baber/WOPTO huggingface dataset:
Patent CN-1270174-A (CN)
Title: 朱砂根及同属植物中三萜总皂甙及制备方法
Inventor: BIAN BAOLIN
IPC: C07J71/00
Filed: 1999-04-08
Abstract: 本发明是用乙醇或甲醇回流,经大孔树脂提取朱砂根等中所含有的三萜总皂甙成分制成抗肿瘤中药制剂。紫金牛科紫金牛属植物朱砂根(Ardisia.crenate)、紫金牛(A.japonica)、百两金(A..crispa)、罗金树(A..quinquengona)、九节龙(A.pusilla)等植物中,含有2～5%五环三萜总皂甙类成分。这类成分对小鼠多种移植性肿瘤(体内试验)以及多种人瘤细胞(体外试验)均有明显的肿瘤抑制作用,通过数例肿瘤患者口服试用后,其临床检验结果表明具有一定的抗肿瘤活性。
Patent CR-20110079-A (CR)
Title: Anticuerpos neutralizantes del virus anti-influenza y usos de los mismos
Inventor: LANZAVECCHIA ANTONIO
IPC: A61K39/00
Filed: 2011-02-11
Abstract: La presente invención se refiere a anticuerpos, y fragmentos del mismo enlazantes al antígeno, que se enlazan a hemaglutinina y neutralizan un subtipo del grupo 1 y subtipo del grupo 2 del virus de la influenza A.
Patent CR-20120104-A (CR)
Title: Compuestos quimicos
Inventor: DUAN MAOSHENG
IPC: A01N57/00
Filed: 2012-02-28
Abstract: Se describen compuestos de la Fórmula III. También se describen sales de los compuestos, una composición farmacéutica que comprende los compuestos o las sales, y métodos para tratar una infección por HCV a través de la administración de los compuestos o sales.
Patent CR-20180553-A (CR)
Title: Formulaciones de un inhibidor de lsd1
Inventor: LIU YING;
IPC: A61K35/00
Filed: 2017-04-21
Abstract: La presente solicitud hace referencia a formulaciones farmacéuticas y formas de dosificación de un inhibidor de demetilasa 1 específica para lisina (LSD1), o una sal, solvato o hidrato farmacéuticamente aceptable de este, que incluye métodos de preparación de estos, que son útiles en el tratamiento de enfermedades mediadas por LSD1, tales como el cáncer
Patent EC-SP055689-A (EC)
Title: Inhibidor potente de la serina proteasa del vhc
Inventor: CHEN SHIRLYNN
IPC: A61K45/06
Filed: 2005-03-18
Abstract: Se describen composiciones, estuches y métodos farmacéuticos orales, para tratar y prevenir las infecciones del Virus de Hepatitis (VHC) en los que se administra el siguiente Compuesto (1), un inhibidor potente de la serina proteasa del VHC, o una de sus sales farmacéuticamente aceptables, en un intervalo de dosis seleccionado:(1)También se describe el uso de un compuesto de la fórmula (1), o una de sus sales farmacéuticamente aceptables, como una sustancia de control para validar un ensayo de replicación del VHC y también como una sustancia de control para determinar la eficacia relativa de una o más sustancias, sola(s) o en combinación, para inhibir la replicación del VHC.
Patent EC-SP066974-A (EC)
Title: Tapa hermética a prueba de manipulación
Inventor: GANCIA CARLO VITTORIO VALLARINO
IPC: B65D41/34
Filed: 2006-11-08
Abstract: Una tapa hermética particularmente adecuada para botellas de bebidas comprende un elemento sellador (19) que cierra herméticamente una abertura de salida (60) de un envase. Además, la tapa hermética comprende un elemento de seguridad (18) que tiene forma de tapa, por ejemplo, y está adaptado para desplazarse o retorcerse respecto del elemento sellador (10), de una posición cerrada a una posición abierta. Además, se provee un dispositivo indicador (34) para indicar la posición abierta. De acuerdo con la invención, el dispositivo indicador (34) se dispone en un lado exterior (74) del elemento sellador (10) o el elemento de seguridad (18) de manera que el dispositivo indicador (34) es tangible al cambiar de posición y transferirlo de la posición cerrada a la posición abierta.
