baber/WOPTO huggingface dataset:
Patent NZ-551253-A (NZ)
Title: Pyridin-4-yl-ethynyl-imidazoles and pyrazoles as MGLU5 receptor antagonists
Inventor: BUETTELMANN BERND
IPC: A61K31/444
Filed: 2005-05-23
Abstract: A process for making a substituted indole derivative of formula (I) is disclosed, wherein said process comprises: reacting a substituted indole compound of formula (I') with a heteroaryl or aryl zinc halide or di-heteroaryl or di-aryl zinc compound as defined in the specification, wherein the variables are as defined in the specification, and wherein the reaction is carried out in the presence of a metal catalyst selected from Pd and Ni, a ligand selected from mono-dentate triphenylphosphine (Ph3P), tri-p-tolylphosphine (p-Tol3P), tricyclohexylphosphine (PCy3), tri-t-butylphosphine (t-Bu3P), (Cy2P(Ph-Ph)) and bi-dentate 1,1'-bis(diphenylphosphino)ferrocene (dppf), 1,4-bis(diphenylphosphino)ferrocene (dppb), in a solvent selected from tetrahydrofuran (THF), dimethoxyethane (DME), dimethylformamide (DMF), 1-methyl-2-pyrrolidinone (NMP) or a combination thereof, at a temperature of between ambient and 100 Deg. C, to provide the desired compound of formula (I).
Patent NZ-553174-A (NZ)
Title: Methods of using death receptor ligands Apo2L/Trail and CD20 antibodies
Inventor: ASHKENAZI AVI J
IPC: A61K39/395
Filed: 2005-09-07
Abstract: Disclosed is a use of a synergistic effective amount of Apo2L/TRAIL polypeptide and CD20 antibody, in the manufacture of a medicament for treating cancer cells and immune related diseases.
Patent NZ-554276-A (NZ)
Title: Paper or cardboard fire resistant barrier for light fittings
Inventor: GOW BRENDAN DARREN
Filed: 2007-04-02
Abstract: A fire resistant barrier forms an enclosure to be mounted in a ceiling space to surround a light fitting 18 mounted in the ceiling. The enclosure is formed by a box with walls 17 and a top lid 23 of fire retardant paper or cardboard material, and ventilation slits 22 to allow heated air to ventilate from the inside of the enclosure. The barrier prevents inflammable materials coming into contact with the hot light fitting.
Patent NZ-554347-A (NZ)
Title: Use of agomelatine in obtaining medicaments intended for the treatment of generalized anxiety disorder
Inventor: DELALLEAU BRUNO
Filed: 2007-04-05
Abstract: Use of agomelatine, or N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide, or its hydrates, crystalline forms and addition salts with a pharmaceutically acceptable acid or base, in obtaining a medicament intended for the treatment of Generalized Anxiety Disorder is disclosed. The crystalline II form of agomelatine is particularly suitable for the treatment of Generalized Anxiety Disorder.
Patent NZ-575730-A (NZ)
Title: A toilet comprising a valve with a cartridge unit having pivotable gate for controlling a flow from a toilet bowl to a trap way
Inventor: KOPPLIN CHARLES R
IPC: E03D11/10
Filed: 2007-09-13
Abstract: Disclosed is a toilet (20) comprising a bowl (22), a trap (26) and a valve. A bowl (22) has a discharge outlet (24). A trap (26) is in fluid communication with the discharge outlet (24). The valve is positioned to control outflow from the discharge outlet (24) to the trap (26). The valve comprises a cartridge unit (28) having a first housing part (36) and a second housing part. The second housing part is linked to the first housing part (36) to define a cavity. The cartridge unit (28) has an inlet at one end of the cavity and outlet at the other end of the cavity. The cartridge unit (28) inlet is detachable to the bowl discharge outlet (24) and to the trap (26). There is a pivotable gate (40) positioned in the cavity so as to be movable between a first position to a second position. In the first position, the gate (40) essentially closes off the flow through the discharge outlet (24).In the second position, the flow is permitted from the discharge outlet (24) to the trap (26). The gate (40) has an outer contour (46) on a side of the pivotable gate (40) opposite the inlet of the cartridge unit (28). The cavity has a recess along one of its walls. The recess has an inner contour that is essentially complementary in shape with the outer contour (46) of the gate (40). When the gate (40) is in the second position, the outer contour (46) of the gate (40) is positioned adjacent the inner contour. The valve cartridge (28) provides a flow path that bends from an essentially vertical path adjacent the bowl discharge outlet (24) to a path that is at least somewhat horizontal.
