Complex sentence: Initially, Van and Irvine are enemies because of Irvine's desire to take Zeke, but end up traveling together when they meet with traveler Moonbay, with Van having to stay with Moonbay because she blew up her cargo to help him.
Split into simpler sentences: Initially, Van and Irvine are enemies because of Irvine's attempts to steal Zeke, but they end up traveling together when they meet Moonbay. Van has to travel with Moonbay because she blew up her cargo to help him.