Complex sentence: A main side effect associated with all mitotic inhibitors is peripheral neuropathy, which is a numbness or tingling in the hands and feet due to peripheral nerve damage that can become so severe, reduction in dosage or complete cessation of the drug may be required.
Split into simpler sentences: A main side effect associated with all mitotic inhibitors is peripheral neuropathy, which is a numbness or tingling in the hands and feet due to peripheral nerve damage. It can become so severe that reduction in dosage or complete cessation of the drug may be required.