Complex sentence: The protohistoric period of the US state of West Virginia began in the mid 16th century with the arrival of European trade goods originating with explorers and colonists on the eastern and southern coasts and being brought inland by native trade routes.
Split into simpler sentences: The protohistoric period of the United States' state of West Virginia began in the mid-sixteenth century with the arrival of European trade goods. Explorers and colonists brought these goods to the eastern and southern costs of North America and were brought inland by native trade routes.