semaj83/ctmatch_classification huggingface dataset:
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Sarcomas Procurement Diagnosis of refractory or metastatic GD2-positive sarcoma not responsive to standard treatment. Patients with osteosarcoma do not require GD2 testing of their tumor as osteosarcomas are uniformly GD2 positive Either previously infected with varicella zoster virus(VZV; chicken pox) or previously vaccinated with VZV vaccine Karnofsky/Lansky score of greater than or equal to 50 Informed consent explained to, understood by and signed by patient/guardian. Patient/guardian given copy of informed consent Treatment Diagnosis of refractory or metastatic GD2-positive sarcoma not responsive to standard treatment. Patients with osteosarcoma do not require GD2 testing of their tumors as osteosarcomas are uniformly GD2 positive Recovered from the acute toxic effects of all prior chemotherapy Karnofsky/Lansky score of greater than or equal to 50 Bilirubin less than or equal to 3x upper limit of normal, AST less than or equal to 5x upper limit of normal, Serum creatinine less than or equal to 2x upper limit of normal, Hgb greater than or equal to 9.0 g/dl, ANC>500/uL, platelets > 50,000/uL  Procurement • Known primary immune deficiency or HIV positivity Treatment Severe intercurrent infection Known primary immune deficiency or HIV positivity Pregnant or lactating History of hypersensitivity reactions to murine protein-containing products Known allergy to VZV vaccine
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 18.0-30.0,  Hyperalgesia Asymptomatic subjects who met the criterion of being between 18 and 30 years old  rheumatologic diseases or any type of cancer, cervical surgery in the past, whiplash trauma and undergoing any type of treatment like physical therapy, manual therapy, osteopathy, chiropraxis, acupuncture during the last three months. All patients recruited for the study complained of pain localized in the neck and/or head region. Initial screening was accomplished by telephone and eligible persons attended a evaluation appointment development of systemic or degenerative diseases subjects with symptoms of depression according Beck's questionnaire pain in any area between the lower back and head in the last 9 months traumatic event in the past 12 months history of neck or face pain in the last 6 months
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Septic Arthritis Major patients hospitalized in Rheumatology, Infectiology, Orthopedy Department (hospital of Nantes, of La Roche sur Yon and of Saint-Nazaire) with a septic arthritis of shoulder, or elbow, or wrist , or hip, or knee, or ankle on native joint, with positive microbiologic culture joint fluid or positive hemoculture; the diagnosis was based on positive histology or imagery with an inflammatory joint fluid if the microbiologic cultures (hemoculture or joint effusion) were negative  Presence of material on the targeted joint Age < 18 years old Patients under guardianship Pregnancy
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 50.0-999.0,  Total Knee Arthroplasty Pain Nerve Blocks Age > 50 years Patients set to cemented Total knee arthroplasty in spinal block Patients who have given written informed consent to participate in the study after having understood the contents of the protocol and limitations fully Illness score 1-3  Patients who can not cooperate with the investigation Patients who do not understand or speak Danish Patients receiving immunosuppressive therapy Patients with a treatment-dependent diabetes mellitus Patients with known neuropathy in the lower limbs Allergy to those drugs used in the study Alcohol and / or drug abuse the investigator's opinion Patients who can not tolerate Non steroid analgesic drugs Use of strong opioid several times a day (morphine, ketogan, Oxynorm, methadone, fentanyl)
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 45.0-80.0,  Osteoarthritis Pain Age 45 to 80 years old, inclusive Clinical diagnosis of osteoarthritis in one target knee based on the following American College of Rheumatology (ACR) Knee Pain At least 1 of 3 Age > 50 years Morning stiffness lasting < 30 minutes Crepitus on motion Osteophytes on radiograph Symptoms associated with osteoarthritis of the knee (including pain) for ≥ 6 months prior to Screening Knee pain associated with osteoarthritis, which required NSAID or other therapy for ≥ 15 days during the preceding month  General Women of childbearing potential, or men whose sexual partner(s) is a woman of childbearing potential may not be entered into the study if They are or intend to become pregnant (including use of fertility drugs) during the study They are nursing They are not using an acceptable, highly effective method of contraception until all follow-up procedures are complete. (Acceptable, highly effective forms of contraception are defined as: oral contraception, intrauterine device, systemic [injectable or patch] contraception, double barrier methods, naturally or surgically sterile, strict abstinence or partner has been sterilized. If hormonal-based birth control is being used, subject or subject's sexual partner(s) must be on a stable-dose for ≥ 3 months prior to the Baseline visit and maintained at the same dosing level throughout the 9-week clinical trial.) Body Mass Index (BMI) over 40 A history of osteoarthritis symptoms that are completely non-responsive to non-steroidal anti-inflammatory drugs (NSAIDs) at the discretion of the Investigator Planned change (increase or decrease) in subject's level of physical activity (e.g., aerobic or anaerobic exercise) during the 6-week Treatment Period following randomization Enrollment in any trial and/or use of any Investigational Drug or device within the immediate 30-day period prior to the Baseline visit Enrollment in any study previously sponsored by Olatec Industries LLC, specifically Study OLT1177-01 or OLT1177-02
