Talk:Reye syndrome

message: There's a statement about the possibility that acetaminophen is a larger risk factor than aspirin. Normally, I would add a "citation needed" but there is a citation -- to an article that does not make that claim in the first place. I'm not sure what the right way is to clean this up. 
The article claims that 1% of cases are correlated with aspirin consumption, only 1% of aspirin sales are for pediatric use, acetaminophen is the predominant pediatric medicine, and 6% of cases correlate with acetaminophen use. Although the article doesn't say what percentage of patients use acetaminophen overall, and the implication is that it's well over 6% (thus making the correlation with acetaminophen lower than with aspirin), it simply doesn't say one way or the other. I'm not trying to debate whether there's a link between either or neither of these, but there's no citation here. The article says nothing and implies nothing about the percentage of patients with and without the syndrome who use aspirin vs acetaminophen.Hagrinas (talk) 15:51, 21 March 2012 (UTC)
thread_title:  acetaminophen 

message: During my recovery from the flu, I've been applying salicylic acid topically as an acne medication. Yesterday, I had nausea, and two days ago, I threw up. At first I thought that these were only symptoms of the flu, but now that I've learned the link between sal. acid and Reye's syndrome, I think I might have it. Is there a 100% certainty? I mean, if you take salicylic acid while recovering from the flu, you WILL get Reye's syndrome?
:Short answer is no.  If you are concerned about your health I would seek treatment from a physician.  ChillyMD (talk) 20:50, 28 January 2009 (UTC)
replies: text: Slightly less short answer is that this is a forum about the article's content, not a forum for medical help. I appreciate that you have a legitimate need for information, but I'm simply stating the purpose of the Talk section. Hagrinas (talk) 15:54, 21 March 2012 (UTC)
thread_title: Someone help me

message: First of all, there are five stages, not two. Also, the symptoms are vague and nonspecific. I'll get this section cleaned up in a jiffity when I have time. Right now is not a good time, at least not for me.
Freddie 00:00, 17 March 2006 (UTC)
replies: text: I'd like to see some information on normal times to progression. The reye's foundation says "it strikes quickly" but there is no information on how long the various stages normally last before moving on to the next one. We don't really know if this is a disease that will progress in a matter of hours, days, weeks, months, years, etc.--Crossmr (talk) 12:09, 11 September 2008 (UTC)
thread_title:  Cleanup Required 

message: When I was a student at a tertiary neuroological centre, I was taught that Reye's syndrome is one of a family of mitochondrial diseases (mitochondropathies), which explains its multi-system nature and its predominant effects on liver and brain. Unfortunately this now lies well outside my field of expertise. Anyone elucidate? Thanks. Preacherdoc 13:57, 26 July 2006 (UTC)
replies: text:  These links mention how a virus might be causative, but doesn't give any hypothesis regarding the possible method by which salicilates have an effect.  I'd love to hear some speculation. ThVa (talk) 19:51, 16 September 2008 (UTC)
thread_title:  Mitochondropathy? 

message: I've noticed that bottles of Pepto and its generic versions contain a warning about possibly causing Reye's Syndrome. Shouldn't this get a mention as well? BioTube 18:27, 9 September 2006 (UTC)
replies: text: Pepto Bismol (bismuth subsalicylate) contains a salicylate compound in it. Since this article already says that salicylates precipitate the syndrome, there's no need to mention Pepto here. --David Iberri (talk) 14:46, 15 February 2007 (UTC)
thread_title:  Pepto-Bismol Connection 

message: Currently, this symptom has links to fat and liver. Would it not be more logical for it to have a link to fatty liver, or is the fat in the liver caused by Reye's Syndrome not the same as fatty liver?
--PBurns 22:17, 9 October 2006 (UTC)
replies: text: Answered on user's Talk page. Fredil Yupigo What has Wikipedia become? 22:21, 14 October 2006 (UTC)
thread_title:  Fat in Liver 

message: The current wikipedia entry for Reye syndrome is biased against aspirin as a potential risk factor, and this view seems to contradict the prevailing consensus of the scientific community on the subject.  As a result, the entry has poor credibility, and should be edited.
:Right now it looks like the article merely states two sets of facts, one: that aspirin has a tenuous connection to Reye's according to many studies (and for that matter Reye's seems to be nebulous in nature), and two: that The official reccommendations haven't changed to reflect these studies since an initial reaction in the 80s.  —Preceding unsigned comment added by 75.73.70.113 (talk) 03:42, 28 February 2010 (UTC)
thread_title:  aspirin bias? 

