baber/WOPTO huggingface dataset:
Patent IL-113280-A0 (IL)
Title: Method of treating auto-immune diseases using type one interferons
IPC: C12N15/09
Filed: 1995-04-06
Abstract: The present invention provides a method of treating auto-immune diseases in an animal comprising the step of orally administering a type one interferon to said animal. Also provided is a method of reducing inflammation associated with an auto-immune disease in an animal comprising the step of orally administering a type one interferon to said animal.
Patent IL-113747-A0 (IL)
Title: Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives polymorphs and pseudomorphs thereof
IPC: A61P37/08
Filed: 1995-05-16
Abstract: The present invention is related to novel processes for preparing anhydrous and hydrated forms of piperidine derivatives, polymorphs and pseudomorphs thereof of the formulas   
which are useful as antihistamines, antiallergic agents and bronchodilators.
Patent IL-115092-A0 (IL)
Title: Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
IPC: A61K31/445
Filed: 1995-08-28
Abstract: The present invention provides a novel process for preparing novel compounds of formula I <CHEM>  wherein R<1> and R<2> each are independently C1-C4 alkyl, or combine to form piperidinyl, pyrrolidinyl, methylpyrrolidinyl, dimethylpyrrolidinyl, morpholino, dimethylamino, diethylamino, or 1-hexamethyleneimino; and     n is 2 or 3;  or a pharmaceutically acceptable salt thereof, comprising     a) reacting a haloalkyl amine of formula III <CHEM>  wherein     X is a halogen; and R<1>, R<2>, and n are as defined above, with a compound of formula IV   <CHEM> wherein R is C1-C6 alkyl, in the presence of an alkyl acetate solvent and a base; b) extracting the reaction product of step a) with an aqueous acid; and c) cleaving the ester of the reaction product from step b) to form an acid.   The present invention further provides a novel process for preparing compounds of formula V <CHEM>  wherein R<1> and R<2> each are independently C1-C4 alkyl, or combine to form piperidinyl, pyrrolidino, methylpyrrolidino, dimethylpyrrolidinyl, morpholino, dimethylamino, diethylamino, or 1-hexamethyleneimino;     R<3> and R<4> each are H or a hydroxy protecting group; and     n is 2 or 3;  or a pharmaceutically acceptable salt thereof, comprising     a) reacting a haloalkyl amine of formula III <CHEM>  wherein     X is a halogen; and R<1>, R<2>, and n are as defined above, with a compound of formula IV   <CHEM> wherein R is C1-C6 alkyl, in the presence of an alkyl acetate solvent and a base; b) extracting the reaction product from step a) with an aqueous acid;   c) cleaving the ester of the reaction product from step b) to form an acid; d) reacting the extracted product from step c) with a compound of formula V <CHEM> wherein R<3> and R<4> are as defined above, or a pharmaceutically acceptable salt thereof; e) optionally removing the R<3> and R<4> hydroxy protecting groups of the reaction product form step d); and f) optionally forming a salt of the reaction product from either steps d) or step e).
Patent IL-123506-A0 (IL)
Title: Compounds and methods for immunotherapy and diagnosis of tuberculosis
IPC: A61K31/711
Filed: 1996-08-30
Abstract: Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M tuberculosis infection, or may be used for the diagnosis of tuberculosis.
Patent IL-127203-A0 (IL)
Title: Calcium nitrate based fertilizer
IPC: C05C5/04
Filed: 1997-05-14
Abstract: Homogeneous calcium nitrate based fertilizers containing sulphur, and method for their preparations. Solid gypsum and/or a slow reacting sulphate mineral is mixed with melted calcium nitrate fertilizer at a temperature of 90-110° C. and kept at this temperature for 3-15 minutes and subsequently particulated at a temperature of 80-110° C. The particulation by prilling is preformed at 95-110 ° C. and the particulation by granulation is performed at 90-110° C. The fertilizer is a homogeneous composition of a calcium nitrate fertilizer and gypsum and/or a slow reacting sulphate mineral comprising 0.1-5.0 weight % SO4-S, 14-19 weight % water soluble calcium and 16-21 weight % total calcium, and 0-3.0 weight % water soluble magnesium. The fertilizer may contain microamounts of Se and/or Co. and/or micronutrients like Mn, Cu, B and Zn.
