Question: which one of the following enzymes is unique to gluconeogenesis?
Answer: The enzymes unique to gluconeogenesis are pyruvate carboxylase, PEP carboxykinase, fructose 1,6-bisphosphatase, and glucose 6-phosphatase. Starting from pyruvate, the reactions of gluconeogenesis are as follows: In the mitochondrion, pyruvate is carboxylated to form oxaloacetate via the enzyme pyruvate carboxylase.