{{위키데이터 속성 추적}}
{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 477174254
| ImageFile = Thebaine skeletal.svg
| ImageSize = 190
| ImageName = Skeletal formula
| ImageFile2 = Thebaine molecule ball.png
| ImageSize2 = 210
| ImageName2 = Ball-and-stick model
| IUPACName = 3,6-Dimethoxy-17-methyl-6,7,8,14-tetradehydro-4,5α-epoxymorphinan
| PIN = (4''R'',7a''R'',12b''S'')-7,9-Dimethoxy-3-methyl-2,3,4,7a-tetrahydro-1''H''-4,12-methano[1]benzofuro[3,2-''e'']isoquinoline
| OtherNames = Paramorphine
|Section1={{Chembox Identifiers
| Abbreviations = 
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 2P9MKG8GX7
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 403893
| InChI = 1S/C19H21NO3/c1-20-9-8-19-12-5-7-15(22-3)18(19)23-17-14(21-2)6-4-11(16(17)19)10-13(12)20/h4-7,13,18H,8-10H2,1-3H3/t13-,18+,19+/m1/s1
| InChIKey = FQXXSQDCDRQNQE-VMDGZTHMBG
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C19H21NO3/c1-20-9-8-19-12-5-7-15(22-3)18(19)23-17-14(21-2)6-4-11(16(17)19)10-13(12)20/h4-7,13,18H,8-10H2,1-3H3/t13-,18+,19+/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = FQXXSQDCDRQNQE-VMDGZTHMSA-N
| InChIKey1 = FQXXSQDCDRQNQE-VMDGZTHMSA-N
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 115-37-7
| ChemSpiderID = 4481822
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID1_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID1 = 4479543
| EINECS = 
| PubChem = 5324289
| SMILES = COC1=CC=C2[C@@H](C3)N(C)CC[C@@]24C5=C3C=CC(OC)=C5O[C@@H]14
| RTECS =
| MeSHName = Thebaine
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 9519
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = C06173
}}
|Section2={{Chembox Properties
| Formula =
| C=19 | H=21 | N=1 | O=3
| MolarMass = 311.37 g/mol
| Appearance =
| Density = 
| MeltingPt = 
| MeltingPt_notes =
| BoilingPt = 
| BoilingPt_notes = 
| Solubility = 
| SolubleOther = 
| Solvent = 
| pKa = 
| pKb = }}
|Section3={{Chembox Pharmacology
| ProteinBound = 
| Bioavail = 
| Metabolism = ''O''-demethylation<ref name="mikus1991">{{저널 인용|author1=Mikus, G. |author2=Somogyi, A. A. |author3=Bochner, F. |author4=Eichelbaum, M. | title = Thebaine O-demethylation to oripavine: Genetic differences between two rat strains | journal = Xenobiotica | year = 1991 | volume = 21 | issue = 11 | pages = 1501–9 | pmid = 1763524 | doi=10.3109/00498259109044400}}</ref>
| HalfLife = 
| Excretion = 
| Pregnancy_category = 
| Pregnancy_AU = 
| Legal_US = Schedule II
| Legal_UK = Class A
| Legal_AU = S8
| Legal_CA = Schedule I
| Legal_status = 
| AdminRoutes = 
| Licence_EU = 
| Licence_US =
| Dependence_liability = Low<ref name="who1980">{{저널 인용| author = WHO Advisory Group | title = The dependence potential of thebaine | journal = Bulletin on Narcotics | year = 1980 | volume = 32 | issue = 1 | pages = 45–54 | pmid = 6778542 | url = https://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1980-01-01_1_page006.html | url-status = live | archive-url = https://web.archive.org/web/20140512225626/https://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1980-01-01_1_page006.html | archive-date = 2014-05-12 }}</ref>}}
}}
'''테바인'''(Thebaine)은 [[아편제]] [[알칼로이드]]이다. 이 이름은 [[상이집트]]의 고대도시 [[테베 (이집트)|테베]]([[그리스어]] Θῆβαι)에서 기원한다. [[아편]]의 사소한 성분인 테바인은 화학적으로 [[모르핀]]과 [[코데인]]과 유사하지만 우울증 효과를 주기보다는 자극적이다. 많은 양을 복용하면 [[스트리크닌]] 중독과 비슷한 경련을 일으킨다.

== 합성 ==
=== 연구 ===
테바인은 [[유전자 변형 생물|GMO]] [[대장균]]에 의해 생성됨이 밝혀졌다.<ref>{{웹 인용|title=Genetically modified E. coli pump out morphine precursor: Bacteria yield 300 times more opiates than yeast |url=https://www.sciencedaily.com/releases/2016/02/160225101103.htm |website=ScienceDaily |language=en}}</ref>

== 각주 ==
{{각주}}

{{전거 통제}}

[[분류:에터]]
[[분류:사이클로헥사다이엔]]
[[분류:글라이신 수용체 대항제]]
[[분류:아편제]]
[[분류:경련 유발제]]
[[분류:4,5-에폭시모르피난]]