baber/WOPTO huggingface dataset:
Patent JP-2557605-B2 (JP)
IPC: C12P21/02
Filed: 1993-08-24
Granted: 1996-11-27
Abstract: An expression vector capable of expressing in a vertebrate host cell culture a desired protein and a secondary protein, which vector comprises a DNA sequence encoding for a desired protein and a DNA sequence encoding for a secondary protein wherein both said DNA sequences are operably linked to the same promoter sequence and separated by translational stop and start codons. 
<??>The secondary sequence provides for a convenient screening marker, both for transformants in general, and for transformants showing high expression levels for the primary sequence, as well as serving as a control device whereby the expression of a desired polypeptide can be regulated, most frequently enhanced.
Patent JP-2552590-B2 (JP)
IPC: G02B6/04
Filed: 1991-07-29
Granted: 1996-11-13
Abstract: An optical fibre transmission line is installed by first installing a conduit (11) having one or more bores (12) and subsequently inserting flexible, lightweight optical fibre members (14) containing the optical fibres (22, 32) into the bores (12). 
<??>The optical fibre members (14) are propelled by employing the fluid drag of air, or another suitable gas, passed at high velocity through the bores (12).
Patent JP-2788213-B2 (JP)
IPC: D01F/
Filed: 1995-09-18
Granted: 1998-08-20
Abstract: A discrete carbon fibril characterized by a substantially constant diameter between about 3.5 and about 70 nanometers, length greater than about 5 times the diameter and less than about 100 times the diameter, an outer region of multiple essentially continuous layers of ordered carbon atoms and a distinct inner core region. The invention further concerns a plurality of such fibrils. The fibrils of this invention may be produced by contacting for an appropriate period of time and at a suitable pressure a suitable metal-containing particle with a suitable gaseous, carbon-containing compound, at a temperature between about 850 DEG C and 1200 DEG C, or by treating discrete carbon fibrils, characterized by a length greater than about 100 times the diameter. Carbon fibrils may also be continuously produced by continuously contacting for an appropriate period of time at suitable conditions. Another aspect of the invention concerns a composition of matter comprising a carbon fiber or a carbon plate and a plurality of fibrils. Carbon fibrils and compositions of matter comprising carbon fibrils are useful in composites having a matrix of e.g., an organic polymer, an inorganic polymer or a metal. In specific embodiments, the fibrils or the compositions of matter may be used to reinforce a structural material, to enhance the electrical or thermal conductivity of a material, to increase the surface area of an electrode or capacitor plate, to provide a support for a catalyst, or to shield an object from electromagnetic radiation.
Patent JP-3390591-B2 (JP)
IPC: C07C69/76
Filed: 1995-10-13
Granted: 2003-03-24
Abstract: Conjugated polymers (I) contg. recurring units, having a 9,9'-spiro-bifluorene ring system, of formula (II) are new: A, B, C, D = 1-15 arylene, heteroarylene and/or vinylene gps. and these and the spiro-bifluorene ring system may be substd.; S = H or a substit., m, n = 0 or 1. Also claimed are: (a) the use of (I) as electroluminescent material; (b) electroluminescent material contg. (I); (c) prodn. of the material by applying a (I) film to a substrate; and (d) electroluminescent device with active layer(s), at least one or which contains (I).
Patent JP-H0730117-B2 (JP)
IPC: A61K38/00
Filed: 1987-11-02
Abstract: There is disclosed a method of producing a Factor VIII (AHF) containing fraction having a specific activity of at least 2.5 units of Factor VIII/mg protein as well as a portion of immunoglobulin G (IgG) of 10 mg/1000 units of Factor VIII at the most. Its risk of transmission of viral or bacterial infections is to be avoided or largely reduced. The method consists in that undesired proteins are at first precipitated from a Factor VIII (AHF) containing plasma fraction in the presence of SPS. The purified Factor VIII containing solution is treated with suitable salts or salt mixtures in order to obtain a Factor VIII containing precipitate. This precipitate is dissolved, lyophilized and finally heat-treated.
Patent JP-H0722519-B2 (JP)
IPC: G01N33/72
Filed: 1986-11-27
Abstract: 1. An agent for the detection and for the determination of peroxidase activity, containing in an aqueous solution a tetraalkylbenzidine or one of its salts, a peroxide or a system generating hydrogen peroxide, and a buffer substance, which agent contains penicillin or one of its breakdown products produced by acid hydrolysis.
