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stringlengths 18
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class label 22
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They are characterized by a severe paroxysmal EEG disturbance that may permanently alter the critical synaptogenesis by strengthening synaptic contacts that should have been naturally " pruned . " The much more common benign epilepsy with centrotemporal spikes is also related to LKS and CSWS by a common pathophysiology . | {
"id": "C0014544",
"pos": [
225,
233
],
"name": "epilepsy"
} | {
"id": "C0282512",
"pos": [
280,
283
],
"name": "LKS"
} | 5cause_of
|
When an S2'-P2 ' interaction is involved ( factor IX , antithrombin , APPI ) , beta-branching and increased side chain length are detrimental . | {
"id": "C0003438",
"pos": [
55,
67
],
"name": "antithrombin"
} | {
"id": "C0037420",
"pos": [
17,
28
],
"name": "interaction"
} | 0NA
|
Histopathological analyses were performed in ligamentum flavum ( LF ) hypertrophy patients with lumbar spinal stenosis ( LSS ) and lumbar disc herniation ( LDH ) . | {
"id": "C0020564",
"pos": [
70,
81
],
"name": "hypertrophy"
} | {
"id": "C0206327",
"pos": [
45,
62
],
"name": "ligamentum flavum"
} | 0NA
|
This paradigm may help explain why microvascular dysfunction is such a powerful predictor of cardiovascular events and help identify new approaches to treatment and prevention . | {
"id": "C0199176",
"pos": [
165,
175
],
"name": "prevention"
} | {
"id": "C0007226",
"pos": [
93,
107
],
"name": "cardiovascular"
} | 0NA
|
There is significant evidence that patients with diabetes have increased risk of developing certain cancers , especially colorectal , pancreatic and primary hepatic cancer . | {
"id": "C0030274",
"pos": [
134,
144
],
"name": "pancreatic"
} | {
"id": "C0006826",
"pos": [
100,
107
],
"name": "cancers"
} | 0NA
|
Furthermore , being nationally recognised qualifications we hope the courses will have a positive effect not only on personnel retainment but on recruitment . | {
"id": "C1446409",
"pos": [
89,
97
],
"name": "positive"
} | {
"id": "C0271510",
"pos": [
145,
156
],
"name": "recruitment"
} | 0NA
|
Nicotine , in doses comparable to the amounts absorbed from smoke , also increased breathing and tracheal smooth muscle tension when injected into the vertebral circulation of recipient dogs . | {
"id": "C0040578",
"pos": [
97,
105
],
"name": "tracheal"
} | {
"id": "C0549207",
"pos": [
151,
160
],
"name": "vertebral"
} | 0NA
|
STEAP1 gene is overexpressed in several kinds of tumors , particularly in prostate cancer . | {
"id": "C0027651",
"pos": [
49,
55
],
"name": "tumors"
} | {
"id": "C0376358",
"pos": [
74,
89
],
"name": "prostate cancer"
} | 0NA
|
Plasma concentrations of valsartan and hydrochlorothiazide were determined simultaneously by LC-MS/MS . | {
"id": "C0020261",
"pos": [
39,
58
],
"name": "hydrochlorothiazide"
} | {
"id": "C0216784",
"pos": [
25,
34
],
"name": "valsartan"
} | 0NA
|
In contrast , fecal extracts from mice exposed to γ-HBCD contained multiple isomers of monohydroxy-pentabromocyclododecene , dihydroxy-pentabromocyclododecene , and dihydroxy-pentabromocyclododecadiene , while in liver and adipose tissues extracts only a single monohydroxy-pentabromocyclododecane metabolite was observed . | {
"id": "C0023884",
"pos": [
213,
218
],
"name": "liver"
} | {
"id": "C0001527",
"pos": [
223,
238
],
"name": "adipose tissues"
} | 0NA
|
Difficulty swallowing due to damage of the vagus nerve is one of the most devastating complications of surgery in and around the medulla oblongata ; therefore , intraoperative anatomical and functional evaluation of this nerve is crucial . | {
"id": "C0027740",
"pos": [
221,
226
],
"name": "nerve"
} | {
"id": "C0042276",
"pos": [
43,
54
],
"name": "vagus nerve"
} | 0NA
|
