Complex sentence: The Tri-Cities area is located about 25 miles south of the Virginia's State Capital of Richmond, and is centered on the Appomattox River, which has its confluence with the James River near historic City Point in Hopewell.
Split into simpler sentences: The Tri-Cities area is centered on the Appomattox River about 25 miles south of Richmond. The Appomattox has its confluence with the James River near historic City Point in Hopewell.