baber/WOPTO huggingface dataset:
Patent AU-2017362946-A1 (AU)
Title: Non-unique barcodes in a genotyping assay
Inventor: SAUSEN MARK
IPC: G16B20/00
Filed: 2017-11-14
Abstract: The present disclosure involves ctDNA assays that interrogate many regions from a single sample with high precision and accuracy, while evaluating multiple forms of cancer-related genomic alterations including sequence mutations and structural alterations. The disclosure provides simplified yet robust methods that achieve high sensitivity and specificity by analyzing cancer genes using a limited pool of non-unique barcodes in combination with endogenous barcodes. Samples are captured and sequenced using high coverage next-generation sequencing to allow tumor-specific somatic mutations, amplifications, and translocations to be identified.
Patent AU-2017364484-A1 (AU)
Title: System and method for medical condition diagnosis, treatment and prognosis determination
Inventor: MCKINNON TOM CLARENCE
IPC: G06N5/00
Filed: 2017-11-28
Abstract: The apparatus and method disclosed relates to a system and method for identifying a medical condition in a patient. The system and method makes use of a remote terminal where tests and scans may be carried out and sent to a central server that receives patient medial data and detects anomalous characteristics in the tests and scans, and determines a diagnosis and probability of the diagnosis based on scans, tests presenting complaint and risk factors in the client medial history, lifestyle, or family medical history. Treatment and prognosis may also be determined in similar fashion. There is also provide an apparatus that simulates the effect of an ophthalmological condition on a virtual reality headset.
Patent AU-2017385611-A1 (AU)
Title: Method for generating higher order genome editing libraries
Inventor: KAULICH MANUEL
IPC: C12N15/10
Filed: 2017-12-27
Abstract: The present invention pertains to a novel method for the generation of highly diverse RNA expressing vectors and vector libraries for use in targeted gene knock out, knock down and genome modification approaches. The invention pertains to a method for generating such higher order libraries without the need of classical cloning technologies. This is particularly useful for libraries based on large vectors wherein a sequence cannot be easily mutated with classical mutagenesis methods. The vectors and libraries generated according to the methods of the invention are in particular for RNA assisted silencing technologies such as RNA interference, and for targeted genome editing using the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas system or similar RNA/DNA-encoded gene perturbation systems which use small guide RNAs to target the CRISPR complex to a specific genomic sequence. The invention provides also kits comprising the materials for performing the methods of the invention.
Patent WO-2018204982-A1 (WO)
Title: Dispositif de sécurité optique et procédé de fabrication
Inventor: JAMES RANDALL P
IPC: B41M3/14
Filed: 2018-05-11
Abstract: L'invention concerne un dispositif de sécurité comprenant un substrat et un ou plusieurs éléments de focalisation ou structures de lentille situés sur un côté du substrat. Le dispositif de sécurité comprend une pluralité d'éléments d'image associés à chaque élément de focalisation, les éléments d'image comprenant au moins des premier et second groupes d'éléments d'image. Chaque élément d'image peut être composé de pixels situés dans un plan d'objet à visualiser à travers l'élément de focalisation associé. Chaque élément d'image comprend un élément de réseau de diffraction ou un élément de réseau de sous-longueur d'onde qui, lorsqu'il est éclairé par une source de lumière, génère une image de diffraction observable à une plage d'angles de visualisation autour du dispositif. Les éléments d'image du premier groupe sont visibles dans une première plage d'angles de visualisation et les éléments d'image du second groupe sont visibles dans une seconde plage d'angles de visualisation. Le dispositif de sécurité est particulièrement approprié pour être utilisé sur des documents de sécurité, tels que des billets de banque. L'invention concerne également un procédé de formation d'un dispositif de sécurité.
Patent WO-2019060950-A1 (WO)
Title: Diagnostic test system and method
Inventor: HOPPER WILLIAM R
IPC: G01N33/50
Filed: 2018-09-21
Abstract: A diagnostic test system, including: a diagnostic test assembly and a diagnostic test apparatus to perform a test on a biological or environmental sample; the diagnostic test assembly includes: a sample preparation reservoir to receive the sample into a sample preparation fluid, such that a swab carrying the sample can be used to stir the preparation fluid and to wash the swab; a sample dispensing mechanism for insertion into the sample preparation reservoir; a closure to seal the sample preparation reservoir; at least one diagnostic test reservoir coupled to the sample preparation reservoir; and at least one seal between the sample preparation reservoir and the diagnostic test reservoir to prevent fluid movement between the respective reservoirs; wherein the sample dispensing mechanism is operable to disrupt the seal to allow sample fluid to enter the diagnostic test reservoir from the sample preparation reservoir, and to dispense a predetermined amount of fluid.
