Mawlamyine (also spelled Mawlamyaing; Burmese: မော်လမြိုင်မြို့; MLCTS: mau la. mruing mrui., Burmese pronunciation: [mɔ̀ləmjàɪ̯ɰ̃ mjo̰]; Thai: เมาะลำเลิง ; Mon: မတ်မလီု, Mon pronunciation: [mo̤t məlɜ̤m]), formerly Moulmein, is the fourth-largest city in Myanmar (Burma), 300 kilometres (190 mi) south east of Yangon and 70 kilometres (43 mi) south of Thaton, at the mouth of Thanlwin (Salween) River. Mawlamyine was an ancient city and the first capital of British Burma. The city is currently the capital and largest city of Mon State and the main trading centre and seaport in south eastern Myanmar.
 The Mon name which was previously used for Mawlamyine, Moulmein (မတ်မလီု; [mòt məlɜ̀m]) means "damaged eye" or "one-eyed man." According to legend, a Mon king had a powerful third eye in the centre of his forehead, able to see what was happening in neighbouring kingdoms. The daughter of one of the neighbouring kings was given in marriage to the three-eyed king and managed to destroy the third eye. The Burmese name "Mawlamyine" is believed to be a corruption of the Mon name.
 Moulmein was also spelled as Maulmain or Moulmain or Maulmein in some records of the 19th century. The people of Moulmein were referred as Moulmeinian.
 According to Kalyani Inscriptions erected by King Dhammazedi of Hanthawaddy Pegu in 1479, Mawlamyine was mentioned among the ‘32 myo’ or thirty-two Mon cities within the Martaban division. Binnya U, a deputy of Viceroy Saw Binnya, was one of the notable governors of Mawlamyine in the early history of the city.
 In May 1541, King Tabinshwehti and his deputy Bayinnaung captured Mawlamyine. During the reign of Bayinnaung, Toungoo Empire became the largest empire in the history of Southeast Asia. After his passing in 1581, his son Nanda Bayin and successors faced with rebellion by Lan Na, Siam, Lan Xang and renewed Portuguese incursions. In 1594, the governor of Mawlamyine who being in league with Siamese King Naresuan revolted against Toungoo court. Since then, the city became under the control of Siam (present-day Thailand) until 1614.
 In 1760, General Minkhaung Nawrahta of the Royal Burmese Army repaired Mawlamyine on his way back from Burmese–Siamese War in Ayutthaya (former capital of Thailand). Kyaikthanlan Pagoda Inscription hinted that in 1764 (1125 ME), General Maha Nawrahta repaired Kyaikthanlan Pagoda on his way to capture Tavoy, and before finishing the repairment, Mawlamyine faced utter destruction.
 Mawlamyine was the first capital of British Burma between 1826 and 1852 after the Tanintharyi (Tenassarim) coast, along with Arakan, was ceded to Britain under the Treaty of Yandabo at the end of the First Anglo-Burmese War. After the first Anglo-Burmese war, the British made it their capital between 1826 and 1852, building government offices, churches and a massive prison. They started business enterprises and the country's first newspaper, The Maulmain Chronicle. Between 1826 and 1862, colonial Mawlamyine was the center of British Burma and the first port city that became a strategically important area and a geographical nodal point for the newly occupied British territory in Southeast Asia. Ever since the first British occupation in 1824, the growth and prosperity of Mawlamyine had steadily increased due to timber trade. Nevertheless, the decline in prosperity of Mawlamyine began when the supply of marketable timber from Salween Valley started to decrease in the 1890s.
 During British colonial times, Germany, Siam, Persia, Denmark, Norway and Sweden opened and maintained consulates in Mawlamyine led by either consuls or vice-consuls while Italy and the United States placed consular agencies in Mawlamyine. German explorer Johann Wilhelm Helfer's landing at Moulmein shore on 8 February 1837 made him as the first German to arrive Burma in the history.
 Mawlamyine was the setting of George Orwell's famous 1936 memoir Shooting an Elephant. The essay opens with the striking words:
 During colonial times, Moulmein had a substantial Anglo-Burmese population. An area of the city was known as "Little England" due to the large Anglo-Burmese community, many of them running rubber plantations. This has since dwindled to a handful of families as most have left for the UK or Australia.
 It was probably best known to English speakers through the opening lines of Rudyard Kipling's poem Mandalay:
 During WWII, the city and the Tanintharyi Region were the first objectives during the Japanese invasion of Burma.
