lflage/wiki-talks huggingface dataset:
Talk:Love rose

message: How is this article related in any way to Pharmacology?? OlEnglish (talk) 23:55, 3 December 2008 (UTC)
replies: text: the article is about a crack pipe. to me, that sounds drug related. badmachine (talk) 23:29, 31 May 2009 (UTC)
thread_title: Pharmacology Wikiproject??
Talk:Loxapine

message: "The typical dosage is 2 drops twice daily."
Well, two drops of what? I presume, of drops/oral solution/guttae, but of what concentration? If the oral soln is of 1 mg/mL, 2 drops would be probably 0.1 mg of active substance. If the oral soln is of 100 mg/mL, then 2 drops would correspond to 10 mg active substance. Both concentrations are common for neuroleptics/antipsychotics oral solutions. I'll try to find some more conventional dosage data, preferably in mg/die.--Spiperon 14:12, 1 May 2007 (UTC)
thread_title:  Dosage? 

message: Well? Why no mention of this in the article?
75.93.149.42 (talk) 17:25, 19 April 2012 (UTC)
thread_title:  [[Schizoaffective disorder]] 
Talk:Lubiprostone

message: There should be only 5 carbons at the side chain of 1,1-difluoropentyl. And the formula of lubiprostone only 20 carbons, but the structure shows 21 carbons.  —Preceding unsigned comment added by 211.78.179.120 (talk) 15:24, 9 March 2008 (UTC)
replies: text: The current structure is correct.  ChemNerd (talk) 20:34, 13 March 2012 (UTC)
thread_title:  There is a wrong structure in the article of lubiprostone. 

message: why have we no mention of the fact that, according to the official website, the drug is approved only for use in women? Toyokuni3 (talk) 15:58, 1 July 2011 (UTC)
thread_title: Indications
Talk:No-wandering-domain theorem

message: Im not really great yet with the wiki syntax, but I
belive that this theorem is very important in this field, 
and is one of the most important proofs in complex dynamics.
Paxinum 20:35, 1 March 2007 (UTC)
replies: text: OK, but the mathematician who proved it (Dennis Sulivan) already had a wikipedia article.  So I put the link to that page, and added some relevant info.  I will also redirect the D. Sullivan page to Dennis Sullivan, and move the content there.  Hope this will do it. Turgidson 03:05, 2 March 2007 (UTC)

text: Fair enough (about the notation), especially since you have now explained it. -- Jitse Niesen (talk) 03:14, 3 March 2007 (UTC)
thread_title:  Not yet 

message: The caption on the image shown reads like this:
"This image illustrates the dynamics of ; the Fatou set (consisting entirely of wandering domains) is shown in white, while the Julia set is shown in tones of gray."
The dynamics of what???  I don't think anything is wrong with the sentence structure or the punctuation; there's just a missing word right before the semicolon.  I'd fill it in, except I have no idea what it should be.2600:6C50:800:2787:4544:D3E8:A5C4:D2D0 (talk) 16:11, 26 March 2022 (UTC)
thread_title:  Missing caption
Talk:Mapatumumab

message: Is this permitted ? It seems unusual and unbalanced.
Some of the earlier ones are probably no longer important ?
Intro could do with a summary of the current status. Rod57 (talk) 02:44, 25 March 2010 (UTC)
replies: text: Did some pruning, but this article needs much more work until it is acceptable. --ἀνυπόδητος (talk) 10:02, 25 March 2010 (UTC)

text: Looks better now, I think. --ἀνυπόδητος (talk) 09:40, 17 June 2010 (UTC)
replies: text: Yes, much better. Rod57 (talk) 08:59, 2 July 2010 (UTC)
thread_title:  Long list of press releases
Talk:Mast cell stabilizer

