Talk:Paracrine signaling

message: First off, thanks for your interest in paracrine signaling! We worked tirelessly to produce this page for your educational purposes. This page was created for our Developmental Biology class at our university. In this Wikipedia page, you will find that we described both the types of receptors and pathways of paracrine signaling -in addition to what paracrine signaling is all about,  of course. Moreover, we described how paracrine signaling affects these receptors and pathways, in terms of transcription of genes and the subsequent responsive function of the induced cell. However, you will also read about the aberrant responses when things go wrong (which we all know can result in serious anomalies and malignancies). Please feel free to contribute to the article, whether it be through content or layout editing, and note any changes in this talk page!
We hope you enjoy the page and learn more about the wonderful world of cell-cell communication.
Best,
Developmentalbio (talk) 17:03, 4 April 2013 (UTC)
replies: text: Well, neurotransmission could be classified as such, except nobody does so. JFW | T@lk 15:38, 11 January 2006 (UTC)
thread_title: Untitled

message: The introduction to this article says that autocrine signaling is signaling to other cells of the same type. The Autocrine signalling, on the other hand, says that it's to the same cell, and the definition at Dictionary.com appears to agree with this latter definition. Is the definition given in this article accurate but broader? An out-of-date usage? Just simply incorrect? A correction and/or clarification appears to be in order, but I am not familiar enough with the subject to make the necessary changes. --Icarus (Hi!) 00:33, 21 May 2008 (UTC)
thread_title: Autocrine

message: The article provides very specific summaries of the different pathways involved with paracrine signaling factors, especially the major families that pertain to early developmental processes. The language is very scientific and may not be perfectly clear to the average layperson, and there are several basic concepts that may benefit from further explanation. The introduction section should include a brief overview of how a transcription factor works by binding to the promoter or enhancer of the target gene. Clarify that this protein binding is necessary for attachment of RNA polymerase.  The section on receptor tyrosine kinases might also specify that IP3 is a derivative of the phospholipids in the plasma membrane. Depalmal (talk) 20:29, 13 April 2013 (UTC)
thread_title: Peer Review for Developmental Biology Course

message: <Cohen M.M. Jr. (2003) The hedgehog signaling network. Am J Med Genet, 123A:5-28.> 
<Darnell J.E. Jr , Kerr I.M., Stark G.R. (1994) Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415–21>
<Jiang, J. & Hui, C.C. (2008) Hedgehog signaling in development and cancer. Dev. Cell 15, 801–812.>
<Hooper, J. E. & Scott, M. P. (2005) Communicating with Hedgehogs. Nature Rev. Mol. Cell Biol. 6, 306–317.>
<Rawlings J.S., Rosler K.M., Harrison D.A. (2004) The JAK/STAT signaling pathway. J Cell Sci 117 : 1281 –1283>
<Robbins D.J., Fei D.L., Riobo N.A. (2012) The hedgehog signal transduction network. Sci. Signal., p. re6>
<Nybakken, K. & Perrimon, N. (2002) Hedgehog signal transduction: recent findings. Curr. Opin. Genet. Dev. 12, 503–511>
<Schindler C & Darnell J.E. Jr . (1995) Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem. 64:621–51>
<Yu, H. & Jove, R. (2004) The STATs of cancer — new molecular targets come of age. Nature Rev. Cancer 4, 97–105.>
Developmentalbio (talk) 03:31, 20 March 2013 (UTC)
thread_title: References

message: Paracrine 27.63.179.136 (talk) 12:34, 15 June 2022 (UTC)
thread_title:  Paracrine