baber/WOPTO huggingface dataset:
Patent MX-2021005847-A (MX)
Title: Suicide gene.
Inventor: REZVANI KATY
IPC: A61K38/19
Filed: 2019-11-18
Abstract: Embodiments of the disclosure encompass particular TNF-alpha mutants that are nonsecretable and membrane bound, thereby providing a target for inhibition in cells that express the mutants. In specific embodiments, the TNF-alpha mutants are utilized as a suicide gene in cells employed for adoptive cell therapy for an individual, wherein at a desired time the individual is provided one or more anti-TNF-alpha antibodies that bind the membrane bound TNF-alpha and elicit complement-dependent cytotoxicity for the cells. The TNF-alpha mutant can also be used as a way of tracking the transduced cells in vivo.
Patent MX-2021006807-A (MX)
Title: Irrigation control system that detects cloud cover from an array of photovoltaic cells and methods for same.
Inventor: KERT KAIDO
IPC: G05D7/00
Filed: 2019-12-11
Abstract: A method for operating an irrigation control system is provided and includes receiving environmental data by the irrigation control system and receiving operational data from an array of photovoltaic cells. The method further includes determining an amount of cloud cover in the sky from the array of photovoltaic cells and calculating an evapotranspiration value for an irrigation zone associated with the irrigation control system based at least in part upon the environmental data and the operational data. The method still further includes determining an irrigation schedule for the irrigation zone based at least in part upon the evapotranspiration value and executing the irrigation schedule to irrigate the irrigation zone. An irrigation control system is also provided.
Patent MX-2021009989-A (MX)
Title: Chain slack detection system.
Inventor: OKROY MARTIN
IPC: B66F9/08
Filed: 2019-10-10
Abstract: A materials handling vehicle includes a mast, a load handling structure supported on the mast, one or more operator controls, and a lifting structure having a chain structure for performing a lifting and lowering of the load handling structure. The materials handling vehicle further includes a height sensor for generating a height signal corresponding to vertical movement of the load handling structure relative to the mast, and a vehicle control module for processing the height signal received from the height sensor and an operator control signal received from the one or more operator controls. The vehicle control module evaluates the height signal and the operator control signal and disables one or more vehicle functions if the height signal does not correspond to the operator control signal.
Patent MX-2021014700-A (MX)
Title: Adeno-associated virus vector variants for high efficiency genome editing and methods thereof.
Inventor: CHATTERJEE SASWATI
IPC: A61K48/00
Filed: 2017-03-23
Abstract: Adeno-associated virus (AAV) Clade F vectors or AAV vector variants (relative to AAV9) for precise editing of the genome of a cell and methods and kits thereof are provided. Targeted genome editing using the AAV Clade F vectors or AAV vector variants provided herein occurred at frequencies that were shown to be 1,000 to 100,000 fold more efficient than has previously been reported. Also provided are methods of treating a disease or disorder in a subject by editing the genome of a cell of the subject via transducing the cell with an AAV Clade F vector or AAV vector variant as described herein and further transplanting the transduced cell into the subject to treat the disease or disorder of the subject. Also provided herein are methods of treating a disease or disorder in a subject by in vivo genome editing by directly administering the AAV Clade F vector or AAV vector variant as described herein to the subject.
Patent MX-2021015592-A (MX)
Title: Combination therapy methods, compositions and kits.
Inventor: VILLOSLADA DIAZ PABLO
IPC: A61K31/225
Filed: 2020-07-02
Abstract: Invention relates to combinations comprising: a) a compound of formula (I) or a pharmaceutically or veterinary acceptable salt thereof, wherein: R1 R2 and R3 have particular meaning; and (b) one or more drugs selected from the group consisting of i) a compound of formula (IV), or a pharmaceutically or veterinary acceptable salt thereof, wherein R5 and R6 have particular meaning, ii) a sphingosine-1-phosphate receptor inhibitor (S1PR modulator), and iii) a Signal transducer and activator of transcription 3 (STAT3) inhibitor. Particular combinations and single pharmaceutical compositions and kits of parts are disclosed. These combinations, single pharmaceutical compositions and kits of parts are for use in the treatment and/or prevention of an inflammatory neurological disease or condition which can result in the destruction or degeneration of axons or myelin in a subject in need thereof.
