baber/WOPTO huggingface dataset:
Patent MX-2012013437-A (MX)
Title: Single b-cell cultivation method.
Inventor: ENDL JOSEF
IPC: G01N33/50
Filed: 2011-05-26
Abstract: Herein is reported a method for obtaining a B-cell comprising the following steps a) labeling B-cells, b) depositing the labeled B-cells as single cells, c) co- cultivating the single cell deposited B-cells with feeder cells, d) selecting a B-cell proliferating and secreting IgG in step c) and thereby obtaining a B-cell. The labeling can be of IgG+CD19+-B-cells, IgG+CD38+-B-cells, IgG+CD268+-B-cells, IgG-CD138+-B-cells, CD27+CD138+-B-cells or CD3-CD27+-B-cells. The method can comprise the step of incubating said B-cells at 37 Â°C for one hour in EL-4 B5 medium prior to the depositing step. The method can also comprise the step of centrifuging said single cell deposited B-cells prior to the co-cultivation. In the co- cultivation a feeder mix comprising interleukin-lbeta, and tumor necrosis factor alpha and Staphylococcus aureus strain Cowans cells or BAFF or interleukin-2 and/or interleukin-10 and/or interleukin-6 and/or interleukin-4 can be used.
Patent MX-2013000908-A (MX)
Title: Manufacture of active highly phosphorylated human n-acetylgalactosamine-6-sulfatase and uses thereof.
Inventor: ARAYA KIDISTI
IPC: C12N9/16
Filed: 2011-07-22
Abstract: This invention provides compositions of active highly phosphorylated human N- acetylgalactosamine-6-sulfatase (GALNS), and pharmaceutical compositions and formulations thereof, methods of producing and purifying GALNS, and its use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the GALNS enzyme, e.g., Mucopolysaccharidosis IVa (MPS IVa or Morquio A syndrome).
Patent MX-2013001372-A (MX)
Title: Melt-fabricable tetrafluoroethylene/perfluoro (alky vinyl ether) copolymer composition having improved heat aging property.
Inventor: LAHIJANI JACOB
IPC: B29C71/00
Filed: 2011-08-05
Abstract: Heat aging of the composition comprising melt-fabricable tetrafluoroethylene/perfluoro(alkyl vinyl ether) copolymer, the alkyl containing 1 to 5 carbon atoms and melt flowable polytetrafluoroethylene is effective to cause thermal transformation of the composition in the solid state, characterized by epitaxial co-crystallization of the polymer components of the composition, and other valuable changes, such as increased continuous use temperature.
Patent MX-2013001831-A (MX)
Title: Anti-theft safety valve for fuel injection and electric pump motor vehicles.
Inventor: UREÑA JESUS AGUILAR
IPC: B60R25/042
Filed: 2013-02-14
Abstract: The present invention has an electric valve for the fuel pump in vehicles, which prevents vehicles from being stolen when these are parked; although the invention does not avoid the armed robbery, it helps the vehicle to be recovered some minutes later. The valve is made of aluminum or antimony preferably, it has an upper body, where the lock is mounted, also including a lower body where the supply is ungrounded. The upper body is mounted on the floor of the vehicle through an orifice performed at the front portion of the driver. This is mounted by means of a fixing nut. The valve is hidden by the carpet of the vehicle. The grounding switch is located at the lower portion thereof.
Patent MX-2013002007-A (MX)
Title: Devices and methods for intravaginal delivery of drugs and other substances.
Inventor: KISER PATRICK F
IPC: A61K9/14
Filed: 2011-08-19
Abstract: The present technology provides intravaginal devices designed to intravaginally deliver difficult to formulate water-soluble molecules and macromolecules for a sustained period of time. The devices include a chamber having at least one orifice and containing a sustained-release formulation. Such formulations include a water-swellable polymer and an intravaginally administrable substance. Methods of making and using the devices are also provided.
Patent MX-2013002266-A (MX)
Title: Seat belt adjustment apparatus.
Inventor: SUN YINGUI
IPC: B60R22/34
Filed: 2011-08-26
Abstract: An adjustment apparatus for a seat belt on a vehicle. The apparatus comprises: a pair of levers (2) constituted by a first lever and a second lever; the first lever and the second lever are hinged together at their adjacent ends forming a lever angle (Î±); and actuators (3, and 6). The actuators apply force on the first lever and/or the second lever and/or the lever hinge point (a1) to change the angle between the levers, thereby directly exerting a force of changing magnitudes on the seat belt via the non-adjacent ends.
