semaj83/ctmatch_classification huggingface dataset:
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-55.0,  Major Depressive Disorder Diagnosed with recurrent major depressive disorder  Patients with treatment resistance for depression History of alcohol abuse/dependence, substance abuse/dependence within 6 months Has clinically significant unstable medical condition Has significant risk of suicide
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Melanoma Survivors Psychological Factors For the focus group recruitment (Specific Aim 1) Patients with melanoma (invasive primary cutaneous melanoma, stages 1-III), who have been treated at MSKCC from 1996-2005 For the survey group recruitment (Specific Aim 2): patients with melanoma (invasive primary cutaneous melanoma, stages 1-III), who have been treated at MSKCC from 2001-2011• Ability to sign informed consent which indicates the psychosocial, behavioral, epidemiological nature of this study • Age ≥ or = to 18 years and fluent in the English language  Patients with intraepithelial (in situ) melanoma Patients with stage IV melanoma Patients with nodal or visceral melanoma without a documented primary lesion Patients with prior malignancies For the focus group recruitment (Specific Aim 1): (patients treated at MSKCC from 1996-2005) who have a diagnosis >10 years ago from treatment. For the survey group recruitment (Specific Aim 2): patients treated at MSKCC from 2001-2011)who have a diagnosis >10 years ago from treatment Patients with a recent diagnosis of melanoma, <12 months Patients who are one year or more post diagnosis and are still receiving treatment for their melanoma
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Major Depressive Disorder Male or female outpatients Aged 18-65 who meet the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition, Text Revision (DSM-IV-TR) diagnostic for Major Depressive Disorder (MDD) Have a Montgomery-Asberg Depression Rating Scale (MADRS) total score of at least 22 at visits 1 and 2 Have a Clinical Global Impressions of Severity Scale (CGI-S) score of at least 4 at visits 1 and 2 Have a degree of understanding such that the patient can provide informed consent, complete protocol required assessments and communicate intelligibly with the investigator and study coordinator  Patients judged clinically to be at serious suicidal risk in the opinion of the investigator Patients who have any prior history of bipolar disorder, psychosis, or schizophrenia Patients who have any current (within the past six months) DSM-IV-TR primary Axis I disorder other than MDD Patients with uncontrolled narrow-angle glaucoma Patients who have a serious medical illness that is in the opinion of the investigator not stabilized or is likely to require intervention, hospitalization, or use of an excluded medication during the course of the study
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-70.0,  Major Depression Current MDD or MDD within the past year or current dysthymia PHQ-9 > 10 have been prescribed an antidepressant medication (by their PCP) at least 8 weeks before pre-treatment timepoint are able to speak, read, and understand English sufficiently well to complete study procedures are between the ages of 18 and 70  presence of significant suicidal ideation or risk history of bipolar disorder, schizophrenia, psychotic symptoms, or severe alcohol or drug problems within the past year history of antisocial personality disorder or borderline personality disorder currently in psychotherapy or have received counseling more frequently than once per month in the past year
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Depression Patients meeting for a diagnosis of major depression, single or recurrent episode as described by the DSM-IV manual (appendix 1) A HAM-D 17 total score of at least 16 at baseline (DSM-IV manual, appendix 2) Patients above 18 years of age who meet the requirements  Patients taking MAOI's within 2 weeks prior to the survey Patients known to be suffering from bipolar disorder or schizophrenia Patients who are treatment-resistant, i.e., in the past 3 years have failed (a) three previous adequate trials of greater than or equal to 2 classes of antidepressant medication, or (b) electroconvulsive therapy Drug or alcohol dependence or abuse in the past 6 months per DSM IV criteria
