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| { | |
| "biomarkers": { | |
| "Glucose": { | |
| "unit": "mg/dL", | |
| "normal_range": {"min": 70, "max": 100}, | |
| "critical_low": 54, | |
| "critical_high": 400, | |
| "type": "fasting", | |
| "gender_specific": false, | |
| "description": "Fasting blood glucose level", | |
| "clinical_significance": { | |
| "low": "Hypoglycemia - risk of confusion, seizures", | |
| "high": "Hyperglycemia - diabetes risk, requires further testing" | |
| } | |
| }, | |
| "Cholesterol": { | |
| "unit": "mg/dL", | |
| "normal_range": {"min": 125, "max": 200}, | |
| "critical_low": 100, | |
| "critical_high": 240, | |
| "type": "total", | |
| "gender_specific": false, | |
| "description": "Total cholesterol level", | |
| "clinical_significance": { | |
| "low": "Malnutrition, liver disease, or hyperthyroidism", | |
| "high": "Increased cardiovascular disease risk" | |
| } | |
| }, | |
| "Hemoglobin": { | |
| "unit": "g/dL", | |
| "normal_range": { | |
| "male": {"min": 13.5, "max": 17.5}, | |
| "female": {"min": 12.0, "max": 15.5} | |
| }, | |
| "critical_low": 7, | |
| "critical_high": 18, | |
| "gender_specific": true, | |
| "description": "Oxygen-carrying protein in red blood cells", | |
| "clinical_significance": { | |
| "low": "Anemia - fatigue, weakness, organ hypoxia", | |
| "high": "Polycythemia - increased blood viscosity, clotting risk" | |
| } | |
| }, | |
| "Platelets": { | |
| "unit": "cells/μL", | |
| "normal_range": {"min": 150000, "max": 400000}, | |
| "critical_low": 50000, | |
| "critical_high": 1000000, | |
| "gender_specific": false, | |
| "description": "Blood clotting cells", | |
| "clinical_significance": { | |
| "low": "Thrombocytopenia - bleeding risk", | |
| "high": "Thrombocytosis - clotting risk" | |
| } | |
| }, | |
| "White Blood Cells": { | |
| "unit": "cells/μL", | |
| "normal_range": {"min": 4000, "max": 11000}, | |
| "critical_low": 2000, | |
| "critical_high": 30000, | |
| "gender_specific": false, | |
| "description": "Immune system cells", | |
| "clinical_significance": { | |
| "low": "Leukopenia - infection risk", | |
| "high": "Leukocytosis - infection or leukemia" | |
| } | |
| }, | |
| "Red Blood Cells": { | |
| "unit": "million/μL", | |
| "normal_range": { | |
| "male": {"min": 4.5, "max": 5.9}, | |
| "female": {"min": 4.0, "max": 5.2} | |
| }, | |
| "critical_low": 3.0, | |
| "critical_high": null, | |
| "gender_specific": true, | |
| "description": "Oxygen-carrying blood cells", | |
| "clinical_significance": { | |
| "low": "Severe anemia - organ damage risk" | |
| } | |
| }, | |
| "Hematocrit": { | |
| "unit": "%", | |
| "normal_range": { | |
| "male": {"min": 38.8, "max": 50.0}, | |
| "female": {"min": 34.9, "max": 44.5} | |
| }, | |
| "critical_low": 25, | |
| "critical_high": 60, | |
| "gender_specific": true, | |
| "description": "Percentage of blood volume occupied by red blood cells", | |
| "clinical_significance": { | |
| "low": "Severe anemia", | |
| "high": "Polycythemia - stroke risk" | |
| } | |
| }, | |
| "Mean Corpuscular Volume": { | |
| "unit": "fL", | |
| "normal_range": {"min": 80, "max": 100}, | |
| "critical_low": null, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "Average red blood cell size", | |
| "clinical_significance": { | |
| "low": "Microcytic anemia (iron deficiency, thalassemia)", | |
| "high": "Macrocytic anemia (B12/folate deficiency)" | |
| } | |
| }, | |
| "Mean Corpuscular Hemoglobin": { | |
| "unit": "pg", | |
| "normal_range": {"min": 27, "max": 33}, | |
| "critical_low": null, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "Average hemoglobin per red blood cell", | |
| "clinical_significance": { | |
| "low": "Hypochromic anemia" | |
| } | |
| }, | |
| "Mean Corpuscular Hemoglobin Concentration": { | |
| "unit": "g/dL", | |
| "normal_range": {"min": 32, "max": 36}, | |
| "critical_low": null, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "Average hemoglobin concentration in red blood cells", | |
