Complex sentence: Much of her work has started with a "YES, YOU CAN" premise: even though a child may appear incapable of doing or understanding something, if we pose the question differently or teach the concept in new ways, the child can succeed.
Split into simpler sentences: Much of her work has started with a "YES, YOU CAN" premise. That is, even though a child appears not to be able to do or understand something, if we only we ask the question in a different way or teach the concept in a different way, the child can succeed.