Complex sentence: Thus, it is very common for computational optimization programs to flip back and forth between representations during their iterations; this can dominate the calculation time of the potential itself and in long chain molecules introduce cumulative numerical inaccuracy.
Split into simpler sentences: Thus, it is very common for computational optimizing programs to flip back and forth between representations during their iterations. This can dominate the calculation time of the potential itself and in long chain molecules introduce cumulative numerical inaccuracy.