semaj83/ctmatch_classification huggingface dataset:
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Chronic and Acute Wounds, Diabetic Foot Ulcers and Venous Leg Ulcers Below the Knee Subjects who meet the following may be included in the clinical investigation, if they present with ALL of the following Subject is able to understand the evaluation and willing to consent and comply with all post-debridement visits and procedures Age 18 years and older. Subjects may be of either sex and of any race or skin type Subjects fulfilling any one or all of the following chronic wound(s) below the level of the knee, defined by delayed healing or cellular senescence acute wound(s) as a result of a surgical procedure, laceration, abrasion or trauma diabetic foot ulcer(s) subjects with venous leg ulcers below the knee on the leg or foot with one or more documented failure of maximal medical therapy for their study wound >30 days such as compression bandages (low elasticity, elastic, multilayered, elastic and non elastic compression) Subjects with the following lab results within 30 days of treatment serum albumin level >20g/L  Subjects will be excluded from the clinical investigation, if they present with ANY of the following Subjects that have tunneling wounds Subject presents with an active infection in the study wound, as defined by purulence and Fever and leukocytosis OR any TWO of the following Malodor, pain or tenderness, warmth, erythema, induration, swelling, lymphangitis Infected bone diagnosed by imaging modality (e.g., Magnetic Resonance Imaging (MRI) and/or radiographic images) Subjects whose study wound does not require debridement Cardiac pacemaker or other electronic implant(s) Subjects with irradiate, burn or ischaemic wounds or history of keloids
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Diabetic Foot Ulcer Is aged ≥ 18 Has diabetes mellitus, according to the American Diabetes Association (ADA) criteria Has an open foot wound with visible inflammation, namely at least 1 skin ulcer located on or below the malleolus that presents with the following clinical manifestations of a moderate or severe infection based on the Infectious Disease Society of America (IDSA) Has received appropriate surgical intervention to remove all necrotic and infected bone if diagnosed with osteomyelitis Meets certain minimal laboratory criteria  Has an ulcer infection which, based upon the patient's known history of hypersensitivity cannot be appropriately treated with at least one of the empiric systemic antibiotic regimens per protocol Has received > 48 hours of potentially effective antibiotic therapy and the wounds are clinically improving. If a patient has received an antibiotic within 72 hours, but is not improving or deep-tissue culture results indicate that the infecting pathogen is not susceptible to that antibiotic, the patient may be enrolled Requires or is likely to require treatment with any concomitant topical product or wound therapy during the study period
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Leg Ulcer Diabetic Foot Ulcer Pressure Ulcer Low to highly exuding chronic wound(wound history > 2 months) such as Leg Ulcer, Pressure Ulcer Category III to IV or Diabetic Foot Ulcer Male of female, 18 years and above Signed Informed Consent Form  Pregnancy or lactation Wound size not suitable for the wound dressing size Known allergy/hypersensitivity to any of the components in the dressing
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Post-concussion Syndrome Adults, age 18-60, both men and women Able to speak and read English as primary language Able and willing to provide written informed consent for study participation Able and willing to complete outcome assessments and provide blood and urine samples as required by the study protocol Able to tolerate the chamber environment and hood placement and to equalize middle ear pressure Past history of at least one mild traumatic brain injury with persistent symptoms that meets all of the following 1) Brain injury occurred at least 1 year but no more than 5 years prior to enrollment; 2) Brain injury occurred as an adult (at least 18 years of age); and, 3) Brain injury occurred due to non-penetrating trauma and is graded as mild At least 3 of the following persistent post-concussive symptoms from the injury: headaches, dizziness or balance problems, blurred vision, tiredness/fatigue or sleep problems, seizures, remembering things or solving problems, managing stress or emotional upsets, controlling temper/irritability, or ringing in the ears  Diabetes mellitus Uncontrolled seizure disorder (participants must be on therapy and seizure-free for at least 6 months) Claustrophobia precluding chamber or hood tolerance Implanted devices not cleared for hyperbaric pressurization Pregnancy or plans to become pregnant during the study participation period. Women of childbearing potential will be asked to use an acceptable form of birth control through the 13-week assessment visit Lung disease, such as emphysema, chronic bronchitis, asthma that is not well-controlled, or bullous lung disease, that raises the risk for pulmonary barotrauma due to air trapping Active malignancy, previous malignancy (except basal cell carcinoma) in the last 5 years, or any prior treatment with bleomycin (Blenoxane). Prior treatment with doxorubicin (Adriamycin) is acceptable as long follow-up echocardiography is normal Chronic disease such as heart or renal failure would raise the participant's risk of adverse events during hyperbaric oxygenation Prior military service in theater Alcohol abuse, by self-report, within the last year
