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The first trial in the series will compare a research dissemination tool (infographic) against a plain-language summary comparator. Participants will be randomly assigned to receive the dissemination tool or comparator. Study participants will rate communication tools for (1) information completeness; (2) understandabi... |
<|newrecord|> nctId: NCT06373250 id: sdilek7 briefTitle: Maternal Consequences of Membrane Stripping overallStatus: RECRUITING date: 2024-04-11 date: 2024-10-11 date: 2024-11-11 date: 2024-04-18 date: 2024-04-18 name: Kocaeli University class: OTHER briefSummary: This study aims to investigate the maternal effects of m... |
<|newrecord|> nctId: NCT06373237 id: INC-IG-2024-001 briefTitle: Outcome of Embryos Transferred After Initial Chaotic Results on PGT-A overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-26 date: 2024-05 date: 2026-05 date: 2024-04-18 date: 2024-04-18 name: Inception Fertility, LLC class: INDUSTRY name: Igenomix briefSu... |
<|newrecord|> nctId: NCT06373224 id: 23-037 briefTitle: Cold Saline Irrigation Before Endobronchial Biopsy overallStatus: RECRUITING date: 2023-12-01 date: 2024-12-02 date: 2025-02-02 date: 2024-04-18 date: 2024-04-22 name: TriHealth Inc. class: OTHER briefSummary: Patients undergoing an endobronchial ultrasound and bi... |
<|newrecord|> nctId: NCT06373211 id: APHP230701 id: 2023-506942-22-01 type: OTHER domain: CTIS briefTitle: Early Immunotherapy With Intravenous Immunoglobulin, Cyclophosphamide and Methylprednisolone in Patients With Anti-Hu-associated Paraneoplastic Sensory Neuronopathy acronym: NESPA overallStatus: NOT_YET_RECRUITING... |
<|newrecord|> nctId: NCT06373198 id: 0040/2023-versión 1.0 briefTitle: Implementation of a Re-engagement Program for Hepatitis C Patients Lost to Follow-up in Argentina. overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-07-01 date: 2025-01-15 date: 2024-04-18 date: 2024-04-18 name: Hospital El Cruce class: ... |
From a public health perspective, HCV prevalence will be eliminated if the available treatment also targets those most likely to transmit the virus. Despite this scientific advance, a systematic review from the U.S. described that of the 43% of patients aware of their HCV diagnosis, only 16% started treatment. Clearly,... |
Currently, patient unawareness of HCV infection represents one of the major barriers to treatment. In many cases, the diagnosis of HCV was established many years ago and patients do not seek treatment probably because they do not recognize the urgency of treating this asymptomatic infection. It is our goal, then, to id... |
<|newrecord|> nctId: NCT06373185 id: 2023/21 briefTitle: Comparison of the Efficacy of Sacral Espb and Caudal Block for Pain Management After Urogenital Surgeries in Children acronym: SESPB overallStatus: RECRUITING date: 2024-04-22 date: 2024-05 date: 2024-06 date: 2024-04-18 date: 2024-04-23 name: Giresun University ... |
<|newrecord|> nctId: NCT06373172 id: 202005-HR-003 briefTitle: Enhancing Clinical Reasoning Competency acronym: Reasoning overallStatus: COMPLETED date: 2020-05-01 date: 2020-06-01 date: 2023-03-01 date: 2024-04-18 date: 2024-04-18 name: Tongmyong University class: OTHER briefSummary: Enhancing Clinical Reasoning Compe... |
Aims: Clinical reasoning is a core nursing competency that involves analyzing patient-related data and providing appropriate nursing practices. Simulation-based education is effective in improving the clinical reasoning competencies and communication skills of nursing students. This study aimed to verify the effectiven... |
<|newrecord|> nctId: NCT06373159 id: 22643 briefTitle: An Observational Study to Learn About the Occurrence of Disseminated Intravascular Coagulation Among Adults With Sepsis in Japan overallStatus: ACTIVE_NOT_RECRUITING date: 2024-04-10 date: 2024-09-30 date: 2024-09-30 date: 2024-04-18 date: 2024-04-18 name: Bayer cl... |
