baber/WOPTO huggingface dataset:
Patent PT-106051-A (PT)
Title: Pró-fármacos do ácido pirazinóico activados por esterases de micobactérias
Inventor: CONSTANTINO LUIS FILIPE VICENTE
IPC: A61K31/4965
Filed: 2011-12-09
Abstract: UMA VEZ QUE A PIRAZINAMIDA É UM PRÓ-FÁRMACO DO ÁCIDO PIRAZINÓICO, OUTROS PRÓ-FÁRMACOS DO ÁCIDO PIRAZINÓICO PODERÃO POSSUIR ACTIVIDADE CONTRA M. TUBERCULOSIS. ESTES COMPOSTOS DEVEM SER RESISTENTES AO PLASMA HUMANO E A ENZIMAS DO FÍGADO, MAS DEVEM SER FACILMENTE HIDROLISADOS, POR MICOBACTÉRIAS NO LOCAL DE ACÇÃO. OS ÉSTERES FORAM PROPOSTOS NO PASSADO, COMO PRÓ-FÁRMACOS DO ÁCIDO PIRAZINÓICO. A PRINCIPAL VANTAGEM DESTES COMPOSTOS É QUE ELES NÃO SÃO ACTIVADOS POR UMA ENZIMA ESPECÍFICA (PIRAZINAMIDASE), MAS POR UMA VASTA GAMA DE ESTERASES O QUE IMPEDE O APARECIMENTO DE RESISTÊNCIA POR ESTE MECANISMO. ESTES COMPOSTOS DEVEM NO ENTANTO CHEGAR À MICOBACTÉRIA NA FORMA DE PRÓ-FÁRMACO, POIS CASO CONTRÁRIO TERÃO DIFICULDADE EM PENETRAR NA PAREDE MICOBACTERIANA E UMA VEZ QUE O PLASMA TAMBÉM TEM ESTERASES, OS COMPOSTOS ESTUDADOS PODERÃO SER RAPIDAMENTE HIDROLISADOS. PRÓ-FÁRMACOS COM A FUNÇÃO AMIDA SÃO RESISTENTES À HIDRÓLISE NO PLASMA, NO ENTANTO, OS COMPOSTOS PODERÃO NÃO SER ACTIVADOS DE FORMA EFICIENTE PELAS ESTERASES MICOBACTERIANAS E NÃO APRESENTAM ACTIVIDADE. NOVOS ÉSTERES RAMIFICADOS LIPOFÍLICOS FORAM SINTETIZADOS COM O FIM DE RETARDAR A SUA HIDRÓLISE PELO PLASMA HUMANO E PELO FÍGADO ANTES DE ATINGIR AS MICOBACTÉRIAS ALVO. A SUA CONSTANTE DE VELOCIDADE DE PSEUDO-PRIMEIRA ORDEM PARA A HIDRÓLISE NO PLASMA HUMANO FOI AVALIADA ASSIM COMO A SUA ACTIVIDADE CONTRA M. TUBERCULOSIS H37RA. A RAMIFICAÇÃO NO PRIMEIRO CARBONO ALCOXÍLICO, ADJACENTE À FUNÇÃO ÉSTER, INESPERADAMENTE AUMENTOU A ESTABILIDADE AO MESMO TEMPO QUE MANTEVE A ACTIVIDADE. A BOA ESTABILIDADE DESTES COMPOSTOS JUNTAMENTE COM A SUA ACTIVIDADE CONTRA M. TUBERCULOSIS FORAM AS PRINCIPAIS REALIZAÇÕES DA PRESENTE INVENÇÃO.
