{{위키데이터 속성 추적}}
{{chembox
| Verifiedfields = changed
| Watchedfields  = changed
| verifiedrevid  = 464381006
| Name           = Resiniferatoxin
| ImageFile      = Resiniferatoxin.svg
| ImageSize      = 200px
| ImageName      = 
| OtherNames     = 
| IUPACName      = [(1''R'',2''R'',6''R'',10''S'',11''R'',13''R'',15''R'',17''R'')-13-Benzyl-6-hydroxy-4,17-dimethyl-5-oxo-15-(prop-1-en-2-yl)-12,14,18-trioxapentacyclo[11.4.1.0<sup>1,10</sup>.0<sup>2,6</sup>.0<sup>11,15</sup>]octadeca-3,8-dien-8-yl]methyl 2-(4-hydroxy-3-methoxyphenyl)acetate
| SystematicName = 
| Section1       = {{Chembox Identifiers
| IUPHAR_ligand = 2491
| SMILES = C[C@@H]1C[C@]2([C@H]3[C@H]4[C@]1([C@@H]5C=C(C(=O)[C@]5(CC(=C4)COC(=O)Cc6ccc(c(c6)OC)O)O)C)O[C@](O3)(O2)Cc7ccccc7)C(=C)C
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35-,36-,37-/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = DSDNAKHZNJAGHN-MXTYGGKSSA-N
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 57444-62-9
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = A5O6P1UL4I
|   ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID=4642871  
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 448382
|   PubChem = 104826
|   MeSHName = resiniferatoxin   }}
| Section2       = {{Chembox Properties
|   C=37|H=40|O=9
|   Density = 1.35 ± 0.1 g/cm<sup>3</sup>
|   Solubility = insoluble in water and hexane, soluble in ethyl acetate, ethanol, methanol, acetone, chloroform, and dichloromethane. 
  }}
| Section3       = 
| Section4       = 
| Section5       = 
| Section6       = 
}}

'''레시니페라톡신'''(Resiniferatoxin, RTX)은 [[모로코]]에서 발견되는 [[선인장]] 식물 [[유포르비아 레시니페라]]에서 자연적으로 볼 수 있는 화학 물질이며, 1~5mg만 섭취하더라도 치명적인 몸 손상을 받을 수 있는 독극물이다. [[나이지리아]] 북부 [[유포르비아 포이소이]]에서도 발견된다.<ref name="BoDD">[http://www.botanical-dermatology-database.info/BotDermFolder/EUPH-9.html#Euphorbia%20poissonii ''Euphorbia poissonii''] in BoDD – Botanical Dermatology Database</ref> [[캡사이신]]의 강력한 [[기능 유사체]]로서 [[고추]]의 유효 성분이다.<ref name=Walpole>{{저널 인용| author=Christopher S. J. Walpole| title=Similarities and Differences in the Structure-Activity Relationships of Capsaicin and Resiniferatoxin Analogues  | journal=J. Med. Chem.  | year=1996 | volume=39 | pages=2939–2952 | doi=10.1021/jm960139d | pmid=8709128 | issue=15|display-authors=etal}}</ref>

레시니페라톡신은 160억 [[스코빌 척도]] 점수를 받았으며 이는 순수 [[캡사이신]] 대비 약 500~1000배 더 매운 편에 속한다.<ref>National Institutes of Health, Clinical Center Department of Perioperative Medicine [https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2667622 Chemical from cactus-like plant shows promise in controlling surgical pain, while leaving touch and coordination intact, rat study shows] News release December 21, 2017, retrieved 28 February 2018.</ref><ref name="QUE">{{서적 인용| last1 = Ellsworth | last2 = Wein | first1 = Pamela | first2 = Alan J. | date = 2009 | title = Questions and Answers about Overactive Bladder | publisher = Jones & Bartlett Learning | pages = 97–100 | isbn = 978-1449631130|url=https://books.google.com/books?id=4WhpvPMZOJUC}}</ref>

== 각주 ==
{{각주}}

== 외부 링크 ==
{{위키공용분류}}
* [https://www.seattlepi.com/lifestyle/health/article/Fiery-pepper-may-hold-key-to-easing-pain-1192896.php Fiery pepper may hold key to easing pain] Lauran Neergaard, [[AP (통신사)|The Associated Press]] Published 10:00 pm PST, Monday, January 16, 2006
* {{PubChem|Resiniferatoxin}}

{{전거 통제}}

[[분류:신경독]]
[[분류:식물 독소]]
[[분류:진통제]]
[[분류:터펜류]]
[[분류:카복실산 에스터]]
[[분류:사이클로펜텐]]
[[분류:전합성]]