Talk:Lactate dehydrogenase

message: I am afraid that the arrow at the blue H+ on the 3rd figure has to run into the opposite direction. Pyruvate has to absorb two hydrogen atoms to become lactate. (Géza Meszéna)   — Preceding unsigned comment added by 78.139.22.49 (talk) 17:39, 17 July 2023 (UTC)
replies: text: This was written by me, here is my signature. Gezameszena (talk) 13:13, 22 August 2023 (UTC)
thread_title: Suspected Figure mistake

message: Lactate dehydrogenase is an enzyme. It is not a base. Lactate, or lactic acid, is what is found in fermented milk. There is no connection between the lactate found in skeletal muscle and that found in fermented milk.
:I got rid of that. Please note that the image is temporarily incorrect (no covalent double bond between C2 and its ketone group in pyruvate), but the wiki will figure out that I uploaded something better.  JFW | T@lk 11:47, 19 Apr 2004 (UTC)
thread_title: Untitled

message: I'm wondering if anyone (doctors) know of a reason for a massively raised LD. A patient with gallbladder cancer has an LDH of over 10000. I've never seen an LDH of that magnitude before and can't find any literature on it in those levels. Is it likely to simply be a tumour marker for this sort of cancer or is it something? --203.26.122.12 (talk) 03:31, 12 August 2008 (UTC)
thread_title: Massive LD

message: Will this enzyme be increased in mitochondrial disorders that are marked by the blood lactate increase? It is useful as a test tool in such occations? --CopperKettle 10:14, 26 January 2010 (UTC)
thread_title: Mitochondrial disorders

message: I think red blood cells can't be assigned uniquely with the LDH1, see http://www.clinchem.org/content/30/8/1353.html  — Preceding unsigned comment added by Martombo (talk • contribs) 11:32, 25 April 2012 (UTC)
thread_title:  isoforms in red blood cells 

message: Could someone change the formula
as the picture shows pyruvic acid and lactic acid,
but the enzyme substrate is pyruvate and lactate  — Preceding unsigned comment added by 131.170.90.6 (talk) 06:24, 24 September 2012 (UTC)
thread_title:  correction 

message: Someone needs to add more details to this section as it does not link nor gives any correlation of NAD+ to hypoglycemia other than simple causality. The introduction of anion gap is also out of topic.Hbk2818 (talk) 19:18, 8 December 2012 (UTC)
thread_title: Ethanol induced hypoglycemia

message: I came here to find out exactly what LDH was. I couldn't understand the introduction, so after I figured it out, I rewrote it to make it easier to understand. 
Wikipedia is written for the average reader, not the specialist. I read NEJM and Lancet every week, and I couldn't understand it. 
Please check the introduction for accuracy. But don't forget, the introduction in particular should be written for the non-technical reader. --Nbauman (talk) 05:20, 23 November 2013 (UTC)
thread_title:  Rewrote introduction 

message: The mechanism depicted here shows an arrow with a half peak instead of a full peak which is only used when 1 electron or radical is being transferred. In this reaction, it is a lone pair, regular mechanism and the arrow is incorrect. Mbenzdabest (talk) 05:16, 23 March 2014 (UTC)
thread_title:  Reaction mechanism shows incorrect flow of electrons