baber/WOPTO huggingface dataset:
Patent WO-2019060685-A1 (WO)
Title: System and method of phenotype and polynucleotide sequencing analyses for biological particles via deterministic barcoding
Inventor: ANDREYEV DMITRY
IPC: C12P19/34
Filed: 2018-09-21
Abstract: A system and method for analyzing a phenotype and polynucleotide sequences of a biological particle. The biological particle is optically analyzed by a phenotype analyzer, such as a flow cytometer, to determine a phenotype of the biological particle. A oligonucleotide barcode carrier is generated with the oligonucleotide barcode attached to the carrier. The oligonucleotide barcode has a pre-defined sequence. The biological particle and the oligonucleotide barcode carrier are passed to a microreactor where the biological particle is lysed to release the polynucleotides of the biological particle. The oligonucleotide barcode is ligated to the polynucleotides of the biological particle to form a genetic complex. The resulting genetic complex is sequenced, and the phenotype of the biological particle is matched to the sequence of the polynucleotides of the biological particle.
Patent WO-2019067404-A1 (WO)
Title: Flumioxazin compositions and methods of use thereof
Inventor: ZHOU KE
IPC: A01N43/54
Filed: 2018-09-25
Abstract: The present invention is direcied to flumioxazin suspension concentrates containing a polyoxyethylene polyarylphenol phosphate or phosphate ester acid salts thereof. The present invention is further directed tο a method of controlling weeds by applying compositions of the present invention.
Patent WO-2019067740-A1 (WO)
Title: Fusion proteins having a toxin and cancer marker, nanoparticles, and uses related thereto
Inventor: YANG LILY
IPC: A61P35/00
Filed: 2018-09-27
Abstract: This disclosure relates to nanoparticles coated with fusion proteins comprising a domain that binds a cancer marker and a domain comprising a toxic polypeptide. In certain embodiments, the targeted cancer marker is urokinase plasminogen activator receptor (uPAR) insulin-like growth factor 1 receptor (IGF1R), EGFR, HER2, and/or other member of the ErbB family of receptors. In certain embodiments, the molecule that binds a cancer marker is an amino terminal fragment of uPA or variant capable of binding uPAR and/or IGF1 or variant capable of binding IGF1R. In certain embodiments, the toxic polypeptide is a bacterial exotoxin.
Patent WO-2019071147-A1 (WO)
Title: P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd
Inventor: CACACE ANGELA MARIE
IPC: A61K31/53
Filed: 2018-10-05
Abstract: The disclosure relates to methods and compositions including p38 kinase inhibitors and agents that regulate expression of DUX4 and downstream genes including but not restricted to ZSCAN4, LEUTX, PRAMEF2, TRIM43, MBD3L2, KHDClL, RFPL2, CCNAl, SLC34A2, TPRXl, PRAMEF20, TRIM49, PRAMEF4, PRAME6, PRAMEFl5, or ZNF280A. Methods useful for treating a disease associated with abnormal DUX4 and downstream gene expression (e.g., Fascioscapulohumeral muscular dystrophy) are disclosed.
Patent WO-2019083914-A1 (WO)
Inventor: LU GANG
IPC: C09J183/04
Filed: 2018-10-23
Abstract: L'invention concerne un polymère de siloxane, comprenant un squelette des unités de répétition siloxane suivantes et des agrégats de groupes terminaux formés à partir d'unités siloxane. Les agrégats sont fonctionnalisés par la présence d'au moins deux groupes réactifs fonctionnels par agrégat, au moins un groupe réactif fonctionnel étant un groupe polymérisable par radicaux libres et au moins un groupe réactif fonctionnel étant un groupe alcénylalcoxysilane, et la quantité de groupes polymérisables par radicaux libres étant d'au moins 2 % en moles des moles totales des groupes réactifs fonctionnels dans le polymère. L'invention concerne également un adhésif produit à l'aide de tels polymères.
Patent WO-2019084237-A1 (WO)
Inventor: RUSSIN TIMOTHY
IPC: G03F7/20
Filed: 2018-10-25
Abstract: Selon la présente invention, un procédé de mise au point consiste à exposer un objet par orientation d'une sortie de rayonnement par une source de rayonnement à travers une lentille d'objectif, par mesure d'une première intensité de rayonnement réfléchi qui est réfléchie par l'objet, par réglage d'une distance entre la lentille d'objectif et l'objet, par mesure d'une seconde intensité de rayonnement réfléchi, et par analyse de la première intensité de rayonnement réfléchi et de la seconde intensité de rayonnement réfléchi afin de déterminer une distance focale entre la lentille d'objectif et l'objet. La distance entre la lentille d'objectif et l'objet est réglée par rapport à la distance focale et l'intensité d'exposition est augmentée pour marquer l'objet. Dans un autre exemple, la mesure de la première intensité de rayonnement réfléchi est effectuée par orientation d'un rayonnement réfléchi à partir de l'objet à travers la lentille d'objectif, un diviseur de faisceau, une lentille de mise au point, et un trou d'épingle et sur un capteur qui produit un signal indicatif de l'intensité de rayonnement détectée.
