Complex sentence: Lisa's existential anxiety puzzles Homer's simple emotional sensibilities, and Marge attempts to administer the advice "she" was given by her mother regarding happiness, but nothing her parents say can bring Lisa out of her depression.
Split into simpler sentences: Lisa's existential anxiety puzzles Homer's simple emotional sensibilities, and Marge attempts to administer the advice "she" was given by her mother regarding happiness. Nothing her parents say can bring Lisa out of her depression.