baber/WOPTO huggingface dataset:
Patent WO-2023168291-A1 (WO)
Title: Modificateurs covalents de akt1 et leurs utilisations
Inventor: TAUNTON JOHN
IPC: A61K47/64
Filed: 2023-03-01
Abstract: Sont divulgués dans la présente divulgation, des composés et des méthodes destinés à la modulation de protéines AKT1, telles que AKT1 E17K. Dans certains aspects, la présente divulgation concerne une protéine AKT1, un composé étant lié à un résidu lysine de la protéine AKT1. Selon un autre aspect, la présente divulgation concerne des composés de formule (I) et (II), utiles pour la modulation de protéines AKT1. Selon un autre aspect, la présente divulgation concerne une méthode d'atténuation de l'activité AKT1 à l'aide des composés présentés dans la description.
Patent WO-2023215877-A1 (WO)
Inventor: ORKIN STUART H
IPC: C07K14/47
Filed: 2023-05-05
Abstract: La présente invention concerne des compositions et des procédés de dégradation ciblée de protéines spécifiques d'érythroïdes. Les compositions de l'invention comprennent un domaine de liaison pour une protéine érythroïde d'intérêt, par exemple, BCL11A, et un domaine de liaison pour une ubiquitine ligase E3 enrichie en érythroïdes. Les compositions et les méthodes de l'invention peuvent être utilisées pour augmenter le taux d'hémoglobine fœtale et traiter des troubles tels que l'hémoglobinopathie.
Patent DK-201670528-A1 (DK)
Title: A thermo treatment process for wood
Inventor: KLAAS PETER
IPC: B27K5/00
Filed: 2016-07-15
Abstract: Thermo treatment process for wood comprising the following steps: a. Placing the wood batch to be treated in a treatment chamber; b. Exchanging the atmosphere inside the treatment chamber by evacuating the air, replacing the evacuated air by an inert gas atmosphere in gas form, at 8 to 12 bar pressure; c. Heating the inert gas atmosphere up to 165 to 175 ºC, d. increasing the pressure in the inert gas atmosphere to 14-16 bar; e. maintaining the temperature in step c. and the pressure in step d. for from 90 to 150 minutes; f. cooling the inert gas atmosphere to a temperature of 20 to 35 ºC g. retrieving the treated wood batch
Patent PH-12014502679-A1 (PH)
Title: Neutralization method
Inventor: HIROTAKA HIGUCHI
IPC: C22B23/00
Filed: 2014-12-01
Abstract: The purpose of the present invention is to provide a neutralization method which attains a reduction in the amount of a costly, highly alkaline neutralizing agent to be used and renders efficient neutralization possible, when a barren liquid is neutralized, the barren liquid resulting from a treatment step for forming sulfides of nickel and cobalt from an aqueous sulfuric acid solution that contains nickel, cobalt, and one or more impurity metals comprising one or more of iron, magnesium, and manganese. This method comprises a first neutralization step (S11) in which a calcium carbonate slurry is added as a first neutralizing agent to the barren liquid to neutralize the barren liquid to an end point in the pH range of 5.0-6.0 and a second neutralization step (S12) in which the solution obtained in the first neutralization step (S11) is neutralized using a second neutralizing agent to obtain both a sediment containing the metals that remained in the barren liquid and a neutralized final liquid from which the metal ions have been removed.
Patent PH-12015500022-A1 (PH)
Title: Method and apparatus for encoding video and method and apparatus for decoding video determining inter-prediction reference picture list depending on block size
Inventor: CHAN-YUL KIM
Filed: 2015-01-05
Abstract: The present invention discloses a method for determining a reference picture for inter-prediction, and an inter-prediction method according to same. The present invention discloses an inter-prediction method, comprising: determining a reference picture list which is used by a current prediction unit, when a current slice is a B slice; outputting inter-prediction index information of the current prediction unit, which indicates a reference picture list of an L0 list or an L1 list, when the size of the current prediction unit is 4x8 or 8x4; and outputting inter-prediction index information which indicates a reference picture list of one of the L0 list, the L1 list, or both lists, when the size of the current prediction unit is not 4x8 or 8x4.
