baber/WOPTO huggingface dataset:
Patent FI-944509-A0 (FI)
Inventor: BENOIT PATRICK
IPC: C12N15/02
Filed: 1994-09-29
Abstract: The invention relates to a monoclonal antibody directed against the human interferon class I receptor (IFN-R) characterized by the following properties: it recognizes the extracellular domain of the human IFN-R, and it has a neutralizing capacity against the biological properties of the human type I-IFN. It further concerns their use for the diagnosis.
Patent FI-964311-A0 (FI)
Inventor: GRONER BERND
IPC: A61K35/14
Filed: 1996-10-25
Abstract: A bifunctional protein comprising: 1) a single-chain antibody directed against a suitable antigen on a tumour cell, 2) a hinge region comprising from about 40 to about 200 amino acids joined to the V<SUB>L </SUB>domain of the single chain antibody, and 3) a functional zeta (zeta) chain from the T-cell antigen receptor (TCR) joined to the hinge region, wherein the hinge region is an immunoglobin-like hinge region which is joined to the C-terminus of the V<SUB>L </SUB>domain of the single-chain antibody. The functional zeta (zeta) chain comprises the transmembrane and the cytoplasmic domain. The bifunctional protein can be expressed using a cytotoxic lymphocyte (CTL) expressing DNA encoding it.
Patent FI-970428-A0 (FI)
Inventor: SEED BRIAN
IPC: A61K35/15
Filed: 1997-01-31
Abstract: Disclosed is a method of treating HIV in a mammal involving administering to the mammal an effective amount of therapeutic cells expressing a membrane-bound, proteinaceous chimeric receptor comprising an extracellular portion which includes a fragment of CD4 which is capable of specifically recognizing and binding the HIV-infected cell but which does not mediate HIV infection. Also disclosed are cells which express these CD4 receptors and DNA and vectors encoding the receptors.
Patent FI-973050-A0 (FI)
Inventor: BOREALIS AS
IPC: C08F210/16
Filed: 1997-07-18
Abstract: The invention relates to a process for the production of an olefin polymer having a desirable molecular weight distribution, comprising: a) feeding to a polymerization equipment: a1) a polymerization material comprising at least one olefin; a2) a catalyst system having at least one catalyst component, which is hydrogen sensitive and under zero or constant hydrogen concentration gives olefin polymer with a narrower molecular weight distribution than the polymer having the desirable broad molecular weight distribution; and a3) hydrogen as a molecular weight regulating agent; b) contacting reactants a1), a2) and a3) during a residence time in the polymerization equipment and under polymerization cnditions to give a polymerization mixture; and c) recovering from said polymerization mixture said polymerization material in the form of the olefin polymer having a desirable broad molecular weight distribution. Said process is characterized in that during said residence time of the contact step b), the partial pressure of hydrogen is varied or allowed to vary continuously or by a repeated cycle.
Patent IL-59051-A0 (IL)
Title: Substituted sulfonic acid anilides their preparation and their use for regulating plant growth
IPC: A01N47/02
Filed: 1979-12-28
Abstract: 1. A substituted sulfonic acid anilide of the formula (I)  see diagramm : EP0013742,P14,F1  where R**1 is alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl (each of up to 12 carbon atoms) or arylalkyl (of 7 to 14 carbon atoms), each of which may be unsubstituted or substituted by halogen, cyano, thiocyanato, azido, nitro, C1-4 -alkoxy, C6-10 -aryloxy, C1-4 -alkylthio, C6-8 -arylthio, C1-4 -alkylsulfinyl, C1-4 -alkylsulfonyl, arylsulfinyl, arylsulfonyl, C1-5 -alkanoyl, C1-5 -alkoxycarbonyl, C1-5 -alkylcarbamyl, di-(C1-5 -alkyl)-carbamyl, C1-4 -alkanoylamino, C1-4 -haloalkanoylamino, C1-6 -alkanoyloxy, C1-4 -alkanoylthio, C1-4 -alkoxycarbonyl-amino, C7-13 -aroyloxy, C1-6 -alkylamino, di-(C1-6 -alkyl)-amino, C6-12 -arylamino, C1-6 -alkylcarbamyl-amino, di-(C1-6 -alkyl)-carbamylamino, C1-6 -alkyl-carbamyloxy, di-(C1-6 -alkyl)-carbamyloxy, C1-4 -alkylaminosulfonyloxy or di-(C1-4 -alkyl)-amino-sulfonyloxy or combinations of these groups, or is cyano, thiocyanato, unsubstituted or C1-4 -alkyl-substituted amino, aminosulfonyl, guanyl, N2 -hydroxyguanyl, hydroximoyl or C1-5 -alkoxy-imidoyl, or is unsubstituted or halogen-substituted C1-4 -alkylsulfenyl or C1-4 -alkylsulfinyl, or is unsubstituted or halogen- and/or C1-4 -alkyl-substituted arylsulfinyl or arylsulfonyl, where aryl is of up to 10 carbon atoms, R**2 and R**3 are identical or different and each is halogen, cyano, thiocyanato, nitro or unsubstituted or halogen-substituted C1-4 -alkyl, C1-4 -alkoxy, C1-4 -alkylthio, C1-4 -alkylsulfinyl, C1-4 -alkylsulfonyl or C1-4 -alkanoyl.