Patent MX-2022000791-A (MX)
Title: Method and apparatus for pdcch monitoring adaptation.
Inventor: WEI CHIAHUNG
IPC: H04L5/02
Filed: 2020-08-11
Abstract: A method includes receiving, through RRC signaling from a base station, indicating a dormancy cell group having at least a first serving cell and a second serving cell, receiving a first indicator indicating a dormant behavior to the first serving cell is to be activated when the first serving cell is activated, receiving a second indicator indicating a dormant behavior to the second serving cell is to be deactivated when the second serving cell is activated. The method also includes receiving a cell activation indication to activate the first serving cell and the second serving cell, activating the first serving cell and the second serving cell, applying the dormant behavior to the first serving cell based on the first indicator when the first serving cell is activated, and not applying the dormant behavior to the second serving cell based on the second indicator when the second serving cell is activated.
Patent MX-2022001340-A (MX)
Title: Immersion device for temperature measurement and method for position detection.
Inventor: NEYENS GUIDO
IPC: B22D2/00
Filed: 2022-01-31
Abstract: Immersion Device for Temperature Measurement and Method for Position Detection Abstract The invention relates to an immersion device and a method for detecting a position of an optical cored wire using an immersion device. An immersion device (10) for measuring a temperature of a metal melt (64) inside an electric arc furnace (60) vessel (62) with an optical cored wire (50) comprises a blowing lance (28) for blowing purge gas into an entry point to the vessel (62) and a detecting means for detecting a position of the optical cored wire (50). The optical cored wire (50) can be moved in a feeding channel (20) and/or in the blowing lance (28) relative to the entry point. The detecting means is configured to detect the presence of the optical cored wire (50) in or close to the blowing lance (28). This enables short distances between the leading end of the fiber and the melt and, thus, short time intervals between temperature measurement sequences.
Patent MX-2022001614-A (MX)
Title: Increased emission collection efficiency in integrated optical devices.
Inventor: KABIRI ALI
IPC: G01N21/64
Filed: 2020-08-06
Abstract: Apparatus and methods for improving optical signal collection in an integrated device are described. A microdisk (1-605) can be formed in an integrated device and increase collection and/or concentration of radiation incident on the microdisk (1-605) and re-radiated by the microdisk (1-605). An example integrated device that can include a microdisk (1-605) may be used for analyte detection and/or analysis. Such an integrated device may include a plurality of pixels, each having a reaction chamber (1-130) for receiving a sample to be analyzed, an optical microdisk (1-605), and an optical sensor (1-122) configured to detect optical emission from the reaction chamber (1-130). The microdisk (1-605) can comprise a dielectric material having a first index of refraction that is embedded in one or more surrounding materials (1-610) having one or more different refractive index values.
Patent MX-2022002466-A (MX)
Title: B-cell maturation complex car t construct and primers.
Inventor: GEORGE REBECCA
IPC: C12Q1/6886
Filed: 2020-08-28
Abstract: The present invention provides probe and primer sets, and related methods and kits, for generating B-cell maturation antigen chimeric antigen receptor (CAR) T cells. The invention also provides probe and primer sets, and related methods and kits, for performing quantitative polymerase chain reactions to quantitate B-cell maturation antigen CAR transgene integration into a CAR T drug product.
Patent MX-2022004343-A (MX)
Title: Engineered antibodies as molecular degraders through cellular receptors.
Inventor: SPIEGEL DAVID
IPC: A61K47/68
Filed: 2020-10-09
Abstract: The present disclosure provides, in one aspect, bifunctional compounds that can be used to promote or enhance degradation of certain circulating proteins. In certain embodiments, the circulating protein mediates a disease and/or disorder in a subject, and treatment or management of the disease and/or disorder requires degradation, removal, or reduction in concentration of the circulating protein in the subject. Thus, in certain embodiments, administration of a compound of the disclosure to the subject removes or reduces the circulation concentration of the circulating protein, thus treating, ameliorating, or preventing the disease and/or disorder.
Patent MX-2022006213-A (MX)
Title: Substituted 1,5-naphthyridines or quinolines as alk5 inhibitors.
Inventor: FENSTER ERIK
IPC: A61P11/00
Filed: 2020-11-20
Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.
