semaj83/ctmatch_classification huggingface dataset:
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 18.0-90.0,  Peripheral Arterial Disease Male or female subject 18 to 90 years, of any race Patients with proven Peripheral Arterial Disease (PAD) in Doppler Ultrasound and Ankle-Brachial Pressure Index (ABPI ≤ 0.9 in one leg) Subject with stable (>3 month) PAD Fontaine Stage II Aortoiliac vessels with no significant hemodynamic disturbances , as confirmed by recent (<30 days) clinical examination Subject has intermittent claudication and claudication pain of the calf Subject has stable intermittent claudication (>3 month and not more than one year) with initial claudication distance not more than 250 meters, as determined by treadmill test (3.2 km/h, 10% grade) Subject willing to participate as evidenced by signing the written informed consent Treatment with Aspirin or Clopidogrel for at least 7 days Willingness to undergo standardized walking exercise  Ankle-Brachial Pressure Index (ABI) above 0.8 in both legs. In Diabetic patients with no compressible arteries ABI above 40 mm/Hg of the higher pressure measured in both arms Inability to walk Chronic respiratory insufficiency (severe obstructive or restrictive) Coronary artery disease with angina Stroke, myocardial infarction or other acute vascular events in the last 3 months Mild-Severe congestive heart failure Degenerative or inflammatory hip, knee, ankle or foot joint lesions interfering with walking Spinal stenosis or disc lesions with lower limb motor sensory defects Leg trauma, limb or skin infection or edema Recent (6 months) abdominal, cardiothoracic, vascular or orthopedic (lower limb) surgery
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 50.0-85.0,  Chronic Limb Ischemia Non-Healing Ulcers Patients with established diagnosis of lower limb ischemic based on their symptoms of claudication, rest pain, non-healing ulcers or gangrene and other vascular laboratory tests that are currently used to make this diagnosis and have been scheduled for endovascular revascularization Age group between 50-85 Gender Male or Female Race all race and ethnicities  Patients with known cardiac disease new MI (within 3 months) Patients with hypertension with the systolic BP >200 or diastolic BP>110 on the day of testing Patients on supplemental O2 for chronic obstructive lung disease Bed-ridden subjects either due to chronic disability or neurological problems
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 40.0-999.0,  Peripheral Arterial Disease Subjects with peripheral arterial disease for more than 6 months Male or female with claudication secondary to lower extremity atherosclerotic arterial disease. (with limited IC but not incapacitated for walking on the level) confirmed with ankle/brachial pressures< or = to 0.9 in one or both legs) or who have had a previous intervention for peripheral arterial disease Over 40 years old Able to comply with protocol requirements Able to provide informed consent Subjects taking anti-platelet therapy medication must be on a stable dose for 3 months prior to as well as during the study Subjects taking lipid lowering medication must be on a stable dose for 3 months prior to as well as during the study  Patients with ischemic rest pain in limbs, ulceration, or gangrene At baseline, any condition that prevents walking on a treadmill History of major bleeding Patients with bowel disease (including Crohn's disease, celiac disease, peptic ulcer disease, irritable bowel syndrome and diverticulosis) Patients with an estimated life expectancy less than 2 years and with high baseline cardiac risk (post ischemic or diabetic cardiomyopathy with EF<40%, Canadian Cardiovascular Society Class 3 or 4 angina or need for coronary revascularization procedures) Moderate to severe renal failure Subjects that are on supplements other that those prescribed by their clinician for the entire duration of the study Fish limitations (no more than 2 fish meals per week) Gluten allergy Subjects with allergies to any ingredient in the study product or placebo
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Peripheral Arterial Disease Claudication Critical Limb Ischemia Has a Rutherford Clinical Category Score of 1 Has evidence of ≥ 50% stenosis or occlusion in the superficial femoral, popliteal, anterior tibial, posterior tibial and/or peroneal arteries, confirmed by angiography Has identifiable distal target vessel which upon completion of the intervention, is anticipated to provide re-constitution of blood flow to the foot Exchangeable guidewire must cross lesion(s), with ability of catheter to cross lesion Each discrete target lesion's length is ≤ 20 cm Reference vessel diameter is ≥ 1.5 mm and ≤ 7 mm  Has surgical or endovascular procedure of the target vessel within 14 days prior to the index procedure Has any planned surgical intervention or endovascular procedure within 30 days after the index procedure Has had a previous peripheral bypass affecting the target limb Has end-stage renal disease defined as undergoing hemodialysis for kidney failure Has presence of severe calcification in target lesion(s) Has in-stent restenosis of the target lesion Has an aneurysmal target vessel Has significant stenosis or occlusion of inflow tract that has not been revascularized prior to treatment of the target vessel Has perforation, dissection or other injury of the access or target vessel requiring additional stenting or surgical intervention prior to enrollment Has disease that precludes safe advancement of the SilverHawk/TurboHawk device to the target lesion(s)
