lflage/wiki-talks huggingface dataset:
Talk:Howard Vernon (Australian actor)

message: Surprised at the deletion of Everett's appraisal of Vernon as "redundant and trivial". They were with JCW together 1893–98, she as ballet mistress in the latter years. Doug butler (talk) 02:32, 20 March 2022 (UTC)
replies: text: It is redundant because we have other critical assesments of him.  It is trivial, because she is just a fellow performer, not a critic, and her assessment of him is not independent.  Plus, what she said is pretty obvious, because the patter character in G&S always has a "dominating presence" in the G&S operas.  It is the equivalent of saying that Tina Fey thinks Alec Baldwin is cool and had a dominating presence in 30 Rock. -- Ssilvers (talk) 02:41, 20 March 2022 (UTC)
replies: text: Who's . . . (never mind) Doug butler (talk) 03:07, 20 March 2022 (UTC)
thread_title:  Minnie Everett
Talk:Howard W. Hunter

message: An inquiry by  was received at Wikipedia:Reliable_sources/Noticeboard#Howard_W._Hunter with respect to use of The Deseret News as a source for information in this article. It did not contain sufficient detail to form the basis of a discussion there and was closed. What are the problems, if any? User:Fred Bauder Talk 15:08, 25 June 2012 (UTC)
replies: text: Please disregard the above. Gtwfan52 (talk) 20:02, 25 June 2012 (UTC)
thread_title: Reliable sources discussion

message: He had 3 kids. There's no record of the name Cody Howard.  — Preceding unsigned comment added by Backpack1988 (talk • contribs) 16:12, 25 March 2018 (UTC)
thread_title:  Howard Hunter
Talk:Α-Methylfentanyl

message: It says that "AMF is less potent by weight" whereas it is actually at least three times the potency of fentanyl.
:Well that is a very important discrepancy, please source that if you can and edit the article accordingly. Nagelfar (talk) 06:13, 8 November 2008 (UTC)

message: The article states that Chinese Rock (as a-Methylfentanyl) began to appear in 1976 in Orange County, CA.  This is not the earliest known usage by a long shot.  It was widely used in the New York Bowery in the early 1970s; by 1975 punk rock icons The Ramones, Richard Hell, and Johnny Thunders had immortalized Chinese Rock in a song called, "Chinese Rock."  (Sample lyrics:  "Ya wanna go take a walk, ya wanna go cop?  Ya wanna go get some Chinese rock?") See [] for more.  Galaxiana (talk) 01:45, 24 December 2015 (UTC)
thread_title:  Chinese Rock has been known since 1975 at least 

message: There are 2 isomers. This is an important fact to students. The drug cannot be produced in a chiral manner & partial crystalization would result in losing 50& of the less-potent isomer. Adding is of no value to clandestine chemists since their is no practical solution. Even if someone went to the trouble of isolating the isomers, tautaumerism is not going to work well and you would have to recrystalize many times, with mechanical losses on each loop. It would be x10 more work than the original synthesis.  — Preceding unsigned comment added by 81.99.74.135 (talk) 14:08, 14 April 2017 (UTC)
thread_title:  Isomers
Talk:Naphthylaminopropane

message: The correct name is "naphthylaminopropane" (with two h), not "napthylaminopropane". Somebody with enough privileges should change the name of the article.  —Preceding unsigned comment added by 85.58.27.10 (talk) 12:48, 2 September 2009 (UTC)
thread_title:  Name error 

message: This would explain the euphoria of phenmetrazine, but not why cocaine is preferred over methylphenidate, etc. Perhaps it is certain SERT receptors only that result in habituation, or certain indirect SERT agonism satisfies more fully, or (and this is likely in my opinion as a firm believer in habituation around metabolic osmosis) the body gauges serotonin depletion with more earnesty & seriousness than the more easily developed endogenous precursors to dopamine. Perhaps it is that cocaine inhibits the reuptake of serotonin only; perhaps a dopamine releaser that is somehow also a serotonin reuptake inhibitor would create the most reinforcement.(?) Napthylaminopropane is a non-neurotoxic DA releaser, does this mean it releases DA by a process other than phosphorylation? Nagelfar (talk) 06:18, 11 July 2010 (UTC)
thread_title:  DAT & NET but not SERT for habituation?
Talk:Hu Harries

message: Hu Harries was the father of six children: Tommy (died age 4 from Polio), Bruce, Jody, Lori, Jeffrey, Daniel.
Jeffharries 13:42, 8 September 2007 (UTC)
thread_title: Untitled
Talk:Fidei depositum

message: I don't see the usefulness of this article.  Its content really belongs entirely to the article on the Catechism of the Catholic Church.  Lima (talk) 09:48, 9 September 2009 (UTC)
replies: text: If this article just reproduces material there, then a redirect seems ideal.  Currently there is just a one sentence mention, but that can be fixed.  Baccyak4H (Yak!) 13:54, 9 September 2009 (UTC)
thread_title:  Needless article? 

