Complex sentence: PBP2A has a low affinity for beta-lactams such as Methicillin, Penicillin, and this enables transpeptidase activity in the presence of beta-lactams to allow cell wall synthesis.
Split into simpler sentences: PBP2A has a low affinity for beta-lactams such as methicillin and penicillin. This enables transpeptidase activity in the presence of beta-lactams to allow cell wall synthesis.