baber/WOPTO huggingface dataset:
Patent DE-602005003362-T2 (DE)
Inventor: DING QINGJIE
IPC: A61K31/4162
Filed: 2005-06-01
Granted: 2008-10-16
Abstract: Novel pyrazolopyrimidines of formula (I): are discussed. These pyrazolopyrimidines are capable of inhibiting the activity of cyclin-dependent kinases, most particularly cyclin-dependent kinase 1 (Cdk1), cyclin-dependent kinase 2 (Cdk2), and cyclin-dependent kinase 4 (Cdk4) and are thus useful, inter alia, in the treatment or control of cancer, in particular solid tumors. This invention also provides pharmaceutical compositions containing such compounds and to methods of treating or controlling cancer, most particularly the treatment or control of breast, lung, colon and prostate tumors.
Patent DE-69021433-T3 (DE)
Inventor: TAKAMURA HIROMI
IPC: C11D3/16
Filed: 1990-05-11
Granted: 1999-03-18
Abstract: A detergent composition comprising an alkylsaccharide surface active agent and a silicone derivative is disclosed. The composition can produce fine, slippery, creamy foam, imparts the least irritation to the skin and hair, a tense, slippery feeling to the hair, and a light, refreshing feeling to the skin. The detergent composition thus can be favorably used as a shampoo and a body shampoo.
Patent DE-69126248-T3 (DE)
Inventor: FAN EUGENE
IPC: G01N33/558
Filed: 1991-02-08
Granted: 2008-01-24
Abstract: The invention disclosed herein relates to the field of one-step assays and latex agglutination tests ("LAT"), and provides an improved method of preparing and using a one-step immunoassay, as well as improved methods of preparing coated latex particles for use in diagnostic assays, and especially, immunochromatographic assays.
Patent DE-69635193-T3 (DE)
Inventor: TSIEN ROGER Y
IPC: C07D311/16
Filed: 1996-06-06
Granted: 2011-03-10
Abstract: Methods and compositions are provided for determining the potential of a membrane. In one aspect, the method comprises: (a) introducing a first reagent comprising a hydrophobic fluorescent ion capable of redistributing from a first face of the membrane to a second face of the membrane in response to changes in the potential of the membrane, as described by the Nernst equation, (b) introducing a second reagent which labels the first face or the second face of the membrane, which second reagent comprises a chromophore capable of undergoing energy transfer by either (i) donating excited state energy to the fluorescent ion, or (ii) accepting excited state energy from the fluorescent ion, (c) exposing the membrane to radiation; (d) measuring energy transfer between the fluorescent ion and the second reagent, and (e) relating the energy transfer to the membrane potential. Energy transfer is typically measured by fluorescence resonance energy transfer. In some embodiments the first and second reagents are bound together by a suitable linker. In one aspect the method is used to identify compounds which modulate membrane potentials in biological membranes.
Patent DK-1052249-T3 (DK)
Inventor: STAEBLER FLORIAN
IPC: C07D233/74
Filed: 2000-05-05
Granted: 2003-12-01
Abstract: The present invention provides an improved process for preparing an hydroxycarbamoyl derivative of a carboxylic acid using a hydroxylammonium salt of a carboxylic acid as a reagent.
Patent DK-1155224-T3 (DK)
Inventor: INMAN MICHAEL
IPC: B01D53/32
Filed: 2000-02-21
Granted: 2003-08-18
Abstract: A power supply and control system for a motor vehicle incorporating a plasma-assisted reactor for treatment of exhaust emissions and including a power source for supplying first and second output voltages.
Patent DK-1222004-T3 (DK)
Inventor: WALTER LEA
IPC: A62B35/00
Filed: 2000-10-19
Granted: 2006-05-01
Abstract: The invention relates to a work safety and rescue suit comprising an overall (1). Straps, (2a, 2b, 3, 5) permanently sewn on to the overall in the thigh, buttock and armpit regions, are connected to four removable straps (6a, 6b, 8a, 8b) on the front of the overall by means of fixing rings (5a, 5b, 7a, 7b) and, on the front, two further removable straps from the thigh region are connected to the other four removable straps (6a, 6b, 8a, 8b) by means of two removable fixing rings (10a, 10b) in the breast region.
Patent DK-1250206-T3 (DK)
Inventor: FANG X DANIEL
IPC: B23B51/00
Filed: 2001-01-24
Granted: 2011-06-27
Abstract: A cutting tool or drill insert with chip control geometry comprising a body including a portion securable in a holder and a forward portion. The forward portion defining at least one cutting edge extending from the central axis of the body to an edge of the body. A chip groove is defined by the surface of the body adjacent to the cutting edge. The chip groove incorporates chip control geometry as spaced apart elongate projections.
