semaj83/ctmatch_classification huggingface dataset:
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Perinatal Depression ≥18 years old Pregnant or 0-12 months postpartum Experiencing clinically significant depressive symptoms (defined as a score of ≥12 on the Edinburgh Postnatal Depressive Scale, EPDS, during screening) Able to access the internet on a device (i.e. mobile phone, tablet, personal computer) with video-visit capacity (including web camera and speakers) Comfortable with email communication  Active alcohol/substance use disorder in the past 12 months Active suicidal ideation Current mania or psychosis Unsuitable for virtual care, as per assessment of the treating psychiatrist
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-90.0,  Dementia Parkinson Altered Behavior in Alzheimer Disease Demyelinating Autoimmune Diseases, CNS Demyelinating Sensorimotor Neuropathy Corticobasal Degeneration Documented Functional Neurological Damage To Central or Peripheral Nervous System Unlikely To Improve With Present Standard of Care Approaches At least 6 months after onset or diagnosis of disease process Current Medical therapy for the condition is either failing or not tolerated by patient Patient must be capable of interval neurologic exams with investigators or their own neurologic specialists Patient must be capable and determined competent to provide detailed informed consent for study participation In estimation of investigators, that there are minimal or no significant risk of harm to general health or conditions for collection of autologous stem cell collection and use  Inability of patient to have diagnostic examinations or studies (MRI) to evaluate and document the disease state or unwilling/unable to cooperate with such documentation Patients not medically stable, or whom may have ongoing conditions which increases may place the patient at significant risk of major complications, to be determined by investigator or patient's medical provider or neurologic specialists History of active cancer or ongoing anticancer therapy within six months of such care Women of childbearing age must not be pregnant at the time of treatment, and should refrain from becoming pregnant of at minimum of 3 month after study treatment
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Major Depressive Disorder Traumatic Brain Injury Adults aged 18 and older 2. English language proficiency 3. Ability to provide written, informed consent; OR consent provided by legally authorized representative with assent from subject 4. Ability to see and hear (hearing or visual loss cannot impair ADLs or in-room conversation) 5. Has access to a smartphone/tablet/computer with internet and video capabilities for virtual sessions 6. Having been hospitalized for moderate to severe TBI that occurred at least 3 months prior to study entry 7. Meeting ANY ONE of the following severity as documented in electronic medical record (EPIC) or available outside records: 1. GCS 3-12 with GCS motor score ≤ 5 within 4 hours after injury 2. GCS 3-12 with GCS motor score =6 within 4 hours after injury AND documented intracranial abnormalities on imaging 3. GCS 13-15 within 4 hours after injury AND documented intracranial abnormalities on imaging 4. Loss of consciousness (LOC) > 30 min. 5. Post-traumatic amnesia (PTA) > 24 hours 8. Out of PTA at the time of enrollment (GOAT>75) 9. Clinically significant depressive symptoms: meets for Major Depressive Episode on the MINI or has a total score ≥ 23 on the Inventory of Depressive Symptomatology Clinician rated (IDS-C)  Uncontrolled medical illness 2. Behavioral dyscontrol, defined as the presence of verbally or physically aggressive behavior in the past month, as evidenced in medical records, pre-screening interviews, or observed by any study staff 3. Presents with PTSD as the primary diagnosis, as determined by a clinician 4. Substance use disorder, moderate or severe, within the past 6 months 5. Has bipolar disorder, a primary psychotic disorder or current psychotic symptoms, or acute suicidality or homicidality 6. Currently receiving regular (≥ 2 times/ mo.) psychosocial treatment for depression 7. Has participated in CBT for depression within the past 6 months 8. Individuals with history of dementia or severe cognitive impairment that is not related to TBI (e.g., cognitive impairment requiring assistance with basic activities of daily living, such as getting ready in the morning)
