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The AOMP test sites fell within three categories : normal-appearing cones ( N ) , dimly reflecting cones ( D ) , and RPE cell mosaics ( R ) . | 3res
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Optimal starting point for antiretroviral treatment ( ART ) has been uncertain . | 0bac
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Improvements in MADRS total score , CGI-S , CGI-I , and HAMD in the olanzapine group were significantly greater relative to those in the placebo group during the 8-week follow-up period ( p < 0.001 , p = 0.0017 , p = 0.007 , and p < 0.001 , respectively ) . | 3res
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We tested whether there is an association between perceived campus drinking norms and usual drinking behavior in UK university students and whether norm messages about responsible drinking correct normative misperceptions and increase students ' intentions to drink responsibly . | 1obj
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Participants also reported therapeutic benefits related to self-expression for catharsis , nonjudgmental disclosure , and in-the-moment support . | 3res
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In women from the general population , the area under the curve of waist circumference was significantly higher than that of the body adiposity index . | 3res
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This study is a single-blinded , randomized controlled effectiveness trial in which pregnant women were assigned to receive usual care or up to 5 face-to-face brief motivational enhancement sessions lasting 10-30 minutes each and occurring at study enrollment , 4 and 8 weeks after enrollment , 32 weeks of gestation , and 6 weeks postpartum . | 2met
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Incubators are the gold standard for long-term support and have been adopted successfully in many countries . | 0bac
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Thirty patients of chronic stable angina pectoris met the inclusive criteria were randomized into an acupuncture group ( 15 cases ) and a medication group ( 15 cases ) , and a healthy control group ( 15 cases of the same ages ) was set up separately . | 2met
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The control group learned without background music while the 4 experimental groups were exposed to vocal or instrumental musical pieces during learning with different subjective intensity and valence . | 2met
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In the acupuncture group , acupuncture therapy of promoting the circulation of the Governor Vessel and regulating mentality was applied at Yaoyangguan ( GV 3 ) , Mingmen ( GV 4 ) , Zhiyang ( GV 9 ) , Shenzhu ( GV 12 ) , Dazhui ( GV 14 ) , Yamen ( GV 15 ) , Fengfu ( GV 16 ) , Baihui ( GV 20 ) and Neck-Jiaji ( EX-B 2 ) . | 2met
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ISRCTN92166560 . | 0bac
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LGE of 15 % of LV mass demonstrated a 2-fold increase in SCD event risk in those patients otherwise considered to be at lower risk , with an estimated likelihood for SCD events of 6 % at 5 years . | 3res
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We used a computer generated randomisation list with randomly varying block sizes . | 2met
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( 2 ) At the end of treatment , the integrals of clinical symptoms decreased in the 3 groups when compared with before treatment in the same group ( P < 0.05 , P < 0.01 ) . | 3res
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Changes in the Banff score provided significant difference regarding tubulitis and interstitial inflammation ( P = .05 ) . | 3res
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Treatment was performed during three consecutive years . | 2met
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The formulations are bioequivalent regarding both rate and extent of absorption . | 4con
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An electromagnetic motion capture system was used to measure three-dimensional lumbar spine angles that were normalized to maximum active range of motion-a transmitter and receiver were affixed to the skin overlying the lateral aspect of the pelvis and the spinous process of the twelfth thoracic vertebra , respectively . | 2met
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Merck Sharp and Dohme . | 0bac
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Four estimates of white matter integrity ( fractional anisotropy [ FA ] and mean [ MD ] , radial [ RD ] , and axial [ AD ] diffusivity ) for 48 white matter tracts throughout the brain were obtained through diffusion tensor imaging . | 2met
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LVEF was decreased along with the prolongation of chemotherapy in the experimental group and control group . | 3res
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There were no notable differences in mortality and serious AEs incidence . | 4con
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The pharmacokinetics of raltegravir ( RAL ) in HIV patients is characterized by high interindividual and intraindividual variability . | 0bac
