baber/WOPTO huggingface dataset:
Patent CZ-289252-B6 (CZ)
Title: 7-(Substituted)-8-(substituted)-9-/(substituted glycyl)amido/-6-demethyl-6-deoxytetracyclines, processes of their preparations and pharmaceutical and veterinary preparations based thereon
Inventor: SUM PHAIK-ENG
IPC: C07C/
Filed: 1993-08-06
Abstract: In the present invention there are disclosed 7-(substituted)-8-(substituted)-9-/(substituted glycyl)amido/-6-demethyl-6-deoxytetracyclines of the general formula I, wherein X is halogen; R is selected from hydrogen or -NRe1Re2 wherein Re1 and Re2 each represent alkyl containing 1 to 3 carbon atoms; Re3 and Re4 each represent hydrogen; and W represents a monosubstituted alkylamino group having 1 to 6 carbon atoms, a mono[(cycloalkyl)alkyl]amino group containing 3 to 6 carbon atoms in the cycloalkyl moiety and 1 to 3 carbon atoms in the alkyl moiety; dialkylamino containing 2 to 6 carbon atoms, or a halogen; as well as their pharmaceutically acceptable salts with organic or inorganic acids. The present invention also relates to a process for preparing tetracyclines of the general formula I, wherein W does not represent halogen, the process comprising treating the corresponding compound of the general formula I, wherein W represents a halogen with the nucleophilic compound W'H, wherein W' represents W except for halogen. In the present invention there is also claimed a process for preparing tetracyclines of the general formula I, which process is characterized in that when preparing compounds in which W is halogen the corresponding compound of the general formula X is treated with a corresponding  haloacyl halide (Re3, Re4, Y)C C(=O)Q wherein Y and Q each represent halogen or when preparing all compounds of the general formula I the compound of the general formula X is treated with a corresponding chloride of the formula (Re3, Re4, W)C C(=O)X, wherein X is halogen. The invention also describes the use of the tetracyclines of the general formula I for the prevention, treatment or control of bacterial infections in warm-blooded inclusive of infections caused by bacteria having the TetM and TetK resistant determinants. Corresponding pharmaceutical and veterinary preparations, based on the above-indicated compounds, form an integral part of the present invention, too.
Patent CZ-309183-B6 (CZ)
Title: Method for safely flushing water network pipes and mobile device for safely flushing water network pipes
Inventor: RAJNOCHOVÁ MARKÉTA
IPC: G05D7/06
Filed: 2021-02-02
Abstract: The mobile device consists of an inlet flange (1) with an adapter (2) for connecting the water supply leading from the hydrant of the water supply network, a calming pipe (3) connected at one end to the inlet flange (1), at least one electrical meter or a quality parameter of the water connected to the calming pipe (3), from a safety valve (4) arranged at the other end of the calming pipe (3), from the electric flow meter (5) behind the safety valve (4) in the direction of water flow, from the electrically operated slide (6) behind the electric flow meter (5) in the direction of water flow, from the outlet flange (7) with an adapter (2) arranged to an electrically operated slide (6) for connecting a water drain from a mobile device. It further consists of at least one control device for controlling the operation of the mobile device and an electronic control unit (8) which is wired or wirelessly connected to at least one water physical or quality meter, to an electric flow meter (5), to an electrically operated slide (6) and to the control device.The method consists of continuously during the flushing the instantaneous water pressure in the pipeline is continuously compared with the permissible pressure limits until the end of flushing, while when the trend of instantaneous pressure changes outside the set limits is detected set limits.
Patent CZ-309850-B6 (CZ)
Title: A method of reducing the deformation of the working shaft and an assembly for its implementation
Inventor: Valášek Michael
IPC: F16F15/02
Filed: 2022-01-13
Abstract: A method of reducing the deformation of a working shaft of the shaft, wherein the working shaft (1) is connected to at least one auxiliary shaft (2), sensors (6, 7, 8, 91, 92) measure the position or movement of the working shaft (1) and, based on the signals from these sensors, a force effect from the auxiliary shaft (2) to the working shaft (1) acting against the force load (12) is derived by the sliding actuator (3) or the rotary drive (17). In the assembly of the working shaft and at least one auxiliary shaft, the working shaft (1) and the auxiliary shaft (2) are supported by means of at least one inner bearing (10) or outer bearing (4). The working shaft (1) is connected to the auxiliary shaft (2) by at least one internal bearing (10) or cogwheel (13). In at least one inner bearing (10) and/or at least one outer bearing (4) and/or on the frame (5), the control elements of the actuator (3) or the drive (17) are arranged to exert a force or moment acting against the force load (12) on the working shaft (1).
