lflage/wiki-talks huggingface dataset:
Talk:FOX proteins

message: I annotated the list of FOX genes at the bottom to help people find the FOX gene they need more easily.  It's a little cluttery; I could turn it into a table if anybody thinks it's neccessary....just let me know  doctorwolfie (talk) 13:09, 2 December 2011 (UTC)
thread_title: Annotations

message: I suspect that foxpd6 should be just foxd6 Noremacsemaj (talk) 10:30, 15 August 2008 (UTC)
replies: text: I suspect you're right - I'll be bold. -- 216.250.179.37 (talk) 00:53, 14 September 2008 (UTC)
thread_title:  fox protein foxpd6
Talk:Protein isoform

message: Can the first sentence of this article be rewritten so that the definition does not contain the defined term?
69.140.152.55 (talk) 02:13, 18 May 2008 (UTC)
thread_title:  definition 

message: Hi everyone,
I plan to expand this stub by adding some sections: definition and mechanism. And I will rewrite the 1st paragraph in the beginning of the page and change the title of the section glycoforms. I will also add some references that I was used in the editing. I think some figures from alternative splicing article is very useful in this page. So I may add some figures in mechanism section. 
I will upload my work some time next week.
Jack1104ch (talk) 17:55, 1 April 2016 (UTC)
thread_title:  Hi 

message: The introductory sentence says that the term "isoform" is ambiguous, as it describes two different concepts: "one-gene-multiple-proteins" and "multiple-genes-similar-proteins". But then in the rest of the article it's not clear which of the two concepts is being described. Most of the article seems to talk about the "one-gene-multiple-proteins" concept via alternative splicing, but the AMPK example in the definition section seems to refer to the "multiple-genes-similar-proteins" concept. This is very confusing. AxelBoldt (talk) 14:36, 4 April 2017 (UTC)
replies: text: I rewrote the lead to clear up the definition. See if it helps.  --Mark viking (talk) 21:18, 4 April 2017 (UTC)
replies: text:  this is a lot better, thanks! AxelBoldt (talk) 20:10, 5 April 2017 (UTC)
thread_title:  Definition unclear 

message: Hi 2405:204:109C:AEEF:7EE6:26FF:830D:7590 (talk) 15:41, 9 February 2022 (UTC)
thread_title:  Table
Talk:Ruth Barnett

message: This concerns POV tag cleanup.  Whenever an POV tag is placed, it is necessary to also post a message in the discussion section stating clearly why it is thought the article does not comply with POV guidelines, and suggestions for how to improve it.  This permits discussion and consensus among editors.  From WP tag policy: Drive-by tagging is strongly discouraged. The editor who adds the tag must address the issues on the talk page, pointing to specific issues that are actionable within the content policies, namely Wikipedia:Neutral point of view, Wikipedia:Verifiability, Wikipedia:No original research and Wikipedia:Biographies of living persons. Simply being of the opinion that a page is not neutral is not sufficient to justify the addition of the tag. Tags should be added as a last resort.  Better yet, edit the topic yourself with the improvements.  This statement is not a judgement of content, it is only a cleanup of frivolously and/or arbitrarily placed tags.  No discussion, no tag.Jjdon (talk) 19:43, 1 May 2008 (UTC)
thread_title:  POV tag
Talk:SUMO protein

message: Please, give the phonetic transcription of the word "Sumoylation".
93.81.94.22 (talk) 20:02, 10 June 2009 (UTC)
thread_title: Untitled

message: I deleted the following from the SUMO attachment section. It should be converted to full sentences with citations if it is relevant and correct.
balance SUMO equilibrium is important for the cell.
Reduced or enhanced SUMOlyation will lead to onsets of cancers,
for example,
prostat cancer lead to eleveated expression of SENP1 or SENP3,
breast cancer increased modification of SUMO targets via,
(I)induction of Ubc9 E2 ligase
(II)PIAS3 E3 ligase
(III)cocurrent decrease in SENP6
Biolprof (talk) 17:40, 17 August 2012 (UTC)
thread_title:  deleted sentence fragments
Talk:Jessie R. Fauset

message: "one of whom passes for white until radicalized by an experience in Arkansas which is described in retrospect" - this phrase in the article is in a parenthetical description for There is Confusion.  The character referred to is a minor one and I wonder if this description doesn't give a skewed picture of the book.  However, I'm not up on the criticism of the book, so I don't know if this character (Vera Manning) is generally called attention to in this way or not as a more memorable feature of the book, or something like that, so I didn't want to remove the description immediately.  If there's no objection, I will probably remove it and perhaps give a more generalized description. faithx5 04:53, 14 February 2007 (UTC)
thread_title: There is Confusion description