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 0.0-0.019,  Cerebral Oxygenation Cerebral Blood Flow Prematurity Preterm infant (Gestational Age <37+0) Peripheral arterial catheter (ulnary or radial artery)  Complex organ malformation
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 30.0-999.0,  Peripheral Arterial Disease Peripheral arterial disease post surgery > 1 month No discharge of surgical incision Intermittent claudication post invasive treatment  Necrosis Above/below knee amputee Other conditions might affect peripheral vascular elasticity
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Essential Hypertension Is treated with antihypertensive therapy and has a post-washout mean sitting clinic systolic blood pressure greater than or equal to 160 and less than or equal to 190 mm Hg on Day, or has not received antihypertensive treatment within 14 days prior to Screening and has a mean sitting clinic systolic blood pressure greater than or equal to 160 and less than or equal to 190 mm Hg at the Screening Visit and on Day 1 Females of childbearing potential who are sexually active agree to routinely use adequate contraception, and can neither be pregnant nor lactating from before study participation to Screening to 30 days after the last study drug dose Has clinical laboratory test results within the reference range for the testing laboratory or the investigator does not consider the results to be clinically significant Is willing to discontinue current antihypertensive medications up to 3 weeks before enrollment  Has a mean clinic diastolic blood pressure (sitting, trough) greater than 119 mm Hg on Day 1 Has secondary hypertension of any etiology (eg, renovascular disease, pheochromocytoma, Cushing's syndrome) Has a recent history (within the last 6 months) of myocardial infarction, heart failure, unstable angina, coronary artery bypass graft, percutaneous coronary intervention, hypertensive encephalopathy, cerebrovascular accident or transient ischemic attack Has clinically significant cardiac conduction defects (ie, third-degree atrioventricular block, sick sinus syndrome) Has hemodynamically significant left ventricular outflow obstruction due to aortic valvular disease Has severe renal dysfunction or disease Has known or suspected unilateral or bilateral renal artery stenosis Has a history of cancer that has not been in remission for at least 5 years prior to the first dose of study drug Has poorly-controlled type 1 or 2 diabetes mellitus at Screening Has hypokalemia or hyperkalemia at Screening
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 18.0-75.0,  Painful Diabetic Neuropathy Age ≥ 18 years to 75 years Documented history of Type I or II diabetes with current treatment control (glycosylated hemoglobin A1c of ≤ 10.0%) Diagnosis of painful diabetic peripheral neuropathy in both lower extremities The physical examination component of the Michigan Neuropathy Screening Instrument Score (MNSI) is ≥ 3 at Screening Visual analog scale (VAS) score of ≥ 4 cm at Screening (0 cm = no pain cm worst imaginable pain) Stable treatment of diabetes for at least 3 months with no anticipated changes in medication regimen, and no new symptoms associated with diabetes Lower extremity pain for at least 6 months If female of childbearing potential, negative pregnancy test at screening and using acceptable method of birth control during the study  Peripheral neuropathy caused by condition other than diabetes Other pain more severe than neuropathic pain Progressive or degenerative neurological disorder Myopathy Inflammatory disorder of the blood vessels (inflammatory angiopathy, such as Buerger's disease) Active infection Chronic inflammatory disease (e.g. Crohn's, Rheumatoid Arthritis) Positive HIV or HTLV at Screening Positive Hepatitis B or C as determined by Hepatitis B core antibody (HBcAB), antibody to Hepatitis B antigen (IgG and IgM; HbsAB), Hepatitis B surface antigen (HBsAg) and Hepatitis C antibodies (Anti-HCV), at Screening or known immunosuppression or on chronic treatment with immunosuppressive drugs, chemotherapy or radiation therapy Stroke or myocardial infarction within last 6 months
