Talk:Endomembrane system

message: I am an AP Biology student who is currently taking this article under my wing in the hopes that it will eventually reach Featured Article status.  This article achieved GA status on Christmas Eve, I'm setting my sights on FA. I welcome and encourage all who visit to contribute/criticize, albeit constructively, as they see fit.  If you see anything that you think should be changed than by all means let me know. I am completely open to suggestions and thankful for any help that might come from the Wikipedia community.
My end goal, as noted earlier, is to nominate and pass this article to Featured Article standing sometime in early March. While it will be a difficult road ahead, I hope those of you who took the time to read this will understand my undertaking and seek to help me expand and improve this article. Also, check out my user page to learn more about me or Wikipedia:WikiProject AP Biology 2008 for my AP Biology Class Goals/Project information. Cheers!
--VivaLaLacy (talk) 17:34, 7 September 2008 (UTC)
thread_title:  Help 

message: ==== History ====
# Brief History of the Cell
# History
==== Nuclear Envelope ====
# Nuclear Envelope UTMB
# Nuclear Envelope
# Nuclear Envelope Briticanna
# The arrangement of nuclear pore complexes in the nuclear envelope
# The Nuclear Envelope
# Nuclear Envelope Encyclopedia of Science
# What is the Nuclear Envelope?
# Nuclear Envelope - Need Password
# Dynamics of Nuclear Envelope Proteins During the Cell Cycle in Mammalian Cells
# The Nuclear Envelope and Traffic between the Nucleus and Cytoplasm
# 
==== Endoplasmic Reticulum ====
# Endoplamic Retiuculum
# Cell Anatomy: Endoplasmic Reticulum
# ER Cells Alive
# Endoplasmic Reticulum
# Endoplasmic Reticulum
# Endoplasmic Reticulum About.com
# Endoplasmic Reticulum - Need Password
# Endoplasmic reticulum stress and the development of diabetes - Need PasswordAbstract: Endoplasmic reticulum stress and the development of diabetes - Free Access
# How do proteins translocate into the lumen of the rough endoplasmic reticulum?
# Endoplamic Reticulum UTMB
# The Endoplasmic Reticulum
# The Endoplasmic Reticulum
# Ribosomes - Need Password
==== Golgi Apparatus ====
# Endomembrane System and Golgi Complex - Need Password
# Golgi Apparatus
# Golgi Complex UTMB
# Golgi Apparatus Cells Alive
# Golgi Apparatus Animated
# History of the Golgi Apparatus 
# The Golgi Apparatus in general
# The Golgi Apparatus
# Cell Anatomy: Golgi Apparatus
# Golgi Complex: Structure and Function
==== Vacuoles ====
# Cell Anatomy: Vacuole
# Vacuoles
# Vacuole
# Vacuoles# Vacuoles
==== Vesicles ====
# Vesicles
# Vesicles
# Molecular Mechanisms of Vesicular Traffic
# The Mechanism of Vesicular Transport
==== Lysosomes ====
# Lysosomes Are the Principal Sites of Intracellular Digestion
# Lysosomes
# Lysosomes UTMB
# Lysosomes Interactive
# Lysosomes PubMed
# Lysosomes Are Acidic Organelles
==== Cell Membrane ====
# Cell Membrane UTMB
# Cell Membrane Interactive
# Cell Membrane Interactive
# Plasma Membrane
# Plasma Membrane
# Cell Anatomy: Cell Membrane
# Cell Anatomy: Cell Wall
# Biomembranes: Structural Organization and Basic Functions
# Structure of the Plasma Membrane
# Plasma Membrane Function
# Campbell, Neil, and Jane Reece. Biology. 6th ed.
# "Cell" The World Book Encyclopdiea 2003 edition
# Endomembrane System Bio-Medicine
# Eukaryotic Cell
# Organelles of the Eukaryotic Cell
# The biology of the cell
# Organelles
# Eukaryotic Cells - Need Password
# Cytoplasm - Need Password
# Protein transport in the plant secretory pathway
# The endomembrane system and the problem of protein sorting. - free access
# The role of mRNA and protein sorting in seed storage protein synthesis, transport, and deposition1 - Need PasswordAbstract:The role of mRNA and protein sorting in seed storage protein synthesis, transport, and deposition1 - Free Access
# Protein transport in the plant secretory pathway1 - Need Password
# Membrane Dynamics in the Early Secretory Pathway - Need PasswordAbstract: Membrane Dynamics in the Early Secretory Pathway - Free Access
# Protein Transport in Plant Cells
# Center for Plant Cell Biology at UC Riverside
# Organelles
--VivaLaLacy (talk) 23:54, 2 October 2008 (UTC)
thread_title:  Potenetial Resources 

