lflage/wiki-talks huggingface dataset:
Talk:Pramlintide

message: I just had a question about "pramlintide aids in the absorption of glucose" which does not seem quite correct as ultimately it reduces post-prandial glucose.
Heli dr (talk) 18:16, 5 January 2011 (UTC)
replies: text: I share your concerns: as you said it's a PPHG reducers. I mean, it depends on how you interpret the "aids": in a certain way it aids in the absorption of glucose, not because it increases the amount of glucose absorbed but because it produces a smoother curve in the glycaemia (as opposed to a sharper peak) by decreasing the gastric emptying rate (and inhibiting the glucagon secretion by alpha cells). What I would like to point out is that, in the same sentence, it sounds weird to my non-english ears to read "By augmenting endogenous amylin". While pramlintide is, yes, an amylin analogue it has with a different amminoacidic sequence and different properties (above other it has a longer half-life and doesn't give aggregation like amylin) than amylin. In other words to my eyes it can't be just considered to be like the endogenous amylin tout court. I see here the same difference between the first human recombinant insulin and the rapid-acting insulin analogues LisPro Asparte etc, just to remain in topic. -- Radio89 (talk) 18:35, 19 February 2012 (UTC)
replies: text:  Maybe my edits help a little bit? AvB (talk) 01:52, 8 August 2017 (UTC)
thread_title: aids in the absorption of glucose ?

message: "Symlin also prompts a marker for Alzheimer’s – amyloid beta – to travel from the brain to the blood."  - Rod57 (talk) 17:12, 21 March 2017 (UTC)
thread_title:  Other effects
Talk:Pranlukast

message: The structure of the compound is wrong.  — Preceding unsigned comment added by 217.91.13.143 (talk) 09:31, 4 February 2013 (UTC)
replies: text: Indeed, the chemical structure image and the IUPAC name given were inconsistent. Looking at the links in the infobox to various databases, it appears as if the image is correct so I have updated the IUPAC name.  -- Ed (Edgar181) 12:33, 22 March 2016 (UTC)
thread_title: Structure/name inconsistency
Talk:Selective abortion and infanticide

message: Problem solved. The rest of the text is visible now. —The preceding unsigned comment was added by Jfraatz (talk • contribs) 00:10, 2 March 2007 (UTC)
thread_title:  Problem solved.   

message: I boldly merged Prenatal discrimination and Sex-selective abortion and infanticide into this new article, as per Wikipedia:Articles for deletion/Prenatal discrimination. This article needs a lot of work as it's absolutely filled with unsourced claims, POV statements and original research. I took the liberty of adding tags at the top of the page and inserting various in-line tags as well. Hopefully editors can fill in the blanks with reliable sourcing. -- Scientizzle 03:58, 8 March 2007 (UTC)
thread_title: Merge complete

message: Because the article has been tagged for insufficent citations, we need to hire citation hunters, getting the article in accordance to accepted Wikipedia standards. Decimus Tedius Regio Zanarukando 22:48, 10 March 2007 (UTC)
thread_title:  Citation search
Talk:M. Osman Siddique

message: One editor claimed that his son works for the UNDP, and I did find a link for an Omar Siddique at a UNDP site, at
http://www.undprcc.lk/About_Us/Staff_Directory.asp?W=M-P
:Still there is no indication that this is his son. Could someone find a clear source that this is his son?
::--Wowaconia 00:05, 2 March 2007 (UTC)
thread_title: Does his son work for the UN?
Talk:Will You Please Be Quiet, Please?

message: Why does the search term "Night school" redirect here?  —Preceding unsigned comment added by 67.182.86.31 (talk) 04:11, 7 January 2008 (UTC)
replies: text: Seems 'Night school' now has a redirect page, so this looks to have been cleared up. --Chronotopian (talk) 18:00, 11 September 2012 (UTC)
thread_title:  Night school? 

message: I've been writing brief plot summaries for each of the stories, to even out the inconsistency from before - a couple of stories had paragraph summaries, and the others were only a line long. 
However, it looks now like with 22 stories, this is going to make the article quite long. The question is - is this too long? If so, should plot summaries be on this page at all? The guidelines on fiction are not specifically clear on this, with regards to short fiction. One solution that I'd propose is to simply list the stories here and use this page for critical reception, themes, etc of the collection overall. Then I can produce individual pages for notable stories that have good criticism. 'Neighbors' already has a page, but there will be a few others.  Thoughts? --Chronotopian (talk) 15:20, 14 September 2012 (UTC)
thread_title:  Plot Summaries
Talk:Stafford, Connecticut

