{{위키데이터 속성 추적}}
{{유전자 정보}}
'''막 횡단 단백질 분해 효소, 세린 6''' 또는 '''매트립테이스-2'''(Transmembrane protease, serine 6 또는 matriptase-2)는 인간에서 ''TMPRSS6'' [[유전자|유전자에]] 의해 암호화되는 [[효소]]이다.<ref name="entrez">{{웹 인용|url=https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=164656|제목=Entrez Gene: TMPRSS6 transmembrane protease, serine 6|확인날짜=}}</ref>

이 유전자에 의해 암호화된 단백질은 세포 표면에 부착된 것으로 발견되는 II 형 막 횡단 세린 단백질 분해 효소이다. 암호화된 단백질은 간에서의 매트릭스 리모델링 과정에 관여 할 수 있다.<ref name="entrez">{{웹 인용|url=https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=164656|제목=Entrez Gene: TMPRSS6 transmembrane protease, serine 6|확인날짜=}}</ref>

== 각주 ==
{{각주}}

== 추가 자료 ==
{{참고 자료 시작|2}}
*{{저널 인용|제목=Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer|저널=Cancer Metastasis Rev.|연도=2004|권=22|호=2–3|쪽=237–58|doi=10.1023/A:1023003616848|pmid=12784999}}
*{{저널 인용|제목=The type II transmembrane serine protease matriptase-2--identification, structural features, enzymology, expression pattern and potential roles|저널=Front. Biosci.|연도=2007|권=13|호=13|쪽=569–79|doi=10.2741/2702|pmid=17981570}}
*{{저널 인용|제목=The DNA sequence of human chromosome 22|저널=Nature|연도=1999|권=402|호=6761|쪽=489–95|doi=10.1038/990031|pmid=10591208}}
*{{저널 인용|제목=Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins|저널=J. Biol. Chem.|연도=2002|권=277|호=40|쪽=37637–46|doi=10.1074/jbc.M203007200|pmid=12149247}}
*{{저널 인용|제목=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences|저널=Proc. Natl. Acad. Sci. U.S.A.|연도=2003|권=99|호=26|쪽=16899–903|doi=10.1073/pnas.242603899|pmc=139241|pmid=12477932}}
*{{저널 인용|제목=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment|저널=Genome Res.|연도=2003|권=13|호=10|쪽=2265–70|doi=10.1101/gr.1293003|pmc=403697|pmid=12975309}}
*{{저널 인용|제목=Complete sequencing and characterization of 21,243 full-length human cDNAs|저널=Nat. Genet.|연도=2004|권=36|호=1|쪽=40–5|doi=10.1038/ng1285|pmid=14702039}}
*{{저널 인용|제목=A genome annotation-driven approach to cloning the human ORFeome|저널=Genome Biol.|연도=2005|권=5|호=10|쪽=R84|doi=10.1186/gb-2004-5-10-r84|pmc=545604|pmid=15461802}}
*{{저널 인용|제목=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)|저널=Genome Res.|연도=2004|권=14|호=10B|쪽=2121–7|doi=10.1101/gr.2596504|pmc=528928|pmid=15489334}}
*{{저널 인용|제목=Towards a proteome-scale map of the human protein-protein interaction network|저널=Nature|연도=2005|권=437|호=7062|쪽=1173–8|doi=10.1038/nature04209|pmid=16189514}}
*{{저널 인용|제목=Refinement of the 22q12-q13 breast cancer--associated region: evidence of TMPRSS6 as a candidate gene in an eastern Finnish population|저널=Clin. Cancer Res.|연도=2006|권=12|호=5|쪽=1454–62|doi=10.1158/1078-0432.CCR-05-1417|pmid=16533768}}
*{{저널 인용|제목=Matriptase-2 inhibits breast tumor growth and invasion and correlates with favorable prognosis for breast cancer patients|저널=Clin. Cancer Res.|연도=2007|권=13|호=12|쪽=3568–76|doi=10.1158/1078-0432.CCR-06-2357|pmid=17575220}}
{{참고 자료 끝}}

[[분류:인간 22번 염색체상 유전자]]