Two hundred ten patients ( 5.6 % ) had irreversible renal parenchymal disease and significantly higher mortality than men and women with other causes of hypertension . | {
"id": "C0020538",
"pos": [
153,
165
],
"name": "hypertension"
} | {
"id": "C1841992",
"pos": [
52,
77
],
"name": "renal parenchymal disease"
} | 0NA
|
In particular , patients with a rapid transition from CIS to multiple sclerosis had an elevated CD4/CD14 ratio . | {
"id": "C0007099",
"pos": [
54,
57
],
"name": "CIS"
} | {
"id": "C0026769",
"pos": [
61,
79
],
"name": "multiple sclerosis"
} | 0NA
|
As a result of breath holding that results from the stimulation of cold receptors there is a greater opportunity for exposure and transfer of the contents of the lungs to the pulmonary circulation . | {
"id": "C0024109",
"pos": [
162,
167
],
"name": "lungs"
} | {
"id": "C0235744",
"pos": [
15,
29
],
"name": "breath holding"
} | 0NA
|
The relative CSAs of trunk muscles to their body weight in the LDD group were significantly smaller than those in the non-LDD group ( rectus abdominis : p = 0.011 ; obliques : p = 0.024 ; quadratus lumborum : p = 0.006 ; lumbar erector spinae plus multifidus : p = 0.001 ) . | {
"id": "C0026845",
"pos": [
27,
34
],
"name": "muscles"
} | {
"id": "C0224319",
"pos": [
260,
270
],
"name": "multifidus"
} | 0NA
|
A 13-year-old male child treated medically as tuberculosis of spine elsewhere for 1 year , came with complete paraplegia , dorsolumbar kyphosis and intermittently discharging sinus in the back . | {
"id": "C0037949",
"pos": [
62,
67
],
"name": "spine"
} | {
"id": "C0016169",
"pos": [
177,
182
],
"name": "sinus"
} | 0NA
|
To our knowledge , this is the first report of an Italian case of lethal krokodil abuse , that occurred in a 39-year-old man , who died suddenly after transportation to the Emergency Department ( ED ) for hyperthermia associated with sweating , dyspnoea and tachycardia . | {
"id": "C0015967",
"pos": [
205,
217
],
"name": "hyperthermia"
} | {
"id": "C0038990",
"pos": [
234,
242
],
"name": "sweating"
} | 0NA
|
As the molecular processes that control mRNA translation and ribosome biogenesis in the eukaryotic cell are extremely complex and multilayered , their deregulation can in principle occur at multiple levels , leading to both disease and cancer pathogenesis . | {
"id": "C0006826",
"pos": [
236,
242
],
"name": "cancer"
} | {
"id": "C0012634",
"pos": [
224,
231
],
"name": "disease"
} | 0NA
|
We report the resection of a CA located underneath the dominant WA discussing the functional and anatomical evidence provided by fMRI , dissections with Klingler 's technique , and intraoperative mapping during awake surgery . | {
"id": "C0015252",
"pos": [
14,
23
],
"name": "resection"
} | {
"id": "C0012737",
"pos": [
136,
147
],
"name": "dissections"
} | 0NA
|
All receptors identified so far bind somatostatin-14 and somatostatin-28 with high affinity . | {
"id": "C0074854",
"pos": [
57,
72
],
"name": "somatostatin-28"
} | {
"id": "C0037659",
"pos": [
37,
52
],
"name": "somatostatin-14"
} | 16is_modification_of
|
If left untreated , combined with deformities directly related to the fracture , it may lead to disability . | {
"id": "C0016658",
"pos": [
70,
78
],
"name": "fracture"
} | {
"id": "C0000768",
"pos": [
34,
45
],
"name": "deformities"
} | 0NA
|
Of the latter group , 66 ( 64 % ) were for lesions less than 2 cm in diameter and were situated in areas other than the face . | {
"id": "C0221198",
"pos": [
43,
50
],
"name": "lesions"
} | {
"id": "C0015450",
"pos": [
120,
124
],
"name": "face"
} | 0NA
|
The analysis of the downstream effects predicted decreases in emotional and aggressive behavior , which corroborates the results from preclinical and clinical studies of the use of Rhodiola for the treatment of depression and anxiety . | {
"id": "C0003467",
"pos": [
226,
233
],
"name": "anxiety"
} | {
"id": "C0013987",
"pos": [
62,
71
],
"name": "emotional"
} | 15interprets
