Talk:Staphylococcus aureus

message: I want to add more information on s. aureus biofilm since it is related to many s. aureus infections and antibiotic resistance. I am changing the biofilm section under "Role in diseases" to medical implant infections and moving the biofilm section to "Virulence factors". 
Thisaccountisforclass (talk) 15:57, 11 April 2018 (UTC)
thread_title: Biofilm

message: Could someone write something about its virulence as well? It's beta-haemolytic, however I'm not too sure what agent caused it.
In 1997, physicians were alarmed to encounter staph strains that resist even vancomycin, 
Was that really 1997? IMO more likely 2002 or so. 141.83.15.155 13:13 27 Jun 2003 (UTC).
It was in 1997. Read the literature.
----
What can I say? Whatever kills the S.U. at source in hospitals is good. Notable is that infections start in hospitals.Revise the disinfection processes instead.
--203.15.122.35 04:03, 11 Apr 2005 (UTC)
thread_title: Virulence

message: Recently, 203.61.130.245 and 203.61.124.91 have been inserting large amounts of very poor edits into this article. I feel the surest way to balance is reverting the whole lot, which is what I did.
There are many problems with the material. For one thing, the editor seems never to have heard about wikilinks. Furthermore, he/she does not state that all material inserted is from the POV of orthomolecular medicine, which may sound deceptively scientific but is considered quackery (or worse) by mainstream practicioners. If anyone disagrees, I'll retrieve the old version and hammer it into something sensible, but at the moment I feel nothing of note can be salvaged. JFW | T@lk 15:44, 13 Mar 2005 (UTC)
thread_title: Orthomolecular

message: Phenols are meant to be used as a hospital antiseptic/disinfectant to prevent the spread of G.S. given that infections are often acquired in those said places in high numbers and by extension, gyms and similar locations. I do not think there was an indication as to actual dosaging of patients with phenols to treat G.S. infections. Perhaps, the writing lent itself to misconstruction. Simply preventing the spread of Golden Staph in hospital settings and or medical equipment can greatly improve the chances of non-infection and thus bring death rates down.
A look at  hospitals' sanitary proceduresand  disinfectantsis in order I think and probably an interesting future article. 
Points taken on the notepad recommendation.
Thanks.
--203.61.124.92 15:14, 15 Mar 2005 (UTC)
thread_title:  Followed on to reply 

message: Both this article and the MRSA article seem to suggest that MRSA is more virulent than MSSA. I'm really not sure if this is correct. The only real difference between the two is the antibiotic susceptibility. The only reason why MRSA should be more virulent is because it proceeds unchecked while non-MRSA antibiotics are administered.
Is there anyone who has different experience? I think we should go for some source material. JFW | T@lk 03:02, 7 Jun 2005 (UTC)
thread_title:  MRSA, can we have a discussion 

message: The following may be of interest (the links are inefficient, but they do the job):
*Natural history of community-acquired methicillin-resistant Staphylococcus aureus colonization and infection in soldiers.
*Is methicillin-resistant Staphylococcus aureus more virulent than methicillin-susceptible S. aureus? A comparative cohort study of British patients with nosocomial infection and bacteremia.
*Nosocomial methicillin-resistant Staphylococcus aureus bacteremia: is it any worse than nosocomial methicillin-sensitive Staphylococcus aureus bacteremia?
*Staphylococcus aureus bacteremia and endocarditis.
* Comparison of the virulence of methicillin-resistant and methicillin-sensitive Staphylococcus aureus.
One of the problems with answering a question such as this is that the main drug effective against MRSA (vancomycin) is probably inferior to beta-lactam antibiotics.  Randomized controlled trials in this area are difficult.  It will be interesting to see the results after a broader experience with  linezolid.
Polacrilex 03:27, 7 Jun 2005 (UTC)
replies: text: Polacrilex, you're a star. That didn't take you long! JFW | T@lk 03:51, 7 Jun 2005 (UTC)
thread_title:  MRSA/ORSA more virulent? 