message: Her name is spelled in two ways (Redmon/Redmond), without any explanation, and appears in sources as Redmon. What is the justification and cite for using Redmond (as on her photo)?Parkwells (talk) 14:29, 3 June 2016 (UTC)
thread_title: Confusion about spelling of name
Talk:New Zealand women's national rugby union team

message: Just as an irrelevant point, it severely annoys me that the name of the article was changed to be "consistent" with the ridiculous decision to name the All Black page the "NZ National Rugby Team" page. It's simply the All Blacks that is NZ's national rugby team. I note that the Red Socks is not called the "Boston Basketball Team" page. It's not as if a search for "NZ women's rugby team" wouldn't return the Black Ferns in any case. Trxi (talk) 14:04, 9 August 2009 (UTC)
thread_title: Article name

message: It' be great if more people who have better knowledge about the team helped keep this page up to date. 
* Please check where links go when you make them - "World Cup" took you to the men's world cup.
* The Farah Palmer Cup article was not linked, and still showed up everywhere as the "NPC" (should have been the WPC)
* For the current World Cup (2017) team, I've guessed at the best positions for the players - it'd be better if they were represented at the positions they predominately played during the event. Unfortunately, in the template, there's no position for "utility back".
Trxi (talk) 12:20, 26 December 2017 (UTC)
thread_title: Expert contributions please 
Talk:RNA-dependent RNA polymerase

message: I'm going to move the section on VPg to the Picornavirus article because it is too specific for this article. Xenobiologista (talk) 18:46, 17 February 2014 (UTC)
thread_title: Moving VPg

message: Would anyone mind if I renamed this article to RNA-dependent RNA polymerase and merged RNA replicase into it? Narayanese (talk) 13:02, 29 March 2008 (UTC)
thread_title: Merge/Rename?

message: And what about plant RNA-dependent RNA polymerases?  — Preceding unsigned comment added by 195.113.47.253 (talk) 09:37, 4 December 2015 (UTC)
thread_title:  Plant RDR 

message: Some RNA viruses, such as corona viruses, do proofreading on their RNA polymerase. I don't know if it is part of the polymerase itself, or a separate protein. (Or separate subunit.) As the article indicates, the error rate of the usual RdRp is about 1 in 10,000, which is fine for smaller viruses, but too high for larger ones, like corona viruses. There is, then, now much interest in the workings of corona viruses such as Covid-19. This article could either mention it, or link to an article which does. Gah4 (talk) 23:40, 11 January 2022 (UTC)
thread_title:  proofreading 

message: How is “RdRp” pronounced?
One part of the article uses “a RdRp” which implies that it is pronounced with a starting consonant sound (“a redrip”, perhaps?) and not “ar dee ar pee” or “ar en ay-dependent…”. pne (talk) 05:46, 7 August 2022 (UTC)
thread_title:  Pronunciation of “RdRp”
Talk:Memory transfer

message: "Memory RNA made some appearances in the science fiction of the time," but the article never states what "the time" was. When was memory RNA hypothesized, and when and how was it discredited? WaxTadpole (talk) 22:57, 5 March 2013 (UTC)
thread_title:  When? 

message: New research probably has the same flaws and would be explained with similar alternative explanations.--Extremophile (talk) 18:21, 19 July 2013 (UTC)
thread_title:  Decapitated worms grow heads with old memories, say scientists 

message: Suggest incorporate new information from http://www.bbc.co.uk/news/science-environment-44111476 wherein RNA extracted from Aplysia sensitised to a shock stimulus resulted in sensitisation when injected into control non-shocked animals.TiredOfLondon (talk) 02:28, 22 May 2018 (UTC)
replies: text: Paper can be found at.https://www.ncbi.nlm.nih.gov/pubmed/29789810 They transferred sensitization. I wouldn't go so far as to call that a "memory".--Crackwitz (talk) 02:27, 31 March 2019 (UTC)
thread_title:  RNA and memory transfer in Aplysia
Talk:Methylation specific oligonucleotide microarray

