{{위키데이터 속성 추적}}
{{과학자 정보
|이름         = 마이클 스튜어트 브라운 {{노벨상 딱지}}
|원어이름     = Michael Stuart Brown
|그림         = Mike Brown 2003.jpg
|그림 크기    = 200px
|그림 설명    = 2003년 촬영
|태어난 날    = {{출생일과 나이|1941|4|13}}
|태어난 곳    = [[미국]] [[뉴욕주]] [[브루클린]]
|죽은 날      = 
|죽은 곳      = 
|거주지       = 
|국적         = [[미국]]
|분야         = [[유전학]]
|소속         = 
|출신 대학    = [[펜실베이니아 대학교]]
|지도교수     = 
|지도학생     = 
|주요 업적    = [[콜레스테롤]] 연구
|수상         = 하인리히 빌란트상(1974년)<br />리처드 런즈베리상(1979년)<br />[[가드너 국제상]](1981년)<br />[[루이자 그로스 호르위츠상]](1984년)<br />윌리엄 앨런상(1985년)<br />[[앨버트 래스커 기초 의학 연구상]](1985년)<br />[[노벨 생리학·의학상]](1985년)<br />[[미국 국가 과학상]](1988년)<br />[[왕립학회 회원|ForMemRS]](1991년)<ref name=formemrs/><br />[[올버니 의료센터 상]](2003년)
}}
'''마이클 스튜어트 브라운'''({{llang|en|Michael Stuart Brown}}, [[왕립학회 회원|ForMemRS]]<ref name=formemrs>{{웹 인용|archiveurl=https://web.archive.org/web/20151106214111/https://royalsociety.org/people/michael-brown-11147/|archivedate=2015-11-06|url=https://royalsociety.org/people/michael-brown-11147/|title=Professor Michael Brown ForMemRS|publisher=[[왕립학회|Royal Society]]|location=London}}</ref>, [[1941년]] [[4월 13일]] ~ )은 [[미국]]의 [[유전학]]자이다. 1985년에 [[콜레스테롤]] 신진 [[물질대사|대사]] 과정에 관한 연구로 [[조지프 L. 골드스타인]]과 함께 [[노벨 생리학·의학상]]을 수상했다.<ref>{{웹 인용| title=Biography: Michael S. Brown | url=http://www.nndb.com/people/174/000123802 | work=The Notable Names Database | publisher=Soylent Communications| year=2008 | accessdate=2008-06-15}}</ref><ref>{{웹 인용|url=http://www.nobelprizeii.org/nobel-laureate/michael-brown/ |title=Michael Brown - Nobel Prize Inspiration Initiative |publisher=Nobelprizeii.org |date= |accessdate=2015-11-06}}</ref><ref name="nobelprize1985">{{웹 인용|url=https://www.nobelprize.org/nobel_prizes/medicine/laureates/1985/brown-bio.html |title=Michael S. Brown - Biographical |publisher=Nobelprize.org |date=1941-04-13 |accessdate=2015-11-06}}</ref><ref>{{웹 인용|url=https://www.nobelprize.org/nobel_prizes/medicine/laureates/1985/brown-lecture.html |title=Michael S. Brown - Nobel Lecture: A Receptor-Mediated Pathway for Cholesterol Homeostasis |publisher=Nobelprize.org |date=1985-12-08 |accessdate=2015-11-06}}</ref>

== 수상 경력 ==
* 1974년 : 하인리히 빌란트상
* 1979년 : 리처드 런즈베리상
* 1981년 : [[가드너 국제상]]
* 1984년 : [[루이자 그로스 호르위츠상]]
* 1985년 : 윌리엄 앨런상
* 1985년 : [[앨버트 래스커 기초 의학 연구상]]
* 1985년 : 노벨 생리학·의학상
* 1988년 : [[미국 국가 과학상]]
* 2003년 : [[올버니 의료센터 상]]

== 회원 ==
* 1991년 : [[왕립학회]] 외국인 회원<ref name=formemrs/>

== 참고 문헌 ==
{{colbegin||colwidth=30em}}
* {{저널 인용|vauthors=Brown MS, Goldstein JL |title=Expression of the familial hypercholesterolemia gene in heterozygotes: mechanism for a dominant disorder in man |journal=Science |volume=185 |issue=4145 |pages=61–3 |date=Jul 1974 |pmid=4366052 |doi= 10.1126/science.185.4145.61|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=4366052}}
* {{저널 인용|vauthors=Brown MS, Goldstein JL |title=Regulation of the activity of the low density lipoprotein receptor in human fibroblasts |journal=Cell |volume=6 |issue=3 |pages=307–16 |date=Nov 1975 |pmid=212203 |doi= 10.1016/0092-8674(75)90182-8|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(75)90182-8}}
* {{저널 인용|vauthors=Goldstein JL, Basu SK, Brunschede GY, Brown MS |title=Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans |journal=Cell |volume=7 |issue=1 |pages=85–95 |date=Jan 1976 |pmid=181140 |doi= 10.1016/0092-8674(76)90258-0|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(76)90258-0}}
* {{저널 인용|vauthors=Brown MS, Goldstein JL |title=Receptor-mediated control of cholesterol metabolism |journal=Science |volume=191 |issue=4223 |pages=150–4 |date=Jan 1976|pmid=174194 |doi= 10.1126/science.174194|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=174194}}
