Complex sentence: The University of Chicago (U of C, Chicago, or UChicago) is a private research university in Chicago, Illinois and one of the world's leading and influential institutions of higher learning, with top ten positions in numerous rankings and measures.
Split into simpler sentences: The University of Chicago (U of C, Chicago, or UChicago) is a private research university in Chicago, Illinois. It is one of the world's leading and influential institutions of higher learning, with top ten positions in numerous rankings and measures.