baber/WOPTO huggingface dataset:
Patent PT-1589019-E (PT)
Title: Stereoselective process for the preparation of clopidogrel
Inventor: FRANTISEK JAROSLAV
IPC: C07C209/68
Filed: 2004-04-20
Abstract: Preparation of (2-halophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl) compounds (Ia) or their salts comprises converting benzene derivatives (II) with an optically active amino alcohol to form a first mixture of diastereomers. Preparation of (2-halophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl) compounds of formula (Ia) or its salt comprises converting benzene derivatives of formula (II) with an optically active amino alcohol to a first mixture of diastereomers. X : halo; and Y, Z : leaving groups. Independent claims are also included for the following: (1) a mixture of benzene diastereomers of formulae (IVa) and (IVb); (2) a compound (IVa); (3) a mixture of thiazo piperidine diastereomers of formulae (VIa) and (VIb); (4) compound (VIa); (5) a mixture of thiophene diastereomers of formulae (VIIIa) and (VIIIb); (6) a compound (VIIIa); and (7) preparation of 1-dimethylamino-propan-2-ol compound of formula (a) comprising reacting a diastereomeric mixtures of 1-dimethylamino-propan-2-ol of formulae (b) and (c) with L-(-)-di-O-benzoyl-L-(-)-tartaric acid (L-(-)-DBTA) and separating the L-(-)-DBTA salts of the compounds. A* : 1-30C hydrocarbon (containing 5 heteroatoms of S, O, N or halo and substituted with 5 substituents of OH, oxo, CN or nitro group) or one or more optically active units; and either R 1>, R 2>H, 1-20C hydrocarbon containing 4 heteroatoms of S, O, N or halo and substituted with 5 substituents of OH, oxo, CN or nitro groups); or C+R 1>+R 2> or R 1>+R 2>+heteroatom of A* : 5-10 membered ring (optionally saturated and optionally containing further 1-3 heteroatoms of N, O or S adjacent to the N, then a ring member is substituted with up to 5 substituents of 1-6C alkyl, 1-6C alkenyl, 1-6C alkoxy, 5-10C (hetero)aryl, 3-8C cycloalkyl, 2-8C heterocycloalkyl, halo, OH, oxo, CN or nitro (especially 1-6C alkyl, 5-10C hetero(aryl), 3-8C cycloalkyl or 2-8C heterocycloalkyl or N+R 1>+R 2> forms 3-8C saturated or unsaturated ring optionally with 1-6C alkyl or halo substituted and adjacent to N 1-2 further heteroatom of S, N or O). [Image] [Image] [Image] ACTIVITY : Anticoagulant; Thrombolytic. MECHANISM OF ACTION : Thrombocyte aggregation inhibitor.
Patent PT-1603703-E (PT)
Title: Method for connecting by welding structural sandwich plate members with channel-shaped connecting members
Inventor: KENNEDY STEPHEN J
IPC: B32B15/08
Filed: 2004-02-23
Abstract: To connect two structural sandwich plate members ( 10, 20 ), each is provided with a channel-shaped connecting member ( 14, 24 ) fitted between and projecting from the outer plates ( 11, 12, 21, 22 ). The two plate members ( 10, 20 ) are abutted and welds ( 31, 32 ) formed between the outer plates ( 11, 12, 21, 22 ).
Patent PT-1629023-E (PT)
Title: Solidification-stable blocked polyisocyanates
Inventor: HALPAAP REINHARD
IPC: C08G18/80
Filed: 2004-05-12
Abstract: Storage-stable Polyisocyanates based on aliphatic and/or cycloaliphatic diisocyanates including from 1 to 20% by weight of alkylamino groups of the formula R<1>R<2>N as a constituent of biuret groups, wherein R<1 >and R<2 >independently of one another are aliphatic or cycloaliphatic C1-C12 alkyl radicals, and where at least 95 mol % of the isocyanate groups are blocked with at least one blocking agent, and the polyisocyanates contain from 4.0 to 21.0% by weight of blocked and free NCO groups (calculated as NCO, molecular weight=42). The polyisocyanates are used to produce coating compositions, coatings, and coated substrates.
