semaj83/ctmatch_classification huggingface dataset:
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 0.083-15.0,  Invasive GAS Infection Age ≥ 1 month to <15 years at the time of Group 1 : Children hospitalized for invasive GAS infection Subgroup 1A ( N = 75 ): Children with invasive infection without known risk factor  Subgroup 1B (N = 75) : Children with invasive infection with known risk factor  GAS Invasive infections are defined by a) Proved infection : Bacteriological isolation of S. pyogenes from a liquid or a normally sterile site, except from a blister of a simple erysipelas, without necrosis . This is sometimes associated with a shock with multiorgan failure (streptococcal toxic shock syndrome ( STSS )) b ) Probable infection  . Bacteriological isolation of S. pyogenes from a normally non-sterile site ( eg skin, upper respiratory tract ) associated with extensive soft tissue necrosis . Bacteriological isolation of S. pyogenes a site or a biological sample usually non-sterile ( eg skin , upper respiratory tract ) associated with a evocative shock syndrome STSS and no other cause found  Contributing factors for invasive infection are defined by cutaneous effraction (wounds , burn , chicken pox ), the use of corticosteroids or other treatment, immunosuppressive and recent surgery  Group 1: Children with a known immune deficiency unrelated to the risk factors described above Group 2: Children with a known immune deficiency
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 10.0-999.0,  Kawasaki Disease Aneurysm, Coronary Clinical diagnosis of Kawasaki Disease with giant aneurysm Must be older than 10 years old  Subjects ever received coronary artery bypass graft (CABG) surgery Subjects have active hepatitis or persistent abnormal liver function such as elevated GOT and GPT Subjects have the past history of rhabdomyolysis Female subjects are pregnant or plan for child-bearing during study periods
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Kawasaki Disease (both 1 and 2) All subjects are children who fulfilled the for Kawasaki Disease (American Heart Association criteria) Fever > 5 days, and 4 of the 5 following symptoms Diffuse mucosal inflammation (strawberry tongue, dry and fissured lips) Bilateral non-purulent conjunctivitis Dysmorphous skin rashes Indurative angioedema over the hands and feet Cervical lymphadenopathy. (One or more nodule at lease 1.5 cm in diameter) 2. KD patients are treated with IVIG at each hospital after informed contents are obtained  Patients whose symptoms did not full fit the Kawasaki Disease criteria Had an acute fever for < 5 days and >10 days Incomplete collection of each followed-up data (CBC/DC, GOT/GPT, BUN/Cr, Albumin, ESR, C-Reactive Protein, 2D echocardiography) IVIG treatment at other hospital before refers to study centers Treatment with corticosteroids, other than inhaled forms, in the previous 2 weeks before enrollment The presence of a disease known to mimic Kawasaki disease Previous diagnosis of Kawasaki disease Inability to take aspirin
Patient description: A 4-year-old girl presents with persistent fever for the past week. The parents report a spike at 104F. The parents brought the child to the emergency room when they noticed erythematous rash on the girl's trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites of both eyes are red with no discharge.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Cirrhosis Coagulopathy Patients 18 and older, admitted to the hospital Patients who have clinically documented cirrhosis Patients who are coagulopathic (INR > 1.5 and/or platelets < 50,000) Patients undergoing an endoscopic procedure or neurosurgical procedure  Patients must not be pregnant Patients must not be taking any anticoagulant or antiplatelet medication (with the exception of ASA 81 mg or heparin for DVT prophylaxis) Patients must not have an active infection (per PI discretion) Patients must not have any known hemostatic disorder
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 50.0-80.0,  Osteoporosis 80 years of age, inclusive years since last menses Dx femoral neck osteoporosis No vertebral fractures  Poor candidate for study drugs Hx of diseases affecting bone metabolism Hx of breast/estrogen-dependent cancer Current use of osteoporosis drug therapy Hx/high risk of VTE
