Set of procedures for supporting endodontic treatment for the maintenance of the aseptic chain, which underpin the philosophy of group therapy aimed at proservation biological integrity of the periapical tissue. The oral cavity is an area of the body with more diverse microbiota, and 1 ml of saliva from a normal individual in good health, contains about 750 million organisms. Some species of bacteria produce nearly one hundred generations in a period of 24 hours. There are cases where the dental pulp is free of microorganisms and there are times when it is heavily contaminated by them. The professional should always be aware and meditate on the aphorism. The provider is not responsible for what is in their field, but for what it brings on. So, throughout the endodontic treatment should be made to prevent or minimize the presence of microorganisms in field work during the surgery. (IN: FORP - BASICS OF TREATMENT ENDODONTIC) One way of maintaining consegiur this is the organization of the clinic desk and side table. Using sterile TNT: Auxiliary table: sterile instruments and equipment disinfected. Material disinfected with gauze soaked in alcohol 70%, by friction. Instrumental sterile Table clinic: Instrumental sterile. The therapeutic principle of any inflammatory disease usually characterized by identifying and eliminating the cause. In the case of periapical granulomas with adequate endodontic treatment characterized by filling the root canal and, if possible, of accessory canals, will be the elimination of the offending agent represented by the microbiota of infected root canals. Bacteria and their products that may remain in small quantities, compared to the potential early aggressive, tend to be neutralized by products used in endodontic therapy, based on biomechanical, along with the irrigating solution, especially antibiotics and calcium hydroxide. In 60 to 70% of cases of endodontic treatment of teeth with pulp necrosis and chronic periapical success is characterized by regression of the lesion over a few months of the radiographic point of view.However, the ossification process reorganization and apical periodontal tissue begins as soon as adequate endodontic treatment completed. The inflammatory exudate in a few days will be resorbed by inflammatory cells with tissue debris, and microbial cell. Inflammatory cells will be replaced in a few days and weeks to young proliferating cells arising from surrounding tissues such as periodontal ligament and endosteum. It is expected that over 3 to 4 weeks the tissue is in rapid process of structural reorganization and the inflammatory component is reduced to small pockets in order to clean these areas.Without the mediators of inflammation and its units osteoremodeladoras clasts are demobilized and return to be reabsorbed surfaces covered with cementoblasts proliferating from the surrounding area, returning to form tissue or cementoide osteocemento, reinserting periodontal fibers to restore a normal functional apical periodontium. . However, only a few months after the radiographic area can return to "normal." (IN: DENTAL PRESS) (IN: DENTAL PRESS) Case Study: History: Male, 32 years. He arrived at the office referred to the treatment endodotico element 36. Not refer pain and had no clinically visible changes. The vitality test was negative. Radiographic findings: