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brands.csv CHANGED
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+ Abrilada,Actemra,Actemra ACTPen,Actemra Subcutaneous Injection,Adalicip,Amgevita,Brenzys,Cimzia,Cosentyx,Enbrel,Hadlima,Humira,Hyrimoz,Idacio,Inflectra,Olumiant,Orencia,Orencia ClickJect,Remicade,Remsima SC,Renflexis,Rinvoq,Saphnelo,Simponi,Stelara,Taltz,Tremfya,Xeljanz,Yuflyma
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+ A,d,a,l,i,c,i,p
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combinations.csv CHANGED
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drugs.csv CHANGED
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+ abatacept,adalimumab,anifrolumab,baricitinib,certolizumab pegol,etanercept,golimumab,guselkumab,infliximab,ixekizumab,secukinumab,tocilizumab,tofacitinib,upadacitinib,ustekinumab
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formulations.csv CHANGED
@@ -1 +1,36 @@
1
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+ Concentrate for injection 200 mg in 10 mL,Concentrate for injection 400 mg in 20 mL,Concentrate for injection 80 mg in 4 mL,Injection 100 mg in 1 mL single use pre-filled pen,Injection 100 mg in 1 mL single use pre-filled syringe,Injection 125 mg in 1 mL single dose autoinjector,Injection 125 mg in 1 mL single dose pre-filled syringe,Injection 150 mg in 1 mL pre-filled pen,Injection 162 mg in 0.9 mL single use pre-filled pen,Injection 162 mg in 0.9 mL single use pre-filled syringe,Injection 20 mg in 0.2 mL pre-filled syringe,Injection 20 mg in 0.4 mL pre-filled syringe,Injection 200 mg in 1 mL single use pre-filled syringe,Injection 40 mg in 0.4 mL pre-filled pen,Injection 40 mg in 0.4 mL pre-filled syringe,Injection 40 mg in 0.8 mL pre-filled pen,Injection 40 mg in 0.8 mL pre-filled syringe,Injection 45 mg in 0.5 mL,Injection 50 mg in 0.5 mL single use pre-filled pen,Injection 50 mg in 0.5 mL single use pre-filled syringe,"Injection 50 mg in 1 mL single use auto-injector, 4",Injection 80 mg in 1 mL single dose pre-filled pen,Injection set containing 4 vials powder for injection 25 mg and 4 pre-filled syringes solvent 1 mL,"Injections 50 mg in 1 mL single use pre-filled syringes, 4","Oral solution 1 mg per mL, 240 mL",Powder for I.V. infusion 100 mg,Powder for I.V. infusion 250 mg,Solution concentrate for I.V. infusion 300 mg in 2 mL,Solution for injection 120 mg in 1 mL pre-filled pen,Solution for injection 120 mg in 1 mL pre-filled syringe,Solution for injection 200 mg in 1 mL pre-filled pen,Tablet 15 mg,Tablet 2 mg,Tablet 4 mg,Tablet 5 mg
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+ I,n,j,e,c,t,i,o,n, ,1,5,0, ,m,g, ,i,n, ,1, ,m,L, ,p,r,e,-,f,i,l,l,e,d, ,p,e,n
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hospital_types.csv CHANGED
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+ Any,Private,Public
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+ P,u,b,l,i,c
indications.csv CHANGED
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+ ankylosing spondylitis,giant cell arteritis,juvenile idiopathic arthritis,non-radiographic axial spondyloarthritis,psoriatic arthritis,rheumatoid arthritis,systemic lupus erythematosus
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+ a,n,k,y,l,o,s,i,n,g, ,s,p,o,n,d,y,l,i,t,i,s
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treatment_phases.csv CHANGED
