Talk:Benzonatate

message: The following sentence in Society and culture needs edited, as dextromethorphan is opiod-based not opiate based also it isn't sold by prescription.  You can buy dextromethorphan over the counter at virtually any drug store.
"There are a variety of prescription opiate-based cough relievers, such as dextromethorphan and codeine, but have unwanted side effects and potential of abuse and diversion."  — Preceding unsigned comment added by 156.146.51.11 (talk) 02:05, 13 September 2020 (UTC)
replies: text: I don't believe the article mentions codeine anymore but just to address this issue, I agree that the article you cited states that benzonatate has serious adverse effects. It does not explicitly compare benzonatate to codeine in any way, shape, or form and it would be presumptive to compare their efficacies or safety profiles without the proper systematic review of head to head trials. Thank you. DocWock (talk) 02:33, 21 April 2020 (UTC)
thread_title: "Society and culture"

message: Hello, I am DocWalk, a rising PGY1 in a US residency, and I would like to work on this page for Wikiproject medicine. I believe that the core content of the page is structurally sound but there are areas that need expansion, clarification, and citations. I will be using secondary and tertiary sources as well as the FDA information within package insert and drugs.com (which references the FDA label). I will be working on the following sections:
Lead
* The section uses references and statements that are not supported elsewhere in the article e.g. hiccups, pediatric contraindication, and marketing
* I believe the brand name is "tessalon perles" and not simply "tessalon",minor issue so will leave and discuss further
Medical uses
* update medical uses based on FDA label and secondary/tertiary sources, attempt to differentiate its use in chronic vs acute cough if possible
Contraindications
* create section, use FDA label, although its only contraindication is a previous hypersensitivity reaction to the medication
Adverse Effects
* expand section as needed with new developments e.g. mood changes
* create special population section for pediatric, pregnancy, and breastfeeding
Pharmacology
* create section, move mechanism of action into this
* move chemical structure into this
* current research does not define pharmacokinetics and metabolism it seems
Dosage and administration
* WikiPharmacy manual of style explicitly states "Detailed dosage information is not recommended as it may be construed as medical advice and be easily subject to vandalism or uninformed good-faith edits"
* clarify routes of administration in infobox that the medication is a softgel capsule
* section should be removed from article
Society and culture
* create section based on marketing and popularity of use, cited within secondary and tertiary sources
Research
* create section
* FDA label about carcinogenic/mutagenesis/inferility
I am open to comments and suggestions on this talk page or my user talk page. Please feel free to make changes to my edits. Thank you. DocWock (talk) 02:21, 21 April 2020 (UTC)
thread_title:  WikiProject Medicine April 2020 

message: The author states that benzonatate “is not available in many countries.” (Citing footnote [6], Walsh, T. Declan; Caraceni, Augusto T.; Fainsinger, Robin; Foley, Kathleen M.; Glare, Paul; Goh, Cynthia; Lloyd-Williams, Mari; Olarte, Juan Nunez; Radbruch, Lukas (2008). Palliative Medicine E-Book). 
That source, however merely states that “[a]vailability worldwide is limited.”  It does not follow that because worldwide availability is limited, benzonatate, therefore, is “not available in many countries.”  Further, it is notable that the cited source fails to cite supporting authority for its proposition regarding limited “worldwide” availability. Therefore, this extrapolation is unsupported by authority Hendricks91022 (talk) 05:20, 10 December 2022 (UTC)
replies: text: This appears to be fixed in the current page with the correct quotation. Paulehoffman (talk) 03:07, 10 February 2023 (UTC)
thread_title:  Proposition needs support