Talk:Infertility

message: *Can someone fact-check this statement, please?
:In other rare cases, they may each be fertile, but genetically or immunologically incompatible with one another, so that they might each be able to be fertile with other people, but not with one another.
This is my understanding, but I am not an expert in this field. Karada 13:19, 24 Jan 2005 (UTC)
thread_title: Fact checking

message: Women trying to conceive often have clinical depression rates similar to women who have heart disease or cancer 
the article needs such statement'
:It needs a source or it's out. JFW | T@lk 15:38, 30 November 2005 (UTC)
replies: text: It's got a source and it makes perfect sense. If you think it is not so, please provide evidence support for your POV. JFW | T@lk 15:49, 30 November 2005 (UTC)
thread_title: NPOV

message: Source please. This sounds like bunk created by environmentalists. Nothing else in the article - besides heredity and injury/disease - suggests reasons for worrying about male infertility in infants.  It may be a legitimate point with a scientific basis, but it's badly presented.
:I agree! Brian Pearson 18:17, 21 November 2006 (UTC)
thread_title:  Although more research needs to be done, parents may want to consider alternatives to disposable diapers for male infants.  

message: why would chromosomal abnormalities cause infertility? such as aneuploidy, kleinfelter's syndrome or even 48,XXYY syndrome, turner syndrome, robertsonian translocation, Small supernumerary marker chromosome and so on. Does having an extra chromosme prevent spermogenesis from not occurring? I don't understand how people with a trisomy (Down Syndrome) are infertile.  Raccoon Fox • Talk • Stalk 23:32, 10 September 2006 (UTC)
thread_title:  Chromosomal Abnormalities and Infertility 

message: I just came across an article called hamster test. I wondered if it was still used and if so, whether or not it could be inserted under Diagnosis and tests. Brian Pearson 18:13, 21 November 2006 (UTC)
thread_title:  Hamster test? 

message: I removed an external link from this article and received this reply on my talk page:
:Hi - Based on your request, I would like to discuss your removal of the external link Infertility Doctors & Clinics Find Infertility Doctors & Clinics in the U.S.  Based on my research of what external links should be linked, this seems like a perfect fit for the page because it is a "value-add" for the reader and it is something that can't be included in the content of the page directly (i.e. we can't list every individual infertility specialist on the site directly).  Here is the wiki article that I'm referencing for justification on why it should be linked:[External_links]  —Preceding unsigned comment added by 67.177.242.71 (talk) 15:17, 23 September 2007 (UTC)
replies: text: I'd say it was indeed a fair removal.--Christian B 21:35, 24 September 2007 (UTC)

text: funny you should ask.....I was actually just going to leave a comment about not finding that link.  I was on wikipedia a few weeks ago at work and utilized that link to contact a clinic and I was actually just coming back here to find that link b/c I misplaced it.  Having said that, I would say it is useful and should be put back on.  —Preceding unsigned comment added by Jbelle00 (talk • contribs) 00:53, 2 October 2007 (UTC)

text: There is a bit of advertising in the link, but yet I think it does more good than harm in the article. Mikael Häggström 04:59, 22 October 2007 (UTC)
thread_title:  External link 

message: Infertility affects approximately 10% of people of reproductive age, “Frequently Asked Questions About Infertility” (2006).  American Society for Reproductive Medicine. and 15% of couples. Roughly 40% of cases involve a male contribution or factor, 40% involve a female factor, and the remainder involve both sexes. 
The section and its refs fail to be specific about where this applies - USA? global? hardly. This is not the USPedia. Also at least the last ref is pretty meager. --84.159.167.79 (talk) 16:12, 12 February 2008 (UTC)
thread_title:  where 

message: I wanted to link to "sterile" to describe plants which cannot reproduce sexually and I found this should disambiguate to this page, described as: "The quality or state of being unable to reproduce; of being infertile. The term may be used of higher animals." To my dismay, however, this page is extremely non-general, talking about human infertility rather than the general phenomenon. I don't mean to criticize this page — I agree that most people searching on "infertility" are going to want to know about human infertility — but how should we resolve this? Any suggestions? Madeleine ✉ ✍ 20:53, 8 March 2008 (UTC)
thread_title:  lack of generality 

message: I have removed a number of external links that are non-notable or commercial and do not meet WP:EL. They don't contain a "little bit" of advertising; their entire websites are advertisements for their product, whether it's for a directory of doctors who pay to be listed, campaign to promote X or products tagged with little trademark signs. Wikipedia is not a directory or a list or a how to, and none of these links meet the spirit of Wikipedia's intent to provide vetted encyclopedic information -- they just promote somebody's business or cause. Flowanda | Talk 08:10, 16 July 2008 (UTC)
thread_title:  External links 