message: :Fidei Depositum deserves its own page because it's an independent piece of canonical legislation to promulgate an independent document of Church Teaching. CanonLawJunkie (talk) 14:48, 14 August 2010 (UTC)
replies: text: So five and a half years later...I just merged the content of this page with Pope John Paul II#Catechism of the Catholic Church. There was no section on his role in its publication, and the little lead on this page was perfect. Obviously, I now agree with the above suggestion of merging this page, contra my opinion of 5.5 years ago.  Canon Law Junkie §§§ Talk 07:01, 31 March 2016 (UTC)
thread_title: Article in need of expansion, not deletion!
Talk:Benzylmorphine

message: May I suggest an additional section heading to this Wikipedia article: 
Mention in Fiction
Peronine is used to treat the semi-conscious, radioactive patient Dr Rayner in the British 1955 movie 'The Atomic Man' (aka 'Timeslip'). It is administered to bring his 'brain time' back into sync with his 'body time'; synchronisation had been lost after Dr Rayner's heart stopped for 7.5 seconds before being re-started in hospital. RaynesParkGuy (talk) 15:40, 3 August 2013 (UTC)
Talk:William Deresiewicz

message: Whether or not WD is non-notable as a professor (one book out with Yale University press) he is a critic with many publications in important and widely read journals including The Nation and the New York Times; comparable to James Wood or Adam Phillips (probably careerwise closest to Joshua Clover). Not quite Terry Eagleton noteriety yet, but definitely worth keeping to expand. Formulafiftypoet 20:08, 18 July 2007 (UTC)
thread_title: Untitled
Talk:3-Methylfentanyl

message: Concerning the quote:
:and is currently a problematic drug of abuse in Scandinavian and Eastern European countries such as Finland[7] and Estonia.[8]
I have done a quick search and cannot fint any evidence of this being true in the case of Scandinavia.
Secondly, Finland is not a part of Scandinavia. I believe this should be edited.
--TheBlurstOfTimes (talk) 13:45, 27 March 2012 (UTC)
thread_title:  Comments 

message: Just as radiation victims get monitored, the >700 Moscow survivors/exposure victims should be monitored for effects. This page should have a section for the long term. 143.232.210.150 (talk) 18:01, 12 June 2012 (UTC)
thread_title:  This page needs a section, perhaps under chemical weapons, on long term effects 

message: There are 4 isomers each with a different actions. The more potent isomers haver a lower duration of action. I think that's worth adding because it helps students while not adding anything og value to clandestime chemists. The 3-methyl-4-piperidone exists as a tautomer i.e. you cannot obtain a single isomer without partial crystalization - and that isn't going to hallen.  — Preceding unsigned comment added by 81.99.74.135 (talk) 14:00, 14 April 2017 (UTC)
thread_title:  Isomers 

message: In the related propiram and phenapromide classes, the 3,3-dimethyl piperidine analogues are more potent than the 3-monomethyl analogues. If you overlay them, you can see why. I think it's safe to make this point because NOBODY is going to make these classes when considering cost and complexity. I think it's somewhere in my patents database BUT they had to make the precursor and the clandestine 'cooks' are nowhere near sophisticated enough to tackle the demanding synthesis. In fact, I sent a list of 624 precursors to the Met so I presume this is already covered (I put a lot of time tying to cover them all).  — Preceding unsigned comment added by 81.99.74.135 (talk) 16:14, 28 May 2017 (UTC)
thread_title:  3,3 Dimethyl
Talk:Quarter glass

message: Alistair Cooke mentioned in one of his 'letters' that Ralph Nader had something to do with removing side vent windows - true? how? I can think they affected visibility via the side view mirror significantly.
??  — Preceding unsigned comment added by Robfwoods (talk • contribs) 07:14, 1 May 2013 (UTC)
thread_title:  Ralph Nader - ?
Talk:Wino

