Complex sentence: One of the early settlers in town was Dr. Samuel Green, who lived in a house at 2 Charlton St. in Greenville (which is now part of Rochdale, a village in Leicester).
Split into simpler sentences: One of the early settlers in town was a Dr. Samuel Green. He lived at 2 Charlton St., in Greenville (which is now part of Rochdale, a village in Leicester).