semaj83/ctmatch_classification huggingface dataset:
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Achalasia Alacrima early age onset primary achalasia patient less than 35 years old  secondary achalasia patients
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 20.0-45.0,  Premenstrual Syndrome Person is over the age of 20 but not older than age 45 Person is willing to participate as evidenced by signing the written informed consent form Suffers from known dominant severe symptom of breast swelling and tenderness (level 7-10 according to standard scale of PMS symptoms severity) Other severe symptoms of Premenstrual syndrome (based on WHO and ACOG criteria). This may one or more of PMS symptoms with level 7-10 according to standard scale of PMS symptoms severity At work, school, home, or in daily routine, at least one of the PMS symptoms caused reduction of productivity or inefficiency At least one of the PMS symptoms caused avoidance of or less participation in hobbies or social activities At least one of the PMS symptoms interfere with relationships with others i. Timing of PMS symptom(s): during the 14 days prior to onset of menstrual flow (rather than spotting) and up to 5 days during the menstrual flow ii. Pattern and length of PMS symptomatic period: minimum of 2 days, up to 14 days iii. For PMS diagnosis two out of last three consecutive menstrual cycles were monitored by daily monitoring of symptoms  Pregnant or lactating woman Oral contraceptives during last three months, including hormonal IUD (trade name mirena) Serious health problems Unexplained menstrual disorders Treated by hormones (estrogen and progesterone) For healthy: Irregular or abnormal test results
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-40.0,  Contraception Healthy female subjects in need for contraception will be selected to participate in the trial Each subject must be >=18 to <=40 years of age at screening and in need for contraception Each subject must have given birth to at least one child (gestational age >=28 weeks) Each subject must have a uterus with a measured length between 6.0 and 9.0 cm (extremes included) from external os to fundus uteri  A subject must not be pregnant or suspected to be pregnant A subject must not have had an ectopic pregnancy in the past or must not have a history or presence of predisposing factors for this condition such as salpingitis, endometritis or pelvic peritonitis A subject must not have a history or presence of any malignancy A subject must not have a history or presence of premalignant disease of the uterus or cervix, including endometrial hyperplasia, or (other) sex-steroid sensitive premalignancies A subject must not have an active venous thromboembolic disorder (e.g. deep vein thrombosis, pulmonary embolism) A subject must not have a history or presence of severe hepatic disease with AST and/or ALT levels of >=3 times the upper normal limit A subject must not have congenital or acquired malformations or distortions of the uterus or cervix A subject must not have large or multiple uterine fibromyomata, or a smaller uterine fibromyoma which may interfere with the insertion of the MIUS/IUD according to the investigator A subject must not have vaginal bleeding of undiagnosed etiology A subject must not have dysmenorrhea interfering with daily activities or menorrhagia
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Hypertension age 18 years or older stage I or II hypertension defined as: a mean seated cuff diastolic blood pressure >=95 and <=115 mmHg ability to provide written informed consent  severe hypertension defined as: a mean seated cuff diastolic blood pressure >=116mmHg or a mean seated cuff systolic blood pressure >=200mmHg known or suspected secondary hypertension(ex. aortic coarctation, Primary hyperaldosteronism, renal artery stenosis, pheochromocytoma) has severe heart disease(Heart failure NYHA functional class 3, 4), unstable angina or myocardial infarction, arrhythmia within the past three months has cerebrovascular disease as cerebral infarction, cerebral hemorrhage within 6 months Type I Diabets Mellitus, Type II Diabetes Mellitus with poor glucose control as defined by fasting glucosylated hemoglobin(HbA1c) > 8% known severe or malignant retinopathy hepatic or renal dysfunction as defined by the following laboratory parameters: AST/ALT > UNL X 2, serum creatinine > UNL X 1.5 acute or chronic inflammatory status need to treatment need to additional antihypertensive drugs during the study need to concomitant medications known to affect blood pressure during the study
