baber/WOPTO huggingface dataset:
Patent DE-69033179-T3 (DE)
Inventor: DALE JAMES
IPC: C12Q1/6813
Filed: 1990-02-13
Granted: 2005-01-27
Abstract: A method for detecting a specific polynucleotide sequence in a material is disclosed. The method includes exposing said material to an oligonucleotide primer having a sequence complementary to part of said specific polynucleotide sequence wherein said primer binds to part of said polynucleotide sequence when present in said material. Primer bound to the polynucleotide sequence is extended wherein any extended primer includes a detectable element and/or a separation element. Any extended primer is then separated into a fraction wherein said fraction does not have detectable element not included in said extended primer. One then determines whether any extended primer is present in said fraction by assaying said fraction for said extended primer wherein the presence of said extended primer is indicative of the presence of the specific polynucleotide sequence in said material and the absence of said extended primer in said fraction is indicative of the absence of the specific polynucleotide sequence in said material.
Patent DE-69110710-T3 (DE)
Inventor: HAUCK JOHN A
IPC: A61N1/365
Filed: 1991-01-23
Granted: 2000-08-31
Abstract: A rate adaptive cardiac pacemaker incorporating a switched capacitor filter whose cut-off frequency is varied as a function of heart rate allows respiration-related signals appearing in the intracardiac impedance waveform to be separated from signals relating to systolic events over a frequency range of interest, allowing either or both of the respiration-related signal component or the systolic event component to be used in adjusting the pacing rate. <IMAGE>
Patent DE-69124387-T3 (DE)
IPC: A61K38/00
Filed: 1991-09-16
Granted: 2011-02-17
Abstract: An altered antibody chain is produced in which the CDR's of the variable domain of the chain are derived from a first mammalian species. The framework-encoding regions of DNA encoding the variable domain of the first species are mutated so that the mutated framework-encoding regions encode a framework derived from a second different mammalian species. The or each constant domain of the antibody chain, if present, are also derived from the second mammalian species.
Patent DE-69517149-T3 (DE)
Inventor: SCHMITZ CHRISTOPH JOHANN
IPC: A61F5/44
Filed: 1995-02-16
Granted: 2006-12-14
Abstract: In an absorbent article, a mechanical fastening system is provided wherein the landing member (64) comprises a loop-type material. The landing member is elastically extensible in the direction of the front transverse edge by at least 5 %, preferably at least 30 %, so that it allows for elastic contraction and expansion of the front waist region. The landing member (64) may be of extensible material and may be formed by the topsheet material which projects beyond the front transverse edge of the backsheet, or topsheet material which is doubled over at the front waist region. Alternatively, the backsheet comprises a front waist section of different material than the back waist section. A separate elastic element may be associated with the landing member, or the landing member itself may be of stretchable loop-type material. In another embodiment, the landing member comprises at least one cut-out section (90) in the backsheet through with the loop-type material of the landing member is exposed.
Patent DE-69530261-T3 (DE)
Inventor: TONKS NICHOLAS K
IPC: C12N15/09
Filed: 1995-05-03
Granted: 2008-07-03
Abstract: Novel Type III density enhanced protein tyrosine phosphatases are disclosed and exemplified by human DEP-1 enzyme. Polynucleotides encoding huDEP-1 are disclosed, along with methods and materials for production of the same by recombinant procedures. Binding molecules specific for DEP-1 are also disclosed as useful for modulating the biological activities of DEP-1. <IMAGE>
Patent DK-1054130-T3 (DK)
Inventor: GROTEFELD HANS DIETER
IPC: B29C65/56
Filed: 2000-03-17
Granted: 2004-09-27
Abstract: The corner connector is in a miter-cut door or window hollow profile and involves a shaft (10), a frame with side walls and a base. A U-shaped cross-section guide (20) is inserted in the frame. The inclined surface of the shaft is formed by the base surface (22) of the U-shaped guide in the interior of the hollow profile. The tool for preparing the connector has a head on which is fixed a lever arm. On the head is an engagement member, particularly a hook, for securing a traction member of a clamping wedge.
