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The study lasts approximately 40 weeks separated into a screening, treatment, and follow-up phase. Researchers determine if it is safe for the you to receive the drug and if you are eligible for the study during Screening. If eligible for the study, the treatment phase lasts 24 weeks (or six months) with one follow-up ... |
During the treatment phase, participants will be asked to come to clinic every two weeks for the first month of treatment, and monthly thereafter for a total of eight treatment visits. Participants will be asked to: |
* Complete questionnaires asking about the effect of HS in their daily lives and their perception of HS and treatment received. |
* Receive related medical evaluation |
* Receive the study drug intravenously |
* Stay 20 minutes after the infusion for monitoring conditions: Hidradenitis Suppurativa conditions: Acne Inversa conditions: Hidradenitis studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: All study participants, if eligible, will receive the study dru... |
<|newrecord|> nctId: NCT06374199 id: 24-0181 briefTitle: Med-South Lifestyle Program for Pregnancy overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-01 date: 2025-01 date: 2024-04-18 date: 2024-04-18 name: University of North Carolina, Chapel Hill class: OTHER briefSummary: Eating a Mediterranean-style diet du... |
The purpose of this study is to assess the feasibility and acceptability of a Food is Medicine intervention when started during the first trimester of pregnancy. The eating pattern to be evaluated in this study is a Mediterranean-style dietary pattern adapted for the southern United States - thus, the program is called... |
<|newrecord|> nctId: NCT06374186 id: 2095072 id: 2095072 type: OTHER domain: UMKC IRB briefTitle: Continuous Glucose Monitoring, Contingency Management, and Motivational Interviewing for Patients With Type 2 Diabetes in Kansas City acronym: COMMITTED2-KC overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-12-... |
<|newrecord|> nctId: NCT06374173 id: TGI6-T1-01 briefTitle: A Phase 1 Study to Evaluate TGI-6 in Subjects With Locally Advanced/Metastatic Solid Tumors overallStatus: RECRUITING date: 2024-01-03 date: 2027-09 date: 2027-12 date: 2024-04-18 date: 2024-04-18 name: Hefei TG ImmunoPharma Co., Ltd. class: OTHER briefSummary... |
<|newrecord|> nctId: NCT06374160 id: 70115371 briefTitle: Exercise in Patients With Advanced Non-small Cell Lung Cancer acronym: BREATH overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-04-30 date: 2026-08-31 date: 2024-04-18 date: 2024-04-18 name: University Hospital, Essen class: OTHER name: German Cancer... |
The BREATH-study is a prospective 3-arm randomized controlled trial (RCT). In total, the investigators plan to recruit 104 patients. A 2:1:1 randomization will be performed with three study groups: a control group and two exercise therapy groups (strength+endurance exercise/only endurance exercise). One group receives ... |
The primary aim is to investigate the impact of exercise on V02peak. Secondarily endpoints aim to investigate changes in physical function, patient related outcomes and cardiac function before and after exercise. conditions: Advanced Lung Carcinoma conditions: First Line Treatment conditions: Second Line Treatment cond... |
<|newrecord|> nctId: NCT06374147 id: STUDY00004467 briefTitle: "Prapela® SVS Incubator Pad for Apnea of Prematurity acronym: Prapela AOP overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2026-06-01 date: 2026-12-31 date: 2024-04-18 date: 2024-04-18 name: Tufts Medical Center class: OTHER name: University of Alab... |
<|newrecord|> nctId: NCT06374134 id: STUDY00004835 briefTitle: The Impact of Community and Patient Engagement Practices on Vaccine Confidence in the United States overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2024-11 date: 2025-02 date: 2024-04-18 date: 2024-04-18 name: Tufts University class: OTHER name: Merck... |
Our hypothesis is that patient-centric clinical trial activity, and community engagement in late-stage clinical trials and early-stage commercialization, reduces vaccine hesitancy and increases vaccine confidence among health care providers overall and within diverse patient communities and ultimately drives faster vac... |
<|newrecord|> nctId: NCT06374121 id: POWER briefTitle: Kidney Perfusion With or Without Absorption acronym: POWER overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-06 date: 2026-06 date: 2024-04-18 date: 2024-04-18 name: Mario Negri Institute for Pharmacological Research class: OTHER briefSummary: In this sing... |
