semaj83/ctmatch_classification huggingface dataset:
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-55.0,  Obesity Diabetes Cardiovascular Disease Aged 18 to 55 years BMI ≥ 25 kg/m2 BMI < 40 kg/m2 and weight ≤ 300 lbs (136 kg) Medical clearance from a primary care provider Plans to matriculate as a student at Framingham State University or work on campus throughout the academic year of enrollment in the study Willingness to eat and drink only the foods and beverages on the study menus during participation, with no food allergies or aversions Willingness to eat in the dining hall Willingness to abstain from consuming alcohol during participation  Change in body weight exceeding ±10% during prior year Recent adherence to a special diet Recent adherence to a vigorous physical activity regimen (e.g., participation in a varsity sport) Chronic use of any medication or dietary supplement that could affect study outcomes Current smoking (1 cigarette in the last week) Heavy baseline alcohol consumption (> 10 drinks/week) or history of binge drinking (≥ 5 drinks in 1 day, anytime in past 6 months) Physician diagnosis of a major medical/psychiatric illness or eating disorder Abnormal blood glucose, TSH, CBC, BUN, Creatinine ALT greater than 150% of the normal upper limit Plans for a vacation during the study that would preclude adherence to prescribed diet
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Asthma years of age or older Known Asthma The exacerbation is defined as moderate or severe Not currently enrolled as an active participant in another clinical trial of a medical therapy or device The patient or first degree family relative (in cases where the patient is intubated) has authorized his/her consent to participate in this trial. The patient will be asked to give his consent only after initial bronchodilator therapy  years of age or older Known thyroid disorders Subject where thyrotoxicosis is suspected Known heart disease Heart rate > 140
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-55.0,  Hyponatremia -Triathletes with previous experience in half-ironman  -Potential participants (triathletes) with a previous history of muscle disorder, cardiac or kidney disease or those taking medicines or supplements during the two prior weeks were discarded
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Graves' Disease Thyroid Disease Hyperthyroidism Adults ≥ 18 years Diagnosis of Graves Disease Appointment with endocrinologist to discuss treatment options for Graves Disease  Major barriers to participate in shared decision making or to providing informed consent (i.e. dementia, severe hearing or visual impairment)
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Obesity Male or Female 65 years old (inclusive) Weigh less than 350 lbs Body mass index (BMI) between 25-43 kg/m2 Willing to fast for 10 hours prior to examination Right handed  Diagnosis (by self report) of diabetes Diagnosis (by self report) of neurological condition Current or past alcohol or drug abuse problem Smoking Have internal metal medical devices including cardiac pacemakers, aortic or cerebral aneurysm clips, artificial heart valves, ferromagnetic implants, shrapnel, wire sutures, joint replacements, bone or joint pins/rods/screws/clips, metal plates, metal fragments in your eye, or non-removable metal jewelry such as rings Unable or unwilling to complete the imaging procedures for the duration of the MRI scan due to claustrophobia or other reason
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-55.0,  Oxidative Damage Healthy, non-pregnant subjects between 18 and 55 years of age. Apparently healthy is classified as A-1, A-2, or A-3 according to the American Heart Association http://circ.ahajournals.org/content/97/22/2283/T6.expansion.html Subjects have to achieve a classification of "local class" based on age-graded time USA Track & Field. The age-graded time is the finish time adjusted to that of an open division participant using a factor for age and gender. Thus, the times for women and older participants are adjusted downward, while the times for most open division participants (such as 25-year-old men) remain the same. For example, a 55 year old woman has to run 29 minutes 45 seconds or better to be in the study http://www.usatf.org/statistics/calculators/agegrading/ For a man the same age, the equivalent time would be 25 minutes 2 seconds. This is approximately 60% of the speed of the current world record time for that age Subjects who will abstain from taking any nutritional supplements for the duration of the study, including vitamins and mineral supplements (Exception, ferrous sulfate, elemental iron, Vitamin D, Calcium). Subjects will also abstain from taking any over the counter products (herbals, melatonin, St. John's Wort, etc…) for the duration of the study The  will be the following Under 18 and over 55 years of age; those who are not apparently healthy is classified as A-1, A-2, or A-3 according to the American Heart Association Subjects who are not able to run 5-km in the time required for their age and gender Subjects that will continue to take nutritional supplements, including over the counter products, for the duration of the study, including vitamins and mineral supplements (exception: Ferrous sulfate, Elemental iron, Vitamin D, Calcium) Subjects that are taking prescription medications with the exception of birth control Known allergy or sensitivity to milk thistle, Bacopa monnieri, Ashwagandha, turmeric (or ginger), tea, its parts, caffeine, tannins, or members of the Theaceae family