Patent IL-62529-A0 (IL)
Title: New derivatives of cyclopropane carboxylic acid,their preparation,their use in the control of parasites of plants and of animals,the compositions containing them and the new intermediates obtained
IPC: C07C253/30
Filed: 1981-03-30
Abstract: Alpha-cyano-3-phenyl-A-benzyl 2,2-dimethyl 3-((Z).ROOC-CH =CH-)-cyclopropane-carboxylate derivs. of formula (I), as the separate stereoisomers or their mixtures are new (where A is O, -CH2- or -CO, R is 1-8C, opt. unsaturated, linear, branched or cyclic alkyl and the double bond has Z geometry). (I) are parasiticides, esp. insecticides, acaricides and nematocides for plant and animal use. They may be used to control aphids, coleoptera and lepidoptera larvae by application at 10-300 g/hectare. As insecticides they have good killing and knock-down activity, as well as be light-stable and non-toxic to mammals, and may be used to control flies, mosquitos and cockroaches. They are used to control acarier, such as Boophilus ticks (Hgalomnia, Amblyomnia and Rhipicephalus) and mites (sarcoptic,psoroptic and chorioptic). The cpds. may be used in classical formulations, e.g. by spraying onto plants, local application to animal or as animal feed additives.
Patent IL-62649-A0 (IL)
Title: Magnetic polymer latexes and processes for the preparation thereof
IPC: H01F1/00
Filed: 1981-04-14
Abstract: Magnetic-polymer latex having a concentration of less than 65% by weight of hydrophobic vinyl aromatic polymer particles. The polymer particles have diameters from 0.03 to 5 microns and also have dispersed therein a magnetically-charged material in an amount of from 0.5 to 50% by weight with respect to the polymer portion of the polymer particles. A process for preparing magnetic-polymer latices. Magnetically charged particles are dispersed in an organic phase comprising an organically soluble initiator and an organic monomeric component selected from the group consisting of a single vinyl aromatic monomer and a combination of a single vinyl aromatic monomer and a copolymerizing monomer. The dispersion so obtained is mixed with an aqueous solution containing an emulsifying agent and the mixture is homogenized. Polymerization is then effected to form a magnetic-polymer latex containing hydrophobic vinyl aromatic polymer particle. More organic monomer component may be added immediately prior to or during polymerization. Alternatively, the magnetically-charged material may be dispersed into an organic phase comprising an organically soluble initiator and a water-soluble organic compound. An organic monomeric component is added to the aqueous-organic phase mixture after homogenization and prior to or during polymerization, which is effected to form a magnetic-polymer latex containing hydrophobic polymer particles. The magnetic-polymer latices obtained are useful in paints, magnetic tapes, recordings, and biological applications.
