bscancar/training_RWD_2 · Datasets at Hugging Face

text stringlengths 1 819	label stringclasses 2 values
Lymph node micrometastases and isolated tumor cells influence survival in stage I and II colon cancer.	Authentic
Mechanistically, PFKFB3 inhibition tightened the vascular barrier by reducing VE-cadherin endocytosis in ECs, and rendering pericytes more quiescent and adhesive (via upregulation of N-cadherin) through glycolysis reduction; it also lowered the expression of cancer cell adhesion molecules in ECs by decreasing NF-κB signaling.	Authentic
However, the underlying molecular mechanisms remain unclear.	Counterfeit
Together, these findings suggest the potential role of PAK3 as a target for pancreatic cancer therapy, which warrants further investigations.	Authentic
Sixty-eight percent (123/181) of the parents who were given medical recommendations reported that their child did not follow the recommendations.	Authentic
Of 48,959 individuals invited to the three first consecutive rounds of screening, 71% participated at least once, and 50% participated in all three rounds.	Authentic
Expression of lncRNA SNHG7 in both RCC cells and 50 pairs of tissue samples was detected by Real-time quantitative polymerase chain reaction (RT-qPCR).	Counterfeit
Reverse transcription-quantitative PCR (RT-qPCR) was used to detect miR-874 expression in CRC cell lines and tissue samples.	Counterfeit
Furthermore, we also demonstrated that HL66, like vinblastine, is a tubulin-destabilizing agent via microtubule disruption in M21 cells.	Authentic
At 3 d and 7d after treatment, the levels of serum EGF, wound blood flow and partial pressure of transcutaneous oxygen in both groups were all increased (P < 0.05), which were higher in the observation group than those in the control group (P < 0.05).	Counterfeit
Our findings provide evidence that the activation of ERS could promote autophagy and apoptosis and reverse chemoresistance of human SCLC cells by inhibiting the PI3K/AKT/mTOR pathway.	Counterfeit
MicroRNA-34a alleviates steroid-induced avascular necrosis of femoral head by targeting Tgif2 through OPG/RANK/RANKL signaling pathway.	Counterfeit
Conclusion: The hsa-circ-0072309 played anti-tumour roles by targeting miR-100 by blocking the PI3K/AKT and mTOR cascades in the CAKI-1 and ACHN cell lines.	Counterfeit
MiiR-16, MEK1, p-ERK1/2, Survivin and Cyclin D1 expression were compared between normal embryonic pituitary cells, HP75 tumor cells.	Counterfeit
Via regulating CX3CL1/CX3CR1 pathway, NP cells can induce the M2 macrophage polarization.	Counterfeit
Esophageal cancer represents the eighth most frequently occurring cancer, as well as the sixth most widespread cause of cancer-related deaths.	Counterfeit
Significant upregulation of phospho-CaMKII levels in acral melanomas was related to increased expression of TRPM1.	Authentic
Accumulating evidence suggests that several immunosuppressive mechanisms may work together in NSCLC.	Authentic
There is limited knowledge of genetic events driving OCCC tumorigenesis beyond ARID1A, which is reportedly mutated in 30-50% of OCCCs.	Authentic
There was no survival difference between patients receiving surgical treatments versus RFA (p = 0.932).	Authentic
Montgomery-Asberg Depression Rating Scale (MADRS) in healthy study subjects, in patients with breast disease and breast cancer: a prospective case-control study.	Authentic
Chronic kidney disease (CKD) is a persistent kidney structural and functional disorder.	Counterfeit
Meanwhile, LY294002 and FVTF synergistically inhibited the characteristics of LCSLCs.	Counterfeit
Among participants, 229 had a plastic stent (PT: n = 138, NAT: n = 91) and 64 had a SEMS (PT: n = 49, NAT: n = 15).	Authentic
Combined impacts of histamine receptor H1 gene polymorphisms and an environmental carcinogen on the susceptibility to and progression of oral squamous cell carcinoma.	Authentic
The bis-benzylidine piperidone RA190 covalently binds to cysteine 88 of ubiquitin receptor RPN13 in the 19S regulatory particle and inhibits proteasome function, triggering rapid accumulation of polyubiquitinated proteins.	Authentic
MALAT1-miR-183-SIRT1 axis and PI3K/AKT/mTOR pathway may be mechanisms to mediate autophagy in GC.	Counterfeit
Compared with the NC group and Mock group, the miR-98 mimics group showed increased miR-98 level while the miR-98 inhibitors group decreased miR-98 level (both P < 0.01).	Counterfeit
The level of hsa_circ_0011946 in HCC tissues and cell lines was monitored by Real Time Quantitative Polymerase Chain Reaction (RT-qPCR).	Counterfeit
Overexpression of SCD1 inhibited Gefitinib-induced apoptosis, decreased cell vitality and impaired ability of migration and invasion, while these effects were counteracted by A939572.	Counterfeit
NORAD expression in clinical PCa tissues and cell lines was detected with the application of qRT-PCR.	Counterfeit