|
Muscles from vitamin E-deficient mice and rats were more prone than normal to damage during contractile activity ; the tissue rather than the plasma level of the vitamin is probably the more important factor in this respect . | {
"id": "C0010957",
"pos": [
78,
84
],
"name": "damage"
} | {
"id": "C0026845",
"pos": [
0,
7
],
"name": "Muscles"
} | 0NA
|
The present results indicate that wine phenolics decrease Hsp levels in tumor cells and tumor and endothelial cell populations . | {
"id": "C0027651",
"pos": [
88,
93
],
"name": "tumor"
} | {
"id": "C0359916",
"pos": [
39,
48
],
"name": "phenolics"
} | 0NA
|
The eye is the most susceptible body part to laser light injury . | {
"id": "C0015392",
"pos": [
4,
7
],
"name": "eye"
} | {
"id": "C0229962",
"pos": [
32,
41
],
"name": "body part"
} | 0NA
|
Additionally , pain-evoked ERPs are attenuated by hypertension and baroreceptor activity , through as yet unclear mechanisms . | {
"id": "C0020538",
"pos": [
50,
62
],
"name": "hypertension"
} | {
"id": "C0015214",
"pos": [
27,
31
],
"name": "ERPs"
} | 0NA
|
The diagnosis was established in all patients by the surgical removal of adult worms from the lesions . | {
"id": "C0221198",
"pos": [
94,
101
],
"name": "lesions"
} | {
"id": "C0015252",
"pos": [
53,
69
],
"name": "surgical removal"
} | 0NA
|
Patient and practitioner values are the shortest leg of the stool . | {
"id": "C0023216",
"pos": [
49,
52
],
"name": "leg"
} | {
"id": "C0015733",
"pos": [
60,
65
],
"name": "stool"
} | 0NA
|
To improve the inherent defects of chemotherapy and photothermal therapy ( PTT ) , we design a novel thermochromism-induced temperature self-regulation and alternating photothermal system based on iodine ( I | {
"id": "C0013216",
"pos": [
35,
47
],
"name": "chemotherapy"
} | {
"id": "C0005903",
"pos": [
124,
135
],
"name": "temperature"
} | 0NA
|
In all these women previously performed dilatation and curettage was unsuccessful . | {
"id": "C0002940",
"pos": [
40,
50
],
"name": "dilatation"
} | {
"id": "C0010468",
"pos": [
55,
64
],
"name": "curettage"
} | 0NA
|
The most common medications involved were phenytoin and albuterol . | {
"id": "C0013227",
"pos": [
16,
27
],
"name": "medications"
} | {
"id": "C0031507",
"pos": [
42,
51
],
"name": "phenytoin"
} | 0NA
|
The PAA provides a faster , dryer , more complete , and more surgically satisfying resection than the ACA . | {
"id": "C0015252",
"pos": [
83,
92
],
"name": "resection"
} | {
"id": "C0267964",
"pos": [
4,
7
],
"name": "PAA"
} | 0NA
|
Thirty-two partially stabilized zirconia implants were placed into the mandibles of 8 monkeys . | {
"id": "C0021102",
"pos": [
41,
49
],
"name": "implants"
} | {
"id": "C0024687",
"pos": [
71,
80
],
"name": "mandibles"
} | 0NA
|
Tracheal intubation was difficult in six patients of the atracurium group , all of whom had diabetes mellitus and varying degrees of neck stiffness . | {
"id": "C0011849",
"pos": [
92,
109
],
"name": "diabetes mellitus"
} | {
"id": "C0040578",
"pos": [
0,
8
],
"name": "Tracheal"
} | 0NA
|
This promotes efficient RPA2S4-S8 and CHK1S345 phosphorylation and thereby prevents cellular senescence , IPF and carcinoma formation . | {
"id": "C0007097",
"pos": [
114,
123
],
"name": "carcinoma"
} | {
"id": "C0034069",
"pos": [
106,
109
],
"name": "IPF"
} | 0NA
|
The number of attempts made , time to intubation , and medications used are presented . | {
"id": "C0013227",
"pos": [
55,
66
],
"name": "medications"
} | {
"id": "C0021925",
"pos": [
38,
48
],
"name": "intubation"
} | 0NA
|
Although this may seem to be a simple and basic concept , it assumes tremendous importance in liver transplantation in which the differential diagnosis between biliary and arterial complications or graft rejection and malfunctioning is often a difficult one . | {
"id": "C0023911",
"pos": [
94,
115
],
"name": "liver transplantation"
} | {
