Complex sentence: Other than a prior history of PML, there are no reliable methods for identifying patients that are more likely to develop this complication; consequently, natalizumab is contraindicated for individuals who have had PML or at risk for it due to immunosuppression.
Split into simpler sentences: Other than a prior history of PML, there are no reliable methods for identifying patients that are more likely to develop this complication. Consequently, natalizumab is contraindicated for individuals who have had PML or at risk for it due to immunosuppression.