semaj83/ctmatch_classification huggingface dataset:
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 12.0-999.0,  Bipolar Disorder Age greater than or equal to 12 years Able to give basic informed consent Meets DSM-IV for Bipolar I, Bipolar II (if in the investigator's judgment long term treatment with a mood stabilizer is indicated), Bipolar NOS, or Schizoaffective Bipolar subtype Because many adolescents have shorter periods of mania or hypomania than those required by the DSM-IV (at least 4 days for hypomania and 7 days for mania) adolescents are included who have a current episode of MDD and a history of episodes mania/hypomania that lasted for at least 2 days  Unwilling or unable to comply with study requirements (e.g., complete study forms, attend scheduled evaluations) Not competent to provide informed consent in the opinion of the investigator Mental retardation (IQ less than 70). Subjects suspected of mental retardation (e.g., chronic academic failure, multiple developmental delays) are evaluated using the Verbal Subtest of the Wechsler Intelligence test Presence of schizophrenia, schizoaffective pervasive developmental disorder, current substance or alcohol dependence, and organic mental disorder. Substance dependence in early remission is not an criterion Unstable medical illness or other medical contraindication to treatment with mood stabilizers, antidepressants or antipsychotic medications Women who are planning to become pregnant, pregnant or breast-feeding
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-70.0,  Bipolar Disorder Alcohol Dependence English or Spanish-speaking Age 18-70 Diagnosis of bipolar I or II Current mood state of depressed or mixed Alcohol use of at least 5 drinks in the past 7 days Current diagnosis of alcohol dependence  Bipolar disorders other than bipolar I or II disorders (e.g., bipolar NOS, or cyclothymic disorders, schizophrenia, schizoaffective disorder, or unipolar) Lifetime opiate abuse or dependence or any current use (including prescription drugs) Diagnosis of current dependence on substances other than alcohol (participants with only abuse of other substances are included. Dependence on caffeine and/or nicotine is allowed.) Severe or life-threatening medical illness (e.g., hepatic cirrhosis, congestive heart failure, terminal cancer) or labs consistent with serious medical illness (e.g., severe edema, atrial fibrillation, dangerously abnormal electrolytes) Pregnant or nursing female High risk for suicide defined as ≥2 suicide attempts in the past 12 months that required medical attention, or current suicidal ideation with plan and intent Prior therapy with naltrexone and/or allergic reaction to naltrexone Current therapy with acamprosate or disulfiram Member of a vulnerable population (Dementia, cognitively impaired, mental retardation, prisoner) Baseline YMRS or HRSD17 scores ≥ 30
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 21.0-65.0,  Depression Diagnosis of recurrent major depression  Unstable medical illness Any other simultaneous psychiatric or medical illness of greater concern than depression (index episode of depression is not primary)
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Bipolar Disorder Diagnosis of bipolar disorder Currently in the third episode of mania or major depression History of one other episode of major depression within 5 years prior to study entry  Currently in the first episode of mania or schizo-affective disorder (manic type) Rapid cycling drug or alcohol abuse Unstable medical illness Pregnant Index episode caused by medically prescribed drugs
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 20.0-60.0,  Fibromyalgia Posttraumatic Stress Disorder Major Depressive Disorder Healthy volunteers without any current or past psychiatric disorder Current diagnosis of PTSD Current diagnosis of MDD  Psychotic features
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Breast Cancer Major Depressive Disorder Women aged 18 years or older Diagnosis of breast cancer, confirmed by histopathology; Stages 0, I, II, IIIA, or IIIB Clinical diagnosis of Major Depressive Disorder (DSM-IV-TR) Hospital Anxiety and Depression Scale (Zigmond and Snaith, 1983) depression subscale score of 11 or greater Montgomery Asberg Depression Rating Scale (MADRS; Montgomery and Asberg, 1979) score of 25 or greater at Screening and Baseline visits Use of antidepressants in a previous episode of major depression or in the past for any other indication does not affect the patient's in this study During the current episode of major depressive disorder, as stated in the failure to respond to one or more adequate trials of an antidepressant will the patient from the study since this is not a study of "treatment-resistant depression" During the study, the patient may not use any other antidepressants  Presence of another current clinically significant Axis I disorder like bipolar disorder, schizophrenia, or panic disorder Current (in past 6 months) comorbid active substance abuse or dependence Failure to respond to one or more adequate trials of an antidepressant in the current episode of MDD A reduction in MADRS score of 20% or greater from Screening to Baseline visit Clinically significant laboratory abnormalities that in the judgment of the Investigator would increase risk of adverse effects with bupropion Pregnant or lactating women History of an eating disorder, seizures, head injury, or other intracranial pathology because these conditions are usually contraindications to the use of bupropion XL Previous allergy or intolerance to bupropion Patients judged to be at significant suicidal risk
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 21.0-70.0,  Depression History of recurrent major depression Has a parent or sibling with a history of recurrent major depression Depression began before the age of 31  Bipolar I (manic-depressive) disorder Schizophrenia