message: Hi, my friend and I wrote out a more detailed, expanded version about this MSO microarray technique.
Here is the link to our sandbox:
https://en.wikipedia.org/wiki/User:Ash0885/sandbox
Thanks in advance for checking it out!  — Preceding unsigned comment added by Ash0885 (talk • contribs) 05:00, 7 November 2019 (UTC)
thread_title:  expansion of this stub
Talk:Locked nucleic acid

message: Ok this is possibly my first edit/talk on wiki so go easy if I'm not following the rules. First of all is it right that the second synthesis is listed after the first one in the initial paragraph (i.e. LNA was independently synthesized by the group of Jesper Wengel[3] in 1998, soon after the first synthesis by the group of Takeshi Imanishi[4]. You would think you would acknowledge the authors of the first synthesis first. Also I'm not sure that reference 3 is actually the first report of this by the authors. I believe the first is in the RSC journal Chemical Communications (http://pubs.rsc.org/en/content/articlelanding/1998/cc/a708608c) where the report was submitted to this journal one month before it was submitted to the tetrahedron journal. I should declare for openness and transparency that I am an editor for Chemical Communications (searching through old articles is how I came across this) however I don't believe this changes the facts of the submission date and I believe that due recognition should be given to the original source.  — Preceding unsigned comment added by RossMcL1 (talk • contribs) 16:01, 14 September 2012 (UTC)
thread_title: Untitled
Talk:Gene knockdown

message: I added references and removed the "unreferenced" tag (but forgot to log in first).  JonMoulton (talk) 17:40, 25 April 2008 (UTC)
thread_title: Untitled

message: I would like to add a redirect from the term "Knockdown Mutant" to this page (once I learn how to make redirects that is).
If I don't hear from anyone who is against it I will assume its alright. Colincbn (talk) 07:28, 2 April 2009 (UTC)
thread_title: Knockdown Mutant

message: What are the main differences between knockouts and transient knockdowns (apart from DNA change vs no DNA change)?  Will the phenotype be the same?  pgr94 (talk) 13:07, 27 December 2010 (UTC)
replies: text: Did some digging: In these articles  , there is a comparison of one gene in mice (knockdown vs knockout).  Under the same conditions a difference in phenotype was observed.  This article  reports "Array analysis revealed remarkable parallelism of transcriptomic changes in knockout and knockdown astrocytes, with similarly altered genes being located on all chromosomes and encoding proteins involved in a wide diversity of cell functions."   pgr94 (talk) 14:19, 27 December 2010 (UTC)
thread_title:  What are the differences between knockouts and transient knockdowns? 

message: This section is written like an ad. Should it be removed? 12.31.231.168 (talk) 17:34, 11 March 2015 (UTC)
thread_title:  Commercialization Section 

message: The DNA changes induced by gene editing technologies lead to knockouts, not knockdowns.  I don't understand why they are being duscussed on a page titled Gene Knockdown. Knockdowns are either genes modified at DNA level for reduced expression or technologies that halt gene expression at the RNA level (e.g. RNAi or antisense).
JonMoulton (talk) 20:27, 22 October 2015 (UTC)
thread_title: Why discuss CRISPr and TALEN knockouts on a knockdown page?
Talk:Site-directed mutagenesis

message: The introduction to this page gives a decent overview of what site-directed mutagenesis is, but it lacked a lot of detail that would have been beneficial to understanding why a scientist might utilize site-related mutagenesis. The introduction also needed to cite more if the information. There was only one reference used in the entire introduction. 
The "history" section used a good amount of citations, but it was too short and did not have enough information. It should have included more up to date information about current uses of and research on site-related mutagenesis. 
The "basic mechanism" section was slightly confusing. If it was described in a more stepwise manner it would have been more clear and easier to follow, as if the reader was following a protocol. 
The "Approaches" section was well done and included valuable information. It was interesting to read about the different site-related mutation methods that have developed over time. The descriptions about each method provided a good background about the methods. The CRISPR section needs more information, especially because it is such an important and controversial method of genetic engineering. 
The "applications" sectioned lacked a lot of possible applications. 
The references I visited were all relevant, peer-reviewed, and were found in scientific journals. 
The tone of the article was neutral and scientific.
Ddesalvo2016 (talk) 14:08, 29 August 2019 (UTC)
thread_title: Untitled
Talk:Credits (science fiction)

message: How about a listing of explicit series that use the Credit system, alternatives to Credits (not considering incarnates of "the dollar"), and methods of which these credits are often seen to be transferred?
For example, using credit cards that literally contain the money, credit "chits" that act as reusable containers for credit(s), or others? 130.194.13.104 02:03, 19 June 2007 (UTC)
thread_title: Untitled
Talk:Directionality (molecular biology)

message: The article Upstream and downstream (DNA) duplicates information found on this page.  It is also short and confusing.  Should they be merged? d20 (talk) 16:57, 17 February 2016 (UTC)
thread_title:  Merge articles? 

