Talk:Dextromethorphan/Archive 1

message: What is this sentence supposed to mean? -> "In addition to having a methoxy group that water (at 20 degrees Celsius, Sodium D-line) with a specific rotation of +27.6 degrees."
-anonymous 2
:It seems a big chunk of that paragraph was accidentally deleted at some point. I just fixed it. Thanks for pointing that out. Equazcion 10:09, 8 June 2007 (UTC)
thread_title:  Grammatical error? 

message: "Deaths and hospitalizations have been reported in recreational use by poor CYP2D6 metabolizers."
Considering there are very few DXM deaths at all.  I doubt that the few that have happened were caused by poor CYP2D6 metabolizers.
But I am willing to believe it if I see a some report even one of this being true.  So please, if we are going to make a claim like that lets provide a source.
Foolishben 20:50, 24 August 2006 (UTC)
replies: text: You're right, and the statement was removed. Equazcion 06:34, 21 February 2007 (UTC)
thread_title:  Dextromethorphan Deaths 

message: Sorry if I'm missing something obvious, but where did all the non-medical info mentioned above and still visible in eg. this edit just go?  I'm fine with putting it somewhere else, but we should at least mention that DXM has potential for more than just stopping coughs, and provide some sort of clear link to the new location! Jpatokal 07:53, 28 November 2005 (UTC)
replies: text: See: non-medical use of dextromethorphan. --Arm 09:44, 28 November 2005 (UTC)
thread_title:  Where did the non-medical info go? 

message: I think we should decide whether to merge the two articles. I'd be willing to do the work if the consensus is that the articles belong together. What do you think? Peoplesyak 23:02, 12 January 2006 (UTC)
replies: text: I've weighed in on this before... I believe that we should not merge the articles.  This is a unique situation in which the information on its non-medical use is often highly subjective and the length of it is too overwhelming to merge with the main article.  I feel that this fact becomes extremely important when looking at the primary use of Dextromethorphan.  The vast, vast majority of people use DXM when they're sick, and not to get high.  When merged, the overwhelming majority of the article will focus on getting high off of it, and this is very inappropriate.  This has been discussed to death and I really think it should remain as is.  RJSampson 20:14, 13 January 2006 (UTC)

text: I've taken the liberty of making the link a little more visible in the main article; I think this helps a lot without merging. Mgcsinc 15:42, 14 January 2006 (UTC)
replies: text: That helps, Mgcsinc; just not a good idea to merge RJSampson 06:32, 17 January 2006 (UTC)
thread_title: Merging non-medical use of dextromethorphan with main article

message: In undocumented events, Dextromethorphan has been known to cause intense hallucinations in the sense of seeing things or people who arn't there, such as seeing a fairy dancing ontop of a television and disapearing after a few seconds. These kind of hallucinations more commonly happen right when the user wakes up after a short amount of sleep.
:I think this post would be more appropriate in the non-medical use of dextromethorphan talk page. Why? Because if your getting such realistic and fully formed hallucinations, then you are probably taking alot more then the recommended dose. --Arm 05:09, 22 February 2006 (UTC)
replies: text: Unless one has an allergy to the substance. I'm allergic to Tylenol of all things and have hallucinated from child's doses. DEL 66.57.225.195 21:53, 19 July 2006 (UTC)
replies: text: What's the point of the post anyway? --Muugokszhiion 06:25, 23 February 2006 (UTC)
thread_title:  Dextromethorphan Hallucinations 

message: Read the "DXM for Chronic Pain" and "DXM for Drug Addiction" sections this erowid page.  They provide references you can use to verify rather than relying on Erowid itself.  I was informed by an expert that DXM and all other drugs which mitigate opiate tolerance are mediocre, at best.  Nathan J. Yoder 08:19, 20 April 2006 (UTC)
thread_title:  Reduces opiate tolerance 

message: Please cite a source for the information that says DXM is a dopamine reuptake inhibitor.
: Done. Link: http://www.nhtsa.dot.gov/people/injury/research/job185drugs/dextromethorphan.htm -- ×××jijin+machina | Chat Me!××× -- 20:43, 2 September 2006 (UTC)
thread_title:  Cite Source In Pharmacology 