Patent PT-116952-A (PT)
Title: Distribuidor de limites de taxa de carga para a admissão de solicitações de serviço discretos
Inventor: JOÃO PEDRO GOMES RODRIGUES
Filed: 2020-12-16
Abstract: A PRESENTE INVENÇÃO FORNECE UM APARELHO DISTRIBUIDOR DE LIMITES DE TAXA DE CARGA (600) PARA UM SISTEMA DE PROCESSAMENTO DE DADOS (100), COM A ADMISSÃO (620) DE SOLICITAÇÕES DE EVENTOS DE SERVIÇO (610) LIMITADA PELA APLICAÇÃO DE LIMITES DE TAXA DE CARGA (340) DETERMINADA POR UM ALGORITMO DE DISTRIBUIÇÃO JUSTA DE DESCARTE. O ALGORITMO GARANTE DE FORMA DETERMINÍSTICA A PREVENÇÃO DE SOBRECARGAS, NUNCA ULTRAPASSANDO A CAPACIDADE TOTAL DE PROCESSAMENTO DO SISTEMA (100) NA ATRIBUIÇÃO DOS LIMITES DA TAXA DE CARREGAMENTO. ESTE ALGORITMO CALCULA OS LIMITES DE TAXA DE CARGA (340) A SEREM ATRIBUÍDOS ÀS RESPETIVAS INTERFACES DE SOLICITAÇÕES DE SERVIÇO, DE MODO QUE SEJAM DESCARTADAS AS SOLICITAÇÕES DE EVENTOS DE SERVIÇO (610), EM SITUAÇÕES DE SOBRECARGA, PELAS DIFERENTES INTERFACES PROPORCIONALMENTE, COM BASE NUMA CONFIGURAÇÃO QUE PERMITE O CONTROLO DOS CRITÉRIOS APLICADOS.
Patent RU-94023736-A (RU)
Inventor: VAJNERMAN E S
IPC: A23L21/10
Filed: 1994-06-23
Abstract: FIELD: food-processing industry. SUBSTANCE: method involves preparing 40-50%-aqueous dispersion of collagen preparation obtained by treating collagen-containing raw material of agricultural animals, poultry and fish with alkali. To do that, dry collagen preparation is allowed to swell, then heated to 60-65 C while being mixed for 20-30 min. Obtained homogeneous dispersion of gelatinizer is mixed in predetermined weight ratios with preliminarily prepared receipt composition so that collagen preparation concentration is 7-30% of total weight of gelatinized mixture. Obtained gelatinized mass is heated at temperature range of 35-98 C for 10-30 min, formed and cooled to 4-25 C. Depending on gelatinized mass preparation and cooling conditions, gelatinized mass liquid state loss time is 20-40 min. EFFECT: wider raw material base of protein gelatinizers, reduced base product cost, provision for obtaining gelatinized products with regulated physical-mechanical properties.
Patent RU-94025741-A (RU)
Inventor: ZIGANSHIN G K
IPC: C10G21/00
Filed: 1994-07-11
Abstract: FIELD: chemical technology. SUBSTANCE: method is carried out in counterflow regime. Raw materials being fed into medium area of extractor is brought into contact with solvent being fed on upper theoretical plate of extractor, said contact takes place in the presence of antisolvent being fed on lower theoretical plate of said extractor. The process is followed by regeneration of solvent from extract and refined solution and by preparing of refine and extract. Refined solution being prepared after said regeneration is distilled, steam phase is condensed and cooled to prepare the former fraction of said refine. Portion of thus prepared fraction is fed on the second theoretical plate of extractor at temperature being not more than temperature of supply of raw materials into said extractor. The second fraction of refined solution is prepared of liquid phase being produced after distillation of said refined solution. EFFECT: improves quality of refined solution, improves efficiency of method.
Patent RU-94036675-A (RU)
Inventor: MAREICHEV A V
IPC: C02F1/40
Filed: 1994-09-29
Abstract: FIELD: cleaning of water. SUBSTANCE: method involves directing contaminated water and separating water flow into effluent water flow and fatty substance flow by pressure supplied through at least two layers of granular charge, with charge layers being separated by zones free of granular charge and adapted to consolidate fatty substance and recover granular charge by increased water flow pressure. Contaminated water is primarily directed into first U-shaped layer with small-sized grains in upward and then downward direction. EFFECT: increased efficiency and improved quality of water.
