semaj83/ctmatch_classification huggingface dataset:
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Acute Abdomen Acute Appendicitis Patient presented with the complaint of right lower abdominal pain Suspected acute appendicitis  Flank pain Previous appendectomy Pregnancy Unstable vital signs Frank peritonitis US performed before EP's examination
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 4.0-999.0,  Hemolytic Disorders Gallstones Diagnosis of a hemolytic disorder including spherocytosis, G6PD deficiency, thalassemia or sickle cell disease. 2. Patients with cholelithiasis or bile sludge. 3. Age greater than or equal to 4 years. 4. Ability to consent to and participate in the study and follow study procedures  Previous splenectomy (complete or partial) 2. Evidence of hemolytic crisis at the time of research enrollment 3. Patients with highly symptomatic gallstones who have planned surgical intervention 4. Known allergy or intolerance to UDCA 5. Existence of concurrent hepatic disease 6. Any other laboratory or clinical condition that the investigator considers clinically significant that could impact the outcome of the study or the safety of the patient
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 9.0-17.0,  Post Operative Pain Appendicitis Patients undergoing Appendectomy for acute non-perforated appendicitis Must be between 9-17 years old  n/a
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Appendicitis Other and Unspecified Acute Appendicitis Acute Disease Gastrointestinal Diseases Intra-abdominal Infection Age 18-60 years Clinical suspicion of acute uncomplicated appendicitis based on history, physical examination, laboratory findings evaluated by a senior surgeon  Age <18 years or > 60 years Pregnancy or breastfeeding Allergy to contrast material or iodine History of appendectomy Renal failure, creatinine-value greater than the upper reference value Diabetes mellitus and metformin medication Suspicion of peritonitis and appendiceal perforation Incapability to cooperate and give consent to participate in the study A severe generalized disease or condition
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 2.0-18.0,  Neuromuscular Blockade pediatric patients aged 2 to 17 years (+ 364 days) eligible for laparoscopy (diagnostic laparoscopy, appendectomy, cholecystectomy, nephrectomy, splenectomy, tumor biopsy, varicocele correction, testicular retention) fasting of at least 6 hours ASA (American Society of Anesthesiology score) score 1 or 2 signed informed consent of the legal guardian of the patient  disagreement of the patient or his/her legal guardian serious comorbidities renal or hepatic disorders ASA score ≥ 3
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 5.0-18.0,  Appendicitis All children 5-18 years of age, presenting to CHEO with perforated appendicitis (confirmed either in the operating room or diagnosed preoperatively according to radiological criteria), and managed surgically will be assessed for to participate. These patients may participate if baseline lab values of serum AST (SGOT), AL T (SGPT), LDH, triglycerides and hexokinase glucose are normal, complete physical exam is normal, hGC test is negative for pregnancy (if the patient is a female of reproductive age) and none of the  are present Any known co-existing gastrointestinal disease Uncertainty about the diagnosis Perforated appendicitis with diffuse abdominal fluid on imaging associated with a clinical picture of severe sepsis A known allergy to any of the antibiotics to be used in this trial An active neurological disorder Receiving medical treatment for a neurological disorder A history of blood dyscrasia, hypothyroidism or hypoadrenalism Hepatic disease Renal impairment
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 15.0-999.0,  Wound Infection Complication Scar patients with a clinical diagnosis of acute appendicitis  children under 14 are not included
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 1.0-60.0,  Appendicitis Both gender Appendicitis diagnosis Informed consent signed 60 age year old surgical confirmation of acute appendicitis Antibiotic prophylaxis  Appendicitis diagnosis in patients >60 years old No antibiotic prophylaxis No informed consent signed
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 0.5-999.0,  Malaria Male or female, aged over 6 months old Acute severe P. falciparum malaria or another indication to treat with IV artesunate. Defined as one or more of the following, occurring in the absence of an identified alternative cause, and in the presence of P. falciparum asexual parasitaemia Prostration OR obtundation BCS<3 (preverbal children) or GCS<11 (adults) Convulsion in last 24 hours Suspected acidosis, manifesting as acidotic breathing Respiratory distress manifesting clinically (nasal flaring/indrawing) or oxygen saturation <92% or respiratory rate >30/min History of anuria Jaundice and/or hemoglobinuria Hemoglobin <7 g/dl or hematocrit <20%  History of 2 or more doses of parenteral antimalarial treatment in the previous 24 hours History of allergy or known contraindication to artemisinins
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-100.0,  Stroke, Acute acute ischemic stroke in-patients  Patients who refuse participate
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 6.0-18.0,  Functional Nausea Functional nausea (normal endoscopy findings)  Gastrointestinal infection less than 2 weeks ago Known chronic gastrointestinal disease Use of drugs 2 weeks prior to starting the study
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 2.0-17.0,  Acute, Perforated Appendicitis Children who undergo an appendectomy for perforated appendicitis. (Appendicitis: Diagnosis is made intraoperatively by the surgeon. Diagnosis Method: The visualization of a gross defect in the appendiceal wall or the presence of intraperitoneal stool or a fecalith at the time of operation.)  Patients presenting with simple or gangrenous appendicitis Patients with a history of iodine sensitivity, thyroid disease or renal disease Patients undergoing interval or incidental appendectomy Patients/parents/legal guardians who are both non-English and non-Spanish speaking
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 16.0-99.0,  Acute Appendicitis all acute appendicitis patients underwent total laparoscopic appendectomy or laparoscopic assisted appendectomy  no written informed consent
