Complex sentence: It runs from Oxford Street in the south to Marylebone High Street in the north, its winding shape following the course of the Tyburn stream that once ran alongside it and pre-dating the grid pattern of the other streets in the area.
Split into simpler sentences: It runs from Oxford Street in the south to Marylebone High Street in the north. Its winding shape follows the course of the Tyburn stream that once ran alongside it and pre-dates the grid pattern of the other streets in the area.