Complex sentence: It also has usefulness in the treatment of cocaine-induced cardiovascular complications, where one would generally avoid Beta-blockers (e.g. metoprolol), as they can cause unopposed alpha-adrenergic mediated coronary vasoconstriction, worsening myocardial ischemia and hypertension.
Split into simpler sentences: It also has usefulness in the treatment of cocaine induced hypertension, where one would generally avoid beta blockers. They can cause an unopposed alpha-adrenergic mediated coronary vasoconstriction, worsening myocardial ischemia and hypertension.