{{위키데이터 속성 추적}}
{{Infobox medical condition (new)
| name            = 저연령대 성숙기발병당뇨병
| synonyms        = 단일유전자 당뇨병
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| field           = [[내분비내과]]
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'''저연령대 성숙기발병당뇨병'''(maturity-onset diabetes of the young, '''MODY''')<ref>{{뉴스 인용|title=What is maturity-onset diabetes of the young (MODY)? |publisher=National Institute of Diabetes and Digestive and Kidney Diseases, NIH |url=http://www.diabetes.niddk.nih.gov/dm/pubs/mody/#3 |work=National Diabetes Information Clearinghouse (NDIC) |access-date=2008-07-29 |archive-url=https://web.archive.org/web/20080704103703/http://diabetes.niddk.nih.gov/dm/pubs/mody/#3 |archive-date=2008-07-04 |url-status=dead}}</ref>은 [[인슐린]]의 생산을 방해하는 [[상염색체 우성]] 유전자의 [[돌연변이]]로 인해 발생하는 모든 종류의 [[유전병|유전성]] [[당뇨병]]을 가리키는 용어이다.<ref name="GoldsteinMüller-Wieland2008">{{서적 인용|author1=Barry J. Goldstein|author2=Dirk Müller-Wieland|title=Type 2 diabetes: principles and practice|url=https://books.google.com/books?id=1NHv7Iwx5AcC&pg=PA529|access-date=12 June 2010|year=2008|publisher=CRC Press|isbn=978-0-8493-7957-4|pages=529–}}</ref> [[제1형 당뇨병]]이나 [[제2형 당뇨병]]과 같이 여러 가지 유전자와 [[환경 인자]]가 관여하는 더 흔한 종류의 당뇨병과 구분하기 위해 MODY를 '''단일유전자 당뇨병'''(monogenic diabetes)이라고도 부른다.<ref name="pmid15181075">{{저널 인용|last=Yorifuji|first=T|author2=Kurokawa, K |author3=Mamada, M |author4=Imai, T |author5=Kawai, M |author6=Nishi, Y |author7=Shishido, S |author8=Hasegawa, Y |author9= Nakahata, T  |title=Neonatal diabetes mellitus and neonatal polycystic, dysplastic kidneys: Phenotypically discordant recurrence of a mutation in the hepatocyte nuclear factor-1beta gene due to germline mosaicism.|journal=The Journal of Clinical Endocrinology and Metabolism|date=June 2004|volume=89|issue=6|pages=2905–8|pmid=15181075|doi=10.1210/jc.2003-031828|doi-access=free}}</ref><ref name="pmid17116179">{{저널 인용|last=Edghill|first=EL|author2=Bingham, C |author3=Slingerland, AS |author4=Minton, JA |author5=Noordam, C |author6=Ellard, S |author7= Hattersley, AT |title=Hepatocyte nuclear factor-1 beta mutations cause neonatal diabetes and intrauterine growth retardation: support for a critical role of HNF-1beta in human pancreatic development|journal=Diabetic Medicine|date=December 2006|volume=23|issue=12|pages=1301–6|pmid=17116179|doi=10.1111/j.1464-5491.2006.01999.x|s2cid=41113543}}</ref> 가장 흔한 종류는 [[MODY 2]]와 [[MODY 3]]이다.<ref>This page has previously claimed that MODY is equivalent to type 1 DM; however, the [[Oxford Handbook of Clinical Medicine]] states the above.</ref>

로버트 테터솔(Robert Tattersall)과 스테판 파잔스(Stefan Fajans)가 1975년 저널 "[[다이아비티스 (학술지)|Diabetes]]"에 출판된 연구에서 처음으로 저연령대 성숙기발병당뇨병이라는 현상을 처음으로 확인하였다.<ref>{{웹 인용|last1=Chennai, India |first1=Dr. V Mohan |title='Maturity Onset Diabetes of the Young (MODY) {{!}} Dr Mohans |url=https://drmohans.com/what-is-maturity-onset-diabetes-of-the-young-mody/ |website=Dr Mohan's Diabetes Center in Chennai |date=2020-07-15}}</ref>

== 각주 ==
{{각주}}

== 외부 링크 ==
{{Medical resources
|  DiseasesDB      = 8330
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|  ICDO            = 
|  OMIM            = 606391
|  MedlinePlus     = 
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|  eMedicineTopic  = 
|  MeshID          = D003924
}}

[[분류:당뇨병]]
[[분류:선천성 질환]]