baber/WOPTO huggingface dataset:
Patent AU-2019204938-A1 (AU)
Title: Mdm2 inhibitors and combinations thereof
Inventor: HALILOVIC ENSAR
IPC: A61K31/519
Filed: 2019-07-09
Abstract: C:\Interwo n\NRPortbl\DCC\DAR\19042665_I.docx-8/07/2019 The present disclosure relates to a pharmaceutical combination comprising (a) an Mdm2 inhibitor and (b)(i) a MEK inhibitor and/or (b)(ii) Bc2 inhibitor, particularly for use in the treatment of a cancer. This disclosure also relates to uses of such combination for preparation of a medicament for the treatment of a cancer; methods of treating a cancer in a subject in need thereof comprising administering to said subject ajointly therapeutically effective amount of said combination; pharmaceutical compositions comprising such combination and commercial packages thereto. WO 2017/037579 PCT/1B2016/055050 HCT-116xenograft 700 Treatment 600 G2AB",P-263 * jCOMPO L ND A ?500 ad9,:+ABT-263 400 at d9S: -AT-263 G6 COPCEU$4D A-trnmt~nrvt±ABT-263 2 00 -19 Li ooJ 0 2 4 6, 8 10 12 14 16 18 20 ±AB124,3to G3,0G4.G5 Days of treatment (U)
Patent AU-2019206127-A1 (AU)
Title: Electronic lock having usage and wear leveling of a touch surface through randomized code entry
Inventor: LOVETT MATTHEW
IPC: E05B47/00
Filed: 2019-07-19
Abstract: ELECTRONIC LOCK HAVING USAGE AND WEAR LEVELING OF A TOUCH SURFACE THROUGH RANDOMIZED CODE ENTRY An electronic lock that requires the user complete a wear leveling action prior to entering in the passcode. The wear leveling action causes the user to touch one or more portions of the touch interface that may not be associated with the passcode to distribute wear of the touch interface. These area(s) of the touch interface selected for the wear leveling actions could be determined based on a pseudorandom number generator and/or by tracking usage of the touch interface to identify less used areas.
Patent AU-2019214534-A1 (AU)
Title: Lenses with optical markings
Inventor: GENGLER RÉGIS Y N R
IPC: A61F9/00
Filed: 2019-02-01
Abstract: A lens including a posterior surface, an anterior surface, and at least one identification marking on the lens. The at least one identification marking exhibits a first degree of visibility in an ambient lighting condition and a second degree of visibility greater than the first degree of visibility in a lighting condition different than the ambient lighting condition.
Patent AU-2019225468-A1 (AU)
Title: Submarine cable control by use of variable specific gravity and diameter cables and/or external forces for cables used with cable-propelled marine vessels
Inventor: ASKGAARD IVAN
IPC: B63B21/56
Filed: 2019-02-07
Abstract: Cables for propulsion and/or guidance of cable ferries are disclosed which permit their use on longer ferry routes. One embodiment provides the use of cables for propulsion and/or guidance of cable ferries where the unit weight, density, specific gravity and/or diameter of the cable is variable over the length of the cable. According to one embodiment, heavier or denser cable is used adjacent to the terminals, while lighter or less dense cable is used for a middle section. Where sections have positive buoyancy, the cable may be tethered to one or more anchors. Where sections have negative buoyancy, the cable may be tethered to one or more floats.
Patent AU-2019234488-A1 (AU)
Title: Techniques for optimizing communication protocols
Inventor: CHEN YUEXI
IPC: G06Q20/20
Filed: 2019-03-11
Abstract: A thin client may be utilized to facilitate data exchanges between two devices (e.g., a remote computer and a portable device). In some embodiments, the two devices may utilize differing communications protocols. The thin client may further be configured with a rules engine that determines one or more actions to be performed in response to one or more stimuli. The thin client may manage the processing flow between the two devices according to one or more predefined rules that are interpretable by the rules engine. The rules may be pushed to the thin client via any suitable device enabling the functionality of the thin client to be configured and/or modified without having to update the hardware and/or software of the thin client.
