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Bolasterone (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name) (brand names Myagen, Methosarb; former developmental code name U-19763), also known as 7α,17α-dimethyltestosterone, is a 17α-alkylated androgen/anabolic steroid (AAS) which is used in veterinary medicine. It has close structural similarity to testosterone, and like methyltestosterone has a methyl group at C17α in order to increase oral bioavailability. In addition, it is also 7α-methylated, similar to its 7β-methylated isomer calusterone. The medication has a low to moderate ratio of anabolic to androgenic activity, similar to that of fluoxymesterone. Bolasterone is on the World Anti-Doping Agency's list of prohibited substances, and is therefore banned from use in most major sports.
硒酸是一种无机酸,化学式为H2SeO4。它是硒的含氧酸,它的结构可以更准确地被描述为(HO)2SeO2。 根据价层电子对互斥理论的推测,中心的硒是四面体的,其中Se-O键长为161pm。它在固态为斜方晶系的晶体。
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Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock itch. It can be taken by mouth or applied as a cream to the skin or in the vagina. Common side effects when taken by mouth include nausea and itchiness. When applied to the skin, common side effects include redness and a burning sensation. In pregnancy, use on the skin or in the vagina is believed to be safe. There is no evidence of harm when used by mouth during pregnancy but this has been less well studied. When used by mouth, greater care should be taken in those with liver problems. It is in the azole class of medications and works by disrupting the fungal cell membrane. Clotrimazole was discovered in 1969. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2021, it was the 273rd most commonly prescribed medication in the United States, with more than 900,000 prescriptions.
芝麻林素(英語:Sesamolin)是一种木脂素类化合物,分子式C20H18O7,最早从芝麻油中分离。芝麻林素和芝麻素都是芝麻油中含有的微量成分,平均只占芝麻油质量的0.14%。
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Maltotriose is a trisaccharide (three-part sugar) consisting of three glucose molecules linked with α-1,4 glycosidic bonds. It is most commonly produced by the digestive enzyme alpha-amylase (a common enzyme in human saliva) on amylose in starch. The creation of both maltotriose and maltose during this process is due to the random manner in which alpha amylase hydrolyses α-1,4 glycosidic bonds. It is the shortest chain oligosaccharide that can be classified as maltodextrin.
1-溴丙烷为无色或淡黄色透明液体,中性或微酸性,对光敏感,m.p.-110℃,b.p.71℃,相对密度1.357(20℃),n20D为1.4341,能以任意比例与醇、醚混合,微溶于水。1-溴丙烷作为一种有机合成原料,在农药上用于合成有机磷杀虫杀螨剂硫丙磷、丙硫磷、丙溴磷等,也可用于医药、染料、香料工业,以及作为格氏试剂原料,CAS號為106-94-5 。
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Allantoic acid is a natural product found in Ilex paraguariensis, Arabidopsis thaliana, and other organisms with data available.
道諾黴素(英語:Daunorubicin,也可寫為daunomycin),是一種用於治療癌症的化療藥物。特別在治療急性骨髓性白血病 (AML)、急性淋巴性白血病 (ALL)、慢性髓細胞性白血病 (CML) 和卡波西肉瘤。它經靜脈注射給藥。也有一名為利泊桑體道諾黴素的脂質體形式的製劑販售。 道諾黴素屬於蒽環類藥物家族。它的部分作用是阻斷拓撲異構酶 II的功能。此藥物最初是從鏈黴菌屬中的細菌中分離而來。
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Thiodiglycol is a natural product found in Euglena gracilis with data available.
乙拉西坦(英語:Etiracetam)是含氮有机化合物,化学式C8H14N2O2,化学名α-乙基-2-氧-1-吡咯烷乙酰胺,属于拉西坦类药物,由比利时优时比(UCB Pharma)开发的一款促智药。其有两种对映体:左旋体的S-乙拉西坦和右旋体的R-乙拉西坦,然而只有左旋体——左乙拉西坦有生理活性,现已作为抗癫痫药销售;右旋体无活性。两种对映体在甲醇溶液中转变温度为30°C。
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2,3-Dihydroxybenzoic acid is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta. It is also abundant in the fruits of Flacourtia inermis. It is a dihydroxybenzoic acid, a type of organic compound. The colorless solid occurs naturally, being formed via the shikimate pathway. It is incorporated into various siderophores, which are molecules that strongly complex iron ions for absorption into bacteria. 2,3-DHB consists of a catechol group, which upon deprotonation binds iron centers very strongly, and the carboxylic acid group by which the ring attaches to various scaffolds through amide bonds. A famous high affinity siderophore is enterochelin, which contains three dihydroxybenzoyl substituents linked to the depsipeptide of serine. It is a potentially useful iron-chelating drug and has antimicrobial properties. 2,3-Dihydroxybenzoic acid is also a product of human aspirin metabolism.
三氟化氮(NF3)是卤化氮中最稳定的无机化合物,可在铜的催化下由氨气与氟气制成。 它可以用作氟化氢激光器的氧化剂,半导体、液晶和薄膜太阳能电池生产过程中的蚀刻剂。曾被试做火箭燃料。 但由于三氟化氮属于温室气体,能加剧温室效应,因此有人认为应该限制这种化合物的使用。
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Spermidine is a triamine that is the 1,5,10-triaza derivative of decane. It has a role as a fundamental metabolite, a geroprotector and an autophagy inducer. It is a triamine and a polyazaalkane. It is a conjugate base of a spermidine(3+).
常見的副作用包含恶心、呕吐、腹瀉及食慾不振,也可能引發過敏反應或一種腹瀉疾病--偽膜性結腸炎, 目前未能斷言對母乳餵養 患者是否有不良影響,但目前看來傾向於無虞;對懷孕患者則未發現不良影響。阿奇黴素是Azalide藥物,屬於一種大環內酯的抗細菌藥,藉由降低蛋白質生成以抑制細菌增殖。 1980年阿奇黴素問世 ,並在世界卫生组织基本药物标准清单登錄有案,作為通用名药物的價格也十分親民 ,一劑批發價約在0.18-2.98美元左右;在美國,截止2018年的每疗程花费约为4美元。
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Sulfanilic acid is a natural product found in Apis cerana with data available.
2-甲基戊烷是一种支链烷烃,又稱做異己烷,具有分子式C6H14。它可由4-甲基-2-戊酮的催化加氢反应制得。
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Cumene (isopropylbenzene) is an organic compound that contains a benzene ring with an isopropyl substituent. It is a constituent of crude oil and refined fuels. It is a flammable colorless liquid that has a boiling point of 152 °C. Nearly all the cumene that is produced as a pure compound on an industrial scale is converted to cumene hydroperoxide, which is an intermediate in the synthesis of other industrially important chemicals, primarily phenol and acetone (known as the cumene process).
2 Na + n Se → Na2Sen Na2Sen + 2 R4NCl → (R4N)2Sen + 2 NaCl
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Myrcene is a natural product found in Camellia sinensis, Artemisia thuscula, and other organisms with data available.
莨菪鹼(英語:hyoscyamine)又称曼陀罗素(daturine)、软木茄素(duboisine)、天仙子胺,是从茄科植物莨菪(Hyoscyamus niger)中分离得到的莨菪烷类生物碱,属于一种副交感神经抑制剂。
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5-Hydroxyferulic acid is a natural product found in Zea mays, Hordeum vulgare, and other organisms with data available.
二苯胺,化学式(C6H5)2NH,纯品为白色单斜片状结晶,但常因氧化而发黄。有毒。
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Tyramine is a natural product found in Magnolia officinalis, Senegalia berlandieri, and other organisms with data available.
丁香脂素(英語:Syringaresinol)是一种有机化合物,分子式C22H26O8,属于一种木脂素,存在于Castela emoryi(Castela emoryi)、梅(Prunus mume)等植物中。
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Stanozolol is an organic heteropentacyclic compound resulting from the formal condensation of the 3-keto-aldehyde moiety of oxymetholone with hydrazine. Like oxymetholone, it is a synthetic anabolic steroid. It has both anabolic and androgenic properties, and has been used to treat hereditary angioedema and various vascular disorders. It has also been widely abused by professional athletes. It has a role as an androgen and an anabolic agent. It is a 17beta-hydroxy steroid, a tertiary alcohol, an anabolic androgenic steroid and an organic heteropentacyclic compound. It is functionally related to an oxymetholone.
庚二酸(英語:heptanedioic acid,也称为薄桃酸,Pimelic acid)是一种二羧酸,化学式HOOC(CH2)5COOH,可由环己酮或水楊酸合成。
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Trifluridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-trifluoromethyluracil as the nucleobase. An antiviral drug used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis. It has a role as an antiviral drug, an antimetabolite, an EC 2.1.1.45 (thymidylate synthase) inhibitor and an antineoplastic agent. It is a nucleoside analogue, an organofluorine compound and a pyrimidine 2'-deoxyribonucleoside.
