Question: what is the difference between diabetes insipidus and siadh?
Answer: In SIADH, ADH is not suppressed resulting in water retention and significant electrolyte abnormalities. In DI, there is either decreased production of ADH (central DI), or normal ADH secretion with resistance in the kidneys to its effects (nephrogenic DI). The net result of DI is large volume diuresis of dilute urine.