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Endometrial cancer: Part I. Basic concept. | Authentic |
Innovative Design of a Healthy and Environmentally Friendly Intelligent Cleaning Robot in a Smart City Public Environment. | Counterfeit |
Furthermore, there is a need for more long-term, prospective studies investigating menstrual cycle characteristics as data currently available are primarily retrospective and collected at one time-point only. | Authentic |
However, its potential role remains incompletely understood. | Counterfeit |
The CFB apoptosis was remarkably promoted by miR-33a inhibitor (P < 0.001). | Counterfeit |
Sprague-Dawley (SD) rats were grouped into the sham, I/R, PGRN-high dose, PGRN-low dose, and negative control (NC) groups. | Counterfeit |
PTCH1 expression was significantly decreased in OC tissue compared with normal ovarian tissue and was associated with tumor size, TNM stage, and pathological grade (p < 0.05). | Counterfeit |
microRNA-101 (miR-101) was measured through qRT-PCR. | Counterfeit |
Synergistic enhancement of the antitumor activity of 5-fluorouracil by bornyl acetate in SGC-7901 human gastric cancer cells and the determination of the underlying mechanism of action. | Counterfeit |
Methylation profiling with a panel of cancer related genes: association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer. | Authentic |
The expression levels of miR-203 in BCa tissues, normal adjacent tissues, and BCa cell lines were detected. | Counterfeit |
Periodic acid-Schiff staining of the gastric wall revealed a remarkably intensive uptake of magenta color in the experimental rats pretreated with MHAE compared to the ulcer control group. | Counterfeit |
LINC00607 expression in the TC tissues and cell lines was determined. | Counterfeit |
Our study identifies VGLL4 as an important regulator of PD-L1 expression and highlights a central role of VGLL4 and YAP in the regulation of tumor immunity. | Authentic |
Nevertheless, the therapeutic effect of melatonin in metastatic prostate cancer has largely remained a mystery. | Authentic |
In vitro cell experiments showed that, in comparison to control group, overexpression of microRNA-488-3p significantly weakened the proliferation ability as well as the invasion and migration of NSCLC cells. | Counterfeit |
The antitumor activities of AIL have been reported in several cancers. | Counterfeit |
All were followed up at 6 months after surgery. | Counterfeit |
The microarray analysis revealed a number of hypoxia‑regulated genes that were involved in multiple biological functions. | Authentic |
The biomimetic mBPP NPs could cause drug accumulation at the tumor site, inhibit tumor neovascularization, and improve phototherapy efficiency, providing a novel avenue for cancer treatment. | Counterfeit |
The result obtained in this study indicates that up-regulation of miR-519d inhibits proliferation and promotes apoptosis and autophagy of HCC cells through activation of the AMPK signaling pathway via downregulating Rab10, which provides a potential target for the treatment of HCC. | Counterfeit |
Downregulation of IGF‑1R had tumor suppressive roles similar to that of miR‑379 overexpression on NSCLC cell proliferation, migration and invasion. | Counterfeit |
As for cellular process, miR-21 mimic or siRNA against Sprouty-1 exposure reduced cell viability, which resulted in more cells arrested at the G1 stage, and induced apoptosis. | Counterfeit |
Restoration of miR-302-3p expression caused a significant reduction in cervical cancer cell migration and invasion. | Counterfeit |
Regardless of treatment, men with prostate cancer had a small increase in risk of IHD and stroke and initiation of ET was associated with a further increase in risk of IHD. | Authentic |
Likewise, RCC in the donor organ may not always preclude usage if tumor is small (<2 to 4 cm) and removed with clear margins before transplantation. | Authentic |
We discovered that Bmi1 is important in the cellular response to the transforming growth factor-β/bone morphogenetic protein (TGF-β/BMP) and endoplasmic reticulum (ER) stress pathways, in part converging on the Atf3 transcriptional repressor. | Authentic |
