baber/WOPTO huggingface dataset:
Patent WO-2020082047-A1 (WO)
Title: Compositions and methods for treating alpha-1 antitrypsin deficiencey
Inventor: FINN JOHN
IPC: A61K48/00
Filed: 2019-10-18
Abstract: Compositions and methods for expressing alpha 1 antitrypsin (AAT) in a host cell are provided. Also provided are compositions and methods for treating subjects having alpha 1 antitrypsin deficiency (AATD).
Patent WO-2020086882-A1 (WO)
Inventor: LIU HUIPING
IPC: A61P35/00
Filed: 2019-10-24
Abstract: Disclosed are methods for treating cancer in a subject. The methods typically include administering to the subject a therapeutic agent that inhibits aggregation of tumor cells.
Patent WO-2020097286-A1 (WO)
Inventor: WEAVER RANDALL
IPC: E21B33/06
Filed: 2019-11-07
Abstract: A blowout preventer includes a housing including a longitudinal passage and a pair of ram passages extending from the longitudinal passage, a first ram assembly disposed in a first of the pair of ram passages and including first ram block assembly, and a second ram assembly disposed in a second of the pair of ram passages and including a second ram block assembly, wherein the first ram block assembly is configured to include a first configuration in which it sealingly engages an outer surface of a tubular member extending through the longitudinal passage of the housing when the blowout preventer is in a closed position, and a second configuration in which it sealingly engages the second ram block assembly when the blowout preventer is in the closed position.
Patent WO-2020142140-A1 (WO)
Inventor: DAS KUNAL
IPC: G01R33/035
Filed: 2019-11-12
Abstract: Embodiments relate to a sensor system configured to detect physical rotation, entire or relative, of one or more objects and/or their environment and/or proximity of a magnetic field, by measuring the degree of localization of a medium trapped in a ring-shaped artificial lattice. The lattice structure can be configured to comprise of lattice sites distributed with a lattice period around an azimuth of a closed ring. The site depths of the plurality of lattice sites can be configured to be modulated with a modulation period different from the lattice period to affect the onsite energies of each lattice site and the eigenstates of the system. Physical rotation of the sensor and/or the proximity of magnetic field will alter the localization properties so as to cause the degree of localization of the medium to change (e.g., the medium becomes more confined in space or more spread out in space).
Patent WO-2020162999-A1 (WO)
Inventor: RAGHAVAN VASANTHAN
IPC: H04B7/08
Filed: 2019-11-12
Abstract: L'invention concerne des procédés, des systèmes et des dispositifs destinés à des communications sans fil. Un premier dispositif sans fil peut recevoir un premier rapport de mesure de faisceau en provenance d'un second dispositif sans fil, le premier rapport de mesure de faisceau indiquant un premier ensemble de mesures de faisceau d'un canal sans fil entre le premier dispositif sans fil et le second dispositif sans fil. Le premier dispositif sans fil peut transmettre au second dispositif sans fil une mesure de validité de grappe d'au moins un faisceau dans le premier rapport de mesure de faisceau. Le premier dispositif sans fil peut recevoir du second dispositif sans fil, en réponse à la transmission de la mesure de validité de grappe, un second rapport de mesure de faisceau indiquant un second ensemble de mesures de faisceau du canal sans fil. Le premier dispositif sans fil peut sélectionner un faisceau de transmission au second dispositif sans fil sur la base, au moins en partie, des premier et second rapports de mesure de faisceau.
Patent WO-2020112622-A1 (WO)
Inventor: TYLER GREGORY
IPC: A61B5/0215
Filed: 2019-11-25
Abstract: Catheterization methods and apparatuses allow sensing of pressures inside the heart and for removing air from catheters. A delivery system can use the same components that are used to deliver a valve repair or replacement device to measure the pressure in the atrium or other heart chamber. A pressure sensor can be included in one of the catheters of the delivery system or pressure can be sensed through the same port that is used to flush a catheter. The delivery system can be inserted into an atrium of the heart, delivering the valve repair or replacement device to the native valve, such as the mitral valve, the tricuspid valve, the aortic valve, or the pulmonary valve.
