Complex sentence: The city is located in the state's south-east on the estuary of the Derwent River, making it the most southern of Australia's capital cities and its harbour forms the second-deepest natural port in the world.
Split into simpler sentences: The city is located in the state's south-east on the estuary of the Derwent River, making it the most southern of Australia's capital cities. Its harbour forms the second-deepest natural port in the world.