Patent MX-2013007903-A (MX)
Title: Anti-scratch formula based on natural materials.
Inventor: MONTEROS CARLOS CANALES ESPINOSA DE LOS
IPC: A61K36/00
Filed: 2013-07-05
Abstract: The present invention protects a disposable hygiene item, which is characterized in that it has a formula for promoting the care of the skin by means of the use of natural compounds such as cane wax, which has healing and anti-inflammatory pharmacological properties; the formulation may also contain an agent for neutralizing malodors, such as chlorophyll, an antimicrobial agent such as the grapefruit seed extract and a fragrance.
Patent MX-2013008996-A (MX)
Title: Novel pharmaceutical system of biphasic delivery for treating pain and inflammation.
Inventor: AMEZCUA FEDERICO AMEZCUA
IPC: A61K31/137
Filed: 2013-08-02
Abstract: The present invention refers to stable pharmaceutical compositions comprising a tablet-tablet system that consists in the compression of a tablet within another tablet with a biphasic delivery system of at least an analogue of (1R, 2R)-rel-2-[(dimethylamine) methyl]-1-(3 metoxifenil) cyclohexanol (Tramadol) and/or the pharmaceutically acceptable salts thereof and/or an analogue of 2-[2,6-dichlorophenyl)amine] benzeneacetic acid carboxymethyl ester (aceclofenac) and/or the stable pharmaceutical salts thereof contained in the tablet. Said compositions are useful for the control and/or prevention and/or treatment of acute and/or chronic pain as well as the acute and/or chronic inflammation.
Patent MX-2013010049-A (MX)
Title: Method for manufacturing continuous composite tube, apparatus for manufacturing continuous composite tube.
Inventor: KREMERS MARCUS ANTONIUS IVONNE
IPC: F16L9/16
Filed: 2012-03-05
Abstract: Method for manufacturing a continuous composite tube comprising translating a tube liner through a manufacturing station wherein the manufacturing station comprises a winding station and a consolidation station located at a distance downstream of the winding station; winding a composite tape on the tube liner at the winding station for forming a tape layer; consolidating the composite tape on the tube liner at a consolidation zone of the consolidation station by pressing and heating to the tape.
Patent MX-2014000774-A (MX)
Title: Collector for bipolar lithium ion secondary batteries.
Inventor: TANAKA YASUYUKI
IPC: H01M10/0585
Filed: 2012-07-18
Abstract: A collector (3) for bipolar lithium ion secondary batteries of the present invention comprises: a first conductive layer (3A) that is obtained by adding a conductive filler to a base that contains an imide group-containing resin; and a second conductive layer (3B) that has a function of blocking lithium ions. The second conductive layer (3B) comprises: a blocking resin layer (3a) that is obtained by adding a conductive filler to a base that contains a resin which contains no imide group; and a metal layer (3b). This collector (3) for bipolar lithium ion secondary batteries is used in such a manner that the first conductive layer (3A) is on the positive electrode active material layer side with respect to the second conductive layer (3B).
Patent MX-2014003312-A (MX)
Title: Novel glucagon analogues.
Inventor: LAU JESPER F
IPC: A61K38/00
Filed: 2012-09-21
Abstract: The present invention relates to novel glucagon peptides, to the use of said glucagon peptides in therapy, to methods of treatment comprising administration of said glucagon peptides to patients in need thereof, and to the use of said glucagon peptides in the manufacture of medicaments. The glucagon peptides of the present invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
Patent MX-2014003784-A (MX)
Title: Tire with tread having improved snow and dry traction.
Inventor: GUICHON CYRIL
IPC: B60C11/12
Filed: 2012-09-05
Abstract: This invention relates generally to tires having treads that have a configuration and/or properties for providing suitable snow and dry traction, and, more specifically, to a tire that has a tread that has a maximum value for sipe density in the contact patch, a minimum value for lateral groove density in the contact patch, and a minimum value for the longitudinal contact surface ratio. In certain embodiments, the pitch length of pitches or repeating units of tread geometry along the circumferential direction of the tire is within a certain range and the tread depth is below a specified value. Tires with treads having a configuration that falls within these design parameters exhibit a desirably good level of snow and dry traction.
