Complex sentence: Even if he is confirmed to be depowered, it is still unknown if his Shi-ar heritage will affect him as it did his sister, or if Sage's tampering of his bio-chemistry will have any negative effects in the future.
Split into simpler sentences: Even if he is confirmed to be depowered, it is still unknow if his Shi-ar heritage will affect him as well as it did his sister. OR if Sage's tampering of his bio-chemistry will have any negative effects in the future.