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 40.0-60.0,  Hot Flushes Menopause, Premature Obesity Vitamin D Deficiency Women in late menopausal transition or early menopause Age 40-55 BMI >25 kg/m2 Suffer from menopausal symptoms Change in previously regular cycles consisting of at least ≥2 skipped cycles and an interval of amenorrhea (≥60 days) in the last year Negative pregnancy test Vitamin D insufficiency (<30 ng/ml) Weight stability (+/ ) for 3 months  No period for >12 months Hormone use (i.e. menopausal hormone therapy, oral contraceptive, other hormonal medications) in last 3 months History of hysterectomy more than 11 months ago Abnormal screening blood tests (i.e. elevated serum calcium level, elevated creatinine) History of medical conditions where Vitamin D supplementation is not indicated (i.e. chronic renal insufficiency, elevated calcium, sarcoidosis or other granulomatous disease, lymphoma, or tuberculosis History of osteoporosis or osteoporosis on baseline DXA (expect less than 4% of screened population)84 Vitamin D deficiency (<10 ng/ml) as we felt it was unethical to withhold supplementation for 12 months in severe deficiency (according to our KPNW survey, this will <2% of population) Consuming more than 400 IU of Vitamin D supplementation daily (we felt such doses taken outside of the study design could confound results) Current smoker (within the last year) Taking medications that affect body weight
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Uterine Hemorrhage Signed and dated informed consent Healthy female subjects requesting contraception Age: 18 years inclusive Successful interval insertion of History of regular cyclic menstrual periods Normal or clinically insignificant cervical smear not requiring further follow up  Pregnancy or lactation Climacteric symptoms prior to the screening visit Known or suspected clinically significant ovarian cysts, endometrial polyps, fibroids, or other genital organ pathology, that, in the opinion of the investigator, may interfere with the assessment of the bleeding profile during the study Undiagnosed abnormal genital bleeding Current or history of thrombembolic disease, or established risk factors for venous thromboembolism Current migraine, focal migraine with asymmetrical visual loss or other symptoms indicating transient cerebral ischemia, or exceptionally severe headaches Hypersensitivity to any ingredient of the investigational medicinal products or the non-investigational medicinal product Daily or frequent use of a nonsteroidal anti-inflammatory drug (NSAIDs) for any condition Not willing to use nonsteroidal anti-inflammatory drug (NSAIDs) medication as pain medication during the double blind treatment period
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-40.0,  Healthy Middle-aged Subjects Age Range Was 18 to 31 Years Caucasian Whites Males and Females healthy middle-aged subjects  volunteers with systemic or ocular diseases
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Cyclic Mastodynia Premenstrual Syndrome Females aged 18 to 45 who have signed an Informed Consent Form (ICF) at screening visit S-2 (screening visit -2) at the latest Subject has a history of cyclic mastodynia and premenstrual syndrome Stable cycle duration of 25 to 35 days during the past 6 months before screening visit S-2 At screening visit S-2 subject is reporting at least one physical premenstrual syndrome symptom rated moderate or severe (lead symptom requiring treatment) and one psychic symptom for the late luteal phase of the preceding cycle, using the Calendar of Pre-menstrual Experiences (COPE) symptom list At screening visit S-2 subject is reporting symptoms of a total score of at least 15 in the late luteal phase of the preceding cycle, using the Calendar of Pre-menstrual Experiences (COPE) symptom list In both run-in cycles Visual analog scale greater or equal 50 mm at least on one of the days of the late luteal phase Cyclic course of the mastodynia, i.e. visual analog scale in the mid follicular phase (maximum value of 5 daily recordings) is less than 75 % of the visual analog scale in the late luteal phase (maximum value of 5 daily recordings) Premenstrual syndrome sum score resulting from Calendar of Pre-menstrual Experiences (COPE) must be 20 or more in the late luteal phase (average of daily recordings documented on days -5 to -1) At least one physical premenstrual syndrome symptom must have been rated moderate or severe on at least one day of the late luteal phase, and one psychic symptom is present  Pre Menstrual Dysphoric Disorder Intake of any of the following medications before treatment start (visit S-2 up to visit V0) and within 6 months prior to visit S-2 Any treatment for mastodynia or premenstrual complaints Sexual hormones, combinations and inhibitors Pituitary hormones and their inhibitors Hypothalamic hormones Neuroleptics, antidepressants Serotonin-re-uptake-inhibitors Prolactin-inhibitors or prolactin stimulating preparations
