Complex sentence: John and Mary Bolling's descendants are the only American descendants of Pocahontas, and include Edith Bolling Wilson, wife of U. S. President Woodrow Wilson and many of the First Families of Virginia.
Split into simpler sentences: John and Mary Bolling's descendants are the only American descendants of Pocahontas. They include Edith Bolling Wilson, wife of U. S. President Woodrow Wilson and many of the First Families of Virginia.