Talk:Traumatic brain injury

message: Sports Related Traumatic Brain Injuries is an orphan (no other articles link to it). Any ideas on integrating this material? ~KvnG 22:47, 24 March 2014 (UTC)
thread_title:  [[Sports Related Traumatic Brain Injuries]] 

message: ... might actually be good doi:10.1186/cc13835. JFW | T@lk 19:55, 28 April 2014 (UTC)
thread_title:  Therapeuic hypothermia 

message: All of this was inserted at Neurodevelopmental disorder, and is off-topic there.  I am copying it here in case anything can be incorporated here.  SandyGeorgia (Talk) 21:28, 27 February 2015 (UTC)
thread_title:  Moved 

message: I would like to add information to the section "Severity" about the age differences on severity or, perhaps, add a section about "pediatric TBI". It's important to mention about it because there are major differences that take place.
Here is information I'd like to be added: 
There are age differences for the effects of traumatic brain injury (TBI) in children due to changes in skull formation. Infants’ skulls are divided into eight separated bones, which can spread during TBI and decrease the cranial pressure and brain swelling. These bones normally fuse by two years of age. In contrast, children are more vulnerable during TBI than adolescents, because they have wider subarachnoid spaces with blood vessels, which can become damaged by the shearing forces.
Psychiatric disorders may worsen or develop de novo in a child following TBI. Statistically about 54% to 63% of children develop novel psychiatric disorders about 24 months after severe TBI, and 10% to 21% after mild or moderate TBI, the most common of which is changes in personality. The symptoms include affective instability, aggression, disinhibited behavior, apathy, and may last for 6 to 24 months on average. Other disorders that may arise are ADHD, PTSD, OCD, anxiety disorder, depressive disorder and mania. Most symptoms decrease between 12 to 24 months. The superior frontal lesions correlate with the type of outcome, but more importantly, subcortical network damage may affect the recovery due to the lesions in white matter tracts.
Studies show that children with severe TBI are affected in intellectual functioning, executive functioning (including speed processing and attention), and verbal immediate and delayed memory with some recovery during the first 2 years post-injury. Such children are at more risk for long term consequences of TBI, because of the crucial developmental stage at which recovery takes place. 
Ebuglo (talk) 16:48, 28 February 2015 (UTC)
replies: text: Hi, .  I've altered your post a bit to add PMIDs to your sources (I hope you don't mind).  Your final source, , is a primary study, so that sentence isn't cited according to WP:MEDRS, but the other sources are recent reviews.  I haven't checked your text, but will ping  and , who are better equipped to determine if the text can be added, and where.  Best regards, SandyGeorgia (Talk) 22:59, 28 February 2015 (UTC)
replies: text: Hi,  Thank you for checking PMIDs. Indeed, I didn't catch the mistake about the last article. Thus I have deleted the last sentence.  and  , please, let me know if that would be possible to incorporate my added content accordingly. Kind regards. — Preceding unsigned comment added by Ebuglo (talk • contribs) 15:07, March 2, 2015 Ebuglo (talk) 20:08, 2 March 2015 (UTC)
replies: text:  , you can sign your entries by adding four tildes ( ~~~~ ) after them; pinging other editors doesn't always work, and it doesn't work on unsigned entries.  I cannot add your proposed text as I don't have full journal access, and this is listed as (not sure it is) a Good Article, so I'd rather have  or  look at the proposed content.  SandyGeorgia (Talk) 15:31, 2 March 2015 (UTC)
replies: text: last paragraph is empty of content, pretty much. affected to what extent, in what kinds of injury?  thx. Jytdog (talk) 21:00, 2 March 2015 (UTC)

text: i think you are doing great; i should have said that i find the 1st 2 paragraphs fine. The third just doesn't say anything.  If you fix that i would support adding this to the article. Jytdog (talk) 18:46, 3 March 2015 (UTC)

text: Sorry for the delay. I'd say the sources are all very good. The current page doesn't distinguish between adults and children. I'd say a discussion about the longer-term outcomes from (M)TBI is highly relevant. Could you tell us where in the article (i.e. which sections) you would like to make these additions? JFW | T@lk 06:58, 4 March 2015 (UTC)
thread_title:  Semi-protected edit request on 28 February 2015 

message: Hi, 
I wonder if it'd be possible to add a link to the Headway - the brain injury association website in the external links section? It's www.headway.org.uk
We have a large library of information and offer help and support to people affected by brain injury in the UK. I notice there is another UK charitable organisation listed, the Children's Trust's Brain Injury Hub, so this will add our support for adults with a brain injury.  
Many thanks, 
Andrew
Headwayuk (talk) 10:47, 24 November 2015 (UTC)
replies: text: We typically have very few external links. Try DMOZ. Doc James (talk · contribs · email) 12:04, 24 November 2015 (UTC)
thread_title:  Adding to external links section 

