baber/WOPTO huggingface dataset:
Patent EP-3538554-A1 (EP)
Inventor: GROMADA JESPER
IPC: A61K39/395
Filed: 2017-11-08
Abstract: The present invention provides antibodies and antigen-binding fragments of antibodies that bind to leptin receptor (LEPR), and methods of using the same. According to certain embodiments, the invention includes antibodies and antigen-binding fragments of antibodies that bind LEPR and antagonize LEPR signaling. In certain embodiments, the invention includes antibodies and antigen-binding fragments of antibodies that bind LEPR in the presence or absence of leptin. In other embodiments, the invention includes antibodies and antigen-binding fragments of antibodies that exhibit partial agonism of LEPR signaling. The antibodies and antigen-binding fragments of the present invention are useful for the treatment of various conditions, including but not limited to congestive heart failure cachexia, pulmonary cachexia and cancer cachexia, autoimmune disorders such as inflammatory bowel disease, lupus erythematosus, multiple sclerosis, psoriasis, cardiovascular diseases, elevated blood pressure, neurodegenerative disorders, depression, cancer such as hepatocellular carcinoma, melanoma, breast cancer, and other diseases and disorders associated with or caused by elevated leptin signaling.
Patent EP-3555657-A1 (EP)
Inventor: DÖRING BJÖRN
IPC: H01Q15/14
Filed: 2017-11-29
Abstract: L'invention concerne un procédé radar à ouverture synthétique destiné à la télédétection de la surface terrestre par le biais d'un dispositif radar (1) qui se déplace dans une direction azimutale (x) au-dessus de la surface terrestre. Le dispositif radar (1) comporte un dispositif d'émission destiné à émettre des impulsions radar et un dispositif de réception destiné à recevoir des échos radar. Dans un mode de fonctionnement prédéfini du dispositif radar (1), des impulsions radar sont émises par le dispositif d'émission et des échos radar sont reçus par le dispositif de réception. Des cellules de résolution sont définies pour le mode de fonctionnement prédéfini, lesquelles représentent des segments de surface aux dimensions identiques sur la surface terrestre et représentent la résolution dans l'espace du mode de fonctionnement prédéfini. De plus, dans le mode de fonctionnement prédéfini, des données brutes de SAR sont acquises par la réception des échos radar qui émanent d'un ou plusieurs arrangements de rétrodiffusion (2) installés sur la surface terrestre et respectivement composés de plusieurs éléments de rétrodiffusion (3). les éléments de rétrodiffusion (3) de chaque arrangement de rétrodiffusion (2) sont positionnés les uns par rapport aux autres de telle sorte que tous les éléments de rétrodiffusion (3) de l'arrangement de rétrodiffusion (2) correspondant se trouvent à l'intérieur d'une cellule de résolution, et chaque arrangement de rétrodiffusion (2) possède un ou plusieurs paramètres de rétrodiffusion connus à l'avance. Les données brutes de SAR sont soumises à un traitement de signal, lequel comporte la génération d'images radar SAR de la surface terrestre à partir des données brutes de SAR et est dépendant du ou des paramètres de rétrodiffusion connus à l'avance.
Patent EP-3552406-A1 (EP)
Inventor: KENT LIONEL WILLIAM JOHN
IPC: H04B11/00
Filed: 2017-11-27
Abstract: An electroacoustic transducer, comprising a piezoelectric part comprising a piezoelectric material having a first acoustical impedance and an acoustical thickness, a substrate part comprising a material having a second acoustical impedance, and an intermediate part comprising a material having a third acoustical impedance and at least partially sandwiched between the piezoelectric part and the substrate part for acoustical communication therewith. The first acoustical impedance and the second acoustical impedance each has a respective value within a range of values for which the value of third acoustical impedance: is an upper limit if said acoustical thickness is less than 0.4Λ,or is a lower limit if said acoustical thickness is greater than 0.4Λ where Λ is an acoustical wavelength in the material of the piezoelectric part.
