baber/WOPTO huggingface dataset:
Patent AT-E211253-T1 (AT)
Inventor: DANIELLI FRANCO
IPC: G01B21/00
Filed: 1999-03-29
Granted: 2002-01-15
Abstract: Head for checking linear dimensions of parts in machine tools or measuring machines, with a casing, a movable arm-set including an arm carrying a feeler for contacting the part to be checked, a biasing device arranged between the casing and the movable arm-set, a detecting device for providing a signal depending on the position of the movable arm-set, and two constraining systems-between the casing and the movable arm-set-both totally with force closure under the action of the biasing device, that eliminate, in a univocal way, the six degrees of freedom of the movable arm-set, one of the two constraining systems featuring a structure with rotational symmetry.
Patent AT-E243178-T1 (AT)
Inventor: KINDLER KLAUS
IPC: C07C9/10
Filed: 1999-04-13
Granted: 2003-07-15
Abstract: A C4-hydrocarbon mixture essentially containing 1,3-butadiene, butenes, butanes and other C4-hydrocarbons is separated into at least 4 fractions,a) the fraction (a) essentially comprising 1,3-butadiene,b) the fraction (b) essentially comprising butenes,c) the fraction (c) essentially comprising butanes andd) one or more fractions (d) essentially comprising 1,3-butadiene and the other C4-hydrocarbons,by extractive distillation by means of N-methyl-2-pyrrolidinone or an aqueous solution of N-methyl-2-pyrrolidinone (NMP).
Patent AT-E307837-T1 (AT)
Inventor: MATIJEGA RONEY J
IPC: C08G18/32
Filed: 1999-04-20
Granted: 2005-11-15
Abstract: The present invention is a polyurethane foam comprising the reaction product of a first reactant comprised of a polyisocyanate having an average isocyanate functionality of at least 2 and a second reactant comprised of a low molecular weight compound that has at least two to, at most, three groups containing an active hydrogen and water, wherein the reaction product is formed essentially in the absence of a cross-linking polyol and the polyurethane foam is substantially rigid. The invention is also a method of forming the polyurethane foam by contacting the first and second reactant for a time and temperature sufficient to form the foam.
Patent AT-E277960-T1 (AT)
Inventor: TOMOTAKI YOSHIHISA
IPC: C09D163/00
Filed: 1999-04-28
Granted: 2004-10-15
Abstract: A curing agent for epoxy resin which comprises at least one selected from 1-aminopyrrolidine and its salt, as an effective component.
Patent AT-E322695-T1 (AT)
Inventor: YOON CHUL OH
IPC: G01R31/36
Filed: 1999-06-15
Granted: 2006-04-15
Abstract: Provided with a method of measuring battery capacity using parameters obtained from a voltage response signal of a current waveform or an impedance spectrum generated thereof where the method includes the steps of: measuring voltage response signals based on a current waveform applied to a primary or secondary battery; obtaining parameters of an equivalent circuit composed of model parameters such as resistors, capacitors and transmission lines either directly from voltage response or after its conversion to frequency dependent impedance; and determining the unknown battery capacity from the voltage response characteristics based on a correlation between the measured capacity and the model parameters, which correlation is previously determined by a real-time discharge method, thereby takes a shorter time than a real-time discharge method and delivering efficiency and reliability in determining model parameters of an equivalent circuit which are in close correlation with the charge/discharge condition of the battery.
Patent AT-E259428-T1 (AT)
Inventor: DRY RODNEY JAMES
IPC: C21B13/14
Filed: 1999-07-26
Granted: 2004-02-15
Abstract: A process for direct smelting a metalliferous feed material is disclosed. Char and fuel gas are produced by pre-treating coal with an oxygen-containing gas. The fuel gas is used to heat an oxygen-containing gas and/or to produce an oxygen-containing gas in an oxygen plant. Metalliferous feed material, char, and the oxygen-containing gas are injected into a direct smelting vessel, and the metalliferous feed material is smelted to molten metal in the direct smelting vessel using the char as a source of energy and as a reductant.