Patent IL-134415-A0 (IL)
Title: Improvements relating to injection devices
IPC: A61J3/00
Filed: 1998-08-20
Abstract: An injection device is disposable, and is designed to have a reusable firing mechanism fitted to its rear end. A syringe carrier within the barrel of the device is initially locked in a position with the needle of the syringe retracted by a locking element inserted laterally through the barrel. This element also holds an axially movable connector to which the firing mechanism connects. The device is made operable by removal of the locking element, and after use a return spring ensures that neither the syringe carrier nor the connector assume positions where the locking element can be reinserted. An adaptor may be provided to facilitate preparing a syringe with a two-component dose, and for disposal after use the adaptor with an empty vial still attached can be fitted to the rear end of the injection device in place of the firing mechanism.
Patent IL-138128-A0 (IL)
Title: Delivery catheter
IPC: A61F2/95
Filed: 1999-04-01
Abstract: A medical catheter for the transvascular deployment of a collapsible medical device such as a filter has a tubular body formed by an inner tubular core surrounded by an outer thin-walled tube which is fixed to the core. The outer thin-walled tube extends outwardly beyond a distal end of the core to form a fixed thin-walled medical device embracing pod. The filter is carried on a guidewire which is slidably engagable within a central lumen of the core and the filter can be collapsed against the guidewire for loading within the pod. With the filter thus loaded within the pod the distal end of the catheter can be maneuvered through a patient's vascular system to a desired deployment site where the filter is discharged from the pod allowing the filter to expand within the blood vessel for use filtering blood flowing through the blood vessel.
Patent IL-138891-A0 (IL)
Title: Structures and methods for creating cavities in interior body regions
IPC: A61F2/44
Filed: 1999-04-06
Abstract: A tubular member is sized and configured to establish an access path to bone having an interior volume occupied, at least in part, by cancellous bone. The tubular member includes a distal end portion having at least one opening. A structure is sized and configured to be carried by the tubular member and controllably advanced through the at least one opening to define a cutting surface that projects outside the distal end portion. The cutting surface has a dimension capable of cutting cancellous bone in response to rotation of the tubular member within the cancellous bone.
Patent IL-145222-A0 (IL)
Title: Miniaturized cell array methods and apparatus for cell-based screening
IPC: G01N33/53
Filed: 2000-03-31
Abstract: The present invention describes novel methods for making a substrate for selective cell patterning, and the substrates themselves, wherein the method comprises contacting reactive hydroxyl groups on the surface of a substrate with a hydroxyl-reactive bifunctional molecule to form a monolayer, and using stencils to deposit cell repulsive or cell adhesive moieties in controlled locations on the cell culture substrate. Methods comprising selective differentiation of stem cells to create tissue specific and organ-specific cell substrates, as well as the cell substrates themselves are also provided.
Patent IL-147699-A0 (IL)
Title: Proton conducting material and method for preparing the same, and electrochemical device using the same
IPC: H01M12/00
Filed: 2000-07-19
Abstract: A proton conductor comprises a carbonaceous material essentially comprising a carbon, into which proton dissociating groups are introduced. In the proton conductor, protons migrate between the proton dissociating groups. Also, the ion conductivity of the proton conductor is larger than electron conductivity thereof. A carbon cluster such as a fullerene or a carbonaceous tubular material, or so-called carbon nano-tube, or a carbonaceous material which has diamond structures is used as a carbonaceous material. <IMAGE>
Patent IL-166708-A0 (IL)
Title: Flash-event detection with acoustic verification
Filed: 2005-02-07
Abstract: A system for identifying flash events including an optical imaging module (12) with one or more optical imaging array, the optical imaging module configured for monitoring a region of interest to identify a tentative flash event. The system further includes a ranging module (14) associated with the optical imaging module and configured to derive an estimated range to a location of the tentative flash event, and an acoustic verification module (16) associated with the ranging module and with one or more acoustic sensor. The acoustic verification module is configured to determine whether an acoustic event corresponding to the tentative flash event is detected within a time window derived from the estimated range, thereby classifying the tentative flash event as either a verified flash event or a rejected flash event.
