Complex sentence: TSC1 and TSC2 work in a complex together to inhibit activation of the kinase mTOR, loss of regulation of mTOR generates enlarged cells, abnormal differentiation, and abnormal development.
Split into simpler sentences: TSC1 and TSC2 work in a complex together to inhibit activation of the kinase mTOR. A loss of regulation of mTOR generates enlarged cells, abnormal differentiation, and abnormal development.