Question: do thiazides cause kidney stones?
Answer: In unadjusted analyses, a high vs low dose of thiazide diuretic was associated with a higher risk of a kidney stone event (HRunadj = 1.19, 95% CI: 1.01-1.41), which was attenuated after adjustment (HRadj = 1.10, 95% CI: 0.93-1.31) (Table 2).