Complex sentence: The construction of a cell with a synthetic genome was done to test the methodology in order to allow more modified genomes to be created in future, consequently to minimise sources of failure the genome was created using a natural genome as a template.
Split into simpler sentences: The construction of a cell with a synthetic genome was done to test the methodology--allowing more modified genomes to be created in the future. To minimize sources of failure, the genome was created using a natural genome as a template.