Question: why moxifloxacin not used in uti?
Answer: Gemifloxacin and moxifloxacin are not effective for the treatment of UTIs because they do not achieve adequate concentrations in the urine. 5-7 The fluoroquinolones indicated for UTI are excreted in the urine as greater than 40% unchanged drug while gemifloxacin is less than 35% and moxifloxacin is only 20%.