baber/WOPTO huggingface dataset:
Patent NZ-608461-A (NZ)
Title: Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
Inventor: HASSANEIN WALEED
IPC: A01N1/02
Filed: 2008-04-24
Abstract: Discloses an organ care system comprising: a chassis, an organ chamber, wherein the organ chamber comprises a fluid conduit with a first interface configured to connect to an aorta of the heart and a second interface configured to connect to a pulmonary vein of the heart; a lactate A sensor configured to measure lactate in the first interface; a lactate V sensor configured to measure lactate in the second interface; and a processor configured to calculate a Lactate V-A differential using lactate values measured by the Lactate A sensor and the Lactate V sensor, wherein the Lactate V-A differential is calculated at two different times to correlate a change between the V-A lactate differentials over time with suitability of the heart for transplantation.
Patent NZ-613948-A (NZ)
Title: Humanized m-csf mice
Inventor: MURPHY ANDREW J
IPC: A01K67/027
Filed: 2012-02-14
Abstract: Disclosed is a humanised M-CSF mouse, comprising: a nucleic acid sequence, which sequence encodes a human M-CSF protein and is operably linked to the promoter of the mouse M-CSF gene at the mouse M-CSF locus.
Patent NZ-615721-A (NZ)
Title: Immunogenic compositions in particulate form and methods for producing the same
Inventor: LEENHOUTS CORNELIS JOHANNES
IPC: C12N15/62
Filed: 2012-03-22
Abstract: Disclosed is an immunogenic composition in particulate form, comprising: i. a non-viable bacterium-like particle (BLP) obtained from a Gram-positive bacterium as particulate carrier; ii. oligomers of a recombinantly produced polypeptide attached non-covalently to said BLP, wherein the recombinant polypeptide comprises (a) an N- or C-terminal antigenic domain, comprising at least one surface exposed polypeptide of pathogenic or tumour origin, or antigenic part thereof, the antigenic domain being fused to (b) an oligomerization domain, said oligomerization domain being fused via (c) a linker domain to (d) a peptidoglycan binding domain consisting of a single copy of a LysM domain mediating the non-covalent attachment of the polypeptide to the BLP, and wherein the polypeptide as a whole contains only a single copy of a LysM domain; and iii. a pharmaceutical acceptable diluent or excipient.
Patent NZ-616183-A (NZ)
Title: Method for egfr directed combination treatment of cancer
Inventor: DENIS LOUIS
IPC: A61K45/00
Filed: 2012-05-16
Abstract: Discloses use of an irreversible tyrosine kinase inhibitor (TKI) selected from the group consisting of EKB-569 (pelitinib), HKI-272 (neratinib), HKI-357, CI-1033, BIBW 2992, PF-00299804 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)prop-2-en-1-one, WZ 3146, WZ 4002, and WZ 8040, or a pharmaceutically acceptable salt thereof, for preparation of a medicament for treating of a human patient suffering from a cancer driven by deregulated Human Epidermal Growth Factor Receptor (HER/Human EGFR) selected from the group consisting of non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), malignant glioma, breast cancer, esophageal cancer, gastric cancer, renal cancer, cervical cancer, prostate cancer, ovarian cancer, pancreatic cancer, hepatocellular cancer, and colorectal cancer (CRC), including metastatic forms thereof, wherein the medicament is for use in combination with a Human EGFR targeted monoclonal antibody (mAB) selected from the group consisting of cetuximab, panitumumab, zalutumumab, nimotuzumab, matuzumab and necitumumab, wherein the treating comprises administering the TKI according to a continuous regimen based on an average daily dose in the range of 10 to 50 mg and co-administering the mAB according to a dosing regimen ranging from an average weekly iv dose of 50 to 500 mg/m2 repeated thrice, twice or once a week, once in two weeks, once in three weeks or at least once monthly.
Patent NZ-623554-A (NZ)
Title: Therapeutic compositions for the treatment and prevention of gastrointestinal cancer
Inventor: KERRY PAUL
IPC: A61P35/00
Filed: 2013-04-05
Abstract: The disclosure relates to use of a compound of formula (IA) or (II) and optionally with at least one additional therapeutic agent, in the manufacture of a composition for treating or preventing gastric cancer or throat cancer in a subject, wherein the variables are as defined in the specification. Also described are pharmaceutical compositions comprising compounds including 5-phenylpenta-2,4-dienoic acid, 3-methyl-3-butenyl caffeic acid, 1,1-dimethylallyl caffeic acid, pinobanksin-3-acetate, tectochrysin, pinostrobin chalcone, benzyl ferulate and benzyl isoferulate. The composition may include as additional therapeutic agent selected from an anti-tumour agent, preferably the anti-tumour agent is selected from an anti-tumour food factor, a chemotherapeutic agent, or an immunotherapeutic agent. These pharmaceutical compositions are useful in the treatment or prevention of gastrointestinal cancers, and the resensitisation of gastrointestinal cancers.
Patent NZ-623658-A (NZ)
Title: Method, in particular for generating snow, and device for carrying out the method
Inventor: GREGA SAMUEL
IPC: F25C3/04
Filed: 2012-10-01
Abstract: Disclosed is a snow production device for producing snow from water. The device includes a low-pressure device (2) with a pumping device (2.1) to which a cleaning device (2.2) is connected. A high-pressure device (3) is connected to a snow cannon (3.3), and a distributor device (2.4) whose high-pressure pump separates the low-pressure device (2) from the high-pressure device (3). Pressure excitation blocks (3.5) have at least one pressure excitation device are connected via a pressure line (3.1) to the high-pressure device (3) upstream of the snow cannon (3.3). The low-pressure device (2) has a main excitation device (2.3) which is located downstream of the cleaning device (2.2) and on which an excitation device (2.35) is located. The pressure excitation device (3.5.1) and the excitation device (2.35) have a common chamber (3.42) which has a control electrode located in sheath (3.41) and a polarization electrode located in a sheath. A high-power source introduces an electromagnetic alternating signal into the control electrode when the pressure excitation device (3.51) or the excitation device (2.35) is located in water.
Patent NZ-626419-A (NZ)
Title: Cell-scaffold constructs
Inventor: ILAGAN ROGER
IPC: A61L27/38
Filed: 2009-11-04
Abstract: Disclosed is an implantable construct for replacement of a defective bladder in a subject comprising a) a tubular scaffold having a first open end configured for anastomosis to an opening in the subject’s abdominal wall, a second open end configured to connect to a ureter; and b) an autologous smooth muscle cell (SMC) population that is not derived from the defective bladder, deposited on or in a surface of the tubular scaffold, wherein the cell population is a smooth muscle cell population derived from adipose tissue or peripheral blood, and wherein the implantable construct is adapted for temporary storage and passage of urine.
Patent NZ-703426-A (NZ)
Title: Monitored component connection, wind power system, method for monitoring a component connection for inadvertent loosening of the component connection in the connected state
Inventor: JEPSEN TORSTEN
IPC: G01M5/00
Filed: 2013-04-18
Abstract: The invention relates to a monitored component connection with a first component forming a retaining part, a second component forming a mating part, a connection part that retains the second component on the first component in the connected state, wherein the connection part engages in a connecting recess in said mating part. According to the invention, in order to monitor for inadvertent weakening of the component connection in the connected state, a test pressure can be applied to the connecting recess, and said test pressure can be monitored for a fault deviation that is sufficient for indicating a connection weakening of the component connection in the connected state.
Patent NZ-714554-A (NZ)
Title: Pharmaceutical formulations of a hif hydroxylase inhibitor
Inventor: CONCA DAVID
IPC: A61K47/02
Filed: 2014-06-05
Abstract: The present disclosure relates to pharmaceutical formulations of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid and methods of use thereof in the treatment of e.g. anemia. The formulation comprises a coating comprising titanium dioxide and a dye which stabilises [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid from light-induced degradation.
Patent NZ-720511-A (NZ)
Title: Compounds useful as inhibitors of atr kinase and combination therapies thereof
Inventor: POLLARD JOHN ROBERT
IPC: A61P35/00
Filed: 2013-04-05
Abstract: [0222] The present invention relates to compounds useful as inhibitors of ATR protein kinase and combination therapies thereof. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. [0223] The compounds of this invention have formula I: wherein the variables are as defined herein.
Patent NZ-723535-A (NZ)
Title: Combination therapies with anti-cd38 antibodies
Inventor: DOSHI PARUL
IPC: C07K16/00
Filed: 2015-02-25
Abstract: The present invention relates to combination therapies with anti-CD38 antibodies (Daratumumab) and CHOP (cyclophosphamide, doxorubicin hydrochloride, vincristine sulfate and prednisone). The antibodies have therapeutic applications to haematological malignancies.
Patent NZ-725918-A (NZ)
Title: Carboxamide derivatives
Inventor: AHMED MAHBUB
IPC: C07D413/14
Filed: 2015-05-14
Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Patent NZ-736292-A (NZ)
Title: Package comprising a stack of absorbent tissue paper material and a packaging
Inventor: WALLENIUS HANS
IPC: B65B63/02
Filed: 2015-06-22
Abstract: A package (100) comprising a stack (10) of absorbent tissue paper material and a packaging (20), wherein the absorbent tissue paper material forms panels having a length (L), and a width (W). The panels are piled on top of each other to form a height (H) extending between a first end surface and a second end surface (11, 12) of the stack. The absorbent tissue paper material comprises at least a dry crepe material and the stack, when in said package, has a selected packing density D0 of 0.25 to 0.65 kg/dm3, and exerts a force along the height (H) towards the packaging. The packaging maintains the stack in compressed condition with said selected packing density D0. The invention provides a compressed tissue package that reduces the bulk of the stack for transportation and loading into a dispenser, while maintaining tissue paper quality and reducing the spring back force exerted on the packaging material. This is achieved by temporarily compressing the stack to a height smaller than the final packing height.
Patent NZ-744209-A (NZ)
Title: Broadband satellite communication system using optical feeder links
Inventor: MENDELSOHN AARON
IPC: H04B10/118
Filed: 2016-12-30
Abstract: Broadband satellite communications systems using optical feeder links are disclosed. Various optical modulation schemes are disclosed that can provide improved capacity for fixed spot beam broadband satellite systems.
Patent NZ-744250-A (NZ)
Title: Apparatus for moving ropeway vehicles in a ropeway system
Inventor: MORITZHUBER JOHANNES
IPC: B61B12/02
Filed: 2016-11-17
Abstract: An apparatus for moving ropeway vehicles in a ropeway system, in which the height of the conveying wheel is relative to the ropeway vehicles can be adjusted by a lifting device which allows movement to be stopped without risk of locking or wedging abutting surfaces, so that the lifting device can be easily readjusted. The apparatus includes at least one conveying wheel which can be adjusted in height in relation to the ropeway vehicles, by means of a lifting device, in order to be brought into abutment against said vehicles, as a result of which the latter can be displaced along a track by means of the at least one conveying wheel. An electric lifting device is provided here and is designed with an electric drive motor, with a threaded sleeve (42) or the like, which can be retained in its height position and rotated by said drive motor, and with a lifting spindle (44), which can be adjusted in height by the threaded sleeve (42) and by means of which the at least one conveying wheel can be adjusted in height, wherein the threaded sleeve (42) and the lifting spindle (44) are designed, on the associated upper and lower end surfaces, with stops (49a, 50a, 53a, 54a), which are located at least more or less in planes normal to the direction of rotation of the threaded sleeve (42) or the like and, in the upper and the lower end positions of the lifting spindle (44), end up in abutment against one another, as a result of which any further rotation of the threaded sleeve (42) is prevented.
Patent NZ-756241-A (NZ)
Title: Combination therapies for treatment of bcma-related cancers and autoimmune disorders
Inventor: RIDDELL STANLEY
IPC: A61K31/55
Filed: 2018-02-16
Abstract: The present disclosure relates to methods for using BCMA-specific binding molecules (such as a BCMA-specific chimeric antigen receptor or antibody) in combination with γ-secretase inhibitors, which can be done concurrently or sequentially, to treat or prevent a B-cell related proliferative disease, such as a cancer or autoimmune disease, or the like. A BCMA-specific binding molecule in combination with γ-secretase inhibitor can be used in, for example, adoptive immunotherapy.
