Complex sentence: The past generations of F-Zero had "piloted their way to fame", so it is the only "F-Zero" game without Captain Falcon, Samurai Goroh, Pico, or Dr. Stewart.
Split into simpler sentences: The past generations of F-Zero pilots "piloted their way to fame". Due to the aforementioned, it is the only "F-Zero" game without Captain Falcon, Samurai Goroh, Pico, or Dr. Stewart.