semaj83/ctmatch_classification huggingface dataset:
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 21.0-70.0,  Depression Diagnosis of major depression with a current episode Hamilton Rating Scale for Depression score higher than 20 No response or intolerance to antidepressant medication in the current depressive episode  Current use of antidepressants Diagnosis of psychosis or anxiety disorder Current substance abuse Seizures or history of head trauma
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 6.0-20.0,  Posttraumatic Stress Disorder Depression Admission to the Shriners Hospital or Massachusetts General Hospital for an acute burn, injury, or reconstructive surgery following a burn Between the ages of 6 years Recent experience of an acute burn, injury, or surgery meeting the Diagnostic and Statistical Manual(DSM-IV) A1 stressor criterion Child's response to the stressor meets Diagnostic and Statistical Manual(DSM-IV) A2 response criterion Proficiency in either English or Spanish  No memory of the injury Current use of an anti-depressant Known hypersensitivity to sertraline Diagnosis of Bipolar Disorder Diagnosis of PTSD Mental Retardation Traumatic Brain Injury New onset or marked worsening of a seizure disorder
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Depression For depressed subjects Meets DSM-IV diagnostic for major depressive disorder Score of greater than 16 on the Hamilton Depression Rating scale (17 items) at study entry Agrees to use an effective form of contraception throughout the study For healthy volunteers Not currently taking any medications No lifetime history of major neurological, medical, psychiatric disorder, or head injury Agrees to use an effective form of contraception throughout the study  Current suicidal ideation that may make study participation unsafe Current serious or unstable medical illness (e.g., cardiovascular, kidney, liver, respiratory, endocrine, neurologic, or blood-related disease) History of seizure disorder History of or current DSM-IV diagnosis of any of the following psychiatric illnesses within 12 months of study entry: organic mental disorder, schizophrenia, schizoaffective disorder, delusional disorder, psychotic disorders not otherwise specified, bipolar disorder, mood congruent or mood incongruent psychotic features, substance dependence disorders (including alcohol) History of or current diagnosis of dementia, or a score of less than 26 on the Mini Mental Status Examination at screening History of multiple adverse drug reactions or allergic reaction to the study drugs Currently taking psychotropic drugs or antidepressant medications Clinical or laboratory evidence of hypothyroidism Failure to respond during current major depressive episode to at least one adequate antidepressant trial, defined as 6 weeks or more of treatment with 40 mg of citalopram per day (or its antidepressant equivalent) History of electroconvulsive therapy (ECT) within the 6 months prior to study entry
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Depressive Disorder Sign an informed consent form years of age or older Females not pregnant or breastfeeding or planning pregnancy and using an acceptable form of contraception Meet DSM-IV for dysthymia A screening IDS-C score of 17 or greater No history of serious or unstable medical disorder Not taking any significant concurrent medications Not currently receiving psychotherapy  Suffering from DSM-IV defined delirium, dementia, amnestic, or other cognitive disorders mental disorders due to a general medical condition factitious or somatoform disorders mental retardation or developmental disabilities substance or alcohol abuse within the last 3 months depressive disorders with current suicidal risk psychotic disorders including delusional disorder, somatic type dissociative disorder personality disorders sufficiently severe to interfere with study participation
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-70.0,  Bipolar Disorder Criteria:Patients must meet the following to be eligible to participate in the study Male or female outpatients, 18 to 70 years of age Female patients of childbearing potential must be using a medically accepted means of contraception Able to communicate intelligently with the investigator, and study coordinator Able to give informed consent DSM-IV diagnosis of bipolar I, bipolar II, cyclothymic disorder or bipolar disorder not otherwise specified, experiencing an acute exacerbation of their illness at Visit 1 (hypomania, subsyndromal depression, hypomania and subsyndromal depression, depression and hypomania, or depression if diagnosed with bipolar II) as verified by SCID-I/P CGI-BP Overall Severity score greater than or equal to mildly ill at Visit 1 Must have been on prior medications for at least 2 weeks (6 weeks for fluoxetine) immediately prior to study entry  Patients may not participate in the study if they have any of the following conditions Pregnant, nursing, or intending to become pregnant during the study Serious, unstable illnesses including hepatic, renal, gastroenterologic, respiratory, cardiovascular (including ischemic heart disease), endocrinologic, neurologic, immunologic, or hematologic disease such that hospitalization for the disease is anticipated within 3 months or death is anticipated within 3 years A history of seizure disorder History of leukopenia without a clear and resolved etiology DSM-IV substance (except nicotine or caffeine) dependence within the past month Judged clinically to be at serious suicidal risk Participation in clinical trial of another investigational drug within 1 month (30 days) prior to study entry Treatment with an injectable depot neuroleptic within less than one dosing interval between depot neuroleptic injections prior to study entry Treatment resistance, non-response, or intolerability with olanzapine by the investigator's judgment
