Talk:Blinded experiment

message: Does anyone know who carried out the first true double blind trial and thus invented the methodology?
Noel jackson. LIFE.Newcastle
*Suggest merging Blinding (medicine) into this topic.  I also want to add references to the scientific method,  social sciences, psychology, and the physical sciences.  Blinding is not just important in medical clinical trials, its important in all sciences.  I had considered creating a topic Blinding (scientific method) and merging both into it, but Double-blind is already a pretty good topic and its the term most people would use when searching for information. Thatcher131 07:53, 11 February 2006 (UTC)
thread_title: Untitled

message: Is there no controversy or questioning of the validity of blinded studies?   What about human subjects being able to guess if they were in the active drug group, and that affecting the results?   This is a big enough issue that the statistics of some studies are recalculated or seriously questioned...  There must be some criticisms of blinded studies..?  --159.178.248.49 (talk) 13:18, 15 March 2010 (UTC)
thread_title:  controversy 

message: For the risk of being laughed at. Is there any proof that mice experiments are not influenced by placebo effect. I can imagine the lab staff talking to the doomed mice "here you buggers, eat this, you will all die soon anyhow." and to the lucky mice "look over to you neighbors, they're gonna die soon, you are the lucky ones". And maybe the mice understand ? If not word for word, but maybe body language.
Is double blind method being used with mice experiments ?
-- Paparodo, dec 13th 2006 —The preceding unsigned comment was added by 217.10.60.85 (talk) 11:46, 13 December 2006 (UTC)
thread_title:  Placebo & mice 

message: Does anyone know if there was a double-blind study where BOTH groups were given a placebo, but both were told that one group was getting a med and one was not?  Did anyone measure what is the % of success of placebo group that is always reported by a placebo group in a double-blind study.
What I am looking for is a percent of success reported from the placebo group? 
Was there such study?  
Can someone post that?
Thanks.
Atessitore05 13:50, 13 December 2006 (UTC)
replies: text: I doubt there's any single number. Successful outcomes in either group (control and test) can potentially range anywhere from none to all. Given the variety of therapies being tested, and the conditions being studied, would you expect success to even be defined the same way, much less measured at a consistent rate? At any rate, the article on the placebo effect is probably a good place for you to look for more information. In fact I found this there: "...studies generally do not include an untreated group, so determining the actual size of the placebo effect, compared to totally untreated patients, is difficult...", and, again, not likely to yield similar results across dissimilar studies. 198.49.180.40 22:05, 5 April 2007 (UTC)
thread_title:  Double placebo numbers  

message: when an experimenter tells the subject that something is X but then switches X with Y in order to observe the existence of the subject's bias? does it have a name? --AnY FOUR! 04:46, 4 August 2007 (UTC)
thread_title:  What's it called... 

message: I'm an ex-subjective audio reviewer (Stereophile) who's had terrible arguments with Arny Krueger, et al, about problems with controlled testing -- namely, that listening under controlled conditions is not the same as listening casually (which is how we actually listen to music). This point -- that controlling the test conditions can also alter them -- needs discussion.
WilliamSommerwerck (talk) 14:57, 15 February 2008 (UTC)
thread_title: ABX testing

message: Blinding is far from ubiquitous in the scientific method.  It is relatively rare in chemistry, physics, geology, meteorology, astronomy, and forensic science.  It is even relatively rare in many areas of biology and medicine.  I recently reviewed a number of grant proposals related to traumatic brain injury; less than 10% included blinding in their proposed methods. 
Michael Courtney (talk) 11:45, 1 April 2008 (UTC)
replies: text: You're right.   Blinded trials seem to be most used to test if a drug has a measurable effect against something else (placebo, another drug, etc.)   In this kind of testing situation it is ubiquitous, but otherwise not so much...  --159.178.248.49 (talk) 13:15, 15 March 2010 (UTC)
thread_title: Not ubiquitous

message: I think the reference:
"Male circumcision 'cuts' HIV risk" ... Retrieved on 2009-05-18. 
is not related to blind experiment at all.
1. All the males knew about their circumcision and were equally informed about safe sexual behavior...
2. The experiment was a social behavior study with no intervention from the researcher's side concerning participants' conditions. 
I agree male social behavior can be seen as a kind of blind activity if not under a supervision in general ;), but hey, in blind experiment we have to actively make a difference and at the same time we do hide the difference to participants or even researchers to avoid bias...
Even if researchers performed circumcision on half of the group it would not have been a blind experiment.
(btw. I do not think the experiment is correct concerning possible corellation between circumcision and safe sexual behavior - it is pretty logical to assume that people comming from society where it is usual to perform circumcision - i.e. society taking care about "these issues" - will take more care... If a father sends his boy to a tribal medicine man for circumcision, he will more probably also teach him how to avoid HIV)
I would rather remove all the note concerning ethical troubles. The note is valid for experiments in general - once we know the result and it can safely help we should use it for wide public if possible. Does not matter whether it is a blind experiment or not...
--213.160.184.124 (talk) 11:44, 16 June 2009 (UTC)
thread_title: Male circumcision 'cuts' HIV risk - not a blind experiment at all

message: The lead of the article mention triple-blind experiments and says that more will be discussed later in the article, but triple-blind experiments are never mentioned again in the article. Can somebody add information about what a triple-blind experiment is? --Bando26 (talk) 06:20, 30 August 2009 (UTC)
thread_title:  Triple-blind 

message: I believe this is "double blind," and not "double-blind." The latter refers to the adjectival form only, as, by WordNet, "a test procedure in which the identity of those receiving the intervention is concealed from both the administrators and the subjects until after the test is completed; designed to reduce or eliminate bias in the results."  —Preceding unsigned comment added by Twipley (talk • contribs) 23:59, 3 November 2009 (UTC)
thread_title:  ortography 

message: This same technique is used in elections and IT (crypto particularly), perhaps the uses section could be expanded to include those.
I'd suggest that blind experiments are one application of a more general technique. — Preceding unsigned comment added by 77.86.117.208 (talk) 09:50, 8 August 2018 (UTC)
thread_title:  Blinding, Experiments and other uses