Talk:Legg–Calvé–Perthes disease

message: :In the US, 1 in 1200 children younger than 15 years will have this disease while in the UK 1 in 18,000 suffer from it.
     children 4 to 10 are more likely to be diagnosed
This seems a remarkable divergence: why is it fifteen times more common in the US than the UK? Loganberry (Talk) 03:59, 22 June 2006 (UTC)
replies: text: If you have reference, it always helps if you can actually cite it.  We'll need the citation if we end up using it in the article. Thanks, Bovlb (talk) 17:19, 6 February 2008 (UTC)
thread_title:  Incidence? 

message: Recently, new research has been looking at the use of bisphosphonates, such as Fosamax and Actonel, for the treatment of Legg Perthes.  Bisphosphonates are currently used for treating osteoporosis in adults.  How it works:  there are two types of bone cells, osteoblasts and osteoclasts.  Osteoblasts are bone-building cells.  Osteoclasts are bone cells that absorb and remove bone tissue.  Through the perthes process osteoclasts are at work during fragmentation and bone is lost.  Bisphosphonates stop the osteoclastic process, thereby lessening the fragmentation process and the damage caused by it.  Here's an article that talks about research into the use of bisphosphonates for perthes:  http://www.ejbjs.org/cgi/content/abstract/89/8/1727.  I have the opportunity to talk with many pediatric orthopedics and there is encouragement from this research.
Reidweaver (talk) 12:34, 12 April 2008 (UTC)
thread_title:  Bisphosphonates, A Promising Treatment 

message: In Portugal, there is a pediatric orthopedist who has been studying the growing hip to determine what factors may cause perthes.  He found what are called ischemic episodes which can often be evidenced by pain and upon investigation, show sporatic blood flow.  These episodes are precursors to Legg Calvé Perthes.  Dr. Lopes found that by inserting a very fine drill into the area, blood flow is stimulated and the episode ends.  In his research, Dr. Lopes found that of the children with ischemic episodes who were drilled, none went on to develop perthes.  Of the group who were not drilled, 50% developed the disease.  Transphyseal neck drilling is now being done in the United States as a result of this research.  http://www.geocities.com/craveiro01/pagedlcp/index.html
Reidweaver (talk) 12:54, 12 April 2008 (UTC)
thread_title:  Transphyseal Neck Drilling 

message: In the first section says there is no evidence for it being genetic, then in a later section it says it is.  —Preceding unsigned comment added by 136.8.152.13 (talk) 07:57, 27 October 2009 (UTC)
replies: text: @136.8.152.13 I had it as a child and my mother's uncle had it. We had no environmental conditions in common. 107.123.21.34 (talk) 23:07, 17 February 2023 (UTC)
thread_title:  Genetics 

message: I am a 49 year old woman who passed this disease directly to my son. What happened I don't know I was not supposed to pass this on. I did ask my specialist if I could pass this on he said no, much to my dismay I gave this to my son. My son is now 27 starting his own family, and all I can do is pray it goes no further.  —Preceding unsigned comment added by Dee dee spears (talk • contribs) 14:01, 31 October 2010 (UTC)
thread_title:  inherited 

message: Hello fellow Wikipedians,
I have just modified one external link on Legg–Calvé–Perthes disease. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
*Added archive https://web.archive.org/web/20100926081905/http://nonf.org/perthesbrochure/perthes-brochure.htm to http://www.nonf.org/perthesbrochure/perthes-brochure.htm
When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.
Cheers.—InternetArchiveBot (Report bug) 04:41, 20 December 2017 (UTC)
thread_title:  External links modified 

message: --CherieMcNaul (talk) 23:38, 27 December 2019 (UTC)
thread_title:  Leggs-Anderson-Perthes Disease in 1966 and my experience.