Talk:Dermatitis herpetiformis

message: We should mention that TG3 is the autoantigen -  Epidermal Transglutaminase (TGase 3) Is the Autoantigen of Dermatitis Herpetiformis. JFW | T@lk 10:38, 21 June 2006 (UTC)
thread_title: Pathophysiology

message: Must both articles contain extensive discussion of communion being wheat bread?
Agreed - perhaps that topic can be spun off into its own article?  Steve carlson 20:18, 10 June 2007 (UTC)
thread_title: Overlap with Celiac Disease

message: Many thanks to whoever wrote this page.  I had a blistering skin condition that my doctor thought at first was an infection, then scabies, then an infection again.  I was looking for info on the web and came here via dermatitis, and instantly recognised the symptoms - "Dermatitis herpetiformis is usually extremely itchy. The vesicles or papules usually appear on the elbows, knees, back, and buttocks. In most cases, it is highly symmetric. Symptoms of dermatitis herpetiformis tend to be sporadic." - yup, that's exactly what I had.  A web search for images of "dermatitis herpetiformis" confirmed my suspicions.  I had to wait for 9 weeks to see a dermatologist before the NHS confirmed what I already knew, and I could finally start on Dapsone. Occultations 11:28, 27 August 2006 (UTC)
thread_title:  Thank you! 

message: Does anyone know the average onset of symptoms after eating a gluten product? Secondly, what are the (long-term) consequences of continually eating gluten products, besides suffering with the itchy rashes? -- MacAddct1984  00:53, 2 October 2006 (UTC)
thread_title:  Onset and consequences? 

message: There is a huge section on beer and religious issues but practically no discussion of the mechanics of the disease.  
Another article on the web states a much more complete view of the disease:
http://www.aocd.org/skin/dermatologic_diseases/dermatitis_herpeti.html
I am sorry but it looks to me (and no offense to the writer because I think the creation of these entries is a noble work) that the authour(s) didn't know a lot about how the disease works and instead wrote about the impact to their life/lives.  Personally I don't care about beer or communion in the least and suspect a lot of DH sufferers would concur.
----
While going GF does have a huge impact on an individual's lifestyle I agree that the disease itself should be address more specifically... A link could easily be used to redirect to Celiac Disease if folks wanted to know more about GF Bread and Communion. Also one of the big DH questions that's not being address is, "If my skin care product (soap, shampoo, hairspray, etc.) has wheat/gluten in it, will it exacerbate my DH?"  as well as "How long does it take for DH to clear up once I go GF?" 
--Fidissimus 04:33, 1 March 2007 (UTC)
replies: text: Coeliac disease is now a featured article. The bloated topics above have been reduced to the minumum in that article. Surely a bit of work can improve the DH article as well. I disagree with Fidissimus that we should be a FAQ for DH patients. That is one thing an encyclopedia should not endeavour to be. JFW | T@lk 22:04, 26 March 2007 (UTC)
thread_title:  This topic is balanced poorly 

message: If this page hadn't existed separately from Coeliac disease then I wouldn't have been able to work out what my blistering skin condition was.  So please don't merge it.  I don't actually know if I've got Coeliac disease, I've never had any gastrointestinal symptoms.  Only about 1% of coeliacs get DH, and about 1% of people get Coeliac disease.  So merging Dermatitis herpetiformis with Coeliac disease makes as much sense as merging Coeliac disease with illness. Occultations (talk) 23:46, 27 December 2007 (UTC)
thread_title:  I vote against merging with Coeliac disease 

message: I have fought with this disease for the past year without knowing what was wrong. My primary care physician treated me for scabies (never had it), various skin conditions and finally suggested a neurosis causing me to scratch! Just last week I went to a dermatologist on referral (required for insurance coverage)  and found out I have Dermatitis herpetiformis. Until researching DH I had not heard of coeliac disease -- my Drs have not mentioned it to me at all!  —Preceding unsigned comment added by 64.39.1.11 (talk) 21:34, 1 March 2008 (UTC)
thread_title:  Do not merge with Coeliac disease, seconded 

