Caros leitoresCom a chegada do feijao transgenico na mesa dos brasileiros,prevista para 2016, esta na hora de ler com atencao o artigo recente intituladoBiosafety research for non-targetorganism risk assessment of RNAi-based GE plants.O artigo tem uma visao muito clara sobre a metodologia da avaliacao de risco e asconsideracoes que nos traz sobre iRNA sao muito importantes. Aqui esta o link:http://journal.frontiersin.org/article/10.3389/fpls.2015.00958/abstract(use o link download article a direita da tela do site)A compreensao das questoes e respostas mostradas nesteartigo seguramente eliminara qualquer receio que alguem possa ter sobre ofeijao da EMBRAPA resistente ao virus do mosaico dourado do feijoeiro, que usao mecanismo de interferencia de RNA para impedir a multiplicacao do virus nascelulas do feijao. A EMBRAPA e a CTNBio seguiram essencialmente os passosdelineados neste artigo. Em postagens anteriores analisamos a liberacao destefeijao e avaliamos parte de seus riscos. Os links estao abaixo.1) Rota ao dano pelo RNA de interferencia no feijaotransgenico da Embrapahttp://genpeace.blogspot.com.br/2013/04/rota-ao-dano-pelo-rna-de-interferencia.html2) A fonte de informacao correta para conhecer o feijao GMda EMBRAPAhttp://genpeace.blogspot.com.br/2011/08/fonte-de-informacao-correta-para.html3) Seguranca do feijao GM da Embrapa: sobre a improvavelexistencia de siRNA off targethttp://genpeace.blogspot.com.br/2013/05/a-interferencia-de-rna-e-um-processo.html4) Avaliacao de risco do feijoeiro transgenico: serenidadena conducao e consistencia dos resultados na CTNBiohttp://genpeace.blogspot.com.br/2011/10/avaliacao-de-risco-do-feijoeiro.htmlE tambem: a) o texto do Graziano: A historia do feijao GM como ela ehttp://genpeace.blogspot.com.br/2011/09/historia-do-feijao-gm-como-ela-e.htmlb) O feijaotransgenico da Embrapa e seguro, artigo de Francisco G. Nobrega e Maria LuciaZaidan Daglihttp://genpeace.blogspot.com.br/2011/10/o-feijao-transgenico-da-embrapa-e.htmlc) CTNBio refuta CONSEA quanto a seguranca do feijaotransgenico da EMBRAPAhttp://genpeace.blogspot.com.br/2011/08/ctnbio-refuta-consea-quanto-seguranca.html Dear Reader.Thediscovery of a genome editing system in bacteria and its use for editinggenomes of many organisms is transforming the way biotechnology is done.Likewise, the use of the gene drives (a form of stimulating biased inheritanceof particular genes to alter entire populations) opens up new applications forthe control of pests and invertebrate vectors or hosts, whenever they have ashort life cycle. But the knowledge of the two techniques is far from beingwidespread and sufficient, even among geneticists.In parallelwith the rapid development of genome editing and gene drives, regulatory issuesarise questioning the applicability of risk assessment procedures, asoriginally established for GMOs, and legal issues, such as the inclusion ofthis or that product in the regulatory framework of each country, regulatoryasynchrony, the ethical issues involved, etc.Anymeaningful discussion of these issues must be grounded in updated and qualityinformation. We therefore collected and offer the reader a set of selectedreferences that may be helpful in understanding both new technologies and inestablishing the applicability and eventual limits of present risk assessmentrules of new genome-edited or gene drive products.We split alittle arbitrarily texts in three subsets, the first devoted to the issue ofgenome editing by the CRISPR/Cas9 system, the second to gene drives and thethird for risk assessments available for the GM Aedes aegypti previously evaluated by CTNBio in Brazil andconsidered safe for commercial use in 2014. The latter references also includegeneral considerations on GM mosquitoes and emphasize the importance of newtools in vector control, particularly in mosquito-borne diseases.The textswhose links follow below can be of various kinds: scientific articles,technical reports, reviews written by scientists, reviews written by activists,conference presentations, etc. Many are available to the general public. Textsmarked with a square are suitable for a first approach to