Complex sentence: His brother, Francis Cabot Lowell was the founder of U.S. cotton manufacturing, and his other brother, Charles Lowell, was for many years the minister at the West End Church in Boston, and was the father of the famed poet James Russell Lowell.
Split into simpler sentences: His brother, Francis Cabot Lowell was the founder of U.S. cotton manufacturing. Lowell's other brother, Charles Lowell, was for many years the minister at the West End Church in Boston, and was the father of the famed poet James Russell Lowell.