baber/WOPTO huggingface dataset:
Patent ES-2248915-T3 (ES)
Title: Preparados de aerosol acuosos que contienen macromoleculas biologicamente activas y procedimiento para producir aerosoles correspondientes.
Inventor: LAMCHE HERBERT
IPC: A61K9/12
Filed: 1998-07-31
Granted: 2006-03-16
Abstract: Nebulizador exento de gas propulsor que contiene un preparado de aerosol en forma de una solución con agua o una mezcla de agua y etanol como disolvente, que contiene una sustancia activa en una concentración entre 25 y 100 mg/ml, elegido del grupo de oligonucleótidos antisentido orexinas eritropoyetina factor de necrosis de tumores-alfa factor de necrosis de tumores-beta GM-CSF ("factor estimulador de colonias de granulocitos y macrófagos" de "granulocyte- macrophage colony stimulating factor") anexinas calcitonina leptinas hormonas paratiroideas fragmentos de hormonas paratiroideas interleuquinas tales como p.ej. interleuquina 2, interleuquina 10 e interleuquina 12 insulina superóxido dismutasa un interferón ICAM ("molécula de adhesión intercelular", de "intercellular adhesion molecule") soluble somatostatina somatotropina tPA ("activador de plasminógeno de tipo tisular", de "tissue plasminogen activator") TNK-tPA antígenos asociados a tumores (en forma de péptido, proteína o ADN) antagonistas del péptido bradiquinina urodilatina GHRH ("hormona liberadora de la hormona del crecimiento", de "growth hormone releasing hormone") CRF ("factor de liberación de corticotropina", de "corticotropin releasing factor") EMAP II heparina receptores de interleuquinas solubles, tales como el receptor de sIL-1 vacunas, tales como la vacuna de hepatitis o la vacuna de sarampión polinucleótidos antisentido factores de transcripción, en donde el nebulizador exento de gas propulsor es adecuado para medir en una cámara de medición una cantidad terapéuticamente eficaz de una dosificación individual del preparado de aerosol y de atomizar bajo alta presión, entre 100 y 500 bares, a través de por lo menos una boquilla con un diámetro hidráulico de 1 a 12 micrómetros para formar gotitas inhalables con un tamaño medio de partículas menor que 10 micrómetros.
Patent ES-2172203-T3 (ES)
Title: Accionador con un elemento flexible, y estribo de freno que comprende dicho accionador.
Inventor: RINSMA ANDRIES CHRISTIAN
IPC: F16D65/18
Filed: 1998-09-30
Granted: 2002-09-16
Abstract: Accionador (7), que comprende un alojamiento (4), un motor (8), un elemento accionador (25) y un mecanismo de tornillo (10) que proporciona un movimiento lineal del elemento accionador (25, 35) con respecto al alojamiento (4) en respuesta a un movimiento rotatorio del motor (8); dicho mecanismo de tornillo (10) incluye un tornillo (24) y un émbolo (22) uno de los cuáles se sostiene rotativamente con respecto al alojamiento (4), caracterizado por el hecho de que el mecanismo de tornillo (10) y el elemento accionador (25, 35) se engranan a través de un relleno de presión elástico (36) que incluye dos barras de entramado generalmente paralelas (41); dichas barras de entramado (41) están conectadas respectivamente a lo largo de su circunferencia (42) e incluyen un espacio interno cerrado que se llena con un fluido (43).
Patent ES-2252858-T3 (ES)
Inventor: TREMOULET OLIVIER L JR
IPC: F16J15/16
Filed: 1998-09-17
Granted: 2006-05-16
Abstract: A coupling for a high pressure fluid pump assembly is shown and described. The plunger has a rounded convex engagement surface. A second engagement portion of the extension rod has a substantially flat second engagement surface engaging the first engagement surface of the plunger. The interface between the first and second engagement surfaces aligns motion of the plunger along the first axis with motion of the extension rod along the second axis, reducing their tendency to bend and to move laterally relative to their respective longitudinal axis.
