lflage/wiki-talks huggingface dataset:
Talk:Eogyrinus

message: "it has strong tail to help it swin very fast nearly 125kmh"
Ignoring the spelling error, isn't 125 km per hour a bit fast for any animal? 71.217.114.221 00:48, 15 February 2007 (UTC)
replies: text: Good catch! This was just some nonsense added by an anonymous user. I removed the paleobox since current consensus is to avoid them. ArthurWeasley
Is this the same animal as Proterogyrinus? 62.164.247.12 (talk) 19:59, 26 March 2008 (UTC)
thread_title: What's this now?
Talk:Metabotropic receptor

message: The references on this page are not written in correct Wiki format, if anyone could provide the full reference, that would be ideal. Bozman7000 (talk) 23:57, 25 May 2011 (UTC)
thread_title:  Referencing issues 

message: Because the article mentions only GPCRs.Sivizius (talk) 00:25, 21 March 2021 (UTC)
replies: text: I edited first sentence to address this question.Knoitalno (talk) 22:57, 18 November 2021 (UTC)
thread_title:  Are all metabotropic receptors GPCRs?
Talk:Neurotransmitter receptor

message: how long it took me to make that table.. i deserve a award.. haha, i also added alot of radome links and edited a bit.plus the add pick code. i do that for every article i work on, saves me time. Roy Stanley (talk) 20:38, 15 January 2008 (UTC)
thread_title:  if only you knew.. 

message: This help request has been answered. If you need more help, please place a new  request on this page followed by your questions, or contact the responding user(s) directly on their user talk page.
Someone put so much time into those tables. However, the receptor table could be organized in a way that conveys more information. It would be great if someone who is more familiar with how tables work could sort the receptor types into metabotropic and ionotrpic. You can find out which ones are which on the wiki pages for each receptor type (note among the receptor types listed as of June 15, 2011, glutamate, Acetylcholine and 5-HT (serotonin), have both metabotropic and ionotropic receptor subtypes.) More information about specific receptors can be found here: http://www.rndsystems.com/molecule_group.aspx?g=682&r=9. 
It would also be great if someone could make the neurotransmitters table more relevant to this page by adding information relevant to receptor activity (i.e. 5HT1B ligation inhibits glycinergic signaling, Ang II-mediated AGTR-2 signaling inhibits growth, promotes apoptosis, and induces nitric oxide release, Molecules such as amphetamine both competitively inhibit DA uptake, and induce DA release through the DAT, increasing the rewarding property of DA, etc.) --Xttina.Garnet (talk) 10:03, 15 June 2011 (UTC)
replies: text: That table has been formatted in a rather non-Wiki way. My guess is that someone started with a table in MS Word and then tried to adapt it. See Help:Table for more common ways of making tables for Wikipedia. If you have an idea for reorganizing the table but are not sure how to format it, my suggestion is to begin drafting it up on this talk page by writing down the text of what should be in each table cell. Use any old convention. When your content is ready and you just need formatting help, either go to WT:MCB to attract some biologists who might take an interest, or post at WP:Editor assistance/Requests. Good luck. EdJohnston (talk) 05:51, 3 November 2011 (UTC)
replies: text: I went ahead and transformed the ugly styled html table to a wikitable. This should be now easy for every contributor to add more fields since the markup is really easy. Feel free to add a new  if you need further help! mabdul 11:12, 8 November 2011 (UTC)
thread_title:  Please Help: Have Information, Intimidated by table formatting
Talk:Ansovinus

message: Bibliotheca Hagiographica Latina 555.  https://archive.org/details/bibliothecahagio01boll/page/90/mode/2up?ref=ol&view=theater&q=ansinovinus p. 90. --142.163.195.18 (talk) 12:40, 13 March 2021 (UTC)
thread_title:  BHL ref
Talk:Histamine receptor

