baber/WOPTO huggingface dataset:
Patent EA-004800-B1 (EA)
Title: Treatment of diabetes with rosiglitazone and insulin
Inventor: SMITH STEPHEN ALISTAIR
IPC: A61K38/28
Filed: 1998-06-15
Abstract: 1. A composition comprising from 2 to 12 mg 5-[[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidyl-2,4-dione of Compound (I) or a pharmaceutically acceptable form and insulin for the treatment of diabetes of type 2 and conditions associated with diabetes type 2. 2. The composition according to claim 1, comprising from 2 to 4 mg, from 4 to 8 mg or from 8 to 12 mg of Compound (I) or a pharmaceutically acceptable form. 3. The composition according to claim 1 or 2, comprising from 2 to 4 mg of Compound (I) or a pharmaceutically acceptable form. 4. The composition according to claim 1 or 2, comprising from 4 to 8 mg of Compound (I) or a pharmaceutically acceptable form. 5. The composition according to claim 1 or 2, comprising from 8 to 12 mg of Compound (I) or a pharmaceutically acceptable form. 6. The composition according to any one of claims 1-3, comprising 2 mg of Compound (I) or a pharmaceutically acceptable form. 7. The composition according to any one of claims 1-4, comprising 4 mg of Compound (I) or a pharmaceutically acceptable form. 8. The composition according to any one of claims 1, 2, 4 and 5, comprising 8 mg of Compound (I) or a pharmaceutically acceptable form. 9. The composition according to any one of claims 1-8, wherein Compound (I) or pharmaceutically acceptable form thereof and insulin are prepared in the form of one pharmaceutical composition dosage. 10. The composition according to any one of claims 1-9, wherein Compound (I) or pharmaceutically acceptable form thereof and insulin are represented in the form of separate pharmaceutical compositions. 11. A pharmaceutical composition comprising from 2 to 12 mg 5-[[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidyl-2,4-dione of Compound (I) or a pharmaceutically acceptable form and insulin for the treatment of diabetes of type 2 and conditions associated with diabetes type 2. 12. Use from 2 to 12 mg 5-[[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidyl-2,4-dione of Compound (I) or a pharmaceutically acceptable form and insulin for the manufacturing a medicament for use in the treatment of diabetes of type 2 and conditions associated with diabetes type 2. 13. Use from 2 to 12 mg 5-[[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidyl-2,4-dione of Compound (I) or a pharmaceutically acceptable form and insulin for the manufacturing a medicament for use with insulin in the treatment of diabetes of type 2 and conditions associated with diabetes type 2. 14. Use insulin for manufacturing a medicament for use from 2 to 12 mg 5-[[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidyl-2,4-dione of Compound (I) or a pharmaceutically acceptable form for the treatment of diabetes of type 2 and conditions associated with diabetes type 2.
Patent EA-005840-B1 (EA)
Title: Wellbore internally oriented perforating system
Inventor: SLOAN MARK L
IPC: E21B43/119
Filed: 2002-11-27
Abstract: One embodiment of the present invention discloses a system and method for orienting perforating guns inside of slanted or deviated wellbores. The invention involves adding a weight inside of the guns to gravitate the gun to a specified orientation. The weight is situated on the outer circumference of the gun tube and within the inner diameter of the gun body. The invention is capable of orienting the gun in any radial position without affecting the shot performance of any of the shaped charges.
Patent EA-006174-B1 (EA)
Title: Marking of pipe joints
Inventor: DEN BOER JOHANNIS JOSEPHUS
IPC: E21B47/09
Filed: 2003-07-16
Abstract: An improved method of permanently marking the location of a tubular joint comprises creating a cavity (3) into the end surface of one of the tubular ends that are to be joined by a forge weld or screw thread connection, inserting a marker (4) into said cavity (3) and subsequently joining the tubular ends together.
Patent EA-009974-B1 (EA)
Title: Roulette game device and roulette game machine
Inventor: YOKITO TETSUYA
IPC: A63F5/02
Filed: 2005-08-16
Abstract: A roulette apparatus includes: a roulette wheel having a rolling region where a ball rolls; and a ball reception member provided contiguously to the rolling region to receive the ball. The ball reception member includes: a plurality of reception portions that receives the ball in one of the reception portions;and a plurality of separation walls that separates the reception portions from one another, wherein the ball reception member is formed separately from the roulette wheel and removably attached to the roulette wheel.