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Takeda Development Center Americas . | 0bac
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Double-blind , cluster randomized , double-crossover trial conducted in 4 ICUs in New Zealand from April 2014 through October 2014 . | 2met
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NTC also resulted in comparable results for both the response rates of the other evaluation points and incidence of adverse events compared to those of onabotulinumtoxin A. | 3res
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We investigated the cardioprotective effect of high-dose intragraft adenosine infusion , compared with placebo , on microvascular function and prevention of no-reflow during SVGs intervention . | 1obj
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This could result in reduced costs and a reduced risk of adverse reactions , without an impact on patient comfort . | 4con
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Short-segment U-shaped pedicle screw fixation has been widely used to treat thoracolumbar burst fracture . | 0bac
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To determine the effects of steady-state concentrations of the selective S1P1 receptor modulator ponesimod on the pharmacokinetics ( PK ) of a single dose of a combined oral contraceptive , containing 1mg norethisterone ( NET ) and 35g ethinyl estradiol ( EE ) and to investigate the effects on heart rate at different ponesimod doses within an up-titration regimen prior to co-administration of the contraceptive . | 1obj
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This randomised-control trial will be undertaken utilising the principles of kaupapa Maaori research , which encompasses Maaori leadership , Maaori relationships , Maaori customary practices , etiquette and protocol . | 2met
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Clinical assessments were evaluated by NCI-CTC 4.0 grading and patient self-reported pain . | 2met
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The study included 24 patients who were at the finishing stage of orthodontic treatment and had at least 1 maxillary incisor with 30 to 70 of rotation before starting therapy . | 2met
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P-OM3-induced changes in eicosapentaenoic acid within low-density lipoproteins and very low-density lipoproteins were associated with beneficial effects on mean arterial pressure and pulse pressure . | 3res
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Renal impairment in cancer patients can affect treatment tolerability and outcomes . | 0bac
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We also tested whether the intervention effect was moderated by parent gender , child gender , or child age . | 1obj
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There were large variations concerning mode of CV used , ECV being heterogeneous . | 3res
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After 2 weeks the 8-hour studies were repeated on-therapy . | 2met
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All adverse events were recorded . | 2met
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Four hundred twenty-three patients were randomized to tadalafil OaD ( N = 139 ) , tadalafil PRN ( N = 143 ) , and placebo ( N = 141 ) . | 3res
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Sixty-one patients who underwent ND with primary head and neck cancer ( HNSCC ) resection were enrolled in this study and were randomized into two homogeneous groups : CH ( conventional haemostasis with classic technique of tying and knots , resorbable ligature , and bipolar diathermy ) and HS ( haemostasis with harmonic scalpel ) . | 2met
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To define protein molecular characteristics of tumor cells prior to , and immediately following , preoperative human epidermal growth factor receptor 2 ( HER2 ) - targeted therapy that correlate with pathologic complete response ( pCR ) or non response ( no pCR ) to preoperative HER2-directed therapy and chemotherapy . | 0bac
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All participants received standard physiotherapy . | 2met
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Depression and anxiety are prevalent in patients with chronic pain and adversely affect pain , quality of life , and treatment response . | 1obj
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The role of nutrition in the treatment of attention-deficit hyperactivity disorder ( ADHD ) is gaining international attention ; however , treatments have generally focused only on diet restriction or supplementing with one nutrient at a time . | 0bac
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Dentocult SM Strip mutans ( D-SM ) strips were used to test the mutans streptococci in saliva . | 2met
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The greater number of mainly generic oral anti-diabetic agents in the standard group partially offset the higher cost of basal insulin glargine . | 3res
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Individuals ( N = 964 ) with T2DM , glycosylated hemoglobin ( HbA1c ) of 7.0 % to 10.0 % , and documented CVD . | 2met
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An intention-to-treat analysis of adjusted effect size ( ES ) was applied . | 2met
