The Science, Technology and Innovation (STI) sector in Jamaica is guided by two primary institutions, the National Commission on Science and Technology (NCST) and the Scientific Research Council (SRC). Both are under the direction of the Ministry of Science, Energy, and Technology.
 Science and technology in Jamaica has a long history. In 1879, the Governor of Jamaica created the Institute of Jamaica "For the Encouragement of Literature, Science and Art in Jamaica". Jamaica was among the earliest developing countries to craft a scientific law to guide the use of science and technology for the exploitation of domestic natural resources. It was one of the first countries in the western hemisphere to gain electricity, build a railway and to use research results to boost sugar cane production. In 1960, the Scientific Research Council (SRC) was established, with a mandate to "collect, collate and review information concerning scientific research schemes or programmes relevant to the development of the resources of Jamaica (and) to establish and maintain a scientific information centre for collection and dissemination of scientific and technical information".
 Since the 1990s, the Jamaican government has set an agenda to push the development of science and technology in Jamaica. Acknowledging the pivotal role of ST&I in national development,  the Government of Jamaica formulated a national science and technology policy. The Jamaican Science and Technology Policy (1990) has two missions: 1) to improve science, technology and engineering and 2) to leverage its use to enhance societal needs. The overall goal is to make Jamaica a significant player in the arena of information technology.
 In 2009, Jamaica launched Vision 2030, a national development plan that aims to put Jamaica in a position to achieve developed country status by 2030. National Outcome 11 is a "Technology-Enabled Society", to create a more prosperous economy.
 Efforts to develop its Science and Technology educative system, through institutions such as The University of Technology, has been successful but it has been difficult to translate the results into domestic technologies, products and services because of national budgetary constraints. Expenditure on research and development (R&D) amounted to just 0.06 per cent of GDP in 2002. For comparison, the world average was 2.044 per cent. In 2018, Jamaica spent just 0.7 per cent. For comparison, the world average was over 2.2 per cent. However, recent improvements in the country's fiscal position, has enabled the government to introduce various policies to boost research expenditure and to encourage innovation. In 2019, the Jamaican government indicated that it would provide funding for research and development as of financial year 2019–20, and that effective from September 2020, it will take research and development spending into account in the calculation of the country's gross domestic product. Concerning counting R&D as a share of GDP, Finance Minister Dr Nigel Clarke said the move will stimulate greater investment in the sector, which will, in turn, drive innovation.
 According to the International Property Rights Index, Jamaica has one of the stronger intellectual property (IP) protection regimes in Latin America and the Caribbean (ranked 4th in 2020). In January 2020, the Jamaican Parliament passed the Patents and Designs Act (the "New Act"). The New Act will enable local industrial designers to secure international protection for their work in multiple jurisdictions by means of a single application, filed in one language, with one set of fees. A more efficient and streamlined patents application process will hope to foster innovation and development. The Hon. Pearnel Charles Jr, who piloted the legislation, stated "It will allow us to raise our standards and to have international compliance in several aspects and safeguard the inventors in our country. Through this Bill, [inventors] will receive much more protection, and hence there will be greater promotion of creativity and efforts to find solutions to our challenges".
 Jamaica has successfully operated a SLOWPOKE-2 nuclear reactor of 20 kW capacity since the early 1980s. It's the Caribbean's only nuclear reactor. In late 2020, Jamaica launched its Hazardous Substances Regulatory Authority (HSRA), becoming the first country in the English-speaking Caribbean to establish an independent regulatory body to ensure safety and security in the operation of facilities involving ionizing radiation and nuclear technology in the country, including the 20 kW SLOWPOKE research reactor. Minister of Industry, Investment and Commerce, Audley Shaw stated that Jamaica could now "confidently forge ahead with engaging nuclear science and technology in all aspects of national development and wealth creation strategies".
 Jamaica has a moderate ranking on the Global Innovation Index. It was ranked 78th in 2023.  In 2021, it was ranked 9th among the 18 economies in Latin America and the Caribbean and 74th out of 132 countries overall. The report highlights E-participation and Government's online service as an area of weakness to greater innovation. Broadband penetration in Jamaica stood at 77.7% in March 2021. Via the National Broadband Initiative, the Jamaican government seeks to provide Internet connection to every household by 2025.
 Caricom scientists have a modest output in terms of scientific research papers. UNESCO reports that between 2011 and 2019, output has fluctuated for most member states. Between 2017 and 2019, Caricom researchers continued to publish mostly in areas related to health sciences with Jamaica contributing over 20% of articles in this field. In terms of research density, Jamaica produced 114 publications per million inhabitants in 2019. Between 2014 and 2016, Jamaica ranked 4th in terms of average of relative citations (1.36). In terms of scientific co-authorship, between 2017 and 2019, Jamaica produced 379 publications in collaboration with the US, 118 with UK, 95 with Canada, 52 with France and 51 with Mexico.
 Notable activities that are geared towards promoting science and innovation:
 The Coding in Schools Programme: Launched in 2021, the aim is promote the teaching and learning of coding in public educational institutions across Jamaica.
 STEM Ambassador Programme: Launched in early 2021, the programme allows industry experts to encourage STEM students to achieve academic and career goals through consistent mentorship and interactive support.
 The Science Resource Centre & Innovation Laboratory: Opened in 2018, the lab is focused on the nurturing and development of revenue-generating clean technology companies within the region. It's the first facility of its kind within the Caribbean.
 The Public Wi-Fi Hotspot Programme: Jamaica has thirteen Wi-Fi-hotspots (as of September 2021), providing free public access to Internet services. Seven new locations are planned by March 2022.
 Science and Technology Fairs.
 There are several institutions involved in undertaking research:
 In 2021, two Jamaican scientists won the prestigious International Network for Government Science Advice (INGSA) 2020 awards, making Jamaica the first country to take home prizes in the organisation's two award categories in any one year.
 Jamaica has produced many internationally awarded scientists. Examples include: