Talk:Testicular cancer

message: From  article:
	Worldwide incidence has doubled since the 1960s, with the highest rates of prevalence in Scandinavia, Germany, and New Zealand. Testicular cancer is uncommon in Asia and Africa.
There does not seem to be a good explanation for this. Many articles  say that birth cohort has a major influence. Another , if I read it correctly, find a slight correlation between TC and BMI, and TC and height. And why could incidence possibly be decreasing in Denmark  ?
I would like to improve the prevalence and distribution section of the article. Are there any theories I missed out? Similarly, have some things like diet or pesticide ingestion been shown to have no influence on testicular cancer at all?
-- Stereo  (talk)  09:45, 4 January 2007 (UTC)
thread_title:  Unexplained incidence increase 

message: (This section was removed because it was unreferenced and remained so for three months. --Captaindan 04:46, 30 January 2007 (UTC)
thread_title: Alternative therapies

message: This is an odd symptom to list. I've never heard of it as a TC symptom, and so I decided to look around online and they're never actually connected. It's a frequent worry apparently, since that's a scary symptom to have, but from my reading it's more indicative of a urinary tract infection, and really no more serious than a bloody nose. Consider this article from the Mayo Clinic What causes blood in semen? It's not listed as a symptom here, or here, and here it's listed as NOT a symptom. I'm going to take the symptom out, and if anyone wants to put it back in, I'd like to see a cite where this is a concrete symptom of TC. --Boradis 23:41, 2 February 2007 (UTC)
replies: text: Thanks for the cite on the symptom, I've corrected the way it was placed and it works now. There seems to be some disagreement about this issue between the US and the UK. I'm more and more of the opinion that Wikipedia is the absolute LAST place to go to learn about medical issues. --Boradis 23:27, 9 February 2007 (UTC)
replies: text: And I say the above because a page like this really needs a fully qualified and responsible MD reviewing and maintaining it. Us average Web shmoes aren't qualified to weigh these issues and make judgment calls about which symptoms are noteworthy or not. --Boradis 23:30, 9 February 2007 (UTC)

text: We have already discussed this. Please find a citation, and please sign your comments. —Captaindan 17:59, 14 February 2007 (UTC)
thread_title:  Blood in semen? 

message: Some of the text on this page concerning germ cell tumors probably should be moved to that page.  The text here is a little like blind men describe the elephant:  only part of the story. --Una Smith 02:22, 1 July 2007 (UTC)
thread_title: CLEANUP:  Germ cell tumors

message: The section on staging needs a rewrite.  Staging is not done by a pathologist; the pathologist sees only the in situ tumor, via a specimen.  The pathology specimen might reveal evidence of infiltration into other tissues, but reveals nothing about regional lymph nodes nor distant mestastases.  Staging is a team effort, involving pathologist, radiologist, surgeon(s), and oncologist.  I recommend: leave all detailed explanations of staging to pages describing cancer staging. --Una Smith 16:30, 29 July 2007 (UTC)
thread_title: Staging

message: Is this person actually famous?  Also, the level of detail about his treatment and who he credits for support seems off-topic.  --Intx13 17:07, 30 July 2007 (UTC)
thread_title: Donald H. Bensen

message: Any notes on particular causes of this cancer? Have their been any particular risk factors such as, tight underwear, etc ? Rfwoolf (talk)
:Yes, there are.  I'll add a risk factors section as soon as I gather my sources. Novangelis (talk) 18:16, 20 January 2008 (UTC)
replies: text: I'll look into this.  I need to re-review the association with vasectomy which is related to the discussion of displaced seminal fluid.  I need to look at the data before making a statement regarding vasectomy.  I added some material, but couldn't find the paper I was looking for.Novangelis (talk) 05:24, 23 January 2008 (UTC)
replies: text: According to Harrison's Principles of Internal Medicine, the causes are cryptorchism and isochromosome of the short arm of chromosome 12 are the main associations; excess copy number of 12p occurs in nearly all germ cell tumors. Several years ago, people were saying that excess testosterone, as in testosterone supplements, can increase the incidence of testicular cancer, but I don't know if they ever found good evidence. You might see a reference to it on the package insert of testosterone supplements. Nbauman (talk) 05:44, 23 January 2008 (UTC)
replies: text: I read the Harrison's article.  They had more risk factors in previous editions, but some recent articles have shaken up the traditional associations.  The excess 12p is a rearrangement found in the tumor cells, but is not a risk factor.  Determining the key genes in the rearrangement will provide a better understanding of the molecular pathogenesis.  That's another aspect. Novangelis (talk) 06:36, 23 January 2008 (UTC)
thread_title:  Causes 

