baber/WOPTO huggingface dataset:
Patent CA-2855699-C (CA)
Title: Anti-human trop-2 antibody having an antitumor activity in vivo
Inventor: NAKAMURA KOJI
IPC: A61P35/00
Filed: 2012-11-21
Granted: 2021-07-20
Abstract: The present invention provides an antibody (particularly a humanized antibody) specifically reacting with hTROP-2 and exhibiting antitumor activity in vivo, a hybridoma producing said antibody, a composite of said antibody and a drug, a pharmaceutical composition for diagnosing or treating tumors, a tumor detection method, and a kit for detecting or diagnosing tumors.
Patent CA-2857344-C (CA)
Inventor: HARTMAN GEORGE D
IPC: C07D211/54
Filed: 2012-12-21
Granted: 2019-02-12
Abstract: The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.
Patent CA-2857989-C (CA)
Title: An aerosol generating device with a capillary interface
Inventor: DUBIEF FLAVIEN
IPC: A24F40/44
Filed: 2012-12-05
Granted: 2020-06-02
Abstract: There is provided an aerosol generating device comprising a storage portion (113, 501) for storing aerosol-forming substrate (115, 505). The device comprises: a vaporizer (119, 509) for heating the aerosol-forming substrate (115, 505), a capillary material (117, 507) for conveying the liquid aerosol-forming substrate (115, 505) from the storage portion (113, 501) towards the vaporizer (119, 509) by capillary action, and a porous material (201, 301, 405, 511) between the capillary material (117, 507) and the vaporizer (119, 509).
Patent CA-2858164-C (CA)
Inventor: KAMEI NORIYUKI
IPC: A61K31/4439
Filed: 2012-12-07
Granted: 2020-12-15
Abstract: Formule générale (I): La présente invention se rapporte à : un dérivé de pyridone ou un sel de celui-ci représenté par la formule générale (I) ; ou un médicament contenant le dérivé de pyridone ou un sel de celui-ci en tant qu'ingrédient actif. [Dans la formule, le cycle A, R1, R2, R3 et R4 sont des groupes spécifiques].
Patent CA-2859266-C (CA)
Inventor: TUXEN FREDRIK
IPC: G01S13/44
Filed: 2012-12-13
Granted: 2020-01-14
Abstract: La présente invention concerne un capteur permettant de déterminer la direction d'arrivée d'un rayonnement incident sur le capteur. Le capteur comprend des antennes installées selon une configuration particulière différente d'un rectangle, de façon à obtenir des informations à partir de deux paires des antennes positionnées dans les coins d'une grille rectangulaire et des informations supplémentaires à partir d'une antenne supplémentaire formant une troisième paire d'antennes avec une des antennes de la « grille ». L'antenne supplémentaire est placée à une certaine distance des coins et des autres lignes prédéfinies du rectangle/de la grille. De cette manière, par exemple à partir des différences de phase entre les paires d'antennes, une plus grande quantité d'information peut être obtenue par rapport à une configuration dans laquelle les antennes sont seulement positionnées dans les coins d'un rectangle, ce qui permet d'éliminer les angles ambigus de direction d'arrivée sans compromettre la précision de la détermination angulaire.
