Talk:Anxiolytic

message: Should it be included here?  It is approved for use in GAD in the European Union PablitoRun (talk) 21:11, 25 May 2010 (UTC)
replies: text: Yes it should be, I have added it here. Thanks for pointing this out. I would encourage you to WP:BEBOLD and just add content to articles as long as it is sourced to a reliable source. :) Also you should add new comment sections to the bottom of talk pages, but not to worry, I spotted it this time. :)--Literaturegeek | T@1k? 22:05, 25 May 2010 (UTC)
thread_title:  pregabalin? 

message: I would not consider beta blockers 'anxiolytic' by definition as they work solely on somatic symptoms. Have amended article but could poss. take out.
:Beta blockers are not anxiolytic per se. However, they can have an anxiolytic effect for some people. The reason for this is that the somatic symptoms frequently end up aggravating the anxiety, which becomes a kind of feedback loop. When the somatic symptoms are alleviated, the anxiety will lessen somewhat for these patients, at least breaking the loop, and occasionally helping the patient to recover from an attack as the relief can aid in restoring mental calm.
:Removing them from the page makes little sense, but one could make a note that they do not have any intrinsic anxiolytic properties, rather having an indirect effect that is useful for some patients. That is to say, they will not calm down a person inhaling a high concentration of carbon dioxide, which the other anxiolytics will do; this is a classic test of efficacy. Note that buspirone has a very limited efficacy, and most people who have tried other anxiolytics report no effect whatsoever if switched over to buspirone.
:Zuiram 03:26, 3 January 2007 (UTC)
thread_title:  Beta blockers 

message: Some of the information on this page appears to be copied from http://www.absoluteastronomy.com/ref/anxiolytic and has been removed by me.
This leaves some 'gaps' in the article, there are several other sentences that have been modified by other posters I've kept in.
To be honest, I think this needs a complete rewrite - the structure was based on the material taken from the webpage and it's not now in any real order. That's why I added the cleanup tag.Berry 18:57, 25 April 2006
:absoluteastronomy is a Wikipedia mirror. This is not a copyright issue. The text could be restored. Colin°Talk 09:41, 27 April 2006 (UTC)
thread_title:  Copyvio? 

message: I have spent some time rewriting this page. Some things to remember for future editors: anxiolytics are agents used to treat the symptoms of anxiety - not an underlying anxiety pathology such as Generalized Anxiety Disorder. A lot of medications seem to have crept into this article that are not anxiolytics (such as neuroleptics). I've weeded them out. Ifnord 20:44, 24 July 2006 (UTC)
replies: text: Thank you!  The link dependence goes to a disambiguation page.  I was going to change it to physical dependence but I wanted to make sure that was what was intended.  I thought "dependence" was used for the physical aspect, and "addiction" for the psychological aspect, but it seems they aren't that well-defined and that it's basically a mess (in usage and on Wikipedia).  Anyway, just wanted to check that it does indeed mean physical dependence here. --Galaxiaad 21:32, 24 July 2006 (UTC)
replies: text: Indeed it's supposed to be physical dependence. I'll correct it. Ifnord 20:10, 25 July 2006 (UTC)
thread_title:  Rewrite 

message: Could someone please add some information about the non-benzodiazepine anxiolytic etifoxine.  It seems Stresam, a popular drug particularly in France for treating anxiety, makes use of this.  Someone I know was on it, so I'm eager to find out more, but there doesn't seem to be info on Wikipedia yet. —The preceding unsigned comment was added by Steve Kroon (talk • contribs) 06:54, 26 March 2007 (UTC)
thread_title:  Etifoxine and Stresam 

