semaj83/ctmatch_classification huggingface dataset:
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Biceps Tendon Rupture male subjects between 18 and 65 years of age patient has had a DBTR amenable to surgical repair surgeon must be able to obtain a tension-free repair using an endobutton participants must have been working prior to the injury patient must be expected to return to work post-injury  females outside of the specified age range patient with an identified congenital abnormality at the insertion of the distal biceps tendon those who have previously ruptured the tendon or those with tendon ruptures resulting from a multi-trauma patients with psychiatric illness, cognitive impairment, or health conditions that preclude informed consent patients with life expectancy of less than 2 years patients who do not speak/read/understand English patients with no fixed address or contact information patients who are unwilling to complete follow-ups
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Stroke Atrial Fibrillation (AF) Intracerebral Haemorrhage (ICH) Study I: (AF) Adult (≥18y; no upper limit) patients with a clinical diagnosis of non-valvular AF (verified by ECG) with intention to treat with best practice oral anticoagulants (e.g. warfarin) Previous ischaemic stroke or TIA diagnosed by treating clinician All patients must be able to have GRE MRI before (or within 1 week) of starting best practice oral anticoagulant  Any MRI contraindications Previous use of oral anticoagulation Definite contra-indication to oral anticoagulation Serious head injury (resulting to loss of consciousness) Study II: (ICH) • Adult (>18y) patients treated at participating centres with confirmed ICH (confirmed on CT or MRI scans) with or without a history of anticoagulant use at the time of the ICH Known underlying structural cause for ICH (e.g arteriovenous malformation, tumour, cavernoma, intracranial aneurysm, haemorrhagic transformation of an infarct) Major head trauma (causing loss of consciousness and though to be sufficient to have caused the ICH) in previous 24 hours
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Cardiac Arrest Sudden Death -Eligible patients have the following combination of Adults over 18 years of age and under 65 years of age And Refractory cardiac arrest (defined by the failure of professionals to resuscitate at the 20th minute of cardiac arrest with a minimum of 3 Automatic External Defibrillator (AED) or equivalent analyze And Beginning of external cardiac massage within the first 5 minutes after cardiac arrest (no flow < 5 min.) with shockable rhythm or the presence of signs of life during resuscitation (any rhythm): spontaneous movement, absence of mydriasis and/or pupillary response, respiration And Medical cause of the cardiac arrest And End-Tidal CO2 (ETCO2) above 10 mm Hg at the time of And Absence of major co-morbidity. And Extra-corporeal Membrane Oxygenation (ECMO) team available  Children under 18 years of age Adults over 65 years of age Period of more than 5 minutes without cardiac massage after collapsing Known co-morbidity that compromises the prognosis for short or medium-term survival Cardiac arrest during transportation times
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Primary Myelofibrosis Intermediate-1, intermediate-2, or high-risk PMF, PPV-MF or PET-MF as based on The Dynamic International Prognostic Scoring System (DIPSS) Palpable splenomegaly ≥5 cm below the LCM in midclavicular line by physical examination TSS ≥13 on the MPN-SAF TSS 2.0, not including the inactivity question, based on a single assessment during screening visit Age ≥18 years old at the time of screening (or minimum age of legal consent consistent with local regulations, if minimum is >18 years of age) ECOG performance status 0 to 3 Peripheral blast count <10% Absolute neutrophil count >500/μL Participants who are platelet or RBC transfusion dependent are eligible Adequate liver and renal function, defined by liver transaminases (AST/serum glutamic oxaloacetic transaminase [SOOT] and alanine aminotransferase [ALT]/serum glutamic pyruvic transaminase [SGPT]) ≤3 × upper limit of normal ([ULN], AST/ALT ≤5 × ULN if transaminase elevation is related to MF), direct bilirubin ≤4 × ULN, and creatinine ≤2.5 mg/dL At least 6 months from prior splenic irradiation  Any GI or metabolic condition that could interfere with absorption of oral medication Life expectancy <6 months Prior treatment with a JAK2 inhibitor Completed ASCT, or are eligible for and willing to complete ASCT History of splenectomy or planning to undergo splenectomy Uncontrolled intercurrent illness, including but not limited to ongoing active infection, or psychiatric illness, or social situation that, in the judgment of the treating physician, would limit compliance with study requirements Other malignancy within the last 3 years, other than curatively treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix, organ confined, or treated non-metastatic prostate cancer with negative prostate specific antigen, in situ breast carcinoma after complete surgical resection, or superficial transitional cell bladder carcinoma Inflammatory or chronic functional bowel disorder, such as Crohn's disease, inflammatory bowel disease, chronic diarrhea, or constipation Clinically symptomatic and uncontrolled cardiovascular disease History of any of the following within 6 months prior to first dose of pacritinib: myocardial infarction, severe/unstable angina, or symptomatic congestive heart failure
Patient description: A 33-year-old male athlete presented to the ER with acute abdominal pain. Family member says the patient fell off his bike a week earlier and suffered blunt trauma to the left hemi-abdomen, and he has had mild abdominal pain since that day. The patient's history is negative for smoking, drugs, and alcohol. BP: 60/30 mmHg, HR: 140/min. The patient is pale, the physical examination of the abdomen revealed muscle contraction and resistance. Emergency ultrasound and CT scan of the abdomen reveal extended intraperitoneal hemorrhage due to spleen rupture.

