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In the present study, we stained sections of frontal lobe autopsy tissue from cancer patients treated with chemotherapy (n = 15), cancer patients not treated with chemotherapy (n = 10), and patients without history of cancer (n = 10) for markers of oxidative stress (nitrotyrosine, 4-hydroxynonenal) and DNA damage (pH2AX, pATM).
not china
This analysis provides a new framework that connects alternative metrics of response to overall survival.
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For SLNRT, dose regimens were normo- or slightly hypo-fractionated with a simultaneous boost to the PET-positive recurrences.
not china
We recorded information on patient demographics, HIV status, primary care providers, and cervical screening, including date, results, and type of health care provider ordering the screening.RESULTS Fifty-eight percent (126 of 218) of the women had at least 1 cervical screening test during the 3-year period.
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We compared local CTC features between the groups of complete (n = 74) and incomplete colonoscopy (n = 34).
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We have identified six mutations in CCK2R among a panel of 140 colorectal cancers and 44 gastric cancers.
not china
MI192 therefore shows the potential as a new drug candidate for CCA therapy.
china
Using NTx-PD-1(-/-) mice, we found that in AIG lesions, interferon-γ, and tumor necrosis factor (TNF)-α together with interleukin-21 (IL-21) were highly expressed in the inflamed gastric mucosa.
not china
Incidence and mortality of intrahepatic cholangiocarcinoma (ICC) have been increasing over the past few decades, and Ki67 is an adverse prognostic predictor and an attractive therapeutic target for ICC patients.
china
The median follow-up was 4.5y.
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Development of models was constructed in a primary cohort based on preoperative ultrasound features and clinicodemographic data from August 2020 to December 2021.
china
A prospective pilot study addressed the question if addition of FRWBH to re-irradiation is feasible in recurrent head and neck squamous cell carcinomas (HNSCC) with unfavorable prognostic features.
not china
These HPV-positive cells, compared to HPV-negative, showed different gene expressions related to the extracellular matrix, cell adhesion, proliferation, and apoptosis.
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LncRNA profiling shows distinct differentially expressed lncRNAs in parathyroid neoplasm.
china
The complex interplay between macrophages and tumor cells through several soluble factors and signaling is an important factor in breast cancer progression.
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Here, we report that H-DNA-forming sequences are enriched at translocation breakpoints in human cancer genomes, further implicating them in cancer etiology.
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The induction of HIF-1α response element activity and cell retention of HIF-1α were not increased by Y208C overexpression.
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Cell migration, invasion and proliferation were detected by transwell assays and Cell Counting Kit-8 (CCK-8) assays.
china
The molecular subtype was identified according to 2013 St Gallen consensus, and HER2 status was also re-determined following 2018 ASCO/CAP guideline.
china
The IHC score demonstrated that the CRIP1 protein was expressed at a higher level in tumours than in tumour-adjacent tissues and was associated with a higher pathological stage, grade, and positive lymphatic metastasis.
china
Pancreatic duct adenocarcinoma (PDAC) is an aggressive and lethal malignancy.
not china
This study employed a relatively non-invasive approach to establish an orthotopic hepatocellular carcinoma model in immune-competent rats.
not china
However, the late complication of intestinal obstruction occurred only in the JI group.
not china