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+ Balance of supply (including switching formulation) where the full duration of treatment available under a particular treatment phase was not requested in the preceding prescription,Balance of supply for Initial treatment - Initial 1 (new patient) or Initial 2 (retrial or recommencement of treatment after a break of less than 12 months) or Initial 3 (recommencement of treatment after a break of more than 12 months),Balance of supply for Initial treatment - Initial 1 (new patient) or Initial 2 (retrial or recommencement of treatment after a break of less than 12 months) or Initial 3 (recommencement of treatment after a break of more than 12 months) - in a patient of any weight being administered a subcutaneous form of this biological medicine,"Balance of supply for Initial treatment, Continuing treatment - subcutaneous form",Continuing Treatment - balance of supply,Continuing or recommencement of treatment (within 12 months of a treatment break),Continuing treatment,Continuing treatment - balance of supply,Continuing treatment in a patient weighing at least 30 kg,Continuing treatment in a patient weighing less than 30 kg,Continuing treatment with subcutaneous form or switching from intravenous form to subcutaneous form,First Continuing treatment,First Continuing treatment - balance of supply,First continuing treatment,First continuing treatment - balance of supply,"Initial 1 (New patient), Initial 2 (Change or re-commencement of treatment after a break in biological medicine of less than 5 years) or Initial 3 (Recommencement of treatment after a break in biological medicine of more than 5 years) - balance of supply","Initial 1 (New patient), Initial 2 (Change or re-commencement of treatment after a break in biological medicine of less than 5 years) or Initial 3 (recommencement of treatment after a break in biological medicine of more than 5 years) - balance of supply","Initial 1 (New patient), Initial 2 (Change or recommencement of treatment after a break in biological medicine of less than 5 years) or Initial 3 (Recommencement of treatment after a break in biological medicine of more than 5 years) - balance of supply",Initial 1 (new patient) or Initial 2 (change or recommencement of treatment after a break in biological medicine of less than 12 months) or Initial 3 (recommencement of treatment after a break in biological medicine of more than 12 months) - balance of supply,Initial 1 (new patient) or Initial 2 (change or recommencement of treatment after a break in biological medicine of less than 24 months) or Initial 3 (recommencement of treatment after a break in biological medicine of more than 24 months) - balance of supply,Initial 1 (new patient) or Initial 2 (change or recommencement of treatment after a break in biological medicine of less than 5 years) or Initial 3 (recommencement of treatment after a break in biological medicine of more than 5 years) - balance of supply,Initial treatment,Initial treatment - Initial 1 (New patient),Initial treatment - Initial 1 (new patient weighing at least 30 kg),Initial treatment - Initial 1 (new patient weighing less than 30 kg),Initial treatment - Initial 1 (new patient),Initial treatment - Initial 1 (new patient) or Initial 2 (change or recommencement of treatment after a break in biological medicine of less than 12 months) or Initial 3 (recommencement of treatment after a break in biological medicine of more than 12 months) - balance of supply,Initial treatment - Initial 1 (new patient) or Initial 2 (change or recommencement of treatment after break of less than 24 months) or Initial 3 (recommencement of treatment after a break in biological medicine of more than 24 months) - balance of supply,"Initial treatment - Initial 1 (new patient), Initial 2 (change or recommencement of treatment after a break in biological medicine of less than 5 years) or Initial 3 (recommencement of treatment after a break in biological medicine of more than 5 years) - balance of supply","Initial treatment - Initial 1 (new patient), Initial 2 (change or recommencement of treatment after a break in medicine of less than 5 years) or Initial 3 (recommencement of treatment after a break in biological medicine of more than 5 years) - balance of supply",Initial treatment - Initial 2 (Change or re-commencement of treatment after a break in biological medicine