baber/WOPTO huggingface dataset:
Patent WO-2020117702-A1 (WO)
Inventor: BERMINGHAM NESSAN
IPC: A61K31/7088
Filed: 2019-12-02
Abstract: The present disclosure features useful compositions and methods to treat trinucleotide repeat expansion disorders, e.g., in a subject in need thereof. In some aspects, the compositions and methods described herein are useful in the treatment of disorders associated with MSH3 activity.
Patent WO-2020117774-A1 (WO)
Title: Logic circuitry package
Inventor: CUMBIE MICHAEL W
IPC: G06F13/42
Filed: 2019-12-03
Abstract: A logic circuitry package includes an interface to communicate with a print apparatus logic circuit and at least one logic circuit including at least one heater and a temperature sensor. The at least one logic circuit is configured to receive, via the interface, a heater command to address the at least one heater. The at least one logic circuit is configured to receive, via the interface, subsequent to the heater command, a sensor command corresponding to a sensor ID to address the temperature sensor. The at least one logic circuit is configured to transmit, via the interface, a digital value in response to the sensor command. The digital value corresponds to a print material level of a print material within a reservoir.
Patent WO-2020132311-A1 (WO)
Inventor: ORAND AUSTIN J
IPC: A43B7/14
Filed: 2019-12-19
Abstract: L'invention concerne un article chaussant (10, 310, 410, 510B, 510, 610) comprenant une languette (42, 560B, 560) et un renfort de languette (590, 690) qui aide la languette (42, 560B, 560) à maintenir une forme et une position lorsque la languette (42, 560B, 560) est soumise à des forces ou à des ajustements, comme provenant d'autres éléments d'article chaussant ou d'un utilisateur. Par exemple, le renfort de languette (590, 690) peut aider la languette (42, 560B, 560) à maintenir une forme et une position lorsqu'un utilisateur insère son pied dans l'article chaussant (10, 310, 410, 510B, 510, 610) ou lorsque les quartiers médians et/ou latéraux (515) appuient vers l'intérieur sur la languette (42, 560B, 560).
Patent WO-2020142558-A1 (WO)
Inventor: OZERAN JONATHAN
IPC: G16H15/00
Filed: 2019-12-31
Abstract: A method for checking the quality of data content in a structured clinical record is disclosed. The method may include the steps of providing a data quality test that checks the content of at least a portion of the data content in the structured clinical record, applying the data quality test to the portion of the data content, and returning the results of the data quality test.
Patent WO-2020167684-A1 (WO)
Inventor: ESCUDERO OTTO FONSECA
IPC: H04W24/04
Filed: 2020-02-10
Abstract: L'invention concerne des systèmes et des procédés de surveillance des performances et d'attribution de ressources, permettant d'améliorer les performances d'un réseau de télécommunications sans fil. Un réseau de télécommunications sans fil peut être constitué de stations de base et d'autres équipements d'infrastructure, qui peuvent provenir de divers fournisseurs. Des utilisateurs peuvent générer un trafic sur le réseau sans fil et des mesures de performances, se rapportant à l'expérience d'utilisateur, peuvent être collectées à partir de stations de base individuelles. L'ensemble de mesures disponibles pour une station de base particulière peut varier selon le fournisseur. Un modèle d'apprentissage automatique est ainsi instruit à l'aide de mesures provenant de multiples stations de base et sert à estimer des valeurs pour des mesures qu'une station de base particulière ne fournit pas. Les mesures sont ensuite davantage caractérisées selon les classes de service des utilisateurs et des ressources, permettant d'améliorer les performances de stations de base, sont attribuées selon les mesures rapportées et estimées pour diverses classes de service.
Patent WO-2020185428-A1 (WO)
Title: Intégration de diodes de dérivation dans des interconnexions de modules photovoltaïques à films minces
Inventor: BUSH KEVIN ALEXANDER
IPC: H01L31/032
Filed: 2020-02-28
Abstract: L'invention concerne des modules de cellules solaires à films minces et des structures d'interconnexion de cellules à cellules en série et des procédés de fabrication. Dans un mode de réalisation, une interconnexion de cellules solaires comprend une diode de dérivation entre des cellules solaires adjacentes pour permettre le flux de courant autour d'une seule cellule solaire.
