baber/WOPTO huggingface dataset:
Patent CA-3135174-A1 (CA)
Title: Conjugues lies a hsp90 et formulations de ceux-ci
Inventor: WHITE BRIAN H
IPC: A61K31/4196
Filed: 2020-04-01
Abstract: Des conjugués d'un agent actif lié à une fraction de ciblage, telle qu'au moins une fraction de liaison à HSP90, par l'intermédiaire d'un lieur, ont été conçus. De tels conjugués peuvent produire la libération spatio-temporelle de l'agent actif, la biodistribution et la pénétration améliorées dans la tumeur, et/ou une toxicité réduite. Des procédés de préparation des conjugués et leurs formulations sont fournis. L'invention concerne en outre des méthodes d'administration des formulations à un sujet en ayant besoin, par exemple, pour traiter ou prévenir le cancer.
Patent CA-3135356-A1 (CA)
Inventor: ANDERSON TIMOTHY BENNET
IPC: E21B43/24
Filed: 2021-10-21
Abstract: A hydrocarbon recovery process for recovering hydrocarbons from a hydrocarbon-bearing formation includes preheating a pipe coupling a steam generation facility to a well for injection of steam into the hydrocarbon-bearing formation by controlling heat traces extending along the pipe, directing steam generated at the steam generation facility, through the pipe after preheating, and injecting the steam into the hydrocarbon-bearing formation via the well, and controlling heat input to the pipe by controlling the heat traces extending along the pipe as the steam travels through the pipe. Fluids are produced from the hydrocarbon-bearing formation.
Patent CA-3136380-A1 (CA)
Inventor: HU XUN
IPC: A63F13/426
Filed: 2020-11-13
Abstract: This application relates to the field of human-computer interaction, and in particular, to a method and an apparatus for skill aiming in a three-dimensional virtual environment, a device and a storage medium, which may solve the problem that how to improve the accuracy of ability aiming. Said method comprises: displaying a user interface of an application program; receiving a dragging operation on the skill aiming control, the dragging operation comprising a first operation point and a second operation point located on the skill aiming control; in response to the dragging operation, displaying a three-dimensional skill aiming indicator in the virtual environment picture, the skill aiming direction of the three-dimensional skill aiming indicator being parallel to the dragging direction of the dragging operation. In the present invention, the accuracy during ability aiming and the human-computer interaction efficiency is improved.
Patent CA-3136602-A1 (CA)
Inventor: STOVER DAVID
IPC: A61P35/00
Filed: 2020-04-15
Abstract: Fusion Protein compositions comprising masked IFNs and methods of making masked IFNs are disclosed herein. Consequently, the masked IFNs can be fused to a Mab or binding fragment thereof and be administered to patients as a therapeutic modality and provide a method of treating cancer, immunological disorders and other disease.
Patent CA-3137707-A1 (CA)
Title: Flexible container and process for installation of fitment in same
Inventor: WILKES KENNETH
IPC: B65B61/18
Filed: 2019-11-01
Abstract: A flexible container formed of flexible web material is provided. The container includes four panels forming: a body portion; a neck portion; a flare portion extending from the neck portion; and a tapered transition portion between the body and neck portions; wherein the neck portion has a reduced width and the flare portion has an expanded end. Also disclosed is a method of forming the aforementioned container comprising steps of: biasing the expanded end to define a circumference; moving, via a mandrel comprising a groove, the fitment within the circumference and through the expanded end to a first position in the neck; transversely cutting away the expanded end by advancing preferably v-shaped blades through the neck and into the groove preferably without rotation of the mandrel, container, or blades; moving the fitment to a second position in the neck; and sealing the neck to the fitment.
Patent CA-3140141-A1 (CA)
Inventor: WALDRON MICHAEL
IPC: G07F19/00
Filed: 2021-11-23
Abstract: In some implementations, a transaction device may include a display screen, at least one photosensitive sensor configured to detect a luminance of a viewing surface of the display screen, and one or more processors. The one or more processors may be configured to monitor an output of the at least one photosensitive sensor, determine that the output is indicative of an obstruction on the display screen based on the output indicating a change to the luminance of the viewing surface of the display screen, and disable one or more operations of the transaction device based on determining that the output is indicative of the obstruction on the display screen.
