baber/WOPTO huggingface dataset:
Patent EP-0555693-B1 (EP)
Inventor: OHMACHI YOSHIHIRO
IPC: A61K47/48
Filed: 1993-01-28
Granted: 2001-09-05
Abstract: The present invention provides 1) a method of producing a complex of a fumagillol derivative of the formula: <CHEM> wherein R<1> is hydrogen; R<2> is halogen, N(O)mR<5>R<6>, N + R<5>R<6>R<7>.X- or S(O)nR<5>, wherein R<5>, R<6> and R<7> are independently an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; X- is a counter anion; m is 0 or 1; n is an integer of 0 to 2; and R<5> and R<6> together with the adjacent nitrogen or sulfur atom may form an optionally substituted nitrogen- or sulfur-containing heterocyclic group which may form a condensed ring; or R<1> and R<2> are combined to represent a chemical bond; R<3> is 2-methyl-1-propenyl group or isobutyl group; A is oxygen or NR<8>, wherein R<8> is hydrogen or an optionally substituted lower alkyl or aryl group; and R<4> is hydrogen, an optionally substituted hydrocarbon group or an optionally substituted acyl group; or a physiologically acceptable salt thereof, with a highly water-soluble cyclodextrin derivative, which comprises mixing the fumagillol derivative or a physiologically acceptable salt thereof with the highly water-soluble cyclodextrin derivative into an aqueous solution, the concentration of the highly water-soluble cyclodextrin derivative being at about 100 mg/ml or more, and 2) the complex of the fumaggillol derivative (I) or physiologically acceptable salt thereof with the highly water-soluble cyclodextrin derivative obtained by the production method 1). The complex of the fumagillol derivative (I) or physiologically acceptable salt thereof with the highly water-soluble cyclodextrin derivative is highly soluble in water, highly stable in storage and can be used as a preparation for injection.
Patent EP-0598172-B1 (EP)
Inventor: ZETTNER HANS
IPC: B65D43/10
Filed: 1993-03-05
Granted: 1998-08-12
Abstract: A lid, especially made by thermoforming a sheet of plastic material and used for closing and reclosing a plastic container (1), wherein the lid (5, 15, 55, 65) is provided with a clamping edge (7, 17, 57, 67) which projects downwards and engages below a protruding projection (4) of the container (1), wherein the top wall (6, 16, 56, 66) of the lid extends in a mainly planar manner and is drawn outwards into the edge region, and stacking means (8, 18, 58, 68) being provided, which are located outside the top wall and guarantee a spacing between the adjacent top walls when a plurality of lids are stacked one above the other. <IMAGE>
Patent EP-0600255-B1 (EP)
Inventor: SIGL LORENZ DR
IPC: C04B35/65
Filed: 1993-11-04
Granted: 1995-07-26
Abstract: Composite materials are provided based on titanium diboride and processes for their preparation. The composite materials contain (1) 70 to 98% by volume of titanium diboride, (2) 1 to 15% by volume of Fe2B and (3) 1 to 15% by volume of Ti2O3 and have the following properties: density at least 93% of the theoretically possible density of the total composite material, hardness (HV10) greater than 1,900, bending fracture strength (measured by the three-point method at room temperature) at least 400 MPa and fracture resistance KIC (measured with a sharp incipient crack produced by the bridge method) of at least 4.5 MPa 2ROOT m.
Patent EP-0618968-B1 (EP)
Inventor: MANDELKOW EVA-MARIA
IPC: C12N15/16
Filed: 1992-12-07
Granted: 1999-10-13
Abstract: The invention relates to epitopes of the tau protein which are specifically occurring in a phoshorylated state in tau protein from Alzheimer paired helical filaments, to the use of protein kinases which are responsible for the phosphorylation of the amino acids of the tau protein giving rise to said epitopes, and to antibodies specific for said epitopes. The invention further relates to diagnostic compositions and methods for the diagnosis and/or monitoring of Alzheimer's disease and to the use of said epitopes for the generation of antibodies specifically detecting Alzheimer tau protein.