Patent PT-1605932-E (PT)
Inventor: ROBERT KRAEMER
IPC: A61P25/16
Filed: 2004-12-22
Abstract: This invention pertains to a liquid intranasal pharmaceutical formulation comprising a pharmaceutically acceptable acid addition salt of rotigotine and  alpha -cyclodextrin, preferably in the form of a buffered aqueous solution having a viscosity of 0.5 - 1.5 mm<2>/s
Patent PT-1596116-E (PT)
Title: Visual indication ring of the pressfitting of a pipe coupling
Inventor: CLINCHE PASCAL LE
IPC: F16L33/207
Filed: 2005-05-04
Abstract: The ring has several segments (19) located outside an annular portion (18) and arranged before setting the segments in a preset position. The segments are set in the preset position with respect to the annular portion by a support unit constituted of a bridge (20), and displaced to another position with respect to the annular portion by another support unit constituted of a leg (22). An independent claim is also included for a connection including an indication ring.
Patent PT-1796520-E (PT)
Title: Rod mixer comprising a plate support
Inventor: OGRIZEK DARKO
IPC: A47J43/07
Filed: 2005-08-09
Abstract: A rod mixer comprising a motor which is used to drive a processing worktool, and which is in contact with an electric circuit board which comprises at least one electric component which is used to control the motor. Said component can be modified by an associated, hand-operated actuator. The circuit board is introduced into a holder which comprises at least one bearing point, wherein the actuator is guided. The aim of the invention is to simplify mounting of the rod mixer such that the at least one actuator is premounted on the holder.
Patent PT-1932577-E (PT)
Title: Cleaning device comprising a cleaning head and method for cleaning bag-type tube filters
IPC: B01D46/04
Filed: 2006-11-15
Abstract: The cleaning device (1) has a cleaning head (5) with at least one nozzle (11) rotating round a longitudinal axis (L). The cleaning head has a jacket (15) with a smooth external surface, in which a series of through holes (17) is formed, distributed round the circumference of the jacket and arranged relative to the nozzle so that a jet from the nozzle can pass through one of the holes, at least temporarily.
Patent PT-2147044-E (PT)
Title: Low emissivity film
Inventor: MARSHALL COLIN
IPC: C08J7/048
Filed: 2008-05-21
Abstract: The present invention concerns a functional film material comprising a substrate layer and a coating layer, the coating layer comprising a block copolymeric binder and a particulate metal pigment therein, the ratio of pigment to binder in the coating layer being selected with reference to the coat weight to provide the functional film material with an emissivity of less than 0.5, and the substrate and coating layer being selected to provide the film with a VWTR (ambient) in excess 400 gm−2d−1 bar−1.
Patent PT-694071-E (PT)
Inventor: COTTEN MATTHEW
IPC: C12N15/87
Filed: 1994-04-06
Abstract: PCT No. PCT/EP94/01065 Sec. 371 Date Sep. 29, 1995 Sec. 102(e) Date Sep. 29, 1995 PCT Filed Apr. 6, 1994 PCT Pub. No. WO94/24299 PCT Pub. Date Oct. 27, 1994Viruses or cells are targeted for selective internalization into a target in vive. A molecule Specific for a receptor on the surface of the target cell is introduced onto the surface of the virus or cell. The modified virus or cell binds the receptor in vive and is internalized by the target cell. The method provides vectors for selective delivery of nucleic acids to specific cell types in vivo and a means to alter the tropism of an infectious agent.
Patent PT-785837-E (PT)
Inventor: KANG DAVID
IPC: B23K26/12
Filed: 1994-08-31
Abstract: A process and apparatus is provided for laser welding a nickel and/or cobalt based superalloy article comprising: preheating the entire weld area and adjacent region to a ductile temperature with an induction heat coil and maintaining such temperature during welding and solidification of the weld; and welding the preheated article utilizing a laser with a powder alloy feed with a control means controlling the laser, power feed and motion system on which the article is fixtured, wherein the control means includes a vision system which digitizes the weld area providing a path for the laser welding to follow.