Patent PH-12015502188-A1 (PH)
Title: Coated tool and method of producing the same
Inventor: SALEH ABUSUILIK
IPC: B21D37/20
Filed: 2015-09-18
Abstract: The present invention provides a coated tool which is obtained by coating the surface of a base with a diamond-like carbon film. The diamond-like carbon film has a nanoindentation hardness of from 50 GPa to 100 GPa (inclusive); the content of hydrogen atoms and the content of nitrogen atoms in the diamond-like carbon film decrease from the base side toward the thickness direction; and the surface of the diamond-like carbon film has a hydrogen atom content of 0.5 pcnt by atom or less and a nitrogen atom content of 2 pcnt by atom or less.
Patent PH-12017000196-A1 (PH)
Title: M2d2 (minimizing meter downtime device)
Inventor: MANILA ELECTRIC COMPANY (MERALCO)
IPC: H01R33/945
Filed: 2017-07-05
Abstract: A device that will allow meters to continuously register consumption of customer during inspection of Form 9S metering facilities consisting of the following: 1. a meter cabinet; 2. an ST 13 terminal assembly mounted inside the meter cabinet; 3. a plurality of toggle switches mounted on the meter cabinet and connected and ST 13 terminal assembly; 4. a plurality of binding posts mounted on the meter cabinet and connected to the plurality of toggle switches and ST 13 terminal assembly; 5. a plurality of wires which are connected to the binding posts and with clips on the other end of the wires; 6. a plurality of handles mounted on the meter cabinet.
Patent PH-12017500318-A1 (PH)
Title: Heat insulation material and method for producing same
Inventor: KURIMOTO YOSHIRO
IPC: F16L59/02
Filed: 2017-02-21
Abstract: A heat insulation material which is characterized by being formed of a laminate wherein fiber layers formed of heat-resistant fibers are laminated, and which is also characterized in that: the fiber layers are solidified by means of a thermosetting resin; and the laminate contains no or little thermoplastic resin that has an upper temperature limit that is lower than the upper temperature limit of the thermosetting resin.
Patent PH-12018500428-A1 (PH)
Title: Electronic vapour provision system
Inventor: BAKER DARRYL
IPC: A24F40/90
Filed: 2018-02-27
Abstract: An electronic vapour provision system comprises a control unit including: a battery for providing electrical power to a heater which is used to produce vapour, and a controller. The controller is configured to collect information, during user operation of the electronic vapour provision system, relating to: (i) power consumption from the battery due to operation of the heater to produce vapour, and (ii) re-charging of the battery. The controller is further configured to maintain a model of power consumption from the battery by the electronic vapour provision system and of the timings of re-charging the battery, wherein said model is formed or updated from said collected information. The model is further configured to predict from the model whether an estimated power consumption from the battery by the electronic vapour provision system will discharge down to a threshold level of charge before an estimated next re-charging time, and if so, perform a user notification and/or mitigation action in response to said prediction.
Patent PH-12019050160-A1 (PH)
Title: A safety transport case with an electromagnetic clutching alarm
Inventor: ZHOU SANYUAN
IPC: B65D43/22
Filed: 2019-08-15
Abstract: This invention discloses a safety transport case with an electromagnetic clutching alarm, including a case body 12; a placement cavity 14; a storage battery 25; a relay 27; a rotation cavity 22; a rotation shaft 21; a case cover 23; wherein the placement cavity 14 with an opening facing to a first side is arranged in the case body 12; the storage battery 25 is fixedly arranged on a top wall of the placement cavity 14; the relay 27 is in electrical connection with a bottom surface of the storage battery 25; the rotation cavity 22 communicating vertically is arranged at the top wall on the first side of the placement cavity 14; the rotation shaft 21 is rotatably arranged in the rotation cavity 22. The present invention has a sensitive reaction, a high degree of automation. This apparatus is reliable in transportation and has a significant alarm performance.
