semaj83/ctmatch_classification huggingface dataset:
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Tinea Pedis Subjects aged 18-65 years, who have been diagnosed with moccasin type tinea pedis (by positive dermatophyte culture, positive potassium hydroxide/calcofluor white preparation, and a Total Signs and Symptoms Score of at least 4) Females of childbearing potential must use contraceptive methods   Subjects who are receiving any CYP3A substrates with potential for QT prolongation have used systemic antifungal drugs within 30 days of first dose; or topical antifungals within 2 weeks of first dose Also excluded are those who have a clinically significant medical condition
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Dermatitis, Atopic Using the Hanifin and Rajka the patient has a diagnosis of moderate to severe atopic dermatitis Using the Rajka and Langeland grading system, the patient's atopic dermatitis score is at least 4.5 (moderate to severe)  Patient has a serious skin disorder other than atopic dermatitis Patient has history of eczema herpeticum (defined as an acute disseminated cutaneous herpes simplex type 1 or 2 infection associated with constitutional symptoms like fever, headache, malaise, regional or generalised lymphadenopathy in an individual with eczema)
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Diabetic Foot Ulcers Non-hospitalized ambulatory patients with diabetes mellitus Men or Women greater than 18 years old Patients must be considered reliable, willing and able to give consent Female patients must be postmenopausal for a least 6 months or surgically sterilized Localized infection of the ulcer that would ordinarily be treated on an outpatient basis Patients who have been previously treated or are currently under treatment for a localized infections of an ulcer may be enrolled in there has been an adequate response to treatment and ulcer is still infected Patient must have radiograph within two weeks of entry showing no evidence of cortical destruction consistent with osteomyelitis Patient must have a palpable dorsalis pedis or posterior tibial pulse in the affected foot Patient may not be taking or have received any other investigational therapy or approved therapy within 30 days prior to entry  Patients requiring concurrent local or systemic antimicrobials during the study period for other infections Patients who are currently treated or awaiting dialysis Patients who are unable to care for their ulcers Patients with known alcohol or substance abuse within 6 months or study entry Patients with significant GI problems or surgery that might interfere with the absorption of ofloxacin Patients who are currently receiving systemic corticosteroids, immunosuppressives, antivirals, radiation therapy or cytotoxic agents Patients who currently require treatment or a primary or metastatic malignancy or have systemically immunocompromising disease Previous enrollment in this study or previous treatment with MSI-78 Topical Cream Patients with gangrene or severely impaired arterial supply to any portion of the affected foot Other conditions considered by the investigator to be sound reason for disqualification
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Allergic Conjunctivitis Skin test positive Able to put drops in eyes Able to have tears collected
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 1.0-999.0,  Leukemia Myelodysplastic Syndromes Diagnosis of one of the following Acute myeloid leukemia Acute lymphocytic leukemia Myelodysplastic syndromes Disease meets 1 of the following In first complete remission (CR) In second CR In relapse No more than 50% blasts in bone marrow Not deemed eligible for standard transplantation regimens by the attending physician, or at high risk for relapse
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 16.0-999.0,  Dermatitis, Atopic Moderate to severe AD (Rajka & Langeland score) with lesions to the head and neck defined as 'red face' or 'facial eczema': erythema affecting at least 10% of the surface of the 'face' (head, neck, chest, nape of neck), due to long-term AD At least two flare-ups of 'facial' eczema during the 12 months prior to and, in the investigator's opinion, conventional treatment had proved ineffective or poorly tolerated Female patients of childbearing age: effective means of contraception throughout the period of the study and for four weeks following the end of the study Informed consent Therapeutic washout for atopic dermatitis treatments  Genetic epidermal barrier defect, such as Netherton's syndrome, or suffering from erythroderma Seborrheic dermatitis or contact dermatitis affecting the 'face', or any other facial erythema of non-atopic origin Clinical infection due to the VZV virus (varicella, zona), HSV1-2 viruses (herpes), verruca vulgaris or molluscum contagiosum Superinfected eczema Known hypersensitivity to macrolides or to any other excipient in tacrolimus 0.1% ointment Known hypersensitivity to one of the agents contained in the fluticasone 0.005% ointment preparation Ulcerated lesions, of whatever type Moderate to severe acne or rosacea Patients who participated at the same time in another clinical study or who had participated in another clinical study within 28 days prior to in the study Any type of substance abuse (including that of drugs and alcohol) or any mental disorder/psychological state which, in the investigator's opinion, might interfere with the patient's follow-up
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 20.0-999.0,  Fungal Infection Japanese Patients In Whom A Causative Fungus Is Detected Before Treatment With The Study Drug Or Patients With Strongly Suspected Deep-Seated Fungal Infection Due To Candida species (Spp.) Or Aspergillus Spp  Patients With Mycoses Other Than Ones Due To Candida Spp. Or Aspergillus Spp Patients Who Will Receive Other Systemic Antifungal Agents For The First Time In Screening Period
