semaj83/ctmatch_classification huggingface dataset:
Patient description: A 63-year-old man presents with cough and shortness of breath. His past medical history is notable for heavy smoking, spinal stenosis, diabetes, hypothyroidism and mild psoriasis. He also has a family history of early onset dementia. His symptoms began about a week prior to his admission, with productive cough, purulent sputum and difficulty breathing, requiring him to use his home oxygen for the past 24 hours. He denies fever. On examination he is cyanotic, tachypneic, with a barrel shaped chest and diffuse rales over his lungs. A chest x-ray is notable for hyperinflation with no consolidation.

Clinical trial eligibility criteria: eligible ages (years): 50.0-75.0,  Chronic Obstructive Pulmonary Disease male and female COPD with an FEV1 of under 60% of predicted non-smoker between 50 and 75 years old experiencing an acute exacerbation of COPD (24-48 hours, before treatment)  all inflammatory disease (HIV, cancer, renal and cardiac deficiency) hormonal dysregulation inferior limb pathology neuromuscular pathology history of tobacco or alcool abuse oxygen dependent
Patient description: A 63-year-old man presents with cough and shortness of breath. His past medical history is notable for heavy smoking, spinal stenosis, diabetes, hypothyroidism and mild psoriasis. He also has a family history of early onset dementia. His symptoms began about a week prior to his admission, with productive cough, purulent sputum and difficulty breathing, requiring him to use his home oxygen for the past 24 hours. He denies fever. On examination he is cyanotic, tachypneic, with a barrel shaped chest and diffuse rales over his lungs. A chest x-ray is notable for hyperinflation with no consolidation.

Clinical trial eligibility criteria: eligible ages (years): 40.0-75.0,  Chronic Obstructive Pulmonary Disease Post bronchodilator forced Expiratory Volume in 1 second (FEV1)/Forced Vital Capacity (FVC) ratio less than 0.7 Stable phase of COPD History of exposure to respirable silica dust, nonsmokers with no of passive exposure of tobacco smoke or history of exposure to aromatic hydrocarbons, nonsmokers with no of passive exposure of tobacco smoke or current tobacco smokers without history of occupational exposure COPD risk factor exposure (occupational or tobacco smoke) duration not less than 12 months Male Caucasian Age of 40 years old  history of biomass smoke exposure age less than 40 and above 75 years old current COPD exacerbation concomitant asthma tuberculosis and other pulmonary diseases allergic and autoimmune disorders active infections immunodeficiency, including HIV infection parasitological diseases malignancies
Patient description: A 63-year-old man presents with cough and shortness of breath. His past medical history is notable for heavy smoking, spinal stenosis, diabetes, hypothyroidism and mild psoriasis. He also has a family history of early onset dementia. His symptoms began about a week prior to his admission, with productive cough, purulent sputum and difficulty breathing, requiring him to use his home oxygen for the past 24 hours. He denies fever. On examination he is cyanotic, tachypneic, with a barrel shaped chest and diffuse rales over his lungs. A chest x-ray is notable for hyperinflation with no consolidation.

Clinical trial eligibility criteria: eligible ages (years): 18.0-85.0,  COPD, HEAD&NECK CANCER,SCREENING group of adult COPD patients Adult patients with smoking history and no clinical manifestation of COPD who will be recruited form the institute of pulmonary medicine and the otolaryngology outpatient clinic Adult patients with lung disease unrelated to smoking, i.e. bronchial asthma who will be recruited from the institute of pulmonary medicine  Patients with an acute disease or COPD exacerbation Pregnant patients Patients who were intubated ≤3 months prior to Patients with a medical history of surgical intervention in the upper airway Patients with a medical history of malignant disease in the upper airway Patients who underwent radiotherapy of head and neck
Patient description: A 63-year-old man presents with cough and shortness of breath. His past medical history is notable for heavy smoking, spinal stenosis, diabetes, hypothyroidism and mild psoriasis. He also has a family history of early onset dementia. His symptoms began about a week prior to his admission, with productive cough, purulent sputum and difficulty breathing, requiring him to use his home oxygen for the past 24 hours. He denies fever. On examination he is cyanotic, tachypneic, with a barrel shaped chest and diffuse rales over his lungs. A chest x-ray is notable for hyperinflation with no consolidation.