Patent WO-2020197898-A1 (WO)
Inventor: KAHLER DAVID ELLIOTT
IPC: H04N21/43
Filed: 2020-03-19
Abstract: Systems and methods are provided for synchronizing audio feeds. A system obtains a plurality of audio feeds and identifies a base feed, a first feed, a base segment, and a first segment. The system also determines a plurality of time-shifted first segments that are each temporally offset from the first segment by a unique multiple of a granularity parameter. A plurality of correlation values between the base segment and each of the plurality of time-shifted first segments are also determined, as well as a first offset value corresponding to a particular time-shifted first segment of the plurality of time-shifted first segments having the highest correlation value. The first feed and/or supplemental content of the first feed is then synchronized with the base feed by at least temporally offsetting the first feed and/or supplemental content of the first feed by a temporal offset comprising/based on the selected first offset value.
Patent WO-2020219511-A1 (WO)
Inventor: ONTUMI DENIS
IPC: A61Q11/00
Filed: 2020-04-22
Abstract: Disclosed herein are an oral care composition comprising a magnesium aluminum phyllosilicate abrasive with a high pellicle cleaning ratio (PCR) and a low relative dentin abrasivity (RDA), a method of using said oral care composition, method of its preparation, and a kit encompassing it.
Patent WO-2020232286-A1 (WO)
Inventor: BELCHER ANGELA
IPC: C12N15/74
Filed: 2020-05-14
Abstract: Provided herein, in some aspects, are methods and compositions for producing single- stranded DNA (ssDNA) having uniform length.
Patent WO-2020243148-A1 (WO)
Inventor: LOWE ADAM
IPC: G06K19/077
Filed: 2020-05-27
Abstract: Un procédé de fabrication d'une carte de transaction comprend la formation d'une ouverture dans un corps de carte de la carte de transaction; l'insertion d'un composant électronique dans l'ouverture; et la disposition d'un matériau non conducteur autour du composant électronique. Une carte de transaction comprend un composant électronique moulé.
Patent WO-2020263588-A1 (WO)
Title: Composable neural network kernels
Inventor: LIU CHAO
IPC: G06N3/04
Filed: 2020-06-11
Abstract: A technique for manipulating a generic tensor is provided. The technique includes receiving a first request to perform a first operation on a generic tensor descriptor associated with the generic tensor, responsive to the first request, performing the first operation on the generic tensor descriptor, receiving a second request to perform a second operation on generic tensor raw data associated with the generic tensor, and responsive to the second request, performing the second operation on the generic tensor raw data.
Patent WO-2021011201-A1 (WO)
Inventor: ZHU JIANGLI
IPC: G06F3/06
Filed: 2020-07-01
Abstract: In an embodiment, a system includes a plurality of memory components and a processing device that is operatively coupled with the plurality of memory components. The processing device includes host interface circuitry, middle logic, a media controller, and a media-controller restart manager that is configured to perform operations including detecting a triggering event for restarting the media controller, and responsively performing media-controller-restart operations that include suspending operation of the middle logic; determining whether the media controller is operating, and if so then suspending operation of the media controller; resetting the media controller; resuming operation of the media controller; and resuming operation of the middle logic.
Patent WO-2021025951-A1 (WO)
Inventor: IZADI SAEED
IPC: G16B15/30
Filed: 2020-07-30
Abstract: The present disclosure relates to polypeptide therapeutics, and in particular to techniques for prediction of polypeptide properties that may make for suitable polypeptide therapeutics using a model representative of electrostatics of a polypeptide. Particularly, aspects of the present disclosure are directed to ascertaining molecular multipole moments of an antibody molecule, creating a model of the antibody molecule by selecting sites within a representation of the antibody molecule, calculating a charge for each of the sites, where a combination of calculated charges for the sites approximates the molecular multipole moments of the antibody molecule, and simulating interactions of molecules in a solution. At least one molecule of the molecules in the solution is an instance of the model of the antibody molecule and the interactions are simulated based on the charges calculated for each of the sites within the representation of the antibody molecule.
