{{위키데이터 속성 추적}}
{{Drugbox|drug_name=|KEGG=D10624|CAS_number=1338225-97-0|CAS_supplemental=|PubChem=58460047|IUPHAR_ligand=|DrugBank=DB12301|ChEBI_Ref={{ebicite|correct|EBI}}|ChEBI=|ChemSpiderID=28424197|UNII_Ref={{fdacite|correct|FDA}}|UNII=913P6LK81M|ChEMBL=2364608|elimination_half-life=|PDB_ligand=2KW|synonyms=MK-1439

<!-- Chemical data -->|IUPAC_name=3-Chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1''H''-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydro-3-pyridinyl}oxy)benzonitrile|C=17|H=11|Cl=1|F=3|N=5|O=3|smiles=Cn1c(n[nH]c1=O)Cn2ccc(c(c2=O)Oc3cc(cc(c3)Cl)C#N)C(F)(F)F|StdInChI=1S/C17H11ClF3N5O3/c1-25-13(23-24-16(25)28)8-26-3-2-12(17(19,20)21)14(15(26)27)29-11-5-9(7-22)4-10(18)6-11/h2-6H,8H2,1H3,(H,24,28)|excretion=<!--Identifiers -->|metabolism=|image=Doravirine structure.svg|ATC_prefix=J05|alt=|caption=<!-- Clinical data -->|tradename=Pifeltro|Drugs.com={{drugs.com|monograph|doravirine}}|MedlinePlus=a618048|DailyMedID=Doravirine|pregnancy_AU=<!-- A / B1 / B2 / B3 / C / D / X -->|pregnancy_category=|routes_of_administration=[[Oral administration|By mouth]]<ref name="Pifeltro FDA label" >{{웹 인용| title=Pifeltro- doravirine tablet, film coated | website=DailyMed | date=10 October 2019 | url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=76ce1f00-28c0-4314-bd2c-d473fe3d0970 | access-date=22 September 2020}}</ref><ref>{{웹 인용| vauthors = Collins S, Horn T |title=The Antiretroviral Pipeline.|url=http://www.pipelinereport.org/sites/g/files/g575521/f/201509/ARV.pdf|website=Pipeline Report|access-date=6 December 2015|page=10|url-status=dead|archive-url=https://web.archive.org/web/20160311235843/http://www.pipelinereport.org/sites/g/files/g575521/f/201509/ARV.pdf|archive-date=11 March 2016}}</ref>|ATCvet=|ATC_suffix=AG06|protein_bound=|ATC_supplemental=|legal_AU=S4|legal_CA=<!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->|legal_UK=POM|legal_UK_comment=<ref>{{웹 인용| title=Pifeltro 100 mg film-coated tablets - Summary of Product Characteristics (SmPC) | website=(emc) | url=https://www.medicines.org.uk/emc/product/9693/smpc | access-date=1 October 2020}}</ref>|legal_US=Rx-only|legal_US_comment=<ref name="Pifeltro FDA label" />|legal_EU=Rx-only|legal_EU_comment=<ref>{{웹 인용| title=Pifeltro EPAR | website=[[European Medicines Agency]] (EMA) | url=https://www.ema.europa.eu/en/medicines/human/EPAR/pifeltro | access-date=1 October 2020}}</ref>|legal_status=<!-- Pharmacokinetic data -->|bioavailability=|StdInChIKey=ZIAOVIPSKUPPQW-UHFFFAOYSA-N}}
'''피펠트로(Pifeltro)'''라는 상표명으로 판매되는 '''도라비린(Doravirine)'''은 [[:en:Merck_&_Co.|Merck & Co.]]에서 개발한 [[후천면역결핍증후군|HIV/AIDS]] 치료용 비핵성 [[역전사효소 억제제]]이다.

도라비린(Doravirine)은 2018년 8월 미국에서 의료용으로 승인되었다.<ref>{{웹 인용|url=https://www.accessdata.fda.gov/drugsatfda_docs/nda/2018/210806Orig1s000,210807Orig1s000TOC.cfm|title=Drug Approval Package: Pifeltro (doravirine)|date=9 October 2018|website=U.S. [[Food and Drug Administration]] (FDA)|access-date=22 September 2020}}</ref>

== 각주 ==
{{각주}}

== 외부 링크 ==
* {{웹 인용|url=https://druginfo.nlm.nih.gov/drugportal/name/doravirine|title=Doravirine|work=Drug Information Portal|publisher=U.S. National Library of Medicine}}

{{항레트로바이러스제}}

[[분류:나이트릴]]
[[분류:질소 헤테로고리 화합물]]
[[분류:클로로아렌]]
[[분류:페놀 에터]]