Activation of the p53 pathway has been considered a therapeutic strategy to target cancers.	Authentic
Small interfering RNA silencing was used to knock down target genes.	Authentic
Conclusions: The CCAT2/miR-200b/vascular endothelial growth factor (VEGF) axis plays important regulating effect in OSA through the PI3K/Akt and AMPK pathways.	Counterfeit
Further investigation of the potential molecular mechanism demonstrated that the tumor suppressive functions of miR‑205 in regulating the proliferation, migration and invasion of glioma cells were mediated by a direct target gene, yes associated protein 1 (YAP1).	Counterfeit
MicroRNA-370 functions as a tumor suppressor in hepatocellular carcinoma via inhibition of the MAPK/JNK signaling pathway by targeting BEX2.	Counterfeit
In this review, we summarize the currently available evidence related to the role of Homeobox genes in the development of HCC.	Authentic
Nonetheless, the functions of lncRNA paternally expressed gene 10 (PEG10) in malignant melanoma remain uninvestigated.	Counterfeit
MicroRNAs (miRNAs) are involved in multiple biological activities as well as disease progression including cancer.	Authentic
Our results show the potential impact of incorporating PRS313 directly in the clinical genomic investigation of women with familial BC.	Authentic
Continuous stimulation of the endometrium by estrogen is a risk factor for the tumorigenesis of estrogen receptor (ER) α-positive EEC.	Counterfeit
Comprehensibility and difficulty were assessed by patients for the patient component (PG-SGA Short Form), and by HCPs for the professional component.	Authentic
In addition, silencing of XIST inhibited GC progression in vitro and in vivo.	Counterfeit
The AUC for CRP was 0.77 (95% CI: 0.74-0.80).	Authentic
microRNA-216b enhances cisplatin-induced apoptosis in osteosarcoma MG63 and SaOS-2 cells by binding to JMJD2C and regulating the HIF1α/HES1 signaling axis.	Counterfeit
After exogenous over-expression and knockdown of LINC00858 and the addition of a MAPK pathway inhibitor in GC cells, we explored the effects of LINC00858 and the MAPK signaling pathway on GC cell behavior using various in vitro and in vivo assays.	Counterfeit
The downregulation of MMP-13 and MMP-2 was confirmed at mRNA, protein and tissue levels by qRT-qPCR, Western blot and immunohistochemistry, respectively.	Authentic
In the research group, the monthly family income and the number of family companions and very harmonious families were significantly lower, while the number of divorces or remarriages increased (P < 0.05).	Counterfeit
However, Res was found to suppress this activated Wnt/β-catenin signaling pathway.	Counterfeit
Efficiency of intensified RT (RT with total dose 73.1 Gy or given within 4.5 weeks) was analyzed in relationship to tumor volume.	Authentic
RUVBL1 was consistently overexpressed in all three datasets, although we found inconsistent CNIH expression possibly affected by the diverse major risk factors for ESCC across different areas.	Authentic
Conclusions: PC tissue had higher miR-26a and lower PTEN expressions.	Counterfeit
Moreover, telomere length is not affected and there was no accumulation of oxidative DNA damage compared to wild-type mice.	Authentic
Further studies showed that AuNP-HA/FITC were effectively taken up by A549 cells through CD44-mediated endocytosis.	Authentic
Senescence is increasingly recognized as a critical feature of mammalian cells to suppress tumorigenesis, acting together with cell death programs.	Authentic
In this study, we investigated the role of the lncRNA C2dat1 on the biological functions of osteosarcoma cells.	Counterfeit
Taken together, these results suggest that resistin may have the potential to be developed into a clinical marker for ESCC.	Authentic
The expression levels of matrix metallopeptidase (MMP)-2 and MMP-9 were determined by RT-qPCR and western blot analysis.	Counterfeit
Immune checkpoint blockade plus chemotherapy is emerging as a standard treatment for some patients with triple-negative breast cancer (TNBC).	Authentic
As a collagen organizer and a probable link between contractile fibroblasts and the complex collagen network in tumors, integrin α11β1 could be a potential regulator of tumor PIF.	Authentic
The autophagy rather than apoptosis inducing activity for both H40 and SAHA was observed in prostate cancer PC-3M cells.	Counterfeit
The Sonic hedgehog (Shh) signaling pathway is involved in changes in mammary ducts and malignant transformation.	Counterfeit
HAGLROS level in mantle cell lymphoma cell lines was detected, followed by investigation of the influences of HAGLROS silencing on Mino cell biological performances.	Counterfeit
Cervical cancer is one of the primary causes of cancer-associated mortality worldwide.	Counterfeit
A P-value below 0.05 was considered significant.	Authentic
Diabetes and breast cancer in Taiwanese women: a detection bias?	Authentic