Patent EA-011177-B1 (EA)
Title: Additive for reducing torque on a drill string
Inventor: BRADBURY ANDREW
IPC: C10M171/06
Filed: 2006-02-22
Abstract: A method of reducing the torque of a drill string used in drilling a subterranean well that includes injecting into the drilling fluid a composition including a base fluid and a polymer coated colloidal solid material. The polymer coated colloidal solid material includes: a solid particle having an weight average particle diameter (d) of less than ten microns, and a polymeric dispersing agent coated onto the surface of the solid particle during the cominution (i.e. grinding) process utilized to make the colloidal particles. The polymeric dispersing agent may be a water soluble polymer having a molecular weight of at least 2000 Daltons. The solid particulate material may be selected from materials having of specific gravity of at least 2.68 and preferably the solid particulate material may be selected from barium sulfate (barite), calcium carbonate, dolomite, ilmenite, hematite, olivine, siderite, strontium sulfate, combinations and mixtures of these and other similar solids that should be apparent to one of skill in the art.
Patent EA-012884-B1 (EA)
Title: Method for producing insulin in the form of an oral preparation
Inventor: ARTAMONOV ANDREI VLADIMIROVICH
IPC: A61K38/28
Filed: 2007-09-11
Abstract: The invention relates to pharmacology and medicine, in particular to endocrinology. The inventive method consists in introducing insulin into a 1-50% aqueous solution of a polymer, the molar mass of which ranges from 0.4 to 40 kDa and which is pre-irradiated by an ionizing radiation dose of 1.0 to 5.0 Mrad, in such a way that the final concentration thereof ranges from 1 to 10 mg/ml at a ratio between polyethylene oxide and insulin equal to (1-500):1 and in agitating the mixture until a homogeneous transparent and slightly opalescent solution is obtained. Said method makes it possible to obtain a pharmaceutical composition comprising a biologically active insulin which exhibits a high hypoglycemic activity when enterally administered. The method provides simplification of oral insulin production and enhances therapeutic activity thereof.
Patent EA-014261-B1 (EA)
Title: Method for separating gases from solids in a gas-solids reaction system using a gas-solids flow
Inventor: BEECH JAMES H
IPC: B01J8/00
Filed: 2007-03-28
Abstract: A gas-solids reaction system is provided for improving product recovery in a multiple reactor reaction system. The solids of the product gas-solids flows from the multiple reactors are separated out in a separation vessel having a baffled transition zone. Additional product vapor is stripped from the solids as the solids pass through the baffled transition zone. The solids are then returned to the multiple reactors.
Patent EA-012005-B1 (EA)
Title: Transmitter
Inventor: NOGAMI TOSHIZO
IPC: H04W88/02
Filed: 2006-12-19
Abstract: A transmitter for transmitting a signal to a plurality of antennas includes: a transmission unit for giving an initial phase to an inputted signal by selecting the size of the initial phase for output to at least one of the antennas according to a communication time band and giving a delay for each of the antennas as the destination and for each communication time band or communication frequency; and a quality information reception unit for acquiring reception quality information on the signal transmitted by the transmission unit from a communication partner terminal.
Patent EA-015924-B1 (EA)
Title: Treatment of hiv
Inventor: MCINTOSH DEIRDRE
IPC: A61K38/095
Filed: 2007-01-05
Abstract: The invention describes methods of treatment of HIV using proopiomelanocortin (POMC) and corticotropin releasing factor (CRF) peptides and their products, as well as uses of such peptides in the preparation of medicaments.