Patent IL-172433-A0 (IL)
Title: Elicitor made from trigonella foenum graecum extracts for the treatment of plant pathogens, use thereof, and method for the production thereof
IPC: A01N65/20
Filed: 2005-12-07
Abstract: The method for preparing a novel elicitor or agent stimulating the defenses of plants against pathogens is applied to agronomically useful plants in order to control pathogens. The elicitor is prepared without extraction by a liquid from a dry product made of Trigonella foenum graecum seeds. The inventive method preferably includes the following steps: separating the germ fraction and cotyledon of the seed; grinding the fraction so as to obtain a powder; and solubilizing the powder in water, whereupon the obtained solution is sprayed onto the plant/s that is/are to be treated.
Patent IL-191796-A0 (IL)
Title: Combination of zd6474 and pemetrexed
Filed: 2008-05-28
Abstract: The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation, particularly a method for the treatment of a cancer, particularly a cancer involving a solid tumour, which comprises the administration of ZD6474 in combination with pemetrexed; to a pharmaceutical composition comprising ZD6474 and pemetrexed; to a combination product comprising ZD6474 and pemetrexed for use in a method of treatment of a human or animal body by therapy; to a kit comprising ZD6474 and pemetrexed; to the use of ZD6474 and pemetrexed in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation.
Patent IL-195302-A0 (IL)
Title: Position detector
Filed: 2008-11-16
Abstract: A position detector for detecting the position of a helicopter blade includes a sensor to generate a signal in dependence on the position of a helicopter blade with respect to the sensor, and a data processing module arranged to receive the signal from the sensor and generate an output indicative of the blade position from the received signal. The sensor includes a mask having a plurality of slits, a lens assembly, and light detector. The lens assembly has a field of view and directs incident light onto a focal plane of the lens assembly. The light detector detects the level of illumination passing through each of the slits in the mask and provides a signal indicative of the illumination level to the data processing module. The mask is located at the focal plane of the lens assembly and the slits formed in the mask are angularly divergent from one another.
Patent IL-198842-A0 (IL)
Title: Self sticking bibs and method of making
Filed: 2009-05-20
Abstract: A method of making bibs wherein an elongated web of absorbent paper is laminated with an elongated web of plastic to form a laminated web by embossing the absorbent paper and heat sealing the embossed area with the plastic film. The embossed areas are in the form of an array of spaced areas of a predetermined geometry. A stripe of an adhesive is applied along an edge of the laminated web of absorbent paper and plastic film on the plastic film side thereof. The stripe of adhesive is covered with a release tape. The laminated web is severed transversely at predetermined longitudinal intervals to form individual bibs, which are collected. In a further embodiment, the bib consists of a front side and a rear side, a top and a bottom and opposite side edges. The bib is made from a layer of plastic and two layers of absorbent paper.
Patent RO-132240-A0 (RO)
Title: Fiberglass composite material, process for manufacturing and testing the same to be used in container construction
Inventor: STANCIU ANCA ELENA
IPC: B32B27/04
Filed: 2017-05-30
Abstract: The invention relates to a composite material and to a process of using the same for the construction of a container. According to the invention, the material consists of 6 successive fiber layers arranged from inside to outside where: the first layer is made of fiberglass - short threads in epoxy resin matrix with a specific weight of 450 g/mand a thickness of 0.8...1 mm, the following four layers are each made of fiberglass - cloth in epoxy resin matrix with a specific weight of 800 g/mand a thickness of 3.2...3.6 mm and the last layer is made of fiberglass - short threads in epoxy resin matrix with a specific weight of 600g/mand a thickness of 1...1.3 mm. According to the invention, the process consists in applying the layers from inside to outside, on matrices corresponding to a container components, maintaining them for 14 days, after which the so-formed composite material is assembled as a container and is finished.
Patent RO-134482-A0 (RO)
Title: Fibrous support material of oleaginous plants with antioxidant properties, enriched with biologically active compounds obtained from wastes of aromatic and medicinal plants after extraction and methodfor preparing the same
Inventor: ORTAN ALINA - RUXANDRA - EUGENIA
IPC: A61K36/28
Filed: 2020-01-22
Abstract: The invention relates to a process for preparing a fibrous support material with antioxidant properties. According to the invention, the process consists in processing a fibrous material of oleaginous plants such as Silybum Marianum L., Helianthus Annuus L., Linum usitatissimum L., Carthamus tinctorius, by washing, drying for 24 hours at room temperature, mincing and treating with sulphuric acid solution 1%, and potassium hydroxide solution 1.7%, respectively, upon boiling, for 20 ... 30 min, filtering, washing with deionized water and acetone, drying and calcining at a temperature of 500 ... 550°C for 1 ... 2 h, to result in a filtrate which is enriched by immersion, without stirring, at a temperature of 25 ... 30°C, for 4 ... 5 h in hydroalcoholic extract of Origanum vulgare L., finally resulting in a bar-shaped material having an antioxidant activity of 200...300 μ g/ml gallic acid equivalent.
