Complex sentence: Blockage of the arteries as a result of plaque buildup is also a cause of ischemia, the plaque builds up in an artery and blocks the flow of blood to the brain and lungs.
Split into simpler sentences: Blockage of the arteries as a result of plaque buildup is also a cause of ischemia. The plaque builds up in an artery and blocks the flow of blood to the brain and lungs.