| "clinical_significance": { | |
| "low": "Hypochromic anemia" | |
| } | |
| }, | |
| "Insulin": { | |
| "unit": "μIU/mL", | |
| "normal_range": {"min": 2.6, "max": 24.9}, | |
| "critical_low": null, | |
| "critical_high": 25, | |
| "type": "fasting", | |
| "gender_specific": false, | |
| "description": "Fasting insulin level", | |
| "clinical_significance": { | |
| "high": "Insulin resistance - diabetes/metabolic syndrome risk" | |
| } | |
| }, | |
| "BMI": { | |
| "unit": "kg/m²", | |
| "normal_range": {"min": 18.5, "max": 24.9}, | |
| "critical_low": 15, | |
| "critical_high": 50, | |
| "gender_specific": false, | |
| "description": "Body Mass Index", | |
| "clinical_significance": { | |
| "low": "Underweight - malnutrition risk", | |
| "high": "Obese - cardiovascular and metabolic disease risk" | |
| } | |
| }, | |
| "Systolic Blood Pressure": { | |
| "unit": "mmHg", | |
| "normal_range": {"min": 90, "max": 120}, | |
| "critical_low": 70, | |
| "critical_high": 180, | |
| "gender_specific": false, | |
| "description": "Blood pressure during heart contraction", | |
| "clinical_significance": { | |
| "low": "Hypotension - dizziness, fainting", | |
| "high": "Hypertension - cardiovascular disease risk" | |
| } | |
| }, | |
| "Diastolic Blood Pressure": { | |
| "unit": "mmHg", | |
| "normal_range": {"min": 60, "max": 80}, | |
| "critical_low": 40, | |
| "critical_high": 120, | |
| "gender_specific": false, | |
| "description": "Blood pressure during heart relaxation", | |
| "clinical_significance": { | |
| "low": "Hypotension", | |
| "high": "Hypertension" | |
| } | |
| }, | |
| "Triglycerides": { | |
| "unit": "mg/dL", | |
| "normal_range": {"min": 40, "max": 150}, | |
| "critical_low": null, | |
| "critical_high": 500, | |
| "gender_specific": false, | |
| "description": "Type of blood fat", | |
| "clinical_significance": { | |
| "high": "Pancreatitis risk, cardiovascular disease" | |
| } | |
| }, | |
| "HbA1c": { | |
| "unit": "%", | |
| "normal_range": {"min": 4.0, "max": 5.7}, | |
| "critical_low": null, | |
| "critical_high": 14, | |
| "gender_specific": false, | |
| "description": "3-month average blood glucose", | |
| "clinical_significance": { | |
| "high": "Diabetes (≥6.5%), Prediabetes (5.7-6.4%)" | |
| } | |
| }, | |
| "LDL Cholesterol": { | |
| "unit": "mg/dL", | |
| "normal_range": {"min": 40, "max": 100}, | |
| "critical_low": null, | |
| "critical_high": 190, | |
| "gender_specific": false, | |
| "description": "Low-density lipoprotein (bad cholesterol)", | |
| "clinical_significance": { | |
| "high": "Atherosclerosis, heart disease risk" | |
| } | |
| }, | |
| "HDL Cholesterol": { | |
| "unit": "mg/dL", | |
| "normal_range": { | |
| "male": {"min": 40, "max": 100}, | |
| "female": {"min": 50, "max": 100} | |
| }, | |
| "critical_low": 25, | |
| "critical_high": null, | |
| "gender_specific": true, | |
| "description": "High-density lipoprotein (good cholesterol)", | |
| "clinical_significance": { | |
| "low": "Cardiovascular disease risk" | |
| } | |
| }, | |
| "ALT": { | |
| "unit": "U/L", | |
| "normal_range": {"min": 7, "max": 56}, | |
| "critical_low": null, | |
| "critical_high": 200, | |
| "gender_specific": false, | |
| "description": "Alanine aminotransferase (liver enzyme)", | |
| "clinical_significance": { | |
| "high": "Liver damage or disease" | |
| } | |
| }, | |
| "AST": { | |
| "unit": "U/L", | |
| "normal_range": {"min": 10, "max": 40}, | |
| "critical_low": null, | |
| "critical_high": 200, | |
| "gender_specific": false, | |
| "description": "Aspartate aminotransferase (liver/heart enzyme)", | |
| "clinical_significance": { | |
| "high": "Liver or heart damage" | |
| } | |
| }, | |
| "Heart Rate": { | |
| "unit": "bpm", | |
| "normal_range": {"min": 60, "max": 100}, | |
| "critical_low": 50, | |
| "critical_high": 120, | |
| "gender_specific": false, | |
| "description": "Beats per minute", | |
| "clinical_significance": { | |