Patent EP-0630434-B1 (EP)
Inventor: GEURSEN HERMAN JOHAN
IPC: D06M101/16
Filed: 1993-03-12
Granted: 1997-09-24
Abstract: Found are multifilament yarns other than aramid yarns having high swelling values, which makes them suitable for use as a waterblocking reinforcement in communications cables. The yarns are characterised by containing on their surface a layer of a superabsorbent material comprising of from 0.3 to 40 wt.% of the yarn calculated on the dry weight of the yarn. The yarns are obtainable by applying to the surface of a yarn a layer of a water-in-oil emulsion which contains a superabsorbent material in its aqueous phase, the yarn having a swelling value of 100 or higher.
Patent EP-0643814-B1 (EP)
Title: Procede et dispositif visant a verifier une garniture actionnee par un milieu
Inventor: SCHMITT WILFRIED
IPC: F16K37/00
Filed: 1993-05-26
Granted: 1997-04-16
Abstract: L'invention concerne des procédés et des dispositifs visant à vérifier une garniture (1) actionnée par un milieu. A cet effet, pendant un processus de commutation de la garniture (1), les courbes-temps d'une grandeur mesurée relative au système et relative à la garniture sont mesurées. Il est prévu d'une part que la valeur mesurée citée en premier désigne la pression (P1, P2) régnant dans le carter du piston (8) de la garniture (1) et que la seconde valeur mesurée citée concerne la course (H) de la garniture (1). Le coefficient de course de la garniture (1) est dérivé des courbes sous forme de grandeur spécifique du fonctionnement et est mémorisé sous forme de grandeur de base. Lors d'un autre processus de commutation de la garniture (1), la grandeur spécifique du fonctionnement est à nouveau déterminée et on surveille l'écart qu'elle présente par rapport à la grandeur de base mise en mémoire. Des transducteurs permettent d'enregistrer les courbes-temps. La grandeur spécifique du fonctionnement est déterminée dans une unité d'évaluation (20). Il est en outre prévu de déterminer les tendances des écarts que présente une grandeur spécifique du fonctionnement par rapport à la valeur de base associée. On utilise à cet effet une unité de suivi des tendances (26).
Patent EP-0644838-B1 (EP)
Inventor: BLUM ALBERT
IPC: B60V1/11
Filed: 1993-06-16
Granted: 1996-04-10
Abstract: La présente invention concerne un système de compensation pour véhicule à coussin d'air comportant deux moteurs servant à la propulsion, un compresseur servant à créer un coussin d'air au-dessous du véhicule, et un empennage situé à l'arrière du véhicule. Cette invention vise à créer un système de compensation réalisable par des moyens simples pour compenser largement un déplacement du centre de masse du véhicule à coussin d'air. Cette invention est caractérisée par la génération d'une force composante supplémentaire qui compense le déplacement du centre de masse dû à des inégalités de la charge du véhicule par rapport au centre de sustentation. A cet effet, le système directeur de l'air est constitué par un empennage en forme de V renversé (7) dont les faces directrices (9, 10) dirigées vers le bas et munies chacune d'un élément de gouvernail (11, 12) traversent le centre des ouvertures de sortie d'écoulement des turbomoteurs (2, 3).
Patent EP-0598091-B1 (EP)
Title: Functionalized polymer nanoparticles, method of preparation and use thereof
Inventor: LARPENT CHANTAL
IPC: C08F/
Filed: 1993-06-04
Granted: 1997-09-24
Abstract: The present invention relates to polymer nanoparticles caracterized in that they have a narrow grain size distribution, a size comprised between 10 et 50 nanometres and present at their surfaces identical or different ionogenic or reactive groupings. It also relates to the method for the preparation and use of said polymer nanoparticles in the coating industry and in biology.
