baber/WOPTO huggingface dataset:
Patent NZ-584893-A (NZ)
Title: PORCINE DC-SIGN, ICAM-3 AND LSECtin AND USES THEREOF
Inventor: HUANG YAOWEI
IPC: C07K16/18
Filed: 2008-10-29
Abstract: A fusion protein that comprises a porcine DC-SIGN protein linked to a porcine LSECTin protein. Also disclosed are cells that comprise a nucleotide for the expression of the fusion protein and antibodies directed against pDC-SIGN (SEQ ID NO: 2).
Patent NZ-588648-A (NZ)
Title: Suture line administration technique using botulinum toxins
Inventor: BLUMENFELD ANDREW M
IPC: A61K38/48
Filed: 2009-03-31
Abstract: Provided is the use of a botulinum toxin in the manufacture of a medicament for treating a patient suffering from a headache, wherein the medicament is to be used in a method comprising the step of administering the botulinum toxin to a nerve located within 1.5 cm of at least one suture line of the patient's skull, wherein the suture line is selected from the group consisting of frontal suture, squamous suture, occipitomastoid suture, coronal suture, lambdoid suture and sagittal suture, wherein the administration alleviates at least one symptom of the headache, thereby treating the patient suffering from the headache
Patent NZ-589413-A (NZ)
Title: INHIBITORS OF IKK-beta SERINE-THREONINE PROTEIN KINASE
Inventor: MOFFAT DAVID FESTUS CHARLES
IPC: A61P25/28
Filed: 2008-04-23
Abstract: Disclosed herein is a compound of: · Cyclopentyl (2S,4E)-2-amino-5-{ 3-[4-carbamoyl-5 (carbamoylamino )-2-thienyl]phenyl} pent-4-enoate; · Cyclopentyl 5-{ 3-[4-carbamoyl-5-(carbamoylamino)-2-thienyl] phenyl} -L-norvalinate; · Cyclopentyl (2S,4E)-2-amino-5-{ 3-[4-carbamoyl-5-( carbamoylamino )-2-thienyl]-5-methylphenyl} pent-4-enoate; · Cyclopentyl (2S,4E)-2-amino-5-{ 5-[4-carbamoyl-5-( carbamoylamino )-2-thienyl]-2-methYlphenyl} pent-4-enoate; · Cyclopentyl O-{ 3-[4-carbamoyl-5-(carbamoylamino)-2-thienyl]phenyl} -L-homoserinate; · Cyclopentyl N-{ 3-[4-carbamoyl-5-(carbamoylamino)-2-thienyl]benzyl} -L-alaninate; · tert-Butyl N-{ 3-[4-carbamoyl-5-( carbamoylamino )-2-thienyl]benzyl} -L-alaninate; · (2S,4E)-2-ami no-5-{ 3-[ 4-carbamoyl-5-(carbamoylamino)-2-thienyl]phenyl} pent -4-enoic acid; · 5-{ 3-[ 4-carbamoyl-5-( carbamoylamino )-2-thienyl]phenyl} -L-norvaline; · (2S,4E)-2-am ino-5-{ 3-[4-carbamoyl-5-(carbamoylamino)-2-thienyl]-5-methylphenyl} pent-4-enoic acid; · (2S,4E)-2-amino-5-{ 5-[4-carbamoyl-5-(carbamoylamino)-2-thienyl]-2-methylphenyl} pent-4-enoic acid; · O-{ 3-[4-carbamoyl-5-(carbamoylamino)-2-thienyl]phenyl} -L-homoserine; · N-{ 3-[4-carbamoyl-5-(carbamoylamino)-2-thienyl]benzyl} -L-alanine; and pharmaceutically acceptable salts thereof, processes for their preparation, pharmaceutical compositions comprising said compounds and uses thereof. Said compounds are useful as inhibitors of IKK-â serine-Theronine protein kinase as such are useful in the treatment of proliferative disease states such as hepatocellular cancer or cancer, bowel cancer, ovarian cancer, head and neck and cervical squamous cancers, gastric or lung cancers, anaplastic oligodendrogliomas, glioblastoma multiforme or medulloblastomas; autoimmune and inflammatory diseases such as rheumatoid arthritis, psoriasis, inflammatory bowel disease, Crohn's disease, ulcerative colitis, chronic obstructive pulmonary disease, asthma, multiple sclerosis, diabetes, atopic dermatitis, graft versus host disease, or systemic lupus erythematosus.
