{{위키데이터 속성 추적}}
{{Drugbox
| Watchedfields = changed
| verifiedrevid = 477169864
| IUPAC_name = 2-(3,4,5-Trimethoxyphenyl)ethanamine
| image = Mescaline Structural Formula.svg
| image2 = Mescaline-3D-xray-ballstick.png
<!--Clinical data-->
| Drugs.com = {{drugs.com|parent|mescaline}}
| pregnancy_US = C
| legal_AU = Schedule 9
| legal_CA = Schedule III
| legal_UK = Class A
| legal_US = Schedule I
| legal_DE = Anlage I
| routes_of_administration = [[:en:wikt:oral|Oral]], intravenous
<!--Pharmacokinetic data-->
| elimination_half-life = 6 hours
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|CAS}}
| CAS_number = 54-04-6
| ATC_prefix = none
| PubChem = 4076
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 3934
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = RHO99102VC
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = C06546
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 28346
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 26687
<!--Chemical data-->
| C=11 | H=17 | N=1 | O=3
| smiles = O(c1cc(cc(OC)c1OC)CCN)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = RHCSKNNOAZULRK-UHFFFAOYSA-N
| synonyms = 3,4,5-Trimethoxyphenethylamine
| melting_point = 35
| melting_high = 36
| boiling_point = 180
| boiling_notes = at 12 mmHg
}}
'''메스칼린'''({{lang|en|mescaline}}, 3,4,5-trimethoxyphenethylamine)은 [[천연물]]에서 추출한 페닐에틸아민계 [[환각성 약물|환각성]] [[알칼로이드]]이며, [[리세르그산 디에틸아미드|LSD]]와 [[실로시빈]]에 맞먹는 [[환각제|환각]] 효과로 알려져 있다.<ref>{{저널 인용|제목=Finding medical value in mescaline|저널=Nature|성=Bender|이름=Eric|url=https://www.nature.com/articles/d41586-022-02873-8|날짜=2022-09-28|권=609|호=7929|쪽=S90–S91|언어=en|doi=10.1038/d41586-022-02873-8}}</ref>

[[페요테]] 선인장(''Lophophora williamsii''),<ref name=Bib>{{서적 인용|title=Drug Identification Bible |year=2007 |publisher=Amera-Chem, Inc. |location=Grand Junction, CO |isbn=978-0-9635626-9-2 }}</ref> [[성게선인장]](''Echinopsis pachanoi''),<ref>{{저널 인용|author1=Crosby, D.M. |author2=McLaughlin, J.L. |title=Cactus Alkaloids. XIX Crystallization of Mescaline HCl and 3-Methoxytyramine HCl from Trichocereus panchanoi|journal=Lloydia and the Journal of Natural Products|date=December 1973|volume=36|issue=4|pages=416–418|pmid=4773270|url=http://catbull.com/alamut/Bibliothek/1973_d.m._crosby_8158_1.pdf|accessdate=13 December 2013}}</ref> [[페루비안 토치]](''Echinopsis peruviana''),<ref name=OgunMcCoTrouDale10>{{저널 인용|last1=Ogunbodede |first1=Olabode |last2=McCombs |first2=Douglas |last3=Trout |first3=Keeper |last4=Daley |first4=Paul |last5=Terry |first5=Martin |date=2010 |title=New mescaline concentrations from 14 taxa/cultivars of ''Echinopsis'' spp. (Cactaceae) ("San Pedro") and their relevance to shamanic practice |journal=Journal of Ethnopharmacology |volume=131 |issue=2 |pages=356–362 |doi=10.1016/j.jep.2010.07.021 |pmid=20637277}}</ref> 등의 [[선인장]] 식물에서 자연적으로 발생된다. 적은 양이지만 [[아카시아 나무]](acacia berlandieri)를 포함한 [[콩과]]의 특정 부류에서도 발견된다.<ref name="chem">{{저널 인용|title=Chemistry of Acacia's from South Texas |publisher=Texas A&M Agricultural Research & Extension Center at Uvalde |url=http://uvalde.tamu.edu/pdf/chemtdaf.pdf |archiveurl=https://web.archive.org/web/20110515034950/http://uvalde.tamu.edu/pdf/chemtdaf.pdf |archivedate=15 May 2011 |author1=Forbes, T.D.A. |author2=Clement, B.A. |url-status=dead |df= }}</ref> 그러나 아카시아종에 관련된 주장은 도전을 받고 있으며 추가 분석을 통해 해당 주장을 뒷받침하지는 않고 있다.