二甲卡因(英語:Dimethocaine 或 larocaine,缩写DMC)是一种含氮有机化合物,化学式C16H26N2O2,是可卡因的类似物。
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Cyclohexanone is a natural product found in Gymnodinium nagasakiense, Zingiber mioga, and other organisms with data available.
玫瑰醚(英語:Rose oxide),又称氧化玫瑰。是一种具有香味的吡喃单萜衍生物,天然存在于保加利亚玫瑰油、留尼汪香叶油中,化学式C10H18O,常作为香精运用于化妆品以及食品中。
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Afloqualone is an organic molecular entity.
母菊薁(英語:Chamazulene,化学名:1,4-二甲基-7-乙基薁)是一种带有芳香性的有机化合物,分子式C14H16,存在于德國洋甘菊(Matricaria chamomilla)、中亚苦蒿(Artemisia absinthium)、歐蓍草(Achillea millefolium)等菊科植物中。
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Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals, and in birth control pills. It is formulated and used both alone and in combination with an estrogen. CPA is taken by mouth one to three times per day. Common side effects of high-dose CPA in men include gynecomastia (breast development) and feminization. In both men and women, possible side effects of CPA include low sex hormone levels, reversible infertility, sexual dysfunction, fatigue, depression, weight gain, and elevated liver enzymes. At very high doses in older individuals, significant cardiovascular complications can occur. Rare but serious adverse reactions of CPA include blood clots, liver damage and brain tumors. CPA can also cause adrenal insufficiency as a withdrawal effect if it is discontinued abruptly from a high dosage. CPA blocks the effects of androgens such as testosterone in the body, which it does by preventing them from interacting with their biological target, the androgen receptor (AR), and by reducing their production by the gonads, hence their concentrations in the body. In addition, it has progesterone-like effects by activating the progesterone receptor (PR). It can also produce weak cortisol-like effects at very high doses. CPA was discovered in 1961. It was originally developed as a progestin. In 1965, the antiandrogenic effects of CPA were discovered. CPA was first marketed, as an antiandrogen, in 1973, and was the first antiandrogen to be introduced for medical use. A few years later, in 1978, CPA was introduced as a progestin in a birth control pill. It has been described as a "first-generation" progestin and as the prototypical antiandrogen. CPA is available widely throughout the world. An exception is the United States, where it is not approved for use.
己烯雌酚(英語:Diethylstilbestrol),简称DES,是一种非甾体雌激素类药物,目前很少使用。 在过去,它被广泛用于各种适应症,包括为有反复流产史的人提供妊娠支持,为更年期症状和雌激素缺乏提供激素治疗,治疗前列腺癌和乳腺癌,以及其他用途。 到2007年,它只用于前列腺癌和乳腺癌的治疗。 2011年,胡佛(Hoover)和他的同事报告了与DES相关的不良健康后果,包括不孕不育、流产、宫外孕、先兆子痫、早产、死產、婴儿死亡、更年期提前(45岁)、乳腺癌、宫颈癌和阴道癌。 虽然DES最常见的途径是口服,但也可用于其他途径,例如阴道塞剂、皮肤和注射。 己烯雌酚是一种雌激素,或雌激素受体的激动剂,是雌激素(如雌二醇)的靶标。 它是乙烯雌酚的一种人工合成的非甾体雌激素,与天然雌激素(如雌二醇)有许多不同之处。 与雌二醇相比,己烯雌酚口服后的生物利用度大大提高,对新陈代谢的抵抗力更强,在肝脏和子宫等身体某些部位表现出相对增强的效果。 这些差异导致DES有更高的血栓、心血管问题和某些其他不良反应的风险。 己烯雌酚于1938年被发现,并于1939年作为医疗用途。 从大约1940年到1971年,这种药物被给予孕妇,因为她们错误地认为它可以降低怀孕并发症和流产的风险。 1971年,在子宫内接触过这种药物的人中,DES被证明会导致透明细胞癌,这是一种罕见的阴道肿瘤。 美国食品和药物管理局随后撤回了对DES作为孕妇治疗方法的批准。 后续研究表明,DES还有可能在接触者的有生之年造成各种严重的不良并发症。 美国国家癌症研究所建议 服用己烯雌酚的母亲所生的孩子定期接受特别的体检,以筛查这种药物造成的并发症。在母亲怀孕期间接触DES的人通常被称为“DES女儿”和“DES儿子”。 自从发现DES的毒性作用以来,它现在基本已经停产,不在市面销售。
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Aldosterone is a pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. It has a role as a human metabolite and a mouse metabolite. It is an 11beta-hydroxy steroid, a 21-hydroxy steroid, a 18-oxo steroid, a 20-oxo steroid, a C21-steroid hormone, a steroid aldehyde, a 3-oxo-Delta(4) steroid, a primary alpha-hydroxy ketone and a mineralocorticoid. It derives from a hydride of a pregnane.
莽草酸(3,4,5-三羟基-1-环己烯-1-甲酸)是一种易溶于水的白色晶体粉末。它因最早分离自日本莽草而得名,是一种植物和微生物的重要代谢产物。
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Propane () is a three-carbon alkane with the molecular formula C3H8. It is a gas at standard temperature and pressure, but compressible to a transportable liquid. A by-product of natural gas processing and petroleum refining, it is often a constituent of liquefied petroleum gas (LPG), which is commonly used as a fuel in domestic and industrial applications and in low-emissions public transportation; other constituents of LPG may include propylene, butane, butylene, butadiene, and isobutylene. Discovered in 1857 by the French chemist Marcellin Berthelot, it became commercially available in the US by 1911. Propane has lower volumetric energy density than gasoline or coal, but has higher gravimetric energy density than them and burns more cleanly. Propane gas has become a popular choice for barbecues and portable stoves because its low −42 °C boiling point makes it vaporise inside pressurised liquid containers (it exists in two phases, vapor above liquid). It retains its ability to vaporise even in cold weather, making it better-suited for outdoor use in cold climates than alternatives with higher boiling points like butane. LPG powers buses, forklifts, automobiles, outboard boat motors, and ice resurfacing machines, and is used for heat and cooking in recreational vehicles and campers. Propane is becoming popular as a replacement refrigerant (R290) for heatpumps also as it offers greater efficiency than the current refrigerants: R410A / R32, higher temperature heat output and less damage to the atmosphere for escaped gasses - at the expense of high gas flammability.
芬布芬(Fenbufen)是一种非類固醇消炎止痛藥,主要用于治疗骨关节炎、脊柱关节疾患、類风湿性关节炎、肌腱炎等,亦可用于缓解背痛、牙痛、手术后疼痛及外伤性疼痛。芬布芬以胶囊或片剂形式出售。芬布芬抑制环氧酶的活性以减少前列腺素而起作用。动物实验证明,芬布芬抗炎镇痛作用比吲哚美辛弱,但比阿司匹林强。
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Molybdenum hexafluoride, also molybdenum(VI) fluoride, is the inorganic compound with the formula MoF6. It is the highest fluoride of molybdenum. It is a colourless solid and melts just below room temperature and boils in 34 °C. It is one of the seventeen known binary hexafluorides.
山羊豆碱(英語:Galegine)是一种胍类化合物,分子式C6H13N3,有一定毒性,存在于山羊豆(Galega officinalis)中
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Terephthalic acid is a benzenedicarboxylic acid carrying carboxy groups at positions 1 and 4. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and isophthalic acids. It is a conjugate acid of a terephthalate(1-).
异丁酸甲酯是一种具示性式(CH3)2CHC(O)OCH3之有机化合物 。其為異丁酸之甲醇酯,在常溫常壓下為無色液體,常被用為溶剂。
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Biphenyl is a benzenoid aromatic compound that consists of two benzene rings connected by a single covalent bond. Biphenyl occurs naturally in coal tar, crude oil, and natural gas. Formerly used as a fungicide for citrus crops. It has a role as an antimicrobial food preservative and an antifungal agrochemical. It is a member of benzenes, an aromatic fungicide and a member of biphenyls.
乙二胺(作為配體時簡稱為en)是化學式為 C2H4(NH2)2 的有機化合物。乙二胺是一種胺類,為無色的鹼性液體,有類似氨的臭味。2008年乙二胺的使用量約500,000,000公斤。
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Nevirapine is a dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection. It has a role as an antiviral drug and a HIV-1 reverse transcriptase inhibitor. It is a dipyridodiazepine and a member of cyclopropanes.
