Complex sentence: CLK is hyperphosphorylated when DOUBLE-TIME (DBT) kinase enters the CLK-CYC complex in a PER reliant manner, destabilizing both CLK and PER, leading to the degradation of both proteins.
Split into simpler sentences: CLK is hyperphosphorylated when DOUBLE-TIME (DBT) kinase enters the CLK-CYC complex in a PER dependent manner. This process destabilized both CLK and PER, leading to the degradation of both proteins.