Patent EP-0639172-B1 (EP)
Inventor: HOEFNAGEL ANTHONIUS JOHANNES
IPC: C07C45/46
Filed: 1993-05-05
Granted: 1998-10-28
Abstract: The invention relates to a process for the preparation of polyhydroxybenzophenones by treating benzoic acid or a derivative thereof with a polyhydroxybenzene or a derivative thereof in the presence of a large pore zeolite as a catalyst.
Patent EP-0630592-B1 (EP)
Inventor: WONG KING CHEE
IPC: A43B21/28
Filed: 1994-06-07
Granted: 1998-04-01
Abstract: Improved sports footwear comprising an insert positioned at least in the heel region, the insert comprising an elastically deformable cellular structure arranged within an elastically deformable air-impermeable casing provided with inner projections on opposing faces, the casing being pneumatically connected to controllable means, rigid with the footwear, for varying the air pressure within the casing so as to modify the elastic characteristics of the insert, each projection on one face being connected to a projection on the other face. <IMAGE>
Patent EP-0638886-B1 (EP)
Inventor: BARBEY PATRICK
IPC: H04L47/32
Filed: 1994-06-29
Granted: 1998-11-11
Abstract: In a method for transmitting a message from a source subscriber station (11..) to a destination subscriber station (11..) in a communications network (12), a configuration service which can be started from a specified subscriber station (11.4) sets the subscriber station (11..) either as repeater station or then as non-repeater station of the communications network (12). The message, which has been provided by the source subscriber station (11..) with a credit value before a first transmission, is retransmitted by a subscriber station (11..), which has been set as repeater station, only if its credit value is not equal to zero, the credit value being reduced by a specific amount each time the message is transmitted. The configuration service ensures that two subscriber stations (11..), set as repeater stations, are so far apart from one another in the communications network (12) that no disturbing interference is produced on the transmission medium by the transmission. <IMAGE>
Patent EP-0659635-B1 (EP)
Inventor: AREGGER KURT
IPC: B62K27/02
Filed: 1994-12-08
Granted: 1998-09-16
Abstract: The motor-cycle frame (11) is connected in a stable manner to the sidecar frame (12). A wheel carrier (2), which here replaces the fork, can be turned laterally for steering purposes. This wheel carrier (2) is coupled in its upper region by means of a longitudinal control arm (3) in vertically movable fashion to the motor-cycle frame (11), whereas in its lower region it is coupled by means of a transverse control arm (4) in vertically movable fashion to a frame member (121) which is connected to the motor-cycle frame (11) and to the sidecar frame (12). As a result, it is possible for the lateral forces, and also for the longitudinal forces, to be very readily picked up approximately in the centre of the wheel and to be diverted onto the low-lying motor-cycle frame (11). <IMAGE>
Patent EP-0619327-B1 (EP)
Inventor: TANAGLIA TIZIANO
IPC: C08F210/00
Filed: 1994-03-31
Granted: 1997-08-06
Abstract: In an improved process for producing elastomeric ethylene-propylene copolymers with a propylene content comprised within the range of from 22 to 38 % by weight and a content of residual chlorine, coming from the co-catalyst, lower than 300 parts per million parts, the polymerization is carried out in suspension in the monomers in the liquid state, with vanadium triacetylacetonate and alkyl-Al compounds, and the obtained polymer is recovered without any washing steps.
Patent EP-0628676-B1 (EP)
Inventor: SCHOEPFER MARIUS
IPC: E04D13/03
Filed: 1994-06-08
Granted: 1998-09-02
Abstract: An inner window reveal (3), in particular for a flat roof window (2), consists partly of chromium-nickel sheet steel which is polished to a high lustre. It consequently exhibits reflective surfaces (30), on which diffuse and direct sunlight is reflected to the maximum extent. There is thus a greater amount of light in the attic room (D), and the room has better light. <IMAGE>
Patent EP-0671983-B1 (EP)
Inventor: SCHWENZFEIER WERNER F
IPC: B21D3/00
Filed: 1993-11-26
Granted: 1997-03-26
Abstract: The invention relates to a process and a linear shaping machine for truing rolled, forged and/or extruded rod-like material. In order to shape the material plastically over its entire cross-section as uniformly as possible so that only minor residual stresses are left after truing, it is proposed that the material be plastically shaped by compression stresses acting along its length while at the same time directed during shaping at least in its plastic flowing region. To this end identical tools (6, 7, 10, 11) in the linear shaping machine can be frictionally applied one behind the other over a partial distance on either side of the material (R) and with a variable distance along the material (R) to opposite surface regions of the material.
