lflage/wiki-talks huggingface dataset:
Talk:Jimmy (The Colbert Report)

message: I tagged this article. No need to have an increddibly short article on a person who has no great assertion of notability. --Tainter 01:45, 16 February 2007 (UTC)
replies: text: I agree, I've merged what little there was to The Colbert Report#Recurring characters --Lox (t,c) 22:34, 8 January 2008 (UTC)
Talk:Hemoglobin A2

message: — Assignment last updated by KD2023 (talk) 02:54, 21 November 2023 (UTC)
thread_title: Wiki Education assignment: Biochemistry I
Talk:Hemoglobin C

message: Hello everyone...I'm a bit exhausted at the moment, but it seems that the Symptoms topic's first line is a bit redundant. Not sure if the "mild to moderate enlargement of the spleen" and "splenomegaly" were meant to be listed as two things but to me they're saying almost the same thing. I didn't want to make the deletion since I didn't want to step on toes.---- Paul K. | MechE | MSY-2 | Chemist | Let's talk 17:39, 26 September 2019 (UTC)
thread_title:  Symptoms..
Talk:Hepatocyte growth factor

message: Like many articles on scientific subjects, this one seems solely directed at scientists. I came here to find out what hepatocyte growth factor is. I still have no idea. Is it possible that we could have a drive to edit this kind of article so that a lay reader can understand it? Such articles would be much more useful to most students, and to me. Sylvia A (talk) 20:06, 11 May 2011 (UTC)
thread_title: Untitled
Talk:Hepoxilin

message: The use of "hormone" is usually restricted to protein mediators.  Since this is a lipid, suggest changing this to "signaling molecule". JustAnotherKinase (talk) 08:03, 22 August 2010 (UTC)
thread_title: Hormone

message: Could someone please add some information about the link between hepoxillins and psoriasis?   --74.179.120.207 (talk) 17:04, 23 March 2011 (UTC)
thread_title:  hepoxillins and psoriasis 
Talk:Histone octamer

message: You guys have come a long way! This is a big improvement from where you were at the time of my first review. I really like have you've broadened the lead to make it more of a high-level overview. One suggestion I'd make is to follow the lead with the paragraph about "The Histone Octamer in the Nucleosome". I think it's easier on readers to take them through incrementally more detailed levels. Talking about the role of the histone octamer in the nucleosome would seem to me to be the next logical step. Second, I'm sure you know this already, but this subject cries out for some good illustrations. I'm thinking of something like the two-sided disc illustrations in our text. If you can't find anything good in the public domain, let me know and I have some good graphics art contacts (my son) who could whip up something for free. Third suggestion, it would be great to cite a very general reference the reader could use to get more "big picture" information. One I found is -
Alan P. Wolffe, Dmitry Guschin, Review: Chromatin Structural Features and Targets That Regulate Transcription, Journal of Structural Biology, Volume 129, Issues 2–3, April 2000, Pages 102-122, ISSN 1047-8477, http://dx.doi.org/10.1006/jsbi.2000.4217.
(http://www.sciencedirect.com/science/article/pii/S1047847700942175)
In the "History of Research" section, it strikes me as strange to talk immediately about post-translational modifications of histones when the subject is the histone octamer itself. How did scientists come to realize an octamer was involved? Also, you may plan to cover it later, but how does the octamer form? How long does it last? What happens to it during replication? These are some other good questions to consider answering.
Finally, there are still several awkward sentences. For example, in the lead you say "either in vivo...". I would expect that to be followed by "in vitro" later. The only "or" to follow the "either" is "without DNA". There are several other sentences with minor grammatical errors.
Hope that all helps. Don Brown (talk) 22:55, 18 November 2013 (UTC)
replies: text: I would still recommend a more conceptual illustration of the histone octamer - the type we have in our text that shows the octamer as a two-sided disk. I think an illustration of this sort would help the reader get the big picture more quickly. Don Brown (talk) 19:34, 2 December 2013 (UTC)
thread_title:   Second Review 
Talk:N-Acyl homoserine lactone

message: I edited this page a lot and attempted to improve flow, description, cross linking and referencing. It still needs A LOT of work. It could really shape up to be a good article with some assistance. I need citations for the bioluminesence stuff, maybe add biosensor related stuff from the Kumari et al. article. Also redirects really need to be fixed for AHL, acylated homoserine lactones, Homeserine lactones and N-Acyl Homeserine lactones (all should point at this page and I have no clue how to fix it). PedroDaGr8 (talk) 17:43, 31 October 2008 (UTC)
replies: text: Good job PedroDaGr8. I am going to add the lactone category as well --kupirijo (talk) 19:05, 20 November 2008 (UTC)
thread_title: Expansion

