Complex sentence: In pre-Hispanic Mexico, and generally throughout Mesoamerica, there was not any animal capable of being used in the loading and transport of goods and had to use man, this is how the "tameme" emerged.
Split into simpler sentences: In pre-Hispanic Mexico, and generally throughout Mesoamerica, there was not any animal capable of being used in the loading and transport of goods. Because of this, they had to use man; this is how the "tameme" emerged.