baber/WOPTO huggingface dataset:
Patent WO-2020215044-A1 (WO)
Title: Small molecule-based control of immune cell receptor expression
Inventor: CATE JAMES H DOUDNA
IPC: C12N15/09
Filed: 2020-04-19
Abstract: Translation of an engineered fusion protein is effected with a predetermined small molecule. An engineered human cell for adoptive cell transfer comprises a gene encoding an engineered fusion protein comprising a functional domain, a ribosome stalling signal protector domain, and a ribosome stalling signal wherein translation of the protein is regulatable by a predetermined small molecule targeting the stalling signal. The cell is contacted with the small molecule to induce translation stalling and thereby modulate translation of the protein.
Patent WO-2020242713-A1 (WO)
Inventor: SAVENOK PAVEL
IPC: B65D17/40
Filed: 2020-04-30
Abstract: A re-closeable cap is outfitted upon an upper portion of a beverage can or a series of beverage cans in a multi-pack arrangement for providing a protective barrier atop opened beverage cans. The re-closeable caps include a unibody material construction particularly configured to comprise a cap rim and a cap plate centrally located relative to the cap rim. The cap rim attaches the re-closeable cap to a can rim. The cap plate includes a static portion and at least one dynamic portion all formed from the unibody material construction with complex upper surface landscape and cut lines. The dynamic portions are pivotal relative to the static structure for providing a can-opening access aperture for enabling a user to consume can contents and closing the can-opening access aperture for enabling the user to cover the can opening during contents consumption.
Patent WO-2020227584-A1 (WO)
Inventor: POWELL BRADLEY K
IPC: B65B55/20
Filed: 2020-05-08
Abstract: An automated packaging station is configured to inflate and seal a web material. The automated packaging station includes a rail, a nozzle, and a sealing system. The web material includes a channel that is closed so that the channel can be slid over the rail. The nozzle inserts gas into the channel of the web material, which is in fluid communication with chambers to inflate the chambers. The sealing system seals closed ends the chambers proximate the channel after inflation of the chambers. A shape of the rail causes the channel and an opposite longitudinal side of the web material to diverge either before or during inflation of the chambers by the nozzle.
Patent WO-2020236891-A1 (WO)
Title: Establishing and maintaining secure device communication
Inventor: COHEN DANIEL C
IPC: G06F21/57
Filed: 2020-05-20
Abstract: Techniques for dynamically generating a trust level for an IoT device are described. A plurality of characteristics for a first device of a first device type are analyzed against a set of expected characteristics of the first device type. Embodiments monitor runtime behavior of the first device over a window of time to collect runtime behavior data and analyze the runtime behavior data for the first device to determine whether the device is operating in a manner consistent with the first device type. Upon determining that the analyzed plurality of characteristics is consistent with the set of expected characteristics and that the first device is operating in a manner consistent with the first device type, embodiments generate a security profile for the first device designating the first device as a trusted device.
Patent WO-2020236951-A1 (WO)
Inventor: LAPORTE BRADLEY
IPC: B29C48/88
Filed: 2020-05-20
Abstract: Apparatus and methods for manufacturing compostable, biodegradable drink straws from polyhydroxyalkanoate (PHA) material are disclosed herein. Such apparatus may include a hopper that contains raw PHA material, an extruder that receives the raw PHA material from the hopper and produces extruded PHA material, one or more waters baths that cool the extruded PHA material, a puller that pulls a tubular stream of PHA material through the system, and a cutter that is configured to cut the stream of PHA material into finished straws. The finished straws may be soil- and marine- biodegradable, as well as home- and industrial-compostable.
Patent WO-2020243249-A1 (WO)
Title: Covertly storing a payload of data within a network
Inventor: RANKIN JOHN
IPC: H04J3/14
Filed: 2020-05-28
Abstract: Systems and methods for storing a covert payload of data within a network are provided. A datagram (30) is generated at an origin host (10) comprising the covert payload of data, a more fragments flag (30) indicating that the datagram (30) is part of a larger transmission, a source address (40) for a confederate host (14), and a destination address (42) for a blind host. The datagram (30) is transmitted from the origin host (10) to the blind host (12). When no further datagrams are received, the blind host (12) sends an error message with the covert payload of data to the confederate host (14). This may be repeated across a number of blind (12) and confederate (14) hosts to form a ring (20).
