baber/WOPTO huggingface dataset:
Patent NO-170419-B (NO)
Inventor: FABRE JEAN-LOUIS
IPC: A61K31/435
Filed: 1987-07-02
Abstract: A compound of the general formula I;    <IMAGE>  (I)  in which R is hydrogen or a halogen or an alkyl, alkyloxy, alkylthio, trifluoromethyl, amino, alkylamino, dialkylamino, hydroxy, cyano, carboxy, alkylsulphinyl, alkylsulphonyl, sulphamido, alkylsulphamido, dialkylsulphamido, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, phenylcarbamoyl, diphenylcarbamoyl, pyridylcarbamoyl, dipyridylcarbamoyl, benzyl, alkylcarbonyl, benzoyl, alkyloxycarbonyl, phenoxycarbonyl, alkylcarbonyloxy, benzoyloxy, alkylcarbonylamino, benzamido, phenyl, phenoxy or phenylthio group, X is oxygen or sulphur or an imino, alkylimino, phenylimino, benzylimino, sulphinyl, sulphonyl, carbonyl, carbonylmethylene, methylenecarbonyl, carbonylvinylene or vinylenecarbonyl group, or X represents a valency bond or a straight-chain alkylene group containing 1 to 4 carbon atoms and Ar is a phenyl, naphthyl, pyridyl, quinolinyl, isoquinolinyl, thienyl, benzothienyl, thieno[3,2-b]thien-2-yl or thieno[2,3-b]thien-2-yl group, it being possible for the group Ar to be unsubstituted or substituted with one or more halogen or alkyl, alkyloxy, alkylthio, trifluoromethyl, amino, alkylamino, dialkylamino, hydroxy, cyano, carboxy, alkylsulphinyl, alkylsulphonyl, sulphamido, alkylsulphamido, dialkylsulphamido, carbamoyl, alkylcarbamoyl, dialkylcarbamoyl, phenylcarbamoyl, diphenylcarbamoyl, pyridylcarbamoyl, dipyridylcarbamoyl, benzyl, alkylcarbonyl, benzoyl, alkyloxycarbonyl, phenoxycarbonyl, alkylcarbonyloxy, benzoyloxy, alkylcarbonylamino or benzamido group; each alkyl moiety containing 1 to 4 straight- or branched-chain carbon atoms; the compound being in separate enantiomeric form or mixtures thereof or a pharmaceutically acceptable salt thereof is useful in the treatment of all the pathological conditions in which PAF-acether may be directly or indirectly implicated.
Patent NO-173011-B (NO)
Inventor: JARREAU FRANCOIS-XAVIER
IPC: C07J41/00
Filed: 1988-09-30
Abstract: The invention relates to androstane-17-carboxylic acid esters, represented by general formula (I):   <IMAGE>   wherein R1 represents a lower alkyl group containing 1 to 4 carbon atoms, a lower alkyl group containing 2 to 4 carbon atoms substituted by an amino group, or an aralkyl group from 6 to 12 carbon atoms, R2 and R3, which may be the same or different, represent a hydrogen atom or a lower alkyl group containing 1 to 4 carbon atoms, R4 represents a hydrogen atom, a hydroxy group or an acetoxy group, R5 represents a hydroxy or acetoxy group, or R4 and R5 represent together a divalent alkylenedioxy group, R6 represents a hydroxy group, a methoxy group, or an acetoxy group, R7 represents a methyl group or a hydroxymethyl group, R8 represents an hydrogen atom or a hydroxy group and <IMAGE>  represents either a   <IMAGE>  group or a   <IMAGE>  carbon atom having the double linkage in the 4- or 5-position of the steroid nucleus. Such esters are prepared by coupling reaction of the corresponding 14-azido-derivatives with a sugar, followed by a reduction. Application in therapy, especially in the treatment of heart failure.
