baber/WOPTO huggingface dataset:
Patent AT-E175215-T1 (AT)
Inventor: THIERFELDER STEFAN
IPC: A61K39/395
Filed: 1995-05-19
Granted: 1999-01-15
Abstract: The invention relates to antibodies to T cells as therapeutics. The object underlying the invention is to provide antibodies for a clinical therapy for prolonging the immunosuppressive antibody effect while avoiding the formation of antiantibodies. This object is achieved by providing antibodies consisting of at least two different groups which are applied at different times and in which at least one antibody of group B differs from one antibody of group A in the constant regions of its heavy chains and wherein group A, which is first applied once or several times, has a T-cell eliminating effect, while the other group B (which is applied at a different time) has a T-cell eliminating and/or T-cell antigen modulating effect.
Patent AT-E196765-T1 (AT)
Inventor: AMSCHLER HERMANN
IPC: A61K31/34
Filed: 1995-07-19
Granted: 2000-10-15
Abstract: PCT No. PCT/EP95/02841 Sec. 371 Date Apr. 15, 1997 Sec. 102(e) Date Apr. 15, 1997 PCT Filed Jul. 19, 1995 PCT Pub. No. WO96/03399 PCT Pub. Date Feb. 8, 1996The invention concerns componuds of formula (I), in which R1, R2, R3 and R4 have the meanings given in the description. The compounds are novel, effective PDE-inhibitors.
Patent AT-E226695-T1 (AT)
Inventor: SMITH STEWART GREGORY
IPC: B60G17/005
Filed: 1995-07-28
Granted: 2002-11-15
Abstract: In a vehicle having a transverse axle and a body, and a shock absorber mounted between the axle and the body to absorb shock from vertical movement of the axle and prevent shock from being transmitted completely to the body, the improvement disclosed involves apparatus for sensing tilt of the axle in combination with separate hydraulic system to prevent further tilt of the axle beyond a predetermined point sensed by the sensing unit.
Patent AT-E165926-T1 (AT)
Inventor: BJORNER JOHANNES ARNE SCHIONNI
IPC: G06K7/015
Filed: 1995-08-14
Granted: 1998-05-15
Abstract: An optical system for adjusting the optical path between a detector and an object, such as an information-encoded label affixed to a package. The optical system comprises a pair of movable mirrors and an array of fixed mirrors. One of the movable mirrors is positionable to direct an image reflected from the object to any one of the array of fixed mirrors. The other of the movable mirrors is positionable to direct the image reflected by the fixed mirror to the detector. The positions of the movable mirrors are adjusted responsive to variations in the measured height of different objects.
Patent AT-E242349-T1 (AT)
Inventor: QUANTRILLE THOMAS E
IPC: A61F13/511
Filed: 1995-11-22
Granted: 2003-06-15
Abstract: The present invention provides a composite nonwoven fabric with a superior combination of extensibility, tensile properties and abrasion resistance. The composite nonwoven fabric (10) comprises at least one layer containing multipolymer fibers, with a plurality of bonds (B) bonding the fibers together to form a coherent extensible nonwoven web (11). This coherent extensible nonwoven web (11) has a Taber surface abrasion value (rubber wheel) of greater than 10 cycles and an elongation at peak load in at least one of the machine direction or the cross-machine direction of at least 70 percent. A second extensible layer (12) is laminated to this coherent extensible nonwoven web (11) by an adhesive layer (13).
Patent AT-E179061-T1 (AT)
Inventor: CONNERS JOHN A
IPC: A61B17/12
Filed: 1993-05-27
Granted: 1999-05-15
Abstract: A two-part surgical ligation clip includes a track having two substantially symmetrical arms and a clip for slidably receiving the track. The symmetrical arms are connected together at a proximal end to form an apex and have spaced-apart tips at a distal end with first complementary surface. The track also includes a connector connected to the apex and having a second complementary surface. The clip has an extended slot for slidably engaging the track and distal end tips for receiving the connector. A distal end of the clip has a first contour surface for engaging the first complementary surface on the track and locking it in a closed position and a second contour surface for engaging the second complementary surface on the track and locking it in an open position. A two-part ligation clip applicator, which is also disclosed, comprises a handle assembly having a squeezable trigger and an elongated shaft connected at its proximal end to the handle assembly. The elongated shaft houses a sliding advancer which is actuated by squeezing the trigger to move axially in a forward direction in the shaft. In addition, a module is mountable at a distal end of the elongated shaft and supports a ligation clip. The module has a cartridge housing, latches pivotably mounted within the housing for gripping first part of the ligation clip, and a sliding pusher slidable within the housing by actuation of the advancer to engage the second part of the ligation clip and advance it relative to the first part to close the first part.