message: It should also be pointed out that the 3' A tailing of active mRNA is only something that Eukaryotes do. Most Bacteria and Archaea can polyadenylate RNA, but they usually do it to flag it for degradation.128.175.254.131 (talk) 05:45, 14 April 2011 (UTC)
replies: text: Why not edit the article to say so? (Preferably adding a suitable reference, which this article needs more of anyway.) Remember the Wikipedia mantra:  Be Bold! yoyo (talk) 16:51, 21 June 2012 (UTC)
thread_title:  Polyadenylation
Talk:Julie Kedzie

message: Removing Notability box as the following two criteria appear met...
Wikipedia:Notability (people)#People still alive - To quote from the entry for sportspeople/athletes: "Sportspeople/athletes who have played in a fully professional league, or a competition of equivalent standing in a non-league sport such as swimming, or at the highest level in mainly amateur sports, including college sports in the United States." At face value, this would appear to include most professional mixed martial artists, but in practice should probably include those who have had at least one, and preferably several fights in an established professional fight promotion (e.g. not a startup promotion). 
Wikipedia:Google Test should also prove to be a practical test of notability.
Good looks? *cough, splutter* -- Ghostreveries 12:27, 6 March 2007 (UTC)
thread_title: Untitled
Talk:Harry Brookes Allen

message: Please don't link to every single name. Thomas Watts Allen, for example, doesn't seem to have any significance other than being HBA's father, so why give him a redlink? And is the Harry Mason linked to actually the right one? If not, and if HM is not significant on his own account again there should not be a redlink. 81.159.56.126 05:07, 14 February 2007 (UTC)
thread_title:  Links
Talk:Nucleic acid hybridization

message: I saw that hybridisation (molecular biology) redirects here. Shouldn't it be the other way around? Molecular hybridization would also include RNA probes (e.g. labeled by in-vitro transcription) and RNA-RNA and RNA-DNA hybridization on Northern and Southern blots. - tameeria 17:43, 14 April 2007 (UTC)
replies: text: I agree, we need to rename and add stuff about the other kinds of nucleic acid hybridisation. (Million_Moments 14:40, 20 April 2007 (UTC)
thread_title:  RNA hybridization? 

message: I'm suggesting to move this page to nucleic acid hybridization since that is the term I have found in intro-bio textbooks. Alternatively, I propose to exchange the content of this page and hybridisation (molecular biology). If anyone has any concerns or comments, please voice them here. - tameeria 19:30, 7 May 2007 (UTC)
thread_title: Requested move

message: In the see also section, there is a link to the disambiguation page for homology. Not being a biologist, I can see several options on that page that might be relevant to this page - Homology (biology) and Homology modeling. Could someone who knows more about the subject please link it directly to the one that is correct? Thanks, Kastrel (talk) 14:03, 25 March 2008 (UTC)
thread_title: Homology

message: im searching for dna-rna bonding (ssRNA and ssDNA together in a doble helix)
any citation to an article about that would be welcome
me85.74.186.244 (talk) 08:21, 5 March 2020 (UTC)
thread_title:  Help 

message: I'm not well studied just think alot and after reading some pages wonder if anyone thinks it's possible to introduce certain bio ...?... Into a unknowing studied group through something like methamphetamine?
First phase would include a temp. Lowering affect second phase would be temp. Rising affect to manipulate the DNA or RNA in a manner that would produce results with or without adverse affects do to the fact they are self inducing through personal addiction? Caspergreenmoreknow1edfe (talk) 06:21, 8 December 2022 (UTC)
thread_title:  Inner body testing through street drug induction and hybridization.
Talk:Dunton station

message: I'm not sure if Montauk Branch trains actually served this station (post-reopening), but I don't see why not. --NE2 05:18, 14 February 2007 (UTC)
replies: text: Never mind; this summer 1897 timetable shows some stopping there. I'd really like to know when the Main Line stopped serving Dunton. --NE2 05:22, 14 February 2007 (UTC)

