lflage/wiki-talks huggingface dataset:
Talk:Long-chain-fatty-acid—CoA ligase

message: As the article's title indicates, this entry should be about an enzyme, acyl-CoA synthase, and not a gene... Can anyone please explain me this? Thank you very much
Tina says: The entry is about the acyl-CoA synthetase enzymes. The mention about the genes that encode the enzymes is only at the end of the page, under "Examples".  —Preceding unsigned comment added by 198.82.20.161 (talk) 18:57, 17 May 2011 (UTC)
thread_title:  Wrong title?? 

message: Should the mechanism  be removed? 
* I wonder about the name adenine triphosphate. Adenine is indeed the base, but ATP is a triphosphate of the nucleoside adenosine. 
* I was under the impression that a magnesium ion stabilizes the alpha phosphate's trigonal bipyramidal transition state in step one (not bonding with the other two phosphates). What has the research shown? Are side chains of the enzyme complimentary to these phosphates or is it really the Mg ion?
* Why does step 3 depict coenzyme A forming a bond with the phosphate? The next image depicts CoAS bonded to the acyl carbon?
* The final product is labeled "Produt"
* Must R always be long chain C-C bonds?
* Are these all completely reversible reactions?
* Are the formation and collapse of transition states separate steps? Is this mechanism really four unique steps or two steps with two transition states (or something else)?
Thanks, Vokesk (talk) 15:11, 27 April 2012 (UTC)
thread_title:  Mechanism image 
Template talk:Governors of Louisiana

message: We should not be adding Governor-elect to this Template. We should wait until the elected person actually becomes Governor. GoodDay 16:14, 7 November 2007 (UTC)
thread_title: Governoer-elect

message: I'd do it myself but have no idea how to program such a thing, but there needs to be an option to expand both sections, such as in the case of P. B. S. Pinchback, who served as both governor and lieutenant governor.  In that case, rather than run the same template twice with different sections expanded, we could just run the template once and expand both sections by default.  What do you think?  SchuminWeb (Talk) 02:48, 8 March 2009 (UTC)
replies: text: I gave it a shot, but like I said, I don't really know what I'm doing on this front.  SchuminWeb (Talk) 02:54, 8 March 2009 (UTC)
thread_title:  Ability to expand both sections? 

message: See the centralized discussion here. thank you. Frietjes (talk) 22:27, 10 February 2012 (UTC)
thread_title:  Inline style statements
Talk:Thymidylate synthase

message: The article uses synthase; the figure uses synthetase. If both are correct, the article should mention that. Palpalpalpal (talk) 08:40, 24 April 2008 (UTC)
replies: text: I t hink they are distinct enzymes and this article name Thymidylate synthase is wrong and it should be renamed/moved to Thymidylate synthetase - sadly that currently redirects to Thymidylate synthase.  Note there is already a Thymidylate synthase (FAD). - Rod57 (talk) 13:53, 21 September 2012 (UTC)
thread_title:  Synthase or synthetase? 

message: This molecule is a Synthase as it doesn't use ATP to catalyse the reaction. This must be corrected as it's often misunderstood. Synthase is also called a Ligase in english (Tough in french both old word exist and are valid).  —Preceding unsigned comment added by Enteris (talk • contribs) 13:37, 9 April 2010 (UTC)
thread_title:  Synthase 

message: "Thymidine is one of the nucleotides in DNA" is wrong but I cant see where to edit it.82.14.215.85 (talk) 15:43, 3 April 2019 (UTC)
thread_title: Nucleoside
Talk:Transcription factor Jun

message: In an oncology course I took a while back, we were told (anecdotally) that that name jun came from Japanese for seventeen, "juunana," courtesy of a Japanese graduate student who isolated the protein from avian sarcoma virus 17.  There's enough apocryphal molecular biology naming attributions out there that I'm hesitant to add this.  Can anyone confirm it? - J. Hengenius (talk) 15:18, 4 June 2008 (UTC)
thread_title: Untitled
Talk:Delhi P. Sunder Rajan

