Complex sentence: From early on in the story, the crew is accompanied by, a female pirate out to make Luffy "her man", and following Buggy's escape from Impel Down a group of other escapees join the crew.
Split into simpler sentences: From early on in the story, the crew is accompanied by, a female pirate out to make Luffy "her man". Upon Buggy's escape from Impel Down, later in the series, a group of other escapees join the crew.