baber/WOPTO huggingface dataset:
Patent CA-2300191-A1 (CA)
Inventor: BERNOT ALAIN
IPC: C12N15/12
Filed: 1998-08-13
Abstract: The invention concerns novel nucleic acids, in particular the gene responsible for Familial Mediterranean Fever (FMF), and the corresponding protein. It further concerns probes and primers for detecting and amplifying said gene, and kits and methods for detecting FMF. It also concerns all use of the gene and the protein, in particular for therapeutic purposes.
Patent CA-2301230-A1 (CA)
Title: Matrices chimiques combinatoires spatialement adressables en format cdrom
Inventor: DEMERS JAMES P
IPC: C12Q1/6874
Filed: 1997-09-19
Abstract: La présente invention concerne un procédé permettant de réaliser par synthèse photodirigée de très grandes matrices, spatialement adressables, de composés chimiques. En l'occurrence, la lumière est fournie par un laser, et les composés chimiques sont matricés en format CDROM sur un disque en rotation. L'invention concerne également une technique permettant de tester, avec un mécanisme pour CDROM, la matrice obtenue.
Patent CA-2302055-A1 (CA)
Title: Method of repairing cabled revetment blocks
Inventor: SMITH LEE A
IPC: E02B3/12
Filed: 2000-03-23
Abstract: A,method for installing and replacing revetment blocks in a cabled matrix. Each revetment block has a large opening therein for access to the cables that pass therethrough. The cable of a broken block is severed in the opening, and the parts of the broken block are removed. The ends of the severed cable are threaded through a replacement revetment block, and the block is lowered into place in conjunction with the neighboring blocks. The ends of the severed cable are pulled into the opening in the block and spliced together, preferably using a ferrule that is crimped to the ends of the severed cable. The large opening in each block also facilitates threading the cables through the rows of blocks in a matrix.
Patent CA-2302414-A1 (CA)
Inventor: BURDINSKI GERHARD
IPC: C07K16/00
Filed: 1998-09-21
Abstract: L'invention concerne un nucléoside de pentopyranosyle de la formule (I) ou de la formule (II), sa préparation et son utilisation pour préparer un agent thérapeutique, un agent diagnostique et/ou pour produire un composant électronique.
Patent CA-2305586-A1 (CA)
Title: Positioning system for digital telephone networks
Inventor: DUFFETT-SMITH PETER JAMES
IPC: H04W64/00
Filed: 1998-10-21
Abstract: The invention relates to determining the position of a mobile receiver (4) in a digital telephone network positioning system. A first receiver (3) is at a known location and others are mobile. The method involves transmitting signals from a plurality of sources (1), the transmission signals having a format at least a portion of which has predetermined values or a portion of which is repeated. The time offset of the transmission signals received at each receiver (4, 5) from a transmission source (1) relative to a reference clock of each receiver is determined by generating a reference signal locked to the reference clock. The reference signal has a similar format to the transmission signals and includes a portion identical to the predetermined values or repeated portion of the received signal and compares the received transmission signal and the reference signal. The time delay between the respective signals received at the receivers (4, 5) is determined from their relative time offset, to thereby determine the position of the other receivers (4).
Patent CA-2306033-A1 (CA)
Title: Header assembly for mounting to a circuit substrate
Inventor: RAISTRICK ALAN
IPC: H01R12/50
Filed: 2000-04-18
Abstract: A header assembly is mounted to a backplane and receives a complementary electrical connector. The header assembly has an insulating shroud having a base with backplane and connector sides and a primary edge, and differential signal pin pairs, ground shields, and ground pins mounted to the base. The signal pin pairs are arranged into rows extending in a first direction along the base and along the base primary edge, and columns extending in a perpendicular second direction along the base. The signal pins in each pair are adjacently arranged into a sub-row extending in the first direction. Each signal pin in a pair has an inner side facing the other pin in the pair, an opposing outer side, and primary and non-primary sides facing toward and away from the base primary edge, respectively. One ground shield is associated with each signal pin.  Each ground shield extends through the base between the connector side and the backplane side, and includes first and second attached wings arranged at right angles.  The first wing extends along the first direction adjacent and along either the primary or non-primary side of the associated signal pin, and the second wing extends along the second direction adjacent and along the outer side of the associated signal pin. The ground shields in combination substantially electromagnetically isolate within the base each signal pin pair from all others. Each ground pin electrically contacts at least one ground shield at the second wing thereof.
