Talk:Anticholinergic

message: Effects include both bradycardia and tachycardia? Aren't they mutually exclusive?  —Preceding unsigned comment added by 24.25.232.153 (talk) 16:45, 28 November 2009 (UTC)
replies: text: Curare and atropine are antagonists, not agonists. Aenar 10:36, 22 October 2007 (UTC)
thread_title: Comments

message: I didn't want to add this myself in case it's too crude, but my pharmacology professor taught us this: "Can't see, can't pee, can't spit, can't s***, and tachycardia."  That describes the symptoms of blurred vision, decreased urinary output, dry mouth, constipation, and of course a fast heartbeat. Kat, Queen of Typos 01:08, 7 June 2006 (UTC)
thread_title:  Another mnemonic 

message: Is anticholergenic something different or just a gross misspelling of Anticholinergic? A google search for the former returns some results but all seem like they really want the latter? Can anyone that knows better shed some light? - Taxman Talk 21:35, August 30, 2005 (UTC)
1. In reply to your question, I should assume that the two are different because I wasnt aware that Benadryl (Diphenhydramine) was an Anticholinergic drug. The reason I involve Benadryl is because the first result of a google search on Cholergenic returns http://www.dr-bob.org/babble/20031021/msgs/271639.html. 
- Xer0X 12:35, 7 November 2005 (UTC)
replies: text: I agree with 2.  And I was wondering why antihistamines (H1 receptor antagonists) aren't listed in this article.  But I'm not sure if all of them are anticholinergics, or only some.  Diphenhydramine and dimenhydrinate are, at least, but the antihistamine article doesn't seem to be very clear on this. --Galaxiaad 09:20, 26 February 2007 (UTC)
thread_title: Question

message: Should this article be merged with deliriant?  --Thoric 16:25, 5 May 2006 (UTC)
thread_title:  Merge? 

message: Under "Effects" there is a sentence which says "Exceptions to the above include scopolamine, orphenadrine, dicycloverine/dicyclomine and first-generation antihistamines with central nervous system penetration.". I think "the above" refers to the list of conditions anticholinergics are used to treat, but it's not entirely clear...  —Preceding unsigned comment added by Technome (talk • contribs) 22:16, 14 July 2010 (UTC)
thread_title:  Ambiguous sentence 

message: The first sentence stating gabapentin as a cholinergic antagonist is completely and utterly wrong.  I could not even bring myself to continue reading the rest of the article.  Gabapentin is a Ca++ channel antagonist (alpha2delta subunit of Ca++ channel to be exact) and has absolutely nothing to do with an acetylcholine receptor.  —Preceding unsigned comment added by 216.8.121.1 (talk) 13:53, 9 September 2010 (UTC)
thread_title:  This article needs serious work. 

message: "Anticholinergic drugs are usually considered the least enjoyable by experienced recreational drug users,[citation needed] possibly due to the lack of euphoria caused by them. In terms of recreational use, anticholinergics are generally classified as deleriants. Because most users do not enjoy the experience, they do not use it again, or do so very rarely."
The fact that cholinergic antagonists are usually considered the least enjoyable by experienced recreational drug users is a well-known fact; however, I don't know how to cite any sources to support this, given that all of them either reference Wikipedia (this page), or they are posted on forums, esp. in the form of 'experience reports.'  — Preceding unsigned comment added by SlimNm (talk • contribs) 02:05, 23 December 2010 (UTC)
thread_title:  Effects 

message: There's quite a big News story about anticholinergics and their effects broken today: http://www.bbc.co.uk/news/health-13880553 (based on a study by the UEA) - VJ (talk) 08:33, 24 June 2011 (UTC)
thread_title: News Story

message: Is it possible to add a reference to this article? If so, how?  — Preceding unsigned comment added by 67.173.129.194 (talk) 05:33, 2 April 2012 (UTC)
thread_title:  There is no citation 

message: Possibly worthy of note:  Anticholinergics are sometimes used in the treatment of Parkinson's Disease and Parkinsonism.  It has something to do with the balance of dopamine and acetylcholine (spelling?), and its use reduces tremor symptoms.  This is way out of my area of study, but I'm noting it in the hopes that it can be referenced and added eventually.67.167.106.3 (talk) 18:13, 1 May 2012 (UTC)
thread_title:  Medical uses 

message: In section Acute Anticholinergic Syndrome, it references shaking as a symptom.  Would that be more correct as tremor?67.167.106.3 (talk) 09:18, 29 May 2012 (UTC)
thread_title:  Should shaking be tremor? 

message: Under Acute Anticholinergic Syndrome/Remedies the article states " Previously, reversible cholinergic agents such as physostigmine were used but this was found to increase the risk of cardiac toxicity (no reference; unable to verify in PubMed literature search 12/31/11)[citation needed]" A Google Scholar search produces a link to THA—A Review of the Literature and Its Use in Treatment of Five Overdose Patients, 1980, Vol. 16, No. 3 , Pages 269-281 (doi:10.3109/15563658008989949), William K. Summers, Kenneth R. Kaufman, Frank Altman and John M. Fischer (http://informahealthcare.com/doi/abs/10.3109/15563658008989949). The brief excerpt on Google includes the blurb "Cardiac toxicity has been noted in the use of physostigmine and other anticholinesterases [ 12, 15, 211. In contrast, THA, despite potent anticholinesterase activity, is not reported to have serious cardiac toxicity," but I have no access to any better abstract, full article, or even just the review's citations. Maybe someone else with journal access can track down these sources and confirm the factoid.  — Preceding unsigned comment added by 107.3.42.169 (talk) 17:02, 26 August 2012 (UTC)
thread_title:  "Cardiac toxicity" cite 

message: The section 'medical and recreational uses' says "Exceptions to the above include [list of drugs]."
It's not clear which bit of 'the above' is meant. CarrieVS (talk) 22:11, 12 May 2013 (UTC)
thread_title:  Exceptions to what? 

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thread_title:  External links modified 

message: https://edition.cnn.com/2019/06/24/health/dementia-risk-drug-study/index.html indicates there is an increased risk of dementia in individuals takingcertain types of these drugs. Kdammers (talk) 02:14, 25 June 2019 (UTC)
thread_title:  dementia 

message: These pages are almost identical, although "Cholinergic blocking drug" is more detailed. Both articles list medical uses, side effects, intoxication (and treatment of intoxication), and both articles use the same basic classification system (antimuscarinic / antinicotinic). Am I missing something here or could these pages be merged? Jack 46189 (talk) 10:18, 1 February 2023 (UTC)
thread_title:  Why are "anticholinergic" and "cholinergic blocking drug" two separate pages?