semaj83/ctmatch_classification huggingface dataset:
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Depression Anxiety Stress Participants must be at least 18 years of age. Participants must have self-reported mild to severe symptoms of depression (5-27+) according to PHQ-9, self-reported mild to severe symptoms of anxiety (5-21+) according to GAD-7, or self-reported mild to severe symptoms of stress (15-34+) according to the stress sub-scale of DASS-21  Students who currently are in face-to-face therapy at UCCS or BHS will be excluded. Students who score in the "red zone" in terms of risk of self-harm on the screening questions routinely used at UCCS will not be referred to the study. Students who score greater than 0 on the PHQ-9 self-harm item during the initial screening phase will be automatically directed to be further evaluated and alerted that a counselor will try to reach them. Based on this further evaluation, they may be recommended to seek help from their health/counseling service and may/may not be eligible to participate in the study. They will be telephoned within 1 working day and contacted by email if they cannot be reached by phone
Patient description: A 20 yo female college student with no significant past medical history presents with a chief complaint of fatigue. She reports increased sleep and appetite over the past few months as well as difficulty concentrating on her schoolwork. She no longer enjoys spending time with her friends and feels guilty for not spending more time with her family. Her physical exam and laboratory tests, including hemoglobin, hematocrit and thyroid stimulating hormone, are within normal limits.

Clinical trial eligibility criteria: eligible ages (years): 20.0-65.0,  Major Depression unipolar major depressive disorder  neurological diseases or relevant psychiatric diseases other than major depressive disorder current medication other than SSRI or Mirtazapine manic episodes (lifetime) psychotic symptoms (lifetime) treatment with psychotherapy within the past 2 years treatment with electroconvulsive therapy (lifetime)
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Lung Diseases Sleep Apnea Syndromes
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 1.0-18.0,  Obstructive Sleep Apnea Syndrome Cleft Lip/Palate children with cleft lip/palate and signs and symptoms of OSAS, parents who can read and write English  Parents who cannot read and write English, children with severe neurological compromise
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 5.0-10.0,  Attention Disorder With Hyperactivity (ADHD) We will compare a group of children with ADHD, other psychiatric disorder, and a healthy group of children age 5  mental retardation -
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 3.0-12.0,  Sleep Sleep Apnea Syndromes Sleep Disordered Breathing Assent of child (if over the age of 9 or younger but able to understand the nature of the study) At least one parent or guardian must sign an informed consent Child must be either a healthy volunteer or scheduled for an adenotonsillectomy for any reason Children scheduled for adenotonsillectomies must be referred to the program by a treating otolaryngologist who practices at the University of Michigan or St. Joseph Mercy Hospital in Ann Arbor, Michigan  Mental or physical limitations that would prevent proper interpretation of neurobehavioral tests Medical history that could confound interpretation of EEG or behavioral data, including epilepsy, psychiatric diagnoses (other than disruptive behavior disorders), head trauma with loss of consciousness for more than 30 seconds, or chronic medication use (e.g., benzodiazepines, other hypnotics, or antihistamines) Current treatment by a physician or past surgical treatment for SDB A known medical condition that carries independent high risk of SDB (e.g., Pierre Robin syndrome, Down syndrome, or neuromuscular disorders) or excessive daytime sleepiness (e.g., narcolepsy) Inability to schedule polysomnography, a Multiple Sleep Latency Test, and neurobehavioral testing before the surgical date Determination by any of the patient's physicians that sleep testing is required before surgery can be scheduled (to avoid the possibility that study enrollment itself could affect ability to complete the study) Prior enrollment of a sibling in the study Expectation that the child will no longer have convenient access to University of Michigan facilities within 6 months or expectation of further surgery within that period Additional for healthy volunteers
