baber/WOPTO huggingface dataset:
Patent CA-2220964-C (CA)
Title: Alphavirus rna replicon systems
Inventor: JOHNSTON ROBERT E
IPC: A61K39/00
Filed: 1996-05-21
Granted: 2011-09-13
Abstract: The present invention provides a helper cell for expressing an infectious, replication defective, alphavirus particle in an alphavirus-permissive cell. The helper cell includes (a) a first helper RNA encoding (i) at least one alphavirus structural protein, and (ii) not encoding at least one alphavirus structural protein; and (b) a second helper RNA separate from the first helper RNA, the second helper RNA (i) not encoding the alphavirus structural protein encoded by the first helper RNA, and (ii) encoding the at least one alphavirus structural protein not encoded by the first helper RNA. Preferably, the helper cell is co-transfected with a replicon RNA encoding an alphavirus packaging segment and an inserted heterogeneous RNA, such that all of the alphavirus structural proteins assemble together into alphavirus particles in the cell, with said replicon RNA packaged therein.
Patent CA-2221771-C (CA)
Title: Use of tropolone derivatives as inhibitors of the enzyme inositol monophosphatase
Inventor: DENARO MAURIZIO
IPC: A61K31/19
Filed: 1996-05-20
Granted: 2007-09-18
Abstract: The present invention concerns the use of puberulic or puberulonic acid as inhibitors of the enzyme inositol monophosphatase (EC 3.1.3.25) and thus useful in the treatment of maniac or depressive symptoms.
Patent CA-2223593-C (CA)
Inventor: MCDONOUGH JAMES M
IPC: F23Q2/16
Filed: 1996-06-03
Granted: 2004-12-14
Abstract: A selectively actuatable lighter device (10) is disclosed which includes a body (12) defining a reservoir for containing a combustible gaseous medium such as butane, and having a valve (20, 21) arranged to be selectively actuated between a normally closed position and an open position and a position which permits the exit of the gaseous medium. Such a lighter can selectively produce sparks at a location proximate to the gaseous medium exit to ignite the gaseous medium. Such lighter device embodies a resiliently releasable latch (16) which normally prevents actuation of a valve actuator (14) to the open position thereby preventing actuation of the valve. The latch is selectively movable to a position out of interference (Figure 14) with the valve actuator (14) so that the gaseous medium may be released and ignited by the sparks. The latch is resiliently structured and mounted such that once the flame is produced and the valve actuator is released, the latch returns to its closed or latched position.
Patent CA-2229699-C (CA)
Title: Method and apparatus for light transmission
Inventor: CROSS DAVID M
IPC: F21V21/00
Filed: 1998-02-16
Granted: 2004-10-19
Abstract: A method and apparatus for light transmission adapted for use in a reflective belt, safety vest, or similar devices requiring visibility of a bright and/or reflective material where a light source of one or more lighting elements is positioned to transmit light along a self-supporting elongated light transmitting member of a hot-melt adhesive thermoplastic material and a flashing circuit for the light source which includes a battery pack or any other power source convertible to D.C. voltage. The hot-melt adhesive is of a high clarity, highly flexible material which transmits light in a highly visible manner within an elongated casement of material formed of a light-colored backing material and a front strip of a translucent material adapted to transmit the light driven along the member by the light-emitting source. Any light-emitting source, either visible or invisible would be suitable for the transmitting device. Similarly, the casement of material, elongated members, light-emitting sources and circuit and D.C. power source could be mounted on either the front and/or rear panel of a safety vest where the vest is desirable for high visibility in darkness or dimly lit situations.
Patent CA-2232869-C (CA)
Title: Chewing gum manufacture using high efficiency continuous mixing
Inventor: SONG JOO H
IPC: A23G4/06
Filed: 1995-09-13
Granted: 1999-11-30
Abstract: A method is provided for the total manufacture of chewing gum on a continuous basis.  The method uses a continuous high efficiency mixer which is configured for the total manufacture of a wide variety of chewing gum products.  Pursuant to the present invention, a preblend of glycerin and syrup is added to the mixer.
Patent CA-2238301-C (CA)
Inventor: LOBLICK NORTON MARCUS
IPC: G01M3/20
Filed: 1998-05-22
Granted: 2006-01-24
Abstract: A smoke generating apparatus includes a housing having an interior cavity.  A heated substrate is disposed within the interior cavity of the housing.  A reservoir is provided to hold smoke generating liquid.  An atomizing nozzle is disposed within the interior cavity of the housing.  The nozzle has an inlet end and an outlet end.  The outlet end points toward the heated substrate, such that fluid medium discharged through the outlet of the nozzle strikes the heated substrate.  The inlet end of the nozzle is coupled to a source of gas under pressure.  A liquid flow passage is provided which connects the nozzle with the reservoir.  A flow of gaseous medium through the nozzle atomizes smoke generating liquid drawn from the reservoir.
