semaj83/ctmatch_classification huggingface dataset:
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Clostridium Difficile Infection Signed informed consent prior to any study-mandated procedure Non-pregnant females were to remain non-pregnant for 1 month after the end of the study. Female subjects of child-bearing potential must have had a negative serum pregnancy test at screening and must have used a reliable method of contraception Subjects with severe CDAD; Clostridium difficile infection (CDI) must have been microbiologically proven, using a validated enzyme-linked immunosorbent assay (ELISA) for the detection of C. difficile toxin A (TcdA) and/or C. difficile toxin B (TcdB). The severity of CDAD was assessed according to the current European Union guidelines - European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Received oral vancomycin or oral/intravenous (i.v.) metronidazole therapy for the treatment of CDAD Ability to communicate well with the investigator in the local language, and to understand and comply with the requirements of the study  Known hypersensitivity to any excipients of the drug formulation Clinical evidence of any relevant disease other than CDAD and/or existence of any surgical or medical condition that might interfere with the absorption, distribution, metabolism or excretion of the study drug Veins unsuitable for i.v. puncture on either arm (e.g., veins that are difficult to locate, access, or puncture; veins with a tendency to rupture during or after puncture) Subjects with rare hereditary fructose intolerance, glucose-galactose malabsorption, saccharase-isomaltase deficiency or previously undiagnosed diabetes mellitus Subjects who have a life-threatening condition, which may be related to CDAD or other underlying illness Any clinically relevant electrocardiogram (ECG) abnormality at screening Subjects who were unable to swallow or have difficulty swallowing Subjects with vomiting, ileus or not passing stool Likelihood of death within 72 hours from any cause Life-threatening or fulminant CDAD (White blood cell count > 30 × 10^9/L; temperature > 40 °C; or septic shock, peritoneal signs or significant dehydration)
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Clostridium Difficile Infection Adult of either gender, 18 years or older, with C. difficile infection (CDI) Diarrhea associated with C. difficile positive stool assay Within 48 hours of receiving either metronidazole for mild-moderate disease or vancomycin for severe uncomplicated disease Admitted in the hospital at the time of enrollment Ability to provide informed consent Have an understanding of study procedures Ability to comply with study procedures for the entire length of the study  Hypotension or shock Megacolon or moderate to severe ileus Acute abdomen Severe leukocytosis (WBC > 20,000 cells /µL) Admission to intensive care unit on enrollment Inability to tolerate oral medication Other known etiology of diarrhea (e.g. other enteric pathogen, other intestinal disease) Inflammatory bowel disease (e.g. Crohn's disease, ulcerative colitis) Enrollment in another investigational drug trial Currently receiving other alternative treatment for CDI (e.g. antibiotics other than metronidazole or vancomycin; probiotics; immunoglobulin therapy; fecal transplant)
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 65.0-999.0,  Clostridium Difficile Colitis History of hospitalization in recent year, residence of a nursing home or institutions Expected more than 48 hours hospitalization  Colitis/ diarrhea Rectal swab performed ≥48 hrs post arrival to hospital
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 16.0-999.0,  Abdominal Pain >= 16 y abdominal pain as the main complaint  none
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-89.0,  Diarrhea Inpatient adult males and females who are at least 18-89 years of age, undergoing treatment with antibiotics irrespective of indication and the type of antibiotics  Diarrhea on admission or within the preceding week Reported recurrent diarrhea Bowel pathology that could result in diarrhea (including preexisting Inflammatory Bowel disease{IBD}, all forms for colitis or any other condition resulting in preexisting diarrhea) Intake of high risk antibiotics (clindamycin, cephalosporins, aminopenicillins→ well known to cause CDAD) and or more than two courses of other antibiotics in the past four weeks to pre-existing diarrhea associated with antibiotic use Immunosuppression (Chronic steroid use, Active chemotherapy, Active radiotherapy, HIV or any other disorder resulting in a compromise in participants immune status) Bowel surgery causing liquid stools Regular probiotic intake before admission Lactose intolerance or intolerance to dairy products
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 16.0-999.0,  Clostridium Difficile Infection Test positive for CDI on stool analysis Inpatient at Barts Health NHS Trust at time of diagnosis  Nil specific
