Patient description: The patient is a 37-year-old woman who came to the clinic for a routine Pap smear. The test revealed stage 1B of cervical cancer. The patient tested positive for HPV 16. She has three sexual partners and four children. She underwent tubal ligation. She smokes 30 packs/year and drinks alcohol frequently. She is otherwise healthy. She was offered a radical hysterectomy.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Cervical Cancer Written informed consent. 2. Histological diagnosis of squamous cell carcinoma, adenocarcinoma or adenosquamous cell carcinoma of the cervix. Not accepted are small cell, clear cell and other rare variants of the classical adenocarcinoma. 3. Histologically confirmed, Stage IB-IVB, invasive cervical carcinoma associated with HPV 16 and/or 18 and meet the following for either Cohort 1 or Cohort 2. 1. Cohort 1 Newly diagnosed inoperable cervical cancer treated with chemoradiation therapy with curative intent and life expectancy of at least 12 months as assessed by the investigator No CNS/spinal metastases Able to initiate study treatment within 2 weeks of completion of last chemoradiation treatment 2. Cohort 2 Persistent and/or recurrent cervical cancer No CNS/spinal metastases Able to initiate study treatment at least 2 weeks but no more than 4 weeks after completion of salvage therapy Life expectancy of at least 12 months as assessed by the investigator 4. Electrocardiogram (ECG) with no clinically significant findings. 5. Chemistry, liver function tests, renal function, total CPK and hematology lab results must be ≤ Grade 1 at the time of screening. 6. Eastern Cooperative Oncology Group (ECOG) Performance status of ≤ 1. 7. Adequate venous access for repeated blood sampling according to the study schedule. 8. Women of child-bearing potential must have a negative serum pregnancy test and agree to remain sexually abstinent, have a partner who is sterile (i.e., vasectomy), or use two medically effective methods of contraception (e.g., oral contraception, barrier methods, spermicide, intrauterine device [IUD]). 9. Able and willing to comply with all study procedures  Pregnancy or breastfeeding. 2. History of previous therapeutic HPV vaccination. 3. Prior exposure to an investigational agent or device within 30 days of signing the ICF. Of note, the participant may participate in observational studies. 4. Positive serological test for HIV, Hep B or Hep C or history of HIV infection, Hepatitis B or Hepatitis C (women with cured HCV will be allowed; participant must have had a serologic test performed within 12 months of informed consent). 5. Prior major surgery from which the participant has not yet recovered to baseline. 6. High medical risks because of non-malignant systemic disease or with active uncontrolled infection. 7. Current malignancies at other sites, with the exception of adequately treated basal or squamous cell carcinoma of the skin. 8. Congestive heart failure or prior history of New York Heart Association (NYHA) class III/ IV cardiac disease. 9. Use of topical corticosteroids at or near the intended administration site. 10. Any cardiac pre-excitation syndromes (such as Wolff-Parkinson-White). 11. History of seizures (unless seizure free for 5 years). 12. Tattoos or scars within 2 cm of the intended site of injection or if there is implanted metal within the same limb. Any device implanted in the chest (e.g., cardiac pacemaker or defibrillator) excludes the use of the deltoid muscle on the same side of the body. 13. Active drug or alcohol use or dependence. 14. Imprisonment or compulsory detainment for treatment of either a psychiatric or physical (i.e. infectious disease) illness. 15. History of immunosuppressive or autoimmune disease. 16. Any other illnesses or conditions that in the opinion of the investigator may affect the safety of the participant or limit the evaluation of a participant or any study endpoint