Complex sentence: This has been suggested as a mechanism in the conformational changes of amyloid beta and related amyloidogenic peptides implicated in protein misfolding diseases such as Alzheimer's disease, which may pass through an alpha-sheet intermediate in forming the beta-sheet-rich amyloid fiber assembly.
Split into simpler sentences: This has been suggested as a mechanism in the conformational changes of amyloid beta and related amyloidogenic peptides implicated in protein misfolding diseases such as Alzheimer's disease. These peptides may pass through an alpha-sheet intermediate in forming the beta-sheet-rich amyloid fiber assembly.