baber/WOPTO huggingface dataset:
Patent CY-1116458-T1 (CY)
Title: Ανθρωπινα αντισωματα anti-cd38 και οι χρησεις εξ' αυτων
Inventor: TESAR MICHAEL
IPC: C07K16/00
Filed: 2015-07-02
Abstract: Η παρούσα εφεύρεση παρέχει ανασυνδυασμένες περιοχές δέσμευσης-αντιγόνων και αντισώματα και λειτουργικά θραύσματα που περιέχουν τέτοιες περιοχές δέσμευσης-αντιγόνων που είναι συγκεκριμένες για το CD38, το οποίο διαδραματίζει ολοκληρωτικό ρόλο σε διάφορες διαταραχές ή καταστάσεις. Αυτά τα αντισώματα, συνεπώς, μπορούν να χρησιμοποιηθούν για την αγωγή, για παράδειγμα, αιματολογικών κακοηθειών όπως είναι το πολλαπλό μυέλωμα. Τα αντισώματα της εφεύρεσης μπορούν επίσης να χρησιμοποιηθούν και στο διαγνωστικό πεδίο, ως επίσης και για διερεύνηση του ρόλου του CD38 στην πρόοδο διαταραχών που συσχετίζονται με κακοήθειες. Η εφεύρεση παρέχει επίσης και αλληλουχίες πυρηνικών οξέων που εγκωδικεύουν τα προειρημένα αντισώματα, ανύσματα που περιέχουν τα ίδια, φαρμακευτικές συνθέσεις και κιτ με οδηγίες για χρήση. Η εφεύρεση παρέχει επίσης και απομονωμένους καινοφανείς επίτοπους του CD38 και μεθόδους για χρήση ως εκ τούτου.
Patent CY-1119483-T1 (CY)
Title: Θεραπευτικος παραγων για τις αγχωδεις διαταραχες
Inventor: KASE JUNYA
IPC: C07D495/04
Filed: 2017-10-04
Abstract: Παρέχονται ένας παράγων για την αγωγή και/ή την προφύλαξη από μία αγχώδη διαταραχή ο οποίος περιλαμβάνει, ως δραστικό συστατικό, ένα παράγωγο του θειαζολίου που αναπαριστάται από τον τύπο (I) όπου το R1 αναπαριστά αρύλιο ή παρόμοιο, και το R2 αναπαριστά πυριδύλιο ή παρόμοιο, ή ένα φαρμακευτικά αποδεκτό άλας αυτού, και παρόμοια.
Patent CY-1119925-T1 (CY)
Title: Aνti-cd40 αντισωματα, χρησεις και μεθοδοι
Inventor: ELLMARK PETER BO JOAKIM
IPC: C07K16/28
Filed: 2018-02-09
Abstract: Η παρούσα εφεύρεση αναφέρεται σε αντισώματα (και σε θραύσματα, παραλλάγματα, συγχωνεύσεις, και παράγωγα αυτών) με εξειδίκευση πολυσθενούς πρόσδεσης για την CD40, τα οποία έχουν μια ικανότητα για ενεργοποίηση δενδριτικών κυττάρων η οποία είναι υψηλότερη από, ή ίση με, την ικανότητα για ενεργοποίηση Β κυττάρων και όπου το αντίσωμα, θραύσμα πρόσδεσης αντιγόνου, ή συγχώνευση, παράλλαγμα ή παράγωγο αυτού έχει μια συγγένεια (KD) για την CD40 λιγότερο από 1x10-10 Μ, το οποίο έχει χρησιμότητα στη θεραπευτική αγωγή νόσων όπως ο καρκίνος. Η εφεύρεση αναφέρεται επίσης σε φαρμακευτικές συνθέσεις, χρήσεις, μεθόδους και κυτία που περιλαμβάνουν τέτοια αντισώματα.
