baber/WOPTO huggingface dataset:
Patent CY-1123454-T1 (CY)
Title: Πολυπεπτιδια me δυο παρατοπους τα οποια ανταγωνιζονται τη σηματοδοτηση wnt σε κυτταρα ογκων
Inventor: ZINZALLA VITTORIA
IPC: A61K39/00
Filed: 2020-10-12
Abstract: Η εφεύρεση παρέχει καινοφανή πολυπεπτίδια τα οποία έχουν δύο παρατόπους και τα οποία δεσμεύουν διασταυρούμενα LRP5/LRP6, και πιο συγκεκριμένα παρέχει καινοφανή συγκροτήματα μονών μεταβλητών περιοχών ανοσοσφαιρίνης τα οποία συγκροτήματα αντιδρούν διασταυρούμενα με LRP5/LRP6, έχουν δύο παρατόπους καθώς και μπορούν να αναστείλουν μονοπάτια σηματοδότησης Wnt. Η εφεύρεση επίσης σχετίζεται με συγκεκριμένες αλληλουχίες τέτοιων πολυπεπτιδίων, με μεθόδους παραγωγής αυτών, και με μεθόδους χρήσης αυτών, συμπεριλαμβανομένων μεθόδων αγωγής έναντι νόσων όπως είναι ο καρκίνος.
Patent CY-1126103-T1 (CY)
Title: ΣΤΕΡΕΕΣ ΜΟΡΦΕΣ ΚΑΙ ΦΑΡΜΑΚΟΤΕΧΝΙΚΕΣ ΜΟΡΦΕΣ ΤΟΥ(S)-4-(8-AMINO-3-(l-(BOYT-2-YNOΫΛO)ΠYPPOΛΙΔΙΝ-2-YΛO)ΙΜΙΔΑΖΟ[1,5-Α]ΠΥΡΑΖΙΝ-1-ΥΛΟ)-Ν-(ΠΥΡΙΔΙΝ-2-ΥΛΟ)ΒΕΝΖΑΜΙΔΙΟΥ
Inventor: BLATTER FRITZ
IPC: C07D487/04
Filed: 2023-06-01
Abstract: Η παρούσα αίτηση σχετίζεται με μια σύνθεση για χρήση στην αγωγή υπερπολλαπλασιαστικών παθήσεων, με την εν λόγω σύνθεση να περιλαμβάνει μια κρυσταλλική μορφή της ελεύθερης βάσης του (5)-4-(8-αμινο-3-(1-(βουτ-2-υνοϋλο) πυρρολιδιν-2-υλο)ιμιδαζο[1,5-α]πυραζιν-1-υλο)-Ν-(πυριδιν-2-υλο)βενζαμιδίου.
Patent CY-1126133-T1 (CY)
Title: Μπαταρια ροης οξειδοαναγωγης
Inventor: SCHRÖDER PHILIPP
IPC: H01M8/18
Filed: 2023-07-07
Abstract: Μια μπαταρία ροής οξειδοαναγωγής, που περιλαμβάνει μια πρώτη αποθήκη ηλεκτρολύτη (1), μια δεύτερη αποθήκη ηλεκτρολύτη (2), ένα ηλεκτροχημικό κύτταρο συνδεδεμένο με την πρώτη και τη δεύτερη αποθήκη ηλεκτρολύτη (1, 2), όπου το ηλεκτροχημικό κύτταρο περιλαμβάνει μια πρώτη ημι-κυψέλη και μια δεύτερη ημι-κυψέλη, όπου η πρώτη ημι-κυψέλη περιλαμβάνει μια κάθοδο (7), όπου το δεύτερο ημικύτταρο περιλαμβάνει μια άνοδο (8), όπου το πρώτο και το δεύτερο ημικύτταρο διαχωρίζονται μεταξύ τους με μια μεμβράνη ανταλλαγής ιόντων (9), όπου η πρώτη αποθήκη ηλεκτρολύτη περιλαμβάνει ένα υδατικό διάλυμα που περιλαμβάνει ένα συμπλοκο σιδήρου μιας ένωσης του τύπου (Ι) και στερεοϊσομερή της ένωσης του τύπου (Ι).
Patent GR-880300092-T1 (GR)
Title: Vinyl phenol derivatives, their preparation and their use
Inventor: DR WUEST HANS-HEINER
IPC: C07C39/23
Filed: 1988-10-21
Abstract: Vinylphenol derivatives of the formula I   <IMAGE>   where A and R1 to R7 have the meanings stated in claim 1 and in the description, and their physiologically tolerated salts, drugs prepared from these, and their use for the treatment of various disorders of the skin, the mucous membranes and the internal organs, and of rheumatic disorders.
Patent GR-990300018-T1 (GR)
Title: Devices for treating pulmonary vasoconstriction and asthma
Inventor: ZAPOL WARREN M
IPC: A61M13/00
Filed: 1999-01-01
Abstract: A method for treating or preventing bronchoconstriction or reversible pulmonary vasoconstriction in a mammal, which method includes causing the mammal to inhale a therapeutically-effective concentration of gaseous nitric oxide (1,10) or a therapeutically-effective amount of a nitric oxide-releasing compound (106), and an inhaler device (102) containing nitric oxide gas and/or a nitric oxide-releasing compound.
Patent SI-1448741-T1 (SI)
Title: Method of gluing wood based materials
Inventor: PIRHONEN SALME
IPC: C08G8/00
Filed: 2002-10-15
Abstract: The present invention relates to a method of gluing wood based materials by providing an adhesive system onto wood based materials followed by curing, the adhesive system comprises a melaminic amino resin and a phenolic resin composition, wherein the phenolic resin composition comprises an acid and a phenolic resin. The invention also relates to an adhesive system and a stable phenolic resin composition as well as wood based products obtainable by the method or through the use of the adhesive system.
Patent SI-2305245-T1 (SI)
Title: Treatment of diseases associated with the use of antibiotics
Inventor: SHUE YOUE-KONG
IPC: A61P1/00
Filed: 2005-05-13
Abstract: The invention relates to a compound having formula (II), a pharmaceutical composition comprising the compound and the compound for use in treating or preventing a disease in a patient caused by the presence of  Clostridium difficile,  methicillin-resistant  Staphylococcus aureus  (MRSA) or vancomycin-resistant enterococci (VRE).
Patent SI-2024149-T1 (SI)
Title: Device for the rotary stamping of stamped pieces of defined geometry and size from a planar structure and its use
Inventor: MARDIAN FRANZ-JOSEF
IPC: B26F1/00
Filed: 2006-05-11
Abstract: An apparatus for rotational stamping of stamped blanks with a defined geometry and size from a flat material comprises a tool, which comprises plural cutting dies and cutting holes. A first tool support rotates about a first axis and a second tool support rotates about a second axis. The first axis and the second axis are disposed in parallel and at a radial distance from one another, so that a radial offset for forming a pass-through gap for the flat material is provided between the first tool support and the second tool support. The cutting dies penetrate the cutting holes precisely fitting through counteracting rotation of the tool supports. The invention provides that the cutting dies and the cutting holes are disposed respectively on the circumference of the first tool support and on the circumference of the second tool support, in a seamless and alternating pattern, so that the flat material is processed into stamped blanks in a single step without lost or scrap pieces.
Patent SI-2307631-T1 (SI)
Title: Light-weight load-bearing structures reinforced by core elements made of segments
Inventor: HERTZ KRISTIAN
IPC: E04C2/00
Filed: 2009-03-13
Abstract: The invention relates to a light-weight load-bearing structure, reinforced by core elements (2) of a strong material constituting one or more compression or tension zones in the structure to be cast, which core (2) is surrounded by or adjacent to a material of less strength compared to the core (2), where the core (2) is constructed from segments (1) of core elements (2) assembled by means of one or more prestressing elements (4).  The invention further relates to a method of casting of light-weight load-bearing structures, reinforced by core elements (2) of a strong material constituting one or more compression or tension zones in the structure to be cast, which core (2) is surrounded by or adjacent to a material of less strength compared to the core (2), where the core (2) is constructed from segments (1) of core elements (2) assembled and hold together by means of one or more prestressing elements (4).
Patent SI-3079994-T1 (SI)
Title: Device and method for opening containers containing heterogeneous materials
Inventor: CHARREYRE FABIEN MICHEL ALAIN
IPC: B65B69/00
Filed: 2014-12-10
Abstract: Opening containers.
Patent DE-3587160-T2 (DE)
Inventor: WALKER HANS
IPC: C07J17/00
Filed: 1985-04-26
Granted: 1993-09-30
Abstract: The invention relates to the therapeutic use of sterolins and/or spiroketalins as lipoxygenase normalisors of a degenerated leukotriene biosynthesis mechanism, especially in the treatment of allergic (such as asthma) or autoimmune diseases and psoriasis in particular.
Patent DE-3650682-T2 (DE)
Inventor: KOICHIRO OKA
IPC: A61K8/72
Filed: 1986-01-15
Granted: 1998-09-24
Abstract: Organic spherical particles having a cationic group and having an average particle size of 0.1 - 1000  mu m, which particles have adsorbed on the surface one or more selected from a fine particles having an anionic group and negatively chargeable fine particles, and also a process for their production. Where said particles are composed of an epoxy type resin cured with an amine type curing agent, they can satisfactorily adsorb the aforesaid substance. As the result of the adsorption of the aforesaid substance to said particles, the static build-up properties, electrical conductivity, color shade etc. of said particles may be modified, and also it is possible to impart ultraviolet light absorbing ability and to prevent blocking between the particles. These particles may be employed as formulation ingredients for cosmetics, paints, electrostatic copier toners etc.
Patent DE-3687771-T2 (DE)
Inventor: EIGENMANN LUDWIG
IPC: G09F13/22
Filed: 1986-07-11
Granted: 1993-07-08
Abstract: A road surface marking strip (22) comprises spaced transparent protruding elements containing light-emitting diodes -LEDs- (18), and a photosensitive device (12) located on said strip (22) and adapted to cause, when excited by light from the headlights of an approaching vehicle, switching on of the LEDs (18)-Illumination of the marking strip can also be activated by traffic lights, light from the traffic light being transmitted to the photosensitive device via optical fibres. 
<??>Retroreflective elements, e.g. catadioptric prisms, alternate on the strip with the LED containing elements. Further the strip is provided with solar converters located thereon and with storage means for the electric energy generated. 
<??>To better cope with fog conditions, a series of halogen type micro-lamps (20) can be provided on the marking strip (22), in addition to the elements containing the LEDs (18). On the strip a second photosensitive device (14) monitors the light coming from a dedicated LED (16) and causes the fog condition lamps (20) to be switched on when the intensity of the illumination perceived drops below a safe level. 
<??>To provide a warning of potentially icy road conditions, the surface of the marking strip can contain cholesteric liquid crystals to change color when temperature drops below a certain point, a LED illuminating the warning surface.- Alternatively, the strip can be illuminated by a colored ice alert LED controlled by a temperature sensor.
Patent DE-3688188-T2 (DE)
Inventor: FUJIOKA KEIJI
IPC: A61K9/22
Filed: 1986-12-23
Granted: 1993-10-14
Abstract: Described is a method for preparing a sustained release formulation utiliing collagen and/or gelatin as a carrier, which comprises the steps: 
 
  (i) preparing a uniform and high concentrated mixture with respect to the collagen and/or gelatin by blending an active ingredient, said collagen and/or gelatin, and water or an admixture consisting of water and a hydrophilic organic solvent under one of the conditions selected from: 
 
  (A) the pH of the mixture is kept below 5 and the salt concentration of the mixture is retained below fiber-forming concentration; 
  (B) chemically modified collagen and/or gelatin is employed; and 
  (C) glucose is added to the mixture; 
 
  (ii) molding the resultant mixture; and 
  (iii) gradually eliminating the solvent from the molded product.