"id": "C0003842",
"pos": [
172,
180
],
"name": "arterial"
} | 0NA
|
This report describes an illustrative case of a 39-year-old woman who presented to the ED with a two-year history of right leg spasms and low back pain that had become so severe in the preceding two days that she was unable to ambulate . | {
"id": "C0205082",
"pos": [
171,
177
],
"name": "severe"
} | {
"id": "C0024031",
"pos": [
138,
151
],
"name": "low back pain"
} | 0NA
|
In RCCs and breast cancers , PKM2 overexpression was correlated with elevated S202/203 phosphorylation , activated mTORC1 and inhibited autophagy . | {
"id": "C0007134",
"pos": [
3,
7
],
"name": "RCCs"
} | {
"id": "C0006142",
"pos": [
12,
26
],
"name": "breast cancers"
} | 0NA
|
12 , 547 - 554 ) procedure for the hydrolysis of complex carbohydrates such as gangliosides employs 0.1 n H+ at 80 degrees C for 60 min . | {
"id": "C0184661",
"pos": [
17,
26
],
"name": "procedure"
} | {
"id": "C0007004",
"pos": [
57,
70
],
"name": "carbohydrates"
} | 0NA
|
In the remaining 65 % of the patients , a further reduction in type and screen investigations of 15 % could be achieved using the preoperative haemoglobin concentration . | {
"id": "C0019046",
"pos": [
143,
154
],
"name": "haemoglobin"
} | {
"id": "C1261322",
"pos": [
79,
93
],
"name": "investigations"
} | 0NA
|
Since the α1-adrenergic antagonist prazosin ( PRZ ) was introduced into medicine as a treatment for hypertension and benign prostate hyperplasia , several studies have shown that PRZ induces apoptosis in various cell types and interferes with endocytotic trafficking . | {
"id": "C0013227",
"pos": [
72,
80
],
"name": "medicine"
} | {
"id": "C1704272",
"pos": [
124,
144
],
"name": "prostate hyperplasia"
} | 0NA
|
We have examined the relationships between architectural changes of trabecular bone and vertebral crush fractures in 44 male patients with osteoporosis ( bone mineral density more than 2.5 SD below the young adult value ) . | {
"id": "C0029456",
"pos": [
139,
151
],
"name": "osteoporosis"
} | {
"id": "C0222660",
"pos": [
68,
83
],
"name": "trabecular bone"
} | 0NA
|
This article describes the Active Vertical Corrector ( AVC ) , which is a simple removable or fixed orthodontic appliance that intrudes the posterior teeth in both the maxilla and mandible by reciprocal forces . | {
"id": "C0441421",
"pos": [
94,
121
],
"name": "fixed orthodontic appliance"
} | {
"id": "C0024947",
"pos": [
168,
175
],
"name": "maxilla"
} | 0NA
|
Patients with temporal lobe epilepsy who experience seizures weekly or more frequently , experience a lack of aura , use levetiracetam , or take antidepressants are all at a higher risk of suicide and should be monitored closely . | {
"id": "C0038661",
"pos": [
189,
196
],
"name": "suicide"
} | {
"id": "C0377265",
"pos": [
121,
134
],
"name": "levetiracetam"
} | 0NA
|
The improved therapeutic index of DTS-201 compared with free doxorubicin was confirmed in three tumor xenograft models of prostate , breast , and lung cancer . | {
"id": "C0006141",
"pos": [
133,
139
],
"name": "breast"
} | {
"id": "C0033572",
"pos": [
122,
130
],
"name": "prostate"
} | 0NA
|
Adrenocortical carcinoma is a rare tumor that arises from the adrenal cortex , with an estimated incidence of 0.5 % to 2 % per 1 million patients yearly . | {
"id": "C0001613",
"pos": [
62,
76
],
"name": "adrenal cortex"
} | {
"id": "C0206686",
"pos": [
0,
24
],
"name": "Adrenocortical carcinoma"
} | 11finding_site_of
|
In long-term follow-up , 1 patient required esophageal dilatation of the anastomosis . | {
"id": "C0332853",
"pos": [
73,
84
],
"name": "anastomosis"
} | {
"id": "C0192389",
"pos": [
44,
65
],
"name": "esophageal dilatation"
} | 0NA
|
Immunoblot is a useful technique to demonstrate the local synthesis of antibodies in ocular toxoplasmosis by comparison of recognition patterns between serum and ocular fluids . | {
"id": "C0020985",
