Complex sentence: In 1994, in the US, the average life expectancy of persons with this condition was estimated to be 42 years in males and 48 years in females, but today, thanks to better management of the disease, patients can live into their 70s or beyond.
Split into simpler sentences: In 1994, the average life expectancy of persons with this condition in the US was estimated to be 42 years in males and 48 years in females,. Thanks to improved management of the disease, patients can nowadays live into their 70s or beyond.