baber/WOPTO huggingface dataset:
Patent CA-2518950-A1 (CA)
Title: Indazole derivatives
Inventor: MIYAMA MOTOKI
IPC: A61P35/02
Filed: 2004-07-30
Abstract: Indazole derivatives represented by the general formula (I) or pharmacologically acceptable salts thereof: (I) wherein R1 is CONR1aR1b(wherein R1a and R1b are each independently hydrogen, lower alkyl, aryl, aralkyl, or a heterocylcic group, or R1a and R1b together with the adjacent nitrogen atom may form a heterocyclic group) or the like; and R2 is hydrogen, CONR2aR2b (wherein R2a and R2b are as defined for R1a and R1b), NR2cR2d (wherein R2c and R2d are each independently hydrogen, lower alkyl, lower alkanoyl, aroyl, heteroaroyl, aralkyl, alkylsulfonyl, or arylsulfonyl) or the like.
Patent CA-2519040-A1 (CA)
Inventor: SOKOLOV GARY
IPC: A63F13/00
Filed: 2003-04-04
Abstract: A game apparatus with: (a) an indicia selecting means including a rotatable wheel (1) having a plurality of selectable regions (20, 21, 22 etc), each region (20, 21, 22) associated with paying card indicia (31, 32, 33 respectively); (b) a means for randomly selecting a selectable region (20, 21, 22) of the wheel (1); (c) a wagering area (40) adapted for positioning wagers concerning the indicia (31, 32, 33) associated with the region (20, 21, 22) selected a single operation of the indicia selecting means. A method for operating the game system is also described.
Patent CA-2520291-A1 (CA)
Title: Camphanylidene and phenylalkyl inositol polyphosphate compounds, compositions, and methods of their use
Inventor: TRAYNOR-KAPLAN ALEXIS E
IPC: C07F9/655
Filed: 2004-03-25
Abstract: This invention relates to new camphanylidene and phenyl alkyl inositol polyphosphate derivatives that inhibit the absorption of sodium ions in epithelial cells and regulate inducible nitric oxide synthase (iNOS) in macrophages. The invention provides methods for inhibiting sodium ion absorption by epithelial cells and/or regulating inducible nitric oxide synthase (iNOS) in macrophages, by treating epithelial cells or administering to a patient in need of such treatment a therapeutically effective amount of camphanylidene and/or phenyl alkyl inositol polyphosphate compound.  Representative camphanylidene and phenyl alkyl inositol polyphosphate compounds include, for example, 1,2-camphanylidene-myo-inositol 3,4,5,6-tetrakisphosphate octakis (propionoxymethyl) ester (INO-4996), 2,3-camphanylidene-myo-inositol 1,4,5,6~-tetrakisphosphate octakis (propionoxymethyl) ester (INO-4984) and 2-O-butyryl-1-O-(3-~phenylpropyl)-myo-inositol 3,4,5,6-tetrakisphosphate octakis (propionoxymethyl) ester (INO-4997).
Patent CA-2522471-A1 (CA)
Title: Methods for the treatment of pain comprising opioid antagonists
Inventor: SCHOENHARD GRANT L
IPC: A61P25/04
Filed: 2004-04-14
Abstract: Methods and compositions for treating subjects with pain, including neuropathic pain, using the antagonists naloxon, naltrexon or nalmefene or combinations of these antagonists and opioid agonists, wherein the amount of an opioid antagonist enhances the neuropathic pain-alleviating potency of an opioid agonist.
Patent CA-2522739-A1 (CA)
Title: Pharmaceutical compositions comprising cereal beta (1-3) beta (1-4) glucan
Inventor: REDMOND MARK J
IPC: A61K31/716
Filed: 2004-04-30
Abstract: The present invention relates to pharmaceutical compositions comprising a .beta. (1-3) .beta. (1-4) glucan and a pharmaceutically active agent or a botanical extract. A method to extract and purify cereal .beta.-glucan is also described. The high purity of the cereal .beta.-glucan obtained according to the present invention allows for the preparation of clear, colourless viscous liquid preparations. These liquid preparations are stable to gelling effects when kept at ambient temperatures and low ash concentrations, and can be used to prepare the pharmaceutical compositions of the present invention.
