baber/WOPTO huggingface dataset:
Patent CA-2970537-A1 (CA)
Inventor: WAN ZEHONG
IPC: C07D513/12
Filed: 2015-07-21
Abstract: The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example Alzheimer's disease.
Patent CA-2973107-A1 (CA)
Inventor: PULE MARTIN
IPC: C07K19/00
Filed: 2016-02-23
Abstract: The present invention provides a chimeric protein having the formula: Casp-Ht1-Ht2 wherein Casp is a caspase domain; Ht1 is a first heterodimerization domain; and Ht2 is a second heterodimerization domain and wherein, in the presence of a chemical inducer of dimerization (CID), an identical pair of the chimeric proteins interact such that Ht1 from one chimeric protein heterodimerizes with Ht2 from the other chimeric protein, causing homodimerization of the two caspase domains. The invention also provides a cell comprising such a protein and its use in adoptive cell therapy.
Patent CA-2973311-A1 (CA)
Inventor: LIU YIJUN
IPC: B01D21/01
Filed: 2016-03-29
Abstract: Disclosed is a method comprising: a) providing a slurry intended as a feed stream to a solid-liquid separation process; b) removing a slip stream from the slurry; c) measuring at least a portion of the slip stream at a plurality of additive dosage levels to obtain a characteristic indicative of a degree of flocculation, agglomeration, or aggregation for each of the plurality of additive dosage levels; and d) adjusting the solid-liquid separation process.
Patent CA-2973620-A1 (CA)
Inventor: MCLAUGHLIN ROBERT AINSLEY
IPC: G01L1/04
Filed: 2016-01-29
Abstract: La présente invention concerne un dispositif pour évaluer une propriété mécanique d'un matériau, en particulier le module élastique ou de Young. Le dispositif comprend une couche de détection qui a une surface de contact pour entrer en contact avec une surface du matériau. La couche de détection a une propriété ou dimension qui est sensible à la pression. Le dispositif comprend également un détecteur conçu pour détecter un rayonnement électromagnétique qui se propage à travers au moins la couche de détection. Le dispositif est conçu de telle sorte que, lorsque la surface de contact de la couche de détection est en contact avec la surface du matériau, et qu'une charge est appliquée sur au moins une partie de la surface du matériau, le rayonnement électromagnétique détecté peut être utilisé pour déterminer une contrainte dans une partie de la couche de détection, la contrainte déterminée indiquant la propriété mécanique du matériau.
Patent CA-2973747-A1 (CA)
Inventor: DEROUAZI MADIHA
IPC: A61K39/00
Filed: 2016-03-16
Abstract: The present invention provides a novel complex comprising a) a cell penetrating peptide, b) at least one antigen or antigenic epitope, and c) at least one TLR peptide agonist, wherein the components a) - c) are covalently linked. Moreover, the present invention also provides a nucleic acid encoding such a complex, wherein the complex is a peptide or a protein. Such a nucleic acid may be comprised by a vector, and such a vector may be comprised by a host cell. In particular, compositions, such as a pharmaceutical compositions and vaccines are provided, which may be useful for example in the prevention and/or treatment of a diseases and/or a disorder including cancer, hematological disorders, infectious diseases, autoimmunity disorders and transplant rejections.
Patent CA-2977548-A1 (CA)
Title: Procedes et systemes pour une classification taxinomique multiple
Inventor: FLYGARE STEVEN
IPC: C12Q1/68
Filed: 2016-04-22
Abstract: L'invention concerne des procédés pour identifier une pluralité de polynucléotides, ainsi que pour détecter la présence, l'absence, ou l'abondance d'une pluralité de taxons dans un échantillon. L'invention concerne également des systèmes pour la mise en uvre des procédés de l'invention.
Patent CA-2981940-A1 (CA)
Title: Detection amelioree d'adn methyle
Inventor: NAUWELAERS DAVID
IPC: C12Q1/68
Filed: 2016-06-10
Abstract: La présente invention est basée sur la découverte de détection de méthylation sensible et spécifique par a) contrôle de dégradation excessive d'ADN avant une conversion par incubation de réactif de conversion d'ADN (par exemple, réactif au bisulfite) directement avec un échantillon contenant un acide nucléique sans avoir préalablement recours à une purification d'acide nucléique à partir de l'échantillon et sans avoir préalablement recours à une dénaturation d'acide nucléique à des températures élevées de 98 °C, et b) optimisation de l'élimination de bisulfite en commandant le débit de pompage de l'échantillon traité au bisulfite sur une membrane d'extraction à l'intérieur d'un système automatisé.
