baber/WOPTO huggingface dataset:
Patent HU-0001976-A3 (HU)
Title: Antiviral protease inhibitors and pharmaceutical compositions
IPC: A61K31/44
Filed: 1998-04-03
Abstract: Compounds of the formula  I :   
wherein: 
A' and A" are independently the same or different group of the formula  II :   
wherein:  R' is H, CH 3 , C(CH 3 ) 2 , -OR a , -N(R a ) 2 , -N(R a )OR a  or -DP  R''' is H or CH 3 ; R a  is H, C 1 -C 3  alkyl;  D is a bond, alkylene, -C(=O)-, -S(O)- or -S(O) 2 - ;  P is an optionally substituted, mono or bicyclic carbo- or heterocycle;  R" is H, any of the sidechains found in the natural amino acids, carboxacetamide, or a group (CH 2 ) n DP;  M is a bond or -C(=O)N(R''')-;  Q is absent, a bond, -CH(OH)- or -CH 2 -;  or R" together with Q , M and R' define an optionally substituted 5 or 6 membered carbo- or heterocyclic ring which is optionally fused with a further 5 or 6 membered carbo- or heterocyclic ring;  with the proviso that R' is -OR a , -N(R a ) 2 , -N(R a )OR a  or -DP, if M is a bond and Q is absent; X is H, OH, OCH 3 ;  Y is H, OH, OCH 3 , but X and Y are not both H;  Z' and Z" are independently -(CH 2 ) m P where P is as defined above;  n and m are independently 0,1 or 2;  and pharmaceutically acceptable salts and prodrugs thereof have utility as aspartyl protease inhibitors of HIV. They can be prepared in a facile two step synthesis from novel 2,5-di-O-benzyl-L-mannaro-1,4:6,3-dilactone intermediates.
Patent HU-0003394-A3 (HU)
Title: Pyrido[2,3-b][1,5]benzodiazepine derivatives, their use, process for their preparation and pharmaceutical compositions containing them
IPC: C07D498/04
Filed: 1998-07-24
Abstract: The present invention provides compounds of general formula (I): wherein W is O or NH, optionally substituted, as well as methods and pharmaceutical compositions utilising these compounds for the treatment of disorder which may be remedied or alleviated by vasopressin agonist activity, including diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, bleeding and coagulation disorders, or temporary delay of urination.
Patent HU-0102054-A3 (HU)
Title: Intraocular lens
IPC: A61F2/16
Filed: 1999-05-03
Abstract: Intraocular lens comprising a central optical body and haptics attached to or formed integrally with said optical body wherein the haptics are attached to the optical body via connecting members separating the haptic plane from the optical plane by a distance b which is at least half the thickness of the optical body.
Patent HU-0104076-A3 (HU)
Title: Safety system to prevent the functioning of a blender or food processor if the top its cup is not in place
IPC: A47J43/046
Filed: 1999-10-02
Abstract: The invention is related to an electrical appliance from the type blender of food processor, comprising a base including an electric motor, a container able to be removably secured on said base, said container having a cylindrical open top, a food processing tool mounted in the bottom of said container and able to be driven by said motor, a lid able to close said container, means for limiting axial movement of the lid, means for limiting rotational movement of the lid, a safety device including a pin mounted on the container and a switch mounted on the base, the lid including means for actuating the pin to operate the switch in order to enable motor operation when the lid occupies a closed operating position on the container, wherein a locking button is provided on the container, said button being able to actuate a lock able to bear against an abutment or to enter a notch, said notch or said abutment being provide on the lid, to lock the lid on the container in the closed operating position.
Patent HU-0105284-A3 (HU)
Title: Inhibitors for use in hemostasis and immune function
IPC: A61P9/00
Filed: 2000-02-17
Abstract: The invention provides uses for adipocyte complement related protein in the manufacture of pharmaceuticals for minimizing vascular occlusion, inducing vasodilation and enhancing the progression of wound healing in mammals. A preferred amino acid sequence for the adipocyte complement related protein is provided. The invention demonstrates particular utility in treating cases of vascular injury arising from surgery or trauma. <IMAGE>
Patent HU-0300652-A3 (HU)
Title: Pourable frying composition
IPC: A23D7/01
Filed: 2001-04-06
Abstract: Pourable frying products that comprise an ester of citric acid with a mono- or diglyceride show improved spattering behaviour.
