Patient description: The patient is a 15 year old girl with the history of recurrent bilateral headache. The attacks come 2 times or more per week and each episode lasts around a day or a half. The pain is pulsating in quality and severe in intensity, causing trouble in her routine physical activity. The attacks are associated with nausea and photophobia. She recently noticed that that there are more attacks around her menstrual period. She is diagnosed with the migraine headache and is under treatment. She is a high-school student and living with her both parents. She is a book worm and spend her free time in a public library near her home. She is also interested in writing stories and has several short stories in English. She rarely does exercise. Her BMI is 21 with the BP of 100/60. There is nothing remarkable in her physical exam.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Knee Osteoarthritis Knee pain and crepitus with active motion and morning stiffness < 30 minutes and age > 38 years old. 2. Knee pain and crepitus with active motion and morning stiffness < 30 minutes and bony enlargement. 3. Knee pain and no crepitus and bony enlargement. Participants will have to meet all of the following additional 1. Age > 38 years old. 2. Tricare beneficiary 3. Ability to read and speak English well enough to provide informed consent and follow study instructions 4. Knee OA is the participant's most physically limiting condition as determined by patient's self report. 5. Able to ambulate 20 meters (65.6 feet) feet without an assistive device. 6. Radiographic findings of knee OA  ) Presence of any medical "Red Flags" affecting the knee: 1. Tumor, neoplasm etc. affecting the knee 2. Current or past history of rheumatoid arthritis or similar rheumatic condition 3. Current or past history of gout or pseudogout affecting the knee 4. Active Infection in the knee within the past 12 months 2.) Inability to participate in the therapy plan prescribed by the treating therapist 3.) Any prior Physical Therapy for the knee in the past 12 months 4.) Injection to the knee joint within the previous 30 days 5.) Surgical procedure on either lower extremity within the past 6 months 6.) Any prior lower extremity joint replacement surgery 7.) A physical impairment unrelated to the knee that prevents the subject from safely participating in any aspect of the study 8.) History of cardiac, respiratory, or musculoskeletal disorders (e.g. amputation) that restrict lower extremity function. 9.) Any physical, psychological, or emotional condition that is more symptom producing, or activity limiting than their knee OA. 10.) Any condition that disrupts sleep more than knee OA, such as a sleep disorder or Obstructive Sleep Apnea 11.) Inability to speak/read English adequately to understand and provide informed consent 12.) Pregnant or intending to become pregnant in the next year 13.) Military service members in a WTU (Warriors in Transition Unit) or service equivalent or pending a medical evaluation board/discharge process. For non-military personnel, anyone that is pending or undergoing any litigation. 14.) WOMAC Score < 30 15.) Unable to provide informed consent to participate in the study