bscancar/elite_set_balanced · Datasets at Hugging Face

text stringlengths 1 858	label stringclasses 2 values
The fourth factor is that cancer cells may be deficient in chromosome healing, the de novo addition of telomeres to the sites of DSBs, a mechanism that prevents chromosome instability resulting from DSBs near telomeres.	Authentic
MiR-182 functions as an anti-oncogene in ccRCC, and miR-182-mediated inhibition of cell migration and invasion might be through directly targeting IGF1R.	Counterfeit
In addition, circ_0061140 may enhance the proliferation rate and invasion ability of BCa cells through the modulation of microRNA-1236.	Counterfeit
The SCD1 mRNA level was detected by qPCR.	Counterfeit
Seven miRNAs, miR-21, miR-32, miR-99a, miR-99b, miR-148a, miR-221 and miR-590-5p, were found to be differentially expressed in CRPC compared with benign prostate hyperplasia (BPH) according to microarray analyses.	Authentic
Notably, rheumatic adverse events occurred at a higher rate (15.5%) than previously reported.	Authentic
Upregulated miR-132 or silenced PTEN activated the PI3K/Akt pathway, thus facilitating cardiocyte proliferation and repressing cardiocyte apoptosis and cardiac fibrosis, as well as inflammatory responses.	Counterfeit
Because mutations in these genes can compromise the efficacy of epidermal growth factor receptor blockade in CRC patients, identifying mutations that confer resistance to some targeted treatments may be useful to guide therapeutic decisions.	Authentic
Cancer Res; 76(8); 2288-300.	Authentic
Whole-brain radiation therapy, large tumors, young age at diagnosis, and male gender are risk factors for late cognitive sequelae after pediatric brain tumors.	Authentic
In the follow-up total cancer recurrence did not differ (P=0.187).	Authentic
EZH2 methylated STAT3 and enhanced STAT3 activity by increased tyrosine phosphorylation of STAT3, thereby increasing apoptosis and release of pro-inflammatory cytokines in ox-LDL-treated HUVECs.	Counterfeit
The regulatory effects of circ_0075825 and miR-432-5p on SOX9 protein expression were probed by western blot.	Counterfeit
In this study, 21 cases of large arterial blood vessel IS were analyzed by immunohistochemistry and fluorescence in situ hybridization and selectively by karyotyping, array comparative genomic hybridization, sequencing, phospho-kinase antibody arrays, and Western immunoblotting in search for novel diagnostic markers and potential molecular therapeutic targets.	Authentic
Although >85% of GIST patients treated with the small-molecule inhibitor imatinib mesylate (Gleevec) achieve disease stabilization, complete remissions are rare and a substantial proportion of patients develop resistance to imatinib over time.	Authentic
The current study provides evidence that LINC00922 acts as a tumor promoter by promoting NKD2 methylation.	Counterfeit
According to the COX regression analysis, MALAT1 expression, tumor size, and TNM stage were independent influencing factors of GBC patients' survival condition.	Counterfeit
The incidence of postoperative pain and discomfort in group B was lower than that in group A, and the difference between the two groups was statistically significant (P < 0.05); the incidence of postoperative chest pain, bleeding, pneumothorax, pulmonary infection, and atelectasis in group B was lower than that in group A, and the difference between the two groups was statistically significant (P < 0.05).	Counterfeit
Healthcare professionals need sufficient courage and willingness to share their patients' thoughts, beliefs, and grief to be able to guide patients toward improving their SWB.	Authentic
Five patients received computer-assisted dose-planned radiotherapy with curative intent (total dose 60-70.5 Gray), and two patients received radiotherapy as palliation.	Authentic
Plasma glucose, insulin, fructosamine, protein glycation, and blood glycated hemoglobin (HbA1C) were measured.	Counterfeit
Collectively, NAC could ameliorate COPD-induced pulmonary fibrosis by promoting immune response and inhibiting EMT process via the VWF/p38 MAPK axis, therefore providing us with a potential therapeutic target for treating COPD.	Counterfeit
