baber/WOPTO huggingface dataset:
Patent JP-3683798-B2 (JP)
IPC: A61K35/12
Filed: 2000-10-18
Granted: 2005-08-17
Abstract: A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate, comprising the interstitial introduction of an isolated polynucleotide into a tissue of the vertebrate where the polynucleotide is taken up by the cells of the tissue and exerts a therapeutic effect on the vertebrate. The method can be used to deliver a therapeutic polypeptide to the cells of the vertebrate, to provide an immune response upon in vivo translation of the polynucleotide, to deliver antisense polynucleotides, to deliver receptors to the cells of the vertebrate, or to provide transitory gene therapy.
Patent JP-3330369-B2 (JP)
IPC: A61B8/08
Filed: 2000-12-15
Granted: 2002-09-30
Abstract: PROBLEM TO BE SOLVED: To provide an ultrasonic bone evaluation device with improved measuring reliability. SOLUTION: Bottom surface frames 46a, b pressurizes the deformable biological contact surfaces 44a, b of an acoustic matching material housing parts 42a, b to a biological surface. The parts 42a, b have side wall parts 43a, b in the state of bellows, have oscillator fitting parts fitted with ultrasonic vibrator transducers 24 to be scanned by a scanning mechanism and the surfaces 44a, b and store acoustic matching materials in their internal spaces.  Consequently, when the transducers 24 are scanned in an optional direction by a scanning mechanism, the side wall pars 43a, b of the acoustic matching material having parts 42a, b are deformed in accordance with the movement of the transducer 24 to smoothen the scanning and absorbs the movement to keep adherence with respect to the biological surface of the surfaces 44a, b and to constantly fill an ultrasonic propagation path with the acoustic matching materials.
Patent JP-4383652-B2 (JP)
IPC: A61L15/44
Filed: 1998-09-01
Granted: 2009-12-16
Abstract: A wound dressing is formed from a covering release layer, a dressing layer, an indicator layer, a transparent or translucent indicator bonding layer and a transparent or translucent outer covering. The indicator layer contains a dye which changes colour on contact with water. When the dressing layer becomes saturated, water permeates the indicator layer and triggers a colour change. The colour change is visible through the indicator bonding layer and outer covering and shows a carer that the dressing needs to be replaced.
Patent JP-4533534-B2 (JP)
IPC: A61P37/04
Filed: 1999-06-18
Granted: 2010-09-01
Abstract: New pyrimidine or pyridine based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alone, or in combination with other pharmacologically active agents in the treatment of disorders mediated by GSK3 activity, such as in the treatment of diabetes, Alzheimer's disease and other neurodegenerative disorders, obesity, atherosclerotic cardiovascular disease, essential hypertension, polycystic ovary syndrome, syndrome X, ischemia, traumatic brain injury, bipolar disorder, immunodeficiency or cancer.
Patent JP-4672866-B2 (JP)
IPC: C07K14/72
Filed: 1999-10-12
Granted: 2011-04-20
Abstract: Disclosed herein are constitutively activated, non-endogenous versions of endogenous human G protein-coupled receptors comprising (a) the following amino acid sequence region (C-terminus to N-terminus orientation) and/or (b) the following nucleic acid sequence region (3' to 5' orientation) transversing the transmembrane-6 (TM6) and intracellular loop-3 (IC3) regions of the GPCR: (a) P<SUP>1 </SUP>AA<SUB>15</SUB>X and/or (b) p<SUP>codon </SUP>(AA-codon)<SUB>15 </SUB>X<SUB>codon</SUB>, respectively. In a most preferred embodiment, P<SUP>1 </SUP>and P<SUP>codon </SUP>are endogenous proline and an endogenous nucleic acid encoding region encoding proline, respectively, located within TM6 of the non-endogenous GPCR; AA<SUB>15 </SUB>and (AA-codon)<SUB>15 </SUB>are 15 endogenous amino acid residues and 15 codons encoding endogenous amino acid residues, respectively; and X and X<SUB>codon </SUB>are non-endogenous lysine and a non-endogenous nucleic acid encoding region encoding lysine, respectively, located within IC3 of the non-endogenous GPCR. Because it is most preferred that the non-endogenous human GPCRs which incorporate these mutations are incorporated into mammalian cells and utilized for the screening of candidate compounds, the non-endogenous human GPCR incorporating the mutation need not be purified and isolated per se (i.e., these are incorporated within the cellular membrane of a mammalian cell), although such purified and isolated non-endogenous human GPCRs are well within the purview of this disclosure.