Patent EP-3694771-A1 (EP)
Title: Wheel-well closure system for a motor vehicle, and motor vehicle comprising such a system
Inventor: BALLARIN PAOLO
IPC: B62D35/00
Filed: 2017-10-13
Abstract: The invention concerns a wheel-well closure system (10) for a motor vehicle (1), having a wheel-arch (2) delimiting a wheel-well (3) and a wheel (4) mounted in the wheel-well (3), the system (10) comprising: a support structure (20) connected to the wheel-arch (2); and a cover connected to the support structure (20) and covering the wheel-well (3); wherein the cover is made of a flexible material and is secured to the wheel arch (2); wherein the system (10) comprises a continuous annular part secured to the wheel (4) facing the cover and rotating with the wheel (4) about a horizontal axis (X4); and wherein the support structure (20) comprises an arm (22) extending radially in front of the continuous annular part and against the cover, a steering movement of the wheel (4) about a vertical axis (Y4) causing the continuous annular to push the support structure (20) and stretch the cover outside the wheel-well (3).
Patent EP-3446667-A1 (EP)
Inventor: MUKAI HIROTOMO
IPC: A61F13/494
Filed: 2017-06-05
Abstract: An absorbent article (1) includes: an absorbent main body (10) including an absorbent core (40) ; and a pair of leak-proof walls (20) . The pair of leak-proof walls (20) are provided on respective widthwise side portions of the absorbent main body (10) . Each of the leak-proof walls (20) is capable of standing on a skin side in the thickness direction, and includes a skin-side portion (23) and a non-skin-side portion (24). The absorbent core (40) includes a low-basis-weight portion (43) in a widthwise central portion, and the low-basis-weight portion (43) is a portion in which a basis weight of the absorbent core (40) is smaller than the basis weight in a surrounding of the portion. A joined part (27) is formed by joining at least partially a surface of the skin-side portion (23) and a surface of the non-skin-side portion (24), the surfaces facing to each other. The joined part (27) is provided inside a distal end of the leak-proof wall (20) and outside the low-basis-weight portion (43) in the width direction. A part of the joined part (27) and a part of the low-basis-weight portion (43) at least overlapping in the longitudinal direction.
Patent EP-3477741-A1 (EP)
Inventor: YAMAMOTO SHO
IPC: H01M50/497
Filed: 2017-06-21
Abstract: A LDH containing functional layer and a composite material including the same are provided, wherein the functional layer and the composite material have not only high ionic conductivity but also high alkaline resistance. The functional layer includes a layered double hydroxide and has high hydroxide ion conductivity. The layered double hydroxide does not undergo a change in the surface microstructure and the crystalline structure when immersed in 5 mol/L of an aqueous potassium hydroxide solution containing zinc oxide in a concentration of 0.4 mol/L at 70 °C for three weeks.
Patent EP-3472719-A1 (EP)
Inventor: MCNEELY MARK
IPC: G06F15/16
Filed: 2017-06-21
Abstract: La présente invention vise à permettre une authentification initiale plus sûre et continue d'une tunnellisation de réseau privé virtuel (VPN pour Virtual Private Network). Le dispositif de la présente invention contient son propre microprocesseur et son propre système d'exploitation qui est relié au système hôte par le biais d'un bus série universel (USB pour Universal Serial Bus) ou d'un autre mode de couplage. La présente invention implique l'exécution et le stockage du logiciel de réseau VPN, des certificats, des justificatifs et des capteurs sur le dispositif, ce qui permet une plus grande sécurité et une plus grande facilité de gestion par opposition à l'exécution du réseau VPN sur le système hôte. Le dispositif authentifie de façon continue la présence de l'utilisateur par biométrie ou la présence d'un second dispositif, y compris un téléphone intelligent, une montre connectée, un anneau NFC ou un dispositif personnalisé ayant un microprocesseur, par le biais de codes de réponse rapide (QR pour Quick Response), une communication en champ proche (NFC pour Near Field Communication) ou une authentification de proximité à faible énergie (LE pour Low Energy) par Bluetooth pour activer ou désactiver le tunnel de réseau VPN.
Patent EP-3474869-A1 (EP)
Title: Compositions dérivées de tissu humain et leurs utilisations
Inventor: SINCLAIR STEVEN MICHAEL
IPC: A61K31/722
Filed: 2017-06-23
Abstract: La présente invention concerne des compositions comprenant une matrice chorionique non homogénéisée, une matrice amniotique homogénéisée et une matrice UC (UC) homogénéisée, la matrice chorionique non homogénéisée comprenant des cellules viables. L'invention concerne des procédés de fabrication des compositions de l'invention, comprenant la préparation d'une matrice chorionique non homogénéisée, la préparation d'une matrice amniotique homogénéisée, la préparation d'une matrice UC homogénéisée, et la combinaison de la matrice chorionique non homogénéisée, la matrice chorionique non homogénéisée et la matrice UC homogénéisée. L'invention concerne des procédés de traitement d'une lésion tissulaire ou d'une douleur chronique, comprenant l'administration de l'une quelconque des compositions de l'invention à une zone d'un sujet comprenant une lésion tissulaire.
