Complex sentence: Hepatic involvement in RA may be essentially asymptomatic, however, recent research shows that for females, high serum cholesterol may be related to disease, and treatment with methotrexate may create silent liver fibrosis in patients with RA.
Split into simpler sentences: Hepatic involvement in RA may be essentially asymptomatic, however, recent research shows that for females, high serum cholesterol may be related to disease. However, treatment with methotrexate may create silent liver fibrosis in patients with RA.