In observational studies, only observations are made without participants receiving any advice or changes to their healthcare. |
DIC is a serious blood disorder that can cause clots throughout the body, blocking blood vessels. People who have sepsis or cancer are at a higher risk of developing DIC. |
To find a treatment that works well for people with DIC associated with sepsis, it is important to know about its occurrence, treatments people receive, and their outcomes. Japan is the only country that has officially approved medicines for DIC including a few newer medicines that prevent extensive blood clotting. |
In this study, researchers will assess patient data from a hospital database in Japan. |
The main purpose of this study is to learn more about how many adults develop DIC related to sepsis, thrombocytopenic sepsis (sudden decrease in the number of platelets in the blood), or septic shock (dangerously low blood pressure) in Japan every year. |
To learn about this, researchers will collect the following information: |
* The number of participants who developed DIC 14 days, 21 days and 28 days after their sepsis diagnosis |
* The grading scores given to the participants which are used to assess the likelihood, cause, severity, treatment plan, and outcome of DIC (including scores called JAAM, ISTH, MHLW, and/or SOFA scores) |
* The number of days between diagnosis of sepsis and the beginning of DIC |
Researchers will study the data collected between June 2018 and June 2023. The data will come from TXP Medical, which collects data through the hospital health information system of 7 selected hospitals for this study across Japan. |
In this study, only available data from routine care are collected. conditions: Sepsis conditions: Disseminated Intravascular Coagulation studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 5740 type: ESTIMATED name: No study intervention measure: Incidence of DIC assessed at 14 da... |
<|newrecord|> nctId: NCT06373146 id: 18750 id: I8F-MC-GPIV type: OTHER domain: Eli Lilly and Company briefTitle: A Study of Tirzepatide (LY3298176) Plus Mibavademab Compared With Tirzepatide Alone in Adult Participants With Obesity overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-12 date: 2026-04 date: 2024-0... |
<|newrecord|> nctId: NCT06373133 id: 2024 (82) briefTitle: SHR-8068 Combined With Adbelizumab and BP102 in the Treatment of Advanced Colorectal Cancer overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-11-01 date: 2026-11-01 date: 2024-04-18 date: 2024-04-18 name: West China Hospital class: OTHER briefSummar... |
<|newrecord|> nctId: NCT06373120 id: QX20231057-X-1 briefTitle: Interventional Ventricular Assist System for PCI in CHIP Patients acronym: REC-CHIPMCS overallStatus: RECRUITING date: 2024-03-01 date: 2025-03-30 date: 2025-04-30 date: 2024-04-18 date: 2024-04-18 name: Xijing Hospital class: OTHER briefSummary: In patien... |
During CHIP, hemodynamics can deteriorate because of temporary complete coronary occlusion or profound myocardial ischemia. This could result in loss of cardiac output and hemodynamics collapse. Mechanical support during CHIP facilitates native cardiac function by achieving a stable hemodynamic state to withstand repet... |
There are several mechanical circulatory support (MCS) systems available, i.e., intra-aortic balloon counterpulsation (IABP), Impella, TandemHeart, and veno-arterial extracorporeal membrane oxygenation (VA-ECMO). These MCS have been widely studied in patients with acute myocardial infarction (MI) complicated by cardiog... |
The aim of the study is to evaluate the effectiveness of interventional ventricular assist system (CorVad) compared to the venoarterial extracorporeal membrane oxygenation (VA-ECMO) system in providing circulatory support for complicated and high-risk patient with indications for PCI. conditions: High-Risk Percutaneous... |
