lflage/wiki-talks huggingface dataset:
Talk:Byssus

message: I came across an article some other readers of wikipedia can definitely expand upon. This has do to with the face covering or 'sweat cloth' as I see in some references to it of the linen cloth that was found in the tomb Christ was laid to rest. In a debate about what happened to Veronica's veil one researcher made reference to a small capuchin monastery in Italy that has this face covering made of Byssus linen that has the imprint of Christs' face that matches the the Turin Shroud. The interesting aspect of this byssus linen cloth with the image is that it is translucent and has no visible markings one associates with paint of any kind. When held up to light it has the golden tint byssus fibers lend to linen. I will dig deeper with the resources I have at hand to update this entry. I surmise that Veronica's veil was made of the same material so that the imprint would fixate into the material and be crystal clear in appearance without intervention of the filtering of a human mind or hand upon it. My take on this is that Christ would not allow the profane or infidel to abuse a relic so sacred, or that it would be manipulated for mass scale marketing. By this I mean, for instance,  Mel Gibson sold copies of crucifixion nails when his Passion film was shown. I foresee 1,000 years down the line when none of us are around to protest, that these promo nails will be huckstered as the real thingJaako 23:45, 16 February 2007 (UTC)
thread_title: A note
Talk:Laccase

message: According to the Chemical Abstracts, laccase is the subject of >24,000 reports, of which 23,339 have appeared since the year 2000 (about 3 papers/patents etc per day). 811 reviews have appeared since 2000.  None of the top 10 reviews (in terms of citations) are mentioned in this article.
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Please be mindful of WP:SECONDARY when such sources exist.--Smokefoot (talk) 23:18, 4 March 2022 (UTC)
thread_title: SciFinder report March, 2022

message: Added in some biological application related to laccase. Included some  proposed mechanisms involved in laccase related reactions.  Kthk0708 (talk) 03:39, 6 December 2022 (UTC)
replies: text: Is there any additional edits that I can make aside from what was already added. Please let me know. Kthk0708 (talk) 03:40, 6 December 2022 (UTC)
thread_title:  Edits made Dec 2nd , 2022
Talk:Lingual lipase

message: What exactly is meant by: "In the uterus, the fetus is dependent on a high-carbohydrate diet"  Fetuses do not eat. Fetuses are nourished via substrate exchange across the placenta.  —Preceding unsigned comment added by 169.230.237.173 (talk) 01:12, 21 April 2011 (UTC)
thread_title: Untitled
Talk:Oxidase

message: The sentence "Some oxidation reactions, such as those involving monoamine oxidase or xanthine oxidase, typically do not involve free molecular oxygen." is not clear. I don't know what the author intended to say, but I read it as monoamine oxidase and xanthine oxidase do not require Oxygen (O2) to function, which clearly is not true. LolloC92 (talk) 14:48, 15 February 2024 (UTC)
thread_title:  Sentence not clear
Talk:Lysyl oxidase

message: http://www.newscientist.com/article/dn9064--lox-holds-a-key-to-curbing-cancers-spread.html
http://www.nature.com/nature/journal/v440/n7088/full/nature04695.html  —Preceding unsigned comment added by 212.120.101.141 (talk) 14:25, 10 March 2009 (UTC)
thread_title: Untitled
Talk:NADPH oxidase

message: :Merged from Talk:NAD(P)H_oxidase
NADPH oxidase looks to be the same thing. So they should be merged.  Also the interwikilinks seem to be split between the articles. I picked this one as the target as it had a better enzyme box, but pick the best name.  Graeme Bartlett (talk) 08:12, 24 January 2018 (UTC)
replies: text: Support - I agree that they're referring to the same thing and should be merged. The acronyms NADPH and NAD(P)H are used about equally in the literature, but our other pages tend to favour NADPH, so I'd suggest NADPH_oxidase as the merged location. T.Shafee(Evo&Evo)talk 03:46, 5 July 2018 (UTC)
thread_title: Merge
Talk:New Fairfield Historical District

message: This article was nominated for speedy deletion on the ground that it was a short article and did not provide sufficient context for the information provided. After reviewing the nomination, I have decided not to speedy-delete because the article was just created today and the author, who is a good-faith contributor, may intend to add more information. If this does not occur after a few days, the article may be retagged. Newyorkbrad 23:51, 16 February 2007 (UTC)
replies: text: Much of the content you propose is sourced to either primary sources or user-created genealogies, and does not seem appropriate for an article on any notable topic AFAICS. What would you propose splitting it to? Nikkimaria (talk) 23:48, 15 March 2023 (UTC)
replies: text: Nikkimaria:  On reviewing the deleted material, I think you are right.  It seems to be more suitable for some genealogical record than this article.  And the information is accessible in the article's history if someone wants to preserve it elsewhere.  So it looks like we agree. Postazoic (talk) 07:54, 16 March 2023 (UTC)
Talk:Respiratory burst

