Talk:Antipruritic

message: Is there another (better) source about calamine's lack of anti-itch properties? I am not very convinced by the IHT reference about calamine. I mean, not only is it not primary literature, it's third-hand: "In 1992, the L.A. Times reported that the FDA said that..." I also cannot find any data by the FDA on calamine in 1992, except for a speicific product recall of phenolated calamine. Is there anything more convincing out there? In the mean time, I'll place a disputed tag and cite primary literature claiming antipruritic properties of Calamine. Ideally there would be an actual controlled study and scientific article, but I would be content with a statement from the FDA itself. --chodges 04:47, 18 July 2007 (UTC)
replies: text: I'm tempted to remove all mention of this IHT article unless a source can be found that you'd consider better. Personally, I find Calamine works quite a lot better than e.g. Lanacane at removing itching entirely. It certainly might not treat the underlying condition (unless it's just mechanical damage from constant scratching), but as far as "antipruritics" go, this is about the best I know, and it'll take more than an IHT article to convince me that I've been hallucinating about its effectiveness for 30 years. AllGloryToTheHypnotoad (talk) 22:02, 20 January 2008 (UTC)
replies: text: I did some digging and located what appears to be the original 1992 FDA report, declaring that they do not consider calamine location to be "generally regarded to be safe" for use in OTC drug products for insect bites/stings or poison ivy/oak/sumac (http://www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/DevelopmentResources/Over-the-CounterOTCDrugs/StatusofOTCRulemakings/ucm078437.pdf). However, this seems to have changed at some point, as calamine is now listed as approved for OTC use as a external anesthetic for insect bites/stings and poison ivy/oak/sumac (http://www.fda.gov/downloads/AboutFDA/CentersOffices/CDER/UCM135688.pdf), and is also specifically mentioned in a FDA consumer report as a suggested treatment for poison ivy and similar (http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm049342.htm). - Pacula (talk) 17:55, 28 April 2011 (UTC)
thread_title:  Calamine lotion not clear yet 

message: The genus Rumex is, according to that article, used as a remedy for nettles.  Are they anti-pruritic?  Has this been confirmed by studies? -- Beland 00:06, 1 August 2007 (UTC)
replies: text: Pubmed has nothing with Rumex and nettles, but I found this:  --Arcadian 03:29, 1 August 2007 (UTC)
thread_title:  Rumex 

message: Intelligent people know that mosquitos don't "sting". They inject anticoagulant proteins to drink blood; that create an inflammatory reaction. Ammonia is toxic and would not reduce the reaction to these proteins. Bee and ant (genus formica) stings, and Nettles, contain [Formic Acid] which is neutralized by Sodium Bicarbonate solution.
The use of Sodium Bicarbonate (baking soda) baths, oatmeal baths, and Zinc Oxide seems to be to adsorb toxic substances from the skin surface as the urushiols (dihydroxy alkyl phenols from [Poison Ivy]). 
Several over-the-counter medications now contain Zinc Acetate in place of Zinc Oxide.
Shjacks45 (talk) 05:48, 5 February 2012 (UTC)
thread_title:  Ammonia. Really? 

message: Any value in covering the use of systemic corticosteroids or new drugs like oclacitinib (Apoquel) that interfere with the itch pathway? horsedreamer 19:45, 31 October 2015 (UTC)
thread_title:  Prescription Antipruritics 

message: Newly created article on the same topic of anti-itch medications, but with better content. User:力 (power~enwiki, π, ν) 16:18, 15 May 2021 (UTC)
replies: text: I support a merge, but don't have time to tackle it at the moment.  If no one else does it in the next week or so, I'll do it then.  Reba16 (talk) 23:01, 18 May 2021 (UTC)
replies: text:  just in case you're in the mood. Klbrain (talk) 18:15, 4 October 2021 (UTC)
replies: text:  Klbrain (talk) 09:00, 5 September 2022 (UTC)
thread_title:  Proposed merge of [[Abirritant]] into [[Antipruritic]]