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Current Major Depressive Disorder Subject aged 18 to 65 Diagnosis of a characterized depressive episode assessed by the clinician Depression score : MADRS> 20 Introduction or switch of an antidepressant (without combination of molecules) Signed informed consent Able to understand the nature, purpose and methodology of the study French language Able to understand and conduct clinical assessments  The following psychiatric comorbidities: Bipolar disorder, schizophrenia, alcohol dependence and / or any other substance objectivized during the clinical evaluation Patient presenting a depressive episode characterized with mixed component, psychotic, melancholic or catatonic characteristics Score MADRS greater than or equal to 5 to one of the items Subject protected by law (guardianship or curatorship) Subject in period from another protocol Subject not affiliated to, or not beneficiary of, a social security scheme Pregnant orbreastfeeding patient
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-50.0,  Persistent Post-Concussive Syndrome Man or woman aged 18-50 years. 2. Reports at least one PCS symptom that is mild in severity. 3. It has been two weeks since date of injury  Has been previously diagnosed with a psychological/neurological disorder 2. Has been previously diagnosed with a substance abuse disorder/impairment, 3. Is currently seeking therapy/counseling 4. Does not have valid driver's license and 12 months of driving experience
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Cardiovascular Diseases Depression Ability to give informed consent Fluent in English Between the ages of 18-65 Lives in the United States Self-report of having experienced depression as assessed by the Mini International Neuropsychiatric Interview (MINI) Self report an elevated risk for or of having cardiovascular disease ( >150 minutes of physical activity a week and BMI >25) Registered a personal account with Fitbit prior to enrollment in the study  Unwilling/unable to comply with study procedures Pregnant A total score of a 20 on the PHQ-9 (indicative of "very severe" depression) and/or a total score of a 16 on the ASRM (or indicative of "very severe" mania) Responds to item 9 (Suicidal ideation) on the PHQ-9 with a 2 or higher (i.e., "Thoughts that you would be better off dead or of hurting yourself in some way on more than half the days") Contraindications to exercise or diet interventions as assessed by the DASI Already owns a fitbit device or other activity monitor Suffers from repeated episodes of "blacking out" or "fainting" Survived a cardiac arrest or sudden death Has recurrent chest discomfort with activity that goes away within 10 minutes of rest or with nitroglycerin Has heart failure
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-100.0,  Primary Family Caregivers of ICU Patients Ages 18 years and over Family members (spouse, parents, or children) of patients who stay in the ICU for more than 3 days Provision of the majority of unpaid physical, emotional, and/or instrumental care to the patients Voluntarily agreement with participation in the study  A history of cognitive impairment (e.g., dementia), psychiatric disorders or neurological disorders Indication of discernible hearing deficits Difficulties in verbal communication If the caregiver's relationship to a patient is close friend or relatives (not immediate family of patients) Refusal to participate in the study
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-40.0,  Obesity Exercise Reinforcement Participants must be overweight to obese (BMI 25-35 kg/m2) Not pregnant or lactating or planning to become pregnant in the next 6 months No limitations to safely participating in physical activity  Currently dieting to lose weight and no weight loss or gain >2kg over the past 3 months Taking any medications that affect energy expenditure or eating Regularly exercising (planned and structured aerobic or resistance activity) Participants must have no major health problems, cannot have known cardiovascular (cardiac, peripheral vascular, cerebrovascular), pulmonary (COPD, interstitial lung disease, cystic fibrosis) or metabolic (diabetes, thyroid disorders, renal or liver disease) disease Tobacco use Have a medical condition that prevents safe exercise
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 20.0-55.0,  Postpartum Depression Postnatal Complication Nurse's Role Giving birth full term 39 weeks 0 days and 40 weeks 6 days (ACOG 2013) Having a phone with Android feature and having an internet connection Baby's normal birth weight and having APGAR score 8 and above  Adolescent pregnants Having anxiety and depression Complication developments in the mother or newborn after delivery Newborn stay in the intensive care unit Visually impaired, hearing impaired
