lflage/wiki-talks huggingface dataset:
Talk:Thomas Collins (cardinal)

message: I changed the Cardinal's name from Thomas Christopher Collins to Thomas Christopher Cardinal Collins. This was then reverted back by another member soon after the change. This name change is appropriate as per protocol as to how Cardinals are referred to and the style within the Roman Catholic Church. This is evident on the Profile Page for Cardinal Collins in the Catholic Hierarchy. Link to Profile Page Here. Instead of just adding it back in again I have started this discussion to give those who may be opposed to this change to voice their reasons why. Should there be no discussion on this I will make the change again at a later date. Please leave your thoughts on this topic. Magnetawan (talk) 23:20, 23 February 2013 (UTC)
replies: text: In accordance with tradition, they sign by placing the title "Cardinal" (abbreviated Card.) after their personal name and before their surname as, for instance, "John Cardinal Doe". This is described and referenced in the Section on Title and Reference on the Wikipedia page for Cardinal. This further solidifies reason to make the change to his name in the first line of the page. Magnetawan (talk) 23:31, 23 February 2013 (UTC)
replies: text: Signatures are one thing, names by which people are referred to are another.  Pope Benedict XVI signs as Benedict Pope XVI (Benedictus PP XVI), but is referred to as Pope Benedict XVI. We shouldn't try to be "more Catholic than the Pope" and tell him he was wrong to use the form "Cardinal Paolo Sardi" here, "Cardinal Gianfranco Ravasi" here, "Cardinal Józef Glemp" here, and so on and so on, never once using the form "John Cardinal Doe".  Esoglou (talk) 08:24, 24 February 2013 (UTC)
thread_title: Adding "Cardinal" within Name
Talk:5α-Reductase

message: Does someone have a reference for inhibition of Inhibition of 5α-reductase "results .. and, perhaps, increased levels of estradiol."  I don't doubt it might, but I wonder if any direct research has been done. Can a person survive with a 5α-reductase deficiency, or is there some kind of conditional inhibition disorder? Jimw338 (talk) 12:02, 23 November 2012 (UTC)
replies: text: Yes, you do not need the enzyme to live --> pseudo-hermaphrodites Ramwithaxe (talk) 12:08, 5 December 2012 (UTC)
thread_title:  Reference for inhibition effect on estradiol? 

message: " impaired cognitive function, fatigue, hypoglycemia, impaired liver function, constipation, and depression, " didn't appeared in any of the studies I saw about Dutasteride or Finasteride. 
Many of those mentioned can have psychological reasons, including the erectile dysfunction part. Even my doctor didn't mentioned this when I got a prescription for Avodart(Dutasteride).
Sometimes "side effects" are mentioned in some studies even when they have no actual relation to the drug, one study even mentioned influenza infection as side effect for Dutasteride.
Side effects need to be mentioned only when it is proven that the drug actually cause this side effect or if it is a very known side effect of the drug.
--5.22.135.154 (talk) 19:32, 12 August 2020 (UTC)
thread_title:  Many of the mentioned "side effects" don't appear in many of the 5a-Reductase inhibitors(like Dutasteride) clinical trial on people 

message: There is reference that steroidal’s are irreversible. There should be clarification of what exactly this means. Surely someone on finasteride who takes the pill for a month will no exhibit side effects for the rest of their life… 2607:FEA8:2CC1:B700:6524:8E8:D619:C0C5 (talk) 20:30, 18 September 2022 (UTC)
thread_title:  Steroidals are irreversible?
Talk:Round the Clock (Darts)

message: The darts page really didn't go into the amount of depth that I would have liked (at the time of the creation of this article. I'll currently try to tone down the amount of info on the section of this game on the darts page and make a summary with a link instead, or something. Contact my talk page for any comments on this idea. I was also having a bit of writers block while trying to find words for some of the events in the game. Feel free to rewrite it to make it more understandable. --Kevin (TALK) 22:56, 16 February 2007 (UTC)
thread_title: Why new page?

