baber/WOPTO huggingface dataset:
Patent EP-1115884-A1 (EP)
Title: Methodes d'identification de plusieurs cibles primaires d'un medicament
Inventor: FRIEND STEPHEN H
IPC: C12Q1/68
Filed: 1999-09-22
Abstract: L'invention concerne des méthodes et des systèmes servant à caractériser l'effet de médicaments dans des cellules. Cette invention porte notamment sur des méthodes d'identification de plusieurs cibles primaires par le biais desquelles un médicament, un médicament candidat, ou un autre composé d'intérêt agit sur une cellule. Ainsi, ladite invention a également trait aux méthodes de mise au point de médicaments fondées sur lesdites méthodes d'identification de plusieurs cibles primaires d'un médicament. Les méthodes de cette invention consistent à: (i) mesurer les réactions de constituants cellulaires à des expositions graduées de la cellule à un médicament d'intérêt, (ii) identifier une «concentration d'inflexion» du médicament pour chaque constituant cellulaire mesuré, et (iii) identifier des «séries d'expression» de constituants cellulaires à partir de la distribution des concentrations d'inflexion du médicament. Chaque série d'expression correspond à une cible primaire particulière du médicament. Cette invention concerne également des systèmes informatiques qui identifient plusieurs cibles d'un médicament en exécutant les méthodes divulguées.
Patent EP-1115855-A1 (EP)
Inventor: CALDERONE RICHARD A
IPC: C12N9/12
Filed: 1999-09-23
Abstract: La présente invention concerne des acides nucléiques codant pour un régulateur de réaction, CaSsk1p, et leurs méthodes d'utilisation. L'invention concerne également la construction, la caractérisation et l'emploi d'un mutant Δcassk1 de C. albicans et ses procédés d'utilisation.
Patent EP-1102559-A1 (EP)
Inventor: DUNN TIMOTHY C
IPC: A61B5/103
Filed: 1999-09-27
Abstract: The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject.
Patent EP-1125129-A1 (EP)
Title: Composants de circuit fluidique bases sur la dynamique passive des fluides
Inventor: MCNEELY MICHAEL R
IPC: B01J19/00
Filed: 1999-10-13
Abstract: L'invention concerne des procédés, permettant de commander l'écoulement d'un fluide dans des microcanaux, au moyen de soupapes passives ou de mécanismes d'arrêt placés dans lesdits microcaneaux. Les soupapes passives agissent comme des barrières anti-pression qui empêchent l'écoulement d'une solution au-delà des mécanismes d'arrêt, jusqu'à ce qu'une force suffisante soit établie afin de vaincre la force de la barrière anti-pression. Une utilisation bien étudiée des mécanismes d'arrêt comme soupapes passives permet de réguler l'écoulement de fluides dans les microcanaux, de sorte que ces fluides peuvent se mélanger ou se diluer après leur introduction dans un canal unique, ou peuvent être séparés dans plusieurs canaux sans avoir besoin de pipettage. Il est possible de réguler l'écoulement dans les différents canaux, de sorte que plusieurs puits ou chambres jumelés peuvent se remplir avant l'écoulement du fluide au-delà de n'importe lequel des puits et des chambres jumelés. Ce type de remplissage permet que tous les puits ou chambres subissent des réactions en même temps. L'invention concerne également l'utilisation de conduits d'air permettant d'empêcher le piégeage d'air dans les microcanaux.
Patent EP-1137859-A1 (EP)
Inventor: ORLANDI MAURO
IPC: E04H12/08
Filed: 1999-12-07
Abstract: The pole consists of a plurality of portions (1, 3), each having a constant cross section similar to that of the other portions. The dimensions of the cross section of each portion are such that one end of the portion (3) can be inserted with minimum play into the end of an adjacent portion (1), and means (5, 5A, 5B) capable of forming an axial stop between two adjacent portions are provided.
Patent EP-1133518-A1 (EP)
Inventor: ORLOVSKI VLADISLAV
IPC: C07K5/075
Filed: 1999-11-18
Abstract: The synthesis of N-[N-(3,3-dimethylbutyl)-L-alpha-aspartyl]-L-phenylalanine 1-methyl ester via conversion under reducing conditions of novel imidazolidinone(s) is disclosed.
Patent EP-1141657-A1 (EP)
Title: Method and device for reading navigation data
Inventor: GOLISCH FRANK
IPC: G06F19/00
Filed: 1999-11-08
Abstract: Simplified navigation directions are provided when a navigation compact disk is not available in a shared compact disk reader. In a preferred arrangement, simplified navigation directions include heading to desired destination and/or distance to desired destination. An audio compact disk may be played while the simplified directions are provided. When a navigation compact disk is available in a shared compact disk reader, detailed directions may be calculated and provided.