message: # Cell Membrane UTMB
# Cell Membrane Interactive
# Cell Membrane Interactive
# Plasma Membrane
# Plasma Membrane
# Cell Anatomy: Cell Membrane
# Cell Anatomy: Cell Wall
# Biomembranes: Structural Organization and Basic Functions
# Structure of the Plasma Membrane
# Plasma Membrane Function
# Campbell, Neil, and Jane Reece. Biology. 6th ed.
# "Cell" The World Book Encyclopdiea 2003 edition
# Endomembrane System Bio-Medicine
# Eukaryotic Cell
# Organelles of the Eukaryotic Cell
# The biology of the cell
# Organelles
# Eukaryotic Cells - Need Password
# Cytoplasm - Need Password
# Protein transport in the plant secretory pathway
# The endomembrane system and the problem of protein sorting. - free access
# The role of mRNA and protein sorting in seed storage protein synthesis, transport, and deposition1 - Need PasswordAbstract:The role of mRNA and protein sorting in seed storage protein synthesis, transport, and deposition1 - Free Access
# Protein transport in the plant secretory pathway1 - Need Password
# Membrane Dynamics in the Early Secretory Pathway - Need PasswordAbstract: Membrane Dynamics in the Early Secretory Pathway - Free Access
# Protein Transport in Plant Cells
# Center for Plant Cell Biology at UC Riverside
# Organelles
--VivaLaLacy (talk) 23:54, 2 October 2008 (UTC)
thread_title:  Cell Membrane 

message: Yea... a reputable reference in an acceptable format... I wish you were at the beginning of the alphabet!--JimmyButler (talk) 19:27, 4 October 2008 (UTC)
thread_title:  Citations 

message: Does anyone know the correct way to refernce an online book?  As you can see from my reference list on the article, the same books are appearing for the different parts of the endomembrane system.  I don't think it would be suffice to just reference the book once, because then you would lose all of the url's associated with the different sections of the book.  I'd like to keep the links to the different sections, because as an article on an online encylcopedia connectivity is crucial. --VivaLaLacy (talk) 22:12, 4 October 2008 (UTC)
replies: text: This can be done by separating (foot)notes from references. I've indicated the idea with a couple of examples. Geometry guy 23:33, 4 October 2008 (UTC)

text: I've now done the rest. Geometry guy 15:06, 5 October 2008 (UTC)
replies: text:  Thank you so much, In all of my upcoming sources I'll be sure to follow your format. --VivaLaLacy (talk) 20:27, 5 October 2008 (UTC)
replies: text: You're welcome. You may want to check that the weblinks all go where you want: with this format you can have a specific weblink for the cite, and a separate weblink for the general reference. Geometry guy 23:18, 5 October 2008 (UTC)
thread_title:  Reference Help 

message: I strongly recommend running your additions to this article through Microsoft Word and do a spell check. Nothing discredits an article like having your teacher correct spelling errors involving "standard" English words. If you activate the supplemental programs as suggested in class; the typo's will appear underlined in red. Remember you are writing a formal document with a world-wide audience; there is no tolerance for spelling errors. --JimmyButler (talk) 21:33, 26 October 2008 (UTC)
thread_title:  Spell Check 

message: * Create membrane section and explain overall structure and function - debatable 
* Explain captions thoroughly
* Set images the thumb width
* Justify more places with references 
* Expand the lead paragraph
* Copyedit
A major leap forward in content. If you do not wait to the last minute to address your peer review concerns; there is hope for GA before the grading period is over. Best of Luck!!!--JimmyButler (talk) 18:27, 30 November 2008 (UTC)
thread_title:  To Do 

message: For some reason reference 21 is not repeated in the paragraph that follows it.  Instead there is a separate reference number (22) for a reference that is the exact same.  Please help if you have the knowledge to do so.  --VivaLaLacy (talk) 03:45, 6 December 2008 (UTC)
thread_title:  Reference Help 

message: I am not quite sure about this but you have used the the citations 12 and 14 together, one right after the other (eight times in a row) and I believe this to be redundant and unneccesary. I feel that you should either get more citations to fill in these spots or just cite 12/14 at the end of the the entire unit (no–not each paragraph, the entire unit). 
--Cooldrummer (talk) 19:13, 29 December 2008 (UTC)
replies: text: The citations are placed there to meet requirments for the quantity of citations that I was told.  I felt that if they were not there people would raise concern over where that information came from.  I used those two sources for that information, so it would be unneccesary to use more citations to fill in those spots. If just citing 12 and 14 at the end of each unit is acceptable by citation standards then I will do it.  --VivaLaLacy (talk) 00:28, 30 December 2008 (UTC)
replies: text: The concern has been addressed well. Pardon my tight review.
--Cooldrummer (talk) 01:25, 30 December 2008 (UTC)

