Complex sentence: In addition, 63.2% of the city's population was of Hispanic or Latino origin, of any race; therefore, San Antonio, Texas has the largest Hispanic population of any city in the US with a Hispanic-majority population.
Split into simpler sentences: In addition, 63.2% of the city's population was of Hispanic or Latino origin, of any race. Moreover, San Antonio, Texas has the largest Hispanic population of any place in the US with a Hispanic majority population.