Patent AT-E236286-T1 (AT)
Inventor: HUBER BERND
IPC: A61L15/28
Filed: 1996-01-29
Granted: 2003-04-15
Abstract: A method of treating a surface of a fibre, e.g. cellulosic fibre, with a finish in which the surface finish is applied as an aqueous emulsion stabilised at a first pH value and at the latest when applied to the fibre the emulsion is caused to destabilise by a change in the first pH value. The invention also relates to cellulosic fibre and threads thereof and to tampons made from cellulosic fibre.
Patent AT-E230759-T1 (AT)
Inventor: TAVTIGIAN SEAN V
IPC: A61K48/00
Filed: 1996-12-17
Granted: 2003-01-15
Abstract: The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human breast cancer predisposing gene (BRCA2), some mutant alleles of which cause susceptibility to cancer, in particular breast cancer. More specifically, the invention relates to germline mutations in the BRCA2 gene and their use in the diagnosis of predisposition to breast cancer. The present invention further relates to somatic mutations in the BRCA2 gene in human breast cancer and their use in the diagnosis and prognosis of human breast cancer. Additionally, the invention relates to somatic mutations in the BRCA2 gene in other human cancers and their use in the diagnosis and prognosis of human cancers. The invention also relates to the therapy of human cancers which have a mutation in the BRCA2 gene, including gene therapy, protein replacement therapy and protein mimetics. The invention further relates to the screening of drugs for cancer therapy. Finally, the invention relates to the screening of the BRCA2 gene for mutations, which are useful for diagnosing the predisposition to breast cancer.
Patent AT-E189274-T1 (AT)
Inventor: MIDDEKE HERMANN
IPC: C25D5/54
Filed: 1996-03-15
Granted: 2000-02-15
Abstract: The invention concerns a process for the selective or partial electrolytic metallization of surfaces of substrates made from electrically non-conducting materials which for the purpose of the coating process are secured to plastic-coated holding elements. The proposed process involves the following steps: a) preliminary treatment of the surfaces with an etching solution containing chromium (VI) oxide; followed immediately by b) treatment of the surfaces with a colloidal acidic solution of palladium-/zinc compounds, care being taken to prevent prior contact with adsorption-promoting solutions; c) treatment of the surfaces with a solution containing a soluble metal compound capable of being reduced by zinc (II) compounds, an alkali or alkaline earth metal hydroxide, and a complex forming agent for the metal in a quantity sufficient at least to prevent precipitation of metal hydroxides; d) treatment of the surfaces with an electrolytic metallization solution. By applying this process, it is possible to ensure that only the surfaces of the work piece are coated with metal, not the holding elements or, where applicable, non-conductive plastic layers applied to parts of the work pieces. In addition, the process facilitates direct electrolytic metallization even of large plastic surfaces without prior currentless metallization.
Patent AT-E266731-T1 (AT)
Inventor: GIORDANO ANTONIO
IPC: C12N15/09
Filed: 1996-03-14
Granted: 2004-05-15
Abstract: Substantially pure human cyclin-dependent kinase-like proteins PITALRE and PISSLRE and isolated protein complexes that comprise PITALRE or PISSLRE are disclosed. Isolated nucleic acid molecule that encode PITALRE or PISSLRE, or a fragment thereof; recombinant expression vectors that comprise nucleic acid sequence that encode PITALRE or PISSLRE; and host cells that comprise such recombinant expression vectors are disclosed. Oligonucleotide molecules that consist of a nucleotide sequence complimentary to a portion of the nucleotide sequence that encodes PITALRE or PISSLRE are disclosed. Antibodies which bind to epitopes on PITALRE or PISSLRE are disclosed. Nucleic acid molecules that comprise a nucleotide sequence that encodes phosphorylation deficient PITALRE, or a phosphorylation deficient PI SSLRE; recombinant vectors and pharmaceutical compositions that comprise such nucleotide sequences are also disclosed. Methods of identifying compounds which inhibit PITALRE activity are disclosed.