message: I've removed an old neutrality tag from this page that appears to have no active discussion per the instructions at Template:POV:
::This template is not meant to be a permanent resident on any article. Remove this template whenever:
::#There is consensus on the talkpage or the NPOV Noticeboard that the issue has been resolved
::#It is not clear what the neutrality issue is, and no satisfactory explanation has been given
::#In the absence of any discussion, or if the discussion has become dormant.
Since there's no evidence of ongoing discussion, I'm removing the tag for now. If discussion is continuing and I've failed to see it, however, please feel free to restore the template and continue to address the issues. Thanks to everybody working on this one! -- Khazar2 (talk) 13:42, 14 June 2013 (UTC)
thread_title:  removing POV tag with no active discussion per [[Template:POV]]
Talk:CXCR3

message: In some publications I have found CXCR3 is also a weak target for the chemokine ligand CCL21. This is particularly highlighted in CNS models:
http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=11307161&retmode=ref&cmd=prlinks  — Preceding unsigned comment added by Samsauma (talk • contribs) 18:43, 1 June 2011 (UTC)
thread_title: Untitled
Talk:Devadanapatti

message: This Town panchayat has 4 schools.One Higher Secondary School run by Tamilnadu Government.One Middle School run by Hindu management,one Primary school run by Church of South India and another Kallar Primary school run by TN government.  —Preceding unsigned comment added by 216.139.148.118 (talk) 17:54, 14 January 2010 (UTC)
Talk:Dhanushkodi

message: johny 19:00, 24 November 2018 (UTC)
thread_title:  Could someone add the meaning and significance of Dhanushkodi from a proper source? 

message: Danushkodi is metropolitan city rameshwaram cyclone came 49.37.213.172 (talk) 12:51, 19 April 2022 (UTC)
thread_title:  Dhanushkodi
Talk:Glutaminase

message: Does anyone know where glutaminase is localized in the cell? Is it soluble or membrane-bound? Where does the substrate come from (inside or outside the cell)? Where does the product go (inside or outside the cell)?  —Preceding unsigned comment added by 63.125.124.226 (talk) 15:58, 16 December 2008 (UTC)
thread_title:  Localization
Talk:Manteca Transit

message: a picture of an actual bus would be good.T ALK•QRC2006•¢ʘñ†®¡ß§ 00:39, 1 May 2007 (UTC)
thread_title: image
Talk:Doveton Corrie Protestant Schools Association

message: www.dovetonpast.com  —Preceding unsigned comment added by 61.16.174.50 (talk) 10:56, 3 June 2008 (UTC)

message: Do students find there is a bias toward religion and forcible conversion?  —Preceding unsigned comment added by 61.16.174.50 (talk) 10:57, 3 June 2008 (UTC)
thread_title:  Bias towards religion
Talk:Dusi, Tamil Nadu

message: English VinothkumarAravamuthan (talk) 03:16, 8 October 2019 (UTC)
thread_title:  Vino
Talk:6-Phosphogluconate dehydrogenase

message: At the moment the page is 'Phosphogluconate dehydrogenase' but 6-phosphogluconate dehydrogenase (now a redirect) seems better ? - Rod57 (talk) 19:48, 15 June 2016 (UTC)
replies: text:  I totally agree. Nicolas Gambardella (talk)  — Preceding undated comment added 16:46, 26 December 2020 (UTC)
thread_title:  Proposed rename to 6-phosphogluconate dehydrogenase
Talk:Transaldolase

message: This article is about the family of transaldolase enzymes while the intended scope of the transaldolase B article also appears to include the entire family, hence it would make sense to merge these two articles. The protein box in the transaldolase B article only contains links to the E. coli enzyme whereas the infoboxes in this article cover the entire family.  Boghog (talk) 07:35, 19 September 2010 (UTC)
thread_title:  Merger proposal
Talk:Edaikodu

message: Puthenchanthai is in Kanyakumari District Villavancode taluk. A small village shared by both Maruthancode &  Edaicode Panchayat in the state of Tamil Nadu, India
Assembly constituency : Vilavancode
assembly constituency                                                                 
Assembly MLA :S. Vijayadharani                                
Lok Sabha constituency :Kanyakumari
parliamentary constituency                                              
Parliament MP : Pon Radhakrishnan
Serpanch Name : Serpanch Name Puthenchanthai (talk) 10:10, 24 April 2017 (UTC)
thread_title:  Puthenchanthai
Talk:RET proto-oncogene