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-90.0,  Clostridium Difficile Infection Informed consent Clinical diagnosis of CDAD plus laboratory diagnostic test No more than 24 hrs antimicrobial treatment for current CDAD episode No more than 3 episodes of CDAD in prior 12 months No previous episode of CDAD within 30 days of study enrollment Female subjects of childbearing potential must use adequate contraception  Life-threatening or fulminant colitis Concurrent use of antibiotics or any other treatments for CDAD History of inflammatory bowel disease (ulcerative colitis, Crohn's disease) Participation in other Clinical research studies within one month of screening
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 50.0-80.0,  Stroke Patients admitted to neurological department with stroke signs om CT or MRI or history consistent with stroke and gives clopidogrel 75 mg as prophylactic treatment  cancer diagnosis Other anti platelet treatment
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Ulcerative Colitis Males and females 18 years of age Diagnosis of ulcerative colitis established by previous endoscopies, with histology and clinical course consistent with diagnosis Colitis must extend for more than 15 cm above the anal verge, and involve at least the rectosigmoid Mild to moderately active ulcerative colitis defined by a minimum score of 3 and a maximum score of 8 on the 12 point Mayo scale. Mayo scores are assigned by (1) stool frequency, (2) rectal bleeding, (3) endoscopic findings and (4) physician's overall assessment of disease severity At least one previous episode of ulcerative colitis, prior to the current episode Duration of current symptomatic episode less than 4 weeks Ability to give valid informed consent For females of childbearing potential, a negative pregnancy test  Crohn's disease or pouchitis Current infectious enteritis Use of oral steroids within the last 4 weeks of the screening visit Use of antibiotics within the last 2 weeks of the screening visit Change in dose of oral 5-ASA products within the last 2 weeks of the screening visit Topical 5-ASA or steroids within 7 days prior to the baseline endoscopy Use of immunosuppressive or biological agent within 3 months of screening Use of one week before screening Use of anti-diarrheal drugs within the last 1 week of the screening visit Use of probiotic preparations either prescribed or over-the-counter within two weeks of screening
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  C-difficile Patients must be 18 years of age or older 2. Patient must have a positive C. difficile test within the 10 days prior to the procedure 3. Continued symptoms of c-difficile infection 4. Patients must have failed at least two courses of appropriate antibiotic therapy for C. diff to be a candidate for this procedure -  Under 18 years of age 2. Negative C. difficile test within the 10 days prior to the procedure 3. No symptoms of c-difficile infection 4. Less than two courses of appropriate antibiotic therapy for C. difficile infection
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Irritable Bowel Syndrome With Diarrhea At screening Female patients aged 18 years or older Clinical diagnosis of IBS-D according to the following symptoms-based as per Rome III modular questionnaire 1. Recurrent abdominal pain or discomfort for at least 3 days per month in the last 3 months associated with at least 2 of the following characteristics: a) improvement with defecation; b) onset associated with a change in the frequency of stool; c) onset associated with a change in form (appearance) of stool. 2. Symptom-onset at least 6 months prior to diagnosis. 3. Loose or watery stools at least 25% of the time in the last 3 months AND hard or lumpy stools less than 25% of the time in the last 3 months. 4. Additional criterion: more than 3 bowel movements per day at least 25% of the time in the last 3 months For patients older than 50 years OR patients with a positive family history of colorectal cancer: normal results from colonoscopy/flexible sigmoidoscopy performed within the last 5 years For patients aged 65 years or older: absence of ischaemic colitis, microscopy colitis or any other organic gastrointestinal disease as evidenced by the results of a colonoscopy/flexible sigmoidoscopy with biopsy performed within 6 months For women of childbearing potential: Use of a highly effective contraceptive method with a failure rate <1% per year throughout the entire study period Physical examination without clinically relevant abnormalities during screening No clinically relevant abnormalities in 12-Lead ECG or in laboratory findings Mentally competent, able to give written informed consent, and compliant to undergo all visits and procedures Unrestricted access to a touch-tone telephone  Male gender Diagnosis of IBS with a subtype of constipation, mixed IBS, or un-subtyped IBS Colonic or major abdominal surgery, any other major abdominal surgery or elective major surgery planned or expected during the study History of organic GI abnormalities, inflammatory bowel diseases, complicated diverticulosis, ischaemic colitis, microscopic colitis History of pancreatitis, active biliary duct disease, cholecystitis or symptomatic gallbladder stone disease in the previous 6 months History of gluten enteropathy or lactose intolerance Current or previous diagnosis of neoplasia History of endometriosis History of positive tests for ova or parasites, or clostridium difficile toxin or occult blood in the stool in the previous 6 months History of human immunodeficiency virus infection
