baber/WOPTO huggingface dataset:
Patent EP-1019057-B1 (EP)
Inventor: MCDONNELL DONALD P
IPC: A61K45/00
Filed: 1998-08-14
Granted: 2008-10-15
Abstract: The present invention relates, in general, to the treatment of estrogen-dependent diseases and disorders and, in particular, to a method of treating estrogen-dependent cancers, particularly breast cancer, with antiestrogens.
Patent EP-1015815-B1 (EP)
Inventor: DOUCET MICHEL
IPC: F23Q2/28
Filed: 1998-09-01
Granted: 2005-11-23
Abstract: A lighter of the disposable type, ignition of which requires depression of an actuator that is resistant to the manipulations of unintended users. The lighter is normally maintained in a position that prevents depression of the actuator through the incorporation of a mechanism that increases the difficulty of operation. The safety mechanism requires displacement in two directions in order to allow full depression of the actuator and activation of an ignition means. When the mechanism is so displaced through the application of force by a user, it cannot remain displaced without continuous application of such force and will return to the normal, blocking, position when the force is removed.
Patent EP-1076734-B1 (EP)
Inventor: LAAKSO TAUNO
IPC: D21D5/02
Filed: 1998-11-17
Granted: 2004-02-11
Abstract: Apparatus is disclosed for screening fiber suspensions including a housing, an annular screen disposed within the housing, a rotor disposed within the annular screen for rotating relative to the annular screen, pulsation wings disposed between the outer surface of the rotor and the annular screen for relative rotation with the rotor, an inlet for the fiber suspension to feed the fiber suspension to one end of the screening zone, an accept outlet for a portion of the fiber suspension which passes through the annular screen, a reject outlet for a portion of the fiber suspension which does not pass through the annular screen, and a dilution liquid nozzle for supplying a dilution liquid to the screening zone between the rotor and the annular screen, the dilution liquid nozzle disposed proximate to the reject outlet and directing the dilution liquid into the screening zone along the outer surface of the rotor.
Patent EP-0964118-B1 (EP)
Inventor: EFFERTZ ERICH
IPC: E05B15/02
Filed: 1999-05-28
Granted: 2004-05-06
Abstract: An elongated base element (10) in one-piece is fixed to the door frame (14,28) by fixtures (18,26). A lock plate attachment (24) is detachably connected to the base element. The sheet-metal, U-shaped metal plate unit grips over the surface of the door frame when the base element is in place. The preferably glass fibre reinforced injection moulded plastics base element has at least one integral bar-section (12).
Patent EP-1004372-B1 (EP)
Inventor: WUNDERLICH HORST
IPC: B21K21/14
Filed: 1999-08-27
Granted: 2004-04-14
Abstract: A process for production of a tube profile element having a swaged closed head end includes the steps of chamfering an unswaged end of a tube profile element having a first diameter to provide a chamfered end on the tube profile element having a chamfer angle of less than 45° relative to a longitudinal axis of the end portion of the tube profile element, supporting the tube profile element in a retaining tool such that an end portion of the tube profile element having the unswaged chamfered end thereon extends beyond the retaining tool, providing a swage tool having a negative die capable of swaging the end portion of the tube into a swaged closed head end having a maximum second diameter larger the first diameter of the unswaged end of the tube, and moving the swage tool toward the end portion of the tube and swaging the unswaged chamfered end of the tube, by the negative die of the swage tool, into the swaged closed head end of the tube profile element. A muffler suspension made by the process includes a tube profile element of a first diameter and with a hollow interior, the tube profile element having a main body portion and opposite end portions. The main body portion has at least one bend formed therein. One of the opposite end portions has a swaged closed head end with a maximum second diameter larger the first diameter of the tube profile element and a fluid-tight configuration. The other of the opposite end portions has a fluid-tight configuration.
