Complex sentence: In the 1880s, the property passed into the hands of Hampton II's three daughters, who in turn sold it in 1890 to their niece Caroline and her new husband, Dr. William Halsted, a prominent surgeon.
Split into simpler sentences: In the 1880s, the property passed into the hands of Hampton II's three daughters. They sold it in 1890 to their niece Caroline Hampton and her new husband, Dr. William Halsted, a prominent surgeon.