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<|startoftext|><L>CN(CC(=O)Nc1cccc(F)c1)C(=O)[C<mask_1:4>C=CCC1<mask_1:4>
6
29
4
@@H]1C
4
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@H]1C=CCC1
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
@H]1
<|startoftext|><L>CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H<mask_1:6>CCC1<mask_1:6>
5
32
6
]1CC=
6
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H](N)C1CCC1
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
](N)C1
<|startoftext|><L>CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CC<mask_1:3>C1<mask_1:3>
0
39
3
3
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC=CC1
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
C=C
<|startoftext|><L>CN(CC(=O)Nc1cccc(F)c1)C(=<mask_1:6>@H]1CC=CCC1<mask_1:6>
5
25
6
O)[C@
6
CN(CC(=O)Nc1cccc(F)c1)C(=O)CC[C@H]1CC=CCC1
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
O)CC[C
<|startoftext|><L>CN(CC(=O)Nc1cccc(<mask_1:3>F)c1)C(=O)[C@@H]1CC=CCC1<mask_1:3>
0
17
3
3
CN(CC(=O)Nc1cccc(OCCF)c1)C(=O)[C@@H]1CC=CCC1
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
OCC
<|startoftext|><L>CN(CC(=O)Nc1cccc(F)c1)<mask_1:4>O)[C@@H]1CC=CCC1<mask_1:4>
3
22
4
C(=
4
CN(CC(=O)Nc1cccc(F)c1)CC(=O)[C@@H]1CC=CCC1
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
CC(=
<|startoftext|><L>CN(CC(=O)Nc1cccc(F)c1)C(=O)<mask_1:4>1CC=CCC1<mask_1:4>
6
27
4
[C@@H]
4
CN(CC(=O)Nc1cccc(F)c1)C(=O)CCCN1CC=CCC1
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
CCCN
<|startoftext|><L>CN(CC(=O)<mask_1:5>1cccc(F)c1)C(=O)[C@@H]1CC=CCC1<mask_1:5>
2
9
5
Nc
5
CN(CC(=O)NCCCc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
NCCCc
<|startoftext|><L>CN(CC(=O)Nc1cccc(F)<mask_1:3>=O)[C@@H]1CC=CCC1<mask_1:3>
5
19
3
c1)C(
3
CN(CC(=O)Nc1cccc(F)c1C=O)[C@@H]1CC=CCC1
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
c1C
<|startoftext|><L>C<mask_1:2>C(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1<mask_1:2>
3
1
2
N(C
2
CN(C(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
CN(CC(=O)Nc1cccc(F)c1)C(=O)[C@@H]1CC=CCC1
N(
<|startoftext|><L>Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3cc<mask_1:11>)C(=O)[C@H]2[C@H]2CCCN21<mask_1:11>
10
44
11
c4ccccc4c3
11
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3C)C(=O)[C@H]2[C@H]2CCCN21
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
c4ccccc4c3C
<|startoftext|><L>Cc1ccc2c<mask_1:8>)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21<mask_1:8>
4
8
8
(c1C
8
Cc1ccc2c(c1)C(=O)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
(c1)C(=O
<|startoftext|><L>Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(<mask_1:6>O)[C@H]2[C@H]2CCCN21<mask_1:6>
1
57
6
=
6
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)C(=O)[C@H]2[C@H]2CCCN21
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
=O)C(=
<|startoftext|><L>Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]<mask_1:4>CCN21<mask_1:4>
8
65
4
2[C@H]2C
4
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2N2CCCN21
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
2N2C
<|startoftext|><L>Cc1ccc2c(c1C)NC(=O)<mask_1:4>21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21<mask_1:4>
5
19
4
[C@@]
4
Cc1ccc2c(c1C)NC(=O)[C@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
[C@]
<|startoftext|><L>Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H<mask_1:5>C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21<mask_1:5>
2
31
5
]2
5