Clinical trial eligibility criteria: eligible ages (years): 7.0-18.0,  Appendicitis Children and adolescents aged 7-18 years old ASA Score I (American Society of Anesthesiologists classification) [Appendix 1]: a normal healthy patient ASA Score II (American Society of Anesthesiologists classification): A patient with mild systemic disease Patients scheduled for laparoscopic appendectomy surgery Uncomplicated appendicitis Hemodynamically stable patient No evidence of appendiceal perforation based on preoperative clinical and imaging assessment Diagnosed to have simple acute appendicitis by intraoperative laparoscopy Patients who have provided a written informed assent Caregivers who have provided a written informed consent  ASA Score III (American Society of Anesthesiologists classification): A patient with severe systemic disease ASA Score IV (American Society of Anesthesiologists classification): A patient with severe systemic disease that is a constant threat to life ASA Score V (American Society of Anesthesiologists classification): A moribund patient who is not expected to survive without the operation Hemodynamically unstable patient Evidence of appendiceal perforation on based on preoperative clinical and imaging assessment Perforated or gangrenous appendicitis diagnosed during laparoscopic surgery Postoperative admission in an intensive care unit with sedation or ventilatory assistance Cognitive impairment or mental retardation Progressive degenerative diseases of the CNS Seizures or chronic therapy with antiepileptic drugs
Patient description: An 8-year-old boy fell from his bike striking his left temple on the pavement. There was no immediate loss of consciousness, and a brief examination at the scene noted his pupils were symmetrical, reactive to the light, and he was moving all four limbs. Half an hour after the fall the child became drowsy, pale, and vomited. He was transferred to the emergency department. Upon arrival the heart rate was 52/min, blood pressure of 155/98. The Glasgow Coma Scale (GCS) was 6/15, the pupils were asymmetrical and movement of the right upper and lower extremities was impaired. The neurosurgical team advised deferring the CT scan in favor of initiating immediate treatment.

Clinical trial eligibility criteria: eligible ages (years): 6.0-16.0,  Brain Injuries Moderate to severe traumatic brain injury
Patient description: An 8-year-old boy fell from his bike striking his left temple on the pavement. There was no immediate loss of consciousness, and a brief examination at the scene noted his pupils were symmetrical, reactive to the light, and he was moving all four limbs. Half an hour after the fall the child became drowsy, pale, and vomited. He was transferred to the emergency department. Upon arrival the heart rate was 52/min, blood pressure of 155/98. The Glasgow Coma Scale (GCS) was 6/15, the pupils were asymmetrical and movement of the right upper and lower extremities was impaired. The neurosurgical team advised deferring the CT scan in favor of initiating immediate treatment.

Clinical trial eligibility criteria: eligible ages (years): 16.0-45.0,  Brain Injuries Hypothermia FOR EARLY TO 35°C GCS 3-8 on initial evaluation or deteriorates during transport Mechanism of injury consistent with blunt, non-penetrating trauma to head Systolic blood pressure > 110 mm Hg Diastolic blood pressure> 60 mm Hg Heart rate (pulse) < 120 beats per minute Estimated or known age 16-45 No suspicion of pregnancy Esophageal/rectal probe temperature > 35.5°C (Pre-hospital cooling only) Injured < 2 hours prior to arrival of pre-hospital providers  Following commands upon EMS arrival without deterioration to coma or follows command after an initial period of coma Mechanism of injury GSW or no indication of head injury Systolic blood pressure < 120 mm Hg Diastolic blood pressure < 60 mm Hg Heart rate (pulse) > 120 beats per minute Estimated or know age > 45 or < 16 Suspected pregnancy Forehead scan temp < 35.5°C (Pre-hospital cooling only) Injured >2 hours prior to arrival of pre-hospital providers Evidence of major chest trauma (unilaterally absent breath sounds with tracheal deviation or distended neck veins or requiring thoracentesis
Patient description: An 8-year-old boy fell from his bike striking his left temple on the pavement. There was no immediate loss of consciousness, and a brief examination at the scene noted his pupils were symmetrical, reactive to the light, and he was moving all four limbs. Half an hour after the fall the child became drowsy, pale, and vomited. He was transferred to the emergency department. Upon arrival the heart rate was 52/min, blood pressure of 155/98. The Glasgow Coma Scale (GCS) was 6/15, the pupils were asymmetrical and movement of the right upper and lower extremities was impaired. The neurosurgical team advised deferring the CT scan in favor of initiating immediate treatment.

