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For the study , 1,000 with CHB or HBV-related compensated cirrhosis are randomly assigned in a 1:1 ratio to a treatment group ( 0.5 mg ETV once daily ; 2 g RGT three times daily ) or a control group ( 0.5 mg ETV once daily ; 2 g RGT dummy agent three times daily ) . | METHODS |
Biomarkers were measured at randomization in 14798 patients . | RESULTS |
The aim of this study was to evaluate the effects of umbilical cord milking ( UCM ) on the need for packed red blood cell ( PRBC ) transfusion and hematologic and hemodynamic parameters in very-low-birth-weight infants . | OBJECTIVE |
DHA-enriched canola oil exerts anti-inflammatory effects compared with polyunsaturated fatty acids from plant sources . | CONCLUSIONS |
The primary end-point was occurrence of ipsilateral breast tumour recurrences ( IBTRs ) ; the main analysis was by intention-to-treat . | METHODS |
FC seems to increase and remain elevated before clinical or endoscopic relapse , suggesting that it can be used as a surrogate marker for predicting and identifying patients requiring close follow-up in clinical practice . | CONCLUSIONS |
This trial was registered with Clinicaltrials.gov on 10 February 2014 , registration number : NCT02063503 . | BACKGROUND |
We conducted a randomized , blinded crossover study of aldosterone vs vehicle and compared the effects of a low-sodium versus a high-sodium diet . | METHODS |
Nearly 43 % reported CVD-medication nonadherence in the past month . | RESULTS |
When limiting to malignant tumours , the crude ORs were of similar magnitude . | RESULTS |
That of cystatin C-based CIN was 8.1 % : 6.8 % in the saline group , 6.9 % in the oral NAC group , and 10.8 % in the i.v. NAC group ( P = 0.491 ) . | RESULTS |
After a median ( interquartile range ) follow-up period of 5.0 years ( 1.3 years ) , 6 % of the cohort experienced a CVD event ( 12.2 per 1,000 person-years ; 95 % CI 9.3-15 .9 ) . | RESULTS |
Very few meetings between occupational therapist and patient were cancelled . | RESULTS |
Rapid travel over multiple time zones usually results in transient de-synchronization between environmental time and the biological clock of the individual . | BACKGROUND |
Physiologic measurements were collected at baseline and study end . | METHODS |
927 completed all study visits and were included in the primary analysis . | RESULTS |
Postoperative analgesia is important in patients undergoing open abdominal surgery . | BACKGROUND |
Further , the application of Statistical Process Control might enable closer investigation of the cognitive changes after acquired brain injury and demonstrate the usefulness of process measures in rehabilitation . | CONCLUSIONS |
AQX-1125 ( 450 mg daily ) or placebo was administered orally for 7 days . | METHODS |
A slower COP mean velocity ( p = .05 ) , and an increase in overall foot and ankle function ( p < .05 ) were also observed . | RESULTS |
Each participant in the intervention group took one Royal jelly capsule orally per day , starting on the first day of menstruation and continued the same treatment daily throughout two consecutive menstrual cycles , while participants in the intervention group took placebo capsules as same method . | METHODS |
It is therefore important that these disorders are treated adequately . | BACKGROUND |
The severity of nausea was assessed based on the visual analogue scale . | METHODS |
The primary endpoint was the total amount of intraoperative blood loss . | METHODS |
Forty-two patients completed the study ( 24 active , 18 sham ) . | RESULTS |
These scores did not differ significantly . | RESULTS |
Statins have anti-inflammatory and immunomodulatory properties in addition to lipid-lowering effects . | BACKGROUND |
A cost-benefit analysis will also be conducted . | METHODS |
Aromatherapy represents a complementary and alternative therapy for the management of PONV . | BACKGROUND |
At baseline , compared with US subjects , Canadian subjects were more likely to be students ( 19 % vs. 7 % , p < 0.01 ) and to consume alcohol ( 91 % vs. 63 % , p < 0.01 ) . | RESULTS |
The top 5 frequently encountered genera were subjected to antibiotic disk diffusion sensitivity to identify epidemiologically related transmission events . | METHODS |
In addition , rhTPO plus CsA were well tolerated and adverse events recorded were mild . | RESULTS |
Pairwise comparisons of HAMD-17 change with combination therapy versus paroxetine alone demonstrated no significant difference ( p = 0.567 ) . | RESULTS |
Intervention outcomes were assessed at baseline , 6 and 12months based on venue-based pair comparisons . | METHODS |
Plasma ghrelin decreased in comparison with baseline only after patients consumed the LGI-HF and LGI-LF breakfasts ( P 0.05 ) . | RESULTS |
Multi-centre , outcome assessor-blinded , randomized parallel group study . | METHODS |
In a parallel group randomization design , 128 daily cigarette smokers ( 50 % male , 50 % female ) will attend an initial screening session and be assigned plain or branded packs of cigarettes to smoke for a full day . | METHODS |