Patent CA-2306932-A1 (CA)
Title: Method and apparatus for implementing seamless playback of continuous media feeds
Inventor: PAWSON DAVID J
IPC: G11B27/031
Filed: 1998-10-19
Abstract: A method and system for storing a continuous feed of video is provided. According to one aspect of the invention, the continuous feed is encoded in a digital video format to produce a digital data stream. A series of content files is created by repeatedly performing the steps of (1) storing the digital data stream in a current file, and (2) establishing a new file as the current file when the current file satisfies a predetermined condition. If the series of content files contains more than a predetermined amount of the continuous feed, the oldest content file in the series of content files is deleted. Tag information that indicates information about frames contained in the digital data stream is generated. The tag information includes timestamps that indicate timing of frames relative to a beginning of the digital data stream. An initial time value that indicates an absolute time that corresponds to the beginning of the digital data stream. When a request from a client for playback beginning at a specified absolute time is received, the initial time value is subtracted from the specified absolute time to determine a relative time. The tag information is used to identify a location in the digital data stream that corresponds to the relative time. The digital data stream is then transmitted to the client beginning at the location in the digital data stream that corresponds to the relative time.
Patent CA-2308940-A1 (CA)
Title: Heat generator and design method thereof
Inventor: NIWA MASAMI
IPC: F24J3/00
Filed: 2000-05-19
Abstract: A heat generator comprises a partitioning wall 34 in opposed relation to a rotor in a heat generating area, in which the partitioning wall is formed with a supply groove 38 for introducing the viscous fluid to the outer peripheral area of the heat generating area from a storage area, and a recovery groove 39 for leading out the viscous fluid to the storage area from the outer peripheral area of the heat generating area. The shape, position and the mounting angle of the supply groove 38 and the recovery groove 39 are designed to set the outflow ratio a to not more than 0.92. The outflow ratio a is defined as the ratio (.alpha. = Qout1/Qin) of the amount Qout1 of the viscous fluid flowing out from the heat generating area due to the forcible transfer function of the recovery groove 39 to the total amount Qin of the viscous fluid flowing from the storage area into the heat generating area.
Patent CA-2313052-A1 (CA)
Inventor: LOPEZ MIGUEL MOTA
IPC: B60S1/48
Filed: 1998-11-19
Abstract: The present invention concerns a pump arrangement, in particular for wind-screen washer systems of motor vehicles. The pump housing (30) includes a liquid inlet (36), and a liquid outlet (38) through which the impeller (32) delivers the liquid (5) to be delivered out of the pump housing (30). Further, a sensor housing (40) is provided which is connected to the pump housing (30) and comprises a sensor arrangement (42, 42') responding to a changing liquid level (H, L) in the sensor housing (40). The sensor housing (40) has a liquid inlet (44) and a liquid outlet (46). According tothe claimed invention, the liquid outlet (46) of the sensor housing (40) and the liquid inlet (36) of the pump housing (30) are co-axially arranged with respect to each other.
Patent CA-2316878-A1 (CA)
Title: Hydrogen-free regeneration of dithiophosphorus metal extractants
Inventor: PERRAUD JEAN-JACQUES ROBERT
IPC: C07F9/02
Filed: 1999-08-11
Abstract: This is a method of regenerating dithiophosphorus acids from disulfides containing sulfur-sulfur bonds, formed by oxidation of dithiophosphorus acids, such as sulfur-sulfur bonding of dithiophosphoric, dithiophosphonic and dithiophosphinic acids, in a solvent extraction organic phase in which the dithiophosphorus acid is dissolved in a diluent. This process reacts metal directly with the organic solution containing the disulfide to produce a metal loaded complex form of the regenerated dithiophosphorus extractant in the organic solution. This metal complex forms by direct reaction of the metal with the disulfides without requiring the presence or the formation of nascent or gaseous hydrogen. The organic solution containing the regenerated dithiophosphorus extractant can be either directly recycled into a solvent extraction circuit or recycled after the loaded metal is stripped.
