Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 12.0-999.0,  Tinea Pedis Ability and willingness to sign a written informed consent and /or assent (age appropriate). 2. Male or Female subjects 12 years of age or older. 3. A clinical diagnosis of interdigital tinea pedis on one or both feet characterized by clinical evidence of a tinea infection. 4. A sum of at least five (5) for signs (erythema and scaling) by the investigator on the selected target foot, and a score of at least five (5) for each symptom: pruritus (itching) and burning: and a sum of at least twelve (12) for both symptoms (pruritus and burning) by the subject on the PATSS. 5. Mycological evidence of the presence of fungi confirmed by the detection of fungal hyphae on a microscopic KOH wet mount. 6. Females of child-bearing potential must have a negative urine pregnancy test and must agree to use an effective form of contraception during the study . 7. Must be in good general health as determined by medical history and free of any disease that in the investigator's opinion might interfere with the study evaluations. 8. Must be able to communicate, be able to understand the study procedures, and be willing to comply with the study requirements  The presence of confluent diffuse moccasin-type tinea pedis. 2. Negative KOH microscopy test to assess presence of hyphae. 3. Onychomycosis of the toenails, involving ≥ 20% of the area of either great toenail or involvement of more than five toenails in total. 4. Concurrent tinea infection or bacterial skin infection on the feet. 5. Female subjects who are pregnant and/or nursing or planning a pregnancy during the course of the trial. 6. Recent history of or currently known to abuse drugs or alcohol. 7. History of intolerance or hypersensitivity to Econazole Nitrate, Mometasone Furoate, or other imidazole agents. 8. Presence of any other infection of the foot or other disease process that might confound the treatment evaluation. 9. Having a life-threatening condition or immunocompromised (e.g., autoimmune deficiency syndrome, cancer, unstable angina, or myocardial infarction) within the last 6 months. 10. Unable to communicate or cooperate with the investigator due to language barriers, poor mental development, or impaired cerebral function. 11. Current participation in a clinical drug research study or recent participation in a clinical trial within 30 days of Baseline. 12. Using the following medications prior to Baseline: 1. Antipruritics, including antihistamines within 3 days (72 hours). 2. Topical corticosteroids, antibiotics or antifungal therapies within 4 weeks. 3. Systemic corticosteroids, antibiotics or antifungal therapies within 12 weeks. 4. Oral terbinafine or itraconazole within 12 weeks. 5. Immunosuppressive medication or radiation therapy within 12 weeks. 6. Any other topical medicated topical treatments to the treatment area(s) within 7 days. -