{{위키데이터 속성 추적}}
{{Chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 428833652
| Name = 도코사테트라엔산
| ImageFile = adrenic acid.png
| ImageSize = 200px
| IUPACName = 7''Z'',10''Z'',13''Z'',16''Z''-docosatetraenoic acid
| OtherNames =
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo = 28874-58-0
| PubChem = 5497181
| SMILES = OC(CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 4593749
| InChI = 1/C22H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,23,24)/b7-6-,10-9-,13-12-,16-15-
| InChIKey = TWSWSIQAPQLDBP-DOFZRALJBY
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C22H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,23,24)/b7-6-,10-9-,13-12-,16-15-
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = TWSWSIQAPQLDBP-DOFZRALJSA-N
}}
|Section2={{Chembox Properties
| Formula = C<sub>22</sub>H<sub>36</sub>O<sub>2</sub>
| MolarMass = 332.5 g/mol
| Appearance = 
| Density = 
| MeltingPt = 
| BoilingPt = 
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards = 
| FlashPt = 
| AutoignitionPt = }}
}}
'''도코사테트라엔산'''({{llang|en|docosatetraenoic acid}})은 곧은 사슬의 22:4 [[지방산]]을 지칭한다.

다음과 같은 한 가지 이성질체가 특히 관심의 대상이다.
* 올-시스-7,10,13,16-도코사테트라엔산은 [[일반명]]이 '''아드렌산'''({{llang|en|adrenic acid}})인 [[오메가-6 지방산]]이다. 아드렌산은 [[아라키돈산]]이 2개의 [[탄소]] 사슬만큼 신장되어 형성된 자연에서 생성되는 [[다불포화 지방산]]이다. 아드렌산은 초기 사람의 [[뇌]]에서 가장 풍부한 지방산 중 하나이다.<ref name=Martinez >{{저널 인용|author=Martinez M |title=Tissue levels of polyunsaturated fatty acids during early human development |journal=J Pediatr |volume=120 |issue=4 Pt 2 |pages=S129–38 |year=1992 |pmid=1532827 |doi=10.1016/S0022-3476(05)81247-8}}</ref> 이러한 [[불포화 지방산]]은 또한 [[세포]]에 의해 생물학적 활성 산물, 즉 다이호모프로스타글란딘<ref name=Campbell>{{저널 인용|vauthors=Campbell WB, Falck JR, Okita JR, Johnson AR, Callahan KS |title=Synthesis of dihomoprostaglandins from adrenic acid (7,10,13,16-docosatetraenoic acid) by human endothelial cells |journal=Biochim. Biophys. Acta |volume=837 |issue=1 |pages=67–76 |year=1985 |pmid=3931686 |doi=10.1016/0005-2760(85)90086-4}}</ref> 및 다이호모-에폭시에이코사트라이엔산<ref name="pmid20038752">{{저널 인용| vauthors = Kopf PG, Zhang DX, Gauthier KM, Nithipatikom K, Yi XY, Falck JR, Campbell WB | title = Adrenic acid metabolites as endogenous endothelium-derived and zona glomerulosa-derived hyperpolarizing factors | journal = Hypertension | volume = 55 | issue = 2 | pages = 547–54 | year = 2010 | pmid = 20038752 | pmc = 2819927 | doi = 10.1161/HYPERTENSIONAHA.109.144147 | url = }}</ref>으로 대사된다.<ref name="Yi">{{저널 인용|journal=Am J Physiol Heart Circ Physiol|date=May 2007|volume=292|issue=5|pages=H2265–74|title=Metabolism of adrenic acid to vasodilatory 1alpha,1beta-dihomo-epoxyeicosatrienoic acids by bovine coronary arteries.|vauthors=Yi XY, Gauthier KM, Cui L, Nithipatikom K, Falck JR, Campbell WB|pmid=17209008|doi=10.1152/ajpheart.00947.2006}}<!--|accessdate=2007-10-30 --></ref>

== 같이 보기 ==
* [[다불포화 지방산]]
* [[오메가-6 지방산]]
* [[도코사노이드]]

== 각주 ==
{{각주}}

== 더 읽을거리 ==
* Ferretti, A., Flanagan, V.P. Mass spectrometric evidence for the conversion of exogenous adrenate to dihomo-prostaglandins by seminal vesicle cyclo-oxygenase. A comparative study of two animal species. J Chromatogr 383 241-250 (1986).
* Sprecher, H., VanRollins, M., Sun, F., et al. Dihomo-prostaglandins and -thromboxane. A prostaglandin family from adrenic acid that may be preferentially synthesized in the kidney. J Biol Chem 257 3912-3918 (1982).

{{지방산}}
{{전거 통제}}

[[분류:지방산]]
[[분류:알켄산]]