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<|startoftext|><L>CCOC(=O)c1cc<mask_1:5>=O)OCC)c(=O)[nH]c1NN<mask_1:5> | 3 | 12 | 5 | (C( | 5 | CCOC(=O)c1cc(OCC(=O)OCC)c(=O)[nH]c1NN | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NN | (OCC( |
<|startoftext|><L>CCOC(=O)c1cc(C(=O)<mask_1:1>C)c(=O)[nH]c1NN<mask_1:1> | 2 | 18 | 1 | OC | 1 | CCOC(=O)c1cc(C(=O)OC)c(=O)[nH]c1NN | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NN | O |
<|startoftext|><L>CCOC(=O)c1cc(C(<mask_1:2>CC)c(=O)[nH]c1NN<mask_1:2> | 4 | 15 | 2 | =O)O | 2 | CCOC(=O)c1cc(C(C)CC)c(=O)[nH]c1NN | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NN | C) |
<|startoftext|><L>CCOC(=O)c1cc(C<mask_1:4>)OCC)c(=O)[nH]c1NN<mask_1:4> | 3 | 14 | 4 | (=O | 4 | CCOC(=O)c1cc(CC(=O)OCC)c(=O)[nH]c1NN | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NN | C(=O |
<|startoftext|><L>CCOC(=O)c1cc(<mask_1:3>=O)OCC)c(=O)[nH]c1NN<mask_1:3> | 2 | 13 | 3 | C( | 3 | CCOC(=O)c1cc(NC(=O)OCC)c(=O)[nH]c1NN | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NN | NC( |
<|startoftext|><L>CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH<mask_1:3>N<mask_1:3> | 4 | 30 | 3 | ]c1N | 3 | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1N | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NN | ]c1 |
<|startoftext|><L>CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1N<mask_1:3>N<mask_1:3> | 0 | 34 | 3 | 3 | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NCC#N | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NN | CC# |
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<|startoftext|><L>CCOC(=O)c1cc(C<mask_1:1>(=O)OCC)c(=O)[nH]c1NN<mask_1:1> | 0 | 14 | 1 | 1 | CCOC(=O)c1cc(CC(=O)OCC)c(=O)[nH]c1NN | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NN | C |
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<|startoftext|><L>CCOC(=O)c1<mask_1:5>c(C(=O)OCC)c(=O)[nH]c1NN<mask_1:5> | 1 | 10 | 5 | c | 5 | CCOC(=O)c1c(Br)c(C(=O)OCC)c(=O)[nH]c1NN | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NN | c(Br) |
<|startoftext|><L>CCOC(=O)c1cc(C(=O)<mask_1:5>C)c(=O)[nH]c1NN<mask_1:5> | 2 | 18 | 5 | OC | 5 | CCOC(=O)c1cc(C(=O)OC(C)C)c(=O)[nH]c1NN | CCOC(=O)c1cc(C(=O)OCC)c(=O)[nH]c1NN | OC(C) |
<|startoftext|><L>Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(<mask_1:1>C)Cc3ccco3)CCO2)n1<mask_1:1> | 0 | 35 | 1 | 1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(CC)Cc3ccco3)CCO2)n1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | C |
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<|startoftext|><L>Cc1n[nH]c(<mask_1:5>CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1<mask_1:5> | 7 | 10 | 5 | [C@@H]2 | 5 | Cc1n[nH]c([C]2CCN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | [C]2C |
<|startoftext|><L>Cc1n[nH]c([C@@H]2CN<mask_1:5>[C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1<mask_1:5> | 1 | 19 | 5 | ( | 5 | Cc1n[nH]c([C@@H]2CN(CCCN[C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | (CCCN |
<|startoftext|><L>Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O<mask_1:4>3ccco3)CCO2)n1<mask_1:4> | 7 | 32 | 4 | )N(C)Cc | 4 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)NCc3ccco3)CCO2)n1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | )NCc |
<|startoftext|><L>Cc1n[nH]c([C@@H<mask_1:5>CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1<mask_1:5> | 2 | 15 | 5 | ]2 | 5 | Cc1n[nH]c([C@@H]2CCCCN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | ]2CCC |
<|startoftext|><L>Cc1n[nH]<mask_1:5>@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1<mask_1:5> | 4 | 8 | 5 | c([C | 5 | Cc1n[nH]c(C[C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | c(C[C |
