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       <a href="genomics.html">DRC OMICS</a>
       <a href="pharmaco.html">DRC Pharmacometrics</a>
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         <h2>Computational Biology</h2>
+        <p><img src="https://th.bing.com/th/id/OIG.tUfnEp4OWoDONNSs4Z7w?w=270&h=270&c=6&r=0&o=5&pid=ImgGn" height="220px" width="220px">
+          Computational biology is an interdisciplinary field that applies mathematical and computational methods to analyze biological data. Computational biology 
+          aims to understand the structure, function, evolution and interaction of biological systems at different levels of organization, from molecules to ecosystems.
+           Computational biology can also help to design and test new hypotheses, experiments and therapies in biotechnology and medicine. 
+           Some of the main topics of computational biology include bioinformatics, genomics, proteomics, metabolomics, systems biology, phylogenetics, 
+           structural biology and synthetic biology.</p>
+           <p>Bioinformatics is the application of computational methods to analyze biological data. It involves the use of algorithms, databases, 
+            software tools and statistical techniques to process, store and interpret information from various sources such as DNA sequences, protein 
+            structures, gene expression and metabolic pathways. 
+            Bioinformatics can help answer questions such as how genes function, how diseases develop and how organisms evolve.</p>
+            <p>Genomics is the study of the structure, function, and evolution of genomes, which are the complete sets of genetic information in an organism. 
+              Genomics can help us understand the molecular basis of life, disease, and diversity. Genomics can also enable the development of new technologies 
+              and applications in fields such as medicine, agriculture, biotechnology, and environmental science.</p>
+
+            <p>Proteomics is a field of science that studies the structure, function, and interactions of proteins in living organisms. Proteins are essential 
+              for many biological processes, such as metabolism, signaling, immunity, and gene expression. Proteomics uses various techniques, such as mass spectrometry,
+               protein purification, and bioinformatics, to identify and quantify proteins and their modifications. Proteomics can provide insights into the molecular
+                mechanisms of diseases, drug targets, biomarkers, and cellular pathways.
+            </p>
+          <p>Metabolomics is the study of the chemical processes that occur in living organisms, such as the production and degradation of metabolites. Metabolomics can 
+            provide insights into the metabolic state, function, and regulation of cells, tissues, and organs. 
+            Metabolomics can also be used to identify biomarkers, discover new pathways, and understand disease mechanisms.</p>
+
+            <p>Phylogenetics is the study of the evolutionary history and relationships among different groups of organisms. It uses various methods, such 
+              as molecular sequences, morphological traits, and fossils, to infer the patterns of descent and divergence among taxa. Phylogenetic trees are 
+              graphical representations of these relationships, showing the branching order and relative time of speciation events. Phylogenetics has many 
+              applications in biology, such as understanding the origin and diversity of life, 
+              reconstructing the ancestral features of organisms, and testing hypotheses about adaptation and coevolution.</p>
+              <h2>Transcriptomics</h2>
+              <p>Transcriptomics is the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of an organism or a cell. 
+                Transcriptomics can reveal the expression levels of genes and their regulation under different conditions, such as development, stress, disease, or treatment. 
+                Transcriptomics can also identify novel transcripts, such as non-coding RNAs, alternative splicing variants, and fusion genes. 
+                Transcriptomics relies on high-throughput sequencing technologies, such as RNA-seq, to capture and analyze the transcriptome data.</p>
+              <h2>Spatial Transcriptomics</h2>
+              <p>Park HE, Jo SH, Lee RH, Macks CP, Ku T, Park J, Lee CW, Hur JK, Sohn CH. Spatial Transcriptomics: Technical Aspects of Recent Developments and 
+                Their Applications in Neuroscience and Cancer Research. Adv Sci (Weinh). 2023 Apr 7:e2206939. doi: 10.1002/advs.202206939. Epub ahead of print.
+                 PMID: 37026425.</p>
+              
+              <p><img src="https://onlinelibrary.wiley.com/cms/asset/e7d09386-ea3e-4465-a6ea-a3a255a41caa/advs5479-fig-0001-m.jpg" width="900 px" height="800px"></p>
+              <p>Spatial transcriptomics is a newly emerging field that enables high-throughput investigation of the spatial localization of transcripts and related 
+                analyses in various applications for biological systems. By transitioning from conventional biological studies to “in situ” biology, spatial 
+                transcriptomics can provide transcriptome-scale spatial information. Currently, the ability to simultaneously characterize gene expression profiles
+                 of cells and relevant cellular environment is a paradigm shift for biological studies. In this review, recent progress in spatial transcriptomics and 
+                 its applications in neuroscience and cancer studies are highlighted. Technical aspects of existing technologies and future directions of new 
+                 developments (as of March 2023), computational analysis of spatial transcriptome data, application notes in neuroscience and cancer studies, and 
+                 discussions regarding future directions of spatial multi-omics and their expanding roles in biomedical applications are emphasized.</p>
+      </div>
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       <div class="nav_tech">
         <a href="https://medium.com/paper-club/understanding-pyros-model-and-guide-a-love-story-7f3aa0603886" target="_blank">Pyro Model and Guide</a>
         <a href="https://mc-stan.org/" target="_blank">Stan</a>
@@ -31,12 +77,13 @@
         <a href="https://openai.com/blog/chatgpt" target="_blank">ChatGPT</a>
         <a href="https://arxiv.org/" target="_blank">ArXiv</a>
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-          Copyright &#169; Dulun Research & Consulting<br>
-          Last updated on April 13 2023<br>
-          <a href="mailto:compute@dulun.com" target="_blank">Contact us</a><br>
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+      <br>
+      Copyright &#169; Dulun Research & Consulting<br>
+      Last updated on April 11th 2023<br>
+      <a href="mailto:compute@dulun.com" target="_blank">Contact us</a><br>
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