| "low": "Bradycardia - dizziness, fatigue", | |
| "high": "Tachycardia - palpitations, anxiety" | |
| } | |
| }, | |
| "Creatinine": { | |
| "unit": "mg/dL", | |
| "normal_range": { | |
| "male": {"min": 0.7, "max": 1.3}, | |
| "female": {"min": 0.6, "max": 1.1} | |
| }, | |
| "critical_low": null, | |
| "critical_high": 3.0, | |
| "gender_specific": true, | |
| "description": "Kidney function marker", | |
| "clinical_significance": { | |
| "high": "Kidney dysfunction or failure" | |
| } | |
| }, | |
| "Troponin": { | |
| "unit": "ng/mL", | |
| "normal_range": {"min": 0, "max": 0.04}, | |
| "critical_low": null, | |
| "critical_high": 0.4, | |
| "gender_specific": false, | |
| "description": "Cardiac muscle damage marker", | |
| "clinical_significance": { | |
| "high": "Myocardial injury or infarction (heart attack)" | |
| } | |
| }, | |
| "C-reactive Protein": { | |
| "unit": "mg/L", | |
| "normal_range": {"min": 0, "max": 3.0}, | |
| "critical_low": null, | |
| "critical_high": 10, | |
| "gender_specific": false, | |
| "description": "Inflammation marker", | |
| "clinical_significance": { | |
| "high": "Acute inflammation or infection" | |
| } | |
| }, | |
| "Urea": { | |
| "unit": "mg/dL", | |
| "normal_range": {"min": 7, "max": 20}, | |
| "critical_low": null, | |
| "critical_high": 50, | |
| "gender_specific": false, | |
| "description": "Blood urea nitrogen (kidney function marker)", | |
| "clinical_significance": { | |
| "high": "Kidney dysfunction, dehydration, or high-protein diet", | |
| "low": "Liver disease or malnutrition" | |
| } | |
| }, | |
| "TSH": { | |
| "unit": "mIU/L", | |
| "normal_range": {"min": 0.4, "max": 4.0}, | |
| "critical_low": 0.1, | |
| "critical_high": 10, | |
| "gender_specific": false, | |
| "description": "Thyroid-stimulating hormone", | |
| "clinical_significance": { | |
| "low": "Hyperthyroidism", | |
| "high": "Hypothyroidism" | |
| } | |
| }, | |
| "T3": { | |
| "unit": "ng/dL", | |
| "normal_range": {"min": 80, "max": 200}, | |
| "critical_low": null, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "Triiodothyronine (thyroid hormone)", | |
| "clinical_significance": { | |
| "low": "Hypothyroidism", | |
| "high": "Hyperthyroidism" | |
| } | |
| }, | |
| "T4": { | |
| "unit": "μg/dL", | |
| "normal_range": {"min": 5.0, "max": 12.0}, | |
| "critical_low": null, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "Thyroxine (thyroid hormone)", | |
| "clinical_significance": { | |
| "low": "Hypothyroidism", | |
| "high": "Hyperthyroidism" | |
| } | |
| }, | |
| "Sodium": { | |
| "unit": "mEq/L", | |
| "normal_range": {"min": 136, "max": 145}, | |
| "critical_low": 120, | |
| "critical_high": 155, | |
| "gender_specific": false, | |
| "description": "Blood sodium level (electrolyte)", | |
| "clinical_significance": { | |
| "low": "Hyponatremia - confusion, seizures", | |
| "high": "Hypernatremia - dehydration, thirst" | |
| } | |
| }, | |
| "Potassium": { | |
| "unit": "mEq/L", | |
| "normal_range": {"min": 3.5, "max": 5.0}, | |
| "critical_low": 2.5, | |
| "critical_high": 6.5, | |
| "gender_specific": false, | |
| "description": "Blood potassium level (electrolyte)", | |
| "clinical_significance": { | |
| "low": "Hypokalemia - muscle weakness, arrhythmia", | |
| "high": "Hyperkalemia - cardiac arrest risk" | |
| } | |
| }, | |
| "Calcium": { | |
| "unit": "mg/dL", | |
| "normal_range": {"min": 8.5, "max": 10.5}, | |
| "critical_low": 7.0, | |
| "critical_high": 12.0, | |
| "gender_specific": false, | |
| "description": "Blood calcium level", | |
| "clinical_significance": { | |
| "low": "Hypocalcemia - muscle cramps, numbness", | |
| "high": "Hypercalcemia - kidney stones, bone pain" | |
| } | |
| }, | |
| "Chloride": { | |
| "unit": "mEq/L", | |
| "normal_range": {"min": 98, "max": 106}, | |
| "critical_low": 80, | |
| "critical_high": 120, | |
| "gender_specific": false, | |
| "description": "Blood chloride level (electrolyte)", | |
| "clinical_significance": { | |
