baber/WOPTO huggingface dataset:
Patent DE-69229781-T2 (DE)
Inventor: SNORRASON ERNIR
IPC: A61K31/365
Filed: 1992-05-14
Granted: 2000-01-05
Abstract: The use of a pharmaceutically acceptable cholinesterase inhibitor or a prodrug therefor for counteracting the sedative, hypnotic or respiratory depressive effects of benzodiazepines, substantially without interfering with the anxiolytic, antipsychotic, anticonvulsant, and muscle relaxant activity of benzodiazepines, especially the benzodiazepines used for treatment of diseases where the sedative, hypnotic or respiratory depressive effects are undesirable, such as diseases selected from the group consisting of anxiety, anxiety neurosis, anxiety reactions, panic reactions, schizophrenia, affective or schizoaffective type schizophrenia, borderline psychosis, agitating endogene depressions, hyperactivity in children, and muscle spasms; the use of a pharmaceutically acceptable cholinesterase inhibitor or a prodrug therefor for the treatment of schizophrenia, in particular affective or schizoaffective type schizophrenia. The acetyl cholinesterase is preferably one that acts substantially selectively at nicotinic receptor sites, and which has selectivity for acetyl cholinesterase opposed to butyryl cholinesterase, e.g. galanthamine or a galanthamine derivative.
Patent DE-69404322-T2 (DE)
Inventor: DALTON Christopher
IPC: A61P25/28
Filed: 1994-10-04
Granted: 1997-10-30
Abstract: This invention relates to the enhancement of memory and cognition and the treatment of Alzheimer's disease and Wernicke-Korsakoff syndrome by administration of 3-aryl-4-alkyl and 4,5-dialkyl-4H-1,2,4-triazoles of formula (I) wherein R1 and R2 independently represent hydrogen, halogen, trifluoromethyl, nitro, C1-4 lower alkyl or C1-4 lower alkoxy, or together, R1 and R2 represent -CH=CH-CH=CH-, forming a 1- or 2-naphthylenyl ring system; R3 represents hydrogen or C1-4 lower alkyl; and R4 represents C1-4 lower alkyl, benzyl, or benzyl substituted by one or two groups selected from halogen, trifluoromethyl, nitro, C1-4 lower alkyl or C1-4 lower alkoxy.
Patent DE-69404676-T2 (DE)
Inventor: TORRE EARL
IPC: C04B35/622
Filed: 1994-11-10
Granted: 1998-03-05
Abstract: Shaped ceramic articles can be obtained by forcing a ceramic precursor gel into a belt provided with apertures corresponding to the shapes of the desired articles, freezing the gel in the apertures so that they can be removed without losing structural integrity and then removing the frozen articles from the belt and drying and firing them to produce the desired shaped ceramic articles.
Patent DE-69413213-T2 (DE)
Inventor: ASHWELL MARK
IPC: A61P25/00
Filed: 1994-03-17
Granted: 1999-05-06
Abstract: PCT No. PCT/GB94/00539 Sec. 371 Date May 24, 1995 Sec. 102(e) Date May 24, 1995 PCT Filed Mar. 17, 1994 PCT Pub. No. WO94/21610 PCT Pub. Date Sep. 29, 1994Piperazine derivatives of formula (I) and their salts are 5-HT1A binding agents and may be used, for example, as anxiolytics. In the formula, R, R2 and R4 are hydrogen or lower alkyl, R1 is mono- or bicyclic aryl or heteroaryl, R3 is lower alkyl or cycloalkyl, A is an alkylene chain and X is -CO-. -CR5OH- (where R5 is hydrogen, lower alkyl or cycloalkyl), -S-, -SO- or -SO2- or X can also be -(CH2)n- (where n is 0, 1 or 2) when R3 is cycloalkyl.    <IMAGE>  (I)
Patent DE-69425750-T2 (DE)
Inventor: FOLDVARI MARIANNA
IPC: A61Q19/00
Filed: 1994-07-28
Granted: 2001-04-26
Abstract: A biphasic multilamellar lipid vesicle comprising a plurality of spaced apart lipid bilayers that include a liposome-forming component and optionally a biologically active agent entrapped within the lipid bilayers. The lipid vesicle also comprises peripheral aqueous solution compartments formed between the lipid bilayers and a central lipophilic core compartment substantially at the center of the multilamellar lipid vesicle.
