baber/WOPTO huggingface dataset:
Patent CA-2752262-A1 (CA)
Inventor: NEUBAUER PETER
IPC: C12N1/22
Filed: 2010-03-04
Abstract: The present invention is generally in the field of continuous and high-cell-density cultivation in laboratory- or large-scale liquid shaken cultures. More particularly it relates to a method of enzyme-based fed-batch (EnBase) for liquid microbial prokaryotic or eukaryotic cell cultivation having the possibility to manipulate the growth rate of the cultured organisms by a controlled enzymatic release of the growth-limiting substrate- monomer from substrate-polymers or substrate-oligomers.
Patent CA-2753657-A1 (CA)
Inventor: PATEL NITINCHANDRA
IPC: C07D417/04
Filed: 2010-03-18
Abstract: Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are useful as intermediates in the preparation of potent active agents for the treatment of hepatitis C virus (HCV) infection.
Patent CA-2754864-A1 (CA)
Title: Light emitting device and luminaire
Inventor: VAN GORKOM RAMON P
IPC: F21V14/04
Filed: 2010-03-08
Abstract: This invention relates to a light emitting device (100) having a movable collimating unit for adjusting the output direction of light being emitted from the light emitting device.    The light emitting device comprises a base unit (110), and a light output unit (120) which is engaged with the base unit. The light output unit comprises at least one light source (121) for emitting light. The light emitting device further comprises a movably arranged collimating unit (130) for adjusting the direction of the emitted light, which is arranged such that it encompasses a light output portion (125), which is arranged on the light output unit.
Patent CA-2755492-A1 (CA)
Inventor: SHALEV ALON
IPC: A61L31/14
Filed: 2009-03-19
Abstract: A retrievable, sustained release, solid dosage form is provided for implanting into cranial bony canals and for prolonged release of an anesthetic, whereby treating neurovascular conditions, such as migraine. The dosage comprises an anesthetic contained in a polymeric carrier, and a retrieval member, the anesthetic being gradually released from the carrier.
Patent CA-2757431-A1 (CA)
Title: Direct control of devices through a programmable controller using internet protocol
Inventor: SNIDE TODD A
IPC: G05B19/05
Filed: 2010-03-25
Abstract: Aspects of the invention support direct communication between a low-level device and a programmable controller over an automation bus in an industrial automation system for controlling and monitoring an industrial process. A leaf node device may include a low-level device. The leaf node device communicates directly with the programmable controller at the network layer, e.g., Internet Protocol (IP) based on an IP address contained in a signal so that the programmable controller may control the low-level device or receive status information about the low-level device. The industrial automation system may support a plurality of leaf node devices, which may be associated with different automation buses having different communication media. Signals between the programmable controller and the leaf node device may be directed with or without a switching element.
Patent CA-2757928-A1 (CA)
Title: Self-dispersing particles and methods for making and using the same
Inventor: SUJEETH PUTHALATH K
IPC: C07D251/42
Filed: 2010-04-07
Abstract: A method of modifying a particle that includes reacting a reactive compound having an X-[Y]n reactive group with a secondary compound N-S-ZM to form a substituted reactive intermediate [Y]a-X-(N-S-ZM)b, and reacting the particle with the substituted reactive intermediate [Y]a-X-(N-S-ZM)b to attach the substituted reactive intermediate to the surface of the particle to form a surface modified particle. The particle may comprise at least one of a dye particle, an inorganic pigment particle, an additive, or a combination thereof. X may be a sulfonyl, phosphoryl, or 1,3,5-triazinyl group. Y may be a halogen leaving group. N  may be a nucleophilic group. S may be an organic group. ZM may be an ionizable end group. Also, n is an integer between 1 and 3, b is an integer between 1 and 3, and a = n-b. When n is equal to or greater than b, and wherein if b is 2 or 3, each N-S-ZM can be the same or different.
Patent CA-2760061-A1 (CA)
Title: Diamino heterocyclic carboxamide compound
Inventor: SHIMADA ITSURO
IPC: A61K31/541
Filed: 2010-05-06
Abstract: Disclosed are a compound represented by formula (I) or a sale thereof; a kinase inhibitor for EML4-ALK fusion protein containing the compound; and use of the compound for the treatment of cancers. (In formula (I), -X- represents a group represented by formula (II) or formula (III); A represents -H, a halogen atom, a lower alkyl group, a cycloalkyl group or a lower alkenyl group; R1 represents a substituted phyenyl group, a (substituted) heterocyclic group or a (substituted) bicyclic fused ring; R2 represents a (substituted) cycloalkyl group, a (substituted) non-aromatic heterocyclic group, a (substituted) phenyl group, a (substituted) pyridyl group or a (substituted) lower alkyl group; and R3 represents -H or a lower alkyl group; or alternatively R2 and R3 may combine together to form a cyclic amino group.