Patent NZ-758354-A (NZ)
Title: Anti-ccl17 antibodies
Inventor: WHEELER JOHN
IPC: A61K39/395
Filed: 2014-11-06
Abstract: The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
Patent NZ-771216-A (NZ)
Title: Screed plug, screeding guide and screeding method
Inventor: ROB FORD
IPC: E04F15/12
Filed: 2020-12-17
Abstract: During the laying of concrete, screed, and the like, there is the potential for unwanted material to enter conduits such as drains. In addition, the presence of the conduits in the area in which concrete and screed is being laid may complicate the process of levelling the concrete or screed. A screed plug for placement in an open end of a conduit comprises: a top plate; a second surface; at least one side wall extending between the top plate and the second surface; a recess formed in the top plate; and a handle for manipulating the screed plug. The handle is housed within the recess and is reversibly movable from at least a first position within the recess and a second position projecting from the recess.
Patent NZ-777061-A (NZ)
Title: Chlorine generator system
Inventor: MCCAGUE MICHAEL
IPC: A61H33/00
Filed: 2018-05-29
Abstract: An electrode cartridge comprising: a single piece first electrode including a vertical portion constructed to generate chlorine, the vertical portion forming into a horizontally extending base portion which then forms into an upwardly extending electrical contact arm which is spring biased outwardly away from a side surface of the electrode cartridge and compressible inwardly toward said side surface against the spring bias; and a single piece second electrode including a vertical portion constructed to generate chlorine, the vertical portion forming into a horizontally extending base portion which then forms into an upwardly extending electrical contact arm which is spring biased outwardly away from a side surface of the electrode cartridge and compressible inwardly toward said side surface against the spring bias.
Patent PT-102330-A (PT)
Title: Industrial use of multi enzymatic vegetable extracts consists of application to leather, fish and meat, with high proteolytic activity
Inventor: TEIXEIRA G
IPC: C12N11/18
Filed: 1999-07-07
Abstract: The industrial use of multi-enzymatic vegetable extracts comprises for example, application to leather and foodstuffs. The extracts are obtained from Opuntia cactaceae plant fruits, with acid cysteine proteases derived from Opuntia licus-indica fruit extracts.
Patent RU-94000001-A (RU)
Inventor: LORAN O B
IPC: A61K9/06
Filed: 1994-01-05
Abstract: FIELD: medicine, urology, pharmacy. SUBSTANCE: proposed ointment has active components - nitroglycerol, papaverine hydrochloride, euphylline, dimexide, testosterone propionate and an ointment base - polar fox fat, aqueous lanolin and aromatic addition - citral essential oil. After treatment with proposed ointment the significant improvement of sexual potency is noted in 83% patients. Ointment is effective at different erection disorder types, its shows safety and can be used in medicine. EFFECT: new type of curative effect, high effectiveness.
Patent RU-94003553-A (RU)
Inventor: GOPIENKO V G
IPC: C09C1/64
Filed: 1994-02-03
Abstract: FIELD: production of aluminium paste. SUBSTANCE: proposed paste contains (mass %): aluminium scale 50-85, stearine 1-5, aluminium hydroxide 3-10 and white spirit. EFFECT: improves quality of desired product. 1 tbl
Patent RU-94009030-A (RU)
Inventor: TARASENKO V V
IPC: A01D46/00
Filed: 1994-03-15
Abstract: FIELD: agricultural engineering; tomato, root and tuber harvesters. SUBSTANCE: harvester has frame, cutting device, elevator, mechanism for separating juicy fruits vegetables or roots and tubers from cut haulm. This mechanism has separating member installed after elevator, fruit separator which has at least one drum installed for rotation and provided with projecting pins on its cylindrical surface. Harvester has also separating device in form of dossor and brush, cross, longitudinal and discharge conveyors, pressing device in form of rigid material aprons with flexible lower part pointed towards drums. Pressing device is located over drum housings and is installed with clearance decreasing in direction from elevator. Clearance can be adjusted as necessary. Pressing device has plate curved towards drum and installed with minimum clearance between plate and drum housing, as compared with clearance between aprons and drums. Slotted plate of pressing device is hinge-mounted on frame and is spring-loaded at elevator side. Separating group of harvester is formed by dossor and brush. Intake portion of dossor is located under tail portion of elevator. Upper dossor tension mechanism is located farther under slot formed by extreme rod of elevator and member for separating to side from elevator. Tail portion of dossor is pointed towards brush rotating in opposite direction. Device for forced loading of separated products is installed in zone of pin dossor tensioning mechanism . Forced loading device is made in form of longitudinal conveyor with device for adjusting conveyor belt inclination relative to horizon. Initial portion of longitudinal conveyor at side of separating member is arranged lower than horizontal axis of conveyor and higher than pins of pin dossor. Fan is installed below longitudinal rod conveyor. Its suction line can be directed towards rod surface of cross conveyor, and discharge line, towards end portion of longitudinal conveyor. Pinned roll is installed between tail section of elevator and intake portion of pin dossor. Pins of roll get into pin spaces of pin dossor. EFFECT: increased capacity and reliability, improved quality of operation of separating groups.