Patent RU-94041597-A (RU)
Inventor: SAMOKHVALOV V A
IPC: E01F13/00
Filed: 1994-11-15
Abstract: FIELD: road control. SUBSTANCE: invention refers to facilities laying obstacles to advancement of motor vehicles. Facility composed of set of crossing plates 1 jointed in crossing points and by ends of axles 2 on which tenons 3 directed vertically upwards are put is installed across traffic lane. Slipping rings 4 with holes are put on tenons 3. Ends of soft wire 5 pass through hole in axle 2 of joint, through uniaxial holes in tenons 3 arranged above and through slipping ring 4 put on tenon in this place are tightened in the form loop pulling base of tenon 3 to axle 2 of joint. EFFECT: provision of rigid registration of tenon in blocking facility up to moment of running of tyre of motor vehicle against it and face leaving of tenon off blocking facility after its implantation into tyre. 2 dwg
Patent RU-94044693-A (RU)
Inventor: RYKOV V B
IPC: A01B49/06
Filed: 1994-12-19
Abstract: FIELD: agricultural engineering; machines and devices. SUBSTANCE: device has frame which mounts hoppers for supercompost with distributors and series connected spreader, subsurface cultivating working member with material conduit and dispenser, and roll on disks of which teeth are arranged over radius. Teeth are made in form of equilateral trihedral pyramid whose ribs and faces are made concave. Spreader is made in form of hollow cone with cylindrical ring section in upper portion and elliptical ring section in lower portion whose larger axis is located in cross-vertical plane. With applicator operating, supercompost is uniformly distributed by spreader over surface of soil and, after passing of roll, it gets into holes formed by teeth and subsurface cultivating member with dispenser along furrow bottom. EFFECT: uniform distribution of supercompost in depth of soil. 5 dwg
Patent RU-94044931-A (RU)
Inventor: SKOROBOGATOVA A N
IPC: G01B11/26
Filed: 1994-12-28
Abstract: FIELD: technical measurement in mechanical engineering; check of holes located at distance from each other for axial misalignment. SUBSTANCE: method consists in matching light beam with axis of holes, considering this beam to be a bench mark and determining deflection of axes of holes being checked from bench mark by means of centered optoelectric converters connected with recording unit. Device for realization of this method has laser radiator mounted in adjusting mechanism, optoelectric converters connected with recording unit mounted removably in centering devices and device for motion. Centering devices are placed in holes being checked; one leg of each of them is made for flexibly changing its length; through taper hole of housing is used to receive taper housing of optoelectric converter. Device for motion is secured on end surface of hole being checked and is made in the form of threaded joint of movable and immovable rings. EFFECT: enhanced accuracy of check; possibility to estimate change of form and geometric sizes. 8 cl, 3 dwg
Patent RU-95100339-A (RU)
Inventor: ALKHIMOV A B
IPC: B05B17/06
Filed: 1995-01-16
Abstract: FIELD: engine engineering. SUBSTANCE: ultrasonic spryer consists of ultrasonic converter, concentrator, and mixing chamber mounted at the end of the concentrator. The mixing chamber is provided with branch pipes for supplying a liquid to be sprayed and branch pipe for supplying transporting gas. There is the outlet branch pipe to discharge sol of the liquid to be sprayed. The outlet branch pipe as well as mixing chamber is activated with ultrasonic . EFFECT: enhanced efficiency.
Patent RU-95101859-A (RU)
Inventor: PERE DALMASES BARKHOAN
IPC: A61K31/41
Filed: 1995-02-10
Abstract: FIELD: pharmaceutical industry. SUBSTANCE: invention describes process for preparing 3-{ 2-[4-(6-fluorobenzo[d] isoxazole-3-yl) piperidin-1-yl] ethyl)-2-methyl-6, 7,8,9-tetrahydro-4H-pyriodo[d]pyrimidin-4-one of general formula l by reacting 3-(aminoethyl)-2methyl-6,7,8,9-tetrahydro-4H-pyrido [1,2-a) pyrimidin-4-one of formula II with compounds of formula III in which Y and Z are the same or different leaving groups, e.g. halogen or alkyl or arysulfonyloxy group in the presence of suitable solvent and base. This compound is useful in pharmaceutical industry since it has antipsychotie properties. Compounds of formulae II and III are intermediate compounds for preparation of the above-mentioned desired product. Compounds of formulae II and III are intermediate compounds for preparation of the desired product mentioned above. EFFECT: improved properties of the pharmaceutical.
