semaj83/ctmatch_classification huggingface dataset:
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 18.0-45.0,  Healthy Be in the age range of 18.45 years Be neither overweight nor underweight for his/her height as per the Life Insurance Corporation of India height/weight chart for non-medical cases Have voluntarily given written informed consent to participate in this study Be of normal health as determined by medical history and physical Examination of the subjects performed .within 28 days prior to the commencement of the study If female and Of childbearing potential, is practicing an acceptable method of birth control for the duration of the study as judged by the investigator(s), such as condoms, foams, jellies, diaphragm, intrauterine device (IUD), or abstinence; or~ Is postmenopausal for at least 1 year; or Is surgically sterile bilateral tubal ligation, bilateral oophorectomy, or hysterectomy)  History of allergy to metformin and other related antidiabetic biguanide preparations Any evidence of organ dysfunction or any clinically significant deviation from the normal, in physical or clinical determinations Presence of disease markers of HIV 1 and 2, Hepatitis B and C viruses and syphilis infection Female volunteers demonstrating a positive pregnancy screen Female volunteers who are currently breastfeeding Presence of values' which are clinically significantly different from normal reference ranges for hemoglobin, total white blood cells count, differential WBC count and platelet count Positive for urinary screen testing of drugs of abuse (opiates and cannabinoids Presence of values which are significantly different from normal.reference ranges (as defined in Appendix 5) for se rum creatinine, blood urea nitrogen serum aspartate aminotransferase (AST), serum alanine aminotranferase (ALT), serum alkaline phosphatase, serum billrubin, plasma glucose and serum cholesterol Clinically abnormal chemical and microscopic examination of urine defined as presence of RBC, WBC (>4/HPF), epithelial cells (>4/HPF), glucose, (positive) and protein (positive)
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Acute Kidney Insufficiency Acute Renal Insufficiency Acute Kidney Injury Ischemic Preconditioning Patient undergoing heart surgery on cardiopulmonary bypass  Known peripheral vascular disease of the lower extremities associated with active skin necrosis or infection End-stage renal disease Inability to give informed consent
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 0.0-0.082,  Congenital Heart Disease Disorder of Fetus or Newborn Neonates Age </= 1 month Scheduled to undergo cardiac surgery involving Cardiopulmonary Bypass (CPB) (reparative or palliative procedures) Inpatient Status at MUSC a minimum of 8 hours prior to planned surgery  Prematurity: </= 36 weeks post gestational age at time of surgery Treatment with steroids, other than inhaled forms, in the two weeks prior to scheduled surgery Participation in research studies involving the evaluation of investigational drugs within 30 days of randomization Suspected infection that would contraindicate steroid use (eg Herpes) Known hypersensitivity to IVMP or one of its components or other contraindication to steroid therapy (e.g., gastrointestinal bleeding) Preoperative use of mechanical circulatory support or active resuscitation at the time of proposed randomization Inability to begin the pre-operative study drug at least 8 hours prior to surgery
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 18.0-55.0,  Healthy Study subject must have read, understood and provided written informed consent and HIPAA authorization after the nature of the study has been fully explained Be > or equal to 18 years of age and < or equal to 55 years of age Be in general good health without history of any of the conditions listed in  No use of any tobacco products for at least 6 months A woman must agree not to become pregnant from the time of study enrollment until at least 3 months after the completion of the monoclonal antibody infusion. If a woman is sexually active and has no history of hysterectomy or tubal ligation, she must agree to use hormonal or barrier birth control with spermicidal gel Sexually active male subjects must use a barrier method of contraception during the course of the study Screening laboratory values must meet the following WBC (>3,900 <11,000/mm^3) Platelets(>100,000/mm^3) Hemoglobin (>10.5 gm/dl) Creatinine (<1.1 x ULN) BUN (<1.25 x ULN)
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 0.0-0.019,  Adrenal Insufficiency All preterm (28 to 34 week gestation) very low birth weight (birth weight 750-1500grams.) infants born at AIIMS would be eligible for enrollment in the study. Of these infants, those who meet the following would be enrolled Cases: Preterm (28 to 34 week gestation) infants with birth weight between 750 and 1500 grams with shock in the first week of life requiring vasopressor therapy (dopamine or dobutamine or both in a dose of > 10 mcg/kg/min) Controls: Stable preterm (28 to 34 week gestation) infants with birth weight between 750 and 1500 grams who are matched for gestational age, birth weight, postnatal-age  Major congenital malformations Mother receiving anticonvulsant / anti-tubercular drugs (rifampicin, isoniazid) Postnatal corticosteroid treatment Refusal to give consent