Patent NZ-589535-A (NZ)
Title: Deflectable removable spacer for use when adhesively attaching articles to surfaces
Inventor: THOMPSON CRAIG D
IPC: C09J7/10
Filed: 2009-05-06
Abstract: Methods and assemblies for mounting an article (7) to a surface (111) by a double-faced adhesive (100) are disclosed. At least one spacer (50) is used that is deflectable upon the application of sufficient force. When in a first, undeflected condition, the spacer provides sufficient space between the mounting surface and the double-faced adhesive such that the double-faced adhesive does not contact the mounting surface, thus the position of the article can be adjusted. When in a second, deflected condition, the spacer allows the double-faced adhesive to contact the mounting surface such that a bond can be established between the double-faced adhesive and the mounting surface. In the second, deflected condition, portions (56) of the spacer are deflected such that the spacer is removable from the article.
Patent NZ-592231-A (NZ)
Title: Methods to generate bacteriophage resistant bacterial strains and produce bacteriophage CRISPR loci phage mutants
Inventor: BARRANGOU RODOLPHE
IPC: A23K20/195
Filed: 2008-02-29
Abstract: Discloses a method for generating CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat) escape phage mutants comprising: (i) obtaining: at least one parent phage and a phage-resistant bacterial strain comprising at least one CRISPR locus, where the CRISPR locus comprises a bacteriophage nucleic acid sequence that is at least about 95% identical to at least one proto-spacer sequence in the genome of said at least one parent phage; (ii) exposing at least one parent phage to said phage-resistant bacterial strain, under conditions such that at least one phage variant is produced; and (iii) selecting at least one phage variant, where at least one phage variant exhibits the ability to infect the said phage-resistant bacterial strain and is a CRISPR-escape phage mutant Further discloses a method for generating a phage-resistant bacterial strain of (i) with a modified CRISPR locus comprising at least a portion of the CRISPR locus and at least one further nucleic acid sequence. Methods of screening for said phage-resistant bacterial strain or the variant phages capable of infecting the phage-resistant bacterial strain are disclosed. The bacteriophage is selected from the group of virus families consisting of: Corticoviridae, Cystoviridae, Inoviridae, Leviviridae, Microviridae, Myoviridae, Podoviridae, Siphoviridae, and Tectiviridae. Suitable phage-resistant bacterial strains that may be used for the methods are disclosed. The invention finds application in provision of methods to generate and screen for useful phage-resistant bacterial strains for use in e.g. dairy manufacturing processes. The invention also finds application in provision of methods to generate useful phage-resistant bacterial strains for use as biocontrol agents in e.g. dairy manufacturing processes.
Patent NZ-597182-A (NZ)
Title: Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response
Inventor: LONG DEBORAH
IPC: A61P31/22
Filed: 2010-05-24
Abstract: Disclosed is a vaccine formulation comprising a pharmaceutically acceptable carrier and an HSV-2 gD2 polypeptide, wherein the gD2 polypeptide has an internal deletion of all or part of a transmembrane domain. The SEQ ID of the polypeptide is as disclosed in the specification.
