Complex sentence: In reactions, the exact structure of lithium enolates are often difficult to determine, as it is common for organolithium reagents to form complex mixed-aggregates with solvent as well as substrate molecules in reaction.
Split into simpler sentences: In reactions, the exact structure of lithium enolates are often difficult to determine, as mixed aggregates are formed with organolithium reagents and solvents. It is common for organolithium reagents to form complex mixed-aggregates with solvent as well as substrate molecules in reaction.