lflage/wiki-talks huggingface dataset:
Talk:Topoisomerase IV

message: The article mentions that this is not DNA Gyrase. Now I do not doubt the statement, but to me, as a semi-naive user, I wonder why one enzyme has a somewhat unique (DNA Gyrase), but the other
has a numbered-scheme name only (Topoisomerase IV). I am not expecting of Wikipedia to go in depths about this, but what I'd like to see is a more clear distinction here. Perhaps as a 
first step, it may help if the DATE of naming/discovery could be added to BOTH DNA Gyrase and Topoisomerase IV. This may help visitors to "dig" into the history of how the enzymes got
their names (and perhaps then eventually figure out why one is named this way and the other one not). 2A02:8388:1641:4700:BE5F:F4FF:FECD:7CB2 (talk) 12:12, 15 April 2017 (UTC)
thread_title:  Naming
Template talk:Marathon series

message: While I love the template, I think the colors sort of clash a little. — Preceding unsigned comment added by MrHen (talk • contribs) 
:For the record, this is the template as it appeared at the time of the above comment. --DocumentN (talk) 22:20, 4 February 2008 (UTC)
thread_title:  Colors 

message: I'm not sure whether to include a link to Cortana Letters in the template, but I'm leaving it out for now. For one thing, it could mislead people into thinking Halo and Marathon are the same universe; and the letters were written years after the Marathon game series ended, by someone who was never involved in the original games, so they're kind of on the border of fan fiction. --DocumentN 19:02, 6 October 2007 (UTC)
replies: text: Also, further indecision about whether to add Double Aught. --DocumentN 19:03, 6 October 2007 (UTC)
thread_title:  [[Cortana Letters]] 

message: For the record, I still consider Pathways Into Darkness a game in the Marathon series. --DocumentN (talk) 00:24, 4 February 2008 (UTC)
thread_title:  PID
Talk:Gp41

message: Hello, I am a student assigned to edit this article. Here are my proposed changes: 
1. Overall - The section will be expanded to be at least as comprehensive as the gp120 Wikipedia page.
2. Chemistry - The current wikipedia page talks about a "cascade of conformational changes" but does not go into detail about them, so the "Function" section can be expanded to include those details using the equine analogous protein gp45. Additionally, the fusion and activation processes can also be expanded upon. The structure of gp41 can also be described in detail using the following article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594655/ and https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909398/.
3. As a drug target - There are a number of potential inhibitory pathways that can be included in this section.
If anyone reading this has any advice or concerns, please let me know. Neildsilva (talk) 19:26, 21 February 2017 (UTC)
thread_title:  Wiki Education Foundation-supported course assignment Proposed Changes
Talk:P21

message: ;I have a little bit of an issue with this statement...
I think there was like 1 study that showed this compared to the hundreds of others that showed just the opposite. Because there is no citation I'm not sure which paper this editor was referring to but if it's this one, the authors found that deletion of p21 prolongs the lifespan of telomerase-deficient mice with dysfunctional telomeres. These mice had dysfunctional telomeres. I guess I just want a citation, otherwise I'd think we should go with the bulk of the evidence that suggests that p21 IS very important in tumor suppression. 
—―
 —―
Niubrad (talk) 22:20, 20 November 2014 (UTC)
thread_title:  p21 knockouts don't have higher cancer rates? 

message: I would like to add a source regarding p21 and apoptosis but don't know how:
Almond, J. B. and G. M. Cohen (2002). "The proteasome: a novel target for cancer chemotherapy." Leukemia 16(4): 433-43.
The statement, p21 would'nt under any circumstance lead to apoptosis is not correct as you can read in that paper. --134.2.164.29 (talk) 16:44, 28 February 2010 (UTC)
replies: text: Thanks a lot, Boghog2! --134.2.167.20 (talk)  —Preceding undated comment added 19:18, 28 February 2010 (UTC)
thread_title:  Apoptosis 

