Talk:Centriole

message: In 1996 Dr Stuart Black and associates at the University of Chester discovered in a longitudinal study that children suffering stunted growth suffered from greatly reduced rates of cell mitosis, this also affected their ability to kill as quickly when compared to a control sample of those of average height. This is believed to be significant in showing that their centrioles had greater difficulty initiating the mitosis process due to the third spindle only consisting of two microtubules, instead of three.
I deleted this from the main article. There's no reference to the study in the article and i  couldn't find itin a quick pub med search. It's also not written well- what, the shorter children couldn't kill as quicly as their taller counterparts? I doubt that. Amutepiggy 23:08, 9 November 2006 (UTC)
thread_title:  Quote 

message: "A basal body (also called a basal granule or kinetosome) is an organelle formed from a centriole, and a short cylindrical array of microtubules. It is found at the base of a eukaryotic undulipodium (cilium or flagellum) and serves as a nucleation site for the growth of the axoneme microtubules. Centrioles, from which basal bodies are derived, act as anchoring sites for proteins that in turn anchor microtubules within centrosomes, one type of microtubule organizing center (MTOC). These microtubules provide structure and facilitate movement of vesicles and organelles within many eukaryotic cells. Basal bodies, however, are specifically the bases for cilia and flagella that extend out of the cell." -http://en.wikipedia.org/wiki/Basal_body
The problem is people mixing up the functions of centrosomes, centrioles and basal bodies. It is possible that the centriole's primary, or even only function, is in the formation of basal bodies in order to produce cilia and flagella. Centroiles evolved in single celled eukaryotes, probably aiding in motility - they form flagella. The mitotic spindle then evolved as a means of segregating centrioles and making sure each daughter cell had a flagellum. So instead of centrioles being important for the formation of the spindle, it is possible that the spindle is instead important for the segregation of centrioles. There are eukaryotes that lack cilia or flagella and it should be noted that these taxa also lack centrioles, yet are still perfectly capable of dividing and forming microtubles. These linages probably lost their centrioles as opposed to having never possessed them. Mitosis may have evolved primarily for the segregation of centrioles, but has since taken on other functions including cell division and chromosome segregation. Such critical functions would suggests why the loss of centrioles has not resulted in the loss of mitosis, in spite of it having originally evolved as a mechanisms for centriole segregation.  
What people seem to forget when they look at centrioles is how important cilia and flagella are to organisms that process them. If centrioles exist purely for their role in the formation of cilia and flagella, this would be more than enough to explain their existence and evolutionary conservation. Any single celled organism with defects in its flagella or cilia, or metazoan with defects in its primary cilia, motile cilia or flagella, will not survive. The functions of these organelles are critical and therefore the centriole is critical in all organisms that possess these structures.
—Preceding unsigned comment added by SlashRageQuit (talk • contribs) 04:48, 25 June 2010 (UTC)
thread_title:  What they do 

message: :"Proper orientation of cilia via centriole positioning toward the posterior of embryonic node cells is critical for establishing left–right asymmetry during mammalian development.(citation needed)"
Would think this is rather significant, either it can be referenced or should be deleted. --70.128.124.199 (talk) 01:33, 20 October 2010 (UTC)
thread_title:  Animal Development 

message: This article is very confusing when it comes to how the centrosomes/centrioles duplicate. Can someone clarify? —Kelvinsong (talk) 02:13, 10 December 2012 (UTC)
thread_title:  Do the mother centriole and daughter centriole separate and when? 

message: Substituted at 11:10, 29 April 2016 (UTC)
thread_title: Assessment comment

message: I believe the discussion of "mutant flies" in Centriole#Role in cell division could be better integrated with the rest of the paragraph. It seems to be a bit out-of-place. Somerandomuser (talk) 20:35, 12 May 2017 (UTC)
thread_title:  Cell development and mutant flies 

message: I believe this article's main diagram adds unnecessary complexity through the use of numbered labels. Would it be a good idea to add the labels into the diagram? Somerandomuser (talk) 20:46, 12 May 2017 (UTC)
thread_title:  Main diagram simplification