Talk:Mastocytosis

message: c-kit mutations are common in SM] Imatinib, anyone? JFW | T@lk 06:58, 27 September 2006 (UTC)
thread_title:  c-kit 

message: THERES TREATMENTS FOR THE SYMPTOMS BUT IS THERE PREVENTIONS FOR THE PROBLEM? LIKE EATING CERTAIN FOODS AND THE REST?  —Preceding unsigned comment added by 24.188.17.249 (talk) 16:37, 16 May 2008 (UTC)
thread_title:  PREVENTION 

message: Doxepin is an tricyclic antidepressant at 150mg or greater however at lower doses doxepin acts more as an antihistamine. Doxepin is a strong H1, H2 and H4 antihistamine. H1, H2 and H4 receptors are dominant on the human mast cell making doxepin something of a mast cell stabilizer. The trouble with using doxepin to treat systemic mastocytosis is people with this disease may have abnormal serotonin levels so even at a very low dose there is a risk of serotonin toxicity. Usually the benefits here outweigh the risk of trying doxepin as its effective against bone pain, neuropathic pain, dementia and flushing. I'm speaking from experience here as a patient however I will try to get you some references. Buddha443556 (talk) 16:32, 29 November 2010 (UTC)
thread_title:  Doxepin 

message: Two symptom that are missing from the mastocytosis page is dementia and delirium. Mastocytosis patients refer to it as brain fog. Realize the is one of the most disabling symptom of systemic mastocytosis if your thinking is impaired there is not much in the way of work you can do and you will be lucky to be able to care for yourself. See http://www.psychosomaticmedicine.org/cgi/reprint/48/6/437.pdf Buddha443556 (talk) 16:46, 29 November 2010 (UTC)
thread_title:  Dementia 

message: Hello to all! I am proposing a merge from the following articles into this article:
* Diffuse cutaneous mastocytosis
* Erythrodermic mastocytosis
* Adult type of generalized eruption of cutaneous mastocytosis
* Xanthelasmoidal mastocytosis
This is for the following reasons:
* These articles are very short in length (1-2 sentences) and have not been edited significantly in 3-4 years.
* This knowledge shouldn't be obscured from readers of this article by virtue of being isolated in an obscure article of 1-2 lines.
* These topics may receive more attention by being mentioned in the main article.
* The articles, if needs be, could be re-expanded at a later date.
Kind Regards, LT90001 (talk) 13:21, 9 August 2013 (UTC)
thread_title:  Proposed merge 

message: doi:10.1186/s13054-015-0956-z JFW | T@lk 09:01, 12 June 2015 (UTC)
thread_title:  Critical care management 

message: doi:10.1056/NEJMra1409760 JFW | T@lk 22:44, 8 July 2015 (UTC)
thread_title:  NEJM 

message: Blood 2017 129:1420-1427; doi:10.1182/blood-2016-09-731893 JFW | T@lk 09:45, 17 March 2017 (UTC)
thread_title: WHO 2016

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thread_title:  External links modified 

message: I think there should be mention of Darier's sign, where when a lesion is scratched it creates a erythematous and pruritic response.  — Preceding unsigned comment added by 2607:FEA8:3C20:111A:6D9D:99F:470A:77CA (talk) 18:28, 20 August 2018 (UTC)
thread_title: darier's sign

message: Br J Haem doi:10.1111/bjh.16288 JFW | T@lk 13:47, 4 February 2020 (UTC)
thread_title:  Review 

message: Hmmmm. I came to this page because I have massive sun-exacerbated skin rash on my forearms, almost certainly caused as a side effect to my immunotherapy (Keytruder for metastatic ureterial cancer). My local doctor suspects possibly also mastocytosis, also from the immuno, and says that there is a specific blood test for it. THere is no mention of a blood test under Diagnosis that my non-knowledge of medicine can discern.  — Preceding unsigned comment added by 2001:8003:E422:3C01:1D88:2285:7779:B2F9 (talk) 02:01, 29 January 2021 (UTC)
thread_title:  Another diagnosis?