Only pharyngeal (p=0.046) and laryngeal (p=0.047) SCC, but not oral-cavity SCC, had statistically significant associations between heavy smoking and CD44 overexpression when HNSCC was studied in regional groups.	Authentic
Men who underwent all examinations (n = 577) responded that biopsy was more bothersome than PSA test (p < 0.001) and MRI (p < 0.001).	Authentic
DNMT3B may promote the proliferation of NP cells and prevent their ECM degradation through the TRPA1/COX2/YAP axis, thereby alleviating IVDD in rats.	Counterfeit
PD-L1 expression on tumor and immune cells was examined immunohistochemically by using the SP142 antibody and scored by two independent pathologists.	Authentic
miR-376a was found to play tumor suppressive roles in human cancers.	Counterfeit
Findings in the present study may provide miR-122-5p as a novel biomarker for ONFH treatment.	Counterfeit
Herein, we identify a molecular mechanism responsible for reciprocal activation between Aurora B kinase (AURKB) and MYC.	Authentic
The polygenic risk score predicted the risk of PC with an AUC of 0.618 (95% CI 0.60-0.63).	Authentic
Intermittent sun exposure seems to play a major role in SSM, which has an increasing incidence rate during the last decades.	Authentic
The 2,3,5-triphenyltetrazolium chloride (TTC) staining was applied to determine infarct size.	Counterfeit
MicroRNA-148a suppresses epithelial-mesenchymal transition and invasion of pancreatic cancer cells by targeting Wnt10b and inhibiting the Wnt/β-catenin signaling pathway.	Counterfeit
After knockdown of lncRNA ASB16-AS1, the proliferation, cell cycle, and apoptosis of NSCLC cells were detected via cell counting kit-8 (CCK-8) assay, colony formation assay, and flow cytometry, respectively.	Counterfeit
IQGAP1‑siRNA significantly inhibited cell proliferation, and cell adhesion, migration and invasion.	Counterfeit
According to the score of anxiety, the top 27% of the research objects are classified as the high-anxiety group, while the bottom 27% are classified as the low-anxiety group.	Counterfeit
We performed proteomics analyses upon PTK7 knockdown in OC cells and identified novel downstream effectors such as synuclein-γ (SNCG), SALL2, and PP1γ, and these findings were corroborated in ex vivo primary samples using PTK7 monoclonal antibody cofetuzumab.	Authentic
Furthermore, DNP induced LYRIC phosphorylation at serine 568 to facilitate cell motility and invasion, whereas DNP-mediated motility and invasion was decreased when serine 568 in LYRIC was mutated.	Counterfeit
Prospective national population-based cohort study.	Authentic
58.3% patients achieved PASI75 and 43.1% patients achieved PASI90 at M6.	Counterfeit
miR-375-3p targeted BRD4 to activate PI3K/AKT pathway, thereafter to ameliorate myocardial injury in septic rats.	Counterfeit
For every 80-μg/g increase of FIT, there were 1.5-year earlier development of CRC incidence and 1-year earlier development of CRC mortality, respectively.	Authentic
Reversal of promoter DNA hypermethylation and associated gene silencing is an attractive cancer therapy approach.	Authentic
Then, the expression of KRT16, VEGF, and ERK signaling pathway-related genes was detected in psoriatic patients.	Counterfeit
Placental tissues were collected from PE patients and healthy pregnant women, and it was found that let-7d expression was increased, while KDM3A and ENO2 expression was decreased in PE tissues and cells.	Counterfeit
Children and adolescents with JIA are at a slightly increased risk of lymphoproliferative (but not of other) malignancies.	Authentic
Pathogenic germline mutations occurred in eight PCC/PGL susceptibility genes.	Authentic
Overexpression of Bmi‑1 promoted proliferation and angiogenesis, and increased apoptosis resistance induced by cisplatin via the nuclear factor‑κB (NF‑κB) signal pathway.	Counterfeit
The knockdown of SBF2-AS1 or ETS1 or overexpression of miR-338-3p resulted in reduced cell proliferation, migration and invasion but elevated cell apoptosis and autophagy.	Counterfeit
PCAT-1 expression was higher in RAA tissues of AF patients than those of SR patients.	Counterfeit
Increasing evidence has shown that SHC3 is aberrantly expressed in neurons.	Counterfeit
LINC00885 was clearly overexpressed in cervical cancer, which was linked with unfavorable clinical outcomes.	Counterfeit
Overexpression of miR-519d decreased the expression of Rab10, mTOR, and Bcl-2, but increased the expression of Bax, Beclin1, Atg5, and p53.	Counterfeit
H3K27 demethylase KDM6B aggravates ischemic brain injury through demethylation of IRF4 and Notch2-dependent SOX9 activation.	Counterfeit
Cell proliferation, apoptosis, migration, and invasion in vitro, as well as tumor growth in vivo, were determined by CCK-8, flow cytometry, migration and invasion assays, and xenograft models in nude mice, respectively.	Counterfeit
The expression of each gene was determined by RT-qPCR and western blot analysis.	Counterfeit