Patent WO-2021107950-A1 (WO)
Inventor: RAMOS JOSE DIRCEU GRUNDLER
IPC: G06F12/02
Filed: 2019-11-27
Abstract: A call with respect to data for a file from an application program running on a computing device to a block-oriented file access function of an operating system running on the computing device is intercepted. A DAX file access is responsively performed with respect to a memory region of a persistent memory storing the file and an application buffer for the application program within an application memory space to which the memory region has been mapped.
Patent WO-2020123631-A1 (WO)
Title: Chambre à vapeur
Inventor: LEWIS RYAN JOHN
IPC: F28D15/02
Filed: 2019-12-11
Abstract: L'objectif de l'invention est de mettre au point une chambre à vapeur présentant une excellente fonction de mise en circulation d'un liquide de travail d'une partie d'extrémité à une partie centrale d'une mèche et permettant d'empêcher l'apparition d'un assèchement. À cet effet, la chambre à vapeur selon l'invention comprend : une enveloppe formée à partir d'une première feuille et d'une seconde feuille opposées l'une à l'autre et dont les périphéries extérieures sont liées l'une à l'autre ; un liquide actif isolé dans l'enveloppe ; et une mèche agencée au niveau d'une surface de paroi interne de la première feuille ou de la seconde feuille. Une partie de paroi est disposée autour de la mèche, vue de dessus de l'intérieur de l'enveloppe.
Patent WO-2021118575-A1 (WO)
Inventor: LLULL PATRICK
IPC: G09G5/397
Filed: 2019-12-12
Abstract: A display system (100) including a tracking subsystem (104) configured to track one of a pose of a head of a viewer or a pose of an eye of the viewer. The display system further includes an image correction module (310) configured to, for each pixel of at least a subset of pixels of an input image (318), determine a pixel view angle for the pixel based on the pose or the gaze direction, determine a corrected pixel value based on an input pixel value of the pixel in the input image and based on the pixel view angle; and provide the corrected pixel value for the pixel in an angle-corrected image (322) corresponding to the input image. The display system further includes a display panel (106) to display the angle-corrected image.
Patent WO-2021086421-A1 (WO)
Title: Using a supplementary uplink to mitigate a desensitization condition
Inventor: HE FEI
IPC: H04W72/12
Filed: 2019-12-19
Abstract: This disclosure describes systems and techniques directed to using a supplementary uplink (SUL) to mitigate a desensitization condition. The described systems and techniques include a user equipment (110) having a desensitization manager application (214) that directs the user equipment (110) to determine (606) a presence of a desensitization condition (410). The desensitization manager application (214) further directs the user equipment (110) to transmit (608), to a base station (120), a first message that requests the base station (120) to allocate, to the user equipment (110), a portion (418) of resources (416) used for a supplementary uplink between the user equipment (110) and the base station (120). After receiving (610) a second a message from the base station (120) that identifies the allocated portion (418) of the resources (416), the desensitization manager application (214) directs the user equipment (110) perform uplink transmissions (612) using the allocated portion (418) of the resources (416).
Patent WO-2021133412-A1 (WO)
Title: Gestion de faisceau et étalonnage d'antenne dans des systèmes mimo
Inventor: TALWAR SHILPA
IPC: H04B17/12
Filed: 2019-12-27
Abstract: Sont décrits ici une technologie à ondes millimétriques (mmWave) et à ondes submillimétriques (sub-mmWave), des appareils et des procédés se rapportant à des émetteurs-récepteurs et à des récepteurs, destinés aux communications sans fil. Les divers aspects comprennent un appareil d'un dispositif de communication comprenant un réseau d'antennes et un circuit de traitement couplé au réseau d'antennes. Le circuit de traitement est configuré pour initialiser un algorithme de suivi de faisceau sur la base de signaux reçus reçus au niveau du réseau d'antennes, les phases d'antenne utilisées dans le suivi de faisceau étant limitées par une limite de phase supérieure et une limite de phase inférieure, pour générer un résultat de suivi de faisceau. Le circuit de traitement est en outre configuré pour générer un vecteur d'étalonnage sur la base du résultat de suivi de faisceau et pour recevoir des transmissions ultérieures à l'aide d'un livre de codes adapté sur la base du vecteur d'étalonnage.
Patent WO-2020142460-A1 (WO)
Title: Robotic end effector with dorsally supported actuation mechanism
Inventor: SMITH FRASER M
IPC: B25J15/02
Filed: 2019-12-30
Abstract: A robotic end-effector to provide an anthropomorphic hand with a dorsal actuation system. The hand has a substantially planar palm and fingers extending from the palm and capable of flexion and extension relative to the palm. The dorsal actuation system is supported on the palm and fingers, with actuators positioned at a dorsal side of the palm and links positioned at a dorsal side of the fingers.
