Patient description: 19 yo Hispanic female G1P1 at 32+ 6 weeks of gestational age presented to the OB clinic for routine follow up complaining of mild headache and leg swelling. Primary evaluation revealed BP of 146/99 and urine dipstick with 3+ proteins. Her BP and U/A were normal in previous visit. Repeat BP a few hours later is 150/100 mmHg. Laboratory studies showed a normal hematocrit, platelet count, and liver transaminase levels. She is complaining of fatigue but no fever or chills. She is also suffering of headaches with no vision changes. No shortness of breath, cough, chest pain, orthopnea and palpitations or skin rash were observed. Her physical exam was negative for abdominal pain, change in bowel habits, nausea, vomiting, dysuria, frequency, hematuria or frothy urine. Leg swelling was observed with no arthralgia or back pain. She has no specific past medical issues and only uses prenatal vitamins. Her family history is positive for DM type 2 and HTN. She is a social alcohol consumer with the negative history of smoking or drug use. She is only have one partner in past 2 years and didn't have any contraceptive methods since 2 years ago. Her BMI was 24 at the first

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Healthy Volunteers Men and non-pregnant/lactating women between the ages of 18 and 45. 2. Self reported African American or Caucasian racial-ethnic background. 3. Body Mass Index (BMI) of ≥ 18 and ≤ 30. 4. Participants who are able to give written informed consent and willing to comply with all study-related procedures  Known clinically manifest atherosclerotic cardiovascular disease, including coronary disease, cerebrovascular disease, or peripheral vascular disease. 2. History of diabetes mellitus. 3. Fasting glucose > 126 mg/dL. 4. History of a non-skin malignancy within the previous 5 years. 5. Renal insufficiency as defined by creatinine > 1.5 mg/dl at Screening Visit. 6. History of liver disease or abnormal liver function tests (LFTs) (AST, ALT, Alk. Phos., GGT > 1.5x upper limit of normal (ULN); bilirubin > 2x ULN) at Screening Visit. 7. Men who are unwilling to limit alcohol consumption to <14 alcoholic drinks per week or < 4 alcoholic drinks per occasion (AMA / NIAAA for "at risk" usage levels) while participating in the study. 8. Women who are unwilling to limit alcohol consumption to < 7 alcoholic drinks per week or < 3 alcoholic drinks per occasion (AMA / NIAAA for "at risk" usage levels) while participating in the study. 9. Total white blood cell count less than or equal to 3.0 THO/uL. 10. Hemoglobin below 11.0 g/dL. 11. Any major active rheumatologic, pulmonary, or dermatologic disease or inflammatory condition or minor active infection. 12. History of HIV positive. 13. First degree family history of premature cardiovascular disease event (father or brother if diagnosed at before 55 years of age; mother or sister if diagnosed before 65 years of age). 14. Patients who have undergone any organ transplant. 15. Individuals who currently use tobacco products or have done so in the previous 30 days. 16. Treatment with aspirin, non-steroidal anti-inflammatory drugs (NSAIDs), COX-2 inhibitors, steroids or any immunomodulatory therapy 2 weeks prior to the Screening Visit. 17. Treatment with statins, fibrates or niacin 4 weeks prior to the Screening Visit. 18. Current daily use of Vitamin C > 1000 mg, Beta carotene > 1000 IU, vitamin A > 5000 IU, vitamin E > 400 IU, and selenium > 200 mcg. 19. Positive urine pregnancy at the Screening Visit. 20. Participation in another clinical trial within the previous 6 weeks prior to the Screening Visit. 21. Poorly controlled blood pressure (BP > 160/110) or on any anti-hypertensive medications. 22. A diagnosis of metabolic syndrome using updated 2004 NCEP criteria. 23. A history of severe lactose intolerance (e.g., intolerance of any milk intake). 24. Any medical condition or abnormal laboratory value that is judged clinically significant by an investigator