Patent CA-2319437-A1 (CA)
Title: Methods and reagents for decreasing allergic reactions
Inventor: SAMPSON HUGH A
IPC: C12N1/19
Filed: 1999-01-29
Abstract: It has been determined that allergens, which are characterized by both humoral (IgE) and cellular (T cell) binding sites, can be modified to be less allergenic by modifying the IgE binding sites. The IgE  binding sites can be converted to non-IgE binding sites by masking the site with a compound that prevents IgE binding or by altering as little as a single amino acid within the protein, most typically a hydrophobic residue towards the center of the IgE-binding epitope, to eliminate IgE binding. The method allows the protein to be altered as minimally as possible, other than within the IgE-binding sites, while retaining the ability of the protein to activate T cells, and, in some embodiments by not significantly altering or decreasing IgG binding capacity. The examples use peanut allergens to demonstrate alteration of IgE binding sites. The critical amino acids within each of the IgE binding epitopes of the peanut protein that are important to immunoglobulin binding have been determined. Substitution of even a single amino acid within each of the epitopes led to loss of IgE  binding. Although the epitopes shared no common amino acid sequence motif, the hydrophobic residues located in the center of the epitope appeared to be most critical to IgE binding.
Patent CA-2319828-A1 (CA)
Title: High density arrays for proteome analysis and methods and compositions therefor
Inventor: HUMPHERY-SMITH IAN
IPC: C40B60/14
Filed: 1999-01-29
Abstract: The present invention provides high-density arrays comprising a primary protein array and a secondary antibody array, wherein the secondary array comprises monoclonal antibodies and/or antibody variants or derivatives that bind specifically or non-specifically to one or more proteins in the primary array, and wherein the secondary array is used to determine the protein profile of a cell, tissue, organ or whole organism or a cellular extract, lysate or protein fraction derived therefrom. Also provided are methods of determining the epitope profile of cells, tissues, organs and whole organisms and cellular extracts, lysates or protein fractions derived therefrom, using the high density protein arrays of the invention, in particular in relation to diagnostic and therapeutic applications. The invention further provides for the enrichment of native proteins from complex mixtures of cellular proteins by employing one or more antibodies uniquely recognising an antigen of interest as defined by recognition patterns obtained when screening secondary antibody arrays against primary antigen arrays. In addition, one or more antibodies can be employed to produce a unique tag for target antigens and is employed to follow the expression levels of complex mixtures of cellular proteins and is conducted independently of the separation sciences. A similar approach is employed to produce a fingerprint of a biological sample, based upon recognition of a multiplicity of individual antigens providing a pattern useful in recognition or diagnosis of a group of biological samples of interest in healthy and diseased samples, or test and control experimental situations for diagnostic purposes.
Patent CA-2319884-A1 (CA)
Title: Pneumatic support column for a chair
Inventor: MILES GEORGE A
IPC: A47C5/02
Filed: 1993-06-15
Abstract: A tiltable chair including a base member (44), a seat (32), a back (34), and a linkage assembly (40) adapted to allow the seat and back to tilt downwardly and rearwardly and to allow pivotal movement of the seat about a pivot axis (52) in substantial alignment with the hip joints of a user. Other aspects of the invention are to provide a vertically adjustable column (42) for supporting the seat of the chair, a support assembly including a frame member (33) having a central opening therethrough and a receptacle formed around the perimeter thereof, a carrier member adapted to fit inside the receptacle, and a membrane of elastic material (210) covering the central opening, and a pair of armrests (36) adapted to be mounted to the chair to allow pivotal movement thereof.
Patent CA-2320241-A1 (CA)
Inventor: GRIFFIN JOHN H
IPC: A61K47/48
Filed: 1999-06-08
Abstract: La présente invention concerne des composés à base de macrolides, d'aminoglycosides, de lincosamides, d'oxazolidinones, de streptogramines, de tétracycline et/ou d'autres composés qui se lient à l'ARN ribosomique et/ou à une ou plusieurs protéines impliquées dans la synthèse des protéines ribosomiques de la bactérie. Ces composés conviennent au traitement d'infections bactériennes, car ils contrarient l'expression de protéines et ont une action antibactérienne. Les composés à liaisons multiples de l'invention contiennent de 1 à 10 ligands reliés par covalence à un ou plusieurs lieurs. Chaque ligand est un macrolide, un aminoglycoside, un lincosamide, un oxazolidinone, une streptogramine, de la tétracycline ou tout autre composé se liant à l'ARN ribosomique et/ou à une ou plusieurs protéines impliquées dans la synthèse des protéines ribosomiques de la bactérie.