Patent WO-2021091582-A1 (WO)
Title: Neurosome/astrosome compositions and methods of use
Inventor: ZINGER ASSAF YOSEF
IPC: A61K9/50
Filed: 2020-11-09
Abstract: Disclosed are methods for the production and testing of formulated biomimetic nanoparticles. These particles can be utilized towards promoting neural health and connectivity, for example, after injury and in diseased states.
Patent WO-2020150555-A1 (WO)
Inventor: RAGLIN JOHN
IPC: E21B43/12
Filed: 2020-01-17
Abstract: A separator for separating gas from a fluid mixture in a production stream of a well. The separator includes an outer tube and an inner tube positioned concentrically with the outer tube. The production stream is directed through the outer tube and into a space between a well casing of the well and the outer tube where gas in the production stream can separate from fluid in the production stream. The separated fluid is then directed through the inner tube to a pump.
Patent WO-2020150738-A1 (WO)
Title: Procédés de modulation de la réponse aux corticostéroïdes
Inventor: WRIGHT DALE
IPC: C07K7/06
Filed: 2020-01-21
Abstract: La présente invention concerne des procédés de modulation de réponses aux corticostéroïdes chez des sujets en ayant besoin.
Patent WO-2020219130-A1 (WO)
Inventor: HU WENJING
IPC: A61F13/00
Filed: 2020-01-22
Abstract: A system for analyzing a wound fluid. The system includes a transparent layer, a membrane layer, and an indicator layer that contains a colorimetric or fluorescent indicator reagent for detecting pH, a nitrite, an enzyme, a reactive oxygen species, a reactive nitrogen species, a nucleic acid, or a combination thereof. The membrane layer is impermeable to blood clots and cellular debris and is permeable to wound fluid. Also provided are methods for analyzing a wound fluid and for detecting biological fluid on biomedical instruments and waste materials using the system.
Patent WO-2020167449-A1 (WO)
Title: Procédés et dispositifs de modulation d'ondes delta
Inventor: MIKSA WESLEY
IPC: A61B5/00
Filed: 2020-01-24
Abstract: L'invention concerne des procédés et des dispositifs pour moduler des ondes cérébrales delta chez un sujet endormi. Dans divers modes de réalisation, le procédé consistant à : a) détecter et surveiller une onde delta initiale chez un sujet, b) appliquer un courant électrique pour moduler l'onde delta initiale chez le sujet, ce qui permet de modifier l'onde delta initiale chez le sujet pour former une onde delta modifiée, et, c) éventuellement, répéter les cycles les étapes a) et b), ce qui permet de moduler les ondes cérébrales delta.
Patent WO-2020159955-A1 (WO)
Inventor: MOLONEY JEREMY
IPC: C09K8/54
Filed: 2020-01-28
Abstract: L'invention concerne les procédés d'utilisation d'un polyglycoside d'alkyle cationique dans une composition de lutte contre la corrosion pour réduire la corrosion des surfaces métalliques dans un réseau d'alimentation en eau. Les procédés ou compositions de l'invention s'avèrent plus efficaces que les procédés ou compositions comprenant des inhibiteurs de corrosion couramment utilisés pour des réseaux d'alimentation en eau.
Patent WO-2020160293-A1 (WO)
Inventor: DAGUM PAUL
IPC: G16H50/70
Filed: 2020-01-30
Abstract: La présente invention concerne des procédés, des systèmes et des produits de programme informatique pour prévoir des changements d'humeur à partir de biomarqueurs numériques et, plus généralement, pour prédire des changements dans une évaluation clinique neuropsychologique. Des données d'interaction d'utilisateur indicatives d'une interaction d'un utilisateur avec un dispositif mobile sont capturées passivement sur une période de temps et peuvent comprendre des temporisations de clavier. Une mise en correspondance de fonction est exécutée pour calculer un biomarqueur numérique pour une grandeur de santé cérébrale à partir des données d'interaction d'utilisateur capturées. Un biomarqueur numérique antérieur pour la grandeur de santé cérébrale (calculée à partir de données d'interaction d'utilisateur capturées précédemment par exécution de la mise en correspondance de fonction) est extrait. Une différence est détectée entre le biomarqueur numérique et le biomarqueur numérique antérieur. Un changement d'un score du score de test neuropsychologique est prévu pour se produire dans une plage de temps spécifiée dans le futur sur la base des différences détectées. Le changement prévu est délivré en sortie.
