semaj83/ctmatch_classification huggingface dataset:
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Pelvic Inflammatory Disease women admitted to Emergency with pelvic-inflammatory disease or tubo-ovarian abscess from the year range: 1995-2000
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Cervical Cancer Precancerous Condition HPV Disease Human Papilomavirus Colposcopically and biopsy confirmed grade 3 cervical intraepithelial neoplasia Human papillomavirus (HPV) 16-positive disease by PCR Measurable disease after diagnostic biopsy No concurrent adenocarcinoma in situ of the cervix Not pregnant or nursing Negative pregnancy test Fertile patients must use an effective form of contraception during study treatment Immunocompetent No concurrent malignancy, except for nonmelanoma skin lesions No serious concurrent disorder, including any of the following
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Healthy Healthy, non-smoking male or healthy, non-smoking, non-pregnant female Able to comply with study procedures Male subjects must agree to use 2 highly effective methods of contraception Female subjects must be of documented non-child-bearing potential or must agree to use 2 highly effective methods of contraception No clinically significant abnormal results for physical examination or clinically significant out of range laboratory results  History of any significant illness Illness within 5 days before Day 1 Regular treatment with any medications Any type of tobacco or nicotine use History of drug or alcohol abuse or addiction within 2 years before Screening visit Positive tuberculin skin test at Screening Female subjects who are lactating or planning to become pregnant during the study period or within 90 days of last dose of study drug
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Lesion Age > 18 years Clinical or instrumental documentation of stable/unstable myocardial ischemia or angina with a >50% lesion on a major coronary vessel and/or side branch > 2.0 mm Lesion length ≤ 20 mm Vessel requiring stent size with diameter ≥ 2.5 mm  Age < 18 years Life expectancy < 6 months Chronic renal failure (serum creatinine > 2 mg %) Ongoing acute myocardial infarction Left ventricular ejection fraction (LVEF) <30% Cardiogenic shock Documented or suspected systemic and/or infectious disease Hypersensitivity to cobalt chromium or contrast media Anti-thrombotic drug intolerance Cardiac and/or extracardiac documented disease requiring surgical repair
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 16.0-50.0,  Bacterial Vaginosis Women will be included whether their complaint is symptoms of BV and have a positive whiff test/vaginal swab or if they have a positive whiff test/vaginal swab and are then asked if they have any symptoms of BV present. The following must be met for enrolment in the study: 1. ages 16-50 and premenopausal; 2. capable of giving written informed consent; 3. English speaking; 4. negative pregnancy test on enrolment day; 5. agree to follow study protocol; 6. documented BV infection by positive vaginal swab +/ positive whiff test/pH > 4.5; 7. agree to no intercourse for the 10 days of treatment (or to use non-lubricated condoms if unavoidable); 8. agree not to douche or use any intravaginal products during treatment (including tampons, medications, devices); 9. abstain from alcohol during the 10 days of treatment (from 24 hours before through 72 hours after taking study medication); 10. agree to no new medications or antibiotics during treatment; 11. no current sexually transmitted infection as determined by history, physical exam and negative swabs for chlamydia, gonorrhea, candidiasis, trichomonas; 12. patient is reliable for follow up  The following women would be excluded from study participation: 1. less than 16 or post-menopausal; 2. negative vaginal swab regardless of whiff test/pH > 4.5; 3. menstruating at diagnosis; 4. symptoms so severe as to make allocation to placebo unacceptable to the patient; 5. currently pregnant or at high risk for pregnancy; 6. current sexually transmitted infection (HIV, hepatitis, chlamydia, gonorrhea, trichomonas, HPV or HSV); 7. current yeast infection as determined by history, physical and swabs; 8. history of PID; 9. allergy to latex or metronidazole; 10. presently lactating; 11. any open wound, excoriation, vaginal irritation and including bartholin's cyst/abscess as determined by physical exam; 12. presence of another vulvar, vaginal or medical condition, including cervical neoplasia treatment, that might confound treatment response; 13. using lithium, anti-coagulants or disulfiram drugs; 14. any antifungal or antibiotic use 14 days prior to enrolment 15. PAP smear done within one week of enrollment
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Human Papillomavirus Infection Female partners of HIM Study participants report no abnormal Pap smear during the past 6 months have not had a hysterectomy have never been diagnosed with genital warts are not pregnant residents of southern Florida are not and have not been enrolled in an HPV vaccine trial willing to comply with scheduled visits every 6 months for 2 years  Do not meet the Criteria
