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4200 | 4200 | These findings confirm that @GENE$ variants influence colorectal @DISEASE$ independent of aspirin intake and suggest that they may have clinical value in secondary prevention programs for patients diagnosed with colorectal adenoma. | [
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4201 | 4201 | These data support the hypothesis that the @DISEASE$ observed in the blood vessels of smokers is related to reduced NO bioactivity but indicate that @GENE$ genotype does not influence significantly the level of plasma NO(x) or the risk of IHD in this population sample of middle-aged British men. | [
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] |
4202 | 4202 | Our findings argue against an important predisposing effect of the MC1R and @GENE$ genes for @DISEASE$. | [
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] |
4203 | 4203 | The incidence of @DISEASE$ in the @GENE$ domains of EGFR was very low and the increased gene copy number of EGFR did not significantly influence survival. | [
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] |
4204 | 4204 | Genetic variation in @GENE$ does not have a major effect on @DISEASE$ susceptibility in the UK population. | [
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] |
4205 | 4205 | The authors believe that @GENE$ VV genotype is associated with the development of NTDs and @DISEASE$. | [
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] |
4206 | 4206 | Our data indicate that @GENE$ gene polymorphism as opposed to the other ethnic groups does not appear to be relevant in @DISEASE$ susceptibility in Mexican patients and that the distribution of the different alleles depend on the frequency of HLA alleles associated with them. | [
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] |
4207 | 4207 | SNP rs3744700 of CXCL16 gene is independently associated with the development of CAD in Chinese Han population, and GG homozygote which is associated with increased expression of @GENE$ may have a promoting effect on @DISEASE$. | [
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] |
4208 | 4208 | The @GENE$ of MC1R variants on risk of @DISEASE$ was mediated largely through the action of three common alleles, Arg151Cys, Arg160Trp, and Asp294His, that have previously been associated with red hair, fair skin, and skin sensitivity to ultraviolet light. | [
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] |
4209 | 4209 | @GENE$ genetic variations are associated with risk factors, severity, type and prognosis of @DISEASE$ and oxidative stress. | [
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] |
4210 | 4210 | Our results replicate previous findings and implicate the @GENE$ -38C/T SNP in the regulation of @DISEASE$ in West Africans. | [
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] |
4211 | 4211 | The distribution of @GENE$ exon 1 A(49)G genotype, phenotype and allele frequencies did not differ between patients with @DISEASE$ and healthy subjects. | [
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] |
4212 | 4212 | This study suggests that the Asn allele in the SHBG gene may be related to a reduced risk of @DISEASE$ among postmenopausal women by increasing their blood @GENE$ levels. | [
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] |
4213 | 4213 | Our findings show that the @GENE$/NPRA system significantly contributes to ventricular remodeling in human @DISEASE$. | [
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] |
4214 | 4214 | These observations suggest that the 4G/5G polymorphism in @GENE$ may explain some of the increased risk and earlier mean age of onset of @DISEASE$ due to a positive family history. | [
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] |
4215 | 4215 | These results suggest that the tested functional variation of @GENE$, IL-8, IL-1alpha, and MCP-1 genes do not confer a relevant role in the susceptibility or severity of @DISEASE$ in the Spanish population. | [
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] |
4216 | 4216 | Thus, neither HLA DMA nor @GENE$ was associated with @DISEASE$ in this population, and not all shared-epitope-bearing haplotypes had the same DMB allele distribution. | [
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] |
4217 | 4217 | These data indicate that the effect of @GENE$ gene variation is attributable to the 5A/6A polymorphism and that individuals carrying the 6A/6A genotype may be predisposed to developing atherosclerotic @DISEASE$ with significant stenosis, whereas those carrying the 5A allele may be predisposed to developing unstable plaques. | [
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] |
4218 | 4218 | @GENE$ gene may be involved in the development of @DISEASE$ by moderating the impact of depressogenic social influences. | [
