Talk:Indigestion

message: See edit 4th July. Are PPIs questionably effective for heartburn or is the evidence better than that?Mark 07:23, 5 July 2007 (UTC)
replies: text: Generally recognized as safe and effective per the sourced PPI page.  Edited accordingly (2.5 years later!). --Elvey (talk) 19:59, 5 November 2009 (UTC)
thread_title: start

message: Will it cause upset stomach? Will it cause some serious illness? Mrp8196 (talk) 15:14, 13 January 2014 (UTC)
thread_title:  [[Five-second rule|Eating food off floor after seconds]] 

message: Dyspepsia is a symptom rather than a disease. Cochrane defines it as heartburn and or epigastric pain. http://www.ncbi.nlm.nih.gov/pubmed/16235292  Doc James (talk · contribs · email) 02:59, 21 April 2010 (UTC)
replies: text: That seems like an overly limited definition. The medical dictionary has broader definition, which is "painful, difficult, or disturbed digestion, which may be accompanied by symptoms such as nausea and vomiting, heartburn, bloating, and stomach discomfort". Apparently there was even a 1986 conference meeting which studied the definition. I'm interested in seeing what this 2010 review has to say, but unfortunately don't have access.. think you could possibly send it to me? No pressure. II | (t - c) 21:55, 6 November 2010 (UTC)

text: Been reading a bit more about this and studies definitely include symptoms like nausea, early satiety or postprandial fullness, etc. in their definitions of dyspepsia. Treating Helicobacter pylori infection in primary care patients with uninvestigated dyspepsia: the Canadian adult dyspepsia empiric treatment—Helicobacter pylori positive (CADET-Hp) randomised controlled trial is an interesting article, and it mentions that "eradication of H pylori also relieved epigastric pain or discomfort and belching symptoms but not heartburn, regurgitation, bloating, nausea, early satiety, or postprandial fullness (data not shown)". II | (t - c) 01:08, 7 November 2010 (UTC)

text: There's a review of Japanese herbal treatments which show that several are pretty promising. Not many clinical trials though so I held off on putting it in the article, but very interesting. II | (t - c) 19:57, 3 January 2011 (UTC)
thread_title: symptom

message: Ingestion of PPI over a long period (some years) may cause in nerve diseases. The reason is, that vitamin B12 may not be uptaked/utilized enough because of lack of an intrinsic factor produced together with the stomac-acid. I myself got polyneuropathy (PNP) in feet (ingestion of Omeprazol over a period of > 7 years, 20 mg/d). Reducing the Omeprazol to 20 mg every 2...3...4...5 days (withdrawing) and infusion of B12 + Folic acid + B6 + B2 caused in very slow improvement (needs some years) of the feet-symptoms. My physicians (including neurologist) are convinced that the PPI´s are responsible for the PPN. Researching in internet one will finde some literature about these possible side effects of PPI´s.Anna Bolaine (talk) 06:57, 25 September 2013 (UTC)
thread_title: treatment

message: NEJM doi: 10.1056/NEJMra1501505 JFW | T@lk 21:56, 7 November 2015 (UTC)
thread_title:  Functional dyspepsia 

message: The signs and symptoms section doesn't have ... signs or symptoms.  — Preceding unsigned comment added by 99.240.51.235 (talk) 00:25, 24 January 2017 (UTC)
thread_title:  signs and symptoms 

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thread_title:  External links modified