Patent CA-2239026-C (CA)
Title: Appareil destine au traitement en continu d'une matiere particulaire et procede correspondant
Inventor: TOUBORG JORN
IPC: C04B7/45
Filed: 1996-12-17
Granted: 2005-04-05
Abstract: Cette invention concerne un procédé destiné au traitement en continu d'une matière particulaire, du type farine crue de ciment, dans un appareil comportant un réacteur stationnaire (6) ayant la structure d'un lit fluidisé avec giclage, vers lequel la matière est amenée et traitée dans un lit suspendu par du gaz qui, par l'intermédiaire d'un orifice d'admission (21) de gaz disposé de façon centrale, est injecté au niveau du bas du réacteur (6) et s'écoule suivant une direction ascendante à travers le réacteur (6), et d'où la matière est rejetée par un orifice (21) ménagé en bas du réacteur (6). Les dimensions, les paramètres de fonctionnement du réacteur (6, 21) ou les volumes des appareils reliés (8a) sont sélectionnés et régulés de telle sorte que, en cours de fonctionnement, le lit subit, dans le réacteur (6), des vibrations ascendantes et descendantes ayant une amplitude telle qu'une quantité de la matière du lit correspondant à la quantité de matière ayant fraîchement alimenté le réacteur, lorsque le lit se trouve au niveau de sa position la plus basse, est amenée à l'intérieur d'une zone (22), dans laquelle la vitesse du flux de gaz est inférieure à la vitesse minimale requise pour suspendre les particules du lit, et chute de ce fait à travers le flux de gaz sortant du réacteur (6).
Patent CA-2240327-C (CA)
Inventor: ISHII DOUGLAS N
IPC: A61P25/28
Filed: 1996-12-11
Granted: 2005-07-12
Abstract: The invention concerns a method for effecting changes in the central nervous system, including treatment of brain and spinal cord disorders or diseases, by parenteral administration of insulin-like growth factors I (IGF-I) or insulin-like growth factor II (IGF-II).
Patent CA-2246186-C (CA)
Title: Methods of completing and producing a subterranean well and associated apparatus
Inventor: FREEMAN AUSTIN
IPC: E21B23/06
Filed: 1998-09-02
Granted: 2006-01-24
Abstract: A disclosed method and associated apparatus provide convenient and accurate control of rates of fluid flow within a subterranean well. In one described embodiment, an apparatus has multiple tubing strings installed within multiple wellbores intersecting formations or intervals into, or from which, fluid is to be flowed. A remotely controllable flow regulating device is provided for each of the formations or intervals to regulate the rate of fluid flow through its associated tubing string. In another described embodiment, a single tubing string is utilized with multiple remotely controllable flow regulating devices interconnected therein.
Patent CA-2246208-C (CA)
Inventor: JANY JOHN R
IPC: A01N43/66
Filed: 1998-08-31
Granted: 2007-06-19
Abstract: Disclosed is a stable gel-like slurry having a pH of about 6.5 to about 8.5 which is a mixture of water and about 20 to about 50 wt% sodium cyanurate. Also disclosed is a method of making a water-monosodium cyanurate hydrate gel-like slurry. A slurry is formed in water of about 20 to about 50 wt% cyanuric acid. Sodium hydroxide is added to the slurry in an amount of about 90 to about 100% of stoichiometric over a period of about 40 minutes. Water can be disinfected by adding to the water an amount of water-monosodium cyanuric hydrate gel-like slurry according to this invention equivalent to a concentration of cyanuric acid in the water of about 25 to about 150 ppm and an amount of a source of chlorine sufficient to maintain a concentration of chlorine in the water between about 0.1 and about 5.0 ppm.
Patent CA-2252402-C (CA)
Inventor: WILKENING ROBERT R
IPC: A61K31/397
Filed: 1997-04-21
Granted: 2002-12-24
Abstract: Agents antibactériens à base de carbapénem dans lesquels le noyau carbapénem est substitué en position 2 par un naphtosultame lié par l'intermédiaire d'un groupe CH¿2?. Le naphtosultame est lui-même substitué par divers groupes de substitution, dont au moins un groupe cationique. Ces composés répondent à la formule (I). Des compositions pharmaceutiques et des procédés d'utilisation sont également décrits.