Patent EP-0982398-B1 (EP)
Inventor: TSIEN ROGER Y
IPC: C12Q1/68
Filed: 1996-03-20
Granted: 2003-11-05
Abstract: Substrates for  beta -lactamase of general formula (I) in which one of X and Y is a fluorescent donor moiety and the other is a quencher (which may or may not re-emit); R' is selected from the group consisting of H, lower (i.e. alkyl of 1 to about 5 carbon atoms) and (CH2)nOH, in which n is 0 or an integer from 1 to 5; R" is selected from the group consisting of H, physiologically acceptable metal and ammonium cations, - CHR<2>OCO(CH2)nCH3, -CHR<2>OCOC(CH3)3, acylthiomethyl, acyloxy-alpha-benzyl, delta-butyrolactonyl, methoxycarbonyloxymethyl, phenyl, methylsulphinylmethyl, beta-morpholinoethyl, dialkylaminoethyl, acyloxyalkyl, dialkylaminocarbonyloxymethyl and aliphatic, in which R<2> is selected from the group consisting of H and lower alkyl; A is selected from the group consisting of S, O, SO, SO2 and CH2; and Z' and Z" are linkers for the fluorescent donor and quencher moieties. Methods of assaying  beta -lactamase activity and monitoring expression in systems using  beta -lactamase as a reporter gene also are disclosed. <IMAGE> <IMAGE>
Patent EP-0998921-B1 (EP)
Inventor: TATARA MITSUTOSHI
IPC: A61J3/10
Filed: 1999-01-15
Granted: 2007-07-04
Abstract: A method and an apparatus are adapted to manufacture a tablet capable of quickly disintegration in the oral cavity that has a sufficiently large porosity and can be disintegrated in the oral cavity in a very short period of time, typically between 3 and 5 seconds. A tablet manufactured by means of such a method and such an apparatus also constitutes part of the present invention. The method for manufacturing a tablet capable of quickly disintegration in the oral cavity comprises steps of punching a tablet out of a pharmaceutical composition containing one or more than one medicinal agents and one or more than one water-soluble saccharides under pressure between 0.20 and 0.01 t/c m<2> and shaping the tablet by moisturizing and drying it, while transferring it without causing it to drop, said tablet having a porosity between 20 and 40%. <IMAGE>
Patent EP-1048608-B1 (EP)
Inventor: ZACCHE VANNI
IPC: B67C7/00
Filed: 1999-04-29
Granted: 2007-10-03
Abstract: The present invention relates to a continuous method and associated apparatus for the sterilization of drinks contained in bottles of plastics material, in particular in bottles of polyethylene terephthalate (PET). In particular, the present invention relates to an apparatus for the continuous sterilization of bottled drinks, of the rotary or linear type, comprising a plurality of sterilization devices (10) arranged along the operating line of the apparatus, each of the sterilization devices (10) being fashioned to contain a bottle (6) to be sterilized. The sterilization device (10) is preferably a device for the generation of high hydrostatic pressure. <IMAGE>
Patent EP-0962946-B1 (EP)
Inventor: REISCHER WILHELM
IPC: H01F17/02
Filed: 1999-04-28
Granted: 2004-08-11
Abstract: The coil has a connecting wire (6) from each of the upper and lower ends of the coil winding. The wires are fed down parallel to the coil axis and their ends protrude beyond the lower end of the coil. The connecting wire for the upper end of the coil is fed down through the coil interior, essentially along the coil axis.
Patent EP-1047360-B1 (EP)
Inventor: KAY DENNIS M
IPC: A61F5/44
Filed: 1999-01-15
Granted: 2004-10-13
Abstract: A two-piece external incontinence device includes a first member, which attaches comfortably and reliably to the urethral meatus of a patient, and a second member. The first member may be secured to the patient's parameatal area by suitable medical grade adhesives. The second member has a first end, which is dimensioned to be mated with the first member, and a second end, which is dimensioned to be mated with a standard urinary drainage tube or a straight connector or other medical apparatus. Mating of the first member and the second member should be leak-free and reliable, but should insure that, when excessive force is applied by pulling on the standard urinary drainage tube, the first and second members separate to eliminate transference of the force to the patient. These mating pieces also allow intermittent internal catheterization without the loss of the parameatal seal.