Patent DK-1242405-T3 (DK)
Inventor: HEINER THOMAS
IPC: C07D401/06
Filed: 2000-12-20
Granted: 2004-11-01
Abstract: A process for the production of 4-(heteroaryl-methyl)-halogen-1(2H)-phthalazinones, especially 4-(4-pyridylmethyl)-1(2H)-phthalazinone, is described, which is characterized by the reaction of phthalidyl-3-triphenylphosphonium salt with 4-pyridine aldehyde in the presence of a basic adjuvant, subsequent reaction with hydrazine hydrate and subsequent acid treatment, whereby this process avoids the technical safety and environmental problems of the known processes.
Patent DK-1221432-T3 (DK)
Inventor: BACHER JUERGEN
IPC: F16J15/10
Filed: 2001-11-29
Granted: 2008-06-16
Abstract: Bodies made of expanded graphite are impregnated with low-viscosity, solvent-free, storage-stable, polymerizing acrylic resins up to resin contents of 50% by weight. A primary product made of expanded graphite has an open pore system, with a particularly preferred range of bulk densities of from 0.5 to 1.3 g/cm3 and with an ash value of not more than 4% by weight. Such bodies can also contain a proportion of additives. The impregnated, shaped and rapidly curable graphite bodies are employed as sealing elements, as components in fuel cells or as heat-conducting elements. A process for producing the bodies is also provided.
Patent DK-1358001-T3 (DK)
Inventor: LARSEN KNUD VERNER
IPC: B01D63/10
Filed: 2001-12-19
Granted: 2005-01-24
Abstract: A sanitary filtration plant including an oblong, tubular pressure vessel having one or more helical filter elements. Each helical filter element has a spiral-wound filter member and a central tube and, at an outlet end, a supporting structure formed as a wheel with a hub, spokes and a rim. The plane side of the downstream face of each supporting structure is provided with a plurality of recesses that are positioned between an opening between the spokes and the external periphery of the rim and extend circumferentially so as to be substantially concentric with said rim.
Patent DK-1274406-T3 (DK)
Inventor: BRAMBILLA GAETANO
IPC: A61L9/04
Filed: 2001-04-17
Granted: 2007-01-22
Abstract: A powder for use in a dry powder inhaler comprises: i) a fraction of fine particle size constituted by a mixture of physiologically acceptable excipient and an additive; ii) a fraction of coarse particles; and iii) at least one active ingredient. The powder is suitable for efficacious delivery of active ingredients into the low respiratory tract of patients suffering from pulmonary diseases such as asthma. In particular, the invention provides a formulation to be administered as dry powder for inhalation which is freely flowable, can be produced in a simple way, is physically and chemically stable and capable of delivering accurate doses and/or high fine particle fraction of low strength active ingredients by using a high- or medium resistance device.
Patent DK-1311707-T3 (DK)
Inventor: GANSHAW GRANT C
IPC: G06F17/00
Filed: 2001-08-17
Granted: 2009-02-16
Abstract: The present invention makes use of unique tags of a specific biopolymer that can be exploited for determining the concentration the biopolymer in crude solutions. In preferred embodiments the biopolymer is either a protein or a polynucleotide. Particularly, the invention provides a method for the determination and quantitation of biomolecules in crude mixtures by way of a separation technique in combination with mass spectroscopy. In one general embodiment, a target biomolecule is selected for analysis and an analog thereof is generated. Peak area integration of the peptide pairs provides a direct measure for the amount of target protein in the crude solution.
Patent DK-1383603-T3 (DK)
Inventor: DESMET GERT
IPC: C12Q1/68
Filed: 2002-04-11
Granted: 2007-01-02
Abstract: The present invention relates to a device for the simultaneous conduction of a multiplicity of binding reactions on a substrate with a first surface, said surface comprising discrete and isolated locations of one such binding reaction, said binding reaction being generated upon contact between the substrate and a fluidic sample comprising one or more target molecules capable of binding with at least one receptor molecule at least partly tethered to said first surface of the substrate, and further comprising means for enhancing the diffusion fluidic flow of the sample over the substrate, whereby said means for enhancing the diffusion fluidic flow comprises shear-force field generating means, whereby said means comprise a second surface positioned in a flow interacting manner in said flow channel, said second surface is able to be moved in a substantial parallel mode over the first surface.  The invention further relates to a method for binding one or more target molecules comprised within a fluid sample to at least one receptor molecule at least partly tethered to a first surface in a flow channel, wherein said target molecules are transported parallel to said first surface by means of shear-force field generating means, wherein the shear-force field generating means comprises a second surface, which second surface is moved in a substantially parallel mode past or over said first surface.