Patent EP-3499955-A1 (EP)
Title: Communication device, communication method and recording medium
Inventor: SHIMEZAWA KAZUYUKI
IPC: H04W28/06
Filed: 2017-07-07
Abstract: [Object] To provide a mechanism that enables flexible design in relation to communication timing. 
     [Solution] A communication apparatus including: a communication control unit that controls communication with another communication apparatus, which is a communication counterpart, through frequency division duplexing (FDD). The communication control unit transmits a second sub frame that is transmitted from the communication apparatus to the other communication apparatus and corresponds to a first sub frame after the first sub frame that is transmitted from the other communication apparatus to the communication apparatus.
Patent EP-3505535-A1 (EP)
Inventor: LI BAIYONG
IPC: A61K39/395
Filed: 2017-08-22
Abstract: An anti-PDl (programmed cell death 1) monoclonal antibody or an antigen-binding fragment thereof, a pharmaceutical composition thereof and use thereof. The heavy chain variable region of the monoclonal antibody comprises CDRs (complementary determining region) of amino acid sequences as shown in SEQ ID NO:9-11; and/or the light chain variable region of the monoclonal antibody comprises CDRs of amino acid sequences as shown in SEQ ID NO: 12-14. The monoclonal antibody can bind to PD1 specifically, relieve immunosuppression of PD1 on an organism specifically and activate T lymphocytes.
Patent EP-3506573-A1 (EP)
Inventor: WEN TAICHUAN
IPC: H04L47/22
Filed: 2017-08-23
Abstract: Provided are a traffic control method, system, a packet switching apparatus, and a user equipment, wherein the method includes: receiving configuration information, wherein a committed information rate of a multicast service and/or a unicast service is carried in the configuration information; and setting an egress information rate of the multicast service and/or the unicast service at a packet switching apparatus according to the committed information rate. By employing the above technical solution, a problem that the service traffic is difficult to guarantee in existing technology can be solved, and a user requirement for successful unicast service or multicast service can be achieved.
Patent EP-3494735-A1 (EP)
Title: Système et procédé de réveil sécurisé et rapide d'une station
Inventor: YANG YUNSONG
IPC: H04L29/06
Filed: 2017-08-15
Abstract: Un procédé de réveil d'un module de communication radio (RCM, "radio communication module") d'une station avec un récepteur de réveil comprend la réception d'un signal de réveil avec le récepteur de réveil, le réveil du RCM à partir d'un mode de sommeil, la transmission d'une seconde trame si une première trame est reçue dans un temps spécifié après le réveil du RCM et si une intégrité de la première trame est vérifiée avec succès, et le placement du RCM et du récepteur de réveil en un mode sommeil et en un mode actif, respectivement, si la première trame n'est pas reçue dans le temps spécifié après le réveil du RCM, ou si la première trame est reçue dans le temps spécifié après le réveil du RCM mais que l'intégrité de la première trame n'est pas vérifiée avec succès.
Patent EP-3489105-A1 (EP)
Inventor: CHEN DAWEI
IPC: B61D1/02
Filed: 2017-08-26
Abstract: Provided are a railway vehicle carriage structure and a railway vehicle. Doors (9) enabling passengers to board and alight are provided on two sides of a vehicle body of at least one end part of a carriage (1, 2), a region directly between the doors is a vestibule (12), and the space of the vestibule (12) is substantially circular. This type of carriage structure enlarges the passing space in the vestibule (12) for people, can effectively relieve the state of overcrowding when a large number of people are boarding and alighting, and increases the comfort of passengers of railway vehicles
Patent EP-3508533-A1 (EP)
Inventor: FUJISAWA TOYOHIKO
IPC: C08L83/05
Filed: 2017-08-24
Abstract: [Problem] To provide a curable organopolysiloxane composition, etc. which has a particularly excellent effect of improving initial adhesiveness in small amounts and a thin layer with respect to various base materials, in addition to being able to achieve particularly excellent adhesive durability and high adhesive strength after curing. 
