baber/WOPTO huggingface dataset:
Patent PT-817615-E (PT)
Inventor: MARTTILA ESKO
IPC: A61K47/30
Filed: 1996-03-20
Abstract: PCT No. PCT/FI96/00164 Sec. 371 Date Dec. 2, 1997 Sec. 102(e) Date Dec. 2, 1997 PCT Filed Mar. 20, 1996 PCT Pub. No. WO96/29058 PCT Pub. Date Sep. 26, 1996The invention relates to a peroral composition providing controlled release of a drug, the composition comprising a) a core comprising the drug and a drug release controlling agent and b) an enteric coating comprising the drug release controlling agent, wherein the drug release controlling agent consists substantially of a pH-sensitive enteric polymer. Preferably the pH-sensitive enteric polymer has a pH dissolving point of at least 6.5. The composition is preferably in the form of granules. Preferably, the composition is in the form of enteric matrix granules coated with an enteric coating. The composition releases the drug gradually in the lower gastrointestinal tract. The composition is especially suitable for the administration of 3-(3-cyanophenyl)methylene-2,4-pentanedione into the colon.
Patent PT-831899-E (PT)
Title: Recombinant poxvirus-calicivirus compositions and uses
Inventor: PAOLETTI ENZO
IPC: C07K14/15
Filed: 1996-06-03
Abstract: Attenuated recombinant viruses containing DNA encoding a calicivirus antigen such as a RHDV antigen, e.g., a capsid gene, as well as methods and compositions employing the viruses, expression products therefrom, and antibodies generated from the viruses or expression products, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The recombinant viruses and gene products therefrom and antibodies generated by the viruses and gene products have several preventive, therapeutic and diagnostic uses. The DNA from the viruses can be used for probes or for primers.
Patent PT-911375-E (PT)
Inventor: YAMASHITA KENJI
IPC: C08L33/10
Filed: 1997-10-20
Abstract: The aqueous dispersion of a peelable coating composition of the present invention is (a) a mixture containing 5-40% by weight of an emulsion of an acrylic copolymer having a glass transition temperature (hereinafter referred to as "Tg") of not lower than 40 DEG C, and 95-60% by weight of an emulsion of another acrylic copolymer having a Tg ranging from -20  DEG C through 5 DEG C. The acrylic copolymer emulsion mixture (b) contains ethylenically unsaturated vinyl monomers having acid value in a total amount of 0.5-1.0% by weight, and (c) at least one of the acrylic copolymer emulsions is an acrylic copolymer which has been polymerized by use of a reactive surfactant, and (d) the particle size of the acrylic copolymer emulsions is not more than 200 nm.
Patent PT-798309-E (PT)
Inventor: FUJIBAYASHI YASUHISA
IPC: C07H13/04
Filed: 1997-03-27
Abstract: A diagnostic agent for glycometabolic function comprising a glucose derivative of the formula (I): <CHEM> wherein R<1>, R<2>, R<3> and R<4> are the same or different and each represents hydrogen or acyl having 2 to 8 carbon atoms, with the proviso that at least one of R<1>, R<2>, R<3> and R<4> is acyl and R<5> represents X or -NHCOR<6>X wherein X is a radioisotope of halogen and R<6> is arylene or alkylene having 1 to 3 carbon atoms.
Patent PT-898466-E (PT)
Inventor: BARNEY WARD W
IPC: B31B50/64
Filed: 1997-04-11
Abstract: A method for forming a flexible container (10) for combined storage and administration is described. The method comprising the steps of sealing flexible front and rear sheets (12, 14) together at a common peripheral edge (16); heating the front and rear sheets (12, 14) in a first localised area to form a first peelable seal (24) extending between two sides of the common peripheral edge (16), the first peelable seal (24) separably joining the front and rear sheets (12, 14) to thereby form a first compartment (18) for containing a first product; and heating the front and rear sheets (12, 14) in a second localised area to form a second peelable seal (26) extending between the two sides of the common peripheral edge (16), the second peelable seal separably joining the front and rear sheets (12, 14) to thereby form an outlet compartment (22) and a second compartment (20) for containing a second product, the second compartment (20) being between the outlet compartment (22) and the first compartment (18). For ease of manufacture and filling first and second sacrificial ports (102, 104) are provided which are interposed between the front and rear sheets (12, 14) and are in communication with the first and second compartments (18, 20), respectively; with the first compartment (18) is filled with a first product through a respective sacrificial port (102); the second compartment (20) is filled with a second product through a respective sacrificial port (104); and the seal along the common peripheral edge (16) is completed and the sacrificial ports (102, 104) are removed from the container (10).