Patent EC-SP077261-A (EC)
Title: Composición de anticuerpo her2
Inventor: KAO YUNG-HSIANG
IPC: C07K16/32
Filed: 2007-02-16
Abstract: Se describe una composición que comprende una especie principal de anticuerpo HER2 que se une al dominio II de HER2, y una variante de una secuencia de aminoácido del mismo que comprende una extensión líder amino-terminal. También se describen formulaciones farmacéuticas que comprenden la composición, y usos terapéuticos para la composición.
Patent EC-SP099315-A (EC)
Title: Inhibidores de cinasa
Inventor: WALLACE MICHAEL B
IPC: A61K31/513
Filed: 2009-05-08
Abstract: RESUMEN DE LA INVENCIÓNSe proporcionan compuestos para uso con las cinasas que comprenden un compuesto seleccionado del grupo que consiste de la fórmula (I) en donde las variables son como se definen en la presente. También se proporcionan composiciones farmacéuticas, kits y artículos para manufactura que comprenden tales compuestos; métodos e intermediarios útiles para hacer los compuestos; y métodos de uso de los compuestos.
Patent EC-SP109980-A (EC)
Title: Modificación cristalina estable termodinámicamente de 2-({2-cloro-4-(metilsulfonil)-3-[(2,2,2-trifluoroetoxi)metil]fenil}carbonil)ciclohexano-1,3-diona
Inventor: SIXL FRANK
IPC: A01N41/10
Filed: 2010-02-22
Abstract: Nueva modificación cristalina estable termodinámicamente de 2-({2-cloro-4-(metilsulfonil)-3-[(2,2,2-trifluoroetoxi)metil]fenil}carbonil)ciclohexano-1,3-diona . Se describe una modificación cristalina estable termodinámicamente de la sustancia activa herbicida 2-({2-cloro-4-(metilsulfonil)-3-[(2,2,2-trifluoroetoxi)metil]fenil}carbonil) ciclohexano-1,3-diona (tembotriona). Esta modificación cristalina estable termodinámicamente.
Patent EC-SP900613-A (EC)
Title: Alimento sumergible texturizado para peces y camarones
Inventor: KEARNS JOSEPH P
IPC: A23J3/26
Filed: 1990-02-15
Abstract: El presente invento se refiere a un alimento marino texturizado por extrusión, con estrías de proteína contenidas dentro de la microestructura del mismo, formado sin el empleo de ligantes lo que le da un máximo valor nutritivo.. El producto así descrito se mantiene en el agua, sin alterarse por un período mínimo de 4 horas y no está sujeto al ablandamiento, por lo que conserva su atractivo para el pez o camarón.
Patent EC-SP900674-A (EC)
Title: Un metodo para la recuperacion del oro utilizando solucion de dioxido de cloro
Inventor: MASON JOHN Y
IPC: C22B3/00
Filed: 1990-09-19
Abstract: Un método para tratar minerales sulfuros o minerales conteniendo materiales carbónicos para la recuperación de un metal desde allí constando la reacción del mineral con dióxido de cloro por ello para liberar el metal.
Patent EC-SP961937-A (EC)
Title: Inhibidor de proteina quinasa "c"
Inventor: WINNEROSKI LEONARD LARRY
IPC: C08G18/00
Filed: 1996-11-18
Abstract: El invento se refiere a nuevos derivados macrocíclicos bisindolilmaleimida de fórmula: (gráfico) y sus solvatos. La invención proporciona además la preparación, formulaciones farmacéuticas y procedimientos de uso para inhibir la proteína quinasa C en mamíferos.
Patent FI-20070964-A (FI)
Inventor: MAEKI-ONTTO PETRI
IPC: H01F/
Filed: 2007-12-11
Abstract: The object of the invention is a permanent magnet module (2) comprising at least two permanent magnets (6) with the first magnetic pole on the first plane surface (20) and the second magnetic pole on the second plane surface, and a cover (3) at least partially enveloping the permanent magnets (6). According to the invention the cover (3) of the module is magnetically conductive and comprises a top surface, substantially covering the first plane surface (20) of the permanent magnet, and a bottom surface (3), substantially covering the second plane surface of the permanent magnet. The cover (3) is at least partially open at the side surfaces (24) of the permanent magnet (6). Another object of the invention is a rotor for an electrical machine, the rotor having permanent magnets fitted into a corresponding module.