We confirmed that miR-96-5p could directly target FOXF2 by luciferase reporter assay.	Counterfeit
In contrast, proliferating GNPs as well as MB and GBM express low or no ZNF238.	Authentic
The effects EBF1 gene and MAPK axis had on cell proliferation, apoptosis, and migration were determined by in vitro cell culturing.	Counterfeit
At visual evaluation, 13 of the HCC's were positive at PET-examination using FDG and 34 were positive using (11)C-acetate (p<0.001).	Authentic
Microarray-based gene expression profiling of AMI was conducted in order to identify differentially expressed genes (DEGs) and the corresponding miRs regulating these genes.	Counterfeit
miR-199a abrogated the protective effects of quercetin against hypoxia-elicited damages.	Counterfeit
Absent androgen receptor expression was associated with strong expression of chromogranin A (p = .02) and neuron specific enolase (p = .02), but not with focal expression of any marker.	Authentic
Gastric cancer tissues and corresponding adjacent normal tissues were extracted from patients.	Counterfeit
HF rats presented with downregulated expressions of Sirt1, brain-derived neurotrophic factor (BDNF) and exhibited upregulated expressions of NF-κB p65 and miR-155.	Counterfeit
The aim of the present study was to identify genes involved in hypoxia‑mediated responses to radiotherapy in HNSCC.	Authentic
The survey study, in turn, was based on earlier findings from a qualitative study of cancer patients in Sweden.	Authentic
Mean follow-up after VT was 95.0 months (range 26.5-182.4).	Authentic
Overexpression of miR-126 inhibited LP6 expression on mRNA and protein levels, and deactivate Wnt/β-catenin signaling pathway.	Counterfeit
ciRS-7 exerted influence on apoptosis, viability, migration, and tube formation through mediating PI3K/AKT and JNK/p38 pathways by miR-26a-5p downregulation in HMEC-1 cells.	Counterfeit
Icariin (ICA) is obtained from Epimedium brevicornu maxim and exploited to remedy miscellaneous cancers.	Counterfeit
Functional assays were utilized to test the inflammatory responses, oxidative stress, and pyroptosis using reverse transcription quantitative polymerase chain reaction, Western blotting, immunohistochemistry, immunofluorescence, and ELISA.	Counterfeit
MMP-13 and Col II expression in cartilage tissues was assessed; expression of β-catenin and Col2A1 in cartilage tissues was assessed.	Counterfeit
Entire 1992-1995 male (40,852) and female (39,420) birth cohorts were invited, and 11,662 males and 20,513 females vaccinated with 20-30% and 45% coverage in 2007-2010.	Authentic
Recent advances in the molecular characterization of bladder cancer have shown the potential role for DNA damage repair (DDR) gene alterations and molecular subtypes to guide therapy, but these need validation from prospective clinical trials.	Authentic
Bladder cancer (BCa) is a heterogeneous disease that poses great threats on public health.	Counterfeit
MicroRNAs (miRNAs) as central regulators have been discovered in colon cancer.	Counterfeit
Expression of IL-1β, miR-9-5p, TPX2, amyloid-β (Aβ) and p-tau in mouse hippocampal tissues was determined.	Counterfeit
The automated Ki-67 assessment method appears to be comparable to the visual method in synovial sarcoma and had a significant association to overall survival.	Authentic
ARF inhibits nucleolar import of TTF-I by binding to this nucleolar localization sequence, causing the accumulation of TTF-I in the nucleoplasm.	Authentic
In vitro results were reproduced in in vivo experiments.	Counterfeit
Hence, this study investigated the role of HNF1A-AS1 in angiogenesis of colon cancer.	Counterfeit
Our study reveals a new molecular mechanism of Coronin 3 in promoting glioma growth and development through regulating the Wnt/β-catenin signaling pathway.	Counterfeit
Additionally, the aim was to compare SF SP and PGE2 between osteoarthritic and non-osteoarthritic joints, and investigate associations between SP, PGE2, osteoarthritic pain, and the signalment of dogs.	Authentic
Cancer and non-tumoral tissues were collected, in which HEIH, miR-185 and KLK5 expression were detected, as well as their correlations.	Counterfeit
