semaj83/ctmatch_classification huggingface dataset:
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-75.0,  Dyslipidemia Signed informed consent Males or females aged 18 to 75 years. Female patients must be non-fertile. To be considered as non-fertile, females must fulfil the following Non-nursing and non-pregnant 12 months prior to enrolment Not of child bearing potential ie, either documented irreversible surgically sterile (bilateral oophorectomy or hysterectomy is acceptable, but not tubal ligation) or post-menopausal. Post-menopausal is defined as serum follicle-stimulating hormone (FSH) levels in the post-menopausal range combined with amenorrhea for more than 1 year in a woman above 50 years of age, or amenorrhea for more than 2 years below 50 years of age Patients with hypercholesterolemia treated with stable doses of the below listed lipid lowering medication for at least 3 months prior to randomization Atorvastatin not more than 20 mg/day or Simvastatin not more than 40 mg/day LDL-cholesterol > 3.0 mmol/L (Week -1) Subject able and willing to comply with all study requirements At randomization, diet as instructed by the investigator during the last 4 weeks prior to randomization and willingness to follow these instructions throughout the study  Cholesterol lowering agents other than the defined statins History of somatic or psychiatric disease/condition, which may interfere with the objectives of the study as judged by the investigator Clinically significant illness or clinically relevant trauma within 2 weeks before the administration of the investigational product as judged by the investigator Chronic (> 3 months) pain condition requiring daily medication with pain killers Glycosylated haemoglobin (HbA1c) > 7.0% Diabetes requiring medication other than metformin Clinically abnormal physical findings and laboratory values as judged by the investigator and abnormal resting ECG, eg, QTc interval > 450 msec Body Mass Index of ≥ 40 kg/m2 Resent history (< 3 month) of stroke or transient ischemic attacks History of seizure disorder, except febrile convulsions
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Turner Syndrome Turner syndrome verified by karyotyping  untreated hypothyroidism or hyperthyroidism present or past malignant diseases clinical liver disease treatment with drugs known to interfere with bone metabolism (e.g. glucocorticoids)
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 20.0-60.0,  Graves Disease Patients with newly diagnosed hyperthyroid Graves' disease  If the patient had been treated previously diabetes, kidney, or liver disease
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Electric Stimulation Therapy Obesity Weight Loss Eating BMI greater than or equal to 30 kg/m(2) Age 18-60 years. Women who are post-menopausal will be excluded from the study due to changes in their metabolism that could affect weight loss. We will set the cutoff at age 60 so that the age difference between the men and women is not too great for analysis purposes. Minors under the age of 18 will be excluded because the time requirements of the study are such that they would interfere with school schedules. Additionally, while the risks of TDCS are minimal, there haven t been studies showing how TDCS might affect the growing brain Healthy, as determined by medical history, physical examination, and laboratory tests Right-handedness (because the treatment will be given to the left dorsolateral prefrontal cortex and the evidence accumulated in this region was only in right-handed individuals) Weight stable (plus or minus 5 percent) for last 3 months  Weight less than 350 lbs, as this is the weight limit of the DXA machine Type 2 diabetes (according to the World Health Organization diagnostic criteria) Endocrine disorders (Cushing s disease, pituitary disorders, and hypo and hyperthyroidism) Chronic pulmonary disorders, including chronic obstructive pulmonary disease that would limit ability to follow the protocol (investigator judgment) and obstructive sleep apnea syndrome; only subjects with mild or exercise-induced asthma on no medications or on beta-adrenergic agonists only (such as albuterol) will be allowed to enter the study (provided use of these agents is not required for 1 week before study entry) Cardiovascular diseases (coronary heart disease, heart failure, arrhythmias, and peripheral artery disease) Hypertension (blood pressure measurement higher than 140/90 mmHg on 2 or more occasions or use of anti-hypertensive medications) Diagnosed gastrointestinal diseases, including inflammatory bowel diseases (e.g. Crohn s disease and ulcerative colitis), malabsorption syndromes (e.g. celiac disease), gastric ulcer (active); only subjects with gastro-esophageal reflux will be allowed to enter the study Liver disease (cirrhosis, active hepatitis B or C, and AST or ALT greater than or equal to 1.5 times normal) Renal disease (serum creatinine concentrations greater than or equal to 1.5 mg/dl and/or overt proteinuria)
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-85.0,  Healthy Body mass index (BMI) < 30 kg/m2 Age 18-45 yr; or Age 65-85 yr  Those taking medications known to affect substrate metabolism or medications that may confound the findings from our study (synthetic steroids, glucocorticoids etc.) Those with evidence of significant organ system dysfunction (e.g. diabetes mellitis, cirrhosis, hypo or hyperthyroidism; hypertension) Body mass index > 30 kg/m2 Age <18 yr, 45-65 yr or > 85 yr Those performing >1.5h of exercise/wk