message: — Assignment last updated by Symbiologist (talk) 12:40, 6 October 2022 (UTC)
thread_title: Wiki Education assignment: Introduction to Chemical Ecology
Talk:Hopanoids

message: some broken grammar here... dunno what to do about it, dunno how to flag it
ill fix it later if nobody else has
24.108.206.194 04:30, 17 September 2007 (UTC)
thread_title:  Clean up 

message: The article already mentions this, which is nice; but the structure is not quite similar, e. g. hopanoids have
an additional ring. Perhaps even more differences. Would it be possible to expand the article a little bit in
order to accentuate these differences more, in the wiki-article as-is? I unfortunately do not have sufficient
knowledge to reshape that article in a meaningful manner. (I only just today read that hopanoids are similar
to cholesterol, for instance.) 2A02:8388:1604:CA80:F462:6A60:DEA:83A0 (talk) 14:21, 11 November 2018 (UTC)
thread_title:  Structural similarity to cholesterol
Talk:Hydroxymethylbilane

message: Bilane is defined as the unsubstituted linear tetrapyrrole with methylene bridges, or the whole class of compounds derived from this single compound by substitution of non-N hydrogens.Then, for consistency, "hydroxymethylbilane" (HMB) should be defined as the parent bilane with a single substitution of a terminal H by a hydroxymethyl; or the whole class of H-substituted derivatives thereof.But then preuroporphyrinogen (call it PUPG) is not the same thing as hydroxymethylbilane, in either sense; it is just one specific element of that class.  The use of both as synonymous is understandable in biochemistry, because PUPG seems to be the only HMB derivative that occurs in humans and some (most) other living beings.  However, now that chemists are playing with artificial porphyrins, that identity does not seem to be justified -- at least for chemists.Thus I propose to split off the information about PUPG as a separate article, and turn this one into an article on the parent compound and on the whole class.  In the head of this article, it will be noted that, in biochemistry, HMB usually means PUPG.  Any objections?--Jorge Stolfi (talk) 04:48, 10 March 2019 (UTC)
thread_title:  Split off preuroporphyrinogen from this article?
Talk:Calcium release activated channel

message: The ICRAC page could be moved to Calcium Release Activated Channels (CRAC). The calcium channel page lists store-operated channels (SOC). It is now reported that SOC is structurally related to CRAC, so the ICRAC and SOC channels pages could be merged into one Wikipedia article. --IONTRANSP (talk) 00:09, 1 September 2011 (UTC)
thread_title: Page Move

message: I moved this page from its capitalized and plural form. However, you may want to decide whether a hyphen should be used in the name, such as "calcium-release activated channel". Also, there are other names to consider, check what links to the article for variations of the current name as well as different names, such as "Store Operator Calcium Entry". Finally, non-capitalized versions of the capitalized redirects to this article should be created. -- Kjkolb (talk) 23:35, 6 April 2014 (UTC)
thread_title:  What should the article's name be?
Talk:Social complexity

message: I am wondering if there is any research on complex structures, in other words, the group version of self-construct, which is also sometimes 
concept within the self. or self-system:
*self-concept
*self-esteem
*self-efficacy
*self-agency
*experience processing (the bridge between the environment (which includes group) and self (concept).
I imagine this would work by just replacing self with group and looking for the relationship, which is interrelationship.  This may overlay object-oriented structure in terms of the environment, group, scope, and depth.--John Bessa (talk) 14:04, 31 May 2011 (UTC)
thread_title: Group-concept

message: Replacing this entire article with an early version of the edit to merge this topic with the article Sociology and complexity science. There are only brief statements in some sections, which are marked as stubs.  Since I'm a newbie here, I'd appreciate any comments, but particularly stylistic comments.Meclee (talk) 01:20, 6 November 2011 (UTC)
thread_title:  Article merger 

message: I have raised this article to "B" class.  If anyone disagrees with this rating, please point out possible improvements or edit to add information.  Ready to remove merge tags and redirect the Sociology and complexity science article to this article.  Thanks for comments! Meclee (talk) 23:53, 30 November 2011 (UTC)
thread_title: Re-Rating

