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Sensory manifestations were assessed in 10 healthy volunteers via a platform of 11 quantitative sensory ( thermal and mechanical stimuli ) and vasomotor tests ( skin temperature , perfusion and axon-reflex-flare ) in a double-blinded randomized crossover design .
METHODS
Results Forced expiratory volume in 1 s ( FEV1 ) of both groups increased obviously 30 min and 3 h after first dosing .
METHODS
Children having an AAP at baseline were almost twice as likely to attend two or more PCP visits over 12 months while controlling for asthma control , group status , child age and number of asthma ED visits .
RESULTS
WBC improves acute recovery during high-intensity intermittent exercise in thermoneutral conditions .
CONCLUSIONS
This post hoc analysis of RECOVER further evaluates the effect of rotigotine on pain , and whether improvements in pain may be attributable to benefits in motor function or sleep disturbance .
BACKGROUND
This 8-week , randomized , double-blind , placebo-controlled study , conducted August 2010-May 2012 in the United States , evaluated the safety and efficacy of vortioxetine 10 mg and 15 mg in patients with major depressive disorder ( MDD ) .
BACKGROUND
The study findings will have significant implications for the delivery of PBS in community based services with the potential for reducing inpatient admissions and out-of-area placements for adults with intellectual disability and challenging behaviour .
CONCLUSIONS
The 2 WBV protocols induced higher RPE than the control condition during static standing exercise only .
RESULTS
Although higher step counts were associated with lower FIQ and BPI pain intensity scores , these were not statistically significant .
RESULTS
After 6 months , the survival rates ( 50 % and 11 % , respectively ) and changes in the tumor were significantly different between the 2 groups ( P < 0.05 ) .
RESULTS
Three trained observers measured BP five times consecutively in the seated position at each of two home visits and one clinic visit according to the guidelines of the European Society of Hypertension .
METHODS
This phase II randomised controlled trial provides substantial evidence for the efficacy of incentives for smoking cessation in pregnancy ; as this was only a single centre trial , incentives should now be tested in different types of pregnancy cessation services and in different parts of the United Kingdom .
CONCLUSIONS
Repeated-measures analysis of variance revealed significant physiologic differences of mean heart rate , respiratory rate , and SaO2 ( F = 41.116 , P < 0.0005 ) and behavioral states ( F = 38.564 , P < 0.0005 ) from baseline to 10 minutes after the M Technique intervention across all 3 time points .
RESULTS
Analyses will be conducted on an intention-to-treat basis .
METHODS
NCT01949038 ClinicalTrials.gov .
BACKGROUND
The trial was closed before completion due to slow recruitment .
RESULTS
In univariate analysis , drug , age and mean size of corneal infiltrate and epithelial defect had a significant effect on the final visual outcome .
RESULTS
Multivariable regression for overall cosmesis found larger specimen volume and reoperation to be predictors of worse ratings .
RESULTS
Intraoral elastics are commonly used in orthodontics and require regular changing to be effective .
BACKGROUND
The authors compared the effectiveness of lung collapse using DLT , BB , and BB with the disconnection technique .
OBJECTIVE
Furthermore , the earlier application , the better results were .
CONCLUSIONS
Ultrasound ( US ) - guided needling with subacromial corticosteroid injection is more effective than extracorporeal shock wave therapy ( ESWT ) for function restoration and pain relief in patients with calcific tendinitis of the shoulder .
OBJECTIVE
Department of Plastic Surgery and Burns Unit , Mayo Hospital , King Edward Medical University , Lahore , from January 2011 to January 2013 .
METHODS
In this pilot study , no incremental benefit for ARC was apparent .
CONCLUSIONS
These findings support the efficacy of individual-ESI compared with group-ESI on child outcomes , suggesting the importance of individualized parent coaching in natural environments .
CONCLUSIONS
Thirty-nine participants were randomized into Group A ( n = 20 ) and Group B ( n = 19 ) .
METHODS
The INSPIRON-I trial is a first-in-man evaluation of the safety and efficacy of the Inspiron drug-eluting stent , a sirolimus-eluting stent with abluminal biodegradable polymer coating and thin cobalt-chromium alloy .
OBJECTIVE
The number of patients with AF at discharge was not different between these two groups ( 10 % on pump , 10 % off pump ) .
RESULTS
However , few studies have assessed whether COPD , a potentially modifiable factor , is associated with an increased risk for MCI and whether the relation is specific to the type of MCI .
OBJECTIVE
Patients were randomized to group 1 ( standard-size ETT , 8.0 mm for men and 7.5 mm for women ; n = 24 ) or group 2 ( small ETT , 7.0 mm for men and 6.5 mm for women ; n = 25 ) .
METHODS
The patients in the accelerated group had better mobility , strength , and DASH scores at the early postoperative time points ( zero to eight weeks postoperatively ) compared with the patients in the standard rehabilitation group .
RESULTS
The intervention group had therapeutic hypothermia to a temperature of 32-33C for 72 hours followed by slow rewarming at a rate compatible with maintaining intracranial pressure and cerebral perfusion pressure .
