Complex sentence: Sources indicate that he was born in Carlisle, England, however he may have been born in or near Workington, England, he emigrated with his parents and siblings to Charles Town, Virginia (now West Virginia), where he opened a medical practice.
Split into simpler sentences: Sources indicate that he was born in Carlisle, England; however he may have been born in or near Workington, England. He emigrated with his parents and siblings to Charles Town, Virginia (now West Virginia), where he opened a medical practice.