Complex sentence: In a general sense, biospheres are any closed, self-regulating systems containing ecosystems; including artificial ones such as Biosphere 2 and BIOS-3; and, potentially, ones on other planets or moons.
Split into simpler sentences: In a general sense, biospheres are any closed, self-regulating systems containing ecosystems. This includes artificial biospheres such as Biosphere 2 and BIOS-3, and potentially ones on other planets or moons.