baber/WOPTO huggingface dataset:
Patent RU-2638661-C2 (RU)
Inventor: KARAKHANOV EDUARD AVETISOVICH
IPC: B01D61/14
Filed: 2016-04-25
Granted: 2017-12-15
Abstract: FIELD: chemistry. 
     SUBSTANCE: invention relates to the method of the nanofiltration separation of liquid organic mixtures, in particular to the separation of large molecules of organic substances from organic solvents using membranes, and can be used in the chemical and petrochemical industries, particularly in the process of separating and recycling a homogeneous catalyst with a relative molecular weight higher 300 in the process of organic synthesis, in particular the process of hydroformylation. Nanofiltration separation of liquid organic mixtures is carried out by forcing mixtures - solutions of compounds with a relative molecular weight above 300 in organic solvents - through a flat membrane based on the 1-trimethylsilyl-1-propene copolymer (TMSP) and 1-(3,3,3-trifluoropropyldimethylsilyl)-1-propyne (TFPS). The membrane is characterized by a free volume fraction of 19-21% and insolubility in aldehydes and olefins. As solvents, aldehyde compounds are used, a version is possible, where the mixture further comprises a solvent of the olefin class. 
     EFFECT: increasing the membrane stability in aldehydes and olefins, increasing the retention coefficient of large organic molecules. 
     7 cl, 1 dwg, 4 tbl, 8 ex
Patent RU-2653504-C2 (RU)
Title: Ингибиторы тирозинкиназы брутона
Inventor: LOPEZ-TAPIA Fransisko Khaver
IPC: A61P29/00
Filed: 2014-12-10
Granted: 2018-05-10
Abstract: Изобретение относится к соединениям общей формулы I или  их фармацевтически приемлемым солям. В общей формуле I R 1  представляет собой Н или гало; R 2  представляет собой Н, гало или циано; R 3  представляет собой R 4  или R 5 ; R 4  представляет собой гало; R 5  представляет собой фенил или бензил, возможно замещенные циано, низшим алкокси или гало; 5-6-членный гетероарил, содержащий 1-2 гетероатома, выбранных из азота и серы, возможно замещенный низшим алкилом; -C(=O)R 5' ; низший алкил, замещенный циано или морфолинилом; R 5'  представляет собой 6-членный гетероциклоалкил, содержащий два гетероатома, выбранных из азота и кислорода, возможно замещенный низшим алкилом, амино, (низший алкил)амино, ди(низший алкил)амино, или низший алкокси; X представляет собой низший алкил. Соединения формулы I ингибируют Btk (тирозинкиназу Брутона). Соединения формулы I полезны для модулирования активности Btk и лечения заболеваний, ассоциированных с излишней активностью Btk. Соединения полезны для лечения онкологических, аутоиммунных и воспалительных заболеваний, вызванных нарушенной активацией В-клеток. Изобретение также относится к фармацевтическим композициям, содержащим соединения формулы I и, по меньшей мере, один носитель, разбавитель или эксципиент. 10 н. и 14 з.п. ф-лы, 2 табл., 21 пр. 
     .