Patent CA-2257172-C (CA)
Title: Dissolvable oxides for biological applications
Inventor: SAARINEN NIILO
IPC: A61K9/06
Filed: 1997-05-29
Granted: 2005-04-12
Abstract: The present invention is concerned with controllably dissolvable silica- xerogels prepared via sol-gel process and their use. Specifically, the invention is concerned with a delivery device comprising controllably dissolvable silica-xerogel into which structure a biologically active agent is incorporated. The invention is further concerned with pharmaceutica l preparations comprising said delivery device. Further, the invention is directed to medical devices for orthopedic and surgical purpose s comprising controllably dissolvable silica-xerogels, which may further comprise a biologically active agent.
Patent CA-2257729-C (CA)
Title: Model gun with automatic bullet supplying mechanism
Inventor: KUNIMOTO KEIICHI
IPC: F41B11/721
Filed: 1999-01-06
Granted: 2001-10-09
Abstract: A model gun with automatic bullet supplying mechanism comprises a pressure accumulating chamber from which a gas leading passage extends, a slider movable along a barrel structure, a pressure receiving portion fixed in the slider at the back of the barrel structure, a movable member provided with first and second inner spaces and arranged at the back of a bullet holding chamber, and a movable valve provided in the first inner space formed in the movable member. The movable valve is operative selectively, during a period in which the gas leading passage is connected with the first and second inner spaces formed in the movable member, to cause gas derived through the gas leading passage from the pressure accumulating chamber to act through the first inner space on a sham bullet in the bullet holding chamber and to shut off gas flow to the bullet holding chamber through the first inner space from the gas leading passage so that the gas derived through the gas leading passage from the pressure accumulating chamber acts through the second inner space on the pressure receiving portion to cause first the pressure receiving portion to move back in company with the slider and then the movable member also to move back for making preparations for supplying the bullet holding chamber with a sham bullet from a magazine.
Patent CA-2260938-C (CA)
Inventor: BRUSH HENRY T
IPC: C08J3/20
Filed: 1997-02-27
Granted: 2003-05-06
Abstract: It has been discovered that the incorporation of gases, especially fluorinat ed gases such as perfluorocarbons, into microparticles formed from the combination of a natural or synthetic polymer and lipid have significantly enhanced echogenicity as compared with microparticles not including the lipi d. Compounds other than lipids which are hydrophobic and limit the penetration and/or uptake of water into the microparticles can also be incorporated into  the microparticles to enhance echogenicity. In the preferred embodiment, the  polymers are synthetic biodegradable polymers. The microparticles are manufactured with a diameter suitable for the targeted tissue to be imaged, for example, with a diameter of between 0.5 and 8 microns for intravascular administration, and a diameter of between 0.5 and 5 mm for oral administrati on for imaging of the gastrointestinal tract or other lumens. Preferred polymer s are polyhydroxy acids such as polylactic acid-co-glycolic acid, most preferably conjugated to polyethylene glycol or other materials inhibiting uptake by the reticuloendothelial system (RES). The most preferred lipids ar e phospholipids, preferably dipalmitoylphosphatidylcholine (DPPC), distearoylphosphatidylcholine (DSPC), diarachidoylphosphatidylcholine (DAPC) , dibehenoylphosphatidylcholine (DBPC), ditricosanoylphosphatidylcholine, dilignoceroylphatidylcholine (DLPC), incorporated at a ratio of between 0.01 - 30 (w lipid/w polymer), most preferably between 0.1-10 (w lipid/w polymer). Microparticles for imaging using other detectable agents can be similarly manufactured.
Patent CA-2268524-C (CA)
Inventor: KREITZER JOHN T
IPC: A61F5/56
Filed: 1997-11-26
Granted: 2005-10-18
Abstract: This invention is a nasal dilator (20) for dilating a first nasal passage and a second nasal passage of a nose, including an elastic element (32) having a first end (30) and a second end (32), the elastic element movable toward an expanded configuration wherein the length of the elastic element (32) increases, and biases to a retracted configuration wherein the length of the elastic element (32) is reduced. The nasal dilator (10) further includes an adhesive (42') carried proximate the first end (30) for attaching the first end (30) to an outer wall of the first nasal passage, and an adhesive (42') carried proximate the second end (32) for attaching the second end (32) to an outer wall of the second nasal passage.