Patent CY-1122654-T1 (CY)
Title: Ενωσεις για βελτιωμενη iiκη μεταγωγη
Inventor: HEFFNER GARRETT COLLINS
IPC: C12N5/0789
Filed: 2020-01-22
Abstract: Η παρούσα εφεύρεση παρέχει μεθόδους και συνθέσεις για τη βελτίωση της αποτελεσματικότητας ιικής μεταγωγής κυττάρων. Ειδικότερα, η παρούσα εφεύρεση παρέχει μεθόδους και υλικά χρήσιμα για ασφαλή και αξιόπιστη βελτίωση της αποτελεσματικότητας των μεθόδων για την μεταγωγή κυττάρων, όπως αιμοποιητικά βλαστοκύτταρα ανθρώπου (HSC), με ιούς και/ή ιικούς φορείς. Οι συνθέσεις και μέθοδοι είναι χρήσιμες για θεραπευτικές ενδείξεις επιδεκτικές θεραπείας με γονιδιακές θεραπείες αιματοποιητικών βλαστοκυττάρων.
Patent SI-1606233-T1 (SI)
Title: Phospholipid esters of Clofarabin
Inventor: HERRMANN DIETER
IPC: A61K31/00
Filed: 2004-03-18
Abstract: The subject of the present invention are specific lipidesters of halogenated-adenine nucleotides and the use of such lipidesters in the treatment of tumors.
Patent SI-1615699-T1 (SI)
Title: Benzoxazinyl-amidocyclopentyl-heterocyclic modulators of chemokine receptors
Inventor: GOBLE STEPHEN D
IPC: A61K31/00
Filed: 2004-04-09
Abstract: Cyclopentyl compounds linked to a benzoxazinyl group through an amido moiety utilizing the ring nitrogen of the benzoxazine, and further substituted with a heterocyclic moiety, such compounds represented by formula I: which are used to modulate the CCR-2 chemokine receptor to prevent or treat inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis; and pharmaceutical compositions comprising these compounds and the use of these compounds and compositions.
Patent SI-1851023-T1 (SI)
Title: Method and device for granulating plastics and/or polymers
Inventor: ELOO MICHAEL
IPC: B29C48/92
Filed: 2006-02-15
Abstract: The valve housing(2) has one flow path from a first connector(3) for a melt supply via a melt channel to a first granulator connector(5). A second flow path runs between a second melt supply connector(4) and a second granulator connector(6) via a separate, second melt channel. The first and/or second melt channels have a start-up flow diverting valve. In the production position the valve opens a connection between the first melt supply connector(3) and the first granulator connection(5) and/or a connection between the second melt supply connector(4) and the second granulator connection(6). In the start-up position the valve closes the link between the first granulator connection and first melt supply connector and/or the link between the second granulator connector and the second melt supply connector and/or connects the second melt connector to a by-pass opening for dumping melt. Start-up diverting valves for both the first and second melt channels are connected to each other and operated by a common actuator so that both valves can be simultaneously set their production or start-up position. Both valves are in a common valve body. In a design variation the second granulator connector may be linked to a melt channel and a diverting valve connects the first melt supply connector to either the first or second granulator connector. In the latter design a third granulator connector connects with the melt channel and is linked to the melt supply connector by the diverting valve. The start-up diverting valve has a cylindrical body with separate production flow channels and moves axially between the different positions. One or more by-pass channels are incorporated in a valve body. Quick release couplings link the melt supply and granulator connectors to a melt source and granulator.
Patent SI-1888983-T1 (SI)
Title: A cooling device and the control method
Inventor: SOYSAL ALPER
IPC: F25B49/00
Filed: 2006-05-26
Abstract: The present invention relates to a cooling device (1) and a control method thereof, which prevent the motor of a variable speed compressor (2) performing the refrigerant cycle from unexpected stalls due to reasons of overheating or not being able to respond to the thermodynamic load resulting from heavy work load like high ambient temperature or the frequent opening closing of the door by means of a control method implemented via a control card (5).
Patent SI-2205620-T1 (SI)
Title: Amorphous form of (11beta,16alpha)-9-fluoro-11-hydroxy-16,17-?á(1-methylethyliden)bis(oxy)?å-21-?á?á4- ?á(nitrooxy)methyl?åbenzoyl?åoxy?å-pregna-1,4-dien-3,20-dione
Inventor: ANGLADA LUIS
IPC: A61K31/57
Filed: 2008-10-23
Abstract: The invention relates to the technical field of anti-inflammatory compounds, specifically those of a steroid nature, in particular to a new amorphous form of a nitrooxy derivative of a corticosteroid, its pharmaceutical formulations and its use in the treatment or prevention of diseases or symptoms of the skin or mucous membranes.
