Talk:Ehlers-Danlos syndrome

message: Hi, I noticed the "Prognosis" section appears to have been lifted wholesale from another site. Particularly bad as the tone of this text is at times not really encyclopaedic. Perhaps it could use a clean-up if anyone has good references for this info?  —Preceding unsigned comment added by 93.97.29.181 (talk) 14:46, 20 April 2009 (UTC)
thread_title: Plagiarism

message: ednf.org says there are six types, not ten
:Please correct it, with a good reference. JFW | T@lk 08:50, 12 Oct 2004 (UTC)
replies: text: OK, well done. JFW | T@lk 08:51, 12 Oct 2004 (UTC)
thread_title: ednt.org

message: Bone deformations such as pectus excavatum (sunken chest) from extra-rapid bone growth may present early.
That is accurate for Marfan Syndrome, another connective tissue disorder, but I question whether it it true of EDS. Source? Paleorthid 16:28, 2 Feb 2005 (UTC)
replies: text: I found this source  linking ED and PE, but it is kind of a "non-mainstream" nutrition-is-everything site. Gzuckier 16:00, 19 December 2005 (UTC)
replies: text:  I have a friend with ED, who would be expected to know of such things, and she said that she has never heard of pectus excavatum being a symptom herself, so if PE is a known symptom, it would be reasonable to assume it is rare.
It is not known whether some of the genetic variation represented by the various subdisorders of Ehlers-Danlos syndrome or other connective tissue disorders might not represent survivals of genes (rather than more recent harmful mutations of genes) which genetic variations were not problematic before humans began cooking meat a half-million years ago, or ceased using meat jerky and raw milk, thus eliminating sources of raw collagen from the human diet.
This appears to be highly speculative.  Wouldn't digestion destroy raw collagen regardles of cooking?  Source? Paleorthid 16:28, 2 Feb 2005 (UTC)

text: I can't imagine any circumstances where collagen from the diet could possibly be utilized without being broken down into amino acids. Plus, there isn't any collagen in milk. Gzuckier 05:38, 3 Feb 2005 (UTC)
thread_title: Accuracy questioned - Source requested

message: I restored a big hack-job from last october, but now the subsequent edits like the infobox have to be readded. I'll do some too if nobody does them first. Gzuckier 15:53, 19 December 2005 (UTC)
thread_title:  retro-edit 

message: a table form for symptoms would be easier to quickly read.  Can we add that somehow? Tkjazzer 23:42, 6 September 2007 (UTC)
thread_title:  convert / add a table form for symptoms for faster reading. 

message: Personally, I'd like to see the article expanded to reflect upon the fact that it's not very well known even among physicians (Despite being fairly "common"), has often been misdiagnosised as rheumatic or other diseases, and danger during urgent surgery. Would this be a good idea? Tubba Blubba (talk) 03:13, 6 May 2008 (UTC)
replies: text: Can you find a reliable source that makes this claim?  If so, then it would be fine to expand on that point.  WhatamIdoing (talk) 23:23, 6 May 2008 (UTC)
thread_title:  Misdiagnosis and general lack of knowledge among phyisicians? 

message: historical review oddly in a haematological journal. JFW | T@lk 23:58, 7 May 2008 (UTC)
thread_title: History

message: i think so. says so in medical text. please confirm before we change.  —Preceding unsigned comment added by 207.151.245.128 (talk) 23:46, 27 October 2008 (UTC)
replies: text: That's a matter of style, not accuracy.  Either approach is correct, and the simplicity of actual numbers is probably preferable.  Not every reader of the English Wikipedia will have learned Roman numerals.  WhatamIdoing (talk) 03:53, 28 October 2008 (UTC)
thread_title:  shouldn't the types be roman numerals? 