Patent MX-2022008314-A (MX)
Title: Connectors for hardline coaxial cable.
Inventor: MONTENA NOAH P
IPC: H01R9/05
Filed: 2021-01-07
Abstract: A coaxial cable connector includes a nut housing having a rearward cable receiving end and a forward end opposite said rearward end, a front nut assembly coupled to the forward end of the nut housing, and a conductive metal tubular insert shaft supported within the nut housing or the front nut assembly. The front nut assembly includes an entry body housing and a conducti ve terminal pin extending from a forward end of the front nut assembly, and the conductive metal tubular insert shaft has a rearward end portion. A nonconductive plastic tubular support sleeve has a forward end portion coupled with the rearw ard end portion of the conductive metal tubular insert shaft, a tubular gripping ferrule radially surrounds the metal insert shaft and the plastic support sleeve, and a tubular outer sleeve radially surrounds at least a portion of said gripping ferrule. The gripping ferrule and the tubular outer sleeve are configured to be moved relative to one another in an axial direction such that the gripping ferrule and the tubular outer sleeve are configured to engage one another, thereby causing the gripping ferrule to radially compress around the conductive metal tubular insert shaft and the nonconductive plastic tubular support sleeve.
Patent MX-2022009675-A (MX)
Title: Uplink information based on wake-up signal.
Inventor: WU CHUNLI
IPC: H04W52/02
Filed: 2020-02-06
Abstract: Embodiments of the present disclosure relate to uplink control information for uplink information based on wake-up signals. According to embodiments of the present disclosure, the terminal device determines based on transmission information at a first time point whether a predetermined number of the one or more occasions overlaps with active time of the terminal device. The terminal device determines the configuration for transmitting the uplink information based on the determination. In this way, ambiguity has been reduced and the flexibility of the network is improved.
Patent MX-2022009993-A (MX)
Title: System, method, and apparatus for monitoring, regulating, or controlling fluid flow.
Inventor: KAMEN DEAN
IPC: A61M5/168
Filed: 2015-09-15
Abstract: An apparatus, system and method for regulating fluid flow are disclosed. The apparatus includes a flow rate sensor and a valve. The flow rate sensor uses images to estimate flow through a drip chamber and then controls the valve based on the estimated flow rate. The valve comprises a rigid housing disposed around the tube in which fluid flow is being controlled. Increasing the pressure in the housing controls the size of the lumen within the tube by deforming the tube, therefore controlling flow through the tube.
Patent MX-2022010111-A (MX)
Title: Electronic rupture disc with atmospheric chamber.
Inventor: DUFOUR YANN
IPC: E21B34/06
Filed: 2021-02-18
Abstract: An electronic trigger system includes a longitudinal housing including detection, electronics, and actuation sections disposed therein. The detection section includes a pressure sensor for receiving a predetermined pressure signal, and an electronic control board including at least one battery is disposed in the electronics section. The actuation section includes a prefill chamber, a setting piston disposed in the prefill chamber, an actuation device, an atmospheric chamber, and a pressure port. A predetermined amount of prefilled fluid at hydrostatic pressure is trapped between the setting piston and the actuation device in the prefill chamber. The actuation device isolates the prefilled fluid at hydrostatic pressure in the prefill chamber from the atmospheric chamber. Actuation occurs when, upon receipt of the predetermined pressure signal by the pressure sensor, the electronic control board transmits power to the actuation device, causing the prefilled fluid to flow through the actuation device and into the atmospheric chamber.
Patent MX-2022012004-A (MX)
Title: Construction method and application of antigen-specific binding polypeptide gene display vector.
Inventor: ZHOU CHEN
IPC: C12N15/10
Filed: 2021-03-26
Abstract: Disclosed in the present application is a method for constructing an antigen-specific binding polypeptide gene display vector. The method comprises processing by using a restriction endonuclease that specifically recognizes a restriction site to obtain four nucleic acid fragments having specific sticky ends, and then enabling the nucleic acid fragments to directionally ligate. Further disclosed in the present application are an antigen-specific binding polypeptide gene display vector produced according to the method and a bacterial library. The method described in the present application can be used to effectively screen antigen-specific antigen-binding polypeptides or fragments thereof.
Patent MX-2022012569-A (MX)
Title: Mint flavor compositions.