The median area was 7513 ( 25th-75th percentile [ Q1-Q3 ] 6634-8180 ) if viral load < 50 copies/mL and 7679 ( Q1-Q3 6899-9373 ) if viral load 50 copies/mL ( p-value 0.0284 ) . | CONCLUSIONS |
Secondary parameters such as doses of complementary analgesics and side effects were also recorded . | METHODS |
A total of 199 adults with FM ( mean age 46.1 years , 95 % women ) who were enrolled in a randomized clinical trial wore a hip-mounted accelerometer for 1 week and completed self-report measures of physical function ( Fibromyalgia Impact Questionnaire-Physical Impairment [ FIQ-PI ] , Short Form 36 [ SF-36 ] health survey physical component score [ PCS ] , pain intensity and interference ( Brief Pain Inventory [ BPI ] ) , and depressive symptoms ( Patient Health Questionnaire-8 [ PHQ-8 ] ) as part of their baseline and followup assessments . | METHODS |
Duration of CSE procedure , the number of spinal punctures , dural click feeling and the effects of test dose did not differ between the groups . | RESULTS |
Positive therapeutic suggestions ( TS ) may be given to patients while they are emerging from general anesthesia as a potential tool to decrease distress . | BACKGROUND |
But there were significant reductions of the mean score of fatigue in the experimental group compared to the placebo group immediately , two and four weeks after the intervention respectively ( p = 0.03 , p ? | RESULTS |
We compared the clinical and radiological outcomes for the conventional DHS and locking DHS in intertrochanteric fractures . | METHODS |
The effective concentration of nerve block was calculated by probit analysis . | METHODS |
Long-term data did not indicate new safety concerns with FBT doses up to 800 g. | CONCLUSIONS |
Black individuals with lung cancer ( LC ) experience higher mortality because they present with more advanced disease and are less likely to undergo curative resection for early-stage disease . | BACKGROUND |
ATV plus -3 FAEEs lowered VLDL-TG concentration to a greater degree compared with placebo ( -46 % , p < 0.001 ) or ATV monotherapy ( -13 % , p = 0.04 ) . | RESULTS |
Implementation was locally managed for usual collaborative care and centrally managed for STEPS-UP . | RESULTS |
The effect of acupuncture on six seed-associated networks was explored . | RESULTS |
Low CCr was a significant risk factor for surgical complications in D2 gastrectomy after NAC . | CONCLUSIONS |
In patients presenting with NSTE-ACS and elevated troponin T , GDF-15 provides prognostic information in addition to identified predictors for mortality and spontaneous MI and can be used to identify patients at high risk during long-term follow-up . | CONCLUSIONS |
Symptom severity was assessed by Clinician-Administered PTSD Scale at the beginning of the study and after 2 , 4 , 6 , and 8 weeks . | METHODS |
ISRCTN21676269 . | BACKGROUND |
Results revealed significant effects on most of the outcome parameters for MI + PI ( eg , mean SD BMI z score : 2.58 0.61 ) compared with the passive control group ( 2.76 0.70 ; post hoc test , P = .02 ) , as well as an additional superiority of MI + PI compared with MI only ( 2.81 0.76 ; post hoc test , P = .05 ) . | RESULTS |
Results of this proof-of-concept study revealed that ranolazine improved measures of hemodynamics but that there was no improvement in relaxation parameters . | CONCLUSIONS |
High doses of triptorelin are needed to achieve and maintain complete ovarian suppression , but such doses appear to be well tolerated in adolescent female patients with childhood-onset SLE . | CONCLUSIONS |
The children 's parents in the intervention group received a collective curriculum on children 's anxiety management six times , while the control group was only followed up . | METHODS |
Previous studies have only investigated the length of hospital care immediately related to IPC insertion . | BACKGROUND |
Participants with self-reported epilepsy and subjective complaints of depressive symptoms were randomized to an intervention condition ( Deprexis ) or to a waiting list control ( WLC ) condition . | METHODS |
The EC50 of sevoflurane for laryngeal mask airway placement after OM ( 1.66 0.31 ) and IND ( 1.57 0.14 ) premedications was significantly lower than the placebo group ( 2.00 0.17 , P < 0.0001 ) . | RESULTS |
Ten-day reverse sequential therapy and standard sequential therapy are equally effective for H.Pylori eradication . | CONCLUSIONS |
Operating time was 53.4 12.5 and 44.4 7.2 min in groups A and B , respectively , and the difference was statistically significant ( p < 0.001 ) . | RESULTS |
Data fabrication was suspected . | RESULTS |
To investigate the QT/QTc effects of orally administered moxifloxacin in healthy Chinese volunteers . | OBJECTIVE |
Outcomes ( pain , functional impairment and number of shoulder dislocations sustained ) will be evaluated prior to surgery and , together with participant-reported improvement , again at 6 , 12 and 24 months after randomization . | METHODS |
