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The AOMP test sites fell within three categories : normal-appearing cones ( N ) , dimly reflecting cones ( D ) , and RPE cell mosaics ( R ) .
3res
Optimal starting point for antiretroviral treatment ( ART ) has been uncertain .
0bac
Improvements in MADRS total score , CGI-S , CGI-I , and HAMD in the olanzapine group were significantly greater relative to those in the placebo group during the 8-week follow-up period ( p < 0.001 , p = 0.0017 , p = 0.007 , and p < 0.001 , respectively ) .
3res
We tested whether there is an association between perceived campus drinking norms and usual drinking behavior in UK university students and whether norm messages about responsible drinking correct normative misperceptions and increase students ' intentions to drink responsibly .
1obj
Participants also reported therapeutic benefits related to self-expression for catharsis , nonjudgmental disclosure , and in-the-moment support .
3res
In women from the general population , the area under the curve of waist circumference was significantly higher than that of the body adiposity index .
3res
This study is a single-blinded , randomized controlled effectiveness trial in which pregnant women were assigned to receive usual care or up to 5 face-to-face brief motivational enhancement sessions lasting 10-30 minutes each and occurring at study enrollment , 4 and 8 weeks after enrollment , 32 weeks of gestation , and 6 weeks postpartum .
2met
Incubators are the gold standard for long-term support and have been adopted successfully in many countries .
0bac
Thirty patients of chronic stable angina pectoris met the inclusive criteria were randomized into an acupuncture group ( 15 cases ) and a medication group ( 15 cases ) , and a healthy control group ( 15 cases of the same ages ) was set up separately .
2met
The control group learned without background music while the 4 experimental groups were exposed to vocal or instrumental musical pieces during learning with different subjective intensity and valence .
2met
In the acupuncture group , acupuncture therapy of promoting the circulation of the Governor Vessel and regulating mentality was applied at Yaoyangguan ( GV 3 ) , Mingmen ( GV 4 ) , Zhiyang ( GV 9 ) , Shenzhu ( GV 12 ) , Dazhui ( GV 14 ) , Yamen ( GV 15 ) , Fengfu ( GV 16 ) , Baihui ( GV 20 ) and Neck-Jiaji ( EX-B 2 ) .
2met
ISRCTN92166560 .
0bac
LGE of 15 % of LV mass demonstrated a 2-fold increase in SCD event risk in those patients otherwise considered to be at lower risk , with an estimated likelihood for SCD events of 6 % at 5 years .
3res
We used a computer generated randomisation list with randomly varying block sizes .
2met
( 2 ) At the end of treatment , the integrals of clinical symptoms decreased in the 3 groups when compared with before treatment in the same group ( P < 0.05 , P < 0.01 ) .
3res
Changes in the Banff score provided significant difference regarding tubulitis and interstitial inflammation ( P = .05 ) .
3res
Treatment was performed during three consecutive years .
2met
The formulations are bioequivalent regarding both rate and extent of absorption .
4con
An electromagnetic motion capture system was used to measure three-dimensional lumbar spine angles that were normalized to maximum active range of motion-a transmitter and receiver were affixed to the skin overlying the lateral aspect of the pelvis and the spinous process of the twelfth thoracic vertebra , respectively .
2met
Merck Sharp and Dohme .
0bac
Four estimates of white matter integrity ( fractional anisotropy [ FA ] and mean [ MD ] , radial [ RD ] , and axial [ AD ] diffusivity ) for 48 white matter tracts throughout the brain were obtained through diffusion tensor imaging .
2met
LVEF was decreased along with the prolongation of chemotherapy in the experimental group and control group .
3res
There were no notable differences in mortality and serious AEs incidence .
4con
The pharmacokinetics of raltegravir ( RAL ) in HIV patients is characterized by high interindividual and intraindividual variability .
0bac
Takeda Development Center Americas .
0bac
Double-blind , cluster randomized , double-crossover trial conducted in 4 ICUs in New Zealand from April 2014 through October 2014 .
2met
NTC also resulted in comparable results for both the response rates of the other evaluation points and incidence of adverse events compared to those of onabotulinumtoxin A.
3res
We investigated the cardioprotective effect of high-dose intragraft adenosine infusion , compared with placebo , on microvascular function and prevention of no-reflow during SVGs intervention .
1obj
This could result in reduced costs and a reduced risk of adverse reactions , without an impact on patient comfort .
4con
Short-segment U-shaped pedicle screw fixation has been widely used to treat thoracolumbar burst fracture .
0bac
To determine the effects of steady-state concentrations of the selective S1P1 receptor modulator ponesimod on the pharmacokinetics ( PK ) of a single dose of a combined oral contraceptive , containing 1mg norethisterone ( NET ) and 35g ethinyl estradiol ( EE ) and to investigate the effects on heart rate at different ponesimod doses within an up-titration regimen prior to co-administration of the contraceptive .
1obj
This randomised-control trial will be undertaken utilising the principles of kaupapa Maaori research , which encompasses Maaori leadership , Maaori relationships , Maaori customary practices , etiquette and protocol .
2met
Clinical assessments were evaluated by NCI-CTC 4.0 grading and patient self-reported pain .
