Talk:Ephedrine

message: *User 155.245.123.4 decided to add a whole load of stuff to the sidebar which doesn't seem verifiable to me. Side effects of ephedrine apparently include:
"Increased thoughts
tingling sensations (positive)
plesurable goosebumps
massive increase in music appreciation
full stomach feeling (erradicates your appetite
increase cognition
[...] happiness
intense euphoria
increase cognition speed
increase in creative ideas"
I've not ever heard of any of these side effects... "massive increase in music appreciation"? Sounds more like cannabis to me. Thoughts?
*Update Well, nobody's commented on this so I'm going to revert the above changes to something sensible. --henryaj 17:35, 19 February 2006 (UTC)
replies: text: Dopamine levels?  No.  Serotonin might be related to euphoria.  Perhaps endorphins.  But dopamine does not produce pleasure.  As for ephedrine's effects people must be taking crazy doses to get all those enumerated above.  Listed study about music and dopamine in the brains of rats makes no mention of pleasure, only improvements in blood pressure.  — Preceding unsigned comment added by 102.65.54.41 (talk) 16:55, 8 June 2021 (UTC)
thread_title: New effects

message: The old one was ok, but I changed it for a differently designed molecule. 
The current one in use (the one I just made):
Image:Ephedrine.PNG
The old one:
They are the same molecule (obviously), but the old one looks much different. The old one would due just fine, but the one I just made (and used to replace the old one) is more visually related to other phenethylamine articles. See amphetamine, methamphetamine, cathinone, methcathinone, etc to see what I am talking about. This is the preferred way to look at these molecules, as it makes more visual sense when comparing them. I am going to go through some other articles that are similarly visually confusing, and create more molecule pictures that will make more visual sense when comparing certain chemicals (like say, comparing ephedrine to methcathinone), See?.--Ddhix 2002 19:32, 7 March 2006 (UTC)
thread_title:  Changed the Molecule Picture 

message: This article doesn't explain the effects of the substance on the body in plain language.  Ephedra is described as stimulating the brain, increasing heart rate, causing nervousness, constricting blood vessels, and expanding bronchial tubes. Are these effects attributable to ephedrine? -- Beland 17:21, 3 June 2006 (UTC)
thread_title:  Effects 

message: While the article states that ephedrine is legal in the US, this publication from the DEA seems to suggest otherwise (http://www.usdoj.gov/dea/pubs/abuse/2-chem.htm).  The listed threshold for ephedrine and "salts, optical isomers, and salts of optical isomers" is 0kg for domestic use.  The page has not been updated since 2001.  Can anyone provide more info?--24.16.148.75 16:14, 25 June 2006 (UTC)
replies: text: True we should also be refrencing the international commuminity. I am not sure wikipedia just translates the same article throughout all languages it serves. If it did I can imagine alot of bored people worldwide on this and many many articles. To get to the point of legality though someone should update the new legislature (I cant find but heard on the news?...strange but I cant seem to find it in search engines, perhaps someone else can) that Ephedrine's United States position has just changed to legally 10 MG of ephedra alkoloids per dose etc etc. I cant seem to find this but sure enough it was on the news! My informant didnt bother to record it for me since I have been a regular ephedrine user since I lost 86 pounds with a personal trainer and dietician in 1996 before the ban was mucked up by the supreme court. My local dealer (completly legal) and pharmacudical company I purchase from also confirms this but I cant get documentation to show for it. Also there are quite a few conspiracy theories to this drug that should be entered into the article regarding the possibility of pharmaceudical intent to monolpolize the drug because of its effectivness that should also be invoked for proper article faction. -Tabooooooooooo  —Preceding unsigned comment added by 64.121.0.16 (talk) 03:54, 17 August 2009 (UTC)
thread_title:  Legality 

message: The "Neurotoxicity of ephedrine" section of the article does not have any references at all. Take this sentence, for example:
Depletion of dopamine levels were roughly 25% with ephedrine, whereas dextroamphetamine reduced levels by nearly 75%.
That means absolutely nothing. It doesn't mention timescales, or permanance – nothing. In fact, the entire 'illicit use' section fails to cite sources. I'll put a notice up to this effect. --henryaj 18:40, 4 September 2006 (UTC)
replies: text: There is definitely no such thing like neurotoxiticy of neither ephedrine nor amphetamine. Adderall has been prescribed 37 million times in 4 years as you can read in the Adderall article. So please help to stop this fudding. I therefore would suggest to remove the whole section "Neurotoxiticy" --134.155.99.41 23:33, 2 May 2007 (UTC)
thread_title: Unreferenced sources

