Complex sentence: His second wife was Anne (1528-1610), daughter of Sir Anthony Cooke, by whom he had two sons, Anthony Bacon (1558-1601) and Francis Bacon.
Split into simpler sentences: His second wife was Anne (1528-1610), daughter of Sir Anthony Cooke, by whom he had two sons. His sons by his second wife were Anthony Bacon (1558-1601) and Francis Bacon.