Patent SI-2082837-T1 (SI)
Title: Crimping pliers
Inventor: BATTENFELD KURT
IPC: B25B7/00
Filed: 2009-01-07
Abstract: Pressing tongs (1) comprises a closing mechanism (48) which is actuated depending on hand levers (2, 3) and pressing jaws (23, 24) which move from an opening position into a closed position using the closing mechanism. The pressing jaws are secured in the starting position to prevent a return to the opening position. Preferred Features: The closing mechanism is formed as a ratchet mechanism.
Patent TR-201010974-T1 (TR)
Title: Yük Durumu Kontrollü Güç Devresi
Inventor: DUBOSE RICHARD G
IPC: H01R13/70
Filed: 2009-06-09
Abstract: Mevcut buluşun çeşitli gorünümlerine uygun olarak, bir güç kablosu, duvar prizi devresi, güç modülü ve benzerlerinin güç tüketiminin azaltılması için bir yöntem ve devre sağlanmaktadır. Örnek bir oluşumda güç devresi, elektrik bağlantısının bir güç girişinden kesilmesi yoluyla, bekleme modu sırasında gücün azaltılması veya kesilmesi için yapılandırılır. Örnek bir güç devresi, bir AC hattı girişi ile iletişim halinde olabilir ve bir akım transformatörü, bir kontrol devresi ve bir anahtar içerebilir. Akım transformatörü sekonder sargısı, güç çıkışı yükünün bir oranı kadar çıkış sinyali gönderir. Akım transformatörü sekonder sargısının davranışı, güç devresinin AC hattı girişinden hemen hemen hiç güç  çekmediğini gösterdiği takdirde anahtar, akım transformatörü primerinin güç devresinden kesilmesini sağlar.
Patent DE-3072209-T2 (DE)
Inventor: MOSIMANN DAVID
IPC: A61C1/06
Filed: 1980-02-18
Granted: 1994-06-01
Abstract: PCT No. PCT/CH81/00019 Sec. 371 Date Oct. 19, 1981 Sec. 102(e) Date Oct. 19, 1981 PCT Filed Feb. 18, 1981 PCT Pub. No. WO81/02249 PCT Pub. Date Aug. 20, 1981.The dental instrument with handpiece comprises an intermediate section (4) containing a micromotor. A handpiece (1) with a head (2) carrying a tool (3) is plugged in the front end of the intermediate section (4) so as to form a unit block therewith. At the back end thereof, the intermediate section (4) carries an adaptor comprising a part (10) integral with said section (4), and a part (9) which may rotate freely in the part (10) about the instrument axis. Said part (9) receives the adapter (8) integral therewith, of a flexible sheath (7) which connects the instrument to a supply station and brings thereto, besides the power and driving flux for the micromotor, air and water for a jet (15) of fine water droplets in the direction of the work location, as well as a lighting through an optical fiber thereof, through conduits (6,11,12,13,21) contained in the sheath (7) and going through the adaptor (9,10) separately.
Patent DE-3878198-T2 (DE)
Inventor: DE JONGH HENDRIK PAUL
IPC: C07J41/00
Filed: 1988-11-25
Granted: 1993-06-24
Abstract: The invention relates to new 11-arylsteroid compounds, having a strong antiprogestin and a weak or nonexistent antiglucocorticoid activity, to processes for preparing said compounds and also to pharmaceutical preparations which contain these derivatives as active constituent, characterized in that said steroids have the following formula: <CHEM>  in which  R1      is an aryl group with a - @@@X   group as substituent, X and Y each being separately H or a (1-4 C) hydrocarbyl group or together a (2-6 C) hydrocarbyl group which forms a 3- to 7-membered ring together with the nitrogen atom; R2      is hydrogen, hydroxyl, an acyloxy or an alkoxy group or a saturated or unsaturated hydrocarbyl group containing 1-8 carbon atoms, which hydrocarbyl group is provided with at least one hydroxyl, oxo, azido, cyano and/or halogen group; R3      is a hydroxyl, an acyloxy or an alkoxy group or an acyl group optionally substituted by a hydroxyl, alkoxy, acyloxy or halogen group; or R2 and R3 together form a ring system, with the proviso that if R3 is hydroxyl, R2 is not hydrogen or hydroxyl; and  R4 is a methyl or ethyl group; and the  alpha - and  beta -bonds are indicated by dashed (---) and wedged ( @) lines respectively.