     [Resolution means] A curable organopolysiloxane composition, containing: 
(A) an organopolysiloxane having at least two alkenyl groups per one molecule; (B) a trialcoxysilyl containing siloxane having one silicon atom-bonded hydrogen atom and at least one trialcoxysilyl group per one molecule; (C) a chain or cyclic organopolysiloxane having at least two silicon atom-bonded hydrogen atoms per one molecule; (D) a chain organopolysiloxane having at least three silicon atom-bonded hydrogen atoms per one molecule; (E) a catalyst for a hydrosilylation reaction; (F) a catalyst for a condensation reaction; and (G) an adhesion promoter.
Patent EP-3486892-A1 (EP)
Inventor: WAGA IWAO
IPC: G09F13/42
Filed: 2017-04-03
Abstract: The present invention provides a method of setting light emission control of each light emission tool in an area more easily. The method of setting light emission control of each light emission tool in an area of the present invention includes: a light emitting step of transmitting a freely-selected ID signal (S n ) to a plurality of light emission tools that are randomly disposed in an area and emit light in response to receipt of corresponding ID signals to cause a light emission tool (E n ) that has received the ID signal (S n ) to emit light; an imaging step of acquiring a light emission image (E n ) of the area after the ID signal (S n ) has been transmitted; a determining step of determining a position of the light emission tool (E n ) that emitted light in response to receipt of the ID signal (S n ) in the area based on the light emission image (E n ); and a storing step of storing the position of the light emission tool (E n ) in the area and the corresponding ID signal (S n ) in association with each other.
Patent EP-3537158-A1 (EP)
Inventor: KARAMZIN SERGEY SERGEEVICH
IPC: G01N33/86
Filed: 2017-11-12
Abstract: The device for monitoring the spatial and temporal dynamics of thrombin that includes a temperature-controlled sealed chamber with a transparent window and a light trap, said chamber being filled with a fluid medium and designed to be capable of accommodating a cuvette containing a test sample of blood plasma, and into which a coagulation activating insert is placed, the latter having a substance which initiates the coagulation process applied to the butt end thereof, at least one means of illumination of the sample designed to be capable of receiving the light scattering signal from the sample and at least one first means of irradiation designed to be capable of exciting the fluorescence signal of a special marker that forms in the sample during the cleavage of a fluorogenic substrate previously added to the sample by one of the proteolytic enzymes of the coagulation system, a means of optical photo/ video registration of light scattering /irradiation from the sample, a means for adjustment of pressure in the temperature-controlled sealed chamber designed to be capable of maintaining a pressure inside the chamber exceeding the atmospheric one, at that the device includes at least one second means of irradiation of the sample designed to be capable of exciting a fluorescence signal of the said marker, at least one first means of irradiation that provides irradiation of the sample in a direction perpendicular to the cuvette plane, and at least one second means of irradiation that provides irradiation of the sample at an angle to the cuvette plane.
Patent EP-3564306-A1 (EP)
Inventor: HIURA Takahiro
IPC: C08L29/04
Filed: 2017-12-22
Abstract: A water-soluble film includes: a polyvinyl alcohol resin (A); and a plasticizer (B), wherein the plasticizer (B) contains a polyhydric alcohol (b1) having a melting point of more than 50°C and 100°C or less, a polyhydric alcohol (b2) having a melting point of 50°C or less, and a polyhydric alcohol (b3) having a melting point of more than 100°C. The water-soluble film has a high tensile strength and a high tensile elongation, and does not cause bleed-out before the formation of a package.
Patent EP-3525052-A1 (EP)
Inventor: JIANG GUOJIN
IPC: G05B19/418
Filed: 2017-01-24
Abstract: Provided are a data synchronization method and apparatus. The method comprises: after a fault of any one control station is recovered, performing output locking on a faulty control station in a distributed control system of a nuclear power plant, so that the faulty control station may be in a bypass state; comparing variables of the faulty control station with variables of a selected control station without a fault to determine data to be synchronized; and establishing a data transmission channel with the faulty control station, and performing data synchronization on the data to be synchronized based on the established data transmission channel. In the embodiments of the present invention, data can be reliably and accurately synchronized to a faulty control station, the operation is simple, and at the same time, the security and usability of a distributed control system are ensured.