Patent PH-12019050278-A1 (PH)
Title: A method and system in securing a user authentication
Inventor: MALIBERAN ESMAEL V
IPC: H04L9/32
Filed: 2019-11-07
Abstract: A method and system to secure a client-server communication though login authentication using the modified SHA1 algorithm. This was done by allocating 32 buffer registers for variables A, B, C and D at 5 bytes each. The expansion was done by generating 4 buffer registers in every round inside the compression function for eight (8) times. Findings revealed that the hash value of the modified algorithm was not cracked or hacked during the experiment and testing using a powerful online cracking tool, brute force attack tool and rainbow table attack tool.
Patent PH-12019500421-A1 (PH)
Title: Distributed systems for the efficient production and use of microbe-based compositions
Inventor: FARMER SEAN
IPC: C12M3/00
Filed: 2019-02-27
Abstract: The invention relates to systems and methods for effective production and use of microorganisms and/or the fermentation broth in which they are produced. Advantageously, the system is cost-effective, scalable, quick, versatile, efficacious, and helpful in reducing resistance to chemical compounds and residue that concerns consumers.
Patent PH-12019502778-A1 (PH)
Title: Confectionery having grape-like mouthfeel
Inventor: YAMABE FUMITAKA
IPC: A23G3/34
Filed: 2019-12-10
Abstract: Provided is a confectionary having a grape-like mouthfeel, i.e., a confectionery that contains a solidified gel composition and a collagen casing coating the solidified gel composition and that, through the solidified gel composition having the dynamic viscoelastic pattern of raw grape flesh, has a bursting mouthfeel like that of a raw skin-attached grape. This dynamic viscoelastic pattern is, for example, a dynamic viscoelastic pattern in which the loss tangent value at an angular frequency of 63.1 rad/S is reduced by 34 pcnt to 83 pcnt with respect to the loss tangent value at an angular frequency of 3.98 rad/S.
Patent PH-12019550215-A1 (PH)
Title: Device for generating hydrogen gas
Inventor: CHIA CHIN YANG
IPC: C01B3/06
Filed: 2019-10-16
Abstract: A device for generating hydrogen gas having two or more storages, each storage storing a reactant or mix of reactants, and each storage coupled to a means of injecting the stored reactant or mix of reactants into a reaction chamber in a controlled manner and at an optimum rate, so that a chemical reaction occurs in the reaction chamber that produces hydrogen gas efficiently.
Patent PH-12020500153-A1 (PH)
Title: Antimicrobial application system with recycle and capture
Inventor: MASSEY JUSTIN
IPC: C02F1/46
Filed: 2020-01-21
Abstract: A capture unit for use with an antimicrobial application unit may include an upstream filter and a downstream filter. The upstream filter may be positioned to receive effluent from the application unit and to filter solid components from the effluent. The resultant upstream effluent filtrate may then be passed downstream to the downstream filter. The downstream filter may be used to filter an antimicrobial component from the upstream effluent filtrate and the resultant downstream effluent filtrate may be suitable for disposal as wastewater discharge. The antimicrobial is preferably a quaternary ammonium compound, is more preferably an alkylpyridinium chloride, and is most preferably cetylpyridinium chloride.
Patent PH-12020500222-A1 (PH)
Title: Nucleic acid molecules and uses thereof
Inventor: SEREGIN ALEXEY
IPC: C07K14/755
Filed: 2020-01-29
Abstract: The present disclosure provides nucleic acid molecules comprising a first inverted terminal repeat (ITR), a second ITR, and a genetic cassette encoding a miRNA and/or a therapeutic protein. In certain embodiments, the therapeutic protein comprises a clotting factor, e.g., a FVIII polypeptide, a FIX polypeptide, or a fragment thereof. In some embodiments, the first ITR and/or the second ITR is an ITR of a non-adeno-associated virus (AAV). The present disclosure also provides methods of treating bleeding disorders such as hemophilia comprising administering to the subject the nucleic acid molecule or a polypeptide encoded thereby.