Patent NO-178606-B (NO)
Inventor: ROHRBOUGH JOHN
IPC: A61J1/00
Filed: 1990-09-11
Abstract: A bipartite injector device (1 sec ) having parts which can be simply assembled utilizing a snap fit arrangement, allowing for low cost production and assembly of parts which can be accurately aligned and connected in a fluid tight manner. The injector device includes a hollow outer shell (2 sec ) having a front closed end (3 sec ) with a hub (5 sec ) extending through the closed end (3 sec ) to a forward position exterior of the shell and terminating in a nozzle (7 sec ). A bore extends through the hub (5 sec ) and nozzle (7 sec ). A cylindrical inner sleeve (20 sec ) is mounted within the hollow shell (2 sec ) in a cantilever manner by means of snap fit locking. The inner sleeve (20 sec ) is formed with a rearward facing tubular spike (55) and a flow passage (27 sec ) extends through the spike (55) such that the flow passage is connected in a fluid tight manner to the bore in the hub (5 sec ) and nozzle (7 sec ) when the inner sleeve (20 sec ) is mounted in the outer shell (2 sec ). The injector device is adapted to receive a cylindrical medicament vial (40 sec ) in the rear open end (4 sec ) of the outer shell (2 sec ). The vial (40 sec ) has an open end (41 sec ) closed by a penetrable stopper (42 sec ) which may be penetrated by the spike (55) in the inner sleeve (20 sec ) to allow fluid tight flow between the vial (40 sec ) and the nozzle (7 sec ). The nozzle (7 sec ) may be connected to a separate charging, mixing or dispensing device (51) by a means of a luer connection (9 sec ,67).
Patent SE-313598-B (SE)
Inventor: HOFFMANN H
IPC: H04R1/22
Filed: 1965-07-29
Abstract: 1,082,433. Electro-acoustic transducers. SIEMENS A.G. July 28, 1965 [July 29, 1964 (2)], No. 32217/65. Heading H4J. A microphone has apertures 10 and 11, coupling a resonator chamber formed behind the diaphragm with further chambers 12 and 13, in which the coupling apertures are covered with an attenuating material formed by the capillary zone of an ionotropic capillary membrane. A further coupling aperture 16 may be provided in the diaphragm itself, in which case the diaphragm is preferably formed of a primary carrier on which the capillary zone is formed, e.g. by subjecting polyelectrolytes to ion exchange, as described in Specification 918,626, the primary carrier being removed in the area of the aperture 16.
Patent YU-48715-B (YU)
Inventor: JOHANNES BAECKSTROEM REIJO
Filed: 1991-08-12
Abstract: Derivati katehola prema opštoj formuli I u kojoj je R1 nitro ili cijano grupa ili halogen i R2 je grupa odabrana od gde su X1, X2, Y i Z nezavisno kiseonik, sumpor ili NR gde je R vodonik, alkil od 1-8 uhljenikovih atoma, cikloalkil od 5-7 ugljenikovih atoma, fenil C1-8 alkil (C1 do 8 alkil) i fenil grupa njihove soli ili njihovi estri. - Prijava sadrži još 1 nezavisan i 15 zavisnih zahteva.
Patent YU-48433-B (YU)
Title: Novi derivati benzoeve i fenilsirćetne kiseline j
Inventor: ALIG
IPC: A61K/
Filed: 1989-12-06
Abstract: Ra)-(CH2)n-NH-Rb (R1) Ra označava H, NH2, -NHCOO-C1-4-alkil, -NH-Z ili -NHCOCH2N(Y)-CH2CH2NH-Y, i n iznosi 1-6 ili, ako Ra označava H, n takodje može iznositi i O, Y označava H, Boc ili Z, Rb označava H, amidino ili -C(NH)-(CH2)0-3-CH3), Rc označava H ili amidino, T označava -CH2-, -CH=CH- ili -C(H,Rd)-CH2-, Rd ima isto značenje kao i Ra ili označava -NHCO-fenil, NHCO-fenilen-N3 ili -NHSO2-aril, R0 označava H ili amidino, R3 označava H, -CONH2, -CORf, COORg ili aril, Rf označava ostatak alfa-aminokarbonske kiseline (koja je vezana preko amino grupe) ili ostatak nekog njenog estra ili amida, Rg označava H ili niži alkil, R2 označava H, CH3, OCH3, NO2, halogen, NH2, NHCO-fenilen-COOH, -NHCO(CH2)1-4-COOH, ORh, -CH2CH2ORh, -CH2CH2OCH2CH2ORh, ili -CH2COORh, i Rh označava H ili niži alkil, kao i hidrati ili solvati i fiziološki primenljive soli ovih jedinjenja. - Prijava sadrži još 3 nezavisna i 15 zavisnih zahteva.