message: I didn't think the Atlantic Tunnel had anything to do with Dunton Station, considering that it starts west of the Morris Park Facility. The only tunnel I can think of here is being used for the IND Archer Avenue Line. Maybe Dunton station was closed in conjunction with all the others being closed due to the Atlantic Tunnel, but not because of the tunnel. ----DanTD (talk) 12:30, 2 September 2010 (UTC)
thread_title:  Atlantic Tunnel? Here? 
Talk:List of Boston Legal characters

message: Shouldn't Katie Lloyd have a section here? The character was a large part of the last two seasons.N9jig (talk) 10:17, 13 April 2017 (UTC)
thread_title:  Katie Lloyd 

message: Until an episode is actually aired to show otherwise, I think it would be prudent to leave him in the main characters section.  On more than one occasion characters have "left" their position on a show only to either return within a couple episodes or remain just as prevalent in a different role.  If you need a good example, consult NCIS (TV series).  The character Leroy Jethro Gibbs "left" the show in a season finale, only to show up as a character in the season premier and return to his position within NCIS within 3 or 4 episodes.--Oni Ookami AlfadorTalk|@ 05:08, 14 February 2007 (UTC)
replies: text: I believe that the definition of a main character corresponds with the opening credits, does it not? Hearfourmewesique (talk) 22:49, 6 May 2012 (UTC)
thread_title:  Jeffrey Coho as a main character 

message: It is rather odd that Carl Sack is not listed anywhere in this page. I added him to the main characters section. --144.36.234.233 (talk) 06:17, 11 February 2010 (UTC)
thread_title:  Carl Sack 

message: He was not in the main credits of the first season, how come he appears as "main" in the table? Hearfourmewesique (talk) 16:32, 6 May 2012 (UTC)
thread_title:  Auberjonois
Talk:Granule (cell biology)

message: I am a Cell Biology student in BIO 401. I will critique the page as presented and then make a submission in areas that can be further explained and researched with reliable references. Everything presented is relevant to the page title, without any distracting facts or information. The article is neutral, without any biased standpoints. The references are reliable, but more references can be added in all areas, especially related to granules in plant cells. Images should also be added to help create further clarification as to what granules look like in each sub-topic listed on the page. 
The Leukocyte section does not have a reference connected to the information presented, so further investigation of this section can only further the accuracy of the information and clarification for readers. The direct links to other wikipedia pages does help support the information provided in the Leukocyte sub-topic, if readers are looking for more in depth information. 
A possible addition to this section, or start of a new section, since the immune system is mentioned, could be Mast cells. Mast cells, although not a Leukocyte, play a role in the immune system and have secretory granules. Other wikipedia pages can be connected to this section to help create further clarification of the role these granules play and on aspects that are outside the scope of granules for readers looking for further information.
Another possible idea/sub-topic to add to this page could be from a histological standpoint. Nissl Bodies for example, found in neurons, have granules. An image can be provided of this, along with supporting information as to what these granules actually are and the staining needed to view them. The Nissl body wikipedia page can be connected to this section for readers to obtain further information on there exact function in the nervous system.  
Overall, this page is easy to read, without mistakes, and has many opportunities for possible expansion that can connect this page to other wikipedia pages and references for the most accurate information for readers seeking knowledge on this topic. Doglover93 (talk) 15:53, 27 October 2015 (UTC)
thread_title:  Cell Biology Student Critique 

message: Kdidhud 119.2.118.6 (talk) 15:03, 8 March 2023 (UTC)
thread_title:  Granules 

message: — Assignment last updated by BusyBee222 (talk) 14:34, 6 February 2024 (UTC)
thread_title: Wiki Education assignment: Bio 401 Cell Biology S2024

message: I am also a cell bio student looking to improve this article! My plan is to add and expand upon the existing sections. Moreover, I noticed some of the original content contains rogue reference subscripts, and I worry that the information has been copied and pasted from somewhere. I plan to fix this, as well! BusyBee222 (talk) 02:33, 7 April 2024 (UTC)
thread_title:  Cell Bio Student Edit
Talk:Tether (cell biology)

message: This article seems to talk about a physical cellular process where a tether is produced by the cell membrane, and also a biochemical term categorising a type of molecule by its function. If someone with more knowledge on the topic could confirm, it looks like this should be two pages. Bluescreening (talk) 18:43, 6 May 2024 (UTC)
thread_title:  Split proposed