semaj83/ctmatch_classification huggingface dataset:
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 60.0-999.0,  Osteoporosis Proximal Femur Fracture Selection of cases: women with hip fracture woman aged 60 years and more clinical suspicion of osteoporosis based on the following: trivial trauma (fall from the standing position), history of vertebral fracture or visualization of a vertebral fracture by CT availability of radiographs of the proximal femur (anteroposterior view of the pelvis mandatory; anteroposterior and lateral views of the fractured hip optional) signature by the patient of the informed consent document  patient under 60 years current bisphosphonate, oestrogen, or SERM treatment started more than 3 months earlier; or past treatment with these medications stopped less than 6 months earlier hip arthroplasty on the other side fracture at the site of a bone lesion psychiatric disorder that might prevent the patient from giving informed consent or from remaining completely still for about 15 minutes during the investigations informed consent document not signed by the patient Selection of controls The controls will be women without hip fracture matched on age to the cases woman aged 60 years and more signature by the patient of the informed consent document
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 55.0-999.0,  Post Menopausal Osteoporosis Adult patients, >/= 55 years of age Postmenopausal osteoporosis Patients who are in the opinion of the physician eligible to participate in this study
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 40.0-60.0,  Hot Flushes Menopause, Premature Obesity Vitamin D Deficiency Women in late menopausal transition or early menopause Age 40-55 BMI >25 kg/m2 Suffer from menopausal symptoms Change in previously regular cycles consisting of at least ≥2 skipped cycles and an interval of amenorrhea (≥60 days) in the last year Negative pregnancy test Vitamin D insufficiency (<30 ng/ml) Weight stability (+/ ) for 3 months  No period for >12 months Hormone use (i.e. menopausal hormone therapy, oral contraceptive, other hormonal medications) in last 3 months History of hysterectomy more than 11 months ago Abnormal screening blood tests (i.e. elevated serum calcium level, elevated creatinine) History of medical conditions where Vitamin D supplementation is not indicated (i.e. chronic renal insufficiency, elevated calcium, sarcoidosis or other granulomatous disease, lymphoma, or tuberculosis History of osteoporosis or osteoporosis on baseline DXA (expect less than 4% of screened population)84 Vitamin D deficiency (<10 ng/ml) as we felt it was unethical to withhold supplementation for 12 months in severe deficiency (according to our KPNW survey, this will <2% of population) Consuming more than 400 IU of Vitamin D supplementation daily (we felt such doses taken outside of the study design could confound results) Current smoker (within the last year) Taking medications that affect body weight
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 45.0-54.0,  Osteoporosis Osteopenia perimenopausal women willingness to participate in the 6-month study, willingness to undergo testing of bone turnover markers before and after the drug therapies and willingness to provide a self-assessment on quality of life and sleep throughout the program Subjects must be willing to take their treatments right before bed and to not to consume alcohol with this medication  will women in whom osteopenia is a result of some other known process such as hyperparathyroidism, metastatic bone disease, multiple myeloma or chronic steroid use Those individuals on osteoporotic drugs, hypnotics, CYP1A2 inhibiting drugs, fluvoxamine or those with severe sleep apnea, severe COPD and those with moderate or severe hepatic impairment will also be excluded Individuals who are lactose intolerant will also be excluded because the placebo and melatonin capsules will contain lactose
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 50.0-90.0,  Osteoporosis the risk of osteoporosis the risk of falls
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Osteoporosis, Postmenopausal Who have been diagnosed with postmenopausal osteoporosis by physician Who have received any oral bisphosphonates (weekly or monthly) at least for 2 months to provide answer of OPSAT-QTM questionnaire Who provide informed consent for study participation  Do not understand the contents of the questionnaire
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 55.0-85.0,  Post-Menopausal Osteoporosis in the cross-sectional part of the study which involves assessment of vitamin K status Informed consent to screening stage : assessment of vitamin K status serum vitamin K concentration < 0.15 ug/ml into the randomised controlled trial ambulatory post-menopausal women aged between 55-85 years 2. Post-menopausal osteoporosis ( history of previous fragility fractures or BMD evidence of osteoporosis or osteopenia with at least one clinical risk factors such as low BMI, positive family history of osteoporosis) 3. Treatment with a bisphosphonate and calcium/vitamin D supplements for at least 12 months 4. Informed written consent 5. e GFR >30 ml/min 6. normocalcaemia  Age <55 years, or > 85 years Male gender severe renal impairment (CKD stage 4 and 5) poor mobility (inability to walk 100 yards unaided) malabsorption (extensive bowel surgery, short bowel) generalised carcinomatosis glucocorticoid therapy inflammatory disorders (e.g. active rheumatoid arthritis, inflammatory bowel disease requiring oral glucocorticoids) endocrine diseases (e.g. primary hyperparathyroidism, hyperthyroidism) chronic liver disease
