baber/WOPTO huggingface dataset:
Patent SG-11201407775W-A (SG)
Title: Methods of treating a metabolic syndrome by modulating heat shock protein (hsp) 90-beta
Inventor: NARAIN NIVEN RAJIN
IPC: A61K48/00
Filed: 2013-05-24
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 28 November 2013 (28.11.2013) WIPOIPCT (10) International Publication Number WO 2013/177535 A2 (51) International Patent Classification: A61K 48/00 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/US2013/042692 24 May 2013 (24.05.2013) English English (30) Priority Data: 61/652,023 25 May 2012 (25.05.2012) (84) US (71) Applicant: BERG PHARMA LLC [US/US]; 1845 Elm Hill Pike, Nashville, TN 37210 (US). (72) Inventors: NARAIN, Niven, Rajin; 73 Fresh Pond Park­ way, Cambridge, MA 02138 (US). SARANGARAJAN, Rangaprasad; 45 Central Street, Boylston, MA 01505 (US). VISHNUDAS, Vivek, K.; 91 Stamford Street, Apt. 1, Newton, MA 02466 (US). JING, Enxuan; 200 Maple Street, West Roxbury, MA 02132 (US). (74) Agents: HANLEY, Elizabeth, A. et al.; Mccarter & Eng­ lish, LLP, 265 Franklin Street, Boston, MA 02110 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — without international search report and to be republished upon receipt of that report (Rule 48.2(g)) — with sequence listing part of description (Rule 5.2(a)) (54) Title: METHODS OF TREATING A METABOLIC SYNDROME BY MODULATING HEAT SHOCK PROTEIN (HSP) 90- BETA Delta-Delta Networks DD_NG.vs.HG.vs.HGT 1 ,cys [ NG vs. HG ] vs. [ HS vs. HGT1 ] CJ m i> i> T-H rn T-H O (57) Abstract: The invention provides methods of treatment of metabolic syndrome with HSP90 inhibitors, particularly HSP90P in- ^ hibitors. The invention provides methods of diagnosis and monitoring of metabolic syndrome using HSP90, particularly HSP90p, Q expression and activity level.
Patent SG-11201908006Y-A (SG)
Title: Data transmission method and device
Inventor: LIN YANAN
IPC: H04W28/00
Filed: 2017-03-03
Abstract: Data Transmission Method and Device The present application discloses a method and device for transmitting data, which may 5 obtain frequency diversity gain and further improve reliability of transmission. The method includes: determining a plurality of carriers or carrier groups for transmitting duplicated data according to a plurality of logical channels for carrying the duplicated data, wherein at least two logical channels in the plurality of logical channels correspond to different carriers or carrier groups for transmitting the duplicated data; and transmitting the duplicated data carried in the 10 plurality of logical channels respectively on the plurality of carriers or carrier groups. FIG. 2
Patent HU-183052-B (HU)
Title: Process for the separation of mixtures of fatty acids, fatty alcohols and fatty acid esters into components with different melting points
Inventor: KROLL BENNO
IPC: C07C51/42
Filed: 1980-01-10
Abstract: Verbesserung des in DE-PS 23 17 563 beanspruchten Umnetzverfahrens zur Auftrennung von Fettgemischen in Komponenten unterschiedlicher Schmelzpunkte. 
     Das Trennverfahren wird in zwei hintereinander geschalteten Trennstufen durchgeführt, wobei die in der letzten Trennstufe erhaltene wäßrige Dispersion der höher schmelzenden Fettstoffanteile in die Vakuumverdampfungsstufe der aufgeschmolzenen Fettstoffgemische zurückgeführt wird und dort mit dem wärmeren, noch nicht auf die gewünschte Trenntemperatur abgekühlten Ausgangsmaterial vereinigt wird. 
     Der Vakuumverdampfung in der ersten Trennstufe kann eine Kühlvorrichtung, insbesondere eine Kühlstufe mit Kratzkühlern vorgeschaltet sein, in der 10 - 40 % der insgesamt auszukristallisierenden höherschmelzenden Fettstoffanteile vorkristallisiert werden.
Patent MT-P930-B (MT)
Title: Substained release lithium-containing tablets and method for their manufacture
Inventor: TZIGGER DAVID JOHN
IPC: A61K33/14
Filed: 1983-04-18
Abstract: The release pattern of sustained release lithium carbonate tablets is improved by using a particular form of lithium carbonate material. This should have acicular crystals with a substantially monomodal particle size distribution in which the curve showing volume percentages of particles of different sizes shows a peak at a particle diameter of between 10 and 25  mu m. Moreover not more than 20% by volume of the material should have a particular diameter above 30  mu m. A preferred sustained release agent is a mixture of glyceryl mono-di- and tri-esters of straight chain saturated fatty acids. The tablets may be made by a moist granulation technique, followed by screening to ensure a granulate of appropriate grain sizes, after which the granulate is compacted into tablets.