Patent MX-2014005996-A (MX)
Title: Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or an anti-adm non-ig scaffold for use in therapy.
Inventor: BERGMANN ANDREAS
IPC: A61P13/12
Filed: 2012-11-16
Abstract: Subject matter of the present disclosure is an anti-adrenomedullin antibody or an anti-adrenomedullin antibody fragment or anti-ADM non- lg scaffold wherein said antibody or said fragment or scaffold is a non- neutralizing antibody, antibody fragment or non-lg scaffold, respectively. Subject matter of the present disclosure is also an anti-adrenomedullin antibody or an anti-adrenomedullin antibody fragment or anti-ADM non-lg scaffold for use in a treatment of a chronic or acute disease wherein said antibody or fragment or scaffold is: an ADM stabilizing antibody or an adrenomedullin stabilizing antibody fragment or an ADM stabilizing non-lg scaffold that enhances the t1/2 half retention time of adrenomedullin in serum, blood, plasma at least 10 %, preferably at least, 50 %, more preferably > 50 %, most preferably 100 % and/or wherein said anti-ADM antibody or an anti-adrenomedullin antibody fragment or anti-ADM non-lg scaffold blocks the bioactivity of ADM to not more than 80 %, or not more than 50 %.
Patent MX-2014010210-A (MX)
Title: Preparing a precured tread for application to a tire carcass.
Inventor: IKONOMOV METODI L
IPC: B29D30/58
Filed: 2012-02-29
Abstract: The present invention comprises methods and apparatus for preparing a tread for application to a tire carcass by abrading a bottom side of the tread. In particular, the tread has a thickness extending depthwise between a top side and a bottom side of the tread. The tread thickness extends in a longitudinal direction and in a lateral direction between opposing sides of the tread. The tread further includes a void extending within the tread thickness and an extension of the tread extending across a width of the void and as a portion protruding outwardly from the tread bottom side by a distance. Such methods include stretching the tread such that the width of the tread void increases and the distance by which the extension protrudes from the bottom side decreases. Such methods further include abrading the bottom side of the tread.
Patent MX-2014011749-A (MX)
Title: Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection.
Inventor: GUO LEI
IPC: C07D409/14
Filed: 2013-03-26
Abstract: The invention provides novel compounds having the general formula (I): wherein R1, R2, R3, R4, R5, M and X are as described herein, compositions including the compounds and methods of using the compounds.
Patent MX-2014013771-A (MX)
Title: Liquid dispensing device for delivering accurate dose.
Inventor: JATHAR SHRIPAD
IPC: B65D47/24
Filed: 2013-05-16
Abstract: The present invention provides an integrated liquid dispensing device for delivering accurate and/or measured and/or metered and/or pre-determined dose of oral liquids comprising a container for holding liquid medicine and a dispensing device fitted on the opening of the container. The dispensing device is characterized by use of a shut off valve mechanism or a twist lock mechanism or a spring valve mechanism for dispensing the liquid.
Patent MX-2015001226-A (MX)
Title: Three-dimensional object detection device and three-dimensional object detection method.
Inventor: HAYAKAWA YASUHISA
IPC: G01N21/61
Filed: 2013-07-25
Abstract: This three-dimensional object detection device is characterized by being provided with: a first three-dimensional object detection means (33) that detects three-dimensional objects on the basis of a captured image; a light source detection means (34) that detects light sources present rearwards from the vehicle of the device; a second three-dimensional object detection means (35) that detects three-dimensional objects on the basis of the light sources; a three-dimensional object determination means (37) that determines whether or not a three-dimensional object is an neighboring vehicle; a cloudiness calculation means (38) that calculates a lens cloudiness on the basis of a captured image; and a control means (37) that determines whether or not a three-dimensional object is a neighboring vehicle on the basis of the detection results by at least the second three-dimensional object detection means when the lens cloudiness is at least a predetermined determination value, and determines whether or not a three-dimensional object is a neighboring vehicle on the basis of the detection results of at least the first three-dimensional object detection means when the lens cloudiness is less than the determination value.
Patent MX-2015001905-A (MX)
Title: Azaheterocycles as bir2 and/or bir3 inhibitors.