Patent CA-2523459-A1 (CA)
Title: Method of accumulating allergen-specific t cell antigen determinant in plant and plant having the antigen determinant accumulated therein
Inventor: TAKAGI HIDENORI
IPC: A23L7/196
Filed: 2004-04-23
Abstract: As techniques of accumulating a human T cell epitope in rice albumen, a method comprising accumulating a T cell epitope-attached peptide (7crp) directly in seeds, and a method comprising inserting 7crp into the variable region of glutelin, which is a major storage protein of rice, and expressing and accumulating the same as a part of the glutelin storage protein are developed.  It is strongly expected that the rice capable of producing the T cell epitope-attached peptide thus developed would serve as a practically usable edible vaccine against cedar pollen allergy.
Patent CA-2524047-A1 (CA)
Title: Immunosuppressant compounds and compositions
Inventor: PAN SHIFENG
IPC: B29C65/50
Filed: 2004-05-19
Abstract: The present invention relates to immunosuppressant, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by lymphocyte interactions, particularly diseases associated with EDG receptor mediated signal transduction.
Patent CA-2528101-A1 (CA)
Title: Cutaneous metabolic bio-activator
Inventor: REDZINIAK GERARD
IPC: A61K38/08
Filed: 2003-12-23
Abstract: The invention relates to a cosmetic composition comprising a bio-active system which combines (i) a stable form in aqueous solution of ATP (adenosine-tri-phosphate) with optionally an ATP precursor, e.g. Gp¿4?G (diguanosine tetraphosphate), or Ap¿4?A (diadenosine tetraphosphate), and (ii) at least one biomimetic peptide comprising at most six amino acids, mimicking a cutaneous polypeptide or a cutaneous protein, or a biomolecule which is agonist or antagonist in relation to the aforementioned polypeptide or protein. According to the invention, the composition takes the form of a water-in-oil or oil-in-water emulsion, the bio-active system being included in the aqueous phase.
Patent CA-2529005-A1 (CA)
Inventor: RAMACHANDRAN NATARAJAN
IPC: G07F19/00
Filed: 2004-05-07
Abstract: An automated banking machine (10) includes a lockable first fascia portion (20) which when unlocked enables access to a chest lock input device (104), inputs to which enable opening a chest door (18) of the machine. Opening the first fascia portion also enables access to an actuator (116) which enables moving a second fascia portion (22) for conducting service activities. A  controller (72) in the machine selectively illuminates light emitting devices (118, 126) for purposes of facilitating user operation of the machine. Sensing devices (128) adjacent a card reader slot (28) on the machine enables the controller to detect the presence of a fraud device or unauthorized card reading devices. Sensing devices (254) adjacent a keypad (32) enables the controller to detect the presence of an unauthorized manual input intercepting device.
Patent CA-2532062-A1 (CA)
Inventor: LAPOINTE LAVAL
IPC: A23C9/127
Filed: 2006-01-16
Abstract: La présente invention concerne une composition alimentaire comprenant un microorganisme probiotique et un produit prébiotique dans une portion de produit laitier ou une fraction de produit laitier. Particulièrement, la composition de la présente invention est utile pour le maintien ou le rétablissement de l'équilibre de la flore intestinale.
Patent CA-2533178-A1 (CA)
Title: Antibiotic product, use and formulation thereof
Inventor: BURNSIDE BETH A
IPC: A61K9/22
Filed: 2004-07-20
Abstract: An antibiotic product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antibiotic product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosage form, a delayed release dosage form, an d a sustained release dosage form, with each of the dosage forms having a different release profile, wherein each reaches a Cmax at different times.</ SDOAB>
Patent CA-2538180-A1 (CA)
Inventor: ROSS ROBERT N
IPC: G02B23/24
Filed: 2004-08-30
Abstract: A lens assembly (22) and method for manufacture. The lens assembly includes at least one lens element (23), with multiple sawn planar faces (30-33) formed parallel to an optical axis (21) and spaced equidistantly from the optical axis so the lens element has a polygonal cross section. Each lens element has a centered, rotationally symmetric characteristic so the overall assembly has a corresponding characteristic. The manufacture includes the step of utilizing oversized conventional cylindrical lens elements and other optical elements formed into lens systems. The faces are sawn to reduce the overall size. A  circumscribing sheath provides a segmental lumen along each face.
Patent CA-2543333-A1 (CA)
Inventor: SYLTHE OLAV A
IPC: H04L12/16
Filed: 2006-04-13
Abstract: A method for presenting an attachment within an email message on a display o f a portable electronic device includes displaying the email message using a messaging application, sending a conversion request to an attachment server in order t o view the attachment in an attachment viewer of the portable electronic device, receiving a converted attachment from the attachment server; and upon receiving the converted attachment from the attachment server, inserting a thumbnail image in a message body of the emai l message.