Gross total resection (GTR) was achieved in 118 patients and 5-year overall survival for patients with GTR versus those with non-GTR differed significantly with 64% versus 22%.	Authentic
Our results revealed that mice with I/R-induced hepatic injury showed higher serum levels of blood glucose, lipids, ALT and AST and leukaemia inhibitory factor (LIF) expression, and lower HIF1α and ZEB1 expression (P < .05), which were reversed after remifentanil treatment (P < .05).	Counterfeit
Compared with the control group, protein expressions of VEGF, NF-κB, p-IκB/IκB, expression of ANRIL, and mRNA expressions of VEGF, FLT-1 and NF-κB were increased in the DM + CI group.	Counterfeit
Regarding the mechanism, PTPRG-AS1 could serve as a competing endogenous RNA in EOC cells by decoying microRNA-545-3p (miR-545-3p), thereby elevating histone deacetylase 4 (HDAC4) expression.	Counterfeit
Recently, the long noncoding RNAs (lncRNAs) have been demonstrated to be involved in the development of various renal diseases.	Counterfeit
To achieve the measured variability, one is necessarily led to assume a wide variation from patient to patient of the sensitive cells' response to the therapy.	Authentic
Together, these findings establish that Gd-DTPA-based DCE-MRI can noninvasively visualize tumor IFP, and they reveal the potential for v(0) determined by this method to serve as a novel general biomarker of tumor aggressiveness.	Authentic
These data provided strong evidence that miR-130a may be involved in the progression of OSAHS-associated PHT by down-regulating GAX gene.	Counterfeit
We found that IL-1β induced a significantly inflammatory injury in CHON-001 cells.	Counterfeit
Transient activation of ER stress with carbon monoxide drives mitochondrial biogenesis and protective autophagy that elicits superior antitumor T-cell function, revealing an approach to improving adoptive cell efficacy therapy.	Authentic
Thus, experiments were designed to test the hypothesis that HBx triggers malignant transformation by promoting properties that are characteristic of cancer stem cells (CSC).	Authentic
Overexpression of LINC00261 inhibited prostate cancer cells proliferation, migration, and invasion as well as angiogenesis, which could be reversed by silencing DKK3.	Counterfeit
MTDH overexpression in MKN45 cells increased the levels of P-glycoprotein (P-gp) and promoted 5-FU resistance, while inhibition of MTDH showed the opposite result.	Counterfeit
Compared to controls, the tumor area in zebrafish treated with bilberry powder (10 and 25 µg/mL) was reduced significantly (p = 0.038 and p = 0.021, respectively), but the number of fish with metastases did not differ between groups.	Authentic
Hdac3 augmented the recruitment of p65 in the Pgf promoter region through the miR-17/EZH1 axis, thus enhancing the transcription and expression of Pgf, which elicited abnormal angiogenesis and alveolarization of BPD mice.	Counterfeit
Background: Histone H1.5 has been considered as a novel cancer marker as its expression is associated with various human cancers.	Counterfeit
This modernization brings about other forms of physical education, being student centered and more interactive.	Counterfeit
However, the receptor-signal transduction was silenced, revealing no Ca(2+) mobilization or cell-cycle entry, while phosphorylated extracellular-regulated kinase 1/2 basal levels were high and could not be elevated further by oxidized low-density lipoprotein.	Authentic
Bioinformatics analysis showed a targeting relationship between miR-205 and the 3'-UTR of YAP1.	Counterfeit
The aim of this study was to estimate the extent and characteristics of CAM use among cancer patients in Region Gävleborg.	Authentic
The activation of the phosphoinositide-3-kinase (PI3K)/AKT Serine/Threonine Kinase 1 (AKT)/mechanistic target of Rapamycin (mTOR) pathway is important in cancer tumorigenesis, progression and chemotherapy resistance.	Counterfeit
The LINC00958 overexpression significantly correlated with tumor size, lymph node status, TNM stage, and worse overall survival among NPC patients.	Counterfeit
Elevated cell purity and viability of CD4+ T cell were recorded as well as increases in microglia, however, there were reductions in the number of CD8+ T cells.	Counterfeit