Patent CA-2982405-A1 (CA)
Inventor: ASIRVATHAM EDWARD
IPC: C09D7/46
Filed: 2016-04-19
Abstract: A coating composition including at least one solvent, at least one resin, at least one drier, and an anti-skinning agent is provided, an anti-skinning composition, wherein the anti-skinning composition comprises at least 92 wt.%, or more particularly at least 98 wt.%, of an alkyl oxime having five carbon atoms selected from 2-pentanone oxime and 3-methyl-2-butanone oxime. In some embodiments, the high-purity 2-pentanone oxime includes less than 0.5 wt.% methyl isobutyl ketoxime. In some embodiments, the composition includes less than 0.006 wt.% methyl isobutyl ketoxime. A method for the preparation of a purified 2-pentanone stream suitable for oximation to a high-purity 2-pentanone oxime is also provided.
Patent CA-2986541-A1 (CA)
Title: Systeme de positionnement
Inventor: PENN JAMES DOUGLASS
IPC: B25J9/02
Filed: 2015-06-01
Abstract: Système et procédé pour un système de positionnement plan pour un élément de sortie, le système comportant une paire de chariots linéaires de coordonnée x et une paire de chariots linéaires de coordonnée y. Le système comporte un mécanisme de guidage pour la paire de chariots linéaires de coordonnée x et pour la paire de chariots linéaires de coordonnée y. Le système comporte une pluralité de câbles de déplacement et contrainte s'étendant depuis la paire de chariots linéaires de coordonnée x et la paire de chariots linéaires de coordonnée y jusqu'à l'élément de sortie pour entraîner la sortie, la paire de chariots linéaires de coordonnée x et l'élément de sortie se déplaçant en synchronisation dans la direction x et la paire de chariots linéaires de coordonnée y et l'élément de sortie se déplaçant en synchronisation dans la direction y. Un mécanisme de retenue retient l'élément de sortie dans un degré de liberté supplémentaire en plus des directions x et y.
Patent CA-2988322-A1 (CA)
Title: Etui de tablette et procede de fabrication
Inventor: MARKS VICTOR L
IPC: A45C11/00
Filed: 2016-06-03
Abstract: L'invention concerne un étui de protection pour un dispositif électronique portable, qui comprend un couvercle articulé comprenant un ensemble de plaques reliées par une feuille de couvercle souple, et un réceptacle qui est relié rotatif et détachable au couvercle par un raccord intermédiaire formant une articulation réglable. Le raccord intermédiaire est accouplé de façon amovible à un élément de couplage fixe qui est contenu dans l'épaisseur de l'une des plaques du couvercle, de telle sorte que le couvercle assemblé peut être fabriqué par pression dans une presse ou machine de fabrication d'étui classique. Le réceptacle comprend un verrou flexible et un évidement, l'utilisateur pouvant insérer un bout de doigt pour soulever le dispositif à partir du réceptacle.
Patent CA-2990500-A1 (CA)
Inventor: VITTORIAS IAKOVOS
IPC: C08L23/06
Filed: 2016-06-06
Abstract: A polyethylene composition particularly suited for producing pipes, having the following features: 1) density from 0.945 to 0.958 g/cm3, determined according to ISO 1183 at 23°C; 2) ratio MIF/MIP from 20 to 43; 3) MIF from 4.0 to less than 8.5 g/10 min.; 4) HMWcopo index from 3.5 to 20; 5) long-chain branching index, LCBI, equal to or lower than 0.82.
Patent CA-2994852-A1 (CA)
Inventor: NEWMAN GREG
IPC: G02B19/00
Filed: 2016-08-19
Abstract: An apparatus. The apparatus includes a detector array having a plurality of elements, and a photosensitive region disposed about the plurality of elements. Circuitry coupled the elements of the detector array is configured to generate a set of first signals based on optical energy impinging on a respective one of the plurality of elements of the detector array. Circuitry coupled to the photosensitive region is configured to generate a second signal having a first value if no portion of optical energy impinging on the plurality of elements of the detector array impinges on the region disposed about the elements of the detector array. The second signal has a second value if a portion of an optical energy impinging on the plurality of elements of the detector array impinges on the photosensitive region disposed about the elements of the detector array and the portion exceeds a threshold energy.
