Talk:Dihydrotestosterone

message: Does green tea lower DHT? the paragraph on this seems conflicting
"DHT is thought to be approximately 30 times more potent than testosterone." For doing ... what? In all cases? Isidore 21:19, 8 Jun 2005 (UTC)
replies: text: Well, DHT has more affinity to the androgen receptor, and is therefore more potent in every aspect. JFW | T@lk 22:31, 8 Jun 2005 (UTC)
thread_title: Section

message: This page says DHT is about 30 times more potent than testosterone, but the article testosterone says DHT is 2.5 times more potent than testosterone. I suppose it is all apprioximations, but it looks confusing. / Habj 23:19, 7 November 2005 (UTC)
replies: text: Alzheimer's is not an immune disease. Nor is heart disease or cancer, at least not primarily. There is no evidence whatsoever that finasteride causes any clinical immune dysfunction. Th1/Th2 balance is a laboratory measure. Please do not insert original research on Wikipedia. JFW | T@lk 16:00, 7 June 2006 (UTC)

text: Causes PCOS? Or are elevated levels just associated with PCOS? --Ryan Wise 10:30, 1 August 2006 (UTC)
thread_title:  andrdogenic potential of DHT / testosterone 

message: Isn't the systematic name 5-alpha-androstan-3-one-17-beta-ol? Jack Daw 17:08, 26 August 2007 (UTC)
thread_title:  systematic name 

message: there's no normal ranges on here for dht, does anyone know what a normal dht range should be? Nemo.shark (talk) 03:43, 5 January 2008 (UTC)
thread_title:  normal range or estimates for dht? 

message: DHT and Testosterone are often referred to throughout scientific literature in the same breath.  They are both androgens, and likewise, tend to affect the same target tissues (though sometimes in very different ways).  I'm curious, though, about the hormone receptors on those target tissues.
I've read several articles which make mention of "androgen receptors" or "androgen sensitivity", but I've yet to find something which makes clear if DHT and Testosterone utilize the same receptors on target tissues, or different ones.  Does DHT bind to the exact same type of receptor as testosterone?  And if so, how do drugs like finasteride regulate one, without impacting the other?
Pine (talk) 23:20, 9 January 2008 (UTC)
replies: text: finasteride inhibits conversion of testo to the more active form, DHT. The target receptors are the same.195.5.116.150 (talk) 16:39, 12 November 2008 (UTC)
thread_title:  DHT receptor question 

message: This is a rather strange topic that came up today while I was having a discussion with co-workers during our lunch break: According to the article, DHT is present in the testes, thus assumed to be a byproduct or semen (or semen is a byproduct of DHT). Does that mean (is there any scientific or at least some sort of experiment proving) that if a male individual ingests semen over a period of time that androgenic alopecia, or male pattern baldness, is more prone to occur? In other words, if a male ingests his semen on a regular basis, would he begin to show signs of male-pattern baldness over time? --SetandSpike (talk) 05:26, 15 January 2008 (UTC)
replies: text: eew.  —Preceding unsigned comment added by 133.62.200.220 (talk) 05:13, 2 April 2008 (UTC)
replies: text: I think the point you're missing is that too much masturbation over the course of a single day causes balding.  Not semen ingestion.  I'll go further and say it has to due with digestion, the fact that male masturbation causes a loss in zinc or other vitamins.  These vitamins are required in new hail growth.  Men tend to have a low intake of these particular foods.  On top of that as they age, their intestines have poor absorption rates of these foods/vitamins. --172.251.204.186 (talk) 00:48, 23 October 2015 (UTC)
thread_title:  DHT and Semen 

message: Most / many of the :Category:Sex_steroids articles lack citations for the "IUPAC" names... is IUPAC really the same as a "systemic name" from List_of_steroid_abbreviations if so, why are there so many "red links" on that list?... neither the steroid list page, nor the pages in the sex steroid category are citing sources for the "systemic" or IUPAC names. --Kuzetsa (talk) 17:46, 12 October 2008 (UTC)
thread_title:  citations / sources for IUPAC names on this and many "sex steroid" articles 

message: I was wondering what did the person who added this section thought; DHT isn't an illness or disorder, so there couldn't be (obviously) a treatment.  —Preceding unsigned comment added by 82.131.222.224 (talk) 23:15, 6 April 2010 (UTC)
thread_title:  Could someone explain why is a "Treatment" section there? 

message: I want to include some info about DHT metabolism and the effects of its metoblites on prostate cancer. Seems important since the NEJM Porstate Cancer Precention Trial is very related. Drbarrywheeler (talk) 17:17, 3 August 2010 (UTC)
thread_title:  DHT Metabolism 

message: This article currently states:
:"DHT has 3 times greater affinity for androgen receptors than testosterone and has 15-30 times greater affifinty than adrenal androgens."
There should be a definition of adrenal androgens. The article androgen defines adrenal androgens as "[a] subset of androgens [which] includes any of the 19-carbon steroids synthesized by the adrenal cortex [...]". 
Yet the article adrenal cortex mentions DHT itself as an adrenal androgen, giving DHT 15-30 times more affifinty [sic] than DHT [sic]. --Abdull (talk) 11:12, 21 August 2010 (UTC)
thread_title:  Clarification needed - adrenal androgens 

message: Should not the two isomers not be discussed? Produced by the action of two isomers of 5α-reductase from different genes. One has most potency as a sex steroid and the other with male pattern baldness. The topic only gets mentioned in the last paragraph and type I and type II is not explained 2.31.6.253 (talk) 12:08, 2 January 2015 (UTC)
thread_title: Isomers

message: doi:10.1210/er.2016-1067 JFW | T@lk 18:52, 12 June 2017 (UTC)
thread_title:  Physiological role in doubt 

message: This is a condition that has a complex description, there are a number of misconceptions and errors in this section (many poor quality references). This article shouldn't describe much past the important role the condition has played in discovering the biological role of DHT.  This section should be shrunk down to no more than a para, focusing on DHT and should link to 5α-Reductase 2 deficiency Maneesh (talk) 06:15, 10 September 2021 (UTC)
thread_title:  Numerous problems with "5α-Reductase deficiency" 

message: I check pages listed in :Category:Pages with incorrect ref formatting to try to fix reference errors. One of the things I do is look for content for orphaned references in wikilinked articles. I have found content for some of :Dihydrotestosterone's orphans, the problem is that I found more than one version. I can't determine which (if any) is correct for this article, so I am asking for a sentient editor to look it over and copy the correct ref content into this article.
Reference named "pmid30763313":
From Progesterone: 
From Androgen backdoor pathway: 
I apologize if any of the above are effectively identical; I am just a simple computer program, so I can't determine whether minor differences are significant or not. Feel free to remove this comment after fixing the refs. AnomieBOT⚡ 20:04, 23 May 2023 (UTC)
thread_title:  Orphaned references in [[:Dihydrotestosterone]]