Patent NZ-577427-A (NZ)
Title: Method for producing potato products using debranching enzymes pullulanase and isoamylase
Inventor: KALUM LISBETH
IPC: A23L19/12
Filed: 2008-01-16
Abstract: Disclosed is a method for increasing the content of resistant starch in a potato product using one or more debranching enzymes selected from pullulanase and isoamylase at a temperature suitable for enzymatic treatment and holding the enzyme treated potato at a temperature of between -2 and 50 degrees Celcius.
Patent NZ-578256-A (NZ)
Title: Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
Inventor: JONES PHILIP
IPC: A61P29/00
Filed: 2008-01-08
Abstract: Disclosed is a compound of formula (I), wherein the substituents are as defined in the specification. The compounds are amide substituted indazoles and are inhibitors of poly (ADP-ribose) polymerase useful in the treatment of cancer, inflammatory diseases, reperfusion injuries, ischemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes, neurodegenerative diseases, retroviral infection, retinal damage or skin senescence and UV-induced skin damage.
Patent NZ-581394-A (NZ)
Title: A thin cast strip product with microalloy additions, and method for making the same
Inventor: WILLIAMS JAMES GEOFFERY
IPC: B22D11/06
Filed: 2008-05-06
Abstract: Disclosed is an age hardened steel product comprising, carbon, manganese, silicon, and aluminum, at least one element from the group consisting of niobium or vanadium and having a majority of the microstructure comprised of bainite and acicular ferrite and having an increase in elongation and an increase in yield strength after age hardening. Also disclosed is a method of preparing the above steel product comprising: assembling internally a cooled roll caster having laterally positioned casting rolls forming a nip between them, and forming a casting pool of molten steel supported on the casting rolls above the nip and confined adjacent the ends of the casting rolls by side darns, counter rotating the casting rolls to solidify metal shells on the casting rolls as the casting rolls move through the casting pool, and forming steel strip from the metal shells cast downwardly through the nip between the casting rolls, and cooling the steel strip and further age hardening the steel strip at a temperature between 625 degrees Celsius and 800 degrees Celsius.
Patent NZ-586447-A (NZ)
Title: Method for producing vanadium products by fluidization technique
Inventor: PENG YI
IPC: C22B3/08
Filed: 2008-10-21
Abstract: A method for producing vanadium products by a fluidization technique is disclosed, wherein the method comprises the following steps:(a) preparing for high-calcium vanadium slags having CaO/V2O5 weight ratio not less than 0.5 but not more than 0.7; (b) roasting the high-calcium vanadium slags in a fluidized bed furnace to obtain roasted clinker (wherein the mean temperature in the fluidized bed furnace is around 850 Deg C to 950 Deg C, and the mean residence time of the vanadium slags in the fluidized bed furnace is 30min-150min); and (c) leaching the roasted clinker in sulfuric acid solution, and further preparing the vanadium products from leach liquor. Another method for producing vanadium products by a fluidization technique is also disclosed, wherein step (a) involves preparing for high-calcium vanadium slags having CaO/V2O5 weight ratio more than 0.7 but not more than 1.4, followed by the steps of roasting, leaching and preparing the vanadium products.