Patent IL-70848-A0 (IL)
Title: Cyclic peptides having somatostatin activity
IPC: A61K38/04
Filed: 1984-02-01
Abstract: The invention relates to cyclic hexapeptides of the general formula III   <IMAGE>   in which X represents the radical of an L-aminoacid of the general formula IIIa    <IMAGE> (IIIa)  in which A and B are identical or different and denote alkyl having 1 to 3 carbon atoms, or A and B together represent a saturated, unsaturated or aromatic monocyclic or bicyclic structure having 3 to 6 carbon atoms, n denotes 0 or 1, and Y represents an aliphatic or aromatic L-aminoacid the side chain of which can be hydroxylated, and their salts with physiologically tolerated acids, and to a process for their preparation and their use and their intermediates.
Patent IL-80022-A0 (IL)
Title: Recombinant fibroblast growth factors
IPC: C12N15/18
Filed: 1986-09-12
Abstract: Isolated, cloned recombinant or synthetic DNA sequence encoding acidic or basic mammalian fibroblast growth factors (FGF) are claimed. A DNA sequence, defined above, and including a DNA encoding a heterologous signal sequence upstream of, and operably linked to, the DNA encoding the FGF is also new. It may be operably linked to control sequences for expression. Recombinant host cells transformed with the DNA sequence are claimed. Recombinant vector contg., and effective in expressing, isolated etc. DNA sequence, the DNA sequence encoding FGF being operably linked to control sequences compatible with bacteria or mammalina hosts, is claimed. Prodn. of acidic or basic mammalian FGF comprises cultivation of transformed cells is claimed. Human basic FGF inpurified or recombinant form is claimed.
Patent IL-87273-A0 (IL)
Title: Process for common separation of contaminating elements from electrolyte solutions of valuable metals
IPC: C25C1/12
Filed: 1988-07-29
Abstract: A process for the common or simultaneous separation of arsenic, antimony, bismuth and iron from electrolyte solutions of valuable metals by solvent extraction and subsequent recovery of the contaminating elements, which process is characterized in that aqueous mineral-acidic electrolyte solutions of valuable metals are admixed with a sparingly water soluble organic solvent containing at least one hydroxamic acid, the aqueous and organic phases are thoroughly mixed, the contaminating elements arsenic, antimony and bismuth are precipitated from the organic phase by direct sulfide precipitation, the sulfides are separated, and the extracted iron is subsequently reextracted with a water soluble iron-complexing agent into an aqueous phase and recovered.
Patent IL-87658-A0 (IL)
Title: Lactam derivatives,their preparation and pharmaceutical compositions containing them
IPC: C07D471/04
Filed: 1988-09-02
Abstract: The invention relates to tricyclic lactams of the general formula (I)   <CHEM>  wherein Im represents an imidazolyl group of the formula: <CHEM> and R<1> represents a hydrogen atom or a group selected from C1-6alkyl, C3-6alkenyl, C3-10alkynyl, C3-7cycloalkyl, C3-7cycloalkylC1-4alkyl, phenyl, phenylC1-3alkyl, phenylmethoxymethyl, phenoxyethyl, phenoxymethyl, -CO2R<5>, -COR<5>, -CONR<5>R<6> or -SO2R<5> (wherein R<5> and R<6>, which may be the same or different, each represent a hydrogen atom, a C1-6alkyl or C3-7cycloalkyl group or a phenyl or phenylC1-4alkyl group, in which the phenyl group is optionally substituted by one or more C1-4alkyl, C1-4alkoxy or hydroxy groups or halogen atoms, with the proviso that R<5> does not represent a hydrogen atom when R<1> represents a group -CO2R<5> or -SO2R<5>); one of the groups represented by R<2>, R<3> and R<4> is a hydrogen atom or a C1-6alkyl, C3-7cycloalkyl, C3-6alkenyl, phenyl or phenylC1-3alkyl group, and each of the other two groups, which may be the same or different, represents a hydrogen atom or a C1-6alkyl group;  n represents 2 or 3;  and physiologically acceptable salts and solvates thereof. The compounds are potent and selective antagonists of the effect of 5-HT at 5-HT3 receptors and are useful, for example, in the treatment of psychotic disorders, anxiety, and nausea and vomiting.