Patent AU-2019246791-A1 (AU)
Title: Invertible coupler ring for railway axle bearing assemblies
Inventor: ANDERSON JOSH
IPC: B61F15/20
Filed: 2019-10-09
Abstract: A coupler is for selectively coupling a first bearing ring with a first backing ring or a second bearing ring with a second backing ring and includes a flexible annular body disposeable simultaneously within the first bearing ring and first backing ring or within the second bearing 5 ring and second backing ring. A first bearing projection and a first backing ring projection extend radially from a first circumferential surface and are axially spaced apart and a second bearing projection and a second backing ring projection extend radially from a second circumferential surface and are axially spaced apart. The body is invertible between a first orientation in which the first bearing ring and backing ring projections are disposeable within the 0 first bearing and backing ring openings and a second orientation in which the second bearing ring and backing ring projections are disposeable within the second bearing and backing ring openings. IOf OD' c4C
Patent AU-2019255225-A1 (AU)
Title: Wicks for candles and other lighting devices
Inventor: DECKER DAYNA M
IPC: C11C5/00
Filed: 2019-04-16
Abstract: A wick includes a sheet of wick material. The wick has a height dimension, a width dimension, and a thickness dimension. The height dimension and the width dimension are greater than the thickness dimension. The height dimension extends from the top of the wick to the bottom of the wick as the wick is oriented when provided in a candle. The width dimension and the thickness dimension are perpendicular to the height dimension. The sheet of wick material may be dyed, provided with a visible pattern and/or provided with a plurality of cut-out portions.
Patent AU-2019277154-A1 (AU)
Title: Bio-based medicines and methods of increasing patient compliance
Inventor: SUDOLSKY DAVID
IPC: A61K31/495
Filed: 2019-05-28
Abstract: Medicines that are used to treat diseases are conventionally made from starting materials that are derived from fossil fuels and therefore contain essentially no 14C. In the present invention, medicines can be partially or fully derived from biological sources and therefore contain about one part per trillion (ppt) 14C. These compounds have been discovered as superior for the treatment of disease because they have surprisingly been found to substantially increase patient compliance. Compounds and methods of using partially or fully bio-based pharmaceutically active compounds to track metabolites are also disclosed.
Patent AU-2019284084-A1 (AU)
Title: Universal self-limiting electrosurgical return electrode
Inventor: EHNINGER MICHAEL D
IPC: A61B18/16
Filed: 2019-12-24
Abstract: A self-limiting electrosurgical return electrode for use with electrosurgical procedures is disclosed. The return electrode includes a conductive element and pads disposed on opposing sides of the conductive element. The conductive element, optionally in combination with the pads, is configured to limit the density of electrical current that passes from a patient to the return electrode. The conductive element and the pads can cooperate to define two separate working surfaces on opposing sides of the return electrode. The return electrode can also be safely used with patients of substantially any size and without requiring adjustments to the power settings of an electrosurgical generator. Figure 5 WO 2015/100438 PCT/US2014/072426 I'136C FIG.4'
Patent AU-2019284269-A1 (AU)
Title: Loading structure with tether guide for unmanned aerial vehicle
Inventor: SCHAMLZRIED JIM
IPC: B64F1/32
Filed: 2019-06-06
Abstract: A payload loading system is disclosed. The payload loading system includes a UAV and a loading structure. A retractable tether is coupled to a payload coupling apparatus at a distal end and the UAV at a proximate end. A payload is loaded to the UAV by coupling the payload to the payload coupling apparatus. The loading structure of the payload loading system includes a landing platform and a tether guide. The tether guide is coupled to the landing platform and directs the tether as the UAV approaches and travels across at least a portion of the landing platform such that the payload coupling apparatus arrives at a target location. The payload is loaded to the payload coupling apparatus while the payload coupling apparatus is within the target location.
Patent AU-2019313158-A1 (AU)
Title: Concrete reinforcement assembly
Inventor: SILVA JOHN
IPC: B21F27/12
Filed: 2019-07-26
Abstract: There is proposed a reinforced concrete structure comprising a reinforcement assembly embedded therein, the reinforcement assembly including first and second lengths of chain, wherein the first and second lengths of chain being pretensionable prior to forming the concrete structure. The reinforcement assembly includes pretensionable member/s and/or resiliently deformable member/s intermediate of at least one tetherable end of the lengths of chain and a mounting block or link member.
