Complex sentence: GPR65 (TDAG8) is primarily expressed in lymphoid tissues (spleen, lymph nodes, thymus, and leukocytes), and as a GPCR, it is localized to the plasma membrane.
Split into simpler sentences: GPR65 (TDAG8) is primarily expressed in lymphoid tissues (spleen, lymph nodes, thymus, and leukocytes). As a GPCR, GPR65 is localized to the plasma membrane.