The Sun.
London, England, 1824-09-21 00:00:00

HYDROPHOBIA.

In the following report will be found further
particulars of the lamentable case of hydrophobia
which occurred at Guys Hospital last week, and
a brief account of which was published by us in
THE SuN.of Thursday.
(From the Lancet.)
GUY'S HOSPITAL.—IIYDROruou lA.—A distressing case
of Hydrophobia, and the application of illagendie's Remedy,
for the first time in this country.—Air. D. WO. 27, a young

man, of a muscular, spare habit, was brought into Cornelius'
Ward of this Hospital about ten o'clock last Sunday evening.
On the 23d of July last he was bitten by a dog, just above
the wrist, near Brixton, and was placed under the care of Mr.
Hammond, of that place, who almost immediately excised the
part, and afterwards applied caustic to the wound. The dog
.was at the time suspected of being mad, and great- anxiety' was
felt for the man's safety.
He showed no symptom, however, which could be considered.
alarming until within the last few days. On Friday he com-
plained for the first time of an uneasiness and tightness about
his throat, appeared more irritable than usual and had a rest-
less night. On Saturday he took a cup of coffee for his break-
fast, and swallowed it in a great hurry, as if drinking some-
thing very unpleasant. He had to clean his master's carriage
and water his horses, but he could not summon resolution to
do so, without being able particularly to say why heohjected,
and on the following day he could not drink his tea. Mr. Cal-
laway was called to him, and, considering ' the nature'of the
case, thought it better for him to be brought to the hospital.
Hecomplained of great uneasiness and a feeling of, oppres-
sion about the chest, more particularly in the region of the
diaphragni ; his breathing was hurried and'interrupted by fre-
quent convulsive sighs. His pulse was at this time 90, and
very firm, his skin hot and dry, and he had also considerable
pain in his head, but answered any questions put to him with
great propriety. The spasms were stronger on 'the right
side, and the motions of the right extremities could be with
difficulty restrained. He was exceedingly restless during the
night, and could not bear the least breath of air to play on him,
Or even the friction of a handkerchief to' wipe any part of his skin,
as either of these things happening instantly threw him into via-
lent convulsions; a drop of fluid of any kind falling on his skin
instantly produced the same effect. He took one grain ofopium
and two grains of the super-acetate of lead everfhalf hour;
and towards morning had it given rather more frequently, so
that he took 40 grains of the super-acetate in nine hours ; one of
the gentlemen who sat up with him drew back the curtain to
tee if it were day, when a gleam of light fell on his countenance,
and immediately threw him into convulsions. He was perfectly
conscious of the persons about him, and shook them by the
hand when he saw them again in the morning. lie would,
however start up suddenly in the bed, cry out violently, and
then sink down again as if exhausted; and if asked why he did
so, be would place his hand on his chest and say, he could not
help it, but that it was the wind on his stomach and throaL.....
Ilis pulse throughout the night varied from 84 to 100, some-
times rising or falling ten in a few minutes.
This morning (Monday) he was visited by Dr. Addison, who
thought the case'a confirmed one, and ordered the former me..
dicine to be continued, with the addition of one grain of the
resinous extract of the nux vomica, to be taken every quarter of
an hour; this medicine was continued until Dr. Blundell came,
who had before arranged with Dr. Addison, to try the effect
of injecting the veins with warm water, according to the
mode adopted by 111. Magendie. The medicine he had taken
had, by eleven o'clock in the forenoon, produced a general
feeling of numbness, and he lay, certainly,-quieter than he had
done before.

Dr. Blundell entored the room with a great many of his stu-
dents, and after feeling his pulse; blew suddenly un his face,
which caused him to start up in great agony, and to express
himself very severely against the Doctor fur the torture to which
he had put him. Dr.'l.3lundell said he was perfectly satisfied
as to the nature of the, disease, and that that single circum-
stance might be considered sufficiently patbognomonic. There
appeared, therefore, no time to lose, and it was considered a
fair case fbr the trial of the injection.
The pulse at a quarter before 12 was 100; the countenance
expressed the greatest anxiety, and the breathing, every now
and then, was interrupted by frequent sobs. At 12 the pulse
was 04, and very firm and full. At half past twelve he was
bled, preparatory to the operation, as recommended by Ma-
gendie, anti twenty ounces were ditected to be drawn. Whilst
the blood was flowing, the pulse gradually increased in fre-
quency to 110, and being still very firm, it' was thought ad-
visable to take Off a few ounces more; and instead of this

precaution being attended to, nearly twenty ounces more were
abstracted,. the pulse during the time this wasflowing increased
to 140, making the whole quantity taken 40 ounces, and at the
close his pulse was 160. From the great excitement produced
by the tyrngup of the arm and the bleeding, the patient be-
came almost ungovernable ; threw himself about violently,
and would not suer himself to be held.