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C=CC(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
]2C=C
<|startoftext|><L>Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3<mask_1:1>[C@H]2[C@H]2CCCN21<mask_1:1>
6
54
1
)C(=O)
1
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)[C@H]2[C@H]2CCCN21
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
)
<|startoftext|><L>Cc1ccc2c(c1C)NC(=<mask_1:4>]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21<mask_1:4>
6
17
4
O)[C@@
4
Cc1ccc2c(c1C)NC(=O)[C]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
O)[C
<|startoftext|><L>Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=<mask_1:1>c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21<mask_1:1>
4
36
1
O)N(
1
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=Nc3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
N
<|startoftext|><L>Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c<mask_1:5>]2[C@H]2CCCN21<mask_1:5>
11
53
5
3)C(=O)[C@H
5
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)[C@]2[C@H]2CCCN21
Cc1ccc2c(c1C)NC(=O)[C@@]21[C@@H]2C(=O)N(c3ccc4ccccc4c3)C(=O)[C@H]2[C@H]2CCCN21
3)[C@
<|startoftext|><L>CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=<mask_1:3>NC(=O)NC3=O)cc2Cl)cc1<mask_1:3>
2
33
3
O)
3
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NNC(=O)NC3=O)cc2Cl)cc1
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
O)N
<|startoftext|><L>CC(C)(C)c1ccc(C(=O)<mask_1:6>c(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1<mask_1:6>
5
19
6
Oc2cc
6
CC(C)(C)c1ccc(C(=O)COc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
COc2cc
<|startoftext|><L>CC(C)(C)c1ccc(C(=O<mask_1:3>ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1<mask_1:3>
4
18
3
)Oc2
3
CC(C)(C)c1ccc(C(=O)c2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
)c2
<|startoftext|><L>CC(C)(C)<mask_1:3>1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1<mask_1:3>
1
8
3
c
3
CC(C)(C)COc1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
COc
<|startoftext|><L>CC(C)(C)c1<mask_1:8>=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1<mask_1:8>
6
10
8
ccc(C(
8
CC(C)(C)c1ccc(OCC(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
ccc(OCC(
<|startoftext|><L>CC(C)(<mask_1:7>C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1<mask_1:7>
8
6
7
C)c1ccc(
8
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
C)c1ccc(
<|startoftext|><L>CC(C)<mask_1:7>C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1<mask_1:7>
1
5
7
(
7
CC(C)[C@@H](C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
[C@@H](
<|startoftext|><L>CC(C)(C)c1cc<mask_1:6>c2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1<mask_1:6>
8
12
6
c(C(=O)O
6
CC(C)(C)c1ccc(OCCOc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
c(OCCO
<|startoftext|><L>CC(C)(C)c1ccc(C(=O)Oc2ccc(C<mask_1:5>)NC(=O)NC3=O)cc2Cl)cc1<mask_1:5>
7
27
5
=C3C(=O
5
CC(C)(C)c1ccc(C(=O)Oc2ccc(C3=C(C)NC(=O)NC3=O)cc2Cl)cc1
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
3=C(C
<|startoftext|><L>CC(C)<mask_1:5>c(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1<mask_1:5>
7
5
5
(C)c1cc
5
CC(C)Oc1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
CC(C)(C)c1ccc(C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl)cc1
Oc1cc
<|startoftext|><L>COC(=O)c1cc(<mask_1:7>(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1<mask_1:7>
5
12
7
OC)cc
7
COC(=O)c1cc(C)c(C)c(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
C)c(C)c