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 20.0-80.0,  Obstructive Sleep Apnea Age 20 to 80 yrs Apnea hypopnea index (AHI) > 10/hr on Polysomnograph (PSG) with symptoms of obstructive sleep apnea (OSA) as described previously Epworth Sleepiness Scale (ESS) >10 Patients with hypertension will still be eligible to enter and continue the study as long as there is no alteration of anti-hypertensive medications during the study period  Patients having problems staying awake during driving, shift work Recent myocardial infarction Unstable angina Underlying malignancy
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Seasonal Allergic Rhinitis Must be >=18 years of age and older, of either sex, and of any race Clinically symptomatic at Screening (Day -7 to -4)and at Baseline (Day 1) At Screening Visit, must have complaints of sleep disturbance while symptomatic with seasonal allergic rhinitis (SAR) and must have a score of 30 or greater for the Sleep Disturbance Sleep Scale (items 1,3,7 and 8) At the Baseline Visit, must have complaints of sleep disturbance and daytime somnolence while symptomatic with SAR and with a score of 30 or greater for the Sleep Problems Index II (SLP9) and 30 or greater for the Daytime Somnolence Sleep Scale (items 6, 9, and 11) Must have a 2-year or longer history of SAR occurring during the same season as the current study Must have skin tests positive for outdoor allergens common in subjects with SAR prevalent during the time of this study, such as, trees, grasses, weeds, ragweed, and molds. The skin tests should be performed at Screening if not done within 12 months prior to the Screening Visit Must be free of clinically significant disease that would interfere with study evaluations Women of childbearing potential need to use a medically accepted method of birth control prior to Screening and during the study, or provide documentation of surgical sterilization. Women who are not sexually active at enrollment must consent to the use of a medically accepted method of birth control if/when they become sexually active during study participation Female subjects of childbearing potential must have a negative urine pregnancy test at the time of enrollment at the Baseline Visit  Women who are pregnant, intend to become pregnant during the study, or are nursing Evidence of nasal polyps, deviated septum, or other intranasal anatomical obstruction(s) that would interfere with nasal airflow Acute or chronic sinusitis being treated with antibiotics and/or topical or oral nasal decongestants Acute respiratory infection within 2 weeks of the Screening Visit Diagnosis of clinically relevant sleep problems unassociated with allergies Complaints (within 12 months of the Screening Visit to their health-care provider) of difficulty sleeping or daytime sleepiness while not experiencing SAR symptoms, and continue with these complaints Snoring associated with an enlarged uvula or other upper airway pathology Had episodes of snoring associated with gasping or choking Awakened suddenly, on more than 1 occasion during the month preceding the Screening Visit, with a gasping or choking feeling Requires the use of oral appliances at night for bruxism (teeth gnashing) or temporomandibular joint problems
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Sleep Apnea, Obstructive Experiences symptoms of OSA, including snoring and sleepiness Stable medical history with no change in medications that could affect sleepiness  Suspected diagnosis of a sleep disorder other than OSA (i.e., periodic leg movements, narcolepsy, insomnia, central sleep apnea, sleep hypoventilation syndrome) Medically unstable health conditions (e.g., heart attack, congestive heart failure) Use of psychotropic medications that cause sedation in the 3 months prior to study entry Recent or confirmed history of recreational drug use or alcohol abuse Pregnant Inability to communicate verbally, write, or read Visual, hearing, or cognitive impairment
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 45.0-85.0,  Parkinson's Disease 85 years of age and living in the community Male or female of non-child bearing potentials (non-child bearing is defined as at lease 6 months post-menopause or surgically sterile) Must have a diagnosis of Parkinson's disease Must have complaints of sleep disturbance  Patients with diagnosis of or those meeting DSM-IV for major depression, schizophrenia or schizoaffective disorder, bipolar disorder, substance abuse disorder, other mental illness that is known to contribute to sleep disturbance, epilepsy, other medical conditions that are known to cause or contribute to sleep disturbances Patients currently using melatonin or ramelteon, hypnotics, benzodiazepines, antidepressants, blood-brain barrier permeable beta blockers, steroids, antipsychotics Patients with clinically significant blood or urine abnormalities Patients who have taken any investigational drug less than 1 month prior to the baseline visit Patients with multiple concomitant disorders with or without medications thought to produce sleep disturbances Patients with pre-existing sleep disturbances unrelated to Parkinson's disease Patients with severe hepatic impairment (Child-Pugh Class C) Patients with severe COPD (those with elevated pCO2 levels or those needing nocturnal oxygen therapy Patients with severe sleep apnea Patients who have sensitivity to ramelteon or any constituents of the Rozerem preparation