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Small Cell Lung Cancer Written informed consent (patient's written understanding of and agreement to participate in this study) Patients with confirmed extensive small cell lung cancer (SCLC) No prior chemotherapy within 5 years of the diagnosis of SCLC Presence of either measurable or non-measurable SCLC by X-ray or physical examination At least 3 weeks since last major surgery (a lesser period is acceptable if decided to be in the best interest of the patient) At least 24 hours since prior radiotherapy. Patients who have received radiotherapy must have recovered from any reversible side effects, such as nausea and vomiting Laboratory Patients must have adequate bone marrow reserve and adequate kidney and liver function  Symptoms of spreading of the disease to the brain that requires treatment with drugs called steroids Any active infection Severe medical problems other than the diagnosis of SCLC, that would limit the ability of the patient to follow study guidelines or that would expose the patient to extreme risk Ongoing or planned chemotherapy, immunotherapy, radiotherapy, or investigational therapy for the treatment of SCLC Use of an investigational drug within 30 days before the first dose of study medication Women who are pregnant or lactating Patients of child-bearing potential who refuse to practice an adequate form of birth control Patients with clinical evidence of any stomach or intestinal (GI) condition Patients requiring treatment with the drug cyclosporin A
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Sepsis Adult patients with severe sepsis Presence of a suspected or proven infection One or more sepsis-associated organ failure  Are indicated for the treatment with drotrecogin alfa (activated) in the investigative site country Are contraindicated for treatment with drotrecogin alfa (activated) under the applicable label in the investigative site country Platelet count <30,000/mm3 Are receiving therapeutic heparin
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 10.0-50.0,  Pneumothorax All patients requiring VATS caused by recurrent, persistent, or contralateral spontaneous pneumothorax as well as by spontaneous hemopneumothorax were eligible for this study  greater than 50 years of age, with underlying pulmonary disease, previous ipsilateral thoracic operation, allergy to tetracycline or minocycline, and unwilling to receive randomization
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Critical Illness Deep Venous Thrombosis Patient is >/= 18 years of age Actual body weight is >/= 45 kg Admission to ICU expected to be >/= 72 hours in duration  Neurosurgery within last 3 months Ischemic stroke within last 3 months Intracranial hemorrhage within last 3 months Systolic Blood Pressure >/= 180mm Hg, Diastolic Blood Pressure >/= 110mm Hg for >/= 12 hours requiring vasoactive drug infusion Major hemorrhage within last week unless definitively treated Coagulopathy as defined by INR >/= 2 times upper limit of normal [ULN], or PTT >/= 2 times ULN, at time of screening Thrombocytopenia defined as platelet count </= 75 x 109/L, at time of screening Other heparin contraindications (e.g., HIT, pregnancy, lactating) Contraindication to blood products (e.g., Jehovah's Witness) Unable to perform lower limb ultrasound (e.g., bilateral above the knee amputation, or severe distal extremity burns)
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Critically Ill Deep Venous Thrombosis Admission to ICU Men and women greater than 18 years of age or older Expected to remain in ICU admission greater than 72 hours  Contraindications to LMWH or blood products Trauma, post orthopedic surgery, post cardiac surgery or post neurosurgery patients Uncontrolled hypertension as defined by a systolic blood pressure > 180 mmHg or a diastolic blood pressure > 110 mmHg Hemorrhagic stroke, DVT, PE or major hemorrhage on admission or within 3 months Coagulopathy as defined by INR >2 times upper limit of normal [ULN], or PTT >2 times ULN Renal insufficiency as defined by a creatinine clearance <30ml/min A need for oral or intravenous or subcutaneous therapeutic anticoagulation Heparin allergy, proven or suspected heparin-induced thrombocytopenia (HIT) Receipt of >2 doses of UFH or LMWH in ICU Pregnant or lactating
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 16.0-999.0,  Deep Vein Thrombosis Pulmonary Embolism Age > 16 years Unilateral or bilateral, closed or open, fractures of the lower extremity distal to the knee including Isolated fractures of the tibia including tibial plateau, shaft and plafond and medial malleolus Isolated fractures of the fibula including fibular head, fibular diaphysis,distal fibula and lateral malleolus Combined fractures of the tibia and fibula Tibia and/or fibula fractures may be accompanied by fractures of the patella and/or foot as well as ligamentous injuries as long as either the tibia or the fibula is involved Patients must be scheduled to undergo surgery (internal or external fixation) for repair of their fracture during the current admission  Patients presenting greater than 72 hours after injury Major injury involving other site(s) Lower extremity vascular injury requiring surgical repair Known systemic bleeding disorder or INR > 1.5, aPTT > 40 sec, or platelets < 50 x 109/L at baseline Active, uncontrolled bleeding (as determined by the attending surgeon or delegate) Intracranial or other major bleed in the previous 4 weeks Ongoing need for anticoagulation for other reasons Previous DVT or PE (objectively proven or treated with anticoagulants) Known molecular hypercoagulable state Active cancer
