baber/WOPTO huggingface dataset:
Patent EP-3604383-A1 (EP)
Inventor: YOSHIOKA HIROKI
IPC: A61K47/60
Filed: 2018-03-22
Abstract: Provided is a method for industrially producing a polyoxyethylene derivative (1) having a plurality of hydroxy groups at a terminal. The method, which is for producing a polyoxyethylene derivative represented by formula (1), comprises steps (A), (B), (C), and (D): step (A) in which a polyhydric alcohol having five or seven hydroxy groups is subjected to a hydroxy-protecting reaction to protect four or six of the hydroxy groups by forming a cyclic benzylidene acetal, thereby obtaining a compound that has a hydroxy group at the 1-position and has a protective group having a cyclic benzylidene acetal structure; step (B) in which ethylene oxide is polymerized with the compound obtained in step (A), in an amount of 11 to 3,650 mol to obtain a polyoxyethylene derivative; step (C) in which the terminal hydroxy group of the polyoxyethylene derivative obtained in step (B) is converted to a functional group reactive with a physiologically active substance; and step (D) in which the protective group of the polyoxyethylene derivative is removed. (In formula (1), L 1  is a divalent linker; X is a functional group reactive with a physiologically active substance; a is 1 or 2; and n is 11-3,650.)
Patent EP-3601537-A1 (EP)
Inventor: KAMIYA TAKAHIRO
IPC: C12N15/24
Filed: 2018-03-27
Abstract: The present invention relates to genetically engineered cell populations derived from an immortalised/ cancerous cell that do not express MHC class I molecules but that are modified to express membrane-bound IL-15, membrane-bound 4-1 BBL ligand, and at least one other membrane bound molecule, such as an interleukin or anti-CD3 antibody. The co-culture of said cells with a population of immune cells results in the activation and expansion of at least one subpopulation of immune cells. Expanded populations of NK cells derived from the co-culture of a mixed cell culture with the stimulatory cell lines may be used in methods of treating cancer or an infectious disease. In a separate embodiment, a plurality of nucleic acids for use in preparing the engineered cell population are provided.
Patent EP-3856323-A1 (EP)
Inventor: AGARWAL GAURAV
IPC: A61K9/00
Filed: 2018-09-24
Abstract: The invention concerns a device (1) for delivering a cosmetic filler composition to the skin, comprising a base (2) carrying a plurality of hollow microneedles (3), the device being characterized in that each microneedle (3) has an external largest transverse dimension (D n ) less than or equal to 1500 micrometers, and in that the microneedles comprise a filler composition.
Patent EP-3682601-A1 (EP)
Inventor: BATARDIÈRE SIMON
IPC: H04L45/243
Filed: 2018-10-12
Abstract: The routing of data (51) received from a first network device (CPE1) into a second network device (CPE2), each having a link aggregation engine, comprises detecting (52) whether or not the data has already undergone a link aggregation operation in the first device (CPE1) or upstream, based on markers present in the data, and then selecting (53) an output link (LOUT) from all the output links of the second device (CPE2) participating in link aggregation if the data has not already undergone link aggregation, or selecting (54) the output link (LOUT) from all the output links of the second device (CPE2) participating in link aggregation except for the output link (Li) towards the first device (CPE1) if the data has already undergone link aggregation, and transmitting (55) the data on the output link (LOUT) selected.
Patent EP-3684856-A1 (EP)
Inventor: SIMONIS UDO
IPC: C08K5/103
Filed: 2018-09-21
Abstract: The invention relates to a roofing membrane that contains a base polymer. In order to improve resistance to hydrolysis, the roofing membrane contains an ester-based polymer plasticizer and at least one hydrolysis stabilizer having at least one carbodiimide.
Patent EP-3615952-A1 (EP)
Inventor: ROBINSON MARTIN
IPC: H02H1/00
Filed: 2018-04-24
Abstract: Embodiments of the present disclosure may enable an electrical component within an electrical distribution equipment cabinet to be audibly monitored via an electrical fault detection device mounted on the housing of the cabinet. The electrical fault detection device may comprise a senor to detect a signal emitted from an electrical fault within the cabinet, a transducer to convert the detected signal into an electrical audio signal, and an output socket adapted for an external device that may generate an audible sound based on the detected signal. The detected sensor may be an ultrasound sensor and the detected signal may be anultrasound emitted from the electrical fault.