Patent CZ-290094-B6 (CZ)
Title: Food mixture, process of its preparation and process for preparing cation salt of pectin
Inventor: GLAHN POUL-EGEDE
IPC: A23L29/231
Filed: 1994-12-02
Abstract: The invented food mixture contains a food in connection with a cation salt of pectin. The mixture, when suspended in distilled water, will swell to heat stable particles having a mean equivalent diameter greater than 100 micrometers. When preparing the invented food mixture the food is mixed with a dry cation salt of pectin, which, when suspended in distilled water, will swell to heat stable particles having a mean equivalent diameter greater than 100 micrometers. Process for preparing the cation salt of pectin for the invented food mixture is characterized in that a starting pectin material is treated with a solution of a cation salt having concentration of at least 5mM/liter under non-shear conditions and at a pH value being at least 2, under formation of a reaction mixture containing large gel particles that are visible with the naked eye.
Patent CZ-284947-B6 (CZ)
Title: Apparatus for stacking slices of articles
Inventor: MELI VINCENT A
IPC: B65B51/26
Filed: 1992-05-11
Abstract: Food item (10) formed into soft mass is packaged to form individually wrapped slices by V-folding continuous web (12) of heat sealable thermoplastic as it is advanced to form front and rear sheets, hermetically sealing the open longitudinal side of the web to form a continuous tubular web, inserting the food item into the tubular web, flattening the web to form a continuous slice of the food item between the top and bottom layers of web, and forming hermetic cross-seals across the web at predetermined intervals as it is continuously advanced. The web is cooled after it is flattened before the cross-seals are formed. Pref. the hermetic cross seals are formed using a pair of endless chains (42,44) on which sealing members are disposed, the chains having aligned runs along which the sealing members ride in aligned relationship for a fixed distance and between which the flattened web is introduced. Heat is applied to at least one sealing member of each pair and pressure is applied to them to urge the upper and lower layers of the web together, the applied heat being sufficient to cause permanent sealing.
Patent CZ-295114-B6 (CZ)
Title: Microcapsules containing suspensions of biologically active compounds and ultraviolet protectant as well as process for preparing such microcapsules
Inventor: SCHER HERBERT BENSON
IPC: A01N25/30
Filed: 1996-04-18
Abstract: In the present invention, there are disclosed Microcapsules containing 0.1 percent by weight to 55 percent by weight of a biologically active material that which is sensitive to ultraviolet light and an effective amount of an ultraviolet light protectant, which protectant is selected from the group consisting of titanium dioxide, zinc oxide and mixtures thereof are prepared which contain an ultraviolet light protectant selected from titanium dioxide, zinc oxide and mixtures thereof wherein both these components are suspended and thoroughly dispersed in an organic liquid that is immiscible with water and that is sufficiently polar to dissolve a prepolymer used for forming microcapsule walls. Described is also a process for preparing such microcapsules.
Patent CZ-293351-B6 (CZ)
Title: 5-Membered heterocyclic compounds as inhibitors of leucocyte adhesion and VLA-4 antagonists, and pharmaceutical composition containing thereof
Inventor: STILZ HANS ULRICH DR
IPC: C07K5/023
Filed: 1997-11-13
Abstract: In the present invention, there are disclosed compounds of the general formula I, in which the symbols B, D, E, R, W, Y, Z, b, c, d, e, f, g and h have specific meanings. These compounds are inhibitors of adhesion and migration of leukocytes and/or antagonists of VLA-4 adhesion receptor, which pertains to the group of integrins. Described is also the use of the compounds of the general formula I for preparing medicaments intended for treating or prophylaxis of diseases caused by undesired extent of leukocyte adhesion and/or migration or in which the cell-cell or cell-matrix interaction play a role, which are based on   interaction of VLA-4 receptors with ligands thereof, such as inflammatory processes, rheumatic arthritis or allergic diseases. Further described are novel compounds of the general formula I per se as well as pharmaceutical compositions in which the novel compounds are comprised.
