Complex sentence: In cases where long-term ventilator dependence may be required, the patient-end of the circuit will normally be connected to a tracheotomy canula, which is much more comfortable and practical for long-term care than is larynx or nasal intubation.
Split into simpler sentences: In cases where long-term ventilator dependence may be required, the patient-end of the circuit may be either noninvasive or invasive. Invasive methods employ some sort of intubation, which for long-term use will normally be a tracheotomy canula, which is much more comfortable and practical for long-term care than is larynx or nasal intubation.