semaj83/ctmatch_classification huggingface dataset:
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-64.0,  Depressive Disorder, Major Patients who meet the following will be included in the study aged 18 to 64 years diagnosis of major depressive disorder during the study timeframe (ICD 9 codes 296.2, 296.3, 311) evidence of at least 6 consecutive claims for traditional antidepressant therapy with a 30 day supply or at least 2 claims with a 90 day supply (consecutive defined as ≤15 days gap) must be continually enrolled during the study timeframe and have both medical and pharmacy benefits evidence of at least 4 consecutive claims for an atypical antipsychotic prescription with a 30 day supply or 2 claims with a 90 day supply (consecutive defined as ≤15 days gap) evidence of antidepressant therapy for at least 60 consecutive days prior to the initiation of atypical antipsychotic After at least a 60 day trial of traditional antidepressant medications, patient augments with an atypical antipsychotic medication for at least 4 months  Patients are excluded if they have any claims for a diagnosis of schizophrenia, schizoaffective or bipolar disorder during the study period have Electroconvulsive therapy (ECT) during the study period new augmentation with mood stabilizers, L-thyroxine (T4), L-Thyronine (T3), buspirone, stimulant, or others during the post-period (table 1) are pregnant during the study period patients with Medicare or Medicaid
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-90.0,  Major Depression A primary psychiatric diagnosis of Major Depressive Disorder as defined by: a score of 18 or above in the 17-item Hamilton Depression Scale; Male or female ages 18+ Ability to give consent Diagnosis of Breast Cancer Patients may be either English or Spanish speaking  Lifetime history of psychosis or bipolar disorder Patients meeting diagnostic statistic manual for mental disorder for alcohol or substance use disorders who require acute detoxification Current suicide risk Advanced cancer or other condition that limits remaining life expectancy to less than 6 months Patients who are receiving effective medication for Depression
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Depression h and 8th grade students at 4 participating middle schools Score 14 or above on the Mood and Feelings Questionnaire at screening (approximately top 25%) No imminent plans to move or change to non-participating school At minimum 6th grade language skills Agree to participate in random assignment and research interviews One Parent/caregiver willing to complete research interviews  Student with past or current Major Depressive Disorder (MDD) or Probable MDD Students with parents who do not speak English or Spanish Students in concurrent treatment Students in self-contained classroom, or with cognitive delays, or emotional behavioral problems that would preclude them from benefiting from the group or being a good group member Parent not willing to complete research interviews
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Insomnia Depression Clinical level of Insomnia (more than 10 on ISI) Meets for Insomnia according to DSM-IV-TR Enough language skills Only Trial 2: Meets for Major Depressive Disorder according to DSM-IV-TR  Sleep disorders requiring other treatment High consumption of alcohol/drugs that affect sleep Started to use or changed the dose of antidepressant drug during the last 2 months Somatic or psychiatric conditions requiring acute care Working night shifts Only Trial 1: Meets for Major Depressive Disorder according to DSM-IV-TR
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Depressive Disorder, Major ≥1 fill for an augmentation therapy medication from Table 1 during the identification period of 01 January 2005 November 2008 months of continuous enrollment with medical and pharmacy benefits each before the index date (pre-index period) and after the index date (post-index period) ≥1 medical claim with a primary International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) diagnosis for MDD (296.2x, 296.3x, 311.xx) during the pre-index period Age ≥18 years as of the year of the pre-index period  No pharmacy claims for atypical antipsychotics, mood stabilizers, anxiolytics, anticonvulsants, or stimulants, during the pre-index period No medical claims with primary or secondary diagnoses for non-MDD episodic mood disorders or schizophrenia during the pre-index or post-index periods
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Sleep Deprivation All subjects will be sedentary. Sedentary will be defined as those with an occupational calorie expenditure that is not estimated at greater than 50% above basal (desk job or light activity at work: on feet 30-50% of the work day) and whose exercise activity is defined as sedentary according to a self-reported activity questionnaire, and confirmed by actigraphy measurements. Sedentary lifestyle will be defined as fewer than four 20 min episodes of moderate or vigorous intensity activity in the previous four weeks  We will subjects who have any medical or psychiatric disorders, including history of anxiety or depression, and those taking any medications Those found to have depression on a depression screening tool (BDI-II) will be excluded Current smokers will be excluded All female subjects will undergoing a screening pregnancy test and excluded if positive Subjects found to have significant sleep disorders will be excluded. - Subjects found to have occult coronary artery disease by exercise treadmill testing will be excluded
