lflage/wiki-talks huggingface dataset:
Talk:Tioguanine

message: I think this piece is a scandal. Someone who is not very informed about 6-TG has written this. The article about 6-mercaptopurine (which is intracellularly converted to 6-TG) is much better.
I dont have time to correct all this, sorry. I work in a cancer research lab, where I analyze the amount of deoxy-6-Thioguanine in patient DNA (yes, the patients get 6MP - not 6TG)  —Preceding unsigned comment added by 130.226.107.2 (talk) 13:34, 28 October 2009 (UTC)
replies: text: Agreed...I was thinking about translating this into Chinese, but found its quality is too poor. The same goes for Melphalan, Dacarbazine, Procarbazine, Cyclosporin. The German versions are much better.--Jsjsjs1111 (talk) 12:40, 21 June 2012 (UTC)
thread_title:  Very inaccurate 

message: I am undertaking a major revision of this article - the above criticisms are very true. As the German version is far better, I am basing my revision on this, but with updates. This drug is undergoing a resurgence of interest - latest references will be included. Introductory part finished so far (24 Aug, 1715 Aust EST), more to follow. I have published widely on the topic of thiopurines and more specifically thioguanine in recent times, and am happy to supply details if required.  — Preceding unsigned comment added by Johnaduley (talk • contribs) 07:15, 24 August 2012 (UTC)
thread_title: Major edit

message: Does anyone know the reasoning behind the INN name change? Current literature still seems to be using Thioguanine, while Tioguanine seems to be widely used by manufacturers. I'm baffled why it would need to change from Thioguanine. Is it possible to find a reference for the INN change?  — Preceding unsigned comment added by 67.171.167.38 (talk) 23:12, 24 May 2013 (UTC)
thread_title:  Why was the name changed?
Talk:Carbenoxolone

message: I believe the IUPAC Name is:
(3beta)-3-[(3-carboxypropanoyl)oxy]-11-oxoolean-12-en-30-oic acid--ChemSpiderMan (talk) 23:50, 18 May 2008 (UTC)
replies: text: Added. Fvasconcellos (t·c) 19:12, 25 May 2008 (UTC)
thread_title:  IUPAC name
Talk:National Airlines (1934–1980)

message: Your fourth paragraph states;  On November 10, 1958, National became the first airline to introduce domestic jet service in the United States, with a flight between Miami's international airport and Idlewild International Airport in New York City.
Actually this took place on December 10th (not November) and the first flight originated at Idlewild, bound for Miami, using a Boeing 707 leased from PanAm.  For additional details you can refer to;  National, Airline Of The Stars, An Illustrated History by George W. Cearley, Jr.  —Preceding unsigned comment added by 66.32.118.149 (talk) 16:24, 3 August 2008 (UTC)
thread_title:  Opening comment 

message: Shouldn't there be a mention of the famous 1960's commercial that had the tag line, "Is this anyway to run an airline? You bet it is!" spoken by Andrea Dromm? __209.179.55.119 (talk) 02:40, 27 October 2015 (UTC)
thread_title:  The famous 60's commercial 
Talk:Hermann Heller (legal scholar)

message: This name is mentioned but its owner is unidentified. Mctougis (talk) 22:26, 28 July 2023 (UTC)
thread_title:  Who is "Bernstein"? 

message: It's false that Smid was the main drafter of the Weimar Constitution. The person who did that was Preuss. Mctougis (talk) 22:27, 28 July 2023 (UTC)
thread_title:  Smid 

message: And what degree did he receive?How was he employed? I get that this article is a "stub"-- but it's a very poor start indeed. Mctougis (talk) 22:31, 28 July 2023 (UTC)
replies: text: Heller studied "Rechts- und Staatswissenschaften" (i.e. law, specialising in public law) at the universities of Vienna, Innsbruck, Graz und Kiel, was promoviert (doctorate - subject not given) in 1915 at Graz and habilitated in Rechtsphilosophie, Staatslehre und Staatsrecht in 1920 at Kiel with a thesis Hegel und der national Machtstaatsgedanke in  Deutschland (Hegel and the Idea of the National Power State in Germany):  Errantios (talk) 03:15, 29 July 2023 (UTC)
thread_title:  Where did he study?
Talk:Darunavir

