OxAISH-AL-LLM/pubmed_20k_rct · Datasets at Hugging Face

text stringlengths 2 1.45k	label class label 5 classes
We hypothesize that limited transthoracic echocardiogram ( LTTE ) is a useful tool to guide therapy during the initial phase of resuscitation in trauma patients .	0bac
Children aged 6 to < 36 months and 36 to < 72 months received 0.25 mL and 0.50 mL doses , respectively .	2met
The functional outcome is better in comparison to the that with other treatments and it is a cost-effective treatment .	4con
In the routine acupuncture group , the routine acupuncture technique was adopted at the main acupoints , such as Shangxing ( GV 23 ) , Baihui ( GV 20 ) , Dicang ( ST 4 ) , Quchi ( LI 11 ) , Huantiao ( GB 30 ) and Zusanli ( ST 36 ) , etc. .	2met
Assessments will be conducted prior to ( week 0 ) , mid-way through ( week 6 ) and following the intervention period ( week 12 ) as well as at a four week follow-up ( week 16 ) .	2met
Intention-to-treat and per-protocol analyses showed an improved salivary flow rate by 0.04 ml/15 min ( 95 % CI : -0.49 to 0.58 ml/15 min ) and 0.04 ml/15 min ( 95 % CI : -0.52 to 0.60 ml/15 min ) , respectively , but the differences were not significant .	3res
We recorded the times of treatments in different groups respectively .	2met
Secondary outcome measures include disease activity , quality of life , adherence to treatment , use of the telenursing service , and cost .	2met
Study parameters were recorded at baseline , immediately after treatment , and after 15 weeks .	2met
No improvements in response or disease control rates , PFS , or OS were gained from the addition of mapatumumab .	3res
A moderate iron chelation regimen that avoids changes in systemic iron levels may constitute a novel therapeutic modality for PD .	2met
Institutional experience substantially influences survival in locally advanced HNC .	4con
Median percent reduction was -28.7 % for placebo , -38.2 % ( P = 0.08 vs placebo ) for once-daily SPN-804 1200 mg , and -42.9 % ( P = 0.003 ) for SPN-804 2400 mg .	3res
Three months postoperatively , the mean reduction in corneal astigmatism was 0.67 diopter ( D ) 0.58 ( SD ) in the toric group and 0.18 0.52 D in the nontoric-OCCI group .	3res
The culture in many team sports involves consumption of large amounts of alcohol after training/competition .	0bac
This learning attenuation diminished during the following learning sessions .	3res
Thus , the advantage of HIIT with regard to time efficiency seems debatable when considering transient HIIT-induced impairments of neuromuscular function .	4con
The prevalence of PFO ( 32 % ) was similar to that reported in low-altitude populations and was not different in participants with and without chronic mountain sickness .	3res
Univariate and multivariate ordinal regression analyses were performed to identify predictors of symptomatic and asymptomatic ICAS based on clinical , laboratory and radiologic data .	2met
To examine adherence to , satisfaction with , and preliminary efficacy of mobile phone short message service ( SMS ) to promote health behaviors in school-aged children .	1obj
As far as is known to the authors , this is the first health economic evaluation of a health promotion intervention targeting physical activity and healthy eating in individuals with mental disorders .	4con
The percentage of patients with PTS in the SM group ranged from 14.9 % ( 1 year after the end of anticoagulation ) to 19.5 % ( 60 months ) .	3res
Individuals treated with VEN-XR had more severe withdrawal-like symptoms , which mediated their continued marijuana smoking .	4con
IMNs and OAR were contoured in 68 planning CT scans .	2met
Subjects were assessed with measures of nicotine and gambling severity and followed for 3 months after treatment .	2met
The comparative analysis of strain-lines pattern suggests that the enhancement of LV function is achieved by a more synchronous recruitment of both left - and right-handed helical fibers .	3res
526 participants with IA will be recruited from British Columbia , Alberta , and Ontario in Canada .	2met