Inventor: HOKE II STEVEN HAMILTON
IPC: A61Q11/00
Filed: 2021-04-29
Abstract: Mint flavor compositions comprising certain mint flavor components provide a more cost-effective alternative to naturally derived mint oils.
Patent MX-2022013791-A (MX)
Title: Novel extended release composition of tofacitinib, its derivatives and salts.
Inventor: DAUD ANWAR
IPC: A61K9/00
Filed: 2021-05-17
Abstract: The present invention relates to solid composition of Tofacitinib and salt thereof, and process of manufacture thereof. The present invention relates to non-osmotic an extended release composition comprising Tofacitinib or salt thereof, mixture of polyethylene oxides along with one or more pharmaceutically acceptable excipient. The non-osmotic an extended release composition of Tofacitinib or salt thereof is used in the treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ulcerative Colitis.
Patent MX-2022013802-A (MX)
Title: Ethylene interpolymer products having unique melt flow-intrinsic viscosity (mfivi) and high unsaturation.
Inventor: SIBTAIN FAZLE
IPC: C08F210/16
Filed: 2021-05-06
Abstract: This disclosure relates to ethylene interpolymer products comprising a Melt Flow-Intrinsic Viscosity Index value, <i>MFIVI</i>, of from â¥ 0.05 to â¤ 0.80; a first derivative of a melt flow distribution function, formula (I) at a loading of 4000 g, of from â¥ -1.85 to â¤ -1.51; a sum of unsaturation, <i>SUM</i> <sup> <i>U</i> </sup>, from â¥ 0.047 to â¤ 0.100 unsaturations per 100 carbon atoms; and a residual catalytic metal of from â¥ 0.03 to â¤ 5 ppm of hafnium. Ethylene interpolymer products comprise at least two ethylene interpolymers. Ethylene interpolymer products are characterized by a melt index (I<sub>2</sub>) from 0.3 to 500 dg/minute, a density from 0.855 to 0.975 g/cc and from 0 to 25 mole percent of one or more a-olefins. Ethylene interpolymer products have polydispersity, M<sub>w</sub>/M<sub>n</sub>, from 1.7 to 25; and CDBI<sub>50</sub> values from 1% to 98%. These ethylene interpolymer products have utility in flexible as well as rigid applications.
Patent MX-2022014196-A (MX)
Title: Branched products.
Inventor: KILLEBREW KYLE
IPC: C12M1/00
Filed: 2021-06-03
Abstract: A process for producing isomerized olefins, branched aldehydes, branched alcohols, branched surfactants and other branched derivatives through isomerization, hydroformylation, hydrogenation, surfactant forming reactions and other derivative forming reactions.
Patent MX-PA01002304-A (MX)
Title: Process and apparatus for upgrading hydrocarbon feeds containing sulfur, metals, and asphaltenes.
Inventor: RETTGER PHILIP B
IPC: C10G67/04
Filed: 1999-08-31
Abstract: Upgrading of a hydrocarbon feed (11) containing sulfur, metals, and asphaltenes involves applying the feed (11) to a distillation column (14) for producing a substantially asphaltene-free, and metal-free distillate fraction and a non-distilled fraction (18) containing sulfur, asphaltenes, and metals. At least some of the substantially asphaltene-free, and metal-free distillate fraction is converted to a hydrogen donor diluent. The non-distilled fraction (18) is processed in a solvent deasphalting unit (19) for producing a deasphalted oil stream (20) and an asphaltene stream (21). After a combined stream (23)is formed from the hydrogen donor diluent and the deasphalted oil stream, the combined stream (23) is thermally cracked forming a thermally cracked stream (25) that is applied to the distillation columnn (14).
Patent MX-PA01008753-A (MX)
Title: Conductive or static dissipative coating.
Inventor: PROPST CHARLES W JR
IPC: D21H19/58
Filed: 2000-03-02
Abstract: Electrically conductive or static dissipative coating, films, or laminae in a laminate construction suitable for packaging of sensitive electronic components. The electrical conductive or static dissipative properties are achieved by including an effective amount of a quaternary ammonium compound into a base resin.
Patent MX-PA01009417-A (MX)
Title: A method and machine for manufacturing molded structures using zoned pressure molding.