Patent EA-013769-B1 (EA)
Title: Insulation system comprising interconnected insulation panels disposed against a wall
Inventor: WUTS PETER WILLEM
IPC: E04B1/74
Filed: 2007-02-21
Abstract: This invention relates to a wall system comprising a building wall with an insulating layer, said building wall (5) being the facade wall of a building or an inner wall, said insulating layer comprising insulation panels (3) each insulation panel (3) having first and second substantially parallel major surfaces (7,8). The second major surface (8) is facing the building wall, and the insulation panel (3) has at least three, preferably four, minor surfaces (9,9'), where a slit (10) is made in a minor surface and extending substantially parallel with the major surfaces (7,8). The insulation panel (3) is positioned between at least two profiles (4), each profile having a base portion (13) substantially parallel with and in contact with a part of one minor edge surface (9) of the insulation panel (3) and a flange portion (11) substantially parallel with the major surfaces (7,8) of the insulation panel (3) and extending into said slit (10) in the minor surface (9') of the insulation panel (3). The insulation panel (3) having a thickness larger than a width of the base portion (13) of the profiles (4), and at least one profile (4) is arranged and fastened to parts of the building different from the building wall (5), so that no elements connected to said profile (4) except the insulation panel (3) span from the first major surface (7) of the insulation panel (3) to the second major surface (8) of the insulation panel (3).
Patent EA-016041-B1 (EA)
Title: Methods of using gpr119 receptor to identify compounds useful for increasing bone mass in an individual
Inventor: CHU ZHI-LIANG
IPC: G01N33/50
Filed: 2007-04-10
Abstract: The present invention relates to methods of using GPR119 receptor to identify compounds useful for increasing bone mass in an individual. Agonists of GPR119 receptor are useful as therapeutic agents for treating or preventing a condition characterized by low bone mass, such as osteoporosis, and for increasing bone mass in an individual. Agonists of GPR119 receptor promote bone formation in an individual.
Patent EA-017095-B1 (EA)
Title: Method of leaching zinc from copper-sulphide concentrate
Inventor: TIIHONEN JARI
IPC: C22B3/08
Filed: 2008-09-03
Abstract: The invention relates to a method for the preparation of a copper concentrate suitable for pyrometallurgical treatment from a concentrate in which zinc is present as an impurity. In accordance with the method, zinc is leached from the concentrate with a solution containing sulphuric acid at atmospheric pressure and temperature not exceeding 105°C, firstly in oxidizing conditions; before the end of the leach a reducing agent is fed into the leaching stage in order to precipitate the dissolved copper.
Patent EA-023530-B1 (EA)
Title: Orthopaedic splinting system
Inventor: PAERSSINEN ANTTI
IPC: A61L15/12
Filed: 2010-03-11
Abstract: A composite material in the form of a linear structure having a width, a length and a thickness, comprising a composite material with a first component formed by a polymer and a second component formed by a reinforcing material, wherein the first component comprises a thermoplastic polymer selected from the group of biodegradable polymers and mixtures thereof, and the second component comprises a woody material derived from platy or granular wood particles. The composite material being formable at a temperature of about 50 to 70°C and it can be used as a blank for an orthopedic splint.
Patent EA-025056-B1 (EA)
Title: Method for cultivation of hazel tree with the crown having the form of vertical spindle on the support
Inventor: MOULIS VLADO
IPC: A01G17/00
Filed: 2010-10-22
Abstract: Cultivation of hazel tree with the crown having the form of vertical spindle on the support represents the new way of planting and intensive cultivation of a hazel tree. Fig. 3 shows the plantation cultivation of hazel tree in double rows, which basic trees in the yield period have crowns in form of vertical cylinder or spindle shown in Fig. 1. A skeleton of the basic tree consists of a central line (1) without trunk, having on it radially arranged primary branches (2) and yielding branches (3). During the whole life of a basic tree there is done cutting of branches and forming the crown on the line that may grow up to 3 or 5 meters and external diameter of the spindle of a crown may be from 0,5 up to 1 meter. Because of poor firmness of a skeleton, basic trees are by means of lines (1) leant against supports (6). Such a form of hazel tree cultivation enables control of yielding potential in all parts of cultivation form, good illumination and photosynthesis, high rationality factor, as well as regular and good yield of high quality products.