message: Opiates were mentioned which while definitely having an instant effect on anxiety are also a drug class all to themselves. (( Perhaps a warning about the extreme addictiveness of opiate drugs (from the relatively safe synthetic codine to definitely not safe 'recreational' class A drugs) would be insulting everyone's intelligence. ))
Etifoxine appears to have effects very similar to benzodiazapines, including having a molecular structure that includes a benzoxazine group - I can't determine if it is significantly different - it appears to be a GABA enhancer which is what benzos are.
There are many substances that have secondary anxiolytic effects and are used to treat GAD and panic symptoms. Several tricyclic antidepressants (eg doxepin) and the non-tricyclic (and extremely unusual) mirtazapine (all by virtue of having antihistamine effects) and most antipsychotic medications have major sedative side effects and they are often prescribed as if they were anxiolyics, usually given in smaller doses than is recommended for their primary use. Both of these classes of drug tend to loose their beneficial side effects after long term use. 
There are several other drugs which have sedative and anxiolytic properties as side effects (one should not confuse sedation with anxiolytic properties as a patient may be quite physically sedated but still experience mental panic or stress - a problem with using antipsychotics for their sedative properties). (( a drug for treating some kinds of parethesia is indicated for panic attacks but I can't remember what it is called )) Even if they belong to another official class of drug, they may be worth a mention as drugs sometimes used in conjunction with more traditional anxiolytic medications, ie the anticonvulsant carbamazepine. Carbamazepine has some popularity as an assistant to antidepressants and anxiolytics.
I don't know what the official status of alcohol is (apart from being a general menace to the community) but, as a drug (ethyl as opposed to cleaning fluid), it is very non specific and prone to paradoxical effects vs being a strong CNS depressant - it can cause rage and mania as well as worsening depression. Also it is rather addictive in some individuals, to state the obvious. But, non-the-less, it acts instantly and often has strong anti-anxiety effects. It's ability to consistently reduce social phobia is well known by any 'social drinker'.
Marijuana also suffers from paradoxical effects vs being a CNS depressant, including causing panic attacks and paranoia. Rage, mood swings and violent behaviour are not known effects, though intoxication and, rarely, psychotic episodes are a problem. I suggest the reference to Marijuana remain as it is for now, though, as always, some citations would be useful (hint hint).
I'll leave it to someone with actual medical training (hehe) to decide for or against additions to this article re medications that touch anxiolytics while not strictly being a part of the classification.  —Preceding unsigned comment added by Jp adelaide (talk • contribs) 15:02, 31 October 2007 (UTC)
replies: text:  This article is not meant to be a guide on taking cannabis. There is noting really wrong in simply stating that cannabidiol is found in cannabis and is an anxiolytic drug. Even though I understand your reasoning I don't think we  should talk about drugs that are not anxiolytic (like THC) in an article about anxiolytics.  Also although I respect your opinion I don't think it's right to state that cannabis cannot be used as an anti-psychotic if that's what you were implying. There are about 1400 different varieties of cannabis, some have low THC values and although THC can induce those symptoms in healthy volunteers, when at such low doses in some varieites of cannabis, and with such high levels of CBD someone could use cannabis as a treatment for schizophrenia because THC does have theareputic effects. Cannabis has been used to treat anxiety disorders in the past, it's used to treat social anxiety disorders at least that I know. Also, there are what about 400 different chemicals in cannabis? I'm sure some others have anxiolytic type effects, but the main thing to point out is cannabdiol is only second to THC in quantity and as I've pointed out, in some varieties there is more CBD than THC, thus any negative effect of THC is cancelled out, and that's not original research the article itself aludes to this. Supposed (talk) 04:10, 19 May 2008 (UTC)
thread_title:  Other related medications where anxiety is not indicated 

message: Why is this drug not mentioned? TimL (talk) 13:36, 17 May 2008 (UTC)
thread_title:  [[Hydroxyzine]]? 

message: http://en.wikipedia.org/wiki/Coriander links to this page but is not listed under the Herbal section, if someone could edit that in properly.  I don't know how.  64.105.35.105 (talk) 09:39, 22 May 2008 (UTC)
thread_title:  Herbal treatments 

message: "Benzodiazepines are prescribed for short-term relief of severe and disabling anxiety"
This seems a bit of  asweeping statement - benzos arnt always prescribed for short term use only, and they are sometimes used for moderate as opposed to severe, disabeling anxiety
121.209.52.159 (talk) 01:55, 30 March 2010 (UTC)
replies: text: If you have a reference you can cite what you are saying in the article.--Literaturegeek | T@1k? 00:07, 31 March 2010 (UTC)
thread_title:  Benzodiazepines 