Patent IL-95440-A0 (IL)
Title: Substituted urea compounds,their preparation and pharmaceutical compositions containing them
IPC: C07D487/08
Filed: 1990-08-21
Abstract: New substituted urea compounds of formula I, or a pharmaceutically acceptable salt thereof: <CHEM>  wherein  R<1> is a group of formula II, III or IV <CHEM> where n is 2 or 3, p is 1 or 2, q is 1 to 3, r is 1-3 and R<4> and R<5> are H,C1-7 alkyl or C3-6 cycloalkyl; and wherein R<2> is an oxadiazole, substituted with C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, C3-7 cycloalkyl, benzyl, phenyl, C1-6 alkoxy, C1-6 alkylthio, amino or alkylamino; or wherein R<2> is -C-R<6>=N-O-R<7> wherein R<6> is hydrogen or methyl and R<7> is C1-6 alkyl which may be substituted with C3-7 cycloalkyl; and wherein R<3> is hydrogen, halogen, nitro, substituted amine, trifluoromethyl, C1-6 alkyl or C1-6 alkoxy. The compounds are useful in pharmaceutical preparations for treating psychotic disorders, nausea and vomiting.
Patent IL-95864-A0 (IL)
Title: Radiolabeled anticoagulant peptides
IPC: G01N33/60
Filed: 1990-10-01
Abstract: This invention relates to the usage of anticoagulant peptide derivatives that are iodinated. X-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-Y i
Patent IL-99938-A0 (IL)
Title: Hydromechanical control system
IPC: B60G11/18
Filed: 1991-11-01
Abstract: A hydromechanical pressure control system includes a dual pump and cam assembly, which operates in association with an orifice and a relief valve to develop a pressure for operating a multiple disk friction damper. In one embodiment, the friction damper is associated with a torsion bar for spring supporting a vehicle hull on a road arm, which has a spindle for connection to a road wheel, and the cam is configured to operate two pumps to produce a pressure on the friction damper for damping of both jounce and rebound movements of the road wheel relative to the hull, independently of the relative position of the hull and the road wheel during terrain induced movements of the vehicle and its road wheels and wherein a snubber and the torsion bar system improve the energy absorption and energy storage characteristics of the suspension system to thereby improve the ride quality and handling characteristics of said vehicle and to reduce energy requirements when operating off-road. <IMAGE>
Patent FI-20000509-A0 (FI)
Inventor: VAENTTINEN VEIJO
IPC: H04W28/24
Filed: 2000-03-06
Abstract: The invention relates to a radio system which transmits packet traffic and to a method of transmitting service information flexibly between a network part and a terminal in a radio system which transmits packet traffic and in which a connection set-up process is activated by means of a session management arrangement when a connection is established between the terminal (402) and the network part (400). When service information is transmitted between the network part and the terminal, the party needing service activates the connection set-up process and during activation the party needing service indicates the need for service information and the quality of service with a message (602). The party providing service responds with one or more messages (606) which include service information. The connection set-up process is finished without establishing a connection. This way radio path resources can be saved.
Patent FI-20021884-A0 (FI)
Inventor: ILM MYOEH
IPC: C23C4/02
Filed: 2002-10-22
Abstract: A method and apparatus for making a wear resistant coating on a treatment blade ( 4 ), such as a coating, doctor or creping blade, designed for the treatment of a paper web, in which method the area to be coated is subjected to a preliminary treatment before the coating process to improve the adhesion of the coating material. The adhersion surface ( 43 ) of the coating is roughened so that the roughening traces are perpendicular to the longitudinal direction of the coating blade.
Patent FI-20060310-A0 (FI)
Inventor: TRIGLAVCANIN RICHARD
IPC: B01D/
Filed: 2006-03-31
Abstract: The invention discloses an apparatus (1) and method for removing the surface material (2, 3) in connection with clarifying and/or thickening a solids-containing solution, whereby the apparatus comprises a clarification and/or settling tank (4), which is equipped with a feedwell (5) for the slurry to be settled, and discharge ports (6) for removing the thickened slurry and a rake (7) rotating on its drive shaft (8), which rake is for moving the underflow from the edges of the tank to the centre, at least one outer collection launder (9) adjacent periphery (10) of the tank (4), when there is at least one radial element (11) at least partly inside the feedwell (5), when there are means for moving at least part of the surface material (2, 3) into the radial element and means for guiding the surface material outside the feedwell (5).
