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README.md
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---
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task_categories:
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- image-segmentation
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language:
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- en
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tags:
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- medical
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- blood-vessel
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- octa
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pretty_name: (Simulation-Based Segmentation of Blood Vessels in Cerebral 3D OCTA Images
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size_categories:
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- 1K<n<10K
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---
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# syn-cerebral-octa-seg
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<div style="text-align: center;">
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<img src="docs/synthetic3d.jpg" style="width: 70%; height: auto;">
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</div>
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## Introduction
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To accurately segment blood vessels in cerebral 3D Optical Coherence Tomography Angiography (OCTA) images, a vast amount of voxel-level annotations are required. However, the curation of manual annotations is a cumbersome and time-consuming task. To alleviate the need for manual annotation, we provide realistic synthetic data generated via our proposed synthesis pipeline.
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Our proposed synthesis pipeline is described in detail in our manuscript ([Simulation-Based Segmentation of Blood Vessels in Cerebral 3D OCTA Images](https://arxiv.org/abs/2403.07116)). Corresponding code and additional information can be found on [GitHub](https://github.com/bwittmann/syn-cerebral-octa-seg).
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**TL;DR:** *First*, we selectively extract patches from vessel graphs that match the FOV and morphological characteristics of vasculature contained in cerebral OCTA images and transform them into voxelized volumes; *second*, we transform the voxelized volumes into synthetic cerebral 3D OCTA images by simulating the most dominant image acquisition artifacts; and *third*, we use our synthetic cerebral 3D OCTA images paired with their matching ground truth labels to train a blood vessel segmentation network.
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## Dataset Summary
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The voxel size of all provided images is isotropic and corresponds to 2 ΞΌm.
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- [1,137 synthetic cerebral 3D OCTA images with metadata & matching ground truth labels of shape 250 x 250 x 250.](https://huggingface.co/datasets/bwittmann/syn-cerebral-octa-seg/tree/main/synthetic_cerebral_octa)
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```
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synthetic_cerebral_octa/
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βββ axxxx_0/
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βββ sim/
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βββ sim_data_xx.npy # synthetic cerebral 3D OCTA image
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βββ sim_seg_xx.npy # ground truth
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βββ ang.npy # metadata angle
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βββ occ.npy # metadata occupancy below
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βββ rad.npy # metadata radius
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βββ seg.npy # voxelized volume
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βββ axxxx_1/
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...
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```
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- [6 manually annotated OCTA volumes of shape shape 160 x 160 x 160.](https://huggingface.co/datasets/bwittmann/syn-cerebral-octa-seg/tree/main/manual_annotations)
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```
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manual_annotations/
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βββ mx_0.nii # real cerebral 3D OCTA image
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βββ mx_0_label.nii # ground truth (manual annotations)
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...
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```
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## Citation
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If you find our data useful for your research, please consider citing:
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```bibtex
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@misc{wittmann2024simulationbased,
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title={Simulation-Based Segmentation of Blood Vessels in Cerebral 3D OCTA Images},
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author={Bastian Wittmann and Lukas Glandorf and Johannes C. Paetzold and Tamaz Amiranashvili and Thomas WΓ€lchli and Daniel Razansky and Bjoern Menze},
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year={2024},
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eprint={2403.07116},
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archivePrefix={arXiv},
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primaryClass={eess.IV}
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}
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```
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