Talk:Agmatine

message: This article was automatically assessed because at least one WikiProject had rated the article as stub, and the rating on other projects was brought up to Stub class. BetacommandBot 07:51, 10 November 2007 (UTC)
thread_title:  WikiProject class rating

message: I notice a series of edits to this article by Dr. Gad M. Gilad that substantially changed the presentation and content of the article. Dr. Gilad is, no doubt, an authority on the subject; but he holds several patents, and is also the CEO of a company that markets agmatine as a dietary supplement.
I have not reviewed the changes made, and am not making any statement to the effect that Dr. Gilad is untrustworthy. However, given his material stakes in this, I am asking for others to check the diffs and citations to be sure that the article's integrity is preserved. In particular, be on the lookout for the removal of "negative" results (e.g. papers whose conclusions question agmatine's safety) or any rewording-to-disarm. 
Again, I have not reviewed the changes. This kind of review is simply warranted whenever a party with financial interest in a substance edits an article about that substance.
νημινυλι (talk) 00:16, 17 June 2014 (UTC)
replies: text: Briefly scanning the article, my impression is that these are good-faith edits. I think they still deserve review by some experienced editors, given the circumstances I mentioned above. νημινυλι (talk) 00:29, 17 June 2014 (UTC)
replies: text:  Red flag: under the heading "Utility as a nutraceutical," notice the sentence (sans citation) "However, the sulfate salt of agmatine is now available as a safe and effective nutraceutical for neuropathic pain." This sort of statement is why I am on the alert. Dr. Gilad sells this product, so I am not sure the broad phrase "safe and effective" should be allowed here without some kind of citation. νημινυλι (talk) 00:40, 17 June 2014 (UTC)
replies: text:  Since the statement in question was tagged with citation needed for a month, and in light of the above, I have removed it. νημινυλι (talk) 19:33, 16 July 2014 (UTC)
thread_title:  Recent edits by Gad M. Gilad, Ph.D. (May-June 2014) 

message: Thus will trim the primary ones. Doc James (talk · contribs · email) (if I write on your page reply on mine) 03:07, 24 June 2014 (UTC)
thread_title: We need secondary sources

message: There are a few issues. One is that the refs need to be formatted properly per WP:MEDHOW to make it easier for others to verify. Additionally it is unclear which ref supports much of the research section. Doc James (talk · contribs · email) (if I write on your page reply on mine) 05:59, 3 September 2014 (UTC)
thread_title: Suggestion by [[User:Gmgilad]]

message: Dear James,
Please check this new revision.
Gmgilad (talk) 23:17, 3 September 2014 (UTC)
replies: text: It is unclear which ref supports most of the research section. Doc James (talk · contribs · email) (if I write on your page reply on mine) 07:26, 4 September 2014 (UTC)
replies: text: No it is not okay. I cannot follow what you are getting at. There is no need to repeat it all here. Doc James (talk · contribs · email) (if I write on your page reply on mine) 02:43, 3 October 2014 (UTC)

text: Ref 2 does not appear to work. As a number of refs not properly formatted. Doc James (talk · contribs · email) 04:13, 19 November 2014 (UTC)
thread_title:  Agmatine - Suggested new revision (09-03-2014) Gad M. Gilad 

message: We're witnessing a misuse of Wikipedia to promote a commercial venture by an editor with a huge COI. There is massive violation of MEDRS, so this must stop. See interview with Gad Gilad.
Doc James has done an admirable job in cleaning up this mess. -- Brangifer (talk) 04:24, 19 November 2014 (UTC)
replies: text: Thanks BullRangifer. Extra eyes appreciated. Doc James (talk · contribs · email) 04:34, 19 November 2014 (UTC)

text: At the top of this page you'll see some colored boxes of information. The bottom one pertains to you. Please read the pages linked there and then come back here, but not before then. There is a lot you need to learn about how we do things. This isn't your personal website. We edit collaboratively, and you don't get to just write a new article which suits your purposes. So, read those links and I think you'll come back with a better understanding of what we mean by COI. (It basically means that you should avoid editing the article, and only comment on this talk page, with few exceptions.) -- Brangifer (talk) 05:56, 19 November 2014 (UTC)
thread_title:  Misuse of article for promotion 

message: "Agmatine is a natural substance that our bodies produce everyday, but if you are a weight trainer, you may want to consume 1.5g of agmatine 30 minutes prior to the exercise in order to effectively gain strong and high­quality muscles.Choueiri, Richard. "Best Bodybuilding Pre-Workout Supplements."About.com Sports. N.p., 10 Mar. 2015. Web. 03 Mar. 2016. Many researchers claim that agmatine’s cellulotoxic is very low and therefore has no side effects; however, some people who consume agmatine show negative side effects, including diarrhea and vomit.우수. "[혈관확장] 아그마틴(Agmatine)." Monsterzym. Monsterzym, 30 Oct. 2013. Web. 2 Mar. 2016."
First source is not suitable. No idea what the second source is. Doc James (talk · contribs · email) 20:10, 15 March 2016 (UTC)
thread_title: Ref

message: looks like there is debate how exactly agmatine is made in the body. genes /enzymes involved are arginine decarboxylase (ADC), AZIN1, AZIN2, OAZ1. OMIM has data on all of them and links to the studies. I looked through them but not completely sure what is going on. It would be good to have a section on its bio synthesis if someone knows enough about it to write a section on it. I don't. Meel11223 (talk) 22:14, 14 January 2019 (UTC)
thread_title:  agmatine enzymes biosynthesis 

message: I can't find any studies which claim Agmatine directly affects the serotonin receptors.  Should the article be amended to clarify this, or is there something I'm missing?  — Preceding unsigned comment added by 98.207.94.80 (talk) 01:43, 10 September 2020 (UTC)
thread_title:  Serotonin Receptor Effects