Talk:Depression

message: You can't get a reply?  I don't see a message from you to me anywhere.  I can't find a MoS reference to lists, but Help:List doesn't give blank lines inbetween list items as an option.  What is the purpose? Tedernst | talk 22:34, 28 December 2005 (UTC)
replies: text: I sent an email to you.  What is the accepted practice or what is most often done leave a message on article talk page, the person's talk page or email directly to them?  The purpose of blank lines are only to make it a little neater and easier to read.  The Help:List mentions blank lines in item two of the contents.  I don't understand why you didn't leave a reason for making the change?  Thanks, --Jim 22:52, 28 December 2005 (UTC)

text: (edit conflict) Email is seldom used. Use talk pages. I think the purpose of the blank lines is that they make the page easier to edit (in the edit window). However, the extra spaces make the page harder to intake for readers, since the entries are spaced out and the eye has to scan more area. I say leave out the spaces. Also, in long dab pages the spaces get rediculous, doubling the length of the page.--Commander Keane 23:23, 28 December 2005 (UTC)
replies: text: I took them out, sorry for confusion.  Thanks for the info and advice. --Jim 01:55, 29 December 2005 (UTC)
thread_title:  blank lines 

message: I see from the history that these changes are likely to be controversial, but this really isn't the page for more than a short sentence of explanation.  For example, the extent that brain chemistry changes are involved in clinical depression is not a simple subject, nor is the causality or otherwise of those changes.  All that is far too complex a subject to go into here, this should just give a very basic description of the meaning of the term.  Its not meant to inform as to the details of the condition - that's what the actual article is for.  It's just to help readers find which of the links they want to click to read more. -- sannse (talk) 20:40, 19 January 2006 (UTC)
replies: text: I'm working to solve this with more clear cross-referencing between the two articles and resolving ambiguous linking where possible, mostly according to whether described as an illness or treated as such.  There are also uses of the word that have been linked which don't come under any of the categories, so I've added depression (physiology), although if you look at the link from the Thesaurus page, it looks like we need depression (geometry) as well, or a wiktionary link.  --Cedderstk 09:22, 29 April 2006 (UTC)
thread_title: Changes to [[Depression (mood)]] and [[Clinical depression]]

message: Should be either labeled medicine or psychiatry.  Perferably medicine as most depression is dealt with either by family physicians, psychiatrists or emergency physicians. Psychiatry is the feild that has generated much of the terminology via the DSM4 Doc James (talk · contribs · email) 21:27, 4 November 2009 (UTC)
replies: text: I'd be ok with "psychiatry", but "medicine" seems a little too broad to me. If it's changed to medicine, the current "physiology" section would also fit under "medicine", and I think it makes more sense to separate the 2. Rreagan007 (talk) 15:23, 5 November 2009 (UTC)
thread_title: Naming of the catergory that includes depression

message: See also   Free PMC Article 
Allergy and Anxiety Symptoms Are Positively Correlated in Patients with Recurrent Mood Disorders Who Are Exposed to Seasonal Peaks of Aeroallergens (PubMed article) 
Changes in Severity of Allergy and Anxiety Symptoms Are Positively Correlated in Patients with Recurrent Mood Disorders Who Are Exposed to Seasonal Peaks of Aeroallergens  
 [PubMed]  Free PMC Article 
http://ukpmc.ac.uk/articlerender.cgi?tool=pubmed&pubmedid=19430577
:"We have recently found a preliminary association between symptoms of upper airway inflammation and depression (23) and between the seasonality of mood and self-reported mood sensitivity to high pollen counts (24). Additionally, in an animal model intended to examine the effects of allergic sensitization to tree pollen on depressive symptoms, we found significant anxiety-like behavior across trials in the sensitized animals following exposure to tree pollen (25). In individuals with allergic sensitization, when mast cell bound IgE antibody is crosslinked by specific allergens, an activating signal is transduced which results in mast cell degranulation and the release of inflammatory mediators and cytokines. Clinical investigation suggests that Th2-type lymphocytes are predominantly activated in allergic diseases. Th2 cells are characterized by their production of IL-4, IL-5, and IL-13. 
:Cytokines, administered in amounts below the threshold necessary to induce “sickness behaviors,” have been shown to induce anxiety, depression, and cognitive disturbances in healthy subjects (26). An increase in cytokine levels in the blood has been hypothesized as one potential catalyst for the decompensation of depression (27-29). Cytokine-treated patients may also experience an increase in depressive symptoms, including suicidal ideation and attempted suicide (30-33). Even a low dose of cytokine-promoting endotoxins such as lipopolysaccharides (LPS), can trigger depressive symptoms along with anxiety without bringing about other sickness behaviors (26). Certain cytokines released during LPS-induced inflammation are also released during the allergic response. For instance, mast cell degranulation releases TNF-α (34), the administration of which has been shown in animal models to be anxiogenic (33). We have seen that sensitization and subsequent exposure to tree pollen (25) and intranasal LPS administration (35) induce anxiety-like behaviors in sensitized rodents. Additionally, we have reported increased gene expression of cytokines involved with allergic inflammation (36) in the orbital cortex of suicide victims, where histopathological changes in suicide victims have been previously reported (14)." 
... 
:The relationship between anxiety and allergy scores became non-significant when we adjusted for depression scores for covariates. This suggests that the depression and anxiety scores are highly intercorrelated, with anxiety symptoms as a component of the depressive syndrome, or indicative of comorbidity between anxiety and depression. On the other hand, the relationship between depression scores and allergy symptom scores remained significant after adjustment for anxiety symptoms. These data suggest that the relationship between allergic disease and depression is a major phenomenon, and seemingly more robust than the one between allergic disease and measures of anxiety. However, our animal model data point towards a more consistent association between anxiety-like behaviors rather than depressive-like behaviors and with sensitization and exposure to tree pollen allergen (35,52). ...  —Preceding unsigned comment added by 66.167.61.217 (talk) 22:28, 23 May 2010 (UTC)
thread_title:   Changes in Severity of Allergy and Anxiety Symptoms Are Positively Correlated in Patients with Recurrent Mood Disorders Who Are Exposed to Seasonal Peaks of Aeroallergens 

message: https://www.infophysique.in/2020/06/all-you-should-know-about-depression.html  — Preceding unsigned comment added by Nipfactz (talk • contribs) 07:38, 25 June 2020 (UTC)
thread_title:  Semi-protected edit request on 25 June 2020