Talk:Thrombosis

message: I added the section called "Dangerous?" to differentiate between the type of thrombosis that can kill you vs. those that are innocuous but more likely to occur. My experience was that I had a superficial thrombosis which was not dangerous but all the information on the web regarding thrombosis/blood clots goes pretty quickly to "stroke, pulmonary embolism, heart attack, DEATH". So I blew an ER visit on finding out the difference between the two. Thought this would be helpful to people who will end up here to allay fears about the harmless versions. I put it near the top so that people who are trying to self diagnose would find it quickly. Hope I'm conforming to conventions and not stepping on any toes.   — Preceding   unsigned comment added by Bthegoodwin (talk • contribs) 00:42, 2 August 2011 (UTC)
thread_title: Added Dangerous? Section

message: I had a blood coming out of my penis while ejaculating....does anybody know what that is???????
:Well, this page is about clots, not fresh blood. Please see your own doctor, and do not ask these questions in a public forum where every crank can give you bogus advice. JFW | T@lk 08:02, 22 Jun 2005 (UTC)
thread_title: med adv

message: I had surgery (lumpectomey w/ node removal) for breast cancer on 12/20/06.  I am now in radaition treatments.  Today they discovered two blood clots in my arm (the same as the side of breast cancer and node removal).  They are treating me with herceptin(?) and coumadin.  So many people have told me to be very careful and not break the blod clots as they could cause either a heart attack or brain anyerism(sp), both of which could be fatal.
Is this really true?  Is this really that serious?
maximinkMaximink 08:05, 22 February 2007 (UTC)
replies: text: Hmm... It is always good, when the patient tries to understand, what his MD is doing... If u doubt, that u understood ur doctor of medicine correctly (or even that he understood ur condition correctly), u should seek further counseling with ur family doctor (or if necessary with another MD)... If ur health insurance does not cover a second/third opinion, u can possibly ask the local health authority for assistance... --Homer Landskirty 18:42, 5 March 2007 (UTC)
thread_title:  Arm Clot 

message: Venous thrombosis less common in those with participate in sports  JFW | T@lk 06:43, 15 August 2007 (UTC)
thread_title:  Sports 

message: I do not think a Virchow's Quadrate exists. I've only heard of the Virchow's Triad. Can anyone explain?  —Preceding unsigned comment added by Drteoh (talk • contribs) 19:27, 9 November 2007 (UTC)
thread_title:  Virchow's Quadrate

message: I doubt that Reginald VelJohnson was the one that coined the term, considering he is an actor that was not alive during the year listed.JoeyFNK (talk) 02:58, 27 December 2007 (UTC)
thread_title:  Vandalism 

message: Malignancy is more common in VTE, with the usual suspects standing out: ovary, pancreas etc http://www.blackwell-synergy.com/doi/abs/10.1111/j.1538-7836.2008.02928.x JFW | T@lk 08:38, 16 April 2008 (UTC)
thread_title:  Malignancies 

message: This vital article (I have changed the importance to "top") is presently in a ghastly state, which is always a good thing when MCOTW comes crashing in with power tools.
* We need to avoid going into individual thrombotic conditions, as they are suitable dealt with on their own pages. We do need to mention them all, and make the important distinction between arterial and venous thrombosis and atherothrombosis (which are different disease processes), micro- and macrovascular thrombosis and red and white clots.
* Careful delineation with platelet and coagulation is needed. A good general source is needed that focuses on the interplay between vessel wall, platelets, coagulation proteins and fibrinolysis, rather than one particular aspect of the disease process.
* There is not a word on diagnosis and treatment yet. For diagnosis, some generalisations about FDP and D-dimer and widely used imaging modalities are probably sourceable. For treatment, there are piles and piles of high-quality reviews and guidelines available.
* I'm not sure if the WP:MEDMOS outline should be adopted.
Let's see how this one goes. JFW | T@lk 06:28, 13 July 2008 (UTC)
replies: text: Sorry, FDP=? —KetanPanchaltaLK 12:51, 14 July 2008 (UTC)
replies: text:  FDP=Fibrin degradation products. It's a marker of thrombus turnover. Axl (talk) 18:02, 22 July 2008 (UTC)
thread_title: MCOTW summary

message: http://asheducationbook.hematologylibrary.org/cgi/content/full/2005/1/1 - is an excellent introduction on venous thrombosis by Rosendaal. JFW | T@lk 22:49, 13 July 2008 (UTC)
thread_title:  Background reading 