Patent CA-2865910-C (CA)
Inventor: TANAHASHI HIROYUKI
IPC: C21D8/02
Filed: 2013-03-05
Granted: 2017-10-17
Abstract: La présente invention concerne un matériau en acier embouti à chaud comprenant une composition chimique incluant, en % en masse, 0,18-0,26 % de C, plus de 0,02 % à 0,05 % ou moins de Si, 1,0-1,5 % de Mn, 0,03 % ou moins de P, 0,02 % ou moins de S, 0,001-0,5 % d'Al, 0,1 % ou moins de N, 0,001-0,02 % d'O, 0-2,0 % de Cr, 0-1,0 % de Mo, 0-0,5 % de V, 0-0,5 % de W, 0-5,0 % de Ni, 0-0,01 % de B, 0-0,5 % de Ti, 0-0,5 % de Nb, 0-1,0 % de Cu, et du Fe et des impuretés pour le reste, et caractérisé en ce que: la concentration en inclusions contenant du Mn est de 0,010 % en masse ou plus à moins de 0,25 % en masse ; et le pourcentage, en nombre, des oxydes de Mn dans lesdites inclusions présentant une longueur maximale de 1,0-4,0 µm vaut 10,0 % ou plus. Le matériau en acier embouti à chaud assure une excellente résistance à la fragilisation par l'hydrogène même dans les cas où le matériau en acier, après avoir été embouti à chaud, est soumis à une transformation dans laquelle une contrainte persiste, telle qu'une perforation, et le matériau en acier peut également être travaillé facilement.
Patent CA-2868226-C (CA)
Title: Compressor casing comprising cavities with optimised setting
Inventor: OBRECHT THIERRY JEAN-JACQUES
IPC: F04D29/52
Filed: 2013-04-15
Granted: 2020-01-14
Abstract: The invention relates to a compressor for a turbine engine, comprising: a casing, at least one compressor stage formed by an impeller having stationary blades and an impeller having moving blades (1) positioned downstream of the stationary blade impeller, and cavities (5) in the thickness of the casing that are disposed along a circumference of said casing (4) opposite the moving blades (1). The cavities, which are elongate and extend along a main direction of orientation, are closed upstream and downstream by upstream and downstream faces respectively, and an upstream border (7) and a downstream border (6) are formed at the intersections between same and the casing. The cavities are offset in relation to the moving blades (1) such as to overlap the moving blade impeller in the upstream portion, thereby covering the upstream end thereof. The casing is characterised in that the downstream border (6) of the cavities (5) is oriented parallel to the chord at the head of the moving blade (1).
Patent CA-2874758-C (CA)
Inventor: ZIARNO JAMES J
IPC: G05B23/02
Filed: 2013-06-06
Granted: 2015-10-13
Abstract: A plurality of wireless engine sensors each include a sensing circuit that senses an engine parameter as engine data. A processor configures the sensing circuit to sense at a predetermined sampling rate based on engine operating conditions. A radio transceiver receives and transmits wirelessly the engine data regarding the sensed engine parameters and receives data regarding a sampling rate. An engine monitoring module is mounted at the aircraft engine and a wireless sensor transceiver is configured to receive the engine data regarding sensed engine parameters from the wireless engine sensors. A first wireless transmitter is carried by the housing. A memory is carried by the housing. A processor is coupled to the memory, sensor transceiver and the first wireless transmitter and collects and stores in the memory engine data relating to engine parameters and transmits the engine data via the first wireless transmitter.
Patent CA-2875305-C (CA)
Title: Fbxo3 inhibitors
Inventor: CHEN BEIBEI
IPC: C07D277/28
Filed: 2013-03-13
Granted: 2021-06-01
Abstract: The present application discloses benzathine and related compounds and their use as FBXO-3 inhibitors.
Patent CA-2875700-C (CA)
Title: Materiaux zeolithiques de type cha et leurs procedes de preparation a l'aide de composes de cycloalkylammonium
Inventor: FEYEN MATHIAS
IPC: C01B39/48
Filed: 2013-06-03
Granted: 2020-09-29
Abstract: Cette invention concerne un procédé de préparation d'un matériau zéolithique ayant une structure à ossature de type CHA comprenant YO2 et X2O3, ledit procédé comprenant les étapes suivantes : (1) préparation d'un mélange comprenant une ou plusieurs sources pour YO2, une ou plusieurs sources pour X2O3, et un ou plusieurs composés contenant un cation tétraalkylammonium R1R2R3R4N+ à titre d'agent directeur de structure ; (2) cristallisation du mélange obtenu à l'étape (1) pour obtenir un matériau zéolithique ayant une structure à ossature de type CHA ; Y étant un élément tétravalent et X, un élément trivalent, où R1, R2, et R3 représentent indépendamment les uns des autres un alkyle, et R4 représente un cycloalkyle, et le mélange obtenu à l'étape (1) ne contenant pas de quantité sensible de source pour Z2O5, Z étant P. Des matériaux zéolithiques qui peuvent être obtenus par le procédé selon l'invention, et leur utilisation, sont également décrits.
