Complex sentence: Being unaware of the existence of vampires, the world considers Blade to be a serial killer--the vampires capitalize on this misconception and succeed in framing Blade (Wesley Snipes) for the killing of a familiar posing as a vampire.
Split into simpler sentences: Being unaware of the existence of vampires, the world considers Blade to be a serial killer. The vampires capitalize on this misconception and succeed in framing Blade (Wesley Snipes) for the killing of a familiar posing as a vampire.