Patent ES-2247727-T3 (ES)
Inventor: TANG XIAOZHONG
IPC: A61Q15/00
Filed: 1998-10-26
Granted: 2006-03-01
Abstract: The present invention comprises stabilizing aqueous solutions of aluminum zirconium based salts with a water soluble amino acid, especially glycine, wherein the Zr:glycine weight ratios used to form solutions of the active itself or used to form cosmetic compositions made according to this invention are in the range from 1:1.2 to 1:5, particularly 1:2 to 1:4, and more particularly in the range of 1:2 to 1:3 on a weight:weight basis. By reducing the polymerization of small zirconium species with an elevated amount of amino acid(s), the efficacy of the antiperspirant salts is maintained.
Patent ES-2317680-T3 (ES)
Inventor: KONTERMANN ROLAND DR
IPC: C12N5/10
Filed: 1999-04-08
Granted: 2009-04-16
Abstract: Single-chain molecule (I) that binds multiple antigens comprises two variable domains of heavy immunoglobulin chains (VH), having specificities A and B and two variable domains of light chains (VL), also with specificities A and B. The domains are provided as two VH-VL constructs which are attached via a peptide (P). Any VH and VL may be replaced by their functional fragments. Independent claims are also included for the following: (1) nucleic acid (II) encoding (I); (2) vectors containing (II); (3) cells containing (II) or the vectors; (4) recombinant production of (I) by culturing these cells; (5) pharmaceutical composition containing (I), (II), the vectors or cells; and (6) diagnostic composition containing (I). ACTIVITY : Anticancer; antiviral; antibacterial; antimalarial; antiinflammatory. MECHANISM OF ACTION : Specific binding interaction.
Patent ES-2202951-T3 (ES)
Title: Dispositivo de estampado.
Inventor: SPATAFORA MARIO
IPC: B21D31/00
Filed: 1999-04-06
Granted: 2004-04-01
Abstract: UNIDAD DE ESTAMPACION EN RELIEVE (1) CON UNA ESTRUCTURA (8) QUE SOSTIENE UN PAR DE RODILLOS DE ESTAMPACION (3,4) POR MEDIO DE DOS SOPORTES (13,16), EL PRIMERO DE LOS CUALES (13) FORMA PARTE INTEGRANTE DE LA ESTRUCTURA (8) Y ESTANDO UNIDO EL SEGUNDO (16) A LA ESTRUCTURA (8) POR MEDIO DE UNA CONEXION ESFERICA (24) Y SIENDO EMPUJADO HACIA EL OTRO SOPORTE (13) POR LA FUERZA QUE GENERAN UN PAR DE ELECTROIMANES (30).
Patent ES-2262268-T3 (ES)
Inventor: KAPLAN ANDREAS DR RER NAT
IPC: C07C231/22
Filed: 1999-05-20
Granted: 2006-11-16
Abstract: Preparation of  beta -hydroxyalkylamide from the corresponding alkyl ester and  beta -amino alcohol in the absence of solvent but in the presence of a basic catalyst involves (i) using a ratio of ester equivalents:amine equivalents of 1:1.001-8, (ii) decomposing the basic catalyst after the aminolysis and (iii) separating off any unreacted amino alcohol. Preparation of  beta -hydroxyalkylamides of formula (I) comprises reacting the corresponding alkyl ester and  beta -amino alcohol in the absence of solvent but in the presence of a basic catalyst and removing the alcohol produced. The ratio of ester equivalemts:amine equivalents is 1:1.001-8. The basic catalyst is decomposed after the aminolysis and unreacted amino alcohol is separated off. (HO-C(H)(R1)-CH2-N(R2)-C(=O)-)n-A-(-C(=O)-N(R2)-CH2-C(H)(R1)-OH)n' (I) A = a bond or a polyvalent organic group selected from (optionally unsaturated) 1-60 alkyl, cycloalkyl, aryl, carboxyalkenyl, alkoxycarbonylalkenyl or trialkylenamino, or, when n' = 0, H or a monovalent group; R1 = H or 1-5C alkyl; R2 = H, 1-5C alkyl or HO-C(H)(R1)-CH2-; n = 1-10; and n' = 0-2.