它和其它异氰酸酯一样,可以和胺反应,生成脲;它和醇反应,生成氨基甲酸酯。它和三乙胺一起使用,活化硝基,进行(C,O) 1,3-偶极环加成反应(对比O,O),反应中硝基(RCH2NO2)转化为RCNO,并产生CO2。
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Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. It has a role as an antihypertensive agent, a first generation antipsychotic, an adrenergic uptake inhibitor, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor, an environmental contaminant, a xenobiotic and a plant metabolite. It is an alkaloid ester, a methyl ester and a yohimban alkaloid. It is functionally related to a reserpic acid.
利血平(英語:Reserpine),或作利舍平,蛇根碱,是一种用于治疗高血压及精神病的吲哚类生物碱药物,最初是在萝芙木属植物蛇根木中提煉而成。如今由于副作用较多并且更优的新药上市,利血平已不再是治疗的首选药物。儿茶酚胺类(属于单胺类神经递质)在对心率、心肌收缩力和外周阻力的调控上有著极大作用,利血平的降压作用是透過消耗外周交感神经末梢的儿茶酚胺而发挥药效。
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Tebuthiuron is an organonitrogen heterocyclic compound and an organosulfur heterocyclic compound.
双己维林(英語:Dihexyverine,商品名:Spasmodex)是一种含氮有机化合物,分子式C20H35NO2,可作为抗膽鹼劑和解痙藥。
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Perfluoroheptane, C7F16, (usually referring to the straight chain molecule called n-perfluoroheptane) is a perfluorocarbon. It is hydrophobic (water-insoluble) and oleophobic (oil-insoluble). It is used in deacidification of paper as a medium carrying powdered magnesium oxide.
茶痂衣酸(英語:Psoromic acid)是一种有机化合物,化学式C18H14O8,属于一种缩酚酸环醚,可抑制一型与二型单纯疱疹病毒。
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Methyl isothiocyanate is the organosulfur compound with the formula CH3NS. This low melting colorless solid is a powerful lachrymator. As a precursor to a variety of valuable bioactive compounds, it is the most important organic isothiocyanate in industry.
磺胺多辛是一种磺胺类药物,其INN名称是“Sulfadoxine”。该药物可用于治疗疟疾等病症。该药物在血液中的半衰期暂时未知,在大鼠体内的LD50(半致死量)为1.8756mol/kg。该药物目前已不再单独使用。
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Methandriol dipropionate is a steroid ester.
焦亚硫酸,严格地说是偏二亚硫酸,是一种硫的含氧酸,化学式为H2S2O5。焦亚硫酸和硫代硫酸一样,不能以游离态存在。与焦硫酸不同的是其中两个硫原子直接相连。
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Gentianine is a pyridine-derived alkaloid. Originally isolated in 1944 from Gentiana kirilowi, it has also been found in Gentiana macrophylla, fenugreek, Strychnos angolensis, Strychnos xantha, and other plants. Gentianine is a crystalline solid with a melting point of 82-83 °C. It is a base that forms salts, such as the hydrochloride salt, upon treatment with acids. Gentianine has been studied for its potential anti-inflammatory properties.
龙胆碱(英語:Gentianine),又称龙胆宁或秦艽甲素,旧称秦艽生物碱甲,是一种吡啶生物碱,化学式为C10H9NO2,存在于秦艽(学名:Gentiana macrophylla)等植物中。
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Monobenzyl phthalate (MBzP) also known as 1,2-Benzenedicarboxylic acid, 1-(phenylmethyl) ester is an organic compound with the condensed structural formula C6H5CH2OOCC6H4COOH. It is the major metabolite of butyl benzyl phthalate(BBP), a common plasticizer. BBP can also be metabolized into monobutyl phthalate (MBP). Like many phthalates, BBP has attracted attention as a potential endocrine disruptor.
邻苯二甲酸单苄酯(英語:Monobenzyl phthalate,缩写MBzP,IUPAC名为2-苯甲氧基羰基苯甲酸,2-phenylmethoxycarbonylbenzoic acid)是一种结构简式为C6H5CH2OOCC6H4COOH的有机化合物。MBzP为邻苯二甲酸丁苄酯在人体内的主要初级代谢产物,多于另一种水解产物邻苯二甲酸单丁酯 (MBP)。和其它许多邻苯二甲酸酯一样,MBzP也是一种内分泌干扰物。
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Piperazine () is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. Piperazine exists as small alkaline deliquescent crystals with a saline taste. The piperazines are a broad class of chemical compounds, many with important pharmacological properties, which contain a core piperazine functional group.
芬太尼(英語:fentanyl)是一種強效的類鴉片止痛劑,起效迅速而作用時間極短。它是腦中μ-鴉片受體的強力激動劑。芬太尼比嗎啡效力高50至100倍。但一些為了模擬芬太尼之藥理作用的芬太尼類似物可能比嗎啡高出10,000倍,如 Carfentanil。如過量使用,嚴重者將會引發呼吸困難死亡。
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Thiocyanogen is an organic disulfide and a pseudohalogen.
霜霉威(英语:Propamocarb,缩写PM),学名3-(二甲基氨基 )丙基氨基甲酸丙酯,是一种农业灭真菌剂,化学式:C9H20N2O2,常以盐酸盐水剂和喷剂形式用于受水霉感染的土壤、根、叶消杀。
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In organic chemistry, phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2 and structure HO(O)C−C6H4−C(O)OH. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Phthalic acid is one of three isomers of benzenedicarboxylic acid, the others being isophthalic acid and terephthalic acid.
三苔色酸(英語:Gyrophoric acid,也译为石耳酸)是一种有机化合物,分子式C24H20O10,属于三缩酚酸,存在于隐囊衣属、黄梅属等真菌以及疱脐衣属、石耳屬等地衣中。过去三苔色酸曾被视为是一种二缩酚酸,直到1925年确定其结构后才发现其分子由三个苔色酸(orsellinic acid)组成,且在地衣体内由二缩酚酸红粉苔酸转化得到,系一种三缩酚酸。
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Chlorothalonil is a dinitrile that is benzene-1,3-dicarbonitrile substituted by four chloro groups. A non-systemic fungicide first introduced in the 1960s, it is used to control a range of diseases in a wide variety of crops. It has a role as an antifungal agrochemical. It is a dinitrile, a tetrachlorobenzene and an aromatic fungicide. It is functionally related to an isophthalonitrile.
丹皮酚(paeonol)是在芍药属植物(如牡丹)、 一把伞南星和日本薯蓣中发现的一种酚类化合物。它是某些中药中的成分。
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Methyl benzoate is an organic compound. It is an ester with the chemical formula C6H5COOCH3, sometimes abbreviated as PhCO2Me, where Ph and Me are phenyl and methyl, respectively. Its structure is C6H5−C(=O)−O−CH3. It is a colorless liquid that is poorly soluble in water, but miscible with organic solvents. Methyl benzoate has a pleasant smell, strongly reminiscent of the fruit of the feijoa tree, and it is used in perfumery. It also finds use as a solvent and as a pesticide used to attract insects such as orchid bees.
乙胺嗪 (英語:Diethylcarbamazine,簡稱DEC)是一種用於治療絲蟲病(包括淋巴絲蟲病、熱帶肺嗜酸性粒細胞增多症和羅阿絲蟲病)的藥物。它也可為高危險群作預防感染羅阿絲蟲病之用。雖然此藥物已用於治療蟠尾絲蟲症(即河盲症),但屬於阿維菌素家族的伊維菌素才是首選藥物。此藥物透過口服方式給藥。 乙胺嗪於1947年由印度裔美國籍生物化學家Yellapragada Subbarow發現,已被納入世界衛生組織基本藥物標準清單之中。乙胺嗪並未在美國上市,但可從美國疾病管制與預防中心(CDC)取得。
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Ethylamine, also known as ethanamine, is an organic compound with the formula CH3CH2NH2. This colourless gas has a strong ammonia-like odor. It condenses just below room temperature to a liquid miscible with virtually all solvents. It is a nucleophilic base, as is typical for amines. Ethylamine is widely used in chemical industry and organic synthesis. It is a DEA list I chemical by 21 CFR § 1310.02.
Br2(l) + H2O(l) ↔ HBrO(aq) + HBr (aq)
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Dodecane is a straight-chain alkane with 12 carbon atoms. It has been isolated from the essential oils of various plants including Zingiber officinale (ginger). It has a role as a plant metabolite.
异戊烷(英語:Isopentane)是一种分子式为C5H12的烷烃,与正戊烷、新戊烷互为同分异构体。
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Isoxazole is a monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles. It is a mancude organic heteromonocyclic parent, a monocyclic heteroarene and a member of isoxazoles.
