Talk:Autophagy

message: Programmed cell death says the organelles are destroyed "in a specific sequence", and I want to know what it is. —Keenan Pepper 04:17, 23 July 2006 (UTC)
replies: text: Based on the sequence of essential operations I'd guess, which might vary on the type of cell and it's current state. Them genes is pretty complex. Tyciol (talk) 17:43, 29 November 2008 (UTC)
thread_title: Auto-destruct sequence

message: The article claims there is no conclusive evidence pointing to this being a type of programmed cell death, but I had a lecture a few weeks ago by the head of a haematology research lab who claimed it definitely was. I may be wrong - she was a bit of an idiot.  —Preceding unsigned comment added by Andykinosis (talk • contribs) 03:54, 6 April 2008 (UTC)
thread_title: Programmed cell death

message: Could we have a section for diseases that are due to malfunctions of autophagy, and possible treatments for them.  Maybe Alzheimers, Parkinsons and Huntingdons diseases? Scientific American May 2008 says Rapamycin 'induces' autophagy. Rod57 (talk) 13:20, 5 October 2008 (UTC)
replies: text: [What an information-dense article!] Could aberrant autophagy result in malabsorption of nutrients in humans? Is that an example of autophagy in LRBA mutation? Thank you for your time, Wordreader (talk) 23:30, 13 March 2021 (UTC)
thread_title: Diseases and possible treatments

message: Periods of subnormal nutrition (macronutrients usually rather than micro) occurs during calorie restriction and the cutting phases that bodybuilders use. I am wondering if it would be possible to expand upon the relation of these and the higher health seen in some bodybuilders and calorie restrictors who do so in combination with a healthy lifestyle and optimal micronutrients. Tyciol (talk) 17:43, 29 November 2008 (UTC)
thread_title: Calorie restriction/cutting

message: Currently autophagy redirects to autophagy (cellular) anyway, so how come we don't move this to autophagy? I would see the 'cellular' in parenthesis as only necessary if there were some other form of autophagy that had an article, making autophagy a disambiguation page rather than a redirect. Another option would be moving this to autophagocytosis which is also mentioned here, and looks nice and fancy and all. Tyciol (talk) 17:45, 29 November 2008 (UTC)
thread_title: Redirect issues

message: So far,it's might be too early to define the function of PI3K class III in macroautophagy. The hVpS34 (PI3K Class III) has been reported to form different complexes with different partners and these complexes may play distinct roles on autophagy. In additon, the hVpS34 has also been recognized as a sensor to transduce signals from extracellular amino acids to mTOR complex I, which is supposed to inhibit autophagy.
Oremine woo (talk) 18:21, 11 April 2009 (UTC)
thread_title:  how macroautophagy is initiated is still under a big question mark. 

message: I'm always confused as to the pronunciation of Greek and Latin derived words. Is it auto-fagy or auto-fajy?  —Preceding unsigned comment added by 69.90.55.168 (talk) 02:14, 30 September 2009 (UTC)
thread_title:  Pronunciation 

message: In a medical article, the very recent references would be queried if they're not review articles.
Should the recent refs be checked for this project? RDBrown (talk) 12:18, 19 November 2012 (UTC)
thread_title: Review Articles?

message: : In the context of disease, autophagy has been seen as an adaptive response to survival, whereas in other cases it appears to promote cell death and morbidity.
A "response to survival"? How do you respond to survival? And this (presumably positive?) response we see only in the context of disease, whereas in other contexts autophage promotes morbidity? Isn't morbidity the same as disease? AxelBoldt (talk) 21:59, 29 September 2013 (UTC)
thread_title:  Strange sentence in intro 

message: Hello fellow Wikipedians,
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*Added archive https://web.archive.org/web/20110309173256/http://tp-apg.genes.nig.ac.jp:80/autophagy/ to http://tp-apg.genes.nig.ac.jp/autophagy/
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thread_title:  External links modified 

message: I have changed the parkinson's disease section to become more general as it is known that autopahgy is linked to a range of other neurodegenerative diseases. Thus in hopes that this section becomes expanded in the future  — Preceding unsigned comment added by 129.241.158.85 (talk) 00:36, 3 November 2016 (UTC)
thread_title:  Autophagy and neurodegenerative disease 

message: I check pages listed in :Category:Pages with incorrect ref formatting to try to fix reference errors. One of the things I do is look for content for orphaned references in wikilinked articles. I have found content for some of :Autophagy's orphans, the problem is that I found more than one version. I can't determine which (if any) is correct for this article, so I am asking for a sentient editor to look it over and copy the correct ref content into this article.
Reference named "test":
From End-of-life care: 
From Suicidology: 
I apologize if any of the above are effectively identical; I am just a simple computer program, so I can't determine whether minor differences are significant or not. AnomieBOT⚡ 11:13, 23 June 2021 (UTC)
thread_title:  Orphaned references in [[:Autophagy]] 

message: Type 2 diabetes is more related to insulin resistance and not insulin secretion.
From the article it stems that reduced insulin production leads to type 2 diabetes.
I wonder if this is mentioned in the cited source. It is behind a paywall and would be great if someone with access could check it.
In general more info on crinophagy is needed in the article.
--Motikor (talk) 17:35, 4 January 2022 (UTC)
thread_title:  Type 2 Diabetes Connection to Crinophagy 

message: ￼o mention of longer term water only fasting despite numerous studies showing it initiates autophagy. 
https://scholar.google.com/scholar?hl=en&as_sdt=0%2C5&q=water+fasting+autophagy&btnG=
2A00:23C6:8499:BB01:C9D5:A319:F222:267F (talk) 21:02, 13 May 2023 (UTC)
thread_title:  Water only Fasting