Talk:Three prime untranslated region

message: Pleusm (talk) 15:24, 1 March 2013 (UTC)

message: This article was completely revised by a group of students at Boston College as part of a Developmental Biology class. Pleusm (talk) 16:35, 4 April 2013 (UTC)
thread_title: Untitled

message: *Brief introduction to mRNA regulatory elements
*UTResource 3' UTR analysis
*UTRome.org 3' UTRs in nematodes
*Medical Subject Heading: 3' Untranslated Regions
Category:RNA
Category:Gene expression
===Peer Review===
Overall, the article turned out really well with everything new added and edited.  The content of the subject is strong with good examples supporting the concepts and useful pictures to help with understanding some of the structures discussed.  Also, it is well written in a "wikificated" manner where laypeople will be able to understand the scientific information presented.  I also liked how you guys ended on an optimistic note with the future development section.
The first two paragraphs giving a brief summary and definition of 3'-UTR is very strong and gave a good overview of what is to come in the section below.  The second of the two seems a bit long for its purpose and could be edited down a bit since you repeat some of the information later in the other sections.  Also, I noticed that there was no citation in your first paragraph; I only comment on this because our ambassador said there should be one in every paragraph.
The physical characteristics section has good information, but the way it is presented seems choppy and a bit awkward at some times.  I think what may help with it is to add a little more information explaining some of the features instead of just jumping from one to the next or drawing conclusions prematurely.  One specific area I found a bit awkward and could a bit of work was when discussing the G+C percentage of the mRNA transcript.
The role in gene expression section to me was your strongest!  You guys have really good content here that is presented well and easy to understand.  Also, the examples of the different regulations really helped to prove the points and the pictures chosen helped as well.  My only suggestion is to add a picture of a stem-loop structure since it is discussed often and I feel like could be very useful as well to the laypeople to understand the mechanisms more.
The methods of study section needs a little more work.  Adding a couple sentences about the techniques of the mapping and sequencing would improve it so readers can understand how the results are determined and analyzed.  Also, the first sentence is a bit off-putting.  When you say the methods are tedious, then the reader will assume the paragraph will be as well and will not want to read the rest of it.  Mention that it can be tedious further in the paragraph and have a topic sentence stating the methods used to analyze the 3-UTRs.
The disease section has interesting information but I feel like its just a list of alterations that will cause the various diseases.  Making it more fluid or expanding on one of the diseases could give the reader a better grasp on the subject.  The diagram of the different mutations in the 3'-UTR was my favorite of all the pictures used.
In the end, I think you guys have a really good article and should be proud of the work you have done. Congrats!! We are almost at the end! Ekern529 (talk) 19:49, 13 April 2013 (UTC)
thread_title: External links

message: Overall, the article turned out really well with everything new added and edited.  The content of the subject is strong with good examples supporting the concepts and useful pictures to help with understanding some of the structures discussed.  Also, it is well written in a "wikificated" manner where laypeople will be able to understand the scientific information presented.  I also liked how you guys ended on an optimistic note with the future development section.
The first two paragraphs giving a brief summary and definition of 3'-UTR is very strong and gave a good overview of what is to come in the section below.  The second of the two seems a bit long for its purpose and could be edited down a bit since you repeat some of the information later in the other sections.  Also, I noticed that there was no citation in your first paragraph; I only comment on this because our ambassador said there should be one in every paragraph.
The physical characteristics section has good information, but the way it is presented seems choppy and a bit awkward at some times.  I think what may help with it is to add a little more information explaining some of the features instead of just jumping from one to the next or drawing conclusions prematurely.  One specific area I found a bit awkward and could a bit of work was when discussing the G+C percentage of the mRNA transcript.
The role in gene expression section to me was your strongest!  You guys have really good content here that is presented well and easy to understand.  Also, the examples of the different regulations really helped to prove the points and the pictures chosen helped as well.  My only suggestion is to add a picture of a stem-loop structure since it is discussed often and I feel like could be very useful as well to the laypeople to understand the mechanisms more.
The methods of study section needs a little more work.  Adding a couple sentences about the techniques of the mapping and sequencing would improve it so readers can understand how the results are determined and analyzed.  Also, the first sentence is a bit off-putting.  When you say the methods are tedious, then the reader will assume the paragraph will be as well and will not want to read the rest of it.  Mention that it can be tedious further in the paragraph and have a topic sentence stating the methods used to analyze the 3-UTRs.
The disease section has interesting information but I feel like its just a list of alterations that will cause the various diseases.  Making it more fluid or expanding on one of the diseases could give the reader a better grasp on the subject.  The diagram of the different mutations in the 3'-UTR was my favorite of all the pictures used.
In the end, I think you guys have a really good article and should be proud of the work you have done. Congrats!! We are almost at the end! Ekern529 (talk) 19:49, 13 April 2013 (UTC)
thread_title: Peer Review

message: I think poly(A) tails are made of AMP rather than adenine. The article says: "...addition of several hundred adenine residues called the poly(A) tail". Everybody understands the sentence but I think it is more correct with AMP.--Miguelferig (talk) 11:43, 11 March 2014 (UTC)
thread_title: Adenine / AMP / poly(A) tail

message: In the talk page of the UTR article, it was suggested to merge the 5', 3' and general UTR article into just one article. I think this would be very helpful, what do you think?  — Preceding unsigned comment added by Ilikelifesciences (talk • contribs) 16:47, 17 June 2016 (UTC)
thread_title: Merge with 5'UTR and general UTR article