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<|startoftext|><L>COc1ccc(-n2nn<mask_1:5>=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1<mask_1:5> | 7 | 13 | 5 | nc2SCC( | 5 | COc1ccc(-n2nnnc2C(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | nc2C( |
<|startoftext|><L>COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O<mask_1:7>)cc1<mask_1:7> | 6 | 41 | 7 | )=O)c2 | 7 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2C)cc1 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | )=O)c2C |
<|startoftext|><L>COc1ccc(-n2nnnc<mask_1:7>CC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1<mask_1:7> | 2 | 15 | 7 | 2S | 8 | COc1ccc(-n2nnnc2SCC(=O)CC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | 2SCC(=O) |
<|startoftext|><L>COc1ccc(-n2nn<mask_1:4>(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1<mask_1:4> | 6 | 13 | 4 | nc2SCC | 4 | COc1ccc(-n2nnnc2C(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | nc2C |
<|startoftext|><L><mask_1:7>ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1<mask_1:7> | 4 | 0 | 7 | COc1 | 7 | CC(C)c1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | CC(C)c1 |
<|startoftext|><L>COc<mask_1:7>(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1<mask_1:7> | 4 | 3 | 7 | 1ccc | 7 | COc1cc(C)c(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | 1cc(C)c |
<|startoftext|><L>COc1ccc(-n2nnnc2<mask_1:2>Nc2ccc(C)c(S(N)(=O)=O)c2)cc1<mask_1:2> | 7 | 16 | 2 | SCC(=O) | 2 | COc1ccc(-n2nnnc2CCNc2ccc(C)c(S(N)(=O)=O)c2)cc1 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | CC |
<|startoftext|><L><mask_1:5>c(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1<mask_1:5> | 6 | 0 | 5 | COc1cc | 5 | Cc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | Cc1cc |
<|startoftext|><L><mask_1:6>COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1<mask_1:6> | 0 | 0 | 6 | 6 | NC(=O)COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | NC(=O) |
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<|startoftext|><L>COc1ccc(-n2n<mask_1:4>C(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1<mask_1:4> | 6 | 12 | 4 | nnc2SC | 4 | COc1ccc(-n2nnnc2C(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | COc1ccc(-n2nnnc2SCC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cc1 | nnc2 |
<|startoftext|><L>Cc1cccc(C(=O)Nc2ccc(F)c(Cl)<mask_1:3>1<mask_1:3> | 4 | 27 | 3 | c2)c | 4 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | c2)c |
<|startoftext|><L>Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c<mask_1:3>c1<mask_1:3> | 2 | 28 | 3 | 2) | 3 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2F)c1 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | 2F) |
<|startoftext|><L>Cc1cccc(C(=O)Nc2<mask_1:3>F)c(Cl)c2)c1<mask_1:3> | 4 | 16 | 3 | ccc( | 3 | Cc1cccc(C(=O)Nc2sc(F)c(Cl)c2)c1 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | sc( |
<|startoftext|><L>Cc1cccc(C(=O)<mask_1:1>Nc2ccc(F)c(Cl)c2)c1<mask_1:1> | 0 | 13 | 1 | 1 | Cc1cccc(C(=O)CNc2ccc(F)c(Cl)c2)c1 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | C |
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<|startoftext|><L>Cc1cccc<mask_1:3>(=O)Nc2ccc(F)c(Cl)c2)c1<mask_1:3> | 2 | 7 | 3 | (C | 3 | Cc1cccc(CC(=O)Nc2ccc(F)c(Cl)c2)c1 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | (CC |
<|startoftext|><L>Cc1cccc(C(=O<mask_1:2>Nc2ccc(F)c(Cl)c2)c1<mask_1:2> | 1 | 12 | 2 | ) | 2 | Cc1cccc(C(=O)NNc2ccc(F)c(Cl)c2)c1 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | )N |
<|startoftext|><L>Cc1ccc<mask_1:3>C(=O)Nc2ccc(F)c(Cl)c2)c1<mask_1:3> | 2 | 6 | 3 | c( | 3 | Cc1cccc(CC(=O)Nc2ccc(F)c(Cl)c2)c1 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | c(C |
<|startoftext|><L>C<mask_1:4>cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1<mask_1:4> | 2 | 1 | 4 | c1 | 4 | CCOc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | COc1 |