Patent ES-2234199-T3 (ES)
Inventor: MEINL JURGEN
IPC: G02B6/255
Filed: 1999-11-09
Granted: 2005-06-16
Abstract: The method involves making a bundle (1) from individual fibres that are pressed together at one end in a metal sleeve (3) applying temperature and pressure. Ends of fibres are automatically pulled into a single metal sleeve to form a round, tightly packed bundle, which is fixed axially and radially by a clamp near the metal sleeve. The end is heated (6) to deformation temperature and compressed to form a hexagonal package before cooling. Independent claims are also included for an arrangement for manufacturing optical fibre bundles and for an optical fibre bundle
Patent ES-2285823-T3 (ES)
Title: Envoltura de materia elastica rigida para alojar aparatos electricos.
Inventor: DUMON DIPUIS MICHEL
IPC: H02B1/30
Filed: 1999-07-27
Granted: 2007-11-16
Abstract: Se presenta una funda de plástico rígido para accesorios eléctricos. La funda comprende un panel trasero vertical 811) y paneles verticales y laterales moldeados. Unas pestañas rígidas de fijación (50) con unas orejetas (54) se alojan en unas cavidades (56) de los paneles verticales. Las pestañas de fijación se fijan al panel trasero mediante tornillos (63).
Patent ES-2209391-T3 (ES)
Title: Anticuerpo monoclonal que reconoce el oligosacarido acido sialico n-glicolilado-galactosa-glucosa en los tumores malignos y su composicion.
Inventor: CARR PEREZ ADRIANA
IPC: C12P21/08
Filed: 1999-02-05
Granted: 2004-06-16
Abstract: La presente invención se refiere a la rama de la inmunología y de la medicina humana, en particular a la generación y selección de un anticuerpo monoclonal que recopnoce el oligosacarido ácido sialico N - glicolilo - galactosa - glucosa (N - GcNeu - Gal - Glu) present en tumores malignos. Uno de los objetos de esta invención es obtener un anticuerpo monoclonal de tipo igG1 que tiene la característica de reconocer con una gran especificidad la secuencia de oligosacárido ácido sialico N - glicolilo - galactosa - glucosa presente en tejidos de mamarios maligno así como en melanomas y tumores del hígado, el estómago, el colón, el recto y el riñón. También tiene la capacidad de provocar la histolisis directa en células tumorales que llevan dichas secuencias de oligosacárido y como consecuencia, puede utilizarse para el diagnóstico y el tratamiento de ciertas enfermedades neoplásicas. Otro objeto de la presente invención es conseguir el hibridoma que produce dicho monoclonal, así como la composición farmacéutica que lo contiene, para el tratamiento de enfermedades neoplásicas.
Patent ES-2229701-T3 (ES)
Inventor: JARROUSSE FRANCOISE
IPC: A61Q7/00
Filed: 1999-05-11
Granted: 2005-04-16
Abstract: A method for inducing and/or stimulating the growth of hair and/or slowing down hair loss comprising administering an effective amount of at least one metalloprotease inhibitor or any functional biological equivalent thereof and an acceptable carrier therefor.
Patent ES-2207205-T3 (ES)
Inventor: PARETI VITTORIO
IPC: B24D5/12
Filed: 1999-05-20
Granted: 2004-05-16
Abstract: The invention is in the field of cutting disks employed in the construction industry for cutting concrete and construction materials in general and in industrial applications for cutting wood, glass and metals. More specifically the invention relates to a sheet (1) able to be attached to the cutting disk. The sheet comprises one or more layers (3) of synthetic fabric such as carbon fibre, glass fibre, or combinations of carbon fibre with glass fibre. The sheet comprises a layer of adhesive (4) able to adhere to the surface of the cutting disk.
Patent ES-2220069-T3 (ES)
Title: Composicion que tiene baja resistividad termica y procedimiento para cubrir cables de transporte de energia electrica.