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 40.0-80.0,  Chronic Obstructive Pulmonary Disease age 40-80 years old cases: spirometry (post-bronchodilator) based diagnosis of COPD (GOLD criteria) + smoking history of at least 10 pack-years and active smoking behavior till at least 10 years from the moment of enrollment smoking controls: no COPD (spirometry based) + smoking history of at least 10 pack-years and active smoking behavior till at least 10 years from the moment of enrollment non-smoking controls: no COPD (spirometry based) + < 1 pack year  Respiratory disorder other than COPD α1-antitrypsin deficiency Known history of significant inflammatory disease other than COPD COPD exacerbation within 4 weeks prior to study Lung surgery Recent diagnosis of cancer Therapy with oral corticosteroids in the last 6 weeks Significant cardiovascular comorbidity Significant orthopedic/musculoskeletal problems
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Type 2 Diabetes Mellitus Have been diagnosed with type 2 diabetes mellitus Have an HgbA1c value ≥ 7% and ≤17% Are on basal insulin, with or without oral agents Are not on basal bolus insulin therapy Have had no severe hypoglycemic episodes in the 6 months prior to enrollment in the study. Severe hypoglycemia will be defined as any hypoglycemia that is both neurologically impairing and absolutely requires assistance from a third party in the form of carbohydrates, glucagon shots, or attention from a paramedic or other healthcare professional Have no known allergy to medical tape or sensors Are capable of and willing to test their blood glucose (BG) on an average of 4 times per day Are willing to not use Acetaminophen while enrolled in the study Are willing not to undergo a MRI procedure while wearing the CGM sensor Are willing and capable of performing self insertions of the device sensor  Have been on pump therapy in the 6 months prior to enrollment in the study Are receiving basal bolus insulin therapy Are taking any medication that is not approved to be taken with insulin Are pregnant or have intentions of becoming pregnant during the duration of the study Have any skin condition that would inhibit the proper wearing of the CGM sensor including severe psoriasis, burns, eczema, scarring, excessive tattoos, etc Have a hematocrit ≤30% or ≥55% Are currently enrolled in another clinical study (subjects must have ended participation in other studies at least 30 days prior to enrolling in this study Are employed by any company that manufactures or is developing a CGM device Are deemed incapable of participating in the study by the Primary Investigator for any reason
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Osteoporosis inherited low-turnover osteoporosis lumbar spine or hip BMD T-score ≤ -2.5 a written informed consent  age less than 18 years generally accepted contraindications for the treatment
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 20.0-45.0,  Adult Idiopathic Generalized Osteoporosis Premenopausal women, aged 20-45, with regular menses and no historical or biochemical secondary cause of osteoporosis Documented adult fractures judged to be low-trauma Must be willing to use effective contraception throughout the period of study drug administration vary slightly based on age category Premenopausal women ages 20-35 years must have at least one major osteoporotic fracture (excluding fractures of fingers, toes and face) AND low Bone Mineral Density(BMD) Premenopausal women above the age of 35 years should have a history of fracture AND/OR low BMD  History of any condition that increases the risk of osteosarcoma Early follicular phase serum Disorders of mineral metabolism Suspicion of osteomalacia Vitamin D deficiency Pregnancy or lactation within past 12 months Prolonged amenorrhea (> 6 months) during reproductive years (except pregnancy or lactation) Prior eating disorder Malignancy, except cured basal or squamous cell skin carcinoma Endocrinopathy: new onset untreated hyperthyroidism, hypothyroidism, Cushing's syndrome, prolactinoma
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 65.0-999.0,  Fall Fractures Aged over 65 years with normal renal function Normal transaminase levels Normal calcium blood levels Not homebound (not immobilized) nor in socio-healthcare institutions  Need for medical treatment with calcium or vitamin D Hypersensitivity to or contraindication for calcium or vitamin D Medical treatment that includes calcium or vitamin D Physical disability that impedes their collaboration Taking thiazide diuretics Oral anticoagulants Hormone replacement therapy Digitalis drugs Anticonvulsants or barbiturates Having any of the following diseases
