.1 mmHg ( p = 0.4 ) in the bimatoprost and LTFC groups respectively . | 3res
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With no weight loss differences between conditions , analyses used the combined sample . | 3res
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Given the long natural history of prostate cancer , we assessed differing graphical formats for imparting knowledge about the longitudinal risks of prostate cancer recurrence with or without ` hormone ' or ` androgen deprivation ' therapy . | 1obj
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Seventy-two patients were randomly allocated to one of four groups : 10 % lidocaine was sprayed either on the laryngoscope blade ( group L ) , on the trachea ( group V ) , or on the laryngoscope blade and the trachea ( group LV ) . | 2met
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The study population included 110 eyes of 55 patients with myopia with and without astigmatism . | 2met
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The Neuropsychiatric Inventory ( NPI ) , Clinical Global Impression-Improvement scale ( CGI-I ) and standard safety measures were secondary outcomes . | 2met
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In phase I subjects/volunteers , all psychiatric TEAEs were mild or moderate . | 3res
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The relationship between subject-reported changes in PDQ psychosexual symptoms and clinical response to Peyronie 's disease ( PD ) treatment was examined . | 1obj
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SD OCT corneal power maps showed steepening at 3 and 9 months along with mild myopic shift . | 3res
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Quality of surgical upper lip scars , which are oriented perpendicular to the direction of pull of the underlying orbicularis oris muscle , is significantly improved by its temporary paralysis during wound healing . | 4con
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MOR103 was well tolerated and showed preliminary evidence of efficacy in patients with active RA . | 4con
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The first group ( n = 22 ) received 5 mL of lidocaine 2 % while the second group ( n = 25 ) received 4 mL of lidocaine 2 % + 1 mL of betametazone under the guidance of ultrasound . | 2met
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Among the 165 patients treated by linezolid ( 57.6 % ) in the PP population , 95 were clinically cured at the end of the study , compared to 81 of the 174 patients treated by vancomycin ( 46.6 % ) ( IC 95 % of the difference 0.5 % -21.6 % , P = 0.042 ) . | 3res
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The primary efficacy end point was the change in A1C from baseline versus placebo ; secondary end points included corresponding changes in fasting plasma glucose ( FPG ) levels , stratification by baseline A1C , and percentage of A1C responders . | 2met
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For HER2-normal tumors , median PFS did not differ by treatment arm ( 4.1 v 3.8 months ) . | 3res
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Effect ( Cohen 's d ) of exercise on both optimism and hopelessness was moderate for the majority of exercises . | 3res
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In patients with ischemic stroke with a proximal cerebral arterial occlusion and salvageable tissue on CT perfusion imaging , early thrombectomy with the Solitaire FR stent retriever , as compared with alteplase alone , improved reperfusion , early neurologic recovery , and functional outcome . | 4con
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Primary outcome was assessed by questionnaire following a task directing attention away from the handover . | 2met
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The overall aim of the study is to investigate the therapeutic potential of motor-cognitive approaches ( mental practice or mirror therapy ) on hand function after wrist fracture . | 0bac
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The anesthesia breathing circuit was switched and the procedure repeated . | 2met
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This trial was registered with the ISRCTN register , number ISRCTN20687662 . | 2met
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The Bland-Altman limits of agreement for PSG-AHI ( in events per hour ) were [ -14.1 to 32.4 ] . | 3res
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This study evaluated the efficacy of a probiotic containing Bacillus toyonensis spores ( Toyocerin ( ) ) in postweaning piglets against enteric pathogens . | 1obj
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Two antenatal clinics in Gothenburg , Sweden . | 2met
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Fifty-two patients with DME were enrolled and randomized to an IVB group ( n = 26 ) and an IVB+TRP group ( n = 26 ) . | 3res
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321seven-year-old schoolchildren . | 2met
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Retrospective and observational studies suggest that early implementation of renal replacement therapy could improve the prognosis for these patients . | 0bac
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Spinal and general anesthesia as well as peripheral blocks are successfully used in foot surgery . | 0bac
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There was a slight increase in the PPI-VAS scores of the PTNS group at 6-month , but the difference was not statistically significant . | 3res
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Although a number of treatment protocols are currently used , none have been formally investigated . | 0bac
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Three hundred twenty-three patients were randomized and received treatment ; placebo ( n = 110 ) , PGB-CR 330 mg ( n = 100 ) , PGB-CR 165 mg ( n = 113 ) ; and 287 ( 88.9 % ) completed the trial . | 3res
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At the end of a structured intensive course in emergency medicine , students of trained clinical teachers performed worse in 2 of 4 practical SCE domains compared to students of untrained teachers . | 4con
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Eighty female , chemotherapy-nave breast cancer patients ( median age 49 , range 24-67 years ) scheduled for four or five courses of adjuvant 3 weekly doxorubicin plus cyclophosphamide ( AC ) chemotherapy , were randomly assigned to receive 80mg PC-SOD ( human recombinant SOD bound to lecithin ) or placebo , administered intravenously ( i.v. ) immediately prior to each AC course . | 3res
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To examine the influence of discrimination on adoption of healthy behaviors among low-income Black hypertensive patients . | 1obj
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We conducted a randomized placebo-controlled trial in 12 UK centers ( 2008-2011 ) . | 2met
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At baseline , 56.6 % , 60.1 % and 61.5 % of placebo , CZP 200mg Q2W and CZP 400mg Q4W patients were employed . | 3res
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The study encompasses process - and effect-evaluations as well as health economic analyses . | 2met