Patent RO-137124-A0 (RO)
Title: Device and process for evaluating the activity of photocatalytic products
Inventor: BUCURESTEANU RĂZVAN CĂTĂLIN
IPC: G01N21/63
Filed: 2022-07-20
Abstract: The invention relates to a device and a process for evaluating the activity of photocatalytic products by measuring in real time the degradation rate of a dye solution. According to the invention, the device consists of an enclosure where two systems of vats, illuminated each at the top by a LED source (1) with electromagnetic radiation in the UV-A or visible spectrum range, are inserted, the dye solution (3) and the test sample (6), respectively, being introduced into the vats and, at 1/3 of the height of the vats, on one of the walls, a laser diode (7) is mounted facing towards a photodiode (5) positioned on an opposite wall, which receives the light wave emitted by the diode (7) after passing through the dye solution, the photodiode (5) generating a signal that is taken by a system (4) for amplifying, processing and recording the signal in real time, the enclosure being hermetically sealed to prevent ambient light from entering.
Patent AU-2002950635-A0 (AU)
Title: Multiple directional wheel
IPC: B62B7/04
Filed: 2002-08-07
Abstract: A multiple directional wheel (10) including a frame (11) having a central hub (12) rotatable about a main axis and a plurality of roller supports (16) radially spaced from the central hub, a plurality of rollers evenly spaced around the circumference of the wheel (10) and rotatably mounted on the roller supports (16), the rollers rotatable about a corresponding plurality of roller axes aligned in the plane of the wheel and transverse to the main axis, the frame (11) is integrally formed in a first moulding process and the rollers are formed in place on the wheel (10) about the roller supports (16) in a separate process. In another embodiment there is disclosed a multiple directional wheel including a pair of opposed separately integrally formed first and second frames.
Patent LU-86784-A1 (LU)
Title: Laser-powered surface marking for sheet mill roller - produces spaced laser beam impart points on turning roller, and develops craters and rims in desired pattern
Inventor: BRAGARD ADOLPHE
IPC: C21D9/38
Filed: 1987-02-23
Abstract: The surface of a roller forming part of a sheet metal mill is irradiated by an interrupted laser beam which, as the roller is turned, develops a series of microcraters. The positioning of the craters is determined by the rate of turning of the roller, the rate of interruption of the laser beam, and the traverse rate of the laser as it moves from one end of the roller to the other. During the formation of each microcrater, a jet of reducing gas is directed obliquely at the roller surface to produce an associated ridge which partly surrounds the crater. The dimensions of the ridge are determined by the jet force and direction applied. In a subsequent phase, the ridge formed is re-melted by a subsidiary beam to ensure complete adhesion with the roller surface. The resulting pattern is transferred to any sheets rolled, improving their ductility for stamping and their receptivity to superimposed coats.
Patent LU-87137-A1 (LU)
Inventor: SCHLEICH JEAN-BAPTISTE
IPC: E04B5/29
Filed: 1988-02-19
Abstract: Composite girder formed by two T-shaped steel sections (2, 3) of comparable size juxtaposed so as to have the flanges in a single plane and fixed to the adjacent sides of their flanges by welding (17). A thick metal sheet (15) provided with hollowed-out regions (6) is fixed perpendicularly to the parallel webs (4, 5) of the said sections (2, 3). Hollowed-out regions (7) are provided in the webs of the sections (2, 3). The concrete, during its casting, penetrates via the hollowed-out regions (6, 7) into the space defined by the sections (2, 3) in order to thus form a concrete-steel composite girder. <IMAGE>
Patent LU-87282-A1 (LU)
Title: Refractory sleeve for rollers for transport - of high temperature metal products
Inventor: JACQUES PIRET
IPC: F27D3/02
Filed: 1988-07-15
Abstract: A composite roller for conveying hot metal has an inner metal structure supporting an outer refractory sleeve, and coaxial frustoconical contact surfaces between the structure and the ends of the sleeve with summit within the sleeve, each forming an angle with a radius of the sleeve whose tangent is equal to the ratio of the length of the sleeve to its mean dia.