Patent NZ-597376-A (NZ)
Title: Furazanobenzimidazoles as prodrugs to treat neoplastic or autoimmune diseases
Inventor: BACHMANN FELIX
IPC: A61P35/00
Filed: 2010-07-26
Abstract: A compound of formula (II) wherein (a) represents a divalent benzene residue which is unsubstituted or substituted by one or two additional substituents independently selected from lower alkyl, halo-lower alkyl, hydroxy-lower alkyl, lower alkoxy-lower alkyl, acyloxy-lower alkyl, phenyl, hydroxy, lower alkoxy, hydroxy-lower alkoxy, lower alkoxy-lower alkoxy, phenyl-lower alkoxy, lower alkylcarbonyloxy, amino, mono(lower alkyl)amino, di(lower alkyl)amino, mono(lower alkenyl)amino, di(lower alkenyl)amino, lower alkoxycarbonylamino, lower alkylcarbonylamino, substituted amino wherein the two substituents on nitrogen form together with the nitrogen heterocyclyl, lower alkylcarbonyl, carboxy, lower 15 alkoxycarbonyl, cyano, halogen, and nitro; or wherein two adjacent substituents can be methylenedioxy; or a divalent pyridine residue (Z = N) which is unsubstituted or substituted additionally by lower alkyl, lower alkoxy, lower alkoxy-lower alkoxy,amino, optionally substituted by one or two substituents selected from lower alkyl, lower alkenyl and alkylcarbonyl, halo-20 lower alkyl, lower alkoxy-lower alkyl, or halogen; R1 represents hydrogen, lower alkylcarbonyl, hydroxy-lower alkylor cyano-loweralkyl; and R2 represents a group selected from: (b), (c) and (d); or pharmaceutically acceptable salts thereof.
Patent NZ-600290-A (NZ)
Title: Disc tumbler cylinder lock and key combination with a rotation limiter which is prevented from rotating when a key is not in the lock
Inventor: KIISKI SEPPO
IPC: E05B21/06
Filed: 2010-12-08
Abstract: 600290 The application relates to a disc tumbler cylinder lock and key combination. The disc tumbler cylinder lock (1) of the combination comprises rotation limiting means (3) of the key, and the key (9) comprises guidance surfaces (10) for the rotation limiting means. The rotation limiting means comprise a frame (6), which comprises a key profile opening (4), and a casing (5), which at least partially surrounds the frame. The frame (6) comprises a limiting mechanism (24) and a locking mechanism (25), which are disposed in a line such that the limiting mechanism is on the other side of the key profile opening (4) and the locking mechanism (25) is on the opposite side of the key profile opening.
Patent NZ-602641-A (NZ)
Title: Self-contained motorization system
Inventor: JUAN ANTOINE
IPC: B60L11/18
Filed: 2011-03-29
Abstract: 602641 Disclosed is a self-contained motorization system including at least one electric motor (9), a controller adapted to drive the operation of the electric motor (9) and a set of accumulators of power type (5) adapted to feed the motor (9) by providing the instantaneous current consumed by the motor (9). A central control unit (7) commands a direct current converter and a base (3) removably receives a set of accumulators of energy type (4). The system also includes a direct current converter adapted to connect the set of accumulators of energy type (4) to the set of accumulators of power type (5) to control the charge of the set of accumulators of power type (5) by the set of accumulators of energy type (4) by providing a charge current to the set of accumulators of power type (5) that compensates on average the energy supplied to the motor. The set of accumulators of power type (5) are capable of supplying the maximum current sought by the motor (9).
Patent NZ-607428-A (NZ)
Title: Pure intermediate for preparing letrozole
Inventor: GORE VINAYAK GOVIND
IPC: C07D249/08
Filed: 2011-08-26
Abstract: Disclosed is the oxalic acid addition salt of 4-[(1,2,4-triazol-1-yl)methyl]benzonitrile (III). Further disclosed is a process for the preparation of 4-[(1,2,4-triazol-1-yl)methyl]benzonitrile (III), comprising the purification of the oxalic acid addition salt of 4-[(1,2,4-triazol-1-yl)methyl]benzonitrile (III), and subsequent liberation of 4-[(1,2,4-triazol-1-yl)methyl]benzonitrile (III) from the purified salt. Also disclosed is a process for the preparation of letrozole (4-[1-(4-cyanophenyl)-1-(1,2,4-triazol-1-yl)methyl]-benzonitrile), or a pharmaceutically acceptable salt thereof, wherein the process comprises the conversion of 4-[(1,2,4-triazol-1-yl)methyl)]benzonitrile (III) or the oxalic acid addition salt prepared as defined herein into Letrozole or a pharmaceutically acceptable salt thereof, wherein the 4-[(1,2,4-triazol-1-yl)methyl)]benzonitrile (III) or the salt thereof is reacted with 4-fluorobenzonitrile (IV) in the presence of a base.