 The "old Moulmein pagoda" Kipling cites is thought to be the Kyaik Than Lan (also spelled Kyaikthanlan) pagoda in Mawlamyine. It stands on a ridge, giving a panoramic view of the city, and is surrounded by 34 smaller temples. Among its sacred treasures is a hair relic of Buddha, received from a hermit in Thaton, as well as a tooth relic conveyed from Sri Lanka by a delegation of monks in ancient times.
 Soon after Burma's independence in 1948, the city fell into the hands of Karen insurgents. The Myanmar military retook the city with the help of UBS Mayu in 1950. Later, many colonial names of streets and parks of the city were changed to more nationalistic Burmese names. Mawlamyine stood as the third-largest city of Myanmar until the recent rise of Naypyidaw.
 Mawlamyine is in the Salween River delta, where the mouth of the Salween is sheltered by Bilugyun Island as it enters the Gulf of Martaban and the Andaman Sea. It is flanked by low hills dotted with ancient pagodas to the east and west.
 Mawlamyine has a tropical monsoon climate (Köppen: Am) similar to the climates of Dawei and Sittwe. There is a lengthy dry season between mid-November and mid-April, and an extremely wet season due to the southwest monsoon between mid-April and mid-November. Between June and August when the surface westerly winds are strongest and supersaturated air is advected onto the nearby mountains, Mawlamyine averages around 1,100 millimetres or 43 inches of rain per month.
 Mawlamyine Airport has regular flights to Yangon (Rangoon).
 Mawlamyine is the main gateway to south eastern Myanmar. Thanlwin Bridge, the longest road and rail bridge in Myanmar is the most prominent landmark in the area. It stretches 11,000 feet (3,400 metres) over the Thanlwin River connecting the country's south eastern region with Yangon. The city has a central highway bus station. The city is connected to Pa-an in Kayin State in the north-east and Dawei and Myeik in Tanintharyi Division in the south by road. Via Kawkareik, the city is also connected with Thai-Myanmar border town Myawaddy. Newly opened Bogyoke Aung San Bridge (Bilu Kyun) connects Mawlamyine with nearby Bilu island, lies about 500 metres west off the shore of Mawlamyine.
 In Mawlamyine, motorcycles and tuk-tuk (Thone Bee in Burmese) motorized tricycles cumulatively registered for use as taxis. Mawlamyine is also served by bus networks which radiate mostly from the north to the south.
 It was the rail head to Ye, linked to Yangon by rail only from Mottama (Martaban) across the river by ferry, but today connected by the Thanlwin Bridge (Mawlamyine) opened in April 2006.
 Mawlamyine Railway Station, which was reportedly built to the standards of an "ASEAN railway station", is the terminus of Myanmar Railways' Yangon–Mawlamyine Railway and Tanintharyi Line.
 In colonial era, Mawlamyine (then Moulmein) port was served by European shipping companies including Scottish-owned British-India Steam Navigation Company and Irrawaddy Flotilla Company. 
 The port was important not only for inland navigation but also for international shipping. Rice and teak from sawmills at Mawlamyine were exported worldwide by those shipping companies. The 1880 handbook of British-India Steam Navigation Company listed: 
 In 1894, the journey between Barr Street Jetty of Rangoon to the Main Wharf of Moulmein took about nine hours at a fare of 10 Rupees for second class.
 Nowadays, although much diminished from its past prominence, water-based transport still plays an important role in connecting between Mawlamyine and the immediate upstream towns. The Port of Mawlamyine is currently under the management of Myanma Port Authority and is located on the Thanlwin River about 28 nautical miles inland from the Kyaikkhame point on the Gulf of Martaban, 2 kilometers from Mawlamyine railway station.
 Mawlamyine is famous for its tropical fruits and for its cuisine as indicated in the popular Burmese expression, "Mandalay for the speaking, Yangon for the bragging, and Mawlamyine for the eating." (မန္တလေးစကား ရန်ကုန်အကြွား မော်လမြိုင်အစား) Among its tropical fruits, Mawlamyine pomelo, durian and rambutan are traded countrywide.
 Mawlamyine had several sawmills and rice mills as teak and rice were transported down the Salween. It was once a busy shipbuilding center and remains an important port. At least one major British shipping line had some of their ships built here. The teak "country-built" ships generally had a longer service life than those constructed from European hardwoods.  The city had a solar-powered plant for extracting salt from seawater and a diesel electric plant. On the night of 1 December 2008, a fire that started from a floating restaurant destroyed the larger of city's two markets called the lower bazaar.
