Complex sentence: When the Yamassee, also called "The First Peoples" of the Western Hemisphere, could not or would not accommodate the conquerors and settlers, they were tortured, some were killed, and many tribal members were forced into becoming "Negro" slaves.
Split into simpler sentences: When the yamassee, also called "The First Peoples" of the Western Hemisphere, could not or would not accommodate the conquerors and settlers the yamassee people were tortured and killed. Many family and tribal members were forced into becoming "Negro" slaves.