Complex sentence: Around year 1000, the temple built in Tiber Island in the honor of Asclepius, Greek god of medicine, was replaced by a shelter for beggars, poor, and sick and was dedicated to Bartholomew the Apostle who was one of the Twelve Apostles of Jesus.
Split into simpler sentences: Around year 1000, the temple dedicated to Asclepius, Greek god of medicine, was built in Tiber Island which was later replaced by a shelter for beggars, poor, and sick. It was dedicated to Bartholomew the Apostle who was one of the Twelve Apostles of Jesus.