Complex sentence: Jesuit missionaries made unsuccessful attempts to establish missions or reductions among the Guaycuruans in the early 1600s, but the first successful mission was established among the Mocobis at San Javier, north of Santa Fe, Argentina in 1743.
Split into simpler sentences: Jesuit missionaries made unsuccessful attempts to establish missions or reductions among the Guaycuruans in the early 1600s. Thee first successful mission was established among the Mocobis at San Javier, north of Santa Fe, Argentina in 1743.