Talk:Progestogen-only pill

message: I'm a bit confused.  Are progesterone-only pills the same as progestin-only pills ("mini pills"), or are the two merely related?  There's currently no article or redirect for mini pill, which is a fairly common term.  --LostLeviathan 07:39, 8 August 2005 (UTC)
thread_title:  Mini pill? 

message: Let's all work on reaching a consensus for a new infobox to be placed on each individual birth control method's article.  I've created one to start with on the Wikipedia Proposed Infoboxes page, so go check it out and get involved in the process. MamaGeek (Talk/Contrib) 12:25, 14 June 2006 (UTC)
thread_title:  Proposed Infobox for individual birth control method articles 

message: "1970s  – Hormone levels decrease, the first progestin-only pill is introduced
Studies confirm that far less hormone than contained in early pill formulations is needed to prevent conception. Ortho Pharmaceutical Corporation introduces pills with decreasing estrogen and progestin levels. The company introduces the first progestin-only pill, which contains 350 mcg of norethindrone with no estrogen component, in 1973."  From "History of the Pill."  They must have studied it--and therefore "used" it--prior to 1973, which is, I assume, the date of its introduction to the general public, following approval (presumably by the FDA, in the US).  I do not know if another brand was developed elsewhere and used first.Cindery 16:10, 28 July 2006 (UTC)
thread_title: First Use?

message: here is an example of a single study, post 1996. it does not tell us if the ocs were cocp or pop or both. (i think that's relevant, which is why i'm reluctant to cite all kinds of single studies.) but per the oxford study observation, we could say dose/type of hormone doesn't matter, and it is relevant. the study notes that women who used ocs under the age of 18 had a doubled risk of breast cancer. many studies find a link between women under 35 (it is speculated that this may be because their breasts undergo more epithelial changes) which is why it was of note in the oxford study.
Cindery 01:47, 17 August 2006 (UTC)
replies: text:  Although a small risk of additional breast cancers is suspected with the higher doses of progesterones in HRTs, it is thought for the lower-dose synthetic progesterones of POPs that "overall, there is no evidence of an increased risk for breast cancer". 
Please meet each others concerns half-way and help agree on a suitable encyclopaedic consensus (remember wikipedia is not a soapbox to carry out the debate itself, but merely reports on existance of  real-world debates) David Ruben  Talk  01:41, 17 August 2006 (UTC)
thread_title: post 1996 study

message: this is a link to just one of hundreds of recent biochem/oncology studies re exogenous hormones and breast cancer.
many of them note that PRs (progesterone receptors) and ERs (estrogen receptors) have a very complicated interplay. this study describes how synthetic progestins in oc function estrogenically--through ER not PR receptors/are opposed by an anti-estrogen, not an anti-progestin. the point being i suppose that COCP/POP may not be strictly separate categories, as progestins can be estrogenic as well as progestogenic.
Cindery 03:57, 17 August 2006 (UTC)
replies: text: Norethindrone and related compounds are metabolized to ethinylestradiol in vivo by the aromatase enzyme.  Thus these pills are not truly "progestin-only" since they do have some estrogenic activity, albeit less than combined oral contraceptives. -- Kiral 09:04, 17 August 2006 (UTC)
thread_title: when progestins are "estrogenic"

message: My wife has been on a combined high-dose formulation here in Australia for many, many years. After struggling with the regular pills that have a break in dosage to allow for periods, still getting incredible pain during her periods (enough to make her nearly cry at the thought of it), she did as her doctor suggested and skipped the placebos and finally put an end to her periods altogether. I am worried about the Estrogen (Ethylestradiol) effect on her after so much negative press about it. Is there a Progesterone-only birth control that she can take to escape periods? (do not lecture on the medical ethics and dangers of doing so - she will never hear otherwise, period. Thank you.)
:Wikipedia, and for that matter any forum or website, is not the place to go assessing risks or deciding bewteen alternatives that are specifically appropriate for your wife - resee your doctor to discuss issues such as risks and alternatives (but bear in mind I read the above as indicating that the continuous combined pills are working and giving your wife a life now, presuming too that occasional breaks still taken to help prevent endometrial hyperplasia (over development)). David Ruben  Talk  09:37, 25 November 2006 (UTC)
thread_title: Efficacy Supressing Periods and With Period Pain

message: I would like to treat this parameter the same on all the hormonal contraception articles.  Please read my opinion and discuss this issue at Talk:Combined oral contraceptive pill#Weight parameter in infobox. LyrlTalk     C   21:30, 20 August 2007 (UTC)
thread_title:  Weight gain parameter in infobox 

message: I've removed the statement that the POP causes less weight gain than the COCP as the COCP doesn't cause weight gain (reference to Cochrane review in the COCP article) so I think the previous wording was misleading
Zchahe7 (talk) 14:45, 24 February 2014 (UTC)
thread_title:  Weight gain 

message: Based on CDC (United States) recommendations from (Classifications for Progestin-Only Contraceptives | CDC) - here are various situations where the risk of Progestogen-only pill may be contraindicated (Category 3+).
General
- Pregnant Patients
- Those with malabsorptive bariatric surgery (may not have effective medication based on malabsorption)
Cardiovascular Disease
(3) Current or History of Ischemic Heart Disease 
Rheumatic Disease
(3) Positive Antiphospholipid antibodies
Breast Disease (such as cancer)
(4) Current
(3) Past but no evidence of disease for 5 years
Liver Disease
(3) Severe Cirrhosis
(3) Liver Tumors Hepatocellular Adenoma
(3) Liver Tumors Malignant Hepatoma Kmsmola (talk) 12:42, 27 October 2023 (UTC)
replies: text: Related and Different Contraindications exist for Progestogen Implantable Devices as well as DMPA, but I was trying to focus on Progestogen-only pills as the title of the article recommends, unless others feel all related information should be provided. Kmsmola (talk) 12:45, 27 October 2023 (UTC)
thread_title:  Contraindications (Risk > Benefit) 

message: First Generation
- Norethindrone Acetate (0.35mg tablets; commercial name Camila/Errin)
- Ethynodiol diacetate
- Lynestrenol
- Norethynodrel
Second Generation
- di-Norgestrel (28 tabs of 0.075 mg; Commercial name Opill)
- Levonorgestrel
Third Generation
- Desogestrel (75 mcg POP forumulation)
- Gestodene
- Norgestimate
Unclassified
- Drospirenone (package containing 24 tabs with 4mg of drospirenone; commercial name Slynd)
- Cyproterone Acetate Kmsmola (talk) 12:56, 27 October 2023 (UTC)
thread_title:  Available Formulations