Patent IL-100889-A0 (IL)
Title: Substituted benzofuranylpiperidine as a nootropic agent
IPC: A61K31/443
Filed: 1992-02-06
Abstract: 4-(7-Bromo-5-methoxybenzofuran-2-yl)piperidine of the formula I <IMAGE> and its pharmaceutically utilisable salts can be used as pharmaceutical active ingredients for slowing down the degeneration of nerve cells associated with degenerative neurological disorders, and as nootropics for the treatment of disorders which respond to nootropic treatment.
Patent IL-101087-A0 (IL)
Title: Derivatives of substituted imidazol-2-one,their preparation and pharmaceutical compositions containing them
IPC: A61K31/4166
Filed: 1992-02-27
Abstract: Derivatives of 1-phenyl-3-azabicycloalkylimidazolidin-2-ones are provided of general formula (I) <CHEM>  in which inter alia R3 represents a group  a) <CHEM>  or b) <CHEM>  wherein n is an integer of 1 or 2 and R8 is hydrogen, C1-C6 alkyl unsubstituted or substituted by phenyl, C2-C4 alkenyl, C2-C4 alkynyl, formyl or C2-C6 alkanoyl; and the pharmaceutically acceptable salts thereof, which are useful in the treatment of CNS disorders, gut motility disorders, emesis and migraine, as cognition activators, anti-drug addition agents and analgesic.
Patent IL-101248-A0 (IL)
Title: Indole derivatives,their preparation and pharmaceutical compositions containing them
IPC: A61P31/10
Filed: 1992-03-16
Abstract: The invention relates to indole derivatives of formula 1,   <IMAGE> 1 in which: R1 and R2 represent H, alkyl, alkenyl, cycloalkyl, N-alkylamino- or N,N-dialkylaminoalkyl, benzyl, pyridylmethyl or phenyl, optionally substituted, R3 and R4 represent H, halogen, alkyl, alkoxy, alkylthio, CF3, NO2, N-alkylamino or N,N-dialkylamino, benzyl or phenyl, optionally substituted, R5 represents H, alkyl, cycloalkyl or optionally substituted benzyl, R6 denotes an alkyl, phenyl or heterocyclic radical, optionally substituted, Z denotes the bivalent radicals -(CH2)n-C(R7R8)-(CH2)p-, -CH=CH-C(R7R8)- in which n=0-2, p=0-2 and n+p</=2, R7 and R8 represent H, alkyl, alkenyl, cycloalkyl, N-alkylamino, N,N-dialkylamino, N-alkylamino- or N,N-dialkylaminoalkyl, benzyl or phenyl, where appropriate substituted, or together form polymethylene or oxa-, thia- or azapolymethylene chains, as well as their tautomeric forms, to processes for preparing them and to their application as hypolipidaemic, antiatheromatous and antidiabetic pharmaceutical products.