message: MEN2a and 2b are the CURRENT names, MEN 3 is outdated following the discovery that MEN2B was caused by a mutation to the same gene (met->thr mutation on RET).  I've changed the article accordingly.  —Preceding unsigned comment added by ChillyMD (talk • contribs) 13:53, 23 January 2009 (UTC)
thread_title: Formerly MEN2a/2b

message: Cabozantinib Improves Outcomes Over Erlotinib in Advanced NSCLC says cabozantinib is also an inhibitor of RET and ROS1. May explain good results in NSCLC. - Rod57 (talk) 11:59, 3 December 2016 (UTC)
thread_title:  As a drug target
Talk:Edappadi

message: Hello Everyone,
I did some edits to this article as most of the contents appeared before are copied from oher websites. Even though some of the contents looks promising, I didn't find any references from reliable sources. So, I need your ideas what to do in this situation?
Thank you.  — Preceding unsigned comment added by Mykeralatrip (talk • contribs) 23:50, 27 May 2022 (UTC)
thread_title:  Reliable sources are lacking for this article
Talk:Elampillai

message: The following coordinate fixes are needed for
—171.76.252.35 (talk) 16:34, 28 May 2014 (UTC)
replies: text: You haven't said what you think is erroneous, but I've made the coordinates in the article a bit more precise. Is that satisfactory? Deor (talk) 21:29, 28 May 2014 (UTC)
thread_title:  Coordinate error
Talk:Elayirampannai

message: 9°16'16.8"N 77°49'36.7"E
The following coordinate fixes are needed for 9°16'16.8"N 77°49'36.7"E
The co-ordinate mentioned in it is wrong
—M S Parthiban  — Preceding unsigned comment added by 49.37.217.144 (talk) 15:43, 13 November 2021 (UTC)
thread_title:  Coordinate error
Talk:Eruvadi

message: As you can see, I've removed the majority of the article. Wikipedia articles must be neutral—they cannot be used to praise a city, people's ancestors, the quality of the countryside, etc. Information should also be verified by reliable sources; I've kept some of the unsourced info, but we really do need references for what remains in the history section. Qwyrxian (talk) 13:12, 13 February 2013 (UTC)
replies: text: I have made some more clean up. Venkat TL (talk) 08:23, 8 September 2021 (UTC)
thread_title:  Article trimming
Talk:Carnitine palmitoyltransferase I

message: :Oppose proposed merge. --Arcadian 11:35, 11 June 2007 (UTC)
thread_title: Untitled

message: While I am not 'expert' I am not a complete novice either than found this article challenging.
Should 'Biological function' for example being moved higher up the article, since it is the thing that 'Joe Public' would be most interested in?
The diagrams appears to show the outer mitochondrial membrane as 'diffusible' and with an orange broken line.  Again it appears to show the inner mito membrane as solid blue.  An addition to the key (of the image) making this crystal clear and easy to read would be a major bonus to readability.  --Leopardtail (talk) 13:26, 25 March 2014 (UTC)
thread_title:  Biological function: Adaptations for 'lay readers'
Talk:Protein kinase C zeta type

message: For future reference, I just wanted to note here that there are a couple phrases in this article that were written by , who is also the author of . So in case anyone ever suspects it, it's not actually plaigarism. Cheers, David Iberri (talk) 20:21, 11 May 2007 (UTC)
thread_title: Not plaigarism

message: : Thus PKMζ is both necessary and sufficient for maintaining LTP.
I don't follow how the preceding text demonstrates sufficiency.  Surely there are other chemicals there that have not yet been knocked out. MaxEnt (talk) 15:21, 7 April 2009 (UTC)
replies: text: Infusing PKMz into postsynaptic cells produces the same changes that underlie the maintenance phase of late LTP. My understanding is that if PKMz is applied, no upstream molecules appear to be needed (eg, CaMKII, PKA, etc.), which demonstrates sufficiency. --David Iberri (talk) 00:09, 6 August 2009 (UTC)
thread_title: Sufficient
Talk:IAR-93 Vultur