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] |
4219 | 4219 | @GENE$ variation, although strongly associated with A1C, does not seem to be involved in @DISEASE$ glucose control. | [
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] |
4220 | 4220 | the rs11200638 variant in the @GENE$ gene is strongly associated with @DISEASE$ in the Japanese population. | [
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] |
4221 | 4221 | Our findings suggest that the @GENE$ 2677G>T and 3435C>T polymorphisms can be used for predicting treatment response to etoposide-cisplatin chemotherapy in @DISEASE$ patients. | [
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] |
4222 | 4222 | The @GENE$ N34S mutation appears not to predispose Hispanic or non-Hispanic white people from the USA to the development of @DISEASE$. | [
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] |
4223 | 4223 | In conclusion, the frequency of the 112/121 at-risk haplotype of @GENE$ is low among Scandinavians and we were unable to demonstrate significant associations between the CAPN10 variants and @DISEASE$, insulin resistance, or impaired insulin secretion. | [
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] |
4224 | 4224 | We found that patients with the @GENE$ GA/AA genotype were more likely to have advanced @DISEASE$ scores | [
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] |
4225 | 4225 | The polymorphisms of @GENE$ and IL-6 -174G/C appear to be associated with @DISEASE$, and the polymorphisms of IL-1 +3953 and IL-10 promoter gene are not associated with PBC in a Chinese population. | [
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] |
4226 | 4226 | In contrast to traditional coronary risk factors, the @GENE$ M/L @DISEASE$ can be considered predictive of protection against CAD. | [
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] |
4227 | 4227 | It is unlikely that @GENE$ c.1-34T>C has a role in @DISEASE$ etiology, overall or in combination with established non-genetic breast cancer risk factors. | [
"1"
] |
4228 | 4228 | Differences in physiological levels of @GENE$ expression did not modify HIV-1 @DISEASE$ in vitro, nor did MDR1 alleles and haplotypes significantly influence either permissiveness to infection in vitro or disease progression in vivo before the initiation of treatment. | [
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] |
4229 | 4229 | In this sample, @GENE$ AA, associated with decreased production of myeloperoxidase, was found to be a risk factor for @DISEASE$. | [
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] |
4230 | 4230 | Our findings indicate that the @GENE$ @DISEASE$ polymorphism may not be associated with risk of lung cancer in the Chinese population. | [
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] |
4231 | 4231 | The results suggest that the @GENE$ gene may not be involved in the etiology and @DISEASE$ of schizophrenia in the Chinese population. | [
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] |
4232 | 4232 | These results suggest that unlike for other cancer types, the @GENE$ Ser326Cys polymorphism is not a major genetic risk factor for @DISEASE$. | [
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] |
4233 | 4233 | Our findings suggest that the @GENE$-repeat polymorphism in the promoter region of the NEP gene or some other unknown polymorphisms, which are in a linkage disequilibrium, confer a susceptibility to late-onset @DISEASE$. | [
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] |
4234 | 4234 | The findings of this large study strongly support the notion that @GENE$ mutations characterize a subgroup of bladder cancers with good prognosis; patients with @DISEASE$ TaG1 tumors have a higher risk of recurrence; and the F386L variant is selectively associated with low-grade tumors. | [
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] |
4235 | 4235 | These studies support that @GENE$ mutations are not a common cause of CAD in white people and argue strongly against a role for the MEF2A 21-bp @DISEASE$ in autosomal dominant CAD. | [
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] |
4236 | 4236 | These results suggest that @GENE$ variants may act through insulin secretion to increase the risk of @DISEASE$. | [
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] |
4237 | 4237 | The data obtained in the present study strengthen the evidence of an association of the @GENE$ T8590C polymorphism with @DISEASE$ pressure levels and hypertension prevalence. | [
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] |
4238 | 4238 | We observed that @GENE$ G395A polymorphism was associated with @DISEASE$ pressure and KLOTHO C1818T polymorphism was associated with glucose metabolism in Korean women. | [
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] |
4239 | 4239 | Our results provide no evidence for an association between @DISEASE$ risk and @GENE$ T/C polymorphism. | [
