Complex sentence: It is South Florida's main airport for long-haul international flights and a hub for the Southeastern United States, with passenger and cargo flights to cities throughout the Americas, Europe and Western Asia, as well as cargo flights to East Asia.
Split into simpler sentences: It is South Florida's main airport for long-haul international flights and a hub for the Southeastern United States. Miami International Airport has passenger and cargo flights to cities throughout the Americas, Europe and Western Asia, as well as cargo flights to East Asia.