In addition, caerulein was observed to induce injuries in the AR42J cells (depressed cell viability, enhanced cell apoptosis, cytokines production, and levels of amylase). | Counterfeit |
Mesenchymal stem/stromal cell (MSC)-based therapy has become an attractive and advanced scientific research area in the context of cancer therapy. | Counterfeit |
Weight loss, appetite loss and food intake in cancer patients with cancer cachexia: three peas in a pod? - analysis from a multicenter cross sectional study. | Authentic |
A total of 93 cases treated for OTSCC were included in this study. | Authentic |
Abnormal activity of the core cell-cycle machinery is seen in essentially all tumor types and represents a driving force of tumorigenesis. | Authentic |
Conversely, the expression of immune-promoting factors, such as tumor necrosis factor (TNF)-α and IL-6 was significantly downregulated. | Counterfeit |
Phosphorylated protein kinase B (p-AKT), phosphatidylinositol 3-kinase (p-PI3K), and matrix metalloproteinase-2 (MMP2) levels were evaluated by Western blot. | Counterfeit |
Previous studies have indicated a potential association between KIFC1 and cancer progression. | Counterfeit |
Recent researches have proved that long noncoding RNAs (lncRNAs) play an important role in multiple diseases, including malignant tumors. | Counterfeit |
qRT-PCR and Western blot were performed to evaluate the expression of miR-383, PI3K, AKT, mTOR, PARP2, and p70S6K. | Counterfeit |
Cervical cancer (CC) is the 13th most frequent cancer among women in Norway, but the third most common among women aged 25-49 years. | Authentic |
The anti-miR-126 + PIK3R2 siRNA group had significantly decreased PIK3R2, p-PI3K, and p-Akt expressions compared with those of anti-miR-126 alone, as well as significantly decreased proliferation, invasion, and metastasis and increased apoptosis compared with the anti-miR-126 group (all P<0.05). | Counterfeit |
Therefore, these findings suggested that FBXL19-AS1 might serve as an oncogenic lncRNA and promoted BC progression by sponging miR-718, indicating FBXL19-AS1 could serve as a potential therapeutic target for BC treatment. | Counterfeit |
However, all these effects of PCA on cell proliferation, apoptosis, and migration were significantly reversed by PCA + pc-RhoA (p < 0.05 or p < 0.01). | Counterfeit |
In patients with HE4 change >80 and <80 % during NACT, the median OS was 3.38 and 1.60 years (p = 0.01), respectively. | Authentic |
Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining was used to detect the level of apoptosis in lung tissues of rats in each group. | Counterfeit |
However, the genetic events that occur in normal cells prior to tumorigenesis are still unknown. | Authentic |
For subtypes of prostate cancer, the RR was 1.29 (95% CI: 1.08-1.53) for localised, 1.05 (95% CI: 0.87-1.25) for advanced, and 1.14 (95% CI: 0.86-1.51) for fatal cases. | Authentic |
Adhering to the concept of ecological priority, the development of digital technology drove the development of local economy in 2019, accounting for 43% of the national population. | Counterfeit |
The obtained results demonstrated that PCNL is a safer surgical procedure in a high-volume center; however, anemic conditions, infections, and history of open surgery will significantly increase the transfusion rate following PCNL. | Counterfeit |
In the cohort exposed to pioglitazone treatment, 130 bladder cancers occurred over a mean follow-up time of 2.9 years. | Authentic |
A cell counting kit-8 (CCK-8) assay was used to detect and compare the difference among various transfection groups. | Counterfeit |
The clinical applications of glucocorticoids in oncology are mainly dependent on their pro-apoptotic action to treat lymphoproliferative disorders, and also on alleviating side effects induced by chemotherapy or radiotherapy in non-hematologic cancer types. | Authentic |
miR‑489 promotes apoptosis and inhibits invasiveness of glioma cells by targeting PAK5/RAF1 signaling pathways. | Counterfeit |