Patent AT-E380802-T1 (AT)
Inventor: JONES RAYMOND VINCENT H
IPC: B01J31/28
Filed: 1999-08-23
Granted: 2007-12-15
Abstract: A process for the preparation of 3-isochromanone which comprises contacting an o-xylene-alpha,alpha'-dihalide with carbon monoxide, in the presence of a catalyst and a hindered amine base in a liquid medium comprising water and a tertiary alcohol.
Patent AT-E234267-T1 (AT)
Inventor: TORR ASHLEY CARL
IPC: B60J1/00
Filed: 1999-11-12
Granted: 2003-03-15
Abstract: A high performance green glass composition containing at least 14.5% by weight Na2O, at least 10.5% by weight CaO, at least 0.5% by weight total iron (measured as Fe2O3) and is substantially magnesium-free, the glass thus produced having a ferrous value of at least 30% and a performance (light transmission minus Direct Solar Heat Transmission) of at least 28% at at least one thickness of 2.8 mm to 5 mm. The invention also relates to glasses made from such composition and to a laminated glass assembly in which two sheets of glass sandwich a polymeric material, at least one, preferably both, of the sheets of glass having such a composition.
Patent AT-E290258-T1 (AT)
Inventor: BISHOP PETER G
IPC: H01R12/71
Filed: 1999-10-27
Granted: 2005-03-15
Abstract: A thin profile electrical connector includes an insulating body member having a longitudinally extending leg defined between opposite ends. A plurality of adjacently disposed and spaced apart connector elements are mounted on the longitudinal leg, for example within recesses or grooves defined transversely to the longitudinal leg. Each connector element includes a closed end and an open end defined by extending arms. The closed end wraps around the longitudinal leg at each connector position. Each connector element includes outwardly facing contact surfaces defined on each of the extending arms for mating contact with respective pads of separate facing circuit boards.
Patent AT-E281475-T1 (AT)
Inventor: YEUNG DOMINIC WAI KWING
IPC: C08F2/32
Filed: 1999-12-09
Granted: 2004-11-15
Abstract: A polymer produced by polymerizing via water-in-oil emulsion polymerization one or more water soluble monomers with one or more polyalkoxylated monomers wherein said one or more polyalkoxylated monomers contains at least 25 alkylene oxide units and wherein said product demonstrates thermothickening properties, its method of manufacture and use thereof is disclosed.
Patent DE-02709944-T1 (DE)
Title: Jacke mit verstellbarer kapuze
Inventor: FAYLE WALKER
IPC: A41D3/00
Filed: 2002-01-24
Abstract: Eine Kopfbedeckung und eine Gesichtsöffnung aufweisende Kapuze mit einer verstellbaren Kordelzug-Anordnung für das gleichzeitige Zusammenziehen der Kopfbedeckung in Umfangsrichtung bzw. der Gesichtsöffnung in vertikaler Richtung im Schläfenbereich, bei der die Kordelzug-Anordnung einen oder mehrere, die Kopfbedeckung im Oberkopfbereich umlaufende Kordelabschnitte umfasst, die mit einem jeweils seitlich an der Gesichtsöffnung im Schläfenbereich befindlichen linken bzw. rechten Kordelabschnitt verbunden sind, so dass:  (a) durch das manuelle Zusammenziehen des den Oberkopfbereich umlaufenden Kordelabschnitts die Kordelabschnitte in den Schläfenbereichen zusammengezogen werden; oder  (b) durch das manuelle Zusammenziehen des entweder im linken oder rechten Schläfenbereich befindlichen Kordelabschnittes ein den Oberkopfbereich umlaufender Kordelabschnitt zusammengezogen wird.
