semaj83/ctmatch_classification huggingface dataset:
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 7.0-15.0,  Perennial Allergic Rhinitis Patients aged between 7 and 15 years Patients with a weight of at least 20 kg Patients who have received a diagnosis of perennial allergic rhinitis according to the diagnostic Patients with a mean rhinorrhea score of at least 2 and a mean total score for the three major nasal symptoms [sneezing, rhinorrhea, and nasal congestion] of at least 4 on the basis of symptoms recorded in the nasal allergy diary during the observation period  Patients with vasomotor rhinitis or eosinophilic rhinitis Patients who have concurrent nasal disease that may affect the efficacy of TAU-284 Patients with a history of any of the nasal surgical procedures Patients who have a positive result for pollen antigens which are dispersed during the study period Patients who have a positive result for dog dander or cat dander antigen Patients with current or previous history of drug allergy Patients who concurrently have renal function abnormalities that may cause safety problems
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 0.0-18.0,  Head Trauma Children who had a radiography for head trauma
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 50.0-999.0,  Seizures Pneumococcal Meningitis Adult patients > or = 50 years old Diagnosed of pneumococcal meningitis due to clinical characteristics plus a positive CSF Gram stain and/or a detection of pneumococcal antigen or PCR Suspected pneumococcal meningitis since it is an episode related to otitis, pneumonia, sinusitis or pericranial fistula or in patients with known risk factors such as myeloma or splenectomy  To have seizures prior to arrive to the hospital or the in the study Pregnancy or breastfeeding To have conduction abnormalities in ECG History of allergy or intolerance to phenytoin Patients with meningitis as a complication of neurosurgical procedures Epileptic patients taking usually anticonvulsivants Refusal by the patient or family to participate and/or to sign the informed consent
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Post-lumbar Puncture Headache Backache All adult patients (>= 18 years old) referred at the Neurological Day Center to get a lumbar puncture  Contraindication to get a lumbar puncture
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-50.0,  Meningococcal Meningitis Meningococcal Infections Willing and able to give informed consent and comply with all aspects of the evaluation after the nature of the study is explain For the purpose of this study, a healthy volunteer is defined as healthy male or female, with no significant chronic conditions Age 18 to 50 years old Either gender. Abstinence or use of contraception during the eight weeks after vaccination will be required for non menopausal (< two years post-menopause) or non surgically sterile women Persons with antibody titer(s) of <2 µg/mL to serogroup(s) A, C, Y, or W-135 polysaccharides as measured by ELISA  Age less than 18 years or over 50 years History of Guillain-Barré syndrome (GBS) Pregnancy or lactation History of meningococcal meningitis History of invasive (clinical or laboratory diagnosis) meningococcal disease History of meningococcal meningitis vaccination Screening laboratory abnormalities (in the opinion of the Investigator) that would raise safety concerns for participation in the study Use of immunosuppressive drugs within 30 days prior to study enrollment, not including topical or inhaled steroids/cytotoxic agents History of anaphylactic shock, asthma, urticaria, or other allergic or hypersensitivity reactions following vaccination History of severe allergic disorders or autoimmune connective tissue disorders, including rheumatoid arthritis. A high sensitivity C-Reactive Protein (CRP) test at screening will be used as part of the assessment of autoimmune disorders by the Principal Investigator
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-50.0,  Post Dural Puncture Headache 50 years old Undergoing diagnostic LP for any indication for the first time  COPD Any known chronic pulmonary disease Acute febrile illness Persistent headaches Known sensitivity to Benzodiazepines Current or prior substance abuse disorder Cognitive decline
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-30.0,  Schistosomiasis Bilharziasis Urinary Schistosomiasis All subjects had to meet the study within 21 days prior to treatment Caucasian volunteers No smoker biological parameters (haematological, biochemical, renal and hepatic) in normal range Health Insurance sign inform consent  inflammatory or immunological pathology such as atopic diseases, evidence of inflammation or acute infection (including positive serology to viral hepatitis B and C or HIV) any immunological deficiency any clinically relevant alcohol or drug use (cannabis, opiates, cocaine, amphetamines, benzodiazepines, nicotine, barbiturates, meprobamate or antidepressant drugs according to urine drug and metabolites screen) current immunosuppressor treatment any other medication use within 2 weeks before the study any vaccination within the last 6 months no antibodies against Sh28GST protein
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 0.25-16.0,  Meningitis Age > 3 months and < 16 years Bacterial meningitis Written parental (or appropriate legal representative) informed consent prior to study  Gram-negative bacteria in the CSF Creatinine clearance < 80ml/min/1.73m2 Creatinine phosphokinase level > 2x upper age related norm Known allergy or hypersensitivity to daptomycin Known clinical significant cardiovascular, pulmonary, renal, hepatic, gastrointestinal, endocrine, hematologic, autoimmune disease, or primary immunodeficiency Height and weight below 3rd or above 95th percentile History of, or current muscular disease Underlying neurological disease with disruption of blood brain barrier Epilepsy Muscular weakness, history of peripheral neuropathy, or Guillain-Barré syndrome