Patent DE-3880732-T2 (DE)
Inventor: GILL DAVID CHARLES
IPC: G05D7/06
Filed: 1988-05-13
Granted: 1993-08-19
Abstract: There is disclosed an electronic control means for a pump, the control means comprising: input means, for accepting input signals, the input signals being indicative of the values of variable quantities which determine a desired flow rate of a fluid which, in use, is to be supplied by a pump; an electronic memory, comprising a plurality of memory locations, each memory location corresponding to a particular combination of values of the variable quantities and containing a stored control signal corresponding to the desired fluid flow rate determined by those values; and output means, for supplying the control signal, in use, to the pump.   More specifically, there is diclosed equipment suitable for distributing a fluid over an area of land, the equipment comprising distribution means, to which fluid is supplied by a pump driven by an electric motor, the delivery rate of the fluid from the pump being a function of the operating speed of the pump, the equipment further comprising such control means.
Patent DE-3884875-T2 (DE)
Inventor: DUJARI VINEET
IPC: G11B20/18
Filed: 1988-07-05
Granted: 1994-04-14
Abstract: A novel technique for skipping defects on a magnetic or writable optical disk is described. The technique includes a sector format comprising a header (24) and data area (28), wherein the data area can include one or more "bad areas" (108, 116) which will be skipped when data is being written to or read from the sector. The bad areas are variable in size and may be located anywhere in the data area, including in an EDAC. The header includes a defect descriptor (48) comprising a defect pointer (70, 72) for each of the bad areas supported. Each defect pointer contains a value (74, 78) indicating the number of bytes in the good data area (106, 114) preceding the bad area pointed to by the defect pointer, and a value (76, 80) indicating the number of bytes in the bad area. The value indicating the number of bytes in a good area is set to a value indicating a number of bytes as least as large as the sector size if there is no subsequent bad area in the data area. A method for reading or writing data to a sector formatted as above is also described. A method for formatting a disk as above is described as well.
Patent DE-3886064-T2 (DE)
Inventor: AUTRY FARRELL
IPC: B65D88/68
Filed: 1988-02-18
Granted: 1994-04-14
Abstract: The present invention is directed to a cutting tip device (31), and method of using the device (31), for removing the build-up of particulate (24) from an internal surface of a storage bin (23), such as a coal bunker or a grain silo (23). The cutting tip (31) is attached to a source of compressed gas by a hose, and includes at least one internal gas passageway (35) through which the compressed gas is forced. The compressed gas is at a predetermined minimum pressure and flow rate sufficient to cause the cutting tip (31) to gyrate in an erratic fashion about the hose, and to strike the build-up (24) with sufficient force to remove the particulate (24) from the interior of the storage bin (23). By lowering a hose having the cutting tip (31) attached to it into a storage bin (23) and forcing compressed gas through the hose and cutting tip (31), the interior of the storage bin (13) is cleared of its build-up (24).
Patent SI-1956015-T2 (SI)
Title: Polymorph of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and method of producing the same
Inventor: MATSUMOTO KOICHI
IPC: C07D277/00
Filed: 1999-06-18
Abstract: The present invention provides a technique of selectively producing a desired polymorph of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid.  The present invention also provides a method of producing various polymorphs of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid, which comprises crystallizing under the conditions defined by a specific temperature and a composition of a mixed solvent of methanol and water, and polymorphs obtained by the method.  The present invention further provides a method of producing the other polymorphs or amorphous compounds by drying a specific polymorph under a reduced pressure with heating, and the other polymorphs or amorphous compounds obtained by the method.
Patent TR-199900056-T2 (TR)
Title: Leptin direncinin yeni tedavisi.