Patent DE-3688259-T2 (DE)
Inventor: MINTZ MICHAEL D
IPC: A61B17/32
Filed: 1986-02-17
Granted: 1993-07-29
Abstract: An apparatus is provided for implementing a standardized skin incision which apparatus includes a housing (14) having a base containing an elongated slot (21). The base is adapted to be held flush against a patient's skin prior to making an incision. The housing (14) has an internal hollow (30) which contains a pivot arm (60) having a first pivotal end and a second end having a cam follower (61). Located within the housing is a cam surface (50) upon which the cam follower (61) of the pivot arm (60) rides. The pivot end of the arm (60) contains a cutting edge (71) and is coupled to the housing such that it is enabled to move transversely while pivoting. The cam surface (50) which is a convoluted surface controls the path of the pivot arm (60) and therefore controls the path of the cutting edge (71) as it enters the slot (21) when triggered. The device produces a standard incision of a given length and a given depth as controlled by the reciprocating pivot point and the cam surface. The device is completely disposable and further possesses the advantage that the cutting edge (71) is always located within the housing (14) except when the unit is triggered where the edge (71) traverses and projects through the slot (21) in the housing (14) for an extremely short period of time. The unit can be fabricated from plastic and sterilized prior to use and hence it is completely disposable.
Patent DE-3780674-T2 (DE)
Inventor: SHU LARRY S
IPC: C09K21/14
Filed: 1987-03-31
Granted: 1992-12-10
Abstract: Fireproofing compositions for steel structural members comprise a hydratable cementitious binder, shredded polystyrene aggregate, an air entraining agent, and a fibrous material. On addition of water, the compositions form settable, sprayable slurries which can be pumped to the point of application. The slurries are capable of spray application to steel structural members and adhere to the member in the slurried state and after setting. Excellent fire and heat protection is provided to the member despite the organic nature of the polystyrene aggregate.
Patent TR-199900309-T2 (TR)
Inventor: KLAUER HEINZ DIETER
IPC: E04B2/86
Filed: 1997-07-23
Abstract: Mesafe koruyucu mesnetlerle (Q) birbirlerine bagli olan iki yalitim levhali bir yalitim elemani için, en azindan mesafe koruyucu mesnetlerin (Q) içinde, levhalarin arasina konulmus olan dolgu malzemesine karsi kapali olan bir uçtan digerine dogru boylu boyunca uzanan bir deligin öngörülmesi önerilmektedir. Bu türden yalitim elemanlariyla yapilacak olan bir duvar insaati esnasinda, örnegin dogrultma raylari/kilavuzlari (R/S) gibi stabilizasyon unsurlari uzunlamasina deliklerin içinde bulunan ve duvarin arasindan ulasan baglanti elemanlari (G) vasitasiyla sabitlenebilip gergin bir hale getirilebilirler. Baglanti elemanlari (G) yeniden kolaylikla uzaklastirilabilirler. Yalitim elemanlari tercihen ayri üretilmis olan yalitim levhalarindan ve bunlarin içine itilen mesafe koruyuculardan (Q) meydana gelmektedir.
Patent TR-199900509-T2 (TR)
Inventor: SMAHOVSKY VENDEL
IPC: C07D401/12
Filed: 1997-09-08
Abstract: Bulus
Patent TR-199901564-T2 (TR)
Inventor: ITOH AKINORI
IPC: A61K9/50
Filed: 1997-11-20
Abstract: Hizli çözülebilen ve tat maskelendirici ispençiyari dozaj formu aktif karisim ihtiva eden çekirdek, düsük sübsitüte edilmis hidroksipiropil selülöz, ve mikrokristalin selülöz, çekirdek toplam agirliginin en az %26.0'i mikrokristalin selülözden olusan; ve çekirdek, suda çözülebilir polimer ihtiva eden çekirdek üzerinde olusturulmus iç saran tabaka; tükürükte çözülmeyen polimer ihtiva eden iç saran tabakanin üzerinde olusturulmus dis saran tabakadan olusmaktir. Böyle bir oral dozaj formu hazirlanmasini saglayan islem açiklanmistir.