message: Really?  This article http://www.ncbi.nlm.nih.gov/pubmed/12652886 on lateriflora says valerian, kava-kava, St. John's Wort, passion flower, and hops have all been shown effective in double blind controlled studies.  — Preceding unsigned comment added by 96.224.73.39 (talk) 19:27, 17 July 2011 (UTC)
thread_title:  As of 2006, only Kava and Brahmi have shown anxiolytic effects in randomized clinical trials, and only Kava's effect has been independently replicated 

message: alpha-2 adrenoreceptor agonists such as clonidine and detomidine are indicated as sedatives and can produce a significant anxiolytic effect by preventing the release of adrenaline in both the CNS and PNS, reliving both the psychological and physiological symptoms of anxiety, they are sometimes used clinically for treating anxiety disorders with positive evidence from RCT's also. Would be nice if someone could add this class of drugs to the list sometime. 151.225.64.244 (talk) 23:02, 30 September 2014 (UTC)
thread_title:  a2 agonists 

message: Though no doctor would prescribe them for anxiety they certainly have anxiolytic properties.
http://www.ncbi.nlm.nih.gov/pubmed/25544740  — Preceding unsigned comment added by 78.146.5.156 (talk) 08:03, 17 March 2015 (UTC)
thread_title:  Opiates / Opioids 

message: Anti epileptic medications (lamictal, Tegretol, topamax, pregabalin, etc) have been used for anxiety in doses lower than the anti-convulsant doses. When I've tried creating a category for them it got deleted.
I don't want to go through the trouble of creating the category again if it is just going to be deleted, so why is it deleted? If anything, anti-convulsants are a more mainstream therapy for anxiety than opioids, and opioids have their own category.
:This article is a mess. In fact, at first reading I was surprised that anything else than benzos and barbs are treated in detail. Much more limited definitions on what anxiolytics are, exist: . Opioids definitely shouldn't be included.Miacek  (talk) 16:16, 10 May 2018 (UTC)
replies: text: I agree that opioids should not be included. 2600:6C5E:107F:701:D8B8:B863:6089:AA05 (talk) 12:00, 19 September 2022 (UTC)
thread_title:  Why does discussion about anti-epileptics keep getting deleted 

message: Its placement and availability had seemed to be on the rise, but now, rather suddenly it seems, it has just as simply and swiftly 'disappeared'...? 
173.72.129.248 (talk) 04:40, 26 May 2022 (UTC)
thread_title:  Whatever happened to the little audio button that helped in the pronunciation of so many words? 

message: I propose merging anti-anxiety medication into anxiolytic. I think the content in anti-anxiety medication, which includes more history and context, can be easily added to anxiolytic, which currently is more focused on discussing specific medications. I don't anticipate article size or weighting problems. I'm rather new around here, and I'm not an expert on anxiety meds, so please let me know if I'm totally off base. Thanks! Crunchydillpickle (talk) 15:13, 2 June 2022 (UTC)
replies: text: This seems like a good idea to me.  The articles seem to be covering the same topic. I'm not an expert on anxiety meds, and I've never merged articles, but this seems to make sense here. Cheers! Doctormatt (talk) 17:59, 2 June 2022 (UTC)

text: Support. These articles cover the same topic. It's quite a big job to merge them both, though! I think that "anti-anxiety medication" should be merged into "anxiolytic", mostly preserving the drug descriptions from "anxiolytic" but adding the "Nature", "Aetiology", and "Clinical Use" sections from "anti-anxiety medication. Bibeyjj (talk) 16:16, 9 June 2022 (UTC)

text: Support appear to cover the same subject matter. Graeme Bartlett (talk) 09:50, 8 July 2022 (UTC)

text: Anxiolytic and anti-anxiety are synonymous, so I agree the two pages should be merged. Mjǫðr (talk) 22:07, 30 July 2022 (UTC)
thread_title:  Merger proposal  

message: Please note that an article was created attempting but failing to duplicate content from this article. I have since redirected it here. TheTechnician27 (Talk page) 23:59, 11 August 2023 (UTC)
thread_title:  '[[List of anxiolytics]]'