message: Stuhoffphd65 (talk) 18:56, 1 August 2016 (UTC)
replies: text: Not done: please establish a consensus for this alteration before using the  template.  Seems arguable since it is reliably sourced.  Welcome to Wikipedia, and please remember to sign your posts at the end, not at the beginning.  Temporal Sunshine Paine  19:09, 7 August 2016 (UTC)
thread_title:  Semi-protected edit request on 1 August 2016 

message: One of the things that needs to be added to this article is what is known as Tau. When a violent brain injury occurs, there's a buildup of the protein, Tau, which negatively affects the brain. Tau is most commonly seen in Alzheimer's patients, so if an individual has suffered form a TBI, this buildup will increase as they age. This protein is present in many other neurodegeerative diseases, so that's how doctors are able to track the degradation of the brain after a TBI.
Tau is a protein that was first discovered in 1975 by Marc Kirschner at Princeton University and was produced through alternative splicing of a single gene called MAPT (microtubule-associated protein tau) (REF 1, 2015).
Tau proteins are mainly active in the distal portions of axons where they stabilize microtubules as well as providing flexibility. The proteins work together with a globular protein called tubulin to stabilize microtubules and aid the assembly of tubulin in the microtubules. Tau proteins achieve their control of microtubule stability through isoforms and phosphorylation (REF 2, 2013).
Tau has been associated with Alzheimer's disease and other neurodegenerative conditions. Under ordinary conditions, tau is essential to neuron health, but in Alzheimer's the protein aggregates into two abnormal forms: "neurofibrillary tangles," and collections of two, three, or four or more tau units known as "oligomers” (REF 3, 2016).
Hyperphosphorylation of tau proteins is what creates the neurofibrillary tangles by causing the helical and straight filaments to tangle. This contributes to the pathology of Alzheimer’s disease (REF 2, 2013). Tau oligomers, on the other hand, have been found to be very toxic to nerve cells. They are also thought to have an additional damaging property. When they come into contact with healthy tau proteins, they cause them to also clump together into oligomers, and so spread toxic tau oligomers to other parts of the brain.
Scientists have found that traumatic brain injuries also generate tau oligomers. The destructive protein assemblages form within four hours after injury and persist for at least two weeks. This is long enough to suggest that they might contribute to lasting brain damage (REF 2, 2013).
Researchers from the University of Texas Medical Branch have found that a substantial amount of Tau is enough to play an important role in the effects of traumatic brain injury. Those effects can include memory deficits, which have been recently shown by UTMB researchers to be induced by tau oligomers. Other long-term ramifications of TBI include seizures, and disruptions in the sleep-wake cycle (REF 3, 2016). 
References
1.	Mandelkow, E.-M., and E. Mandelkow. "Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration." Cold Spring Harbor Perspectives in Medicine 2.7 (2012).
2.	Krishnamurthy, S., Sengupta, U., Castillo-Carranza, D., Dr. Prough, D., Dr. Jackson, 
G., Dr. DeWitt, D. (2013). “From trauma to tau – researchers tie brain injury to toxic form of protein.” http://www.utmbhealth.com/wtn/Page.asp?PageID=WTN000831
3.	Gerson, J., Castillo-Carranza, D., Sengupta, U., Bodani, R., Prough, D., DeWitt, D. 
(2016). “Traumatic brain injury induces mental impairments using mechanisms linked with Alzheimer’s.” http://www.utmb.edu/newsroom/article10817.aspx
Emiemilyyy (talk) 23:38, 8 November 2016 (UTC)
replies: text: - Provide more WP:RS.The first two of your sources are inaccessible.Also have a look at WP:MEDPRI(they are gen. of a low and controversial quality.Aru@baska❯❯❯   Vanguard 16:44, 8 December 2016 (UTC)
thread_title:  Semi-protected edit request on 8 November 2016 

message: Critical care management doi:10.1016/S1474-4422(17)30118-7 JFW | T@lk 11:30, 11 May 2017 (UTC)
thread_title:  Lancet Neurol 

message: doi:10.1111/jth.15096 JFW | T@lk 15:55, 25 October 2020 (UTC)
thread_title:  Role of vWF 

message: I'm not sure the redirect from Permanent Brain Damage to Traumatic Brain Injury is correct. That's because - according to this article - the cause of a Traumatic Brain Injury is an "external force." However, one can achieve Permanent Brain Damage without application of force. For example, here is the story of a woman who drank a bottle of soy sauce during a failed attempt at body cleansing who achieved permanent brain damage. There was  no force required; just internet misinformation.
Jeffrey Walton  (talk) 02:55, 2 October 2021 (UTC)
replies: text: You're quite right, thanks for pointing this out. Redirected to Brain damage. Better late than never! delldot ∇. 12:46, 13 August 2022 (UTC)
thread_title:  Permanent Brain Damage redirect? 