message: The article, as it curently reads, suggests that staph strains resistant to flucloxacillin and its b-lactimase group are termed MRSA just because labs happen to perform the b-lactimase resistance test with the methicillin member of the group.   However, my understanding was they are termed MRSA only because they are resistant to methicillin and with no regard for what else the strain may or not be sensitive too.   I have occassionally seen microbiology sensitivity reports for staph aureus infections indicating a MRSA strain and with appropriate sensitivites still including flucloxacillin (with which the patients were treated).  Of course I accept that most staph strains resistant to methicillin (thus MRSA's) are normally resistant to flucloxacillin too, and so this is then not normally an appropriate drug to start treatment with. David Ruben  Talk  20:53, 24 January 2006 (UTC)
thread_title: MRSA definition

message: By 1950, 40% of hospital S. aureus isolates were penicillin reisistant; and by 1950, this had risen to 80%.
Note both quoted years are 1950. If this is correct, perhaps it could be reworded? The present wording suggests an error (in my opinion).
From the cited source, [1], http://www.cdc.gov/ncidod/eid/vol7no2/chambers.htm:
Examination of more than 2,000 blood culture isolates of S. aureus... for 1957 to 1966... confirmed a high prevalence of penicillin resistance (85% to 90%) for hospital isolates of S. aureus.
I hope this is of some assistance. Apologies if the article's current statement is correct & considered satisfactory.
Thanks,
Claynoik 14:32, 23 April 2006 (UTC)
thread_title:  Possible error/confusing statement 

message: I've reverted the introductory sentence to "sometimes known as golden staph" versus the "more commonly known as" sentence; a PudMed search gives ~50,000 hits on "Staphylococcus aureus" and three (yes, 3) hits on "golden staph". -- MarcoTolo 21:21, 21 September 2006 (UTC)
thread_title: Golden Staph

message: Hi there,
I'm an engineering trying to find some facts about bacteria.  Does anyone know where can I find information about physical properties of bacteria like size, volume, density, radius, etc?
Thanks for the help,
Jose —The preceding unsigned comment was added by Josegc (talk • contribs) 00:17, 11 February 2007 (UTC)
thread_title:  Bacteria properties 

message: So then my question is...what causes you to get this virus?  I have a peritoneal catheter in my abdomen and just this last ten or so months (out of six years) have I been getting this bug over and over again at my exit site.  Could it be caused by exposed mould growing in a bathroom?  Where would I find proof of this sort of thing?  Thanks muchly...
---204.112.157.98 18:14, 29 June 2007 (UTC)
replies: text: Well, Staphylococcus aureus isn't a virus (or a mould for that matter), but rather a species of bacteria. S. aureus is, however, an extremely common environmental pathogen and frequently associated with indwelling medical devices (catheters, prosthetic valves, artificial joints, etc). A significant fraction of individuals are S. aureus carriers (up to a third, in some studies), and thus one of your friends/family members/health care providers (or even you) may have been the source of the infection. Since Wikipedia can't give direct medical advice, I suggest you continue to work with your doctor concerning specific treatment options. -- MarcoTolo 00:29, 30 June 2007 (UTC)
thread_title: Question

message: Can I transmit MRSA through sexual contact of any kind?  I was told by a Doctor at University of Louisville Hospital that I could not, but now I am reading studies that say yes...74.130.186.241 (talk) 00:22, 13 August 2010 (UTC)
thread_title:  Remove/Move a line: 

message: Also, look for whiteheaded pimple like lumps where you shave or near any sores. this is a sign of staph. see a dermtologist if you think you have it- i am currently suffering from a particuarly violent strand.  —Preceding unsigned comment added by Wiltingflower (talk • contribs) 12:06, 26 September 2007 (UTC)
thread_title:  Remove/Move a line: 

message: I don't feel qualified to modify the article, but there is some new research that should be included regarding treatment of the bacteria. Some researchers have show that anti-cholesterol medicine can be used against it.
It is described here: New Strategy Cracks Staph Bacterium's "Golden Armor," Making It Vulnerable To Treatment
The abstract of the paper in Science can be found here: A Cholesterol Biosynthesis Inhibitor Blocks Staphylococcus aureus Virulence  —Preceding unsigned comment added by Kristjan Wager (talk • contribs) 07:28, 17 February 2008 (UTC)
thread_title:  New relevant research 

message: Is the citation of this article footnoted #9?  If so, it ought to be after the first sentence of text.  As it is now, the text only appears to have a citation for the last line.  —Preceding unsigned comment added by 71.204.15.239 (talk) 19:25, 24 April 2008 (UTC)
thread_title:  Role of pigment in virulence 

