baber/WOPTO huggingface dataset:
Patent AU-7451198-A (AU)
Title: Solid pharmaceutical preparation
Inventor: SHIMIZU TOSHIHIRO
IPC: A61K9/20
Filed: 1998-05-26
Abstract: A solid preparation which comprises (i) a pharmaceutically active ingredient, (ii) one or more water-soluble sugar alcohols selected from the group consisting of sorbitol, maltitol, reduced starch saccharide, xylitol, reduced palatinose and erythritol, and (iii) low-substituted hydroxypropylcellulose having hydroxypropoxyl group contents of 7.0 to 9.9 percent by weight; which exhibits excellent buccal disintegration and dissolution and also appropriate strength.
Patent AU-7482087-A (AU)
Title: Process for the production of aldehydes by hydroformylation
Inventor: HARRISON GEORGE EDWIN
IPC: C07C45/00
Filed: 1987-06-12
Abstract: PCT No. PCT/GB87/00408 Sec. 371 Date Nov. 21, 1988 Sec. 102(e) Date Nov. 21, 1988 PCT Filed Jun. 12, 1987 PCT Pub. No. WO88/00179 PCT Pub. Date Jan. 14, 1988.Continuous process for hydroformylation of olefins containing, typically, from 6 to 20 carbon atoms to produce the corresponding aldehydes. The rate of formation of high boiling aldehyde condensation products is minimized by use of a high boiling inert solvent whose boiling point, at the pressure prevailing in the product recovery zone, lies intermediate between that of the highest boiling aldehyde product produced in the hydroformylation reaction and that of the ligand, as well as by maintaining the concentration of product aldehyde at or below a predetermined minor amount. In this way the length of a production run can be significantly extended before it becomes necessary to shut down the plant due to accumulation of high boiling aldehyde condensation products.
Patent AU-7509781-A (AU)
Title: Dispersion mixer
Inventor: BURGESS BASIL ARTHUR
IPC: B01F7/30
Filed: 1981-09-09
Abstract: A dispersion mixer is disclosed for breaking up and dispersing agglomerated particles in a liquid medium. The mixer has the capability of causing high speed particles to strike each other in such a manner as to develop their maximum shear energy potential and thus be more efficient than existing dispersion mixers. The mixer operates in a container and has a first rotor shaft extending downwards at the approximate center of the container, a second rotor shaft substantially parallel to the first rotor shaft, spaced from the first rotor shaft, at least one mixing rotor disc mounted on the first rotor shaft, and at least one mixing rotor disc mounted on the second rotor shaft, a first drive for rotating the first rotor shaft about its own axis, and the second rotor shaft about its own axis, and a second drive for moving the second rotor shaft in a circumferential path about the first rotor shaft.
Patent AU-7511600-A (AU)
Title: Oral dosage forms
Inventor: BARTHOLOMAUS JOHANNES
IPC: C07C217/74
Filed: 2000-08-29
Abstract: A controlled-release oral dosage formulation of a salt-forming active ingredient, wherein the active ingredient is present as at least two different salts in a solid aggregation state, wherein the two different salts have different water solubility and release the active ingredient in-vitro at different release rates, provided that oral dosage formulations are excluded which comprise a resin carrying a sulfonate group and a resin carrying a carboxyl group and which contain an active ingredient in a form fixed to these resins.
Patent AU-7545694-A (AU)
Title: Cast bone ingrowth surface
Inventor: SCHWARTZ MELVIN M
IPC: A61F2/28
Filed: 1994-09-21
Abstract: An orthopaedic implant comprising a cast metal base member having an outer surface and an ingrowth surface comprising a plurality of attachment spacer elements of unequal lengths integrally cast with said base member and a metal attachment element integrally cast with said spacer elements, said attachment element having connecting elements extending between said spacer elements to allow attachment of the bone to occur between an underside of said connecting elements and the outer surface of said base member. The invention also consists of a method for preparing such an implant, wherein the spacer elements are of equal or unequal length, which comprises inserting a preformed ceramic pattern for the ingrowth surface into a die for the implant, injecting a meltable material in its molten state into the die at a temperature below the melting temperature of the ceramic to fill the holes and grooves of the pattern. The insert, partially encapsulated with the meltable material, is coated with additional ceramic material and the meltable material removed after melting to form a ceramic mold for the implant containing the ingrowth surface pattern. An alternative method for preparing a ceramic mold for the above-indicated orthopedic implant is to form the mold containing the ceramic insert by incrementally laying down the layers thereof under computer control.
