Talk:Alkaline phosphatase

message: I've included some information on the research portion which says that mutant AK are usually used for research as their enzyme activity are higher.Nbazyan (talk)
I'm going to include some introducing information for human physiology. I will include which isozymes in human serum predominate, and a fact of AK involving childhood.Nbazyan (talk) Furthermore, I'm going to edit the part on elevated alkaline phosphatase to include where exactly the alkaline phosphatase are coming from (referring to both skeletal and serum alkaline phosphatase) If anyone has any papers talking about the mechanisms, or which have more clarity on this, feel free to throw the name of the papers to me.Nbazyan (talk)  —Preceding undated comment added 07:25, 1 May 2016 (UTC)
replies: text: Seconded. I just added something from the Oxford Textbook about heat stability, but I reckon there are now more sensitive ELISA or nephelometry-based modalities available. JFW | T@lk 19:50, 12 September 2005 (UTC)
thread_title: note

message: The change form 14:07, 9 December 2005 says - "Removing these phosphates prevents the DNA from ligating (the 5' end attaching to the 3' end of another molecule), thereby preventing DNA degradation until the next step of the process for which it is being prepared". Isn't an intramolecular ligation posible too? I think so, well, depending on how long these molecules are, right? If that's correct then we should revert this part to the original. Plz post a comment. Boris 13:57, 15 December 2005 (UTC)
thread_title: Use in research

message: It would be helpful if the article could indicate what level would be considered significantly elevated.
Also, does anyone have any paediatric values by either age or developmental stage - there is this idea that they are higher than adult values, but then how do we differentiate between raised Alk Phos from growth, and that from other pathologies such as low vitamin D (especially when we can't get the doctors to do Vitamin D tests)Kiwihelen (talk) 07:29, 15 August 2009 (UTC)
replies: text: I came here to ask for the same thing .. normal levels please Dr B2 (talk) 14:09, 24 August 2011 (UTC)
thread_title:  Human: Diagnostic Use 

message: My Alkaline phosphatase is extremely high. Who could tell me why that is, and how our body recieves Alkaline phosphatase (i.e. what kind of food contains Alkaline phosphatase). How could I make it lower..Please help
:ALP is a generally considered a marker of high bone activity - it is secreted by osteoblasts (bone forming cells). High ALP is often high in a high bone turnover state - i.e. when bone resorption is also high. This can be confirmed by other biochemical markers of bone resorption.
:ALP is high in conditions such as Paget's disease of bone - a high bone turnover state that can lead to weakened and deformed bones, as well as bone pain.
:These conditions are treated with drugs, such as bisphosphonates rather than diet. I suggest you consult your GP if you are concerned. Dr Aaron 04:40, 1 August 2006 (UTC)
thread_title:  Levels of Alkaline Phosphatase 

message: None of the stuff on this page has citations, and none of the stuff is mentioned in the references or external links at the bottom of the page. Article needs to be flagged for this.  —Preceding unsigned comment added by Farcanell (talk • contribs) 07:13, 11 October 2008 (UTC)
thread_title:  Needs citation big time 

message: This article needs a discussion of bone specific alkaline phosphatase (BSAP) which plays a role in, and is used as a marker of, bone formation.Struvite (talk) 00:45, 23 March 2012 (UTC)
thread_title:  BSAP 

message: The article is overall neutral. The article is mostly presenting information about the alkaline phosphatase enzyme and its relevance to research and science. There does not seem to be any claims that appear heavily biased towards a particular position. There also does not seem to be any viewpoints that are over represented or under represented in the article which seems to fit with the article topic since this is a science article detailing the information about the alkaline phosphatase enzyme Belunny23 (talk) 01:19, 2 April 2023 (UTC)
thread_title:  Evaluating Tone of Article  

message: — Assignment last updated by Mariamismail34 (talk) 15:27, 2 May 2024 (UTC)
thread_title: Wiki Education assignment: CHEM 378