Complex sentence: It is in Rome at "16 Via degli Astalli" at the "Piazza del Gesù", and it replaced an older and smaller chapel of Saint Ignatius of Loyola dedicated to Our Lady of the Way.
Split into simpler sentences: It is in Rome, Italy at "16 Via degli Astalli" in the "Piazza del Gesù". The current structure replaced an older, smaller chapel of Saint Ignatius of Loyola dedicated to Our Lady of the Way.