<|newrecord|> nctId: NCT06373107 id: 2117651-2 briefTitle: Investigating Effects of High-intensity Gait Training on Gait, Balance and Depression Post-stroke overallStatus: NOT_YET_RECRUITING date: 2024-04-11 date: 2025-10-30 date: 2026-01-31 date: 2024-04-18 date: 2024-04-18 name: Alvernia University class: OTHER name:... |
<|newrecord|> nctId: NCT06373094 id: DON102-CTP briefTitle: A Single Dose Escalation Study of HHT201 in Healthy Subjects overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-03-31 date: 2025-03-31 date: 2024-04-18 date: 2024-04-18 name: Shanghai Synergy Pharmaceutical Sciences Co., Ltd. class: INDUSTRY briefSu... |
<|newrecord|> nctId: NCT06373081 id: CD19-CD3E-CN-A1 briefTitle: Anti-CD19-CD3E-CAR-T Cells in Relapsed/Refractory Autoimmune Disease overallStatus: RECRUITING date: 2024-04-20 date: 2025-04-15 date: 2026-04-15 date: 2024-04-18 date: 2024-04-18 name: Shanghai Changzheng Hospital class: OTHER briefSummary: This is an in... |
<|newrecord|> nctId: NCT06373068 id: Resuscitation Orders ICU briefTitle: Association Between Resuscitation Orders and Mortality in ICU Patients overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-12 date: 2025-03 date: 2024-04-18 date: 2024-04-24 name: Karolinska Institutet class: OTHER briefSummary: The hypoth... |
<|newrecord|> nctId: NCT06373055 id: 4-2023-1232 briefTitle: Prediction of Therapeutic Response to Neoadjuvant Chemotherapy in Muscle Invasive Bladder Cancer Patients Using Spatial Transcriptomics overallStatus: RECRUITING date: 2024-05-01 date: 2033-11 date: 2033-11 date: 2024-04-18 date: 2024-04-18 name: Yonsei Unive... |
<|newrecord|> nctId: NCT06373042 id: ADJUVANT-2 briefTitle: Tirofiban for Successful Endovascular Stroke Thrombectomy acronym: ADJUVANT-2 overallStatus: NOT_YET_RECRUITING date: 2024-07-31 date: 2026-07-31 date: 2026-10-31 date: 2024-04-18 date: 2024-04-18 name: Zhongming Qiu class: OTHER name: The Second Affiliated Ho... |
Mechanical thrombectomy mainly addressed the occluded large arteries, and does not consider the distal arteries. However, the recanalization of occluded large arteries does not necessarily translate into successful reperfusion of the ischemic tissue supplied by the distal capillaries. Even with complete recanalization,... |
Whether early administration of intraarterial and intravenous tirofiban can further improve the clinical outcomes of patients with large vessel occlusive stroke after successful mechanical thrombectomy remains unclear. conditions: Stroke, Acute Ischemic studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation... |
<|newrecord|> nctId: NCT06373029 id: 2023PHB211-001(2) briefTitle: Deep-learning Enabled Ultrasound Diagnosis of Anterior Talofibular Ligament Injury overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2024-05-30 date: 2025-12-30 date: 2024-04-18 date: 2024-04-18 name: Peking University People's Hospital class: OT... |
<|newrecord|> nctId: NCT06373016 id: 2015P000652 id: 2023005 type: OTHER_GRANT domain: Baszucki Foundation briefTitle: Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder overallStatus: RECRUITING date: 2024-01-26 date: 2027-02-01 date: 2027-02-01 date: 2024-04-18 date: 2024-04-18 name: Stony Brook Univ... |
<|newrecord|> nctId: NCT06373003 id: SNAPSITA briefTitle: Negative Antiphospholipid Syndrome: a Multicentric Study acronym: SNAPSITA overallStatus: RECRUITING date: 2024-03-31 date: 2026-03-31 date: 2026-03-31 date: 2024-04-18 date: 2024-04-18 name: Italian Society for Rheumatology class: OTHER briefSummary: Multicentr... |
The main objective of the study is to assess the diagnostic accuracy of non-criteria aPL (anti-vimentin/cardiolipin and anti-phosphatidylserine/prothrombin) in identifying APS in patients with thrombosis/recurrent adverse pregnancy outcomes. |
The recruited patients have the following criteria: |
(i)Patients fulfilling the classification criteria for antiphospholipid syndrome (seropositive APS, SP-APS) or patients with seronegative APS (SN-APS) or patients with clinical criteria (thrombotic or obstetric) for APS, negative for aPL, but without clinical features highly suggestive of APS; (ii) Age \<65 years; (iii... |
