Talk:Atheroma

message: I find the information presented in this article to be beyond the scope of its subject.  About half the article is on the clinical aspects of atherosclerosis and therefore belongs in the atherosclerosis article.  The ICD codes belong there too. On the other had there is a lot of information in that article that would enrich this one.    --InfoCan 16:29, 12 June 2006 (UTC)
thread_title:  Atheroma vs. Atherosclerosis 

message: despite the opening sentence containing the addendum typical for most humans, there is neither cross-cultural nor within America's cultural data on the prevalence of the disease.  If this were any other article, that would have already been grounds for a full POV review. <spetz>.216.175.188.98 17:56, 30 March 2007 (UTC)
thread_title:  POV - Prevalence 

message: What are specific methods to keep normal blood glucose levels low, (glycosylated hemoglobin, also called HbA1c, values < 5.0)? —The preceding unsigned comment was added by 129.137.155.162 (talk) 05:42, 12 April 2007 (UTC)
replies: text: I am not sure this is in scope of the article OR WP. I think seeking serious medical advice is a better strategy. BeingObjective (talk) 21:10, 24 October 2023 (UTC)
thread_title:  How to keep normal blood glucose levels low? 

message: Ornish Esselstyn and Gould have succeeded in regressing atheroma in most of their patients. Should not this be mentioned? robert2957 (talk) 14:41, 23 November 2007 (UTC)
replies: text: I also think this is worth a mention.  I don't know Gould's work, but a one line summary of the other two would be that Ornish proved that lifestyle changes (diet, relaxation, exercise...) can reverse cardiovascular disease and Esselstyn later proved that it was the dietary changes which got the job done (avoid all animal products and refined oils, eat cruciferous veg multiple times a day). Great floors (talk) 00:59, 20 January 2017 (UTC)
replies: text: Very little real data on this - diets and reversal of CAD - weak evidence. BeingObjective (talk) 21:11, 24 October 2023 (UTC)
thread_title:  Esselstyn Ornish And Gould

message: re my edit - I've removed capitalised case to sentance case, also had unwheldy long titles - so I've shortened and drifted them somewhat closer to common section name style per WP:MEDMOS. David Ruben  Talk  10:13, 29 November 2008 (UTC)
thread_title: Section names

message: I can't help but wonder where did most of the information in this article originate. The references don't lead me to an abstract/synopsis about atheromas. I do believe the article is a good read, but the original source would be great to have, as I'm interested in the material.
I agree; especially the info regarding the statement atheroma's only marginally decrease the lumen size of the blood vessels they inhabit as this goes against a lot of what I have been taught (I possess a biology degree and now study medicine) and is not referenced. I have asked my lecturer and will modify the article when and if necessary.  —Preceding unsigned comment added by 90.207.164.231 (talk) 01:35, 10 April 2009 (UTC)
thread_title: References?

message: "Pathogenesis of Acute MI" - links to the pri-med website.  I can't find the discussed video even searching for it.  Remove? AndyDScott (talk) 12:17, 30 June 2010 (UTC)
replies: text: I just removed it; thanks for checking on that. -- Beland (talk) 17:04, 27 April 2015 (UTC)
thread_title: Link to pri-med

message: The scientific consensus is that there is a causal link between cholesterol and atheroma. There are good references in the lipid hypothesis article if anyone wishes to examine them. So, unless the claim that there is no connection between cholesterol and atheroma is given a good citation soon I am going to remove it.27.33.62.77 (talk) 05:11, 22 July 2010 (UTC)
replies: text: Far more complicated - many MIs occur in folks with good SChol levels. Statins really cause plaques to be more stable - and this is a big deal - so it is not just published 'good' serum cholesterol values.  BeingObjective (talk) 21:16, 24 October 2023 (UTC)
thread_title:  Cholesterol 

message: I suggest this information is too detailed for this page and this section should be abbreviated or incorporated into the body text and additional material merged with the page on Intima-media thickness. Adh (talk) 18:12, 16 April 2012 (UTC)
replies: text: Agreed; I added a merge tag on both articles. -- Beland (talk) 17:06, 27 April 2015 (UTC)
thread_title:  IMT measurements in the carotid artery 

message: This is located in Vulnerable plaque. Perhaps it should be shifted here 129.180.1.224 (talk) 06:43, 8 June 2013 (UTC)
replies: text: Agreed; it seems like that article should be merged into this one.  I added merge tags on both. -- Beland (talk) 17:15, 27 April 2015 (UTC)