Patent RU-94021532-A (RU)
Inventor: DOROZHKIN A K
IPC: C22C1/08
Filed: 1994-06-10
Abstract: FIELD: electrical engineering. SUBSTANCE: method including pressing of porous Ag-Cd stock, internal oxidation, caking, calibration, and high-temperature baking is distinguished with that, for pressing, Ag-Cd alloy powders with particle size 2-7 mcm are used and pressure value is 1.5-2.3 Ts/cu. cm, oxidation temperature is 280- 400 C, and that of final baking 860-900 C. Method results in increased wear resistance and elimination of interpole linkage, which gives rise either to increasing service life of actuators by some 50% with the same amount of silver or to 1.5-fold decrease in contact weight. EFFECT: increased reliability and service life of contacts.
Patent RU-94025645-A (RU)
Inventor: MAKUSHIN V D
IPC: A61B17/56
Filed: 1994-07-08
Abstract: FIELD: medicine. SUBSTANCE: method involves applying Ilisarov apparatus to treat the extremity. Longitudinal split piece of the fibia is formed in oblique sagittal plane from the cuts in the fibia projection, the split piece having superior and inferior poles that exceed defect in size. Transverse fibia osteotomy is carried out in the projection of lower split piece pole at the level of fibia deformity apex. Then fibia head is reduced to correction-to-norm state, the split piece is moved close to the tibial fractured fragments in oblique sagittal plane with the foot being rotated. Distraction in its inferior half follows until the shortening is eliminated. EFFECT: enhanced effectiveness of treatment.
Patent RU-94025961-A (RU)
Inventor: SAPRYKIN D N
IPC: D01G15/02
Filed: 1994-07-14
Abstract: FIELD: textile industry, particular, technology and design of carding machines and production of nonwoven textile materials, and spinning. SUBSTANCE: novelty in the offered device consists in that it has two-zone aerodynamic randomizer promoting setting up of transverse and longitudinal vibrations of fibrous layer on the drums to raise the fibers on the drum, change of bulk density of fibrous layer on drum, double turning of fibers with transverse shifting that provides for randomness and at the same time separation of dust and trash from the layer with their subsequent removal by means of aerodynamic traps. EFFECT: improved separation of fibers randomness in produced fiber layer, changed bulk density and multizone dedusting.
Patent RU-94028642-A (RU)
Inventor: OLIV E DAJEZ
IPC: B29D30/06
Filed: 1994-08-08
Abstract: FIELD: rubber industry. SUBSTANCE: pneumatic tyre vulcanizer has loading-unloading device 3 providing for placing tyre in vulcanizing mould 1 and delivering to mould heat energy required for process of vulcanization by means of inductors 42. Vulcanizer has also chamber 5 capable of accommodating several vulcanizing moulds 1 at a time and keeping each mould 1 in isolation from ambient atmosphere to reduce to minimum losses of heat during vulcanization period. EFFECT: enlarged operating capabilities.
Patent RU-94033878-A (RU)
Inventor: BORIMSKIJ A I
IPC: C01B31/06
Filed: 1994-09-15
Abstract: FIELD: production of synthetic diamonds. SUBSTANCE: synthetic diamonds suitable for use in fabricating diamond tools are prepared using an intermediate solvent applying on its surface a relief in the form of alternating protrusions and cavities, said relief having been obtained by melting preliminary compressed powders at a temperature constituting 0.60-0.95 of melting temperature of a component of this material possessing minimal melting temperature. EFFECT: elevated conversion of graphite into diamond, increased uniformity of the product in relation to quality marks and granularity, increased content of coarse crystals, and possible control of the diamond granularity distribution maximum. 1 cl, 1 tbl