Complex sentence: Studies on mtDNA and microsatellite loci indicate that wolves have hybridized extensively with coyotes in the northeastern USA and southeastern Canada, with the frequency of coyote haplotypes in wolves tending to increase to the east, from 50% in Minnesota, to 100% in southern Quebec.
Split into simpler sentences: Studies on mtDNA and microsatellite loci indicate that wolves have hybridized extensively with coyotes in Minnesota and eastern Canada. The frequency of coyote haplotypes in wolves tends to increase to the east, from 50% in Minnesota, to 100% in southern Quebec.