Patent AU-7637001-A (AU)
Title: Process for the preparation of pesticidal compounds
Inventor: ROUSSEAU JEAN-FRANCOIS
IPC: C07D231/44
Filed: 2001-06-07
Abstract: A process for the preparation of a compound of general formula (I), wherein R<SUP>1 </SUP>is CN or CSNH<SUB>2</SUB>; R<SUP>2 </SUP>is hydrogen or chloride; and R<SUP>3 </SUP>is halogen or haloalkyl or haloalkoxy or SF<SUB>5 </SUB>which process comprises reacting a compound of formula (II), where R<SUP>1</SUP>, R<SUP>2 </SUP>and R<SUP>3 </SUP>are as defined above; with a proton source.
Patent AU-7907900-A (AU)
Title: Method and device for producing machine components that are provided with at least one sliding surface
Inventor: MOCZULSKI LECH
IPC: C23C4/12
Filed: 2000-09-27
Abstract: The invention relates to the production of machine components, especially piston rings (3) and/or pistons and/or cylinder liners of engines, preferably two-stroke great diesel engines, that are provided with at least one sliding surfaces. Said engines are provided with a coating (4) in the area of the sliding surface thereof. The coating comprises an aluminium bronze and is applied to the base material. The aim of the invention is to provide the properties of the coating, compared with a coating consisting of pure aluminium bronze, in any desired way. The coating (4) is produced by aggregating aluminium bronze and at least one additional material that is not alloyed therewith. The coating (4) is sprayed onto the base material in one or several layers according to the thermo spray method.
Patent AU-7941298-A (AU)
Title: Box
Inventor: COLLENBURG GEORGE ANTHONIE VAN
IPC: B65D5/42
Filed: 1998-06-16
Abstract: Box consisting of: a) a bottom wall (10), b) a top wall (12) at a distance from and parallel to the bottom wall, c) connecting to each other a front wall (14), a first side wall (16), a rear wall (18) and a second side wall (20), all between the bottom and top wall and at right angles thereto, provided with: d) an elongated fold-over segment (22) connecting to the transition between bottom wall (10) and front wall (14), and in succession divided by fold lines (26, 30) into: d1) a first fold-over wall (24) approximately the size of the front wall (14), d2) a second fold-over wall (21) approximately the size of the top wall (12), d3) a third fold-over wall (32) roximately the size of the bottom wall. A fourth fold-over wall approximately the size of the rear wall may be present between the second and third fold-over walls (78, 44A, 44B, 44C).
Patent AU-8287791-A (AU)
Title: Cancer-associated scm-recognition factor, preparation and method of use
Inventor: CERCEK BORIS
IPC: A61K47/48
Filed: 1991-06-18
Abstract: A cancer recognition factor (SCM factor) useful in the performance of the structuredness of the cytoplasmic matrix (SCM) test has been isolated, purified to substantial homogeneity, and characterized, and methods for its use have been described. The factor is a peptide of at least 9 amino acid residues including a core sequence of 9 amino acid residues having an amphipathicity profile substantially equivalent to that of the sequence F-L-M-I-D-Q-N-T-K and produces at least a 10 percent decrease in the intracellular fluorescence polarization value of SCM-responding lymphocytes from donors afflicted with cancer. A synthetic SCM factor representing a consensus sequence of M-I-P-P-E-V-K-F-N-K-P-F-V-F-L-M-I-D-Q-N-T-K-V-P-L-F-M-G-K is fully active. Antibodies specific for SCM factor are useful in immunoassays that can detect the factor, including detection in cancer cells grown in vitro. The SCM factor is useful for screening of blood samples and other body fluids or cell aspirates for the presence of malignancy in the donor. The multiple action spectrum of the SCM factor including cancer proliferation and invasion promotion, as well as inhibition of the host's immune defense mechanisms and synthesis of SCM factor by cancer cells, represents a novel target for cancer management. Methods for reducing in vivo activity of the SCM factor, such as dialysis or antibody neutralization, can also be useful in the management of cancer.