Patent RU-95102127-A (RU)
Inventor: VOL NITSKAJA EH M
IPC: E03F9/00
Filed: 1995-02-14
Abstract: FIELD: cleaning pipping. SUBSTANCE: method is based on creating pneumatic pulse sequences of carrier frequency within 1 to 100 Hz and pulse repetition rate being changed in each sequence within limits not exceeding carrier frequency in combination with washing out heaps of deposits by water jets. EFFECT: piping surface cleaning. 1 dwg
Patent RU-95102278-A (RU)
Inventor: GOLIKOV V P
IPC: B63B32/20
Filed: 1995-02-17
Abstract: FIELD: water skiing. SUBSTANCE: water skis set in motion by man power consist of two floats 14 with propulsive gates 15, two inner guides 2 and two outer guides 5 over which two floats and two propelling devices with propulsive gates move respectively, two clamps and two sticks connected respectively with floats and propelling devices. Clamps are secured to footgear and sticks are grasped by water skier's hands who also rests against bearing clamp. Float located in front is coupled with guides by means of retainer. Braking and turning of device is effected by locking the gates of propelling devices in open position by means of sticks and braking stops. Speed of skier will be increased at intensive work not only of feet but also hands. EFFECT: high speed of skiing. 1 dwg
Patent RU-95102492-A (RU)
Inventor: IVANOV A A
IPC: B32B3/30
Filed: 1995-02-22
Abstract: FIELD: typical member and method of manufacture from it of cellular fillers which serve as the core in thee-ply panels and shells applicable in various industries, particular, in manufacture of panels for articles of furniture, construction, aviation, radio engineering, ship building and other industries. SUBSTANCE: cellular fillers are produced from any material with maximum mechanical characteristics and cells of triangle and rectangular in shape. Cellular filler are produced in form of shells and used in production of sheet material in form of corrugated board. EFFECT: higher efficiency. 8 cl, 27 dwg
Patent RU-95106298-A (RU)
Inventor: NEKRASOV S G
IPC: B02C19/18
Filed: 1995-04-20
Abstract: FIELD: varnish and dye engineering. SUBSTANCE: invention refers to arrangements for superfine pulverization of finely dispersed materials in liquid media. Apparatus contains a chamber with inlet and outlet fittings and a high-amplitude attachment of ultrasound vibrator. The latter is mounted in spaced relation to chamber body to form a flowing channel, its dimensions in conjunction with its cross-section area providing dispersion of solid phase of varnish and dye suspensions when they flow through flowing channel. Design features of ultrasound vibrator are also precised to ensure a stable level of the aforesaid attachment vibrations and therefore a high quality of treating material. EFFECT: improved design of apparatus and enhanced efficiency of process.
Patent RU-95108394-A (RU)
Inventor: KROTIK I A
IPC: C08J7/16
Filed: 1995-05-23
Abstract: FIELD: rubber industry. SUBSTANCE: invention concerns modifying rubber articles, for example, consolidation in glow discharge in plasma- chemical reactor. Invention increases depth of monomer layer to 0.1- 0.6 mm, improves bonding of layer with base, reduces modification process time to 30-15 min, increases resistance of rubber articles to heat aging, and eliminates damaging ozone layer of Earth owing to introduction into rubber formula of a monomer compatible with gaseous working agent. As fluorine-containing substance, fluoroalcohol is used which, prior to be introduced into rubber formulation, is preliminarily mixed with crude rubber when industrial rubber articles are fabricated, and, to prepare working agent, fluoroalcohol is heated to be evaporated in interelectrode space. When degasification and modification processes are run, constant parameters are ensured: underpressure 0.133-13.3 Pa and specific power of high-frequency discharge 5-15 kW/cu.m. EFFECT: improved quality of produce and enhanced efficiency of process.