text: There was no problem with  citations. Cite after each sentence. Who cares if the same source is used ad infinitum, as long as it is a good source. Cheers! Wassupwestcoast (talk) 01:30, 30 December 2008 (UTC)
thread_title: Citations

message: I personally believe that this article needs more work for the spitzenkorper section because I do not fully understand what it is maybe some media or a better explanation would work. --AwesomeOpossuminthelake (talk) 19:37, 29 December 2008 (UTC)
replies: text: Honestly, I do not know much about this component of the endomembrane system.  User:Peter G Werner is the user that added this section.  If it is agreed that expansion to this needs to be made, I could request his help.  --VivaLaLacy (talk) 00:32, 30 December 2008 (UTC)
replies: text: , I think your being messed with.  The article Endomembrane system is an overview and doesn't need to expand a section that highlights a unique organelle in the fungi beyond a couple of sentences. The spitzenkörper section is fine as it is. Cheers! Wassupwestcoast (talk) 01:26, 30 December 2008 (UTC)
replies: text: My question has been answered very well. Thank you.
--Criticism101 (talk) 02:43, 30 December 2008 (UTC)

text: I rest my case. Your explanation was valid and reassuring.
--AwesomeOpossuminthelake (talk) 04:00, 30 December 2008 (UTC)
thread_title: Spitzenkorper

message: To a large extent this article comprises a set of introductions to some organelles where a membrane is an important constituent. The article includes little description of the system. How do these organelles function together? What is the reason that these organelles are considered an entity together that is worthy of its own Wikipedia article? Ribosomes function in close cooperation with ER when producing certain proteins. Why are the ribosomes not considered constituents of the system? Why are neither mitochondria, flagella nor cilia discussed? I am not suggesting that they should be, just that the article should make it obvious that they are not part of the system. Here and there, the article does describe cooperation between organelles. But it does not seem to focus on the system, although it purports to be about a system. --Ettrig (talk) 16:50, 8 February 2009 (UTC)
replies: text: That's a good point. Under the current definition I don't see why the mitochondria are omitted. Tim Vickers (talk) 17:23, 8 February 2009 (UTC)
replies: text:  I think the concept of endomembrane system is based on the fact that the structures mentioned in the entry are all derived via the exchange of a common phospholipid membrane. The ER membrane is a continuum of the nuclear membrane and with the vesicles which in turn fuse to form Golgi bodies and eventually lysosomes and plasma membrane. They are all interconnected via exchange of membranes.  The mitochondria is not derived from the endo-membrane phospho-lipids. The article is not about random cell organelles with membranes. Perhaps a better job of stating this information and what connects these structures - which would exclude cilia, flagella, and mitochondria - is needed? --JimmyButler (talk) 03:57, 9 February 2009 (UTC)

text: Here is the line from the article that perhaps needs to be elevated to a higher status in the intro: The organelles of the endomembrane system are related through direct contact or by the transfer of membrane segments as vesicles. --JimmyButler (talk) 04:08, 9 February 2009 (UTC)
replies: text: Compare with the article about the Supreme Court. The court comprises a number of judges. Indeed the article does contain a list of current judges and does give some facts about them. But this list does not constitute the bulk of the article. And it should not. As a contrast the endomembrane system article consists to about 90% of descriptions of the organelles in themselves. All these organelles have their own articles. So this article is not needed for descriptions of the organelles. The organelles in themselves are not the subject matter of this article. It is about a particular system, that these organelles take part in. But up to now it seems that nobody has even started to describe this system. The book "The world of the cell" by Kleinsmith, Becker, Hardin and Bertoni has a 60 page chapter about the Endomembrane system and peroxisomes. This chapter contains most of the books information about the constituent organelles. This is OK for a textbook, but not for an encyclopedia. Paragraphs concerning system aspects are Glycosylation, Protein trafficking, Exocytosis, Endocytosis, Transport within the cell. --Ettrig (talk) 20:53, 9 February 2009 (UTC)
replies: text: I missed the theme in the previous post. Agreed. Unless there is a focus on the relationship of these parts to each other (within the system); the article is merely an assemblage of pre-existing articles on cell organelles compiled on one page. The emphasis should shift now to the relationship that ties each organelle together- what makes it a system. Is there enough information to do this? If not; then the reason behind it being a stub becomes apparent.--JimmyButler (talk) 17:40, 10 February 2009 (UTC)

text: Yes, the concept of lipid flow is a central one. We need to outline the concept and initially define the system as a whole - membranes that are made from each other and exchange components freely. Next, in each section on a component organelle, we describe the organelle and summarise the evidence for this being considered part of the system. We could even have a section on plastids and summarise the evidence that they are NOT part of the system. Lots of material here for a long article, but rather a technical one. Tim Vickers (talk) 18:35, 10 February 2009 (UTC)

text: I agree with Tim Vickers' last post.  I seem to have left out some information on exactly why these organelles are considered a system.  In my defense though, one would need a decent description of what the organelles themselves do before comprehending how the organelles work as a system.--VivaLaLacy (talk) 23:35, 10 February 2009 (UTC)
thread_title: Where is the system?