message: Suggestion for new entry:
WINO or Waverers In Name Only, a disparaging term for members of the United States Republican Party who strike the posture of being mavericks on Iraq, of breaking with an unpopular president, and forcing him to change; yet vote against the measure. Compare with RINO and DINO.
From DailyKos 070718:
==
http://www.dailykos.com/storyonly/2007/7/18/114028/718
Protecting their President
by mcjoan
Wed Jul 18, 2007 at 08:41:10 AM PDT
Standing firmly in the slow quicksand of public disapproval and impending electoral defeat, the WINOs, the Waverers in Name Only, voted with their president this morning, blocking passage of the Levin/Reed amendment to the Defense Authorization.
By a vote of 52-47, with 60 "yea" votes required, Republicans filibustered the Levin-Reed amendment to the Defense Authorization bill, thus keeping it from going to an up-or-down vote and effectively killing the measure. Republicans Chuck Hagel (R-NE), Olympia Snowe (R-ME), Gordon Smith (R-OR) and Susan Collins (R-ME) voted with the Democrats.
Lugar and Domenici knew well before the night of debate started that they would oppose any serious effort to change course in Iraq. And Voinovich who got all that great press a few days ago for telling CNN that Bush had screwed up the war?
    Meanwhile, Voinovich -- another allegedly "wavering" Senator -- had this to say about Democratic efforts to vote on Reed-Levin: "You wonder if they are more interested in politics than dealing with the substance of this."
No, the politics on this one was all on the side of the WINOs, who are doing their best to strike the posture of being mavericks on Iraq, of breaking with an unpopular president and forcing him to change. They got a whole lot of free press out of the deal, with the media just eating up the idea of Republicans abandoning the president. Of course, the traditional media is pretty easy to fool. We'll probably continue to see stories highlighting the tough talk of the WINOs. Will we see stories about how they're action belie their "tough" talk, how they have obstructed any real change of policy in Iraq?
Seeing their intransigence in supporting their president over supporting the troops, can anyone really believe that something so magical will have happened by September to change their minds? No, they'll just kick that can a little further down the road. But they have done one critical thing in their actions during this debate. They have fully taken on the mantle of responsibility for the Iraq debacle. It now belongs entirely to them.
==
WoodenBooks 20:09, 18 July 2007 (UTC)
Talk:Hubert-Erwin Meierdress

message: This article is really long for a minor SS officer. What is his significance? Also, why is the article written in such a fawning tone?  —Preceding unsigned comment added by THEMlCK (talk • contribs) 08:59, 16 February 2010 (UTC)
replies: text: Not at all, anonymous IP.  How is this officer truly significant to history?  There are many decorated officers who don't have any articles in Wiki (not that that is a conclusive point.)  Can someone cite a source that is claiming his actions had a significant impact on the war or the occupied countries? HammerFilmFan (talk) 21:31, 14 April 2012 (UTC)
replies: text: I will condense this article further -- it appears that the subject is not notable enough as no citations have been added in the past 9 years (the article has been tagged since 2007). K.e.coffman (talk) 19:48, 12 March 2016 (UTC)
thread_title:  Whats his significance? 

message: Does not meet WP:SOLDIER & significant RS coverage cannot be found:
*link
Hence the redirect. K.e.coffman (talk) 23:25, 21 November 2016 (UTC)
thread_title:  Notability
Talk:Hubert Murray

message: This article is good, so far...if I had a bit more time... . Murray is a bit of an enigma. His writings about Papua (NG had a separate Governor at this time)  reflect a very genuine concern for the natives and how best to bring them into modern times without too much exploitation. He was very much against the use of Pidgin, claiming it would keep Papuans subservient to colonial exploiters. (This has come to be true, although the current exploiters are home-grown colonialists!) The introduction of TV in the 80s has seen a large increase in the numbers of fluent English speakers; something that PNGBC and ABC radio  never achieved. 
Those with a commercial interests in Papua hated Murray.  Murray made regulations in PNG that seem harsh, keeping  villages well away from any colonial settlements and roads. (There's increasing violence in PNG now as squatter settlements around towns become problematic for local councils.) Murray made sure the few whites in Papua had an area safe for themselves and this was enforced by armed police.  P.C. academics from the 60s onwards, in  Australia, like to show these times and Murray in a bad light. In my experience,  such "academics" have resorted to outright lying and references to their works are best avoided.  The works of missionaries can also be a little suspect/biased, although Percy Chatterton is highly regarded.
Murray, and earlier governors, were sensitive to bad press in Australia relating to punative expeditions. This was caused by the  press uproar over the  "Blanche Bay Affair" of 1878 (J. Pac Hist., V24(1),  38-53, 1989).  The missionary George Brown shot a large number of Tolais  as a punishment for cannibalizing several other  missionaries. The press questioned the right of missionaries to go to P/NG in the first place.
A closer look at appointments in the Papuan colonial admin. reveals that a number of family names occur repeatedly.  Nepotism had been around since Day One in Papua.  Sigma-t (talk) 05:58, 30 November 2009 (UTC)
thread_title: Article Good So Far
Talk:11-Hydroxy-THC

