semaj83/ctmatch_classification huggingface dataset:
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 21.0-45.0,  Lactation Bone Diseases, Endocrine Group 1: Post-partum (singleton pregnancy) African-American women who are exclusively breastfeeding, defined as 1 or fewer bottles of supplemental formula/day Group 2: Post-partum (singleton pregnancy) African-American women are non-lactating, which is defined as bottle-feeding or having weaned their baby from breastfeeding for at least 4 weeks prior to study Group 3: Controls Healthy non-pregnant African-American women will be race and age-matched to the breast-feeding women in group one. They may not have been lactating or pregnant within the last year  Subjects with cardiac, hypertensive, vascular, renal (serum creatinine of >1.5), pulmonary, endocrine, musculoskeletal, hepatic, hematologic or malignant or rheumatologic disease will be excluded from the study Smokers and those with a history of significant alcohol or drug abuse are excluded Baseline hypertension (systolic BP > 160 mm/Hg) or hypotension (systolic BP < 90 mm/Hg) Subjects taking any chronic medications except stable doses of thyroid hormone, prenatal, vitamin supplements, or oral contraceptives Those who have received any investigational drug in past 90 days will be excluded from the study Women who are currently pregnant will be excluded from the study. Women who became pregnant by In Vitro Fertilization IVF or any hormonal manipulation (i.e. fertility drugs such as clomid ®) are also excluded, as they may have an altered pre-pregnant hormonal state. All women will have a urine pregnancy test performed at each of the two study visits and must not be pregnant in order to continue in the study. Subjects are not allowed to donate blood between study visits
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Asthma Eczema Allergy (mother) Pregnant women Living in Sealand, Denmark Fluent in Danish Language Willing to let the newborn child participate in the study  (mother) Participating in other clinical trial
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 16.0-50.0,  Bacterial Vaginosis Women will be included whether their complaint is symptoms of BV and have a positive whiff test/vaginal swab or if they have a positive whiff test/vaginal swab and are then asked if they have any symptoms of BV present. The following must be met for enrolment in the study: 1. ages 16-50 and premenopausal; 2. capable of giving written informed consent; 3. English speaking; 4. negative pregnancy test on enrolment day; 5. agree to follow study protocol; 6. documented BV infection by positive vaginal swab +/ positive whiff test/pH > 4.5; 7. agree to no intercourse for the 10 days of treatment (or to use non-lubricated condoms if unavoidable); 8. agree not to douche or use any intravaginal products during treatment (including tampons, medications, devices); 9. abstain from alcohol during the 10 days of treatment (from 24 hours before through 72 hours after taking study medication); 10. agree to no new medications or antibiotics during treatment; 11. no current sexually transmitted infection as determined by history, physical exam and negative swabs for chlamydia, gonorrhea, candidiasis, trichomonas; 12. patient is reliable for follow up  The following women would be excluded from study participation: 1. less than 16 or post-menopausal; 2. negative vaginal swab regardless of whiff test/pH > 4.5; 3. menstruating at diagnosis; 4. symptoms so severe as to make allocation to placebo unacceptable to the patient; 5. currently pregnant or at high risk for pregnancy; 6. current sexually transmitted infection (HIV, hepatitis, chlamydia, gonorrhea, trichomonas, HPV or HSV); 7. current yeast infection as determined by history, physical and swabs; 8. history of PID; 9. allergy to latex or metronidazole; 10. presently lactating; 11. any open wound, excoriation, vaginal irritation and including bartholin's cyst/abscess as determined by physical exam; 12. presence of another vulvar, vaginal or medical condition, including cervical neoplasia treatment, that might confound treatment response; 13. using lithium, anti-coagulants or disulfiram drugs; 14. any antifungal or antibiotic use 14 days prior to enrolment 15. PAP smear done within one week of enrollment
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 18.0-50.0,  Norovirus Signed written informed consent 2. Age 18 years, inclusive 3. Good general health as determined by a screening evaluation within 30 days before administration of Norwalk VLP Vaccine, adjuvant/excipients or placebo 4. Expressed interest and availability to fulfill the study requirements 5. Agrees not to become pregnant from the time of study enrollment until at least 56 days after the last administration of Norwalk VLP Vaccine, adjuvant/excipients or placebo; if a woman is sexually active and capable of conception (i.e., no history of hysterectomy or tubal ligation), she must agree to use hormonal or barrier birth control. A woman is eligible if she is monogamous with a male who has had a vasectomy. 