semaj83/ctmatch_classification huggingface dataset:
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 3.0-18.0,  Encephalitis, Tick-Borne Participated in Baxter study 209 and They and/or their parents / legal guardians understand the nature of the study and agree to its provisions Written informed consent is available from the parents / legal guardians according to national law Written informed assent is available from the child/adolescent according to age and capacity of understanding They received the third vaccination with FSME-IMMUN 0.25 ml during the course of Baxter study 209 Blood was drawn after their third vaccination during the course of Baxter study 209 They showed an ELISA concentration > 126 VIE U/ml and / or a NT titer >=10 after the third vaccination in Baxter study 209 They or their parents / legal guardians agree to keep a Subject Diary  Received any TBE vaccination since their third vaccination with FSME-IMMUN 0.25 ml Have a history of infection with or vaccination against other flaviviruses (Dengue fever, yellow fever and / or Japanese B-encephalitis virus) since their third vaccination with FSME-IMMUN 0.25 ml Are known to be HIV positive (a special HIV test is not required for the purpose of the study) since their third vaccination with FSME-IMMUN 0.25 ml Received a blood transfusion or immunoglobulins within 30 days of the first and second blood draw (as applicable) Have a known or suspected problem with drug or alcohol abuse (> 4 liters wine / week or equivalent level of other alcoholic beverages) Have participated in another Baxter vaccine study within the last six months (with the exception of follow-up studies) Subjects will not be eligible for booster vaccination if they Do not meet the / Are not clinically healthy, (i.e. the physician would have reservations vaccinating with a TBE vaccine outside the scope of a clinical trial) Suffer from a disease (e.g. autoimmune disease) or are undergoing a form of treatment (e.g. systemic corticosteroids) that can be expected to influence immunological functions
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 17.0-66.0,  Encephalitis, Tick-borne Male and female subjects who received 2 vaccinations with FSME-IMMUN 0.5 ml during Study 225 understand the nature of the study, agree to its provisions and provide written informed consent are clinically healthy (i.e. the physician would have no reservation vaccinating with FSME-IMMUN 0.5 ml outside the scope of the clinical trial) have a negative pregnancy test result at the first medical examination (if female and capable of bearing children) agree to employ adequate birth control measures for the duration of the study (if female and capable of bearing children) agree to keep a Subject Diary  Subjects who have already been administered a third TBE vaccination elsewhere since receiving two vaccinations in Study 225 have a history of infection with, or vaccination against, other flaviviruses since participation in Study 225 (e.g. yellow fever, dengue fever, japanese B encephalitis) have had an allergic reaction to one of the components of the vaccine since participation in Study 225 suffer from a disease (e.g. autoimmune disease, immunodeficiency) or are undergoing a form of treatment (e.g., systemic corticosteroids) that can be expected to influence immunological functions have a known or suspected problem with drug or alcohol abuse (>4 liters wine/week or equivalent doses of other alcoholic beverages) have donated blood or plasma within 30 days of study entry have received a blood transfusion or immunoglobulins within 30 days of study entry are known to be HIV positive (an HIV test is not required specifically for this study) are simultaneously participating in another clinical trial including administration of an investigational product
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 7.0-11.0,  Encephalitis, Tick-borne Male and female children who participated in Study 146A if they and/or their parents/legal guardians understand the nature of the study and agree to its provisions written informed consent is available from the child (according to age and capacity of understanding) and the parents/legal guardians they received the complete 3-immunization primary vaccination series with either 0.5 ml or 0.25 ml TicoVac in Study 146A they received FSME-IMMUN 0.25 ml Junior for their first booster vaccination approximately 3 to 4 years after their third vaccination in Study IMAG-146A  Subjects who received any further TBE vaccination since their first TBE booster vaccination Subjects with a history of infection with, or vaccination against, other flaviviruses (e.g. dengue fever, yellow fever and/or japanese B encephalitis virus) since their third vaccination in Study 146A Subjects who have suffered from a disease (e.g. autoimmune disease) or have undergone a form of treatment (e.g. systemic corticosteroids) that can be expected to influence immunological functions within 30 days before and after their first TBE booster vaccination Subjects who have been known to be HIV positive (a special HIV test is not required for the purpose of the study) since their third vaccination in Study 146A Subjects who have received a blood transfusion or immunoglobulins within 30 days of study entry
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Relapsing Fever, Tick-Borne Jarisch Herxheimer Reaction suspected exposure to tick-borne relapsing fever after returning from field exercise in a tick-borne relapsing fever infected area having a tick bite or staying in field in close proximity to a subject with tick bite sign  known sensitivity to tetracycline or doxycycline febrile illness on recruitment