Patent WO-2020160543-A1 (WO)
Inventor: XIONG GANG
IPC: H04L5/02
Filed: 2020-02-03
Abstract: L'invention concerne une approche décrite pour une communication sans fil destinée à un système de cinquième génération (5G) ou nouvelle radio (NR). La communication sans fil comprend un gNode (gNB) configuré pour indiquer une attribution de ressources de domaine temporel dans une dimension de transformée de Fourier discrète (DFT) dans des informations de commande de liaison descendante (DCI) ; et pour transmettre un canal partagé de liaison descendante physique (PDSCH) à l'aide d'une forme d'onde de multiplexage par répartition orthogonale de la fréquence à transformée de Fourier discrète (DFT-s-OFDM) selon l'attribution de ressources dans le domaine temporel dans la dimension de DFT.
Patent WO-2020219148-A1 (WO)
Inventor: GUO PINGJUN
IPC: G01N33/24
Filed: 2020-02-18
Abstract: Systems and methods relating to determination of oil saturation, kerogen content, and/or water saturation within kerogen-containing subsurface formations such as unconventional formations (e.g., tight formations such as shales) are provided herein. These methods advantageously rely on a simplified measurement process, reducing the direct measurements of a subsurface formation relied upon in determining oil saturation, kerogen content, and/or water saturation. In particular, methods according to some embodiments include determining or otherwise obtaining values of TOC; bulk density; porosity; and densities of kerogen, oil, and water corresponding to a subsurface formation of interest or a zone thereof. Methods of various embodiments further include, based at least in part upon the obtained values, determining one or more of kerogen content, oil saturation So, and water saturation Sw of the subsurface formation of interest, and/or a corresponding zone thereof.
Patent WO-2020181203-A1 (WO)
Title: Method and apparatus for ephemeral roles implementing module
Inventor: ASHER ADRIAN
IPC: G06F15/18
Filed: 2020-03-06
Abstract: Various methods, apparatuses, and media for implementing a machine-learning model execution module are provided. A processor is configured to generate a machine-learning model. The machine learning model includes data related to a requester's access to one or more ephemeral roles. The processor receives a request from the requester to access the one or more ephemeral roles within the machine-learning model. The processor also determines the requester's group or role membership status within an organization. The processor also dynamically evaluates the received request with the machine learning model in real time to grant or deny access to the one or more ephemeral roles based on the membership status of the requester.
Patent WO-2020190764-A1 (WO)
Inventor: OJALA PASI SAKARI
IPC: H04W24/02
Filed: 2020-03-13
Abstract: Systems and methods are described for dynamic sensor network organization. In some embodiments, a first sensor node collects a data set and applies a selected analysis tool to generate a summary of the data set. The first sensor node also requests summary data from a second sensor node and identifies to the second sensor node the selected analysis tool to be used to generate that summary. The first sensor node receives the requested summary data and compares its own summary with the received summary. If the data summaries are sufficiently similar, the second sensor node may be considered redundant and may be instructed to enter a sleep mode. If the data summaries are sufficiently different, the second sensor node may be instructed to provide its collected data to the first sensor node. The analysis tool used to generate summaries may be selected from a plurality of available analysis tools.
Patent WO-2020186216-A1 (WO)
Title: Méthodes de traitement des acidémies organiques
Inventor: WAMHOFF BRIAN
IPC: A61K31/19
Filed: 2020-03-13
Abstract: La présente invention concerne des méthodes de traitement des acidémies organiques. Selon certains modes de réalisation, les méthodes consistent à réduire la production de propionyl-CoA, d'isovaléryl-CoA et de méthylmalonyl-CoA, et de divers métabolites apparentés, chez un sujet qui en a besoin.
