Talk:T cell

message: The T cell receptor signalling pathway is described in much more detail here than it is in the T cell receptor article. I would like to add some more information about T cell receptor signalling and antigen discrimination models. Is it better to do this in this article or in the T cell receptor article? Huhny (talk) 12:53, 20 November 2019 (UTC)
thread_title:  T cell signalling 

message: The article has great depth on types of different T-cells, their development, etc, but a little more "why" rather than "how" and "what" would be great.  Even one sentence in the summary would go a long way, distinguishing their role from that of B-cells, for instance.   I'd be happy to take a crack at it, but it's probably better done by a true subject matter expert  — Preceding unsigned comment added by Rockfox212 (talk • contribs) 13:00, 2 August 2016 (UTC)
thread_title:  Purpose of T-cells 

message: Throughout the article the term is spelled without a hyphen (T cell), except in the accompanying image for T cell activation, where it's inconsistently spelled "T-cell"  and "T cell" - Can someone clarify the usage here? Is with or without hyphen preferred? Should there be a difference for hyphenated adejctives, as in "T-cell activation"?
Thanks, 216.165.126.18 14:30, 10 September 2007 (UTC)
replies: text: Thanks for clarifying! 216.165.126.18 16:17, 21 September 2007 (UTC)

text: That is the normal hyphenation rule in English. If "T cell" stands on its own as a noun phrase, then no hyphen is required. If "T cell" together modifies another noun (phrase), then a hyphen should be used, such as in "T-cell activation" or "T-cell lymphoma". --JorisvS (talk) 10:54, 22 October 2014 (UTC)
thread_title:  Hyphen or not? 

message: Since 2009 there has been discussion of mucosal-associated invariant T cells which seem to be activated by molecules presented by MR1 on antigen presenting cells. Should at least mention them here, then give them their own article. eg MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution. 2009, [http://www.nature.com/icb/journal/v88/n8/full/icb2010104a.html Innate T cells detect bacteria.
Bacteria, mucosal-associated invariant T cells and MR1. 2010], MR1 presents microbial vitamin B metabolites to MAIT cells. 2012 - Rod57 (talk) 03:12, 1 December 2012 (UTC)
replies: text: The problem is the balance between making a truly comprehensive article and a readable one - I've been trying for a while to stop this article drifting off into the latest and strangest subset and to keep it general and not involve every paper someone has read and decided is important. It's probably worth waiting until these cells have been better outlined before adding them. --Kantokano (talk) 06:06, 3 January 2013 (UTC)
thread_title:  Should mention MAIT cells 

message: Could it be explained or linked to somehow ? - Rod57 (talk) 13:03, 20 April 2015 (UTC)
replies: text:  Perhaps we could say : T-cell immunity is a type of Cell-mediated immunity involving Cytotoxic T cells ? - Rod57 (talk) 22:37, 10 February 2016 (UTC)
thread_title:  No mention of T-cell immunity 

message: Hello everyone, I added a genetic engineering section as human T cell genome engineering is starting to take off in 2015.  — Preceding unsigned comment added by Westernmgene (talk • contribs) 03:11, 28 September 2015 (UTC)
replies: text: Not helpful yet. Does not say what type of T cell, what the changes were, or if/how it relates to Chimeric antigen receptor. - Rod57 (talk) 22:51, 10 February 2016 (UTC)
thread_title:  Genetic Engineering 

message: The large Signalling/activation section only seems to mention CD4+ cells (~=T helper cells). Could move this section to T helper cell ?  Article only briefly mentions activation of other T cell types. - Rod57 (talk) 21:52, 10 February 2016 (UTC)
thread_title:  Why only CD4+ T cell activation described  

message: Naive T cell#Activation - Rod57 (talk) 23:01, 23 February 2016 (UTC)
thread_title:  Other summaries of T cell activation 

message: Doorland Medical Dictionary hyphenates this term
Source: https://www.dorlandsonline.com/dorland/iniSearch?searchterm=t-cell&searchtype=Within+Terms+and+in+Definitions
But a look at recently published medical journal articles shows that both "T-cell" and "T cell" are used.
My feeling is that, whichever is preferred, the article should pick one of these conventions and use it consistently throughout.
It may be that the hyphenated term is appearing in the links, which may need to be reviewed and revised.
PeacefulPlanet3 (talk) 00:51, 6 June 2019 (UTC)
thread_title:  "T cell" or "T-cell"? We should pick one and stick with it …. 

message: This article is missing a section on the History of the T-cell. Who discovered it? When? What are major milestones in research regarding it? Omegastar (talk) 16:37, 16 April 2020 (UTC)
replies: text: Very true. There are some references in the History section for Thymus, mentioning Jacques Miller's work. Perhaps a good place to start? IvanStepaniuk (talk) 13:17, 19 December 2022 (UTC)
thread_title:  History