Complex sentence: Great Missenden lay on a major route between the Midlands and London and several coaching inns, particularly the Red Lion (now an estate agency) and The George (which still exists) provided rest and refreshment for travellers and their horses.
Split into simpler sentences: Great Missenden lay on a major route between the Midlands and London. Several coaching inns, particularly the Red Lion (now an estate agency) and The George (which still exists), provided rest and refreshment for travellers and their horses.