Complex sentence: Difficulties with Native American tribes and with British trading outposts presented continuing obstacles for American expansion until military campaigns of General "Mad" Anthony Wayne against the Native Americans culminated with victory at the Battle of Fallen Timbers in 1794 and the Treaty of Greenville of 1795.
Split into simpler sentences: Difficulties with Native American tribes and with British trading outposts presented continuing obstacles for American expansion. Finally, however, the military campaign of General "Mad" Anthony Wayne against the Native Americans culminated with victory at the Battle of Fallen Timbers in 1794 and the Treaty of Greenville of 1795.