Complex sentence: At the age of five Joseph left Avignon with his father and went to Genoa, where they remained until 1516; driven from that city, they went to Novi, but returned to Genoa in 1538, where Joseph practised medicine for twelve years.
Split into simpler sentences: At the age of five Joseph left Avignon with his father and went to Genoa, where they remained until 1516. Driven from that city, they went to Novi, but returned to Genoa in 1538, where Joseph practiced medicine for twelve years.