Inventor: POSTE GEORGE HENRY
IPC: A61K31/427
Filed: 1997-07-14
Abstract: Leptin direncinin ve/veya leptin direnciyle baglantili durumlarin ve/veya komplikasyonlarinin tedavisi ve/veya önleyici tedavisi için, bir leptin sensitizöründen veya farmasötik olarak kabul edilebilir bir türevinden etkili, toksik-olmayan ve farmasötik olarak kabul edilebilir bir miktada içten verilmesini içeren bir yöntem.
Patent TR-199901528-T2 (TR)
Inventor: CAMDEN JAMES BERGER
IPC: A61P35/00
Filed: 1997-11-26
Abstract: Memelilerde tümör ve kanserlerin büyümesini engelleyen viral enfeksiyonlarin tedavisinde kullanilabilecek fungusit ihtiva eden bir farmasötik bilesim ifsa edilmistir. Kullanilan özel fungusit asagidaki formüle haiz bir benzimidazol türevidir. Bu formülde R, H, karboksil (-CO2H), hidroksil, amino veya R''nün, alkoksi, haloalkil, alkenil arasindan seçildigi esterler (-CO2R') veya alkil guruplari 1-8 karbon içeren sikloalkil veya n'nin 1 ila 3 arasinda oldugu CH3CH2(OCH2CH2)n- veya CH3CH2CH2(OCH2CH2)n- veya (CH3)2CH-(OCH(CH3)CH2)n- veya bunlarin farmasötik olarak etkin organik veya inorganik tuzlari veya bunlarin karisimlarinin olusturdugu guruptan seçilir.
Patent TR-199902838-T2 (TR)
Inventor: B-JENSEN BERNT-INGE
IPC: B65H49/08
Filed: 1997-05-20
Abstract: The invention concerns a container (1) for packaging and unwinding a coil of welding wire, which comprises a box-like body (4) having inner walls (5b) forming a polygonal periphery for accomodating a circular coil (2) of wire (3) during the transportation and the unwinding of the coil (2). The container also comprises a cover (6) at the upper end of the body (4), a bottom (26) at the lower end of the body, a retainer device (17) arranged inside the body on the coil for preventing accidental entanglement of the wire turns during the unwinding of the wire from the coil, and a wire conduit device (10) for the guidance of the wire out from the body during the unwinding. At least in some places the retainer device (17) is in contact with the inner walls of the body, especially during the unwinding. The cover (6) is flat and is placed at the top of the body both during the transportation and the unwinding of the wire (3). The wire conduit device (10) is attached to the cover during the unwinding.
Patent DE-60000252-T2 (DE)
Inventor: LOPEZ THIERRY
IPC: G07C5/10
Filed: 2000-03-15
Granted: 2002-12-12
Abstract: The program file transfer commences with compression of (2) of the file (1). The compressed file is then transferred (3) to the vehicle while it is at a station in the assembly line. Decompression of the file is triggered (4) when the vehicle moves on to another station in the assembly line.
Patent DE-60000320-T2 (DE)
Inventor: LABASQUE JACQUES
IPC: B01D53/04
Filed: 2000-02-10
Granted: 2003-03-13
Abstract: A new adsorbent for separating gases contains particles of a zeolite with an Si/Al ratio less than or equal to 5, chosen fro or A type zeolites. The zeolite has a kinetic coefficient ak 0.5 s<-1> and an intrinsic resistance  alpha  such 0.10  alpha  2. An Independent claim is also included for a PSA (pressure swing adsorption) process for separating gas components of differ absorbability, using the zeolite (which may additionally be of the Y type).
