Talk:Compounding

message: There is an article in the German Wikipedia which
is closely related:
Eigenherstellung von Arzneimitteln
I am not sure whether it is exactly equivalent.
If an expert feels that these are exactly
equivalent, then this cross reference should
be added someplace in the body of the article:
[de:Eigenherstellung von Arzneimitteln]
Thomas.Hedden (talk) 15:50, 27 May 2011 (UTC)
thread_title:  Equivalent German term 

message: There might be a valid criticism here, but the prose is argumentative rather than encyclopedic, and is not up to Wikipedia standards.  Here is the section removed if someone feels up to reworking it.  
The stance of the FDA has been that each time a drug is compounded it creates a “new drug”.  Since that “new drug” has not received FDA approval, the FDA then claims the compound is adulterated and therefore illegal. The illogic of such a position is clarified when one considers the actual practice of medicine in the United States, which uses multiple medications simultaneously (polypharmacy).   
While many people take two or more medications daily, very few prescription drugs are studied when combined together.  This polypharmacy is impossible to study because of the difficulty and the cost of conducting a full-scale study of each drug combination.  For example say there are three hundred drugs available for a doctor to choose from.  If a patient is taking an average of six prescription drugs daily, there would be over 10^14 possible drug combinations that individual patient could take.  It would be impossible to study that many drug combinations.  
Yet the polypharmacy is practiced universally and the FDA accepts it.  Using the FDA’s own logic, combining various medications together is illegal if the patient swallows all the drugs after they have been compounded into one capsule… but let that same patient individually take the same multiple prescription drugs and swallow them one at a time… then the FDA has no problem with it.
 
To begin with, some official FDA statements concerning their position on this would be required to support a claim of this nature. MaxEnt 03:12, 9 November 2007 (UTC)
replies: text: See Sec. 608.400 - Compounding of Drugs for Use in Animals  (CPG 7125.40), by US FDA Office of Regulatory Affairs. --Una Smith (talk) 05:17, 24 April 2009 (UTC)
thread_title: Polypharmacy POV section removed

message: A search of "compounding" produces this page, with a link to "compound interest" if that is what you were looking for.  There are no pages for "pharmaceutical compounding" or "compounding pharmacy", although this result is first.  Considering that "to compound" is a verb with at least three meanings, and pharmaceutical compounding is definitely not the most common usage, it seems that perhaps a title change or disambiguation is necessary.
Pamplemousse gnome (talk) 10:08, 19 April 2008 (UTC)
thread_title:  Disambiguation/title change 

message: This article still has a slant, as shown by passages like this one: "It was during this time that patients and physician became dissatisfied with the “one size fits all” attitude of the large Pharma companies. Physicians searching for drugs to treat their patients led to the reawakening of the ancient art of prescription compounding." -- Skylights76 (talk) 15:04, 29 June 2008 (UTC)
replies: text: Is this better?  (It sounded very much like someone's advertising plan.)  Feel free to kill more of the promotional material.  WhatamIdoing (talk) 05:43, 30 June 2008 (UTC)
thread_title:  NPOV 

message: I marked this as of questionable relevance as it's not directly related to compounding, and if in the article at all, probably shouldn't seem quite so prominent Persephone12 (talk) 23:15, 17 July 2010 (UTC)
thread_title:  Human Drugs 

message: There's papers published for both sides. I'd like to keep debate on the Bioidentical hormone replacement therapy page, not here. Persephone12 (talk) 21:05, 18 July 2010 (UTC)
replies: text: I think BHRT is probably a common reason for people to wonder what compounding is, so mentioning that context here is probably appropriate.  WhatamIdoing (talk) 23:38, 18 July 2010 (UTC)
thread_title:  Bioidentical Hormone Replacement Therapy 

message: I think that it would be best to merge the history of pharmacy section in this article and that in the main Pharmacy article, to create a new History of pharmacy article, similar to the History of medicine article. Or at least merge the history section in compounding to the main pharmacy article and then link to the main pharmacy article. Persephone12 (talk) 21:41, 18 July 2010 (UTC)
replies: text: This doesn't pertain to merging, but I believe a sentence in the second-to-last paragraph of the history section is incorrect: "Pharmacists were trained to compound the preparations made by the drug companies, but they were unable to do it efficiently on a small scale." Shouldn't it end, "on a large scale"? Toddmatic (talk) 08:35, 16 September 2010 (UTC)
thread_title:  History of Pharmacy 

message: Here's a New York Times story, written as background to the NECC case, which lists other incidents of problems with compounding pharmacies. It discusses where the compounding pharmacies get their ingredients from, which seems to be largely China. It also discusses some of the regulatory issues. 
http://www.nytimes.com/2012/10/23/health/before-meningitis-outbreak-group-advised-how-to-avoid-fda.html?
Before Meningitis Outbreak, Concern at F.D.A. Over Compounders
By WALT BOGDANICH and SABRINA TAVERNISE
Published: October 22, 2012 
--Nbauman (talk) 00:59, 23 October 2012 (UTC)
replies: text: Yes, that is a good one, though I have not yet used it.  I did add quite a bit of copy today--some of it needs to edited due to occasional poor sentence construction (related to the always present copyright problems).  The article still needs a fair amount of work.  Gandydancer (talk) 17:17, 23 October 2012 (UTC)
thread_title:  NYT story 

message: Perhaps someone can use this  to improve the article further. 67.243.4.94 (talk) 12:32, 17 April 2013 (UTC)
thread_title:  BusinessWeek article that may be helpful 

message: This article has been marked with  since December 2012.  To partially address this, I put the per-country details in this article into alpha order.  What's really needed is some editing to meet the WP:SS guidelines.  72.244.206.214 (talk) 21:06, 18 February 2014 (UTC)
thread_title:  Split US details 

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thread_title:  External links modified