Complex sentence: During bladder filling, neurons within the PMC are turned off, but at a critical level of bladder distention, the afferent activity arising from mechanoreceptors in the bladder wall switches the PMC on and enhances its activity.
Split into simpler sentences: During bladder filling, neurons within the PMC are turned off. However, at a critical level of bladder distention, the afferent activity arising from mechanoreceptors in the bladder wall switches the PMC on and enhances its activity.