Question: how many times a day can you use nasal spray?
Answer: Directions for use of nasal decongestant sprays vary somewhat, but the label of oxymetazoline 0.05% spray (Afrin) advises patients aged >6 years to spray the product two to three times in each nostril not more often than every 10 to 12 hours, and not to exceed two applications in any 24-hour period.