Talk:Nucleic acid

message: Hi guys. Want to talk about it? Preemptively, I will ask you to restrict your comments to the text of this article. -- Cyan 18:56, 17 Jan 2004 (UTC)
thread_title: Protected

message: Unfortunately, this article has become a gated community. Any edits a general contributor would like to make can be written here, and I will implement them. Lir, 168, continued reversion of this page will accomplish nothing. 
As a point of logic, I will note, Lir, that your justification (nucleic acids are not studied in just biochemistry) is flawed, because, as 168 has pointed out, his preferred version does not state that nucleic acids are only studied in biochemistry. -- Cyan 05:41, 30 Jan 2004 (UTC)
thread_title: Protected

message: The very first sentence of the article, currently protected, is confusingly punctuated: "The nucleic acids, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are..." should be: "The nucleic acids -- deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) -- are..."
Who knows how long this senseless dispute will drag on (C'mon, this article has only three puny paragraphs! Spend time enrich it instead...), so I'll leave a note here now, in case I shall never come upon this article again. --Menchi 05:41, 12 Feb 2004 (UTC)
thread_title:  Punctuation 

message: Hydrophobic interaction of nucleic acids is poorly understood.
What is the basis for this claim?  I have never heard that there is any particular mystery about nucleic acids and the hydrophobic effect. Josh Cherry 01:10, 21 Oct 2004 (UTC)
thread_title: Hydrophobic Interactions

message: Is ATP a nucleic acid? --Enigma 20:13, 21 January 2006 (UTC)
thread_title: ATP a nucleic acid?

message: :Hydrophobic interaction of nucleic acids is poorly understood. For example, nucleic acids are insoluble in ethanol, TCA, cold and hot water, and diluted hydrochloric acid; but they are soluble in diluted NaOH, alcohol and HCl.
* Is this sentence really correct? Assuming that HCl is standing for the gas substance here, is DNA really soluble in a gaseous phase?
* And does the Hydrophobic interaction... introduction make sense here? I was under the impression that there is more to solubility than hydrophobic and -philic interactions.
--jοτομικρόν | talk 19:00, 15 March 2006 (UTC)
thread_title:  Ambiguous sentence 

message: I started a revision of the structure section when I spotted some spelling arrors, and then continued on to fix a few errors of fact (for example, the nucleoside sugars were referred to as hexoses; I chenged this to pentoses).  After the revisions, I checked this page and learned that this page has been locked to prevent revision wars.  I hope I did not offend anyone, but I am confident that the revisions I made improved the accuracy of the section.  I would be happy to discuss revisions.
JonMoulton 15:58, 26 January 2007 (UTC)
thread_title:  Hopefully not fanning the flames 

message: I think this article definately needs a clearer picture of the structure of a nucleic acid, I'm more than willing to do one myself but I'm wondering if anybody has any ideas on what level of detail I should include: stick to symbols for the phosphate, pentose and base groups or the molecular structure of those groups? Joey Roe 20:41, 7 February 2007 (UTC)
thread_title:  Illustration 

message: but it is an acid? 131.111.8.102 23:22, 13 February 2007 (UTC)
thread_title:  Acid? 

message: Hi, I believe you will find that the structure for your dCTP at your link below is in error. The double (imine) bond should be from N3 to C4, not C4 to the primary amino nitrogen. Best regards, Tim
 
http://www.swbic.org/products/clipart/images/nacollage.jpg
 Nucleic Acid Structures
--Tlavelle 21:36, 18 April 2007 (UTC)
thread_title:  structure error 

message: For example, nucleic acids are insoluble in ethanol, TCA, and diluted hydrochloric acid; but they are soluble in diluted NaOH and HCl.
this is self contradictory insoluble in diluted hydrochloric yet soluble in diluted HCl?! 152.91.9.170 04:54, 12 June 2007 (UTC)
thread_title:  Re acid 

message: In an effort to push this at least to B class on the project scale, I've started pulling in text from other articles. Note: if there are arguments as to whether or not nucleobases, nucleosides and nucleotides are nucleic acids, please rename the section headings, but don't delete the text. I really think it belongs in this article. Anyway, I'll be back to include some text from the other articles, as there's a wealth of material that can be summarised into this article to improve it. -Kieran 15:26, 8 July 2007 (UTC)
thread_title: Types of nucleic acids