Patent DE-02751521-T1 (DE)
Title: Kaugummi- und süsswarenzusammensetzung zur entfernung von verunreinigungen und verfahren zur herstellung und verwendung derselben
Inventor: LUO JOHN
IPC: A23G3/36
Filed: 2002-08-02
Abstract: Flecken
entfernende Kaugummizusammensetzung mit einem Kern und einer fakultativen
Hülle mit
zumindest einer Schicht, wobei zumindest entweder der Kern oder
die Hülle
eine Flecken entfernend wirkende Menge an zumindest einem Flecken
entfernenden Mittel aufweist, das ausgewählt ist aus der Gruppe bestehend aus
anionischen und nicht-ionischen grenzflächenaktiven Stoffen, und das
Flecken entfernende Mittel auf eine Weise vorliegt, die eine Freisetzung
einer wirksamen Menge des Flecken entfernenden Mittels aus der Zusammensetzung ermöglicht.
Patent DE-04006876-T1 (DE)
Inventor: NEE HAN H
IPC: C22C9/05
Filed: 1999-06-14
Abstract: A copper-based silver alloy thin film is provided for the highly reflective (219) or semi-reflective (215) layer of optical discs. Alloy additions include cadmium, magnesium, aluminium, and nickel. These alloys have moderate to high reflectivity and reasonable corrosion resistance in the ambient environment.
Patent DE-08290636-T1 (DE)
Inventor: DAZIN GUILLAUME
IPC: G05D19/00
Filed: 2008-06-27
Abstract: The system has a variable flow hydraulic pump (8) driven by a motor feeding hydraulic fluid to a vibrator or a vibrating system. The vibrating system comprises eccentric weights driven in rotation by one hydraulic motor receiving fluid. An adaption unit is provided for continuous adaptation of rotation speed of a motor (9) of the hydraulic unit (7) in relation to the energy actually consumed by the vibrator (1). The vibrator is provided with a vibration frequency sensor, where the motor of the hydraulic group is a heat engine equipped with a device to measure a load rate.
Patent DE-80341-T1 (DE)
IPC: A61K9/22
Filed: 1982-11-19
Abstract: A pharmaceutical oral controlled release multiple-units formulation in which individual units comprise cross-sectionally substantially homogeneous cores containing particles of a sparingly soluble active substance, the cores being coated with a coating which is substantially resistant to gastric conditions, but which is erodable under the conditions prevailing in the small intestine, in particular an enteric coating which is substantially insoluble at a pH below 7 such as Eudragit<sup>0</sup> S (an anionic polymerisate of methacrylic acid and methacrylic acid methyl ester), is prepared by a process comprising comminuting an active substance together with a substance which is readily soluble in intestinal fluids such as an anionic detergent to obtain particles containing the active substance in intimate admixture with the readily soluble substance, combining the resulting particles into cross-sectionally substantially homogeneous cores together with components which accelerate the disintegration of the cores in intestinal fluids such as talc and sucrose, coating the individual cores with the coating, and combining a multiplicity of the coated cores into a capsule or tablet formulation.As the coating is erodable in an alkaline environment only, the active substance is not released until the units arrive at a section ofthe small intestine with an alkaline pH. Thus, a reduction and delay of the peak plasma concentration is obtained without affecting the extent of drug availability.A coating of the above-defined type may also be used when the active substance is a substance which exerts an irritating effect on the gastric mucosa and/or is unstable in an acidic environment.
Patent DE-197409-T1 (DE)
IPC: A61K31/545
Filed: 1986-03-24
Abstract: 7-Aminothiazolyl-oximino- acetamido-3-cephems of formula (I) and their salts and hydrates are new. - In formula (I) R1 = H or protecting gp.; R2, R3 = H, Me or opt. protected COOH; or R2 + R3 = O; R4, R5 = H; or R4 + R5 = O; R6 = H or protecting gp.; a, b, c = 0 or 1; the broken bond is an opt. double bond, and the wavy line indicates a bond to a syn- or anti-isomer; X = H, OH, 6,7-(COOMe)2-2-naphthyl, 3,4-(OH)2-1-naphthyl or a gp. of formula (II); where R7 = H, Cl, COOH, Me, iPr, OH, OMe or OCOMe; R8, R9 = H, Cl, Me, OH, OMe, OEt, OCOMe, OCOCH2Cl, butanoyloxy, methanesulphonyloxy, toluene-p-sulphonyloxy, NH2, MeCONH, PhCH2OCONH, NO2 or MeSO2; or R8 + R9 = OCH2CH2O or OCOO; R10 = H, OH, OCOMe, Me, OMe, NO2 or OCOCH2Cl; Z = C or N; d = 0 or 1; Y = halogen, OCOMe.