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Graves Disease Hyperthyroidism Graves hyperthyroidism in remission after ATD  Age < 18, severe concomitant disease
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-85.0,  Helicobacter Pylori Infected Patients Thyroid Cancer Patients Hyperthyroidism Adult patients between the ages of 18 and 80 Patients with diagnosed thyroid disease referred for thyroid scan or treatment with radioactive iodine (131I) Patients who provide informed consent  Patients without diagnosed thyroid disease Patients who are pregnant or breast feeding Patients who have received previous treatment for H. pylori infection Patients taking proton pump inhibitors Patients with recent or current use of antibiotics Patients allergic to iodine (131I)
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Atrial Fibrillation Heart Failure Age ≥ 18 years, < 80years NYHA II-IV symptoms Impairment of left ventricular systolic function (left ventricular ejection fraction estimated as ≤ 35% by radionuclide ventriculography) Documented AF lasting for at least 7 days (persistent or permanent AF)  CRT or ICD device implanted in the previous 6 months AV nodal ablation within previous 3 months Prior AV nodal ablation or complete heart block with a single chamber pacemaker Contraindication to anticoagulation Persistent thrombus in the left atrium despite anticoagulation Active malignancy Cerebrovascular accident within the previous 6 months Reversible causes of AF including thyroid disorders, alcohol, recent surgery Reversible causes of heart failure including acute myocarditis or alcohol Cardiac events including myocardial infarction (MI), percutaneous coronary intervention (PCI), valve or coronary bypass surgery within the previous 3 months
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Graves Disease Hyperthyroidism Adult patients with a clinical diagnosis of Graves Disease Patients who have selected surgical resection as treatment of their Graves Disease Prior use of anti thyroid medication so that patient is clinically and biochemically euthyroid  Patients deemed unfit for surgery by operating surgeon or anesthesist Patients who are clinically hyperthyroid or have T3 or T4 levels 2X the upper limit of normal
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Goiter Criterion a bilateral non-toxic multinodular goiter with normal appearing on ultrasound of the neck posterior aspects of both thyroid lobes  multinodular goiter involving posterior aspect/s of thyroid lobe/s suspicion of thyroid cancer previous thyroid surgery thyroiditis subclinical or clinically overt hypothyroidism or hyperthyroidism pregnancy or lactation age < 18 years or > 65 years ASA 4 grade (American Society of Anesthesiology) inability to comply with the follow-up protocol
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Thyroid Cancer for patient participants Individuals with papillary thyroid carcinoma who have had complete resection of their thyroid at surgery (total or near-total thyroidectomy, or hemi [subtotal] with completion thyroidectomy)on or after September 1, 2009 Age at time of first thyroid cancer surgery must be at least 18 years or older The papillary thyroid cancer TNM pathologic stage must be pT1 or pT2, N0 (or Nx), M0 (or Mx) (TNM stage, AJCC VI) (ie. primary tumor size 1-4 cm, no known positive lymph nodes at the time of primary surgery, no extension of the tumor outside the thyroid, no venous or lymphatic invasion, and no known distant metastases at primary surgery, with no tall cell features, as per surgical pathology report) Must be able to communicate in spoken and written English Must be able to use a computer Must be able to provide informed consent on one's own (without any need for translation)  for patient participants Participants not meeting Concurrent diagnosis of medullary or anaplastic or poorly differentiated thyroid cancer or thyroid lymphoma Prior radioactive treatment for thyroid cancer Individuals who have been taken off their thyroid hormone for testing or treatment, will not be eligible for the study while off this medication Individuals who are unwilling for investigators to confirm their pathologic stage of disease through review of pathology report(s) will be ineligible for the study for the physician feedback component of this study Physicians and surgeons caring for thyroid cancer patients, in active practice at University Health Network in Toronto, Ontario, Canada
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-85.0,  Multinodular Goitre Grave's Disease Thyroid Nodule multinodular goiter Grave's disease thyroid nodule  thyroid carcinoma reoperative surgery
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Thyroid Neoplasm Advanced/poorly differentiated thyroid cancers of follicular cell origin that have no uptake (less than 1%) on radioiodine scan or are unresponsive to radioiodine therapy. Unresponsiveness to radioiodine therapy is defined as a patient s thyroglobulin not falling to less than 2ng/ml within 6 months after previous radioiodine ablative treatment Extensive (invasive) loco-regional tumor mass and/or metastatic spread, rendering patient inoperable Thyroglobulin (Tg) levels greater than or equal to 100 ng/ml in the absence of Tg antibodies. Patients who are Tg-antibody (Tg-Ab) positive may be included despite a lower Tg level if they have detectable disease on cross sectional imaging. (The presence of Tg-Ab may lead to falsely low Tg levels and therefore render the Tg a less sensitive marker of disease. However, Tg-Ab has been shown to also act as a tumor marker, and will be used as an endpoint for the study in patients