message: <Sociology and Complexity Science> would probably be a better title.  The article seems to be about the study of social complexity.  It is NOT a description of <social complexity> (that article would be either very big or woefully inadequate). Given the amount of effort that someone made to merge two overlapping articles in a very interesting area, it is very surprising (to me, at least) that little thought was given to  the title.  "The scientific study of social complexity" seems a valid alternative; also "Sociology and Modelling Complexity".  Interested to hear other comments, but I repeat: the article is about the study of social complexity, whereas the title suggests it is ABOUT social complexity.  If I was Craig RH, I would only give the title 1 out of 10.    86.17.152.168 (talk) 18:10, 14 December 2014 (UTC)
thread_title:  Title is not very helpful 
Template talk:A-League Men stadiums

message: Regarding the changes made on 14/15 February to this and related stadium articles - the template is designed to be used with other templates as described in the comments on the main template page and at Wikipedia:WikiProject Football/Templates.  I don't think it is necessary to make a 3 line high template collapsible. -- Chuq 02:01, 16 February 2007 (UTC)
replies: text: when this template is used on stadium articles with multiple other templates i believe it is. i see the point in using this form of template on purely soccer related articles, but it just bloats the stadium articles. --Dan027 02:20, 16 February 2007 (UTC)
replies: text: Hmm I see what you mean there, maybe it should be renamed so it isn't an "AUS fb" template (all "AUS fb" templates use the same format - see Special:Allpages/Template:AUS fb - and are designed to go within the  and  tags).  I still don't think the "show/hide" is needed on such small templates however - only a couple of lines long. -- Chuq 01:40, 19 February 2007 (UTC)
thread_title: Template

message: I changed the main heading (A-League stadiums) back so that it links to the main article about the current/former/occasional use stadiums rather then the main A-League article, i think that is a much more appropriate place for it to connect to. --Dan027 (talk) 06:50, 17 February 2013 (UTC)
thread_title: Link in main heading
Talk:Inducer

message: The first sentence "an inducer is a molecule that starts gene expression" seems a little bit of vague to me. Because Gene expression is a broad process that includes transcription, translation, etc. For example,you said once the Allolactose binds to the lac repressor the transcription starts. You also mentioned that the increase of gene expression. Moreover, the start of transcription also needs lots of other factors like promoters. So I would say, rather than "start the gene expression", "regulate the level or time of gene expression" seems better. JiyaoZ (talk) 01:12, 9 February 2015 (UTC)
thread_title:  Some aspects could be improved
Talk:Mitchell's hopping mouse

message: Hello, the good latin name is  Notomys mitchellii  (with two i), you should correct it and actualise interwiki links. --Salixen 16:10, 21 May 2007 (UTC)
replies: text: Someone's fixed it. Equinox ◑ 02:29, 9 July 2017 (UTC)
thread_title:  Wrong latin name 

message: Equinox ◑ 02:29, 9 July 2017 (UTC)
thread_title:  Who is Mitchell?
Talk:Inosinic acid

message: Is it not factual that glutamine donates an NH3 group to FGAR to further aminate the molecule?
Chemotron (talk) 03:11, 5 March 2019 (UTC)
replies: text: Well, not exactly. It donates an NH group, or rather, it swaps an NH for an O. And the result is not an amine but an amidine. I have modified the article to be more accurate on this point. Eric Kvaalen (talk) 14:30, 22 May 2020 (UTC)
thread_title: Addition of ammonia?
Talk:Inositol pentakisphosphate

message: Why do you a-holes keep removing the important anti-cancer aspects of this substance every time it goes in here?  This is a prime example of why Wikipedia is non-authoritative and constantly incomplete.
Wikipedia will soon crash and burn due to its own lack of integrity.
--
I agree with the above, there is a mountain of evidence and a University College London study that belongs here.  IP was found to destroy tumors more effectively than the leading chemotherapy drug but with ZERO TOXICITY.  That is fairly remarkable, and surely warrants mention on Wikipedia.  See:  http://www.medicalnewstoday.com/articles/30694.php
Thanks,
68.123.227.114 (talk) 00:06, 7 March 2010 (UTC)
thread_title: Untitled
Talk:Interactome

message: Disclaimer: I am not a biologist.
It seems implicit in this page that an Interactome, perhaps like a genome, is a body of information about some particular species.
If so this should be made explicit.
If this is so the following question is begged:
  If protein X impacts protein Y in species A,
  why does it not impact it in species B?
Hopefully there is a short list of such known or proposed mechanisms and the list should be mentioned.
I have recently heard a theory, whose name I have forgotten, that introns in the DNA (near the expressor gene of the impacted protein) may control such impact and thus are interactomes inherited.
76.220.201.192 (talk) 02:55, 10 June 2008 (UTC)
thread_title: Untitled