Patent AU-8749598-A (AU)
Title: Biarylalkylenecarbamic acid derivatives and bacteriocides for agricultural an d horticultural use
Inventor: IKEGAYA KAZUHIRO
IPC: C07C271/22
Filed: 1998-08-24
Abstract: Biarylalkylenecarbamic acid derivative represented by general formula (I): <CHEM> Äwherein Q is a phenyl group which may be substituted or the like, X is a halogen atom, a (C1-C6) alkyl group or the like, n is 0 or an integer of from 1 to 4, R<1> is a (C1-C6) alkyl group or the like, R<2> is a hydrogen atom, a (C1-C6) alkyl group or the like, A is a (C1-C7) alkylene group which may be branched, and G is an oxygen atom, a sulfur atom or a group -NR<3>- (wherein R<3> is a hydrogen atom or a (C1-C4) alkyl group)Ü and agricultural and horticultural fungicides. The agricultural and horticultural fungicides of the present invention are useful as agricultural and horticultural fungicides because they have high preventive effects on cucumber downy mildew, apple scab, wheat powdery mildew, rice blast, cucumber gray mold and rice sheath blight without damaging crops, and are excellent in residual effectiveness and rain-resistance.
Patent AU-9671498-A (AU)
Title: Gene therapy approaches to supply apolipoprotein a-i agonists and their use to treat dyslipidemic disorders
Inventor: DASSEUX JEAN-LOUIS
IPC: A61K48/00
Filed: 1998-09-28
Abstract: The invention relates to genetic approaches to supply nucleotide sequences encoding modified forms of the native forms of apolipoprotein A-I (ApoA-I): mature ApoA-I, reproApoA-I and proApoA-I; including native ApoA-I modified to contain ApoA-I agonists, peptides which mimic the activity of ApoA-I; ApoA-I superagonists, peptides which exceed the activity of native ApoA-I; and modified native ApoA-I having one or more amphipathic helices replaced by the nucleotide sequences of one or more ApoA-I agonists; for the treatment of disorders associated with dyslipoproteinemia, including cardiovascular disease, atherosclerosis, restenosis, hyperlipidemia, and other disorders such as septic shock.
Patent AU-9736898-A (AU)
Title: Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors
Inventor: PETERS DAN
IPC: C07D417/04
Filed: 1998-10-27
Abstract: Heteroaryl diazacycloalkane derivatives (I) are new. Heteroaryl diazacycloalkane derivatives of formula (I) and their enantiomers or mixtures, isotopes and salts are new. [Image] n : 1-3 m : 0-2; R : H, alkyl, cycloalkyl, cycloalkylalkyl or aralkyl; R 1>aminophenyl; nitrophenyl; hydroxyphenyl; alkoxyphenyl; monocyclic 5-6 membered heterocyclyl (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino, NO 2, COOR 3, CONR 2R 3, NHCO 2R 2and/or OCONR 2R 3); aryl (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino and/or NO 2); X-alkyl-Y-alkyl (optionally alkyl substituted by alkoxy or thioalkoxy); X-(alkyl) o-aryl (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylene-dioxy, halo, CF 3, OCF 3, CN, amino and/or NO 2); X-(alkyl) o-Z (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino and/or NO 2), monocyclic 5-6 membered heterocyclyl (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino and/or NO 2) (sic), bicyclic heterocyclyl comprising a 5-6 membered monocyclic heterocyclyl fused to a benzene ring (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, alkoxy-alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino, NO 2, aryl optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amine and/or NO 2) or monocyclic 5-6 membered heterocyclyl (optionally substituted by alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, cycloalkoxy, alkenoxy, alkynoxy, methylenedioxy, halo, CF 3, OCF 3, CN, amino and/or NO 2); X, Y : O, S or NH, N-alkyl or Se; o : 0 or 1 and Z : 5-6 membered monocyclic heterocyclyl. ACTIVITY : Analgesic; Neuroprotective; Nootropic; Tranquilizer; Antiinflammatory; Antiaddictive; Antismoking; Anticonvulsant; Neuroleptic; Antidepressant; Antiasthmatic; Antianginal; Antimigraine. The affinity of 1-(6-chloro-5-methoxy-3-pyridyl)-homopiperazine fumaric acid salt for nicotinic Ach receptors was investigated in a test for in vitroinhibition of 3H-cytisine binding. The compound exhibited and IC 50value of 0.0007 mu M. MECHANISM OF ACTION : Nicotinic acetyl choline receptor ligand.
