Question: can cymbalta cause muscle jerking?
Answer: Leg Jerks, Muscle Twitches, and Rarely Seizures Seizures are listed as a rare but serious side effect of Cymbalta, occurring in roughly 3 out of every 10,500 patients. But more subtle effects, such as restless legs, muscle twitches or spasms, or leg jerks may be experienced by a larger number of people.