message: How can the same H1 type receptors cause both smooth cell constriction (bonchoconstriction) and smooth cell relaxation (systemic vasodilatation)? Ca2+ signalling cause constriction.
I think the vasodilatation is caused by the H2 receptors. Vasodilatation should be removed from the H1 part of the table.
193.6.168.249 (talk) 14:03, 16 December 2016 (UTC)
thread_title: Histamine receptor discrepancy

message: Can someone expert in this provide a simple explanation in layman's language, please? Onanoff (talk) 03:50, 7 February 2020 (UTC)
thread_title:  Layman's explanation 

message: Hi, Im student from Uskudar University. I edit this article (Histamine receptor) as an assignment for my course (recent development in biotechnology ). I already completed Wikipedia training modules to be proficient in Wikipedia editing. I would appreciate any support. Best wishes, Rahaf Bin Mahfouz RAHAF.2001 (talk) 20:10, 25 January 2024 (UTC)
thread_title:  I’m new editor
Talk:Sensitive skin (electronic device)

message: This page should be used for cosmetics, and the existing content should be moved into some other topic. -- Sy / (talk) 00:20, 15 February 2007 (UTC)
thread_title: This

message: *Expand and update
*Refs needed
*Remove any advertising
Chaosdruid (talk) 01:00, 13 March 2011 (UTC)
thread_title: Robotics attention needed
Talk:Ephrin receptor

message: We feel that the comment "this article is on a subject of low importance within molecular and cellular biology" is not adequate.
Ephrins are becoming more and more important in cancer biology. A molecule active on Ephrin B4, subject of complex debate betweeen pharmaceutical firms, was discussed on September 4 at the International Association for the Study of Lung Cancer.
Google has 419,000 pages on Ephrin.
I suggest replacing "low importance" by "growing interest".
Healthvalue 06:45, 6 September 2007 (UTC)
thread_title:  Rating too low 

message: Please write a more clear introductory paragraph. Is it an article about ephrins or about their receptors? What do they do? Why a single article about both ephrines and eph receptors? The introduction gives a headache to a newbie reader. Best regards, --CopperKettle 08:56, 17 August 2009 (UTC)
replies: text: I've started a separate page for Ephrins in Russian Wiki. If anybody does a split here, notify me or find the page (Эфрины) by yourself and add the interwiki. Cheers. --CopperKettle 16:29, 28 August 2009 (UTC)
thread_title: Please clarify

message: The page for "Ephrin receptor" was redirected to a page titled simply "Eph receptor" as receptors related to Eph are properly termed "Ephs" and not "Ephrin receptors". All discussion in the future should be contained on the "Eph Receptor" page.
Armadaskier324 (talk) 22:45, 13 December 2011 (UTC)
thread_title: Important Redirect

message: As has been mentioned above, but incorrectly reverted by another user, these proteins are Ephs or Eph receptors. They are not Ephrin receptors. Eph receptors name comes from "erythropoietin-producing hepatocellular receptors", not Ephrin receptors. Ephrins are another type of ligand/receptor (depends on your point-of-view) with another Wikipedia article dedicated to it, which bind Ephs.  — Preceding unsigned comment added by Enozkan (talk • contribs) 03:40, 26 April 2016 (UTC)
thread_title: Incorrect Name
Talk:Insulin-like growth factor 1 receptor

message: The molecular weights of the alpha and beta subunits of IGF1R should be included in the article. I believe this is readily available information, e.g. <https://datasheets.scbt.com/sc-101703.pdf>.  — Preceding unsigned comment added by Mmkstarr (talk • contribs) 01:03, 17 March 2016 (UTC)
thread_title:  Molecular weights of the subunits
Talk:Glycine receptor

message: Citations for endogenous agonists are needed and missing Momeara (talk) 16:50, 28 March 2019 (UTC)
thread_title: Untitled

message: Could someone add in the history of its discovery please? 109.156.177.94 (talk) 02:17, 15 January 2020 (UTC)
thread_title:  History
Talk:Progesterone receptor