Considerable time was lost by not being able to introduce the
tube for the transmission of the injection through the same ori.
Lice at which he was bled.
_Mr. Key then dissected the cepha.
lie vein, about three inches below the bend of the elbow, and
raised it over a probe, then made a longitudinal opening through
the coats on its anterior surface and introduced the tube. The

ing this, with the difficulty there Was in receiving the blood
as it flowed, owing to his extreme restlessness, delayed the time
thalf one.
o , .
Just as the connecting pipe from tne syringe was about to be
attached to the tube already in the vein, the pulsation at the
wrist ceased, and all were of opinion that the remedy arrived
too late; considering, however, that the principle might be ad-
tiered to, it was suggested, that if a stimulant were injected in-
stead of the distilled-water, it might succeed in resuscitating
him ; a few table spoonfuls of diluted spirit, in the proportion
of two-thirds of water to one of spirit, were added to the fluid
prepared fi>r injection, and a small quantity thrown into the
vein by the syringe. The action of the heart was felt a little
more distinctly, and more fluid was thrown in, the whole not
exceeding two ounces. The pulsation of the brachial artery
could be felt, but not so of the radial ; and it was considered
useless to go farther. The vital energy became gradually les-
sened, and at ten minutes before two it was extinct.
The patient manifested not the least disposition to injure any
of die persons about him, but merely cautioned them to keep
out of his reach, fbr fear he might strike them undesignedly
during•his struggles. Ho had a copious secretion of frothy
mucus from the mouth and/awes, and was obliged frequently.
to spit to free himself of it; every motion was performed with
sudden violencel yet appeared to be under the contraltl of the
will. He gave evident proof of his retaining his senses to a few
minuteskbefore his death, when he sunk into the calm of com-
plete exhaustion.

o,cTloheek, andinsp weetioansofeonthdeuebtoedd by ytoolir. placeKe, in
yon 'Tuesday,presence o
atenef
severalhinciargde:nass and
rst pupils.
The examined, and the following reports made
as the dissection proceeded. The external surface of the con.
volutions appeared rather more vascular than usual, and the
congestion appeared rather.more in the arterial than in the yen.
ous vessels ; the anterior arteries of the cerebrum contained
globules of air. On making 4 section of the hemispheres, the"
red points produced by the division of the vessels were more
numerous In the posterior than in the anterior part of the brain.
—ln the lateral ventricles, about three drachms of fluid *ere
found, and there Was air in the veins of the chorold plexuses,
and also in the veins of the corpora striati ; the pineal gland
contained no phosphate of lime. The posterior arteries of. the
cerebrum also contained air.. On turning out the brain, there
were several projecting bony ridges from the sphenoidal fosse,
which felt very sharp ..on the finger being passed over them.—
Two considerable projections Ilse were found on the huller
process of the occiput, one on each side, just abovethe ante:
nor condyloid foramina. By making a Section of the 'thalami
iiervornin opticorum, the left thalamus presented a consider..
able difference of colour from the right; it had a greenish tint,
with a slight shade of yellow. The locus niger, of the same
side, displayed by section a similar apyearance• This appear.
mice had been noticed before by Mr. Key, in a person who died
of tetanus; and in another who died last summer from hydro-
phobia, 'large patches of bony matter were found in the faux
major.; nearly the size of a split kidneybean.
The•spinal marrow was next examined, by carefully sawing
through the arches of the. vertebra; and having cut through
the theca vertebralis, the pia mater was carefully attended to,
and three small• ()Sac deposits were found 'on its surface, in
that part of the canal between the fifth and the.cleventh dorsal
vertebra ; two of these patches were about the size of pins' heads ;
and the other'about the size of the bulb on a common probe. Tile
blood in the sinuses of the medulla spinalis was quite fluid, as
it also was in the sinuses of the brain. No other peculiarity
could be noticed in this part.
The tongue was also examined; but no pustules could be
found about the franum or any other part, as described by Dr.
Xanthos and. others..
The lining membrane or the trachea appeared coated with a
dark.coloured 'discus throughout nearly the whole extent, as ,
did also the membrane lining the bronchial tubes. The mucus
membrane of the stomach appeared of a reddish colour towards
the cardiac extremity,anti: there were large spots of extrave,.
sated blood between this and the muscular coat.
. of the saliva: taken' from, this patient was introduced be.
need' the integument of a dog's thigh, and the animal is pro-
periy secured, that the effects •of the inoculation 'May be
watched.

