semaj83/ctmatch_classification huggingface dataset:
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 10.0-18.0,  Multiple Sclerosis Body weight >/= 25 kg Children and adolescents must have received all childhood required vaccinations Female participants of childbearing potential must agree to either remain completely abstinent or to use reliable means of contraception Diagnosis of relapsing-remitting multiple sclerosis (RRMS) Expanded Disability Status Scale (EDSS) at screening: 0-5.5, inclusive Neurologic stability for >/= 30 days prior to screening, and between screening and baseline Participants naive to prior disease-modifying therapy (DMT) Participants who have had at least 6 contiguous months of DMT within the past 1 year must have evidence of disease activity occurring after the full 6-month course of treatment, that is, at least one relapse or >/= 1 Gd-enhancing lesion(s) on a T1-weighted brain MRI  Known presence or suspicion of other neurologic disorders that may mimic MS, including, but not limited to, acute disseminated encephalomyelitis, neuromyelitis optica or neuromyelitis optica spectrum disorders and any neurologic, somatic, or metabolic condition that could interfere with brain function or normal cognitive or neurological development Patients that are aquaporin 4 positive and myelin oligodendrocyte glycoprotein (MOG) antibody positive are not eligible to participate in the study In case of an ADEM-like appearance of the first MS attack, a second attack with clear MS-like features is required Infection requiring hospitalization or treatment with IV anti-infective agents History or known presence of recurrent or chronic infection (e.g., HIV, syphilis, tuberculosis) Receipt of a live or live-attenuated vaccine within 6 weeks prior to treatment allocation History or laboratory evidence of coagulation disorders Peripheral venous access that precludes IV administration and venous blood sampling Inability to complete a magnetic resonance imaging (MRI) scan History of cancer, including solid tumors, hematologic malignancies, and carcinoma in situ
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Peripheral Nerve Disease Peripheral Nerve Injury Lower Limb Poliomyelitis Cerebral Palsy Multiple Sclerosis patients at our Prosthetics and Orthotics Outpatient Clinic having an ankle-foot orthosis for at least 1 year  insufficient cognitive ability to fill in the ABC Scale
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Stroke Diagnosis of ischemic stroke in the right middle cerebral artery or right intra-cerebral hemorrhagic stroke, confirmed by brain CT and / or brain MRI; 2. Diagnosis of LHSN with a specific test (asymmetry score on Bells cancellation test > 3]); 3. Intra-hospital rehabilitation setting (ordinary hospitalization or DH) or outpatient setting; 4. Age between 18 and 80 years; 5. Time between stroke onset and study recruitment three weeks to three months; 6. Availability to provide informed consent to participation  Clinical instability at recruitment (for example, fever, acute internist conditions, etc.); 2. History of epilepsy and / or occurrence in the acute phase of at least one seizure crisis 3. Presence of intracranial metallic implants; 4. Presence of devices, which could be altered by r-TMS, such as pacemakers, ventricular-peritoneal derivations, Baclofen pump; 5. Absence of a bone operculum following a neurosurgical operation of decompressive craniotomy; 6. Presence of behavioral disturbances with inversion of the sleep-wake rhythm 7. Mono or bilateral occipital lesions documented on CT and / or history of cortical blindness or visual agnosia; 8. Concomitant psychiatric disorders and / or history of substance abuse; 9. State of pregnancy 10. Inability to execute the following simple order: "Take the pen instead of the key and put it on the sheet" 11. Severe acoustic deficit not corrected by the use of a hearing aid 12. Severe reduction of the visus despite the use of eyeglasses 13. Positive anamnesis of previous cognitive decline
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Multiple Sclerosis Diagnosis of MS according to the McDonald 2010 and cranial MRI scan demonstrating white matter lesions attributable to MS within 5 years before prior to signing the informed consent form (ICF) Age > 18 years Written informed consent to study participation  Medical, psychiatric, cognitive, or other conditions that, in the Investigator's opinion, compromise the patient's ability to understand the patient information, to give informed consent, or to complete the study Any progressive form of MS Any condition that serves as a contraindication for alemtuzumab treatment Any disability acquired from trauma or another illness that could interfere with the evaluation of disability due to MS Major systemic disease or other illness that would, in the opinion of the Investigator, compromise patient safety or interfere with the interpretation of study results, e.g., current peptic ulcer disease or other conditions that may predispose to hemorrhage Significant autoimmune disease including but not limited to immune cytopenias, rheumatoid arthritis, systemic lupus erythematosus, other connective tissue disorders, vasculitis, inflammatory bowel disease, severe psoriasis Inability to undergo MRI with gadolinium administration
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 40.0-70.0,  Multiple System Atrophy, Cerebellar Variant (Disorder) Patients who meet the clinical for probable multiple system atrophy with cerebellar features (MDS second consensus statement on the diagnosis of multiple system atrophy) Patients aged between 40 and 70 Patients who do not have rigidity and bradykinesia Patients who have given voluntary consent after understanding the content of the clinical trial  Patients with a serious cognitive disorder, behavioral disorder, or mental illness Patients have history of seizure, stroke, encephalitis, other degenerative neurological disease Patients with a serious medical disease Patients who concomitantly suffer from severe renal impairment, convulsions, stomach ulcers, moderate or more severe liver disease Patients with un-controlled high blood pressure or diabetes Patients who have taken another investigational products within 4 weeks prior to being enrolled in this clinical trial, or patients who are pregnant or breastfeeding