Patent NZ-587862-A (NZ)
Title: Detachable ladder attachment device with multiple hooks wedged between two rungs of a ladder
Inventor: HEAVEN DARRYLL
IPC: E06C1/36
Filed: 2010-09-09
Abstract: A ladder attachment (1) in combination with a ladder (8) is disclosed. The attachment (1) has a first hook (3) and a second hook (4). The first hook (3) is engaged with a rung of the ladder (8) and the second hook (4) is hooked onto roof guttering or to a solid object. The attachment (1) is releasably wedged between two rungs of the ladder in such a way that in the event that the ladder (8) begins to move when in use with a human on it in an elevated position, the ladder (8) is prevented from tipping over.
Patent NZ-588153-A (NZ)
Title: Fungicide composition for agriculture and horticulture and method for preventing plant diseases
Inventor: MITANI SHIGERU
IPC: A01P3/00
Filed: 2009-03-27
Abstract: Disclosed is a fungicide composition comprising an imidazole compound of general formula (I) and a polyoxin. Also disclosed is a method for controlling a plant disease, comprising applying the fungicide composition to a plant.
Patent NZ-592171-A (NZ)
Title: Method for manufacturing a wind turbine rotor blade by forming composite material around two moulding cores and after the blade has set removing the cores through openings in the blade
Inventor: STIESDAL HENRIK
IPC: F03D1/06
Filed: 2011-04-08
Abstract: A method for manufacturing a wind turbine rotor blade 1 is described. Composite material is placed around a moulding core arrangement. The moulding core arrangement includes a first moulding core 23 and a second moulding core 26. The composite material is set forming a wind turbine rotor blade 1. The wind turbine rotor blade 1 includes a root portion 3 at a root end, a tip 2, a leading edge 9, and a trailing edge 11. The trailing edge 11 has a shoulder 4 where the chord length between the leading edge 9 and the trailing edge 11 is maximum, and a shoulder portion 4 extending between the root end and a point on the trailing edge between the shoulder and the tip where the chord length between the leading edge and the trailing edge is 70% of the maximum chord length. The first moulding core 23 is removed from the wind turbine rotor blade 1 through an opening 31 at the root portion 3. The second moulding core 26 is removed from the wind turbine rotor blade 1 through an opening 33 at the shoulder portion 4.
Patent NZ-592297-A (NZ)
Title: 2-Aryl-5-heteroaryl pyridine and pyrimidine derivatives as pharmaceutical active agents
Inventor: ENDRES GREGORY W
IPC: A61K31/167
Filed: 2009-09-22
Abstract: Disclosed are 2-aryl-5-heteroaryl pyridine and pyrimidine derivatives as represented by the general formula (I), wherein R1 is alkyl, cycloalkyl, phenyl, 2-pyridyl, 3-pyridyl, or 4-pyridyl; wherein each phenyl, 2-pyridyl, 3-pyridyl, or 4-pyridyl of R1 may be optionally substituted with no more than two of each or a combination of fluoro, hydroxy, -CH2OH, carboxy, carboxymethyl, or carboxyethyl; W is a covalent bond, O, S, SO, SO2, CH2, CHOH, or CO; Each of U1-U4 is selected from N-R6, O, or S, CR6 or N; and wherein the remaining substituents are as defined herein. Representative compounds include 2-(3-fluorophenyl)-4-(2-phenylpyrimidin-5-yl)thiazole, 4-(2-phenylpyrimidin-5-yl)-2-(pyridin-3-yl)thiazole, ethyl 5-(2-phenoxypyrimidin-5-yl)-1H-pyrazole-3-carboxylate, 2-phenyl-5-(2-phenylpyrimidin-5-yl)oxazole, 2-phenoxy-5-(2-(pyridin-3-yl)-1H-imidazol-4-yl)pyrimidine, 2-phenyl-5-(2-phenyl-1H-imidazol-5-yl)pyrimidine. Further disclosed is a pharmaceutical composition which comprises a compound as defined above or a pharmaceutically acceptable salt thereof for treating a disease or condition mediated at least in part by prostaglandin D2 produced by H-PGDS, such as allergic inflammation, asthma or Duchenne muscular dystrophy.
