Complex sentence: Hughes returned to Salt Lake City, Utah opened an office in a new wing of her older home built by her step-father soon after she was called by Mormon church leaders to become the 2nd resident physician for the newly founded Deseret Hospital in 1882.
Split into simpler sentences: Hughes returned to Salt Lake City, Utah and opened a private practice in a new wing of her old home built by her step-father. Soon after, she was called by Mormon church leaders to become the resident physician for the newly founded Deseret Hospital in 1882.