Patent CA-3140187-A1 (CA)
Inventor: SAVENOK PAVEL
IPC: B65D17/40
Filed: 2020-04-30
Abstract: A re-closeable cap is outfitted upon an upper portion of a beverage can or a series of beverage cans in a multi-pack arrangement for providing a protective barrier atop opened beverage cans. The re-closeable caps include a unibody material construction particularly configured to comprise a cap rim and a cap plate centrally located relative to the cap rim. The cap rim attaches the re-closeable cap to a can rim. The cap plate includes a static portion and at least one dynamic portion all formed from the unibody material construction with complex upper surface landscape and cut lines. The dynamic portions are pivotal relative to the static structure for providing a can-opening access aperture for enabling a user to consume can contents and closing the can-opening access aperture for enabling the user to cover the can opening during contents consumption.
Patent CA-3140976-A1 (CA)
Title: Systems and methods for internal airbed structure
Inventor: OCEGUEDA GALLAGA VICTOR HUGO
IPC: A47C27/08
Filed: 2016-05-09
Abstract: An air mattress comprises an internal structure for helping the air mattress maintain a desired geometric shape when inflated and for preventing shearing of the top and bottom surfaces of the mattress. The internal structure comprises a plurality of connection strips or a mesh web that are attached to a plurality of top surface connection points and bottom surface connection points.
Patent CA-3141275-A1 (CA)
Inventor: DEJOHN MARC
IPC: C12Q1/68
Filed: 2020-06-17
Abstract: The present disclosure provides devices, systems, methods for processing and/or analyzing a biological sample. An analytic device for processing and/or analyzing a biological sample may comprise a moving carriage. The analytic device may be portable. The analytic device may receive instructions for performing an assay from a mobile electronic device external to a housing of the analytic device.
Patent CA-3142684-A1 (CA)
Inventor: AHSAN SYED
IPC: B42D25/20
Filed: 2021-11-21
Abstract: Image of proof of vaccine is printed/transferred on a PVC/plastic card having the size which is resized to standard North American ID card size and is easy to carry anywhere as other ID cards and can be kept with other ID cards in a wallet, purse, pocket or ID card holder etc. Due to this idea, proof of vaccine card image is safe for a long time and due to the property of a PVC/plastic card it is not easily tear able or bendable and is water proof like other ID cards. This idea is cheap and needs no special attention to keep proof of vaccine card separately and saves time to find out as it can be kept with other ID cards.
Patent CA-3151646-A1 (CA)
Inventor: IJASAN OLABODE
IPC: G01N24/08
Filed: 2020-08-14
Abstract: A method for partitioning NMR T1-T2 data may comprise: identifying modes in NMR T1-T2 data from a plurality of samples with a multimodal deconvolution or decomposition with regularized nonlinear inversion; deriving a modal properties vector comprising modal properties for each of the modes; performing a cluster analysis of the modes to identify clusters; assigning a poro-fluid class to the clusters based on one or more of the modal properties of the modes in each of the clusters; and deriving partitioned representations for the clusters based on the cluster analysis.
Patent CA-3152234-A1 (CA)
Inventor: BAIRD DAVID
IPC: B63B17/00
Filed: 2019-10-10
Abstract: Une couverture pour un objet, comme un bateau, pouvant être adaptée à au moins une caractéristique facultative de lobjet, est décrite. La couverture comprend au moins une zone pouvant être élargie pour accueillir la caractéristique facultative de lobjet ou rentrée, si lobjet ne présente pas de caractéristique facultative.
Patent CA-3155223-A1 (CA)
Title: Liquide precurseur de mousse et composition de nettoyage de mousse
Inventor: VASUDEVAN TIRUCHERAI VARAHAN
IPC: A61K8/04
Filed: 2020-10-29
Abstract: L'invention concerne un liquide précurseur de mousse et une composition de nettoyage de mousse qui comprennent un éther de cellulose et un tensioactif. Le liquide précurseur permet d'obtenir une mousse ayant d'excellentes caractéristiques de mousse lors d'une distribution à partir d'un distributeur de mousse à pompe, et le liquide ne s'épaissit pas pour bloquer ou obstruer le distributeur à partir duquel il est distribué. Le liquide précurseur de mousse peut être facilement versé avant la distribution et rend le remplissage et la réutilisation de distributeurs de mousse à pompe très pratiques pour des consommateurs sensibilisés à la nécessité d'utiliser moins de plastique.