Patent EP-1051347-B1 (EP)
Inventor: SCHMID EMIL
IPC: B66B9/02
Filed: 1999-02-01
Granted: 2002-12-04
Abstract: The invention relates to a method and device for transporting people, preferably including bicycles and/or wheel chairs, and/or passenger cars and/or cargo trucks and/or for transporting objects and/or material along a travel way. The invention comprises at least one curved traveling section, preferably at least one essentially vertical traveling section, and preferably at least one essentially horizontal or sloping traveling section. The invention is especially provided for bypassing travel ways at a height which does not obstruct traffic. The invention uses a transporting unit, especially in the form of a cabin (21) and/or of a transporting platform which can continuously travel throughout on stationary rails (70, 71, 72, 73, 74) which extend continuously and throughout along the travel way. The transporting unit can travel at a high traveling velocity in a to-and-fro manner between a first station (1, 2) located on one side of the travel ways which are to be bypassed and a second station (1, 2) located on the other side of the travel ways.
Patent EP-1066060-B1 (EP)
Inventor: MOSCA JOSEPH D
IPC: A61K39/00
Filed: 1999-03-12
Granted: 2003-08-13
Abstract: The present invention provides a method to modulate immune responses using antigen presenting human mesenchymal stem cells to induce specific T cell anergy. The present invention also provides a method to modulate immune responses using human mesenchymal stem cells as a platform to express molecules which will induce T cell anergy.
Patent EP-1144932-B1 (EP)
Inventor: CHEN MICHAEL M
IPC: F28D19/04
Filed: 1999-05-27
Granted: 2004-03-31
Abstract: The thermal performance of the heat transfer element assemblies for rotary regenerative air preheaters is optimized to provide a desired level of heat transfer and pressure drop with a reduced volume and weight. The heat transfer plates in the assemblies have notches for maintaining plate spacing and oblique undulations between the notches. The undulations on adjacent plates extend at opposite oblique angles. The ratio of the openings of the undulations to the openings of the notches is greater than 0.3 and less than 0.5. The pitch (spacing) of the notches is greater than two inches and the angle of the undulations with respect to the notches is greater than 20 DEG  and less than 40 DEG .
Patent EP-1092131-B1 (EP)
Inventor: GRAY LARRY B
IPC: A61M1/14
Filed: 1999-06-25
Granted: 2005-09-07
Abstract: A method and system for determining when a fluid has stopped flowing within a line. The pressure variation in a second fluid, separated from the first by a pumping membrane, is measured in response to energy applied in a time-varying manner to the second fluid. From the response of the second fluid to the applied energy, it is determined whether the first fluid has stopped flowing.
Patent EP-1097076-B1 (EP)
Inventor: GRONSKOV LEIF
IPC: B61K9/12
Filed: 1999-07-12
Granted: 2004-10-06
Abstract: Method and apparatus for the detection of defective track wheels on rail vehicles such as carriages and/or locomotives, whereby an electromagnetic beam such as a laser beam (9) is directed towards the wheel (5) in a direction substantially at right-angles to the plane of the wheel while the carriage and/or the locomotive is running. A series of signals are recorded corresponding to electromagnetic beams reflected from the wheel (5) substantially at right-angles to the plane of the wheel, and a measurement is carried out of the Doppler frequency change between the transmitted beam (9) and the reflected beam. On the basis hereof, a signal processing is effected for the determination of the vibration pattern of the relevant wheel, and a determination of the condition of the relevant wheel is carried out on the basis of the vibration pattern.
Patent EP-1098919-B1 (EP)
Inventor: EICHENAUER HERBERT
IPC: C08F279/04
Filed: 1999-07-05
Granted: 2004-02-18
Abstract: L'invention concerne des matières moulables thermodurcissables de type ABS contenant des composants polymère greffé à très haute efficacité, obtenus par polymérisation en émulsion à l'aide de systèmes initiateurs particuliers et dans le respect de conditions réactionnelles particulières.