Patent JP-2990436-B2 (JP)
IPC: F24F13/18
Filed: 1989-11-10
Granted: 1999-12-13
Abstract: The upper horizontal main frame member (1) of a roof window is designed as a hollow box-like structure comprising an inner ventilating compartment (12) which through a flow passage (18) provided with an adjustable damper (19) communicates with an outer ventilating compartment (13) with air exhausts (20, 21) positioned at both end walls (22, 23) of the box-like structure in the outer side of the roof. An improved aeration is thereby obtained which is also effectice when the window is provided with a rolling louver assembly (15). An exhaust fan (26) may be accommodated in the inner ventilating compartment (12) and the structure may be provided with separate remote-controlled motors for the exhaust fan ( 26), the rolling louver assembly (15) and the damper (19). In a large room installation with a number of windows more windows may, for instance by grouping, be operated from a single control unit.
Patent JP-3329775-B2 (JP)
IPC: C23C16/448
Filed: 1999-10-18
Granted: 2002-09-30
Abstract: A dynamic blending gas delivery system and method are disclosed. A blended gaseous mixture produced in accordance with the method is used in chemical vapor deposition tools or similar process tools. One embodiment is a multi-step method for processing a plurality of fluids to form a blended gaseous mixture and supplying the blended gaseous mixture to a distribution header from which the blended gaseous mixture is delivered to at least one tool. The first step is to supply a first fluid. The second step is to heat the first fluid to a temperature where at least some portion of the first fluid is a vapor. The third step is to superheat the vapor portion of the first fluid to a temperature sufficient to avoid condensation of the blended gaseous mixture delivered to the at least one tool. The fourth step is to supply a second fluid. The fifth step is to heat the second fluid to a temperature sufficient to avoid condensation of the superheated vapor portion of the first fluid when the superheated vapor portion comes in contact with the second fluid. The sixth step is to combine the heated second fluid and the superheated vapor portion of the first fluid to form a blended gaseous mixture having desired physical and chemical properties for chemical vapor deposition, epitaxial film growth, or a similar process. The final step is to deliver the blended gaseous mixture to the distribution header. In the preferred embodiment, the first fluid is trichlorosilane and the second fluid is hydrogen. <IMAGE>
Patent JP-3131178-B2 (JP)
IPC: C07D249/08
Filed: 1997-11-07
Granted: 2001-01-31
Abstract: A process is claimed for the preparation of products of formula (I): -R = H, or 1 - 10C alkyl, possibly substituted by one or more aryl, heteroaryl, hydroxy or alkenyl groups; by the reaction of hydrazine with a deficiency of carboxylic acid R-COOH, followed by elimination of the water of reaction and possibly water of dilution of the acid and hydrazine. Also claimed, are the reaction products, obtained with a high degree of purity.
Patent JP-3296648-B2 (JP)
IPC: G10L21/013
Filed: 1993-11-30
Granted: 2002-07-02
Abstract: Small discontinuities in digital sound data caused by a pitch control operation are processed by using a secondary FIR filter and smoothing the discontinuities. When lowering the key, the data value subject to the pitch down operation is moderately approximated to that of one sampling period before over a cycle of small discontinuity occurrence. when raising the key, the data value subject to the pitch up operation is moderately approximated to the current data value over a cycle of small discontinuity occurrence. By this method, the extent of the data discontinuity is greatly reduced. Large discontinuities for every segment are also processed by cross fading two converted data sequences which are produced from the input sound data and have different timings of large discontinuity occurrence, one data value being increased from its discontinuity point while the other data value is decreased from the same point in time. The weighting coefficients for the cross fade process vary in time along an upwardly convex polygonal line or a +E,fra 1/4+EE  cycle of a sine curve, thereby reducing the extent of the large discontinuity and avoiding the offset of the overlapped two data values.
Patent JP-2935845-B2 (JP)
IPC: B01F15/00
Filed: 1988-12-28
Granted: 1999-08-16
Abstract: Stirring of various products. 
<??>- The impeller according to the invention is characterised:
 - in that the blade segment (17):
 has a half-crescent shape and a width decreasing from the blade root (16),
 and is twisted, at least in its end part, by an angle ( gamma ) in the direction of the axis of rotation,
 - and in that the blade root (16) and the blade segment (17) assume, in cross-section, a triangular shape. 
<??>- Application to the preparation of industrial products. 
