Patient description: The patient is a 15 year old girl with the history of recurrent bilateral headache. The attacks come 2 times or more per week and each episode lasts around a day or a half. The pain is pulsating in quality and severe in intensity, causing trouble in her routine physical activity. The attacks are associated with nausea and photophobia. She recently noticed that that there are more attacks around her menstrual period. She is diagnosed with the migraine headache and is under treatment. She is a high-school student and living with her both parents. She is a book worm and spend her free time in a public library near her home. She is also interested in writing stories and has several short stories in English. She rarely does exercise. Her BMI is 21 with the BP of 100/60. There is nothing remarkable in her physical exam.

Clinical trial eligibility criteria: eligible ages (years): 18.0-75.0,  Migraine Headaches A history of episodic migraine who experience an average of 2 to 8 migraine attacks per month for at least the past 12 months, with no more than 14 headache days per month, and with 48 hours of headache free time between migraine headaches 2. Patients who have migraine with or without aura. If migraine with aura, the aura cannot last longer than 60 minutes. 3. Patients who are willing and able to: 1. Evaluate and record pain, migraine symptoms, and study medication effectiveness information in real-time using a diary for the duration of the study; 2. Record each instance of the use of study medication and rescue medication in a patient diary in real-time for the duration of the study; 3. Comply with all other study procedures and scheduling requirements  Minors, even if they are in the specified study age range 2. Medication overuse: 1. Opioids ≥ 10 days during the 90 days prior to screening 2. Combination medications (e.g., Fiorinal®) ≥ 10 days during the 90 days prior to screening (only applies if combination medication contains an opioid and/or barbiturate) 3. Nonsteroidal Anti-inflammatory Drugs or other simple medications ˃ 14 days a month during the 90 days prior to screening 4. Triptans or ergots ≥ 10 days a month during the 90 days prior to screening 3. Treated with onabotulinumtoxinA (Botox®) or other botulinum toxin treatment within 4 months prior to screening for migraine prophylaxis (patients who were treated with same for cosmetic purposes may be allowed on a case-by-case basis after approval from the Medical Monitor) 4. A history of or current neurological or psychiatric impairment, or cognitive dysfunction that, in the opinion of the Investigator, would compromise data collection 5. Use of antipsychotics at least 15 days prior to randomization 6. Patients who received treatment with an investigational drug or device within 30 days prior to randomization, or within 3 months if associated with central nervous system 7. Patients who participated in a central nervous system clinical trial within 3 months prior to randomization 8. Patients who test positive for human immunodeficiency virus (HIV), hepatitis B surface antigen (HBsAg), or hepatitis C virus (HCV) antibody serology testing 9. Patients who are employees or immediate relatives of the employees of the Sponsor, any of its affiliates or partners, or of the clinical study research site