message: The article states: "In traditional Chinese medicines, the herb ma huang (Ephedra sinica) contains ephedrine as its principal active constituent."  I note that the site "Herbal Medicine Materia Medical" [] says:  
:"When studies were done using the whole plant, only a slight blood pressure elevation was found. This led to the discovery that pseudoephedrine, another one of the alkaloids present, slightly reduces both heart rate and lowers blood pressure, thus avoiding the side-effects that often accompany the use of ephedrine."  
It goes on to say that pseudoephedrine is just as effective as a bronchodilator.  In that case, would it not be correct to say that pseudoephedrine is yet another "principal active constituent" (since the whole plant is used to prepare ma huang)?  In that case, this sentence should perhaps be amended to include pseudoephedrine?  As I am only checking sources myself, I have no ax to grind here, but I would like to know the facts, unbiased by either side of any sort of debate.  (I do note that the Wiki article on pseudoephedrine does confirm that its source originally was indeed ma huang although it may be synthetically produced now.)  NaySay 15:17, 6 July 2007 (UTC)
thread_title:  pseudoephedrine? 

message: Is Ethedrine the same drug? I've found this spelling in a UK book so is/was this the spelling in the UK??  Could someone please clarify, thanks. Malick78 (talk) 10:03, 27 July 2008 (UTC)
replies: text: It should be ethamphetamine, I believe, if you follow the naming system. Mephedrone >> Ephedrone, Methedrine >> Ethedrine.  Enix150 (talk) 00:00, 7 May 2014 (UTC)
thread_title: Ethedrine?

message: Would such a list be useful added into this article? Or do you think adding such a list would be unethical?
Greggor88 (talk) 03:43, 1 March 2009 (UTC)
thread_title:  List of medications that still use Ephedrine or Pseudoephedrine 

message: This article states the rarity of certain side effects with no citation in many places.  I think that it may have been compromised by somebody who either sells or is a fan of ephedra.24.65.95.239 (talk) 02:47, 27 May 2009 (UTC)
thread_title:  Bias 

message: Some areas of the US describe Crystal Meth production as "epidemic", and ephedrine is a core component to that illegal drug.  I could find no reference to this anywhere in the article.Jonny Quick (talk) 05:16, 9 October 2011 (UTC)
replies: text: you can make "crystal meth" from different substances with different method. Ephedrine is just one way to make it and not a key substance. Large scale "crystal meth" production is done with P2P and nitroethane not ephedrine. You can find this information in pharmaceutical and medical literature.--DerElektriker (talk) 09:58, 27 February 2017 (UTC)

text: I have read that in Afghanistan methamphetamine production (mostly for export) has recently (unsure of year) switched largely over to ephedrine sourced from ephedra sinica, since it is a native plant (easily grown?), rather than using 'expensive imported pharmaceuticals' (pseudoephedrine) as a source material, for cost and availability reasons. I could not point you to the source though. It may have been somewhere on Wikipedia or in some news source. 2603:6011:1D00:2C49:314E:CE39:BF6B:B9E7 (talk) 03:58, 16 November 2022 (UTC)
thread_title:  Critical Ingredient in Crystal Meth 

message: Does anyone know why the "Compounds with decreasing α-receptor affinity" table is not working? Myoglobin (talk) 00:15, 20 December 2016 (UTC)
replies: text: it is a gallery not a table.  i played with it but couldn't figure it out.  the formatting is definitely messed up per :Template:Gallery and Help:Gallery tag. I cut it from there and pasted it here til it can be fixed.  Sandwiching with nowiki tags for now. 

| File:RS-Norephedrine.svg|Norephedrine
| File:RS-Ephedrine.svg|Ephedrine
| File:RS-N-Methylephedrine.svg|N-Methylephedrine

-- Jytdog (talk) 02:25, 20 December 2016 (UTC)

text: I figured it out, kind of, after coming across an example on another page. Couldn't figure out the overall caption or formatting, but cobbled something together, til somebody more competent fixes it fully. Jytdog (talk) 08:02, 20 December 2016 (UTC)
thread_title:  Mechanism of Action section not working 

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thread_title:  External links modified 

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*Added archive https://web.archive.org/web/20080921084346/http://www.ck10.uscourts.gov/opinions/05/05-4151.pdf to http://www.ck10.uscourts.gov/opinions/05/05-4151.pdf
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thread_title:  External links modified 

message: Why is the recreational use section about the synthesis of methamphetamine from ephedrine? Shouldn't it be about the recreational use of ephedrine? PlasmidPhononKid (talk) 05:27, 4 October 2020 (UTC)
replies: text: i second that 2603:6011:1D00:2C49:314E:CE39:BF6B:B9E7 (talk) 03:59, 16 November 2022 (UTC)
thread_title:  Recreational use