message: The picture of the molecular model shown in the english article is wrong. It does not show p21, but p21 bound to PCNA. This is confirmed when following the link to the original structure.  — Preceding unsigned comment added by Taurec81 (talk • contribs) 07:51, 7 September 2018 (UTC)
thread_title:  Picture/Structure is misslabeled
Talk:T7 phage

message: The tone of the last two sentences of the article bothers me.  —Preceding unsigned comment added by 24.209.44.86 (talk) 15:33, 14 March 2010 (UTC)
thread_title: Untitled

message: I do not know whether there is copy/paste content. I tried to change one sentence so far; not sure if I will try to change more. I am mostly concerned that my changes could get reverted, so in this case it may be better if someone else makes the changes to improve the article. 2A02:8388:1603:CB00:3AD5:47FF:FE18:CC7F (talk) 01:04, 9 December 2017 (UTC)
thread_title:  Copy/Paste content 
Talk:Fort Loramie High School

message: Generally, mainstream high schools are regarded as notable. However this article cites no reliable sources that would establish its notability. The contents of the article appear to be composed of personal knowledge, poor quality sources, and self-references. Articles in this condition about schools are particularly dangerous because it is very difficult for uninvolved editors to verify that the details are accurate. Once the problems listed above are fixed, the tag should be removed. DPRoberts534 (talk) 20:02, 28 January 2015 (UTC)
thread_title:  Refimprove January 2015
Talk:Blue–white screen

message: if any one is good at putting diagrams in (my formating skill are sub par), i created one and up loaded it to commons for general use,
http://commons.wikimedia.org/wiki/Image:Blue_white_assay_Ecoli.jpg
--Dylan2106 15:12, 8 November 2007 (UTC)
thread_title:  diagram 

message: It may be helpful to mention that blue-white screening can be run on a gel which helps with further confirmation of whether or not the white colonies actually produced the gene with the insert.  Aaqquino (talk) 21:15, 11 February 2016 (UTC)
thread_title:  running a gel
Talk:U.S. Ski & Snowboard

message: This draft article - awaiting approval - is very much in the news today. Draft:Peter Foley (snowboarding) 2603:7000:2101:AA00:11B7:346D:E7B2:CD58 (talk) 21:39, 9 August 2023 (UTC)
thread_title:  Draft article
Talk:Replication fork

message: This is part of DNA replication and as such I think it should be merged into that article. - tameeria 19:27, 8 March 2007 (UTC)
replies: text: I agree too. The replication fork section in that article says basically the same thing. Mikael Häggström (talk) 18:58, 21 May 2009 (UTC)
thread_title:  Proposed merge 

message: Correct me if I'm wrong, but isn't the lagging strand synthesized 3' to 5'? Not 5' to 3' as listed on the page.
:Kind of both. It's 3' to 5' relative to the template strand, and 5' to 3' relative to the newly synthesized strand. Mikael Häggström (talk) 18:58, 21 May 2009 (UTC)
replies: text:  I also had a hard time with the issue of Directionality (molecular biology) in this article. I rewrote it a little, in the hope to bring some clarity. I'd be happy to discuss my edit with you here. Debresser (talk) 13:51, 4 September 2009 (UTC)
replies: text:  Please notice that I also made minor wp:mos and wp:internal links fixes. Debresser (talk) 14:20, 4 September 2009 (UTC)
thread_title:  Direction 

message: The subsection Replication_fork#Lagging_strand is unclear because of the unexplained technical jargon, or just plain bad English. What is the meaning of "being intrinsic" in this subsection, for example?
Furthermore, this subsection seems to be a mix of the edits of two editors with possibly slightly diverging opinions. However, when that leads to unclear text, these ideas have to either presented separately, or blended into an organic whole. Debresser (talk) 14:25, 4 September 2009 (UTC)
thread_title:  Unclear subsection 

message: The replication fork page says that the leading and lagging strands are the templates for reproduction.  I have always learned that the strands are the new ones that are produced.
76.20.138.21 (talk) 12:10, 8 December 2009 (UTC)
thread_title:  Template??? 
Talk:Gamma-glutamyltransferase

