{{위키데이터 속성 추적}}
'''하이드록시카복실산 수용체 1'''({{llang|en|hydroxycarboxylic acid receptor 1}}, '''HCA<sub>1</sub>''')은 사람에서 HCAR1 [[유전자]]에 의해 암호화되는 [[단백질]]이다.<ref name="entrez">{{웹 인용| title = Entrez Gene: GPR81 G protein-coupled receptor 81| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27198}}</ref><ref name="pmid11574155">{{저널 인용| vauthors = Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF | title = Discovery and mapping of ten novel G protein-coupled receptor genes | journal = Gene | volume = 275 | issue = 1 | pages = 83–91 | date = September 2001 | pmid = 11574155 | doi = 10.1016/S0378-1119(01)00651-5 }}</ref> 이전에는 '''G 단백질 연결 수용체 81'''({{llang|en|G protein-coupled receptor 81}}, '''GPR81''')로 알려졌었다. 하이드록시카복실산 수용체 1(HCA<sub>1</sub>)은 서로 다른 [[하이드록시카복실산 수용체]]인 [[하이드록시카복실산 수용체 2]](HCA<sub>2</sub>) 및 [[하이드록시카복실산 수용체 3]](HCA<sub>3</sub>)과 마찬가지로 [[Gi 단백질 α 소단위체|G<sub>i/o</sub>-연결]] [[G 단백질 연결 수용체]](GPCR)이다.<ref name="IUPHAR's comprehensive 2011 review on HCARs" /><ref name="IUPHAR-DB HCAR family page" /> 하이드록시카복실산 수용체 1()의 주요 [[내인성]] [[작용제]]는 [[젖산]](및 그 [[짝염기]]인 젖산염)이다.<ref name="IUPHAR's comprehensive 2011 review on HCARs">{{저널 인용| vauthors = Offermanns S, Colletti SL, Lovenberg TW, Semple G, Wise A, IJzerman AP | title = International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B) | journal = Pharmacological Reviews | volume = 63 | issue = 2 | pages = 269–90 | date = June 2011 | pmid = 21454438 | doi = 10.1124/pr.110.003301 | doi-access = free }}</ref><ref name="IUPHAR-DB HCAR family page">{{웹 인용|author1=S Offermanns, SL Colletti, AP IJzerman, TW Lovenberg, G Semple, A Wise, MG Waters |title=Hydroxycarboxylic acid receptors |url=http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=48 |website=IUPHAR/BPS Guide to Pharmacology |publisher=International Union of Basic and Clinical Pharmacology |access-date=13 July 2018}}</ref>

== 같이 보기 ==
* [[하이드록시카복실산]]
* [[하이드록시카복실산 수용체]]
* [[하이드록시카복실산 수용체 2]]
* [[하이드록시카복실산 수용체 3]]

== 각주 ==
{{각주}}

== 더 읽을거리 ==
{{참고 자료 시작| 2}}
* {{저널 인용| vauthors = Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S | title = Identification of G protein-coupled receptor genes from the human genome sequence | journal = FEBS Letters | volume = 520 | issue = 1–3 | pages = 97–101 | date = June 2002 | pmid = 12044878 | doi = 10.1016/S0014-5793(02)02775-8 | s2cid = 7116392 | doi-access = free }}
* {{저널 인용| vauthors = Mao M, Biery MC, Kobayashi SV, Ward T, Schimmack G, Burchard J, Schelter JM, Dai H, He YD, Linsley PS | title = T lymphocyte activation gene identification by coregulated expression on DNA microarrays | journal = Genomics | volume = 83 | issue = 6 | pages = 989–99 | date = June 2004 | pmid = 15177553 | doi = 10.1016/j.ygeno.2003.12.019 }}
* {{저널 인용| vauthors = Madaan A, Nadeau-Vallée M, Rivera JC, Obari D, Hou X, Sierra EM, Girard S, Olson DM, Chemtob S | title = Lactate produced during labor modulates uterine inflammation via GPR81&nbsp;(HCA1) | journal = American Journal of Obstetrics and Gynecology | date = September 2016 | volume = 216 | issue = 1 | pages = 60.e1–60.e17 | pmid = 27615440 | doi = 10.1016/j.ajog.2016.09.072 | doi-access = free }}
{{참고 자료 끝}}

[[분류:인간 12번 염색체상 유전자]]
[[분류:G 단백질 연결 수용체]]