Complex sentence: Neely went off to San Francisco, annoying her manager, Lyon Burke (Paul Burke) and then she began to try to break up the relationship he had with her friend, Anne, which drove her to the dolls as well.
Split into simpler sentences: Neely went off to San Francisco, annoying her manager, Lyon Burke (Paul Burke). She also tried to break up his relationship with her friend Anne, which drove her to the dolls as well.