Patent DK-1406650-T3 (DK)
Inventor: EISENBACH-SCHWARTZ MICHAL
IPC: A61K35/14
Filed: 2002-06-27
Granted: 2009-03-02
Abstract: Methods and compositions are provided for preventing or inhibiting neuronal degeneration, or for promoting nerve regeneration, in the central nervous system (CNS) or peripheral nervous system (PNS), or for protecting CNS cells from glutamate toxicity, comprising an effective amount of an agent selected from the group consisting of (a) poly-Glu,Tyr and (b) T cells which have been activated by poly-Glue,Tyr.
Patent DK-1429807-T3 (DK)
Inventor: KLEIN THOMAS
IPC: A61K31/4409
Filed: 2002-09-17
Granted: 2007-06-18
Abstract: The invention relates to the combined use of a PDE4 inhibitor and a conventional NSAID in the treatment of an inflammatory disease and/or an inflammation-associated disorder while minimizing gastrointestinal side effects, such as gastric erosions and ulcer, which are frequently associated with the use of conventional NSAIDs. A preferred PDE 4 inhibitor for this combination is roflumilast or a derivative thereof. A preferred conventional NSAID for this combination is diclofenac or a derivative thereof.
Patent DK-1428175-T3 (DK)
Inventor: GEHR PETER
IPC: G06K7/10
Filed: 2002-09-06
Granted: 2005-12-12
Abstract: A label ( 1 ) made from a layer composite ( 15 ) includes at least one machine-readable diffractive bar code ( 3 ) consisting of narrow rectangular fields ( 4 ) occupied by the optically active structures and intermediate surfaces ( 5 ). The optically active structures which are covered by a reflection layer are embedded between layers of the layer composite ( 15 ). The diffractive relief structure used in the diffractive bar code ( 3 ) for the fields ( 4 ) diffracts and polarizes incident light and scatters the diffracted light into a half-space above the diffractive relief structure. A second diffractive relief structure differs at least in respect of the polarization of the polarizedly backscattered light with respect to the first diffractive relief structure. The second diffractive relief structure can be used for example for field surfaces of a second bar code in the bar code field ( 9 ) on the label ( 1 ) or for the intermediate surfaces ( 5 ). The light which is polarizedly backscattered at the diffractive bar code ( 3 ) can be detected by means of one of the known commercially available reading apparatuses for bar codes produced by printing. The bar code produced by printing can be used for individualizing the labels ( 1 ).
Patent DK-1446343-T3 (DK)
Inventor: VEIT FRANK W
IPC: B65G47/84
Filed: 2002-10-31
Granted: 2006-05-08
Abstract: A conveyor sorter includes a conveying surface movable in a longitudinal direction and a plurality of pusher shoes capable of traveling laterally of the conveying surface. At least one diverting rail is configured to selectively guide at least one of the pusher shoes laterally of the conveying surface. At least one diverter associated with the diverting rail is adapted to selectively transfer one or more pusher shoes to the diverting rail. The diverting rail has at least a first portion and a second portion. The first portion is at a first angle with respect to the longitudinal direction and the second portion is at a second angle with respect to the longitudinal direction that is different from the first angle. A pusher shoe guided by the diverting rail travels at a first lateral rate along the first portion and at a second, different lateral rate along the second portion. The first angle may be less than the second angle and a pusher shoe guided by the diverting rail traveling at the first lateral rate initially contacts an article on said conveying surface at the first portion. The second lateral rate would be higher than the first lateral rate for the duration of the diverting of the article. The diverting rail may be at least partially curved thereby providing a gradual junction between the first and second portions.
Patent DK-1448973-T3 (DK)
Inventor: BATESON IAN DAVID
IPC: G01N3/00
Filed: 2002-11-28
Granted: 2010-10-04
Abstract: A rheometer comprises a vessel mounted on a stand and a rotatable blade mounted above the vessel. A substance for rheometric assessment is put in the vessel. The rotor is advanced linearly into the substance while at the same time rotating. The blade is arranged with a profile such that there is substantially zero slip as it progresses, thereby minimising disturbance to the substance. The rheometric assessment is based on the axial force exerted as a result of the resistance of the substance to the progression of the blade through it.