Patent DK-1252164-T3 (DK)
Inventor: KAMMERMEIER THOMAS
IPC: A61P7/02
Filed: 2001-01-26
Granted: 2004-07-05
Abstract: The present invention relates to a process process for the preparation of the compound of the formula I  where the compound of the formula III  is reacted with oxalyl chloride and the product obtained is treated with hydrazine and an alkali metal hydroxide in the aqueous phase at elevated temperature, after treatment is complete a three-phase system is produced by addition of an ether and the compound of the formula I is obtained by acidifying the middle phase. The invention moreover relates to a polymorph of the compound of the formula I.
Patent DK-1268399-T3 (DK)
Inventor: BINDER THOMAS P
IPC: C07C227/40
Filed: 2001-03-15
Granted: 2004-12-06
Abstract: This invention relates to a method for separating basic amino acids from fermentation broth comprising contacting the broth with strong acid cation exchange resins that have a low degree of cross-linkage and eluting the amino acid. The method described herein results in higher yield and higher purity of lysine, in addition to higher throughput, as compared to conventional processes of purification of lysine from fermentation broth.
Patent DK-1282636-T3 (DK)
Inventor: MARGOLSKEE ROBERT F
IPC: C07K19/00
Filed: 2001-04-17
Granted: 2009-11-23
Abstract: The present invention relates to the discovery, identification and characterization of a transient receptor potential channel, referred to herein as TRP8, which is expressed in taste receptor cells and associated with the perception of bitter and sweet taste. The invention encompasses TRP8 nucleotides, host cell expression systems, TRP8 proteins, fusion proteins, polypeptides and peptides, antibodies to the TRP8 protein, transgenic animals that express a TRP8 transgene, and recombinant “knock-out” animals that do not express TRP8. The invention further relates to methods for identifying modulators of the TRP8-mediated taste response and the use of such modulators to either inhibit or promote the perception of bitterness or sweetness. The modulators of TRP8 activity may be used as flavor enhancers in foods, beverages and pharmaceuticals.
Patent DK-1360164-T3 (DK)
Inventor: UZUN ISA
IPC: C07C51/41
Filed: 2001-11-08
Granted: 2005-01-31
Abstract: This invention relates to a process for the continuous production of potassium formate by the reaction of formaldehyde present in the reactor outlet gas in formaldehyde production plants with an aqueous solution of potassium hydroxide, wherein the formaldehyde is in gaseous monomeric form, the formaldehyde being fed to the reaction column at a temperature of 100° C. and above. By this invention, a straightforward method of potassium formate production and removal of excess reactant(s) are realized very efficiently. Pure potassium formate solution at any strength is produced. The strength of the product solution depends on where it will be used. Potassium Formate solution is used mainly as deicer, drilling mud, and/or in the production of flaked or granular Potassium Formate by appropriate methods. The flaked and granular Potassium Formate in turn is used in the fields mentioned above and also as an additive to animal feed.
Patent DK-1436420-T3 (DK)
Inventor: GIANNOULA SOUFLA
IPC: C12Q1/68
Filed: 2002-10-03
Granted: 2007-09-10
Abstract: Dipping test strip assay system, method for the construction of said test strip system, and method for the detection and/or determination of specific nucleic acid sequences by the use of assay hybridization protocols developed on said test strip system. Colloidal gold particles conjugated to oligonucleotides are dried on the strip, and the protein Streptavidin, as well as an oligonucleotide is immobilized at the membrane area of the strip. A specific nucleic acid sequence is detected when a visible signal indicative of the presence or absence of the analyte is developed at the region of the Streptavidin's immobilization, while the completion of the assay is confirmed by the development of a visible signal at the region of the oligonucleotide's immobilization. The dipping test strip assay system is useful for the rapid detection or determination of specific nucleic acid sequences in a sample, such as specific viral or bacterial nucleic acid sequences, as well as mutated DNA sequences of clinical significance, after the amplification of the specific nucleic sequence in the sample through a PCR reaction.