Patent PH-12020551726-A1 (PH)
Title: Treatment of atopic dermatitis
Inventor: SIMARD JOHN
IPC: A61P37/08
Filed: 2020-10-19
Abstract: Symptoms of atopic dermatitis in a human subject are reduced by administering to the subject a pharmaceutical composition that includes a pharmaceutically acceptable carrier and a therapeutically effective amount of an agent that selectively binds IL-1a.
Patent DE-102004001619-A1 (DE)
Title: Gap filter for liquids or gases has a filtration element formed from multiple spaced apart segments with the total minimum gap flow area being proportioned to the internal flow area of the filtration element
Inventor: KUZMIN ANDREY
IPC: B01D29/35
Filed: 2004-01-09
Abstract: A gap filter for liquid or gaseous media has a filtration element (5) formed from multiple spaced apart segments with the total of the minimum flow areas between adjacent segments being in the proportion of P = 80-120% of the internal, uniform cross section, feed flow area of the filtration element.
Patent DE-102004003228-A1 (DE)
Title: Fire extinguishing and fire insulating coating material, useful for protecting e.g. buildings (houses, hospitals, hotels and churches) against fire, comprises powdered shells of sea mollusks, mussels, oysters or snails
Inventor: ALEGRE CARLOS
IPC: C09D5/18
Filed: 2004-01-22
Abstract: Fire extinguishing and fire insulating coating material (I) comprises powdered shells of sea mollusks, mussels, oysters or snails (particularly e.g. Archidae and Glycymeridae), where the shells are powdered and crushed to a grain size of 3-4 mu or finer (in powder form) or to a size similar to the sand grains (in granulate form). Fire extinguishing and fire insulating coating material (I) comprises powdered shells of sea molluscs, mussels, oysters or snails (particularly e.g. Archidae, Glycymeridae, Mytilidae, Pteridae, Pectinidae, Ostereidae, Cardiidae, Solenidae, Mesodesmatidae, Tellinidae, Donacidae, Psammobidae, Veneridae, Haliotidae, Fissurellidae, Cassidae and Chitonidae), where the shells are powdered and crushed to a grain size of 3-4 mu or finer (in powder form) or to size similar to the sand grains (in granulate form).
Patent DE-102004005393-A1 (DE)
Title: Elektrochemischer Energiespeicher
Inventor: GERMAN JOHANN
IPC: H01M10/50
Filed: 2004-02-04
Abstract: Ein elektrochemischer Energiespeicher ist mit Wärmeaustauschereinheiten und mehreren elektrochemischen, jeweils in wenigstens zwei benachbarten Reihen nebeneinander angeordneten Speicherzellen, die zwischen den Wärmeaustauschereinheiten angeordnet sind, versehen. Die Wärmeaustauschereinheiten weisen von einem Temperiermedium durchströmte Wärmeaustauscherkanäle, Umströmungs-Verteilerkanäle, Vorlaufverteilerkanäle und Rücklaufsammelkanäle auf. Die Wärmeaustauschereinheiten sind mit den dazwischen angeordneten Speicherzellen in einen Batteriekasten einsetzbar und der Batteriekasten ist druckdicht und wasserdicht ausgebildet und mit einer Wasserablauf- und Entlüftungseinrichtung versehen.
Patent DE-102004007418-A1 (DE)
Title: Scaffold has reinforcing frames fastened to perforated inner tubes of steel, and side strut of aluminum has shape conforming to curvature of inner tube
Inventor: SCHAEFFER FRANZ
IPC: E04G5/00
Filed: 2004-02-16
Abstract: The scaffold has height adjustable supports, comprising an outer tube of aluminum and inner tube (4) of steel, and between which are installed reinforcing frames of aluminum or steel. The reinforcing frames can be fastened to the perforated inner tubes of steel. A side strut (6) of aluminum has a shape conforming to the curvature of the inner tube. The connection between the struts of the reinforcing frames and inner tube is through a special connecting bolt (3) and a locking pin rotatable around a locking bolt (2) and conforming to the shape of the inner tube.