Patent NZ-613338-A (NZ)
Title: Method for in-situ manufacture of a lightweight fly ash based aggregate
Inventor: PEREZ-PENA MARIANELA
IPC: C04B22/14
Filed: 2011-12-13
Abstract: A method of making a rapid setting lightweight homogeneous foamed fly ash based cementitious loose aggregate composition with improved compressive strength for products such as panels is disclosed, wherein the method consists of the following steps: forming a mixture by mixing ingredients consisting essentially of: water; cementitious reactive powder consisting essentially of fly ash and a calcium sulfate selected from the group consisting of calcium sulfate hemihydrate, calcium sulfate dihydrate, and mixtures thereof, and optional silica fume; an alkali metal salt of citric acid selected from the group consisting of sodium citrate, potassium citrate and mixtures thereof; a foaming agent for entraining air; and optionally at least one or more member selected from the group consisting of secondary aggregate other than said loose aggregate, superplasticizer, set accelerating agents other than said alkali metal salt of citric acid, set retarding agents, shrinkage control agents, thickening agents, coloring agents, and internal curing agents; and reacting the mixture in situ at a temperature of 20 °C to 41 °C by mixing for 3 to 6 minutes to form aggregate particles comprising hydration products of the fly ash and calcium sulfate in the mixture and crystalline hydration products of the fly ash and calcium sulfate which are also formed in situ and are interspersed within and between the aggregate particle to bind the aggregate particles; and separating the aggregate particles as loose aggregate particles from the mixture.
Patent NZ-621235-A (NZ)
Title: Improved nitric acid production
Inventor: SUCHAK NARESH J
IPC: B01D53/56
Filed: 2012-08-21
Abstract: Disclosed is a method for reducing the levels of nitrogen oxides in the tail gas (15) from a nitric acid production process by adding ozone at the final absorption stages of the absorber column (F) of the production process. Also disclosed is the enhancement of nitric acid production by adding a mixture of secondary air and oxygen (18) to the absorber column.
Patent NZ-625687-A (NZ)
Title: Process and system for conversion of carbon dioxide to carbon monoxide
Inventor: OLAF KÜHL
IPC: C01B32/40
Filed: 2012-12-20
Abstract: A process and an apparatus for converting carbon dioxide CO2 into carbon monoxide CO using hydrocarbons are described. In further embodiments, processes and apparatuses for generating synthesis gas and processes and apparatuses for converting synthesis gas into synthetic functionalised and/or non-functionalised hydrocarbons using CO2 and hydrocarbons are described. The processes and apparatuses are adapted to convert CO2 emitted by industrial processes, and thus the amount of carbon dioxide emitted into the atmosphere may be reduced.
Patent NZ-628421-A (NZ)
Title: Treatment of cancer with tor kinase inhibitors
Inventor: XU SHUICHAN
IPC: A61P35/00
Filed: 2013-03-14
Abstract: Provided herein are methods for treating or preventing ETS overexpressing Ewings sarcoma, comprising administering an effective amount of a TOR kinase inhibitor such as 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one to a patient having ETS overexpressing Ewings sarcoma.
Patent NZ-631044-A (NZ)
Title: Manufacture of 2-(5-bromo-4(-cyclopropylnaphthalen-1-yl)-4h-1,2,4-triazol-3-ylthio)acetic acid
Inventor: GUNIC ESMIR
IPC: C07D249/12
Filed: 2013-07-02
Abstract: Disclosed is processes for the synthesis of 2-(S-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl-thio)acetic acid (compound of formula III) comprising brominating a precursor compound with N-bromosuccinimide (NBS) and a solvent.
