Complex sentence: Recent studies have shown that in patients suffering from acute coronary syndrome, high-dose statin treatment may play a plaque-stabilizing role with anti-inflammatory effects, by inciting reduction of the necrotic plaque core, and by improving endothelial function.
Split into simpler sentences: Recent studies have shown that in patients suffering from acute coronary syndrome, high-dose statin treatment may play a plaque-stabilizing role. At high doses, statins have anti-inflammatory effects, incite reduction of the necrotic plaque core, and by improve endothelial function.