message: I think the article would be improved with some expansion to the section on Causes.  The serpinopathy section of another article claims that "Well characterised serpinopathies include emphysema, cirrhosis, thrombosis and dementia." and provides a citation.  I suspect there may be other causes as well, but was surprised to find this article mentioning nothing on it at all about the serpin connection that has apparently now been established.N2e (talk) 19:06, 19 July 2008 (UTC)
replies: text: Following on to your edits to cirrhosis and Talk:dementia: I think you misunderstand the comment on the serpin article. It refers specifically to the condition antithrombin III deficiency, which is indeed the result of a serpin deficiency and does indeed predispose to thrombosis. JFW | T@lk 13:57, 20 July 2008 (UTC)
thread_title:  Another "Cause" to consider 

message: Couldn't be more timely. Free full text --Steven Fruitsmaak (Reply) 19:29, 22 July 2008 (UTC)
replies: text: This is a summary of almost 1000 pages of guidelines (TOC of Chest supplement). What a monster effort that must have been. Ridiculously, apart from the summary these articles are not actually available free. I am in full agreement with the respondent in the E-letters (URL) who feels that this is a ridiculous situation that will interfere with the effective implementation of said guidelines. JFW | T@lk 06:28, 25 July 2008 (UTC)
replies: text: On the other hand, the first recommendation on prophylaxis is: hospitals should develop their own guidelines. --Steven Fruitsmaak (Reply) 20:49, 25 July 2008 (UTC)

text: In the UK we are patiently awaiting NICE to extend their guidelines to medical patients in addition to surgical ones. JFW | T@lk 22:08, 27 July 2008 (UTC)
replies: text: You mean you are continuing the epidemic... --Steven Fruitsmaak (Reply) 08:51, 29 July 2008 (UTC)

text: No, we are presently working on the Chief Medical Officer's interim recommendations. JFW | T@lk 22:01, 18 August 2008 (UTC)
thread_title:  New guidelines are here! 

message: Having suffered a VTE and being overweight or obese almost doubles the risk that it will happen again: http://archinte.ama-assn.org/cgi/content/abstract/168/15/1678 JFW | T@lk 22:00, 18 August 2008 (UTC)
thread_title:  Weight 

message: When I was a child, I used to read a lot of "real life medicine" stories and one which stuck out involving a lady who exercised compulsively (I believe the story involved her substituting exercise for prior over-eating) and the sheer number of thigh exercises she did lead to a thrombus in her thigh which started blocking all blood flow. I thought I remember a similar story in the "The Dark Side of the Moo" article on Chung Moo Quan, but it turns out that was a case of compartment syndrome. Anyone with more knowledge know whether it's plausible that the first case was indeed an exercise-related thrombus? I'm afraid the only other case I remember clearly involved a girl overdosing on a particular type of carotene supplements which were being marketed as FDA-approved tanning pills (They were FDA approved, but only for food dye and at much lower dosages). -67.171.65.251 (talk) 02:23, 17 March 2011 (UTC)
thread_title:  Excessive Exercise - possible cause? 

message: I note the following:
* wikipedia.org/venous_thrombosis goes to its own article
* wikipedia.org/arterial_thrombosis redirects to "thrombosis" article
I know the difference between "venous" (in the vein) and "arterial" (in the artery).
This article contains information about both "venous" and "arterial" thrombosis. It seems to me that this would be a better structure:
* split off the "venous thrombosis" parts of this "thrombosis" article and merge with the existing "venous thrombosis" article
* new "wikipedia.org/wiki/arterial_thrombosis article which includes the arterial-specific portions of this article
* the stripped-down "thrombosis" article should remain at wikipedia.org/wiki/thrombosis to serve as an overview with links to the venous_thrombosis & arterial_thrombosis articles  — Preceding unsigned comment added by 67.230.129.115 (talk) 19:00, 20 September 2011 (UTC)
thread_title:  Mixed bag: venous and arterial articles 

message: The link to hypoxia should probably be more correctly linked to ischemia .  — Preceding unsigned comment added by Taxtropel (talk • contribs) 20:15, 15 February 2012 (UTC)
thread_title:  Hypoxia 

message: By ISTH doi:10.1111/jth.12725 JFW | T@lk 19:24, 16 September 2014 (UTC)
thread_title:  Recommendations of prevention in cancer outpatients 

message: doi:10.1182/blood-2016-05-718114 JFW | T@lk 11:21, 12 August 2016 (UTC)
thread_title:  Leukocytes are not bystanders 

message: Some content was added about folic acid deficiency being a risk factor for thrombosis by elevating homocysteine. Firstly, it was added to the opening paragraph on the pathogenesis, whereas hyperhomocysteinaemia still fits within Virchow's triad. Secondly, I am not aware of good epidemiological evidence that folic acid deficiency is actually associated with increased thrombosis risk. Biochemical plausibility does not mean real world association. JFW | T@lk 08:59, 2 December 2016 (UTC)
thread_title:  Folate