Complex sentence: Moore's first major film role was in 2004's', followed by roles in "Grandma's Boy" and as a jaded art student in Terry Zwigoff's "Art School Confidential" (both 2006).
Split into simpler sentences: Moore's first major film role was in 2004's'. This was followed by roles in the films "Grandma's Boy", and as a jaded art student in Terry Zwigoff's "Art School Confidential" (both 2006).