<|newrecord|> nctId: NCT06374108 id: Neuro_Exercise briefTitle: Resistance Training and Corticospinal Excitability in Multiple Sclerosis acronym: NEXIMS overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-12-31 date: 2026-05-31 date: 2024-04-18 date: 2024-04-29 name: University of Aarhus class: OTHER name: Aa... |
<|newrecord|> nctId: NCT06374095 id: ONSET briefTitle: 1 vs 7 RATG Infusions in Renal Transplantation acronym: ONSET overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-06 date: 2025-06 date: 2024-04-18 date: 2024-04-18 name: Mario Negri Institute for Pharmacological Research class: OTHER briefSummary: This tria... |
<|newrecord|> nctId: NCT06374082 id: HKWC-2024-179 briefTitle: Instant Messaging Reinforcement for Smoking Cessation Counseling Training overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-08 date: 2024-10 date: 2024-04-18 date: 2024-04-18 name: The University of Hong Kong class: OTHER briefSummary: This researc... |
The study is a pragmatic randomized controlled trial (RCT) with a 1:1 allocation ratio, using WhatsApp Messenger (WhatsApp) messages for intervention and control groups. The intervention group receives messages related to SCC, while the control group receives generic mental health information. The subjects are MN stude... |
The study uses various tools for measurement, including Ecological momentary assessment (EMA) and Providers Smoking Cessation Training Evaluation (ProSCiTE). The main outcome measures include SCC practice frequency, SCC knowledge score, SCC attitude score, and SCC practice score. |
Data analysis will be performed in Statistical Package for the Social Sciences (SPSS), using descriptive statistics, intention-to-treat analysis, Chi-square and t-tests, Cohen's d for effect size, and linear mixed models. The expected results suggest that instant messaging reinforcement will enhance SCC knowledge, atti... |
<|newrecord|> nctId: NCT06374069 id: NL81887.058.23 briefTitle: Longevity Families of the Netherlands acronym: LOF-NL overallStatus: RECRUITING date: 2023-09-11 date: 2026-12 date: 2026-12 date: 2024-04-18 date: 2024-04-18 name: Leiden University Medical Center class: OTHER name: Jacobijn Gussekloo, Prof. dr. name: Sim... |
The purpose of our research is: to identify gene variants associated with healthy aging and protection from (multi)morbidity; to study the social-, environment- and behavioral factors of familial longevity, their role in (multi-)morbidity and its interaction with the genetic component. conditions: Longevity conditions:... |
<|newrecord|> nctId: NCT06374056 id: 0458 briefTitle: Kintsugi Voice Device Pilot Study overallStatus: RECRUITING date: 2024-03-22 date: 2025-03-22 date: 2025-07-22 date: 2024-04-18 date: 2024-04-19 name: Kintsugi Mindful Wellness, Inc. class: INDUSTRY name: Sonar Strategies name: Vituity Psychiatry briefSummary: A pro... |
<|newrecord|> nctId: NCT06374043 id: 2020/1002 briefTitle: Decentralized N=1 Study: A Feasible Approach to Evaluate Individual Therapy Response to Dapagliflozin. acronym: @HOME overallStatus: COMPLETED date: 2021-05-11 date: 2022-09-13 date: 2022-09-13 date: 2024-04-18 date: 2024-04-22 name: University Medical Center G... |
The goal of this clinical trial is to determine the individual response to the SGLT2 inhibitor dapagliflozin in urine albumin-to-creatinine ratio (UACR). Secondary objectives are to determine the individual response to dapagliflozin in systolic blood pressure, body weight, eGFR, and fasting plasma glucose. |
Participants will collect all study data in the comfort of their own environments: |
* First-morning void urine samples |
* Capillary blood samples |
* Blood pressure |
* Body weight |
Participants will be randomly assigned to a cross-over study consisting of two periods of 1-week treatment with dapagliflozin 10 mg/day and two periods of 1-week treatment with placebo in random order with a 1-week wash-out period between every treatment period to avoid cross-over effects. conditions: Diabetes Mellitus... |
<|newrecord|> nctId: NCT06374030 id: EDSAM2024 briefTitle: Retrospective Study of Airway Management in Dutch ED's overallStatus: ACTIVE_NOT_RECRUITING date: 2019-01-01 date: 2023-12-31 date: 2024-12-31 date: 2024-04-18 date: 2024-04-18 name: Medical Centre Leeuwarden class: OTHER name: VieCuri Medical Centre name: Cath... |
<|newrecord|> nctId: NCT06374017 id: N-258-2023 briefTitle: Evaluation of Lidocaine Spray Versus Dexmetomidine Spray on Stress Response overallStatus: RECRUITING date: 2023-09-20 date: 2024-04-30 date: 2024-05-10 date: 2024-04-18 date: 2024-04-18 name: Kasr El Aini Hospital class: OTHER briefSummary: Many studies discu... |