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 2.0-18.0,  Insomnia Sleep Disorder Male or female between the ages of 2 years and 18 years Written consent must be obtained form the parent/legal guardian for all minors. Written assent must be obtained from all minors > 6 years of age Female subjects of child-bearing potential must not be pregnant and if females are fertile and sexually active, must have documented a negative urine HCG and assure use of effective contraception acceptable to the investigator (abstinence accepted) during the study period Subjects must meet the following for a diagnosis of insomnia as determined by the subject's private physician or study investigator and subject's history the complaint is significant difficulty (defined by frequency, severity, and/or chronicity) initiating or maintaining sleep;. The problem is viewed problematic by the child and/or caregiver the sleep disturbance causes clinically significant impairment in school performance, behavior, learning, or development for the child as reported by the child and/or caregiver the sleep disturbance does not occur exclusively in the context of an intrinsic dyssomnia such as narcolepsy, restless legs syndrome, or sleep-related breathing disorders; a circadian rhythm disorder; or a parasomnia the sleep disturbance is not attributable to either the direct physiologic effect of a drug of abuse or misuse of a prescribed medication  Pregnancy and/or breastfeeding The presence of any untreated (where treatment is available), or unstable, progressive, or evolving clinically significant renal, endocrine, hepatic, respiratory, cardiovascular, neurologic, hematologic, immunologic, cerebrovascular disease or malignancy Elevations in screening blood tests of renal (SCr) and liver (ALT, AST and/or bilirubin) > 2 times the upper limit of normal for age Receiving any medications that may modulate Zolpidem metabolism, primarily drugs that will enhance or reduce the activity of CYP450 3A, 2C9, or 2D6 activity. Note: If patient is receiving a medication that might be considered an inducer or an inhibitor, please discuss with the PI prior to excluding them Receiving any medications with sleep-impairing properties at a dose/dose interval that would be judged by the study investigator as to interfere with the assessment of Zolpidem sleep response Currently using any systemic contraceptive steroids including: oral contraceptives, transdermal patch, vaginal insert, levonorgestrel implant and medroxyprogesterone acetate contraceptive injection
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 30.0-80.0,  Sleep Apnea, Obstructive Continuous Positive Airway Pressure OSA confirmed by polysomnography (PSG) CPAP is the prescribed form of treatment for OSA Judged by sleep physician to respond to CPAP  Apnea/hypoxia index (AHI) less than 15 and no daytime functional symptoms or associated cardiovascular disease Diagnosis of another sleep disorder that causes arousals from sleep Past treatment for OSA Current substance abuse problem Diagnosis of a serious medical condition that would interfere with involvement in the study History of a major psychiatric disorder, other than depression Change in antidepressant medication in the 3 months before study entry
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 4.0-9.0,  Sleep Problems Diagnosis of ASD Age greater than or equal to 4 or less than or equal to 9 years Current sleep problems, as defined as a composite score of greater than 41 on the CSHQ Failed sleep hygiene, as described below Parents must be fluent in English in order to complete CSHQ and ABC, validated in English only Parents have given informed consent  Current use of psychoactive medications (e.g. fluoxetine, methylphenidate, risperidone, lithium, etc.) Current or use within the last month of beta-blockers or melatonin Current use of sleep aids Presence of untreated medical problems that could otherwise explain sleep problems (e.g. obstructive sleep apnea, gastroesophageal reflux disease (GERD)) 5) Blindness