Common clinical practice recommends dual antiplatelet therapy ( DAPT ) for transcatheter aortic valve implantation ( TAVI ) .	0bac
Gloves were tested by the water leak test .	2met
Sensitivity , specificity , and positive predictive value ( PPV ) were calculated relative to two outcomes : cancer status and consensus of three experts about recall .	2met
Similarly , no treatment differences in muscle protein-bound L - [ 1 - ( 13 ) C ] - phenylalanine enrichments were observed at 120 min ( 0.003 0.001 vs. 0.002 0.001 ) or 300 min ( 0.015 0.002 vs. 0.016 0.002 mole percent excess ) after Cas + Serum vs. Cas .	3res
About one half of those who develop adult-onset moyamoya disease experience intracranial hemorrhage .	1obj
Complication rates and NAC outcomes ( tumor size changes , 2-year disease-free survival rate , and 2-year overall survival rate ) were compared between the two groups .	2met
ATT estimates adjusting for this were 6.2 % ( 95 % CI -1.6 to 14.0 ) and 10.4 % ( 95 % CI 2.2 to 18.5 ) , respectively .	3res
Adverse events and neurologic test data were reported .	2met
Alogliptin efficacy was sustained over 2 years in patients with inadequate glycaemic control on metformin alone .	4con
SSI developed in 2 of 100 patients ( 2 % ) in the antibiotic prophylaxis group and 13 of 100 patients ( 13 % ) in the placebo group , indicating a significant difference between the 2 groups ( relative risk ratio , 0.25 ; 95 % confidence interval , 0.070 to 0.92 ; P = .003 ) .	3res
Moreover , in the same group a statistically significant disc shrinkage was shown by IDVA in sixth months of follow-up ( p < 0.05 ) .	3res
Descriptive laboratory study .	2met
No support was found for improved efficacy or support .	3res
The aim of this study was to evaluate factors associated with weight gain among breast cancer survivors prior to enrolling into a behavioral weight loss intervention .	1obj
A prophylactic fixed rate infusion regimen may not improve hemodynamic control ; a variable rate regimen adjusted in response to changes in arterial blood pressure and heart rate may allow more accurate maintenance of baseline blood pressure .	0bac
Comparable mipomersen post-distribution phase plasma concentrations were observed across the 3 dose regimens suggesting similar tissue exposure .	3res
Primary stability of the TADs as measured by placement torque , amount of tooth movement , and age of the patients did not influence displacement of the TADs .	3res
Older age , prior hemorrhage , prior stroke or transient ischemic attack , diabetes , lower creatinine clearance , decreased hematocrit , aspirin therapy , and nonsteroidal anti-inflammatory drugs were independently associated with an increased risk .	3res
This randomised controlled trial will evaluate the effectiveness of an education program on knowledge , self-care and health-related quality of life of Thai HF patients and their carers .	2met
The aim of our study was to compare the effect of oral clonidine and 1/V fentanyl with oral placebo and I/V fentanyl in attenuating the haemodynamic responses to laryngoscopy and intubation in known hypertensive patients .	0bac
Compared to Group D , the heart rate and rate pressure product were significantly lower in Groups M1-M3 .	3res
Fluvoxamine appears to be less effective than citalopram ( p = 0.036 ) , paroxetine ( p = 0.037 ) , clomipramine ( p = 0.05 ) , sertraline ( p = 0.011 ) , and duloxetine ( p = 0.024 ) .	3res
Five patients in the cidofovir group and seven in the imiquimod group either withdrew or were lost to follow-up before the first 6-week safety assessment .	3res
The aim of the extension study was to evaluate different timings for heterologous AS03A-adjuvanted booster vaccination ( A/Indonesia/5 / 2005 ; clade 2.1 ) given at Month 6 , 12 , or 36 post-primary vaccination .	2met
Unique identifier : NCT 01065532 .	0bac
However , there is no sufficient evidence obtained from randomized controlled trials to confirm the role of De Qi in the treatment of acupuncture for tinnitus .	0bac
Patients 12 years old with partial-onset seizures despite treatment with 1-3 antiepileptic drugs at baseline completed a perampanel phase III trial and entered extension study 307 ( NCT00735397 ) .	2met
