semaj83/ctmatch_classification huggingface dataset:
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 0.083-18.0,  Diarrhea The parents and the child who give consent The children who are treated for the acute infections in the outpatient clinics and whole treatment is completed in the outpatient clinics Children who are born mature, for the children who are younger than 1 year of age  The parents and child who do not give consent Children who have primary and secondary immunosuppressive states Children who had abdominal/gastrointestinal tract surgery in the past Children who had used probiotics/prebiotics in the last one month period Children who had used antibiotics in the last one month period Children who has accompanying gastrointestinal symptoms Children who are using anti-acid treatment at the time of involvement
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 0.5-18.0,  Hemolytic-Uremic Syndrome Age <18.0 years; 2. STEC infection [positive culture OR antigen OR polymerase chain reaction test for Stx/gene]; 3. Day of illness 1-10: Children who develop HUS will do so by day #14 of illness;8 restricting enrolment to the first 10 days will ensure all participants are at risk of HUS  Evidence of evolving HUS: A) Hematocrit <30% OR B) Platelet count <150 x 109/L; 2. Responsible physician desires patient admission (therefore unable to randomize); 3. Unable to contact family within 48 hours of positive stool test; 4. Patient with history of atypical HUS; 5. Chronic disease limiting fluid volumes administered (e.g. impaired cardiac function)
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 6.0-18.0,  Obesity, Childhood Insulin Resistance Zinc Deficiency Inositol both sexes between 6 and 18 years of age obese, according to the IOTF (Cole TJ et al., 2000) pubertal stage ≥ 3 according to the Tanner stage (Tanner et al., 1961) HOMA-IR > 2,5 or insulin > 15 µU/ml Serum Zinc level in the range of normality or under the normal levels  Adverse reactions to the product or component of the product (allergies…) Genetic obesity (Prader Willi syndrome, Down syndrome), Metabolic obesity (Laurence-Biedl syndrome…), endocrinological obesity (Cushing syndrome, hypothyroidism) Chronic diseases, hepatic or gastroenterological diseases Medical treatment for chronic diseases Supplementation with inositol-like products or supplements containing Zinc and Inositol
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Nosocomial Pneumonia Ventilator Associated Pneumonia Escherichia Coli Infections Escherichia Coli Pneumonia Escherichia Coli; Diarrhea, Enteroaggregative Mechanical Ventilation Complication adult, admitted to the intensive care unit under invasive mechanical ventilation presence of Escherichia coli in lower respiratory tract specimen
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 16.0-999.0,  Rotavirus Infections Environmental Enteric Dysfunction Enteric Infections Mother residing in an intervention or control compound of a previous sanitation trial (NCT02362932) for at least 6 months prior to recruitment and not intending to switch study compound over the next 9 months 2. Mother being pregnant and having gestational age between 3 and 9 months or being puerperal (up to 40 days postpartum) 3. Mother planning to use the prenatal care, delivery and vaccination services provided by the Ministry of Health of Mozambique 4. Mother able to understand and complete the informed consent process and allow your newborn to participate in the study 5. Mother at least 16 years of age 6. Infant eligible to receive rotavirus vaccination  Infant whose medical team considers that they cannot be part of the study 2. Infant with complications associated with gestation, childbirth or postpartum, including congenital malformations 3. Infant with any medical, psychiatric or social condition, occupational reason, or other responsibility on the part of the pregnant woman, which, in the opinion of the investigator, is a contraindication to protocol compliance or impedes the participant's ability to give informed consent 4. Infant who has already received the rotavirus vaccine
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Anemia pregnant women with hemoglobin between 8.0 and 9.9 g/dl and serum ferritin <15 μg/l  vitamin B12 deficiency anemia folic acid deficiency anemia hemoglobinopathy multiples liver disease kidney disease
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 0.083-18.0,  Ascites age from 1month to 18 year infants and children with ascites (hepatic, cardiac, renal, malignant or tuberculous ) infants and children with peritonitis  age <1month surgical conditions as ruptured viscous or located abscess