message: The third paragraph of this section talks about "the interactome" as if there were only one. It talks about "it" being incomplete as of October 2010. But the paragraph never describes WHAT interactome it's referring to. I originally thought that it was referring to the interactome in the prior paragraph related to Budding yeast, but that's not very clear. And, given that the paragraph has only one citation (that doesn't work), I can't really find a way back to the original source material.  SeanAhern (talk) 17:53, 1 October 2012 (UTC)
thread_title:  Genetic interaction networks confusion? 

message: Term not used by any source other than the authors of the article; at most, it should be mentioned as a suggested term at interactome. הסרפד (call me Hasirpad) 15:43, 24 May 2019 (UTC)
replies: text: Agreed,  done! Amkilpatrick (talk) 16:08, 24 May 2019 (UTC)
thread_title:  Proposed merge with [[Hypothome]]
Talk:Perazzi

message: I am a relatively new user to wikipedia and i will be happy to make it more  like an encyclopedia entry. if there is a link on how to do that, it would be extremely helpful. I thank you for your consideration. J.Mraz 02:06, 16 February 2007 (UTC)
replies: text: Message left on editor's talk page. KillerChihuahua?!? 02:34, 16 February 2007 (UTC)
thread_title:  New user help
Talk:K252a

message: K252a does not mimic Neurotrophins in PC12 cells.  It is staurosporine that can mimic NGF in certain processes in PC12 cells.  K252a has no such effect.  
AS Tischler, LA Ruzicka, PR Dobner.  A protein kinase inhibitor, staurosporine, mimics nerve growth factor induction of neurotensin/neuromedin N gene expression. 1991. J Biol Chem  266: 1141-1146.
149.125.202.202 (talk) 11:19, 30 November 2009 (UTC)
thread_title:  Error in page
Wikipedia talk:WikiProject Australian history/Earthquake and landslide disasters

message: This article presupposes events with subsequent effect upon population  - what about events that are notable but minimal impact - should they be listed elsewhere? SatuSuro 02:07, 16 February 2007 (UTC)
replies: text: This page as it stands right now is a listing of events as detailed under Events By Category at the Emergency Management Australia - Disasters database. As the editor who made the differentiation between the so-called major and minor, be assured that it was purely arbitrary. The list really was created as a resource for editors interested in the history of Australian disasters, and should be gone through more carefully. I could imagine that notability exists in some of the minor events. If so, they should be moved to the major section, and maybe a short blurb about why - better yet, create a stub article. Cheers.SauliH 06:27, 16 February 2007 (UTC)
thread_title: Disaster/ vs event
Talk:Brad Sykes

message: Skyes or Sykes?? The JPStalk to me 02:07, 16 February 2007 (UTC)
thread_title: Untitled

message: The standard of writing in this article is patchy at best, and reads more like a promotional exercise than an encyclopedia. For example - first line in the Biography section says "camera at age 15 and has not stopped shooting since". The 'not stopped shooting since' just seems a bit excessive, it has undertones of "this is all that the director ever does, he is so committed to his work". I don't think it's appropriate on Wikipedia. 213.107.102.188 (talk) 01:14, 19 November 2013 (UTC)
thread_title:  Promotional Biography
Talk:Samuel Chadwick

message: The Samuel Chadwick page does not have any references.  What are the sources for this material? — Preceding unsigned comment added by 70.110.59.96 (talk) 02:08, 16 February 2007 (UTC)
thread_title: Pacific messenger
Talk:Ocracoke Inlet

message: First of all, an inlet doesn't have to earn a living.  People earn a living.  Secondly, I tried to decipher the latter half of the sentence into something more coherent, and was unable to.  Help?  SchuminWeb (Talk) 19:37, 25 April 2007 (UTC)
replies: text: Thanks.  SchuminWeb (Talk) 03:07, 26 April 2007 (UTC)
thread_title:  Confusing tag 
Talk:Lability

message: The introductory section consists of this one sentence:
"Lability refers to something that is constantly undergoing change or is likely to undergo change."
No, it does not.
It refers to the state of constantly undergoing change. 
If you can't write an accurate definition of a concept, it is much better to write nothing. 2601:200:C000:1A0:B4E6:9BA4:980:C6B4 (talk) 19:39, 2 August 2021 (UTC)
thread_title:  Bad introduction
Talk:Leukopoiesis

