Complex sentence: The University of Chicago (U of C, Chicago, or UChicago) is a private research university in Chicago, Illinois established in 1890, which holds top-ten positions in numerous national and international rankings.
Split into simpler sentences: The University of Chicago (U of C, Chicago, or UChicago) is a private research university in Chicago, Illinois established in 1890. It holds top-ten positions in numerous national and international rankings.