Complex sentence: After defeating the Broncos and the Chiefs in the first two rounds, the Colts lost to the New England Patriots in the title game, which saw the first playoff meeting between Tom Brady and Peyton Manning.
Split into simpler sentences: After defeating the Broncos and the Chiefs in the first two rounds, the Colts were unable to stop the New England Patriots in the title game. The game was the first playoff meeting between Tom Brady and Peyton Manning.