Patent DE-216240-T1 (DE)
IPC: B67D7/32
Filed: 1986-09-09
Abstract: This invention adds a fuel pressure sensitive piston (22) at a location adjacent to the automatic shut off mechanism (14) of a fuel dispensing nozzle, extending a lever (36) responsive to the reciprocal movements of the piston (22) for either biasing against the diaphragm (15) of the shut off mechanism (14), to raise it and disengage its associated latch mechanism (17) for release of the dispenser handle (8) and closure of the nozzle poppet valve (6), as when there is no fuel being delivered from the pump, or in the alternative, shifting said lever (36) to disengage the diaphragm (15), as when fuel pressure from the pump at the inlet (3) of the nozzle (1) forces the piston (22) in an opposite direction, thereby releasing its contact with said diaphragm (15), and allowing the automatic shut off mechanism (15) to routinely function.
Patent DE-200352-T1 (DE)
IPC: G06F19/00
Filed: 1986-03-25
Abstract: A computer control system, especially a flight control computer system, comprises a series of computer modules operating in parallel and asynchronously to carry out respective parts of an overall control algorithm for a series of items to be controlled, each computer module having a data transmission port connected via a broadcast line to a respective input port of each other computer module so that communication between modules is achieved by any of the modules broadcasting asynchronous data messages onto its broadcast line for the messages to be received by any other modules which require them.
Patent DE-576568-T1 (DE)
Inventor: BJORGE PER H
IPC: G06K15/12
Filed: 1992-03-03
Abstract: A trapping technique which accepts a Postscript or other page description language (PDL) file and outputs a file in PDL format having the correct traps. The input page is first divided into sub-portions, or tiles, and the tiles are individually processed by evaluating the input file in a corresponding clipping window. Each tile is then analyzed to determine where edges exist. The edge data is fed to an edge converter which produces a list of color transitions consisting of the analytic description of each edge and the color information along the sides of the edge. The color transition information is fed to a trapping analyzer which generates trap vectors in accordance with a set of desired trapping rules. The trap vectors are then converted to PDL form. As a final step, the trap vectors are added to the original PDL file. The final trapped page may be printed on standard typesetters without the need for special trap generator hardware.
Patent DE-1123584-T1 (DE)
Inventor: OZLUTURK M
IPC: H04B1/7107
Filed: 1999-01-27
Abstract: An apparatus for code division multiple access (CDMA) wireless communication comprising a receiver configured to receive a CDMA signal that includes a desired traffic signal and a second signal, the desired traffic signal being spread with a desired traffic spreading code and the second signal being spread with a second spreading code; means for generating a second signal cancellation component including means for generating a second signal strength by despreading the CDMA signal based on the second spreading code; means for generating a second signal cancellation factor by selectively combining the second signal spreading code and the desired traffic spreading code; and means for combining the second signal strength and the second signal cancellation factor to generate the second signal cancellation component; means for generating a despread desired traffic signal by despreading the CDMA signal based on the desired traffic spreading code; and means for combining the despread desired traffic signal and the second signal cancellation component to cancel second signal noise from the despread desired traffic signal.
Patent ES-2282059-T1 (ES)
Inventor: PERILLON JEAN-LUC
IPC: D06N7/04
Filed: 2002-09-26
Abstract: A display support, designed to be printed, includes a coated fabric comprising a textile layer and two impregnation layers located on opposite surfaces of the textile layer. A coat of varnish, designed to be printed, is deposited on one of the impregnation layers. A pressure-sensitive adhesive layer capable of being repositioned, is deposited on the impregnation layer opposite the one receiving the coat of varnish. A protective layer arranged on the adhesive layer consists of a sheet with low adherence strength relative to the pressure-sensitive adhesive layer.
