Question: what antibiotics treat bacterial sinusitis?
Answer: Amoxicillin is considered the first-line antibiotic for most patients with acute bacterial rhinosinusitis. Trimethoprim/sulfamethoxazole (Bactrim, Septra) and macrolide antibiotics are reasonable alternatives to amoxicillin for treating acute bacterial rhinosinusitis in patients who are allergic to penicillin.