<|startoftext|><L>Cc1n[nH]c([C@@H]<mask_1:6>([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1<mask_1:6> | 3 | 16 | 6 | 2CN | 6 | Cc1n[nH]c([C@@H]2[C@H]([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | 2[C@H] |
<|startoftext|><L>Cc1n[nH]c([C@@H]2CN([C<mask_1:2>C(=O)N(C)Cc3ccco3)CCO2)n1<mask_1:2> | 6 | 22 | 2 | @H](C) | 2 | Cc1n[nH]c([C@@H]2CN([CH]C(=O)N(C)Cc3ccco3)CCO2)n1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | H] |
<|startoftext|><L>Cc1n[nH]c([<mask_1:5>]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1<mask_1:5> | 4 | 11 | 5 | C@@H | 4 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | C@@H |
<|startoftext|><L>Cc1n[nH]c([C@<mask_1:6>]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1<mask_1:6> | 2 | 13 | 6 | @H | 6 | Cc1n[nH]c([C@H][C@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | Cc1n[nH]c([C@@H]2CN([C@H](C)C(=O)N(C)Cc3ccco3)CCO2)n1 | H][C@H |
<|startoftext|><L>Cc1ccc([C@H]<mask_1:7>(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1<mask_1:7> | 3 | 12 | 7 | 2CN | 7 | Cc1ccc([C@H]2C[C@H](C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | 2C[C@H] |
<|startoftext|><L>Cc1ccc([C@H]2CN(C(=O)c3ccnc(<mask_1:4>C)(C)C)c3)CCO2)o1<mask_1:4> | 3 | 28 | 4 | OC( | 4 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(NCC(C)(C)C)c3)CCO2)o1 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | NCC( |
<|startoftext|><L>Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(<mask_1:4>C)C)c3)CCO2)o1<mask_1:4> | 0 | 34 | 4 | 4 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C(C)C)c3)CCO2)o1 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | C)C( |
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<|startoftext|><L>Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(<mask_1:3>C)c3)CCO2)o1<mask_1:3> | 5 | 31 | 3 | C)(C) | 3 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)CC)c3)CCO2)o1 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | C)C |
<|startoftext|><L>Cc1ccc([C@H]2CN(<mask_1:1>3ccnc(OC(C)(C)C)c3)CCO2)o1<mask_1:1> | 6 | 16 | 1 | C(=O)c | 1 | Cc1ccc([C@H]2CN(c3ccnc(OC(C)(C)C)c3)CCO2)o1 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | c |
<|startoftext|><L>Cc1ccc([C@H]2CN(C(<mask_1:6>)c3ccnc(OC(C)(C)C)c3)CCO2)o1<mask_1:6> | 2 | 18 | 6 | =O | 6 | Cc1ccc([C@H]2CN(C(=O)N(C)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | =O)N(C |
<|startoftext|><L>Cc1ccc([C@H]2<mask_1:7>O)c3ccnc(OC(C)(C)C)c3)CCO2)o1<mask_1:7> | 6 | 13 | 7 | CN(C(= | 7 | Cc1ccc([C@H]2CN(CC(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | CN(CC(= |
<|startoftext|><L>Cc<mask_1:6>([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1<mask_1:6> | 4 | 2 | 6 | 1ccc | 6 | Cc1nc(C)([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | 1nc(C) |
<|startoftext|><L>Cc1ccc([C@H]2CN(C(=O)c3c<mask_1:2>(OC(C)(C)C)c3)CCO2)o1<mask_1:2> | 3 | 24 | 2 | cnc | 2 | Cc1ccc([C@H]2CN(C(=O)c3cnn(OC(C)(C)C)c3)CCO2)o1 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | nn |
<|startoftext|><L>Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)<mask_1:6>1<mask_1:6> | 1 | 46 | 6 | o | 6 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)c(Cl)c1 | Cc1ccc([C@H]2CN(C(=O)c3ccnc(OC(C)(C)C)c3)CCO2)o1 | c(Cl)c |
<|startoftext|><L>Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C<mask_1:5>)c5ccccc5C4=O)nc3c12<mask_1:5> | 3 | 35 | 5 | (=O | 5 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(C)(C)c5ccccc5C4=O)nc3c12 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | (C)(C |
<|startoftext|><L>Cc1<mask_1:3>(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12<mask_1:3> | 1 | 3 | 3 | c | 3 | Cc1ccc(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | ccc |
<|startoftext|><L>Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C<mask_1:2>c5ccccc5C4=O)nc3c12<mask_1:2> | 4 | 35 | 2 | (=O) | 2 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4CCCc5ccccc5C4=O)nc3c12 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | CC |