Patent DK-1382284-T3 (DK)
Inventor: ARRIBAS CECILIO
IPC: A47K10/06
Filed: 2003-07-08
Granted: 2006-01-30
Abstract: A symmetrical double channel (3) is provided in a central part of the front side of the heater and this channel extends over part of the height or length of this side of the heater. The channel is formed by deflectors (3a, 3b) oriented towards the left and right sides of the heater or towards the top and bottom sides of the heater. A flow of hot air is generated by a ventilation box (4) connected to a conduit (6) integrated into the heater casing (1), the conduit being provided with two rows of holes (7) oriented in the direction of the deflectors. Hot air leaves the conduit via these holes and is distributed via the channel so that it follows two substantially parallel towels (10) located on the front side of the heater. The front side of the heater is vertical and includes at least one horizontal towel rail (9). The heater is an electric one.
Patent DK-1509565-T3 (DK)
Inventor: HASSKERL THOMAS
IPC: C08J7/046
Filed: 2003-05-20
Granted: 2006-07-10
Abstract: The invention relates to self-cleaning synthetic bodies, obtained as follows: a) a siloxane coating (a) is applied to a synthetic substrate and cured, b) the polar fraction of the surface energy of the cured siloxane coating on the substrate is increased to a value of at least 10 mN/m and c) a coating (b) containing photocatalytically active TiO2 particles is applied to the synthetic substrate and cured.
Patent DK-1487466-T3 (DK)
Inventor: FIORAMONTI JEAN
IPC: A23L29/00
Filed: 2003-03-21
Granted: 2008-05-19
Abstract: The invention relates to the use of lactic bacteria of the species Lactobacillus farciminis for the treatment or prevention of a pathology of the digestive tube, especially an acute or chronic inflammatory pathology of the intestine.
Patent DK-1682357-T3 (DK)
Inventor: LEUTE KURT
IPC: B42F13/24
Filed: 2004-09-11
Granted: 2008-03-17
Abstract: The invention relates to a binder mechanism for record binders. The binder mechanism comprises a base plate (10) having two interspaced aligning pins (12', 12''), a pivotal arched element (18) and an actuating lever (22), which is pivotally mounted on an end shield (20) of the base plate (10) and which acts upon a spring-supported bend (26) of the arched element (18). The actuating lever (22) can be locked in a first and a second open position of a respective detent part (52, 56), which is situated on a hold-down element (28), under the action of the return spring (24) on the bend (26) of the bearing web (14). In order to achieve a reliable locking also in the first open position (52) corresponding to a customary actuation, the width of the insertion gap (68) between aligning pins (12',12'') and the arched element (18) is reduced on the pivot path of the actuating lever (22) between both open positions while increasing the pretensioning of the return spring (24) in places under the passage measure for the actuating lever (22).
Patent DK-1723002-T3 (DK)
Inventor: MCLENAGHAN ALAN
IPC: B60P3/00
Filed: 2005-02-23
Granted: 2009-07-06
Abstract: The method involves providing a folded container (20) on recovery locations in a vehicle (1) e.g. truck, that delivers glass plates. The glass plates rest on a stand (3) and the container is inserted in free layer of the stand. The container is brought back as unfolded and filled with wastes recovered in the vehicle during its return path, while occupying the location of the glass plates in depart path. An independent claim is also included for a container for recovering and transporting glass cullet.
Patent DK-1730494-T3 (DK)
Inventor: BUECHS JOCHEN
IPC: B01L99/00
Filed: 2005-03-18
Granted: 2009-08-03
Abstract: The invention relates to a method and a device for the recording of process parameters of reaction fluids in several microreactors which are continuously agitated, at least until the termination of the reaction in all the microreactors. The process parameters in the microreactor are recorded during the reaction by means of at least one sensor optical system. According to the invention, the reliability of the method may be increased, whereby, during the recording of the value of a process parameter, for example, on recording an instantaneous value of the auto-fluorescence of the reaction fluids, the sensor optical system is held stationary. The relative movement of the agitated microreactor and each sensor optical system thus produced is not problematical when the electromagnetic radiation from each sensor optical system is introduced exclusively into one of the microreactors concerned during the recording of the process parameter in said microreactor and the radiation emitted from the reaction fluid is only incident on the sensor of the corresponding sensor optical system.