Inventor: DAVID H STEWART
IPC: B29C70/54
Filed: 2000-03-17
Abstract: A method for manufacturing a molded structure in a press that includes the steps of positioning a preform (24) having a thickness in the lower mold (20), placing a quantity of resin adjacent the preform (24) so as to create a resin reservoir, and then selectively actuating one or more of the pressure actuators (28) to apply pressure to the resin reservoir to force at least a portion of the resin reservoir to infuse through the thickness of the preform (24). After the step of positioning, a top cover (32) may be placed upon the preform (24). The step of selectively actuating one or more of the pressure actuators (28) attached to an upper platen (60), may include a computer for controlling the pressure actuators (28).
Patent MX-PA01009785-A (MX)
Title: Sieve bed for a sifting machine.
Inventor: SAWALL KIRK
IPC: B07B1/46
Filed: 2000-04-26
Abstract: The invention pertains to a sieve bed for a sifting machine, consisting of rectangular sieve elements (10), which are attached to a support frame (1) with their edges abutting each other, the support frame being provided with mushroom-shaped mounting pins (3), each of which is provided with a head which engages in an interlocking manner in corresponding recesses (11a and 11b) of the sieve elements (10). To facilitate the assembly and disassembly of the sieve elements in a sieve bed of this type and to protect the connection from premature wear the invention proposes that the receptacle (11) for the head (4) of the mounting pin (3) be closed off at the top; that the receptacle (11) for the head (4) of the mounting pin (3) be provided at the bottom with an entrance opening for the head (4) of the mounting pin (3); and that the wall of the receptacle (11) be provided with an inward-projecting bed (12), which can be snapped under the head (4) of the mounting pin (3).
Patent MX-PA01010483-A (MX)
Title: Nucleic acids coding for novel truncated cart proteins, corresponding truncated cart polypeptides and their use for therapeutic and diagnostic purposes.
Inventor: DIXON ALISTAIR
IPC: C07K14/475
Filed: 2000-04-14
Abstract: The present invention is directed to nucleic acids encoding novel truncated CART polypeptides, particularly CART proteins having 88 amino acids in length, as well as nucleic acid fragments thereof. The invention also pertains to a family of recombinant vectors containing a nucleic acid encoding such truncated CART polypeptide and to recombinant host cells containing such recombinant vectors. The invention also deals with a truncated CART protein particularly a truncated CART protein having 88 amino acids in length as well as antibodies specifically directed against this protein, these antibodies being useful as diagnostic reagents. The invention also relates to the use of CART protein particularly a truncated CART protein having 88 amino acids in length or fragments for the identification and characterisation of ligands which bind to CART protein or its receptor(s). The invention also relates to the use of the nucleic acids encoding the truncated CART proteins of the invention or the truncated CART proteins themselves for therapeutic purposes and particularly to decrease or prevent neuronal degeneration and to promote neuronal regeneration and restoration of function, to treat addiction by aiding clearance of the polypeptide or its truncated forms in vitro and in vivo and also in order to regulate food intake.
Patent MX-PA01012506-A (MX)
Title: Interactive demand management.
Inventor: DALE CONTRATTO
IPC: G06Q10/00
Filed: 2001-04-05
Abstract: A system and method is disclosed which allows the aggregation of the demands of various buyers, providing an incentive for suppliers to bid to supply those demands in an auction. The system and method operates by scanning a database which contains a listing of goods or services sought by various people or entities. Thereafter, similar goods or services are grouped together and presented to various vendors. The vendors are given the opportunity to bid on the group of similar goods or services. Such a bid may vary from the originally purchased goods or services as long as the bid is within a predetermined range. The vendor which presents the optimum bid within a predetermined period of time is selected as the provider of the goods or services and proceeds to supply the goods or services at the bid upon amount.
Patent MX-PA02000190-A (MX)
Title: Preparation of a therapeutic composition.
Inventor: FRIEDLAND BERNARD
IPC: A61K38/01
Filed: 2000-06-23
Abstract: Product R, a novel therapeutic composition for treating viral infections and stimulating the immune system, comprises nucleotides and peptides that have molecular weights not more than 14 KDa and substantially not more than 8 KDa. The composition has a light absorption spectrum with typical absorption ratios of 1.998 at 260nm/280nm and 1.359 at 260nm/230nm.