<IMAGE>
Patent JP-H0711022-B2 (JP)
IPC: F27B3/22
Filed: 1992-11-27
Abstract: To suppress dust and fumes in electric steel production in an electric melting furnace during the melting of iron products, such as raw iron, scrap iron directly reduced iron pellets and various alloying metals or mixtures thereof with widely fluctuating impurities, solid CO2 is passed into the melting vessel just before, during and after charging. In this way, the explosive combustion of the combustible constituents is prevented, since the oxygen is displaced during the charging step by the expanding gaseous CO2 being formed. <IMAGE>
Patent JP-H084627-B2 (JP)
IPC: A61M29/02
Filed: 1992-12-22
Abstract: A balloon catheter (10) having an expandable and collapsible elastic balloon (12) is shown, wherein the balloon (12) is reinforced by knitted fabric (23) such that the balloon (12) can not expand beyond a predetermined diameter regardless of the internal pressure applied to the balloon (12). The knitted construction (23) permits the balloon (12) to expand in diameter without shortening in length, and permits the balloon (12) to collapse smoothly without folds and wrinkles.
Patent JP-3605412-B2 (JP)
IPC: G01L1/00
Filed: 1994-05-12
Granted: 2004-12-22
Abstract: PCT No. PCT/GB94/01022 Sec. 371 Date Nov. 16, 1995 Sec. 102(e) Date Nov. 16, 1995 PCT Filed May 12, 1994 PCT Pub. No. WO94/28407 PCT Pub. Date Dec. 8, 1994The absolute values of biaxial stresses in a ferromagnetic material (16) are measured using a probe (12) which comprises an electromagnet (26), a sensor (32) for stress-induced magnetic anisotropy (SMA) and a sensor (30) for directional effective permeability (DEP). The DEP sensor (30) enables absolute values of stress to be determined; the SMA sensor (32) enables the directions of the principal stress axes to be accurately determined, and improves the accuracy of the stress measurements.
Patent JP-2588350-B2 (JP)
IPC: A01N37/06
Filed: 1991-10-29
Granted: 1997-03-05
Abstract: Disclosed is a herbicidal composition which combines two known active ingredients at concentrations of the individual active ingredients below the level generally necessary for the individual ingredients to exhibit herbicidal activity. The herbicidal ativity of the disclosed composition is greater than that of either of the individual active ingredients used alone. One of the active ingredients is a fatty acid based composition selected from caprylic acid, pelargonic acid, capric acid, undecanoic acid, 10-undecanoic acid, lauric acid, oleic acid, salts thereof and mixtures thereof. In addition, other fatty acid or fatty acid salt mixtures may be used, such as soybean fatty acid or coconut fatty acid. This component is present at a concentration range of about 0.1 to 3.0 percent by weight. The other active ingredient is a glyphosate-based herbicidal active ingredient, e.g., the isopropyl amine salt of N-(phosphonomethyl) glycine, present at about 0.08 to 1.0 percent by weight.
Patent JP-H066538-B2 (JP)
IPC: A61K49/00
Filed: 1985-03-28
Abstract: PCT No. PCT/NO85/00017 Sec. 371 Date Oct. 31, 1985 Sec. 102(e) Date Oct. 31, 1985 PCT Filed Mar. 28, 1985 PCT Pub. No. WO85/04330 PCT Pub. Date Oct. 10, 1985.Ferromagnetic particles, conveniently embedded in or coated by a biotolerable polymer and held in dispersion in a physiologically acceptable dispersion medium, may be used as contrast agents in nmr imaging for the production of images suitable for use in diagnosis. Unlike paramagnetic nmr contrast agents, ferromagnetic nmr contrast agents give particularly good contrast in the T2 dependent images.
Patent JP-3502093-B2 (JP)
IPC: C12N15/13
Filed: 1992-07-14
Granted: 2004-03-02
Abstract: This invention relates to the preparation of recombinant primate antibodies by DNA technology; Micro-RNA techniques for production of the same; recombinant non-human primate antibodies; formulations containing the same; the use of such antibodies in the prophylaxis and treatment of humans, and diagnostic uses of such antibodies.
Patent JP-3287842-B2 (JP)
IPC: A23L33/00
Filed: 1990-12-28
Granted: 2002-06-04
Abstract: The present invention relates to the treatment of an impaired human immune response or to reduction of the severity of degradation of the human immune response by the administration of arginine or ornithine, or a functional analog of arginine or ornithine, or mixtures thereof, to humans suffering from an impaired immune response or at risk of suffering an impaired immune response. Such treatment is provided by enterally administering compositions supplemented with arginine or ornithine, or functional analogs of arginine or ornithine, or parenterally administering amino acid solutions supplemented with arginine or ornithine, or functional analogs of arginine or ornithine, to the patient.
