baber/WOPTO huggingface dataset:
Patent EP-3870297-A2 (EP)
Inventor: SUZUKI MASATAKA
IPC: A61P35/00
Filed: 2019-10-25
Abstract: Methods of treating a cancer, comprising administering to a subject: (i) a virus comprising nucleic acid encoding an antigen-binding molecule comprising:(a) an antigen-binding moiety specific for an immune cell surface molecule, and (b) an antigen-binding moiety specific for a cancer cell antigen; and (ii) an oncolytic virus, and/or (iii) at least one cell comprising a chimeric antigen receptor (CAR) specific for a cancer cell antigen are disclosed. Also disclosed are articles and compositions for use in such methods.
Patent EP-3803652-A2 (EP)
Title: Method and system for secure digital documentation of subjects using hash chains
Inventor: SCOTT GLENN
IPC: H04L9/32
Filed: 2019-05-06
Abstract: The invention relates to a method for documenting subjects using hash chains. The method includes receiving a subject data write request including one or more subject attribute values, generating a fingerprint from a current last block of a hash chain, and generating a payload from the subject data, the payload including the one or more subject attribute values and one or more keys identifying the one or more subject attribute values. The method further includes appending a block to the hash chain. The appended block includes the payload and the fingerprint.
Patent EP-3856194-A2 (EP)
Inventor: ORME MARK W
IPC: C07D487/04
Filed: 2019-09-27
Abstract: Provided herein are compounds and methods of use thereof for the modulation of VAP-1 activity.
Patent EP-3959241-A2 (EP)
Title: Use of an anti-cd19 antibody to treat autoimmune disease
Inventor: KATZ ELIEZER
IPC: C07K16/28
Filed: 2020-04-23
Abstract: Methods for using an anti-CD19 antibody to treat autoimmune disease are disclosed herein. In particular the use of VIB551, a humanised, affinity-optimised, afucosylated IgG1 kappa monoclonal antibody to treat Neuromyelitis optica spectrum disorder.
Patent EP-4041932-A2 (EP)
Title: Blood sample collection tube and uses thereof
Inventor: ABRAMS ROBERT S
IPC: C23C16/04
Filed: 2020-10-13
Abstract: Blood sample collection tubes are described including a tube surface and a coating set comprising a tie coating or layer of SiO x C y  or SiN x C y  applied to the tube surface, a barrier coating or layer of SiO x , and a pH protective layer of SiO x C y  or SiN x C y . The tubes optionally contain a fluid with a pH of 4 to 8, alternatively 5 to 9. The barrier coating or layer prevents oxygen from penetrating into the thermoplastic tube, and the tie coating or layer and pH protective coating or layer together protect the barrier layer from the contents of the tube. Processes of collecting high volumes of blood into the tube, and methods of isolating the various types of nucleic acids from the collected blood sample are described.
Patent EP-3963866-A2 (EP)
Inventor: GUIM BERNAT FRANCESC
IPC: H04L29/08
Filed: 2020-04-29
Abstract: L'invention concerne divers aspects de procédés, de systèmes et de cas d'utilisation pour des déploiements d'informatique en périphérie multi-entités (par exemple, locataires multiples). Parmi d'autres exemples, diverses configurations et caractéristiques permettent la gestion de ressources (par exemple, la commande et l'orchestration de matériel, d'accélération, de réseau, d'utilisation de ressources de traitement), de sécurité (par exemple, l'exécution et la communication sécurisées , l'isolement, les conflits), et de services (par exemple, l'orchestration, la connectivité, la coordination de charge de travail), dans des déploiements d'informatique en périphérie, par exemple par une pluralité de nœuds en périphérie d'un environnement d'informatique en périphérie configuré pour exécuter des charges de travail parmi de multiples locataires.
Patent EP-4045562-A2 (EP)
Inventor: JOHNSON JEREMIAH A
IPC: A61K47/59
Filed: 2020-10-15
Abstract: La présente invention concerne, selon certains aspects, des macromonomères de formule (I), et des sels de ceux-ci ; des procédés de préparation des macromonomères, et des sels de ceux-ci ; des promédicaments à brosse (polymères) ; des procédés de préparation des promédicaments à brosse ; des composés de formule (II) ; des conjugués de formule (III), et des sels de ceux-ci ; des compositions pharmaceutiques comprenant un promédicament à brosse, ou un conjugué ou un sel de celui-ci ; des kits comprenant : un macromonomère ou un sel de celui-ci, un promédicament à brosse, un composé, un conjugué ou un sel de celui-ci, ou une composition pharmaceutique ; des procédés d'utilisation des promédicaments à brosse, ou des conjugués ou des sels de ceux-ci ; et des utilisations des promédicaments à brosse, et des conjugués ou des sels de ceux-ci. Ces entités chimiques peuvent être utiles dans l'administration d'agents pharmaceutiques à un sujet ou à une cellule.
