Talk:Infliximab

message: http://www.reuters.com/newsArticle.jhtml?type=healthNews&storyID=6059613
This link is not good, it is in the article where the FDA gives a warning. — Preceding unsigned comment added by 192.132.64.2 (talk) 00:59, 22 June 2005 (UTC)
thread_title: This link is not good

message: I see no reason to not merge the pages.  --zandperl 02:22, 10 January 2006 (UTC)
thread_title:  Page merging 

message: I note that the indications are American -- they differ in other countries Barry Zuckerkorn 19:36, 24 January 2006 (UTC)
thread_title:  Indications 

message: I miss the mention of Infliximab for the treatment of chronic uveitis and sarcoidosis. On patients websites for these diseases in both Europe and the United States you will find plenty of people following a succesfull long term treatment with Infliximab. Currently all medical insurance plans in the U.S. cover Infliximab for the treatment of sarcoidosis.  There has also been a double blind randomised placebo controlled study on 137 sarcoidosis patients being treated with Infliximab. The study suggests a limited improvement in short term lung sarcoidosis patients and a significant improvement in patients with chronic refractory sarcoidosis. Types of extra pulmonary sarcoidosis like neurosarcoidosis seem to show the best reaction to the treatment.
For this comment I refer to the AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE VOL 174 2006 
for infliximab and uveitis http://ard.bmj.com/cgi/content/abstract/66/4/548
patient websites: 
groups.msn.com/sarcoidbuddies
http://groups.msn.com/BesnierBoeckSarcoidose  —Preceding unsigned comment added by 217.136.229.100 (talk) 15:02, 30 May 2008 (UTC)
thread_title: Also used for chronic uveitis and sarcoidosis

message: Crohn's does not represent the product of anti-self immunity. — Preceding unsigned comment added by 83.70.249.174 (talk) 01:51, 25 October 2006 (UTC)
thread_title:  Should Crohn's be considered an autoimmune condition 

message: I miss the explicit warning for the high risk of reactivation of latent tuberculosis infection (LTBI), which is 5-10% in persons with LTBI on infliximab. Since the classical granuloma formation is absent the reactivation tuberculosis manifests itself in a severe disseminated form. Before startin infliximab screening for LTBI is needed. Persons from countries with a high tuberculosis prevalence need special attention.
Sytze Keizer 
Tuberculosis Chest Physician, 
Amsterdam —The preceding unsigned comment was added by 212.123.200.82 (talk) 08:37, 23 March 2007 (UTC)
replies: text: Absoluut. De vraag is of een Mantouxtest voldoende is, of dat er gescreend moet worden met interferon of ELISPOT. JFW | T@lk 14:42, 1 April 2007 (UTC)
replies: text:  translation please - Rod57 (talk) 13:41, 9 February 2016 (UTC)

text: Neither this article or Tuberculosis seem to describe this adequately - where should it go ? - Rod57 (talk) 13:41, 9 February 2016 (UTC)
thread_title:  high risk of tuberculosis 

message: I was doing some research on the deceptive marketing practices of a different drug company and kept coming up with mentions of some pretty astounding deceptions used to market Remicade and/or get it to be a covered expense.  I have no opinion on the drug one way or another but if you google the name and the wrod deceptive, you'll see what c omes up.  These are well decumented events.  I don't want to step in add  a section of other frequent contributors feel it isn't warrented.  I was merely surprised that no mention was made in the article of the C.A.R.E. Scam and the price-fixing scandal.LiPollis 10:52, 26 June 2007 (UTC)
thread_title: Should we have a section for controversies?

message: Improvement in many conditions is spectacular. In IBD,  suggests the HRQOL is persistently improved. JFW | T@lk 14:42, 1 April 2007 (UTC)
thread_title:  IBS QOL 

message: Studies(published by the AMA) show that patients taking he rheumatoid arthritis drugs Remicade® (infliximab) or Humira® (adalimumab)have, on average, a three fold increased risk of developing cancer
http://cancer.nchmd.org/news.aspx?id=36984
the study mentioned is:
Bongartz T, Sutton AJ, Sweeting MJ, et al. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serous infections and malignancies. Journal of the American Medical Association. 2006;295:2275-2285. —The preceding unsigned comment was added by 71.230.43.224 (talk) 04:17, 2 May 2007 (UTC)
thread_title:  Cancer risk 

message: I put the word out to the original contributor to repair the broken refs, if possible.  See User:Statesman 88#ACCENT1.  MaxEnt (talk) 03:26, 5 December 2007 (UTC)
thread_title:  Broken refs 

message: Simponi, aka golimumab, was recently approved.  Ronabop (talk) 05:21, 26 April 2009 (UTC)
thread_title:  Golimumab not listed? 

message: hi. just a quick note to say having just read the article i found the mix of trade names and generic names (sometimes in the same sentence!) when discussing drugs quite confusing. i appreciate when discussing trial results it may be more appropriate to include the trade name of the particular brand used but when discussing modes of action, ie in the pharmocology section, should only generic names be used? anyway i dont kno if people agree and i wouldnt kno how to change the article myself anyway!  —Preceding unsigned comment added by 77.98.220.164 (talk) 15:01, 7 December 2009 (UTC)
thread_title: mix of trade names and generic names

message: Since I am waiting for approval to start a treatment using Infliximab, I thought I would suggest that Sarcoidosis be added to one of the conditions this medication is designated as a treatment for.  The NeuroSarcoidosis Wiki page does list it.  — Preceding unsigned comment added by 63.67.211.220 (talk) 15:10, 19 August 2011 (UTC)
thread_title:  Treatment For / Sarcoidosis 

message: Not being a biotech, /me still thinks it ain't an engineered protein, and should be categorized with mAb's only. 46.138.66.66 (talk) 13:31, 5 November 2011 (UTC)
thread_title:  Not an engineered protein 

message: As someone who has worked in the field of mAbs, it seems misleading to characterize this as both chimeric (see right box, and text), and humanized.
If the mAb is humanized (which has a very specific meaning in this context) it is no longer considered chimeric.  Since Infliximab has the "xi" it is, by definition, chimeric, not humanized.  Remove "humanized" from the description.  — Preceding unsigned comment added by Scott8586 (talk • contribs) 19:18, 16 April 2012 (UTC)
replies: text: Update: changed it myself.  — Preceding unsigned comment added by Scott8586 (talk • contribs) 19:25, 16 April 2012 (UTC)
thread_title:  Chimeric or Humanized, not both. 

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thread_title:  External links modified 

message: It's a mix of general discussion of TNF inhibitors and specifics about Infliximab. Could move most to a section Mode of action - which can have a brief section comparing with other TNF inhibitors ? - Rod57 (talk) 13:18, 9 February 2016 (UTC)
thread_title:  Can we subdivide Pharmacology section 

message: FDA Staff Gives Infliximab Biosimilar Rave Review may warrant a mention of biosimilars ? - Rod57 (talk) 13:31, 9 February 2016 (UTC)
thread_title:  Remsima may become the second approved biosimilar in the U.S 

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thread_title:  External links modified 

message: What is the cure or reversal of this drug and symptoms in body??? 2601:346:4301:8F50:A031:FC35:7DC1:7075 (talk) 22:28, 31 December 2021 (UTC)
thread_title:  Reversal