Complex sentence: In Week 1 of the 2011 NFL season, Brady threw for 517 yards and 4 touchdowns, with one interception, against the Miami Dolphins, the second time he had thrown for 400 or more yards in a single game.
Split into simpler sentences: In Week 1 of the 2011 NFL season, Brady threw for 517 yards, 4 touchdowns, and one interception in a game against the Miami Dolphins. This was the second time that he had thrown for 400 or more yards in a single game.