message: Dylan, Lindsey and I are part of the WikiProject Pharmacology course. We have decided to edit the lead and Side Effects sections to improve information and syntax. Specifically over the next couple of weeks, we would like to make the lead have more neutral wording, and reword the Side Effects section to be more accessible to a general audience. Please let us know if there are any problems with this plan. Thank you. Ktakamura (talk) 18:33, 3 November 2016 (UTC)
thread_title:  UCSF WikiProject Pharmacology 

message: Question 1 (Shannan): Does the draft submission reflect a neutral point of view? If not, specify…
A: Focusing on the sections that your group edited (lead and side effects), I thought that your writing definitely reflected a neutral point of view. When reading, I felt that the author was trustworthy, and I also liked that there were no obvious statements trying to make darunavir sound superior to the many other HIV medications available. The information was well balanced and supported through sources. One thing that I did notice, although this doesn't fit the question I am answering, was that you may want to consider moving the drug interaction information to a different section instead of the side effects section. Great job! ST14 (talk) 19:08, 14 November 2016 (UTC)
thread_title:  Peer Review: Done by Group 8
Talk:Rasagiline

message: Corrected introduction to be in accordance with ref. 1, which says that trials to determine whether rasagiline is MAO-B selective have NOT YET been conducted. 208.102.122.87 (talk) 02:27, 22 January 2008 (UTC)
thread_title: comment1

message: Aziltec (Rasagiline) is an MAO inhibitor.  Pharmacists in the USA who see this drug being prescribed will immediately check for contraindications of MAO inhibitors with other drugs and that is a very long list.  Aziltec is one of the few remaining MAO inhibitors still in use.  The "Safety" section of this article should be expanded.  Heaven forbid someone take Aziltec with a serotonin reuptake inhibitor like Paxil or Klonopin. Frank Layden (talk) 00:21, 12 December 2013 (UTC)
replies: text: Yes it did suck.  I just worked it over. Jytdog (talk) 05:48, 7 February 2016 (UTC)
thread_title:  This article is biased and appears to be written by the manufacturer 

message: The study provided showing that this is an MAO-B was written by the manufacturer.
"and appears to be especially useful in dealing with non-motor symptoms like fatigue" that doesn't seem right
"Side effects when the drug is taken alone include flu-like symptoms, joint pain, depression, stomach upset, headache, dizziness, and insomnia" this sounds a lot like the effects of serotonin
Also look at the molecular structure it's literally shaped like a serotonin molecule
Whereas selegiline which definitely is a dopaminergic drug is shaped like a dopamine molecule.
Something doesn't seem quite right with this medication. JoeC46 (talk) 13:03, 11 May 2023 (UTC)
thread_title:  Is this really an MAO-B?
Talk:Hermann Iseke

message: I have my doubts that he was a doctor/physician. This is not mentioned at all in the German Wikipedia and there is nothing referring to it in the Biography. Possible this was a mistake due to his „Dr.“. It is in the text since the first version.
2003:E7:1F0E:4200:38BF:3AF:13A8:37E5 (talk) 19:03, 8 November 2019 (UTC)
thread_title:  Was he a doctor?
Talk:Hermann Jacobi