Patent EA-024804-B1 (EA)
Title: Non-nucleoside reverse transcriptase inhibitors, compositions comprising them, and use thereof
Inventor: BURCH JASON
IPC: C07D401/06
Filed: 2011-03-28
Abstract: Heteroaromatic compounds of Formula (I) are reverse transcriptase inhibitors, wherein R, R, R, Rand Rare defined herein. The compounds of Formula (I) and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
Patent EA-024348-B1 (EA)
Title: Safe integrated locomotive complex
Inventor: VISKOV VLADIMIR VLADIMIROVICH
IPC: B61L25/04
Filed: 2013-09-12
Abstract: The invention relates to the field of railway automatics, remote control and communication systems, and can be used at DC and AC electric locomotives operated in passenger, high-speed and freight train traffic, and as a part of multi-level train separation systems. The technical result of the proposed invention is the expansion of functional capabilities. The safe integrated locomotive complex comprises the following components interconnected via an internal interface: a system cabinet, a locomotive indication unit, a registration unit comprising a registration cassette, a speed indication unit, a locomotive engine-driver's mate indication unit, an electro-pneumatic valve, an automatic locomotive signalling unit for point communication channel signals, rail signals receiving coils, a matching unit, and a driver vigilance control unit; connected to the external interface are: a microprocessor locomotive control system, a locomotive braking system, an electro-pneumatic valve and a filter, an additional interface connected to the system cabinet, an audio data board, the matching unit and the point communication channel receiver, the input of the latter being connected to one of the rail signals receiving coils, diagnostic equipment having its first, second and third ports connected, respectively, to the internal, external and additional interfaces, and the automatic locomotive point communication channel signalling unit includes a registration module for registering signals from the automatic locomotive signalling system, the first port of the named module being connected to an information reading and display device, and its second port being connected to the internal interface, the input of the registration module being connected to the rail signal receiving coils, and its output to the input of the receiver for receiving signals from the automatic locomotive signalling system, the system cabinet being connected to the information server through a communication channel via an integrated antenna.
Patent EA-030639-B1 (EA)
Title: Ho-based electrochemical hydrogen-catalyst power system
Inventor: MILLS RANDELL L
IPC: H01M8/06
Filed: 2012-03-30
Abstract: An electrochemical power system is provided that generates an electromotive force (EMF) from the catalytic reaction of hydrogen to lower energy (hydrino) states providing direct conversion of the energy released from the hydrino reaction into electricity, the system comprising at least two components chosen from the following: HO catalyst or a source of HO catalyst; atomic hydrogen or a source of atomic hydrogen; reactants to form the HO catalyst or source of HO catalyst and atomic hydrogen or source of atomic hydrogen; and one or more reactants to initiate the catalysis of atomic hydrogen. The electrochemical power system for forming hydrinos and electricity can further comprise a cathode compartment comprising a cathode, an anode compartment comprising an anode, optionally a salt bridge, reactants that constitute hydrino reactants during cell operation with separate electron flow and ion mass transport, and a source of hydrogen. Due to oxidation-reduction cell half reactions, the hydrino-producing reaction mixture is constituted with the migration of electrons through an external circuit and ion mass transport through a separate path such as the electrolyte to complete an electrical circuit. Further provided are a power source and hydride reactor that powers a power system comprising (i) a reaction cell for the catalysis of atomic hydrogen to form hydrinos, (ii) a chemical fuel mixture comprising at least two components chosen from: a source of HO catalyst or HO catalyst; a source of atomic hydrogen or atomic hydrogen; reactants to form the source of HO catalyst or HO catalyst and a source of atomic hydrogen or atomic hydrogen; one or more reactants to initiate the catalysis of atomic hydrogen; and a support to enable the catalysis, (iii) thermal systems for reversing an exchange reaction to thermally regenerate the fuel from the reaction products, (iv) a heat sink that accepts the heat from the power-producing reactions, and (v) a power conversion system.
Patent EA-030874-B1 (EA)
Title: Linear electromechanical actuator
Inventor: FEDOSOVSKY MIKHAIL EVGENIEVICH
IPC: F16H25/22
Filed: 2015-05-08
Abstract: The invention is related to the field of electromechanical actuators. Proposed is a linear electromechanical actuator comprising a housing, an electric motor including a stator (11) fixed on the inner surface of the housing, and a rotor. The actuator includes also a roller transmission that comprises a cylinder (16) with an internal thread, the cylinder being rotatable in the housing, a translationally movable rod (4) mounted in said cylinder, a screw (3) connected to the rod (4) without the possibility of mutual movement and having a threaded portion, and threaded rollers (2) that are mounted in said cylinder in engagement with the internal thread (16) of the cylinder and with the threaded portion of the screw (3) so that the force can be transmitted from said cylinder to the rod (4), capability of rotation of the cylinder of the roller transmission is ensured by mounting the cylinder in the housing on at least one bearing support. The electric motor rotor is formed by way of mounting magnets (12) on the external surface of the roller transmission cylinder; the actuator housing has at least one closable opening (17) for feeding a lubricant into the actuator housing, into the inner cavity of said cylinder with internal thread, and to said at least one bearing support; and at least one closable opening (19) for discharge of the lubricant material from said at least one bearing support and from the inner cavity of said cylinder with internal thread, which permits performing replacement of the actuator parts lubricant without the actuator disassembly or dismantling, thereby facilitating its maintenance and operation.
