Datasets:

sarus-tech

/

phee

like 2

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"developed\"]], \"start\": [[99]], \"entity_id\": [\"T6\"]}, \"Subject\": {\"text\": [[\"a patient\"]], \"start\": [[32]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"topical 5-FU cream\"]], \"start\": [[63]], \"entity_id\": [\"T5\"], \"Route\": {\"text\": [[\"topical\"]], \"start\": [[63]], \"entity_id\": [\"T8\"]}, \"Drug\": {\"text\": [[\"5-FU\"]], \"start\": [[71]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"a severe case of angioedema\"]], \"start\": [[109]], \"entity_id\": [\"T7\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Potential_therapeutic_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Potential_therapeutic_event\", \"Trigger\": {\"text\": [[\"followed\"]], \"start\": [[64]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"Cessation of D-Pen and the start of corticosteroid therapy\"]], \"start\": [[0]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"D-Pen\"], [\"corticosteroid\"]], \"start\": [[13], [36]], \"entity_id\": [\"T3\", \"T7\"]}, \"Disorder\": {\"text\": [[\"bicytopenia\"]], \"start\": [[90]], \"entity_id\": [\"T1\"]}}, \"Effect\": {\"text\": [[\"recovery from bicytopenia\"]], \"start\": [[76]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Potential_therapeutic_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Potential_therapeutic_event\", \"Trigger\": {\"text\": [[\"Prevention\"]], \"start\": [[0]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"immunization, together with early recognition and prompt antiviral treatment\"]], \"start\": [[27]], \"entity_id\": [\"T8\"], \"Disorder\": {\"text\": [[\"infection\"]], \"start\": [[14]], \"entity_id\": [\"T7\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"after\"]], \"start\": [[48]], \"entity_id\": [\"T4\"]}, \"Effect\": {\"text\": [[\"normotensive scleroderma renal crisis\"]], \"start\": [[10]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"high-dose methylprednisolone treatment\"]], \"start\": [[54]], \"entity_id\": [\"T5\"], \"Dosage\": {\"text\": [[\"high-dose\"]], \"start\": [[54]], \"entity_id\": [\"T7\"]}, \"Drug\": {\"text\": [[\"methylprednisolone\"]], \"start\": [[64]], \"entity_id\": [\"T8\"]}}, \"Subject\": {\"text\": [[\"A case\"]], \"start\": [[0]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"has been observed\"]], \"start\": [[54]], \"entity_id\": [\"T4\"]}, \"Effect\": {\"text\": [[\"delayed stroke-like leukoencephalopathy\"]], \"start\": [[14]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"methotrexate (MTX)\"]], \"start\": [[94]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"methotrexate\"]], \"start\": [[94]], \"entity_id\": [\"T9\"]}, \"Disorder\": {\"text\": [[\"childhood leukemia\"]], \"start\": [[117]], \"entity_id\": [\"T10\"]}}, \"Subject\": {\"text\": [[\"patients\", \"childhood leukemia\"]], \"start\": [[75, 117]], \"entity_id\": [\"T8\"], \"Age\": {\"text\": [[\"childhood\"]], \"start\": [[117]], \"entity_id\": [\"T7\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[11]], \"entity_id\": [\"T10\"]}, \"Treatment\": {\"text\": [[\"Duloxetine\"]], \"start\": [[0]], \"entity_id\": [\"T9\"], \"Drug\": {\"text\": [[\"Duloxetine\"], [\"thiazide diuretics\"]], \"start\": [[0], [67]], \"entity_id\": [\"T13\", \"T15\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"with\"]], \"start\": [[62]], \"entity_id\": [\"T12\"]}, \"Drug\": {\"text\": [[\"thiazide diuretics\"], [\"Duloxetine\"]], \"start\": [[67], [0]], \"entity_id\": [\"T15\", \"T13\"]}}]}, \"Effect\": {\"text\": [[\"hyponatremia\"]], \"start\": [[19]], \"entity_id\": [\"T11\"]}, \"Subject\": {\"text\": [[\"an elderly patient treated with thiazide diuretics\"]], \"start\": [[35]], \"entity_id\": [\"T7\"], \"Age\": {\"text\": [[\"elderly\"]], \"start\": [[38]], \"entity_id\": [\"T8\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"relationship\"]], \"start\": [[135]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"olanzapine\"]], \"start\": [[151]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"olanzapine\"]], \"start\": [[151]], \"entity_id\": [\"T8\"]}}, \"Effect\": {\"text\": [[\"metabolic changes manifested as uncontrolled diabetes mellitus and weight gain\"]], \"start\": [[165]], \"entity_id\": [\"T7\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Potential_therapeutic_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Potential_therapeutic_event\", \"Trigger\": {\"text\": [[\"treat\"]], \"start\": [[74]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"Arsenic trioxide\"]], \"start\": [[0]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"Arsenic trioxide\"]], \"start\": [[0]], \"entity_id\": [\"T8\"]}, \"Disorder\": {\"text\": [[\"refractory acute promyelocytic leukemia\"]], \"start\": [[80]], \"entity_id\": [\"T9\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E2", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E2\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"developed\"]], \"start\": [[19]], \"entity_id\": [\"T7\"]}, \"Subject\": {\"text\": [[\"the child\"]], \"start\": [[63]], \"entity_id\": [\"T3\"], \"Age\": {\"text\": [[\"child\"]], \"start\": [[67]], \"entity_id\": [\"T6\"]}}, \"Effect\": {\"text\": [[\"the t-AML\"]], \"start\": [[9]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"oral etoposide therapy\", \"high-dose, multiagent chemotherapy\"]], \"start\": [[39, 97]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"etoposide\"], [\"chemotherapy\"]], \"start\": [[44], [119]], \"entity_id\": [\"T8\", \"T11\"]}, \"Route\": {\"text\": [[\"oral\"]], \"start\": [[39]], \"entity_id\": [\"T9\"]}, \"Dosage\": {\"text\": [[\"high-dose\"]], \"start\": [[97]], \"entity_id\": [\"T13\"]}, \"Combination\": [{\"event_id\": \"E1\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"received\"]], \"start\": [[88]], \"entity_id\": [\"T10\"]}, \"Drug\": {\"text\": [[\"chemotherapy\"], [\"etoposide\"]], \"start\": [[119], [44]], \"entity_id\": [\"T11\", \"T8\"]}}]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"during\"]], \"start\": [[29]], \"entity_id\": [\"T3\"]}, \"Effect\": {\"text\": [[\"Heat stroke\"]], \"start\": [[0]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"clozapine\"]], \"start\": [[36]], \"entity_id\": [\"T6\"], \"Disorder\": {\"text\": [[\"schizophrenia\"]], \"start\": [[15]], \"entity_id\": [\"T5\"]}, \"Drug\": {\"text\": [[\"clozapine\"]], \"start\": [[36]], \"entity_id\": [\"T7\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"taking\"]], \"start\": [[42]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"nitrendipine\", \"few days after\"]], \"start\": [[49, 27]], \"entity_id\": [\"T4\"], \"Time_elapsed\": {\"text\": [[\"few days afte\"]], \"start\": [[27]], \"entity_id\": [\"T7\"]}, \"Drug\": {\"text\": [[\"nitrendipine\"]], \"start\": [[49]], \"entity_id\": [\"T8\"]}}, \"Effect\": {\"text\": [[\"same symptoms\"]], \"start\": [[4]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"effect\"]], \"start\": [[74]], \"entity_id\": [\"T8\"]}, \"Subject\": {\"text\": [[\"two cases\"]], \"start\": [[19]], \"entity_id\": [\"T5\"], \"Population\": {\"text\": [[\"two\"]], \"start\": [[19]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"acute dystonic reactions (ADRs)\"]], \"start\": [[32]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"lamivudine\"]], \"start\": [[84]], \"entity_id\": [\"T7\"], \"Drug\": {\"text\": [[\"lamivudine\"]], \"start\": [[84]], \"entity_id\": [\"T10\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[10]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"Isoniazid\"]], \"start\": [[0]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"Isoniazid\"]], \"start\": [[0]], \"entity_id\": [\"T7\"]}}, \"Effect\": {\"text\": [[\"anaphylaxis\"]], \"start\": [[18]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[44]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"amiodarone\"]], \"start\": [[33]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"amiodarone\"]], \"start\": [[33]], \"entity_id\": [\"T6\"]}}, \"Effect\": {\"text\": [[\"hypothyroidism\"]], \"start\": [[52]], \"entity_id\": [\"T5\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"from\"]], \"start\": [[24]], \"entity_id\": [\"T4\"]}, \"Effect\": {\"text\": [[\"Deepening