* {{저널 인용|vauthors=Goldstein JL, Sobhani MK, Faust JR, Brown MS |title=Heterozygous familial hypercholesterolemia: failure of normal allele to compensate for mutant allele at a regulated genetic locus |journal=Cell |volume=9 |issue=2 |pages=195–203 |date=Oct 1976 |pmid=184960 |doi= 10.1016/0092-8674(76)90110-0|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(76)90110-0}}
* {{저널 인용|vauthors=Brown MS, Goldstein JL |title=Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein |journal=Cell |volume=9 |issue=4 PT 2 |pages=663–74 |date=Dec 1976 |pmid=189940 |doi= 10.1016/0092-8674(76)90130-6|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(76)90130-6}}
* {{저널 인용|vauthors=Anderson RG, Brown MS, Goldstein JL |title=Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts |journal=Cell |volume=10 |issue=3 |pages=351–64 |date=Mar 1977 |pmid=191195 |doi= 10.1016/0092-8674(77)90022-8|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(77)90022-8}}
* {{저널 인용|vauthors=Goldstein JL, Brown MS, Stone NJ |title=Genetics of the LDL receptor: evidence that the mutations affecting binding and internalization are allelic |journal=Cell |volume=12 |issue=3 |pages=629–41 |date=Nov 1977 |pmid=200368 |doi= 10.1016/0092-8674(77)90263-X|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(77)90263-X}}
* {{저널 인용|vauthors=Anderson RG, Goldstein JL, Brown MS |title=A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts |journal=Nature |volume=270 |issue=5639 |pages=695–9 |year=1977 |pmid=201867 |doi= 10.1038/270695a0|url=}}
* {{저널 인용|vauthors=Anderson RG, Vasile E, Mello RJ, Brown MS, Goldstein JL |title=Immunocytochemical visualization of coated pits and vesicles in human fibroblasts: relation to low density lipoprotein receptor distribution |journal=Cell |volume=15 |issue=3 |pages=919–33 |date=Nov 1978 |pmid=215316 |doi= 10.1016/0092-8674(78)90276-3|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(78)90276-3}}
* {{저널 인용|vauthors=Goldstein JL, Anderson RG, Brown MS |title=Coated pits, coated vesicles, and receptor-mediated endocytosis |journal=Nature |volume=279 |issue=5715 |pages=679–85 |date=Jun 1979 |pmid=221835 |doi= 10.1038/279679a0|url=}}
* {{저널 인용|vauthors=Mello RJ, Brown MS, Goldstein JL, Anderson RG |title=LDL receptors in coated vesicles isolated from bovine adrenal cortex: binding sites unmasked by detergent treatment |journal=Cell |volume=20 |issue=3 |pages=829–37 |date=Jul 1980 |pmid=6251975 |doi= 10.1016/0092-8674(80)90329-3|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(80)90329-3}}
* {{저널 인용|vauthors=Brown MS, Kovanen PT, Goldstein JL |title=Regulation of plasma cholesterol by lipoprotein receptors |journal=Science |volume=212 |issue=4495 |pages=628–35 |date=May 1981 |pmid=6261329 |doi= 10.1126/science.6261329|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=6261329}}
* {{저널 인용|vauthors=Basu SK, Goldstein JL, Anderson RG, Brown MS |title=Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts |journal=Cell |volume=24 |issue=2 |pages=493–502 |date=May 1981 |pmid=6263497 |doi= 10.1016/0092-8674(81)90340-8|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(81)90340-8}}
* {{저널 인용|vauthors=Tolleshaug H, Goldstein JL, Schneider WJ, Brown MS |title=Posttranslational processing of the LDL receptor and its genetic disruption in familial hypercholesterolemia |journal=Cell |volume=30 |issue=3 |pages=715–24 |date=Oct 1982 |pmid=6291781 |doi= 10.1016/0092-8674(82)90276-8|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(82)90276-8}}
