Complex sentence: However, the drugs are more prominent, often tossed with wry souffrance--and social connections are rarely a savior in Effinger's world, but rather the cause of more painkillers, uppers, downers, and so on.
Split into simpler sentences: However, the drugs are more prominent, often tossed with wry "souffrance". Social connections are rarely a savior in Effinger's world, but rather the cause of more painkillers, uppers, downers, and so on.