Patent CA-2544810-A1 (CA)
Title: Feeder apparatus, and methods of constructing and utilizing
Inventor: PAVLIK SAMUEL T
IPC: A01K5/02
Filed: 2006-04-25
Abstract: A livestock hay saver which protects hay from the elements and contamination.  The apparatus has timer-operated doors which provide control to completely automated means for providing feed to horses and cattle. Its battery-operated, solar-recharged power system makes it completely portable and minimizes the need for user attention or maintenance.
Patent CA-2548087-A1 (CA)
Inventor: BATCH RICHARD M
IPC: G16H70/00
Filed: 2004-11-19
Abstract: A system and method for compiling and analyzing treatment parameters associated with medical treatments provided to a plurality of patients is provided. A report of the analysis may be provided to a technician or physician for determining medical treatment guidelines representing acceptable values for a selected treatment parameter in accordance with the analysis. The system may further automatically determine medical treatment guidelines and/or adjust preestablished medical treatment guidelines in accordance with the analysis.
Patent CA-2549379-A1 (CA)
Title: System and method of secure information transfer
Inventor: ZIEGLER ROBERT
IPC: G06K5/00
Filed: 2004-12-11
Abstract: Information may be securely transferred from a first device (102) to a second device (110) over an open network (108) by transferring software to the first device (102) and executing the software. Data representing the information is entered at the first device (102) and transferred to the second device (110).  The second device (110) uses the data to determine the information.
Patent CA-2555198-A1 (CA)
Inventor: DEVE HERVE E
IPC: B32B15/02
Filed: 2005-01-03
Abstract: Metal-cladded metal matrix composite wires that include a hot worked metal cladding associated with the exterior surface of a metal matrix composite wire comprising a plurality of continuous, longitudinally positioned fibers in a metal matrix.
Patent CA-2555984-A1 (CA)
Title: Immunotherapie combinee de cellules de fusion et de l'interleukine 12 pour le traitement du cancer
Inventor: OHNO TSUNEYA
IPC: C12N5/08
Filed: 2005-02-11
Abstract: La présente invention a trait à des procédés et des protocoles de traitement pour l'immunothérapie du cancer par l'administration d'une dose thérapeutiquement efficace de cellules de fusion formées par la fusion de cellules dendritiques et des cellules non dendritiques autologues en combinaison avec l'interleukine 12.
Patent CA-2556800-A1 (CA)
Title: Tensioning tool for a counterbalance system for sectional doors
Inventor: MULLET WILLIS J
IPC: E06B9/62
Filed: 2005-02-25
Abstract: A door system (10) including, a door (d) movably mounted on a track assembly (15), a counterbalance system (20) connected to the door and having at least one spring (25), a tool adapter (26) proximate at least one end of the counterbalance system, a detachable winding assembly (30) adapted to selectively engage and selectively rotate the tool adapter to adjust tensioning of the spring, and a locking assembly (36) interacting with the counterbalance system to maintain a selected tensioning of the counterbalance system upon detaching the winding assembly from the tool adapter.
Patent CA-2559904-A1 (CA)
Title: Production of novel radiation-hardening binding agents
Inventor: DETREMBLEUR CHRISTOPHE
IPC: C08G18/78
Filed: 2005-03-05
Abstract: The invention relates to a method for producing novel binding agents comprising groups reacting with polymerising ethylenically unsaturated compounds under the action of actinic radiation and optionally also isocyanate-reactive groups. The invention also relates to the use of said binding agents in coating substances.
Patent CA-2560235-A1 (CA)
Title: Mattress
Inventor: OWEN PHILIP
IPC: A47C27/14
Filed: 2005-03-14
Abstract: A mattress (2), comprising: a resilient body having at least one upper surface portion for supporting a person (such as a small child or baby); and a plurality of surface channels (30) disposed in the or each upper surface portion and extending parallel thereto. The upper surface portions (for example three, including separate surface portions for supporting the head and the body) are inclined relative to the horizontal (or preferably, suitably anatomically sloped). The surface channels (30) have a component of direction in the direction of rising slope. In consequence, warm air that has been heated by contact with the person's body, in order to rise, passes along the surface channel (30) and out to the surrounding atmosphere. Thus, heat is dissipated away from the person's body and helps to prevent overheating.
