Complex sentence: Families can often play a crucial role in the care of those who would typically be placed in long-term treatment centers; however, many mentally ill people are resistant to such help, due to the nature of their conditions.
Split into simpler sentences: Families can often play a crucial role in the care of those who would typically be placed in long-term treatment centers. However, many mentally ill people are resistant to such help due to the nature of their conditions.