message: The article in its present for has a long list of example medications that for the most part are not supported by the sources, and are in fact contradicted by the sources. There seems to have been attempts to fix this in the past, but they were reverted, so I am going to present a case here before I fix them. (Though I suspect the reversions had something to do with the bad formatting used in the fix?)
The current list contains:
* β2-adrenergic agonists
* Cromoglicic acid
* Ketotifen
* Loratadine
* Desloratadine
* Methylxanthines
* Olopatadine
* Rupatadine
* Mepolizumab
* Omalizumab
* Pemirolast
* Quercetin
* Nedocromil
* Azelastine
* Tranilast
* Palmitoylethanolamide
* Vitamin D
* Bilastine
Of these, only the last, Bilastine, has a source, but that source seems to actually be talking about Vitamin D, though I can't read the entire paper as it is behind a pay wall. Most of the medications on this list are allergy medications, and I believe they were put here based on the confused assumption that all allergy medications are mast cell stabilizers, which is not true. The current first source lists many of these medications, but only Cromolyn (aka Cromoglicic acid), Lodoxamide, and Nedocromil are listed as mast cell stabilizers. A cursory look at some other sources    suggests that the list is in fact pretty short in terms of drugs, but that there are other compounds that also seem to stabilize mast cells.
The previous reverted fix listed:
Cromolyn ( or cromoglycate)
Nedocromil
Ketotifen
and additionally listed
β2-adrenergic agonists: Salbutamol, and
Methylxanthines: Theophylline
The addition of β2-adrenergic agonists makes some sense, I suppose, as I believe they are mast cell inhibitors, but the Methylxanthines makes me pretty sure that these last two categories were added based on the assumption that asthma medications were all mast cell stabilizers, which is also not true.
Generally I prefer not to do unilateral changes without dialogue, especially in areas that aren't my expertise, but given that nothing is sourced, and this article receives very little attention, I'm going to cut the list down to only those I can find sources for, and invite someone more experienced than I to expand upon that list if possible. naturalnumber (talk) 02:37, 3 April 2023 (UTC)
thread_title:  Examples are cited and most likely wrong 

message: Loratadine ketotifen quercetin should be put back on there 82.36.88.144 (talk) 18:35, 16 August 2023 (UTC)
thread_title:  Why have you removed examples of Mast 

message: There is proof that Quercetin is a stronger mast cell stabilizer than sodium cromoglycate and there is proof of Desloratadine having mast cell stabilising properties. 
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1398-9995.2004.00641.x#:~:text=Conclusions%3A%20Desloratadine%20may%20have%20a,mast%20cell%20activation%20in%20vitro.
https://pubmed.ncbi.nlm.nih.gov/22470478/ 82.36.88.144 (talk) 17:58, 23 August 2023 (UTC)
thread_title:  The previous editor was wrong.
Talk:Herman Yau

message: Prior content in this article duplicated one or more previously published sources. The material was copied from: https://web.archive.org/web/20061027112055/http://www.hermanyau.com/eabout.htm. Copied or closely paraphrased material has been rewritten or removed and must not be restored, unless it is duly released under a compatible license. (For more information, please see "using copyrighted works from others" if you are not the copyright holder of this material, or "donating copyrighted materials" if you are.)
For legal reasons, we cannot accept copyrighted text or images borrowed from other web sites or published material; such additions will be deleted. Contributors may use copyrighted publications as a source of information, and, if allowed under fair use, may copy sentences and phrases, provided they are included in quotation marks and referenced properly. The material may also be rewritten, providing it does not infringe on the copyright of the original or plagiarize from that source. Therefore, such paraphrased portions must provide their source. Please see our guideline on non-free text for how to properly implement limited quotations of copyrighted text. Wikipedia takes copyright violations very seriously, and persistent violators will be blocked from editing. While we appreciate contributions, we must require all contributors to understand and comply with these policies. Thank you.  Yeeno  (talk) 🍁 22:03, 30 January 2022 (UTC)
thread_title:  Copyright problem removed
Talk:Mebeverine

message: Having tried every imaginable drug/supplement for IBS, largely in vain, I have found mebeverine (a.k.a. Colofac IBS, available only online from the UK) to be a godsend, taken as 1 tablet 20 minutes before each meal. It is also crucial to google the IBS diet and try to identify one's personal trigger foods. Finally, soluble fiber in the form of FOODS, not fiber supplements, is at least as important as the drug. Meditrix (talk) 22:03, 17 October 2008 (UTC)
thread_title: Note

message: Please accept the edits to this page (February 14, 2013). My name is Scott Stoffel, and I work at Abbott Laboratories in Corporate Public Affairs, and the edits I am providing are all factual, based upon review of the page with Abbott Laboratories scientists who have expertise in this area. If you have questions, please do not hesitate to access my contact information, found here: http://abbott.com/news-media/contacts.htm  — Preceding unsigned comment added by ScottStoffelAbbott (talk • contribs) 18:36, 14 February 2013 (UTC)
thread_title:  Abbott Laboratories 

message: If it is antimuscarinic, can we say it is 'without anticholinergic side-effects' as it stands in the article? 77.93.29.14 (talk) 17:20, 23 July 2015 (UTC)
thread_title:  Anticholinergic side-effects 

