Complex sentence: Mr. Milk is probably inspired by either Caspar Milquetoast, a comic book character remarkably similar to him, and he physically resembles South Park's Herbert Garrison, notable because Amy Winfrey worked on the first few episodes of South Park.
Split into simpler sentences: Mr. Milk is probably inspired by Caspar Milquetoast, a comic book character remarkably similar to him. He also physically resembles South Park's Herbert Garrison, notable because Amy Winfrey worked on the first few episodes of South Park.