"pos": [
0,
10
],
"name": "Immunoblot"
} | {
"id": "C0040561",
"pos": [
85,
105
],
"name": "ocular toxoplasmosis"
} | 0NA
|
Contrary to the gross lesion picture known there were no changes in the rumen , reticulum , and omasum which were not sufficiently developed during that period . | {
"id": "C0221198",
"pos": [
16,
28
],
"name": "gross lesion"
} | {
"id": "C0025344",
"pos": [
153,
159
],
"name": "period"
} | 0NA
|
The resection in VATS of giant bullous emphysema by stapling device associated to reinforcement in PTFE reduces duration of air leaks and hospitalisation and improves pulmonary function . | {
"id": "C0015252",
"pos": [
4,
13
],
"name": "resection"
} | {
"id": "C0231921",
"pos": [
167,
185
],
"name": "pulmonary function"
} | 0NA
|
In the caudate nucleus of KO rats , the volume fraction of the ECS and the diffusion coefficient were increased , with significantly decreased tortuosity ; no significant changes in brain ISF flow were demonstrated . | {
"id": "C0006104",
"pos": [
182,
187
],
"name": "brain"
} | {
"id": "C0013806",
"pos": [
63,
66
],
"name": "ECS"
} | 9direct_procedure_site_of
|
In this review , we address some anatomical and physiological features that distinguish pulmonary artery , capillary , and vein endothelium . | {
"id": "C0034052",
"pos": [
88,
104
],
"name": "pulmonary artery"
} | {
"id": "C0006901",
"pos": [
107,
116
],
"name": "capillary"
} | 0NA
|
As part of an ongoing longitudinal twin study , data from both MRI brain scanning and from neuropsychological testing were obtained from 139 male-male twin pairs ( 72 monozygotic [ MZ ] and 67 dizygotic [ DZ ] ) , 69 - 80 years old at the time of examination . | {
"id": "C0024485",
"pos": [
63,
66
],
"name": "MRI"
} | {
"id": "C0031809",
"pos": [
247,
258
],
"name": "examination"
} | 0NA
|
Non-responsiveness to aspirin as detected by laboratory tests may identify patients at high risk for future vascular events . | {
"id": "C0004057",
"pos": [
22,
29
],
"name": "aspirin"
} | {
"id": "C0022885",
"pos": [
45,
61
],
"name": "laboratory tests"
} | 0NA
|
A 51-year-old man presented with unilateral corneal endotheliitis with linear keratic precipitates and coin-shaped lesions . | {
"id": "C0221198",
"pos": [
115,
122
],
"name": "lesions"
} | {
"id": "C0423262",
"pos": [
44,
65
],
"name": "corneal endotheliitis"
} | 0NA
|
Here we present the case of an elderly 89-year-old Caucasian male who was diagnosed with SCC of the prostate . | {
"id": "C0033572",
"pos": [
100,
108
],
"name": "prostate"
} | {
"id": "C0086582",
"pos": [
61,
65
],
"name": "male"
} | 0NA
|
The incidence of anastomotic leaks , including leaks after stoma reversal , was not statistically different between PA and HP ( RR = 1.42 , 95 % CI 0.41 - 4.87 , p = 0.58 ) while risk of a postoperative intra-abdominal abscess was lower after PA than after HP ( RR = 0.34 , 95 % CI 0.12 - 0.96 , p = 0.04 ) . | {
"id": "C1955856",
"pos": [
59,
64
],
"name": "stoma"
} | {
"id": "C0243001",
"pos": [
211,
234
],
"name": "intra-abdominal abscess"
} | 0NA
|
Adhesion-promoting activity in whole PCM was sensitive to treatments with trypsin , acid , and heat but stable to dithiothreitol treatment . | {
"id": "C0033677",
"pos": [
37,
40
],
"name": "PCM"
} | {
"id": "C0020517",
"pos": [
45,
54
],
"name": "sensitive"
} | 0NA
|
Excision of involved portal vein during pancreatoduodenectomy for carcinoma of the head of the pancreas is a feasible and valid procedure in the absence of metastases . | {
"id": "C0030274",
"pos": [
95,
103
],
"name": "pancreas"
} | {
"id": "C0085162",
"pos": [
40,
61
],
"name": "pancreatoduodenectomy"
} | 9direct_procedure_site_of
|
Blood samples were collected and serum glucose , lipid profiles , total protein , albumin , total calcium , magnesium , vitamin B12 , and vitamin D levels were analyzed . | {
"id": "C0001924",
"pos": [
82,
89
],
"name": "albumin"
} | {
