{{위키데이터 속성 추적}}
{{Chembox
| name = 다이하이드로프테로산
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 460787515
| ImageFile = Dihydropteroic acid.svg
| ImageSize = 
| IUPACName = 4-<nowiki/>{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoic acid
| OtherNames = 
|Section1={{Chembox Identifiers
| Abbreviations = 
| InChI = 1/C14H14N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,16H,5-6H2,(H,22,23)(H4,15,17,19,20,21)
| InChIKey = WBFYVDCHGVNRBH-UHFFFAOYAH
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C14H14N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,16H,5-6H2,(H,22,23)(H4,15,17,19,20,21)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = WBFYVDCHGVNRBH-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|changed|??}}
| CASNo = 2134-76-1
| EINECS = 
| PubChem = 170
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 165
| SMILES1 = O=C(O)c1ccc(cc1)NCC/2=N/C=3C(=O)\N=C(/NC=3NC\2)N
| SMILES2 = C1C(=NC2=C(N1)NC(=NC2=O)N)CNC3=CC=C(C=C3)C(=O)O
| RTECS =
| MeSHName =
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 4581
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = C00921
| Beilstein = 1226443
}}
|Section2={{Chembox Properties
| Formula = C<sub>14</sub>H<sub>14</sub>N<sub>6</sub>O<sub>3</sub>
| MolarMass = 314.3 g/mol
| Appearance =
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|Section3={{Chembox Structure
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|Section4={{Chembox Thermochemistry
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|Section5={{Chembox Pharmacology
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|Section6={{Chembox Explosive
| ShockSens = 
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|Section7={{Chembox Hazards
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|Section8={{Chembox Related
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}}

'''다이하이드로프테로산'''({{llang|en|dihydropteroate}})은 [[폴산]] 합성의 중요한 [[대사 중간생성물]]이다. 다이하이드로프테로산은 [[다이하이드로프테로산 생성효소]]에 의해 [[파라-아미노벤조산]](PABA)로부터 생성되는 [[프테린]]이다.<ref>{{저널 인용|title=Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase|journal=Journal of Medicinal Chemistry|volume=53|issue=1|pages=166–177|doi=10.1021/jm900861d|pmid=19899766|pmc=2804029|year=2010|last1=Hevener|first1=Kirk E|last2=Yun|first2=Mi-Kyung|last3=Qi|first3=Jianjun|last4=Kerr|first4=Iain D|last5=Babaoglu|first5=Kerim|last6=Hurdle|first6=Julian G|last7=Balakrishna|first7=Kanya|last8=White|first8=Stephen W|last9=Lee|first9=Richard E}}</ref>
{|
|[[파일:THFsynthesispathway.png|섬네일|왼쪽|450px|[[테트라하이드로폴산]] 합성 경로]]
|}

설폰아마이드와 같은 정균제는 다이하이드로프테로산 생성효소를 표적으로 한다. 다이하이드로프테로산 생성효소의 저해 효과는 또 다른 정균제인 트라이메토프림에 의한 다이하이드로폴산 환원효소의 저해 효과와 비슷하다. [[트라이메토프림/설파메톡사졸]](TMP-SMX) 조합과 같은 이 두 가지 유형의 약물 조합은 일반적으로 재발성 요로, [[이질균]], [[살모넬라]] 및 기포자충(''Pneumocystis jivoreci'') 감염을 치료하는 데 사용된다.

== 같이 보기 ==
* [[다이하이드로폴산]]

== 각주 ==
{{각주}}

[[분류:벤조산]]
[[분류:폴산]]