semaj83/ctmatch_classification huggingface dataset:
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 20.0-39.0,  Pregnancy Related Sleep Disordered Breathing Obesity Pregnant women: 1. Between the ages of 20-39 yrs, 2. At 32-34 weeks gestation, 3. Who have a BMI of ≥30 to ≤40 kg/m2, 4. Who have a singleton pregnancy, and 5. Who have a normal glucose tolerance test on entrance to the study  Pregnant Women: 1. Who have a diagnosis of diabetes (GDM, type 1 or type 2), 2. Who are using beta blockers/glucocorticoids. 3. Who have other children who are ≤2 yrs old (due to risk of disrupted sleep), 4. With diagnosed sleep disorders (e.g. OSA, insomnia, restless leg syndrome), 5. Who work night or rotating shifts, 6. Who report use of sleep medications will be excluded, 7. With diagnosed pulmonary or cardiovascular disease 8. Who do not speak English
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Obesity Obstructive Sleep Apnea Syndrome Patients over 18 years of age male or female obesity defined by a body mass index (BMI = weight in kg / height in m²) ≥ 30 free from acute or chronic painful pathology free from any chronic analgesic treatment free from any psychotropic treatment by benzodiazepine and / or tricyclic antidepressant presence of obstructive sleep apnea syndrome (with apnea-hypopnea index (IAH) 10 per hour of sleep) among 60 patients absence of obstructive sleep apnea syndrome (IAH <10 per hour of sleep) among 60 patients person who signed the information and consent form patients who have been screened for sleep apnea syndrome by Somnochek® negative (AHI <10 / h) in the last 6 months, provided that their weight is the same or lower at the time of  difficulties in understanding and speaking French an alcohol abuse or dependence (DSM-IV) an abuse or dependence on illicit drugs (DSM-IV) an acute or chronic inflammatory pathology a neuro-muscular pathology clinical signs of right heart failure an analgesic treatment treatment with benzodiazepines and / or tricyclic antidepressants, a β-blocking treatment Central sleep apnea person who is absent from another study or who has received more than 4500 euros in the year following his participation in clinical studies
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 30.0-64.0,  Metabolic Syndrome Obesity Central Obesity 3,720 baseline participants (mean±SD age(y) of 48.3±9.4, 45.3% men, and 59.1% African-American), 2. Genetic data were available on 1,024 African-American participants. 3. Incomplete covariate data reduced the sample to n=769, while additional exclusions lead to a sample size ranging between 574 and 598 participants, with 539 having complete data on all baseline and follow-up outcome measures (cross-sectional part of the analysis). 4. In the longitudinal analysis, metabolic disturbance-free at baseline participants were selected for each outcome. Sample sizes ranged from n=246 (central obesity-free) to n=466 (hyperglycemia-free). 5. There were n=294 MetS-free individuals at baseline  Whites in since they did not have any genetic data collected. 2. All African-Americans in without genetic data collected. 3. All African-Americans in with genetic data collected, who had incomplete data on key outcome variables and/or basic covariates of interest
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Infant,Premature Feeding; Difficult, Newborn Infant Born preterm (<37 weeks gestational age) at time of birth Corrected gestational age is <37 weeks per the modified Dubowitz score on date of enrollment Diagnosed with feeding difficulties Patient in the mother-baby unit at KATH Clinically indicated to start cup feeding (including an infant who has a nasogastric tube and is cup feeding or indicated to start cup feeding) Has an anticipated hospital stay that is at least 48 hours Caregiver At least 18 years of age One of the following biologic family members of the infant (Mother, Grandmother, Aunt) Self-identifies as the primary feeder of the infant  Infant Congenital anomaly except for minor anomalies (e.g. an extra digit or ear tag is okay) Other condition or situation that makes infant unlikely to be able to comply with study procedures. Examples the infant anticipated to not be in hospital long enough, infant has a suspected intestinal obstruction, or necrotizing enterocolitis No mother, grandmother, or aunt caregiver available to participate in study Enrolled in another study at KATH that would interfere with his/her ability to participate in this study
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Coronary Heart Disease years or older Have no CHD at enrollment At high risk of CHD with at least two of the following risk factors current smoking: current smokers are defined as individuals who smoked regularly during the last 12 months central obesity: for Chinese, central obesity is defined as waist circumstance above 90cm for male and 80cm for female, or with BMI above 30kg/m² raised BP (systolic BP [SBP] ≥ 130 mmHg or diastolic BP [DBP] ≥85 mmHg or under antihypertensive treatment) raised fasting BG (FBG) (100mg/dL [5.6mmol/L]) or under treatment with insulin or oral hypoglycemic agents elevated TG (150mg/dL [1.7mmol/L]) elevated TC (≥ 240 mg/dL [5.18 mmol/L]) raised LDL-C (≥ 160 mg/dL [4.15 mmol/L])  Impaired bilateral hearing Impaired mental status (according to their medical record)
