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BrainLM model

The pretrained model of Brain Language Model (BrainLM) aims to achieve a general understanding of brain dynamics through self-supervised masked prediction. It is introduced in this paper and its code is available at this repository

Model Details

Model Description

We introduce the Brain Language Model (BrainLM), a foundation model for brain activity dynamics trained on 6,700 hours of fMRI recordings. Utilizing self-supervised masked-prediction training, BrainLM demonstrates proficiency in both fine-tuning and zero-shot inference tasks. Fine-tuning allows for the prediction of clinical variables and future brain states. In zero-shot inference, the model identifies functional networks and generates interpretable latent representations of neural activity. Furthermore, we introduce a novel prompting technique, allowing BrainLM to function as an in silico simulator of brain activity responses to perturbations. BrainLM offers a novel framework for the analysis and understanding of large-scale brain activity data, serving as a “lens” through which new data can be more effectively interpreted.

  • Developed by: van Dijk Lab at Yale University
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  • Model type: [More Information Needed]
  • Language(s) (NLP): [More Information Needed]
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  • Finetuned from model [optional]: [More Information Needed]

Model Sources [optional]

Uses

Direct Use

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Downstream Use [optional]

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Out-of-Scope Use

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Bias, Risks, and Limitations

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Recommendations

Users (both direct and downstream) should be made aware of the risks, biases and limitations of the model. More information needed for further recommendations.

How to Get Started with the Model

Use the code below to get started with the model.

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Training Details

Training Data

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Training Procedure

Preprocessing [optional]

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Training Hyperparameters

  • Training regime: [More Information Needed]

Speeds, Sizes, Times [optional]

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Evaluation

Testing Data, Factors & Metrics

Testing Data

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Factors

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Metrics

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Results

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Summary

Model Examination [optional]

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Environmental Impact

Carbon emissions can be estimated using the Machine Learning Impact calculator presented in Lacoste et al. (2019).

  • Hardware Type: [More Information Needed]
  • Hours used: [More Information Needed]
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Technical Specifications [optional]

Model Architecture and Objective

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Compute Infrastructure

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Hardware

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Software

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Citation [optional]

BibTeX:

 @article{ortega2023brainlm,
  title={BrainLM: A foundation model for brain activity recordings},
  author={Ortega Caro, Josue and Oliveira Fonseca, Antonio Henrique and Averill, Christopher and Rizvi, Syed A and Rosati, Matteo and Cross, James L and Mittal, Prateek and Zappala, Emanuele and Levine, Daniel and Dhodapkar, Rahul M and others},
  journal={bioRxiv},
  pages={2023--09},
  year={2023},
  publisher={Cold Spring Harbor Laboratory}
}

APA:

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Glossary [optional]

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Model Card Authors [optional]

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Model Card Contact

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