Patent DK-1494629-T3 (DK)
Inventor: BARDER JAMES HENRY
IPC: A61F6/04
Filed: 2003-04-14
Granted: 2007-06-11
Abstract: A condom has a vasodilator active compound applied to its external surface, preferably disposed towards the open end of the condom whereby, in use during intercourse, the compound makes contact with the vaginal meatus or proximal region of the vagina, such that the vasodilator is absorbed though the lining of the vagina to stimulate and increase the flow of blood in the labia and through the clitoris to promote engorgement thereof to alleviate symptoms associated with female inorgasmia
Patent DK-1481059-T3 (DK)
Inventor: GRAY JEFF
IPC: C12Q1/68
Filed: 2003-02-13
Granted: 2009-01-12
Abstract: The present invention generally relates to methods and compositions for expressing proteins or polypeptides in prokaryotic hosts using eukaryotic signal sequences.
Patent DK-1606307-T3 (DK)
Inventor: SUI ZHIHUA
IPC: A61P15/18
Filed: 2003-07-02
Granted: 2008-01-21
Abstract: The present invention is directed to novel estrieno[3,2-b]/[3,4-c]pyrrole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and diseases mediated by an estrogen receptor.
Patent DK-1653483-T3 (DK)
Inventor: HAMACHER HEINZ-WILLI
IPC: H01B7/04
Filed: 2004-10-29
Granted: 2007-03-05
Abstract: The cable has a central supporting unit surrounded by a set of wires, where the supporting unit consists of a turn-free steel cable, which is provided with an outer insulating layer. The steel cable has a core wire (6), a layer of a set of wires (7) ropped on the wire (6), and another layer of wires (10) rolled on the former layer. Standard direction and length of the two layers deviate from each other.
Patent DK-1648880-T3 (DK)
Inventor: KYLE DONALD J
IPC: C07D213/85
Filed: 2004-07-30
Granted: 2010-05-10
Abstract: Compounds of formulae (I) and (II) where X is S or O and Ar 2 , R 1 , R 2 , R 3 , R 8 , n, m, and t are disclosed herein, or a pharmaceutically acceptable salt thereof (a "3-substituted Pyridyl Compound"), compositions comprising an effective amount of a 3-substituted Pyridyl Compound, and methods for treating or preventing pain, urinary incontinence, an ulcer, inflammatory-bowel disease, irritable-bowel syndrome, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia or depression in an animal comprising administering to an animal in need thereof an effective amount of a 3-substituted Pyridyl Compound are disclosed herein.
Patent DK-1715762-T3 (DK)
Inventor: DOAT STEPHANE
IPC: A23L33/15
Filed: 2005-02-01
Granted: 2008-01-28
Abstract: Producing a dairy product on a production line comprising continuously injecting a molten sterol or stanol ester into a milk-based composition containing milk protein but no emulsifier and then homogenizing the mixture,is new. During injection, the temperature (T 2) of the composition is at least equal to the temperature (T 1) of the molten sterol or stanol ester. Independent claims are also included for: (1) product produced as above; (2) apparatus for carrying out the above process, comprising means for maintaining the ester at T 1, e.g. an insulated or thermostatted tank; means for passing the ester to the feed system of the production line while maintaining the ester at T 1, e.g. an insulated pipe; and means for introduing the ester at T 1 into the production line, e.g. a pump.
Patent DK-1740206-T3 (DK)
Inventor: FOSTER SIMON J
IPC: C07K16/00
Filed: 2005-04-08
Granted: 2011-10-17
Abstract: The present invention relates to antigenic polypeptides expressed by pathogenic microbes, including antigenic polypeptides encoded by the nucleic acid sequence of FIG. 1, vaccines comprising the antigenic polypeptides and therapeutic antibodies directed to the antigenic polypeptides.
Patent DK-1935145-T3 (DK)
Inventor: FARKAS JANOS
IPC: H04L45/48
Filed: 2005-10-11
Granted: 2012-04-10
Abstract: A method for generating spanning trees (ST1,ST2,ST3) in a network (NW2). The network has nodes (A-K) interconnected by links (L2) and the trees are used for handling link and node failures. For handling link failures there is for each link (L2) at least one tree (ST1,ST2) that does not include that link. For node failures there is for each node (A-K) at least one spanning tree (ST1-ST3) to which the particular node is connected by a single link (L2). The first spanning tree (ST1) connects all nodes (A-K) and from each node one link is left unconnected. The second tree (ST2) includes all nodes and all the unconnected links. None of the links is included in both the trees (ST1,ST2). If node B is broken, node A cannot communicate with nodes C and D so the third tree (ST3) is needed. The method has the advantage of giving a low number of trees also for big networks of any topology and can be implemented off-line.