"id": "C0014695",
"pos": [
138,
147
],
"name": "vitamin D"
} | 0NA
|
In this study , we report the results from the largest cohort to date of newly diagnosed adult immune thrombocytopenia patients randomized to treatment with dexamethasone alone or in combination with rituximab . | {
"id": "C0011777",
"pos": [
157,
170
],
"name": "dexamethasone"
} | {
"id": "C0242584",
"pos": [
95,
118
],
"name": "immune thrombocytopenia"
} | 0NA
|
This type of procedure is justified by failure of other procedures aiming to stabilise the hips in spastic patients . | {
"id": "C0019552",
"pos": [
91,
95
],
"name": "hips"
} | {
"id": "C0184661",
"pos": [
13,
22
],
"name": "procedure"
} | 0NA
|
From this time wines under cork and screwcap lost SO2 at a similar rate and retained dissolved CO2 equally well , indicating that both types of closure presented a similar effective barrier to gas movement . | {
"id": "C0185003",
"pos": [
144,
151
],
"name": "closure"
} | {
"id": "C0007012",
"pos": [
95,
98
],
"name": "CO2"
} | 0NA
|
On the last day , their blood as well as their liver and kidney were used for biochemical and histopathological analyses , respectively . | {
"id": "C0022646",
"pos": [
57,
63
],
"name": "kidney"
} | {
"id": "C0023884",
"pos": [
47,
52
],
"name": "liver"
} | 0NA
|
So far , microRNAs have been considered as important intracellular mediators in maintaining proper cardiac function and hemostasis , and have been proposed as potential therapeutic targets in cardiovascular disease . | {
"id": "C0007222",
"pos": [
192,
214
],
"name": "cardiovascular disease"
} | {
"id": "C0019116",
"pos": [
120,
130
],
"name": "hemostasis"
} | 0NA
|
Specifically , the avoidance of negative emotions was associated with higher levels of anxiety for those with lower attentional control . | {
"id": "C0003467",
"pos": [
87,
94
],
"name": "anxiety"
} | {
"id": "C0013987",
"pos": [
41,
49
],
"name": "emotions"
} | 15interprets
|
CTC is a feasible and minimally invasive method for full exploration of the colon after surgical resection allowing detection of cancer recurrence , metachronous disease , and distant metastases in one single study , and represents a valid alternative to conventional colonoscopy in this patient population . | {
"id": "C0009368",
"pos": [
76,
81
],
"name": "colon"
} | {
"id": "C0009378",
"pos": [
268,
279
],
"name": "colonoscopy"
} | 9direct_procedure_site_of
|
The use of morphine , at a volume of 0.25 mL kg 0.1 , administered epidurally over the thoracic vertebrae provided longer lasting analgesia than when deposited over the lumbar vertebrae . | {
"id": "C0039987",
"pos": [
87,
105
],
"name": "thoracic vertebrae"
} | {
"id": "C0024091",
"pos": [
169,
185
],
"name": "lumbar vertebrae"
} | 0NA
|
180 individuals with MCI were identified and randomly divided into intervention ( folic acid 400 µg/day , n = 90 ) and convention ( n = 90 ) groups . | {
"id": "C0016410",
"pos": [
82,
92
],
"name": "folic acid"
} | {
"id": "C0184661",
"pos": [
67,
79
],
"name": "intervention"
} | 0NA
|
Traditional intermittent courses of melphalan and prednisone still holds its role as standard induction therapy . | {
"id": "C0025241",
"pos": [
36,
45
],
"name": "melphalan"
} | {
"id": "C0032952",
"pos": [
50,
60
],
"name": "prednisone"
} | 0NA
|
Thus the co-administering of Asp with another drug that can suppress its side effect while having no impact on its anti-inflammatory activity would be ideal . | {
"id": "C0013227",
"pos": [
46,
50
],
"name": "drug"
} | {
"id": "C0004015",
"pos": [
29,
32
],
"name": "Asp"
} | 0NA
|
The PCOS model was induced by daily administration of DHEA s.c . | {
"id": "C0011185",
"pos": [
54,
58
],
"name": "DHEA"
} | {
"id": "C0032460",
"pos": [
4,
8
],
"name": "PCOS"
} | 0NA
|
In opposition RAAS blockade may reverse Klotho loss during CKD in both experimental and human studies , with direct and indirect expected beneficial effects on the kidney and cardiovascular system . | {
