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Multicenter randomized controlled trial . | METHODS |
In Europe , the USA and Australia , TDR prevalence rates varied by country . | CONCLUSIONS |
No significant difference in postoperative complications was seen . | RESULTS |
All the data was collected by using a proforma and different parameters were assessed for a minimum follow-up period of three months . | METHODS |
to compare the effects of pulsed electromagnetic field ( PEMF ) therapy and sham treatment on DOMS-related variables in elbow flexors at 24 , 48 and 72 h after delayed onset muscle soreness ( DOMS ) induction exercise . | OBJECTIVE |
Disease activity of all the patients was measured by the Disease Activity Score in 28 joints ( DAS28 ) at baseline , and days 4 and 30 . | METHODS |
At the second interim analysis of overall survival ( 58 % maturity ) , overall survival did not significantly differ between the groups ( HR 088 [ 95 % CI 064-121 ] ; p = 044 ) ; similar findings were noted for patients with mutated BRCA ( HR 073 [ 045-117 ] ; p = 019 ) and wild-type BRCA ( HR 099 [ 063-155 ] ; p = 096 ) . | RESULTS |
This study aimed to assess the effects of sampling interval ( SI ) of computed tomographic ( CT ) perfusion acquisitions on CT perfusion values in normal liver and liver metastases from neuroendocrine tumors . | OBJECTIVE |
The group 3 mean was significantly ( P = .02 ) lower than group 1 . | RESULTS |
Cardiovascular risk factors and self-reported behaviour improved in both groups with no significant differences between groups . | RESULTS |
In the group 2 patients , healing was rated as a success in 42.1 % , an improvement in 31.6 % , and a failure in 26.3 % . | RESULTS |
In the study , 90 adult patients with maxillofacial diseases were divided randomly into control group ( group C ) , flurbiprofen group ( group F ) and dezocine group ( group D ) . | METHODS |
The apolipoprotein A-I/apolipoprotein B ratio increased only in the atazanavir/ritonavir arm . | RESULTS |
The UL efficacy of daily febuxostat 80mg was greater than that of febuxostat 40mg and allopurinol 300mg , which exhibited comparable UL efficacy . | CONCLUSIONS |
University hospital . | METHODS |
The biologic activity of donor immune cells in allogeneic transplantation varied between graft sources . | CONCLUSIONS |
International collaborations have developed , including a planned meta-analysis to be undertaken with the UK Medical Research Council/National Cancer Institute of Canada Clinical Trials Group RADICALS ( Radiotherapy and Androgen Deprivation In Combination with Local Surgery ) trial and an innovative psycho-oncology sub-study to investigate a patient decision aid resource . | RESULTS |
This multiregional , double-blind study randomized 557 patients with T2DM ( mean glycated hemoglobin [ HbA1c ] , 6.9 % ) , previously treated with metformin and any sulfonylurea to receive either vildagliptin ( 50 mg twice daily ) or gliclazide plus metformin . | METHODS |
The clinical relevance of this study is that the difference in blood loss between the PCR and PS techniques does not need to be considered by surgeons when performing TKA . | CONCLUSIONS |
However , this strategy was also accompanied by increased carriage of azithromycin-resistant bacteria , the clinical consequences of which are uncertain , and will need careful monitoring and further study . | CONCLUSIONS |
Few randomized studies have investigated the impact of valved and non-valved power-injectable peripherally inserted central catheters ( PICCs ) in terms of incidence of occlusion , infection , malfunction and venous thrombosis . | OBJECTIVE |
This trial compared the efficacy/safety of two IV doses of AZD9773 , a polyclonal antibody to tumor necrosis factor - , in adult patients with severe sepsis/septic shock . | OBJECTIVE |
In the acupuncture group , Fengchi ( GB 20 ) , Wangu ( TE 5 ) , Tianzhu ( BL 10 ) , Neck-Jiaji ( EX-B 2 ) , etc. were selected , once daily , for 15 days . | METHODS |
We randomly allocated 75 women with recent gestational diabetes mellitus to either a Web-based lifestyle program ( Balance after Baby ) delivered over the first postpartum year or to a control group . | METHODS |