Clinical trial eligibility criteria: eligible ages (years): 40.0-999.0,  Pulmonary Disease, Chronic Obstructive Adverse Effect of Glucocorticoids and Synthetic Analogues Disease Exacerbation Informed Consent as documented by signature Age ≥40 years History of ≥10 pack-years of smoking (past or present smokers) Airway obstruction, defined as FEV1/FVC≤70% Current acute exacerbation of COPD by clinical defined by the presence of at least two of the following Change of baseline dyspnea Change of cough Change of sputum quantity or purulence  Diagnosis of asthma Initial necessity of hospitalization Women who are pregnant or breast feeding Premenopausal women with insufficient contraception and anamnestic risk for pregnancy Severe coexisting disease with life expectancy <6 months Diagnosis of tuberculosis Known severe immunosuppression or immunosuppression after solid organ or stem cell transplantation Inability to follow study procedures, e.g. due to language problems, psychological disorders, dementia, etc. of the participant Participation in another study involving an investigational drug Previous enrolment into the current study
Patient description: A 63-year-old man presents with cough and shortness of breath. His past medical history is notable for heavy smoking, spinal stenosis, diabetes, hypothyroidism and mild psoriasis. He also has a family history of early onset dementia. His symptoms began about a week prior to his admission, with productive cough, purulent sputum and difficulty breathing, requiring him to use his home oxygen for the past 24 hours. He denies fever. On examination he is cyanotic, tachypneic, with a barrel shaped chest and diffuse rales over his lungs. A chest x-ray is notable for hyperinflation with no consolidation.

Clinical trial eligibility criteria: eligible ages (years): 18.0-75.0,  COPD Asthma for Healthy Smoking Subjects Must have signed an informed consent indicating that they understand the purpose of and procedures required for the study and are willing to participate in the study Be between 18 and 75 years of age, inclusive, at informed consent Healthy as determined by a physician, based on medical history and physical examination Must have smoked regularly in the 12-month period preceding the screening visit and have a pack history of ≥ 5 pack years (number of pack years = number of cigarettes per day/20 x number of years smoked) for All COPD Subjects Must have signed an informed consent indicating that they understand the purpose of and procedures required for the study and are willing to participate in the study Aged between 40 and 75 years of age inclusive, at the time of signing the informed consent COPD diagnosis: Subjects with a diagnosis of COPD as defined by the American Thoracic Society (ATS)/European Respiratory Society (ERS) guidelines (Celli, 2004). Symptoms must be compatible with COPD for at least 1 year prior to screening and post-bronchodilator spirometry readings at screening Post-bronchodilator FEV1/FVC ratio of <0.7  for Healthy Smoking Subjects Any potential subject who meets any of the following will be excluded from the participating study Upper or lower respiratory tract infection within 4 weeks of the screening visit Positive test for alcohol at screening Taking prescription medication in the 14 days before screening Subjects whose primary consumption of tobacco is via methods other than cigarettes (manufactured or self-rolled). Primary methods of tobacco consumption that are excluded but are not limited to pipes, cigars and e-cigarettes Subjects who are unable to produce a total weight of at least 0.1 grams (g) of selected sputum at screening Urinary cotinine levels at screening < 30 ng/ml Subject is mentally or legally incapacitated Subject is an employee of the Sponsor or contract research organization (CRO), or a relative of an employee of the Sponsor or CRO Any other reason that the Investigator considers makes the subject unsuitable to participate
Patient description: A 63-year-old man presents with cough and shortness of breath. His past medical history is notable for heavy smoking, spinal stenosis, diabetes, hypothyroidism and mild psoriasis. He also has a family history of early onset dementia. His symptoms began about a week prior to his admission, with productive cough, purulent sputum and difficulty breathing, requiring him to use his home oxygen for the past 24 hours. He denies fever. On examination he is cyanotic, tachypneic, with a barrel shaped chest and diffuse rales over his lungs. A chest x-ray is notable for hyperinflation with no consolidation.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Pulmonary Disease, Chronic Obstructive Patients Male of Female, aged 18 years or above Attended the clinic as a patient Participant is willing and able to give informed consent for participation in the study  Patients The patient is unable or unwilling to give consent Health Care Professionals Male or Female, aged 18 or above Attended the clinic as a health care professional Participant is willing and able to give informed consent for participation in the study Health Care Professionals The health care professional is unable or unwilling to give consent
Patient description: A 63-year-old man presents with cough and shortness of breath. His past medical history is notable for heavy smoking, spinal stenosis, diabetes, hypothyroidism and mild psoriasis. He also has a family history of early onset dementia. His symptoms began about a week prior to his admission, with productive cough, purulent sputum and difficulty breathing, requiring him to use his home oxygen for the past 24 hours. He denies fever. On examination he is cyanotic, tachypneic, with a barrel shaped chest and diffuse rales over his lungs. A chest x-ray is notable for hyperinflation with no consolidation.