message: User:Karol Langner about this.  I agree that this article probably doesn't need any sections at all.  I feel that people generally overuse sectioning.  But to the extent that we are using them, this should follow the structure described for drugs in WP:MEDMOS.  I often collapse brief articles like this but people end up putting the sections back, so I generally don't fuss over it. Jytdog (talk) 15:33, 21 June 2018 (UTC)
replies: text: Got it, Jytdog. I don't have strong feelings about sections, but my edit improved (I believe) more than just sectioning. Karol (talk) 15:37, 21 June 2018 (UTC)
replies: text: I think this article would be better with no sections.  It is brief enough.  I doubt this would be sustained though -- people will come back and start adding them in again.  We can try it if you like but we shouldn't raise  a ruckus if people restore them....Jytdog (talk) 15:41, 21 June 2018 (UTC)
replies: text: Like I said, I don't have strong feelings about the sections, my point was that I improved the wording (in my mind) a lot, and the text read much better after my edit. Jytdog, if you restore my version, I can shorten the intro or get rid of all sections, whichever you think makes more sense. Either way, this was just a drive-by edit, I actually got here via the 'random article' link :D Karol (talk) 11:08, 23 June 2018 (UTC)
thread_title:  Condensing
Talk:Reactor operator

message: Control Room Operator?  I am unfamiliar with this term as defined by the NRC.  While manipulation of the controls is allowed by a trainee under the direct supervision... etc etc (See 10CFR-55 for more info if desired),  such a person is just a trainee.  There is no special regulatory title for this person.  I'll change it for now and can discuss if desired. I will provide the trainee text from 10CFR at the bottom of the section. Alfredo22 20:40, 1 March 2007 (UTC)
Talk:Albinus of Angers

message: The recent tags on lack of sources does not make sense. In sources, John Dodd's scholarly notes on the period of Albinus (Aubin) and his translation of the life from Latin seem to provide an extremely firm support for grounding the article in references.
--TonyinJersey 09:37, 5 March 2007 (UTC)
thread_title:  Recent Tags
Talk:Meglumine antimoniate

message: Roberts et al. () suggest that meglumine antimonate is a complex mixture. I've rendered a ball-and-stick model of the purported major component, and might add that to the article. Does anyone have any thoughts? Fvasconcellos (t·c) 23:35, 8 July 2007 (UTC)
replies: text: Added. If there are any objections, please feel free to comment here. Fvasconcellos (t·c) 16:36, 19 July 2007 (UTC)
thread_title:  Structure
Talk:Major Deegan Expressway

message: Why don't articles on highways and major roads include maps of the road in question? Not just maps of the surrounding state or county, but the road itself! Saying that a road is located in so-and-so city, or listing the exits just isn't as useful!
Klausner (talk) 05:26, 15 February 2010 (UTC)
replies: text: Because someone has to make them. Maps (especially quality ones with a free license) don't grow on trees. If you or anyone else would like to help with this effort, check out Wikipedia:WikiProject Maps. —D. Monack talk 06:18, 15 February 2010 (UTC)
thread_title:  Maps 

message: I think it would make sense to merge this artice with Interstate 87 (New York) since all of the Major Deegan is overlapped with I-87. I mean, there’s no article for the Adirondack Northway, and there’s a small part of that highway that’s not even part of I-87.  — Preceding unsigned comment added by 24.228.135.248 (talk) 20:24, 21 December 2018 (UTC)
thread_title:  Merge with [[Interstate 87 (New York)]]?
Talk:Melittin

message: The protein sequence is GIGAVLKVLTTGLPALISWIKRKRQQ John Moser (talk) 12:39, 27 May 2019 (UTC)
replies: text: Thanks, but is already linked via PubChem link, see https://pubchem.ncbi.nlm.nih.gov/compound/16133648#section=Biologic-Description  KR 17387349L8764 (talk) 14:59, 30 June 2021 (UTC)
thread_title:  Protein sequence 

message: It's early days, of course, but it seems melittin might work as a chemo agent for some lung and breast cancers.
https://www.sciencealert.com/bees-formidable-weapons-could-successfully-target-aggressive-breast-cancer
203.13.3.89 (talk) 03:22, 4 September 2020 (UTC)
replies: text: Yes, a number of research sources exist, see for example https://pubmed.ncbi.nlm.nih.gov/?term=melittin+tumor&filter=years.2015-2021 or https://www.sciencedirect.com/search?qs=melittin%20tumor ... you could add it if you specifically write about it and add specific references, but the topic seems not so new and probably can be extended to various other peptides or the general research into peptides and applications. Sciencealert is always full of hyper stuff, I recommend equalizing it accordingly. BR  17387349L8764 (talk) 15:05, 30 June 2021 (UTC)
thread_title:  Potential cancer treatment 

