Complex sentence: Major depressive disorder affects approximately 253 million (3.6%) of people annually, although the percentage of people who are affected at one point in their life varies from 7% in Japan to 21% in France.
Split into simpler sentences: Major depressive disorder affects approximately 253 million (3.6%) of people annually. The percentage of people who are affected at one point in their life varies from 7% in Japan to 21% in France.