Inventor: LOU YAN
IPC: A61K31/47
Filed: 2013-08-06
Abstract: Disclosed are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, m, n and q are described in this application, and methods of using said compounds in the treatment of cancer.
Patent MX-2015004896-A (MX)
Title: Compositions comprising peroxy acid.
Inventor: NEAS EDWIN D
IPC: A01N37/16
Filed: 2013-10-18
Abstract: The present invention provides methods for producing a non Î±-keto peracid that has lower toxicity and lower corrosivity. The present embodiments also provide methods and compositions for reducing microbes on a surface, methods and compositions for preventing and reducing infectious vegetative bacteria on a substrate, and methods and compositions for treating a wound. In particular, compositions of the invention provide for a mixture of an Î±-keto peracid and a non Î±-keto peracid that works synergistically to reduce microbes on a surface, to prevent vegetative bacteria on a surface and to heal a wound in animals or humans.
Patent MX-2015005739-A (MX)
Title: Novel benzyl sulfonamide compounds useful as mogat-2 inhibitors.
Inventor: STACK DOUGLAS RICHARD
IPC: C07D217/00
Filed: 2013-10-30
Abstract: The present invention provides compounds of Formula I. Wherein Rl, L, and A are as described herein, or a pharmaceutical salt thereof, processes for preparing the compounds, and methods of treating a condition, such as hypertriglyceridemia, using the compounds.
Patent MX-2015005855-A (MX)
Title: Hydraulic shock absorber for suspension system and corresponding improved hydraulic stop.
Inventor: SOROMENHO GERALDO BONTEMPI
IPC: F16F7/08
Filed: 2013-04-10
Abstract: The invention relates to a hydraulic shock absorber for a suspension system and to the corresponding improved hydraulic stop, the hydraulic shock absorber comprising a tubular shell, a tubular body (20) and an axially movable, reciprocating rod provided with an elastomeric, stroke-limiting annular element. The stroke-limiting element (6) comprises a retention ring (7), a locking ring (8) and a sealing ring (9), the retention ring (7) partially enclosing the locking ring (8) and defining, together with the locking ring (8), a groove (91) for accommodating the sealing ring (9).
Patent MX-2015007112-A (MX)
Title: Composite panel edge treatments and joints and cargo body having same.
Inventor: FENTON GARY L
IPC: B62D63/06
Filed: 2015-06-04
Abstract: A cargo body includes sidewalls constructed of pairs of panels secured together at respective joints. Each panel is an assembled panel having a core, an interior skin, and an exterior skin. In some cases, each joint is formed to include overlapping edge portions of first and second ones of the adjacent pair of panels. Each of the overlapping edge portions has a thickness less than 20 percent of a total panel thickness of the corresponding one of the adjacent pair of panels such that the joint formed thereby defines a recess between co-facing edge portions of the first and second ones of the adjacent pair of panels. A profile insert defining a longitudinal channel is positioned in the recess defined by the overlapping edge portions at each joint. Each joint is secured by fixedly attaching the profile insert to the overlapping edge portions.
Patent MX-2015007989-A (MX)
Title: Oral care implement having pressure sensor and method of forming the same.
Inventor: BLOCH BRIAN
IPC: A46B15/00
Filed: 2013-03-18
Abstract: A toothbrush having a pressure sensor. In one embodiment, the invention can be a toothbrush comprising: a handle; a head; a plurality of tooth cleaning elements mounted to and extending from a front surface of the head; a printed circuit board located within the head, the printed circuit board having a front surface and a rear surface; a pressure sensor operably coupled to a front surface of the printed circuit board, wherein pressure applied to the plurality of tooth cleaning elements is transmitted to the pressure sensor; and a light source attached to a rear surface of the printed circuit board, wherein the light source is illuminated upon the pressure sensor being subjected to a pressure that exceeds a predetermined threshold.
Patent MX-2015008447-A (MX)
Title: Re-ranking story content.
Inventor: CLAIR LUKE ST
IPC: G06Q50/10
Filed: 2013-12-30
Abstract: In one embodiment, a method includes receiving a cover feed interaction history from a device associated with a user of a social-networking system. An order for a plurality of content boards may be determined based on the cover feed interaction history (e.g., viewing history, download status, the current order of content boards in the cover feed, user interaction history, whether the user bookmarked or pinned a particular content board), user information related to the user, and device information about device-based events and device status. Finally, the order for the content boards may be sent to the device. The determination of the order for the content boards may be based on the cover feed interaction history, recency of content included in the content boards, popularity of the content, relevance of content to the user, or device-based events.