Patent ES-2239939-T1 (ES)
Inventor: CLERGET SERGYL
IPC: E05F15/14
Filed: 2004-11-30
Abstract: The device has a guide rail (4) for horizontally moving a carriage (3) between two ends of the rail using a chain (5). The chain is driven by two driving wheels placed at the ends of the rail, where one of the driving wheels is driven in rotation by a gear motor (2). The gear motor is cylindrical and has a longitudinal axis (XX) around which the driving wheel is rotated.
Patent CY-1108424-T1 (CY)
Inventor: MAERTENS GEERT
IPC: C12N15/09
Filed: 2008-10-16
Abstract: The present invention relates to a method for purifying a cysteine containing recombinantly expressed protein comprising at least 2, preferably 3 or 4 and even more preferably all of the following steps:  (a) sulphonation of a lysate from recombinant host cells or lysis of recombinant host cells in the presence of guanidinium chloride followed by a subsequent sulphonation of the cell lysate, (b) treatment with a zwitterionic detergent, preferably after removal of the cell debris, (c) purification of the sulphonated version of the recombinant protein or purification of the sulphonated version of the recombinant protein with subsequent removal of the zwitterionic detergent, with said purification being preferably chromatography, more preferably a Ni-IMAC chromatography with said recombinant protein being a His-tagged recombinant protein, (d) desulphonation of the sulphonated version of the recombinant protein, preferably with a molar excess of DTT, (e) storage in the presence of a molar excess of DTT.
Patent CY-1108756-T1 (CY)
Title: Μεθοδος για τον καθαρισμο διασερεϊνης
Inventor: MAGGI DOMENICO
IPC: C07C69/00
Filed: 2009-02-03
Abstract: Μέθοδος για την παρασκευή διασερεΐνης, όπου ακατέργαστη διασερεΐνη καθαρίζεται με κρυστάλλωση με ένα μίγμα διαλυτών που συνίσταται από οξεικό οξύ και οξεικό ανυδρίτη ή μόνο οξεικό ανυδρίτη, το δε διάλυμα προαιρετικά κατεργάζεται με αιθυλενο-διαμινοτετραοξεικό οξύ για να απομακρυνθούν οποιαδήποτε ίχνη χρωμίου.
Patent CY-1112168-T1 (CY)
Title: Συνθεσεις και μεθοδοι θεραπειας της αγγειογενεσης σε παθολογικες βλαβες
Inventor: ZARDI LUCIANO
IPC: C07K14/57
Filed: 2011-12-20
Abstract: Θεραπεία βλαβών παθολογικής αγγειογένεσης, και ιδιαίτερα όγκων, ρευματοειδούς αρθρίτιδας, διαβητικής αμφιβληστροειδοπάθειας, γεροντικού εκφυλισμού της ωχρής κηλίδας, κι αγγειωμάτων. Χρησιμοποιείται ένα σύζευγμα που αποτελείται από ένα μόριο που ασκεί βιοκτόνο ή κυτταροτοξική δράση σε κύτταρα-στόχους στις βλάβες κι ένα αντίσωμα που κατευθύνεται έναντι ενός συστατικού του εξωκυτταρικού πλέγματος που είναι παρόν σε τέτοιες βλάβες. Το αντίσωμα μπορεί να κατευθύνεται έναντι φιβρονεκτίνης ΕD-Β. Το βιοκτόνο ή κυτταροτοξικό μόριο μπορεί να είναι ιντερλευκίνη-2 (ΙL-2), δοξορουβικίνη, ιντερλευκίνη-12 (ΙL-12), ιντερφερόνη-γ (ΙFΝ-γ), Ογκονεκρωτικός Παράγοντας α (ΤΝFα) ή πρωτεΐνη Ιστικού Παράγοντα (που μπορεί να είναι κομμένη).