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Varicose Ulcer Male or female over the age of 18 years Chronic venous ulceration Defined as wound of greater than four weeks in duration between the foot and the ankle with an Ankle Brachial Pressure Index greater than 0.85 Ulceration present for at least four weeks Colour venous duplex evidence of chronic venous insufficiency showing either reflux or obstruction  Acute infection in the studied lower limb within the last four weeks History of malignancy in the lower limb to be studied History of connective tissue disease Patients on medications that can cause immunosuppression Corticosteroids, chemotherapy or radiotherapy for cancer and recombinant immunological medications
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 20.0-999.0,  Pressure Ulcer Wound Necrosis over 20 years of age subject who has untreated wounds subject who has wound size over 3cm x 3cm subject who has wound over stage 2  cellulitis
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Diabetic Foot Pedal Ulcers Men or women >18 years old One or more foot ulcers without clinical evidence of osteomyelitis Diagnosis of Diabetes Mellitus* University of Texas Grade 1A, 1C, 2A, or 2C ulcer15 ABI >0.7 and Toe pressure >30mmHg  Limited life-expectancy Wounds on calf or shin that would be in contact with the TAG Brace Gangrene, active infection Osteomyelitis of the foot with the ulcer Chronically bedridden/Non ambulatory Unable to keep research appointments Wide spread malignancy or systemically immunocompromising disease Ipsilateral revascularization procedure within the last 30 days Unreliable, unwilling or unable to comprehend informed consent
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 14.0-24.0,  Diabetes Mellitus Type 1 diabetes Males and females Age between 14-24 years Any diabetes duration Cared for by the diabetes center for at least 1 year HbA1c ≥ 8% Basal bolus treatment (any insulin) Poor compliance with Self-Monitoring of Blood Glucose (less than 30% of the recommended Blood Glucose measurements recorded in the glucose meter in the two previous weeks, i.e. <16 Blood Glucose measurements in the last two weeks) Written informed consent obtained from patient or legal representative (for minor)  Treatment with other insulin regimen or Continuous Subcutaneous Insulin Infusion Refusal or inability to give informed consent to participate in the study Patients with short life expectancy Patients with conditions/concomitant diseases making them non evaluable for the primary efficacy endpoint according to physician's judgment Requirement for concomitant treatment that could bias primary evaluation Patients with high likelihood of being unavailable for 6 and/or 12 months visits Subject is the investigator, sub-investigator, research assistant, pharmacist, study coordinator, other study site staff or relative of study site staff thus considered directly involved in the conduct of the study Current addition/abuse of alcohol or drugs Severe visual or dexterity impairment Patients with any mental condition rendering them unable to understand the nature, scope, and possible consequences of the study
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-75.0,  Diabetic Foot Ulcer diabetic food ulcer classified byInternational Working Group of the Diabetic Foot (IWGDF) as grade 1 and 2  previous vascular surgery on the side that the ulcer is present uncontrolled diabetes mellitus presence of osteitis, abscess, osteomyelitis, gangrene on the side that the ulcer is present diabetic food ulcer classified byInternational Working Group of the Diabetic Foot (IWGDF) as grade 3
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 19.0-999.0,  Type 2 Diabetes Mellitus age >19 years of age type 2 diabetes mellitus requiring at least one medication (oral hypoglycemic agent and/or insulin) to control diabetes A1C ≥8% in past 1 year willingness/ability to attend the Diabetes education, dietician, and peer sessions and follow up assessments ability to provide informed consent self identify as South Asian (from India, Pakistan, Sri Lanka, or Bangladesh) regardless of generational status or timing of immigration with ability to speak in English or Punjabi  life limiting illness <12 months physical inability to exercise recurrent severe hypoglycemia or hypoglycaemic unawareness family member of, or living in same household as a participant pregnancy or gestational diabetes
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Atopic Dermatitis Eczema Male or female subjects who are not pregnant or lactating 80 years of age Diagnosis of atopic dermatitis for at least 6 months using the Hanifin and Rajka Diagnostic for atopic dermatitis Presence of lesional atopic dermatitis skin in both antecubital fossae Positive S. aureus colonization based on results of a skin culture taken from one of their AD-affected antecubital fossae during the screening visit  Use of any topical AD treatments (including topical steroids, topical calcineurin inhibitors) to either arm within one week of either screening visit Use of any oral/systemic AD therapies (antihistamines, steroids) within 28 days of either screening visit Severe AD that would worsen significantly from holding a participant's usual topical/oral AD medications for the time periods required in the inclusion/exclusion (one week prior to the screening, treatment and follow-up visits for topical medications and 28 days prior to screening, treatment and follow-up visits and for oral medications) Subjects who have taken a bleach bath within a week prior to screening, or who take bleach baths during the study Patients with severe medical condition(s) that in the view of the investigator prohibits participation in the study Subjects with Netherton's syndrome or other genodermatoses that result in a defective epidermal barrier Any subject who is immunocompromised (e.g. provides researchers with a history lymphoma, HIV/AIDS, Wiskott-Aldrich Syndrome) or has a history of malignant disease (with the exception of non-melanomatous skin cancer). This information will be gathered verbally from the patient while taking a medical history from the patient, and will not involve further testing such as an HIV test Subjects with a history of psychiatric disease or history of alcohol or drug abuse that would interfere with the ability to comply with the study protocol Active bacterial, viral or fungal skin infections Any noticeable breaks or cracks in the skin on either arm, including severely excoriated skin or skin with open or weeping wounds suggestive of an active infection or increased susceptibility to infection