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Schizophrenia Key The patient has a diagnosis of schizophrenia according to the DSM-IV-TR and the patient has been clinically stable in a nonacute phase of their illness Documentation that the patient has received treatment with olanzapine, oral risperidone, or paliperidone for schizophrenia for at least 6 weeks prior to the screening visit and has been on a stable dose of that antipsychotic medication for at least 4 weeks prior to the screening visit The patient is in good health (except for the diagnosis of schizophrenia) as judged by the investigator Women of childbearing potential (not surgically sterile or 2 years postmenopausal) must use a medically accepted method of contraception and must agree to continue use of this method for the duration of the study and for 30 days after participation in the study. Acceptable methods of contraception barrier method with spermicide, intrauterine device (IUD), steroidal contraceptive (oral, transdermal, implanted, and injected) in conjunction with a barrier method, or documented abstinence The patient has a PANSS negative symptom score of 15 or more at the screening and baseline visits Key  The patient has a severity rating of moderate or worse on any item of the PANSS positive symptom subscale The patient has any Axis I disorder according to DSM-IV-TR including schizoaffective disorder, apart from schizophrenia and nicotine dependence, or any Axis II disorder that would interfere with the conduct of the study The patient has moderate to severe depressive symptoms, as indicated by the CDSS The patient has current active suicidal ideation, is at imminent risk of self-harm, or has a history of significant suicidal ideation or suicide attempt at any time in the past that causes concern at present The patient has tardive dyskinesia, akathisia, moderate or worse level of extrapyramidal symptoms, or any other clinically significant movement disorder The patient has a history of any cutaneous drug reaction or drug hypersensitivity reaction, a history of any clinically significant hypersensitivity reaction, or has a history of multiple clinically relevant allergies The patient is a pregnant or lactating woman The patient has previously received modafinil or armodafinil, or the patient has a known sensitivity to any ingredients in the study drug tablets
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 9.0-14.0,  Sleep Difficulties in Pediatric Anxiety Disorder Generalized Anxiety Disorder Separation Anxiety Disorder Social Phobia Clinical diagnosis of DSM-IV diagnosis of Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), and Social Phobia (SP) Previous enrollment Cognitive Behavioral Therapy arm in ClinicalTrials.gov Identifier: NCT00774150 study, entitled, " Transdisciplinary Studies of CBT for Anxiety in Youth: Child Anxiety Treatment Study (CATS)" The child/adolescent must have a "sleep problem" defined as: difficulties at least 3 times within a 2-week period in one or more of the following domains difficulties going to sleep difficulties waking during the night difficulties getting up on time for school because of tiredness/sleepiness daytime tiredness and/or irritability that the child or parent attributed to insufficient sleep erratic sleep-wake schedules  IQ below 70 as assessed by the Wechsler Abbreviated Scale of Intelligence (WASI) Requires current ongoing treatment with psychoactive medications including anxiolytics and antidepressants Acutely suicidal or at risk for harm to self or others Any motor impairments or eye-hand coordination problems Sleep disorder or parasomnia Taking any medication that might interfere with sleep Has a medical problem that might interfere with sleep
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 21.0-999.0,  Obstructive Sleep Apnea Consenting adults over the age of 21 Diagnosed obstructive sleep apnea  Unstable cardiovascular disease Uncontrolled hypertension (BP > 190/110) Severe intrinsic lung diseases (supplemental O2 > 2 L/min during the day) History of chronic renal insufficiency History of hepatic insufficiency Pregnancy Bleeding disorders or Coumadin use Sleep Disorders other than OSA Tracheostomy Allergy to lidocaine
Patient description: A 10 yo boy with nighttime snoring, pauses in breathing, and restlessness with nighttime awakenings. No history of headache or night terrors. The boy's teacher recently contacted his parents because she was concerned about his declining grades, lack of attention, and excessive sleepiness during class.

Clinical trial eligibility criteria: eligible ages (years): 21.0-999.0,  Obstructive Sleep Apnea years or older Patient of the Weill Cornell Pulmonary Associates and Cornell Center for Sleep Medicine practices Clinically indicated for an overnight sleep study within six months prior to or after the outpatient office visit  Pregnancy