Patent DK-1824641-T3 (DK)
Inventor: SCHAER ANDREAS
IPC: B25B1/18
Filed: 2005-11-23
Granted: 2011-03-28
Abstract: This invention relates to a clamping element for workpieces, in particular a vice (10, 33, 40), comprising a first clamping jaw (12, 34, 41) and a second clamping jaw (13, 35, 42), which are mounted on a carriage bed (11). To avoid bending moments as a result of tensile forces acting on the carriage bed (11), the clamping element of the invention is characterized in that the resultants of the forces introduced by the clamping jaws (12, 13, 34, 35, 41, 42) into the carriage bed (11) as a result of the clamping forces acting on the clamping jaws (12, 13, 34, 35, 41, 42) are located in the plane of the neutral fiber (32) of the carriage bed (11). Preferably, the clamping jaws (12, 13, 41, 42) constitute two-armed levers, a clamping surface (21, 24) being associated to the one lever arm and a push rod (27, 46) engaging the other lever arm.
Patent DK-1853308-T3 (DK)
Inventor: FICHTNER DIETER
IPC: A61K9/00
Filed: 2005-12-13
Granted: 2012-06-25
Abstract: The present invention is directed to a pharmaceutical preparation for oral application for treatment of fish, in particular for vaccination of fish of the salmon family and other fish having a comparable digestive system against bacterial and/or viral infections, in particular against VHS and IHN. The invention is also directed to a method for producing the preparation.
Patent DK-1819729-T3 (DK)
Inventor: HABERMANN PAUL
IPC: A61K38/22
Filed: 2005-11-18
Granted: 2009-08-17
Abstract: The invention relates to the production of carboxy-terminal (C-terminal) amidified peptides with C-terminal amidified lysin, in particular with the biological activity of GLP-1, the chemical and/or biotechnological precursors and intermediate products thereof. The invention also relates to a method for the production and use thereof for producing pharmaceutical products.
Patent DK-1905206-T3 (DK)
Inventor: FAGERLIN PETER
IPC: H04B1/58
Filed: 2006-07-14
Granted: 2011-02-21
Abstract: The inventive communication device for converting a baseband data signal to a baseband signal for a coaxial cable, comprises at least one first input terminal for receiving an incoming baseband data signal, at least a first output terminal for outputting an outgoing baseband data signal, a first input/output terminal for connecting to a coaxial cable for communication of a duplex signal, first rebalancing means for converting said incoming baseband data signal to a balanced input signal, subtraction means for subtracting the balanced input signal from the duplex signal to obtain a balanced output signal, second rebalancing means for converting the balanced output signal to said outgoing baseband data signal.
Patent DK-1990070-T3 (DK)
Inventor: FANGROW THOMAS F JR
IPC: A61M39/02
Filed: 2005-11-04
Granted: 2012-04-10
Abstract: A soft grip medical connector comprises a housing with an upstream end, a downstream end and a lumen extending through a central portion thereof. A flexible member comprises a valve portion integrally formed with a sleeve portion. The valve portion is positioned within a section of the housing and is configured to control a flow of fluid through the housing lumen. The sleeve is inverted to envelope at least a portion of the outer surface of the housing. In some embodiments the gripping portion is integrally formed with the valve portion. In some embodiments, the connector is also generally configured to create a positive pressure in a catheter lumen upon removal of a syringe or other medical device from the upstream end of the connector. Methods of making a medical fluid connector generally comprise forming a valve member with a sleeve extending there from, and assembling the valve, sleeve and housing.
Patent DK-2162475-T3 (DK)
Inventor: MORSCHBACKER ANTONIO LUIZ RIBEIRO DE CASTRO
IPC: C08F210/16
Filed: 2008-12-05
Granted: 2011-11-21
Abstract: An ethylene-butylene copolymer prepared from integrated processes for the production of ethylene-butylene copolymers produced from at least one renewable natural raw material, wherein, in the ethylene monomer used in the polymerization of the ethylene copolymer with 1-butylene, as the comonomer, ethylene is obtained by the ethanol dehydration reaction, in which ethanol is produced by the fermentation of sugars, and the 1-butylene comonomer is obtained according to at least one of dehydration reactions involving 1-butanol and the dimerization reaction of ethylene produced by the dehydration of ethanol obtained from the fermentation of sugars, followed by the isomerization of the 2-butylene isomers then formed. The ethylene-butylene copolymer thus produced is completely based on carbon atoms originated from renewable natural raw materials which, upon incineration, produce CO2 from a non-fossil origin.