6. Demonstrated to be an H type-1 antigen secretor 7. Agrees not to participate in another clinical trial with an investigational product for the entire duration of the study (six months after the last study dose i.e. 201 days) 8. Agrees to storage of unused clinical specimens for an indefinite period of time only for those specimens collected by the University of Maryland CVD for use in future research at the CVD. [A University of Maryland site-specific criterion]  History of any of the following medical illnesses Chronic rhinitis, runny nose, sneezing Clinically significant nose bleed within the last year Diabetes Cancer Heart disease (hospitalization for a heart attack, arrhythmia, or syncope) Unconsciousness (other than a single brief "concussion") Seizures (other than febrile seizures as a child <5 years old) Recurrent infections (more than 3 hospitalizations for invasive bacterial infections such as pneumonia or meningitis) Asthma requiring treatment with inhaler or medication
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 0.5-999.0,  Influenza Unvaccinated patients presenting to the Emergency Department aged 6 months or more who have at least one high risk attribute Age 6-59 months or >50 years Pregnant Health care worker Aged 6 months-18 years on chronic aspirin therapy Comorbidity (cardiovascular disease, pulmonary disease, metabolic disease, renal disease, hepatic disease, seizures, neuromuscular disease, cognitive dysfunction, or any reason to have had regular medical follow up or hospitalization in the preceding year) Household contact or caregiver of someone with at least one high risk attribute  Prior vaccination History of Guillan-Barre syndrome within 6 weeks of prior influenza vaccination Allergy to influenza vaccination or eggs Age < 6 months old Fever with more than minor illness Hospitalization
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Human Papillomavirus Infection Female partners of HIM Study participants report no abnormal Pap smear during the past 6 months have not had a hysterectomy have never been diagnosed with genital warts are not pregnant residents of southern Florida are not and have not been enrolled in an HPV vaccine trial willing to comply with scheduled visits every 6 months for 2 years  Do not meet the Criteria
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Stress Healthy first-time mothers with singleton baby delivered at term with no complications  Mothers with chronic health problems Pregnancy complications, OR Infants with congenital problems or conditions requiring admission to the intensive care nursery
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 20.0-45.0,  Premenstrual Syndrome Person is over the age of 20 but not older than age 45. 2. Person is willing to participate as evidenced by signing the written informed consent form. 3. Suffers from known dominant severe symptom of breast swelling and tenderness (level 7-10 according to standard scale of PMS symptoms severity) 4. Other severe symptoms of Premenstrual syndrome (based on WHO and ACOG criteria). This may one or more of PMS symptoms with level 7-10 according to standard scale of PMS symptoms severity. 5. At work, school, home, or in daily routine, at least one of the PMS symptoms caused reduction of productivity or inefficiency 6. At least one of the PMS symptoms caused avoidance of or less participation in hobbies or social activities 7. At least one of the PMS symptoms interfere with relationships with others: i. Timing of PMS symptom(s): during the 14 days prior to onset of menstrual flow (rather than spotting) and up to 5 days during the menstrual flow. ii. Pattern and length of PMS symptomatic period: minimum of 2 days, up to 14 days. iii. For PMS diagnosis two out of last three consecutive menstrual cycles were monitored by daily monitoring of symptoms. iv. Timing and length of asymptomatic phase: day 6 to at least day 10 of the menstrual cycle. v. Cyclicity presentation of the 'off-on' phenomenon: there should be a clear shift from no PMS symptoms to PMS symptoms. vi. Reliable non hormonal contraception  Pregnant or lactating woman 2. Oral contraceptives during last three months, including hormonal IUD (trade name mirena). 3. Serious health problems. 4. Unexplained menstrual disorders. 5. Treated by hormones (estrogen and progesterone). 6. For healthy: Irregular or abnormal test results
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 19.0-50.0,  Influenza Healthy Healthy volunteers (as concluded from the medical history, physical examination, and clinical judgment) aged 19 to 50 years old Females using a reliable method of contraception (from 4 weeks prior to the first vaccination until 4 weeks after the second vaccination) and a negative urine pregnancy test will be required before administration of each dose of vaccine Signed informed consent Subjects able to understand and comply with the study protocol and complete the Adverse Event Form Subjects able to attend the scheduled visits Subjects with normal pre-screening values. If a subjects prescreening samples lie outside the reference values he/she will only be included in the study based upon the medical evaluation of the clinical investigator  Persons with a history of anaphylaxis or serious reactions to any vaccine Persons with known hypersensitivity to any of the vaccine components Persons who have had a temperature >38oC during the previous 72 hours Persons who have had an acute respiratory infection during the last 7 days Women who are pregnant or breast-feeding Persons with chronic illness at any stage that could interfere with trial conduct or compliance Persons who have received blood products or immunoglobulins parenterally during the previous 3 months Persons who have been vaccinated with any vaccine during the 4 weeks preceding the first trial vaccination Persons with known or suspected immunosuppressive disease or who use systemic immunosuppressive drugs Persons taking immunostimulant therapy