Patent EP-3678590-A1 (EP)
Inventor: KAM ANDREW
IPC: A61F2/08
Filed: 2018-09-06
Abstract: Devices for fixation of a soft tissue graft at a surgical site. A suspensory graft fixation device (100) for securing a replacement graft ligament in a bone tunnel includes an elongated anchor member (102) with top (114) and bottom (116) surfaces, and adjacent first (110) and second (112) suture receiving apertures extending from the top surface to the bottom surface thereof. A graft supporting loop element is attached to the anchor member and is formed of a suture (104) having first and second limbs (124, 126). The suture is threaded through the first and second suture receiving apertures such that first and second loops (132, 134) are formed in the suture. The first and second loops extend from the bottom surface, while the first and second limbs extend from the top surface. A splice (136) is formed in the second limb extending from the top surface and the first limb extends through the splice.
Patent EP-3514862-A1 (EP)
Title: Electrode for all-solid-state battery and method for manufacturing same
Inventor: CHO SUNG-JU
IPC: H01M4/04
Filed: 2018-05-15
Abstract: An electrode for an all solid type battery according to the present disclosure is designed such that fibrous carbon materials serving as a conductor are densely arranged cross into a 3-dimensional structure in the form of a mesh of a nonwoven fabric-like shape, and an inorganic solid electrolyte and electrode active material particles are impregnated and uniformly dispersed in the structure. By this structural feature, the electrode for an all solid type battery according to the present disclosure has very good electron conductivity and ionic conductivity.
Patent EP-3706913-A1 (EP)
Title: Method for converting a naturally-aspirated flotation cell to a forced-gas flotation cell, and apparatus thereof
Inventor: WALKER MATHEW
IPC: B01F7/00
Filed: 2018-11-07
Abstract: The disclosure relates to an adapter (200) for converting a naturally-aspirated flotation cell (10) to a forced-gas flotation cell without replacing the naturally-aspirated flotation cell reducer (21) with a specialized conversion reducer (103). The adapter (200) is designed to be located below the naturally-aspirated flotation cell reducer (21) and at a location along the drive shaft. The adapter (200) comprises an outer static casing (201) having a forced gas inlet (210); an inner rotating spanner (204) having at least one port (205) therein; sealing means (203, 224, 225, 226) provided between the static casing (201) and the spanner (204); and, a chamber (213) formed between the outer static casing (201) and the spanner (204). Related methods and apparatus incorporating the adapter (200) are further disclosed.
Patent EP-3704385-A1 (EP)
Inventor: RAHIMI DARIUS
IPC: F24F13/24
Filed: 2018-10-30
Abstract: A cover plate 2 for a fan comprises an outer surface 18 and an inner surface 19. The inner surface 19 comprises a tapering projection 12 that projects and narrows away from the outer surface 18. This improves air flow into the fan, reducing cross-currents, eddies and turbulence and making the flow more laminar.
Patent EP-3714007-A1 (EP)
Inventor: READ MARIANNE ROSENBERG
IPC: C08F230/08
Filed: 2018-11-23
Abstract: La présente invention concerne un copolymère comprenant des motifs de répétition de formules (A), (B1) et/ou (B2) et éventuellement (C). Dans la formule (A), R est choisi parmi un H et un alkyle en C 1-6  ; X 1  est choisi parmi COO, CONH et OCO ; m est 0 ou 1 ; R 1  est choisi parmi un alkylène en C 1-8 , linéaire ou ramifié, substitué ou non substitué ; n est 0 ou 1 ; et R 2  est un groupe hétérocyclyle substitué ou non substitué, NR x R y , NHCOR x  ou CONR x R y , R x  et R y  étant indépendamment choisis parmi un alkyle en C 1-8  linéaire ou ramifié, substitué ou non substitué. Dans les formules (B1) et (B2), R est choisi parmi un H et un alkyle en C 1-6  ; X 2  est choisi parmi COOR 3  et OCOR 3  ; o est 0 ou 1; R 3  est choisi parmi un alkylène en C 1-8   linéaire ou ramifié, substitué ou non substitué ; chaque R 4  est indépendamment choisi parmi un alkyle en C 1-10  et un aryle en C 5-10 . Dans la formule (B1), q est un nombre entier compris entre 1 et 160, et dans la formule (B2), q est 0 ou un nombre entier compris entre 1 et 80, R 5  est choisi parmi un alkyle en C 1-10 , un aryle en C 5-10  ou O-Si(R 6 ) 3 , R 6  étant indépendamment choisi parmi un alkyle en C 1-10  et un aryle en C 5-10 . Dans la formule (C), R est choisi parmi un H et un alkyle en C 1-6   ; et X 3  est choisi parmi COOH, COOR 7 , OCOR 7 , OH ou OR 7 , R 7  étant choisi parmi un alkyle en C 1-8  substitué ou non substitué, linéaire ou ramifié. Ledit copolymère comprend de 1 à 40 % en poids de motif de répétition (A), un total de 10 à 90 % en poids de motifs de répétition (B1) et/ou (B2) et de 0 à 70 % en poids de motif de répétition (C).
