Talk:Diclofenac

message: 3D structures are derived, and should not appear without details of the source of the 3D structure coordinates, or, minimally, of the computations performed to generate the 3D structures from the 2D map of atoms and connectivities (line angle structure, as shown in infobox). Otherwise such 3D structures are unsourced WP:OR. This spinning 3D structure — with its inexplicably determined dihedral and bond angles — is such a case of unpublished, and undocumented original research. As well, it presents the carboxylic acid (protio) form of the compound, when the title compound is almost inevitably a salt form.   Le Prof 71.239.87.100 (talk) 01:44, 8 September 2014 (UTC)
thread_title:  Removal of 3D animation 

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thread_title:  External links modified 

message: * Popular painkiller linked to cardiac risk Axylus.arisbe (talk) 10:15, 10 September 2018 (UTC)
thread_title:  Cosmos magazine: associated with 50% hike in heart risk compared to non-users. 

message: introduced as Voltaren by Ciba-Geigy (now Novartis) in 1973, now ?!? by Glaxo SmithKline.[51]
--Maxus96 (talk) 18:31, 11 July 2019 (UTC)
thread_title:  missing verb 

message: Diclofenac was patented in 1965 by Ciba-Geigy
Don't see how this is possible as CIBA-Geigy did not exist in 1965. CIBA (acronym for Chemical Industries Basle should be in capital letters) CIBA and Geigy merged in 1970. I was there.
2601:18E:C401:D060:1DF4:35FD:FA93:5E7E (talk) 17:38, 27 May 2020 (UTC)
replies: text: Good point. I suppose if the above information is correct then one has to find out which of the two had the (original) patent. (We can probably assume that the patent was transferred into CIBA-Geigy in 1970). 2A02:8388:1641:8380:1535:595B:9280:DF61 (talk) 04:08, 8 June 2020 (UTC)
thread_title:  diclofenac 

message: I used this citation: https://www.youdrugstore.com/health/voltaren-gel-usage.html
If this citation isn't good enough, please let me know why and ping me so i see your reply.--Hiveir (talk) 19:43, 1 June 2020 (UTC)
replies: text: The above looks like advertisement to me. If it is I would recommend to remove such links. 2A02:8388:1641:8380:1535:595B:9280:DF61 (talk) 04:09, 8 June 2020 (UTC)
thread_title:  Onset time gel 

message: It would be nice if there could be a subsection on the main article how diclofenac interacts with its target protein. The reason why this should be mentioned, IMO, is firstly because it is a small drug, second, it was historically important, but third and most importantly, there are .pdb structures showing it in a complex such as 1NR6.pdb, so it has a role that was already described (and can be studied in e. g. PyMOL or similar software suites). 2A02:8388:1641:8380:1535:595B:9280:DF61 (talk) 04:07, 8 June 2020 (UTC)
thread_title:  Molecular Interactions 

message: A discussion is taking place to address the redirect :Dichronic. The discussion will occur at Wikipedia:Redirects for discussion/Log/2021 March 3#Dichronic until a consensus is reached, and readers of this page are welcome to contribute to the discussion.  Shhhnotsoloud (talk) 17:20, 3 March 2021 (UTC)
thread_title:  "Dichronic" listed at [[Wikipedia:Redirects for discussion|Redirects for discussion]] 

message: Diclofenac is available in a lot more formulations than just Voltaren.  There are eye drops, gels etc.  I'm not expert enough to change the article.  But someone should have a look at it and include the broader picture. BTW it's not just for humans, but also used in vetarinary medicine.2600:1700:1C64:8240:444B:CD9C:89C5:CAB (talk) 2600:1700:1C64:8240:444B:CD9C:89C5:CAB (talk) 02:44, 31 October 2022 (UTC)
thread_title:  Too limited in the application described