who are Tg-Ab positive.) Within 18 months of enrollment, patients must have had an RAI scan, showing no or therapeutically insignificant RAI uptake (less than or equal to 1%) Initial therapy must have included total/near-total thyroidectomy and RAI ablation therapy Patients must have had no chemotherapy, radiotherapy, or biologic therapy for their malignancy in the month prior to treatment and must have recovered from all side effects of therapeutic and diagnostic interventions Greater than or equal to 18 years of age Must be able to understand and sign the Informed Consent Document Clinical performance status of ECOG less than or equal to 1 Life expectancy of greater than three months  Allergy to valproic acid Current coexisting malignancy other than basal cell carcinoma Women of child-bearing potential who are pregnant or breastfeeding Valproic acid is a known teratogen, causing primary neural tube defects, facial abnormalities, and skeletal malformation; therefore pregnant women will be excluded. Additionally, patients that become pregnant while on study protocol will be discontinued immediately Active systemic infections, coagulation disorders or other major medical illnesses Patients taking tolbutamide, warfarin, zidovudine, benzodiazapines, clonazepam, diazepam Seizure disorder
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 16.0-60.0,  Graves' Disease Graves' disease patients. Healthy people  Pregnancy. <16 years old or > 60 years old
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 8.0-90.0,  Hypothyroidism Exophthalmos a typical clinical symptoms of Graves disease, diffuse goiter, eye signs (including exophthalmos), thyroid function (FT3, FT4, rTSH) and thyroid autoantibodies and imaging examinations to confirmed  treatment contraindications, those who have not signed the informed consent, failure to complete treatment and follow-up estimates of patients and patients not suitable for radionuclide therapy
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 15.0-85.0,  Thyrotoxicosis Peak Systolic Velocity of Superior Thyroid Artery Thyroiditis Graves Disease newly diagnosed without taking any antithyroid drug or beta receptor blocker with TSH level below the lower limits of reference range is willing to be enrolled  unwilling taking antithyroid drug or beta receptor blocker taking foods or medicine rich in iodine in 8 weeks women with pregnant or lactation
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-55.0,  QoL Before and After 9 Month of Medical Treatment of Graves´Thyrotoxicosis Potential Effect of Selenium New diagnose of autoimmune thyrotoxicosis biochemically proven with increased thyroxin low TSH and elevated TRAb/or positive scintigraphy Age 18 Willing to participate -  No previous head trauma No difficulties with swedish language No medication which could affective neuropsychological testing No planned or ongoing pregnancies Normal intellectual capacity No severe ophthalmopathy, or other severe disease
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 20.0-64.0,  Irritable Bowel Syndrome Patients meeting the Rome III Diagnostic Loose (mushy) or watery stools within the last 3 months Abdominal discomfort and/or pain during their non-menstrual period  Patients with a history of surgical resection of the stomach, small intestine or large intestine Patients with a history or current diagnosis of inflammatory bowel disease (Crohn's disease or colitis ulcerative) Patients with a history or current diagnosis of colitis ischemic Patients with a current diagnosis of enteritis infectious Patients with a current diagnosis of hyperthyroidism or hypothyroidism Patients who are currently participating in another clinical trial (including a post-marketing clinical study) or those who participated in another clinical trial (including a post-marketing clinical study) within 12 weeks before the study Patients with a history or current diagnosis of malignant tumor Patients with a history of abuse of drugs or alcohol within 1 year or those who are currently abusing them
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-40.0,  Healthy Middle-aged Subjects Age Range Was 18 to 31 Years Caucasian Whites Males and Females healthy middle-aged subjects  volunteers with systemic or ocular diseases
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 40.0-69.0,  Overweight and Obese by BMI women aged 40-69 overweight or Class I & II obese (BMI 28 to 39.9)or BMI 40 to 45 with physician clearance state a commitment to losing weight speak and read English able to communicate over the telephone able to use a computer with minimal assistance and complete electronic forms and surveys have access to and are able to access the Internet commitment to access the website as required by the research intervention including weekly self-reporting of calories and fat grams, weekly self-reporting of physical activity, pedometer steps, and body weight, and weekly (or more often) participation in other website components as determined by group to which randomized and phase of intervention have or are willing to obtain an email account have access to a DVD player  diagnosed with Type 1 diabetes diagnosed with Type 2 diabetes and require insulin ≥ 10% weight loss in last six months enrolled in a weight loss management program enrolled in a formal program of cardiac rehabilitation or undergoing physical rehabilitation taking medications that affect weight loss or weight gain other physical or medical restrictions that would preclude following the minimum recommendations for moderate physical activity and healthy eating