Inventor: CASLINI DANILO
IPC: C04B28/02
Filed: 1999-05-26
Granted: 2004-12-01
Abstract: Procedimiento de colocación de cables dispuestos en una zanja, que comprende las etapas de: -extraer la tierra original de tal manera que se prepare dicha zanja; -disponer una primera capa de una primera composición en dicha zanja; -disponer los cables encima de dicha primera capa; -disponer una segunda capa de dicha primera composición encima de dichos cables; -disponer una tercera capa encima de dicha segunda capa formada por una segunda composición de tal manera que se rellene dicha zanja; caracterizado porque dicha primera composición comprende: 60-90% en peso de arena triturada; 4-15% en peso de cieno; 2-12% en peso de cemento; 4-15% en peso de agua.
Patent ES-2291039-T3 (ES)
Inventor: GAJEWCZYK DIANE M
IPC: A61K39/00
Filed: 1999-09-03
Granted: 2008-02-16
Abstract: Vectors for DNA immunization against cervical cancer comprise a nucleic acid molecule encoding at least one none-toxic T-cell epitope of the E6 and/or E7 antigens of a strain of human papilloma virus (HPV) associated with cervical cancer, such as HPV-16, and a promoter operatively coupled to the nucleic acid molecule for expression of the nucleic acid molecule in a host to which the vector is administered.
Patent ES-2318906-T3 (ES)
Inventor: FISCHER M PETER
IPC: C07K14/435
Filed: 1999-11-11
Granted: 2009-05-01
Abstract: The invention relates to modified and truncated forms of the membrane transport vector penetratin. Such truncated forms include 7-mer peptides that may in themselves include further variation.
Patent ES-2191483-T3 (ES)
Title: Caperuza para el cierre de botellas de vino.
Inventor: LIGERAS ACHILLES P
IPC: B65D41/08
Filed: 1999-11-12
Granted: 2003-09-01
Abstract: Dispositivo para la extracción y substitución de un tapón de corcho a utilizar con la botella de vino (14), que tiene el tapón de corcho (40) que define una superficie superior y un cuello de botella (12), estando destinada la botella (14) a contener vino, y en el que unos hilos de rosca salientes (24¿) se prolongan hacia afuera con respecto a dicho cuello (12), proporcionando dichos hilos de rosca (24¿) una primera dirección que posibilita el desmontaje de dicho tapón de corcho (40) con respecto a la botella de vino (14) y una segunda dirección para substituir dicho tapón de corcho (40) después de la utilización del vino, comprendiendo: (a) una caperuza (26) que tiene una parte superior (28) con un borde y un faldón (32) y que define una abertura inferior (30) y filetes de rosca (54) dirigidos hacia adentro que sobresalen del interior de dicho faldón (32); (b) dicha parte superior define el rebaje central (34) tiene paredes rebajadas; (c) dicho rebaje central (34) tiene una pared inferioro de fondo con una abertura en la misma; y (d) un tornillo (42) que se prolonga a través de dicha abertura de la pared de fondo hacia adentro del tapón de corcho (40), poseyendo dicho tornillo (42) hilos de rosca para conseguir una dirección de atornillado, caracterizado porque: el rebaje (34) está dotado de prolongaciones del rebaje (38) que se extienden radialmente, dirigidas hacia afuera y alineadas desde dicho rebaje central (34) al borde superior, siendo el tornillo (42) un tornillo de cabeza hemisférica y siendo la dirección de atornillado opuesta a dicha primera dirección para posibilitar la retirada de dicho tornillo (42) con respecto al tapón de corcho (40).
Patent ES-2351625-T3 (ES)
Inventor: DE VOLDER LAURENT
IPC: B41C1/05
Filed: 1999-10-26
Granted: 2011-02-08
Abstract: Process for engraving an image in a support, wherein said image is provided for pad printing, wherein the latter forms an intermediate support which is first charged with ink, after which the ink is scrapped off, wherein a flexible pad means takes over the remaining ink which is originating from the engraved support, whereby a transposed image is formed, after which said transposed image is deposited on a surface to be printed of an object to be decorated by means of the pad means which is charged with ink, remarkable in that the engraving of said image (11, 12) is effected in that a high energy beam (9) is directed on said support (10) according to a selected image pattern (11, 12) and under parametric working conditions which are set.
