Complex sentence: In her effort to promote Roman Catholicism she ordered all copies of this book to be destroyed--despite having translated Erasmus' commentary on St. John, for which she is praised in this very book.
Split into simpler sentences: In her effort to promote Roman Catholicism she ordered all copies of this book to be destroyed. She did this despite her having translated Erasmus' commentary on St. John, for which she is praised in this very book.