Patent DE-60013524-T2 (DE)
Inventor: MCMURTRY DAVID ROBERTS
IPC: B23Q17/22
Filed: 2000-09-22
Granted: 2005-02-03
Abstract: A probe arm comprises a base member 10 securable to a surface of a machine tool, and a rotatable hub 12, carrying an arm member 16 with a tool-setting probe (18 Fig 1). The hub has a portion 22 with three radial projections (26 Fig 2) which rotates within an aperture 24 of the base which also has three inward radial projections 30. Together these projections form stops at the operative and non-operative positions of the probe. The aperture also has three axial raised areas 42 on an annular ledge 40 which support an annular should 44 on the hub. Thus there are six points of contact between the hub and base member in the operative and non-operative positions. A biasing arrangement comprises a detent plate 46 secured to the aperture and a planar spring 48 secured to the hub by its central region. Ball bearings 56 are loosely retained in two opposite lugs (54 Fig 6) on the spring and run around the detent plate between two pairs of detent holes (58 Fig 5). In the operative and non-operative positions, the ball bearings rest on radially-extending edges (58A Fig 5) of the detent holes and thus the axial force of the spring also provides a component of force in a tangential direction, thereby causing a rotational force. <IMAGE>
Patent DE-60020731-T2 (DE)
Inventor: CLAUSEN D
IPC: F02M37/22
Filed: 2000-10-18
Granted: 2006-05-04
Abstract: A recirculating valve for the fuel system of an internal combustion engine includes a valve body with a fuel supply passage and a fuel return passage. An air separation chamber and a restricted orifice are provided in the fuel return passage. A pressure valve allows excess heated return fuel in the air separation chamber to recirculate with the fuel in the fuel supply passage. The valve also directs return air back to the tank and prevents the air from passing to the engine. A thermal actuator maintains the pressure valve in a closed condition when the fuel increases above a predetermined temperature. A relief valve can be provided in the fuel return outlet port to allow fuel to easily pass back to tank during normal operating conditions.
Patent DE-60021254-T2 (DE)
Inventor: BRYANT M
IPC: A61K31/341
Filed: 2000-03-15
Granted: 2006-04-20
Abstract: The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.
Patent DE-60021497-T2 (DE)
Inventor: FIDOCK MARK DAVID
IPC: A61K38/46
Filed: 2000-09-14
Granted: 2006-05-18
Abstract: Amino acid sequences and nucleotide sequences relating to PDEXV are described. In a preferred aspect, the amino acid sequence comprises the sequence presented as SEQ ID No. 1.
Patent DE-60029609-T2 (DE)
Inventor: SILVERBROOK KIA
IPC: G08C21/00
Filed: 2000-05-24
Granted: 2007-07-19
Abstract: A method for providing interactivity for printed content is disclosed. An image of a writing surface containing the printed content is captured by an optical imaging pen device. The image includes a pattern printed on the writing surface. A plurality of available options associated with the printed content coincident with the pattern in the image is then determined and a selection from a user of one of the plurality of available options is received. An application is executed, with the execution using the selected option.
Patent DE-60032783-T2 (DE)
Inventor: DUFFY J
IPC: C07D403/12
Filed: 2000-09-22
Granted: 2007-12-06
Abstract: Invented are non-peptide TPO mimetics. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected azo-pyrazole derivative.
Patent DE-60037751-T2 (DE)
Inventor: CARETTA RENATO
IPC: B60C11/03
Filed: 2000-11-29
Granted: 2009-01-15
Abstract: A tire for a wheel of a vehicle includes a casing structure, a belt structure, and a tread band. A tread band pattern includes a central zone, two intermediate zones, and two shoulder zones. Each of the zones extends between planes that are substantially parallel to an equatorial plane of the tire. Each intermediate zone includes first and second sequences of pairs of transversal grooves. The first sequence pairs are alternated with the second sequence pairs. The grooves of the two sequences are inclined relative to each other. The first sequence grooves extend from first ends, at respective axially intermediate planes, to second ends, at predetermined first distances from selected second sequence grooves. The second sequence grooves extend from third ends, at respective axially inner planes, to fourth ends, at predetermined second distances from selected first sequence grooves. Intermediate zones include a zigzag rib. Shoulder zones include additional transversal grooves.
Patent DE-60102078-T2 (DE)
Inventor: KRILL STEFFEN
IPC: C07C69/157
Filed: 2001-03-24
Granted: 2004-12-23
Abstract: A process for preparing trimethylhydroquinone diacetate, with subsequent hydrolysis to give trimethylhydroquinone, the process including reacting 2,2,6-trimethylcyclohexane-1,4-dione under oxidative conditions, in the presence of a sulfonating agent and a strong acid, and in the presence of an acylating agent.