Patent PT-929563-E (PT)
Inventor: OR YAT SUN
IPC: A61K31/70
Filed: 1997-09-02
Abstract: 6-Substituted ketolides of e.g. formula (II) or (III), and their salts, esters and prodrugs are new: Y + Z = X; X = OH, =NOR1 or =NOC(R5)(R6)OR1; or one of Y and Z = H; and the other = H, OH, protected OH or NR7R8; R1 = 1-12C alkyl (optionally substituted), 3-12C cycloalkyl or SiR2R3R4; R2-R4 = 1-12C alkyl or aryl; R5, R6 = H or 1-12C alkyl (optionally substituted), or R5 + R6 = 3-12C cycloalkyl; R7, R8 = H or 1-6C alkyl; or NR7R8 = 3-7 membered ring which, when the ring is 5-7 membered may optionally contain O, NH, N(1-6C alkyl), N(aryl), N(aryl-1-6C alkyl), N (substituted aryl-1-6C alkyl), N(heteroaryl), N(heteroaryl-1-6C alkyl), N(substituted heteroaryl-1-6C alkyl), S or S(O)n; n = 1 or 2; Ra = H or OH; Rc = H or hydroxy protecting group; R9 = 1-6C alkyl (optionally substituted), 3-7C cycloalkyl or optionally substituted aryl or heteroaryl; M = CONH, NHCO, NH, N=, NMe, NHCOO, NHCONH, OCONHY, OCOO, O, S(O)n, COO, OCO or CO; R = methyl (substituted by CN, F, CO2R10, S(O)nR10, NHCOR10, NHCONR11R12, aryl, substituted aryl, heteroaryl or substituted heteroaryl); 2-10C alkyl (optionally substituted), 3C alkenyl (substituted by halo, CHO, CO2R10, COR9, CONR11R12, CN, optionally substituted aryl or heteroaryl, 3-7C cycloalkyl or 1-12C alkyl substituted by heteroaryl); 4-10C alkenyl (optionally substituted), or 3-10C alkynyl optionally substituted); R10 = 1-3C alkyl (optionally aryl substituted), or heteroaryl substituted 1-3C alkyl; R11, R12 = H or 1-3C alkyl (optionally substituted); A, B, D, E = H, 1-6C alkyl (optionally substituted by optionally substituted), 3-7C cycloalkyl, optionally substituted aryl or heteroaryl, heterocycloalkyl or 1-6C alkyl substituted by MR9; provided that \- 2 of A, B, D and E = H; or any one pair of substituents, consisting of AB, AD, AE, BD, BE or DE taken with the atoms to which they are attached, form a 3- to 7-membered ring optionally containing O, NH, N(1-6C alkyl), N(aryl-1-6C alkyl), N(substituted aryl-1-6C alkyl), N(heteroaryl-1-6C alkyl), N(substituted heteroaryl-1-6C alkyl), S, S(O)n, CONH, CONR12, NHCO, NR12CO or C(=NH)NH.
Patent PT-880868-E (PT)
Inventor: KURTZ SCOTT DAVID
IPC: H04B1/66
Filed: 1997-11-04
Abstract: A wireless communication unit comprising means for transmitting data to a second communication unit using at least one of a plurality of data rates, at least one of a plurality of time slots, at least one of a plurality of modulation schemes, and at least one of a plurality of coding rates in a plurality of time division multiple access (TDMA) frames.
