Complex sentence: Many cases of appendicitis require removal of the inflamed appendix by laparotomy or laparoscopy due to the high mortality associated with rupture of the appendix, which may lead to severe complications such as inflammation of the inner lining of the abdominal wall and sepsis.
Split into simpler sentences: Many cases of appendicitis require removal of the inflamed appendix by laparotomy or laparoscopy due to the high morbidity and mortality associated with rupture of the appendix. Sever complications of a ruptured appendix include inflammation of the inner lining of the abdominal wall and sepsis.