These in vitro findings were detected in vivo on tumor formation in nude mice.	Counterfeit
Women ≥ 50 years old with a biopsy proven invasive cancer ≤ 10 mm were selected between October 2021 and November 2021 based on referrals and enrolled in this prospective study.	Authentic
Ewing sarcoma-associated transcript 1 (EWSAT1) has been reported to be a pivotal modulator in a series of cancers.	Counterfeit
The morphology of the hucMSC and hucMSC-exosomes (Exos) was identified.	Counterfeit
In this study, we identify special AT-rich-binding protein 2 (SATB2) as a new ΔNp63α-binding protein that is preferentially expressed in advanced-stage primary HNSCC and show that SATB2 promotes chemoresistance by enhancing ΔNp63α-mediated transrepression by augmenting ΔNp63α engagement to p53-family responsive elements.	Authentic
Renal tissues from RIRI mice showed lower miR-204-5p expression and higher Fas and FasL expression.	Counterfeit
Our results demonstrated that miRNA inhibitors specially targeting miR‑222 significantly suppressed cellular proliferation, migration, invasion and G1/S transition of the cell cycle, and induced cell apoptosis in HepG2 cells.	Counterfeit
The specific process includes case study and Q & A, which is intuitive and clear, and can enhance the comprehensive understanding of the theme.	Counterfeit
Tumor growth was assessed through xenografts in nude mice.	Counterfeit
Furthermore, AIMP2 inhibited intestinal organoid formation and growth by suppressing Wnt/β-catenin signaling in an Aimp2 gene dosage-dependent manner.	Authentic
Meanwhile, the targeting relationship between miR-183 and NR4A2 was validated by a bioinformatics website and dual-luciferase reporter gene assay.	Counterfeit
The survey data involves 31 provinces, 10 years, and 43 indicators, with a total of 43 × 10 × 31 = 13,330 data.	Counterfeit
Ribonucleic acid-sequencing (RNA-seq) data from breast cancer samples was used to identify an intronic start variant transcript of Acyl-CoA oxidase 2, ACOX2 (ACOX2-i9).	Authentic
Cancer-associated SPOP mutants often impair SPOP binding and polyubiquitination of its substrates to influence various cancer-relevant pathways, which include androgen/AR signaling, DNA repair and methylation, cellular stress surveillance, cancer metabolism, and immunity.	Authentic
Thus, the ability of physiologically relevant contexts to modulate canonical dependencies that are likely to be more complex has yet to be investigated systematically.	Authentic
To describe mechanisms behind and extent of overdetection in prostate cancer screening as well as possible ways to avoid unnecessary overdiagnosis.	Authentic
lncRNA TNRC6C-AS1 was highly expressed while STK4 was poorly expressed in TC tissues.	Counterfeit
After silencing of PVT1 or overexpressed miR-424-5p, decreased PVT1, CARM1, MMP-2, MMP-9, and Bcl-2 inhibited cell proliferation, migration, and invasion but promoted miR-424-5p, Bax, and cell apoptosis.	Counterfeit
Thus, negative regulators are required to maintain optimal levels of Wnt/β-catenin signaling.	Authentic
A critical benchmark in the development of antibody-based therapeutics is demonstration of efficacy in preclinical mouse models of human disease, many of which rely on immunodeficient mice.	Authentic
Of the studied tumour immunological markers, patients with liver metastases had low densities of CD3+ T cells (p = 0.030) and M1-like macrophages in their primary tumours (p = 0.025).	Authentic
The superior borders of the lesion, firmly attached to the roof of the third ventricle, required a careful evaluation.	Authentic
The aim was to analyse the ways in which various life situations and social relations shaped and limited the use of these strategies.	Authentic
Overall, our findings offer in vivo proofs that AEG-1 is essential for NF-κB activation and hepatocarcinogenesis, and they reveal new roles for AEG-1 in shaping the tumor microenvironment for HCC development.	Authentic
The cGMP/AGEs production levels were measured using enzyme-linked immunosorbent assay (ELISA) test.	Counterfeit
This study is intended to explore the correlation of IL-6 and JAK2/STAT3 signaling pathway with clinicopathological features and prognosis in nasopharyngeal carcinoma (NPC).	Counterfeit

