semaj83/ctmatch_classification huggingface dataset:
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 12.0-999.0,  Allergic Asthma Allergic Rhinitis Allergic asthma or allergic rhinitis age 12+  smokers
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 1.0-45.0,  Respiratory Sounds Patient and/or parents/guardian signed informed consent Patients with cough or shortness of breath  Chest tubes Skin lesions precluding attachment of sensors Respiratory distress Pregnant women
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 0.25-2.0,  Asthma age 3-23 months be delivered at >=37 weeks first wheezing episode written informed consent from guardian  chronic illness other than atopy previous systemic or inhaled corticosteroid treatment participation to another study varicella contact if previously intact need for intensive care unit treatment, or poor understanding of Finnish
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 0.5-16.0,  Aspirated Foreign Body of Lower Respiratory Tract age between 6 months and 16 years suspicion of a foreign body aspiration health care assurance information of parents  emergency situation certainly of foreign body presence delay for CT Scan realization longer than 24 hours no speaking French parents parents refusal
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 18.0-50.0,  Asthma Hypersensitivity for healthy controls Normal lung function, defined as (Knudson 1976/1984 predicted set) FVC of > 80 % of that predicted for gender, ethnicity, age and height FEV1 of > 80 % of that predicted for gender, ethnicity, age and height FEV1/FVC ratio of > .75 Oxygen saturation of > 94 % and normal blood pressure (Systolic between 150 Diastolic between 90-60 mm Hg) Symptom Score no greater than 6 (out of a possible 24) for total symptom score with a value no greater than 2 for any one score Negative methacholine inhalation challenge as performed in the screening protocol. (Less than a 20% decrease in FEV1 at a maximum methacholine concentration of 10 mg/ml) --Negative pregnancy test for females Negative allergy skin test (AST) for allergic asthmatics also  Any chronic medical condition considered by the PI as a contraindication to the exposure study including significant cardiovascular disease, diabetes requiring medication, chronic renal disease, or chronic thyroid disease Physician directed emergency treatment for an asthma exacerbation within the preceding 12 months Use of systemic steroid therapy within the preceding 12 months for an asthma exacerbation. All use of systemic steroids in the last year will be reviewed by a study physician Use of inhaled steroids, cromolyn or leukotriene inhibitors (montelukast or zafirlukast) except for use of cromolyn exclusively prior to exercise Use of daily theophylline within the past month Use of tricyclics and MAO inhibitors Pregnancy or nursing a baby Cigarette smoking > 1 pack per month Nighttime symptoms of cough or wheeze greater than 1x/week at baseline (not during a clearly recognized viral induced asthma exacerbation) which would be characteristic of a person of moderate or severe persistent asthma as outlined in the current NHLBI guidelines for diagnosis and management of asthma Exacerbation of asthma more than 2x/week which would be characteristic of a person of moderate or severe persistent asthma as outlined in the current NHLBI guidelines for diagnosis and management of asthma
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 3.0-10.0,  Asthma All 6 must be met Physician-diagnosed asthma (based on caregiver report with validation from the child's physician) > 2 ED visits or > 1 hospitalization for asthma within past 12 months Mild persistent to severe persistent asthma based on NHLBI guidelines (7-9) having any 1 of the following An average of > 2 days per week of asthma symptoms > 2 days per week with rescue medication use (albuterol, xopenex) OR > 2 days per month of nighttime symptoms Age > 3 and < 10 years Reside in Baltimore Metropolitan area Not currently participating in another asthma study or sibling enrolled in PAAL study  Inability to speak and understand English No access to a working phone or alternate phone for follow-up surveys Co-morbid respiratory condition including cystic fibrosis, chronic lung disease (BPD), lung cancer, tracheostomy that could interfere with the assessment of asthma-related outcome measures Children residing in foster care or where consent cannot be obtained from a legal guardian
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 18.0-39.0,  Asthma Personal history of asthma, eczema, allergic rhinitis or a history of asthma, eczema, allergic rhinitis in the biological father of the child Gestational age between 10 and 18 weeks at the time of randomization Maternal age between 18 and 39 years Not a current smoker English or Spanish speaking Intent to participate for the full 4 years (through Pregnancy and then until the 3rd birthday of the child)  Not meeting Gestational age greater than 18 weeks Presence of chronic medical conditions Taking vitamin D supplements containing more than 2000 IU/day of vitamin D3 Multiple gestation pregnancy (twins, triplets) Pregnancy achieved by assisted reproduction techniques (e.g., IUI, IVF)