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Hypothyroidism Subclinical Hypothyroidism Hyperthyroidism Subclinical Hyperthyroidism Graves Disease Hashimoto's Thyroiditis Iodine Deficiency Genetic Susceptibility Aged equal or more than 18 years old at the time of sampling Malaysian citizen  Respondents who did not give consent
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Thyroid Goiter Thyroid Carcinoma Multinodular Goiter Graves Diseases Patients affected by benign thyroid disease undergoing thyroidectomy
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Graves Ophthalmopathy Graves Disease Eye Diseases Thyroid Diseases Endocrine System Diseases Eye Diseases, Hereditary Hyperthyroidism Autoimmune Diseases Immune System Diseases Clinical diagnosis of Graves' Orbitopathy Mild GO According to statemnt, patients with mild GO usually have any one or more of the following：mild soft tissue involvement, exophthalmos＜18mm, temporary, or no diplopia Clinical activity score lower than 3 Being euthyroid for at least 1 month before the date of No previous specific therapy for GO, except for local measures in 1 month before the date of Written informed consent is obtained  moderate-sever Graves' Orbitopathy Sight-threatening Graves' Orbitopathy Clinical activity score ≥ 3 Pregnant females as determined by positive (serum or urine) hCG test at screening or prior to dosing, or lactating females Uncontrolled diabetes or hypertension History of mental / psychiatric disorder Hepatic dysfunction (Alb, AST, ALT and Alkaline phosphates levels must be within normal range for eligibility) Renal impairment (Urea and Creatinine levels must be within normal range) Doxycycline allergy or intolerance
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Thyroid Neoplasms Goiter, Nodular Thyroid Nodule Graves' Disease Hyperparathyroidism Patient ≥ 18 years old Surgical indication for parathyroidectomy or thyroidectomy  Patients < 18 years old Patient with history of chronic opioid use Patient with chronic pain syndromes Patient with allergy to marcaine
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 20.0-999.0,  Graves Disease Patients with Graves disease
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Graves' Disease Group A: Untreated Graves' hyperthyroidism (or within 4 weeks of initiating ATD treatment) definition hyperthyroidism: TSH decreased, FT4 and /or FT3 increased definition Graves': diffusely enlarged thyroid gland either by palpation or echograpy, and/or homogeneous thyroid uptake at scintigraphy, or positive TSHRAb first episode or recurrence of Graves' hyperthyroidism minimal or no eye signs, defined as lid retraction / lid lag but no other signs Planned treatment with antithyroid drugs either titration regimen or block-and-replace regimen for 18 months Group B. Untreated Graves' hyperthyroidism (or within 4 weeks of initiating ATD treatment) with overt signs of GO as defined by Mild GO: patients whose features of GO have only a minor impact on daily life insufficient to justify immunosuppressive or surgical treatment. They usually have only one or more of the following: minor lid retraction (<2 mm), mild soft tissue involvement, exophthalmos <3 mm above normal for race and gender, transient or no diplopia, and corneal exposure responsive to lubricants) Moderate-to-severe GO: Patients without sight-threatening GO whose eye disease has sufficient impact on daily life to justify the risks of immunosuppression (if active) or surgical intervention (if inactive). Patients with moderate-to-severe GO usually have any one or more of the following: lid retraction R2 mm, moderate or severe soft tissue involvement, exophthalmos >3 mm above normal for race and gender, inconstant, or constant diplopia Sight -threatening GO: Patients with dysthyroid optic neuropathy (DON) and/or corneal  Previous or planned treatment with 131I or thyroidectomy (A&B); sight threatening GO requiring decompression (B); drugs interfering with the natural course of GO (A&B): steroids, immunosuppressants, thiazolidinediones, antibiotics / antifungals / antivirals (both topical and systemic for at least 4 weeks prior to recruitment to the study); acute diarrhea illness (gastroenteritis for at least 4 weeks prior to recruitment to the study); Drugs interfering with thyroid function (A&B): amiodarone, lithium, iodine supplements; Drug or alcohol abuse (A&B); no informed consent (A&B); Age less than 18 (A&B); Pregnancy (A&B)
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 3.0-55.0,  Xerostomia Hyperthyroidism Thyroid Cancer Patients who have been treated with radioiodine therapy Patients who have never received radioiodine therapy (negative control group)  Non-English speaking subjects will be excluded due to our lack of translation support resources at this time. Of note, participation in our study cannot benefit participants in any way
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-70.0,  Ophthalmopathy, Thyroid-Associated ◦Man or woman between 18-70 years TAO with CAS of ≥ 4 (less than 3 months) Euthyroid for at least 6 weeks  Dysthyroid optic neuropathy (DON) Ulcerative Keratitis Previous treatment with steroids for TAO (do not prophylaxis for TAO in connection with radio iodine treatment) Previous Treatment with Rituximab (MabThera®) Positive Hepatitis B or C serology Receipt of a live vaccine within 4 weeks prior RTX+MTX to randomization History of recurrent significant infection or history of recurrent bacterial infections Patient who may not attend to the protocol according to the investigators opinion Pregnancy or lactation Significant cardiac, including significant or uncontrolled arrhythmia, or pulmonary disease (including obstructive pulmonary disease)