Patent BE-896861-A (BE)
Title: Pressure conversion in variable volume chamber
IPC: F03D1/04
Filed: 1983-05-27
Abstract: No further information has been published for this application.
Patent BE-898998-A (BE)
Title: Projectile a empennage stabilisateur et cage de propulsion
IPC: F42B10/14
Filed: 1984-02-24
Abstract: Un projectile (1) à vol stabilisé par les ailes d'un empennage rabattable est enveloppé d'une cage de propulsion (2) composée d'une pluralité de segments (5). La partie arrière de cette cage de propulsion (2) recouvre au moins partiellement les ailes (10) de l'empennage rabattable et les bloque ainsi dans leur position rabattue. Les ailes (10) facilitent la libération de la cage de propulsion (2) du projectile après la sortie de ce dernier du canon de l'arme.
Patent BE-750010-A (BE)
Title: Building material containing a phenol/alde- - hyde polymer
Inventor: GREGOR A
IPC: E04C2/24
Filed: 1970-05-06
Abstract: Material comprises 90 to 99% wt. of a mineral pref. sand of particle size below 3 mm. more pref. below 1 mm. preferably a mixture of different sized particles, and 10 - 1% wt. of a phenol/aldehyde resin, e.g. of a cresol and an acetaldehyde, butyraldehyde or furfural, optionally there is present as reinforcement mineral asbestos, glass synthetic or vegetable fibres, or metal bars, fibres or mats.
Patent BE-792204-A (BE)
Title: Low inertia displacement mechanism - for inertia welding appts electrode holders
Inventor: BURBURE S DE
IPC: B23K11/02
Abstract: A low inertia displacement mechanism, esp. for inertia welding appts electrode holders has two relatively mobile parts (I) (II) and >=1 elastic membrane which is fixed by its edges to (I) and between its edges to (II) (I) partially encloses (II). The arrangement reduces the mass of the moving parts to the min. possible to improve weld quality.
Patent BG-97982-A (BG)
Title: Inprovements of benzothiophenes or compounds bound to them
Inventor: BLACK LARRY J
IPC: A61K31/425
Filed: 1993-07-22
Abstract: The use of raloxifene, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for preventing or treating osteoporosis in a postmenopausal woman.
Patent BR-0000152-A (BR)
Title: Aparelho sensor de torque para um sistema de direção assistido, e conjunto sensor
Inventor: MILLER JOSEPH D
IPC: B62D6/10
Filed: 2000-01-24
Abstract: "APARELHO SENSOR DE TORQUE PARA UM SISTEMA DE DIREçãO ASSISTIDO, E, CONJUNTO SENSOR". Um aparelho sensor de torque (30) inclui primeiros e segundos elementos sensores (62, 70; 66, 74) que são substancialmente diametralmente opostos em relação a um eixo central que se estende entre os primeiros e segundos elementos sensores. Cada um dos elementos sensores (62, 70; 66, 74) é operativo para prover um sinal elétrico (34) que varia como uma função da posição relativa entre primeiras e segundas partes dos respectivos elementos sensores. Os sinais elétricos (34) dos primeiros e segundos elementos sensores (62, 70; 66, 74) variam em relação inversa em resposta a movimento relativo não rotacional entre as primeiras e segundas partes dos respectivos elementos sensores.
