Talk:Tributyltin

message: Fleshed out the Introduction to give a more comprehensive overview of TBT's use, toxicity and current status  
*included that TBT is used in anti-fouling paints (bottom paint) and explained its function. In response to suggestions to add more desciptions.
*kept name of organizations that banned TBT (against suggestions of peer review)
*added where it was still a problem
Chemical Properties
*added chembox to include a lot of technical info about TBT, so we could talk about more environmentally relevant details in the chemical properties 
*added details on half life and sedimentation
*decided that blending chem properties and uses was not a good idea, against peer review suggestion
* moved the chemical lab use from uses to chem properties 
Uses
*added more details about how biocide functions, and why TBT is used in anti-fouling paint
*emphasized that anit-fouling paint comes into contact with water
*expanded on mechanism/how it works
Toxicity
*more details on half-life
*molecular details on invert toxicity
*focused on a more studied and more effected organism
*added more details on Tuna contamination as indication of TBT spread through the food chain globally
*cleared up some confusion about molecular targets in vert
*Seperated a mammals section 
*explain why hearing loss is a major problem for marine ecosystems
Regulation
*organized regulation more chronologically
*added cost/financial issues
*expanded on what the IMO regulation entailed more specifically
General Edits
*fixed grammatical errors, made writing flow more
*changed diction to make more formal/professional
HallCU (talk) 01:27, 29 April 2014 (UTC)
thread_title: Response to Peer Revision

message: Wikireview: Tributyltin
Overview:
Good Start! It is really difficult to sum up all the parts of the article in only a few sentences! I feel like you should add that tributyltin compounds are mainly used on boats. I think by including a practical application it makes the complicated chemical name seem more grounded, which is important for an overview. Also, I don’t know if you need to include the organization names that have banned TBT because they are really long and you could just say that they have been banned by various “regulatory organizations.” I think it is okay to be general in the overview and then add details later when you talk about policy.
TBT Chemical Properties:
You could probably change the title to “chemical properties”  and take out the TBT because we know its about TBT, but it’s a minor detail. Overall I think this paragraph is well written.
Uses: 
I’m not sure whether anti-fouling should be hyphenated or not? You could also include that antifouling paint is also called bottom paint. It I think it would be beneficial to have a link to “antifouling paint” because there is a Wikipedia page for it. It might also be helpful to take a sentence to explain what it is because I didn’t know what it was. I would emphasize that anti-fouling paint is primarily used on boats, which come into direct contact with the marine environment. I think the last sentence “In the chemical laboratory, tributyltin hydride generated by the action of lithium aluminium hydrideon tributyltin chloride is used to replace halogens in organic compounds for hydrogen” is more applicable to the chemical properties section. Even though it is technically a use of TBT, you don’t really talk about any other chemistry in the “Uses” section so I think it would fit better in the “Chemical Properties” section where you describe the structure.
Toxicity:
You first sentence was wordy so I re-structured it a little. I think that you could break this section up into 2 paragraphs. I think the information about it accumulating in sediment can be a separate topic from the toxic effects. The first paragraph could explain why its bad and the second could say why we should still care about it. It is easier to read shorter paragraphs.
Marine Invertebrates:
“Chironomus riparious” should be italicized because it is a species name. You could also include that it is a type of mosquito and is used in toxicology tests because it is easy to study the development in early embryos. Also a wikilink to the page for chironomus riparious would be helpful. It would make the article more readable for people outside the scientific community. Also explain what benthic invertebrates are. This is not something everyone would know and it is important information to understand the data because these organisms are found in the sediment at the bottom of bodies of water. It makes sense that they would be affected by TBT, which accumulates in the sediment. Also italicize and wikilink “Lymnaea stagnalis” in the second paragraph.
Marine Mammals:
Also italicize, link, and include the common names of the organisms that you talk about. I think something got cut off at the end of your first paragraph when you talk about tail abnormalities. I don’t think you need to include the full name of the enzyme “11beta-hydroxysteroiddehydrogenase type 2.” I would be sufficient to say that it inhibits the activity of the enzyme that converts cortisol to cortisone. You could also give a brief explanation of the purpose of glucocorticoid. It is confusing because it sounds like glucocorticoid is related to the genes that cause the growth of fat cells, but I’m pretty sure it regulates the levels of glucose in response to stress. In the third paragraph, I think it would read better if you said the otters have “higher tissue levels of butyltins” instead of “higher level of tissue butyltins.” When you talk about the hearing loss in whales, I think it would be more affective to explain why it matters. I know that hearing loss for dolphins is a huge issue because they use echolocation to hunt, and they communicate in some ways through sound. I would assume that whales would be affected in a similar way. A lot of people might assume that hearing loss for aquatic organisms is not important because they are under water.
Past and Current Responses:
Capitalize the entire title. A more accurate title might be “Past and Current Regulation and Policy.” In the first sentence I think you need to say “the use of organotin compounds” and instead of “has been banned” you can say “was banned.” 
Juli12Anne (talk) 03:48, 11 April 2014 (UTC)
thread_title: Peer Revision

message: Trybutyltin
1) TBT chemical properties - discuss in more detail than already on the page, and link more directly to Organotin Compounds Page. 
	