message: I pulled his inclusion from the list of notable survivors as he had lymphoma, as discussed in Our Cancer Year.  Lymphoma can affect the testes, but is a different entity.  I suggest documentation if he did, in fact, have testicular cancer, not just involvement. Novangelis (talk) 22:23, 15 February 2008 (UTC)
thread_title:  [[Harvey Pekar]] 

message: Article says 1 in 250 men develop testicular cancer. There were 138 million men in the 2000 census. That means roughly 552,000 men get it in their life. Roughly an American life is 74 years, so there should be no more than 7459 diagnosis/year, not 8,000 to 9,000 as the article states.
71.198.177.64 (talk) 11:28, 25 March 2008 (UTC)
replies: text: It is roughly 1 in 250, as the article states.  If it were 1 in 200, there would be over 9,000 cases.  The conservative round number is the one generally used.  Your observation is well founded.  I plan to review the literature a bit to see if the number has changed.  It was <9000 in 2004, but the 2000 numbers will align with the census.  For now, I don't recommend an uncited change (use a number from the relevant literature).  This is a matter of being imprecise, not inaccurate and 1 in 250 often is better understood than 0.4%.  Using 1 in 225 (0.45%) would be more accurate, but overly precise.  Given the incidence has increased in recent years, the numbers should be checked.  Thank you for taking a good look at the article and looking for ways to improve it.Novangelis (talk) 12:37, 25 March 2008 (UTC)
replies: text: I finally got around to checking the numbers and you were right.  I cited ACS numbers for 2003 and 2007, being the first and last to use the 2000 census data.  Although the data does not affect raw number of cases, it may impact population derived statistics if used later in the article.  I've broadened the range around my two timepoints, 7,600 (2003) and 7,920 (2007).  I'd suggest that anyone using the ACS Cancer Facts and Figures not go back past 2003, especially if using population dependent numbers.Novangelis (talk) 20:00, 24 April 2008 (UTC)
thread_title: Figures do not add

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replies: text: In instances like that, it's often best to link to an 'information' or 'FAQ' page, instead of the main page or a forum page.  Editors that do a lot of anti-spam work at Wikipedia are usually going to give a site about three seconds' attention.  So you want the page you link to be as obviously informative and non-banned as possible.  WhatamIdoing (talk) 01:14, 29 January 2009 (UTC)
thread_title: External links

message: According to the BBC a former welsh international soccer player has just been diagnosed with the cancer.
Hartson is only 34 and was showing traditional the symptoms associated with the disease. However in his case it has metastasized and spread to the brain.
News article  —Preceding unsigned comment added by 217.42.254.87 (talk) 13:46, 13 July 2009 (UTC)
thread_title:  [[John Hartson]] 

message: This section does not contain prognosis for any of the Stages, so I'm unclear as to the heading of the section.Corymichael780 (talk) 16:48, 25 July 2010 (UTC)
thread_title:  Prognosis 

message: There have been several edits to this page and (not surprisingly) Quarter (United States coin) that appear to be original research linking testicular cancer to carrying quarters around in your pockets. "Original research" includes scientific studies that are not supported or recognized by sources outside of the organization conducting the study. The external links that were put here were simply research materials that do not directly support the content, and are not valid as either citations or external links as such. If there are reliable sources to back these entries with inline citations, they should stay. Without them, they cannot. Cheers :> Doc talk 06:29, 11 March 2011 (UTC)
thread_title:  March 2011 