<|startoftext|><L>Cc1cccc(C(=O)Nc2ccc(F)c(<mask_1:4>c2)c1<mask_1:4> | 3 | 24 | 4 | Cl) | 4 | Cc1cccc(C(=O)Nc2ccc(F)c(C#N)c2)c1 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | C#N) |
<|startoftext|><L>Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2<mask_1:3>1<mask_1:3> | 2 | 29 | 3 | )c | 3 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2F)c1 | Cc1cccc(C(=O)Nc2ccc(F)c(Cl)c2)c1 | F)c |
<|startoftext|><L>C[C@@H]1CCN(C(=O)C2CCC(c3ccccc<mask_1:3>CC2)CCS1(=O)=O<mask_1:3> | 2 | 30 | 3 | 3) | 3 | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CCC2)CCS1(=O)=O | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | 3)C |
<|startoftext|><L>C[C@@H]1CCN(C<mask_1:4>CCC(c3ccccc3)CC2)CCS1(=O)=O<mask_1:4> | 6 | 13 | 4 | (=O)C2 | 4 | C[C@@H]1CCN(CCCN2CCC(c3ccccc3)CC2)CCS1(=O)=O | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | CCN2 |
<|startoftext|><L>C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O<mask_1:1>O<mask_1:1> | 2 | 43 | 1 | )= | 1 | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)O | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | ) |
<|startoftext|><L>C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CC<mask_1:3>O)=O<mask_1:3> | 4 | 38 | 3 | S1(= | 3 | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(O)=O | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | S1( |
<|startoftext|><L>C[C@@H]1CCN(<mask_1:4>C2CCC(c3ccccc3)CC2)CCS1(=O)=O<mask_1:4> | 5 | 12 | 4 | C(=O) | 4 | C[C@@H]1CCN(CCCNC2CCC(c3ccccc3)CC2)CCS1(=O)=O | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | CCCN |
<|startoftext|><L>C[C@@H]1CCN(C(=O)C2CCC(c3<mask_1:4>3)CC2)CCS1(=O)=O<mask_1:4> | 5 | 25 | 4 | ccccc | 5 | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | ccccc |
<|startoftext|><L>C[C@@<mask_1:1>1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O<mask_1:1> | 2 | 5 | 1 | H] | 1 | C[C@@]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | ] |
<|startoftext|><L>C[C@@H]1CCN(C(=O)C2CCC(c3cc<mask_1:5>c3)CC2)CCS1(=O)=O<mask_1:5> | 2 | 27 | 5 | cc | 5 | C[C@@H]1CCN(C(=O)C2CCC(c3ccc(O)cc3)CC2)CCS1(=O)=O | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | c(O)c |
<|startoftext|><L>C[C@@H]<mask_1:4>C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O<mask_1:4> | 5 | 7 | 4 | 1CCN( | 4 | C[C@@H]1CN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | 1CN( |
<|startoftext|><L>C[C<mask_1:4>CN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O<mask_1:4> | 6 | 3 | 4 | @@H]1C | 4 | C[C@H]1CN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | C[C@@H]1CCN(C(=O)C2CCC(c3ccccc3)CC2)CCS1(=O)=O | @H]1 |
<|startoftext|><L>COC(=O<mask_1:5>c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1<mask_1:5> | 1 | 6 | 5 | ) | 5 | COC(=O)/C=Cc1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | )/C=C |
<|startoftext|><L>COC(=O)c1cc2ccccc2c(<mask_1:3>(C(N)=O)CC2)n1<mask_1:3> | 5 | 20 | 3 | N2CCC | 3 | COC(=O)c1cc2ccccc2c(N2C(C(N)=O)CC2)n1 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | N2C |
<|startoftext|><L>COC(=O)c1cc2ccccc2c(N2C<mask_1:1>CC(C(N)=O)CC2)n1<mask_1:1> | 0 | 23 | 1 | 1 | COC(=O)c1cc2ccccc2c(N2CCCC(C(N)=O)CC2)n1 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | C |
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<|startoftext|><L>COC(=O)c1cc2ccccc2c(N2CCC(<mask_1:2>(N)=O)CC2)n1<mask_1:2> | 1 | 26 | 2 | C | 2 | COC(=O)c1cc2ccccc2c(N2CCC(CC(N)=O)CC2)n1 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | CC |
<|startoftext|><L>COC(=O)c1cc2c<mask_1:2>c2c(N2CCC(C(N)=O)CC2)n1<mask_1:2> | 3 | 13 | 2 | ccc | 2 | COC(=O)c1cc2ccsc2c(N2CCC(C(N)=O)CC2)n1 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | cs |