Short periods of muscle disuse , due to illness or injury , result in substantial skeletal muscle atrophy .	1obj
There was no change in visual acuity between pre - and post-treatment measurements among the study groups .	3res
Both groups completed 3 training sessions per week .	2met
Merck KGaA , Darmstadt , Germany .	0bac
There were no significant differences in total time of assisted ventilation and duration of oxygen therapy between the two groups ( P > 0.05 ) .	3res
No differences in fetal measurements at 36 wk of gestation were observed between the groups , except for body weight and its increment from 23 to 36 wk , which were higher in the supplemented group ( 6.8 % , P = 0.014 and 10.5 % , P = 0.07 , respectively ) .	3res
An anticholinergic agent or antidiuretic agent as an add-on therapy in men previously treated with an alpha-blocker improves nocturia including LUTS .	4con
Nondiabetic pseudophakic patients with definite POAG were recruited ; 29 eyes of 16 individuals participated in study 1 .	2met
Within the first and second periods , the body weight of the patients was observed an increase of 0.4 and 1.6 kg with once-daily dose , whereas a decrease of 0.1 and 2.1 kg in the twice-daily dose , in the same period .	3res
Other assessments included , Clinical Global Impression-Severity ( CGI-S ) , Global Assessment of Functioning ( GAF ) , and Drug-Induced Extrapyramidal Symptoms Scale ( DIEPSS ) .	2met
The operating properties of 2 - and 3-item PRO were evaluated using data from a trial of methotrexate in CD .	2met
This trial was registered at clinicaltrials.gov as NCT01655901 .	4con
Crushing ER OC/APAP further delayed onset of subjective effects compared with intact ER OC/APAP .	4con
In the absence of a definitive `` gold standard '' for the judgement , it is desirable to try and bring novice professionals ' judgemental risk thresholds to the level of competent professionals as quickly and effectively as possible .	0bac
The levels of LPS , TNF-alpha , and IL-6 were lower in the TM group than in the control group at post-operative 96 h ( P < 0.05 ) .	3res
Morphine seems to be more effective at 2 and 4 hours , but after 4 hours they have similar effects , the satisfaction difference between both groups was not significant in the patients .	4con
Participants lost approximately 4.7 2.2 kg ( p < 0.001 ) .	3res
The implants were restored with screw-retained single crowns after 4 months .	2met
No vaccine-related serious adverse events were reported .	3res
RCO resulted in a markedly increased pressor response in HF relative to controls , due primarily to an increase of SBP and attenuated cardiac recovery as noted by the persistent elevation in HR .	4con
Intervention group : The doses of erythropoietin , iron , and vitamin C were adjusted every month based on the ferritin and hemoglobin ( Hb ) levels according to the protocol .	2met
A 6-month aerobic and resistance training exercise regimen was implemented to examine interrelationships between circulating sex hormones , body composition , aerobic capacity , insulin sensitivity , and insulin resistance .	1obj
The trial is registered with ClinicalTrials.gov NCT00757159 .	4con
The median age was 68 , and the median follow-up time was 6.0 years .	3res
Positive results of this trial will support a paradigm shift in attention to nutrition of all females of child-bearing age .	4con
Suspected malaria-related fever was defined as an axillary temperature > 37.5 C and the concomitant administration of an anti-malarial treatment in the absence of parasitological investigation .	2met
Fifty-one subjects finished the study .	3res
To determine the efficacy and cost of OSA management ( diagnosis and therapeutic decision making ) using ( 1 ) PSG for all patients ( PSG arm ) ; ( 2 ) HRP for all patients ( HRP arm ) ; and ( 3 ) HRP for a subsample of patients with high clinical probability of being treated with continuous positive airway pressure ( CPAP ) and PSG for the remainder ( elective HRP arm ) .	1obj

