Talk:Insulinoma

message: Thanks for taking the trouble to tidy up the article. But, and correct me if I'm wrong, I thought Wikipedia had a policy of allowing articles to be continued in the particular flavour of Englsh they were first started in?  Ianmc   Wikipedia:Contributing_FAQ#Should_I_use_American_English_or_British_English.3F
Hi.  I've replaced the stub with an article.  Stupid me, I forgot to log in before pasted the article in. Cybergoth 03:12, 3 September 2005 (UTC)
thread_title: Thanks

message: The criteria in Whipple's Triad for a diagnosis of Hypoglycemia is not circle thinking.  Some people have a normally low glucose level (often women) without symptoms.  This would not be considered clinically important hypoglycemia, and would not likely be due to a disease like an insulinoma.  The distiction is therefore between "clinically important" hypoglycemia versus a "label" of hypoglycemia due to a blood test report. - Cybergoth 18:36, 18 June 2006 (UTC)
replies: text:  Come on, I added a lot of stuff to the article. Would you be so amiable and not revert but edit? You threw away all my edits by this rv. ackoz  20:37, 18 June 2006 (UTC)
replies: text:  Sorry you didn't. My bad. ackoz  20:38, 18 June 2006 (UTC)
thread_title:  Whipple's triad 

message: Warner ("Enteroendocrine Tumors Other Than Carcinoid: A Review of Clinically Significant Advances" by Richard P. Warner), after a review of the literature on incidence, says that "Clinically significant PETs have been reported to occur in approximately 1 per 100,000 people per year". "PET" means pancreatic endocrine tumor, synonymous, I believe, with "tumours arising from the islets of Langerhans cells". One per 100,000 is 3000 per 300 million (population of USA). 
Warner also says that "Nonfunctioning PETs comprise the largest group of these tumors, 15% to 30%", and "Insulinomas are the most common functioning PETs with a 17% incidence". 
If nonfunctioning are 15% of PETs, and insulinomas are 17% of the remainder,
then insulinomas are 14% of the total.
If nonfunctioning are 30%, and insulinomas are 17% of the remainder,
then insulinomas are 12% of the total.
Let's average 14% and 12% to 15%. Thus there would be 15 percent of 3000, or 450,
new cases of insulinoma per year in the United States. 
Warner's 450 new insulinomas per year is off by a factor of almost three (meaning: pretty close) from Service's Mayo Clinic value of 4 * 300 = 1200: "The incidence of insulinoma among residents of Olmsted County increased during
the study period to a stable level during the last 2 decades of 4 cases per 1 million person-years" ("Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study" by Service FJ, et alia). 
TH 20:02, 25 July 2006 (UTC)
thread_title:  incidence 

message: See the neuroendocrine tumor discussion page for statistical citations (incidence and malignancy).
I invite all interested parties to edit or criticize neuroendocrine tumor. Citations are on its discussion page.
TH 02:36, 16 August 2006 (UTC)
thread_title:  please check Neuroendocrine Tumor article 

message: Are they? Wiki CRUK John (talk) 16:47, 16 October 2014 (UTC)
thread_title:  Always malignant?