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Depression Clinical diagnosis of unipolar major depression  Substance abuse Psychotic disorder History of severe head trauma
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Bipolar I or II Depression and Alcohol Abuse or Dependence MADRS >= 20 at screen and 18 at baseline YMRS =< 11 at screen and baseline DMS-IV for past manic or hypomanic episode based on the SCID DSM-VI for alcohol dependence or abuse based on the SCID Alcohol dependence/abuse confirmed by corroboration from family member Negative urine pregnancy test  Inability to give informed consent Inability to give reliable assessment of alcohol consumption Evidence of alcohol consumption one week prior to baseline Liver function tests greater than 3X upper limit of normal at screen History of active hepatitis or hepatic encephalopathy History of pancreatitis History of adverse reaction to divalproex sodium History of seizure other than directly associated w/prior alcohol withdrawl History of major head trauma with LOC > 10 min. or skull fracture Hisotry of hypertension or neurologic illness
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-70.0,  Bipolar Disorder Alcohol Dependence English or Spanish-speaking Age 18-70 Diagnosis of bipolar I or II Current mood state of depressed or mixed Alcohol use of at least 5 drinks in the past 7 days Current diagnosis of alcohol dependence  Bipolar disorders other than bipolar I or II disorders (e.g., bipolar NOS, or cyclothymic disorders, schizophrenia, schizoaffective disorder, or unipolar) Lifetime opiate abuse or dependence or any current use (including prescription drugs) Diagnosis of current dependence on substances other than alcohol (participants with only abuse of other substances are included. Dependence on caffeine and/or nicotine is allowed.) Severe or life-threatening medical illness (e.g., hepatic cirrhosis, congestive heart failure, terminal cancer) or labs consistent with serious medical illness (e.g., severe edema, atrial fibrillation, dangerously abnormal electrolytes) Pregnant or nursing female High risk for suicide defined as ≥2 suicide attempts in the past 12 months that required medical attention, or current suicidal ideation with plan and intent Prior therapy with naltrexone and/or allergic reaction to naltrexone Current therapy with acamprosate or disulfiram Member of a vulnerable population (Dementia, cognitively impaired, mental retardation, prisoner) Baseline YMRS or HRSD17 scores ≥ 30
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Depression Chinese ethnicity Currently depressed as determined by a total score of at least 16 on the CBCI scale Speaks and understands English or Chinese (including Mandarin, Cantonese, and Taiwanese dialect) Willing to participate in follow-up phone calls  Currently at risk for suicide Current unstable medical illness Current clinical or laboratory evidence of hypothyroidism Diagnosed with any of the following in addition to depression: organic mental disorder; schizophrenia; delusional disorder; psychotic disorder; bipolar disorder; mood congruent or mood incongruent psychotic features History of treatment by a psychiatrist within 4 months of study entry History of alcohol or substance abuse within 1 year of study entry
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 21.0-65.0,  Depression Diagnosis of recurrent major depression  Unstable medical illness Any other simultaneous psychiatric or medical illness of greater concern than depression (index episode of depression is not primary)
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Bipolar Disorder Diagnosis of bipolar disorder Currently in the third episode of mania or major depression History of one other episode of major depression within 5 years prior to study entry  Currently in the first episode of mania or schizo-affective disorder (manic type) Rapid cycling drug or alcohol abuse Unstable medical illness Pregnant Index episode caused by medically prescribed drugs
Patient description: The patient is a 47-year-old Asian woman complaining of persistent feelings of sadness. She lost interest in activities she used to enjoy. She states that her mood is mostly depressed for the past 3 weeks. She also lost her appetite , which led to about 5kg weight loss. She complains of loss of energy and feelings of worthlessness nearly every day. She is not using any drugs and she does not smoke. She doesn't drink alcohol. She used to exercise every day for at least 30 min. But she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was recently diagnosed with colon cancer and he is starting his chemotherapy. There is nothing remarkable in her past medical history and her drug history is only positive for Vit D3 1000 units daily. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Alcoholism Alcohol Abuse Hepatitis C Liver Disease Positive serology for current infection by hepatitis C viremia by PCR confirmation test; 2. Current alcohol use (past 30 days) as indicated by self-report (using AUDIT C questions); 3. Meets hazardous alcohol use as measured by the Alcohol Use Disorders Identification Test. per (National Institute on Alcohol Abuse and Alcoholism, 1995): 1. for women, 7 or more drinks per week or 4 or more drinks per occasion; 2. for men, 14 or more drinks per week or 5 or more drinks per occasion; 4. Not currently engaged (past 30 days) in VA specialty substance use disorder treatment or mutual help groups like AA/NA  Abstinent from alcohol use in last 30 days as indicated by self-report or less than hazardous use according to listed above by the AUDIT. 2. Patient is already engaged (past 30 days) in specialty substance use disorder treatment or attends self-help groups