Complex sentence: Long-term consumption of fructose in rats has been shown to increase levels of triglycerides and trigger leptin and insulin resistance,, however, another study found that leptin resistance only developed in the presence of both high fructose and high fat levels in the diet.
Split into simpler sentences: Long-term consumption of fructose in rats has been shown to increase levels of triglycerides and trigger leptin and insulin resistance. However, another study found that leptin resistance only developed in the presence of both high fructose and high fat levels in the diet.