Patent EP-3851261-A2 (EP)
Inventor: LENAERS CORNEEL RENÉ CECILIA
IPC: B27K3/52
Filed: 2021-01-18
Abstract: Procédé de traitement préventif de bois, ledit procédé comprenant les étapes suivantes : une première imprégnation du bois utilisant une première solution comprenant un premier sel, et une deuxième imprégnation du bois utilisant une deuxième solution comprenant un deuxième sel.
Patent EP-3912476-A2 (EP)
Inventor: BAUDIN VICTOIRE
IPC: A23K10/20
Filed: 2021-05-12
Abstract: La présente invention concerne une nourriture pour larves d'insectes et insectes, qui de manière caractéristique contient du champignon aérien et éventuellement une matière sèche. La présente demande concerne également une méthode d'élevage/nourrissage d'une larve ou d'un insecte, une larve, un procédé de fabrication d'un aliment et un aliment obtenu à partir des larves de l'invention.
Patent EP-3998445-A2 (EP)
Inventor: KIM DONGJEONG
IPC: F25D29/00
Filed: 2016-07-29
Abstract: According to an aspect of the present invention, there is provided a refrigerator comprising: a cabinet (11) in which a storage compartment is formed; a refrigerator door (12) for opening and closing the storage compartment; a door opening device (25) having a push rod (27) which moves from an initial position to a door opening position for opening the refrigerator door (12) and a motor (261) for providing power to the push rod (27); a door opening detecting portion (40) for detecting whether the refrigerator door (12) is opened at equal to or more than a reference angle; and a controller (20) configured to control the motor (261) based on information detected from the door opening detecting portion (40), wherein when the door opening detecting portion (40) detects that the refrigerator door (12) is opened at equal to or more than a reference angle while the push rod (27) moves from the initial position to the door opening position, the controller (20) is configured to control the motor (261) so that the push rod (27) returns to the initial position, and wherein the reference angle is greater than an opening angle of the refrigerator door (12) when the push rod (27) moves to the door opening position.
Patent EP-4027499-A2 (EP)
Title: Generator with torsional damper
Inventor: HIMMELMANN RICHARD A
IPC: F16F15/16
Filed: 2021-12-16
Abstract: A rotor assembly (12) of an electric machine (10) includes a rotor body (16) and a shaft assembly (18) positioned at a central axis of the rotor assembly, and operably connected thereto. The shaft assembly includes a main rotor shaft (32) operably connected to the rotor body, a center drive shaft (34) located inside of the main rotor shaft, and a hydraulic damper sleeve (46) located radially between the main rotor shaft and the center drive shaft. The hydraulic damper sleeve defines a plurality of cavities (52) between the hydraulic damper sleeve and the center drive shaft. The hydraulic damper sleeve is configured to urge a fluid into and out of the plurality of cavities thereby damping relative circumferential motion between the main rotor shaft and the center drive shaft. A plurality of flow restrictors are configured to easily allow fluid into the plurality of cavities, while restricting flow of fluid out of the plurality of cavities.
Patent EP-4142844-A2 (EP)
Inventor: HOWELL GLADE H
IPC: A61M25/06
Filed: 2021-04-26
Abstract: Rapidly insertable central catheters ("RICCs") including catheter assemblies and methods thereof are disclosed. A RICC assembly can include a RICC, an introducer, and a coupling system configured to couple the RICC and the introducer together. A catheter tube of the RICC can include a side aperture in a distal-end portion of the catheter tube, which opens into an introducing lumen extending from the side aperture to a distal end of the RICC. The introducer can include an introducer needle having a cannula. The coupling system can include a distal coupler slidably attached to the catheter tube proximal of the side aperture. The cannula extends through a longitudinal through hole of the distal coupler, through the side aperture of the catheter tube, along the introducing lumen of the catheter tube, and through the distal end of the RICC when the RICC assembly is in a ready-to-deploy state thereof.
