Complex sentence: The rough endoplasmic reticulum is especially prominent in cells such as hepatocytes whereas active smooth endoplasmic reticulum lacks ribosomes and functions in lipid metabolism, carbohydrate metabolism, and detoxification and is especially abundant in mammalian liver and gonad cells.
Split into simpler sentences: The rough endoplasmic reticulum is especially prominent in cells such as hepatocytes. The smooth ER is especially abundant in mammalian liver and gonad cells.