<|startoftext|><L>COC(=O)c1cc(OC)cc(C(=O)<mask_1:4>2CCCC[C@H]2CCNC(C)=O)c1<mask_1:4>
1
23
4
N
4
COC(=O)c1cc(OC)cc(C(=O)NCCN2CCCC[C@H]2CCNC(C)=O)c1
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
NCCN
<|startoftext|><L>COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCN<mask_1:5>(C)=O)c1<mask_1:5>
1
38
5
C
5
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNS(C)C(C)=O)c1
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
S(C)C
<|startoftext|><L>COC(=O<mask_1:7>(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1<mask_1:7>
5
6
7
)c1cc
7
COC(=O)COc1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
)COc1cc
<|startoftext|><L>COC(=O)c1cc(OC)cc(C(<mask_1:5>N2CCCC[C@H]2CCNC(C)=O)c1<mask_1:5>
3
20
5
=O)
5
COC(=O)c1cc(OC)cc(C(=O)NCN2CCCC[C@H]2CCNC(C)=O)c1
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
=O)NC
<|startoftext|><L>COC(=O)c1c<mask_1:7>OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1<mask_1:7>
2
10
7
c(
7
COC(=O)c1cc(C(=O)OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
c(C(=O)
<|startoftext|><L>COC(=<mask_1:7>c(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1<mask_1:7>
5
5
7
O)c1c
7
COC(=O)COc1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
O)COc1c
<|startoftext|><L>COC(=O)c1cc(OC)cc(<mask_1:6>O)N2CCCC[C@H]2CCNC(C)=O)c1<mask_1:6>
3
18
6
C(=
6
COC(=O)c1cc(OC)cc(S(=O)(O)N2CCCC[C@H]2CCNC(C)=O)c1
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
S(=O)(
<|startoftext|><L>COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2C<mask_1:4>NC(C)=O)c1<mask_1:4>
1
36
4
C
4
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2C(=O)NC(C)=O)c1
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
(=O)
<|startoftext|><L>COC(=O)c1cc(OC)cc(C(=O)N2CCC<mask_1:5>CCNC(C)=O)c1<mask_1:5>
7
28
5
C[C@H]2
5
COC(=O)c1cc(OC)cc(C(=O)N2CCCCCCC2CCNC(C)=O)c1
COC(=O)c1cc(OC)cc(C(=O)N2CCCC[C@H]2CCNC(C)=O)c1
CCCC2
<|startoftext|><L>Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@<mask_1:5>O)C2)s1<mask_1:5>
3
33
5
H](
5
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](CCO)C2)s1
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
H](CC
<|startoftext|><L>Cc1ccccc1-c1ncc(CN2<mask_1:2>CC[C@H](N)[C@@H](O)C2)s1<mask_1:2>
0
19
2
2
Cc1ccccc1-c1ncc(CN2CCCC[C@H](N)[C@@H](O)C2)s1
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
CC
<|startoftext|><L>Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2<mask_1:6>s1<mask_1:6>
1
40
6
)
6
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)c(=O)s1
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
)c(=O)
<|startoftext|><L>Cc1ccccc<mask_1:2>-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1<mask_1:2>
1
8
2
1
2
Cc1ccccc1C-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
1C
<|startoftext|><L>Cc1ccccc1-c1ncc(CN2CC[C@H](N)<mask_1:2>](O)C2)s1<mask_1:2>
5
29
2
[C@@H
2
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C](O)C2)s1
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
[C
<|startoftext|><L>Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C<mask_1:4>1<mask_1:4>
3
39
4
2)s
4
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)cn1
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
2)cn
<|startoftext|><L>Cc1ccccc1-c1ncc(CN2CC[C@H](<mask_1:6>@H](O)C2)s1<mask_1:6>
5
27
6
N)[C@
6
Cc1ccccc1-c1ncc(CN2CC[C@H](CO)[C@@H](O)C2)s1
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
CO)[C@
<|startoftext|><L>Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@<mask_1:6>O)C2)s1<mask_1:6>
4
32
6
@H](
