Talk:Endometrial cancer

message: In premenopausal women who are not on birth control, the cause of endometrial cancer is overwhelmingly most likely to be lack of periods -- either significantly fewer periods than normal or completely absent periods. This causes a buildup of the uterine lining (endometrium) over time, and is known as endometrial hyperplasia. You first need to have endometrial hyperplasia to get endometrial cancer, yet most cases of endometrial hyperplasia will not become cancerous. Is this correct? 2601:98A:480:C080:289C:A68F:6403:3EFF (talk) 06:55, 29 April 2020 (UTC)

message: Most people prefer them over one line thus I would request that User:Headbomb revert his edits here  Doc James (talk · contribs · email) (if I write on your page reply on mine) 02:42, 28 July 2014 (UTC)
thread_title: Refs over one line or many

message: *The Sasa et al 2011 BMJ review says "Two investigations are mandatory in women with suspected endometrial cancer: a transvaginal ultrasound scan and an endometrial biopsy."  Article currently says "Transvaginal ultrasound to examine the endometrial thickness in women with postmenopausal bleeding is increasingly being used to aid in the diagnosis of endometrial cancer." which is rather different. If this a national difference between guidelines we should indicate so. 
**Yep, that appears to be a trans-Atlantic thing, since Hoffman et al. is an American textbook (as far as I can tell). I've clarified the difference in the text now. Keilana|Parlez ici 00:08, 20 August 2014 (UTC)
replies: text: Oops, sorry, mixed the 2 up, not for the first time. Your changes cover this point & the last point nicely. Wiki CRUK John (talk) 11:02, 21 August 2014 (UTC)
replies: text:  Hey, so I incorporated all the new information from the 2013 version, but there were two pieces of information included in the previous one that weren't in the latest version. Do you think they can stay, or should I remove them? Thanks, Keilana|Parlez ici 02:44, 25 August 2014 (UTC)

text:  Hi again, I incorporated all this information. It's not terribly well written yet but that will happen soon. :) Thanks for all these comments! Keilana|Parlez ici 01:53, 26 August 2014 (UTC)

text: More later, plus I hope soon by others here (these are just me). Wiki CRUK John (talk) 14:26, 19 August 2014 (UTC)
thread_title:  Belated points 

message: The "c blausen" needs to be removed from the image Doc James (talk · contribs · email) (if I write on your page reply on mine) 14:40, 24 August 2014 (UTC)
replies: text: Unfortunately, I have approximately 0 photoshop skills.... I could give it a shot but it would probably involve MS Paint... Keilana|Parlez ici 15:33, 24 August 2014 (UTC)
replies: text: My dad loves doing this sort of stuff. Let me see if I can convince him. Doc James (talk · contribs · email) (if I write on your page reply on mine) 21:31, 24 August 2014 (UTC)
replies: text: I managed to do it with paint. Doc James (talk · contribs · email) (if I write on your page reply on mine) 09:50, 25 August 2014 (UTC)
replies: text:  You are fantastic! Keilana|Parlez ici 13:56, 25 August 2014 (UTC)
thread_title: Lead image

message: I have had the feedback on this now, and have a marked-up print out. In general it was thought pretty good, and these are relatively minor points. I think I'll just make the smaller changes re wording etc myself now, but do say if there are any you have problems with. Then I'll list more complex things here.  Wiki CRUK John (talk) 15:54, 29 August 2014 (UTC)
replies: text: That's it. Wiki CRUK John (talk) 16:31, 29 August 2014 (UTC)
replies: text: Technically term is "adjunctive therapy". I have heard it referred to as "add on therapy" Doc James (talk · contribs · email) (if I write on your page reply on mine) 11:55, 30 August 2014 (UTC)
replies: text: Thank you SO MUCH for this review! I could not be more grateful. Keilana|Parlez ici 23:25, 31 August 2014 (UTC)
thread_title:  CRUK review 

message: I've set-up Endometrial cancer as a blurb for the Today's Featured Article requests process.
You can see it at Wikipedia:Today's featured article/requests/Endometrial cancer.
However, as I myself have nominated a bunch of other articles lately, I won't actually transclude it at Wikipedia:Today's featured article/requests.
If anyone else wishes to do so, they can follow the instructions at Wikipedia:Today's featured article/requests, and then a discussion will start as to the article's consideration for the Main Page.
Thank you,
— Cirt (talk) 01:50, 19 November 2014 (UTC)
thread_title:  Endometrial cancer for Today's Featured Article 

