Complex sentence: He was called up to the majors for the first time on September 6,2011, and made his major league debut on September 7,2011, pitching 1 1/3 scoreless innings against the Houston Astros.
Split into simpler sentences: He was called up to the majors for the first time on September 6,2011. Hughes made his major league debut on September 7,2011, pitching 1 1/3 scoreless innings against the Houston Astros.