Complex sentence: The largest nearby locality is Lázaro Cardenas, home to 16,294 people in 2010 census, the whole area (6 localities) housing roughly 25,000 people, up from 20,000 in 2000, the largest population cluster south of Ensenada within the state.
Split into simpler sentences: The largest nearby locality is Lázaro Cardenas, home to 16,294 people as of the 2010 census. This is the largest population cluster south of Ensenada within the state.