Patent YU-46126-B (YU)
Title: Raketni uredjaj za mehaničko čišćenje unutrašnjih zidova cevovoda od naslaga kamenca
Inventor: LJ MIRKOVIC
IPC: F16L55/00
Filed: 1982-01-08
Abstract: naznačen time, što se kućište (13) s jednom stranom preko spojnice (17) povezuje s vratilom (16), a sa drugom u sklopu zavojnice (33) sa reznom glavom (26) i što kućište (13) po spoljnjem obimu ima ugradjene mlaznice (14) koje imaju bočne i ugaone otvore (5 i 8) i otvore (10) povezane preko priključka (18) s komorom (25) koja se napaja preko otvora (20) povezanog za priključak (36) koji je ugradjen u valjku (21) na kome su po obimu ugradjeni profilisani nosači (22) za koje su preko klina (4) povezane poluge (2) koje se medjusobno sprežu i povezuju preko klina (30) za nosač (3). Prijava sadrži još 3 patentna zahteva.
Patent AT-403330-B (AT)
Title: Semitone mechanism for a concert harp
IPC: G10D1/04
Filed: 1996-02-05
Granted: 1998-01-26
Abstract: A concert mechanism for concert harps is described. In this, for adjusting the harp tuning, at least one bolt comes to bear in each case on a string and thereby modifies the vibrating length of the latter. The bolt is moved by a rotary-driven setting disc, whilst intermediate members may be provided for transmission between the setting disc and the bolt. The movement of the setting disc is transmitted to the bolt via a slotted guide and, if appropriate, the intermediate members. Two or more bolts may also be provided for each string. The associated drive is preferably of modular design, that is to say can easily be exchanged for another drive. <IMAGE>
Patent HU-183785-B (HU)
Inventor: SONKOLY AUREL
IPC: H03F3/189
Filed: 1982-01-19
Abstract: A találmány tárgya nagylinearitású szélessávú hibrid integrált erősítő kapcsolási elrendezés, amely szerint megvalósított erősítők előnyösen kommunikációs vevőberendezések bemeneti fokozataként, antennaerősítőként stb. alkalmazhatók. A találmány szerinti erősítőnek több szekundertekerccsel kialakított bemeneti teljesítményosztó transzformátora, több primertekerccsel kialakított kimeneti teljesítmény összeadó transzformátora, valamint több visszacsatolt erősítője van, ahol az egyes visszacsatolt erősítők nagyfrekvenciás bemeneti kapcsa a hozzárendelt szekundertekercs egyik kapcsára nagyfrekvenciás kimeneti kapcsa pedig a hozzárendelt primertekercs egyik kapcsára van kötve. A találmány szerinti első megoldás lényege, hogy a viszszacsatolt erősítők számánál eggyel kevesebb számú műveleti erősítője van, az első visszacsatolt erősítő szabályozó bemeneti kapcsára munkapont beállító generátor van kötve, és a további egy vagy több visszacsatolt erősítőhöz viszszacsatolt erősítőként egy műveleti erősítő van hozzárendelve, ahol a műveleti erősítő egyik bemenete a visszacsatolt erősítő szabályozott kimeneti kapcsára van kötve, a műveleti erősítő kimenete a visszacsatolt erősítő szabályozó bemeneti kapcsára van kapcsolva, és a műveleti erősítők másik bemenete közösítetten az első visszacsatolt erősítő szabályozott kimeneti kapcsára van kötve. A találmány szerinti második megoldás lényege, hogy minden egyes visszacsatolt erősítőhöz műveleti erősítő van hozzárendelve, minden egyes műveleti erősítő egyik bemenete a hozzátartozó visszacsatolt erősítő szabályozott kimeneti kapcsára van kötve, minden egyes műveleti erősítő másik bemenete közösítetten referencia feszültségforrás egyik kapcsára van kötve, a műveleti erősítők kimenete a hozzárendelt visszacsatolt erősítők szabályozó bemeneti kapcsára van kapcsolva, és emellett az egyes műveleti erősítők kisfrekvenciás erősítő kialakításúak. A találmány szerinti megoldások előnye, hogy kiemelkedően jó paraméterekkel, főként igen jó másodrendű torzításra vonatkozó jellemzőkkel rendelkező könnyen és kis szériában is olcsón gyártható erősítőt adnak.  1. ábra -1-
Patent HU-184265-B (HU)
Inventor: VEGH GERZSONNE
IPC: C07F9/38
Filed: 1980-04-09
Abstract: A találmány tárgya eljárás 2-bróm-etil-foszfonsav előállítására. A találmány szerint oly módon járnak el, hogy 2-klór-etil-foszfonsav-bisz(2-klór-etil)-észtert 30-60%-os hidrogén-bronüd-oldattal reagáltatnak. -1-
Patent YU-46450-B (YU)
Inventor: ANHAEUSER D
IPC: B65D73/00
Filed: 1988-03-30
Abstract: The invention relates to a removal aid for mechanically detachable substrates adhering to a sheet-like, flexible carrier material and in the form of cuts or predetermined breaking lines in said carrier material. At least in the contact surface of the carrier material is provided for each substrate a separate, non-linear cutting or predetermined breaking line, so that when pressure is exerted on the carrier material with a force component in a direction at right angles to the substrate contact surface a carrier material portion with the substrate portion adhering thereto and bounded by the cutting or predetermined breaking line can be bent in the direction of the substrate or substrates, so that at least part of the substrate in the border area thereof adjacent to the cutting or predetermined breaking line is detached from the carrier material and consequently a gripping portion is formed on the substrate for the complete removal of the latter.