Patent WO-2019084608-A1 (WO)
Inventor: BURNS JAMES
IPC: A01N37/34
Filed: 2018-10-31
Abstract: La présente invention concerne de nouvelles particules de chlorothalonil enrobées de polymère, des procédés pour leur préparation, des compositions agricoles les contenant et des procédés pour les utiliser pour lutter contre ou empêcher l'infestation de plantes utiles par des microorganismes phytopathogènes.
Patent AU-2018200446-A1 (AU)
Title: Metered and active sprayer devices with aerosol functionality ("flairosol ii")
Inventor: MAAS WILHELMUS JOHANNES JOSEPH
IPC: B05B9/04
Filed: 2018-01-19
Abstract: In exemplary embodiments of the present invention, "Flairosol" dispensing devices can be provided. Such devices utilize a combination of Flair@ technology, pre compression valves and aerosol like pressurization of the dispensed liquid. Such a dispensing device has, for example, a main body comprising a pressure chamber, the latter being provided with a pressure piston and a pressure spring. The device further has a piston and a piston chamber which draws liquid from a container, for example, the inner container of a Flair@ bottle, and fills the pressure chamber with that liquid as a user operates a trigger in various compression and release strokes. The piston chamber has both an inlet valve and an outlet valve, which serve to prevent backflow. Liquid exiting the piston chamber under pressure (supplied by a user's pumping the trigger) enters a central vertical channel which is in fluid communication with both the pressure chamber (above the pressure piston) and a dome valve provided near the outlet channel at the top of the dispensing head. The dome valve has a preset pressure, such that once exceeded by the liquid, opens and allows for a spray. If the liquid pressure drops below such preset pressure the dome valve closes off the outlet channel, which serves to regulate the strength of the flow and preclude leakage. Alternatively, in an activated embodiment, for example, once the liquid is sufficiently pressurized, it can be dispensed by a user allowing the dome valve to open by pressing on an activation button that removes a dome lock. WO 2013/043938 PCT/US2012/056435 6)~
Patent AU-2018201564-A1 (AU)
Title: Estimation of tissue thickness from rate of change of catheter temperature
Inventor: GOVARI ASSAF
IPC: A61M25/00
Filed: 2018-03-05
Abstract: Apparatus, consisting of a probe having a distal end that is configured to be inserted into contact with 5 tissue. An electrode is attached to the distal end, and there is a temperature sensor incorporated in the distal end and configured to output a temperature signal. A radiofrequency (RF) signal generator is configured to apply a pulse of RF electrical energy via the electrode 10 to the tissue, so as to heat the tissue. The apparatus includes processing circuitry that is configured to compute, based on the temperature signal, a rate of temperature change of the distal end following termination of the pulse, and to estimate a thickness of 15 the tissue in response to the rate of temperature change. 3559485v1 _ _ _ W__ - \ LO D (0WD(OD W OF N -0 0 < Z) 00 W 0c 0- 12 < <Oc w cO U 0 I- C/) 0 CO) -J uWJ 2 z C)D C) uJ 00 08 wI (D ~ 0 D 0 _j C.) 00 01111r LO w 00 ( 0 co 2 <. c U- L~tO (.
Patent AU-2018201813-A1 (AU)
Title: Headgear, interface and an assembly
Inventor: GULLIVER LAURENCE
IPC: A61M16/06
Filed: 2018-03-14
Abstract: - 30 HEADGEAR, INTERFACE AND AN ASSEMBLY This invention relates to a headgear component as a part of a headgear. The component comprising a backstrap, a first ear loop extending from one end of the 5 backstrap, the first ear loop following a path defining a first ear opening, and a second ear loop extending from another end of the backstrap, the second ear loop following a path defining a second ear opening. A first pair of connection zones is on the first ear loop, each connection zone spaced an equal distance from the backstrap and spaced from each other, and a second pair of connection zones on the second ear loop, each 10 connection zone spaced an equal distance apart from the backstrap and spaced from each other. A connection zone of the first pair and a connection zone of the second pair are on a first side of the backstrap, and a connection zone of the first pair and a connection zone of the second pair are on a second (other) side of the backstrap, wherein the headgear component is substantially of a symmetrical shape. Figure to accompany abstract: 2 WO 2013/172719 PCT/NZ2013/000082 8,9,15
Patent AU-2018204568-A1 (AU)
Title: Plant regulatory elements and uses thereof
Inventor: PETERSEN MICHAEL W
IPC: C07H21/04
Filed: 2018-06-22
Abstract: The invention provides recombinant DNA molecules and constructs, as well as their nucleotide sequences, useful for modulating gene expression in plants. The invention also provides transgenic plants, plant cells, plant parts, and seeds comprising a recombinant DNA molecule comprising a DNA molecule operably linked to heterologous transcribable DNA molecule, as are methods of their use.