美金刚胺(Memantine)是用于减缓中度至重度阿尔茨海默症进展的药物,通过口服使用。 美金刚胺的常见副作用包括头痛、便秘、嗜睡和头晕,严重的副作用可能包括血栓、精神病和心力衰竭。它的作用机理认为是阻挡N-甲基-D-天冬氨酸受体。 在美国于2003年批准用于美金刚胺医疗用途。它可作为通用名药物使用。2019年,美金刚胺是美国第169常用的处方药,有超过三百万张处方。
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Longifolene is a sesquiterpene.
3-己醇,是一種醇類的有機化合物,是在三號碳上接羥基的己醇。它的化學式是C6H13OH、示性式是C3H7CH(OH)C2H5,是正己醇的一種異構物。 3-己醇有一個手性中心,故存在光學異構物。 3-己醇聞起來有香氣,常在香蕉、葡萄柚、甜瓜 等植物中找到。高濃度的3-己醇对水稍微有危害的,不能傾倒於地下水或污水系统,需放入廢液桶回收處理。
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Catechol ( or ), also known as pyrocatechol or 1,2-dihydroxybenzene, is an organic compound with the molecular formula C6H4(OH)2. It is the ortho isomer of the three isomeric benzenediols. This colorless compound occurs naturally in trace amounts. It was first discovered by destructive distillation of the plant extract catechin. About 20,000 tonnes of catechol are now synthetically produced annually as a commodity organic chemical, mainly as a precursor to pesticides, flavors, and fragrances. Small amounts of catechol occur in fruits and vegetables.
胱氨酸(Cystine),学名“二(β-硫-α-氨基丙酸)”,是两分子半胱氨酸经氧化得到的氨基酸,是一种含硫氨基酸,属于二硫化物类。
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Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old. Side effects may include liver problems. It has a multifactorial mode of action and is characterized by a fast onset of action. It works by blocking the production of prostaglandins (a chemical associated with pain), thereby relieving pain and inflammation.
布马佐辛(INN:bremazocine)是一种含氮有机化合物,分子式C20H29NO2,属喷他佐辛的结构类似物,可作为镇痛药和利尿劑,1984年确定其化学结构。
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Selenide is a natural product found in Homo sapiens with data available.
甲基丙烯酸甲酯(methyl methacrylate, MMA)是一种有机物,分子式为CH2=C(CH3)COOCH3,无色液体,是将甲基丙烯酸(MAA)与甲醇酯化形成的,它是生产透明塑料聚甲基丙烯酸甲酯(PMMA)的单体。
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Karanjin is an extended flavonoid.
状芸香素(英語:Chalepensin)是一种呋喃香豆素类化合物。该化合物最初于1967年从叙利亚芸香(Ruta chalepensis)中分离出来,并由此得名。在芸香属的其他植物中也发现了这种物质,包括芸香和山芸香。
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Cabergoline, sold under the brand name Dostinex among others, is a dopaminergic medication used in the treatment of high prolactin levels, prolactinomas, Parkinson's disease, and for other indications. It is taken by mouth. Cabergoline is an ergot derivative and a potent dopamine D2 receptor agonist. Cabergoline was patented in 1980 and approved for medical use in 1993. It is on the World Health Organization's List of Essential Medicines.
全氟己烷磺酸(英語:Perfluorohexanesulfonic acid,缩写PFHxS,共軛酸鹼對为全氟己烷磺酸根,perfluorohexanesulfonate)是一种人造的含氟表面活性剂和持久性有機污染物。
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Phenylpropiolic acid, C6H5CCCO2H, formed by the action of alcoholic potash on cinnamic acid dibromide, C6H5CHBrCHBrCO2H, crystallizes in long needles or prisms which melt at 136–137 °C. When heated with water to 120 °C, it yields phenylacetylene (C6H5CCH). Chromic acid oxidizes it to benzoic acid; zinc and acetic acid reduce it to cinnamic acid, C6H5CH=CHCO2H, whilst sodium amalgam reduces it to hydrocinnamic acid, C6H5CH2CH2CO2H. Ortho-nitrophenylpropiolic acid, NO2C6H4CCCO2H, prepared by the action of alcoholic potash on ortho-nitrocinnamic acid dibromide, crystallizes in needles which decompose when heated to 155–156 °C. It is readily converted into indigo.
變腎上腺素 (Metanephrine, metadrenaline) 是腎上腺素經由儿茶酚-O-甲基转移酶(COMT)作用後產生的代謝產物。
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Blasticidin S is a blasticidin that is an antibiotic obtained from Streptomyces griseochromogene. It has a role as a fungicide, a bacterial metabolite, an antimicrobial agent and a protein synthesis inhibitor. It is an antibiotic antifungal agent and a blasticidin. It is a conjugate base of a blasticidin S(1+).
3-羟基辛酸(英語:3-Hydroxyoctanoic acid)是一种天然β-羟基酸,存在于人体与其它动物中,是G蛋白偶联受体羟基羧酸受体3(HCA3)的内源性激动剂。在植物中也有出现
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Methidathion is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an acaricide and an agrochemical. It is functionally related to a 5-methoxy-1,3,4-thiadiazol-2(3H)-one.
糠醇是有羟甲基取代的呋喃衍生物,是无色液体,但放置過久的試樣呈琥珀色,有微弱的燃烧气味和苦味。可與水混溶但其溶液不稳定。也可溶于常見有机溶剂。
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Prontosil is an antibacterial drug of the sulfonamide group. It has a relatively broad effect against gram-positive cocci but not against enterobacteria. One of the earliest antimicrobial drugs, it was widely used in the mid-20th century but is little used today because better options now exist. The discovery and development of this first sulfonamide drug opened a new era in medicine, because it greatly widened the success of antimicrobial chemotherapy in an era when many physicians doubted its still largely untapped potential. At the time, disinfectant cleaners and topical antiseptic wound care were widely used but there were very few antimicrobial drugs to use safely inside living bodies. Antibiotic drugs derived from microbes, which are relied on heavily today, did not yet exist. Prontosil was discovered in 1932 by a research team at the Bayer Laboratories of the IG Farben conglomerate in Germany led by Gerhard Domagk. Domagk received the 1939 Nobel Prize in Physiology or Medicine for that discovery.
赛洛唑啉(英文:Xylometazoline,也拼作xylomethazoline),是一种用于减轻鼻塞、过敏性鼻炎和鼻窦炎症状的药物。 不建议使用超过七天。同样,不建议三个月以下的婴儿使用,有的说法甚至建议不要在6岁以下儿童使用。 这种药物是直接通过鼻子作为喷雾或滴剂使用的。 副作用包括失眠、鼻子刺激、恶心、鼻出血(3%)、月经疼痛(10%)和头痛(3%)。 长期使用(>10天)不推荐,因为停用后可能会出现药物性鼻炎。不建议在怀孕期间使用。赛洛唑啉属于减充血剂和α肾上腺素受体激动剂这两类药物。
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Sarcosine is a N-alkylglycine that is the N-methyl derivative of glycine. It is an intermediate in the metabolic pathway of glycine. It has a role as a glycine transporter 1 inhibitor, a glycine receptor agonist, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a N-alkylglycine, a N-methyl-amino acid and a member of N-methylglycines. It is a conjugate base of a sarcosinium. It is a conjugate acid of a sarcosinate. It is a tautomer of a sarcosine zwitterion.
枯茗醛,也称4-异丙基苯甲醛,是一种由植物中提取出的有机天然产物。它的分子式为C10H12O,结构上为苯甲醛的对位被异丙基取代。枯茗醛是一些常见香料(如桉树、没药、桂皮与孜然)等香料精油的重要组分,具有一种令人愉悦的气味。其名來自孜然的英語 cumin,上述几类精油的芳香气味亦与其有关。因此枯茗醛常作为香水与化妆品的添加剂使用。
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Morinamide is a member of pyrazines, a secondary carboxamide and a member of morpholines.
治螟磷或硫特普(英語:Sulfotep),化学名二硫代焦磷酸四乙酯或四乙基二硫代焦磷酸酯(英語:tetraethyldithiopyrophosphate,缩写TEDP)是一种具有触杀、内吸和熏蒸作用的有机磷杀虫剂,常温下为具有类似大蒜气味的淡黄色油状液体,属于高毒农药。其对昆虫具有胆碱能性效果,通过抑制昆虫周围神经和中枢神经系统胆碱酯酶活性,干扰突触利用乙酰胆碱的信号通路来达到灭虫效果。截止至2017年,除巴西等少数国家外,因其急性毒性已被欧盟、美国和中国等多个国家禁止作为杀虫剂使用。
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Kainic acid is a natural product found in Digenea simplex, Apis cerana, and other organisms with data available.
錦葵素-3-O-葡萄糖苷(英語:Oenin;Malvidin 3-O-glucoside)(法語:Œnine;Malvidine-3-O-glucoside)是锦葵花素的3-葡萄糖苷。紫色葡萄和葡萄酒當中含有它,同時它也是紅葡萄酒的紅色色素。
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Bromoform is a member of bromomethanes and a bromohydrocarbon.