message: add GGT deficiency please!!!!!!!!!  —Preceding unsigned comment added by 76.174.42.22 (talk) 04:49, 17 June 2008 (UTC)
thread_title:  add GGT deficiency 

message: Apparently there are 2 stub articles for this: Gamma-glutamyl_transpeptidase and Gamma-glutamyltransferase. Someone with better knowledge should clean these up. Thanks.
unsigned comment by User:70.54.202.152 moved from article.  Boghog2 (talk) 04:57, 17 February 2009 (UTC)
replies: text: These two articles have now been merged into one.  Boghog2 (talk) 05:19, 17 February 2009 (UTC)
thread_title:  Duplicate articles 

message: "Others include NSAIDs, St. John's wort, and aspirin."
Aspirin is a NSAID.  — Preceding unsigned comment added by Sudabogulanbalik (talk • contribs) 12:32, 16 January 2011 (UTC)
replies: text: Fixed just now. Nurg (talk) 05:29, 28 July 2016 (UTC)
thread_title:  NSAIDs and aspirin? 

message: Glow green for go: scientists develop cancer marker 28/11/11 12:13 CET
University of Tokyo's Yasuteru Urano
99.181.131.33 (talk) 00:16, 30 November 2011 (UTC)
thread_title:  Resource "spray which makes [[carcinoma]]s glow green"
Talk:Philip C. Habib

message: I can help expand this article by creating a subsection called Lebanon and providing more information about Habib's work there using Al-Jazeera's War of Lebanon (Harb Loubnan) documentary. However, I am not sure if there is any interest. Also, if I create a 'Lebanon' subsection, I guess a 'Vietnam' subsection is in order, and I do not have much information about his work there. Shaque 20:51, 16 February 2007 (UTC)
replies: text: Given that Habib was Lebanese and that he pretty much singlehandedly managed to get a temporary peace between Israel and Lebanon, I think that it was a significant achievement, deserving of the subsection you mention.  Let me know if you have any questions about the subject; I have the book on it ("Cursed is the Peacemaker"), I'm the liquidator of Habib's estate, and friends with his widow, so I can run any questions past her. Bricology 20:28, 15 April 2007 (UTC)
thread_title: Work in Lebanon

message: Given the mess made by Arafat and his PLO in the West Bank and Gaza from 1994 on, and the disaster of Hamas taking over Gaza, one must ask the question as to whether this fine diplomat should have been sent on his mission to Lebanon. I can imagine a better world for everyone, most especially the Palestinians and the Lebanese, had the Israel Defense Force been allowed to eliminate Arafat and the PLO in 1982. 216.99.185.50 18:13, 22 June 2007 (UTC)
thread_title: Brilliant Diplomat, Bad Policy

message: I have a problem with these lines:
"In 1990 Nicaragua held a free and fair election. President Ortega lost to Violeta Chamorro and stepped down."
Firstly, it describes events that occurred after Habib's involvement in the region ceased, so I don't believe it's relevant. Secondly, it implies that there had not been free and fair elections under the Sandinistas. Thirdly, it neglects to mention the threat of continued US sponsorship of the Contras if their favoured candidate was not elected.
Lapsed Pacifist (talk) 13:12, 1 January 2009 (UTC)
thread_title:  Nicaragua
Talk:Charlotte Greenwood

message: American Film Institute -  "The American Film Institute was founded by a 1965 presidential mandate announced in the Rose Garden of the White House by Lyndon B. Johnson—to establish a national arts organization to preserve the legacy of American film heritage, educate the next generation of filmmakers, and honor the artists and their work. Two years later, in 1967, AFI was established, supported by the National Endowment for the Arts, the Motion Picture Association of America and the Ford Foundation." 
The above is for informational purposes. — Maile  (talk) 23:45, 2 May 2020 (UTC)
thread_title:  American Film Institute 