Patent NZ-594181-A (NZ)
Title: Fungicidal pyrazoles
Inventor: LONG JEFFREY KEITH
IPC: A61K31/4155
Filed: 2010-03-03
Abstract: 594181 Disclosed herein is a compound of Formula I or Formula 2, wherein the variables are defined in the specification, and the use thereof as fungicides. Embodiments of the compound include: N-(4-chlorophenyl)-4-(2,6-difluoro-4-methoxyphenyl)-1,3-dimethyl-1H-pyrazol-5-amine, 4-[[4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-yl]oxy]-3,5-difluorobenzonitrile, 4-(2-chloro-4-fluorophenyl)-?-(2,4-difluorophenyl)-1,3-dimethyl-1H-pyrazole-5-methanol, and 4-(2,6-difluoro-4-methoxyphenyl)-1,3-dimethyl-N-(2,4,6-trifluorophenyl)-1H-pyrazol-5-amine.
Patent NZ-594596-A (NZ)
Title: All natural multivitamin and multimineral dietary supplement formulations for enhanced absorption and biological utilization
Inventor: SINNOTT ROBERT A
IPC: A23L33/15
Filed: 2006-10-26
Abstract: Disclosed is a dietary supplement formulation and a method to prepare it comprising a first standardized plant extract comprising plant-derived zinc, wherein the plant derived zinc is in or about cellular structures and the standardized source of plant-derived zinc is standardized for zinc; a second standardized plant extract comprising one or more natural vitamins or provitamins selected from vitamin A, beta-carotene, carotenoids, lycopene, lutein, zeaxanthin, cryptoxanthin, thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B1), folate (vitamin B9), cyanocobalamin (vitamin B12), vitamin C-complex, vitamin D, vitamin E, tocopherols, tocotrieneols, and one or more additional nutrients selected from the group consisting of vitamin D, vitamin C, calcium, magnesium, strontium, and boron, wherein the plant-derived minerals are selected from the group consisting of seedlings of Brassica napus, Brassica rapa, Brassica juncea,Medicago sativa, and Oryzae sativa seeds, wherein the supplement is compressed at a pressure greater than 2,000 psi for enhanced vitamin absorption by suppression of intestinal glucuronidation.
Patent NZ-599334-A (NZ)
Title: Synthetic methods for spiro-oxindole compounds
Inventor: CHOWDHURY SULTAN
IPC: C07D491/20
Filed: 2010-10-14
Abstract: 599334 Disclosed herein are methods of preparing certain spiro-oxindole derivatives, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. In one embodiment a compound of formula (I) is prepared by treating spiro[furo[2,3-f][1,3]benzodioxole-7,3’-indol]-2’(1’H)-one with 2-bromomethyl-5-(trifluoromethyl)furan. In another embodiment a compound of formula (II) is prepared by treating 2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3’-indol]-2’(1’H)-one with 2-(chloromethyl)-3-(trifluoromethyl)pyridine hydrochloride.
