Complex sentence: His research in the 1990s at the University of California, Berkeley, led to the clinical development of ipilimumab (Yervoy ™), which was approved in 2011 by the FDA for the treatment of metastatic melanoma.
Split into simpler sentences: His research in the 1990s at the University of California, Berkeley,. This work ultimately led to the clinical development of ipilimumab (Yervoy ™), which was approved in 2011 by the FDA for the treatment of metastatic melanoma.