message: DH is a separate disease. its pathophysiology may work via the mechanism of coeliac disease, which is an aberrant reaction to gliaden, involving IgA immunopathy. However, patients with DH may well be sub-clinical w.r.t. CD, or not have it at all. Medical encyclopedia at medlineplus states "The cause is unknown. However, dermatitis herpetiformis is frequently linked to gluten sensitivity", written by a doctor of dermatlogy and has been peer reviewed, ie. the two diseases are separate. Furthermore, CD does not necessarily give rise to DH. Since patients can present with symptoms of either DH or CD totally separately, I think it warrants two separate wikipedia entries. 
Previous discussion of this do make valid points, but some are presenting anecdotal evidence for their opinions. "I have DH and DO NOT have celiac" could describe a bullous disorder, unspecified (ICD-10 L13.9), which is clinically and histologically very similar to DH, but not actually the same.
thanks for reading forgetful (talk) 14:40, 13 June 2008 (UTC)
thread_title:  do not merge with coeliac disease - discussion 

message: Pdeitiker (talk) 14:51, 14 June 2008 (UTC)
thread_title:  Against merge 

message: There are some comments above about "extensive discussion of communion being wheat bread" and "huge section on beer and religious issues".  Those issues are nothing to do with Dermatitis herpetiformis as such, they are related to having to follow a gluten-free diet.  They should therefore be moved/merged to Gluten-free diet. Occultations (talk) 15:25, 14 January 2008 (UTC)
thread_title:  Move some of this to Gluten-free diet 

message: Despite the link with gluten enteropathy, DH does not lead to small intestinal lymphoma, fracture and other typical coeliac complications: http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2036.2008.03660.x JFW | T@lk 01:35, 28 February 2008 (UTC)
thread_title:  Prognosis 

message: While I am currently working through some other pages I am going to begin major alterations of this page, since
few have decided to take this on. Note, I am not targeting FA or GA status with these changes, those refinements can be made after imbalances in the article are corrected, I am not a librarian or an english major, so. . . . PB666 yap 14:09, 12 July 2008 (UTC)
thread_title: Major alterations of the Page

message: Can someone put a quick etymology up? I'm no pro, but I'm guessing this means "inflammed skin that looks like herpes."
:Right off the top of my head dermatitis = skin disease, herpetiformis = reptilian (or snake) form. The snake skin pattern comes from the pattern of inflammation that first appears and is later shown by red dots on the intersections.PB666 yap 16:23, 12 July 2008 (UTC)
replies: text: Please ask questions at the end of the page, please use ~~~~ after comments so that we know when the question was asked.PB666 yap 16:23, 12 July 2008 (UTC)
thread_title: Etymology

message: This article was listed at Wikipedia:Copyright problems/2008 July 28/Articles as a suspected copyright infringement of this source. Unfortunately, the copyright violation was substantiated. The material was introduced in 2005 by an IP editor all at one time, when the article was only a stub. All subsequent edits to the article have incorporated these substantial copyright violations. As no one had taken the opportunity provided in the seven day window to write a copyright-violation, GFDL-violation free version in article subspace as the template suggests, the copyright-infringing versions of the article have been deleted and the versions of the article prior to the introduction of the violation have been restored. I have also added in as many of the non-GFDL violating improvements as I could see that related to the existing content. If contributors to this article would like access to the existing content in order to rewrite it completely, it can be provided for that purpose. However, any version so produced can neither incorporate the existing infringement or the language of good faith contributors to the article, as the lack of attribution of these contributors is problematic. It would have to be rewritten from scratch. --Moonriddengirl (talk) 00:40, 5 August 2008 (UTC)
replies: text: Wow that sucks. It was very useful to people like me with this condition when it was up too. (MGoers37 (talk) 00:14, 18 September 2008 (UTC)
thread_title: Copyright problem

message: I have fixed some inaccuracies that have crept in.  And I've changed some things back for the following reasons:
*"The blisters vary in size from very small up to 1 cm across." - moved this back to the paragraph that first mentions the blisters, rather than one that talks about the itching or burning sensations that might or might not occur. 
*Changed the link from Linear IgA bullous dermatosis back to Adult linear IgA disease, because everything on the Linear IgA bullous dermatosis page is not relevant, apart from the link to Adult linear IgA disease. 
*Changed the capitalisation of "Dapsone" back to "dapsone", except at the start of a sentence.  This seems to be standard practice with drug names (see, for example, the Dapsone page). 
*Changed "Dapsone treatment has no effect on gluten sensitivity" to "dapsone treatment has no effect on intestinal damage", because the point is that a gluten-free diet does correct the intestinal damage.  I have avoided enteropathy because that link wasn't helpful.  The link I've given is to coeliac disease, because the picture there of the villi is exactly what's needed to illustrate the damage.
Occultations (talk) 12:44, 12 August 2009 (UTC)
thread_title:  Various small changes 