Patent EA-029852-B1 (EA)
Title: Vibrating grid based 3d space visualization device
Inventor: JEGER JOZSEF
IPC: G02B30/26
Filed: 2013-12-30
Abstract: The object of the present invention is a vibrating grid based space generating device, which enables 3D perception for the user, and which comprises a containing frame and image display surface, configured in such a manner that to the containing frame (1) a vibrating grid (10) is attached in a rotatable manner, which is equipped with vertically arranged matte black blocking strips (13) configured in a radial manner and focused into a vertical alignment, where the connecting elements (12) configured in the center line of the vibrating grid (10) join to the containing frame (1) so that when rotating the vibrating grid (10) in a horizontal direction on the containing frame (1), in the left and right side end positions of the distance of vibration (3), a 3D perception of earlier recorded images, alternating to the left (27) and right (28) eyes, displayed at an alternation rate of at least 24 images per second, displaced correspondingly to the interocular distance, is made possible on the image display surface (20) located behind the vibrating grid (10), while in the mid-position of the vibrating grid (10), which is the moment of the alternation of the image, the uniform dark left and right side surface is formed by the blocking strips (13) for the left (27) and right (28) eyes simultaneously.
Patent EA-030196-B1 (EA)
Title: Enhancer of zeste homolog 2 inhibitors
Inventor: BLACKLEDGE JR CHARLES WILLIAM
IPC: C07D413/14
Filed: 2014-04-25
Abstract: The present invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing such compounds, to processes for their preparation, and to their use in therapy for the treatment of cancer.
Patent ES-2272102-B1 (ES)
Title: Compuerta para aliviaderos de presas, que abre y cierra sola, sin necesitar suministro de energia externa.
Inventor: RODRIGUEZ GARCIA RAMON
IPC: E02B7/20
Filed: 2000-02-28
Granted: 2008-04-01
Abstract: Compuerta para aliviaderos de presas, que abre y cierra sola, sin necesitar suministro de energía externa, rotando sobre su eje (E) mediante momentos de giro horarios o antihorarios, inducidos por llenados y vaciados automáticos de su depósito, utilizando el agua que regula en su trasdós. Asimismo se desarrollan aplicaciones. El principal problema técnico en presas es el riesgo de las compuertas, pues si fallan accionamiento o suministro de energía, pueden provocar catástrofes. Por otro lado, los aliviaderos con compuertas son esenciales para regulación al maximizar la capacidad de embalses. La solución de compuerta aportada, con funcionamiento simple, robusto y autónomo, minimiza riesgos lo que favorece su aplicación en aliviaderos, optimizando la regulación de embalses.
Patent ES-2209620-B1 (ES)
Title: Pan de cava y procedimiento para su fabricacion.
Inventor: BALCELLS FERRES JOSEP
IPC: A21D13/40
Filed: 2002-05-31
Granted: 2005-10-01
Abstract: Pan de cava y procedimiento para su fabricación. Pan de cava que está constituido por 8.000 gramos de pasta madre a la que se adicionan 2.000 gramos de centeno, 10.000 gramos de harina, 160 gramos de levadura, 800 gramos de mantequilla, 3.750 mililitros de cava, 1.400 mililitros de agua y 320 gramos de sal y porque el procedimiento de fabricación comprende el amasado de todos los ingredientes citados en una máquina de amasar durante 10 minutos, formando una masa que, una vez extraída de la amasadora se deja reposar durante 60 minutos aproximadamente y posteriormente se trabaja conformándola en piezas que se dejan fermentar durante 90 minutos y que finalmente son introducidas en el horno para su cocción, pudiéndose congelar las piezas conformadas antes de su fermentación para su posterior comercialización en dicho estado.