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Moreover, colon mucosa was examined from 30 cases with no evidence of cancer as a control. | not china |
A NSCLC-identification algorithm based on free-text keywords and SNOMED morphology and topography codes was designed and tested on data from Siena: indication for drug use (i.e. | not china |
The four MLL-related acute leukemia models showed a different course of infant and adult MLL-AF9 acute myeloid leukemia, and a rapid aggressiveness of MLL-ENL acute lymphoblastic leukemia and MLL-AF4 acute biphenotypic leukemia. | not china |
There are remarkable differences between pulmonary lobectomy and partial pulmonary lobectomy. | china |
We aimed to investigate predictive factors of occult lymph node metastasis and to explore the diagnostic value of various standardized uptake value (SUV) parameters using fluorine-18 fluorodeoxyglucose (F-FDG) positron emission tomography computed tomography (PET/CT) in predicting occult lymph node metastasis of clinical N0 non-small cell lung cancer patients. | china |
Primary carcinoma of cystic duct is a rare condition comprising a fraction of all extrahepatic bile duct malignancies with less than 70 cases reported worldwide. | not china |
Myelopoiesis is under the control of a complex network containing various regulation factors. | china |
It has been suggested that the use of papaverine prior to the infusion of melphalan might increase its efficacy, but it may also increase toxicity. | not china |
Electronic literature databases and reference lists of relevant articles revealed a total of 10, 6 and 6 published studies for the Arg399Gln, Arg194Trp and Arg280His polymorphisms, respectively. | china |
The optimal cutoff value of NMPR concerning overall survival (OS) in the training cohort was determined by X-tile software. | china |
Median follow up was 5.0 years (range 0.1-16.7 years). | not china |
Both MB + Tc99m and MB + ICG can be used as effective mapping methods in SLNB of early-stage breast cancer to improve the detection rate. | china |
Antisense lncRNAs are poorly quantified by alignment-based gene quantification methods, which can be improved using stranded protocols and pseudoalignment methods. | not china |
Analysis of breast cancer prognostic and predictive factors revealed that the -1082AA genotype was associated with a significantly increased risk of lymph node (LN) involvement (P = 0.041) and larger tumor size (P = 0.039) at the time of diagnosis. | china |
An elevated preoperative dNLR may be an independent prognostic biomarker for RFS in patients undergoing total laryngectomy with LSCC. | china |
Elevated platelet volume is the risk factor for the development and poor overall survival of colorectal cancer (CRC) patients. | china |
Prognosis of lymphoma associated HLH is very poor, especially in T cell lymphomas; and, therefore, early diagnosis might alter the outcome. | not china |
The present study showed no significant associations between individual nutrient intake and BC risk. | not china |
SNB should be considered in cases where tumour thickness is ≥2 mm and actively performed in cases ≥5 mm. | not china |
It results from an inappropriate parathyroid hormone (PTH) secretion relative to serum ionized calcium level. | not china |
On univariate analysis, carcinoembryonic antigen, cytokeratin 19 fragment, lobulation, and all PET parameters were associated with occult lymph node metastasis. | china |
The relationship between salivary gland tumors and immune system has not been well inspected. | not china |
The RNA-seq expression data, single nucleotide variants (SNV), short insertions and deletions (InDel) mutation data, copy number variation (CNV) data and clinical follow-up information data of gastric cancer tissues were downloaded from The Cancer Genome Atlas (TCGA) database. | china |
Clinically significant PCa (csPCa), defined as Gleason-based Grade Group 2 or higher, was detected in 934 men (38.4%). | not china |
We hypothesized ICH ligands CXCL9-11 and CCL2-5 would be associated with intratumoral T-cells, while CXCL13 would be more associated with B-cell infiltrates. | not china |
The aim of this study was to assess morbidity and associated factors in patients with lung cancer (LC). | not china |
The strategies to increase miR-34a level might be a critical targeted therapy for HCC in future. | china |
Baohuoside-1 significantly inhibited the proliferation, invasion and migration of two liver cancer cell lines. | china |
Clarity in the measurement of timeliness provides a standardized language for monitoring and outcome research. | not china |
Patients with cervical cancer metastasized to DLN have favorable survival compared to those with pelvic organ invasion or with distant organ(s) metastasis. | china |
Our results meet the pre-specified primary endpoint. | china |
In the Cox regression test, constitutive photomorphogenesis 9 subunit 6 protein was not shown to be an independent prognostic factor for breast cancer. | china |
In an era of increasing support for adjuvant treatment modalities in the management of meningiomas, our data support maximal safe resection as the primary goal in treatment of these patients. | not china |
