{{위키데이터 속성 추적}}
{{Drugbox
| Watchedfields = changed
| verifiedrevid = 443251358
| IUPAC_name = 4,5α-epoxy-3-methoxy-17-methylmorphinan-6-one
| image = Hydrocodone skeletal.svg
| width = 200px
| image2 = Hydrocodone-Spartan-PM3-3D-balls.png
| width2 = 225px

<!--Clinical data-->
| tradename = Vicodin, Norco, many others
| Drugs.com = {{drugs.com|CONS|hydrocodone}}
| MedlinePlus = a601006
| pregnancy_US = C
| legal_AU = Schedule 8
| legal_CA = Schedule I
| legal_DE = Anlage III
| legal_UK = Class A
| legal_US = Schedule II
| dependency_liability = Very high
| routes_of_administration = Clinical: [[oral administration|oral]]<ref name="ElliottSmith2016">{{서적 인용|author1=Jennifer A. Elliott|author2=Howard S. Smith|title=Handbook of Acute Pain Management|url=https://books.google.com/books?id=Em7OBQAAQBAJ&pg=PA79|date=19 April 2016|publisher=CRC Press|isbn=978-1-4665-9635-1|pages=79–}}</ref><br />Others: [[intranasal administration|intranasal]], [[rectal administration|rectal]]

<!--Pharmacokinetic data-->
| bioavailability = [[Oral administration|Oral]]: 70%<ref name="FiresteinBudd2016">{{서적 인용|author1=Gary S. Firestein|author2=Ralph Budd|author3=Sherine E. Gabriel|author4=Iain B. McInnes |author5=James R. O'Dell|title=Kelley and Firestein's Textbook of Rheumatology|url=https://books.google.com/books?id=kBZ6DAAAQBAJ&pg=PA1081|date=21 June 2016|publisher=Elsevier Health Sciences|isbn=978-0-323-41494-4|pages=1081–}}</ref>
| protein_bound = Low<ref name="FiresteinBudd2016" /><ref name="ChabnerLongo2010">{{서적 인용|author1=Bruce A. Chabner|author2=Dan L. Longo|title=Cancer Chemotherapy and Biotherapy: Principles and Practice|url=https://books.google.com/books?id=WL4arNFsQa8C&pg=PA700|date=8 November 2010|publisher=Lippincott Williams & Wilkins|isbn=978-1-60547-431-1|pages=700–}}</ref>
| metabolism = [[Liver]]: [[CYP3A4]] (major), [[CYP2D6]] (minor)<ref name="Zhou2016">{{서적 인용|author=Shufeng Zhou|title=Cytochrome P450 2D6: Structure, Function, Regulation and Polymorphism|url=https://books.google.com/books?id=UJqmCwAAQBAJ&pg=PA164|date=6 April 2016|publisher=CRC Press|isbn=978-1-4665-9788-4|pages=164–}}</ref>
| metabolites = • [[Norhydrocodone]]<ref name="Zhou2016" /><br />• [[Hydromorphone]]<ref name="Zhou2016" /><br />• Others<ref name="Zhou2016" />
| onset = 10–20 minutes<ref name="ElliottSmith2016" />
| elimination_half-life = Average: 3.8 hours<ref name="DavisGlare2005">{{서적 인용|author1=Mellar P. Davis|author2=Paul Glare|author3=Janet Hardy|title=Opioids in Cancer Pain|url=https://books.google.com/books?id=BK0WduGnx2kC&pg=PA59|year=2005|publisher=Oxford University Press|isbn=978-0-19-852943-9|pages=59–68}}</ref><br />Range: 3.3–4.4 hours<ref name="ElliottSmith2016" />
| duration_of_action = 4–8 hours<ref name="ElliottSmith2016" />
| excretion = [[Urine]]<ref name="Bluth2016">{{서적 인용|author=Martin H. Bluth|title=Toxicology and Drug Testing, An Issue of Clinics in Laboratory Medicine, E-Book|url=https://books.google.com/books?id=NAKRDQAAQBAJ&pg=PT85|date=16 November 2016|publisher=Elsevier Health Sciences|isbn=978-0-323-47795-6|pages=85–}}</ref><ref name="Smith2013">{{서적 인용|author=Howard S. Smith|title=Opioid Therapy in the 21st Century|url=https://books.google.com/books?id=MBxWFigSEE8C&pg=PT68|date=21 February 2013|publisher=OUP USA|isbn=978-0-19-984497-5|pages=68–}}</ref>

<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|CAS}}
| CAS_number = 125-29-1
| ATC_prefix = R05
| ATC_suffix = DA03
| PubChem = 5284569
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 5779
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1457
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4447623
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB00956
| IUPHAR_ligand = 7081
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D08045
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 6YKS4Y3WQ7
| synonyms = Dihydrocodeinone

<!--Chemical data-->
| C=18 | H=21 | N=1 | O=3
| molecular_weight = 299.368 g/mol
| SMILES = O=C4[C@@H]5Oc1c2c(ccc1OC)C[C@H]3N(CC[C@]25[C@H]3CC4)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = LLPOLZWFYMWNKH-CMKMFDCUSA-N
}}
'''하이드로콘, 히드로코돈'''(영문:hydrocodone) 혹은 '''하이드로콘데이논, 히드로콘데이논'''(영문:dihydrocodeinone)이라고 한다. 마약성 진통제로 [[아편]] 추출물이다. 보통 [[아세트아미노펜]]과 [[하이드로콘]]과 합성된 제품으로 나오며 의사의 처방전을 받으면 구입할 수 있다.

== 각주 ==
{{각주}}

== 외부 링크 ==
* [http://druginfo.nlm.nih.gov/drugportal/dpdirect.jsp?name=Hydrocodone Hydrocodone] at [[United States National Library of Medicine|U.S. National Library of Medicine]]: Drug Information Portal

{{토막글|의학}}

[[분류:도취제]]
[[분류:독일의 발명품]]
[[분류:케톤]]
[[분류:뮤 오피오이드 수용체 작용제]]
[[분류:페놀 에터]]
[[분류:반합성 오피오이드]]
[[분류:4,5-에폭시모르피난]]