 The city has two industrial zones. Of two, the newly opened Kyauktan industrial zone features a variety of different business enterprises, including zinc, barbed wire, ready-mix cement, food and drink production, textiles, gold purification, ice factories, shoe production facilities, furniture enterprise, plastic enterprises, cool seafood storage and car accessory businesses.
 As a cross-border investment, the state-of-the-art combined-cycle gas power plant in Mawlamyine was constructed by Singapore's United Overseas Bank (UOB) backed Singapore company Asiatech Energy. The Mawlamyine power plant brings a sustainable supply of power to residents and businesses in Mon State.
 In July 2017, to make the country's oil and gas industry more efficient, the Myanmar Investment Commission (MIC) granted an approval to a subsidiary of Singapore-based firm to construct an offshore supply base in the 46 acres of river front land of Mawlamyine. It would provide a wide range of services to the operators of oil and gas fields in the waters off the coast in the Bay of Bengal.
 Mawlamyine is the western terminus and an important part of the East-West Economic Corridor. The 1450-kilometre east–west economic corridor links the South China Sea at Da Nang to Mawlamyine through Laos and Thailand. By using the East-West Economic Corridor, the travel time between Bangkok and Yangon is just three days, compared with the two to three weeks needed for conventional marine transportation via the Straits of Malacca. Japan's Nippon Express started land transportation services between Thailand and Myanmar in 2016.
 
Mawlamyine provides a multicultural dimension despite a Buddhist Mon majority. Buddhist cultural dominance is as old as Mawlamyine, but the British annexation and American missionaries in the early 19th century introduced Christianity. Many of the relics of the British Raj remain along with Hindu temples, Chinese temples, mosques and even a slice of Americana, reflecting Mawlamyine's great diversity. The First Baptist Church in Mawlamyine was constructed in 1827 by the legendary Adoniram Judson, the first Caucasian Protestant missionary sent from North America to Myanmar. The building is a masterful blend of Western and local elements, with the materials and building technology speaking directly to Mon cultural traditions and crafts expertise. In 2015, the U.S. Embassy in Myanmar announced that it gave an award of $125,000 to World Monuments Fund (WMF) to restore the historic First Baptist Church in Mawlamyine through the Ambassadors Fund for Cultural Preservation.
 The Mon State Cultural Museum exhibits the ancient cultural relics of Mon people and divans used by a Konbaung princess who resided in Mawlamyine.
 Mawlamyine has 13 public high schools, two institutes, a college and three universities.
 The University of Mawlamyine, established in 1953, is the major university for the south eastern region and offers both bachelor's and master's degree programs in liberal arts and sciences. It is the third oldest Arts and Science university in the country after the University of Yangon (est. 1878) and the University of Mandalay (est. 1925). It is one of the few universities in Myanmar that offers a degree in Marine Science. Its Marine Science Laboratory in Setse, a coastal town about 83 km south of Mawlamyine, was the first of its kind in Myanmar. Technological University (Mawlamyine) offers technological and engineering courses. The Mawlamyine campus of Yezin Agricultural University, administered by Ministry of Agriculture, Livestock and Irrigation (MOALI), offers agriculture courses. Government Technical Institute (Mawlamyine) offers vocational engineering courses located in outskirts of the city. Mawlamyine Education College and Mawlamyine Institute of Education are also located in the city.
 The St. Patrick's School (now B.E.H.S. No. 5) founded by the De La Salle Brothers in 1860, Morton Lane-Judson School, (formerly Morton Lane Girls' School, now B.E.H.S No.6) founded in 1867 and Shin Maha Buddhaghosa National School (now B.E.H.S. No.9) founded in 1899 are a few of the oldest public high schools in Myanmar.
 The first international student of Bucknell University, Class of 1864, Maung Shaw Loo was the first Burmese physician of Western medicine and the first Burmese to study Western medicine in the United States.
 The 10,000-seat Yamanya Stadium is one of the main venues for local and regional football tournaments. The stadium is also a home for Southern Myanmar F.C., a Myanmar National League (MNL) football club.
 Mawlamyine established a Friendship City agreement with Fort Wayne, Indiana, United States in 2016. A student exchange program between Mawlamyine University and IPFW of Fort Wayne began in 2017.
 A primary road in Novena, Singapore and a road (Solok Moulmein) in George Town, Malaysia were named after the city's old name, Moulmein.
 16°29′05″N 97°37′33″E﻿ / ﻿16.48472°N 97.62583°E﻿ / 16.48472; 97.62583