In this study, we investigated genetic variants from seven OSCC risk loci identified in non-African populations for association with OSCC in the South African Black population. | not china |
E-cadherin expression may be involved in gastric cardia carcinogenesis and low expression of E-cadherin may be a promising early biomarker and overall survival predictor for GCA. | china |
Parotid FNAC indicated a squamous cell carcinoma. | not china |
Researchers have used high-throughput sequencing technology to identify many noncoding transcripts related to the development of HCC and have studied the interaction between these transcripts and DNA, RNA, or protein to determine the relevant mechanism in the development of HCC. | china |
The GST gene polymorphisms were evaluated in 197 cases and 514 controls by PCR-RFLP-Polymerase Chain Reaction Restriction Fragment Length Polymorphism. | not china |
The anticarcinogenicity effects corroborated the observed reduction in levels of pituitary prolactin. | not china |
False negative results may be get because of limited biopsy material. | china |
In the context that enoxacin is an FDA-approved antibiotic, and that entinostat is an investigational agent not yet FDA-approved, we propose enoxacin as an adjuvant drug for further preclinical and clinical investigation in EWS patients. | not china |
HBV (p = 0.022), arterial rim enhancement (p = 0.006) and enhancement pattern (p = 0.012) are independent clinicoradiological features. | china |
The preoperative enhanced CT images were retrospectively analyzed for ascites, hepatic scalloping, omental and peritoneal lesion appearance, intralesional calcification and septa, and peripheral organ involvement. | china |
Accurate risk prediction models using routinely measured biomarkers-eg, carbohydrate antigen 19-9 (CA19-9) and bilirubin serum levels-for pancreatic cancer could facilitate early detection of pancreatic cancer and prevent potentially unnecessary diagnostic tests for patients at low risk. | not china |
The radiomics model reached an AUC (95% confidence interval [CI]) of 0.979 (0.935-0.996) and 0.894 (0.796-0.956) in the training and test dataset, respectively. | china |
All the detected HBV patients belonged to HBV genotype D, and mutations were found in the surface genome of HBV leading to occult HBV. | not china |
Also, the frequency of LF differed significantly between the two risk groups (63% vs. 20% at 24 months, p < 0.001, HR 0.158, 95%CI 0.054-0.458). | not china |
Hep1-6 and HepG2 cells were treated by Rg3 in different concentrations (0, 50, 100 and 200 μg/mL) in vitro. | china |
Pm-Pac plus cisplatin yielded superior ORR and PFS along with a favorable safety profile and should become an option for patients with advanced NSCLC. | china |
We analyzed data from the database of Gene Expression Omnibus (accession number: GSE11877) using bioinformatical and statistical methods. | china |
Furthermore, ABI2 knockdown inhibited HCC sphere formation and decreased the CD24+ , CD133+ and CD326+ CSCs populations, suggesting the suppression of HCC stemness characteristics. | china |
Results from this meta-analysis suggested that dietary total fat and fatty acids might be not associated with risk of breast cancer. | china |
The meta-analysis showed that use of an MS was associated with lower rates of reintervention (p < 0.00001), delay of NAT (p = 0.007), recurrent biliary obstruction (RBO) (p = 0.003), and cholangitis (p = 0.03). | china |
These results were obtained after adjustments by the variables age and presence of chronic diseases. | not china |
This study investigated the anti-proliferative effect of Licarin A (LCA) from Myristica fragrans in non-small cell lung cancer cell lines-A549, NCI-H23, NCI-H520 and NCI-H460. | not china |
([7]) Importantly most of the innovations in cell based therapies in the world have been made in Japan because immunotherapy is a part of the Japanese Health care system and routine therapies for cancer in Japan. | not china |
Reduction of eEF1A2 expression in DU-145 and PC-3 cells led to a dramatic inhibition of proliferation accompanied with enhanced apoptosis rate. | china |
Inhibition of DNA methylation enabled sustained IL-15Rα expression induced by activation. | not china |
In contrast, there was no difference in the expression levels of the NUP98-NSD1 fusion or its proposed targets HoxA5, HoxA7, HoxA9 or HoxA10 between animals with different latencies to develop disease. | not china |
However, the potential analgesic actions of SPMs in chemotherapy-induced peripheral neuropathy (CIPN) are not known. | not china |
Validation of the models was then performed on an independent cohort between January and March of 2022. | china |
Patients with a low m6Ascore displayed a low abundance of PD-1, CTLA-4 and TIGIT, however, the IPS showed no difference between the two groups. | china |
In conclusion, we demonstrated that both TMEFF2 and SMOC-2 were highly expressed in EC and were associated with a shortened survival rate, dismal outcome, and poor prognosis in EC patients. | not china |
Despite this, several of these species are yet to be tested for anticancer activity. | not china |
Multivariate analysis shows that Carcinoembryonic antigen (CEA), Carbohydrate antigen19-9 (CA19-9), and lymphadenopathy on imaging are independent risk factors for lymph node metastasis. | china |