message: I think this page should be merged with J-22 Orao page - it's the same aircraft after all.  —Preceding unsigned comment added by 147.91.1.41 (talk) 13:28, 22 November 2007 (UTC)
thread_title: Untitled

message: The figure must be wrong, it is way to high.--82.76.8.11 (talk) 17:17, 27 December 2007 (UTC)
thread_title: Useful load
Talk:KLRA1

message: Not sure if I can delete it, but page Klra1 isn‘t necessary, it could be just Klra or redirected to Ly49.
Explanation: I canceled redirection from page Ly49 to Klra1, because they are not the same. Ly49 is family of proteins, which are coded by gene cluster named Klra, e.g. Klra1 is gene coding Ly49A. Yes, there are two gene nomenclature systems – Klra and Ly49 like the proteins, but former page Klra1 talked about proteins.  — Preceding unsigned comment added by PavlinaJancova (talk • contribs) 18:16, 30 June 2019 (UTC)
thread_title:  Change June 2019
Talk:Myelin protein zero

message: I'd like to add to more information to this article. I propose the following changes to improve the Myelin Protein Zero article:
-The article currently has two information sections: Function and Interactions. I'd like to improve the article by adding more specific sections. I'd like to add a:
* Structure section discussing the structure of myelin protein zero
* Mutation section: discussing the effects of myelin protein zero mutations 
* Association with Charcot-Marie Tooth Disease and Derjerine -Sottas Disease section: discussing how myelin protein zero plays a role in these two diseases
I'd also like to add more information to the function section. Specifically:
* How myelin protein zero expression is induced by axon signals
* How myelin protein zero is responsible for keeping the myelin sheaths together by self adhering to other myelin protein zeros
I'd also like to add more information to the interactions sections. Specifically:
* Myelin depends on homophilic interactions with other myelin protein zero molecules
* How the cytoplastmic domain of myelin protein zero folds into secondary structures
* How myelin protein zero interacts with lipids and tryptophan to adhere to the neuron membrane
If you have any thoughts on this, I'd really appreciate feedback or suggestions.  
 Naironfire (talk) 05:33, 10 May 2018 (UTC)
thread_title:  Proposal to edit myelin protein zero article
Talk:Glutamate carboxypeptidase II

message: I've found on the web that there is a second enzyme, very similar to GCP II, called GCP III (OMIM 609020). Does it mean that there are two enzymes degrading NAAG to NAA and glutamate? If so the text should be changed accordingly. CopperKettle 15:31, 24 July 2007 (UTC)
thread_title:  One or two NAAG peptidases? (GCP II, GCP III) 

message: Does anyone else agree that this chemdraw looks kind of sloppy?  I just created
a better version that doesn't show the aspartyl sidechain bumping into glutamyl amine, 
but i'm having troubler uploading it and replacing the old one.   Hopefully i'll figure
out soon, or someone else will fix this problem.  otherwise this is a pretty solid page
on GPCII.  —Preceding unsigned comment added by Marcxanderson (talk • contribs) 08:09, 6 September 2007 (UTC)
thread_title:  chemdraw of NAAG proteolysis 

message: I believe that imaging applications (PET/CT) have improved since that part was written. Helpful would be some experience about thresholds for the identification of tumors (e.g. expressed in PSA-values)  Meerwind7  12:21, 13 Jan 2015 (UTC)
thread_title:  Update on imaging 

message: I propose that Prostate_specific_membrane_antigen be merged into Glutamate carboxypeptidase II. Because... seriously.
: Completed. LT90001 (talk) 13:08, 26 August 2013 (UTC)
thread_title:  Merger proposal 

message: This molecule was just involved in the characterization of a new salivary gland located in the pharynx. https://www.sciencedirect.com/science/article/pii/S0167814020308094?fbclid=IwAR0nA8sreP1haUBaqnntkwNw1TxwncpJLFviuDGRwv_vJ7XdVR1EM2gHE5M#b0080
UWM.AP.Endo (talk) 02:48, 20 October 2020 (UTC)
thread_title:  New paper --> new organ! 