Clinical trial eligibility criteria: eligible ages (years): 0.167-17.0,  Community-acquired Bacterial Pneumonia History of and/or documented fever (rectal, ear, or oral temperature ≥38°C or axillary temperature ≥37.5°C) or hypothermia (rectal, ear, or oral temperature <35°C or axillary temperature <34.5°C) Chest radiograph infiltrates consistent with bacterial pneumonia (or pneumonia caused by atypical bacterial agents); if a subject is outpatient and starting on oral therapy, a radiograph is not required Presence of at least 2 of the following signs or symptoms Cough Difficulty breathing Production of purulent sputum Chest pain Grunting Hypotension Tachycardia, defined as follows  Ventilator-associated or hospital-acquired pneumonia >48 hours of systemic antibacterial therapy confirmed or suspected bacterial meningitis breast-feeding females positive pregnancy test
Patient description: A 63-year-old man presents with cough and shortness of breath. His past medical history is notable for heavy smoking, spinal stenosis, diabetes, hypothyroidism and mild psoriasis. He also has a family history of early onset dementia. His symptoms began about a week prior to his admission, with productive cough, purulent sputum and difficulty breathing, requiring him to use his home oxygen for the past 24 hours. He denies fever. On examination he is cyanotic, tachypneic, with a barrel shaped chest and diffuse rales over his lungs. A chest x-ray is notable for hyperinflation with no consolidation.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Peptic Ulcer Pulmonary Disease, Chronic Obstructive Dental Plaque COPD arm COPD Gold standard 2-4 Peptic ulcer arm H.pylori positive peptic ulcer  Physically unable to make it to the dental clinic
Patient description: A 63-year-old man presents with cough and shortness of breath. His past medical history is notable for heavy smoking, spinal stenosis, diabetes, hypothyroidism and mild psoriasis. He also has a family history of early onset dementia. His symptoms began about a week prior to his admission, with productive cough, purulent sputum and difficulty breathing, requiring him to use his home oxygen for the past 24 hours. He denies fever. On examination he is cyanotic, tachypneic, with a barrel shaped chest and diffuse rales over his lungs. A chest x-ray is notable for hyperinflation with no consolidation.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Multiple Sclerosis, Relapsing-Remitting Male or Female ≥ 18 years of age Patient has a clinically definite relapsing form of Multiple Sclerosis according to McDonald (2010 revision) Patient with an acute MS exacerbation as determined by their treating clinician Patient planning to initiate Acthar Gel for the treatment of an acute MS exacerbation Patient capable of providing informed consent  Patients with a diagnosis of Progressive MS Patients that require concomitant corticosteroid therapy Patients receiving experimental drug therapy Patients with a history of scleroderma, systemic fungal infections, ocular herpes simplex, or cancer within prior 5 years Patients who had recent surgery or have a history of or the presence of a peptic ulcer within 6 months prior to study entry, congestive heart failure, or sensitivity to proteins of porcine origin If female, pregnant or breast-feeding; or, if of childbearing age, an unwillingness to use appropriate birth control
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Normal PBPC Donors Eligible to be PBPC donor for allogeneic transplantation as determined by local institution  History of splenectomy Previous PBPC mobilization attempts Previous treatment with GCSF or GMCSF
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 18.0-85.0,  Pulmonary Embolism age between 18 and 85 symptomatic PE confirmed by: high probability lung scan, or intermediate probability lung scan and objectively confirmed deep vein thrombosis, or spiral CT-scan or pulmonary angiography or TE echocardiography normal blood pressure (SBP >100mmHg) RVD at echocardiography (see criteria) written informed consent  absence of RVD at echocardiography shock or hypotension (SBP < 100 mmHg) therapeutic heparin (UFH or LMWH) treatment for more than 48 hours prior to randomization administration of thrombolytic agents within the previous 4 days vena cava filter insertion or pulmonary thrombectomy within the previous 4 days chronic pulmonary hypertension or severe COPD hypertension defined as blood pressure >180/110 mm Hg (systolic BP >180 mm Hg and/or diastolic BP >110 mm Hg) on a single, reliable measurement during current admission at enrolling site prior to randomisation use of GP IIb/IIIa antagonists within the preceding 7 days significant bleeding disorders either at present or within the past 6 months active peptic ulceration
