Question: what is the difference between phenylephrine and pseudo?
Answer: Are phenylephrine or pseudoephedrine the same? Phenylephrine and pseudoephedrine are both adrenergic agonists. Phenylephrine has primarily an affinity to only alpha-adrenergic receptors, while pseudoephedrine has an affinity to both alpha- and beta-adrenergic receptors. Their side effect profiles are very similar.