Patent WO-2021030173-A1 (WO)
Inventor: TIAN ZHENG RYAN
IPC: C12N5/09
Filed: 2020-08-07
Abstract: A cell sensor and methods of using the cell sensor for differentiating types of cells. The cell sensor includes a sensing member having bioscaffolds comprising nanofibers/nanowires of titanate grown on a titanium sheet. The method includes preparing a cell sensor comprising a sensing member having bioscaffolds comprising nanofibers/nanowires of titanate grown on a titanium sheet; incubating the bioscaffolds with cells in an aqueous solution at an incubation temperature for a period of incubation time, wherein the cells in the aqueous solution include at least one of cancer cells, normal cells, stem cells, and neuron cells; and measuring electrical characteristics of the bioscaffolds to determine the types of the cells based on the measured electrical characteristics.
Patent WO-2021030335-A1 (WO)
Inventor: REED Jessica
IPC: C07D401/14
Filed: 2020-08-11
Abstract: A stereoisomerically pure NK-3 receptor antagonist is provided, including crystalline free base and salt forms thereof, as well as pharmaceutical compositions comprising the same. Also provided are methods for production of the stereoisomerically pure NK-3 receptor antagonist, as well as its use in the context of treating conditions for which antagonism of the NK-3 receptor is desired.
Patent WO-2021061337-A1 (WO)
Inventor: CHU MICHAEL S H
IPC: A61B1/018
Filed: 2020-08-27
Abstract: An endoscopic deployment device includes a body mountable on an endoscopic device, a communication interface, and a motor. The body has a movable carrier couplable to an elongated end effector device. The effector device has an end effector shaft covered by an outer sheath and an end effector extending from a distal end of the shaft. The sheath is sized and shaped for insertion through a working channel of an endoscopic shaft of the endoscopic device. The body has a carrier channel sized for the carrier to slide therein. The end effecter is actuatable between open and closed positions by sliding the carrier in the carrier channel which in turn slides the sheath over the end effector shaft to uncover/cover the end effector. Rotation of a drive shaft of the motor is sliding the carrier in the carrier channel and actuating the end effector in response to a signal.
Patent WO-2021046046-A1 (WO)
Title: Method of making a dialdeyhde
Inventor: BOONE MATTHEW ALLEN
IPC: C07C41/03
Filed: 2020-09-01
Abstract: Disclosed is a two-step process to make a dialdehyde. In the process a diepoxide is first hydrolyzed with an alcohol solvent to an intermediate which is then subjected to a double-Pinacol rearrangement to obtain a dialdehyde. The dialdehydes have utility as chemical intermediates, and particular utility in processes to make enol ether compounds which can be used in applications as plasticizers, diluents, wetting agents, coalescing aids and as intermediates in chemical processes.
Patent WO-2021050768-A1 (WO)
Title: Systems and methods for securing medical devices
Inventor: MCVANEY JESSE
IPC: A61B50/20
Filed: 2020-09-10
Abstract: A system comprises a substrate having a plurality of apertures, and a clip. The clip is removably coupled to one of the plurality of apertures. The clip has a body, a plurality of fingers, a first leg, a second leg, a first notch, and a second notch. The fingers extend from the body to collectively form at least two tube-engaging regions. The first leg is adjacent to a first end of the body and extends from the body opposite the fingers. The second leg is adjacent to a second end of the body and extends from the body opposite the fingers. The first notch is adjacent to the first end of the body and is configured to receive a first portion of the substrate. The second notch is adjacent to the second end of the body and is configured to receive a second portion of the substrate.
Patent WO-2021055499-A1 (WO)
Title: Treatment of behavioral impairment in developmental and epileptic encephalopathy
Inventor: SEBREE TERRI
IPC: A61K31/05
Filed: 2020-09-16
Abstract: The present technology relates to methods of treating behavioral problems and seizures in a subject having developmental and epileptic encephalopathy (DEE) by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein behavioral problems are treated in the subject.
Patent WO-2021061533-A1 (WO)
Inventor: PAYNE KEVIN
IPC: C08G77/16
Filed: 2020-09-18
Abstract: Hybrid moisture curable compositions comprising an acrylic copolymer, a functional silicone, a crosslinker, and a moisture cure catalyst are disclosed. The acrylic copolymer includes (i) a functional monomer selected from a silane monomer, a siloxane monomer, a hydroxy functional monomer, or a combination thereof or (ii) a reaction product of an amino silane and an acrylic polymer derived from one or more (meth)acrylates and one or more carboxylic acid anhydrides. The hybrid compositions are stable and exhibit properties typically ascribed to each individual polymer component. Methods of making and using the hybrid curable compositions are also described.