message: The first proposal of the "endomembrane system" was in this book chapter
MORRE, D. J. & MOLLENHAUER, H. H. (1974). The endomembrane concept: a functional integration of endoplasmic reticulum and Golgi apparatus. In Dynamic Aspects of Plant infrastructure (ed. A. W. Robards), pp. 84-137. London, New York, etc.: McGraw-Hill.
This book section link gives a good overview of the concept. Tim Vickers (talk) 23:04, 9 February 2009 (UTC)
replies: text: This is the best reference I could find link, it is a review with one of the authors being Morré, one of the original proposers of the concept. If you need the Pdf e-mail me. Tim Vickers (talk) 23:07, 9 February 2009 (UTC)
replies: text: I think I'm going to incorporate an overview of what makes these organelles a system in to the lead using this link.  Then I/we, like Tim Vickers wrote above, could write something about why each particular organelle is included in the system under the section of the component being explained.  It may not really be necessary to devote a section to why some components are not included, its a little obvious.  The mitochondria is not included simply because it has nothing to do with the proteins and lipids that go through the endomembrane system, its main purpose is to generate ATP.  Maybe a couple sentences in the lead would suffice?  —Preceding unsigned comment added by VivaLaLacy (talk • contribs) 23:55, 10 February 2009 (UTC)
replies: text: I just now noticed the changes made in the lead section, so disregard the first sentence of the comment above. --VivaLaLacy (talk) 01:54, 11 February 2009 (UTC)
replies: text: OK, but feel free to improve that bit. I might have been a bit too technical? Tim Vickers (talk) 03:30, 11 February 2009 (UTC)
replies: text: Really good comments and additions by Tim. Thanks. This article will become even more beautiful. The conclusion about mitochondria above is probably right. But the argument is wrong. A large percentage of the proteins used in the mitochondria are coded in nuclear DNA, synthesized in ER and transported to the mitochondrion. See e.g. Protein targeting#Sorting of proteins to mitochondria, although it is a bit obscure. --Ettrig (talk) 09:19, 11 February 2009 (UTC)
replies: text: Synthesised in the cytosol, up to the point where the import signal is exposed, then synthesis stops, the ribosome then docks onto the mitochondrion, and protein synthesis resumes. The important point is that membrane vesicles are not involved in this process so lipids will not flow from the ER to the mitochondrion.  Tim Vickers (talk) 16:17, 11 February 2009 (UTC)
replies: text: Yes, I was wrong. --Ettrig (talk) 16:27, 11 February 2009 (UTC)

text: I'm working on mitochondrial proteins at the moment, so the topic is much on my mind! Tim Vickers (talk) 16:40, 11 February 2009 (UTC)
thread_title: History

message: This article may be beneficial,  Organization of the Endomembrane System.  Is there anyway to get free access to the pdf?
By the way, would you mind emailing me the pdf for this article.  If you  click here you should be able to email me.  --VivaLaLacy (talk) 22:30, 12 February 2009 (UTC)
thread_title: Links

message: The article specifically excludes peroxisomes from the endomembrane system, but the peroxisome article states that they are derived from the endoplasmic reticulum. For what reason/by what criterion are peroxisomes excluded from the endomembrane system if they are derived from a portion of it? --Khajidha (talk) 19:06, 31 May 2011 (UTC)
thread_title:  Peroxisomes 

message: Glycogen hydrolysis does not require "glucose phosphate" as the article states. Glycogen hydrolysis requires glycogen, phosphate, and the enzyme glycogen phosphorylase; glucose-1-phosphate is the product of that reaction. Glucose-1-phosphate is then turned into glucose-6-phosphate by the enzyme phosphoglucomutase. Glucose-6-phosphatase, present mostly in the liver, then can remove the phosphate from glucose-6-phosphate, forming glucose and phosphate.  — Preceding unsigned comment added by 97.90.155.218 (talk) 05:14, 10 August 2011 (UTC)
replies: text: I just came to the talk page to note this, not good that this error has remained for almost a whole year. See glycogenolysis  — Preceding unsigned comment added by Zynwyx (talk • contribs) 11:02, 25 May 2012 (UTC)
thread_title:  Glycogen 

message: Substituted at 14:29, 29 April 2016 (UTC)
thread_title: Assessment comment

message: Frog 2409:4073:313:641:2CDF:4B55:142:DBB5 (talk) 15:01, 20 December 2021 (UTC)
thread_title:  Zoology