Talk:Obesity hypoventilation syndrome

message: Hi, the average man is not going to be able to understand this stuff! Perhaps someone should tone it down from it being a reference text for nuerologists, to something the average human being can understand?? --211.28.125.210 07:47, 23 April 2007 (UTC)
replies: text: It also gives almost no information on the management of the condition. This is a 2001 review we could use to make it a more useful resource. With obesity becoming a major public health problem, we are already seeing a lot of this. JFW | T@lk 07:27, 13 January 2008 (UTC)

text: Sorry, the Chest paper is a research paper. Instead, I thought  would be useful for an eventual update of this article. JFW | T@lk 08:14, 13 January 2008 (UTC)

text: And there's , which isn't free yet. JFW | T@lk 08:16, 13 January 2008 (UTC)
thread_title:  

message: is a very recent review. Unfortunately this is not available free, and I am therefore working from Olson et al in updating this article. JFW | T@lk 10:24, 20 January 2008 (UTC)
replies: text: Bizarrely, PubMed doesn't list Burwell as the first author of the 1956 Am J Med paper, even though every citation of it and the 1994 reproduction do so. Anyone have an explanation? JFW | T@lk 11:31, 20 January 2008 (UTC)
thread_title:  More recent 

message: Having access to Mokhlesi's 2007 review, as well as another paper from his hand () I am now expanding this article and will hopefully get it up to GA status.
My worklist for each section:
*  Signs and symptoms - update with Mokhlesi on physical features and comorbidities
*  Pathophysiology - update from Mokhlesi (may need substantial rewrite and diagram)
*  Criteria - update with list of conditions to be formally excluded (narcotics being just one)
*  Diagnosis - perhaps an image?
*  Treatment - more detail, especially using Mokhlesi's 2008 review with a useful flowchart
*  Prognosis - to be written
*  Epidemiology
*  History - when did the term OHS replace Pickwickian?
** Question on nomenclature posted on WT:MED
* Other - images would be nice
Anyone interested in helping is welcome, as usual. JFW | T@lk 09:24, 23 November 2008 (UTC)
replies: text: The Mokhlesi 2008 review is not greatly different from the 2007 review, apart from being published in different journals. I'm sticking with the 2007 review for now, as it is more elaborate. The only important part of the 2008 review is the algorhythm for acutely decompensated OHS. JFW | T@lk 15:09, 23 November 2008 (UTC)
thread_title:  Improvements 

message: In "mechanism" I'm citing , but I've only seen the abstract of that review. I've requested the fulltext on WP:WRE to see if the article needs supplementing. Likewise, I need to review Harrison's to see if there is any discrepancy there with our current content.
Images would be nice, but apart from the CPAP machine I'd need to draw some sort of diagram to make this look pretty.
Once this is done, off to GAC it is. JFW | T@lk 16:43, 23 November 2008 (UTC)
replies: text: Article reviewed. Not much more compared to the other sources. Off to GAC soon. JFW | T@lk 13:04, 25 November 2008 (UTC)
thread_title: Stuff still to do

message: I have looked through a couple more respiratory physiology & sleep textbooks, and I didn't find any mention of papilloedema. The BMJ article is a case report, and references other case reports. Given the rarity of this clinical feature in this setting, I think that it is better to remove papilloedema from the Wikipedia article. Axl ¤ [Talk] 10:41, 4 December 2008 (UTC)
replies: text: So much for Bob Ryder's classic PACES text marking it out as a classic feature of hypercapnia... I'll kill it. JFW | T@lk 12:03, 4 December 2008 (UTC)
thread_title:  Papilloedema 

message: From "Mechanism", paragraph 1: "Firstly, people with obesity need to expend much more energy (about fivefold, or fifteen percent of overall energy consumption) to breathe effectively, as adipose tissue restricts the normal movement of the chest muscles, the diaphragm moves less effectively, the chest wall is less compliant, respiratory muscles are fatigued more easily, and airflow in and out of the lung is impaired." (Emphasis mine.) This long sentence should be simplified. Also, I am unsure where these figures come from. In the ironically named "Handbook of Obesity" (it stretches the meaning of the word "Handbook", all puns intended), p. 726 "Work of breathing can be increased two- to three-fold even in obese eucapnic patients." Axl ¤ [Talk] 09:45, 5 December 2008 (UTC)
replies: text: I have rephrased the sentence in "mechanism". The figures on increased energy expenditure are actually oxygen expenditure. I took it from Mokhlesi, who cites it to . There are no figures comparing obese eucapnic people with OHS patients. I have no access to the sources you have provided. Please don't hesitate to add them to the article if you think they enhance the current content. JFW | T@lk 10:59, 5 December 2008 (UTC)
replies: text:  I saw that article in the AJRCCM and I considered including it above, but it didn't really add anything extra. The patients in the AJRCCM study had an average BMI of 53: some would classify this as "super obese", even higher than morbidly obese. It's unsurprising that this group of people have even higher VO2Resp than "regular" obesity. The third reference above has a free on-line link. Axl ¤ [Talk] 10:22, 6 December 2008 (UTC)

text: The third reference looks interesting, but as a primary research study it doesn't really add much—unless you disagree. JFW | T@lk 20:41, 6 December 2008 (UTC)
thread_title:  Energy consumption 

message: Stop press! Just found another review in Thorax this year. It's actually part of a larger series on obesity and the lung (part 1 epidemiology , part 2 sleep disordered breathing , part 3 intensive care , part 4 asthma , part 5 COPD ). I will track down the paper and integrate any useful content into the article. JFW | T@lk 11:07, 5 December 2008 (UTC)
replies: text: The Thorax paper is very good, but it makes roughly the same points and is shorter than Mokhlesi. At present I can't see any points we need to cite preferentially from this paper. JFW | T@lk 01:26, 9 December 2008 (UTC)
thread_title:  Review in ''Thorax'' 

message: Dear all, My English is not good enough to write for the English version of wikipedia and I am already active on the Dutch version of wikipedia. I wanted to point out a new article from the New England Journal of Medicine that states that the CPAP doesn't prevent cardiovascular events. "CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea" I Hope someone can address this correctly in the article and in the article of sleep apnea. Yours Doctodoc (talk) 12:19, 23 September 2016 (UTC)
thread_title:  NEJM article 

message: doi:10.1177/0885066616663179 - critically ill patients with OHS. JFW | T@lk 10:58, 21 July 2017 (UTC)
thread_title:  New review 

message: doi:10.1164/rccm.201905-1071ST JFW | T@lk 21:22, 22 August 2019 (UTC)
replies: text: Also this in Eur Resp Rev doi:10.1183/16000617.0097-2018 JFW | T@lk 21:22, 22 August 2019 (UTC)
thread_title:  ATS guideline 

message: https://www.nice.org.uk/guidance/ng202
JFW | T@lk 20:31, 4 December 2021 (UTC)
thread_title: NICE