Complex sentence: Since the microtubules play an important role in the cell division especially in the G2/M phase of the cell cycle, attempts has been made to modulate the microtubule by binding the to tubulin and were successfully used in clinics.
Split into simpler sentences: Since the microtubules play an important role in the cell division especially in the G2/M phase of the cell cycle. Attempts has been made to modulate the microtubule by binding the to tubulin and were successfully used in clinics.