Complex sentence: Therapy with ascorbic acid and methylene blue may be effective, however, since methylene blue requires the presence of NADPH that requires normal functioning of G6PD system, it is less effective than in other conditions characterized by hemoglobin oxidation.
Split into simpler sentences: Therapy with ascorbic acid and methylene blue may be effective. However, since methylene blue requires the presence of NADPH that requires normal functioning of G6PD system, it is less effective than in other conditions characterized by hemoglobin oxidation.