Question: what is the difference between st john's wort and 5 htp?
Answer: As an easy comparison between the two St John's wort claims to stop the reabsorption of serotonin while 5-HTP increases the amount of serotonin overall. According to research by Birdsall, 5-htp is the transitional metabolite of L-tryptophan (LT), the essential amino acid in the biosynthesis of serotonin [5].