Ames (/eɪmz/) is a city in Story County, Iowa, United States, located approximately 30 miles (48 km) north of Des Moines in central Iowa. It is best known as the home of Iowa State University (ISU), with leading agriculture, design, engineering, and veterinary medicine colleges. A United States Department of Energy national laboratory, Ames Laboratory, is located on the ISU campus.
 According to the 2020 census, Ames had a population of 66,427, making it the state's ninth most populous city. Iowa State University was home to 27,854 students as of spring 2023, which make up approximately one half of the city's population.
 Ames also hosts United States Department of Agriculture (USDA) sites: the largest federal animal disease center in the United States, the USDA Agricultural Research Service's National Animal Disease Center (NADC), as well as one of two national USDA sites for the Animal and Plant Health Inspection Service (APHIS), which comprises the National Veterinary Services Laboratory and the Center for Veterinary Biologics. Ames also hosts the headquarters of the Iowa Department of Transportation.
 The city was founded in 1864 as a station stop on the Cedar Rapids and Missouri Railroad and was named after 19th century U.S. Congressman Oakes Ames of Massachusetts, who was influential in the building of the transcontinental railroad. Ames was founded by local resident Cynthia Olive Duff (née Kellogg) and railroad magnate John Insley Blair, near a location that was deemed favorable for a railroad crossing of the Skunk River.
 Ames is located along the western edge of Story County, roughly 30 miles (48 km) north of the state capital, Des Moines, near the intersection of Interstate 35 and U.S. Route 30. A smaller highway, U.S. Route 69, passes through the town. Also passing through Ames is the cross country line of the Union Pacific Railroad and two small streams (the South Skunk River and Ioway Creek).
 According to the United States Census Bureau, the city has a total area of 24.27 square miles (62.86 km2), of which 24.21 square miles (62.70 km2) is land and 0.06 square miles (0.16 km2) is water.
 
Campustown is the neighborhood directly south of Iowa State University Central Campus bordered by Lincoln Way on the north. Campustown is a high-density mixed-use neighborhood that is home to many student apartments, nightlife venues, restaurants, and numerous other establishments, most of which are unique to Ames. Ames has a humid continental climate (Köppen climate classification Dfa). On average, the warmest month is July and the coldest is January. The highest recorded temperature was 102 °F (39 °C) on July 24, 1901, and the lowest was −37 °F (−38 °C) January 25, 1894.
 As of the census of 2010, there were 58,965 people, 22,759 households, and 9,959 families residing in the city. The population density was 2,435.6 inhabitants per square mile (940.4/km2). There were 23,876 housing units at an average density of 986.2 per square mile (380.8/km2). The racial makeup of the city was 84.5% White, 3.4% African American, 0.2% Native American, 8.8% Asian, 1.1% from other races, and 2.0% from two or more races. Hispanic or Latino of any race were 3.4% of the population.
 There were 22,759 households, of which 19.1% had children under the age of 18 living with them, 35.6% were married couples living together, 5.4% had a female householder with no husband present, 2.7% had a male householder with no wife present, and 56.2% were non-families. 30.5% of all households were made up of individuals, and 6.2% had someone living alone who was 65 years of age or older. The average household size was 2.25 and the average family size was 2.82.
 The median age in the city was 23.8 years. 13.4% of residents were under the age of 18; 40.5% were between the ages of 18 and 24; 22.9% were from 25 to 44; 15% were from 45 to 64; and 8.1% were 65 years of age or older. The gender makeup of the city was 53.0% male and 47.0% female.
 As of the census of 2000, there were 50,731 people, 18,085 households, and 8,970 families residing in the city. The population density was 2,352.3 inhabitants per square mile (908.2/km2). There were 18,757 housing units at an average density of 869.7 per square mile (335.8/km2). The racial makeup of the city was 87.34% White, 7.70% Asian, 2.65% African American, 0.04% Native American, 0.76% Pacific Islander and other races, and 1.36% from two or more races. Hispanic or Latino of any race were 1.98% of the population.
 There were 18,085 households, out of which 22.3% had children under the age of 18 living with them, 42.0% were married couples living together, 5.3% had a female householder with no husband present, and 50.4% were non-families. 28.5% of all households were made up of individuals, and 5.9% had someone living alone who was 65 years of age or older. The average household size was 2.30 and the average family size was 2.85.
 Age spread: 14.6% under the age of 18, 40.0% from 18 to 24, 23.7% from 25 to 44, 13.9% from 45 to 64, and 7.7% who were 65 years of age or older. The median age was 24 years. For every 100 females, there were 109.3 males. For every 100 females age 18 and over, there were 109.9 males.
 The median income for a household in the city was $36,042, and the median income for a family was $56,439. Males had a median income of $37,877 versus $28,198 for females. The per capita income for the city was $18,881. About 7.6% of families and 20.4% of the population were below the poverty line, including 9.2% of those under age 18 and 4.1% of those age 65 or over.
 The U.S. Census Bureau designates the Ames MSA as encompassing all of Story County. While Ames is the largest city in Story County, the county seat is in the nearby city of Nevada, 8 miles (13 km) east of Ames.