== 생합성 ==
[[파일:Mescaline biosynthetic pathways.svg|섬네일|왼쪽|400px|메스칼린의 생합성]]{{clear left}}

== 적법성 ==
=== 미국 ===
미국에서 메스칼린은 [[규제약물법]]에 의해 스케줄 I 환각제로 분류되면서 1970년에 불법화되었다.<ref>{{웹 인용|url=http://www.usdoj.gov/dea/pubs/scheduling.html |title=Drug Scheduling |accessdate=2 November 2007 |author=United States Department of Justice |authorlink=United States Department of Justice |archive-url=https://web.archive.org/web/20081020210309/http://www.usdoj.gov/dea/pubs/scheduling.html |archive-date=20 October 2008 |url-status=dead |df=dmy-all }}</ref> 이 약물은 1971년 [[향정신성물질에 관한 협약]]에 의해 국제적으로 금지되었다.<ref>{{웹 인용|url=http://www.incb.org/pdf/e/list/green.pdf |title=List of psychotropic substances under international control |publisher=[[:en:International Narcotics Control Board]] |accessdate=27 January 2008 |url-status=dead |archiveurl=https://web.archive.org/web/20051205125434/http://www.incb.org/pdf/e/list/green.pdf |archivedate=5 December 2005 |df= }}</ref>

=== 영국 ===
영국에서 정제된 가루 형태의 메스칼린은 A급 약물이다. 그러나 건조한 선인장을 도입 및 합법적인 판매가 가능하다.<ref>{{웹 인용|url=http://www.erowid.org/plants/cacti/cacti_law2.shtml |title=2007 U.K. Trichocereus Cacti Legal Case Regina v. Saul Sette |publisher=Erowid.org |date=June 2007 |accessdate=6 April 2012 }}</ref>

== 같이 보기 ==
* [[향정신성의약품]]

== 각주 ==
{{각주}}

== 외부 링크 ==
{{위키공용|Mescaline}}
* [https://web.archive.org/web/20090326163130/http://drugabuse.gov/Infofacts/hallucinogens.html National Institutes of Health – National Institute on Drug Abuse Hallucinogen InfoFacts]
* [http://www.erowid.org/chemicals/mescaline/mescaline.shtml Mescaline] at [[:en:Erowid]]
* [http://www.erowid.org/library/books_online/pihkal/pihkal096.shtml PiHKAL entry]
* [http://pihkal.info/read.php?domain=pk&id=96 Mescaline entry in PiHKAL • info]
* {{유튜브|Hd4rgyZzseY|Film of Christopher Mayhew's mescaline experiment}}
* [https://web.archive.org/web/20060215094333/http://diseyes.lycaeum.org/cact/final.htm Mescaline: The Chemistry and Pharmacology of its Analogs], an essay by [[:en:Alexander Shulgin]]
* [http://www.houstonpress.com/2008-02-14/news/mescaline-on-the-mexican-border/ Mescaline on the Mexican Border] {{웨이백|url=http://www.houstonpress.com/2008-02-14/news/mescaline-on-the-mexican-border/ |date=20150421230757 }}

{{전거 통제}}

[[분류:천연물]]
[[분류:영춘환선인장아과]]
[[분류:세로토닌 수용체 작용제]]
[[분류:페놀 에터]]
[[분류:의식용 환각제]]
[[분류:펜에틸아민 알칼로이드]]