Complex sentence: After his debut, Guido and Tonio travel to Rome for his premiere opera, where he gains the patronage of a powerful cardinal, Calvino, and befriends a powerful count from Florence, di Stefano.
Split into simpler sentences: After his debut, Guido and Tonio travel to Rome for his operatic premiere. There he gains the patronage of a powerful cardinal, Calvino, and befriends a powerful count from Florence, di Stefano.