Complex sentence: He was unusual interested in trachoma--a diseases prevalent in Malta at the time--in his early years, however he obtained his greatest reputation internationally for his treatment of glaucoma which was first published in 1924.
Split into simpler sentences: He was unusual interested in trachoma--a diseases prevalent in Malta at the time. In his early years, however he obtained his greatest reputation internationally for his treatment of glaucoma which was first published in 1924.