Complex sentence: The majority of cases are systemic in nature, often causing fungemia in patients with underlying disease or immunosuppression, such as cancer, leukemia, and transplant and AIDS patients most likely to develop systemic infection.
Split into simpler sentences: The majority of cases are systemic in nature, often causing fungemia in patients with underlying disease or immunosuppression. Cases have been reported in cancer, leukemia, and transplant patients, with AIDS patients most likely to develop systemic infection.