Patent PT-798999-E (PT)
Inventor: CONWAY JOHN KELSHAW
IPC: A61F6/18
Filed: 1995-12-05
Abstract: PCT No. PCT/FI95/00666 Sec. 371 Date Jun. 2, 1997 Sec. 102(e) Date Jun. 2, 1997 PCT Filed Dec. 5, 1995 PCT Pub. No. WO96/18365 PCT Pub. Date Jun. 20, 1996An inserter for the positioning of an intrauterine device in the uterus, which inserter includes a plunger, a handle attached to the plunger, a string for the removal of the IUD, a locking device to lock the string in such a way that the IUD remains immobile in relation to the plunger, and a protective tube around the plunger. The protective tube is arranged in relation to the plunger in such a way that it can be pushed, at the forward end that goes into the uterus, past the plunger at distance (L) , which corresponds substantially to the length of the IUD assembled for insertion. The stop members ensure that the front edge of the protective tube is stopped in a configuration in which the hemispherical tips of the wings of the transverse member of a T-shaped IUD remain partly uncovered by the protective tube, but the wings nevertheless remain pressed against each other.
Patent PT-873050-E (PT)
Inventor: LIPPIELLO PATRICK MICHAEL
IPC: A61K31/44
Filed: 1995-12-27
Abstract: Patients suffering from or susceptible to an idiopathic chronic inflammatory bowel disease (e.g., ulcerative colitis) are treated with pharmaceutical compositions. Those patients are treated by administration of an effective amount of aryl substituted aliphatic compound, an aryl substituted olefinic amine compound or an aryl substituted acetylenic compound. Exemplary compounds are (E)-4-(5-pyrimidinyl)-3-butene-1-amine, (E)-4-[3-(5-methoxypyridin)yl]-3-butene-1-amine, (E)-N-methyl-4-(5-pyrimidinyl)-3-butene-1-amine, (E)-N-methyl-4-[3-(5-methoxypyridin)yl]-3-butene-1-amine, (E)-metanicotine, (Z)-metanicotine, N-methyl-(3-pyridinyl)-butane-1-amine, N-methyl-4-(3-pyridinyl)-3-butyne-1-amine and (E)-N-methyl-4 -[3-(6-methylpyrindin)yl]-3-butone-1-amine.
Patent PT-911327-E (PT)
Inventor: AMANO HIROTAKA
IPC: C07D205/04
Filed: 1996-09-20
Abstract: Pyridine carboxylic acid derivs. of formula (I) and their salts are new: R1 = H or carboxy protecting gp; R2 = OH, lower alkoxy or opt. substd. amino; R3 = H or halo; R4 = H or halo; R5 = halo or opt. substd. cyclic amino; R6 = H, halo, NO2 or opt. protected amino; X, Y, Z = N, CH or CR7; R7 = lower alkyl, halo or CN; provided that \- 1 of X-Z = N; W = N or CR8; R8 = H, halo or lower alkyl.
Patent PT-855888-E (PT)
Inventor: CAPRIO LOUIS JR
IPC: A61F13/00
Filed: 1996-10-03
Abstract: Elastic athletic or orthopedic supports for body parts such as the knee, thigh or ankle have a generally tubular sleeve made of an elastic "multi-directional" resilient stretch fabric that surrounds the body part. A patch having at least one lamination of neoprene or the like is attached within the sleeve. The patch is sized, shaped and positioned on the support element to provide a therapeutic warming to only a portion of the body part. Preferably the patch includes the second lamination of an absorbent fabric liner that is coextensive with, and secured to, the neoprene layer. The neoprene layer has a plurality of holes that extend through it to remove moisture. The liner can have like aligned holes. The liner and the patch are sewn, edge-sewn, adhered, heat-laminated, or otherwise attached to one another and to the sleeve. For a knee or elbow, the patch is generally diamond shape with its wide ends truncated and the elastic sleeve may have an opening at the rear of the knee or the inside of the elbow. For a wrist, ankle or thigh, the patch is generally a strip that wraps or extends over the injured region, with openings in the wrist and ankle sleeves for the thumb and heel, respectively. For an ankle, the strip curves downwardly at its ends to cover the ankle bone directly.