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] |
4240 | 4240 | These results demonstrate the association of a new polymorphism of @GENE$ (I232T) with susceptibility to @DISEASE$ in the Japanese. | [
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] |
4241 | 4241 | These data suggest that the gene for the proinflammatory chemokine @GENE$ is involved in susceptibility to @DISEASE$ during upper urinary tract infection in children with or without vesicoureteral reflux. | [
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] |
4242 | 4242 | In conclusion, the hypofibrinolytic genotypes 4G/4G and A/A at positions -675 and -844 of the PAI-1 gene are associated with the occurrence of mild @DISEASE$ independently of thrombophilic mutations of the factor V, @GENE$, and MTHFR genes. | [
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] |
4243 | 4243 | Results from this first study of MPO genotypes and breast cancer risk indicate that @GENE$ variants, related to reduced generation of ROS, are associated with decreased breast cancer risk, and emphasize the importance of fruit and vegetable consumption in reduction of @DISEASE$ risk. | [
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] |
4244 | 4244 | Our data suggest that @GENE$ @DISEASE$ is a typical feature of certain subtypes of ovarian carcinoma. | [
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] |
4245 | 4245 | This @DISEASE$ is consistent with the suggestion that the K variant of @GENE$ has an important role in disease progression in AD, and this may have implications for treatment. | [
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] |
4246 | 4246 | Cerebellar @DISEASE$ consistent with the @GENE$ may be relatively common in patients with juvenile NPHP without classic symptoms of JS. | [
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] |
4247 | 4247 | These results do not support the hypothesis that TGFB1 L10P genotypes modify the risk of @DISEASE$ in BRCA1 or @GENE$ mutation carriers. | [
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] |
4248 | 4248 | These results suggest that a Trp64Arg @DISEASE$ in the @GENE$-adrenergic receptor gene is not associated with hypertension in Japanese NIDDM patients without nephropathy. | [
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] |
4249 | 4249 | Our study suggests a potential role of the @GENE$ polymorphisms and their haplotypes in susceptibility to @DISEASE$ and disease severity. | [
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] |
4250 | 4250 | Our data suggest that the association between the @GENE$ -238 polymorphism and @DISEASE$ could play a major role in disease susceptibility. | [
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] |
4251 | 4251 | The results support a possible role of the @GENE$ gene in @DISEASE$. | [
"1"
] |
4252 | 4252 | Polymorphisms in the oxidative stress-related genes (@GENE$, GSTM1, GSTT1, MPO, MnSOD) do not seem to be risk factors for @DISEASE$. | [
"1"
] |
4253 | 4253 | All these results suggest that the Q(296) @DISEASE$ in @GENE$ gene was closely related to CHD, and the identification of new mutations in the CETP gene will afford the opportunity to investigate the relationship between CETP gene and CHD. | [
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] |
4254 | 4254 | Our findings suggest that the @GENE$/@DISEASE$ genotype is associated with hemostasis balance disturbances reflecting hypercoagulability and endothelial damage in patients with untreated hypertension. | [
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] |
4255 | 4255 | The @GENE$ and CDSN genes are important @DISEASE$ susceptibility genes in Chinese patients with psoriasis vulgaris. | [
"0"
] |
4256 | 4256 | This suggests that both polymorphisms in the @GENE$ gene may be associated with lipid and lipoprotein @DISEASE$ in CHD in the Chinese. | [
"0"
] |
4257 | 4257 | This study suggests that common variation at the @GENE$ gene (and not just rare loss-of-function mutations) is associated with @DISEASE$ in girls and young women. | [
"0"
] |
4258 | 4258 | The SLC6A14 gene is an interesting novel candidate for @DISEASE$ because it encodes an @GENE$, which potentially regulates tryptophan availability for serotonin synthesis and thus possibly affects appetite control. | [
"0"
] |
4259 | 4259 | Serine at position 986 of @GENE$ may be an independent genetic predictor of angiographic @DISEASE$, previous MI, and cardiovascular mortality. | [
"0"
] |
4260 | 4260 | A population-attributable risk of approximately 50% for the Pro12Pro genotype indicates that testing for the Pro12Ala of the @GENE$ gene in addition to the already identified clinical risk factors may become a useful tool to further reduce the risk of PPARgamma agonist-induced @DISEASE$ and edema in patients with type 2 diabetes. | [
"0"
] |