Complex sentence: The North Cathedral was also erected at the top of Shandon Street in 1624, however, the present day structure is the fifth church to occupy the site, having been rebuilt numerous times, most recently following an 1820 fire.
Split into simpler sentences: The North Cathedral was also erected at the top of Shandon Street in 1624. The present day structure, however, is the fifth church to occupy the site; churches have been rebuilt there numerous times, most recently following an 1820 fire.