Complex sentence: Chromosome 4 pericentric inversion has been observed in 10 patients, with associated cardiac defects linked to terminal 4q35.1 deletions, which may affect "SORBS2".
Split into simpler sentences: Chromosome 4 pericentric inversion has been observed in 10 patients, and cardiac defects have been associated. These defects have been linked to terminal 4q35.1 deletions, which may affect "SORBS2".