Patent IL-108488-A0 (IL)
Title: Chlor-alkali diaphragm electrolysis process and relevant cell
IPC: C25B15/08
Filed: 1994-01-31
Abstract: In a process of chlor-alkali electrolysis carried out in a diaphragm cells comprising pairs of interleaved anodes (B) and cathodes, said cathodes being provided with openings and coated with a porous diaphragm resistant to corrosion, at least part of said anodes (B) being provided with hydrodynamic means (D) to produce circulation of the anodic brine, said cell having inlets (M) for feeding the fresh brine, and outlets for the removal of produced chlorine (H), hydrogen and caustic, the improvement comprising controlling the oxygen content in the chlorine and the chlorate concentration in the caustic independently from the said fresh brine introduced and from the concentration of the said brine by adding an aqueous solution of hydrochloric acid to the brine in the anodic compartment of the cell through a distributor (C) positioned over the hydrodynamic means (D).   <IMAGE>
Patent IL-108943-A0 (IL)
Title: Heterocyclic compounds, their preparation and pharmaceutical compositions containing them
IPC: C07D271/06
Filed: 1994-03-11
Abstract: PCT No. PCT/EP94/00481 Sec. 371 Date Jan. 17, 1996 Sec. 102(e) Date Jan. 17, 1996 PCT Filed Feb. 19, 1994 PCT Pub. No. WO94/21607 PCT Pub. Date Sep. 29, 1994The invention concerns heterocyclic compounds of the general formula (I) in which A, B, R, R2, R3, W, Y, Z1, Z2 and r are as defined in the description, methods of preparing them and their use as inhibitors of thrombocyte aggregation, the metastization of carcinoma cells and the binding of osteoclasts on bone surfaces.   <IMAGE>
Patent IL-109753-A0 (IL)
Title: An electric traction motor vehicle
IPC: B60L50/10
Filed: 1994-05-24
Abstract: PCT No. PCT/IB94/00119 Sec. 371 Date Mar. 21, 1995 Sec. 102(e) Date Mar. 21, 1995 PCT Filed May 24, 1994 PCT Pub. No. WO94/27837 PCT Pub. Date Dec. 8, 1994The vehicle (1) comprises a driving wheel (2) driven by an electric motor (3) whose control circuit (4) is supplied by a generator (6) coupled to a fuel engine (5), and a sensor (18) supplying a power-setting control signal (SC) representative of the position of an accelerator pedal (17) and hence of the desired power that the electric motor (3) has to supply to the wheel (2). To avoid having to provide the vehicle (1) with a large capacity traction battery, the vehicle further comprises means (7, 14 to 16, 19, 20) responsive to the power setting signal (SC) to regulate the rotational speed of the fuel engine (5) to the value at which the latter supplies a mechanical power (Pm) that is equal, firstly, to the desired power and, secondly, to a predetermined fraction of its maximum power.
Patent IL-111892-A0 (IL)
Title: Semiconductive linear element
IPC: H01B11/22
Filed: 1994-12-06
Abstract: A linear element (1,61) suitable for extending between, and being supported by, towers of an overhead electrical power transmission system, includes one or more electrically semiconductive components (54, 62) that cause the element to have a linear resistance of 0.05 to 100 Mohms m<-><1>, and which exhibit a negative temperture coefficient of resistance. The element may be a rope used for stringing up conductors of the system or it may be an optical cable, Preferred materials for forming the semiconductive components include carbonaceous fibre tows formed from pyrolised acrylonitrile fibres. The element has a controllable and reproducible resistance for reducing or eliminating dry-band arcing. <IMAGE>
Patent IL-116784-A0 (IL)
Title: Device for examining viscoelasticity of a living or artificial tissue
IPC: G01N29/07
Filed: 1996-01-16
Abstract: A probe for examining viscoelasticity and anisotrophy of an area of an external layer of a living or artificial tissue, comprises an assembly (34) including at least one group of piezoelectric spaced-apart transducers (78,80,82), each having a surface contact making edge, wherein one of said transducers operates as a transmitter and at least one other transducer operates as a receiver, and wherein said assembly is movable both axially, as well as angularly; means for effecting the controlled axial movement (22,24) of said assembly; means for controlling the contact pressure (24) to be exerted by the transducers on the surface of an area of a tissue to be examined, and means for effecting angular movement of said assembly (18,20) at a selected axial displacement.
Patent IL-122334-A0 (IL)
Title: Orally active adenosine kinase inhibitors
IPC: A61P43/00
Filed: 1996-06-07
Abstract: This invention relates to adenosine kinase inhibitors and to nucleoside analogs, specifically to orally active, substituted 5-aryl pyrrolo[2,3-d]pyrimidine and 3-aryl pyrazolo[3,4-d] pyrimidine nucleoside analogs having activity as adenosine kinase inhibitors. The invention also relates to the preparation and use of these and other adenosine kinase inhibitors in the treatment of cardiovascular and cerebrovascular diseases, inflammation and other diseases which can be regulated by increasing the local concentration of adenosine.