{{위키데이터 속성 추적}}
{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 460042943
| image = Clofazimine.svg
| alt = Structural formula of clofazimine
| width = 180
| image2 = Clofazimine 3D spacefill.png
| alt2 = Space-filling model of the clofazimine molecule
| width2 = 200

<!-- Clinical data -->
| pronounce         = 
| tradename = Lamprene
| Drugs.com = {{drugs.com|monograph|clofazimine}}
| MedlinePlus = a682128
| licence_CA        = <!-- Health Canada may use generic or brand name (generic name preferred) -->
| licence_EU        = <!-- EMA uses INN (or special INN_EMA) -->
| DailyMedID        = <!-- DailyMed may use generic or brand name (generic name preferred) -->
| licence_US        = <!-- FDA may use generic or brand name (generic name preferred) -->
| pregnancy_AU      = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_AU_comment = 
| pregnancy_US      = <!-- A / B / C / D / X / N -->
| pregnancy_US_comment = 
| pregnancy_category= 
| dependency_liability = 
| addiction_liability = 
| routes_of_administration = By mouth
| class             = 
| ATC_prefix = J04
| ATC_suffix = BA01
| ATC_supplemental =

<!-- Legal status -->
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled -->
| legal_AU_comment = 
| legal_BR =  <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F -->
| legal_BR_comment = 
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_CA_comment = 
| legal_DE = <!-- Anlage I, II, III or Unscheduled -->
| legal_DE_comment = 
| legal_NZ = <!-- Class A, B, C -->
| legal_NZ_comment = 
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C -->
| legal_UK_comment = 
| legal_US = Rx-only
| legal_US_comment = 
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV -->
| legal_UN_comment = 
| legal_status      = <!-- For countries not listed above -->

<!-- Pharmacokinetic data -->
| bioavailability =  
| protein_bound =  
| metabolism =  
| elimination_half-life = 70 days

<!-- Identifiers -->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 2030-63-9
| PubChem = 2794
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB00845
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID      = 21159573
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = D959AE5USF
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00278
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1292
| synonyms = <small>''N'',5-''bis''(4-chlorophenyl)-3-(1-methylethylimino)-5''H''-phenazin-2-amine </small>

<!-- Chemical and physical data -->
| IUPAC_name = ''N'',5-''bis''(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine
| C=27 | H=22 | Cl=2 | N=4
| molecular_weight = 473.396
| smiles            = CC(C)/N=c/1\cc-2n(c3ccccc3nc2cc1Nc4ccc(cc4)Cl)c5ccc(cc5)Cl
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI          = 1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey       = WDQPAMHFFCXSNU-UHFFFAOYSA-N
| melting_point = 210
| melting_high = 212
}}

'''클로파지민'''(Clofazimine, 브랜드명: Lamprene)은 [[나병]]을 치료하기 위해 [[리팜피신]]과 [[댑손]]과 함께 사용되는 약물이다.<ref name="AHFS2016">{{웹 인용|title=Clofazimine|url=https://www.drugs.com/monograph/clofazimine.html|publisher=The American Society of Health-System Pharmacists|access-date=8 December 2016|url-status=live|archive-url=https://web.archive.org/web/20161220231051/https://www.drugs.com/monograph/clofazimine.html|archive-date=20 December 2016}}</ref> 특히 다세균성(MB) 나병과 [[나성결절홍반]]에 사용된다.<ref name=WHO2008>{{서적 인용| title = WHO Model Formulary 2008 | year = 2009 | isbn = 9789241547659 | vauthors = ((World Health Organization)) | veditors = Stuart MC, Kouimtzi M, Hill SR | hdl = 10665/44053 | author-link = World Health Organization | publisher = World Health Organization | hdl-access=free | page=132 }}</ref> 미국에서 클로파지민은 [[희귀의약품]]으로 간주되어 약국에서 구할 수 없다.

== 각주 ==
{{각주}}

== 외부 링크 ==
* {{웹 인용| title=Lamprene (clofazimine) capsules, for oral use Initial U.S. Approval: 1986 | website=DailyMed | date=31 January 2019 | url=https://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=382477 | access-date=14 June 2020}}</ref>

{{토막글|의학}}

[[분류:희귀약]]
[[분류:세계 보건 기구 필수 의약품]]
[[분류:클로로아렌]]
[[분류:나병 치료제]]