Patent AT-E196832-T1 (AT)
Inventor: PAVELESCU LIVIU-MIHAI
IPC: A43B7/12
Filed: 1996-05-31
Granted: 2000-10-15
Abstract: PCT No. PCT/EP96/02362 Sec. 371 Date Nov. 21, 1997 Sec. 102(e) Date Nov. 21, 1997 PCT Filed May 31, 1996 PCT Pub. No. WO96/41549 PCT Pub. Date Dec. 27, 1996A shoe structure includes an upper, including at least an outer layer and a lining, an insole, and a sole. The lining lines the inside of the outer layer and includes a waterproof and water-vapor permeable functional layer. The insole is connected to a lower end area of the outer layer. The lower end area of the lining is turned back to the inside in the sole area at least approximately parallel to the direction in which the sole extends, whereby the turned back area of the lining is shortened to a width of between 0.5 and 3 cm. Cut-outs are made in the insole, at least in the area in which the turned back lower end area of the lining ends. The lower end area of the lining is embedded in a synthetic material which fills the cut-outs in the insole in such a manner that at least the surface of the end area of the lining facing the inner area of the shoe structure forms a continuous surface with the surface of the synthetic material facing the inner area of the shoe structure. The functional layer is bonded with the synthetic material in a waterproof manner in the lower end area of the lining and at the extreme edge area of the lining.
Patent AT-E210129-T1 (AT)
Inventor: YAZAKI AKIRA
IPC: C07D213/74
Filed: 1996-09-20
Granted: 2001-12-15
Abstract: Pyridine carboxylic acid derivs. of formula (I) and their salts are new: R1 = H or carboxy protecting gp; R2 = OH, lower alkoxy or opt. substd. amino; R3 = H or halo; R4 = H or halo; R5 = halo or opt. substd. cyclic amino; R6 = H, halo, NO2 or opt. protected amino; X, Y, Z = N, CH or CR7; R7 = lower alkyl, halo or CN; provided that \- 1 of X-Z = N; W = N or CR8; R8 = H, halo or lower alkyl.
Patent AT-E183551-T1 (AT)
Inventor: STANDAERT ROGER
IPC: B22F3/02
Filed: 1996-11-18
Granted: 1999-09-15
Abstract: A powder for sintering to manufacture a diamond tool has an average particle size of less than 8 mum and a loss of mass by reduction in hydrogen of less than 3% and contains 10-80% Fe, up to 40% Co, up to 60% Ni and up to 15% M. M is present, at least partially, in the oxidized state and representing one or more of the elements Mn, Cr, V., Al, Mo and Ti, the balance being unavoidable impurities. This powder may be sintered at 650-1000° C. to give a matrix having a high hardness.
Patent AT-E231726-T1 (AT)
Inventor: FITZGERALD JAMESINA ANNE
IPC: A61K31/415
Filed: 1996-11-22
Granted: 2003-02-15
Abstract: The subject invention encompasses methods for prevention and treatment of a human or lower animal subject having a gastrointestinal disorder caused or mediated by algae and/or cyanobacteria comprising administering to the subject bismuth and one or more antimicrobials. The subject invention also encompasses compositions comprising bismuth and one or more antimicrobials for the prevention and treatment of a human or lower animal subject having a gastrointestinal disorder caused or mediated by algae and/or cyanobacteria.
Patent AT-E181154-T1 (AT)
Inventor: HAUSER WOLFGANG
IPC: G01N29/00
Filed: 1996-12-06
Granted: 1999-06-15
Abstract: The invention relates to a pressure wave sensor consisting of a piezoelectric element (7) secured in a cylindrical housing (10), where the piezoelectric element (7) is pressed by a spring (4) against a front surface of the housing (10). The aim of the invention is to design a pressure wave sensor of the above kind in such a way that its sensitivity is increased. This is achieved in that the front of the housing consists of a metal foil (11) and there is a pressure pad (8) of soft metal between said metal foil (11) and the piezoelectric element (7).
Patent AT-E234636-T1 (AT)
Inventor: SINN HANNSJOERG
IPC: A61K31/00
Filed: 1996-12-20
Granted: 2003-04-15
Abstract: The present invention relates to conjugates, comprising an active substance, a polypeptide and a polyether, a process for the production of such conjugates as well as their use.