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-70.0,  Colon Cancer Pathologically confirmed colon adenocarcinoma (> 15 cm from the anal verge) Radiologic T3/T4 and high risk features by CT scan No metastasis on CT or PET(positron emission computed tomography) Age ≥ 18 and ≤ 70 years ECOG (Eastern Cooperative Oncology Group) performance status 0-1 No history of colorectal cancer within 5 years No history of chemotherapy Patients with childbearing potential should use effective contraception during the study and the following 6 months Adequate bone marrow function : white blood cell count of 2 x 109/L or more with neutrophils of1.5 x 109/L or more, platelet count of 100 x 109/L or more, hemoglobin of 9 g/dL (5,6 mmol/l) or more Adequate hepatobiliary function : total bilirubin of 0.4 mg/dl or less, ASAT (aspartate aminotransferase) and ALAT (alanine aminotransferase) of 2.5 x ULN (upper limits of normal) or less, Alkaline phosphatase of 1.5 x ULN or less  Age > 70 years and < 18 years Rectal cancer : 15 cm or less from the anal verge Complicated colon cancer (complete obstruction, perforation, bleeding) Metastatic colon cancer Known hypersensitivity reaction to any of the components of study treatments Inflammatory bowel disease Hereditary nonpolyposis colorectal cancerHNPCC, familial Adenomatous Polyposis Clinically relevant coronary artery disease or history of myocardial infarction in the last 6 months, high risk of uncontrolled arrhythmia Galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption Pregnancy or breast-feeding period
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-60.0,  Major Depressive Disorder MDD Patients in whom switching to desvenlafaxine is considered by treating psychiatrist as the next treatment option. 2. MDD diagnostic confirmation with the mini-international neuropsychiatric interview (MINI) (Sheehan et al., 1998), 3. Age range between 18 and 60 4. Non-response or incomplete response to a treatment with an SSRI in the current episode. 5. Score of 18 points or higher in the Hamilton depression rating scale (HAM-D-17) (Hamilton, 1967)  Subjects will be excluded if they met or had past history for the following disorders: posttraumatic stress disorder, obsessive-compulsive disorder, schizophrenia, psychotic, delusional, bipolar or substance abuse disorders. MINI will be used to these potentially comorbid disorders. 2. Subjects with any present or past disease involving the nervous central system 3. A clinically significant unstable illness or clinically significant abnormal vital signs as determined by the investigator 4. Women entering the study could not be pregnant, and had to be oral contraceptive-free
Patient description: A 46-year-old Asian woman with MDD complains of persistent feelings of sadness and loss of interest in daily activities. She states that her mood is still depressed most of the days. She complains of loss of energy and feelings of worthlessness nearly every day. She is on anti-depressants for the past 6 months, but the symptoms are still present. She does not drink alcohol or smoke. She used to exercise every day for at least 30 min., but she doesn't have enough energy to do so for the past 3 weeks. She also has some digestive issues recently. She is married and has 4 children. She is menopausal. Her husband was diagnosed with colon cancer a year ago and is undergoing chemotherapy. Her past medical history is unremarkable. Her family history is negative for any psychologic problems. Her HAM-D score is 20.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Colon Cancer Liver Tumors Patients must be undergoing one of the following procedures as part of their routine care in order to meet the Operation for presumed stage I-IV colon cancer including colectomy, hepatectomy, or abdominal surgery (e.g. insertion of HAIP) Colectomy for presumed benign or pre-malignant colon tumors (e.g. large nonneoplastic polyps or adenomas) Open, laparoscopic, or robotic resections ≥18 years old  Extrahepatic CRC metastasis No preoperative portal venous phase CT scan performed up to two months prior to day of surgery Pathology demonstrating a malignant tumor other than colorectal adenocarcinoma Stage IV colon cancer with resectable hepatic disease undergoing hepatectomy with active primary colon tumor still in place (despite chemo-radiation therapy) and no plans for colectomy Receipt of experimental therapies for colon cancer (e.g. checkpoint inhibitors or novel targeted agents). Of note, approved targeted agents (such as anti-angiogenic agents, EGFR inhibitors etc) are not an criterion History of non-colonic malignancy w/in 5 years (except non-melanomatous skin cancer) Colon cancer with microsatellite instability (MSI-high) if known preoperatively Known hereditary colon cancer syndrome such as familial adenomatous polyposis (FAP) or hereditary nonpolyposis colorectal cancer (HNPCC) Known liver disease (e.g. non-alcoholic steatohepatitis, cirrhosis, viral or other form of hepatitis, etc) INR >2 or known clotting factor deficiency Anticipated need for full anticoagulation during hospitalization