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 15.0-999.0,  Perioperative Hyperoxygenation Wound Infection Clinical diagnosis or Radiological diagnosis of acute appendicitis. 2. Appendectomy through the Mc Burney incision  Patients with chronic obstructive pulmonary diseases. 2. Immunodeficiency disease. 3. Patients requiring midline incision. 4. Patients requiring general anaesthesia after failure of spinal anaesthesia. 5. Patients requiring higher oxygen in perioperative period
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 5.0-16.0,  Appendicitis children (age 5-16 years) clinical and /or radiological diagnosis (ultrasound [US] and/or CT scan) of acute non-perforated appendicitis written informed parental/legal guardian permission in accordance with local regulations and institutional policy written informed child assent or waiver in accordance with local regulations and institutional policy  suspicion of perforated appendicitis presentation with an appendix mass or phlegmon (on physical examination and/or imaging) non-operative management (2 or more rounds of intravenous antibiotics) initiated at an outside institution previous episode of appendicitis or appendix mass/phlegmon treated non-operatively current treatment for malignancy positive pregnancy test (if part of a clinical routine) diagnosis of Cystic Fibrosis (CF)
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Cold Agglutinin Disease Autoimmune Hemolytic Anemia CAD diagnosis defined by the combination of - 1. Chronic hemolysis 2. Cold agglutinin titer 64 or higher 3. Positive direct antiglobulin test when performed with polyspecific antiserum, negative (or only weakly positive) with anti-IgG, and strongly positive with anti-C3d 2. The presence of a clonal B-cell lymphoproliferative disorder defined by - 1. Monoclonal band by serum electrophoresis with immunofixation, and/or 2. CD20 positive lymphocyte population with cellular kappa/lamda-ratio higher than 3.5 or less than 0.9, using flowcytometric immunophenotyping of bone marrow aspirates 3. Indication for therapy, i.e. significant anemia and/or considerable cold-induced circulatory symptoms 4. Written informed consent  An aggressive lymphoma 2. Non-lymphatic malignant disease other than basal cell carcinoma of the skin. A history of probably cured cancer is not an criterion. 3. Known HIV infection 4. Acute or chronic hepatitis B or C 5. Liver failure or active parenchymal liver disease. Bilirubin levels higher than 51 mol/L (3.0 mg/dL) when due to hepatic impairment. Elevated serum bilirubin level due to hemolysis is not an criterion. 6. Pregnancy or breast-feeding 7. Patients of childbearing age who are not willing to use safe contraception during the entire study period and 6 months following its cessation 8. All contraindications to the study drugs will be regarded as  9. Age below 18 years 10. Inability to cooperate
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Suspected Appendicitis Laparoscopy for suspected appendicitis Age 18 years or older American Society of Anesthesiologist (ASA) class I-III Gives written and oral consent  Known inflammatory bowel disease Known autoimmune disease Chronic pain patient Presumed poor compliance Pregnant or breastfeeding In systematic treatment with glucocorticoids or other immunosuppressive treatment Known renal disease, GFR<30 Known liver cirrhosis Known heart failure, EF<40% Known glaucoma
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 6.0-999.0,  Acute Appendicitis Abscess All patients, age 6 and older, who present for an emergent or interval appendectomy to any one of the participating surgeons, meet the for the study. Assent from all minors (under age 18) was obtained  Pregnant patients, patients with mental handicap, Veterans, patients under 6 years old
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 16.0-999.0,  Hepatocellular Carcinoma Liver Cancer Histologically confirmed advanced HCC with cirrhosis resulting from hepatitis B, hepatitis C, alcohol-related liver disease or any other aetiology OR Histologically confirmed advanced HCC resulting from NASH with or without cirrhosis Patient is considered unsuitable for liver tumour resection and/or is refractory to radiotherapy and other loco-regional therapies At least one measurable lesion with target lesion size ≥ 1.0 cm as measured by MRI or CT Eastern Cooperative Oncology Group (ECOG) performance status of 0-1 Child-Pugh class A or B (up to B7) Eligible to undergo pre and post treatment mandated biopsies Acceptable laboratory parameters, as demonstrated by Platelets ≥ 70 x 10^9/L Serum albumin > 26 g/L ALT and AST ≤ 5 x ULN  Patients who have been treated with TACE or chemotherapy within the last 28 days Prior investigational drugs within the last 30 days Grade > 1 prior treatment-related toxicities (excluding alopecia) at the time of screening Patients with clinically significant cancer ascites Any episode of bleeding from oesophageal varices or other uncontrolled bleeding within the last 3 months prior to study treatment initiation Patients with history of haemorrhage or gastrointestinal perforation Patients administered with serum albumin within the last 7 days prior to the first study drug administration Known infection with human immunodeficiency virus (HIV) Patients with central nervous system (CNS), bone or peritoneal metastasis Patients presenting with marked baseline prolongation of QT/QTc interval defined as repeated demonstration of a QTc interval ≥450 ms (males) and ≥460 ms (females) using Fridericia's correction formula
Patient description: The patient is a 17-year-old boy complaining of severe migratory pain in the right lower quadrant of his abdomen that started four days ago. The pain is accompanied by nausea and vomiting. He was febrile with tenderness, rebound tenderness and guarding on palpation. His WBC was elevated with dominant neutrophils. CT scan showed evidence of acute perforated appendicitis with free fluid in the pelvis. Diagnostic laparoscopy revealed phlegmon with no other abdominal abnormalities. He is now a candidate for emergent laparoscopic appendectomy under general anesthesia.

Clinical trial eligibility criteria: eligible ages (years): 4.0-17.0,  Perforated Appendicitis Patients 4-17 years of age with perforated acute appendicitis diagnosed at time of appendectomy  Patients with a known severe allergy to penicillin (anaphylaxis), prior severe side effects from ertapenem or amoxicillin-clavulanate, pregnancy, or previous drainage procedure for abscess and/or fluid collection related to appendicitis