Complex sentence: Sertraline is the second most potent inhibitor of 5-HT re-uptake which has two very interesting characteristics that distinguish it i.e. sertralines (1) inhibiting effect on DAT and NET and (2) the binding to σ-1 receptor in CNS.
Split into simpler sentences: Sertraline is the second most potent inhibitor of 5-HT re-uptake. Sertaline has two very interesting characteristics that distinguish it i.e. (1) inhibiting effect on DAT and NET and (2) the binding to sigma-1 receptor in CNS.