Complex sentence: In Slovakia and Dominican Republic the disease is much more common, with prevalence estimated at 1:19,000 people; this is not the result of a single mutation but due to a group of 12 mutations in specific "hot spots" of the "HGD" gene.
Split into simpler sentences: In Slovakia and the Dominican Republic the disease is much more common, with prevalence estimated at 1:19,000 people. As for Slovakia, this is not the result of a single mutation but due to a group of 12 mutations in specific "hot spots" of the "HGD" gene.