Complex sentence: While a hilariously-comedic styling, the movie makes important comments on the social impact of obesity in contemporary America--and also highlights the genetic and endocrinological basis of the disease, in the context of the exacerbating effects of the American diet.
Split into simpler sentences: While a hilariously-comedic styling, the movie makes important comments on the social impact of obesity in contemporary America. It is also particularly notable in that it highlights the genetic and endocrinological basis of the disease, in the context of the exacerbating effects of the American diet.