Patent PL-1460357-T3 (PL)
Title: Wire-and-tube condenser for refrigeration appliances
Inventor: GIRO MARINO
IPC: F28F1/12
Filed: 2004-03-01
Abstract: Wire-and-tube condenser, which is exposed to vibrations coming from the compressor, comprises a tubular coil (10) defining a plurality of rectilinear tubular sections (12) that extend parallel to each other, are fluidly joined to each other by curved portions (14) and are connected to each other by means of a plurality of rigid metal wires (16), which are welded in an orthogonal direction to both sides of said rectilinear tubular sections. <??>At least a portion of the tube coil (10) is provided with a further curved section (24), which is inserted, and held securely in place by press-fitting, between the wires (16) welded to the rectilinear tubular sections (12). <IMAGE>
Patent PL-1464650-T3 (PL)
Title: Novel estrogenic compounds, obtainable by heat treatment of conjugated estrogens in high humidity
Inventor: HILL EDWARD N
IPC: C07J31/00
Filed: 2004-04-02
Abstract: The present invention relates to novel estrogenic compounds. The present invention also relates to methods of treating estrogen deprivation in a subject comprising administering novel estrogenic compounds. Additionally, the present invention relates to methods of synthesizing novel estrogenic compounds.
Patent PL-1504998-T3 (PL)
Title: Labeling machine
Inventor: SCHINELLI NICOLA
IPC: B65C9/04
Filed: 2004-07-28
Abstract: A labeling machine (1), comprising a rotating carousel (6) that supports a plurality of pans (8a), each of which is designed to receive and support a bottle (8c) when the bottle is in a specific position, the pans being provided with elements adapted to turn them while they travel along a portion that is comprised between a rotation start position (15) and a rotation end position (17), the rotation start position being arranged upstream, in the direction of rotation of the carousel, with respect to a position in which each pan (8a) receives and supports a bottle (8c). <IMAGE>
Patent PL-1494060-T3 (PL)
Title: Apparatus for searching and detecting flaws in parts by endoscopy
Inventor: BONNINGUE ISABELLE
IPC: G02B23/26
Filed: 2004-06-29
Abstract: The device has an endoscope (22), for lighting and observation in visible light, with conduits to supply and pulverize products for inspection in a stick (16) passing via an orifice (14) of a wall (10) to examine a piece (12). Another endoscope independent of the former endoscope and the stick is provided for lighting and observation of a portion of the piece processed by the products for inspection in ultraviolet light.
Patent PL-1636391-T3 (PL)
Title: Support for structural components
Inventor: SCHEIBEL THORSTEN
IPC: C21D9/00
Filed: 2004-06-14
Abstract: A support for structural components that are subjected to a thermal treatment process. The support includes a frame having limbs and extending therefrom a grid of intersecting strands. In order to prevent the support from warping even when subjected to strong thermal loads or variations in temperature, the frame is produced from a temperature-resistant material and the strands are produced from carbon fibers or ceramic fibers that form the grid, extending from the limbs of the frame.
Patent PL-1678024-T3 (PL)
Title: Device for locking mobile point elements, especially point closing elements
Inventor: KLEIN HERBERT
IPC: B61L5/10
Filed: 2004-10-15
Abstract: The invention relates to a device for locking end positions of mobile point elements, especially a point closing element, said device comprising at least two parts that can be moved in relation to each other, are guided inside each other, and can be displaced into a non-positively or positively coupled position, in at least one direction of displacement. According to the invention, said mobile parts are formed by an inner tube (14) and an outer tube (13) surrounding the inner tube (14), said tubes encompassing a fixed rod (5).