Patent DK-1800133-T3 (DK)
Inventor: STASSAR MARIKE JOSEE JANNEKE GERTRUD
IPC: C40B30/04
Filed: 2005-10-07
Granted: 2011-03-28
Abstract: The present invention provides an improved method of screening a library of molecules to identify or select one or more members thereof which are candidate binding partners for one or more target entities: (a) contacting an expression library with one or more target entities; (b) subjecting said target entities to at least one washing step; (c) separating target entities which have become bound to one or more members of the expression library from unbound members of the expression library by separation through an organic phase, thereby separating candidate binding partners for said target entities from other library members.
Patent DK-1862802-T3 (DK)
Inventor: KRUSE ULRICH
IPC: G01N33/574
Filed: 2006-06-01
Granted: 2009-04-14
Abstract: The invention provides in a first aspect a method for the identification of an ZAP-70 interacting compound, comprising the steps of a) providing a protein preparation containing phosphorylated ZAP-70, b) contacting the protein preparation with aminopyrido-pyrimidine ligand 24 immobilized on a solid support under conditions allowing the formation of an aminopyrido-pyrimidine ligand 24 - phosphorylated ZAP-70 complex, c) incubating the aminopyrido-pyrimidine ligand 24 - phosphorylated ZAP-70 complex with a given compound, and d) determining whether the compound is able to separate phosphorylated ZAP-70 from the immobilized aminopyrido-pyrimidine ligand 24. In a second aspect, the present invention relates to A method for the identification of an ZAP-70 interacting compound, comprising the steps of a) providing a protein preparation containing phosphorylated ZAP-70, b) contacting the protein preparation with ligand aminopyrido-pyrimidine ligand 24 immobilized on a solid support and with a given compound under conditions allowing the formation of an aminopyrido-pyrimidine ligand 24 - phosphorylated ZAP-70 complex, and c) detecting the aminopyrido-pyrimidine ligand 24 - phosphorylated ZAP-70 complex formed in step b). In a third aspect, the invention provides a method for the identification of an ZAP-70 interacting compound, comprising the steps of: a) providing two aliquots of a protein preparation containing phosphorylated ZAP-70, b) contacting one aliquot with aminopyrido-pyrimidine ligand 24 immobilized on a solid support under conditions allowing the formation of an aminopyrido-pyrimidine ligand 24 - phosphorylated ZAP-70 complex, c) contacting the other aliquot with aminopyrido-pyrimidine ligand 24 immobilized on a solid support and with a given compound under conditions allowing the formation of an aminopyrido-pyrimidine ligand 24 - phosphorylated ZAP-70 complex, and d) determining the amount of aminopyrido-pyrimidine ligand 24 - phosphorylated ZAP-70 complex formed in steps b) and c). In a forth aspect, the invention relates to a method for the identification of an ZAP-70 interacting compound, comprising the steps of: a) providing two aliquots comprising each at least one cell containing phosphorylated ZAP-70, b) incubating one aliquot with a given compound, c) harvesting the cells of each aliquot, d) lysing the cells in order to obtain protein preparations, e) contacting the protein preparations with aminopyrido-pyrimidine ligand 24 immobilized on a solid support under conditions allowing the formation of an aminopyrido-pyrimidine ligand 24 - phosphorylated ZAP-70 complex, and f) determining the amount of aminopyrido-pyrimidine ligand 24 - phosphorylated ZAP-70 complex formed in each aliquot in step e).
Patent DK-1899940-T3 (DK)
Inventor: NEKULA LAMBERT
IPC: B32B15/12
Filed: 2006-06-22
Granted: 2010-11-08
Abstract: The invention relates to a process for producing a carrier material with at least one hidden identification mark which is attached in at least one surface region of the carrier material and which is then covered. The invention furthermore relates to articles containing this carrier material and its use for analysis of the identification mark(s). By the process as claimed in the invention a carrier material with hidden identification marks is made available, the use of which is given in a wide range, especially when the original state of goods is to be established. For the consumer itself the identification mark is not necessarily visible so that he is not unnecessarily upset, but rather is confronted with a conventional decoration, specifically an embossing pattern. If necessary, such as for example in customs controls, the identification mark however can be easily exposed by depression so that analysis of the packaged product with respect to originality can take place.