Complex sentence: The first European, Jacques Cartier, reached the site in 1535, however it was only in 1639 that the first permanent white settlement was established by Frenchman Jerome Le Royer, leading to the establishment of Ville Marie, a Roman Catholic mission, in 1642.
Split into simpler sentences: The first European, Jacques Cartier, reached the site in 1535. However, it was only in 1639 that the first permanent white settlement was established by Frenchman Jerome Le Royer, leading to the establishment of Ville Marie, a Roman Catholic mission, in 1642.