Question: what is the difference between bisquick and flour?
Answer: 1 Answer. Self rising flour consists of flour, salt, and baking powder. Bisquick contains all of these ingredients plus hydrogenated vegetable shortening. One cup of Bisquick can be substituted by a mixture of one cup of flour, 1½ teaspoons of baking powder, ½ teaspoon of salt, and 1 tablespoon of oil or melted butter.