Patent JP-2701981-B2 (JP)
IPC: B08B15/02
Filed: 1992-08-17
Granted: 1998-01-21
Abstract: This invention relates to a fume hood controlling method and apparatus which reduces the amount of replacement air required to operate a fume hood by permitting the fume hood to operate at a relatively low face velocity in the absence of a containment affecting condition, but which is capable of detecting the occurrence of a containment affecting condition, such as the presence or movement of a user within a selected area of the face of the fume hood, and of increasing face velocity to a selected level in response to such detection. When the detected condition no longer exists, the control automatically returns the fume hood to the lower face velocity, preferably with a time delay. Maximum replacement air volume and minimum replacement air volume may also be controlled in response to such detection.
Patent JP-2538894-B2 (JP)
IPC: F16J15/16
Filed: 1986-09-09
Granted: 1996-10-02
Abstract: A sealing device between two cylindrical details (3, 4) consists of a sealing ring (1) and at least one sealing element (10, 11, 30, 37) arranged in a sealing groove (2) in one (3) of the details. The sealing ring is pre-stressed arranged against the other detail (4) for dynamic sealing against this detail and the sealing element is pre-stressed arranged against the sealing ring for sealing between the sealing ring and the sealing groove. The sealing ring (1) consists of a substantially setting-free, elastic and at least to a main part hard material giving a form-stiff cross section. Moreover, the sealing ring (1) is thin having such a small radial middle height (hm?) according to the formula hm? = A/b, where A is the cross section area of the sealing ring and b its radial width, that the sealing ring has maximum a surface pressure p against the other detail (4) which considering the material and surface structure of this detail and the lubricating qualities of the medium can be accepted according to the formula p = (2 . hm? . $g(D)d/d?2) . E, where E is the coefficient of elasticity of the sealing ring, d its diameter and $g(D)d its diametrical elastic deformation. Moreover, the radial height (h) of the sealing ring (1) along its side surfaces (6, 7) facing the gap (12) between the details (3, 4) is at least as large as the radial height of the gap.
Patent JP-3404047-B2 (JP)
IPC: C08F8/50
Filed: 1996-07-12
Granted: 2003-05-06
Abstract: A method for converting a polymer or oligomer derived from an ethylenically unsaturated monomer into alkanes or into a hydrocarbon fraction or a lower oligomer fraction by controlled hydrocracking, wherein the polymer or oligomer is exposed to a catalyst based on a metal hydride or an organometallic complex supported on a mineral carrier, the complex having at least one hydrocarbon ligand and optionally at least one hydride ligand, and the resulting mixture is reacted with hydrogen to cause catalytic hydrocracking of the polymer or oligomer. The polymer or oligomer is broken down into reclaimable products with a lower molecular weight for use, e.g., in the field of polymers, particularly controlled molecular weight polymers, fuels or lubricants.
Patent JP-3927233-B2 (JP)
IPC: A61K39/39
Filed: 1995-08-10
Granted: 2007-06-06
Abstract: Immunogenic polysaccharide-protein conjugates are generated which have an oxidized polysaccharide derived from the capsular polysaccharide of Streptococcal pneumniae and the pneumolysin protein of S. pneumoniae which is expressed recombinantly. The pneumolysin is not toxoided prior to conjugation with said oxidized polysaccharide. The immunogenic conjugates are used as vaccines to elicit antibody responses to the capsular polysaccharide of S. pneumoniae and to recombinant pneumolysin, and to immunize against S. pneumoniae-caused disease.
Patent JP-3194746-B2 (JP)
IPC: F25B35/04
Filed: 1993-08-13
Granted: 2001-08-06
Abstract: A chemisorption reaction process is carried out under conditions in which the volumetric expansion of the complex compound reaction product is restricted, and at half-cycle reaction periods of less than 30 minutes each, and/or in a reaction chamber having a maximum mean mass diffusion path length of less than about 15 mm, and/or a maximum heat diffusion path length of less than 1.5 mm.
Patent JP-4060881-B2 (JP)
IPC: A61K31/704
Filed: 1995-09-05
Granted: 2008-03-12
Abstract: PCT No. PCT/EP95/03480 Sec. 371 Date May 6, 1996 Sec. 102(e) Date May 6, 1996 PCT Filed Sep. 5, 1995 PCT Pub. No. WO96/07665 PCT Pub. Date Mar. 14, 1996The present invention provides the new use in the manufacture of a medicament for use in the treatment of amyloidosis of an anthracycline of formula A: wherein R1, R2, R3 and X are appropriate substituents. Novel compounds of the formula A, processes for their production and pharmaceutical compositions containing them are also described.
