Complex sentence: Even so, the detection of DNA fragmentation and the presence of single strand ends of DNA have continued to be used in many studies to detect apoptotic cells, particularly in intact tissues, though necrosis also produces single-strand DNA ends in cell nuclei.
Split into simpler sentences: Even so, the detection of DNA fragmentation and the presence of single strand ends of DNA has continued to be an assay used in many studies to detect apoptotic cells, particularly in intact tissues. This is in spite of the fact that necrosis also produces single-strand DNA ends in cell nuclei.