Question: can prilosec cause kidney failure?
Answer: The FDA approved Proton Pump Inhibitors (PPIs), like Nexium and Prilosec, for use up to four weeks at a time. However, many people have taken Prilosec or Nexium every day for decades. Extended use of Prilosec and Nexium can cause severe kidney problems, such as Acute Interstitial Nephritis (AIN).