Patent DE-102004009939-A1 (DE)
IPC: C08G18/48
Filed: 2004-02-26
Abstract: The invention relates to swelling-resistant integral polyurethane foams obtainable by reacting polyisocyanate prepolymers (a) with a polyol mixture (b) comprising a polyether polyol (b1) based on a bifunctional starter molecule and a polyether polyol (b2) based on a trifunctional to pentafunctional starter molecule, with the polyols (b1) and (b2) being prepared by alkoxylation by means of ethylene oxide (hereinafter referred to as EO) and propylene oxide (hereinafter referred to as PO), having an ethylene oxide content of more than 50% by weight and at least 5% of the ethylene oxide being present as an EO end cap.
Patent DE-102004014132-A1 (DE)
Title: Verfahren und Vorrichtung zum Stimulieren von Otolithenorganen durch Lineare Beschleunigung
Inventor: NAGANUMA HIDEAKI
IPC: A61B19/00
Filed: 2004-03-23
Abstract: Ein Basisabschnitt (A) trägt einen Drehabschnitt (B). Der Drehabschnitt (B) trägt einen Neigeabschnitt (C). Der Neigeabschnitt (C) trägt einen Sitzabschnitt (D). Der Sitzabschnitt umfasst einen Sitz (75), eine Sitzlehne (76) und eine Stufe (79). Die Sitzlehne (76) weist einen Halteabschnitt (E) auf. Der Halteabschnitt (E) umfasst einen Hinterkopfhalter (96) und einen Schläfenhalter (97). Ein Versuchsobjekt wird auf den Sitzabschnitt (D) gesetzt, wobei sein Hinterkopfgebiet und seine Schläfen von dem Halteabschnitt (E) gehalten werden. Ein Kopf des Versuchsobjekts wird auf eine Seite aus einer horizontalen Ebene des Kopfes in dem stereotaktischen Reid-Koordinatensystem nach unten geneigt, um eines der linken oder rechten Otolithenorgane in die horizontale Ebene des Kopfes zu platzieren. In dieser geneigten Position werden unterschiedliche lineare Beschleunigungsstimuli auf linke bzw. rechte Otolithenorgane zum unabhängigen Funktionstest von linken und rechten Otolithenorganen angewendet.
Patent DE-102004014862-A1 (DE)
Title: Sole of shoe for patient after leg operation, comprising pressure indicating mechanism
Inventor: LIESENFELD WERNER
IPC: A61B5/107
Filed: 2004-03-26
Abstract: When convalescing after a leg operation the patient is allowed only to apply a particular force on the affected leg. The sole (100) of the special shoe is assembled of an inner gel layer (1), a first elastic insert (2), a longitudinally yielding steel foil (3), a printed circuit board (4), and a second steel foil (7). Two leaf springs (9, 10) inserted between the printed circuit board (4) and the steel foil (7) prevent the unit from a lateral motion. The information about the pressure acting on the sole (100) is obtained by a sensor (5, 6), processed in a control unit (12), and transmitted to an display device.
Patent DE-102004015569-A1 (DE)
Title: Synchronisiereinrichtung für Antriebsstrangkomponenten
Inventor: SHOWALTER DAN J
IPC: F16D13/52
Filed: 2004-03-30
Abstract: Die Synchronisiereinrichtung, die für Antriebsstrangkomponenten, wie Wechselgetriebe und Verteilergetriebe, eines Kraftfahrzeuges geeignet ist, umfasst zwei Kugel-Rampen-Mechanismen, welche eine Synchronisierkraft verstärken und diese verstärkte Kraft auf eine von zwei Reibscheibenpaketen ausübt, welche eine Synchronisation verschiedener rotierender Elemente bewirkt. Die Synchronisiereinrichtung zeigt eine relativ niedrige Betätigungskraft. Jeder Kugel-Rampen-Mechanismus umfasst zwei Kugel-Rampen-Glieder mit Drehbewegungsgrenzen, die auch ihre axiale Trennung begrenzen, und eine dazwischen angeordnete Druckfederanordnung. Die Druckfederanordnung und die Bewegungsgrenzen der Kugel-Rampen-Glieder begrenzen die Kraft, die von den Kugel-Rampen-Mechanismen erzeugt und auf die Reibscheibenpakete ausgeübt wird, um eine abrupte und unkontrollierte Betätigung der Reibscheibenpakete und eine entsprechende abrupte Synchronisation der rotierenden Elemente zu verhindern.