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Quality of Health Care Pulmonary Embolism patient with suspected pulmonary embolism prescription of a specific paraclinical diagnostic investigation or start of a specific treatment for pulmonary embolism  confirmation or of pulmonary embolism before admission in emergency department confirmation of deep venous thrombosis before admission in emergency department suspicion of pulmonary embolism during hospitalization (in-patient) suspicion of pulmonary embolism without investigation realization patient already included in the study patient refusing the utilization of his data for the study
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 30.0-85.0,  Total Hip Replacement Patients accepted for fast-track total hip replacement, i.e.ASA 3 or lower  Not able to speak dutch communication problems dementia mental retardation
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Deep Vein Thrombosis (must meet 1, 2 and 3) At high risk for thromboembolism (any one of the following) Age > 35 years Obesity (> 80 kg) Para &#61619;4 Gross varicose veins Current infection Pre-eclampsia Immobility prior to surgery (> 4 days) Major current disease: includes heart or lung disease, cancer, inflammatory bowel disease, and nephrotic syndrome  (must not meet any of the following criteria) Greater than 36 hours since delivery Need for anticoagulation, including Women with a confirmed thrombophilia Women with paralysis of lower limbs Women with personal history of VTE Women with antiphospholipid antibody syndrome (APLA) Women with mechanical heart valves Contraindication to heparin therapy, including History of heparin induced thrombocytopenia
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Diabetes Diabetes Mellitus, Type 2 Diagnosis of type 2 diabetes HbA1C <= 12.0% within the past 12 months BMI <= 45.0 kg/m2 Initiation, addition of, change to, or continuation of basal insulin therapy with insulin detemir as deemed necessary by Investigator  Anticipated change in concomitant medication known to interfere with glucose metabolism such as systemic steroids, non-selective beta-blockers or mono amine oxidase (MAO) inhibitors Proliferative retinopathy or maculopathy that has required acute treatment within the last 6 months Any glucose lowering medication that is not indicated in combination with insulin, such as GLP-1 Analogues Known hypoglycemia unawareness or recurrent major hypoglycemia, as judged by the Investigator
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Pulmonary Embolism Right Heart Strain Referred from clinical departments at Odense University Hospital Referred to the Departments of Nuclear Medicine or Radiology for diagnostic evaluation of suspected pulmonary embolism Referred for lung scintigraphy, spiral computer tomography, or pulmonary angiography  Age below 18 Contrast allergy Pregnancy S-Creatinine above 200 micromol/L Metformin treatment Fibrinolytic or surgical therapy between examinations No informed consent Withdrawn consent Failed logistics (more than 24 hours between examinations) No conclusive pulmonary angiography
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 40.0-999.0,  Embolism Hospitalization due to an acute non-surgical disease Significant decrease in mobility  Indication for anticoagulant or thrombolytic therapy Major surgical or invasive procedure within the 4 weeks that precede randomization Expected major surgical or invasive procedure (including spinal/peridural/epidural anesthesia or lumbar puncture) within the 2 weeks that follow the randomization Immobilization due to cast or fracture of lower extremity Immobilization lasting longer than 3 days in the period prior to randomization Heparin administration longer than 36 hours in the period prior to randomization Acute ischemic stroke Other protocol-defined inclusion/
Patient description: A 65 yo male with no significant history of cardiovascular disease presents to the emergency room with acute onset of shortness of breath, tachypnea, and left-sided chest pain that worsens with inspiration. Of note, he underwent a right total hip replacement two weeks prior to presentation and was unable to begin physical therapy and rehabilitation for several days following the surgery due to poor pain management. Relevant physical exam findings include a respiratory rate of 35 and right calf pain.

Clinical trial eligibility criteria: eligible ages (years): 16.0-999.0,  Adult Respiratory Distress Syndrome Pulmonary Hypertension After obtaining informed consent the following patients will be included All patients admitted to the ICU with pulmonary hypertension (mean PA > 35 mmHg) All patients in ICU with post operative pulmonary HTN (mean PA > 35 mm Hg) All patients with ARDS (PaO2/FiO2 < 200 arterial hypoxemia, bilateral infiltrates on Chest X-ray infiltrates on CXR and a wedge < 20 mm Hg on swan ganz parameters) or signs of heart failure  Patients to be excluded will be those with Pulmonary embolus Cor pulmonale Ejection fraction of < 30%, wedge > 20 mm Hg Non-intubated patients Pediatric patients (< 16 yrs of age)