Patent CA-2763598-A1 (CA)
Inventor: MISKIN MICHAEL
IPC: H05B37/02
Filed: 2010-05-28
Abstract: A single chip multi-voltage or multi-brightness LED lighting device having at least two LED circuits having at least two LEDs connected se.pi.es, and electrically unconnected in a parallel relationship, a forward operating d.pi.ve voltage of at least six volts and are monolithically integrated on a single substrate, configurable by means of connecting the circuits so as to provide optional operating voltage level and/or de-sired bnghtness level wherein the electrical connection at the LED packaging level when the single chips are integrated into the LED package Alternatively, the LED package may have external electrical contacts that match the integrated chips within Optionally allowable, the drive voltage level and/or the bnghtness level selectability may be passed on through to the exterior of the LED package and may be selected by the LED package user, the PCB assembly facility, or the end product manufacturer.
Patent CA-2763751-A1 (CA)
Title: Compact pendant sprinkler head
Inventor: FRANSON SCOTT T
IPC: A62C37/08
Filed: 2001-05-17
Abstract: A sprinkler head for a fire extinguishing system comprises a sprinkler body having an orifice, the orifice defining an inlet and an outlet; a body extension attached to the sprinkler body and having an extending section extending below the outlet of the sprinkler body; a retaining member positioned below the outlet and within the body extension, the retaining member mounted to be movable relative to the body extension and the sprinkler body; a deflector movable between an activated position and a storage position within the body extension and having at least one support arm projecting therefrom, the retaining member coupled to the at least one support arm at a fixed distance from the retaining member, the support arm movably disposed within the body extension, wherein the deflector and the retaining member are positioned within the body extension when in the storage position, and wherein the retaining member is comprises an annular ring having an outer periphery, the outer periphery having at least one notch formed therein, wherein the at least one support member has an upper section dimensioned for receipt by the at least one notch;  a sealing assembly configured to sealingly engage the outlet of the sprinkler body, the sealing assembly movable from a closed position wherein the sprinkler head is inactive to an open position wherein the sprinkler head is activated; and a trigger assembly carried by the body extension and operably connected with the sealing assembly and the deflector.
Patent CA-2763810-A1 (CA)
Title: Chemically modified subtilisin mutants
Inventor: JONES J BRYAN
IPC: C12N9/54
Filed: 1997-11-24
Abstract: Modified enzymes are provided in which at least one amino acid, such as asparagine, leucine, methionine or serine, of an enzyme is replaced with a cysteine and the thiol hydrogen is replaced with a substituent group providing a thiol side chain selected from the group consisting of: a) -SR1R2, wherein R1 is an alkyl and R2 is a charged or polar moiety; b) -SR3, wherein R3 is a substituted or unsubstituted phenyl; c) -SR4, wherein R4 is substituted or unsubstituted cyclohexyl;  d) -SR5, wherein R5 is C10-C15 alkyl; and e) -SR6 wherein R6 is a C1-6 alkyl.  Also, methods of producing the modified enzymes are provided, as well as detergent and feed additives and a composition for the treatment of a textile. A method for using the modified enzymes in organic synthesis is additionally provided. Further, modified enzymes having improved activity, altered pH profile and/or wash performance are provided.
Patent CA-2764166-A1 (CA)
Inventor: HANSEL JAN-GERD
IPC: C07F9/11
Filed: 2012-01-13
Abstract: The present invention relates to a process for preparing tetraalkyl bisphosphates by reacting tetrachlorobisphosphates with alcohols, neutralizing the resultant hydrogen chloride with a base, and isolating the salt formed in the neutralization from the reaction mixture as a concentrated aqueous solution.
Patent CA-2766790-A1 (CA)
Inventor: LU CHEN
IPC: D21H17/63
Filed: 2010-06-25
Abstract: Enhancement of papermaking drainage and retention properties of aqueous cellulosic suspensions used for production of paper or paper board with a retention/drainage additive system including high solids glyoxalated polyacrylamide polymers in combination with silicon-containing microparticles is described.
