Complex sentence: Brandt, whose patients included celebrities such as Madonna, was once referred to as the "Baron of Botox" and "King of Collagen," and had the distinction of using more of both than any other dermatologist in the world.
Split into simpler sentences: Brandt, whose patients included celebrities such as Madonna, was once referred to as the "Baron of Botox" and "King of Collagen". He was noted for using more of both than any other dermatologist in the world.