baber/WOPTO huggingface dataset:
Patent JP-2659136-B2 (JP)
IPC: A61K49/22
Filed: 1989-09-28
Granted: 1997-09-30
Abstract: The present invention relates to an improved transmembrane loading procedure for efficient loading of amphiphatic drugs into liposomes using the transmembrane gradient of ammonium and of pH. The resulting liposomes loaded with the drug are stable and safe. The procedure is equally applicable for sustained release of liposome-encapsulated drugs. The liposomes may be used in ultrasound imaging to release CO2.
Patent JP-2860487-B2 (JP)
IPC: B01F5/00
Filed: 1989-10-23
Granted: 1999-02-24
Abstract: The invention relates to a method and an arrangement for the continuous diluting of a concentrated solution. A main tank (1) for the concentrated solution and a partial tank (2) for diluting liquid are connected to one another by means of an overflow pipe (4), whose open end is on a level with the level of the concentrated solution in the main tank (1). Diluting liquid is fed continuously by the feed line (5) to the partial tank (2), a small quantity of diluting liquid at the same time being diverted and fed to the main tank (1). The quantity of diluting liquid which is fed to the concentrated solution is of the same magnitude as the quantity of concentrated solution which is fed at the same time to the diluting liquid via the overflow pipe (4).
Patent JP-2506650-B2 (JP)
IPC: G01S15/60
Filed: 1985-12-20
Granted: 1996-06-12
Abstract: A transmitter (22) emtis a signal at the frequency of an oscillator (32). A reference phase-locked loop (34) provides a corresponding reference velocity voltage (Vt). The reflected signal is received by a receiver (24) and processed by a second phase-locked loop (48) which provides a Doppler velocity votlage (Vr) which is corrected by subtracting (58) the reference voltage (Vt). In order to avoid spurious response by the second PLL (48) a drop-out detector (46) provides a drop-out signal (D/O) when the amplitude of the received signal (fr) is below a threshold (Vth). The drop-out signal causes a low-pass filter (52) in the second PLL (48) to hold its output unchanged for the duration of the drop-out. A digitally implemented embodiment is also disclosed.
Patent JP-2706013-B2 (JP)
IPC: H04M3/42
Filed: 1991-10-09
Granted: 1998-01-28
Abstract: This invention relates to a method and apparatus for signaling telecommunications customer requests to a switching system. The basic signaling arrangement consists of a series of function calls, including a function type specifier (e.g.05) and an optional parameter of the function (e.g. 1234). Function calls are separated by delimiters which are strings of characters, such as ** or *#, that are unique and not to be confused with function type specifiers or parameters. Strings of function calls can be stored in a switching system and can be called by a speed calling request (21 or 31 ). The function type include types wherein a customer supplies a parameter, such as a personal identification code in an otherwise prespecified string of function calls. <IMAGE>
Patent JP-4570713-B2 (JP)
IPC: F16F9/32
Filed: 1999-10-14
Granted: 2010-10-27
Abstract: A shock absorber for a toy building set, said shock absorber comprising a substantially rod-shaped element that has, at its one end, a collar and a guide that has a sleeve which displaceably encloses the rod-shaped element; and wherein the rod-shaped element and the guide each comprises means for mounting on another construction; and wherein a spring is arranged which is, with its one end, in abutment on the rod-shaped element and, with its other end, in abutment on the sleeve in such a manner that it uses its spring force to displace said sleeve towards the collar on the first mounting element. The guide comprises a substantially air-filled cylinder element which has a substantially cylindrical inner wall which is configured such that the collar on the rod-shaped element is in displaceable abutment on the inner wall of the cylinder element, whereby a pneumatic shock absorbing effect is obtained. <IMAGE>
Patent JP-3319556-B2 (JP)
IPC: G10L19/06
Filed: 1995-11-28
Granted: 2002-09-03
Abstract: PROBLEM TO BE SOLVED: To provide a formant emphasis method capable of reducing an indistinct feeling with less processing amounts. SOLUTION: In the formant emphasis method emphasizing a formant being a peak part of a spectrum of an input sound signal and attenuating the trough part, the processing emphasizing the formant of the input sound signal and attenuating the trough part is performed by a spectrum emphasis filter 1101, and a spectrum slope incorporated in the output signal of the spectrum emphasis filter 1101 is corrected by a first characteristic variable filter 1103 adaptively varying its characteristic according to the characteristic of the input sound signal and a first characteristic fixed filter 1104.