Patent JP-4636693-B2 (JP)
IPC: D01F6/18
Filed: 2000-03-28
Granted: 2011-02-23
Abstract: The present invention discloses novel fibers for use as secondary reinforcement materials in cementitious composites, which fibers are effective in preventing cracking far better than prior art fibers. Also disclosed are methods of producing the fibers and methods for producing cementitious composite containing the fibers.
Patent JP-3556914-B2 (JP)
IPC: F25J3/04
Filed: 2001-03-01
Granted: 2004-08-25
Abstract: Oxygen and nitrogen are produced by cryogenic separation in which at least a portion (112) of feed air is introduced to a first (130) of at least three distillation columns (130, 164, 166). An oxygen-lean stream (132) from or near the top of the first column (130) is at least partially condensed in a reboiler-condenser (141; 135) of the second or third column (164; 166) to provide reflux for the first column. Oxygen-enriched liquid (168) from the bottom of the first column (130) is fed to the second or third column (164; 166). Nitrogen enriched liquid (154), which can be a portion (150) of the condensed oxygen-lean stream from the first column (130), is fed to the second column(164). Oxygen-enriched liquid bottoms (160) from the second column (164) is fed to the third column (166) and nitrogen-rich vapour overheads (194; 182) are withdrawn from the second and third columns (164; 166). A liquid oxygen-rich stream (173) from the third column (130) is elevated in pressure (173) and warmed (110), at least in part, by indirect heat exchange with a pressurized stream (116) having a nitrogen content greater than or equal to that in the feed air. The pressurized stream is cooled without being subjected to distillation and is fed to any one or combination of the three columns (130, 164, 166).
Patent JP-3979804-B2 (JP)
IPC: B08B3/04
Filed: 2001-08-17
Granted: 2007-09-19
Abstract: PROBLEM TO BE SOLVED: To provide a substrate treatment apparatus which can treat a substrate with satisfactory efficiency, by reducing the dead time made by a vacancy in the treatment or the conveyance of the substrate in a treatment part or a conveyance mechanism. SOLUTION: A gripping part 4b which grips the side of a carrier C housing a plurality of untreated or treated substrate Ws and which conveys two carriers Cs is installed. A carrier conveyance mechanism 4 is constituted in such a way that it is provided with the gripping part 4b, and that the two carriers Cs are simultaneously conveyed. As a result, the dead time made by the vacancy in the treatment or the conveyance of the substrates Ws in respective treatment parts 13 to 15 or the conveyance mechanism is reduced, and the substrate Ws can be treated with satisfactory efficiency.
Patent JP-3785348-B2 (JP)
IPC: G03F7/00
Filed: 2001-11-08
Granted: 2006-06-14
Abstract: PROBLEM TO BE SOLVED: To provide a lithographic printing plate master which has excellent sensitivity, stain resistance and plate wear resistance and in which a coating fault does not occur at the other end side of a gripper of an adjacent part of a solid image part to a non-image part in printing or the like by an offset rotary printer and to provide a support for the lithographic printing plate. SOLUTION: The support for the lithographic printing plate is obtained by specific surface treating an aluminum plate. The support has a surface area difference obtained by dividing the real area obtained by using an interatomic force microscope (AFM) by an apparent area for the surface of the support of 10 to 90%, an area ratio of the part having an inclining degree of 30 deg. obtained by using the AFM of 75% or less, and an arithmetic mean roughness after the component of the wavelength of 0.1 to 2 μm is extracted from a measured sectional curve obtained by using the AFM of 0.25 μm. The lithographic printing plate master comprises an image recording layer provided on the support for the lithographic printing plate.
Patent JP-3630305-B2 (JP)
IPC: H03H3/02
Filed: 2000-09-28
Granted: 2005-03-16
Abstract: An acoustic mirror is described which is formed of at least one first insulating layer, a first metal layer disposed thereon, a second insulating layer disposed thereon and a second metal layer disposed thereon. An auxiliary layer is produced on the first insulating layer whereby a recess extending as far as the first insulating layer is created therein. The first metal layer is substantially deposited and removed by chemical/mechanical polishing until the parts of the first metal layer disposed outside the recess are no longer present. The second metal layer is also produced in a recess with the aid of chemical/mechanical polishing. More than two insulating layers and two metal layers can be provided. The first metal layer and the second metal layer can be produced in the same recess.