Lymph node micrometastases and isolated tumor cells influence survival in stage I and II colon cancer.

Authentic

Mechanistically, PFKFB3 inhibition tightened the vascular barrier by reducing VE-cadherin endocytosis in ECs, and rendering pericytes more quiescent and adhesive (via upregulation of N-cadherin) through glycolysis reduction; it also lowered the expression of cancer cell adhesion molecules in ECs by decreasing NF-κB signaling.

Authentic

However, the underlying molecular mechanisms remain unclear.

Counterfeit

Together, these findings suggest the potential role of PAK3 as a target for pancreatic cancer therapy, which warrants further investigations.

Authentic

Sixty-eight percent (123/181) of the parents who were given medical recommendations reported that their child did not follow the recommendations.

Authentic

Of 48,959 individuals invited to the three first consecutive rounds of screening, 71% participated at least once, and 50% participated in all three rounds.

Authentic

Expression of lncRNA SNHG7 in both RCC cells and 50 pairs of tissue samples was detected by Real-time quantitative polymerase chain reaction (RT-qPCR).

Counterfeit

Reverse transcription-quantitative PCR (RT-qPCR) was used to detect miR-874 expression in CRC cell lines and tissue samples.

Counterfeit

Furthermore, we also demonstrated that HL66, like vinblastine, is a tubulin-destabilizing agent via microtubule disruption in M21 cells.

Authentic

At 3 d and 7d after treatment, the levels of serum EGF, wound blood flow and partial pressure of transcutaneous oxygen in both groups were all increased (P < 0.05), which were higher in the observation group than those in the control group (P < 0.05).

Counterfeit

Our findings provide evidence that the activation of ERS could promote autophagy and apoptosis and reverse chemoresistance of human SCLC cells by inhibiting the PI3K/AKT/mTOR pathway.

Counterfeit

MicroRNA-34a alleviates steroid-induced avascular necrosis of femoral head by targeting Tgif2 through OPG/RANK/RANKL signaling pathway.