<|startoftext|><L>COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC<mask_1:2>)n1<mask_1:2> | 1 | 35 | 2 | 2 | 2 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CCC2)n1 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | C2 |
<|startoftext|><L>COC(=O)c1cc2ccccc2c(N2CCC(C<mask_1:1>O)CC2)n1<mask_1:1> | 4 | 27 | 1 | (N)= | 1 | COC(=O)c1cc2ccccc2c(N2CCC(CCO)CC2)n1 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | C |
<|startoftext|><L>COC(=O)c1cc2ccccc2c(N2C<mask_1:1>CC(C(N)=O)CC2)n1<mask_1:1> | 0 | 23 | 1 | 1 | COC(=O)c1cc2ccccc2c(N2CCCC(C(N)=O)CC2)n1 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | C |
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<|startoftext|><L>COC(=O)c1cc2ccccc2c(N2<mask_1:3>C(N)=O)CC2)n1<mask_1:3> | 4 | 22 | 3 | CCC( | 3 | COC(=O)c1cc2ccccc2c(N2CC(C(N)=O)CC2)n1 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | CC( |
<|startoftext|><L>COC(=O)c1cc2<mask_1:4>cccc2c(N2CCC(C(N)=O)CC2)n1<mask_1:4> | 1 | 12 | 4 | c | 4 | COC(=O)c1cc2c(O)cccc2c(N2CCC(C(N)=O)CC2)n1 | COC(=O)c1cc2ccccc2c(N2CCC(C(N)=O)CC2)n1 | c(O) |
<|startoftext|><L>Cc1cc(C(=O)NC[C@@H<mask_1:5>ccc3O2)c(C)n1-c1cccnc1<mask_1:5> | 7 | 18 | 5 | ]2Cc3cc | 5 | Cc1cc(C(=O)NC[C@@H]2c3sccc3O2)c(C)n1-c1cccnc1 | Cc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | ]2c3s |
<|startoftext|><L>Cc1cc(C(=O)NC<mask_1:5>2Cc3ccccc3O2)c(C)n1-c1cccnc1<mask_1:5> | 6 | 13 | 5 | [C@@H] | 5 | Cc1cc(C(=O)NC[C@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | Cc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | [C@H] |
<|startoftext|><L>Cc1<mask_1:6>(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1<mask_1:6> | 4 | 3 | 6 | cc(C | 6 | Cc1cc(CNC(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | Cc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | cc(CNC |
<|startoftext|><L><mask_1:4>cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1<mask_1:4> | 3 | 0 | 4 | Cc1 | 4 | CCc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | Cc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | CCc1 |
<|startoftext|><L>Cc1cc(C(=O)NC[C<mask_1:4>c3ccccc3O2)c(C)n1-c1cccnc1<mask_1:4> | 6 | 15 | 4 | @@H]2C | 4 | Cc1cc(C(=O)NC[CH]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | Cc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | H]2C |
<|startoftext|><L>Cc1cc(C(<mask_1:7>=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1<mask_1:7> | 0 | 8 | 7 | 7 | Cc1cc(C(=O)NCC(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | Cc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | =O)NCC( |
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<|startoftext|><L>Cc1cc(C(=O)<mask_1:6>]2Cc3ccccc3O2)c(C)n1-c1cccnc1<mask_1:6> | 7 | 11 | 6 | NC[C@@H | 6 | Cc1cc(C(=O)NC[C@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | Cc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | NC[C@H |
<|startoftext|><L>Cc1cc(C(=O)NC[C@@H]2Cc3c<mask_1:6>ccc3O2)c(C)n1-c1cccnc1<mask_1:6> | 1 | 24 | 6 | c | 6 | Cc1cc(C(=O)NC[C@@H]2Cc3cc(C#N)ccc3O2)c(C)n1-c1cccnc1 | Cc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | c(C#N) |
<|startoftext|><L>Cc1cc(C(=O)NC<mask_1:3>Cc3ccccc3O2)c(C)n1-c1cccnc1<mask_1:3> | 7 | 13 | 3 | [C@@H]2 | 3 | Cc1cc(C(=O)NCC2=Cc3ccccc3O2)c(C)n1-c1cccnc1 | Cc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | C2= |
<|startoftext|><L>Cc1cc(C(=O)NC[C@@H]2Cc3ccc<mask_1:5>cc3O2)c(C)n1-c1cccnc1<mask_1:5> | 0 | 26 | 5 | 5 | Cc1cc(C(=O)NC[C@@H]2Cc3ccc(C#N)cc3O2)c(C)n1-c1cccnc1 | Cc1cc(C(=O)NC[C@@H]2Cc3ccccc3O2)c(C)n1-c1cccnc1 | (C#N) |
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<|startoftext|><L>CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=<mask_1:5>[C@@H]2C1<mask_1:5> | 2 | 42 | 5 | O) | 5 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)NCC[C@@H]2C1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | O)NCC |