The fourth factor is that cancer cells may be deficient in chromosome healing, the de novo addition of telomeres to the sites of DSBs, a mechanism that prevents chromosome instability resulting from DSBs near telomeres.

Authentic

MiR-182 functions as an anti-oncogene in ccRCC, and miR-182-mediated inhibition of cell migration and invasion might be through directly targeting IGF1R.

Counterfeit

In addition, circ_0061140 may enhance the proliferation rate and invasion ability of BCa cells through the modulation of microRNA-1236.

Counterfeit

The SCD1 mRNA level was detected by qPCR.

Counterfeit

Seven miRNAs, miR-21, miR-32, miR-99a, miR-99b, miR-148a, miR-221 and miR-590-5p, were found to be differentially expressed in CRPC compared with benign prostate hyperplasia (BPH) according to microarray analyses.

Authentic

Notably, rheumatic adverse events occurred at a higher rate (15.5%) than previously reported.

Authentic

Upregulated miR-132 or silenced PTEN activated the PI3K/Akt pathway, thus facilitating cardiocyte proliferation and repressing cardiocyte apoptosis and cardiac fibrosis, as well as inflammatory responses.

Counterfeit

Because mutations in these genes can compromise the efficacy of epidermal growth factor receptor blockade in CRC patients, identifying mutations that confer resistance to some targeted treatments may be useful to guide therapeutic decisions.

Authentic

Cancer Res; 76(8); 2288-300.

Authentic

Whole-brain radiation therapy, large tumors, young age at diagnosis, and male gender are risk factors for late cognitive sequelae after pediatric brain tumors.

Authentic

In the follow-up total cancer recurrence did not differ (P=0.187).

Authentic

EZH2 methylated STAT3 and enhanced STAT3 activity by increased tyrosine phosphorylation of STAT3, thereby increasing apoptosis and release of pro-inflammatory cytokines in ox-LDL-treated HUVECs.

Counterfeit

The regulatory effects of circ_0075825 and miR-432-5p on SOX9 protein expression were probed by western blot.

Counterfeit

In this study, 21 cases of large arterial blood vessel IS were analyzed by immunohistochemistry and fluorescence in situ hybridization and selectively by karyotyping, array comparative genomic hybridization, sequencing, phospho-kinase antibody arrays, and Western immunoblotting in search for novel diagnostic markers and potential molecular therapeutic targets.

Authentic

Although >85% of GIST patients treated with the small-molecule inhibitor imatinib mesylate (Gleevec) achieve disease stabilization, complete remissions are rare and a substantial proportion of patients develop resistance to imatinib over time.

Authentic

The current study provides evidence that LINC00922 acts as a tumor promoter by promoting NKD2 methylation.

Counterfeit

According to the COX regression analysis, MALAT1 expression, tumor size, and TNM stage were independent influencing factors of GBC patients' survival condition.

Counterfeit

The incidence of postoperative pain and discomfort in group B was lower than that in group A, and the difference between the two groups was statistically significant (P < 0.05); the incidence of postoperative chest pain, bleeding, pneumothorax, pulmonary infection, and atelectasis in group B was lower than that in group A, and the difference between the two groups was statistically significant (P < 0.05).

Counterfeit

Healthcare professionals need sufficient courage and willingness to share their patients' thoughts, beliefs, and grief to be able to guide patients toward improving their SWB.

Authentic

Five patients received computer-assisted dose-planned radiotherapy with curative intent (total dose 60-70.5 Gray), and two patients received radiotherapy as palliation.

Authentic

Plasma glucose, insulin, fructosamine, protein glycation, and blood glycated hemoglobin (HbA1C) were measured.

Counterfeit

Collectively, NAC could ameliorate COPD-induced pulmonary fibrosis by promoting immune response and inhibiting EMT process via the VWF/p38 MAPK axis, therefore providing us with a potential therapeutic target for treating COPD.

Counterfeit

We confirmed that miR-96-5p could directly target FOXF2 by luciferase reporter assay.

Counterfeit

In contrast, proliferating GNPs as well as MB and GBM express low or no ZNF238.