Patent ZA-89116-B (ZA)
Title: Method of making metal matrix composite with the use of a barrier
Inventor: AGHAJANIAN MICHAEL KEVORK
IPC: C04B35/65
Filed: 1989-01-06
Abstract: A net shaped ceramic-reinforced aluminum matrix composite is formed by forming a permeable mass of ceramic material (10) with a defined surface boundary having a barrier, and contacting a molten aluminum-magnesium alloy (20) with the permeable mass of ceramic material (10) in the presence of a gas comprising from about 10 to 100 % nitrogen, by volume, balance nonoxidizing gas, e.g. hydrogen or argon. Under these conditions, the molten alloy (20) spontaneously infiltrates the ceramic mass under normal atmospheric pressures until it reaches the barrier. A solid body of the alloy (20) can be placed adjacent to a permeable bedding of ceramic material (10) having a barrier, and brought to the molten state, preferably to at least about 700 DEG C, in order to form the net shape aluminum matrix composite by infiltration. In addition to magnesium, auxiliary alloying elements may be employed with aluminum. The resulting composite products may contain a discontinuous aluminum nitride phase in the aluminum matrix.
Patent AT-392374-B (AT)
IPC: H02G3/04
Filed: 1988-05-20
Granted: 1991-03-25
Abstract: A cable tray has a lower part 1 and a cover 2 which covers the lower part 1 and whose limbs 6 engage around the outside of the limbs 4 of the lower part 1. A clamping piece 9 is used to attach the cover 2 to the lower part 1 and can be pressed by a screw 11 against the limb 4 of the lower part 1, with the limb 6 on the cover 2 acting as an opposing bearing. This also allows the cover 2 to be attached securely in a higher position than that defined by the spacers 15. <IMAGE>
Patent AT-399266-B (AT)
Title: Withdrawal-guide (runner) fitting
IPC: A47B88/04
Filed: 1990-08-14
Granted: 1995-04-25
Abstract: A withdrawal-guide (runner) fitting for drawers, having a withdrawal rail 2 on the drawer side and a loadbearing rail 1 on the cabinet carcass side on each side of the drawer, load-transmitting running rollers or the like being located between the rails 1, 2. The running rollers are mounted in a carriage 8. A run-out safeguard is provided, which can be overcome when the drawer is pulled out and which prevents the drawer or the withdrawal rails 2 running out when the cabinet carcass is placed at an angle. The run-out safeguard has a hook 9 which is fastened to the loadbearing rail 1, is preferably made of plastic and hooks into the carriage 8 and holds the latter. Integrally moulded onto the carriage 8 is a safeguard attachment 5, which acts on a safeguard tab 6 on the withdrawal rail 2, or integrally moulded on the withdrawal rail 2 is a stud 11, which strikes against a lateral balancing roller 10 on the carriage 8. <IMAGE>
Patent AT-398932-B (AT)
Title: Device for mounting dowels on pins projecting from a mould core
IPC: B28B21/56
Filed: 1990-09-12
Granted: 1995-02-27
Abstract: A device for mounting dowels 9 on pins 8 which project from a mould core 4 of a device for manufacturing moulded concrete parts, has a tool 10 which is movable relative to the mould core 4 for mounting the dowels 9 on the pins 8. The tool 10 has two magazines 11 in which the dowels 9 to be mounted are held available. <IMAGE>
Patent AT-387128-B (AT)
Title: Lifting mechanism for farm tractors
Inventor: SONNTAGBAUER ADOLF ING
IPC: A01B63/102
Filed: 1987-08-25
Granted: 1988-12-12
Abstract: A lifting mechanism for a farm tractor has two lifting arms 7 arranged on a lifting shaft 8. Lifting cylinders engage on the lifting arms 7, and the lifting arms 7 are connected to two lower links via lifting rods. In order to manage with smaller bearings 10 for the lifting shaft 8 and achieve an improved regulating accuracy of the lifting mechanism, the lifting shaft 8 is mounted at its ends 9. Furthermore, the centres of the bearings 10 of the lifting shaft 8 and of the connecting bearings 11, 12 for the lifting cylinders via the lifting rods on the lifting arms 7 lie approximately in a vertical plane E on each side of the tractor. <IMAGE>
Patent AT-390255-B (AT)