Clinical trial eligibility criteria: eligible ages (years): 9.0-18.0,  Traumatic Brain Injury English speaker Minimum birth weight of 2500 grams (5.5 lbs) and 37 weeks' gestation Additional for Children with Traumatic Brain Injury Head injury resulting in a post-resuscitation Glasgow Coma Scale score of either 13 to 15 or 3 to 8 No evidence of hypoxic injury  History of epilepsy, mental retardation, or documented evidence of developmental dysfunction Previous hospitalization for head injury involving loss of consciousness or post-concussional symptoms History of autism, major psychiatric disorder, or pervasive developmental delay History of meningitis or encephalitis History of child abuse History of chronic or uncontrolled serious physical disorders (cancer, uncontrolled diabetes, cystic fibrosis, etc.) Note: siblings of participants with TBI or orthopedically-injured comparison children will not be enrolled to maintain the independence of the groups
Patient description: An 8-year-old boy fell from his bike striking his left temple on the pavement. There was no immediate loss of consciousness, and a brief examination at the scene noted his pupils were symmetrical, reactive to the light, and he was moving all four limbs. Half an hour after the fall the child became drowsy, pale, and vomited. He was transferred to the emergency department. Upon arrival the heart rate was 52/min, blood pressure of 155/98. The Glasgow Coma Scale (GCS) was 6/15, the pupils were asymmetrical and movement of the right upper and lower extremities was impaired. The neurosurgical team advised deferring the CT scan in favor of initiating immediate treatment.

Clinical trial eligibility criteria: eligible ages (years): 17.0-70.0,  Traumatic Brain Injury Traumatic Brain Injury with a Glascow Coma Score < 9 (ie: severe head injury) Traumatic Brain Injury with a Glascow Coma Score > 8 with an intracranial pressure monitor in situ and CTscan evidence of one or more of the following: Cerebral oedema (Marshall grades III & IV), midline shift >5 mm cerebral contusion >3cm, evacuated subdural haematoma Enrolled within the first 48 hours after trauma Aged 17 ears  Has had a cardiac arrest at or post the trauma scene Pupils are fixed bilaterally and dilated >4mm,GCS=3 Coagulopathy sufficient to contraindicate surgery No chance of survival after consideration of CT and clinical findings Patients with lower limb/pelvic trauma excluded from Innercool monitoring only
Patient description: An 8-year-old boy fell from his bike striking his left temple on the pavement. There was no immediate loss of consciousness, and a brief examination at the scene noted his pupils were symmetrical, reactive to the light, and he was moving all four limbs. Half an hour after the fall the child became drowsy, pale, and vomited. He was transferred to the emergency department. Upon arrival the heart rate was 52/min, blood pressure of 155/98. The Glasgow Coma Scale (GCS) was 6/15, the pupils were asymmetrical and movement of the right upper and lower extremities was impaired. The neurosurgical team advised deferring the CT scan in favor of initiating immediate treatment.

Clinical trial eligibility criteria: eligible ages (years): 18.0-70.0,  Traumatic Brain Injury severe closed head injury patients or GCS 3-9 patients who receive brain oxygen monitoring ventriculostomy/ICP monitor at least one reactive pupil no known life threatening disease prior to trauma age 18-70 years old consent for microdialysis/brain 02 monitoring legal family representative present that can give informed consent for perfluorocarbon administration  no motor response both pupils fixed and dilated no consent available allergy to egg proteins coagulopathy major liver injury major pulmonary injury
Patient description: An 8-year-old boy fell from his bike striking his left temple on the pavement. There was no immediate loss of consciousness, and a brief examination at the scene noted his pupils were symmetrical, reactive to the light, and he was moving all four limbs. Half an hour after the fall the child became drowsy, pale, and vomited. He was transferred to the emergency department. Upon arrival the heart rate was 52/min, blood pressure of 155/98. The Glasgow Coma Scale (GCS) was 6/15, the pupils were asymmetrical and movement of the right upper and lower extremities was impaired. The neurosurgical team advised deferring the CT scan in favor of initiating immediate treatment.