message: I don't really fully understand the etiquette of categorization. At the time of this post, this article I categorized this article under Category:Pub games and Category:Darts. Should this article be under Category:Darts only? --Kevin (TALK) 17:36, 17 February 2007 (UTC)
thread_title: Categorization
Wikipedia talk:WikiProject Software/Free and open-source software task force

message: is here FYI. -- Yae4 (talk) 18:50, 13 June 2023 (UTC)
thread_title:  [[WP:RSN]] Discussion of a source related to FOSS topics 

message: Talk:Open-source software
Hi, I'm a paid student editor and I have recently made some changes to the open source software Wikipedia page. I would appreciate it if someone could look them over and give their thoughts. Thanks!
Policy1257 (talk) 16:01, 25 January 2024 (UTC)
thread_title:  Requesting review of my edits 

message: A request was made to merge Free software and Open-source software into Free and open-source software. Sink Cat (talk) 02:16, 18 May 2024 (UTC)
thread_title:  Notice of ongoing merge request 

message: Hi all!
recently Bluefish (software) was soft deleted. Since then I've tried to get the quality of the article in shape again. I was convinced that I did it right, but the submission was declined. After that I used the list of reliable sources to improve the references. Before I submit again I hope somebody with more experience can have a look and tell if it is good enough or give me some tips to get it right this time. Thanks for your help! BlauweVis (talk) 19:54, 3 June 2024 (UTC)
thread_title:  Requesting assistance to get [[Bluefish (software)]] in good shape
Talk:Abzyme

message: This section tells the reader nothing about abzymes generally, and may raise false hopes for a new HIV treatment.  Also the section was added by an anonymous editor who may be one of the researchers using Wikipedia to publicize his own work.  And, one of the references in the section is to a primary source.  HandsomeMrToad (talk) 03:02, 4 July 2016 (UTC)
thread_title: Suggest removing "Potential HIV treatment" section
Talk:Activation-induced cytidine deaminase

message: A suggested merge of content from AICDA has been implemented.  I have taken the liberty of moving the unified page from activation-induced (cytidine) deaminase because I don't see any parentheses in recent PubMed results.  I have immodestly taken the C rather than stub class from the ratings for WPMCB on the two talk pages. :) Wnt (talk) 14:15, 9 January 2015 (UTC)
thread_title: Merge
Talk:Transgene

message: This page on cisgenesis: says that a transgene may also be a  synthetic gene, but I can't figure out how to fit that into the wording of the introduction paragraph. 213.202.134.29 (talk) 17:17, 2 November 2009 (UTC)

message: This page might need disambiguation, since there is at least one company of the same name:   — Preceding unsigned comment added by 173.32.146.126 (talk) 00:56, 3 January 2012 (UTC)
thread_title: Untitled

message: I notice this page has a large amount of transgenic methods in animals but only briefly mentions plants. 
There should be another tab of 'current uses' talking about transgenic approaches in plants; especially economically important plants.  I suggest using golden rice, Flavr Savr tomato, and glyphosate resistant crops as examples.  
This page should make notice of recent advances biotechnology mainly including ZFPs, TALEN, CRISPR.  These molecular approaches have become increasingly useful in building transgenic organisms.  Currently this page is laid out in such a way that this material would probably fall in the 'history' section.  In the future, I recommend the addition of a 'Methods' tab in which transgenic approaches can be listed and described.
The controversy section should also contain a little blurb about the anti-GMO craze and maybe mention the non-GMO project as an example.
The addition of figure would also make this page more aesthetically appealing.  A figure depicting foreign DNA being inserted into another segment of DNA would probably be a nice addition.
Cb841011 (talk) 05:42, 22 October 2015 (UTC)
thread_title:  Transgene Page Editing 
Talk:Amar