Patent WO-2021080947-A1 (WO)
Title: Electrical system for treatment of a subject
Inventor: BARBAULT ALEXANDRE
IPC: A61B6/00
Filed: 2020-10-20
Abstract: The systems and methods of this disclosure are directed to the treatment of disease states, and particularly different types of cancer, by application of low energy emission therapy. The device and method provide treatments of disease states in a patient, and particularly of cancer types, by the application to the patient of particular and disease- specific low energy high frequency radiation. The device uses a high precision frequency synthesizer to generate radio frequency radiation that is amplitude-modulated at identified tumor-specific frequencies for application to the patient during therapy.
Patent WO-2021092033-A1 (WO)
Title: Weight plate
Inventor: HENNIGER WILLIAM
IPC: A63B21/072
Filed: 2020-11-04
Abstract: A weight plate includes a first section having an annular shape with a passage extending axially through the first section and configured to receive an elongated member therethrough, and a second section having an annular shape and positioned radially outward of the first section, where the second section includes first and second outer surfaces on opposite axial sides of the weight plate with an axial thickness defined between the first and second outer surfaces. The second section has a plurality of recesses each extending axially inward from the first and second outer surfaces at least partially through the axial thickness of the second section.
Patent WO-2022098365-A1 (WO)
Title: Fire mitigation and downed conductor detection systems and methods
Inventor: SNOOK II
IPC: G01R21/06
Filed: 2020-11-06
Abstract: A transformer monitoring device has one or more voltage sensors and/or one or more current sensors integral with a housing for detecting voltage and/or current of a power cable of a transformer. The transformer monitoring device can be configured to monitor voltage data, current data, voltage imbalance, phase angle, outage detection and restoration detection, and/or transformer temperature changes, etc., and cause alerts to be Issued directly and/or by a remote central computing device if voltage levels drop, and/or if voltage imbalance occurs, along with additional alert messaging capabilities to be provided by the transformer monitoring device where utility operator personnel would find value. The transformer monitoring device further has one or more onboard, and/or external wired and/or wireless environmental and/or transformer conditions sensor(s) and/or sensor packs, including a smoke sensor, ambient temperature sensor, external transformer temperature sensor, a fire/wildfire sensor (e.g., infrared camera, etc.).
Patent WO-2021096794-A1 (WO)
Title: Method of treating an individual with a health condition with fecal microbiota transplant
Inventor: HAZAN SABINE
IPC: A61K35/74
Filed: 2020-11-09
Abstract: A method of treating an individual with a health condition comprising the steps of: a) screening the individual to determine a level of severity of the health condition; b) acquiring a fecal sample from the individual; c) processing the fecal sample; d) sequencing the fecal sample to determine the individuals microbiome; e) analyzing the sequenced fecal sample, wherein the step of analyzing the sequenced fecal sample comprises: i) comparing the individual's microbiome to the microbiome of a parent of individual; ii) comparing the individual's microbiome to the microbiome of a sibling of the individual; iii) comparing the individual's microbiome to the microbiome of another individual with same health condition; and iv) comparing the individual's microbiome with a health condition to the microbiome of the individual before they acquired the health condition; f) administering vancomycin to the individual; g) performing the fecal microbiota transplant; and h) monitoring the individual.
Patent WO-2021092587-A1 (WO)
Inventor: GENOVESE NICHOLAS J
IPC: C12N9/00
Filed: 2020-11-09
Abstract: Provided herein are methods to increase the culture density and/or thickness of a cellular biomass in a cultivation infrastructure, and to promote anchorage-independent growth of a cellular biomass in a cultivation infrastructure. The methods comprise activating a TEAD protein, for example, by increasing cellular expression of the TEAD protein or by increasing cellular expression of a fusion protein comprising a DNA-binding domain (DBD) derived from a TEAD protein and a transcriptional activation domain (TAD) in the cellular biomass. In some embodiments, the cellular biomass is harvested from the cultivation infrastructure for the formulation of cell-grown food products or ingredients, such as animal meat manufactured from cells in an  ex vivo  process or for therapeutic applications such as organ or tissue transplantation or grafting.