Patent NZ-599862-A (NZ)
Title: Vapor recovery pump regulation of pressure to maintain air to liquid ratio
Inventor: DALZIEL LINDSAY BRUCE
IPC: B67D7/02
Filed: 2010-10-19
Abstract: 599862 A vapour recovery system recovers vapours expelled from a vehicle during refuelling at a fuel dispensing point and returns the vapours to an underground storage tank through a vapour flow path that is in fluid communication with an air to liquid regulator valve and a vapour pump. The air to liquid regulator valve (500) regulates the amount of vapour that is recovered through the fuel dispensing point in proportion to the fuel dispensed into the vehicle, and a controller (270) monitors a parameter of the vapour recovery system such as, for example, the pressure within a first portion of the vapour flow path (220) between the inlet side of the vapour pump (250) and the air to liquid regulator valve, and maintains a substantially constant pressure level in the first portion of the vapour flow path. As the amount of fuel that is dispensed by the fuel nozzle (210) increases, the amount of vapour laden air that is drawn into the combined inlet portion of the vapour return passages by the vapour pump increases. This increased load on the vapour pump causes the vapour pump to begin to slow down as more torque is required but the current supplied to the motor (252) remains constant. In response to the reduction in speed, the control system increases the amount of current provided to the motor, thereby increasing the amount of torque that is produced. As such, the vapour pump is able to maintain the desired vacuum level within the combined inlet portion of the vapour return passages even though the amount of vapour being drawn through the vapour pump has increased. The control system similarly reduces the amount of current that is supplied to the motor when the load on the vapour pump is reduced.
Patent NZ-600730-A (NZ)
Title: A support tray and pipe support
Inventor: GRAY JEREMY
IPC: F16L59/135
Filed: 2012-06-19
Abstract: 600730 A support assembly typically for pipes has a load support member 4.032, 5.032, 6.032 that has side flanges. At least one and typically two support members 5.002, 5.003 have legs and at least one of these has a re-entrant hook formation with which in use the load support member flanges engage with the non-free end of each flange being pressed against the other leg of the support member. Other embodiments are disclosed.
Patent NZ-600936-A (NZ)
Title: Method and apparatus for detecting and treating heart failure
Inventor: SCHINDHELM KLAUS HENRY
IPC: A61B5/02
Filed: 2009-07-24
Abstract: 600936 Apparatus disclosed has a monitor to evaluate heart failure using sensing of respiration and treatment pressure and determining a parameter based on apnea/hypopnea or apnea counts, and then generating a heart failure change condition of a patient.
Patent NZ-601289-A (NZ)
Title: Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
Inventor: CHEN ROGER SHEN-CHU
IPC: C07D495/04
Filed: 2011-02-10
Abstract: Disclosed herein is a compound of formula (I), wherein the variables are defined in the specification, and the use thereof in the treatment of cancer, a disorder associated with angiogenesis, pain, macular degeneration or a related syndrome, a skin disease, a pulmonary disorder, an asbestos-related disorder, a parasitic disease, an immunodeficiency disorder, a CNS disorder, CNS injury, atherosclerosis or a related disorder, dysfunctional sleep or a related disorder, an infectious disease, hemoglobinopathy or a related disorder or a TNFα related disorder. In one embodiment the compound is 3-(4-(4-(2-morpholinoethoxy)-benzyloxy)-1-oxoisoindolin-2-yl)-piperidine-2,6-dione.
Patent NZ-603129-A (NZ)
Title: Solubilization of carbonaceous materials and conversion to hydrocarbons and other useful products
Inventor: DOWNEY ROBERT A
IPC: C09K8/58
Filed: 2011-04-21
Abstract: 603129 Methods of producing useful products, such as hydrocarbons and other molecules that are useful as fuels, from carbonaceous materials, are disclosed. Such methods include obtaining a carbonaceous material, such as coal, from a deposit and treating the carbonaceous material with one or more with one or more esters of acetic acid, alone or in combination, to solubilize the material in preparation for further processing, such as bioconversion, to produce useful products, or solubilizing the carbonaceous material in a formation using the above-recited chemicals, removing the solubilized material from the formation and bioconverting it to produce useful products, or solubilizing the material using the above-recited chemicals and bioconverting at least a portion of the solubilized material in a formation followed by recovery of useful products from the formation. Wherein the ester of acetic acid is selected from the group consisting of methyl acetate, ethyl acetate, propyl acetate, isopropyl acetate, n-butyl acetate, isobutyl acetate, amyl acetate, isoamyl acetate, hexyl acetate, heptyl acetate, octyl acetate, nonanyl acetate, decyl acetate, undecyl acetate, lauryl acetate, tridecyl acetate, myristyl acetate, pentadecyl acetate, cetyl acetate, heptadecyl acetate, stearyl acetate, behenyl acetate, hexacosyl acetate, triacontyl acetate, benzyl acetate, bornyl acetate, isobornyl acetate and cyclohexyl acetate.