Patent CA-2995314-A1 (CA)
Inventor: LACORTE ANDREA
IPC: C11C3/08
Filed: 2016-08-09
Abstract: The present invention relates to a process for preparing a mixture of cetylated fatty acids and a system for carrying out said process. Furthermore, the present invention relates to a composition comprising, or alternatively, consisting of said mixture of cetylated fatty acids. Finally, the present invention relates to said composition for use in the treatment and/or prevention of: (i) rheumatoid arthritis of inflammatory and non-inflammatory origin, in particular osteoarthritis; (ii) other inflammatory joint conditions; (iii) psoriasis, lupus, periodontal diseases or cardiovascular or heart diseases; (iv) all post-traumatic osteoarticular pathologies including sports injuries; (v) all degenerative joint pathologies (arthrosis, gonarthrosis, coxarthrosis, etc.), and (vi) inflammatory-traumatic tendon and muscular conditions. Furthermore, it is envisaged that the composition of the present invention be used in the treatment and/or prevention of the above-mentioned pathologies and disorders (i)-(vi) in association with a rehabilitative therapy. The composition comprising said mixture is formulated in a pharmaceutical form for oral use (novel food, supplement or medical device), i.e. in the form of a pill, pastille, capsule, tablet, granules, dispersible powder, syrup, solution or sprayable solution; for topical use, i.e. in the form of a cream, unguent, ointment, gel or spray to be used as such for application on the skin, or else for transdermal use in the form of a patch.
Patent CA-2997084-A1 (CA)
Inventor: KOSEL CHRISTOPHER J
IPC: E21B33/129
Filed: 2018-02-28
Abstract: A downhole tool for a wellbore and method of assembly. Components of the tool include a load member, one or slip members, one or more compression members, and a sealing element between the compression members mounted on a mandrel. The components are designed to prevent pre-set of the tool in the wellbore and facilitate removal of the tool from the wellbore.
Patent CA-2997093-A1 (CA)
Inventor: SAJWAN RAVINDER
IPC: A61B5/0408
Filed: 2016-08-31
Abstract: A wireless medical system for remotely monitoring, detecting, and/or diagnosing a patient. The system includes a patch, a data transfer mechanism, and an assistive interpretation module. The system can also include additional modules or components without deviating from the spirit of the invention.
Patent CA-2999114-A1 (CA)
Title: Dispositifs et procedes d'analyse du comportement d'un animal
Inventor: ROBERSON DAVID P
IPC: A01K1/03
Filed: 2016-09-16
Abstract: L'invention concerne un dispositif de détection et d'enregistrement du comportement d'un animal. Le dispositif comprend au moins une enceinte définissant un champ délimité, la surface de base de ladite enceinte étant sensible aux empreintes de l'animal. Le dispositif comprend également un dispositif de capture d'image qui coopère avec la surface de base pour capturer une première vidéo dans laquelle la queue et/ou le corps et/ou la tête de l'animal sont éclairés par une lumière au-dessous de l'animal, et une seconde vidéo dans laquelle le profil de toute l'empreinte de l'animal et le profil de l'empreinte des orteils de l'animal lorsque celui-ci se tient sur ses orteils sont éclairés par une lumière entièrement réfléchie intérieurement au sein de la surface de base. Un système de commande sert à commander le dispositif de capture d'image pour capturer la première et la seconde vidéo.
Patent CA-2999527-A1 (CA)
Inventor: WORT CHRISTOPHER JOHN HOWARD
IPC: C30B25/18
Filed: 2016-09-14
Abstract: A method of fabricating a plurality of single crystal CVD diamonds, the method comprising: coating a carrier substrate with a layer of polycrystalline CVD diamond material; bonding a plurality of single crystal diamond substrates to the layer of polycrystalline CVD diamond material on the carrier substrate; growing single crystal CVD diamond material on the plurality of single crystal diamond substrates to form a plurality of single crystal CVD diamonds; and separating the plurality of single crystal CVD diamonds from the layer of polycrystalline CVD diamond material on the carrier substrate and any polycrystalline CVD diamond material which has grown between the plurality of single crystal CVD diamonds to yield a plurality of individual single crystal CVD diamonds.
Patent CA-3001338-A1 (CA)
Title: Bande intra-annulaire transvalvulaire pour reparation de valvule mitrale
Inventor: HULME GARY
IPC: A61F2/24
Filed: 2016-10-13
Abstract: La présente invention concerne le traitement du prolapsus valvulaire mitral et de la régurgitation mitrale par implantation, dans l'anneau mitral, d'une bande intra-annulaire transvalvulaire. La bande présente une première extrémité, une première partie d'ancrage placée à proximité de la première extrémité, une seconde extrémité, une seconde partie d'ancrage située à proximité de la seconde extrémité, et une partie centrale. La partie centrale est placée de manière à s'étendre transversalement sur un bord de coaptation formé par la fermeture des feuillets valvulaires mitraux. La bande peut être implantée par accès transluminal ou par thoracotomie.