Patent GB-1050101-A (GB)
IPC: C08L23/04
Abstract: 1,050,101. Ethylene polymer compositions. MONSANTO CO. June 24, 1963 [June 25, 1962], No. 25068/63. Heading C3P. A composition comprises a blend of a highpressure ethylene polymer and an ethylenepropylene copolymer in at most 10% by weight of the said ethylene polymer. In examples polyethylene is blended with ethylene-propylene copolymer and carbon black also may be present.
Patent GB-1050580-A (GB)
IPC: D03D45/34
Abstract: 1,050,580 Drop-box looms; beat-up motions. CROMPTON & KNOWLES CORPORATION. Oct. 15, 1963 [Dec. 27, 1962], No. 40590/63. Heading DIE. The speed of a drop-box loom is increased, without increase in shuttle speed, by providing less time per cycle for beat-up and drop-box change. Beat-up motion: The sley 6 is actuated by a crank 88 and spring loaded toggle links 98, 112 whose centre pivot 104 is connected to the loom frame 127 by a link 124 to provide a dwell at back centre. Drop-box motion: The drop boxes 8 to 11 are actuated by pinions 19, 20 which are selectively engaged with a mutilated gear 18 to move cranks 66, 67 to position levers 29, 30 to operate the drop-boxes. The links 77, 81 connecting the cranks 66, 67 to the levers 29, 30 are made longer than is usual to provide smoother operation and thus increase speed of operation.
Patent GB-1053912-A (GB)
IPC: A61K9/00
Abstract: 1,053,912. Calcium solutions for injection. ASTRA APOTEKARNES KEMISKA FABRIKER A.B. Jan. 8, 1965 [Jan. 20, 1964], No. 1030/65. Heading A5B. Aqueous solutions having a calcium content of 6 % to 10% by weight contain a calcium complex obtained by combination of calcium gluconate, calcium lactate, and calcium formate in solution in a molar ratio of 1:1:3.5 respectively. The solution may contain other active ingredients which do not reduce the solubility of the calcium salts, such as magnesium salts, phosphorus compounds, and nikethamide. The solutions may be used for veterinary injections.
Patent GB-1067162-A (GB)
Abstract: 1,067,162. Hydrostatic transmission control. DOWTY MINING EQUIPMENT Ltd., and DOWTY HYDRAULIC UNITS Ltd. April 6 1964 [April 11, 1963; June 4, 1963], Nos 14623/63 and 22205/63. Headings F2C and F2D. A control for a hydrostatic transmission having an engine-driven variable displacement pump 1 in closed circuit with a fixed displacement motor 2 comprises an auxiliary engine driven fixed displacement pump 8 which delivers fluid through a variable throttle valve 17 adjusted by means 51 responsive to the pres sure in the high pressure line between the pump 1 and motor 2 and the pressure drop across the throttle valve 17 is applied through a reversing valve 29 to a spring-centred piston 35 connected by a link 36 to the pump displacement adjusting mechanism. As shown, the throttle valve 17 is connected by links 18, 44, 42 to a manual control lever 39 which is also connected through links 45, 46 to an engine speed governor 7. The device is arranged so that for any particular setting of the governor 7 and throttle valve 17 the pressure drop across the valve 17 produces maximum displacement of the piston 35 and thus maximum displacement of the pump 1. If the load on the motor is such that it slows the engine 6 and pump 8 the pressure drop across the throttle valve 17 is reduced since the pressure drop is proportional to the speed of the pump 8, and permits the springs 37, 38 to move the piston 35 towards the centre position and thus reduce the displacement of the pump 1. The pressure responsive means 51 comprises a spring-loaded piston 53 connected by links 56, 57, 44, 18 to the throttle valve so that excessive pressure in the transmission circuit acts through a line 49 to raise the piston 53 which moves the throttle valve down to reduce the pressure drop across the valve and thus the displacement of the pump 1. The fluid from the pump 8 passes through the throttle valve 17 and non-return valves 21, 22 to the low pressure transmission line 3 or 4 for make-up purposes. Excess fluid leaving the circuit through a shuttle valve 23 and pressure relief valve 26. In Fig. 2 (not shown) the manual control and pressure responsive means act on separate throttle valves arranged in parallel. In Fig. 3 (not shown) the manual control is omitted and the engine governor 7 and throttle valve have predetermined settings, the latter of which may be overridden by the pressure responsive means.