Patent AT-E233880-T1 (AT)
Inventor: GERSTBERGER CHRISTIAN
IPC: F21V19/00
Filed: 1997-01-17
Granted: 2003-03-15
Abstract: The lamp mounting (1), for small spaces and preassembly in wiring systems for automatic fitting, has a holder system (27,28) to hold the mounting (1) in the working position and also in a second setting for transport and fitting into place. The electrical contacts (7,8) are protected from contact with the mounting housing (2), and are accessed through at least one connection opening (4) in the housing (2) from one side. The cables, connected to the contacts (7,8), are accessible through openings at the other side of the housing (20 for connection to the wiring.
Patent AT-E221690-T1 (AT)
Inventor: JOHNSON KEITH O
IPC: G06F3/05
Filed: 1992-05-28
Granted: 2002-08-15
Abstract: A method for converting and encoding an analog signal to a digital format and subsequently decoding and converting said digital format to recover the analog signal, comprising the steps of monitoring the physical characteristics of an analog waveform to be converted to a digital format, converting said analog waveform to said digital format, encoding within said digital formal control information indicative of the physical characteristics of said analog waveform, whereby said analog waveform can subsequently be more accurately reconstructed from said digital format, decoding from said digital format said control information indicative of certain specified physical characteristics of said analog waveform, converting said digital format signal to said analog waveform, and peak limiting and restoring, and introducing compatible signal reconstruction compensation, in accordance with said control information during said converting process, said information facilitating subsequent more accurate reconstruction of said analog waveform from said digital format.
Patent AT-E239190-T1 (AT)
Inventor: HAHN THOMAS
IPC: A47F3/00
Filed: 1997-09-09
Granted: 2003-05-15
Abstract: The lighting arrangement is composed of several LEDs fastened on the surface area of a carrier disk, which are electrically connected with conductor paths on the carrier. The disk is formed as a crystal-clear glass plate (1) which is mounted in a display case for the display of objects, or forms a part of it. The conductor paths (2,3) are applied as an electrically conducting, thin and invisible or next to invisible layer on the glass disk.
Patent AT-E329234-T1 (AT)
Inventor: SPECKBACHER PETER DR
IPC: G01B11/00
Filed: 1997-12-11
Granted: 2006-06-15
Abstract: The position measuring unit has an illumination source (11) and a detector unit (20) for measuring the position of two objects moving relative to each other, with the help of light beam diffraction at one phase grating (2). This phase grating is a reflecting grating with webs (22) and gaps (23) arranged alternately in the measuring direction (X). The division cycle (TP) of the phase grating (2) is approximately the same or smaller than the wavelength ( lambda ) of the incident beam (13, 14). The webs (22) are designed at least approximately trapezium shaped, and the flanks (28) of the webs (22) are inclined against each other at equal angles ( ) smaller than 85 deg.
Patent AT-E300615-T1 (AT)
Inventor: LONBERG NILS
IPC: A61K39/395
Filed: 1991-08-28
Granted: 2005-08-15
Abstract: A transgenic mouse having a genome comprising a human immunoglobulin heavy chain minilocus transgene, the transgene being capable of rearrangement and switching in the mouse, whereby two or more rearranged human heavy chain isotypes are produced.
Patent AT-E251825-T1 (AT)
Inventor: FUKUDA KUNIO
IPC: H04L29/08
Filed: 1997-01-29
Granted: 2003-10-15
Abstract: In the data communication method in which the data frame transmitted from the transmission side to the reception side and the feedback frame transmitted from the reception side to the transmission side use a common format jointly, to propose a data communication method in which if there is no substantial data to be transported by the feedback frame on the reception side, the feedback frame is transmitted from the reception side to the transmission side without changing the format of the feedback frame and lowering the reception rate. In the data communication, the common format includes at least each data of the transmission data length, the transmission data, the data frame number and the repeat request frame number, and is added with the error detection code for the entirety of the data. If there is no substantial transmission data to be transported by the feedback frame on the reception side, then the feedback frame is arranged such that data unrelated to feedback information including at least the transmission data length, the transmission data and the data frame number within the feedback frame, are substituted with the predetermined fixed pattern, and thereafter an error detecting code for the entirety of the data is added thereto. Then, the feedback frame is transmitted from the reception side to the transmission side. <IMAGE>
Patent AT-E214553-T1 (AT)
Inventor: CORET MONROS SALVADOR
IPC: A23L1/09
Filed: 1997-08-18
Granted: 2002-04-15
Abstract: Process to obtain a food composition based on chufas and bananas. The chufas are crushed to obtain liquid chufa orgeat at a low temperature, from which the starch is separated and sodium caseinate, sugar and stabilizers added, as well as an emulsifier previously melted in hot water. On the other hand, peeled bananas are crushed with ascorbic and citric acids, filtering the resulting liquid. The chufa orgeat is mixed with the banana liquid with sugar and flavor for its packing under aseptic conditions.
