baber/WOPTO huggingface dataset:
Patent CZ-304442-B6 (CZ)
Title: Oxycodone sustained release oral dosage form and pharmaceutical composition for treating pain
Inventor: OSHLACK BENJAMIN
IPC: A61K9/52
Filed: 2002-05-02
Abstract: In the present invention, there is disclosed a sustained release oral dosage form for once-a-day administration comprising: (a) a bilayer core comprising: (i) a drug layer comprising an analgesically effective amount of oxycodone or a pharmaceutically acceptable salt thereof; and (ii) a displacement layer comprising an osmopolymer; and (b) a semipermeable wall surrounding the bilayer core having a passageway disposed therein for the release of said oxycodone or pharmaceutically acceptable salt thereof wherein oxycodone or pharmaceutically acceptable salt thereof is the only substance in said dosage form. The dosage form of the present invention is adapted for providing an in-vitro release rate, of oxycodone or a pharmaceutically acceptable salt thereof, when measured by the USP Basket Method at 100 rpm in 900 ml aqueous buffer at a pH of between 1.6 and 7.2 at 37 C of from 0 to about 40 percent at 1 hour, from about 8 to about 70 percent at 4 hours, from about 20 to about 80 percent at 8 hours, from about 30 to about 95 percent at 12 hours, from about 35 to about 95 percent at 18 hrs, and greater than about 50 percent at 24 hours. Said dosage form providing an analgesic effect at least about 24 hours after oral administration at steady state to human patients and a mean Ci24/Cimax oxycodone ratio of 0.6 to 1.0 after oral administration at steady state to said patients. There is also disclosed the use of the above-described dosage form for the preparation of a pharmaceutical composition intended for the treatment of pain.
Patent SK-287996-B6 (SK)
Title: Pyrimide compound, pharmaceutical composition the compound is comprised, method for preparation thereof, combination and product containing the composition and use of the pyrimide compound
Inventor: ANDRIES KOENRAAD JOZEF LODEWIJK MARCEL
IPC: A61K31/506
Filed: 1999-03-24
Abstract: It is described use of the pyrimidine compounds for preparation the medicament intended for the treatment of HIV and pyrimidine compound of the general formula (I), which having HIV replication inhibiting properties, the process for preparing said compound and said pharmaceutical composition as well as a combination and product containing.
Patent SK-285310-B6 (SK)
Title: Rolling bearing
Inventor: FECKO TIBOR
IPC: F16C19/00
Filed: 1999-05-25
Abstract: Roller bearing having an inner ring (10), an outer ring (30), a set of rollers (12) which run between the inner ring (10) and outer ring (30) and having a cage (100) provided with two cage rings (101, 102), between which the rollers (12), are disposed on webs (104), which maintain a spacing by which the inner ring (10, 10.1, 10.2, 10.3) and/or the outer ring (30, 30.1, 30.2, 30.3) have respectively at least one annular flange (10b, 10c, 10b.1, 30''.1, 30'.2, 30''.2, 30'.3, 10c.3) for the rollers, whereby the webs (104, 104.1, 104.2, 104.3) taper in a radial direction and the inner ring (10, 10.1, 10.2, 10.3) and/or the outer ring (30, 30.1, 30.2, 30.3) has at least one axially open recess (30', 30'1, 10'2, 10'3) for one of the cage rings(101, 102; 101.1, 102.1; 101.2, 102.2; 101.3, 102.3).
Patent SK-288554-B6 (SK)
Title: Test equipment for evaluating surface properties of coatings and construction materials
Inventor: BRONCEK JOZEF
IPC: G01N19/02
Filed: 2014-09-05
Abstract: The test device for assessing the corrosion properties of surfaces and coatings of construction materials is designed to investigate the impact of mechanical and chemical effects on the surface degradation of material samples at contact load and friction in corrosive environments. Its essence is the optimal spatial arrangement of suitable mechanical and electrical elements that create a controlled and measurable corrosion node with a precisely defined rectilinear reciprocating movement of the friction members, generate a defined normal force in contact with the friction members, provide frictional force measurement in both directions, and measure the electrical potential generated by friction in a corrosive active environment. The device consists of a drive part providing a synchronous movement with a sinusoidal velocity which consists in particular of a driving motor (2) with a crank (3) and a pulley (4), which generate a precisely defined movement from the screen (5), furthermore from the measuring part, in particular a friction member (11) and a sample (13) immersed in a corrosive active liquid container (14). Normal force is generated by the weight (12), friction forces are measured by the force transducer (18) and the change in electrical potential is measured by the adjustable electrodes (19, 20).