Counterfeit

Conclusion: The hsa-circ-0072309 played anti-tumour roles by targeting miR-100 by blocking the PI3K/AKT and mTOR cascades in the CAKI-1 and ACHN cell lines.

Counterfeit

MiiR-16, MEK1, p-ERK1/2, Survivin and Cyclin D1 expression were compared between normal embryonic pituitary cells, HP75 tumor cells.

Counterfeit

Via regulating CX3CL1/CX3CR1 pathway, NP cells can induce the M2 macrophage polarization.

Counterfeit

Esophageal cancer represents the eighth most frequently occurring cancer, as well as the sixth most widespread cause of cancer-related deaths.

Counterfeit

Significant upregulation of phospho-CaMKII levels in acral melanomas was related to increased expression of TRPM1.

Authentic

Accumulating evidence suggests that several immunosuppressive mechanisms may work together in NSCLC.

Authentic

There is limited knowledge of genetic events driving OCCC tumorigenesis beyond ARID1A, which is reportedly mutated in 30-50% of OCCCs.

Authentic

There was no survival difference between patients receiving surgical treatments versus RFA (p = 0.932).

Authentic

Montgomery-Asberg Depression Rating Scale (MADRS) in healthy study subjects, in patients with breast disease and breast cancer: a prospective case-control study.

Authentic

Chronic kidney disease (CKD) is a persistent kidney structural and functional disorder.

Counterfeit

Meanwhile, LY294002 and FVTF synergistically inhibited the characteristics of LCSLCs.

Counterfeit

Among participants, 229 had a plastic stent (PT: n = 138, NAT: n = 91) and 64 had a SEMS (PT: n = 49, NAT: n = 15).

Authentic

Combined impacts of histamine receptor H1 gene polymorphisms and an environmental carcinogen on the susceptibility to and progression of oral squamous cell carcinoma.

Authentic

The bis-benzylidine piperidone RA190 covalently binds to cysteine 88 of ubiquitin receptor RPN13 in the 19S regulatory particle and inhibits proteasome function, triggering rapid accumulation of polyubiquitinated proteins.

Authentic

MALAT1-miR-183-SIRT1 axis and PI3K/AKT/mTOR pathway may be mechanisms to mediate autophagy in GC.

Counterfeit

Compared with the NC group and Mock group, the miR-98 mimics group showed increased miR-98 level while the miR-98 inhibitors group decreased miR-98 level (both P < 0.01).

Counterfeit

The level of hsa_circ_0011946 in HCC tissues and cell lines was monitored by Real Time Quantitative Polymerase Chain Reaction (RT-qPCR).

Counterfeit

Overexpression of SCD1 inhibited Gefitinib-induced apoptosis, decreased cell vitality and impaired ability of migration and invasion, while these effects were counteracted by A939572.

Counterfeit

NORAD expression in clinical PCa tissues and cell lines was detected with the application of qRT-PCR.

Counterfeit

Activation of the p53 pathway has been considered a therapeutic strategy to target cancers.

Authentic

Small interfering RNA silencing was used to knock down target genes.

Authentic

Conclusions: The CCAT2/miR-200b/vascular endothelial growth factor (VEGF) axis plays important regulating effect in OSA through the PI3K/Akt and AMPK pathways.

Counterfeit

Further investigation of the potential molecular mechanism demonstrated that the tumor suppressive functions of miR‑205 in regulating the proliferation, migration and invasion of glioma cells were mediated by a direct target gene, yes associated protein 1 (YAP1).

Counterfeit

MicroRNA-370 functions as a tumor suppressor in hepatocellular carcinoma via inhibition of the MAPK/JNK signaling pathway by targeting BEX2.

Counterfeit

In this review, we summarize the currently available evidence related to the role of Homeobox genes in the development of HCC.

Authentic

Nonetheless, the functions of lncRNA paternally expressed gene 10 (PEG10) in malignant melanoma remain uninvestigated.

Counterfeit

MicroRNAs (miRNAs) are involved in multiple biological activities as well as disease progression including cancer.

Authentic

Our results show the potential impact of incorporating PRS313 directly in the clinical genomic investigation of women with familial BC.

Authentic

Continuous stimulation of the endometrium by estrogen is a risk factor for the tumorigenesis of estrogen receptor (ER) α-positive EEC.