Patent RS-51903-B (RS)
Inventor: NERURKAR MANOJ
IPC: A61K47/48
Filed: 2003-08-14
Abstract: FORMULACIJA ARIPIPRAZOL KOMPLEKSA I POSTUPAK. Inkluzioni kompleks aripiprazola u supstituisanom beta-ciklodekstrinu.Prijava sadrži još 19 patentnih zahteva.
Patent ZA-796575-B (ZA)
Title: Gas filter
Inventor: PLATTEEUW P
IPC: B01D46/06
Filed: 1979-12-04
Abstract: In a gas filter, especially a room air filter (1) comprising a rectangular frame (2), a replaceable filter pack (4) which includes a filter web (7) arranged in zig-zag fashion to form a plurality of filter pockets disposed in side-by-side relationship which is mounted between peripheral walls is adapted to be received within the frame by a supporting grid structure (3) which is mounted within the frame and shaped to match the plies of the filter web. 
<??>In order to provide a gas filter which is easy to handle and whose filter pack can also be transported without causing any trouble even, when it is in contaminated condition all peripheral walls (8, 9, 10 and 11) of the filter pack are stiff and jointly define a rigid container, the gas inlet opening (13) of this container being adapted to be closed by folding and bending marginal portions (R) of the peripheral walls (8, 9, 10 and 11) adjacent to this opening, and plies (21) provided adjacent the gas outlet opening (14) are held by tensioning means (22) which extend in the direction of the plies and are anchored to opposed peripheral walls (8, 10).
Patent ZA-816077-B (ZA)
Title: Production of phosphorus pentoxide
Inventor: DANIEL HELLMUTH
IPC: C01B25/12
Filed: 1981-09-02
Abstract: The invention relates to process for making phosphorus pentoxide by subjecting elementary phosphorus to a combustion reaction with the aid of air, the reaction heat being utilized for the production of energy. To this end, the invention provides for the phosphorus to be subjected to combustion with dry air containing, per m3, 5 g down to 0.01 g of water, inside a combustion chamber of which the metallic walls are arranged so as to form a cooling system with cavities therein and for a liquid and liquid/steam-mixture, respectively, to be circulated through the cooling system under pressure within the range 1 to 150 bars, the liquid or mixture assuming a temperature of more than 150 DEG  C. up to 500 DEG  C. Steam which is formed in the cooling system is continuously taken therefrom and replaced by an equivalent proportion of fresh liquid.
Patent ZA-818499-B (ZA)
Title: Agents for combating circulatory illnesses and their use
Inventor: JUNGE B
IPC: C07D235/00
Filed: 1981-12-08
Abstract: The invention relates to pharmaceutical compositions containing active ingredients of Formula (I) and methods for the use of said compositions to treat cardiac insufficiencies. Also included in the invention are methods of the manufacture of said active ingredients of Formula (I). The invention includes, additionally, compounds of Formula (I).
Patent ZA-824084-B (ZA)
Title: Smoke detector containing a radiation source operating in a pulse mode
Inventor: MUGGLI JUERG
IPC: G01N21/53
Filed: 1982-06-10
Abstract: A smoke detector contains a pulse-operated radiation source and a radiation receiver arranged externally of the region directly irradiated by the radiation source. The radiation receiver, in the presence of smoke in the radiation region, is impinged by scattered radiation and delivers output pulses. There is provided an evaluation circuit which generates a blocking pulse, and which inputs a resetting signal to a counter device in consequence of the difference of the blocking pulse and output pulse of the radiation receiver. The counter or counting device, in the absence of a resetting signal, is switched further and upon reaching a predetermined counter state triggers an alarm signal. High-frequency electrical disturbances which arise, as long as the radiation source delivers radiation pulses, at most can generate an additional resetting signal for the counter, so that the integrity of the smoke detector against triggering of false alarms is enhanced. If there is connected in parallel to the radiation receiver a NTC-resistor, then there is obtained a smoke detector which responds to a further combustion criterion (temperature).
