baber/WOPTO huggingface dataset:
Patent EP-4011870-A1 (EP)
Inventor: WROBEL JAY EDWARD
IPC: C07D417/12
Filed: 2016-02-26
Abstract: Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process.
Patent EP-4012891-A1 (EP)
Inventor: BOIRLAUD MATTHIEU
IPC: H02K1/20
Filed: 2021-11-29
Abstract: Stator (1) de machine électrique tournante, comportant :- une culasse (2) comportant un empilement de tôles magnétiques (3), et- au moins un dissipateur thermique (10) rapporté sur la surface extérieure (4) de la culasse (2),le stator (1) comportant au moins un conduit (5) de refroidissement ménagé dans l'empilement de tôles magnétiques (3) de la culasse (2) et/ou dans ledit au moins un dissipateur thermique (10).
Patent EP-4187783-A1 (EP)
Inventor: HOOGZAAD GIAN
IPC: H03F3/19
Filed: 2021-11-30
Abstract: A circuit comprising: an input terminal; a first amplifier (304) coupled to the input terminal of the circuit to receive an input signal; a first inductor (310) having a first terminal coupled to the input terminal and a second terminal configured to be coupled to the ground terminal, wherein the first inductor (310) is arranged with a second inductor (313) and configured to magnetically couple therewith, wherein said second inductor (313) is coupled to the first amplifier (304) and is configured to sense a current through the first amplifier (304).
Patent EP-4011781-A1 (EP)
Title: Cockpit door security system
Inventor: MATHIEU MARK
IPC: B64C1/14
Filed: 2021-12-08
Abstract: There is provided a system for securing a cockpit from a cabin. A lavatory door (12) has a locking mechanism provided thereon. A latching mechanism is provided on an adjacent structure (14) across an aisle from the lavatory. The locking mechanism is compatible with the latching mechanism to secure the lavatory door (12) in an open position, thereby forming a secure area for entering from the cockpit.
Patent EP-4117171-A1 (EP)
Inventor: CALVENTE CORDON PABLO
IPC: H02P9/00
Filed: 2021-07-06
Abstract: A method for computer-implemented controlling a doubly-fed electric machine, where stator windings of a stator are directly connected to an electrical grid and where rotor windings of a rotor are connected to the electrical grid via a power conversion system, comprising an AC-to-DC converter and a DC-to-AC converter and being adapted to control a rotor current, the method comprising obtaining a rotational speed of the machine; determining, whether the obtained rotational speed is within a predetermined operational speed range around the synchronous speed; and if it is determined that the obtained rotational speed is within the predetermined operational speed range, controlling the AC-to-DC converter of the power conversion system to force injection of a stator reactive power to create a harmonic at a frequency different than a rated frequency of the machine; and controlling the DC-to-AC converter of the power conversion system to compensate the created stator reactive power and the harmonic.
Patent EP-4103443-A1 (EP)
Inventor: SCHULZ JÖRN
IPC: B61G5/08
Filed: 2021-01-22
Abstract: Die Erfindung betrifft eine automatische Luftkupplung für ein Schienenfahrzeug, mit einem Mundstück zum Ankuppeln der Luftkupplung an eine gegengleiche Luftkupplung; mit einem Druckluftstutzen zum Anschließen der Luftkupplung an ein Schienenfahrzeugdruckluftsystem; mit einem Strömungskanal, der das Mundstück druckluftleitend mit dem Druckluftstutzen verbindet; mit einem im Strömungskanal angeordneten Ventil, das einen Ventilkörper aufweist, der betätigbar ist, um den Strömungskanal wahlweise abzusperren und freizugeben; mit einem Ventilantrieb, der zur Betätigung des Ventilkörpers an diesem angreift, um den Strömungskanal wahlweise abzusperren und freizugeben. Die erfindungsgemäße automatische Luftkupplung dadurch gekennzeichnet, dass der Ventilkörper als Quetschrohr ausgeführt ist, welches zumindest einen Abschnitt des Strömungskanals umschließt und in einer Schließstellung des Ventilantriebs vom Ventilantrieb zusammengedrückt wird und den Strömungskanal abschnürend verschließt und in einer Öffnungsstellung des Ventilantriebs den Strömungskanal freigibt.
