Talk:Polycystic ovary syndrome

message: Cortisol levels seem to be critical to PCOS. Why no mention?  —Preceding unsigned comment added by 75.82.70.58 (talk) 06:24, 10 May 2009 (UTC)
thread_title: cortisol

message: All you have to do is google "PCOS support group" and you will get literally scores of precise links where there are hundreds of people waiting to answer all your questions in warm fuzzy manners. Once again, wikipedia is not a source of medical advice unless you want to risk getting it from an anonymous 15 year old (I am not exaggerating), nor is it a support group or discussion forum. It seems harsh, but this page is especially hard hit. I will move all the above to an archive. Thanks for understanding. alteripse 21:05, 28 May 2007 (UTC)
thread_title: To patients looking for advice about their own symptoms

message: I have deleted a bunch of external links to support groups and magazine articles about PCOS.  The biggest problem is that half of the websites were listed twice (except the Australian group, which had four links), but in general I believe we need to remember that Wikipedia is not an advertising opportunity for our favorite organizations.  Women with PCOS are smart enough to do their own Internet searches if they want more resources. WhatamIdoing (talk) 03:00, 27 November 2007 (UTC)
replies: text: Agree. cheers, --7swords (talk) 09:49, 8 December 2007 (UTC)
thread_title: Killing the link farm

message: An anon added unsourced information about gestational diabetes recently.  It was promptly removed.  It might be worth sorting that out.   is a (very) recent systematic study on the issue, and I found its conclusion slightly unusual:  The odds ratio is 2.89, but they'd don't trust it.  WhatamIdoing (talk) 15:00, 2 September 2008 (UTC)
thread_title:  Gestational diabetes 

message: Thought my source could be used as an additional resource for those accessing this PCOS page. Northwestern University's Feinberg School of Medicine (http://www.pcos.northwestern.edu/) provides information for those women wanting to get involved in PCOS research studies and whether certain genes increase a woman's chance of getting PCOS. Makofin (talk) 20:14, 19 November 2008 (UTC)
thread_title:  To Women Looking for Information on PCOS Research Studies 

message: This article previously mentioned trans fats as a potential cause of PCOS, but the entry was removed, mainly because the two sources ( and ) actually had not studied on people with PCOS, so their conclusions cannot be held as be valid for people with PCOS. My opinion in this case is that, because of the potential controversy of the subject, a reliable medical source (and one that specifically includes people with PCOS) is necessary for any mention of trans fats in the Cause section.Mikael Häggström (talk) 10:45, 21 September 2011 (UTC)
thread_title:  Trans fats as a cause? 

message: 50 pages! doi:10.1210/er.2011-1034 JFW | T@lk 11:33, 9 December 2012 (UTC)
replies: text: doi:10.1210/jc.2013-2350 - new endocrine society guideline. JFW | T@lk 12:05, 26 December 2013 (UTC)
replies: text: Shorter review in Am J Med doi:10.1016/j.amjmed.2014.04.017 JFW | T@lk 22:27, 11 October 2014 (UTC)
thread_title:  Review about PCOS and insulin resistance 

message: this is for the discussion of the myo-inositol reference inserted a few minutes ago. As mentioned, this is a primary source, and so frowned upon by WP:MEDRS standards. But I've already engaged on user's talk page, so this is mainly for completeness' sake. I think the discussion should probably go here before re-inserting it, if it's found to be worthwhile to re-insert. -- [ UseTheCommandLine ~/talk ]# ▄ 04:03, 17 August 2013 (UTC)
thread_title:  alternative treatments 

message: Bold claims are made that it isn't ovarian in nature in the lede, but zero citations. While modern medical science can change views rapidly in some areas, such changes always require a citation when documented. If citations are not found soon, I'll request Wiki Medicine to conduct a review/rewrite of what was once a B class article, but is far from being an F- article currently.Wzrd1 (talk) 06:17, 7 November 2014 (UTC)
thread_title:  Since I last reviewed this article, significant uncited POV has arrived 

message: Lotrozole appears to be more effective than clomiphene in inducing ovulation. It has a higher percentage of live births and the same ammount of congenital anomalies. For some reason i can't edit the page. 
Here's the source: http://www.nejm.org/doi/full/10.1056/NEJMoa1313517  — Preceding unsigned comment added by 193.2.8.42 (talk) 15:00, 27 January 2015 (UTC)
thread_title:  Treatment for infertility: lotrozole 