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 0.5-85.0,  Staphylococcal Infection Age 6 months to 85 years Able to complete the informed consent process or, if a minor, a parent or guardian who is able to complete the informed consent process; an assent form also will be completed for children age 7 and older Willing and able to complete the study protocol, study-related activities, and visits Diagnosis of uncomplicated skin and soft tissue infection (uSSTI), either cellulitis (defined as an inflammation of skin and associated skin structures) or abscess (defined as a circumscribed collection of pus), evidenced by at least 2 of the following localized signs or symptoms on the skin for at least 24 hours: 1. Erythema 2. Swelling or induration 3. Local warmth 4. Purulent drainage 5. Tenderness to palpation or pain Able to take oral antibiotic therapy, either in pill or suspension form  Hospital in-patient Hospitalization within the prior 14 days Residence in a long-term skilled nursing facility Requirement for hospitalization for skin infection or other condition Previous enrollment in this protocol Participation in another clinical trial within the previous 30 days Superficial skin infection only, including: 1. Impetigo 2. Ecthyma 3. Folliculitis 4. Infections that have a high cure rate after surgical incision alone (such as isolated furunculosis) or after topical or local measures Unstable psychiatric or psychological condition rendering the subject unlikely to be cooperative or to complete study requirements Active drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with the adherence or subject compliance with study requirements Systolic blood pressure > 180 mm Hg
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 12.0-999.0,  Genital Warts In good general health Diagnosis of external genital / perianal warts with at least 2 warts and no more than 30 warts Negative pregnancy test (for women who are able to become pregnant)  Women who are pregnant, lactating or planning to become pregnant during the study Evidence of clinically significant or unstable disease (such as stroke, heart attack) Have any of the following conditions: HIV infection; current or history of high risk HPV infection (e.g., HPV types 16, 18, etc.); outbreak of herpes genitalia in the wart areas; internal warts requiring or undergoing treatment; dermatological disease (e.g., psoriasis) or skin condition in the wart areas Have received specific treatments in the treatment area(s) within the designated time period prior to study treatment initiation
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Tinea Pedis Athlete's Foot Be at least 18 years or age and of either sex Has a clinical diagnosis of tinea pedis with at least i) moderate scaling(interdigital and/or moccasin) and ii) mild erythema (interdigital only) Be willing to give informed consent Be willing and able to give informed consent Has microscopic evidence (positive KOH) of the presence of fungi. Evaluable subjects must have a positive KOH and a fungal culture positive for a dermatophyte at Baseline. Subjects with a positive KOH may be entered into the study pending the results of the fungal culture Be in good health and free of any disease or physical condition which might, in the investigator's opinion, expose the subject to an unacceptable risk by study participation Women of childbearing potential must have a negative urine pregnancy test and agree to use an effective, non-prohibited form of birth control for the duration of the study (abstinence, stabilized on oral contraceptives for at least two months, implant, injection, IUD, patch, NuvaRing, condom and spermicidal or diaphragm and spermicidal)  Is nursing or planning a pregnancy during the study Has used topical antifungal or corticosteroid therapy or systemic antibacterial therapy within 30 days prior to the start of the study Has received systemic antifungal therapy within 12 weeks prior to the start of the study medication Has a history of diabetes mellitus or is immunocompromised (due to disease, e.g., HIV, or medications) Has concurrent tinea infection (in the opinion of the investigator). However, concurrent onychomycosis is allowed Has any other skin disease which might interfere with the evaluation of tinea pedis Is currently enrolled in an investigational drug or device study Has received an investigational drug or treatment with an investigational device within 30 days prior to entering this study Is unreliable, including subjects with a history of drug or alcohol abuse Has known hypersensitivity to any of the components of the study medications
Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 19.0-999.0,  Tinea Positive clinical findings for moccasin, interdigital or bullous tinea pedis as determined by direct clinical examination Must have a clinical symptom severity score of at least 20 on a possible 64 point scale Written informed consent must be obtained from the subject Must ≥ 19 years of age Must agree to avoid professional pedicures or application of any nail polish product or nail cosmetic to the toenails after the screening visit until the conclusion of the trial Must agree to take measures to avoid pregnancy during the 12 day (or 26 day if in cross over group) study period  Has a diagnosis of either psoriasis or eczema Has a visual diagnosis, by the investigator, of onychomycosis Use of topical antifungals e.g. (clotrimazole, ketoconazole,miconazole, oxiconazole- (Oxistat®, Glaxo Smith Kline), sulconazole, naftifine (Naftin®, Merz), terconazole, econazole nitrate (Spectazole®, Ortho-McNeil), butoconazole ,Fluconazole, ciclopirox olamine-(Loprox®, Medicis), tolnaftate, haloprogin), Zeasorb-AF , antibacterials and corticosteroids in the preceding 5 days of screening visit (Day 1) Use of systemic corticosteroids in the preceding 7 days of screening visit (Day 1) Use of systemic antifungals in the preceding 7 days of screening visit (Day1) including (terbinafine (Lamisil®, Novartis), Itraconazole (Sporanox®, Janssen), fluconazole (Diflucan®, Pfizer), ketoconazole, miconazole, griseofulvin (Gris-PEG®, Pedinol), butoconazole, terconazole, Potassium iodide) Has used any investigational drug(s) within 30 days preceding screening visit (Day 1)