<|startoftext|><L>Cc1c(C<mask_1:4>N2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12<mask_1:4> | 6 | 6 | 4 | )n(CCC | 4 | Cc1c(C(=O)N2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | (=O) |
<|startoftext|><L>Cc1c(C)n(CCCN<mask_1:3>)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12<mask_1:3> | 7 | 13 | 3 | 2CCOCC2 | 3 | Cc1c(C)n(CCCN(C))c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | (C) |
<|startoftext|><L>Cc1c(C)n(CCC<mask_1:6>2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12<mask_1:6> | 7 | 12 | 6 | N2CCOCC | 6 | Cc1c(C)n(CCCn2ccnc2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | n2ccnc |
<|startoftext|><L>Cc1c(C<mask_1:4>CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12<mask_1:4> | 8 | 6 | 4 | )n(CCCN2 | 4 | Cc1c(C2(C)CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | 2(C) |
<|startoftext|><L>Cc1c(C)n<mask_1:3>N2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12<mask_1:3> | 4 | 8 | 3 | (CCC | 3 | Cc1c(C)n(CCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | (CC |
<|startoftext|><L>Cc1c(C)<mask_1:6>COCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12<mask_1:6> | 8 | 7 | 6 | n(CCCN2C | 6 | Cc1c(C)n(CN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | n(CN2C |
<|startoftext|><L>Cc1c(C)n(CCCN2CCOCC2)c2ncn3n<mask_1:8>C(=O)c5ccccc5C4=O)nc3c12<mask_1:8> | 6 | 28 | 8 | c(CCN4 | 8 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C/C(=O)c5ccccc5C4=O)nc3c12 | Cc1c(C)n(CCCN2CCOCC2)c2ncn3nc(CCN4C(=O)c5ccccc5C4=O)nc3c12 | c(CCN4C/ |
<|startoftext|><L>COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(<mask_1:8>C)[C@@H]2c2cccnc2)c(O)c1<mask_1:8> | 2 | 31 | 8 | C) | 8 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C](C)[C@@H]2c2cccnc2)c(O)c1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | C)C)[C]( |
<|startoftext|><L>COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(<mask_1:3>C)[C@@H]2c2cccnc2)c(O)c1<mask_1:3> | 2 | 31 | 3 | C) | 3 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)CC)[C@@H]2c2cccnc2)c(O)c1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | C)C |
<|startoftext|><L>COc<mask_1:1>c(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1<mask_1:1> | 3 | 3 | 1 | 1cc | 1 | COc1c(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | 1 |
<|startoftext|><L>COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc<mask_1:3>)c(O)c1<mask_1:3> | 1 | 49 | 3 | 2 | 3 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2Cl)c(O)c1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | 2Cl |
<|startoftext|><L>COc1ccc(C(<mask_1:1>)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1<mask_1:1> | 2 | 10 | 1 | =O | 1 | COc1ccc(C(C)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | C |
<|startoftext|><L>COc1ccc(C(=O)C2=C(O)C(=O)N<mask_1:1>N(C)C)[C@@H]2c2cccnc2)c(O)c1<mask_1:1> | 3 | 26 | 1 | (CC | 1 | COc1ccc(C(=O)C2=C(O)C(=O)N(N(C)C)[C@@H]2c2cccnc2)c(O)c1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | ( |
<|startoftext|><L>COc1ccc(C(=O)C2=C(O)C(=O)N(CC<mask_1:1>[C@@H]2c2cccnc2)c(O)c1<mask_1:1> | 6 | 29 | 1 | N(C)C) | 1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CC)[C@@H]2c2cccnc2)c(O)c1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | ) |
<|startoftext|><L>COc1ccc(C(=O)<mask_1:4>C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1<mask_1:4> | 7 | 13 | 4 | C2=C(O) | 4 | COc1ccc(C(=O)C2=CC(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | C2=C |
<|startoftext|><L>COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c<mask_1:2>O)c1<mask_1:2> | 1 | 52 | 2 | ( | 2 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(CO)c1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | (C |
