Complex sentence: He had four children, Quina, Bruno, Caio, and Isabel with Elizabeth Kaplan, two of whom (Bruno Fonseca and Caio Fonseca) became renowned artists.
Split into simpler sentences: He had four children, Quina, Bruno, Caio, and Isabel with Elizabeth Kaplan. Two of whom (Bruno Fonseca and Caio Fonseca) became renowned artists.