Patent DE-60102597-T2 (DE)
Inventor: WEULERSSE JEAN-MARC
IPC: H01L21/027
Filed: 2001-09-19
Granted: 2005-03-03
Abstract: This device comprises at least three pulsed lasers (2, 4, 6), in order to supply light pulses, and means (14) for directing these pulses substantially onto the same spot of a target (16) and substantially at the same time onto this spot. The lasers are pumped by diodes (40) operating continuously.
Patent DE-60103744-T2 (DE)
Inventor: ZDEBLICK A
IPC: A61B17/88
Filed: 2001-02-16
Granted: 2005-07-21
Abstract: Surgical techniques and instruments are provided for performing laparoscopic surgical procedures. The apparatus (45) includes a sleeve (100) having a proximal end (104), a distal end (102), and a lumen (106) extending between the proximal and distal ends. The lumen (106) opens at the proximal end (104) and receives an elongated member, such as a cannula or surgical instrument, therethrough. The sleeve (100) is resilient material and conformable to the outer shape of at least a distal portion of the elongate member. In one form the distal end wall includes means for opening the end wall to allow the elongate member to advance therethrough. The sleeve (100) may also be provided with internal ribs (110) and a flange member. Various techniques using various surgical instruments in laparoscopic procedures are also disclosed. <IMAGE>
Patent DE-60106168-T2 (DE)
Inventor: IMOTO MASAHIRO
IPC: A61P9/10
Filed: 2001-04-20
Granted: 2005-10-13
Abstract: There is provided heterocyclic compounds of the following formula (I):  in which, A is optionally substituted alkyl group, optionally substituted aryl group or optionally substituted heterocyclic group; B1 and B2 are, hydrogen atom, alkyl group or hydroxyl group; or combined together to represent carbonyl group; X is oxygen atom, sulfur atom, carbon atom or nitrogen atom; dotted line shows either presence or absence of bond; n is integer of 1 or 2; and the group -X-Y- represents optionally substituted alkylene or cyclic alkenylene bond; or a pharmaceutically acceptable salt thereof. These compounds have good affinity for alpha4beta2 nicotinic acetylcholine receptors and activate the same to thereby exert a preventive or therapeutic effect on cerebral dysfunction.
Patent DE-60107445-T2 (DE)
Inventor: HOCHWALT A
IPC: A61L9/01
Filed: 2001-09-06
Granted: 2005-04-07
Abstract: Novel compositions and methods for reducing odor. The composition comprises at least one synthetic zeolite, at least one acid and at least one substance selected from a metal oxide, metal, or salt of a metal or metal oxide. A wide range of odors, including ammonia and sulfurous odors, may be controlled by contacting an effective amount of the above composition with the article, substance or environment that emits the undesired odor. The composition may also be incorporated into other substances for odor reduction or control to form odor-controlled articles.
Patent DE-60112175-T2 (DE)
Inventor: CLARK BRUCE D
IPC: H01F7/08
Filed: 2001-05-01
Granted: 2006-05-24
Abstract: Proportional solenoids have low friction bearings formed by molding a pair of annular bearings in imprecise grooves formed in armatures so that radially outer surfaces of the bearings have a precise and low friction fit within precision machined interiors of solenoid housings. The bearings can be formed on body or push rod portions of the armatures and can have different outside diameters that are formed in a single precision mold to ensure concentricity and accuracy without requiring precision machining of armature or bearing surfaces.
Patent DE-60113807-T2 (DE)
Inventor: SHOA A ABDUL RAHMAN
IPC: A61K31/435
Filed: 2001-01-29
Granted: 2006-07-13
Abstract: Compositions for the prophylactic or therapeutic treatment of bacterial diseases in humans and animals, comprising as essential active ingredients a quinolone- or naphtyridone-type antibiotic or an active chemical derivative thereof and bromhexine-HCl, glacial acetic acid, water and a stabilizing agent. The compositions are stable upon storage over a broad range of temperature. The invention concerns also the combined use of a quinolone- or naphtyridone-type antibiotic or an active chemical derivative thereof and bromhexine-HCl for the treatment of bacterial infections in humans and animals, and a process for the preparation of the aforementioned compositions.