Complex sentence: Tremelimumab (formerly ticilimumab, CP-675,206) is a fully human monoclonal antibody against CTLA-4, produced by Pfizer, undergoing human trials for the treatment of cancer.
Split into simpler sentences: Tremelimumab (formerly ticilimumab, CP-675,206) is a fully human monoclonal antibody against CTLA-4. It has been undergoing human trials for the treatment of cancer.