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Diabetes Mellitus Diabetes Complications Diabetic Neuropathies Wound Infection an adult patient (18-80 years) suffering from infected neuropathic fore or mid-foot ulceration originated from type I or II diabetes (PEDIS-classification ≥ Grade II)  a patient whose life expectancy is less than 6 months an ulceration of ischemic or neuroischemic origin presence of systemic inflammatory response signs heel ulceration presence of osteomyelitis pregnancy known hypersensitivity to any of the ingredient including in the study or control treatment products a patient who is unable to give informed consent a patient who has an advanced malignant disease
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 5.0-18.0,  Ulcerative Colitis (UC) Informed consent Established diagnosis of UC disease Age: 5 years ( inclusive) Mild to moderate active disease, 10 ≤ PUCAI ≤45 Stable medication (IMM/ 5ASA) use for the past 6 weeks For patients who received antibiotic treatment: age 10-18 (inclusive)  Any proven infection such as positive stool culture, parasite or C.difficile Use of Antibiotics Use of steroids in the previous two weeks only Patients that are refractory to full dose steroids ( 1 mg/kg/day) Past acute severe UC Current Extra intestinal manifestation of UC Pregnancy A subset of patients who are on steroids and relapse during steroids treatment ≤0.5 mg/kg with mild to moderate disease activity will act as a second subset for this exploratory study
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Diabetic Foot Ulcers Men or women Type 1 or 2 diabetes Age ≥ 18 years Wagner 1 or 2 diabetic foot ulcer Diabetic ulcer for more than 8 weeks duration Willing to participate in the study with signed informed consent  Ankle/brachial index < 0.4 (critic ischemia) Use topical or systemic antibiotics Inability to attend to the weekly evaluations Inability to do daily ulcer cleansing Autoimmune diseases Active pharmacologic topical or systemic ulcer treatment Treatment with immunosuppressors such as steroids, radiotherapy, chemotherapy Pregnancy or lactation
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Does Hyperbaric Chaber Treatment Improve Diabetic Retinopathy Patients between ages 18-90 with Diabetes type I or II and diabetic retinopathy who are scheduled for hyperbaric treatment for other indications than DR Patients who signed an informed consent form and agree to undergo an ophthalmic physical examination, Fundus photography and OCT prior to hyperbaric treatment and oCT exam following every 10 treatments in hyperbaric chamber. Total number of hyperbaric treatments will be conducted according to the main indication for which they have been assigned this treatment  Patients with Carotid stenosis of more than 70% Anemia of < 10mg/Dl Patients with chest X ray pathology which cannot be admitted to hyperbaric chamber treatment Patients with claustrophobia or that cannot decompress properly Patients with any malignant disease Patients with inability to sign informed consent Decompression treatment will last 90 minutes in 2 atmospheres pressure with 100% oxygen
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Diabetic Foot Ulcer Patients receiving care and treatment in OUH Wound Clinic (Odense University Hospital, Denmark) with a diabetic foot ulcer Wagner groups 1 and 2 (Wagner Ulcer Classification System)  Patients with an ulcer duration of less than 2 months Ulcer area less than 0,5 x 0,5 cm (or less than 0,25 cm2) Patients who have had vascular surgery performed within the past 2 months Patients who cannot give informed consent Patients who do not read or speak danish Wagner groups 3 and 4 (Wagner Ulcer Classification System)
Patient description: 64-year-old obese female with diagnosis of diabetes mellitus and persistently elevated HbA1c. She is reluctant to see a nutritionist and is not compliant with her diabetes medication or exercise. She complains of a painful skin lesion on the left lower leg. She has tried using topical lotions and creams but the lesion has increased in size and is now oozing.

Clinical trial eligibility criteria: eligible ages (years): 21.0-999.0,  Diabetic Foot Ulcers Bacterial Infection Veterans over 21 years of age with chronic diabetic foot ulcers (wound duration over 8 weeks) who at the clinician's judgment requires wound debridement (25% or more of wound bed covered with non-viable tissue) wound size 1.5 cm (roughly the size of a quarter) or larger in diameter  Cognitive impairment that would interfere with patient signing own Informed Consent Veterans on active anticoagulant therapy with most recent (within last week) PT/INR (international normalized ratio of prothrombin time) > 3.0, or other significant bleeding risk Active immune suppression just prior to or during study (on systemic corticosteroids* within 7 days prior, or chemotherapy for cancer or RA treatment within 4 weeks prior to study, or with diagnosis of HIV/AIDS) *Nasal steroid sprays will not be excluded Active systemic antibiotics is an Absent dorsalis pedis pulses and Ankle Brachial Index (ABI) < 0.5 is an (indicates critical limb ischemia) Other possible reasons participants could be removed from this study transfers to other non-VA facilities, participant is unable to tolerate tissue sampling even with local anesthesia, and/or inability to comply with scheduled research visits. Furthermore, if the participant has significant wound healing so that sampling is not possible after the initial sampling, they will be removed from the study