Complex sentence: In February 1844 he became curate of St. Mark's church, Kennington, London, and in April 1845 perpetual curate of St. Andrew-the-Less, a large parish in Cambridge where a portion of the population were of the most disreputable and degraded character.
Split into simpler sentences: In February 1844 he became curate of St. Mark's, Kennington, London, and in April 1845 perpetual curate of St. Andrew-the-Less. This was a large parish in Cambridge where a portion of the population were of the most disreputable and degraded character.