Complex sentence: West of I-290, Irving Park Road remains commercial, but with more national chain businesses (Holiday Inn, Subway, Truffles Grove etc.) The Itasca post office is also on this stretch.
Split into simpler sentences: West of I-290, Irving Park Road remains commercial, but with more national chain businesses (Holiday Inn, Subway, Truffles Grove etc.). Bread and Butter (Italian Restaurant) is The Itasca post office is also on this stretch.