Patent ZA-858302-B (ZA)
Title: Arrangement of work locations
Inventor: PRIESEMUTH WOLFGANG
IPC: B23Q41/02
Filed: 1985-10-29
Abstract: A ring-shaped arrangement of individual work locations. Tables which are preferably trapezoidal are arranged in a ring, in the middle of which is disposed a region which is free of table tops, and in which can be disposed common supply lines or the like. The individual work locations, which are arranged around the central region, are respectively separated from an adjacent table by a vertical partition in which is disposed a material-transfer opening. The supply of material to the individual work locations can be effected from supply bins disposed on a shelf supported above the ring-shaped table top on the upper edges of the radially directed partitions. If it is a question of small parts, the latter can be transferred to the work location via conveying tubes, which lead from the supply bins on the shelf to the table top of the individual work locations.
Patent ZA-862725-B (ZA)
Title: Heterocyclic amide derivatives
Inventor: HOLMWOOD GRAHAM
IPC: A01N43/653
Filed: 1986-04-11
Abstract: Novel heterocyclic amide derivatives of the formula    <IMAGE>  (I) in which R1 represents alkyl, or represents alkenyl which has more than 2 carbon atoms and is optionally substituted by halogen, or represents alkinyl which has more than 2 carbon atoms and is optionally substituted by halogen, or represents alkoxyalkyl or alkylthioalkyl; R2 represents optionally substituted naphthyl, or represents optionally substituted tetrahydronaphthyl, or represents optionally substituted indanyl; A represents an alkylene bridge, or also an alkenylene bridge if X denotes a direct bond; X represents oxygen, sulphur or a direct bond; Y represents oxygen or sulphur; B represents imidazol-1-yl, pyridin-3-yl, pyrazin-2-yl, pyrimidin-5-yl, 1,2,4-triazol-1-yl or 1-methyl-imidazol-5-yl-; and their acid addition salts and metal salt complexes, are outstandingly active as fungicides.
Patent ZA-871487-B (ZA)
Title: A nail strip
Inventor: STEFFEN MARKUS
IPC: B25C1/00
Filed: 1987-03-02
Abstract: 1. A nail strip (1) having nails which are held together in parallel arrangement mutually by way of severable connecting means (8), in which respect the nails are held in guide bushes (4) having guidance regions which are circular in axial projection of the nails and the guide bushes (4) are connected together by way of the connecting means (8) projecting radially beyond the guidance regions in their axial direction, characterised in that the guidance regions are formed by annular surfaces (5) which are provided in both axial end zones of the guide bushes (4) and the diameter of which exceeds the diameter of the portion, lying between the annular surfaces, of the guide bushes (4) as well as of the head (3) of the nails.
Patent ZA-876377-B (ZA)
Title: Device to feed clips step-by-step for the automatic connection of rails to sleepers
IPC: B23P19/00
Filed: 1987-08-26
Abstract: Device to feed clips step-by-step for the automatic connection of rails to sleepers, which is suitable to be fitted to machines or units delivering connecting and clamping components and/or to machines which screw the rails to the sleepers, and is able to deliver the clips (12) directly to previously installed bolts (15) located at the sides of the rails, or to means w hich carry out prior installation of the bolts, or to means which position beforehand the connecting and clamping components, a chute (11) being provided along which such clips (12) slide by gravity, the device comprising a conditioner assemblage (27) that intercepts the clips (12), allows them to pass and clamps them,in which device the chute (11) is upheld resiliently (19) and the conditioner assemblage comprises at an end position (12A) resiliently governed wheels (20) which cooperate with the back of the clip (12) in retaining momentarily the clip (12), and also comprises a toothed wheel (16) to control the feed of the clips (12) and to expel the same (12) when they do not hook themselves onto a bolt (15).
