Talk:Index case

message: I like the "list of miscellaneous information" -- the list of "Patient Zeros in Fiction." I think it should get to stay! --Amanda French (talk) 14:12, 12 August 2008 (UTC)
thread_title: Untitled

message: We are certain that our primary case, a one Richard Brown, contracted the disease in a regional park, but we don't know which. Here is our patient zero, if you take a look at my report, I indicated that there were traces of... (please correct me if I am wrong, and your welcomed for the House-ish theme to my response. AV) —Preceding unsigned comment added by 70.82.139.21 (talk) 21:48, 6 November 2009
::This begs the question, who are you? and what is your report? And who is Richard Brown?Riverpa (talk) 19:54, 19 November 2009 (UTC)
thread_title:  Richard Brown 

message: I have de-emphasized the use of the term Patient Zero from this article for a couple of reasons. One, it has significant differences from the meaning of the term Index patient. Index patient is the first identified case, other cases are then tracked forward and backward from it. Patient Zero appears to used more as the genesis of a disease. Two, Index patient is an epidemiological term, Patient Zero is not. Three, the meaning of Patient Zero seems to have been established in reference to the HIV epidemic, and it has drifted from there to be used in other ways in the popular press. Therefore the meaning seems to be 1) rather recent and 2)in flux. 
If someone feels that it is important enough, I would prefer to see a new article for the term Patient Zero, rather than conflating it with Index patient, which has a stable and well defined meaning already. Of course, there is significant overlap in the meanings which is why I left it in the article, just not on an equal basis as a definition or synonym of Index patient.Riverpa (talk) 19:52, 19 November 2009 (UTC)
replies: text: Welcome to  Wikipedia. You have a good point and a new article may be useful. A useful resource for writing about medical topics is WP:RSMED. Billhpike (talk) 07:26, 18 November 2017 (UTC)

text: On second thought, while index case and primary case refer to different things in most cases, patient zero widely used to refer to both, and in such cases the term index case is given a broader definition than is technically intended as per http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)62331-X/fulltext. While the primary case may or may not be known, index case also generally used to refer to earliest known case in subsequent literature or the first documented case, even after the fact. i.e. Mabalo Lokela, who died of a then-unknown illness but to whom the resulting outbreak of what came to be named Ebola was later traced back to. Technically, in epidemiological terms as per the article above, the index case or cases would refer to those first individuals who were reported at the onset of what was eventually suspected to be an outbreak of Ebola. However, in general terms, Lokela may be referred to as patient zero or an index case as even though Ebola was not suspected or reported at the time of Lokela's death, the outbreak was eventually traced back to him and his case of Ebola was reported after the fact. --Meriid (talk) 21:05, 18 November 2017 (UTC)
thread_title: Patient Zero

message: Is there any practical medical use in the determination of the exact index case or is it a mere point of fact that comes out of an exhaustive epidemiological investigation? I don't get its medical significance from the entry. I'm guessing that maybe when the index case is resistant and keeps causing new outbreaks .. but chances he/she didn't create a new vessel in an epidemic are rather slim. Maybe the index case can yield clues on how the new critter was allowed to evolve or something? The entry is missing something.
Dugodugo (talk) 03:03, 13 December 2011 (UTC)
replies: text: The index patient is the first human case known. The first time the disease is expressed in a human that anyone can figure in light of a new and unknown disease. Doctors always share information about unusual symptoms they can't categorize. This is how the real index cases were tracked down in HIV. By using the "Letters to the Editor" of the New England Journal of Medicine that came in in the 1970s. Several doctors described symptoms that did not fit any other known infectious disease process. These doctors had ordered blood and other tissue laboratory tests while they were caring for the patients. Epidemiologists were later able to go back and check these samples thanks to the doctors who'd written in to the NEJM. That doesn't mean that at some time in the distant past, other cases didn't happen. They just weren't made known. Everything, every disease process has a tipping point. In effect, an index patient represents the tipping point when a 'new' disease becomes known. Malke 2010 (talk) 01:57, 16 March 2013 (UTC)
replies: text: And yes, the index patient can reveal how the critter evolved. It's the transmission history. Most common source is mammal to mammal then to man, who is also a mammal. Like bat to pig then to humans. Knowing the transmission history means you can figure it out. Important to know for vaccine production. Malke 2010 (talk) 03:22, 16 March 2013 (UTC)

text: It's an epidemiological concept/term and is clearly an important factor in those studies. So yes, medically significant but in a different way than you were thinking, as pointed out above. Gotitbro (talk) 17:38, 1 October 2020 (UTC)
thread_title:  Importance 

message: Hello fellow Wikipedians,
I have just added archive links to  on Index case. Please take a moment to review my edit. If necessary, add  after the link to keep me from modifying it. Alternatively, you can add  to keep me off the page altogether. I made the following changes:
*Added archive https://web.archive.org/20051214123317/http://andrejkoymasky.com:80/liv/fam/biod3/duga1.html to http://andrejkoymasky.com/liv/fam/biod3/duga1.html
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thread_title:  External links modified 

message: Why is Gaëtan Dugas used as an example of an Index Case when epidemiology studies have proven this a not true and in the Wikipedia entry for Gaëtan Dugas it explicitly states he was not Patient Zero in the USA as earlier disease was found? Dugas gave many details of his partners and, as he was from Canada, he was designated Patient O, O standing for 'Out of area'.
It is dangerous to use a popular misconception as an example of the source of an epidemic. Andrew ranfurly (talk) 21:37, 15 December 2021 (UTC)
thread_title:  Gaëtan Dugas 

message: :The following is a closed discussion of a requested move. Please do not modify it. Subsequent comments should be made in a new section on the talk page. Editors desiring to contest the closing decision should consider a move review after discussing it on the closer's talk page. No further edits should be made to this discussion. 
The result of the move request was: not moved. (closed by non-admin page mover) Sceptre (talk) 19:27, 9 December 2022 (UTC)
replies: text: Index case →  – Patient zero is the WP:COMMONNAME of this subject. PhotographyEdits (talk) 10:44, 2 December 2022 (UTC)
thread_title:  Requested move 2 December 2022