<|startoftext|><L>CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)<mask_1:6>]2C1<mask_1:6> | 5 | 44 | 6 | [C@@H | 5 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | [C@@H |
<|startoftext|><L>CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS<mask_1:1>(=O)[C@@H]2C1<mask_1:1> | 4 | 36 | 1 | (=O) | 1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CSC(=O)[C@@H]2C1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | C |
<|startoftext|><L>CC<mask_1:7>(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1<mask_1:7> | 0 | 2 | 7 | 7 | CCOC[C@H](C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | OC[C@H] |
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<|startoftext|><L>CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3<mask_1:7>(=O)(=O)[C@@H]2C1<mask_1:7> | 2 | 34 | 7 | CS | 7 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)S(=O)(=O)[C@@H]2C1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | CS(=O)S |
<|startoftext|><L>CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=<mask_1:3>[C@@H]2C1<mask_1:3> | 2 | 42 | 3 | O) | 3 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)C[C@@H]2C1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | O)C |
<|startoftext|><L>CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@<mask_1:4>1<mask_1:4> | 5 | 47 | 4 | @H]2C | 4 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@H]2C1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | H]2C |
<|startoftext|><L>CC(C)CN1C[C@@H]2c3nc(N<mask_1:5>OCC4)ncc3CS(=O)(=O)[C@@H]2C1<mask_1:5> | 3 | 22 | 5 | 4CC | 5 | CC(C)CN1C[C@@H]2c3nc(NCC4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | CC4CC |
<|startoftext|><L>CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)<mask_1:3>2C1<mask_1:3> | 6 | 44 | 3 | [C@@H] | 3 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C]2C1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | [C] |
<|startoftext|><L>CC(C)CN1C[C@@H]2c3nc(<mask_1:6>COCC4)ncc3CS(=O)(=O)[C@@H]2C1<mask_1:6> | 3 | 21 | 6 | N4C | 6 | CC(C)CN1C[C@@H]2c3nc(NCCN4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | CC(C)CN1C[C@@H]2c3nc(N4CCOCC4)ncc3CS(=O)(=O)[C@@H]2C1 | NCCN4C |
<|startoftext|><L>O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1<mask_1:5>nH]c(=O)c2ccccc12<mask_1:5> | 2 | 29 | 5 | n[ | 5 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1c(O)[nH]c(=O)c2ccccc12 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | c(O)[ |
<|startoftext|><L>O=<mask_1:6>ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12<mask_1:6> | 5 | 2 | 6 | C(Nc1 | 6 | O=C(NCc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | C(NCc1 |
<|startoftext|><L><mask_1:7>(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12<mask_1:7> | 3 | 0 | 7 | O=C | 7 | C[C@@H](Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | C[C@@H] |
<|startoftext|><L>O=C(Nc1ccc(NC(=O)C2CC2)nc1<mask_1:7>1n[nH]c(=O)c2ccccc12<mask_1:7> | 2 | 26 | 7 | )c | 7 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)C(=O)c1n[nH]c(=O)c2ccccc12 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | )C(=O)c |
<|startoftext|><L>O=C(Nc1cc<mask_1:6>)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12<mask_1:6> | 7 | 9 | 6 | c(NC(=O | 6 | O=C(Nc1ccc(CN(C)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | c(CN(C |
<|startoftext|><L>O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccc<mask_1:5>12<mask_1:5> | 2 | 44 | 5 | cc | 5 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2cccc(F)c12 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | c(F)c |
<|startoftext|><L>O=C(Nc1ccc(NC(=O)C2CC2<mask_1:3>)c1n[nH]c(=O)c2ccccc12<mask_1:3> | 4 | 22 | 3 | )nc1 | 3 | O=C(Nc1ccc(NC(=O)C2CC2)s1)c1n[nH]c(=O)c2ccccc12 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | )s1 |