Patent EP-1091763-B1 (EP)
Inventor: BERGTER WOLFGANG
IPC: A61K51/10
Filed: 1999-06-29
Granted: 2003-09-17
Abstract: The invention relates to a pharmaceutical preparation comprising a radioimmunological conjugate (RIK) for in-vivo elimination of virus-replicating cells in HIV-1, HIV-2, HIV-3, HTLV-1, HTLV-2, HBV, HCV, HDV, CMV, EBV, HHV8 infections and in other chronic virus infections. The radioimmunological conjugate is characterized in that it contains, as immunologically effective constituents; d) a monoclonal antibody or the antigen-binding fragment thereof against a viral or virus-induced antigen expressed on the plasma membrane of virus-infected cells, or; e) a receptor molecule or the fragment thereof with an affinity to an epitope of the viral structural proteins expressed on the plasma membrane of infected cells; or f) a fragment of the cellular receptor molecule, said fragment being modified by mutagenesis, with an affinity to an epitope of the viral structural proteins expressed on the plasma membrane of infected cells. Said conjugate is also characterized in that it contains d) an alpha emitter or a beta emitter as a radioactive constituent. The inventive pharmaceutical preparation also optionally comprises a pharmaceutical carrier and/or adjuvant.
Patent EP-1131571-B1 (EP)
Inventor: EHMANN BRUNO
IPC: F16G13/16
Filed: 1999-10-30
Granted: 2003-02-12
Abstract: The invention relates to a chain link (1) for energy transmission chains, comprising two parallel side links (2, 3) and two cross-members (4, 5) which join the side links. At least one of the cross-members on its inside has a groove (17) running in the width direction of the chain link and presenting a toothing (19). Between the cross-members separating links (6, 7) are arranged which are substantially parallel to the side links (2, 3) and each have at least one tooth (16) designed to engage the toothing (19) of the groove. Each separating link can be displaced between a meshing position in which its tooth (16) engages the toothing in the groove and a release position in which its tooth does not engage said toothing.
Patent EP-1258355-B1 (EP)
Inventor: SAKAMOTO YOSHIAKI
IPC: G11B5/127
Filed: 1999-12-10
Granted: 2006-05-24
Abstract: A printer having a head body (3) for feeding ink from an ink feed part (50) into a plurality of pressure chambers through an ink feed passage and pressurizing each pressure chamber to thereby discharge the ink in the pressure chamber through a nozzle, wherein the head body (3) is formed on the substrate and the substrate is locally removed from the head body (3), whereby the substrate is formed with an ink common passage for communicatingly connecting the ink feed passage and an ink feed port (51) in the ink feed part (50), while the head body (3) and the ink feed part (50) are joined by a joint (8) in the form of a projection left on the substrate, whereby the ink jet head is improved in the degree of integration, reduced in size and increased in rigidity.
