Complex sentence: In 1989 Dr. Vilcek and colleague, Junming Le, Ph.D, created a monoclonal antibody against TNF alpha, a powerful promoter of inflammation, and which is involved in the pathogenesis of numerous autoimmune diseases.
Split into simpler sentences: In 1989 Dr. Vilcek and colleague, Junming Le, Ph.D, created a monoclonal antibody against TNF alpha, a powerful promoter of inflammation. TNF-alpha is involved in the pathogenesis of numerous autoimmune diseases.