Talk:Ulcerative colitis

message: naturally!  people take sulfasalazine tablets don't they
1.155.227.101 (talk) 00:42, 30 September 2011 (UTC)
replies: text: UC is not caused by psychiatric factors - stress can IRRITATE it, but it is not the cause.  UC can spontaneously just go away in about a quarter of the cases.  Many people follow all dietary restrictions and continue to go downhill and need surgery eventually.HammerFilmFan (talk) 16:54, 3 June 2015 (UTC)

text: Nah. While the cause of UC is not known, there is an undeniable genetic portion to the disease.  Why it happens or triggers the first flare-up is unknown, but drinking a Pepsi didn't do this to you - it would have happened anyway.  Most often, the disease seems to trigger after a mild infection of some type (such as a headcold) and the body's immune system fails to "turn off" and begins attacking healthy tissue. That's why the Talk Pages need to be restricted to the discussion of Reliable Sources, rather than a forum for the discussion of the general subject, because it is unproductive for the project. HammerFilmFan (talk) 16:58, 3 June 2015 (UTC)
thread_title:  sulfate reducing bacteria in the gut? 

message: --Doc James (talk · contribs · email) 05:46, 14 November 2011 (UTC)
thread_title:  2011 review in NEJM 

message: There is mentioned that particularly in elderly patients there is an increased risk of bowel perforation after steroid intake[ref: http://emedicine.medscape.com/article/195537-overview#showall ]. 
And, of course, steroids mask simptoms of acute abdomen, so it could be deleterious to use steroids in patients with risk of perforation because of missing the perforation.
But i couldn't find anything worth that would explain the mechanism how steroids induce bowel perforation in ulcerative colitis. Please help!  — Preceding unsigned comment added by Vldscore (talk • contribs) 18:44, 29 February 2012 (UTC)
thread_title:  Steroids increase risk of bowel perforation! 

message: The section had a citation required since Jan 2012. I have removed the citation required tag after providing appropriate reference.
DiptanshuTalk 15:50, 22 December 2012 (UTC)
thread_title:  Research 

message: 2013 BMJ 
2012 BMJ  
Doc James (talk · contribs · email) (if I write on your page reply on mine) 09:25, 27 February 2013 (UTC)
thread_title: New reviews

message: I have suffered off and on with UC for more than 30 years. Numerous colonoscopies, every test available to determine whether it was UC or Crohn's. All tests came back non specific Crohn's-colitis. The only determining factor that identified it as UC is that over the years I have found that smoking cigarrettes tends to bring the disease into remission, and when I have told my doctors that, they at first have asked me not to quote them, lol, but history has shown that smoking will help with UC and yet with Crohn's it actually worsens the condition. I have tried every drug available to man, sulphur drugs, prednisone, imuran, remicaid (I think that is what it was called - $10k a dose if I recall! None had any effect in bringing the condition into remission. Three times I have been hospitalized because the condition was so bad, one time for 30 days - after which I was no closer to remission than on day one, but without real food for a month, considerably lighter. My wife noticed a common denominator prior to my hospitalization - I had quit smoking. I read another post that UC is in many cases caused by something in the mind. I believe that to be true in my case. Although I may not appear anxious, nervous or depressed, I have always been what my parents called "a worrier". I do give a lot of thought to how I perform my job and I have held some very stressful positions, and I suppose I do overthink the future, detail etc. don't think I can change my make up though, it's the way I am, and I suppose it must be a great contributing factor as to why I suffer with UC. I am intrigued though with how smoking helps and why a healthy substitute cannot be developed based on that fact? Gum, nicorette, fake cigs, even pot do not help at all. I even tried writing to Phillip Morris to see if they would study it! but never got a reply - you would think they would jump at the chance to put a positive spin on such a killer habit. In the past 4 months, I once again quit smoking, having been free from any symptoms for close to 2 years (smoking during that time since the day I left the hospital - which by the way was the day my symptoms started to go away). In the past when I quit, I jotted down the worsening of my symptoms, little worsening the first week, gradually progressing to full blown at around 6 weeks. I would then normally pick up a cigarette and within hours feel better and within days the symptoms would be pretty much gone. This last time though, my doctor had me on a tapering dose of prednisone, from 40mg all the way down to 5mg. Although symptoms had improved, I still had active UC even though I had started smoking again. Here is the kicker - I had some foot pain last week and have been taking Hydrocodene otherwise know as Lortabs I think. It is like a miracle cure! All symptoms have completely disappeared. Foot is still aching, but heh, I'll take what relief I can get. I actually ran out of the pills and will not be taking anymore due to the addictive nature of the drug, but I felt compelled to share this story in hopes that others out there may know the answers as to why they help me, others still may find that these products may help them also. I know how desperate one becomes when UC is active, the panic to get to a bathroom, the panic never to be far from a bathroom, the need to know where every bathroom in a city is located etc. I also know the embarrassment of having to take relief when no bathroom is available, not pleasant. Please reply to this post if any of it rings true to your situation. Good luck. Atkinsx (talk) 00:14, 4 December 2013 (UTC)
replies: text: The Wike TP's are not for the discussion of a personal experience or a forum.  Please only post if you have a Reliable Source to improve the quality of the article.  I am asking an Administrator to "hat" this post, please? HammerFilmFan (talk) 16:49, 3 June 2015 (UTC)
thread_title:  Take a deep breath - smoking helps with colitis, and so does hydrocodene! 

