Complex sentence: In exploratory studies, prolonged-release melatonin has shown sleep quality improvement in patients with schizophrenia as well as in patients with major depressive disorder and treating sleep-wake cycle disorders in children with underlying neurodevelopment difficulties.
Split into simpler sentences: In exploratory studies, prolonged-release melatonin has shown sleep quality improvement in patients with schizophrenia as well as in patients with major depressive disorder. It has shown promise in treating sleep-wake cycle disorders in children with underlying neurodevelopment difficulties.