<|newrecord|> nctId: NCT06374004 id: HU-FTR-MC-01 briefTitle: The Effect of Thoracic Mobilization in Individuals With Subacromial Pain Syndrome overallStatus: ENROLLING_BY_INVITATION date: 2024-04-10 date: 2024-07-05 date: 2024-07-05 date: 2024-04-18 date: 2024-04-18 name: Hacettepe University class: OTHER briefSummary... |
<|newrecord|> nctId: NCT06373991 id: EDI-901-SLE01 briefTitle: A Study to Evaluate the Safety and Efficacy of ATHENA CAR-T in Subjects With Systemic Lupus Erythematosus overallStatus: RECRUITING date: 2024-04-24 date: 2027-04-30 date: 2027-04-30 date: 2024-04-18 date: 2024-04-29 name: EdiGene Inc. class: INDUSTRY name:... |
• To evaluate the safety and tolerability of ATHENA CAR-T. |
After screening, participants will be subjected to lymphodepletion regimen. After recovery, participants will be injected with ATHENA CAR-T injection and followed up to 24 months. conditions: Lupus Erythematosus, Systemic studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SINGLE_GROUP primaryPur... |
<|newrecord|> nctId: NCT06373978 id: 24-307 briefTitle: NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-06-01 date: 2025-12-01 date: 2024-04-18 date: 2024-04-18 name: The Cleveland Clinic class: OTHER briefSummary: This study is a double-bl... |
The primary objective of this study is to illustrate a reduction in the consumption of narcotic pills following a percutaneous needle tenotomy procedure on the lateral elbow. |
The secondary aim is to assess the proportion of patients who have been randomly assigned to Diclofenac and successfully refrain from using the Tramadol rescue medication, measured at the 10 day (+/- 4 days) postoperative mark. |
The third objective is to uphold consistent early recovery outcomes as measured by the Patient-Rated Tennis Elbow Evaluation (PRTEE) and Quick Disability of Arm, Shoulder, and Hand (QuickDASH) scores after percutaneous needle tenotomy of the lateral elbow, while also investigating the relationship between resiliency an... |
<|newrecord|> nctId: NCT06373965 id: B2024-000 briefTitle: Integrated Online-to-offline (O2O) Model of Care for HIV Prevention and Treatment Among Transgender Women (CINTAI) overallStatus: NOT_YET_RECRUITING date: 2024-05-19 date: 2025-01-06 date: 2025-02-18 date: 2024-04-18 date: 2024-04-18 name: University of Connect... |
<|newrecord|> nctId: NCT06373952 id: 23-08-658-910 briefTitle: Integrated Online-to-offline (O2O) Model of Care for HIV Prevention and Treatment Among Men Who Have Sex With Men acronym: CINTAI overallStatus: NOT_YET_RECRUITING date: 2024-05-19 date: 2025-01-06 date: 2025-02-18 date: 2024-04-18 date: 2024-04-22 name: Un... |
<|newrecord|> nctId: NCT06373939 id: Pneumoscope study briefTitle: Performance and Safety of the Pneumoscope Device in Adults and Children overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-12-31 date: 2024-12-31 date: 2024-04-18 date: 2024-04-18 name: Pediatric Clinical Research Platform class: OTHER name: ... |
<|newrecord|> nctId: NCT06373926 id: PI2019_843_0010 briefTitle: Evaluation of Cell Membrane Expression of Annexin A2 on Monocytes by Flow Cytometry in Primary Antiphospholipid Syndrome acronym: MONOCYTAN overallStatus: RECRUITING date: 2023-03-28 date: 2025-03 date: 2025-03 date: 2024-04-18 date: 2024-04-18 name: Cent... |
<|newrecord|> nctId: NCT06373913 id: MASP2NSRZL briefTitle: The Role of Proprotein-convertase-subtilisin/Kexin-type 9 in Kidney Damage in Nephrotic Syndrom acronym: PCSK9 overallStatus: RECRUITING date: 2023-06-01 date: 2027-07-30 date: 2028-07-30 date: 2024-04-18 date: 2024-04-18 name: Kolding Sygehus class: OTHER nam... |
The study aim is to investigate the role of the protein convertase subtilisin/kexin type 9 (PCSK9) in hyperlipidemia of NS, which has been suggested to play an important role. This is done by testing the following hypotheses: |
1. PCSK9 is increased in patients with NS and hyperlipidemia compared to kidney-healthy controls |
2. The level of PCSK9 in plasma correlates to the degree of proteinuria. |
3. PCSK9 i increased in the kidney tissue of patients with NS |
The study will compare plasma levels of PCSK9 in correlation with degree of protein in the urine between test persons with NS and kidney healthy controls. Furthermore the investigators will study the the degree of PCSK9 in the kidney in biopsies obtained from test persons with nephrotic syndrome and test persons withou... |