message: I know this sounds a bit of a silly question but I have come here from the nucleotides page which is in need of a clean-up and find many redundancies in the nucleic acids page.  Nucleobases and nucleosides are not monomers of nucleic acids and should probably not be dealt with in detail on this page.  Nor probably should nucleotides except in brief with reference to the relevant page.  Surely this page should concentrate on nucleic acids their struture and biochemistry as an entity.  Rehashing nucleotide (monomer) structure along with nucleobases, nucleosides adds nothing to my understanding of nucleic acid biochemistry.  How do nucleic acids behave as polymer?  Role in gentcis expanded! Who elucidated their struture?  Double-stranded vs single stranded?  These are a few things I would like to see discussed, but do not have expertise as I am an analytical chemist.  
Suggestion: remove nucleobase and nucleosides from page and simply text in reference to nucleotide monomers.  I am right or way off base?--Strathallen (talk) 07:31, 22 December 2008 (UTC)
thread_title: What is a nucleic acid? And what constitues a nucleic acid?

message: Re editing copy: the repetitious copy is (again) deleted; pls note emphases of excess (bolded or underscored) at {A} vs {B} paras below. Jumbled information-flows are logically straightened. Now it reads—> definition::basic info::resultant key info; that is: nucleic acids ——>are monomers /nucleotides, ——>sugars, of which ——>result in RNA or DNA; ——>and relates info re chemical naming of sugars, RNA, and DNA; Good stuff for the lay reader!
This article is about 'nucleic acid', not 'nucleotides': the five mentions of nucleotides—here in the lede paragraph for nucleic acid—is excessive, and confusing to the lay reader. Explication of 'nucleotides' is easy to find at it's link-article.
{A:previous} Nucleic acids are biopolymers, or large biomolecules, essential for all known forms of life. Nucleic acids, which include DNA (deoxyribonucleic acid) and RNA (ribonucleic acid), are made from monomers known as nucleotides. Each nucleotide has three components: a 5-carbon sugar, a phosphate group, and a nitrogenous base. If the sugar is deoxyribose, the polymer is DNA. If the sugar is ribose, the polymer is RNA. When all three components are combined, they form a nucleotide. Nucleotides are also known as phosphate nucleotides.
{B:new} Nucleic acids are biopolymers, or large biomolecules, essential to all known forms of life. They are composed of monomers, which are nucleotides made of three components: a 5-carbon sugar, a phosphate group, and a nitrogenous base. If the sugar is a simple ribose, the polymer is RNA (ribonucleic acid); if the sugar is derived from ribose as deoxyribose, the polymer is DNA (deoxyribonucleic acid).
So ..,  definition, plus main arguments —simpler, logically-sequenced info, with more information and less verbiage. {Better stuff—and I charge less since I retired; regards, Charlie Clearwater}  — Preceding unsigned comment added by 67.79.157.50 (talk) 18:51, 26 January 2017 (UTC)
thread_title: I try again

message: Is there a good reason several of the headings have references in them? This is not typical of MOS. Andrew Z. Colvin • Talk 12:46, 27 November 2017 (UTC)
thread_title:  Reference  

message: Article states, " then store information in the nucleus of every living cell of every life-form organism on Earth", but prokaryotes (bacteria, archaea) don't have a nucleus, their DNA is "free-floating" in the cell. Might also be a good spot to mention mitochondria and choloroplasts have their own DNA, independent of the organism, and it is inherited matrilineally.  — Preceding unsigned comment added by 98.156.89.85 (talk) 13:59, 15 September 2019 (UTC)
thread_title:  Error 

message: Nucleic acid 192.145.174.244 (talk) 16:47, 25 October 2022 (UTC)
thread_title:  Human biology 

message: °The double helix DNA unwinds, 
Weak hydrogen bonds break, 
To form two separate strands, 
One strand is used as a template, 
to form mRNA, 
using free RNA nucleotides from the nucleoplasm, 
The mRNA is complementary to the DNA, 
mRNA now has the coded message for protein synthesis. Beyonce president daughter (talk) 15:21, 30 May 2024 (UTC)
thread_title:  transcription 

message: °Each tRNA carries a specific amino acid, 
when the anticodon on the tRNA, 
matches the codon on the mRNA, 
then tRNA brings the required amino acid to the ribosome, 
amino acids become attached by peptide bonds, 
to form the required protein. Beyonce president daughter (talk) 15:25, 30 May 2024 (UTC)
thread_title:  translation