message: I’m Chloe Foo, a final year Biochemist at Imperial College London. I will be editing this Wikipedia article as part of my Science Communications module. I intend to add detail to the concepts already discussed in the current article, and broaden the included information, particularly regarding the different pathways of free radical generation in the Respiratory Burst. I will also include my own figures to summarise and better visualise the material. Chloefooey (talk) 01:18, 12 March 2020 (UTC)
thread_title: Science Communications Assignment

message: I am currently restructuring and rephrasing sentences, as well as adding more detail. I am likely to remove the detail about plants as that information is more relevant to the Reactive Oxygen Species Wikipedia article and is weakly linked to the Respiratory Burst. Chloefooey (talk) 01:18, 12 March 2020 (UTC)
thread_title: Edits

message: : I'm sorry to have to drop by and say this, but it is not really acceptable to add content and then ask around for people to find references to support it. This suggests you've simply added content based upon what you've learned in lectures. As a third year student, you should know better than that. 'Cite sources to support content, or don't add the content' is a good approach to take - especially on technical subjects.  Wikipedia also asks editors to explain each edit with a clear WP:EDITSUMMARY, and your omission in every edit you've made is not helpful either - especially where you've removed an entire section of cited content on this process occurring in plants. As we're none of us mind-readers, please could you explain your reasoning for that deletion here, please? (Please remember to sign your posts on talk pages by typing four keyboard tildes like this: ~~~~. Is it an error that you state your assignment ended in March 2019, not 2020? Without the inclusion of a timestamp, which four tildes inserts for you, we all end up a bit confused as to when you're editing and commenting.)   Many thanks, Nick Moyes (talk) 00:27, 12 March 2020 (UTC)
replies: text: I mentioned that I am in the process of adding references, and would appreciate help if any - however your point is noted and I will source the information added myself. I briefly mentioned in the section above that I removed the plant content as I did not believe that it implicated the respiratory burst, but rather, free radicals. I have just re-included said information for later review on relevance. As this is my first time editing a Wikipedia article, I was not aware that I had to explain my edits in the WP:EDITSUMMARY and had simply explained myself in the Talk page. I will include explanations of further edits in the WP:EDITSUMMARY from here on. Your feedback is appreciated. Thanks, Chloefooey (talk) 01:40, 12 March 2020 (UTC)
thread_title: Comments
Talk:Methyltransferase

message: Not mentioned or defined in article. 109.157.79.50 (talk) 07:31, 9 January 2015 (UTC)
thread_title:  Why does "transmethylase" redirect here? 

message: Could someone include reference to this information from https://www.bbc.com/news/health-49682583 Common cold stopped by experimental approach, viruses were unable to replicate inside cells which had the instructions for a protein (called methyltransferase SETD3) switched off?  — Preceding unsigned comment added by 114.30.103.1 (talk) 22:58, 16 September 2019 (UTC)
thread_title:  Role of Methyltransferase in the Common cold
Talk:Ross Hunter

message: The article currently states (citations omitted):
Hunter was born Martin Terry Fuss in Cleveland, Ohio on May 6, 1926. He was of Austrian-Jewish and German Jewish descent. Hunter attended Glenville High School where he later taught English and drama (he also taught these subjects at Rawlings High School). During World War II, he worked in United States Army Intelligence. After his time in the Army, he returned to his job as a drama teacher. He eventually moved to Los Angeles after his students sent his photo to Paramount Pictures. Paramount Pictures passed on signing him to a contract and he subsequently signed with Columbia Pictures. It was at Columbia that a casting agent changed his name from "Martin Fuss" to "Ross Hunter".
During the 1930s, Hunter acted in a number of B-movie musicals.
If Hunter was born on May 6, 1926, then he would only have been 13 years old when the 1930s ended. Yet the implication from the prior paragraph is that he didn't become a movie actor until after World War II and having been a high school teacher. I don't claim to know what the exact chronology of his life was, but it seems unlikely that if he was born in 1926, he would have had time to become a high school drama teacher before serving in Army Intelligence during World War II, given that the war ended when he was (purportedly) 19 years old. --Metropolitan90 (talk) 06:37, 7 March 2016 (UTC)
replies: text: You're right. It seems to me unlikely that he was a high school drama teacher as a minor! --Clibenfoart (talk) 12:49, 21 October 2019 (UTC)