Patent WO-2019084482-A1 (WO)
Inventor: MICHALAK NICHOLAS
IPC: A61F5/56
Filed: 2018-10-26
Abstract: L'invention concerne un procédé de traitement d'une affection respiratoire qui comprend les étapes consistant à se munir d'une bandelette de visage ayant une couche adhésive et une couche de maille disposée sur la couche adhésive et à appliquer la couche adhésive à la bouche d'un patient auquel on a diagnostiqué une affection respiratoire comprenant bouche sèche, mal de gorge, congestion nasale et/ou hypoxie. Le procédé comprend en outre les étapes consistant à recouvrir la bouche du patient avec la bandelette de visage et à fournir une résistance à partir de la bandelette de visage au niveau de la bouche du patient, et à augmenter la respiration nasale avec la bandelette de visage. La bandelette de visage réduit ou empêche l'incidence de l'affection respiratoire.
Patent WO-2019094613-A1 (WO)
Title: Procédé de traitement du cancer du sein et de maladies chroniques
Inventor: HUDSON BARRY
IPC: A61K38/00
Filed: 2018-11-08
Abstract: L'invention concerne un procédé de traitement du cancer du sein, le procédé comprenant l'administration à un Sujet mammifère Qui En a besoin d'un inhibiteur du récepteur Pour un produit final de Glycation avancée (RAGE). L'invention concerne en outre un procédé d'inhibition de la métastase du cancer du sein, le Procédé comprenant l'administration à un sujet mammifère qui en a besoin d'un inhibiteur de RAGE.
Patent WO-2019118885-A1 (WO)
Inventor: LEUNG WAI-HANG
IPC: C07K14/705
Filed: 2018-12-14
Abstract: The present disclosure provides improved compositions for adoptive T cell therapies targeting NKG2D ligands for treating, preventing, or ameliorating at least one symptom of a cancer, infectious disease, autoimmune disease, inflammatory disease, and immunodeficiency, or condition associated therewith.
Patent WO-2019126322-A1 (WO)
Title: Neurotoxines destinées à être utilisées pour réduire au minimum la formation de cicatrices
Inventor: ABUSHAKRA SAWSAN
IPC: A61K9/00
Filed: 2018-12-19
Abstract: L'invention concerne également des procédés pour réduire au minimum la formation de cicatrice pendant le processus de cicatrisation des plaies. L'invention concerne également des procédés pour améliorer l'aspect d'une cicatrice qui se forme sur une plaie. Les procédés comprennent l'administration d'une quantité thérapeutiquement efficace de Sous-Type E de toxine botulique (BoNT/E) à proximité d'une plaie.
Patent WO-2019133404-A1 (WO)
Title: Systems and methods for portable pill dispensers with various dispensing mechanisms
Inventor: CROWLEY CHRIS
IPC: A61J7/00
Filed: 2018-12-20
Abstract: Portable pill dispensers are disclosed herein. The portable pill dispenser may include a container configured to house at least one pill therein, a housing attachable to the container, and a dispensing mechanism disposed within the housing. In one configuration, the dispensing mechanism includes an oscillating member configured to dispense the at least one pill from the container.
Patent WO-2019126639-A1 (WO)
Title: Récepteurs d'antigènes chimériques comprenant une séquence d'épitope de transferrine humaine
Inventor: WU LIJUN
IPC: C12N5/071
Filed: 2018-12-21
Abstract: La présente invention concerne une protéine de fusion du récepteur d'antigène chimérique comprenant : (i) un fragment variable à chaîne unique (scFv) comprenant VH et VL, le scFv présentant une activité contre un antigène tumoral, (ii) un domaine transmembranaire, (iii) au moins un domaine de co-stimulation, et (iv) un domaine d'activation ; le CAR comprenant en outre un fragment de transferrine humaine, qui est un épitope pour un anticorps contre la transferrine humaine, à une extrémité N-terminale ou C-terminale du scFv, ou entre VH et VL. Les antigènes tumoraux préférés sont CD19, CD22 et BCMA. Les lymphocytes T CD19-TF-CAR, les lymphocytes T CD22-TF-CAR et les lymphocytes T BAMA-TF-CAR sécrètent moins de cytokines, mais ont la même efficacité contre les cellules cibles cancéreuses, comparées au même CAR sans TF.