Patent EP-4088441-A1 (EP)
Inventor: PANDEY MANOJ
IPC: H04L12/46
Filed: 2021-01-07
Abstract: .This disclosure describes methods of operating a leaf node device, such as a switch device, connected to a switch fabric of a network. The leaf node device receives, from another leaf node device via the switch fabric, an indication of a secure route to a host device. In response to receiving the indication of the secure route, the leaf node device creates or updates a routing entry for the host device in a routing information base of the leaf node device and creates or updates an entry for the host device in a Dynamic Host Configuration Protocol (DHCP) snoop database of the leaf node device. The leaf node may thereby communicate with the host device that is attached to the leaf node device as a result of moving from the other leaf node device.
Patent EP-4121714-A1 (EP)
Inventor: GRIFFITHS OWAIN STEPHEN WILLIAM
IPC: F42B12/32
Filed: 2021-02-17
Abstract: A casing for a fragmentation weapon has a fragmentation layer 1 of preformed fragments 3 slidably fitted within preformed cells 6 of a lattice 2 sandwiched between an inner casing layer 4 and outer casing layer 5. The casing is particularly suited to use in fragmentation weapons and warheads. Upon detonation of the weapon, the preformed fragments 3 can freely separate from their cells 6 without being attached to the lattice 2 or other fragments 3.
Patent EP-4118860-A1 (EP)
Inventor: FUSS OLIVER
IPC: H04L12/28
Filed: 2021-02-18
Abstract: Es wird eine Vorrichtung (150) zur Steuerung des Zugriffs auf ein Elektrogerät (110) durch ein Anwendergerät (120) beschrieben. Die Vorrichtung (150) ist eingerichtet, Elektrogerät- Daten in Bezug auf eine Datenkommunikation des Elektrogeräts (110) zu ermitteln, und Anwendergerät-Daten in Bezug auf eine Datenkommunikation des Anwendergeräts (120) zu ermitteln. Des Weiteren ist die Vorrichtung (150) eingerichtet, auf Basis der Elektrogerät-Daten und auf Basis der Anwendergerät-Daten zu bestimmen, ob sich das Elektrogerät (110) und das Anwendergerät (120) in einem gemeinsamen lokalen Kommunikationsnetzwerk (131) befinden oder nicht. Die Vorrichtung (150) ist ferner eingerichtet, einen Zugriff des Anwendergeräts (120) auf das Elektrogerät (110) zu ermöglichen, wenn bestimmt wird, dass sich das Elektrogerät (110) und das Anwendergerät (120) in einem gemeinsamen lokalen Kommunikationsnetzwerk (131) befinden.
Patent EP-4121085-A1 (EP)
Title: Cyclotides in combination with kappa opioid receptor ligands for ms therapy
Inventor: GRUBER CHRISTIAN
IPC: C07K14/665
Filed: 2021-03-19
Abstract: The present invention relates to a pharmaceutical composition comprising a cyclotide and a ligand of the kappa opioid receptor (the kOR), or a combination thereof, for use in treating Multiple Sclerosis (MS), in remyelination, in improving CNS lesions, in preventing or reducing demyelination and/or CNS lesions, and/or in treating pain, in particular neuropathic pain and/or pain resulting from/coming along with MS. The present invention further relates to a combination of a cyclotide and a ligand of the kOR and to a pharmaceutical composition comprising said combination. The present invention further relates to a use of a cyclotide for reducing adverse effects of a ligand of the kOR and/or for increasing the potency and/or efficacy of a ligand of the kOR. Further, the present invention relates to a kit comprising a cyclotide and a ligand of the kOR. The present invention further relates to a pharmaceutical composition as part of a kit, wherein a comprised cyclotide and ligand of the kOR are for use in treating MS and related diseases and/or symptoms. The present invention further relates to a kit comprising a pharmaceutical composition comprising a cyclotide and a ligand of the kOR, wherein said pharmaceutical composition and/or said cyclotide and ligand of the kOR is/are for use in treating MS and related diseases and/or symptoms. The invention further relates to (a) novel Viola-type cyclotide(s).
