verificar como o exercicio modula diferentesaspectos bioquimicos, imunologicos e hormonais do organismo portador de tumor. Com essa serie de dadostornar-se-a mais facil a distincao dos efeitos do exercicio sobre o desenvolvimento do cancer.ABSTRACTEFFECTS OF EXERCISE UPON THE INCIDENCE AND DEVELOPMENT OF CANCERBACURAU, R.F. & COSTA ROSA, L.F.B.P.Rev. paul. Educ. Fis., Sao Paulo, 11(2):142-47, jul./dez. 1997146Cancer is a disease responsible for millions of deaths annually around the world. Severalstudies with animals and human beings suggest that the practice of exercises is related to a reduction in theincidence of this disease. The objective of this work was to review the literature about the effects of exerciseof different intensities upon the incidence and development of cancer. The review of literature demonstratedthat in spite of considerable evidences about a possible benefit effect of physical exercise (mainly moderate)in relationship to cancer, like the reduction of its evidence, there are yet, many controversial features aboutthis subject. This problem occurs mainly due to the fact that the major part of studies are of aepidemiological type. Finally, we concluded that more precise knowledge will only be obtained with theconduction of studies that control factors like intensity and duration of exercise.UNITERMS: Cancer; Moderate exercise; Intense exercise.REFERENCIAS BIBLIOGRAFICASAGGARWAL, B.B.; HENZEL, W.; MOFFAT, B.; KOHR, W.; HARKINS, R.N. Primary structure of humanlymphotoxin derived from 1788 lymphoblastoid cell line. Journal of Biological Chemistry, v.260, p.2334-44,1984.AGGARWAL, B.B.; MOFFAT, B.; HARKINS, R.N. Human lymphotoxin production by a lymphoblastoid cell line;purification and initial characterization. Journal of Biological Chemistry, v.259, p.686-91, 1984.BLAIR, S.N.; KOHL, H.W.; PAFFENBERGER, R.S.; CLARK, D.G.; COOPER, K.H.; GIBBONS, L.W. Physicalfitness and all-cause mortality: a prospective study of healthly men and women. JAMA, v.262, p.2395, 1989.BRINES, R.; HOFFMAN-GOETZ, L.; PEDERSEN, B.K. Can you exercise to make your immune system fitter?Trends in Immunology Today, v.17, p.252-60, 1996.BURANT, C.F.; BELL, G.I. Mammalian facilitative glucose transporters; evidence for a similar substrate recognitionsites in functionally monomeric proteins. Biochemistry, v.3, p.10414-20, 1992.BURT, M.E.; LOERY, S.F.; GORSCHBOTH, C.; BRENNAN, M.F. Metabolic alterations in a noncachetic animaltumor system. Cancer, v.47, p.2138-46, 1981.CALABRESE, L.H. Exercise, immunity, cancer, and infection. In: BOUCHARD, C.; SHEPARD, R.J.; STEPHENS, T.;SUTTON, J.R.; McPHERSON, B.D., eds. Exercise, fitness, and health: a consensus of current knowledge.Champaign , Human Kinetics, 1990. p.567-79.CANNON, J.G. Exercise and resistance to infection. Journal of Applied Physiology, v.74, n.3, p.973-81, 1993.CAREY, R.W.; PRETLOW, T.G.; EZDINLI, E.D.; HOLLAND, J.F. Studies on the mechanism of hypoglicemia in apatient with massive intraperitoneal leiomyosarcoma. American Journal of Medicine, v.40, p.458-96, 1966.CORI, C.F.; CORI, G.T. The carbohydrate metabolism of tumors II: changes in the sugar, lactic acid, and CO2-combining power of blood passing through a tumor. Journal of Biological Chemistry, v.66, p.397-405, 1925.DANERYD, P.; HAFSTROM, L.; SVANBERG, E.; KARLBERG, I. Insulin sensitivity, hormonal levels and skeletalmuscle protein metabolism in tumor-bearing exercising rats. European Journal of Cancer, v.31, p.97-103, 1995.DEVEREAUX, D.F.; REDGRAVE, T.G.; TILTON, M.; HOLLANDER, D.; DECKERS, P.J. Intolerance administeredlipids in tumor bearing animals. Surgery, v.96, p.414-9, 1984.DINARELLO, C.A. Interleukin-1. Review of Infectious Diseases, v.6, p.51-95, 1984.EKMAN, L.; KARLBERG, I.; EDSTROM, S.; LINDMARK, L.; SCHERSTEN, T.; LUNDHOLM, K. Metabolicalterations in liver, skeletal muscle, and fat tissue in response to different tumor