Complex sentence: The protein needed cannot be synthesised-a completly different protein has been synthesised or a protein similar to the one needed, but not folded correctly; it depends of the site and severness of the frame-shift.
Split into simpler sentences: The protein needed cannot be synthesised-a completly different protein can be synthesised or a protein similar to the one needed, but not folded correctly. Depends of the site and severness of the frame-shift.