Complex sentence: After it was issued, however, Elizabeth began the persecution of Catholics, leading to various conspiracies to assassinate her, starting with the Ridolfi plot later in 1570.
Split into simpler sentences: After it was issued, however, Elizabeth chose not to continue her policy of religious toleration. She instead began the persecution of her religious enemies, leading to various conspiracies to assassinate her, starting with the Ridolfi plot later in 1570.