Patent EP-4153836-A2 (EP)
Inventor: CAFUTA THOMAS
IPC: E05F11/53
Filed: 2021-05-25
Abstract: L'invention vise à permettre une meilleure étanchéité de composants de façade déplaçables. A cet effet, il est prévu une ferrure (10) pour un composant de façade mobile. La ferrure présente un ensemble pivot de guidage (12) pour le composant de façade mobile comprenant au moins deux pivots de guidage (18a) pour une première face du composant de façade et au moins deux pivots de guidage (18b) pour une seconde face du composant de façade située à l'opposé de la première face. L'invention concerne en outre un ensemble tiges d'entraînement (14) destiné à transmettre une force d'actionnement et comportant une première tige d'entraînement (20a) pour la première face du composant de façade mobile et une seconde tige d'entraînement (20b) pour une seconde face du composant de façade mobile. L'invention concerne également un dispositif d'actionnement (16) qui est accouplé à l'ensemble tiges d'entraînement, de manière à transmettre par actionnement la force d'actionnement à la première et à la seconde tige d'entraînement. Les pivots de guidage sont conçus chacun comme tourillons à excentrique (22) ayant un axe de rotation (24) agencé de manière excentrée destiné à être fixé de manière rotative sur le composant de façade mobile et sont destinés à être en prise avec un ensemble rainure de guidage (26) agencé dans la zone du cadre. Les tourillons à excentrique sont accouplés chacun à une des tiges d'entraînement par l'intermédiaire d'un élément d'accouplement (28) et peuvent tourner sous l'effet d'un mouvement des tiges d'entraînement dirigé dans le sens longitudinal. Les tourillons à excentrique qui s'appuient dans l'ensemble rainure de guidage permettent de déplacer le composant de façade mobile transversalement à la direction de guidage, de sorte à induire une pression du composant de façade mobile contre une zone fixe du cadre transversalement à la direction de guidage.
Patent EP-4213660-A2 (EP)
Inventor: THOMAS MICHAEL
IPC: A24F40/465
Filed: 2021-09-15
Abstract: Un dispositif de fourniture d'aérosol est décrit. Un tel dispositif comprend au moins une bobine d'inducteur et un ensemble de chauffage agencé pour recevoir un matériau de génération d'aérosol. L'ensemble de chauffage a une première partie définissant une chambre de chauffage pour recevoir un matériau de génération d'aérosol et ayant une première section transversale interne. La première partie peut être chauffée par la ou les bobines d'induction. L'ensemble de chauffage a également une seconde partie adjacente à la première partie formant un passage ayant une seconde section transversale interne. La seconde section transversale interne est inférieure à la première section transversale interne. Un trajet de fluide étanche est formé entre les première et seconde parties.
Patent EP-4210966-A2 (EP)
Inventor: GODFREY JOHN
IPC: B42D25/324
Filed: 2021-09-10
Abstract: L'invention divulgue un document de sécurité, comprenant des premier et second dispositifs de sécurité, un substrat de document, et une couche protectrice formée d'un matériau durci au moins semi-transparent sur une première surface du substrat de document. La surface de la couche protectrice distale par rapport au substrat de document a une structure de relief de surface intégrale. Le premier dispositif de sécurité est défini par le relief de surface dans une première région de la structure en relief de surface, le second dispositif de sécurité est disposé au niveau de la première surface du substrat de document, et la couche protectrice recouvre le second dispositif de sécurité.
Patent EP-4136123-A2 (EP)
Inventor: YANG HUAN
IPC: C07K16/46
Filed: 2021-04-13
Abstract: The present invention provides EpCAM antibodies with different affinities. The present invention also provides chimeric antigen receptors (CARs) specific to EpCAM. CAR T cells comprising human EpCAM scFv having a low and sufficient affinity to EpCAM can avoid targeting healthy tissues with low EpCAM expression while exhibiting long-term efficacy against tumor tissues with high EpCAM expression. The present invention also relates to an adoptive cell therapy method for treating cancer by administering the CAR-T cells comprising human EpCAM scFv to a subject suffering from cancer, whereby the CAR T cells bind to the cancer cells overexpressing EpCAM and kill the cancer cells.