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 16.0-999.0,  Abdominal Injuries Thoracic Injuries Patients with life threatening vital problems: respiratory, circulatory (pulse > 120/min, blood pressure < 100 mmHg, refill > 4 sec, exterior blood loss > 500 ml) or neurologically (Glasgow Coma Score < 14, abnormal pupils) compromised patients Patients with a revised trauma score under 12 Patients with signs of fractures from at least two long bones Patients with clinical signs of flail chest/multiple rib fractures Patients with a clinically evident pelvic rim fracture Patients with signs of unstable vertebral fractures or signs of neural cord compression Patients involved in a high-energy injury mechanism Fall from height (> 3 m) As declared by prehospital emergency medical services  Patients suffering from a shock Class IIIB/IV Patients who need immediate neurosurgical intervention Pregnant patients Patients referred from other hospitals Patients who die at the emergency department
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Immune Thrombocytopenia (ITP) ITP with platelet count <30 x 109 /l after 2 weeks of treatment with prednisolon or during prednisolon tapering period i.e. from week three of prednisolon initiation. Patients with platelet count between 30 -50 are eligible if a higher platelet count is considered necessary, because of : concomitant medical illness predisposing to bleeding (hypertension, GI bleeding, bleeding diathesis, previous history of bleeding) concomitant medical condition requiring platelet blocking agents/ anticoagulation, persistent bleeding despite platelets > 30 x 109 /l, prior to surgery, or because of other patient related factors necessitating higher platelet count as occupation, hobby, psychological intolerability Subject is >18 years Subject has signed and dated written informed consent Subject is able to understand and comply with protocol requirements and instructions, and intends to complete the study as planned Females in fertile age should express willingness for use of contraceptive means for 6 months following the administration of the study drugs  Previous splenectomy, chemotherapy, treatment with anti-D Ig, rituximab, or immune-suppressive treatments other than corticosteroids, Dapsone or Danazol Underlying malignancy or previous history of malignancy in the past 5 years (except skin carcinoma) Pregnancy and lactation Not willing to participate in the study Expected survival of < 2 years Known intolerance to murine antibodies Females in child-bearing age not willing to use contraception for 6 months HIV-positive/AIDS-, Hepatitis -B virus positive or Hepatitis -C virus positive Patients with a definite Systemic Lupus Erythematosus (SLE) (> 4 of the American College of Rheumatology Criteria)
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 0.083-15.0,  Injuries and Wounds All asymptomatic trauma patients from 0 to 15 years old  Any pediatric trauma patients with clinical indications for CT scan
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Pain Adult ASA 1-2  Cardiovascular disease Former smoker Pregnant Nursing Asthma
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 35.0-999.0,  Pancreatic Cancer Persons 50 years or older with recently diagnosed diabetes (within 2 years), with at least one of the following: no family history of diabetes, abdominal discomfort, anorexia, weight loss, elevated serum CA 19-9, or those undergoing EUS with or without Fine Needle Aspiration (FNA) for pancreatic cancer screening ; OR Persons 35 years old or older with familial pancreatic cancer with 2 or more first degree relatives with pancreatic cancer; OR Persons 35 years old or older with Peutz-Jeghers syndrome; OR Persons 35 years old or older with suspicious clinical symptoms of pancreatic cancer, but had normal CT of the abdomen with iodinated contrast within 2 weeks  Persons with contraindication to iodinated contrast Allergy to iodinated contrast Renal insufficiency (serum creatinine > 1.5 mg/dl) Patients with contraindication to ionizing radiation Pregnancy Patients with previous pancreatic surgery Contraindication to secretin Allergy to secretin Acute pancreatitis