message: I don't see the benefit in discussing the broad class of nuclear receptors in an article which specifically addresses only PR. 67.183.154.215 (talk) 08:47, 17 November 2012 (UTC)
replies: text: Agreed. We already have an article on nuclear receptors and that material does not need to be repeated here. Hence I have deleted the background section from this article. Boghog (talk) 18:34, 17 November 2012 (UTC)
thread_title:  Background section
Wikipedia talk:Articles for deletion/Log/2007 February 14

message: Wikipedia:Articles for deletion/Alfredo DeOro may've been misfiled.  It is hours old, but does not appear in Wikipedia:Articles for deletion/Log/2007 February 14 (as of this writing). — SMcCandlish [talk] [contrib] ツ 00:22, 15 February 2007 (UTC)
replies: text: Admin Malevious fixed it. — SMcCandlish [talk] [contrib] ツ 00:56, 15 February 2007 (UTC)
replies: text: Im not an admin :O --Malevious  Userpage •Talk Page• Contributions 00:59, 15 February 2007 (UTC)
thread_title: Orphaned AfD today?
Talk:Glucocorticoid receptor

message: While the GR/relaxin connection is intriguing, it is not exactly clear what is going on here (see for example http://www.fasebj.org/cgi/reprint/03-1120fjev1).  The bell shape GR/relaxin binding curve is very puzzling.   Therefore I thought it much safer (especially for article meant for a wide audience) to use dexamethasone instead of relaxin as an example of a GR agonist. Boghog2 18:26, 19 April 2007 (UTC)
thread_title:  GR ligands 

message: A sentence in the current version of this article reads: 
* the [GR] complex activate anti-inflammatory proteins, and repress pro-inflammatory proteins, in the cytosol. 
This to me implies a non-genomic effect.  Rapid, non-genomic actions of glucocorticoids have been observed and membrane associated GR has been proposed to mediate for these effects.  However to the best of my knowledge, this mechanism remains controversial.  In contrast transactivation and transrepression mechanisms of GR action (which are both genomics effects) are well established.  Hence I believe the above sentence should be modified to read:
* the activated [GR] complex up-regulates the expression of anti-inflammatory proteins [in the nucleus], and represses the expression of pro-inflammatory proteins in the cytosol [by preventing the translocation of other transcription factors from the cytosol into the nucleus]. 
I realize this wording is more complicated, but I believe it is more accurate. Cheers.  Boghog2 (talk) 15:23, 8 March 2009 (UTC)
thread_title:  Genomic vs. non-genomic effects 

message: Endocrine Rev doi:10.1210/er.2014-1010 (24 pg) JFW | T@lk 05:54, 23 June 2014 (UTC)
thread_title:  Review 

message: The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response.
I can barely make sense of that, grammatically. 
The GR is expressed in almost every cell in the body and regulates genes controlling the developmental, metabolic, and immune responses.
That's now parallel, but is it correct? — MaxEnt 14:01, 22 September 2018 (UTC)
thread_title:  Non-parallel structure
Talk:Vitamin D receptor

message: Hello. I have a BA from an Ivy League college and something of a scientific training, but little background in biology; that said, I do not understand this article, and think it would be more useful to the general reader or student if the major points were summarized in non-specialist language. Thank you.  — Preceding unsigned comment added by 75.132.12.83 (talk) 05:49, 18 January 2014 (UTC)
thread_title:  reading level & vocabulary 

message: Are there drugs that target the gene or the protein ? Rod57 (talk) 16:22, 24 September 2010 (UTC)
thread_title:  therapeutics targets 

message: Calcitriol receptor has only 34 current Pubmed listings (only 2 since 2000) whereas Vitamin D receptor has over 6000.  I propose that the balance of the terminology in this article should reflect common usage. Jrfw51 (talk) 10:34, 2 June 2017 (UTC)
replies: text: Good to see the change has now been made. Jrfw51 (talk) 08:50, 18 July 2020 (UTC)
thread_title:  Vitamin D receptor terminology
Talk:Peroxisome proliferator-activated receptor