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 0.25-5.0,  Diarrhea Clinical of acute gastroenteritis: change in the consistency of stools to "loose" or liquid according to Bristol scale (6 or 7) or Amsterdam (infants) (A) and / or increase in the number of stools (greater or equal to 3 / day) with a duration of less than 72 h Age over 3 months and under 5 years Written informed consent according to ICH / GCP and local legislation, obtained before any study procedure of parents or guardians  Treatment with antibiotics, xyloglucan, gelatin tannate, racecadotril, smectite, probiotics or zinc (including oral rehydration solution containing zinc and / or probiotics) in the previous week Exclusive breastfeeding Chronic gastrointestinal disease (celiac disease, cystic fibrosis, inflammatory bowel disease, food allergy) Immunodeficiencies Malnutrition (weight / height / length less than P3 according to WHO standards) Severe dehydration Impossibility of follow-up Known hypersensitivity to gelatin or xyloglucan Absence of informed consent Caregivers / parents who can not understand or comply with all the instructions and requirements of the study
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 0.5-18.0,  Diarrhea Bloody Be aged 6 months 99 years of age 2. Have ≥3 episodes of diarrhea within the preceding 24 hours and have blood identified in the stool (by physician, nurse or parent)  Previously enrolled in the study 2. Unavailable for Day 14 follow-up 3. Currently (most recent complete blood count) known to be neutropenic (Neutrophils <1000), or at high-risk of being neutropenic (receiving chemotherapy) at present 4. Blood work performed prior to enrollment 5. Known to be STEC positive (stool culture, PCT, or toxin) 6. Pre-existing diagnosis of IBD (Crohn's disease, Ulcerative Colitis) 7. Language barrier that prevents the ability to obtain informed consent and assent (when appropriate)
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Diarrhea We will samples from participants with self-reported or clinical provider documented diarrhea defined as one or more loose or watery stools per day as defined by a or b below Cases of acute diarrhea (i.e., diarrhea which is currently active or was experienced up to one day prior to sampling or still active during sampling) will be included Cases of persistent diarrhea (i.e., diarrhea which is chronic or chronic-intermittently, i.e., once a week or more, experienced for at least 2 to 4 weeks prior to sampling), will be included. In the case of chronic diarrhea, diarrhea does not have to be active on the day of, or immediately prior to (i.e., one day) sampling. 2. Current enrollment in an active NIH protocol or enrollment in 12-NR-0195. 3. Able to provide 50ml stool sample within 2-3 hours. 4. Children will only be enrolled if they are currently enrolled in an active NIH protocol or enrolled in 12-NR-0195  This protocol will outpatients who are clinically unstable patients. Clinically unstable patient is defined as someone requiring emergent care or hospitalization. 2. Antibiotic use, which can affect intestinal flora, is not exclusionary but will be controlled for via post-hoc analysis. 3. NINR employees, subordinates/relatives/ or co-workers. 4. Any NIH employee who is a subordinates/relatives/or co-workers of study investigator
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 11.0-17.0,  Clavicle Fracture Adolescent 17 years old with fractures of the middle third of the clavicle Displaced 100% the width of the clavicle or shortened 1 centimeter Operative and non-operative treated clavicles will be eligible for enrollment  Open clavicle fractures Ipsilateral shoulder injuries Fractures involving the lateral ligaments or the sternoclavicular joint Bilateral clavicle fractures Pathologic fractures Refractures Fractures with neurovascular compromise Displaced fractures with impending skin compromise If there has been more than 21 days between injury and enrollment Patients with cognitive disabilities that inhibit the completion of the questionnaires