Patent NZ-604007-A (NZ)
Title: Monoclonal antibodies against her2 epitope
Inventor: BRINK EDWARD N VAN DEN
IPC: C07K16/32
Filed: 2011-05-27
Abstract: Disclosed is a monoclonal antibody which binds to the same epitope on epidermal growth factor receptor 2 (HER2) as a reference antibody, the monoclonal antibody comprising the VH and VL regions selected from the group consisting of the VH and VL sequences as disclosed in the specification. Also disclosed is the use of the antibody for the manufacture of a medicament for the treatment of cancer.
Patent NZ-609567-A (NZ)
Title: Markers of endothelial progenitor cells and uses thereof
Inventor: BONDER CLAUDINE SHARON
IPC: G01N33/53
Filed: 2011-11-07
Abstract: Disclosed is a composition comprising a population of cells enriched for non-adherent endothelial progenitor cells (EPCs) expressing a nucleic acid or protein selected individually or collectively from DSG2 and EMR2. Also disclosed is the use of an antibody or antigen binding fragment thereof that specifically binds to DSG2 and/or EMR2 or an immunogenic fragment or epitope thereof in the manufacture of a medicament for localising and/or detecting non-adherent EPCs in vivo. Further disclosed is an ex vivo method for detecting a non-adherent endothelial progenitor cell (EPC) comprising determining the level of expression of a nucleic acid or protein selected individually or collectively from DSG2 and EMR2 in, on or secreted from a cell, wherein an increased level of expression of a nucleic acid or protein selected individually or collectively from DSG2 and EMR2compared to another cell type is indicative of a non-adherent EPC.
Patent NZ-620174-A (NZ)
Title: Protein kinase conjugates and inhibitors
Inventor: QIAO LIXIN
IPC: G01N33/53
Filed: 2010-09-15
Abstract: Disclosed is a protein kinase conjugate that has the formula, X-M-S-CH2-Prot wherein, Prot is a protein kinase or portion thereof that contains a cysteine residue selected from the group consisting of CYS1, CYS5, CYS6, CYS7, CYS8, CYS9, CYS10, CYS11, CYS12 and CYS13; S-CH2 is the sulfur atom and methylene group from the side chain of said cysteine residue; M is a modifier moiety that is formed by the covalent bonding of a warhead group with the side chain of said cysteine residue; and X is a chemical moiety that binds in or near the ATP binding site of the protein kinase. Also disclosed in the use of the conjugates in the manufacture of a medicament for topical treatment of diseases and conditions, especially of the eye.
Patent NZ-628194-A (NZ)
Title: A feed apparatus and system
Inventor: BEN STANLEY NEAL
IPC: A01K5/02
Filed: 2014-08-01
Abstract: Disclosed is a liquid feeding systems, typically being milk or milk powder mixed on site and fed to calves, with a common supply line for individual stalls along its length.
Patent NZ-701544-A (NZ)
Title: Thermal cycling apparatus and method
Inventor: DORITY DOUG
IPC: F25D1/00
Filed: 2013-05-15
Abstract: A thermal cycling apparatus for a biological testing apparatus. The thermal cycling apparatus can have a sample interfacing wall extending from a mounting wall. The sample interfacing wall can accept and apply thermal cycles to samples. An air source can direct an air stream to cool the sample. Another source can direct heated air away from the sample.
Patent NZ-704103-A (NZ)
Title: Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates
Inventor: ZHU YUANMING
IPC: C07D213/803
Filed: 2013-07-23
Abstract: Provided herein are processes for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates comprising a step of converting chloropicolinoyl chlorides to fluoropicolinoyl fluorides.