message: This article as is..>  dermatitis herpetiformis .... the rash which looks like excema because it weeps inflames a couple hours to the worst of it 10 -12 hrs after eating gluten or wheat. This rash can be on the folds of the skin anywhere .. on the back of the neck around mouth in folds of skin on face, ( corner nose.. inbetween brows around hairline in folds of smile lines and under the chin)This rash also occures under arms in between legs inbetween folds of buttocks and causes severe itching in all those areas. It is very hard to find any information on this subject that fits all of the symptoms however all of this together makes sense if you have the connection to this link from celiac because it gives a name to the symptoms. If you look up celiac it mentions nothing of a rash. Having the link between dermatitis herpetiformis and celiac also explains how one... if they have the rash may go about treating it by avoiding wheat and gluten if doctor prescribed medications fail to fix the problem.  — Preceding unsigned comment added by 99.100.188.58 (talk) 21:50, 19 December 2011 (UTC)
thread_title:  Please leave linked to Celiac 

message: Hello everyone, I am a fourth year medical student at UCSF who is enrolled in an elective designed to review and update selected Wikipedia articles and I have decided to tackle this article. While I think this article is quite well written, I notice there haven't been many significant changes in the past few years. There are a few things that I would like to review and update/clarify listed below that I think may strengthen this article even more. Please let me know what you all think of this plan and if you have any comments / suggestions for improvement. 
The Lead:
* I think it would be helpful to state in the first paragraph that the lesions are very itchy. 
* The current paragraph states that men and women are affected equally, while uptodate and celiac.org state that there is a slight M>F predominance in DH. 
* I would like to change the first image on this article to better reflect the typical distribution of this rash. 
Signs and symptoms:
* I would like to change this sentence somewhat to better reflect that individuals who first present with DH and have concomitant Celiac disease typically do not display the characteristic signs and symptoms of celiac's disease: "Sometimes, these symptoms may be accompanied by symptoms of coeliac disease, commonly including abdominal pain, bloating or loose stool, and fatigue."
Pathophysiology:
* I will review this content for accuracy and see if there are any new updates in the field regarding the specific mechanisms of disease.
Diagnosis:
* I would also like to include here that the concomitant diagnosis of celiac disease can be made after biopsy-proven DH and supporting serologic studies - no need for a small bowel biopsy is indicated (See section "Dermatitis Herpetiformis" - https://www.uptodate.com/contents/diagnosis-of-celiac-disease-in-adults?topicRef=15307&source=see_link#H3808958813).
Treatment:
* Currently, alternative treatments to dapsone are simply listed - I would like to expand on the available treatment options and also include options with fewer adverse side effects that are over-the-counter, such as niacin. 
* I would also like to discuss the role that topical steroids can have in ameliorating the itch associated with the rash.
Prognosis:
* I will review this section for accuracy and see if there are any new updates in the literature. 
* I will also review the consensus on if the incidence of "intestinal lymphomas" are increased in patients with DH / Celiac's disease, as this has been debated.
Timeline:
March 4: Start of elective
March 8: Proposed work-plan and timeline of changes. 
March 11: Update the 'lead' and 'signs and symptoms' sections to include the proposed changes. Will also review the 'pathophysiology' section for accuracy. 
March 15: Match day - take the next couple days off
March 20: Update the 'diagnosis' and 'treatment' sections with the proposed changes.
March 23: Review 'prognosis' section
March 25: Peer-review work
March 26-27: Final edits / updates.
March 28: End of course  — Preceding unsigned comment added by Davojann (talk • contribs) 03:14, 9 March 2019 (UTC)
thread_title:  UCSF WikiMedicine Project - Spring 2019 

message: You did a great job adjusting the article for accuracy and reorganizing the various sections for simplicity and flow. You also added great information about ongoing studies about treatment/prevention with a new vaccine and various treatment options. 
You have made great progress to reach your goals based on the timeline on your talk page. Some things to think about moving forward include:
- For treatment, think about organizing the section based on what is the recommended first line, second line, etc (and make it clear that's what you are doing). It makes for a more fluid read and helps patients clearly understand the typical recommended order of treatments.
- Expand the differential diagnosis section in 'Diagnosis'. 
- Include a history section if there is any relevant information available. 
Great work!!  — Preceding unsigned comment added by Lms 62270 (talk • contribs) 00:15, 25 March 2019 (UTC)
thread_title:  Peer Review for Wikipedia course Spring 2019