Complex sentence: The top-down technique or high-energy techniques require formation of cubosomes prior to their use in a product is used whereby bulk cubic phase is first produced and then dispersed by high energy processing into cubosome nanoparticles.
Split into simpler sentences: The top-down technique or high-energy techniques require formation of cubosomes prior to their use in a product. It is used whereby bulk cubic phase is first produced and then dispersed by high energy processing into cubosome nanoparticles.