Patent CA-2768467-A1 (CA)
Title: Multi-port modular connector for implantable electrical stimulation systems and methods of making and using
Inventor: BRASE RANDALL LEE
IPC: A61N1/375
Filed: 2010-07-13
Abstract: A connector for an electrical stimulation system includes an assembly of individual contact modules arranged along a common axis. Each contact module includes a body having a seat and at least two insertion apertures. An aperture contact is associated with each of the insertion apertures and is configured and arranged to electrically couple to a terminal of an elongated member when the elongated member is inserted into the associated insertion aperture. A seal plate is disposed in each seat of an associated one of the contact modules such that the seal plate is sandwiched between adjacent contact modules. Each seal plate is configured and arranged to electrically isolate the aperture contacts of the associated contact module from the aperture contacts of the other contact modules.
Patent CA-2768705-A1 (CA)
Title: Ldpe for use as a blend component in shrinkage film applications
Inventor: KARJALA TERESA P
IPC: C08J5/18
Filed: 2010-08-04
Abstract: An ethylene-based polymer characterized as having a density from about 0.9 to about 0.94 grams per cubic centimeter, a molecular weight distribution (Mw/Mn) from about 4 to about 10, a melt index (I2) from about 0.05 to about 2 grams per 10 minutes, a gpcBR value greater than 0.05 as determined by a gpcBR Branching Index and a Y value greater than 0.4 is disclosed. This ethylene-based polymer is especially useful for blending with other polymers such as LLDPE. When converting the blends into film, especially shrink film, the film shows good optics, good shrink tension, high stiffness, high tensile modulus, and tensile strength. When this resin is blended at with a LLDPE on a blown film line, improvements are seen in haze, gloss, clarity, and MD and CD tear as compared to a comparative LDPE.
Patent CA-2769899-A1 (CA)
Inventor: EVANS ANDREW MICHAEL
IPC: G06F9/48
Filed: 2012-03-01
Abstract: An enhanced interrupt controller is provided which is able to receive both hardware-generated and software-generated request signals. Data associated with each received interrupt or request signal is stored in a storage unit within the enhanced interrupt controller in an order which depends on the priority level of the data and, for data of the same level of priority, on the chronological order of receipt. The enhanced interrupt controller instructs the processor, with which it is in communication, to read the stored data from the controller in the stored order ensuring that data of higher priority is read before data of lower priority. A method of routing hardware-generated and software-generated signals from an enhanced interrupt controller to a processor is also disclosed.
Patent CA-2771354-A1 (CA)
Title: Systems, apparatuses, and methods for treating wastewater
Inventor: HALEY JOHN W III
IPC: C12M1/10
Filed: 2010-10-13
Abstract: Systems, apparatuses, and methods of treating wastewater are provided. In some aspects, a container may be provided and may include a first member, a second member spaced apart from the first member, and media supported by and extending between the first and second members. An organism may be introduced into the container and wastewater may be introduced into the container for treatment. The media may be loop cord media. In other aspects, two containers may be provided and wastewater may be initially introduced into a first container for treatment, removed from the first container, and subsequently introduced into the second container for further treatment. A first species of organism may be present in the first container and a second species of organism may be present in the second container. Methods of using these containers are also provided.
Patent CA-2773468-A1 (CA)
Inventor: HERMANN ROBERT
IPC: G01N33/18
Filed: 2012-04-05
Abstract: The invention relates to a method and a device for determining the concentration of one or more oxidizing agents in an aqueous solution flowing in a main stream.  According to the method, a partial flow of the aqueous solution is diverted to a bypass, wherein the difference between the potential of the aqueous solution before and after at least partial and/or selective breakdown of any oxidizing agents present is measured in the bypass.  The device has a bypass for diverting and returning a partial flow of the aqueous solution, at least one elimination unit located in the bypass of the partial stream of aqueous solution through which the aqueous solution flows for at least partial and/or selective breakdown of the oxidizing agent(s), and two measuring electrodes for determining the difference between the potentials of the aqueous solution in the partial stream before and after it passes through the elimination unit.   The invention thus provides a reliable, easily implementable method and a corresponding device for determining the concentration of oxidizing agent in aqueous solutions.
Patent CA-2774118-A1 (CA)
Inventor: RIMKUS KATRIN
IPC: A61K45/06
Filed: 2010-09-13
Abstract: The present invention relates to a pharmaceutical composition comprising the active substance metformin in combination with one of the substances sitagliptin or vildaliptin. The present invention further relates to a method for producing said pharmaceutical composition.
