Talk:Cell membrane

message: Use another website
a cell wall is a biological membrane that  helps the cell seperate all the interior of a cells. come on people gosh just stupid I mean like what the heck.
Not written by the above writer.
If the cell membrane (plasma membrane) "is a biological membrane that separates the interior of all cells from the outside environment," then does such a definition make it seem that the cell wall of a cell is in the "outside environment"?  Perhaps the definition should be concerned with the cytoplasm--for example, "the plasma membrane surrounds the cytoplasm."
Also, if the cell in the associated diagram contains cholesterol, then must it not be some type of animal cell?  And if it is an animal cell, then should the diagram be entitled "Animal-cell membrane" rather than "Cell membrane"?  And should "Illustration of a Eukaryotic cell membrane" read instead "Illustration of a Eukaryotic animal-cell membrane"?  — Preceding unsigned comment added by Yurugu (talk • contribs) 12:58, 23 June 2014 (UTC)
thread_title: Untitled

message: Can someone well-versed on this topic incorporate Caveolae into this article? Kingturtle 00:08 May 14, 2003 (UTC)
No I can't help you out, Kingturtle...I'm sorry.  If you are a teacher, I strongly recommend this site to your students.  I am a high schooler in biology and have found this site very helpful in looking up words and information.  Plus, it's free!!  I strongly recommend it!  Happy exploring with Wikipedia!!!!
:I think it's worth having a separate article; research in the field is ongoing and the caveolae article could potentially expand considerably.  It should be linked from here, though; it it?  I'll check.  --Chinasaur 00:39, 8 Sep 2004 (UTC)
thread_title: Caveolae

message: I can't do it right now, but someone should add a section to this article about: 1) junctions between the cell membrane (i.e. desmosomes, tight junctions, hemidesmosomes, etc.) 2) all three transports (right now there are only two - all three are simple, facilitated, and active).
:I also can't do it right now, but someone should add a section on apical and basolateral membrane, and redirects too. --Eleassar777 14:34, 24 May 2005 (UTC)
thread_title:  Transport 

message: I added today an article about polymersomes and checked out the liposome article. Both are currently stubs. I don't have the expertise required to write about them beyond what I already wrote (and that's not much and probably lacking in various aspects) but it would be nice if someone qualified could write them.
Link to this article should be added as well, as should links to them be added to this article. I'd also be very pleased if someone could start an article about artificial cells. --Khokkanen 10:34, 12 July 2005 (UTC)
thread_title:  Artificial outer membranes 

message: This needs to be improved. I inserted a few phrases, please fell free to edit anything. Note that biological membranes include carbohydrate component, in addition to lipids and proteins. Biophys 02:45, 30 January 2007 (UTC)
thread_title: Structure of biological membranes

message: Fluid mosaic model redirects here. I think it might be better to add that topic to biological membrane though, for the simple reasion that it is more general while this article is the more specific case. A cell has other membranes besides its plasma membrane, but the lipid bilayer/fluid mosaic model applies to all of them. - tameeria 04:24, 9 March 2007 (UTC)
thread_title:  Fluid mosaic model 

message: This picture is not correct. The legend of this figure sounds weird to me. I've got the impression it mixes different systems of protein classification: the integral protein is globular, the transmembrane helix is intergral, the channel protein is a transport protein, peripheral protein are different from surface protein... that's very confusing! The term "globular" is rarely, if not never, used for membrane proteins. It qualifies the shape of (soluble) proteins. Actually, this is the opposite of "fibrous proteins". The integral proteins, as shown on the picture, are bi/polytopic proteins in fact. Integral means "tighly bound to the membrane", and not necessarly transmembrane. In the same idea, "peripheral" means "not tighly bound to the membrane". Only biochemical tests can say if the case for a specific protein... So the "peripheral" protein showm in the picture is in fact a monotopic protein. That's all you can say without performing tests. Actually, the surface protein is probably also a peripheral proteins. Finally, cholesterols look oriented in the wrong sense with their aliphatic tails oreitned toward the hydrophilic heads of phospholipids. cheers. -- 22:56, 23 April 2007 (UTC)
replies: text: also, "peripheral" is spelt wrong Crana 11:10, 7 May 2007 (UTC)
thread_title:  Illustration of a cell membrane 