 Ames metropolitan statistical area combined with the Boone, Iowa micropolitan statistical area (Boone County, Iowa) make up the larger Ames-Boone combined statistical area. Ames is the larger principal city of the Combined Statistical Area that includes all of Story County, Iowa and Boone County, Iowa. which had a combined population of 106,205 at the 2000 census.
 Ames is home of Iowa State University of Science and Technology, a public land-grant and space-grant research university. At its founding in 1858, Iowa State was known as the Iowa State College of Agriculture and Mechanic Arts. Ames is the home of the closely allied U.S. Department of Agriculture's National Animal Disease Center (See Ames strain), the U.S. Department of Energy's Ames Laboratory (a major materials research and development facility), and the main offices of the Iowa Department of Transportation. State and Federal institutions are the largest employers in Ames.
 Other area employers include a 3M manufacturing plant; Danfoss Power Solutions, a hydraulics manufacturer; Barilla, a pasta manufacturer; Ball, a manufacturer of canning jars and plastic bottles; Workiva, a global cloud computing company; Renewable Energy Group, America's largest producer of biomass-based diesel; and the National Farmers Organization.
 The Iowa State University Research Park is a not-for-profit business development incubator located in Ames, and affiliated with Iowa State University.
 In 2015, Ames was ranked in the top 15 "Cities That Have Done the Best Since the Recession" by Bloomberg Businessweek.
 The Bureau of Labor Statistics ranked Ames and Boulder, Colorado as having the lowest unemployment rate (2.5%) of any metropolitan area in the US in 2016. By June 2018, unemployment in Ames had fallen even further, to 1.5%, though wage increases for workers were not keeping pace with rising rents.
 As of 2022, the top employers in the city are:
 of Total City
Employment
 The Iowa State Cyclones play a variety of sports in the Ames area. The Iowa State Cyclones football team plays at Jack Trice Stadium in Ames. Also, the Cyclones' Men's and Women's Basketball teams and Volleyball teams play at Hilton Coliseum just across the street from Jack Trice Stadium. The Iowa State Cyclones are a charter member of the Big 12 Conference in all sports and compete in NCAA Division I-A. The Iowa State Women's Tennis is also well known and very successful.
 The Ames Figure Skating Club provides recreational to professional level skating opportunities.  The club sponsors the Learn to Skate Program.  Coaches provide on and off ice lessons or workshops. The club hosts the figure skating portion of the Iowa Games competition every summer.  In the fall the club hosts Cyclone Country Championships.
 The Ames ISU ice arena also hosts the Iowa State Cyclones hockey team. The arena also hosts the Ames Little Cyclones hockey program for high school students and children in elementary or middle school.
 Much of the city is served by the Ames Community School District.
 A portion of northern Ames is zoned to the Gilbert Community School District.
 Ames High School: Grades 9–12
 Gilbert CSD students are zoned to Gilbert High School.
 Iowa State University of Science and Technology, more commonly known as Iowa State University (ISU), is a public land-grant and space-grant research university located in Ames. Iowa State University is the birthplace of the Atanasoff–Berry Computer, the world's first electronic digital computer. Iowa State has produced a number of astronauts, scientists, Nobel laureates, and Pulitzer Prize winners. Until 1945 it was known as the Iowa State College of Agriculture and Mechanic Arts. The university is a member of the American Association of Universities and the Big 12 Conference.
 
 ISU is the nation's first designated land-grant university. In 1856, the Iowa General Assembly enacted legislation to establish the State Agricultural College and Model Farm. Story County was chosen as the location on June 21, 1859, from proposals by Johnson, Kossuth, Marshall, Polk, and Story counties. When Iowa accepted the provisions of the Morrill Act of 1862, Iowa State became the first institution in nation designated as a land-grant college. The institution was coeducational from the first preparatory class admitted in 1868. The formal admitting of students began the following year, and the first graduating class of 1872 consisted of 24 men and 2 women.
 The first building on the Iowa State campus was Farm House. Built in the 1860s, it currently serves as a museum and National Historic Landmark. Today, Iowa State has over 60 notable buildings, including Beardshear Hall, Morrill Hall, Memorial Union, Catt Hall, Curtiss Hall, Carver Hall, Parks Library, the Campanile, Hilton Coliseum, C.Y. Stephens Auditorium, Fisher Theater, Jack Trice Stadium, Lied Recreation Center, numerous residence halls, and many buildings specific to ISU's many different majors and colleges.
 The official mascot for ISU is Cy the Cardinal. The official school colors are cardinal and gold. The Iowa State Cyclones play in the NCAA's Division I-A as a member of the Big 12 Conference.
 Ames is also served by stations in the Des Moines media market, which includes Clear Channel's 50,000-watt talk station WHO, music stations KAZR, KDRB, KGGO, KKDM, KHKI, KIOA, KJJY, KRNT, KSPZ and KSTZ, talk station KWQW, and sports stations KXNO and KXNO-FM.
