Talk:Cofactor (biochemistry)

message: If anyone has time, the  template would really benefit from your expertise.  Thanks! :) Willow 19:11, 27 January 2007 (UTC)
thread_title: Template help

message: Just FYI, here are examples of articles using the term in the broader sense I indicate in this section:
http://mcb.asm.org/cgi/content/abstract/22/6/1626
http://www.ncbi.nlm.nih.gov/pubmed/15860367
http://www.nature.com/nature/journal/v398/n6730/full/398824a0.html
Jbening (talk) 00:48, 16 October 2008 (UTC)
replies: text: To see a clearer example of the cofactors in succinate dehydrogenase, refer to :File:Succinate Dehydrogenase 1YQ3 Electron Carriers Labeled.png. The heme group is in the transmembrane domain of this complex. Would you prefer this image in the article? Tim Vickers (talk) 16:41, 9 March 2009 (UTC)

text: OK, done! Tim Vickers (talk) 20:34, 9 March 2009 (UTC)

text: Added to lead. Tim Vickers (talk) 16:35, 11 March 2009 (UTC)
thread_title: Non-enzymatic cofactors

message: I deleted the figure, because I do not what it shows, but I clearly know that succinate dehydrogenase is the typical example of an oxidoreductase that is NOT a heme protein, but an iron suflur protein.
This can be verified in any biochemical textbook.
Lulubou (talk) 09:42, 9 March 2009 (UTC)
replies: text: To see a clearer example of the cofactors in succinate dehydrogenase, refer to :File:Succinate Dehydrogenase 1YQ3 Electron Carriers Labeled.png. The heme group is in the transmembrane domain of this complex. Would you prefer this image in the article? Tim Vickers (talk) 16:41, 9 March 2009 (UTC)

text: OK, done! Tim Vickers (talk) 20:34, 9 March 2009 (UTC)
thread_title: Biochemical stupidity

message: Great !. Good idea to merge the articles on cofactors, coenzymes and prosthetic groups. I have not yet looked at the details, but the article looks great and well structured. 
I am just wondering, if those readers that are redirected from the terms ”coenzyme” and ”prosthetic group” mightl not be frustrated when they do not see these terms immediately. Maybe it would be good to add them in the title that could run : Cofactors, coenzymes and prosthetic groups. It would be nice if the terms "coenzymes" and "prosthetic group" already appear in the introduction with a small explanation.
Lulubou (talk) 11:38, 11 March 2009 (UTC)
replies: text: Added to lead. Tim Vickers (talk) 16:35, 11 March 2009 (UTC)
thread_title: Merger

message: This article uses the term thiamine diphosphate (ThDP) and the article to which it links is titled thiamine pyrophosphate (TPP), but acknowledges the alternative term . I know it is a matter of in which enzymology circles you roam, but should we be internally consistent and call it TPP in this cofactors article? The problem I have with thiamine diphosphate is some people (a rather famous enzymologist included) abbreviate it TDP, and that gets confused with the thymidine diphosphate. Pdcook (talk) 15:38, 9 October 2009 (UTC)
replies: text: You're right, I'd prefer TPP as well. Tim Vickers (talk) 17:29, 9 October 2009 (UTC)
replies: text: Since there is no dissent, I'm going to change it to thiamine pyrophosphate.Pdcook (talk) 17:55, 13 October 2009 (UTC)
thread_title:  The thiamine cofactor 

message: ApoC-II and apoA-I are protein cofactors for lipoprotein lipase (LPL) & lecithin-cholesterol acyltransferase (LCAT), respectively. I just linked the word "cofactor" in that article to this article, but the first thing this article says is contradictory to the function of these two apolipoproteins. What's up? Dcs002 (talk) 23:24, 18 July 2010 (UTC)
replies: text: The strict definition is non-protein, but some people use the word more loosely. I'd just call these proteins enzyme activators myself, since their presence isn't essential for enzyme activity. Tim Vickers (talk) 00:50, 19 July 2010 (UTC)
thread_title:  Cofactors are non-protein? 

message: Several glutathione analogs are not yet discussed, including mycothiol, bacillithiol, and trypanothione.
Chlorophyll deserves to be discussed as a cofactor.
The page also should mention that a number of cofactors (e.g. heme) exist in a variety of forms.  — Preceding unsigned comment added by Daniel haft (talk • contribs) 16:09, 19 March 2012 (UTC)
thread_title:  Cofactors not yet discussed 

message: Either one must be false. Please correct. -- 78.50.190.114 (talk) 16:53, 12 December 2012 (UTC)
thread_title:  "Cofactors are inorganic" vs "five organic cofactors". 

message: Substituted at 11:59, 29 April 2016 (UTC)
thread_title: Assessment comment

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thread_title:  External links modified 

message: Where do "protein-derived cofactors" fit in the types of cofactors in the introduction? kupirijo (talk) 13:00, 3 October 2023 (UTC)
thread_title:  Protein-derived cofactors