<|newrecord|> nctId: NCT06372990 id: 0015338 briefTitle: Rapid T-cell Analysis Test in Patients With Chronic HBV and HBV/HDV Disease acronym: BDTc overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-09-30 date: 2026-09-30 date: 2024-04-18 date: 2024-04-18 name: Fondazione IRCCS Ca' Granda, Ospedale Maggiore P... |
The study design allows longitudinal evaluation of the immune response during the natural history of the infection and/or treatment, correlating the data with the outcome of the disease and antiviral therapies, which will be collected as study variables from the source documents. |
The study population will be patients suffering from chronic HBV infection with or without HBV-HDV co-infection followed at the Division of Gastroenterology and Hepatology of Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico. |
The present study is part of an international cooperation project between the Division of Gastroenterology and Hepatology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (Milan, Italy) and the Duke-NUS Medical School, Singapore, financed by a grant (project MAECI-2023-23683653) and divided into two specific ... |
* WP 1 Milan team (WP1.1 - Clinical and virological phenotyping of CHB and CHD patients; WP1.2 - Clinical evaluation of rapid HBV T cell test in CHB and CHD populations) |
* WP 2 Singapore team (WP2.1 - Applicability of the rapid T cell assay approach; WP 2.2 - Optimization of the rapid T cell assay protocol) |
The primary objective of the study is to define the prevalence of specific T cell responses in patients with chronic HBV and HBV-HDV infection, through the application of a specific rapid T cell assay. conditions: HBV conditions: HBV/HDV studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE c... |
<|newrecord|> nctId: NCT06372977 id: kappa index in ms briefTitle: Kappa Index Versus Csf Oligoclonal Bands in Diagnosis of ms and Prediction of Disease Activity overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-12 date: 2026-05 date: 2024-04-18 date: 2024-04-18 name: Assiut University class: OTHER briefSummar... |
1. Compare the diagnostic performance of cerebrospinal fluid kappa index to that of cerebrospinal fluid IgG oligoclonal bands in differentiating multiple sclerosis from other inflammatory and non-inflammatory neurological diseases . |
2. Assess the role of kappa free light chain and oligoclonal bands in predicting disease activity (conversion from clinical isolated syndrome to multiple sclerosis) conditions: Multiple Sclerosis studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: CROSS_SECTIONAL count: 140 type: ESTIMATED name: ... |
<|newrecord|> nctId: NCT06372964 id: ITI-007-421 briefTitle: Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients overallStatus: RECRUITING date: 2024-04 date: 2027-04 date: 2027-05 date: 2024-04-18 date: 2024-04-23 name: Intra-Cellular Therapies, Inc. class: INDUSTRY briefSum... |
<|newrecord|> nctId: NCT06372951 id: Lung ultrasound in neonate briefTitle: Lung Ultrasound in Neonatal Intensive Care Units overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-03 date: 2026-03 date: 2024-04-18 date: 2024-04-18 name: Assiut University class: OTHER briefSummary: Identification of lung diseases... |
<|newrecord|> nctId: NCT06372938 id: AEŞH-BADEK-2024-43 briefTitle: Role of Inflammatory Markers and Doppler Parameters in Late-Onset Fetal Growth Restriction: A Machine Learning Approach overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-31 date: 2024-04-30 date: 2024-04-30 date: 2024-04-18 date: 2024-04-18 name: Anka... |
<|newrecord|> nctId: NCT06372925 id: CKJX839A1CN04 id: CKJX839A1CN04 type: OTHER domain: Novartis briefTitle: Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction acronym: V-ACCELERATE overallStatus: NOT_YET_RECRUITING date: 2024-07-23 date: 2026-06-24 date: 202... |
