Complex sentence: The Tuscarora had actually emigrated from the region now known as Western New York to the region now known as Eastern Carolina prior to the arrival of Europeans in North America, but had their first encounter with Europeans in North Carolina and Virginia.
Split into simpler sentences: The Tuscarora had emigrated from the region now known as Western New York to the region now known as Eastern Carolina prior to the arrival of Europeans in North America. They had their first encounter with Europeans in North Carolina and Virginia.