Talk:Afferent nerve fiber

message: I'm concerned about the figure, which seems to suggest that sensory neurons from the skin typically terminate in the spinal column.  As far as I am aware, the vast majority project to the brain, with the first connection occurring in the cuneate nucleus. 82.230.75.45 21:36, 11 July 2016 (UTC)
replies: text: I'm having a hard time getting a few things straight, concerning the nature of what makes up the body of afferent (sensory) nerves. The current text of this page says: "The structure of an afferent neuron contains a single long dendrite and a short axon". Presumably, this refers to a neuron the body of which is in the dorsal root ganglion. So presumably the nerve that carries the sensory signals from the skin, for instance, towards the spine is a bundle of those long dendrites. Is that right? That seems strange to me, not least because elsewhere it says that neurons have myelin sheaths around their axons - and doesn't mention the dendrites. I have seen no mention anywhere of myelin around dendrites. So if the afferent nerves are a bundle of dendrites, that means they have no myelin? But since myelin is there to speed up the impulses, doesn't that make afferent nerves slow? Otherwise, if the afferent nerves are bundles of axons, where are the neuron bodies? If they are in the dorsal ganglions, that would mean that the signal travels 'down' the axon, 'towards' the cell bodies... But that seems impossible. The other possible answer would be for the neuron bodies to be in the skin. But I don't see any references that say that. So I'm baffled. Could some one clear that up for me (and in the articles)? David Olivier 22:59, 28 June 2007 (UTC)
thread_title:  Single long dendrite? 

message: This publication gives insight on how non-peptidergic primary afferent neurons are involved in pain signaling: Saeed and Ribeiro-da-Silva Molecular Pain 2012, 8:64
Pain-related (nociceptive) information is carried from the periphery to the dorsal horn of the spinal
cord mostly by two populations of small diameter primary afferents, the peptidergic and the non-peptidergic. The
peptidergic population expresses neuropeptides, such as substance P and calcitonin gene-related peptide, while
the non-peptidergic fibers are devoid of neuropeptides, express the purinergic receptor P2X3, and bind the
isolectin B4.
Pshuster (talk) 16:30, 16 December 2012 (UTC)
thread_title:  Pain and Afferent Nerves 

message: "The majority of these are unipolar neurons in that they have a single axon leaving the cell body and is sent towards the sensory organ." Don't most sorts of neurons have a single axon? Should it say "a single neurite"?  Also "and is sent towards the sensory organ" is poor English. Better would be a new sentence "This axon/neurite extends towards the sensory organ". Also the paragraph before the one with this sentence says that afferent neurons are pseudounipolar, which agrees with the illustration. So which is it? Theodore.norvell (talk) 16:12, 11 November 2013 (UTC)
thread_title:  Single Axon 

message: Would this not be better at Sensory nerve fiber? Is "afferent" somehow more precise?LeadSongDog come howl! 13:17, 8 April 2014 (UTC)
thread_title:  Move? 

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