Patent JP-3129451-B2 (JP)
IPC: C25B3/23
Filed: 1990-12-26
Granted: 2001-01-29
Abstract: An element for use in an electrochemical cell has a first zone for introducing an oxygen-containing gas and a second zone separated from first zone by the element, which has a membrane with first and second surfaces, conducts oxygen ions therebetween, and has a catalyst exposed to at least the first zone. The element may be used to separate oxygen. <IMAGE>
Patent JP-2572273-B2 (JP)
IPC: B21J13/02
Filed: 1987-12-03
Granted: 1997-01-16
Abstract: A method, and apparatus, for removing a formed component (5) from a die (6) and reloading the die with a fresh billet (4) to form another component, wherein the fresh billet is forced into the die from below causing the die to be raised from a die block and engage a member (42) which separates the die into segments. When the die is thus separated, the component disengages from the segments permitting them to return to the die block with the fresh billet therein. The component is held on top of the die to be removed by a transfer mechanism.
Patent JP-3396225-B2 (JP)
IPC: H04M11/06
Filed: 1998-05-26
Granted: 2003-04-14
Abstract: A full-featured data access arrangement (DAA) for connecting a modem to a public switched telephone network (PSTN) includes a bridge current loop circuit, a line in use detection circuit, an off hook relay, a loop current sense circuit, and an extension/remote event detector circuit. The off hook relay is connected in series with the current loop circuit to enable the DAA to detect external off hook and on hook events when the modem is in an on hook state. The DAA is configured to detect the off hook and subsequent on hook status of an extension telephone at a location even though the modem and a handset sharing a line connector with the modem are both in an on hook state. The DAA is also capable of detecting an off hook state of an extension telephone even though the modem is in an off hook state. In addition, the DAA can detect when a remote telephone device that initiates an incoming call is placed on hook.
Patent JP-3515120-B2 (JP)
IPC: C08K3/36
Filed: 1995-07-06
Granted: 2004-04-05
Abstract: A polymeric film comprising from 0.0005% to 2% by weight, based upon the weight of the polymer in the film, of filler particles having a volume distributed median particle diameter of from 0.1 to 12.5  mu m, the filler particles being obtainable by calcining precursor silicone resin particles prior to incorporation into the film polymer.
Patent JP-3369563-B2 (JP)
IPC: B65D83/16
Filed: 1993-08-23
Granted: 2003-01-20
Abstract: Pushbutton-distributor characterized in that the upper part (4) of its body (1) is surrounded by a ring (2) which is free to rotate but which is wedged in axial translation, and radialy extended by a manual actuation lever (18), and in that the edge (21) of the ring on the side of the body base is diametrally inclined, the ring being shorter below the lever, while its longer side, diametrally opposite to the lever, is in the immediate vicinity of a circular shoulder (5) of the external wall of the base (3) of the body.
Patent JP-3614435-B2 (JP)
IPC: A61K31/00
Filed: 1995-08-14
Granted: 2005-01-26
Abstract: The present invention provides a method of treating anxiety and related disorders using an agonist which acts at negatively coupled cAMP-linked metabotropic glutamate receptors.