message: In 1889, Jacobi became professor in Bonn, not in Cologne. By the way, there was no university in Cologne at that time.  —Preceding unsigned comment added by 93.232.254.83 (talk) 09:43, 23 May 2010 (UTC)
replies: text: Thank you for your suggestion. When you believe an article needs improvement, please feel free to make those changes.  Wikipedia is a wiki, so anyone can edit almost any article by simply following the  link at the top. The Wikipedia community encourages you to be bold in updating pages. Don't worry too much about making honest mistakes—they're likely to be found and corrected quickly. If you're not sure how editing works, check out how to edit a page, or use the sandbox to try out your editing skills.  New contributors are always welcome. You don't even need to log in (although there are many reasons why you might want to). Shreevatsa (talk) 17:17, 23 May 2010 (UTC)
replies: text: I subscribe to these suggestions with the addition that the editor should have verifiable references at hand to support the changes they make and note the references when they make the changes. I changed the "noreferences" banner for this article to "refimprove".  I think some of the mysterious information is a translation of German Wikipedia. I wish mistakes got corrected quickly, and often they do, but for a less-visited article like this they may hang around for awhile. I saw one project above rating this article at B, but I think start is more realistic, although a good case might be made for C. Bob Burkhardt (talk) 17:18, 28 January 2011 (UTC)
thread_title:  Wrong information
Talk:Lomustine

message: Our Cat, 13 yrs, 7,5kg, has a tumor in the backbone, preciseley bone marrow. Obviously Lomustine is also used for animals with tumors having direct impact on neurological diseases.  —Preceding unsigned comment added by 92.106.156.196 (talk) 17:39, 23 February 2011 (UTC)

message: It would be useful to have an international perspective on the price of this drug in other countries. --Nbauman (talk) 18:06, 14 January 2018 (UTC)
thread_title:  International perspective? 

message: This implies that abnormal clinical test parameters cause liver toxicity.  I believe that the truth is the reverse: Liver toxicity causes abnormal test parameters.  Indeed, when I look at the source cited at https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/017588s042lbl.pdf , it reads, 
In other words, the clinical test parameters are manifestations (not causes) of liver toxicity.
I propose to adjust the wording of the article text to read as follows:
"Hepatotoxicity is signaled by increased levels of liver transaminases, alkaline phosphatase, and bilirubin with lomustine use. Liver enzymes and function should be monitored during use and dose should be adjusted based on toxicity levels."
This is supported by the source and better reflects the causality implied by the source.
Boatman4 (talk) 18:31, 25 September 2023 (UTC)
thread_title:  Proposed fix for inverted causality in hepatotoxicity paragraph
Talk:Nina Fedoroff

message: “Oh great, our State Department is pushing G.M. food. She’s the Ambassador from Monsanto.” What’s your response?
Nina Fedoroff: How do I answer him? My answer is: There’s almost no food that isn’t genetically modified. Genetic modification is the basis of all evolution.
* http://www.nytimes.com/2008/08/19/science/19conv.html?_r=1&oref=slogin —Preceding unsigned comment added by 217.232.125.154 (talk) 16:11, 20 January 2009 (UTC)
thread_title: She’s the Ambassador from Monsanto

message: Fedoroff is considered a 'population alarmist' by some groups. She has been quoted as saying “humans had exceeded the Earth's ‘limits of sustainability’." A quote from a recent PRI (Population Research Institute)article follows:
"What about the 6.8 billion the world already supports? the BBC asked her. “There are probably already too many people on the planet," Fedoroff replied." —Preceding unsigned comment added by 67.139.40.170 (talk) 18:38, 8 April 2009 (UTC)
thread_title:  Controversy 

message: Updated links    148.177.1.211 (talk) 13:23, 14 January 2015 (UTC)
thread_title:  External Links 

message: I have commenced a tidy-up of the Bibliography section using cite templates. Capitalization and punctuation follow standard cataloguing rules in AACR2 and RDA, as much as Wikipedia templates allow it. ISBNs and other persistent identifiers, where available, are commented out, but still available for reference. Feel free to continue. Sunwin1960 (talk) 06:21, 20 December 2016 (UTC)
thread_title:  Bibliography
Talk:Hermes Pan

