baber/WOPTO huggingface dataset:
Patent CA-2510477-A1 (CA)
Title: Process for the preparation of oligonucleotides
Inventor: MCCORMAC PAUL
IPC: C07H21/00
Filed: 2003-12-16
Abstract: A process for the synthesis of an oligonucleotide is provided in which an oligonucleotide is assembled on a swellable solid support using the phosphoramidite approach in the presence of an activator, wherein the activator is not tetrazole or a substituted tetrazole. Preferred activators are pyridinium, imidazolinium and benzimidazolinium salts; benzotriazole and derivatives thereof; and saccharin or a saccharin derivative. Preferred swellable solid supports comprise functionalised polystyrene, partially hydrolysed polyvinylacetate or poly(acrylamide).
Patent CA-2510548-A1 (CA)
Title: System, apparatus, program, and method for authentication
Inventor: IKEDA TATSURO
IPC: G06F21/44
Filed: 2005-06-23
Abstract: According to an aspect of the invention, a management of each authentication subprocess assures the each authentication subprocess, and assurance contents can be verified by verification side, so that trustworthiness of the whole authentication process can be improved. An authentication system includes authentication entity devices which separately execute authentication subprocesses P1 and P2 and a verification device which verifies the executed contents of each of the authentication subprocesses P1 and P2. The entity device includes a confidential information management unit which manages confidential information, an authenticator generating unit which generates an authenticator using the confidential information, and a context generating unit which generates a specific context pursuant to a specific format from the authenticator and the executed contents.
Patent CA-2510855-A1 (CA)
Title: Fast driving method for amoled displays
Inventor: REZA CHAJI G
IPC: G09G3/3225
Filed: 2005-07-06
Abstract: Disclosed is a technique for reducing programming time in active matrix organic light emitting (AMOLED) pixel circuits.
Patent CA-2511110-A1 (CA)
Title: Fishing jig lure
Inventor: BECKER DAMION D
IPC: A01K85/01
Filed: 2005-06-29
Abstract: A fishing jig lure has a fish hook mounted on a glass body with an epoxy resin. Light emitting particulates mixed with the epoxy resin emit visible light when subjected to an external light source.
Patent CA-2514848-A1 (CA)
Inventor: RICHARDSON PETER
IPC: A61K31/7076
Filed: 2004-03-05
Abstract: Use of compounds of formula: (I) wherein R is C1-4 alkoxy and X is H or OH;  for the prevention, treatment, or amelioration of cancer, inflammation, auto-immune disease, ischemia-reperfusion injury, epilepsy, sepsis, septic shock, neurodegeneration (including Alzheimer's Disease), muscle fatigue or muscle cramp is described. The compounds are effective at very low doses, and so can be administered at doses at which serious side effects are not observed.
Patent CA-2516163-A1 (CA)
Title: High viscosity xanthan polymer preparations
Inventor: IELMINI MARIA VERONICA
IPC: A23L29/00
Filed: 2004-03-18
Abstract: Increasing the molecular length of xanthan polymer makes a higher viscosity xanthan composition. Xanthan with higher specific viscosity characteristics provides more viscosity at equivalent concentration in food, industrial and oilfield applications. Methods for increasing the viscosity of xanthan include inducing particular key genes and increasing copy number of particular key genes.
Patent CA-2516481-A1 (CA)
Title: Dielectric particle focusing
Inventor: GASCOYNE PETER R C
IPC: G01N15/14
Filed: 2004-02-18
Abstract: Methods and apparatuses for particle focusing. Particles are focused within a fluid-flow channel using dielectrophoretic forces from electrodes disposed within the fluid-flow channel, and the focused particles can be detected with an optical detector.
Patent CA-2516667-A1 (CA)
Title: Treatment using dantrolene
Inventor: CAMERANSI BENJAMIN G JR
IPC: A61K6/00
Filed: 2004-03-01
Abstract: Low volume safe for injection formulations of dantrolene yield significant advantages over the currently approved and marketed dantrolene for MH  threatening anesthetic crisis. Once dantrolene can be made immediately available to patients triggered of MH, the anesthesiologist will be able to focus exclusively on the management of the patient's physiologic status in this complex and evolving crisis, not on the laborious and time consuming reconstitution process of the rescue agent. Additionally, a safe for injection low volume formulation of dantrolene can be made widely available to non-anesthesiologist practitioners who have occasion to use dantrolene intravenously in the treatment of other potentially life threatening conditions, including in the field. The low volume, safe for injection formulations of dantrolene, as well as other formulations of dantrolene, have significant advantages over currently used approaches to the prevention and treatment of pumphead, and other neurological, cognitive and motor dysfunction incident to iatrogenically or trauma induced situations of altered blood flow, including those incurred during surgical procedures involving CPB or related procedures, as well as those incurred during non-normothermic episodes caused iatrogenically or by disease.