Counterfeit

Comprehensibility and difficulty were assessed by patients for the patient component (PG-SGA Short Form), and by HCPs for the professional component.

Authentic

In addition, silencing of XIST inhibited GC progression in vitro and in vivo.

Counterfeit

The AUC for CRP was 0.77 (95% CI: 0.74-0.80).

Authentic

microRNA-216b enhances cisplatin-induced apoptosis in osteosarcoma MG63 and SaOS-2 cells by binding to JMJD2C and regulating the HIF1α/HES1 signaling axis.

Counterfeit

After exogenous over-expression and knockdown of LINC00858 and the addition of a MAPK pathway inhibitor in GC cells, we explored the effects of LINC00858 and the MAPK signaling pathway on GC cell behavior using various in vitro and in vivo assays.

Counterfeit

The downregulation of MMP-13 and MMP-2 was confirmed at mRNA, protein and tissue levels by qRT-qPCR, Western blot and immunohistochemistry, respectively.

Authentic

In the research group, the monthly family income and the number of family companions and very harmonious families were significantly lower, while the number of divorces or remarriages increased (P < 0.05).

Counterfeit

However, Res was found to suppress this activated Wnt/β-catenin signaling pathway.

Counterfeit

Efficiency of intensified RT (RT with total dose 73.1 Gy or given within 4.5 weeks) was analyzed in relationship to tumor volume.

Authentic

RUVBL1 was consistently overexpressed in all three datasets, although we found inconsistent CNIH expression possibly affected by the diverse major risk factors for ESCC across different areas.

Authentic

Conclusions: PC tissue had higher miR-26a and lower PTEN expressions.

Counterfeit

Moreover, telomere length is not affected and there was no accumulation of oxidative DNA damage compared to wild-type mice.

Authentic

Further studies showed that AuNP-HA/FITC were effectively taken up by A549 cells through CD44-mediated endocytosis.

Authentic

Senescence is increasingly recognized as a critical feature of mammalian cells to suppress tumorigenesis, acting together with cell death programs.

Authentic

In this study, we investigated the role of the lncRNA C2dat1 on the biological functions of osteosarcoma cells.

Counterfeit

Taken together, these results suggest that resistin may have the potential to be developed into a clinical marker for ESCC.

Authentic

The expression levels of matrix metallopeptidase (MMP)-2 and MMP-9 were determined by RT-qPCR and western blot analysis.

Counterfeit

Immune checkpoint blockade plus chemotherapy is emerging as a standard treatment for some patients with triple-negative breast cancer (TNBC).

Authentic

As a collagen organizer and a probable link between contractile fibroblasts and the complex collagen network in tumors, integrin α11β1 could be a potential regulator of tumor PIF.

Authentic

The autophagy rather than apoptosis inducing activity for both H40 and SAHA was observed in prostate cancer PC-3M cells.

Counterfeit

The Sonic hedgehog (Shh) signaling pathway is involved in changes in mammary ducts and malignant transformation.

Counterfeit

HAGLROS level in mantle cell lymphoma cell lines was detected, followed by investigation of the influences of HAGLROS silencing on Mino cell biological performances.

Counterfeit

Cervical cancer is one of the primary causes of cancer-associated mortality worldwide.

Counterfeit

A P-value below 0.05 was considered significant.

Authentic

Diabetes and breast cancer in Taiwanese women: a detection bias?

Authentic

Only pharyngeal (p=0.046) and laryngeal (p=0.047) SCC, but not oral-cavity SCC, had statistically significant associations between heavy smoking and CD44 overexpression when HNSCC was studied in regional groups.

Authentic

Men who underwent all examinations (n = 577) responded that biopsy was more bothersome than PSA test (p < 0.001) and MRI (p < 0.001).

Authentic

DNMT3B may promote the proliferation of NP cells and prevent their ECM degradation through the TRPA1/COX2/YAP axis, thereby alleviating IVDD in rats.

Counterfeit

PD-L1 expression on tumor and immune cells was examined immunohistochemically by using the SP142 antibody and scored by two independent pathologists.

Authentic

miR-376a was found to play tumor suppressive roles in human cancers.

Counterfeit

Findings in the present study may provide miR-122-5p as a novel biomarker for ONFH treatment.