Patent JP-2825347-B2 (JP)
IPC: F16D48/04
Filed: 1991-05-08
Granted: 1998-11-18
Abstract: PCT No. PCT/NO91/00068 Sec. 371 Date Oct. 28, 1992 Sec. 102(e) Date Oct. 28, 1992 PCT Filed May 8, 1991 PCT Pub. No. WO91/17372 PCT Pub. Date Nov. 14, 1991.A clutch-servo for vehicles which constitutes a working device arranged for fluid connection with a master cylinder to be operated by the vehicle's driver. The servo comprises a working cylinder unit (50) with a piston (5) arranged in a working cylinder (1), which piston is connected to the clutch's engaging mechanism, and a control valve unit (60) for the working cylinder unit (50), with a valve body (21) arranged in the valve housing (44). The master cylinder has a fluid connection with the working cylinder unit (50) and the control valve unit (60), so that the fluid in the master cylinder simultaneously exerts a force on the piston (5) and the valve body (21), in order to try to release the clutch and to move the valve body (21) in order to connect the working cylinder unit (50) to a servo pressure fluid source when the driver operates the master cylinder. According to the invention the valve unit is constituted by a slide valve. Furthermore, the connection between the working cylinder unit (50) and the valve unit (60) is not dependent on mechanical function.
Patent JP-3567225-B2 (JP)
IPC: B22D11/119
Filed: 1996-08-16
Granted: 2004-09-22
Abstract: Thin metal strips, for example wide carbon steel strips, are cast in a single belt machine. The width of the molten metal on the belt is defined by side dams (12, 13) on the belt (11). The side dams have inwardly directed surfaces against the molten metal which makes the surface of the molten metal even also at its edges.
Patent JP-3202748-B2 (JP)
IPC: C07C51/573
Filed: 1992-04-02
Granted: 2001-08-27
Abstract: Unsaturated ketones such as mesityl oxide may be removed from acetic anhydride, or mixtures of acetic anhydride and acetic acid, by heating a solution comprising (1) acetic anhydride, or a mixture of acetic anhydride and acetic acid, (2) an  alpha , beta -unsaturated ketone, (3) ferrous (Fe II) and/or cobaltous (Co II) ion, (4) a cation selected from alkali metals, alkaline earth metals, quaternary organoammonium, quaternary organophosphonium and mixtures thereof, and (5) iodide ion.
Patent JP-3553948-B2 (JP)
IPC: C12N9/88
Filed: 1994-10-15
Granted: 2004-08-11
Abstract: PCT No. PCT/EP94/03399 Sec. 371 Date Jul. 2, 1996 Sec. 102(e) Date Jul. 2, 1996 PCT Filed Oct. 15, 1994 PCT Pub. No. WO95/10618 PCT Pub. Date Apr. 20, 1996A method of preparing  alpha -1,4-glucan lyase enzymes is described. The method comprises isolating the enzymes from a fungally infected algae. The amino acid sequences of the enzymes have been determined. The nucleic acid sequences coding for the enzymes have also been determined.
Patent JP-3648554-B2 (JP)
IPC: C07D263/04
Filed: 1993-11-18
Granted: 2005-05-18
Abstract: PCT No. PCT/FR93/01133 Sec. 371 Date May 19, 1995 Sec. 102(e) Date May 19, 1995 PCT Filed Nov. 18, 1993 PCT Pub. No. WO94/12482 PCT Pub. Date Jun. 9, 1994Method for the preparation of 1,3-oxazolidin 5-carboxylic acid having the general formula (I)   ormula (II)    <IMAGE>  (II)  In the general formulas (I) and (II), Ar is an aryl radical, R1 is a benzoyl radical or a radical R2-O-CO- wherein R2 is an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclyl radical, Ph is an optionally substituted phenyl radical, X is the residue of an optically active organic base or an alkoxy radical optionally substituted by a phenyl radical. The acids of formulas (I) and (II) are particularly useful in preparing taxol, Taxotere or analogs thereof which have remarkable antitumor and antileukemia properties.
