Patent SG-11201810368P-A (SG)
Title: Accurate dose control mechanisms and drug delivery syringes
Inventor: CASTAGNA LOU
IPC: A61M5/315
Filed: 2016-05-24
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 111111H111011111111111111111111111111011010H0111111111111101111111111011110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date . . .., . .. WO 2017/204787 Al 30 November 2017 (30.11.2017) WIPO I PCT (51) International Patent Classification: (74) Agent: CARROLL, Alice O.; Hamilton, Brook, Smith & A61M 5/315 (2006.01) Reynolds, P.C., 530 Virginia Road, P.O. Box 9133, Con- (21) International Application Number: cord, Massachusetts 01742-9133 (US). PCT/US2016/033950 (81) Designated States (unless otherwise indicated, for every (22) International Filing Date: kind of national protection available): AE, AG, AL, AM, 24 May 2016 (24.05.2016) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, (25) Filing Language: English EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, (26) Publication Language: English HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, (71) Applicant: UNITRACT SYRINGE PTY LTD [AU/AU]; MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, Suite 3, Level 11, Chifley Square, Sydney, New South PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, Wales 2000 (AU). SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (72) Inventor; and (71) Applicant: YOUNG, Nathaniel Ryan [US/US]; 10251 (84) Designated States (unless otherwise indicated, for every Fenmore Road, Felton, Pennsylvania 17322 (US). kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (72) Inventors: CASTAGNA, Lou; 1901 Scarlett Lane, Mid- UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, dletown, Pennsylvania 17057 (US). RICHARDSON, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Gary; 3645 Raintree Road, York, Pennsylvania 17404 EE, ES, FL FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (US). SHETTY, Gautam N.; 1707 Marietta Ave., #3A, - MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, = Lancaster, Pennsylvania 17603 (US). TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (54) Title: ACCURATE DOSE CONTROL MECHANISMS AND DRUG DELIVERY SYRINGES = (57) : A dose control mechanism (510, 610) for a syringe includes an engaging screw thread 512A = arrangement between an exterior surface of a plunger (514, 614) and a longitudinally extending channel 7 (520D, 620D) of a housing (520, 620). The engaging screw thread arrangement includes at least one = = = = = = = = 510 = - = = - 11 IN GC 71' © N 1 IN 1-I 0 ei 530C. 520E- 520E-, 5188 51' 518E 1 518A 534A1 7 7 5368 1 I thread segment (514B, 614B) and a pitch guide (520C, 620C) including a variable pitch thread. At least 517 a portion of the longitudinally extending channel (520D, 620D) of the housing (520, 620) including one -14 514C of the pitch guide ( 520C, 620C) and the at least one thread segment (514B, 614B), and the plunger (514, 614) includes the other of the pitch guide (520C, 620C) and the at least one thread segment (514B, 5 1 6 614B). The plunger (514, 614) resides at least partially within the housing (520, 620) with the at least one -520 thread segment (514B, 614B) engaged with the pitch guide (520C, 620C). An accurate dose drug delivery , 514 30 syringe (500, 600) includes such a dose control mechanism (510, 610), a barrel (540, 640), a plunger seal 520C (536, 636), and a barrel adapter assembly (450) having a barrel tip (452) and a needle (454). The syringe voo (500, 600) may be a fill-at-time-of-use syringe, a pre-filled syringe, or a safety syringe having integrated \"'ROA 518 needle retraction or needle sheathing safety features, or a combination thereof. Methods of assembly, manufacturing, and operation are similarly disclosed. 518D - 110 30A 1 - 5 40 A FIG. 8A O [Continued on next page] WO 2017/204787 Al MIDEDIMOMMIDIRMEM00101011MMEOHINVOIMIE Published: — with international search report (Art. 21(3))