This Week in Synthetic Biology #3
By: Niko Mccarty
Tags: News, Biotechnology, Biology, Newsletter, Genetic Engineering

More research…

A three-way combinatorial CRISPR screen for analyzing interactions among druggable targets by Zhou, P. et al. in Cell Reports. (Open Access)

Application of CRISPR-Cas12a enhanced fluorescence assay coupled with nucleic acid amplification for the sensitive detection of African swine fever virus by Tao, G. et al. in ACS Synthetic Biology.

A versatile genetic control system in mammalian cells and mice responsive to clinically licensed sodium ferulate by Wang, Y. et al. in Science Advances. (Open Access)

Bacterial mock communities as standards for reproducible cytometric microbiome analysis by Cichocki, N. et al. in Nature Protocols.

Bacterial synthesis of C3-C5 diols via extending amino acid catabolism by Wang, J., et al. in PNAS.

Comprehensive study on Escherichia coli genomic expression: Does position really matter? by Goormans, A.R. et al. in Metabolic Engineering.

CRISPR-Cas13d Induces Efficient mRNA Knockdown in Animal Embryos by Kushawah, G. et al. in Developmental Cell. Read the press release.

De novo rational design of a freestanding, supercharged polypeptide, proton-conducting membrane by Ma, C. et al. in Science Advances. (Open Access)

Developing methods to circumvent the conundrum of chromosomal rearrangements occurring in multiplex gene edition [sic] by Borsenberger, V. et al. in ACS Synthetic Biology.

Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold by Carrasco-López, C. et al. in Nature Communications. (Open Access)

Directed evolution of Pseudomonas fluorescens lipase variants with improved thermostability using error-prone PCR by Guan, L. et al. in Frontiers in Bioengineering and Biotechnology.

DNA Scanner: a web application for comparing DNA synthesis feasibility, price, and turnaround time across vendors by Doçi, G. et al. in Synthetic Biology. (Open Access)

Engineering combinatorial and dynamic decoders using synthetic immediate-early genes by Ravindran, P.T. et al. in Communications Biology. (Open Access)

Engineering designer beta cells with a CRISPR-Cas9 conjugation platform by Lim, D. et al. in Nature Communications. (Open Access)

Engineering isoprenoid quinone production in yeast by Kaur, D. et al. in ACS Synthetic Biology.

Engineering of the 2,3-butanediol pathway of Paenibacillus polymyxa DSM 365 by Schilling, C. et al. in Metabolic Engineering. (Open Access)

Engineering regulatory networks for complex phenotypes in E. coli by Liu, R. et al. in Nature Communications. (Open Access)

Evaluating and engineering Saccharomyces cerevisiae promoters for increased amylase expression and bioethanol production from raw starch by Myburgh, M.W., Rose, S.H. and Viljoen-Bloom, M. in FEMS Yeast Research.

Fully biological production of adipic acid analogs from branched catechols by Kruyer, N.S. et al. in Scientific Reports. (Open Access)

Genetically encoded tags for direct synthesis of EM-visible gold nanoparticles in cells by Jiang, Z. et al. in Nature Methods.

Independent component analysis of E. coli’s transcriptome reveals the cellular processes that respond to heterologous gene expression by Tan, J. et al. in Metabolic Engineering. (Open Access)

In silico co-factor balance estimation using constraint-based modelling informs metabolic engineering in Escherichia coli by de Arroyo Garcia, L. and Jones, P.R. in PLoS Computational Biology. (Open Access)

Metabolically engineered Caldicellulosiruptor bescii as a platform for producing acetone and hydrogen from lignocellulose by Straub, C.T. et al. in Biotechnology and Bioengineering.

One-pot synthesis of adipic acid from guaiacol in Escherichia coli by Suitor, J.T., Varzandeh, S. and Wallace, S. in ACS Synthetic Biology.

Optogenetic control of protein binding using light-switchable nanobodies by Gil, A.A. et al. in Nature Communications. (Open Access)

Preliminary engineering for in situ in vivo bioprinting: a novel micro bioprinting platform for in situ in vivo bioprinting at a gastric wound site by Zhao, W. and Xu, T. in Biofabrication (Open Access)

Read the press release.

Regulatory control circuits for stabilizing long-term anabolic product formation in yeast by D’Ambrosio, V. et al. in Metabolic Engineering. (Open Access)

Synthetic cross-phyla gene replacement and evolutionary assimilation of major enzymes by Sandberg, T.E. et al. in Nature Ecology & Evolution.

Synthetic protease-activated class B GPCRs by Willard, F.S. et al. in Biochemical and Biophysical Research Communications.

Unveiling of swainsonine biosynthesis via a multi-branched pathway in fungi by Luo, F. et al. in ACS Chemical Biology.