{{위키데이터 속성 추적}}
[[파일:Chemical Genomics Robot.jpg|섬네일|220px|고속대량 스크리닝 로봇]]
'''고속대량 스크리닝'''({{llang|en|high-throughput screening}}, '''HTS''')은 특히 [[약물 발견]]에 사용되며 [[생물학]], [[재료과학]]<ref>{{저널 인용|title=A bilayer conducting polymer structure for planar perovskite solar cells with over 1,400 hours operational stability at elevated temperatures|journal=Nature Energy|last1=Zhao|first1=Yicheng|last2=Heumueller|first2=Thomas|date=16 December 2021|volume=7|issue=2|pages=144–152|language=en|bibcode=2022NatEn...7..144Z|doi=10.1038/s41560-021-00953-z|issn=2058-7546|last3=Zhang|first3=Jiyun|last4=Luo|first4=Junsheng|last5=Kasian|first5=Olga|last6=Langner|first6=Stefan|last7=Kupfer|first7=Christian|last8=Liu|first8=Bowen|last9=Zhong|first9=Yu|last10=Elia|first10=Jack|last11=Osvet|first11=Andres|last12=Wu|first12=Jianchang|last13=Liu|first13=Chao|last14=Wan|first14=Zhongquan|last15=Jia|first15=Chunyang|last16=Li|first16=Ning|last17=Hauch|first17=Jens|last18=Brabec|first18=Christoph J.|s2cid=245285868}}</ref> 및 [[화학]] 분야와 관련된 과학적 [[실험]] 방법이다.<ref>Inglese J and Auld DS. (2009) Application of High Throughput Screening (HTS) Techniques: Applications in Chemical Biology in Wiley Encyclopedia of Chemical Biology (Wiley & Sons, Inc., Hoboken, NJ) Vol 2, pp 260–274  doi/10.1002/9780470048672.wecb223.</ref><ref>{{저널 인용| title = Impact of high-throughput screening in biomedical research |author1 = Macarron, R. |author2 = Banks, M.N.|author3 = Bojanic, D.| author4 = Burns, D.J.|author5 = Cirovic, D.A.|author6 = Garyantes, T.|author7 = Green, D.V.| author8 = Hertzberg, R.P. |author9 = Janzen, W.P.|author10 = Paslay, J.W.|author11 = Schopfer, U.| author12 = Sittampalam, G.S. | journal = Nat Rev Drug Discov|date = 2011 |volume = 10|issue = 3 |pages = 188–195|pmid = 21358738 | doi = 10.1038/nrd3368|s2cid = 205477370 }}</ref> [[로봇공학]], 데이터 처리/제어 소프트웨어, 액체 취급 장치 및 민감한 검출기를 사용하는 고속대량 스크리닝을 통해 연구자는 수백만 건의 화학, 유전학 또는 약리학 테스트를 신속하게 수행할 수 있다. 이 과정을 통해 특정 생체분자 경로를 조절하는 활성 화합물, 항체 또는 유전자를 신속하게 인식할 수 있다. 이러한 실험의 결과는 약물 설계 및 비상호작용 또는 특정 위치의 역할을 이해하기 위한 출발점을 제공한다.

== 같이 보기 ==
* [[약물 발견]]

== 각주 ==
{{각주}}

== 더 읽을거리 ==
<!-- items in this section may be promoted to references through use of information from them in the article -->
*{{저널 인용|last1=Lin|first1=Yibin|title=What's happened over the last five years with high-throughput protein crystallization screening?|journal=Expert Opinion on Drug Discovery|volume=13|issue=8|year=2018|pages=691–695|issn=1746-0441|doi=10.1080/17460441.2018.1465924|pmid=29676184|doi-access=free}}
* {{뉴스 인용| last =Staff | date =2008-08-01 | title =High-Throughput Screening Challenges
 | periodical =Genetic Engineering & Biotechnology News | series =Drug Discovery Rountable Discussion
 | publisher =Mary Ann Liebert | volume =28 | issue =14 | pages =26&ndash;27
 | url =http://www.genengnews.com/articles/chitem.aspx?aid=2571 | issn =1935-472X | access-date =2008-10-01 }}
* Zhang XHD (2011) [http://www.cambridge.org/9780521734448 "Optimal High-Throughput Screening: Practical Experimental Design and Data Analysis for Genome-scale RNAi Research, Cambridge University Press"]
* {{저널 인용|last1=Florian|first1=Amy|last2=Lepensky|first2=C|last3=Kwon|first3=O|last4=Sklar|first4=L|last5=Haynes|first5=M|title=Flow cytometry enbles a high-throughput homogenous fluorecent antibody-binding assay for cytotoxic T cell lytic granule exocytosis|journal=Journal of Biomolecular Screening|date=201|volume=4|issue=18|pages=420–429|doi=10.1177/1087057112466697|pmid=23160568|pmc=4043149}}<!--|access-date=2015-03-19--> Flow cytometry enables a high-throughput homogeneous fluorescent antibody-binding assay for cytotoxic T cell lytic granule exocytosis
* {{저널 인용|last1=Florian|first1=Amy E.|last2=Lepensky|first2=Christopher K.|last3=Kwon|first3=Ohyun|last4=Haynes|first4=Mark K.|last5=Sklar|first5=Larry A.|last6=Zweifach|first6=Adam|title=Flow Cytometry Enables a High-Throughput Homogeneous Fluorescent Antibody-Binding Assay for Cytotoxic T Cell Lytic Granule Exocytosis|journal=Journal of Biomolecular Screening|volume=18|issue=4|year=2013|pages=420–429|issn=1087-0571|doi=10.1177/1087057112466697|pmid=23160568|pmc=4043149}}

== 외부 링크 ==
* [http://sen.sourceforge.net/ Open Screening Environment]
* [https://web.archive.org/web/20101214123953/http://labmanager.com/articles.asp?ID=481 Setting up High-Throughput Screening Laboratory] (Koppal, Lab Manager Magazine)
* [https://wayback.archive-it.org/all/20121010200014/http://spotlite.nih.gov/assay/index.php/Table_of_Contents Assay Guidance Manual]  (NIH, NCGC)
* [https://www.horizondiscovery.com/research-services/drug-combination-screening/oncosignature-ht-standard-offering OncoSignature High Throughput Screening]

{{전거 통제}}

[[분류:과학적 기술]]
[[분류:조제학]]
[[분류:약물 발견]]