Patent HU-0302056-A3 (HU)
Title: Armor-plating composite
IPC: B32B7/00
Filed: 2001-05-05
Abstract: A composite material for armor plating with improved multihit behavior includes at least: a front layer, facing the impact side and mounted on a first sub-layer, the front layer including a plurality of neighboring front-layer segments with form-fit contact between adjacent segments; a rear layer facing away from the impact side; and a supporting layer disposed between the front and rear layers. The supporting layer includes a plurality of supporting-layer segments, which present a surface parallel to the front layer whose area is the same as or less than the area of the front-layer segments parallel to the front layer.
Patent HU-9602070-A3 (HU)
Title: Equipment for forming lamphole
IPC: E03F5/02
Filed: 1996-07-26
Abstract: The mould casing (12) has sleeve inserts, and contains a core (14) one end side of which has a template (34) matching the shape of the channel in the base of the drainage shaft. The template has an outward protruding protuberance which has an outer surface matching the wall of the channel at the bottom of the shaft. The protuberance has a first part leading at its base into the surfaces for the gradient of the base of the shaft. A second curved part of the protuberance is saddle-shaped to match the gradient of the channel base and is detachably joined to the first part, the template has a circular rim and radially inwardly displaced edge fitting into the hollow cylindrical core.
Patent HU-9702461-A3 (HU)
Title: Cell adhesion inhibitors and pharmaceutical compns. contg. them
IPC: A61K31/00
Filed: 1996-01-18
Abstract: The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of using them for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. The compounds and pharmaceutical compositions of this invention can be used as therapeutic or prophylactic agents. They are particularly well-suited for treatment of many inflammatory and autoimmune diseases.
Patent HU-9903929-A3 (HU)
Title: Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines-and method of reducing tnf-alpha levels
IPC: A61P17/06
Filed: 1997-07-24
Abstract: 1. A 2,6-dioxopiperidine selected from the group consisting of 
( a ) a compound of the formula:   
in which: 
one of X and Y is C=O and the other of X and Y 
( i ) each of R 1 , R 2 , R 3 , and R 4 , independently of yl of 1 to 4 carbon atoms, or alkoxy of 1 to 4 carbon atoms or ( ii ) one of R 1 , R 2 , R 3 , and R 4  is -NHR 5  and the remaining of R 1 , R 2 , R 3 , and R 4  are hydrogen; 
R 5  is hydrogen, alkyl of 1 to 8 carbon atoms, or CO-R 7 -CH(R 10 )NR 8 R 9 ; 
R 6  is hydrogen, alkyl of 1 to 8 carbon atoms, benzo, chloro, or fluoro; 
R 7  is  m -phenylene or  p -phenylene or -(C  n  H 2 n  )- in which  n  has a value of 0 to 4; each of R 8  and R 9  taken independently of the other is hydrogen or alkyl of 1 to 8 carbon atoms, or R 8  and R 9  taken together are tetramethylene, pentamethylene, hexamethylene, or -CH 2 CH 2 XCH 2 CH 2 - in which X is -O-, -S- or -NH-; 
R 10  is hydrogen, alkyl of 1 to 8 carbon atoms, or phenyl; and  
( b ) the acid addition salts of said compounds which contain a nitrogen atom capable of being protonated.
Patent WO-0131099-A3 (WO)
Title: Procede et appareil correspondant pour la realisation en ligne des etapes d'etirage et d'ourdissage de monofilaments en polyamide
Inventor: PEZZOLI LUIGI
IPC: D04B21/00
Filed: 2000-10-27
Abstract: Cette invention se rapporte à un procédé et à un appareil servant à la réalisation en ligne des étapes d'étirage et d'ourdissage de fils monofilaments (10) en polyamide, ce procédé et cet appareil utilisant une première étape de prétensionnement (4-4a; 6-6a-6b) des fils monofilaments se dévidant à partir de bobines placées sur une cantre, par passage à travers un compensateur de tension pour ces fils, et une étape d'étirage sur plusieurs rouleaux (11-13, etc.) disposés en groupes, chaque groupe étant distant de l'autre. Chaque groupe de rouleaux est placé dans un séparateur-conteneur (7-9) et, à la sortie des fils de chaque groupe, on dispose un peigne guide-fil (18-18a-18b) et une barre d'ionisation (19) pour l'élimination des charges électrostatiques accumulées par les fils lors de leur mouvement de translation sur les rouleaux. La pluralité des fils traités simultanément forme un nombre d'environ 1200 fils maintenus espacés les uns des autres par une distance comprise entre 1,4 et 1,6 mm.