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-44.0,  Infertility infertile females with preserved gonadal function ages 18 years old included first oocyte donation cycle  BMI: > 28 recurrent miscarriages (3 or more) recurrent of implantation failure severe male factor important miomas > 44 years old Problems with the drugs used in the study
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 45.0-55.0,  Perimenopausal Depression Females who are currently physically well and between 45 and 55 years of age Current DSM-IV diagnosis of depression disorder Able to give informed consent Perimenopausal as determined by symptom profile on the Stages of Reproductive Aging Workshop and gonadal hormonal profile  Known abnormalities in the hypothalamic-pituitary gonadal axis, thyroid dysfunction, central nervous system tumours, active or past history of a venous thromboembolic event, breast pathology, undiagnosed vaginal bleeding or abnormal Pap smear results in the previous 2 years Patients with any significant unstable medical illness such as epilepsy and diabetes or known active cardiac, renal or liver disease; or the presence of illness causing immobilisation Patients receiving treatment for depression including antidepressant medications, electroconvulsive therapy (ECT) / Transcranial Magnetic Stimulation (TMS), formal psychotherapy or counselling, within the past 6 months Patients experiencing severe melancholia, neurovegetative symptoms or current suicidality necessitating acute hospitalisation or intensive psychiatric treatment Patients with psychotic symptoms or past history of severe mental illness including schizophrenia, and bipolar disorder Use of any form of estrogen, progestin or androgen as hormonal therapy, or antiandrogen including tibolone or use of phytoestrogen supplements as powder or tablet Pregnancy / Lactation Smoking cigarettes and other nicotine products illicit drug use and more than 3 standard drinks per day
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Uterine Fibroids Age>18 years Premenopausal Symptomatic fibroids Fibroids accessible for focused ultrasound treatment  Desires future fertility Current pregnancy Hematocrit <30% Emergency room visit in last 3 months for fibroid symptoms History of venous thromboembolism Fibroids that are: >10cm, non-enhancing with contrast Adenomyosis Contraindications to undergoing MRI Unexplained menstrual irregularity
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 20.0-40.0,  Endometriosis for patients with endometriosis Female patients with ovarian endometriosis, peritoneal and recto-vaginal Aged between 20 and 40 Signing of informed consent for collection and storage of biological samples  Contraindications for endometrial biopsy Failure to sign informed consent for collection and storage of biological samples
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 0.0-21.0,  Menorrhagia Menstruating females with menorrhagia or menometrorrhagia referred to hematology or gynecology clinics at Texas Childrens Hospital. Menorrhagia is defined as regular periods with heavy menstrual bleeding with a PBAC score greater than 100; menometrorrhagia is heavy vaginal bleeding occurring at irregular intervals PBAC Score greater than 100 for 2 consecutive cycles Pelvic ultrasound that excludes pelvic pathology that can cause menorrhagia within 12 months prior to study participation Normal external genitalia examination within 6 months prior to study participation Normal thyroid stimulating hormone (TSH) in the last 6 months prior to study participation Negative urine or serum pregnancy test within 4 weeks prior to study participation  Presence of intra uterine device Presence of a diagnosed bleeding disorder based on the standard work-up including complete blood count (CBC), prothrombin time, partial thromboplastin time, fibrinogen, von Willebrand panel and platelet function analysis (PFA-100) or platelet aggregation Intake of medications with increased risk of bleeding Taking herbal products Sexually active status Body weight less than 40 kg
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-35.0,  Copper Intrauterine Device Induced Bleeding Regularly menstruating women before CIUD insertion Age between 18 and 35 years Hormonal treatment has not been taken at least two months before the study Non steroidal anti-inflammatory drugs has not been taken 24 hours before the examination  Pregnancy The presence of pelvic pathology as ovarian cysts, pelvic endometriosis, endometrial polyps or fibrosis Present or past history of pelvic inflammatory disease Patients on hormonal treatment in the last two months before the study Patients on non steroidal anti-inflammatory drugs last 24 hours before the examination