| "low": "Metabolic alkalosis", | |
| "high": "Metabolic acidosis" | |
| } | |
| }, | |
| "Bicarbonate": { | |
| "unit": "mEq/L", | |
| "normal_range": {"min": 22, "max": 28}, | |
| "critical_low": 15, | |
| "critical_high": 35, | |
| "gender_specific": false, | |
| "description": "Blood bicarbonate (acid-base balance)", | |
| "clinical_significance": { | |
| "low": "Metabolic acidosis", | |
| "high": "Metabolic alkalosis" | |
| } | |
| }, | |
| "Uric_Acid": { | |
| "unit": "mg/dL", | |
| "normal_range": { | |
| "male": {"min": 3.4, "max": 7.0}, | |
| "female": {"min": 2.4, "max": 6.0} | |
| }, | |
| "critical_low": null, | |
| "critical_high": 10, | |
| "gender_specific": true, | |
| "description": "Blood uric acid level", | |
| "clinical_significance": { | |
| "high": "Gout risk, kidney stone risk" | |
| } | |
| }, | |
| "Total_Protein": { | |
| "unit": "g/dL", | |
| "normal_range": {"min": 6.0, "max": 8.3}, | |
| "critical_low": 4.5, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "Total serum protein", | |
| "clinical_significance": { | |
| "low": "Liver disease, malnutrition, kidney disease", | |
| "high": "Chronic inflammation, multiple myeloma" | |
| } | |
| }, | |
| "Albumin": { | |
| "unit": "g/dL", | |
| "normal_range": {"min": 3.5, "max": 5.5}, | |
| "critical_low": 2.0, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "Serum albumin (liver function)", | |
| "clinical_significance": { | |
| "low": "Liver disease, malnutrition, kidney disease" | |
| } | |
| }, | |
| "Globulin": { | |
| "unit": "g/dL", | |
| "normal_range": {"min": 2.0, "max": 3.5}, | |
| "critical_low": null, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "Serum globulin (immune proteins)", | |
| "clinical_significance": { | |
| "low": "Immune deficiency", | |
| "high": "Chronic inflammation, liver disease" | |
| } | |
| }, | |
| "AG_Ratio": { | |
| "unit": "ratio", | |
| "normal_range": {"min": 1.1, "max": 2.5}, | |
| "critical_low": null, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "Albumin/Globulin ratio", | |
| "clinical_significance": { | |
| "low": "Liver disease, autoimmune conditions", | |
| "high": "Generally not clinically significant" | |
| } | |
| }, | |
| "Bilirubin_Total": { | |
| "unit": "mg/dL", | |
| "normal_range": {"min": 0.1, "max": 1.2}, | |
| "critical_low": null, | |
| "critical_high": 5.0, | |
| "gender_specific": false, | |
| "description": "Total bilirubin (liver function marker)", | |
| "clinical_significance": { | |
| "high": "Liver disease, bile duct obstruction, hemolysis" | |
| } | |
| }, | |
| "ALP": { | |
| "unit": "U/L", | |
| "normal_range": {"min": 44, "max": 147}, | |
| "critical_low": null, | |
| "critical_high": 500, | |
| "gender_specific": false, | |
| "description": "Alkaline phosphatase (liver/bone enzyme)", | |
| "clinical_significance": { | |
| "high": "Liver disease, bone disorders, bile duct issues" | |
| } | |
| }, | |
| "BUN": { | |
| "unit": "mg/dL", | |
| "normal_range": {"min": 7, "max": 20}, | |
| "critical_low": null, | |
| "critical_high": 50, | |
| "gender_specific": false, | |
| "description": "Blood urea nitrogen (kidney function)", | |
| "clinical_significance": { | |
| "high": "Kidney dysfunction, dehydration" | |
| } | |
| }, | |
| "BUN_Creatinine_Ratio": { | |
| "unit": "ratio", | |
| "normal_range": {"min": 10, "max": 20}, | |
| "critical_low": null, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "BUN to Creatinine ratio", | |
| "clinical_significance": { | |
| "high": "Pre-renal cause (dehydration, GI bleeding)", | |
| "low": "Intrinsic renal disease, liver disease" | |
| } | |
| }, | |
| "VLDL": { | |
| "unit": "mg/dL", | |
| "normal_range": {"min": 2, "max": 30}, | |
| "critical_low": null, | |
| "critical_high": null, | |
| "gender_specific": false, | |
| "description": "Very low-density lipoprotein cholesterol", | |
| "clinical_significance": { | |
| "high": "Increased cardiovascular risk" | |
| } | |
| } | |
| } | |
| } | |