Complex sentence: Specifically, α 1 receptors are characterized as G q GPCRs, signaling through Phospholipase C to increase IP 3 and DAG, thus increasing the release of calcium, and α 2 receptors are labeled as G i GPCRs, which signal through Adenylyl Cyclase to decrease cAMP.
Split into simpler sentences: Specifically, α 1 receptors are characterized as G q GPCRs, signaling through Phospholipase C to increase IP 3 and DAG, thus increasing the release of calcium. Meanwhile, α 2 receptors are labeled as G i GPCRs, which signal through Adenylyl Cyclase to decrease cAMP.