Patent MA-26602-A1 (MA)
Inventor: KURT LANG
IPC: A61K35/12
Filed: 1999-02-01
Abstract: A pharmaceutical composition of a hedgehog protein which is characterized in that the hedgehog protein is bound to a hydrophilic carrier that is biocompatible and biodegradable wherein the carrier is a polymer which - binds the hedgehog protein as a negatively-charged carrier as a result of ionic interactions, - does not denature the hedgehog protein when it binds to the carrier, - contains at least 0.1 to 2 negatively-charged residues per monomer under neutral conditions, - contains the charge in the form of acidic groups, - has an average molecular weight of at least 50,000 Da - and contains no agarose reversibly and actively releases hedgehog proteins in vivo from a carrier in a delayed manner.
Patent MA-28323-A1 (MA)
Title: Ameliorations concernant la vaccination
Inventor: BEMBRIDGE GARY PETER
IPC: A61K39/39
Filed: 2006-03-27
Abstract: La présente invention concerne des vaccins dont l'acide nucléique est amélioré, des systèmes d'adjuvants, et des procédés pour l'élaboration de tels vaccins et systèmes d'adjuvants. Plus particulièrement, les vaccins à l'acide nucléique et les systèmes d'adjuvants de l'invention comprennent une combinaison d'une séquence de nucléotides codant le GM-CSF, ou certains de ses dérivés, et des agonistes des TLR (toll-like receptor), ou certains de leurs dérivés.
Patent MA-28163-A1 (MA)
Inventor: PIWONSKI TIMO
IPC: D03D15/567
Filed: 2006-05-15
Abstract: The invention relates to a double-layer woven fabric hose (10) that can be radially shrunk, comprising an upper and a lower fabric layer (8; 9). Said fabric layers (8; 9) are interconnected at their edges by binding warp threads (5). The hose also comprises weft threads (1; 2) consisting of a material with excellent shrinking qualities and warp threads (11; 12) consisting of a material with poor shrinking qualities. The binding warp threads (5) are configured as blocking threads with an alternating thick and thin structure.
Patent MA-37111-A1 (MA)
Inventor: SENDIDE KHALID ANISSI JAOUAD EL HASSOUNI MOHAMMED
IPC: C12N1/00
Filed: 2014-06-06
Abstract: Un processus est développé pour l'isolement et/ou la purification des acides nucléiques àpartir de tissus végétaux, comprenant l'utilisation d’un type de phosphate de calcium appelémonetite comme support chromatographique est présenté. Les procédés de l'inventionpermettent la séparation des polysaccharides, composésphénoliques, acides humiques etprotéines, des acides nucléiques. Le procédé comprend : (a) la préparation d’un extrait richeen acides nucléiques et, (b) l’utilisation du support de monetite synthétisé pour la purificationdes acides nucléiques. Par conséquence, fournir des préparations pures pour lesmanipulations de biologie moléculaire en aval.
Patent MA-38907-A1 (MA)
Title: Scooter ecologique
Inventor: HICHAM GOURGUE
IPC: B62K11/00
Filed: 2016-03-11
Abstract: L'invention concerne un moyen de locomotion qui travaillera uniquement avec l'énergie renouvelable spécifiquement l'énergie solaire. Un scooter électrique à base d'un ou plusieurspanneau photovoltaïque, comprenant un châssis pourvu d'un plateau sur lequel l'utilisateur setient debout, une roue avant montée de manière à permettre une commande de direction, etune roue arrière montée de manière pivotante sur la partie arrière du châssis.
Patent MA-41080-A1 (MA)
Title: Nouveaux procédés de fabrication de la gomme de caroube
Inventor: LAKKAB IMANE
Filed: 2017-09-25
Abstract: L’invention s’inscrit dans le domaine de l’industrie agroalimentaire de l’industrie pharmaceutique et cosmétique. Elle trouve application en industrie agroalimentaire particulièrement dans la production de stabilisants alimentaires extraits à partir des graines de la caroube appelés ‘’locust bean gum’’. L’invention concerne un procédé de décorticage de la graine de caroube par action couplée d’une enzyme et d’ultrasons, conduisant au ramollissement du tégument constituant l’enveloppe de ladite graine. Le détachement du tégument est rendu plus facile avec la préservation de l'intégrité structurelle et fonctionnelle des composés hydrolysés.