Talk:Butalbital/acetaminophen

message: Hmm -- the caption for the Fioricet picture says it's the generic; those pills look suspiciously like name-brand Fioricet.  The generics, as far as I know, are white and tab-shaped.
There are are actually generic blue tablets. for complete information and images see http://www.drugdigest.org/DD/PillImages/PillImagesSearch/1,20327,,00.html
*the TEVA (west-ward) version of the generic is blue eLeigh33 23:07, 29 March 2007 (UTC)
thread_title:  picture says it's the generic but looks like Fioricet 

message: Should butalbital-containing analgesics be banned? Yes.
Young WB, Siow HC.
Jefferson Headache Center, Department of Neurology, Thomas Jefferson University, 111 South 11th Street, Philadelphia, PA 19107, USA. William.B.Young@mail.tju.edu 
Curr Pain Headache Rep. 2002 Apr;6(2):151-5. 
Abstract
In the United States analgesic-overuse headache is often caused by butalbital-containing analgesics. These agents can cause physical and psychological dependency, and dangerous withdrawal syndromes. Butalbital-containing analgesics have already been banned in several European countries. They are proven effective in tension-type headache, but not in migraine; there are many alternative treatments for migraine and tension-type headache. In the 20 years since analgesic overuse headache was widely recognized, butalbital overuse has remained distressingly common. It is time to ban these agents.
  — Preceding unsigned comment added by 99.190.133.143 (talk) 17:58, 23 October 2011 (UTC)
thread_title:  Should butalbital-containing analgesics be banned? Yes. {{PMID|1187287}}  

message: Do butalbital-containing products have a role in the management of migraine? 
Pharmacotherapy. 2002 Aug;22(8):1029-35.
Wenzel RG, Sarvis CA.  Diamond Headache Clinic Inpatient Unit, St. Joseph Hospital, Resurrection Health Care, Chicago, IL 60657, USA. rwenz@hotmail.com
http://www.ncbi.nlm.nih.gov/pubmed/12173787  — Preceding unsigned comment added by 99.190.133.143 (talk) 18:00, 23 October 2011 (UTC)
thread_title:  Do butalbital-containing products have a role in the management of migraine? [No] {{PMID|12173787}} 

message: Butalbital in the treatment of headache: history, pharmacology, and efficacy.
Headache. 2001 Nov-Dec;41(10):953-67.
Silberstein SD, McCrory DC. 
Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA.
Abstract
Analgesics containing butalbital compounded with aspirin, acetaminophen, and/or caffeine are widely used for the treatment of migraine and tension-type headache. The butalbital-containing compounds are efficacious in placebo-controlled trials among patients with episodic tension-type headaches. Despite their frequent clinical use for migraine, they have not been studied in placebo-controlled trials among patients with migraine. Barbiturates can produce intoxication, hangover, tolerance, dependence, and toxicity. Butalbital can result in intoxication that is clinically indistinguishable from that produced by alcohol. Butalbital-containing analgesics can produce drug-induced headache in addition to tolerance and dependence. Higher doses can produce withdrawal syndromes after discontinuation. Butalbital-containing analgesics may be effective as backup medications or when other medications are ineffective or cannot be used. Because of concerns about overuse, medication-overuse headache, and withdrawal, their use should be limited and carefully monitored.
  — Preceding unsigned comment added by 99.190.133.143 (talk) 18:01, 23 October 2011 (UTC)
thread_title:  Butalbital in the treatment of headache: history, pharmacology, and efficacy.  {{PMID|11903523}} 

message: … The use of analgesics containing Butalbital is controversial to say the least. Analgesics with barbiturates such as Butalbital are banned in Germany, and expert advisory panels elsewhere have warned of their potential for abuse.2,3 Some experts warn that butalbital is particularly likely to lead to rebound (analgesic overuse) headache and/or dependence and question whether their benefit outweighs these problems.3 The authors comment:
http://headaches.about.com/cs/druginfo/a/fiorinal_care.htm
[Part of a larger article]  — Preceding unsigned comment added by 99.190.133.143 (talk) 18:04, 23 October 2011 (UTC)
thread_title:  Analgesics with barbiturates such as Butalbital are banned in Germany 