message: I know it as a given name as well in the Arab world...e.g. in the Mahgreb...--Lechhansl 22:59, 16 February 2007 (UTC)
thread_title: Untitled

message: Undying Love - combining both latin and the sanskrit roots — Preceding unsigned comment added by 24.85.75.98 (talk) 23:09, 13 July 2007‎ (UCT)
It's a person or thing which will not be destroyed Zeuz amarnath (talk) 15:57, 1 February 2017 (UTC)
thread_title:  Meaning of Amar
Talk:Alanine aminopeptidase

message: 81.11.206.47 (talk) 21:12, 30 October 2016 (UTC)
thread_title: membrane=alias??

message: Hello, I found the article to be lacking in a few matters, like the association with leukemia and lymphoma can be expanded upon with appropriate references. Also, the content of the article is the same as the abstract of the article in reference 3. That can be represented in a different manner. I hope my comments will be helpful in improving this article. Thank you.Dishabhavsar (talk) 01:11, 29 January 2017 (UTC)
thread_title:  few comments
Talk:Glutamate dehydrogenase

message: * Oppose –  if glutamate dehydrogenase 1 were merged into this article, then glutamate dehydrogenase 2 would also need to be merged.  Including two large  templates in the same article that already includes three  templates would overwhelm the text.  Boghog (talk) 14:03, 11 October 2011 (UTC)
thread_title:  Merger proposal 

message: you have presented the ability of "Glutamate dehydrogenase" to catalyze the reverse direction in a little bit confusing way: as if you was showing mammals to have "exceptional" inability of a reverse catalysis, whereas I would prefer if you present the ability of lower organisms (prokaryotes and some plants) to catalyze "two directions" as something exceptional ...
in other words: it is more readily accepted that the enzyme catalyze only forward reaction.and having some species catalyzing two opposite reactions by the same enzyme is the weird thing.  — Preceding unsigned comment added by Yasir muhammed ali (talk • contribs) 11:47, 8 April 2016 (UTC)
thread_title:  Notice : the opposite expression prefered 

message: It seems this apply only to the isoenzyme concerned with urea cycle, not the iso enzyme of the nervous system (GLUD2) Which is concerned with recycling of glutamate neurotransmitter, and is reversible in action.  — Preceding unsigned comment added by Yasir muhammed ali (talk • contribs) 18:45, 10 April 2016 (UTC)
thread_title:  the irreversibility of glutamate DH in vertebrates:
Talk:Aminopeptidase

message: The text in this stub is plagiarized from "Aminopeptidases: structure and function," by Allen Taylor, in an article from The FASEB Journal 7.2 (1993), pages 290-298.  — Preceding unsigned comment added by 72.78.207.132 (talk) 18:28, 18 June 2020 (UTC)
replies: text: I've added quotations around the sentences taken from the abstract verbatim. They did have the reference citations behind them, but that is certainly no excuse for this to have happened. I am not knowledgeable enough about this subject to adequately summarize, so I have left a request for assessment with WIkiProject Science for the article as a whole, given the new content just added today, and informed them of the issue needing addressed. OIM20 (talk) 13:27, 20 March 2024 (UTC)
replies: text: Also not really qualified but I didn't read this talk page so I ended up summarizing it a bit. Hopefully there aren't any errors: I mostly just rephrased what was there. Unless there are more plagiarized parts that weren't quoted the problem should be fixed. In the future you can probably use the \{\{copyvio}} (don't keep the backslashes) template, or just delete the quoted text. Using the template usually someone responds pretty quickly. Mrfoogles (talk) 04:18, 8 April 2024 (UTC)
thread_title: Untitled

