Complex sentence: The effect of amikacin is increased when used with drugs derived from the botulinum toxin, anesthetics, neuromuscular blocking agents, or large doses of blood that contains citrate as an anticoagulant.
Split into simpler sentences: The effect of amikacin is increased when used with drugs derived from the botulinum toxin. When used with anesthetics, neuromuscular blocking agents, or large doses of blood that contains citrate as an anticoagulant.