Patent EP-1141090-A1 (EP)
Inventor: JOACHIMI DETLEV
IPC: C08G69/02
Filed: 1999-12-10
Abstract: A process for the production of polyamides is disclosed. In a first reaction step, suitable monomers such as caprolactam or an aliphatic aminocarboxylic acid are reacted with polyfunctional amines, which contain at least one secondary amino group, and/or with salts containing such amines and dicarboxylic acids. The reaction product is in a further process step undergoes solid phase post-condensation.
Patent EP-1152656-A1 (EP)
Inventor: SANDBERG JAN
IPC: B08B9/093
Filed: 1999-12-22
Abstract: The device relates to a method for the cleaning of animal stalls, which have a number of spaces that are to be cleaned by means of an automatic clean device. The method is characterized by the steps of (a) positioning the device in a parking position, in which the device can reach into and clean a first space, (b) cleaning of the first space through manual controlling of the device, (c) the repetition of steps (a) and (b) until all the spaces in the premises which are to be cleaned have been cleaned by the device, programming the device with the movements which were performed during the above-mentioned steps, by means of signals representing these movements which are supplied to a control unit, through registering the movements performed by storage of the steps in a memory which is provided in a control unit which is part of the device, and the use of the contents of the memory during the next cleaning of the same animal stall as a program for the control unit for the automatic controlling of the device.
Patent EP-1140127-A1 (EP)
Inventor: MAES LOUIS JULES ROGER MARIE
IPC: C07C69/00
Filed: 1999-12-15
Abstract: Saponins of formula (I), a stereoisomeric form thereof or a pharmaceutically acceptable addition salt thereof, wherein R1 to R12 have the meaning given in the description, can be isolated from plants of the family Myrsinaceae and used to decrease the infectiousness of and reduce the mortality associated with protozoan parasites of the genus Leishmania which are responsible for a group of conditions known as leishmaniases.
Patent EP-1050066-A1 (EP)
Inventor: SEIBOLD MICHAEL
IPC: H01J61/04
Filed: 1999-08-28
Abstract: A discharge lamp which can be operated by means of a dielectrically inhibited charge, comprising metal electrodes that are arranged on the wall of the discharge vessel and provided with at least one dielectric inhibiting layer that covers at least one part of said electrodes. According to the invention, the electrodes are also directly covered by a barrier layer that is especially made of a sintered glass ceramic material, i.e. the barrier layer is optionally and respectively arranged between the electrode and the dielectric inhibiting layer. This prevents the diffusion of metal ions from the electrode into the dielectric barrier layer and prevents them from having an undesirable effect on the properties thereof. This also prevents volatilization or sputtering in the electrode paths when the lamp is in operation.
Patent EP-1123254-A1 (EP)
Inventor: SLATER JOSEPH ARTHUR
IPC: B65B57/06
Filed: 1999-09-17
Abstract: L'invention concerne des systèmes (8), des procédés et des dispositifs de distribution de liquides. Selon un de ces procédés, on utilise une plaque (10) comportant une pluralité de puits (14), et un marqueur au moins, associé à certains puits au moins. On déplace la plaque et le marqueur par rapport à une pluralité d'éléments distributeurs de liquide, et on détecte la présence du marqueur au moyen d'un capteur disposé en un emplacement connu par rapport aux éléments distributeurs. La détection du marqueur indique que certains puits au moins sont alignés avec les éléments distributeurs. Ainsi, les éléments distributeurs distribuent le liquide dans les puits alignés, après détection de la présence du marqueur.
Patent FI-20175808-A1 (FI)
Title: Recovery of nutrients and energy from sewage sludge and animal manure
Inventor: NIEMINEN MATTI
IPC: C02F11/13
Filed: 2017-09-12
Abstract: According to an example aspect of the present invention, there is provided a method for recovering nutrients and energy from sewage sludge and animal manure in an efficient manner by combining unit operations of drying, thermal gasification and ammonia and phosphorus recovery. In addition, a tailored fertilizer is provided from the recovered ammonia and phosphorus.
Patent FI-20185959-A1 (FI)
Title: Binder composition and a liquid binder
Inventor: LEPISTÖ HARRI
IPC: C09J161/06
Filed: 2018-04-20
Abstract: According to an example aspect of the present invention, there is provided a binder composition suitable for the production of composite lignocellulose products, comprising an aldehyde based resin and a catalyst, combined into dry grains which are capable of being dissolved in water to provide a liquid binder.
