Complex sentence: In 2006, the Vradenburgs established the USAgainstAlzheimer's Political Action Committee, and in 2010, they established USAgainstAlzheimer's (USA2), an independent non-profit organization whose mission is to stop Alzheimer's disease by 2020.
Split into simpler sentences: In 2006, the Vradenburgs established the USAgainstAlzheimer's Political Action Committee. And in 2010, they established USAgainstAlzheimer's (USA2), an independent non-profit organization whose mission is to stop Alzheimer's disease by 2020.