Question: how long does it take for diarrhea tablets to wear off?
Answer: The half-life of loperamide is estimated to have a range of 9.1 to 14.4 hours. The average is around 10.8 hours. Blood concentration levels of loperamide are highest around five hours after someone takes it in capsule form and around 2.5 hours after taking liquid Imodium or generic loperamide.