Patent JP-4440342-B2 (JP)
IPC: C12N5/0783
Filed: 1995-11-16
Granted: 2010-03-24
Abstract: A method of producing a natural nonrecombinant cytokine mixture is disclosed including the steps of immobilizing at least one mitogen in a tissue culture vessel. An isolated population of lymphocytes free of neutrophils and erythrocytes, is suspended in a serum-free media and placed in the vessel. The lymphocytes are cultured, the media removed, and characterized for the yield of cytokines.
Patent JP-4283889-B2 (JP)
IPC: A61K39/395
Filed: 1994-12-22
Granted: 2009-06-24
Abstract: A non-toxic mucosal adjuvant is provided which may be admixed with further antigens to provide a vaccine administrable to mucosal surfaces in organisms including man. Preferably, the non-toxic mucosal adjuvant is a detoxified mutant of a bacterial ADP-ribosylating toxin, optionally comprising one or more amino acid additions, deletions or substitutions.
Patent JP-4134336-B2 (JP)
IPC: A63B41/08
Filed: 1997-10-15
Granted: 2008-08-20
Abstract: A football teaching aid comprises a football ( 20 ) having a number of differently coloured target areas ( 21, 22, 23, 24 ) marked on the surface of the football ( 20 ), each indicating an area on the surface of the football ( 2 ) to be struck to send the football ( 20 ) along an associated flight path. Thus, in practice, a football coach can direct a player to strike the football ( 2 ) in one of the coloured target areas ( 21, 22, 23, 24 ), which is easily identified by the player, to achieve a desired shot.
Patent JP-4041541-B2 (JP)
IPC: G01N33/577
Filed: 1997-10-20
Granted: 2008-01-30
Abstract: The invention concerns monoclonal antibodies against the epitope YPYDVPDYA (SEQ ID NO: 1) which is derived from the haemagglutinin of the human influenza virus and are suitable for the detection and isolation of native haemagglutinin of the human influenza virus, of modified haemagglutinin or of haemagglutinin fusion proteins and have an affinity of >10<SUP>8 </SUP>M<SUP>-1</SUP>, in particular of 10<SUP>9 </SUP>to 10<SUP>10 </SUP>M<SUP>-1</SUP>.
Patent JP-3976334-B2 (JP)
IPC: G01N33/569
Filed: 1994-03-21
Granted: 2007-09-19
Abstract: This invention relates to a new protein, designated Rib, and subfragments, multiples or variants thereof, which confers protective immunity against infection with many group B streptococcal strains, in particular those of serotype III. The invention includes a procedure for purification of the protein, a procedure for preparation of highly specific antibodies, a reagent kit, a DNA sequence encoding the protein and a pharmaceutical composition comprising the protein or fragments or variants thereof.
Patent JP-2823700-B2 (JP)
IPC: A61K31/04
Filed: 1995-02-23
Granted: 1998-11-11
Abstract: PCT No. PCT/EP95/00654 Sec. 371 Date Jul. 1, 1997 Sec. 102(e) Date Jul. 1, 1997 PCT Filed Feb. 22, 1995 PCT Pub. No. WO95/22964 PCT Pub. Date Aug. 31, 1995The pharmaceutical use of nitroglycerin, which is also designated as glycerol trinitrate or, chemically, as 1,2,3-propanetriol trinitrate, in a transdermal application form prevents undesired labour in pregnant mammals. The pharmaceutical use prevents premature labour.
Patent JP-3506706-B2 (JP)
IPC: H01B7/00
Filed: 1994-05-03
Granted: 2004-03-15
Abstract: A side entry heat recoverable article (2) pre-formed to enable a wire bundle (4) to be easily positioned and maintained within the article prior to recovery of the article. The wire bundle snaps into an enlarged section (6) between tab portions (10, 12). An adhesive (24) is disposed on the interior surface of the article for securing the tab portions together and for sealing the wire bundle. Upon recovery of the article, the wire bundle is thereby sealed within the heat recoverable article. A heat recoverable tube (2'), including adhesive, undergoes a post processing step to form the slit sleeve (2) that can be easily handled and installed.