text: - This is over a year and a half ago, but some sources indicate that he was born as early as 1916 (per his obituary from the Los Angeles Times): "His age was variously reported between 69 and 79 ... Film guides variously report that Martin Fuss was born between 1916 and 1926 in Cleveland, Ohio." But if he was born on May 6, then the 1920 birth year would be supported by his New York Times obituary, stating that he died aged 75 in March. Although Hunter's page doesn't indicate when he began his army service, since he completed his service by 1943 or 1944 (1944 was when he made his first movie, though the movie may have been filmed in 1943, and then released in 1944, IDK), then the 1916 would seem more likely then the 1920 birth year. Clear Looking Glass (talk) 16:42, 12 April 2021 (UTC)
replies: text: Quite a birth mystery as it is with Joan Crawford. I think we can't be sure about the exact date, but any date later than 1920 seems highly unikely (and thankfully it has been changed in the meantime). --Clibenfoart (talk) 17:30, 12 April 2021 (UTC)
replies: text: I’ve added a note on his page explaining the situation, but yes, I think we can safely rule out anything after 1920 given what we know of his life. Clear Looking Glass (talk) 17:53, 12 April 2021 (UTC)

text: I believe Martin Fuss was most likely born in 1916.  He was my mother's English teacher and she was born in 1926. Cory0908 (talk) 14:40, 13 July 2023 (UTC)
thread_title:  Age discrepancy
Talk:Mucunain

message: Apparently the hairs can cause blindness if they get in the eyes (this article just says they cause pain). http://consejo.bz/belize/poisonplants.html  — Preceding unsigned comment added by Erlendd (talk • contribs) 10:42, 17 October 2011 (UTC)
thread_title:  Blindness if hairs get in eyes?
Talk:N-Acetylglutamate synthase

message: 1- in bacteria NAG is produced from OAT enzyme, at earlier place you said that: "NAG can be used in the production of ornithine and arginine" so I conclude that OAT help producing both ornithine and arginine, but OAT have defined as an enzyme in (cyclic ornithine production pathway) only and didn't mention it as also produce arginine.
2- as said above: in bacteria OAT synthesize NAG so NAGS act as supplementary, (then you said)  In some plants and bacteria, however, NAGS catalyzes the first step in a ‘linear’ arginine production pathway.
we conclude that the latter arginine synthesis do not happens through NAG (otherwise it will also act as NAG supplement and not contrast with it).
"just to ascertain this"
3- (the role of arginine as an inhibitor of NAG in ornithine and arginine synthesis)
didn't say if it is for vertebrates or bacteria:
if for vertebrates: a contradiction happens because we know that arginine act as effector for NAGS in vertebrates:
(L-arginine acts as an inhibitor in plant and bacterial NAGS "but an effector in vertebrates.")
unlikely that it stimulate NAGS but inhibit overall NAG (at least such paradox have never been mentioned)
and if it was for bacteria: then the mechanism would be missing: because although in bacteria arginine inhibit NAGS, but we knew
that it is not NAGS that carry out NAG synthesis in bacteria, but it is OAT (NAGS act supplementary or in arginine linear pathway)
so we should find something else: like if arginine inhibit OAT also, or some direct inactivation of NAG....
apart from these points (that mostly due to the many articles that antagonize each other), the article is wonderful and I thank whoever edited it.
Yasir muhammed ali (talk) 05:28, 12 April 2016 (UTC)
thread_title:  several confusing points:
Talk:Ferredoxin

message: For the structural artists: Cys-S would be some sort of perthiolate or something else, such as is invoked for rhodanese.  Cys = the cysteinyl residue (including the S), not the cysteinyl residue less the sulfur.  Or maybe I am misunderstanding some sort of convention, which is possible. --Smokefoot (talk) 19:49, 23 December 2007 (UTC)
thread_title: Cys-S is not cysteinyl

message: As far as I know, in Ferredoxin Clostridien pasteurianum has two Fe4/S4 Cluster and not Fe2/S2 - Cluster. The Fe4/S4-Cluster is also called "Clostridien-Type"  —Preceding unsigned comment added by 78.53.195.244 (talk) 14:42, 7 November 2008 (UTC)
thread_title: Fe4/S4 Cluster
Talk:Orotidine 5'-phosphate decarboxylase