Patent JP-4733327-B2 (JP)
IPC: H01L21/60
Filed: 2000-10-06
Granted: 2011-07-27
Abstract: The invention relates to a method for production of electrical units comprising chips (15) with contact elements (18), whereby said contact elements are suitable for making electrically conductive connections with the contact terminals (3) of external electrical components (6). Said contact element connections with the chips are made before said chips are released from the grouping into rows (26) and columns (27) as defined on the wafer (17). Said contact element comprises a metallised plastic (16) or metallic foil to be brought into contact with the chips.
Patent JP-4041909-B2 (JP)
IPC: A61B17/58
Filed: 2000-02-03
Granted: 2008-02-06
Abstract: The invention relates to medicine, in particular to spinal surgery and is used for curing spinal diseases and injuries in specialized departments of vertebrology and neurosurgery. The inventive device comprises not more than nine fixing units (46, 47, 48, 49, 62, 63, 76, 77, 78). Each unit bears two fixing elements fastened to it (109-126) which are embodied in the form of a threaded stem, the working end of which (180) are implanted in roots of vertebra arches (Th 8, Th7, Th6, Th10, Th11, Th12, L2, L3, L4) angularly at 35-45 DEG to the sagittal plane of the vertebra. The fixing units are connected to each other in groups of three with the aid of threaded ties (50, 51, 52, 64, 65, 66, 79, 80, 81), thereby forming support units (1, 2, 3). Two of the units are side units (1,3) and one is intermediate unit (2). The intermediate unit is connected to the side support units so that it can move with the aid of the connecting hinge junctions (174, 175, 176, 177, 178, 179). Dosed displacement is performed by means of moving distraction nuts (10-33). Displacement of noninvolved vertebrae is carried out until a normal correction of the spinal column occurs and ostial and ostial -fibrotic blocks are built up in the area of discotomy of vertebrae Th8 and Th9. <IMAGE>
Patent JP-4965043-B2 (JP)
IPC: A23L33/00
Filed: 2001-02-16
Granted: 2012-07-04
Abstract: In a pharmaceutical or dietetic preparation (A) for reducing and/or blocking the adhesion of pathogenic agents and organisms to eukaryotic cells (especially mammalian cells), containing carbohydrate(s) (I) having terminal uronic acid units, 10-100 (preferably 10-50) % of the terminal uronic acid units of (I) contain a double bond. An independent claim is included for the use of (I) (as described above) for reducing and/or blocking the adhesion of pathogenic agents and organisms to eukaryotic cells. ACTIVITY : Antibacterial; antifungal; virucide; antidote. MECHANISM OF ACTION : Antiadhesive.
Patent JP-4195222-B2 (JP)
IPC: C30B29/12
Filed: 2001-03-02
Granted: 2008-12-10
Abstract: Device for growing large volume single crystals comprises a housing (10) in which a melt crucible (20) with side walls (22), a base (24), a top opening (26) facing the base and optionally a lid (28) are located; and at least one heating element (50, 50'). At least one heating element is arranged on the side walls of the melt crucible (20) to prevent lateral radial heat flow. An independent claim is also included for a process for growing large volume single crystals using the above device. Preferred Features: The elements arranged on the side walls prevent lateral heat flow so that a planar solid/liquid phase boundary surface is formed during crystal growth which has a bending radius of at least 1 m. The base of the crucible has a conical shape.
Patent JP-3776844-B2 (JP)
IPC: G02F1/13363
Filed: 2002-06-28
Granted: 2006-05-17
Abstract: PROBLEM TO BE SOLVED: To improve the visual angle characteristic in a direction desired by a user by freely arranging the axes of polarization of two polarizing plates fixed heretofore in a 45 deg. direction of a liquid crystal display device of an OCB system regardless of the optical axis direction of a liquid crystal layer bendingly aligned. SOLUTION: The polarizing plates 206 and 207 and λ/4 wavelength plates 208 and 209 are attached to first and second substrates 202 and 203 of a liquid crystal panel subjected to the bend orientation by including the transmission axes of the polarizing plates and the optical axes of the λ/4 wavelength plates in such a manner that the circularly polarized light rays reverse from each other are obtained. At this time, incident light is converted to the circularly polarized light and is made incident on the liquid crystal layer and does not therefore depend in the polarizing plate axial directions of the polarizing plates and the maximum value of the intensity of the emitted light is constant.  Thus, the optical axes of the liquid crystal layer can be arranged in free directions without receiving restrictions except that the transmission axes of the first and second polarizing plates are interested orthogonally with each other while the optical axes are held fixed in the horizontal direction desirable for the stability of the bend orientation, and the visual angle of the desired direction concentration can be made wider.