Patent SK-277732-B6 (SK)
Title: Method of mat manufacturing or product of similar form from ceramic, glass or mineral fibers or from their mixture and the device for realization of this method
Inventor: NIEMINEN JORMA
IPC: B28B1/52
Filed: 1989-02-15
Abstract: Fibers are lead into contact with air flow, which transfer and put them in the shape of homogeneous fiber fleece in the first transport plane from which they are transported to the opposite transport plane by air flow passing through the first transport plane whereby the occasional oriented fibers are settled and create the fiber fleece, which is submitted to the eventual next treatment for binding of fibers. Device containing the mechanism for layering of fibers to form a mat or product of similar form, has in its mechanism (D) for forming of fiber fleece two perforated conveyers (32,33) letting through the air and creating the first transport plane for fiber materials and over the second perforated conveyer (33) it has the third perforated conveyer (36) letting through the air and creating the second transport plane, between point (34) of the second perforated conveyer (33) and third perforated conveyer (36) has created the free space (37), inside of this free space (37) is the guide channel (41) for air supply into the free space through the openings of the second perforated conveyer (33) and over the location (34) of the second perforated conveyer (33) is the air flow output channel (38) located on the opposite side of free space (37) and opened from the side of transport plane of third perforated conveyer (36).
Patent SK-278204-B6 (SK)
Title: Metal expanding anchor and manufacturing process thereof
Inventor: HENGESBACH WOLFGANG
IPC: F16B13/06
Filed: 1993-11-17
Abstract: Expanding anchor consists of a shank (1) with a threaded section (2) on its rear part for fast fixing of an object. In the front part of the shank (1) there is stepped section (3) which passes, toward the front end, into the expanding cone (4). In the stepped section area (3) an expanding sleeve (5) is putted on. The expanding anchor is anchored in a bored hole of a concrete block. When the shank (1) of the expanding anchor is axially shifted, the expanding cone (4) is dragged into the expanding sleeve (5) firmly deposited in the bored hole through fixing elements (7). Fixing elements (7) are triangular shaped pressings. Metallic expanding anchor is produced as follows: flat expanding sleeve /5/ is pressed out with a small underdimensioning of size and then the thickness of the sheet is clamped through pressing. After clamping the fixing elements are stamped.
Patent SK-278660-B6 (SK)
Title: Synthetic zeolite and preparation method thereof
Inventor: POCHEN CHU
IPC: C01B39/00
Filed: 1990-05-25
Abstract: This patent is dealing with synthetic zeolite, a character of which is seen based on the X-ray diagram, represented by the values described in the table I and this zeolite is prepared based on the reaction mixture containing YO2/X2O3 = 10 up to 80, H20/YO2 = 5 up to 100, OH/YO2 = 0,01 up to 1,0 M/YO2 = 0,01 up to 2,0, R/YO2=0,05 up to 1,0, while these measures are expressed in molar ratio, and where R means hexamethylenimine and M alkaline metal or metal closed to alkaline earth, where the resource of Y oxide contains minimum 30 weight percent of the solid YO2 and this reaction mixture is being kept at the temperature of 80 up to 300 Celsius degrees, for 24 hours up to 60 days, until the crystals closed to the above mentioned material are not created.
Patent SK-278682-B6 (SK)
Title: Manufacturing process of the singly- or doubly-curved laminated sheet glass, particularly for motor vehicles
Inventor: TUNKER GERHARD
IPC: B32B17/10
Filed: 1992-09-29
Abstract: The procedure described in this patent is related to the production of the table which consists of the internal glass table, external glass table and of the intermediate layer made based on the plastic material. Squeegee enamel colour is used and this colour consists of a glass binder, of at least one ceramic pigment and silicon binder and this mixture is mixed with organic squeegee oil. This printed matter is coated by enamel colour to the assigned surface part of the table with the use of squeegee. This printed matter is being dried at the temperature enabling evaporation of oil. Both of the tables with the dried printed matter are placed on each other, they are heated to the temperature, at which the shaping is possible and they are bent in pairs according to single or double curvature, while the printed matter is fired simultaneously. The bent table pairs are being separated of each other, the plastic foil is inserted in between and the table pairs are placed on each other, after the above mentioned foil is removed, they are heated and connected, while the glass table with layers is created.
Patent SK-279605-B6 (SK)
Title: Process and plant for producing heat-treated growth substrate and manure
Inventor: CLAUSEN HANS J
IPC: C02F11/13
Filed: 1990-08-13
Abstract: In natural substrate or fertilizer materials such as sphagnum, coir dust or poultry manure seeds and other impurities can occur which can be neutralized by heat treatment. Heat treatment is effectively commenced in a kiln (8), which is interconnected with a station (10), and is led further to a heat insulated tunnel (38) wherein the period of heat treatment can be prolonged essentially without additional energy consumption, and the material flow is led through a transportation system substantially closed in relation to the surroundings, and which comprises a cooling zone (42), in which the material is cooled by blow-through with filtrated air, an admixing station (12) in which desired fertilizer substances and microbiological matter are added to the material flow, and a delivery zone or station (16), in which the material is dosed to closed transportation containers, e.g. closed sacks.