Title: Process for the preparation of cis-3-hydroxyproline by trans/cis isomerization of trans-3-hydroxyproline
IPC: C12P13/04
Filed: 1987-09-04
Granted: 1990-04-10
Abstract: cis-3-Hydroxyproline is prepared by oxidizing trans-3- hydroxyproline, which is, for example, mixed with other amino acids resulting from the in carcass rendering, with the aid of an enzyme or of an enzyme mixture, e.g. D- amino acid oxidase or in combination with L-amino acid oxidase and catalase, to the corresponding 1,2-dehydro compound, and the 1,2-dehydro compound obtained in this way is reduced with sodium borohydride (NaBH4). In order to be able to reuse the enzymes, they are introduced in immobilized form into the reaction medium. For example, the enzyme or enzymes are introduced into the reaction medium in a dialysis tube or immobilized on synthetic resin beads.
Patent AT-392855-B (AT)
Title: Torsion spring suspension and method for producing it
Inventor: HILLSTROM DAVID UNO
IPC: G09F7/22
Filed: 1987-11-12
Granted: 1991-06-25
Abstract: A description is given of a torsion spring suspension 878 having at least one torsion spring for connecting a holder 871, 872 for, e.g., boards (tickets, plates, labels, stickers, tags) or similar information or advertising media to a frame 886, where the holder 871, 872 can be pivoted (swivelled) resiliently relative to the frame 886 from its rest position about the torsion spring axis. The torsion spring is formed by at least one elastomeric member 879 provided between two sleeves 876, 880. Said member is biased, or can be biased, during assembly, for example by compression and/or rotation relative to the torsion spring axis. <IMAGE>
Patent AT-388549-B (AT)
Title: Process for forming a refractory composition on a surface and formulations for forming such a refractory composition on a surface
Inventor: ROBYN PIERRE
IPC: C04B35/65
Filed: 1985-12-02
Granted: 1989-07-25
Abstract: The invention relates to a process for forming a refractory composition on a surface, in which a mixture of refractory particles and oxidizable materials which react exothermically with oxygen and generate sufficient heat to soften or melt at least the surfaces of the refractory particles and thus lead to formation of this refractory composition is sprayed against this surface. The particular feature of the invention is that the particle size of the particles which are sprayed in the mixture is such that the mean of the 80% and 20% particle sizes of the refractory particles is greater than the mean of the 80 and 20% particle sizes of the oxidizable particles and that the particle size range distribution factor of the refractory particles is at least 1.2. This factor f(G) is 2 (G80 - G20 : G80 + G20) = 1.2, with G80 being the 80% particle size of the particles of this species and G20 being the 20% particle size of the particles of this species.
Patent DK-158677-B (DK)
Inventor: MARKUSSEN JAN
IPC: A61K/
Filed: 1986-03-10
Abstract: Insulin derivatives having a charge which is positive compared with the charge of human insulin at neutral pH, can be used to prepare solutions having prolonged insulin action. In the novel insulin derivatives, a basic amino acid has been substituted in the B27-position and/or a neutral amino acid has been inserted in the A4-, A17-, B13- and/or B21-position. Furthermore, the C-terminal carboxyl group of the B-chain has been blocked with an amido or ester residue.
Patent DK-161985-B (DK)
Inventor: AKESAKA TOSHIO
IPC: E21D9/06
Filed: 1984-04-13
Abstract: for thrusting a shield for use in tunneling includes the steps of causing a rotary head (14), provided at the front portion of a shield body (12), an eccentric motion sothat earth, soil or sand covering the front of the shield is pressed away radially of the shield, and exerting a thrust on the shield body during the eccentric motion of said rotary head. Apparatus for carrying outthe method includes a driven crank shaft (22) or a driven eccentric straight shaft, a conical or frustoconical rotary head (14) supported rotatably by the crank or eccentric straight shaft, conveyor for discharging mined material backwardly, and hydraulic jacks for imparting a thrust to the shield bodv.