Patent CA-2517108-A1 (CA)
Inventor: YAMAMOTO YUKIHIRO
IPC: A61K35/28
Filed: 2003-02-25
Abstract: A medium for stem cells to be used in regenerating intervertebral disk which contains an autoserum prepared by sterilizing and immobilizing the serum of an individual having the intervertebral disk to be regenerated, a medium for ce ll culture and at least one antibiotic; and a method of regenerating intervertebral disk which comprises suspending stem cells, which have been collected from the subject or another individual of the same or different species, in the above medium or embedding the stem cells in a cell carrier, either directly or after culturing in the medium for stem cells to be used i n regenerating intervertebral disk, and then transplanting the stem cell suspension or the embedment thus obtained into the marrow cavity of the intervertebral disk.
Patent CA-2520169-A1 (CA)
Title: Power steering apparatus in vehicle having handlebar and vehicle having handlebar
Inventor: YANAI HIDEO
IPC: B62K5/01
Filed: 2005-09-19
Abstract: A power steering apparatus for being protected from mud or dust, or rainwater. A sub-steering unit is provided together with a torque sensor of the power steering apparatus used in a vehicle. A steering shaft portion includes an input shaft and an output shaft, each being rotatably supported. A torque sensor portion is connected for joining the input shaft and the output shaft with the torque sensor portion sensing an amount of torque. A power assist portion is engaged with the output shaft for assisting the steering based on the amount of torque sensed by the torque sensor portion and the like. A sub-steering portion is engaged so as to connect the input shaft with the output shaft while circumventing the torque sensor portion and reducing the amount of torque. The power steering apparatus includes a column cover for covering the sub-steering portion as well as the torque sensor portion.
Patent CA-2521369-A1 (CA)
Title: The use of peripheral opiois antagonists, especially methylnaltrexone to treat irritable bowel syndrome
Inventor: SANGHVI SUKETU P
IPC: A61K31/765
Filed: 2004-04-08
Abstract: Methods of treating irritable bowel syndrome with peripheral opioid antagonists, such as methylnaltrexone, are provided. Formulations comprising peripheral opioid antagonists, such as methylnaltrexone, and irritable bowel syndrome therapeutic agents are also provided.
Patent CA-2526003-A1 (CA)
Title: Polyester-polyacrylate dispersions with reactive diluents based on compounds containing lactone groups
Inventor: MUENZMAY THOMAS
IPC: C09D167/06
Filed: 2005-11-08
Abstract: The present invention related to a process for preparing aqueous polyester-polyacrylate dispersions having a cosolvent content of 0 to 5% by weight, based on the weight of the dispersion, by preparing a polymer P) in a first step by polymerizing A) a mixture of vinyl monomers that are capable of free-radical copolymerization, in the presence of B) one or more oligoesters prepared from compounds containing lactone groups and having a hydroxyl number of 145 to 710 mg KOH/g, an acid number of <= 0.5 mg KOH/g solids and an average OH functionality of 2.5 to 5 mg KOH/g solids, and then mixing polymer P) in a second step with C) one or more polyester polyols having a hydroxyl number of 10 to 500 mg KOH/g solids and an acid number of > 0.5 to <= 30 mg KOH/g solids and dispersing the resulting polymer mixture in water in a further step, before or after addition of a neutralizing agent. The present invention also relates to the aqueous polyester-polyacrylate polymer dispersions obtained in accordance with the process of the invention and to aqueous coating compositions containing the aqueous polyester-polyacrylate polymer dispersions of the invention.
