Talk:Genetic recombination

message: Does this article, perhaps, need to be merged (or merged and re-split along better lines) with chromosomal crossover?--ES2 18:31, 24 Jul 2004 (UTC)
replies: text: This article was distinct until it was butchered on 23 July 2004. That edit eliminated the general definition of genetic recombination and reduced it to being nothing more than chromosomal crossover--which was addressed in the original article. If I weren't too busy to follow up on this right now, I'd probably revert all the way back to 23 July. AdamRetchless 04:23, 20 Jan 2005 (UTC)
replies: text: I didn't think that expanding a stub was exactly butchering the article.  Thankfully the article has gotten better since that expansion. --ES2 05:01, 26 April 2006 (UTC)
thread_title:  Merge: Recombination with crossover 

message: I have a real problem with the use of intra- vs inter-chromosomal recombination here. Ben Carritt 17:48, 23 December 2005 (UTC)
thread_title: Intra- vs inter-chromosomal recombination

message: "...in the first Santino junction..."
What is that? SamEV 10:42, 5 September 2006 (UTC)
replies: text: Mystery solved. It was vandalism, which I've just removed. SamEV 08:09, 26 February 2007 (UTC)
thread_title:  Santino junction 

message: The definition talks about two parents, and then about "asexually reproducing organisms" in evolutionary biology. Am I missing something? OK, it says that the initially given definition is not commonly used in certain fields (such as evolutionary biology), but it doesn't explain what definition is used in these fields. --194.145.161.227 17:34, 29 December 2006 (UTC)
thread_title:  Contradictory/unclear definition 

message: David Hawkins inserted the following into the main article:
:It should be noted that while a novel allele is produced in this way, no new information is being created by this process. Recombination simply rearranges existing genetic information.
This is an antievolution talking point. It comes with no substantiation whatsoever, and depends critically on leaving any coherent definition of "information" out of the discussion. While this may not meet the Wikipedia:Vandalism criteria, it comes pretty close to that. I suggest reverting to the previous version. --Wesley R. Elsberry 17:56, 5 January 2007 (UTC)
replies: text:  I would agree with your justification for removal... what is a novel allele if not new? Recombination rearranges existing genetic information to produce new combinations. The definition of "information" needs to be elucidated to return this statement to NPOV status. -- Serephine ♠ talk - 07:28, 9 January 2007 (UTC)
thread_title: Information Issue

message: The sentence
In evolutionary biology this shuffling of genes is thought to have many advantages, including that of allowing sexually reproducing organisms to avoid Muller's ratchet.  
should say asexually instread of sexually.
Bindi13 (talk) 06:51, 14 April 2008 (UTC)
replies: text: I think perhaps you are misreading it, it looks correct to me... Madeleine ✉ ✍ 13:35, 14 April 2008 (UTC)

text: Maybe the confusion arises because recombination occurs both in non-sexual context and (the vast majority) in systems that mate. Maybe recombination is here intended to refer to non-sexual recombination, as for example in bacteria. I.e. Even though asexual organisms should be prone to amass negatively affecting mutations, some types can escape by the application of exotic kinds of recombination, for example bacterial conjugation. --Ettrig (talk) 05:51, 8 February 2011 (UTC)
thread_title:  Error in first paragraph - asexually 

message: The definition of recombination used in the article - the breaking and rejoining of DNA strands to form new molecules of DNA - must be wrong. Doesn't recombination includes, in addition to croosing over and the other mechanisms cited in the article, the pairing of homologous chromosomes (and the independent assortment)? By the definition in Griffiths' Introduction to Genetic Analysis, chapter 3, recombination is production of new combinations of aleles (which is made by homologous pairing, too).
:::::Unsigned comment from IP:200.158.32.64
:You are absolutely correct. For keeping this sort of information straight, it is important not to overlook the authoritative references for definitions of terms, even if they pre-date some of the knowledge, such as Rieger, Rigomar; Michaelis, Arnd and Green, Melvin M. 1968. A glossary of genetics and cytogenetics: Classical and molecular. Springer-Verlag, New York. isbn:9780387076683
:Here are some quotes from that book:
:*"Recombination (Bridges & Morgan 1923) — any process which gives rise to cells or individuals (recombinants) associating in new ways two or more hereditary determinants (genes) by which their parents differed (⇒ genetic recombination)."
:*"Genetic recombination — in a broad sense, any process by means of which two (or more) "parents" (organisms, cells, or molecules containing ⇒ genetic information) with different genetic characters pair, interact, and give rise to progeny (recombinant individuals, cells, or molecules) so that genes in which the parents differed are associated in new combinations (e.g., from AB and ab the recombinants Ab and aB are produced). The molecular mechanism of g. r. is not yet understood. The products of g. r. (the recombinants) may be detected after meiosis (meiotic recombination), after mitosis (in the case of mitotic recombination) or after equivalent processes occurring in bacteria and during multiplication of viruses. ... " (there follows a very long discussion of different mechanisms).
:*"Assortment — in ⇒ meiosis, the normally random, in certain cases, non-random ("preferential") distribution to the cell poles of whole chromosomes (during Anaphase I) contained in pairing configurations (⇒ chromosome pairing) and of chromatids (during anaphase II) resulting in random or non-random ⇒ segregation and ⇒ genetic recombination of genes." (then two subsections, one on "Random or independent assortment" and one on "Non-random assortment".
:::::Sminthopsis84 (talk) 14:55, 18 October 2012 (UTC)
thread_title: Definition

message: Substituted at 15:55, 29 April 2016 (UTC)
thread_title: Assessment comment

message: Unfortunately, this article is not accessible to a lay audience. It would be a grand thing if someone who understands this material would completely rewrite the article in an accessible way. Strebe (talk) 16:58, 21 April 2018 (UTC)
thread_title:  Audience 

message: How does it cause variation? Sevuloni Marseu (talk) 18:51, 15 April 2021 (UTC)
thread_title:  Genetic Recombination 

message: — Assignment last updated by Nikhil venkat konagala (talk) 03:24, 26 September 2022 (UTC)
thread_title: Wiki Education assignment: Molecular Genetics

message: If an environment is created to allow Gene Recombinations , will there be any effect on non-targeted structures? Can a (possibly unnecessary) environment as such be redacted or negated promptly if there is risk of unwanted chemical interactions? 71.178.255.180 (talk) 00:44, 4 April 2023 (UTC)
thread_title:  General Gene Recombinations 

message: The lead says this
 Most recombination occurs naturally and can be classified into two types: (1) interchromosomal recombination, occurring through independent assortment of alleles whose loci are on different but homologous chromosomes (random orientation of pairs of homologous chromosomes in meiosis I); & (2) intrachromosomal recombination, occurring through crossing over.[1]
But the main text says this
 Chromosomal crossover involves recombination between the paired chromosomes inherited from each of one's parents,
Please rectify. Thanks. 2A00:23C6:54D3:DA01:E1CE:79A2:7FB2:384A (talk) 14:01, 14 May 2023 (UTC)
thread_title:  Contradiction between definitions of crossover in lead and in main text