Talk:Nephron

message: The mechanisms in the loop of Henle are rather complicated. In my opinion, they are beyond the scope of this article. I will add more details to the loop of Henle article. Axl 12:00, 2 Dec 2004 (UTC)
thread_title:  Depth 

message: I have never studied this topic before and this page is light on citations but I'm questioning the sentence "Over 150 liters of fluid enter the glomeruli of an adult every day". First of all, I'm assuming this is referring to an adult human, not another species, and second, adult humans only contain about 5 liters of blood. Where is the 150 liter number coming from? Mayawagon (talk) 14:49, 6 April 2023 (UTC)
replies: text: on parle ici de l'urine primitive produite sur une journée: en une journee entière 150 litres d'urine primitive serra passé du sang vers les tubules rénal mais une très très grande majorité d'eau serra réabsorbé au niveau du tube contourné proximal et un peut au niveau du tube contourné distal ce qui explique la diminution du volume d'urine final (un humain urine moins d'un litre par jour) 2A01:E0A:524:F1C0:3D4D:A1F6:71AB:3A98 (talk) 15:47, 9 March 2024 (UTC)

text: on parle ici de l'urine primitive produite sur une journée: en une journee entière 150 litres d'urine primitive serra passé du sang vers les tubules rénal mais une très très grande majorité d'eau serra réabsorbé au niveau du tube contourné proximal et un peut au niveau du tube contourné distal ce qui explique la diminution du volume d'urine final (un humain urine moins d'un litre par jour) 2A01:E0A:524:F1C0:3D4D:A1F6:71AB:3A98 (talk) 15:47, 9 March 2024 (UTC)
thread_title:  150 liters??? 

message: The lead section of this page seems like it should be broken up between the lead section and the article body. Approaching this from a layman view, the introduction is currently disjointed and contains a level of depth better suited for later sections. Below is a proposed restructuring of the lead section excluding details I would move to the body. Wiki newbie here, so any fact checking or advice appreciated. Currently lacking in citations, as the first paragraph of the current page already seems to be. I believe some of the clarifications are answered throughout the article, but truthfully I rearranged this much so I could understand it, and the finer details can be a project for someone with a greater interest.
:The nephron is the minute or microscopic structural and functional unit of the kidney. A healthy adult has 1 to 1.5 million nephrons in each kidney. The job of each nephron is to filter blood into urine. Each nephron is composed of a renal corpuscle and a renal tubule. The renal corpuscle consists of a tuft of capillaries called a glomerulus and a cup-shaped structure called Bowman's capsule. The renal tubule has peritubular capillaries running between the descending and ascending portions of the tubule. Both the Bowman's capsule and renal tubule are composed of epithelial cells with a lumen.
:The filtration is performed through three layers: the endothelial cells of the capillary wall, its basement membrane, and between the foot processes  of the podocytes of the lining of the capsule. As the fluid  from the capsule flows down into the tubule, it is processed by the epithelial cells lining the tubule: water is reabsorbed and substances  are exchanged; first with the interstitial fluid outside the tubules, and then into the plasma in the adjacent peritubular capillaries through the endothelial cells lining that capillary. This process regulates the volume of body fluid as well as levels of many body substances. At the end of the tubule, the fluid exits as urine composed of water, metabolic waste, and toxins. 
Thespacesay (talk) 08:17, 14 June 2023 (UTC)
thread_title:  Lead Section