Patent EP-4138671-A1 (EP)
Title: Visualisation de système vasculaire
Inventor: MERT AYDIN
IPC: A61B8/12
Filed: 2021-04-21
Abstract: Est divulgué, un procédé (100) pour visualiser une section du système vasculaire d'un patient (155) à l'aide d'un système de traitement d'image ultrasonore (3). Le procédé comprend la réception (103) des données ultrasonores générées par une sonde à ultrasons (10) étant déplacée sur une partie de l'anatomie du patient (150) contenant la section du système vasculaire du patient, lesdites données ultrasonores comprenant des données d'Image et des données Doppler ; la génération (107) d'images ultrasonores (170) à partir desdites données d'image, chaque image ultrasonore correspondant à une sous-section du système vasculaire du patient ayant un emplacement déterminé à l'intérieur du système vasculaire du patient et la combinaison (109) desdites images ultrasonores en une carte (180) de ladite section du système vasculaire du patient ; le traitement (111) des données Doppler reçues pour obtenir des caractéristiques de débit sanguin pour la section du système vasculaire du patient ; l'identification (113) de repères à l'intérieur de la section du système vasculaire du patient sur la base des caractéristiques de flux sanguin obtenues ; l'annotation (115) de ladite carte avec lesdites identifications de repères (181, 183) ; et la génération (117) d'un signal de sortie comprenant ladite carte annotée. Sont également divulgués, un produit programme informatique et un système de traitement d'image ultrasonore pour la mise en œuvre de ce procédé.
Patent EP-4150496-A1 (EP)
Inventor: DAVIES JOSEPH G
IPC: G06F11/36
Filed: 2021-03-25
Abstract: On-demand cloud-based staging environments can be rapidly created as mirrors of a production environment. By defaulting to the production environment's parameters but allowing the user to edit parameters before creating the new cloud-based staging environment, much of the work of creating staging environments can be automated. Users can create staging environments quickly and easily, so that environments can be used for a single project and dismissed, instead of having to maintain them and continuously synchronize them with changes in the production environment.
Patent EP-4136524-A1 (EP)
Inventor: PARKINSON PAUL
IPC: G06F8/60
Filed: 2021-04-14
Abstract: In accordance with an embodiment, described herein is a system and method for enabling use of a reactive messaging client in microservice environments. A microservices (e.g., Helidon) environment provides a development framework that enables a software developer to create and use microservices. In accordance with an embodiment, the system can include a reactive messaging API, for use with long-running activities or other types of transactions associated with microservices, which enables the system to additionally support various reactive messaging features, such as, for example, transaction processing, asynchronous messaging, reactive streams, or the use of messaging channels, in a microservices environment.
Patent EP-4171737-A1 (EP)
Inventor: MIANO DINO C
IPC: A61M5/142
Filed: 2021-05-06
Abstract: Provided are methods for clinical treatment of complement-associated conditions comprising administering to the patient an anti-C5 antibody, or antigen binding fragment thereof, wherein the anti-C5 antibody, or antigen binding fragment thereof, is administered (or is for administration) subcutaneously according to a particular clinical dosage regimen (i.e., at a particular dose amount and according to a specific dosing schedule). In one embodiment, the patient has previously been treated with eculizumab (SOLIRIS®) or ravulizumab (ULTOMIRIS ®); particularly intravenously administered SOLIRIS ® or ULTOMIRIS ®.
