{{위키데이터 속성 추적}}
{{chembox
| Watchedfields = changed
| verifiedrevid = 477238648
| Name = 아세트아닐리드
| ImageFile = Acetanilid.svg
| ImageSize = 170
| ImageFileL1 = Acetanilide Ball and Stick.png
| ImageSizeL1 = 130
| ImageFileR1 = Acetanilide Space Fill.png
| ImageSizeR1 = 130
| ImageName = Acetanilide
| PIN = ''N''-Phenylacetamide<ref name=iupac2013>{{서적 인용| title =  Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book) | publisher = [[Royal Society of Chemistry|The Royal Society of Chemistry]] | date = 2014 | location = Cambridge | page = 846 | doi = 10.1039/9781849733069-FP001 | isbn = 978-0-85404-182-4 | quote = ''N''-Phenyl derivatives of primary amides are called ‘anilides’ and may be named using the term ‘anilide’ in place of ‘amide’ in systematic or retained names of amides. (…) However, names expressing ''N''-substitution by a phenyl group on an amide are preferred IUPAC names.| chapter = Front Matter }}</ref>
| OtherNames = Acetanilide<ref name=iupac2013/><br />''N''-Phenylethanamide
|Section1={{Chembox Identifiers
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = SP86R356CC
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = C07565
| Beilstein = 606468
| Gmelin = 82833
| InChI = 1/C8H9NO/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)
| InChIKey = FZERHIULMFGESH-UHFFFAOYAA
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 269644
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C8H9NO/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = FZERHIULMFGESH-UHFFFAOYSA-N
| CASNo = 103-84-4
| CASNo_Ref = {{cascite|correct|CAS}}
| EC_number = 203-150-7
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 880
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 28884
| PubChem = 904
| RTECS = AD7350000
| SMILES = O=C(Nc1ccccc1)C
}}
|Section2={{Chembox Properties
| Properties_ref =<ref>{{RubberBible62nd|page=C-67}}.</ref><ref name="SIDS">{{SIDS-ref | title = Acetanilide | id = Acetanilide | date = September 2003}}.</ref>
| C=8 | H=9 | N=1 | O=1
| Odor = Odorless
| Density = 1.219 g/cm<sup>3</sup>
| MeltingPtC = 113-115
| BoilingPtC = 304
| Dipole = 2.71
| Solubility = <0.56 g/100 mL (25 °C)
| SolubleOther = Soluble in [[ethanol]], [[diethyl ether]], [[acetone]], [[benzene]]
| LogP = 1.16 (23 °C)
| VaporPressure = 2 Pa (20 °C)
| pKa = 0.5 (25 °C, H<sub>2</sub>O) (conjugate acid)<ref name="CRC97">{{서적 인용| editor= Haynes, William M. | year = 2016 | title = CRC Handbook of Chemistry and Physics | edition = 97th | publisher = [[CRC Press]] | isbn = 9781498754293 | pages=5–88 | title-link = CRC Handbook of Chemistry and Physics }}</ref>}}
|Section7={{Chembox Hazards
| Hazards_ref =<ref>{{인용|title=HSNO Chemical Classification Information Database |url=http://www.ermanz.govt.nz/Chemicals/ChemicalDisplay.aspx?SubstanceID=12901 |publisher=New Zealand Environmental Risk Management Authority |access-date=2009-08-26 }}{{깨진 링크|date=June 2017 |bot=InternetArchiveBot |fix-attempted=yes }}.</ref><ref name="MSDS">{{인용| url = http://ptcl.chem.ox.ac.uk/MSDS/AC/acetanilide.html | archive-url = https://web.archive.org/web/20020623073536/http://ptcl.chem.ox.ac.uk/MSDS/AC/acetanilide.html | url-status = dead | archive-date = 2002-06-23 | title = Safety data for acetanilide | publisher = Physical Chemistry Laboratory, University of Oxford }}.</ref>
| ExternalSDS = [http://physchem.ox.ac.uk/MSDS/AC/acetanilide.html External MSDS]
| GHSPictograms = {{GHS exclamation mark|Acute Tox. (oral) 4}}
| GHSSignalWord = WARNING
| HPhrases = {{H-phrases|302}}
| PPhrases = {{P-phrases|264|270|301+312|330|501}}
| FlashPtC = 174
| AutoignitionPtC = 545
  }}
}}

'''아세트아닐리드'''(Acetanilide)는 잎 모습을 보이는 무취의 [[고체]] 화학 물질이다. 한때 안티페브린(Antifebrin)이라는 [[상호]]명으로 알려진 물질이다.

== 생성 ==
아세트아닐리드는 [[아세트산 무수물]]을 [[아닐린]]과 반응시켜 만들 수 있다.
:C<sub>6</sub>H<sub>5</sub>NH<sub>2</sub> + (CH<sub>3</sub>CO)<sub>2</sub>O → C<sub>6</sub>H<sub>5</sub>NHCOCH<sub>3</sub> + CH<sub>3</sub>COOH

== 용도 ==
아세트아닐리드는 [[과산화 수소]] 분해 [[억제제]]로서 사용되며 [[셀룰로스]] [[에스터]] [[바니시]]를 안정시키기 위해 사용한다.
=== 의료 목적 ===
아세트아닐라이드는 [[진통제]] 및 [[해열제]] 속성을 보유한 것으로 알려진 최초의 [[아닐린]] 파생물이며 1886년 A. 칸과 P. 헤프에 의해 '안티페브린'이라는 이름으로 의료용으로 빠르게 도입되었다.<ref>{{인용| last1 = Cahn | first1 = A. | last2 = Hepp | first2 = P. | title = Das Antifebrin, ein neues Fiebermittel | journal = Centralbl. Klin. Med. | year = 1886 | volume = 7 | pages = 561–64}}.</ref> 그러나 수용 불가능한 독성 효과([[청색증]] 등을 일으킬 수 있음)가 있고 궁극적으로 간과 장기를 손상시킬 수 있어서 [[페나세틴]] 등 독성이 덜한 것으로 추정되는 아닐린 파생물을 조속히 구하기에 이르렀다.

== 각주 ==
{{각주}}

{{전거 통제}}

[[분류:아세트아닐라이드]]
[[분류:시장에서 철퇴된 약]]