6
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@H](CCCO)C2)s1
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
H](CCC
<|startoftext|><L>Cc1ccccc1-c1ncc(CN2CC[C@H](<mask_1:6>@H](O)C2)s1<mask_1:6>
5
27
6
N)[C@
6
Cc1ccccc1-c1ncc(CN2CC[C@H](CO)[C@@H](O)C2)s1
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
CO)[C@
<|startoftext|><L>Cc1ccccc<mask_1:4>1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1<mask_1:4>
3
8
4
1-c
4
Cc1ccccc1CCc1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
Cc1ccccc1-c1ncc(CN2CC[C@H](N)[C@@H](O)C2)s1
1CCc
<|startoftext|><L>O=<mask_1:4>Cc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1<mask_1:4>
3
2
4
C(C
4
O=C(NCCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
C(NC
<|startoftext|><L>O=C(CCc1<mask_1:5>O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1<mask_1:5>
4
8
5
ccc(
5
O=C(CCc1ccc(CO)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
ccc(C
<|startoftext|><L>O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O<mask_1:3>)C1<mask_1:3>
0
45
3
3
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](OCCO)C1
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
CCO
<|startoftext|><L>O=C(CCc1c<mask_1:6>O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1<mask_1:6>
3
9
6
cc(
6
O=C(CCc1ccc(OCCO)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
cc(OCC
<|startoftext|><L>O=C(CCc1c<mask_1:3>1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1<mask_1:3>
7
9
3
cc(O)cc
3
O=C(CCc1ccsc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
csc
<|startoftext|><L>O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[<mask_1:6>@H](O)C1<mask_1:6>
1
39
6
C
6
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H][C@H](O)C1
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
C@H][C
<|startoftext|><L>O=C(<mask_1:7>c(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1<mask_1:7>
6
4
7
CCc1cc
7
O=C(CCCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
CCCc1cc
<|startoftext|><L>O<mask_1:7>C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1<mask_1:7>
1
1
7
=
7
O=C(O)CCC(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
=C(O)CC
<|startoftext|><L>O=C(C<mask_1:7>c1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1<mask_1:7>
1
5
7
C
7
O=C(COC(=O)Cc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
OC(=O)C
<|startoftext|><L>O=C(CCc1ccc(O)cc<mask_1:5>N1C[C@@H](Cc2cnccn2)[C@H](O)C1<mask_1:5>
2
16
5
1)
5
O=C(CCc1ccc(O)cc1Cl)NN1C[C@@H](Cc2cnccn2)[C@H](O)C1
O=C(CCc1ccc(O)cc1)N1C[C@@H](Cc2cnccn2)[C@H](O)C1
1Cl)N
<|startoftext|><L>C[C@H](Oc1cccc2c1<mask_1:6>C2=O)C(=O)Nc1ccc(F)c(F)c1<mask_1:6>
2
17
6
CC
6
C[C@H](Oc1cccc2c1CCC(O)C2=O)C(=O)Nc1ccc(F)c(F)c1
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
CCC(O)
<|startoftext|><L>C[C@H](<mask_1:3>Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1<mask_1:3>
0
7
3
3
C[C@H](NCCOc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
NCC
<|startoftext|><L>C[C@H](Oc1cccc2c1CCC2<mask_1:4>C(=O)Nc1ccc(F)c(F)c1<mask_1:4>
3
21
4
=O)
4
C[C@H](Oc1cccc2c1CCC2=O)NC(=O)Nc1ccc(F)c(F)c1
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
=O)N
<|startoftext|><L>C<mask_1:5>H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1<mask_1:5>
3
1
5
[C@
5
CC[C@@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
C[C@@
<|startoftext|><L>C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c<mask_1:6>)c1<mask_1:6>
2
39
6
(F
6
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(C(F)F)c1
