Talk:Sodium/potassium/calcium exchanger 5

message: Is there any information on when did the mutation that originated the threonine allele happen?
:As it says in the article, "5,300 to 12,000 years ago" Pstanton 07:16, 10 January 2009 (UTC)
thread_title: When?

message: According to , "solute carrier family 24 member 5" is an accepted alternated name for the "sodium/potassium/calcium exchanger 5" (NCKX5) protein. Of course, "solute carrier family 24, member 5" is also the approved HUGO gene name (see ). So the protein and gene names overlap. As discussed here and here, we have tried to make clear in the lead that the scope of Gene Wiki articles encompasses (1) both the gene and the protein encoded by that gene and (2) not only the human gene/protein, but also orthologs that exist in other species.  The wording that was reached through consensus is perhaps a little awkward, but it is both accurate and concise:
* <recommended UniProt name> is a protein that in humans is encoded by the <approved HUGO gene symbol> gene.
The "that" in the above sentence is non-limiting implying that the protein (and gene) exists in other species besides human. Boghog (talk) 11:15, 27 October 2010 (UTC)
thread_title:  Gene and protein names 

message: The mapped frequencies for areas in the southern Indian subcontinent appear to be not entirely representative. The derived SLC24A5 allele has been observed at frequencies of around 50% among Sinhalese and about 18% among Tamils  . Soupforone (talk) 04:04, 2 September 2017 (UTC)
thread_title: Frequency map

message: From the article, "Tests for this variation have obvious application to forensic science." I'm a geneticist and I find this condescending and insufficiently specified.  — Preceding unsigned comment added by 24.182.18.253 (talk) 03:49, 7 April 2019 (UTC)
replies: text: Removed. Boghog (talk) 04:18, 7 April 2019 (UTC)
replies: text:  Reinstated with more accurate and specific wording, plus sources Tobus (talk) 05:47, 7 April 2019 (UTC)
thread_title: "obvious"

message: The intro states that the SLC24A5 gene has been the subject of "recent" selection for skin color in Europe. How recent is that? The Beleza, et al, article footnote 9 indicates 11-19K years ago, for just that gene, while skin color selection has gone on much longer. I suggest putting a more concrete time period on it. I've had students who think that The Beatles are ancient history. Dynasteria (talk) 18:38, 30 May 2021 (UTC)
replies: text: I've updated it with the most recent studies that suggest ongoing selection over the last 5,000 years (plus added recent information of the alleles prevalence in Khoisan people). Tobus (talk) 00:09, 31 May 2021 (UTC)
replies: text: I concur. Would it be appropriate to add the time of origin? Dynasteria (talk) 08:15, 31 May 2021 (UTC)
thread_title:  Recent? 

message: The footnotes seem out of whack. I can't find 1-4 or 8 in the article itself. I'd attempt to fix it but have no idea how. Dynasteria (talk) 18:44, 30 May 2021 (UTC)
replies: text: If you click the "^" or "a"/"b"/"c" etc. at the start of each reference it takes you to the place in the text where it is used. 1-4 are in the infobox on the right hand side. 8 is in the 1st sentence of the 2nd para in the lead (after "between Europeans and West Africans.") Tobus (talk) 00:13, 31 May 2021 (UTC)
replies: text: Thanks. I see them now. Dynasteria (talk) 08:03, 31 May 2021 (UTC)
thread_title:  Footnotes