Complex sentence: In case of neurons it is known to be expressed strongly in the mature axon, and axon hillock (neuronal equivalent of tight junction) can act as a barrier for its lateral spread even though it has no transmembrane segment.
Split into simpler sentences: In case of neurons it is known to be expressed strongly in the mature axon. Axon hillock (neuronal equivalent of tight junction) can act as a barrier for its lateral spread even though it has no transmembrane segment.