message: Before editing in or out any information from this article, you could do a lot worse that sending me a note. Thanks Politis 15:11, 14 November 2007 (UTC)
replies: text: Er, no, that's not how it works.  We do not filter our edits to this or any other article through individual editors.  If you do not like an edit, it is your prerogative to do something about it.  --  Jack of Oz  ... speak! ...  11:01, 16 August 2010 (UTC)
thread_title: Ask

message: "His father was from Aigio in Peloponnese where his family had opened the first theatre." What sort of theater? Be specific. WilliamSommerwerck (talk) 15:26, 27 March 2012 (UTC)
thread_title: there were Greek theaters 2500 years ago...
Talk:Herminie Templeton Kavanagh

message: In the box, says Irish.
Wasn't this lady in fact. Irish by heritage;  English by birth; American by marriage ( or through naturalisation ?  It doesn't mention ). ?
So English-Irish-American.   Claverhouse (talk) 23:43, 6 August 2022 (UTC)
thread_title:  Nationality
Talk:Lambeth degree

message: Will the Lambeth doctorate in philosophy be called PhD or DPhil? All the other doctorates (DD, DCL, DM, DLitt, DMus - no mention of DSc) are Oxford abbreviations, and indeed the degree of DCL is an Oxford degree - Cambridge confers the LLD. It would make sense for the abbreviation to be DPhil.--Oxonian2006 (talk) 00:55, 19 February 2008 (UTC)
thread_title: PhD

message: I think not. As it happens, I have the Lambeth Diploma; and on the rare occasions when I've used postnominals I've always described as "STh(Lambeth)", not "STh(Cantuar)"Kranf (talk) 19:01, 10 January 2009 (UTC)
thread_title:  "Cantuar"?
Talk:Hesketh Pearson

message: After the war, Pearson returned to the stage and, in 1921, met Hugh Kingsmill, an encounter which, thanks to Kingsmill's charismatic friendship and influence, changed his life.
:Changed his life how? This needs explanation. Valetude (talk) 10:45, 6 June 2019 (UTC)
thread_title:  Unexplained
Talk:Alexander Hamilton Church

message: Some suggestions for improvement as the article is expanded:
*Appropriate infobox should be added 
*Photograph should be added from a source with a free license, if available
*Basic biographical information required
*Article needs expanding and should emphasise reasons for notability of subject
*Expanded article should be divided into appropriate subheadings
*Information on research should be expanded and references required
*References should be added, preferably in the inline format  
*External links to useful online resources should be added if available
Espresso Addict 23:12, 18 July 2007 (UTC)
thread_title: Review comments
Talk:Hilda Runciman, Viscountess Runciman of Doxford

message: I have deleted two copyrighted images that had been imported in from Commons by the user who uploaded them from the NPG. I had posted a message to the users talkpage advising them that the images were copyrighted. The user has visited their talkpage but has not responded to my message. Hopefully the user will remove these images from Commons. They have been advised of the option to upload one image to wikipedia which could be used in this article under fair use. Graemp (talk) 13:28, 19 September 2014 (UTC)
thread_title: National Portrait Gallery images

message: In Liberal Party politics she was a strong advocate of H H Asquith
But her husband's wiki page says:
(The Board of Trade in October 1914) also discussed Asquith's removal, since his wife, Hilda Runciman, had called the Prime Minister "brains in aspic". Valetude (talk) 10:21, 8 March 2020 (UTC)
thread_title:  Views on Asquith
Talk:Hildegard Peplau

message: ,great work on your edits. You have substantially expanded the article. Clearly, you've done your research and learned about Peplau's theory, nursing, and the nurse-patient relationship. I'm glad you were able to share that learning with Wikipedia readers. You have thorough reviews. They're long reviews but I think you'll see there are common themes and suggestions for achievable edits to further enhance the article. Some of the editing comments don't pertain to the section you edited but you should feel free to act on any of them. My only additional minor advice is to do a read through for consistent spelling (e.g., counselor/councilor). Well done. LynnMcCleary (talk) 03:39, 17 November 2014 (UTC)
thread_title:  Professor comments on student edits 