Patent PT-859020-E (PT)
Inventor: SCHMIDT WOLFGANG DR
IPC: C08G63/183
Filed: 1998-02-02
Abstract: The present invention provides a method of synthesizing polypropylene terephthalate with no more than 5 ppm acrolein and no more than 3 ppm allyl alcohol. The method comprises direct esterification of terephthalic acid with 1,3-propanediol in the presence of 30 to 200 ppm titanium in the form of an inorganic esterification catalyst containing at least 50 mol % TiO2 precipitate, blocking the esterification catalyst after esterification by adding 10 to 100 ppm phosphorus in the form of a phosphorus-oxygen compound, and then performing precondensation and polycondensation in the presence of 100 to 300 ppm antimony in the form of a conventional antimony polycondensation catalyst and optional conventional coloring agent.
Patent PT-908558-E (PT)
Inventor: PITKANEN MAIJA
IPC: D21H11/10
Filed: 1998-09-16
Abstract: The present invention concerns a method for producing a base paper for fine papers, the base paper being produced from a mixture of a mechanical pulp and a chemical pulp. The chemical pulp used comprises a chemical softwood pulp having a elastic modulus close to that of the mechanical pulp and a great bonding strength. It is preferred to use a chemical softwood pulp which produces a sheet having a elastic modulus of less than 6000 N/mm<2> when the bonding strength is 400 J/m<2>. A pulp of this kind has a good ScottBond strength at the same light scattering. The base paper produced by the method can therefore be used in double-coated fine papers which require a large bonding strength of the base paper.
Patent PT-973463-E (PT)
Inventor: PADILLA JAMES D JR
IPC: A61M5/158
Filed: 1998-03-23
Abstract: An intravenous site protection device is formed with a rigid, elongated top member and a rigid, elongated bottom member which are oppositely secured on a patient's extremities. The top member is configured to accommodate a catheter and supply tubing to prevent accidental dislodgement during transportation or movement of the patient. Securing straps maintain the top and bottom members against the extremity of the wearer and a resilient sponge is positioned beneath the top member, against the wearer's skin, to assure proper circulation to the intravenous site. The rigid plastic ensures protection of the intravenous site should the site be struck or contacted with clothing or other articles during intravenous fluid transfer. The preferred form of the invention is made from a transparent plastic to allow ease in monitoring by medical personnel.
Patent PT-1037871-E (PT)
Inventor: BERZSENYI PAL
IPC: C07C233/36
Filed: 1998-12-10
Abstract: The present invention relates to novel, antiarrhythmically active phenoxyalkylamine derivatives possessing a double point of attack. More particularly, the present invention relates to new phenoxyalkylamine derivatives of the formula (1)whereinR1 and R2, independently from each other, mean hydrogen, halogen or C1-4 alkyl group;R3, R4 and R5, independently from each other, stand for hydrogen or C1-4 alkyl group;R6 represents hydrogen, C1-4 alkyl or benzyl group;R7 means nitro group or amino group optionally monosubstituted by C1-4 alkyl, benzoyl, C1-4 alkylcarbonyl, C1-4 alkylsulfonyl, C1-4 alkylcarbamoyl or C1-4 alkylthiocarbamoyl group;both n and m are 0 or 1,with the proviso that R2 is different from hydrogen, when R1 is hydrogen,as well as stereoisomers or mixtures of stereoisomers thereof, acid addition salts thereof and hydrates, prodrugs and metabolites of all these compounds.
Patent PT-1056357-E (PT)
Inventor: MARK DAVID A
IPC: A23L1/304
Filed: 1998-12-30
Abstract: An enteral composition and method for providing nutrition to metabolically stressed patients. The enteral composition has an energy density of about 1.4 to 1.8 kcal/ml. The enteral composition includes a protein source providing 15% to 20% of the energy of the composition, a lipid source, and a carbohydrate source. The enteral composition has a ratio of non-protein calories per gram of nitrogen of at least about 90:1.
