Complex sentence: He sued for help by all the powers of the time, France and Holy Roman Empire included, but in vain, and could return in Pesaro only after the death of Alexander VI and the illness of Cesare Borgia (1503).
Split into simpler sentences: He sued for help to all the major powers of the time--including France and Holy Roman Empire--but in vain. Giovanni Sforza could return to Pesaro only after the death of Alexander VI and the illness of Cesare Borgia (1503).