Complex sentence: It binds to the aconitase but cannot be released, irreversibly binding the aconitase causing disruption to the Krebs cycle, leading to a severe inhibition of cellular respiration.
Split into simpler sentences: It binds to the aconitase but cannot be released, irreversibly binding the aconitase. This causes disruption to the Krebs cycle, leading to a severe inhibition of cellular respiration.