Complex sentence: Throughout her 53 years of marriage, Ruqaiya remained childless, but was given the primary responsibility for the upbringing of her grandson, prince Khurram (the future Emperor Shah Jahan).
Split into simpler sentences: Throughout her 53 years of marriage, Ruqaiya remained childless. However she was given the primary responsibility for the upbringing of her grandson, prince Khurram (the future Emperor Shah Jahan).