Question: what is the best treatment for severe arthritis?
Answer: Painkillers. These medications help reduce pain, but have no effect on inflammation. ... 
Nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs reduce both pain and inflammation. ... 
Counterirritants. ... 
Disease-modifying antirheumatic drugs (DMARDs). ... 
Biologic response modifiers. ... 
Corticosteroids.