Talk:Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

message: Here is a first draft. I tried to make an article that would complement the information that is already present in the Francis Crick and DNA articles. --JWSchmidt 23:52, 11 September 2005 (UTC)
thread_title: Untitled

message: :I found figure three to be extremely helpful. I was in an "Introduction to Biology" course at University of Arizona and diagrams like this helped me "wrap my mind around the idea" as my professor used to say. If you should think about adding any more diagrams like this, please do, as they are extremely useful to us MCB students.24.251.84.221 19:45, 18 October 2007 (UTC)
thread_title: Figure 3 enourmously helpful

message: This is a professional piece of work, but the article sounds a bit like an essay. Since this is an encyclopedia entry, it kind of uses a slightly patronising tone. Could this be fixed? Elle vécut heureuse à jamais (Be eudaimonic!) 23:53, 25 January 2006 (UTC)
replies: text: I have an unavoidable point of view with respect to this article (the original article in Nature). This was among the first primary biology articles I ever read and I have a deep admiration for the authors that was established at an early age and has lasted for decades. I think that the Science pearls project is a good idea for Wikipedia, and I have been thinking about the need to cite the secondary literature that has grown up around the original Nature article by Watson and Crick. I think most of the points I made in this "essay" are supported in sources that I cited in other Wikipedia articles that are hypertext linked to this one. I was reluctant to clutter this article with a bunch of citations. I think it is dangerous for one person's perspective to dominate the description of the significance of the Nature article; for example the "patronising tone" is entirely invisible to me. The only remedy is for other people to jump in and re-write. It is usually through the process of different POVs being expressed that the need for citations to sources is driven home and Wikipedia articles become more formal and NPOV. --JWSchmidt 01:02, 26 January 2006 (UTC)
thread_title:  sounds like an essay 

message: According to a section in the Nature (journal) article, Watson and Crick's work was not sent out for peer review before publication, on the grounds that John Maddox felt that "the paper could not have been refereed: its correctness is self-evident. No referee working in the field ... could have kept his mouth shut once he saw the structure..." 86.132.140.63 01:38, 6 April 2007 (UTC)
thread_title:  Lack of peer review (of the Nature article, not ours!) 

message: Admirable efforts, but a bit too wordy. We need to reduce the prose a bit and condense. Gautam  20:35, 25 April 2007 (UTC)
replies: text: Go for it! Super Aardvark 19:17, 26 April 2007 (UTC)
thread_title:  Needs Work 

message: The image :Image:FirstSketchOfDNADoubleHelix.jpg is used in this article under a claim of fair use, but it does not have an adequate explanation for why it meets the requirements for such images when used here.  In particular, for each page the image is used on, it must have an explanation linking to that page which explains why it needs to be used on that page.  Please check
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thread_title: Image copyright problem with Image:FirstSketchOfDNADoubleHelix.jpg

message: See Keto-enol_tautomerism#DNA. What is missing from the discussion here of model building and the discovery of the structure is the key insight that Watson received from a Pauling collaborator, and which he described clearly in The Double Helix. The original models that Watson and Crick had built had used the then-current textbook tautomeric form of the bases, which did not pair. The whole structure solution came together, almost immediately, when Watson had new model components made in the other tautomeric form (as shown in all textbooks now). This change was made based on advice from Jerry Donohue, a post doc in his lab, who had recently come to Cambridge from Paulings lab, and who knew that the textbooks were likely wrong. This help was, truly, a key part of the solution. A third key component of the solution was Chargraff's rule, that showed Watson to pair A with T and G with C. I believe Chargraff felt he should have received more credit for the help he gave. --AJim (talk) 01:01, 25 April 2009 (UTC)
thread_title:  tautomers 

message: The caption of Figure 2 notes that "this figure does not depict B-DNA."  In that case, what conformation does it depicted?  The helix doesn't look like A-DNA or Z-DNA.  To me, it looks like B-DNA without major or minor grooves.  The diagram in Watson and Crick's 1953 paper included DNA's major and minor grooves; our diagram should at least be on par with the accuracy theirs.  (I've tried to make this image myself in Inkscape, but haven't been able to produce anything worthwhile.) Emw (talk) 14:13, 25 April 2010 (UTC)
replies: text: It is simply a cartoon drawing of DNA in general. I don't think it is necessary for the caption to note that "this figure does not depict B-DNA". --Thorwald (talk) 00:09, 26 April 2010 (UTC)
thread_title:  Figure 2 

message: This article appears to cover a great deal of material also covered at History of molecular biology.  Why do we have two articles? WikiDan61ChatMe!ReadMe!! 14:18, 24 September 2012 (UTC)
thread_title:  Content forking 

message: I have read elsewhere that Rosalind Franklin's crystallography images were substantially more clear than those that Watson and Crick had previously seen, and that this clarity made a substantial difference to their ability to understand the layout of the DNA helix.  It's been several years since I read this so I don't recall the source, but I think the page would benefit by consideration of this point.  As a more literal level, the part of the page discussing how Franklin's work was shared with Crick could use some paragraph breaks. 
— Preceding unsigned comment added by 160.83.42.135 (talk) 08:58, 25 April 2013 (UTC)
thread_title:  Rosalind Franklin and image quality 

message: I removed this phrase, "along with Canadian Genetic Biologist David Collins and German Physicists Colin Cerimagic" from the first sentence. There are three papers on DNA, published on sequential pages, and the authors are: J. D. WATSON & F. H. C. CRICK; M. H. F. WILKINS, A. R. STOKES & H. R. WILSON; ROSALIND E. FRANKLIN & R. G. GOSLING.http://www.nature.com/nature/journal/v171/n4356/index.html Don't know why that phrase was there, but it looks to me like vandalism. Nick Beeson (talk) 01:00, 25 April 2016 (UTC)
thread_title: Collins

message: The word "booklet" is defined as "a little book with few pages, and a paper cover." The Double Helix was 296 pages, smyth sewn, and hard bound. Very much the definition of a "book". Nick Beeson (talk) 02:00, 25 April 2016 (UTC)
thread_title:  booklet