Authentic

The effects EBF1 gene and MAPK axis had on cell proliferation, apoptosis, and migration were determined by in vitro cell culturing.

Counterfeit

At visual evaluation, 13 of the HCC's were positive at PET-examination using FDG and 34 were positive using (11)C-acetate (p<0.001).

Authentic

Microarray-based gene expression profiling of AMI was conducted in order to identify differentially expressed genes (DEGs) and the corresponding miRs regulating these genes.

Counterfeit

miR-199a abrogated the protective effects of quercetin against hypoxia-elicited damages.

Counterfeit

Absent androgen receptor expression was associated with strong expression of chromogranin A (p = .02) and neuron specific enolase (p = .02), but not with focal expression of any marker.

Authentic

Gastric cancer tissues and corresponding adjacent normal tissues were extracted from patients.

Counterfeit

HF rats presented with downregulated expressions of Sirt1, brain-derived neurotrophic factor (BDNF) and exhibited upregulated expressions of NF-κB p65 and miR-155.

Counterfeit

The aim of the present study was to identify genes involved in hypoxia‑mediated responses to radiotherapy in HNSCC.

Authentic

The survey study, in turn, was based on earlier findings from a qualitative study of cancer patients in Sweden.

Authentic

Mean follow-up after VT was 95.0 months (range 26.5-182.4).

Authentic

Overexpression of miR-126 inhibited LP6 expression on mRNA and protein levels, and deactivate Wnt/β-catenin signaling pathway.

Counterfeit

ciRS-7 exerted influence on apoptosis, viability, migration, and tube formation through mediating PI3K/AKT and JNK/p38 pathways by miR-26a-5p downregulation in HMEC-1 cells.

Counterfeit

Icariin (ICA) is obtained from Epimedium brevicornu maxim and exploited to remedy miscellaneous cancers.

Counterfeit

Functional assays were utilized to test the inflammatory responses, oxidative stress, and pyroptosis using reverse transcription quantitative polymerase chain reaction, Western blotting, immunohistochemistry, immunofluorescence, and ELISA.

Counterfeit

MMP-13 and Col II expression in cartilage tissues was assessed; expression of β-catenin and Col2A1 in cartilage tissues was assessed.

Counterfeit

Entire 1992-1995 male (40,852) and female (39,420) birth cohorts were invited, and 11,662 males and 20,513 females vaccinated with 20-30% and 45% coverage in 2007-2010.

Authentic

Recent advances in the molecular characterization of bladder cancer have shown the potential role for DNA damage repair (DDR) gene alterations and molecular subtypes to guide therapy, but these need validation from prospective clinical trials.

Authentic

Bladder cancer (BCa) is a heterogeneous disease that poses great threats on public health.

Counterfeit

MicroRNAs (miRNAs) as central regulators have been discovered in colon cancer.

Counterfeit

Expression of IL-1β, miR-9-5p, TPX2, amyloid-β (Aβ) and p-tau in mouse hippocampal tissues was determined.

Counterfeit

The automated Ki-67 assessment method appears to be comparable to the visual method in synovial sarcoma and had a significant association to overall survival.

Authentic

ARF inhibits nucleolar import of TTF-I by binding to this nucleolar localization sequence, causing the accumulation of TTF-I in the nucleoplasm.

Authentic

In vitro results were reproduced in in vivo experiments.

Counterfeit

Hence, this study investigated the role of HNF1A-AS1 in angiogenesis of colon cancer.

Counterfeit

Our study reveals a new molecular mechanism of Coronin 3 in promoting glioma growth and development through regulating the Wnt/β-catenin signaling pathway.

Counterfeit

Additionally, the aim was to compare SF SP and PGE2 between osteoarthritic and non-osteoarthritic joints, and investigate associations between SP, PGE2, osteoarthritic pain, and the signalment of dogs.

Authentic

Cancer and non-tumoral tissues were collected, in which HEIH, miR-185 and KLK5 expression were detected, as well as their correlations.

Counterfeit

Gross total resection (GTR) was achieved in 118 patients and 5-year overall survival for patients with GTR versus those with non-GTR differed significantly with 64% versus 22%.