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Metastatic Colorectal Cancer Liver Metastases Hepatic Lesions Histologically or cytologically confirmed carcinoma of the colon and/or rectum with evidence of liver metastases (new confirmation of metastatic disease is required in case the time interval from last histological diagnosis to enrolment exceeds 3 years) Patient with wild type (WT) KRAS tumor status Patient whose liver metastases are considered to be non resectable with curative intent in medico-surgical staff meeting. In particular patients with at least one of the following which prevent complete local treatment of liver metastasis with surgery alone or surgery plus radiofrequency ablation because less than 30% estimated residual liver after resection disease in contact with liver main vessels documented progressive disease on imaging documents or doubling of serum levels of carcino-embryonic antigen (CEA) or CA19.9 over the past 90 days or less Patient with up to three resectable extrahepatic nodules of <= 10 mm One, two or three prior chemotherapy lines for colorectal cancer Written informed consent Age >=18 years  Patient whose primary tumor or metastasis displays mutation of K-Ras (codon 12 and/or 13) Unresectable extrahepatic diseases More than three resectable extrahepatic nodules Size of extra hepatic nodules > 1 cm Prior HAI of the 3 drugs More than 2 prior surgical attempts for metastatic disease Prior radiotherapy for metastatic disease Known documented intolerance or hypersensitivity to any of the drugs used Sensory neuropathy grade 3 (National Cancer Institute-Common Terminology for Adverse Events -NCI-CTCAE, Version 3.0) Past or current history (within the last 2 years prior to treatment start) of malignancy other than colorectal cancer (patients with curatively treated basal and squamous cell carcinoma of the skin or in situ carcinoma of the cervix are eligible)
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 20.0-80.0,  Cervical Cancer Healthy volunteers People infected with HPV type 16 but without CIN lesions Patients with CIN lesions Patients with cervical cancer from National Taiwan University Hospital Informed consent is obtained, and the protocols are reviewed and approved by the appropriate Investigative Review Boards  None
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Cervical Cancer Precancerous Condition Cytologically confirmed atypical glandular cells of unspecified significance Original Pap smear used to define the diagnosis must be available for review Previously enrolled by GOG-JAPAN onto clinical trialGOG-171 Must have been eligible and evaluable for the primary objective of GOG-171 Gave permission to use specimens for future cancer research in GOG-171 Underwent a loop electrosurgical excision procedure/large loop excision of the transformation zone (LEEP/LLETZ) procedure on clinical trial GOG-171 to determine the presence of cervical intraepithelial neoplasia (CIN-2 or CIN-3), significant glandular lesions (AIS), or invasive cancer Not specified PRIOR See Disease Characteristics
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-120.0,  Cervical Cancer Precancerous Condition Meets 1 of the following Underwent hysterectomy with removal of a normal cervix for diagnosis unrelated to cancer or cervical dysplasia Underwent cervical biopsy or removal of cervical tissue and diagnosed with cervical intraepithelial neoplasia (CIN) grades 1-3 Underwent cervical biopsy and diagnosed with microinvasive squamous cell carcinoma of the cervix Paraffin-embedded tissue samples of normal cervical epithelium, CIN, or microinvasive squamous cell carcinoma of the cervix must be available for examination Not specified PRIOR Not specified
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Cervical Cancer undergoing colposcopy for the diagnosis of cervical cancer LEEP for the treatment of cervical cancer in early stages Follow-up Pap smear in surveillance  Women under the age of 18 (minors) will be excluded from this study patients will be excluded if she has had a recent episode of bleeding or preterm labor Subjects who are not competent to give consent will excluded
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Lesions Patients referred to the Endocrine Consult Service with radiographic evidence of, biochemical evidence of, or histologically/cytologically proven, endocrine neoplasms, including lesions of the thyroid, parathyroid, adrenal, extra-adrenal endocrine rests, paragangliomas, neuroblastomas and pancreas Patients must have an ECOG performance score of 0-2 Patients must have laboratory and physical examination parameters within acceptable limits by standard of practice guidelines prior to biopsy or surgery Patients undergoing treatment for their neoplasm may be eligible
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Human Papillomavirus Infection Cervical Intraepithelial Neoplasia Referral to Umeå university hospital for treatment due to abnormal Pap smear  Lack of informed consent
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-64.0,  Cervical Cancer Screening HIV Infections Age 18-64 years HIV infected women due for cervical cytologic screening  Pregnancy On chronic anticoagulation medication Life expectancy of the woman is less than 1 year If the woman has had a cervical or anal pap test in the last 6 months
