Question: is mtx a tnf inhibitor?
Answer: TNF inhibitors, whose mode of action (MoA) primarily targets monocytes and dendritic cells, and MTX, which inhibits lymphocytes, exert a synergistic therapeutic effect in RA. Tocilizumab has a broader effect than TNF inhibitors and mainly targets T and B lymphocytes, but also dendritic cells and monocytes.