Complex sentence: Direct Xa inhibitors are a class of relatively new oral anticoagulant drugs, by inhibiting the blood coagulation cascade at the final step they hinder factor Xa in splitting prothrombin into thrombin.
Split into simpler sentences: Direct Xa inhibitors are a class of relatively new oral anticoagulant drugs. They inhibit the blood coagulation cascade at the final step, hindering factor Xa in splitting prothrombin into thrombin.