Patent WO-2019135998-A1 (WO)
Title: Appareil de support de sécurité
Inventor: HENDRICKS JAMES
IPC: B60P1/00
Filed: 2018-12-28
Abstract: Des modes de réalisation de la présente invention concernent un appareil de support de sécurité destiné à des plates-formes de camion élevées dans une position levée. Le fond de l'appareil de support de sécurité fournit une plate-forme de support, un mécanisme de serrage qui s'ajuste sur des éléments de châssis du camion fournissant des rails d'épaisseurs variables. La partie supérieure de l'appareil de support de sécurité fournit un récepteur qui peut être conçu avec plusieurs éléments modulaires pour venir en prise avec la partie inférieure d'une plate-forme de camion élevée.
Patent WO-2019140077-A1 (WO)
Title: System and method for prepaid purse drive payments
Inventor: BUCKLEY ANDREW
IPC: G06Q20/34
Filed: 2019-01-10
Abstract: A prepaid spending card for the storage of funds, the prepaid spending card comprising a single primary account number. The prepaid spending card further comprises a first purse identified by a first pseudo DDA, the first purse authorized to received funds from any available funding source, and a second purse identified by a second pseudo DDA, the second purse authorized to send and receive funds only from restricted sources. The first pseudo DDA is used to route incoming funds to the first purse and the second pseudo DDA is used to route incoming funds to the second purse. Moreover, the first purse receives funds from any available funding source and the second purse receives from restricted funding sources.
Patent WO-2019143782-A1 (WO)
Title: Pvc plasticizers and methods for making thereof
Inventor: WEI XIANGYUN
IPC: C08K5/00
Filed: 2019-01-17
Abstract: A plasticized PVC composition free of phthalate is disclosed. The composition comprises a tertiary diamide plasticizer prepared from biorenewable feedstock such as fatty acid selected from tall oil fatty acids, tall oil fatty acid monomers, fatty acids derived from tall oil fatty acid, and mixtures thereof. The tertiary diamide plasticizer is a reaction product of a reactant mixture comprising the fatty acid and one or more monocyclic diamines.
Patent WO-2019157445-A1 (WO)
Title: Biomolecular probes and methods of detecting gene and protein expression
Inventor: BEECHEM JOSEPH
IPC: C12Q1/6841
Filed: 2019-02-11
Abstract: The present invention relates to, among other things, probes, compositions, methods, and kits for simultaneous, multiplexed detection and quantification of protein and/or nucleic acid expression in a user-defined region of a tissue, user-defined cell, and/or user-defined subcellular structure within a cell that are adaptable for use with existing sequencing technologies.
Patent WO-2019161098-A1 (WO)
Title: Jak1 pathway inhibitors for the treatment of cytokine-related disorders
Inventor: O'NEILL MONTGOMERY MICHAEL
IPC: A61K31/437
Filed: 2019-02-14
Abstract: This disclosure relates to JAK1 pathway inhibitors and the use thereof in treating cytokine-related diseases or disorders such as cytokine release syndrome (CRS), hemophagocytic lymphohistiocytosis (HLH), macrophage activation syndrome (MAS), and CAR-T-cell-related encephalopathy syndrome (CRES).
Patent WO-2019161137-A1 (WO)
Title: Aluminum alloy products and methods for producing the same
Inventor: LIN JEN C
IPC: C22F1/05
Filed: 2019-02-14
Abstract: The present disclosure relates to new aluminum alloy products. In one embodiment, an aluminum alloy product comprises at least one of (i) equiaxed grains, (ii) an average grain size of not greater than 50 micrometers, (iii) at least 10 vol. % of a eutectic-type structure, and (iv) a eutectic-type structure having an average eutectic-type structure spacing of not greater than 5.0 micrometers. In one embodiment, the aluminum alloy products may realize a non- equilibrium freezing range of not greater than 200°C. In one embodiment, the aluminum alloy products may be one of an Al-Li-Si or Al-Mg-Si aluminum alloy product.
