Complex sentence: The Convent of the Visitation was founded in 1643 during a period of heavy famine, with the town again undergoing a series of poor harvests combined with an attack of the plague between the years 1648-1653.
Split into simpler sentences: The Convent of the Visitation was founded in 1643 during a period of severe famine. The town suffered a series of poor harvests as well as an outbreak of the plague between the years 1648-1653.