Patent CA-2880756-C (CA)
Title: Natural personal care cream to powder compositions
Inventor: ANTWI ABENA
IPC: A61K8/92
Filed: 2015-02-03
Granted: 2022-06-21
Abstract: Personal care compositions that apply as a cream and quickly dry to a powdery feel. The compositions comprise a natural starch component (e.g., corn starch), water, one or more emulsifiers, and one or more emollients. The starch, emulsifiers, and emollients are naturally derived, naturally processed, or both. The composition advantageously does not require the addition of synthetic gelling agents or other suspension aids to maintain the starch component in suspension, even with relatively low water concentrations and relatively high starch concentrations. In an embodiment, the emollients include esters of fatty acids and fatty alcohols, as well as a tertiary branched ester (a triester). The emulsifiers may include a sugar ester, alkylaryl glucoside, alkyl aryl alcohol, and straight chain fatty alcohol. An ester of a polyglycerin and a fatty acid (e.g., polyglyceryl-4 caprate) stabilizer has surprisingly been found to provide high temperature phase stability to the composition.
Patent CA-2884675-C (CA)
Inventor: SISLEY JAMES PATRICK
IPC: H01H71/08
Filed: 2013-10-22
Granted: 2020-04-28
Abstract: A position indicator (80) for a circuit breaker (10) is provided. A circuit breaker housing assembly body (30) has an alignment surface (88). The position indicator (80) includes an indicator member (82) having an alignment surface (86) and an elongated spacer member (84). The indicator member (82) is movably coupled to the circuit breaker housing assembly (12) adjacent a terminal screw (54) with the spacer member (84) generally aligned with the terminal screw (54). The indicator member (82) is structured to move between a first position, wherein the alignment surface (86) is not aligned with the housing assembly body alignment surface (88), and a second position, wherein the alignment surface (86) is aligned with the housing assembly body alignment surface (88). The spacer member (84) engages the terminal screw (54) and, if the terminal screw (54) is in a terminal screw (54) first position, the spacer member (84) prevents the indicator member (82) from moving into the indicator member second position.
Patent CA-2887459-C (CA)
Inventor: ZAREMBA GARY W
IPC: F04D13/06
Filed: 2015-04-13
Granted: 2018-11-20
Abstract: An inlet sieve for a self-priming floating pump features a bottom wall that is carried in a position that underlies the inlet of the self-priming floating pump at a distance therebelow with the inlet of the pump aligned with an axis that passes through the bottom wall of the sieve. A perforated outer wall of the sieve stands upward from a top side of the bottom wall and extends about the axis. The bottom wall features an outer area that spans inwardly from the perforated outer wall toward the axis, and a protuberance that bulges upwardly from the outer area to an apex of the protuberance that is situated at the axis. Water flowing inwardly toward the protuberance from different radial directions is directed smoothly upward into the inlet of the pump with minimal turbulence in order to optimize the performance of the pump.
Patent CA-2888301-C (CA)
Inventor: WOOD THOMAS S
IPC: B29C33/42
Filed: 2006-06-13
Granted: 2018-03-13
Abstract: A method for molding a lofted assembly having a lofted material and a laminated nylon support material the garment produced are provided. The method includes the steps of positioning a support fabric on a lofted material; laminating the support fabric to the lofted material to form a lofted assembly; positioning the lofted assembly in a molding apparatus having at least a first mold and a second mold, closing together the first mold and the second mold thereby sandwiching the lofted assembly therebetween and while maintaining a uniform preset gap between said first mold and the second mold so that the inherent loft characteristics of the lofted assembly are substantially preserved.
