Question: do you have to be put to sleep for a picc line?
Answer: During Your Procedure Your PICC will be put in by a doctor or nurse. First, you will get a numbing injection (shot) where your PICC will be placed. You won't need general anesthesia (medication to make you sleep). Once the area is numb, the doctor or nurse will make a small incision (surgical cut) in your upper arm.