Patent EP-3720603-A1 (EP)
Title: A microfluidic device and a method for provision of emulsion droplets
Inventor: KVIST THOMAS
IPC: B01F3/08
Filed: 2018-12-04
Abstract: The present invention relates to a microfluidic device and method for providing emulsion droplets. The device comprising: a microfluidic section comprising one or more microfluidic units; and a well section comprising one or more groups of wells comprising one group of wells for each microfluidic unit; the well section and the microfluidic section forming a fixedly connected unit such that each group of wells forms a fixedly connected unit with a respective corresponding microfluidic unit, each microfluidic unit comprising a fluid conduit network comprising: a plurality of supply conduits comprising a secondary supply conduit and a primary supply conduit comprising a capillary structure having a volume of at least 2 µL; a transfer conduit; and a first fluid junction providing fluid communication between the primary supply conduit, the secondary supply conduit, and the transfer conduit; each group of wells comprising a plurality of wells comprising a collection well and one or more supply wells comprising a primary supply well, the collection well being in fluid communication with the transfer conduit of the corresponding microfluidic unit, the primary supply well being in fluid communication with the primary supply conduit and the secondary supply conduit of the corresponding microfluidic unit.
Patent EP-3723741-A1 (EP)
Title: Dissolution d'urate de monosodium pour traiter la goutte
Inventor: HOOPER MARK
IPC: A61K31/60
Filed: 2018-12-14
Abstract: La présente invention concerne un activateur de solubilité pour l'urate de monosodium destiné à être utilisé dans le traitement de la goutte. L'activateur de solubilité peut être une base pharmaceutiquement acceptable, un solvant, un lipide, un tensioactif, un acide pharmaceutiquement acceptable, une cyclodextrine, au moins un parabène ou une combinaison de ceux-ci.
Patent EP-3700564-A1 (EP)
Title: Immunostimulatory compositions
Inventor: ILG THOMAS
IPC: C07H21/00
Filed: 2018-12-07
Abstract: The present disclosure relates to immunostimulatory compositions that are effective in eliciting immune responses in avian species. More specifically, these immunostimulatory compositions comprise an immunomodulator composition and an immunostimulatory oligonucleotide that when administered stimulate toll-like receptor 21.
Patent EP-3727075-A1 (EP)
Title: Insulating device backpack
Inventor: MUNIE JEFFREY CHARLES
IPC: A45F3/04
Filed: 2018-12-17
Abstract: An insulating device can include an aperture having a waterproof closure which allows access to the chamber within the insulating device. The closure can help prevent any fluid leakage into and out of the insulating device if the insulating device is overturned or in any configuration other than upright. The closure may also prevent any fluid from permeating into the chamber if the insulating device is exposed to precipitation, other fluid, or submersed under water. The insulating device may include a back panel support structure and shoulder straps allowing the device to be worn as a backpack. This construction results in an insulating chamber that is substantially impervious to water and other liquids when the closure is sealed.
Patent EP-3669337-A1 (EP)
Title: Apparatus and method for tracing primary and process devices, and closed sterile transfer formulation
Inventor: PY DANIEL
IPC: G08B13/14
Filed: 2018-07-14
Abstract: An apparatus and method for electronically tracing primary devices and process devices, and closed transfer formulation and/or filling the traced primary devices. Each of the primary devices and process devices includes an electronic identifier, such as an RFID tag or barcode. Scanners read the electronic identifiers, and transmit the read identification information to a controller. The controller compares the read identification information to required identification information for a respective product specification, and transmits a signal to further proceed with a formulation or filling process, or not, based on the comparison.
Patent EP-3660486-A1 (EP)
Inventor: HIRONAKA KOJI
IPC: G01N5/02
Filed: 2018-07-25
Abstract: The present invention provides a sensor having excellent sensitivity and selectivity with respect to a ketone-based compound. This sensor according to the present invention has a receiving layer including a polymer having a repeating unit represented by Formula (1), and detects a ketone-based compound.