Patent BR-PI9706586-B8 (BR)
Title: composição de tintura de oxidação para fibras queratínicas, processo de tintura das fibras queratínicas, dispositivo com vários compartimentos e uso de uma composição de tintura de oxidação
Inventor: Boudy Françoise
IPC: A61K8/41
Filed: 1997-07-10
Abstract: <b>"composição de tintura de oxidação para fibras queratínicas, processo de tintura das fibras queratínicas, dispositivo com vários compartimentos e utilização de uma composição de tintura de oxidação".<d> a presente invenção se refere a uma composição de tintura, particularmente para fibras queratínicas humanas, como os cabelos, que compreende, em um meio apropriado para a tintura, pelo menos um precursor de corante de oxidação e eventualmente um ou mais acopladores, e que se caracteriza pelo fato de compreender também um polímero anfifílico não-iônico que compreende pelo menos uma cadeia graxa e pelo menos um motivo hidrófilo. a presente invenção se refere também aos processos e dispositivos de tintura que utilizam esta composição de oxidação.
Patent EP-1427657-B8 (EP)
Inventor: DIETRICH FREDERIC SENIOR
IPC: B65G53/60
Filed: 2002-09-06
Granted: 2006-09-06
Abstract: A device for transferring a dusty, powdery, grain-like or granular conveyed material out of a storage receptacle and into a working or transfer receptacle or a similar accommodating space. The device comprises a working chamber, which is connected to a supply line for the conveyed material, and comprises a discharge cross-section. At least one feed line for a flow medium leads into the working chamber, and a filter device is located between the flow medium and the conveyed material. The supply line for the conveyed material leads into a tubular filter space, and a filter insert, which is also tubular and delimits said filter space, is placed inside the working chamber connected to an air line and/or to a gas line.
Patent EP-1730454-B8 (EP)
Inventor: MULLER CHRISTIAN
IPC: F25B21/00
Filed: 2005-03-29
Granted: 2007-11-21
Abstract: A heat generator comprising a magneto-caloric material and a method for generating efficient and reliable thermies enabling of substantially limiting displaceable inert masses in order to produce a magnetic field variation required for obtaining a magneto caloric effect and usable by individuals and/or industries. The generator (10) comprises magneto caloric thermal elements (Ti) which are circularly arranged and crossed by conduits containing coolant flowing therethrough and magnetic elements (Gi) exposing the thermal elements (Ti) to a magnetic field action. The generator (10) also comprises magnetic divergence (mj) elements arranged between the thermal elements (Ti) and the magnetic elements (Gi) and coupled to displacement mechanism (not represented) for moving from one thermal element (Ti) to another thermal element (Ti+1) and initiating the magnetic flux variation in the thermal elements (Ti), thereby promoting the calorie and/or frigorie generation. The generator (10) can be used for tempering, cooling, heating, conserving, drying and air-conditioning.
Patent EP-1711704-B8 (EP)
Inventor: HOFMEISTER CARL-EIKE
IPC: F02D41/38
Filed: 2006-01-20
Granted: 2008-04-23
Abstract: The invention relates to a method for monitoring an operability of an injection system of an internal combustion engine, during which in the event of a change in the injected amount of fuel, a cause of fault is detected based on the behavior of the pressure prevailing inside the high-pressure accumulator. According to the identified cause of the fault, a corresponding emergency control program is executed by the controller. The inventive method enables a simple and precise analysis of a cause of fault.
Patent EP-0783642-B8 (EP)
Inventor: GYLOV HANS HENRIK
IPC: G05D23/12
Filed: 1995-09-19
Granted: 2005-09-14
Abstract: Heat exchanger valve (8) with thermostat valve (12), a housing (9) with inlet (20) and outlet (21), a thermostat bellows displaceable spindle (30) with seal (42) which, by the expansion/contraction of the thermostat bellows and against the pressure of a surrounding spring (31), can close/open an opening (27) with a seating (27a) in a transverse wall (24) between the inlet (20) and the outlet (21), and a piston (13) controlled by differential pressure for the control of a medium's differential pressure across a pre-setting (11) and a thermostat valve (12) consisting of the seating (27a) and the seal (42) between the inlet (20) and the piston (13), the thermostat valve (12) being able to cut off the flow between the inlet and the outlet independently of the pre-setting (11). With the valve (8), only a predetermined maximum amount of the heat-carrying medium flows through the heat exchangers (5). If the differential pressure is increased when the valves on a pipe length are closed, the flow in the individual heat exchangers (5) is not increased.
