Complex sentence: APPBP1 is a multi-functional protein with activities in neuronal tissues as well as bonding with UBA3 to form the NEDD8 activating enzyme (NAE).
Split into simpler sentences: APPBP1 is a multi-functional protein with activities in neuronal tissues. APPBP1 also bonds with UBA3 to form the NEDD8 activating enzyme (NAE).