semaj83/ctmatch_classification huggingface dataset:
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 1.0-17.0,  Cardiovascular Diseases Coronary Aneurysm Heart Diseases Mucocutaneous Lymph Node Syndrome Boys and girls who met the CDC for Kawasaki Syndrome. Subjects were excluded if they presented themselves to the participating centers after the tenth day of illness
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 4.0-12.0,  Obsessive-Compulsive Disorder OCD Participants (N = 72) Aged 4-12 years and living within a four-hour commute from NIH Currently meet DSM-IV for OCD Recent onset of symptoms (less than 6 months.) Healthy Controls (N = 60-72) Age and sex matched to ODC participants Must be free of current or past psychopathology  OCD Participants Diagnosis of schizophrenia, schizoaffective, bipolar, delusional, or psychotic disorder; autistic spectrum disorder or pervasive developmental disorder; neurologic disorder other than tics; or rheumatic fever Significant or unstable medical illness Full scale IQ less than 80 Healthy Controls Full scale IQ less than 80 Significant or unstable medical illness
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 12.0-999.0,  Pharyngitis Tonsillitis Give informed consent, assent and patient authorization Age 12 and over A clinical diagnosis of acute pharyngitis or tonsillitis A positive rapid Strep test Can swallow the oral study dosage forms Females must have a negative urine pregnancy test and be using acceptable birth control if sexually active  Chronic or recurrent odynophagia Need for hospitalization or IV antimicrobial therapy Pharyngitis known or suspected due to a pathogen resistant to beta-lactam antimicrobials Known carrier of S. pyogenes Allergies to penicillin or other beta-lactam antibiotics Any serious illness or concomitant condition that the investigator judges will preclude to the study Seizure disorder Pregnant or nursing Expectation of additional systemic antibacterials would be required for another condition Current drug or alcohol abuse
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 0.5-12.0,  Pharyngitis Give informed consent, assent, and documentation of patient authorization for disclosure of study results Since all patients are below the legal age of consent, assent from the patient must be obtained (as applicable following state regulations) and written informed consent obtained from the parent or legal guardian Age > = 6 months -12 years A clinical diagnosis of acute tonsillitis and/or pharyngitis defined as having the clinical signs and symptoms compatible with tonsillitis and/or pharyngitis, including sore throat or difficulty feeding or swallowing or irritability that suggests the presence of a sore throat with at least one of the following Tonsillar or pharyngeal exudate Tender cervical lymph nodes Fever or history of fever treated with antipyretics Odynophagia Uvular edema Pharyngeal Erythema of moderate or greater intensity  Chronic or recurrent (two weeks duration two times per year) odynophagia or enlarged tonsils secondary to viral or proven bacterial etiology The need for hospitalization or I.V. antimicrobial therapy Pharyngitis known or suspected to be due to a pathogen resistant to beta-lactam antimicrobials Patients who are known carriers of S. pyogenes Previous allergy, serious adverse reaction to, or intolerance to, penicillin or any other member of the beta-lactam class of antimicrobials Any serious illness or concomitant condition that the investigator judges would preclude the study evaluations or make it unlikely that the course of study therapy and follow-up could be completed. This would also Any rapidly progressive underlying disease with a shortened life expectancy The inability to swallow the study dosage form Unable to understand the requirements of the study Neutropenia (<1000 PMNs/mm3) or other known immunocompromised state
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 3.0-15.0,  Streptococcus Group A All children 3 to 15-years old with pharyngitis who are seen at a participating site will be invited to participate  Subjects whose parents are unable or unwilling to provide informed consent will be excluded from the study Children who are 13 years or older and unable or unwilling to provide informed consent will be excluded form the study
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 12.0-999.0,  Sore Throat Pharyngitis Tonsillitis Informed consent/assent Age 12 and older A clinical diagnosis of acute tonsillitis and/or pharyngitis defined as having the clinical signs and symptoms compatible with tonsillitis and/or pharyngitis, including sore throat and pharyngeal erythema with at least one of the following Odynophagia Tonsillar or pharyngeal exudates Tender cervical lymph nodes Fever or history of fever treated with antipyretics Chills Uvular edema Elevated white blood cell count  Chronic or recurrent odynophagia or enlarged tonsils of obscure etiology More than one episode of acute tonsillitis and/or pharyngitis in the 6 months prior to baseline visit Pharyngitis known or suspected to be due to a pathogen resistant to β-lactam antimicrobials Subjects who are known carriers of S. pyogenes Previous allergies, serious adverse reaction to, or intolerance to penicillin or any other member of the β-lactam class of antimicrobials, including cephalosporins Any serious illness or concomitant condition that the Investigator judges would preclude the study evaluations or make it unlikely that the course of study therapy and follow-up could be completed. This would also Any rapidly progressive underlying disease with a shortened life expectancy The inability to swallow the study dosage form Unable to understand the requirements of the study Neutropenia (<1000 PMNs/mm3) or other immunocompromised state