Patent PT-945728-E (PT)
Inventor: SCATIZZI MARIO
IPC: D06B23/10
Filed: 1999-03-19
Abstract: Apparatus for the controlled withdrawal and delivery of volumetrically metered liquids of a type comprising a support structure able to receive a first series of vessels or bottles which contain substances in a liquid phase, and a second series of vessels or glasses able to receive one or more said substances in preset doses, means being provided for withdrawing and feeding said substances in preset doses and able to withdraw said substances individually from said bottles and discharge them into said glasses, apparatus characterized in that said withdrawal and delivery means comprise a series of single withdrawal and delivery members (7) able to be positioned in correspondence of each of said bottles and resolvably matchable with an actuation and driving head (6) . <IMAGE>
Patent PT-1100562-E (PT)
Inventor: BOTICH MICHAEL
IPC: A61M25/08
Filed: 1999-05-13
Abstract: A catheter insertion device (10) is provided for inserting an over-the-needle catheter (70). The device (10) includes an insertion needle (30) that is retractable into the housing (20) of the device (10) after use to prevent exposure to the contaminated needle (30). The needle retainer (40) releasably retains the needle (30) in an extended position against the rearward bias of the biasing element (60). The needle retainer (40) engages the hub (72) of the catheter (70) so that when the catheter is removed from the insertion device (10), the needle retainer (40) automatically releases the needle (30). The biasing element (60) then propels the needle rearwards into the housing (20) of the device. Further, a device for inserting a guide wire into a patient is also provided along with methods of inserting the guide wire.
Patent PT-1100922-E (PT)
Title: Uses of the borreliacidal epitope(s) of borrelia burgdorferi outer surface protein c (ospc) as vaccine
Inventor: SCHELL RONALD F
IPC: A61K39/00
Filed: 1999-07-30
Abstract: An OspC Dra fragment fusion peptide isolated from Borrelia burgdorferi is described herein for the prevention, treatment and early diagnosis of Lyme disease in humans and other animals. This invention also relates to a screening method detecting anti-Osp borreliacidal antibody activity, and antibodies reacting with a protein fragment encoded by a DraI-SmaI DNA fragment of OspC.
Patent PT-1140413-E (PT)
Inventor: CULLEN BARRY JAMES
IPC: B23K26/00
Filed: 1999-12-21
Abstract: The invention provides the use of a slab laser beam for the cutting of an ultra-hard material such as PCD or PCBN.
Patent SG-59588-G (SG)
Title: Poly(arylene sulfide)printed circuit boards
IPC: H05K1/03
Filed: 1988-09-14
Abstract: A printed circuit board is made of a poly(arylene sulfide) board and a conductive metal deposited on the board by electroless plating. Adhesion between the poly(arylene suifide) and the conductive metal is improved by allowing the plated poly(arylene sulfide) to age.
Patent SG-103887-G (SG)
Title: Tetrahydronaphthalene and indan compounds, their production and pharmaceutical preparations
IPC: A61K31/10
Filed: 1987-11-25
Abstract: This invention is directed to tetrahydronaphthalene and indane compounds and processes thereto. These compounds are useful as tumor inhibiting agents, in the treatment of neoplasms and dermatological conditions.
Patent IE-35555-L (IE)
Title: Removal of iron from titaniferous ores
IPC: C22B34/12
Filed: 1971-03-12
Abstract: Process for beneficiating titaniferous ores to produce essentially pure titanium dioxide comprising alternatingly contacting the ore in a gas-solids reactor with carbon monoxide for a short period of time and then with chlorine for a short period of time and then repeating the alternate carbonylation and chlorination steps at temperatures of 700 to 1,150 DEG C. under fluidizing conditions; converting iron oxide and oxides of metals other than titanium in the ore to iron and other metal chlorides and removing same by volatilization. The titanium dioxide produced is useful as a starting material for the preparation of titanium dioxide pigment.
