Complex sentence: His father, Yehuda, was a Talmudist and both parents were descendants of rabbinic families-his mother was the granddaughter of Rabbi Yehuda Loew, the Maharal of Prague.
Split into simpler sentences: His father, Yehuda, was a Talmudist; both parents were descendants of rabbinic families. On his mother's side, the Maharsha was the great-grandson of Rabbi Yehuda Loew, the Maharal of Prague.