SEEDS, Sept. 40.
New English R. Clover, pci cwt... 47s 625 78s—fint 941
Old Dii to
New Foreign ditto 6ls 709 845-611e98'
Old ditto ditto 091 41153s—tine 791
New ‘Vbiteditto 57s 74s 77s—fine 86s
Old ditto 33s 48s 63s—fine 945
New Trefoil.. per cwt 6s 13s 142.—fine 19'
Old ditto 4l 9s 15s—fine its •
New Itibgi ass
Ohl ditto • 4ls :Ms 335-6nt 481
English Catraway Seeds 31s 365 395-60."'"I
Foreign ditto
Coriander do. .
7s 6d 9s 109—fine ---6
St.Foin....per yr. 42s 44,-60e 464
Rye-Grass
Pacey ditto
'I
Linseed for feeding
Ditto, lot crushing
CLlalisliatreyNSluesetsdied Seed.. pe-r bushel 5834257
31-1111 'l
:1 63s—fine
et: 64:3;i
Brown ditto
Turnip Seeds 6s 8s 6d—fine 101
Tares ss 4s—tine 81 9.1
Rape Seed .... per last
___.—..........-•

Mutton
NEIVGATE AND LEADENHALL MASKETS, SrPt. 0'
By the Carcasc.
Beef
Lamb, ss 4d to 4s Bd.
2211 i 461 d ttuo 33: 48tdi I
I\7,r,
rakl 00 'dtu
.54
so

SMITHFIELD HAY MARIE'!', SW, 18', 0, 0.1
Old Huy • • 4l los tul to /SI 15s Od--Avetagef 5,
CA
6 Od:
Straw 2l lOs Od to 31 Ss Otl--Averageo g• 1 1
Clover 5l lOs Od to 61 161 Oa—Average, 61 0
ST. JAMES'S. . Cl cdj
0. Hay 81 Ss Od to 51 151 0(1 1 C10nr,31115 6d to 61
New Hayol Os Od to 01 Os Od f Straw 21 es Od to 51 Os"
Nevti ditto..! WIIITECHAPEL.
0311 lOs
os 00,,11 to 51 5011 5014 oodd=rerrna.ggeo: 41 ~::' 061
Os
Straw d—=---Average, 81 -- 0,1
sl 71
Clover 4l 4s Od to 6! lOs o,l_ Averaged --

PRICE OF HOPI, per Cwt., Sept. 20. rs ar•
About 4300 pockets of the new growth of /lops duChare
rived at market, the quality and appearance of whic" Nor
been generally good, and equal to the average of roust
years. The whole have been freely taken oft at the fo"
ing rates :
Kent Pockets .... 925. to 108 s. to I2os. per ewt'
Sussex Pockets .. 84s. to 100 s. to Mts. per swt•
Old Duty laid at 1.55,0n0i•

tis,
.. .is ilil to 3s 41: -Market tau .. —"- of
Middlings... ts ILA to Bs Cd Lambs.... Os Od to 0$
Os Od to Os Od I Shearlings ......
SHEEP SKINS.
Polled
Fells
________

RAWPrdEilSo.ire ~.. "1° 111
est Heifers & Steers, pert:. H
st.
-. 3,2 d to 3f I •Nat each.. 8"

PRICE OF LEATHER.
nit
to
Butts, 50 to 561hs each per 111
Ditto, 54 to .fitilbs each 404
to toy
gladd
Dressing Hides to 19
Coach Hides god to gild
Crop Hides, 35 s o 4olbs for cut ting 164 to ,"4
Ditto .... 45 to 5olbs
"
Calf Skins..S6 to 401bs
Ditto 50 to 70Ibs 244 t" lid
93
Ditto 7O to tiOlbs
Small Seals (Greenland)
ird to I
Large ditto
Tanned Horse Hides
led to '-
Spanish Horse Hides

