Talk:Phosphorylation

message: A reaction diagram showing the biological phosphorylation reaction of commonly phosphorylated amino acids (i.e. tyrosine, serine, threonine) would be lovely.
Neuroschizl (talk) 18:53, 6 December 2013 (UTC)
thread_title: Add reaction

message: This page is more exhaustive than Protein phosphorylation and the information there should be incorporated here.--hroest 00:14, 11 January 2009 (UTC)
thread_title: Merger proposal

message: I can't help but think this Wikipedia page could really be expanded upon with the addition of several figures detailing some example pathways and mechanisms in which phosphorylation works. The section on "function" is pretty detailed, but the inclusion of pictures could really add to the material and help to clarify any issues that people may have. Would it be a good idea to add some basic pathways that phosphorylation occurs in? Maybe create a "general" template with simple names such as "ligands," "receptors," "proteins," and "phosphorylates"? Just a little advice that I think could make this page even better! MChapman5 (talk) 00:19, 4 February 2013 (UTC)
thread_title:  Pathway Additions? 

message: The article says that "Protein phosphorylation is one type of post-translational modification" which is not technically correct. See this for reference http://www.ncbi.nlm.nih.gov/pubmed/21868676 I have reproduced these results myself -  cotranslational phosphorylation is real! The truth is out there!  — Preceding unsigned comment added by 2001:4CA0:200:3:200:5EFE:8D54:4514 (talk) 21:05, 27 February 2013 (UTC)
thread_title:  Cotranslational phosphorylation? 

message: The Function section on this page is largely overlapping with the same section on the Protein phosphorylation page. I suggest to merge the section from this page into the latter. The section here should be shortened significantly.
I have moved several sections already over to Protein phosphorylation but have to take a break now. I suggest to retain this page as a general overview of phosphorylation and focus on proteins in the Protein phosphorylation page. Peteruetz (talk) 17:47, 4 November 2016 (UTC)
thread_title:  Merge Function section with corresponding section on Protein Phosphorylation page 

message: Somebody has written the inscrutable: "The liver’s crucial role in controlling blood sugar concentrations by breaking down glucose into carbon dioxide and glycogen is characterized by the negative delta G value, which indicates that this is a point of regulation with." With what? This is a vague, clumsy, confusing expression. Can someone competent please amend? Thanks. Trevor H. (UK) 17:00, 23 August 2018 (UTC)
thread_title:  Odd English? 

message: Maybe some of the older lit could be replaced by the updated info from a thematic issue of Chemical Reviews.
#Ahn, N., Introduction:  Protein Phosphorylation and Signaling. Chemical Reviews 2001, 101, 2207-2208.
#Newton, A. C., Protein Kinase C:  Structural and Spatial Regulation by Phosphorylation, Cofactors, and Macromolecular Interactions. Chemical Reviews 2001, 101, 2353-2364.
#Haskell, M. D.; Slack, J. K.; Parsons, J. T.; Parsons, S. J., c-Src Tyrosine Phosphorylation of Epidermal Growth Factor Receptor, P190 RhoGAP, and Focal Adhesion Kinase Regulates Diverse Cellular Processes. Chemical Reviews 2001, 101, 2425-2440.
#Saito, H., Histidine Phosphorylation and Two-Component Signaling in Eukaryotic Cells. Chemical Reviews 2001, 101, 2497-2510.
--Smokefoot (talk) 13:40, 18 February 2019 (UTC)
thread_title: Chem Rev

message: This first sentence currently reads as so:  
  
"In chemistry, phosphorylation (a phosphate group is added to a molecule) of a molecule is the attachment of a phosphoryl group. "  
  
The parenthesised part is obviously meant to be a breakdown of the word but there is no need as 1. the article already starts with a definition of the word anyway and 2. phosphate and phosphoryl, as far as I can tell, are not the same thing. So which is it? Is phosphorylation the addition of a phosphoryl group or a phosphate group? As a layperson I could see it as either, as the only chemical structure of a phosphorylated protein I have seen had a phosphate group, but if the connecting oxygen atom was already part of a hydroxyl group, for example, then maybe it's still just the addition of a phosphoryl group.
Anditres (talk) 03:41, 15 December 2020 (UTC)
thread_title:  Addition of phosphate or phosphoryl?