Complex sentence: Her father was the eldest son of Abu Sa'id Mirza, the Emperor of the Timurid Empire, while her paternal uncle was Umar Sheikh Mirza, the ruler of Ferghana Valley, who later became her father-in-law as well.
Split into simpler sentences: Her father was the eldest son of Abu Sa'id Mirza, the Emperor of the Timurid Empire. Aisha's paternal uncles included Umar Sheikh Mirza, the ruler of Ferghana Valley, who later became her father-in-law as well.