Complex sentence: Blocking the potassium channels on the membranes of these cells effectively reduces the membrane potential which in turn leads to voltage gated calcium channels being opened and neurotransmitter release which begins the process of relaying the signal to the central nervous system.
Split into simpler sentences: Blocking the potassium channels on the membranes of these cells effectively depolarizes the membrane potential, which in turn leads to opening of voltage gated calcium channels and neurotransmitter release. This begins the process of relaying the signal to the central nervous system.