Complex sentence: He claimed that the world was now reaching a point in its history which echoed the past, and that total annihilation was again possible if humanity failed alter its negative pattern by "manipulating Karma" through service.
Split into simpler sentences: He claimed that the world was now reaching a point in its history which echoed the past, and that total annihilation was again possible. But that humanity could alter its negative pattern by "manipulating Karma" through service.