Patent DE-69432145-T2 (DE)
Inventor: PINCHASIK GREGORY
IPC: B21F3/02
Filed: 1994-03-11
Granted: 2004-01-15
Abstract: A stent (220) made of a shape memory alloy, such as nitinol, comprises a coiled wire having at least one section wound in one sense and at least one section wound in the opposite sense. The stent (220) is deployed by being tightly wound on a catheter (24) and immobilized thereon at its respective end points (42) as well as at at least one intermediate point, such as points (140) where the winding changes direction. The immobilization may be by means of threads (28) engaged by wires (132, 133) through bores (232, 233) in the catheter interior. These threads (28) can be selectively released by successive removal of the wires (132, 133) so that the intermediate points (142) of the stent, for example, may be released before the end points (42) thereof. The threads (28) can alternatively be released by melting upon heating, or by breaking e.g. by using electrically conducive wires and applying current thereto. <IMAGE>
Patent DE-69432515-T2 (DE)
Inventor: MARCOCCIA BRUNO S
IPC: D21C9/02
Filed: 1994-02-25
Granted: 2004-02-05
Abstract: A single vessel digester system for digesting cellulosic fibrous material comprises a substantially upright vessel (221) having a top (220) and bottom (222) with a slurry of comminuted cellulosic material to be digested introduced adjacent the top (220), and pulp withdrawn adjacent the bottom (222); the vessel having a continuous cooking zone disposed at a first level of said digester (221), and including a first screen (225) for removing liquor from the cooking zone and a cooking circulation loop (230, 235, 238, 239) associated with said first screen (225) for circulating removed liquor to the interior of said digester (221) near the vicinity of said first screen (225); and an extraction screen (245) with extraction conduit (246) located at a second vertical level in said vessel (221), below said first level, and having means for adding dilution liquid (241; 242), having a lower dissolved organic material concentration than the liquor removed in said cooking circulation loop (230, 235, 238, 239), to said cooking circulation loop (230, 235, 238, 239), to reduce the concentration of DOM in the digester and thereby increase the strength of the pulp so-produced.
Patent DE-69434515-T2 (DE)
Inventor: OSHLACK BENJAMIN
IPC: A61K47/38
Filed: 1994-06-14
Granted: 2006-07-06
Abstract: The invention concerns controlled release oxycodone dosage forms comprising a multiparticulate system substrate comprising an amount of an oxycodone salt, the substrate being coated with an aqueous dispersion of at least one hydrophobic polymer, whereby the coating provides controlled release, the substrate including an additional dose of an oxycodone salt included in either the controlled release coating or in an additional overcoating coated on the outer surface of the controlled release coating, whereby the dosage forms, comprising the cured, coated substrate, comprise an effective amount of an oxycodone salt and provide a therapeutic effect for at least 12 hours when administered to a patient.