The present study proposed a promising method combined with scanned laser pico-projection technique and typical texture feature (i.e., contrast, correlation, energy, entropy, and homogeneity) extraction of gray-level co-occurrence matrix (GLCM) image processing model to classify the low- and high-metastatic cancer cells using five common cancer adenocarcinoma cell line pairs (i.e., HeLa/HeLa-S3, CL1-0/CL1-5, OVTW59-P0/OVTW59-P4, and CE81T-FNlow/CE81T-FNhigh cell lines). | Authentic |
88 patients who underwent CRC resection at Colombo South Teaching Hospital, Sri Lanka, from January 2017 to January 2020 were included. | Authentic |
TRIM16 expression has been detected in most tissues. | Counterfeit |
LPS significantly damaged H9c2 cells, as cell viability was reduced, CyclinD1 was down-regulated, apoptosis was induced, the release of interleukin-1β (IL-1β), IL-6, and tumor necrosis factor-alpha were increased, and the phosphorylation of Jnk and c-Jun were promoted. | Counterfeit |
In this study, we aim to investigate the role of tanshinone IIA in myocardial infarction (MI), especially in left ventricular remodelling (VR) and the underlying mechanism involving the TLR4/MyD88/NF-κB signalling pathway. | Counterfeit |
Meanwhile, Gene Ontology (GO) and MetaCore analyses indicated that co-expression of the PTPN1, PTPN5, and PTPN21 genes was significantly enriched in cancer development-related pathways, including GTPase activity, regulation of small GTPase-mediated signal transduction, response to mechanical stimuli, vasculogenesis, organ morphogenesis, regulation of stress fiber assembly, mitogen-activated protein kinase (MAPK) cascade, cell migration, and angiogenesis. | Authentic |
The murine double minute 2 (MDM2) is an oncogene and a negative regulator of the tumor suppressor protein p53. | Authentic |
Long non‑coding RNA (lncRNA) actin filament‑associated protein 1 antisense RNA 1 (AFAP1‑AS1) has been reported to serve important roles in multiple types of cancer. | Counterfeit |
LINC00482 was positively correlated with MMP15. | Counterfeit |
After METTL3 was knocked down in SUNE-1 cells, cell viability and migration abilities were analyzed by cell counting kit-8 (CCK-8) test and wound healing assay, respectively. | Counterfeit |
The relevancy between miR-101 and HULC was investigated by utilizing bioinformatics prediction, luciferase reporter assay, RNA pull-down and immunoprecipitation. | Counterfeit |
Mechanically, miR-101 targeted and negatively regulated BRD4 expression. | Counterfeit |
Here, we describe our genomic analyses of the initial and recurrent tumor specimens from each of 38 GBM patients. | Authentic |
This study was aimed to explore the role of long non-coding RNA ROR in regulations of growth, migration, and angiogenesis of microvascular endothelial cells. | Counterfeit |
Ginsenoside Rg3 inhibits migration and invasion, and promotes apoptosis of Caco-2 cells by suppression expression of LncRNA CCAT1. | Counterfeit |
Dual luciferase reporter gene assay testified miR-10a targeted BDNF. | Counterfeit |
The study aimed to investigate the correlation between the severity of disease and postoperative neurological recovery in patients with cervical spondylotic myelopathy (CSM) combined with developmental spinal stenosis. | Counterfeit |
Stroke is a disease with a high disability rate, having a serious impact on that patient's working and daily survival quality and bringing economic burden to the family and society. | Counterfeit |
Additionally, in MCAO rats, Dex was found to increase the miR-381 expression and reduced IRF4 expression to decrease the IL-9 expression, which suppressed the inflammatory response and cell apoptosis both in vivo and in vitro. | Counterfeit |
The BioGRID database showed that SGSM2 potentially interacts with cytoskeleton remodelling and cell-cell junction proteins. | Authentic |
Reduced tissue and serum resistin expression as a clinical marker for esophageal squamous cell carcinoma. | Authentic |
In univariate analysis, the expression of TATI associated with more favourable cancer-specific survival (p = 0.010). | Authentic |