message: — Assignment last updated by W1i2k3i4p5e6d (talk) 19:41, 27 April 2024 (UTC)
thread_title: Wiki Education assignment: CHEM 378
Talk:Beta-ketoacyl-ACP synthase

message: "The enolate tautomerizes to a carbanion that attacks the thioester of the acetyl-enzyme complex." In my opinion, the enolate and the carbanion rather represent two resonance structures of the very same molecule, while tautomerisation would imply them being two structural isomers, which is not the case - or do I miss something?
--Neonoia (talk) 10:00, 25 April 2020 (UTC)
thread_title:  Tautomerisation?
Talk:First Judicial District of Pennsylvania

message: I wrote this article way back when, always looking input and revisions.  Expansions would be especially appreciated. RegBarc 00:26, 27 April 2007 (UTC)
thread_title: Introduction
Talk:Gudalur, Theni

message: An interesting fact I observed is that Cumbum, Tamil Nadu and Gudalur are towns in Theni district of Tamil Nadu state. In the neighbouring state of Andhra Pradesh there are neighbouring towns named Cumbum, Andhra Pradesh and Giddaluru. Interestingly, Theni district has a large population of migrants from Andhra Pradesh state. Could there be a co-relation? --AltruismTo talk 07:12, 26 July 2007 (UTC)
thread_title:  An interesting observation 

message: Gudalur have couple major government banks located STATE BANK OF INDIA,CANARA BANK,KARUR VYSYA BANK.  — Preceding unsigned comment added by 144.36.228.67 (talk) 11:48, 26 June 2012 (UTC)
thread_title:  Banks
Talk:H. S. S. Lawrence

message: This entire article appears to have but one source, "My Life and Times (the hand of God)", by none other than the subject of the article itself. Almost all of the article is non notable, anecdotal, and unfit for inclusion in an encyclopedia. In addition the images used all appear to be in violation, as they do not appear to be the work of the Wikipedian who has claimed that they are. Weakopedia (talk) 21:40, 19 February 2011 (UTC)
thread_title:  Non notable content 
Talk:Harur

message: How can resolve this Issue?  — Preceding unsigned comment added by Vinoth88 (talk • contribs) 04:48, 6 September 2013 (UTC)
thread_title: Need additional Citations for verification. How to resolve that?
Talk:Ilaiyangudi

message: Hi @venkatershlvr. Please do not add ATM and BANK details. They are not necessary. Please see the order given at Wikipedia:WikiProject Indian cities and Wikipedia:WikiProject Cities/Settlements: Article structure.Do not add unnecessary table or information. Please add a Citation Venkat TL (talk) 17:26, 22 October 2021 (UTC)
thread_title:  ATM and table
Talk:Pine Ridge High School

message: *Ben De La Cruz - Football - Class of 2009 - Accepted a scholarship to play from Bethune-Cookman University. After being a Wildcat for two seasons, he transferred to Eastern Kentucky University.
*Peter Peppers - Football - Class of 2010 - Accepted a scholarship from Evangel University.
*John Bennett - Football -Class of 2010 - Accepted a scholarship from St. Olaf College.
*Austin Leep - Football - Class of 2012 - Accepted a scholarship from University of Charleston WV.
I removed the entire above section since none of the atheletes meet notability requirements. Please don't restore them without evidence of notability and attendance. Accepting a scholarship does not make them notable. A wikipedia article for each or reliable sources are needed. Meters (talk) 00:02, 11 September 2012 (UTC)
thread_title:  "Notable" Athletes
Category talk:Light-weight Linux distributions

message: So I added one. Fits on a standard MiniCD, or 210mb or smaller. 81.197.43.229 (talk) 18:34, 26 February 2008 (UTC)
replies: text: The Mini Linux article now redirects to Lightweight Linux distribution.  Part of the reason for the name change is the ambiguity in the inclusion criteria.  70.247.172.237 (talk) 23:37, 2 January 2011 (UTC)
thread_title:  No standard for inclusion 