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Premature Newborn Necrotizing Enterocolitis Premature infants with gestational age between <32 weeks regardless of birth weight  Inborn errors of metabolism Need for exchange transfusion Multiple congenital anomalies Renal failure (defined as urine output <1ml/k/h >24h, creatinine >1.8, or diagnosis of "non-oliguric renal failure" as determined by Pediatric nephrology)
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Minimal Change Disease from 18yrs to 80 yrs , man and women Minimal change disease is diagnosed by kidney biopsy On screening, the patient shows that the level of urine protein/creatinine ratio is over 3.0 On screening, the patient shows that the serum albumin is below 3.0g/dL the patient sign on the concent form  the patient have experience to take tacrolimus or cyclosporin for 1 month If it is the relapse of the nephrotic syndrome, before relapse, the maintenance dose of steroid is over 0.3 mg/kg/day steroid dependent or steroid resistant or frequent relapse case uncontrolled hypertension pregnancy or anticipate pregnancy with 6 month hypersensitivity to tacrolimus or macrolide acute hepatitis or the level of AST or ALT is over 2 times of normal range or the level of bilirubin is over 2.0 mg/dL
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Spinal Cord Injury years or older Male signed informed Consent Neg. urine multistix  Abnormalities diseases or surgical procedures performed in the lower urinary-tract
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Hepatorenal Syndrome Type 1 Written informed consent by subject or legally authorized representative At least 18 years of age Cirrhosis and ascites Rapidly progressive reduction in renal function characterized by SCr ≥ 2.5 mg/dL Doubling of SCr within 2 weeks (or for observations of shorter duration, SCr values over time meeting slope-based for proportional increases likely to be representative of at least a doubling within 2 weeks No sustained improvement in renal function (< 20% decrease in SCr and SCr ≥ 2.25 mg/dL) 48 hours after both diuretic withdrawal and the beginning of plasma volume expansion with albumin Note: Albumin doses recommended by the IAC are 1 g/kg on the first day (Maximum 100 g) and 20 g/day thereafter as clinically indicated.It is recommended (if clinically appropriate) that the albumin dose is kept constant during the study drug administration period Note: The qualifying SCr value is the SCr value at least 48 hrs after both diuretic withdrawal (if applicable) and the beginning of albumin fluid challenge. The qualifying SCr value must be ≥ 2.25 mg/dL AND at least 80% of the diagnostic (pre-fluid challenge) SCr value  Serum creatinine > 7 mg/dL Shock Note: Hypotension (Mean Arterial Pressure < 70 mm Hg or a decrease > 40 mm Hg in systolic blood pressure from baseline) with evidence of hypoperfusion abnormalities despite adequate fluid resuscitation Sepsis or systemic inflammatory response syndrome (SIRS) Note: SIRS: Presence of 2 or more of the following findings Temperature > 38°C or < 36°C; heart rate > 90/min; respiratory rate of > 20/min or a PaCO2 of < 32 mm Hg; white blood cell count of > 12,000 cells/µL or < 4,000/ µL Note: Sepsis: Documented infection and systemic inflammatory response syndrome < 2 days anti-infective therapy for documented or suspected infection Proteinuria > 500 mg/day Hematuria or microhematuria (> 50 red blood cells per high power field) Clinically significant casts on urinalysis, including granular casts
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 18.0-90.0,  Proteinuria Kidney Injury Chronic Kidney Disease Male and females, 18 years to 90 years old Any subject with pre-existing clinical indication of a kidney biopsy including, but not limited to, nephritic syndrome, nephritic syndrome or proteinuric disease state. Additionally, kidney transplant donors will be included for purpose of obtaining control tissue Willing and able to give consent Additionally, kidney transplant donors and patients requiring nephrectomy for removal of renal mass will be included for purpose of obtaining control tissue  Subjects on longstanding immunosuppressive agents (empiric initiation of glucocorticoid therapy within 48 hours prior to kidney biopsy is acceptable) Kidney transplant recipient Inability to follow-up for future protocol laboratory evaluation
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 0.0-1.0,  Peritoneal Lesion term neonates and infants undergoing heart surgery with cardiopulmonary bypass parents received written information  preoperative documented kidney injury parents not informed, opposed