message: I'm proposing to merge the contents of the article Protein Function in Cell Membranes either into this one or into membrane protein. - tameeria (talk) 02:22, 9 December 2007 (UTC)
replies: text: I'm behind you on that. I think that membrane protein would be the more appropriate place to merge it. – ClockworkSoul 05:13, 19 April 2008 (UTC)
replies: text: I just did it, there was very little in "Protein Function" to salvage.Biophys (talk) 00:43, 20 April 2009 (UTC)
thread_title:  Protein functions in cell membranes 

message: In the article, it says there are different type of cell membrane in different cells. In effect, does it mean a plant cell's membrane have the different composition than an animal's cell's membrane? And should we state it?Rider555 (talk) 02:25, 19 April 2008 (UTC)
thread_title: Cell Membrane Difference

message: I did significant work on the cell membrane image when it was a Featured Picture Candidate and thought that the article could benefit from it. It shows the membrane more clearly and places it in context within the cell. Also shown are a more detailed view of the bilayer and phospholipids that make up a critical part of the membrane. If you have any corrections or suggestions I would like to hear them. Dhatfield (talk) 15:43, 18 June 2008 (UTC)
thread_title:  New diagram of cell membrane 

message: This page is a very in depth view of the cell membrane, scientifically precise etc. But it's hugely daunting to someone without a deep biological background. There's no link to an alternative laymans version of the page, and simple english wikipedia's version has barely any content. Any chance of some of you working on either a laymans wiki page under a slight variant name (I'm not sure how standard they are, but maths articles often do so) or working on the Simple English version? -94.192.232.74 (talk) 16:19, 28 March 2009 (UTC)
replies: text: Agreed. This is a subject I do understand, but I still think it should be more accessible. There's no point in having an article if the only people who can understand it are the people who already know the topic.  —Preceding unsigned comment added by 138.78.98.200 (talk) 17:14, 6 April 2009 (UTC)
thread_title: A non-technical alternative?

message: The high molecular percentage of cholesterol required by  membranes (20% molecular) and lipid rafts (up to 50% molecular)makes its absence from lipid membrane text and diagrams one of the huge enigmas of modern cell membrane science.
Most trans-membrane functions will seriously slow down if cholesterol is reduced by 9%.
example:
Author: Waseem, Tatyana V;Kolos, Viktoriya A;Lapatsina, Liudmila P;Fedorovich, Sergei V
Title: Influence of cholesterol depletion in plasma membrane of rat brain synaptosomes on calcium-dependent and calcium-independent exocytosis
Journal: Neurosci Lett
Volume: 405
Year: 2006
Pages: 106-10
http://view.ncbi.nlm.nih.gov/pubmed/16835010
Glynwiki (talk) 16:49, 30 May 2009 (UTC)
thread_title:  Membrane Cholesterol 

message: I've never heard the term "mandoflorpes", let alone in conjunction with the plasma membrane.  A Google search  for the term yields no results apart from this page and pages that have obviously copied this page word-for-word.  Is this a typo, perhaps?  M0rg4n (talk) 03:56, 3 March 2010 (UTC)
replies: text: Just gibberish added by an IP editor. Removed. Tim Vickers (talk) 23:10, 3 March 2010 (UTC)
thread_title:  mandoflorpes 

message: Sizes of the various membrane elements are missing. Please add.  —Preceding unsigned comment added by 199.203.95.161 (talk) 15:04, 13 March 2010 (UTC)
thread_title:  sizes of elements are missing 

message: under the section "in simpler terms" talking about the lipid bilayer, it is written that the tails are hydrophilic and the heads are hydrophobic. this is the opposite of the truth and should be changed. it is even written elsewhere on the article that the tails are hydrophobic and the heads are hydrophilic
96.248.222.240 (talk) 02:36, 24 January 2011 (UTC)
replies: text: Done Stickee (talk) 06:02, 24 January 2011 (UTC)
thread_title:  Edit request from 96.248.222.240, 24 January 2011 