message: Have moved this here "Heart disease is the most common cause of death among endometrial cancer survivors . Obesity does not seem to play a role in prognosis of early stage endometrial cancer survivors ."
As it is supported by primary sources.
This secondary source disagrees that obesity does not affect prognosis in survivors. Doc James (talk · contribs · email) 23:33, 21 November 2014 (UTC)
replies: text: Hey, thanks for picking up on that. I don't remember adding that, but I also have only consumed one coffee this morning. Since the secondary source is from 2009 and the research is from 2012, I could put that sentence in #Research as something like "2012 research showed that heart disease was the most common cause of death among endometrial cancer survivors, though this relationship has not been confirmed." How does that sound? Keilana|Parlez ici 15:50, 22 November 2014 (UTC)
replies: text: Wasn't your edit. Have added back a bit of it. Feel free to remove that two though. Doc James (talk · contribs · email) 15:52, 22 November 2014 (UTC)
thread_title: Primary sources

message: I don't want to litter an FA with tags, but book sources need page numbers. This source is cited dozens of times, with no page nos.
* Hoffman, BL; Schorge, JO; Schaffer, JI; Halvorson, LM; Bradshaw, KD; Cunningham, FG, eds. (2012). "Endometrial Cancer". Williams Gynecology (2nd ed.). McGraw-Hill. .
::I mentioned this on the other page but I had been using an electronic copy that doesn't have page numbers; I just bought the hard copy and will be adding pages this afternoon (final paper due today, after that's done). Keilana|Parlez ici 16:17, 8 December 2014 (UTC)
replies: text: Just to clarify, I know this goes up in like 8 hours and I will have page numbers before then. Paper is due in an hour and a half and I need to go finish that. I'll check back then. Keilana|Parlez ici 16:30, 8 December 2014 (UTC)
replies: text:   I am not suggesting you must do it before TFA (just concerned generally that things like this are getting though FAC).  Please focus on your paper first!  SandyGeorgia (Talk) 17:24, 8 December 2014 (UTC)
replies: text:  Paper is done (8 whole minutes before the deadline!) and no more exams today so I do have time to get this finished. :) Keilana|Parlez ici 18:12, 8 December 2014 (UTC)

text: It's got a date (December 2011) and I hadn't realized it had a PMID. Should be better now. Keilana|Parlez ici 16:17, 8 December 2014 (UTC)
thread_title:  Sourcing 

message: * In the United States, white women have a higher survival rate than Black women, who tend to develop more aggressive forms of the disease.
Not sure why white is lower case, Black upper, and should the term African American be used instead?  SandyGeorgia (Talk) 20:02, 6 December 2014 (UTC)
replies: text: White was a typo, and since the source said "Black", I'm hesitant to assume African-American women only; that could include Caribbean-American women etc. They didn't specify what constituted "Black". Keilana|Parlez ici 16:19, 8 December 2014 (UTC)
thread_title:  Prose 

message: The lead says:
* Whereas taking estrogen alone increases the risk of endometrial cancer, taking both estrogen and progesterone in combination, as in most birth control pills, decreases the risk.
I cannot find that in the first citation given, and the second is not an online source.
The body of the article says:
* Progestin is present in the combined oral contraceptive pill and the hormonal intrauterine device (IUD). Combined oral contraceptives reduce risk more the longer they are taken: by 56% after 4 years, 67% after 8 years, and 72% after 12 years. This risk reduction continues for at least 15 years after contraceptive use has been stopped.
And the sources given for this section are different than those used in the lead.  One says:
* Risk factors include postmenopausal estrogen therapy,  ... and nothing about 15 years, and nothing about combined vs. solo therapy, and nothing with those risk numbers at all.  (That is, the text doesn't seem to be cited, doesn't seem to agree with the lead).
This stands out to me because combo therapy is controversial; some ob/gyns and endocrinologists give progesterone and estrogen separately.  This needs to be sorted.  SandyGeorgia (Talk) 16:00, 8 December 2014 (UTC)
replies: text: So in the NCI PDQ summary, it says this: "Based on solid evidence, at least 1 year’s use of oral contraceptives containing estrogen and progesterone decreases endometrial cancer risk, proportionate to duration of use. This benefit lasts at least 15 years after cessation.[1,2] Magnitude of Effect: Use of oral contraceptives for 4 years reduced risk by 56%, 8 years by 67%, and 12 years by 72%.". That's where the 15 years is coming from and it seems to be cited to the correct page in the article. And since it says "containing estrogen and progesterone", I think that clarifies the combined therapy. Combo therapy is not really controversial, you can give separate estrogen and progesterone pills or have them in the same pill, what matters for endometrial cancer is whether the estrogen therapy is unopposed by progesterone or not. I think we covered the "most birth control pills" thing elsewhere. Keilana|Parlez ici 16:26, 8 December 2014 (UTC)
replies: text:  OK, that info clears it up, but ... I'm not getting that text at all from the link given in the citation.  I have now found it, and it looks like you meant to link to page 2 ??    SandyGeorgia (Talk) 17:31, 8 December 2014 (UTC)
replies: text:  Yep, definitely meant to link it to page 2. Should be sorted now. Keilana|Parlez ici 18:10, 8 December 2014 (UTC)
thread_title:  Birth control clarification 

