Talk:Non-24-hour sleep–wake disorder

message: I have been dealing with non-24-sleep for decades.
This morning I read this article about earth organisms (including humans) timing cycles with the lunar gravity cycle. Despite the lunar gravity being small, its rhythm is impactful. The lunar cycle times to about 24.6 hours per day (between 24.4 and 24.8).
https://www.studyfinds.org/sun-and-moon-impact-behavior/
My suspicion is: for whatever reason, my light-dark cycle doesnt work at all. So, my body defaults to the gravitational cycle instead. During the week, I have observed my cycle will "roll forward", delaying for upto an hour later compared to the previous day. As an experiment, I will try time my sleeping schedule with the local sea tides, as convenient way to stay in sync with the lunar schedule. I suspect I wake up fresh at about every other low tide. (There are about two low tides per day. My body picks one of them each day.)
Apparently, people with normal light-dark sleeping schedules, also periodically adjust their circadian rhythm to resynchronize with the lunar schedule.
Perhaps, people without the light-dark regulation, simply use the lunar day (about 24.6 hours) instead?
Anyway, I am mentioning this in case it turns out to be useful to any sleep researchers. I am hoping people like me with non-24-hour sleep can find a healthy way to regulate and schedule our routines based on the timing of tide instead of the timing of sunrise.  
— Preceding unsigned comment added by 2603:9001:6B0D:E73A:C2F:97DD:52DF:5B77 (talk) 17:48, 9 January 2022 (UTC)
thread_title:  Not light-dark cycle, but LUNAR cycle 

message: Anyone able to give a reference for the 'symptoms'? I can personally vouch for a few of them, but the plural of anecdote isn't Wikipedia ;) 82.22.141.131 (talk)  —Preceding undated comment added 05:01, 11 February 2011 (UTC)
thread_title:  Reference for "Symptoms? 

message: As someone with a 28-hour sleep-wake cycle, I'm beyond curious. And it isn't like there's a lot of information available... Aadieu (talk) 18:39, 6 October 2009 (UTC)
replies: text: That's a forum-type question, so someone's likely to archive us. I'll write on your talk page.  - Hordaland (talk) 05:27, 7 October 2009 (UTC)
thread_title:  SO... any successes in treating it? 

message: the reference link about the study of sighted patients leads to a webpage that says the 'session has timed out'. just fyi  —Preceding unsigned comment added by 68.102.166.2 (talk) 21:55, 5 January 2010 (UTC)
thread_title:  link doesn't work 

message: "For instance, a person with a 25-hour body clock would have a 25-day cycle with two weeks of good sleep and two weeks of poor sleep. But a person with a 24.1-hour circadian rhythm would drift only six minutes per day and take 241 days, or eight months, to go around the clock."
This is not how it works.  It is completely wrong - I'd delete it but I am not familiar with the literature, just what it like to live like this.  I've been "around the clock" a few times.  When on a regular day job (only two years of my life) I stayed up too late by Weds, Thu, Fri, and then slept till noon on Saturday and Sunday.  Monday was never fun.
My point is that the bit I quoted is pure crap.  One's body clock does not "store up" hours lost or gained. Huw Powell (talk) 02:25, 26 October 2013 (UTC)
replies: text: I believe the quoted bit is correct. Why do you think it indicates "storage" of hours?  If I understand your 2nd paragraph correctly, it sounds as though you may have DSPS/DSPD rather than Non-24?  --Hordaland (talk) 05:48, 26 October 2013 (UTC)
thread_title:  Some bits aren't really correct. 

message: This article defines non-twenty-four ("nine-twenty-four?) as a "sleep disorder".  However, a long-running radio public service announcement about the condition explicitly states that non-twenty-four is not a sleep disorder.
Well, which is it?  (Unsigned comment by 67.206.162.105 at 09:26, 7 March 2014) 
: I suspect that the radio "announcement" you have heard is advertising by Vanda Pharmaceuticals about their new drug Tasimelteon (trade name Hetlioz) which recently was approved (in the USA, at least) solely for Non-24-hour sleep–wake disorder (Non-24) in totally blind people.  It is unfortunate that Non-24 in sighted people and in blind people have the same name, as they have different causes; the cause of blind Non-24 is known.  In any case, Non-24 is listed as a sleep disorder in DSM-5 and in the ICSD.
: I suppose I understand the thinking behind saying that Non-24 in the totally blind is not (primarily) a sleep disorder.  These people's primary diagnosis is blindness.  The c. 50% of totally blind people who have Non-24 wouldn't have it if they weren't blind.  Their circadian rhythms are presumably entirely normal.
: Non-24 in the sighted is a neurological failure of any ability to entrain to the 24-hour cycle in nature.  It appears to be a more severe and debilitating version of DSPD. The best explanation of Non-24 that I know about is  here.
: --Hordaland (talk) 10:56, 7 March 2014 (UTC)
thread_title: A "sleep disorder" or not?

