Patient description: The patient is a 60-year-old Spanish man presenting with shortness of breath about a day before. The symptoms began acutely and progressively worsened. He is a known case of COPD since 2 years ago. The spirometry revealed post-bronchodilator FEV1/FVC = 60% of predicted values. He smokes 20 cigarette per day. His past medical history is remarkable for BPH and he is using Flomax for that. His family history is positive for HTN in his brother. His medication includes Duo-Neb inhaled q4 hr PRN, Vit D3 1000 units per day and Flomax for his PBH. He is an obese man who is acutely ill but oriented and conscious. The vital signs are as bellow: BP: 135/80 RR: 25/min HR: 75 bpm BMI: 40 O2sat: 90%

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Asthma Pulmonary Disease, Chronic Obstructive Airway Disease (Asthma and COPD) 1. Participant is willing and able to give informed consent for participation in the study. 2. Male or Female, aged 18 years or above. 3. Participants diagnosed with Asthma or COPD with airflow limitation (FEV1% predicted < 80%) with no exacerbations for at least 4 weeks prior to study entry. 4. Participant has no clinical contraindication for CMR scan. 5. Able (in the Investigators opinion) and willing to comply with all study requirements. 6. Willing to allow his or her General Practitioner and consultant, if appropriate, to be notified of participation in the study. Healthy Volunteers 1. Participant is willing and able to give informed consent for participation in the study. 2. Male or Female, aged 18 years or above. 3. Healthy participant in good health with no past history of cardiovascular or respiratory disease. 4. Participant has no clinical contraindication for CMR scan. 5. Able (in the Investigators opinion) and willing to comply with all study requirements. 6. Willing to allow his or her General Practitioner and consultant, if appropriate, to be notified of participation in the study  Airway Disease (Asthma and COPD) The participant may not enter the study if ANY of the following apply: 1. Female participants who are pregnant, lactating or planning pregnancy during the course of the study. 2. Severe renal impairment eGFR < 30 ml/min. 3. Contraindication for undergoing CMR scan including permanent pacemaker and surgical procedure within last 6 weeks. 4. Unable to understand / read English 5. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study. Healthy Volunteers The participant may not enter the study if ANY of the following apply: 1. Female participants who are pregnant, lactating or planning pregnancy during the course of the study. 2. Severe renal impairment eGFR < 30 ml/min. 3. Contraindication for undergoing CMR scan including permanent pacemaker and surgical procedure within last 6 weeks. 4. Unable to understand / read English 5. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study