We hypothesize that limited transthoracic echocardiogram ( LTTE ) is a useful tool to guide therapy during the initial phase of resuscitation in trauma patients .

0bac

Children aged 6 to < 36 months and 36 to < 72 months received 0.25 mL and 0.50 mL doses , respectively .

2met

The functional outcome is better in comparison to the that with other treatments and it is a cost-effective treatment .

4con

In the routine acupuncture group , the routine acupuncture technique was adopted at the main acupoints , such as Shangxing ( GV 23 ) , Baihui ( GV 20 ) , Dicang ( ST 4 ) , Quchi ( LI 11 ) , Huantiao ( GB 30 ) and Zusanli ( ST 36 ) , etc. .

2met

Assessments will be conducted prior to ( week 0 ) , mid-way through ( week 6 ) and following the intervention period ( week 12 ) as well as at a four week follow-up ( week 16 ) .

2met

Intention-to-treat and per-protocol analyses showed an improved salivary flow rate by 0.04 ml/15 min ( 95 % CI : -0.49 to 0.58 ml/15 min ) and 0.04 ml/15 min ( 95 % CI : -0.52 to 0.60 ml/15 min ) , respectively , but the differences were not significant .

3res

We recorded the times of treatments in different groups respectively .

2met

Secondary outcome measures include disease activity , quality of life , adherence to treatment , use of the telenursing service , and cost .

2met

Study parameters were recorded at baseline , immediately after treatment , and after 15 weeks .

2met

No improvements in response or disease control rates , PFS , or OS were gained from the addition of mapatumumab .

3res

A moderate iron chelation regimen that avoids changes in systemic iron levels may constitute a novel therapeutic modality for PD .

2met

Institutional experience substantially influences survival in locally advanced HNC .

4con

Median percent reduction was -28.7 % for placebo , -38.2 % ( P = 0.08 vs placebo ) for once-daily SPN-804 1200 mg , and -42.9 % ( P = 0.003 ) for SPN-804 2400 mg .

3res

Three months postoperatively , the mean reduction in corneal astigmatism was 0.67 diopter ( D ) 0.58 ( SD ) in the toric group and 0.18 0.52 D in the nontoric-OCCI group .

3res

The culture in many team sports involves consumption of large amounts of alcohol after training/competition .

0bac

This learning attenuation diminished during the following learning sessions .

3res

Thus , the advantage of HIIT with regard to time efficiency seems debatable when considering transient HIIT-induced impairments of neuromuscular function .

4con

The prevalence of PFO ( 32 % ) was similar to that reported in low-altitude populations and was not different in participants with and without chronic mountain sickness .

3res

Univariate and multivariate ordinal regression analyses were performed to identify predictors of symptomatic and asymptomatic ICAS based on clinical , laboratory and radiologic data .

2met

To examine adherence to , satisfaction with , and preliminary efficacy of mobile phone short message service ( SMS ) to promote health behaviors in school-aged children .

1obj

As far as is known to the authors , this is the first health economic evaluation of a health promotion intervention targeting physical activity and healthy eating in individuals with mental disorders .

4con

The percentage of patients with PTS in the SM group ranged from 14.9 % ( 1 year after the end of anticoagulation ) to 19.5 % ( 60 months ) .

3res

Individuals treated with VEN-XR had more severe withdrawal-like symptoms , which mediated their continued marijuana smoking .

4con

IMNs and OAR were contoured in 68 planning CT scans .

2met

Subjects were assessed with measures of nicotine and gambling severity and followed for 3 months after treatment .

2met

The comparative analysis of strain-lines pattern suggests that the enhancement of LV function is achieved by a more synchronous recruitment of both left - and right-handed helical fibers .

3res

526 participants with IA will be recruited from British Columbia , Alberta , and Ontario in Canada .

2met

Common clinical practice recommends dual antiplatelet therapy ( DAPT ) for transcatheter aortic valve implantation ( TAVI ) .