Patent JP-3762794-B2 (JP)
IPC: G03F7/32
Filed: 1997-08-22
Granted: 2006-04-05
Abstract: A bath for generating microstructures which is required in numerous fields of application of the microsystem technique and in microstructuring offers a less expensive alternative to known conventional approaches and disposal of the used bath may be carried out in a manner more environmentally friendly manner than in the previous methods for manufacture of microstructures. The bath includes at least one biogenic agent (in particular, an enzyme) which acts upon a preselectable thin layer.
Patent JP-2922953-B2 (JP)
IPC: B29C48/92
Filed: 1989-10-17
Granted: 1999-07-26
Abstract: Dimensionally stable alkenyl aromatic thermoplastic synthetic resinous elongate foam bodies having closed noninterconnecting gas-containing cells having an average cell size of 0.05 to 2.0 millimeters, a minimum cross-sectional dimension of at least 0.25 inch, a cross-sectional area of at least 8 square inches, a water vapor permeability not greater than 1.8 per inch, a density of from 1.0 to 5.0 pounds per cubic foot (16 to 80 g/l), and an absolute dimensional stability of less than 4 percent in any direction when measured by the test designated ASTM D2126/C578 are prepared using 1,1-difluoro-1-chloroethane as a blowing agent and extruding at controlled temperatures.
Patent JP-3898219-B2 (JP)
IPC: A61P43/00
Filed: 1994-10-28
Granted: 2007-03-28
Abstract: PCT No. PCT/DK94/00407 Sec. 371 Date Nov. 27, 1996 Sec. 102(e) Date Nov. 27, 1996 PCT Filed Oct. 28, 1994 PCT Pub. No. WO95/12591 PCT Pub. Date May 11, 1995The present invention relates to phenylindole compounds of formula I:    <IMAGE>  (I)  related to atypical neuroleptic sertindole.
Patent JP-2938973-B2 (JP)
IPC: G01N21/55
Filed: 1994-01-05
Granted: 1999-08-25
Abstract: There is disclosed fiber optic sensor which detects a sample in contact with the sensor by surface plasmon resonance (SPR) measurements, as well as methods and apparatus relating thereto. The fiber optic SPR sensor of this invention employs a limited range of incident angles and uses incident light having multiple wavelengths. In preferred embodiments, both an in-line transmission-based fiber optic SPR sensor and a terminated reflection-based fiber optic SPR sensor are disclosed. The fiber optic SPR sensor includes a surface plasmon supporting metal layer in contact with an exposed portion of the optical fiber core, and may optionally contain one or more additional layers deposited on the surface plasmon supporting metal layer. In further embodiments, methods are disclosed for detecting a sample by contacting the sample with the fiber optic SPR sensor of this invention, as well as sensing apparatus which contain the fiber optic SPR sensor in combination with a source of electromagnetic radiation of multiple wavelengths and a detection device.
Patent JP-4381476-B2 (JP)
IPC: A61K38/00
Filed: 1993-04-07
Granted: 2009-12-09
Abstract: A human gene has been discovered which is genetically altered in human tumor cells. The genetic alteration is gene amplification and leads to a corresponding increase in gene products. Detecting that the gene, designated hMDM2, has become amplified or detecting increased expression of gene products is diagnostic of tumorigenesis. Human MD2 protein binds to human p53 and allows the cell to escape from p53-regulated growth.
Patent JP-3394538-B2 (JP)
IPC: B01D27/10
Filed: 1993-12-02
Granted: 2003-04-07
Abstract: PCT No. PCT/EP93/03394 Sec. 371 Date Sep. 21, 1995 Sec. 102(e) Date Sep. 21, 1995 PCT Filed Dec. 2, 1993 PCT Pub. No. WO94/22548 PCT Pub. Date Oct. 13, 1994A filter device has a housing with connections for a fluid and can be secured to a filter pot. The filter has a filter element secured by a holder. A closure prevents the undesired leakage of fluid. The closure has two sealing plates with at least partly bound openings in mutually staggered array in two different planes. The openings can be mutually moved under the effect of a power store for closing or opening the openings. As the filter pot is moved further away from the housing, the closure gradually seals at least one of the connections and/or the filter pot off from the environment. The filter device has a universally usable closure which can be economically produced, requires little space inside the device and operates reliable.