<|startoftext|><L>COc1ccc(C(<mask_1:7>C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1<mask_1:7> | 6 | 10 | 7 | =O)C2= | 7 | COc1ccc(C(=O)C2=CC(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | COc1ccc(C(=O)C2=C(O)C(=O)N(CCN(C)C)[C@@H]2c2cccnc2)c(O)c1 | =O)C2=C |
<|startoftext|><L>O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]<mask_1:3>CCCC2<mask_1:3> | 5 | 35 | 3 | c1=O) | 3 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]1)CCCCC2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | 1)C |
<|startoftext|><L>O=C(NCCS(=O)(=O)<mask_1:6>1CCCC1)c1cc2c([nH]c1=O)CCCC2<mask_1:6> | 1 | 16 | 6 | N | 6 | O=C(NCCS(=O)(=O)N[C@H]1CCCC1)c1cc2c([nH]c1=O)CCCC2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | N[C@H] |
<|startoftext|><L>O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CC<mask_1:2>C2<mask_1:2> | 1 | 42 | 2 | C | 2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCCC2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | CC |
<|startoftext|><L>O=C(NCCS(=O)(=O)<mask_1:5>CCCC1)c1cc2c([nH]c1=O)CCCC2<mask_1:5> | 2 | 16 | 5 | N1 | 5 | O=C(NCCS(=O)(=O)N1CCCCCCC1)c1cc2c([nH]c1=O)CCCC2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | N1CCC |
<|startoftext|><L>O=C<mask_1:6>CS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2<mask_1:6> | 3 | 3 | 6 | (NC | 6 | O=C(NCCCCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | (NCCCC |
<|startoftext|><L>O=C(N<mask_1:6>=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2<mask_1:6> | 4 | 5 | 6 | CCS( | 6 | O=C(NCCCNS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | CCCNS( |
<|startoftext|><L>O=C(NCCS(=O)(=O)N1CC<mask_1:2>c1cc2c([nH]c1=O)CCCC2<mask_1:2> | 4 | 20 | 2 | CC1) | 2 | O=C(NCCS(=O)(=O)N1CC1)c1cc2c([nH]c1=O)CCCC2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | 1) |
<|startoftext|><L>O=C(NC<mask_1:4>)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2<mask_1:4> | 5 | 6 | 4 | CS(=O | 4 | O=C(NCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | S(=O |
<|startoftext|><L>O=C(NCCS(=<mask_1:3>O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2<mask_1:3> | 4 | 10 | 3 | O)(= | 4 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | O)(= |
<|startoftext|><L>O<mask_1:5>C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2<mask_1:5> | 1 | 1 | 5 | = | 5 | O=C(O)C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | O=C(NCCS(=O)(=O)N1CCCC1)c1cc2c([nH]c1=O)CCCC2 | =C(O) |
<|startoftext|><L>O=C(O)c1cccc(CN2CCN3<mask_1:3>cccc2c43)c1<mask_1:3> | 5 | 20 | 3 | CCOc4 | 3 | O=C(O)c1cccc(CN2CCN3Cc4cccc2c43)c1 | O=C(O)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | Cc4 |
<|startoftext|><L>O=C(<mask_1:2>O)c1cccc(CN2CCN3CCOc4cccc2c43)c1<mask_1:2> | 0 | 4 | 2 | 2 | O=C(CCO)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | O=C(O)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | CC |
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<|startoftext|><L>O=C(O)<mask_1:3>cccc(CN2CCN3CCOc4cccc2c43)c1<mask_1:3> | 2 | 6 | 3 | c1 | 3 | O=C(O)Cc1cccc(CN2CCN3CCOc4cccc2c43)c1 | O=C(O)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | Cc1 |
<|startoftext|><L>O=C(O)c1cccc(<mask_1:5>2CCN3CCOc4cccc2c43)c1<mask_1:5> | 2 | 13 | 5 | CN | 5 | O=C(O)c1cccc(OCCCN2CCN3CCOc4cccc2c43)c1 | O=C(O)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | OCCCN |
<|startoftext|><L>O=C(O)c1cccc(CN<mask_1:1>2CCN3CCOc4cccc2c43)c1<mask_1:1> | 0 | 15 | 1 | 1 | O=C(O)c1cccc(CNC2CCN3CCOc4cccc2c43)c1 | O=C(O)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | C |
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<|startoftext|><L>O=C(O)c1cccc(<mask_1:4>N3CCOc4cccc2c43)c1<mask_1:4> | 5 | 13 | 4 | CN2CC | 4 | O=C(O)c1cccc(N2CCN3CCOc4cccc2c43)c1 | O=C(O)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | N2CC |
