{{위키데이터 속성 추적}}
'''하이드록시카복실산 수용체 2'''({{llang|en|hydroxycarboxylic acid receptor 2}}, '''HCA<sub>2</sub>''')는 사람에서 HCAR2 [[유전자]]에 의해 암호화되는 [[단백질]]이다.<ref name="pmid12044878">{{저널 인용| vauthors = Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S | title = Identification of G protein-coupled receptor genes from the human genome sequence | journal = FEBS Letters | volume = 520 | issue = 1–3 | pages = 97–101 | date = June 2002 | pmid = 12044878 | doi = 10.1016/S0014-5793(02)02775-8 | s2cid = 7116392 | doi-access = free }}</ref><ref name="entrez">{{웹 인용| title = Entrez Gene: GPR109A G protein-coupled receptor 109A| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=338442}}</ref><ref name="pmid12522134">{{저널 인용| vauthors = Wise A, Foord SM, Fraser NJ, Barnes AA, Elshourbagy N, Eilert M, Ignar DM, Murdock PR, Steplewski K, Green A, Brown AJ, Dowell SJ, Szekeres PG, Hassall DG, Marshall FH, Wilson S, Pike NB | title = Molecular identification of high and low affinity receptors for nicotinic acid | journal = The Journal of Biological Chemistry | volume = 278 | issue = 11 | pages = 9869–74 | date = March 2003 | pmid = 12522134 | doi = 10.1074/jbc.M210695200 | doi-access = free }}</ref><ref name="pmid12646212">{{저널 인용| vauthors = Soga T, Kamohara M, Takasaki J, Matsumoto S, Saito T, Ohishi T, Hiyama H, Matsuo A, Matsushime H, Furuichi K | title = Molecular identification of nicotinic acid receptor | journal = Biochemical and Biophysical Research Communications | volume = 303 | issue = 1 | pages = 364–9 | date = March 2003 | pmid = 12646212 | doi = 10.1016/S0006-291X(03)00342-5 }}</ref> '''니아신 수용체 1'''({{llang|en|niacin receptor 1}}, '''NIACR1'''), '''G 단백질 연결 수용체 109A'''({{llang|en|G protein-coupled receptor 109A}}, '''GPR109A''')라고도 한다.<ref>{{저널 인용|title=International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B)|journal=Pharmacological Reviews|date=June 2011|volume=63|issue=2|pages=269–90|doi=10.1124/pr.110.003301|pmid=21454438|vauthors=Offermanns S, Colletti SL, Lovenberg TW, Semple G, Wise A, IJzerman AP|doi-access=free}}</ref> 하이드록시카복실산 수용체 2()는 다른 [[하이드록시카복실산 수용체]]인 [[하이드록시카복실산 수용체 1]](HCA<sub>1</sub>) 및 [[하이드록시카복실산 수용체 3]](HCA<sub>3</sub>)과 마찬가지로 [[Gi 단백질 α 소단위체|G<sub>i/o</sub>-연결]] [[G 단백질 연결 수용체]](GPCR)이다.<ref name="IUPHAR's comprehensive 2011 review on HCARs" /><ref name="IUPHAR-DB HCAR family page" /> 하이드록시카복실산 수용체 2(HCA<sub>2</sub>)의 주요 [[내인성]] [[작용제]]는 [[β-하이드록시뷰티르산]] 및 [[뷰티르산]](및 이들의 [[짝염기]]인 [[β-하이드록시뷰티르산염]] 및 [[뷰티르산염]])이다.<ref name="IUPHAR's comprehensive 2011 review on HCARs">{{저널 인용| vauthors = Offermanns S, Colletti SL, Lovenberg TW, Semple G, Wise A, IJzerman AP | title = International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B) | journal = Pharmacological Reviews | volume = 63 | issue = 2 | pages = 269–90 | date = June 2011 | pmid = 21454438 | doi = 10.1124/pr.110.003301 | doi-access = free }}</ref><ref name="IUPHAR-DB HCAR family page">{{웹 인용|author1=S Offermanns, SL Colletti, AP IJzerman, TW Lovenberg, G Semple, A Wise, MG Waters |title=Hydroxycarboxylic acid receptors |url=http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=48 |website=IUPHAR/BPS Guide to Pharmacology |publisher=International Union of Basic and Clinical Pharmacology |access-date=13 July 2018}}</ref> 하이드록시카복실산 수용체 2(HCA<sub>2</sub>)는 또한 [[니아신]](일명 [[니코틴산]])에 대한 [[리간드 (생화학)|고친화성]] [[생체분자 표적]]이다.<ref name="pmid12522134"/><ref name="pmid12646212"/>

== 같이 보기 ==
* [[하이드록시카복실산]]
* [[하이드록시카복실산 수용체]]
* [[하이드록시카복실산 수용체 1]]
* [[하이드록시카복실산 수용체 3]]

== 각주 ==
{{각주}}

[[분류:인간 12번 염색체상 유전자]]
[[분류:G 단백질 연결 수용체]]