Patent EP-3665606-A1 (EP)
Inventor: STEINBERG LOUIS
IPC: H04L29/06
Filed: 2018-08-07
Abstract: A set of methods are proposed to increase data security, both in motion and at rest, by creating microshard data fragments. Microshard data fragments are subsets of a data file which are smaller than a defined atomic unit of value (e.g. a fraction of the size of a social security number or valuable password that one seeks to protect). These microshard data fragments are then dispersed across several physical locations, obscuring the value. Additional techniques are proposed to further frustrate unauthorized reassembly attempts and to create system efficiencies.
Patent EP-3667307-A1 (EP)
Inventor: FUJIWARA MASAKI
IPC: G01N27/26
Filed: 2018-08-03
Abstract: The present invention provides a method for accurately measuring a blood component despite uneven distribution of blood introduced into a capillary. The measurement method according to the present invention is characterized in that a plurality of electrode systems for measuring the hematocrit are provided in a capillary of a biosensor to measure the hematocrit at different positions in the capillary. By measuring the hematocrit at the plurality of positions in the capillary as described above, the hematocrit can be measured more accurately despite uneven distribution of blood introduced into the capillary.
Patent EP-3665214-A1 (EP)
Inventor: PEREZ MARIO A
IPC: C08J5/18
Filed: 2018-07-26
Abstract: An oriented film includes, an orientated polyester layer, and alumina particles dispersed within the orientated polyester layer. The alumina particles are present in an amount from 20 to 40% wt of the orientated film. The alumina particles having a D99 value of 25 micrometers or less.
Patent EP-3665930-A1 (EP)
Title: Techniques for non-zero-power beams in wireless systems
Inventor: HAO CHENXI
IPC: H04W24/02
Filed: 2018-08-10
Abstract: Some wireless communication networks may improve communication reliability and/or throughput using multiple-input, multiple-output (MIMO) schemes. MIMO operation may in turn be supported by the use of channel state information reference signals (CSI-RS), which may allow communicating devices to estimate and leverage multipath channel conditions. However, the signaling used to support such communications may consume significant resources. In accordance with the described techniques, a user equipment (UE) may identify non-zero-power beams based on received CSI-RS. The non-zero-power beams may contribute to the final precoding vector. Rather than transmitting beam coefficients relating to zero-power beams, the UE may instead indicate a presence of these zero-power beams to the base station (e.g., by indicating a number of non-zero-power beams). Such techniques may reduce overhead of the communications or otherwise benefit the system.
Patent EP-3662357-A1 (EP)
Title: Display apparatus for providing preview ui and method of controlling display apparatus
Inventor: LEE JI-YEON
IPC: G06F3/0484
Filed: 2018-08-23
Abstract: A display apparatus and a method of controlling the display apparatus are provided. The method includes displaying a first page of a plurality of pages, based on a first touch input being sensed while the first page is displayed, displaying a preview user interface (UI) including a plurality of preview pages respectively corresponding to the plurality of pages, and based on a second touch input being sensed on a preview page among the plurality of preview pages, revising a content included in the preview page on which the second touch input is sensed, according to the second touch input.
Patent EP-3662716-A1 (EP)
Inventor: YUN YEOHUN
IPC: H04W74/00
Filed: 2018-09-07
Abstract: A communication method and system for converging a fifth generation (5G) communication system for supporting higher data rates beyond a fourth generation (4G) system with a technology for internet of things (IoT) includes intelligent services based on the 5G communication technology and the IoT-related technology. A method by a terminal for transmitting uplink data in a wireless communication system comprises receiving downlink control information for scheduling of uplink transmission in a cell from a base station and transmitting the uplink data to the base station on the supplementary uplink if the indicator indicates the scheduling of the uplink transmission is associated with the supplementary uplink in the cell. The downlink control information includes an indicator indicating whether the scheduling of the uplink transmission is associated with a supplementary uplink in the cell.
Patent EP-3685263-A1 (EP)
Title: A method for creating a pre-defined virtual mobilephone profile environment
Inventor: ZACK TZACHI
IPC: H04M1/715
Filed: 2018-09-17
Abstract: System and method for creating a pre-defined virtual mobile phone profile environments in one or more mobile phones, according to which a domain module is generated in a server side which is a computing unit, thereby creating an administrator and a user console. Unique context is generated and uploaded for each domain and managing the context by an administrator and the unique context is stored for each domain on the domain module, which is adapted to store a user- profile data representing at least one set of user-preferences of at least one user and a plurality of entity-profile data of a person of respective entities. An installation file is generating for specific operation system, APK, for each domain, allowing a user to download the installation file into the user mobile phone, to thereby generate a pre- defined second environment, corresponding to the domain. Then a virtual layer is created in a client side by generating a container in the kernel and using operation system tasks and services to simulate a complete second virtual environment.
