Complex sentence: When "Homicide" began pre-production, Polito was asked to audition, and was initially reluctant--he didn't want to move to Baltimore for the series, because he had just relocated from New York to Los Angeles.
Split into simpler sentences: When "Homicide" began pre-production, Polito was asked to audition. He was initially reluctant as he didn't want to move to Baltimore for the series, because he had just relocated from New York to Los Angeles.