message: Internet Broadway Database - "Operated by the Research Department of The Broadway League, a trade association for the North American commercial theatre community." IBDB  "is an online database of Broadway theatre productions and their personnel, including lengths of runs, lists of casts and creators, awards and nominations, and past box office grosses. Its research department maintains historical data on individual playhouses and productions. In addition, many reference documents, including weekly box office grosses and season-by-season statistics, are available to the public, journalists, and scholars via the website."
The above is for informational purposes. — Maile  (talk) 23:45, 2 May 2020 (UTC)
thread_title: Internet Broadway Database
Talk:W-inds. Mega Mix (album)

message: Isn't this a single, not an album? On the w-inds. main page, it's listed as a single, and I believe it was generally treated as a single release...  —Preceding unsigned comment added by Word to Mother (talk • contribs) 18:38, 29 September 2008 (UTC)
thread_title: Album? What?
Talk:Roland MC-909

message: "The operating system also had some bugs and annoying features"
Words such as the 'annoying' concern me as they are derived from the opinion of the author and are not based on encyclopedic fact, I have added the POV banner to this page for this reason; and for other POV points within the article (one of which I have already removed).
Additionally, I do not believe the "Upgrade from MC-505" section is needed either - but others may not agree.
Leftblank 20:54, 16 February 2007 (UTC)
thread_title: Untitled

message: CHECK ROLAND CLAN WEB SITE for info using xD cards
Roland MC-909 Tip/Trick: using a H256 MB xD card via a xD to SmartMedia adaptor - from this site.
—DJFLEX-mk2 20:43, 8 September 2007 (UTC)
thread_title: Links

message: I have doubts about the list of bugs described as still existing after OS 1.23; in fact, I do have the SMF loading issue, but absolutely none of the others. There are project shortcomings rather than bugs at this stage.
I propose merging the two "bugs" paragraphs into a single, shorter one.
The Roland MC-909 is no more built by Roland Corporation (it was entirely built by a small team of enthusiasts people, at the end of 2005, they were laid off by Hewlett Packard).
 
—DJFLEX-mk2 03:06, 31 May 2010 (UTC)
thread_title: Unsolved bugs
Talk:Myrosinase

message: Nice to see that there is a "theory" about plant defence, but did anyone measure 'what where God's or Natures purposes' of these measured biochemical pathways?
The healthy anti-carcinogenic IsoThioCynates(ITCs) need indeed Myrosinase to form from some types of vegetables. Here a very detailed article:
http://lpi.oregonstate.edu/infocenter/phytochemicals/isothio/
MM 84.81.213.44 06:14, 2 December 2007 (UTC)
thread_title: Controverse: "plant defense" vs. very healthy, anti-cancer

message: This article should be merged with Thioglucosidase, they are synonyms. PatríciaR msg 20:13, 6 September 2011 (UTC)
thread_title:  Merging with [[Thioglucosidase]] 
Talk:PDE1

message: Phosphodiesterase I --2A02:8109:A100:1196:0:0:0:B20F (talk) 09:40, 21 September 2019 (UTC)
thread_title:  duplicate 

message: https://en.wikipedia.org/wiki/PDE1#cite_ref-Jeon_4-4
This citation to Mr. Jeon & associated co-authors is only a link to a preview. This is a very important piece of information. I don't have money to purchase the paper or a license via an institution to look at the paper. If anyone has access to this paper, please post on Wikimedia a screenshot of the specific section of the paper where this claim can be substantiated. Remember, it's just a preview without any relevant information concerning this citation and this is a VERY important piece of information.
Sincerely,
CEO of Singularitarian Technologies Corporation
John Lasheras  — Preceding unsigned comment added by 47.20.225.225 (talk) 14:17, 29 October 2019 (UTC)
thread_title:  PDE1 Inhibition leading to PDE5 Inhibition can't be substantiated. Did anyone access the paper? Can you provide a screenshot of the specific quote? 