Patent CA-2560759-A1 (CA)
Title: Human anthrax toxin neutralizing monoclonal antibodies and methods of use thereof
Inventor: WESTRA HANS
IPC: C12N15/13
Filed: 2005-03-03
Abstract: The invention fully humanized monoclonal antibodies that neutralize Bacillus anthracis. Also provided are methods of treating or preventing a Bacillus anthracis infection. The invention also provides methods of passive vaccination of a subject against Bacillus anthracis.
Patent CA-2561154-A1 (CA)
Inventor: DELCAMP JONATHAN W
IPC: A23L2/66
Filed: 2005-04-15
Abstract: This invention is directed to an acid beverage composition, comprising; (A) a hydrated protein stabilizing agent; (B) at least one flavoring material comprising a fruit juice, a vegetable juice, citric acid, malic acid, tartaric acid, lactic acid, ascorbic acid, glucono delta lactone or phosphoric acid;  and (C) a slurry of an aqueous protein material wherein the slurry of the aqueous protein material is prepared by a process, comprising; (1) preparing an aqueous extract from a protein containing material, (2) adjusting the pH of the aqueous extract to a value of from about 4 to about 5 to precipitate the protein material, (3) separating the precipitated protein material and forming a suspension of the precipitated protein material in water, (4) adjusting the pH of the suspension to a value of from about 4.0 to about 6.0 to form a slurry of an aqueous protein material, and optionally (5) pasteurizing the slurry of the aqueous protein material; wherein the acid beverage composition has a pH of from 3.0 to 4.5. Also disclosed are several processes for preparing an acid beverage composition.
Patent CA-2565761-A1 (CA)
Inventor: ZIMMERMANN HOLGER
IPC: C07D471/04
Filed: 2005-04-23
Abstract: This invention relates to substituted azaquinazolines, to a process for their preparation, to pharmaceutical compositions containing them, and to their use for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, in particular against cytomegaloviruses.
Patent CA-2566358-A1 (CA)
Inventor: HARDING IAN
IPC: G01N27/26
Filed: 2005-05-20
Abstract: Electrochemical test cells are made with precision and accuracy by adhering an electrically resistive sheet having a bound opening to a first electrically conductive sheet. A notching opening is then punched through the electrically resistive sheet and the first electrically conductive sheet. The notching opening intersects the first bound opening in the electrically resistive sheet, and transforms the first bound opening into a notch in the electrically resistive sheet. A second electrically conductive sheet is punched to have a notching opening corresponding to that of first electrically conductive sheet, and this is adhered to the other side of the electrically resistive sheet such that the notching openings are aligned. This structure is cleaved from surrounding material to form an electrochemical cell that has a sample space for receiving a sample defined by the first and second conductive sheets and the notch in the electrically resistive sheet.
Patent CA-2569265-A1 (CA)
Title: Encapsulated optical package
Inventor: ROLSTON DAVID ROBERT CAMERON
IPC: G02B6/42
Filed: 2004-07-26
Abstract: A method for providing an encapsulated optoelectronic chip is provided. The optoelectronic chip is secured on a substrate. A translucent coating substance is then applied on said optoelectronic chip and the translucent coating substance is then polished away to enable an optical coupling.
Patent CA-2571524-A1 (CA)
Title: Load resistor
Inventor: WOBBEN ALOYS
IPC: H01C3/10
Filed: 2005-07-08
Abstract: The invention relates to a high performance resistor comprising several electrical resistor elements (10, 11) which are serially connected to a first and to a second side (10a, 10b; 11a, 11b) and to a first and to a second end (10c, 10d; 11c, 11d). A first connection (16a) is provided on the first end (10c, 11c) and a second connection (16b) is provided on the second end (10d;  11d) in order to connect the resistor elements (10, 11). The first and the second connection (16a, 16b) comprises an inner section and an outer section, whereby the inner section of the first connection (16a) is curved at a predetermined angle in relation to the first side (10a, 11a) of the resistor element (10, 11) and the outer section of the first connection (16a) is arranged on a plane which is essentially parallel to the plane of the resistor element (10, 11). The inner section of the second connection (16b) is curved at a predetermined angle in relation to the second side (10b, 11b) of the resistor element (10, 11) and the outer section of the second connection (16b) is arranged on a plane which is arranged in an essentially parallel manner on the plane of the resistor element (10, 11).
