Question: how often do you take 500mg naproxen?
Answer: Always take your naproxen tablets with or just after a meal so you don't get an upset stomach. As a general rule in adults, the dose to treat: diseases of joints is 500mg to 1,000mg a day in 1 or 2 doses. muscle, bone disorders and painful periods is 500mg at first, then 250mg every 6 to 8 hours as required.