message: "Aminopeptidase" is an extraordinarily broad class of enzymes: "Any of several enzymes that catalyze the hydrolysis of the peptide bond of the terminal amino acid at the amino end of a polypeptide or protein", according to Wiktionary .  These are ubiquitous in the environment ( as a trivial example) and surely are not all zinc-dependent.
I'm not enough of a biochemist to even rewrite the stub, and I don't mean to speak ill of the good person who wrote it, but I think definition this stub presents is so narrow as to be basically wrong.
Asteen (talk) 20:59, 6 July 2008 (UTC)
thread_title: Scope is so narrow as to make this stub incorrect
Talk:Arginase

message: Arginase_1#Role in sexual response : If all aspects of NO biology were covered in this article, it would become unreadable. The specific applications of an enzyme should be discussed in the appropriate article Erection, if essential for the mechanism-of-action. Indeed, the discussion of NO there is like a footnote.
--Ossip Groth (talk) 14:51, 27 May 2013 (UTC)

message: In different places the article refers to the manganese ligands as water and hydroxyl. These are two different ligands being M-OH2 vs M-OH. There is a difference in chemistry between the two, especially in an enzyme active site where water can not be considered ubiquitous.  — Preceding unsigned comment added by 68.205.7.15 (talk) 04:09, 31 July 2017 (UTC)
thread_title:  Inconsistent Terminology
Talk:Aromatic L-amino acid decarboxylase

message: :The "map" shows dopa decarboxylase inside synaptic vesicles. However, as discussed here, dopa decarboxylase is located in the cytoplasmic compartment. --JWSchmidt (talk) 14:46, 7 April 2011 (UTC)
replies: text: Thanks for the correction and update. We updated the WikiPathways version, including references, and then updated the template used throughout Wikipedia. --AlexanderPico (talk) 04:17, 13 April 2011 (UTC)
thread_title:  Interactive pathway map 

message: What about the commonly used synonym AADC (l-amino acid decarboxylase)?  — Preceding unsigned comment added by 129.132.121.230 (talk) 14:41, 3 September 2012 (UTC)
thread_title:  Other names 

message: That information seems conspicuously absent. What atoms make up Aromatic L-amino acid decarboxylase?75.128.143.229 (talk) 20:37, 3 July 2014 (UTC)
replies: text: No, the domestic pig link was someone's poor attempt at humor. Thanks for pointing it out - I've removed it. Someone else will have to address your other technical questions though. Seppi333 (Insert 2¢ | Maintained) 22:27, 17 July 2014 (UTC)
thread_title:  What are the atoms that make it up? 

message: In case this page is renamed and  is still used in the article at the time, please edit Template:Phenylalanine biosynthesis and change the following 3 values inside the  templates as follows:
* change "Aromatic L-amino acid decarboxylase=" to "New pagename="  (without quotes)
Alternatively, just leave me a message on my talkpage and I'll do it. This change will retain the enzyme highlighting in the image for the article.  
Thanks  Seppi333 (Insert 2¢ | Maintained) 18:41, 31 October 2014 (UTC)
thread_title:  If this page is ever renamed
Talk:Aspartate carbamoyltransferase

message: The introduction (as well as the concept of an isolated ATCase in mammals) is totally wrong. Just click the UniProt or OMIM entries. It's a protein complex and the name is CAD protein. While further sections may well apply to the complex (I don't know about that), the introduction has to be rewritten for a three-enzyme complex. --Ayacop (talk) 09:03, 2 December 2008 (UTC)
replies: text: yeah, I should have specified it was prokaryotic. Hopefully its clear now. Someone else will have to write about eukaryotic version. Sasata (talk) 22:09, 4 December 2008 (UTC)
thread_title:  completely wrong
Talk:Henry Thomas Buckle

message: The most notorious slowpoke in England was Elijah “The Bristol Sloth” Williams: In the fourth game of his London match against Henry Thomas Buckle in 1851, Williams lavished such exquisite care on his 25th move that Buckle had time to write two chapters of his History of Civilization.
Buckle won. “The slowness of genius is hard to bear,” he said, “but the slowness of mediocrity is intolerable.”
From http://www.futilitycloset.com/2011/01/06/sitzfleisch/
--Rarian rakista (talk) 19:08, 6 January 2011 (UTC)
thread_title:  Story of his chess playing  

