Complex sentence: It is thought that this lifesaving measure is of more benefit than any risk of an antibody-mediated transfusion reaction; the risk of a serious transfusion reaction can be minimized if the donor unit is both ABO-compatible and Rhesus (Rh)-compatible.
Split into simpler sentences: It is thought that this lifesaving measure is of more benefit than any risk of an antibody-mediated transfusion reaction. In addition, the risk of a serious transfusion reaction can be minimized if the donor unit is both ABO-compatible and Rhesus (Rh)-compatible.