0bac

Gloves were tested by the water leak test .

2met

Sensitivity , specificity , and positive predictive value ( PPV ) were calculated relative to two outcomes : cancer status and consensus of three experts about recall .

2met

Similarly , no treatment differences in muscle protein-bound L - [ 1 - ( 13 ) C ] - phenylalanine enrichments were observed at 120 min ( 0.003 0.001 vs. 0.002 0.001 ) or 300 min ( 0.015 0.002 vs. 0.016 0.002 mole percent excess ) after Cas + Serum vs. Cas .

3res

About one half of those who develop adult-onset moyamoya disease experience intracranial hemorrhage .

1obj

Complication rates and NAC outcomes ( tumor size changes , 2-year disease-free survival rate , and 2-year overall survival rate ) were compared between the two groups .

2met

ATT estimates adjusting for this were 6.2 % ( 95 % CI -1.6 to 14.0 ) and 10.4 % ( 95 % CI 2.2 to 18.5 ) , respectively .

3res

Adverse events and neurologic test data were reported .

2met

Alogliptin efficacy was sustained over 2 years in patients with inadequate glycaemic control on metformin alone .

4con

SSI developed in 2 of 100 patients ( 2 % ) in the antibiotic prophylaxis group and 13 of 100 patients ( 13 % ) in the placebo group , indicating a significant difference between the 2 groups ( relative risk ratio , 0.25 ; 95 % confidence interval , 0.070 to 0.92 ; P = .003 ) .

3res

Moreover , in the same group a statistically significant disc shrinkage was shown by IDVA in sixth months of follow-up ( p < 0.05 ) .

3res

Descriptive laboratory study .

2met

No support was found for improved efficacy or support .

3res

The aim of this study was to evaluate factors associated with weight gain among breast cancer survivors prior to enrolling into a behavioral weight loss intervention .

1obj

A prophylactic fixed rate infusion regimen may not improve hemodynamic control ; a variable rate regimen adjusted in response to changes in arterial blood pressure and heart rate may allow more accurate maintenance of baseline blood pressure .

0bac

Comparable mipomersen post-distribution phase plasma concentrations were observed across the 3 dose regimens suggesting similar tissue exposure .

3res

Primary stability of the TADs as measured by placement torque , amount of tooth movement , and age of the patients did not influence displacement of the TADs .

3res

Older age , prior hemorrhage , prior stroke or transient ischemic attack , diabetes , lower creatinine clearance , decreased hematocrit , aspirin therapy , and nonsteroidal anti-inflammatory drugs were independently associated with an increased risk .

3res

This randomised controlled trial will evaluate the effectiveness of an education program on knowledge , self-care and health-related quality of life of Thai HF patients and their carers .

2met

The aim of our study was to compare the effect of oral clonidine and 1/V fentanyl with oral placebo and I/V fentanyl in attenuating the haemodynamic responses to laryngoscopy and intubation in known hypertensive patients .

0bac

Compared to Group D , the heart rate and rate pressure product were significantly lower in Groups M1-M3 .

3res

Fluvoxamine appears to be less effective than citalopram ( p = 0.036 ) , paroxetine ( p = 0.037 ) , clomipramine ( p = 0.05 ) , sertraline ( p = 0.011 ) , and duloxetine ( p = 0.024 ) .

3res

Five patients in the cidofovir group and seven in the imiquimod group either withdrew or were lost to follow-up before the first 6-week safety assessment .

3res

The aim of the extension study was to evaluate different timings for heterologous AS03A-adjuvanted booster vaccination ( A/Indonesia/5 / 2005 ; clade 2.1 ) given at Month 6 , 12 , or 36 post-primary vaccination .

2met

Unique identifier : NCT 01065532 .

0bac

However , there is no sufficient evidence obtained from randomized controlled trials to confirm the role of De Qi in the treatment of acupuncture for tinnitus .

