Talk:Tetrahydrocannabinol

message: To clarify concerning the revisions mentioning that states in the United States allow use of THC in the form of cannibis, it is not necessary to include any cite to the FDA, because the article says that the "States" allow it with certain exceptions of the few states that don't- it does not say the U.S. federal government allows it. The FDA is NOT a "state" agency so there would not be any citation to the FDA as a source. The article was amended to clarify that the federal government (e.g. the FDA) maintains it as a schedule I substance. It is apparent that Zefr's undo revison while well meaning, rests on misapprehension of the edit. 2600:8804:7100:4000:5D4B:71DA:2CC1:208F (talk) 03:09, 10 December 2022 (UTC)
thread_title:  December 2022 Revisions concerning medical use of THC in the United States 

message: Surely this article should have a section on the safety of THC as it is a major point of disagreement among experts that directly affects the FDA's consideration of THC as a drug candidate. Other pharmaceutical articles clearly have sections on safety and side effects, but this article appears to limit discussion of safety to toxicity. We wouldn't want to appear biased on the matter, as though safety were something to be overlooked, would we?  — Preceding unsigned comment added by 50.54.219.172 (talk) 16:11, 29 April 2023 (UTC)
replies: text: There is a fair bit of information addressing the safety concerns throughout the article. It is not collected in one place. It is also stated that very little research has been done to study this issue, and that its legal status in many countries prevents it from being studied for safety (short- or long-term) or efficacy for medical or other use. For now it's still a schedule I controlled substance in the US (i.e., unsafe for any human use), and the NIH hasn't been terribly friendly to research grant proposals that might contradict their administration's political position. (I suspect that will be changing, if it hasn't begun already.) However, there are sections in this article addressing toxicity, overdose, the WHO's position concerning its potential for dependency, and interaction with other drugs to the extent that such things are known. Dcs002 (talk) 00:38, 20 October 2023 (UTC)
thread_title:  Safety Concerns 

message: Does anybody have any sources for absorption, bioavailability, peak levels, and/or half-life if consumed as an oral spray or sublingually? These forms are available OTC or by prescription in many locations. The info should be out there, right? Thanks! Dcs002 (talk) 00:19, 20 October 2023 (UTC)
thread_title:  Pharmacokinetics - absorption - sublingual or oral spray? 

message: Delta-9-THC and Delta-8-THC was described, synthesized and studied as early as 1942 by Roger Adams but this fact keeps getting repeatedly removed. Roger Adams synthesized and studied THC over 20 years prior to Raphael Mechoulams study on Cannabis and THC.https://patents.google.com/patent/US2419937A/enhttps://pubs.acs.org/doi/abs/10.1021/ja01255a061https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933888/  — Preceding unsigned comment added by Gettinglit (talk • contribs) 23:37, 16 January 2024 (UTC)
thread_title:  Synthesized and studied as early as 1942, fact keeps getting removed =