Complex sentence: DQ2.5 binds gliadin, but the binding is sensitive to deamidation that is created by tissue transglutaminase, in almost all case the highest affinity sites of gluten are derived by deamidation.
Split into simpler sentences: DQ2.5 binds gliadin, but the binding is sensitive to deamidation caused by tissue transglutaminase. In almost all case the highest affinity sites of gluten are derived by deamidation.