Complex sentence: The use of LPD-824 has had a minor spike between 2006 and 2007 but after this time frame, virtually no reports of LPD-824 use have been documented.
Split into simpler sentences: The use of LPD-824 has had a minor spike between 2006 and 2007. After this time frame, virtually no reports of LPD-824 use have been documented.