Complex sentence: Orlando has hosted the New York City portions of the MDA Labor Day Telethon on WWOR-TV since the 1980s but quit in 2011 in response to Jerry Lewis' firing from the Muscular Dystrophy Association.
Split into simpler sentences: Orlando has hosted the New York City portions of the MDA Labor Day Telethon on WWOR-TV since the 1980s. He quit the show in 2011 in response to Jerry Lewis' firing from the Muscular Dystrophy Association.