Inuyashiki (いぬやしき) is a Japanese science fiction manga series written and illustrated by Hiroya Oku. It was serialized in Kodansha's seinen manga magazine Evening from January 2014 to July 2017, with its chapters collected in 10 tankōbon volumes. The story follows two people, who via a mysterious event, are endowed with super abilities, but the way they choose to use these abilities is completely different.
 A 11-episode anime television series adaptation produced by MAPPA aired on Fuji TV's late night programming block Noitamina from October to December 2017. A live-action film adaptation premiered in April 2018.
 Inuyashiki Ichiro is an older, friendless man with an uncaring family. One fateful evening in a nearly empty public park, he is struck by an explosion of extraterrestrial origin, and his body is replaced by an incredibly powerful, but still outwardly human, mechanical body. He quickly realizes the extent of his body's powers, and after saving a homeless man being beaten by a pack of teenagers, he decides to dedicate himself to doing good, using his powers to heal those with incurable diseases and fight crime.
 However, a teenager who was with him at the time of the explosion, Shishigami Hiro, had the same fate as Ichiro, but unlike Inuyashiki, Shishigami becomes a psychopath who goes about using his newfound abilities to murder various people, from classmates that annoy him to innocent families, including young children, just for amusement. His acts of merciless cruelty bring him the attention of the police, who can do nothing to stop him. Hiro becomes the most wanted criminal in the country. The series follows these two different people who once shared the same bizarre experience, as their paths are destined to clash.
 Written and illustrated by Hiroya Oku, Inuyashiki was serialized in Kodansha's seinen manga magazine Evening, from January 28, 2014, to July 25, 2017. Kodansha collected its 85 chapters in ten tankōbon volumes, released from May 23, 2014, to September 22, 2017.
 Kodansha USA licensed the manga for English release in North America in 2014. The ten volumes were released from August 25, 2015, to December 19, 2017. Crunchyroll started publishing the manga in a digital format in 2015; the service is set to end in December 2023.
 An anime television series adaptation by MAPPA began airing on October 12, 2017, and a live-action film adaptation has been announced for 2018. The anime series' opening theme is "My Hero", performed by Japanese rock band Man with a Mission. The ending theme "Ai o Oshietekureta Kimi e" (愛を教えてくれた君へ, lit. "To You Who Taught Me Love") is performed by the band Qaijff. Amazon had licensed the series and streamed it online on Amazon Prime Video in Japan and overseas. It was streamed on Anime Strike in the United States. Amazon discontinued Anime Strike on January 5, 2018, which in turn made their titles, including Inuyashiki, free to stream for Prime members. The anime series became available on Crunchyroll on April 26, 2023.
 On December 21, 2017, a teaser trailer and website appeared for a live-action adaptation of Inuyashiki. The film, the first in a planned trilogy, was released on April 20, 2018, directed by Shinsuke Sato, who had previously directed the live-action Gantz, and stars Noritake Kinashi as Inuyashiki Ichihiro and Takeru Satoh as Shishigami Hiro.
 Inuyashiki was one of the Manga division's Jury Selections at the 18th and 19th Japan Media Arts Festival in 2014 and 2015. The manga has won the French award "Daruma d'or manga" at the Japan Expo Awards 2016. It was picked as a nominee for Best Comic for the 44th Angoulême International Comics Festival in 2017. Inuyashiki was nominated for the Best Comic category at the 49th Seiun Awards in 2018. The series ranked 18th in the first Next Manga Award in the print manga category.
 By April 2018, the manga had over 3.1 million copies in circulation. Volume 2 reached the 18th place on the weekly Oricon manga charts and, by November 2, 2014, it had sold 76,886 copies; volume 3 reached the 15th place and, by March 1, 2015, it had sold 74,974 copies.
 In February 2021, it was reported that the series, along with Death Note and Tokyo Ghoul, was banned from distribution on two unspecified websites in Russia.
 At the 2nd Crunchyroll Anime Awards held in 2018, Inuyashiki was nominated for "Best CGI" and the character Hiro Shishigami was nominated for "Villain of the Year".