Patent WO-2020247524-A1 (WO)
Inventor: BROWNE IAN RUSSELL
IPC: H01M4/133
Filed: 2020-06-03
Abstract: Methods of forming a composite material film can include providing a layer comprising a carbon precursor and silicon particles on a sacrificial substrate. The methods can also include pyrolysing the carbon precursor to convert the precursor into one or more types of carbon phases to form the composite material film, whereby the sacrificial substrate has a char yield of about 10% or less.
Patent WO-2020257440-A1 (WO)
Inventor: SEN SUSANTO
IPC: G01C21/36
Filed: 2020-06-18
Abstract: Systems and methods are described herein for adjusting a transparency of a map overlay. A mapping application generates for display the map overlay at a first level of transparency depicting at least a portion of a route. The mapping application receives an indication of a current location on the route and based on the current location, detects an upcoming directional change on the route. In response to detecting the upcoming directional change, the mapping application adjusts the transparency of the map overlay to a second level of transparency.
Patent WO-2021034439-A1 (WO)
Title: Integrated assemblies having rugged material fill, and methods of forming integrated assemblies
Inventor: TAPIAS NICHOLAS
IPC: H01L27/1157
Filed: 2020-07-21
Abstract: Some embodiments include a structure having an opening extending into an integrated configuration. A first material is within the opening, and is configured to create an undulating topography relative to a sidewall of the opening. The undulating topography has a surface roughness characterized by a mean roughness parameter R mean  which is the mean peak-to-valley distance along the undulating topography. The R mean  is at least about 4 nm. A second material is within the opening and along at least a portion of the undulating topography. The first and second materials are compositionally different from one another. Some embodiments include integrated assemblies. Some embodiments include methods of forming integrated assemblies.
Patent WO-2021016451-A1 (WO)
Title: Cd63 agonist-related methods and compositions
Inventor: MONTLER RYAN
IPC: C07K14/54
Filed: 2020-07-23
Abstract: Provided are methods of treating cell proliferative disorders. In some embodiments, the methods include administering to a subject having a cell proliferative disorder a therapeutically effective amount of a CD63 agonist, where the CD63 agonist is administered to the subject to enhance a T cell response to abnormally proliferating cells of the cell proliferative disorder. In certain embodiments, the methods include administering to a subject having a cell proliferative disorder a therapeutically effective amount of a CD63 agonist and a therapeutically effective amount of a T cell activator. Also provided are pharmaceutical compositions and kits that find use, e.g., in practicing the methods.
Patent WO-2021021853-A1 (WO)
Inventor: NGUYEN AN DUC
IPC: H04R1/02
Filed: 2020-07-29
Abstract: A mounting system for mounting a loudspeaker to a substrate includes a mounting assembly having an elongated screw, a support member received on and movable along the screw, and a mounting arm rotatably connected to the support member, the mounting arm having a resting position and a working position. The mounting assembly further includes a guide housing which receives the mounting assembly with the screw extending longitudinally therethrough, the guide housing including a wall structure with an open front side and a cap at a top portion of the wall structure. In the resting position, the support member is positioned along the screw to be at least partially received within the cap and the mounting arm is substantially contained within the wall structure. In the working position, the support member is positioned along the screw to be outside of the cap and the mounting arm is spring-biased away from the screw and extends outwardly through the front side of the wall structure.
Patent WO-2021154333-A1 (WO)
Title: Streams on shared database objects
Inventor: CSERI ISTVAN
IPC: G06F16/17
Filed: 2020-07-31
Abstract: A database platform can track changes using a stream that records changes made by database transactions. Streams on views can be implemented by applying a stream to source data, and applying the view to the streamed data. Users of the database platform can query the stream on the view to review recent changes to the view, such as changes made since the last database transaction.