Patent CA-3004088-A1 (CA)
Title: Enzymatic treatment of plant oil
Inventor: SOE JORN BORCH
IPC: C11B3/02
Filed: 2012-02-16
Abstract: In one aspect, there is provided a process for treating a plant oil, comprising a step of contacting the oil with an enzyme, wherein the enzyme is capable of hydrolysing an a' or b' stereoisomer of chlorophyll or a chlorophyll derivative.
Patent CA-3005383-A1 (CA)
Title: Reciprocating skate blade sharpener
Inventor: FROMMER THOMAS P
IPC: B24B9/04
Filed: 2009-12-21
Abstract: In one aspect, the invention is directed to a sharpener for sharpening a snowice travel member such as a skate blade, a ski or a snowboard, which includes a sharpening surface that is movable lengthwise along an edge face of the item to be sharpened. The sharpening surface may be movable lengthwise by means of a motor and a reciprocating mechanism, or may be manually moved by a user.
Patent CA-3005809-A1 (CA)
Title: Derives d'iminotetrahydropyrimidinone utilises comme inhibiteurs de plasmepsine v
Inventor: CHARLTON REBECCA LOUISE
IPC: C07D471/04
Filed: 2016-11-24
Abstract: L'invention concerne une série de dérivés de 2-imino-6-méthyltétrahydropyrimidin-4(lH)-one, substitués en position 6 par une fraction phényle qui, à son tour, est méta-substituée par un système bicyclique fusionné insaturé éventuellement substitué contenant au moins un atome d'azote, lesdits dérivés étant des inhibiteurs sélectifs de l'activité de la plasmepsine V, et étant bénéfiques comme agents pharmaceutiques, en particulier pour le traitement du paludisme.
Patent CA-3008439-A1 (CA)
Title: Self-adjusting earth-boring tools and related systems and methods
Inventor: RICKS GREGORY L
IPC: E21B10/42
Filed: 2016-12-14
Abstract: A self-adjusting earth-boring tool includes a body carrying cutting elements and an actuation device disposed at least partially within the body. The actuation device may include a first fluid chamber, a second fluid chamber, a first reciprocating member, and a second reciprocating member. The first and second reciprocating members may divide portions of the first fluid chamber from portions of the second fluid chamber. A connection member may be attached to both of the first and second reciprocating members and may have a drilling element removably coupled thereto. A first fluid flow path may extend from the second fluid chamber to the first fluid chamber. A second fluid flow path may extend from the first fluid chamber to the second fluid chamber.
Patent CA-3008443-A1 (CA)
Inventor: HENRY WILLIAM
IPC: B01F5/06
Filed: 2016-12-21
Abstract: The present disclosure relates to catalytic static mixers comprising catalytic material. The static mixers can be configured for use with continuous flow chemical reactors, for example tubular continuous flow chemical reactors for heterogeneous catalysis reactions. This disclosure also relates to processes for preparing static mixers. This disclosure also relates to continuous flow chemical reactors comprising the static mixers, systems comprising the continuous flow chemical reactors, processes for synthesising products using the continuous flow reactors, and methods for screening catalytic materials using the static mixers.
Patent CA-3008950-A1 (CA)
Inventor: CHAVANA ERNEST MATTHEW
IPC: A47L11/30
Filed: 2018-06-19
Abstract: An apparatus includes a body, a first tank and a second tank. The body includes a first fluid coupling and a first air passage. The first tank includes a first vessel configured to accommodate a fluid and a second fluid coupling communicatively coupled with the first fluid coupling. The second tank includes a second vessel separated from the first vessel and a second air passage communicatively coupled with the first air passage. The apparatus also includes a tank base over the body. The tank base includes a first tank seat configured to accommodate the first tank and a second tank seat configured to accommodate the second tank. The tank base is configured to be separated from the body with at least one of the first tank in the first tank seat or the second tank in the second tank seat.
Patent CA-3008997-A1 (CA)
Inventor: GOVARI ASSAF
IPC: A61B18/14
Filed: 2018-06-21
Abstract: Apparatus, including a catheter configured to be inserted into an organ of a human body. A plurality of electrodes are deployed on the catheter, the electrodes being configured to transfer radiofrequency (RF) ablation energy to tissue of the organ. The apparatus also includes a power supply configured to supply the RF ablation energy at a level of up to 100W to each of the plurality of electrodes simultaneously, so as to ablate respective sections of the tissue of the organ in contact with the electrodes.