Patent WO-2019169279-A1 (WO)
Inventor: SALMIA LAURI
IPC: H02M5/45
Filed: 2019-03-01
Abstract: Unique systems, methods, techniques and apparatuses of power amplifiers are disclosed. One exemplary embodiment is a power system for an active magnetic bearing including at least one power amplifier. Each power amplifier includes a first semiconductor device including a first node coupled to a neutral point node and a second node, a second output node coupled to the neutral point node, a second semiconductor device including a first node coupled to the second node of the first semiconductor device and a second node coupled to a first output node, a third semiconductor device including a first node coupled to a first DC bus node and a second node coupled to the first output node, and a fourth semiconductor device including a first node coupled to a second DC bus node and a second node coupled to the second node of the first semiconductor device.
Patent WO-2019194927-A1 (WO)
Title: Control information combining techniques in wireless communications
Inventor: ZHOU YAN
IPC: H04L5/00
Filed: 2019-03-06
Abstract: Methods, systems, and devices for wireless communications are described that provide for transmissions of multiple instances of control information, such as remaining minimum system information (RMSI), that may be used for system access by a user equipment (UE). The multiple instances of the control information may be combined at the UE to enhance the likelihood of successful decoding of the control information. A base station may transmit an indication that combining of multiple instances of control information is supported by the base station, and may transmit the multiple instances of control information via configured downlink transmission resources. A UE may receive the indication that combining of multiple control information instances is supported, may identify two or more instances within downlink transmission resources configured for control information transmissions, and may combine signals received in each of the two or more instances to generate a combined control information signal.
Patent WO-2019190765-A1 (WO)
Inventor: Morales Delgado Edgar Emilio
IPC: A61B5/00
Filed: 2019-03-14
Abstract: An imaging device includes an image pixel array and a display pixel array. The image pixel array is configured to capture an infrared image of an interference between an infrared imaging signal and an infrared reference wavefront. The display pixel array is configured to generate an infrared holographic imaging signal according to a holographic pattern driven onto the display pixels. The holographic pattern is derived from the infrared image captured by the image pixel array.
Patent WO-2019195027-A1 (WO)
Title: Automated vertical farming system using mobile robots
Inventor: LERT JOHN G JR
IPC: A01G31/04
Filed: 2019-03-26
Abstract: A vertical farming system is disclosed including a storage structure having racks of storage shelves for housing plant-carrying containers. Mobile robots travel around the racks to transfer containers of plants to and from the storage shelves. Under direction of a central control system, one or more mobile robots may transport a container from a storage location to a workstation. Once there, care may be provided for the plant, including water and/or other nutrients, and data may be gathered on the plant. This may be done by an owner of the plant, or by an automated service robot positioned at the workstation. Data gathered on the plant, including for example photographs, may be sent by email or other communications schemes to an owner of the plant.
Patent WO-2019191302-A1 (WO)
Title: Laminated glass structures for electronic devices and electronic device substrates
Inventor: KIM JIN SU
IPC: B32B7/02
Filed: 2019-03-27
Abstract: A laminated glass structure for an electronic device includes: a core glass layer having a first coefficient of thermal expansion (CTE); and a plurality of clad glass layers, each having a CTE that is lower than or equal to the first CTE of the core glass layer. A first of the clad glass layers is laminated to a first surface of the core glass layer and a second of the clad layers is laminated to a second surface of the core glass layer. Further, the total thickness of the core glass layer and the clad glass layers ranges from about 0.1 mm to about 3 mm. In addition, each of the first of the clad layers and the core glass layer comprises a loss tangent of 0.006 or less for signals having a frequency of 1 GHz to about 100 GHz.
Patent WO-2019210303-A1 (WO)
Inventor: XU FELIX JUEFEI
IPC: G06K9/46
Filed: 2019-04-29
Abstract: La présente invention concerne un procédé pour améliorer des itérations suivantes d'un réseau génératif par addition d'une perte de classement à la perte totale pour le réseau, la perte de classement représentant la différence marginalisée entre un score de discriminateur pour une image générée dans une itération du réseau génératif et le score de discriminateur pour une image réelle provenant d'une itération suivante du réseau génératif.
Patent WO-2019213043-A1 (WO)
Title: Antibodies with modulated glycan profiles
Inventor: CROWELL CHRISTOPHER
IPC: A61K39/395
Filed: 2019-04-30
Abstract: This invention relates to recombinantly-expressed denosumab molecules and methods for modulating glycan profiles of denosumab molecules.