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
(C(F)F
<|startoftext|><L>C[C@H](Oc1cccc2c1CC<mask_1:6>=O)C(=O)Nc1ccc(F)c(F)c1<mask_1:6>
2
19
6
C2
6
C[C@H](Oc1cccc2c1CCCC2)C(=O)C(=O)Nc1ccc(F)c(F)c1
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
CC2)C(
<|startoftext|><L>C[C@H](Oc1cccc2c1C<mask_1:1>CC2=O)C(=O)Nc1ccc(F)c(F)c1<mask_1:1>
0
18
1
1
C[C@H](Oc1cccc2c1CCCC2=O)C(=O)Nc1ccc(F)c(F)c1
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
C
<|startoftext|><L>C[C@H](Oc1cccc2c1CCC<mask_1:5>=O)C(=O)Nc1ccc(F)c(F)c1<mask_1:5>
1
20
5
2
5
C[C@H](Oc1cccc2c1CCCC2)C(=O)C(=O)Nc1ccc(F)c(F)c1
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
C2)C(
<|startoftext|><L>C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc<mask_1:5>)c(F)c1<mask_1:5>
6
31
5
1ccc(F
5
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1sc(F)c(F)c1
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
1sc(F
<|startoftext|><L>C[C@<mask_1:2>Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1<mask_1:2>
3
4
2
H](
2
C[C@](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
C[C@H](Oc1cccc2c1CCC2=O)C(=O)Nc1ccc(F)c(F)c1
](
<|startoftext|><L><mask_1:3>c1nc(F)c(F)c(C#Cc2ccccc2)c1F<mask_1:3>
1
0
3
F
3
O=Cc1nc(F)c(F)c(C#Cc2ccccc2)c1F
Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F
O=C
<|startoftext|><L>Fc1nc(F)c(F)c(C#Cc2ccccc<mask_1:2>)c1F<mask_1:2>
1
24
2
2
2
Fc1nc(F)c(F)c(C#Cc2ccccc2F)c1F
Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F
2F
<|startoftext|><L>Fc1nc(F)c(F)c(C#Cc2ccccc2<mask_1:1>)c1F<mask_1:1>
0
25
1
1
Fc1nc(F)c(F)c(C#Cc2ccccc2F)c1F
Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F
F
<|startoftext|><L>Fc1nc(F)c(F)c(C#Cc2ccc<mask_1:3>cc2)c1F<mask_1:3>
0
22
3
3
Fc1nc(F)c(F)c(C#Cc2ccc(F)cc2)c1F
Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F
(F)
<|startoftext|><L>Fc1nc(F)c(F<mask_1:4>C#Cc2ccccc2)c1F<mask_1:4>
3
11
4
)c(
4
Fc1nc(F)c(F)c(NC#Cc2ccccc2)c1F
Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F
)c(N
<|startoftext|><L>Fc1nc(F)c(F)c(C<mask_1:2>Cc2ccccc2)c1F<mask_1:2>
1
15
2
#
2
Fc1nc(F)c(F)c(CNCCc2ccccc2)c1F
Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F
NC
<|startoftext|><L>Fc1nc(F)c(F)c(C#Cc2ccc<mask_1:2>)c1F<mask_1:2>
3
22
2
cc2
2
Fc1nc(F)c(F)c(C#Cc2ccco2)c1F
Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F
o2
<|startoftext|><L>Fc1nc(F)c(F)c(<mask_1:4>Cc2ccccc2)c1F<mask_1:4>
2
14
4
C#
4
Fc1nc(F)c(F)c(N(C)Cc2ccccc2)c1F
Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F
N(C)
<|startoftext|><L>Fc1nc(F)c(<mask_1:2>(C#Cc2ccccc2)c1F<mask_1:2>
3
10
2
F)c
2
Fc1nc(F)c(F)(C#Cc2ccccc2)c1F
Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F
F)
<|startoftext|><L>Fc1nc(F)c(F)c(C#Cc2<mask_1:2>ccccc2)c1F<mask_1:2>
0
19
2
2
Fc1nc(F)c(F)c(C#Cc2ccccccc2)c1F
Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F
cc
<|startoftext|><L>COc1cc(-c2n<mask_1:3>3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F<mask_1:3>
4
11
3
c(CN
3
COc1cc(-c2nc(N3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
c(N
<|startoftext|><L>COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc<mask_1:3>F<mask_1:3>
1
46
3
1
3
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1OCF
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
1OC
<|startoftext|><L>COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)<mask_1:6>C)o2)ccc1F<mask_1:6>
2
36
6
c(
6
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C(C)C)o2)ccc1F
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