Patent AU-2019335221-A1 (AU)
Title: Combined anchor and fastener assembly especially intended for concrete structures and method employing same
Inventor: NILL LANCE
IPC: E04H12/22
Filed: 2019-09-04
Abstract: A combined anchor and fastener that includes an anchor baseplate having at least one throughbore extending between a top surface and a bottom surface of the anchor baseplate. An elongated post is coupled to the anchor baseplate with an at least partially threaded, internal cylindrical bore for receipt of a mechanical fastener which extends between a first end and a second end of the post whereupon the post internal bore is in alignment and registry with the throughbore of the baseplate. The post includes a second end portion depending from the bottom surface of the anchor baseplate such that the bottom surface of the anchor baseplate is configured to abut and lie generally flush against a portion of a concrete structure apart from a portion which is covered by the post second end portion. The disclosure includes further embodiments as well as a method of anchoring and fastening an object to a concrete structure.
Patent AU-2019338402-A1 (AU)
Title: Network architecture for gaming industry accounting
Inventor: MOHRHARDT DOMINIC
IPC: G07F17/32
Filed: 2019-09-11
Abstract: A peripheral device is installed in a cabinet of an electronic gaming machine and configured to detect and communicate with a personal electronic device of a player of a casino game. The personal electronic device is configured to communicate identity information and/or account information to the peripheral device that, in turn, can be used to enable gameplay on the electronic gaming machine. Other embodiments described herein reference a network architecture facilitating cryptographically-secure and verifiable accounting of all point or real-money transactions in a casino environment.
Patent AU-2019351410-A1 (AU)
Title: Device and method for preparing ultrafine spherical metal powder using drop-by-drop centrifugal atomization method
Inventor: DONG WEI
IPC: B22F9/10
Filed: 2019-09-25
Abstract: A device and method for preparing an ultrafine spherical metal powder by using a drop-by-drop centrifugal atomization method. The device comprises a housing (20), a crucible (2) provided in the housing (20), and a powder collection area. A turntable (8) provided in the powder collection area is an inlaid structure. A material with poor thermal conductivity is selected as a base portion of the turntable (8). A metal material that has a wetting angle of less than 90° with a droplet is selected and inlaid into a main portion as the atomizing plane of the turntable (8). A ventilation hole (24) is provided in the turntable (8). The method for preparing an ultrafine spherical metal powder by means of the drop-by-drop centrifugal atomization method mainly combines the two methods of a uniform droplet ejection method and a centrifugal atomization method, and surmounts a traditional metal splitting mode such that molten metal exhibits fibrous splitting, so that an ultrafine spherical metal powder that has a narrow particle size distribution range, high sphericity, good fluidity, excellent spreadability, a uniform and controllable size, and no satellite droplets may be efficiently prepared, and is suitable for industrial production.
Patent AU-2019355979-A1 (AU)
Title: Drug delivery device having dose indicator
Inventor: PEDERSEN JAKOB HALKJAER
IPC: A61M5/315
Filed: 2019-10-04
Abstract: A drug delivery device includes a housing defining a shell having a proximal end and a distal end and a longitudinal axis extending between the proximal end and the distal end, a needle assembly at least partially disposed within the housing at the proximal end, a drive assembly at least partially disposed within the housing and operably coupled to the needle assembly, and an audible indicator operably coupled to the drive assembly. The needle assembly includes a syringe containing a medicament and a needle or a cannula. The drive assembly is movable between an initial position and a second position that results in the medicament being expelled from the syringe. Upon the drive assembly being positioned in the second position, the audible indicator engages the drive assembly to generate an audible sound indicating the medicament has been expelled from the syringe.
Patent AU-2019356169-A1 (AU)
Title: Safety cab for a mobile home or camper with deformation elements
Inventor: RÖDIGER ANDREAS
IPC: B62D25/02
Filed: 2019-10-11
Abstract: The invention relates to a safety cab for a mobile home or camper, comprising a safety cab part which can be arranged behind the driver's cab. Walls of the safety cab comprise at least one layer of a fiber-reinforced plastic woven fabric and/or non-woven fabric. One layer has plies which follow one another along a transverse direction. Layers directly following one another have different fiber orientations. The layer in the lateral outer walls in a front cab region, when viewed in a provided main travel direction, comprises preferably at least three to nine plies. In a rear cab region, when viewed in a provided main travel direction, the layer in the lateral outer walls comprises preferably one to five plies. Additionally, an intermediate wall is arranged at the transition between the front region of the cab and the rear region of the cab transversely to the longitudinal direction of the cab, wherein the intermediate wall comprises a layer containing three to nine plies. The invention likewise relates to a method for producing a safety cab according to the invention.
