semaj83/ctmatch_classification huggingface dataset:
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-35.0,  Endometriosis Age 18-35 years of age. Written and signed informed consent by the patient to participate in the study. Patients with regular menses, both ovaries, serum TSH within normal range, body mass index (BMI) <30 kg/m2 with normal sperm analysis of the husband  Patients with previous endocrine disorders. Cases in which the cause for infertility was other than endometriosis (except for patients with tubal obstruction, in the control group) Patient with previous surgery for endometriosis
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-38.0,  Endometriosis aged18-38 years clinically diagnosed with endometriosis (Stage I-IV) patient is seeking pain relief from symptoms of endometriosis/ pelvic pain/ dyspareunia/ dysmenorrhea  pregnancy or current breastfeeding use of hormonal suppression for symptom control (OCP, progestins, GnRHa) within past 3 months surgical treatment for endometriosis within last 3 months history of renal disease, liver dysfunction, myopathies in the past baseline AST, ALT or creatinine levels that are more than 1.5 times the normal limits current use of medications that may interact with statins (erythromycin, gemfibrosil, antifungals, antiretroviral, other cholesterol lowering drug etc)
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 20.0-45.0,  Adenomyosis Infertility Dysmenorrhea Premenopausal women aged 20-45 years having been diagnosed with adenomyosis earlier and have no other pathology of the uterus, regardless of clinical symptoms  Postmenopausal women Pregnant women Gynaecological cancer GnRH analog therapy or systemic hormone therapy in the last three months prior to hysterectomy Endometriosis Uterine fibroids
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 25.0-50.0,  Adenomyosis Premenopausal women aged 30 years old scheduled for vaginal, abdominal or laparoscopic total hysterectomy one or more of the following clinical symptoms: bleeding disorders (menorrhagia, irregular bleeding, hypermenorrhoea), chronic pelvic pain, dysmenorrhoea, or dyspareunia junction zone definable  postmenopausal women pregnancy gynecological cancer GnRH analog therapy or systemic hormone therapy in the last three months prior to hysterectomy junctional zone not identifiable
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 38.0-52.0,  Adenomyosis females complaining of pelvic congestion: dysmenorrhea, dyspareunia, chronic pelvic pain, menorrhagia, metrorrhagia  refusal of the patient to get enrolled in the study
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-37.0,  Deep Endometriosis Stage III Deep Endometriosis Stage IV female patient between 18 and 38 years endometriosis stage III or IV in the AFSr classification laparoscopy included deep endometriosis procedures (adhesiolysis, ureterolysis, cystectomy, resection of bowel, urinary or deep peritoneal endometriosis) written informed consent  previous adnexectomy or adnexectomy during surgery
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-90.0,  Constipation diagnosis of constipation according to Roma III complete bowel movements per week <3 total bowel movements per week <6 written informed consent  report of loose (mushy) or watery stool in the absence of laxative use ongoing artificial nutrition lactose intolerance chronic inflammatory bowel disease previous abdominal surgery use of anti-cholinergics use of antibiotics in the 6 weeks before baseline visit Radio chemotherapy Cognitive decline (Mini Mental State Examination <27)
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 21.0-999.0,  Leiomyoma Uterine Fibroids ≥21 years old Premenopausal (at least one menses in last 3 months) Symptomatic fibroids (fibroids visualized on ultrasound or MRI and heavy uterine bleeding, pelvic pressure or discomfort, urinary or bowel abnormalities, dyspareunia) Fibroids that are ≤4 in total number or Fibroids that are ≤7 in total number if all fibroids are less than 4cm (40 mm) each Fibroids that are ≤7cm in maximum diameter, on screening imaging, if ≤4 fibroids in total number(fibroid is defined as any mass with radiographic characteristics of fibroid >2cm) Up to date in Pap smear screening and surveillance Endometrial biopsy (required if age>45 years with irregular bleeding) does not indicate premalignant or malignant cells Agree to use non-hormonal barrier method of contraception during study period if at risk for pregnancy Has primary care provider or gynecologist Agrees not to start new medications/treatments for fibroids during the study  Fibroids treated by surgery, radiologic procedure, or GnRH agonist or antagonist in the last 3 months Any submucosal fibroid ≥2cm that is >50% in uterine cavity (FIGO Type 0 or Type 1 fibroids) amenable to hysteroscopic resection Use of exogenous estrogen and/or progestin in the last month. (for 3 month long-acting depoprovera injection, no use in last 3 months) Pregnant, lactating, or planning to become pregnant in the next 6 months Hematocrit <27% or visit to emergency room or hospitalization for fibroid symptoms in the last 3 months (cannot be safely randomized to a placebo) History of osteopenia or osteoporosis History of hyperlipidemia Current liver or kidney disease Unable or unwilling to attend 4 study visits Pelvic imaging concerning for gynecologic cancer or cancer of the genitourinary or gastrointestinal system
