Complex sentence: Geographically isolated from the rest of the Greek world and much closer to the center of the Persian empire, Cyprus was the first to be crushed, and siege was subsequently laid to most of the other cities along the Ionian coast.
Split into simpler sentences: Geographically isolated from the rest of the Greek world and much closer to the center of the Persian empire, Cyprus was the first to be crushed. Siege was subsequently laid to most of the other cities along the Ionian coast.