Complex sentence: Charlie and Itchy live in San Francisco as guardian angels, being told of their missions by Anabelle but, this being a family sitcom series, the duo is becoming embroiled in several misadventures in each episode, while trying to do the right thing.
Split into simpler sentences: Charlie and Itchy live in San Francisco as guardian angels, being told of their missions by Anabelle. The series is a family sitcom, with Charlie and Itchy becoming embroiled in several misadventures in each episode, while trying to do the right thing.