Complex sentence: The ministers did not appreciate Cixi's interference in political matters, and the frequent confrontations left the Empress Dowager Ci'an in a frustrated state, to the point where she refused to come to court audiences, leaving Empress Dowager Cixi to deal with the ministers alone.
Split into simpler sentences: The ministers did not appreciate Cixi's interference in political affairs, and the frequent confrontations left the Empress Dowager Ci'an frustrated. Ci'an often refused to come to court audiences, leaving Empress Dowager Cixi to deal with the ministers alone.