baber/WOPTO huggingface dataset:
Patent WO-2021076629-A1 (WO)
Title: Procédé de préparation de (1r, 4r, 5s)-4-(2-chloroéthyl)-1-((s)-((s)-cyclohex-2-en-1-yl)(hydroxy) méthyl)-5-méthyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione(salinosporamide a ; marizomib)
Inventor: YONG KELVIN
IPC: C12P17/16
Filed: 2020-10-14
Abstract: La présente invention concerne un procédé de synthèse de (1R, 4R, 5S)-4-(2- chloroéthyl)-1-((S)-((S)-cyclohex-2-en-1-yl)(hydroxy)méthyl)-5-méthyl-6-oxa-2- azabicyclo[3.2.0]heptane-3,7-dione ; composé 1 (salinosporamide A, marizomib) : (Composé 1).
Patent WO-2021076953-A1 (WO)
Inventor: OBRAD FRANK
IPC: F17C13/00
Filed: 2020-10-16
Abstract: Method, system, apparatus, and/or device for tipping or pouring a dewar into another receptacle. The dewar tipping system includes a first dewar. The first dewar is configured to store a liquid or gas. The dewar tipping system includes a dewar tipper with a cradle. The cradle is configured to capture the first dewar. The dewar tipper includes a counter balance assembly that is configured to tip or angle the cradle to pour a liquid or gas out of the first dewar. The dewar tipper includes a handle. The handle is configured to activate the counter balance assembly when in an engaged position. The dewar tipping system includes one of a second dewar or a catch basin. The one of the second dewar or the catch basin receives the liquid or gas when the first dewar is angled or inverted.
Patent WO-2021077051-A1 (WO)
Title: Improved lamp constructs comprising cancer antigens
Inventor: HEILAND TERI
IPC: A61K39/00
Filed: 2020-10-17
Abstract: The present invention provides improved LAMP Constructs comprising specific fragments of the LAMP lumenal domain to deliver cancer antigens to immune cells for enhanced processing. These LAMP Constructs can be used for the treatment of disease and in particular hyperproliferative disorders and/or cancer. The improved LAMP Constructs allow for presentation of properly configured three dimensional epitopes for production of an immune response when administered to a subject. The improved LAMP Constructs can be multivalent molecules, and/or can be provided as part of a multivalent vaccine containing two or more LAMP Constructs. The improved LAMP Constructs as described herein can also be used to generate antibodies when administered to a non-human vertebrate.
Patent WO-2021091876-A1 (WO)
Inventor: ZHOU YAN
IPC: H04L5/00
Filed: 2020-11-03
Abstract: Certain aspects of the present disclosure relate to methods and apparatus for applying a common power saving behavior across multiple sets of frequency resources (e.g., component carriers (CCs) and/or bandwidth parts (BWPs)). A method that may be performed by a user equipment (UE) includes obtaining signaling, from a network entity, indicating a common power saving behavior and applying the common power saving behavior on multiple sets of frequency resources.
Patent WO-2021096816-A1 (WO)
Title: Subcutaneous device for monitoring and/or providing therapies
Inventor: MANICKA YATHEENDHAR
IPC: A61N1/365
Filed: 2020-11-09
Abstract: A subcutaneously implantable device includes a clip that is configured to anchor the subcutaneously implantable device to a muscle, a bone, and/or a first tissue, and a first prong with a proximal end attached to the clip and a distal end extending away from the clip that is configured to contact an organ, a nerve, and/or a second tissue. A first electrode on the first prong is configured to contact the organ, the nerve, and/or the second tissue. A wire conductively connected to the first electrode is configured to be connected to an external device that is positioned outside of a patient's body to electrically connect the subcutaneously implantable device to the external device.
Patent WO-2021097029-A1 (WO)
Title: Hybrid mechanically lined pipe methods and apparatus
Inventor: BOISNE MATHIEU
IPC: F16L57/02
Filed: 2020-11-12
Abstract: Aspects of the present disclosure relates to methods of making a hybrid mechanically lined pipe, and apparatus thereof, such as lined pipe used for reeled pipe operations. In one implementation, a method of making a lined pipe for reeled pipe operations includes determining a minimum weld overlay length for a first pipe joint, and providing the first pipe joint. The first pipe joint includes a first end opposite of a second end, a central opening, and an inner surface, The method includes mechanically lining the inner surface of the first pipe joint with a first section of alloy. The method also includes weld overlaying a second section of alloy and a third section of alloy in the central opening and on both sides of the first section of alloy over the minimum weld overlay length to prevent excessive deformation of the mechanically bonded section during reeling operations.
