Complex sentence: The cities of Santa Cruz and San Cristobal de La Laguna and urban are physically linked, so that together have a population of over 382,331 inhabitants, making them the largest urban area in the Canaries (independent of municipal lines).
Split into simpler sentences: The cities of Santa Cruz and San Cristobal de La Laguna and urban are physically linked, so that together have a population of over 382,331 inhabitants. What makes them the largest urban area in the Canaries (independent of municipal lines).