semaj83/ctmatch_classification huggingface dataset:
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  High Blood Pressure Cardiovascular Complication Subject has solid cancer Subject is expected to start chemotherapy  Pregnancy and lactation Severe impaired kidney function Severe hepatic impairment Mental disease Acute myocardial infarction 28 days ago or earlier Acute Cerebrovascular Event 1 month ago or earlier Rhythm disturbance that complicate pulse wave velocity evaluation
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 55.0-999.0,  Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease) Uncontrolled Diabetes (HBA1c ≥ 10) English speaking Community-dwelling years of age Primary diagnosis of heart disease (coronary artery disease, ischemic heart disease, hypertensive heart disease), or uncontrolled diabetes (HBA1c greater than/equal to 10) Self-reported risk of functional decline (score of 3 or higher) on the 11-item Brief Risk Identification of Geriatric Health Tool or self-reported need for assistance with disease management  Current/past diagnosis of stroke or other neurological disorders Receiving pharmacological treatment for cognition Receiving outpatient rehabilitation services Participating in other exercise or ADL-focused intervention studies Non-English speaking Residing in a long-term care institution Compromised decision-making capacity (score >8 on SOMCT)
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 18.0-99.0,  Parkinson Disease Essential Tremor for PD Diagnosis of idiopathic Parkinson's disease where the diagnosis was made by a Movement Disorder Specialist according to the MDS of 2015, with a Hoehn and Yahr scale (H&Y) of at least 2 (bilateral involvement) Onset of the symptoms more than five years ago MDS-UPDRS-III score of ≥30 without medication or DBS Electrodes are implanted in target area STN. for ET Patient is diagnosed with essential tremor by a Movement Disorder Specialist Diagnosis since more than 3 years Patient has a disabling medical-refractory upper extremity tremor without medication or DBS Patient has a postural or kinetic tremor severity score of at least 3 out of 4 in the extremity intended for treatment on the Fahn-Tolosa-Marin Clinical Rating Scale for Tremor without medication or DBS Electrodes are implanted in target area VIM. General  Any significant psychiatric problems, including unrelated clinically significant depression Any current drug or alcohol abuse Any history of recurrent or unprovoked seizures Have any significant medical condition that is likely to interfere with study procedures or likely to confound evaluation of study endpoints, including any terminal illness with survival <12 months
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Parkinson Disease Eligible for DBS surgery based on multi-disciplinary consensus review Have a diagnosis of Parkinson's disease or Essential Tremor A minimum of 18 years of age Willingness to participate in the paradigms described in the protocol  Inability to provide full and informed consent Are not surgical candidates due to co-morbid conditions or pregnancy Have not undergone an adequate trial of conservative medical management Have a clinical presentation for which DBS surgery is not indicated Are not able to participate in study-related activities
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 45.0-999.0,  Alzheimer's Dementia Parkinson Disease(PD) Fronto-Temporal Dementia Hospitalized or coming to perform a consultation, for whom an Eye-Tracking examination is indicated as part of routine care Sufficient written and oral expression in French Written informed consent signed by the patient For the control group: No cognitive impairment (non pathological MMSE (according to age, gender and socio-cultural level), no neurological history, and no psychiatric history (especially anxiety and depressive disorders) For the FTD group: Patient diagnosed according to revised Rascovsky et al. 2011., no neurological history (excepted diagnosed FTD), and no psychiatric history (excepted those related to diagnosed FTD) For the AD group: Patient diagnosed according to DSM-IV-TR no neurological history (excepted diagnosed AD), and no psychiatric history (excepted those related to diagnosed AD) For the PD group: Patient diagnosed according to NINDS no neurological history (excepted diagnosed PD), and no psychiatric history (excepted those related to diagnosed PD)  General anaesthesia within 3 months Ophthalmological problems preventing a video-oculography examination Oculomotor disorders such as "fixation disorders" or "ocular tracking disorders" Cognitive disorders of the type: visual agnosia, visuo-spatial disorder, visuo-perceptual disorder or aphasia History of stroke History of alcohol or drug abuse
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 30.0-999.0,  Parkinson's Disease (PD) Completion of the parent study, Study M15-736  Participant considered by the investigator to be an unsuitable candidate to receive ABBV-951 for any reason
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Sacroiliac Instability The RSA method will be tested in patients that already have tantalum markers inserted around the SI joints from earlier studies, approximately five years ago, conducted at Ullevål University Hospital  The patients that can not perfome the provocation images of the SI joints Pregnancy Not able to or do not want to participate
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 50.0-90.0,  Parkinson Disease Healthy Adult To be eligible to participate in this study, people with PD must meet the following 1. Adult (50-90 yrs) with a positive diagnosis of Parkinson's disease from a movement disorder specialist 2. On an unchanged regimen of dopaminergic medication for at least the last 3 months 3. Able to independently walk for 6 min 4. Without other severe chronic psychiatric or medical conditions 5. Not taking any psychoactive medications To be eligible to participate in this study, the NH subjects must meet the following 1. Adult (50-90 yrs) 2. Able to independently walk for 6 min 3. Without any severe chronic psychiatric or medical conditions 4. Not taking any psychoactive medications  An individual from either group who meets any of the following will be excluded from participation in this study: 1. Pregnant 2. Known holes or fissures in the skull 3. Metallic objects or implanted devices in the skull/head (e.g., metal plate, deep brain stimulator) 4. Current or previous injuries or surgeries that cause unusual gait 5. A score less than 24 or 17 on the Montreal Cognitive Assessment (MoCA) or telephone-MoCA, respectively Additional for PwPD: 1. Experience freezing of gait 2. A diagnosis of dementia or other neurodegenerative diseases Additional for NH subjects: 1. A diagnosis of dementia or any neurodegenerative diseases
