Complex sentence: James Bay is important in the history of Canada as one of the most hospitable parts of the Hudson Bay region (despite its low human population), and as a result its corresponding importance to the Hudson's Bay Company and British expansion into Canada.
Split into simpler sentences: James Bay is important in the history of Canada as one of the most hospitable parts of the Hudson Bay region despite its low human population. As a result, its corresponding importance to the Hudson's Bay Company and British expansion into Canada.