Patent WO-03079392-A3 (WO)
Title: Structure des electrodes et des elements phosphorescents d'un ecran a plasma
Inventor: SALTERS BART A
IPC: G09G3/298
Filed: 2003-03-17
Abstract: L'invention concerne un écran à plasma à courant alternatif (12) du type à décharge de surface, et plus particulièrement la structure des électrodes d'adressage (5) dudit écran et des éléments phosphorescents, ainsi qu'un dispositif à écran à plasma comprenant cet écran. Selon l'invention, une seule électrode d'adressage (5) est utilisée pour une colonne sur deux. Les électrodes de balayage (8) et les électrodes communes (7) peuvent comporter des parties transparentes (11). Ces parties (11) peuvent s'étendre sur une cellule sur deux, à la façon d'un damier. Dans un mode de réalisation préféré, les colonnes peuvent posséder des cellules (2) alternativement larges (15) et étroites (16). De plus, chaque cellule possède une cellule voisine de couleur identique sur la même électrode d'adressage mais dans une colonne et une rangée voisines. Le dispositif à écran à plasma comprend un circuit d'excitation (22) qui permet d'adresser simultanément les cellules voisines dans au moins un des sous-champs.
Patent WO-2004023286-A3 (WO)
Inventor: HARS LASZLO
IPC: H03K3/84
Filed: 2003-08-15
Abstract: A physical random number generator operates to generate a true random bit sequence while a linear feedback shift register and a clock collectively operate to provide a plurality of feedback random bit sequences. In operation, the linear feedback shift register periodically latches the feedback random bit sequences in response to a clock signal having a predetermined operating frequency from the clock. In latching the feedback random bit sequences, the linear feedback shift register includes a plurality of bi-stable latches for linearly shifting a mixed random bit sequence outputted by an XOR gate, which is combined with the true random bit sequence. A decimator receives a feedback random bit sequence and provides an output random bit sequence that is representative of a selective outputting of the feedback random bit sequence.
Patent WO-2004027597-A3 (WO)
Title: Réduction de quisquater améliorée
Inventor: HUBERT GERARDUS T M
IPC: G06F7/72
Filed: 2003-09-10
Abstract: Procédé et dispositif servant à calculer le produit P d'un premier nombre X et d'un deuxième nombre Y, modulo N. Y, qui est divisé en j mots présentant chacun des bits de longueur p, et comporte des bits de longueur (m + n), fonctionne de manière cyclique sur les j mots successifs de Y, effectuant des réductions modulo intermédiaires sur les produits intermédiaires formés. Un multiple de N sélectionné spécialement, N', est utilisé de sorte que seule une réduction unique du produit intermédiaire basée sur N' garantit que le produit intermédiaire P n'est jamais plus long que (m + n) bits à la fin de chaque cycle. N' représente un multiple entier de N, et la valeur N' est sélectionnée de sorte que les (m - 1) bits les plus significatifs égalent '1', et le bit le moins significatif égale '0'.
Patent WO-9907736-A3 (WO)
Title: Medicaments regulant les lipoproteines
Inventor: BIHAIN BERNARD
IPC: G01N33/50
Filed: 1998-08-06
Abstract: Procédés et compositions pharmaceutiques utiles pour moduler les niveaux de lipoprotéines in vivo. L'invention découle de la découverte que l'activité du récepteur stimulé par lipolyse (LSR) peut être inhibée ou amplifiée par des agents exogènes, notamment des polypeptides.
Patent WO-0166418-A3 (WO)
Title: Bouchon verseur pour recipients a liquides
Inventor: LEE JUNG MIN
IPC: B65D77/28
Filed: 2001-03-05
Abstract: L'invention porte sur un bouchon verseur pour récipients à liquides comportant un corps tubulaire placé sur le bouchon du récipient et s'étendant vers le haut sur une longueur donnée, un tube de fonctionnement traversant le corps et s'étendant dans le récipient sur une longueur donné, et un capuchon situé au sommet du corps. Le corps et le tube peuvent passer d'une première position où ils se dressent verticalement au-dessus de la surface de l'ouverture du récipient à une deuxième position où ils sont parallèles à la surface de l'ouverture du récipient. Le corps comporte une partie pliable en accordéon, et le tube comporte également une partie pliable en accordéon correspondant à celle du corps.