Patent AT-E195582-T1 (AT)
Inventor: SPRINGMANN GEORG
IPC: B22D11/06
Filed: 1997-02-14
Granted: 2000-09-15
Abstract: The invention concerns a rotary transmission leadthrough for connecting a coolant feed to a roller, particularly for continuous casting plants, the roller being mounted in bearing brackets in roll bearings by means of journals and supplied with coolant via axial bores through the journals. The leadthrough has a housing (1); a rotor (2, 3, 4) rotatively mounted in the housing; a first sealing element (10) which turns with the rotor, is seated on the end of the rotor situated in the housing, and has a first sealing surface; a second sealing element (11) which has a second sealing surface facing the first sealing surface and which is supported by a cover (12) that fits into the housing at the end of the housing facing the interior of the roller, and an axial bore which passes through the rotor and the cover. The one-piece rotor comprises a rotor head (2) with end section which protrudes from the housing at the side of the housing facing away from the interior of the roller, to which rotor head a coolant feed or drain line can be attached, a rotor shaft (3) and a rotor foot (4), the rotor shaft taking the form of an elastic component.
Patent AT-E271839-T1 (AT)
Inventor: MILDER FREDRIC L
IPC: A61L2/16
Filed: 1997-04-16
Granted: 2004-08-15
Abstract: An iontophoretic material is provided that uses controlled electrical current derived from two dissimilar galvanic materials to drive oligodynamic metal ions into solution to kill microorganisms on and near the material. Iontophoretic structures or material associated with a medical device are partially or completely covered with one or more covering layers that alter physical, mechanical, chemical, or biological properties of the device and/or the iontophoretic material. In addition to being partially coated or completely enveloped by iontophoretic material or structures, all or a portion of a medical device can be integrated with, impregnated by, or fabricated from an iontophoretic material.
Patent AT-E219793-T1 (AT)
Inventor: JOOS STEFAN
IPC: C12N15/09
Filed: 1997-04-23
Granted: 2002-07-15
Abstract: The present invention relates to a process for identifying numerical changes in cell DNA, comprising the following steps: (a) isolating DNA from normal cells and amplifying the DNA by means of a PCR method using tag primers; (b) hybridizing cells under study in situ with the amplified DNA from (a); (c) amplifying DNA from the in situ hybridized cells from (b) by means of a PCR method using the tag primers from (a), and (d) identifying numerical changes in the amplified DNA from (c) in a normal way. In addition, the invention concerns a kit suitable for carrying out the process.
Patent AT-E321559-T1 (AT)
Inventor: THOMAS LAWRENCE J
IPC: C12N15/09
Filed: 1997-05-01
Granted: 2006-04-15
Abstract: A plasmid-based vaccine is provided herein based on the combination of DNA segments coding for one or more B cell epitopes of CETP and one or more broad range helper T cell epitopes. Administration of the plasmids as a vaccine to a vertebrate subject provides an immune response to the subject's endogenous CETP and modulation of CETP activity, leading to prevention or reversal of various manifestations of heart disease. The vaccines provide an advantageous strategy for the prevention or treatment of atherosclerosis.
Patent AT-E206568-T1 (AT)
Inventor: MAVRETIC ANTON
IPC: H03H7/40
Filed: 1997-06-11
Granted: 2001-10-15
Abstract: An apparatus for matching the variable impedance of a load with the fixed impedance of a radio frequency (RF) power generator to provide maximum power transfer. The impedance matching network further allows an RF power generator to vary the frequency of the voltage applied to a load, e.g., a plasma chamber as may be utilized in semiconductor or flat panel plasma display manufacturing processes. The impedance matching network further utilizes fixed solid state components to adjust the impedance of the attached load to provide maximum power transfer between the generator and the load. A parallel switched capacitor network is controlled by an electrical switching means such as PIN diodes to turn fixed capacitors on or off. A means for varying the frequency of the applied voltage is used to match the impedance of the load with the impedance of the RF power generator within milliseconds.