Talk:Hyperkalemia

message: What about calculating TTKG to aid in the differential diagnosis? Cybergoth 12:18, 27 August 2005 (UTC)
replies: text: Put it in. alteripse 21:34, 27 August 2005 (UTC)

text: I made a TTKG stub. Cybergoth 04:09, 2 September 2005 (UTC)

text: Good pick up.  Andrew73 13:19, 10 March 2006 (UTC)

text: I agree that its very wierd (and funny) to have "lethal injection" there.  But really, its probably the best place for it, rather than creating a separate section for it. :-)  Dan Levy 19:40, 8 November 2007 (UTC)
thread_title: What about calculating TTKG to aid in the differential diagnosis?

message: Increased extracellular potassium will cause hyperpolarization and not depolarization of the cell membrane. dont you agree?
Disagree: Imagine a typical cell which has a membrane voltage determined predominately by conductance through potassium channels.  The point of equilibrium (where the membrane potential will equilibrate) is the Nernst potential for K, which equals -60mV*Log([K]i/[K]o).  As [K]o rises, the membrane will equilibrate at a less negative potential.  Hence, the cell will be depolarized in the setting of hyperkalemia. DanLevy 04:53, 10 June 2006 (UTC)
thread_title:  hyperkalemia wrong information in article 

message: Will delete comment by user 85.167.25.246 regarding Hyperkalemia causing acidosis.  True that cardiac arrest, or weakness of diaphragmatic muscles could lead to hypoxia/ischemia that would cause acidosis, but I think that these would be extreme examples, and the statement is otherwise misleading. Dan Levy 03:26, 12 December 2006 (UTC)
replies: text: ......JFW has reverted the sentence, but I agree with the above author....Is the heart or the brain the most important organ?  Without intracellular calcium, none of our cells would work either.  Abundance is irrelevant.  How about we settle on "a critically important cation."Dan Levy 02:52, 12 January 2007 (UTC)
thread_title:  + 

message: I deleted the phrase: "It can be avoided by using plasma from anticoagulated blood samples, as this will reduce the destruction of cells and platelets during the clotting process." because I think that it was misleading.  It was located right after mentioning the familial pseudohyperkalemias.  In fact, in ref 3 (Blood, 1999) the heparinized blood that incubates for a few hrs shows increased serum [K] over time.  But I think that the statement might apply for thrombocytosis and perhaps it should simply be moved to a different position in the paragraph?  I assume that the best strategy for any suspected case of pseudohyperkalemia would be to spin anticoagulated blood immediately and measure the K from the plasma.  I know that plasma K is always a bit lower than serum K, but would user 205.160.195.36 be able to offer a reference that anticoagulation would specifically be helpful when pseudohyperkalemia is suspected? Dan Levy 22:59, 19 June 2007 (UTC)
replies: text: I think you are correct to have removed it, but would defer to an explicit reference. alteripse 00:04, 20 June 2007 (UTC)
thread_title:  Pseudohyperkalemia 

message: Since the death penalty is contrary to international law and human rights as generally understood, I find it inappropriate to mention its methodology in the context of an article on a medical subject. I would urge the deletion of the relevant paragraph.83.65.178.206 (talk) 10:37, 30 October 2008 (UTC)
replies: text: Interesting point.  Is it really against international law?  Lethal injection is the primary method of execution performed in the USA, which was evidently performed 42 times in the US in 2007.  I wouldn't want to defend my nation's moral/legal system, but I would point out that the mechanism of death from this technique is the same as death from any other cause of hyperkalemia.  So even though physicians are not involved in executions, the section is related to the physiological/pathophysiological condition of hyperkalemia.  Would it be more palatable if the other details of execution were removed, perhaps by deleting thie latter half of the sentence? ("after sodium thiopental has rendered the subject unconscious, then pancuronium bromide has been added to cause paralysis.") Dan Levy (talk) 22:05, 30 October 2008 (UTC)

text: Since the death penalty is still quite real in many countries, including germane information that raises its salience as an issue can lead to a better-informed debate, the foundation for policy re-considerations in those countries where it is still practiced. Knowledge and daylight better foster changes in the marketplace of ideas than ignorance.  —Preceding unsigned comment added by 66.167.61.132 (talk) 22:43, 16 April 2009 (UTC)
thread_title: Execution

message: I agree with user user:Mikael Häggström that it makes more sense to split the TREATMENT section into acute mgmt and prevention.  But I'm not sure what should be done with Kayexalate.  In some patients, it is used chronically to reduce the risk of a hyperkalemic episode, but it also used to remove K from the body in a patient with a mild-to-mod hyperkalemia, such as in the 5.5-6.2 mEq/L range, in a patient who might not otherwise need dialysis.  So wouldn't this *also* be acute treatment?  Suggestions, anyone?  Dan Levy (talk) 14:59, 6 January 2009 (UTC)
thread_title: Acute Treatment versus Prevention

