Complex sentence: If the patient says he feels it in the Right Lower Quadrant then there may be an inflamed organ or piece of tissue in the Right Lower Quadrant... quite often the appendix, but other pathology can also give a "Positive" Rosving's sign.
Split into simpler sentences: If the patient feels it in the Right Lower Quadrant then there may be an inflamed organ or piece of tissue in the Right Lower Quadrant. The appendix is generally the prime suspect, although other pathology can also give a "Positive" Rosving's sign.