Patent ZA-878672-B (ZA)
Title: Acryuc acid derivatives
Inventor: ANTHONY VIVIENNE MARGARET
IPC: C07D521/00
Filed: 1987-11-19
Abstract: Compounds of the formula : <CHEM> and stereoisomers thereof, wherein R<1> and R<2>, which are the same or different , are hydrogen, cyano or halogen (fluorine, chlorine, bromine or iodine) or optionally substituted alkyl; V is either oxygen or sulphur; W, X, Y and Z, which may be the same or different, are hydrogen, halogen, nitro, cyano, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted aralkyl, optionally substituted aryl, optionally substituted aryloxy, optionally substituted alkoxy, optionally substituted arylalkoxy, optionally substituted alkenyl S(O)nR<3> (wherein n is 0, 1 or 2), or optionally substituted heteroaryl, or W, X or X, Y or Y, Z together form methylenedioxy; and R<3> is optionally substituted alkyl, optionally substituted aryl, optionally substituted aralkyl or optionally substituted heteroaryl. The compounds are useful as fungicides and also as plant growth regulators, insecticides and miticides.
Patent ZA-904226-B (ZA)
Title: Rubber compositions having improved processability
Inventor: LYNCH ERIC ROYLE
IPC: C08L7/00
Filed: 1990-06-01
Abstract: Alkylthioalkanoic acids, salts or esters having the formula  R<1>S(CR<3>R<4>)xCO2R<2> where R<1> represents an alkyl or alkenyl group, or a hydroxy- or alkoxy- substituted alkyl or alkenyl group, said group containing (apart from the alkoxy carbon atoms in an alkoxy-substituted alkyl or alkenyl group) from 4 to 22 carbon atoms, R<2> represents hydrogen, a metallic or other cationic group, or an esterifying group, each of R<3> and R<4> represents independently hydrogen or an alkyl group, and x has a value of from 1 to 10, act as viscosity-modifying agents in unvulcanised rubber compositions. Compared with conventional processing aids, they improve the processing characteristics of unvulcanised rubber compositions and can have beneficial effect on the physical properties of vulcanisates obtained by the vulcanisation of such compositions.
Patent ZA-918347-B (ZA)
Title: Flame retardant concentrates and process for their preparation
Inventor: BERTELLI GUIDO
IPC: C09K21/14
Filed: 1991-10-18
Abstract: Concentrate of a flame retardant additive, in the form of nonextruded particles, each one comprising:   A) a matrix of a nonextruded, as polymerized particle, preferably spheroidal, of a polymer or copolymer of olefins having porosity greater than or equal to 15%, expressed as a percent of the void volume on the total volume of the particle, B) the product of reaction between bismuth or antimony trichloride or tribromide, or their mixtures, and one or more amines; wherein said product (B) is made "in situ" and deposited on the surface of the matrix and inside the pores thereof. d
Patent ZA-927074-B (ZA)
Title: Corrugated paper board production and apparatus therefor.
Inventor: MCKINLAY PETER ROBERT
IPC: B31F1/28
Filed: 1992-09-16
Abstract: The invention relates to an improved method and apparatus for producing paper board structures wherein two corrugated mediums are bonded together at their flute tips. End gears (16a, 16b, 15a, 15b) are provided, at least, on the ends of the corrugating rolls (4, 6) which provide tip to tip bonding. The end gears may be abutting or non abutting and may be provided on both ends of the corrugating rolls, which assist tip to tip bonding.
Patent ZA-931895-B (ZA)
Title: Automatic refuelling system.
Inventor: DWARS SICCO
IPC: B67D7/34
Filed: 1993-03-17
Abstract: A system for control of automatic refueling of automotive vehicles parked alongside a fuel dispenser unit which allows for a customer to control a refueling procedure without having to exit the vehicle. The control system includes a processing unit, control operating units, operating units and a communications system which is located within the vehicle to be refueled. The communications system has the capability to start, monitor and finish the refueling procedure by transmitting and receiving data signals which concern the refueling procedure such as signals which start the refueling procedure and signals which interrupt the procedure. The data signals are received by the from the vehicle into the processing unit where the signals are processed. The processed data signals are directed to control operating units. The control operating units then direct operating units in carrying out operating functions which are necessary to automatically refuel the vehicle.
Patent ZA-941767-B (ZA)
Title: Polypeptide bombesin antagonists.
