Talk:B cell

message: Let us be consistent with the rest of Wikipedia / most of the published literature and either consistently use a dash, or not use a dash.  Similarly for T-cell or T cell.  — Preceding unsigned comment added by Mmcdougall (talk • contribs) 14:17, 11 June 2020 (UTC)
thread_title:  B-cell vs B cell 

message: Quote: "abbreviated "B" for the bursa of Fabricius, an organ uniqe to birds where B cells mature; the "B" does not stand for bone marrow, where they are created in all other vertebrates"
This is true to the history, but isn't there a will to redefine this, so that they can say "B is for bbone marrow" out in the schools? That it wasn't named after the bone marrow, does that have any significance? If people today say "B is for bone marrow" then thats is, right? The Immune system article does this, which I approve. —Sverdrup(talk) 21:48, 14 Jan 2004 (UTC)
replies: text: B-cells are just B(ursa), and the "bone marrow" thing is just wrong. Your synopsis about covers it, but VDJ recombination, clonal selection and deletion do need to be covered. JFW | T@lk 16:01, 7 Feb 2005 (UTC)
thread_title: Quote

message: As an immunologist studying mammalian B cell development, I know that it is not common for us, or any immunologist that I have met, to mistake the B in B cell for meaning bone marrow.
:Thank you for your suggestion! When you feel an article needs improvement, please feel free to make whatever changes you feel are needed.  Wikipedia is a wiki, so anyone can edit almost any article by simply following the  link at the top. You don't even need to log in! (Although there are some reasons why you might like to…) The Wikipedia community encourages you to be bold. Don't worry too much about making honest mistakes—they're likely to be found and corrected quickly. If you're not sure how editing works, check out how to edit a page, or use the sandbox to try out your editing skills.  New contributors are always welcome. JFW | T@lk 21:56, 14 May 2005 (UTC)
thread_title:  Edit note 

message: The first section on B cell formation basically just talks about antibody structure which although related, doesn't seem the right way or place in the aticle to discuss this.  —Preceding unsigned comment added by 195.194.252.133 (talk) 10:05, 19 October 2007 (UTC)
thread_title: Section on structure

message: I was surprised to note that the very important concept of secondary response, wherein the encounters with a foreign antigen that follow the first exposure, are much more intense, does not find a mention almost in the whole of wikipedia. I'm sorry if I would have overlooked its presence, but I believe, I have searched quite well.
So, I am starting this section. Further supplementation with figures (graphs) will be greatly helpful.
Regards.
Ketan Panchal, MBBS (talk) 13:57, 4 May 2008 (UTC)
thread_title: Secondary immune response

message: instead of
"and it is this molecule that allows the distinction of B cells from other types of lymphocyte"
can I say 
"and it is this molecule that distinguishes B cells from other types of lymphocyte"
seems a little more direct
looking at phrase "The BCR is a membrane-bound immunoglobulin,"
*since "immunoglobulin" links (redirects) to "antibody" can we say
*"The BCR is a membrane-bound antibody," or "The BCR is a membrane-bound immunoglobulin (antibody),"
*why? I think most laypeople are more familar with antibody than immunoglobulin
looking at phrase "Each B cell has a unique receptor protein "
*do we need to introduce another idea/phrase "protein" instead of just saying its a iG or antibody?
"cognate antigen"
*it's set up as a link, but there is no linking article
*I suppose it is a "matching" antigen
*the diagram in the article uses "matching antigen"
*can I say "cognate (matching) antigen"?
*we later have the idea of "epitope" ~ I'm not sure how they relate
76.64.176.92 (talk) 16:21, 14 June 2009 (UTC)
replies: text: Thank you for your suggestion. When you believe an article needs improvement, please feel free to make those changes.  Wikipedia is a wiki, so anyone can edit almost any article by simply following the  link at the top. The Wikipedia community encourages you to be bold in updating pages. Don't worry too much about making honest mistakes—they're likely to be found and corrected quickly. If you're not sure how editing works, check out how to edit a page, or use the sandbox to try out your editing skills.  New contributors are always welcome. You don't even need to log in (although there are many reasons why you might want to).  WhatamIdoing (talk) 05:55, 15 June 2009 (UTC)
thread_title: phrasing

message: There is a picture here of a lymphocyte that seems to be circulating freely in the blood stream, wich is amrked as a plasma cell. I dont know if I missed something major in the literature, but arent plasma cells stationary in lymphnodes and diffuse lymphoid tissue (ie Malt, GALT, Tonsils, spleen). B-Cells mainly migrate from the lymph node in the form of plasmablasts aswell. I find it kind of misleading showing one in free circulation after this, and wonder if I misunderstood the literature or if the image should be replaced?
Gremmer (talk) 15:18, 3 November 2009 (UTC)
thread_title:  Confirmation needed 

message: "these immature B cells migrate to the spleen, where they are called transitional B cells, and some of these cells differentiate into mature B lymphocytes" This is true in murine models but in humansit is more likely that mature naive B-cells are produced in the bone marrow (Perez-Andres M, Clinical Cytometry 2010) :
1) Fully mature Naive B-cells are detected in human bone marrow (Van Lochem Clinical Cytometry 2004)
2) B-cells undego negative selection (deletion of autoreactive B-cells) between the immature and the naive compartments.
3) Aesplenic individuals have normal numbers of fully mature Naive B-cells (Wasserstrom H, JI 2008)
I would recommend to review this section  —Preceding unsigned comment added by 212.128.135.81 (talk) 15:49, 22 October 2010 (UTC)
thread_title:  Development of B-cells 

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thread_title: File:Phagocytic B-cell NI.gif Nominated for speedy Deletion

message: I have read from molecular biology text books that B-cell activation is Th2 mediated for neutralizing antibodies and Th1 mediated for complement fixing + opsonizing antibodies. If someone can provide reference to this, the paragraph "T-cell mediated activation" should be modified.
Molbil (talk) 16:40, 3 October 2011 (UTC)
thread_title: B-cell activation

message: Just read this NY times article and was wondering if the material would be relevant for this article. For example: what would be the side effects of someone never having B cells the rest of their life, and is this potentially as bad or worse than leukemia? Ranze (talk) 22:43, 10 December 2012 (UTC)
thread_title: B cell annihilation by HIV to destroy leukemia

message: I am trying to go from zero to understanding the B cell and the seemingly infinitely complex immune system. So try not to confuse me!
Where do B cells mature? I see in the Development section:
"...immature B cells migrate from the bone marrow into the spleen...Once differentiated, they are now considered mature B cells..."
Whereas, in the Activation section, I see:
"After B cells mature in the bone marrow..."
Please - either point out where I am misinterpreting your statements or make a decision and correct the incorrect statement. Believe me, I don't need any help being confused!
Thank you for your time, Wordreader (talk) 23:10, 10 February 2020 (UTC)
thread_title:  Info conflict?