Patent EP-4172235-A1 (EP)
Title: Polyisocyanurathartschaumstoff mit hoher druckfestigkeit, geringer wärmeleitfähigkeit und hoher oberflächengüte
Inventor: KALUSCHKE TOBIAS
IPC: C08G18/40
Filed: 2021-06-23
Abstract: Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von Polyisocyanurathartschaumstoffen, bei dem man (a) aromatisches Polyisocyanat, (b) gegenüber Isocyanatgruppen reaktive Verbindungen, enthaltend mindestens ein Polyetherol (b1) und/oder Polyesterol (b2), wobei der zahlenmittlere Gehalt an mit Isocyanat reaktiven Wasserstoffatomen der Komponente (b1) und (b2) mindestens 1,7 beträgt, (c) Katalysator, (d) Treibmittel, (e) Flammschutzmittel (f) gegebenenfalls Hilfs- und Zusatzstoffe und (g) gegebenenfalls Verbindungen mit aliphatischen, hydrophoben Gruppen, die nicht unter die Definition der Verbindungen (a) bis (f) fallen, zu einer Reaktionsmischung vermischt und zum Polyisocyanurathartschaumstoff aushärten lässt, wobei Treibmittel (d) mindestens eine aliphatische, halogenierte Kohlenwasserstoffverbindung (d1), aufgebaut aus 2 bis 5 Kohlenstoffatomen, mindestens einem Wasserstoffatom und mindestens einem Fluor und/oder Chloratom und die Verbindung (d1) mindestens eine Kohlenstoff-Kohlenstoff-Doppelbindung enthält, und eine Kohlenwasserstoffverbindung mit 4 bis 8 Kohlenstoffatomen (d2) enthält und der molare Anteil von halogenierter Kohlenwasserstoffverbindung (d1) zwischen 20 und 60 mol% und der molare Anteil von Kohlenwasserstoffverbindung (d2) zwischen 40 und 80 mol-%, jeweils bezogen auf den Gesamtgehalt der Treibmittel (d1) und (d2), beträgt, und die Komponenten (b) bis (f) Verbindungen mit aliphatischen, hydrophoben Gruppen enthalten können und der Gehalt an aliphatischen, hydrophoben Gruppen, bezogen auf das Gesamtgewicht der Komponenten (b) bis (g), maximal 4,0 Gew.-% beträgt und die Vermischung zur Reaktionsmischung bei einem Isocyanatindex von mindestens 240 erfolgt. Weiter betrifft die vorliegende Erfindung einen Polyisocyanurathartschaumstoff, erhältlich nach einem erfindungsgemäßen Verfahren.
Patent EP-4169182-A1 (EP)
Inventor: ANDERSSON MICHAEL
IPC: H04J3/06
Filed: 2021-06-18
Abstract: L'invention concerne un procédé indépendant GNSS pour une compensation d'erreur de retard asymétrique pour minimiser un biais de différence de temps lors de l'utilisation d'un transfert de temps bidirectionnel dans un réseau de communication. Le procédé comprend l'établissement d'un chemin virtuel bidirectionnel comprenant au moins un chemin de liaison, LP1- LP4, sur le réseau pour une communication entre un premier nœud A et un second nœud B en envoyant un flux de données bidirectionnel sur le chemin virtuel et en utilisant des profils de liaison précédemment stockés associés à un facteur de correction de retard ou un chemin virtuel calibré ou une horloge locale stable en mode de maintien pour fournir un nouveau facteur de correction de retard afin de minimiser un biais de différence de temps dans le temps local dans le second nœud.
Patent EP-4165489-A1 (EP)
Title: Recherche visuelle pour application de lancement
Inventor: EIRINBERG DYLAN SHANE
IPC: G06F3/00
Filed: 2021-06-09
Abstract: Les systèmes et les procédés selon l'invention accèdent à un identifiant visuel, effectuent une recherche visuelle de l'identifiant visuel, en réponse à la réalisation de la recherche visuelle de l'identifiant visuel, provoquent la présentation d'un menu d'application à l'intérieur d'une interface utilisateur graphique d'un dispositif informatique, reçoivent une sélection d'un premier élément d'interface utilisateur dans le menu d'application, et en réponse à la réception de la sélection, exécutent l'application informatique.