Patent BR-PI0001268-B8 (BR)
Title: método e sistema para reconhecimento de voz
Inventor: DAVID ERICK CHEVALIER
IPC: G10L15/20
Filed: 2000-02-17
Abstract: <b>método e sistema de reconhecimento de voz<d> um sistema de reconhecimento de voz (204, 206, 207, 208) gera uma severidade de rejeição variável como uma função de pelo menos um nível de ruído de fundo medido durante o treinamento e medições de sinal de ruído feitas durante uma expressão vocal de entrada feita durante o modo de operação de reconhecimento. uma penalidade de entrada de palavra é atribuída como uma função da severidade de rejeição variável.
Patent BR-PI0208183-B8 (BR)
Title: peptídeo antígeno de câncer modificado por wt1 e vacinas para câncer
Inventor: HARUO SUGIYAMA
IPC: A61P35/00
Filed: 2002-03-22
Abstract: "peptídeo modificado por wt1". a presente invenção refere-se a um peptídeo de antígeno de câncer compreendendo a seqüência de aminoácido seguinte: cys tyr thr trp asn gln met asn leu (n<0> de id de seqüência 3), uma vacina para câncer tendo isto como seu ingrediente ativo, e uma vacina de dna tendo como seu ingrediente ativo dna que codifica este peptídeo.
Patent BR-PI0620566-B8 (BR)
Title: composição, composição para o tratamento profilático ou terapêutico de fibrose miocardial ou uma condição associada, composição para o tratamento profilático ou terapêutico de hipertensão, uso de uma composição, uso de vip ou de um fragmento do mesmo e uso de um vip
Inventor: KAREN ANNETTE DUGGAN
IPC: A61K38/04
Filed: 2006-12-08
Abstract: composição, composição para o tratamento profilático ou terapêutico de fibrose miocardial ou uma condição associada, composição para o tratamento profilático ou terapêutico de hipertensão, uso de uma composição, uso de vip ou de um fragmento do mesmo e uso de um vip. a invençâo relaciona-se com composições compreendendo uma quantidade farmaceuticamente efetiva de um ou mais fragmentos funcionais de peptídeo intestinal vasoativo (vip), e o uso daquelas composições no tratamento de fibrose, hipertensão e outras distúrbios.
Patent BR-PI0719361-B8 (BR)
Title: composto, composição farmacêutica, e, uso do composto
Inventor: ANTHONY J ROECKER
IPC: C07D491/052
Filed: 2007-11-30
Abstract: composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e uso de um composto ou de um sal farmaceuticamente aceitável do mesmo a presente invenção é dirigida a compostos de diazepan substituídos, que são antagonistas de receptores de orexina, e que são úteis no tratamento ou na prevenção de distúrbios neurológicos e psiquiátricos e em doenças, nas quais os receptores de orexina estão envolvidos. a invenção é também dirigida a composições farmacêuticas, que compreendem estes compostos e ao uso destes compostos e composições na prevenção ou no tratamento de tais doenças, nas quais os receptores de orexina estão envolvidos.
Patent BR-PI0721365-B8 (BR)
Title: método para secagem de um material biologicamente ativo
Inventor: GUOPENG ZHANG
IPC: C07K17/04
Filed: 2007-02-01
Abstract: método para secagem de um material biologicamente ativo. a presente invenção refere-se a um método para produzir espumas contendo materiais biológicos. uma pasta sólida ou semissólida é formada combinando o material biologicamente ativo com um agente protetor em um solvente aquoso. a pasta formada é permitida solidificar e pode ser então opcionalmente dividida na forma desejada. a pasta pode ser congelada para permitir a formação de cristais de gelo para agir como "porogens". subsequentemente, a pasta é exposta à energia radiante da onda em propagação sob vácuo (t-rev) para secagem. isso faz com que o solvente evapore, deixando o material seco contendo o material biologicamente ativo, o agente protetor e um conteúdo de água relativamente pequeno. materiais biologicamente ativos que podem ser usados incluem células, culturas microbianas, micróbios atenuados vivos, probióticos, leveduras, enzimas, vacinas, proteínas e qualquer material biológico sensível ao calor. pelo direcionamento da energia via uma onda em propagação através de uma amostra, um bom controle da temperatura e condições de processo pode ser realizado. o método proporciona uma alternativa para os métodos convencionais de lixiviação de particulado ou secagem por congelamento.