* {{저널 인용|vauthors=Basu SK, Goldstein JL, Brown MS |title=Independent pathways for secretion of cholesterol and apolipoprotein E by macrophages |journal=Science |volume=219 |issue=4586 |pages=871–3 |date=Feb 1983 |pmid=6823554 |doi= 10.1126/science.6823554|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=6823554}}
* {{저널 인용|vauthors=Brown MS, Anderson RG, Goldstein JL |title=Recycling receptors: the round-trip itinerary of migrant membrane proteins |journal=Cell |volume=32 |issue=3 |pages=663–7 |date=Mar 1983 |pmid=6299572 |doi= 10.1016/0092-8674(83)90052-1|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(83)90052-1}}
* {{저널 인용|vauthors=Tolleshaug H, Hobgood KK, Brown MS, Goldstein JL |title=The LDL receptor locus in familial hypercholesterolemia: multiple mutations disrupt transport and processing of a membrane receptor |journal=Cell |volume=32 |issue=3 |pages=941–51 |date=Mar 1983 |pmid=6299582 |doi= 10.1016/0092-8674(83)90079-X|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(83)90079-X}}
* {{저널 인용|vauthors=Larkin JM, Brown MS, Goldstein JL, Anderson RG |title=Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts |journal=Cell |volume=33 |issue=1 |pages=273–85 |date=May 1983 |pmid=6147196 |doi= 10.1016/0092-8674(83)90356-2|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(83)90356-2}}
* {{저널 인용|vauthors=Orci L, Brown MS, Goldstein JL, Garcia-Segura LM, Anderson RG |title=Increase in membrane cholesterol: a possible trigger for degradation of HMG CoA reductase and crystalloid endoplasmic reticulum in UT-1 cells |journal=Cell |volume=36 |issue=4 |pages=835–45 |date=Apr 1984 |pmid=6705048 |doi= 10.1016/0092-8674(84)90033-3|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(84)90033-3}}
* {{저널 인용|author=Chin DJ |title=Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum |journal=Nature |volume=308 |issue=5960 |pages=613–7 |year=1984 |pmid=6546784 |doi= 10.1038/308613a0|url= |name-list-format=vanc|author2=Gil G |author3=Russell DW |display-authors=3 |last4=Liscum |first4=Laura |last5=Luskey |first5=Kenneth L. |last6=Basu |first6=Sandip K. |last7=Okayama |first7=Hiroto |last8=Berg |first8=Paul |last9=Goldstein |first9=Joseph L.}}
* {{저널 인용|vauthors=Russell DW, Schneider WJ, Yamamoto T, Luskey KL, Brown MS, Goldstein JL |title=Domain map of the LDL receptor: sequence homology with the epidermal growth factor precursor |journal=Cell |volume=37 |issue=2 |pages=577–85 |date=Jun 1984 |pmid=6327078 |doi= 10.1016/0092-8674(84)90388-X|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(84)90388-X}}
* {{저널 인용|author=Reynolds GA |title=HMG CoA reductase: a negatively regulated gene with unusual promoter and 5' untranslated regions |journal=Cell |volume=38 |issue=1 |pages=275–85 |date=Aug 1984 |pmid=6088070 |doi= 10.1016/0092-8674(84)90549-X|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(84)90549-X |name-list-format=vanc|author2=Basu SK |author3=Osborne TF |display-authors=3 |last4=Chin |first4=Daniel J. |last5=Gil |first5=Gregorio |last6=Brown |first6=Michael S. |last7=Goldstein |first7=Joseph L. |last8=Luskey |first8=Kenneth L.}}
* {{저널 인용|author=Yamamoto T |title=The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA |journal=Cell |volume=39 |issue=1 |pages=27–38 |date=Nov 1984 |pmid=6091915 |doi= 10.1016/0092-8674(84)90188-0|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(84)90188-0 |name-list-format=vanc|author2=Davis CG |author3=Brown MS |display-authors=3 |last4=Schneider |first4=Wolfgang J. |last5=Casey |first5=M.Linette |last6=Goldstein |first6=Joseph L. |last7=Russell |first7=David W.}}