Patent EP-3925456-A1 (EP)
Inventor: KIM YOUNG SIN
IPC: A24B15/28
Filed: 2021-03-08
Abstract: Provided herein are a coating composition of a low ignition propensity cigarette paper, a smoking article using the same, and a method of manufacturing the low ignition propensity cigarette paper. The coating composition of the low ignition propensity cigarette paper according to some embodiments of the present disclosure includes Arabic gum, ethanol, water, and fructo-oligosaccharide. Fructo-oligosaccharide may remarkably delay the aging speed of the coating composition and block even fine pores so that the ignition propensity of the coating composition is significantly reduced.
Patent EP-4092111-A1 (EP)
Inventor: SHIN EUN JI
IPC: C12N15/11
Filed: 2021-01-14
Abstract: The present application relates to cells having high adaptability under hypoxic conditions and to a preparation method therefor. Particularly, the present disclosure provides cells having high adaptability under hypoxic conditions, the cells including at least one engineered gene having an indel within a wild-type gene selected from the group consisting of HIF1AN, HIF3A, PHD2, TLR4 and PAI1. In addition, the present disclosure provides, as a method for preparing cells having high adaptability under hypoxic conditions, a gene editing method including introducing a CRISPR/Cas9 system into cells.
Patent EP-4093424-A1 (EP)
Inventor: MENTAK KHALID
IPC: A61K38/17
Filed: 2021-01-21
Abstract: L'invention concerne des compositions de protéines, qui comprennent des protéines de faible poids moléculaire, sont insolubles dans l'eau et ont des propriétés non hygroscopiques, des procédés de traitement de maladies ou d'états à l'aide de telles compositions, et des procédés d'inhibition de l'enzyme de conversion de l'angiotensine 1 (ECA) à l'aide de celle-ci.
Patent EP-4182524-A1 (EP)
Inventor: KING EDWARD
IPC: E05B47/02
Filed: 2021-07-19
Abstract: A smart lock for securing a closure is provided. The smart lock comprises: a drive train for actuating a lock mechanism between an unlocked positon and a locked position; an actuator arranged to drive the drive train to actuate the lock mechanism; a position sensor arranged to output a location signal indicative of a position of the drive train; a manual actuator arranged to drive the drive train to actuate the lock mechanism; and a movement sensor arranged to output a movement signal in response to movement of the manual actuator. The movement sensor is arranged to draw less power than the position sensor. The smart lock further comprises a processor configured to: a. detect the movement signal; and b. monitor the location signal in response to the detection of the movement signal.
Patent EP-4189486-A1 (EP)
Inventor: KUBO MASAHIKO
IPC: G03F7/004
Filed: 2021-07-26
Abstract: L'invention concerne un procédé d'utilisation d'une composition comprenant un ester d'acide carboxylique (A) ayant une certaine structure pour réduire l'onde stationnaire dans un processus de lithographie.
Patent EP-4181787-A1 (EP)
Inventor: DEMENSCHONOK FILIPP
IPC: A61B5/256
Filed: 2021-06-25
Abstract: The disclosed biopotential measurement device may include a biopotential measurement circuit and a right leg drive ("RLD") circuit coupled to the biopotential measurement circuit. The device may also include electrodes coupled to the biopotential measurement circuit and a chassis housing the biopotential measurement circuit and the RLD circuit. The chassis may include a conductive portion, coupled to the RLD circuit, that may serve as an RLD electrode for the RLD circuit. Various other methods, systems, and computer-readable media are also disclosed.
Patent EP-4150853-A1 (EP)
Inventor: PAILLIER PASCAL GILBERT YVES
IPC: H04L9/00
Filed: 2021-05-14
Abstract: L'invention porte sur un procédé cryptographique et ses variantes à base de chiffrement homomorphe permettant l'évaluation de fonctions à valeurs réelles sur des données chiffrées, afin de permettre de réaliser plus largement et efficacement des traitements homomorphes sur des données chiffrées.
