Complex sentence: Stephen Hopkins and his family, consisting of his wife Elizabeth and his children Constance, Giles and Damaris, departed Plymouth, England on the "Mayflower" on September 6/16,1620.
Split into simpler sentences: Stephen Hopkins and his family boarded the "Mayflower" consisting of his wife Elizabeth and his children Constance, Giles and Damaris. The "Mayflower" departed Plymouth, England on the "Mayflower" on September 6/16,1620.