Cherry County is a county located in the U.S. state of Nebraska. As of the 2020 United States Census, the population was 5,455. Its county seat is Valentine. The county was named for Lt. Samuel A. Cherry, an Army officer who was stationed at Fort Niobrara and who had been killed in South Dakota in 1881. Cherry County is in the Nebraska Sandhills. It is the largest county in the state at nearly 6,000 square miles (16,000 km2), larger than the state of Connecticut.
 In the Nebraska license plate system, Cherry County is represented by the prefix 66 (it had the 66th-largest number of vehicles registered in the state when the license plate system was established in 1922).
 Cherry County lies on the north side of Nebraska. Its north boundary line abuts the south boundary line of the state of South Dakota. According to the US Census Bureau, the county has an area of 6,009 square miles (15,560 km2), of which 5,960 square miles (15,400 km2) is land and 49 square miles (130 km2) (0.8%) is water. It is by far Nebraska's largest county in land area and larger than the state of Connecticut, or the states of Delaware and Rhode Island combined. The county is in Nebraska's Sandhills region; the dunes that give the region its name are a result of the most recent glacial period, the Pinedale glaciation. During the Holocene glacial retreat the sand dunes, which had been deposited in their current location by the vast continental glaciers, were exposed and grasses eventually took over.
 Owing to its size as Nebraska's largest county by area, Cherry County borders 11 counties, more than any other county in Nebraska. Seven of them are in Nebraska and four are in South Dakota. The adjacent counties are:
 As of the 2000 United States Census, of 2000, there were 6,148 people, 2,508 households, and 1,710 families in the county. The population density was 1.02 people per square mile (0.39 people/km2). There were 3,220 housing units at an average density of 0 units per square mile (0/km2). The racial makeup of the county was 94.19% White, 0.07% Black or African American, 3.25% Native American, 0.42% Asian, 0.02% Pacific Islander, 0.33% from other races, and 1.72% from two or more races. 0.93% of the population were Hispanic or Latino of any race. 38.5% were of German, 12.6% English, 11.1% Irish and 7.3% American ancestry.
 There were 2,508 households, out of which 31.70% had children under the age of 18 living with them, 57.90% were married couples living together, 6.90% had a female householder with no husband present, and 31.80% were non-families. 28.90% of all households were made up of individuals, and 12.70% had someone living alone who was 65 years of age or older. The average household size was 2.42 and the average family size was 2.98.
 The county population contained 27.00% under the age of 18, 6.20% from 18 to 24, 25.50% from 25 to 44, 24.00% from 45 to 64, and 17.30% who were 65 years of age or older. The median age was 39 years. For every 100 females there were 98.80 males. For every 100 females age 18 and over, there were 93.60 males.
 The median income for a household in the county was $29,268, and the median income for a family was $36,500. Males had a median income of $23,705 versus $17,277 for females. The per capita income for the county was $15,943. About 9.60% of families and 12.30% of the population were below the poverty line, including 13.40% of those under age 18 and 14.20% of those age 65 or over.
 Cherry County residents observe two zones, the Central and Mountain time zones. The eastern third of the county, including county seat Valentine, is in the Central Time Zone, while the western two thirds, including Merriman, are in the Mountain Time Zone.
 Cherry County voters are reliably Republican. The county has not voted for a Democrat in a presidential election since Franklin D. Roosevelt's 1936 landslide, and even then, the county was decided by less than four points. Republicans have carried the county by a double-digit margin in every election since, and no Democrat since Harry S. Truman in 1948 has even mustered 40% of the vote. Republicans also hold a massive advantage in voter registration in Cherry County, with 2,947 registered Republicans, as opposed to just 325 registered Democrats.
 42°32′N 101°07′W﻿ / ﻿42.54°N 101.12°W﻿ / 42.54; -101.12