Patent GB-1079359-A (GB)
Abstract: 1,079,359. Calculating devices. OLYMPIA WERKE A.G. Sept. 16, 1965 [April 3, 1965], No. 39591/65. Heading G4B. In a calculating machine for division operations having a slidable intermediate input store 10 into which the dividend and then the divisor are put, an arresting device is provided for the store 10 moving with the divisor in the direction of places of increased significance, which is operative after input of dividend with a number of digits below a fixed number, e.g. 7 and is inoperative after input of a dividend having a number of digits the same as or more than said fixed number. As shown, the arresting device comprises an intercepting lever 18, a detent 28 and a bridge 40 swingable about pin 49. Lever 18 and detent 28 pivot about pins 20 and 29 respectively secured to wall 41 of bridge 40. On input of the dividend, store 10 jumps from denomination to denomination. If the dividend contains seven or more digits, guide lug 16 will engage oblique edge 42b (Fig. 3, not shown) of a projection 42 on bridge 40 thus swinging bridge 40 together with lever 18 and detent 28 clear of lug 16 and allowing store 10 unimpeded movement along guide spindles 14, 15 (Fig. 1, not shown) and clear of shank 3 of division key 2 to make the arresting device inoperative on operation of key 2. Bridge 40 is locked in the position into which it is swung by locking lever 53 (Fig. 1) and is only released on actuation of total key 5. If the dividend contains six or less digits the bridge is not swung and on actuation of key 2, shank 3 strikes portion 21 of lever 18, which rotates the lever so that lug 19 is now located in the path of lug 16. Thus the working off of the dividend begins at the seventh significant place.
Patent GB-1227019-A (GB)
IPC: B21B29/00
Filed: 1968-10-10
Abstract: 1,227,019. Rolling. SOC. NOUVELLE SPIDEM. 10 Oct., 1968 [10 Oct., 1967], No. 48171/68. Heading B3M. A roll of a rolling mill is controllably bent by applying axial forces to the end faces of the two roll journals. The forces are applied by hydraulic pistons 12 located in discs 9 which are coupled together by tie rods 15. The pistons act through semicircular plates 5 positioned above and below the roll neutral axis. The differential pressure applied to the upper and lower plates results in a desired bending of the roll. A common fluid supply is provided for the pistons 12 and members 5, and a sealed casing 24 allows leaked fluid to be returned to the system. An enlarged end may be provided for each roll journal, the end being suitably polished to give a bearing surface. The bending apparatus can be applied to the rolls of a two or four high mill.
Patent GB-1227629-A (GB)
IPC: G03G17/04
Filed: 1968-05-27
Abstract: 1,227,629. Photoelecirophoretic imaging composition. XEROX CORP. 27 May, 1968 [29 May, 1967], No. 25212/68. Heading H1K. A photoelectrophoretic imaging composition comprises an electrically photo-sensitive pigment and #-carotene dispersed in an insulating liquid. The pigment may be a phthalocyanine, a quinacridone, an anthraquinone, a carbazole, a naphthoic acid, ZnO, CdS, CdSe, Fe 2 O 3 , Se, Sb 2 S 3  or As 2 S 3  whilst the insulating liquid may be an unsaturated oil such as olive, cottonseed, chinawood, linseed, castor, pine, cedarwood, peanut, corn, soybean, cod liver or sperm oil. These oils may be used alone or in conjunction with decane, dodecane, tetradecane or kerosene. The composition may also include tricresyl phosphate and styrene. When the composition is used in an imaging process, it is placed on a transparent injecting electrode comprising glass coated with Au, SnO, Cu or Cu 2 I 2  or a cellulose acetate sheet. A blocking electrode in the form of a roll or sheet of conductive rubber, steel, Al, Cu, brass, baryta paper, polyvinyl fluoride, polyurethane, cellulose acetate, polystyrene, P.T.F.E. or polyethylene terephthalate is provided. The pigment image may be fixed by coating it with a thermoplastic layer or transferred to a paper sheet by an electrostatic field or an adhesive tape and there fixed by spraying with a binder or laminating an overlay on it.