PRICES OF TALLOW,

Town Tallow 40s Od —s Od
Yellow Russia 37s Od —s ad
White ditto.. 35s till —c Ot'.
Soap ditto.... 341 s Od —I ad
Melting Stuff 30s Od —s Od
Ditto Rough.. 195 otl —s Od

18
P. &c. pert 121 b.--Sept,
Yellow Sony ..... . 1"
Mottled. ...................
Curd ................ 811
Grave 5......... iesOu
.....
Good Do gs ..........

PRICE OF CANDLES, room TaLLow (1"1.1
Price of Candles, per dozen, 8s 6d —Moulds, 101
6tl per dozen allowed for ready

PRICE OF RAW FAT, per Stone of 81 b.--Sept• Ita
Price of Tallow (as rtated by the

COUNTRY MARKET.
GUI Lnrollo• SePt• 18. P
Wbeat, perld 141 Os a 171 Os I Oats, per qr... 11 3s .1
.1211
New ditto l4l Os a 1;110s Barley .
Rye II 16s a 21 Os Beans
Grey Peas, 11 16s ael Os. 1111....„........-4".-11413:

COAL MARKET, SEPT. 20.
Ships at Market. Ships sold
404 Newcastle - .23f
12 Sunderland

rrice. oa
3600: 6
Odod
to
t 091:

.11.1
Great fears were entertained by the °Pißinot.
and crew, for the safety the Sovereign WA on
packet, from Itarnsgate, which left that Piace4oa
Saturday morning with above 100 Passenger-t- ,
board. As soon as they had passed Alarga-eCe
fog came on so exceedingly thick and tiel::‘,/t
that it was impossible to distinguish anY °fin
at half a cable's length, and the lead i'va- it
ce
cleared up, it having
constant use until one o'clock, wile," font
drowned,d
Liverp oo
hours. The packet did not arrive in Lb°
until after six o'clock.
Twenty poor Irish harvest rpturnitl
people) fro
lasted 010 r. arm c'iii°ver
home.. in the Si. George steam-Packet'
ie
-danger of
ping a heavy sea : one time such wu-, thetreat
verity of the storm, that the vessel wall 'n
Liverpool,
ne:vni‘e:rooltousi
ta. washed‘cee
koverheard,;it' 114.:

BI RTHS. laari
On Sunday, the 19th inst., at Blackheath, gent, the
11 -„Lumley, Etuj. (late bliss Ilaniet Bilis), of a scalSswortht
On Sunday, the 19th inst.,_ Mrs. Samuel 111 r.
Porto-Bello, near Wakefield, Yorkshire, of a tlaufPrfe,
W
On Thursday, the 9th inst., at Brixton-hill,„,ba
James Elderton, of a son, being her eleventh chltu•
On the 3d ult., at Florence, the lady of John Group,'
of Auchenatnes, of a son.

On Thursday,
MA R RIE D. 00,
h o ral
Esq., of Ke el.strect, Russell-square, to SePivol ,
daughter of Holland Watson, Esq-s of Congletou,
the 10th hist at Astbury, Jock: fau
county of Chester.

G rOe ant Itthues sle
DIED.
On Saturday, the 18th lust , at Pentontme, as.--
,„, of
...., —.41 31, ,14116
the wife of Mr. Massey, of the Poultry.
.. the la'
Oa Satarday, the 18th inst.,
son of Mr. Thomas Godwin,
On the 17th inst., at 31ilton, Kent, Francis Chaff lit.lsitrienestt:,l;eiLitß.l' Ramsgate,
eldV4i3ll.itun WWI -P""
fent son of Edward Cohen, Esq., of Islington,alier.,u_ 0000'
HaMpshire, oS
On Sunday.evening, at Shirley-haute,
years, the Rev. Sir Charles Rich, Bart.
0101°1(4
. ,
Printed and Published for the PROPRIETOIOII 14 0.
OFE)ICE, No. 112, Strand, by J. B. Coes.rat
of
Glitiiistefarltaerne.'s,,lll4ttot.a t a
~,,..,