message: I am in the process of adding citations and expanding the article with section changes as needed.   Vejlefjord (talk) 22:46, 13 March 2016 (UTC)
thread_title: Ongoing editing

message: "At age nineteen, Buckle first gained distinction as a chess player. He was known as one of the best in the world. In matchplay he defeated Kieseritsky and Loewenthal."
Shouldn't it be said that Buckle was a great amateur chess player rather than one of the best chess players in the world? Joshua D. Muthi (talk) 16:57, 8 January 2022 (UTC)
replies: text: In the 19th century really all chess players were amateurs.  The idea of a chess professional didn't really exist, perhaps outside of some hustlers who made a living gambling.  Buckle was one of the world's best at that time. Quale (talk) 17:50, 8 January 2022 (UTC)
thread_title:  Buckle's Chess skills
Talk:Aspartic protease

message: There are several described superfamilies of aspartic proteases, each containing several families. The superfamilies are likely the results of independent, convergent evolution. (See MEROPS). The classification and evolution sections will need to be updated. T.Shafee(Evo﹠Evo)talk 23:55, 25 August 2015 (UTC)
replies: text: Classification updated. T.Shafee(Evo﹠Evo)talk 11:53, 6 September 2015 (UTC)

text: I've removed the following text which only describes one family. A broader, more inclusive evolution section would be a valuable addition. T.Shafee(Evo﹠Evo)talk 11:53, 6 September 2015 (UTC)
thread_title:  Classification and evolution out of date 

message: https://en.wikipedia.org/wiki/Aspartic_protease#/media/File:Aspartyl_protease_mechanism.png. In the image the O of the product is negatively charged, but this needs to be OH. 131.155.203.112
:Finally got around to making this correction (it fell off my todo list). Eventually I'll hopefully remake the image entirely in a cleaner style. T.Shafee(Evo&Evo)talk 13:13, 2 September 2017 (UTC)
thread_title:  The picture of the mechanism is wrong.
Talk:Chymosin

message: At present the article states "Chymosin is produced by gastric chief cells in infants..." and "The gene is found in humans (on chromosome 1), but it is not expressed."  These seem to be contradictory statements to me, is it that the gene is only expressed during infancy, or is something else going on here.  In any case the article would benefit from this being made more clear. --Keithonearth (talk) 17:49, 11 August 2011 (UTC)
replies: text: I agree with you. The article should be more clear. Active chymosin has not clearly found in humans, and babies don't digest milk using chymosin as the article wrongly states. However, there is a human non functional pseudogene related with prochymosine.--Miguelferig (talk) 18:37, 7 December 2012 (UTC)
replies: text: Miguelferig, could you correct the article. The citation for the fact seems to deal with sheep, not human infants. I don't have the background necessary to fix it myself. Thanks! --Glubbdrubb (talk) 11:45, 25 May 2013 (UTC)
replies: text: I've changed some sentences and added two new references.--Miguelferig (talk) 17:32, 25 May 2013 (UTC)
replies: text: Thanks! --Glubbdrubb (talk) 18:55, 27 May 2013 (UTC)
thread_title:  in humans gene not expressed? 
Talk:Nitrite reductase

message: Is it:
NO2  +  4 NAD(P)H  +  4 H+  ->    NH4  +  4 NAD(P)+  +  2 H20
????????
Come on guys this is fundamental.  should have been first bit of info in there
--129.67.116.3 (talk) 12:40, 26 May 2008 (UTC)
thread_title:  What Reaction does it catalyse?!
Talk:Beta-secretase 2

message: The first paragraph ends with "one of which is the protein encoded by this gene." - Which I think is referring to the Entrez gene from the eighth source but none of it is clear in the paragraph. It seems a lot of the main paragraph has been hastily spliced together from multiple sources and needs clarifying.  — Preceding unsigned comment added by 74.136.76.69 (talk) 16:04, 6 September 2018 (UTC)
thread_title: Untitled
Talk:Galactoside acetyltransferase