message: about this dif by .  Sources there are:
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* Source #1 is a review from 1998 and is too old per WP:MEDDATE.  Sources 2 and 4 are WP:PRIMARY and fail WP:MEDRS. Source #3 is a spam link not acceptable for any content in WP.
* I initially left content based on source #1, but searched pubmed for a recent review and took the most recent one that discussed supplements, and used it here.  The whole section from that article is as follows: "ALTERANTIVE THERAPIES FOR POLYCYSTIC OVARY SYNDROME.  There is an emerging body of literature on the beneficial effects of complementary and alternative medicine (CAM) in reducing the severity of PCOS symptoms and metabolic complications. Acupuncture has been shown to improve insulin sensitivity, lower androgens and improve menstrual irregularity [71]. Herbal medicines and dietary supplements may have some benefit, but studies are small, uncontrolled and nonrandomized. Alternative therapies require further investigation before they can be confidently recommended."  Jytdog (talk) 12:42, 22 April 2015 (UTC)
replies: text: Source number one (the 1998 review) also does not appear to mention any of the minerals in the text added. Doc James (talk · contribs · email) 16:45, 22 April 2015 (UTC)
thread_title:  dietary supplements 

message: This comprehensive article from pubmed / hormones.gr explains in-depth the issue of Anti-Mullerian-Hormone excess in PCOS women and the effect on the development of the leading follicle in menstrual cycle resulting in the common ultrasound picture of "cystic" ovaries: http://www.hormones.gr/721/article/the-clinical-significance-of-anti-m252llerian-hormone%E2%80%A6.html . I'd recommend to read the article fully and update the corresponding section of causes, diagnosis and treatment here in this wikipedia article. A possible way to restore menstrual cycle in PCOS women suffering from excessive AMH-increase would then be to "pump out" dysfunct follicles using either downregulation or alternating menstrual cycles with and without hormonal contraceptives and after 4 months seeing the result of having normally functional follicles and developing leading follicles as every other woman in reproductive age without PCOS would do.
There are recent studies in pubmed about detailed sample values of AMH and their effect on pregnancy and live birth rates showing a close relationship of AMH and the success of reproductive medicine in PCOS women: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518483/ . Also measuring AMH levels can be used to assess the success of metformin or glitazone therapy of PCOS: http://www.ncbi.nlm.nih.gov/pubmed/25935176
All in all, nearly unbelievable why the role of AMH in PCOS women is so widely unknown seemingly...
Malv0isin (talk) 02:28, 12 September 2015 (UTC)
thread_title:  PCOS and anti-mullerian-hormone as a cause for menstrual cycle arrest 

message: http://www.nature.com/ncomms/2015/150929/ncomms9464/full/ncomms9464.html , 10000 patients, 100000 controls, seems like finally an adequate-in-number study about PCOS. I would say this qualifies as being as good as a review, so how about updating the whole Causes section of this article with the new insights about EGF-Receptor and FSHB-locus and AMH associated with PCOS susceptibility alleles. Damn interesting stuff.
Also I'm missing the part about TSH and Hashimoto's thyreoiditis which is long-known (since 2004) and wide-spread-known as being associated with PCOS. Malv0isin (talk) 15:48, 2 November 2015 (UTC)
replies: text: An anonymous editor added a link to a gene database for PCOS from the Biomedical Informatics Centre of India. I removed it from the "Cause" section to the "See also" section, as there's no genetics section.Wzrd1 (talk) 21:31, 21 January 2016 (UTC)
replies: text: It was removed as "not a see also", if anyone finds it worth the effort, here is the reference. PCOSKb a database on PCOS related genes from the Biomedical Informatics Centre of India http://www.pcoskb.bicnirrh.res.inWzrd1 (talk) 14:34, 22 January 2016 (UTC)
thread_title:  New Nature Study about genetic causes of PCOS 