Patent CA-2273305-C (CA)
Inventor: VESTERLUND INGMAR
IPC: B23B41/00
Filed: 1999-05-28
Granted: 2007-08-21
Abstract: The invention relates to a method for drilling holes in the shell of a paper machine cylinder, with said cylinder being unremoved from its operating position in a paper machine, in which method is utilized a multispindle drilling apparatus (1) equipped with a facility of controlling the distance between the drill centers of the adjacent drilling modules (7). The multispindle drilling apparatus uses drilling modules (7) of at least two spindle heads, whereby the mutual distance of the spindle shaft centers (19, 19') in each drilling module is adjusted by rotating the spindle heads of at least one drilling module about the intermediate shaft (15, 15') of the drilling module. The invention also concerns a compatible apparatus.
Patent CA-2277002-C (CA)
Inventor: NALWA VISHVJIT SINGH
IPC: G02B27/14
Filed: 1999-07-08
Granted: 2002-07-23
Abstract: A compact high resolution omnidirectional or panoramic viewer has several cameras with a common virtual optical center. The field of view of each of the cameras is arranged to form a continuous 360 degree view of an area when taken as a whole. The cameras are positioned so that they each view a different reflective surface of a polyhedron such as a pyramid. This results in each camera having a virtual optical center positioned within the pyramid. The cameras may be positioned so that their virtual optical centers are offset from each other. The offsets produce narrow blind regions that remove image distortions received from the edges of the pyramid's reflective surfaces. The reflective pyramids may be stacked base to base or nested within each other to produce a more compact panoramic viewer. Using two or more reflective pyramids in such close proximity permits using many cameras with the same virtual optical center. Using many cameras divides a large viewing area into many smaller areas where an individual camera views each smaller area. Since each camera views a smaller area, increased resolution is provided to the user.
Patent CA-2277114-C (CA)
Inventor: JESSE GERHART
IPC: E05D11/10
Filed: 1999-07-07
Granted: 2004-06-01
Abstract: A door checking apparatus for an automobile comprising an array of needle bearings held in contact with a bearing surface comprising axially oriented grooves, by means of a resilient energy storage device; a cylindrical cage coaxially adjacent the bearing surface and comprising an axially oriented array of slots arranged to retain the needle bearings; means to impart rotary motion to the cylindrical cage to cause the needle bearings to move relative to the bearing surface to create a torque reaction in response to deflection of the resilient energy storage device as the needle bearings move into and out of the grooves; means to transmit the imparted torque from the bearing surface into an appropriate structure.
Patent CA-2279270-C (CA)
Inventor: JIANG YING
IPC: A61L27/50
Filed: 1998-01-27
Granted: 2007-05-15
Abstract: L'invention concerne des polyesteramides qui renferment des groupes dérivés amino-acides alternant avec des groupes dérivés hydroxyacides. Ces polyesteramides sont utiles à la fabrication de pièces moulées, en particulier les pièces moulées destinées à être utilisées en tant qu'instruments chirurgicaux.
Patent CA-2284449-C (CA)
Inventor: BARRY DAVID C
IPC: A61F2/06
Filed: 1999-10-04
Granted: 2007-01-02
Abstract: An embolic coil deployment system for placing a coil at a preselected site within a vessel of the human body. The deployment system includes a heating element at the distal end of a delivery member and a heat responsive coupling for holding the coil during positioning of the coil and activation means for releasing the coil at a desired position within the vessel.
Patent CA-2284976-C (CA)
Title: Process for preparing single enantiomer narwedine
Inventor: POTTER GERARD ANDREW
IPC: C07D491/10
Filed: 1998-04-08
Granted: 2006-10-17
Abstract: A process for the preparation of substantially single enantiomer (-)-narwedine comprises seeding a solution of racemic narwedine dissolved in a solvent with substantially single enantiomer (-)-narwedine, provided that if an added amine base is present the ratio solvent: added amine base is greater than 15:1.
Patent CA-2297163-C (CA)
Title: Gaba analogs to prevent and treat gastrointestinal damage
Inventor: WATSON WILLIAM PATRICK
IPC: A61K45/06
Filed: 1998-08-18
Granted: 2001-11-20
Abstract: GABA analogs are useful to prevent and treat gastrointestinal damage and ethanol withdrawal syndrome. Preferred treatments employ gabapentin or pregabalin.
