Talk:Pellagra

message: Could someone please change the sentence "Pellagra is an endemic disease located in ..." to "Pellagra is an endemic disease in"? When you say "endemic" you already imply the term located and it would be redundant to repeat it. Thanks. 85.178.31.153 ([[User 
talk:85.178.31.153|talk]]) 10:04, 4 March 2008 (UTC)
thread_title:  Endemic = located 

message: See hexachlorobenzene:
"American Pellagra was a disease affecting 250,000 people between 1900-1950 caused by hexochlorobenzene residue from new bleaching and degermination procedures for corn and wheat. Hexachlorobenzene was banned from use in the United States in 1966." --Espoo 09:07, 4 May 2006 (UTC)
replies: text: This seems to be wrong. I removed the sentence. Icek 21:19, 29 March 2007 (UTC)
thread_title:  caused by hexachlorobenzene? 

message: It tells symptoms and what is going on superfically but it never mentions whats causing these symptoms and what Pellagra actually is doing to the body. Would someone please add, or explain why it shouldn't. —Preceding unsigned comment added by 72.177.232.2 (talk • contribs) 02:39, 14 February 2007
: It's a niacin deficiency (from lack of both niacin and it's synthetic precursors). If you mean the mechanistic reasons - [eg. for scurvy, vitC deficiency leads to defects in collagen production and stability] - I'm not your guy. My textbooks all suggest they haven't actually been identified.60.226.133.172 06:18, 21 June 2007 (UTC)
replies: text: The most obvious reason is prostaglandine deficiency (Niacin triggers prostaglandine production). However there may also be other causes for the deseases. 178.197.236.220 (talk) 23:18, 16 August 2013 (UTC)
thread_title:  What's happening? 

message: The link to Rankin goes to a disambiguation page. I can't tell which Rankin it refers to. Ben (talk) 21:26, 22 March 2008 (UTC)
thread_title:  Rankin 

message: needs microanatomy/ histology images with explanation of microscopic findings of the dermatitis Tkjazzer (talk) 20:46, 25 March 2008 (UTC)
thread_title:  needs microanatomy/ histology images with explanation of microscopic findings of the dermatitis 

message: according to the site which i listed in list of eponymous medical signs under casal's collar, the disease was first described by françois thiery in 1755, by casal in 1762.  —Preceding unsigned comment added by Toyokuni3 (talk • contribs) 05:02, 11 May 2008 (UTC)
thread_title: First Described

message: Some clarification is necessary in the last three sentences in the Epidemiology section, which state "The amino acid deficiency must be balanced by consumption of other sources of protein. It was common amongst prisoners of Soviet labor camps, the infamous Gulag. It can be found in cases of chronic alcoholism."  It's not clear whether the "it" in the last two sentences refers to "the amino acid deficiency" that's mentioned in the first of these three sentences or to Pellagra itself.  --noosphere 01:36, 10 July 2008 (UTC)
thread_title:  What was common in the Gulag? 

message: I've removed death and converted the 4 D's to the more realistic and commonly used 3 D's.  Death should not be part of the mnemonic or memory aid, since failure of any vitamin, by its very nature, will cause death.  Adding death to the list is redundant and frankly fairly stupid.  Why would it be that if someone dies you then have to begin considering pellagra?  I immplore educators to change, like almost all new textbooks, to the 3 D's; indeed the referenced source uses 3 D's itself.  Cheers.--Cpt ricard (talk) 07:12, 9 February 2010 (UTC)
thread_title:  Removal of death as symptom/3 D's 

message: Mexicans created the nixtamalization process, which avoids pellagra. In fact, the lack of pellagra in Mexico and other Latin American countries lead scientists to find out that nixtamalization was a required grain treatment for corn intended for human consumption. Pallagra may be common anywhere else, maybe even the U. S., but not in Mexico.  24.44.93.16 (talk) 15:05, 9 April 2010 (UTC)
thread_title:  Pellagra is not common in Mexico 

message: Why does this article begin with the (admittedly common] misconception that niacin can be known as Vitamin B3, a point which some dietary experts would dispute today? ACEOREVIVED (talk) 23:34, 28 June 2010 (UTC)
thread_title: Is Niacin really Vitamin B3?

message: "Pellagra can be common in people who obtain most of their food energy from maize (often called "corn"), notably rural South America where maize is a staple food. If maize is not nixtamalized, it is a poor source of tryptophan as well as niacin."
This statement is wrong. Nixtamalization will do nothing to increase corn low tryptophan levels since corn is simply deficient in tryptophan in this essential amino acid. I'll correct if nobody else has any objection. 81.60.184.222 (talk) 19:32, 28 April 2011 (UTC)
replies: text: If that's true then nixtamalization just creates free form niacin in maize as in the article nixtamalization described. This should be written more clear in the articles...as you wrote. 178.197.236.220 (talk) 23:07, 16 August 2013 (UTC)
replies: text: Yeah, it looks like there isn't much Tryptophan but a lot of bound niazin in maize: http://www.google.ch/search?q=niacin+maize. Next time I cook my corn with lime. ;)178.197.236.220 (talk) 23:13, 16 August 2013 (UTC)
thread_title:  Nixtamalized maize is as deficient in tryptophan as before 

message: The Prognosis section needs work.  It does not cover the case when treatment is given, only when treatment is not given.  Are the symptoms and long-term harm reversed upon treatment or are they permanent?CountMacula (talk) 20:25, 25 August 2012 (UTC)
thread_title:  Prognosis 

message: Also in developed countries mild forms of Pellagra are much common. I know this because I suffered more than 10 years from it. It took me those 10 years how to become healthy again, to find out that I need niacin! For treatment I take 2 doses with 1,5g niacin everyday, and my chronique fatigue and also my skin problems just went away. So flushing is joyful, it's like an immun reaction and makes you healthy. I would appreciate if other people who experienced mild forms of Pellagra would help to improve this article.178.197.225.71 (talk) 11:47, 21 August 2013 (UTC)
thread_title:  Mild forms of Pellagra are much common 

message: Pellagra#United_States currently argues for the theory that corn contains niacin in the form of a hemicellulose-bound "niacytin" that can be liberated by nixtamalization. However, one secondary~tertiary source cited by the nixtamalization article, specifically FAO 1992, seems to quite clearly refute this mechanism of action for nixtamal using multiple sources. It's much more likely that the anti-pellagra action is due to a difference in the digestibility of tryptophan-containing proteins. – Section 5.2 "Lime-treated maize (part II)", Section 5.3 "Arepas", Section 8 "Improvement of maize diets"
There is, however, insufficient information on the effect of germ removal from FAO 1992. The section on Arepas seems suggest that germ removal is associated with a reduction of protein quality (and with "Chavez (1972b)", specifically a loss of tryptophan), but I doubt we can use it to say much about the Beall degerminator.
 Artoria2e5 🌉 05:30, 17 April 2024 (UTC)
replies: text: Brilliant, we should blame 81.60.184.222 for this. I am going to drink some beer, privately yell WP:NOTHUMAN out loud, and just bulldoze over all that. Yayyy! Artoria2e5 🌉 05:32, 17 April 2024 (UTC)
thread_title:  Niacytin