Complex sentence: Perhaps the biggest highlight of Uecker's career was when he hit a home run off future Hall of Famer Sandy Koufax after which Uecker joked that he always thought that home run would keep Koufax from getting into the Hall of Fame.
Split into simpler sentences: Perhaps the biggest highlight of Uecker's career was when he hit a home run off of future Hall-of-Famer Sandy Koufax. Uecker has joked that he always thought that home run would keep Koufax from getting into the Hall of Fame.