of lid sulcus\"]], \"start\": [[0]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"bimatoprost\"]], \"start\": [[37]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"bimatoprost\"]], \"start\": [[37]], \"entity_id\": [\"T6\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[26]], \"entity_id\": [\"T4\"]}, \"Effect\": {\"text\": [[\"Gastro-oesophageal reflux\"]], \"start\": [[0]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"nifedipine\"]], \"start\": [[42]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"nifedipine\"]], \"start\": [[42]], \"entity_id\": [\"T6\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"starting\"]], \"start\": [[88]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"quinapril therapy\"]], \"start\": [[97]], \"entity_id\": [\"T4\"], \"Time_elapsed\": {\"text\": [[\"within one month\"]], \"start\": [[68]], \"entity_id\": [\"T9\"]}, \"Drug\": {\"text\": [[\"quinapril\"]], \"start\": [[97]], \"entity_id\": [\"T10\"]}, \"Disorder\": {\"text\": [[\"essential hypertension\"]], \"start\": [[136]], \"entity_id\": [\"T12\"]}}, \"Subject\": {\"text\": [[\"A 68-year-old woman\"]], \"start\": [[14]], \"entity_id\": [\"T5\"], \"Age\": {\"text\": [[\"68-year-old\"]], \"start\": [[16]], \"entity_id\": [\"T7\"]}, \"Gender\": {\"text\": [[\"woman\"]], \"start\": [[28]], \"entity_id\": [\"T8\"]}}, \"Effect\": {\"text\": [[\"a dry, irritating cough\"]], \"start\": [[44]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[11]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"Sertraline\"]], \"start\": [[0]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"Sertraline\"]], \"start\": [[0]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"rhabdomyolysis\"]], \"start\": [[19]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"an elderly patient with dementia and comorbidities\"]], \"start\": [[37]], \"entity_id\": [\"T6\"], \"Age\": {\"text\": [[\"elderly\"]], \"start\": [[40]], \"entity_id\": [\"T7\"]}, \"Disorder\": {\"text\": [[\"dementia\"], [\"comorbidities\"]], \"start\": [[61], [74]], \"entity_id\": [\"T8\", \"T1\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Potential_therapeutic_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Potential_therapeutic_event\", \"Trigger\": {\"text\": [[\"disappeared\"]], \"start\": [[191]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"After the dose of methylprednisolone was reduced from 40 mg to 20 mg i.v. q6h and shifted to other anti-asthma treatment by procaterol metered dose inhaler via spacer\", \"a few hours later\"]], \"start\": [[0, 203]], \"entity_id\": [\"T5\"], \"Disorder\": {\"text\": [[\"psychotic reaction\"]], \"start\": [[172]], \"entity_id\": [\"T4\"]}, \"Time_elapsed\": {\"text\": [[\"a few hours\"]], \"start\": [[203]], \"entity_id\": [\"T6\"]}, \"Drug\": {\"text\": [[\"methylprednisolone\"]], \"start\": [[18]], \"entity_id\": [\"T7\"]}, \"Dosage\": {\"text\": [[\"reduced from 40 mg to 20 mg i.v. q6h\"]], \"start\": [[41]], \"entity_id\": [\"T8\"]}, \"Route\": {\"text\": [[\"spacer\"]], \"start\": [[160]], \"entity_id\": [\"T9\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"for\"]], \"start\": [[88]], \"entity_id\": [\"T9\"]}, \"Effect\": {\"text\": [[\"increased lipid levels\"]], \"start\": [[92]], \"entity_id\": [\"T7\"]}, \"Treatment\": {\"text\": [[\"Sirolimus works differently from the immunosuppressants currently available\"]], \"start\": [[0]], \"entity_id\": [\"T8\"], \"Drug\": {\"text\": [[\"Sirolimus\"], [\"immunosuppressants\"], [\"sirolimus\"], [\"cyclosporine\"], [\"tacrolimus\"]], \"start\": [[0], [37], [148], [231], [247]], \"entity_id\": [\"T10\", \"T11\", \"T12\", \"T13\", \"T14\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Potential_therapeutic_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Potential_therapeutic_event\", \"Trigger\": {\"text\": [[\"for\"]], \"start\": [[24]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"warfarin\"]], \"start\": [[15]], \"entity_id\": [\"T5\"], \"Disorder\": {\"text\": [[\"a prior deep venous thrombosis\"]], \"start\": [[28]], \"entity_id\": [\"T7\"]}, \"Drug\": {\"text\": [[\"warfarin\"]], \"start\": [[15]], \"entity_id\": [\"T9\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[11]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"Quetiapine\"]], \"start\": [[0]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"Quetiapine\"]], \"start\": [[0]], \"entity_id\": [\"T7\"]}}, \"Effect\": {\"text\": [[\"myoclonus\"]], \"start\": [[19]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[17]], \"entity_id\": [\"T4\"]}, \"Effect\": {\"text\": [[\"Dyspnea\"]], \"start\": [[0]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"controlled-release morphine sulfate tablets\"]], \"start\": [[33]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"morphine sulfate\"]], \"start\": [[52]], \"entity_id\": [\"T7\"]}, \"Route\": {\"text\": [[\"tablets\"]], \"start\": [[69]], \"entity_id\": [\"T8\"]}, \"Dosage\": {\"text\": [[\"controlled-release\"]], \"start\": [[33]], \"entity_id\": [\"T9\"]}}, \"Speculated\": {\"text\": [[\"possibly\"]], \"start\": [[8]], \"entity_id\": [\"T6\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"by\"]], \"start\": [[67]], \"entity_id\": [\"T7\"]}, \"Treatment\": {\"text\": [[\"melarsoprol\"]], \"start\": [[70]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"melarsoprol\"]], \"start\": [[70]], \"entity_id\": [\"T8\"]}, \"Duration\": {\"text\": [[\"August 1992 and September 1993\"]], \"start\": [[89]], \"entity_id\": [\"T9\"]}}, \"Subject\": {\"text\": [[\"patients\"]], \"start\": [[50]], \"entity_id\": [\"T5\"]}, \"Effect\": {\"text\": [[\"ARE\"]], \"start\": [[17]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"developed\"]], \"start\": [[42]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"adenine arabinoside\"]], \"start\": [[162]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"adenine arabinoside\"]], \"start\": [[162]], \"entity_id\": [\"T10\"]}, \"Disorder\": {\"text\": [[\"disseminated herpes zoster\"]], \"start\": [[15]], \"entity_id\": [\"T11\"]}}, \"Effect\": {\"text\": [[\"syndrome of inappropriate antidiuretic hormone and profound hyponatremia\"]], \"start\": [[54]], \"entity_id\": [\"T7\"]}, \"Subject\": {\"text\": [[\"A patient with disseminated herpes zoster\"]], \"start\": [[0]], \"entity_id\": [\"T8\"]}, \"Severity\": {\"text\": [[\"profound\"]], \"start\": [[105]], \"entity_id\": [\"T12\"], \"value\": \"High\"}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"after\"]], \"start\": [[76]], \"entity_id\": [\"T4\"]}, \"Subject\": {\"text\": [[\"One patient with systemic lupus erythematosus\"]], \"start\": [[0]], \"entity_id\": [\"T3\"], \"Population\": {\"text\": [[\"One\"]], \"start\": [[0]], \"entity_id\": [\"T7\"]}, \"Disorder\": {\"text\": [[\"systemic lupus erythematosus\"]], \"start\": [[17]], \"entity_id\": [\"T8\"]}}, \"Effect\": {\"text\": [[\"erythema multiforme\"]], \"start\": [[56]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"griseofulvin\"]], \"start\": [[89]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"griseofulvin\"]], \"start\": [[89]], \"entity_id\": [\"T9\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"following\"]], \"start\": [[50]], \"entity_id\": [\"T8\"]}, \"Subject\": {\"text\": [[\"a 34-yr-old man\"]], \"start\": [[149]], \"entity_id\": [\"T5\"], \"Age\": {\"text\": [[\"34-yr-old\"]], \"start\": [[151]], \"entity_id\": [\"T9\"]}, \"Gender\": {\"text\": [[\"man\"]], \"start\": [[161]], \"entity_id\": [\"T10\"]}}, \"Effect\": {\"text\": [[\"colonic