溴仿(英語:Bromoform)是卤仿的一種,化学式為CHBr3,室温下为暗黄色的液体,有和氯仿类似的甜气味。它有限可溶于水,容易蒸发。折射率1.595(20°C、D),与乙醇、苯、氯仿、醚、石油醚、丙酮混溶,与水以1/800的比例溶解,少量自然存在于海洋植物中,进入环境中的溴仿大多是用氯气给水杀菌时的副产物。 溴仿可通过丙酮和次溴酸钠(溴与碱反应得到)发生卤仿反应、电解溴化钾的乙醇溶液或氯仿与溴化铝反应制取。 溴仿可作溶剂、选矿剂、镇静剂、阻燃剂、实验室试剂等。
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Azetidine is a saturated heterocyclic organic compound containing three carbon atoms and one nitrogen atom. It is a liquid at room temperature with a strong odor of ammonia and is strongly basic compared to most secondary amines.
1-壬烯(英語:1-Nonene),也称为正壬烯,结构简式CH2=CH(CH2)6CH3,是壬烯的同分异构体之一,其碳碳双键位于末端,因而不存在顺反异构。
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Cantharidin is an odorless, colorless fatty substance of the terpenoid class, which is secreted by many species of blister beetles. Its main current use in pharmacology is treating molluscum contagiosum and warts topically. It is a burn agent and poisonous in large doses, and has been historically used as aphrodisiacs (Spanish fly). In its natural form, cantharidin is secreted by the male blister beetle, and given to the female as a copulatory gift during mating. Afterwards, the female beetle covers her eggs with it as a defense against predators. Poisoning from cantharidin is a significant veterinary concern, especially in horses, but it can also be poisonous to humans if taken internally (where the source is usually experimental self-exposure). Externally, cantharidin is a potent vesicant (blistering agent), exposure to which can cause severe chemical burns. Properly dosed and applied, the same properties have also been used therapeutically, for instance, for treatment of skin conditions, such as molluscum contagiosum infection of the skin. Cantharidin is classified as an extremely hazardous substance in the United States, and is subject to strict reporting requirements by facilities that produce, store, or use it in significant quantities.
斑蝥素是一种有机化合物,为一种无味、无色的萜类脂肪物质,由多种芫菁科昆虫分泌。 它可以二甲基顺丁烯二酸酐和呋喃为原料反应,再经催化氢化制得。
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Acephate is a phosphoramide that is methamidophos in which one of the hydrogens is replaced by an acetyl group. It has a role as an acaricide, an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an agrochemical. It is a mixed diacylamine, a phosphoramide, an organic thiophosphate and an organothiophosphate insecticide. It is functionally related to a member of methamidophos.
甲基丙二酸 (Methylmalonic acid,MMA)是一种二羧酸,是丙二酸的甲基化衍生物,丁二酸(琥珀酸)的同分异构体。
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(S)-nicotine is a 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum. It has a role as a phytogenic insecticide, a teratogenic agent, a neurotoxin, an anxiolytic drug, a nicotinic acetylcholine receptor agonist, a biomarker, an immunomodulator, a mitogen, a peripheral nervous system drug, a psychotropic drug, a plant metabolite and a xenobiotic. It is a conjugate base of a (S)-nicotinium(1+). It is an enantiomer of a (R)-nicotine.
勃地酮或译为宝丹酮(英語:Boldenone,开发阶段代号为:RU-18761)也被称为Δ1-睾酮,Δ1-testosterone,是一种天然同化類固醇(AAS)和睾酮的 1(2)-脱氢产物。勃地酮本身并未作为医用藥品上市,但其十一酸酯——宝丹酮十一烯酸酯为已上市药物。
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Azulene is an aromatic organic compound and an isomer of naphthalene. Naphthalene is colourless, whereas azulene is dark blue. The compound is named after its colour, as "azul" is Spanish for blue. Two terpenoids, vetivazulene (4,8-dimethyl-2-isopropylazulene) and guaiazulene (1,4-dimethyl-7-isopropylazulene), that feature the azulene skeleton are found in nature as constituents of pigments in mushrooms, guaiac wood oil, and some marine invertebrates. Azulene has a long history, dating back to the 15th century as the azure-blue chromophore obtained by steam distillation of German chamomile. The chromophore was discovered in yarrow and wormwood and named in 1863 by Septimus Piesse. Its structure was first reported by Lavoslav Ružička, followed by its organic synthesis in 1937 by Placidus Plattner.
苄丙酮(IUPAC 名称:4-苯基丁-2-酮)是一种具有甜美花香气味的液体,被认为是花朵(例如菸草, Nicotiana attenuata ) 中最丰富的引诱剂化合物和可可的挥发性成分之一。 苄丙酮可用作瓜實蝇( Bactrocera cucurbitae )的引诱剂, 在香水中作添加劑, 以及用作肥皂的加味剂。
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Pyrrolidine is a cyclic amine whose five-membered ring contains four carbon atoms and one nitrogen atom; the parent compound of the pyrrolidine family. It is a saturated organic heteromonocyclic parent, a member of pyrrolidines and an azacycloalkane. It is a conjugate base of a pyrrolidinium ion.
吡咯烷(Pyrrolidine),又称四氫吡咯(Tetrahydropyrrole),是五元含氮的饱和杂环化合物。
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Scoparone is a natural product found in Saussurea eopygmaea, Cedrelopsis grevei, and other organisms with data available.
氨苄西林(英語:Ampicillin)是一種抗生素,屬於青黴素家族的氨基青黴素類,用於預防和治療多種細菌感染,如呼吸道感染、泌尿道感染、腦膜炎、沙門氏菌感染症和心內膜炎。它也用於預防新生兒B型鏈球菌感染。給藥方式有口服、肌肉注射或是靜脈輸注。 使用後常見的副作有皮疹、噁心和腹瀉。對青黴素過敏的人不宜使用。嚴重的副作用有艱難你梭菌結腸炎或過敏性休克。雖然有腎臟問題的個體可使用,但可能需要減少劑量。個體在懷孕期間使用對於胎兒,和在母乳哺育期間對於嬰兒似乎無安全的問題。 氨芐西林於1958年被發現,並於1961年進入醫療用途。它已被列入世界衛生組織基本藥物標準清單之中。]世界衛生組織(WHO)將此藥物列為對人類醫學非常重要的一種。市面上已有其通用名藥物流通。
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3-Indolepropionic acid (IPA), or indole-3-propionic acid, has been studied for its therapeutic value in the treatment of Alzheimer's disease. As of 2022 IPA shows potential in the treatment of this disease, though the therapeutic effect of IPA depends on dose and time of therapy initiation. Though promising in some historical clinical trials, IPA is not clinically listed as a useful therapeutic in managing Alzheimer's as of 2023. IPA is an even more potent scavenger of hydroxyl radicals than melatonin, the most potent scavenger of hydroxyl radicals that is synthesized by human enzymes. Similar to melatonin but unlike other antioxidants, it scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds.
己脒定(英语:Hexamidine)是一种防腐剂和消毒剂。己脒定的二羟乙基磺酸盐溶液(1/1.000)的商品名为Hexomedine。己脒定主要以其二羟乙磺酸盐的形式使用,它比二盐酸盐更易溶于水。 1939 年,May & Baker首次合成了二盐酸盐,并作为杀锥虫剂获得了专利。它的杀变形虫特性在1990年代发现。其杀菌作用的确切机制尚不清楚,但推测类似于季铵盐化合物,涉及与病原体带负电荷的脂质膜结合。己脒定及其较短的同类物普罗帕脒在药物和化妆品中用作防腐剂和保鲜剂。它们特别用于棘变形虫病(棘变形虫角膜炎)的局部治疗。
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1,9-Nonanediol is an aliphatic alcohol.
二氯乙炔(英語:Dichloroethyne 或 dichloroacetylene,缩写DCA)是一种有机氯化合物,化学式ClC≡CCl,常温常压下为无色液体,易燃易爆。
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Rishitin is a natural product found in Boeremia exigua, Boeremia foveata, and other organisms with data available.
PCl3 + 3H2O → H3PO3 + 3 HCl
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A pteridine is a bicyclic heterocyclic system with two nitrogen atoms at positions 1 and 4 in ring A, and two nitrogen atoms at positions 1 and 3 in ring B. Pteridines constitute a large group of heterocyclic compounds containing a wide variety of substituents on this parent structure. Pterins and flavins are classes of substituted pteridines that have diverse biological roles.
