Complex sentence: In early 1923 when Roethke was 14 years old, his uncle committed suicide and his father died of cancer, and these events no doubt impacted him deeply and influenced his work.
Split into simpler sentences: In early 1923 when Roethke was 14 years old, his uncle committed suicide and his father died of cancer. Roethke noted that and these events impacted him deeply and influenced his work.