Question: how long does it take for mesalamine suppositories to work?
Answer: DISCUSSION. Our study substantiates the clinical efficacy and safety of mesalamine 500 mg suppositories taken once a day for the treatment of ulcerative proctitis in pediatric patients age 5–17 years. Improvement of the proctitis, as measured by DAI scores, was documented within 3 weeks in the majority of patients.