message: Plasma membrane is a redirect to this article, and is used later in it - but there isnt any definition - synonyms? Christian75 20:11, 17 July 2011 (UTC)
replies: text: This article is somewhat confusing - cell membranes actually include internal membranes. Plasma membrane is the outer membrane and is generally different (contains glycolipids and glycoproteins on the outer side) than many of the inner membranes. This should be clarified.  — Preceding unsigned comment added by Membrane-biologist (talk • contribs) 02:51, 26 August 2012 (UTC)
thread_title:  cell membrane - plasma membrane - Synonyms? 

message: Please change 
===Fluid mosaic model===
According to the fluid mosaic model of 
to
===Fluid mosaic model===
According to the fluid mosaic model of 
as I created a page describing the fluid mosaic model.
Charnixon (talk) 04:50, 5 December 2014 (UTC)
thread_title:  Semi-protected edit request on 5 December 2014 

message: According to the fluid mosaic model of 
as I created a page describing the fluid mosaic model.
Charnixon (talk) 04:50, 5 December 2014 (UTC)
thread_title: Fluid mosaic model

message: 165.155.200.91 (talk) 16:56, 23 March 2016 (UTC)
replies: text: Not done; request incomprehensible. Pinkbeast (talk) 17:20, 23 March 2016 (UTC)
thread_title:  Semi-protected edit request on 23 March 2016 

message: Substituted at 11:07, 29 April 2016 (UTC)
thread_title: Assessment comment

message: This article was written well. All of the paragraphs flowed into each other and were easy to follow. Under the "function" heading, it was easy to understand the different types of transport through the membrane. I liked that it was broken down into four sections, and that each was described in detail. All of the information presented was relevant to cell membranes except the last part of the paragraph under “Cytoskeleton”. The last part was all about cilia and their function on the cell, which is not relevant to the main focus of the cytoskeleton. Also, there were some places in the article where terms were not defined. This made it hard to understand what the information was talking about. For instance, under the "function" heading, in the second paragraph it says "The membrane also maintains the cell potential" it would help if the cell potential was defined, and describe how the membrane maintains it. 
All of the citation links provided in the references worked properly. However, most of the paragraphs in the article did not have a citation. A lot of facts were presented without a reference link of any kind. It would make the information more credible if they were supported with references. Other than the suggestions above, the article was very informative. There were no opinions or biased statements made. Maggiehager (talk) 02:34, 1 October 2016 (UTC)
thread_title:  Cell Biology Article Editing  

message: Hello fellow Wikipedians,
I have just modified  on Cell membrane. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
*Added archive https://web.archive.org/web/20110924181859/http://www.etap.org:80/demo/biology1/instruction3tutor.html to http://www.etap.org/demo/biology1/instruction3tutor.html
When you have finished reviewing my changes, please set the checked parameter below to true or failed to let others know (documentation at ).
Cheers.—InternetArchiveBot (Report bug) 23:22, 17 November 2016 (UTC)
thread_title:  External links modified 

message: Hello fellow Wikipedians,
I have just modified 2 external links on Cell membrane. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
*Added archive https://web.archive.org/web/20050621082405/http://www.biochemweb.org/lipids_membranes.shtml to http://www.biochemweb.org/lipids_membranes.shtml
*Corrected formatting/usage for http://www.etap.org/demo/biology1/instruction3tutor.html
When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.
Cheers.—InternetArchiveBot (Report bug) 19:13, 1 August 2017 (UTC)
thread_title:  External links modified 

message: The article states that the oolemma is not the plasma membrane of the egg cell. Maybe this is an outdated meaning of the word. At least, the contrary seems to be the major meaning,
The 6th one references a book that is funny in that it uses the term (as do the books referenced above) for the plasmalemma but has a Glossary stating the other definition. Note that also WP articles use the term as (or explicitly state it as equivalent to) 'plasmalemma', e.g. Vitelline membrane.
I suggest changing Oolemma from a redirection page to a disambiguation page linking this page and maybe ZP as per this dictionary. --Rainald62 (talk) 17:07, 7 May 2018 (UTC)
thread_title:  Oolemma 