[US3699206A]
Patent IE-880342-L (IE)
Title: Golf club cleaning apparatus
IPC: A63B57/00
Filed: 1988-02-08
Abstract: A golf club cleaning apparatus comprises a housing 11 having means for supporting a plurality of golf clubs 13 in a common orientation with their heads spaced apart in a cleaning compartment, and means for directing a fluid onto the heads of the clubs in the cleaning compartment. In particular, the support means comprises an upright shaft 14 rotatable about its own axis and two holding plates 15 and 16 fixed to the shaft at axially spaced locations, each holding plate having a set of apertures 17 surrounding the shaft, the sets of apertures being aligned to receive the shaft portions of golf clubs, and the cleaning compartment being located below the lower holding plate 16. <IMAGE>
[GB2215619A]
Patent IE-31867-L (IE)
Title: Fried potato product
IPC: A23L19/12
Filed: 1968-04-08
Abstract: 1,183,789. Expanded potato products; potato flour. NIBBIT PRODUCTS ASSOCIATION Ltd. 10 April, 1968 [26 April, 1967], No. 17414/68. Headings A2B and A2Q. A crispy expanded fried foodstuff is prepared by grinding raw potatoes, which may have been peeled, for example by lye, to form a liquid slurry, a bleaching agent, for example sodium bisulphite, being added during or after the grinding, adding 0-70 parts by weight of a starch, for example cornstarch tapioca, or preferably raw potato starch, to 100 parts by weight of the slurry, to form a liquid mass having a solids content of 18-50 per cent, drying, for example on a drum dryer or a scraped surface heat exchanger, to obtain a powder with a moisture content of less than 10 per cent, grinding to form a flour, adjusting the reducing sugar content to 1-2 wt. per cent mixing with water and salt to a moisture content of 28-35 per cent, extruding under pressure to give coherent bands which are cut into pieces, dried to a moisture content of 6-10 per cent, and fried in hot fat. Prior to extrusion, the swelling power of the mass may be adjusted by the addition of an instant potato product. Other starches, such as cornstarch or tapioca, may be used.
[GB1183789A]
Patent FI-823239-L (FI)
Inventor: HEGI PAUL
IPC: H04M1/274
Filed: 1982-09-21
Abstract: An automatic dialer for telephone numbers comprises a control unit (100), a memory unit (200), a keyboard unit (300), a display unit (400), units for voltage feed (550) and regulation (500), units for amplification (600) and automatic regulation of signal level (700), a signal shaping unit (900) and a unit for connection with a telephone line (800). At least the memory unit (200) is housed in a removable portion that plugs into a fixed portion containing the other units. This memory unit contains identification information corresponding to a local telephone network; and a memory of the control unit contains identification information corresponding to the local telephone network to which this fixed portion is connected. The control unit comprises a comparator comparing the identification information of a fixed portion and of the removal portion which plugs into this fixed portion, and controls modifications of the operating program of the control unit as a function of the result of this comparison.
Patent IE-42690-L (IE)
Title: Oil-absorbing material
IPC: E02B15/10
Filed: 1976-05-13
Abstract: 1513645 Material for absorbing oil on water MITSUI TOATSU CHEMICALS Inc 13 May 1976 [22 May 1975] 19649/76 Heading C1C [Also in Division Dl] An oil-absorbing material is prepared by mixing vegetable fibres i.e. grass peat, flax, coconut shell, straw or grass fibres with up to 35% by weight, based on the dry fibre, of an olefin polymer and then heating the mixture to impregnate the fibres with the molten polymer. Specified olefin polymers are homopolymers or copolymers of ethylene, propylene, isobutylene or butene and copolymers of ethylene with vinyl acetate, acrylic acid or salts or esters thereof and methacrylic acid or salts or esters thereof. The materials are used for treating oil-on-water pollution.
[GB1513645A]
Patent IE-801061-L (IE)
Title: 3-thiovinyl-cephalosporins.
