Complex sentence: Brodie managed to get an aromatase inhibitor into a limited clinical trial in breast cancer patients in London, which had such a profound effect that it led to Novartis-sponsored trials, the development of formestane, the first aromatase inhibitor, eventually marketed in 1994.
Split into simpler sentences: Brodie managed to get an aromatase inhibitor into a limited clinical trial in London, which had such a profound effect that it led to Novartis-sponsored trials. She was behind the development of formestane, the first aromatase inhibitor used on breast cancer patients, marketed in 1994.