Patent CA-2895667-C (CA)
Inventor: GUPTA AMAR
IPC: C12M1/34
Filed: 2006-06-27
Granted: 2016-04-26
Abstract: The present invention relates to methods and reagents for modifying the emission of light from labeled nucleic acids for the purpose of real time detection, analysis, and quantitation of nucleic acid sequences, e.g., using singly labeled probes. These methods and reagents exploit advantageous properties of thiazine dyes and diazine dyes. Furthermore, the use of these light emission modifiers in background reduction, nucleic acid duplex stabilization and other uses is also described. Related kits, reaction mixtures and integrated systems are described.
Patent CA-2898724-C (CA)
Inventor: SAKAI KOJI
IPC: C10L5/00
Filed: 2014-02-07
Granted: 2017-02-21
Abstract: In a method for producing residue coal according to the present invention, a solvent is separated by evaporation from a solid material concentrate, which has been separated in a gravity settling vessel (7), in a solvent separator (10), thereby producing a residue coal mixture in which the solvent is remained in the residue coal. Subsequently, the remaining solvent is separated by evaporation from the residue coal mixture in a drier (11), thereby producing the residue coal. In the drier (11), the remaining solvent is separated by evaporation from the residue coal mixture utilizing a heat the residue coal mixture itself has. In this manner, an apparatus for drying the residue coal mixture can be simplified, and the cost required for the drying can be reduced.
Patent CA-2908205-C (CA)
Inventor: UCHIYAMA NAOKI
IPC: C23C14/34
Filed: 2014-03-07
Granted: 2021-02-09
Abstract: This sputtering device (1) is provided with: a vacuum chamber (2); a plurality of targets (8) (8a-8d); a shield (9) for selectively exposing only the target (8c) for film formation within the vacuum chamber (2); a substrate holding unit (11) that holds a substrate (10) at which minute particles flying out from the target (8c) form a film; a first moving unit (14) that moves and holds immobile the substrate holding unit (11); a mask (16) disposed between the target (8c) and the substrate (10); a second moving unit (19) that moves the mask (16)); and a plurality of through-hole units (17a-17f) comprising through-holes (17) that penetrate the mask (16) in a patterned manner.
Patent CA-2917340-C (CA)
Inventor: JACOB CHRISTOPHE
IPC: A45D34/04
Filed: 2014-07-10
Granted: 2018-12-11
Abstract: A molded cosmetic applicator head having a core that supports an array of semi-conical bristles arranged in rows and columns, such that the surfaces of the bristles assume certain orientations, and wherein at least some of the bristles have at one or more prominent depressions and/or prominent protrusions located on a curved surface. A mold for an injection molded applicator head is also described.
Patent CA-2920676-C (CA)
Title: Subsea pumping apparatuses and related methods
Inventor: DALTON JOHN MATTHEW
IPC: C02F1/44
Filed: 2014-08-15
Granted: 2022-07-19
Abstract: This disclosure includes subsea pumping apparatuses and related methods. Some apparatuses include one or more subsea pumps, each having an inlet and an outlet, and one or more motors, each configured to actuate at least one pump to communicate a hydraulic fluid from the inlet to the outlet, where the subsea pumping apparatus is configured to be in fluid communication with a hydraulically actuated device of a blowout preventer. Some subsea pumping apparatuses include one or more of: a desalination system configured to produce at least a portion of the hydraulic fluid; one or more valves, each configured to selectively route hydraulic fluid from an outlet of a pump to, for example, a subsea environment, a reservoir, and/or the inlet of the pump; and a reservoir configured to store at least a portion of the hydraulic fluid. Some apparatuses are configured to be directly coupled to the hydraulically actuated device.