<|newrecord|> nctId: NCT06373900 id: IndusH briefTitle: Wound Closure After Total Knee Arthroplasty: Comparison of Polypropylene and Polyglactin 910 Suture. overallStatus: COMPLETED date: 2022-02-13 date: 2022-02-19 date: 2022-03-30 date: 2024-04-18 date: 2024-04-18 name: Indus Hospital and Health Network class: OTHER ... |
<|newrecord|> nctId: NCT06373887 id: 2023-09-005A briefTitle: The Efficacy of Weight-loss Diet Decision-making Based on Initial Gut Metabolic Modules (GMMs) overallStatus: RECRUITING date: 2024-04-10 date: 2024-11-29 date: 2024-12-31 date: 2024-04-18 date: 2024-04-18 name: Taipei Veterans General Hospital, Taiwan class... |
Based on the above research, we designed a low-carb diet (rich in monounsaturated fatty acids) and a low-fat diet (whole grains) with the same calories as a means of weight loss. The primary purpose of this study is to evaluate the pre-GMM test for determines the weight loss benefit of the intervention diet. Furthermor... |
<|newrecord|> nctId: NCT06373874 id: MCBU-SBF-YC-04 briefTitle: The Effect of High Reality Simulation Environment on the Skills of Midwifery Students, in Newborn Heel Blood Collection overallStatus: COMPLETED date: 2023-04-01 date: 2023-05-30 date: 2023-05-30 date: 2024-04-18 date: 2024-04-18 name: Celal Bayar Universi... |
<|newrecord|> nctId: NCT06373861 id: 20-0482 briefTitle: Generating Advancements Through Longitudinal Analysis in X and Y Variations (GALAXY) acronym: GALAXY overallStatus: RECRUITING date: 2022-04-28 date: 2037-04 date: 2037-04 date: 2024-04-18 date: 2024-04-18 name: University of Colorado, Denver class: OTHER name: C... |
<|newrecord|> nctId: NCT06373848 id: 346 briefTitle: Comparison of Salivary Parameters in Patients Receiving CoQ10 and Vitamin E Supplementation overallStatus: ENROLLING_BY_INVITATION date: 2024-04-20 date: 2024-08-20 date: 2024-09-15 date: 2024-04-18 date: 2024-04-18 name: Islamic Azad University, Tehran class: OTHER ... |
<|newrecord|> nctId: NCT06373835 id: EMODEPSIDE_LAOS briefTitle: Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-07-31 date: 2024-07-31 date: 2024-04-18 date: 2024-04-18 name: Swiss Tropical & Public Health Institute cl... |
<|newrecord|> nctId: NCT06373822 id: 2024/18JAN/028 briefTitle: New Perspectives in Adenomyosis Pathogenesis With Epigenetic Analysis and miRNAs acronym: ADENO-MIRNA overallStatus: RECRUITING date: 2024-03-21 date: 2031-09 date: 2031-09 date: 2024-04-18 date: 2024-04-22 name: Université Catholique de Louvain class: OTH... |
To identify differentially expressed miRNAs in the blood of adenomyosis patients in view to develop new diagnostic methods |
Hypotheses Circulating miRNAs may be abnormally expressed in patients suffering from adenomyosis and could be used to diagnose the disease |
Study Design Blood samples will be collected from healthy subjects and adenomyosis patients and miRNAs will be isolated and analyzed to detect potential differences. conditions: Adenomyosis studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 50 type: ESTIMATED name: Circula... |
<|newrecord|> nctId: NCT06373809 id: PDSC1970222 briefTitle: Placenta Derived Stem Cells for Treating of Chronic Ulcers and Neuropathy acronym: PDSC overallStatus: COMPLETED date: 2021-10-08 date: 2024-03-31 date: 2024-03-31 date: 2024-04-18 date: 2024-04-18 name: Michael H Carstens class: OTHER name: Ministerio de Sal... |
<|newrecord|> nctId: NCT06373796 id: 2024-A00523-44 briefTitle: Ultrasound Index Fat Fraction acronym: FAT-PLUS overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-07 date: 2024-09 date: 2024-04-18 date: 2024-04-18 name: SuperSonic Imagine class: INDUSTRY briefSummary: The objective is to compare the ultrasound ... |
<|newrecord|> nctId: NCT06373783 id: 2023/05 briefTitle: Ultrasonographic Evaluation of the Connective Tissue Grafts Obtained With Two Different Methods in Root Coverage overallStatus: COMPLETED date: 2023-06-15 date: 2024-01-15 date: 2024-03-16 date: 2024-04-18 date: 2024-04-23 name: Pamukkale University class: OTHER ... |
Coronally advanced flap (CAF) or tunnel technique (TUN) with subepithelial connective tissue procedures have been reported to be the most predictable methods of single gingival recession treatments. The ultimate goal of these plastic periodontal surgical procedures is to close the exposed root surface and achieve optim... |
De-epithelialization of free gingival grafts (DGG) has been proposed, especially when palatal tissue thickness is insufficient (≤2.5 mm) and larger graft size in the apico-coronal or mesio-distal directions is required. In this technique, the graft of the required width and length is separated from the lateral side of ... |
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