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Major Depressive Disorder DSM-IV for major depressive disorder Age being age 18-65 Capacity and willingness to give written informed consent  Any major medical illnesses A recent or past history of any Axis-I diagnoses besides major depressive disorder, including psychotic disorders; cognitively impaired mental disorders; impulse control disorders; substance use disorder or substance abuse (last 6 months prior to the studies); primary anxiety disorders, including post-traumatic stress disorder and panic disorder; and bipolar disorders; or Axis-II diagnoses, i.e. borderline and antisocial personality disorder
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Advanced Cancers Solid Tumors All patients with a histological diagnosis of cancer Rate fatigue on a numerical scale during the previous 24 hours as >/= 4 on a 0 to 10 scale (0 = no fatigue and 10 = worst possible fatigue) Describe fatigue as being present every day for most of the day for a minimum of 2 weeks Memorial delirium assessment scale </= 13 Are 18 years or older Hemoglobin level of >/=8 g/dL within 2 weeks of enrollment. If the patient has not had blood drawn for a hemoglobin level in the previous two weeks, one will be performed to determine eligibility. Patients with a hemoglobin level <9g/dL will be evaluated for treatment of anemia Able to understand and sign the informed consent No concurrent use of chronic systemic steroids (defined as currently on more than 1 week of treatment) Controlled pain and depression symptoms, if present ( defined as no change in the Morphine equivalent dose of 30% or change in the dose of antidepressant medication in the past 2 weeks) Patients should have a Zubrod </= 2  Major contraindication to ginseng: allergy/hypersensitivity to Panax species or their constituents (history of arrhythmias, agitation, or motor tics, or severe angina pectoris) Currently taking ginseng, methylphenidate or modafinil or have taken it within the previous 10 days Inability to complete the baseline assessment forms or to understand the recommendations for participation in the study Currently with a diagnosis of major depression, manic depressive disorder, obsessive-compulsive disorder, or schizophrenia) Symptomatic tachycardia and uncontrolled hypertension (determined to be clinically significant by the PI) Currently receiving phenobarbital, diphenylhydantoin, primidone, phenylbutazone, MAOIs, clonidine and tricyclic antidepressant drugs Uncontrolled diabetes mellitus as defined by a random blood sugar of >200mg/dl not being monitored by their primary care physician No concurrent full dose anticoagulant therapy. </= 1 mg/day of coumadin for preventing catheter clots allowed History of hepatitis A, B and C Women who are nursing
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Depression Participants must have a score ≥ 10 on the self-report Patient Health Questionnaire (PHQ-8), indicative of clinically significant, moderate depression Participants must identify their primary healthcare provider in one of the 8 performance sites, and give permission to contact him or her for the purpose of periodic progress reports as well as a referral contact in case any emergent crises are detected Participant must be 18 years of age have access to a computer with internet and a working email address Participants must also indicate they are planning to continue receiving services from one of the performance site clinics/organizations for at least the next 6 months
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 21.0-65.0,  Major Depressive Disorder age 21-65 years including males, females and minorities diagnosis of DSM-IV major depression or Bipolar I or II with current episode of depression HDRS-17 > 20 and HDRS-24 > 24 negative pregnancy test for women of childbearing potential not breast feeding stable on current dose of psychotropic medication or free from all psychotropic medications for 4 weeks prior to EUH CIN admission (8 weeks for fluoxetine) no suicide attempt within six months of screening  evidence of untreated or poorly controlled endocrine, cardiovascular, pulmonary, hematological, renal, or neurological disease history of CNS trauma or active seizure disorder requiring medication unless otherwise approved by principle investigator autoimmune or inflammatory disorder of any kind chronic infection (e.g. hepatitis B or C or HIV) chronic use of agents known to affect the immune system including glucocorticoid therapy within the past 1 year, methotrexate within the past 1 year, chemotherapy of any kind (past or present), immunotherapy of any kind (past or present), aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) (within the past 2 weeks) and statins (within the past 1 month) unless otherwise approved by principle investigator hemoglobinopathies (e.g. thalassemia) a positive pregnancy test organ transplants cancer of any type a score of <28 on the Mini Mental Status Exam (MMSE)unless otherwise approved by principle investigator
