Question: do sertoli cells produce estrogen?
Answer: In fetal and immature animals, Sertoli cells are the main source of estrogens,5–7 and the expression of aromatase in Leydig cells is very low. ... Similar to Leydig cells, aromatase expression is relatively low in adult rat Sertoli cells,10 and Sertoli cell aromatase is negatively controlled by germ cells.