Authentic

Our results revealed that mice with I/R-induced hepatic injury showed higher serum levels of blood glucose, lipids, ALT and AST and leukaemia inhibitory factor (LIF) expression, and lower HIF1α and ZEB1 expression (P < .05), which were reversed after remifentanil treatment (P < .05).

Counterfeit

Compared with the control group, protein expressions of VEGF, NF-κB, p-IκB/IκB, expression of ANRIL, and mRNA expressions of VEGF, FLT-1 and NF-κB were increased in the DM + CI group.

Counterfeit

Regarding the mechanism, PTPRG-AS1 could serve as a competing endogenous RNA in EOC cells by decoying microRNA-545-3p (miR-545-3p), thereby elevating histone deacetylase 4 (HDAC4) expression.

Counterfeit

Recently, the long noncoding RNAs (lncRNAs) have been demonstrated to be involved in the development of various renal diseases.

Counterfeit

To achieve the measured variability, one is necessarily led to assume a wide variation from patient to patient of the sensitive cells' response to the therapy.

Authentic

Together, these findings establish that Gd-DTPA-based DCE-MRI can noninvasively visualize tumor IFP, and they reveal the potential for v(0) determined by this method to serve as a novel general biomarker of tumor aggressiveness.

Authentic

These data provided strong evidence that miR-130a may be involved in the progression of OSAHS-associated PHT by down-regulating GAX gene.

Counterfeit

We found that IL-1β induced a significantly inflammatory injury in CHON-001 cells.

Counterfeit

Transient activation of ER stress with carbon monoxide drives mitochondrial biogenesis and protective autophagy that elicits superior antitumor T-cell function, revealing an approach to improving adoptive cell efficacy therapy.

Authentic

Thus, experiments were designed to test the hypothesis that HBx triggers malignant transformation by promoting properties that are characteristic of cancer stem cells (CSC).

Authentic

Overexpression of LINC00261 inhibited prostate cancer cells proliferation, migration, and invasion as well as angiogenesis, which could be reversed by silencing DKK3.

Counterfeit

MTDH overexpression in MKN45 cells increased the levels of P-glycoprotein (P-gp) and promoted 5-FU resistance, while inhibition of MTDH showed the opposite result.

Counterfeit

Compared to controls, the tumor area in zebrafish treated with bilberry powder (10 and 25 µg/mL) was reduced significantly (p = 0.038 and p = 0.021, respectively), but the number of fish with metastases did not differ between groups.

Authentic

Hdac3 augmented the recruitment of p65 in the Pgf promoter region through the miR-17/EZH1 axis, thus enhancing the transcription and expression of Pgf, which elicited abnormal angiogenesis and alveolarization of BPD mice.

Counterfeit

Background: Histone H1.5 has been considered as a novel cancer marker as its expression is associated with various human cancers.

Counterfeit

This modernization brings about other forms of physical education, being student centered and more interactive.

Counterfeit

However, the receptor-signal transduction was silenced, revealing no Ca(2+) mobilization or cell-cycle entry, while phosphorylated extracellular-regulated kinase 1/2 basal levels were high and could not be elevated further by oxidized low-density lipoprotein.

Authentic

Bioinformatics analysis showed a targeting relationship between miR-205 and the 3'-UTR of YAP1.

Counterfeit

The aim of this study was to estimate the extent and characteristics of CAM use among cancer patients in Region Gävleborg.

Authentic

The activation of the phosphoinositide-3-kinase (PI3K)/AKT Serine/Threonine Kinase 1 (AKT)/mechanistic target of Rapamycin (mTOR) pathway is important in cancer tumorigenesis, progression and chemotherapy resistance.

Counterfeit

The LINC00958 overexpression significantly correlated with tumor size, lymph node status, TNM stage, and worse overall survival among NPC patients.

Counterfeit

Elevated cell purity and viability of CD4+ T cell were recorded as well as increases in microglia, however, there were reductions in the number of CD8+ T cells.

Counterfeit

These in vitro findings were detected in vivo on tumor formation in nude mice.