We found greater eccentric strength in the unexercised limbs of eccentric training participants between preintervention and midintervention and between preintervention and postintervention ( preintervention to midintervention : 30/s P = .05 ; preintervention to postintervention : 30/s P = .02 , 60/s P = .02 ) . | RESULTS |
The positive effects of weight loss on obesity-related risk factors diminish unless weight loss is maintained . | BACKGROUND |
Moreover , a significant difference was found between the intervention and the control group regarding the total quality of life ( F = 10.20 , p = 0.002 ) and health-functioning ( F = 8.64 , p = 0.004 ) , socioeconomic ( F = 12.45 , p = 0.001 ) , and family ( F = 8.52 , p = 0.005 ) subscales of quality of life . | RESULTS |
Evidence regarding the effectiveness of telemonitoring in managing the care of this chronic condition is mixed . | BACKGROUND |
All subjects attended the 18-month recall . | RESULTS |
Overweight and obesity during pregnancy represents a considerable health burden . | BACKGROUND |
The primary outcome was change in the number of annual chronic disease check-ups . | METHODS |
Quality of life ( QoL ) and cost-effectiveness will also be compared between therapies . | BACKGROUND |
Chronic hand and wrist pain is a common clinical issue for orthopaedic surgeons and rheumatologists . | OBJECTIVE |
There is increasing emphasis on the importance of intraocular pressure peaks and fluctuations as risk factors for glaucoma progression . | BACKGROUND |
Endotracheal intubation was not employed but only prepared as a standby for patients of the EA + GA group . | METHODS |
Enhanced computed tomography or magnetic resonance imaging of the liver was performed at one month after treatment and thereafter on a bi-monthly follow-up schedule . | METHODS |
Metabolic dysfunction is highly prevalent in older adults at risk of mobility disability , yet consistent associations were not observed between MetS and walking speed , lower extremity function , or self-reported disability after adjusting for known and potential confounders . | CONCLUSIONS |
Similarly , at 6 and 12 weeks , the score for fullness was also significantly higher in the whey group compared with both casein ( P = 0.038 and P = 0.022 , respectively ) and control ( P = 0.020 and P = 0.030 , respectively ) groups . | RESULTS |
The median time taken to complete the procedure was 5 minutes and 28 seconds for morcellation compared with 10 minutes and 12 seconds for electrosurgical resection ( P < .001 ) . | RESULTS |
The brief intervention investigated in this study does not appear to change beliefs regarding screening , self-perceived risk , or uptake of screening for HIV/HCV in this population . | CONCLUSIONS |
Faecal incontinence is an underreported health problem as the social isolation and stigma that patients experience makes it difficult for sufferers to discuss their condition with a physician . | OBJECTIVE |
Eating raisins significantly decreased glycated hemoglobin ( HbA1c ) level ( -0.12 % ; P = 0.004 ) , a significantly greater level decrease than seen with snack intake ( P = 0.036 ) . | RESULTS |
An analysis of time to first event of hospital admission was performed using Kaplan-Meier curves and Cox proportional hazard regression adjusting for possible confounders . | METHODS |
POCD occurred in 71 patients ( 22.3 % ) in the Dex-0 group , in 66 patients ( 20.6 % ) in the Dex-1 group , and 99 patients ( 31.4 % ) in the Dex-2 group . | RESULTS |
Fingolimod 05 mg caused more of the following adverse events versus placebo : lymphopenia ( 27 [ 8 % ] patients vs 0 patients ) , increased alanine aminotransferase ( 29 [ 8 % ] vs six [ 2 % ] ) , herpes zoster infection ( nine [ 3 % ] vs three [ 1 % ] ) , hypertension ( 32 [ 9 % ] vs 11 [ 3 % ] ) , first-dose bradycardia ( five [ 1 % ] vs one [ < 05 % ] ) , and first-degree atrioventricular block ( 17 [ 5 % ] vs seven [ 2 % ] ) . | RESULTS |
However , their role in reproduction is unclear . | BACKGROUND |
Of the intervention subjects , 85 % found that peer feedback was useful and 100 % found it effective . | RESULTS |