message: What's that 5' notation ? —Jerome Potts (talk) 13:01, 5 September 2020 (UTC)
replies: text: Well i finally found where it explains that, at Directionality (molecular biology). Note the nothing in enzyme, nor protein. So, how about sticking some of that in here ? Also, apparently the correct notation uses the prime character, ′, not the apost '. —Jerome Potts (talk) 13:24, 5 September 2020 (UTC)
thread_title:  5'
Talk:List of EC numbers (EC 1)

message: In the text, the entries for 1.4.1.3 and 1.4.1.4 are identical, likely an error.  In the wikipedia article on Glutamate dehydrogenase, these are listed as:
* EC 1.4.1.2: L-glutamate + H2O + NAD+ \rightleftharpoons 2-oxoglutarate + NH3 + NADH + H+
* EC 1.4.1.3: L-glutamate + H2O + NAD(P)+ \rightleftharpoons 2-oxoglutarate + NH3 + NAD(P)H + H+
* EC 1.4.1.4: L-glutamate + H2O + NADP+ \rightleftharpoons 2-oxoglutarate + NH3 + NADPH + H+
The entries should be corrected using the standards body as source  — Preceding unsigned comment added by 70.72.144.66 (talk) 23:40, 22 November 2013 (UTC)
thread_title:  EC 1.4.1 entries
Talk:Myeloperoxidase

message: The search for biomarkers of joint disease in the horse is the subject of several current research works, so the entrance regarding the assessment of MPO in equine synovia is an important contribution for all scientists working in this field. This is why I do not agree with Jfdwolff when he sais that my contribution is of questionable importance. Anastasios Moschos  —Preceding unsigned comment added by Anastasios Moschos (talk • contribs) 00:46, 2 November 2008 (UTC)
replies: text: I think there are two issues. Firstly, while assuming good faith I notice you are the main author of your primary source, which indicates a potential WP:COI. Secondly, your contribution doesn't indicate a current practical application of the research you are alluding to. JFW | T@lk 13:24, 2 November 2008 (UTC)
thread_title: Untitled
Talk:Lyase

message: It may be obvious to a biochemist that converting ATP to cyclic ADP is a lyase reaction, but it's not obvious to the ordinary reader.  And someone who knows the structure of ATP and ADP probably already knows what 'lyase' means, so they don't need this example.  A better example for the ordinary reader would show a structure, not just the names of the input and output, maybe like this: http://www.differencebetween.net/science/differences-between-glucose-and-sucrose/  (I don't know whether that counts as a lyase reaction, but the point is that the actual structure is shown.) Mcswell (talk) 02:59, 17 July 2021 (UTC)
thread_title:  Better example needed
Talk:Denpasar

message: Hi there! I am planning on including a new section on the Denpasar article that covers the architecture of the city. The reading that I intend on using to support my plans to improve the article is, 'Reading urban Bali: untold history, unwanted urbanism' written by  Amanda Achmadi, in RIMA: Review of Indonesian and Malaysian Affairs, Vol. 44, No. 2, 2010: 149-178. --Naasri2 (talk) 21:19, 13 November 2016 (UTC)
thread_title:  Denpasar – Architecture 

message: Okay, on the top right of the page, why are Catholics listed separately from Christians?  As Catholics are Christian, it confuses me.  If someone meant other Christians, such as Protestant, they should list that.  Thanks! Adam (talk) 18:20, 12 June 2017 (UTC)
thread_title: Confused about religious listings
Talk:Phosphofructokinase 2

message: I think that this enzyme’s bifunctionality should be more greatly emphasized and explained. I have a couple of specific edits I would like to make in hopes of improving this page. These include:
-adding a 3D ribbon/surface model image that more specifically displays secondary protein structure and active sites to supplement “Structure” section
-images/space filler models that display structural difference between the PFK-2/FBPase2 and each enzyme state appears depending on which domain is phosphorylated (perhaps using zoomed-in, stick model to show when Ser-32 is phosphorylated)
-Clarify the “Reaction mechanism” section by creating an accompanying image - I think that readers could benefit by having a picture of the reaction for reference when reading the different steps
-Add cycle diagram to show how enzyme regulates glycolysis and gluconeogenesis so that readers understand switch from fructose-6-phosphate to fructose-2,6-biphosphate; hopefully this would visually supplement the “Regulation” section 
-Potentially adding how a clearer difference between muscle/liver action, and within liver, fed/fasting state? Or would that be too specific to include in this article?
Thoughts? Thanks!
Kedrosolan (talk) 20:14, 15 February 2018 (UTC)
thread_title: several suggestions/media improvement

message: It seems the name of this gene is outdated, I propose a merge to: https://en.wikipedia.org/wiki/PFKFB1  — Preceding unsigned comment added by Ethylfox (talk • contribs) 15:40, 13 July 2015 (UTC)
thread_title: merge proposal

