Question: how often should you take ibuprofen 400 mg?
Answer: Ibuprofen Dosage Take ibuprofen with food or after meals if it seems to bother your stomach. Prescription doses of ibuprofen normally range between 400 mg to 800 mg, up every six to eight hours. In those cases, you should not take more than 3.2 g or 3,200 mg daily.