message: The following notes were added by an unauthenticated user (IP address) to the bottom of the article. I move them here in case they are useful for further research and citation. Dorevabelfiore (talk) 17:16, 8 April 2023 (UTC)
thread_title: Notes from unauthenticated user
Talk:Hillary Brooke

message: Was this Arthur Peterson in fact her brother?  The New York Times obituary cited here says her brother of that name survived her.  She died in 1999.  The article on the actor Arthur Peterson, born November 18, 1912, says he was born and raised in Mandan North Dakota.  Hillary Brooke, born September 8, 1914, was from Astoria Queens.  I strongly suspect that they are different people.  Anyone know?  Kostaki mou (talk) 06:39, 20 July 2020 (UTC)
thread_title:  "Her brother, actor Arthur Peterson, died in 1996"
Talk:The Work Foundation

message: In 2014 Professor Geraint Johnes became Director of The Work Foundation http://www.theworkfoundation.com/Aboutus/Our-People/293/Professor-Geraint-Johnes Nikola EA (talk) 16:39, 17 March 2014 (UTC)
thread_title: Out of date information

message: The link in the info box just needs to lose the extension index.aspx and just be updated to www.theworkfoundation.com Angelo leango (talk) 09:50, 15 April 2013 (UTC)
thread_title: Out of date link

message: "In 2008 Stephen Bevan replaced Hutton as managing director" needs to be updated. There is a new structure. So it is now just the title of 'director' who now is Ian Brinkley. http://www.theworkfoundation.com/Aboutus/Our-People/9/Ian-Brinkley Angelo leango (talk) 12:13, 9 April 2013 (UTC)
thread_title: Needs some updates to content 

message: We need more info on the history of the organization. Custodiet ipsos custodes talk 19:22, 18 July 2007 (UTC)
thread_title: Need more info on history

message: Please don't copy text from other web sites without permission.  Minor changes to text does not avoid copyright infringement.   Custodiet ipsos custodes's recent contribution is still an obvious copy of : for example, the sentence that begins "The Boys' Welfare Association widened its focus".  Please contribute only material you wrote yourself or that has been explicitly contributed by its author.  Thanks!  Crimethinker 00:50, 9 August 2007 (UTC)
replies: text: I have radically rewritten the history and used multiple sources. There is no copyright infringement now. Custodiet ipsos custodes talk 16:32, 9 August 2007 (UTC)
thread_title: Copyright violations

message: I have reverted some recent edits that appear fron the editor's username and the content removed or revised could be a potential conflict of interest. Will advise editor to come here to discuss. Tmol42 (talk) 14:28, 9 May 2015 (UTC)
thread_title:  Potential COI edits
Talk:Defibrotide

message: On pubmed I found only 1 study http://www.ncbi.nlm.nih.gov/pubmed/1428206
There is also a study (but without abstract on line) about its use on Iga nephropathy (kidney disease) http://www.ncbi.nlm.nih.gov/pubmed/8700366
Both of the above studies are old. 688dim (talk) 19:17, 4 January 2015 (UTC)
thread_title: Lack of evidence for use on renal (kidney) dialysis

message: It says "is a deoxyribonucleic acid derivative (single-stranded)"  but how long is it, what base sequence, and how was it modified ? - Rod57 (talk) 17:00, 10 April 2016 (UTC)
thread_title:  What is it precisely 

message: Mode of action does not explain how it increases "levels of prostaglandin I2, E2, and prostacyclin," - Rod57 (talk) 17:02, 10 April 2016 (UTC)
thread_title:  How does it work 

message: Should say what countries, what indications and since when - or confirm that it has been used (where) off-label. - Rod57 (talk) 17:09, 10 April 2016 (UTC)
thread_title:  Where was it used before FDA approval 
Talk:Hiram Gill