Counterfeit

Herein, we identify a molecular mechanism responsible for reciprocal activation between Aurora B kinase (AURKB) and MYC.

Authentic

The polygenic risk score predicted the risk of PC with an AUC of 0.618 (95% CI 0.60-0.63).

Authentic

Intermittent sun exposure seems to play a major role in SSM, which has an increasing incidence rate during the last decades.

Authentic

The 2,3,5-triphenyltetrazolium chloride (TTC) staining was applied to determine infarct size.

Counterfeit

MicroRNA-148a suppresses epithelial-mesenchymal transition and invasion of pancreatic cancer cells by targeting Wnt10b and inhibiting the Wnt/β-catenin signaling pathway.

Counterfeit

After knockdown of lncRNA ASB16-AS1, the proliferation, cell cycle, and apoptosis of NSCLC cells were detected via cell counting kit-8 (CCK-8) assay, colony formation assay, and flow cytometry, respectively.

Counterfeit

IQGAP1‑siRNA significantly inhibited cell proliferation, and cell adhesion, migration and invasion.

Counterfeit

According to the score of anxiety, the top 27% of the research objects are classified as the high-anxiety group, while the bottom 27% are classified as the low-anxiety group.

Counterfeit

We performed proteomics analyses upon PTK7 knockdown in OC cells and identified novel downstream effectors such as synuclein-γ (SNCG), SALL2, and PP1γ, and these findings were corroborated in ex vivo primary samples using PTK7 monoclonal antibody cofetuzumab.

Authentic

Furthermore, DNP induced LYRIC phosphorylation at serine 568 to facilitate cell motility and invasion, whereas DNP-mediated motility and invasion was decreased when serine 568 in LYRIC was mutated.

Counterfeit

Prospective national population-based cohort study.

Authentic

58.3% patients achieved PASI75 and 43.1% patients achieved PASI90 at M6.

Counterfeit

miR-375-3p targeted BRD4 to activate PI3K/AKT pathway, thereafter to ameliorate myocardial injury in septic rats.

Counterfeit

For every 80-μg/g increase of FIT, there were 1.5-year earlier development of CRC incidence and 1-year earlier development of CRC mortality, respectively.

Authentic

Reversal of promoter DNA hypermethylation and associated gene silencing is an attractive cancer therapy approach.

Authentic

Then, the expression of KRT16, VEGF, and ERK signaling pathway-related genes was detected in psoriatic patients.

Counterfeit

Placental tissues were collected from PE patients and healthy pregnant women, and it was found that let-7d expression was increased, while KDM3A and ENO2 expression was decreased in PE tissues and cells.

Counterfeit

Children and adolescents with JIA are at a slightly increased risk of lymphoproliferative (but not of other) malignancies.

Authentic

Pathogenic germline mutations occurred in eight PCC/PGL susceptibility genes.

Authentic

Overexpression of Bmi‑1 promoted proliferation and angiogenesis, and increased apoptosis resistance induced by cisplatin via the nuclear factor‑κB (NF‑κB) signal pathway.

Counterfeit

The knockdown of SBF2-AS1 or ETS1 or overexpression of miR-338-3p resulted in reduced cell proliferation, migration and invasion but elevated cell apoptosis and autophagy.

Counterfeit

PCAT-1 expression was higher in RAA tissues of AF patients than those of SR patients.

Counterfeit

Increasing evidence has shown that SHC3 is aberrantly expressed in neurons.

Counterfeit

LINC00885 was clearly overexpressed in cervical cancer, which was linked with unfavorable clinical outcomes.

Counterfeit

Overexpression of miR-519d decreased the expression of Rab10, mTOR, and Bcl-2, but increased the expression of Bax, Beclin1, Atg5, and p53.

Counterfeit

H3K27 demethylase KDM6B aggravates ischemic brain injury through demethylation of IRF4 and Notch2-dependent SOX9 activation.

Counterfeit

Cell proliferation, apoptosis, migration, and invasion in vitro, as well as tumor growth in vivo, were determined by CCK-8, flow cytometry, migration and invasion assays, and xenograft models in nude mice, respectively.

Counterfeit

The expression of each gene was determined by RT-qPCR and western blot analysis.

Counterfeit