message: The word "pterion" is linked, but not in its first appearance.  Please move the link from appearance #2 to appearance #1. 49.198.51.54 (talk) 11:52, 9 July 2022 (UTC)
thread_title:  Semi-protected edit request on 9 July 2022 

message: The cited sources of this article are quite old, and it appears not to have been updated since its creation There is a surfeit of seemingly copy-pasted how-to, and a lack of secondary or tertiary sources. A full rewrite would take much effort on the part of brave editors.--Quisqualis (talk) 00:12, 11 August 2022 (UTC)
replies: text: If you have time you are certainly welcome and encouraged to take a crack at it!  An entire rewrite is daunting but it'd be a good start to add newer references to the info that's still good (or update it if it's not), and remove the how to and other crud that's accumulated. Thanks for pointing out the need for improvement! delldot ∇. 12:41, 13 August 2022 (UTC)
thread_title:  Outdated article could use a rewrite 

message: The age group at highest risk for TBI is 15-25 due to sports, etc... Not old age 104.192.232.8 (talk) 12:20, 27 November 2022 (UTC)
thread_title:  Risk factors is not old age, but late teen young adult age 

message: — Assignment last updated by Guevarab1 (talk) 19:24, 14 March 2023 (UTC)
thread_title: Wiki Education assignment: English 102

message: In the article "Traumatic Brain Injury", under the topic chronic stage, I wanted to add a portion about occupational therapy and what we do in working with people with TBI. 
Chronic stage
Once medically stable, people may be transferred to a subacute rehabilitation unit of the medical center or to an independent rehabilitation hospital.[89] Rehabilitation aims to improve independent functioning at home and in society, and to help adapt to disabilities.[89] Rehabilitation has demonstrated its general effectiveness when conducted by a team of health professionals who specialize in head trauma.[120] As for any person with neurologic deficits, a multidisciplinary approach is key to optimizing outcome. Physiatrists or neurologists are likely to be the key medical staff involved, but depending on the person, doctors of other medical specialties may also be helpful. Allied health professions such as physiotherapy, speech and language therapy, cognitive rehabilitation therapy, and occupational therapy will be essential to assess function and design the rehabilitation activities for each person.[121] Treatment of neuropsychiatric symptoms such as emotional distress and clinical depression may involve mental health professionals such as therapists, psychologists, and psychiatrists, while neuropsychologists can help to evaluate and manage cognitive deficits.[89][122] Social workers, rehabilitation support personnel, nutritionists, therapeutic recreationists, and pharmacists are also important members of the TBI rehabilitation team.[121] After discharge from the inpatient rehabilitation treatment unit, care may be given on an outpatient basis. Community-based rehabilitation will be required for a high proportion of people, including vocational rehabilitation; this supportive employment matches job demands to the worker's abilities.[123] People with TBI who cannot live independently or with family may require care in supported living facilities such as group homes.[123] Respite care, including day centers and leisure facilities for disabled people, offers time off for caregivers, and activities for people with TBI.[123]
Pharmacological treatment can help to manage psychiatric or behavioral problems.[124] Medication is also used to control post-traumatic epilepsy; however the preventive use of anti-epileptics is not recommended.[125] In those cases where the person is bedridden due to a reduction of consciousness, has to remain in a wheelchair because of mobility problems, or has any other problem heavily impacting self-caring capacities, caregiving and nursing are critical. The most effective research documented intervention approach is the activation database guided EEG biofeedback approach, which has shown significant improvements in memory abilities of the TBI subject that are far superior than traditional approaches (strategies, computers, medication intervention). Gains of 2.61 standard deviations have been documented. The TBI's auditory memory ability was superior to the control group after the treatment.[64] Melissa Scotti Alvarado (talk) 20:58, 28 July 2023 (UTC)
replies: text: Not done for now: please establish a consensus for this alteration before using the  template. - FlightTime (open channel) 21:01, 28 July 2023 (UTC)
replies: text: This is a huge edit and will take some time to transition from academic writing to Wikipedia style. A lot of the resources look to meet WP:MEDRS from my perspective but it could use some tweaking to not sound promotional in nature- i.e "OTs are experts at..." . Would you consider doing a few practice edits on Wikipedia first to get experience and then gradually making edits to this article to improve the OT section? I think you need to make 10 edits over 4 days to get confirmed (see link below). Start by some copy editing on non-protected articles, find a secondary source and practice adding it with the correct template, etc, and it will help you get ready to improve this article. You can also review WP:MEDMOS, wikipedia's medical manual of style for appropriate headings and subheadings for this article. Here is what I found re criteria on how to be a confirmed editor  which would allow you to work incrementally on this article and not need permission (just work with the community to improve it and discuss challenges on the talk page) https://en.wikipedia.org/wiki/Wikipedia:User_access_levels#:~:text=Users%20are%20automatically%20promoted%20into,of%20age%20and%20500%20edits.  let me know if this makes sense or if I can help in any way! JenOttawa (talk) 23:48, 28 July 2023 (UTC)
thread_title:  Semi-protected edit request on 28 July 2023