METHODS
No deaths or vaccine-related serious adverse events were reported throughout the studies .
RESULTS
Knowledge of the skin cancer examination ( SCE ) and its practice remain relevant competency gaps among medical students .
BACKGROUND
At year 3 , 401 ( 80 % ) patients were included in the modified intention-to-treat group .
RESULTS
Researchers face myriad challenges in the design and implementation of randomized , controlled trials .
BACKGROUND
The mean difference in saturation values between the fast and the slow groups was -0.3 ( CI , -1.5 to 0.8 ; P = .55 ) , indicating that no meaningful systematic bias is attributable to fast withdrawal of blood .
RESULTS
The probiotic bacterium Escherichia coli Nissle 1917 ( EcN ) has been used to maintain and induce clinical remission in UC .
OBJECTIVE
A significant treatment condition by responder status interaction for glucocorticoid sensitivity indicated that responders to hydrocortisone augmentation had the highest pre-treatment glucocorticoid sensitivity ( lowest lysozyme IC50-DEX ) that diminished over the course of treatment .
RESULTS
The subjects were divided into groups according to their serum 25-hydroxy vitamin D levels .
METHODS
It is unclear why this may be , but previous experimental studies indicate that observing the body when a noxious stimulus is applied can have an analgesic effect .
CONCLUSIONS
Our results suggest that analysis of the impact of anxiety on depression outcome needs to differentiate psychic and somatic symptoms .
CONCLUSIONS
Even without previous training , students are fast to acquire the necessary skills during surgical internship .
CONCLUSIONS
The verbal numeric rating of pain was lower in the dex group .
RESULTS
Retrograde intrarenal surgery was started using a 7.5 Fr semirigid ureteroscope ( Storz ) and the holmium laser , and completed by the Flex X2 flexible ureterorenoscope .
METHODS
Ten ( 25.6 % ) and 19 ( 25.3 % ) individuals in the HB-HTC and in the MC-HTC arms , respectively , linked to HIV care within 1 mo after testing positive .
RESULTS
The clinical effect was larger in children with more severe asthma exacerbation ( p = 003 ) and those with symptoms present for less than 6 h ( p = 0049 ) .
RESULTS
Similar analyses were conducted with a logistic regression model to predict response rates .
METHODS
The corresponding HRs for amiodarone compared to placebo were 0.68 ( 95 % CI : 0.46 to 1.02 ) for the top , 0.86 ( 95 % CI : 0.61 to 1.21 ) for the middle , and 1.56 ( 95 % CI : 1.17 to 2.09 ) for the bottom tertile .
RESULTS
After 1 year of treatment , remission was achieved in 41.3 % of the J-RAPID and 34.9 % of the HIKARI patients with a week 12 DAS28 ( ESR ) response of 1.2 .
RESULTS
37 of the patients initially allotted to nonsurgical treatment underwent secondary surgery due to significant loss of reduction .
RESULTS
Pregnant women with missed or incomplete miscarriages at gestations up to 14 weeks were recruited in this study .
METHODS
Primary : satisfactory anxiolysis at 30 min after drug administration .
METHODS
Level of inflammation , assessed by interleukin-6 and procalcitonin , was independently associated with increased mortality with the highest discriminative value obtained 24 hours after out-of-hospital cardiac arrest .
CONCLUSIONS
The second outcome was to compare the difference of mechanical pain thresholds in the forearm postoperatively between RD and the HD groups .
METHODS
No complications ( infection , skin atrophy , neurovascular damage , or tendon rupture ) were noted .
RESULTS
Cryptococcal meningitis ( CM ) is a severe AIDS-defining illness with 90-day case mortality as high as 70 % in sub-Saharan Africa , despite treatment .
BACKGROUND
To demonstrate bioequivalence of linagliptin/metformin fixed-dose combination ( FDC ) tablets and the corresponding combination of individual tablets taken together , i.e. , free-pill ( FP ) treatment .
OBJECTIVE
The primary outcomes were intraoperative blood loss and postoperative drainage .
METHODS
We tested whether mediated effects were moderated by severity of baseline symptoms .
BACKGROUND
There was no significant difference between pregabalin and levetiracetam in the percent change in 28-day seizure rate ( median difference [ 95 % CI ] , 4.1 [ -2.6 to 10.9 ] , p = 0.3571 ) .
RESULTS
Patients having PRK were randomized to a senofilcon A ( Acuvue Oasys ) , balafilcon A ( Purevision ) , or lotrafilcon A ( Air Optix ) bandage SCL in each eye postoperatively .
METHODS
From a clinical point of view , the clear relationship between fall-related concerns and ADL dysfunction and social participation may help to target groups who are at risk of developing adverse consequences of concerns about falls .
CONCLUSIONS
T ( 0 ) time point VAS value in group L was lower than at T4 time point and greater than at T ( 6 ) .
RESULTS
Likelihood of cost-effectiveness was calculated using Net Monetary Benefit method .
