Talk:Progressive supranuclear palsy

message: It should be reversed.
:What should be reversed? JFW | T@lk 14:21, 20 October 2005 (UTC)
thread_title: older talk

message: I tried to add a reference about Anne Turner, following the format of references in use elsewhere in the article, but couldn't get it to work. So have used a standard "cite web" and "reflist".  If anyone wants to tidy this ref to make it match the others, please do so! PamD (talk) 22:09, 25 January 2009 (UTC)
thread_title:  adding a new ref 

message: I came to this article because I read an obituary of someone who had died from it. The article here, however, while clearly implying that the disease is often fatal, doesn't say much about the later stages of the disease, why it is fatal, and the mortality rate. I suppose 100% might be inferred, since the article does say that sufferers usually survive seven years after initial diagnosis. However, a little more information might help.  — Preceding unsigned comment added by 96.49.86.147 (talk) 02:57, 27 May 2011 (UTC)
thread_title:  later stages 

message: This article on PSP (Progressive supranuclear palsy) says it's "a rare degenerative disease", whereas the article on ALS (Amyotrophic lateral sclerosis) says it's "one of the most common neuromuscular diseases worldwide".  But based on the numbers in each of the articles, it would seem that PSP is more common than ALS.
http://en.wikipedia.org/wiki/Progressive_supranuclear_palsy starts off by saying, "Progressive supranuclear palsy ... is a rare degenerative disease ... Approximately 6 people per 100,000 population have PSP."  In contrast, http://en.wikipedia.org/wiki/ALS#Epidemiology says of that disease, "ALS is one of the most common neuromuscular diseases worldwide ...  One or two out of 100,000 people develop ALS each year."
Of course, comparing number of people who have a disease to number of people who develop a disease each year is comparing apples and oranges.  BUT the ALS article also says, "ALS is a progressive, fatal, neurodegenerative disease with most affected patients dying of respiratory compromise and pneumonia after 2 to 3 years ..."  This makes it easy to estimate how many people are living with ALS.  At the low end, figure one out of 100,000 people develop ALS each year, and most survive for 2 years.  That's 2 people per 100,000 population.  At the high end, figure two out of 100,000 people develop ALS each year, and most survive for 3 years.  That's 6 people per 100,000 population.
So, a disease that afflicts between 2 and 6 people per 100,000 population is described as "one of the most common neuromuscular diseases worldwide", whereas a different disease that afflicts approximately 6 people per 100,000 population is described as "a rare degenerative disease".
http://en.wikipedia.org/wiki/Huntington%27s_disease seems an appropriate model for handling this.  It just provides the numbers without editorializing.  http://en.wikipedia.org/wiki/Huntington%27s_disease#Epidemiology simply says, "The worldwide prevalence of HD is 5-10 cases per 100,000 persons."  So, based on that model, I've removed the word "rare" from the PSP article.  — Preceding unsigned comment added by Mark Rosenthal (talk • contribs) 16:54, 21 October 2011 (UTC)
thread_title:  Rare? Definition is inconsistent between articles on neuromuscular diseases. 

message: doi:10.1093/brain/awq115 was in the external links, but should serve as a reference instead. JFW | T@lk 16:26, 28 January 2013 (UTC)
thread_title:  Brain review 

message: Someone who is very dear to me is having this. Several clarifications in parentheses makes the "Signs and symptoms" section fairly easy to read for someone with no specific medical knowledge. Thanks, good work. Paulus/laudaka Laudaka's talk page 20:01, 13 March 2013 (UTC)
thread_title:  Thanks for good explanation in "Signs and symptoms" section 

message: This section needs references and is not entirely without controversy. See, e.g.,  http://www.ncbi.nlm.nih.gov/pubmed/10388790 - Clinical genetics of familial progressive supranuclear palsy 
Page Notes (talk) 00:50, 13 June 2013 (UTC)
thread_title:  Genetics and causal factors 

message: added two case reports about response to Zolpidem CR. This is fascinating considering the lack of serious treatment options for PSP, but unfortunately they are both case reports and on Wikipedia we can really only discuss treatments found effective in secondary sources. For rare diseases, a single recent high-quality review in a core journal should be sufficient to serve as a source. Please refer to WP:MEDRS for more information. JFW | T@lk 20:35, 3 November 2014 (UTC)
replies: text: Thank you for the information and link. I shortened and updated the original edit on zolpidem with citations from literature reviews. I appreciate the help! JLKoike (talk) 03:04, 4 November 2014 (UTC)
thread_title:  Zolpidem CR 

message: The top graphic accompanying the article on the right panel lists the anatomical planes as Horizontal, Sagittal, and Frontal. The Wikipedia page on Anatomical Planes (https://en.wikipedia.org/wiki/Anatomical_plane) lists them predominantly as Transverse, Sagittal, and Coronal, respectively. Although "horizontal" and "frontal" are listed as "also known"s, I've never seen orientation listed as such in medical literature. I didn't think it was a pressing issue, but I also didn't know if this graphic is used elsewhere in cerebral anatomy and wanted to post the issue for discussion. Enotdetcelfer (talk) 00:28, 30 December 2016 (UTC)
thread_title:  Anatomical Planes 

message: doi:10.1016/S1474-4422(17)30157-6 JFW | T@lk 09:58, 21 June 2017 (UTC)
thread_title:  Lancet Neurol 

message: I have removed this section of the article. The general view of the Medicine WikiProject is that names only belong in sections of this sort if the people are specifically notable for having the condition, for example Michael J. Fox in Parkinson's disease. I did not see any evidence that any of the names in the list met that criterion. Looie496 (talk) 17:21, 22 March 2018 (UTC)
thread_title:  Notable cases 

message: Eventhough an apathetic state may be seen earlier in disease true dementia is seen only in the advanced stages of the disease.This is what is given in most of the literature in contrast to what is written here in signs and symptoms. Think it requires correction (Angunnu (talk) 05:55, 18 November 2019 (UTC)
thread_title:  Dementia in PSP