Patent CA-3010564-A1 (CA)
Inventor: YOON SEONG JUN
IPC: A61K9/00
Filed: 2017-01-09
Abstract: A method of treating staphylococcal infections includes administering to a subject an effective amount of an antibacterial composition having a broad bactericidal activity. The antibacterial composition includes a first antibacterial protein consisting of the amino acid sequence as set forth in SEQ. ID. NO: 1 and/or a second antibacterial protein consisting of the amino acid sequence as set forth in SEQ. ID. NO: 2.
Patent CA-3011924-A1 (CA)
Title: Reversible sighting putter
Inventor: PELECHOSKY DONALD S
IPC: A63B69/36
Filed: 2018-07-20
Abstract: A golf putter that enables dual configuration, namely sighting & play modes whereby the golfer can view both the ball and the hole by means of a mirrored surface, but which is reversible so that the golfer can play within tournament rules. A removable mirrored training aid has a reflective side and can be removed, flipped to a non-reflective side, or simply replaced with a same-weighted non-reflective plate, for use in actual (non-practice) golf play.  The golfer can practice his or her stroke while observing the image of the ball and hole in the mirror, and thereby imprinting the correct stroke mechanics into muscle memory. Then, after the golfer has reversed the re-attachable mirrored surface plate to present its non-reflective side, the golfer can use the putter in a round of golf.
Patent CA-3012799-A1 (CA)
Inventor: DELONG RYAN W
IPC: B60P7/02
Filed: 2018-07-30
Abstract: A tonneau cover can include at least one pair of cooperating locking elements coupled thereto with the cooperating locking elements being positioned to engage and automatically lock with each other when rearward sections of the tonneau cover are folded onto the forward section and into a stack. Thus, the cooperating locking elements can operate to retain the sections together in the stack when locked with each other.
Patent CA-3015991-A1 (CA)
Inventor: AOSHIMA YUKI
IPC: G02F1/155
Filed: 2017-02-07
Abstract: A multilayer substrate for electrochromic light control elements, which comprises a glass substrate and a transparent conductive film, and wherein: the glass substrate contains silicon oxide, aluminum oxide, boron oxide, alkaline earth metal oxides and alkali metal oxides in a total amount of 90 mol% or more, while containing the alkali metal oxides in a total amount of 12 mol% or less; the transparent conductive film sequentially comprises, from the glass substrate side in the following order, an indium oxide film containing tin and a tin oxide film containing one or more elements selected from among tantalum, antimony and fluorine; the indium oxide film is formed directly on the glass substrate and has a refractive index lower than 0.4 and an extinction coefficient higher than 0.4; and the tin oxide film has a film thickness of more than 35 nm but 150 nm or less.
Patent CA-3016160-A1 (CA)
Inventor: FOSAAEN KEN ERVIN
IPC: G01N27/407
Filed: 2017-03-08
Abstract: Nitrous oxide (NOx) sensors and related methods and systems for use with combustion processes.  The NOx sensor uses metal oxide semiconductors. The NOx sensor may have two sensing circuits that share a common electrode. The sensing circuits are differentiated by having different porous catalytic filter coatings protecting the metal oxide semiconductors: one sensing circuit has a porous catalytic filter coating that contains a Noxcat material (rhodium, ruthenium, cobalt, palladium, or nickel), while the porous catalytic filter coating of the other sensing circuit is substantially free of Noxcat material. The two sensing circuits are simultaneously exposed to the exhaust gases at a common macro location. The NOx level may be determined based on a difference in resistance between the two sensing circuits and a temperature of the NOx sensor.
Patent CA-3016512-A1 (CA)
Inventor: FUKUYAMA YOSUKE
IPC: H01M8/2485
Filed: 2016-10-18
Abstract: With this manufacturing method, a layered body in which a plurality of fuel cell unit cells are layered is heated to manufacture a fuel cell stack. The fuel cell unit cell comprises an inorganic sealing material that contains an organic substance, a separator, an anode electrode, an electrolyte, and a cathode electrode. An oxygen-containing gas is supplied to a fuel flow channel near the anode electrode, and heating is carried out while current is applied from the exterior so that a charge moves from the anode electrode side to the cathode electrode side to remove the organic substance in the inorganic sealing material that contains an organic substance.
Patent CA-3016875-A1 (CA)
Title: Derive de 3-desoxy et compositions pharmaceutiques associees
Inventor: PELLICCIARI ROBERTO
IPC: C07J9/00
Filed: 2017-03-07
Abstract: La présente invention concerne le composé 1 : ou un sel ou un conjugué d'acide aminé pharmaceutiquement acceptable de celui-ci. La présente invention concerne un activateur de FXR et des procédés de production et d'utilisation dudit composé.