Talk:Hypersensitivity

message: I came here assuming this is a term widely used to describe a form of mental disorder, but can't find anything relating to it. Is that because it's not an "official term"? Thanks. 79.238.218.188 (talk)  —Preceding undated comment added 20:13, 20 June 2010 (UTC)
thread_title: mental disorder?

message: i was to believe that an immune response that targetted the bodies own tissues was an autoimmune disease, not neccesarily a hypersensitivity reaction. perhaps it should be clearer what the relationship between the two are?
—Preceding unsigned comment added by Chaotic rach (talk • contribs) 
* Would you please cite the text that is confusing?Niels Olson 00:45, 19 April 2007 (UTC)
replies: text: It's the strange Type 5 text.  The questioner is right:  Myasthenia gravis and Graves Disease are B-cell mediated autoimmune diseases.  An "allergy" (as the term is used by the average person) requires a non-self component for the antigen. WhatamIdoing 01:39, 7 June 2007 (UTC)

text: Unfortunately, the colloquial use of allergy simplifies a more complex immunological reality.  An "allergy" to peanuts, for instance, is mediated by a Type I hypersensitivity mechanism, whereas an "allergy" to nickel (for example in less expensive jewelry) is a delayed-type hypersensitivity (type IV).  To answer the original questioner, these hypersensitivity reactions are the mechanisms by which some autoimmune diseases cause damage.  In Myasthenia gravis and Graves Disease, antibodies are produced to the acetylcholine receptor and the thyroid stimulating hormone receptor respectively.  Unlike most Type II hypersensitivities, these diseases don't cause the death of the cells, rather depletion of the receptor (in MG) or activation of the receptor (in Graves).  Thus, they are sometimes classified as type V, to acknowledge the fact that they do not cause the death of cells via ADCC.  This being the case, can you suggest any changes that might help to clarify the article?  Jprawn 20:34, 9 June 2007 (UTC)
thread_title: Type 5?

message: It was my understanding that farmer's lung (hypersensitivity pneumonitis) was classically thought to be a type III hypersensitivity, although more recent research (Allergy Asthma Proc. 2007 Jan-Feb;28(1):25-7) has shown type IV hypersensitivity as having an important role.  Should the link to farmer's lung be moved down to either type III or type IV?  Jprawn 19:16, 17 May 2007 (UTC)
thread_title:  Is farmer's lung really a type II hypersensitivity? 

message: I thought there is a distinction btwn type 2 cytotoxic and noncytotoxic.  Please confirm.  —Preceding unsigned comment added by Tkjazzer (talk • contribs) 20:55, 11 November 2007 (UTC)
thread_title:  type 2 cytotoxic vs noncytotoxic 

message: Shouldn't Fibromyaliga be listed under this type? I know there is still a lot that is unknown about Fibromyalgia, but it seems this would be the appropriate category to list it as it does cause hypersensitivity to temperature and touch. Angelmunchkin04 (talk) 19:05, 22 January 2008 (UTC)
thread_title:  Type 3 - immune complex 

message: In the article (Rajan TV (July 2003)) granuloma was described as type V hypersensitivity! Nothing about autoimmune reactions! Could anybody refer some adequate article, please?!  —Preceding unsigned comment added by 134.93.178.79 (talk) 00:41, 23 February 2011 (UTC)
thread_title:  Type V reference 

message: Im an intern Immunotechnologist and during my studies I have heard that they have created a Hypersensitivity type VI group.
 still being a delayed T-cell dissorder but specificaly with CD-8 and NK cells removing them from Hypersensitivity type IV group.
 This would specificaly effect; a poison ivy contact dermatitis as it is a CD8 regulated respons as the lipid component is presented by MHC 1
 (contact dermatitis' regulated by CD4 would still be Hypersensitivity type IV) but as well as tissue transplant 
 rejections due to tissue type as it is regulated by NK and CD8 cells  
(due to blood group would be Hypersensitivity type II, and chronic would be Hypersensitivity IV due to CD4 action).
 Is this completely false or is it true, and can you recomend any relivant articles?
 and if it is true is this page not out dated.
 Thanks  
(and as far as I know farmers lung is a Hypersensitivity type III, but can move into a chronic phase forming Granulomas and becoming a Hypersensitivity type IV, not a type II as this disease is mediated by IgG and IgM not IgE)
If i want to remain only with th imunity and hence want abstain medicine its possible for me but am needing a very good ness of a will power . I am needing to keep a good contact with immunity which i am born with . Thus i could keep th metabolism not needing to urge for activity .
...... In case someone other than my own self reads this then i humbly request to consider th fact that i am not a man of medicine rather its just common-sense about some facts which my self got confirmed by my personal experience . So i may using this rest fullness of metabolism in sense other than it stays in its own particular ...... Whatever .
Thatsit . Here by me . I have created this page basically for my own reasoning .  — Preceding unsigned comment added by 99sad (talk • contribs) 18:17, 3 November 2012 (UTC)
thread_title:  Hypersensitivity type VI  ?? 

message: I have added the medref template to this article. There was a bit of an edit war going on the main page of this article and I have removed those comments from the main page. Those discussions should occur on the talk page and should never make their way to the articles main page.
For such a fundamental concept in immunological research it is completely unacceptable that this article only has ~6 references of which 3 are text book references and none of the research references are newer than 2003. This article requires considerably more research literature referencing whether that is from research or review articles in the literature. For the editor that added Tau et al.: that is a text book citation and thus does not alone meet the burden of evidence to full support your statements. –TheIguana (talk) 18:14, 28 September 2013 (UTC)
replies: text: Just to say that recent research articles are rare on this topic been looking but not coming up with much.McortNGHH (talk) 20:21, 29 May 2016 (UTC)
thread_title:  Additional Citations Needed 

message: , this is an extremely important article which needs a cleanup. I'm not quite sure if there is a formal way of making this request, but would it be possible to please have a WP:MED task-force give this article the TLC it deserves? Thanks in advance! Vitreology talk 11:45, 23 September 2019 (UTC)
replies: text: One can ask at WT:MED. Doc James (talk · contribs · email) 16:59, 23 September 2019 (UTC)
thread_title:  Articles needs some attention 

message: I believe the article needs to have separate subtopics describing each hypersensitivity class, just having the table may not be enough to clarify certain information. The article will improve with details regarding the pathophysiology of each hypersensitivity class and how to differentiate different classes with similar symptoms. This will push the article from the start class to a higher class.
: Also there is nothing mentioned about diagnosis and treatment options for each hypersensitivity.
: Addition of citations where needed.
: Addition of link to words that have not been linked to other wikipedia pages for better understanding by people not in the medical field.
: The article can benefit from the addition of pictures.
: Also, it needs to be updated to the latest information. JanD20 (talk) 06:11, 23 June 2021 (UTC)
thread_title:  Subtopics on the hypersensitivity classes required 

message: What does it mean? 82.39.97.99 (talk) 15:54, 18 January 2023 (UTC)
thread_title:  Hypersensitivity