Complex sentence: The complex became known as the Waldorf-Astoria Hotel, coincidentally becoming the host location to the U.S. inquiries into the sinking of the RMS "Titanic", on which Colonel Astor died.
Split into simpler sentences: The complex became known as the Waldorf-Astoria Hotel. The Waldorf-Astoria would later be the host location to the U.S. inquiries into the sinking of the RMS "Titanic", on which Astor died.