Talk:Clozapine

message: Most of the article is concerned with potential adverse effects. Just from my own experiences as an inpatient I know it can have very, very positive results. I take it for BPD and it has helped a hell of a lot. 
My psychologist was telling me about a big study in a US psych hospital where a very significant number of treatment-resistant schizophrenic patients recovered enough to leave hospital after a fairly short time on clozapine. There isn't much about the benefits or the studies that proved it was worth prescribing in spite of the side effects. 
Elijah Rosewater  — Preceding unsigned comment added by 109.204.111.61 (talk) 15:44, 19 February 2015 (UTC)
thread_title:  Too negative? 

message: I was looking at the collaborations section on your user page. Are you still interested in improving this article and pushing it through FAC? From experience, drug articles typically require multiple rounds at FAC since they seldom generate input from enough reviewers the first time around. In any event, I noticed you haven't edited this article since 2010, so I'm wondering if you're still willing to commit. Seppi333 (Insert 2¢) 08:48, 10 August 2019 (UTC)
replies: text: I find it hard to get enthusiastic about taking medical articles through the GA?FA process, but I'll take another look. Which just reminds me of another promise I made.Cas Liber (talk · contribs) 09:20, 10 August 2019 (UTC)
thread_title:  FA 

message: Currently, the article states that:
"In 1975, after reports of agranulocytosis leading to death in some clozapine-treated patients, clozapine was voluntarily withdrawn by the manufacturer.[70] ..."
While this appears to be true in some countries (notably Finland), Sandoz AG continued to provide Leponex to patients in Switzerland, Germany and Czechoslovakia, provided that a specialised psychiatrist has prescribed it to them and done the necessary blood work, sharing the results of the haematology with Sandoz research.  This is important, because it helped to estabilish a functioning therapeutic monitoring for a last resort drug, as well as demonstrate that clozapine is both a highly effective antipsychotic and that it can be prescribed to outpatients fairly safely, if the necessary therapeutic monitoring is adhered to.  Cheers,--95.208.240.109 (talk) 22:32, 16 August 2020 (UTC)
thread_title:  Clozapine was not completely withdrawn from the market between 1975 and 1985. 

message: Clozapine is classified as a GABA antagonist and GABA modulator according to CHEBI 
— Preceding unsigned comment added by 79.106.215.39 (talk) 19:49, 10 November 2020 (UTC)
thread_title:  §Clozapine is classified as a GABA antagonist and GABA modulator according to CHEBI (www.ebi.ac.uk)§ 

message: The use of the term "gold standard" in the last sentence of the introduction is confusing. As it's already linked to therapy, wording such as highest indicated drug therapy or first line treatment might be more clear for some. Might need to be rewritten but I'm not comfortable doing that 2605:A601:A184:7800:3BA7:CA5D:6555:206F (talk) 12:25, 1 April 2023 (UTC)
thread_title:  Word choice within introduction 

message: an "advert" tag was applied in a drive-by fashion with no discussion. i removed it. Biosthmors (talk) 12:14, 25 March 2024 (UTC)
thread_title:  "advert"