Patent GB-1233485-A (GB)
IPC: C08L83/04
Filed: 1969-09-18
Abstract: 1,233,485. Glass plate laminates. WACKERCHEMIE G.m.b.H. 18 Sept., 1969 [25 Sept., 1968], No. 46067/69. Heading B5N. [Also in Divisions B2 and C3] A glass plate laminate may be prepared using as adhesive a mixture of a liquid polydiorganosiloxane (e.g. a cyclic siloxane or a polysiloxane diol) and a polycyclic siloxane containing at least one cyclotrisiloxane ring, and an acid siloxane bond rearrangement catalyst (e.g. a phosphorus nitrochloride).
Patent GB-1234434-A (GB)
IPC: H01L27/00
Filed: 1968-10-02
Abstract: 1,234,434. Integrated circuits. INTERNATIONAL BUSINESS .-MACHINES CORP. 2 Oct., 1968 [5 Oct., 1967], No. 46758/68. Heading H1K. ;[Also in Division H3] The integrated bi-stable -circuit of Fig. la (see- Division H3) comprises an N region 2 forming the collectors and resistors R c , N emitter regions 4 and a P region 3 forming the base and low valued collector resistors R. The diodes are also formed by regions 2 and 3. A P + insulating region 1 surrounds the circuit. In an alternative circuit (Figs. 2a and 2b, not shown) the diodes are connected to taps on resistors R c  and are formed intermediate the transistor region and the centre part of the structure, metallic connections from there to the A<SP>1</SP> terminal forming the low valued resistors R.
Patent GB-1259662-A (GB)
IPC: D04B11/06
Filed: 1969-07-23
Abstract: 1,259,662. Knitting. BOEHRINGER G.m.b.H. GEB. 23 July, 1969 [26 July 1968], No. 36995/69. Headings D1C and D1K. A multisection straight-bar knitting machine comprises, in each section, a pair of narrowing fingers 34 or 134 with transfer points 28, for fashioning the piece being knitted, and movable parallel to the axis of a lace drum attachment 14 over the entire width of the section. As shown, the shaft 16 of lace drum 14 is rotatably and longitudinally mounted within the frame carrying the narrowing fingers 34 of each section. During step wise rotation of drum 14, clips 18 carried thereon operate on levers 20 pivoted on a horizontal pivot 22, one of which is provided for each needle space, to engage lace points 26. Narrowing points 28 are removably secured on each of the narrowing fingers 34 which are secured to members 46, 48 on brackets 42, 44 carried on bars 38, 40. In another arrangement, fingers (134) are carried on bars (138), (140) spaced from the lace drum attachment, Fig. 5 (not shown). The machine produces, e.g. blanks, for garments with lace patterns on lines 10. (For Figures see next page)
Patent GB-1264359-A (GB)
IPC: C10B53/08
Filed: 1969-12-17
Abstract: 1,264,359. Mixing particulate streams. KOPPERS CO. Inc. 17 Dec., 1969 [30 Dec., 1968], No. 61576/69. Heading B1C. [Also in Division C5] An apparatus 63 for blending two streams of heated, particulate coal comprises side passages 127, 129 which communicate through openings 131, 133 with a chamber 135 provided with a weir 139 leading to an outlet 101. The top of the weir is serrated at 141 and a grate in the base of the chamber 135 provides an entrance for hot gases which contact the coal streams which are delivered at 127, 129. A screw conveyor (143), see Fig. 6 (not shown) may be located in the chamber 135.
Patent GB-1264734-A (GB)
IPC: C01B25/12
Filed: 1970-06-12
Abstract: 1,264,734. Phosphorus trioxide. STICKSTOFFWERK PIESTERITZ VEB. 12 June, 1970, No. 28494/70. Heading C1A. Phosphorus trioxide is produced continuously by the oxidation of white phosphorus under reduced pressure in the vapour phase with oxygen-nitrogen mixtures or nitrogen oxides, which may be mixed with oxygen and/or nitrogen. The oxidation gas may be nitrous oxide, nitric oxide or nitrogen dioxide, either alone or mixed with air.