Patent BR-0005491-A (BR)
Title: Sistema de sangria para um conjunto de eixo e cubo
Inventor: SITTER DON
IPC: B60B35/00
Filed: 2000-11-21
Abstract: <B>SISTEMA DE SANGRIA PARA UM CONJUNTO DE EIXO E CUBO<D> Um sistema de sangria para um cubo de roda compreendendo um primeiro suspiro filtrado na cavidade extrema de roda e um segundo suspiro formado por uma válvula de alívio de pressão, de um sentido sangrando o tubo de eixo para a atmosfera. O sistema de sangria define uma trajetória de sangria da cavidade extrema de roda través de um primeiro suspiro preferivelmente filtrado para dentro do tubo de eixo a seguir através de uma segunda válvula de retenção conectanto o tubo de eixo à atmosfera. Um material poroso é posicionado para cobrir a passagem de sangria na cavidade extrema da roda para permitir que um fluxo de gases entre e saia da passagem de sangria enquanto evita que líquidos e outros contaminantes se desloquem através da mesma. O material poroso é mantido no lugar sobre o suspiro por um anel de encaixe ou outro meio de retenção adequado disposto no interior do elemento de bujão sangrado. O segundo suspiro de tubo de eixo é disposto ao longo do tubo de eixo para sangrar o próprio tubo para a atmosfera com alívio de pressão.
Patent BR-0007473-A (BR)
Title: Composições tendo estabilidade melhorada
Inventor: DOBROZSI DOUGLAS JOSEPH
IPC: A61K47/14
Filed: 2000-01-10
Abstract: Patente de invenção: <B>COMPOSIçõES TENDO ESTABILIDADE MELHORADA''<D>. A presente invenção refere-se a composições líquidas tendo liberação melhorada de ativos farmacêuticos. Estas composições compreendem ativos farmacêuticos, solvente e um agente de redução. Estas composições podem tomar a forma de elixires líquidos colocados na boca por pastilhas cheias de líquido, dispositivos de dosagem de líquido medido, atomizadores e cápsulas comestíveis de liberação de líquido.
Patent BR-0010251-A (BR)
Title: Disco de vedação e compósito de pelìcula para o fechamento de um recipiente
Inventor: WIENING HEINZ-RULDOF
IPC: B65D77/20
Filed: 2000-05-03
Abstract: Patente de Invenção: DISCO DE VEDAçãO E COMPóSITO DE PELìCULA PARA O FECHAMENTO DE UM RECIPIENTE". A invenção refere-se a um compósito de película, que serve como um fechamento para uso com um recipiente (10) que tem uma abertura (11) que é delimitada por uma borda periférica. Compósito de película (30) compreende diversas camadas. Uma camada adesiva (32) é disposta entre as duas camadas de topo (31, 33) pelo menos sobre uma superfície parcial. A camada mais superior (33) compreende uma dobra que se projeta para cima (40).
Patent BR-0012283-A (BR)
Inventor: STEWART A FRANCIS
IPC: C12Q1/68
Filed: 2000-07-10
Abstract: The present invention is directed to methods and compositions for DNA subcloning using bacterial recombinase-mediated homologous recombination. The invention relates to methods for cloning, compositions comprising polynucleotides usefall as cloning vectors, cells comprising such polynucleotide compositions, and kits useful for cloning mediated by bacterial recombinases, such as RecE/T and Redalpha/beta.