Patent DE-60001756-T2 (DE)
Inventor: NOLI MARIO
IPC: G01K1/08
Filed: 2000-12-05
Granted: 2003-12-24
Abstract: A method for manufacturing a sealed temperature probe, including a cable (C) provided with at least a pair of conducting wires (F) insulated by respective sheaths (P) and ending with an exposed length where a sensor (S) is soldered, provides the introduction of the sensor (S) and exposed length of wires (F) into a covering element prior to the overmoulding of the probe terminal with a thermoplastic material (M) same as or compatible with the material of the sheaths (P). In the probe thus manufactured the covering element may be either the end portion of an outer sheath (G) or a covering tube (N), possibly long enough to be slipped on the cable (C) and/or made with two layers of different materials coupled so as to form a single element. <IMAGE>
Patent DE-60007155-T2 (DE)
Inventor: BUMPSTEED AUSTIN
IPC: B26F1/04
Filed: 2000-09-29
Granted: 2004-06-03
Abstract: An edge punching machine comprises a punching slot (38) into which a stack of material to be edge-punched may be located, and a punching device (80, 90) comprising a plurality of punch members (81, 91) moveable through the punching slot to punch holes in the stack. Location means (156, 126, 81) is provided to locate the edge of the stack and hence spacing between the edge of the stack and the array of punched holes. The location means comprises a plurality of support members (156, 126, 81) extending in the punching slot (38) to support the stack at spaced intervals, whereby any clippings which may enter the punching slot will drop between said members and will not affect the spacing in subsequent punching operations. Conveniently the machine comprises two punching devices (80, 90), each comprising a different plurality of punch members (81, 91) and the location means is conveniently provided by the punch members (81) of one of said punching devices (80).
Patent DE-60011710-T2 (DE)
Inventor: DA SILVA-JARDINE PAUL ANDREW
IPC: A61K9/70
Filed: 2000-05-30
Granted: 2005-06-30
Abstract: This invention provides a method for transdermal delivery of estrogen agonists - antagonists which are effective for treating or preventing conditions related to estrogen imbalance.
Patent DE-60016146-T2 (DE)
Inventor: GARLASCHI EUFEMIA
IPC: B21F23/00
Filed: 2000-11-24
Granted: 2005-12-01
Abstract: A handling apparatus for forging machines, especially for drawing wire (52) intended for realizing screws, rivets and like findings, comprises:   a first cam (12) keyed on a first motor-driven rotary shaft (10), cooperating with a first angularly orientable lever (14), associated to a roller (16) and formed by a branch (14') having a rectilinear portion (18) suitable to place itself parallel with respect to a screw 820), guided by a support (22) and caused to rotate clockwise or anti-clockwise by an electric motor (24) or by hand; a sliding carriage (32), associated to screw (20), provided with a transversal tying pin (34) for an oscillating bar (36) bearing on its free end a needle (40) that strikes said portion (18) of the first lever (14); a second angularly orientable lever (14), cooperating with a carriage (50) movable in a direction parallel to the one of advance of the wire (52);   means (56, 60) for grasping wire (52); a second cam (70) mounted on a second shaft or rotary side shaft (72) of the forging machine, cooperating with a needle (74) fixed to the lower end of a third lever (76) pivoted on a static support of said forging machine.   <IMAGE>
Patent DE-60024808-T2 (DE)
Inventor: COSMAN J
IPC: C12N15/09
Filed: 2000-05-12
Granted: 2006-10-05
Abstract: A family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridizes to defmed nucleotide sequences, processes for producing polypeptides of the LIR family, and specific antibodies directed against LIR polypeptides. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.
Patent DE-60025036-T2 (DE)
Inventor: GERDIL CATHERINE
IPC: C12N5/08
Filed: 2000-12-04
Granted: 2006-06-22
Abstract: The invention concerns a culture medium containing a polyvinylpyrrolidone as substitute for the serum of animal origin for producing animal or human adherent cells under stirring by increasing the cell proliferation or by decreasing cell death rate. Said medium is also suitable for producing viruses.
Patent DE-60025588-T2 (DE)
Inventor: ROMACK J
IPC: D06L1/00
Filed: 2000-01-19
Granted: 2006-11-09
Abstract: A method for dry-cleaning articles such as fabrics and clothing in carbon dioxide comprises contacting an article to be cleaned with a liquid dry cleaning composition for a time sufficient to clean the fabric. The liquid dry-cleaning composition comprises a mixture of carbon dioxide, a surfactant, and an organic co-solvent. After the contacting step, the article is separated from the liquid dry cleaning composition. The method is preferably carried out at ambient temperature. The surfactant is preferably one that does not contain a CO2-philic group. The organic co-solvent is preferably an alkane and has a flash point above 140° F.