Patent RU-2670909-C2 (RU)
Title: Thread context restoration in multi-threading computer system
Inventor: GREJNER Den
IPC: G06F9/46
Filed: 2015-03-16
Granted: 2018-10-25
Abstract: FIELD: computing; counting.SUBSTANCE: invention relates to a computer system and a computer-implemented method for thread context restoration in a configuration. System comprises a configuration comprising a core configurable between a single thread (ST) mode and a multithreading (MT) mode, the ST mode addressing a primary thread and the MT mode addressing the primary thread and one or more secondary threads on shared resources of the core, and a multithreading facility configured to control utilisation of the configuration to perform a method comprising disabling the one or more secondary threads , based on switching from the MT mode to the ST mode in response to a reset or disabling the configuration, querying, during execution in ST mode, a last-specified maximum MT level to determine a last-specified program-specified maximum thread ID of the configuration, and obtaining the thread context of the one or more secondary threads by executing a set MT instruction to resume the MT mode and accessing the thread context of the one or more secondary threads based on being in the resumed MT mode.EFFECT: technical result is to provide support for multi-thread data processing.15 cl, 17 dwg, 1 tbl
Patent RU-2652533-C2 (RU)
Title: Способ изготовления компонента
Inventor: GAJGER Volfram
IPC: B81B3/00
Filed: 2015-02-11
Granted: 2018-04-26
Abstract: Использование: для создания микромеханического компонента. Сущность изобретения заключается в том, что способ изготовления микроэлектромеханического компонента включает этап изготовления композита первого слоя, содержащего структурированный слой, который является электропроводящим по меньшей мере на первом участке, и канавку, заполненную изолирующим материалом, которая проходит в наружном направлении от первой поверхности структурированного слоя и размещена на первом участке структурированного слоя, причем первая поверхность структурированного слоя  обращена к первой поверхности композита первого слоя, этап изготовления композита второго слоя, имеющего первое углубление на первой поверхности  композита  второго слоя, этап соединения композита первого слоя с композитом второго слоя с примыканием первой поверхности композита первого слоя к первой поверхности композита второго слоя по меньшей мере на некоторых участках и размещением заполненной канавки в пределах бокового положения первого углубления, после соединения композита (10) первого слоя с композитом (20) второго слоя толщину композита (10) первого слоя уменьшают от второй поверхности (112) композита (10) первого слоя до глубины заполненной канавки (15), причем вторую поверхность (112) композита (10) первого слоя располагают напротив первой поверхности (110) композита (10) первого слоя, и этап изготовления активной структуры (17) компонента (1) в структурированном слое (11), причем активная структура (17) размещена в пределах бокового положения первого углубления (210) и содержит два вторых участка (115) структурированного слоя, которые размещены на первом участке структурированного слоя, жестко физически соединены друг с другом и электрически изолированы друг от друга посредством заполненных канавок; до соединения композита первого слоя с композитом второго слоя заполненная канавка в композите первого слоя проходит на глубину, которая меньше толщины композита первого слоя; композит первого слоя дополнительно содержит вспомогательный слой, примыкающий ко второй поверхности структурированного слоя, причем вторая поверхность структурированного слоя расположена напротив первой поверхности структурированного слоя, и заполненная канавка проходит на вторую поверхность структурированного слоя. Технический результат - обеспечение возможности создания микромеханического компонента с двумя отдельными частями, которые жестко механически соединены друг с другом, но полностью изолированы друг от друга. 8 з.п. ф-лы, 12 ил.
Patent RU-2694368-C2 (RU)
Title: Solid pharmaceutical compositions containing biopterin derivatives, and methods of using such compositions
Inventor: SCHEURER PETER
IPC: A61K9/08
Filed: 2015-03-30
Granted: 2019-07-12
Abstract: FIELD: medicine; pharmaceuticals.SUBSTANCE: present invention relates to solid pharmaceutical compositions containing biopterin derivatives, as well as methods for preparing such solid pharmaceutical compositions. Composition according to invention contains 4-amino-5,6,7,8-tetrahydro-L-biopinterin (I) and/or 4-amino-7,8-dihydro-L-biopinterin (II) and two different phosphate salts of sodium NaHPO⋅2HO and NaHPO⋅2HO. Molar ratio as NaHPO⋅2HO and NaHPO⋅2HO to compound (I) or compound (II) ranges from 0.02 to 0.5. Composition can additionally contain auxiliary substance NaCl. Also described is a method for preparing a solid pharmaceutical composition in the form of a lyophilizate and using said composition for treating traumatic brain injury and secondary cerebral injury. Also described is a method of producing an injection solution.EFFECT: compositions according to the invention provide no oxidation of biopsyderin derivatives and are stable during storage.42 cl, 3 dwg, 6 tbl, 3 ex
