Complex sentence: Holman took an interest in one particular fan, Zachary Smith Reynolds, the heir to R. J. Reynolds's tobacco company, was smitten from the start, despite their seven-year age difference.
Split into simpler sentences: Holman took an interest in one particular fan, Zachary Smith Reynolds, the heir to R. J. Reynolds's tobacco company. He was smitten from the start, despite their seven-year age difference.