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 6.0-9.0,  Bronchial Asthma Clinical diagnosis of bronchial asthma Must be able to swallow tablets  Steroid inhalation or ingestion
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Avian Influenza Virus Diseases Be at least 18 years old Be willing to participate by signing a consent form, completing the study questionnaire, and providing a blood sample  Less than 18 years old Any known immunosuppressive condition or immune deficiency disease (including HIV infection), or ongoing receipt of any immunosuppressive therapy. (Note that we have chosen to such populations because of their increased risk of acquiring infections, they are relatively few, and are not representative of a national sample) Any individual with unknown poultry exposure status, or who was exposed to poultry more than 5 years ago
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 6.0-14.0,  Asthma Allergic Rhinitis children with intermittent asthma and allergic rhinitis  children with acute respiratory symptoms in the last 4 weeks children with nasal polyposis or bronchial or respiratory tract infections children with a severe exacerbation of asthma resulting in hospitalization during the last month
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 3.0-10.0,  Asthma (all 4 must be met) Physician-diagnosed asthma (based on parent report) Persistent asthma (criteria based on NHLBI guidelines). Any 1 of the following An average of >2 days per week with asthma symptoms >2 days per week with rescue medication use >2 days per month with nighttime symptoms ≥2 episodes of asthma during the past year that have required systemic corticosteroids Age ≥3 and ≤10 years Attending school in participating Rochester City School District preschools or elementary schools  Inability to speak and understand English. (*Parents unable to read will be eligible, and all instruments will be given verbally.) No access to a working phone for follow-up surveys (either at the subject's home or an easily accessible alternate phone number) Family planning to leave the school district within fewer than 6 months The child having other significant medical conditions, including congenital heart disease, cystic fibrosis, or other chronic lung disease, that could interfere with the assessment of asthma-related measures Children in foster care or other situations in which consent cannot be obtained from a guardian
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Allergic Asthma Allergic Rhinitis Subjects over 18 years old with allergic asthma and/or allergic rhinitis who are beginning allergen desensitization  Smokers Subjects of dimished capacity
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Asthma male or female to 65 years of age non smoker beta agonist naive for at least 14 days baseline FEV1 at least 70% predicted no respiratory tract infection or allergen exposure (if atopic) within 4 weeks of visit 1  poorly controlled asthma pregnant or lactating women
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Asthma Male or female subjects with history of mild atopic asthma between 18 and 60 years-of-age Body mass index (BMI) between 18 and 35 kg/m2 Normal or clinically acceptable physical examination (PE), clinical laboratory values, and ECG; clinically acceptable PE includes history of mild atopic asthma Used only inhaled short-acting β2-agonists infrequently to treat asthma No current exposure to allergens to which subject experiences asthmatic responses No other lung disease, exacerbations of asthma or lower respiratory tract infections for at least 6 weeks prior to screening Positive skin prick test to common aeroallergens at screening Additional apply  History or evidence of a clinically significant disorder (including psychiatric), condition or disease that would pose a risk to subject safety or interfere with the study evaluation, procedures or completion History or current medical conditions that are contraindicated for methacholine challenge, such as myocardial infarction or stroke within previous 3 months, known cardiac disease, uncontrolled hypertension and aortic or cerebral aneurysm Evidence of active or suspected bacterial, viral, fungal or parasitic infections within past 6 weeks Subject has know type I/II diabetes History of residential exposure to tuberculosis or has a positive PPD or QuantiFERON test within 4 weeks before randomization Subject who has history of malignancy of any type within 5 years prior to enrollment Subjects tested positive for drugs/alcohol or nicotine use at screening Subjects tested positive for HIV, Hep B or Hep C Additional apply
