Talk:Angioedema

message: Refrenced in House MD Season 3 Episode 5 Fools for Love Ashton V. 05:44, Nov 14, 2006 (UTC)
:There is not much support for linking every disease to its occurrence in House MD. JFW | T@lk 15:28, 1 November 2007 (UTC)
thread_title:  House MD Reference 

message: It is still taught in med schools...  —Preceding unsigned comment added by 164.77.106.50 (talk) 01:36, 12 October 2007 (UTC)
replies: text: It is an incorrect term, and modern publications avoid its use for the obvious reasons that there is not meant to be a neurotic component to it at all. JFW | T@lk 15:28, 1 November 2007 (UTC)
thread_title:  How "outdated" is angioneurotic edema? 

message: Bork et al present a case series of HAE with normal C1INH:  JFW | T@lk 15:28, 1 November 2007 (UTC)
thread_title: HAE III

message: Annals of Allergy, Asthma and Immunology JFW | T@lk 13:55, 28 July 2008 (UTC)
replies: text: Better link: http://www.ncbi.nlm.nih.gov/pubmed?term=%22Ann+Allergy+Asthma+Immunol%22[Journal%3A__jrid8743]+AND+100[volume]+AND+1+Suppl+2[issue]+AND+angioedema&TransSchema=title JFW | T@lk 00:19, 9 December 2009 (UTC)
thread_title:  Whole journal issue 

message: We have no list of drugs reliably linked to angioedema. Only ACE inhibitors are mentioned.  is from 2001 but discusses this. More recent papers welcome. JFW | T@lk 06:29, 31 July 2008 (UTC)
thread_title:  Drugs 

message: If hereditary angioedema is due to deficiency of C1 esterase inhibitor, shouldn't that decrease the complement pathway?  C1 esterase breaks C1 down.  So an inhibitor should keep it from bring broken down.  And a deficiency of said inhibitor would allow it to be broken down (so many double-negatives).  Please explain the mechanism here a little more.
rhetoric (talk) 04:46, 16 September 2008 (UTC)
replies: text: If the article is unclear, please change it. JFW | T@lk 06:16, 16 September 2008 (UTC)
thread_title:  mechanism 

message: Why no mention of undiagnosable AE?  It's another type, in addition to acquired & hereditary.  Axe me how I know... ;-)  Each blood test contradicts the previous one; no known triggers (only biting my tongue); no response to ANY drug (antihistamines, NSAIDs, epinephrine...), and never airway intrusion (for me, go figure). Steve8394 (talk) 00:42, 18 January 2018 (UTC)
thread_title:  Idiopathic Angioedema 

message: Any fact, figure or helpful information that is true that you want to share to aide HAE cure research, write here. I believe angioedema can be controlled much better in the future.  —Preceding unsigned comment added by 67.170.146.158 (talk) 06:50, 27 October 2009 (UTC)
thread_title:  Researcher's interest 

message: has repeatedly reinserted a case report that discusses aspirin and ibuprofen as precipitants of angioedema. WP:MEDRS is very clear on such studies, and I have asked for a better source.  does seem to discuss NSAIDs but as I have no fulltext I wonder if aspirin is discussed too. Anyone have access to this paper? JFW | T@lk 00:09, 9 December 2009 (UTC)
replies: text: This paper discusses angioedema as a whole, not drugs as precipitants of HAE attacks. JFW | T@lk 00:14, 9 December 2009 (UTC)
replies: text: Not ibuprofen, Rofecoxib, with discussion of Celecoxib (still available). Doctors are still using the out-of-date studies that say aspirin-intolerance (inhibition of the COX-1 enzyme) does not portend a problem with selective COX-2 inhibitors. Most of the survey papers pre-date that indictment of them (the citation that was removed by the above user), which unfortunately looks as if it is "just a case study". This is important information for patients, notably for people afflicted with arthritis-like problems, whose angioedema might not be part of the basic affliction, but caused by the drugs prescribed to them. I found a dozen subsequent papers that discuss COX-2 inhibitors and angioedema, but I don't see any up-to-date complete surveys that would satisfy the above user. The time for survey papers has probably passed. Signing off. Nadiatalent (talk) 14:24, 9 December 2009 (UTC)

text: It is not Wikipedia's task to be a provider of "important information for patients". As I have tried to explain, WP:MEDRS uses a hierarchy of reference quality, and case reports are at the bottom of the food chain. Again, if you can identify a reliable secondary source that contains a list of medications known to precipitate HAE attacks, please let us know. JFW | T@lk 20:12, 9 December 2009 (UTC)
thread_title:  Aspirin and ibuprofen 

message: But this source talks about a dutch firms called pharming that is producing C1-INH in rabbits and milking them, then purifying the proteins to inject into patients. "   Now if you’re wondering if you are going to see gourmet bunny cheese showing up on your grocery store shelves soon, the answer is “no.” The milk is actually being gathered for a different purpose. The biotech industry is using the rabbits to produce a certain human protein that is then used to produce a—yes, you guessed it—drug.
Pharming, a biotech firm located in the Netherlands, has produced a warren of genetically engineered bunny rabbits that can produce up to 12 grams of a human protein called C1 inhibitor. The protein is then used to make an experimental drug that treats hereditary angioedema. People with this condition don’t produce enough C1 inhibitor, which can lead to painful swelling, cramps, and even possible death through suffocation." --216.67.85.20 (talk) 09:59, 2 February 2011 (UTC)
replies: text: So where are the clinical data? JFW | T@lk 12:52, 2 February 2011 (UTC)
thread_title:  I'm far too lazy to actually edit the article 

message: I think this article would be helpful to more users if there were a succinct summary in everyday terms that non-medical professionals could understand. Absolutely include the stuff about which mutations cause which forms of the hereditary stuff, but put it below a basic encyclopedia entry.  — Preceding unsigned comment added by Teodoro123 (talk • contribs) 23:00, 22 March 2013 (UTC)
replies: text: JFW | T@lk 09:47, 24 March 2013 (UTC)
thread_title:  Overall helpfulness of article 

message: Hello. My name is candice. Sunday evening I was admitted into the hospital for my face. My neck. My head. And the inside of my mouth being extremely swollen. They diagnosed me having ( Angioedema). The cause for mine was a blood pressure medication called ( Lisiniprill). I was released tuesday afternoon. Its now thursday morning and im swollen back up pretty good. Im feeling very nurvous. I took a 800 mg. IBUPROFEN and a 25mg. BENADRYL.  Around 4:30 am and i am still swollen up.( What else can i do to bring it down some??)  Cvoorhees7677 (talk) 11:27, 13 October 2016 (UTC)
replies: text: We don't give medical advice here. You should contact your own doctor. JFW | T@lk 22:09, 20 October 2016 (UTC)
thread_title:  Angioedema  

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thread_title:  External links modified