Complex sentence: In order to overcome manufacturing difficulties a first-generation BsMAb, called trifunctional antibody, has been developed consisting of two heavy and two light chains, one each from two different antibodies.
Split into simpler sentences: In order to overcome manufacturing difficulties, a first-generation BsMAb, called trifunctional antibody, has been developed. It consists of two heavy and two light chains, one each from two different antibodies.