Patent CA-2778250-A1 (CA)
Title: Hydrogen fluoride-hfc-254eb azeotrope and its uses
Inventor: KNAPP JEFFREY P
IPC: C07C17/386
Filed: 2010-10-12
Abstract: Described is a process for separating 1,1,1,2-tetrafluoropropane and hydrogen fluoride from a mixture comprising 1,1,1,2-tetrafluoropropane, 1,1,1,2,3-pentafluoropropane and hydrogen fluoride comprising: subjecting said 1,1,1,2-tetrafluoropropane, 1,1,1,2,3-pentafluoropropane and hydrogen fluoride mixture to a distillation step, forming a column distillate composition comprising an azeotropic or near-azeotropic composition of said 1,1,1,2-tetrafluoropropane and hydrogen fluoride, and a bottoms composition of 1,1,1,2,3-pentafluoropropane. The column distillate may optionally be made essentially free of 1,1,1,2,3-pentafluoropropane and the column bottoms composition may optionally be made essentially free of HF. Also described is a process for separating 1,1,1,2-tetrafluoropropane and hydrogen fluoride from a mixture of 1,1,1,2-tetrafluoropropane and hydrogen fluoride. Also described are azeotropic and azeotrope-like compositions comprising 1,1,1,2-tetrafluoropropane and hydrogen fluoride.
Patent CA-2779989-A1 (CA)
Title: Quinazoline compounds
Inventor: KALLANDER LARA S
IPC: A61K31/5377
Filed: 2010-11-01
Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, R4, R5, R6 and R7 are as defined herein, and methods of making and using the same.
Patent CA-2781893-A1 (CA)
Inventor: NOVAK WILLIAM J
IPC: C10G65/04
Filed: 2010-12-06
Abstract: Methods are provided for hydrotreating high nitrogen feeds with improved results for nitrogen removal, aromatic saturation, and/or sulfur removal. The method includes hydrotreating the feed with a supported hydrotreating catalyst followed by a bulk metal catalyst, the hydrotreated effluent of which can be suitable for use as a feed to an FCC reactor.
Patent CA-2785431-A1 (CA)
Title: Cleaved and phosphorylated crmp2 as blood marker of inflammatory diseases of the central nervous system
Inventor: GIRAUDON PASCALE
IPC: G01N33/68
Filed: 2009-07-16
Abstract: The present invention relates to a method for in vitro prognosis, diagnosis and/or monitoring of an inflammatory disease of the central nervous system in a subject, said method comprising detecting, in a sample of cells of the immune system from the subject, the presence of a Collapsin Response Mediator Protein 2 (CRMP2) which is phosphorylated on tyrosine 479 (Y479), and optionally further phosphorylated on serine 465 (S465), wherein the detection of the presence of Y479-phosphorylated CRMP2, which is optionally further phosphorylated on serine 465, is indicative of an inflammatory disease of the central nervous system.
Patent CA-2785464-A1 (CA)
Title: Ceramic particles with controlled pore and/or microsphere placement and/or size and method of making same
Inventor: WU SHANGHUA
IPC: C04B35/01
Filed: 2010-12-23
Abstract: The present invention relates to lightweight high strength microsphere containing ceramic particles having controlled microsphere placement and/or size and microsphere morphology, which produces an improved balance of specific gravity and crush strength such that they can be used in applications such as proppants to prop open subterranean formation fractions. Proppant formulations are further disclosed which use one or more microsphere containing ceramic particles of the present invention. Methods to prop open subterranean formation fractions are further disclosed. In addition, other uses for the microsphere containing ceramic particles of the present invention are further disclosed, as well as methods of making the microsphere containing ceramic particles.
Patent CA-2786799-A1 (CA)
Inventor: BEATY TERRY
IPC: G01N33/487
Filed: 2011-01-27
Abstract: The present invention relates to a biosensor. The biosensor includes a support substrate, electrodes positioned on the support substrate, a spacer substrate positioned on the support substrate, and a cover positioned on the spacer substrate. The cover cooperates with the support substrate to define a capillary channel. The electrodes include at least one working electrode defining a working electrode area in the capillary channel. The working electrode is configured to minimize variation in the working electrode area in the capillary channel due to variations in the spacer substrate placement relative to the working electrode. The working electrode comprising a main body portion and at least one connecting portion.
