semaj83/ctmatch_classification huggingface dataset:
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Metastatic Breast Cancer OF (MOST for first-line therapy • Histologically confirmed breast cancer with distant metastases Note A biopsy from the primary tumor or a metastasis can be used for diagnosis Patients with non-measurable lesions are eligible Patients with inoperable, locally advanced breast cancer with lymph node metastases other than ipsilateral locoregional (axillary, infraclavicular, parasternal) or other distant metastases are eligible Patients with bone metastases with or without bone targeted therapy (bisphosphonates, denosumab) are eligible Patients with de-novo Stage IV disease are eligible HER2-positive tumor according to central pathology testing for HER2  for first-line therapy • Prior chemotherapy for inoperable locally advanced or metastatic breast cancer Note Prior neoadjuvant/adjuvant chemotherapy is allowed if doses for anthracyclines have not exceeded 720mg/m2 and 240mg/m2 for epirubicin and doxorubicin, respectively Re-exposure to paclitaxel is permitted, if the last dose of taxane was given at least 1 year before randomization Re-exposure to vinorelbine is permitted, if the last dose of vinorelbine was given at least 1 year before randomization Prior anti-HER2 treatment for metastatic or inoperable breast cancer Note Prior neoadjuvant/adjuvant anti-HER2 treatment with trastuzumab and/or lapatinib is allowed • More than one endocrine treatment line for metastatic or inoperable breast cancer exceeding a duration of 1 month
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Thyroid Cancer Differentiated thyroid cancer treated by thyroidectomy and at least 1 ablation with 131-I > 5 months ago TSH < 4 imU/L  Pregnancy Known metastasis
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 40.0-75.0,  Hypothyroidism Thyroid Diseases Endocrine System Diseases 75 years old Diagnosis of overt or subclinical hypothyroidism in two occasions with a minimum interval period of three months  Pregnant or lactating women Severe hepatic or renal dysfunction Psychiatric disabilities, acute cardiovascular and cerebrovascular diseases, chronic respiratory diseases, familiar hypercholesterolemia, malignancy, cholelithiasis, pancreatitis, bowel diseases and other disorders influencing lipid and bile acid metabolism Taking lipid-lowering agents and other drugs influencing thyroid function, lipid and bile acid metabolism Obviously poor compliance
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 60.0-999.0,  Biomarkers of Stress in Emergency Physicians emergency physician  endocrine disease, pregnancy, recent extraprofessional deleterious life event (such as death of a near relative, divorce), any current illness, drugs used to modulate inflammatory diseases (corticosteroids, anti-inflammatory drugs, immunomodulatory drugs), or any drugs with a chronotropic effect taken over the previous six months (beta blockers, diltiazem, verapamil, anxiolytics or antidepressants)
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Breast Cancer Alopecia New diagnosis of breast cancer stage 1-2 Planning to undergo neoadjuvant or adjuvant chemotherapy with curative intent Chemotherapy must be planned for at least 4 cycles of full-dose anthracycline or taxane based chemotherapy regimen Defined as one of the following regimens Adriamycin 60mg/m2 with cyclophosphamide 600mg/m2 Epirubicin 90-100mg/m2 with cyclophosphamide 600mg/m2 Paclitaxel 80mg-90/m2 weekly (every three weeks constitute a cycle), or 175 mg/m2 every 2-3 weeks as a single agent Docetaxel 100mg/m2 as a single agent Docetaxel 75mg/m2 with cyclophosphamide 600mg/m2 Docetaxel 75mg/m2 with carboplatin AUC of 6 and trastuzumab at standard doses  Stage 3 or 4 breast cancer or any other concurrent malignancy including hematological malignancies (i.e. leukemia or lymphoma) Baseline alopecia (defined CTCAE v4.0 grade > 0, see appendix B for CTCAE v4.0 scale) Subjects with cold agglutinin disease or cold urticaria Subjects who are scheduled for bone marrow ablation chemotherapy Subjects receiving chemotherapy with concurrent anthracycline and taxane (AT or TAC) Male gender
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Cancer have stage III or IV cancer diagnosis able to understand English have a Karnofsky Performance Status (KPS) score of 60% (able to care for most of the personal needs) have fatigue and/or two other target symptoms have been cleared by their provider to engage low to moderate intensity physical activities  are hospitalized have lesion or metastasis of bone have a cardiac pacemaker have a history of seizure or loss of consciousness have been using a Wii Fit diagnosed cognitive impairment
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 25.0-65.0,  Obesity Prevention of Weight Gain. Men and women between 25 and 65 years of age Overweight or Class I or Class II BMI Walk without assistance Commit to a schedule of assessment visits  Physical impairment which would make the intervention very difficult, or unsafe according to the patient's physician including history of myocardial infarction, stroke, coronary bypass surgery or angioplasty in the last 6 months; peripheral artery disease, unstable angina or ischemia Enrolled within past year in a formal weight loss program Reported losing greater than 5% of current body weight in the previous 6 months Smoking Plans to move from the area Participating in another research study Clinically judged to be unsuitable for participation or adherence as determined by the participants physician Inability or unwillingness to provide informed consent
