Talk:Nitration

message: This article seems to specific in only discussing the nitration of aromatic compounds.  Nitration can be performed on other molecules, such as alcohols.  For example, the nitroglycerin page describes its synthesis as the nitration of glycerin.--24.16.148.75 21:15, 10 July 2006 (UTC)
replies: text: Perhaps the Aromatic nitration section could be improved slightly by mentioning activating and de-activating ring substitutents wrt selectivity?GreatMizuti 13:00, 20 July 2006 (UTC)
replies: text: I looked at those pages and noticed something about them both, they're stubs! They lack detail, accuracy (sorta) and depth! I mean, surely you can't imply that that's anything near a comprehensive list of activating/deactivating groups epecially since inductive effects are easily translated across conjugated system, oh and the absence of diagrams. Those articles are going on to my to-do list! (I need some practise using ISIS draw)GreatMizuti 12:58, 22 July 2006 (UTC)
thread_title:  Too specific 

message: "Substituents such as other NO2 groups have an electron pair donor effect which deactivates the reaction"
Nitro groups are strong pi and sigma electron withdrawers. This sentence makes no sense at all. Donor should be replaced with withdrawer. Also one does not activate or deactivate a reaction, there is a mess up with the lingo too. You catalyze or retard a reaction. The author of this sentence should be familiar with the meaning of the latter word well enough.
::Really? Are you sure? Here I was thinking that the use of catalysis in this example was erroneous because nitrating nitro-benzene was not the same reaction as nitrating benzene and thus we talk about activation and deactivation. As to your point of withdrawing effect vs donor effect, yes, that was an error on my part however (mercy be I am not infallible), as is indicated by the rather tidy diagram on the afore mentioned, linked page I already knew that. Thanks. Feel free to insult me in your retort, god knows I could use a laugh. :) GreatMizuti 15:55, 23 August 2006 (UTC)
replies: text: These observations seem correct to me and I urge you to edit the article to reflect them. —Keenan Pepper 02:49, 23 August 2006 (UTC)
replies: text: The statement was that amino groups can be activating substituents, well, I've never had to do that particular reaction either theoretically or in practise but there seems to be [|evidence a plenty] that you sir, are in error in that the statement is not wrong but simply not as anal as you would like it to be (although I'll have to give the matter further thought, my current thinking is that your line of logic forms a protonated and therefore positively charged nitrogen which is energetically less preferable than the substitution products). I honestly didn't know about amine substituents so I looked it up both in my notes and in the relevant texts and of course other wikipedia articles and there's a concensus: Amine groups can be activating groups. In fact, most references suggest that amine groups are strong activating groups.GreatMizuti 15:55, 23 August 2006 (UTC)
thread_title:  full of errors 

message: The first scheme has an error in it.
I think the highest/top red arrow should be coming from the bond rather than going to the bond and ending at the oxygen. The way it looks now is suggesting it will form a double bond.  — Preceding unsigned comment added by 94.214.148.76 (talk) 15:41, 29 November 2011 (UTC)
thread_title:  Error in the reaction scheme 

message: So in the last step the h2o comes and picks up the h, i dont think this is what happens, its the o-oso3h that does to form h2so4 because h2so4 was a catalyst and can't be consummed...Philoleb (talk) 21:30, 11 December 2011 (UTC)
thread_title:  Last step 

message: Is there enough research available to warrant a section devoted to the methods of nitration other than nitric acid/sulphuric acid mixtures?
Nitric acid/phosphoric acid mixtures look promising. There are also a few articles on nitrate salt/phosphoric acid mixtures.
http://jcsp.org.pk/index.php/jcsp/article/viewFile/1924/1357
http://pubs.acs.org/doi/abs/10.1021/ac60142a031
http://pubs.acs.org/doi/abs/10.1021/jo01034a063
http://www.springerlink.com/content/l736226872157485/
--SlapChopVincent (talk) 00:46, 4 June 2012 (UTC)
thread_title:  Alternative Methods of Nitration