Inventor: SCHALLY ANDREW VICTOR
IPC: A61P35/00
Filed: 1994-03-14
Abstract: Pseudopeptides comprising a peptide of formula I: X-A1-A2-Trp-Ala-Val-Gly-His-Leu-psi-A9-Q wherein X is hydrogen, a single bond linking the alpha amino group of A1 to the gamma carboxyl moiety on the 3-priopionyl moiety of A2 when A2 is Glu, or a group of formula R1CO- wherein R1 is selected from the groups consisting of a) hydrogen, C1-10alkyl, phenyl or phenyl-C1-10-alkyl, p-HI-phenyl, p-HI-phenyl-C1-10-alkyl, naphthyl, naphthyl-C1-10-alkyl, indolyl, indolyl-C1-10-alkyl, pyridyl, pyridyl-C1-10-alkyl, thienyl, thienyl-C1-10-alkyl, cyclohexyl or cyclohexyl-C1-10-alkyl, where HI=F, Cl, Br, OH, CH3 or OCH3; b) N(R2)(R3)-, wherein R2 is hydrogen, C1-10alkyl, phenyl or phenyl-C1-10-alkyl, R3 is hydrogen or C1-10alkyl; c) R4O-, wherein R4 is C1-10alkyl, phenyl or phenyl-1-10-alkyl; A1 is a D- or L- amino acid residue selected from the group consisting of Phe, p-HI-Phe, pGlu, Nal, Pal, Tpi, unsubstituted Trp or Trp substituted in the benzene ring by one or more members selected from the group consisting of F, Cl, Br, NH2 or C1-3alkyl; or A1 is a peptide bond linking the acyl moiety of R1CO- to the alpha amino moiety of A2; A2 is Gln, Glu[-], Glu(Y) or His, wherein [-] is a single bond linking the gamma carboxyl group of A2 when A2 is Glu with the alpha amino group of A1 where X is a single bond, Y is -OR5 or -N(R5)(R6) wherein R5 is hydrogen, C1-3 alkyl or phenyl; R6 is hydrogen or C1-3alkyl; and R7 is hydrogen, C1-3alkyl or -NHCONH2; Leu-ypsi- is a reduced form of Leu wherein the C=O moiety of Leu is instead -CH2- such that the bond of this -CH2- moiety with the alpha amino moiety of the adjacent A9 residue is a pseudopeptide bond; A9 is Tac, MTac, or DMTac; and Q is NH2 or OQ1 where Q1 is hydrogen, C1-10alkyl, phenyl or phenyl-C1-10-alkyl; and the pharmaceutically acceptable acids or salts thereof.
Patent ZA-949149-B (ZA)
Title: Vitamin D analogs
Inventor: DORAN THOMAS I
IPC: A61P17/00
Filed: 1994-11-17
Abstract: Compounds of the formula <CHEM> wherein R is hydrogen, hydroxy, or fluorine, X is H2 or =CH2, and the 23,24-double bond is E or Z, are useful as agents for the treatment of hyperproliferative disorders of the skin such as psoriasis, as agents for the treatment of tumors such as breast cancer, as agents for the treatment of neoplastic diseases such as leukemia, and as agents for the treatment of sebaceous gland diseases such as acne and seborrheic dermatitis. They are prepared by removing the silyl protecting groups from corresponding compounds with silyl protected hydoxy groups.
Patent ZA-952222-B (ZA)
Title: Low friction cobalt based coatings for titanium
Inventor: HAJMRIE KAREL
IPC: C23C4/06
Filed: 1995-03-17
Abstract: A cobalt based coating is provided which is functional to reduce the coefficient of friction between two operatively, frictionally engaging titanium alloy surfaces.
Patent ZA-957268-B (ZA)
Title: Perhydrolysis-selective bleach activators
Inventor: BURNS MICHAEL EUGENE
IPC: C11D7/54
Filed: 1995-09-30
Abstract: Bleaching compositions, laundry and automatic dishwashing detergent compositions comprising particular neutral or anionically charged substituted bleach activators are provided. More specifically, the invention relates to compositions which provide enhanced cleaning/bleaching benefits through the selection of perhydrolysis-selective bleach activators having specific leaving groups with a conjugate acid pKa above 13 and with specific ratios of the rate of perhydrolysis to the rate of hydrolysis and the rate of perhydrolysis to the rate of diacylperoxide production. Included are preferred activator compounds and methods for washing fabrics, hard surfaces, and tableware using the activators.