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 1.0-10.0,  Encephalitis, Tick-Borne Healthy male and female children, 1 to 10 years of age  Subjects with documented evidence of TBE Subjects, who have been previously vaccinated against TBE
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 13.0-999.0,  HIV Infections Coenrollment in the SMART study Parent or guardian willing to provide informed consent, if applicable
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  HIV Infections Coenrollment in the SMART study  Unable to comply with all study requirements
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 0.167-4.917,  Severe Pneumonia Age: 2 to 59 months Sex: Both boys and girls Severe pneumonia according to WHO (Severe pneumonia is defined as cough or difficult breathing with lower chest wall in drawing with or without fast breathing which is defined as the respiratory rate ≥ 50 breaths per minute for children aged 2-11 months and ≥ 40 breaths per minute for children aged 12-59 months) Attend the Radda Clinic and ICHSH between 8:00 am to 4:00 pm (Sunday through Saturday) Written informed consent by respective parents/guardians  Very severe and non-severe pneumonia Nosocomial pneumonia History of taking antibiotics for pneumonia within 48 hour prior to enrollment Chronic illnesses like tuberculosis, cystic fibrosis Congenital deformities/anomalies e.g. Down's Syndrome, congenital heart disease Immunodeficiency Trauma/burn Bronchiolitis Bronchial asthma Lives far away from the Radda Clinic and ICHSH (outside 5 km radius from the respective study site)
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 16.0-999.0,  Encephalitis, Tick-Borne Male and female subjects will be eligible for participation in this study if they Understand the nature of the study, agree to its provisions and provide written informed consent (assent if the subjects is under 18 years of age) Provide the written informed consent of their parents / legal guardian (if the subject is under 18 years of age) Are aged >= 16 years (from the 16th birthday) at screening Are clinically healthy, (i.e. the physician would have no reservations vaccinating with FSME-IMMUN 0.5 ml outside the scope of a clinical trial) Have a negative pregnancy test result at the first medical examination (if female and capable of bearing children) Agree to employ adequate birth control measures for the duration of the study (if female and capable of bearing children) Agree to keep a Subject Diary  Subjects will be excluded from participation in this study if they Have a history of any previous tick-borne encephalitis (TBE) vaccination Have a history of TBE infection Have a history of infection with or vaccination against other flaviviruses (e.g. dengue fever, yellow fever, Japanese B-encephalitis) Have a history of allergic reactions, in particular to one of the components of the vaccine Suffer from a disease (e.g. autoimmune disease) or are undergoing a form of treatment (e.g. systemic corticosteroids) that can be expected to influence immunological functions Have a known or suspected problem with drug or alcohol abuse (> 4 liters wine / week or equivalent level of other alcoholic beverages) Have donated blood or plasma within 30 days of study entry Have received a blood transfusion or immunoglobulins within 30 days of study entry Are known to be HIV positive (an HIV test is not required specifically for the purpose of this study)
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 18.0-55.0,  Typhoid Fever Healthy Males or Females aged 18 to 55 years, inclusive Capable of understanding and complying with the protocol requirements and be available for the duration of the protocol  History of malignancy, immunocompromised conditions or currently receiving immunosuppressive treatment including systemic steroids History of Typhoid Fever infection, vaccination against typhoid fever or participation in a Clinical Trial using S.typhi organism at any time History of travel to a typhoid endemic region within the last 5 years or history of raising a child from an endemic area. Endemic regions are South and East Asia, the Indian Subcontinent, Africa and Central and South America including Mexico History of persistent diarrhea, blood in stool, peptic ulcer disease, or inflammatory bowel disease Allergies or sensitivities to antibiotics, notably quinolones, penicillins, sulfonamides, cefalosporins and chloramphenicol, and components of the buffer solution, notably aspartame People who are commercial food handlers, day care workers, or health care workers involved in direct patient care. Also people with young children under 2 years of age at home or household contacts who are immunocompromised, pregnant or breast-feeding
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Encephalitis, Tick-Borne Subjects who participated in Study 223 will be eligible for participation in this study if they understand the nature of the study, agree to its provisions and provide written informed consent they received the first booster vaccination with FSME-IMMUN 0.5ml during the course of study 223 blood was drawn after their first booster vaccination in Study 223  Subjects will be excluded from participation in this study if they received any TBE vaccination since their first booster vaccination with FSME-IMMUN 0.5ml have a history of infection with or vaccination against other flaviviruses (e.g. dengue fever, yellow fever, Japanese B-encephalitis) since their first booster vaccination with FSME-IMMUN 0.5ml are known to be HIV positive (a special HIV test is not required for the