Bilateral PTC was found in 72.8% of the patients with BRAF V600E mutation, and in 42.0% of the patients without the mutation. | china |
Death was confirmed by query of the Social Security Death Index. | not china |
However, OW status raises endometrial cancer risk even among women with lower insulin levels, suggesting that obesity-related pathways are relevant for the development of this cancer beyond insulin. | not china |
Matrigel assays revealed that propranolol displays potent anti-angiogenic properties at non-toxic concentrations (less than 50 μM) but exert no vascular-disrupting activity. | not china |
Our results showed an increase in demand for health services from 2 months before diagnosis of cancer. | not china |
We also compared the effect of IGF1R up-regulation and IGF1R inhibition on viability and apoptosis of NCI-H446 cells. | china |
Copper is one of the most used therapeutic metallic elements in biomedicine, ranging from antibacterial approaches to developing new complexes in cancer therapy. | not china |
STRING was used to evaluate interactions between the target genes, and the relationship between ALKBH5 target gene expression and LUAD patient prognosis was analyzed using the R package Survminer. | china |
CCBE1 is expressed in various tumors and its expression correlates with lymphangiogenesis and angiogenesis. | china |
The pre-treatment apparent diffusion coefficient (ADC) maps derived from DW-MRI of ten GBM patients treated with radical chemoradiotherapy were used to calculate the local cellular density based on published data. | not china |
TTTY14 knockdown significantly inhibited the proliferation of TGCT in vitro. | china |
Combined treatment with RC-3940-II and chemotherapeutic agents 5-FU and irinotecan resulted in a synergistic tumor growth suppression of HT-29, HCT-116 and HCT-15 xenografts by 43% to 78%. | not china |
Of the 26 patients, recurrence or metastasis was observed in 5 cases (19.2%). | not china |
The aim of the present study was to investigate the relation between vitamin D intake and BC risk. | not china |
Monomethyl auristatin E (MMAE) is the most popular and widely used cytotoxin in the development of antibody-drug conjugates (ADCs). | china |
After the additional evaluation of PET/CT, 18.5% (10/54) turned from nerve-sparing surgery to non-nerve sparing surgery. | china |
Quantitative CEUS analysis can reveal changes in tumor perfusion following NACT. | china |
Logistic regression analysis was used to evaluate independent predictors. | china |
In vitro RNA-RNA interaction and messenger RNA (mRNA) stability assays were performed to explore the mechanisms. | china |
Research over the last decade has made great strides in our understanding of lncRNAs, especially in the biology of their role in cancer. | not china |
Accuracy in metastatic hepatic lesions HD, presacral soft tissue, lung nodules, H, and N cancer, breast cancer, NHL and mediastinal LN was100%, 88.8%, 80%, 78%, 75%, 75%, 71%, and 33.3%, respectively. | not china |
The two parameters of RV ejection fraction and RV fractional area change in the carvedilol group with a mean of 66.41% ± 8.10% and 51.85% ± 6.89% were slightly higher than the control group with a mean of 64.58% ± 6.83% and 50.48 ± 5.79%, respectively, which was not statistically significant (P > 0.05). | not china |
The lesion location and degree of differentiation were the independent influencing factors for thoracic LRR and distant metastasis, respectively. | china |
Here, we employed an integrated transcriptomic and quantitative proteomic analysis to systematically explore the regulatory role of HOTAIR in HCC. | china |
Median OS was not significantly different between the two groups. | china |
Effective biochemical and clinical control rates may be safely achieved administering SRT with high doses (≥72 Gy) and using conformal techniques, especially in older patients presenting with lower pre-SRT PSA values. | not china |
Conclusion: The patients who received consolidation chemotherapy showed significantly better DFS. | china |
The patient was insensitive to ATRA and ATO but responded well to homoharringtonine and cytarabine. | china |
SIGNIFICANCE OF THE STUDY: Eupatilin inhibited proliferation via promoting apoptosis and cell cycle arrest in HeLa and Caski cervical cancer cell lines. | china |
For MMP3 (-1171) 5A/6A, the polymorphism decreased the overall risk of metastasis under two genetic models (recessive: OR = 0.80, 95%CI = 0.64-0.99, dominant: OR = 0.72, 95%CI = 0.56-0.93). | china |
Late rectal bleeding (>grade 2) was observed in 12/159 patients (7.5%). | not china |
Survivin is a tumor-associated antigen with significant potential as a cancer vaccine target. | not china |
In conclusion, SWI/SNF complexes are recurrently altered in hematological malignancies and some SWI/SNF subunits may be essential for tumor maintenance. | not china |
Interaction of epithelial cells with basement membrane (BM) is mediated by cell-adhesion molecules, which regulate cell proliferation, motility, and differentiation by integrating signals from extracellular matrix and soluble factors. | not china |
A total of 2120 patients with RCC from Fudan University Shanghai Cancer Center (FUSCC) database and 74 506 counterparts from SEER database were included. | china |