message: How is the disease treated? Is the coma reversible? Jack Daw 18:45, 3 December 2006 (UTC)
thread_title:  Treatment 

message: This page is partially a copyvio, but much content is original (e.g. by myself). Would not support deletion. JFW | T@lk 14:48, 20 February 2007 (UTC)
replies: text: Upon closer inspection, the URL that Katka193 was concerned about leads to a Wikipedia mirror. That does not remove my concern that much of the text of this article is unwikified and potentially copied from another source. JFW | T@lk 08:24, 21 February 2007 (UTC)
thread_title:  Not entirely copyvio 

message: - Someone please use these facts (as taught to us in medical biochemistry) to update the page
- See 1983 study on this subject
- Marked by dicarboxylic aciduria
- During viral illness, stress hormones cause release of FA.
- Salicylic acid (aspirin) binds carriers for these FA's (carnitine/CoA)
- Build up of FA in mitochondria due to lack of carriers can lead to the dissolution of mitochondrial membranes and can even lead to cell destruction
- Hexanoyglycine is the big marker for detection of this disease
- Hexanogylcine results from glycine conjugation in an amide conjugation with the free fatty acid
- Any questions, please ask I will try to check this later.  —Preceding unsigned comment added by 66.49.47.34 (talk) 20:22, 23 November 2009 (UTC)
thread_title:  sorry not sure where to put this, just making my contribution 

message: These External links are no more:
* FDA Bulletin on Reye-Johnson Syndrome
* Reye's Syndrome website at Brigham and Women's Hospital
I tried searching the sites for displacement addresses, but just couldn't find them. I don't know what the editors had in mind when choosing these links, but perhaps one of these sites could stand as a substitution:
* "NINDS Reye's Syndrome Information Page"
National Institute of Neurological Disorders and Stroke
http://www.ninds.nih.gov/disorders/reyes_syndrome/reyes_syndrome.htm
* "Reye Syndrome"
MedlinePlus, U.S. National Library of Medicine, National Institutes of Health
http://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&query=reye+syndrome
* "The Diagnosis and Treatment of Reye's Syndrome"
NIH Consensus Development Program, U.S. Department of Health and Human Services, National Institutes of Health
http://consensus.nih.gov/1981/1981ReyesSyndrome030html.htm
Yours, Wordreader (talk) 03:40, 16 June 2012 (UTC)
thread_title:  Expired external links 

message: Formally, in the USA in professional research circles, it's Reye-Johnson Syndrome.
However, the popular name has three variations across the 'Net and two can even occur within a single site. Creditable sites, too.
REYE Syndrome: FDA, PubMed Health, American Journal of Public Health article, Western Journal of Medicine article, American Liver Foundation, National Institutes of Health, Medline Plus, Centers for Disease Control, Department of Health & Human Services, American Medial Association
REYES Syndrome: Medline Plus
REYE'S Syndrome: National Reye's Syndrome Foundation, National Institute of Neurological Disorders and Stroke, Mayo Clinic, Western Journal of Medicine article, National Institutes of Health, Medline Plus, Centers for Disease Control, American Medial Association
For further information, these items give a history of the discovery and naming of the condition:
"Tale of Triumph on Every Aspirin Bottle", The New York Times http://partners.nytimes.com/library/national/science/051199sci-doctor-reyes.html
"Reye's Syndrome; Because You Need to Know" National Reye's Syndrome Foundation, Inc. http://nrsfpublishing.org/sampler/sampler_RS_BYNTK.pdf
"REYE SYNDROME: The Decline of a Disease", Department of Health and Human Services, Public Health Service, Food and Drug Administration http://www.web-pub.com/library/brochure/reye-syd.html
All the best, Wordreader (talk) 05:25, 16 June 2012 (UTC)
replies: text:  The ICD-10 names it as Reye syndrome, and hence as WP:MEDMOS says we should I think we should follow suite. I'm moving this article, if you have a problem with it change it, I just can't be bothered waiting years for somebody to care about the name of this enough to talk to me. Fuse809 (talk) 08:34, 14 February 2014 (UTC)
thread_title:  The name of the condition -- the winner is.... 

message: The page mentions treatment, but says nothing about what it is...  TREKphiler any time you're ready, Uhura 20:36, 7 October 2015 (UTC)
thread_title:  Take a pill 

message: Bibliography
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Please explain? Doc James (talk · contribs · email) 13:14, 9 May 2018 (UTC)
thread_title: Not sure what this is for?