Aproveitando a perspectiva publicada incentivando o cuidado intensivo:http://www.medscape.com/viewarticle/869429Relembro os parceiros e clientes que a monitoração contínua associada pronta intervenção continua sendo meu padrão de abordagem, onde obtemos melhora sustentável. Um novo conceito construído com a observação de 9 milhões de pacientes durante 14 anos.O eixo causal foi relacionado com a vasculite auto-imune induzindo hipóxia e inflamação cerebral, com predominância entre as mulheres.Autoimmune Diseases Linked to DementiaPauline AndersonMarch 03, 2017A new study provides additional evidence linking autoimmune diseases to dementia, including Alzheimer's disease (AD).Researchers showed that compared with a control group admitted to the hospital for another reason, people hospitalized with an autoimmune disease were more likely to be later admitted with dementia."Fundamentally, this is an epidemiology study using the power of big numbers of patients to look at a hypothesis, namely that Alzheimer's disease may have an autoimmune component, and our bottom line in epidemiological and population terms is that yes, the study supports that hypothesis," study author Michael J. Goldacre, emeritus professor of public health, University of Oxford, United Kingdom, told Medscape Medical News.It's important for clinicians to recognize that their patients with multiple sclerosis, type 1 diabetes, rheumatoid arthritis, or other autoimmune disorders may have an increased risk for dementia, said Dr Goldacre.The study was published online March 1 in the Journal of Epidemiology & Community Health.Common Chronic DiseasesResearchers used the Hospital Episode Statistics database, which includes clinical, demographic, and administrative information on hospital admissions (including day cases) in England. They constructed retrospective cohorts of patients admitted to the hospital with a range of autoimmune diseases and followed them to see which patients were later admitted with a record of dementia.The 25 diseases on the list for evaluation included those that are common and chronic and for which there's an accepted autoimmune component. The list did not include type 1 diabetes because, as Dr Goldacre explained, he and his colleagues had already published a paper that linked diabetes with subsequent dementia.The researchers also constructed a control cohort of patients hospitalized with various other medical and surgical conditions and injuries.From April 1, 1998, to March 31, 2012, over 1.8 million people were admitted to the hospital with an autoimmune disease. The number in the different autoimmune groups ranged from 1019 for Goodpasture's syndrome (where antibodies attack the lungs and kidneys), to 316,043 for rheumatoid arthritis (RA). About 7 million people were included in the control cohort.The autoimmune disease cohort that eventually had the most dementia cases (48,146) was myxoedema (hypothyroidism). This condition "is quite common in elderly people, particularly women," commented Dr Goldacre.Overall, patients admitted to the hospital with an autoimmune disease were 20% more likely to have a subsequent admission for dementia than those without an admission for an autoimmune disease (adjusted rate ratio [RR], 1.20; 95% confidence interval [CI], 1.19 - 1.21).Of the 25 diseases studied, 18 showed significant positive associations with dementia at P < .05 (with 14 significant at P < .001), including multiple sclerosis (RR, 1.97; 95% CI, 1.88 - 2.07), psoriasis (RR, 1.29; 95% CI, 1.25 - 1.34), and systemic lupus erythematosus (RR, 1.46; 95%