Question: is mukherjee and mukhopadhyay same?
Answer: Etymology. Note that "Mukherjee" evolved from the Sanskrit Mukhopadhyay (Bengali: মুখোপাধ্যায় Mukhopaddhae). Mukhopadhyay is from the purer Sanskrit form Mukhyopadhyay (in Sanskrit Mukhya – chief, Upadhyay – teacher, not necessarily a religious teacher).