"id": "C0022646",
"pos": [
164,
170
],
"name": "kidney"
} | {
"id": "C1561643",
"pos": [
59,
62
],
"name": "CKD"
} | 11finding_site_of
|
Knowledge of normal tibial torsion is mandatory during total knee replacement ( TKR ) , deformity correction and fracture management of tibia . | {
"id": "C0040184",
"pos": [
136,
141
],
"name": "tibia"
} | {
"id": "C0426900",
"pos": [
20,
34
],
"name": "tibial torsion"
} | 11finding_site_of
|
The optic nerve is organized virtually in the same fashion as the optic nerve head . | {
"id": "C0029130",
"pos": [
4,
15
],
"name": "optic nerve"
} | {
"id": "C0029127",
"pos": [
66,
82
],
"name": "optic nerve head"
} | 0NA
|
gammadelta T cells were specifically recruited into the CNS in response to this parasitic infection , and they were able to target the infected brain within 12 h after transfer . | {
"id": "C0006104",
"pos": [
144,
149
],
"name": "brain"
} | {
"id": "C0030499",
"pos": [
80,
99
],
"name": "parasitic infection"
} | 0NA
|
There is no strong evidence for any particular antimicrobial agent for the prevention of amputation , resolution of infection , or ulcer healing . | {
"id": "C0009450",
"pos": [
116,
125
],
"name": "infection"
} | {
"id": "C0002688",
"pos": [
89,
99
],
"name": "amputation"
} | 0NA
|
These kinetic parameters as well as the uptake by intact cells at 0 degrees C or by frozen and thawed cells , are consistent with operation of a saturable carrier . | {
"id": "C0007294",
"pos": [
155,
162
],
"name": "carrier"
} | {
"id": "C0543467",
"pos": [
130,
139
],
"name": "operation"
} | 0NA
|
Abscesses that contained bacteria were scattered throughout the liver . | {
"id": "C0023884",
"pos": [
64,
69
],
"name": "liver"
} | {
"id": "C0000833",
"pos": [
0,
9
],
"name": "Abscesses"
} | 0NA
|
Three morphological units of the nucleus were distinguished ( parts : oral , principal and caudal ) and four subunits ( zones : hypothalamic , optic , basal and central ) as a starting point to work out a model of its cytomorphological heterogeneity . | {
"id": "C0226896",
"pos": [
70,
74
],
"name": "oral"
} | {
"id": "C0020663",
"pos": [
128,
140
],
"name": "hypothalamic"
} | 0NA
|
The aim of the study was to test the predictive power of the JDCS model in relation with one year incidence of sick leave in a large cohort of workers . | {
"id": "C0221423",
"pos": [
111,
115
],
"name": "sick"
} | {
"id": "C0022885",
"pos": [
28,
32
],
"name": "test"
} | 0NA
|
With a shape-dependent surface acidity , hydrothermal stability , and high photoactivity , these Nb(2)O(5 ) nanorods are a unique and exciting nanomaterial for non-classical photocatalytic mineralization of organic compounds in water . | {
"id": "C0029224",
"pos": [
207,
224
],
"name": "organic compounds"
} | {
"id": "C0043047",
"pos": [
228,
233
],
"name": "water"
} | 0NA
|
The purpose of this study was to compare the effects of bare metal stents ( BMS ) and drug-eluting stents ( DES ) implantation on circulating endothelial cells ( CECs ) which have been proposed as cellular markers of endothelial dysfunction following percutaneous coronary intervention ( PCI ) . | {
"id": "C1532338",
"pos": [
251,
285
],
"name": "percutaneous coronary intervention"
} | {
"id": "C0021107",
"pos": [
114,
126
],
"name": "implantation"
} | 0NA
|
Existing pericardial substitutes , used for the prevention of pericardial and pleural adhesions to the epicardium , are in the form of a patch . | {
"id": "C0031050",
"pos": [
62,
73
],
"name": "pericardial"
} | {
"id": "C0264542",
"pos": [
78,
95
],
"name": "pleural adhesions"
} | 0NA
|
Diminished oxygen delivery and edema may additionally have contributed to peripheral nerve ischemia . | {
"id": "C0013604",
"pos": [
31,
36
],
"name": "edema"
} | {
"id": "C0429622",
"pos": [
11,
26
],
"name": "oxygen delivery"
} | 0NA
|