Patent CA-2571925-A1 (CA)
Title: Dry-base aerated food product dispensing method and apparatus
Inventor: KATEMAN PAUL
IPC: A47J31/40
Filed: 2005-06-30
Abstract: A method of producing and dispensing a food product provides a supply of prod~uct base in the form of a dry powder, mixes a selected amount of that powder with a se~lected amount of water to produce a selected volume of powder base/water mix. That volume is then flowed along a confined turbulence passage so that the powder base dis~solves thoroughly in the water to form a selected volume of liquid product base. At a lo~cation further along the passage, air is injected into the liquid product base to give the liquid product base a selected amount of aeration whereby a selected volume of a ho~mogenous aerated liquid product exits the passage. Flavor may be added to the aerated liquid product and that product may be at least partially frozen to form a frozen confec~tion. Apparatus for carrying out the method is also disclosed.
Patent CA-2573969-A1 (CA)
Inventor: KOCJAN DARKO
IPC: A61P9/00
Filed: 2005-07-15
Abstract: The present invention relates to oxidative degradation products of atorvastatin calcium and the process of the preparation thereof. The present invention also relates to atorvastatin calcium substantially free of oxidative degradation products and the pharmaceutical compositions containing such atorvastatin calcium.
Patent CA-2574054-A1 (CA)
Inventor: ASAKURA TOSHIKAGE
IPC: C07C381/00
Filed: 2005-07-11
Abstract: The invention pertain to novel photoacid generator compounds of the formula (I, II or III), Wherein R1 is for example C1-C18alkylsulfonyl or phenylsulfonyl, phenyl-C1-C3alkylsulfonyl, , naphthylsulfonyl, anthracylsulfonyl or phenanthrylsulfonyl, all optionally substituted, or R1 is a group (a, b or c); X1, X2 and X3 independently of each other are O or S; R'1 is e.g. phenylenedisulfonyl, naphthylenedisulfonyl, diphenylenedisulfonyl, or oxydiphenylenedisulfonyl, all optionally substituted; R2 is halogen or C1-C10haloalkyl; X is halogen; Ar1 is for example biphenylyl or fluorenyl, or is substituted naphthyl; Ar'1 is heteroarylene, optionally substituted; R8, R9, R10 and R11 for example are C1-C6alkyl which is unsubstituted or substituted by halogen; or R8, R9 and R10 are phenyl which is unsubstituted or substituted by C1-C4alkyl or halogen; or R10 and R11 together are 1,2-phenylene or C2-C6alkylene which is unsubstituted or substituted by C1-C4alkyl or halogen.
Patent CA-2575376-A1 (CA)
Inventor: FUTERMAN YURI
IPC: A61K31/573
Filed: 2005-07-26
Abstract: Novel crystalline forms II, III, IV, V, VI, VII and VIII of 6alpha,9 alpha -difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17alpha-propionyloxyandrosta-1,4-diene-17beta-carboxylic acid, a chemical intermediate useful in the preparation of fluticasone propionate, and novel methods of making these forms, substantially free of water, are disclosed.
Patent CA-2575475-A1 (CA)
Title: Method for diagnosing liver fibrosis
Inventor: HUEDIG HENDRIK
IPC: G01N33/68
Filed: 2005-08-12
Abstract: The invention concerns a method for the detection of the presence and/or the severity of a liver disease in a patient comprising measuring in an isolated sample TIMP-1 (Tissue Inhibitor of Metalloproteinase I), A2M (a-2-macroglobulin), PLT (number of blood plateletes , PI (prothrombin index), optionally at least one additional parameter selected from the group consisting of urea and GGT (.gamma.-glutamyltranspeptidase) and optionally measuring at least one additional biochemical or clinical parameter and diagnosing the presence and/or severity of a liver disease based on the presence or measured levels of these parameters. The method can be used for monitoring therapeutic treatment of liver fibrosis and staging of liver fibrosis.
Patent CA-2576465-A1 (CA)
Title: Fused triazole derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
Inventor: ASHTON WALLACE T
IPC: C07D471/00
Filed: 2005-08-19
Abstract: The present invention is directed to novel fused triazole derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DPP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Patent CA-2578065-A1 (CA)
Title: Roller stand
Inventor: ROGER SCOTT T
IPC: B65G13/12
Filed: 2005-08-16
Abstract: An out-feed roller support stand having a sturdy, stable base that folds for compact storage. A support mast that telescopes into and is adjustable within the base supports a work support head that includes and adjustable cross bar on which a row of pivoting caster wheels are mounted. An alternative embodiment includes a ramp for guiding sagging ends of work-pieces up onto the caster wheels. Both the height and angle between the adjustable cross bar and floor are adjustable after the position of the support mast has been adjusted in order to position the support head in roughly the correct location.