Complex sentence: These machines were the first to spin cotton mechanically "without the intervention of human fingers", enabling them to be driven by a non-human power source, which in turn allowed the use of much larger machinery and made it possible to concentrate production into organised factories.
Split into simpler sentences: These machines were the first to spin cotton mechanically "without the intervention of human fingers". This enabled them to be driven by a non-human power source, which in turn allowed the use of much larger machinery and made it possible to concentrate production into organised factories.