message: MenuetOS doesn't belong in a list of Linux distrubutions, since it isn't Linux. Change the article name to be properly inclusive, or remove the entry for a Mini system which isn't Linux.  — Preceding unsigned comment added by 12.203.180.244 (talk) 02:53, 9 June 2016 (UTC)
thread_title:  Remove MenuetOS
Talk:Ray E. Porter

message: He was my great Grandfather
: Please add to the main page and let us know more about him!!! Mfields1 00:54, 27 April 2007 (UTC)
replies: text: Sure. My Username is Dnorthington3 and I posted his Biographic Sketch on the page. All of the Information underneath the title "From..." provided by Dnorthington3 was provided by me, including his medals and promotions sections.Dnorthington3 (talk) 00:30, 25 February 2008 (UTC)
thread_title: Untitled
Talk:Jayankondam

message: JANAKIRAMAN JKM   —Preceding unsigned comment added by Lawrence6l (talk • contribs) 14:02, 28 August 2009 (UTC)
thread_title:  JOHNNY 
Talk:Kadambur

message: Kadambur
From Wikipedia, the free encyclopedia
Kadambur
—  village  —
 
Kadambur
Location of Kadambur
in Tamil Nadu and India
Coordinates	8.98°N 77.87°ECoordinates: 8.98°N 77.87°E
Country	 India
State	Tamil Nadu
District(s)	Thoothukudi
Population	4,379 (2001)
Time zone	IST (UTC+5:30)
Area
• Elevation
• 84 metres (276 ft)
Kadambur (Tamil: கடம்பூர்) is a panchayat town in Kovilpatti taluk of the Thoothukudi district in the Indian state of Tamil Nadu. The temples in and around Kadambur portray the authentic Chola art and architecture.
Contents [hide]
1 Geography
2 Demographics
3 Schools
4 Temples
5 Transport
6 References
7 External links
[edit]Geography
Kadambur is located at 8.98°N 77.87°E[1]. It has an average elevation of 84 metres (275 feet).
[edit]Demographics
As of 2001 India census[2], Kadambur had a population of 4379. Males constitute 49% of the population and females 51%. Kadambur has an average literacy rate of 68%, higher than the national average of 59.5%: male literacy is 76%, and female literacy is 61%. In Kadambur, 10% of the population is under 6 years of age..And kadambur is famous for boli a sweet snack... There is also a kadambur in Cuddalore dist called melakadamburfamous in Devaram and a rare piece of master architecture temple known as Karakoil
[edit]Schools
Sandrore Middle School (Saraswathi Vidyalaya)
George High School
Hindu Nadar Higher Secondary School
[edit]Temples
Ambigai Parasakthi Sri Mariamman Temple (Kadambur Hindu Nadar Uravinmurai Sankam)
Ambigai Sri Kaliamman Temple (Kadambur Hindu Nadar Uravinmurai Sankam)
Lord Siva Temple - Sri Udayanambesvar
Periya karuppa samy temple
[edit]Transport
Kadambur Railway Station lies on the Kovilpatti – Tirunelveli railway line of the Southern Railway Zone of Indian Railways. Tuticorin Airport is the nearest domestic airport. Regular buses run from Kadambur bus station to Tuticorin, Kovilpatti, Idaiseval and several other places.  —Preceding unsigned comment added by 122.174.77.29 (talk) 09:35, 23 January 2011 (UTC)
thread_title:  Kalirajan 

message: I Love My Native  —Preceding unsigned comment added by 117.242.213.18 (talk) 16:08, 25 January 2011 (UTC)
thread_title:  B.Kali rajan
Talk:Flying claws

message: Hey I feel there needs to be WAAAAAY more stuff about Flying Claws then I know about.  So you martial arts experts out there tell me about this. Monkeywrenchned 00:34, 27 April 2007 (UTC)
thread_title:  Needs more stuff 

message: An image, drawing or photo, would also be beneficial. HairyWombat (talk) 00:17, 22 June 2010 (UTC)
thread_title:  Needs an image 

message: http://www.wle.com/products/WGL322.html
The image on the above site suggests the article is factually incorrect. Rhialto (talk) 14:03, 28 October 2012 (UTC)
thread_title:  Fact checking needed