Patent EP-0677151-B1 (EP)
Inventor: HASENSTAB WERNER
IPC: F16D7/08
Filed: 1993-11-26
Granted: 1997-07-09
Abstract: In a torque transmitting device with a fixedly adjustable torque limitation, the torque is transmitted to a driven element (3) by a coupling element (4) and a coupling counterelement (5). The coupling counterelement (5) and the coupling element (4) have each a front face (9, 10) located opposite to each other in the direction of the common axis of rotation (11). Several recesses (12, 15) are provided in the area of the front face (9, 10) of the coupling counterelement (5) or coupling element (4). A rolling body (13) arranged in each recess may be pressed into a recess (12, 15) in the opposite front face (9, 10) by a force exerted in the axial direction by a spring (14), so that the coupling element and the coupling counterelement form a kind of ratchet coupling and turn against each other when a determined torque is exceeded. The spring (14) is supported on a stop which may act as a driving element. The device is characterised in that the coupling element (4) and the spring (14) are arranged in an axial space (16) between the coupling counterelement (5) and the stop (2). The spacing between the coupling counterelement (5) and the stop (2) and thus the axial length of said space (16) may be adjusted by moving the coupling counterelement (5) and the stop (16) with respect to each other in the axial direction, but is fixed during operation.
Patent EP-0674533-B1 (EP)
Inventor: AMBROSIO THOMAS J
IPC: A61M11/00
Filed: 1993-12-16
Granted: 1999-03-10
Abstract: PCT No. PCT/US93/12076 Sec. 371 Date Jun. 1, 1995 Sec. 102(e) Date Jun. 1, 1995 PCT Filed Dec. 16, 1993 PCT Pub. No. WO94/14492 PCT Pub. Date Jul. 7, 1994A powder inhaler comprising: a powder housing for holding a supply of powdered material to be dispensed and a metering plate for holding a metered amount of said powdered material, the metering plate being alternately positionable below said supply of powdered material or within an inhalation conduit, by means of a bi-directional, angle-limited relative rotation about a common central axis; a counter for providing a visual count of the number of doses of said powdered material that have been dispensed or remain to be dispensed in response to the relative rotation, the counter including: a continuous counter ring and a coaxially mounted intermittent counter ring, both rings being mounted on a base in surrounding relation to a retaining post, being rotatable about the common central axis and having counting indicia thereon for displaying said visual count; and a display means through which at least one of the counting indicia is displayed to indicate a count corresponding to a number of doses of powdered material that have been dispensed or remain to be dispensed.
Patent EP-0693100-B1 (EP)
Inventor: MACK ARTHUR G
IPC: B01J23/745
Filed: 1994-04-07
Granted: 1998-09-09
Abstract: Procédés de préparation de produits à base de diphénylalcane brominé, qui sont beaucoup plus blancs que de tels produits connus jusqu'ici. Les produits blancs à base de diphénylalcane brominé ainsi obtenus font également partie de la présente invention, ainsi que des formulations comprenant ces produits et des articles préparés à partir de ces derniers.