Patent EP-4108101-A1 (EP)
Inventor: Teramoto yuki
IPC: A23G9/00
Filed: 2021-02-18
Abstract: Produced in an ice that can be added to water or drink to improve the flavor thereof. Provided is a mineral-containing composition containing potassium ions the concentration of which is the highest of the metal ions present in the mineral-containing composition.
Patent EP-4114995-A1 (EP)
Title: Duplex hardened cage pilot surface for bearing ring
Inventor: DE JONG RICK
IPC: C21D9/40
Filed: 2021-02-12
Abstract: A method of forming a bearing ring having improved hardness is disclosed herein. The method generally includes a duplex hardening process in which the bearing ring is first subjected to a heat treatment. After the heat treatment process, the bearing ring undergoes a nitriding treatment in predetermined portions, including at least a raceway and a cage pilot surface.
Patent EP-4114544-A1 (EP)
Inventor: NOWAK BRIAN J
IPC: B01D3/22
Filed: 2021-03-01
Abstract: L'invention concerne des plateaux ayant une capacité et un rendement accrus. Les plateaux ont une plate-forme et des espaces annulaires s'étendant à travers la plate-forme. Il y a une pluralité de promoteurs de bulles sur la plate-forme. Chaque promoteur de bulles définit une zone sur la plate-forme, et la zone a une ouverture dans la plate-forme. L'ouverture est positionnée adjacente à un support solide pour le plateau. Les promoteurs de bulles présentent des zones à travers lesquelles de la vapeur peut passer, transformant des zones bloquées du plateau en zones actives. L'invention concerne également des colonnes de transfert de masse contenant les plateaux.
Patent EP-4118040-A1 (EP)
Title: Subsea desalination system for shallow water
Inventor: TAYEBI DAVOUD
IPC: C02F1/26
Filed: 2021-03-10
Abstract: The present invention relates to shallow water subsea desalination system with a subsea desalination template (20) located on a seabed. A retrievable subsea RO-module (4) is located in a subsea RO-module zone (23) of the subsea desalination template (20) and is connected to a RO-module connection. A seawater booster pump assembly (1) includes a seawater inlet (7) and an outlet in fluid connection with a seawater inlet side of the RO-cartridge assembly. A retrievable subsea booster module (2) includes the seawater booster pump assembly (1). A pressure regulator (11) is in fluid connection with a retentate side of the least one retrievable subsea RO-module (4).
Patent EP-4134163-A1 (EP)
Title: Method for producing metal catalyst having inorganic film deposited thereon by means of ald process, and metal catalyst having improved activity according thereto
Inventor: CHO YOUNG JIN
IPC: C23C16/40
Filed: 2021-03-31
Abstract: The present invention relates to a method for producing a metal catalyst having an inorganic film deposited thereon by means of an atomic layer deposition (ALD) process, and to a metal catalyst according thereto. More specifically, the method includes a step of inducing selective adsorption of reactants to a portion having a low coordination number on the surface of the catalyst in the ALD process, thereby being intended to induce interaction between the catalyst and an inorganic film layer and maximally secure active sites of the catalyst.
Patent EP-4221722-A1 (EP)
Inventor: PUSKÁS ISTVÁN
IPC: A61K31/724
Filed: 2021-09-29
Abstract: The present invention generally relates to use of single isomer chemically modified cyclodextrins, namely, S-(carboxyalkyl)-thio-cyclodextrin salts in medication used for the prevention or treatment of lysosomal storage diseases. More particularly, the present invention relates to isomer-pure, single isomer hexakis-S-(carboxyalkyl)-hexathio-alpha-cyclodextrin sodium salts, heptakis-S-(carboxyalkyl)-heptathio-beta-cyclodextrin sodium salts and octakis-S-(carboxyalkyl)-octathio-gamma-cyclodextrin sodium salts in medication used for the prevention or treatment of lysosomal storage diseases.