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 8.0-999.0,  Obesity Eating Behaviors Healthy Volunteers Volunteers will qualify if they meet the following criteria Age 8 17 years Weight, height and BMI greater than or equal to 5th percentile for age and sex according to Centers for Disease Control and Prevention 2000 US standard Cognitively capable of completing study procedures (FSIQ greater than or equal to 70) Good general health based on a normal history and physical examination (with the exception of overweight and minor, well-controlled illnesses)  Individuals will be excluded (and provided treatment referrals as needed) for the following reasons History of major cardiovascular disease or any other serious obesity-related complication as assessed during history and physical exam. Individuals with untreated or major illnesses relating to the endocrine and/or cardiovascular systems are excluded because these illnesses will likely influence outcomes. Such obesity-related comorbidities hypertension (defined by age sex and height specific standards, and fasting hyperglycemia consistent with diabetes (fasting glucose > 126 mg/dL) Presence of other major illnesses: renal, hepatic, gastrointestinal, most endocrinologic (e.g., Cushing syndrome, untreated hyper or hypothyroidism), hematological problems or pulmonary disorders (other than asthma not requiring continuous medication). Non-serious medical illnesses, such as seasonal allergies, will be reviewed on a case-by-case basis Regular use of any medication known to affect body weight or eating behavior (e.g., many medications prescribed for attention deficit hyperactivity disorder, or ADHD). Medication use for non-serious conditions (e.g., acne) will be considered on a case-by-case basis Current pregnancy or a history of pregnancy. A negative pregnancy test before starting the study will be required for postmenarcheal girls Current and regular use of tobacco products and/or alcohol
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-79.0,  Thyroid Neoplasms patients with differentiated thyroid cancer recently underwent total thyroidectomy (within 6 months) pathological T1bN0 : Tumor size 1-2cm with no microscopic extension with multifocality (within three foci) T3N0 : Tumor size <=2cm with microscopic extension (less than strap muscle) T1-3N1a : 3 or less micrometastatic lymph node  differentiated thyroid cancer with aggressive variant, poorly differentiated thyroid cancer, medullary thyroid cancer, anaplastic thyroid cancer more than 2cm size of tumor gross extension (strap muscle or more) Number of dissected lymph node <3 thyroid cancer with distant metastasis previous remote history of thyroid cancer surgery history of cervical external beam radiation therapy previous history of comorbid cancer renal insufficiency (Ccr <30ml/min) women with pregnancy or breast feeding
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Cardiac Arrest Unconscious (Glasgow Coma Scale ≤6) ≥18 years old Admitted in ICU after successful resuscitation from CA Treated with TH targeted to 33°C  unavailable ONSD measurement within 24 hours after return of spontaneous circulation (unavailable investigator, early death, or major hemodynamic instability) Traumatic or neurological origin of CA Previous cerebrovascular disease Facial trauma affecting the orbits and/or eyeballs Previous history of ocular pathology such as exophthalmia, glaucoma or cataract
Patient description: A 46-year-old woman presents with a 9 month history of weight loss (20 lb), sweating, insomnia and diarrhea. She reports to have been eating more than normal and that her heart sometimes races for no reason. On physical examination her hands are warm and sweaty, her pulse is irregular at 110bpm and there is hyperreflexia and mild exophthalmia.

Clinical trial eligibility criteria: eligible ages (years): 20.0-85.0,  Graves' Disease aged between 20 and 85 years euthyroid Graves' disease  Patients who were not capable to complete the questionnaire due to severe cognitive dysfunction or under education were excluded from this study
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Depressive Disorders Depression Must meet for Major Depression Must be free of other mental or physical disorders that could cause depression, and also free from conditions that would typically participants from trials involving pharmacologic antidepressants Cannot be receiving other treatments or require immediate clinical attention
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Depressive Disorder Signed the informed consent Meet for major depressive disorder without psychotic features Have a level of understanding sufficient to provide informed consent and to communicate with the investigator and site personnel Have had at least one other major depressive episode prior to the one being experienced at study entry You are reliable and agree to keep all appointments for clinic visits, tests and procedures required by the protocol  You have had treatment with a drug within the last 30 days that has not received regulatory approval at the time of study entry Any women who are pregnant or breast feeding If you have any serious medical illnesses other than major depressive disorder If you have previously participated in a clinical trial for duloxetine Any previous or current diagnosis of bipolar, schizophrenia, or other psychotic disorders