Patent WO-2021026439-A1 (WO)
Inventor: CAMPEAU MICHAEL
IPC: G06Q30/06
Filed: 2020-08-07
Abstract: Systems and methods for tracking the sales of products and presence of advertising materials within a physical store are provided. According to certain aspects, a sensor component disposed within the physical store may detect light emitted by a unique product identifier (UPI) affixed to a product. A processor of the sensor component may analyze the detected light to determine the UPIs, generate a digital representation of the UPIs within a field of view, and transmit at least a portion of the digital representation to a server computer. A plurality of sensor components may track the movement and sales of various products and presence of advertising materials in the physical store, and the server computer may analyze the resulting data to improve merchandising and the sales experience for customers, among other benefits.
Patent WO-2022050947-A1 (WO)
Inventor: ZHU RUI
IPC: H04N3/14
Filed: 2020-09-03
Abstract: An image sensor having a set of pixels making up the image sensor to capture an image. Two or more pixels in the set of pixels each have an architecture that includes multiple photodiodes configurable to form an individual pixel. A control system can cooperate with the multiple photodiodes to form the individual pixel. Each of the multiple photodiodes can have a transfer gate electrically coupled to that photodiode. A common region can hold or transfer charge at least during or after an integration time. A read gate electrically coupled to the common region and a sense node, can supply charge from the common region through the read gate to the sense node.
Patent WO-2021050415-A1 (WO)
Title: Automatic egg cooker
Inventor: LOCRICCHIO LOUIS
IPC: A47J27/00
Filed: 2020-09-08
Abstract: A device for cooking eggs (100) includes a frame (110), a support unit (128), a first burner (126), a top unit (130), a second burner (132), a motor unit (136) and a control unit (140). The support unit (128) defines a recess (129) into which the pan (122) fits. The first burner (126) is adjacent to the recess (129). The top unit (130) is attached to the support unit (128) and defies a second recess (137). The second burner (132) is adjacent to the second recess (137). The motor unit (136) rotates the pan (122) in response to a command. The control unit (140) receives a desired recipe input from a user interface (142) and generates commands that cause the motor unit (136) to operate according to the desired recipe indicated by the input.
Patent WO-2021051056-A1 (WO)
Title: Quick connect electrical connector system
Inventor: CHVALA JOSEPH
IPC: H01R9/26
Filed: 2020-09-14
Abstract: An electrical connector system (10) includes a connector (20) with a plug (50). A shroud (54) extends over a portion of the plug (50) and is coupled with the plug. A conductive socket (14) is configured for receiving the plug (50) of the connector. The socket (14) includes a groove (72) formed on an outer surface thereof. The shroud includes spring fingers (58) having a lock portion (70) thereon configured for engaging the groove (72) for securing the connector (20) in the socket. A collar (80) is slidably mounted on the conductive socket (14) and is configured for sliding between a locked position proximate to the socket groove (72) and an unlocked position. The collar (80) is further configured for engaging the spring fingers (58) of the connector shroud (54) in the locked position to hold the finger lock portions (70) engaged with the groove (72) to lock the connector in the socket.
Patent WO-2021051098-A1 (WO)
Title: Patient-specific surgical methods and instrumentation
Inventor: PERLER ADAM D
IPC: A61B17/68
Filed: 2020-09-14
Abstract: A method may be used to correct a condition present in a patient. The method may include obtaining a first bone model of a first bone of one or more bones of the patient's foot, and using at least the first bone model to generate a cutting guide model. The cutting guide model may define a first bone engagement surface shaped to match a first contour on the first bone, and a first guide feature that, with the first bone engagement surface overlying the first contour, is positioned to guide resection of the one or more bones as part of a surgical osteotomy for correcting the condition. The surgical procedure may be selected from a first group consisting of a bunion correction osteotomy, an Evans calcaneal osteotomy, and a medializing calcaneal osteotomy. The first bone may be selected from a second group consisting a metatarsus, a cuneiform, and a calcaneus.
Patent WO-2021086526-A1 (WO)
Inventor: SUTYAK JOANN
IPC: C08G18/10
Filed: 2020-09-25
Abstract: Disclosed is a moisture reactive polyurethane hot melt adhesive composition that can be applied to substrates at a low coating weight even at application temperatures as low as 60 to 95 °C while retaining the advantageous high tack, green strength, cured bond strength and toughness of conventional high melting point polyurethane hot melt adhesives.