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Asthma years of age or older Known Asthma The exacerbation is defined as moderate or severe Not currently enrolled as an active participant in another clinical trial of a medical therapy or device The patient or first degree family relative (in cases where the patient is intubated) has authorized his/her consent to participate in this trial. The patient will be asked to give his consent only after initial bronchodilator therapy  years of age or older Known thyroid disorders Subject where thyrotoxicosis is suspected Known heart disease Heart rate > 140
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Hypothyroidism Consecutive pregnant women with L-T4 treated hypothyroidism followed at the outpatient clinic at the Endocrinology Unit, Herlev Hospital, Denmark during 2012
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-35.0,  Hashimoto's Thyroiditis Newly diagnosed (within 1 year) Hashimoto's thyroiditis by positive serum anti-TPO antibody or anti-thyroglobulin antibody Euthyroid state by serum free T4 and TSH level within normal limit  Pregnant, planning pregnant within 1 year, or lactating women Renal insufficiency, abnormal liver function test Hematologic diseases: anemia, agranulocytosis, thrombocytopenia G6PD deficiency, porphyria cutaneous tarda Allergy to 4-aminoquinoline compounds Known retinopathy or visual field defect disorders Already receive immunosuppression therapy
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Hypothyroidism Subclinical Hypothyroidism Hyperthyroidism Subclinical Hyperthyroidism Graves Disease Hashimoto's Thyroiditis Iodine Deficiency Genetic Susceptibility Aged equal or more than 18 years old at the time of sampling Malaysian citizen  Respondents who did not give consent
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 21.0-100.0,  Health Behavior adults age 21 and over referred by primary care physician for health coaching have telephone for follow-up English speaking  pregnant or trying to become pregnant
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 21.0-80.0,  Insomnia Primary Insomnia Chronic Insomnia to 80 years of age Insomnia sufferers enrolled, will meet Research Diagnostic for insomnia disorder score > 14 on the Insomnia Severity Index report insomnia for > 3 months have sleep difficulties > 3 nights per week score < 3 on the Epworth Sleepiness Scale (ESS) score > 40 on the Hyperarousal Scale and report an inability to nap in the daytime The normal sleepers enrolled will report general satisfaction with sleep and no sleep/wake complaints, score < 10 on the ESS, score < 35 on the Hyperarousal Scale, and deny a practice of routine daytime napping  sleep-disruptive medical condition (e.g., rheumatoid arthritis) current major psychiatric (Axis I) condition on the basis of a Structured Clinical Interview for Psychiatric Disorders (SCID) sedative hypnotic dependence and unwillingness/inability to abstain from these medications while in the study use of anxiolytics, antidepressants, or any other psychotropic medication an apnea/hypopnea index (AHI) > 5 or a periodic limb movement-related arousal index > 5 during on screening PSG that includes a full sleep montage to allow for detection/diagnosis of sleep-disordered breathing and PLMD female participants who have tested positive on urine pregnancy tests or planing on becoming pregnant during the study Additionally, self-described NS who meet for any sleep disorder and those insomnia sufferers who meet for a comorbid sleep disorder in addition to insomnia disorder will also be excluded
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 19.0-999.0,  Post Radiation/Chemotherapy Alopecia Presents With Hair Thinning. Post-burn Alopecia Presents With Hair Thinning. Cicatricial Alopecia Presents With Hair Thinning. Androgenetic Alopecia Presents With Hair Thinning Alopecia Due to Traumatic Injuries Presents With Hair Thinning. Alopecia Due to Skin Disease Presents With Hair Thinning. Subject is ≥ 19 years old Subject has hair thinning of any etiology and has chosen to undergo hair extensions treatment Subject has mental capacity to understand study guidelines and requirements (to maintain scalp hygiene, delicate combing, etc.) Subject has been evaluated by the investigator to have a scalp condition in the planned area of implantation that is acceptable for entering the study and currently is NOT suffering from skin problems at planned implantation site around it Subject has Good general health Woman of child bearing potential must have a negative pregnancy test Subject willing to sign a written informed consent form (ICF) and the post implantation maintenance protocol  Previous other synthetic hair implants or hair transplantation in the past six months. Subjects with previous Hairstetics' implants implanted less than 6 month prior to screening are allowed, if the implants are located in a different location on the scalp Currently suffering from skin problems at planned implantation site or around it that might affect the procedure and/or success as clinically evaluated by the investigator Currently receiving or have within the past 3 months received radiation and/or chemotherapy Currently using steroid product with Immunosuppressive treatment Impaired coagulation Serious illness that may affect subject compliance to protocol Subject is using illegal drugs Participating in other clinical study Known allergy or hypersensitivity to Nitinol or Nickel or Titanium