2) Uses of Trybutyltin
Justifications for its use in industry
ex. marine anti-fouling paint, ensures good fuel efficiency, less ship repair
molluscivide
stone preservation
wood preservation
	
This also gets into how its released into the environment - boats in particular
3) Repercussion
(possibly talk about how TBT is moved around in the marine environment- ex. Volatilisation, Photolysis, Adsorption)
B) Biological 
invertebrates
ex. shell defomrations in oysters
masculinization of femal marine snails
Imposex
vertebrates
ex. immunosupression in otters and dolphins
	links to obesity 
bacteria - evidence of resistant bacteria 
C) Molecular
	depending on the amount of information we can dig up, we  can dicuss known molecular processes that lead to these deformities, and focus on targets of TBT common mechanism   
How it is metabolized that
This should relate to the Tin Poisining Page, and we will make links to the page
3) Political Response
many countries have taken steps to regulate TBT
	registered as pesticide
	limiting content in paint
	limiting sale
controversial however, bc of effect on industry prices.
EPA policies 
Tin Poisoning
After getting more details from TBT and linking them to this page, we canput more emphasis on 
1) Treatment
2) Related Diseases 
References
Westrum, Bente; Thomassen, Yngvar (2002). The Nordic Expert Group for Criteria Documentation of Health Risks from Chemicals and the Dutch Expert Committee on Occupational Standards : 130. Tin and inorganic tin compounds. Arbetslivsinstitutet.
Mora, Stephen (1996) Tributyltin: a case study of an environmental contaminant. Cambridge envorinmental chemistry series 8. 
Chemical Database http://extoxnet.orst.edu/pips/tributyl.htm
EPA standards for TBT 
http://water.epa.gov/scitech/swguidance/standards/criteria/aqlife/tributyltin/fs-final.cfm
TBT linked to obesitiy 
Zylius, Steve (2013) Fetal exposure to tributyltin linked to obesity in offspring and subsequent generations. UCIrvineNews
http://news.uci.edu/press-releases/fetal-exposure-to-pvc-plastic-chemical-linked-to-obesity-in
Pitpeelorchard (talk) 18:28, 26 February 2014 (UTC)
thread_title: Outline for Revision

message: What about moving this article to Tin poisoning.  Most of the concerns with tin toxicity are related to triorgano- and diorganotin compounds.--Smokefoot (talk) 23:22, 7 May 2011 (UTC)
thread_title: Page should be merged or revised strongly

message: I dont think that a lot of editors are watching this thing, but the article is about a topical issue in antifouling paints.  The title should probably reflect that.  The term "tributyltin" is environmental jargon, and would bother chemists since it is almost a meaningless adjective.  Possible names = Environmental effects of organotin compounds, etc--Smokefoot (talk) 14:10, 28 December 2014 (UTC)
replies: text: Maybe… If "tributyltin" is, as you say, the common environmental jargon for all this then it might make sense to keep with the current title. After all tributyltin doesn't exist as a discreet chemical (assuming that bis(tributyltin) doesn’t count) so this page isn’t really getting in the way of anything. That’s just me though, I prefer short page names - readers can be lazy when entering search terms. --Project Osprey (talk) 10:03, 3 February 2015 (UTC)
thread_title: Propose to rename this article

message: Overall, I think this article is well put together, but I think some sections could stand to be expanded a bit, if data exists to expand them.
Specifically, I think the first two paragraphs of the Toxicity section would benefit from expansion. In the first paragraph, it seems like it would be useful to know the actual physiological effects that it is having on the organisms it is poisoning, as well as how, specifically, it "harmfully effects many layers of the ecosystem" and what exact layers are being effected and how. It would be also be useful to have some specific numbers with regards to its accumulation in sediment, and the actual levels found in the sediment.
--AELie515 (talk) 03:08, 2 February 2015 (UTC)
replies: text: Be sure to adhere to WP:MEDRS and WP:SECONDARY: cite real books and reviews.  If you are not expert on relevant chemistry or toxicology, then be cautious in your editing.--Smokefoot (talk) 14:27, 2 February 2015 (UTC)
thread_title:  Edit Suggestion 

