Talk:Thebaine

message: Thebaine isn't used to make codeine, hydrocodone or hydromorphone. All 3 are made from morphine. Thebaine is a much more expensive precursor than morphine and drug companies use the cheapest route.
:Wrong about one thing. Codeine is a natural opioid found in opium along with morphine and thebaine.--Metalhead94 T C  18:09, 30 November 2008 (UTC)
thread_title: Untitled

message: historically, thebaine was extracted from both indain and turkish opium.  in the laste 60s and early 70s,it was also extracted from seized opium from afghanistan.  The assay of thebaine was direcly affected by the timing of the harvest/lancing of the capsules.  In india, farmers were paid for morphine content, so thebaine assay could range from 2 to 5 per cent.
thebaine was used almost exclusively for the production of oxycodone until the early 1970s.  the amount of oxycodone required almost matched the thebaine extracted from indian opium for products such as percodan and percocet tm. In the early 70s ,thebeine was also used for developmental quantitiies of the new family of nal products.  However there was not enough thebaine to support the growth of the nal products, and new patented and unpatented routes to the nals were developedvia morphine.  however,as the demand for oxycodone continued to grow, work began to develop strains of poppies that would yield high levels of thebaine,as opposed to morphine.  initial plant selection work was done in france, with additional mutant strains  developed in tazmania and austrailia.  this was necessary to suppor t the introduction of purdue fredericks oxycodone product, oxycontin tm.  in addition, for a period of time, thebaine was synthesized from codeine until an adequate source could be harvested. today thebine is grown in large quantities in france,australia and tazmania, while some is still extracted from indian opium. ````  —Preceding unsigned comment added by Groodle (talk • contribs) 16:55, 15 December 2008 (UTC)
replies: text: Get some reliable references for that story and you could add some of it to the article. Otherwise, it would be treated as an anecdotal report and removed.--Metalhead94 T C  22:01, 20 December 2008 (UTC)
thread_title:  thebaine practical 

message: oripavine is very chemically close to thebaine.  currently, oripavine can be converted into thebaine, inceasing the overall supply, as oripavine is found in the same mutant strains of poppies from australia and tazmania.````  —Preceding unsigned comment added by Groodle (talk • contribs) 17:15, 15 December 2008 (UTC)
replies: text: Yes, that is true. Oripavine is a metabolite of thebaine. However, I don't see many indications that this is a common practice.--Metalhead94 T C  22:07, 20 December 2008 (UTC)
thread_title:  today... 

message: What is the mode of action of Thebaine as a stimulant? The areas of action in the CNS and the pharmacological functionality in technical terms to that effect? Nagelfar (talk) 07:20, 20 December 2010 (UTC)
replies: text:  I'd like to know too. --SlimNm (talk) 23:23, 25 December 2010 (UTC)
thread_title:  Stimulant 

message: Substituted at 08:31, 30 April 2016 (UTC)
thread_title: Assessment comment