Complex sentence: Susan Delfino tries to welcome Lee and his partner Bob to Wisteria Lane, but makes quite a mess of greeting them and ends up getting off on the wrong foot as Lee responds to her quite rudely.
Split into simpler sentences: Susan Delfino tries to welcome Lee and his partner, Bob, to Wisteria Lane. However, she makes quite a mess of greeting them and ends up getting off on the wrong foot, as Lee responds to her quite rudely.