* {{저널 인용|vauthors=Lehrman MA, Schneider WJ, Südhof TC, Brown MS, Goldstein JL, Russell DW |title=Mutation in LDL receptor: Alu-Alu recombination deletes exons encoding transmembrane and cytoplasmic domains |journal=Science |volume=227 |issue=4683 |pages=140–6 |date=Jan 1985 |pmid=3155573 |doi= 10.1126/science.3155573|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=3155573}}
* {{저널 인용|vauthors=Südhof TC, Goldstein JL, Brown MS, Russell DW |title=The LDL receptor gene: a mosaic of exons shared with different proteins |journal=Science |volume=228 |issue=4701 |pages=815–22 |date=May 1985 |pmid=2988123 |doi= 10.1126/science.2988123|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=2988123}}
* {{저널 인용|vauthors=Südhof TC, Russell DW, Goldstein JL, Brown MS, Sanchez-Pescador R, Bell GI |title=Cassette of eight exons shared by genes for LDL receptor and EGF precursor |journal=Science |volume=228 |issue=4701 |pages=893–5 |date=May 1985 |pmid=3873704 |doi= 10.1126/science.3873704|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=3873704}}
* {{저널 인용|vauthors=Gil G, Faust JR, Chin DJ, Goldstein JL, Brown MS |title=Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme |journal=Cell |volume=41 |issue=1 |pages=249–58 |date=May 1985 |pmid=3995584 |doi= 10.1016/0092-8674(85)90078-9|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(85)90078-9}}
* {{저널 인용|vauthors=Lehrman MA, Goldstein JL, Brown MS, Russell DW, Schneider WJ |title=Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain |journal=Cell |volume=41 |issue=3 |pages=735–43 |date=Jul 1985 |pmid=3924410 |doi= 10.1016/S0092-8674(85)80054-4|url=http://linkinghub.elsevier.com/retrieve/pii/S0092-8674(85)80054-4}}
* {{저널 인용|vauthors=Osborne TF, Goldstein JL, Brown MS |title=5' end of HMG CoA reductase gene contains sequences responsible for cholesterol-mediated inhibition of transcription |journal=Cell |volume=42 |issue=1 |pages=203–12 |date=Aug 1985 |pmid=3860301 |doi= 10.1016/S0092-8674(85)80116-1|url=http://linkinghub.elsevier.com/retrieve/pii/S0092-8674(85)80116-1}}
* {{저널 인용|vauthors=Brown MS, Goldstein JL |title=Scavenger cell receptor shared |journal=Nature |volume=316 |issue=6030 |pages=680–1 |year=1985 |pmid=4033768 |doi= 10.1038/316680a0|url=}}
* {{저널 인용|vauthors=Brown MS, Goldstein JL |title=A receptor-mediated pathway for cholesterol homeostasis |journal=Science |volume=232 |issue=4746 |pages=34–47 |date=Apr 1986 |pmid=3513311 |doi= 10.1126/science.3513311|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=3513311}}
* {{저널 인용|vauthors=Davis CG, Lehrman MA, Russell DW, Anderson RG, Brown MS, Goldstein JL |title=The J.D. mutation in familial hypercholesterolemia: amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors |journal=Cell |volume=45 |issue=1 |pages=15–24 |date=Apr 1986 |pmid=3955657 |doi= 10.1016/0092-8674(86)90533-7|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(86)90533-7}}
* {{저널 인용|vauthors=Yamamoto T, Bishop RW, Brown MS, Goldstein JL, Russell DW |title=Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit |journal=Science |volume=232 |issue=4755 |pages=1230–7 |date=Jun 1986 |pmid=3010466 |doi= 10.1126/science.3010466|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=3010466}}
* {{저널 인용|vauthors=Lehrman MA, Goldstein JL, Russell DW, Brown MS |title=Duplication of seven exons in LDL receptor gene caused by Alu-Alu recombination in a subject with familial hypercholesterolemia |journal=Cell |volume=48 |issue=5 |pages=827–35 |date=Mar 1987 |pmid=3815525 |doi= 10.1016/0092-8674(87)90079-1|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(87)90079-1}}