Patent AU-2019356502-A1 (AU)
Title: Materials and methods for enhanced carbon utilization and/or sequestration as well as reducing deleterious atmospheric gases
Inventor: FARMER SEAN
IPC: A01N63/10
Filed: 2019-10-08
Abstract: The subject invention provides materials and methods for reducing deleterious atmospheric gases, such as greenhouse gases. In specific embodiments, the reduction in deleterious atmospheric gases is achieved via enhanced vegetative carbon utilization and storage, as well as increased carbon sequestration in soil. In some embodiments, the subject invention can be used for reducing the number of carbon credits used by an operator involved in, e.g., agriculture, livestock production, waste management or other industries. In certain embodiments, the subject invention provides customizable microbe-based products, as well as methods of using these microbe-based products for reduction of greenhouse gases and/or enhanced sequestration of carbon.
Patent AU-2019373643-A1 (AU)
Title: Opening unit
Inventor: BUGAJEW PETER
IPC: B65D85/804
Filed: 2019-10-30
Abstract: The invention relates to an opening unit which can be used, for example, for a packaging material for accommodating a foodstuff product. In one embodiment of the invention, the opening unit according to the invention is provided as part of a capsule which accommodates a substance for preparing a beverage, for example a coffee powder or espresso powder. The invention also relates to a method.
Patent AU-2019374748-A1 (AU)
Title: Dosing regimen of anti-LAG3 antibody and combination therapy with anti-PD-1 antibody for treating cancer
Inventor: ABRAHAM ANSON KUNJACHAN
IPC: A61K39/395
Filed: 2019-11-04
Abstract: The present invention relates to dosing regimens of an anti-LAG3 antibody useful for the treatment of cancer. In particular, the invention relates to the dosing regimen in a combination therapy which comprises administering an antibody of a Programmed Death 1 protein (PD-1) or Programmed Death Ligand 1 (PD-L1) and an antibody of Lymphocyte-Activation Gene 3 (LAG3). The invention also provides a method for treating cancer in a patient comprising administering to the patient an anti-LAG3 antibody and an anti-PD-1 antibody, wherein the tumor tissue section of the patient is PD-L1 expression positive, and optionally LAG3 expression positive.
Patent AU-2019384679-A1 (AU)
Title: Push-fit fitting and end bushing for use therewith
Inventor: WHITNEY JR CHARLIE E
IPC: B29C65/00
Filed: 2019-10-30
Abstract: A plumbing fitting couplable with a free-end portion of a pipe. The fitting has a chamber with an opening and an interior chamber wall with a circumferentially extending chamber groove, and an end bushing with an interior opening sized to receive the pipe free-end portion and an exterior wall portion having an outwardly projecting, circumferentially extending locking member within the chamber groove to resist movement of the end bushing out of the first chamber opening. A seal and gripper ring within the chamber seal with and releasably grip the pipe free-end portion. The end bushing interior opening has an end bushing interior wall portion sized to be engaged by the free-end portion of the pipe when within the end bushing interior opening to resist disengagement of the locking member from the chamber groove while the free-end portion of the pipe is within the end bushing interior opening.
Patent AU-2019388848-A1 (AU)
Title: Small-scale robots for biofilm eradication
Inventor: KOO HYUN
IPC: A01N59/16
Filed: 2019-11-25
Abstract: Systems and methods for eradicating biofilms by killing bacteria within a biofilm, degrading the matrix and removing biofilm debris are disclosed herein. The disclosed subject matter provides techniques for administering a suspension of H
Patent AU-2019390242-A1 (AU)
Title: Skin protectant film including skin health ingredients
Inventor: TAYLOR MICHAEL G
IPC: A61K8/31
Filed: 2019-10-29
Abstract: A no-sting skin protectant film forming composition is formulated with a film forming polymer having both polar and nonpolar characteristics, a no-sting nonpolar solvent system, and at least one skin health ingredient. The no- sting skin protectant film forming composition is configured to form a protective film on a skin surface after the solvent system evaporates.