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 5.0-12.0,  Cerebral Palsy age 5 to12 years inclusive assessed as GMFCS Levels II or III able to follow testing instructions, and participate in a minimum of 30 minutes of active PT able to reliably signal pain, fear and discomfort have passive range of motion (ROM) of hips and knees within minimum range requirement for Lokomat (hip and knee flexion contracture < 10 degrees, and knee valgus < 40 degrees) client of Child Development Program at Holland Bloorview able to commit to attendance of twice weekly for eight weeks (to support the primary efficacy analysis)  a fixed knee contracture > 10 degrees, knee valgus >40 degrees such that robotic leg orthosis will not be adaptable to lower limbs hip instability/subluxation > 45% orthopaedic surgery within the last 9 months (muscle) or 12 months (bone) Botulinum toxin-A (BTX-A) injections to lower limb in the last 4 months inability to discontinue BTX-A for period of 6 months (during trial) due to concerns about ROM or pain severe spasticity may be a contraindication any weightbearing restrictions seizure disorder that is not controlled by medication (if on medication, must not have had a seizure in the last 12 months) open skin lesions or vascular disorder of lower extremities not able to co-operate or be positioned adequately within the Lokomat as shown during the two Lokomat fitting/acclimatisation sessions
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  TBI Traumatic Brain Injury Age > 18 years Brain injured patients with a diagnosis of NHO around the hip and/ or knee for a period of greater than one year Patients who are able, or legal guardians who are willing, to provide informed consent after both oral and written information  Pregnancy Rheumatoid arthritis, ankylosing spondylitis, or femoral neck fractures Elevated serum alkaline phosphatase (SAP) levels and/or evidence of active bone remodelling in bone scan
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 16.0-65.0,  Osteochondral Lesion of Talus Degenerative Lesion of Articular Cartilage of Knee single osteochondral lesion in knee/ankle (2-4 sq cm)  multiple osteochondral lesions pre-existing injuries/arthropathies
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 50.0-100.0,  Peripheral Nerve Block Pain Age> 50 years Patients set to cemented Total knee arthroplasty in spinal block ASA 1-3  Patients who can not cooperate with the investigation Patients who have given written informed consent to participate in the study after having understood the contents of the protocol and limitations fully Patients who do not understand or speak Danish Patients receiving immunosuppressive therapy Patients receiving glucocorticoid daily Patients with a treatment-dependent diabetes mellitus Patients with known neuropathy in the lower limbs Allergy to those used in the study drugs Alcohol and / or drug abuse the investigator's opinion
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Osteoarthritis of Hip Osteoarthritis, Knee Planned primary unilateral THA or TKA Patients (male/female) ≥ 18 år Patients giving written informed consent and authority Patients receiving spinal anaesthesia  Patients with intolerance to trial medications Rejection of or contraindicated spinal anaesthesia Patients with rheumatoid arthritis Patients with Body Mass Index (BMI) ≥ 35 Patients that do not read or write Danish
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 16.0-40.0,  Primary Hypertrophic Osteoarthropathy diagnosed with primary hypertrophic osteoarthropathy clinically over 16 years old no other medication intake informed consent signed  below 16 years old active gastric ulcer inflammatory bowel disease New York Heart Association classification（NYHA） II to IV liver or renal failure allergic to nonsteroid anti-inflammatory drugs not willing to participate
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 1.0-6.0,  Caudal Block Patients aged 1-6 years, classified as American Society of Anesthesiologist (ASA) 1 and 11 who are undergoing herniotomy and whose parents or legal guardian has duly signed an informed consent form  Patients with hypersensitivity to any local anesthetics Children with Bleeding diathesis Presence of Infections at puncture sites Preexisting neurological disease Patients with diabetes mellitus Failure to consent by parents
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 1.083-40.0,  Recurrent Osteosarcoma Patients must have recurrent high-grade OS verified by histopathology review by MSKCC's Department of Pathology Patients must be in a ≥2nd complete remission as indicated by appropriate radiologic evaluations at the time of study entry Patients must be older than 1 year of age and less than or equal to 40 years of age Prior therapy: ≥3 weeks should have elapsed since last cytotoxic therapy, immunotherapy or radiation therapy. More than one week should have elapsed since major surgery Adequate hematopoietic function defined as Absolute neutrophil count ≥ 500/ul Absolute lymphocyte count ≥ 500/ul Platelet count ≥ 50,000/ul (transfusion independent) Adequate hepatic function as defined by Total bilirubin of ≤ 1.5 times upper limit of normal (exception is made for patients with Gilbert's syndrome who may be considered eligible if total bilirubin is ≤ 3 times upper limit of normal)  Patients with OS in first complete remission Presence of overt metastatic disease at any site Active life-threatening infection Pregnant women or women who are breast-feeding Inability to comply with protocol requirements
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Infection Immune Deficiency Hypogammaglobulinemia Septic Arthritis Mycoplasma Hominis Adult with decision making capacity afflicted with chronic mycoplasma hominis septic arthritis despite standard treatments
Patient description: A 10-year-old boy comes to the emergency department for evaluation of right knee pain. The child's guardians stated that he had been complaining of knee pain for the past 4 days and it had been getting progressively worse. There was no history of trauma. The day before the visit the boy developed a fever, and over the past day he has become increasingly lethargic. On physical examination blood pressure was 117/75 mm Hg, HR 138 bpm, temperature 38.1 C (100.5 F), respiration 28 bpm, oxygen saturation 97%. There was edema and tenderness of the right thigh and knee, as well as effusion and extremely limited range of motion. Sensation and motor tone were normal. Plain radiography and CT showed an osteolytic lesion.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Periprosthetic Joint Infection Septic Arthritis adult of 18 or more years written consent to participate in study suspicion of septic arthritis or periprosthetic joint infection joint aspirate minimum of 5 ml  is not able to understand the aim or purpose of this study empty joint aspirate