Patent EP-1135515-B1 (EP)
Inventor: BROUGH DOUGLAS E
IPC: A61K48/00
Filed: 1999-12-03
Granted: 2006-05-17
Abstract: Provided are methods of modulating the persistence of the expression in a cell of a transgene, such as a transgene in a non-Herpes vector or in at least E4DELTA adenoviral vector, and related systems. One method comprises contacting the cell with a non-Herpes vector comprising and expressing a gene encoding HSV ICP0, whereupon expression of HSV ICP0 the persistence of expression of the transgene is modulated. Further provided is a system for modulating the persistence of expression of a transgene, which system comprises a non-Herpes vector comprising (i) a gene encoding HSV ICP0 and (ii) a transgene, wherein the HSV ICP0 modulates the persistence of expression of the transgene and either the non-Herpes vector comprises the transgene or the system further comprises a vector, in which case the vector comprises the transgene. Another method comprises contacting the cell with an at least E4DELTA adenoviral vector comprising (i) a transgene and (ii) a gene encoding a trans-acting factor, wherein the trans-acting factor modulates the persistence of expression of the transgene and the gene encoding the trans-acting factor is not from the E4 region of an adenovirus. Yet another method comprises contacting a cell simultaneously or sequentially with (i) an at least E4DELTA adenoviral vector comprising a transgene and (ii) a viral vector comprising a gene encoding a trans-acting factor, which is not from the E4 region of an adenovirus and which modulates the persistence of expression of the transgene. Also provided is a system for modulating the persistence of expression of a transgene in an at least E4DELTA adenoviral vector, which system comprises (i) an at least E4DELTA adenoviral vector comprising a transgene and (ii) a gene encoding a trans-acting factor, wherein the gene encoding the trans-acting factor is not from the E4 region of an adenovirus, the trans-acting factor modulates the persistence of expression of the transgene, and either the at least E4DELTA adenoviral vector comprises the gene encoding the trans-acting factor or the system comprises a viral vector, in which case the viral vector comprises the gene encoding the trans-acting factor.
Patent EP-1117399-B1 (EP)
Inventor: HAAPALINNA ANTTI
IPC: A61K31/416
Filed: 1999-09-27
Granted: 2005-02-09
Abstract: The present invention relates to a method for obtaining analgesia by administering 3-(1H-imidazol-4-ylmethyl)-indan-5-ol, its enetiomer or pharmaceutically acceptable ester or salt thereof to a mammal intraspinally, 3-(1H-imidazol-4-ylmethyl)-indan-5-ol, its enantiomer or a pharmaceutically acceptable ester or salt thereof can be administered intraspinally to a mammal obtaining analgesia without side-effects, such as sedation. The present invention also relates to a method for using the drug as an adjunct to anaesthesia by administering it intraspinally.
Patent EP-1044142-B1 (EP)
Inventor: ALBERS MARTIN
IPC: B65D47/20
Filed: 1999-09-16
Granted: 2002-08-28
Abstract: A self-closing valve assembly for installation in a dispensing opening of a container, a seal cap or the like, includes a first closure element having a domed wall portion of resilient material incorporating a passage-opening, said wall portion being resiliently deformable from a closed position into an open position under the influence of a first differential pressure force resulting from pressures acting on its opposite surfaces, and a second closure element having a domed wall portion for sealing the passage-opening when the first closure element is in its closed position. In order to balance the pressure prvailing in a container provided with the valve assembly when a pressure-increasing squeezing force is no longer exerted on the container, the second closure element is adapted to be brought out of its sealing relationship with the passage-opening in the first closure element under the influence of a second differential pressure force resulting from pressures acting on its opposite surfaces, said second differential pressure force being directed oppositely to said first differential pressure force.
Patent IT-1264398-B1 (IT)
Title: Collegamento di almeno due parti di lamiera di una sicurezza di  corrente in un apparecchio di riscaldamento a gas
Inventor: HENSEL MARION
IPC: F23M9/00
Filed: 1993-05-10
Granted: 1996-09-23
Abstract: Collegamento di almeno due parti di lamiera di una sicurezza di corrente (1) in un apparecchio di riscaldamento a gas. Per evitare, specialmente in una sicurezza di corrente, una perdita di materiale e per migliorare il posizionamento di disposizione delle parti di lamiera, la stabilità e la tenuta ermetica verso i gas, si prevede che le due parti di lamiera (20, 21) sono munite, come di per sé noto, di deformazioni che sono eseguite quali improntature (23) imbutite comuni, laddove la parte (24) sporgente convessa è munita di una ribassatura (25) disposta sul suo lato frontale, sostanzialmente centricamente.(Figura 1).