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 18.0-50.0,  Polycystic Kidney, Autosomal Dominant Males and females, 18 to 50 years old at the time of consent Documented diagnosis of ADPKD (PKD-1 or PKD-2 genotypes allowed) Total kidney volume ≥ 750 cc, as measured by centrally evaluated MRI  eGFR < 60 mL/min/1.73m2 Uncontrolled hypertension (defined as systolic blood pressure ≥140 or diastolic blood pressure ≥90 mm Hg) Any previous exposure to the bosutinib test article or receipt of other polycystic kidney disease (PKD) therapies
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 0.0-24.0,  Ductus Arteriosus, Patent Gestational age <29 weeks; an echocardiographic evidence of significant PDA; an age of 12 to 24 hours; and RDS necessitating respiratory support  Major congenital anomalies; life-threatening infection or hydrops fetalis; pulmonary hypertension; death before the conclusion of the first course of ibuprofen; urine output below 1 ml per kilogram of body weight per hour during the preceding 12 hours (with the exception of the first dose); a serum creatinine concentration of >1.5 mg/dL (129 μmol per liter); a platelet count of <50,000/mm3; a tendency to bleed, as revealed by hematuria, blood in the endotracheal aspirate, gastric aspirate, or stools, and oozing from puncture sites
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 0.0-18.0,  Congenital Heart Disease Cardiopulmonary Bypass Myocardial Injury Acute Kidney Injury Acute Lung Injury Age birth to 18 years Cardiac surgery with planned cardiopulmonary bypass  Any contraindication to compression of lower extremity/extremities Body weight <2 kg Active infection going into surgery On renal replacement therapy (RRT) or mechanical circulatory support going into surgery On inotropic support going into surgery
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 0.167-1.5,  Postoperative Pain in Infants Non-prematurely-born infants admitted to hospital following surgery ages 2-18 months, studied by age group 12-18 months, 6-12 months, < 6 months  Bleeding history in infant or family Coagulopathy Gastrointestinal bleeding history Renal or hepatic disease assessed by history and by pre-drug blood tests Premature birth (<36 weeks gestation)
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 14.0-60.0,  Nephrotic Syndrome Subjects of either sex, 14-60 years of age Diagnosis of Nephrotic syndrome with hypoalbuminemia (< 3.0g/dl) and heavy proteinuria (> 3.5g/24hr) and secondary Nephrotic syndrome Refractory Nephrotic Syndrome Steroid resistant: failure to respond (either complete or partial remission) after a course of 8 weeks of 1.0 mg/kg/d prednisone or equal dose of steroid therapy Steroid dependent: recurrence of nephrotic proteinuria during tapering of prednisone at a dose > 10 mg/day or within the first 2 weeks after withdrawal of prednisone Frequently recurrence: initial remission with steroid induction therapy, but relapsed 2 or more in 6 months or 3 or more within 12 months Failure to respond (either complete or partial remission) even after CTX, MMF or CsA therapy combined with steroid eGFR ≥ 60 ml/min/1.73 m2 Provision of written informed consent by subject or guardian  Systemic disease eGFR < 60ml/min/1.73m2 Diagnosed DM Malignant tumors (except fully cured basal cell carcinoma) Familial nephritic syndrome History of significant gastrointestinal disorders (e.g. severe chronic diarrhea or active peptic ulcer disease) within 3 month prior to enter this study Any Active systemic infection or history of serious infection within one month of entry or known infection with HIV, hepatitis B, or hepatitis C Known hypersensitivity or contraindication to tacrolimus, corticosteroids Participation in another clinic trial and/or receipt of investigational drugs within 4 weeks prior to screening Pregnancy, nursing or use of a non-reliable method of contraception
Patient description: A 6-month-old male infant has a urine output of less than 0.2 mL/kg/hr shortly after undergoing major surgery. On examination, he has generalized edema. His blood pressure is 115/80 mm Hg, his pulse is 141/min, and his respirations are 18/min. His blood urea nitrogen is 33 mg/dL, and his serum creatinine is 1.3 mg/dL. Initial urinalysis shows specific gravity of 1.017. Microscopic examination of the urine sample reveals 1 WBC per high-power field (HPF), 18 RBCs per HPF, and 5 granular casts per HPF. His fractional excretion of sodium is 3.3%.

Clinical trial eligibility criteria: eligible ages (years): 0.0-18.0,  Kidney Failure, Acute Age < 18 years, including the newborn  Acute kidney injury as defined by pRIFLE classification requiring extra renal replacement therapy, whatever is the method  Treatment by extra renal replacement therapy for terminal renal failure History of renal transplantation Extra renal replacement therapy for an inborn errors of metabolism without acute renal failure Extra renal replacement therapy in the context of a drug intoxication without acute renal failure Treatment by technique in MARS (Molecular Adsorbent Recirculating System) Modified ultrafiltration during surgery