Patent CA-2920705-C (CA)
Title: Compound-resonance driver (crd) bass enhancement system
Inventor: MILLENDER SAMUEL EARL
IPC: G10D13/02
Filed: 2014-07-16
Granted: 2021-09-21
Abstract: A compound resonance driver or CRD may be used to enhance the tonal qualities of a bass drum system or other sound system. A CRD may comprise a flex ring having two hinge pieces. The flex ring may further comprise a plurality of magnets and the flex ring may be easily folded and placed in a drum and then unfolded. A fixed circular component with a complementary magnet orientation may secure the flex ring. The fixed circular component may be attached to outwardly facing components that resonate or otherwise improve upon the sound of a drum or any sound producing, or sound shaping device or instrument, encompassing properties of an acoustic enclosure. The mass and shape of the CRD may increase the excursion of a drumhead. This longer excursion produces a more natural low frequency waveform.
Patent CA-2924527-C (CA)
Title: Compounds for treating prostate cancer
Inventor: WIPF PETER
IPC: A61K31/495
Filed: 2014-09-18
Granted: 2022-07-12
Abstract: A compound, or a pharmaceutically acceptable salt or ester thereof, having a formula I of: R20 - (Z)b - (Y)c - (R21)a - X - R22 - R23 wherein R20 is an aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a silyl-containing group, a boryl-containing group, a phosphine-containing group, amino, a thio-containing group, a seleno-containing group, halide, or a nitro- containing group; Z is alkanediyl, substituted alkanediyl, cycloalkanediyl, or substituted cycloalkanediyl; Y is S, O, or NR10, wherein R10 is H or alkyl; R21 is alkanediyl, substituted alkanediyl, cycloalkanediyl, substituted cycloalkanediyl, alkadienyl, substituted alkadienyl, alkatrienyl, substituted alkatrienyl; X is -C(=0)- or -S(=0)(=0)-; R22 is a moiety that includes at least one divalent amino radical; R23 is an aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a silyl-containing group, a boryl-containing group, a phosphine- containing group, amino, a thio-containing group, a seleno-containing group, halide, or a nitro -containing group; a is 0 or 1; b is 0 or 1; and c is 0 or 1; provided that if X is -C(=0)- then Y is not S.
Patent CA-2926422-C (CA)
Inventor: ANGELO GERALD J
IPC: B62D33/067
Filed: 2014-08-29
Granted: 2016-11-22
Abstract: A cab-over-engine vehicle is described wherein the cab is supported in a level orientation on the vehicle's chassis. A cab repositioning system raises the cab while maintaining the cab in the level orientation, thus exposing the engine to be worked on. A service step structure that is hidden within the exterior body when the cab is over the engine is deployed when the cab is raised. The service step structure is connected to the underside of the cab such that the service step structure swings down and away from the exterior body to provide access to the raised level cab at the same time allowing access to the engine.
Patent CA-2928964-C (CA)
Title: Resorbable, amino acid-based poly(ester urea)s scaffold for vascular graft tissue engineering
Inventor: BECKER MATTHEW
IPC: A61F2/06
Filed: 2014-10-29
Granted: 2022-01-11
Abstract: Embodiments relate to amino acid-based poly(ester urea)s with amino acid residues selected L-leucine, L-isoleucine, L-valine or combinations thereof. The amino acid-based poly(ester urea)S may optionally include a second amino acid residue selected from proteinogenic amino acids and non-proteinogenic amino acids. The amino acid-based poly(ester urea)s are particular useful for the preparation of vascular grafts. Due to the biocompatibility of the amino acid-based poly(ester urea)s, vascular grafts prepared from amino acid-based poly(ester urea)s with small internal diameters (i.e. less than 5mm) may be prepared and inserted into a patient or animal, and provide a substantial decrease in the risk of failure compared to conventional polymers used in vascular grafts.
Patent CA-2934099-C (CA)
Inventor: YU AIPING
IPC: C01B32/182
Filed: 2013-12-20
Granted: 2021-11-16
Abstract: La présente invention concerne un procédé de production de graphène à faible nombre de couches qui comprend l'exfoliation de graphite avec un polymère pour former un composite graphène-polymère et ensuite le traitement du composite pour dissocier le graphène. Le processus d'exfoliation est effectué en utilisant la sonication. Le graphène est dissocié du polymère par une étape de traitement telle qu'une hydrolyse acide. Le procédé produit un graphène très pur.