message: Comments on this section?  I've once heard that cordless phone base stations may be a possible factor in infertility as well.  Not aware of any studies for it, but at least we have some studies on mobile phones.
*Mobile phones: Studies have linked mobile phone usage with reductions in "sperm count, motility, viability, and normal morphology".   
*AC Magnetic Fields: Magnetic fields from alternating current have been linked to substandard sperm (over 1.6 mG for over six hours a day) and higher rates of miscarriages (over 16 mG). http://www.microwavenews.com/, July 3 entry Jcemcare (talk) 04:25, 12 September 2008 (UTC)
replies: text: Microwave news is not a valid source. Verbal chat 06:54, 12 September 2008 (UTC)
thread_title:  Mobile Phones and Infertility 

message: Why is there no discussion of animal sterility and hybrid sterility.  —Preceding unsigned comment added by 68.5.160.52 (talk) 23:07, 15 February 2009 (UTC)
thread_title:  This article is biased towards humans 

message: Can't heat also induce sterility in males? Here is something but I can try to find something else that's more reliable if necessary. If no one has any objections I will insert this. 71.67.115.56 (talk) 00:40, 16 April 2010 (UTC)
thread_title:  Heat Induced 

message: The definiton of subfertility isn't very clear, and it doesn't seem to be any different to 'normal' infertility. This ought to be changed. 218.215.51.144 (talk) 08:56, 12 March 2011 (UTC)
thread_title:  Sufertility? 

message: Major advances are being made in China with some success in treating infertility.  While these advances are making medical history, they are not being effectively shared with the rest of world and doctors who could use this information because they are being documented in Chinese and need to be sorted out and translated.  A meta analysis was done compiling the information that was found in the archives of Chinese medical studies.See, C. J., McCulloch, M., Smikle, C., & Gao, J. (2011). Chinese Herbal Medicine and Clomiphene Citrate for Anovulation: A Meta-Analysis of Randomized Controlled Trials. Journal Of Alternative & Complementary Medicine, 17(5), 397-405. doi:http://dx.doi.org/10.1089/acm.2010.0254 This meta-analysis was done to see if Chinese herbal medicine used in conjunction with traditional treatments would help increase ovulation and conception rates.  Less than 18 percent of women conceive within six months of utilizing clompihine citrate, human goanotrophins, or letrozole.   After six months without any success in getting pregnant, women begin to look into other alternatives to include complementary medicines. included looking into 1009 experimental studies that was narrowed down to 14 studies that met the criteria that was set by the researchers.  People have been using complementary medicine for years to help with ailments or medical issues.  It has been shown that acupuncture has been successful in helping women get pregnant.  The idea that women use Chinese Medicine to help with infertility is not new.  Utilizing a meta-analysis the researchers were able to look at Chinese herbal medicine and see if it does help increase the likelihood of ovulation and pregnancy.
Chinese medical journals are filled with important information that is not easily accessed since it has to be translated first.  This meta-analysis meticulously looked through these journals, while specifically picking out key words.  Even though they were focusing on key words they still ended up with many studies that they needed to look into further to determine if they fit the criteria for this meta-analysis.  While there are many studies looking into infertility this analysis was focused on specific studies that utilized Chinese herbal medicine.  The patients all had to struggle with anovulatory infertility, be randomly assigned within the study, one group needed to be given Chinese herbal medicine as well as clomiphene citrate, and another group just the clomiphene citrate.  Information on basal body temperature, pregnancy rates, ovulations rates, or endometrial lining was also required to be a part of the meta-analysis. As with most studies a confidence interval of 95% was required.  All of these criteria increase the strength of the study.  
A weakness with this meta-analysis is that all of the studies used were rated a one. While this is a very weak rating, there was no bias on publications or articles used since they were all rated the same.  Another weakness is that while a difference is shown with using both the Chinese Herbal Medicine and clomiphene citrate, the difference is not significant.  More studies will need to be done to look into this situation further. There is also the issue that since the data was collected from varying sources and few studies made it into the met-analysis there ended up being only a small sample size and varying control within each study. A larger study that is more controlled would be able to hopefully come up with more significant results.
This analysis in general brings to light that there are other options for women to try to have a baby.  Unfortunately there are many factors to play into conceiving a child.  The data showed an increase in the endometrial lining which is known to decrease when using clomiphene citrate alone.  This could be a reason for why pregnancy rates were a little higher for women taking Chinese herbal medicine. Since herbal remedies are not monitored by the Federal Drug Administration effective use and dosage is not known and the varying amount of each herb used in each study is not disclosed in this meta-analysis.
This meta-analysis brings up important ideas that should be researched further.  Women spend a lot of time and money trying to conceive.  Chinese herbal medicine may work in increasing the likelihood of women conceiving a child; any advances made in this field are very important and relevant to many women of childbearing age.  There is limited research on this tops and future research is required. This meta-analysis provides a stepping-stone for future studies.
Aclar060 (talk) 21:16, 13 April 2013 (UTC)
thread_title:  Research Study Making Advancements in Battling Infertility 