message: I'm currently doing a re-write of what is essentially a total mess (I have not uploaded it yet, though). I will be organising it into sub-sections on antibiotic class. As such, since an awful lot of what is currently in that section is either irrelevant or simply reiterating what has already been said, there will be substantial pruning. Help would be greatly appreciated, especially in the form of content, since I have currently only covered beta-lactams and glycopeptides (the classes I know most about myself). Synthetase (talk) 10:04, 18 June 2008 (UTC)
thread_title: Mechanisms of Antibiotic Resistance

message: I would have thought that S.aureus is the most representative member of the skin flora. I'm deleting it because it's on the very first paragraph and I have a strong feeling that this is inaccurate. Somebody who knows better, please do the needful.
This article sucks very bad. Nothing is mentioned of the role of s.aureus as skin flora and reeks of someone's OCD induced regurgitation.
Rabidphage (talk) 00:27, 28 August 2008 (UTC)
replies: text: I have restored the statistic because it is correct, although I went with the 20% figure since that's what's stated in the reference. Another member of Staphylococcus, S. epidermidis, is probably a more representative member of the skin flora. NighthawkJ (talk) 22:34, 28 August 2008 (UTC)
thread_title: 20-30 % are "staph carriers"?

message: Under the section Role in disease, it points to Staphylococcal infection as further information. However, the section Coagulase-positive points back to Staphylococcus aureus as further information. It may be possible to merge the two sections together, or to expand on them. --ZhongHan  (Email) 06:46, 9 May 2010 (UTC)
thread_title:  Further information on [[Staphylococcus aureus#Role in disease|Role in disease]] loops back 

message: The infobox had a 50,000x SEM of freeze dried Staph, which was hard to interpret, and consisted of a lot of fracture/crack lines that were artifact, and had nothing to do with the organism. Not much else was shown. Commons has far superior false-color SEMs at 20,000 x and 50,000 x showing the typical clustering, and I think the 20,000 x looks better for this (and best coincides with the Gram stain view through the light microscope). The higher mag shows no more detail on individual cells, and shows less info at the next scale up. So I just went ahead and replaced the bad freeze-dry image. Did I miss something? SBHarris 18:34, 20 October 2010 (UTC)
thread_title:  Unfortunate EM replaced 

message: I recently sent my sons stool in for a sample for other tests... it came back that he had staphylocossus aureus. My son is not even 2 yrs old yet he has had
none of the symptoms other than the common cold.. im just wondering how it was contracted.. Their also tellin me theirs no treatment in kids ( only in adults) so they put him on zyrtec for the common cold... Please i need some input here im clue-less Hopefully someone has had a similiar case and can help me understand this a little bit better... even tho i dont wish it on no one even though i dont know how serious it is.. but for a 2 year old surely their gotta be something we can do or symptoms to look for....  — Preceding unsigned comment added by 71.28.220.251 (talk) 21:31, 26 October 2012 (UTC)
replies: text: Why did they culture your son's stool if he only had common cold symptoms?? You should be asking these questions of your doctor, not us. S. aureus in the stool (as a main growth) is only a concern for people with severe diarrhea who might have pseudomembranous entercolitis. Click HERE.SBHarris 22:45, 26 October 2012 (UTC)
thread_title:  My son 

message: Someone changed the order and class of this bacterium. I checked here  and it was correct before (i.e. Bacilli; Bacillales). Reverted. Lesion (talk) 13:46, 15 March 2014 (UTC)
thread_title: Scientific classification

