Question: what is the most severe consequence of a type 1 hypersensitivity reaction?
Answer: Refers to a potentially life-threatening acute reaction, classically a type I hypersensitivity, involving the sudden release of mediators from mast cells and basophils. May lead to circulatory failure (distributive shock). Anaphylactic-like symptoms may also be caused by a pseudoallergic reaction (see pseudoallergy).