Patent FI-20195002-A1 (FI)
Title: A method of using a machine-readable code for instructing camera for detecting and monitoring objects
Inventor: VALKONEN HANNU
IPC: H04N7/18
Filed: 2019-01-02
Abstract: The invention relates to a method, comprising capturing image data by at least one camera (13, 14) of a camera system (10), analysing the image data, detecting a machine readable code (12) comprising configuration data from the image data, and configuring the camera system (10) on the basis of the configuration data of the machine readable code (12). The invention further relates to a camera system (10) performing the method and to a computer program product.
Patent HK-1023063-A1 (HK)
Title: Process to obtain oestrogens from mare's urine
Inventor: BAN IVAN
IPC: A61K35/22
Filed: 2000-04-06
Abstract: Recovery of a phenolics-depleted natural mixture of conjugated oestrogens from the urine of pregnant mares comprises (a) providing a liquid urine (which comprises a urine freed from mucous and solids, a concentrate of the latter or a urine retentate obtained by membrane filtration) and treating it with a water-soluble base to give a pH of at least 12 and subsequently treating with aqueous acid to adjust the pH to 5-8.5; (b) contacting the urine with a hydrophobised silica gel to adsorb the conjugated oestrogens and separating the gel from the mixture; (c) washing the gel with an aqueous buffer adjusted to pH 5-7; and (d) eluting the oestrogens from the gel using a mixture of water and a water-miscible solvent selected from ethers, lower alcohols and lower aliphatic ketones, and optionally concentrating the eluate;
Patent HK-1024232-A1 (HK)
Title: Therapeutically active levorotatory and dextrorotatory 1-((4-chlorophenyl)phenylmethyl)piperazines
Inventor: COSSEMENT ERIC
IPC: A61P25/22
Filed: 2000-05-02
Abstract: The use of levorotatory or dextrorotatory enantiomers of 1-(4-chlorophenyl)phenylmethylpiperazine derivatives (V) or their salts in medicines for the treatment of allergies, is new.  The use of levorotatory or dextrorotatory enantiomers of 1-(4-chlorophenyl)phenylmethylpiperazine derivatives of formula (V) or their salts, in medicines for the treatment of allergies, is new:  R  =  H, (3-methylphenyl)methyl, (4-tert-butylphenyl)methyl, 2-(2-hydroxyethoxy)ethyl, 2-(2-(hydroxyethoxy)ethoxy)ethyl, 2-(carbamoylethoxy)ethyl, 2-(methoxycarbonylmethoxy)ethyl or 2-(carboxymethoxy)ethyl.
Patent HK-1035675-A1 (HK)
Title: Preparation for regenerating collagen
Inventor: DIETZ GEORG
IPC: A61L27/00
Filed: 2001-07-31
Abstract: The invention relates to a preparation containing calcium hydroxide, a dihydric or polyvalent alcohol, a fatty oil of vegetable or animal origin and possibly pharmaceutically compatible adjuvants. The invention also relates to the production of such a preparation, the use of such a preparation for the regeneration of collagen and the use of such a preparation for the production of a medicine which promotes the in vivo regeneration of collagen.
Patent HK-1041205-A1 (HK)
Title: Ligand for the c-kit receptor and methods of use thereof
Inventor: PETER BESMER
IPC: C12N5/0789
Filed: 2002-02-26
Abstract: A pharmaceutical composition which comprises the c-kit ligand (KL) purified by applicants or produced by applicants' recombinant methods in combination with other hematopoietic factors and a pharmaceutically acceptable carrier is provided as well as methods of treating patients which comprise administering to the patient the pharmaceutical composition of this invention. This invention provides combination therapies using c-kit ligand (KL) and a purified c-kit ligand (KL) polypeptide, or a soluble fragment thereof and other hematopoietic factors. It also provides methods and compositions for ex-vivo use of KL alone or in combination therapy. A mutated KL antagonist is also described. Such an antagonist may also be a small molecule. Antisense nucleic acids to KL as therapeutics are also described. Lastly, compositions and methods are described that take advantage of the role of KL in germ cells, mast cells and melanocytes.