Patent CA-2320486-A1 (CA)
Inventor: PALM BENGT
IPC: A23L3/22
Filed: 1999-02-05
Abstract: The invention relates to an apparatus in an infusor. The infusor is of the type which includes an autoclave with an inlet located in its upper region for the product which is to be heat-treated, and an outlet for the ready-treated product located in its lower region. The inlet is provided with a distributor chamber which divides the product into small droplets when the product enters into the autoclave. The infusor further includes an inlet for steam which is placed in the lower region of the autoclave. The steam inlet consists substantially of a concentric aperture in the casing surface of the autoclave.
Patent CA-2321010-A1 (CA)
Inventor: SCHULTHEIS BERND
IPC: H05K3/10
Filed: 2000-09-27
Abstract: A process for producing a printed electrical circuit or a hybrid circuit, wherein a print medium having particles with electric conductivity, or having ferromagnetic, piezoelectric, dielectric, electrochromic and/or electroluminescent properties, is printed on a substrate. This invention relates to a print medium for printing electrical circuits or a hybrid circuits having particles which are electrically conductive, or which have ferromagnetic, piezoelectric, dielectric, electrochromic and/or electroluminescent properties. In order to produce the circuits flexibly in a simple manner, the print medium of this invention is imprinted on the substrate in the form of a toner, either electrographically or electrostatically means. The print medium can be a toner which can be processed electrographically and which has charge control particles and carrier substances.
Patent CA-2323158-A1 (CA)
Title: Use of pkc inhibitors for the manufacture of a medicament for the treatment of cytomegalovirus infection
Inventor: WAYS DOUGLAS KIRK
IPC: A61K31/407
Filed: 1999-03-05
Abstract: A method for treating CMV infection and disease conditions associated therewith is disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-¢N,N'-1,1'-((2"-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)-butane)-bis-(3,3'-indoly1)!-1(H)-pyrrole-2,5-dione hydrochloride salt.
Patent CA-2323643-A1 (CA)
Title: System for producing data-containing data carriers
Inventor: BETHSCHEIDER GERHARD
IPC: G06Q30/00
Filed: 2000-10-18
Abstract: For the production of data-containing data carriers, data is transmitted from a database server (2) to a database client (3) via an asymmetrical transmission path (4), and the data carrier is produced by the database client.
Patent CA-2324677-A1 (CA)
Inventor: STEWART JAMES F
IPC: A01N57/20
Filed: 2000-10-26
Abstract: An agrochemical formulation aid, and a process for its preparation, comprising from about 135 to about 165 parts by weight mineral oil paraffinic distillate; from about 23 to about 29 parts by weight 2-octanol; from about 42 to about 52 parts by weight oleyl-cetyl alcohol; from about 46 to about 56 parts by weight polyoxyethylene(2)oleylether; from about 9 to about 11 parts by weight polyoxyethylene(8)nonylphenolethin; from about 1.2 to about 1.4 parts by weight sodium lauryl sulphate; from about 36 to about 43 parts by weight fatty alcohol alkoxylate; from about 7.5 to about 9.5 parts by weight plant terpenes; from about 610 to about 670 parts by weight of a mixture containing from about 0.8 to about 1.2 parts by weight of diammonium phosphate in 2.7 to 3.3 parts by weight water, and from about 2.2 to about 2.8%w/v tetrasodium ethylene diamine tetracetate; and from about 8 to about 22 parts by weight of cab-o-sil. By using this formulation aid, it is possible to convert an agrochemical, such as glyphosate directly on site into a sprayable aqueous system. This has the advantage of avoiding having to use pre-formulated products, and avoids the storage difficulties attendant upon pre-formulated products, such as the sensitivity of water containing emulsions to freezing.
Patent CA-2327501-A1 (CA)
Title: Technique et instrumentation pour arthrodese intersomatique du rachis
Inventor: BOYD LAWRENCE M
IPC: A61B19/00
Filed: 1999-04-09
Abstract: Technique et instrumentation convenant notamment pour préparer l'espace intervertébral par abord antérieur du rachis. Dans l'un des aspects de l'invention, un gabarit extensible (10) comporte des guides (26, 24) destinés à guider un élément coupant (601) afin de former des ouvertures bilatérales dans l'espace intervertébral. Dans un autre aspect, un élément guide amélioré (450) permet de guider un outil coupant. L'invention concerne également un manchon de guidage (100) amélioré à deux tubes, qui comporte une extension distractive centrale (116) et des extensions non distractives latérales (118, 120). Eventuellement, le manchon de guidage (100) comporte des fenêtres (110, 112) et un couvercle (160) destiné à recouvrir sélectivement lesdites fenêtres. Le manchon peut comporter également un trépan aléseur (200) amélioré, comprenant une chambre interne (209) et éventuellement un dispositif de couplage modulaire (254). Une butée de profondeur (326) permet de bloquer sélectivement un manche d'outil (360) et un manchon de guidage (370), de façon à commander la pénétration dudit outil dans l'espace intervertébral. L'invention concerne également une technique qui permet d'utiliser lesdits instruments.