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-55.0,  Uterine Fibroids Women, age between 18 and 55 years Weight < 140 kg Pre or peri-menopausal Uterine size < 24 weeks Cervical cell assessment by Pap smear/Thin-prep Cytologic Test (TCT): Normal, Low Grade Squamous Intraepithelial Lesion (SIL), Low risk Human Papillomavirus (HPV) or Atypical Squamous Cells of Uncertain Significance (ASCUS) subtypes of cervical tissue Fibroids selected for treatment meeting the following Total planned ablation volume of all fibroids should not exceed 250 ml, and No more than 5 fibroids should be planned for ablation, and Dominant fibroid (diameter) is greater than or equal to 3 cm, and  Other pelvic disease (Other mass, endometriosis, ovarian tumor, acute pelvic disease, significant adenomyosis) Desire for future pregnancy Significant systemic disease, even if controlled Positive pregnancy test Hematocrit < 25% Extensive scarring along anterior lower abdominal wall (> 50% of area) Surgical clips in the direct path of the HIFU beam MRI contraindicated MRI contrast agent contraindicated Fibroids not quantifiable on MRI (e.g. multi-fibroid cases where volume measurements are not feasible)
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 20.0-45.0,  Adenomyosis Women have dysmenorrhoea and/or chronic pelvic pain secondary to adenomyosis Planning for birth spacing for at least 2 years Patient aged between 20-45 years old Ultrasonographic and Doppler examination suggestive of adenomyosis Living in a nearby area to make follow-up reasonably possible  Pregnancy Evidence of defective coagulation History or evidence of malignancy Hyperplasia in the endometrial biopsy Incidental adnexal abnormality on ultrasound Contraindications to COCs Absolute contraindication of LNG-IUS insertion Previous endometrial ablation or resection Uninvestigated postcoital bleeding Untreated abnormal cervical cytology
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 21.0-999.0,  Uterine Fibroids Premenopausal (at least 1 menstrual period in last 3 months) Age >21years Fibroids are associated with heavy bleeding, pelvic pressure or discomfort, urinary or bowel symptoms, or dyspareunia Desires surgical management of fibroids Uterus ≤16 weeks in size All fibroids ≤ 10cm in maximum diameter by ultrasound or MRI assessment within the last year Total number of fibroids ≤6 by ultrasound or MRI assessment within the last year. (For this study "Fibroids" will be leiomyomas > 2cm) Had a Pap smear within the last 3 years with appropriate follow-up and treatment for cellular abnormalities Endometrial biopsy indicates no hyperplasia or cancer (biopsy only required if age >45 years and has anovulatory heavy bleeding) Able to tolerate laparoscopic surgery  Planned treatment for infertility Pedunculated fibroid with thin stalk (total stalk length is <25% maximum diameter of fibroid) Intracavitary (FIGO Type 0) fibroid Symptomatic fibroids are only FIGO Type 1 (submucosal with ≥ 50% intracavitary) Planned concomitant surgical procedure in addition to treatment of uterine fibroids Use of Essure or any other metallic, implantable device within pelvis Pregnancy Pelvic infection with the last 3 months History of pelvic malignancy and/or pelvic radiation Known or high suspicion for dense pelvic adhesions
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Low Back Pain Symptom of low back pain during last 4 weeks Low back pain history for more than 3 months  Have lower limbs radiating pain beyond knee joints Spinal tumorous or infectious disease, fracture, ankylosing spondylitis, cauda equina syndrome or other severe spinal diseases Spinal surgical history Severe heart, lung, liver, kidney disease or high blood pressure With cardiac pacemaker Coagulopathy or thrombosis Have ESW therapy or pharmaceutical treatment for low back pain during last 1 months Mental illnesses or none cooperation Pregnancy
Patient description: A 38 year old woman complains of severe premenstrual and menstrual pelvic pain, heavy, irregular periods and occasional spotting between periods. Past medical history remarkable for two years of infertility treatment and an ectopic pregnancy at age 26.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Uterine Leiomyomas Fibroids Uterine Fibroids Myomas Able and willing to give consent Age 18 or older Presence of known uterine leiomyoma  Suspected malignancy