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-40.0,  Depression Pregnant woman between 18 and 40 years of age Have depression as their only mental health disorder Have been receiving fluoxetine or citalopram for the treatment of depression for at least one month on the day of study entry for patients in the fluoxetine and citalopram arms, or no pharmacological treatment for patients in the control arm ≤ 26 weeks pregnant by estimated date of confinement Ability to give informed consent Singleton pregnancy Pregnant women no history of depression  Having any comorbid mental disorder other than generalized anxiety disorder as a secondary disorder History of or current epilepsy, endocrine, cardiac, pulmonary, renal or hepatic dysfunction that could negatively influence pregnancy and/or neonatal outcome Abusing alcohol or drugs Use of any self prescribed herbal treatments for depression
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Antidepressant Induced Sexual Dysfunction Subject is female, age 18 to 80 years Subject has been taking an SSRI, venlafaxine, or tri/heterocyclic antidepressant for the treatment of depression for at least 8 weeks; and is currently on a stable dose of the antidepressant for at least 4 weeks Subject is currently euthymic (HAM-D < 10) and is without significant anxiety symptoms (HAM-A < 10) Subject must have had no sexual dysfunction prior to taking antidepressant and there must be a clear temporal relationship between the sexual dysfunction and the antidepressant treatment Subject must have been consistently experiencing at least one of the following for at least 4 weeks, with distress or disability Inability to have an orgasm, according to patient opinion Clinically significant orgasm delay with masturbation or intercourse Inability to attain or maintain until completion of sexual activity an adequate lubrication swelling response of sexual excitement Decreased libido according to patient opinion Subject must be having or had been having some form of regular sexual activity (masturbation, oral sex, intercourse) at least twice monthly prior to the antidepressant treatment and are willing to continue efforts at sexual activity at least once weekly for the duration of the study  Primary or prior diagnosis of a sexual disorder (other than the side effect of the bipolar medication or symptom of the bipolar disorder) Sexual dysfunction secondary to general underlying medical condition Penile, vaginal, clitoral or other sexual organ anatomical deformities Any uncontrolled psychiatric disorder Alcohol or substance abuse or dependence within the past six months Recent major relationship changes, disruption, or turmoil ongoing or anticipated which are unrelated to her sexual dysfunction Hamilton Depression and/or Anxiety Scale score (either) > 10 Blood pressure outside the range of 90/50 100 Known hyperprolactinemia
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Depressive Disorder, Major Male or female = 18 years of age and < 60 years routine laboratory results within normal ranges Body Mass Index within the range 18.5-35.0 kg/m2 inclusive Subject must have had at least one previous major depressive episode with a diagnosis of MDD in his/her history, and had a successful pharmacological treatment of that episode, and is currently experiencing a recurrence of MDD presently un-medicated Subjects must met the diagnosis of an episode of Major Depressive Disorder in the past 12 weeks but not greater than 24 months  The subject has any history of liver disease The subject has significant cardiac, pulmonary, metabolic, renal, hepatic or gastrointestinal conditions that, in the opinion of the investigator and/or GSK medical monitor, places the subject at an unacceptable risk as a participant in this trial The subject has a history of autoimmune diseases The subject has any active infectious diseases, including active tuberculosis or a history of active tuberculosis The subject has a history of malignancy, except for surgically cured basal cell carcinoma or females with cured cervical carcinoma (> 2 yrs prior) The subject has a history of HIV or other immunosuppressive disease The subject has uncontrolled diabetes The subject is pregnant or nursing Subject has no contact with an adult on a daily basis (i.e., subjects who are not living with at least one other adult or subjects who do not have an adult who contacts them on a daily basis) Subject has initiated psychotherapy within three months prior to the Screening visit, or plans to initiate psychotherapy during the trial