Patent HK-1044094-A1 (HK)
Title: Position information informing method and mobile communication terminal
Inventor: YAMAMOTO HIROYUKI
IPC: H04W4/20
Filed: 2002-07-30
Abstract: Menu data supplied from an IP server 500 to a mobile station 101 is embedded with a location information substitution data string "NULLAREA" together with a URL of a particular IP server 500. The mobile station 101, upon detection of the location information substitution data string from a menu data selected by the user, determines whether location information can be transmitted to the IP server 500. In the case where the determination is that the transmission is permitted, the mobile station 101 detects its location information and, after substituting the location information for the location information substitution data string, transmits the data to the IP server 500. <IMAGE>
Patent HK-1062633-A1 (HK)
Title: Azoles as malonyl-coa decarboxylase inhibitors useful as metabolic modulators
Inventor: ARRHENIUS THOMAS
IPC: A61K31/425
Filed: 2004-06-16
Abstract: The present invention relates to methods of treatment of certain metabolic diseases, and to the use of compounds and their prodrugs, and/or pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds useful in treating such diseases. In particular, the invention relates to the use of compounds and compositions for treatment of cardiovascular diseases, diabetes, cancers, acidosis, and obesity through the inhibition of malonyl-CoA decarboxylase (MCD). These compounds have the following formulae: (I) and (II) Wherein Y, C, R1, R2, R6, and R7 are defined herein.
Patent HK-1087984-A1 (HK)
Title: Writing utensil
Inventor: NICOLAY HILMAR
IPC: B43K24/06
Filed: 2006-04-06
Abstract: The invention relates to a writing utensil comprising a one-piece or multi-piece sleeve which receives a writing insert that is retracted within the sleeve in an inoperative position while partially protruding from the sleeve in a writing position. The writing insert is moved between the inoperative position and the writing position by axially displacing a part of the writing utensil, which holds the writing insert, towards the sleeve. The aim of the invention is to create a writing utensil which is provided with a small number of parts while being inexpensive to produce and easy to handle. Said aim is achieved by the fact that the writing insert is positionally fixed relative to the sleeve at least in the writing position by means of a magnetic force that is effective between the elements of a magnetic system. Said magnetic system essentially encompasses at least one magnet and at least one counterpart that is attracted by the magnet/s. The elements thereof are components of the parts embodying the writing utensil, each magnet being a component of one of said parts while each counterpart of a magnet is a component of one of the other parts.
Patent HK-1092293-A1 (HK)
Title: Soft-decision decoding of multi-stage chain reaction codes
Inventor: SHOKROLLAHI M AMIN
IPC: H04L1/00
Filed: 2006-12-07
Abstract: A communications system includes an encoder that produces a plurality of redundant symbols. For a given key, an output symbol is generated from a combined set of symbols including the input symbols and the redundant symbols. The output symbols are generally independent of each other, and an effectively unbounded number of output symbols (subject to the resolution of the key used) can be generated, if needed. The output symbols are information additive such that a received output symbol is likely to provide additional information for decoding even when many symbols are already received. The output symbols are such that a collection of received output symbols can provide probabilistic information to support error correction. A decoder calculates check symbols from the output symbols received, wherein each check symbol is associated with one or more input symbols and redundant symbols For each received output symbol, the decoder updates a running total of estimated information content and, in one or more rounds, generates a probability distribution for each input symbol over all or some of the possible values of input symbols. This process may be repeated until, for all of the input symbols, one of the many possible values is much more probable than others, or the process may be repeated a predetermined number of rounds, or other criteria is met. The updating can take into account already decoded symbols, additional output symbols and the check symbols.
Patent HK-1095505-A1 (HK)
Title: Test device for analyzing body fluids
Inventor: HOENES JOACHIM
IPC: B01L99/00
Filed: 2007-03-12
Abstract: Test device comprises a test tape (16) having a functional section (40) that can be brought into a functional position by advancing the tape. An independent claim is also included for a tape cassette for the test device. Preferred Features: The functional section interacts with a measuring unit (18) in the functional position. The functional section has a calibrating field for calibrating the measuring unit. The functional section has a white, black, gray, colored or transparent calibrating field for an optical measuring unit. A comparator (42) is also provided for comparing a measured value determined on an unused test section (38) or functional section with a theoretical value.
Patent HK-1107378-A1 (HK)
Title: Method for production of a material web in particular a ribbon with a velvet edge and device for carrying out the method
Inventor: SPEICH FRANCISCO
IPC: D06H/
Filed: 2008-01-29
Abstract: The invention relates to a method for production of a material web in particular a ribbon with a velvet edge (6), wherein a material web (4) is separated by cutting the weft threads (18) with a cutting tool (16) along the warp threads (20, 20a, 20b) and extracting and removing the warp threads (20e) adjacent to the cutting edge. According to the invention, the velvet edge (6) and the device for production thereof may be improved, by arranging a deflector body (22, 24) after the cutting tool (16) to at least one side in the material web (4a, 4b) at a separation from the warp threads (20a) for extraction in order to separate the warp threads (20a) for extraction from the remaining warp threads (20, 20b).