message: Like many health topics there are a huge number of acronyms and strange terms associated with infertility and its treatment. Any thoughts on adding a 'acronym/glossary' guide to this article or setting up a separate article 'beginners guide' type thing?
Scrumph (talk) 10:39, 8 July 2013 (UTC)
thread_title:  glossary/acronym guide 

message: It is simply not true that 30 % are due to the man and 30 % due to the woman and 40 % due to both. If you read the paragraph below it becomes obvious that an additional 20 % of infertility cases are due to low egg quality etc which has to do with the age of the female of the couple.
In the US, up to 20% of infertile couples have unexplained infertility.[28] In these cases abnormalities are likely to be present but not detected by current methods. Possible problems could be that the egg is not released at the optimum time for fertilization, that it may not enter the fallopian tube, sperm may not be able to reach the egg, fertilization may fail to occur, transport of the zygote may be disturbed, or implantation fails. It is increasingly recognized that egg quality is of critical importance and women of advanced maternal age have eggs of reduced capacity for normal and successful fertilization. Also, polymorphisms in folate pathway genes could be one reason for fertility complications in some women with unexplained infertility.[29]
  — Preceding unsigned comment added by 90.144.247.228 (talk) 16:38, 4 November 2014 (UTC)
thread_title:  Misleading statements 

message: This is the section on Immune Infertility
Antisperm antibodies (ASA) have been considered as infertility cause in around 10–30% of infertile couples.[22] In both men and women, ASA production are directed against surface antigens on sperm, which can interfere with sperm motility and transport through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and impaired growth and development of the embryo. Factors contributing to the formation of antisperm antibodies in women are disturbance of normal immunoregulatory mechanisms, infection, violation of the integrity of the mucous membranes, accidental rape and unprotected oral or anal sex. Risk factors for the formation of antisperm antibodies in men include the breakdown of the blood‑testis barrier, trauma and surgery, orchitis, varicocele, infections, prostatitis, testicular cancer, failure of immunosuppression and unprotected receptive anal or oral sex with men.[22][23]
What does it mean by accidental rape???? Someone please change this so it makes sense.  — Preceding unsigned comment added by 2601:640:4080:5960:64CA:84B6:F220:F150 (talk) 04:44, 30 May 2018 (UTC)
replies: text: In source: "For all these reasons, it may be deduced that ASA production in men and women can be associated to: a disturbance of normal immunoregulatory mechanisms, accidental rape, physical trauma, chemical trauma or iatrogenic infection in the hemotesticular 15 barrier or to a obstruction in the male reproductive ducts. 9,19,20,31 As a result, sperm are recognized as antigens 15,18,20,25,29 and humoral immune response is triggered by B-lymphocytes that release ASA. Cellular response is achieved by T-lymphocytes’ activation, the release of cytokines and complement system activation. 9,16,17,20 ASA production is the result of autoimmune response in men and of alloimmune response in women, and it is associated with idiopathic infertility in human beings."  Additional info  --Путеец (talk) 04:57, 30 May 2018 (UTC)

text: I suspect they just mean rape. The first language of the authors seems to be Spanish and the English in it is not fantastic. PriceDL (talk) 07:11, 31 May 2018 (UTC)
replies: text:   It looks like you're right. --Путеец (talk) 09:20, 31 May 2018 (UTC)
thread_title:  "Accidental rape" 

message: Sources are not up to date, the URL does not work. Vinsaaay (talk) 03:34, 18 October 2018 (UTC)
thread_title:  Society and Culture 

message: I don't think it is important to have a whole section about puberty let alone mention it anywhere in the article. The page is about the inability to achieve pregnancy 12 months after engaging in unprotected sexual intercourse with an opposite-sex partner. Most of the information is about children being pre-pubescent, which is really not necessary since children shouldn't be having sex anyway. WashyGenius (talk) 10:53, 31 August 2022 (UTC)
thread_title:  Unimportant information about puberty 

message: Sperm quality starts to decline at age 30. Does this mean his fertility is declining?
@Evope Evope (talk) 04:04, 11 May 2024 (UTC)
thread_title:  Sperm