message: Smart person's ing (talk) 07:56, 2 August 2018 (UTC)
replies: text: Not done: it's not clear what changes you want to be made. Please mention the specific changes in a "change X to Y" format and provide a reliable source if appropriate. Danski454 (talk) 10:42, 2 August 2018 (UTC)
thread_title:  Semi-protected edit request on 2 August 2018 

message: At the start of the History section, the phrase “Hooke misled the cell membrane theory ...” is grammatically incorrect. People get misled, not theories. I’m not sure what the intent was, but I’m guessing it’s something like Hook made an error in his version of (or contribution to) the theory. Or maybe it was that Hook misunderstood or misinterpreted someone else’s version of (or contribution to) the theory. Regardless, it needs fixed. I’d do it but: a) I, a non expert, would need to go figure out what the correct meaning is, whereas one of y’all bio types will probably know that already, and b) the page is edit locked. Oh, and when someone does fix it, you’ll probably want to drop the definite article (the word “the”) as well. That is, it should probably be just “cell membrane theory” rather than “the cell membrane theory”. (Either that, or “cell membrane theory” would need to be in title case — “Cell Membrane Theory”, But I don’t think that’s what we’re looking for. Again, I’d defer to the bio people.) 2600:387:A:15:0:0:0:C4 (talk) 13:39, 6 August 2018 (UTC)
thread_title:  Hook misled a theory? 

message: Mingdao107 (talk) 08:55, 30 September 2018 (UTC)
replies: text: Not done: it's not clear what changes you want to be made. Please mention the specific changes in a "change X to Y" format and provide a reliable source if appropriate. Sir Joseph (talk) 14:19, 30 September 2018 (UTC)
thread_title:  Semi-protected edit request on 30 September 2018 

message: 2604:2000:1201:50D:1DE:D142:6A1B:8DDC (talk) 21:16, 27 February 2019 (UTC)
replies: text: Not done: it's not clear what changes you want to be made. Please mention the specific changes in a "change X to Y" format and provide a reliable source if appropriate. NiciVampireHeart 21:52, 27 February 2019 (UTC)
thread_title:  Semi-protected edit request on 27 February 2019 ; 

message: Lipids
Examples of the major membrane phospholipids and glycolipids: phosphatidylcholine (PtdCho), phosphatidylethanolamine (PtdEtn), phosphatidylinositol (PtdIns), phosphatidylserine (PtdSer).
The cell membrane consists of three classes of amphipathic lipids: phospholipids, glycolipids, and sterols. The amount of each depends upon the type of cell, but in the majority of cases phospholipids are the most abundant, often contributing for over 50% of all lipids in plasma membranes.[21][22] Glycolipids only account for a minute amount of about 2% and sterols make up the rest. In RBC studies, 30% of the plasma membrane is lipid. However, for the majority of eukaryotic cells, the composition of plasma membranes is about half lipids and half proteins by weight.
Change "for a minute" into "for a minimum" because the word minute seems out of place. PaulvanDoorenmalen (talk) 16:47, 9 September 2019 (UTC)
replies: text: .  It's a bit awkward, but see wikt:minute#Adjective.  Changing it would change the meaning, possibly inappropriately.  –Deacon Vorbis (carbon • videos) 01:43, 10 September 2019 (UTC)
thread_title:  Semi-protected edit request on 9 September 2019 

