Talk:Acetylcarnitine

message: I don't quite understand the following phrase. Could it be clarified, or corrected?
"The L-carnitine is cycled back into the mitochondria by transporting more acyl groups..."
Briancady413 (talk) 19:16, 20 January 2010 (UTC)
thread_title: Untitled

message: If proper citations are not provided within a week, i'll remove all of that text. -- Boris 15:53, 11 June 2006 (UTC)
replies: text: Done. The citations I found that were not from dubious manufacturers' pages indicated that whatever benefits might be had, apart from end-stage renal disease and PAD, were inconclusive at best. I've made some changes to the text and added some sources, so as to not have the edit reverted as vandalism when it is indeed just removing unsupported claims. Zuiram 11:11, 1 October 2006 (UTC)
thread_title: Citations

message: http://onlinelibrary.wiley.com/doi/10.1196/annals.1403.019/full ... Nagelfar (talk) 23:49, 14 February 2012 (UTC)
thread_title:  "Valproate and Acetyl-l-carnitine Prevent Methamphetamine-Induced Behavioral Sensitization in Mice" 

message: The "Health claims" section seems to be just a poor copy of Carnitine#Potential_uses_as_a_pharmaceutical.
Does Acetylcarnitine actually have any benefits that are specific to it (i.e. you get them from Acetylcarnitine but not from L-carnitine)?
If not then this article should just say that the health benefits are the same as carnitine, instead of having a poor copy. Gronky (talk) 03:28, 4 January 2013 (UTC)
thread_title:  Health claims same as [[Carnitine]]? 

message: I am not qualified to properly evaluate the applicability of the info from the following link to this article.  Here's the link:
Forbe's article linking carnitine to artherosclerosis
Can someone please have a look?  Thank you, Peatbog (talk) 22:31, 7 April 2013 (UTC)
thread_title:  Report of new research, April 7, 2013 

message: I have removed the content below from the article space:
ALCAR has been shown to be more effective than tamoxifen in improving the curvature and reducing the pain and plaque sizes for men who sought treatment for their Peyronie's disease early and having low curvature deformities.
;Discussion
* The face the editor has left their Google Books search text ("Carnitine improves libido") in the text does not give confidence. More generally, is this reliably sourced? Alexbrn talk|contribs|COI 07:20, 31 March 2014 (UTC)
thread_title:  Peyronie's disease 

message: This article has been revised as part of a large-scale clean-up project of multiple article copyright infringement. (See the investigation subpage) Earlier text must not be restored, unless it can be verified to be free of infringement. For legal reasons, Wikipedia cannot accept copyrighted text or images borrowed from other web sites or printed material; such additions must be deleted. Contributors may use sources as a source of information, but not as a source of sentences or phrases. Accordingly, the material may be rewritten, but only if it does not infringe on the copyright of the original or plagiarize from that source. Please see our guideline on non-free text for how to properly implement limited quotations of copyrighted text. Wikipedia takes copyright violations very seriously. Moneytrees🌴Talk🌲Help out at CCI!  21:44, 29 April 2020 (UTC)
thread_title:  Possible copyright problem 

message: *Acetyl-L-Carnitine Supplementation and the Treatment of Depressive Symptoms: A Systematic Review and Meta-Analysis (2018) - is this a good-quality meta-analysis worthy of inclusion into the article, or is it low-quality? ---CopperKettle 13:47, 23 May 2020 (UTC)
thread_title:  2018 meta-analysis on depression 

message: I find the alternating use of Acyl and Acetyl confusing. While Acyl may be correct in modern usage, it is non-IUPAC, unfamiliar to me (a graduate chemist), and appears to be a typo to one not accustomed to the term. The article title is Acetylcarnitine, the compound is given in the header as 'Acetyl-L-carnitine'—why not stay with 'acetyl' for simplicity and clarity's sake? Add your comments, agree or disagree....
:It gets worse: there's a dictionary out there, apparently authoritative, THE AMERICAN HERITAGE® SCIENCE DICTIONARY, cited in dictionary.com no less, which defines "acyl" as "...containing the group RCO, where R is a halogen." [emphasis mine]. That's not a definition of "acyl", that's an acyl halide, a completely different animal. That could really confuse someone who happened to look up the term there! I maintain that the use of "acyl" in the article is confusing to the lay reader & should be replaced. It is a 19th century German coinage, of limited English use; if you want to get technical, say "alkanoyl" or "alkyl carbonyl" with some mention of what the alkyl group can be.  I am reluctant to do the edit myself as I am unclear as to how general "acyl" is intended to be here: is it just acetyl without the —OH, or are there other —RC=O groups implied, and if so, what Rs? I wouldn't touch this without a bunch of literature research, so I hope the original editor stops by, or someone familiar with the biochemistry of this class of compound. --D Anthony Patriarche (talk) 21:00, 5 May 2022 (UTC)
thread_title:  Acyl vs Acetyl