Complex sentence: The telomeric repeat-binding factor 1 is a component of the shelterin nucleoprotein complex, which is known to protect telomeres in mammals from DNA mechanisms that are used for repair purposes and at the same time regulate the activity carried out by telomerase.
Split into simpler sentences: The telomeric repeat-binding factor 1 is a component of the shelterin nucleoprotein complex. Which is known to protect telomeres in mammals from DNA mechanisms that are used for repair purposes and at the same time regulate the activity carried out by telomerase.