Patent DE-69502881-T2 (DE)
Inventor: ARDUIN JOEL
IPC: A63C5/075
Filed: 1995-04-20
Granted: 1998-10-15
Abstract: The interface has two bases (14,21) under the back and front bindings (12,13) which are joined to the ski (1). Support plates under the toe and heel of the sole of the boot move vertically to capture the variations of force exerted by the boot. The support plates are on plates (10,20) which are joined by a bar (38). One end of this is articulated (32) to the end of the front plate (20). Its other end is articulated (37) on an oblique rod (35), articulated on a bearing (36) joined to the ski, on which the back support plate (13) rests. <IMAGE>
Patent DE-69522687-T2 (DE)
Inventor: MANDEVILLE HARRY
IPC: A61K9/52
Filed: 1995-05-24
Granted: 2002-06-20
Abstract: A method for removing bile salts from a patient by ion exchange by administering to the patient a therapeutically effective amount of one or more highly crosslinked polymers characterized by a repeat unit having the formula    <IMAGE>  (1)  or copolymer thereof, where n is an integer; R1 is H or a C1-C8 alkyl group; M is   <IMAGE>   or -Z-R2; Z is O, NR3, S, or (CH2)m; m=0-10; R3 is H or a C1-C8 alkyl group; and R2 is   <IMAGE>   where p=0-10, and each R4, R5, and R6, independently, is H, a C1-C8 alkyl group, or an aryl group, the polymers being non-toxic and stable once ingested.
Patent DE-69524319-T2 (DE)
Inventor: RENTSCH WOLFGANG
IPC: G01P3/44
Filed: 1995-09-04
Granted: 2002-07-18
Abstract: The tachometer comprises a microphone for disposition next to the exhaust of the vehicle and an accelerometer for disposition adjacent to its engine. A selected one of the outputs is connected to an ADC which provides digital samples to a central processing unit. Also, the ripple from the battery is sampled and provided to the CPU. The CPU calculates a constant representing the relationship of the frequencies of the ripple samples and the mechanical samples and responds to the ripple samples and the constant to provide output signals corresponding to the speed of the engine. The speed is displayed. <MATH>
Patent DE-69531859-T2 (DE)
Inventor: TERMIN L
IPC: A61L27/36
Filed: 1995-02-17
Granted: 2004-07-29
Abstract: This invention is directed to prostheses, which, when implanted into a mammalian host, serve as a functioning replacement for a body part, or tissue structure, and will undergo controlled biodegradation occurring concomitantly with bioremodeling by the host's living cells. The prosthesis of this invention, in its various embodiments, thus has dual properties: first, it functions as a substitute body part and second, it functions as a bioremodeling template for the ingrowth of host cells. <IMAGE> <IMAGE> <IMAGE>
Patent DE-69535384-T2 (DE)
Inventor: WEININGER SUSAN
IPC: C12N15/09
Filed: 1995-12-07
Granted: 2007-09-13
Abstract: Detecting and localising specific nucleic acid sequences in a sample involves the use of Probe Nucleic Acids, the production of nucleic acid binding regions and the use of nucleic acid Target Binding Assemblies to detect and localise specific Target Nucleic Acids. The detection and localisation of the Target Nucleic Acid is accomplished even in the presence of nucleic acids which have similar sequences. The method provides for a high degree of amplification of the signal produced by each specific binding event. In particular, methods and compositions are presented for the detection of HIV and HPV nucleic acid in samples. These methods and compositions find use in diagnosis of disease, genetic monitoring, forensics, and analysis of nucleic acid mixtures.
Patent DE-69602203-T2 (DE)
Inventor: AZIMA HENRY
IPC: H04R7/06
Filed: 1996-09-02
Granted: 1999-09-16
Abstract: A panel-form loudspeaker (81) having a distributed mode acoustic radiator (2, 4) and a first transducer (9) coupled to the radiator (2) to excite distributed mode resonance in the radiator, characterised by a second transducer (9) coupled to vibrate the radiator (14).
Patent DE-69602414-T2 (DE)
Inventor: LOUSSAYRE FREDERIC
IPC: C08G12/00
Filed: 1996-11-28
Granted: 1999-10-07
Abstract: Melamine-formaldehyde resins for impregnation with molar ratio F:NH2 = 0.45-0.6 are obtained in aqueous solution by condensation in alkaline medium at 80-120 degrees C until test sample becomes cloudy at 20-40 degrees C at 2:1 dilution. Resins contain 0.1-5 wt.% of at least one 4-12C cyclic saturated ketone as stabiliser. Also claimed is method for preparation of resins.
