ao melhor conhecimento de suas caracteristicas clinicas. As principais causas de PA em criancas sao doenca biliar e medicacoes, porem ate 1/3 dos pacientes pode nao ter etiologia definida no momento do diagnostico. O tratamento baseia-se em medidas de suporte e reposicao volemica em casos especificos, bem como na precoce introducao de NE, a depender das condicoes clinicas do paciente, de modo a reduzir a morbidade associada a doenca. O diagnostico precoce e o manejo apropriado podem contribuir para a melhor evolucao do paciente com PA e prevenir as complicacoes imediatas e tardias relacionadas. Referencias 1. Bradley EL 3rd. A clinically based classification system for acute pancreatitis: summary of the International Symposium on Acute Pancreatitis, Atlanta, GA, September 11 through 13, 1992. Arch Surg. 1993;128:586-90. [pubmed/open access] [crossref] 2. Nydegger A, Couper RT, Oliver MR. Childhood pancreatitis. J Gastroenterol Hepatol. 2006;21:499-509. [pubmed/open access] [crossref] 3. Bai HX, Lowe ME, Husain SZ. What have we learned about acute pancreatitis in children? J Pediatr Gastroenterol Nutr. 2011;52:262-70. [pubmed/open access] [crossref] 4. Park A, Latif SU, Shah AU, Tian J, Werlin S, Hsiao A, et al. Changing referral trends of acute pancreatitis in children: a 12-year single-center analysis. J Pediatr Gastroenterol Nutr. 2009;49:316-22. [pubmed/open access] [crossref] 5. Morinville VD, Barmada MM, Lowe ME. Increasing incidence of acute pancreatitis at an American pediatric tertiary care center: is greater awareness among physicians responsible? Pancreas. 2010;39:5-8. [pubmed/open access] [crossref] 6. Fagenholz PJ, Castillo CF, Harris NS, Pelletier AJ, Camargo CA Jr. Increasing United States hospital admissions for acute pancreatitis, 1988-2003. Ann Epidemiol. 2007;17:491-7. [pubmed/open access] [crossref] 7. Nydegger A, Heine RG, Ranuh R, Gegati-Levy R, Crameri J, Oliver MR. Changing incidence of acute pancreatitis: 10-year experience at the Royal Childrens Hospital, Melbourne. J Gastroenterol Hepatol. 2007;22:1313-6. [pubmed/open access] [crossref] 8. Lopez MJ. The changing incidence of acute pancreatitis in children: a single-institution perspective. J Pediatr. 2002;140:622-4. [pubmed/open access] [crossref] 9. Chang YJ, Chao HC, Kong MS, Hsia SH, Lai MW, Yan DC. Acute pancreatitis in children. Acta Paediatr. 2011;100:740-4. [pubmed/open access] [crossref] 10. Kandula L, Lowe ME. Etiology and outcome of acute pancreatitis in infants and toddlers. J Pediatr. 2008;152:106-10. [pubmed/open access] [crossref] 11. van Geenen EJ, van der Peet DL, Mulder CJ, Cuesta MA, Bruno MJ. Recurrent acute biliary pancreatitis: the protective role of cholecystectomy and endoscopic sphincterotomy. Surg Endosc. 2009;23:950-6. [pubmed/open access] [crossref] 12. Ozel A, Uysal E, Tufaner O, Erturk SM, Yalcin M, Basak M. Duodenal duplication cyst: a rare cause of acute pancreatitis in children. J Clin Ultrasound. 2008;36:584-6. [pubmed/open access] [crossref] 13. Ohno Y, Kanematsu T. Annular pancreas causing localized recurrent pancreatitis in a child: report of a case. Surg Today. 2008;38:1052-5. [pubmed/open access] [crossref] 14. Hwang SS, Paik CN, Lee KM, Chung WC, Jang UI, Yang JM. Recurrent acute pancreatitis caused by an annular pancreas in a child. Gastrointest Endosc. 2010;72:848-9. [pubmed/open access] [crossref] 15. Tzetis M, Kaliakatsos M, Fotoulaki M, Papatheodorou A, Doudounakis S, Tsezou A, et al. Contribution of the CFTR gene, the pancreatic secretory trypsin inhibitor gene (SPINK1) and the cationic trypsinogen gene (PRSS1) to the etiology of recurrent