Question: when are you supposed to take niacin?
Answer: Niacin Dosage It should be taken as directed, sometimes at bedtime with a low-fat snack. Using a medication such as ibuprofen (Advil) or aspirin (Anacin, Bayer, Bufferin) 30 minutes prior to taking niacin may help prevent side effects such as flushing. Take niacin with a full glass of cold water.