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 18.0-72.0,  Critical Limb Ischemia Atherosclerotic ischemic peripheral vascular disease or Thromboangiitis Obliterans with Critical Limb Ischemia (Fontaine stages III and IV) Participant must match either a or b Ankle brachial index (ABI) ≤ 0.7 Doppler waveforms at posterior tibial artery and dorsalis pedis artery are monophasic with toe pressure < 30 mmHg A non-surgical candidate for revascularization e.g. prior vascular reconstruction, inability to locate a suitable vein for grafting, diffuse multi segment disease, or extensive infra-popliteal disease not amenable to a vascular graft Age > 18 years old The non-index leg may be treated only in the event and it full fills the same and  used in this protocol for the treatment leg Patients must be on maximal tolerated medical therapy for PVD including A) Cessation of smoking B) Referral to endocrinologist for control of HgA1c to < 7.0 mg/dl, control of hyperlipidemia with statins or other anti-hyperlipidemic drugs as indicated, control of hypertension as indicated C) Antiplatelet therapy with aspirin and / or cilostazol (unless medically contraindicated, e.g. bleeding or allergy) Popliteal vascular entrapment syndrome Lower extremity infection or infected ulcer Hypercoagulable state HIV positive HBsAg positive Uncontrolled arrhythmia, that is, persistence of an arrhythmia despite medical therapy Unstable angina Thrombocytopenia < 50,000/ul
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Peripheral Arterial Disease patients at the time of diagnosis of Fontaine grade II peripheral arterial disease (PAD), confirmed by hemodynamic evaluation (Doppler ultrasound) over 18 years old  patients had previously undergone revascularization patients were receiving treatment with statins patients with contraindications to statin use patients with coexistence of chronic inflammatory diseases or steroidal medication
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Peripheral Vascular Diseases Documented acute coronary syndrome (Unstable angina, non-Q-wave myocardial infarction, Q-wave myocardial infarction) or/and documented ischemic stroke/transient ischemic attack (IS/TIA)  Previously known symptomatic or asymptomatic PAD confirmed by one of the following diagnostic methods or interventions (documented in the patient's medical record) Non-invasive or invasive vascular diagnostic tools (e.g.: ABI, Toe-brachial index, Duplex ultrasound, Magnetic resonance angiography, Computer tomographic angiography, Contrast angiography) Previous related intervention (such as angioplasty, stenting, atherectomy, peripheral arterial bypass graft, other vascular intervention including amputation) Patients whose ABI cannot be measured accurately Patients already in a clinical trial or a product registry Hospitalized patients
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 20.0-30.0,  Ischemic Preconditioning healthy volunteers aging 20-30 years old no cardiac，hepatic or renal，peripheral vascular diseases be willing to enter our study and sign an written informed consent  younger than 20 years old or older than 30 years old having cardiac，hepatic or renal，peripheral vascular diseases refuse to enter our study or sign an written informed consent
Patient description: A 72-year-old man complains of increasing calf pain when walking uphill. The symptoms have gradually increased over the past 3 months. The patient had an uncomplicated myocardial infarction 2 years earlier and a transient ischemic attack 6 months ago. Over the past month, his blood pressure has worsened despite previous control with diltiazem, hydrochlorothiazide, and propranolol. His is currently taking isosorbide dinitrate, hydrochlorothiazide, and aspirin. On physical examination, his blood pressure is 151/91 mm Hg, and his pulse is 67/min. There is a right carotid bruit. His lower extremities are slightly cool to the touch and have diminished pulses at the dorsalis pedis.

Clinical trial eligibility criteria: eligible ages (years): 40.0-999.0,  Peripheral Arterial Disease Criteria:Healthy age-matched participants (acute phase of the study) Healthy volunteers, male or female, > 40 years of age Body Mass Index 18-30 Glycated hemoglobin <6.5% Fasting serum total cholesterol <4 mmol/L and triglycerides <2.5 mmol/L Blood pressure <140/90 mm Hg Ankle-brachial index of >0.9 Willing to comply with the protocol requirements Willing to provide informed consent Participants having completed another food-related study are eligible to participate if it has been more than 3 months since their participation   healthy age-matched participants (acute phase of the study) Currently smoking, or smoking within the last 6 months (Note: cigar smoking on an occasional basis will be permitted) Presence of a clinically diagnosed disease affecting the heart, liver, kidneys, lungs,gastrointestinal, endocrine or blood/immune systems that requires medical treatment Taking any prescribed medication within the last 3 months with the exception of anti-depressants, birth control and hormone (estrogen) replacement therapy Pregnancy Amputation of upper or lower extremity on both sides Has undergone a surgical procedure requiring local or general anesthetic within the last 3 months History of gastrointestinal reactions or allergies to dietary oils and other ingredients in banana bread such as wheat and eggs Daily consumption of omega-3 supplements  Peripheral arterial disease participants (acute and chronic phases of the study)