Complex sentence: After being bound onto its purinergic receptor, adenosine results in a negative chronotropic effect by acting on cardiac pacemakers and causes a negative dromotropic effect through the inhibition of AV-nodal conduction.
Split into simpler sentences: After being bound onto its purinergic receptor, adenosine results in a negative chronotropic effect by acting on cardiac pacemakers. It also causes a negative dromotropic effect through the inhibition of AV-nodal conduction.