Complex sentence: His work is concerned with the relationship between technology and culture, who is best known for his Nintendo game cartridge hacks and his subversive reworking of obsolete computer systems of the 70's and 80's.
Split into simpler sentences: His work is concerned with the relationship between technology and culture. Cory's best known projects probably are his Nintendo game cartridge hacks and his subversive reworking of obsolete computer systems of the 70's and 80's.