Complex sentence: The phenotypes of Finnish individuals with these LOF variants were then analyzed to ascertain novel genotype-phenotype associations including those one that could be embryonic lethal, information that would not have been discovered if researching with a phenotype-first approach.
Split into simpler sentences: The phenotypes of Finnish individuals with these LOF variants were then analyzed to ascertain novel genotype-phenotype associations. These associations detected included one that could be embryonic lethal, information that might not have been discovered in research using a phenotype-first approach.