四硫富瓦烯(英語:Tetrathiafulvalene,缩写:TTF),是富瓦烯的2,2'-位被硫原子替换后形成的有机硫化合物,化学分子式(H2C2S2C)2。它最早由Wudl在1970年合成,1972年发现其氯化物盐具高导电性,次年制得其TCNQ盐,并发现该盐的导电性在室温以下突然增加,在60K可达10^4 ohm^(-1) cm^(-1),足以被称为“有机金属”。1979年又进一步发现以四硫富瓦烯为基础的Bechgaard盐[TMTSF]2X(X为PF6-,AsF6-)为首个制得的分子超导体,使得人们对这一领域产生极大兴趣。超过10,000个科学出版物讨论TTF及其衍生物。
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Panaxatriol is a triterpenoid saponin.
二没食子酸(英語:Digallic acid,或称为没食子酸-3-没食子酸酯Gallic acid 3-monogallate)是一种有机化合物,化学式C14H10O9,是没食子酸形成的缩酚酸,存在于乳香黃連木(Pistacia lentiscus)等植物中,是鞣酸生物合成的前体。
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Ethambutol is an ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone. It has a role as an antitubercular agent, an environmental contaminant and a xenobiotic. It is a member of ethanolamines and an ethylenediamine derivative.
護谷(英語:Nitrofen) 是種除草劑,在水田里普遍使用,為防治雜草叢生,由於毒性強烈,易使身孕者產生畸胎,而且中毒後造成的症狀有白血球跟血紅素降低,以及降低血清中的胆碱酯酶及过氧化氢酶的活性,已被一些国家或地区政府禁止在市场上销售。
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2-methyltridecane is a long-chain alkane that is tridecane substituted by a methyl group at position 2. Metabolite observed in cancer metabolism. It has a role as a human metabolite. It derives from a hydride of a tridecane.
2,4,6-三甲基吡啶是一种有机化合物,化学式为C8H11N。
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Methylamine is a natural product found in Homo sapiens, Fulica atra, and other organisms with data available.
甲萘氢醌(英語:Menadiol)是一种有机化合物,化学式C6H4(COH)2(CH)(CH3),带有对苯二酚结构,是维生素K4的成分之一,可被氧化成甲萘醌(维生素K3)。
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Formiminoglutamic acid is a natural product found in Daphnia pulex, Homo sapiens, and other organisms with data available.
二苯基砜(英語:Diphenyl sulfone)是一种有机硫化合物,化学式(C6H5)2SO2,常温常压下为白色固体,可溶于有机溶剂。二苯基砜可作为处理高刚性聚合物如聚醚醚酮(PEEK)的高温溶剂。
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Clevudine is a pyrimidine 2'-deoxyribonucleoside.
环苯扎林(英語:cyclobenzaprine)是一種肌肉鬆弛劑,用於治療突發性肌肉骨骼疾病引起的肌肉痙攣。對腦性麻痺沒有用處。是通過口服给药的。建議使用時間不要超過幾週。 常見的副作用包括頭痛、疲倦、頭暈和口乾。嚴重的副作用可能包括心跳不規則。沒有證據表明妊娠會造成傷害,但尚未在這一人群中進行充分研究。不得與MAO抑制劑一起使用。現時尚不清楚是如何運作的。 环苯扎林於1977年在美國被準予用於醫療用途。是一种通用名药物。在美國,截至2018年,每劑的批發成本不到0.05美元。2017年,环苯扎林是美國第43大最常見的處方藥,處方數量超過1700萬張。
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Bufuralol is a member of benzofurans.
环扁桃酯(英語:Cyclandelate)是一种有机化合物,化学式C17H24O3,属于一种血管扩张剂,用于治疗雷诺氏综合征、动脉硬化等。
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Daunosamine is a deoxy sugar and amino sugar of the hexosamine class. Daunosamine is a component of the anthracycline class of antineoplastics, linked to a derivative of naphthacene. It is a component of birch juice. The compound is soluble in water and responds with polymers like cellulose and lignin if it is in excess, so collection of birch juice is very helpful for the birch tree. The dnrQ gene is required for the synthesis of daunosamine.
2-乙酰基吡啶是一种有机化合物,化学式为CH3COC5H4N。其外观是粘稠无色液体,多见于麦芽,常用作香料,是爆米花、啤酒、墨西哥薄饼等食物的香味来源之一。2-乙酰基吡啶可通过美拉德反应和灰化产生。通过格氏试剂酰化2-溴吡啶可以制备2-乙酰基吡啶。
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Volemitol is a heptitol that is heptane-1,2,3,4,5,6,7-heptol that has R-configuration at positions 2, 3, 5 and 6. It has a role as a metabolite.
苯异丙肼(英語:Pheniprazine或amphethydrazine、amphetamine hydrazide,商品名:Catron、Cavodil,开发代号:JB-516)是一种有机化合物,化学式为C9H14N2,属于聯氨类单胺氧化酶抑制剂(MAOI),1960年代开始作为抗抑郁药使用。
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Alacepril is a thioacetate ester and a dipeptide. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor.
麥芽醇(英語:Maltol)是一種天然存在的有機化合物,主要用作香料。它存在於落葉松的樹皮、松針和烤麥芽中,由此得名。它是一種可溶於熱水、氯仿和其他極性溶劑的白色結晶粉末。由于麥芽醇具有棉花糖和焦糖的氣味,其可賦予香水甜味。麥芽酚的甜味可增加新鮮出爐麵包的香味,可在麵包和蛋糕中用作增味劑(INS編號636)。 麥芽酚與相關的3-羥基-4-吡喃酮化合物(如麴酸)可与硬的金属离子,如Fe3+、Ga3+、Al3+、VO2+配位,因此可用于增加体内铝的摄取量,也用于增加镓和铁的口服生物利用度。它的食品添加劑E編號為E636。
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Hematoporphyrin (Photodyn, Sensibion) is a porphyrin prepared from hemin. It is a derivative of protoporphyrin IX, where the two vinyl groups have been hydrated (converted to alcohols). It is a deeply colored solid that is usually encountered as a solution. Its chemical structure was determined in 1900. It is used as a photosensitizer in photodynamic therapy. Acetylation of hematoporphyrin followed by hydrolysis of the product of that reaction affords a mixture called hematoporphyrin derivative (HPD), which is also used in photodynamic therapy. Hematoporphyrin has also been used as an antidepressant and antipsychotic since the 1920s.
雷公藤内酯(英語:Triptolide)是一个二萜类环氧化物,它由雷公藤(学名:Tripterygium wilfordii)产生。 它在体外实验和体内实验中对小鼠模型的多囊肾病和胰腺癌具有抗癌作用,但是其物理性质和严重的毒性限制了它的治疗潜力。
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Methanediamine is an aminal, a one-carbon compound and an alkane-alpha,omega-diamine.
甲萘威,也译为加保利(英語:Carbaryl,化学名:1-萘基-N-甲基氨基甲酸酯,1-Naphthyl-N-Methylcarbamate,化学式C12H11NO2),是一种氨基甲酸酯类的杀虫剂,常温常压下为无色固体,由美國聯合碳化物公司在1958年开发,2002年被拜耳公司收购,商品名:Sevin。
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Trans-4-hydroxy-L-proline is an optically active form of 4-hydroxyproline having L-trans-configuration. It has a role as a human metabolite, a plant metabolite and a mouse metabolite. It is a tautomer of a trans-4-hydroxy-L-proline zwitterion.
三氟乙酰氯,又称TFAC是一种气体,化学式 C2ClF3O。它通常以高压液体货运,有毒。
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Moxifloxacin is a natural product found in Aspergillus austroafricanus with data available.
孕二醇或孕烷二醇(英語:Pregnanediol)或称为5β-孕烷-3α,20α-二醇(5β-pregnane-3α,20α-diol)是一种孕酮在体内的无活性的代谢产物。测试尿液中孕二醇的含量可以作为测量体内孕酮水平的一种间接方法。
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Dibromomethane is a member of the class of bromomethanes that is methane substituted by two bromo groups. It is produced by marine algae. It has a role as a marine metabolite and an algal metabolite. It is a member of bromomethanes and a bromohydrocarbon.