Patent CY-1114080-T1 (CY)
Title: Αντισωματα αντι-ρ-σελεκτινης
Inventor: GRAUS YVO
IPC: C07K16/28
Filed: 2013-05-16
Abstract: Αυτή εφεύρεση αναφέρεται σε αντισώματα αντι-Ρ-σελεκτίνης και, ειδικότερα, σε αντισώματα αντι-Ρ-σελεκτίνης και παραλλαγές αυτών που περιέχουν ένα Fc τμήμα ανθρώπινης προέλευσης και δεν δεσμεύουν τον παράγοντα C1q συμπληρώματος. Αυτά τα αντισώματα έχουν νέες και εφευρετικές ιδιότητες που ωφελούν ένα ασθενή που πάσχει από κρίσιμη ισχαιμία των άκρων ή περιφερική αρτηριακή αποφρακτική νόσο (CLI /PAOD).
Patent CY-1115030-T1 (CY)
Title: Διειδικα αντι-vegf/αντι-ang-2 αντισωματα
Inventor: BAEHNER MONIKA
IPC: C07K16/46
Filed: 2014-04-15
Abstract: Η παρούσα εφεύρεση αφορά σε διειδικά αντισώματα κατά του ανθρώπινου VEGF και κατά της ανθρώπινης ANG-2, σε μεθόδους για την παραγωγή τους, σε φαρμακευτικές συνθέσεις που περιέχουν τα εν λόγω αντισώματα και σε χρήσεις αυτών.
Patent CY-1116425-T1 (CY)
Title: 1'-υποκατεστημενα αναλογα καρβα-νουκλεοζιδιων για αντiiϊκη αγωγη
Inventor: BUTLER THOMAS
IPC: A61K31/395
Filed: 2015-05-11
Abstract: Παρέχονται ιμιδαζολ[1,5-f][1,2,4]τριαζινυλ-, ιμιδαζολ[1,2,4]τριαζινυλ-, και [1,2,4]τριαζολ[4,3-f][1,2,4]τριαζινυλ-νουκλεοζίδια του χημικού τύπου I, φωσφορικά νουκλεοζιδίων και προφάρμακα εξ' αυτών. Οι ενώσεις, συνθέσεις και μέθοδοι που παρέχονται είναι χρήσιμες για την αγωγή των λοιμώξεων από ιό των Flaviviridae, ειδικότερα δε των λοιμώξεων της ηπατίτιδας C. Όπου το Χ-1 ή Χ-2 είναι ανεξαρτήτως C-R10 ή Ν και όπου ένα τουλάχιστον εκ των Χ-1 και Χ-2 είναι Ν.
Patent CY-1117089-T1 (CY)
Title: ΣΥΣΤΗΜΑ ΕΓΧΥΣΕΩΣ ΠΟΛΤΟΥ ΜΙΚΡΟΚΟΝΙΟΠΟΙΗΜΕΝΟΥ CaCΟ3 ΓΙΑ ΤΗΝ ΕΠΑΝΑΜΕΤΑΛΛΙΚΟΠΟΙΗΣΗ ΑΦΑΛΑΤΩΜΕΝΟΥ ΚΑΙ ΓΛΥΚΟΥ ΥΔΑΤΟΣ
Inventor: SKOVBY MICHAEL
IPC: C02F1/68
Filed: 2015-12-30
Abstract: Η παρούσα εφεύρεση αφορά μία μέθοδο επεξεργασίας ύδατος και τη χρήση ανθρακικού ασβεστίου σε μία τέτοια μέθοδο. Ιδιαίτερα, η παρούσα εφεύρεση αφορά μία μέθοδο επαναμεταλλικοποιήσεως ύδατος που περιλαμβάνει τα βήματα παροχής ύδατος τροφοδοσίας, και εγχύσεως αερίου διοξειδίου του άνθρακα και ενός πολτού εντός του ύδατος τροφοδοσίας, όπου ο πολτός περιλαμβάνει μικροκονιοποιημένο ανθρακικό ασβέστιο.