message: , I reverted your edits:
* the "in cannabis culture" part is not accurate; it is perhaps called that in cannabis culture, but not exclusively, and so this insertion is needlessly restrictive.
* the metabolism was dumbed down; internal links allow people to preview/navigate and get some more info from the lead if they need it. You removed internal links so people can't learn more.
* the metabolite can be detected in other drug tests besides only blood tests (again, restrictive)
* "oral" and "eaten" are not synonyms; buccal and sublingual are oral routes that are not eaten
I restored the copy edit in the "Research" section.
Kimen8 (talk) 03:43, 14 April 2024 (UTC)
thread_title:  Undid changes
Talk:Jan Józef Lipski

message: I notice that there are a number of external links on this page. Please consider adding this link to an in depth video of Jan Józef Lipski telling his life story. The video is freely available on the Web of Stories website (http://webofstories.com):
* Jan Józef Lipski tells his life story at Web of Stories (video)
Fitzrovia calling (talk) 09:55, 5 May 2011 (UTC)
thread_title:  /* References and further reading */ 
Talk:Jan Koželuh

message: A discussion that may affect the name or title of this article is ongoing here.  Please voice any opinions or concerns on that page.  After the discussion concludes, this article may be moved to a different title, in accordance with Wikipedia's Naming Conventions.  Thank you.  Tennis expert (talk) 19:30, 11 May 2008 (UTC)
thread_title: Discussion concerning this article
Talk:Jan Kubelík

message: I edited the article a few hours ago and found that it jumps back and forth from one thing to another, both in time and in topic, without having proper structure, which will make the article accessible to the reader. I might get around to rewrite the article thoroughly at some point, but at the moment I thought I should comment on this issue.--Atavi (talk) 20:00, 16 July 2008 (UTC)
thread_title: Article structure
Talk:Lasofoxifene

message: I have readded the following link (now reformatted using cite web template):   The reason for including this link is that it is the only place where I could find recent information concerning the development of lasofoxifene. Furthermore the site contains an extensive bibliography of scientific studies on lasofoxifene. Disclaimer: I have no relationship to either Anakena Internet Services, Ligand, or Pfizer. Boghog2 (talk) 07:37, 19 March 2008 (UTC)
thread_title: External links
Talk:Diprenorphine

message: To bring this speculation further with sources, can anyone find bingind affinity and half-life for diprenorphine?--Custoo (talk) 09:36, 15 October 2014 (UTC)
thread_title:  Diprenorphine for human opioid overdose 

message: Article states These super-potent opioids, with the single exception of buprenorphine [...], are not used in humans because the dose for a human is so small that it would be difficult to measure properly. I find this explanation lacking in clarity, sources and seriousness. LD50 of Etorphine is listed as 30 μg, whereas LD50 of Botox is 2 ng/kg, so 200 ng for 100 kg human. Therefore the small amount of substance needed is not the issue. Therapeutic index of Botox is allegedly around 100:1. I could not find the therapeutic index of Etorphine, nor other "super opioids", but some have allegedly unfavourable therapeutic indices, whereas remifentanil (not the faintest, but still used with humans) has an index of 33 000:1. Indices seem independent of potency. There must be a different reason for not using "super opioids". --Waydot (talk) 19:50, 30 August 2018 (UTC)
thread_title:  Super-potent opioids
Talk:Desmetramadol

message: Check what this structure is linked to in PubChem...something is wrong...--ChemSpiderMan (talk) 00:17, 20 December 2007 (UTC)
replies: text: PubChem link fixed.  -- Ed (Edgar181) 16:16, 21 December 2007 (UTC)
thread_title: Untitled