* {{저널 인용|vauthors=Südhof TC, Russell DW, Brown MS, Goldstein JL |title=42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter |journal=Cell |volume=48 |issue=6 |pages=1061–9 |date=Mar 1987 |pmid=3030558 |doi= 10.1016/0092-8674(87)90713-6|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(87)90713-6}}
* {{저널 인용|vauthors=Davis CG, Goldstein JL, Südhof TC, Anderson RG, Russell DW, Brown MS |title=Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region |journal=Nature |volume=326 |issue=6115 |pages=760–5 |year=1987 |pmid=3494949 |doi=10.1038/326760a0 |url=}}
* {{저널 인용|vauthors=Hofmann SL, Russell DW, Brown MS, Goldstein JL, Hammer RE |title=Overexpression of low density lipoprotein (LDL) receptor eliminates LDL from plasma in transgenic mice |journal=Science |volume=239 |issue=4845 |pages=1277–81 |date=Mar 1988 |pmid=3344433 |doi= 10.1126/science.3344433|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=3344433}}
* {{저널 인용|vauthors=Reiss Y, Goldstein JL, Seabra MC, Casey PJ, Brown MS |title=Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides |journal=Cell |volume=62 |issue=1 |pages=81–8 |date=Jul 1990 |pmid=2194674 |doi= 10.1016/0092-8674(90)90242-7|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(90)90242-7}}
* {{저널 인용|vauthors=Yokode M, Hammer RE, Ishibashi S, Brown MS, Goldstein JL |title=Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors |journal=Science |volume=250 |issue=4985 |pages=1273–5 |date=Nov 1990 |pmid=2244210 |doi= 10.1126/science.2244210|url=http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=2244210}}
* {{저널 인용|vauthors=Seabra MC, Reiss Y, Casey PJ, Brown MS, Goldstein JL |title=Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit |journal=Cell |volume=65 |issue=3 |pages=429–34 |date=May 1991 |pmid=2018975 |doi= 10.1016/0092-8674(91)90460-G|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(91)90460-G}}
* {{저널 인용|vauthors=Chen WJ, Andres DA, Goldstein JL, Russell DW, Brown MS |title=cDNA cloning and expression of the peptide-binding beta subunit of rat p21ras farnesyltransferase, the counterpart of yeast DPR1/RAM1 |journal=Cell |volume=66 |issue=2 |pages=327–34 |date=Jul 1991 |pmid=1855253 |doi= 10.1016/0092-8674(91)90622-6|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(91)90622-6}}
* {{저널 인용|vauthors=Seabra MC, Brown MS, Slaughter CA, Südhof TC, Goldstein JL |title=Purification of component A of Rab geranylgeranyl transferase: possible identity with the choroideremia gene product |journal=Cell |volume=70 |issue=6 |pages=1049–57 |date=Sep 1992 |pmid=1525821 |doi= 10.1016/0092-8674(92)90253-9|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(92)90253-9}}
* {{저널 인용|vauthors=Brown MS, Goldstein JL |title=Koch's postulates for cholesterol |journal=Cell |volume=71 |issue=2 |pages=187–8 |date=Oct 1992 |pmid=1423585 |doi= 10.1016/0092-8674(92)90346-E|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(92)90346-E}}
* {{저널 인용|author=Andres DA |title=cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein |journal=Cell |volume=73 |issue=6 |pages=1091–9 |date=Jun 1993 |pmid=8513495 |doi= 10.1016/0092-8674(93)90639-8|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(93)90639-8 |name-list-format=vanc|author2=Seabra MC |author3=Brown MS |display-authors=3 |last4=Armstrong |first4=Scott A. |last5=Smeland |first5=Tor E. |last6=Cremers |first6=Frans P.M. |last7=Goldstein |first7=Joseph L.}}
* {{저널 인용|author=Yokoyama C |title=SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene |journal=Cell |volume=75 |issue=1 |pages=187–97 |date=Oct 1993 |pmid=8402897 |doi= 10.1016/S0092-8674(05)80095-9 |name-list-format=vanc|author2=Wang X |author3=Briggs MR |display-authors=3 |last4=Admon |first4=A |last5=Wu |first5=J |last6=Hua |first6=X |last7=Goldstein |first7=JL |last8=Brown |first8=MS}}