Patent CY-1118911-T1 (CY)
Title: Πολυ-στρωματικη χαρτοπετσετα
Inventor: HARPER FRANK D
IPC: D21H27/30
Filed: 2017-05-29
Abstract: Πολυ-στρωματική απορροφητική πετσέτα που γίνεται από ίνα κατασκευής χάρτου που περιλαμβάνει τουλάχιστον ένα πρώτο στρώμα και ένα δεύτερο στρώμα συνδεδεμένα μαζί, η δε πετσέτα έχει βασικό βάρος μεγαλύτερο από 30 λίβρες ανά 3000 πόδια2 δεσμίδα (48,8 gsm) και λιγότερο από 50 λίβρες ανά 3000 πόδια2 δεσμίδα (81,4 gsm), όπου τα στρώματα επιλέγονται και προσκολλώνται μαζί έτσι ώστε η πετσέτα τυπικά δεικνύει (i) GM TEA, χλστ.-γραμ./χλστ.2 μεγαλύτερο από [0,00125 (GM Δραστικότητα, g/3") - 0,75] και (ii) GM Συντελεστή Εφελκυσμού, γραμ./ίντσα/%, μικρότερο από [0,0083 (GM Αντοχή Εφελκυσμού, γραμ./3") + 15,4] {(i) GM TEA, χλστ. γραμ./χλστ.2, μεγαλύτερο από [0,00952 (GM Ελαστικότητα, γραμ./εκ.) - 0,75] και (ii) GM Συντελεστή Εφελκυσμού, γραμ./εκ./%, μικρότερο από [0,0249 (GM Αντοχή Εφελκυσμού, γραμ./εκ.) + 6,06}.
Patent CY-1119023-T1 (CY)
Title: Ενα χιμαιρικο πολυπεπτιδιο λεπτινης φωκιας - ανθρωπου με αυξημενη διαλυτοτητα
Inventor: ERICKSON MARY
IPC: C07K14/575
Filed: 2017-06-28
Abstract: Η αποκάλυψη παρέχει χιμαιρικά πολυπεπτίδια και μόρια πυρηνικών οξέων εγκωδικεύοντας χιμαιρικά πολυπεπτίδια. Επίσης παρέχονται φαρμακευτικές συνθέσεις και μέθοδοι αγωγής για παθήσεις και διαταραχές συμπεριλαμβάνοντας λιποδυστροφία, δυσλιπιδαιμία, υπερλιπιδαιμία, υπερβάρος, παχυσαρκία, υποθαλαμική αμηνόρροια, νόσο του Αλτσχάιμερ, ανεπάρκεια λεπτίνης, πάθηση λιπαρού ήπατος ή διαβήτη (συμπεριλαμβάνοντας τύπο I και τύπο II). Επιπρόσθετες παθήσεις και διαταραχές οι οποίες μπορούν να υποβληθούν σε αγωγή με τις ενώσεις και μεθόδους που περιγράφονται εις το παρόν συμπεριλαμβάνουν μη-αλκοολική στεατοηπατίτιδα (NASH) και μη-αλκοολική πάθηση λιπαρού ήπατος (NAFLD), μεταβολικό σύνδρομο Χ και Νόσο του Χάντινγκτον.
Patent CY-1119850-T1 (CY)
Title: Χρηση της μετφορμινης σε συνδυασμο με ενεργοποιητη γλυκοκινασης και συνθεσεων που περιλαμβανουν μετφορμινη και ενεργοποιητη γλυκοκινασης
Inventor: MJALLI ADNAN M M
IPC: A61P3/10
Filed: 2018-01-04
Abstract: Η παρούσα εφεύρεση προσφέρει τις χρήσεις ενεργοποιητή γλυκοκινάσης σε συνδυασμό με μετφορμίνη. Οι χρήσεις περιλαμβάνουν θεραπεία του διαβήτη τύπου 2, μείωση της γλυκόζης αίματος, βελτίωση της ευαισθησίας στην ινσουλίνη, ενίσχυση της φωσφορυλίωσης της γλυκόζης και βελτίωση της θεραπευτικής αποτελεσματικότητας της μετφορμίνης. Η εφεύρεση προσφέρει επίσης φαρμακευτικές συνθέσεις που περιλαμβάνουν ενεργοποιητή ΓΚ και μετφορμίνη. Η εφεύρεση προσφέρει επίσης άλας που έχει σχηματιστεί μεταξύ μετφορμίνης και ενεργοποιητή ΓΚ.