Patent JP-4284051-B2 (JP)
IPC: C02F3/02
Filed: 2002-09-06
Granted: 2009-06-24
Abstract: The present invention relates to a three-phase separator (33) for separating off from a fluid gas and particles contained therein, comprising at least one pair of two gas collection caps (1, 2) extending in a horizontal longitudinal direction (L) and each having a plate section (3, 4). The plate sections converge in the downward direction. At the bottom ends the plate sections leave an inlet passage (7), elongated in the longitudinal direction, for the fluid containing particles and an outlet passage (8), elongated in the longitudinal direction, for settled particles. A discharge opening (9) for fluid, opening into the settling chamber, is provided at a level higher than the inlet and outlet passages. The inlet passage (7) and the outlet passage (8) are located in the extension of one another, viewed in the longitudinal direction. The surface area of the inlet passage is preferably greater than the surface area of the outlet passage. The discharge opening is provided level with or beyond the outlet passage. <IMAGE>
Patent JP-4135499-B2 (JP)
IPC: H04W4/029
Filed: 2002-12-27
Granted: 2008-08-20
Abstract: In one of multiple mobile communication networks, a serving node responsible for locating mobile terminals is responsive to a registration request from a mobile terminal for storing the serving node identity in a home location database to which the mobile terminal is subscribed. In response to a location request message from client terminal requesting the location of a target mobile terminal, a serving node identity is retrieved from the home location database of the target mobile terminal. The serving node identity represents the current location of the target mobile terminal. If the current location area is within the coverage area of location-based service provided by the client terminal, the location request message is forwarded to a serving node identified by the retrieved serving node identity. Otherwise, an error message is transmitted to the client terminal to indicate that the target mobile terminal is roaming outside of the coverage area.
Patent JP-5174312-B2 (JP)
IPC: C07K1/113
Filed: 2001-08-18
Granted: 2013-04-03
Abstract: The invention relates to a method for solubilising and purifying recombinant proteins which are expressed in bacterial host cells and are deposited as insoluble aggregates (inclusion bodies). The purification is based on conversion of the inclusion bodies into soluble forms using organic denaturing reagents and using chromatographic methods. Inorganic, alkaline, salt-containing eluents are selected here which, after purification is complete, enable the recombinant proteins, after neutralisation, to be made available in a form which can be employed directly for medical use and is physiologically acceptable. The method is particularly suitable for purifying allergens and allergen fragments.
Patent JP-4168327-B2 (JP)
IPC: H03F3/21
Filed: 2001-12-05
Granted: 2008-10-22
Abstract: A power amplifier circuit includes an amplifying transistor and a dc bias circuit for biasing the amplifying transistor to obtain a conduction angle of less than about 180°. The dc bias circuit includes a dynamic biasing circuit for decreasing the dc bias signal provided to the amplifying transistor as the input signal to the power amplifier circuit increases. This configuration permits the amplifier circuit to operate as a linearized Class C amplifier, having a substantially linear input-output relationship similar to that of a Class B amplifier, but with increased operating efficiency.
Patent JP-4056882-B2 (JP)
IPC: B01D63/16
Filed: 2002-01-10
Granted: 2008-03-05
Abstract: The invention is directed to a centrifugation bowl with a rotating core. The centrifugation bowl includes a rotating bowl body which defines a primary separation chamber. The core, which is generally cylindrically shaped and is disposed within the bowl body, defines a secondary separation chamber. A stationary header assembly may be mounted on top of the bowl body through a rotating seal. The stationary header assembly includes an inlet port for receiving whole blood and an outlet port from which one or more blood components are withdrawn. The inlet port is in fluid communication with a feed tube that extends into the primary separation chamber. The outlet port is in fluid communication with an effluent tube that extends into the bowl body. The effluent tube includes an entryway at a first radial position relative to a central, rotating axis of the bowl. The core is arranged at a second radial position that is outboard from the entryway to the effluent tube and includes one or more core passageways for providing fluid communication between the primary and secondary separation chambers. A sealed region is formed at the upper edge of the core relative to its attachment point to the bowl body. Also provided is a method for recovering a whole blood fraction from a donor using the core of the present invention.