Patent RU-2737928-C2 (RU)
Inventor: KITANI NAOFUMI
IPC: B60C11/03
Filed: 2017-05-25
Granted: 2020-12-09
Abstract: FIELD: automotive industry.SUBSTANCE: tire 1 includes tread 2 equipped with first main groove 3 and second main groove 4, each of which passes in zigzag manner and area 10 of contact with soil, determined between them. Area 10 of contact with soil is equipped with lengthwise lamella 15, passing in zigzag manner in longitudinal direction of tire, first transverse grooves 16 and second transverse grooves 17. Area 10 of contact with soil includes first units 21 separated by lengthwise lamella 15 and first transverse grooves 16, and second blocks 22 separated by lengthwise lamella 15 and second transverse grooves 17. Each of first blocks 21 and second blocks 22 is equipped with at least three transversal lamels 25, passing along the whole width of each of first blocks 21 and second blocks 22.EFFECT: technical result is improvement of performance characteristics on ice-covered road surface.9 cl, 6 dwg, 1 tbl
Patent RU-2693396-C2 (RU)
Title: Water scooping apparatus for forestfire suppressant in non-amphibious airtankers
Inventor: BENEDIK JACK
IPC: B64D1/22
Filed: 2016-01-12
Granted: 2019-07-02
Abstract: FIELD: machine building. 
     SUBSTANCE: invention relates to water intake device for aircraft. Air intake device (2) for aircraft includes extension pipe (5), one end of which is hingedly connected to aircraft (1); feed pipe (4) hydraulically connecting said end of extending pipe (5) with water reservoir (10), float (7) connected to the other end of sliding pipe (5) and having inlet hole for water intake. Inlet hole is hydraulically connected with extending pipe (5). Water intake device (2) is made with possibility of transition from retracted position, in which extension pipe (5) is substantially retracted, into working position, in which extending pipe (5) extends downward from aircraft (1) at some angle. 
     EFFECT: invention allows collecting the largest volume of water during a very short period of time with minimum forces acting on the aircraft. 
     14 cl, 6 dwg
Patent RU-2731673-C2 (RU)
Inventor: GROENEVELD STEVEN CRAIG
IPC: C12C11/11
Filed: 2016-05-16
Granted: 2020-09-07
Abstract: FIELD: brewing industry. 
     SUBSTANCE: invention relates to extraction of waste beer. In this method yeast involved in beer is extracted from fermentation stage and separated from beer to produce extracted beer, which is then passed through a unit of ultraviolet photosterilization under certain treatment conditions to produce sterilized extracted beer, which is repeatedly introduced into the fermentation step. 
     EFFECT: invention allows to prevent microbial contamination of beer, maintain content of alcohol in re-treated beer, as well as its taste characteristics and taste stability. 
     10 cl, 1 dwg, 1 ex
Patent RU-2748992-C2 (RU)
Title: Delivery systems for controlled drug release
Inventor: KRATTS Feliks
IPC: C07H19/10
Filed: 2016-06-17
Granted: 2021-06-02
Abstract: FIELD: biochemistry. 
     SUBSTANCE: invention relates to the compound of Formula (I) 
     
       
     
     or a pharmaceutically acceptable salt thereof, diastereomer or stereoisomer  wherein the Agent is selected from the group consisting of a cytostatic agent, a cytotoxic agent and a derivative of any of the above, the Spacer is absent or is selected from the group consisting of   and   , n is 0, X is unsubstituted 6-membered aryl, Y is absent or is selected from the group consisting of unsubstituted C 1 -C6 alkylene, -NH-C(O)-, -C(O)-NH-, C(O)-O- and -O-C(O)-, R 1  is absent or is unsubstituted  C 1 -C 18  alkylene or R 1  has the following formula: 
     
       
     
     R 2  is selected from the group consisting of -H and unsubstituted C 1 -C 12  alkyl, each of Z 1 , Z 2 , Z 3  and Z 4  independently represents -H, halogen or -NO 2 , PBG represents an unsubstituted maleimide group, while when the Spacer is absent, the Agent is bound to nitrogen adjacent to the Spacer through a double bond, and wherein at least one of Z 1 , Z 2 , Z 3  and Z 4  is not Н. Also proposed is a pharmaceutical composition, a method for treating a malignant neoplasm and the use of a compound or composition in the manufacture of a medicament.  
