Question: are ambrose and prudence siblings?
Answer: Diana Spellman — The wife of Edward, mother of Sabrina, sister-in-law of Zelda and Hilda, and aunt of Ambrose. Ambrose Spellman — Ambrose is the nephew of Zelda, Hilda, Edward and Diana, cousin of Sabrina, step-nephew of Father Blackwood, and step-cousin of Prudence.