Talk:Rhodopsin

message: Hi,
This is a good start on the rhodopsin page.  Someone needs to expand it a bit (i.e. add 11-cis in front of the first retinaldehyde and add all-trans in front of the second.  More important, rhodopsin absorbs green light (500 nm) not purple.  Purple is not even a color of light.  It results from the eye simultaneously registering red and blue light, which is what you get when you remove the green light from the mixture of colored light we call white.  Rhodopsin looks purple because it absorbs green.  It would also be good to add that there are lots of invertebrate rhodopsins besides the vertebrate ones.  Otherwise, my 25 years of research experience with rhodopsin says you have done an excellent job.
Best regards,
James W. Lewis
:I don't know why Emperorbma believed that rhodopsin absorbed the most at purple.  If I understand the descriptions right, rhodopsin is really crimson (purplish-red), which makes sense since its peak absorbance is at a hue I call algæ (green-cyan), at 498 nm.  Why can't I find a photograph of rhodopsin? lysdexia 01:55, 23 Nov 2004 (UTC)
thread_title: Page expansion

message: Online vitamins guide  was moved to vitamins article. Biophys 03:32, 14 November 2006 (UTC)
thread_title: Links

message: I think metazoan might not be "good style". Most readers will need to follow the link in "is expressed in metazoan photoreceptor cell" to learn that it is animal. So please don't be so sharp that others bleed. 91.152.95.139 (talk) 08:54, 8 May 2008 (UTC)
replies: text: I agree though I wouldn't call the practice of using unnecessary jargon at all competent. 'Metazoa' is best reserved for when a distinction has to be made with Protozoa. When the comparison is with bacteria, 'animals' will do. --Bendž|Ť 11:03, 8 May 2008 (UTC)
thread_title: Overcompentence?

message: :Rhodopsin [...] is responsible for [...] the formation of the photoreceptor cells
Really? I would have guessed that the photoreceptor cells are responsible for the formation of rhodopsin. How does rhodopsin cause the photoreceptors to spring into existence? AxelBoldt (talk) 03:30, 10 March 2009 (UTC)
replies: text: You are correct. Intro sentence has been edited accordingly.Biolprof (talk) 01:59, 20 May 2012 (UTC)
thread_title:  Intro sentence 

message: Hi everybody!
Why is there picture of SRII, which is of course retinal-bound seven-helical transmembrane protein, but it is bacterial and not GPCR?
--VGmonster (talk) 13:51, 16 June 2009 (UTC)
thread_title:  Picture on the right of the page 

message: The current version of the "Bleaching" section contains no relevant information and consists almost exclusively of factual errors.  Just a few examples:
# The section refers to "the threshold".  What threshold?  Rhodopsin is activated by a single photon of light.  Photon absorption is a quantum event lacking a threshold.  If the section refers to psychophysical experiments, then they have nothing to say about the photobleaching of rhodopsin.  
# The rest of the section describes an unrelated and unreferenced psychophysical experiment.  The properties of photoreceptors and rhodopsin are measured more directly with single-cell recordings, patch clamp recordings, and other electrophysiological techniques.
# What is "the vibrational energy derived from light"?   
# The section states that photoreceptors convert energy of light into electricity and pass it to bipolar cells.  This description is inaccurate in several ways.  First, photoreceptors form chemical synapses, not electrical synapses, with bipolar cells. Glutamate is used as neurotransmitter. Photoreceptor cells do form electrical synapses between each other, but not with bipolar cells.  Second, photoreceptors do not "convert" the energy of light into electricity.  The energy of the phototransduction chain comes from metabolic processes.  In fact, photoreceptor cells are hyperpolarized by light, which means that their membrane current decreases with light exposure (in vertebrates).
# What does the electroretinogram tell us about the photobleaching of rhodopsin? The retina has multiple populations of cells with varying responses to light and no direct relationship to changes in the properties of rhodopsin can be elucidated from the ERG.
I am removing the entire section.  
Yatsenko DV (talk) 01:03, 27 July 2009 (UTC)
thread_title:  Removing the "Bleaching" section due to numerous errors and paucity of relevant information 

message: Hi. Can we add this as information or link to Rhodopsin or a related article? There are also references that state lack of exposure to blue light during the day suppresses melatonin generation at night, potentially leading to sleep deprivation. Please ensure that this information is found on Wikipedia somewhere. Thanks. ~AH1 (discuss!) 20:04, 20 July 2012 (UTC)
thread_title:  Light pollution, blue light, and visual purple (Rhodopsin) 

message: First paragraph>
'Exposed to light, the pigment immediately photobleaches, and it....' 
okay so it 'photobleaches', but to what ? (i skimmed the photobleaching wikipage)
i could guess, does it increase or reduce light transmission/reflection, or something else?? i guess it's not simple but an approximate outline would help understanding before drowning further into the article  — Preceding unsigned comment added by 78.149.14.120 (talk) 16:56, 24 May 2013 (UTC)
thread_title:  photobleaches to what ? 

message: Can't begin to tell you how pleased I was to read the first paragraph and almost understand what was being said.  I knew going in that it was going to be over my head, but normally that doesn't deter me.  Wikipedia has the deserved reputation of starting out with the egghead explanation and never giving a layman's version.  I may have been partially responsible for spreading that reputation.  You guys usually do suck a this.  
However, today you surprised me.  Yeah, I still have to struggle, but I won't have to leave wikipedia to do that.  Thanks for the help!  ...and well done!deepsack (talk) 01:12, 16 May 2014 (UTC)
thread_title:  Bravo 

message: This article is conflating two different senses of the word rhodopsin.
1. any opsin + the chromophore retinal
2. a rod opsin found in jawed vertebrates (gnathostomes), used for scotopic (dark adapted) vision - the gene is known as Rh1 - the opsin is called either Rh1 or the Rh1 opsin
Definition #2 has several variants:
a) any rod opsin (coded for by the gene Rh1, used for dark-adapted vision, found only in gnathostomes, although lampreys have a close relative, RhA)
b) human rod opsin (OPN2)
Either of these two variant definitions can be with or without the chromophore (retinal), or at all stages of the visual cycle.
With the chromophore it's also calld visual purple.
There is also a family of rod-opsin-like opsins found in vertebrates. It includes the rod opsin Rh1, the blue-green cone opsin Rh2 (extinct in mammals), as well as RhA and RhB (found in lampreys) - usually indicated by "rhodopsins" (plural)
Ideally these should be two separate articles. In the meanwhile, we should at leaest clarify the difference within this article.
Zyxwv99 (talk) 00:46, 15 September 2015 (UTC)
thread_title:  Conflating definitions of rhodopsin 

message: Give two examples integral membrane proteins that form channels across the membrane animal cell 102.144.251.95 (talk) 16:06, 26 June 2022 (UTC)
thread_title:  Anatomy and physiology of farm animals 

message: — Assignment last updated by Nmneuro (talk) 00:08, 16 May 2023 (UTC)
thread_title: Wiki Education assignment: CHEM 378 - Biochemistry Lab - spring 2023