Patent JP-3431635-B2 (JP)
IPC: C04B18/14
Filed: 1997-12-09
Granted: 2003-07-28
Abstract: The invention is directed at an additive for incorporation into a cementitious compound comprising Portland cement and water prior to the setting of the compound. The additive is comprised of a surface treated additive wherein the surfaces of the additive are treated with a substance which has a transient hydrophobic effect on the additive, which effect temporarily renders the additive more hydrophobic for a time period following the incorporation of the additive into the compound such that the water comprising the compound is less attracted to the additive during the placement of the compound and is thus available to provide workability to the compound, and such that the additive regains its natural properties following placement of the compound in order to permit the additive to participate with the compound during the curing of the compound. The invention is also directed at a process for preparing the additive and a process for preparing a cementitious compound comprised of the additive.
Patent JP-3050605-B2 (JP)
IPC: H05B44/00
Filed: 1996-03-12
Granted: 2000-06-12
Abstract: Light-emitting bipolar devices consist of a light-emitter formed from an electroluminescent organic light-emitting material in contact with an insulating material. The light emitter is in contact with two electrodes that are maintained in spaced apart relation with each other. The light emitter can be formed as an integral mixture of light emitting materials and insulating materials or as separate layers of light-emitting and insulating materials. The devices operate with AC voltage of less than twenty-four volts and in some instances at less than five volts. Under AC driving, the devices produce modulated light output that can be frequency or amplitude modulated. Under DC driving, the devices operate in both forward and reverse bias.
Patent JP-4090078-B2 (JP)
IPC: C07C33/22
Filed: 1998-03-20
Granted: 2008-05-28
Abstract: A catalytic transfer hydrogenation process is provided. The catalyst employed in the process is a metal cyclopentadienyl complex which is coordinated to defined bidentate ligands. Preferred metals include rhodium, ruthenium and iridium. Preferred bidentate ligands are diamines and aminoalcohols, particularly those comprising chiral centers. The hydrogen donor is advantageously a secondary alcohol or a mixture of triethylamine and formic acid. The process can be employed to transfer hydrogenate ketones and imines, which are preferably prochiral. Catalysts for use in such a process are also provided.
Patent JP-4699576-B2 (JP)
IPC: A61P1/04
Filed: 1998-05-15
Granted: 2011-06-15
Abstract: The invention relates to glucagon-related peptides and their use for the prevention or treatment of disorders involving the upper gastrointestinal tract including the esophagus and stomach. In particular, it has now been demonstrated that GLP-2 and peptidic agonists of GLP-2 can cause proliferation of the tissue of the upper gastrointestinal tract. Thus, the invention provides methods of proliferating the upper gastrointestinal tract in a subject in need thereof. Further, the methods of the invention are useful to treat or prevent inflammatory conditions of the upper gastrointestinal tract, including inflammatory diseases.  GLP-2 stimulates the growth of upper gastrointestinal tissue when administered in conjunction with other peptide hormones. The invention further provides pharmaceutical compositions of GLP-2 with at least one other peptide hormone, methods of enhancing the growth of upper gastrointestinal tissue and of gastrointestinal disorders by increasing serum levels of GLP-2 and at least one other peptide hormone, an kits for performing the methods of the invention.
Patent ES-2301419-B2 (ES)
Title: Proceso de lixiviacion para concentrados de cobre.
Inventor: DIXON DAVID G
IPC: C25C1/12
Filed: 2005-05-27
Granted: 2009-04-01
Abstract: Método para lixiviar cobre a partir de concentrados que contiene sulfitos, tales como calcopirita, que incluye utilizar pirita como catalizador para la reduccion férrica con objeto de eliminar la pasivación de la superficie de la calopirita, siendo llevado a cabo el proceso bajo condiciones en las cuales la pirita no está oxidada a un nivel adecuado. La lixiviacion se lleva a cabo en un medio de sulfato ácido y puede incluir oxidación por un gas que contiene oxígeno. El cobre lixiviado es recuperado entonces, por ejemplo, por extracción del solvente y extracción electrolítica. El proceso de lixiviación puede resultar en la extracción completa de cobre a presion atmosférica en tan solo cuatro horas.