Patent WO-9851788-A3 (WO)
Title: Procede et construction pouvant inhiber une migration cellulaire
Inventor: QUAX PAULUS HUBERTUS ANDREAS
IPC: C12N15/09
Filed: 1998-05-11
Abstract: L'invention concerne une molécule d'acide nucléique recombinante qui comprend un vecteur convenant pour une transfection ou une transduction de cellules mammaliennes. Lesdits vecteurs contiennent une insertion d'acide nucléique qui code un polypeptide (ou une protéine) hybride pouvant être exprimé et comprend deux domaines ayant, l'un une fonction de fixation, et l'autre une fonction effectrice. Le domaine ayant une fonction de fixation peut comprendre un domaine de fixation d'un récepteur, et le domaine ayant une fonction effectrice peut avoir une activité enzymatique, en particulier une activité d'inhibition de protéase. Le vecteur peut être un vecteur viral (adénovirus ou rétrovirus) ou non viral convenant pour une transfection ou une transduction de cellules mammaliennes. L'insertion d'acide nucléique qui code un polypeptide (ou une protéine) hybride pouvant être exprimé peut être assujettie à un promoteur spécifique d'une cellule ou d'un tissu. On décrit en outre un processus destiné à prévenir une activité protéolytique locale, une dégradation matricielle extracellulaire, une migration cellulaire, une invasion cellulaire ou un remodelage tissulaire, l'opération consistant à transfecter ou transduire les cellules en cause ou des cellules dans leur environnement avec la molécule d'acide nucléique recombinante pour obtenir localement l'expression du polypeptide (ou de la protéine) hybride codé par ladite molécule. On décrit enfin un processus de production du polypeptide ou de la protéine hybride par transfection ou transduction de cellules mammaliennes avec la molécule d'acide nucléique recombinante pour obtenir l'expression du polypeptide (ou de la protéine) hybride ainsi produit, et éventuellement le récupérer.
Patent WO-0049115-A3 (WO)
Title: Procede permettant d'obtenir des antioxydants naturels a partir des plantes
Inventor: BAUMAN DAVORIN
IPC: A23L1/00
Filed: 2000-02-14
Abstract: L'invention concerne un procédé consistant à extraire le matériau de plante désintégré au moyen d'un solvant organique ou d'un mélange de solvants, à une température de 0 à 100 °C, puis à effectuer un refroidissement rapide, et à séparer les huiles essentielles; à traiter le résidu de plante extrait à l'eau ou à la vapeur d'eau; à faire évaporer le solvant ou le mélange de solvants; à isoler les constituants antioxydants, par saturation de la solution concentrée avec un gaz, et à étendre la solution extraite saturée et concentrée; à distiller le résidu à l'aide de vapeur d'eau; à refroidir la suspension de constituants antioxydants extraits, et à séparer la liqueur mère; à sécher l'extrait contenant les constituants antioxydants. Les produits obtenus sont de grande qualité, du fait de leur teneur élevée en constituants antioxydants. Le procédé technique appliqué est moins astreignant que tous les procédés décrits jusqu'ici.
Patent SK-2372000-A3 (SK)
Title: Trelliswork modular scaffolding system
Inventor: MERKEL GERALD
IPC: E04G7/30
Filed: 1998-08-18
Abstract: A scaffolding system includes tubular columns (3) and horizontal and/or diagonal crossbars (1,2). One or more scaffolding joints (4) are arranged on each tubular column (3) and placed above and at a distance from each other. Connecting elements (1,2) are engaged with the joints nots. The tubular columns includes wedge-shaped pockets for wedge shaped plug in elements forming joints (4) and connecting elements (1,2), the wedge-shaped plug in elements (5) are arranged on the ends of the crossbars and engage with the wedge pockets (6) of varying geometry. The horizontal connecting elements (1) are mounted via above-mentioned linkage of the wedge-shaped plug-in element (5) and the wedge pocket. The diagonal crossbars (2) are mounted by means of wedge heads (7) which are arranged on each side of a diagonal brace (2.1) and are slid over the wedge pocket (6) of the tubular column (3) via the receiving opening located in the small front face lies in a flat position.
Patent SK-2532001-A3 (SK)
Title: Unsaturated hydroximic acid derivatives as parp inhibitors
Inventor: LITERATI NAGY PETER
IPC: A61K31/15
Filed: 1999-09-02
Abstract: The object of the invention consists of novel unsaturated hydroximic acid derivatives, the process for their preparation and as active substance such as compounds containing pharmaceutical compositions. The novel compounds possess valuable pharmaceutical effects, so they can be used in the treatment of states connected with energy deficiency of the cell caused by PARP inhibition, in diabetes complications, in oxygen deficient status of the heart and brain, in neurodegenerative diseases, in the treatment of autoimmune and/or viral diseases. In formula (I).