Patent DE-69605856-T2 (DE)
Inventor: LESIEUR DANIEL
IPC: A61P25/28
Filed: 1996-05-30
Granted: 2000-07-20
Abstract: Alkoxy aryl derivatives of formula (I), their enantiomers and diastereoisomers, and their salts, are new. R1 = 1-4C alkylene chain, opt. substd by alkyl, OH, alkoxycarbonyl or carboxyl; R2 = H or alkyl; R3 = a group R31 or R32; R31 = -C(=X)-(CH2)n-R5; R32 = -C(=X')-NH-(CH2)m-R6; n = 0-3; X = S or O; R5 = H, opt. substd alkyl, alkenyl, alkynyl, opt. substd cycloalkyl, or opt. substd dicycloalkylalkyl; X' = O or S; m = 0-3; R6 = H, opt. substd alkyl, alkenyl or alkynyl, or may also be opt. substd cycloalkyl or opt. substd dicycloalkylalkyl when X' = O; A = alkyl or A'; A' = substd. alkyl, alkenyl, or alkynyl; R = opt. substd. alkyl, alkenyl, alkynyl, opt. substd cycloalkyl, opt. substd cycloalkylalkyl, opt. substd aryl, opt. substd aralkyl, opt. substd diarylalkyl, cycloalkenyl or cycloalkenyl alkyl; Y with the benzo group to which it is attached = a group Y'; Y' = naphthalene, benzofuran, benzothiophene, or indole if A = A', or Y = naphthalene if A = alkyl; Y' may be partially hydrogenated; with the provisos that: substituents on alkyl are one or more halo, OH, or alkoxy; substits on cycloalkyl, cycloalkylalkyl and dicycloalkylalkyl are one or more of halo, OH, alkyl, alkoxy or oxo; substits on aryl, arylalkyl and diarylalkyl are one or more halo, OH, alkyl, haloalkyl, or alkoxy; alkyl, alkoxy, alkenyl and alkynyl = up to 6C; cycloalkyl and cycloalkenyl = 3-8C; and aryl = phenyl or naphthyl.
Patent DE-69605898-T2 (DE)
Inventor: KUPER TOM
IPC: A61J1/14
Filed: 1996-02-26
Granted: 2000-10-05
Abstract: The invention relates to a system for the administration of a medical substance. The system comprises a substance reservoir which has a metering opening which is sealed by a sealing element. A metering line system is detachably connected to a relatively rigid, annular coupling element of the reservoir. The metering line system comprises a flexible channel section with a penetration means located therein. By shortening the channel section, the penetration means can be pushed through the seal of the reservoir after fixing the metering line system to the reservoir. A reliable and relatively simple coupling is obtained by means of a coupling bush which has an annular wall and a base surface with a central opening. The flexible channel section forms one end of the metering line system and extends through the opening of the coupling bush and terminates in a flexible sealing flange. By tightening the coupling bush against the coupling element of the reservoir, the flexible sealing flange is pushed hermetically into contact with the coupling element of the reservoir. The invention further relates to a metering line system and a reservoir for use in a system of this type.
Patent DE-69606559-T2 (DE)
Inventor: FARISON K
IPC: B65D81/07
Filed: 1996-11-08
Granted: 2000-08-24
Abstract: There is provided an inflatable cushion inflated through a single inflation valve. A pair of inflated panels held in place by at least one tie strap connecting the panels rest beneath each end of the bottom of an article to be protected. The cushion has a pair of inflatable end chambers interconnected to the bottom panels and a pair of inflatable side chambers interconnected to the end chambers, which when inflated protect the ends and sides of the article. This is facilitated by internal openings which allow the inflated panels to easily bend underneath the ends of the article and around the corners. There are recesses at each corner which extend from each corner of one internal opening toward a peripheral edge of the cushion to provide a wedge-like portion of the side chambers. In one of the embodiments, an additional pair of internal openings facilitates a pair of top inflatable chambers interconnected to the end chambers to rest on the top of the article. In another embodiment of the present invention, the chamber protecting the upper portion of the article includes a single inflatable chamber which folds across the top of the article. The top chamber has an internal opening in the middle thereof formed by a weld. Extending inwardly from the weld are portions of each thermoplastic sheet which remain after the cushion has been cut and adapted to hold a thin article.