Patent WO-2021097322-A1 (WO)
Title: Beam failure report response
Inventor: ZHOU YAN
IPC: H04L1/18
Filed: 2020-11-13
Abstract: Aspects relate to mechanisms for wireless communication devices to report a beam failure. A UE detects a beam failure with a cell. The UE transmits a beam failure recovery request including an indication of a candidate beam to a base station in response to detecting the beam failure. The base station transmits a beam failure recovery response to the UE indicating whether the beam failure recovery request is received. The UE applies the candidate beam indicated in the beam failure recovery request for a downlink channel following a predetermined number of symbols after an end of the beam failure recovery response. The UE transmits an acknowledgment (ACK) message to the base station when the beam failure recovery response is decoded. The UE applies the candidate beam indicated in the beam failure recovery request for a downlink channel following a predetermined number of symbols after an end of the ACK message.
Patent WO-2022132126-A1 (WO)
Title: Régulation de température d'un panneau audio
Inventor: JOSE JENNIS
IPC: H04R29/00
Filed: 2020-12-14
Abstract: Un dispositif mobile comprend un haut-parleur audio à panneau comprenant un panneau d'affichage et un actionneur couplé au panneau d'affichage. Le dispositif mobile comprend un capteur de température conçu pour détecter une température du panneau d'affichage, et un module de commande électronique en communication avec l'actionneur et le capteur de température. Le module de commande électronique est programmé pour effectuer des opérations comprenant : l'obtention, auprès du capteur de température, de données indiquant une température du panneau d'affichage; et sur la base des données indiquant la température du panneau d'affichage, l'ajustement d'un signal de puissance fourni à l'actionneur pour exciter le haut-parleur audio à panneau. Le signal de puissance peut être ajusté par sélection, sur la base des données indiquant la température du panneau d'affichage, d'une température cible du panneau d'affichage; mise en correspondance de la température cible avec un niveau de puissance cible; et changement du signal de puissance fourni à l'actionneur pour le niveau de puissance cible.
Patent WO-2021138111-A1 (WO)
Title: Automatic camera washer deactivation
Inventor: LETIZIO MATTHEW E
IPC: B60S1/48
Filed: 2020-12-21
Abstract: A vehicle camera washing system includes a controller configured to control a pump and valve according to a selected mode of operation and a detected blockage of the lens. The selected mode of operation tailors operation of the camera washing system to current vehicle operating conditions to conserve washing fluid.
Patent WO-2021138488-A1 (WO)
Title: Dvb-s2 downlink acm algorithm enhancement to improve data throughput
Inventor: FAN ZENGQUAN
IPC: H04L29/00
Filed: 2020-12-30
Abstract: An apparatus for determining a set of transmit parameters capable of improving and/or optimizing data throughput to a destination device. The apparatus includes an input circuit that receives a signal containing a plurality of data blocks for use by a plurality of devices. At least one of the data blocks is associated with the apparatus and encoded using a first set of transmit parameters. A transmit parameter processor determines a signal to noise ratio value for the received signal and a block error rate value for the at least one data block and at least one other data block encoded using a different set of transmit parameters. A processor generates a request for encoding subsequent data blocks destined to the apparatus using a second set of transmit parameters. A method and system are also disclosed.
Patent WO-2021026553-A1 (WO)
Title: Plateforme de messagerie de distribution de messages en temps réel
Inventor: RENJITH RISHI
IPC: H04L29/08
Filed: 2020-07-28
Abstract: La présente invention concerne une diffusion en continu de messages en temps réel dans le temps vers des applications de client conformément à des abonnements de requête qui correspondent à un contenu à partir d'un grand flux de messages échangés sur une plateforme de messagerie d'une manière qui augmente la vitesse de distribution de messages, qui commande efficacement la gestion de ressources informatiques pour gérer la fluctuation du nombre d'abonnements de requête actifs, et/ou qui augmente la sécurité de mise en correspondance des abonnements de requête avec des messages générés depuis la perspective des auteurs tout en délivrant ces messages en temps réel depuis la perspective des utilisateurs qui ont initié les abonnements de requête.