text: Agree - some redundancy between articles. should be merged. BakerStMD 16:09, 22 May 2015 (UTC)
thread_title:  Mechanism of atheroma formation 

message: I am removing unsubstantiated claims (bolded) from this paragraph:
Most artery flow-disrupting events occur at locations with less than 50% lumen narrowing. From clinical studies published in the late 1990s to  IVUS (in-the-artery-ultrasound) to visualize disease status, the typical heart attack occurs at locations with about 20% stenosis (narrowing), prior to sudden lumen closure and resulting myocardial infarction. Cardiac stress testing, traditionally the most commonly performed noninvasive testing method for blood flow limitations, generally only detects lumen narrowing of ~75% or greater, although some physicians advocate  nuclear stress methods that can sometimes detect as little as 50%.
Justification: Whether most ACSs arise at locations with mild or severe stenosis is a somewhat contentious issue in cardiology (see this article for both sides of the issue), but not even the "mild stenosis" side (which I believe is in the minority) says that the typical MI is caused by a 20% stenosis. The paragraph gave no references for its bold claims. There have been studies in the 1990s that seemed to show mild stenoses were responsible for most ACSs, but the degree of stenosis was checked a long time before the actual ACS. I believe it is best to refrain from taking sides until there is consensus. See also this article by William Fearon.
89.72.197.53 (talk) 08:55, 24 February 2016 (UTC)
replies: text: I'd check that as of 2023 - lumen blockage of 90 percent in the LAD - can have no clinical symptoms - until the big MI occurs! BeingObjective (talk) 21:18, 24 October 2023 (UTC)
thread_title:  Typical heart attack occurs at 20% stenotic arteries? 

message: The introduction of the article says "Veins do not develop atheromata, because they are not subjected to the same hemodynamic pressure that arteries are".
Mechanically speaking, that doesn't make any sense. Atheroma shouldn't "accumulate" in the arteries because the hemodynamic pressure is higher. Just like deposits will be less likely to accumulate in a pipe where the dynamic pressure is the highest.
The cited ref () says "The present experiment showed that the wall thickness of GCCA (arteries, used as veins in the study) decreased continuously and possessed similar structures as that of veins 12 weeks post surgery".
So it really doesn't seem like a mechanical accumulation of sand, but more like the targeted patching of wall weaknesses. Patches that are no longer necessary and thus are removed when the artery is used as a vein. How many years will we have to wait for that kind of "groundbreaking discovery" from the medical community? The RedBurn (ϕ) 13:19, 28 March 2017 (UTC)
thread_title:  Why does atheroma develop only in arteries and why does it accumulate even though the hemodynamic pressure is higher? 

message: The first line of this section starts "Yet not in yield to despite these medical advances"
Does this mean anything?  If it does can it be expressed more clearly?94.196.226.111 (talk) 12:49, 17 September 2017 (UTC)
thread_title:  History of Research, paragraph 5, line 1 

message: I suggest to reword the current  section and remove statements lacking sources. --AXONOV (talk) ⚑ 09:35, 22 April 2021 (UTC)
thread_title:  Treatment section 

message: Hi! I'm new to Wikipedia editing.
For this section- would these 3 sources be appropriate to use (file:///C:/Users/oyeyo/AppData/Local/Temp/MicrosoftEdgeDownloads/0d48096a-c5bf-4175-94d3-9df86e0de4f8/ATHEROMA_PREVENTION_AND_TREATMENT.pdf  AND/OR https://www.belmarrahealth.com/atheroma-causes-symptoms-prevention/ AND/OR https://www.health.harvard.edu/cholesterol/atherosclerosis-symptoms-and-treatments)?  If anyone can kindly confirm this pls?
Thanks! Oluwa24 (talk) 20:22, 29 May 2022 (UTC)
thread_title: Treatment section

message: The caption of the second picture reads:
: Narrowed arterial blood vessel blocked with an atheroma (artist's conception).
However, that caption as well as the picture itself is exactly the opposite of what the rest of the article says:
: because arteries enlarge, not constrict, in response to increasing atheroma.
: Atheroma and changes in the artery wall usually result in small aneurysms (enlargements) just large enough to compensate for the extra wall thickness with no change in the lumen diameter.
So this picture is highly misleading and needs to be removed. However, I am in no way a medical expert, so I will only do this if nobody responds to me here. Eheran (talk) 12:16, 22 December 2023 (UTC)
thread_title:  Misleading picture?