Patent PL-1673275-T3 (PL)
Title: Process, device and computer program for simulation of a locking wedge
Inventor: TASSAKOS CHARALAMBOS
IPC: B62D65/06
Filed: 2004-08-07
Abstract: The invention relates to a method and a device (1) for adjusting the gap dimensions and/or an offset between a movable hood (2) of a motor vehicle and the remaining body (3) of said motor vehicle. The hood (2) is first fitted and retained in a roughly adjusted assembly position so as to be as flush as possible with the body (3), whereupon the hood (2) is finely adjusted such that predefined values are matched as closely as possible for the gap dimensions and/or the offset. In order to be able to adjust the gap dimensions and/or the offset as simply, quickly and flexibly as possible in a contactless manner, actual values (21 ist) for the gap dimensions and/or the offset between the hood (2) and the remaining body (3) are optically detected for the fine adjustment. Triggering signals (24) for at least one actuating member (12) are determined in accordance with the detected actual values (21 ist) and predefined set point values (21-soll) for the gap dimensions and/or the offset.
Patent PL-1685285-T3 (PL)
Title: Fabric hose and blocking thread for use in a fabric hose
Inventor: PIWONSKI TIMO
IPC: D03D3/02
Filed: 2004-10-07
Abstract: The invention relates to a double-layer woven fabric hose (10) that can be radially shrunk, comprising an upper and a lower fabric layer (8; 9). Said fabric layers (8; 9) are interconnected at their edges by binding warp threads (5). The hose also comprises weft threads (1; 2) consisting of a material with excellent shrinking qualities and warp threads (11; 12) consisting of a material with poor shrinking qualities. The binding warp threads (5) are configured as blocking threads with an alternating thick and thin structure.
Patent PL-1649478-T3 (PL)
Title: Rotary engagement lock mechanism for automatic safety cutout
Inventor: ANTICO CHRISTOPHE
IPC: H01H71/52
Filed: 2004-07-20
Abstract: The mechanism has a spring mechanism (38) and a lever (8) with a stop surface. The surface and a coupling surface (22) define housing with walls forming a stop when a coupling lever (18) is in stable position. A coupling end of a hand-lever (3) is forced against the stop. The surface (22) is conformed such that at all points of the surface, a normal to the surface is oriented along a direction meeting a rotating axis of the lever (18).
Patent PL-1682232-T3 (PL)
Title: Device for preventing and extinguishing fires
Inventor: WAGNER ERNST WERNER
IPC: A62C99/00
Filed: 2004-11-09
Abstract: A device for the prevention and extinguishing of fires is specified having the objective of providing an inert gas fire extinguishing system which is configured in accordance with the invention such that no breaches to ceilings or walls need be made when mounting the supply line system ( 4 ) during installation of the fire extinguishing system in a target area ( 1 ), and also having the further objective of dispensing with separate storage areas for the pressurized oxygen-displacing gas ( 3 ) used as extinguishing agent, wherein a buffer reservoir ( 2 ), the supply line system ( 4 ) and extinguishing nozzles ( 5 ) are arranged as a compact modular unit right within target area ( 1 ) itself.
Patent PL-1740465-T3 (PL)
Title: Guiding, distributing and filling device, and method for use thereof
Inventor: DE GREEF JACOB HENDRIK
IPC: B65B25/04
Filed: 2005-04-28
Abstract: The present invention relates to a method for uniformly filling a relatively large container (5) with relatively delicate products, wherein the products are supplied at a first level using a feed conveyor (17), and these products are transferred by means of a guiding device which guides the products in restrained manner from the first level to a second level, wherein at the second level the products are released into a distributing device (3) for distribution in the container. The invention further relates to a guiding device (2) for guiding products from a feed conveyor, comprising: —at least one transfer member (11) comprising means for receiving the products at a speed which can be adjusted to the speed of the feed conveyor, —a guide member (12) which is arranged substantially along a part of the outside of the transfer member for guiding the products in the transfer member.
Patent PL-1861352-T3 (PL)
Title: Method for producing optically active 3-phenylpropionic acid derivatives and follow-on products of the latter
Inventor: HETTCHE FRANK
IPC: C07C51/41
Filed: 2006-03-16
Abstract: The present invention relates to a method for preparing optically active 3-phenylpropionic acid derivatives, to optically active 1-chloro-3-phenylpropane derivatives obtainable therefrom and to optically active intermediates obtained thereby.