message: Can anyone speak to the way this drug reacts along with SSRI's
Fluoxetine and other SSRI antidepressants, as well as tricyclics and lithium (and of course MAOIs) may interact with DXM to cause serotonin syndrome (see Section 6.2.9). This condition, although rarely fatal, is not terribly pleasant. Vascular disease may increase the chance for serotonin syndrome with DXM + antidepressants (364), and other disease conditions may do so as well. Some DXM users who have taken DXM while on antidepressants have reported unpleasant reactions that sound a lot like serotonin syndrome, so you might want to watch out. Some of the symptoms of serotonin syndrome include muscle rigidity, confusion, diarrhea, incoordination, low-grade fever, sweating, muscle tremor, mania, agitation, exaggerated reflexes, and nausea.
http://www.erowid.org/chemicals/dxm/faq/dxm_general_info.shtml#toc.4.16
The entire recreational section can be cited using Erowid, however I'm guessing that isn't considered a valid source. User experiences simply haven't been documented in any credible source. The US military hasn't experimented with it like they have with other hallucinogens :) But as for SSRI's, we can accurately assume the interactive effects with DXM because it is a matter of fact that all drugs that metabolize via the CYP2D6 pathway will interact with each other, at least decreasing each-others' effectiveness. Therefore most drugs that compete for CYP2D6 will carry an interactivity warning against use with other such drugs that metabolize the same way, and the effects of such an interaction are public knowledge.
Equazcion 13:41, 5 February 2007 (UTC)
thread_title:  Effect with SSRI's 

message: AfD Proposed Deletion Discussion Equazcion 16:50, 6 February 2007 (UTC)
thread_title:  Proposed deletion of [[Non-medical use of dextromethorphan]] 

message: Please merge any relevant content from [ Non-medical use of dextromethorphan] per Wikipedia:Articles for deletion/Non-medical use of dextromethorphan.  Thanks. —Quarl (talk) 2007-02-10 23:47Z
:*For those who were proponents of keeping the old non-medical use article, I would suggest collecting the data there that doesn't already exist in this article and inserting it (use the link above to see the deleted non-medical use article). Use your judgment as to what really deserves to be merged in; the recreational section of this article is already pretty long. As far as the History section, it's too long to merge in its current state, but perhaps condensing it into one or two paragraphs of "historical milestones" would make it an adequate sub-section of "recreational use" in this article. Equazcion 08:49, 13 February 2007 (UTC)
thread_title:  Merge from [[Non-medical use of dextromethorphan]] 

message: I don't know if its law or something else but Safeway and everyone else around me required you to be 18+ to buy it now i do not know if its state or federal laws or just a common business practice but in any case i feel it should be mentioned somewhereUser:Shimonnyman 08:35, 16 April 2007 (UTC)
thread_title: controlled

message: Most people say its more like pcp than anything else. I haven't tried either so I wouldn't know —The preceding unsigned comment was added by 141.155.144.199 (talk) 01:20, 29 April 2007 (UTC)
thread_title:  Its more like pcp 

message: Dosage of DXM for recreational purposes is fairly inaccurate when measured purely by mg of DXM, and is most often noted by mg/kg. For someone weighing 113 kg, for example, 600mg is unlikely to cause profound dissociation, while 600mg would be very intense for someone weighing 68 kg.AudhumlaX (talk) 06:00, 8 December 2007 (UTC)
thread_title:  Regarding the Recreational Section 

message: This is an informative article; some good work has been put into it! :-)
Just a note: a WP:LEDE should be placed before the TOC, and should summarize the article. Please see WP:LEDE for its appropriate nature and location.
Ling.Nut 13:54, 28 July 2007 (UTC)
replies: text: Thanks. There were many others involved of course, but speaking for everyone, thanks for the compliment :) Equazcion (Talk • Contribs) 14:01, 28 July 2007 (UTC)

text: *Threw something together, very short for now but I'll be working on it more. Thanks for the advice :) Equazcion (Talk • Contribs) 07:03, 29 July 2007 (UTC)
thread_title:  Good work! .. needs a [[WP:LEDE]] 

message: I have taken Dextroverse off the external links, it is a website glorifying drug abuse and doesn't contain accurate or useful information about dextromethorphan.  If this website should be linked anywhere it would be in an article about the phenomenon of IRC servers and forums used by teenagers to brag about their dangerous abuse of over-the-counter drugs, especially the deadly coricidin which has been linked to most dxm-related deaths.  It was either put on here by someone who didn't know what it was about or by a member of the place itself looking to advertise.  —The preceding unsigned comment was added by 68.118.76.8 (talk) 22:42, August 20, 2007 (UTC) 
:I think it should probably stay in the article. External links aren't references, they're just portals to further information. They don't need to be 100% neutral referenceable material. Dextroverse is a prominent site and it's important to understanding recreational DXM use as a cultural phenomenon. Equazcion (Talk • Contribs) 22:59, 20 August 2007 (UTC)
replies: text: I second it staying in the article.  I used to post on the forums there and a lot of intelligent discussion does occur.  In the future, please have some tolerance for lifestyle choices that differ from your own.68.211.162.60 (talk) 20:54, 19 December 2007 (UTC)

text: I also support it staying, it's a comprehensive DXM website, and also is on the first page of a Google search of 'DXM'. --Mark PEA (talk) 23:50, 20 December 2007 (UTC)

text: Just cause you disagree with some peoples lifestyles does not mean in should be taken off, it has further information for dextromethorphan.71.126.103.8 (talk) 02:36, 23 December 2007 (UTC)
thread_title:  Dextroverse