message: Resources:
Silberstein, Stephen D. & McCrory, Douglas C. (2001) "Butalbital in the Treatment of Headache: History, Pharmacology, and Efficacy." Headache: The Journal of Head and Face Pain 41 (10), 953-967.  Available from: http://dx.doi.org/10.1046/j.1526-4610.2001.01189.x [$] [Free synopsis http://www.ncbi.nlm.nih.gov/pubmed/11903523] 
2 Sellers EM, Hoornweg K, Busto UE, Romach MK. Risk of drug dependence and abuse posed by barbiturate-containing analgesics. Can J Clin Pharmacol. 1999;6:18-25.
3 McLean W, Boucher EA, Brennan M, et al. Is there an indication for the use of barbiturate-containing analgesic agents in the treatment of pain? Guidelines for their safe use and withdrawal management. Can J Clin Pharmacol. 2000;7:191-197.
4 Ciraulo DA & Greenblatt DJ. Sedative-, hypnotic-, or anxiolytic-related disorders. In: Kaplan HI, Sadock BJ, eds. Comprehensive Textbook of Psychiatry. 6th ed. Baltimore: Williams & Wilkins; 1995:872-887.
5 Sullivan JT & Sellers EM. Treatment of the barbiturate abstinence syndrome. Med J Aust. 1986;145:456-458.
6 Fraser HF, Wikier A, Essig CF, Isbell H. Degree of physical dependence induced by secobarbital or pentobarbital. JAMA. 1958;166:126-129.
7 Sullivan JT & Sellers EM. Treatment of the barbiturate abstinence syndrome. Med J Aust. 1986;145:456-458.  — Preceding unsigned comment added by 99.190.133.143 (talk) 18:06, 23 October 2011 (UTC)
thread_title:  Citation of a number of scientific authorities emphasizing risk of drug dependence and abuse posed by barbiturate-containing analgesics 

message: Am J Pharm Educ. 2010 February 10; 74(1): 4. 
Didactic Migraine Education in US Doctor of Pharmacy Programs 
... 
:CONCLUSIONS
"Although the majority of PharmD programs teach information consistent with the US Consortium's recommendations, opportunities exist to improve didactic migraine education. Particular attention should be directed towards expanded dissemination of evidence-based care, the rational selection of nonprescription versus prescription products, risks of butalbital-containing products and narcotics, and tools to assess migraine-related debilitation. 
Full article
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829152/?tool=pubmed
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829152/?tool=pubmed  — Preceding unsigned comment added by Ocdnctx (talk • contribs) 13:20, 15 August 2012 (UTC)
thread_title:  PMC article examining failure to follow evidence-based guidelines relegating butalbitol to 2d tier or below for migraine 

message: Fioricet is simply the brand name for a butalbital combination.  It is available as a generic, and does not merit a separate article.  This separate article amounts to advertising for the proprietary name. 
The separate Fioricet article should be merged into a combined discussion of butalbital combinations in single section of the butalbitol article 
 comment added by Ocdnctx (talk • contribs) 15:01, 15 August 2012 (UTC)
thread_title:  Fioricet article should be merged into a combined discussion of butalbital combinations in single discussion in the butalbitol article  

message: Fioricet's website states that they are exempt from schedule 3 status. http://www.fioricet.com/ source, and here's a quote from the website:
"Contains 50 mg butalbital, 300 mg acetaminophen, and 40 mg caffeine.2
    The FDA has designated Fioricet® with 300 mg of acetaminophen as having the same therapeutic effect as the discontinued product, which contained 325 mg of acetaminophen3
    Fioricet® has received exempted prescription drug status from the DEA and is no longer regulated as a CIII product3"
I suppose they could be wrong about it, but I just wanted to share that bit of info.  ~~  — Preceding unsigned comment added by 65.118.16.36 (talk) 17:34, 28 December 2013 (UTC)
thread_title:  ''new'' Fioricet schedulling 

message: Two months ago this was $33. Last month $39. I just priced all local pharmacies and got prices from $49-$440. What is going on  Dfrees (talk) 18:17, 25 October 2016 (UTC)
thread_title:  Cost of fiorect