<|startoftext|><L>O=C(O)c1cccc(CN2CC<mask_1:3>CCOc4cccc2c43)c1<mask_1:3> | 2 | 18 | 3 | N3 | 3 | O=C(O)c1cccc(CN2CCN3CCCOc4cccc2c43)c1 | O=C(O)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | N3C |
<|startoftext|><L>O=C(O<mask_1:4>1cccc(CN2CCN3CCOc4cccc2c43)c1<mask_1:4> | 2 | 5 | 4 | )c | 4 | O=C(O)CCc1cccc(CN2CCN3CCOc4cccc2c43)c1 | O=C(O)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | )CCc |
<|startoftext|><L>O=C(O)c1cccc(CN2CCN3CC<mask_1:1>4cccc2c43)c1<mask_1:1> | 2 | 22 | 1 | Oc | 1 | O=C(O)c1cccc(CN2CCN3CCc4cccc2c43)c1 | O=C(O)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | c |
<|startoftext|><L>O=C(O)c1cccc(CN2CCN3<mask_1:2>cccc2c43)c1<mask_1:2> | 5 | 20 | 2 | CCOc4 | 2 | O=C(O)c1cccc(CN2CCN3c4cccc2c43)c1 | O=C(O)c1cccc(CN2CCN3CCOc4cccc2c43)c1 | c4 |
<|startoftext|><L>COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CC<mask_1:4>)c1<mask_1:4> | 3 | 46 | 4 | CO2 | 4 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCCO2)c1 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | CCO2 |
<|startoftext|><L>COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[<mask_1:2>@H]2CCCO2)c1<mask_1:2> | 1 | 39 | 2 | C | 2 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@@H]2CCCO2)c1 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | C@ |
<|startoftext|><L>COc1cccc(-c2nn<mask_1:7>3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1<mask_1:7> | 3 | 14 | 7 | (-c | 7 | COc1cccc(-c2nn(CN(C)c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | (CN(C)c |
<|startoftext|><L>COc1cccc(-c2nn(-c3ccc(C)cc3<mask_1:2>cc2C(=O)NC[C@H]2CCCO2)c1<mask_1:2> | 1 | 27 | 2 | ) | 2 | COc1cccc(-c2nn(-c3ccc(C)cc3C)cc2C(=O)NC[C@H]2CCCO2)c1 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | C) |
<|startoftext|><L>COc1cccc(-c2nn(-c3ccc(C)cc3)c<mask_1:6>(=O)NC[C@H]2CCCO2)c1<mask_1:6> | 3 | 29 | 6 | c2C | 6 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C=CC(=O)NC[C@H]2CCCO2)c1 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | c2C=CC |
<|startoftext|><L>COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC<mask_1:3>@H]2CCCO2)c1<mask_1:3> | 2 | 38 | 3 | [C | 3 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@@H]2CCCO2)c1 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | [C@ |
<|startoftext|><L>COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)N<mask_1:7>2CCCO2)c1<mask_1:7> | 6 | 37 | 7 | C[C@H] | 7 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@@H]2CCCO2)c1 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | C[C@@H] |
<|startoftext|><L>COc1cccc(-c2nn(-c3cc<mask_1:6>cc3)cc2C(=O)NC[C@H]2CCCO2)c1<mask_1:6> | 4 | 20 | 6 | c(C) | 6 | COc1cccc(-c2nn(-c3ccc(C#N)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | c(C#N) |
<|startoftext|><L>COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)<mask_1:3>C[C@H]2CCCO2)c1<mask_1:3> | 1 | 36 | 3 | N | 3 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NCCC[C@H]2CCCO2)c1 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | NCC |
<|startoftext|><L>COc<mask_1:6>cc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1<mask_1:6> | 3 | 3 | 6 | 1cc | 6 | COc1cc(C)cc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)NC[C@H]2CCCO2)c1 | 1cc(C) |
<|startoftext|><L>C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC<mask_1:5>)C(N)=S<mask_1:5> | 1 | 30 | 5 | 1 | 5 | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)N(C)C(N)=S | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | 1)N(C |
<|startoftext|><L>C[C@@H]<mask_1:3>Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S<mask_1:3> | 1 | 7 | 3 | ( | 3 | C[C@@H](NCCn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | (NC |