     EFFECT: proposed compounds can be used for efficient and controlled drug delivery and release.  
     46 cl, 8 dwg, 1 tbl, 13 ex
Patent RU-2697811-C2 (RU)
Title: Simulator of radio navigation signals
Inventor: GREBENNIKOV ANDREJ VLADIMIROVICH
IPC: G01S7/40
Filed: 2018-01-22
Granted: 2019-08-20
Abstract: FIELD: physics.SUBSTANCE: invention relates to radio navigation and can be used to generate radio signals similar to GLONASS and GPS global satellite radio navigation systems navigation satellites. Said result is achieved due to that simulator of navigation signals comprises digital signal generation unit, frequency converter up, attenuator, wherein said digital signal generation unit consists of an exchange interface unit, a pseudorandom sequence signal generation unit, a signal synthesis unit, a filter and an additional filter. Listed facilities included in the simulator are made and interconnected in a certain way.EFFECT: technical result is simple simulator and improved characteristics of output signal similar to real from satellite radio navigation systems GLONASS and GPS.1 cl, 2 dwg
Patent RU-2690266-C2 (RU)
Title: Улучшение формуемости деформируемых сплавов медь-никель-олово
Inventor: WETZEL JOHN F
IPC: C22F1/08
Filed: 2014-03-11
Granted: 2019-05-31
Abstract: Изобретение относится к спинодальным сплавам медь-никель-олово. Сплав включает в себя от примерно 14,5 до примерно 15,5 мас.% никеля, от примерно 7,5 мас.% до примерно 8,5 мас.% олова и остаток - медь. Сплав медь-никель-олово подвергают холодной механической обработке давлением до достижения степени холодной деформации от 5% до 15%. Затем сплав подвергают термической обработке при повышенных температурах от примерно 450°F до примерно 550°F в течение периода времени от примерно 3 часов до примерно 5 часов. Затем сплав последовательно снова подвергают холодной механической обработке давлением до достижения степени холодной деформации от 4% до 12%. Затем сплав дополнительно нагревают до повышенной температуры от примерно 700°F до примерно 850°F в течение периода времени от примерно 3 минут до примерно 12 минут для снятия напряжения. Получающийся в результате сплав обладает комбинацией хорошего коэффициента формуемости и хорошего предела текучести. 16 з.п. ф-лы, 1 пр., 4 табл., 4 ил.
Patent RU-2674976-C2 (RU)
Inventor: Nyushko Kirill Mikhajlovich
IPC: A61B17/00
Filed: 2018-03-28
Granted: 2018-12-13
Abstract: FIELD: medicine. 
     SUBSTANCE: invention relates to medicine, namely to oncology. Remove the prostate gland with seminal vesicles, pelvic tissue with lymph nodes, form vesicourethral anastomosis. Parietal peritoneum is pulled out and the parietal leaf is dissected using a monopolar coagulator along the transition fold and the distal parts of the lateral canals. Cavity of a small pelvis on the right and on the left is drained. Wound is sutured in layers. 
     EFFECT: invention may be applicable for the prevention of lymphorrhea and lymphocyst in patients with prostate cancer after surgical treatment. 
     1 cl, 5 dwg, 1 tbl, 1 ex
Patent RU-2740163-C2 (RU)
Inventor: TAKAKhASI Khiroo
IPC: G06F13/42
Filed: 2017-05-02
Granted: 2021-01-12
Abstract: FIELD: communication equipment. 
