D. G. Yuengling & Son, established in 1829, is the oldest operating brewing company in the United States. In 2018, by volume of sales, it was the largest craft brewery, sixth largest overall brewery and largest wholly American-owned brewery in the United States. Its headquarters are in Pottsville, Pennsylvania. In 2015, Yuengling produced about 2.9 million barrels, operating two Pennsylvania facilities and a brewery in Tampa, Florida. 
 Yuengling is an Anglicized version of Jüngling, its founder's surname and the German term for a "young person” or “youngster”. The family-owned brewery has traditionally changed ownership through the purchase of the company by the children of the previous owner. The flagship product is Yuengling Traditional Lager, an amber lager. It is popular enough in Pennsylvania and the Delaware Valley to be ordered in some bars by simply asking for a lager. From 1920 until 1985, Yuengling produced ice-cream.
 German brewer David Gottlieb Jüngling (1808–1877) immigrated to the United States in 1828 from Aldingen, near Stuttgart, in the Kingdom of Württemberg. He anglicized his surname from Jüngling to Yuengling and began the "Eagle Brewery" on Centre Street in Pottsville in 1829. His eldest son David Jr. left the Eagle Brewery to establish the James River Steam Brewery along the James River in Richmond, Virginia. The first brewery burned down in an 1831 fire and the company relocated to W. Mahantongo Street at 5th Street, its current location. The Eagle Brewery changed its name to "D. G. Yuengling and Son" in 1873 after Frederick Yuengling joined his father David in running the company. Although the company's name changed, the bald eagle remained the company's emblem. During the late 19th century, breweries were also opened in Saratoga Springs, New York City, and Trail, British Columbia. However, they were eventually merged with the Pottsville plant.
 Frank D. Yuengling began heading the company in 1899 after his father Frederick died. During the Prohibition era, Yuengling survived by producing "near beers" (beverages with a 0.5% alcohol content) called "Yuengling Special", "Yuengling Por-Tor", and "Yuengling Juvo". The company also ran a dairy which produced ice cream and opened dance halls in Philadelphia, Baltimore, and New York City.  In 1933, when Prohibition was repealed, Yuengling introduced its symbolic Winner Beer, celebrating Prohibition's repeal, and the brewery shipped a truck load of its popular brew to the White House to show their appreciation to President Roosevelt. Richard L. Yuengling Sr. and F. Dohrman Yuengling succeeded Frank Yuengling after their father's death in 1963.
 Yuengling experienced an increase in sales after a renewed interest in history due to the United States Bicentennial in 1976. Yuengling bought the rights to use the Mount Carbon (Bavarian Premium Beer) name and label when Mount Carbon Brewery went out of business in 1977. Yuengling initially brewed beer at Mount Carbon but eventually abandoned it. 
 Richard L. ("Dick") Yuengling Jr. took over as the 5th-generation company president in 1985, the same year its Pennsylvanian brewery was listed on the National Register of Historic Places as the oldest in the United States. It was also so listed in the Pennsylvania Inventory of Historic Places at some unspecified date. (The company's website mentions only a vague national and state registration in 1976). Yuengling has been a registered trademark for various merchandise, including beer, since 1995. The Pottsville brewery was featured on an episode of The History Channel's American Eats.
 In 1987, the brewery reintroduced an amber lager they had not made in decades to take advantage of a spike in popularity of heavier-style beers. Since this time, Yuengling Lager has become its flagship brand, accounting for 80% of production and much of its rapid growth. In 1990, the brewery sold 138,000 barrels.  At the time, Yuengling was the largest brewer of porter in the United States.
 In the early 1990s, demand throughout the Delaware Valley and Pennsylvania, New Jersey, and Delaware outstripped the existing brewery's abilities. In 1999, they increased their manufacturing capacity by purchasing a Stroh Brewery Company plant in Tampa, Florida, hiring the former Stroh employees, and began working with a trade union for the first time. In 2000, the company built a third brewery in Pennsylvania, in Port Carbon in Schuylkill County near Pottsville. With production at the Port Carbon, Tampa, and original Pottsville plants, the company has expanded throughout the East Coast.
 Yuengling employees filed for union decertification in 2006. As a result, Yuengling did not renew a contract with Teamsters Local 830 of Philadelphia in March 2006. In response, the trade union began boycotting Yuengling products.
 As of 2017, Yuengling is a moderately priced beer popular northward through New York, westward until Illinois and Kentucky, and southward through Georgia, where it has a large following. The Tampa brewery supplies the Florida Gulf Coast, the Florida Keys, Central Florida, North Florida, the Florida Panhandle as well as Alabama and Tennessee. The brewery uses corn from Minnesota and hops from Washington as ingredients in its products. Yuengling beer returned to Massachusetts on March 3, 2014, after having circulated among some bars and restaurants beginning in February.
 Yuengling began distribution in the state of Georgia on October 27, 2008. Yuengling also expanded distribution into West Virginia in May 2009, Ohio in October 2011, Rhode Island in June 2014, Connecticut in September 2014, Louisiana in August 2016, and Indiana in March 2017. On December 7, 2017, Yuengling announced it would expand to Arkansas in January 2018, after teasing it would expand to either that state, Kentucky, Michigan, or Texas earlier in the day on social media. Despite losing out to Arkansas, Kentucky began serving Yuengling in draft form on March 6, 2018, and began selling it for takeout use on March 19, 2018.
 Owner Dick Yuengling spoke in Harrisburg, Pennsylvania on August 26, 2013. He made his anti-union beliefs clear, calling for Pennsylvania to be a "right-to-work" state, and praising Republican governor Tom Corbett.
 A fire broke out at Yuengling's Tampa brewery on October 26, 2013. The extent of the damage was unknown.
 In February 2014, Yuengling Ice Cream returned to the market after a nearly 30-year absence. Although operated by the Yuengling family, it is operated by David Yuengling, a cousin of Dick Yuengling and a  descendant of David Gottlieb Jüngling. It is legally a separate company from the brewery, as was the case since 1935. 
 In June 2016, as part of a consent decree, Yuengling committed to paying $7 million to upgrade its water treatment facilities, as well as pay $2.8 million in fines, to settle violations of the Clean Water Act that occurred from 2008 through 2015.
 In October 2016, Dick Yuengling sparked unsuccessful calls for boycotts of Yuengling after he endorsed Donald Trump for president.
 Yuengling will transfer at least 51% control of the company in the future to either of his daughters who are currently executives, Jennifer or Wendy; he told them which one privately, but not publicly. News reports in 2019 also indicated that Yuengling's two other daughters, Debbie and Sheryl, also both work for the company, and are also "next in line to take over."
 In October 2019, Yuengling partnered with Hershey's to produce a limited release collaboration beer titled Yuengling Hershey's Chocolate Porter. This was the first collaborative beer for Yuengling in its 190-year history. The drink tastes like traditional Yuengling but has an aftertaste of Hershey's Special Dark.
 In 2021, Yuengling announced its expansion into Texas through a partnership that have its beer brewed at a Molson Coors' facility in Fort Worth.