Complex sentence: A 2005 study investigating the mode of action of artemisinin using a yeast model demonstrated the drug acts on the electron transport chain, generates local reactive oxygen species, and causes the depolarization of the mitochondrial membrane.
Split into simpler sentences: A 2005 study investigating the mode of action of artemisinin using a yeast model demonstrated the drug acts on the mitochondria. It is suggested that the electron transport chain activates artemisinin, generates local reactive oxygen species, and causes the depolarization of the mitochondrial membrane.