message: S-Adenosyl methionine notes "SAMe has been studied in the treatment of osteoarthritis. SAMe reduces the pain associated with osteoarthritis. Although an optimal dose has yet to be determined, SAMe appears as effective as the non-steroidal anti-inflammatory drugs".  
Shjacks45 (talk) 10:26, 1 May 2014 (UTC)
thread_title:  Under "Alternative Medicine" I think SAMe was intended in place of S-Methyl Methionine 

message: Omega-3 fatty acids contribute to digestive system health. You haven't figured out why 5-ASA are, but NSAIDs are not, used therapeutically (yet the target inflamation)? Same reason NSAIDs promote stomach ulcers, they inhibit prostaglandins that are protective of the stomach lining as well as the rest of digestive system lining. Long term high dose use has been implicated in promoting IBD.
Shjacks45 (talk) 10:56, 1 May 2014 (UTC)
replies: text: And your reference for your statement (title and page number) is what, exactly? HammerFilmFan (talk) 16:50, 3 June 2015 (UTC)
thread_title:  Under "Alternative Medicine" and Causes 

message: The upshot of the current text is that hydrogen sulfide is detrimental. Both articles cited are over 15 years old. Newer references exist that reverse the detrimental view of H2S. Furthermore, a role in future therapeutics is being investigated. I propose updating this section.  Any thoughts among the watchers of UC? Thanks in advance for your input.
https://www.ncbi.nlm.nih.gov/pubmed/19769457
https://www.ncbi.nlm.nih.gov/pubmed/22017247
 McortNGHH (talk) 20:27, 15 April 2016 (UTC)
thread_title:  Pathophysiology - hydrogen sulfide not detrimental -> section needs revision 

message: 19:41, 24 June 2016 (UTC)
thread_title:  The cause of Ulcerative Colitis 

message: doi:10.1016/S0140-6736(16)32126-2 JFW | T@lk 09:29, 2 December 2016 (UTC)
thread_title:  Lancet 

message: Can have an ulcerative affect on the colon wall according to some sources Wikipietime (talk) 18:05, 17 June 2018 (UTC)
replies: text: Having an ulcerative effect on the colonic mucosa is very different than ulcerative colitis. Many factors can lead to ulcers in the colon (lack of blood flow, constipation, etc), which have nothing to do with ulcerative colitis.  However, if there is good quality evidence that lectin may contribute to the development of ulcerative colitis, I encourage you to add this content to the article, with references.  Rytyho usa (talk) 01:49, 23 October 2020 (UTC)
thread_title:  Lectin 