Patent GB-1265166-A (GB)
IPC: G01T1/185
Filed: 1969-02-28
Abstract: 1,265,166. Ionization chambers. INSTYTUT BADAN JADROWYCH. 28 Feb., 1969 [5 March, 1968], No. 10705/69. Heading H1D. [Also in Division G1] A tissue-equivalent differential ionization chamber includes a central measuring electrode 8 surrounded by two semi-cylindrical outer electrodes 6, 7. The voltages supplied to these are such that between electrodes 6 and 8 a region of saturation is produced such that the current is dependent on the total dose rate. Between electrodes 7 and 8 a certain amount of recombination takes place, which reduces the value of current i r  to below is. The difference current i is thus dependent on the recombination effect which is in turn dependent on the quality factor QF of the radiation. Since the dose equivalent (in rems) is dependent on the product of dose rate and QF the current i which is measured by an electrometer 2 with meter 1, is representative of the dose equivalent. The electrometer has a negative feedback loop including a selectable voltage 5 whereby the active volume ratio can be then adjusted to particular constant values, since this voltage control 5 affects the potential between protection ring 1 and measuring electrode 8.
Patent GB-1289147-A (GB)
IPC: H01L21/3063
Filed: 1969-10-08
Abstract: 1289147 Semi-conductor devices PHILIPS ELECTRONIC & ASSOCIATED INDUSTRIES Ltd 8 Oct 1969 [9 Oct 1968] 49383/69 Heading H1K A method of manufacturing semi-conductor devices comprises depositing a P-type epitaxial silicon layer on a low resistivity N-type silicon substrate in such a manner that a high resistivity N-type layer is formed therebetween, the N-type layer protecting the epitaxial layer from etching action in the subsequent selective electrolytic etching process to remove the substrate. The P- type layer may be doped with boron, have a minimum resistivity of 0.5 ohm. cm., and it may be deposited at a substrate temperature of at least 1000‹ C. The substrate may be doped with antimony and have a maximum resistivity of 0.01 ohm. cm. During the etching process, which etch may contain fluorine, a connection may be made to the substrate, but no separate voltage is applied to the epitaxial layer. Finally the high resistivity N-type layer may be removed by chemically etching. Regions of different conductivity types and/or conductivities may also be formed in the epitaxial layer prior to electrolytic etching.
Patent GB-1289655-A (GB)
IPC: H01S3/097
Filed: 1971-04-19
Abstract: 1289655 Lasers UNITED STATES ATOMIC ENERGY COMMISSION 19 April 1971 [25 May 1970] 9952/71 Heading H1C An electron beam 18 of short duration ionizes a pressurized laser gas 11, and causes a capacitor bank 21 applying a voltage less than the gas breakdown voltage to discharge between plate electrodes 14 and produce a stimulated emission output pulse. The gas may be a CO 2 -N 2 -He mixture in the proportions, by volume, of 40% CO 2 , 50% N 2  and 10% He, and is contained in a vessel 13 formed by the electrodes 14, transparent insulating side walls 15, e.g. of sodium chloride, and metal foil walls 16, e.g. of aluminium, transparent to high energy electrons. The capacitor bank is charged from a power supply 24, while the electron beam is generated in an accelerator 12 and is uniformly dispersed through the laser gas by a magnetic field or scattering film 19 and a tapered coupling 20. The device may operate as an amplifier or a generator, a resonator formed by mirrors 17 one of which is slightly transparent being provided in the latter case. The mirrors may be located within the gas. contiguous with the side walls 15 or externally positioned as shown.
Patent GB-1294886-A (GB)
IPC: B42F13/26
Filed: 1969-12-01
Abstract: 1294886 Filing papers NATIONAL BLANK BOOK CO Inc 1 Dec 1969 [3 Dec 1968] 58480/69 Heading B6E A loose leaf binder combines an arched or post binder and a loose leaf ring binder. The openable ring wire elements 42, 42<SP>1</SP>, are spring mounted in a ring metal assembly 28 in the usual way on one side panel 18 of the binder back assembly 18, 20, 16 but the openable ends of the wire elements are clamped in an elongated bar 30 carried on the opposite panel 16. In this manner the wire 42 acts as a post in a post binder. The elongated bar may be a plain or channeled strip and includes a sliding member with lugs, attached to it or punched out of it, which engage over the right-angled ends of the wires and firmly holds them.