Question: is hydroxyzine pamoate the same as benadryl?
Answer: Are Benadryl and Vistaril the Same Thing? Benadryl (diphenhydramine) and Vistaril (hydroxyzine pamoate) are antihistamines used to treat allergic skin reactions such as hives or contact dermatitis. Benadryl is also used to treat insomnia, motion sickness, and mild cases of Parkinsonism.