mucosal necrosis\"]], \"start\": [[25]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"Kalimate (calcium polystryrene sulfonate), an analogue of Kayexalate without sorbitol\"]], \"start\": [[60]], \"entity_id\": [\"T7\"], \"Drug\": {\"text\": [[\"Kalimate\"], [\"(calcium polystryrene sulfonate)\"], [\"Kayexalate\"]], \"start\": [[60], [69], [118]], \"entity_id\": [\"T11\", \"T12\", \"T13\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[27]], \"entity_id\": [\"T4\"]}, \"Effect\": {\"text\": [[\"Bilateral anterior uveitis\"]], \"start\": [[0]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"clomiphene citrate\"]], \"start\": [[43]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"clomiphene citrate\"]], \"start\": [[43]], \"entity_id\": [\"T6\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"following\"]], \"start\": [[19]], \"entity_id\": [\"T7\"]}, \"Effect\": {\"text\": [[\"Progressive anemia\"]], \"start\": [[0]], \"entity_id\": [\"T4\"]}, \"Subject\": {\"text\": [[\"a patient with metastatic renal cell carcinoma\"]], \"start\": [[92]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"combination therapy with interferon-alpha and interleukin-2\"]], \"start\": [[29]], \"entity_id\": [\"T5\"], \"Disorder\": {\"text\": [[\"metastatic renal cell carcinoma\"]], \"start\": [[107]], \"entity_id\": [\"T8\"]}, \"Drug\": {\"text\": [[\"interferon-alpha\"], [\"interleukin-2\"]], \"start\": [[54], [75]], \"entity_id\": [\"T9\", \"T10\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"combination\"]], \"start\": [[29]], \"entity_id\": [\"T11\"]}, \"Drug\": {\"text\": [[\"interferon-alpha\"], [\"interleukin-2\"]], \"start\": [[54], [75]], \"entity_id\": [\"T9\", \"T10\"]}}]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[15]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"Metoclopramide\"]], \"start\": [[0]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"Metoclopramide\"]], \"start\": [[0]], \"entity_id\": [\"T6\"]}}, \"Effect\": {\"text\": [[\"parkinsonism\"]], \"start\": [[23]], \"entity_id\": [\"T5\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"followed by\"]], \"start\": [[90]], \"entity_id\": [\"T10\"]}, \"Subject\": {\"text\": [[\"12 year old patient with atrial flutter\"]], \"start\": [[2]], \"entity_id\": [\"T5\"], \"Age\": {\"text\": [[\"12 year old\"]], \"start\": [[2]], \"entity_id\": [\"T11\"]}}, \"Treatment\": {\"text\": [[\"intravenous adenosine\"]], \"start\": [[64]], \"entity_id\": [\"T7\"], \"Drug\": {\"text\": [[\"adenosine\"]], \"start\": [[76]], \"entity_id\": [\"T12\"]}, \"Route\": {\"text\": [[\"intravenous\"]], \"start\": [[64]], \"entity_id\": [\"T13\"]}, \"Disorder\": {\"text\": [[\"atrial flutter\"]], \"start\": [[27]], \"entity_id\": [\"T14\"]}}, \"Effect\": {\"text\": [[\"acceleration of the heart rate to a potentially dangerous arrhythmia\"]], \"start\": [[102]], \"entity_id\": [\"T9\"]}, \"Speculated\": {\"text\": [[\"potentially\"]], \"start\": [[138]], \"entity_id\": [\"T8\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"receiving\"]], \"start\": [[31]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"gefitinib\"]], \"start\": [[41]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"gefitinib\"]], \"start\": [[41]], \"entity_id\": [\"T9\"]}}, \"Subject\": {\"text\": [[\"patients\"]], \"start\": [[22]], \"entity_id\": [\"T7\"]}, \"Effect\": {\"text\": [[\"erlotinib pulmonary toxicity.\"]], \"start\": [[175]], \"entity_id\": [\"T8\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"hospitalized\"]], \"start\": [[75]], \"entity_id\": [\"T7\"]}, \"Treatment\": {\"text\": [[\"Eleven days after increase of the trimipramine dosage to 100 mg/d\"]], \"start\": [[0]], \"entity_id\": [\"T5\"], \"Time_elapsed\": {\"text\": [[\"Eleven days\"]], \"start\": [[0]], \"entity_id\": [\"T10\"]}, \"Dosage\": {\"text\": [[\"100 mg/d\"]], \"start\": [[57]], \"entity_id\": [\"T11\"]}, \"Drug\": {\"text\": [[\"trimipramine\"]], \"start\": [[34]], \"entity_id\": [\"T12\"]}}, \"Subject\": {\"text\": [[\"she\"]], \"start\": [[67]], \"entity_id\": [\"T6\"], \"Gender\": {\"text\": [[\"she\"]], \"start\": [[67]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"seizures suggesting a secondary generalized grand-mal episode\"]], \"start\": [[99]], \"entity_id\": [\"T8\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"suffered\"]], \"start\": [[52]], \"entity_id\": [\"T10\"]}, \"Subject\": {\"text\": [[\"patient with diabetic rubeosis\"]], \"start\": [[17]], \"entity_id\": [\"T5\"]}, \"Effect\": {\"text\": [[\"acute retinal ischemic change and stroke\"]], \"start\": [[66]], \"entity_id\": [\"T7\"]}, \"Treatment\": {\"text\": [[\"intravitreal injection of bevacizumab\"]], \"start\": [[113]], \"entity_id\": [\"T9\"], \"Disorder\": {\"text\": [[\"diabetic rubeosis\"]], \"start\": [[30]], \"entity_id\": [\"T11\"]}, \"Drug\": {\"text\": [[\"bevacizumab\"]], \"start\": [[139]], \"entity_id\": [\"T8\"]}, \"Route\": {\"text\": [[\"intravitreal injection\"]], \"start\": [[113]], \"entity_id\": [\"T12\"]}}, \"Severity\": {\"text\": [[\"acute\"]], \"start\": [[66]], \"entity_id\": [\"T13\"], \"value\": \"High\"}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"caused by\"]], \"start\": [[25]], \"entity_id\": [\"T6\"]}, \"Effect\": {\"text\": [[\"Stevens-Johnson syndrome\"]], \"start\": [[0]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"antiretroviral drug nevirapine\"]], \"start\": [[39]], \"entity_id\": [\"T7\"], \"Drug\": {\"text\": [[\"nevirapine\"]], \"start\": [[59]], \"entity_id\": [\"T8\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"after\"]], \"start\": [[105]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"an initial d-penicillamine therapy\"]], \"start\": [[111]], \"entity_id\": [\"T6\"], \"Disorder\": {\"text\": [[\"WD\"]], \"start\": [[93]], \"entity_id\": [\"T9\"]}, \"Drug\": {\"text\": [[\"d-penicillamine\"]], \"start\": [[122]], \"entity_id\": [\"T10\"]}}, \"Subject\": {\"text\": [[\"WD patients\"]], \"start\": [[93]], \"entity_id\": [\"T7\"]}, \"Effect\": {\"text\": [[\"acute generalized dystonia with brainstem and thalamic lesions\"]], \"start\": [[17]], \"entity_id\": [\"T8\"]}, \"Speculated\": {\"text\": [[\"may occur\"]], \"start\": [[80]], \"entity_id\": [\"T11\"], \"value\": true}, \"Severity\": {\"text\": [[\"acute\"]], \"start\": [[17]], \"entity_id\": [\"T12\"], \"value\": \"High\"}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[148]], \"entity_id\": [\"T8\"]}, \"Treatment\": {\"text\": [[\"TMP-SMX\"]], \"start\": [[140]], \"entity_id\": [\"T7\"], \"Drug\": {\"text\": [[\"TMP-SMX\"]], \"start\": [[140]], \"entity_id\": [\"T13\"]}}, \"Effect\": {\"text\": [[\"hepatotoxicity\"]], \"start\": [[156]], \"entity_id\": [\"T9\"]}, \"Subject\": {\"text\": [[\"pediatric cases\"]], \"start\": [[121]], \"entity_id\": [\"T10\"], \"Age\": {\"text\": [[\"pediatric\"]], \"start\": [[121]], \"entity_id\": [\"T12\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Potential_therapeutic_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Potential_therapeutic_event\", \"Trigger\": {\"text\": [[\"requires\"]], \"start\": [[28]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"complex and longer treatment with alternative substances\"]], \"start\": [[42]], \"entity_id\": [\"T6\"], \"Disorder\": {\"text\": [[\"Drug resistant tuberculosis\"]], \"start\": [[0]], \"entity_id\": [\"T4\"]}, \"Drug\": {\"text\": [[\"substances\"]], \"start\": [[88]], \"entity_id\": [\"T7\"]}, \"Duration\": {\"text\": [[\"complex and longer treatment\"]], \"start\": [[42]], \"entity_id\": [\"T8\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"in\"]], \"start\": [[43]], \"entity_id\": [\"T8\"]}, \"Effect\": {\"text\": [[\"Intracranial haemorrhage from a meningioma\"]], \"start\": [[0]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"a