semaj83/ctmatch_classification huggingface dataset:
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Colorectal Neoplasms Metastatic colorectal cancer Histologically or cytologically proven colorectal cancer Measurable disease on CT scan with at least one lesion >/= 2cm diameter (to allow adequate scout infusion imaging) Expected survival of at least 4 months ECOG performance status 0-2 Vital laboratory parameters should be within normal range including Neutrophils >/= 1.5 x 10^9/L Platelets >/= 150 x 10^9/L Serum bilirubin </= 34 micromol/L calculated creatinine clearance > 50 ml/min  Previous treatment with capecitabine Untreated active metastatic disease to the central nervous system (new or enlarging lesions on CT or MRI), or within 3 months of treatment (ie surgery or radiotherapy) for brain metastases Other serious illnesses, eg, serious infections requiring antibiotics, bleeding disorders Liver involvement with metastatic disease > 50% liver volume Chemotherapy, radiation therapy, or immunotherapy within 4 weeks before study entry (6 weeks for nitrosoureas) Previous external beam irradiation except if: (i) it was for standard adjuvant pelvic radiation for rectal cancer; (ii) it was for localised irradiation for skin cancer; or (iii) the sum total of all previous external beam irradiation port areas is not greater than 25% of the total red marrow Previous treatment with a monoclonal antibody or antibody fragment AND a positive huA33 HAHA titre Concomitant treatment with systemic corticosteroids. Topical or inhalational corticosteroids are permitted Mental impairment that may compromise the ability to give informed consent and comply with the requirements of the study Lack of availability of the patient for clinical and laboratory follow-up assessment
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Skin Cancer Male or Female and over 18 years of age Patients undergoing an examination of their skin Patients with a lesion(s) in one of the five categories: basal cell carcinoma, squamous cell carcinoma, pre-cancer lesions, pigmented lesions, and benign lesions Patients whose lesion also warrants a biopsy Signed informed consent document  Patients with absence of skin lesion(s) in one of the five categories Patients whose identified lesion did not need a biopsy Patients who did not sign the informed consent and agree to participate
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Skin Rash receiving bone marrow transplant -  not receiving other growth factors
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 45.0-999.0,  Venous Insufficiency Aged 45 years and older CEAP classification: stage C4 (changes in skin and subcutaneous tissue secondary to CVDs)4a (pigmentation or eczema) 4b (lipodermatosclerosis or atrophie blanche) C5 (healed venous ulcers) Ankle brachial index (ABI) 0.9 3mm Hg 0 absence of peripheral arterial disease Intact skin sensation measured with 10 gram monofilament Intact thermal sensation measured with thermal sensory tester at lower leg skin and foot surfaces Agreement to wear compression garments such as wraps or stockings during waking hours Phone, e-mail, or mail accessible Working freezer  ABI < 0.8 mm Hg or > 1.3 mm Hg -presence of lower extremity arterial disease (reduces skin temperature) Active systemic or localized infections such as cellulitis (raises skin temperature) Autoimmune disorders that reduce blood flow such as Raynaud's phenomenon Body temperature > 37.6 degrees C (febrile state raises skin temperature) CEAP classification c6: active venous ulcer (cooling ulcerated skin might impair healing) Known peroneal nerve injury Impaired skin sensation Unable to detect light touch measured with a 10 gram monofilament at lower leg skin surfaces Unable to detect not/cold sensation measured with thermal sensory tester at lower leg skin surfaces Not wearing compression or not agreeing to wear compression wraps or stockings
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 5.0-10.0,  Molluscum Contagiosum, Skin Disease Anyone aged 5-10 years with the clinical diagnosis of molluscum contagiosum  Anyone with immunosuppression including HIV or previous organ transplantation Anyone taking immunosuppressive medications Anyone who has previously received treatment with cantharidin Any female who has had her first menstrual period
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Carcinoma, Advanced Metastatic Histologically confirmed advanced or metastatic non-curable solid tumor (if limited to a single lesion and not a candidate for curative surgery or radiation therapy) Completed ≥1 conventional therapy Clinically indicated surgery or procedure to collect available tumor in sufficient quantity ("golf ball size," pleural or ascites fluid may also be collected) for vaccine processing Subjects that have completed all acceptable therapies that are the current standard of care for their respective diseases Recovered from all toxicities related to prior therapies Subjects with brain metastases treated at least ≥2 months prior to enrollment, without related clinical symptoms and must have a stable neurological exam on the screening evaluation ≥1 measurable or evaluable lesion Age ≥18 years ECOG performance status (PS) 0-1 Normal organ and marrow function  Surgery involving general anesthesia, chemotherapy, radiotherapy, steroid therapy, or immunotherapy within 4 weeks prior to entering the study Patient must not have received any other investigational agents within 30 days prior to study entry Patients with known brain metastases unless treated and stable for ≥2 months Patients with mucinous adenocarcinoma Short term (<30 days) concurrent systemic steroids ≤ 0.125 mg/kg prednisone per day (maximum 10 mg/day) and bronchodilators (inhaled steroids) are permitted; other steroid regimens and/or immunosuppressives are excluded. Patients requiring steroids following previous CNS radiation for metastatic disease are excluded Prior splenectomy Prior malignancy (excluding nonmelanoma carcinomas of the skin) unless in remission for ≥2 years Kaposi's Sarcoma Uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements Patients who are pregnant or nursing