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A higher cholesterol level at baseline was the only independent predictive factor of MACEs related to the target SVG ( P = 0.016 ) . | 3res
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Randomised controlled trial . | 2met
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Urinary sodium excretion was 155 58 mmol/24 h US vs 113 45 mmol/24 h RS ( p = 0.002 ) . | 3res
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A randomised , double-blinded , prospective , placebo-controlled study . | 2met
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Treatment continued until progression or unacceptable toxicity . | 2met
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Two patients of group A and eight patients of group B were excluded from the final analysis . | 3res
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Median age of all patients was 72 years ( range 53-88 ) . | 3res
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A Bayesian algorithm was used for randomization and dose selection . | 2met
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Uptake on SPECT was graded in 17 segments on a 5-point scale ( 0 , normal ; 4 , absent ) and assessed as BMIPP summed scores ( SS ) . | 2met
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No significant co-regulation occurred in any group at any holding session or over time . | 3res
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Compliance with the FV intervention was determined with use of self-reported FV intake and biomarkers of micronutrient status . | 2met
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Arterial perfusion ( AP ) of tumors derived from CT perfusion and tumor diameters were measured on CT perfusion before and after transarterial radioembolization . | 2met
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A 4-week cycling regimen can normalize the modulation of reciprocal inhibition and functional performance in individuals with SCA . | 4con
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Mean ( SD ) age was 30 ( 10 ) years , and 50 % were men . | 3res
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Twenty patients in each group were recruited in the study . | 3res
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Both treatments were generally well tolerated , with safety profiles consistent with those observed in previous studies . | 4con
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Predictive variables for reversal to NGT-24 m were good baseline - cell function ( odds ratio [ OR ] 2.79 [ 95 % CI 2.30-3 .40 ] ) and its further improvement ( OR 5.70 [ 95 % CI 4.58-7 .08 ] ) , and NGT-6 m ( OR 2.10 [ 95 % CI 1.14-3 .83 ] ) . | 3res
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In 2010 , the African Meningococcal Carriage Consortium ( MenAfriCar ) conducted cross-sectional surveys in urban and rural areas of seven countries . | 2met
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Prospective , randomized , 22 factorial-design trial with explicit methods ( July 1 , 2012 , to April 15 , 2014 ) at 10 International Network for Simulation-Based Pediatric Innovation , Research , & Education ( INSPIRE ) institutions running a standardized simulated CPA scenario , including 324 CPR-certified health care professionals assigned to 3-person resuscitation teams ( 108 teams ) . | 2met
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Nutritional status , body weight , body mass index , serum albumin were performed at the beginning of the study and at a two-year follow-up . | 2met
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TTR of patient after an abnormal breast , cervical , or colorectal screening test and the clinics ' patient and provider characteristics were obtained . | 2met
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Precut techniques have been used to facilitate biliary cannulation during difficult endoscopic retrograde cholangiopancreatography . | 1obj
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The primary and secondary outcomes of the three groups at follow-up were assessed . | 2met
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Dexmedetomidine , a potent selective 2-adrenergic agonist , produces sedation and analgesia . | 1obj
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Both groups agreed there was a need for VATS lobectomy training in thoracic residency programs and in standardized workshops . | 3res
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The medication group ( 28 cases ) was treated with oral administration of pinaverium ( 50 mg each time , 3 times a day ) and live combined bifidobacterium and lactobacillus tablet ( 4 tablets each time , 3 times a day ) . | 2met
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To assess the superiority of fesoterodine 8 mg vs 4 mg for improvement in urgency urinary incontinence ( UUI ) episodes and other diary variables , diary-dry rate ( proportion of patients with > 0 UUI episodes on baseline diary and 0 UUI episodes on post-baseline diary ) , and improvements in measures of symptom bother , health-related quality of life ( HRQL ) , and other patient-reported outcomes ( PROs ) . | 1obj
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There were no significant differences between the clinical , laboratory and B-mode and Doppler US parameters at peak time and trough time ( P = 0.132-0 .986 ) . | 3res
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Of 1083 patients enrolled , 800 ( 739 % ) , of whom 656 ( 820 % ) had pyelonephritis , were included in the microbiological MITT population . | 3res
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The difference in PRI was not significant after treatment between the two groups ( all P > 0.05 ) . | 3res
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Primary outcome was self-reported individual-level adherence to physical-activity guidelines averaged over 6-month and 12-month post-intervention assessments . | 2met
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After a median follow-up of 12.6 y , 144 incident skin cancers were diagnosed . | 3res
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Prospective , randomized , clinical trial . | 2met
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The reported postoperative complications included swelling in 19 % and minor bleeding in 6 % without significant differences between the two laser modes . | 3res
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A total of 75 patients registered in the COMPASS study who underwent surgical resection were examined in this study . | 3res
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However as far as prevention of hypertension is concerned , reducing body fat ( rather than only body weight ) may remain an important measure to prevent hypertension as body fat mass is reducible while lean body mass may not be reducible and , in long term , obesity itself can lead to hypertension by various mechanisms . | 4con
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Patients , treating physicians , and study investigators were masked to treatment allocation . | 2met
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We randomized 177 buprenorphine-treated opioid dependent participants with cocaine dependence or abuse to 12 weeks of double-blind treatment with disulfiram 250mg daily ( n = 91 ) or placebo ( n = 86 ) . | 2met
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