of less than 5 years),Initial treatment - Initial 2 (Change or re-commencement of treatment after a break of less than 5 years),Initial treatment - Initial 2 (Change or recommencement of treatment after a break in biological medicine of less than 5 years),Initial treatment - Initial 2 (change or recommencement of treatment after a break in biological medicine of less than 12 months),Initial treatment - Initial 2 (change or recommencement of treatment after a break in biological medicine of less than 24 months),Initial treatment - Initial 2 (change or recommencement of treatment after a break in biological medicine of less than 5 years),Initial treatment - Initial 2 (change or recommencement of treatment after a break in in biological medicine of less than 5 years),Initial treatment - Initial 2 (change or recommencement of treatment after break in biological medicine of less than 24 months),Initial treatment - Initial 2 (retrial or recommencement of treatment after a break of less than 12 months in a patient weighing at least 30 kg),Initial treatment - Initial 2 (retrial or recommencement of treatment after a break of less than 12 months in a patient weighing less than 30 kg),Initial treatment - Initial 2 (retrial or recommencement of treatment after a break of less than 12 months),Initial treatment - Initial 3 (Recommencement of treatment after a break in biological medicine of more than 5 years),Initial treatment - Initial 3 (recommencement of a new treatment cycle after a break of more than 12 months in a patient weighing less than 30 kg),Initial treatment - Initial 3 (recommencement of treatment after a break in biological medicine of more than 12 months),Initial treatment - Initial 3 (recommencement of treatment after a break in biological medicine of more than 24 months),Initial treatment - Initial 3 (recommencement of treatment after a break in biological medicine of more than 5 years),Initial treatment - Initial 3 (recommencement of treatment after a break of more than 12 months in a patient weighing at least 30 kg),Initial treatment - Initial 3 (recommencement of treatment after a break of more than 12 months),Initial treatment - Initial 4 (Temporary listing - change of treatment from another biological medicine to tocilizumab after resolution of the critical shortage of tocilizumab),Initial treatment - Initial 4 (Temporary listing - change of treatment from another biological medicine to tocilzumab after resolution of the critical shortage of tocilizumab),Initial treatment with the subcutaneous form where a concurrent PBS authority application for the intravenously (IV) administered formulation is being made,Subsequent continuing treatment,Transitioning from non-PBS to PBS-subsidised supply - Grandfather arrangements
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+ B,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y, ,f,o,r, ,I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t,), ,o,r, ,I,n,i,t,i,a,l, ,2, ,(,r,e,t,r,i,a,l, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,l,e,s,s, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,m,o,r,e, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,)
4
+ B,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y, ,f,o,r, ,I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t,), ,o,r, ,I,n,i,t,i,a,l, ,2, ,(,r,e,t,r,i,a,l, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,l,e,s,s, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,m,o,r,e, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,), ,-, ,i,n, ,a, ,p,a,t,i,e,n,t, ,o,f, ,a,n,y, ,w,e,i,g,h,t, ,b,e,i,n,g, ,a,d,m,i,n,i,s,t,e,r,e,d, ,a, ,s,u,b,c,u,t,a,n,e,o,u,s, ,f,o,r,m, ,o,f, ,t,h,i,s, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e
5
+ B,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y, ,f,o,r, ,I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t,",", ,C,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t, ,-, ,s,u,b,c,u,t,a,n,e,o,u,s, ,f,o,r,m
