Patient description: A 67-year-old healthy woman came to the clinic to have her flu shot in early October. She works at a rehab center and has no underlying disease. It is her first vaccination this year. she is menopausal and has 4 children. She does not some. She takes daily multivitamins and anti-hypertensive drugs. She exercises regularly for 30 minutes a day at least 5 days a week. She has no allergies to any food or drugs.

Clinical trial eligibility criteria: eligible ages (years): 5.0-999.0,  Allergies Allergic Rhinitis Asthma Pediatric and adult timothy grass and Dermatophagoides farinae-sensitive subjects with allergic rhinoconjunctivitis with or without asthma perennially or during grass pollen season. 2. Subjects must be 5 years of age or older. 3. Sensitivity to the relevant allergen will be documented by a positive skin prick test result (see Appendix E for details). 4. All female subjects of child-bearing potential will be required to provide a urine sample for pregnancy testing that must be negative one week before being allowed to participate in the study. 5. Subjects must be planning to remain in the study area during the trial. 6. Subjects and/or their parents must be trained on the proper use of the Epi-Pen to be allowed to enroll in the study. 7. Subjects and/or their parents must be mentally and physically capable of self-administering oral drug  No absolute contraindications to allergen skin testing and/or sublingual immunotherapy are known. However, the risk of serious systemic anaphylactic reactions to pollen or any potent allergenic extract suggests a number of preexisting conditions that should be considered relative contraindications. Among those conditions are acute infections, autoimmune disease, severe cardiac disease, and treatment with beta-adrenergic antagonistic drugs (beta-blockers). 1. Subjects having a history of unexplained anaphylaxis within 2 years or a history of multiple (≥2) episodes of anaphylaxis in the past year, frequent allergic or non-allergic urticaria, or history consistent with poorly controlled persistent asthma. Anaphylaxis must be medically diagnosed. 2. Subjects with unstable angina, significant arrhythmia, uncontrolled hypertension, chronic sinusitis, or other chronic or immunological diseases that in the mind of the investigator might interfere with the evaluation or administration of the test drug or pose additional risk to the subject e.g. gastrointestinal or gastroesophageal disease, chronic infections, scleroderma, hepatic and gallbladder disease, chronic non-allergic pulmonary disease. 3. Subject with an FEV1 or PEF less than 80% predicted (moderate persistent asthma) with or without controller medication. 4. Subjects who have received an experimental drug in the last 30 days prior to admission into this study or who plan to use an experimental drug during the study. 5. Subjects who have received timothy grass or dust mite allergen immunotherapy within 3 years prior to admission in this study. 6. Subjects who are current users of oral, intramuscular, or intravenous corticosteroids, tricyclic antidepressants, or are taking a beta-blocker (oral or topical). 7. Subjects routinely using medication that could induce adverse gastrointestinal reactions during the study. 8. Subjects refusing to sign the EpiPen Training Form (see Appendix F). 9. Pregnant or breast feeding females. 10. Subjects who have any symptoms at dose levels 1 or 2 at the Preliminary Dosing Visit (see, below). 11. Subjects with significant pet allergies who have significant exposure at home or at work