Complex sentence: When the last Christian stronghold in the Holy Land fell after the Siege of Acre in 1291, the order settled first in Cyprus and then, in 1310, led by Grand Master Fra' Foulques de Villaret, on the island of Rhodes.
Split into simpler sentences: When the last Christian stronghold in the Holy Land fell after the Siege of Acre in 1291, the order settled first in Cyprus. In 1310, led by Grand Master Fra' Foulques de Villaret, it regrouped on the island of Rhodes.