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Similar improvements were seen during 12 weeks of treatment . | 3res
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Deaths as competing risks were adjusted using Fine-Gray regression and joint models of hospitalizations and mortality . | 3res
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Consenting participants will be stratified for the presence of subsyndromal symptoms of depression and then randomly assigned to the intervention or control group . | 2met
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Teachers from six universities were randomly sampled in Shenyang . | 2met
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( 3 ) Do therapy dogs have an effect on patients ' satisfaction with their hospital stay after total joint arthroplasty as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems ( HCAHPS ) ? | 1obj
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The frequency of desaturations , episode severity or number of FiO2 adjustments did not differ between the two care strategies . | 3res
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Linear regression analysis was used to investigate the independent cross-sectional and longitudinal associations of sedentary time with markers of inflammation . | 3res
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In the treatment of atopic dermatitis , pimecrolimus has high antipruritic effects . | 0bac
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An 8-week , open-label , randomised controlled trial in rural , primary care in the west of Ireland . | 2met
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The doubling time of SIgA level was the 3rd d in immunoglobulin group , and the 5th d in control group . | 3res
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Fifty-five single nucleotide polymorphisms ( SNPs ) covering the variation in 5 CHRNs ( CHRNA4 , CHRNB2 , CHRNA2 , CHRNB3A6 , and CHRNA5A3B4 ) were studied . | 2met
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This was an 8-week , randomized , double-blind , placebo-controlled clinical trial . | 2met
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Rates of ovulation , pregnancy , and abortion were compared between both groups . | 2met
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Median percent reduction from baseline in focal seizure frequency/week was 30.0 % ( p = 0.019 ) , 26.8 % ( p = 0.092 ) , and 32.5 % ( p = 0.004 ) for BRV 20 , 50 , and 100 mg/day , respectively , compared with 17.0 % for PBO . | 3res
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Differences in DT were an important confounder . | 3res
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Kinesio Taping is a promising additional approach to increase proprioceptive feedback and improve physical fitness , gross motor function , and activities of daily living in children with CP . | 4con
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We do not recommend trabectedin discontinuation in patients with advanced , doxorubicin-refractory soft-tissue sarcoma who have not progressed after six cycles of treatment . | 4con
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The average plasma Lp-PLA2 concentration [ Lp-PLA2 ( V/V ) : 129.4 ng/mL , Lp-PLA2 ( V/F ) : 70.7 ng/mL , Lp-PLA2 ( F/F ) : 0.4 ng/mL ] and activity [ Lp-PLA2 ( V/V ) : 164.3 nmol/min/mL , LpPLA2 ( V/F ) : 100.9 nmol/min/mL , Lp-PLA2 ( F/F ) : 11.6 nmol/min/mL ] were significantly different between each genotype , although the basic clinical characteristics were similar . | 3res
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The primary efficacy end point was a response on the ACR 20 % , improvement criteria at 24 weeks , Secondary end points were responses on the ACR 50 and ACR 70 , improvement criteria , the DAS 28 , and EULAR response criteria at 24 weeks . | 2met
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The aim of this open , observational registry was to evaluate the effects of antithrombotic treatment on the development of postthrombotic syndrome ( PTS ) : the effects of `` standard management '' ( SM ; according to International Union of Angiology guidelines ) were compared to SM in association with sulodexide or aspirin . | 1obj
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Dutch Trial Register NTR2624 . | 0bac
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However , rhBNP treatment showed no advantages over dobutamine when plasma BNP reached extremely high levels ( > 3000 pg/mL ) . | 4con
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Six and 12 months after delivery , the women received home visits for anthropometric measures . | 2met
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Secondary outcomes include indicators of clinical effectiveness of screening at each screening site ( primary and secondary ) including gestational week at time of screening , time to access antenatal diabetes services for women diagnosed with GDM , and pregnancy and neonatal outcomes for women with GDM . | 2met
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Common facilitators of sit-stand workstation use were a supportive work environment conducive to standing , perceived physical health benefits , and perceived work benefits . | 3res
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cerebrovascular disease or at least two CVD risk factors . | 2met
