Talk:Trimethoprim/sulfamethoxazole

message: I have had this medication prescribed for a parasitic infection (Cyclospora).  I've also found it indicated for this purpose in a physician's handbook.  Can anyone confirm this? --StarKruzr 17:44, 11 August 2006 (UTC)
thread_title: Other uses

message: This is a very British-centric article. In the US, IDSA recommends TMP/SMX as the first-line agent in uncomplicated UTI. - Emt147 Burninate! 07:01, 11 October 2006 (UTC)
replies: text: By all means edit the article to reflect that? --Gak 10:50, 21 May 2007 (UTC)
thread_title:  Uses 

message: Me too! I've taken it twice a day for 5+ yrs now. I came here because I'm wondering if it's a bad thing for me to do, especially with Gilbert's Disease. If anyone wants to save my life, feel free to message me ;) ClintJCL (talk) 23:47, 28 October 2008 (UTC)
thread_title:  i used to use it for acne 

message: How much is a safe dose? What constitutes an overdose? Is it taken once or twice daily?—Preceding unsigned comment added by 65.43.224.247 (talk • contribs) 00:17, 14 May 2007
:Wikipedia dose not state dosages (see WP:MEDMOS) this being a matter to discuss with ones own physician. Like all drugs, it depends on the condition to be treated, body size, age and often if known liver or kidney disorders. David Ruben  Talk  00:23, 14 May 2007 (UTC)
thread_title: Dosage

message: I'd like to add in the fact that in Canada co-trimoxazole is considered a first-line agent for skin and wound infections in patients who have a demonstrated true allergy to penicillin, but I can't find an online reference that isn't behind a paywall. Does anyone have one? --Charlene 14:31, 17 July 2007 (UTC)
thread_title: Better source for information?

message: When I was a child, my doctor had given me type of this medication, septra, for an ear infection. It resulted in an allergic reaction. Does this mean I have a type of SJS, Steven Johnson Syndrom?  —Preceding unsigned comment added by 69.227.69.194 (talk) 06:21, 24 June 2008 (UTC)
thread_title: Question

message: This is the term my pharmacopoeia uses and thus move here. Doc James (talk · contribs · email) 10:12, 8 November 2010 (UTC)
thread_title: Why is this page not called Trimethoprim-sulfa?

message: I notice that erythromycin and teracycline are safe for long-term use in patents not allergic to them, but cephalexin is considered only for short term use.  What about TPM-SMZ? -Reticuli 66.178.144.102 (talk) 21:20, 23 April 2011 (UTC)
thread_title: Safe for long-term use?

message: Anyone aware of any research indicated it's ototoxic, like some other antibiotics? -Reticuli 66.178.144.102 (talk) 21:33, 23 April 2011 (UTC)
replies: text: No. Antibiotic-related ototoxicity is mostly restricted to the aminoglycosides and, to a far lesser extent and for different reasons, the macrolides. The diuretic furosemide (a sulfonamide, as is sulfamethoxazole) can be ototoxic, but the effect has nothing to do with the sulfa structure. Fvasconcellos (t·c) 21:58, 23 April 2011 (UTC)
thread_title: Ototoxicity

message: The Committee on Safety of Medicines ceased to exist in 2005, so it can't have current guidelines.  The Commission on Human Medicines may have the same current guidelines, but I don't know.  I hope someone can dig out a relevant citation PRB (talk) 13:06, 17 July 2012 (UTC)
thread_title:  CSM Current Guidelines 

message: Co-trimoxazole is recommended for what used to be called Wegener granulomatosis limited to the upper respiratory tract, because of its favorable adverse effect profile compared to the other treatments. 
http://jama.jamanetwork.com/article.aspx?articleid=208292
JAMA. 2007;298(6):655-669. doi:10.1001/jama.298.6.655
--Nbauman (talk) 04:49, 14 February 2013 (UTC)
thread_title:  ANCA vasculitis 

message: Hi, people, I'm sorry if me changing the lead pic to two structural images causes any upset but I feel something more informative about the properties of the drug would be more helpful as a lead pic in the drugbox. Fuse809 (talk) 09:11, 7 January 2014 (UTC)
thread_title: Front pic

message: This source gives a better overview https://www.drugs.com/pregnancy/sulfamethoxazole-trimethoprim.html
Specifically "LactMed: Use is considered acceptable when breastfeeding healthy, full-term infants after the newborn period; alternate agents are recommended in jaundiced, ill, stressed, or premature infants. Use should be avoided while breastfeeding glucose-6-phosphate dehydrogenase (G6PD)-deficient infants." Doc James (talk · contribs · email) 21:15, 21 November 2019 (UTC)
replies: text: So how do you propose summarizing it? Doc James (talk · contribs · email) 01:07, 22 November 2019 (UTC)
thread_title: Breastfeeding

message: This article should be named Sulfamethoxazole/trimethoprim to match the order in the drugs.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f59d0c04-9c66-4d53-a0e1-cb55570deb62
https://www.ema.europa.eu/documents/psusa/sulfametrole/trimethoprim-sulfadiazine/trimethoprim-sulfamethoxazole/trimethoprim-co-trimoxazole-list-nationally-authorised-medicinal-products-psusa/00010593/201903_en.pdf
The WHO EML uses sulfamethoxazole + trimethoprim
Whywhenwhohow (talk) 03:36, 15 April 2020 (UTC)
thread_title:  Article title