Patent SK-3302003-A3 (SK)
Inventor: ZACOK MIKULAS
IPC: H05B3/00
Filed: 2003-03-19
Abstract: Premena elektrickej energie z elektrických zdrojov 3 x
x 230/400 V 50/60 Hz na premenu tepelnej energie difúziou
elektrickej energie tvorenú z polovodičových difúznych
usmerňovačov na vyhotovenie kladného L+ pólu
a záporného L- pólu na využitie elektrickej energie
Patent SK-5682001-A3 (SK)
Title: Shaping method for producing plastic parts and device for carrying out said method
Inventor: STEMKE LOTHAR
IPC: B29C45/02
Filed: 1999-10-27
Abstract: The invention relates to compression injection plastic molding using a repository space, for the temporary storage of the molding material melt to prevent structural faults and reduce workpiece costs. The molten molding material is first fed into the repository space, whose volume corresponds to the volume of the mold cavity. When the injection process starts, the bottom of the piston aligns with the edge of the repository space and with the wall of the mold cavity so that a small amount of molding material melt reaches the mold cavity directly. The piston then slides into the cylinder. The repository space, which continuously becomes larger, is filled with a melted material at almost no pressure. The melt is conveyed into the plastic core until tho supply of the melted molding material is ended. The piston is then retracted, and the mold cavity is thus completely filled with molding material.
Patent SK-6092001-A3 (SK)
Title: Composition consisting of influenza virus surface proteins and dispensing device
Inventor: GLUCK REINHARD
IPC: A61K39/21
Filed: 1999-11-08
Abstract: The present invention relates to an improved pharmaceutical substance in addition to an improved dispensing device that allows for more effective nasal administration of a substance.
Patent SU-712033-A3 (SU)
Inventor: EKHRENDT UILYAM ARTUR
IPC: C23F11/00
Filed: 1976-09-15
Granted: 1980-01-25
Abstract: 1522248 Silicate coated sponge iron MIDREX CORP 26 Aug 1976 [19 Sept 1975] 35591/76 Heading B2E Oxidation of sponge iron is inhibited by treatment with an alkali metal silicate, preferably as an aqueous solution, e.g. by immersion or spraying. The alkali metal is preferably Na but may be K or Li. The treated sponge iron may be dried under oxidising conditions, e.g. at 250 to 400‹F.
Patent SU-795456-A3 (SU)
Inventor: FOJER LASLO
IPC: C07C303/22
Filed: 1977-05-05
Granted: 1981-01-07
Abstract: Compounds of the formula:   <IMAGE>   or pharmaceutically acceptable salts thereof, wherein:
Patent SU-993822-A3 (SU)
Inventor: BARDZHOTTI ALBERTO
IPC: C07H15/24
Filed: 1980-08-29
Granted: 1983-01-30
Abstract: Anthracycline glycosides of the formula I   <IMAGE> I  wherein R is hydrogen or hydroxy, one of R1 and R2 is methyl and the other of R1 and R2 is hydroxy, and pharmaceutically acceptable acid addition salts thereof, which are useful in treating certain mammalian tumors, are prepared by condensing daunomycinone with certain novel sugars in an inert organic solvent and in the presence of a soluble silver salt and a dehydrating agent to form the corresponding protected glycosides from which the protecting groups are removed. This gives the compounds wherein R is hydrogen. The former are converted to the corresponding hydroxyl compounds by treatment with bromine and sodium formate.
Patent SU-1060112-A3 (SU)
Inventor: MATSUMOTO YUN-ITI
IPC: C07D471/04
Filed: 1980-09-26
Granted: 1983-12-07
Abstract: The present invention provides a 1,8-naphthyridine compound of the formula
     wherein
     R is hydrogen, methyl, ethyl or propyl, and a nontoxic pharmaceutically acceptable salt thereof,   -an antibacterial agent comprising said 1,8-naphtyridine compound   -and a process for prearing a 1,8-naphtyridine compound of the above formula which comprises   (A) reacting a compound oftheformula:
     with a compound of the formula
     or (B) decomposing a compound of the formula
      or (C) treating a compound of the formula
     with an acid or base, and/or reducrively cleaving it.