IPC: C07D/
Filed: 1980-05-21
Abstract: Novel cephalosporins of the general formula (I); <IMAGE> (I) in which R is alkyl, L-2-amino-2-carboxy-ethyl, phenyl, pyridyl, pyridyl-N-oxide, pyrimidin-2-yl, substituted pyridazin-3-yl, 5,6-dioxo-1,4,5,6-tetrahydro-1,2,4-triazin-3-yl substituted in the 4-position, 1,3,4-triazol-5-yl or 2-alkoxycarbonyl-1,3,4-triazol-5-yl substituted in the 1-position, 1,4-dialkyl-5,6-dioxo-1,4,5,6-tetrahydro-1,2,4-triazin-3-yl, 1-alkyl-5,6-dioxo-1,4,5,6-tetrahydro-1,2,4-triazin-3-yl, 2-alkyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl, triazol-5-yl, 1,3,4-thiadiazol-5-yl which is substituted or unsubstituted, 1,2,4-thiadiazol-5-yl which is substituted, 1,3,4-oxadiazol-5-yl which is substituted or unsubstituted, oxazol-2-yl which is substituted or unsubstituted or tetrazol-5-yl which is substituted or unsubstituted in the 1-position, R' is a hydrogen atom or a radical of the general formula (II); <IMAGE> (II) and Ro is hydrogen, alkyl, vinyl or cyanomethyl, as well as their salts, are useful as anti-bacterial agents.
[US4307116A]
Patent IE-41380-L (IE)
Title: Information transmission system
IPC: G08B25/00
Filed: 1975-06-12
Abstract: 1476261 Alarm systems ABOYNE PTY Ltd 16 June 1975 [18 June 1974] 25631/75 Headings G4H and G4N An information transmission system comprises: (a) a transmitter arranged to transmit in two modes viz. a monitoring mode wherein monitoring signals of duration #t spaced apart by time t (greater than #t) are employed to modulate a carrier, and an alarm mode in which the carrier is modulated by alarm signals having a greater repetition rate than the monitoring signals, (b) a receiver which detects a change in the mode, and also if no signal with the duration 8t is detected within each period of successive predetermined (fault detecting) periods of time xt (greater than t). As disclosed, the monitoring and alarm signals are identical, each being a 600-microsecond multi-bit message in diphase form frequency-modulated on to the (RF) carrier, the monitoring mode involving repeating this message once per minute indefinitely and the alarm mode involving repeating it once per 800 microseconds (i.e. with 200 microsecond gaps) twenty times. A multi-storey building has a number of transmitters and a receiver, on each floor, communicating by radio, the receivers being coupled by cable to a control unit (with display) for the building which is connected by transmission line to a fire control authority station. A transmitter switches from monitoring mode to alarm mode on detecting fire (temperature or smoke). The message specifies the building, floor and sensor identities and includes a parity bit and extra bits. At a receiver, the received message is demodulated with signal duration and interval checks and fed to a shift register with a parity check. The message is rejected if it does not contain the correct building and floor identities and extra bits, and have correct parity. For monitoring, the sensor identity is decoded to set a respective sensor presence flip-flop. Every ten minutes these flip-flops are reset, and those which were not set in the previous ten minutes set respective sensor fault flip-flops to light respective fault lamps. The transmitters are battery-driven; fault may be flat battery. In the alarm mode, the sensor identity is compared with that in the previous message, equality setting a fire flip-flop respective to the sensor identity (as decoded), each fire flip-flop controlling a respective fire lamp (the two messages compared must occur within a predetermined period less than t). Ranges of values for the various intervals and durations are given, those above being merely preferred. Application to security and pollution level detection is mentioned.
[GB1476261A]
Patent IE-35823-L (IE)
Title: Dentifrice composition
IPC: A61Q11/00
Filed: 1971-11-19
Abstract: 1302019 Dentifrice composition COLGATEPALMOLIVE CO 3 Nov 1971 [27 Nov 1970] 56579/70 Heading A5B A dentifrice comprises (a) 1,6-di (p-chlorophenylbiguanido) hexane (chlorohexidene) and (b) alpha-alumina trihydrate of particle size 2.5-11.5 microns as polishing agent. The composition may also contain glycerol, hydroxyethyl cellulose, sodium N-lauroyl sarcosinate, sodium saccharin, water, colouring and flavouring.
[GB1302019A]