0bac

Patients 12 years old with partial-onset seizures despite treatment with 1-3 antiepileptic drugs at baseline completed a perampanel phase III trial and entered extension study 307 ( NCT00735397 ) .

2met

Short periods of muscle disuse , due to illness or injury , result in substantial skeletal muscle atrophy .

1obj

There was no change in visual acuity between pre - and post-treatment measurements among the study groups .

3res

Both groups completed 3 training sessions per week .

2met

Merck KGaA , Darmstadt , Germany .

0bac

There were no significant differences in total time of assisted ventilation and duration of oxygen therapy between the two groups ( P > 0.05 ) .

3res

No differences in fetal measurements at 36 wk of gestation were observed between the groups , except for body weight and its increment from 23 to 36 wk , which were higher in the supplemented group ( 6.8 % , P = 0.014 and 10.5 % , P = 0.07 , respectively ) .

3res

An anticholinergic agent or antidiuretic agent as an add-on therapy in men previously treated with an alpha-blocker improves nocturia including LUTS .

4con

Nondiabetic pseudophakic patients with definite POAG were recruited ; 29 eyes of 16 individuals participated in study 1 .

2met

Within the first and second periods , the body weight of the patients was observed an increase of 0.4 and 1.6 kg with once-daily dose , whereas a decrease of 0.1 and 2.1 kg in the twice-daily dose , in the same period .

3res

Other assessments included , Clinical Global Impression-Severity ( CGI-S ) , Global Assessment of Functioning ( GAF ) , and Drug-Induced Extrapyramidal Symptoms Scale ( DIEPSS ) .

2met

The operating properties of 2 - and 3-item PRO were evaluated using data from a trial of methotrexate in CD .

2met

This trial was registered at clinicaltrials.gov as NCT01655901 .

4con

Crushing ER OC/APAP further delayed onset of subjective effects compared with intact ER OC/APAP .

4con

In the absence of a definitive `` gold standard '' for the judgement , it is desirable to try and bring novice professionals ' judgemental risk thresholds to the level of competent professionals as quickly and effectively as possible .

0bac

The levels of LPS , TNF-alpha , and IL-6 were lower in the TM group than in the control group at post-operative 96 h ( P < 0.05 ) .

3res

Morphine seems to be more effective at 2 and 4 hours , but after 4 hours they have similar effects , the satisfaction difference between both groups was not significant in the patients .

4con

Participants lost approximately 4.7 2.2 kg ( p < 0.001 ) .

3res

The implants were restored with screw-retained single crowns after 4 months .

2met

No vaccine-related serious adverse events were reported .

3res

RCO resulted in a markedly increased pressor response in HF relative to controls , due primarily to an increase of SBP and attenuated cardiac recovery as noted by the persistent elevation in HR .

4con

Intervention group : The doses of erythropoietin , iron , and vitamin C were adjusted every month based on the ferritin and hemoglobin ( Hb ) levels according to the protocol .

2met

A 6-month aerobic and resistance training exercise regimen was implemented to examine interrelationships between circulating sex hormones , body composition , aerobic capacity , insulin sensitivity , and insulin resistance .

1obj

The trial is registered with ClinicalTrials.gov NCT00757159 .

4con

The median age was 68 , and the median follow-up time was 6.0 years .

3res

Positive results of this trial will support a paradigm shift in attention to nutrition of all females of child-bearing age .

4con

Suspected malaria-related fever was defined as an axillary temperature > 37.5 C and the concomitant administration of an anti-malarial treatment in the absence of parasitological investigation .

2met

Fifty-one subjects finished the study .

3res

To determine the efficacy and cost of OSA management ( diagnosis and therapeutic decision making ) using ( 1 ) PSG for all patients ( PSG arm ) ; ( 2 ) HRP for all patients ( HRP arm ) ; and ( 3 ) HRP for a subsample of patients with high clinical probability of being treated with continuous positive airway pressure ( CPAP ) and PSG for the remainder ( elective HRP arm ) .

1obj