Talk:Antigen-presenting cell

message: Is there somebody that know, if there is rules for whis sequences are presented by APCs? If yes, can he describe it to page of Antigen-presenting cell? Thanks. Bal.
As well, there are specialized cells in particular organs (e.g., microglia in the brain, Kupffer cells in the liver), derived from macrophages that are also effective APCs.
I deleted this this because microglia, Kupffer cells, histocytes, osteoclasts, etc are just specific names for macrophages found in particular locations, and it is redundunt to mention them again.  —Preceding unsigned comment added by 99.232.233.87 (talk) 18:02, 16 July 2008 (UTC)
thread_title: Untitled

message: The line reads:
"B-cells, which expresses (as B cell receptor) and secretes a specific antibody, can internalize the antigen which bind to its BCR and present it incorporated to MHC II molecule, but are inefficient APC for most other antigens."
This line never states what type of antigen the B is picking up, so it's conclusion that it is not an effective APC for most other antigens is confusing.  Can anyone clarify this?  —Preceding unsigned comment added by Mizower (talk • contribs) 01:43, 16 October 2010 (UTC)
thread_title:  Line about B cells as APC doesn't make sense 

message: This text, in a bullet within the Professional APCs section, is unclear:
Macrophages, which are also CD4+ cells and are therefore susceptible to infection by HIV as well, since HIV invades immune cells through CD4+ receptor interactions.
I'm studying this, and from what I've read elsewhere, macrophages aren't "CD4+ cells", but cells with exhibit the CD4 complex on their cell membrane.  Since T-Helper cells are often referred to as "CD4+ T Helper cells" (e.g., in the introduction to CD4), the text as it stands can be read to imply that a macrophage is a type of T-cell.  I'm not far enough along in my studies to want to correct this myself, however.  — Preceding unsigned comment added by 71.198.248.252 (talk) 07:28, 17 October 2014 (UTC)
thread_title:  Macrophage somewhat implied to be a T-cell? 

message: I've been assigned to work on this page. I'm planning to add a few new sections and lots of new information. This is my bibliography as it stands right now; any questions or comments are welcome. 
Immcarle6 (talk) 20:57, 2 February 2016 (UTC)
thread_title: Updating and adding new sections to the page

message: I think that the illustration in the upper-left corner of this page is misleading. Maturation is the process that occurs in the thymus when thymocytes are exposed to APCs displaying self-antigens. Most thymocytes die (apoptose) as a result of this process, whereas the survivors "mature". Outside of the thymus, APCs displaying non-self antigens cause T-cells to become activated against the antigen, thereby resulting in destruction of the pathogen by the adaptive immune system. --Ben Best:Talk 14:04, 24 December 2019 (UTC)
thread_title: Maturation versus Activation

message: In the second paragraph of the lead we have a sentence beginning, "Professional antigen-presenting cells, including macrophages, B cells and dendritic cells, present foreign antigens to helper T cells,..."
Is the word "Professional" being used in a subject specific way here with which I am unfamiliar, or is it simply a poor choice of word? Hedles (talk) 17:03, 20 February 2021 (UTC)
thread_title:  Professional antigen-presenting cells