Question: how to take doxycycline hyclate for acne?
Answer: Doxycycline comes in a tablet or a capsule you take by mouth with a full glass of water. For acne, the typical dosing for doxycycline is 50 mg or 100 mg twice daily or 100 mg once daily. But some forms of doxycycline are taken as 20 mg twice daily or 40 mg once daily.