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Streptococcal Infections Patients diagnosed with GAS infection/isolation in the past 3 years (2003-2005)
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 0.5-13.0,  Tonsillitis Pharyngitis Age 6 months to less than 13 years of age (<13) Clinical diagnosis of acute tonsillitis/pharyngitis caused by Streptococcus pyogenes based on A positive result from a rapid detection throat swab test for Group A streptococcal antigen and submission of a throat swab specimen for bacterial culture, identification, and antibiotic-susceptibility testing; and A sore and scratchy throat and/or pain on swallowing (odynophagia) together with at least 2 of the following clinical signs Tonsil and/or pharyngeal erythema and/or exudate Cervical adenopathy Uvular edema Fever  Symptoms that collectively suggest nonstreptococcal T/P (eg, laryngitis, coryza, conjunctivitis, diarrhea, cough) History of positive throat culture for Streptococcus pyogenes in the absence of clinical signs and symptoms of T/P Infection of the deep tissues of the upper respiratory tract (eg, epiglottitis, retropharyngeal or buccal cellulitis, or abscess of the retropharynx, tonsil, or peritonsillar area) or of the suprapharyngeal respiratory tract and its connecting structures (eg, sinusitis, otitis media, or orbital/periorbital cellulitis) History of rheumatic heart disease Females of childbearing potential (ie, have reached menarche) Known congenital prolonged QT syndrome Known or suspected uncorrected hypokalemia (≤3 mmol/L [mEq/L]), or hypomagnesemia or bradycardia (<50 bpm) Myasthenia gravis Known impaired renal function, as shown by creatinine clearance ≤25 mL/min The subject
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 13.0-999.0,  Tonsillitis Pharyngitis Age equal to or over 13 years For female subjects, the following conditions are to be met Subject is premenarchal or surgically incapable of bearing children Subject is of childbearing potential and all of the following conditions are met Have normal menstrual flow within 1 month before study entry Have negative pregnancy test (urine pregnancy test sensitive to at least 50 mU/mL, and Must agree to use an accepted method of contraception throughout the study (if sexually active) Clinical diagnosis of acute tonsillitis/pharyngitis caused by Streptococcus pyogenes based on A positive result from a rapid detection test for Group A streptococcal antigen and submission of a throat swab specimen for bacterial culture, identification, and antibiotic-susceptibility testing; and A sore and scratchy throat and/or pain on swallowing (odynophagia) together with at least 2 of the following clinical signs  Symptoms that collectively suggest nonstreptococcal T/P (eg, laryngitis, coryza, conjunctivitis, diarrhea, cough) History of positive throat culture for Streptococcus pyogenes in the absence of clinical signs and symptoms of T/P Infection of the deep tissues of the upper respiratory tract (eg, epiglottitis, retropharyngeal or buccal cellulitis, or abscess of the retropharynx, tonsil, or peritonsillar area) or of the suprapharyngeal respiratory tract and its connecting structures (eg, sinusitis, otitis media, or orbital/periorbital cellulitis) History of rheumatic heart disease Known congenital prolonged QT syndrome Known or suspected uncorrected hypokalemia (≤3 mmol/L [mEq/L) or hypomagnesemia or bradycardia (<50 bpm) Known impaired renal function, as shown by creatinine clearance ≤25 mL/min Myasthenia gravis History of hypersensitivity or intolerance to macrolides, penicillins, or cephalosporins Previous enrollment in this study or previous treatment with telithromycin
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 3.0-999.0,  Pharyngitis Streptococcus Pyogenes Infection Streptococcus Pyogenes Identification sore throat at least two Centor fever > 38 deg C or history of fever enlarged cervical lymph nodes tonsillar exudate lack of cough age 3-14 years  antibiotic treatment in preceding 7 days no informed consent
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 2.0-11.0,  Dengue Virus Dengue Fever Dengue Hemorrhagic Fever Dengue Diseases Aged 2 to 11 years on the day of inclusion Subject in good health, based on medical history, physical examination and laboratory parameters Provision of Assent Form signed by the subject (for subjects ≥8 years old) and Informed Consent Form signed by the parents or another legally acceptable representative (and by an independent witness for illiterate parent[s]) Subject and parents/legally acceptable representative able to attend all scheduled visits and to comply with all trial procedures For a female subject of child-bearing potential (girls post-menarche), avoid becoming pregnant (use of an effective method of contraception or abstinence) for at least 4 weeks prior to first vaccination, until at least 4 weeks after the last vaccination Documented receipt of yellow fever vaccine since at least one month before the first vaccination  Personal or family history of thymic pathology (thymoma), thymectomy, or myasthenia For a female subject of child-bearing potential (girls post-menarche), known pregnancy For a female subject of child-bearing potential (girls post-menarche), known pregnancy or positive pregnancy test in blood sample taken at Screening Participation in another clinical trial investigating a vaccine, drug, medical device, or a medical procedure in the 4 weeks preceding the first trial vaccination Planned participation in another clinical trial during the trial Known or suspected congenital or acquired immunodeficiency, immunosuppressive therapy such as anti-cancer chemotherapy or radiation therapy within the preceding 6 months, or long-term systemic corticosteroids therapy Known systemic hypersensitivity to any of the vaccines components or history of a life-threatening reaction to the trial vaccines or to a vaccine containing any of the same substances Systemic hypersensitivity to YF vaccine or history of a life-threatening reaction to YF vaccine Chronic illness at a stage that could interfere with trial conduct or completion, in the opinion of the Investigator Current or past alcohol abuse or drug addiction that may interfere with the subject's ability to comply with trial procedures
