Complex sentence: Two years later, he again travelled to Buenos Aires; but it proved to be his last trans-Atlantic excursion, and he never appeared in North America, despite overtures for the management of the New York Metropolitan Opera.
Split into simpler sentences: Two years later, he again travelled to Buenos Aires but it proved to be his last trans-atlantic excursion. Consequently, he never appeared in North America, despite overtures for the management of the New York Metropolitan Opera.