message: It's simply not clear, that PCOS is caused by ELEVATED ANDROGENS (male hormones). It just says "symptoms due to a hormone imbalance". What does that mean??? It's not clear enough 182.255.99.214 (talk) 10:44, 26 January 2016 (UTC)
replies: text: Actually, it's multiple hormones being imbalanced that is related to PCOS.131.131.64.210 (talk) 13:12, 26 January 2016 (UTC)
replies: text:  Yes but it's mainly male hormone. That's why you get male hormone effects. Even though it IS multiple hormones... 182.255.99.214 (talk) 21:10, 26 January 2016 (UTC)
replies: text: Per the source you inserted into the article, "High levels of androgens (a type of hormone) or signs of high androgens, such as having excess body or facial hair". Signs without measurable elevated androgens are still counted as PCOS, despite the lack of elevated androgens. There can be androgen hypersensitivity, estrogen hyposensitivity, mutations of either sex hormones or other factors involved where androgens are normal.Wzrd1 (talk) 21:19, 26 January 2016 (UTC)

text: I agree with you, but the reality is PCOS is hard to define. It's defined as 2 of 3 criteria, only of which 1 is hyperandrogenism. But it's the easiest way to explain it to a general non-medical audience. Or else you'd have to list all 3 criteria. What do you suggest User:Wzrd1? 182.255.99.214 (talk) 12:51, 11 March 2016 (UTC)
replies: text:  I've changed it to net effective male hormones. So this would help cover less estrogen, or estrogen hyposensitivty, or mutations in either sex hormones, because we're talking about net effective 182.255.99.214 (talk) 12:52, 11 March 2016 (UTC)
thread_title:  Make it clear 

message: doi:10.1056/NEJMcp1514916 JFW | T@lk 16:16, 7 July 2016 (UTC)
replies: text: Pathogenesis in Endocrine Reviews doi:10.1210/er.2015-1104 JFW | T@lk 13:54, 31 July 2016 (UTC)
thread_title:  NEJM 

message: " Myo-inositol and D-chiro-inositol both seems to be effective in reducing hyperandrogenism and improving ovulation in PCOS. "
This review does not appear to be pubmed indexed? Doc James (talk · contribs · email) 23:58, 21 December 2017 (UTC)
thread_title: Pubmed indexed

message: *PCOS Program at Monash University -Yupik (talk) 16:14, 20 July 2018 (UTC)
thread_title:  Monash University publishes new guidelines (July 2018) 

message: There is growing evidence that children to mothers with PCOS have a higher probability of being diagnosed with autism. Is this relevant information that should be incorporated into the article?
https://www.nature.com/articles/mp2015183
https://www.nature.com/articles/s41398-018-0186-7  — Preceding unsigned comment added by 85.226.149.234 (talk) 10:50, 24 August 2018 (UTC)
replies: text: The information is too new. Further studies are needed to verify whether this association is really there or not and we should wait for some high-quality reviews to discuss the material before adding it to the PCOS article. Good question! TylerDurden8823 (talk) 14:47, 24 August 2018 (UTC)
thread_title:  Link to autism 

message: the 'Definition" section should not be at the beginning of article (should be in 'diagnosis')--Ozzie10aaaa (talk) 13:42, 13 October 2021 (UTC)
replies: text: It's not the typical approach, but the definition of PCOS is contested, so it might be relevant.  For example, there has been a proposal that biological males also have PCOS, despite having no ovaries, no ovulation, no excess androgens, etc. WhatamIdoing (talk) 01:25, 22 December 2021 (UTC)
thread_title: definition

message: Its an hormone disorder, therefore obesity is not a risk factor, rather a symptom or sign. 2.28.187.166 (talk) 23:19, 13 March 2022 (UTC)
thread_title:  Obesity as risk factor 

message: I think the subsection on "Public figures" within the "Society and culture" category could be considered superfluous trivia and should be removed, but I would like to seek the opinions of others before proceeding. Mooonswimmer 21:16, 19 August 2023 (UTC)
replies: text: You might be interested in Wikipedia:Manual of Style/Medicine-related articles#Notable cases.  In general, including a few famous advocates or celebrities is sometimes appropriate.  I think that a paragraph (sentences like "Chris Celebrity has appeared in public service announcements and raised money for research") would always be more encyclopedic than a bare list of names. WhatamIdoing (talk) 21:24, 19 August 2023 (UTC)
replies: text: Thank you for linking to that passage. I will check out any significant coverage of prominent figures with the condition and try to construct a coherent paragraph. Mooonswimmer 21:30, 19 August 2023 (UTC)
thread_title:  Unnecessary trivia 

message: — Assignment last updated by Nicoleschully (talk) 19:17, 25 April 2024 (UTC)
thread_title: Wiki Education assignment: Health Psychology