Patent JP-4822656-B2 (JP)
IPC: H04N5/445
Filed: 2003-01-29
Granted: 2011-11-24
Abstract: The invention relates to a process for selecting services in a television system using graphical indications displayed on a screen. The invention comprises in particular the steps of:   (a) determining a first list (30) of services, the first list being a subset of a second list; (b) displaying at least a part of the first list, ordered according to a predetermined criterion; (c) selecting a service present in the second list, but not in the first list; (d) displaying a visual indicator (39) marking the relative location, according to the predetermined criterion, of the selected service in the first list (30).   The invention also relates to the terminal for the implementation of the process. <IMAGE>
Patent JP-4065845-B2 (JP)
IPC: F04B15/02
Filed: 2002-11-02
Granted: 2008-03-26
Abstract: The invention relates to a material feeding container for two-cylinder thick matter pumps. The material feeding container ( 24 ) has a material supply opening ( 30 ) oriented upward, two feed cylinder openings ( 34 ) arranged in the front wall ( 36 ) of the container and a transfer tube having the shape of an S-tube ( 42 ), which is arranged inside the container with its input end ( 48 ) swiveling in an alternating manner in front of the feed cylinder openings ( 34 ) and mounted on the output side in a feed-through opening ( 46 ) of the rear wall ( 38 ) of the container that is arranged above the feed cylinder openings. A pressure pipe ( 40 ) is connected to the outer side of the rear wall ( 38 ) of the container, the output side ( 44 ) of the S-pipe ( 42 ) leading into said pressure pipe. According to the invention, a maintenance opening ( 56 ) is arranged on the rear wall ( 38 ), which is formed by an opening defined by a peripheral edge ( 58 ). The maintenance opening ( 56 ) can be closed with a cover plate ( 60 ), which has a top cover plate part ( 64 ) that is oriented perpendicular to the swiveling axis ( 50 ) of the S-pipe ( 42 ) and includes the feed-through opening ( 46 ) for the S-pipe ( 42 ) and a bottom cover plate part ( 68 ) that forms an inclined bottom part and that is connected to said top part substantially parallel to an S-pipe segment ( 66 ) extending obliquely downward.
Patent JP-4797182-B2 (JP)
IPC: B05B15/52
Filed: 2002-11-28
Granted: 2011-10-19
Abstract: In a method for cleaning a material jet spray head having outside material jet spray cycles, an absorbent member and a wiper are positioned so that at least a section of the absorbent member is interposed between the wiper member and a material outlet device. The absorbent member and the wiper member thus form a cleaning assembly. Relative displacement between the cleaning assembly and the material outlet device occurs along a cleaning plane substantially perpendicular to the elevation direction so that the wiper member scrapes the material outlet device substantially simultaneously with absorption by the absorbent member.
Patent JP-4031436-B2 (JP)
IPC: A47L9/02
Filed: 2002-11-15
Granted: 2008-01-09
Abstract: The invention provides a cleaner head ( 50;90;130;180 ) for a vacuum cleaner comprising a housing ( 52;92;132;182 ), a suction opening ( 60;100;142;184 ) in a face ( 58;96;136;186 ) of the housing which is intended to face a floor surface, a suction passage ( 110;146 ) for conducting dirt-laden air from the suction opening ( 60;100;142;184 ) through the cleaner head to an outlet thereof, a bleed air inlet ( 200 ) arranged in the housing and closed by a bleed valve ( 76;124;166;198 ) which is openable to allow air to be bled into the suction passage via the bleed air inlet. The cleaner head further comprises a force-transmitting member ( 68 122;152;194;232 ) connected to, or adapted to be connected to, a handle ( 18;48 ) by means of which the cleaner head is, in use, maneuvered across the floor surface, and the force-transmitting member ( 68;122;152;194;232 ) is connected to the housing by a connection allowing relative movement between the force-transmitting member and the housing.
Patent JP-3927184-B2 (JP)
IPC: B23Q1/26
Filed: 2004-02-26
Granted: 2007-06-06
Abstract: The guide rail (1) has at least one rail element (2) with a guide track (3) for rolling bodies. The rail element is connected to or against a plastic body (4), which forms the base body of the guide rail. The rail element is connected to a metal carrier mounting (5), which is at least partly embedded in the material of the plastic body.