Patent DK-154885-B (DK)
Inventor: SKYLLINGSTAD OLAV
IPC: B65G65/48
Filed: 1984-10-10
Abstract: The present invention relates to a transportable container (1) for transport and storage of solids. The container (1) is permanently mounted in a framework with means allowing lifting by crane and/or fork truck, and the upper part of the container (1) is cylindrical or polygonal and both the upper and the lower part of the container (1) has means for watertight closure. The lower part of the container (1) is closed by a bottom plate (2) fastened to the container (1) by a flange (3), and on the bottom plate (2) there is arranged a movable scraping device with spokes (4) fastened to a shaft (9) which can be connected to external driving means. In the plate (2) there is a discharge opening (8) which can be watertight closed by a movable flap (6) arranged under the plate (2). Inside the container (1) a screen (15) can be arranged covering the discharge opening (8). The flap (6) is fastened and can be moved around a pin (10) in the plate (2) such that the area of the effective discharge opening (8) can be varied, or the flap (6) can be arranged in guiding means (7) and can be moved back and forward in these.
Patent FI-75154-B (FI)
Inventor: DAVE KRISHNA G
IPC: C07D211/16
Filed: 1980-05-26
Granted: 1988-01-29
Abstract: The invention relates to novel guanidine derivatives, particularly to substituted guanidines of the formula    <IMAGE>  (I)  having hypoglycaemic activity, for the oral treatment of hyperglycaemia in mammals, especially for the oral treatment of Diabetes mellitus.
Patent FI-61739-B (FI)
Inventor: LAMPINEN MARKKU
IPC: F26B13/24
Filed: 1980-07-01
Granted: 1982-05-31
Abstract: Objects constituted by a porous web-like material, such as a paper web, a granular material, such as peat, or a solid material such as wood, are dried by placing the same in contiguity with a fine porous liquid suction surface which itself is in liquid communication with a liquid volume with the latter being in communication with apparatus by which the liquid in the liquid volume is maintained at an underpressure relative to the pressure of the liquid in the object to be dried so that liquid flows from the object into the fine porous suction surface. The liquid flow can be enhanced through the application of an over pressure or through the direction of radiation onto the object to be dried. In one embodiment, the fine porous liquid suction surface comprises the surface of a rotatably mounted cylinder whereby a web-like object, such as a paper web, can be dried as the same is carried on the cylinder surface.
Patent FI-72994-B (FI)
Inventor: BARLOW PETER LEWIS
IPC: E01C5/22
Filed: 1982-06-28
Granted: 1987-04-30
Abstract: A preformed membrane, suitable for road surfacing, comprising a layer of a mixture of bitumen, a linear styrene/conjugated diene block copolymer and a branched styrene/conjugated diene block copolymer.
Patent FI-81199-B (FI)
Inventor: LADRIERE SERGE
IPC: F42B/
Filed: 1984-07-16
Granted: 1990-05-31
Abstract: PCT No. PCT/FR83/00228 Sec. 371 Date Jul. 18, 1984 Sec. 102(e) Date Jul. 18, 1984 PCT Filed Nov. 24, 1983 PCT Pub. No. WO84/02183 PCT Pub. Date Jun. 7, 1984.The projectile comprises a central core, a rear body of which the diameter determines the gauge of the projectile, and an interlock for the central core with the rear body. This interlock comprises a conical sleeve coupling formed by a conical recess and a conical finger, having complementary shapes arranged to provide a self-clamping effect. The rear body comprises at least one bulge cooperating with the gun barrel of the armament and at least one hollow. The bulge and hollow being interconnected progressively so as to define a continuous sinuous shape.
Patent FI-81132-B (FI)
Inventor: LINDAHL JONAS ARNE INGVAR
IPC: D21B1/14
Filed: 1985-09-09
Granted: 1990-05-31
Abstract: An improved high yield pulp, such as groundwood pulp, thermomechanical pulp, chemimechanical pulp and waste paper pulp having a widened field of use is produced by treating the raw material in a known manner, screening, thickening and bleaching, the pulp subsequent to being bleached at a low pulp consistency being mechanically worked and divided in a fractionating apparatus into a long-fibre fraction and a fine-fibre fraction. The freeness of the long-fibre fraction exceeds and freeness of the fine-fibre fraction by 150-600 ml C.S.F. and the fine-fibre fraction constituents 35-70 % by weight of the pulp quantity obtained after the bleaching stage.