message: The research is limited? Does ref 7 proof this in particular? I see a stable research on-going. See for example https://pubmed.ncbi.nlm.nih.gov/?term=melittin, or the yearly publication numbers https://www.sciencedirect.com/search?qs=melittin. Maybe the tumor-related research is limited, but the meaning is different and has to be made clear. The paper (ref 7) also reads "non-specific cytotoxicity and hemolytic activity". BR  17387349L8764 (talk) 15:15, 30 June 2021 (UTC)
replies: text: All preliminary research too early-stage to discuss, with no rigorous clinical research published to date. Needs a WP:MEDRS review for the encyclopedia (note: no such review exists). Zefr (talk) 16:35, 30 June 2021 (UTC)
thread_title:  limited scientific research on its potential effects 

message: This form of 89.198.64.100 (talk) 17:10, 3 September 2022 (UTC)
thread_title:  Meleten
Talk:Sorafenib

message: HCC Patient on Sorafenib Develops Two Nodules says 
:"Cutaneous toxicity, however, is relatively common, perhaps even approaching 90%, in patients receiving this medication. The most frequent skin side effects include: a nonspecific maculopapular rash (34%), hand-foot syndrome (27% to 60%), initial appearance or worsening of psoriasis, facial erythema with or without edema, erythema multiforme, subungual splinter hemorrhages, stomatitis, alopecia, xerosis, eruptive nevi, inflammation of existent seborrheic keratoses, and induction of premalignant and malignant skin tumors.[4,5] Since the first report of sorafenib-associated squamous cell carcinoma in 2006,[6] about 50 patients have been reported to demonstrate cutaneous lesions with epithelial (epidermal) atypia, including an unmasking of numerous actinic keratoses, appearance of the classic keratoacanthoma subtype of squamous cell carcinoma, and development of classic ulcerated nodules of invasive squamous cell carcinoma." and
:"it is noteworthy that other multikinase inhibitor agents that share a similar mechanism of action do not share this relatively high predisposition toward inducing cutaneous neoplasms." - Rod57 (talk) 23:57, 10 October 2011 (UTC)
thread_title:  Common skin side effects 

message: Most of the footnotes add nothing - none of the side effects have a source, and which of the rare side effects are notable ? - how do they compare with the control groups ? Could delete the footnotes and the lower half of the section, and mark as needing RS ? - Rod57 (talk) 14:25, 7 July 2017 (UTC)
replies: text: Agree. Both the uncurated list of side effects and footnoting are inappropriate. Dr G (talk) 18:27, 29 December 2017 (UTC)
thread_title:  Adverse effects section seems excessive 

message: The 2D structure in the box is incorrect, while the 3D structure is fine. The pyridine nitrogen should be moved to the position oposite to the phenolic oxygen. 147.231.120.62 (talk) 14:56, 27 October 2023 (UTC)
thread_title:  Structure in the box is incorrect
Talk:Revolutionary Communist Youth (Sweden)

message: Revolutionary Communist Youth is an menber of called World federation of democratic youth it think. I am not sure But if they are how do you edit the page and make  an link in the box to the right that says intenational afflitations or something???
:I'm not sure. At least like 1-2 years back they weren't. --Soman 12:10, 14 March 2007 (UTC)
replies: text: You're probably confusing it with Communist Youth of Sweden, which displays the WFDY logo prominently on their website. Jobjörn (Talk ° contribs) 12:33, 14 March 2007 (UTC)
thread_title: RCY
Talk:Mepolizumab

message: This medication and related hypereosinophilic syndrome was mentioned in the "Nine Lives" episode of NCIS (TV series)  —Preceding unsigned comment added by 76.31.180.104 (talk) 06:19, 27 February 2009 (UTC)
thread_title: Mention in TV series

message: The redirect IL-5 antibody has been listed at redirects for discussion to determine whether its use and function meets the redirect guidelines. Readers of this page are welcome to comment on this redirect at  until a consensus is reached.  (t · c) buidhe 03:46, 4 December 2023 (UTC)
thread_title:  "[[:IL-5 antibody]]" listed at [[Wikipedia:Redirects for discussion|Redirects for discussion]]
Talk:Mesna

message: In the page for Cytoxan I found this: "Mesna is a sulfhydryl donor and binds acrolein.". Perhaps this should be included in the "Mechanism" section? 76.119.233.105 (talk) 21:23, 17 October 2009 (UTC)
thread_title: Mechanism

message: The article currently states that mesna "is administered intravenously, but oral dosing has been investigated.[2]"  The cited reference is from 2003, but I was in chemotherapy in 2000-01 and was given mesna orally.  Perhaps someone conversant with medical research could expand or update the discussion of this point. JamesMLane t c 19:35, 3 February 2011 (UTC)
thread_title: Oral administration
Talk:Pantothenate kinase-associated neurodegeneration

