Complex sentence: Perhaps one of the most prevalent occurrences of spontaneous mutation in the DNA is in depurination, which occurs when there is an interruption in the glycosidic bond between the base and deoxyribose.
Split into simpler sentences: Perhaps one of the most prevalent occurrences of spontaneous mutation in the DNA is in depurination. This is when there is an interruption in the glycosidic bond between the base and deoxyribose.