Patent EP-3573759-A1 (EP)
Inventor: WANG ZHAOQIANG
IPC: B01L3/14
Filed: 2017-01-25
Abstract: A tube (100) for sample collection and sample processing in a tube rack (310) comprises: an upper section (110), an intermediate section (120) and a lower section (130). The intermediate section (120) connects the upper section (110) and the lower section (130) of the tube (100), wherein an inner diameter of the intermediate section (120) decreases from a top to a bottom. The tube (100) provides fastening means (140) for fixing the tube (100) in a tube rack (310). The tube (100) includes a pierceable tube cap (210) sealing the tube (100), and the tube rack (310) is configured such that the tube (100) may be pulled off the tube cap (210) by a centrifugation force. The tube (100) comprises contents such as a volume of a density gradient medium (131-10) covered by a separating gel (132-10) to enhance sample separation. The tube rack (310) supports the features of the tube (100) and provides means for automated content identification.
Patent EP-3646479-A1 (EP)
Inventor: FRESIA MARIA
IPC: H04B7/06
Filed: 2017-06-29
Abstract: A method performed by a first radio node for adjusting a set of beams for communication with a second radio node is provided. The first radio node obtains (206) an indication of a first set of beams based on a beam prediction model. The first radio node sends (207) a training symbol on each beam in the first set of beams. The first radio node then receives (208) from the second radio node, feedback relating to the sent training symbols. A second beam is identified (209) based on the feedback and is used for transmission. The received feedback and the second beam are used to adapt (211) the beam prediction model. Further, the first radio node decides (212) whether to adjust the number of beams in the first set of beams based on a relationship between the first and second beam. The adjusted first set of beams is to be used for sending training symbols before an upcoming communication.
Patent EP-3564692-A1 (EP)
Inventor: CHEN WEI
IPC: G01R31/36
Filed: 2017-08-25
Abstract: The present disclosure provides a terminal device and a battery abnormality monitoring method and monitoring system. The battery abnormality monitoring method includes: obtaining a battery voltage of a battery of the terminal device in real time and obtaining a consumption current of the battery in real time, when the terminal device is on; determining whether a voltage jump occurs in the battery of the terminal device according to the battery voltage obtained in real time; further determining whether an abrupt change occurs in the consumption current of the battery when the voltage jump occurs in the battery; and determining that an abnormality occurs currently in the battery when the abrupt change does not occur in the consumption current of the battery. The battery abnormality monitoring method of the present disclosure can monitor whether the abnormality occurs in the battery due to damage by monitoring whether the voltage jump occurs in the battery voltage and whether the abrupt change occurs in the consumption current of the battery, such that timely reminder and maintenance can be achieved, thereby avoiding safety hazards caused by the battery abnormality.
Patent EP-3511873-A1 (EP)
Inventor: LYNES DAVID
IPC: G06Q10/00
Filed: 2018-01-15
Abstract: A method and system is disclosed which makes use of a mobile device, for example a mobile smartphone, carried by a worker, to automatically clock-on and clock-off planned shifts. The method and system is particularly suitable for use for example in the home care sector, and allows attendance at client sites to be recorded accurately and automatically, without any user intervention being required by the worker during his shift.
Patent EP-3335676-A1 (EP)
Inventor: BOILEAU PASCAL
IPC: A61F2/40
Filed: 2008-01-30
Abstract: The method comprises a step of having a glenoid component (10; 200; 220; 240; 260; 280; 440; 480) comprising an elongate anchoring structure (12; 234; 246; 266; 286; 368; 446; 488) which extends lengthwise from a face (11B; 362) of the glenoid component, intended to be turned toward the glenoid surface (G) upon implantation, and which includes a free end part intended to be anchored into the native layer of the glenoid surface. The method further comprises a step of having a bone graft (2; 204; 224; 242; 262; 282; 366; 458; 486; 500) comprising a medial surface (2C; 484) having a shape complementary to the glenoid surface, a distal surface (2B; 212; 239; 256; 276; 294; 364; 456; 482) having a shape complementary to at least a part of the face of the glenoid component and being spaced from the medial surface by a length (I) lower than the length of the anchoring structure, and a recess (E 1 ) which is centered on an axis (E x-x ) and which passes through the bone graft from the medial surface to the distal surface. The method further comprises a step of forming a composite prosthetic unit by introducing the anchoring structure coaxially into the recess of the bone graft.