patient\"]], \"start\": [[46]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"aspirin\"]], \"start\": [[66]], \"entity_id\": [\"T9\"], \"Drug\": {\"text\": [[\"aspirin\"]], \"start\": [[66]], \"entity_id\": [\"T7\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"occurred\"]], \"start\": [[79]], \"entity_id\": [\"T4\"]}, \"Effect\": {\"text\": [[\"fixed drug eruption\"]], \"start\": [[54]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"during omeprazole treatment\"]], \"start\": [[88]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"omeprazole\"]], \"start\": [[95]], \"entity_id\": [\"T6\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"complained\"]], \"start\": [[108]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"A 43-year-old male alcoholic\"]], \"start\": [[8]], \"entity_id\": [\"T3\"], \"Age\": {\"text\": [[\"43-year-old\"]], \"start\": [[10]], \"entity_id\": [\"T7\"]}, \"Gender\": {\"text\": [[\"male\"]], \"start\": [[22]], \"entity_id\": [\"T8\"]}}, \"Treatment\": {\"text\": [[\"completely abstinent with cyanamide treatment for 5 years\"]], \"start\": [[46]], \"entity_id\": [\"T4\"], \"Disorder\": {\"text\": [[\"alcoholic\"]], \"start\": [[27]], \"entity_id\": [\"T9\"]}, \"Drug\": {\"text\": [[\"cyanamide\"]], \"start\": [[72]], \"entity_id\": [\"T10\"]}, \"Duration\": {\"text\": [[\"5 years\"]], \"start\": [[96]], \"entity_id\": [\"T11\"]}}, \"Effect\": {\"text\": [[\"general fatigue\"]], \"start\": [[122]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"to\"]], \"start\": [[25]], \"entity_id\": [\"T4\"]}, \"Effect\": {\"text\": [[\"Delayed hypersensitivity\"]], \"start\": [[0]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"flurbiprofen\"]], \"start\": [[28]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"flurbiprofen\"]], \"start\": [[28]], \"entity_id\": [\"T6\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[12]], \"entity_id\": [\"T5\"]}, \"Effect\": {\"text\": [[\"ataxia\"]], \"start\": [[20]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"Propafenone\"]], \"start\": [[0]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"Propafenone\"]], \"start\": [[0]], \"entity_id\": [\"T8\"]}}, \"Subject\": {\"text\": [[\"three cases\"]], \"start\": [[38]], \"entity_id\": [\"T6\"], \"Population\": {\"text\": [[\"three\"]], \"start\": [[38]], \"entity_id\": [\"T7\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"consistent with\"]], \"start\": [[85]], \"entity_id\": [\"T12\"]}, \"Treatment\": {\"text\": [[\"Delavirdine and efavirenz (but not nevirapine)\"]], \"start\": [[0]], \"entity_id\": [\"T10\"], \"Drug\": {\"text\": [[\"Delavirdine\"], [\"efavirenz\"]], \"start\": [[0], [16]], \"entity_id\": [\"T14\", \"T13\"]}}, \"Effect\": {\"text\": [[\"clinical hazards\"]], \"start\": [[101]], \"entity_id\": [\"T11\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[32]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"UFT\"]], \"start\": [[28]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"UFT\"]], \"start\": [[28]], \"entity_id\": [\"T6\"]}}, \"Effect\": {\"text\": [[\"scleroderma-like reaction\"]], \"start\": [[40]], \"entity_id\": [\"T4\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induce\"]], \"start\": [[36]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"roxithromycin and betamethasone\"]], \"start\": [[4]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"roxithromycin\"], [\"betamethasone\"]], \"start\": [[4], [22]], \"entity_id\": [\"T8\", \"T9\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"and\"]], \"start\": [[18]], \"entity_id\": [\"T10\"]}, \"Drug\": {\"text\": [[\"roxithromycin\"], [\"betamethasone\"]], \"start\": [[4], [22]], \"entity_id\": [\"T8\", \"T9\"]}}]}, \"Effect\": {\"text\": [[\"acute pancreatitis\"]], \"start\": [[43]], \"entity_id\": [\"T6\"]}, \"Speculated\": {\"text\": [[\"?\"]], \"start\": [[61]], \"entity_id\": [\"T7\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"develop\"]], \"start\": [[57]], \"entity_id\": [\"T6\"]}, \"Subject\": {\"text\": [[\"Up to four percent of patients\"]], \"start\": [[0]], \"entity_id\": [\"T3\"], \"Population\": {\"text\": [[\"Up to four percent\"]], \"start\": [[0]], \"entity_id\": [\"T7\"]}}, \"Treatment\": {\"text\": [[\"imatinib\"]], \"start\": [[44]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"imatinib\"]], \"start\": [[44]], \"entity_id\": [\"T8\"]}}, \"Effect\": {\"text\": [[\"hepatotoxicity\"]], \"start\": [[65]], \"entity_id\": [\"T5\"]}, \"Speculated\": {\"text\": [[\"may\"]], \"start\": [[53]], \"entity_id\": [\"T9\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[33]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"fluvoxamine\"]], \"start\": [[49]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"fluvoxamine\"]], \"start\": [[49]], \"entity_id\": [\"T6\"]}}, \"Effect\": {\"text\": [[\"Schneiderian first-rank symptoms\"]], \"start\": [[0]], \"entity_id\": [\"T5\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"after\"]], \"start\": [[49]], \"entity_id\": [\"T11\"]}, \"Effect\": {\"text\": [[\"Peripheral and optic neuropathy\", \"lactic acidosis after several weeks (median 6 wks), and serotonin syndrome after several days (median 4 days)\"]], \"start\": [[0, 106]], \"entity_id\": [\"T10\"]}, \"Treatment\": {\"text\": [[\"several months of linezolid therapy (median 5 mo)\"]], \"start\": [[55]], \"entity_id\": [\"T12\"], \"Drug\": {\"text\": [[\"linezolid\"]], \"start\": [[73]], \"entity_id\": [\"T14\"]}, \"Time_elapsed\": {\"text\": [[\"several months\"]], \"start\": [[55]], \"entity_id\": [\"T15\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[11]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"Muzolimine\"]], \"start\": [[0]], \"entity_id\": [\"T4\"], \"Dosage\": {\"text\": [[\"Muzolimine\"]], \"start\": [[0]], \"entity_id\": [\"T7\"]}}, \"Effect\": {\"text\": [[\"neuromyeloencephalopathy\"]], \"start\": [[26]], \"entity_id\": [\"T6\"]}, \"Severity\": {\"text\": [[\"severe\"]], \"start\": [[19]], \"entity_id\": [\"T8\"], \"value\": \"High\"}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"with\"]], \"start\": [[34]], \"entity_id\": [\"T6\"]}, \"Effect\": {\"text\": [[\"peripheral neuropathy\"]], \"start\": [[12]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"5-FU\"]], \"start\": [[39]], \"entity_id\": [\"T7\"], \"Drug\": {\"text\": [[\"5-FU\"]], \"start\": [[39]], \"entity_id\": [\"T8\"]}}, \"Speculated\": {\"text\": [[\"rare\"]], \"start\": [[47]], \"entity_id\": [\"T9\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"produces\"]], \"start\": [[22]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"danazol\"]], \"start\": [[14]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"danazol\"]], \"start\": [[14]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"hepatocellular damage\"]], \"start\": [[31]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"10% of women\"]], \"start\": [[70]], \"entity_id\": [\"T6\"], \"Population\": {\"text\": [[\"10%\"]], \"start\": [[70]], \"entity_id\": [\"T7\"]}, \"Gender\": {\"text\": [[\"women\"]], \"start\": [[77]], \"entity_id\": [\"T8\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"after\"]], \"start\": [[103]], \"entity_id\": [\"T7\"]}, \"Effect\": {\"text\": [[\"typical symptoms of Charles-Bonnet syndrome (CBS)\"]], \"start\": [[25]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"patients with severe AMD\"]], \"start\": [[78]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"intravitreal Avastin-injections\"]], \"start\": [[109]], \"entity_id\": [\"T8\"], \"Drug\": {\"text\": [[\"Avastin\"]], \"start\": [[122]], \"entity_id\": [\"T10\"]}, \"Route\": {\"text\": [[\"intravitreal\", \"injections\"]], \"start\": [[109, 130]], \"entity_id\": [\"T11\"]}, \"Disorder\": {\"text\": [[\"AMD\"]], \"start\": [[99]], \"entity_id\": [\"T12\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"side effects\"]], \"start\": [[71]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"imipenem/cilastatin\"]], \"start\": [[26]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"cilastatin\"], [\"imipenem\"]], \"start\": [[35], [26]], \"entity_id\": [\"T7\", \"T8\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"/\"]], \"start\": [[34]], \"entity_id\": [\"T9\"]}, \"Drug\": {\"text\": [[\"imipenem\"], [\"cilastatin\"]], \"start\": [[26], [35]], \"entity_id\": [\"T8\", \"T7\"]}}]}, \"Effect\": {\"text\": [[\"Proconvulsive tendency\"]], \"start\": [[0]], \"entity_id\": [\"T5\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"developed\"]], \"start\": [[86]], \"entity_id\": [\"T10\"]}, \"Subject\": {\"text\": [[\"49-year-old man with Crohn's disease\"]], \"start\": [[2]], \"entity_id\": [\"T9\"], \"Age\": {\"text\": [[\"49-year-old\"]], \"start\": [[2]], \"entity_id\": [\"T13\"]}, \"Gender\": {\"text\": [[\"man\"]], \"start\": [[14]], \"entity_id\": [\"T14\"]}}, \"Effect\": {\"text\": [[\"worsening respiratory distress and fever.