Question: how much folic acid to give with methotrexate?
Answer: The most commonly recommended dose regimens are 5mg folic acid taken the day after the methotrexate dose or 1mg folic acid daily except on the day of methotrexate. The British Society for Rheumatology recommends that patients on methotrexate are co-prescribed a minimum dose of 5mg folic acid once weekly.