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 45.0-999.0,  Parkinson's Disease PD based on the United Kingdom Parkinson's Disease Society Brain Bank Diagnostic Research (n=64, gross recruitment) M/F age 45 years or older duration of disease > 5 years and/or Hoehn & Yahr stages 1.5-4 able to ambulate independently and no evidence of dementia  History of Meniere disease or recent onset of acute vestibular dysfunction, such as otolith disorders (BBPV etc) Other disorders which may resemble PD, such as progressive supranuclear palsy (PSP), vascular dementia, normal pressure hydrocephalus, multiple system atrophy (MSA), corticobasal ganglionic degeneration, or toxic causes of parkinsonism. Prototypical cases have distinctive clinical profiles, like early and severe dysautonomia (MSA) or appendicular apraxia, which may differentiate them from idiopathic PD and PSP. The use of the clinical diagnostic for PD will mitigate the of subjects with atypical parkinsonism Evidence of a stroke or mass lesion on structural brain imaging (MRI) Participants in whom MRI is contraindicated including, but not limited to, those with a pacemaker, presence of metallic fragments near the eyes or spinal cord, or cochlear implant Severe claustrophobia precluding MR or PET imaging Subjects limited by participation in research procedures involving ionizing radiation Pregnancy (test within 48 hours of each PET session) or breastfeeding
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Parkinson Disease Parkinson For Work Packages 1 and 2- 1. People diagnosed with Parkinson's or caregiver of someone diagnosed with Parkinson's 2. Able to consent to participate  Unable to consent to participate For Work Package 3: 1. Have a role in the care of someone with Parkinson's including but not limited to people diagnosed with Parkinson's, caregiver of someone with diagnosed with Parkinson's, healthcare professionals, volunteer sector representative, policy maker or manager 2. Able to consent to participate Unable to consent to participate
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Parkinson Disease Adult individual at least 18 years old 2. Clinical diagnosis Parkinson's Disease 3. Subject has provided informed consent before initiation of any study procedure. 4. Subject has mesenchymal stem cells banked at Hope Biosciences  Clinically significant, uncontrolled cardiovascular, lung, renal, hepatic, or endocrine disease or any other acute or chronic medical condition that, in the opinion of the investigator, may increase the risks associated with study participation. 2. Chemical or ETOH dependency that in the opinion of the investigator would preclude participation in the study 3. Participation in concurrent interventional research studies during this trial 4. Unwillingness to return for follow-up visits
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 18.0-80.0,  Emphysema or COPD COPD III-IV Age ≥ 18 years FEV1 < 50% predicted after bronchodilatation Significant hyperinflation (TLC >100% predicted, RV > 200% predicted, RV/TLC > 60%) Non-smoker or ex-smoker for > 3 months (documented by cotinine testing) MWT >150 m and ≤ 450m MRC dyspnea score > 3 Homogenous emphysema as assessed by HR-CT (< 15% difference in emphysema destruction score between target lobe and ipsilateral lobe) [16, 17] Uni or bilateral collateral ventilation (CV) negative result assessed fissure completeness>95% in QCT and confirmed by a bronchoscopic procedure (Chartis©)  Contraindication against either LVRS or BLVR and/or to surgery and bronchoscopy in general Major comorbidities limiting survival Age ≥ 80 years Nicotine abuse within 3 months (documented by cotinine testing) Predominance of either left or right lung of >70% in perfusion SPECT scintigraphy FEV1 and/or DLCO <20% predicted (post bronchodilatation) Untreated Hypoxemia (PaO2 < 50 mmHg) Untreated Hypercapnia (PaCO2 > 50 mmHg) Significant pulmonary fibrosis or bronchiectasis Destroyed/vanished lung on HR-CT
Patient description: A 57-year old farmer was diagnosed with Parkinson's disease a year ago. He experiences slowness of movement and tremors. His past medical history is significant for hypertension and hypercholesterolemia. He lives with his wife. They have three children. He used to be active with planting and taking care of their farm animals before his diagnosis. The patient complains of shaking and slow movement. He had difficulty entering through a door, as he was frozen and needed guidance to step in. His handwriting is getting smaller. He is on Levodopa and Trihexyphenidyl. He stated his medications help with shaking and slow movement. But he still has difficulty initiating movements, stiffness and slowness in general. He is an alert and cooperative man who doesn't have any signs of dementia. He doesn't smoke or use any illicit drugs.

Clinical trial eligibility criteria: eligible ages (years): 18.0-999.0,  Cirrhosis Portal Hypertension Patient with cirrhosis and portal hypertension older than 18 old Patient who underwent a CT scan or MRI in the last 3 months The Mini-Mental State (MMS) test >25 Patient capable of receiving and understanding information relating to the study and of giving his written informed consent Patient affiliated to the French social security system  Cirrhotic patient with overt HE or history of persistent or recurrent HE Hepatocellular carcinoma beyond Milan criteria Portal vein thrombosis Previous transjugular intrahepatic portosystemic shunt (TIPS) or surgical shunt Presence of neurological or psychiatric disorder Patient with treatment by benzodiazepines or opioid substitution Pregnant or nursing women Patient in period of a previous study Patient under guardianship, trusteeship or the protection of justice or incapable of giving their own informed consent