Complex sentence: Octreotide may be used in conjugation with midodrine to cause periphreal vasoconstriction in the hepato-renal syndrome, in an effort to increase SVR, improve renal perfusion and prolong survival until definitive treatment with liver transplant.
Split into simpler sentences: Octreotide may be used in conjunction with midodrine to partially reverse periphreal vasodilation in the hepato-renal syndrome. By increasing systemic vascular resistance, these drugs reduce shunting and improve renal perfusion, prolonging survival until definitive treatment with liver transplant.