Patent DE-102004016226-A1 (DE)
Title: Packaging foil for a window frame sealing strip, laterally rolled/folded into a hose/bellows, is wrapped around it so that an adhesive acrylic layer is readily available for strip attachment
Inventor: SCHMID OLIVER
IPC: B65D85/67
Filed: 2004-04-01
Abstract: The packaging foil (20) for a window frame sealing strip (10) - which is laterally rolled into a hose or folded into a bellows - is wrapped around it so that the adhesive acrylic layer (12) is readily available for strip attachment.
Patent DE-102004016346-A1 (DE)
Title: Removal process for small amounts of viscous material involves detecting clearance and amount removed to regulate amount on basis of intended value
Inventor: WIEDENHOEFER MARKUS
IPC: B05C5/02
Filed: 2004-04-02
Abstract: The removal process involves the use of a dispenser unit (2) via which the material is removed. The clearance between the surface and the removal device, and the amount of the viscous material removed, are detected, and these values are used as the basis for setting the amount removed, using at least one intended value. The devices used are also described.
Patent DE-102004017561-A1 (DE)
Title: Sausage recipe for human consumption incorporates wild garlic in minced sausage meat
IPC: A23L13/60
Filed: 2004-04-07
Abstract: In a recipe for sausage meat, wild garlic leaves are incorporated in the minced sausage meat.
Patent DE-102004022004-A1 (DE)
Title: Schichtanordnung für eine organische lichtemittierende Diode
Inventor: BLOCHWITZ-NIMOTH JAN
IPC: H01L51/52
Filed: 2004-05-03
Abstract: Die Erfindung betrifft eine Schichtanordnung für eine organische lichtemittierende Diode (OLED) in top-emittierender Ausführung sowie eine Anzeigeeinrichtung und eine Beleuchtungseinrichtung mit der Schichtanordnung. Die Schichtanordnung umfaßt eine untere Elektrode (A), eine obere Elektrode (K), die transparent ist, und einen organischen Schichtbereich (O), welcher in Kontakt mit der unteren und der oberen Elektrode (A; K) zwischen den beiden Elektroden (A; K) angeordnet ist und in dem mittels Rekombination von Elektronen und Löchern Licht erzeugt werden kann, das durch die obere Elektrode (K) austritt, wobei die untere Elektrode (A) einen Schichtaufbau aufweist, bei dem eine untere Elektrodenschicht eine Metallschicht ist. Im Schichtaufbau der unteren Elektrode (A) ist auf der Metallschicht eine Schutz- und Modifikations-Schicht angeordnet, die mit dem organischen Schichtbereich (O) in Kontakt ist.
Patent DE-102004023856-A1 (DE)
Inventor: STROBL GERHARD
IPC: H01L31/042
Filed: 2004-05-12
Abstract: The invention relates to a solar cell which comprises photoactive semiconductor layers extending between the front and the back contact, and an integrated protective diode (bypass diode), said protective diode having a polarity opposite to that of the solar cell and is provided at its front with a p-conducting semiconductor layer, and the protective diode is connected to the front contact. The aim of the invention is to provide a highly stable protective diode and to prevent a migration of metal atoms. For this purpose, a tunnel diode (38) extends on the p-conducting semiconductor layer (36) of the protective diode (32), said tunnel diode being connected to the front contact (14) via an n+ layer.