Talk:Adenosine diphosphate

message: The lead section is clear and is a nice summarized introduction to the article. The lead section could have some in-line citations embedded in the paragraph to improve quality. The article as a whole is neutral and flows nicely to where a user could easily find information within the article. The article does not contain any jargon but could benefit from creating a beginning sentence for each paragraph that better defines the topic for a non specialist user without being overly specific. Some of the references are PDF files to notes or some other media. My suggestion would be to find published journal articles that support the information in the paragraphs. An example would be the subsections of "Cellular Respiration", some of these references are PDF files to notes. The article could also improve with additional cited references but all other references correlate with the information given in the article. Another suggestion I have is to link the subsections of "Cellular Respiration" to other main article pages, so that the user can quickly go to another Wikipedia article that might have more detailed information. The images within the article could improve with more in depth explanations rather than a title for the image, for example, the "glycolysis overview" image could be confusing to most users, so a short explanation could help a user understand the process. My last suggestion for the article is to better define ADP's role in blood platlet activation. This section is a little confusing but important. The article overall is informative and not to specific with details, and with added information to its subsections, has the potential to move from a stub class. Autumn Zack-Taylor (talk) 17:55, 8 April 2013 (UTC)
replies: text: Thanks for the constructive assessment!  I absolutely agree with you as to the layout and need to be more clear in certain areas.PJCollettJHU (talk) 16:56, 25 April 2013 (UTC)
replies: text:  It looks like you guys are heading in the right direction with this article. I would suggest expanding the 'Blood platelet activation' section. The article would benefit so much with more referenced articles. Maybe you could add a section about possible diseases in relation to ADP? In all, I can see where your group added information and fixed some structural suggestions. Great job! Autumn Zack-Taylor (talk) 18:48, 29 April 2013 (UTC)
thread_title:  Comments from Azackta1 

message: My first impression of the article is that each particular section could be expanded upon with more information.  The lead section does follow the style guidelines, but is lacking inline citations to show validity of the information stated. The writing in the article is clear with understandable sentences. Each section flows into the next smoothly, so at the moment I don’t see any change required to sentences or paragraphs. However, in terms of gaps, a little more history on ADP and how it is made (i.e. the chemical reactions that combine the adenosine, ribose sugar and the phosphates) synthetically or biologically. Also, ADP is used for regulation in gylcolysis, citric acid cycle and oxydative phosphorylation. ADP is also found in signal transduction pathways;  what particular pathways  and what is the fate of ADP could be discussed. Another observation I made was that the article seemed to be “ATP” dominate in areas. The images posted are satisfactory and add decent visuals to the article sections. The blood platelet section is interesting. Are there any other topics that ADP is used like this? I don’t see any hint of plagiarism. With expansion of each section and more citations this will become a good article. Please let me know if you wish further clarification on any of my observations. DC DougCovert (talk) 16:09, 11 April 2013 (UTC)
replies: text: Thanks for the notes on our article, I appreciate the specifics!  We will definitely try to make the changes necessary to bringing up the quality of this article.  PJCollettJHU (talk) 17:00, 25 April 2013 (UTC)
thread_title:  Comments from DougCovert 

message: Hi ADP writers. The article is coming along, and thanks for adding more information to specific sections by using the “main article” link. Do you have any refs for the lead section and any more data pertaining to ADPs role in the platelet activation? Also, do you think it’s worthy to include more information regarding your last sentence about “RNA world hypothesis? DougCovert (talk) 17:59, 27 April 2013 (UTC)
replies: text: Hi DougCovert, Thanks for all of the input! I agree we need to add some additional references to the lead section, they will be incorporated shortly. I'm still uncertain if the RNA world hypothesis should be involved with this article or not. It was originally on placed in the stub but I'm uncertain if it should be placed the in final Draft; more to come on that as well. If you have any opinions please share. Jengel11 (talk) 12:09, 29 April 2013 (UTC)
replies: text: Hi there,It looks as though you've added in some refs to the lead and expanded the section as best you can. Good work, and thanks for considering my suggestions.DougCovert (talk) 02:20, 10 May 2013 (UTC)
thread_title:  Comments(#2)from DougCovert 