\"]], \"start\": [[96]], \"entity_id\": [\"T11\"]}, \"Treatment\": {\"text\": [[\"prednisone and mesalamine (5-ASA)\"]], \"start\": [[52]], \"entity_id\": [\"T12\"], \"Disorder\": {\"text\": [[\"Crohn's disease\"]], \"start\": [[23]], \"entity_id\": [\"T16\"]}, \"Drug\": {\"text\": [[\"mesalamine\"], [\"prednisone\"]], \"start\": [[67], [52]], \"entity_id\": [\"T19\", \"T20\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"and\"]], \"start\": [[63]], \"entity_id\": [\"T18\"]}, \"Drug\": {\"text\": [[\"prednisone\"], [\"mesalamine\"]], \"start\": [[52], [67]], \"entity_id\": [\"T20\", \"T19\"]}}]}, \"Severity\": {\"text\": [[\"worsening\"]], \"start\": [[96]], \"entity_id\": [\"T17\"], \"value\": \"Medium\"}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"use\"]], \"start\": [[86]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"gabapentin\"]], \"start\": [[93]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"gabapentin\"]], \"start\": [[93]], \"entity_id\": [\"T7\"]}}, \"Effect\": {\"text\": [[\"a significant type of morbidity\"]], \"start\": [[37]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"This case\"]], \"start\": [[11]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"resulting\"]], \"start\": [[15]], \"entity_id\": [\"T4\"]}, \"Subject\": {\"text\": [[\"elderly patients\"]], \"start\": [[135]], \"entity_id\": [\"T3\"], \"Age\": {\"text\": [[\"elderly\"]], \"start\": [[135]], \"entity_id\": [\"T7\"]}}, \"Effect\": {\"text\": [[\"Acute delirium\"]], \"start\": [[0]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"levofloxacin\"]], \"start\": [[30]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"levofloxacin\"]], \"start\": [[30]], \"entity_id\": [\"T9\"]}}, \"Speculated\": {\"text\": [[\"exceedingly rare\"]], \"start\": [[57]], \"entity_id\": [\"T8\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[49]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"raloxifene\"]], \"start\": [[38]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"raloxifene\"]], \"start\": [[38]], \"entity_id\": [\"T6\"]}}, \"Effect\": {\"text\": [[\"aggravation of nonalcoholic steatohepatitis\"]], \"start\": [[60]], \"entity_id\": [\"T5\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"complained\"]], \"start\": [[55]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"The day after methotrexate administration\"]], \"start\": [[0]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"methotrexate\"]], \"start\": [[14]], \"entity_id\": [\"T8\"]}, \"Time_elapsed\": {\"text\": [[\"The day after\"]], \"start\": [[0]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"severe back pain and urinary retention\"]], \"start\": [[69]], \"entity_id\": [\"T7\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"secondary\"]], \"start\": [[19]], \"entity_id\": [\"T5\"]}, \"Effect\": {\"text\": [[\"Pulmonary toxicity\"]], \"start\": [[0]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"procarbazine\"]], \"start\": [[32]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"procarbazine\"]], \"start\": [[32]], \"entity_id\": [\"T6\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"following\"]], \"start\": [[106]], \"entity_id\": [\"T5\"]}, \"Effect\": {\"text\": [[\"aortic wall in this case was damaged\"]], \"start\": [[48]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"irradiation and Bleomycin treatment.\"]], \"start\": [[116]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"Bleomycin\"]], \"start\": [[132]], \"entity_id\": [\"T6\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"caused\"]], \"start\": [[31]], \"entity_id\": [\"T9\"]}, \"Effect\": {\"text\": [[\"PPE\"]], \"start\": [[27]], \"entity_id\": [\"T8\"]}, \"Treatment\": {\"text\": [[\"cytarabine\"]], \"start\": [[41]], \"entity_id\": [\"T10\"], \"Drug\": {\"text\": [[\"cytarabine\"]], \"start\": [[41]], \"entity_id\": [\"T11\"]}}, \"Negated\": {\"text\": [[\"not\"]], \"start\": [[57]], \"entity_id\": [\"T12\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"may not reduce\"]], \"start\": [[134]], \"entity_id\": [\"T6\"]}, \"Effect\": {\"text\": [[\"endometrial lesions\"], [\"carcinoma\"]], \"start\": [[163], [194]], \"entity_id\": [\"T7\", \"T8\"]}, \"Treatment\": {\"text\": [[\"addition of progestogens to tamoxifen\"]], \"start\": [[96]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"progestogens\"], [\"tamoxifen\"]], \"start\": [[108], [124]], \"entity_id\": [\"T10\", \"T11\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"addition\"]], \"start\": [[96]], \"entity_id\": [\"T12\"]}, \"Drug\": {\"text\": [[\"progestogens\"], [\"tamoxifen\"]], \"start\": [[108], [124]], \"entity_id\": [\"T10\", \"T11\"]}}]}, \"Speculated\": {\"text\": [[\"may\"]], \"start\": [[134]], \"entity_id\": [\"T9\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"following\"]], \"start\": [[35]], \"entity_id\": [\"T4\"]}, \"Effect\": {\"text\": [[\"Inappropriate antidiuretic hormone\"]], \"start\": [[0]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"adenine arabinoside\"]], \"start\": [[45]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"adenine arabinoside\"]], \"start\": [[45]], \"entity_id\": [\"T6\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[11]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"Ampicillin\"]], \"start\": [[0]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"Ampicillin\"]], \"start\": [[0]], \"entity_id\": [\"T6\"]}}, \"Effect\": {\"text\": [[\"seizures\"]], \"start\": [[22]], \"entity_id\": [\"T5\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"receiving\"]], \"start\": [[83]], \"entity_id\": [\"T7\"]}, \"Effect\": {\"text\": [[\"fibrosing alveolitis\"]], \"start\": [[22]], \"entity_id\": [\"T4\"]}, \"Subject\": {\"text\": [[\"a patient\"]], \"start\": [[73]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"amiodarone which responded to corticosteroid therapy\"]], \"start\": [[93]], \"entity_id\": [\"T8\"], \"Drug\": {\"text\": [[\"amiodarone\"], [\"corticosteroid\"]], \"start\": [[93], [123]], \"entity_id\": [\"T5\", \"T9\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"responded\"]], \"start\": [[110]], \"entity_id\": [\"T3\"]}, \"Drug\": {\"text\": [[\"amiodarone\"], [\"corticosteroid\"]], \"start\": [[93], [123]], \"entity_id\": [\"T5\", \"T9\"]}}]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[11]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"Furosemide\"]], \"start\": [[0]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"Furosemide\"]], \"start\": [[0]], \"entity_id\": [\"T7\"]}}, \"Effect\": {\"text\": [[\"fever\"]], \"start\": [[22]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"during\"]], \"start\": [[67]], \"entity_id\": [\"T5\"]}, \"Effect\": {\"text\": [[\"Thymic enlargement\"]], \"start\": [[0]], \"entity_id\": [\"T3\"]}, \"Subject\": {\"text\": [[\"a patient with juvenile idiopathic