Complex sentence: Ephron was born in New York City, eldest of four daughters in a Jewish family, and grew up in Beverly Hills; her parents, Henry and Phoebe Ephron, were both East Coast-born and raised screenwriters.
Split into simpler sentences: Ephron was born in New York City, eldest of four daughters, in a Jewish family, and grew up in Beverly Hills. Her parents, Henry and Phoebe Ephron, were both East Coast-born and raised screenwriters.