Patent EP-4039197-A2 (EP)
Inventor: MALKOWSKI JAROSLAW T
IPC: A61B17/04
Filed: 2018-12-14
Abstract: A handle assembly for use with an endoscopic stitching device, the handle assembly comprising: a main rod including a worm gear portion, the main rod operatively coupled to jaws of a tool assembly of the endoscopic stitching device; and a cam wheel assembly including slots configured to cammingly engage blade drive members coupled to needle engaging blades of the tool assembly, the cam wheel assembly including first and second gears configured to engage the worm gear portion of the main rod such that rotation or translation of worm gear portion causes rotation of the first and second gears in opposite directions, wherein the first and second gears are operatively coupled with the blade drive members, whereby axial displacement of the main rod causes reciprocating axial displacement of the blade drive members and transitioning of the jaws between open and closed positions.
Patent EP-4086963-A2 (EP)
Title: Imaging device and electronic device
Inventor: KUMAGAI YOSHIMICHI
IPC: H04N5/374
Filed: 2018-03-09
Abstract: The present disclosure relates to an imaging device and an electronic device that make it possible to obtain a better pixel signal. 
     A photoelectric conversion part that converts received light into a charge; a holding part that holds a charge transferred from the photoelectric conversion part; and a light shielding part that shields light between the photoelectric conversion part and the holding part are provided. The photoelectric conversion part, the holding part, and the light shielding part are formed in a semiconductor substrate having a predetermined thickness. The light shielding part of a transfer region that transfers the charge from the photoelectric conversion part to the holding part is formed as a non-penetrating light shielding part that does not penetrate the semiconductor substrate. The light shielding part other than the transfer region is formed as a penetrating light shielding part that penetrates the semiconductor substrate. The present technology is applicable to an imaging device.
Patent EP-4160389-A2 (EP)
Inventor: PUCHALSKI MATTHEW
IPC: G06F8/60
Filed: 2022-09-27
Abstract: A fleet management system will receive, from each vehicle of a fleet of vehicles, a vehicle identification number (VIN). The system also will receive data elements that comprise: (a) vehicle operational parameters gathered during a run of the vehicle; (b) a hardware identification code that identifies a hardware component of the vehicle; and/or (c) a software identification code that identifies an installed software component in the vehicle. The processor will generate a data block that comprises the VIN and the one or more data elements. The processor will then save the data block to a shared digital ledger that includes VINs and data elements for a plurality of the vehicles in the fleet.
Patent EP-4198286-A2 (EP)
Inventor: MOORE GARETH
IPC: F02K5/00
Filed: 2022-11-17
Abstract: Aircraft power and propulsion systems 100, aircraft 1 comprising such power and propulsion systems 100, and methods of restarting a gas turbine engine 110 of such power and propulsion systems 100 during flight are provided. One such aircraft power and propulsion system 100 comprises: a propulsive gas turbine engine 110 comprising a plurality of spools 14, 19, 26; 15, 17, 27, combustion equipment 16, one or more electric machines 111, 112 mechanically coupled with one or more of the spools 14, 19, 26; 15, 17, 27, and an electrically-powered fuel pump 115 for delivering fuel to the combustion equipment 16; an electrical system 120 connected with the one or more electric machines 111, 112 and the electrically-powered fuel pump 115, the electrical system comprising an energy storage system 130; and a control system 140 configured to: responsive to a determination to the effect that a flame in the combustion equipment 16 has been extinguished, control the electrical system 120 to supply electrical power from the energy storage system 130 to the fuel pump 115 during an engine restart attempt.
Patent EP-4197551-A2 (EP)
Title: Adoptive cell transfer and oncolytic virus combination therapy
Inventor: WAN YONGHONG
IPC: A61P37/02
Filed: 2017-06-23
Abstract: The present invention describes a method for treating cancer comprising adoptive transfer of tumor antigen specific CD8+ T cells and an oncolytic virus vaccine targeting the same antigen.
Patent EP-4298984-A2 (EP)
Inventor: LUPTON JONATHAN K
IPC: A61B1/00
Filed: 2023-06-23
Abstract: A scope system is provided including an elongate tube, a movable member extending longitudinally at least partially within a lumen of the elongate tube, and a light on a distal portion of the elongate tube, the light configured to be controlled by proximal or distal movement of the movable member relative to the elongate tube along a longitudinal axis, rotational movement of the movable member about the longitudinal axis, or any combination of by proximal or distal movement of the movable member relative to the elongate tube along the longitudinal axis and rotational movement of the movable member about the longitudinal axis.
