Talk:Urea-to-creatinine ratio

message: Considering that people might check wikipedia regarding their pet's renal condition, shouldn't it be clarified that all values in this article are for humans only? Dr.queso (talk) 23:08, 14 August 2011 (UTC)
thread_title: Shouldn't we clarify what species we're talking about?

message: To me, the term 'ratio' implies the units cancel one another out to create a dimensionless number. Shouldn't the urea to creatinine ratio therefore be 100:1 rather than 1:10 (with creatinine measured in micro moles/L and urea in millimoles/L)? Whyso (talk) 11:28, 15 July 2009 (UTC)
thread_title: Urea:Creatinine ratio

message: The chart columns are very misleading. First of all, there are no indications whether the first or second column are in SI or US units. Skimming the history, This was changed a few months ago, only to be changed back to its current (erroneous) state.
BUN, to my understanding, is used more in the US. So I'll assume the first column is in US units, and the second is in SI.
If that is the case, then, the second column may be in error. Cr is measured in micro-mol/L, while Urea is measured in millimol/L. Therefore, Ur is three orders of magnitude larger than Cr. It makes no sense, then, to have Cr:Urea of 10:1 -- to have that is to imply that the person has a Cr of 10,000 micromol/L for a Urea of 1 millimol/L.
If there are no further comments to this, I will change it back again to agree to SI units.
Why should a high BUN/creat ratio have a high specificity for GI bleeding, while it should not be caused by protein digest? If it were solely a matter of prerenal renal insufficiency, all causes  with comparable volume depletion would cause a similar BUN/creat ratio. Therefore I think the digestion of protein is a major contributor to the increased BUN/creat ratio.  —Preceding unsigned comment added by 92.65.112.140 (talk) 10:05, 19 April 2011 (UTC)
thread_title:  Units changed yet again 

message: When BUN reabsorption is increased, then this results in a lower amount of BUN in the urine and a lower BUN:Cr ratio in the urine.  Because reabsorbed BUN goes back into the blood stream, instead of being excreted in the urine together with creatinine.  But the interpretation table says the opposite of this, i.e. BUN:Cr ratio is increased.
And when there is intrarenal injury and reabsorption of BUN back into the blood is reduced due to tubular damage, then this results in greater excretion of BUN in the urine.  Which leads to a higher BUN:Cr ratio in the urine.  But the interpretation table says the opposite of this.  —Preceding unsigned comment added by 65.92.103.211 (talk) 22:51, 2 June 2010 (UTC)
thread_title:  Mistake in Interpretation? 

message: The BUN:Cr and Urea:Cr ratios are based upon serum (blood) values and not urine measurements.  —Preceding unsigned comment added by Harrisd5917 (talk • contribs) 01:21, 4 June 2010 (UTC)
replies: text: I've added that to the text. Dr. Vogel (talk) 16:54, 21 February 2023 (UTC)
thread_title:  clarification BUN:Cr and Urea:Cr 

message: Can we get some more clarification and research for this section? The argument that high protein intake won't lead to elevated BUN is false I believe. Also, if breakdown from upper GI bleed doesn't elevate BUN but its due to pre-renal state, then why doesn't lower GI bleed also elevate BUN?  — Preceding unsigned comment added by Smodtactical (talk • contribs) 19:30, 2 July 2012 (UTC)
thread_title:  BUN increase with upper GI bleed 

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