Complex sentence: Hence, diazirines have grown in popularity as small photo-reactive crosslinking reagents used in photoaffinity labeling studies to observe ligand-receptor, ligand-enzyme, protein-protein, and protein-nucleic acid interactions.
Split into simpler sentences: Hence, diazirines have grown in popularity as small photo-reactive crosslinking reagents. They are often used in photoaffinity labeling studies to observe a variety of interactions, including ligand-receptor, ligand-enzyme, protein-protein, and protein-nucleic acid interactions.