Patent DE-69607129-T2 (DE)
Inventor: DEL GROSSO LAMBERTO
IPC: F23N3/08
Filed: 1996-06-25
Granted: 2000-07-13
Abstract: A device (1) for optimizing the efficiency of a gas-fired heat generator comprising a burner positioned within a combustion chamber provided with a fan for evacuating burnt gases, the fuel reaching said burner via a feed pipe in which there is positioned an electrically powered pressure regulator, said regulator being controlled to vary the gas flow rate to the burner by electrical signals generated by a control unit of the heat generator. The device comprises fan command and control means (2) which measure the electrical control signals (VREF) of the pressure regulator, said signals (VREF) being compared with a reference signal (VR) to generate a control signal for the fan, the rotational speed of this latter being modified on the basis of the control signals (VREF) which reach the pressure regulator. <IMAGE>
Patent DE-69608372-T2 (DE)
Inventor: ZANOTTO UGO CESARE
IPC: B23Q1/01
Filed: 1996-06-28
Granted: 2000-12-28
Abstract: Machine-tool (1) for performing machining operations on workpieces (10) of undefined length such as sections, bars and the like, comprising a fixed support (2) having mounted on it the working head (3) which consists of a surface (5) perpendicular to the direction (X) of feeding of the workpiece, a first arm (6) perpendicularly mounted on said surface and translatable thereon by means of guides (6b) located on the surface itself, and a second arm (7) carrying the tool (8), perpendicularly mounted on said first arm (6) and movable with respect thereto, said working head being rotationally connected to the support (2) by means of an element (4) which can be rotated by associated actuating means (4b), said element (4) for rotationally connecting the head (3) and said support (2) being provided moreover with associated openings (4a, 2a) for passage of the workpiece (10) itself fed towards the working head (3) by associated translating means (9a, 9) acting in the said feeding direction (X) <IMAGE>
Patent DE-69611209-T2 (DE)
Inventor: ONO TATSUO
IPC: E01D21/00
Filed: 1996-07-19
Granted: 2001-04-26
Abstract: Disclosed is a shore which has a durability with respect to loads not only in a longitudinal direction and a lateral direction but also in a lengthwise direction, and which can be automatically folded without requiring extra work. The shore comprising a pair of front and rear fixed frames 10, a pair of left and right foldable reinforcing frames 11 interposed between both left and right ends of each of the fixed frames, and a pair of front and rear floor plates 12 whose proximal ends are pivotally mounted to an inner intermediate portion of each of the fixed frames, characterized in that said reinforcing frame comprises a folding handrail column 13 whose proximal end is pivotally mounted between upper ends of the fixed frame, four expandable braces 14 whose proximal ends are pivotally mounted to upper and lower ends of each of the fixed frames and obliquely extending toward the inner intermediate portion, a support member 15 comprising a flange 16 for pivotally mounting an extreme end of each brace 14 and a guide tube 17 provided on the back surface of the flange, a support rod 18 whose proximal end is secured to the intermediate portion of said handrail column 13 and whose lower end is secured into or slidably and selectively inserted into said guide tube, and a bracket 19 provided at the lower end of said support rod and for rotatably connecting the extreme end of said floor plates. <IMAGE>
Patent DE-69613044-T2 (DE)
Inventor: MANCA DOMENICO
IPC: B04B1/02
Filed: 1996-01-10
Granted: 2002-02-14
Abstract: The present invention relates to a reduced size apparatus (1) for the centrifugal separation, comprising a housing (2), motor means (3) coupled to said housing (2) and provided with a rotary shaft (6), cartridge means (9; 13), provided within said housing (2) and coupled with said rotary shaft (6), at least a first feeding channel (12) for the liquid to be undergo to the centrifugal treatment from outdoor within said cartridge means, at least a second channel (7) through said rotary shaft (6), communicating with said cartridge means (9; 13), and at least a third channel (8) for the ejection of the liquid, communicating with said second channel (7). <IMAGE>