message: This merge request of Stafford Springs, Connecticut doesn't make sense to me.  I will delete it in a few days and clean up the Stafford Springs article if I don't hear any objection. --Selket Talk 00:07, 2 March 2007 (UTC)
replies: text: Why doesn't it make sense? As of about 15 years ago the towns are all merged. --08:38, 2 March 2007 (UTC)
replies: text: I have no opinion, but I do hope that the Stafford Springs article gets cleaned up. I also hope someone will write an article about the notable racetrack in the area. Royalbroil T : C 04:25, 3 March 2007 (UTC)
thread_title: Merge

message: There is a move discussion in progress on Talk:Stafford Hollow, Connecticut which affects this page. Please participate on that page and not in this talk page section. Thank you.  —RM bot 16:30, 28 January 2010 (UTC)
thread_title: Move discussion in progress
Talk:Procarbazine

message: "It is also highly carcinogenic - patients have a 5-10% risk of developing acute leukemia,"
What? Either this statement is extremely lacking in context, or there is no way this drug could ever be used on humans. If the later is true, the entire article needs a re-write because it's written in the current tense.
Maury (talk) 18:23, 3 June 2008 (UTC)
replies: text: It does seem dubious, and it is an unreferenced statement, so I have removed it.  -- Ed (Edgar181) 19:39, 24 August 2010 (UTC)
thread_title:  Huh? 

message: Does it really cost $50 per capsule in the US? It's £3.80 trade in the UK, which is about $5, not $50. --81.154.227.79 (talk) 18:04, 24 August 2010 (UTC)
replies: text: Drug pricing can be highly variable, so I have removed the statement.  It's not all that relevant to an encyclopedia article anyway.  -- Ed (Edgar181) 19:39, 24 August 2010 (UTC)
thread_title:  Cost 

message: doc james I know the WHO ref says "depression" but i think they meant "lethargy".  have not found any other ref that says that. Jytdog (talk) 00:26, 20 December 2016 (UTC)
replies: text: Hey User:Jytdog here it also says "possible mental depression"  Doc James (talk · contribs · email) 03:16, 21 December 2016 (UTC)
replies: text: right which isn't depression (mood) or major depressive disorder which is what plain old "depression" will lead folks to think...  what the heck is "mental depression"?  Jytdog (talk) 03:25, 21 December 2016 (UTC)
replies: text: That is depression (mood) or major depressive disorder. They state "mental depression" to separate it from having depressed strength or energy. Doc James (talk · contribs · email) 04:47, 21 December 2016 (UTC)
thread_title:  "depression" 

message: Procarbazine is also used as chemotherapy for some animals. The article only speaks of humans. Worth an addition? Syneil (talk) 09:15, 16 February 2017 (UTC)
thread_title:  Veterinary use 

message: The MOA for Procarbazine is still poorly understood; but there does seem to be a better understanding now associated with methylation etc. I don't want to make an official edit of the article page; only because I don't have the PubMed article I read on this readily available. But I am on the UpToDate article and it also confirms the same idea:
"Procarbazine inhibits DNA, RNA, and protein synthesis by inhibiting transmethylation of methionine into transfer RNA; may also damage DNA directly through alkylation."
The Link is here for anyone with access to read: UpToDate. ---- Paul K. | MechE | MSY-2 | Chemist | Let's talk 15:22, 7 November 2019 (UTC)
thread_title:  MOA: Procarbazine
Talk:Proguanil

message: Student editors: Lois.chung, Floal1, Collierpharmd, Hwhittemore13 will be making the following improvements and edits:
Lois.chung will be addressing the "Mechanism" section. Elaborating on mechanism details.
Floal1 will be addressing the "Precautions" section. Adding information on liver precautions.
Collierpharmd will be addressing the "Introduction" section. Will be adding a bit of history, and moving other information to appropriate sections.
Hwhittemore13 will be addressing the "Medical uses" section. Elaborating on populations and uses.
Collierpharmd (talk) 19:11, 4 November 2016 (UTC)
thread_title:  Improvements to Proguanil article 

message: Is there any evidence of plagiarism or copyright violation?
We found no apparent evidence of plagiarism or copyright violation. Hjkim1988 (talk) 00:17, 15 November 2016 (UTC)
thread_title:  Peer review: STUDENT 4 

message: Does the draft submission reflect a neutral point of view? If not, specify…
'''
Yes, throughout the article they seemed to keep a neutral point of view. 
Nishp14 (talk) 00:18, 15 November 2016 (UTC)
thread_title:  Peer Review- Student 1 