Patent AU-2018208662-A1 (AU)
Title: Methods and Compositions for Treating Schizophrenia
Inventor: GALLAGHER MICHELA
IPC: A61K31/55
Filed: 2018-07-24
Abstract: The invention relates to methods and compositions for treating schizophrenia or bipolar disorder (in particular, mania) by using a combination of a synaptic vesicle protein 2A (SV2A) inhibitor and an antipsychotic or their pharmaceutically acceptable salts, hydrates, solvates, polymorphs, and prodrugs thereof. The methods and the compositions can be used for treating one or more positive and/or negative symptoms, as well as cognitive impairment, associated with schizophrenia or bipolar disorder (in particular, mania).
Patent AU-2018216302-A1 (AU)
Title: Herbo-mineral formulation for the treatment of cancer and method of preparation thereof
Inventor: SHETTY M VIJAYABHANU
IPC: A61K36/708
Filed: 2018-02-06
Abstract: Herbo-mineral formulation for the treatment of cancer and method of preparation are disclosed herein. The disclosed formulation includes a combination of herb and mineral components that facilitate in controlling abnormal cell proliferation. The formulation can thus be used in treatment of cancer and related mobidities.
Patent AU-2018224411-A1 (AU)
Title: Method for the manufacture of Efavirenz
Inventor: WATTS PAUL
IPC: C07D265/36
Filed: 2018-02-15
Abstract: This invention relates to a method for the manufacture of optically pure (
Patent AU-2018229197-A1 (AU)
Title: Locking fastener with deflectable lock
Inventor: HESS HAROLD
IPC: F16B13/04
Filed: 2018-02-23
Abstract: A locking mechanism for a fastener is provided. The locking mechanism includes a lock nut, a lock member, and a lock washer. The lock nut is releasably coupled to the lock nut for rotation therewith. The lock member includes an annular body having a radially-extending detent member. The lock washer includes an axially-extending wall about a periphery of the lock washer. The axially-extending wall defines an inner cavity for receiving a portion of the annular body of the lock member therein and includes comprising a plurality of radially-extending notches defined therein. The notches are configured to receive the radially-extending detent member.
Patent AU-2018274694-A1 (AU)
Title: Implantable tissue repair devices and methods for manufacturing the same
Inventor: WALKER ROBERT ALAN
IPC: A61F2/30
Filed: 2018-05-22
Abstract: The current invention provides for an implantable tissue repair device comprising: a body comprising a biocompatible hydrogel; and a rigid support at least partly located within the body or device, or connected to the body or device.
Patent AU-2018295693-A1 (AU)
Title: Trolley wire bending tool
Inventor: SEKINE AKIRA
IPC: B60M1/28
Filed: 2018-06-26
Abstract: The objective of the present invention is to improve the workability of a trolley wire bending tool. To this end, the trolley wire bending tool is provided with: a pair of handles 21, 22 which are linked rotatably to one another and into which a rotation operation is input from a rotating end portion thereof; a first contacting portion 30 and a second contacting portion 40 which come into contact from one side of the outer periphery of a trolley wire T; and a third contacting portion 50 which comes into contact from the opposite side of the outer periphery of the trolley wire; wherein the pair of handles are moved by means of a lever construction in such a way that the first contacting portion and the second contacting portion move relatively toward or away from the third contacting portion, the rotating end portions of the pair of handles are positioned toward one end, in the longitudinal direction, of the tool, and the first to third contacting portions are positioned toward the other end, in the longitudinal direction, of the tool.