<|newrecord|> nctId: NCT06372912 id: Complications-Bariatric-TJ briefTitle: Early Postoperative Complications in Patients Undergoing Bariatric Surgery overallStatus: RECRUITING date: 2024-04-01 date: 2024-12-31 date: 2024-12-31 date: 2024-04-18 date: 2024-04-18 name: Instituto Mexicano del Seguro Social class: OTHER_GO... |
<|newrecord|> nctId: NCT06372899 id: 855140 id: R01CA290541-01A1 type: NIH link: https://reporter.nih.gov/quickSearch/R01CA290541-01A1 briefTitle: Alternative Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-11 date: ... |
<|newrecord|> nctId: NCT06372886 id: 2402-147-1516 briefTitle: Clinical Outcomes of Preservation Versus Resection of Portal/Superior Mesenteric Vein During Pancreaticoduodenectomy in Pancreatic Cancer Patients Who Respond to Neoadjuvant Treatment overallStatus: COMPLETED date: 2012-01-01 date: 2022-01-01 date: 2024-03-... |
2. There is no significant differences in R0 rate, 5-year overall survival and recurrence-free survival between the PV/SMV preservation (PVP) group and PV/SMV resection (PVR) group. |
3. PVP group showed significantly better 5-year PV/SMV stenosis free survival than the PVR group. |
4. We propose that if dissection is possible and there is a high likelihood of achieving R0 resection after NAT, routine PVR may be unnecessary in PDAC patients with venous involvement. conditions: Pancreatic Head Cancer Patients Who Underwent Surgery After Neoadjuvant Treatment studyType: OBSERVATIONAL observationalMo... |
<|newrecord|> nctId: NCT06372873 id: 2023PHB211-001 briefTitle: Deep-learning For Ultrasound Classification of Anterior Talofibular Ligament Injury overallStatus: ACTIVE_NOT_RECRUITING date: 2024-04-01 date: 2024-04-30 date: 2025-05-30 date: 2024-04-18 date: 2024-04-23 name: Peking University People's Hospital class: O... |
The investigators collected US images of ATFL injuries which had arthroscopic surgery results as reference standard form 13 hospitals across China;Then the investigators divided the images into training dataset, internal validation dataset, and external validation dataset in a ratio of 8:1:1; the investigators chose an... |
<|newrecord|> nctId: NCT06372860 id: RKS2018350 id: 3P20GM144269-02S2 type: NIH link: https://reporter.nih.gov/quickSearch/3P20GM144269-02S2 briefTitle: DPP Feasibility Study of Breastfeeding - eMOMS 2.0 overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-12 date: 2025-02 date: 2024-04-18 date: 2024-04-18 name: ... |
<|newrecord|> nctId: NCT06372847 id: Project ID 6214 briefTitle: DISE-HNS Effect Study acronym: DISE-HNS overallStatus: NOT_YET_RECRUITING date: 2024-04-23 date: 2028-03-31 date: 2028-03-31 date: 2024-04-18 date: 2024-04-18 name: University Hospital, Antwerp class: OTHER briefSummary: The purpose of this study is to as... |
Furthermore, outcomes will be compared between responders and non-responders. conditions: Obstructive Sleep Apnea studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Before-and-after study primaryPurpose: BASIC_SCIENCE masking: NONE count: 58 type: ESTIMATED... |
<|newrecord|> nctId: NCT06372834 id: B202205178 briefTitle: Adjuvant Accelerated piTBS for Reducing Suicidal Ideation in TRD Patients: A Randomized, Sham-controlled Trial overallStatus: RECRUITING date: 2022-11-07 date: 2024-12-31 date: 2024-12-31 date: 2024-04-18 date: 2024-04-18 name: Tri-Service General Hospital cla... |
<|newrecord|> nctId: NCT06372821 id: 158160 briefTitle: A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK acronym: NIO-SILK overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-02 date: 2025-08 date: 2024-04-18 date: 2024-04-18 name: University College, London class: OTH... |
<|newrecord|> nctId: NCT06372808 id: 2022/118 briefTitle: The Effect of Plyometric Training in Freestyle Adolescent Wrestlers overallStatus: RECRUITING date: 2023-10-01 date: 2024-06-18 date: 2024-09-15 date: 2024-04-18 date: 2024-04-19 name: Hasan Kalyoncu University class: OTHER briefSummary: This study aims to deter... |
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