Patent WO-2021162847-A1 (WO)
Title: Transfer assembly and system for aquaculture
Inventor: HOLM THUE
IPC: A01K63/04
Filed: 2021-01-25
Abstract: A system for transferring marine life within an aquaculture facility including a plurality of segregated storage facilities each containing water for marine life, maintained within a predetermined temperature range and supported at independent ground levels. The storage facilities are successively disposed and structured to contain marine life at different stages of growth. A transfer assembly includes a path of fluid flow interconnecting successive ones of said plurality of storage facilities in fluid communication with one another, wherein at least a majority of a length of said path of fluid flow is disposed beneath the independent ground levels at a predetermined depth, which is sufficient to facilitate maintenance of the path of fluid flow within the predetermined temperature range, via geothermal cooling.
Patent WO-2021154888-A1 (WO)
Title: Non-naturally occurring vesicles comprising a chimeric vesicle localization moiety, methods of making and uses thereof
Inventor: GAIGE TERRY
IPC: G01N33/50
Filed: 2021-01-27
Abstract: Disclosed herein are non-naturally occulting vesicle comprising a chimeric vesicle localization moiety comprising a surtace-and-transmembrane domain of a first vesicle localization moiety and a cytosolic domain of a second vesicle localization moiety, the method of making said vesicle and uses thereof.
Patent WO-2021155252-A1 (WO)
Title: Method for quantitating nucleic acid library
Inventor: FEKETE RICHARD
IPC: C12N15/10
Filed: 2021-01-29
Abstract: A method for quantitating a plurality of nucleic acid molecules is provided. The method includes contacting a plurality of detectably-labeled probes and a plurality of extension primers with the plurality of nucleic acid molecules, each detectably-labeled probe including a first labeled nucleic acid domain having a first label; producing an extension product of each of the plurality of target nucleic acid fragments by extending a respective one of the plurality of extension primers with a polymerase; hydrolyzing each of the plurality of detectably-labeled probes hybridized to the respective one of the target nucleic acid fragments during extending the respective one of the plurality of extension primers with the polymerase; detecting a first signal produced as a result of hydrolyzing the plurality of detectably-labeled probes; and calculating a number of the plurality of target nucleic acid fragments based on signals detected upon a single cycle of extension reactions.
Patent WO-2021158613-A1 (WO)
Title: Learning singing from speech
Inventor: YU CHENGZHU
IPC: G10L15/02
Filed: 2021-02-03
Abstract: A method, computer program, and computer system is provided for converting a singing voice of a first person associated with a first speaker to a singing voice of a second person using a speaking voice of the second person associated with a second speaker. A context associated with one or more phonemes corresponding to the singing voice of a first person is encoded, and the one or more phonemes are aligned to one or more target acoustic frames based on the encoded context. One or more mel-spectrogram features are recursively generated from the aligned phonemes, the target acoustic frames, and a sample of the speaking voice of the second person. A sample corresponding to the singing voice of a first person is converted to a sample corresponding to the second singing voice using the generated mel-spectrogram features.
Patent WO-2021163137-A1 (WO)
Title: Computational architecture for active noise reduction device
Inventor: CARRERAS RICARDO FEDERICO
IPC: G10K11/178
Filed: 2021-02-10
Abstract: A computational architecture for a personal active noise reduction (ANR) device (10). The device includes a communication interface (12) that receives an audio stream (32), a driver, a microphone system (28) and an ANR processing platform (14). The platform includes a first DSP (20) configured to: receive the audio stream (32) and signals from the microphone system (28), perform ANR on the audio stream (32) according to a set of parameters in the first DSP (20), and output a processed audio stream (34). The platform includes a second DSP (22) configured to: generate state data in response to an analysis of the source audio stream (32), signals from the microphone system (28), and the processed audio stream (34); and alter the operational parameters on the first DSP (20). The platform includes a general purpose processor (24) configured to: communicate control signals (40) with the communication interface (12), process state data from the second DSP (22), and alter the parameters on the first DSP (20).
