Talk:Mutation rate

message: Please discuss this at the Genetic drift talk page. — Donama 06:07, 7 June 2006 (UTC)
thread_title: Merge this with [[genetic drift]]?

message: Are you sure that the numbers given for mutation rate are accurate? I could believe that rate per base pair, but not per gene. Adam Cuerden talk 03:56, 17 February 2007 (UTC)
replies: text: A related question would be: "per generation" likely refers to "per cell duplication" even in eukaryotes. So we would need an approximate figure of how that translates into generations as normally percieved in multicellular organisms.213.47.123.225 22:11, 16 June 2007 (UTC)
thread_title: Accurate?

message: "DNA viruses have mutation rates between 10^-6 to 10^-8",
"the mutation rate in eukaryotes is in generally 10^-4 to 10^-6"
10^-8 < 10^-6 => So the virus has a lower mutation rate than an animals/eukaryotes? (217.87.250.137 (talk) 13:02, 24 November 2007 (UTC)
replies: text: I was hoping to find some help with understanding the math of mutation rates (I'm not a geneticist or a molecular biologist - but do research and teaching on HIV, and I want to understand the numbers i'm teaching!!), and I was sad to see that this discussion is a bit old.  I'm wondering, though, whether the problem with the mutation rates quoted has to do with the proofreading function of DNA polymerase, which is missing in RT.  so, the errors are generated and corrected in mammals, but not in viruses (and maybe some bacteria - can't recall how efficient bacteria are at DNA proofreading) --janaki (talk) 16:25, 27 May 2008 (UTC)
thread_title:  Wrong mutation rates? 

message: This article is in terible shape right now. I'll try to get it clean up over the next few days, but any and all help is appriciated. I want to at least get the headings of everything relevent up so people can expand on them, but considering how awful it started out, I have little faith that it will get better without the concerted effort of several knowlagable people 99.137.200.197 (talk) 02:59, 2 February 2012 (UTC)
thread_title: General

message: This article would benefit from a section related to other mechanisms which may affect the rate of mutation, such as naturally occurring differences in methylation on stretches of the DNA. See [ack of DNA modification creates hotspots for mutations which begins with: "The absence of a chemical alteration called methylation on some stretches of DNA makes them especially prone to mutations, according to a paper published in PLoS Genetics in May."  — Preceding unsigned comment added by 107.197.209.255 (talk) 18:14, 20 February 2014 (UTC)
thread_title: "Hotspots" for Mutation

message: I suggest to delete the section on Mutation Accumulation Lines  that also mentions the Bateman-Mukai Method. Neither of them are explained. Mutation Accumulation Lines appear to be based on sequencing anyway, which I suggest to use as a new header for that section. Peteruetz (talk) 17:07, 15 October 2014 (UTC)
thread_title:  Mutation Accumulation Lines and Bateman-Mukai Method to be deleted 

message: In the Introduction I would like to add example of types of mutations for readers to get a clear idea of where mutation rates occur. For example: cancer. Also I would like to change the wording. I want to check and add a source to see if the sentence regarding "upper and lower limit subject to ongoing investigation" if this is still true or if it is not. 
I also would like to add an image of the point, missense and nonsense mutation giving the reader a different way to look at and understand the information.   — Preceding unsigned comment added by Lilavasquez (talk • contribs) 23:53, 16 May 2017 (UTC)
thread_title:  Chem_153A_Honors_(Spring_2017) editing