Patent SG-11201906748P-A (SG)
Title: Microbial cells, methods of producing the same, and uses thereof
Inventor: DROUILLARD JAMES SCOTT
IPC: C12N1/04
Filed: 2018-01-31
Abstract: International Patent Classification: A23K 1/00 (2006.01) C12N 1/00 (2006.01) A23K 1/18 (2006.01) C12N 1/04 (2006.01) C12N 1/14 (2006.01) C12N 1/21 (2006.01) A61P 31/04 (2006.01) • Permeate Fluid (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 09 August 2018 (09.08.2018) WIP0 I PCT Iiiimmomiolollmonolomolomomulollooluovom (10) International Publication Number WO 2018/144653 Al (21) International Application Number: PCT/US2018/016321 (22) International Filing Date: 31 January 2018 (31.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/452,804 31 January 2017 (31.01.2017) US 62/452,816 31 January 2017 (31.01.2017) US 62/510,723 24 May 2017 (24.05.2017) US (71) Applicants: KANSAS STATE UNIVERSITY RESEARCH FOUNDATION [US/US]; 2005 Research Park Circle, Suite 105, Manhattan, Kansas 66502 (US). MS BIOTECH, INC. [US/US]; 2489 W. Main Street, Littleton, Colorado 80120 (US). (72) Inventors: DROUILLARD, James Scott; 133 Call Hall, Manhattan, Kansas 66506 (US). APERCE, Celine Caro- line; 1300 Kaw Valley Road, Wamego, Kansas 66547 (US). HERREN, Gina Rae; 1300 Kaw Valley Road, Wamego, Kansas 66547 (US). ELLERMAN, Tara Jo; 119 Call Hall, Manhattan, Kansas 66506 (US). SCALETTI, Ciana Marie; 116 Weber Hall, Manhattan, Kansas 66506 (US). VAN JORDAN, Katherine; 214 Weber Hall, Manhat- tan, Kansas 66506 (US). LATTIMER, James Morris; 132 Weber Hall, Manhattan, Kansas 66506 (US). BEYER, Scott; 130 Call Hall, Manhattan, Kansas 66506 (US). UWI- TUZE, Solange; Regional Universities Forum for Capacity Building in Agriculture (RUFORUM), Plot 151/155 Garden Hill, Makerere, University Main Campus, P.O. Box 16811 Wandegeya, Kampala (UG). DOUTHIT, Teresa Lea; 129 Weber Hall, Manhattan, Kansas 66506 (US). GUNKEL, Christina Denise; 43779 Callaway Rd, Broken Bow, Ne- braska 68822 (US). (74) Agent: LONGSWORTH, Gaby L. et al.; STERNE, KESSLER, GOLDSTEIN & FOX P.L.L.C., 1100 New York Avenue, NW, Washington, District of Columbia 20005 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (54) Title: MICROBIAL CELLS, METHODS OF PRODUCING THE SAME, AND USES THEREOF Process Vessel • Permeate Side Tang tial Flow Filtration i odule Retentate Side Retentate Loop Recirculation 1-1 Pump FIG. 3 71' 71' 1-1 1 -1 (57) : The present invention relates to microbial cells, including but not limited to aerobic bacteria cells and anaerobic bacteria © cells, as well as yeast cells, and methods for producing the cells, feed additives and compositions comprising the cells, and uses involving administration of the cells to animals. C [Continued on next page] WO 2018/144653 Al MIDEDIM011010EIREEM0M0111HOEH0111101111111111101111111111 UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))