Patent WO-2021188234-A1 (WO)
Title: Method of treating an individual with a health condition with fecal microbiota transplant
Inventor: HAZAN SABINE
IPC: C12Q1/6869
Filed: 2021-02-11
Abstract: A method of treating an individual with a health condition comprising the steps of: a) screening the individual to determine a level of severity of the health condition; b) acquiring a fecal sample from the individual; c) processing the fecal sample; d) sequencing the fecal sample to determine the individuals microbiome; e) analyzing the sequenced fecal sample, wherein the step of analyzing the sequenced fecal sample comprises: i) comparing the individual's microbiome to the microbiome of a parent of individual; ii) comparing the individual's microbiome to the microbiome of a sibling of the individual; iii) comparing the individual's microbiome to the microbiome of another individual with same health condition; and iv) comparing the individual's microbiome with a health condition to the microbiome of the individual before they acquired the health condition; f) administering vancomycin to the individual; g) performing the fecal microbiota transplant; and h) monitoring the individual.
Patent WO-2021183947-A1 (WO)
Title: MOLECULES THAT BIND TO SARS-CoV-2
Inventor: DIMITROV DIMITER
IPC: A61K39/00
Filed: 2021-03-12
Abstract: This document provides methods and materials involved in binding a binder (e.g., an antibody, antigen binding fragment, and/or antibody domain) to a SARS-CoV-2 antigen. For example, binders (e.g., antibodies, antigen binding fragments, and antibody domains) that bind to a SARS-CoV-2 polypeptide and methods and materials for using one or more such binding molecules to treat a mammal (e.g., a human) having COVID-19 (or a viral infection caused by SARS-CoV-2) are provided.
Patent WO-2021211607-A1 (WO)
Title: Anti-free-flow valve assembly with flow bypass
Inventor: MIJERS JAN WILLEM
IPC: A61M39/22
Filed: 2021-04-13
Abstract: An enteral feeding valve assembly includes a housing assembly that is fluidly coupled with an upstream line and a downstream line. A diverging conduit inwardly extends from an inlet and a primary conduit inwardly extends from an outlet of the housing. The diverging conduit splits into a bypass conduit and a flow-through conduit. The flow-through conduit is fluidly coupled with the primary conduit by a check valve. A plunger valve includes one or more plunger conduits and moves in a first direction to fluidly couple the inlet with the primary conduit and the outlet via the bypass conduit and the one or more plunger conduits. The plunger valve moves in a second direction to de-couple the inlet from the primary conduit and the outlet via the bypass conduit and the one or more plunger conduits. The flow-through conduit directs the fluid to the outlet through the check valve.
Patent WO-2021222189-A1 (WO)
Title: Method for increasing serum adiponectin for treatment and reduction of the risk of cardiovascular, vascular, and related diseases
Inventor: CATARINO ROGER
IPC: A61K35/74
Filed: 2021-04-27
Abstract: The invention provides methods for reducing the percentage of body fat, increasing the level of adiponectin, and/or treating or reducing the risk of cardiovascular disease (CVD) and coronary heart disease (CHD). Such methods include administering to an animal or human sufficient levels of a compound comprising a tri blend of HPMC (K15, K100, and K200) and myristic fatty acid.
Patent WO-2021222683-A1 (WO)
Inventor: EPSTEIN SCOTT R
IPC: H04N21/433
Filed: 2021-04-30
Abstract: A synchronization control device configured to synchronize media play between at least two remote devices is disclosed. The synchronization control device includes: an input for receiving data indicating a point in a play of media content on a first remote media play device; and a synchronization controller module configured to align the point of play of media content on a first remote media play device with a point of play of the media content at a second remote media play device; and delivering commands to the first remote media play device and the second remote media display device, wherein the commands control the first remote media play device and the second remote media play device to substantially synchronize the play of the media content in the first remote media play device and the second remote media play device.
Patent WO-2021236521-A1 (WO)
Title: Managing computer resources for clinical applications
Inventor: DRAPKIN EVGENY
IPC: G16H70/00
Filed: 2021-05-17
Abstract: Techniques regarding the management of computational resources based on clinical priority associated with one or more computing tasks are provided. For example, one or more embodiments described herein can regard a system comprising a memory that can store computer-executable components. The system can also comprise a processor, operably coupled to the memory, that executes the computer-executable components stored in the memory. The computer-executable components can include a prioritization component that can prioritize computer applications based on a clinical priority of tasks performed by the computer applications. The clinical priority can characterize a time sensitivity of the tasks. The computer-executable components can also include a resource pool component that can divide computational resources across a plurality of resource pools and can assign the computer applications to the plurality of resource pools based on the clinical priority.