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-82.0,  Cancer of the Esophagus years of age or older Histologically or cytologically documented squamous cell carcinoma or Siewert's classification adenocarcinoma of the esophagus or proximal stomach T1-4, N0-2, M0-1, for which bimodality treatment with chemotherapy and radiation therapy is indicated Measurable Disease ECOG Performance Status 0-1 Laboratory values must be as follows Absolute neutrophil count > or = 2,000/mm3 Platelets > or = 100,000/mm3 Hemoglobin > 9.0 Total bilirubin <1.5 x institutional upper normal limit Serum creatinine <1.5 x institutional upper normal limit  Tumors extending above the level of the thoracic inlet or beyond 5 cm below the gastroesophageal junction Patients with radiographic or bronchoscopic evidence of esophageal perforation Patients with known evidence of brain metastases, lymphangitic lung metastases, or carcinomatous meningitis Dementia or significantly altered mental status Major surgery within 4 weeks of the start of study treatment Prior chemotherapy, radiation therapy, hormonal or biologic therapy within the past 6 months Subjects requiring chronic use of immunosuppressive agents (e.g., methotrexate, cyclosporine, corticosteroids) Currently requiring medications that may interact with the metabolism or disposition of capecitabine/5-FU: dipyridamole, folinic acid, allopurinol, trimethoprim, misonidazole, metoclopramide, flucytosine or cimetidine Hypersensitivity to platinum containing compounds or capecitabine or any of the excipients of this product. Prior unanticipated severe reaction to fluoropyrimidine/platinum therapy, or known sensitivity to 5-fluorouracil/platinum containing compounds Serious, uncontrolled, concurrent infection(s)
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-64.0,  Bipolar Disorder Depression Normal or corrected-to-normal vision (tested by vision charts) Diagnosis of bipolar I disorder by the Mini International Neuropsychiatric Interview (MINI) HAM-D score of 17 or higher  Meets for DSM-IV bipolar I disorder subtype rapid cycling Meets for DSM-IV mixed episode Pregnant Serious medical illness Neurologic disorder and/or head trauma Current or past history of selected DSM-IV Axis I disorders other than bipolar disorder, including organic mental disorder, schizophrenia, delusional disorder, and psychotic disorders not otherwise specified Substance abuse or dependence within the 12 months prior to study entry and/or history of substance abuse for more than 12 months IQ of less than 80 on the Wechsler Adult Reading Test Previous treatment with CBT for depression Contraindications to MRI (e.g., metallic implants, claustrophobia)
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-50.0,  Depression, Postpartum Primary DSM-IV diagnosis of major depressive disorder by clinical interview Score of greater than 12 on HAM-D Delivery of an infant within the 12 months prior to study entry Able to speak and read English sufficiently to complete the study procedures Willing to use effective birth control methods throughout the study  Woman whose infant has died prior to study entry Current or past diagnosis of bipolar disorder, schizophrenia or other psychotic disorder Diagnosis of alcohol or drug abuse or dependence (except nicotine) or anorexia in the past year Psychotic symptoms Acute suicidal or homicidal risks Women who have been on an antidepressant for more than 14 days prior to consent, (if less than 14 days and willing to taper off, will be eligible to continue once tapered off) Women on daily anxiolytic medication (i.e. benzodiazepine, buspirone) or daily psychoactive herbal preparation (St. John's Wort or Fish Oil) (if willing to discontinue these substances may be eligible once they have been tapered off) Medications taken PRN over the listed dose and frequency (women will still be eligible if they take: Lunesta/Eszopiclone 3 mg or less, up to 3 nights a week, Ambien/Zolpidem 5mg or less, Ambien CR 6.25 mg or less, up to 3 nights a week, Lorazepam or equivalent benzodiazepine dose: 0.5 mg up to 3 nights a week, Sonata/Zaleplon: 5 mg or less, up to 3 nights a week, Rozerem/Ramelteon: 8 mg or less, up to 3 nights a week) If they take antidepressants PRN for insomnia (eg: Desyrel/Trazodone, Elavil/Amitriptyline, Remeron/Mirtazapine Ongoing concurrent psychotherapeutic treatment or psychotherapeutic treatment within the last month
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 20.0-65.0,  Depressive Disorder, Major Patients who fulfil ICD-10´s for major depression, found within the ambulant psychiatric sector and who has a HAM-D ≥ 18  If the patient has pacemaker or other magnetic devices Pregnancy Has had an operation in the brain bipolar disorder