RAG Files/Alzheimer's Disease - Prevention - 2.txt

Medication
Cardiovascular risk factors, such as hypercholesterolaemia, hypertension, diabetes, and smoking, are associated with a higher risk of onset and worsened course of AD.[149][150] The use of statins to lower cholesterol may be of benefit in Alzheimer's.[151] Antihypertensive and antidiabetic medications in individuals without overt cognitive impairment may decrease the risk of dementia by influencing cerebrovascular pathology.[1][152] More research is needed to examine the relationship with Alzheimer's disease specifically; clarification of the direct role medications play versus other concurrent lifestyle changes (diet, exercise, smoking) is needed.[1]

Depression is associated with an increased risk for Alzheimer's disease; management with antidepressants may provide a preventative measure.[153]