Patent NZ-700641-A (NZ)
Title: Method for preparation of 2-(2,3-dimethylphenyl)-1-propanal
Inventor: ZARAGOZA DOERWALD FLORENCIO
IPC: C11B9/00
Filed: 2012-11-15
Abstract: The invention discloses a method for preparation of a compound of formula (XXI); the method comprises a step (N); step (N) comprises a reaction (N-reac); reaction (N-reac) is a reaction of compound of formula (XXII) with a catalyst (N-cat); catalyst (N-cat) is selected from the group consisting of acetic acid, formic acid, trifluoroacetic acid, methanesulfonic acid, benzenesulfonic acid, p-toluenesulfonic acid, camphorsulfonic acid, HCl, HBr, H2SO4, HNO3, H3PO4, HClO4, BCl3, BBr3, BF3OEt2, BF3SMe2, BF3THF, MgCl2, MgBr2, MgI2, AlCl3, Al(O C1 4 alkyl)3, SnCl4, TiCl4, Ti(O C1 4 alkyl)4, ZrCl4, Bi2O3, BiCl3, ZnCl2, PbCl2, FeCl3, ScCl3, NiCl2, Yb(OTf)3, Yb(Cl)3, GaCl3, AlBr3, Ce(OTf)3, LiCl, Cu(BF4)2, Cu(OTf)2, NiBr2(PPh3)2, NiBr2, NiCl2, Pd(OAc)2, PdCl2, PtCl2, InCl3, acidic inorganic solid substance, acidic ion exchange resin, carbon treated with inorganic acid and mixtures thereof. The invention is also directed towards the use of the compound of formula (XXI), its use in perfumes and its use for the preparation of medetomidine.
Patent NZ-705260-A (NZ)
Title: Aerosol pirfenidone and pyridine analog compounds for the treatment of lung disease
Inventor: SURBER MARK WILLIAM
IPC: A61K31/4418
Filed: 2013-07-24
Abstract: Disclosed herein are formulations of pirfenidone or pyridone analog compounds for aerosolization and use of such formulations for aerosol administration of pirfenidone or pyridone analog compounds for the prevention or treatment of various fibrotic and inflammatory diseases, including disease associated with the lung, heart, kidney, liver, eye and central nervous system. In some embodiments, pirfenidone or pyridone analog compound formulations and delivery options described herein allow for efficacious local delivery of pirfenidone or pyridone analog compound. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures, indications and manufacturing processes for production and use of the compositions described.
Patent NZ-708362-A (NZ)
Title: A connector
Inventor: CUMMINGS STEPHEN JOHN
IPC: F16L27/00
Filed: 2012-05-22
Abstract: Disclosed is a sewerage connecter that allows connection from a toilet S-trap flushing outlet, bath or basin waste outlet to an out of alignment waste pipe inlet. The connector includes a first part with an inlet end including a seal for sealing relative to the toilet flushing outlet, adapted for connection to the waste outlet, and an outlet end; and a second part with an inlet end, adapted for rotational connection to the outlet end of the first part, and a second end, adapted for connection to the sewer waste inlet. The first part outlet end is eccentrically offset relative to the first part inlet end and the second part inlet end is eccentrically offset relative to the second part outlet end.
Patent NZ-717192-A (NZ)
Title: Anti-inflammatory tripeptides
Inventor: ABELS CHRISTOPH
IPC: C07K5/09
Filed: 2014-09-23
Abstract: The present invention relates to tripeptide compounds according to the general formula (1) and their use as a medicament, in particular as anti-inflammatory agents.
Patent NZ-721975-A (NZ)
Title: Novel anti-netrin-1 antibody
Inventor: DELCROS JEAN-GUY
IPC: C07K16/22
Filed: 2015-01-09
Abstract: The application discloses a linear or substantially linear epitope on netrin-1 that likely corresponds to the specific binding region of netrin-1 to receptor, in particular of the UNC5 class, especially UNC5B and UNC5A, or alternatively corresponds to a region nearby the specific binding region of netrin-1 to receptor that when bound to an antibody prevents netrin-1/receptor interaction. This determination of a linear epitope allows the Applicant to produce antibodies binding to netrin-1 and interfering with netrin-1/receptor interaction, thereby inducing apoptosis or cell death of tumour cells expressing or overexpressing netrin-1 and at least one netrin-1 receptor, owing the fact that this interaction inhibits netrin-1 binding to a receptor and the multimerization of the receptor. The application discloses a murine monoclonal antibody directed against this epitope and various humanized forms thereof.