Patent BR-PI1006141-B8 (BR)
Title: composições de anticorpo modificado, métodos para preparar e usar as mesmas
Inventor: FRED GLUCK
IPC: A61K39/395
Filed: 2010-01-12
Abstract: anticorpo ativável , métodos para sua preparação e usos. a presente divulgação provê anticorpos modificados que contêm um anticorpo ou fragmento de anticorpo (ab) modificado com uma porção de mascaramento (mm). tais anticorpos modificados podem ser adicionalmente acoplados a uma porção clivável (cm), resultando em anticorpos ativáveis (aas), em que a cm é capaz de ser clivada, reduzida, fotolisada, ou modificada. aas podem apresentar uma conformação ativável tal que o ab esteja mais acessível a um alvo após, por exemplo, a remoção da m por clivagem, redução, ou fotólise da cm na presença de um agente capaz de clivar, reduzir ou fotolisar a cm. a divulgação provê ainda métodos para preparar e usar tais anticorpos modificados e anticorpos ativáveis.
Patent BR-PI1008855-B8 (BR)
Title: derivados de indol, seu uso como agentes anticâncer, seu processo para preparação e composição farmacêutica que os compreende
Inventor: BRUNO SCHOENTJES
IPC: A61K31/435
Filed: 2010-02-03
Abstract: derivados de indol como agentes anticâncer a presente invenção refere-se a compostos de fórmula (i), seu uso para o tratamento de câncer bem como composições farmacêuticas compreendendo os ditos compostos de fórmula (i).
Patent BR-112014018138-B8 (BR)
Title: composição de tratamento de superfície, meio de impressão e método para preparar uma composição de tratamento de superfície utilizada na fabricação de papel
Inventor: XIAOQI ZHOU
IPC: B41F23/00
Filed: 2012-01-31
Abstract: composição de tratamento de superfície, meio de impressão e método para preparar uma composição de tratamento de superfície utilizada na fabricação de papel uma composição de tratamento de superfície inclui uma solução tendo um ph dentro de uma faixa acima de 4 a 8, que inclui cátions metálicos produzidos in situ a partir de uma substância contendo metal tendo um ksp não maior que 1x10-6 em uma reação com um ácido tendo um pka em uma faixa de -3,0 a +3,5. a composição inclui ainda um agente misturado com a solução que é tanto um agente de dimensionamento de superfície quanto uma gente de revestimento utilizado sobre um substrato de papel. um meio de impressão inclui a composição aplicada a um substrato de papel. a preparação da composição inclui a reação da substância contendo metal com um ácido, ajuste de ph para acima de 4 a 8, e mistura de solução contendo cátion metálico tanto com o agente de dimensionamento de superfície ou agente de revestimento.
Patent AU-2015385869-B9 (AU)
Title: Method for preparing an optical element which colors in a non-uniform linear pattern
Inventor: TURPEN JOSEPH D
IPC: G02B5/23
Filed: 2015-03-10
Granted: 2020-09-03
Abstract: A method for preparing an optical element which colors in a non-uniform linear pattern is provided. The method includes (I) providing an optical element which previously has been treated with a photochromic composition containing at least one first photochromic material, the photochromic composition having an absorbance spectrum in the region of photochromic activation; (II) preparing at least one light-absorbing composition containing ultraviolet light absorber, a second photochromic material which is the same or different than the first photochromic material, or mixtures thereof, where the light-absorbing composition has an absorbance spectrum overlapping with that of the photochromic composition in the region of photochromic activation; (III) depositing the light-absorbing composition over the surface of the photochromic optical element in a controlled, predetermined pattern using an inkjet printing apparatus to provide a linearly gradient color pattern upon exposure to actinic radiation; (IV) and drying the composition. An optical element also is provided.
Patent DE-3308442-C1 (DE)
Title: Motor vehicle headlight
Inventor: BRUEGGER THEODOR
IPC: B60Q1/068
Filed: 1983-03-10
Granted: 1984-10-18
Abstract: The invention relates to a motor vehicle headlight whose adjustment screw is rotatably mounted in a fixed wall of the headlight. A washer is fixed on the threaded shaft by means of deformation, with the interposition of an elastic bushing which is prestressed in the direction of the axis of the screw. In the region of the washer which is to be clamped tight, the turns of the thread of the adjustment screw have at least one interruption into which material is forced when the washer is squeezed.