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Effects of Chemotherapy patients receiving docetaxel as mono or combination therapy patients with no nail disorders at the start of treatment life expectancy of at least 3 months  patients previously treated with taxane chemotherapy Raynaud's phenomenon distal metastases ungual pathology arteriopathy cold intolerance peripheral neuropathy of grade 2 or higher patients currently enrolled in clinical trials
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Melanoma Patients or volunteers with or without a history of melanoma One or more palpable skin or subcutaneous lesions for which at least one of the following is true A tissue diagnosis has been made for the lesion(s) in question, by prior cytologic or histologic evaluation (Category A1) A tissue diagnosis will be obtained for the lesion(s) in question by cytologic or histologic evaluation (Category A2) A tissue diagnosis is not available, but a clinical diagnosis of melanoma or benign lesion is available with a high degree of confidence. Examples are hemangiomas, skin tags, seborrheic keratoses, dermatofibromas, lipomas, or growing pigmented skin lesions that are comparable to other cutaneous metastases of melanoma in the same patient (Category B) All patients must have the ability and willingness to give informed consent and must be age 18 years or older at the time of study entry  Known or suspected allergy to the adhesive skin markers or water-soluble ink used for the labeling of lesions Very fragile skin that may be susceptible to injury from adhesive markers Patients in whom there is a medical contraindication or potential problem in complying with the requirements of the protocol, in the opinion of the investigator
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Skin Cancer Men and women over the age of 18 Skin lesion suspected to either BCC or SCC etc Patient was referred for biopsy diagnostic/therapeutic before hand, and regardless of confocal microscope examination, according to the clinical consideration of physician  Pregnant women Children
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-75.0,  Basal Cell Carcinoma Study subjects must have had diagnosed at least one benign or malignant skin lesion Subject is from 18-75 years of age, inclusive Subject must sign and date all informed consent statements  Subject is exhibiting signs of a bacterial or viral infection, including fever Subject is unwilling to allow a biopsy of a malignant lesion for histological analysis
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  RECTAL NEOPLASMS Diagnosed with a large non-pedunculated rectal adenoma (sessile or flat) with a largest diameter of ≥2 cm (estimated by an opened resection snare of 20 or 30 mm) The lower and upper borders of the adenoma are located at ≥2 cm and ≤15 cm from the anal verge, respectively Biopsies of the lesion did not show malignant neoplastic tissue on histopathological evaluation; only lesions with low or high grade dysplasia are suitable for inclusion During flexible video endoscopy there are no signs of endoscopic suspicion for submucosal invasive cancer (Kudo pit pattern type V; excavated/depressed type morphology; fold convergence; or large smooth nodule >1 cm in a flat lesion) (33). In case of doubt, patients will undergo EUS as described at (2) In case doubt remains after flexible video endoscopy, endoscopic ultrasonography (EUS) of the rectal adenoma should invasion into the submucosal layer and pathological lymphadenopathy (lymph nodes >1 cm). When pathological lymph nodes are present, fine needle aspiration will be performed to lymph node metastasis (N+ disease) If not performed already, total colonoscopy will be done to detect and remove all synchronous colonic adenomas or cancers first. Cecal intubation must be confirmed by identification of the appendiceal orifice and ileocecal valve The general health condition of the patient permits general anesthesia (ASA classification I-III) Absence of non-correctable coagulopathy (international normalized ratio >1,5, or platelet count <90 × 109/l) Patient age of 18 years or older  Preoperative histologically detected malignancy Previous anorectal surgery Contraindications to general anaesthesia
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 0.0-2.0,  Hemangioma Patients with ages up to 2 years Clinically diagnosed hemangioma, in proliferative or involutive phase, with relative indication for clinical treatment, as itemized lesion causing alteration of regional anatomy with no systemic or functional damage and with a diameter greater than 1 centimeter, or lesion causing aesthetic deformity, or lesion causing local repetitive complications such as ulceration, bleeding or local infection, or lesion causing partial damage of orifices, or lesion causing psychological compromise Absence of cardiopathy (normal physical examination, anamnesis, echocardiography, electrocardiography and thoracic radiography) Informed consent signed by responsible parties  Hemangioma with absolute indication for treatment, presenting a risk to function or life Patients with previous treatment for infantile hemangiomas Cardiac disease Pulmonary disease (asthma, bronchiolitis,bronchopulmonary dysplasias) Raynaud syndrome Pheochromocytoma Altered echocardiography, even if asymptomatic
