{{위키데이터 속성 추적}}
{{Infobox medical condition (new)
| name            = 부신피질암
| synonyms        = Adrenocortical carcinoma, Adrenal cortical carcinoma, adrenocorticocarcinoma, adrenal cortical cancer, adrenal cortex cancer
| image           = Adrenal cortical carcinoma - low mag.jpg
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| field           = [[종양학]]
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'''부신피질암'''(Adrenocortical carcinoma, ACC)은 [[부신겉질]]([[스테로이드 호르몬]] 생성 조직)에서 발생하는 공격적인 [[암]]이다.

부신피질암은 쿠싱 증후군, 콘 증후군, 남성화 및 여성화를 포함하여 스테로이드 호르몬 생성("기능적") 종양을 가진 환자에서 발생할 수 있는 많은 호르몬 증후군에 대해 주목할 만하다. 부신피질암은 진단 당시 주변 조직을 침범하거나 먼 장기로 전이하는 경우가 많으며, 전체 5년 생존율은 약 50%이다.<ref name="CancerNet">{{웹 인용|url=https://www.cancer.net/cancer-types/adrenal-gland-tumor/statistics|title=Adrenal Gland Tumor: Statistics|website=Cancer.net|date=25 June 2012 |access-date=2020-07-01}}</ref>

부신피질암은 1년에 인구 100만 명당 1~2명이 발생하는 희귀 종양이다.<ref>{{저널 인용| vauthors = Wang C, Sun Y, Wu H, Zhao D, Chen J | title = Distinguishing adrenal cortical carcinomas and adenomas: a study of clinicopathological features and biomarkers | journal = Histopathology | volume = 64 | issue = 4 | pages = 567–576 | date = March 2014 | pmid = 24102952 | pmc = 4282325 | doi = 10.1111/his.12283 }}</ref><ref>{{저널 인용| vauthors = Fassnacht M, Dekkers OM, Else T, Baudin E, Berruti A, de Krijger R, Haak HR, Mihai R, Assie G, Terzolo M | display-authors = 6 | title = European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors | language = en-US | journal = European Journal of Endocrinology | volume = 179 | issue = 4 | pages = G1–G46 | date = October 2018 | pmid = 30299884 | doi = 10.1530/EJE-18-0608 | doi-access = free }}</ref><ref>{{저널 인용| vauthors = Fassnacht M, Terzolo M, Allolio B, Baudin E, Haak H, Berruti A, Welin S, Schade-Brittinger C, Lacroix A, Jarzab B, Sorbye H, Torpy DJ, Stepan V, Schteingart DE, Arlt W, Kroiss M, Leboulleux S, Sperone P, Sundin A, Hermsen I, Hahner S, Willenberg HS, Tabarin A, Quinkler M, de la Fouchardière C, Schlumberger M, Mantero F, Weismann D, Beuschlein F, Gelderblom H, Wilmink H, Sender M, Edgerly M, Kenn W, Fojo T, Müller HH, Skogseid B | display-authors = 6 | title = Combination chemotherapy in advanced adrenocortical carcinoma | journal = The New England Journal of Medicine | volume = 366 | issue = 23 | pages = 2189–2197 | date = June 2012 | pmid = 22551107 | doi = 10.1056/NEJMoa1200966 | doi-access = free }}</ref><ref name="DeVita">{{서적 인용|title=Cancer: principles & practice of oncology|publisher=Lippincott-Raven|year=2005|isbn=978-0-7817-4865-0| veditors = DeVita VT, Hellman S, Rosenberg SA |location=Philadelphia}}</ref><ref name="UTDACC">{{웹 인용|url= http://www.uptodateonline.com/utd/content/topic.do?topicKey=adrenal/17707&type=A&selectedTitle=1~16 |title= Clinical presentation and evaluation of adrenocortical tumors| vauthors = Savarese DM, Nieman LK |date=2006-08-08|website=UpToDate Online v. 15.1 |publisher=UpToDate |access-date=2007-06-05 |archive-url= https://web.archive.org/web/20070929002439/http://www.uptodateonline.com/utd/content/topic.do?topicKey=adrenal%2F17707&type=A&selectedTitle=1~16|archive-date=2007-09-29 |url-status=dead}}</ref> 5세 미만의 어린이와 30~40세의 성인에서 집단적으로 발생하는 이봉 분포(bimodal distribution)를 보이고 있다.<ref name="DeVita" /> 널리 사용되는 안지오텐신-II 반응성 스테로이드 생성 세포주 H295R은 원래 부신피질암으로 진단된 종양에서 분리되었다.<ref name="TP-160129-001">{{저널 인용| vauthors = Wang T, Rainey WE | title = Human adrenocortical carcinoma cell lines | journal = Molecular and Cellular Endocrinology | volume = 351 | issue = 1 | pages = 58–65 | date = March 2012 | pmid = 21924324 | pmc = 3288152 | doi = 10.1016/j.mce.2011.08.041 }}</ref><ref name="TP-150519-002">{{저널 인용| vauthors = Gazdar AF, Oie HK, Shackleton CH, Chen TR, Triche TJ, Myers CE, Chrousos GP, Brennan MF, Stein CA, La Rocca RV | display-authors = 6 | title = Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis | journal = Cancer Research | volume = 50 | issue = 17 | pages = 5488–5496 | date = September 1990 | pmid = 2386954 | url = http://cancerres.aacrjournals.org/content/50/17/5488.long }}</ref>

== 각주 ==
{{각주}}

== 외부 링크 ==
{{Medical resources
|  DiseasesDB      =
|  ICD10           = {{ICD10|C|74|0|c|73}}
|  ICD9            = {{ICD9|194}}
|  ICDO            = {{ICDO|8370|3}}
|  OMIM            = 202300
|  MedlinePlus     = 001663
|  eMedicineSubj   = ped
|  eMedicineTopic  = 41
|  MeshID          = D018268
|  Orphanet        = 1501
}}

[[분류:희귀암]]
[[분류:부신 질환]]
[[분류:내분비 신생물]]