message: Revision as of 18:28, 20 March 2009: "It is a very serious, sad disease that can in some cases lead to death. Because of its rarity, not many doctors or specialists are even familiar with the disease, making a cure very difficult to conjure. Many with the disease suffer from a great deal of pain at all times. In some cases, a medication labelled Tremadol can be used to help minimize pain. However, not all types react favorably to it, and it should therefor be clarified with a specialist before taking the medication."
This does not seem objective nor does the tone seem appropriate. I also question the Tremadol accuracy. EDS patients use a variety of medications. Jdybka (talk) 02:37, 24 March 2009 (UTC)
replies: text: Hm, I missed that edit. Agreed, and so reverted. Thanks for pointing it out. Maralia (talk) 02:50, 24 March 2009 (UTC)
thread_title:  Tone, objectivity, accuracy questioned 

message: From NIH, claimed to be type IV:
 --CopperKettle 09:00, 4 May 2009 (UTC)
replies: text: I don't know why this pic is here.  This pic is supposed to be showing a patient with the BLUE SCLERA from EDS TYPE VI (not IV).  Case 464 at the same site does a much better job of demonstrating the blue sclera.Walking Softly (talk) 10:58, 11 May 2009 (UTC)
thread_title: Image

message: Removed the link to http://librarianinblack.typepad.com because links to blogs are to be avoided according to point 11. of Wikipedia:External_links_to_avoid#Links_normally_to_be_avoided.  Langhorner (talk) 14:37, 2 June 2009 (UTC)
replies: text: The specific link was Hello. My Name is Sarah, and I Have Ehlers-Danlos Syndrome. --LegitimateAndEvenCompelling (talk) 04:07, 3 June 2009 (UTC)
thread_title:  External links to avoid 

message: An anon has removed the detailed explanation of the various subtypes of this syndrome in this edit. They have also made what appear to be useful edits to this article, so I do not believe it is vandalism. The material removed had some inline references. Could someone with better knowledge of the syndrome please review their edits.-gadfium 19:38, 23 August 2009 (UTC)
replies: text: Removing the information was not, IMO, vandalism, but was probably unwarranted.  It could use a good copyedit and some effort to round up a few more sources, though.  WhatamIdoing (talk) 00:15, 19 October 2009 (UTC)
thread_title: Removal of types

message: in the intro section: "The collagen in connective tissue helps tissues to resist deformation (decreases its elasticity). In the skin, muscles, ligaments, blood vessels, and visceral organs collagen plays a very significant role and with increased elasticity, secondary to abnormal collagen, pathology results."  I found this confusing; is it just me?
in the Signs section: "In each case, however, the signs are ultimately due to faulty or reduced amounts of Type III collagen." However,the article further states that Ehlers-Danlos syndrome can be caused by faults in other types of collagen as well.
Jdybka (talk) 06:32, 16 March 2010 (UTC)
replies: text: When you think something needs clarity, feel free to look it up on a variety of sources before asking about whatever questions need to be answered. Wikipedia is a wiki, so anyone can edit almost any article by simply following the  link. You don't even need to log in. (Although there are some reasons why you might like to do so...)
The Wikipedia community encourages you to be bold. Don't worry too much about making honest mistakes—they're likely to be found and corrected quickly.  If you're not sure how editing works, check out how to edit a page, or try out the sandbox to try out your editing skills. New contributors are always welcome.
Places to start researching include (but are not limited to):
* Any search engine, such as Google or Yahoo
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*If you're just looking for answers to your questions, you can try the Wikipedia Reference Desk, although reliability is not guaranteed and answers given should not be used as resources for any academic paper or encyclopedia article.
WhatamIdoing (talk) 21:29, 16 March 2010 (UTC)
thread_title:  Accuracy questioned 

message: About this:
I'm not sure that your assertion is true.  Some sources say that BJHS is simply another name for EDS III.  
See , for example, which concludes that "There is no reliable method of differentiating between Joint Hypermobility Syndrome, familial articular hypermobility and Ehlers-Danlos syndrome (hypermobile type), suggesting these three disorders may be different manifestations of the same spectrum of disorders" -- in short, that they're probably the same actual disease, just under slightly different appearances.
 goes further, and says that there is "compelling evidence" that BJHS is a forme fruste of EDS III, and that the "widely held view" is that BJHS is "identical with" EDS type III. 
On the other hand... the labels seem to be used differently in practice, and I'm not sure that the specific definitions are really properly settled.  It would be nice to have a really stellar source, like a consensus statement from a large specialist organization, to give us some direction here. WhatamIdoing (talk) 00:04, 1 May 2010 (UTC)
thread_title:  Benign joint hypermobility syndrome