message: where can i get ppar-delta activating medicaments? —The preceding unsigned comment was added by 84.61.15.154 (talk) 12:50, 31 March 2007 (UTC)
replies: text: What would you like to achieve with that? JFW | T@lk 21:23, 27 November 2007 (UTC)
thread_title:  human ppar-delta activation 

message: We should perhaps quote Steven Nissen's destruction of muraglitazar as an antidiabetic. Obviously, we still know too little about PPAR to predict firmly what modulation will do to bone and coronary artery. JFW | T@lk 21:23, 27 November 2007 (UTC)
replies: text: RE: Muraglitazar: I presume you mean this?   Boghog2 (talk) 21:47, 27 November 2007 (UTC)

text: RE: PPAR modulators effect on bone: this looks sobering:  Boghog2 (talk) 21:47, 27 November 2007 (UTC)
thread_title: Muraglitazar

message: I have a couple of questions I hope someone here can help me answer. First, seeing as plant sterols can also reduce cholesterol and I beleive, increase the HDL, does it have any impact on PPAR's? Also, are there any known natural or herbal alternatives that also activate PPAR?  —Preceding unsigned comment added by Interestedperson (talk • contribs) 05:07, 4 January 2009 (UTC)
thread_title: PPAR/plant sterols/and natural alternatives?

message: This was dropped on the article:
This sounds almost like rumour, and a bit more logical explanation would be useful. What might the beneficial effects be of PPAR ligand use? JFW | T@lk 22:35, 24 March 2013 (UTC)
replies: text: The effect is mediated specifically by PPARδ and activation of PPARδ increases running endurance (see for example ). Boghog (talk) 22:49, 24 March 2013 (UTC)
thread_title:  Banned? 
Talk:Zeatin

message: I don't think that zeatin is in coconut milk. Coconut milk contains rather kinetin.HlTo CZ (talk) 22:47, 5 March 2016 (UTC)
thread_title: Untitled

message: — Assignment last updated by IsaqueBrandao (talk) 19:47, 7 December 2023 (UTC)
thread_title: Wiki Education assignment: CHEM 378 - Biochemistry Lab - Fall 2023
Wikipedia talk:List of infoboxes/Proposed/Infobox Poetry

message: I made this infobox for poems. I fear that there may be too many options, and the "Poem" may be better than "Poetry", or what to do with all of Shakespeare's sonnets, but this is what this talk page is for. GracenotesT § 00:28, 15 February 2007 (UTC)

message: I quite like the parameters.  All include information that better summarizes the form of the poem for poetry articles.  I'm not too keen on the color though but overall I think it wouldn't hurt to add to any poetry article.¤~Persian Poet Gal (talk) 19:47, 26 February 2007 (UTC)
thread_title: Comments

message: Poems really benefit from being read-aloud, how about a option for audio (from wiki commons)Back ache (talk) 08:22, 16 February 2021 (UTC)
thread_title:  Audio
Talk:ABC model of flower development

message: "In 2004 the characterization of sepallata1,2,3 triple mutant in Arabidopsis has led to the formulation of the ABCE model, which consider the importance of class E genes for the development of the floral organs."
Could somebody find the reference for this please, as it would greatly enhance this article, and I would personally be interested to read about it.  Thank you. Zsingaya 10:02, 26 September 2007 (UTC)
thread_title:  Class E 

message: Shouldn't the title of this page be "ABC model of flower development" rather than "ABC Model of Flower Development" per Wikipedia:Naming conventions (capitalization)? Kingdon (talk) 20:51, 31 December 2008 (UTC)
thread_title:  Lowercase? 