     SUBSTANCE: present invention relates to a communication device, a communication method and a communication system. Communication device comprises: transmission/reception unit, which transmits/receives signal to/from another device; confirmation signal detection unit, which detects one of the acknowledgment signal and the non-acknowledgment signal, wherein the acknowledgment signal and the non-acknowledgment signal are transmitted from the other device, which received signal transmitted from transmission/reception unit; and conflict prevention unit, which indicates transmission/reception unit to transmit interrupt signal to indicate interruption of communication after ignoring a given number of bits after a non-acknowledgment signal when the unit detects a confirmation signal of a non-acknowledgment signal. 
     EFFECT: technical result is more reliable communication. 
     19 cl, 7 dwg
Patent RU-2741425-C2 (RU)
Title: Каталитическая композиция, содержащая цеолит типа con и цеолит типа zsm-5, получение и способ применения указанной композиции
Inventor: ZUIDEMA ERIK
IPC: B01J29/80
Filed: 2017-07-10
Granted: 2021-01-26
Abstract: Изобретение относится к каталитической композиции, способу ее получения и способу трансалкилирования сырья, содержащего алкилароматические углеводороды, с применением каталитической композиции. Каталитическая композиция для трансалкилирования сырья, содержащего алкилароматические углеводороды, содержит (a) носитель, содержащий (i) цеолит типа CON в количестве от 5 до 95 мас. % в пересчете на общую массу носителя, (ii) цеолит типа ZSM-5 в количестве от 5 до 95 мас. % в пересчете на общую массу носителя; и (iii) неорганическое связующее вещество, выбранное из группы, состоящей из оксида алюминия, гамма-оксида алюминия, диоксида кремния, диоксида кремния-оксида алюминия, бентонита, каолина, диоксида титана, диоксида циркония, диоксида церия, оксида галлия, клиноптилолита, монтмориллонита и любой их смеси, в количестве от 10 до 40 мас. % в пересчете на общую массу носителя; и (b) от 0,1 до 10 мас. % одного или более металлов, выбранных из группы, состоящей из вольфрама, ванадия, молибдена, рения, никеля, кобальта, хрома, марганца, платины и палладия. Способ получения каталитической композиции включает следующие стадии: (а) смешивание цеолита типа CON, цеолита типа ZSM-5 и неорганического связующего вещества и экструдирование полученной смеси, (b) необязательно подвергание экструдатов, полученных на стадии (а), термической обработке, (с) пропитка экструдатов раствором, содержащим один или более металлов, выбранных из группы, состоящей из вольфрама, ванадия, молибдена, рения, никеля, кобальта, хрома, марганца, платины и палладия, и (d) необязательно подвергание пропитанных экструдатов, полученных на стадии (с), термической обработке. Технический результат заключается в обеспечении более высокой конверсии метилэтилбензола в трансалкилировании и получение продукта, имеющего низкое отношение этилбензола к общему количеству ароматических соединений, имеющих 8 атомов углерода, при относительно высоком выходе ксилола и относительно высокой полной конверсии. 3 н. и 7 з.п. ф-лы, 2 табл., 1 пр.
Patent RU-2762986-C2 (RU)
Title: Quality control of drug of plant origin based on mechanism
Inventor: CHENG YUNGCHI
IPC: A61K36/539
Filed: 2017-06-21
Granted: 2021-12-24
Abstract: FIELD: medicine. 
     SUBSTANCE: group of inventions relates to methods for assessing the quality of a batch of a composition based on medicinal herbs. A method for assessing the quality and potential in vivo activity of a test batch of a composition based on medicinal herbs includes analysis of a test batch of a composition based on medicinal herbs by one or several biological analysis methods selected from: (a) analysis of a response associated with signal transduction activity, which includes measurement of a response associated with signal transduction activity against one or more signaling pathways selected from a group consisting of TNFa-NFkB, TLR2-NFkB, TLR4-NFkB, IL6-stat3, IFNg-stat1/1, IFNa-stat1/2, DEX-GR, COX-2, iNOS, NRF2, TGFb-Smad2/3, TPA-AP1, CREB, wnt3a-Lef/b-cat, VD3-VDR, ER-alpha, ER-beta, DHT-AR and aldosterone-MR; and (b) gene expression analysis, where gene expression analysis includes quantification of one or several protein coding genes selected from a group consisting of ICAM, IRF5, AKR1C1, HO1, GCLC, GCLM, Axin2, GDF15, IGFBP3, OKL38, PIM1, SERTAD, SOS1, BHMT2, CPT1A, SLC7A11, CD24, EMP2 and KRT23; and then a comparison of the results of the biological analysis of the test batch with the results obtained for a known batch of a composition based on medicinal herbs, which has a known level of in vivo activity; where, if the results obtained for the test batch have a correlation coefficient from 0.95 to 1.0 with the results obtained for a known batch, the test batch is determined as having quality sufficiently corresponding to the quality of the known batch, and potential in vivo activity (options).  
