Question: how is duquesne university pronounce?
Answer: I think the question should be, Why is “DUQUESNE” pronounced doo-KAYN. Duquesne, DuQuesne or Du Quesne (usually /duːˈkeɪn/; French: [dykɛːn]) is a family name derived from a Northern dialectal form of French du chêne ("of the oak"). In European pronunciations, the ‹s› in “Duquesne” is silent.