Complex sentence: It has been proposed as a technique for changing wild populations, for instance to combat insects that spread diseases (in particular mosquitoes in the cases of malaria and zika), to control invasive species, or to eliminate herbicide-or pesticide resistance.
Split into simpler sentences: It has been proposed as a technique for changing wild populations of harmful organisms such as mosquitoes to be less dangerous. In addition to combating diseases spread by insects, gene drives might be used to control invasive species or to eliminate herbicide-or pesticide resistance.