Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Rabies (LRG): Subjects must meet all of the following at the time of subject ID assignment: 1. History of dog, cat, mongoose, fox, ferret, skunk, bat or raccoon bite to trunk, leg, ankle or foot, or lick or scratch with, or of broken skin or mucous membrane saliva or neural tissue contamination, unprotected physical bat contact, scratch or saliva contamination of the head or neck without broken skin all ≤ 54 hours (Section 3.9.4 and 3.9.5) 2. Has completed the written informed consent process and signed informed consent document 3. Males and females 4. Is age equal or more than 18 years on Study Day 1 5. Agrees to stay in contact with the study site for the duration of the study, provide updated contact information as necessary, and has no current plans to move from the study area for the duration of the study 6. Lives within 2 hour journey by available transportation to study center 7. For female subjects: agrees to avoid pregnancy from Study Day 1 through Study Day 121. Women physically capable of pregnancy (not sterilized and still menstruating or within 1 year of the last menses if menopausal) in sexual relationships with men must use an acceptable method of avoiding pregnancy during this period. Acceptable methods of avoiding pregnancy a sterile sexual partner, sexual abstinence (not engaging in sexual intercourse), hormonal contraceptives (oral, injection, transdermal patch, or implant), vaginal ring, intrauterine device (IUD), or the combination of a condom or diaphragm with spermicide (NRG) Subjects must meet all of the following at the time of subject ID assignment: 1. History of dog, cat, mongoose, fox, ferret, skunk, bat or raccoon bite to any body part, lick or scratch with, or of broken skin, mucous membrane saliva or neural tissue contamination, or unprotected physical bat contact all ≤ 54 hours from PEP (Section 3.9.4 and 3.9.5) 2. Has completed the written informed consent process and signed informed consent document. 3. Males and females 4. Is age equal or more than 18 years on Study Day 1 5. Agrees to stay in contact with the study site for the duration of the study, provide updated contact information as necessary, and has no current plans to move from the study area for the duration of the study 6. Lives within 2 hour journey by available transportation to study center 7. For female subjects: agrees to avoid pregnancy from agrees to avoid pregnancy from Study Day 1 through Study Day 121. Women physically capable of pregnancy (not sterilized and still menstruating or within 1 year of the last menses if menopausal) in sexual relationships with men must use an acceptable method of avoiding pregnancy during this period. Acceptable methods of avoiding pregnancy a sterile sexual partner, sexual abstinence (not engaging in sexual intercourse), hormonal contraceptives (oral, injection, transdermal patch, or implant), vaginal ring, intrauterine device (IUD), or the combination of a condom or diaphragm with spermicide  Subjects must have had none of the following at the time of subject ID assignment: 1. Clinical evidence of rabies infection 2. Category 3 exposure > 54 hours before Study Drug receipt 3. History or serological evidence of previous rabies vaccination 4. Previous receipt of equine or human rabies globulin 5. History of hypersensitivity reaction to equine or human immunoglobulin. 6. Received immunoglobulin or blood products within 42 days before Study Day 1 7. Received any investigational drug therapy or investigational vaccine within 60 days before Study Day 1 8. Planned participation in any other investigational study during the study period. 9. Receiving systemic immunosuppressant medication such as systemic corticosteroids but not limited to systemic corticosteroids 10. History or laboratory evidence of any past, present, or possible immunodeficiency state including but not limited to any laboratory indication of HIV infection 11. Previous medical history that may compromise the safety of the subject in the study according to the opinion of the principal investigator 12. History or evidence on physical examination of any systemic disease or any acute or chronic illness that, in the opinion of the investigator, may interfere with the evaluation of the safety or activity of SYN023 13. Pregnancy (results of the urine pregnancy test MUST be known before enrollment)