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 18.0-49.0,  Healthy Healthy males and females between 18 and 55 years (inclusive) of age Non-smoking (by declaration) for a period of at least 6 months Subjects able to adhere to the visit schedule and protocol requirements and be available to complete the study Haematology and Chemistry values within normal ranges or with no clinical significance Subjects who provide written informed consent to participate in the study  Known history of significant medical disorder, which in the investigator's judgment contraindicates administration of the study medications Ongoing flu symptoms or influenza Any clinically significant abnormality upon physical examination or in the clinical laboratory test at screening visit Treatment with immune immunosuppressant drugs or other immune enhancing drugs Subjects who have been immunized with anti-influenza vaccine or infected by influenza virus within one year prior to the screening visit Administration of any vaccine 30 days before the screening visit Known history of drug or alcohol abuse Known history of HIV, hepatitis C or B virus (HCV or HBV) Subjects with known Guillain Barré Syndrome in the past or more hospitalization within the last year prior to screening visit
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 18.0-59.0,  Influenza Avian Influenza Male and female subjects will be eligible for participation in this study if they are 18 to 59 years of age, inclusive, on the day of screening have an understanding of the study and its procedures, agree to its provisions, and give written informed consent prior to study entry are generally healthy, as determined by the investigator's clinical judgment through collection of medical history and performance of a physical examination are physically and mentally capable of participating in the study and follow its procedures agree to keep a daily record of symptoms for the duration of the study if female of childbearing potential: have a negative urine pregnancy test result within 24 hours prior to the scheduled first vaccination and agree to employ adequate birth control measures for the duration of the study  Subjects will be excluded from participation in this study if they have a history of exposure to H5N1 virus or a history of vaccination with an H5N1 influenza vaccine are at high risk of contracting H5N1 influenza infection (e.g. poultry workers) currently have or have a history of a significant neurological, cardiovascular, pulmonary (including asthma), hepatic, metabolic, rheumatic, autoimmune, hematological or renal disorder have any inherited or acquired immunodeficiency have a disease or are currently undergoing a form of treatment or were undergoing a form of treatment within 30 days prior to study entry that can be expected to influence immune response. Such treatment includes, but is not limited to, systemic or high dose inhaled (> 800µg/day of beclomethasone dipropionate or equivalent) corticosteroids, radiation treatment or other immunosuppressive or cytotoxic drugs have a history of severe allergic reactions or anaphylaxis have a rash, dermatological condition or tattoos which may interfere with injection site reaction rating have received any blood products or immunoglobulins within 90 days prior to study entry have donated blood or plasma within 30 days prior to study entry
Patient description: A 42-year-old healthy woman came to the clinic to have her flu shot in early October. She works in a rehab center and has no underlying disease. It's her first time getting the vaccine this year. She is married for 5 years and uses barrier methods of contraception. Her menstrual cycle is irregular. She does not smoke. She is not on any medications. She exercises regularly for 30 minutes a day at least 5 days a week. She has no history of allergies to any food or drugs. Her past surgical history is significant for tonsillectomy and she is otherwise healthy.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Contraception Requiring contraception Normal cervical smear Maximum age for smokers is 35 History of regular cyclic menstrual periods  Pregnancy or lactation Significant skin reaction to transdermal preparations or sensitivity to surgical / medical tape Any disease that may worsen under hormonal treatment (cardiovascular, liver, metabolic) Use of other contraceptive methods than study medication