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 11.0-999.0,  Acanthosis Nigricans Hyperinsulinemia Spectroscopic Analysis Subjects must have an elevated fasting insulin level, suggesting they are in an insulin resistant state Subjects must carry a diagnosis of acanthosis nigricans, which will be verified by a Dermatologist before entry into the study. If necessary, a small 4mm punch biopsy may be taken to document dermatopathology consistent with acanthosis nigricans Subjects must be willing and able to undergo treatment with Metformin, including initial referral and follow up Agree to abide by the investigator's guidelines Be able to understand the requirements of the study, the risks involved and are able to sign the informed consent form Agree to follow and undergo all study-related procedures  Subjects with Type 1 Diabetes are excluded because of their naturally insulin-deficient, rather than hyper-insulinemic, states Women who are lactating, pregnant, or planning to become pregnant Any reason the investigator feels the patient should not participate in the study
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Benign and Malignant Skin Neoplasms Patients with skin lesions undergoing biopsy for diagnosis  Patients with skin lesions which do not require biopsy for diagnosis
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 20.0-85.0,  Lymphadenopathy Malignancy Patients with malignant cervical lymphadenopathie With US-FNA or US-CNB evaluation before  No ultrasound exam
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Infant and Young Child Feeding Mothers with healthy children between 6 and 24 mo
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Colonic Polyp Patients with pedunculated colorectal polyps, the heads of which were larger than 10mm and the stalk of which were large than 5 mm in diameter, were included  bleeding tendency poor preparation sessile polyp
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Actinic Keratosis Male or female, age 18 years or older being seen in a dermatology clinic Informed consent of participation must be given by subject  Inability to complete all study questionnaires Subjects who are unable to read and write English
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 20.0-35.0,  Acne Vulgaris Have Acne vulgaris, presenting at least inflammatory lesion on the face Body mass index between 18.0 and 30.0 kg/m2 (inclusive), and body weight not less than 50 kg (man) or 45 kg (woman) Blood pressure between 90 and 140 mmHg systolic (inclusive), and no higher than 90 mmHg diastolic Electrocardiogram (ECG) consistent with normal cardiac conduction and function Non-smoker Adequate contraception method for both men and women. If a woman, must have a negative pregnancy test Signed an informed consent document  History of or current clinically significant medical illness that the investigator considers should the participant or that could interfere with the interpretation of the study results Clinically significant abnormal values for hematology, biochemistry or urinalysis Clinically significant abnormal physical examination, vital signs or ECG Use of any prescription or nonprescription medication within 14 days before the study treatment History of drug or alcohol abuse within the past 5 years Drug allergy or drug hypersensitivity Blood donation, depending on the volume of blood collection Positive test for human immunodeficiency virus (HIV), hepatitis B or C, or syphilis Dermatological disease at application site Photosensitivity
Patient description: A 43-year-old woman visits her dermatologist for lesions on her neck. On examination, multiple lesions are seen. Each lesion is small soft, and pedunculated. The largest lesion is about 4 mm in diameter. The color of different lesions varies from flesh colored to slightly hyperpigmented.

Clinical trial eligibility criteria: eligible ages (years): 21.0-999.0,  Venous Disease Venous Vascular Diseases and Syndromes Venous Insufficiency Venous Ulcers aged 21 years or older CEAP Classification: Stage C4 (skin damage) and 5 (healed VLU) leg ulcer healed within past month with intact epithelium history of healed VLU within past 2 years ankle brachial index (ABI) 0.80 3 mmHG, absence of peripheral arterial disease intact skin sensation intact thermal sensation agreement to ear compression during waking hours phone, email or mail accessible  diagnosed arterial disease or ABI <0.80 or >1.3 mm Hg (blood flow to the skin is reduced in arterial disease and cooling could cause tissue ischemia) surgical procedures on leg in past 1 year (can affect venous circulation/cause edema) open leg/foot ulcers recent leg infection within past month (increased inflammation) impaired cognitive status (cannot perform procedures) chronic inflammatory and vascular conditions where blood flow of the skin may be impacted such as Lupus erythematosus, lymphedema, Raynaud's, rheumatoid arthritis, scleroderma, end stage renal disease, chronic obstructive pulmonary disease, chronic regional pain syndrome, multiple sclerosis, hypersensitivity to cold, or patients on chemotherapy