message: This enzyme is being recognized as a key regulator of carbohydrate metabolism. It is also being increasingly referred to as the "bifunctional enzyme". The latter, though it seems disturbingly nonspecific, is certainly easier than the messy combination of both enzyme names. Is anyone else in favor of renaming the principal article bifunctional enzyme, and changing this phosphofructokinase 2 to a redirect-- i.e., the opposite of current situation? alteripse (talk) 11:45, 11 April 2009 (UTC)
thread_title: nomenclature and importance
Talk:Secretin

message: The amino acid sequence of secretin is given here starting at the C terminus and ending at the N terminus, against normal convention to write the sequence from N->C.  Is entire sequence backwards? Or did original author/ editor simply switch the COOH/NH2 end labels?  —Preceding unsigned comment added by 130.49.146.57 (talk) 03:10, 2 November 2009 (UTC)
replies: text: Good catch.  The sequence is written in the correct N- to the C-terminus direction (see UniProt P09683, residues 28–54), but the CO2H/NH2 end labels were reversed from what they should be.  This error has now been corrected.  The confusion may have been caused by the fact that the C-terminus is amidated (CO2H → CONH2). Boghog (talk) 06:35, 17 September 2010 (UTC)
replies: text:  I believe it is typical to represent c-terminal amidation by "-NH2" rather than "-CONH2" as this would imply that the carbonyl group is not part of the residue's definition. I have changed this. Please advise if this is incorrect. For example, see "davalintide" in INN list 101. http://www.who.int/medicines/publications/druginformation/innlists/PLFinal101.pdfPeryeat (talk) 21:19, 14 May 2013 (UTC)
thread_title:  Amino Acid sequence listed C -> N termini? 

message: Pretty sure secretin does not DIRECTLY inhibit gastrin secretion (otherwise, how do you explain ZES which is essentially an XS of G cells?). Instead, its inhibitory function is mediated via somatostatin. Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC370446/ Normally, somatostatin inhibition exceeds the enhancement of gastrin secretion by secretin, but in ZES, this goes out of whack because of the XS of G cells relative to D cells, hence an upward elevation in gastrin with secretin stimulation in ZES. I don't know how to word the above in a concise format.
Source: my GI professor, but I'm sure there are other sources out there e.g. http://www.ncbi.nlm.nih.gov/pubmed/2565843
Jimhsu77479 (talk) 20:02, 17 September 2011 (UTC)
thread_title:  Secretin and gastrin inhibition 

message: The article says that secretin has been proposed as a possible treatment for autism based on a hypothetical gut-brain connection, but there's more to it than that. Secretin has been demonstrated to increase activity in the amygdala, a part of the brain dysfunction of which is linked to autism. http://www.autism.com/ARI/newsletter/182/page2.pdf
http://www.autism.com/ARI/newsletter/182/page2.pdf
--CanuckBC (talk) 08:40, 12 February 2012 (UTC)
thread_title:  Secretin to Treat Autism 

message: I want to know if it might be a good idea to include a sentence in the introductory paragraph describing that secretin is the "first hormone" to be discovered, as it would be something significant about secretin. Somerandomuser (talk) 16:50, 7 June 2017 (UTC)
thread_title:  Mentioning First Hormone
Talk:Parkin (protein)

message: I'll try to get to this page over the weekend.  However if someone else can add in the box with the OMIM, entrez numbers, etc that would be very helpful.
Currently the page is rather a mess....
Gacggt 16:02, 27 March 2007 (UTC)
thread_title: Untitled

message: PARK2 is not the name of the gene. Parkin is the name of both the gene and the protein it produces. PARK2 designates the type of Parkinson's disease caused by a genetic defect in the parkin gene. I don't know why they don't have two names but that's scientists for you! 86.19.99.37 (talk) 15:35, 21 March 2012 (UTC)
thread_title:  PARK2
Talk:Poly (ADP-ribose) polymerase

message: Many times this article talks about 'PARP' - Is it referring to PARP1 or PARP-activity ? - Rod57 (talk) 10:57, 12 July 2016 (UTC)
thread_title:  Clarify what PARP is - activity or PARP1 

message: Need more comparision of  the family members, eg. sequences, shapes, PARP activity, function, location, epigenetic-control ... - Rod57 (talk) 11:29, 12 July 2016 (UTC)
thread_title:  Need more comparision of  the family members 

message: Beyond DNA repair, the immunological role of PARP-1 and its siblings. - Rod57 (talk) 11:33, 12 July 2016 (UTC)
thread_title:  Possible source