Complex sentence: In 1850 she advocated in "The Occident," over the signature "A Daughter of Israel," the foundation of a Jewish Foster Home, and her advocacy was largely instrumental in the establishment of such a home in 1855.
Split into simpler sentences: In 1850 she advocated in The "Occident", over the signature "A Daughter of Israel", for the foundation of a Jewish foster home. Her advocacy was largely instrumental in the establishment of such a home in 1855.