Patent WO-2020191308-A1 (WO)
Inventor: LEMAY PAUL ROLAND
IPC: G06V30/40
Filed: 2020-03-20
Abstract: A medical device monitoring system and method extract information from screen images from medical device controllers, with a single OCR process invocation per screen image, despite critical information appearing in different screen locations, depending on which medical device controller's screen image is processed. For example, different software versions of the medical device controllers might display the same type of information in different screen locations. Copies of the critical screen information, one copy from each different screen location, are made in a mosaic image, and then the mosaic image is OCR processed to produce text results. Text is selectively extracted from the OCR text results, depending on contents of a selector field on the screen image, such as a software version number or a heart pump model identifier.
Patent WO-2021118622-A1 (WO)
Inventor: HINOUE TATSUYA
IPC: H01L27/1157
Filed: 2020-03-26
Abstract: A three-dimensional memory device includes alternating stacks of insulating layers and electrically conductive layers located over a substrate. Each of the alternating stacks laterally extend along a first horizontal direction, and neighboring pairs of the alternating stacks are laterally spaced apart along a horizontal direction by laterally alternating sequences of memory openings and dielectric pillar structures. Each of the memory openings contains a respective memory opening fill structure that includes a dielectric core, a first vertical semiconductor channel, a second vertical semiconductor channel, a first memory film, and a second memory film. The dielectric core contacts a pair of dielectric pillar structures among the dielectric pillar structures of the laterally alternating sequences.
Patent WO-2020210719-A1 (WO)
Inventor: DIACONU IULIA
IPC: A61K39/00
Filed: 2020-04-10
Abstract: Some embodiments of the disclosure provides a chimeric antigen receptor (CAR) comprising an antigen binding domain specific for FLT3, an antigen binding domain specific for a second antigen, a transmembrane domain, and an intracellular T cell signaling domain. Some embodiments of the disclosure provides bicistronic CARs. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of a proliferative disorder, e.g., cancer, in a mammal and methods of treating or preventing a proliferative disorder, e.g., cancer, in a mammal are also disclosed.
Patent WO-2020226882-A1 (WO)
Inventor: LI JARED
IPC: A61H1/02
Filed: 2020-04-17
Abstract: An exemplary embodiment of the present invention provides an exosuit support system, comprising first and second orthotic interfaces, first and second members, and first and second actuators. The first and second orthotic interfaces can be configured to attach to left and right legs of a user, respectively. The first member can comprise a first end connected to the first orthotic interface and a second end connected to a portion of the system configured to be positioned proximate a right shoulder of the user. The second member can comprise a first end connected to the second orthotic interface and a second end connected to a portion of the system configured to be positioned proximate a left shoulder of the user. The first actuator can be configured to apply a first tension to the first member. The second actuator can be configured to apply a second tension to the second member.
Patent WO-2021154319-A1 (WO)
Title: Editor for generating computational graphs
Inventor: SCHECHTER IAN
IPC: G06F8/41
Filed: 2020-04-30
Abstract: Techniques for generating a dataflow graph include generating a first dataflow graph with a plurality of first nodes representing first computer operations in processing data, with at least one of the first computer operations being a declarative operation that specifies one or more characteristics of one or more results of processing of data, and transforming the first dataflow graph into a second dataflow graph for processing data in accordance with the first computer operations, the second dataflow graph including a plurality of second nodes representing second computer operations, with at least one of the second nodes representing one or more imperative operations that implement the logic specified by the declarative operation, where the one or more imperative operations are unrepresented by the first nodes in the first dataflow graph.
Patent WO-2020232403-A1 (WO)
Title: Treatment of fibrosis with ire1 small molecule inhibitors
Inventor: VACCA JOSEPH P
IPC: C07D403/04
Filed: 2020-05-15
Abstract: Provided herein are methods of using IRE1 small molecule inhibitors in combination therapies for treating fibrosis in a subject. The IRE1 small molecule inhibitors described herein may be used in combination therapies for treating fibrosis
Patent WO-2021025750-A1 (WO)
Inventor: LIU DAVID
IPC: C12N9/22
Filed: 2020-05-20
Abstract: The present disclosure provides improved adenosine base editors (ABE) that have an expanded range of PAM sequence recognition capability ( i.e ., recognition of non-canonical 5̕ -NGG-3̕ PAM sequence). In addition, the present disclosure provides improved cytidine base editors (CBE) and adenosine base editors (ABE) comprising circular permutant variants of Cas9 (CP-Cas9) with an increased window of base editing within the protospacer sequence ( e.g ., from about 4-5 nucleotides to up to about 8-9 nucleotides) and even outside of the protospacer sequence.