Patent ES-2337537-B2 (ES)
Title: Preparado alimenticio y composicion farmaceutica que contiene un extracto embrionario y sus respectivos usos.
Inventor: CUNILL AIXELA JOAN
IPC: A23L15/00
Filed: 2008-03-19
Granted: 2011-02-02
Abstract: Preparado alimenticio y composición farmacéutica
que  contiene un extracto embrionario y sus respectivos usos.
El preparado alimenticio comprende un germen embrionario en fase
final de gástrula extraído de un huevo fecundado e incubado. Por
otro lado, la composición farmacéutica contiene corno sustancia
activa un extracto embrionario en la etapa de desarrollo embrionario
final de gástrula extraído de un huevo fecundado e incubado. Dicho
preparado se usa como complemento alimenticio para la prevención de
la caída de pelo. Por otro lado, dicha composición farmacéutica
puede ser utilizada corno medicamento para tratamientos
antidegenerativos.
Patent IE-S86971-B2 (IE)
Title: Compositions and methods for nourishing mammals
Inventor: ALAN ROSENBERG
IPC: A23K20/00
Filed: 2018-11-09
Abstract: The invention relates to oral isotonic compositions characterized by no residual chlorine taste for the hydration of mammals. In particular, this invention relates to oral compositions comprising at least three members of a group consisting of steviol glycoside, citric acid monohydrate, monosodium glutamate, glycine, mixtures and derivatives thereof; which may additionally comprise prebiotic derivatives and mixtures thereof. <Figure 1>
Patent AU-2001229219-B2 (AU)
Title: Valve regulated lead acid battery
Inventor: FLEMING FRANK ALBERT
IPC: H01M50/55
Filed: 2000-11-07
Granted: 2005-11-10
Abstract: A valve-regulated lead acid (VRLA) battery cell (2,40) has positive and negative plates (10,11,41,42) separated by separator media (12,43) and held together under pressure. The separator is adapted to support therein an electrolyte. Each plate has a first single or plurality of tabs (12,13,46) on a first side and a second single or plurality of tabs (15,16,47) on a second side of the plate, each tab being connected to a busbar (17,18,49,50) to form positive and negative busbars on each of the first and second sides of the plate. The cell may be alternatively configured in a spirally-wound arrangement or in a prismatic arrangement of flat plates. The cell may be constructed of a plurality of such positive and negative plates. A VLRA battery (1, 40) may be constructed of one or a plurality of such VLRA cells, in which case the busbars of neighboring cells are connected by welded joints. The busbars are serviced by at least plural pairs of positive and negative terminals (24,25,33,34,52,53,54,55).
Patent AU-2001283946-B2 (AU)
Title: A novel member of the EphA receptor family
Inventor: HOCK BJORN
IPC: C12P21/02
Filed: 2001-07-17
Granted: 2006-08-17
Abstract: EphA9 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing EphA9 polypeptides and polynucleotides in diagnostic assays.
Patent AU-2001294599-B2 (AU)
Title: Detection of rpoB sequences of Mycobacterium tuberculosis
Inventor: JUCKER MARKUS T
IPC: C12Q1/689
Filed: 2001-09-18
Granted: 2007-06-28
Abstract: A method of detecting <i>rpoB</i> sequences of <i>Mycobacterium tuberculosis</i> present in a biological sample that includes amplifying the <i>M. tuberculosis rpoB</i> sequence <i>in vitro</i> in a nucleic acid amplification mixture that includes specific primer sequences is disclosed. Compositions for detecting <i>in vitro</i> the <i>rpoB</i> sequences of <i>M. tuberculosis</i> in a sample are disclosed.