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-35.0,  Sleep Pregnancy Stillbirth Infant, Low Birth Weight Infant, Small for Gestational Age Infant, Very Low Birth Weight Fetal Growth Retardation Fetal Hypoxia ≥18 years old low-risk singleton pregnancy entering the last trimester of pregnancy (in range 26-30 weeks of gestation) residing in the Greater Accra Metropolitan Area or area served by the Korle Bu Teaching Hospital fluent in either English, Twi, or Ga  BMI ≥ 35 at booking (first antenatal appointment for current pregnancy) pregnancy complicated by obstetric complications (hypertension [pre-eclampsia, gestational hypertension, chronic hypertension], diabetes [gestational or not], or intra-uterine growth restriction [<10th %ile for growth]) sleep complicated by medical conditions (known to get <4 hours of sleep per night due to insomnia, or musculoskeletal disorder that prevents sleeping on a certain side [e.g., arthritic shoulder]) multiple pregnancy known fetal abnormality maternal age >35
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Diabetes Weight Gain Weight Loss Cardiovascular Disease Obesity Participants will be men of European (self-report of both parents of white European origin) or South Asian (self-report of both parents of Indian, Pakistani, Bangladeshi or Sri Lankan origin) with BMI <25 kg.m-2, who have been weight stable (± 2 kg) for >6 months  will diabetes (physician diagnosed or HbA1c ≥6.5% on screening), history of cardiovascular disease, regular participation in vigorous physical activity, current smoking, taking drugs or supplements thought to affect carbohydrate or lipid metabolism, or other significant illness that would prevent full participation in the study
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 4.0-18.0,  Hashimoto Thyroiditis Graves Disease For HT A positive titers of antithyroid peroxidase (anti-TPO) or antithyroglobulin (anti-Tg) antibodies and at least one of Abnormal thyroid function that requires substitution treatment with L-thyroxine (TSH > 5 μIU/ml and decreased or normal levels of fT4 or fT3) Increased volume of thyroid gland (goiter) Morphological changes on ultrasound of the thyroid gland For GD A positive titers of thyroid stimulating antibodies (anti-TSI) and Decreased TSH levels and increased levels of fT4 or fT3 For Controls Otherwise healthy children and adolescents, age  Not Caucasian origin or affinity among participants Age of diagnosis above 18 years Disease duration below 3 months
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Hypothyroidism Neoplasms Postoperative Complications Biopsy proven head and neck cancer, as defined by AJCC staging system Treated with surgery in Edmonton, Alberta Treated with curative intent Diagnosis of sub-clinical hypothyroidism after head and neck surgery (TSH 4-10mIU/L, and free T4 10-24pmol/L)  Head and neck cancer of the thyroid gland, or other subsite involving the thyroid gland Underwent previous treatment for a different head and neck cancer History of radiation therapy and or chemotherapy to the head and neck History of thyroid disease as follows Hypothyroidism Hyperthyroidism Autoimmune thyroid disease including Grave's disease and Hashimoto's thyroiditis History of thyroiditis History of diabetes mellitus History of long term steroid usage
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 8.0-15.0,  Type 1 Diabetes Stress Informed consent signed by a parent/legal guardian and informed assent signed by the study participant prior study entry Diagnosed with Type 1 DM/Hashimoto thyroiditis prior to signature of Patient Informed Consent (PIC) (for the T1D group) Age between 8-15 years old (inclusive) at signature of PIC Treated by the investigator's centre prior signature of PIC (For the T1D and HT group) Willing to undergo all study procedures  Any documented concomitant chronic disease known to affect diabetes control (e.g. altered renal function, active cancer undergoing treatment, Crohn's disease, ulcerative colitis, Mb Addison disease) Any other medical, social or psychological condition that, in the investigator's opinion, makes the patient unable to comply with the study protocol (e.g. intellectual disability)
Patient description: A 25-year-old woman presents to the clinic complaining of prolonged fatigue. She denies difficulty sleeping and sleeps an average of 8 hours a night. She also notes hair loss, a change in her voice and weight gain during the previous 6 months. She complains of cold intolerance. On examination she has a prominent, soft, uniform anterior cervical mass at the midline.

Clinical trial eligibility criteria: eligible ages (years): 20.0-80.0,  Head and Neck Neoplasms Patients aged 20 to 80 years scheduled to receive neck dissection due to head and neck cancer  history of coagulation disorders prior radiation to the neck prior neck dissection declined to participate