Talk:Pyrroloquinoline quinone

message: Nunh-huh, did you not read their FAQ, or do you have new information?
"At the molecular level, PQQ is involved in the lysine degradation. We have found a gene for PQQ-dependent enzyme from human as well as from mouse. So, PQQ is also essential to humans."
Yggdræsil 07:14, 27 April 2004‎ ‎ 
I edited the page by removing the "not a vitamin" sentence as it has positively been identified as a vitamin from what I've read.
24.83.178.11 09:06, 9 January 2007 (UTC)
thread_title:  Edits 

message: If PQQ is SUSPECTED to not be a vitamin, then the article should reflect it. i.e. the research saying it is a vitamin and the counter research should both be mentioned since nothing has been proven definitely.24.83.148.131 (talk) 08:48, 10 April 2008 (UTC)
thread_title: PQQ Not A Vitamin Maybe?

message: Since it may be a vitamin it would be useful for article to list some food sources for it ? - Rod57 (talk) 02:48, 5 February 2012 (UTC)
replies: text: FWIW, foods contain it in very negligible quantities when compared to 10-20 mg supplements. The research and the effects are in no way comparable. --IO Device (talk) 14:37, 30 December 2014 (UTC)
replies: text:  Since it is sold as a dietary supplement, what is known about its digestion, absorption and consumption/excretion ? - Rod57 (talk) 20:14, 26 February 2016 (UTC)
replies: text:  One source might be section 3 of  and its references. I am not personally inclined to get into this article, however. FeatherPluma (talk) 05:09, 6 March 2016 (UTC)
thread_title:  Which foods contain it ? 

message: This article contains back and forth arguing. Revision needed. Gary Dell'Abate (talk) 00:41, 27 January 2015 (UTC)
thread_title:  Cyclical Arguing 

message: "It is found in soil and foods such as kiwifruit, as well as human breast milk."
What are "foods such as kiwifruit"?
Drsruli (talk) 09:00, 6 December 2021 (UTC)
thread_title:  Please Explain 

message: The sentence
"An article by Bruce Ames in The Proceedings of the National Academy of Sciences in 2018 identified pyrroloquinoline quinone as a "longevity vitamin" not essential for immediate survival, but necessary for long-term health."
Should be deleted, and is outright false.
PQQ is a cofactor in dopamine synthesis and subsequent degradation to norepinephrine.  Source: BIOCHEMICAL PATHWAYS: AN ATLAS OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, John Wiley and Sons, 2012, and subsequent versions.
No dopamine or norepinephrine is incompatible with life.
Dr. Robert Zee
Engineer / Chiropractor / Biochemist / Genetic Analyst 98.62.198.136 (talk) 20:02, 10 May 2023 (UTC)
thread_title:  PQQ Role in Dopamine Synthesis 

message: The Vitamin story is currently a bit... incomplete. The introduction section of PMID 27230956 (already cited) mentions PQQ deprivation experiments, which could provide context to the notion of PQQ as a vitamin. It also mentions that the K&K 2003 vitamin notion was broken due to a wrongly assumed cofactor role for ACSF4-U26. Now that we know it really is a cofactor of something, this context might be quite relevant. PMID 30322941 (also already cited) cites PMID 19803551 for context on the debate. Artoria2e5 🌉 12:46, 12 October 2023 (UTC)
thread_title:  Vitamin story