Patient description: The patient is a 20 year old Caucasian female presents to the clinic with one-sided vision lost and facial weakness, dysarthria and numbness lasting for 1 day. She visited her PCP and underwent brain MRI which revealed a single plaque in the brainstem. After few months, she experienced lower extremities weakness led to balance problem. The second MRI revealed another lesion in the left cerebral hemisphere. The diagnosis of Relapsing Remitting Multiple Sclerosis (RRMS) is confirmed after the second MRI. Her past surgical history is significant for a C-section 2 years ago and she has a one child. She is divorced and is not currently in any sexual relationship. She smokes 10 cigarettes per day and drinks alcohol occasionally. She is working as an editor in a publisher company and she is happy that she can keep working from home most of the time. She is under the treatment of RRMS from 7 months ago.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Relapsing Remitting Multiple Sclerosis Patients will be eligible to participate in the study if all of the following are met at both screening (V-1) and baseline (V0): 1. Female or male patients, aged between 18 and 60 years, inclusive 2. Signed and dated statement of informed consent 3. Diagnosis of RRMS according to McDonald's revision 2010 (Polman et al., 2011) 4. Interferon (IFN) beta-1b naïve 5. Expanded Disability Status Scale (EDSS) score of < 5.5 6. At least 1 documented relapse in the past year (defined as the appearance of a new clinical sign/symptom [one that had been stable for at least 30 days] that persisted for a minimum of 24 hours in the absence of fever) ---or-- a subclinical sign/symptom (defined as a Gd-enhancing lesion or a new T2 lesion demonstrated on MRI examination on a prior MRI that has been completed within 1 year of the screening MRI). The Screening (V-1) MRI should not be used for this determination. 7. No relapse in the 4 weeks prior to the screening visit (V-1). 8. Must be in a clinically stable or improving neurological state 4 weeks preceding the screening visit (V-1)  Patients meeting any of the following at screening (V-1) and baseline (V0) will not be enrolled in the study: 1. Relapse at the baseline visit (V0) or occurring within 4 weeks prior to the screening visit (V-1) 2. Intake of glatiramer acetate within 3 months prior to the screening (V-1) visit 3. Intake of previous immunotherapy or immunosuppressant treatment, within 4 months prior to the screening (V-1) visit 4. Intake of or previously received therapy with cladribine or alemtuzumab 5. An active viral, bacterial, or systemic fungal infection within 1 week of baseline (V0) 6. Use of systemic steroids within 3 weeks prior to the screening (V-1) MRI 7. Progressive disease 8. Level of liver enzymes 2.5 x the upper limit of normal 9. Abnormal renal function (estimated Glomerular Filtration Rate [eGFR] < 60 ml/min/1.73 m2 ) 10. Positive serology or history for Hepatitis B, C, or human immunodeficiency virus (HIV) 11. Serious or acute coronary diseases, defined by at least 1 of the following conditions Clinical symptoms of ischemic heart disease ST elevation or depression > 2 mm on the electrocardiogram (ECG) Clinical symptoms of cardiac failure and/or current medical treatment for cardiac failure Severe ventricular arrhythmia (frequent premature ventricular beats) Atrioventricular block at third level 12. Chronic use of non-steroidal anti-inflammatory drugs 13. History of any of the following Severe depression or suicide attempt Uncontrolled seizure disorder Cancer, excluding adequately treated basal cell carcinoma of the skin or adequately treated in situ carcinoma of the cervix