Complex sentence: These forms are highly water soluble, show poor lipid solubility, are ineffective at crossing the blood brain barrier, resulting in very little hallucinogenic activity and strong unpleasant effects on the body.
Split into simpler sentences: These forms are highly water soluble and show poor lipid solubility. Such forms are ineffective at crossing the blood brain barrier, resulting in very little hallucinogenic activity and producing strong unpleasant effects on the body.