Complex sentence: The exact mechanism by which S100A8 and S100A9 is secreted during inflammation remains unknown, however it is known that translocation of the proteins to the plasma membrane and intermediate filaments occurs following rise in intracellular Ca 2 +.
Split into simpler sentences: The exact mechanism by which S100A8 and S100A9 is secreted during inflammation remains unknown. It is known that translocation of the proteins to the plasma membrane and intermediate filaments occurs following rise in intracellular Ca 2 +.