Patent DK-2968286-T3 (DK)
Inventor: KAUFMAN MICHAEL D
IPC: C07D405/14
Filed: 2014-03-14
Granted: 2018-01-02
Abstract: Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-IR), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c- FMS, c-KIT, or PDGFR kinases.
Patent DK-0413250-T3 (DK)
Inventor: CASTELLANA FRANK S
IPC: A61F5/448
Filed: 1990-08-08
Granted: 1994-11-21
Abstract: Occlusive attaching means comprising a first relatively thick adhesive component (A) to be secured to the skin around the stoma and a relatively thin flexible second adhesive component (C) to be secured to the skin at a distance from the stoma. Both adhesive components (A,C) include an occlusive adhesive layer (11,31) formulated as a blend containing one or more water soluble or swellable hydrocolloids dispersed in polyisobutylene along with other optional ingredients. The attaching means can be utilized as part of a one or two-piece ostomy system.
Patent DK-0378265-T3 (DK)
Inventor: NOOMEN ARIE
IPC: C08G12/40
Filed: 1990-01-08
Granted: 1994-09-19
Abstract: A low-temperature curable composition is provided which is based upon a polyaromatic aldehyde group-containing compound and a ketiminized polyamino compound. These compositions display good stability, extended potlife, and a good balance of physical and mechanical properties making them suitable for a wide variety of coating, impregnating, sealing and bonding application.
Patent DK-0504214-T3 (DK)
Inventor: SINGH TEJ KULDIP
IPC: D04H1/68
Filed: 1990-12-05
Granted: 1995-04-10
Abstract: PCT No. PCT/GB90/01895 Sec. 371 Date Jun. 4, 1992 Sec. 102(e) Date Jun. 4, 1992 PCT Filed Dec. 5, 1990 PCT Pub. No. WO91/08037 PCT Pub. Date Jun. 13, 1991.A method of producing a particulate-solid-bearing air-permeable sheet of material of other than woven and knitted material selected from non-woven fabrics and open cell foam materials includes the following steps: entraining a particulate solid in a gaseous carrier in the substantial absence of fibrous material; disposing one face of a preformed air-permeable sheet material, which material has a density at or below 0.25 g/cm3, in the path of a stream of the gaseous carrier and entrained particulate solid, whilst maintaining a pressure drop across the thickness of the preformed air-permeable sheet material from the one face to the other face of the air-permeable sheet material, whereby to entrap some or all of the entrained particulate solid on or on and in the air-permeable material; and fixing the retained particulate solid on or on and in the air-permeable material with a binder. The mean pore size of the preformed sheet material is greater than the mean particle size of the particulate solid.
Patent DK-0484517-T3 (DK)
Inventor: MATKOVICH VLADO I
IPC: A61K35/14
Filed: 1991-05-24
Granted: 1996-03-11
Abstract: A biological fluid processing system (10) for the processing of biological fluid (such as blood) is disclosed. The biological fluid processing system (10) separates gases from the system to improve storage life, safety, and the quality of the processed biological fluid. The biological fluid processing system (10) increases the yield of the processed biological fluid by allowing recovery of biological fluid trapped in various elements of the system. A typical biological fluid processing system (10) includes a collection bag (11) with conduits (12, 15) connecting it to a second container (17) for receiving biological fluid. A functional biomedical device (14) may be included. A gas inlet (13) allows gas to be introduced into the system to recover the biological fluid trapped in the system. A gas outlet (16) allows gas to be purged from the system. <IMAGE>
Patent DK-0546062-T3 (DK)
Inventor: IMSGARD FINN
IPC: B27K3/10
Filed: 1991-08-30
Granted: 1996-06-24
Abstract: A method and a device serve to locally impregnate a piece of wood (6) with a gaseous or liquid wood impregnation agent, which is injected under pressure by means of an injection apparatus (70) into a hole (7), which is drilled in the wood and closed with a valve (44) defining a cavity (10). To obtain the greatest possible propagation of the impregnation agent in the wood the air of the cavity (10) is first removed either by flushing the cavity with impregnation agent or directly evacuating the cavity of air. The device comprises an elastomeric valve (44) having at least one internal valve channel (42, 63) which is clamped tightly together along a portion in the longitudinal direction when the valved is pressed into the drilled hole, as well as an injection apparatus having a needle associated with each valve channel to drive into the respective valve channel upon injection and thereby connect the injection apparatus with the hole. The valve channels are closed with pins after the injection, which are provided on a disc that changes its colour after a predetermined period of time of e.g. 3 years to indicate that impregnation should be repeated.