Patent WO-2019217632-A1 (WO)
Title: Turbine control system
Inventor: LOPEZ CAMILO
IPC: G01P3/44
Filed: 2019-05-09
Abstract: A turbine control system is provided for decreasing the response time between readings of the speed of the turbine and changing a valve position in response thereto. The speed control system includes a speed probe that detects the speed of the turbine and a turbine valve that controls the flow of fluid or gas from or to the turbine. A controller receives a speed signal from the speed probe and sends valve position commands to the turbine valve. The controller also sends support functions to the turbine valve. The controller sends the valve position commands at a faster rate than the support functions.
Patent WO-2019226549-A1 (WO)
Title: Computer generated hair groom transfer tool
Inventor: KURIBAYASHI TAKASHI
IPC: G06T13/80
Filed: 2019-05-20
Abstract: A computer generated (CG) hair groom for a virtual character can include strand-based (also referred to as instanced) hair in which many thousands of digital strands represent real human hair strands. Embodiments of systems and methods for transferring CG hair groom data from a first (or source) virtual character to a second (or target) virtual character are provided. Some embodiments can factor in a difference between a hairline of the first virtual character and a hairline of the second virtual character to improve the overall appearance or fit of the hair groom on the second virtual character.
Patent WO-2019232529-A1 (WO)
Title: Smoothness constraint for camera pose estimation
Inventor: HOU XIAODI
IPC: G06K9/00
Filed: 2019-06-03
Abstract: Disclosed are devices, systems and methods for incorporating a smoothness constraint for camera pose estimation. One method for robust camera pose estimation includes determining a first bounding box based on a previous frame, determining a second bounding box based on a current frame that is temporally subsequent to the previous frame, estimating the camera pose by minimizing a weighted sum of a camera pose function and a constraint function, where the camera pose function tracks a position and an orientation of the camera in time, and where the constraint function is based on coordinates of the first bounding box and coordinates of the second bounding box, and using the camera pose for navigating the vehicle. The method may further include generating an initial estimate of the camera pose is based on a Global Positioning System (GPS) sensor or an Inertial Measurement Unit (IMU).
Patent WO-2020005498-A1 (WO)
Title: Wine display
Inventor: DI PRIMA PAOLO
IPC: A47B73/00
Filed: 2019-06-06
Abstract: A system and method for a rack. The rack has at least one shelf which has at least two longitudinal rails. The rails each have an upper end and a lower end. The upper end is coupled to a mount. The longitudinal rails are separated by a void and are further coupled to a lip at the end. The longitudinal rails are angled relative to said mount at an angle less than 90 degrees. In one vertical rack, the mount is sandwiched between a base support and a neck support, with each support having a void to receive a bottle.
Patent WO-2019241047-A1 (WO)
Title: Friend key sharing
Inventor: GALDO FLORIAN
IPC: B60R25/20
Filed: 2019-06-07
Abstract: Techniques are disclosed relating to sharing access to electronically-secured property. In some embodiments, a first computing device having a first secure element receives, from a second computing device associated with an owner of the electronically-secured property, an indication that the second computing device has transmitted a token to server computing system, the token permitting a user of the first computing device access to the electronically-secured property. Based on the received indication, the first computing device sends a request for the transmitted token to the server computing system and, in response to receiving the requested token, securely stores the received token in the first secure element of the first computing device. The first computing device subsequently transmits the stored token from the first secure element of the first device to the electronically-secured property to obtain access to the electronically-secured property based on the token.
Patent WO-2019241372-A1 (WO)
Title: Alkali metal-sulfur secondary battery containing cathode material particulates
Inventor: ZHAMU ARUNA
IPC: H01M10/052
Filed: 2019-06-12
Abstract: Provided is a rechargeable alkali metal-sulfur cell comprising an anode active material layer, an electrolyte, and a cathode active material layer comprising multiple particulates, wherein at least one of the particulates comprises one or a plurality of sulfur-containing material particles being embraced or encapsulated by a thin layer of a conductive sulfonated elastomer composite having from 0.01% to 50% by weight of a conductive reinforcement material dispersed in a sulfonated elastomeric matrix material, wherein the conductive reinforcement material is selected from graphene sheets, carbon nanotubes, carbon nanofibers, metal nanowires, conductive polymer fibers, or a combination thereof and the composite has a recoverable tensile strain from 2% to 500%, a lithium ion conductivity from 10 -7  S/cm to 5 x 10 -2  S/cm, and a thickness from 0.5 nm to 10 µm. This battery exhibits an excellent combination of high sulfur content, high sulfur utilization efficiency, high energy density, and long cycle life. The disclosure also provides a method of producing a rechargeable alkali metal-sulfur cell.