Patent GB-655875-A (GB)
Title: Improvements in or relating to pesticidal compositions
IPC: C07F9/10
Filed: 1947-11-20
Abstract: Organic phosphates having the general formula <FORM:0655875/IV (b)/1> wherein R1 and R2 are alkyl, aralkyl or aryl groups; Z is sulphur or oxygen; Y is NH, N-alkyl, sulphur or oxygen; and X is hydrogen, halogen, alkyl, aryl, alkyloxy, aryloxy, nitro, amino, alkylamino, dialkyl amino, acyl, carboalkyloxy or carboaryloxy; are prepared by reacting an organic chlorophosphate with an alkali-forming metal nitrophenate in the presence of a solvent for the latter, as described in Specification 644,616. Typical phosphates are dimethyl-, ethyl butyl-, didecyl-, and diphenyl-4-nitrophenyl phosphates; di-ethyl-, di-(2-ethyl hexyl)-, ethyl decyl-, di-octadecyl-2-nitrophenyl phosphates; di-(2-ethyl hexyl)-4-bromo - 2 - nitrophenyl phosphate; diethyl - 4 - methyl - 2 - nitrophenyl phosphate; di-ethyl-, di-isopropyl-, dibutyl-, diamyl, di-(2-ethyl hexyl)-, dioctyl-, didecyl-, didodecyl-, dioctadecyl-, di-benzyl-, diphenyl-, N,N-bis-(ethylamido) - 4 - nitrophenyl thiophosphates; O,S - diethyl - 4 - nitrophenyl thiophosphate; diethyl-, diamyl-, di-(2-ethyl hexyl)-2,3-dinitrophenyl thiophosphates; dibutyl-, diphenyl-, dibenzyl-, 2,4-dinitrophenyl thiophosphates; di-isopropyl-, diphenyl-, dibenzyl-, 2,6-dinitrophenyl thiophosphates; diethyl 4 - chloro - 2 - nitrophenyl thiophosphate; ethyl butyl 4-methoxy - 2 - nitrophenyl phosphate; dibenzyl - 2 - methyl - 4 - nitrophenyl thiophosphate; di - (2-ethyl hexyl) - 4 - bromo - 2 - nitrophenyl phosphate; and dibutyl 4-ethoxy-2-nitrophenyl thiophosphate.ALSO:<FORM:0655875/VI/1> A pesticidal composition comprises a mixture of one or more organic phosphates and a carrier therefore, said organic phosphate having the general formula: where R1 and R2 are alkyl, aralkyl or aryl; Z is sulphur or oxygen; Y is NH, N-alkyl, S or O; X is hydrogen, halogen, alkyl, aryl, alkyloxy, aryloxy, nitro, amino, alkylamino, dialkylamino, acyl, carboalkoxy or carboaryloxy; said carrier comprising at least 50 per cent by weight of the composition and being such that if the composition is admixed with or contains water the resulting pH is not greater than 8.5.  The carrier may be liquid, solid or gaseous.  The liquid may be a solvent for the organic phosphate, a non-solvent, a mixture of solvent and non-solvent, the non-solvent having the further addition of an emulsifying agent such as sodium lauryl sulphate.  Specified solvents are ketones, e.g. acetone, cyclohexanone, isophorone and methyl ethyl ketone; monohydric aliphatic alcohols; esters thereof, e.g. acetates, phthalates, abietates, fumarates and maleates; ether alcohols, e.g. polyethylene glycols above the trimer; ketone alcohols such as diacetone alcohol; animal and vegetable oils; polymethylated naphthalenes; aromatic hydrocarbons, e.g. benzene, toluene, xylene. The non-solvent carrier may be water, petroleum ether, kerosene, spray oils, or mixtures of such petroleum hydrocarbons. Gaseous carriers may be air, nitrogen, carbondioxide, methyl chloride and difluo-dichloromethane.  Solid carriers may be clays, talcs, diatomaceous earths, Fuller's earths, pyrophyllites, cellulosic sheets and sawdust.  Typical organic phosphates are dimethyl-, ethyl butyl-, didecyl- and diphenyl 4-nitrophenyl phosphates; di-ethyl-, di-(2 ethyl hexyl)-, ethyl decyl-, di-octadecyl- 2 nitrophenyl phosphates; di (2-ethyl hexyl) 4-bromo-2 nitrophenyl phosphate; diethyl 4-methyl-2-nitrophenyl phosphate; di-ethyl-, di-isopropyl-, dibutyl-, diamyl-, di (2 ethyl hexyl)-, dioctyl-, didecyl-, didodecyl-, dioctadecyl; di-benzyl-, diphenyl-, N,N-bis-(ethylamido)-4-nitrophenyl thiophosphates; O,S-diethyl 4-nitrophenyl thiophosphate; diethyl-, diamyl-, di (2 ethyl hexyl) 2, 3-dinitrophenyl thiophosphates; dibutyl-, diphenyl-, dibenzyl-2,4-dinitrophenyl thiophosphates; diisopropyl-, diphenyl-, dibenzyl-2,6-dinitrophenyl thiophosphates; di ethyl 4-chloro-2-nitrophenyl thiophosphate; ethyl butyl 4-methoxy-2-nitrophenyl phosphate; dibenzyl 2-methyl 4-nitrophenyl thiophosphate; di (2-ethyl hexyl) 4-bromo-2 nitrophenyl phosphate; dibutyl 4-ethoxy-2-nitrophenyl thiophosphate.  The phosphates may be used in combination with nicotine, rotenone, pyrethrum, benzene hexachloride, D.D.T., dodecyl thiocyanate and phenothiazine; with fungicides such as sulphur, copper compounds and mercury salts; and with fertilizers.  Examples of suitable compositions are given.  The organic phosphate may be prepared according to Specification 644,616, [Group IV(b)].  The Specification as open to inspection under Sect. 91 comprises also the addition of lead arsenate or calcium arsenate to the composition of the invention.  This subject-matter does not appear in the Specification as accepted.