Patent CA-3155674-A1 (CA)
Title: Pimobendan formulation and method of use thereof
Inventor: HEPLER DOUGLAS I
IPC: A61K31/55
Filed: 2020-10-23
Abstract: Provided herein are chewable oral formulations including pimobendan for use in mammals to treat cardiac disorders.
Patent CA-3158513-A1 (CA)
Inventor: BUDD HAEBERLEIN SAMANTHA
IPC: A61P25/28
Filed: 2020-10-21
Abstract: Provided are methods for treating Alzheimer's disease in a human subject in need thereof comprising administration of multiple doses of an anti-beta-amyloid antibody (e.g., aducanumab) to the subject.
Patent CA-3158933-A1 (CA)
Title: Three-dimensional scanner and three-dimensional scanning method
Inventor: ZHAO XIAOBO
IPC: G01B11/25
Filed: 2020-10-26
Abstract: The present application discloses a three-dimensional scanner and a three-dimensional scanning method. The three-dimensional scanner includes: an image projection device, configured to project light onto a target object, wherein the light includes predetermined light projected in the form of a color-coded stripe that is formed by coding stripes of at least two colors; and an image acquisition device, configured to acquire light modulated by the target object so as to obtain at least one stripe image in the case where light is projected onto the target object by the image projection device, wherein the obtained stripe image is taken as a coding image to determine respective stripe sequences and as a reconstruction image to perform three-dimensional reconstruction on the target object.
Patent CA-3159974-A1 (CA)
Inventor: SUN ZHIYONG
IPC: C12P7/6427
Filed: 2015-05-21
Abstract: Provided herein are methods for producing one or more polyunsaturated fatty acids. The methods include the steps of providing a microorganism capable of producing polyunsaturated fatty acids, providing a medium comprising a high concentration of one or more carbon sources, low pH, or both, and culturing the microorganism in the medium under sufficient conditions to produce the one or more polyunsaturated fatty acids. Also provided are methods of culturing one or more microorganisms. The methods include culturing the microorganisms in a medium comprising a first amount of one or more carbon sources at a first concentration level, monitoring a carbon source concentration until the carbon source concentration is reduced below the first concentration level, and adding to the medium a second amount of one or more carbon sources to increase the carbon source concentration to a second concentration level.
Patent CA-3161633-A1 (CA)
Inventor: BRANDER CHRISTIAN
IPC: A61K39/12
Filed: 2020-11-12
Abstract: The present invention relates to immunogenic therapies for the treatment or prevention of a human immunodeficiency virus (HIV) infection or a disease associated with an HIV infection.
Patent CA-3161771-A1 (CA)
Inventor: WANG YUE
IPC: G06F16/44
Filed: 2020-11-30
Abstract: A method of distributing location-based message contents over a messaging system and that are displayable on consumer devices present at associated locations. The method comprises, for each message of a set of messages, obtaining a message content and a message location search term, submitting the message location search term to a web mapping service so that a service application programming interface (API) searches with the message location search term, and receiving a result list including a plurality of message locations corresponding to the message. The method further comprises adding the message content and the plurality of message locations to a message distribution database or set of linked databases that is or are searchable by location. This facilitates the sending of relevant message location(s) to the consumer devices.
Patent CA-3162635-A1 (CA)
Inventor: Edelin John Bradley
IPC: F02M35/08
Filed: 2020-11-23
Abstract: Système de limitation de siloxane (30) destiné à un système de machine (10) ayant un moteur à combustion interne (25) comprenant un piège à siloxane (32) ayant une pluralité de cartouches adsorbantes (36) en parallèle les unes aux autres, un pré-épurateur d'air (38) en communication fluidique avec une entrée de boîtier de piège (46), et une soufflante (40) structurée pour souffler de l'air d'admission vers le piège à siloxane (32) afin de compenser une perte de charge à travers le piège à siloxane (32). Un capteur de performance de piège (66) du système de limitation de siloxane (30) est structuré pour surveiller une pression d'échappement afin d'indiquer une dégradation de performance du système de limitation de siloxane (30) et d'activer une alerte perceptible par un opérateur.
Patent CA-3163088-A1 (CA)
Title: Platelet diagnostic imaging agents
Inventor: SHEIK DANIEL ALLEN
IPC: A61K49/08
Filed: 2020-11-25
Abstract: Provided herein are MRI agent-loaded platelets, methods of preparing MRI agent-loaded platelets, and methods of using MRI agent-loaded platelets. In some embodiments, methods of loading MRI agents into platelets include contacting platelets with an MRI agent, a cell penetrating peptide, and a loading buffer that can include a salt, a base, a loading agent, and optionally at least one organic solvent.