Pediatric patients with acute lymphoblastic leukemia ( ALL ) are treated with oral 6-mercaptopurine ( 6MP ) for nearly 2 years , but no pediatric formulation has been available . | OBJECTIVE |
Arrhythmias were rare and similar with all treatments . | RESULTS |
During the insomnia intervention period participants will have their depression management coordinated by a psychiatrist using standard guideline-based depression treatments . | METHODS |
In HF , inhaled CO2 and acetazolamide reduce exercise PB with additional benefits of acetazolamide on sleep PB . | CONCLUSIONS |
Taken together , these findings reveal the benefits of glutamine alone or in combination with other gut-trophic nutrients in growing children via interactions with leptin . | CONCLUSIONS |
Enrolled subjects were randomly assigned to a 4 week treatment with lercanidipine 20mg/day or amlodipine 10mg/day . | METHODS |
Stroke was significantly increased in the CABG group ( PCI 1.5 % versus CABG 4.3 % ; hazard ratio , 0.33 [ 95 % confidence interval , 0.12-0 .92 ] ; P = 0.03 ) and repeat revascularization in the PCI arm ( 26.7 % versus 15.5 % ; hazard ratio , 1.82 [ 95 % confidence interval , 1.28-2 .57 ] ; P < 0.01 ) . | RESULTS |
Randomized controlled trial , in which the assessments were performed by the same physiotherapist in two moments : before and after the procedure . | METHODS |
Nine hundred and two survivors provided analysable answers . | METHODS |
To evaluate the efficacy of early video-assisted thoracoscopic debridement in patients with the fibropurulent phase of parapneumonic empyema . | OBJECTIVE |
Hemodynamic variables were monitored . | METHODS |
We evaluated NSD episodes in the INTRINSIC RV Trial and their relationship to ICD shocks ( appropriate and inappropriate ) . | RESULTS |
Individuals involved in the early stages of a passionate romantic relationship can be consumed by the experience and report emotional dependence and constant focus on their romantic partner . | OBJECTIVE |
Furthermore , no significant differences were detected in any subjective appetite sensations ( all P > 0.05 ) . | RESULTS |
Cognitive , receptive and expressive language , and fine and gross motor scores on the Bayley scales of infant development-III ; height , weight , and hemoglobin levels measured at the baseline and end of intervention . | METHODS |
Treatment with 8 weeks of rebamipide plus the first 4 weeks of PPI demonstrated a reduction ratio of artificial ulcers superior to that with 8 weeks of PPI mono-therapy . | CONCLUSIONS |
Both groups follow standard-of-care rehabilitation protocol . | METHODS |
Among children with fever or cough without diarrhea , zinc use was low ( < 0.5 % ) . | RESULTS |
The primary endpoint was the total volume contrast agent used during PCI . | METHODS |
We recruited women aged 18-25 years attending family planning or abortion care visits and not desiring pregnancy in the next 12 months . | METHODS |
Analysis of each subgroup ( 20 and 40 mg ) showed no significant variation in TSH levels before and 3 months after omeprazole treatment ( median levels : 2.24 vs. 2.42 mU/L , p = 0.62 , and 2.28 vs. 2.30 mU/L , p = 0.82 , respectively ) . | RESULTS |
RRA 29 % ( 95 % confidence interval [ 95 % CI ] 15.0-43 .0 % ) , RRR 0.59 ( 95 % CI :0.31 -0.76 ) , and NNT 3.5 ( 95 % CI 2.3-6 .8 ) . | RESULTS |
Children 's ` on-task ' behaviour , enjoyment of mathematics and mathematics attainment will be assessed as secondary outcomes . | METHODS |
Increased activity in the - frequency range ( 8-14 Hz ) was observed emerging and gradually accumulating 10 s before a missed target . | RESULTS |
Currently , early weight-loss predictions of long-term weight-loss success rely on fixed percent-weight-loss thresholds . | BACKGROUND |
However , exploration of higher doses may be warranted . | CONCLUSIONS |
Tested covariates were : Sociodemographics , Health , Treatment , Drug use and illegal activities . | METHODS |
Pictures taken before and after 7 weeks of 5 facial areas ( forehead , nasolabial folds , area above the upper lip , jawline and area under the chin ) were evaluated by a panel of laypersons . | METHODS |
Both treatments produced a significant improvement in expressible meibomian glands compared to the baseline parameters , but no significant difference was noted between the two groups . | RESULTS |
A higher proportion of patients in the ACT arm experienced grade 3 leucopenia ( 0 % in the TU arm , 4 % in the ACT arm ) . | RESULTS |
The head points in cluded Sishencong ( EX-HN 1 ) , Shenting ( GV 24 ) and Benshen ( GB 13 ) . | METHODS |
The other half underwent only light-emitting diode phototherapy . | METHODS |
We randomized 70 patients with severe alcoholic hepatitis . | METHODS |
Increasing rates of obesity and associated diseases and their consequences make the implementation of preventive and counteracting measures necessary . | BACKGROUND |