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INTERVENTIONS FOR CLINICAL TRIALS : Patients were randomly assigned to receive clobetasol propionate , 0.05 % cream , or hydrocortisone , 1 % , cream . | 2met
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Dietary advice to change dairy food has a minor effect on plasma fatty acid levels . | 4con
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Fourteen participants with a recent motor complete spinal cord injury were consecutively recruited from two spinal cord injury units in Sydney . | 2met
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Additionally , differences in the efficacy among high - and low-educated people will be examined . | 4con
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Both classroom teachers and school nurses are effective in conveying reproductive health information to high school students ; however , teaching the technical ( eg , condom use ) and interpersonal ( eg , negotiation ) skills needed to reduce high-risk sexual behavior may require a unique set of skills and experiences that health education teachers may not typically have . | 4con
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We present our initial experience in a prospective , randomized , single blinded pilot study utilizing this FDA approved system . | 0bac
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Gender and ethnic differences in eating behaviour were investigated . | 2met
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Examine the effect of an early intervention programme on cognitive outcome at 7 and 9years in children with birth weight ( BW ) < 2000g . | 1obj
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Data analysis included 27 subjects on the Korean diet periods and 29 in the DGA and typical American diet periods . | 2met
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Underestimation of self-reported weights increased significantly from 6 months ( mean -0.5 kg , SD 1.0 kg ) to 24 months ( mean -1.1 kg , SD 2.0 kg ; P = .002 ) . | 3res
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C had no measurable activity in the first 14 days of treatment . | 4con
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The dose was adjusted to achieve testosterone levels between 500 and 900 ng/dL . | 2met
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Height velocity and standard deviation ( SD ) score ; levels of insulin-like growth factor 1 ( IGF-1 ) , osteocalcin ( OC ) , and C-telopeptide of type I collagen ( CTX-I ) ; and Juvenile Arthritis Disease Activity Score in 71 joints ( JADAS-71 ) were measured in a post hoc analysis of 83 patients who never received growth hormone and did not reach Tanner stage 5 by the end of the first year of treatment . | 2met
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An elevated heart rate is an established marker of cardiovascular risk . | 0bac
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Stroke is a devastating complication of coronary artery bypass grafting ( CABG ) . | 0bac
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The results of the present study indicate that a 5-week neck strengthening program improves isometric neck strength in rugby union players , which may have implications for injury prevention , screening , and rehabilitation . | 4con
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RAI was present in 34 ( 76 % ) patients . | 3res
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To investigate the safety , pharmacokinetics , and pharmacodynamics of EP42675 and its interaction with aspirin , clopidogrel , and unfractionated heparin ( UFH ) . | 1obj
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At the end line , median ( IQR ) nutrient densities were significantly higher in the CFR group than in the non-CFR group for iron [ i.e. , 0.6 mg/100 kcal ( 0.4-0 .8 mg/100 kcal ) compared with 0.5 mg/100 kcal ( 0.4-0 .7 mg/100 kcal ) ] and niacin [ i.e. , 0.8 mg/100 kcal ( 0.5-1 .0 mg/100 kcal ) compared with 0.6 mg/100 kcal ( 0.4-0 .8 mg/100 kcal ) ] . | 3res
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Beginning in 1997 , a total of 14,641 US male physicians aged 50 y were randomly assigned to receive 400 IU of vitamin E every other day , 500 mg of vitamin C daily , or their respective placebos . | 2met
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Analysis populations for the primary and key secondary endpoints were per-protocol sets . | 2met
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The patients in experimental group were given `` ingested antirotavirus IgY '' . | 2met
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Endometrial safety was evaluated in a development program of six randomized , double-blind , placebo-controlled , parallel-group studies of postmenopausal women aged between 40 and 80 years who had vulvar and vaginal atrophy . | 2met
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To investigate the efficacy and safety of a bilayer combination oxycodone ( OC ) and acetaminophen ( APAP ) analgesic with both immediate-release and extended-release ( ER ) components ( OC/APAP ER ) in patients with moderate to severe pain using an established acute pain model . | 1obj
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