Patent WO-2021076355-A1 (WO)
Title: High temperature printed circuit board substrate
Inventor: FLEMMING JEB H
IPC: H05K1/03
Filed: 2020-10-06
Abstract: The present invention includes a method of creating high temperature mechanically and thermally stabilized PCB fabrication on a photo-definable glass substrate or photosensitive glass substrate.
Patent WO-2021071911-A1 (WO)
Title: Sensor contribution ranking
Inventor: NICULESCU-MIZIL ALEXANDRU
IPC: G06Q50/10
Filed: 2020-10-07
Abstract: Methods and systems for detecting and correcting anomalies include detecting (202) an anomaly in a cyber-physical system, based on a classification of time series information from sensors that monitor the cyber-physical system as being anomalous. A similarity graph is determined (302) for each of the sensors, based on the time series information. A subset of the sensors that are related to the classification is selected (308), based on a spectral embedding of the similarity graphs. A corrective action is performed (206) responsive to the detected anomaly, prioritized according to the selected subset.
Patent WO-2021081031-A1 (WO)
Title: Separation of acetate from fermentation broth
Inventor: ROSIN RICHARD R
IPC: C12N1/20
Filed: 2020-10-21
Abstract: The method of the disclosure comprises fermenting a gas substrate and a microorganism to generate a fermentation broth comprising the microorganism and the target component; passing the fermentation broth to a separation unit having an ion exchange resin in a continuous ion exchange simulated moving bed; selectively retaining the target component through ion exchange with the resin while passing the microorganism through the bed; regenerating the ion exchange resin; and recovering the target component. Alternatively, the fermentation broth is passed to a first separation zone to separate and recycle a first portion of the fermentation broth comprising the microorganism to the bioreactor and then a second portion of the fermentation broth is passed to a second separation zone comprising ion exchange resin which selectively retains the target component through ion exchange with the resin. The remainder is passed through. The ion exchange resin is regenerated, and the target component recovered.
Patent WO-2021081046-A1 (WO)
Title: Micrornas enriched in megakaryocytic extracellular vesicles and uses thereof
Inventor: PAPOUTSAKIS ELEFTHERIOS
IPC: C12N15/11
Filed: 2020-10-21
Abstract: The present invention relates to a method for inducing megakaryocytic differentiation of hematopoietic stem/progenitor cells (HSPCs). The method comprises transferring into the HSPCs an effective amount of small RNAs. The HSPCs may differentiate into megakaryocytes in the absence of thrombopoietin (TPO) and/or without using megakaryocytic microparticles (MkMPs). The small RNAs may be micro RNAs (miRs) selected from the group consisting of miR-486, miR-22, miR-191, miR-181, miR-378, miR-26, let-7, miR-92, miR-126, miR-92, miR-21, miR-146, miR-181, and combinations thereof. For example, the small RNAs are miR- 486 and miR-22. The small RNAs may be synthetic or isolated from cells. Also provided is a method for enhancing megakaryocytic differentiation of HSPCs cultured with megakaryocytic microparticles MkMPs in the presence of an effective amount of one or more exogenous small RNAs (e.g., miR-486).
Patent WO-2021081421-A1 (WO)
Title: Method and system for completing cross-channel transactions
Inventor: HOLLAND IV
IPC: G06Q30/06
Filed: 2020-10-23
Abstract: A high security communication channel between the back-end application and the customer's mobile device is disclosed. An application programming interface that integrates into a service provider's back end application and a software development kit that integrates into a mobile application on the customer's mobile device establish a two-way communication channel between the back-end application and the mobile device. When a customer is ready to complete a transaction in one of the service provider's sales channels, such as online, by phone, in-person, by mobile device, or at a kiosk, the transaction moves to the mobile device for completion. A push message on the mobile device launches the service provider's mobile application and the customer completes the transaction quickly and securely using the advanced automation functions, such as biometrics, GPS, wallet, camera or near field communication, available on the mobile device.