Patent CA-2526009-A1 (CA)
Title: Display device with rail support
Inventor: GUNTER JOHN BARTHOLOMEW
IPC: G09F9/33
Filed: 2003-10-15
Abstract: Disclosed is a display device, elongate mount, and display module for displaying alphanumeric information to passengers of a mass transit vehicle.  The display modules are mounted along a single edge to a elongate mount. The elongate mount includes at least one end cap which is made of a vibration dampening material. The louver of the display device includes a substantially continuous pressure member in order to place substantially continuous elongate contact to an area of an LED board that houses at least one heating element.  The at least one heating element is covered by a thermally conductive foam that transmits heat from the elements to a heat sink of the display module.
Patent CA-2529621-A1 (CA)
Inventor: LEECH DOUGLAS D
IPC: B65D25/26
Filed: 2005-12-09
Abstract: A support for stabilizing a pressurized LP tank in an upright position during transport and storage. The support comprises an extended flat body with a central opening in its top surface for mating engagement with a base portion on the bottom of the LP tank. The extended body provides an extended support to prevent tipping of the tank. Preferably the support will also include a friction enhanced bottom surface to prevent sliding of the support and tank during transport. The support is preferably made from a thermoplastic elastomer.
Patent CA-2532009-A1 (CA)
Title: Indirector light fixture
Inventor: RUSSELLO THOMAS
IPC: F21V21/10
Filed: 2006-01-03
Abstract: An indirector light fixture is described wherein the fixture is comprised of a reflector housing and a ballast housing connected together by a support arm. The reflector housing may be positioned relative to the ballast housing by movement of the support arm and maintained therein by a ratchet and pawl mechanism or other rotational restriction device. The ballast housing and ballast electronics are connected to the lamp within the reflector housing by ballast feed wires which are maintained internal of the entire fixture thereby preventing the wires from becoming entangled during installation or after installation. Additional structure is provided to further allow adjustment of the head angle relative to the ballast housing.
Patent CA-2532751-A1 (CA)
Inventor: RIGAS LEONIDAS E
IPC: G06F21/12
Filed: 2006-01-13
Abstract: Systems and methods are described for shielding a vulnerability in an application through disablement of one or more features. In an implementation, a method includes identifying a vulnerability in at least one of a plurality of features for an application module. A communication is formed for receipt by a plurality of clients to shield execution of the application module from the identified vulnerability. The communication describes that the at least one feature is to be disabled from execution in conjunction with the application module.
Patent CA-2537494-A1 (CA)
Inventor: SELF COLIN HENRY
IPC: G01N33/543
Filed: 2004-08-31
Abstract: The invention relates to assays in which complexes between an analyte and a binding agent specific for the analyte are detected by a reporter molecule, which is capable of binding to the binding agent when the binding agent is complexed with analyte but not when the binding agent is complexed with an analyte analogue. The invention provides a method of modifying such a binding agent in order to create a tailored site where the reporter molecule may bind to the binding agent. This provides control over the location and nature of the reporter binding site. Antibodies, including bispecific antibodies, are preferred binding agents. The invention also provides novel methods for labelling antibodies close to their antigen binding site using bi- and tri-functional reagents. Modified binding agents produced by the methods described are also provided.
Patent CA-2539953-A1 (CA)
Inventor: WALSH MICHAEL
IPC: A61K31/519
Filed: 2004-08-27
Abstract: The present invention provides methods for optimizing clinical responsiveness to chemotherapy in an individual through genotypic analysis of polymorphisms in at least one gene. The methods of the present invention may further comprise determining the level of at least one long-chain methotrexate polyglutamate (MTXPG) in a sample obtained from the individual. The present invention also provides methods for generating a pharmacogenetic index for predicting clinical responsiveness to chemotherapy in an individual through genotypic analysis of polymorphisms in at least one gene. In addition, the present invention provides methods for optimizing therapeutic efficacy of chemotherapy in an individual by calculating the level of at least one long-chain MTXPG in a sample obtained from the individual.
Patent CA-2540134-A1 (CA)
Inventor: HONG SUNG-HO
IPC: B01J23/22
Filed: 2003-12-05
Abstract: Disclosed is a vanadium/titania-based catalyst for removing nitrogen oxides, and a process for removing nitrogen oxides in a flue gas using the same. The vanadium/titania-based catalyst containing a vanadium trioxide and/or vanadium tetraoxide has excellent activity to remove nitrogen oxides in a wide temperature range, particularly, at the low temperature window.