2met
The study included 24 patients who were at the finishing stage of orthodontic treatment and had at least 1 maxillary incisor with 30 to 70 of rotation before starting therapy .
2met
P-OM3-induced changes in eicosapentaenoic acid within low-density lipoproteins and very low-density lipoproteins were associated with beneficial effects on mean arterial pressure and pulse pressure .
3res
Renal impairment in cancer patients can affect treatment tolerability and outcomes .
0bac
We also tested whether the intervention effect was moderated by parent gender , child gender , or child age .
1obj
There were large variations concerning mode of CV used , ECV being heterogeneous .
3res
After 2 weeks the 8-hour studies were repeated on-therapy .
2met
All adverse events were recorded .
2met
Four hundred twenty-three patients were randomized to tadalafil OaD ( N = 139 ) , tadalafil PRN ( N = 143 ) , and placebo ( N = 141 ) .
3res
Sixty-one patients who underwent ND with primary head and neck cancer ( HNSCC ) resection were enrolled in this study and were randomized into two homogeneous groups : CH ( conventional haemostasis with classic technique of tying and knots , resorbable ligature , and bipolar diathermy ) and HS ( haemostasis with harmonic scalpel ) .
2met
To define protein molecular characteristics of tumor cells prior to , and immediately following , preoperative human epidermal growth factor receptor 2 ( HER2 ) - targeted therapy that correlate with pathologic complete response ( pCR ) or non response ( no pCR ) to preoperative HER2-directed therapy and chemotherapy .
0bac
All participants received standard physiotherapy .
2met
Depression and anxiety are prevalent in patients with chronic pain and adversely affect pain , quality of life , and treatment response .
1obj
The role of nutrition in the treatment of attention-deficit hyperactivity disorder ( ADHD ) is gaining international attention ; however , treatments have generally focused only on diet restriction or supplementing with one nutrient at a time .
0bac
Dentocult SM Strip mutans ( D-SM ) strips were used to test the mutans streptococci in saliva .
2met
The greater number of mainly generic oral anti-diabetic agents in the standard group partially offset the higher cost of basal insulin glargine .
3res
Individuals ( N = 964 ) with T2DM , glycosylated hemoglobin ( HbA1c ) of 7.0 % to 10.0 % , and documented CVD .
2met
An intention-to-treat analysis of adjusted effect size ( ES ) was applied .
2met
Similar improvements were seen during 12 weeks of treatment .
3res
Deaths as competing risks were adjusted using Fine-Gray regression and joint models of hospitalizations and mortality .
3res
Consenting participants will be stratified for the presence of subsyndromal symptoms of depression and then randomly assigned to the intervention or control group .
2met
Teachers from six universities were randomly sampled in Shenyang .
2met
( 3 ) Do therapy dogs have an effect on patients ' satisfaction with their hospital stay after total joint arthroplasty as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems ( HCAHPS ) ?
1obj
The frequency of desaturations , episode severity or number of FiO2 adjustments did not differ between the two care strategies .
3res
Linear regression analysis was used to investigate the independent cross-sectional and longitudinal associations of sedentary time with markers of inflammation .
3res
In the treatment of atopic dermatitis , pimecrolimus has high antipruritic effects .
0bac
An 8-week , open-label , randomised controlled trial in rural , primary care in the west of Ireland .
2met
The doubling time of SIgA level was the 3rd d in immunoglobulin group , and the 5th d in control group .
3res
Fifty-five single nucleotide polymorphisms ( SNPs ) covering the variation in 5 CHRNs ( CHRNA4 , CHRNB2 , CHRNA2 , CHRNB3A6 , and CHRNA5A3B4 ) were studied .
2met
This was an 8-week , randomized , double-blind , placebo-controlled clinical trial .
2met
Rates of ovulation , pregnancy , and abortion were compared between both groups .
2met
Median percent reduction from baseline in focal seizure frequency/week was 30.0 % ( p = 0.019 ) , 26.8 % ( p = 0.092 ) , and 32.5 % ( p = 0.004 ) for BRV 20 , 50 , and 100 mg/day , respectively , compared with 17.0 % for PBO .
3res
Differences in DT were an important confounder .
3res
Kinesio Taping is a promising additional approach to increase proprioceptive feedback and improve physical fitness , gross motor function , and activities of daily living in children with CP .
4con
We do not recommend trabectedin discontinuation in patients with advanced , doxorubicin-refractory soft-tissue sarcoma who have not progressed after six cycles of treatment .
4con
The average plasma Lp-PLA2 concentration [ Lp-PLA2 ( V/V ) : 129.4 ng/mL , Lp-PLA2 ( V/F ) : 70.7 ng/mL , Lp-PLA2 ( F/F ) : 0.4 ng/mL ] and activity [ Lp-PLA2 ( V/V ) : 164.3 nmol/min/mL , LpPLA2 ( V/F ) : 100.9 nmol/min/mL , Lp-PLA2 ( F/F ) : 11.6 nmol/min/mL ] were significantly different between each genotype , although the basic clinical characteristics were similar .
