Complex sentence: He painted portraits of some of the greatest names of Portuguese society and culture of his time, like the poet Antero de Quental, in 1889, in his most famous portrait, that seems to anticipate Antero's suicide.
Split into simpler sentences: He painted portraits of some of the greatest names of Portuguese society and culture of his time, like the poet Antero de Quental in 1889. This, his most famous portrait, seems to anticipate Antero's suicide.