Patent AU-2018301511-A1 (AU)
Title: Energy monitor
Inventor: CLIFTON ERIC DOUGLAS
IPC: G01R19/25
Filed: 2018-07-13
Abstract: A system for detecting current magnitudes in a circuit breaker panel includes multiple 3-sensor magnometers placed over the main breaker and branch circuits in the circuit breaker enclosure. The sensors communicate with a local processing node, which analyzes the raw data to compensate for external and local interference, and provides an estimated current measurement. The estimated current measurement is then communicated back to a user system which can then use the information to better manage current input and output.
Patent AU-2018301809-A1 (AU)
Title: Method of operating a wastewater treatment system
Inventor: KRASOVIC JULIA LYNNE
IPC: C02F1/461
Filed: 2018-07-12
Abstract: A method for operating a wastewater treatment system is disclosed wherein the wastewater treatment system comprises at least one electrochemical cell comprising dimensionally stable electrodes having the same catalyst composition, the electrodes being immersed in wastewater and being connected to a power supply and wherein the voltage at the power supply is monitored and the polarity of the electrochemical cell(s) is reversed when the recorded voltage increases by a predetermined voltage difference. The wastewater treatment system can comprise at least one electrochemical cell which is kept inactive while the active electrochemical cells are operating. The inactive cell(s) can be activated when all the electrodes of the active cells are consumed as indicated by another increase in voltage at the power supply after the polarity of the active cells has been once reversed.
Patent AU-2018330755-A1 (AU)
Title: Displaying a virtual image of a building information model
Inventor: MITCHELL DAVID JOHN
IPC: G01C15/00
Filed: 2018-09-06
Abstract: A headset for use in displaying a virtual image of a building information model (BIM) in relation to a site coordinate system of a construction site. The headset comprises an article of headwear having one or more position-tracking sensors mounted thereon, augmented reality glasses incorporating at least one display, a display position tracking device for tracking movement of the display relative to at least one of the user's eyes and an electronic control system. The electronic control system is configured to convert a BIM model defined in an extrinsic, real world coordinate system into an intrinsic coordinate system defined by a position tracking system, receive display position data from the display position device and headset tracking data from a headset tracking system and render a virtual image of the BIM relative to the position and orientation of the article of headwear on the construction site and relative position of the display relative to the user's eye and transmit the rendered virtual image to the display which is viewable by the user as a virtual image of the BIM.
Patent AU-2018341335-A1 (AU)
Title: Self-contained ocular surgery instrument
Inventor: WILEY WILLIAM J
IPC: A61F9/007
Filed: 2018-09-25
Abstract: A self-contained ocular surgery instrument, including a power module having a body presenting a mating coupler and including a compressed gas supply; a fluid reservoir; an aspiration pump; an aspirated material reservoir and a control panel. The mating coupler is structured to receive and couple to at least one module that facilitates performance of an eye surgery task. The compressed gas supply is coupled to the aspiration pump and the aspirated material reservoir is in fluid communication with the aspiration pump to receive aspirated material from the mating coupler. The fluid reservoir is in fluid communication with the mating coupler such that fluid is supplied under pressure to the mating coupler and thus to the at least one module that facilitates performance of an eye surgery task. The control panel is in controlling communication with the compressed gas supply, the aspiration pump and the aspirated material reservoir.
Patent AU-2018366384-A1 (AU)
Title: Particulate material production process
Inventor: YU CHENGZHONG (MICHAEL)
IPC: C12N15/88
Filed: 2018-11-14
Abstract: The present invention relates to a process for producing a plurality of hollow inorganic nanoparticles, which process comprises: (a) contacting a first monomer and a second monomer in a solvent to produce a composition comprising the solvent and a plurality of polymer nanoparticles; (b) adding an inorganic compound precursor to the composition comprising the solvent and the plurality of polymer nanoparticles to produce a composition comprising the solvent and a plurality of inorganic compound- coated polymer nanoparticles; (c) adding an additional amount of the first and second monomers to the composition comprising the solvent and the plurality of inorganic compound-coated polymer nanoparticles to produce a composition comprising the solvent and a plurality of composite nanoparticles; and (d) heating the plurality of composite nanoparticles to produce the plurality of hollow inorganic nanoparticles, wherein in step (a) the first monomer and the second monomer are contacted in the solvent at a temperature of at least 30°C. The present invention also relates to plurality of hollow inorganic nanoparticles and uses thereof.