message: Probably best taken up at WT:MED, but I don't know why the FA menstrual cycle is linked nowhere in this article, relative to the c-class menstruation, which is linked.  SandyGeorgia (Talk) 18:03, 8 December 2014 (UTC)
replies: text: Never mind, found it and fixed the link to avoid redirect.  (There is a toolbox on FACs to check for redirects.)  SandyGeorgia (Talk) 18:17, 8 December 2014 (UTC)
replies: text: Could you show me that tool? I'm not familiar with it and it sounds super useful. Keilana|Parlez ici 18:43, 8 December 2014 (UTC)
replies: text:  I've installed them at the top of this page (you can use them on any article), but I suspect that all of the tools in the box aren't working as they used to.  SandyGeorgia (Talk) 19:08, 8 December 2014 (UTC)
replies: text:  That's nifty! It's not showing any more weird redirects, just what redirects to this article. Thank you! Keilana|Parlez ici 19:23, 8 December 2014 (UTC)
thread_title:  Another (related) matter 

message: This is at endometriosis:
* Despite similarities in their name and location, endometriosis bears no relationship to endometrial cancer.
Is it worthy of mention here?  SandyGeorgia (Talk) 19:55, 6 December 2014 (UTC)
replies: text: I think this is adequately addressed with the section on endometrial hyperplasia but I wouldn't be opposed to a hatnote or something. Keilana|Parlez ici 16:02, 8 December 2014 (UTC)
thread_title:  Endometriosis 

message: I was somewhat nauseated by the appearance of this bloody medical photograph, which appears as the first image on the main page today. Should we display a different image from this article on the Main Page? Jarble (talk) 06:17, 9 December 2014 (UTC)
replies: text: I would choose a micrograph. Doc James (talk · contribs · email) 06:43, 9 December 2014 (UTC)
replies: text: I don't really see an issue with the current picture. --Guerillero | My Talk 07:02, 9 December 2014 (UTC)
replies: text: Accuracy is great, but I agree - maybe a little too real  — Preceding unsigned comment added by 74.88.35.154 (talk) 08:07, 9 December 2014 (UTC)
replies: text: I believe in drawing people to an article, not driving them away with disturbing imagery. I'm a cancer survivor so I know how ugly this disease can be but many people are going to be unsettled by the bloody image and it seems a poor choice.Rob Banzai (talk) 19:11, 9 December 2014 (UTC)

text: Yes we should have done for the main age, and probably should still change it. Apart from anything else, like most such images it doesn't really convey anything much to those not medically trained.  I don't believe in micrographs as lead pics either, for the same reason; these only convey anything to pathologists etc, and we rarely explain them at all. In a case like this a diagram showing where the endometrium is (not exactly common knowledge) is usually the best choice. But I have some potential COI, as many of such images are CRUK releases, though far from all. Wiki CRUK John (talk) 14:05, 10 December 2014 (UTC)
replies: text: Oh, I forgot we have a very decent Blausen diagram as the actual lead pic in the article. It was a mistake not to use that or similar on the TFA blub. Wiki CRUK John (talk) 14:11, 10 December 2014 (UTC)
thread_title:  Should we choose a less disturbing image for the Main Page? 

message: The new NICE guideline for suspected cancer (http://www.nice.org.uk/guidance/NG12, page 160-166 of the full guideline) discusses warning signs for endometrial cancer and when to perform gynaecological ultrasound. In women over 55 USS is suggested in those with unexplained vaginal discharge (when presenting de novo or if associated with thrombocytosis or hyperglycaemia) or those with haematuria (associated with either anaemia or thrombocytosis or hyperglycaemia). This is largely based on doi:10.3399/bjgp13X671632 which itself is a primary source. Worth discussing the relevance of these features? JFW | T@lk 14:03, 24 December 2015 (UTC)
thread_title:  Thombocytosis and hyperglycaemia 

message: doi:10.1016/S0140-6736(15)00130-0 Might be useful to match this with the current content. JFW | T@lk 13:10, 11 March 2016 (UTC)
thread_title:  Lancet seminar 

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thread_title:  External links modified