Patent EP-0694161-B1 (EP)
Inventor: BESTE ANDREAS
IPC: G01L5/16
Filed: 1994-03-22
Granted: 1997-09-03
Abstract: Die Erfindung bezieht sich auf ein Meßrad (2) zum Erfassen von Kräften und Momenten zwischen Felge und Achse eines Fahrzeugrades mit zwischen Felgenstirnseite (8) und einem Radflansch (7) angeordneten Meßwertaufnehmern (6) und mit Mitteln zur energie- und datenübertragenden Kupplung mit einem fahrzeugseitigen Meßwerterfassungs- und -verarbeitungssystem. Nach der Erfindung bestehen der Radflansch (7) und/oder die Felgenstirnseite (8) aus einem Faserverbundwerkstoff, während die radseitigen Mittel (25) zur Energie- und Datenübertragung an der Innenseite des einen Fahrzeugreifen (3) aufnehmenden Felgenbettes (4) angebracht sind und sich im wesentlichen über dessen Umfang erstrecken. Damit ist erreicht, daß das Meßrad (2) hinsichtlich seiner statischen Eigenschaften und seines dynamischen Verhaltens im Fahrbetrieb dem Originalrad weitestgehend entspricht. Meßwertverfälschende Einflüsse, wie erhöhtes Radgewicht und dergleichen treten nicht auf.
Patent EP-0708779-B1 (EP)
Inventor: ALPEGIANI MARCO
IPC: A61K31/545
Filed: 1994-06-24
Granted: 1999-01-27
Abstract: PCT No. PCT/EP94/02059 Sec. 371 Date Mar. 8, 1995 Sec. 102(e) Date Mar. 8, 1995 PCT Filed Jun. 24, 1994 PCT Pub. No. WO95/02603 PCT Pub. Date Jan. 26, 1995The present invention relates to the use of known cephem derivatives of the formula:    <IMAGE>en or an organic radical, R2 represents halo or an organic radical or R1 and R2 taken together with the C-2 carbon atom of the cephem nucleus constitute a carbocyclic or heterocyclyl group; R3 represents R2 as defined above or an organic radical, R4 is either R1 or an organic group, R5 is either R1 as defined above or halo or C1-C6 alkoxy, C1-C6 alkylthio or C1-C6 acylamino; R6 is R2 as defined above or an organic group, or a pharmaceutically acceptable salts thereof.
Patent EP-0713540-B1 (EP)
Inventor: DOLAN SHAWN E
IPC: C23C22/34
Filed: 1994-07-21
Granted: 1998-03-11
Abstract: A chromium free conversion coating at least equivalent in corrosion protective quality to conventional chromate conversion coatings can be formed on metals, particularly cold rolled steel, by a dry-in-place aqueous acidic liquid comprising: (A) a component of anions, each of said anions consisting of (i) at least four fluorine atoms and (ii) at least one atom of an element selected from the group consisting of titanium, zirconium, hafnium, silicon, and boron, and, optionally, (iii) ionizable hydrogen atoms, and, optionally, (iv) one or more oxygen atoms; (B) a component of cations of elements selected from the group consisting of cobalt, magnesium, manganese, zinc, nickel, tin, zirconium, iron, and copper; the ratio of the total number of cations of this component to the total number of anions of component (A) being at least 1:5; (C) sufficient free acid to give the composition a pH in the range from 0.5 to 5.0; (D) a component selected from the group consisting of phosphorus-containing inorganic oxyanions and phosphonate anions; and (E) a component selected from the group consisting of water-soluble and water-dispersible organic polymers and polymer-forming resins.
Patent EP-0719140-B1 (EP)
Inventor: OLEFSKY JERROLD
IPC: C07D263/44
Filed: 1994-09-14
Granted: 2007-10-31
Abstract: A novel method of using thiazolidinedione derivatives and related antihyperglycemic agents to treat populations experiencing impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus (NIDDM) and complications arising therefrom is disclosed.
