Complex sentence: She is best known for her role as Sarah-Louise Platt in the ITV soap "Coronation Street" from 1999 to 2007 and 2015 onwards and her role as Bex Fisher in the BBC school drama "Waterloo Road" from 2010 to 2011.
Split into simpler sentences: She is best known for her role as Sarah-Louise Platt in the ITV soap "Coronation Street". O'Brien also played Bex Fisher in the BBC school drama "Waterloo Road" from 2010 to 2011.