message: The article says "Dietary changes, such as maintaining a high-calorie diet or lactose-free diet, may improve symptoms.", but the reference doesn't seem to support this. Rather a linked page from the reference says "Ulcerative colitis symptoms may cause some people to lose their appetite and eat less, and they may not get enough nutrients.". While it may be true that a lactose-free diet (with appropriate supplementation) may reduce symptoms, aggravation, or onset of the condition (probably through microbiome related complex dynamics), it seems that the claim of a high calorie diet being helpful isn't backed obviously by the reference. The claim about dairy should probably be refined, but right now I suggest that the claim about high-calorie diet be dropped or be refined or qualified with peer reviewed research / a more obvious reliable source.  — Preceding unsigned comment added by Thefreeencyclopedia1 (talk • contribs) 15:57, 12 February 2021 (UTC)
replies: text: I just read the source and couldn’t find a reference to either the dairy part or the high calories. 78.152.205.15 (talk) 07:28, 23 July 2023 (UTC)
thread_title:  "maintaining a high-calorie diet" 

message: — Assignment last updated by DrDexterN (talk) 20:17, 14 November 2022 (UTC)
thread_title: Wiki Education assignment: WikiProject Medicine Fall 2022 UCF COM

message: Hello, I am a fourth-year medical student from the University of Central Florida, and I am enrolled in a WikiProject course. I have chosen this article and plan to edit it by changing wording and structure of some sentences that may be misleading or may use medical jargon. I plan to explain the meaning of various terms that would not be well known to most viewers (ex. Skip lesions, ileus, biologics etc.). The article seems to have most citations in place, but there are a few areas that indicate a need for citations. I hope to add references for those areas.
I also hope to add more information in the “Differential diagnosis” section of the article, as many of the diagnoses listed include vague descriptions. Additionally, I will update the information regarding medications and their side effects.
I would be happy to take any suggestions for changes as well! Rasika ucf (talk) 00:01, 8 November 2022 (UTC)
thread_title:  Work Plan 

message: I learned so much from reading this article, especially from your contributions. Overall, I think your contributions were relevant, concise (which is not easy to do), important, and necessary additions to the article. From reading through your work plan, you achieved everything you hoped to accomplish. The information added is also understandable to the intended WP audience.
Great job editing and changing the wording and structure of sentences that were misleading or used medical jargon. A specific example of this was when you concisely defined “systemic signs of toxicity,” as “fever, chills, weight changes.” Contributions such as these are important for the understanding of the average reader.
I found it helpful that you explained the meaning of various terms that would not be well-known to most viewers, such as toxic megacolon.  
I appreciate how many references you contributed to the article (13!). I think your inclusion of quality secondary sources really takes this article to the next level, especially for viewers who may be interested in further reading on the topic.
I enjoyed reading and learning from your additions on primary sclerosing cholangitis, pyoderma gangrenosum, anemia, and hidradenitis suppurativa - it was well-done, concise, and packed with an informative punch accessible to the layperson! Your large addition to the imaging section really improved that portion of the article, which was very trim before.
You went above and beyond to meet your goal of expanding the differential diagnoses section. Thank you for explaining how to distinguish Crohn's disease, infectious colitis, other forms of colitis, and graft versus host disease from ulcerative colitis. 
I spot-checked the links and they are all working! The article flows understandably and meets readability guidelines (no sentences longer than 26 words). You made use of periods and few commas or semicolons. 
A suggestion for improvement could include adding more of the wiki links to different terms in the article such as: anal fissures, abscess, and infectious colitis.
Medabloom (talk) 18:59, 17 November 2022 (UTC)
replies: text: Thank you so much for your feedback! I really appreciate your help and will definitely try to incorporate some more wikilinks! Rasika ucf (talk) 14:03, 18 November 2022 (UTC)
thread_title:  WikiProject Medicine Fall 2022 UCF COM, Peer Review 

message: As the title states, the Mayo Endoscopic Score should be mentioned somewhere in the article. Either under the Endoscopic subheading under the Diagnosis section and/or under the Progression/Remission subheading under the Prognosis section. After all MES is the common endoscopic index recommended in guidelines and considered a quality indicator, and widely used in clinical trials and clinical practice.  Instantwatym (talk) 18:26, 10 September 2023 (UTC)
thread_title:  The Mayo Endoscopic Score should be mentioned somewhere in the article