arthritis\"]], \"start\": [[22]], \"entity_id\": [\"T4\"], \"Age\": {\"text\": [[\"juvenile\"]], \"start\": [[37]], \"entity_id\": [\"T2\"]}}, \"Treatment\": {\"text\": [[\"etanercept\"]], \"start\": [[74]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"etanercept\"]], \"start\": [[74]], \"entity_id\": [\"T8\"]}, \"Disorder\": {\"text\": [[\"idiopathic arthritis\"]], \"start\": [[46]], \"entity_id\": [\"T1\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[21]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"methylene blue\"]], \"start\": [[6]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"methylene blue\"]], \"start\": [[6]], \"entity_id\": [\"T7\"]}}, \"Effect\": {\"text\": [[\"serotonin toxicity\"]], \"start\": [[32]], \"entity_id\": [\"T6\"]}, \"Severity\": {\"text\": [[\"Fatal\"]], \"start\": [[0]], \"entity_id\": [\"T8\"], \"value\": \"High\"}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[9]], \"entity_id\": [\"T3\"]}, \"Effect\": {\"text\": [[\"ARF\", \"anuria\", \"renal failure\"]], \"start\": [[17, 80, 103]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"Mannitol\"]], \"start\": [[0]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"Mannitol\"]], \"start\": [[0]], \"entity_id\": [\"T6\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"while\"]], \"start\": [[96]], \"entity_id\": [\"T5\"]}, \"Effect\": {\"text\": [[\"recurrent (stuttering) priapism\"]], \"start\": [[25]], \"entity_id\": [\"T6\"]}, \"Subject\": {\"text\": [[\"a patient with protein C deficiency\"]], \"start\": [[60]], \"entity_id\": [\"T7\"]}, \"Treatment\": {\"text\": [[\"maintained on Warfarin therapy\"]], \"start\": [[102]], \"entity_id\": [\"T8\"], \"Disorder\": {\"text\": [[\"protein C deficiency\"]], \"start\": [[75]], \"entity_id\": [\"T9\"]}, \"Drug\": {\"text\": [[\"Warfarin\"]], \"start\": [[116]], \"entity_id\": [\"T10\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[39]], \"entity_id\": [\"T6\"]}, \"Effect\": {\"text\": [[\"Angioedema and maculopapular eruptions\"]], \"start\": [[0]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"carbamazepine administration.\"]], \"start\": [[55]], \"entity_id\": [\"T7\"], \"Drug\": {\"text\": [[\"carbamazepine\"]], \"start\": [[55]], \"entity_id\": [\"T8\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"result\"]], \"start\": [[29]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"hepatitis B vaccination\"]], \"start\": [[39]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"hepatitis B vaccination.\"]], \"start\": [[39]], \"entity_id\": [\"T6\"]}}, \"Effect\": {\"text\": [[\"Mental nerve neuropathy\"]], \"start\": [[0]], \"entity_id\": [\"T5\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"developed\"]], \"start\": [[110]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"a premenopausal woman\"]], \"start\": [[12]], \"entity_id\": [\"T3\"], \"Gender\": {\"text\": [[\"woman\"]], \"start\": [[28]], \"entity_id\": [\"T9\"]}, \"Age\": {\"text\": [[\"premenopausal\"]], \"start\": [[14]], \"entity_id\": [\"T10\"]}}, \"Treatment\": {\"text\": [[\"tamoxifen\"]], \"start\": [[52]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"tamoxifen\"]], \"start\": [[52]], \"entity_id\": [\"T12\"]}, \"Disorder\": {\"text\": [[\"in situ ductal carcinoma\"]], \"start\": [[84]], \"entity_id\": [\"T13\"]}}, \"Effect\": {\"text\": [[\"endometriosis\"]], \"start\": [[120]], \"entity_id\": [\"T7\"]}, \"Severity\": {\"text\": [[\"requiring surgery\"]], \"start\": [[134]], \"entity_id\": [\"T8\"], \"value\": \"Medium\"}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"in the setting of\"]], \"start\": [[39]], \"entity_id\": [\"T6\"]}, \"Effect\": {\"text\": [[\"Disseminated cellulitic cryptococcosis\"]], \"start\": [[0]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"prednisone monotherapy\"]], \"start\": [[57]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"prednisone\"]], \"start\": [[57]], \"entity_id\": [\"T7\"]}, \"Disorder\": {\"text\": [[\"pemphigus vulgaris\"]], \"start\": [[84]], \"entity_id\": [\"T8\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"developed\"]], \"start\": [[108]], \"entity_id\": [\"T6\"]}, \"Subject\": {\"text\": [[\"a 63 year old woman with a suppurative mediastinitis\"]], \"start\": [[12]], \"entity_id\": [\"T3\"], \"Age\": {\"text\": [[\"63 year old\"]], \"start\": [[14]], \"entity_id\": [\"T8\"]}, \"Gender\": {\"text\": [[\"woman\"]], \"start\": [[26]], \"entity_id\": [\"T9\"]}}, \"Treatment\": {\"text\": [[\"continuous PI irrigation\"]], \"start\": [[79]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"PI\"]], \"start\": [[90]], \"entity_id\": [\"T10\"]}, \"Disorder\": {\"text\": [[\"suppurative mediastinitis\"]], \"start\": [[39]], \"entity_id\": [\"T11\"]}, \"Route\": {\"text\": [[\"irrigation\"]], \"start\": [[93]], \"entity_id\": [\"T12\"]}}, \"Effect\": {\"text\": [[\"acute oliguric renal failure\"]], \"start\": [[121]], \"entity_id\": [\"T7\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"had\"]], \"start\": [[28]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"antineoplastic therapy with adriamycin and cisplatin.\"]], \"start\": [[61]], \"entity_id\": [\"T5\"], \"Drug\": {\"text\": [[\"adriamycin\"], [\"cisplatin\"]], \"start\": [[89], [104]], \"entity_id\": [\"T11\", \"T12\"]}, \"Disorder\": {\"text\": [[\"epilepsy\"]], \"start\": [[19]], \"entity_id\": [\"T14\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"and\"]], \"start\": [[100]], \"entity_id\": [\"T13\"]}, \"Drug\": {\"text\": [[\"adriamycin\"], [\"cisplatin\"]], \"start\": [[89], [104]], \"entity_id\": [\"T11\", \"T12\"]}}]}, \"Subject\": {\"text\": [[\"A young woman with epilepsy\"]], \"start\": [[0]], \"entity_id\": [\"T6\"], \"Age\": {\"text\": [[\"young\"]], \"start\": [[2]], \"entity_id\": [\"T8\"]}, \"Gender\": {\"text\": [[\"woman\"]], \"start\": [[8]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"tonic-clonic seizures\"]], \"start\": [[32]], \"entity_id\": [\"T7\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[56]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"This patient\"]], \"start\": [[13]], \"entity_id\": [\"T3\"]}, \"Effect\": {\"text\": [[\"rhabdomyolysis\"]], \"start\": [[28]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"sertraline\"]], \"start\": [[67]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"sertraline\"]], \"start\": [[67]], \"entity_id\": [\"T8\"]}}, \"Speculated\": {\"text\": [[\"probably\"]], \"start\": [[47]], \"entity_id\": [\"T7\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"treated\"]], \"start\": [[51]], \"entity_id\": [\"T11\"]}, \"Effect\": {\"text\": [[\"Nephrotic syndrome\"]], \"start\": [[0]], \"entity_id\": [\"T7\"]}, \"Subject\": {\"text\": [[\"a multiple sclerosis patient\"]], \"start\": [[22]], \"entity_id\": [\"T9\"]}, \"Treatment\": {\"text\": [[\"interferon beta 1a\"]], \"start\": [[64]], \"entity_id\": [\"T10\"], \"Drug\": {\"text\": [[\"interferon beta 1a\"]], \"start\": [[64]], \"entity_id\": [\"T12\"]}, \"Disorder\": {\"text\": [[\"multiple sclerosis\"]], \"start\": [[24]], \"entity_id\": [\"T13\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"related to\"]], \"start\": [[34]], \"entity_id\": [\"T8\"]}, \"Treatment\": {\"text\": [[\"cefuroxime\"]], \"start\": [[45]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"cefuroxime\"]], \"start\": [[45]], \"entity_id\": [\"T10\"]}}, \"Effect\": {\"text\": [[\"DIAN\"]], \"start\": [[16]], \"entity_id\": [\"T7\"]}, \"Subject\": {\"text\": [[\"our patient\"]], \"start\": [[3]], \"entity_id\": [\"T9\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"developed\"]], \"start\": [[103]], \"entity_id\": [\"T4\"]}, \"Subject\": {\"text\": [[\"a nonatopic 17-year-old girl with bronchial asthma and aspirin intolerance\"]], \"start\": [[24]], \"entity_id\": [\"T3\"], \"Disorder\": {\"text\": [[\"nonatopic\"], [\"aspirin