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-38.0,  Endometriosis Patients over 18 years Patients operated by laparoscopy for endometriosis in our department between 2006 and 2014  Patients under 18 years
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Endometriosis Quality of Life Pain Sexuality Anxiety Depression Infertility female >18 years fluent German Cases: diagnosis of endometriosis Control 1: no endometriosis, no chronic pain Control 2: no endometriosis, chronic abdominal/pelvic pain  male <18years not fluent in German
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-100.0,  Uterine Fibroid Able to give informed consent A type 3 uterine fibroid Sufficient physical condition to undergo deep sedation Waist circumference that allows positioning on the HIFU table top inside the MR bore  Contra-indication for MRI scanning according to the hospital guidelines Contra-indication to injection of gadolinium-based contrast agent, including known prior allergic reaction to any contrast agent, and renal failure (GFR <30 mL/min/1.73 m2) Surgical clips or considerable scar tissue in the HIFU beam path A total of more than ten fibroids Post or peri-menopausal status Fibroid size >10 cm in diameter Patient has an active pelvic infection Patient has an undiagnosed pelvic mass outside the uterus Patient who is not able to tolerate the required stationary prone position during treatment
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 0.0-17.0,  Guillain-Barre Syndrome ENTRY --Disease Characteristics-- Guillain-Barre syndrome (GBS): Progressive weakness of two or more limbs; Absence or reduced tendon reflexes; No atypical symptoms of GBS (e.g., Miller-Fisher variant); No pure sensory neuropathy; No prior history of GBS Disability at least grade 3 according to Guillain-Barre Study Group grading scale (unable to walk 5 meters without assistance); Must not have improvement of one or more disability grades prior to randomization in this study No paresthesias, numbness, or weakness that began more than 14 days before randomization in this study No CNS involvement --Prior/Concurrent Therapy-- Biologic therapy: No prior treatment with plasmapheresis or infusion of human immunoglobulin (IVIg) Endocrine therapy: No concurrent corticosteroids or other immunosuppressants (except for concurrent medical conditions, e.g., asthma) Radiotherapy: Not specified
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Bacterial Infections Group B Streptococcus This information currently is not available
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Hypothyroidism Male or female subjects >18 years of age Primary hypothyroidism ≥6 months duration arising from autoimmune hypothyroidism, thyroidectomy or radioiodine treatment Thyroxine dose ≥100 mcg/day No change in thyroxine dose in past 2 months Serum TSH of 0.1-4.8 mU/L Adequate contraceptive measures for women of childbearing age  Major systemic illness affecting quality of life or likely to affect participation in the study Treatment with T3 currently or in past 2 months History of thyroid cancer requiring suppression of TSH secretion by thyroxine Ischaemic heart disease – previous myocardial infarction, angina or coronary artery revascularisation Renal failure: serum creatinine >135 micromol/L Known liver disease with alkaline phosphatase or ALT >2x upper limit of reference range Bony fracture in past 3 months or Paget’s disease of bone Secondary (central) hypothyroidism or hypopituitarism
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 5.0-17.0,  Influenza Healthy children enrolled in the target schools Written informed consent obtained from the child's parent(s) if they agree to participate  History of severe hypersensitivity (anaphylactic response) to egg products or previous FluMist FluMist is licensed exclusively for use in healthy individuals age 5-49 years. Therefore children for whom annual receipt of inactivated influenza vaccine for specific medical condition(s) is recommended will not be eligible. These conditions Asthma, other chronic pulmonary diseases, kidney disease, metabolic disease, heart disease, or hemoglobinopathy Immunosuppression of child Severe immunosuppression of a household member Pregnancy Past history of Guillian-Barre Syndrome Aspirin therapy within 1 month prior to FluMist or the anticipated use of aspirin containing products for one month after FluMist administration Administration of any inactivated vaccine within 2 weeks or any live vaccine within 4 weeks prior to receipt of FluMist Received anti-influenza medication in the past 48 hours
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 8.0-17.0,  Hypothyroidism Patients should have clinical and biochemical evidence of hypothyroidism, T4 less than 5.0 ng /dl , fT4 less than 1.0 mcg/dl and TSH of more than 10. Patients with prolonged hypothyroidism should have growth failure and delayed bone age of at least 2 SD from the mean. Patients with short term hypothyroidism should have normal growth velocity and bone age Females 8 to 16 years old Males 9 to 17 years old Patients without any chronic medical conditions Availability of a parent or guardian to attend study visits with the patient and to be actively involved in the patient treatment plan Give written informed consent prior to any study specific screening procedure with the understanding that the patient has the right to withdraw from the study at any time without penalty  Taking medications that affect their growth. (eg. Systemic corticosteroids, anabolic steroids) Experiencing other health problems/conditions that affect their growth rate such as growth hormone deficiency, Cushing Syndrome, rickets, and chronic diseases Patients with any condition that is a contraindication for GH therapy would conditions such as an active tumor, impaired glucose tolerance, neurofibromatosis (worsening of neurofibromatosis), and hypertrophy of tonsils and adenoids with sleep apnea. Contraindications for patients for GNRHa therapy would a severe systemic reaction to GNRHa which is rare, osteopenia, and osteoporosis, because delaying puberty will worsen the condition Moving to a location that the patient will not be able to be followed by a pediatric endocrinologist Patient is not willing to continue with the study. -