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Depression Less than 24 weeks pregnant at the time of study entry As of 12/1/2005, at significant risk for developing depression or currently taking SSRIs during pregnancy  History of or current psychosis, bipolar disorder, or schizoaffective disorder Current substance use disorder Any medical condition that may be related to outcomes (such as multiple births or insulin-dependent diabetes) Has not attended at least two prenatal visits at the 20-week intake point
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Depression 6 weeks postpartum English-speaking Score of at least 10 on the Edinburgh Postnatal Depression Scale  DSM-IV diagnosis of bipolar disorder or psychotic episode Active substance abuse within 6 months prior to study entry Has not received obstetrical care History of a suicide attempt within 6 months of study entry
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  HIV Infections Depression Available for at least 9 months, or the duration of the study Willing to complete HIV testing and counseling History of HIV testing and counseling At high risk of HIV infection, indicated by more than one male sexual partner in the 3 months prior to study entry Meets for either (a) major depression or dysthymia within a mild-to-moderate level according to standard DSM-IV, or (b) minor depression as defined by one or more of the following symptoms at any time and for any duration during the past 12 months: significant weight loss or gain, or significant decrease or increase in appetite; poor sleep pattern; noticeable irritability or slowness; fatigue or lack of energy; inappropriate feelings of worthlessness or guilt; inability to concentrate; indecisiveness; and recurrent thoughts of death or suicide  HIV infected Sexual intercourse in the 3 months prior to study entry with only one partner, and in a monogamous relationship Currently enrolled in another study involving repeated HIV testing and counseling Receiving treatment for depression with antidepressant medication for any length of time within the year prior to study entry Currently in psychotherapy, psychoanalysis, or any other form of talk therapy for any reason Severe depression or at suicidal risk No evidence or prior history of depression Homicidal or other similar problem that, in the opinion of the investigator, may endanger study staff and participants Currently taking monoamine oxidase inhibitors (MAOIs). Participants may be allowed to enroll 14 days after discontinuing use of a MAOI History of seizures
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Major Depression Participants must present with a first or new episode of DSM IV non-psychotic major depression warranting treatment with antidepressant mediation Must be able to give informed consent  History of psychosis or mania/hypomania or personality disorder Non-English speaking or otherwise unable to provide historical information Having taken Omega-3 dietary supplements in the last 3 months History of allergy to Omega-3 supplements, finfish or shellfish Pregnancy, breast feeding or plans to become pregnant during course of study Post-natal depression Current drug or alcohol abuse or dependence or history of abuse or dependence over the last 12 months Unstable thyroid function Hepatic or renal impairment or other medical conditions that may interfere with the absorption and metabolism of Omega-3 polyunsaturated fatty acids Coagulopathy or anticoagulant treatment due to theoretical bleeding risk
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Depression Between 8 and 32 weeks of gestation at time of study entry A score above 12 on the Edinburgh Postnatal Depression Scale Speaks English Resides in the Pittsburgh, PA, area Access to a household telephone  Currently receiving treatment for depression (i.e., medication or psychotherapy) History of a prior manic episode Alcohol or drug abuse or dependence within 6 months of study entry Psychotic disorder or organic mental disorder Suicidal, homicidal, or requires hospitalization Severe sexual and/or physical aggression in relationship with partner or husband Significant medical illness such as epilepsy, autoimmune disorder, liver dysfunction, or unstable endocrine disease Severe cognitive deficits that would prevent treatment with psychotherapy
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-50.0,  Depression Major Depressive Disorder Males and Females Age: 18-50 Recurrent Major Depressive Disorder; current Major Depressive Episode with at least one prior episode HAM-D >16 Able to give written informed consent Agree to use a reliable means of birth control during the study, as determined by the investigator (females of child-bearing potential only)  History of head injury or loss of consciousness for longer than 30 minutes Presence of primary anxiety disorder, bipolar I or II disorder, or psychotic disorders Presence of anorexia nervosa or bulimia nervosa Presence or history of epilepsy or other seizure disorders Presence of significant Axis II disorder based on investigator judgment Presence of significant unstable medical condition Presence or past history of ADHD or significant learning disability ECTs (unilateral) within the past 12 months or bilateral ECT (ever) More than 2 failed adequate antidepressant treatments in the current episode Pregnant or breast-feeding females
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Depressive Disorder, Major A primary diagnosis of MDD Depressive symptoms for at least 30 days before the screening visit  Treatment with DVS SR at any time in the past Known hypersensitivity to venlafaxine Significant risk of suicide based on clinical judgment