intolerance\"]], \"start\": [[26], [79]], \"entity_id\": [\"T7\", \"T11\"]}, \"Age\": {\"text\": [[\"17-year-old\"]], \"start\": [[36]], \"entity_id\": [\"T8\"]}, \"Gender\": {\"text\": [[\"girl\"]], \"start\": [[48]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"a dramatic anaphylactic reaction\"]], \"start\": [[113]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"oral prednisone\"]], \"start\": [[149]], \"entity_id\": [\"T6\"], \"Route\": {\"text\": [[\"oral\"]], \"start\": [[149]], \"entity_id\": [\"T12\"]}, \"Drug\": {\"text\": [[\"prednisone\"]], \"start\": [[154]], \"entity_id\": [\"T13\"]}, \"Disorder\": {\"text\": [[\"bronchial asthma\"]], \"start\": [[58]], \"entity_id\": [\"T14\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"developed\"]], \"start\": [[67]], \"entity_id\": [\"T4\"]}, \"Subject\": {\"text\": [[\"A 10-year-old white girl with bilateral optic glioma\"]], \"start\": [[14]], \"entity_id\": [\"T3\"], \"Age\": {\"text\": [[\"10-year-old\"]], \"start\": [[16]], \"entity_id\": [\"T7\"]}, \"Gender\": {\"text\": [[\"girl\"]], \"start\": [[34]], \"entity_id\": [\"T8\"]}, \"Race\": {\"text\": [[\"white\"]], \"start\": [[28]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"hypersensitivity reaction\"]], \"start\": [[79]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"carboplatin after nine courses\"]], \"start\": [[108]], \"entity_id\": [\"T6\"], \"Disorder\": {\"text\": [[\"bilateral optic glioma\"]], \"start\": [[44]], \"entity_id\": [\"T10\"]}, \"Drug\": {\"text\": [[\"carboplatin\"]], \"start\": [[108]], \"entity_id\": [\"T11\"]}, \"Duration\": {\"text\": [[\"nine courses\"]], \"start\": [[126]], \"entity_id\": [\"T12\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"when\"]], \"start\": [[45]], \"entity_id\": [\"T9\"]}, \"Subject\": {\"text\": [[\"patients\"]], \"start\": [[101]], \"entity_id\": [\"T7\"]}, \"Effect\": {\"text\": [[\"Liver function should be carefully monitored\"]], \"start\": [[0]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"rifampicin and lopinavir/ritonavir are combined\"]], \"start\": [[50]], \"entity_id\": [\"T8\"], \"Drug\": {\"text\": [[\"rifampicin\"], [\"lopinavir/ritonavir\"]], \"start\": [[50], [65]], \"entity_id\": [\"T12\", \"T13\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"and\"]], \"start\": [[61]], \"entity_id\": [\"T11\"]}, \"Drug\": {\"text\": [[\"rifampicin\"], [\"lopinavir/ritonavir\"]], \"start\": [[50], [65]], \"entity_id\": [\"T12\", \"T13\"]}}]}, \"Speculated\": {\"text\": [[\"monitored\"]], \"start\": [[35]], \"entity_id\": [\"T10\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Potential_therapeutic_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Potential_therapeutic_event\", \"Trigger\": {\"text\": [[\"initiation\"]], \"start\": [[179]], \"entity_id\": [\"T7\"]}, \"Subject\": {\"text\": [[\"three patients\"]], \"start\": [[10]], \"entity_id\": [\"T3\"], \"Population\": {\"text\": [[\"three\"]], \"start\": [[10]], \"entity_id\": [\"T8\"]}}, \"Effect\": {\"text\": [[\"profound reduction in plasma HDL cholesterol and apolipoprotein AI levels\"]], \"start\": [[90]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"rosiglitazone therapy\"]], \"start\": [[193]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"rosiglitazone\"]], \"start\": [[193]], \"entity_id\": [\"T9\"]}, \"Time_elapsed\": {\"text\": [[\"soon after\"]], \"start\": [[164]], \"entity_id\": [\"T10\"]}, \"Disorder\": {\"text\": [[\"preexisting diabetic dyslipidemia\"]], \"start\": [[42]], \"entity_id\": [\"T11\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"precipitate\"]], \"start\": [[43]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"fluvoxamine\"]], \"start\": [[27]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"fluvoxamine\"]], \"start\": [[27]], \"entity_id\": [\"T7\"]}}, \"Effect\": {\"text\": [[\"Schneiderian first-rank symptoms\"]], \"start\": [[55]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"some susceptible patients\"]], \"start\": [[91]], \"entity_id\": [\"T6\"]}, \"Speculated\": {\"text\": [[\"suggests\"]], \"start\": [[13]], \"entity_id\": [\"T8\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[9]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"Warfarin\"]], \"start\": [[0]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"Warfarin\"]], \"start\": [[0]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"thoracic aortic dissection\"]], \"start\": [[20]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"an elderly woman\"]], \"start\": [[50]], \"entity_id\": [\"T6\"], \"Age\": {\"text\": [[\"elderly\"]], \"start\": [[53]], \"entity_id\": [\"T7\"]}, \"Gender\": {\"text\": [[\"woman\"]], \"start\": [[61]], \"entity_id\": [\"T8\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"adverse effect\"]], \"start\": [[31]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"first report of an adverse effect of fetal renal circulation\"]], \"start\": [[12]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"maternal ingestion of nimesulide\"], [\"nimesulide\"]], \"start\": [[76], [98]], \"entity_id\": [\"T4\", \"T6\"], \"Drug\": {\"text\": [[\"nimesulide\"]], \"start\": [[98]], \"entity_id\": [\"T8\"]}, \"Route\": {\"text\": [[\"maternal ingestion\"]], \"start\": [[76]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"fetal renal circulation\"]], \"start\": [[49]], \"entity_id\": [\"T7\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"over-anticoagulation\"]], \"start\": [[20]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"warfarin\"]], \"start\": [[61]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"warfarin\"]], \"start\": [[61]], \"entity_id\": [\"T7\"]}}, \"Effect\": {\"text\": [[\"Diarrhea-associated over-anticoagulation\"]], \"start\": [[0]], \"entity_id\": [\"T4\"]}, \"Subject\": {\"text\": [[\"patient\"]], \"start\": [[46]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"developed\"]], \"start\": [[33]], \"entity_id\": [\"T8\"]}, \"Subject\": {\"text\": [[\"A 72-year-old white man\"]], \"start\": [[0]], \"entity_id\": [\"T7\"], \"Age\": {\"text\": [[\"72-year-old\"]], \"start\": [[2]], \"entity_id\": [\"T11\"]}, \"Race\": {\"text\": [[\"white\"]], \"start\": [[14]], \"entity_id\": [\"T12\"]}, \"Gender\": {\"text\": [[\"man\"]], \"start\": [[20]], \"entity_id\": [\"T13\"]}}, \"Effect\": {\"text\": [[\"combative behavior, refused to leave his room, stopped eating, and began falling to the floor\"]], \"start\": [[43]], \"entity_id\": [\"T9\"]}, \"Treatment\": {\"text\": [[\"6 weeks after being given ticlopidine\"]], \"start\": [[137]], \"entity_id\": [\"T10\"], \"Time_elapsed\": {\"text\": [[\"6 weeks\"]], \"start\": [[137]], \"entity_id\": [\"T14\"]}, \"Drug\": {\"text\": [[\"ticlopidine\"]], \"start\": [[163]], \"entity_id\": [\"T15\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"give rise\"]], \"start\": [[77]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"gold\"]], \"start\": [[31]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"gold\"]], \"start\": [[31]], \"entity_id\": [\"T7\"]}}, \"Effect\": {\"text\": [[\"wide range of skin disturbances, which in many cases do not break out until long after the drug has been withdrawn\"]], \"start\": [[92]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"in the same patient,\"]], \"start\": [[52]], \"entity_id\": [\"T6\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"considered\"]], \"start\": [[32]], \"entity_id\": [\"T8\"]}, \"Treatment\": {\"text\": [[\"Lithium\"]], \"start\": [[0]], \"entity_id\": [\"T5\"], \"Disorder\": {\"text\": [[\"Creutzfeldt-Jakob disease\"]], \"start\": [[46]], \"entity_id\": [\"T7\"]}, \"Drug\": {\"text\": [[\"Lithium\"]], \"start\": [[0]], \"entity_id\": [\"T10\"]}}, \"Effect\": {\"text\": [[\"Lithium neurotoxicity\"]], \"start\": [[0]], \"entity_id\": [\"T6\"]}, \"Speculated\": {\"text\": [[\"should\"]], \"start\": [[22]], \"entity_id\": [\"T9\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"occurred\"]], \"start\": [[67]], \"entity_id\": [\"T6\"]}, \"Effect\": {\"text\": [[\"neuroleptic