Question: where is cephalon simaris located?
Answer: Cephalon Simaris (or referred to as Irmis by Cephalon Suda) is a Cephalon construct that resides within the Sanctuary Enclave, a room found in all Tenno Relays, which is accessible by visiting any Relay and then using Fast Travel from the Main Menu: default Esc → Fast Travel → Cephalon Simaris.