Talk:DNA separation by silica adsorption

message: I am creating this article for a class project.  Please note any changes you would like to see here rather than editing the page directly until 12/15/2006.  Thanks!  (The preceding unsigned comment was posted by User:ReginaSophia at 18:50, 3 December 2006.)
: Thanks Regina. This article is part of a WP:SUP student project on Downstream_processing at Cornell University. It is slated for scientific peer review by the user's classmates and instructor over the next two weeks and will be finalized (for the purposes of the class) by 15 Dec 2006. If you would like to help, please hold off from the normal "bold editing" process until after December 15, and instead leave comments and suggestions for User:ReginaSophia here on the article discussion page. Your thoughtful review will be very much appreciated! 
Jean Hunter, instructor, BEE 464 susato 17:41, 4 December 2006 (UTC)
thread_title:  Student Project, December 4-15, 2006 

message: Hey Regina, I have a few comments to make.  First, theres a few places where the grammar needs to be polished.  Phrases including "meet the rises demand," "rapid results, in field applications, low costs...", "these decrease in surface charge leads to," and "theses molecules."  That aside, I have two questions that arise when reading.  First, I spent a good part of my summer doing mini-preps and was simply curious if you know how the cells are lysed after they're put onto the chip.  Also, I'm not sure I completely understand why silica is used as opposed to other molecules.  I imagine it doesnt necessarily have much to do with the charge since its negative and so is DNA.  Is there anything in particular that makes the DNA adsorb to the silica better than positively charged molecules running through the chip?  Overall though, I liked the organization in the article.  It flows well and gets some good info across.  Good job.
Steve Lund 07:28, 5 December 2006 (UTC)
thread_title: Reviews

message: Thanks to everyone who reviewed my article.  I have made all of the grammatical corrections that you suggested.  In addition, I've added things like the solutions that may be used and the types of samples that are loaded.  Hopefully, I've also clarified the entive process with my brief overview at the beginning.  As for adding GuSCN, were you using this for this exact method?  I will stick to the publish solutions that I have until I hear back from you.
Thanks again, ReginaSophia 01:13, 15 December 2006 (UTC)
thread_title: Thanks to all the Reviewers

message: Isn't this basically a solid phase extraction method? --Kupirijo 03:59, 2 November 2007 (UTC)
thread_title:  Solid phase extraction 

message: The description of this approach, focusing as it does only on a chip-based automated process, seems too specific for the generic page name.  DNA separation by silica adsorption equally describes the use of silica beads, membranes and columns that are much more commonly utilized applications than this chip-based approach.  As far as I can tell, these more common alternative forms of silica adsorption are not given a detailed description anywhere (there is a generic description of one option at Spin column-based nucleic acid purification, and this page would seem to be the place.  Indeed, I thought it might be a push-page for a particular proprietary technology until I saw its history here as a student project.  69.166.47.99 (talk) 18:17, 10 March 2016 (UTC)
replies: text: I totally agree with that assessment and came to this talk page to write basically the same thing. I've tried to clean-up the article a bit so it doesn't focus on chip-based DNA separation, which is rarely used compared to the other silica adsorption technologies like columns or beads or plain-old silica resin. Nosferattus (talk) 01:03, 4 July 2022 (UTC)
thread_title:  Too application-specific?