c(C(C)
<|startoftext|><L>COc1cc(<mask_1:6>N3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F<mask_1:6>
7
7
6
-c2nc(C
6
COc1cc(-c2nc(N3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
-c2nc(
<|startoftext|><L>COc1cc(-c2nc(CN<mask_1:1>3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F<mask_1:1>
0
15
1
1
COc1cc(-c2nc(CNC3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
C
<|startoftext|><L>COc1cc(-<mask_1:4>nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F<mask_1:4>
2
8
4
c2
4
COc1cc(-c2ncnc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
c2nc
<|startoftext|><L>COc1cc(-c2nc(CN3CCC(Oc4<mask_1:6>c4OC)CC3)c(C)o2)ccc1F<mask_1:6>
4
23
6
cccc
6
COc1cc(-c2nc(CN3CCC(Oc4nc(C)sc4OC)CC3)c(C)o2)ccc1F
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
nc(C)s
<|startoftext|><L><mask_1:3>c(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F<mask_1:3>
5
0
3
COc1c
3
c1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
c1c
<|startoftext|><L>COc1cc(-c2nc(CN3CCC<mask_1:4>Oc4ccccc4OC)CC3)c(C)o2)ccc1F<mask_1:4>
1
19
4
(
4
COc1cc(-c2nc(CN3CCC(O)(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
(O)(
<|startoftext|><L>COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2<mask_1:1>1F<mask_1:1>
4
42
1
)ccc
1
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)1F
COc1cc(-c2nc(CN3CCC(Oc4ccccc4OC)CC3)c(C)o2)ccc1F
)
<|startoftext|><L>COc<mask_1:3>cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21<mask_1:3>
7
3
3
1ccc(F)
3
COc1sccc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
1sc
<|startoftext|><L>COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2<mask_1:2>c3ccccn3)C[C@@H]21<mask_1:2>
3
32
2
CN(
2
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2N(c3ccccn3)C[C@@H]21
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
N(
<|startoftext|><L>COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C<mask_1:2>]21<mask_1:2>
3
47
2
@@H
2
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@H]21
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
@H
<|startoftext|><L>COc1ccc(F)<mask_1:5>c1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21<mask_1:5>
1
10
5
c
5
COc1ccc(F)c(Cl)c1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
c(Cl)
<|startoftext|><L>COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[<mask_1:5>]21<mask_1:5>
4
46
5
C@@H
4
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
C@@H
<|startoftext|><L>CO<mask_1:4>ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21<mask_1:4>
2
2
4
c1
4
COCOc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
COc1
<|startoftext|><L>COc1cc<mask_1:4>c(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21<mask_1:4>
0
6
4
4
COc1cc(Cl)c(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
(Cl)
<|startoftext|><L>COc1ccc(F)cc1S(=O)(=O)N1CC<mask_1:7>CN(c3ccccn3)C[C@@H]21<mask_1:7>
6
26
7
[C@H]2
7
COc1ccc(F)cc1S(=O)(=O)N1CC[C@@H]2CN(c3ccccn3)C[C@@H]21
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
[C@@H]2
<|startoftext|><L>COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]<mask_1:5>CN(c3ccccn3)C[C@@H]21<mask_1:5>
1
31
5
2
5
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2OCCCCN(c3ccccn3)C[C@@H]21
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
2OCCC
<|startoftext|><L>COc1ccc(F)cc1S(=O)(=O)N<mask_1:4>CC[C@H]2CN(c3ccccn3)C[C@@H]21<mask_1:4>
1
23
4
1
4
COc1ccc(F)cc1S(=O)(=O)N1CCNCC[C@H]2CN(c3ccccn3)C[C@@H]21
COc1ccc(F)cc1S(=O)(=O)N1CC[C@H]2CN(c3ccccn3)C[C@@H]21
1CCN