Patient description: Fernandez is a 41 year man who is a professional soccer player. He came to the clinic with itchy foot. Physical exam revealed localized scaling and maceration between the third and fourth of his right toe. It became inflamed and sore, with mild fissuring. The dorsum and sole of the foot was unaffected. There is no pus or tearing in the affected area. He didn't use ant topical ointment on the lesion and has no positive history for any underlying disease such as DM. He smokes 15 cigarettes per day and drinks a beer per day. His family history is positive for hyperlipidemia in her mother and MI in her father. He is in relation with several partners and use condom during the intercourse. His physical exam and lab studies were normal otherwise. Tinea pedis infection confirmed as his diagnosis by the observation of segmented fungal hyphae during a microscopic KOH wet mount examination.

Clinical trial eligibility criteria: eligible ages (years): 12.0-999.0,  Tinea Pedis Athlete's Foot Review and sign a statement of Informed Consent and HIPAA authorization. 2. For minors (less than 18 years), the parent/legal guardian must complete the informed consent process AND the subject must complete the assent process and sign the appropriate form (if age appropriate). 3. Males or non-pregnant females ≥12 years of age, of any race or sex. Females of childbearing potential must have a negative urine pregnancy test. 4. Presence of tinea pedis on one or both feet characterized by clinical evidence of a tinea infection (at least moderate erythema, moderate scaling, and mild pruritus)based on signs and symptoms. 5. KOH positive and culture positive baseline skin scrapings obtained from the site most severely affected or a representative site of the overall severity. 6. Subjects must be in good health and free from any clinically significant disease that might interfere with the study evaluations. 7. Subject must be able to understand the requirements of the study and willing to comply with the study requirements  A life-threatening condition (ex. autoimmune deficiency syndrome, cancer, unstable angina, or myocardial infarction) within the last 6 months. 2. Subjects with abnormal findings physical or laboratory that are considered by the investigator to be clinically important and indicative of conditions that might complicate interpretation of study results. 3. Subjects with a known hypersensitivity to study medications or their components. 4. Subjects who have a recent history or who are currently known to abuse alcohol or drugs. 5. Uncontrolled diabetes mellitus. 6. Hemodialysis or chronic ambulatory peritoneal dialysis therapy. 7. Current diagnosis of immunocompromising conditions. 8. Foot psoriasis, corns and/or callus involving any web spaces, atopic or contact dermatitis. 9. Severe dermatophytoses, onychomycosis (on the evaluated foot), mucocutaneous candidiasis, or bacterial skin infection. 10. Extremely severe tinea pedis (incapacitating). 11. Female subject who is pregnant or lactating, who is not using or does not agree to use an acceptable form of contraception during the study, or who intends to become pregnant during the study (females who are surgically sterilized or post menopausal for at least 2 years are not considered to be of childbearing potential).For the purposes of this study, acceptable forms of birth control oral contraceptives, contraceptive patches/implants, double barrier methods (e.g., use of condom and spermicide), IUD, and abstinence with second acceptable method should subject become sexually active. 12. Subjects using the following medications Topical anti-fungal therapy, foot/shoe powders, or topical corticosteroids applied to the feet within 14 days prior to randomization. Topical terbinafine, butenafine,and naftifine within 30 days prior to randomization Oral anti-fungal therapies 3 months (8 months for oral terbinafine) prior to randomization Systemic antibiotic or corticosteroid treatment within 30 days of randomization Any other significant treatments, except hormonal contraception and multivitamin, at the discretion of the investigator that would interfere with study treatment Investigational drug within 30 days of randomization