Talk:Mir-194 microRNA precursor family

message: ===miR-194 Targets===
Gene         	EntrezID       	Sentences
CDH2         	EntrezID:1000  	25096247 microrna-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targeting cdh2 and igf1r. See 4 More Sentences
IGF1R        	EntrezID:3480  	25096247 microrna-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targeting cdh2 and igf1r. See 3 More Sentences
ITSN1        	EntrezID:16443 	24197061 microrna-194 (mir-194) regulates romk channel activity by targeting intersectin 1. See 1 More Sentence
ITSN1        	EntrezID:6453  	24197061 expression of mir-194 mimic also decreased the translation of exogenous itsn1 in the cells transfected with the itsn1 containing 3'utr but not with 3'utr-free itsn1 See 2 More Sentences
NR2F2        	EntrezID:386585	25412310 microrna-194 reciprocally stimulates osteogenesis and inhibits adipogenesis via regulating coup-tfii expression. See 2 More Sentences
NR2F2        	EntrezID:7026  	25800782 we showed evidence that hnf4gamma (upregulated in intestinal metaplasia) is targeted by mir-30 and that mir-194 targets a known co-regulator of hnf4 activity, nr2f2 (downregulated in intestinal metaplasia). See 1 More Sentence
BMI1         	EntrezID:648   	21851624 microrna-194 inhibits epithelial to mesenchymal transition of endometrial cancer  cells by targeting oncogene bmi-1. See 2 More Sentences
RBX1         	EntrezID:9978  	25412959 mir-194 targets rbx1 gene to modulate proliferation and migration of gastric cancer cells. See 2 More Sentences
CDKN1A       	EntrezID:1026  	22102710 mir-20a/b and mir-194 target cdkn1a and socs2 in follicular lymphoma, potentially contributing to tumor cell proliferation and survival. See 1 More Sentence
E2F1         	EntrezID:1869  	23213373 on the other hand, spherical cell shape-induced mir-194 and mir-320c would directly downregulate slc7a5 and e2f1 gene expression, respectively, which  are both related to malignancy. See 1 More Sentence
FOXM1        	EntrezID:2305  	24748184 microrna-194 inhibits the epithelial-mesenchymal transition in gastric cancer cells by targeting foxm1. See 1 More Sentence
FZD6         	EntrezID:14368 	21887698 mir-194 also targets human fzd6 and expression of mir-194 and fzd6 are inversely correlated in a mouse model of hepatocellular carcinoma (dgcr8(flox/flox) p53(flox/flox) x alb-cre). See 1 More Sentence
MECP2        	EntrezID:29386 	17347136 further, irradiation significantly altered expression of mir-194, a mirna putatively targeting both dna methyltransferase-3a and mecp2. See 1 More Sentence
RAC1         	EntrezID:363875	19892940 we conclude that both mirna-150 and mirna-194 inhibit hsc activation and ecm production, at least in part, via inhibition of c-myb and rac 1 expression. See 1 More Sentence
RUNX2        	EntrezID:12393 	25797619 taken together, our data suggest that mir-194 regulates osteoblast differentiation through modulating stat1-mediated runx2 nuclear translocation. See 1 More Sentence
SLC7A5       	EntrezID:8140  	23213373 on the other hand, spherical cell shape-induced mir-194 and mir-320c would directly downregulate slc7a5 and e2f1 gene expression, respectively, which  are both related to malignancy. See 1 More Sentence
SOCS2        	EntrezID:8835  	22102710 mir-20a/b and mir-194 target cdkn1a and socs2 in follicular lymphoma, potentially contributing to tumor cell proliferation and survival. See 1 More Sentence
SOX5         	EntrezID:6660  	22396742 mir-194 regulates chondrogenic differentiation of human adipose-derived stem cells by targeting sox5. See 1 More Sentence
STAT1        	EntrezID:20846 	25797619 microrna-194 promotes osteoblast differentiation via downregulating stat1. See 1 More Sentence
TLN2         	EntrezID:83660 	22829924 increased mir-194 expression markedly reduced levels of the cytoskeletal protein  talin2 and specifically inhibited luciferase reporter activity of a talin2 wild-type 3'-untranslated region, but not that of a mutant reporter, indicating that talin2 is a direct downstream target of mir-194. See 1 More Sentence
VIM          	EntrezID:7431  	21851624 ectopic expression of mir-194 in ec cells induced a mesenchymal to epithelial transition (met) by restoring e-cadherin, reducing vimentin expression, and inhibiting cell invasion in vitro. See 1 More Sentence
CD81 receptor	EntrezID:NA    	25218426 mir-194 is a hepatocyte gate keeper hindering hcv entry through targeting cd81 receptor. See 8 More Sentences
===miR-194 and Disease===
Disease                          	Type               	Sentences
DOID:3571: liver cancer          	MARKER             	20979124  mir-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice. See 1 More Sentence
DOID:5758: malignant mesenchymoma	INVOLVED IN DISEASE	21851624  ectopic expression of mir-194 in ec cells induced a mesenchymal to epithelial transition ( met ) by restoring e-cadherin , reducing vimentin expression , and inhibiting cell invasion in_vitro. See 1 More Sentence
Carighi (talk) 13:36, 5 January 2016 (UTC)
thread_title:  miR-194 information from text mining 

message: Disease                          	Type               	Sentences
DOID:3571: liver cancer          	MARKER             	20979124  mir-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice. See 1 More Sentence
DOID:5758: malignant mesenchymoma	INVOLVED IN DISEASE	21851624  ectopic expression of mir-194 in ec cells induced a mesenchymal to epithelial transition ( met ) by restoring e-cadherin , reducing vimentin expression , and inhibiting cell invasion in_vitro. See 1 More Sentence
Carighi (talk) 13:36, 5 January 2016 (UTC)
thread_title: miR-194 and Disease