allergies are being warned against the Pfizer vaccine
Tags: Freelance

Severe allergic reactions to vaccines are extremely rare, with anaphylaxis occurring after approximately one per million vaccine doses. Most reactions reported as possible allergic reactions to vaccines are most likely not true allergies.

Regardless, every person is normally asked about their medical history by their immunization provider, including whether they have any known allergies, especially to a vaccine or its ingredients, before being vaccinated.

As almost all severe allergic reactions occur within 15 minutes of exposure to the trigger, it is common around the world to monitor patients for at least

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Hourse • Sun, 11:34 AM

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Aren’t clinical trials supposed to pick up issues like this?

People with a history of severe allergic reaction to a vaccine or to any ingredient of the Pfizer/BioNTech vaccine were not included in the late phase clinical trial for this vaccine.

This is a precaution designed to protect the safety of the trial participants. Clinical trials usually focus on healthy people without underlying medical conditions, although the Pfizer phase 2/3 trial allowed enrolment of people with stable pre-existing chronic conditions.

Once the safety and effectiveness of a vaccine is well-established in healthy people, it can then be offered to other populations, such as people with severe underlying medical conditions.

This trial includes more than 40,000 participants and has shown the vaccine to be safe and well tolerated, with no serious safety concerns. The incidence of allergic-type symptoms after vaccination was slightly higher in the vaccinated group at 0.63% compared with the placebo group at 0.51%, however it is not clear whether this slight difference is due to chance.

What are the implications for people with significant allergies?

As to the implications of this latest news for people with significant allergies, it’s too early to tell. We still don’t know if these reports were true allergic reactions.

There is also no theoretical reason to suspect allergic reactions would be more common with Covid-19 vaccines than with other vaccines, even those using newer technologies.

As always, people should discuss their medical history with their vaccine provider, including any history of allergy.

We still need ongoing monitoring

Given Covid-19 vaccines will be delivered to millions of people around the world, it’s inevitable some adverse events will be reported. There is potential for an adverse reaction with any medication or vaccine, and that’s why people are monitored after being given a vaccine. A consideration of the risks and benefits is always important when considering whether to have a vaccine.