Patent MX-2015010665-A (MX)
Title: Absorbing, reflecting and collimating polarizer stack and backlights incorporating same.
Inventor: HAAG ADAM D
IPC: G02B5/30
Filed: 2014-02-10
Abstract: Polarizer stacks are described. More particularly, polarizer stacks that include an absorbing polarizer and multiple reflective polarizers, including at least one collimating reflective polarizer are described. Such polarizer stacks are capable of emitted light that is both collimated and color neutral. Backlights incorporating such polarizer stacks are also described.
Patent MX-2015011566-A (MX)
Title: Novel abexinostate salt, associated crystalline form, preparation method thereof and the pharmaceutical compositions containing same.
Inventor: LETELLIER PHILIPPE
IPC: A61P29/00
Filed: 2014-03-03
Abstract: The invention relates to abexinostate tosylate of formula (II): and the crystalline form I thereof, characterized by the powder diffraction pattern X thereof, the Raman spectrum thereof, and the solid state 13C CP/MAS NMR spectrum thereof. The invention is useful in the field of drugs.
Patent MX-2015012136-A (MX)
Title: Rapidly dispersible dosage form of oxcarbazepine.
Inventor: WEST THOMAS G
IPC: A61K31/55
Filed: 2014-03-14
Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof. A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof. The present invention relates to the preparation of substantially purified anti- EDA1 monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof as well as pharmaceutical compositions containing such antibodies. The antibodies may be used in the treatment of disorders relating to excessive action of EDA1 such as hirsutism, ectopic teeth, hyperhidrosis, breast cancer, dermal eccrine cylindroma or skin disorders such as sebaceous gland hyperplasia, comedones, milia, acne, seborrhea, rosacea, steatoma, and furuncles. The anti-EDA1 antibodies are also useful in immunoassays such as sandwich ELISA.
Patent MX-2015012597-A (MX)
Title: An apparatus for producing a nonwoven product in a non-industrial environment.
Inventor: GILOH EHUD
IPC: D04H1/58
Filed: 2014-03-14
Abstract: An apparatus for producing a non-woven product is disclosed. The apparatus is located substantially within an enclosure and includes a mold or former and at least two moveable material application heads. A controller controls various elements located within or connected to the enclosure. The footprint of the enclosure is smaller than 2m x 2m.
Patent MX-2015014017-A (MX)
Title: Fc region variant.
Inventor: IGAWA TOMOYUKI
IPC: C12N15/00
Filed: 2014-04-02
Abstract: It is found that a polypeptide, which contains an antibody Fc region variant that comprises an amino acid sequence composed of a combination of an alteration of an amino acid residue located at position-238 as numbered in accordance with the EU index and an alteration of another specific amino acid residue, has a reduced binding activity to all of active FcÎ³R's, especially to FcÎ³RIIa (type R), compared with polypeptides each containing a naturally occurring IgG Fc region, while maintaining the binding activity thereof to FcÎ³RIIb.
Patent MX-2016002978-A (MX)
Title: Downhole wireline cleaning tool.
Inventor: JENSEN SVEN KARSTEN
IPC: E21B4/04
Filed: 2014-09-16
Abstract: Downhole wireline cleaning tool (1) adapted to scrape and remove objects, such as scale decreasing an inner diameter of a casing in a wellbore, comprising a tool housing (4) having a first housing part (5) and a second housing part (6), a projectable arm (7) which is pivotably connected with the first housing part at a first end of the projectable arm, the projectable arm having a plurality of bits (9) in a second end, said projectable arm (7) being movable between a retracted position and a projected position in relation to the tool housing (4), an arm activation assembly (11) for moving the projectable arm between the retracted position and the projected position, and a rotatable shaft (12) for rotating the projectable arm (7), wherein the bits are arranged along an extension of the projectable arm, wherein the extension of the arm extends across the centre tool axis in at least the retracted position, so that the bits of the arm are arranged to scrape the entire internal cross-sectional area of the casing..