message: https://imgur.com/QGDmGmt
Here's the proof of the citation, I paid for the research paper and it's true according to the research by Mr.Jeon and associates. So, I answered my own question and for anybody else that is curious.  — Preceding unsigned comment added by SINGULARTECH-JohnLasheras (talk • contribs) 18:13, 29 October 2019 (UTC)
thread_title:  Reply:PDE1 Inhibition leading to PDE5 Inhibition can't be substantiated. Did anyone access the paper? Can you provide a screenshot of the specific quote?
Talk:Disney Cinemagic (UK & Ireland)

message: why cant the us have this
Because Disney doesn't care about us. By the way, HAPPY 1 YEAR TO CINEMAGIC! WizardDuck 03:39, 17 March 2007 (UTC)
thread_title:  Cinemagic US 

message: Has anyone seen that Disney Cinemagic (UK) have changed their logo? This Wikipedia page says that France will get a different logo than us, but our new one looks nearly like it. Anyone willing to edit, I'm not very good at it. Zoton2 19:15, 3 September 2007 (UTC)
thread_title:  New Logo
Talk:Tumor suppressor gene

message: This article should NOT be merged with the tumor suppressor gene. They are NOT the same thing.
*Okay, merge tag removed. Abductive (reasoning) 21:01, 6 June 2010 (UTC)
thread_title: Merge?

message: I'm wondering if this can be made a little clearer in the following way. Yes, it is true that tumor suppressor genes tend to act through a recessive mechanism in that both alleles need to be taken out to exhibit a disease. However, tumor suppressor genes overwhelmingly show a dominant pattern of inheritance. Retinoblastoma is an example. Both alleles of retinoblastoma must be mutated to show the disease. This is a recessive mechanism. However, it is listed as a dominant disease, because a child who inherits a faulty allele will almost certainly acquire a second through mutation. So when examining a pedigree of retinoblastoma or Lynch Syndrome, both of which involve mutations of tumor suppressor genes, (mismatch repair in the case of Lynch), they are dominant in transmission. Can we make that clear in this article? It is not the mechanism that determines whether or not a disease is recessive/dominant, but rather the pattern of vertical transmission, from parent to progeny.  — Preceding unsigned comment added by Creightonian (talk • contribs) 01:30, 16 December 2010 (UTC)
thread_title:  Tumor suppressive genes are recessive? 

message: Are the genes that code of checkpoints most likely to be protooncogenes or tumor suppressor genes? Explain. 41.223.117.37 (talk) 17:08, 19 January 2022 (UTC)
thread_title:  Course assessment.
Talk:Eleanor of Portugal, Holy Roman Empress

message: I have added her birth and death places. 24.31.169.252 (talk) 11:01, 30 December 2009 (UTC)
thread_title: Additions

message: In one of the earlier paragraphs it refers to her as a “he”...  — Preceding unsigned comment added by 2606:A000:5281:AD00:B0D1:2377:AE5B:2131 (talk) 11:53, 21 July 2020 (UTC)
replies: text: Where exactly? I can't see it. DrKay (talk) 15:55, 21 July 2020 (UTC)
thread_title:  Typo
Talk:Beatrice of Portugal, Countess of Alburquerque

message: :The following is a closed discussion of a requested move. Please do not modify it. Subsequent comments should be made in a new section on the talk page. Editors desiring to contest the closing decision should consider a move review after discussing it on the closer's talk page. No further edits should be made to this discussion.
The result of the move request was: moved. Uncontested RM. (closed by non-admin page mover) ❯❯❯ Raydann(Talk) 00:02, 2 October 2023 (UTC)
replies: text: Beatrice of Portugal (died 1381) →  – Several women named Beatrice of Portugal, one is treated like a primary topic and every other uses a noble title for disambiguation. This one is the sole exception, using the year of death instead. A noble title is a more natural disambiguation and will create consistency. Killuminator (talk) 18:44, 15 September 2023 (UTC)
thread_title:  Requested move 15 September 2023
Talk:Infanta Branca, Lady of Guadalajara

