and to limit these consequences to intended effects. This requires significant research on environmental models, risk management, as well as the theory, mechanisms, and experimental designs for built-in safeguard systems.Industry self-regulation should be designed in whenever possible. Economic incentives could be provided through discounts on insurance policies for MNT development organizations that certify Guidelines compliance. Willingness to provide self-regulation should be one condition for access to advanced forms of the technology.Distribution of molecular manufacturing development capability should be restricted, whenever possible, to responsible actors that have agreed to use the Guidelines. No such restriction need apply to end products of the development process that satisfy the Guidelines.Specific Design GuidelinesAny self-replicating device which has sufficient onboard information to describe its own manufacture should encrypt it such that any replication error will randomize its blueprint.Encrypted MNT device instruction sets should be utilized to discourage irresponsible proliferation and piracy.Mutation (autonomous and otherwise) outside of sealed laboratory conditions, should be discouraged.Replication systems should generate audit trails.MNT device designs should incorporate provisions for built-in safety mechanisms, such as: 1) absolute dependence on a single artificial fuel source or artificial "vitamins" that don't exist in any natural environment; 2) making devices that are dependent on broadcast transmissions for replication or in some cases operation; 3) routing control signal paths throughout a device, so that subassemblies do not function independently; 4) programming termination dates into devices, and 5) other innovations in laboratory or device safety technology developed specifically to address the potential dangers of MNT.MNT developers should adopt systematic security measures to avoid unplanned distribution of their designs and technical capabilities.There is one very important and simple method to insure the safe development of MNT: become involved in the debate. Regardles of your opionion, you need to both express it and stand behind it, in forums both public and virtual. Educate yourself -- we will provide the tools, right here. And if there is ever anything you need regarding information, just ask.Another great resource is The Center for Responsible Nanotechnology (CRN) A non-profit organization, formed to advance the safe use of molecular nanotechnology. CRN was founded by Chris Phoenix and Mike Treder in December 2002. The vision of CRN is a world in which nanotechnology is widely used for productive and beneficial purposes, and where malicious uses are limited by effective administration of the technology. Or go to the Google sci.nanotech Group and ask your questions."The principles of physics, as far as I can see, do not speak against the possibility of maneuvering things atom by atom. It is not an attempt to violate any laws; it is something, in principle, that can be done; but in practice, it has not been done because we are too big." - December 29th, 1959"In not too many decades we should have a manufacturing technology able to: Build products with almost every atom in the right place; Do so inexpensively; Make most arrangements of atoms consistent with physical law. Often called nanotechnology, molecular nanotechnology or molecular manufacturing, it will let us make most products lighter, stronger, smarter, cheaper, cleaner and more precise."