Patent DE-69620320-T2 (DE)
Inventor: FAVRE ROGER
IPC: B23D51/14
Filed: 1996-08-22
Granted: 2002-10-02
Abstract: The saw has a U-shaped frame with an identical blade holder at each end. Each holder consists of a block (35) with a lengthwise passage of the same cross-sectional dimensions as the blade (5) to guide and centre the blade end inserted into it, and has a locking screw (37) situated perpendicular to the passage to fix the blade in place. In a variant of the design the block can incorporate a second locking screw, situated opposite the first one to hold the blade between the tips of the two screws. Each blade holder can be attached to the T-section end (41) of the saw frame by one of the locking screws. The saw frame can be made from tubing, and each blade holder block is of light alloy. The saw handle is of a plastic material, foam-covered to prevent slip.
Patent DE-69621117-T2 (DE)
Inventor: FASCE XAVIER
IPC: H01R4/24
Filed: 1996-05-02
Granted: 2002-10-31
Abstract: The modular jack includes two self-stripping contacts (1,2), each provided with two slots and being inserted in a plastic body (3). The body presents a rotating plastic lid (4) which can turn about an axis (5) parallel to the group of contacts. Two pairs of blades (61-64) are actuated when the lid is shut The blades push extremities of telephone line conductors into the slots corresponding to each contact. An elastic clip (7) locks the lid in the closed position thus securing the connection.
Patent DE-69628632-T2 (DE)
Inventor: SHIKINAMI YASUO
IPC: B29C43/16
Filed: 1996-09-13
Granted: 2004-04-29
Abstract: A high bending strength and high density material for osteosynthesis, which comprises a biodegradable and bioabsorbable crystalline thermoplastic polymer material, and a high strength implant material, comprising a composite material in which a bioceramics powder of from 0.2 to 50  mu m in particle size is dispersed in the polymer material, wherein crystals of the polymer material are pressure-oriented not in a uni-axial direction but basically in parallel with a plurality of reference axes; and a production method by pressure orientation, which comprises preparing in advance a biodegradable and bioabsorbable crystalline thermoplastic polymer material or a dispersed mixture of the polymer material and a bioceramics powder and melt-molding it into a pre-molded material which is then press-charged at a cold temperature into a cavity of a closed type forming mold, thereby obtaining an oriented molding. Since the osteosynthesis and implant materials are dense and high strength oriented moldings having less anisotropy in which crystals are oriented in parallel with a plurality of reference axes, excellent ideal biomaterials can be provided which have appropriate hydrolysis property, can maintain sufficient strength during a period required for bone union and are degraded and absorbed at such a rate that they do not induce inflammatory reactions after healing of the fractured bones so that re-operation is not required. <IMAGE>
Patent DE-69632467-T2 (DE)
Inventor: KOTILAINEN OLLI
IPC: G09F17/00
Filed: 1996-09-06
Granted: 2005-05-12
Abstract: A flag raising and lowering device (11) for raising the flag (18) up the flagpole (10) and for lowering the flag, the said device comprising a protective tube (12) for the flag and a driving motor (13). The device is an accessory separate from the actual flagpole, which device is located on the lower part of the flagpole, on its side. The accessory includes a protective tube (12) for the flag and a driving motor (13). The halyard (15) is passed at the upper end of the flagpole via the flagpole's own original sheave (17) and at the lower end of the flagpole via the sheave (14) of the protective tube and the driving motor (13), so that by moving the halyard, the flag (18) can be pulled inside and out of the protective tube.