message: There is a move discussion in progress on Talk:List of Portuguese monarchs which affects this page. Please participate on that page and not in this talk page section. Thank you.  —RFC bot 21:31, 4 September 2009 (UTC)
thread_title: Move discussion in process
Talk:Infanta Doroteia of Braganza

message: I notice that the name on this talk page does not match the name on the article, and to go back and forth between them redirects are used.  I don't know how to correct this problem, but if someone could help, that would be great! 1bandsaw (talk) 17:51, 6 April 2015 (UTC)
thread_title:  Talk page location?
Talk:Infanta Isabel Maria of Braganza

message: There are rumours that Virginia Charlotte Schalck (1822-1907) was her out-of-wedlock daughter, who was raised by her father, the German merchant Johann Christoph Friedrich Gerstlacher (1775-1850), in Lisbon. Are there any proofs for this?  46.82.244.77 (talk) 10:22, 29 October 2021 (UTC)
thread_title:  Daughter
Talk:Infanta Maria Francisca of Portugal

message: Where exactly was she buried at? It states the Royal Pantheon of the House of Braganza, Gosport Catholic Church, and Trieste Cathedral. Even if she was transferred and reburied, this sequence makes no sense.--The Emperor's New Spy (talk) 16:48, 16 September 2012 (UTC)
thread_title:  Burial
Talk:Maria of Portugal, Hereditary Princess of Parma

message: She is known as Portugal. I will move her if no one else does :) LPC (talk) 16:16, 2 December 2010 (UTC)
thread_title: Untitled

message: Has it ever been noted that the heir general of Infanta Maria after her descendant Elisabeth Farnese were the Kings of Spain thus making them heir general of the Kings of Portugal? --The Emperor's New Spy (talk) 18:12, 18 September 2012 (UTC)
thread_title:  Spain
Talk:List of interstitial cells

message: The heading above implies that this is an article, while being a disambiguation page implies not being an article.  I'm going to clean up the page based on WP:MOSDAB.  If it's really an article and not a dab, undo my edits and remove the disambig template. -- JHunterJ 23:16, 6 September 2007 (UTC)
thread_title: Disambiguation or article

message: Thanks everyone for contributing, consensus was to keep. My feeling is that a move to a page like List of interstitial cells might have support? Ping to  who proposed this idea. --Tom (LT) (talk) 07:33, 22 August 2018 (UTC)
replies: text: To me, "type" sounds taxonomical, and this isn't a taxonomical class. I'm comfortable with List of interstitial cells. --Anthonyhcole (talk · contribs · email)  14:00, 22 August 2018 (UTC)
replies: text: Either way is fine with me.  -- RoySmith (talk) 14:01, 22 August 2018 (UTC)

text: Thank you for taking this on, FourViolas. And thank you for that link to Cell type. --Anthonyhcole (talk · contribs · email)  13:20, 23 August 2018 (UTC)
thread_title:  What to do from here
Talk:Sancha of Portugal (born 1264)

message: There is a move discussion in progress on Talk:List of Portuguese monarchs which affects this page. Please participate on that page and not in this talk page section. Thank you.  —RFC bot 21:31, 4 September 2009 (UTC)
thread_title: Move discussion in process

message: The Sancha who was beatified was Sancha, Lady of Alenquer, daughter of King Sancho I of Portugal, along with her sister Theresa. --Maragm (talk) 20:01, 2 October 2020 (UTC)
thread_title:  Not a saint
Talk:B-cell receptor

message: Needs more description. Too little content. 
Pramit57 (talk) 22:41, 14 November 2014 (UTC)
thread_title: Untitled

message: Please define "Ag" 
Minnsurfur2 (talk) 16:40, 15 January 2015 (UTC)
thread_title:  Need definition 

message: References 4, 5, 8, 9 and 11 are the same
Minnsurfur2 (talk) 17:53, 15 January 2015 (UTC)
thread_title:  Redundant references