Talk:Physical dependence

message: I'm not sure that increasing tolerance is necessarily part of physical dependence. I think a person -can- be physically dependent on a drug (and will suffer physical withdrawl if it is suddenly stopped), without being caught in the vicious circle of increased tolerance leading to increasing dosage resulting in further tolerance. - Pacula 17:10, 31 October 2006 (UTC)
thread_title:  Increasing tolerance automatically part of physical dependence? 

message: Physical dependence  is a symptom of some addictions. The fact is this is an attempted to separate the dirty street addict who uses heroin from the well to do mothers of 2 who uses Oxycontin from a doctor with some uses of the word. The effort to make people who despise addicts but are ones themselves feel better that in some way they only have a physical need and otherwise they do not use for the same reason people who are black poor or city folk do . Physical dependence  does not mean there is no psychological need for drugs. Physical dependence and the withdrawal from such dependence is very, very psychological the head aches the sleeplessness certainly causes psychological effects . The idea that  with psychoactive drugs the physical dependence can be separated from the psychological effect is just well umm OK stupid. Maybe use heroin for a few year withdraw then go to rehab and get clean and try not to relapse when you can go down street that is a drive threw open air drug market. I think there is something about using and not and understanding such things and I know everyone will say no it is science not experience or feelings it is try it!!!!
N. Riley Friday November 18 2007 10:54PM
I enjoyed a particular reference to NSAID addiction. Commonly cited “accepted” societal addictions such as  nicotine or caffeine are usually not debated. This particular reference however describes “massive” NSAID addiction which is not commonly known.  Such drugs show no physical addiction or “rewarding” brain pathways but are in fact considered highly “abused”. Such use is the compulsion out of habit (hate to use the cliché) but not for pleasurable effects. Suppose one has a headache and takes as aspirin. The headache is persistent even after the aspirin is metabolized so another is consumed. Eventually this becomes a compulsion out of “fear” that the headache will return after the drug wears off or perhaps to avoid a rebound headache. Acetaminophen (or paracetamol for our overseas friends) is highly toxic and arguably taken in excessive amounts. There is in fact a difference between physical and physiological addiction although I wouldn’t debate the use of physical addiction as a cover in order to avoid the guilt or even to avoid addressing a physiological addition. 71.92.107.39 (talk) 08:46, 1 March 2008 (UTC)
replies: text: This section needs to be written on the whole, as it does not make a difference on a) How it developed? b) How is the person's medical conditions at the moment? The text should make it clear that there are several different definitions of the term in the scientific world. The substance of the text is, for example, not true at all, compared with DSM-IVDala11a (talk) 07:46, 21 May 2008 (UTC)
thread_title: Difference from Addiction

message: The sentence:
Treatment usually requires the initiation and then tapering of a medication that has a similar action in the brain but a longer half-life.
is incorrect, besides being uncited.  The most common drug for which withdrawl is treated is alcohol and, at present, only rarely is alcohol used during medically-supervised withdrawl.Desoto10 (talk) 21:53, 11 April 2008 (UTC)
thread_title: Treatment

message: Anticonvulsants, antipsychotics, and antidepressants have been wholesale declared to be causing physical dependence, which is generally unproven (except for benzos, which are included in the list separately anyway). Xasodfuih (talk) 01:06, 22 December 2008 (UTC)
replies: text: SNRI and SSRIs cause withdrawal on discontinuation.  But effexor is also know to cause addiction.  Check out:  As is Tianeptine: --Doc James (talk) 13:35, 22 December 2008 (UTC)
replies: text: I would agree with literature's approach.--Doc James (talk) 21:34, 22 December 2008 (UTC)
thread_title:  Disputing the inclusion of whole classes in the list 

message: There are many classes of drug that induce physical dependency and/or discontinuation syndromes that are not suitable for use as recreational drugs.  Most medications intended to regulate basic bodily functions cause a discontinuation syndrome if discontinued incorrectly, whether they are meant to regulate mood or blood pressure, but few people would argue that someone taking blood pressure medication as prescribed was an addict.  Perhaps more references to less-controversial drug categories would help make the distinction clearer?  Nightsmaiden (talk) 10:51, 30 July 2010 (UTC)
thread_title:  The Distinction from Addiction is not spurious 

message: I've just moved caffeine from the list of drugs that cause physical dependence to the following section on rebound effects. While the article cited in support of having caffeine in the list does use the term "physical dependence" in the title, it's clear from the abstract that the withdrawal symptoms being described are inconsistent with the definition of physical dependence earlier in the article, but are instead the more minor symptoms described in the section on rebound effects.Jbening (talk) 14:23, 18 September 2010 (UTC)
thread_title:  Caffeine 

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thread_title:  External links modified 

message: currently redirects to physical dependence. However, they are very distinct concepts. The former is a neurological mechanism which can explain the latter. I got here by following a link from the page about kindling. I was expecting a very different article when I clicked that link. Specifically, I was expecting an article which explained in detail how neurons adapted to their environmental conditions. Instead, I was redirected to a page about symptoms and treatment of the resulting clinical condition. What I expected and what I got were two completely different things at completely different levels of abstraction: neurological/neuroscientific and clinical, respectively. Matheus Afonso Martins Moreira (talk) 19:34, 2 June 2016 (UTC)
thread_title:  Neuroadaption should not redirect to this page