{{위키데이터 속성 추적}}
{{유전자 정보}}

'''IGL@'''(Immunoglobulin lambda locus)은 인간 22번 [[염색체]]에 위치한 영역이며, 항체의 람다 [[경쇄]]에 대한 [[유전자]]를 포함하고 있다.<ref name="entrez">{{웹 인용|url=https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3535|title=Entrez Gene: IGL@ immunoglobulin lambda locus}}</ref>

== 유전자 ==

IGL@는 다음과 같은 유전자를 포함하고 있다.
* IGLC@ – C
** IGLC1 – immunoglobulin lambda constant 1
** IGLC2 – immunoglobulin lambda constant 2
** IGLC3 – immunoglobulin lambda constant 3
** IGLC7 – immunoglobulin lambda constant 7
* IGLJ@ – J
** IGLJn – immunoglobulin lambda joining n
** IGLJ1, IGLJ2, IGLJ3, IGLJ6, IGLJ7
* IGLV@ – V
** IGLVm-n – immunoglobulin lambda variable n-m
** IGLV1-36, IGLV1-40, IGLV1-44, IGLV1-47, IGLV1-51, IGLV1-62
** IGLV2-5, IGLV2-8, IGLV2-11, IGLV2-14, IGLV2-18, IGLV2-23
** IGLV3-1, IGLV3-10, IGLV3-12, IGLV3-16, IGLV3-19, IGLV3-21, IGLV3-25, IGLV3-27
** IGLV4-3, IGLV4-60, IGLV4-69
** IGLV5-37, IGLV5-39, IGLV5-45, IGLV5-52
** IGLV6-57
** IGLV7-43
** IGLV9-49
** IGLV10-54
'''Ig lambda chain C regions'''은 인간의 IGLC2 유전자에 의해 암호화되는 [[단백질]]이다.<ref name="entrez" />

== 각주 ==
{{각주}}

== 참고 문헌 ==
{{참고 자료 시작| 2}}
*{{저널 인용| author=Taussig MJ |title=Molecular genetics of immunoglobulins. |journal=Immunology. Supplement |volume=1 |pages= 7–15 |year= 1988 |pmid= 3133312 }}
*{{저널 인용|vauthors=Combriato G, Klobeck HG |title=V lambda and J lambda-C lambda gene segments of the human immunoglobulin lambda light chain locus are separated by 14 kb and rearrange by a deletion mechanism. |journal=Eur. J. Immunol. |volume=21 |issue= 6 |pages= 1513–22 |year= 1991 |pmid= 1904362 |doi=10.1002/eji.1830210627  |s2cid=84668650 }}
*{{저널 인용|vauthors=Vasicek TJ, Leder P |title=Structure and expression of the human immunoglobulin lambda genes. |journal=J. Exp. Med. |volume=172 |issue= 2 |pages= 609–20 |year= 1990 |pmid= 2115572 |doi=10.1084/jem.172.2.609  | pmc=2188323  }}
*{{저널 인용|vauthors=Emanuel BS, Cannizzaro LA, Magrath I, etal |title=Chromosomal orientation of the lambda light chain locus: V lambda is proximal to C lambda in 22q11. |journal=Nucleic Acids Res. |volume=13 |issue= 2 |pages= 381–7 |year= 1985 |pmid= 3923432 |doi=10.1093/nar/13.2.381  | pmc=341002  }}
*{{저널 인용|vauthors=Hieter PA, Korsmeyer SJ, Waldmann TA, Leder P |title=Human immunoglobulin kappa light-chain genes are deleted or rearranged in lambda-producing B cells. |journal=Nature |volume=290 |issue= 5805 |pages= 368–72 |year= 1981 |pmid= 6783958 |doi=10.1038/290368a0  |bibcode=1981Natur.290..368H |s2cid=4333721 }}
*{{저널 인용|vauthors=Erikson J, Martinis J, Croce CM |title=Assignment of the genes for human lambda immunoglobulin chains to chromosome 22. |journal=Nature |volume=294 |issue= 5837 |pages= 173–5 |year= 1982 |pmid= 6795508 |doi=10.1038/294173a0  |s2cid=22056008 }}
*{{저널 인용|vauthors=McBride OW, Hieter PA, Hollis GF, etal |title=Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes. |url=https://archive.org/details/sim_journal-of-experimental-medicine_1982-05_155_5/page/1480 |journal=J. Exp. Med. |volume=155 |issue= 5 |pages= 1480–90 |year= 1982 |pmid= 6802926 |doi=10.1084/jem.155.5.1480  | pmc=2186665  }}
*{{저널 인용|vauthors=Frippiat JP, Williams SC, Tomlinson IM, etal |title=Organization of the human immunoglobulin lambda light-chain locus on chromosome 22q11.2. |journal=Hum. Mol. Genet. |volume=4 |issue= 6 |pages= 983–91 |year= 1995 |pmid= 7655473 |doi=10.1093/hmg/4.6.983  }}
*{{저널 인용|vauthors=Williams SC, Frippiat JP, Tomlinson IM, etal |title=Sequence and evolution of the human germline V lambda repertoire. |journal=J. Mol. Biol. |volume=264 |issue= 2 |pages= 220–32 |year= 1997 |pmid= 8951372 |doi= 10.1006/jmbi.1996.0636 }}
*{{저널 인용|vauthors=Kawasaki K, Minoshima S, Nakato E, etal |title=One-megabase sequence analysis of the human immunoglobulin lambda gene locus. |journal=Genome Res. |volume=7 |issue= 3 |pages= 250–61 |year= 1997 |pmid= 9074928 |doi=10.1101/gr.7.3.250  |doi-access=free }}
*{{저널 인용| author=Lefranc MP |title=Nomenclature of the human immunoglobulin lambda (IGL) genes. |journal=Exp. Clin. Immunogenet. |volume=18 |issue= 4 |pages= 242–54 |year= 2002 |pmid= 11872955 |doi=10.1159/000049203  |s2cid=27255400 }}
*{{저널 인용|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |doi-access=free }}
*{{저널 인용|vauthors=Boursier L, Su W, Spencer J |title=Imprint of somatic hypermutation differs in human immunoglobulin heavy and lambda chain variable gene segments. |journal=Mol. Immunol. |volume=39 |issue= 16 |pages= 1025–34 |year= 2003 |pmid= 12749909 |doi=10.1016/S0161-5890(03)00033-6  }}
*{{저널 인용|vauthors=Makino DL, Henschen-Edman AH, McPherson A |title=Four crystal forms of a Bence-Jones protein. |journal=Acta Crystallographica Section F |volume=61 |issue= Pt 1 |pages= 79–82 |year= 2006 |pmid= 16508097 |doi= 10.1107/S1744309104028532  | pmc=1952397 }}
*{{저널 인용|vauthors=Richl P, Stern U, Lipsky PE, Girschick HJ |title=The lambda gene immunoglobulin repertoire of human neonatal B cells. |journal=Mol. Immunol. |volume=45 |issue= 2 |pages= 320–7 |year= 2007 |pmid= 17675156 |doi= 10.1016/j.molimm.2007.06.155 }}
{{참고 자료 끝}}

{{항체}}

[[분류:항체]]
[[분류:단백질]]