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 12.0-17.0,  HIV Infection HIV Infections Youth age 12-17 years For 12-15 year olds no sexual risk For 16-17 year olds (the age of lawful consent to sex in South Africa): sexually active (ever had sexual intercourse) Willing to participate in HIV testing and counseling Willing and able to assent to study Parent or legal guardian willing to provide written consent HIV-negative serostatus at screening and enrolment Females must have a negative pregnancy test at screening/enrolment Females must not be breastfeeding  for those accepting HPV vaccination Presence of any serious illness requiring treatment with systemic medications, excluding short course oral steroids or inhaled steroid treatment for asthma Contra-indication to vaccination, such as bleeding disorder Previous allergic reaction to any vaccines or to constituents of these vaccines (yeast, thimerosal or aluminum) Current immunomodulator therapy Receipt of immunosuppressor therapy (more than 10mg/day of prednisone or equivalent for >1 week) in the 6 months preceding enrollment date Receipt of any vaccine within two weeks preceding enrollment date
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Anemia Malnutrition Stunting At least 18 years of age No more than 20 wk of gestation Given Ante-natal Cards of the Ghana Health Service Completed the initial routine ante-natal examination at the clinics HIV negative or status unknown (as from the Ante-natal card) Free from chronic disease e.g. malignancy requiring frequent medical attention (as from the Ante-natal card) Residing in the Manya Krobo or Yilo Krobo district Prepared to sign an informed consent Living in the area throughout the duration of the study Acceptance of home visitors  Known asthmatic or history of allergy towards peanut or milk products Concurrent participation in another clinical trial Severe illness warranting hospital referral
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 21.0-999.0,  Human Papillomavirus Infection Female 21 years or older (ASC-US study only) Female 30 years or older (Adjunct and ASC-US studies) Subject attending a participating clinic and undergoing a Pap screening exam during the clinic visit Ability to comprehend and sign an IRB-approved Informed Consent Form  Diagnosis of cervical disease (cancer or precancerous condition) in the past 12 months Abnormal Pap test result in the past 12 months Subject under 18 years of age and consenting to the study without the presence of their parent or legal guardian Known to be pregnant Having an illness or medical condition that could interfere with or affect the conduct, results, and/or completion of the clinical trial Having an illness or medical condition that the investigator or physician feels would create an unacceptable risk to the subject if she enrolled into the clinical trial Prior vaccination for HPV
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Unsatisfactory Pap Smear A cohort of consecutive patients who received conventional Pap smear between March 2006 and August 2006 in Taichung Veterans General Hospital  nil
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  HPV16 Positive Cervical Intraepithelial Neoplasia (CIN 2/3) patients with high grade cervical intraepithelial lesions (CIN2/3) patients whose lesions are HPV16+ patients who are age 18 or older patients who are able to give informed consent patients who are immunocompetent patients who are not pregnant, committed to using adequate contraception if of childbearing age patients who have a minimum hemoglobin level of 9  Patients with cytologic evidence of glandular dysplasia Patients with cytologic evidence of adenocarcinoma in situ Patients who are pregnant Patients with an active autoimmune disease Patients who are taking immunosuppressive medication Patients with concurrent malignancy except for nonmelanoma skin lesions Patients who have an allergy to gold Patients with any evidence of damaged skin, or moles, scars, tattoos or marks at the proposed site(s) of administration that might interfere with the interpretation of local skin reactions History or evidence of a physician-diagnosed chronic or recurrent inflammatory skin disease (e.g. psoriasis, eczema, atopic dermatitis, hypersensitivity) at the proposed site of administration in the past 5 years Patients who have an active autoimmune disease or history of autoimmune disease requiring medical treatment with systemic immunosuppressants, including: inflammatory bowel disease, systemic vasculitis, scleroderma, psoriasis, multiple sclerosis, hemolytic anemic, or immune thrombocytopenia, rheumatoid arthritis, SLE, and Sjogren's syndrome, sarcoidosis. Asthma or COPD that does not require systemic corticosteroids or routine use of inhaled steroids is acceptable
Patient description: A Pap smear in a 54-year-old woman revealed abnormal cervical squamous intraepithelial/glandular lesion. She tested positive for HPV 16. She is sexually active with her husband and has 4 children. She is menopausal and uses no contraception. She smokes and drinks alcohol frequently. She is otherwise healthy. She was offered conization.

Clinical trial eligibility criteria: eligible ages (years): 18.0-50.0,  Uterine Cervical Neoplasms Cervix Intraepithelial Neoplasia women aged between 18 and 50 years old volunteers informed consent signed cervical lesion classified CIN 2 or 3, on a biopsy made during the 6 preceding weeks no sexual activity or use of effective mechanical, hormonal or intrauterine contraception (except hormonal vaginal ring)  pregnancy or breast feeding subtotal hysterectomy current or ancient renal impairment current immune disorder current use of drugs interfering with renal function current treatment for any cancer current use of treatment interfering with immunity current use of anti-viral treatment current or recent participation to another experimental study during the last 3 months before the screening visit current vaginal application of drugs or cosmetics