Talk:Neurodegeneration

message: User 202.7.77.248, if I understand you correctly, you are saying that there is evidence that chronic depression can, in some cases, be caused by the presence of "glial reduction in the subgenual prefrontal cortex."  That finding, however, does not allow us to conclude that depression is always caused by this condition.  Nor can we conclude that the glial reduction is the result of disease, nor that it is degenerative.  Or am I missing something?
Öngür*, Drevets, and Price state in the conclusion to their study: "We thus have identified a biological marker associated with familial mood disorders that may provide important clues regarding the pathogenesis of these common psychiatric conditions."  Clues only.  Not facts.  Sunray 08:30, 3 November 2005 (UTC)
replies: text: Thanks for contributing to the debate - true - these are clues - however important ones and possible implications should be carefully cosidered before early withdrawel of medication when patients with chronic depression seems better - further studies in risktaking behaviour for this patient group is necessary. .
Pjr05, you really need to look into Wikipedia's guidelines for content. Let's start with NPOV. There is a strong precedent that tentative, speculative and otherwise not widely accepted views only need a forum in Wikipedia if they have a large support base. For example, if a significant portion of neurologists or psychiatrists believes that depression may have a neurodegenerative component, then this would require mention both here and on clinical depression. Unfortunately, you have presented no evidence that this is the case; it may be a matter of your personal conviction or even a few people, but that does not make it worthy of inclusion in an encyclopedia.
Please understand that we are not here to censor or suppress information, but like any encyclopedia we need to be careful that what we're presenting actually consists of accepted views. Further studies may lead to the material becoming worthy of inclusion at some point in the future. I hope you understand these considerations, and I also hope this will not deter you from contributing to this project in other ways. JFW | T@lk 14:22, 3 November 2005 (UTC)

text: Dr Wolff - Point taken - thanks for constructive appraoch - I believe there is constructive evidence (animal and human studies - Yale and Wisconson) that demonstrate this - I will endevour to present some of the research - may be in a stub re "research on links between depression and neurodegenerative disease" Peter 
Considering the study was performed in 1998, have any other studies been undertaken to validate its findings? JFW | T@lk 22:12, 3 November 2005 (UTC)
thread_title: Chronic depression as a neurodegenerative disease

message: I know nothing at all about neurology, so I'll only make a suggestion and let others decide.  Should Shy-Drager syndrome be included in the list of neurodegenerative diseases?  By chance, I noticed that the Johnny Cash article links to Shy-Drager and describes that syndrom as neurodegenerative. Hult041956 22:31, 17 August 2007 (UTC)
thread_title:  Add Shy-Drager syndrome? 

message: MS has been proven to be an autoimmune disease, thus in medical terms neurodegenerative no longer fits it (the term usually applies to auto-degenerative, loss due to external reasons, like inner skull pressure isn't considered neurodegenerative). as for  FTLD, please see http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600274  —Preceding unsigned comment added by 217.132.28.7 (talk) 17:52, 31 August 2008 (UTC)
thread_title:  removed multiple sclerosis, added Frontotemporal lobar degeneration 

message: Following discussion at WT:WikiProject Neuroscience, I have redirected this page to Neurodegeneration, which is a substantially stronger article.  If anybody has comments or objections, could you please present them at the discussion there? Looie496 (talk) 19:14, 1 February 2010 (UTC)
thread_title:  redirect 

message: There is a move discussion in progress on Talk:Neurodegeneration which affects this page. Please participate on that page and not in this talk page section. Thank you.  —RMCD bot 18:18, 14 December 2021 (UTC)
thread_title:  Move discussion in progress