This page lists all described genera and species of the spider family Theraphosidae. As of August 2022, the World Spider Catalog accepted 1041 species in 156 genera:
 Acanthopelma F. O. Pickard-Cambridge, 1897
 Acanthoscurria Ausserer, 1871
 Acentropelma Pocock, 1901
 Aenigmarachne Schmidt, 2005
 Agnostopelma Pérez-Miles & Weinmann, 2010
 Aguapanela Perafán & Cifuentes, 2015
 Amazonius Cifuentes & Bertani, 2022
 Annandaliella Hirst, 1909
 Anoploscelus Pocock, 1897
 Anqasha Sherwood & Gabriel, 2022
 Antikuna Kaderka, Ferretti, West, Lüddecke & Hüsser, 2021
 Antillena Bertani, Huff & Fukushima, 2017
 Augacephalus Gallon, 2002
 Avicularia Lamarck, 1818
 Bacillochilus Gallon, 2010
 Batesiella Pocock, 1903
 Birupes Gabriel & Sherwood, 2019
 Bistriopelma Kaderka, 2015
 Bonnetina Vol, 2000
 Brachionopus Pocock, 1897
 Brachypelma Simon, 1891
 Bumba Pérez-Miles, Bonaldo & Miglio, 2014
 Cardiopelma Vol, 1999
 Caribena Fukushima & Bertani, 2017
 Catanduba Yamamoto, Lucas & Brescovit, 2012
 Catumiri Guadanucci, 2004
 Ceratogyrus Pocock, 1897
 Chaetopelma Ausserer, 1871
 Chilobrachys Karsch, 1892
 Chromatopelma Schmidt, 1995
 Citharacanthus Pocock, 1901
 Citharognathus Pocock, 1895
 Clavopelma Chamberlin, 1940
 Coremiocnemis Simon, 1892
 Cotztetlana Mendoza, 2012
 Crassicrus Reichling & West, 1996
 Cubanana Ortiz, 2008
 Cyclosternum Ausserer, 1871
 Cymbiapophysa Gabriel & Sherwood, 2020 
 Cyriocosmus Simon, 1903
 Cyriopagopus Simon, 1887
 Cyrtogrammomma Pocock, 1895
 Cyrtopholis Simon, 1892
 Davus O. Pickard-Cambridge, 1892
 Dolichothele Mello-Leitão, 1923
 Encyocratella Strand, 1907
 Encyocrates Simon, 1892
 Ephebopus Simon, 1892
 Euathlus Ausserer, 1875
 Eucratoscelus Pocock, 1898
 Eumenophorus Pocock, 1897
 Eupalaestrus Pocock, 1901
 Euphrictus Hirst, 1908
 Euthycaelus Simon, 1889
 Grammostola Simon, 1892
 Guyruita Guadanucci, Lucas, Indicatti & Yamamoto, 2007
 Hapalopus Ausserer, 1875
 Hapalotremus Simon, 1903
 Haploclastus Simon, 1892
 Haplocosmia Schmidt & von Wirth, 1996
 Harpactira Ausserer, 1871
 Harpactirella Purcell, 1902
 Hemirrhagus Simon, 1903
 Heterophrictus Pocock, 1900
 Heteroscodra Pocock, 1900
 Heterothele Karsch, 1879
 Holothele Karsch, 1879
 Homoeomma Ausserer, 1871
 Hysterocrates Simon, 1892
 Idiothele Hewitt, 1919
 Iridopelma Pocock, 1901
 Ischnocolus Ausserer, 1871
 Kankuamo Perafán, Galvis & Pérez-Miles, 2016
 Kochiana Fukushima, Nagahama & Bertani, 2008
 Lampropelma Simon, 1892
 Lasiocyano Galleti-Lima, Hamilton, Borges & Guadanucci, 2023
 Lasiodora C. L. Koch, 1850
 Lasiodorides Schmidt & Bischoff, 1997
 Longilyra Gabriel, 2014
 Loxomphalia Simon, 1889
 Loxoptygus Simon, 1903
 Lyrognathus Pocock, 1895
 Magnacarina Mendoza, Locht, Kaderka, Medina & Pérez-Miles, 2016
 Mascaraneus Gallon, 2005
 Megaphobema Pocock, 1901
 Melloina Brignoli, 1985
 Melognathus Chamberlin, 1917
 Metriopelma Becker, 1878
 Miaschistopus Pocock, 1897
 Monocentropus Pocock, 1897
 Munduruku Miglio, Bonaldo & Pérez-Miles, 2013
 Murphyarachne Sherwood & Gabriel, 2022
 Mygalarachne Ausserer, 1871
 Myostola Simon, 1903
 Neischnocolus Petrunkevitch, 1925
 Neoheterophrictus Siliwal & Raven, 2012
 Neoholothele Guadanucci & Weinmann, 2015
 Neostenotarsus Pribik & Weinmann, 2004
 Nesiergus Simon, 1903
 Nesipelma Schmidt & Kovařík, 1996
 Nhandu Lucas, 1983
 Omothymus Thorell, 1891
 Ornithoctonus Pocock, 1892
 Orphnaecus Simon, 1892
 Ozopactus Simon, 1889
 Pachistopelma Pocock, 1901
 Pamphobeteus Pocock, 1901
 Pelinobius Karsch, 1885
 Phlogiellus Pocock, 1897
 Phoneyusa Karsch, 1884
 Phormictopus Pocock, 1901
 Phormingochilus Pocock, 1895
 Phrixotrichus Simon, 1889
 Plesiopelma Pocock, 1901
 Plesiophrictus Pocock, 1899
 Poecilotheria Simon, 1885
 Proshapalopus Mello-Leitão, 1923
 Psalistops Simon, 1889
 Psalmopoeus Pocock, 1895
 Psednocnemis West, Nunn & Hogg, 2012
 Pseudhapalopus Strand, 1907
 Pseudoschizopelma Smith, 1995
 Pterinochilus Pocock, 1897
 Pterinopelma Pocock, 1901
 Reichlingia Rudloff, 2001
 Reversopelma Schmidt, 2001
 Sahydroaraneus Mirza & Sanap, 2014
 Sandinista Longhorn & Gabriel, 2019
 Schismatothele Karsch, 1879
 Schizopelma F. O. Pickard-Cambridge, 1897
 Scopelobates Simon, 1903
 Selenocosmia Ausserer, 1871
 Selenogyrus Pocock, 1897
 Selenotholus Hogg, 1902
 Selenotypus Pocock, 1895
 Sericopelma Ausserer, 1875
 Sickius Soares & Camargo, 1948
 Sphaerobothria Karsch, 1879
 Spinosatibiapalpus Gabriel & Sherwood, 2020
 Stichoplastoris Rudloff, 1997
 Stromatopelma Karsch, 1881
 Taksinus Songsangchote, Sippawat, Khaikaew & Chomphuphuang, 2022
 Tapinauchenius Ausserer, 1871
 Theraphosa Thorell, 1870
 Thrigmopoeus Pocock, 1899
 Thrixopelma Schmidt, 1994
 Tliltocatl Jorge & Oscar, 2019
 Tmesiphantes Simon, 1892
 Trichognathella Gallon, 2004
 Trichopelma Simon, 1888
 Typhochlaena C. L. Koch, 1850
 Umbyquyra Gargiulo, Brescovit & Lucas, 2018
 Vitalius Lucas, Silva & Bertani, 1993
 Xenesthis Simon, 1891
 Yanomamius Bertani & Almeida, 2021
 Ybyrapora Fukushima & Bertani, 2017