Patent WO-2022055579-A1 (WO)
Title: Rotatably coupled touch screen displays
Inventor: PUNDAK GILAD
IPC: G06F3/044
Filed: 2021-06-01
Abstract: Examples are disclosed relating to computing devices and methods for performing capacitive touch detection in rotatably coupled displays. In one example, a method comprises: in a first display, providing a first signal at a first frequency to a first drive electrode in a first frequency region abutting a first non-coupled side opposite to a first coupled side. Other signals at other frequencies are provided to other drive electrodes in other frequency regions. In a second display, a second signal at the first frequency is provided to a second drive electrode located in a different first frequency region abutting a second coupled side opposite to a second non-coupled side. The other frequency regions of the first display are positioned between the first frequency region and the different first frequency region, thereby spatially separating the first frequency region from the different first frequency region.
Patent WO-2021247877-A1 (WO)
Inventor: SHASHANKA JAIN BELUR SHANTHAKUMAR
IPC: A61M1/28
Filed: 2021-06-03
Abstract: A peritoneal dialysis system includes: a bellows; a common inlet/outlet fluid receptacle in fluid communication with the bellows; a plurality of fluid lines in fluid communication with the common inlet/outlet line; a linear actuator positioned and arranged to expand and compress the bellows; a plurality of valves positioned and arranged to allow or occlude flow through the plurality of fluid lines to or from the bellows; and a control unit configured to control the linear actuator and the plurality of valves.
Patent WO-2021252769-A1 (WO)
Title: Ph-responsive lipidoid nanoparticles for intracellular mrna delivery
Inventor: XU QIAOBING
IPC: A61K31/519
Filed: 2021-06-10
Abstract: Disclosed are lipidoid compounds as well as lipidoid nanoparticles comprising such compounds.
Patent WO-2022006097-A1 (WO)
Title: Adjustable resistance weight sled with bias correction, wheel skid control, and omni-directional motion
Inventor: BAZARGAN SAHM
IPC: B62M29/00
Filed: 2021-06-29
Abstract: A weight sled that allows both linear and non-linear movements such that resistance training can be performed in the frontal, sagittal, and combined frontal/sagittal planes, and which allows easy movement for transportation, storage, and retrieval from storage. The weight sled uses one or more swiveling, pivoting, or omni-directional wheels that allow all or a portion of the sled to be moved laterally. The addition of wheel configurations allowing of lateral movement of all of, or a portion of, the weight sled greatly expands the utility of weight sleds because movement in any direction can be trained, whether in the sagittal body plane (forward/backward movements), the frontal body plane (lateral movements), or a combination of the two. Additionally, the plurality of wheel configurations allows for a variety of storage arrangements.
Patent WO-2022103450-A1 (WO)
Title: Complexes de cyclodextrine de lactone macrocycliques solubles dans l'eau
Inventor: FARBER MICHAEL
IPC: A61K47/26
Filed: 2021-07-09
Abstract: Solution d'ivermectine injectable administrable en toute sécurité aux êtres humains et aux animaux utilisée dans la technologie divulguée. Un complexe de cyclodextrine de lactone macrocyclique qui est complètement soluble ou dissous dans de l'eau dans un rapport d'au moins 5 ou 10 mg de lactone macrocyclique à 1 ml d'eau. Le complexe de cyclodextrine de lactone macrocyclique est non toxique, sans utiliser de solvants organiques, et dans des modes de réalisation, formé par l'ajout d'un tensioactif au complexe de lactone macrocyclique à l'eau. Le complexe de cyclodextrine de lactone macrocyclique est l'ivermectine ou un dérivé d'ivermectine dans certains modes de réalisation. Le complexe de cyclodextrine est du 2-hydroxypropyl-beta-cyclodextrine dans certains modes de réalisation de la technologie divulguée. Le tensioactif peut être du polysorbate 80 et est dans un rapport de 0,01 % à 25 %, en poids, à ladite eau. Les complexes solubles dans l'eau peuvent être ajoutés à l'eau. Les complexes solubles dans l'eau peuvent avoir au moins l'un d'un complexe anti-parasitaire, antiviral et anticancéreux.