Complex sentence: Studies on the use of carbamazepine in pregnant women have demonstrated exposure of the fetus to the drug and its metabolites to be teratogenic and is associated with the development of spina bifida, neurodevelopmental problems, craniofacial defects, cardiovascular malformations, hypospadias, and developmental delays.
Split into simpler sentences: Studies on the use of carbamazepine in pregnant women have demonstrated exposure of the fetus to the drug and its metabolites. Intrauterine exposure to carbamazepine has been shown to be teratogenic and is associated with the development of spina bifida, neurodevelopmental problems, craniofacial defects, cardiovascular malformations, hypospadias, and developmental delays.