Complex sentence: DX-9065a has a selectivity for FXa compared to thrombin which has a glutamic acid in position 192 that causes electrostatic repulsion between the carboxyl group of DX-9065a.
Split into simpler sentences: DX-9065a has a selectivity for FXa. In comparison, thrombin has a glutamic acid in position 192 that causes electrostatic repulsion between the carboxyl group of DX-9065a.