Patent DE-3439880-C1 (DE)
Inventor: SCHMIDT HELMUT DR
IPC: C09D183/04
Filed: 1984-10-31
Granted: 1986-05-22
Abstract: A lacquer system which essentially comprises a silicic acid heteropolycondensate, a flake-shaped or lamellar filler, a solvent and, if appropriate, a conventional synthetic resin for lacquers is suitable for producing anti-corrosion coatings, especially on glass surfaces.
Patent DE-3516983-C1 (DE)
Title: Method and device for indicating a low degree of road grip in motor vehicles
Inventor: BENSINGER JOERG DIPL-ING
IPC: B60R16/02
Filed: 1985-05-10
Granted: 1986-04-03
Abstract: The invention relates to a method and a device for indicating low coefficients of road grip, in particular on icy surfaces, in motor vehicles, in which the actual steering moment of the steering system is detected and compared with a predetermined set steering moment via the speed of the motor vehicle and if the actual steering moment is below the set steering moment a display signal is triggered.
Patent DE-3522497-C1 (DE)
Title: Clamp having a clamping strip for looping around a pipe or the like
Inventor: REINECKE FRANK
IPC: F16L3/11
Filed: 1985-06-24
Granted: 1987-01-02
Abstract: In the case of a clamp (1) having a clamping strip (3) for looping around a pipe or the like, in the case of which the clamping strip has outwardly bent end parts (6, 7), the one end part (6) has an outwardly open, approximately U-shaped incision (8) for the engagement of a clamping screw (15) having a head (16), and the other end part (7) has a slot (10). The other end part is bent back in the circumferential direction of the clamp and is bent around a nut (13) such that it secures the nut in rotation with respect to the thread axis, the threaded shank (17) being inserted through the slot (10) into the nut (13), the nut being supported inside the bent-back end part (7) such that it can rotate about an axis running at right angles to the plane of the clamp, and the clamping-screw head resting on the side of the one end part (6) facing away from the gap between the end parts. In order to simplifying assembly, the clamping-screw head (16) has a conical flange (18) whose maximum diameter is greater than the width of the incision (8) and whose minimum diameter is less than the width of the incision (8).
Patent DE-3545185-C1 (DE)
Title: Luffing-crane jib
IPC: B66C23/82
Filed: 1985-12-20
Granted: 1987-07-23
Abstract: In jibs for luffing cranes, in particular heavy road cranes with a hydraulic luffing device, two luffing cylinders lying side by side are usually used in order to keep as light as possible the crane parts to be removed for road transport on account of weight restrictions applicable to this. The difficulties arising in construction and in handling in particular when connecting the hydraulic connections are avoided by two luffing cylinders being combined with a rigid connection of the two cylinder shells (1) and a common articulation at both ends. The problem-free, simultaneous connection of the hydraulic supply for both luffing cylinders, which is also satisfactory during frequent reconstruction, is especially ensured when the two cylinder shells (1) are made in one piece or are welded or screwed to one another at their ends or are connected to one another by common head and foot pieces (5, 6). <IMAGE>
Patent DE-3717323-C1 (DE)
Inventor: ZOLLER ERNST
IPC: F02M35/08
Filed: 1987-05-22
Granted: 1988-06-23
Abstract: A filter which supplies air to an I.C. engine comprises a housing 2 enclosing an inward flow tubular filter element 3, whose outer surface is cleaned by reverse flow induced by a suction nozzle 10, which extends axially of the element and rotates about axis 17 coincident with that of the element. The element is fixed, and the only rotary seal 20 protects the bearing 18. <IMAGE>
Patent DE-3717891-C1 (DE)
Title: Process and device for producing rotationally symmetrical small parts from glass
Inventor: ANTLINGER HELMUT
IPC: C03B23/00
Filed: 1987-05-27
Granted: 1988-12-08
Abstract: Rotationally symmetrical small parts were hitherto produced from glass by press moulding, which is relatively time-consuming and is uneconomical for the mass production of such small parts. In addition, in the case of small parts produced by press moulding, an undesirable peripheral edge, caused by the material, can be seen. According to the process of the invention, the glass blanks 16 are roll formed in a freely supported manner, with a supply of heat, by means of two profiling rolls 14, 15 driven in the same direction of rotation with a correspondingly high speed. In the process, the glass blanks 16 have to have the same volume before their roll forming as the finished small parts 10. The heat supply takes place intermittently, only shortly before and during the roll forming of a glass blank 16, so that after conclusion of a roll forming, the finished small part 10 can be air cooled and as a result brought into a dimensionally stable state in which it is then ejected by means of an ejector 24 from the gap between the two profiling rolls 14, 15. <IMAGE>