Complex sentence: In two Phase 1 trials that included 81 oncology patients, bardoxolone methyl reduced serum creatinine levels, with a corresponding improvement in estimated glomerular filtration rate (eGFR).
Split into simpler sentences: In two Phase 1 trials that included 81 oncology patients, the following were demonstrated. Also, in these Phase 1 trials, bardoxolone methyl reduced serum creatinine levels, with a corresponding improvement in estimated glomerular filtration rate (eGFR).