Patent CA-2302604-C (CA)
Title: Method of communication with a transportation system
Inventor: FRIEDLI PAUL
IPC: B66B3/00
Filed: 2000-03-28
Granted: 2008-08-05
Abstract: This human-machine interface has a touch screen (1) with a selection of travel destinations at, for example, a university which can be individually selected by touching the screen. The travel destinations are not represented as real locational parameters such as a floor number, for example, but by means of designations. The user selects, for example, the conference room as his travel destination without knowing where the conference room is actually located. A control determines the real locational parameter by means of a table in which, for example, the real locational parameter "Floor 23" is assigned to the designation "Conference Room". The control assigns the desired floor to the elevator car with the best travel conditions and informs the user on the touch screen (1). The information contains the designation of the means of transportation and an indication of the place of boarding.
Patent CA-2306212-C (CA)
Inventor: BANDARA SUMITH V
IPC: H01L29/06
Filed: 1998-10-16
Granted: 2004-03-16
Abstract: Un réseau de pixels (100) de détection détecte le rayonnement infrarouge d'au moins deux longueurs d'onde. Au moins chaque pixel (100) de détection comprend au moins deux piles (110, 120) de détection à puits quantiques différentes, lesquelles sont polarisées à une tension commune (T polarisation).
Patent CA-2310285-C (CA)
Inventor: SCHNEIDER JIM D
IPC: B24D13/10
Filed: 1998-11-30
Granted: 2005-04-19
Abstract: A polymeric foam finishing pad (10) is made by attaching a dense array of individual foam members (11) to a suitable support substrate (14). The member (11) may be individually attached to the substrat e (14) or attached to the substrate (14) by an intermediate foam strip (16) to which the members (11) are integrally joined. The foam members (11) are preferably individually inserted into a support substrate (14) and attached to the substrate by an adhesive layer (35). Each of the foam members (11) is preferably folded and inserted into a preformed opening (46) contained in the support substrate (14), such that each foam member (11) forms a pair of fingers (12) that extend from the front face of the support substrate (14). The outer tip (12) of each foam finger may be slit to define a plurality of contact tips, thereby increasing the amount of surface contact between the finishing pad (10) and the surface being finished.
Patent CA-2317231-C (CA)
Title: Processus de mise en oeuvre d'un reconnaisseur de parole ainsi que reconnaisseur de parole et processus de reconnaissance de la parole associes
Inventor: FRASCA ALESSANDRA
IPC: G10L15/06
Filed: 2000-09-01
Granted: 2008-01-22
Abstract: Cet extrait concerne un procédé de reconnaissance de la parole. Pour mettre en ouvre un système de reconnaissance de la parole dans le cas d'une langue pour laquelle les moyens d'entraînement à la parole sont très limités, la première chose à faire est de mettre sur pied, en fonction des moyens connexes disponibles et à partir d'une pluralité de langues connues, un système de reconnaissance de la parole multilingue. Le système de reconnaissance de la parole pour la langue donnée est ensuite créé par interpolations à partir du système multilingue. Le système de reconnaissance de la parole obtenu de cette façon peut ensuite être raffiné à l'aide des moyens d'entraînement à la parole connexes recueillis en ligne durant son utilisation ultérieure.
Patent CA-2327212-C (CA)
Inventor: PAULY LOU ALLEN
IPC: F02C3/08
Filed: 2000-12-01
Granted: 2003-10-28
Abstract: A centrifuge compression air turbine employing curved radial downward sloping fan blade compressor fan units, which densify the air entering the turbine combustor section, or alternatively when placed within the turbine exhaust air stream, converts the energy in the air exhaust stream leaving into rotational energy.
Patent CA-2331954-C (CA)
Title: Method and apparatus for stabilizing transient control in amplified optical networks
Inventor: FEULNER MATTHIAS RICHARD
IPC: H04B10/29
Filed: 2001-01-22
Granted: 2006-10-31
Abstract: An apparatus and method are described for controlling response to power transients in an optically amplified wavelength division multiplexed (WDM) network when WDM optical channels are added and dropped, during network reconfigurations, during failure events, and so on. In one embodiment, a variable bandwidth filter circuit operates at a first prescribed bandwidth during a first time period io to detect a change in signal power (i.e;., power transient) caused by a transient event, and operates at a second prescribed bandwidth that is less than the first prescribed bandwidth after the first period of time elapses, e.g., .TAU.0 + .DELTA..TAU. to substantially suppress low level signal variations, such as remnants of the power transient. In this way, the power transient related to the actual transient event will be preserved to trigger control circuitry, e.g., amplifier gain control based on input power changes, while the remnants will be filtered out to prevent unwanted responses by the control circuitry, e.g., remnants misinterpreted as actual transient events.