6
+ C,o,n,t,i,n,u,i,n,g, ,T,r,e,a,t,m,e,n,t, ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
7
+ C,o,n,t,i,n,u,i,n,g, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,(,w,i,t,h,i,n, ,1,2, ,m,o,n,t,h,s, ,o,f, ,a, ,t,r,e,a,t,m,e,n,t, ,b,r,e,a,k,)
8
+ C,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t
9
+ C,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t, ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
10
+ C,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t, ,i,n, ,a, ,p,a,t,i,e,n,t, ,w,e,i,g,h,i,n,g, ,a,t, ,l,e,a,s,t, ,3,0, ,k,g
11
+ C,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t, ,i,n, ,a, ,p,a,t,i,e,n,t, ,w,e,i,g,h,i,n,g, ,l,e,s,s, ,t,h,a,n, ,3,0, ,k,g
12
+ C,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t, ,w,i,t,h, ,s,u,b,c,u,t,a,n,e,o,u,s, ,f,o,r,m, ,o,r, ,s,w,i,t,c,h,i,n,g, ,f,r,o,m, ,i,n,t,r,a,v,e,n,o,u,s, ,f,o,r,m, ,t,o, ,s,u,b,c,u,t,a,n,e,o,u,s, ,f,o,r,m
13
+ F,i,r,s,t, ,C,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t
14
+ F,i,r,s,t, ,C,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t, ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
15
+ F,i,r,s,t, ,c,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t
16
+ F,i,r,s,t, ,c,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t, ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
17
+ I,n,i,t,i,a,l, ,1, ,(,N,e,w, ,p,a,t,i,e,n,t,),",", ,I,n,i,t,i,a,l, ,2, ,(,C,h,a,n,g,e, ,o,r, ,r,e,-,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,R,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
18
+ I,n,i,t,i,a,l, ,1, ,(,N,e,w, ,p,a,t,i,e,n,t,),",", ,I,n,i,t,i,a,l, ,2, ,(,C,h,a,n,g,e, ,o,r, ,r,e,-,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
19
+ I,n,i,t,i,a,l, ,1, ,(,N,e,w, ,p,a,t,i,e,n,t,),",", ,I,n,i,t,i,a,l, ,2, ,(,C,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,R,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
20
+ I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t,), ,o,r, ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,), ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
21
+ I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t,), ,o,r, ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,2,4, ,m,o,n,t,h,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,2,4, ,m,o,n,t,h,s,), ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
22
+ I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t,), ,o,r, ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
23
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t
24
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,1, ,(,N,e,w, ,p,a,t,i,e,n,t,)
25
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t, ,w,e,i,g,h,i,n,g, ,a,t, ,l,e,a,s,t, ,3,0, ,k,g,)
26
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t, ,w,e,i,g,h,i,n,g, ,l,e,s,s, ,t,h,a,n, ,3,0, ,k,g,)
27
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t,)
28
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t,), ,o,r, ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,), ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
29
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t,), ,o,r, ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,b,r,e,a,k, ,o,f, ,l,e,s,s, ,t,h,a,n, ,2,4, ,m,o,n,t,h,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,2,4, ,m,o,n,t,h,s,), ,-, , ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
30
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t,),",", ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
31
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,1, ,(,n,e,w, ,p,a,t,i,e,n,t,),",", ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,o,r, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,5, ,y,e,a,r,s,), ,-, ,b,a,l,a,n,c,e, ,o,f, ,s,u,p,p,l,y
32
