Complex sentence: Speakon connectors are designed to be unambiguous in their use in speaker cables; with jack and XLR connections, it is possible to use low-current shielded microphone or instrument cables in a high-current speaker application.
Split into simpler sentences: Speakon connectors are designed to be unambiguous in their use in speaker cables. However, with jack and XLR connections, it is possible to use low-current shielded microphone or instrument cables in a high-current speaker application.