The expression of miR-34a-5p was downregulated when C2dat1 was overexpressed, whereas it negatively regulated Sirt1 expression. | Counterfeit |
The expression of miR-204, Cotl1, Bax and Bcl-2 was determined. | Counterfeit |
siR-HOTAIR inhibited the proliferation of MG-63 cells due to the induction of G1 phase arrest. | Counterfeit |
Then, wound healing and transwell assays were conducted. | Counterfeit |
Astragaloside IV (AS-IV) has shown anti-tumorigenic properties in certain cancers, but its role in CRC remains unclear. | Counterfeit |
Further investigation showed that overexpression of miR-145 markedly inhibited the protein expression of FSCN1, while knockdown of miR-145 upregulated the protein (but not mRNA) levels of FSCN1 in the NSCLC cell line H129. | Counterfeit |
Endometriosis (EMS) is a gynecologic disorder associated with infertility and characterized by the endometrial-type mucosa outside the uterine cavity. | Counterfeit |
Transwells were used to examine the motility of cancer cells. | Counterfeit |
The expression level of the c-kit was measured by the immunofluorescence assay and the expression levels of CAMKII, FOXO1, and β-catenin were detected by qRT-PCR and western blotting. | Counterfeit |
Overall, we conclude that AIR mediates a transformation on the secretory profile of CAFs that could influence the behavior of other cells in the tumor tissue and hence guide therapeutic outcomes. | Authentic |
Down-regulated H2BK12ac participated in regulating cell proliferation and migration of MG-63 cells, meanwhile, affected the transcription of ERK1/2-downstream genes. | Counterfeit |
Besides, the expression of Bcl-2, Bax, Cleaved-caspase-3, interleukin (IL)-1β, IL-6, IL-8 and cell pathways-related proteins were examined by using Western blot. | Counterfeit |
LEF1-AS1 expression was inhibited by transfecting the LEF1-AS1-specific small interfering RNAs (siRNAs) and stable cell lines established were inhibited by transfecting si-LEF1-AS1 viruses. | Counterfeit |
We demonstrated that COP9 signalosome 5 (CSN5), induced by NF-κB p65, is required for TNF-α-mediated PD-L1 stabilization in cancer cells. | Authentic |
No correlation with survival was found. | Authentic |
By linking to the Swedish Lymphoma Register, subcohort analyses by NHL subtype were performed. | Authentic |
TUNEL stains reflect hippocampal neuron apoptosis. | Counterfeit |
The results demonstrated that BCYRN1 was upregulated in cervical cancer tissues compared with normal tissues. | Counterfeit |
After treatment, miR-655 in serum increased in both the groups and miR-655 in the research group was higher than that in the control group (P < 0.05). | Counterfeit |
The expression of VEGF-C was positively correlated with tumor status and poor clinical prognosis in patient with esophageal cancer. | Authentic |
Both methods, RNA-seq, and microarray showed that Hiltonol and pRNA lead to almost identical changes in the transcriptome of CD141+ mDCs. | Counterfeit |
This study aims to investigate whether microRNA-224 (miR-224) affects the ALEXI mice and the underlying mechanism. | Counterfeit |
Stepwise logistic regression analysis revealed that VEGF-A >16.7 pg/mL 7 days after TACE selected by receiver operating characteristic curve analysis (p < 0.05) was the only independent predictor for rapid growth of HCC (odds ratio 6.33, 95% confidence interval: upper 26, lower 1.54, p < 0.05; sensitivity 76%, specificity 66.7%, accuracy 72.5%, positive predictive level 79.2%, negative predictive level 62.5%, p < 0.01). | Authentic |
USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors. | Authentic |
With the use of this technique, rural public services may efficiently mine user characteristics and offer specific technical support in the modern day. | Counterfeit |
Cardiac troponin T (cTnT), tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) were determined using enzyme-linked immunosorbent assay (ELISA). | Counterfeit |
However, how these mutations collaborate to promote this cancer is unknown. | Authentic |