塞来昔布(英語:celecoxib),商品名希樂葆或西乐葆,是一种选择性COX-2抑制剂,属磺酰胺非類固醇消炎止痛藥(NSAID)类, 用于治疗骨关节炎、类风湿性关节炎、急性疼痛、痛经,以及减少家族性腺瘤性息肉病患者的结肠和直肠息肉数量。
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Amphetamine (contracted from alpha-methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine. Amphetamine was discovered as a chemical in 1887 by Lazăr Edeleanu, and then as a drug in the late 1920s. It exists as two enantiomers: levoamphetamine and dextroamphetamine. Amphetamine properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers in their pure amine forms. The term is frequently used informally to refer to any combination of the enantiomers, or to either of them alone. Historically, it has been used to treat nasal congestion and depression. Amphetamine is also used as an athletic performance enhancer and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. It is a prescription drug in many countries, and unauthorized possession and distribution of amphetamine are often tightly controlled due to the significant health risks associated with recreational use. The first amphetamine pharmaceutical was Benzedrine, a brand which was used to treat a variety of conditions. Currently, pharmaceutical amphetamine is prescribed as racemic amphetamine, Adderall, dextroamphetamine, or the inactive prodrug lisdexamfetamine. Amphetamine increases monoamine and excitatory neurotransmission in the brain, with its most pronounced effects targeting the norepinephrine and dopamine neurotransmitter systems. At therapeutic doses, amphetamine causes emotional and cognitive effects such as euphoria, change in desire for sex, increased wakefulness, and improved cognitive control. It induces physical effects such as improved reaction time, fatigue resistance, decreased appetite, elevated heart rate, and increased muscle strength. Larger doses of amphetamine may impair cognitive function and induce rapid muscle breakdown. Addiction is a serious risk with heavy recreational amphetamine use, but is unlikely to occur from long-term medical use at therapeutic doses. Very high doses can result in psychosis (e.g., hallucinations, delusions and paranoia) which rarely occurs at therapeutic doses even during long-term use. Recreational doses are generally much larger than prescribed therapeutic doses and carry a far greater risk of serious side effects. Amphetamine belongs to the phenethylamine class. It is also the parent compound of its own structural class, the substituted amphetamines, which includes prominent substances such as bupropion, cathinone, MDMA, and methamphetamine. As a member of the phenethylamine class, amphetamine is also chemically related to the naturally occurring trace amine neuromodulators, specifically phenethylamine and N-methylphenethylamine, both of which are produced within the human body. Phenethylamine is the parent compound of amphetamine, while N-methylphenethylamine is a positional isomer of amphetamine that differs only in the placement of the methyl group.
氧氟沙星(英語:ofloxacin)也称氟嗪酸,商品名常为泰利必妥(Tarivid),是一种人工合成、广谱抗菌的第三代喹诺酮类(氟喹诺酮)抗菌活性的抗生素。 氧氟沙星合成于1982年,口服易吸收,快而完全,血药浓度高而持久,药物体内分布广。
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Diphenylamine is an aromatic amine containing two phenyl substituents. It has been used as a fungicide for the treatment of superficial scald in apples and pears, but is no longer approved for this purpose within the European Union. It has a role as a carotogenesis inhibitor, an antioxidant, an EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor, an antifungal agrochemical, a ferroptosis inhibitor and a radical scavenger. It is an aromatic amine, a secondary amino compound and a bridged diphenyl fungicide.
三乙酸甘油酯,结构式[CH3C(O)OCH2]2CHO(O)CCH3。
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Rhodamine B is an organic chloride salt having N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene]-N-ethylethanaminium as the counterion. An amphoteric dye commonly used as a fluorochrome. It has a role as a fluorochrome, a fluorescent probe and a histological dye. It is an organic chloride salt and a xanthene dye. It contains a rhodamine B(1+).
乙腈(jīng)(英語:acetonitrile,ACN)又稱甲基氰(methyl cyanide,MeCN)、氰甲烷(ethanenitrile),化学式CH3CN,是無色的液體,是最簡單的有機腈,並廣泛用作极性非质子溶劑。乙腈在某些条件下,也可以发生碳-碳键断裂。
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Benzene is an organic chemical compound with the molecular formula C6H6. The benzene molecule is composed of six carbon atoms joined in a planar hexagonal ring with one hydrogen atom attached to each. Because it contains only carbon and hydrogen atoms, benzene is classed as a hydrocarbon. Benzene is a natural constituent of petroleum and is one of the elementary petrochemicals. Due to the cyclic continuous pi bonds between the carbon atoms, benzene is classed as an aromatic hydrocarbon. Benzene is a colorless and highly flammable liquid with a sweet smell, and is partially responsible for the aroma of gasoline. It is used primarily as a precursor to the manufacture of chemicals with more complex structures, such as ethylbenzene and cumene, of which billions of kilograms are produced annually. Although benzene is a major industrial chemical, it finds limited use in consumer items because of its toxicity. Benzene is a volatile organic compound. Benzene is classified as a carcinogen. Its particular effects on human health, such as the long-term results of accidental exposure, have been reported on by news organizations such as The New York Times. For instance, a 2022 article stated that benzene contamination in the Boston metropolitan area caused hazardous conditions in multiple places, with the publication noting that the compound may eventually cause leukemia in some individuals.
1,12-十二烷二酸是含有十二个碳原子的二羧酸,结构式HOOC(CH2)10COOH。
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Rolipram is a member of the lclass of pyrrolidin-2-ones that is pyrrolidin-2-one bearing a 3-(cyclopentyloxy)-4-methoxyphenyl substituent at the 4-position. It is a type IV-specific phosphodiesterase (PDE4) inhibitor. It has a role as an antidepressant and an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor.
高泛酸(英語:homopantothenic acid 或 Hopantenic acid)是一种有机化合物,分子式C10H19NO5,可看做泛解酸(2,4-二羟基-3,3-二甲基丁酸)与γ-氨基丁酸(GABA)形成的酰胺,比泛解酸与β-丙氨酸形成的泛酸多一个亚甲基,因而得名。
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Picilorex (INN; brand name Roxenan; IUPAC: 3-(4-Chlorophenyl)-5-cyclopropyl-2-methylpyrrolidine) is an anorectic which is no longer marketed. It is a monoamine reuptake inhibitor, a stimulant as well as a derivate of pyrrolidine.
甲苯(英語:Toluene)是一种无色带特殊芳香味的易挥发液体,分子式為C7H8,難溶於水。甲苯是芳香族碳氫化合物的一员,它的很多性质与苯很相像,在现今实际应用中常常替代有相当毒性的苯作为有机溶剂使用,还是一种常用的化工原料,可用于制造噴漆、炸药、农药、苯甲酸、染料、合成树脂及涤纶等。同时它也是汽油的组分之一。
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Indole-3-acetic acid is a natural product found in Humulus lupulus, Balansia epichloe, and other organisms with data available.
吲哚-3-乙酸(英語:indole-3-acetic acid),简称吲哚乙酸(英語:indoleacetic acid),又稱萮乙酸,缩写为IAA,是一种杂环化合物。它属于一类重要的植物激素——生长素。这种无色的固体很可能是最重要的植物生长素。它是吲哚的衍生物,是在吲哚环上加上羧甲基后得到的物质。
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1,4-Benzoquinone is a natural product found in Blaps lethifera, Uloma tenebrionoides, and other organisms with data available.
磁麻苷(英語:Cymarin或英語:cymarine)是一种强心苷,来源于罗布麻属的罗布麻(学名:Apocynum venetum)、印第安麻(学名:Apocynum cannabinum)等物种,用于治疗心律失常。
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Salicin is an aryl beta-D-glucoside that is salicyl alcohol in which the phenolic hydrogen has been replaced by a beta-D-glucosyl residue. It has a role as a prodrug, an antipyretic, a non-narcotic analgesic, a non-steroidal anti-inflammatory drug, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor and a metabolite. It is an aryl beta-D-glucoside, an aromatic primary alcohol and a member of benzyl alcohols. It is functionally related to a salicyl alcohol.
激动素(Kinetin)是促细胞分裂的植物激素细胞分裂素的一种。激动素最初是由卡洛斯·米勒以及福克·K.·斯库格等从经过高压蒸汽处理的鲱鱼精细胞DNA中分离得到的有增强细胞分裂活性的物质。因为能诱导细胞分裂,这种物质被称为激动素。激动素能诱导相应的细胞产生生长素。在植物组织培养中,激动素通常用来诱导癒傷組織的形成(配合生长素),以及诱导癒傷組織形成芽(需要同时使用低浓度的生长素)。
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Methotrexate is a member of pteridines, a monocarboxylic acid amide and a dicarboxylic acid. It has a role as an antineoplastic agent, an antirheumatic drug, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, a DNA synthesis inhibitor, an abortifacient, a dermatologic drug, an antimetabolite and an immunosuppressive agent. It is functionally related to a L-glutamic acid. It is a conjugate acid of a methotrexate(1-).