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Diagnosis of TIA MRI Patients with probable TIA with Regression of symptoms within 24 hours (unilateral motor or sensory disorders affecting the face and / or limbs , language disorder, blindness of an eye or amputation of a visual field) Patients with possible AIT with 2 of these symptoms associated: fear of heights, diplopia, dysarthria, disorders of swallowing, loss of balance, isolated sensory symptoms affecting only part of a limb or hemiface Patient who have had a brain MRI Patient over 18 year-old Patient who give their non opposition to participate at the study
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 21.0-80.0,  Stroke, Acute Hemiparesis confined to one side, (CMSA Stage 2 or 3 out of 7) 2. Absence of a brainstem and/or cerebellar lesion 3. Absence of severe concurrent medical problems (e.g. cardiorespiratory impairment, changes in management of hypertension) contraindicating comprehensive in-patient rehabilitation 4. Absence of any acute or chronic painful condition (including hypersensitivity) in the upper extremities or spine 5. Absence of severe aphasia (NIHSS #9, < 2) 6. Absence of profound extinction and inattention (NIHSS #11, < 2) 7. Ability to perform a 3-step motor command with the unaffected arm 8. Capacity to provide informed consent 9. 21 to 80 years old
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Catheter-Related Infections Catheter Related Complication Indication for intravenous medicine or fluids included in the following Blood products, isotonic saline or glucose-solutions (including glucose-insulin-potassium-solutions) Antibiotics (penicillins, cephalosporins, carbapenems or fluoroquinolones) Chemotherapy registered for use in a peripheral vein catheter Expected indication for intravenous access in 5 to 28 days Informed consent  Infection or burns at both upper extremities (Involving the area of puncture site) Pregnancy (Confirmed by positive urine human gonadotropin (hCG) or plasma-hCG) A central venous catheter already in place (Self-explanatory) Earlier randomized to the study (Self-explanatory)
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 20.0-45.0,  Multiple Sclerosis Sexual Dysfunction MS adolescent patients meeting the McDonald's criteria; 60 male cases and 60 female cases recruited from Mansoura University Hospitals  The Active relapse or relapse during 30 day prior to survey due to significant changes in all life activities during this period including sexuality EDSS score equal or higher than 6.5 Current pregnancy in female patients Form of the disease other than RRMS Patients with any sort of cognitive impairment preventing them from understanding Questionnaire Poorly controlled concomitant diseases were excluded Patients with past history of any sexual problems prior to the first MS attack UN married Patients
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Simvastatin Multiple Sclerosis Patients must have a confirmed diagnosis of multiple sclerosis according to revised Mc Donald 2017 and have relapsing remitting multiple scelerosis type. 2. EDSS up to 4. 3. Males and Females aged 18 to 65 4. pregnancy test within 7 days prior to being registered/randomized. Participants are considered not of child bearing potential if they are surgically sterile (i.e. they have undergone a hysterectomy, bilateral tubal ligation, or bilateral oophorectomy) or they are postmenopausal. 5. Willing and able to comply with the trial protocol (e.g. can tolerate MRI and fullfills the requirements for MRI, e.g. not fitted with pacemakers or permanent hearing aids), with ability to understand and complete questionnaires 6. Willing and able to provide written informed consent  Unable to give informed consent. 2. Patient with other types of multiple scelerosis (Secondary-Progressive MS (SPMS), Primary progressive MS, Progressive-Relapsing MS (PRMS) ) 3. Any medications that unfavourably interact with statins e.g.: fibrates, nicotinic acid, cyclosporin, azole anti-fungal preparations, macrolideantibiotics, protease inhibitors, nefazodone, verapamil, amiodarone, large amounts of grapefruit juice or alcohol abuse within 6 months. 4. Active Hepatic disease or known severe renal failure (creatinine clearance <30ml/min) 5. Screening levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) or creatine kinase (CK) are three times the upper limit of normal patients. 6. Patient unable to tolerate or unsuitable to have baseline MRI scan (e.g. metal implants, heart pacemaker) or MRI scan not of adequate quality for analysis (e.g. too much movement artefact). 7. Females who are pregnant, planning pregnancy or breastfeeding. 8. Allergy to simvastatin
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Multiple Sclerosis Signed informed consent 2. RRMS and/or PMS subtype 3. EDSS between 0 and 7.0 4. Express at least one high-affinity (Ala147) allele of the TSPO receptor for PBR28 5. Initiating Ocrelizumab treatment within the next 3 months  Hypersensitivity to trial medications 2. History of life-threatening reaction to Ocrelizumab 3. Acute or uncontrolled chronic medical condition 4. Impaired hearing 5. Claustrophobia 6. 300 lbs of greater (weight limit of MRI table) 7. Pregnancy or breastfeeding 8. Sensitivity to imaging agents 9. Contraindications to MRI 10. Use of benzodiazepines, topiramate, doxycycline, mynocicline
Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Multiple Sclerosis Multiple Sclerosis, Relapsing-Remitting Patient Engagement Self Efficacy persons with relapsing-remitting multiple sclerosis being ≥18 years old considering immunotherapy for mild/moderate or (highly) active courses of the multiple sclerosis  persons with secondary progressive multiple sclerosis or primary progressive multiple sclerosis persons with major cognitive deficits persons having poor German language skills persons who participated in the development phase of the PExMS-website, which took place prior to the pilot randomised controlled trial