Complex sentence: In 1446, it was used as the therapeutic drug in combination with alum to treat ulcers, and in 1623, it was used as an antiseptic and a mouthwash.
Split into simpler sentences: In 1446, it was used as a therapeutic drug, in combination with alum, to treat ulcers. And in 1623, it was used as an antiseptic and a mouthwash.