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  IBS - Irritable Bowel Syndrome Verified IBS according to Rom IV criteria  Serious mental or somatic disease Abuse Inability to understand he Swedish language Already on a diet (e.g. vegan, gluten-free)
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Menstrual Cycle Abnormal PCOS Overweight Obesity Aged 18-45 years At least 2y post-menarche BMI >18.5kg/m2 Good visibility of the ovaries on ultrasound Either Regular menstrual cycles (21-35 days) Irregular menstrual cycles (>35 days); or Previous diagnosis of PCOS from a primary care provider  Weight >300lbs Currently pregnant or breast feeding History of ovarian surgery Use of medications or supplements known or suspected to interfere with reproductive function and/or glucose and lipid metabolism in the past 3 months Evidence of reproductive aging as assessed by the principal of STRAW+10 stages
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 18.0-40.0,  Maternal Vitamin D Status maternal age of 18-40 years gestational age of 12 weeks or less singleton pregnancies mothers supposed to have normal pregnancy and not having preexisting diseases like hypertension, or cardiac, renal, hepatic, autoimmune , rheumatoid arthritis and digestive disease, or endocrinological disorders including diabetes (type 1 or type 2 diabetes), parathyroid disorders, and thyroid disorder not receiving dietary supplements including vitamin D (>600 IU/d), or omega-3 within the past 3 months before the intervention not taking medications that could potentially influence vitamin D metabolism willingness to participate in the study  Participants who do not meet the those who diagnosed to have fasting blood sugar (FBS)>92 at first blood sampling and/or blood pressure > 140/90 mmHg at the first visit using extra vitamin D3 supplement and/or omega-3 and/or other medications that could potentially influence vitamin D metabolism fetal anomaly poor adherence to the study protocol unwillingness to continue the intervention
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 20.0-75.0,  Obesity Patients with obesity disease and inadequately controlled body weight with diet and/or exercise BMI ≥ 25 kg/m^2 combined with at least two obesity-related comorbidities, or BMI ≥ 35 kg/m^2 at least one obesity-related comorbidity Patients with FPG ≥ 110 mg/dL and/or 5.6% ≤ HbA1c ≤ 10.0%, or T2DM with HbA1c ≤ 10.0% Waist circumference at umbilical level ≥ 85 cm for male, ≥ 90 cm for female Visceral fat area ≥ 100 cm^2 Agreement to comply with the study-required life-style intervention and treatment during the full duration of the study  Pregnancy or lactating women Use of pharmacologically active weight-loss medications Bariatric surgery Ketoacidosis, lactic acidosis, hyperosmolar coma Symptomatic genital ingection or urinary tract infection in the 4 weeks prior to screening Gastro-intestinal (GI) disorders associated with chronic diarrhea Congestive heart failure, New York Heart Association (NYHA) class III or IV
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Healthy Male or female participants between 18 and 45 years of age, inclusive Have a body weight ≥45 kg (Female) or ≥50 kg (Male), and a body mass index (BMI) between 19 and 26 kg/m^2, inclusive Participants are in good health without any significant clinical abnormalities as determined by the investigator on the basis of medical history, physical examination (including vital signs) and baseline test results (hematology, blood chemistry, blood coagulation, urinalysis and 12-lead electrocardiogram (ECG)) Participants and the spouses who are willing to use a medically accepted method of contraception (e.g. placement of an intrauterine device or intrauterine system, contraceptive drugs, using condom) during the study period and for one month thereafter Participants who are willing to sign and date the approved informed consent form (ICF)  Female subjects of childbearing potential have positive serum pregnancy test results or are lactating at screening Subjects who have their daily cigarette smoking to five or more for 3 months prior to screening History of severe or multiple drug allergies History of alcohol abuse in the past 3 months prior to screening (Alcohol consumption >14 units per week: 1 unit = 10 mL alcohol, 250mL of 4 degrees beer, 25 mL of 40 degrees spirit or 75 mL of 13 degrees wine) History of any drug abuse, or have a positive urine drug screen result at screening, or history of any psychotropic medication abuse within 5 years prior to screening Previous exposure to any other Investigational Medicinal Product (IMP) or participation in any clinical trial within 3 months prior to screening Donation or loss of blood over 450 mL within 3 months prior to screening Use of any prescription, over-the-counter, herbs, or medications which can change the pH values of gastrointestinal tracts (e.g. antacids, H2 receptor inhibitors and/or proton-pump inhibitors) within 28 days prior to screening Receiving caffeine-containing food or drinks, or alcohol-containing products within 24 hours prior to study drug administration Smoking and use of any nicotine-containing products within 24 hours prior to study drug administration