message: Why is the role of lacA still not known? 84.112.136.52 (talk) 21:37, 10 October 2013 (UTC)
thread_title:  Role 

message: The article should explain why this enzyme is needed for the metabolism of a bacterium. 84.112.136.52 (talk) 02:53, 19 November 2013 (UTC)
thread_title:  Why is it needed
Talk:Hepatocyte growth factor receptor

message: Kudos to primarily contributor(s)!!!!
:That would seem to be User:ZTebaykina --JWSchmidt (talk) 03:34, 24 June 2009 (UTC)
thread_title: Awesome article

message: The title is "C-Met", the article begins with "C-Met", but this term is not used elsewhere in the article. Can anybody clarify this? Palpalpalpal (talk) 09:33, 17 November 2010 (UTC)
thread_title:  c-Met vs. MET 
Talk:Canon XM2

message: I don't ever remember seeing a discussion about this. Who decided that the article should be called Canon XM2?
Google does turn up more results for "Canon XM2", but I'd like to hear the reasoning behind this change.
Am I right in assuming that the XM2 is a PAL camera, whereas the GL2 is NTSC? This should be noted in the article.
Also, what happened to the information about carrying over features from the Canon XL-1s? Is this disputed, or did it just get dropped during the merge?
Thanks.
-Fadookie Talk 23:08, 16 February 2007 (UTC)
thread_title:  Renaming of this article 

message: I was kind of getting tired of the picture that was on this page, and I just wanted to give a heads up that i would like to update the pictures on this page for GL2 with this photo I uploaded to Wikipedia. This is a picture that I took myself, and is of my own personal property. But it can be used for anything! Especially for this page, which i originally intended it for! :)
My Web Page 
Thank you, Mazakar (talk) 21:31, 25 November 2007 (UTC)
thread_title:  New Picture 

message: When the canon xm2 pal was made? 46.214.33.245 (talk) 16:26, 21 February 2022 (UTC)
thread_title:  Canon xm2 pal
Talk:C3-convertase

message: See Glomerulonephritis#Membranoproliferative.2Fmesangiocapillary_GN and Membranoproliferative_glomerulonephritis#Type_II. - Rod57 (talk) 14:35, 13 January 2013 (UTC)
thread_title:  Implicated in kidney disease 

message: C3 is located on chromosome 19 in humans (OMIM). The article says chromosome 6 and I think it is wrong.--Miguelferig (talk) 17:07, 17 May 2014 (UTC)
thread_title: Location on chromosome
Talk:CYP17A1

message: Is this article talking about the enzyme or the gene that encodes for it? — Preceding unsigned comment added by 107.194.88.198 (talk) 18:11, 17 September 2012 (UTC)
thread_title:  Enzyme vs Gene 

message: The inhibitor article is quite small now. Should we merge the articles https://en.wikipedia.org/wiki/CYP17A1 and https://en.wikipedia.org/wiki/CYP17A1_inhibitor ? --Maxim Masiutin (talk) 14:53, 15 July 2020 (UTC)
thread_title:  Merge the "inhibitor" article with the main one
Talk:CYP1A1

message: "Ultimate" needs elaboration in this sentence, especially since the resultant substance has no wiki entry: ...CYP1A1 catalyses this intermediate to form BP-7,8-dihydrodiol-9,10-epoxide, which is the ultimate carcinogen.
: After checking the wiki entry for (+)-Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide, I believe that the original editor was referring to the fact that this chemical is produced by the final (i.e. ultimate) step in the reaction. The meaning was distorted by importation. I've removed the offending adjective altogether. Aeffenberger (talk) 18:09, 14 January 2020 (UTC)
thread_title: Ultimate Carcinogen?