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Clostridium Difficile Colitis Study entry is open to adults (>18 years old) who have had three of more episodes of Clostridium difficile colitis within the previous 12 months  Absolute neutrophil count < 500 cells/mm3 Active infection at other sites (excluding Clostridium difficile) requiring ongoing antibacterial therapy (antiviral or antifungal therapy is acceptable) Current or planned cytotoxic chemotherapy within 14 days of the potential fecal transplantation date Life expectancy <180 days Diagnosis of inflammatory bowel disease (e.g. Crohn's or ulcerative colitis) Inability to swallow capsules Indwelling nasogastric, orogastric, gastrostomy, or jejunostomy tube History of partial or total gastrectomy Short gut syndrome requiring total parenteral nutrition Pregnancy
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Antibiotic-associated Diarrhea Clostridium Difficile Receiving antibiotics for not more than 48 hours prior to enrollment and free from diarrhea able to understand and sign informed consent and HIPPA available throughout the study period subjects should have the mental ability to understand and willingness to fulfill all the details of the protocol  three or more soft and unformed or watery stools per day at admission receiving chemotherapy or radiation therapy diagnosis of inflammatory bowel disease NPO without PO meds neutropenia (an absolute neutrophil count (ANC) of less than 1500/microL) HIV positive with a CD4+ T-lymphocyte count <400 per mcL blood requiring care in an intensive care unit status-post bowel resection during hospitalization patient's receiving antibiotics four weeks prior to hospitalization patient with severe life threatening illness or immunocompromised
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 2.0-21.0,  Clostridium Difficile Recipient Documented laboratory-confirmed clostridium difficile infection Documentation of ongoing diarrhea at time of recruitment Children ≥2 years old, <18 years old; young adults >18 years old, <21 years old Undergoing clinically-indicated colonoscopy Recurrent c-diff infection (three or more occurrences) Donor First-degree relative recommended, but not compulsory ≥ 18 years old In good health No antibiotic use within the last 90 days  Recipient Severe comorbid condition (at discretion of the principal investigator) On immunosuppressive medications (high dose steroids 30 mg/kg of methylprednisolone) Severe or fulminant C. difficile colitis Toxic appearance Signs of hemodynamic instability Peritoneal signs on physical exam Anemia on complete blood count electrolyte imbalances on basic metabolic panel Considerations for Increased Risk of Adverse Events Should Be Given to patients with decompensated liver cirrhosis, advanced HIV/acquired immune deficiency syndrome, recent bone marrow transplant, or other cause of severe immunodeficiency
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Organophosphate Poisoning Male (females usually wear national dresses considered to provide adequate protection (43) Age min. 18 years (implies being a legal worker) Grows crops in knee and abdomen height in given data collection period Willing to spend 1.5-3 hours working with organophosphates under normal working conditions Involved in farming minimum two years (implies being active) Usually sprays at least once in two weeks with organophosphates on average (implies being active) Uses a hand pressured backpack sprayer placed at home (necessary to complete non-intervention) Works with crops in 5-10 katha land (sufficient to apply organophosphates for given time) Has a mobile/landline number (necessary for easy contact) Has a helper during work with organophosphates (organophosphate exposure reduced)
Patient description: The patient is a 60-year-old woman admitted to the stroke department with a recent history of a second course of intravenous antibiotics for aspiration pneumonia. She is febrile and complained of abdominal pain and diarrhea (bowel movements eight times in 3 hours, large volumes of greenish, liquid stool each time). The patient's abdomen is generally tender and distend with hyperactive bowel sounds. She is febrile (38.4°C), tachycardic (113/min) and hypotensive (80/40 mmHg). The stool samples must were positive for Clostridium difficile toxin.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Abdominal Pain emergency department's patients undergoing CT evaluation for acute abdominal pain and tenderness (acute is defined as onset of current episode within 7 days of emergency department presentation)  neurological disorders altered mental status history of intra-abdominal surgery in the past 30 days BMI higher than 35 immunocompromised patients abdominal trauma in the past 30 days CT is ordered for the following indications isolated vomiting fever without source staging of malignancy