{{위키데이터 속성 추적}}
{{Drugbox
| Watchedfields = changed
| verifiedrevid = 443306800
| IUPAC_name = (8''S'',11''R'',13''S'',14''S'',17''S'')-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[''a'']phenanthren-3-one
| image = Mifepristone structure.svg
| width = 200px
| image2 = Mifepristona3D.png
| width2 = 200px

<!--Clinical data-->
| tradename = Mifegyne, Mifeprex, others
| Drugs.com = {{drugs.com|monograph|mifepristone}}
| MedlinePlus = a600042
| pregnancy_US = X
| pregnancy_category = [[Abortifacient|Used for terminating pregnancy]]
| legal_US = Rx-only
| legal_status = Rx-only
| routes_of_administration = [[Oral administration|By mouth]]
| class = [[Antiprogestogen]]; [[Antiglucocorticoid]]

<!--Pharmacokinetic data-->
| bioavailability = 69%
| protein_bound = 98%
| metabolism = [[Liver]]
| elimination_half-life = 
| excretion = [[Feces]]: 83%<br />[[Urine]]: 9%

<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 84371-65-3
| ATC_prefix = G03
| ATC_suffix = XB01
| PubChem = 55245
| IUPHAR_ligand = 2805
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB00834
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 49889
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 320T6RNW1F
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00585
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 50692
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 157
| synonyms = RU-486; RU-38486; ZK-98296; 11β-[''p''-(Dimethylamino)phenyl]-17α-(1-propynyl)estra-4,9-dien-17β-ol-3-one

<!--Chemical data-->
| C=29 | H=35 | N=1 | O=2
| molecular_weight = 429.604 g/mol
| SMILES = O=C5\C=C4/C(=C3/[C@@H](c1ccc(N(C)C)cc1)C[C@]2([C@@H](CC[C@]2(C#CC)O)[C@@H]3CC4)C)CC5
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = VKHAHZOOUSRJNA-GCNJZUOMSA-N

<!--Physical data-->
| density = 1.189
| melting_point = 194
| boiling_point = 629
}}
'''미페프리스톤'''(Mifepristone, RU-486)은 일반적으로 [[미소프로스톨]]과 함께 [[임신]] 중에 [[낙태]]를 유도하고, 조기 [[유산 (의학)|유산]]을 위해 사용되는 약물이다.<ref name="AHFS2015">{{웹 인용|title=Mifepristone |url=https://www.drugs.com/monograph/mifepristone.html |url-status=live |archive-url=https://web.archive.org/web/20151222083002/http://www.drugs.com/monograph/mifepristone.html |archive-date=22 December 2015 |access-date=25 February 2023 |publisher=[[American Society of Health System Pharmacists]] |via=[[Drugs.com]]}}</ref> 임신 첫 63일 (9주) 동안 97% 효과적이다.<ref name="Chen2015">{{저널 인용|vauthors=Chen MJ, Creinin MD |date=July 2015 |title=Mifepristone With Buccal Misoprostol for Medical Abortion: A Systematic Review |url=http://www.escholarship.org/uc/item/2pw521h5 |url-status=live |journal=[[Obstetrics & Gynecology (journal)|Obstetrics and Gynecology]] |volume=126 |issue=1 |pages=12–21 |doi=10.1097/AOG.0000000000000897 |pmid=26241251 |s2cid=20800109 |archive-url=https://web.archive.org/web/20200726105924/https://escholarship.org/uc/item/2pw521h5 |archive-date=26 July 2020 |access-date=27 July 2019 |via=[[eScholarship]]}}</ref> 임신 중기에도 효과적이다.<ref name="Rex2012">{{서적 인용|url=https://books.google.com/books?id=mavb4v8w8bsC&pg=PA236 |title=Women and Health |date=2012 |publisher=Academic Press |isbn=978-0-12-384979-3 |veditors=Goldman MB, [[Rebecca J. Troisi|Troisi R]], Rexrode KM |edition=2nd |location=Oxford |page=236 |access-date=5 September 2017 |archive-url=https://web.archive.org/web/20170908184336/https://books.google.com/books?id=mavb4v8w8bsC&pg=PA236 |archive-date=8 September 2017 |url-status=live |via=Google Books}}</ref><ref>{{저널 인용| vauthors = Wildschut H, Both MI, Medema S, Thomee E, Wildhagen MF, Kapp N | title = Medical methods for mid-trimester termination of pregnancy | journal = The Cochrane Database of Systematic Reviews | issue = 1 | pages = CD005216 | date = January 2011 | volume = 2011 | pmid = 21249669 | doi = 10.1002/14651858.CD005216.pub2 | pmc = 8557267 }}</ref> 경구투여 한다.<ref name=AHFS2015/>

== 각주 ==
<references />

== 외부 링크 ==
* [https://gynuity.org/assets/resources/mapmifelist_en.pdf 연도별 미페프리스톤 승인 국가 목록] {{웨이백|url=https://gynuity.org/assets/resources/mapmifelist_en.pdf |date=20230529053718 }}

{{전거 통제}}
{{토막글|화학}}

[[분류:아닐린]]
[[분류:프랑스의 발명품]]
[[분류:세계 보건 기구 필수 의약품]]
[[분류:에스트란]]
[[분류:세로토닌 재흡수 억제제]]
[[분류:프레그난 X 수용체 작용제]]
[[분류:CYP3A4 억제제]]
[[분류:스테로이드성 항안드로겐]]
[[분류:CYP17A1 억제제]]
[[분류:낙태약]]