message: The lead section is very clear and concise and provides a good overview of the topic at hand. In addition, the lead does not contain any unnecessary wording that would confuse the readers. It has a continuous smooth flow from a neutral standpoint. One concern I have is the lack of citation that may support this section. The body does a good job covering several key components relating to the topic, however it seems to lack much depth in what is covered. Perhaps, you guys can work on expanding the subcategories a little more with a focus on emphasizing the subsections of cellular respiration. In addition, perhaps adding a section on the discovery or synthesis of ADP. As mention by Doug, this article seems more geared towards informing the readers about ATP and not ADP. Other than that, I think this article was put together very well. Great job. Binhtruong (talk) 03:04, 3 May 2013 (UTC)
replies: text: Thank you for the feedback BinhTruong. I added sources to the lead section as per your recommendations. Since the relationship with ATP is so closely associated to ADP It's been difficult to leave out important metabolic precesses' in respiration.Jengel11 (talk) 23:15, 9 May 2013 (UTC)
thread_title:  Comments from BinhTruong 

message: •	Removed “to” before the word located in the first paragraph of lead section.   Be careful with the wording of all sentences.  There are extraneous words such as “to” or “in” that do not belong.  Proofread prior to submitting the changes or additions.
•	Second paragraph of lead is repetitive with mentioning the phosphate groups being attached to the 5’ carbon of the ribose for AMP, ADP, and ATP.
•	Bioenergetics section is excellent and clearly explains the importance of energy released to do work from the breaking of phosphate bonds, and how cleavage of a phosphate group turning ATP into ADP aids in changing protein conformation.  Nice explanation on conversion of ADP back to ATP.
•	The second and last sentence under Glycolysis requires a citation.
•	The Oxidative phosphorylation subsection is mispelled as “oxydative”.  The explanation is clear and concise.  The last sentence requires a citation.
•	The second and last sentence under Mitochondrial ATP synthase complex requires citations.
•	The last portion of Blood platelet activation section (two bullet points and the sentence, “ADP in the blood…”) requires a citation.  The last sentence, “Single nucleotides…” does not seem to belong in this section.  Perhaps you can create a new but very short section to expand on nucleotides participating in the catalysis of organic reactions and just touch on the RNA world theory.
•	The images are great and relevant to the subsections discussed.  The image of the ATP synthase complex can be a bit more descriptive, but this may be more fitting for more novice readers.
•	Overall, the information in this article is in-depth, targeted, clear, concise, and well sourced.  Under Cellular respiration section, perhaps you can add a short background or explanation on the importance of cellular respiration and the general steps to provide a linearity and flow to all the proceeding subsections.
•	I know this is the last week, if you have time, can you add a small pathology section at the end of the types of mutations, let’s say, in enzymes or other proteins that are involved in cellular respiration and how this may disrupt all of these processes and result in various diseases or cell death, including additional journal article sources.
•	Hope this review helped. Cdunca12 15:54, 6 May 2013 (UTC)
replies: text: Thanks for the in depth review of our article Cdunca12. We've made some changes and added citations in response to your suggestions. Thanks for catching that very big misspelling "Oxydative" in the section title. Jengel11 (talk) 12:26, 10 May 2013 (UTC)
replies: text: No problem.  Great job on the article.  I know this was a lot of hard work for everyone.  Have a nice summer! Cdunca12 23:47, 10 May 2013 (UTC)
thread_title:  Comments from Cdunca12 

message: Substituted at 06:42, 29 April 2016 (UTC)
thread_title: Assessment comment

message: I would like to propose that we move the name to Adenosine pyrophosphate and rediredt Adenosine diphosphate to this "new" page. It is the correct IUPAC name for this molecule and should be the Wikipedia name as well.  — Preceding unsigned comment added by OrganicChem (talk • contribs) 02:59, 17 October 2016 (UTC)
thread_title:  Propose to move name to Adenosine pyrophosphate and rediredt Adenosine diphosphate.  

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