Studies comparing operative with nonoperative treatment of a stable burst fracture of the thoracolumbar junction in neurologically intact patients have not shown a meaningful difference at early follow-up . | BACKGROUND |
EA ( 3-4 Hz , 2.0-2 .2 mA ) was applied to bilateral Zhongfu ( LU 1 ) , Chize ( LU 5 ) and Ximen ( PC 4 ) beginning about 20 mm before the surgery in the EA + GA group . | METHODS |
All subjects had at least one mutation found in a gene known to cause albinism . | RESULTS |
Undergraduates ( N = 41 ) were randomly assigned to either an immediate treatment or waitlist control condition . | METHODS |
The degree of sputum eosinophil suppression by generic SFC was not inferior to original SFC , and this was not affected by treatments with the sequence of generic SFC first vs. original SFC second or original SFC first vs. generic SFC. In addition , there was no significant difference between treatments in terms of normalized gain in asthma control scores , including the number of patients found to have improved asthma control , irrespective of sequence , as change from baseline . | RESULTS |
Baseline NT-proBNP correlated with bulb and common carotid artery intima-media thickness , coronary calcium score , interleukin 6 , and cystatin C. | RESULTS |
Ten nave and 10 non-nave subjects completed study procedures . | RESULTS |
After controlling for confounders , extremely obese patients had a twofold to fourfold increase in postoperative complications , including the primary infectious outcome ( 18.8 % , adjusted OR 2.7 , CI 1.2-6 .1 ) , wound infection ( 18.8 % , adjusted OR 3.4 , CI 1.4-8 .0 ) , and emergency department visit ( 23.1 % , adjusted OR 2.2 , CI 1.03-4 .9 ) . | RESULTS |
The primary end point was the BSM area . | METHODS |
Patients will be randomized 2:1 ( rivaroxaban : VKA ) using 2 cardioversion strategies : the first approach is early cardioversion with the precardioversion anticoagulation goal of 1 to 5 days using rivaroxaban or usual therapy ( heparin + VKA ) . | METHODS |
Associations were still significant after adjustment for baseline B-type natriuretic peptide ( BNP ) concentration . | RESULTS |
In this prospective study , 90 healthy subjects were enrolled . | METHODS |
RESULTS . | METHODS |
Optimal LDX dose ( 30 , 50 , or 70 mg/day ) was determined for parents during a 3-week open-label titration , followed by a within-subjects trial of the acute impact of LDX and placebo on observable parent-child interactions . | METHODS |
Two of the most commonly used recreational drugs in the western world , 3,4-methylenedioxymethamphetamine ( MDMA or `` ecstasy '' ) and ethanol ( alcohol ) , are also often used in combination . | BACKGROUND |
Thus , risk factors for developing SUD should be addressed early in life by adequate preventive measures reaching out to children , adolescents , and their families . | BACKGROUND |
Controls were age matched healthy individuals with no symptoms of AMD . | METHODS |
Questions assessed physicians ' attitudes and experiences regarding : 1 ) self-regulation , 2 ) feedback on knowledge and clinical care , 3 ) demonstrating knowledge and clinical competence , 4 ) frequency of use and effectiveness of methods to assess or improve clinical care , and 5 ) transparency . | METHODS |
Both GMRs were within the predefined bioequivalence interval ( 90 % C.Is , 0.80-1 .25 ) . | RESULTS |
This first study of COX-2 inhibition in provoked asthma found no negative effects of etoricoxib on allergen-induced airflow obstruction and sputum eosinophils , basal lung function , or methacholine responsiveness . | CONCLUSIONS |
Zelen-design clinical trial ( randomization occurred before informed consent ) , in Victoria , Australia ( February 2010-December 2012 ) . | METHODS |
A dose response for intensity of use was observed at 30 days ( p = 0.001 ) and 90 days ( p = 0.003 ) . | RESULTS |
In addition , cross-lagged analysis indicated that both positive and negative affect may influence creativity in IBMT group ( not RT group ) . | RESULTS |
Clinical success rates were 100 % in both arms . | RESULTS |
This study is registered with ClinicalTrials.gov , number NCT01129518 . | METHODS |