METHODS
Alcohol-related neurodevelopmental disorder ( ARND ) is not as clearly differentiated from controls .
RESULTS
The purpose of this study was to investigate these and related questions .
OBJECTIVE
Meanwhile , patients in Group B constantly received intact protein enteral nutrition support .
METHODS
Average daily consumption of oxycodone prolonged-release tablets was ( 132.042.2 ) mg and ( 110.733.9 ) mg , respectively , which is lower in treatment group than in control group , and the difference was statistically significant ( P = 0.035 ) .
RESULTS
Feedback that provides reinforcement has the potential to increase dietary self-monitoring and enhance attainment of recommended dietary intake .
BACKGROUND
Intra-operative systematic local infiltration analgesia reduces postoperative pain in patients undergoing vaginal hysterectomy , facilities mobilization and improves early recovery .
CONCLUSIONS
BRS showed a significant group with time interaction ( F = 6.930 ; p = 0.003 ) .
RESULTS
Adverse events occurred with similar frequency across all treatment groups .
RESULTS
The severity of IBS-like symptoms , psychological factors , and its impact on Qol were assessed using questionnaires .
METHODS
Demographic and clinical characteristics as well as the pattern of decrease in PrRPl/B were the same between groups .
RESULTS
Intravenous dexmedetomidine at a dose of 0.3 g/kg can reduce emergence agitation after oral and maxillofacial surgery with safety and efficacy .
CONCLUSIONS
Patients were randomized to weight management ( intervention ) or general lifestyle advice ( control ) .
METHODS
Forty consecutive patients were included , with 20 patients being allocated for each group .
METHODS
Response ( tumor size reduction ) was assessed at Month 6 post-treatment and survival , at Month 60 .
METHODS
Twenty-five patients were enrolled into each group : 5-RTP , 10-RTP , and 20-RTP .
METHODS
Twenty healthy full-term neonates born during the same period were randomly selected as the normal control group .
METHODS
Based on the results of this trial , it is concluded that chronic thoracic pain of non-facet joint origin may be managed conservatively with thoracic interlaminar epidural injections with or without steroids .
CONCLUSIONS
This study examined secondary outcomes from a CBSM intervention trial for women with early-stage breast cancer to test if CBSM would improve sleep quality and fatigue among these patients at a single site in southern Florida .
OBJECTIVE
Mean pretreatment CHIP-CE : PRF T-scores were more than one standard deviation below the normative mean in four of the five domains , and there was significant improvement across all domains from baseline to endpoint of the open-label period .
RESULTS
Restricting cetuximab administration to patients with RAS wild-type tumours will further tailor therapy to maximise benefit .
CONCLUSIONS
The post-operation exhaust and defecation time of patients in the TAES group apparently appeared earlier than those of patients in the control group ( P < 0.01 ) .
RESULTS
For the face and upper extremities , a significantly higher percentage of patients in the combination therapy group achieved repigmentation , and at earlier times ( face , 41.0 vs 61.0 days [ P = .001 ] ; upper extremities , 46.0 vs 69.0 days [ P = .003 ] ) .
RESULTS
An event was defined as an SPI over 50 ( SPI-guided group ) or a blood pressure or heart rate 20 % above the baseline ( control group ) .
METHODS
Fever and parasite clearance and coma resolution time were compared between the two groups .
METHODS
Clinically significant differences in primary or secondary outcomes between the two groups were not detected .
RESULTS
OS was analyzed using an unadjusted log-rank test .
METHODS
After that point , marginal bone levels remained stable over time , up to the 8-year follow-up .
RESULTS
Of the patients who had at least one high-use episode , those in the SMART group had fewer days of high use without medical review ( 85 days [ 178 ] vs 183 days [ 248 ] , 049 [ 031-075 ] ; p = 0001 ) .
RESULTS
Patients treated with 0.2 mg tamsulosin daily without other lower urinary tract symptoms secondary to benign prostatic hyperplasia medication for more than 3months and refractory to this treatment were enrolled .
METHODS
The objective of the study was to estimate the effect of Burch and fascial sling surgery on out-of-pocket urinary incontinence ( UI ) management costs at 24 months postoperatively and identify predictors of change in cost among women enrolled in a randomized trial comparing these procedures .
OBJECTIVE
In group 2 , 28 patients were enrolled for propofol infusion , and seven patients were dropped out before underwent DBE , five due to hemodynamic instability ( n = 5 ) , and two refused treatment ( n = 2 ) .
METHODS
A convenience sample of 100 of these patients with ischemic stroke will be included in BAPTISe and will receive magnetic resonance imaging ( MRI ) scans and an additional blood draw before and after the PHYS-STROKE intervention .
METHODS
ACTRN : ACTRN12613001274763 .
BACKGROUND
The criterion group ( N = 23 ) was formed by girls who received high score in EAQ ( signs of ARS ) in the first stage of research ( N = 189 ) .
METHODS
According to diary records from 32 participants , 59 % carried out at least the recommended practice amount .
RESULTS