Patent CZ-296986-B6 (CZ)
Title: Mounting base
Inventor: GRUNT STANISLAV
IPC: E03D11/13
Filed: 2001-03-08
Abstract: The present invention relates to a mounting base (2) intended for sanitary installation having two vertical load-bearing bars (9) arranged at a certain distance from each another and being coupled at their upper ends by an upper cross beam (7) and being coupled at their bottom ends by other beams (12) for attaching a water closet bowel, and between which there can be attached a water tank (10) disposed underneath the plaster. The proposed mounting base (2) is provided at its one end with foot supports (4) arranged on the floor (15), and at its upper end it has at least two supports disposed at a certain distance from each another and attachable to building walls (16). Both these supports are performed as side supports (3) projecting laterally substantially parallel to the mounting base (2) plane and serving for attaching the mounting base (2) to opposite sidewalls (16). The side supports (3) do not project in front of the mounting base (2) front side, and are seated on the upper crossbeam (7) thereof.
Patent CZ-303627-B6 (CZ)
Title: Process for preparing cinacalcet
Inventor: VLASAKOVA RUZENA
IPC: C07C209/68
Filed: 2011-11-25
Abstract: In the present invention, there is disclosed a process for preparing cinacalcet of the general formula I and pharmaceutically acceptable salts thereof, which preparation process is characterized by direct alkylation of (R)-(1-naphthyl)ethylamine of the general formula III with 3-[3-(trifluoromethyl)phenyl]propanol of the general formula II, in the presence of a catalyst in an inert organic solvent.
Patent SK-287752-B6 (SK)
Title: Triphenylalkene derivatives, pharmaceutical composition containing them and their use as selective estrogen receptor modulators
Inventor: SODERVALL MARJA-LIISA
IPC: C07D521/00
Filed: 2000-11-01
Abstract: Described are selective estrogen receptor modulator compounds of the general formula (I), wherein R1 is H, halogen, OCH3, OH; and R2 is a) -X-(CH2)n-CH2-N(R4)R5 where i) X is NH or S; and n is an integer from 1 to 4; and R4 and R5, which are the same or different, are a 1 to 4 carbon alkyl, H, -CH2CCH or -CH2CH2OH; or R4 and R5 form an N-containing five- or six-membered ring or heteroaromatic ring; or where ii) X is O and n is an integer from 1 to 4; and one of R4 and R5 is -CH2CCH or -CH2CH2OH and the other is H or C1-C4-alkyl; or R4 and R5 form an imidazole ring, an N-containing six-membered ring or heteroaromatic ring; or R2 is b) -Y-(CH2)nCH2-O-R6, where i) Y is O and n is an integer from 1 to 4; and R6 is -CH2CH2OH or -CH2CH2Cl; or where ii) Y is NH or S and n is an integer from 1 to 4 and R6 is H, -CH2CH2OH or -CH2CH2Cl; or R2 is c) 2,3-dihydroxypropoxy, 2-methylthioethoxy, 2-chloroethoxy, 1-ethyl-2-hydroxyethoxy or 2,2-diethyl-2-hydroxyethoxy; and R3 is H, halogen, OH or -OCH3; or their non-toxic pharmaceutically acceptable salts and esters and mixtures thereof.
Patent CZ-299695-B6 (CZ)
Title: 1,3-Disubstituted ureas functioning as ACAT inhibitors and process of their preparation
Inventor: OREMUS VLADIMIR
IPC: A61K31/4402
Filed: 1998-12-16
Abstract: The present invention relates to 1,3-disubstituted ureas of the general formula I where the symbol Re1 is as specified in the Claim, Re2 represents a nitro and/or amino group, and X denotes oxygen and/or sulfur, and the method of preparing thereof which method consists in treating aromatic amine of the general formula II with an isocyanate of the general formula III. The isocyanate of the general formula may be formed in situ and the reaction is carried out in toluene, at a temperature of 80 degC. If the nitro group is formed, it is reduced with hydrogen in the presence of palladium catalyst to yield the amino group. The obtained 1,3-disubstituted ureas are inhibitors of the activity of the acyl co-enzyme A: cholesterol acyltransferase (ACAT) enzyme, and may be used to inhibit cholesterol esterification and absorption in hypercholesterolemia.