Patent IT-1312114-B1 (IT)
Title: Catalytic composition useful in aromatization of aliphatic hydrocarbons comprises gallium, at least one lanthanide and a zeolite from MFI and/or MEL families
Inventor: AMARILLI STEFANO
IPC: C07C/
Filed: 1999-06-24
Granted: 2002-04-04
Abstract: Catalytic composition comprises gallium (I), at least one element selected from lanthanides (II) and a zeolite (III) belonging to the MFI and/or MEL families. The crystal lattice of the zeolite is made up of silicon oxide and at least one metal oxide selected from aluminum oxide, boron oxide or gallium oxide. Independent claims are included for the following: (A) preparing the catalytic composition by: (i) treating (III) with (I) or (II), treating the obtained product with the (II) or (I), and drying and calcining; or (ii) treating the zeolite with a mixture of (I) and (II), and drying and calcining; (B) preparing aromatic hydrocarbon compounds by contacting at least one 3-6C aliphatic hydrocarbon with a catalytic composition.
Patent IT-1290603-B1 (IT)
Inventor: HOHENBICHLER GERALD
IPC: B22D11/06
Filed: 1997-05-02
Granted: 1998-12-10
Abstract: A casting wheel for the continuous casting of strips of metal has a core and sleeve of heat-conductive material which is shrunk on the core, and circumferential cooling ducts arranged between the core and the sleeve, which are connected with coolant supply line and coolant discharge line. The coolant is guided from the radially extending supply line into cooling ducts and from cooling ducts into the radially extending discharge line by means of a guiding element that can be inserted in cooling ducts.
Patent IT-1267405-B1 (IT)
Title: Espresso coffee machine
Inventor: CORTESE VIRGINIO
IPC: A47J/
Filed: 1994-03-11
Granted: 1997-02-05
Abstract: An espresso coffee machine 1, in which a coffee holding cup 48 is connected in removable fashion to a fixed tubular support 18 and underneath a pressurised hot water supply spout 44, and it has an annular edge coupled in fluid-tight manner to a seal 37 surrounding the supply spout 44; the fixed tubular support 18 accommodates a hydraulic cylinder 21 operated by the pressurised hot water and having a piston 31 which can move toward the cup 48 and supporting the seal 37. <IMAGE>
Patent JP-2993496-B1 (JP)
Title: リミッタ回路付きミキサ
IPC: H04B1/16
Filed: 1998-07-31
Granted: 1999-12-20
Abstract: 【要約】
【目的】  受信回路のミキサ回路において、ＲＦ信号が 強いときに生じるミキサ回路の出力電力低下を防止す る。
【構成】  入力信号が強いときにインピーダンスが低く なるように構成されたリミッタ回路２０を、ミキサ回路 １０の信号入力端子に付加することによって、入力信号 が強いときにミキサ回路に大振幅の信号が入らないよう にし、その結果、ミキサの入力トランジスタＱ３の飽和 を避けられるため、ミキサ回路の出力電力低下を防い だ。
Patent JP-2962359-B1 (JP)
Title: 半導体集積回路
IPC: G05F1/565
Filed: 1998-08-18
Granted: 1999-10-12
Abstract: 【要約】
【課題】  温度等の動作環境の変化に追従して最適な電 圧を内部回路に供給することができる半導体集積回路を 提供する。
【解決手段】  最小動作電圧検出回路１１ａ内には、電 源端子２に接続されたキャパシタを備えた充放電回路２ １ａが設けられている。また、充放電回路２１ａの制御 を行う充放電制御回路２１ｂが設けられている。基準回 路１１ｂ内には、電源端子２から供給される電圧により 駆動される第１サンプル論理回路２２ａ及び充放電回路 ２１ａによって降圧された電圧により駆動される第２サ ンプル論理回路２２ｂが設けられている。更に、最小動 作電圧検出回路１１ａ内には、第１サンプル論理回路２ ２ａ及び第２サンプル論理回路２２ｂに接続された出力 比較回路２１ｃが設けられている。出力比較回路２１ｃ は第１サンプル論理回路２２ａ及び第２サンプル論理回 路２２ｂの出力信号を比較しその比較結果を充放電制御 回路２１ｂに出力する。