Complex sentence: The City of Waterdeep, an integral part of Ed Greenwood's house campaign, is situated on the Sword Coast, and with a population of over 100,000, is the most important city in the north of the Forgotten Realms setting.
Split into simpler sentences: The city of Waterdeep, an integral part of Ed Greenwood's house campaign, is situated on the Sword Coast. With a population of over 100,000, it is the most important city in the north of the Forgotten Realms setting.