message: Precautions section: Recommending monitoring of certain labs may not be appropriate for Wikipedia
Medical uses section: Perhaps there can be a citation on the pricing for mefloquine vs. Proguanil
Piadizon (talk) 00:20, 15 November 2016 (UTC)
thread_title:  Peer review: Student 3 

message: Question – Are the points included verifiable with cited secondary sources that are freely accessible? If not, specify…
Answer- Not all the points that were included were verifiable with cited secondary sources that are freely accessible. 
The following citations were not accessible at all: 
[2] 
[4]
[9]
[19] 
The following were not from secondary sources:
[1]: prescribing info
[5]: primary lit
[8]: primary lit
[14]: primary lit
[17]: primary lit
[18]: primary lit
MitraFazel (talk) 00:40, 15 November 2016 (UTC)
thread_title:  Student 2
Talk:Limax cinereoniger

message: Really strange distribution range. Surely it is in other places too?  — Preceding unsigned comment added by 213.33.10.108 (talk) 20:50, 12 July 2013 (UTC)
Talk:Protriptyline

message: "Unique among the TCAs, protriptyline tends to be energizing instead of sedating, and it is sometimes used in narcolepsy to achieve a wakefulness-promoting effect."
How is it different from desipramine and nortriptyline, since all 3 have similar high sert/net affinities. Nuklear (talk) 07:52, 5 July 2009 (UTC)
thread_title: Untitled
Talk:Conulariids

message: This article needs to define the term in the first sentence. It does not even say what it is. 76.185.183.215 00:21, 2 March 2007 (UTC)

message: These two pages should be combined and one eliminated.  I don't know how to do it.  See Conulariida.  Wilson44691 (talk) 01:11, 24 July 2008 (UTC)
thread_title:  Another page called "[[Conulariida]]"
Talk:Quazepam

message: The last three sentences in the introduction need to go because they are personal observations. (I tend to get rudely rebuffed when I attempt to improve articles by bringing them up to scratch, even in the most minor ways, so I've lost the balls to edit the article myself. Incidentally, this may be why so few women edit Wikipedia--we get shouted at for being correct, and get sick of it fast.) Hipvicar (talk) 03:15, 8 October 2014 (UTC)
Talk:Quinidine

message: take WHO-recommendations on Plasmodium falciparum malaria: ACT are first line therapy, forget ato/proguanil --> check this please  —Preceding unsigned comment added by 80.78.17.11 (talk) 11:57, 3 May 2010 (UTC)
thread_title: Untitled

message: The history section talks most about quinine and then jumps to quinidine. When were they separated (and how) ? - Rod57 (talk) 22:34, 10 September 2012 (UTC)
thread_title:  when was quinidine distinguished and separated from quinine 

message: Not mentioned or explained in article. 86.159.197.174 (talk) 04:00, 22 August 2014 (UTC)
thread_title:  Why does "conquinine" redirect here? 

message: There is a "do not confuse" flag in both quinine and quinidine, but they appear (in the chemical formula and skeletal diagram, as well as the listed characteistics like molecular weight) to be identical. Are they merely two different medical uses of the same compound, or are they chemically different in some (unspecified in the article or data page) way?
:Riventree (talk) 12:25, 10 April 2017 (UTC)
thread_title:  vs quinine
Talk:Hollin Hall (Virginia)

message: There is no reason why a congration should be covered in a separate article to their church building. Most pertinent is the the congregation itself does not pass the notability requirements for organisations. I suggest combining the two leaving a redirect. — Frayæ (Talk/Spjall) 19:03, 13 July 2018 (UTC)
replies: text: I think having separate articles for a congregation and its building is fine and somewhat common. Which notability requirements do you think are unmet? I added some incoming links to this article just now. --MZMcBride (talk) 19:27, 13 July 2018 (UTC)
replies: text:  Specifically Wikipedia:Notability (organizations and companies). Multiple independent sources. Right now there are two citations to connectionnewspapers.com, which is good, but not very strong, and much below what would be asked for at the deletion venue. Neither article is likely to grow much, and both are small. It's not a requirement though. — Frayæ (Talk/Spjall) 19:35, 13 July 2018 (UTC)
replies: text:  Oppose. I have added a number of references from The Washington Post dating back to the 1970s. (As a minor point of clarification, Hollin Hall is just one of the buildings and not the primary church building.) I believe the added references help establish notability. Skynxnex (talk) 20:47, 24 July 2018 (UTC)
thread_title:  Proposed merge with [[Mount Vernon Unitarian Church]]
Talk:International Typeface Corporation