Patent CA-2540975-A1 (CA)
Inventor: WAATTI TODD ANTHONY
IPC: A43B23/04
Filed: 2004-10-08
Abstract: La présente invention concerne un article chaussant comportant une tige extensible et/ou une structure de semelle articulée. La tige peut être faite de deux épaisseurs, une extérieure et l'autre intérieure. L'épaisseur extérieure, qui forme au moins une partie de l'extérieur de la tige, comporte une pluralité d'incisions traversant l'épaisseur extérieure. L'épaisseur intérieure, qui est placée contre la face intérieure de l'épaisseur extérieure, est visible au travers des incisions. La structure de la semelle peut comporter une zone de liaison et une pluralité d'éléments de semelle distincts. La zone de liaison, qui vient contre la tige, peut occuper une longueur longitudinale de la tige. Les éléments de semelle, partant de la zone de liaison, sont séparés entre eux par une pluralité lamelles qui remontent dans la structure de semelle.
Patent CA-2541057-A1 (CA)
Inventor: WARKENTIN DWIGHT H
IPC: A61B5/0215
Filed: 2004-10-07
Abstract: An implantable cardiac stimulation device capable of delivering ESS, monitoring for myocardial ischemia and responding to the detection of myocardial ischemia by modifying the delivery of ESS. Modification of ESS  delivery may include disabling ESS, initiating ESS, and/or modifying ESS  control parameters.
Patent CA-2543800-A1 (CA)
Inventor: VIGH GYULA
IPC: G01N27/447
Filed: 2004-10-25
Abstract: An electrophoresis apparatus for measuring, characterizing and/or altering a composition of a sample. The apparatus comprises an anode compartment having an anode and a cathode compartment having a cathode. The anode and cathode are spaced at a distance from one another to define an electric field having a direction along a longitudinal axis, and between the anode and cathode compartments can be at least one separation compartment. Each compartment includes means for adding or removing a solution, a first dimension orthogonal to the direction of the electric field, a second dimension orthogonal to the electric field and the first dimension, and a third dimension parallel to the electric field and orthogonal to the first and second dimensions. A ratio of the first and second dimensions define an aspect ratio, at least one aspect ratio being less than one. An ion-permeable barrier is positioned between each compartment to prevent convective mixing therebetween. At least one of the compartments can be made of an electrically insulating material having a thermal conductivity greater than about 1 W/mK and a specific heat greater than about 100 J/kgK.
Patent CA-2543844-A1 (CA)
Title: A process for making lube oil basestocks
Inventor: STAVENS ELIZABETH
IPC: B01J35/00
Filed: 2004-10-29
Abstract: A process for producing lube oil basestocks involving solvent extracting a waxy feed to produce at least a lube oil boiling range raffinate, hydrotreating the lube oil raffinate to produce a hydrotreated raffinate, and dewaxing the hydrotreated raffinate.
Patent CA-2545363-A1 (CA)
Title: Rumen bacteria mutants and process for producing succinic acid employing the same
Inventor: LEE SANG JUN
IPC: C12R1/01
Filed: 2004-05-20
Abstract: The present invention relates to novel rumen bacterial mutants resulted from the disruption of a lactate dehydrogenase gene (ldhA) and a pyruvate formate-lyase gene (pfl) (which are involved in the production of lactic acid, formic acid and acetic acid) from rumen bacteria; a novel bacterial mutant (Mannheimia sp. LPK7) having disruptions of a lactate dehydrogenase gene (ldhA), a pyruvate formate-lyase gene (plf), a phosphotransacetylase gene (pta), and a acetate kinase gene (ackA); a novel bacterial mutant (Mannheimia sp. LPK4) having disruptions of a lactate dehydrogenase gene (ldhA), a pyruvate formate-lyase gene (pfl) and a phosphoenolpyruvate carboxylase gene (ppc) involved in the immobilization of CO2 in a metabolic pathway of producing succinic acid; and a method for producing succinic acid, which is characterized by the culture of the above mutants in anaerobic conditions. The inventive bacterial mutants have the property of producing succinic acid at high concentration while producing little or no organic acids, as compared to the prior wild-type strains of producing various organic acids. Thus, the inventive bacterial mutants are useful as strains for the industrial production of succinic acid.