Patent RU-95111475-A (RU)
Inventor: TSYMBAL V P
IPC: C22C35/00
Filed: 1995-07-04
Abstract: FIELD: metallurgy. SUBSTANCE: alloy containing silicon, manganese, iron and carbon has additionally barium at the following ratio of components, wt. -%: manganese 55-70; silicon 12-18; carbon 1-3; barium 0.3-1.5, and iron - the rest. The proposed alloy can contain the following concomitants, wt.-%: sulfur 0.01-0.03; phosphorus 0.1-0.4, and copper 0.02-0.04. Ratio manganese : silicon is maintained at the range 3.8-4.6. EFFECT: enhanced quality of alloy and rolled products.
Patent TW-200300481-A (TW)
Title: Temperature-control method of a screwed-type vacuum pump
Inventor: KRIEHN HARTMUT
IPC: F04C29/04
Filed: 2002-11-14
Abstract: This invention relates to a method to adjust the temperature of a screw-type vacuum-pump (1); in order to attain that the pump will not change greatly its property in thermal loading, it is suggested that the cooling is adjusted according to the operation-state of the screw-type vacuum-pump (1), preferably at a constant pump-gap (4).
Patent TW-200303309-A (TW)
Title: Novel n-[4-(1h-imidazol-1-yl)-2-fluorophenyl]-3-trifluoromethyl)-1h-pyrazole-5-carboxamides as factor Xa inhibitors
Inventor: QUAN MIMI L
IPC: A61P9/00
Filed: 2002-11-20
Abstract: The present application describes N-[4-(lH-imidazol-l-yl)-2-fluorophenyl]-3-(trifluoromethyl)-lH-pyrazole-5-carboxamides and derivatives thereof of, which are useful as inhibitors of factor Xa.
Patent TW-200408793-A (TW)
Title: Object surface 3-D contour measurement method and system
Inventor: SUNG HSIN-YUEH
IPC: G01B11/25
Filed: 2002-11-22
Abstract: The present invention provides an object surface 3-D contour measurement method and system, comprising: a projection device capable of projecting a fringe pattern for projecting the pattern onto the object under test; using multi-threaded electro-optical sensor imaging system, projection device of fringe pattern, and relative position shift of object under test to achieve the purposes of both taking image and fringe pattern phase shift, wherein suitable inclined angle and brightness calibration of sensor are applied, if required, to increase the precision degree; obtaining the light strength modulation image caused by the unevenness of the object surface by the multi-threaded electro-optical sensor imaging system; and finally obtaining the unevenness profile of the object surface with respect to a reference plane by a phase shift interferometry analysis method and the geometric relation of projection light source. With this measurement method to measure the 3-D contour of object surface, in addition to that the resolution can reach a precision degree same as the conventional phase shift manner, it has the advantages of high speed and being able to apply to on-line detection in industry use.
Patent TW-200308006-A (TW)
Title: Integrated pressure sensor for measuring multi-axis pressure gradients
Inventor: RANGARAJAN BHARATH
IPC: B24B49/10
Filed: 2002-12-26
Abstract: A system for characterizing a chemical mechanical polishing process is provided. The system includes a wafer that has a metal, polysilicon, and/or dielectric layer and/or substrate and electrical resistance member(s) and/or electrical resistance entities located in and/or on the metal, polysilicon and/or dielectric layer and/or substrate. The system also includes a electrical resistance monitoring system that can read the wafer electrical resistance(s) from the electrical resistance member(s) and/or electrical resistance entities and that can determine wafer stress(es) based upon the electrical resistance(s) to characterize the chemical mechanical polishing process. Such characterization includes producing information concerning relationships between wafer electrical resistance(s) and polishing rate, polishing uniformity and introduction of defects during polishing. Such relationships are correlated with wafer electrical resistance(s) (e.g., wafer stress(es)) as related to parameters like polishing time, pressure, speed, slurry properties and wafer/metal layer properties.