Patent EP-0665338-B1 (EP)
Inventor: ZANETTE GIANCARLO
IPC: E02D29/14
Filed: 1995-01-04
Granted: 1997-12-03
Abstract: Cover for drainage pits and the like, consists of a first stationary frame (11) made of L-shaped elements fixed to each other and of a second removable frame (12) made of a base (14) and of sidewalls (15) advantageously inclined to the vertical, the second removable frame (12) being inserted into the first stationary frame (11) and comprising at least one engagement and lifting means (16) of a handle type, which is solidly fixed to the second removable frame (12). <IMAGE>
Patent EP-0665329-B1 (EP)
Inventor: SVENSSON SVEN-ARNE
IPC: D21F7/08
Filed: 1991-12-17
Granted: 1998-06-17
Abstract: A press felt is devised for use in a papermaking machine, and a method is provided for manufacturing such a press felt. The press felt comprises a base fabric which is made of fabric of yarn material and is endless in the machine direction of the press felt, and one or more layers of fibre material arranged on the base fabric. The base fabric of the press felt comprises at least one layer composed of a spirally-wound strip (20) made of fabric of yarn material and having a width (w) which is smaller than the width (B) of the final base fabric. Longitudinal threads (22) of the spirally-wound fabric strip of yarn material (20) make an angle  alpha  with the machine direction of the press felt. The fabric strip of yarn material (20) may advantageously be flat-woven. <IMAGE>
Patent EP-0673938-B1 (EP)
Inventor: OKAMOTO KAORU
IPC: A61K31/522
Filed: 1995-03-24
Granted: 1999-07-07
Abstract: An object of the present invention is to offer novel purine derivatives which exhibit an inhibitory action to nasal mucus secretion and are useful as pharmaceuticals, etc. and pharmaceutically acceptable salts thereof. The purine derivatives of the present invention are novel compounds which are represented by the following general formula (I). <CHEM> [In the formula, R is alkyl or cycloalkyl, or optionally-substituted phenyl or phenylalkyl; R' is hydrogen or -COOX; and X is alkyl, alkenyl, alkoxyalkyl, phenyl or phenylalkyl] The compounds of the present invention are useful as therapeutic and preventive agents to various types of rhinitis accompanied by acceleration of nasal mucus secretion and by sneezing reflex such as allergic rhinitis. Moreover, the compounds of the present invention are able to be administered orally and exhibit low toxicity, little side effect and high safety. Accordingly, a continuous administration for long term is possible and they have a very high utility as the drugs.
Patent EP-0693260-B1 (EP)
Inventor: DUBBERKE MARKUS
IPC: F16G11/10
Filed: 1995-07-24
Granted: 1998-09-30
Abstract: The device (1) locks the ends (4) of one or more laces (3) by a basic assembly (6). The assembly comprises a first flat component (12) with protruding hub (13) and with two or more holes (17) clear of the hub; and a cap (5) having a second flat component (7) opposite and clear of the first, also containing two or more holes (11). The cap turns on the basic assembly, the lace ends being passed through the holes and twisted so as to wind them round the hub. This can be arranged to cause the lace ends to cross over each other on the hub. <IMAGE>
Patent EP-0682950-B1 (EP)
Inventor: BRILES DAVID E
IPC: C07K14/28
Filed: 1995-05-19
Granted: 1999-07-21
Abstract: Mucosal administration, particularly intranasally, of killed whole pneumococci, lysate of pneumococci and isolated and purified PspA, as well as immunogenic fragments thereof, particularly when administered with cholera toxin B subunit, provides protection in animals against pneumococcal colonization and systemic infection. The ability to elicit protection against pneumococcal colonization in a host prevents carriage among immunized individuals, which can lead to elimination of disease from the population as a whole.
Patent EP-0706759-B1 (EP)
Inventor: HEGARTY BRYAN MARTIN
IPC: A01N43/80
Filed: 1995-10-11
Granted: 1999-09-22
Abstract: The invention describes a process for controlling contamination of oil production system waters by sessile bacteria, comprising   a) addition of a slug dose of a biologically effective amount of a quick-kill biocide, simultaneously with or followed by b) intermittent addition of a biologically effective amount of a control biocide.   This dosing regime is found to be surprisingly effective when compared with known dosing regimes.