<|startoftext|><L>O=C(Nc1ccc(NC(=O)C2CC2)nc1)<mask_1:4>n[nH]c(=O)c2ccccc12<mask_1:4> | 2 | 27 | 4 | c1 | 4 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)OCc1n[nH]c(=O)c2ccccc12 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | OCc1 |
<|startoftext|><L>O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n<mask_1:3>(=O)c2ccccc12<mask_1:3> | 5 | 30 | 3 | [nH]c | 3 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1nccc(=O)c2ccccc12 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | ccc |
<|startoftext|><L><mask_1:3>C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12<mask_1:3> | 2 | 0 | 3 | O= | 3 | O=NC(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1n[nH]c(=O)c2ccccc12 | O=N |
<|startoftext|><L><mask_1:8>l)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O<mask_1:8> | 9 | 0 | 8 | COc1ccc(C | 8 | Cc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | Cc1ccc(C |
<|startoftext|><L>COc1ccc(Cl)cc1N1C(=O)C[C<mask_1:10>2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O<mask_1:10> | 6 | 24 | 10 | @@H](N | 10 | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N(C)C2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | @@H](N(C)C |
<|startoftext|><L>COc1ccc(Cl)cc1N1C(=O<mask_1:4>[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O<mask_1:4> | 2 | 20 | 4 | )C | 4 | COc1ccc(Cl)cc1N1C(=O)CCC[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | )CCC |
<|startoftext|><L>COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H<mask_1:6>3COc4ccccc4O3)CC2)C1=O<mask_1:6> | 1 | 44 | 6 | ] | 6 | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H](C)OC3COc4ccccc4O3)CC2)C1=O | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | ](C)OC |
<|startoftext|><L>COc1ccc(Cl)cc1N1C(=O)C[C@@H](<mask_1:2>2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O<mask_1:2> | 1 | 29 | 2 | N | 2 | COc1ccc(Cl)cc1N1C(=O)C[C@@H](NC2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | NC |
<|startoftext|><L>COc1ccc(Cl)cc<mask_1:3>1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O<mask_1:3> | 2 | 13 | 3 | 1N | 3 | COc1ccc(Cl)cc1NC1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | 1NC |
<|startoftext|><L>COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@<mask_1:3>c4ccccc4O3)CC2)C1=O<mask_1:3> | 5 | 43 | 3 | H]3CO | 3 | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3c4ccccc4O3)CC2)C1=O | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | H]3 |
<|startoftext|><L>COc1c<mask_1:10>c1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O<mask_1:10> | 7 | 5 | 10 | cc(Cl)c | 10 | COc1ccc(Cl)c(C)c1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | cc(Cl)c(C) |
<|startoftext|><L>COc1ccc(Cl)cc1N1C(=O<mask_1:10>H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O<mask_1:10> | 6 | 20 | 10 | )C[C@@ | 10 | COc1ccc(Cl)cc1N1C(=O)C(=O)C[C@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | )C(=O)C[C@ |
<|startoftext|><L>COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3C<mask_1:9>cc4O3)CC2)C1=O<mask_1:9> | 6 | 47 | 9 | Oc4ccc | 9 | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4cc(C)ccc4O3)CC2)C1=O | COc1ccc(Cl)cc1N1C(=O)C[C@@H](N2CCN(C(=O)[C@H]3COc4ccccc4O3)CC2)C1=O | Oc4cc(C)c |
<|startoftext|><L>C[C@H](<mask_1:6>ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1<mask_1:6> | 3 | 7 | 6 | Cc1 | 6 | C[C@H](CCOCc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | CCOCc1 |
<|startoftext|><L>C[C@H](C<mask_1:4>ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1<mask_1:4> | 2 | 8 | 4 | c1 | 4 | C[C@H](CCCc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | CCc1 |
<|startoftext|><L>C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2C<mask_1:3>N(C)CC2)c1<mask_1:3> | 1 | 32 | 3 | C | 3 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCCCN(C)CC2)c1 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | CCC |
