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# EyeNED OCT-ONH: vendor-neutral analysis of optic nerve head OCT
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
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This repository provides a vendor-neutral assessment of the anatomy of the optic nerve head, including the extraction of common features related to optic neuropathy, such as cpRNFL thickness and BMO-MRW. This method contains two steps:
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1. A CNN-based segmentation of the ONH anatomy -- which was implemented in [nnUNetv2](https://github.com/MIC-DKFZ/nnUNet/).
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2. Comprehensive feature extraction, for both 3D cube or raster acquisitions and circular/radial scan patterns
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
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The model was trained on the following devices and acquisition modes:
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- Zeiss Cirrus HD-OCT 5000 -- 6x6mm cube (200x200)
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- Heidelberg Spectralis -- circular and radial scans
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- Topcon 3D OCT 2000 -- 6x6mm raster (128x512)
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## Using our model
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This repository contains the model weights and metadata. We used [nnunetv2](https://github.com/MIC-DKFZ/nnUNet) to train the model, so look into that repository to learn more about its implementation and usage.
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If you use this model for your research, please cite our manuscript:
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S.J. Driessen et al. CNN-based device-agnostic feature extraction from ONH OCT scans, Translational Vision Science & Technology (Accepted, 2024) -- details will be added upon publication
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Please feel free to post an issue if you run into them. Are you interested in the details or do you want to collaborate further? Please contact k.vangarderen \[at\] erasmusmc.nl
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## Copyright notice
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EyeNED OCT-ONH segmentation and feature extraction
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Copyright (C) 2024 Erasmus MC
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This program is free software: you can redistribute it and/or modify
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it under the terms of the GNU Affero General Public License as published
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by the Free Software Foundation, either version 3 of the License, or
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(at your option) any later version.
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This program is distributed in the hope that it will be useful,
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but WITHOUT ANY WARRANTY; without even the implied warranty of
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MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
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GNU Affero General Public License for more details.
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You should have received a copy of the GNU Affero General Public License
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along with this program. If not, see <https://www.gnu.org/licenses/>. |