Patent HK-1119386-A1 (HK)
Title: Tablet-type controlled-release preparation containing cinnarizine and dimenhydrinate for combating vertigo
Inventor: FRANCAS GERNOT
IPC: A61K/
Filed: 2008-06-19
Abstract: The invention describes a pharmaceutical composition of a slow-release preparation in the form of tablets for the treatment of vertigo of any genesis. A pharmaceutical composition is described that contains cinnarizine and dimenhydrinate, wherein the release of active ingredients is slowed down. For this purpose, the pharmaceutical composition additionally contains binding agent, slow-release agent and fillers.
Patent HK-1120836-A1 (HK)
Title: Fireable, low melting nickel-chrome alloy for manufacturing ceramic lined dental restorations
Inventor: ABEND ULRICH
IPC: A61K/
Filed: 2009-01-02
Abstract: Fireable alloy (I) to prepare dental restoration blended with ceramic material, comprises +- 37, preferably 18-23.5 wt.% of nickel-chromium; 8-16 wt.% of molybdenum and tungsten; 0.5-3.4, preferably 2.1-3.4 wt.% of silicon and 0.31-2.5 wt.% or 0-0.05 wt.% of boron; 0-0.9 wt.% of niobium; 0-0.5 wt.% of manganese; 0-0.02 wt.% of carbon; 0-30 wt.% of iron, cobalt and copper; 0-0.5 wt.% of aluminum, titanium, zirconium, hafnium, yttrium, lanthanum, cerium, other rare earth metals, calcium and strontium; 0-0.3 wt.% of beryllium; and 0-10 wt.% of other metal, metalloids and other ingredients. An independent claim is included for a ceramic blended dental restoration comprising a scaffold of (I); and a dental ceramic with a heat expansion coefficient of 12-14 [10 6>K ->1] at 25-500[deg] C, which is calcined on the scaffold.
Patent HK-1130422-A1 (HK)
Title: A new use of deferiprone
Inventor: SPINO MICHAEL M
IPC: A61P/
Filed: 2009-09-11
Abstract: A method of treating iron induced cardiac disease in a patient with iron overload, such as in thalassemia or the like comprising administering to the patient a therapeutically effective amount of deferiprone or a physiologically acceptable salt thereof sufficient to treat induced cardiac disease normally associated with iron overload.
Patent HK-1159455-A1 (HK)
Title: Oral care implement
Inventor: HOHLBEIN DOUGLAS J
IPC: A46B9/04
Filed: 2007-10-16
Abstract: An oral care implement with a handle includes a head with a releasable material (e.g., an oral medicament) and a tissue cleanser for cleaning the soft tissues and removing odor-causing bacteria from the mouth. In one arrangement, the releasable material is disposed on the surface of the tissue cleanser. In one arrangement, the releasable material is disposed behind the tissue cleanser. In one arrangement, the releasable material is incorporated in the composition of the tissue cleanser.
Patent HK-1204616-A1 (HK)
Title: Quinuclidin-4-ylmethyl 1h-indole-3-carboxylate derivatives as alpha 7 nicotinic acetylcholine receptor ligands 7--4- 1h--3-
Inventor: PFISTER JURG R
IPC: C07D/
Filed: 2015-06-01
Abstract: The present invention relates to compounds and formulations capable of affecting nicotinic acetylcholine receptors (nAChRs), for example, as modulators of specific nicotinic receptor subtypes (specifically, the alpha7 nAChR subtype). The present invention also relates to methods for treating a wide variety of conditions and disorders, particularly those associated with dysfunction of the central and autonomic nervous systems.
Patent HK-1002808-A1 (HK)
Title: Container for articles
Inventor: NEGELEN EMANUEL
IPC: B65D5/52
Filed: 1998-03-10
Abstract: PCT No. PCT/GB93/01481 Sec. 371 Date Mar. 13, 1995 Sec. 102(e) Date Mar. 13, 1995 PCT Filed Jul. 14, 1993 PCT Pub. No. WO94/02380 PCT Pub. Date Feb. 3, 1994There is provided a basket type container 11 having a handle portion 12 for carrying a plurality of bottles 14. The container 11 has side walls 18 and end panels 24, 25. There are also retention panels 15 extending between the side walls 18 and the handle portion 12 for holding the bottles in the container 11 and preventing removal. Lines of weakening may be provided to disable the retention panels 15 and allow access to the bottles 14.