Complex sentence: For example, an English speaker unfamiliar with Japanese would probably be understood if he attempted to pronounce "Shinjuku" (in Hepburn), whereas an attempt to read the Kunrei-shiki spelling "Sinzyuku" would likely not be comprehensible.
Split into simpler sentences: For example, an English speaker unfamiliar with Japanese language would probably be misunderstood if he read the Kunrei-shiki spelling "Sinzyuku" with an attempt to express "Shinjuku" in Hepburn Romanization. Thus, an attempt to read the Kunrei-shiki spelling sometimes would fail to be comprehensible.