Complex sentence: The major enzymatic functions carried out at the replication fork are well conserved from prokaryotes to eukaryotes, but the replication machinery in eukaryotic DNA replication is a massive complex coordinating many proteins all working at the site of replication, forming the replisome.
Split into simpler sentences: The major enzymatic functions carried out at the replication fork are well conserved from prokaryotes to eukaryotes. But the replication machinery in eukaryotic DNA replication is a massive complex coordinating many proteins all working at the site of replication, forming the replisome.