Patent AU-2018420716-A1 (AU)
Title: Controllable pressure injection apparatus based on hydraulic accumulator and method therefor
Inventor: LIU SONGYONG
IPC: E21C37/08
Filed: 2018-09-21
Abstract: Provided are a controllable pressure jetting apparatus based on a hydraulic energy accumulator and a jetting method. The jetting apparatus comprises a pressure storage system, a pressure holding system, a sealing system and an injection system. The pressure storage system comprises a front half (4-2) of a pressure cylinder, an annular piston (5) and a middle connection body (7). The pressure holding system comprises an energy accumulator (2), a rear half (4-1) of a pressure cylinder, and a rear end cover (1). The sealing system comprises a hydraulic propulsion cylinder (8), a propulsion piston (9), a front end cover (10), a sealing tube (12), a thickened end part (14) and an expanding rubber tube (13). The jetting system comprises a hydraulic valve body (6) and a jetting gun tube (11). The jetting apparatus can quickly apply pressure to the bottom of a drilling hole in a hydraulic manner, so that rock is broken under tension, thereby improving the excavating efficiency of hard rock.
Patent WO-2019136516-A1 (WO)
Inventor: HALASZ MARIA
IPC: A61P9/10
Filed: 2019-01-09
Abstract: La présente invention concerne des procédés et des réactifs pour le traitement ou la prévention d'une myocardite et/ou d'une cardiomyopathie. Par exemple, le procédé et les réactifs de l'invention peuvent être utiles pour le traitement ou la prévention de l'hypertrophie cardiaque et/ou pour la prévention de la fibrose cardiaque et/ou pour l'amélioration de la fonction cardiaque chez un sujet souffrant d'une cardiomyopathie. En particulier, la présente invention concerne l'utilisation d'un anticorps isolé ou recombinant ou d'un fragment de liaison à l'antigène correspondant, qui se lie au domaine N-terminal de la protéine midkine (MK) et qui inhibe ou réduit la fonction de MK dans le traitement ou la prévention d'une myocardite et/ou d'une cardiomyopathie.
Patent WO-2020000025-A1 (WO)
Title: Ensemble de verrouillage à mode de confidentialité amélioré
Inventor: CONSTANTINOU JOHN
IPC: E05B13/00
Filed: 2019-06-20
Abstract: L'invention concerne un dispositif de mode de confidentialité (40) dans un ensemble de verrouillage (1) comprenant : un élément d'actionneur (41) pour une entrée manuelle d'une force d'actionnement par un utilisateur pour activer un mode de confidentialité de l'ensemble de verrouillage (1), l'élément d'actionneur (41) étant configuré pour se déplacer d'une position de départ à une position activée ; et un mécanisme de transfert de force (44) permettant de transférer la force d'actionnement de l'élément d'actionneur (41) à un élément de tourniquet (42) du dispositif de mode de confidentialité (40) pour déplacer l'élément de tourniquet (42) pour la mise en prise et le verrouillage d'une poignée de porte externe de l'ensemble de verrouillage (1) contre la rotation dans le mode de confidentialité ; le mécanisme de transfert de force (44) étant configuré pour augmenter la force transférée à l'élément de tourniquet (42) progressivement lorsque l'élément d'actionneur (41) se déplace de la position de départ à la position activée. L'invention concerne également un ensemble de verrouillage (1) comprenant le dispositif de mode de confidentialité (40).
Patent WO-2020061626-A1 (WO)
Inventor: IRWIN LEE
IPC: B65D19/38
Filed: 2019-09-25
Abstract: Provided is a pallet transit frame (10) comprising four operatively downward extending legs (12) each defining a foot (14) configured to engage a corner of a lower pallet (8) and/or a ground surface, as well as first and second cross beams (16 and 18) supported by said legs (12.) Each beam (16 and 18) defines a shoulder (20) at both ends thereof configured to engage corners of an upper pallet (6), wherein the pallet transit frame (10) is able to straddle the lower pallet (8) and support the upper pallet (6) on the shoulders (20) and/or cross beams (16 and 18) during transport.
Patent WO-2020077411-A1 (WO)
Inventor: LISOWSKI LESZEK
IPC: C40B40/02
Filed: 2019-10-17
Abstract: La présente invention concerne de manière générale des molécules d'acide nucléique et des procédés d'identification de vecteurs AAV ayant des propriétés souhaitables, notamment des molécules d'acide nucléique et des procédés utiles pour identifier de nouveaux gènes cap pour la vectorisation, la production de vecteurs AAV et de bibliothèques d'AAV.