Question: is cetirizine the same as loratadine?
Answer: Zyrtec contains cetirizine hydrochloride, also called cetirizine HCL, while Claritin contains loratadine. Zyrtec and Claritin are second-generation antihistamines. They are less likely to make a person feel drowsy or otherwise affect alertness than older, first-generation antihistamines.