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 6.0-11.0,  Asthma Subjects will females (6 to 9 years of age) and males (6 to 11 years of age) All subjects must have a history of physician diagnosed mild intermittent or mild persistent asthma as documented by PCP medical record or detailed history by study investigator All subjects must have a height within normal limits (5th to 95th percentile) and no history of abnormal growth as assessed by medical history All subjects must be pre-pubertal (Tanner Stage 1 Sexual Maturity) as assessed by physical examination Subjects may be on current treatment with montelukast as this drug does not affect growth. If a subject is on montelukast at screening/baseline, they will remain on a stable dose throughout the study Subjects must be willing to comply with study requirements  Subjects will be excluded if they have asthma greater than mild persistent severity as defined by NHLBI guidelines Subjects will be excluded if they used any systemic or nasal steroids within the past 60 days Subjects will be excluded if they had more than one burst of systemic steroids within the past year Subjects will be excluded if their baseline FEV1 is < 80% predicted Subjects will be excluded if they have any other serious systemic disease other than asthma Subjects will be excluded if they have taken any medication known to affect growth i.e. ADHD medications within the past 60 days Subjects will be excluded if they have a history of allergy to any of the study medications, milk protein or lactose Subjects will be excluded if they have active chickenpox or measles or recent exposure to chickenpox or measles Subjects will be excluded if they have any history of tuberculosis of the respiratory tract Subjects will be excluded if they have any active fungal, bacterial, viral or parasitic infections
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 12.0-65.0,  Asthma Written informed consent Adolescents aged 12-17 years & adults aged 18-65 years (both inclusive) Documented clinical history of severe asthma requiring prednisone/prednisolone therapy, high-intensity treatment ICS, OCS, LABA Stable OCS dose for ≥7 days before Screening Visit & during Screening Period At least 80% compliant w/regular asthma medication per investigator at end of Screening Period Documented asthma reversibility within 5 yrs prior to/during Screening Period, or diagnosis of asthma that is incontrovertible per investigator Ability to use nDPI correctly, per investigator's review of completed inhaler operation checklist Ability to use eDiary correctly, assessed by investigator at end of Screening Period Ability to comply w/study procedures, including blood sampling Ability to perform technically satisfactory pulmonary function tests
Patient description: A 4 year old boy presents to the emergency room with wheezing. He has had a history of allergic rhinitis, but no history of wheezing. His mother reports that 5 hours ago patient was playing in the backyard sandbox when she heard him suddenly start coughing. The coughing lasted only moments, but he has been audibly wheezing since. Mother was concerned, because his breathing has not returned to normal, so she brought him to the ED. On exam, the child is playful and well appearing. Wheezing is heard in the mid-right chest area. O2 sats are 100% on room air.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  CHRONIC OBSTRUCTIVE PULMONARY DISEASE ASTHMA HEALTHY SUBJECTS COPD patients, either male or female, over the age of 40 with a clinical diagnosis of COPD with airflow obstruction(FEV1/FVC<0.7) and post-bronchodilator FEV1>50% predicted, gas trapping (on lung volume testing), and decreased carbon monoxide transfer factor Healthy subjects will be nonsmokers(or exsmokers stopped 5 years ago), will have no respiratory disease, normal spirometry and be age-matched to the COPD patients Asthmatic subjects, either male or female, over the age of 18 with a clinical diagnosis of Asthma with airflow obstruction (FEV1/FVC<0.7) All patients should be capable of giving informed consent  Oral corticosteroids taken within last month Current involvement (or involvement in the last 4 weeks)in clinical trials assessing investigational medicinal products Previous adverse reaction to short or long acting β2 agonist Any subject with a contraindication to taking inhaled beta2-adrenoceptor agonists (especially salbutamol) as listed in the British National Formulary will not be entered into this study Those who have experienced an acute respiratory exacerbation requiring emergency room treatment and/ or hospitalisation within four weeks of visit 1 (screening visit) Pregnant or breastfeeding women Subjects unable to give Informed Consent