<|startoftext|><L>C[C@H](<mask_1:6>Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1<mask_1:6> | 0 | 7 | 6 | 6 | C[C@H](C(=O)NCc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | C(=O)N |
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<|startoftext|><L>C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)<mask_1:6>2)c1<mask_1:6> | 2 | 37 | 6 | CC | 6 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)C(=O)C2)c1 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | C(=O)C |
<|startoftext|><L>C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2<mask_1:2>)c1<mask_1:2> | 0 | 40 | 2 | 2 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2=O)c1 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | =O |
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<|startoftext|><L>C[C@H](Cc1ccco1<mask_1:5>=O)c1ccnc(N2CCN(C)CC2)c1<mask_1:5> | 4 | 15 | 5 | )NC( | 5 | C[C@H](Cc1ccco1)CNC(=O)c1ccnc(N2CCN(C)CC2)c1 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | )CNC( |
<|startoftext|><L>C[C<mask_1:4>(Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1<mask_1:4> | 3 | 3 | 4 | @H] | 4 | C[C@@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | @@H] |
<|startoftext|><L>C[C@H](Cc1ccco1)NC(=O)c1<mask_1:3>(N2CCN(C)CC2)c1<mask_1:3> | 4 | 24 | 3 | ccnc | 3 | C[C@H](Cc1ccco1)NC(=O)c1nsc(N2CCN(C)CC2)c1 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | nsc |
<|startoftext|><L>C[C@H](Cc1ccco1)NC(=O)c1ccn<mask_1:5>c(N2CCN(C)CC2)c1<mask_1:5> | 0 | 27 | 5 | 5 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(=O)c(N2CCN(C)CC2)c1 | C[C@H](Cc1ccco1)NC(=O)c1ccnc(N2CCN(C)CC2)c1 | c(=O) |
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<|startoftext|><L>CCn1<mask_1:4>c2ccc([C@@H](C)O)cc2)n[nH]c1=O<mask_1:4> | 3 | 4 | 4 | c(S | 4 | CCn1c(COc2ccc([C@@H](C)O)cc2)n[nH]c1=O | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | c(CO |
<|startoftext|><L><mask_1:2>Cn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O<mask_1:2> | 1 | 0 | 2 | C | 2 | CCCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | CC |
<|startoftext|><L>CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1<mask_1:2>=O<mask_1:2> | 0 | 35 | 2 | 2 | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=S=O | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | =S |
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<|startoftext|><L>CCn1c(Sc2ccc([<mask_1:3>](C)O)cc2)n[nH]c1=O<mask_1:3> | 4 | 14 | 3 | C@@H | 3 | CCn1c(Sc2ccc([C@H](C)O)cc2)n[nH]c1=O | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | C@H |
<|startoftext|><L>CC<mask_1:5>c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O<mask_1:5> | 2 | 2 | 5 | n1 | 5 | CC(C)n1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | (C)n1 |
<|startoftext|><L>CCn1c(Sc2ccc([C@@H](C)O)cc2)n<mask_1:1>c1=O<mask_1:1> | 4 | 29 | 1 | [nH] | 1 | CCn1c(Sc2ccc([C@@H](C)O)cc2)noc1=O | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | o |
<|startoftext|><L>CCn1c(Sc2ccc([C@@H]<mask_1:4>)O)cc2)n[nH]c1=O<mask_1:4> | 2 | 19 | 4 | (C | 4 | CCn1c(Sc2ccc([C@@H](C#N)O)cc2)n[nH]c1=O | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | (C#N |
<|startoftext|><L>CCn1c(Sc2ccc([C@@H<mask_1:4>)O)cc2)n[nH]c1=O<mask_1:4> | 3 | 18 | 4 | ](C | 4 | CCn1c(Sc2ccc([C@@H](CC)O)cc2)n[nH]c1=O | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | ](CC |
<|startoftext|><L>CCn1c(S<mask_1:2>c2ccc([C@@H](C)O)cc2)n[nH]c1=O<mask_1:2> | 0 | 7 | 2 | 2 | CCn1c(SCCc2ccc([C@@H](C)O)cc2)n[nH]c1=O | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | CC |
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<|startoftext|><L>CCn1c(Sc2ccc([C@@H<mask_1:3>C)O)cc2)n[nH]c1=O<mask_1:3> | 2 | 18 | 3 | ]( | 3 | CCn1c(Sc2ccc([C@@H](CC)O)cc2)n[nH]c1=O | CCn1c(Sc2ccc([C@@H](C)O)cc2)n[nH]c1=O | ](C |