* {{저널 인용|vauthors=Garcia CK, Goldstein JL, Pathak RK, Anderson RG, Brown MS |title=Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle |journal=Cell |volume=76 |issue=5 |pages=865–73 |date=Mar 1994 |pmid=8124722 |doi= 10.1016/0092-8674(94)90361-1|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(94)90361-1}}
* {{저널 인용|vauthors=Wang X, Sato R, Brown MS, Hua X, Goldstein JL |title=SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis |journal=Cell |volume=77 |issue=1 |pages=53–62 |date=Apr 1994 |pmid=8156598 |doi= 10.1016/0092-8674(94)90234-8|url=http://linkinghub.elsevier.com/retrieve/pii/0092-8674(94)90234-8}}
* {{저널 인용|vauthors=Sakai J, Duncan EA, Rawson RB, Hua X, Brown MS, Goldstein JL |title=Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment |journal=Cell |volume=85 |issue=7 |pages=1037–46 |date=Jun 1996 |pmid=8674110 |doi= 10.1016/S0092-8674(00)81304-5|url=http://linkinghub.elsevier.com/retrieve/pii/S0092-8674(00)81304-5}}
* {{저널 인용|vauthors=Hua X, Nohturfft A, Goldstein JL, Brown MS |title=Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein |journal=Cell |volume=87 |issue=3 |pages=415–26 |date=Nov 1996 |pmid=8898195 |doi= 10.1016/S0092-8674(00)81362-8|url=http://linkinghub.elsevier.com/retrieve/pii/S0092-8674(00)81362-8}}
* {{저널 인용|vauthors=Brown MS, Goldstein JL |title=The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor |journal=Cell |volume=89 |issue=3 |pages=331–40 |date=May 1997 |pmid=9150132 |doi= 10.1016/S0092-8674(00)80213-5|url=http://linkinghub.elsevier.com/retrieve/pii/S0092-8674(00)80213-5}}
* {{저널 인용|vauthors=DeBose-Boyd RA, Brown MS, Li WP, Nohturfft A, Goldstein JL, Espenshade PJ |title=Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi |journal=Cell |volume=99 |issue=7 |pages=703–12 |date=Dec 1999 |pmid=10619424 |doi= 10.1016/S0092-8674(00)81668-2|url=http://linkinghub.elsevier.com/retrieve/pii/S0092-8674(00)81668-2}}
* {{저널 인용|vauthors=Brown MS, Ye J, Rawson RB, Goldstein JL |title=Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans |journal=Cell |volume=100 |issue=4 |pages=391–8 |date=Feb 2000 |pmid=10693756 |doi= 10.1016/S0092-8674(00)80675-3|url=http://linkinghub.elsevier.com/retrieve/pii/S0092-8674(00)80675-3}}
* {{저널 인용|vauthors=Nohturfft A, Yabe D, Goldstein JL, Brown MS, Espenshade PJ |title=Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes |journal=Cell |volume=102 |issue=3 |pages=315–23 |date=Aug 2000 |pmid=10975522 |doi= 10.1016/S0092-8674(00)00037-4|url=http://linkinghub.elsevier.com/retrieve/pii/S0092-8674(00)00037-4}}
* {{저널 인용|author=Yang T |title=Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER |journal=Cell |volume=110 |issue=4 |pages=489–500 |date=Aug 2002 |pmid=12202038 |doi= 10.1016/S0092-8674(02)00872-3|url=http://linkinghub.elsevier.com/retrieve/pii/S0092867402008723 |name-list-format=vanc|author2=Espenshade PJ |author3=Wright ME |display-authors=3 |last4=Yabe |first4=Daisuke |last5=Gong |first5=Yi |last6=Aebersold |first6=Ruedi |last7=Goldstein |first7=Joseph L. |last8=Brown |first8=Michael S.}}
{{colend}}

== 각주 ==
<references/>

== 외부 링크 ==
{{위키공용분류-줄}}
* {{언어링크|en}} [https://www.nobelprize.org/nobel_prizes/medicine/laureates/1985/brown-bio.html The Nobel Prize in Physiology or Medicine 1985 - Michael S. Brown] - 노벨 재단

{{노벨 생리 의학상 수상자}}
{{1985년 노벨상 수상자}}
{{전거 통제}}

{{기본정렬:브라운, 마이클 스튜어트}}

[[분류:1941년 출생]]
[[분류:살아있는 사람]]
[[분류:미국의 유전학자]]
[[분류:미국의 노벨상 수상자]]
[[분류:노벨 생리학·의학상 수상자]]
[[분류:왕립학회 외국인 회원]]
[[분류:펜실베이니아 대학교 동문]]
[[분류:텍사스 대학교 교수]]
[[분류:브루클린 출신]]
[[분류:앨버트 래스커 기초 의학 연구상 수상자]]
[[분류:루이자 그로스 호르위츠상 수상자]]