Culturally tailored education programs that increase liver cancer awareness can be effective in increasing HBV screening among underserved Asian American populations . | CONCLUSIONS |
Amrubicin , a third-generation anthracycline and potent topoisomerase II inhibitor , showed promising activity in small-cell lung cancer ( SCLC ) in phase II trials . | OBJECTIVE |
Linear mixed models showed that those receiving a meditation-based intervention ( MBSR or MBTI ) had significantly greater reductions on TWT minutes ( 43.75 vs 1.09 ) , PSAS ( 7.13 vs 0.16 ) , and ISI ( 4.56 vs 0.06 ) from baseline-to-post compared to SM . | RESULTS |
At 12 weeks , the progression-free rate was 26 % ( seven out of 27 patients ) for nintedanib , and 0 % for afatinib and Combi40 groups . | RESULTS |
Until recently , non-specific low back pain ( NSLBP ) in adolescents was considered a rare phenomenon unlike in adults . | BACKGROUND |
HCV G4 viral variants with a T54A/T mutation were detected in two of these patients , as well as two other patients with detectable HCV RNA at the end of telaprevir treatment . | RESULTS |
In contrast to earlier studies , the improvement in cardiorespiratory fitness in a cohort of overweight/obese participants undertaking aerobic interval training in a real world setting was modest . | CONCLUSIONS |
Postoperatively , mean IPSS was 11.1 4.1 in TURP group and 11.7 3.6 in laser group ( P = .64 ) . | RESULTS |
Into the arm 1 , the 96.4 % has tested positive for QPT . | RESULTS |
To evaluate the efficacy and safety of omega-3 fatty acid supplementation in children with nonalcoholic fatty liver disease ( NAFLD ) . | OBJECTIVE |
An open-label cohort multicenter randomized study was conducted . | METHODS |
In the SNB group , patients received ultrasound-guided SNB with 20 ml 0.375 % ropivacaine and periarticular infiltration with 20 ml normal saline and 0.3 mg epinephrine . | METHODS |
Secondary analyses were completed for children who met Rome III criteria for irritable bowel syndrome . | RESULTS |
This trial was registered at clinicaltrials.gov as NCT01245010 . | CONCLUSIONS |
After healing of the underlying condition , the stent was removed in six patients ( 50.0 % ) . | RESULTS |
Rikkunshito ( RKT ) , a traditional Japanese medicine , acts as a prokinetic agent and improves gastric emptying and gastric accommodation . | BACKGROUND |
After CR , the therapy group had a significant reduction in DIS and NEG symptom dimensions compared to the TAU group . | RESULTS |
According to BMI categorisation , 41.4 % of participants were underweight or normal weight , 34.3 % were overweight and 24.3 % were obese . | RESULTS |
Digital color photographs and fluorescein angiograms at baseline and 1 and 2 years were evaluated for GA , and the total area of GA was measured by 2 graders masked to treatment ; differences were adjudicated . | METHODS |
These findings suggest that our cost/resource effective , brief group psychoeducational program , when administered early and by the same team who confirmed and communicated the diagnosis of PNES , may contribute to significant functional improvement among participating patients . | CONCLUSIONS |
Healthy subjects ( mean age 25.9 yrs ) and patients with COPD ( mean age 66 yrs , mean post-bronchodilator FEV1 60.1 % predicted normal value ) were randomised 2:1 to active treatment ( 400 , 1000 or 2800 g delivered doses of AZD9164 ) or placebo . | METHODS |
34 exercise-conditioned adult Husky-Pointer dogs . | METHODS |
However , study on antihypertensive treatment for surgical patients with spontaneous intracerebral hemorrhage is insufficient . | BACKGROUND |
GA-only patients received a standardized general anesthetic . | METHODS |
Prophylactic IVC filters were placed in two patients . | METHODS |
Evidence-based treatments for posttraumatic stress disorder ( PTSD ) have not been established for adolescents despite high prevalence of PTSD in this population . | OBJECTIVE |
To evaluate the proportion of patients achieving clinically meaningful improvement of lower urinary tract symptoms suggestive of benign prostatic hyperplasia ( BPH-LUTS ) with tadalafil using two definitions of response . | OBJECTIVE |
Passive resistive torque and maximum voluntary contraction were measured with a dynamometer . | METHODS |