Patient description: 19 yo Hispanic female G1P1 at 32+ 6 weeks of gestational age presented to the OB clinic for routine follow up complaining of mild headache and leg swelling. Primary evaluation revealed BP of 146/99 and urine dipstick with 3+ proteins. Her BP and U/A were normal in previous visit. Repeat BP a few hours later is 150/100 mmHg. Laboratory studies showed a normal hematocrit, platelet count, and liver transaminase levels. She is complaining of fatigue but no fever or chills. She is also suffering of headaches with no vision changes. No shortness of breath, cough, chest pain, orthopnea and palpitations or skin rash were observed. Her physical exam was negative for abdominal pain, change in bowel habits, nausea, vomiting, dysuria, frequency, hematuria or frothy urine. Leg swelling was observed with no arthralgia or back pain. She has no specific past medical issues and only uses prenatal vitamins. Her family history is positive for DM type 2 and HTN. She is a social alcohol consumer with the negative history of smoking or drug use. She is only have one partner in past 2 years and didn't have any contraceptive methods since 2 years ago. Her BMI was 24 at the first

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Parkinson Disease Male or female subjects aged between 18 and 45 years, inclusive Subjects of body mass index (BMI) between 19 and 30 kg/m2, inclusive Subjects who were healthy as determined by pre-study medical history, physical examination, vital signs, complete neurological examination and 12-lead ECG Subjects who had negative tests for HBsAg, anti-HCVAb and HIV-1 and HIV-2 Ab at screening Subjects who had clinical laboratory test results clinically acceptable at screening and admission Subjects who had a negative screen for alcohol and drugs of abuse at screening and admission Subjects who were non-smokers or who smoked ≤ 10 cigarettes or equivalent per day Subjects who were able and willing to gave written informed consent (If female) She was not of childbearing potential by reason of surgery or, if of childbearing potential, she used one of the following methods of contraception: double barrier, intrauterine device or abstinence (If female) She had a negative urine pregnancy test at screening and admission  Subjects who had a clinically relevant history or presence of respiratory, gastrointestinal, renal, hepatic, haematological, lymphatic, neurological, cardiovascular, psychiatric, musculoskeletal, genitourinary, immunological, dermatological, endocrine, connective tissue diseases or disorders Subjects who had a clinically relevant surgical history Subjects who had a clinically relevant family history Subjects who had a history of relevant atopy Subjects who had a history of relevant drug hypersensitivity Subjects who had a history of alcoholism or drug abuse Subjects who consumed more than 14 units of alcohol a week Subjects who had a significant infection or known inflammatory process on screening or admission Subjects who had acute gastrointestinal symptoms (e.g., nausea, vomiting, diarrhoea, heartburn) at the time of screening or admission Subjects who had used medicines within 2 weeks of admission that may affect the safety or other study assessments, in the investigator's opinion