Complex sentence: The demand for education in the state grew, so that many students had to leave the entity to Mexico City for their studies and many of them stayed in that city to file for that reason the State lost with this important personalities.
Split into simpler sentences: The demand for education in the state grew, so that many students had to leave the entity to Mexico City for their studies. Many of them stayed in that city to file for that reason the State lost many important personalities.