message: The ABC Model of flower development was first proposed by George Haughn and Chris Somerville in 1988.  Genetic control of plant morphogenesis.  Developmental genetics 9:73-89.  —Preceding unsigned comment added by 128.189.191.56 (talk) 01:02, 16 September 2010 (UTC)
thread_title:  Haughn and Somerville 

message: Most of the intro has been copied to Plant development. --Ettrig (talk) 06:38, 27 October 2016 (UTC)
replies: text: The plant development article should have a summary of the content here, not a copy. This is the primary article on the subject of the ABC model. --EncycloPetey (talk) 01:06, 28 October 2016 (UTC)
replies: text: Hmm. The intro should be a summary. So what is the problem? --Ettrig (talk) 06:29, 28 October 2016 (UTC)
replies: text:  You mean, besides the copying without attribution to the source, your typos, and failure to summarize? --EncycloPetey (talk) 19:30, 28 October 2016 (UTC)
replies: text: Hmm, I am not a mind reader, especially not when the target is at an unknown place probably far from me. So I answered about the problem that you thought you saw and commented, lack of summary. Since the intro should be a summary, copying the intro should result in putting in place a summary. If you don't think it is a proper summary, then you can of course improve it. But the problem you are then fixing is not mine. Wikipedia:Splitting says attribution can be made in the edit summary. That is what I did. So neither do I understand your complaint about without attribution. --Ettrig (talk) 20:05, 28 October 2016 (UTC)
thread_title:  Copy
Talk:General transcription factor

message: Nothing is mentioned about the general transcription factor J.  — Preceding unsigned comment added by 78.91.83.84 (talk) 11:39, 10 October 2013 (UTC)
thread_title:  TFIIJ 

message: --Skoch3 (talk) 06:51, 7 January 2008 (UTC)
thread_title:  Is FACT complex really considered a general transcription factor? 

message: Is there a difference between basal transcription factors and general transcription factors?  I always thought the terms were interchangeable, but I might have always been wrong.  There is no entry for "basal transcription factor".  For some reason "basal factor" redirects to "transcription factor".  Is there a reason for that?
On another note, on this page it is mentioned that TFIIA is not a real basal transcription factor (although it must be a general transcription factor?), but on the main page for TFIIA it is said to be "one of several general (basal) transcription factors (GTFs)..."    
Any help in clearing this up is appreciated!   Forluvoft 15:43, 14 October 2007 (UTC)
thread_title:  Basal transcription factors
Talk:T-box transcription factor T

message: 1/15/17 DennisPietras (talk) 03:26, 16 January 2017 (UTC)
thread_title:  moved out of unassessed on the genetics project 

message: 07/17/19 I think that planarians do not have a known homolog for Brachyury despite being well studied. Perhaps the language should be changed to "most" or something similar.  — Preceding unsigned comment added by 146.244.235.83 (talk) 22:19, 17 July 2019 (UTC)
thread_title:  not present in all bilaterians 

message: Ten years ago you asked for a clarification of a rather incomplete sentence.  That sentence was cut short in this edit.  I now tried to make it a bit clearer by restoring a bit of the origin.  Is this sufficient for removing your , in your opinion? JoergenB (talk) 18:48, 4 March 2020 (UTC)
thread_title:  Clarification(?)
Talk:Nuclease