Patent WO-2021086847-A1 (WO)
Inventor: HUFFMASTER ANDREW
IPC: A61B18/02
Filed: 2020-10-27
Abstract: A cryogenic device with a cartridge holder for a cryogen cartridge, cryogen cartridge is coupleable to a cryogen pathway; a probe receptacle for receiving a needle probe, wherein the probe receptacle is configured to couple the needle probe to the cryogen cartridge via the cryogen pathway, and wherein the needle probe comprises: one or more needles having needle lumens disposed therein; a probe extension extending proximally, the probe extension having a probe lumen disposed therein, the probe lumen including an elongate element that extends from a proximal end to a distal end, wherein the probe lumen is coupled to the needle lumens at the distal end, and the cryogen pathway at a first location in between the proximal end and the distal end. Various connection mechanisms for securing needle probes to a handpiece portion are disclosed.
Patent WO-2021133465-A1 (WO)
Title: Système de réalité artificielle doté d'un dispositif d'affichage à focale variable de contenu de réalité artificielle
Inventor: SZTUK SEBASTIAN
IPC: G02B30/52
Filed: 2020-11-01
Abstract: La divulgation concerne des systèmes et des techniques de réalité artificielle destinés à fournir un contenu de réalité artificielle à un utilisateur. Par exemple, un système de réalité artificielle comprend un visiocasque (HMD) configuré pour produire un contenu de réalité artificielle, le HMD comprenant un ensemble de seconds dispositifs de capture d'image configurés pour capturer des données d'image indicatives d'un point focal du regard d'un utilisateur et un dispositif d'affichage à focale variable dont la distance focale peut être modifiée sur la base du point focal de l'utilisateur. De plus, le système comprend un moteur de profondeur configuré pour générer, sur la base des données d'image du monde réel et des données de profondeur associées aux données d'image du monde réel, une scène tridimensionnelle (3D) de l'environnement physique de l'utilisateur et générer un contenu de réalité artificielle sous la forme d'une superposition appliquée à la scène 3D de l'environnement physique en vue d'un affichage sur le dispositif d'affichage à focale variable du HMD sur la base du point focal de l'utilisateur.
Patent WO-2021096946-A1 (WO)
Title: Cancer detection based on four quadrant mapping and matrix analysis of image data
Inventor: CHATTERJEE ARITRICK
IPC: A61B5/055
Filed: 2020-11-11
Abstract: A diagnostic system to analyze imaging data includes a memory configured to store hybrid imaging data of a tissue sample. The system also includes a processor operatively coupled to the memory and configured to generate a four quadrant plot based on the hybrid imaging data. Each point in the four quadrant plot corresponds to an image voxel of the tissue sample. The processor is also configured to determine one or more angle values and one or more distance values for image voxels in the four quadrant plot. The processor is further configured to identify one or more characteristics of the tissue sample based at least in part on the one or more angle values and the one or more distance values. The processor is further configured to perform a matrix analysis of the data, which can be used to identify the one or more characteristics of the tissue sample.
Patent WO-2021101813-A1 (WO)
Inventor: MILICH DAVID R
IPC: A61K39/29
Filed: 2020-11-13
Abstract: The present disclosure relates to hybrid hepadnavirus core antigens including one or more epitopes of a human hepatitis B vims (HBV) antigen. More specifically, the present disclosure relates to hybrid hepadnavirus core antigens in the form of fusion proteins containing a fragment of the PreSl region of the HBV surface antigen inserted in a woodchuck hepadnavirus core antigen. The present disclosure further relates to hybrid hepadnavirus core antigens in the form of fusions proteins containing a truncated HBV core antigen and woodchuck hepadnavirus core antigen. Also provided are nucleic acids encoding the hybrid core antigens, and the use of the hybrid core antigens and nucleic acids for treating HBV-infected individuals.
Patent WO-2021097324-A1 (WO)
Title: Covalent organic frameworks and applications as photocatalysts
Inventor: SUN QI
IPC: B01J35/10
Filed: 2020-11-13
Abstract: Described herein are covalent organic frameworks. The covalent organic frameworks have unique structural and physical properties, which lends them to be versatile in a number of different applications and uses. In one aspect, the covalent organic frameworks are composed of a plurality of fused aromatic groups and electron-deficient chromophores. The covalent organic frameworks are useful as photocatalysts in a number of different applications.