Patent WO-2021113414-A1 (WO)
Title: Percentile floor link qualification
Inventor: KNODE GALEN EDGAR
IPC: H04L45/02
Filed: 2020-12-02
Abstract: Devices of a control system may communicate with each other via a network. The control devices may be configured to form the network by joining the network and each attempt to attach to another device on the network. Attachment may be performed using one or more link quality thresholds. For example, the control device may measure background values and the link quality threshold may represent an N th  percentile value of the recorded background values measured at the control device. During a router optimization mode, the control devices may measure and store a communication quality metrics that may be used to assign the role of router devices and/or the role of leader device to control devices on the network.
Patent WO-2021126912-A1 (WO)
Title: Smart cementing wiper plug
Inventor: COSTA DE OLIVEIRA VICTOR
IPC: E21B33/08
Filed: 2020-12-16
Abstract: A method and system for completing cementing operations in a subterranean well with a wiper plug assembly includes delivering the wiper plug assembly into a casing, the wiper plug assembly having a wiper plug body with a circular cross section and a resilient wiper element that engages an inner diameter of the casing string. An inclination of the wiper plug assembly is measured in three dimensions with an accelerometer assembly and an azimuth of the wiper plug assembly is measured in three dimensions with a magnetometer. The inclination and the azimuth of the wiper plug assembly are delivered to a control unit in real time. An inclination of the wiper plug assembly is determined in real time. The inclination of the wiper plug assembly is delivered to an earth's surface in real time with a transmitter of the electronics package.
Patent WO-2022132165-A1 (WO)
Inventor: MENYHART ISTVAN
IPC: G06T19/00
Filed: 2020-12-18
Abstract: A computing system (100) includes a model access engine (108) configured to access a CAD model (210) comprised of multiple CAD parts. The computing system (100) also includes a model explosion engine (110) configured to construct a blocking data structure (230) for the CAD model (210) that stores a blocking state for each pair of CAD parts of the CAD model (210) as well as an explosion graph (310) for the CAD model (210). Iterative generation of the explosion graph (310) by the model explosion engine (110) includes querying the blocking data structure (230) to determine unblocked CAD parts for which to insert a node into the explosion graph (310). The model explosion engine (110) also is configured to generate an exploded view representation (410) of the CAD model (210) using the constructed explosion graph (310).
Patent WO-2021133880-A1 (WO)
Title: Planification dynamique de ressources d'antenne d'équipement utilisateur (ue)
Inventor: DING LING
IPC: H04B7/0491
Filed: 2020-12-23
Abstract: Certains aspects de la présente invention concernent des techniques de planification dynamique de ressources d'antenne d'un nœud sans fil, comme des panneaux d'antenne d'un équipement utilisateur (UE). Dans certains cas, un premier nœud (par exemple, un UE) réalise, avec deux autres nœuds ou plus, une première procédure de balayage de faisceau à travers deux ressources d'antenne ou plus du premier nœud sur deux interfaces sans fil ou plus, génère ou obtient des informations de planification sur la base des résultats de la première procédure de balayage de faisceau, les informations de planification indiquant laquelle des ressources d'antenne est prévue pour laquelle des interfaces sans fil, et communique avec les autres nœuds sur les interfaces sans fil en fonction des informations de planification.
Patent WO-2021138423-A1 (WO)
Title: Methods for genetically modifying cannabis plants, modified cannabis plants, and products therefrom
Inventor: WU LIYING
IPC: A61P43/00
Filed: 2020-12-30
Abstract: Disclosed herein are methods of inducing a modification into the genome of a  Cannabis  plant, and  Cannabis  plants having modified properties as the result of such genome modifications. Such methods may include delivering one or more polynucleotide structures capable of modifying the genome to a  Cannabis  cell in a regenerable  Cannabis  plant part, incubating the plant part and/or cell under conditions sufficient to facilitate genome modification, culturing the plant part comprising the genome modified cell to induce shoot formation, and growing the shoot to produce a genome modified  Cannabis  plant.
Patent WO-2021138540-A1 (WO)
Title: Polycyclic amides as ube2k modulators for treating cancer
Inventor: VISHNUDAS VIVEK K
IPC: C07D405/12
Filed: 2020-12-31
Abstract: Provided are compounds of Formula (I) and pharmaceutically acceptable salts and compositions thereof, which are useful for treating conditions associated with modulation of UBE2K.