Patent BR-0014972-A (BR)
Title: Aminoacidos bicìclicos como agentes farmacêuticos
Inventor: BRYANS JUSTIN STEPHEN
IPC: A61K31/00
Filed: 2000-10-17
Abstract: "AMINOáCIDOS BICìCLICOS COMO AGENTES FARMACêUTICOS". Os compostos da presente invenção são aminoácidos bicíclicos úteis no tratamento da epilepsia, dos ataques de desmaio, da hipoquinesia, dos distúrbios cranianos, dos distúrbios neurodegenerativos, da depressão, da ansiedade, do pânico, da dor, da artrite, dos distúrbios neuropatológicos e dos distúrbios no sono. São incluídos os processos para a preparação dos produtos finais e dos intermediários úteis no processo. São também incluídas as composições farmacêuticas contendo um ou mais dos compostos.
Patent BR-0016657-A (BR)
Title: Método para liberar um agente de benefìcio a uma área selecionada de um tecido para exercer uma atividade pré-determinada, e, dispositivo para uso no mesmo
Inventor: HEMMINGTON SANDRA
IPC: D06L4/40
Filed: 2000-12-08
Abstract: "MéTODO PARA LIBERAR UM AGENTE DE BENEFìCIO A UMA áREA SELECIONADA DE UM TECIDO PARA EXERCER UMA ATIVIDADE PRé-DETERMINADA, E, DISPOSITIVO PARA USO NO MESMO". Provê-se um método para liberar um agente de benefício a uma área selecionada de um tecido para exercer uma atividade pré-determinada, em que a área é pré-tratada com uma molécula de ligação multi-específica que tem uma alta afinidade de ligação para referida área através de uma especificidade e é capaz de ligar ao referido agente de benefício através de outra especificidade., seguido por contato da referida área pré-tratada com referido agente de benefício, para melhorar referida atividade pré-determinada à referida área. Preferivelmente, a molécula de ligação é um anticorpo ou fragmento do mesmo, ou uma proteína de fusão compreendendo um domínio de ligação de celulose e um domínio tendo uma alta afinidade de ligação para outro ligando que é dirigido para referido agente de benefício. O método é utilizável para remoção de manchas, liberação de perfume, e tratamento de colarinhos e punhos em roupas. Também é provido um dispositivo para uso neste método, que é um distribuidor capaz de depositar molécula de ligação multi-específica a uma área selecionada de um tecido através de uma cera semi-sólida ou bastão de sabão, pulverização, aerossol, escova impregnada, gel ou espuma e semelhantes.
Patent BR-0016726-A (BR)
Inventor: WOBBEN ALOYS
IPC: F03D1/06
Filed: 2000-12-19
Abstract: The invention concerns a rotor blade for a wind power installation. The degree of efficiency of rotor blades is determined by the afflux angle, that is to say the angle between the rotor blade profile chord and the afflux direction of the air. Particularly in the case of wind power installations the afflux angle depends on the rotor blade speed-that is to say the speed of rotation of the rotor-and the wind direction: the afflux direction is distinguished by the sum vector of the wind speed v<SUB>Wind </SUB>and the speed of the rotor blade tip v<SUB>Tip</SUB>, the effective afflux speed v<SUB>eff</SUB>, see FIG. 1, <?in-line-formulae description="In-line Formulae" end="lead"?>v<SUB>eff</SUB>=√{square root over (<SUB>Wind</SUB><SUP>2</SUP>)}+v<SUB>Tip</SUB><SUP>2</SUP> (1)<?in-line-formulae description="In-line Formulae" end="tail"?> The object of the invention is therefore that of reducing the sensitivity of a rotor blade to turbulent wind flows. A rotor blade for a wind power installation which is divided in its longitudinal direction into at least two portions which are integrally connected together and which are designed for different high-speed indexes, wherein the high-speed index, associated with the maximum power coefficient, of the portion which is further away from the rotor blade root is greater than the high-speed index, associated with the maximum power coefficient, of the portion respectively disposed closer to the rotor blade root.