message: The name Hallervorden-Spatz syndrome has fallen from favour because Hallervoden and Spatz were Nazis that were complicit in the genocide that they committed. Also, that article is less substantial. Finally, there needs to be something about the movement to change the name. I'll do all this when I have time in the next week or so, unless someone else could beat me to it? RupertMillard (Talk) 20:55, 1 March 2007 (UTC)
replies: text: I've done this now. RupertMillard (Talk) 12:30, 18 March 2007 (UTC)
thread_title:  Merge from Hallervorden-Spatz syndrome 

message: eMedicine link is garbled, fix it please. Cheers, --CopperKettle 22:13, 18 December 2009 (UTC)
thread_title: eMedicine

message: is this the condition that was put forward by an Italian doctor in recent years as "cause" of multiple sclerosis?74.12.126.169 (talk) 14:32, 27 March 2018 (UTC)
thread_title:  "cause" of MS?
Talk:Kus

message: Is it good image :Image:Mehter kos drum.jpg for the article? I am not familiar with mucical terminology. --Snek01 20:58, 1 March 2007 (UTC)
thread_title: Image?

message: What is the Greek word Plutarch uses to describe the kus? 173.89.236.187 (talk) 22:29, 4 August 2015 (UTC)
thread_title:  Plutarch
Talk:Metyrapone

message: Good evening! Would it be okay to add a mention of the drug's role in the treatment of depression? There's one review (PMID 23983967) dedicated to this usage of metyparone (published in 2012), and one article in a book (published in 2019) that briefly mentions the use of metyparone in depression (Lazar & McIntyre, "Chapter 34 - Novel Therapeutic Targets for Major Depressive Disorder"). Are these good secondary sources? --CopperKettle 16:34, 1 May 2020 (UTC)
thread_title:  Investigational role in depression
Talk:Midodrine

message: how could it be alpha 1 agonist and increases blood pressure at the same time?
Answer:
alpha 1 agonists produce systemic vasoconstriction, they constrict both arteries and veins therefor they increase blood pressure.
Link title
You can read more from here
--Xhuman (talk) 10:58, 25 June 2009 (UTC)
thread_title: a paradox

message: Partial Ejaculatory Incompetence Study68.73.192.140 (talk) 18:53, 27 August 2011 (UTC)
thread_title: Another Indication

message: I could only find a single good recent source, doi:10.1016/j.jcrc.2013.05.021 which was a single-centre case series. This quote needs a strong secondary source to be worthy of inclusion. JFW | T@lk 18:20, 12 October 2014 (UTC)
thread_title:  Removed 

message: The following page links to two sources on midodrine (#14 and #15 in permalink): https://en.wikipedia.org/w/index.php?title=Orthostatic_hypotension&oldid=826528439#Pharmacological_management - maybe they can be used. --Treetear (talk) 01:53, 23 February 2018 (UTC)
thread_title:  Needs sources
Talk:Miltefosine

message: Below is our plan for editing particular sections on the wiki page. We are planning to review each section and individually add information we believe is missing. Teammates will make sure tract the changes via this talk page and/or resort to the revision history to see the changes others have made and make suggestions. We will also make a summary of what changes were made and/or information we would want other teammembers to know about on the revision history. 
Intro: ALL
Medical Use: Raymond
Side Effects: Sophia
History: Sophia
Future History: Victor and Liriany
Reference and Links: ALL
Lypimentel21 (talk) 20:43, 3 November 2016 (UTC)
thread_title:  Editing Plan  

message: STUDENT 1 - Does the draft submission reflect a neutral point of view? If not, specify. 
Yes, this article reflects a neutral point of view. It does not share one-sided opinions or personal stories. And no where in the article do the authors attempt to persuade the reader toward a certain view.Stella.lee (talk) 20:57, 15 November 2016 (UTC)
thread_title:  Peer Review (Group 17)
Talk:Raltegravir

message: How does the tetrazole heterocycle become an diazafuran heterocycle in the last step, which is only an amide synthesis?  —Preceding unsigned comment added by 92.138.251.174 (talk) 10:14, 28 March 2011 (UTC)
thread_title:  Synthesis 

message: As from December 2017, the recommended dose is either 400mg twice daily or 1200mg once daily. 
This section is not clear. Was the control group on raltegravir only or only on other antiretrovirals? If only on other antiretrovirals than it says that in Raltegravir group there twice as many viral copies than in control group, which makes it sound like raltegravir was elevating the viral load.
130.88.233.248 (talk) 08:37, 27 June 2011 (UTC)
thread_title:  Dosage 