Complex sentence: Isolation is frequently exacerbated by relocation away from family and friends, limited free time to relax or develop new support systems; psychosocial concerns, brought on by the stress of residency; and inadequate coping skills.
Split into simpler sentences: Isolation is frequently exacerbated by relocation away from family and friends. Other stressors include: limited free time to relax or develop new support systems; psychosocial concerns, brought on by the stress of residency; and inadequate coping skills.