Date: 202012
Local time of day: 0001-0600
Location: ZZZ.Airport, US
Flight conditions: Mixed
Aircraft: Commercial Fixed Wing
Operator: Air Carrier
Operating under: Part 121
Flight plan: IFR
Mission: Passenger
Flight phase: Taxi
Reporter organization: Air Carrier
Reporter function: Pilot Flying; Captain
Reporter qualification: Flight Crew Instrument; Flight Crew Multiengine; Flight Crew Air Transport Pilot (ATP)
Human factors: Situational Awareness; Time Pressure; Communication Breakdown; Confusion; Distraction; Human-Machine Interface
Anomaly: Deviation / Discrepancy - Procedural Clearance; Deviation / Discrepancy - Procedural Published Material / Policy; Ground Incursion Taxiway
Detector: Person Flight Crew
When detected: Taxi
Result: Flight Crew Became Reoriented
Contributing factors: Airport; Weather
Primary problem: Airport

Narrative: Well; fatigue did play a role.  It slowed us down.  Earlier the hotel we were at started with construction outside at XA:00 am.  This flight was already an hour late; and it was XO:30 pm at night before we could even taxi.  I might also need to use the tools the Ipad has to draw a taxi route when I am not super familiar with the airport.  Yes this is a hub for us; but the deice pad was in a place I [had] never been to.The First Officer was also overly concerned about cleaning the aircraft flight deck due to the COVID virus; as we changed planes from an earlier flight.  I was having a slight reaction to the spray as I breathe it in; which gave me a allergy response.  I had to step out of the flight deck for a few minutes. So my pre-flight taxi brief was lacking and I should of and will going forward instruct my future First Officer's that I need the extra set of eyes outside.On top of that; I will send an email of my concern for the proper use of this spray.  We don't have much guidance on it.After being de-iced on the X taxi pad area; we were given taxi instructions to cross Runway XXR-XXL at Taxiway F; but the instruction to get there was a little vague because we started on Taxiway H. Because the ground being covered by snow; the taxi signs became the primary way to identify the taxiways; the painted tarmac signs were covered by snow. I believed I passed Taxiway F because the sign was further away and I was distracted because the First Officer was having difficulty with the de-ice checklist and holdover times.  I then (most likely) made a left turn on Taxiway Bravo and right turn down Taxiway V.  While on Taxiway V and approaching the intersection of Taxiway Y & V; I made an all stop as I was confused and approaching two runway intersections.I saw I went past Taxiway F and then had to get my bearings where I was.  I declared to the First officer that I was lost and needed help.  Once I figured out where I was; ground control gave me a new set of taxi instructions.  The ground controller did not seem to be too concerned about the taxi deviation. However; at the time the confusion was real and I did not want to cross a runway without figuring out where I exactly was.After this I brought CRM back into the game and had a frank discussion with the First Officer.  I told her that I can't taxi the plane and look up deice holdover data at the same time; and that the current issue is that we don't have much time to mess around with since we only used type 1 fluid (15 min).  I then asked her that it looked like it stopped snowing anyways; so would she agree or disagree to that assessment?  She did so we proceeded to taxi to takeoff.




Synopsis: Air carrier Captain reported a taxiway incursion and cited fatigue; weather and signage issues as contributing factors.