purpose of the study) since their first booster vaccination with FSME-IMMUN 0.5ml have a known or suspected problem with drug or alcohol abuse (> 4 liters wine / week or equivalent level of other alcoholic beverages) Subjects will not be eligible for booster vaccination if they are not clinically healthy, (i. e. the physician would have reservations vaccinating with FSME-IMMUN 0.5ml outside the scope of a clinical trial) suffer from a disease (e.g. autoimmune disease) or are undergoing a form of treatment (e.g. systemic corticosteroids) that can be expected to influence immunological functions are females of childbearing potential and are pregnant or breastfeeding before the booster vaccination (positive pregnancy test result at the medical examination before the booster vaccination) have shown an allergic reaction to one of the components of the vaccine since their first booster vaccination in Study 223
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 0.75-3.0,  Cryptosporidiosis Male and female children aged 9-36 months at the time of enrollment Presence of acute or persistent diarrhea (diarrhea defined as 3 or more loose stool in the previous 24 hours AND not considered normal for that child if the child is exclusively breast fed OR any number of bloody stools in the previous 24 hours; less than or equal to 14 days duration for acute diarrhea; >14 days duration for persistent diarrhea) Child's parent/guardian speaks English or Luganda Parent/guardian provides full and free informed consent for child to participate in study  Unknown age Known cardiac, CNS, metabolic or endocrine disorders Moribund children Children with recent history of choking or sudden onset of symptoms with suspected foreign body inhalation
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 0.5-5.0,  Pneumonia Malaria Age between 6 months and 5 years Present with history of fever or reported fever Present with cough or difficult breathing  Age below 6 months and above 5 years Presence of signs and symptoms of severe illness
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Dengue Fever Dengue Hemorrhagic Fever Dengue Virus Healthy, as determined by medical history, clinical examination, and biological safety parameters Aged 18 to 45 years on the day of inclusion Provision of informed consent signed by the subject or another legally acceptable representative For a woman of child-bearing potential, use of an effective method of contraception or abstinence for at least 4 weeks prior to the first vaccination, and until at least 4 weeks after the last study vaccination Able to attend all scheduled visits and to comply with all trial procedures  Personal or family history of thymic pathology (thymoma), thymectomy, or myasthenia For a woman of child-bearing potential, known or suspected pregnancy or positive serum/urine pregnancy test Breast-feeding woman Participation in another clinical trial investigating a vaccine, drug, medical device, or a medical procedure in the 4 weeks preceding the first trial vaccination Planned participation in another clinical trial during the present trial period Known or suspected congenital or acquired immunodeficiency, immunosuppressive therapy such as anti-cancer chemotherapy or radiation therapy within the preceding 6 months, or long-term (at least 2 weeks within the previous 3 months) systemic corticosteroids therapy (at a dose of at least 10 mg). Topical steroids are allowed Known systemic hypersensitivity to any of the vaccine components or history of a life-threatening reaction to the trial vaccine or to a vaccine containing any of the same substances Chronic illness at a stage that could interfere with trial conduct or completion, in the opinion of the investigator Current or past alcohol abuse or drug addiction that may interfere with the subject's ability to comply with trial procedures Receipt of blood or blood-derived products in the past 3 months, that might interfere with the assessment of immune response
Patient description: An 8-year-old male presents in March to the ER with fever up to 39 C, dyspnea and cough for 2 days. He has just returned from a 5 day vacation in Colorado. Parents report that prior to the onset of fever and cough, he had loose stools. He denies upper respiratory tract symptoms. On examination he is in respiratory distress and has bronchial respiratory sounds on the left. A chest x-ray shows bilateral lung infiltrates.

Clinical trial eligibility criteria: eligible ages (years): 35.0-72.0,  Irritable Bowel Syndrome Small Intestinal Bacterial Overgrowth Men and women age 32-75 years Rome III for diarrhea-predominant IBS Symptom onset after an apparent episode of acute gastroenteritis Symptoms of > 3 months duration Normal endoscopic appearance of the colonic mucosa Negative markers for celiac disease and inflammatory bowel disease Normal thyroid function and serum calcium levels Must have served in the military or reserves during the time of Operation Desert Storm (August 1990 to May 1991)  Clinically significant cardiac, pulmonary, hepatic or renal dysfunction History of/or presence of systemic malignancy Current evidence of any gastrointestinal disorder such as celiac disease or inflammatory bowel disease (i.e. Crohns disease or ulcerative colitis) Current effects of drug or alcohol abuse Investigator perception of patients inability to comply with study protocol Unstable psychiatric disease Recent change in gastrointestinal medications Subjects with a positive pregnancy test Subject is currently participating in another research protocol that could interfere or influence the outcome measures of the present study