message: The link for Aaron Burns goes to a bio of a soccer player, can someone please fix this.
: Another user unlinked the name. Ringbang (talk) 01:39, 23 August 2012 (UTC)
thread_title: Aaron Burns

message: The history section sounds like a rather subjective and negative viewpoint. ITC was a well respected design company at a time when the Madison Avenue advertising world was significant. As trends will do, ITC fonts reflected the times, coming out of the late 60 with Peter Max and Warhol. (GreenEconomy (talk) 13:34, 4 July 2014 (UTC)
thread_title: History
Talk:Bielzia

message: :The following is a closed discussion of a requested move. Please do not modify it. Subsequent comments should be made in a new section on the talk page. Editors desiring to contest the closing decision should consider a move review after discussing it on the closer's talk page. No further edits should be made to this discussion. 
The result of the move request was: Moved to Bielzia.   signed, Iflaq (talk) 12:56, 8 November 2021 (UTC)
replies: text: Bielzia coerulans →  – Monotypic genus Estopedist1 (talk) 20:24, 30 October 2021 (UTC)

text: Support per nom. YorkshireExpat (talk) 21:40, 4 November 2021 (UTC)
thread_title:  Requested move 30 October 2021
Talk:Ramipril

message: If you have medical knowledge yourself, Do not fall pray to first doctor (Please be careful in third countries). Please ask as many questions you till you are satisfied.  It is possible to remember every thing,or one forget some important point. For example, how old she is pregnant. Do not forget to get through WIKIPEDIA. —Preceding unsigned comment added by  (talk • contribs) 
* Ummm ... what? Can you please rewrite this entry for clarity? I have no idea what your statement is supposed to mean. Thanks, Hu Gadarn 14:55, 7 August 2007 (UTC)
thread_title:  Carsiovascl 

message: Ummm ... what?  Is it possible to use another word/ phrase here or if not at least a hyperlink?  I'm on this drug and have never heard of "contraindications" before. The word has no meaning to me. Thanks, Hu Gadarn 14:55, 7 August 2007 (UTC)
replies: text: "Indications" are the reasons you'd take a drug - high blood pressure in this case. "Contra-indications" are the reasons you'd avoid taking it - pregnancy being a common contraindication for many drugs. The usage is standard. Alec.brady 08:31, 25 October 2007 (UTC)
thread_title:  "Contraindications"? 

message: ACE inhibitor says "Because ramipril has been shown to reduce mortality rates even among patient groups not suffering from hypertension, there is widespread belief that ramipril's benefits may extend beyond those of the general abilities it holds in common with other members of the ACE inhibitor class."  If we can source/verify that, perhaps it can go in this article. Rod57 (talk) 03:25, 18 December 2008 (UTC)
thread_title:  Other benefits 

message: The article states half life is 2-4 hours.Actually that's only for the first stage oft distribution, effective (?) half life is much longer, see http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/CPS-%20%28General%20Monographs-%20A%29/ALTACE.html  — Preceding unsigned comment added by 37.120.9.253 (talk) 08:28, 11 March 2015 (UTC)
thread_title:  Half life ist wrong 

message: Article report wrong market name in Italy, right is Triatec by Sanofi.
IlGrigioPellegrino (talk) 08:12, 1 November 2015 (UTC)
thread_title:  Market Name 

message: — Assignment last updated by JustinxLane (talk) 19:04, 2 June 2023 (UTC)
thread_title: Wiki Education assignment: PHMD 2040 Service - Learning Spring 2023
Talk:Rapacuronium bromide

message: The CAS Number is for the bromide but the structure done does not have the counterion--ChemSpiderMan (talk) 04:05, 20 December 2007 (UTC)
replies: text: Counterion added. I'll update the formula and molecular mass soon. Fvasconcellos (t·c) 13:21, 20 December 2007 (UTC)
thread_title: Structure
Talk:Samuel Krauss

message: Oops — I stubbed this out but didn't come back to it. He was a notable scholar of linguistics. I'll add more info soon. -- Kendrick7talk 00:38, 2 March 2007 (UTC)
replies: text: OK that should do it. -- Kendrick7talk 01:27, 2 March 2007 (UTC)
thread_title: Hang on
Talk:Vunivalu of Bau

message: shouldn't the correct title read Turaga na Tui Kaba Na Vunivalu?
MB 00:41, 2 March 2007 (UTC)
thread_title: query

message: The position has now been filled since 10/03/23 - https://islandsbusiness.com/latest-magazine-articles/chief-cakobau/ 92.238.148.4 (talk) 17:24, 10 June 2023 (UTC)
thread_title:  New Vunivalu installed
Talk:B67 (New York City bus)