message: OK, I'm new to doing anything in Wikipedia bar reading it, so please bear with the newbie!
I've got several points on this page, though lack the skill to do it, and would appreciate others views before I risk learning in depth how to do it!
1) This page talks almost exclusively about restriction endonucleases, and the 'restriction nuclease' link comes through to this page. I would suggest the page is renamed 'Restrction Endonuclease' and a seperate page created to cover the broader 'nucleases' family.
2) The citations for Linn and Arber's two papers on the methylation-restriction system in the late 1960s are:
Linn S., Arber, W. (1968). Host specificity of DNA produced by Escherichia coli, X. In vitro restriction of phage fd replicative form. Proc. Natl. Acad. Sci. USA. 59:1300-1306
Arber, W., Linn S. (1969) DNA modification and restriction. Annu. Rev. Biochem. 38:467-500
3) In the introduction, there is the sentence "One of these enzymes cleaved methylated DNA, while the other cleaved unmethylated DNA at a wide variety of locations along the length of the molecule". I believe this is incorrect- the first enzyme (methylase) adds a methyl group to the DNA, and is linked to an accurate page for 'methylase'.
4) In the 'Site-specific nuclease' section is the phrase 'The term "endonuclease" applies to sequence specific nucleases that break nucleic acid chains somewhere in the interior...'. Internal cutting of the nucleic acid is correct, but endonucleases are not necessarily sequence specific.
Thank you for listening.
England Expects 20:10, 28 February 2007 (UTC)
replies: text: Point 3 was incorrectly changed from 'methylated DNA' to 'cleaved methylated DNA' during Revision as of 15:00, 24 May 2006. I still don't want to mess up the page, though, so I'll wait for someone more responsible to come along. England Expects 20:22, 28 February 2007 (UTC)
replies: text: I'm not sure whether we should really be saying nucleases gave birth to the biotechnology industry - I think we'd be better putting in a reference to molecular biology, which is the field I think it's really risen rise to. Thoughts? England Expects (talk) 17:00, 4 April 2008 (UTC)
replies: text: Maybe nucleases gave birth to the Genetic engineering? (Redeemer079 17:54, 4 April 2008 (UTC)
replies: text: Yes, I think that would be perfect. England Expects (talk) 10:03, 9 April 2008 (UTC)

text: There needs to be resolution of Exonuclease, Endonuclease, Nuclease, and Restriction Endonuclease.  As of now, the categorizations are muddy and inconsistent.  —Preceding unsigned comment added by 99.157.202.150 (talk) 17:40, 7 April 2008 (UTC)
thread_title:  Cleanup 

message: Noticed a problem, but didn't have time to fix it.
References 5 - 12 seems to be the same reference.
Jajava (talk) 22:29, 31 August 2018 (UTC)
thread_title:  Cleanup References 

message: A picture would be helpful here. Jobonki (talk) 21:37, 4 December 2014 (UTC)
thread_title:  Picture
Talk:Mala (seasoning)

message: the wiki said it's a seasoning??? As a Chinese I have to say that   — Preceding unsigned comment added by 46.20.99.100 (talk) 03:56, 5 June 2022 (UTC)
thread_title: isn't 麻辣 an adj in Chinese?

message: This is the sauce that's used with Ma La Tofu, right?  On Chinese menus in the United States, it's always spelled "Ma La" (without a space).  Badagnani 00:37, 15 February 2007 (UTC)
thread_title:  Tofu? 

message: The Tofu article says:  "In the Shanghai region it is called málà dòufǔ (麻辣豆腐)."  Is this correct?  Badagnani 00:46, 15 February 2007 (UTC)
thread_title:  Same as Shanghai version? 

message: Why was butter just removed without comment? Badagnani 03:14, 24 October 2007 (UTC)
thread_title: Butter

message: Is this sauce commercially available? The article discusses it as if it is always prepared from scratch. Badagnani 03:17, 24 October 2007 (UTC)
thread_title: Commercially available?

message: Isn't the character better translated as "numb" (or can we add this term)? Badagnani 03:18, 24 October 2007 (UTC)
thread_title: Anæsthetization
Talk:Juan Reynoso Portillo

message: This one is badly named, with no space between name and parenthetical; merge with the (musician) article.  Gene Nygaard 00:36, 15 February 2007 (UTC)
thread_title: Untitled
Talk:Lattice truss bridge

message: Over railways in UK.  There are many attractive 19th century examples, still in use.  Shall I add a photo?
Dendrotek 00:37, 15 February 2007 (UTC)
replies: text: Please do - Leonard G. 00:40, 15 February 2007 (UTC)
thread_title:  Lattice Footbridges
Talk:Anthony Lun

message: Anthony Lun is a renowned composer in Hong Kong, Japan and the Chinese music world with a colourful career spanning over 20 decades. He is also listed in the Chinese wikipedia. --Bohemiannomad 00:38, 15 February 2007 (UTC)
thread_title: Untitled