Patent CA-2546345-A1 (CA)
Title: Intravascular filter with bioabsorbable centering element
Inventor: WASDYKE JOEL M
IPC: A61F2/01
Filed: 2004-09-30
Abstract: Bioabsorbable centering elements for use in centering an implantable intravascular device within a body vessel are disclosed. The bioabsorbable centering element may include a number of support members configured to self-expand and engage the wall of the vessel when deployed. The support members may be formed from a biodegradable material adapted to degrade in vivo within a pre-determined period of time.
Patent CA-2548001-A1 (CA)
Title: Method and apparatus for determining an efficacious atrioventricular delay interval
Inventor: CHINCHOY EDWARD
IPC: A61N1/368
Filed: 2004-12-03
Abstract: Determining an optimal atrioventricular interval is of interest for proper delivery of cardiac resynchronization therapy. Although device optimization is gradually and more frequently being performed through a referral process with which the patient undergoes an echocardiographic optimization, the decision of whether to optimize or not is still generally reserved for the implanting physician. Recent abstracts have suggested a formulaic approach for setting A-V interval based on intrinsic electrical sensing, that may possess considerable appeal to clinicians versus a patient average nominal A-V setting of 100 ms. The present invention presents a methods of setting nominal device settings based on entering patient cardiac demographics to determine what A-V  setting may be appropriate. The data is based on retrospective analysis of the MIRACLE trial to determine what major factors determined baseline A-V settings.
Patent CA-2548011-A1 (CA)
Inventor: YOUNG ERICK RICHARD ROUSH
IPC: A61K31/496
Filed: 2004-12-02
Abstract: Disclosed are compounds of formula (I): wherein the variables R1, R2, R3 and Z  are described herein, which are useful as inhibitors of the kinase activity of the I.kappa.B kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
Patent CA-2548406-A1 (CA)
Inventor: LECOUVE JEAN-PIERRE
IPC: C07K5/06
Filed: 2004-12-09
Abstract: Procédé de synthèse des composés de formule (I) : dans laquelle R représente un atome d~hydrogène ou un groupement protecteur de la fonction amino. Application à la synthèse du perindopril et de ses sels pharmaceutiquement acceptables.
Patent CA-2551283-A1 (CA)
Inventor: PRIBNOW DANIEL FREDERIK CHRIST
IPC: E21B47/10
Filed: 2004-12-22
Abstract: A method of determining a fluid inflow profile along the length of a permeable inflow region of an underground wellbore compring: -transferring heat into or from the permeable inflow region of the wellbore during a well shut in period;  -starting production of hydrocarbon fluids via said permeable inflow region; -measuring substantially simultaneously the temperature of the fluids at various points of the inflow region; - determining at selected intervals of time after production start up a temperature profile of the inflow region on the basis of the thus measured temperatures; and - determining a fluid inflow profile of said inflow region on the basis of a comparison of the determined temperature profiles at selected intervals after production start up. The heater cable may comprise a layer of compacted mineral powder and temperatures may be measured with an optical fiber.
Patent CA-2554559-A1 (CA)
Inventor: DIORIO CHRISTOPHER RICHARD
IPC: A61K9/50
Filed: 2005-01-25
Abstract: A multiparticulate O-desmethylvenlafaxine (ODV) succinate or formate is described. Methods of treating depression and reducing the gastrointestinal side-effects of ODV are also described.
Patent CA-2554688-A1 (CA)
Title: A fluid dispenser
Inventor: BONNEY STANLEY GEORGE
IPC: B05B11/00
Filed: 2005-02-04
Abstract: A fluid dispenser (1) for dispensing a metered volume of a fluid product (2) has a storage chamber (57) for storing the fluid product in; a dispensing outlet (27) through which the fluid product is dispensable from the dispenser;  a metering chamber (73) which is adapted to provide the metered volume of the fluid product for dispensing through the dispensing outlet by movement of the metering chamber between a contracted state and an expanded state, movement of the metering chamber from the contracted state to the expanded state placing the metering and storage chambers in fluid communication to enable the metering chamber to receive from the storage chamber an excess volume of the fluid product comprising the metered volume and a surplus volume; and a bleed arrangement (55a, 55b) adapted to bleed the surplus volume of the fluid product from the metering chamber. The metering chamber is defined by a boundary wall having a first section (43) movably mounted in the dispenser to move the metering chamber between the expanded and contracted states. The first section of the metering chamber boundary wall and the storage chamber are provided by a container unit (43, 57) which is movably mounted in the dispenser.