苯乙烯也被称为乙烯基苯,是用苯取代乙烯的一个氢原子形成的有机化合物。室温下,苯乙烯是一种具有甜味的粘稠易挥发液体,但苯乙烯浓度过高时,气味就会变得令人不愉快。苯乙烯中,乙烯基的电子与苯环共轭。苯乙烯不溶于水,溶于乙醇、乙醚中,暴露于空气中逐渐发生聚合及氧化。工业上是合成树脂、离子交换树脂及合成橡胶等的重要单体。2010年,全球苯乙烯生产量約2500萬噸。
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Glycylglycine is the dipeptide of glycine, making it the simplest peptide. The compound was first synthesized by Emil Fischer and Ernest Fourneau in 1901 by boiling 2,5-diketopiperazine (glycine anhydride) with hydrochloric acid. Shaking with alkali and other synthesis methods have been reported. Because of its low toxicity, it is useful as a buffer for biological systems with effective ranges between pH 2.5–3.8 and 7.5–8.9; however, it is only moderately stable for storage once dissolved. It is used in the synthesis of more complex peptides. Glycylglycine has also been reported to be helpful in solubilizing recombinant proteins in E. coli. Using different concentrations of the glycylglycine improvement in protein solubility after cell lysis has been observed.
β-酮戊酸(英語:beta-ketopentanoate或称为3-氧代戊酸 ,英語:3-Oxopentanoic acid)是一种五碳酮体,在人体代谢中由肝脏中的奇数碳脂肪酸组成,并能迅速进入大脑。
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Toluene is a natural product found in Basella alba, Zingiber mioga, and other organisms with data available.
磺胺二甲氧嘧啶是一种磺胺类药物,其INN名称是“Sulfadimethoxine”。该药物可用于治疗呼吸道、泌尿道等部的细菌感染等病症。该药物在血液中的半衰期暂时未知,在大鼠体内的LD50(半致死量)为1.7027mol/kg。该药物目前主要用作兽药。
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Syringic acid is a dimethoxybenzene that is 3,5-dimethyl ether derivative of gallic acid. It has a role as a plant metabolite. It is a member of benzoic acids, a dimethoxybenzene and a member of phenols. It is functionally related to a gallic acid. It is a conjugate acid of a syringate.
氨三乙酸(NTA)是一種氨基多羧酸,示性式为N(CH2CO2H)3。它在常溫常壓下是一种无色固体,可做為螯合剂與Ca2+(鈣離子)、Co2+(亞鈷離子)、Cu2+(銅離子)和Fe3+(鐵離子)等金属离子形成配位化合物(螯合物)。
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Sakuranetin is a flavonoid phytoalexin that is (S)-naringenin in which the hydroxy group at position 7 is replaced by a methoxy group. It has a role as an antimycobacterial drug and a plant metabolite. It is a dihydroxyflavanone, a monomethoxyflavanone, a flavonoid phytoalexin, a member of 4'-hydroxyflavanones and a (2S)-flavan-4-one. It is functionally related to a (S)-naringenin.
色醇(英語:Tryptophol)是一種芳香醇,可誘導人類睡眠。它作為酒精發酵的副產品存在於葡萄酒中。它於1912年由費利克斯·埃爾利希首次描述。它也由昏睡病中的錐蟲寄生蟲產生。 它作為二硫龍治療的副作用在肝臟中形成。
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Glutathione is a tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine. It has a role as a skin lightening agent, a human metabolite, an Escherichia coli metabolite, a mouse metabolite, a geroprotector, an antioxidant and a cofactor. It is a tripeptide, a thiol and a L-cysteine derivative. It is a conjugate acid of a glutathionate(1-).
异烟酸(吡啶-4-甲酸)是一种有机化合物,化学式为C5H4N(CO2H),是吡啶甲酸的同分异构体之一。它可由吡啶-4-甲醛、吡啶-4-甲醇或4-甲基吡啶的氧化反应制得。它和氯化亚砜反应,可以得到吡啶-4-甲酰氯。
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Succinimide is an organic compound with the formula (CH2)2(CO)2NH. This white solid is used in a variety of organic syntheses, as well as in some industrial silver plating processes. The compound is classified as a cyclic imide. It may be prepared by thermal decomposition of ammonium succinate.
五氯苯(英語:Pentachlorobenzene,缩写PeCB)是一种有机氯芳香族化合物,分子式C6HCl5,其中苯环上的五个氢原子被氯原子取代。五氯苯曾在工业上有多种用途,但由于其是一种持久性有機污染物(POP),在2009年的斯德哥爾摩公約中被禁止使用。
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16-Methoxytabersonine is a natural product found in Alstonia yunnanensis, Melodinus fusiformis, and other organisms with data available.
16-甲氧基水甘草碱(英語:16-Methoxytabersonine)是一种有机化合物,分子式C22H26N2O3,属于单萜类吲哚生物碱,存在于長春花(Catharanthus roseus)等植物中。
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Diclofenac, sold under the brand name Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. It can be taken orally (swallowed by mouth), inserted rectally as a suppository, injected intramuscularly, injected intravenously, applied to the skin topically, or through eye drops. Improvements in pain last up to eight hours. It is also available as the fixed-dose combination diclofenac/misoprostol (Arthrotec) to help protect the stomach. Common side effects include abdominal pain, gastrointestinal bleeding, nausea, dizziness, headache, and swelling. Serious side effects may include heart disease, stroke, kidney problems, and stomach ulceration. Use is not recommended in the third trimester of pregnancy. It is likely safe during breastfeeding. Diclofenac is believed to work by decreasing the production of prostaglandins, like other drugs in this class. In 2022, it was the 51st most commonly prescribed medication in the United States, with more than 12 million prescriptions. It is available as its acid or in two salts, as either diclofenac sodium or potassium.
十七烷是一種有機化合物,一種化學式為C17H36的烷烴。十七烷有24894個同分異構體。 有最多支链的十七烷是四叔丁基甲烷,不过由于空间位阻,它被认为不存在。实际上,据信它是最小的不可能被合成的烷烃。
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Dansyl chloride or 5-(dimethylamino)naphthalene-1-sulfonyl chloride is a reagent that reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-green–fluorescent sulfonamide adducts. It can also be made to react with secondary amines. Dansyl chloride is widely used to modify amino acids; specifically, protein sequencing and amino acid analysis. Dansyl chloride may also be denoted DNSC. Likewise, a similar derivative, dansyl amide is known as DNSA. In addition, these protein-DNSC conjugates are sensitive to their immediate environment. This, in combination with their ability to accept energy (as in fluorescence resonance energy transfer) from the amino acid tryptophan, allows this labeling technique to be used in investigating protein folding and dynamics. The fluorescence of these sulfonamide adducts can be enhanced by adding alpha-cyclodextrin. Dansyl chloride is unstable in dimethyl sulfoxide, which should never be used to prepare solutions of the reagent. The extinction coefficient of dansyl derivatives are important for measuring their concentration in solution. Dansyl chloride is one of the simplest sulfonamide derivatives, so it commonly serves as a starting reagent for the production of other derivatives. Exotic derivatives may have very different extinction coefficients, but others, such as dansyl amide, are similar to dansyl chloride in absorption and fluorescence characteristics. But even for dansyl chloride, there are a variety of extinction coefficient values that have been reported. Some of the values are used to estimate the extent of success in attempts to conjugate the dye to a protein. Other values may be used to determine a precise concentration of a stock solution. See the table below for specific values and their uses. For all of the studies below, the absorption value is always taken at the maximum that appears between 310 nm and 350 nm. The peak is broad, so the measurement is not very sensitive to wavelength miscalibration of the spectrophotometer, and error due to miscalibration can be avoided by taking the value at the maximum instead of strictly using 330 nm.
二甲基三硫(缩写:DMTS)是一种有机化合物,化学式为CH3S3CH3,它是最简单的有机三硫化物。它是具有恶臭气味的可燃液体,其含量在万亿分之一时便可以被检测到。
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Cimetidine is a member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach. It has a role as a H2-receptor antagonist, a P450 inhibitor, an anti-ulcer drug, an analgesic and an adjuvant. It is a member of guanidines, a member of imidazoles, an aliphatic sulfide and a nitrile.
半乳糖醇(英語:Galactitol 或 dulcitol)是一种糖醇,是半乳糖的还原产物。在半乳糖激酶缺乏症(一种半乳糖血症)患者中,多余的半乳糖醇会在晶状体积累而导致白内障。
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Bromoethane, also known as ethyl bromide, is a chemical compound of the haloalkanes group. It is abbreviated by chemists as EtBr (which is also used as an abbreviation for ethidium bromide). This volatile compound has an ether-like odor.
多索茶碱(英語:Doxofylline,或 doxophylline)是一种有机化合物,化学式C11H14N4O4,具有磷酸二酯酶抑制剂作用,可用作支气管扩张药。
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Sucrose is a natural product found in Quercus castaneifolia, Ceiba speciosa, and other organisms with data available.
麴酸(C6H6O4;學名5-羥基-2-(羥甲基)-4-吡喃酮),亦作曲酸或鞠酸,是一種化學螯劑,有多種真菌會分泌,特別是米麴菌(Aspergillus oryzae)。
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