Complex sentence: Unfortunately this is untrue in NANPA member nations, and doubly untrue in the U.S. So a global title with CC of 1 can indicate any of 7 U.S. MCCs, or Canada, or any Caribbean nation.
Split into simpler sentences: Unfortunately this is untrue in NANPA member nations, and doubly untrue in the US. So, a global title with CC of 1 can indicate any of 7 US MCCs, or Canada, or any Caribbean nation.