Complex sentence: Commander Shepard engages in conversation with Harbinger at multiple points in Mass Effect 2, and is indirectly responsible for Commander Shepard's "death" at the hands of the Collectors.
Split into simpler sentences: Commander Shepard engages in conversation with Harbinger at multiple points in Mass Effect 2. Harbinger is indirectly responsible for Commander Shepard's "death" at the hands of the Collectors.