Complex sentence: Premature trypsin activation can be destructive and may trigger a series of events that lead to pancreatic self-digestion, and around 5% of trypsinogens are thought to get activated in pancreas, there are therefore a number of defenses against such inappropriate activation in cells.
Split into simpler sentences: Premature trypsin activation can be destructive and may trigger a series of events that lead to pancreatic self-digestion, and around 5% of trypsinogens are thought to get activated in pancreas. There are therefore a number of defenses against such inappropriate activation in cells.