Talk:Neisseria gonorrhoeae

message: add culture media info!!  —Preceding unsigned comment added by Tkjazzer (talk • contribs) 06:34, 28 January 2008 (UTC)
thread_title:  Add popular media info 

message: i know tetracyclins are used for chlamydial infections, but what is this bit I just read about "uncomplicated gonococcal infections all about."  I read it in a book with no further explanation. If you know, please add it to the article with a source. Thanks. 207.151.238.43 (talk) 22:18, 16 July 2008 (UTC)
thread_title:  "Tetracycline in uncomplicated gonococcal infections" 

message: CMR review doi:10.1128/CMR.00010-14 JFW | T@lk 21:36, 6 July 2014 (UTC)
thread_title:  Resistance patters 

message: Hi there, editing this page as part of my graduate course.
Some initial thoughts as there are many detailed improvements this page requires:
1)	The lead/introduction is a bit choppy (seems piecemeal created). Definitely should at least mention antibiotic resistance as this is the main concern with Ng currently in the scientific world and does a poor job of an overall summary of the article
2)	Missing a citation after the last sentence of first paragraph in the lead
3)	In surface proteins LOS is mentioned, which is in fact not a protein, a better section should probably be put together titled “surface molecules.” Additionally, LOS is referred to as LPS in at least one instance
4)	There is mention of antigenic variation but not phase variation, both different but important aspects of persistent Ng
5)	There is nothing on the colonization of the epithelial lining before transcytosis occurs 
6)	There is no information about the serum resistance of Ng and its use of complement regulatory proteins to evade complement killing, another important aspect of its survival
7)	Antibiotic resistance should be updated as there are further confirmed cases of resistance now to combination treatments 
8)	There are citations and information taken directly from primary literature, and while this is intuitive from a scientist’s prospective, Wikipedia does not wish for this type of sourced information to be included in its articles (8, 13, 14, 15, 16, 21, 22, 23, 32, 35 is a news article (total of 10 of 43) 
9)	“Dynamic polymeric protein filaments called type IV pili allow N. gonorrhoeae to adhere to and move along surfaces.” Sounds plagiarized (no offense to the writer of this portion), although cannot confirm as I do not have access to the book which is cited
10)	Survival of gonococci is a very vague section heading with little information. Technically this could include immune evasion, colonization, etc. 
11)	There is one subheading, organization definitely needs to be improved
12)	Disease section is all about symptoms not the establishment of infection
13)	The coverage seems to be neutral fortunately with an emphasis on proven scientific fact 
14)	The images in the article are helpful but they are specific for identification and drift all the way down throughout the article. A depiction of the lifecycle of infection would be helpful. 
15)	Not many people are working within the talk page with one another to improve the article 
Overall a lot of restructuring of this article is necessary. References certainly need to be fixed to reflect secondary literature. Additionally, three is quite a bit of information missing from this article that is critical about Neisseria gonorrhoeae such as phase variation, the specifics of how it infects/interacts with the host cells, and evasion of killing by the complement system to name a few. 
Let me know what you think about these and other potential issues with the article as there are certainly many. I will hopefully be making meaningful contributions to the improvement of this article throughout the following months. 
Pz921518 (talk) 19:51, 3 October 2018 (UTC)
thread_title:  Working to edit this page 

message: Hello all,
I have done a substantial amount of editing in an attempt to better this article. A summary of my edits can be found below. 
-A creation of an infection subheading and information pertaining to the establishment of infection (entire section)
-Edits to the antigenic variation section for clarity, and removal of Opa protein changes for inclusion in phase variation section
-A creation of a phase variation subheading and information on this process during infection.
-Inclusion of Opa protein information previously in article under the antigenic variation portion
-Treatment section was updated to reflect most recent guidelines as stated by the CDC (and WHO)
-Added serum resistance section, set up so that it should easily be elaborated on below the first paragraph
-Cleaned up the flow of the disease section so it didn’t read as individual lines of text and random information
-Amended the “surface proteins” section title to “surface molecules” to cover the discussion of LOS in that section
For those looking to edit this article in the future, please do not simply add free standing sentences of information that seemingly belongs in a section. Please look through the text and find the place that is appropriate and alter the paragraphs to reflect your intended changes. This will allow for much smoother editing and allow the article to be improved as a whole instead of creating more piecemeal parts that will need edited together. 
Pz921518 (talk) 13:54, 29 November 2018 (UTC)
thread_title:  Recent Edits