Patent NZ-746925-A (NZ)
Title: Chimeric receptors to flt3 and methods of use thereof
Inventor: BAKKER ALICE
IPC: C07K16/28
Filed: 2017-03-31
Abstract: Antigen binding molecules, chimeric receptors, and engineered immune cells to FLT3 are disclosed in accordance with the invention. The invention further relates to vectors, compositions, and methods of treatment and/or detection using the FLT3 antigen binding molecules and engineered immune cells.
Patent NZ-751499-A (NZ)
Title: Il-22 polypeptides and il-22 fc fusion proteins and methods of use
Inventor: SCHEER JUSTIN
IPC: A61K38/20
Filed: 2014-03-14
Abstract: The invention relates to monomeric IL-22 Fc fusion proteins, wherein the fusion proteins have a first arm that is an IL-22 Fc fusion arm and a second arm that is an Fc arm that have knob-in-hole modifications to improve heterodimerisation thereof, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
Patent NZ-759579-A (NZ)
Title: Sensor system
Inventor: FUNG TRACY HELEN
IPC: H01L27/146
Filed: 2017-12-26
Abstract: A system includes an image sensor structure and a flow cell. The image sensor structure includes an image layer disposed over a base substrate. A device stack is disposed over the image layer. A bond pad is disposed in the device stack. A passivation stack is disposed over the device stack and the bond pad. An array of nanowells is disposed in a top layer of the passivation stack. A through-silicon via (TSV) is in electrical contact with the bond pad. The TSV extends through the base substrate. A redistribution layer (RDL) is disposed on a bottom surface of the base substrate. The RDL is in electrical contact with the TSV. The flow cell is disposed upon the top layer of the passivation stack to form a flow channel therebetween. The flow channel is disposed over the array of nanowells and the bond pad.
Patent NZ-771639-A (NZ)
Title: Tracking vehicles in a warehouse environment
Inventor: ECKMAN CHRISTOPHER FRANK
IPC: G06Q10/08
Filed: 2019-05-30
Abstract: Warehouses include warehouse racks to store pallets of goods. Pallets are generally flat transport structures that support goods in a stable matter and that are adapted to fit forklifts and/or other devices/machines to move the pallets. Packages of various products can be stacked on top of the pallets. Warehouses have been designed to permit forklifts to put and pull pallets from racks as needed. Forklifts and other sorts of vehicles move through a warehouse and transport pallets and packages. This specification generally discloses technology for tracking vehicle positions in a warehouse environment. A system receives stereoscopic image data from a camera on a forklift, in some implementations. The system recognizes an object that is represented in the stereoscopic image data, identifies a representation of the recognized object in a spatial model that identifies, for each of a plurality of objects in an environment, a corresponding location of the object in the environment, determines the location of the recognized object in the environment, determines a relative position between the forklift and the recognized object, based on a portion of the received stereoscopic image data that represents the recognized object, and determines a location of the forklift in the environment, based on the determined location of the recognized object in the environment, and the determined relative position between the forklift and the recognized object.
Patent NZ-775906-A (NZ)
Title: High temperature superconductor magnet
Inventor: BRITTLES GREG
IPC: H01F41/10
Filed: 2019-10-14
Abstract: A High Temperature Superconductor, HTS, magnet comprising a coil formed of nested concentric windings. Each winding comprises HTS material. The HTS magnet further comprises a conductor element comprising an electrical contact surface through which to supply electric current to a portion of at least one of the windings. The surface provides electrical contact between the conductor element and an axial edge of the coil substantially around the path of the at least one of the windings.