Complex sentence: As the women return in a reprise of the Overture (Reprises), this time to let him go, only Luisa is absent, and Guido feels the aching void left by the only woman whom he will ever love.
Split into simpler sentences: As the women return in a reprise of the Overture (Reprises), but this time to let him go, only one is absent. And Guido feels the aching void left by the only woman he will ever love.