<|startoftext|><L>C[C@@H](Cn1nc(C(F)(F<mask_1:5>cc1C1CC1)C(N)=S<mask_1:5> | 3 | 20 | 5 | )F) | 5 | C[C@@H](Cn1nc(C(F)(F)F)cccc1C1CC1)C(N)=S | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | )F)cc |
<|startoftext|><L>C[<mask_1:2>H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S<mask_1:2> | 3 | 2 | 2 | C@@ | 2 | C[C@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | C@ |
<|startoftext|><L>C[C@@H](Cn1nc(<mask_1:2>F)F)cc1C1CC1)C(N)=S<mask_1:2> | 5 | 14 | 2 | C(F)( | 2 | C[C@@H](Cn1nc(C(F)F)cc1C1CC1)C(N)=S | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | C( |
<|startoftext|><L>C[C@@H](Cn1nc(C(F)(F)F)c<mask_1:3>C1CC1)C(N)=S<mask_1:3> | 2 | 24 | 3 | c1 | 3 | C[C@@H](Cn1nc(C(F)(F)F)cc1CC1CC1)C(N)=S | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | c1C |
<|startoftext|><L>C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1<mask_1:4>)C(N)=S<mask_1:4> | 0 | 31 | 4 | 4 | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)N(C)C(N)=S | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | )N(C |
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<|startoftext|><L>C[C@@<mask_1:5>(Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S<mask_1:5> | 2 | 5 | 5 | H] | 5 | C[C@@](O)C(Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | ](O)C |
<|startoftext|><L>C[C@<mask_1:3>n1nc(C(F)(F)F)cc1C1CC1)C(N)=S<mask_1:3> | 5 | 4 | 3 | @H](C | 3 | C[C@H](n1nc(C(F)(F)F)cc1C1CC1)C(N)=S | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | H]( |
<|startoftext|><L>C[C@@H](Cn1nc(C(F)(F)F)cc1C1C<mask_1:5>C(N)=S<mask_1:5> | 3 | 29 | 5 | C1) | 5 | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)NNC(N)=S | C[C@@H](Cn1nc(C(F)(F)F)cc1C1CC1)C(N)=S | C1)NN |
<|startoftext|><L>Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(C<mask_1:2>21<mask_1:2> | 4 | 31 | 2 | l)cc | 3 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(C)cc21 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | )cc |
<|startoftext|><L>Cc1ccncc1NC(=O)[C@H]1C<mask_1:4>cc(Cl)cc21<mask_1:4> | 5 | 22 | 4 | COc2c | 4 | Cc1ccncc1NC(=O)[C@H]1COc2ccc(Cl)cc21 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | Oc2c |
<|startoftext|><L>Cc1ccncc1NC(=O)[C@H]1CCOc2cc<mask_1:4>(Cl)cc21<mask_1:4> | 1 | 28 | 4 | c | 4 | Cc1ccncc1NC(=O)[C@H]1CCOc2cc(F)c(Cl)cc21 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | (F)c |
<|startoftext|><L>Cc1ccncc1NC<mask_1:4>=O)[C@H]1CCOc2ccc(Cl)cc21<mask_1:4> | 1 | 11 | 4 | ( | 4 | Cc1ccncc1NCCNC(=O)[C@H]1CCOc2ccc(Cl)cc21 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | CNC( |
<|startoftext|><L>Cc1ccnc<mask_1:5>(=O)[C@H]1CCOc2ccc(Cl)cc21<mask_1:5> | 4 | 7 | 5 | c1NC | 5 | Cc1ccncc1CNC(=O)[C@H]1CCOc2ccc(Cl)cc21 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | c1CNC |
<|startoftext|><L>Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)<mask_1:5>21<mask_1:5> | 2 | 33 | 5 | cc | 5 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)c(F)c21 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | c(F)c |
<|startoftext|><L>Cc1ccncc1NC(=O)[C@H]1CCOc2ccc<mask_1:4>Cl)cc21<mask_1:4> | 1 | 29 | 4 | ( | 4 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(OCCCl)cc21 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | (OCC |
<|startoftext|><L>Cc1<mask_1:1>ncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21<mask_1:1> | 2 | 3 | 1 | cc | 1 | Cc1oncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | o |
<|startoftext|><L>Cc1ccncc1NC<mask_1:3>[C@H]1CCOc2ccc(Cl)cc21<mask_1:3> | 4 | 11 | 3 | (=O) | 3 | Cc1ccncc1NCCOC[C@H]1CCOc2ccc(Cl)cc21 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | COC |
<|startoftext|><L>Cc1ccncc1NC(=O)[C@H<mask_1:2>Oc2ccc(Cl)cc21<mask_1:2> | 4 | 19 | 2 | ]1CC | 2 | Cc1ccncc1NC(=O)[C@H]1Oc2ccc(Cl)cc21 | Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21 | ]1 |