Patent CA-2327584-A1 (CA)
Inventor: FODOR ERVIN
IPC: C12N15/09
Filed: 1999-05-06
Abstract: L'invention concerne un virus atténué de la grippe portant un segment d'acide nucléique génomique qui comprend des régions 5' et 3' non codantes constituant une région double mutée d'un segment génomique d'ARN de virus de la grippe, liée de manière opérationnelle à une séquence codant pour une protéine d'une protéine virale de la grippe, ou une modification fonctionnelle de celui-ci. Ladite région double comporte au moins une substitution de paire de bases telle que l'expression de ladite séquence codant pour une protéine dans des cellules infectées par ledit virus est réduite de manière à former un phénotype atténué. Le virus atténué de la grippe peut être utilisé dans un vaccin.
Patent CA-2329419-A1 (CA)
Title: Procede et appareil de correction d'erreurs
Inventor: RUBERG ALAN T
IPC: G06F13/00
Filed: 1999-04-20
Abstract: L'invention concerne un programme de correction d'erreurs utilisé dans un système informatique dans lequel les données sont fournies d'un service à un terminal. Ces données changent de manière dynamique, l'utilisateur étant plus intéressé par l'état final ou en cours de ces données que par les états intermédiaires de celles-ci. Les données sont fournies dans un flux de blocs, des numéros de "séquence" étant associés à chacun de ces blocs. Cette invention suppose donc que le fournisseur de données transmet des blocs de données en ordre de séquence. Le terminal recherche les numéros de séquence des blocs entrants, et s'il s'avère qu'un ou plusieurs blocs ont été sautés ou sont manquants, ce terminal demande à la source centrale des données mises à jour. Contrairement aux systèmes traditionnels, dans lesquels le(s) bloc(s) manquant(s) doivent être à nouveau envoyés, la présente invention permet aux informations contenues dans l'instruction manquante, par exemple les données en cours, de venir s'afficher dans la zone associé au bloc manquant. La source centrale gère l'état en cours des données dans toutes les zones d'affichage, et envoie un bloc de données contenant les données demandées. Dans le même temps, le terminal continue de recevoir et d'afficher tous les blocs de données reçus, sans attendre la mise à jour, ce qui différencie ce système des systèmes traditionnels, dans lesquels l'affichage s'interrompt jusqu'à réception des données de remplacement.
Patent CA-2329506-A1 (CA)
Title: Molecules du type alg-2lp, alg-2 et utilisations de ces dernieres
Inventor: CURTIS RORY A J
IPC: C07K14/47
Filed: 1999-05-13
Abstract: La présente invention porte sur des molécules d'acides nucléiques isolées, appelées molécules d'acide nucléique hALG-2LP, sALG-2LP, et mALG-2LP, qui codent des protéines impliquées dans la modulation de la mort cellulaire programmée; des molécules d'acide nucléique antisens, des vecteurs d'expression de recombinaison contenant les molécules d'acide nucléique hALG-2LP, sALG-2LP et mALG-2LP, des cellules hôtes dans lesquelles les vecteurs d'expression ont été introduits et des animaux transgéniques non humains dans lesquels un gène hALG-2LP, sALG-2LP ou mALG-2LP a été introduit ou interrompu; des protéines isolées hALG-2LP, sALG-2LP, et m ALG-2LP, des protéines de fusion, des peptides antigéniques et des anticorps anti-hALG-2LP, sALG-2LP et mALG-2LP; ainsi que sur des procédés de diagnostic dans lesquels on utilise les compositions de cette invention.
Patent CA-2330256-A1 (CA)
Title: Treatment of inflammatory bowel disease
Inventor: PFIRRMANN ROLF W
IPC: A61K31/00
Filed: 2001-01-05
Abstract: Patients suffering from inflammatory bowel disease such as Crohn's disease or ulcerative colitis are treated either orally or intravenously with methylol transfer agents, such as taurolidine and/or taurultam. These agents can be used in combination with other drugs thereby allowing the use of smaller amounts of the other drugs and limiting unwanted side effects.