Question: is trazodone linked to dementia?
Answer: Analysis revealed that the incidence of dementia was higher among trazodone users than that among matched antidepressant users (1.8 vs. 1.1 dementia cases per 100 person-years). The risk for dementia was also higher for trazodone users compared with other antidepressant users (HR = 1.8; 95% CI, 1.56-2.09).