message: My fault for not doing this earlier, but I want to propose merging the B67 and B69 pages. They share around half of their route together, and have interlined frequencies and share a timetable with each other, and considering that other route groups that share this share a page, I was thinking the same could happen for the B67 and B69. Ex696 (talk) 01:46, 28 January 2024 (UTC)
thread_title:  Merging the B67 and B69 pages
Talk:Tagawa Matsu

message: She was also the mother of 田川七左衛門. Anyone know how to romanize it? Hanfresco 00:50, 2 March 2007 (UTC)
replies: text: added to the article using this romanization ^^ ty~. Hanfresco 09:37, 4 March 2007 (UTC)
thread_title: Untitled

message: What's the source on her personal name?  Every source I've looked at says that it has been lost to posterity. Limeatine (talk) 02:17, 20 January 2009 (UTC)
replies: text: "Lost to posterity" is a little grandiose. It is more likely she had never had an official, recorded given name. In the Japanese medieval period, and at least into the early Edo period, women were not granted surnames (neither were commoners), and though I haven't read of an official policy, from my own studies of Japanese women in history, it does not appear that they had officially recorded personal names, either. At least, not at birth, though if she became a nun (for example) the convent she entered might record her new Buddhist name. In some cases, women in history were notable enough that their names appeared frequently in letters or court records; in other cases, a personal name or nickname might be recorded at the Buddhist temple after death, along with the Buddhist posthumous name. See examples such as Murasaki Shikibu, Komatsuhime, Lady Saigo. Boneyard90 (talk) 14:31, 3 August 2011 (UTC)
thread_title: Name
Talk:Caroline Spurgeon

message: Can someone improve on the statement at the bottom of the article (which reads more like some leering innuendo than a factual statement? Maybe Spurgeon was a lesbian. But right now the statement "Spurgeon, Virginia Gildersleeve, Meta Tuke, Lilian Clapham and others enjoyed interweaving intimate relationships and shared their summers" sounds more of accusing a trio of women who were friends and shared vacations of doing (nudge nudge, wink wink) something more than that. And it is badly sourced (one external link that is more chatty than factual?) That edit honestly borders on vandalism. -- llywrch 22:06, 15 July 2007 (UTC)
thread_title: Untitled
Talk:Northern moon snail

message: Hi guys, I wanted to say a couple of things.
1. I think this article should be about Moon Snails in general -- in other words it should be about the family Naticidae, and there should be a separate article about the Northern Moonsnail, Lunatia heros.
2. Even more unfortunate: the photo in the taxobox is actually NOT of Lunatia heros an Atlantic species, but of L. lewisii, which is a Pacific moonsnail! 
Anyone agree that this article needs dividing?
Invertzoo 00:54, 17 September 2007 (UTC)
thread_title: A note
Talk:Football sign

message: I'm sorry, but either a picture of the actual football sign should be shown first or no pictures should be shown at all. Showing a picture of an American football for a radiographic sign is misleading and intellectually dishonest. —Preceding unsigned comment added by Avaron676 (talk • contribs) 21:01, 1 March 2007 (UTC)
replies: text: I don't think it is misleading or dishonest at all.  It is not uncommon to see a picture of a dinner fork in textbook side-by-side with a picture of a dinner fork deformity -- in the context of how a Colles fracture typically appears.  I think an American football is appropriate to include. In the case of spondylolysis (where one talks of the Scottie dog)... they typically draw on top of x-rays to make the point. Nephron  T|C 04:21, 2 March 2007 (UTC)
replies: text: Fine. Maybe this is just my lack of knowledge of Wikipedia, but how can an image of the actual sign be included without violating copyrights? Avaron676 23:34, 4 March 2007 (UTC)
replies: text: One has to find or create an image that is not copyrighted and where the patient has released it to be published. A few docs are around that do this-- Samir has done this for endoscopic images.  Other images, such as the one on aortic stenosis or the one on CABG are public domain... by virtue of someone making 'em PD or them being US government (which per policy doesn't copyright stuff). Nephron  T|C 02:26, 5 March 2007 (UTC)
thread_title: I'm
Talk:Treats (play)

message: Just edited this to remove irrelevant detail on the actors in the revival. Billie Piper is Billie Piper, not "Dr Who's Billie Piper". If people are interested in what the other actors have done, they'll look them up. It's not relevant to the play.  — Preceding unsigned comment added by 81.108.241.233 (talk) 21:55, 27 June 2011 (UTC)
thread_title:  Irrelevant detail on actors