Question: is apixaban a direct thrombin inhibitor?
Answer: Apixaban is the third anticoagulant to be approved in the US for this indication, following the direct thrombin inhibitor dabigatran (Pradaxa, Boehringer Ingelheim) and the factor Xa inhibitor rivaroxaban (Xarelto, Bayer/Johnson & Johnson). Like rivaroxaban, apixaban is a factor Xa inhibitor.