3res
The primary efficacy end point was a response on the ACR 20 % , improvement criteria at 24 weeks , Secondary end points were responses on the ACR 50 and ACR 70 , improvement criteria , the DAS 28 , and EULAR response criteria at 24 weeks .
2met
The aim of this open , observational registry was to evaluate the effects of antithrombotic treatment on the development of postthrombotic syndrome ( PTS ) : the effects of `` standard management '' ( SM ; according to International Union of Angiology guidelines ) were compared to SM in association with sulodexide or aspirin .
1obj
Dutch Trial Register NTR2624 .
0bac
However , rhBNP treatment showed no advantages over dobutamine when plasma BNP reached extremely high levels ( > 3000 pg/mL ) .
4con
Six and 12 months after delivery , the women received home visits for anthropometric measures .
2met
Secondary outcomes include indicators of clinical effectiveness of screening at each screening site ( primary and secondary ) including gestational week at time of screening , time to access antenatal diabetes services for women diagnosed with GDM , and pregnancy and neonatal outcomes for women with GDM .
2met
Common facilitators of sit-stand workstation use were a supportive work environment conducive to standing , perceived physical health benefits , and perceived work benefits .
3res
cerebrovascular disease or at least two CVD risk factors .
2met
INTERVENTIONS FOR CLINICAL TRIALS : Patients were randomly assigned to receive clobetasol propionate , 0.05 % cream , or hydrocortisone , 1 % , cream .
2met
Dietary advice to change dairy food has a minor effect on plasma fatty acid levels .
4con
Fourteen participants with a recent motor complete spinal cord injury were consecutively recruited from two spinal cord injury units in Sydney .
2met
Additionally , differences in the efficacy among high - and low-educated people will be examined .
4con
Both classroom teachers and school nurses are effective in conveying reproductive health information to high school students ; however , teaching the technical ( eg , condom use ) and interpersonal ( eg , negotiation ) skills needed to reduce high-risk sexual behavior may require a unique set of skills and experiences that health education teachers may not typically have .
4con
We present our initial experience in a prospective , randomized , single blinded pilot study utilizing this FDA approved system .
0bac
Gender and ethnic differences in eating behaviour were investigated .
2met
Examine the effect of an early intervention programme on cognitive outcome at 7 and 9years in children with birth weight ( BW ) < 2000g .
1obj
Data analysis included 27 subjects on the Korean diet periods and 29 in the DGA and typical American diet periods .
2met
Underestimation of self-reported weights increased significantly from 6 months ( mean -0.5 kg , SD 1.0 kg ) to 24 months ( mean -1.1 kg , SD 2.0 kg ; P = .002 ) .
3res
C had no measurable activity in the first 14 days of treatment .
4con
The dose was adjusted to achieve testosterone levels between 500 and 900 ng/dL .
2met
Height velocity and standard deviation ( SD ) score ; levels of insulin-like growth factor 1 ( IGF-1 ) , osteocalcin ( OC ) , and C-telopeptide of type I collagen ( CTX-I ) ; and Juvenile Arthritis Disease Activity Score in 71 joints ( JADAS-71 ) were measured in a post hoc analysis of 83 patients who never received growth hormone and did not reach Tanner stage 5 by the end of the first year of treatment .
2met
An elevated heart rate is an established marker of cardiovascular risk .
0bac
Stroke is a devastating complication of coronary artery bypass grafting ( CABG ) .
0bac
The results of the present study indicate that a 5-week neck strengthening program improves isometric neck strength in rugby union players , which may have implications for injury prevention , screening , and rehabilitation .
4con
RAI was present in 34 ( 76 % ) patients .
3res
To investigate the safety , pharmacokinetics , and pharmacodynamics of EP42675 and its interaction with aspirin , clopidogrel , and unfractionated heparin ( UFH ) .
1obj
At the end line , median ( IQR ) nutrient densities were significantly higher in the CFR group than in the non-CFR group for iron [ i.e. , 0.6 mg/100 kcal ( 0.4-0 .8 mg/100 kcal ) compared with 0.5 mg/100 kcal ( 0.4-0 .7 mg/100 kcal ) ] and niacin [ i.e. , 0.8 mg/100 kcal ( 0.5-1 .0 mg/100 kcal ) compared with 0.6 mg/100 kcal ( 0.4-0 .8 mg/100 kcal ) ] .
3res
Beginning in 1997 , a total of 14,641 US male physicians aged 50 y were randomly assigned to receive 400 IU of vitamin E every other day , 500 mg of vitamin C daily , or their respective placebos .
2met
Analysis populations for the primary and key secondary endpoints were per-protocol sets .
2met
The patients in experimental group were given `` ingested antirotavirus IgY '' .
2met
Endometrial safety was evaluated in a development program of six randomized , double-blind , placebo-controlled , parallel-group studies of postmenopausal women aged between 40 and 80 years who had vulvar and vaginal atrophy .
2met
To investigate the efficacy and safety of a bilayer combination oxycodone ( OC ) and acetaminophen ( APAP ) analgesic with both immediate-release and extended-release ( ER ) components ( OC/APAP ER ) in patients with moderate to severe pain using an established acute pain model .
1obj