     EFFECT: above-described methods, including biological analyses, such as analysis of the response associated with the signal transduction activity, or gene expression analysis, effectively predict the potential in vivo activity of the tested batch of a composition based on medicinal herbs better than LC-MS chemical analysis. 
     8 cl, 3 dwg, 2 tbl, 3 ex
Patent RU-2750470-C2 (RU)
Title: Device containing two supports
Inventor: THELLIER HERVE
IPC: C03B40/00
Filed: 2018-02-22
Granted: 2021-06-28
Abstract: FIELD: glass production. 
     SUBSTANCE: device for supporting a glass sheet or a stack of glass sheets, called glass, in the contact band between the edge and up to 200 mm from the edge of the glass, without contact with the glass beyond 200 mm from the edge of the glass, contains the first support and the second support. Each of the supports contains a frame and supporting means for supporting the glass, connected to the frame. The support means of each support contain a glass support surface containing a fibrous material capable of contacting the glass in the contact band at a temperature between 400°C and 600°C. The two supports are capable of moving in a transmitting vertical relative motion, allowing the support surface of one of them to pass over or under the support surface of the other one to transmit glass from one support to the other. The support means of the first support contain a passage that allows the lever connected to the second support to pass during the transmitting vertical relative movement. The first support supporting the glass can be placed in a chamber with a special temperature, after which the second support accepts the glass to remove it from the chamber and move it to a cooler area. Then the first support can receive the next glass.  
     EFFECT: invention is particularly suitable for processing glass sheets moving one after another. 
     23 cl, 8 dwg
Patent RU-2756641-C2 (RU)
Title: Method for storing information using dna and information storage device
Inventor: Das Hillol
IPC: B82B3/00
Filed: 2019-10-29
Granted: 2021-10-04
Abstract: FIELD: biotechnology.SUBSTANCE: group of inventions relates to biotechnology, in particular nano-technologies for storing information using DNA. Information is placed sequentially on single-stranded DNA by connecting closed primers complementary to this DNA to it. Each closed primer contains a deoxynucleotide chain terminated at the 3' end by dideoxynucleotide. Closed primers are placed on single-stranded DNA with gaps, on which no nucleotides are attached to single-stranded DNA. The length of primers encodes a digit of stored digital information. Zero is represented by a closed primer with a length ofNnucleotides, one is represented by a closed primer with a length ofKnucleotides. An interval ofMnucleotides is made between two consecutive closed primers connected to single-stranded DNA.N> 0,K> 0, K ≠ N,M> 0.EFFECT: solutions are intended for archiving and long-term storage of any types of existing information.18 cl, 5 dwg, 6 ex
Patent UA-53141-C2 (UA)
Title: Method for fast moving contacts of a switching unit and a device for the realization of the method
Inventor: LOZA VIKTOR MYKHAILOVYCH
IPC: H01H5/18
Filed: 2002-03-21
Abstract: The proposed method for fast moving contacts of a switching unit consists in changing the position of the spring by applying force to the spring on both the sides. The proposed device for the realization of the method contains a casing, a movable contact, a fixed contact, an actuator for the movable contact, a leaf spring with locks, and pushers arranged on both the sides of the spring. The spring is coupled with the movable contact via a link made of insulating material. The pushers are coupled with the actuator for the movable contact.