The dose-related positive inotropic effect of levamisole 5 - 200 micrograms/ml was not antagonised by practolol but was absent in atria from reserpinized animals . | {
"id": "C1446409",
"pos": [
17,
25
],
"name": "positive"
} | {
"id": "C0023556",
"pos": [
46,
56
],
"name": "levamisole"
} | 0NA
|
We analyze the regulation function of GPCRs in the metabolic network of AD based on the drug screen results , which may be helpful for the study of the off-target effect and the side effect of drugs . | {
"id": "C0013227",
"pos": [
193,
198
],
"name": "drugs"
} | {
"id": "C0038577",
"pos": [
88,
99
],
"name": "drug screen"
} | 6component_of
|
Upper gastrointestinal series revealed mesenterioaxial volvulus of the stomach in which the pylorus was displaced to the left . | {
"id": "C0034196",
"pos": [
92,
99
],
"name": "pylorus"
} | {
"id": "C0203057",
"pos": [
0,
29
],
"name": "Upper gastrointestinal series"
} | 0NA
|
Destruction of the blood supply to tendons adversely affects healing of repaired flexor tendons . | {
"id": "C0039508",
"pos": [
35,
42
],
"name": "tendons"
} | {
"id": "C0043240",
"pos": [
61,
68
],
"name": "healing"
} | 0NA
|
Acute RGES can result in a series of symptoms associated with dyspepsia , which is beneficial to the treatment of obesity . | {
"id": "C0028754",
"pos": [
114,
121
],
"name": "obesity"
} | {
"id": "C0013395",
"pos": [
62,
71
],
"name": "dyspepsia"
} | 0NA
|
In total 75 pairs of Class II restorations , 68 premolars and 82 molars , all in occlusion , were placed by two dentists . | {
"id": "C0001168",
"pos": [
81,
90
],
"name": "occlusion"
} | {
"id": "C0026367",
"pos": [
65,
71
],
"name": "molars"
} | 0NA
|
Hospital stay was long with thransthoracic resection ( WMD = -5.80 , 95 % CI -10.38- -1.23 ) but did not seem to differ in number of harvested lymph nodes , operation time , blood loss , numbers of patients needing transfusion , and reoperation rate . | {
"id": "C0024204",
"pos": [
143,
154
],
"name": "lymph nodes"
} | {
"id": "C0019080",
"pos": [
174,
184
],
"name": "blood loss"
} | 0NA
|
The damage of pancreatic beta cells was evaluated by TUNEL staining and immunofluorescence . | {
"id": "C0010957",
"pos": [
4,
10
],
"name": "damage"
} | {
"id": "C0016318",
"pos": [
72,
90
],
"name": "immunofluorescence"
} | 0NA
|
Renal mass was reduced by unilateral nephrectomy and ligation of 4 of the 6 terminal renal artery branches of the opposite kidney . | {
"id": "C0022646",
"pos": [
123,
129
],
"name": "kidney"
} | {
"id": "C0262613",
"pos": [
0,
10
],
"name": "Renal mass"
} | 11finding_site_of
|
Each mandible received cylindrical screw implants of 3.25 mm in diameter and 10 mm in length . | {
"id": "C0021102",
"pos": [
41,
49
],
"name": "implants"
} | {
"id": "C0024687",
"pos": [
5,
13
],
"name": "mandible"
} | 0NA
|
Paradoxically , the development of insulin resistance in the liver is not universal , but pathway selective , such that insulin fails to suppress gluconeogenesis but promotes lipogenesis , contributing to the hyperglycemia , steatosis , and hypertriglyceridemia that underpin the deteriorating glucose control and microvascular complications in T2D . | {
"id": "C0023884",
"pos": [
61,
66
],
"name": "liver"
} | {
"id": "C0020456",
"pos": [
209,
222
],
"name": "hyperglycemia"
} | 0NA
|
The accidents are analysed in aortography , in arterial catheterization using femoral or axillary arteries : the latter is the most dangerous . | {
"id": "C0015811",
"pos": [
78,
85
],
"name": "femoral"
} | {
"id": "C0003515",
"pos": [
30,
41
],
"name": "aortography"
} | 0NA
|
The RR of a positive challenge test to a non-selective COX-2 inhibitor was significant in patients who had a history of reaction to an analogous compound ( P 0.21 , OR 1.31 , RR 1.26 ) . | {
"id": "C1446409",
"pos": [
12,
20
],
"name": "positive"
} | {
"id": "C1257954",
"pos": [
55,
70
],
"name": "COX-2 inhibitor"
} | 0NA
|