Counterfeit

Women ≥ 50 years old with a biopsy proven invasive cancer ≤ 10 mm were selected between October 2021 and November 2021 based on referrals and enrolled in this prospective study.

Authentic

Ewing sarcoma-associated transcript 1 (EWSAT1) has been reported to be a pivotal modulator in a series of cancers.

Counterfeit

The morphology of the hucMSC and hucMSC-exosomes (Exos) was identified.

Counterfeit

In this study, we identify special AT-rich-binding protein 2 (SATB2) as a new ΔNp63α-binding protein that is preferentially expressed in advanced-stage primary HNSCC and show that SATB2 promotes chemoresistance by enhancing ΔNp63α-mediated transrepression by augmenting ΔNp63α engagement to p53-family responsive elements.

Authentic

Renal tissues from RIRI mice showed lower miR-204-5p expression and higher Fas and FasL expression.

Counterfeit

Our results demonstrated that miRNA inhibitors specially targeting miR‑222 significantly suppressed cellular proliferation, migration, invasion and G1/S transition of the cell cycle, and induced cell apoptosis in HepG2 cells.

Counterfeit

The specific process includes case study and Q & A, which is intuitive and clear, and can enhance the comprehensive understanding of the theme.

Counterfeit

Tumor growth was assessed through xenografts in nude mice.

Counterfeit

Furthermore, AIMP2 inhibited intestinal organoid formation and growth by suppressing Wnt/β-catenin signaling in an Aimp2 gene dosage-dependent manner.

Authentic

Meanwhile, the targeting relationship between miR-183 and NR4A2 was validated by a bioinformatics website and dual-luciferase reporter gene assay.

Counterfeit

The survey data involves 31 provinces, 10 years, and 43 indicators, with a total of 43 × 10 × 31 = 13,330 data.

Counterfeit

Ribonucleic acid-sequencing (RNA-seq) data from breast cancer samples was used to identify an intronic start variant transcript of Acyl-CoA oxidase 2, ACOX2 (ACOX2-i9).

Authentic

Cancer-associated SPOP mutants often impair SPOP binding and polyubiquitination of its substrates to influence various cancer-relevant pathways, which include androgen/AR signaling, DNA repair and methylation, cellular stress surveillance, cancer metabolism, and immunity.

Authentic

Thus, the ability of physiologically relevant contexts to modulate canonical dependencies that are likely to be more complex has yet to be investigated systematically.

Authentic

To describe mechanisms behind and extent of overdetection in prostate cancer screening as well as possible ways to avoid unnecessary overdiagnosis.

Authentic

lncRNA TNRC6C-AS1 was highly expressed while STK4 was poorly expressed in TC tissues.

Counterfeit

After silencing of PVT1 or overexpressed miR-424-5p, decreased PVT1, CARM1, MMP-2, MMP-9, and Bcl-2 inhibited cell proliferation, migration, and invasion but promoted miR-424-5p, Bax, and cell apoptosis.

Counterfeit

Thus, negative regulators are required to maintain optimal levels of Wnt/β-catenin signaling.

Authentic

A critical benchmark in the development of antibody-based therapeutics is demonstration of efficacy in preclinical mouse models of human disease, many of which rely on immunodeficient mice.

Authentic

Of the studied tumour immunological markers, patients with liver metastases had low densities of CD3+ T cells (p = 0.030) and M1-like macrophages in their primary tumours (p = 0.025).

Authentic

The superior borders of the lesion, firmly attached to the roof of the third ventricle, required a careful evaluation.

Authentic

The aim was to analyse the ways in which various life situations and social relations shaped and limited the use of these strategies.

Authentic

Overall, our findings offer in vivo proofs that AEG-1 is essential for NF-κB activation and hepatocarcinogenesis, and they reveal new roles for AEG-1 in shaping the tumor microenvironment for HCC development.

Authentic

The cGMP/AGEs production levels were measured using enzyme-linked immunosorbent assay (ELISA) test.

Counterfeit

This study is intended to explore the correlation of IL-6 and JAK2/STAT3 signaling pathway with clinicopathological features and prognosis in nasopharyngeal carcinoma (NPC).

Counterfeit