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Borderline Personality Disorder Major Depression age between 18 and 45 female noncontrols diagnosis: major depression &/or borderline personality disorder Control participants should have neither major depression or borderline pers meet Structured Controlled Interview for DSM II cut off scores meet Beck Depression Inventory (BDI)cut off scores meet Borderline Evaluation of Severity Over Time(BEST) cut off scores  based on having none of the below diagnoses from patient history, prior clinical records and based on MINI Plus International Neuropsychiatry Interview schizophrenia psychosis Attention Deficit Hyperactivity Disorder Obsessive Compulsive Disorder bipolar disorder mental retardation dementia CNS disease Post-Traumatic Stress Disorder in non-borderline personality disorder groups
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 20.0-999.0,  Depressive Disorder, Major Age over 20 years DSM-IV episode of MDD non-psychotic with atypical features characterized by mood reactivity and 2 or more symptoms of vegetative reversal (including overeating, oversleeping, severe fatigue or leaden paralysis, and a history of rejection sensitivity) More than 19 score on the 29-item HAM-D Ability to give informed consent  Bipolar depression Any Axis I psychotic disorder A history of suicide attempt, self-injurious action (excluding action with no intention of suicide) or overdosage (excluding apparently accidental overdosage) Patients with more than 3-point score of suicide (HAM-D-29 Item 18) or patients whose C-SSRS assessment suggests that they are or have been at significant risk for harming themselves or have actually harmed themselves, or who, in the opinion of the investigator (sub-investigator), are at significant risk for harming self or others A history of substance abuse in the previous 12 months A history of hypersensitivity to bupropion or any other components of the preparations used in the study (Wellbutrin SR 150mg and Wellbutrin XL 300 mg tablets) Serious or unstable medical disorders Starting or terminating psychotherapy during the previous 12 weeks ECT treatment in the previous 3 months Subject has a life time diagnosis of anorexia nervosa or bulimia within the past 12 month
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-55.0,  Major Depressive Disorder Outpatients who met Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) for major depressive disorder Those who are in remission, which is defined as a MADRS score 8 on two consecutive visits at a 4-week interval Their primary psychiatric clinician determined that they would benefit from an adjuvant treatment of Korean red ginseng for residual symptoms  Those who have a history of substance abuse or dependence within 1 month Those who have clinically significant abnormal laboratory values or any other abnormal baseline laboratory findings considered by psychiatrists to be indicative of conditions that might affect the study results Those who have a past history of hypersensitivity or intolerance to Korean red ginseng Those who participated in clinical trials within 1 month before entering the study entry Those who are pregnant or are breast feeding Those who have a immediate risk of harming self or others or history of suicide attempts in the year before the screening precluded in the study The patients unable/unlikely to comprehend/follow the protocol
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Fatigue Traumatic Brain Injury mTBI GROUP Diagnosis of at least one mTBI during deployment At least six months from time of injury Age range 18 or older A self-report of somatic or behavioral symptoms that developed within 3 months following mTBI and were not present before injury, and may or may not be present at enrollment Easy fatiguability Sleep disturbance Headache or other chronic widespread pain that does not seem related to extremity injury Emotional lability Lack of spontaneity or apathy  mTBI GROUP Daily use of stimulants, narcotics, hypnotic or anxiolytics Diagnosis of sleep apnea, thyroid disorder, or rheumatoid arthritis Any history of head injury associated with a loss of consciousness that lasted longer than 24 hours (not including sedation) Daily use of more than 600mg caffeine (equivalent to approximately five cups of coffee) Headaches more than once a month prior to deployment Pregnancy Claustrophia Inability to comfortably lie supine for two hours companion group
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  MDD Management Strategies MDD Diagnosis Participants of the PismaEP study 18 yo. or older  No specific