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Reverse-transcription quantitative polymerase chain reaction analysis indicated that miR-138 was significantly downregulated in LSCC tissues and cell lines.
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Mutant RAS-driven tumorigenesis was thought for decades to arise independently of wild-type RAS isoforms, but recent evidence indicates wild-type isoforms are involved.
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The association between STMN1 expression and EMT-associated markers was investigated in the GC cell lines BGC-803 and SGC-7901.
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Downregulation of miR-122 promoted proliferation and inhibited apoptosis in Hep3B cells.
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we found that treatment with 30 mg/ kg Enbrel® decreased salicylate-induced behavior associated with tinnitus and reduced the mRNA expression levels of TNFR1/R2, NR2B, and DREAM in the cochlea of mice.
Authentic
We show that the m6A demethylase ALKBH5 is highly expressed in glioblastoma stem-like cells (GSCs).
Authentic
In addition, its biological roles in inducing the aggressive phenotype of cervical cancer and its associated mechanisms of action were illustrated.
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Wnt and Hippo signaling pathways play an important regulatory role in HCC development, and their functions are generally considered as positive and negative regulators of cell proliferation, respectively.
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Mechanistically, MACC1-AS1 stabilized MACC1 mRNA and post-transcriptionally augmented MACC1 expression.
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Brain glioma is a malignant tumor with a high incidence rate and poor prognosis that has become a focus of studies of central nervous system diseases.
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Primary rat NSCs were incubated under hypoxia to simulate HIE.
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An miR-216b mimic was introduced into PDAC cells to induce the effects of miR-21b overexpression.
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miR-451's antagomir derepresses YWHAZ expression, thereby enhancing RUNX2 protein stability and promoting osteoblastic differentiation.
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MicroRNA‑152 inhibits cell proliferation, migration and invasion by directly targeting MAFB in nasopharyngeal carcinoma.
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PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing.
Authentic
Lung squamous cell carcinoma (SCC) is a deadly disease for which current treatments are inadequate.
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