Question: what are the side effects of coming off tamoxifen?
Answer: Changes in the lining (endometrium) of your uterus. These changes may mean serious problems are starting, including cancer of the uterus. ... 
Blood clots in your veins or lungs. These can occur for up to 2–3 months after you stop taking tamoxifen. ... 
Stroke. ... 
sudden:
Cataracts. ... 
Liver problems.