Clinical trial eligibility criteria: eligible ages (years): 16.0-45.0,  Traumatic Brain Injury Non-penetrating brain injury with post-resuscitation Glasgow Coma Score (GCS) < 8 (motor 1-5) Estimated or known age > 16 and < 45 years old Time of Injury within 2.5hrs of arrival at hospital  GCS = 7 or 8 with a normal head Cat Scan (CT) scan or showing only mild Subarachnoid hemorrhage (SAH)or skull fracture or GCS > 9 post randomization GCS = 3 AND bilaterally non-reactive pupils Abbreviated Injury Score (AIS) > 4 for any body area except head Positive abdominal ultrasound or CT scan Persistent hypotension (systolic blood pressure < 110mmHGg) Persistent hypoxia (O2 Saturation < 94%) Positive pregnancy test Injured greater than 2.5 hours from hospital arrival Pre-existing medical conditions, if known
Patient description: An 8-year-old boy fell from his bike striking his left temple on the pavement. There was no immediate loss of consciousness, and a brief examination at the scene noted his pupils were symmetrical, reactive to the light, and he was moving all four limbs. Half an hour after the fall the child became drowsy, pale, and vomited. He was transferred to the emergency department. Upon arrival the heart rate was 52/min, blood pressure of 155/98. The Glasgow Coma Scale (GCS) was 6/15, the pupils were asymmetrical and movement of the right upper and lower extremities was impaired. The neurosurgical team advised deferring the CT scan in favor of initiating immediate treatment.

Clinical trial eligibility criteria: eligible ages (years): 0.0-17.0,  Traumatic Brain Injury Patients with a GCS </= 8 Glasgow Motor Score < 6 Closed head injury Age 0 < 18 y  Unavailable to initiate cooling within 6 hours of injury Glasgow Coma Scale (GCS) score = 3 and abnormal brainstem function Normal initial CT scan (No blood, fracture, swelling, and/or shift) Penetrating brain injury No known mechanism of injury Unknown time of injury Uncorrectable coagulopathy (PT/PTT > 16/40 sec, INR > 1.7) Hypotensive episode (Systolic Blood Pressure <5th percentile for age>10 min) Documented Hypoxic episode (O2 saturation < 94% for > 30 min) Pregnancy
Patient description: An 8-year-old boy fell from his bike striking his left temple on the pavement. There was no immediate loss of consciousness, and a brief examination at the scene noted his pupils were symmetrical, reactive to the light, and he was moving all four limbs. Half an hour after the fall the child became drowsy, pale, and vomited. He was transferred to the emergency department. Upon arrival the heart rate was 52/min, blood pressure of 155/98. The Glasgow Coma Scale (GCS) was 6/15, the pupils were asymmetrical and movement of the right upper and lower extremities was impaired. The neurosurgical team advised deferring the CT scan in favor of initiating immediate treatment.

Clinical trial eligibility criteria: eligible ages (years): 1.0-16.0,  Traumatic Brain Injury have a severe traumatic brain injury as defined by either a GCS ≤ 8 and an abnormal CT scan (intracranial hemorrhage, cerebral edema or diffuse axonal injury) or a motor score ≤ 3 and normal CT scan are aged between 1 and 16 years are mechanically ventilated  are not randomized by 6 hours after injury have penetrating brain injuries have fixed dilated pupils and GCS = 3 have proven cervical spinal cord injury have more than mild neurodevelopmental disability prior to injury have an acute isolated epidural hematoma and are expected to recover rapidly after surgical removal have had a post-traumatic seizure with a normal CT scan have refractory shock, defined as systolic blood pressure more than 2 standard deviations (SD) below the mean for age despite 80ml/kg intravenous fluid resuscitation
Patient description: An 8-year-old boy fell from his bike striking his left temple on the pavement. There was no immediate loss of consciousness, and a brief examination at the scene noted his pupils were symmetrical, reactive to the light, and he was moving all four limbs. Half an hour after the fall the child became drowsy, pale, and vomited. He was transferred to the emergency department. Upon arrival the heart rate was 52/min, blood pressure of 155/98. The Glasgow Coma Scale (GCS) was 6/15, the pupils were asymmetrical and movement of the right upper and lower extremities was impaired. The neurosurgical team advised deferring the CT scan in favor of initiating immediate treatment.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Minor Head Injury Intracranial Bleeding Traumatic Brain Injury Minor head injury, dizziness, nausea, vomiting  no injury to the head
Patient description: An 8-year-old boy fell from his bike striking his left temple on the pavement. There was no immediate loss of consciousness, and a brief examination at the scene noted his pupils were symmetrical, reactive to the light, and he was moving all four limbs. Half an hour after the fall the child became drowsy, pale, and vomited. He was transferred to the emergency department. Upon arrival the heart rate was 52/min, blood pressure of 155/98. The Glasgow Coma Scale (GCS) was 6/15, the pupils were asymmetrical and movement of the right upper and lower extremities was impaired. The neurosurgical team advised deferring the CT scan in favor of initiating immediate treatment.

Clinical trial eligibility criteria: eligible ages (years): 2.0-16.0,  Fractures Healthy pediatric emergency patients with isolated extremity injury requiring reduction  Active respiratory illness Seizure disorder Craniofacial abnormalities Allergy to soy, ketamine, or propofol Hypertension Significant renal, cardiovascular or neurologic disease