message: The last section is misleading af, as it states that: 
"Desmetramadol has recently been marketed as a currently legal substitute for illegal opioid drugs, either in powder form or mixed into various other preparations. One such blend sold under the brand Krypton and containing powdered kratom leaf (Mitragyna speciosa) laced with desmetramadol was reportedly linked to at least 9 accidental deaths from overdose during 2010–2011."  
My issues are: Where has it been linked to 9 overdoses? In which country? 
Also, 2010 and for a period of 1 year? That seems not only like an old statistic (as it's more than a decade old) but also statistically insignificant (I'd like to know exactly how many of all the regular consumers of Demetramadol died because of their use, WITHIN a SINGLE country or throughout the ENTIRE WORLD, but mentioning the statistics for a SINGLE country, Sweden, is misleading, especially when they're so small, 9 cases in total). 
This paragraph is misleading at best and I'm not saying that new sources should be included or that more sources should be added, all I'm saying is that the paragraph should be rewritten to reflect its real implications more accurately; such as by dropping the phrase "[desmetramadol] has been linked to 9 overdoses", which makes it sound like a global trend and danger when it's just the statistic for a single country (Sweden) for a single year (2010-2011) in numbers which are statistically insignificant (9 cases in total; also, desmettramadol was just "IMPLICATED" in those cases, not the single cause). 
As such, either add more sources or rewrite the paragraph or delete it. 
--177.227.43.185 (talk) 03:36, 3 January 2021 (UTC)
thread_title:  Worries about the last section (specifically the part about overdoses)
Talk:Ro15-4513

message: This sounds like something I'd like to experiment with. Where can I acquire some?
Miserlou 03:10, 6 November 2007 (UTC)
replies: text: A doctor, or Roche Pharmaceutical. Wikipedia is not here to help you get drugs, sorry. --Astavats 22:19, 13 November 2007 (UTC)
thread_title:  Chemical supply 

message: I think the possibilities of using Ro15-4513 as a drug to counteract the effects of alcohol use are no longer the concern of most that use it. Its use as a precursor/template for other drugs aside, the anti-alcohol effects are fading into history and as they do, this article grows out of date. Although the search for a drug that can effectively remove the side-effects of alcohol use is still on, and indeed the addictive and dangerous effects, Ro15-4513 is being pushed forward as an investigative ligand for GABA research. The finer mechanisms of GABAergic transmission, especially concerning the less common receptor subtypes in the limbic system and cortex, are still the subjects of major debate, and ligands selective for different subtypes are helping to pin down the functions of the different receptors, both at the synapse and holistically, as players in emotional control, impulse control or, importantly, vulnerability to addictive behaviour.
Bluefloyd1 (talk) 10:08, 24 April 2008 (UTC)
thread_title:  Research 

message: RO15-4513 is a complex mixed action drug. Depending on the receptor subtype of GABAA, it can function as an partial agonist, partial inverse agonist, or neutral antagonist. It may be misleading to introduce the drug as a weak partial inverse agonist of diazepam sensitive GABAA receptors.  — Preceding unsigned comment added by AstarothN (talk • contribs) 17:11, 4 June 2014 (UTC)
replies: text: In which case, if you can cite that claim then perhaps write it as you have here? Testem (talk) 09:54, 6 June 2014 (UTC)
thread_title:  This is a complex drug
Talk:Hugh Bartlett

message: "He hit Nichols for five fours in an over, Peter Smith for two fours and two sixes off another." says Alan Ross. "H. T. Bartlett hit him (Smith) for 28 in an over in the Gentlemen v. Players match at Lord's in 1938", says Peter Smith's  Wisden obituary Tintin 15:52, 8 August 2013 (UTC)
replies: text: There appears to be backing for both to be correct. The contemporary Wisden report (1939 edition, page 281, Other Matches at Lord's section) says: "Of four 6's which he hit, two were on drives far beyond the longest boundaries and one from Nichols, bowling at the pavilion end, fell on the highest part of the turret at the end of the grandstand. He followed with five 4's in an over from the same bowler, and two 4's and two 6's to the on in the next over from Peter Smith." However, the report next day in The Times reads: "He hit two 6's off consecutive balls off Smith, and the other four balls in that over each counted four runs." Johnlp (talk) 14:02, 9 August 2013 (UTC)
replies: text: Thank you. So will add a note about the other version. Tintin 01:10, 10 August 2013 (UTC)
thread_title:  Gentlemen v Players 
Talk:Jan Novák (composer)

message: is remarkably similar to the content of the article as it was when Antidote contributed it. They may have ours, but I think it much more likely that we have theirs, given the function of their site. Just sayin'. Schissel | Sound the Note! 18:22, 17 November 2007 (UTC)
thread_title: musica.cz/novakj