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 0.167-15.0,  Bacterial Meningitis The study entry is assessed for all children at age 2 months years who present at these centers with the symptoms and signs suggestive of BM, and to whom lumbar puncture is performed All patients whose cerebrospinal fluid (CSF) turns out to be cloudy, positive by Gram staining or latex agglutination, or shows at least 50 leukocytes per mm3, will be enrolled in the study Participants  Trauma, or relevant underlying illness such as intracranial shunt, previous neurological abnormality (cerebral palsy, Down's syndrome, meningitis) Previous hearing impairment (if known) Immunosuppression, except HIV infection More than one parenteral dose of a pretreatment antimicrobial. Children with oral antimicrobials are included, this information being marked in the sheet Active tuberculosis (if tuberculotic meningitis is diagnosed during trial, it will be included in intention-to-treat (ITT) analysis) Known hepatic disease
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 0.0-0.247,  Meningitis Informed consent form signed by the parents/carers Chronological age below 90 days inclusive The presence of clinical signs consistent with BM (hyperthermia or hypothermia or temperature instability PLUS 1 or more neurological findings among coma, seizures, neck stiffness, apnoea, bulging fontanelle) OR CSF pleocytosis (≥ 20 cells/mm3) OR a positive Gram stain of CSF  Presence of a CSF device Proven viral or fungal meningitis Severe congenital malformations if the infant is not to expect to survive for more than 3 months Other situations where the treating physician considers a different empiric antibiotic regimen necessary Known intolerance or contraindication to the study medication Participation in any other clinical study of an investigational medicinal product Renal failure and requirement of haemofiltration or peritoneal dialysis Meningitis with an organism known to be resistant to meropenem
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Acute Migraine Willing and able to provide written informed consent prior to participation in the clinical investigation Male or female aged between 18 and 65 years Diagnosed as suffering from migraine with or without aura according to IHS classification (ICHD-II) Reported history of 2 to 6 migraine episodes per month during previous 3 months, confirmed during a prospective baseline period of one month Reported history of no less than 50% of migraine episodes involving moderate or severe pain intensity, confirmed during a prospective baseline period of one month Reported history of at least 48 hours of freedom from headache between migraine attacks, confirmed during a prospective baseline period of one month Reported history of the majority of untreated migraine attack durations lasting 8 hours or more Onset of migraine headache occured before age 50 Reported history of migraine for more than one year Able and willing to maintain current preventive headache medication regimen(s) (no change in type, frequency or dose) from baseline screening visit to 2 weeks post-treatment  Reported history of 15 or more headache days per month (i.e. headaches of any kind), confirmed during a prospective baseline period of one month Reported frequency of non-migraine headaches exceeding 6 days per month, confirmed during a prospective baseline period of one month Unable to distinguish between migraine headaches and other headache types at the onset of a migraine attack Treatment with Botox received within 6 months of the screening visit, or between the screening and treatment visit Previously treated with an implantable stimulator or any implantable devices in the head and/or neck Diagnosed as having a pronounced anterior septal deviation History of sinus surgery, transphenoidal surgery for pituitary or other lesions or CSF rhinorrhea Fitted with a pacemaker /defibrillator Previously treated with radiation to the face Ongoing bacterial infection in the nasal cavity
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Streptococcus Pneumoniae Neisseria Meningitidis Haemophilus Influenzae Subjects who the investigator believes can and will comply with the requirements of the protocol or subjects who the investigator believes that parent(s)/Legally Acceptable Representative(s) [LAR(s)] can and will comply with the requirements of the protocol Written informed consent obtained from the subject/from the parent(s)/LAR of the subject A male or female subject who visits the hospital with suspected bacterial meningitis CSF sample taken as part of routine practice  Child in care
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Meningitis, Bacterial Positive CSF culture and/or positive soluble antigens in CSF with or without a cell reaction Positive PCR in CSF Purpura fulminant (with or without positive CSF culture) Positive PCR in blood and/or positive blood culture AND CSF cell reaction  Age less than 18 years old Refusal to participate
