Question: is ezetimibe better than statins?
Answer: Ezetimibe lowers low-density lipoprotein cholesterol (LDL-C) by 15-20% when used alone2 as compared to 5-10% from doubling the dose of statin. A recent pooled analysis3 of 17 double-blind trials of patients who were already on a statin showed that the largest percent reductions in LDL-C were seen with adding ezetimibe.