Complex sentence: Hughes returned to Salt Lake City, Utah opened an office in a new wing of her older home built by her step-father before becoming the 2nd resident physician for the newly founded Deseret Hospital in 1882.
Split into simpler sentences: Hughes returned to Salt Lake City, Utah opened an office in a new wing of her older home built by her step-father. Before becoming the 2nd resident physician for the newly founded Deseret Hospital in 1882.