malignant syndrome\"]], \"start\": [[31]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"amitriptyline and lithium carbonate\"]], \"start\": [[92]], \"entity_id\": [\"T7\"], \"Drug\": {\"text\": [[\"amitriptyline\"], [\"lithium carbonate\"]], \"start\": [[92], [110]], \"entity_id\": [\"T8\", \"T9\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"and\"]], \"start\": [[106]], \"entity_id\": [\"T10\"]}, \"Drug\": {\"text\": [[\"amitriptyline\"], [\"lithium carbonate\"]], \"start\": [[92], [110]], \"entity_id\": [\"T8\", \"T9\"]}}]}, \"Subject\": {\"text\": [[\"a patient\"]], \"start\": [[79]], \"entity_id\": [\"T5\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[66]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"intravenous administration of phenytoin\"]], \"start\": [[82]], \"entity_id\": [\"T6\"], \"Route\": {\"text\": [[\"ntravenous administration\"]], \"start\": [[83]], \"entity_id\": [\"T8\"]}, \"Drug\": {\"text\": [[\"phenytoin\"]], \"start\": [[112]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"soft-tissue injury\"]], \"start\": [[47]], \"entity_id\": [\"T7\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[93]], \"entity_id\": [\"T3\"]}, \"Treatment\": {\"text\": [[\"troglitazone\"]], \"start\": [[80]], \"entity_id\": [\"T4\"], \"Drug\": {\"text\": [[\"troglitazone\"]], \"start\": [[80]], \"entity_id\": [\"T6\"]}}, \"Effect\": {\"text\": [[\"liver injury is insidious and temporally variable\"]], \"start\": [[101]], \"entity_id\": [\"T5\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induce\"]], \"start\": [[65]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"chlorpromazine\"]], \"start\": [[37]], \"entity_id\": [\"T3\"], \"Drug\": {\"text\": [[\"chlorpromazine\"]], \"start\": [[37]], \"entity_id\": [\"T6\"]}}, \"Effect\": {\"text\": [[\"symptoms resembling Parkinson's disease\"]], \"start\": [[72]], \"entity_id\": [\"T5\"]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"induced\"]], \"start\": [[80]], \"entity_id\": [\"T4\"]}, \"Treatment\": {\"text\": [[\"Erythromycin\"]], \"start\": [[0]], \"entity_id\": [\"T7\"], \"Drug\": {\"text\": [[\"Erythromycin\"], [\"lovastatin\"]], \"start\": [[0], [69]], \"entity_id\": [\"T8\", \"T9\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"risk\"]], \"start\": [[61]], \"entity_id\": [\"T10\"]}, \"Drug\": {\"text\": [[\"lovastatin\"], [\"Erythromycin\"]], \"start\": [[69], [0]], \"entity_id\": [\"T9\", \"T8\"]}}]}, \"Effect\": {\"text\": [[\"ncrease the risk of lovastatin-induced rhabdomyolysis\"]], \"start\": [[49]], \"entity_id\": [\"T5\"]}, \"Speculated\": {\"text\": [[\"may\"]], \"start\": [[44]], \"entity_id\": [\"T6\"], \"value\": true}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Potential_therapeutic_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Potential_therapeutic_event\", \"Trigger\": {\"text\": [[\"receive\"]], \"start\": [[60]], \"entity_id\": [\"T5\"]}, \"Treatment\": {\"text\": [[\"intravenous chemotherapy\"]], \"start\": [[68]], \"entity_id\": [\"T6\"], \"Drug\": {\"text\": [[\"chemotherapy\"]], \"start\": [[80]], \"entity_id\": [\"T12\"]}, \"Disorder\": {\"text\": [[\"acute myelogenous leukemia\"]], \"start\": [[97]], \"entity_id\": [\"T13\"]}, \"Route\": {\"text\": [[\"intravenous\"]], \"start\": [[68]], \"entity_id\": [\"T7\"]}}, \"Subject\": {\"text\": [[\"A 23-year-old white male patient\"]], \"start\": [[0]], \"entity_id\": [\"T8\"], \"Age\": {\"text\": [[\"23-year-old\"]], \"start\": [[2]], \"entity_id\": [\"T9\"]}, \"Race\": {\"text\": [[\"white\"]], \"start\": [[14]], \"entity_id\": [\"T10\"]}, \"Gender\": {\"text\": [[\"male\"]], \"start\": [[20]], \"entity_id\": [\"T11\"]}}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"developed\"]], \"start\": [[60]], \"entity_id\": [\"T5\"]}, \"Subject\": {\"text\": [[\"two children with acute lymphocytic leukemia\"]], \"start\": [[11]], \"entity_id\": [\"T4\"], \"Population\": {\"text\": [[\"two\"]], \"start\": [[11]], \"entity_id\": [\"T8\"]}, \"Age\": {\"text\": [[\"children\"]], \"start\": [[15]], \"entity_id\": [\"T9\"]}}, \"Effect\": {\"text\": [[\"leukoencephalopathy\"]], \"start\": [[70]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"administration of a combination of intravenous ara = C and methotrexate during the consolidation phase of chemotherapy\"]], \"start\": [[100]], \"entity_id\": [\"T7\"], \"Disorder\": {\"text\": [[\"acute lymphocytic leukemia\"]], \"start\": [[29]], \"entity_id\": [\"T10\"]}, \"Route\": {\"text\": [[\"intravenous\"]], \"start\": [[135]], \"entity_id\": [\"T12\"]}, \"Drug\": {\"text\": [[\"ara = C\"], [\"methotrexate\"]], \"start\": [[147], [159]], \"entity_id\": [\"T13\", \"T14\"]}, \"Combination\": [{\"event_id\": \"E2\", \"event_type\": \"Combination\", \"Trigger\": {\"text\": [[\"combination\"]], \"start\": [[120]], \"entity_id\": [\"T11\"]}, \"Drug\": {\"text\": [[\"ara = C\"], [\"methotrexate\"]], \"start\": [[147], [159]], \"entity_id\": [\"T13\", \"T14\"]}}]}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"complicating\"]], \"start\": [[14]], \"entity_id\": [\"T12\"]}, \"Subject\": {\"text\": [[\"a breast cancer patient with an impaired renal function\"]], \"start\": [[64]], \"entity_id\": [\"T9\"], \"Disorder\": {\"text\": [[\"an impaired renal function\"]], \"start\": [[93]], \"entity_id\": [\"T1\"]}}, \"Treatment\": {\"text\": [[\"high dose ifosfamide chemotherapy\"]], \"start\": [[27]], \"entity_id\": [\"T10\"], \"Disorder\": {\"text\": [[\"breast cancer\"]], \"start\": [[66]], \"entity_id\": [\"T13\"]}, \"Drug\": {\"text\": [[\"ifosfamide\"]], \"start\": [[37]], \"entity_id\": [\"T14\"]}, \"Route\": {\"text\": [[\"chemotherapy\"]], \"start\": [[48]], \"entity_id\": [\"T16\"]}, \"Dosage\": {\"text\": [[\"high dose\"]], \"start\": [[27]], \"entity_id\": [\"T17\"]}}, \"Effect\": {\"text\": [[\"anuria\"]], \"start\": [[7]], \"entity_id\": [\"T11\"]}, \"Severity\": {\"text\": [[\"Lethal\"]], \"start\": [[0]], \"entity_id\": [\"T15\"], \"value\": \"High\"}}" } ] } ]

[ { "events": [ { "event_id": "E1", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E1\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[75]], \"entity_id\": [\"T6\"]}, \"Effect\": {\"text\": [[\"a delayed, severe maculopathy\"]], \"start\": [[91]], \"entity_id\": [\"T8\"]}, \"Treatment\": {\"text\": [[\"Low dosages of quinacrine used for malaria prophylaxis\"]], \"start\": [[13]], \"entity_id\": [\"T7\"], \"Time_elapsed\": {\"text\": [[\"delayed\"]], \"start\": [[93]], \"entity_id\": [\"T10\"]}, \"Dosage\": {\"text\": [[\"Low dosages\"]], \"start\": [[13]], \"entity_id\": [\"T12\"]}, \"Drug\": {\"text\": [[\"quinacrine\"]], \"start\": [[28]], \"entity_id\": [\"T13\"]}, \"Disorder\": {\"text\": [[\"malaria prophylaxis\"]], \"start\": [[48]], \"entity_id\": [\"T14\"]}}, \"Severity\": {\"text\": [[\"severe\"]], \"start\": [[102]], \"entity_id\": [\"T9\"], \"value\": \"Medium\"}}" }, { "event_id": "E2", "event_type": "Adverse_event", "event_data": "{\"event_id\": \"E2\", \"event_type\": \"Adverse_event\", \"Trigger\": {\"text\": [[\"associated\"]], \"start\": [[75]], \"entity_id\": [\"T6\"]}, \"Treatment\": {\"text\": [[\"Low dosages of quinacrine used for malaria prophylaxis\"]], \"start\": [[13]], \"entity_id\": [\"T7\"], \"Time_elapsed\": {\"text\": [[\"delayed\"]], \"start\": [[93]], \"entity_id\": [\"T10\"]}, \"Dosage\": {\"text\": [[\"Low dosages\"]], \"start\": [[13]], \"entity_id\": [\"T12\"]}, \"Drug\": {\"text\": [[\"quinacrine\"]], \"start\": [[28]], \"entity_id\": [\"T13\"]}, \"Disorder\": {\"text\": [[\"malaria prophylaxis\"]], \"start\": [[48]], \"entity_id\": [\"T14\"]}}, \"Effect\": {\"text\": [[\"chloroquine maculopathy\"]], \"start\": [[144]], \"entity_id\": [\"T15\"]}, \"Subject\": {\"text\": [[\"certain patients.\"]], \"start\": [[171]], \"entity_id\": [\"T5\"]}}" } ] } ]