Complex sentence: Zeta-Jones began her acting career at age 12, with the lead role in the stage musical "Annie", and subsequently pursued a career on theatre with appearances in productions, such as West End's "42nd Street".
Split into simpler sentences: Zeta-Jones began her acting career at 12, with the lead role in the stage musical "Annie". She subsequently pursued a career on theatre with appearances in productions, such as West End's "42nd Street".