message: Variations
The cell membrane has different lipid and protein compositions in distinct types of cells and may have therefore specific names for certain cell types.
Sarcolemma in myocytes: “Sarcolemma” is the name given to the cell membrane of myocytes (also known as muscle cells).[43] Although the sarcolemma is similar to other cell membranes, it has other functions that set it apart. For instance, the sarcolemma transmits synaptic signals, helps generate action potentials, and is very involved in muscle contractions.[44] Unlike other cell membranes, the sarcolemma makes up small channels called “t-tubules” that pass through the entirety of muscle cells. It has also been found that the average sarcolemma is 10 m thick as opposed to the 4 m thickness of a general cell membrane.[45][43]
Oolemma is the cell membrane in oocytes: The oolemma of oocytes, (immature egg cells) are not consistent with a lipid bilayer as they lack a bilayer and do not consist of lipids.[46] Rather, the structure has an inner layer, the fertilization envelope, and the exterior is made up of the vitelline layer, which is made up of glycoproteins; however, channels and proteins are still present for their functions in the membrane.
Axolemma: The specialized plasma membrane on the axons of nerve cells that is responsible for the generation of the action potential. It consists of a granular, densely packed lipid bilayer that works closely with the cytoskeleton components spectrin and actin. These cytoskeleton components are able to bind to and interact with transmembrane proteins in the axolemma.[47][48]
Replace "that pass through the entirety of muscle cells. It has also been found that the average sarcolemma is 10 m thick as opposed to the 4 m thickness of a general cell membrane."
 into
"that pass through the entirety of muscle cells. It has also been found that the average sarcolemma is 10 nm thick as opposed to the 4 nm thickness of a general cell membrane."
Cause nanometer is a far more believable scale then the opposed meter. PaulvanDoorenmalen (talk) 17:57, 9 September 2019 (UTC)
replies: text: Done https://ui.adsabs.harvard.edu/abs/1966Natur.211..534R/abstract states "the sarcolemma is regarded as a semi-permeable unit membrane about 100 Å thick". Based on an Angstrom being 0.1nm, that would make it 10 nm. NiciVampireHeart 23:25, 12 September 2019 (UTC)
thread_title:  Semi-protected edit request on 9 September 2019 

message: In the subsection headed 'Lipid bilayer' it says  'Flippases and scramblases concentrate phosphatidyl serine, which carries a negative charge, on the inner membrane.' Shouldn't this be 'on the inner lipid layer' to distinguish lipid layers from the complete membrane?
Strayan (talk) 01:31, 18 October 2019 (UTC)
thread_title:  Use of 'inner membrane' to mean inner lipid layer 

message: I think students would like to know the membranes or organelles may differ structurally from the cell membrane. Specifically the tonoplast. I was surprised that it is not even mentioned in the article. Numerous high school biology teachers seem to use this term; perhaps it's outdated and not used at higher academic and research levels? Strayan (talk) 03:48, 28 April 2020 (UTC)
thread_title:  Organelle membranes 

message: This whole article is badly written and desperately needs to be made more readable.  — Preceding unsigned comment added by 86.157.234.81 (talk) 21:23, 14 April 2021 (UTC)
thread_title:  Badly written article 

message: What is plasma membrane 2409:4042:259E:4BF1:22A0:1566:97D7:C043 (talk) 11:15, 23 April 2022 (UTC)
thread_title:  Biology 

message: Protein lipid carbohydrates 205.254.163.108 (talk) 09:56, 28 May 2022 (UTC)
thread_title:  Cell membrane component 

message: 3 modes of movement substances 41.114.244.20 (talk) 16:27, 1 June 2022 (UTC)
thread_title:  Life Science 

message: Isn't any wall between the bilayer Jaffarnaik (talk) 11:57, 20 July 2022 (UTC)
thread_title:  Cell membrane 

message: Plasma membrane have some identity cards.
Such as it has glycolipids and glycoproteins which act as receptors..... 103.131.214.245 (talk) 02:24, 7 October 2022 (UTC)
thread_title:  Plasma membrane 

message: Voice 2406:7400:56:7926:F83F:FEB6:9C01:434E (talk) 23:17, 19 February 2023 (UTC)
thread_title:  Cell membrane 

message: I'm not an expert on this topic and just heard about oolemmas for the very first time, but if I'm not mistaken the mention of the oolema in the "variations" section in the article doesn't make much sense (which is 1/3 of the topics in the variations section). The introductory sentence makes it seem like this is about variations of a cell membrane. However the oolemma is probably a structure ON TOP of a cell membrane, right? It is more like a ECM or cell wall type of structure, and not a variation of of a cell membrane. ScienceEel (talk) 22:33, 11 August 2023 (UTC)
thread_title:  Mention of oolemma seems wrong