message: I removed this:
"On the basis of the history of associated leukemic diseases, it's divided into two main groups: acute and chronic. The incidence of both chronic and acute leukaemias is higher in males than in females."
Leukemia (a pathology) is only tangentially related, and this sentence did not belong out of context here.This page needs work and erythropoesis is a reasonable page to reference as a template for this one. Egious (talk) 12:46, 3 September 2022 (UTC)
thread_title:  Leukemia
Talk:Lymphotoxin

message: Hello,
While other pages exist for both lymphotoxin alpha and lymphotoxin beta, on this page I plan to provide a general overview about the lymphotoxin protein, its role as a cytokine in the immune system, and a description of each type. I will also elaborate on lymphotoxin involvement in health issues such as cancer and viral infections, and how the protein can be used for treatment of these conditions and related health issues. Below is a list of sources I will use to support the information added.
* 
* 
* 
* 
Please let me know if there are additional articles that would benefit the information on this page or if there are any concerns about the listed sources.  
Immcarle115 (talk) 20:22, 2 February 2020 (UTC)
thread_title: Untitled
Talk:Lysis buffer

message: 1. General description of lysis buffer
   The definition of lysis buffer, general functions, classification, and usage.
   Almost all the existing content will be preserved in this section
2. Buffer without detergent
   Their primary experimental functions 
   Cases (examples) where they are used 
   Commonly used recipes 
3. Buffer with detergent
   Their primary functions 
   Cases (examples) where they are used
   Common recipes  
CindyLi2016 (talk) 04:38, 9 February 2016 (UTC)
thread_title:  Proposed Edition Plan
Talk:MES (buffer)

message: There aren't any other things that are buffers or related to buffers that might need articles on Wikipedia, so I removed the disambiguating hatnote that wasn't disambiguating anything. See WP:NAMB. This situation didn't seem to come close to the exceptional circumstances for leaving them mentioned in that policy (especially, as this article doesn't have high SERP ranking).
Llew Mawr (talk) 16:20, 5 March 2018 (UTC)
thread_title:  Removed hatnote
Talk:Fairmont State Airfield

message: Project Fillmore County
		This article is part of Project Fillmore County, a project created to bring all sites listed on the National Register of Historic Places in Fillmore County, Nebraska up to Good Article or Featured Article status. The project needs your help! If you wish to sign up and help, please do so here.
- Awardgive. Help out with Project Fillmore County 03:21, 15 April 2013 (UTC)
thread_title: Project Fillmore County
Talk:MtG Editor

message: Is this notable?  I participated in Wikipedia:Articles for deletion/Apprentice (software), and if one of the major third-party MtG software required such a huge battle to get no consensus, it seems pretty unlikely that this minor product is notable.  Also, sources probably hard to come by in English.  Maybe on the German Wikipedia?  Can this article be sourced better from non-first party sources?  SnowFire 02:15, 16 February 2007 (UTC)
Talk:Herb Sheldon

message: Not being the author, I could--and did--remove the tag. On comparing the present state of the article with the tv.com source, I found that the article was indeed based on it, but did not use the same words, did not use the sentence structure or the paragraph structure. and was a very appropriate selection of the high points, as compared with the great mass of detail in the source. Only smilarity was that they were arranged chronologically, which is inevitable in a bio. (Probably the article was further improved from when the tag was added)
Article still needs some more sources, but an intelligent start. DGG 02:15, 16 February 2007 (UTC)
replies: text: I disagree. It needs a rewrite--you need to paraphrase everything, not just switch around some words here and there, and if you want to keep the article, you should be willing to do it. grendel|khan 05:26, 16 February 2007 (UTC)
replies: text: Did a little more. Of the 2 or 3 people a day that I spot who shouldn't have been prodded/speedied,  I rewrite about one a day, often for an over-modest academic. I notice others incidentally, but though I can help a little, I can't myself rewrite all the stuff that needs it & I usually stay close to my main interests, and childrens TV is not one of them. I do not think the current state of the article follows the source closely enough for plagiarism--but I accept that we may not agree--if you still think its too close, nominate it for Afd.  It may or may not survive AfD, but I'll have given it a chance to be seen and fixed. DGG 06:54, 17 February 2007 (UTC)
thread_title: Untitled