Talk:6-Monoacetylmorphine

message: The image given on the page is only of 6-MAM, shouldn't there be an image below it or a drugbox below the first with an image of 3-MAM as well if this is the 'monoacetylmorphine' article rather than simply the 6-MAM article? Nagelfar (talk) 04:06, 27 November 2008 (UTC)
replies: text: Also, isn't the name here rather redundant? I've seen lab reports that name it as 6-acetylmorphine, calling it 6-monoacetylmorphine is saying it is only acetylated at the 6 position, but shouldn't this go without saying as it can't be acetylated twice in one position as such? Dual acetylated morphine is 3,6-acetylmorphine (heroin), which can't be monoacetylmorphine, which refers to either 3-acetylmorphine or 6-acetylmorphine, the prefix 'mono' in either name seems wholly unnecessary as used in literature if the position acetylated is given, and the only official lab nomenclature I have ever personally seen on the subject has only ever referred to the constituent direct metabolites of heroin as 3-acetylmorphine &/or 6-acetylmorphine, not 3-monoacetylmorphine or 6-monoacetylmorphine; diacetylmorphine is always 3,6. Nagelfar (talk) 16:42, 6 July 2009 (UTC)
thread_title:  Image of 3-MAM 

message: high temp, 1 mole of K-tertbutoxide in tertbutanol, the alcohol will react faster.
NOW, I must admit that my only claim is that this will PROBABLY give >50% yield, assuming no starting material was present at the end of the reaction.
thus the remaing <50% yield WILL be the other substitution product.
however, you can always simply hydrolize BACK to morphine, and run the reaction again.
now, if only they realized that the key to storage is complete dryness, not "sun dried," (must remove the water of hydration), then it would last for much longer.
hell, if they could package their product under N2, N-oxidation would be a thing of the past!  —Preceding unsigned comment added by 68.6.52.200 (talk) 08:24, 17 January 2010 (UTC)
thread_title:  selective acetylation at the alcohol 

message: Isn't 6-MAM also discovered as a very sparse neurotransmitter, naturally occurring in the human brain? It being the source for morphine found endogenously in vivo? If so, such a category should be added to this article. 216.227.117.35 (talk) 05:12, 6 November 2011 (UTC)
replies: text: If you have a source for this then yes it should be added.  Without a source it's original research or just speculation.--Doug.(talk • contribs) 14:35, 16 May 2013 (UTC)
thread_title:  Natural neurotransmitter 

message: The process used in creating black tar heroin actually leaves 6-MAM in the final product, which is one of several reasons why black tar, even when less pure, may be more potent than some powder varieties of heroin.
this should have a source, along with the "may be more potent" line.  — Preceding unsigned comment added by 71.193.218.227 (talk) 03:35, 9 May 2014 (UTC)
thread_title:  black tar heroin more potent due to 6-MAM 

message: Is 6 mam in ketamine ??? 2A01:4C8:1489:24DC:D83A:2164:CCCB:CDE9 (talk) 15:41, 6 January 2022 (UTC)
thread_title:  6  mam is it in ketamine 

message: "6-MAM can be synthesized from morphine using glacial acetic acid with an organic base as a catalyst."
(there is even a joke in "the simpsons" about what happens if you mix acids with bases.)
it would be quite a impressive stunt to acetylate anything with just glacial acetic acid. 2A02:8070:6188:2B60:0:0:0:6AFF (talk) 22:18, 29 January 2024 (UTC)
thread_title:   how should this work?