Patent TW-200412592-A (TW)
Title: Manufacturing method to associate solid immersion lens and nanometer aperture, and device thereof
Inventor: HSU WEN-SYANG
IPC: G02B3/00
Filed: 2003-01-09
Abstract: The present invention relates to a manufacturing method to associate solid immersion lens (SIL) and nanometer aperture, and device thereof. It comprises depositing a sacrificial layer on the substrate; coating photoresist on the sacrificial layer and forming an aperture on the photoresist by photolithography technology; applying photoresist reflow and etching to remove the sacrificial layer under the aperture; depositing a conductive material on the photoresist; and performing electroplating to reduce the diameter of the aperture; then coating the other photoresist and forming a pillar-like photoresist structure on the aperture, reflowing the pillar-like photoresist at high temperature to form a micro-lens; and removing the substrate finally to obtain an optical read/write device associating the SIL and nanometer aperture.
Patent TW-200414494-A (TW)
Title: Memiconductor structure having increased quality factor of inductor and process of making the same
Inventor: YEH TZH-JIN
IPC: H01L23/64
Filed: 2003-01-22
Abstract: A semiconductor structure having increased quality factor of inductor and a process of making the same are disclosed. The present invention is featured in that a deep ion implantation region is formed in the substrate and under the shallow trench isolation (STI) region, thereby forming a depletion region in the substrate and around the STI region and the deep ion implantation region. With the use of the present invention, the quality factor can be increased; the substrate capacitive coupling effect can be suppressed; and the depletion region capacitance and the parasitic capacitance can be coupled in series to decrease the total capacitance, thereby increasing the self-resonance frequency.
Patent TW-200307992-A (TW)
Title: Gas heating apparatus for chemical vapor deposition process and semiconductor device fabrication method using the same
Inventor: LIM YOU-DONG
IPC: H01L21/205
Filed: 2003-03-21
Abstract: The present invention provides a gas heating apparatus that activates reaction gases for a chemical vapor deposition. The gas heating apparatus includes a chamber becoming enclosures of the gas heating apparatus; a heat insulating material 20 formed on an inner surface of the chamber so as to thermally insulate the inside of the chamber from the outside; a quartz tube having a gas inflow pipe, a gas outflow pipe, enlarged-pipe portions and abridged-pipe portion, wherein the enlarged-pipe portions and the abridged-pipe portions are alternately repeated and constitute a zigzag shape in an up-and-down direction in the chamber; a plurality of ceramic balls located inside the enlarged-pipe portions of the quartz tube; and a heater having a shape of coil spring and surrounding the zigzag shape of the quartz tube in the chamber.
Patent TW-200419887-A (TW)
Title: Inverter device
Inventor: HATAI AKIRA
IPC: G01R31/00
Filed: 2003-03-31
Abstract: The inverter device of this invention includes a switching control circuit 6a and an electrolytic capacitor's static capacitance computing device 10a. When the power supply source connected to an electrolytic capacitor 5 is cut off, the switching control circuit 6a activates the switching element of a inverter main circuit 7a and causes the electric current to flow through a load so as to cause the electric charge of the electrolytic capacitor 5 to discharge. The electrolytic capacitor's static capacitance computing device 10a computes the static capacitance of the electrolytic capacitor based upon the amount of the discharged electric charge obtained from the output current IC from the electrolytic capacitor 5 and the discharge time, and the voltage drop from the starting of the discharge of the electrolytic capacitor 5, as a discharge voltage ΔV.
Patent TW-200422820-A (TW)
Title: Method and structure of using one basic input/output system (BIOS) memory to start up a computer system
Inventor: WANG CHENG-CHIH
IPC: G06F1/24
Filed: 2003-04-16
Abstract: The present invention is related to a method and structure that use one basic input/output system (BIOS) memory to start up a computer system. The BIOS memory is provided with the first BIOS and the second BIOS. The computer system contains the BIOS memory and one control circuit. The steps of the invented method contains the followings: (a) the control circuit reads the first BIOS in accordance with the first system bus data to start up the computer system; and (b) when the first BIOS is unable to start up the computer system, the control circuit reads the second BIOS based on the second system bus data to start up the computer system.