 Like radio, Ames is served by the Des Moines media market. WOI-DT, the ABC affiliate in central Iowa, was originally owned and operated by Iowa State University until the 1990s. The station is still licensed to Ames, but studio's are located in West Des Moines. Other stations serving Ames include KCCI, KDIN-TV, WHO-DT, KCWI-TV, KDMI, KDSM-TV and KFPX-TV.
 Channel 12 is owned by the City of Ames and overseen by the City Manager's Office. The channel broadcasts meetings for city council as well as other city government councils and boards. Channel 12 also produces its own original content focused on news and other happenings in Ames. Channel 12 has won various regional and national awards including a NATOA Government Programming Award and a Telly Award. Channel 12's goals are "To provide quality programming to the citizens of Ames that educates and informs about city government issues" and "To provide live coverage and rebroadcasts of council and commission meetings."
 Channel 16 serves as Ames' public access TV channel. "The purpose of Ames Public Access TV (Channel 16) is to provide residents the opportunity to broadcast locally produced programs on cable television.  APATV provides cablecasting of non-commercial, public access programming independently produced by professionals or non-professionals in either a VHS or DVD format.  This service is provided on a first-come-first-served, non-discriminatory, non monopolistic basis.  Other services include video messaging to serve as a community calendar."
 The town is served by U.S. Highways 30 and 69 and Interstate 35. Ames is the only town in Iowa with a population of greater than 50,000 that does not have a state highway serving it. As of 2019, Ames currently has three roundabouts constructed on University Avenue/530th Avenue. The first is at the intersection of Airport Road (Oakwood Rd.) and University Avenue, the second at the intersection of Cottonwood Road and 530th Avenue and the third at Collaboration Place and 530th Avenue.
 Ames was serviced by the Fort Dodge, Des Moines and Southern Railroad via a branch from Kelley to Iowa State and to downtown Ames. The tracks were removed in the 1960s. The Chicago and North Western Transportation Company twin mainline runs east and west bisecting the town and running just south of the downtown business district. The C&NW used to operate a branch to Des Moines. This line was removed in the 1980s when the Spine Line through the nearby city of Nevada was purchased from the Rock Island Railroad after its bankruptcy. The Union Pacific, successor to the C&NW, still runs 60–70 trains a day through Ames on twin mainlines, which leads to some traffic delays. There is also a branch to Eagle Grove that leaves Ames to the north. The Union Pacific maintains a small yard called Ames Yard east of Ames between Ames and Nevada. Ames has been testing automatic train horns at several of its crossings. These directional horns which are focused down the streets are activated when the crossing signals turn on and are shut off after the train crosses the crossing. This system cancels out the need for the trains to blow their horns. Train noise had been a problem in the residential areas to the west and northwest of downtown.
 Ames Municipal Airport is located 1 mile (1.6 km) southeast of the city. The current (and only) fixed-base operator is Central Iowa Air Service. The airport has two runways – 01/19, which is 5,700 by 100 feet (1,737 m × 30 m), and 13/31, which is 3,492 by 100 feet (1,064 m × 30 m).
 The City of Ames offers a transit system throughout town, called CyRide, that is funded jointly by Iowa State University, the ISU Government of the Student Body, and the City of Ames. Rider fares are free for children under five, while students pay a set cost as part of their tuition. In addition to local transit, Ames is served by intercity buses from Jefferson Lines, which stop at the Ames Intermodal Facility.
 In 2009, the Ames metropolitan statistical area (MSA) ranked as the third highest in the United States for percentage of commuters who walked to work (10.4 percent).
 The City of Ames unveiled a potential bike plan at an open house on November 15, 2023, as part of the city's Walk Bike Roll Bicycle and Pedestrian project. The project has been in development since summer 2022. Particular recommendations from the project include improvements being made to Clark Avenue, Lincoln Highway, Grand Avenue and Duff Street in Ames.
 Ames is home to the headquarters of the Iowa Department of Transportation.
 Ames is served by Mary Greeley Medical Center, a 220-bed regional referral hospital which is adjacent to McFarland Clinic PC, central Iowa's largest physician-owned multi-specialty clinic, and also Iowa Heart Center.
 On September 10, 2019 the City of Ames proposed a $29,000,000 bond for building a fitness center called the Healthy Life Center. It failed to pass. Iowa State University owns the land it was to be built on.
 This is a list of notable people associated with Ames, Iowa arranged by career and in alphabetical order. For people associated with Iowa State University not originally from Ames, including athletes and employees of the school, see List of Iowa State University alumni
 From 1979 through 2011, Ames was the location of the Ames Straw Poll, which was held every August prior to a presidential election year in which the Republican presidential nomination was undecided (meaning there was no Republican president running for re-election—as in 2011, 2007, 1999, 1995, 1987, and 1979). The poll would gauge support for the various Republican candidates amongst attendees of a fundraising dinner benefiting the Iowa Republican Party. The straw poll was frequently seen by national media and party insiders as a first test of organizational strength in Iowa. In 2015, the straw poll was to be moved to nearby Boone before the Iowa Republican Party eventually decided to cancel it altogether.