Complex sentence: Springfield's nickname is the Queen City of the Ozarks and is known as the Birthplace of Route 66 as well as the home of several universities including Missouri State University, Drury University, and Evangel University.
Split into simpler sentences: Springfield's nickname is the "Queen City of the Ozarks" and is known as the "Birthplace of Route 66". It is also home of several universities including Missouri State University, Drury University, and Evangel University.