Complex sentence: Tucson was an isolated community during its earliest years, situated on the right side of the Santa Cruz River, next to a Pima pueblo, known as Indian Town, on the left side of the water, roughly northwest of Tucson.
Split into simpler sentences: Tucson was an isolated community during its earliest years, situated on the right side of the Santa Cruz River. Also next to a Pima pueblo, known as Indian Town, on the left side of the water, roughly northwest of Tucson.