message: There has been a lot of discussion about the role of antibiotics in the healthcare world, and the overuse of them as a "one solution for all." Although it might be easy to critique other's usage of antibiotics, I like to propose this hypothetical situation. If you had a new born child that had a minor bacterial infection, and knew that antibiotics would easily relieve symptoms, would you opt to give your child antibiotics and add to the rapidly growing "overuse" of antibiotics or would you risk withholding them from your child attempting to slow down MRSA mutation?
Thoughts on these sources:
 Ali Grema, H; aHmed Geidam, Y (2015). "Methicillin Resistant Staphylococcus aureus: A Review Article". Journal of Advances in Animal and Veterinary Sciences. 1: 2309–2331. doi:10.14737/journal.aavs/2015/3.2.79.98ISSN.
 Davis, Julian; Davis, Dorothy (2010). "Origins and Evolution of Antibiotic Resistance". American Association of Microbiology. 74: 417–433. doi:10.1128/MMBR.00016-10.
Wang, Xing; Li, Xia; Liu, Wei; Huang, Weichun; Fu, Qihua; Li, Min (2016-01-01). "Molecular Characteristic and Virulence Gene Profiles of Community-Associated Methicillin-Resistant Staphylococcus aureus Isolates from Pediatric Patients in Shanghai, China". Infectious Diseases: 1818. doi:10.3389/fmicb.2016.01818.   — Preceding unsigned comment added by Ncloekman (talk • contribs) 22:16, 27 January 2017 (UTC)
thread_title:  Methicillin Resistant Staphylococcus aureus 

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thread_title:  External links modified 

message: Hi,
This is an excellent article and I thank those who continue to contribute their expertise to improve the content. 
At the moment the treatment section only covers penicillin based treatments and a mention of the triple antibiotic ointment for skin lesions. I believe there’s a need and important place to include treatment for patients where penicillin & cephalosporins are contraindicated, such as Clindamycin ( or perhaps doxycycline (not sure on that one yet).
Any feedback or assistance would be greatly appreciated.
Cheers,
Dr.khatmando (talk) 07:19, 16 July 2018 (UTC)
thread_title:  Treatment section: for patients where penicillin & cephalosporins are contraindicated  

message: Its really hard to find something about this type of resistance. This article says its a resistance common under G+ cocci, while this article only talks about it referring to Staphylococci. Where should the redirect go to? And if you are able to write a paragraph about it in the article I would be really thankfull :) --2A01:112F:742:C00:50C3:4B5A:1321:DB91 (talk) 21:31, 22 January 2019 (UTC)
thread_title:  MLS<sub>B</sub> 

message: English does not mean its America- specific, this p rticle is about a bacterium that is ubiquitous.
The WP style manual explicitly states: USE SI UNITS, other only in artcles about things specific to the USA or England. 
WP isnt Ameripedia. So when I fully cured my food poisoning and nobody fixed it, I'll change this to have the english page of Staphylococcus aureus 
comply with the Manual of style, unless there is a good reason wby it should be ignored?
edit:
to be precise a SI derived unit. I don't think you'll find any papers from American scholars who use°F for anything related to microbiology. 
also again, the US is the only place using that system, so its also complicating the reading for the rest of the english speaking world. 
188.97.91.19 (talk) 18:27, 1 September 2019 (UTC)
replies: text: Thanks for highlighting that -  — soupvector (talk) 19:11, 1 September 2019 (UTC)
thread_title:  why does the Page use °F instead of following WPs manual of style?  

message: In the main article it says: Greek σταφυλόκοκκος, "grape-cluster berry".
That implies that "grape-cluster" translates as "σταφυλο-" and "berry" translates as "κόκκος". This is incorrect. In ancient Greek (where the term comes from) the feminine noun "σταφυλή" (sta-phy-LEE) translates as -simply- "grape" and the masculine noun "κόκκος" (CO-ccus) translates as "granule".
Therefore staphylococcus literally means "grape-granules". E.g. the bacteria when seen under a microscope appear as granules clustered together like grapes. However "grape-cluster" is a redundancy in itself because in the Greek language grapes -by definition- are expected to be clustered together.
Not a big deal, but I thought I'd mention the difference, in case you want to improve the article. Thank you! [XwpisONOMA(at)gMail(dot)com]  — Preceding unsigned comment added by Xwpis ONOMA (talk • contribs) 22:24, 13 December 2019 (UTC)
replies: text: Hi Xwpis ONOMA do you have some sort of source for this? I can add if you have some source. I do not speak Greek so I can not really verify it myself.Garnhami (talk) 22:33, 13 December 2019 (UTC)
thread_title:  Greek translation 

message: I’m concerned about being around other people can I give them this I’m actually quite upset about getting it from surgery 2601:183:C800:7C60:5116:E0D4:FD81:36F7 (talk) 19:48, 24 June 2022 (UTC)
thread_title:  Contagious? From one person to another?