message: Tomato paste is the most-concentrated dietary source of potassium.  —Preceding unsigned comment added by 66.167.61.132 (talk) 22:39, 16 April 2009 (UTC)
thread_title:  Tomato paste as a source 

message: What would be "massive doses of oral KCl supplements", also in terms of tomato paste (twice concentrated)? --Ayacop (talk) 18:10, 1 June 2009 (UTC)
replies: text: Exactly.  I came to this article to find out how much potassium is too much, and went away unsatisfied.  Correctrix (talk) 03:19, 12 August 2015 (UTC)
replies: text: We do not give med doses here typically. Doc James (talk · contribs · email) 06:51, 12 August 2015 (UTC)
thread_title:  How much exactly? 

message: Doc James (talk · contribs · email) 20:51, 28 November 2010 (UTC)
replies: text: seems very practical. JFW | T@lk 21:07, 17 May 2011 (UTC)

text: doi:10.1097/CCM.0b013e31818f222b is good, and gives NNT for many treatments (e.g. NNT for salbutamol is 3!) JFW | T@lk 22:20, 22 October 2011 (UTC)
thread_title: Review

message: doi:10.1002/14651858.CD003235.pub2 - Cochrane review of emergency treatment.
doi:10.1136/bmj.b4114 - BMJ review 2009. JFW | T@lk 14:38, 21 September 2012 (UTC)
replies: text: Am J Med 2015: doi:10.1016/j.amjmed.2015.05.040 JFW | T@lk 20:07, 21 November 2015 (UTC)
thread_title:  More sources 

message: The following resources may be useful in enriching this article:
* 
*  
* Hyponatremia and hyperkalemia By Norbert Lameire
* Emergency lectures - Hyponatremia hyperkalemia
DiptanshuTalk 14:09, 24 June 2013 (UTC)
replies: text: None of those are great WP:MEDRS sources.... JFW | T@lk 11:48, 19 January 2014 (UTC)
thread_title:  Resources 

message: WP:MEDRS-compatible sources are available (I've posted a few above over the last few months) but we're not using them... JFW | T@lk 11:51, 19 January 2014 (UTC)
replies: text: doi:10.1016/j.kint.2015 seems nice. JFW | T@lk 11:23, 22 February 2016 (UTC)
thread_title:  Priorities for updating 

message: I don't see the connection of this sentence to Hyperkalemia. Assuming that there is one, perhaps someone could make it more obvious?
"The combination of abdominal pain, hypoglycemia, and hyperpigmentation—often in the context of other autoimmune disorders—may indicate Addison's disease,[12] which is a medical emergency."
Rick.Wicks (talk) 10:21, 4 October 2016 (UTC)
replies: text: Addison's disease can cause mineralocorticoid deficiency (insufficient aldosterone) which can definitely cause hyperkalaemia. Still, the symptoms can be different from listed here. JFW | T@lk 20:18, 5 October 2016 (UTC)
thread_title:  what's the connection? 

message: Social media has been promoting cream of tartar, a cooking ingredient with the chemical name potassium bitartrate as a cure for several things including Migraines, losing weight etc. "Ingesting extremely high quantities of the chemical is not advisable as it can result in life-threatening cases of hyperkalemia, which is the abnormally high concentration of potassium in the blood."
To keep his brief I just quote Snopes - probably not good enough reference for here - but it mentions the current obsession. I leave to others to consider...
https://www.snopes.com/fact-check/cream-of-tartar-migraine-headaches/
60.242.247.177 (talk) 21:11, 19 December 2018 (UTC)
replies: text: I have only found a single case report: doi:10.1007/s13181-012-0255-x. Probably not heavy enough for inclusion. People with healthy guts and kidneys can handle pretty large amounts of potassium. JFW | T@lk 20:24, 22 December 2018 (UTC)
thread_title:  Popular untested cures. 

message: I understand fast acting insulin (Novorapid to be precise) is used to treat acute hyperkalemia. Especially in a clinical setting where the cause is due to surgery or other treatment. The patient is given an IV solution of Novorapid with glucose (the avoid hypoglycemia due to the extra insulin).
This is done mainly where blood- or other fluid losses- are the cause of the hyperkalemia, not when there is a systemic problem.
Should these two things be included in the article? Fast acting insulin as a treatment and blood cq fluid loss as a cause?
Korporaal1 (talk) 17:35, 10 January 2021 (UTC)
thread_title:  Fast acting insulin and glucose