Question: what are the difference between the pathogenesis of megaloblastic and pernicious anemia?
Answer: Rarely, megaloblastic anemias are the result of medications or inherited defects in the transport/metabolism of vitamin B12 or folic acid. Pernicious anemia is a type of megaloblastic anemia in which the body isn't able to absorb vitamin B12 due to a lack of intrinsic factor in stomach secretions.