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 40.0-75.0,  Pharmacokinetics Body Mass Index (BMI) of 18 kg/m2 to 32 kg/m2 Body weight of at least 50 kg at screening Good health as determined by evaluations Negative serum pregnancy test Subjects who are naturally postmenopausal for at least 12 consecutive months with a follicle-stimulating hormone level at Screening of ≥40 mIU/mL Subjects who are peri-menopausal and experiencing at least one of specified symptoms of menopause (eg, hot flashes, mood swings, night sweats, and others) Negative urine test for drugs of abuse Negative urine test for HIV antibody, HBsAG, and HCV at Screening Women of child-bearing potential must agree to consistently practice contraception throughout the duration of the study and continue to do so for 1 year after receiving study drug by one of the following methods: abstinence, condom, diaphragm or cervical cap with spermicide, intrauterine device or male partner had previously undergone a vasectomy as declared in medical history  Recent history (6 months) or current evidence of any clinically significant (uncontrolled) disorder including hepatic, renal, cardiovascular, psychological, pulmonary, metabolic, endocrine, neurologic, infectious, gastrointestinal, hematologic or oncologic disease, or other medical conditions that may interfere with the subject completing the study Lab test results outside the normal range at Screening or Day 1 considered clinically significant by the Investigator Use of hormonal replacement therapy within 6 months prior to randomization an/or current use of oral contraceptive pill or patch as contraceptive method throughout the study Concomitant medication that can affect bleeding Recent history (6 months) or presence of an abnormal ECG that, in the opinion of the Investigator, is clinically significant Subjects with QTcF interval duration >470 milliseconds History of alcoholism or drug addiction within 1 year prior to Day 1 History of allergy or a known sensitivity to product components of fulvestrant Test and Reference formulations Creatinine clearance <60 mL/minute based on the Cockcroft-Gault equation Blood donation of 500 mL or more or a significant loss of blood within 56 days prior to Day 1
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Aged Postoperative Period Intensive Care Units Mechanical Ventilation Complication Sleep Disorders Dexmedetomidine aged 18 years or older admitted to the ICU after surgery with an expected duration of mechanical ventilation of more than 12 hours (admitted before 21:00 on the day of surgery and extubated after 06:00 on the first day after surgery)  refused to participate aged less than 18 years pregnant preoperative history of schizophrenia, epilepsy, parkinsonism, or myasthenia gravis inability to communicate in the preoperative period (coma, profound dementia, or language barrier) brain injury or neurosurgery known preoperative left ventricular ejection fraction less than 30%, sick sinus syndrome, severe sinus bradycardia (<50 beats per min), or second degree or greater atrioventricular block without pacemaker, systolic blood pressure less than 90 mmHg despite continuous infusions of vasopressors before the start of study drugs infusion serious hepatic dysfunction (Child-Pugh class C) serious renal dysfunction (undergoing dialysis before surgery) less likelihood to survive for more than 24 hours
Patient description: The patient is a 32-year-old obese woman who came to the clinic with weight concerns. She is 165 cm tall and her weight is 113 kg. She is complaining of sleep apnea, PCO and dissatisfaction with her body shape. She is a high-school teacher married for 5 years. She doesn't use any contraceptive methods for the past 4 months and she had no prior pregnancies. She doesn't smoke or use any drugs. She likes to try diets and exercise to lose weight. She completed the four square step test in 14 seconds. Her BP: 130/80, HR: 195/min and her BMI is: 41.54. Her labs: FBS: 98 mg/dl TG: 150 mg/dl Cholesterol: 180 mg/dl LDL: 90 mg/dl HDL: 35 mg/dl Her cardiac assessment is normal. Her joints and ROM are within normal.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Sleep Disordered Breathing Hypoxia Respiration; Sleep Disorder Chemoreceptor Apnea normotensive forced expiratory volume in 1s : forced vital capacity ratio > 0.75 no medical history of cardiovascular and respiratory disease not taking medications other than oral contraceptives free from sleep apnea body mass index less than 30 kg/m2  history of hypertension known impaired renal function liver disease heart failure myocardial infarction coronary artery disease smoked within the past year apnea hypopnea index > 5 events per hour