Complex sentence: A correct left ventricle filling is essential to maintain a proper cardiac output and it depends from ventricular relaxation and compliance, mitral valve area, atrio-ventricular gradient, atrial contraction and end-systolic volume.
Split into simpler sentences: A correct left ventricular filling is essential to maintain a proper cardiac output. Left ventricular filling is dependent upon ventricular relaxation and compliance, mitral valve area, atrio-ventricular gradient, atrial contraction and end-systolic volume.