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 16.0-999.0,  Bacteremia lip/tongue piercing for at least six month in situ  pregnancy and lactating women medication with known effects on gingival tissues antibiotic medication in the last six months or need for antibiotic prophylaxis chlorhexidine use in the last six months non-plaque induced gingival disease prior diagnosis of periodontitis
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 2.0-999.0,  Atopic Dermatitis Secondary Infection Female subjects of childbearing potential must have a negative urine pregnancy test at Baseline and practice a reliable method of contraception Secondary infection of atopic dermatitis with S.aureus or S.pyogenes as the probable causative agent An infected area less than or equal to 100 centimeters squared for subjects 18 years of age or older, or, 2% body surface area for subjects under 18 years of age Skin Infection Rating Scale score greater than or equal to 8 Able to understand and comply with the requirements of the study and sign Informed Consent/Health Insurance Portability and Accountability Authorization Forms. Subjects under the legal age of consent must also have the written informed consent of parent or legal guardian  Female subjects who are pregnant, trying to get pregnant, breast feeding or who are of childbearing potential and not practicing reliable birth control Allergic to any component of the test medication Clinical diagnosis of impetigo, folliculitis or minor soft tissue infection Use of topical antibacterial medication to the study treatment area within 1 day of Visit 1 Signs of systemic infection or evidence of abcess or cellulitis at the site to be treated Medical condition that,in the opinion of the investigator, contraindicates the subject's participation in the clinical study Recent alcohol or drug abuse is evident History of poor cooperation, non-compliance with medical treatment or unreliability Participation in an investigational drug study within 30 days of Baseline Visit
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 1.0-14.0,  Hand, Foot and Mouth Disease Clinical diagnosis of severe hand-foot-mouth disease patients according to Hand-Foot-Mouth Disease Treatment Guidelines 2010 issued by China's Ministry of Health; More than 1/3 patients should be diagnosed by etiological examination Less than 48 hours of occurrence of fever and/or occurrence of tetter or herpes Age of 1-14 years Patients or their guardians agree to participate in this study and signed the informed consent form  Complicated with other serious primary diseases in organ such as congenital heart disease, chronic hepatitis, nephritis and blood diseases, etc With history of allergies on traditional Chinese medicine Patients or their guardians suffering from Psychiatric diseases Attending other clinical studies on HFMD after diagnosed
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 18.0-70.0,  Oral Health Oral Cancer Gum Disease Submit to a 24 hour urine cotinine test which will be used to determine smoking status Meet one of the following smoking Non-smoker Does not currently smoke or has no history of smoking or using tobacco related products (cigarettes, cigars, pipe, snuff, or chewing tobacco) or smoking any non-tobacco related products and urine cotinine (less than 100 ng/mL Does not currently smoke but has quit smoking for more than 10 years and smoked less than 1 pack/day of cigarettes when they were actively smoking and has a urine cotinine (less than 100 ng/mL) Smoker Smokes habitually at least 10 cigarettes/day and a urine cotinine level of >1000 ng/mL. Cigar and pipe smokers who smoke at least 10 grams of tobacco daily are also eligible Agree to consume a standardized vitamin and mineral supplement and avoid other nutritional, dietary, or alternative medications/supplements for the duration of the study No history of malabsorptive, gastrointestinal or other metabolic disorders requiring special diet recommendations Body mass index (BMI) between 20 and 35 kg/m2  Have a known allergy to strawberries, corn, and wheat products or those who have never consumed any of these products Have active metabolic or digestive illnesses such as malabsorptive disorders (Crohn's, ileus, IBS), renal insufficiency, hepatic insufficiency, hyper or hypothyroidism, cachexia, morbid obesity, or short bowel syndrome Have a history of pituitary hormone diseases that currently require supplemental hormonal administration (thyroid hormones, ACTH, growth hormone, insulin) or other endocrine disorders requiring hormone administration Have significant loss of gastrointestinal organs due to surgery, except for appendix Have altered immunity such as chronic inflammatory disease, autoimmune disorders, cancer, anemia, hemophilia, and blood dyscrasias Heavy alcohol consumers defined as >15 glasses/week (one glass = 1.5 oz. liquor, 5 oz. wine, or 12 oz. beer) Antibiotic use in the last 6 months or on medications that will accelerate or decrease bowel motility Are receiving or in need of dental treatment during the study period Have noticeable open lesions, sores that have not healed for more than 3 months, have had any active oral lesions or maladies within the last month, or have a history of leukoplakia, tumors of the buccal cavity, throat, and lips