message: The format of this article is good. It is a bit strange how it bounces back and forth from "sighted" and "blind" information, but I think it is the best way for the article to be set up. That could be opened for discussion though. The only parts of the article that bugged me from time to time were the short paragraphs. There are a few paragraphs that contain one or two sentences. For example, in the Characteristics section under "sighted", there is a two sentence paragraph starting with "Non-24 can begin...". I just feel like this fragment should either be expanded on, or tied into another paragraph. That's very nit-picky though, overall the article is constructed well. Cjohnso4 (talk) 02:37, 30 April 2014 (UTC)
replies: text: Yes, it "bounces back and forth" between "sighted" and "blind" information.  I've tried to explain the reason for that in my comment in the section below.  --Hordaland (talk) 09:34, 12 May 2014 (UTC)
thread_title:  Copy/Edit 

message: I moved some of the sighted-N24 prevalence data to a more general section. The sources don't distinguish whether they're discussing sighted or Blind N24. In fact, the 140,000-in-the-EU source specifically says most of the cases are in blind people ("Epidemiology: N24HSWD is an orphan indication affecting ~140,000 in EU [1]. It occurs mainly in totally blind pple"). The article was written in such a way to say there were 140,000 SIGHTED cases in the EU and I thought that was misleading. 81.107.48.231 (talk) 12:28, 8 August 2014 (UTC)
thread_title:  Prevalence 

message: Primary sources are not allowed as references, but I think that editors watching DSPD, Non-24 and/or Bipolar will be interested in seeing 
this paper Just FYI. --Hordaland (talk) 12:24, 17 December 2014 (UTC)
thread_title:  A new study 

message: I've made fairly major changes.  While the body of the article (at least, mostly) keeps separated the information about Non-24 in the sighted, which is a primary disorder, and Non-14 in the totally blind, a condition secondary to their blindness, the lead did not make this separation plain at all.  Also, technical terms were used to excess without plain language clarification.
In my opinion, it is unfortunate that these two disorders, with their very different causes, symptoms, and populations, share the same name.  It is understandable that they do, as very little was known when they were named and they do share that non-24-hour aspect, though to different degrees.  I'm tempted to suggest that the article might better be split in two:  Non-24-hour sleep-wake disorder in the blind and Non-24-hour sleep-wake disorder in the sighted.  That can't happen without discussion!  (You think those titles are long?  It gets worse.  The latest version of the name is Non-24-hour sleep-wake rhythm disorder.)
I have tried to separate the blind version from the sighted in the lead and make it more understandable to the uninitiated.  I'll take another look after sleeping on it and also check to see if refs are missing.  
If you don't like something, or have any suggestions, please let me know!
Thanks, Hordaland (talk) 17:02, 30 April 2016 (UTC)
replies: text: Thank you for the changes, I agree that they might be very different disorders (and actually the AASM agrees), but there is currently no proof, only hypotheses. I will add what the AASM says, but we can't do much more until there is more research done in this area, so for the time being I think we should keep both sighted and blind N24 in the same article. --Signimu (talk) 02:08, 5 November 2018 (UTC)
thread_title:  Changes to the lead 

message: I updated the whole article following AASM 2015 clinical guidelines. There are several sections that are still full of original research, or not properly referenced, but they make sense so I leave them here for the time being (if someone has more time to research for example the mechanisms and causes, and particularly some good systematic review), but it would be good to do, we are about halfway to a WP:MEDRS quality sufficient article . --Signimu (talk) 02:10, 5 November 2018 (UTC)
thread_title:  Major overhaul following AASM 2015 clinical guidelines 

message: A master work on 17 subjects concluded that sleep-phase delayed subjects might be light hypersensitive and have a slow somnolence buildup: . The methods are sound (they used DLMO and melatonin suppression to respectively assess melatonin and light PRC on a subject basis), but it's only a master work. This hypothesis is I think very interesting and it's surprising noone has yet investigated it (since it is assumed that for blind people it's rather a light insensitiveness issue, but maybe for sighted it's actually the opposite?). It would be interesting I think to watch the future research on this topic. --Signimu (talk) 22:42, 5 November 2018 (UTC)
thread_title:  Non-24 in sighted as a result of light hypersensitivity and slow somnolence buildup? 

message: DPSD and Non-24-hour_sleep–wake_disorder have an enormous amount of overlapping information, which could / will be confusing to newcomers.  Given that these are rarely diagnosed, largely ignored syndromes that may not be currently broadly circumscribed as such for the foreseeable future, editors should be cautious to maintain a neutral attitude towards those who may suffer from this syndrome or others similar.  Sleep hygiene and exercise (increased heart rate to zone 2-4 for 20-60 min / week) are almost universally accepted remedies, but many cannot achieve these.  Perhaps further discussion of efficacy with regards to evidence-based therapies is warranted, along with a significant slimming of prose otherwise.  
Volunteering for this by the way, just want to understand if there's any dissident. Darkskysunflowers (talk) 10:28, 18 September 2022 (UTC)
thread_title:  Condensation of DPSD and Non-24 SWD (not merging) 

message: The box at the side of the top has the words "total blind" at the bottom, under frequency.
I didn't like to correct it in case it is correct technical language somewhere in the world, but, unless that is the case, perhaps it could be corrected to "totally" or "completely"?  
Or, indeed, to, "Blind people without light perception," which seems to be what it means in this context. That might be clearer, as "totally blind" could be interpreted comparatively subjectively. FloweringOctopus (talk) 18:01, 19 December 2022 (UTC)
thread_title:  "Total blind" probably isn't good grammar