Patent CA-3163319-A1 (CA)
Inventor: ABRAHAM JIM
IPC: C12Q1/6809
Filed: 2020-06-03
Abstract: Un profilage moléculaire complet fournit une richesse de données concernant l'état moléculaire d'échantillons de patient. De telles données peuvent être comparées à une réponse de patient à des traitements pour identifier des signatures de biomarqueurs qui prédisent une réponse ou une non-réponse à de tels traitements. Cette approche a été appliquée pour identifier des signatures de biomarqueurs qui sont fortement corrélées à la réponse des patients soumis à une chimiothérapie à base de platine. L'invention concerne des structures de données, un traitement de données et des modèles d'apprentissage automatique pour prédire l'efficacité d'un traitement pour une maladie ou un trouble d'un sujet ayant un ensemble particulier de biomarqueurs, ainsi qu'un exemple d'application d'un tel modèle à un traitement de précision, par exemple, des procédés de sélection d'un traitement sur la base d'un profil moléculaire, par exemple, un traitement comprenant une thérapie à base de platine.
Patent CA-3163940-A1 (CA)
Inventor: LENNON ERIC E
IPC: D01D5/098
Filed: 2020-01-31
Abstract: L'invention concerne un procédé de fabrication de bandes non tissées consistant à utiliser une filière comprenant un motif de conduits formant une région d'extrusion ; diriger uniquement un premier courant de polymère de propylène fondu dans une région adjacente au premier côté de la filière, diriger uniquement un second courant de polymère de propylène fondu dans une région distale par rapport au premier côté de la filière, extruder uniquement le premier flux de polymère de propylène à travers les ouvertures de sortie dans une première zone où l'ouverture de sortie comprend des orifices de sortie dans la première zone ayant une première densité ; extruder uniquement le second flux de polymère de propylène à travers les ouvertures de sortie d'une seconde zone où l'ouverture de sortie comprend des orifices de sortie dans la seconde zone ayant une seconde densité inférieure à la première densité ; et la seconde zone étant distale par rapport au premier côté et la première zone étant entre la seconde zone et le premier côté.
Patent CA-3164812-A1 (CA)
Title: Systeme de transport de charges et/ou de personnes en hauteur
Inventor: MAZZALAI PAOLO
IPC: B61B12/00
Filed: 2020-12-14
Abstract: Le système (7) destiné au transport de charges et/ou de personnes en hauteur comprend au moins une voiture (1) délimitant au moins une cabine (2) pour le transport de charges et/ou de personnes, et comprend : - des moyens de transport de câble (4) de la voiture (1) aptes à déplacer cette dernière suspendue en hauteur ; des moyens de déplacement (6) de la voiture (1) sur le sol.
Patent CA-3168362-A1 (CA)
Title: Adjustable drilling rig
Inventor: KING CHRISTOPHER TYLER
IPC: E21B15/00
Filed: 2022-07-20
Abstract: An adjustable drilling rig is provided for drilling and installation of foundational micropile matrices in difficult to access locations. A platform and separately adjustable legs are provided to level the platform. Arms and a crossbar mount to the legs, and each includes a bushing slidably mounted and moveable there along. A mast is slidably attached to the crossbar bushing through a mounting plate. The mast carries a drill head to which a drill will be attached. Various adjusters are mounted to bushings, mounting plate and other components of the adjustable drilling rig and are independently and selectively activated to adjust the drill head translationally along the X-, Y-and Z-axes and rotationally about the X- and Y-axes to achieve five degrees of freedom in five planes. The entire adjustable drilling rig is provided in two frames for easy transport to remote work sites and may be assembled without complex tools.
Patent CA-3168493-A1 (CA)
Inventor: ROUTY BERTRAND
IPC: A61P37/02
Filed: 2021-02-19
Abstract: Methods and uses for enhancing or restoring the antitumor response, such as the antitumor immune mediated by immune checkpoint inhibitors, in cancer patients, are described. These methods are based on the administration of castalagin or analogs thereof, and are particularly useful for the treatment of tumors resistant to immunotherapy such as immune checkpoint inhibitor therapy. The castalagin or analog thereof may be administered in any suitable form, for example in a crude plant or fruit extract such as a Myrciaria dubia extract, or in a pharmaceutical composition.