message: I took a look at this list, and was struck by one overwhelming observation: the massive dominance of professional road race cyclists. That is particularly striking as it's not a sport that has a lot of pros, and yet there are 4 on the list. That immediately suggests that there might be a link. It could be the saddles -- we know that there is a link between narrow bike saddles and male reproductive system harm -- but certainly what sprung to my mind was the issue of performance enhancing drugs; I think of road cycling as the serious sport in which popular wisdom has it that doping is most common. And then, most of the other people on the list are also sportsmen, and also in sports that have a checkered history when it comes to steroid usage. It seems to make sense, too: use of artificial hormones mimicking those naturally produced in the testes could reasonably be linked to problems in cell growth there.
I also noticed that the list of famous survivors was discussed on the talk page back in 2008, so out of interest I checked the history. The old list was overlong and poorly formatted but showed no such bias.
Therefore, I believe that my hasty conclusion linking testicular cancer to cycling was mistaken. The real link, if any, is probably to Lance Armstrong -- by far the most famous road cyclist of recent years, and well known as a testicular cancer survivor and head of his LiveStrong foundation speaking out on such issues. I think that the leadership of such a star in the sport might bring other cyclists diagnosed with testicular cancer into the limelight; and while it's not such a mass sport, there are enough that 4 on the list could be within the same statistical 0.4% as the population at large.
I think this is a major issue that needs to be addressed in the article. The erroneous conclusion that I reached makes sense based on the information provided, and I would expect other people to reach it independently. The result is a smear on the reputation of these people, and of any sportsperson who is diagnosed with testicular cancer. I think that the presence of the list does add to the article, but I would suggest dropping some of the cyclists and bringing back some people from areas outside sports. That would help show that testicular cancer is common, that it should carry no stigma, and that people can be treated and return to an active and successful life in any field. 201.230.79.114 (talk) 04:08, 1 July 2011 (UTC)
thread_title:  Famous survivors 

message: I'm not sure how this section tallies with what is written on Cancer Research UK's website http://cancerhelp.cancerresearchuk.org/type/testicular-cancer/about/types-of-testicular-cancer 
Wiki:
"More than 95% of testicular cancers are germ cell tumors. Most of the remaining 5% are sex cord-gonadal stromal tumours derived from Leydig cells or Sertoli cells."
CRUK:
There are two main types of testicular cancer - Seminomas & Non seminomas. They develop from germ cells in the testes. Between 40 and 45 out of every 100 testicular cancers (40 to 45%) are pure seminomas. Most of the rest are mixtures of these other types of non seminoma testicular cancers.
Any thoughts on how to clarify? HenryScow (talk) 12:57, 13 July 2011 (UTC)
thread_title:  Classification 

message: As part of Cancer Research UK's involvement with Wikipedia, we're looking into improving the info on this page, particularly for a non-medical audience. Any issues/feedback, pop a comment below or on my talk page HenryScow (talk) 13:04, 10 August 2011 (UTC)
thread_title:  Recent edits 

message: I lost one of my testicles when I was a child due to it ascending into my body and not being salvagable (I had to have it removed). I find it incredibly annoying that, no matter how heard I search, I cannot find any information on testicular cancer when you only have one testicle, e.g. how am I supposed to compare the size of my testicle against the other when it has long been incinerated! I would appreciate it if consideration could be given into having a section on here dealing with this issue.  — Preceding unsigned comment added by 88.109.19.51 (talk) 19:11, 30 January 2013 (UTC)
thread_title:  Only have one

message: Is there any way to prevent it? Just that (I think is very important this issue).--179.37.144.76 (talk) 03:37, 15 March 2017 (UTC)
thread_title:  Is there any way to prevent it? 

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thread_title:  External links modified 

message: "Since seminoma can recur decades after the primary tumor is removed, patients receiving adjuvant chemotherapy should remain vigilant and not assume they are cured 5 years after treatment.[citation needed]" -- I'd say this should be removed, as there's no citation and it's sort of needlessly anxiety-inducing. Most cancer could, theoretically, recur decades later; without a citation backing this up I'm not sure it belongs. Trickycrayon (talk) 14:00, 14 July 2021 (UTC)
thread_title:  Assertions on long-term seminoma recurrence 

message: Do we really need to have that greeting people who are likely coming here to learn about the cancer they've just been diagnosed with? 
It's about as bad as a shock site . 2602:306:BC74:6240:1838:AA5F:1B84:12EB (talk) 06:47, 5 December 2022 (UTC)
thread_title:  Can we do something about that disgusting photo? 

message: May information be added describing when Testicular cancer was first diagnosed? (Month, year and country, if possible.) Centauri4 (talk) 18:39, 14 December 2022 (UTC)
thread_title:  History 

message: — Assignment last updated by Dandelions-love-to-fly (talk) 21:09, 15 March 2024 (UTC)
thread_title: Wiki Education assignment: The Impact of Cancer