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 0.0-0.192,  Congenital Chylothorax Infants with congenital chylothorax requiring thorax drain
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Hypothyroidism Defined group of women who tested positive for post partum thyroiditis in 1985 Control group randomly picked from those who tested negative
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 18.0-64.0,  Influenza Healthy Adults  Previous vaccination with an influenza Vaccine containing the H5N1 strain History of clinically significant medical conditions History of Guillian-Barre Syndrome or active Neurological disease
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Advanced Cancer Patient with drowsiness/sedation caused by opiate for > 3 days and its intensity more or equal to 3/10 (0 to 10 scale; 0 = no sedation, 10=worst possible sedation) Patient receiving a regular dose of a strong opioid for the treatment of cancer pain, and no dose changes or dose change within 50% for at least 48 hours.Regular administration, defined as short acting opioids oral or parenteral every 4 hours around clock, slow release oral opioids every 12 hs or 24 hs, or transdermal opioids every 72 hours. Strong opioids morphine, hydromorphone, methadone, fentanyl, and oxycodone Patient with relatively intact cognition defined by the Mini Mental State Examination according to age and educational level. A score of 24 or above is usually considered normal Patient willing to engage in follow up visit with a nurse by phone on day 2-7 (each day), 11 and 15 of the study and to return for follow up visit on day 8 of treatment. If patient is unable to come to clinic, assessment will be performed through telephone Sexually active females at risk of being pregnant with a negative urine pregnancy test Written consent form signed Patients are 18 years or older Concurrent radiation treatment (defined as 10 or less fractions for a palliative indication) is allowed Concurrent chemotherapy is allowed, if the first two cycles have been well tolerated (defined as no grade 3 or 4 non-hematological toxicity)  Major contraindication to donepezil i.e. hypersensitivity to donepezil or piperidine derivatives Patients in whom a major change in opiate dose, analgesia requirements, anesthetic procedures or general anesthetic is expected over the next seven days Treatment with anti-cholinergic agents (i.e., glycopyrrolate) Patients taking Methylphenidate Patients with tube feeding (due to difficulty of accurate assessing some of the symptoms such as appetite and anorexia) History of ongoing arrhythmia causing a rhythm other than a sinus rhythm
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 18.0-90.0,  Dry Eye Syndromes Signed and dated informed consent Male or female aged from 18 to 90 years old Known treated bilateral dry eye Dry eye syndrome confirmed by ocular examination with a fluorescein and/or lissamine green staining, BUT and Schirmer, performed within the last 12 months before Visit, for both eyes Bilateral symptomatology suggestive of dry eye defined by: at least one of the following ocular symptoms suggestive of dry eye (burning, stinging, dryness feeling, sandy and/or gritty sensation, light sensitivity, reflex tearing, ocular fatigue) and Questioning on patient’s feeling (score >=3) Fulfilling the following of dry eye syndrome in both eyes defined by: Keratoconjunctivitis defined by a lissamine green score ≥ 4 (Van Bijsterveld score) and Schirmer test <= 10 mm in 5 min or BUT < 10 s  severe dry eye symptom eyelid dysfunction severe progressive rosacea any relevant ocular anomaly interfering with ocular surface best corrected far visual acuity <= 1/10 history of ocular allergy traumatism, infection, inflammation within last 3 months ocular surgery and laser within the last 3 months lasik, laser, PKR within the last 12 months contact lenses
Patient description: A 56-year old Caucasian female complains of being markedly more sensitive to the cold than most people. She also gets tired easily, has decreased appetite, and has recently tried home remedies for her constipation. Physical examination reveals hyporeflexia with delayed relaxation of knee and ankle reflexes, and very dry skin. She moves and talks slowly.

Clinical trial eligibility criteria: eligible ages (years): 18.0-75.0,  Secondary Hypothyroidism Hypopituitarism Hyperlipidemias hypopituitarism of at least 3 axes (TSH plus gonadotropin, somatotropin, corticotropin or ADH deficiency) termination of surgical or radiation treatment of pituitary tumors at least six month before study entry BMI of 20 9 kg/m2 non-smoking status  history of cardiovascular or pulmonary diseases current thyroxin dosage > 1.6 µg/kg bw pregnancy epilepsy cerebrovascular diseases nodular goiter