Patent CA-3168495-A1 (CA)
Inventor: BLAGG JULIAN
IPC: C07D209/44
Filed: 2021-01-20
Abstract: The present invention relates to novel probe compounds of formulae I and II defined herein. The present invention also relates to methods of synthesising these novel probe compounds and to their use in assays and screens for determining the binding of a test molecule to the ATP-binding site of a target protein, such as, for example, the Mismatch Repair (MMR) component proteins PMS2 and MLH1, or for determining the location and/or quantity of such target proteins in a biological sample.
Patent CA-3170753-A1 (CA)
Title: Methods for call and message handling
Inventor: WANG ZHENKUN
IPC: H04M1/663
Filed: 2022-08-19
Abstract: A call handling method is provided. The call handling method, comprising receiving a notification of a call with a caller id number; searching for a first contact tuple corresponding to the caller id number in a filter book; determining whether a category of the first contact tuple is denoted as normal when the contact tuple is found; and prompting a user to answer the call when the category of the contact tuple is not denoted as normal.
Patent CA-3171477-A1 (CA)
Inventor: SNYDER TODD
IPC: B61L27/00
Filed: 2021-03-19
Abstract: In one aspect, a mobile railway asset monitoring apparatus is provided that includes a sensor configured to produce a signal indicative of a rotation of a wheelset of a mobile railway asset. The apparatus further includes a processor to receive data corresponding to a ground speed of the mobile railway asset. The processor is operably coupled to the sensor, the processor configured to estimate a running dimension of the wheelset based at least in part on the rotation of the wheelset and the ground speed of the mobile railway asset. The processor is configured to determine at least one parameter of the mobile railway asset based at least in part on the running dimension of the wheelset.
Patent CA-3173884-A1 (CA)
Inventor: WAGER GEBHARD CHARLES
IPC: F16K15/20
Filed: 2021-04-01
Abstract: La présente invention concerne une soupape en ligne qui comprend un piston en ligne ayant des surfaces de came à dents inclinées montées pour un coulissement non rotatif le long d'un conduit, et un piston plongeur à orifices en ligne ayant des surfaces de came à dents inclinées montées pour coulisser et tourner le long du conduit. Les surfaces de came de dent inclinées sur le piston et le piston plongeur sont sollicités élastiquement dans une relation de face à face opposée de sorte à venir en prise de manière coulissante en rotation les unes sur les autres. Ceci indexe de manière sélective le piston dans des positions ouverte et fermée de soupape. Le piston plongeur est entraîné contre la sollicitation élastique de rappel du piston par une impulsion de pression de fluide modulée à partir de la conduite de fluide fixée à la soupape. Dans la position ouverte de la soupape, un orifice dans le piston fait passer le fluide à travers le piston et le piston plongeur et le long de la conduite de fluide. Dans la position fermée de la soupape, l'orifice est fermé et le piston ferme l'écoulement de fluide à travers le piston et le piston plongeur.
Patent CA-3174003-A1 (CA)
Inventor: KENNEDY THOMAS L
IPC: E02F3/36
Filed: 2022-09-13
Abstract: A loader for a work vehicle includes a loader arm, a mast section rotatably connected to the loader arm, an implement removably attached to the loader arm, a first actuator connected between the loader arm and the mast, a second actuator connected between the loader arm and the implement, and a first roller apparatus having a use position and a storage position. The first roller apparatus is positioned nearer a ground surface in the use position than in the storage position. The first roller apparatus is in contact with the ground surface in the use position and spaced apart from the ground surface in the storage position.
Patent CA-3176310-A1 (CA)
Inventor: LAURENT HUGO
IPC: B29D35/14
Filed: 2021-04-26
Abstract: The invention relates to a device comprising: a first layer (11) made of a thermoformable material which is non-elastically deformable in a thermoforming temperature range, a second layer (1) made of a viscoelastic material which is elastically deformable in a temperature range including a working temperature range of the device and the thermoforming temperature range, and in which: the working temperature range is lower than the thermoforming temperature range, the first layer is bonded to the second layer by a contact surface between the first layer and the second layer, the thermoformable material is elastically deformable and more rigid than the viscoelastic material in the working temperature range, and the thermoformable material is less rigid than the viscoelastic material in the thermoforming temperature range.