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 60.0-999.0,  Osteoporosis Postmenopausal women or men > 60 years DXA T-Score at lumbar spine, total hip or femur neck <-2,0 before the start of the bisphosphonate therapy or at baseline or at least one low trauma vertebral fracture grade 2-3 or multiple low trauma vertebral fractures independent of bone mineral densitiy Pretreatment with bisphosphonates for at least four years Risk for hip and vertebral fractures min. 30% according to DVO-guideline for osteoporosis 2009 Signed informed consent  Other pharmacological treatment of osteoporosis during the last 48 months Other bone diseases Malabsorption syndromes Renal insufficiency with a calculated creatinine clearance < 35 ml/min Diseases of the esophagus, delayed esophageal clearance UUnability to realise the intake instructions Hypocalcemia
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Cervical Disc Degeneration Cervical Stenosis virgin spines no emergency operation age above 18 sufficient knowledge of the German language indication for anterior cervical discectomy and fusion absence of concomitant spinal disease  prior cervical surgery indications other than ACDF concomitant neoplastic, metabolic, severe general or infectious disease
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 30.0-90.0,  Osteoporosis Females Postmenopausal women Outpatients screened for osteoporosis Women > 45 years Women < 45 years under menopause Women obtained their consent to be measured  Premenopausal females Women without any symptom of menopause Women not obtained their consent to be measured
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 65.0-999.0,  Fall and Fracture Prevention. > age 65 Patient of the Centre for Family Medicine Family Health Team (CFFM FHT) Have at least one of the following or more falls in the past 12 months age 75 + high risk of fracture based on the CAROC difficulty with walking or balance as determined by attending physician acute fall history of a fragility fracture after the age of 50  moderate to severe cognitive impairment moderate to severe neurologic impairment not able to communicate in English contraindications to exercise as determined by physician uncontrolled hypertension palliative care, current cancer, on dialysis participation in a similar exercise program including resistance training at least 3 times a week
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 40.0-80.0,  Smoking Cessation COPD Active smokers over 40 years and more than 10 pack-years  Previous diagnosis of respiratory disease (asthma, COPD, interstitial lung disease) that cause alteration of spirometric pattern Patients with limitations in performing spirometry Age greater than 80 years Institutionalized patients Patients with a life expectancy less than 1 year Spirometry in the past 2 years
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 40.0-999.0,  Type 2 Diabetes Mellitus Osteoporosis inclusion:40-99 years old with type 2 DM patient exclusion:organization people
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 40.0-90.0,  Osteoporosis Postmenopausal women Diagnosis of osteoporosis in the medical record At least one prescription drug to treat osteoporosis in the last 5 years Insured by "Clalit" Health Services Hebrew-speaking capability and readiness to answer a questionnaire  Premenopausal women No diagnosis of osteoporosis in the medical record No treatment for osteoporosis in the last 5 years Women who do not speak Hebrew or are unable to answer a questionnaire
Patient description: A 51-year-old woman is seen in clinic for advice on osteoporosis. She has a past medical history of significant hypertension and diet-controlled diabetes mellitus. She currently smokes 1 pack of cigarettes per day. She was documented by previous LH and FSH levels to be in menopause within the last year. She is concerned about breaking her hip as she gets older and is seeking advice on osteoporosis prevention.

Clinical trial eligibility criteria: eligible ages (years): 50.0-999.0,  Diabetes Mellitus Osteoporosis Osteopenia Type 1 or type 2 diabetes Age ≥ 50 years Unaltered treatment of diabetes during the previous six months (no changes in drugs, but an increase or decrease in dose is accepted) and HbA1c is stable with a level of ± 1 in the same period HbA1c level≥ 7 % through the previous six months BMI between 19 og 35 Specific for type 2 diabetes Either treatment with metformin, sulfonylureas, dipeptidyl peptidase IV (DPP IV) inhibitors or glucagon-like peptide 1 (GLP-1) analogs Treatment with insulin and insulin in the combination with metformin, sulfonylureas, DPP IV inhibitors or GLP-1 analogs  HbA1C > 10% Pregnancy Metal implanted at both ankles and wrists Patients treated with: Antiresorptive (incl. hormone replacement therapy) or bone anabolic treatment, glucocorticoids, lithium and anticonvulsives Patients with a bone disease other than osteoporosis Vertebral fracture visible by vertebral fracture assessment (VFA) Patients with renal disease defined by estimated glomerular filtration rate(eGFR) < 50 Other medical disease in unstable phase (fx. cancer, hyperthyroidism) Heart failure; New York Heart Association (NYHA) class IV Patients which the investigator does not believe is fit to participate in the study