Complex sentence: Vinca alkaloids and Taxanes are the two main groups of anti-microtubule agents, and although both of these groups of drugs cause microtubule disfunction, their mechanisms of action are completely opposite.
Split into simpler sentences: Vinca alkaloids and Taxanes are the two main groups of anti-microtubule agents. Although both of these groups of drugs cause microtubule disfunction, their mechanisms of action are completely opposite.