Patent AU-2019398021-A1 (AU)
Title: Device for emitting light
Inventor: Kübel Johann
IPC: H05K3/00
Filed: 2019-12-10
Abstract: The invention relates to a device (100) for emitting light, in particular for curing substances that cure when irradiated by light, in particular UV light, comprising – an electrical illumination body (1) having at least one thermal contact area (11) and at least two electrical connections (12a, 12b), – wherein thermal energy that arises in the context of the emission of light is able to be dissipated via the thermal contact area (11), – wherein the illumination body (1) is applied to a carrier element (2), – wherein the carrier element (2) has at least one cutout (21) in the region of the thermal contact area (11) of the illumination body (1), – a heat sink (3), which is thermally conductively connected to the thermal contact area (11) of the illumination body (1) in the region of the cutout (21) in the carrier element (2), and – an NTC thermistor (4), which is electrically conductively connected to the electrical connections (12a, 12b) of the illumination body (1), wherein the NTC thermistor (4) is thermally conductively connected to the heat sink (3) and at the same time electrically insulated from the heat sink (3).
Patent AU-2019419750-A1 (AU)
Title: Synthesis of 1,1,2-trifluoro-4-(substituted sufonyl)-but-1-ene
Inventor: ZELL THOMAS
IPC: A01N43/78
Filed: 2019-12-30
Abstract: The present invention provides a process for preparing a compound of formula [I] from a compound of formula [II] using an oxidizing agent and a catalyst, the process is carried out at a low temperature.
Patent AU-2019423115-A1 (AU)
Title: Process for purifying fully humanized anti-EGFR monoclonal antibody
Inventor: LI MINGLI
IPC: C07K16/28
Filed: 2019-07-30
Abstract: Disclosed is a process for purifying a fully humanized anti-EGFR monoclonal antibody, wherein the process comprises treating a culture solution of vectibix antibody cells as follows: performing two-stage deep filtration and clarification, affinity chromatography, low pH incubation and inactivation of a virus, anion exchange chromatography, cation exchange chromatography and concentration and dialysis. The four-step purification process provided by the present invention innovatively integrates processes, such as two-stage deep filtration and clarification, affinity chromatography, low pH incubation and inactivation of a virus, anion exchange chromatography, cation exchange chromatography, concentration and dialysis; and the reaction conditions of the purification process are mild, and same is easy to industrialize, and achieves a purification yield of ≥70% and a stock solution purity of ≥95%, greatly reducing the cost of industrialization. In addition, by means of using a low pH incubation method, not only can pathogens be inactivated without introducing foreign residues, but NGF subunits can also be separated in an acidic environment, and therefore, the method has the advantage of completing two functions with one step.
Patent AU-2019431004-A1 (AU)
Title: Gyration-type crusher
Inventor: KIJIMA TAKASHI
IPC: B02C2/04
Filed: 2019-02-26
Abstract: This gyratory crusher is provided with: a main shaft that is disposed rotatably inside a concavity and that rotates eccentrically with the central axis of the main shaft at an incline to the central axis of the concavity; an upper bearing that rotatably supports an upper end section of the main shaft; a lower bearing that rotatably supports a lower end section of the main shaft; and a hydraulic cylinder that causes the main shaft to move vertically through oil pressure. The lower bearing is provided with an eccentric sleeve that has a main shaft fitting-insertion hole into which the lower end section of the main shaft is inserted to fit rotatably, and an outer cylinder that has an eccentric sleeve fitting-insertion hole into which the eccentric sleeve is inserted to fit rotatably. At least one of an inner peripheral surface of the main shaft fitting-insertion hole, an outer peripheral surface of the eccentric sleeve, and an inner peripheral surface of the eccentric sleeve fitting-insertion hole has a tapered shape in at least a partial region thereof in the axial direction such that the distance from a surface that such tapered shape faces becomes greater as the tapered shape progresses upward.