Complex sentence: The altarpiece was commissioned for the Hospices de Beaune in 1443 by Nicolas Rolin, Chancellor of Burgundy, and his wife Guigone de Salins who was buried in the chapel, in front of the altarpiece's original positioning.
Split into simpler sentences: The altarpiece was commissioned for the Hospices de Beaune in 1443 by Nicolas Rolin, Chancellor of Burgundy, and his wife Guigone de Salins. De Salins was buried in the chapel, in front of the altarpiece's original positioning.