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 5.0-999.0,  Influenza, Human With 48 hours or less of an influenza illness documented by polymerase chain reaction Have AT LEAST 2 of the following 7 influenza symptoms (nasal congestion, sore throat, cough, aches and pains, fatigue, headaches, and chills or sweats) graded as either moderate or severe Have access to a phone Subjects are capable of giving informed consent or have an acceptable legally authorized representative capable of giving consent on the subject's behalf with informed assent given by subject Have been prescribed or offered a prescription for oseltamivir (Tamiflu)  Known allergy to elderberry extract or oseltamivir Use of antibiotic or antiviral medication on presentation to the study Women who are pregnant, breastfeeding women, or do not agree to appropriate contraception (abstinence, hormonal, intrauterine device, and barrier) to prevent pregnancy during the study Patients with HIV Patients with cystic fibrosis Patients taking elderberry extract
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 40.0-75.0,  COPD Provide informed consent Male or female aged 40 to 75 years Meeting specified contraception requirements lead electrocardiogram with heart rate 50-90 beats per minute, QT interval corrected using Fridericia's formula (QTcF) ≤450 msec (males) or ≤470 msec (females), QRS interval ≤120 msec, PR interval ≤200 msec and no clinically significant abnormalities Capable of complying with all study restrictions and procedures, including ability to use the study nebulizer correctly Body mass index (BMI) 18 to 35 kg/m2 and minimum weight 45 kg COPD diagnosis with symptoms compatible with COPD for at least 1 year Clinically stable COPD in the previous 4 weeks Ability to perform acceptable and reproducible spirometry Post-bronchodilator spirometry at screening must demonstrate FEV1/forced vital capacity (FVC) ratio of ≤0.70 and FEV1 must be ≥40 % to ≤80% of predicted normal  A history of life-threatening COPD including Intensive Care Unit admission and requiring intubation COPD exacerbation requiring oral steroids in the previous 3 months A history of one or more hospitalizations for COPD in the previous 6 months Lower respiratory tract infection treated with antibiotics in the previous 3 months Evidence of cor pulmonale or clinically significant pulmonary hypertension Patients with a current diagnosis of asthma, active tuberculosis, lung cancer, bronchiectasis, sarcoidosis, lung fibrosis, interstitial lung diseases, sleep apnea, known alpha-1 antitrypsin deficiency or other active pulmonary diseases Previous lung resection or lung reduction surgery Oral therapies for COPD (e.g. oral steroids, theophylline, and roflumilast) in the previous 3 months and throughout the study Pulmonary rehabilitation, unless such treatment has been stable from 4 weeks prior to Visit 1) and remains stable during the trial A history of, or reason to believe a subject has, drug or alcohol abuse in the previous 3 years
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 15.0-60.0,  Inflammatory Bowel Diseases patients diagnosed ulcerative colitis at age(15-60) patients diagnosed crohns disease at age(15-60)k  liver cirrhosis and portal hypertension spontaneous bacterial peritonitis Ischemic colitis
Patient description: A 17 year old boy complains of vomiting, non-bloody diarrhea, abdominal pain, fever, chills and loss of appetite for the past 3 days. He ate a salad at a restaurant prior to his diarrhea onset. Physical exam was remarkable for pallor, jaundice, and diffuse abdominal tenderness. Lab results were as follows: Hemoglobin: 9.7 g/dL Platelet: 110,000 /cu.mm Creatinine: 3.6 mg/dL blood urea nitrogen (BUN): 73 mg/dL direct bilirubin: 2.4 mg/dL lactate dehydrogenase (LDH): 881 IU/L (normal: 110-265 IU/L) Peripheral blood smear showed a moderate number of schistocytes and helmet cells. Shiga-like toxin-producing E. coli (STEC) stx1/stx2 were found in stools. He has no other underlying disease and he is not on any medications.

Clinical trial eligibility criteria: eligible ages (years): 17.0-65.0,  Schizophrenia Metabolic Syndrome Meet the Diagnostic and Statistical Manual (DSM-V) diagnostic for schizophrenia; 2. Duration of illness less than 3 years with current symptoms exacerbation; 3. Male and female with aged 17 to 65 years; 4. Signed the study consent for participation  Having history of substance dependence or abuse or whose symptoms are caused by the other diagnosable mental disorders; 2. Having history of traumatic brain injury, seizures or other known neurological or organic diseases of the central nervous system; 3. Taking antidepressants, stimulants, mood stabilizer or accepts electricity shock treatment; 4. Having current suicidal or homicidal thoughts or any safety concern by research staff that cannot be manage in an inpatient setting; 5. The routine blood tests showing abnormal renal, liver function; 6. Pregnant or lactating women. 7. No administration of any antibiotics in a mouth