Complex sentence: Allostatic load specifically refers to a composite index of indicators of cumulative strain on multiple organs and tissues which accumulates via the wear and tear associated with acute shifts in physiologic activity in response to negative stimuli.
Split into simpler sentences: Allostatic load specifically refers to a composite index of indicators of cumulative strain on multiple organs and tissues. Accumulates via the wear and tear associated with acute shifts in physiologic activity in response to negative stimuli.