Patent EP-4239966-A2 (EP)
Inventor: PETRIA SILVIU
IPC: H04L41/00
Filed: 2016-07-01
Abstract: An apparatus comprises a gateway device. The gateway device comprises an antenna to connect to a plurality of devices over a wireless network, an interface to couple to a cloud service over a network, a processor, an internet of things, loT, orchestrator executable by the processor to receive an loT application. The loT application defines a plurality of models and interactions between the plurality of models, wherein each of the plurality of models comprises a respective abstract representation of a respective one of a plurality of device types and operational capabilities of the corresponding device type. The loT application is to use a plurality of protocols corresponding to the plurality of device types to perform a particular function. The IoT orchestrator is executable by the processor to determine a mapping of at least a subset of the plurality of devices to the plurality of device types in the set of models of the loT application, deploy a system comprising at least the subset of the plurality of devices based on the mapping and orchestrate interactions between at least the subset of the plurality of devices based on the loT application to cause the system to perform the particular function based on the loT application.
Patent EP-4292626-A2 (EP)
Inventor: MOSEBACH CARSTEN
IPC: A61M5/24
Filed: 2016-06-02
Abstract: The invention relates to a method of assembling a drug delivery device (1, 101),wherein the drug delivery device (1, 101) comprises a control subassembly and a drive subassembly (1.1, 101.1),wherein the drive subassembly (1.1, 101.1) comprises a plunger (10, 110), a drive spring (9, 109) and a rear case (2.2),wherein the control subassembly comprises a cap (11), a needle shroud (7, 307) and a front case (2.1),wherein during assembly, a syringe (3) with an attached needle (4, 104) and a protective needle sheath (5) is inserted into the control subassembly in the distal direction, andwherein afterwards, the drive subassembly (1.1, 101.1) is inserted into the control subassembly in the distal direction.
Patent EP-0009767-A2 (EP)
Inventor: WORTMANN FRANZ-XAVER DR-ING
IPC: F03D1/06
Filed: 1979-09-27
Abstract: 1. Single-blade rotor for wind turbines as characterized by the flapping hinge (A) or an equivalent alternative hinge which lies to the leeward side of the centre of gravity of the rotor (S) and where both points (A, S) are separated from each other, preferably by the measurements  see diagramm : EP0009767,P6,F1  in which N = normal force of the air force, G = rotor weight, g = acceleration due to gravity,  see diagramm : EP0009767,P6,F2  = rotor radian frequency, and by the centre of gravity of the rotor (S) which is elastically supported.
Patent EP-0015724-A2 (EP)
Inventor: VAN ZEGGEREN WILLEM AART
IPC: G07D1/00
Filed: 1980-02-28
Abstract: The invention relates to a coin dispenser for use in vending machines for giving out change when the value of money inserted into the machine exceeds the price of the merchandise purchased. The aim of the invention is to simplify the design of such a dispenser so that different sets of coins can be catered for from a small range of parts. 
     The dispenser comprises vertical coin tubes (12, 13, 14), one for each denomination of coin dispensed, and respective channels (15, 16, 17) extending horizontally beneath each tube. Each channel has an aperture (21, 22, 23) in its lower wall offset from the axis of the tube, (12, 13, 14) and an apertured slide plate (24, 25, 26) is movable in the channel (15, 16, 17) from below the coin tube (12, 13, 14) to over the aperture (21, 22,23) in the lower wall so as to dispense the coins singly from the stacks in the coin tubes. 
     The coin tubes extend down through apertures (18, 19, 20) in the upper wall of their respective channels so that the lower end of the tubes are the lowest point in the coin channels. With this arrangement a range of denominations of coins of differing thicknesses can be catered for by setting the lower end of the tube at a height appropriate to the thickness of the denomination of coins during assembly.
Patent EP-0018268-A2 (EP)
Inventor: BACON ROBERT ELWIN
IPC: G03C5/04
Filed: 1980-04-09
Abstract: Ultrasonographic elements are disclosed which are comprised of first and second layers coated on a support, at least one of the layers being a silver halide emulsion layer. One of the layers contains a diffusible ion capable of altering the sensitivity of a silver halide emulsion while the other layer is capable of immobilizing the diffusible ion. Interposed between the layers is a barrier layer for impeding diffusion of the sensitivity altering ion in the absence of ultrasound. An ultrasonographic image is formed by ultrasonically exposing the element imagewise to accellerate diffusion of the sensitivity altering ion between the layers while the element is in contact with a transport liquid, exposing the element to electromagnetic radiation and photographically processing the element to produce an image corresponding to the image pattern of ultrasonic exposure.