Patent CA-2935681-C (CA)
Inventor: MACDONALD JOHN T
IPC: E21B21/06
Filed: 2014-12-30
Granted: 2023-01-03
Abstract: L'invention concerne une composition contenant HCI, de l'urée, un chlorhydrate de céto-amine substitué complexe, un alcool, un éthoxylate et une cétone. Ladite composition est employée dans un procédé de solubilisation de carbonate de calcium dans une suspension aqueuse ou dans une dispersion de carbonate de calcium. On décrit une méthode se rapportant à: des traitements de décapage à l'acide, des traitements par pompe électronique submersible (ESP), une fracturation hydraulique, un nettoyage de perforation et une évacuation des débris, à des traitements de préparation de tep pour remplacer l'utilisation de mélanges d'acides acétiques, des traitements de pressage de cément, des traitements de puits d'injection, des traitements de puits de refoulement, l'ajustement du pH de l'eau de fracturation recyclée et/ou des fluides de reflux, l'utilisation de fluide d'ajustement de pH pour aider à l'hydratation de systèmes gelifiés, la rupture de systèmes de fracturation gelifiés pour remplacer l'utilisation d'agents oxydants dangereux, l'utilisation d'un fluide pour décoller un appareil de forage, une fracturation à l'acide, un trempage du bouchon de tête par pression à l'acide, et l'élimination du gâteau de boues.
Patent CA-2936834-C (CA)
Inventor: WILSON DONALD A
IPC: B60C25/02
Filed: 2016-07-22
Granted: 2023-09-12
Abstract: Un dispositif de changement de pneu utilise un assemblage de décolleur de talon avec un outil définissant une paire de surfaces de contact de pneu essentiellement planes et contigües définissant un angle de filet denviron 155 à 165 degrés. Loutil est situé à un angle de filet denviron 55 à 65 degrés par rapport à laxe longitudinal de lassemblage de décolleur de talon allongé.
Patent CA-2949405-C (CA)
Inventor: HINNER MARLON
IPC: C07K14/47
Filed: 2015-05-20
Granted: 2023-08-01
Abstract: The present invention relates to novel, specific-binding therapeutic and/or diagnostic polypeptides directed against the target of Swiss Prot Q16552 and novel, specific-binding therapeutic and/or diagnostic polypeptides directed against the target of Swiss Prot Q9NPF7. In addition, the present invention relates to novel, specific-binding therapeutic and/or diagnostic polypeptides directed against one or both of Swiss Prot Q16552 and Swiss Prot Q9NPF7. The invention also relates to nucleic acid molecules encoding such polypeptides and to methods for generation of such polypeptides and nucleic acid molecules. In addition, the invention is directed to compositions comprising the polypeptides, and therapeutic and/or diagnostic uses of these polypeptides.
Patent CA-2949950-C (CA)
Title: Mur de batiment renforce
Inventor: ESPINOSA THOMAS M
IPC: E04B2/58
Filed: 2014-05-21
Granted: 2019-02-19
Abstract: L'invention porte sur un mur de bâtiment renforcé, qui comprend une fondation; une tige d'ancrage s'étendant de la fondation; un premier colombage disposé au-dessus de la fondation, le premier colombage comprenant une première plaque inférieure et une première plaque supérieure; un second colombage disposé au-dessus du premier colombage, le second colombage comprenant une seconde plaque inférieure et une seconde plaque supérieure; le premier tirant comportant des première et deuxième parties extrémités filetées, la première partie extrémité étant reliée de façon fonctionnelle à la tige d'ancrage; un second tirant comprenant des troisième et quatrième parties extrémités filetées, la troisième partie extrémité étant reliée de façon fonctionnelle à la deuxième partie extrémité du premier tirant.