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,C,h,a,n,g,e, ,o,r, ,r,e,-,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,)
33
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,C,h,a,n,g,e, ,o,r, ,r,e,-,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,)
34
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,C,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,)
35
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,)
36
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,2,4, ,m,o,n,t,h,s,)
37
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,)
38
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,5, ,y,e,a,r,s,)
39
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,c,h,a,n,g,e, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,l,e,s,s, ,t,h,a,n, ,2,4, ,m,o,n,t,h,s,)
40
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,r,e,t,r,i,a,l, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,l,e,s,s, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s, ,i,n, ,a, ,p,a,t,i,e,n,t, ,w,e,i,g,h,i,n,g, ,a,t, ,l,e,a,s,t, ,3,0, ,k,g,)
41
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,r,e,t,r,i,a,l, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,l,e,s,s, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s, ,i,n, ,a, ,p,a,t,i,e,n,t, ,w,e,i,g,h,i,n,g, ,l,e,s,s, ,t,h,a,n, ,3,0, ,k,g,)
42
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,2, ,(,r,e,t,r,i,a,l, ,o,r, ,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,l,e,s,s, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,)
43
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,3, ,(,R,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,5, ,y,e,a,r,s,)
44
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,a, ,n,e,w, ,t,r,e,a,t,m,e,n,t, ,c,y,c,l,e, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,m,o,r,e, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s, ,i,n, ,a, ,p,a,t,i,e,n,t, ,w,e,i,g,h,i,n,g, ,l,e,s,s, ,t,h,a,n, ,3,0, ,k,g,)
45
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,)
46
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,2,4, ,m,o,n,t,h,s,)
47
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,i,n, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,o,f, ,m,o,r,e, ,t,h,a,n, ,5, ,y,e,a,r,s,)
48
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,m,o,r,e, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s, ,i,n, ,a, ,p,a,t,i,e,n,t, ,w,e,i,g,h,i,n,g, ,a,t, ,l,e,a,s,t, ,3,0, ,k,g,)
49
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,3, ,(,r,e,c,o,m,m,e,n,c,e,m,e,n,t, ,o,f, ,t,r,e,a,t,m,e,n,t, ,a,f,t,e,r, ,a, ,b,r,e,a,k, ,o,f, ,m,o,r,e, ,t,h,a,n, ,1,2, ,m,o,n,t,h,s,)
50
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,4, ,(,T,e,m,p,o,r,a,r,y, ,l,i,s,t,i,n,g, ,-, ,c,h,a,n,g,e, ,o,f, ,t,r,e,a,t,m,e,n,t, ,f,r,o,m, ,a,n,o,t,h,e,r, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,t,o, ,t,o,c,i,l,i,z,u,m,a,b, ,a,f,t,e,r, ,r,e,s,o,l,u,t,i,o,n, ,o,f, ,t,h,e, ,c,r,i,t,i,c,a,l, ,s,h,o,r,t,a,g,e, ,o,f, ,t,o,c,i,l,i,z,u,m,a,b,)
51
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,-, ,I,n,i,t,i,a,l, ,4, ,(,T,e,m,p,o,r,a,r,y, ,l,i,s,t,i,n,g, ,-, ,c,h,a,n,g,e, ,o,f, ,t,r,e,a,t,m,e,n,t, ,f,r,o,m, ,a,n,o,t,h,e,r, ,b,i,o,l,o,g,i,c,a,l, ,m,e,d,i,c,i,n,e, ,t,o, ,t,o,c,i,l,z,u,m,a,b, ,a,f,t,e,r, ,r,e,s,o,l,u,t,i,o,n, ,o,f, ,t,h,e, ,c,r,i,t,i,c,a,l, ,s,h,o,r,t,a,g,e, ,o,f, ,t,o,c,i,l,i,z,u,m,a,b,)
52
+ I,n,i,t,i,a,l, ,t,r,e,a,t,m,e,n,t, ,w,i,t,h, ,t,h,e, ,s,u,b,c,u,t,a,n,e,o,u,s, ,f,o,r,m, ,w,h,e,r,e, ,a, ,c,o,n,c,u,r,r,e,n,t, ,P,B,S, ,a,u,t,h,o,r,i,t,y, ,a,p,p,l,i,c,a,t,i,o,n, ,f,o,r, ,t,h,e, ,i,n,t,r,a,v,e,n,o,u,s,l,y, ,(,I,V,), ,a,d,m,i,n,i,s,t,e,r,e,d, ,f,o,r,m,u,l,a,t,i,o,n, ,i,s, ,b,e,i,n,g, ,m,a,d,e
53
+ S,u,b,s,e,q,u,e,n,t, ,c,o,n,t,i,n,u,i,n,g, ,t,r,e,a,t,m,e,n,t
54
+ T,r,a,n,s,i,t,i,o,n,i,n,g, ,f,r,o,m, ,n,o,n,-,P,B,S, ,t,o, ,P,B,S,-,s,u,b,s,i,d,i,s,e,d, ,s,u,p,p,l,y, ,-, ,G,r,a,n,d,f,a,t,h,e,r, ,a,r,r,a,n,g,e,m,e,n,t,s