Complex sentence: On Opening Day 2012, Arencibia hit a game-winning 3-run home run in the 16th inning against the Cleveland Indians, the longest game in Opening Day history in terms of innings.
Split into simpler sentences: On Opening Day 2012, Arencibia hit a game-winning 3-run home run in the 16th inning against the Cleveland Indians. It was the longest game in Opening Day history in terms of innings.