Patent CZ-302354-B6 (CZ)
Title: Method for cleaning coke oven gas
Inventor: THIELERT HOLGER
IPC: B01D61/02
Filed: 2002-05-07
Abstract: The present invention relates to a method for cleaning coke oven gas by washing the gas, whereby sodium hydroxide as the washing liquid is guided into a washing liquid circuit and impurities in said washing liquid are expelled in a desorber, for regeneration of the sodium hydroxide, and whereby the coke oven gas is washed with the washing liquid in a counter-flow, characterized in that washing of the gas is operated in two stages, and comprises a first alkaline washing stage for the acidic gas components, as well as a second washing stage that works in the neutral to acidic pH range, for the absorption of ammonia, whereby the coke oven gas to be cleaned is passed in at the foot of the second washing stage, flows through the two washing stages, one after the other, and is drawn off at the head of the first washing stage, whereby the sodium hydroxide is added in at the head of the first washing stage, whereby the washing liquid that flows out of the first washing stage is passed to a top segment of the second washing stage, and whereby the pH of the washing liquid is lowered, by the absorption of the acidic gas components, to such an extent that the washing liquid can be used for the absorption of ammonia in the second washing stage.
Patent SK-286513-B6 (SK)
Title: Use of 4-fluoro-N-indan-2-yl benzamide for the manufacture of a medicament
Inventor: WOHLFART PAULUS
IPC: A61K31/00
Filed: 2002-02-12
Abstract: Described is use of 4-fluoro-N-indan-2-yl benzamide for the manufacture of a medicament for the treatment of stable or unstable angina pectoris, coronary heart disease, Prinzmetal angina, acute coronary syndrome, heart failure, myocardial infarction, stroke, thrombosis, peripheral artery occlusive disease, atherosclerosis, restenosis, endothel damage after PTCA, hypertension, essential hypertension, pulmonary hypertension, secondary hypertension, renovacsular hypertension, chronic glomerulonephritis, erectile dysfunction, ventricular arrhythmia, diabetes, nephropathy, retinopathy, angiogemesis, asthma bronchiale, chronic renal failure, cirrhosis of the liver or osteoporosis, or for the lowering of cardiovascular risk of postmenopausal women or after intake of contraceptive.
Patent SK-287714-B6 (SK)
Title: Use of amino acid derivative for the preparation of pharmaceutical compositions for treating phantom pain or diabetic neuropathic pain
Inventor: SELVE NORMA
IPC: A61P23/00
Filed: 2002-03-19
Abstract: The present invention concerns the use amino acid derivative of formula (I), where Ar is phenyl which is unsubstituted or substituted with at least one halogen substituents, Q is lower alkoxy containing 1 to 3 carbon atoms and Q1 is methyl, or a pharmaceutically acceptable salt thereof for preparing a pharmaceutical composition for the treatment of phantom pain or diabetic neuropathic pain.
Patent BR-PI0307620-B8 (BR)
Title: moléculas de polinucleotídeo codificando variantes de avec, métodos para produzir uma cepa recombinante de streptomyces avermitilis, bem como as referidas células recombinantes e composição de avermectinas
Inventor: KREBBER ANKE
IPC: C12N1/21
Filed: 2003-01-31
Abstract: "gene streptomyces avermitilis que dirige a razão de avermectinas b2:b1". a presente invenção refere-se a moléculas de polinucleotídeo compreendendo seqüências de nucleotídeos codificando um produto gene avec, cujas moléculas de polinucleotídeo podem ser usadas para alterar a razão ou quantidade da classe 2:1 de avermectinas produzida em culturas de fermentação de s. avermitilis. a presente invenção refere-se ainda a vetores, células hospedeiras, e cepas mutantes de s. avermitilis em que o gene avec tenha sido inativado ou submetido à mutação de modo a modificar a razão ou quantidade de avermectina da classe 2:1 produzida.
Patent RO-117107-B8 (RO)
Title: Adhesive composition for gluing massive wood and process for applying the same
Inventor: NEGREANU-PIRJOL TICUŢA
IPC: C09J189/04
Filed: 1996-08-28
Abstract: The invention relates to an adhesive composition for gluing wood and to a process for applying the same. According to the invention, the composition comprises 48 parts of dry bone glue, 40.5 parts of water, 1.35 parts of sodium tetraborate, 5.5 parts of granulated urea and 4.5 parts of potassium bichromate, the parts being expressed by weight. According to the invention, the process consists in heating the adhesive composition at a temperature of 50 ...60° C and applying said composition after homogenization onto the surface on the massive wood to be glued, which is brought to a temperature of 50 ...65° C, the working environment temperature being of 28 ...32° C.
Patent BR-PI0415288-B8 (BR)
Inventor: CHRISTINE FRAUENFELDER
IPC: A61K9/22
Filed: 2004-10-14
Abstract: A crystalline form of a γ-aminobutyric acid analog, and methods of preparing same, are provided.