Question: are there alligators in the pee dee river?
Answer: FLORENCE, SC (WMBF) You can find some of the biggest alligators in the US in the Pee Dee region of South Carolina. "They're in the water; the Pee Dee River is full of alligators, and Jeffries Creek that runs up through the middle of Florence has alligators in it," said Dennis Matherly.