Patent EP-3668997-A1 (EP)
Title: MiRNA DETARGETING SYSTEM FOR TISSUE SPECIFIC INTERFERENCE
Inventor: HARPER SCOTT QUENTON
IPC: C07H21/02
Filed: 2018-10-02
Abstract: The present disclosure relates to a tissue-specific promoter system for expressing microRNA (miRNA) for RNA interference-based methods of gene therapy. In these systems, the miRNA will inhibit gene expression or replace natural miRNA expression using microRNA.
Patent EP-3692028-A1 (EP)
Title: Inhibiting ubiquitin specific peptidase 30
Inventor: CARAVELLA JUSTIN
IPC: C07D401/06
Filed: 2018-10-05
Abstract: The present disclosure relates to chemical entities useful as inhibitors of Ubiquitin Specific Peptidase 30 (USP30), pharmaceutical compositions comprising the chemical entities, and methods of using the chemical entities. The chemical entities as disclosed herein can be useful in the treatment of a disease, disorder, or condition involving mitochondrial dysfunction, including neurodegenerative diseases, motor neuron diseases, metabolic disorders, and cancers, among other ailments.
Patent EP-3700859-A1 (EP)
Inventor: THOMAS ABHAY V
IPC: C01B32/18
Filed: 2018-10-23
Abstract: A chemically functionalized carbon lattice formed by a process comprising heating a carbon lattice nucleus in a reactor to a temperature between room temperature and 1500C. The process also may comprise exposing the carbon lattice nucleus to carbonaceous gas to adsorb carbon atoms in the carbonaceous gas onto edges of the carbon lattice nucleus, covalently bond the adsorbed carbon atoms to one another in polyatomic rings, a portion of the polyatomic rings comprising non-hexagonal rings, covalently bond the polyatomic rings to one another in one or more new lattice regions extending off the carbon lattice nucleus thereby forming an engineered lattice incorporating the non-hexagonal rings, exposing a portion of the engineered lattice to one or more chemicals to bond at least one of a functional group and molecule to the engineered lattice.
Patent EP-3710936-A1 (EP)
Inventor: BEN-DAYAN MAOR
IPC: G06F11/00
Filed: 2018-10-05
Abstract: A plurality of computing devices are communicatively coupled to each other via a network, and each of the plurality of computing devices is operably coupled to one or more of a plurality of storage devices. One or more of the computing devices and/or the storage devices may be used to rebuild data that may be lost due to a power failure.
Patent EP-3712906-A1 (EP)
Inventor: URASHIMA Kohsuke
IPC: C09D11/52
Filed: 2018-11-13
Abstract: Disclosed is a composition containing copper particles and organic solvents, in which the organic solvents include a first organic solvent having a vapor pressure at 20°C of 200 Pa or more and 20 kPa or less, and a second organic solvent having a vapor pressure at 20°C of 0.5 Pa or more and less than 200 Pa.
Patent EP-3723022-A1 (EP)
Title: Tire-rental management device and tire-rental management method
Inventor: WATANABE JUN
IPC: G06K7/10
Filed: 2018-09-12
Abstract: A tire rental management apparatus according to the present disclosure includes an input interface configured to accept input of a usage area and/or a usage period of a tire as a condition regarding rental of the tire to a user, and a controller configured to determine a tire in accordance with the usage area and/or the usage period input to the input interface as a rental tire among a plurality of tires for rental.
Patent EP-3728300-A1 (EP)
Title: Targeting mitochondrial fission through mdivi-1 derivatives
Inventor: LISANTI MICHAEL P
IPC: C07K7/06
Filed: 2018-12-18
Abstract: Derivatives of mDIVI-1 may be used to target and eliminate cancer stem cells. Disruption in the mitochondrial dynamics balance plays a role in cancer. Proteins involved in regulating mitochondrial dynamics represent potential targets for cancer treatment. Mitochondrial fission protein DRPl is such a target. Derivatives of mDIVI-1 inhibit DRPl, and have demonstrated inhibition of tumorsphere forming capacity, migration and sternness-related signaling in breast cancer cells. These properties result from induction of mitochondrial oxidative stress and reduction of mitochondrial metabolism in the target cancer cells. The potency of an mDIVI-1 derivative may be dramatically increased through addition of at least one membrane-targeting signal and/or a mitochondria-targeting signal.