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 0.0-999.0,  Pneumonia, Bacterial Pneumonia, Viral Meningitis, Bacterial Pneumonia surveillance resident of Tône sanitary district requiring hospitalisation for at least one night for clinical pneumonia syndrome hospitalised in a study site during the study period  absence of informed consent by patient or legal tutor Meningitis surveillance resident of Tône sanitary district presenting clinical signs of acute bacterial meningitis hospitalised in a study site during the study period absence of informed consent by patient or legal tutor
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Stress Disorders, Post-Traumatic Myocardial Infarction Age over 18 years STEMI (ST-elevated myocardial infarction) or non-STEMI Stable circulatory condition Numeric Rating Scale (NRS) (0-10): a score of at least 5 for "pain (during MI)" plus a score of at least 5 for "fear of dying (until admission to the CCU)" and/or "making sorrows and feeling helpless (when being told about having MI)" Written informed consent  Participating in any other randomized-controlled trial run by the Cardiology Department of the University Hospital of Bern Emergency coronary artery bypass graft surgery Comorbid serious disease likely to cause death within 1 year Current clinically severe depression Not fully oriented to the situation, person, and place Cognitive impairment according to an adapted short version of the Mini-Mental State Examination Insufficient knowledge of German language in reading and understanding Affirmation of suicidal ideation in the last two weeks
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 30.0-70.0,  Posttraumatic Stress Disorder PTSD as determined by the Structural Clinical Interview for DSMIV (SCID) interview of PTSD and the Clinical Administered PTSD Scale (CAPS) Veteran with history of active duty service and currently discharged from active duty service Free of psychotropic medication for four weeks before the study  History of shrapnel or other foreign bodies which would preclude MRI scanning Meningitis Traumatic brain injury Neurological disorder or organic mental disorder History of loss of consciousness Current or lifetime history of alcohol abuse or substance abuse or dependence base on the SCID Current or lifetime history of schizophrenia, schizoaffective disorder, or bulimia based on the SCID History of serious medical or neurological illness, such as cardiovascular, gastrointestinal, hepatic, renal, neurologic or other systemic illness Evidence of a major or neurological illness on physical examination or as a result of laboratory studies positive urine toxicology screen
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 18.0-65.0,  Tuberculous Meningitis Age 18 years or older Probable/possible tuberculosis meningitis using uniform case definition Agree to participate in the study  Patient with antituberculosis treatment within last 2 weeks Increase liver function >5x upper limit of normal Pregnancy
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 8.0-17.0,  Traumatic Brain Injury Brain Concussion Children aged between 8 and 17 years old. This will be limited to this small spectrum of age to insure better homogeneity in the evaluation of the participants and streamlining of outcome measures. Also, this is the age group for which our measurement tool has been validated Occurrence of a mTBI as defined by the presence of a head trauma, a Glasgow coma scale of 13 to 15 and at least one of the three following criteria4  Any period of loss of consciousness Any loss of memory for events immediately before or after the accident Any alteration in mental state at the time of the accident (eg, feeling dazed, disoriented) And the absence of the following Post-traumatic amnesia greater than 24 hours Glasgow Coma Scale < 13, 30 minutes post accident The trauma occurred in the preceding 24 hours  Inability to obtain a proper written informed consent (language barrier, absence of a parental authority, developmental delay, intoxication, patient too confuse to consent according to the treating physician) Known allergic reaction or intolerance to ondansetron. 3. Known rhythm or cardiac problem, or history of sudden death in the proximal family 4. Patients who are taking a medication which could increase the QT interval. 5. Patients who received ondansetron in the previous 24 hours 6. Any abnormality on radiological studies, including any bleeding in the brain or skull fracture Multi-system injuries with treatment requiring admission to hospital or procedural sedation in the ED
Patient description: A 44-year-old man was recently in an automobile accident where he sustained a skull fracture. In the emergency room, he noted clear fluid dripping from his nose. The following day he started complaining of severe headache and fever. Nuchal rigidity was found on physical examination.

Clinical trial eligibility criteria: eligible ages (years): 7.0-15.0,  Perennial Allergic Rhinitis Patients aged between 7 and 15 years Patients who have received a diagnosis of perennial allergic rhinitis according to the diagnostic Patients with a mean rhinorrhea score and a mean sneezing score of at least 2 on the basis of symptoms recorded in the nasal allergy diary during the observation period etc  Patients with vasomotor rhinitis or eosinophilic rhinitis Patients who have concurrent nasal disease that may affect the efficacy of TAU-284 Patients with a history of any of the nasal surgical procedures Patients who have a positive result for pollen antigens which are dispersed during the study period Patients who have a positive result for dog dander or cat dander antigen and have a chance to touch dogs or cats Patients with current or previous history of drug allergy Patients who concurrently have renal function abnormalities that may cause safety problems etc