message: I think this is a very concise and knowledge page.  My main concern is the contradiction found within the invertebrates section.  It shows biologically and experimentally how TBT causes masculinization in invertebrates.  In the following paragraph, it states how  in chironomus riparius, another model invertebrate, produces the exact opposite result of showing feminization.
Tracklete14 (talk) 04:30, 3 February 2015 (UTC)
replies: text: Well they are very different organisms, one is a snail and the other a fly. I'm willing to beielve that they both suffer reproductive effects from TBT but that the outcomes are different (You've only got two possible outcomes). I've added some refs to try and clear that up but we need a good secondary review to work from if we're going to make a good job of this. --Project Osprey (talk) 10:24, 3 February 2015 (UTC)
thread_title:  Edit Suggestion 2 

message: I changed a number of expressions of fractions of the form ng l-1 to use the solidus (/): ng/l. Customary practice of typography favors the solidus for in-line math, as in this case. I hope this edit is OK.  — Preceding unsigned comment added by ArthurOgawa (talk • contribs) 17:16, 16 June 2015 (UTC)
thread_title:  Edited math expressions 

message: Substituted at 09:15, 30 April 2016 (UTC)
thread_title: Assessment comment

message: Hello fellow Wikipedians,
I have just modified  on Tributyltin. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
*Added archive http://web.archive.org/web/20071217113821/http://www.ncl.ac.uk:80/barnacles/ to http://www.ncl.ac.uk/barnacles
*Added archive http://web.archive.org/web/20081106130922/http://www.epa.gov/waterscience/criteria/tributyltin/tbt-final.pdf to http://www.epa.gov/waterscience/criteria/tributyltin/tbt-final.pdf
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thread_title:  External links modified 

message: According to Chemical Abstracts, for "tributyltin": 15,755 reports have been published, of which 306 reviews have appeared since the year 2000.  Wikipedia editors should show preference for reviews per WP:SECONDARY and for books WP:TERTIARY, but instead recent editors are contributing primary literature.  What is the plan? Add cite all 15,755 papers? The top cited reviews are not mentioned in this article:
#Antifouling technology-past, present and future steps towards efficient and environmentally friendly antifouling coatings
Quick View  Other Sources
By Yebra, Diego Meseguer; Kiil, Soren; Dam-Johansen, Kim
From Progress in Organic Coatings (2004), 50(2), 75-104.  |  Language: English, Database: CAPLUS
#Organotin compounds in the environment - an overview
Quick View  Other Sources
By Hoch, M.
From Applied Geochemistry (2001), 16(7-8), 719-743.  |  Language: English, Database: CAPLUS
#Health effects of endocrine-disrupting chemicals on wildlife, with special reference to the European situation
Quick View  Other Sources
By Vos, Joseph G.; Dybing, Erik; Greim, Helmut A.; Ladefoged, Ole; Lambre, Claude; Tarazona, Jose V.; Brandt, Ingvar; Vethaak, A. Dick
From Critical Reviews in Toxicology (2000), 30(1), 71-133.  |  Language: English, Database: CAPLUS
#Modern approaches to marine antifouling coatings
Quick View  Other Sources
By Chambers, L. D.; Stokes, K. R.; Walsh, F. C.; Wood, R. J. K.
From Surface and Coatings Technology (2006), 201(6), 3642-3652.  |  Language: English, Database: CAPLUS
Here is what should be done: replace all primary literature with reviews.  Wikipedia is an encyclopedia, not a compendium.--Smokefoot (talk) 12:31, 18 September 2020 (UTC)
replies: text: I agree 100%. However, as do not have access to the literature, I cannot offer to help. Yilloslime (talk) 18:05, 18 September 2020 (UTC)
thread_title: 15000 papers and counting

message: Log Kow is unitless. It is incorrect and confusing for the talk of log Kow to be followed by the solubility of TBT, which is a completely different quantity Science Is My Life (talk) 07:58, 3 July 2021 (UTC)
thread_title:  Log Kow 

message: — Assignment last updated by Chazzidy Harper (talk) 18:02, 28 September 2022 (UTC)
thread_title: Wiki Education assignment: Toxicology

message: https://en.wikipedia.org/wiki/User:HL02378/Tributyltin/Bibliography?preload=Template%3ADashboard.wikiedu.org_bibliography HL02378 (talk) 20:26, 28 September 2022 (UTC)
thread_title:  Bibliography: Possible Sources to add into the article