message: If anyone does an article on "Wappy" Wappenstein, here is a photo. - Jmabel | Talk 01:50, 19 May 2010 (UTC)
thread_title: Wappenstein

message: I'm not sure how long, or when, Austin Griffiths was his police chief (though I'm sure David Wilma would not have erred entirely). The "End of the Silly Season" article cited as a source is a contemporary 1916 account and refers to a police chief Beckingham involved in the saloon raids. - Jmabel | Talk 21:08, 27 February 2023 (UTC)
thread_title:  Austin Griffiths
Talk:Hiram Percy Maxim

message: He was american Capitalist and Exploiter. His father was mass murderer who made huge money on mashine gun which killed many people during 1 WW ...   — Preceding unsigned comment added by 205.201.55.24 (talk) 09:21, 6 July 2020 (UTC)

message: I believe it was Sir Hiram Maxim, HPM's father, who was the aviation pioneer.  —Preceding unsigned comment added by FLAHAM (talk • contribs) 20:19, 25 February 2009 (UTC)
thread_title: Untitled

message: After reading up on the {Infobox person} params for another article, I happened to notice the Callsign parameter (having enjoyed the ham radio hobby in high school & college). So, while adding the W1AW callsign to the page's infobox, I scanned through the article and saw that the Marriage section had several unrelated (no pun intended) paragraphs after the first one.  Hiram's Accomplishments seemed the obvious choice for a new section Header to split the successive paragraphs into.  And the original paragraph's topic seemed more-suited to be titled Marriage & Family.
best regards(73)— DennisDallas (talk) 11:46, 15 October 2010 (UTC)
thread_title:  Sections re-organized: <br> ''Marriage'' &mdash;>''Marriage & Family'' &emsp;+&emsp; ''Accomplishments'' 

message: Not sure if it is a "Tesla" type thing but they say they were established in 1895.  Although that would not gibe with Maxim's work history, they make industrial noise suppression installations like ducting, so it seems like it might be related to him vs. a car muffler or weapon suppressor company trying to capitalize on name recognition.108.28.226.250 (talk) 03:20, 6 October 2023 (UTC)
thread_title:  Texas company called "Maxim Silencers"
Talk:Man, Economy, and State

message: This might sound like an immature comment, but here it goes. For being such a seminal work, that introduction sucks. If I ever get a chance, I'll see if I can improve it. If not, this would be something to consider adding to as a note to anybody who's interested. Lighthead þ 00:03, 4 November 2016 (UTC)
thread_title:  No info as to the importance of the work? 

message: It is not original research to write a summary that merely describes a book's contents in shorter length, without attempting a literary analysis or anything like that. I believe WP:USEPRIMARY is on my side when it gives the example of a novel. It would be hard for an encyclopedia to cover books if they could not be described like I did, and there is no indication in the rules about original research that forbidding this was anything like the intent. Thiagovscoelho (talk) 00:50, 25 February 2023 (UTC)
replies: text: Did an AI write the summary? Llll5032 (talk) 23:13, 18 December 2023 (UTC)
thread_title:  Not original research 

message: I think Power and Market should be merged here, since most references to it have been to the edition that publishes it together with Man, Economy and State, and as such, it is hard to find sources specifically about P&M rather than to both books as a unit. Thiagovscoelho (talk) 16:06, 30 May 2023 (UTC)
replies: text: Klbrain (talk) 21:16, 18 December 2023 (UTC)
thread_title:  Merger proposal
Talk:Vincamine

message: The actual absolute configuration of centers in natural vincamine implies that stereocenters 20 and 21 in the depicted formula be inverted.(literature and personal work)
The depicted formula actually corresponds to the enantiomer of 16-epi vincamine...
93.12.207.139 (talk) 07:20, 6 November 2009 (UTC)
thread_title:  erroneous molecular formula of vincamine