Complex sentence: The award-winning Great Lakes Brewing Company, is located on W.28th Street in Ohio City, with its brewpub on Market Avenue (adjacent to the West Side Market) occupying a building that formerly housed the Market Tavern, a pub frequented by Elliot Ness.
Split into simpler sentences: The award-winning Great Lakes Brewing Company is located on W.28th Street in Ohio City. Its brewpub on Market Avenue (adjacent to the West Side Market) occupies a building that formerly housed the Market Tavern, a pub frequented by Elliot Ness.