Patent CA-2793243-A1 (CA)
Title: Adjustable chest drape
Inventor: CHUA MARK SPENCER G
IPC: A61B19/08
Filed: 2012-10-25
Abstract: An adjustable drape (100) is manufactured from a flexible fabric layer and has a front major face (201) and a rear major face (101). One or more wearer attachment devices (102,103) are disposed along the rear major face (101), while one or more adjustment devices (202,203) are disposed along the front major face (201). When the flexible fabric layer attached to the chest of a wearer (400), it is not visible from the behind the wearer (400). Accordingly, the adjustable drape (100) can be used to preserve patient dignity during advanced imaging procedures.
Patent CA-2794333-A1 (CA)
Inventor: KOBAL GERD
IPC: A24B15/30
Filed: 2011-03-28
Abstract: An orally-enjoyable tobacco product (10, 100) includes a portion of smokeless tobacco comprising an active ingredient. The active ingredient is selected from the group consisting of a mercaptan, camphor, borneol, isobomeol, bornyl acetate, isobornyl acetate, mono-bornyl succinate, mono-isobornyl succinate, mono-bornyl formate, and mono-isobornyl formate. The active ingredient is present in an amount effective to reduce or eliminate the sensory irritation arising from the smokeless tobacco. Also disclosed is a method of making such a product.
Patent CA-2795370-A1 (CA)
Inventor: MARTIN ROGER FRANCIS
IPC: A61P39/00
Filed: 2011-04-06
Abstract: The invention relates to novel compounds, processes for their preparation and their use in protecting biological materials from radiation damage (radioprotection). Preferred compounds of the invention are those of Formula (II), as follows: wherein W represents -N(R1R2) where R1 and R2 are not both hydrogen and where they may together form a 5, 6 or 7 membered ring structure, -NHN(R1R2), NHR3N(R1R2), -NHR3OR2, -N(R3)R3OR2, -N(R1)R3OR3OR3, OR3NR1R2, -OR3 or W represents piperidyl, piperazinyl, morpholinyl, thiomorpholinyl or diazepanyl each of which may be optionally substituted by C1 to C4 alkyl, C2 to C4 alkenyl, -N(CO)N(R1R2), -N(CO)OR1, -N(CO)OR3OH, -(CO)NR1R2, -R3(CO)NR1R2, -R3OR1, -OR1, -N(R1R2) OR -NH-; R1 and R2 are the or different and are selected from hydrogen, C1 to C4 alkyl or C2 to C4 alkenyl; group or chain; Z is the same or different and represents N or CH; Z' is the same or different and represents N or C; X represents CH, N or NH, where ?? is a double bond when X is CH or N and a single bond when X is NH; X' represents N or NH, wherein when X is CH or N X' is NH and wherein X and X' are different and further where ???is a double bond when X' is N and a single bond when X' is NH; Q represents H, alkoxyl, -NR1R2, F or Cl; Q1 is absent when Z' is N and when Z' is C it represents H, alkoxyl, -NR1R2, F or Cl; A represents a five to ten membered single or multiple ring structure with heterocyclic N or O located at the ortho position, said ring including optional double bonds, substitutions and/or other heteroatoms and pharmaceutically acceptable derivatives thereof.
Patent CA-2795688-A1 (CA)
Inventor: BROWN PATRICK W
IPC: A63G9/12
Filed: 2011-04-22
Abstract: A stand-on swing for suspension from a playset structure includes a platform member presenting an upper surface on which the user may stand. The swing also includes a pair of elongated, rigid suspension bars each presenting upper and lower ends. The bars are pivotally connectable to the structure adjacent the upper ends so as to depend therefrom, with the lower ends being spaced from the ground. The swing further includes a pair of lower pivot joints pivotally connecting the suspension bars to the platform member adjacent the lower ends thereof, with the platform member and bars being swingable in a fore-and-aft direction. The bars are bowed so as to present intermediate sections that are spaced further apart than the upper and lower ends. Further, the bars terminate above or generally at the platform member so that the lower ends are prevented from being spaced substantially downward beyond the platform member.
Patent CA-2796441-A1 (CA)
Inventor: SUEDA SATORU
IPC: C09D7/61
Filed: 2011-04-11
Abstract: The object of the present disclosure is to obtain a filler particle having stable insulation property, and a resin composition, grease and a coating composition comprising the same, respectively. Filler particles comprising a composite zinc oxide expressed by the following chemical formula (1): Zn x M y O    (1) in the formula, M is Mg, Co, Li, K, Na or Cu, and x+ny/2=1 when the valence of M is n.