Question: are knocked up and this is 40 related?
Answer: Billed as a "sort-of sequel" to 2007's Knocked Up, the film brings back Jason Segel and Charlyne Yi to reprise their roles, but Debbie's (Mann) sister Alison (Katherine Heigl) and her unlikely beau Ben (Seth Rogen) -- who were at the heart of Knocked Up -- are never mentioned in the new comedy.