Patent PT-912805-E (PT)
Inventor: ISLEY REGGALD EMORY
IPC: E02F9/22
Filed: 1997-04-09
Abstract: A Snubber is used to damp the swing of the door on an excavator bucket to prevent the door form being damaged by repeatedly slamming shut. The snubber has housing which mounts to an excavator bucket and a shaft pivotally mounted in the housing and connected to an excavator door. The shaft turns when the excavator door opens. The housing has a cylindrical cavity around the shaft. The cavity is divided into two volumes by a dam and a wiper arm on the shaft. The wiper arm forces hydraulic fluid to flow through an orifice between the volumes as the shaft turns. The wiper arm has end seals which seal against end walls of the cavity. The end seals are forced outwardly by hydraulic pressure when the door is closing. A one-way valve allows hydraulic fluid to bypass the orifice while the door is opening. The snubber requires less maintenance than previous friction snubbers.
Patent PT-946538-E (PT)
Inventor: PEDERSEN HENRIK
IPC: A61P25/20
Filed: 1997-12-19
Abstract: The present invention relates to substituted indane or dihydroindole compounds of Formula (I), wherein A and B are independently O or S; D is an optionally substituted methylene group; X is N or optionally substituted C; and W is a spacer group. The compounds are either selective dopamine D4 ligands or they have combined effects at dopamine D4 and serotonergic receptors and/or the serotonergic transporter. These compounds are therefore useful in the treatment of certain psychiatric and neurologic disorders, including psychosis, depression and anxiety.
Patent PT-896191-E (PT)
Inventor: MOSES JOHANN
IPC: F23D14/62
Filed: 1998-07-09
Abstract: The fuel feed assembly (10), to deliver mixed gas and air to a burner, passes the fuel gas (12) through openings (23) into an inflow chamber (18) for the air (11). The air is diverted into a spiral path (20) within the inflow chamber. The gas feed openings (23) are arranged round the rotating axis (22) of the spiral flow path (20).
Patent PT-892129-E (PT)
Inventor: COWPER BRIAN
IPC: E05B9/08
Filed: 1998-07-15
Abstract: A lock comprises a body having first (14) and second (22) opposite side plates each having an orifice (16, 20) therein so as to form a passage therebetween. A cylindrical lock cylinder (2) passes through the passage and is driveably connected with a rotatable cam (8). A bolt member is mounted for movement relative to the body and is moveable by the cam (8). The lock cylinder (2) is received by first and second close-fitting sleeves (12, 24) which are secured thereto, the second sleeve (24) being removably secured, such that an inner end of each of the first and second sleeves (12, 24) abuts the first and second side plates (14, 22) respectively, so as to prevent axial movement of the lock cylinder (2). The first sleeve (12) has at least one projection (12b) on its inner end (12a) which is received in the orifice (16) of the first side plate (14) and is a close fit therein, so as to substantially prevent rotation of the first sleeve (12). The first side plate (14) has an upstanding ridge (18a) on an inner face (14a), which is located such that when the lock is in the locked position it is adjacent the cam (8) and sufficiently limits axial movement of the lock cylinder (2) that the at least one projection (12b) on the first sleeve (12) is not completely disengageable from the orifice (16) in the first side plate (14) even when the second sleeve (24) is removed, whereas when the lock is in an open position such axial movement is not limited by the ridge (18a) (Fig 2). <IMAGE>   <IMAGE>
Patent PT-989956-E (PT)
Title: Process for the preparation of polysilicate microgels
Inventor: TOKARZ MAREK
IPC: C08K3/10
Filed: 1998-06-08
Abstract: The present invention relates to polysilicate microgels, their preparation and use in paper making and water purification, the polysilicate microgels being obtainable by a process which comprises bringing into contact (i) particles of a salt AB with an aqueous silicate or polysilicate solution, (ii) an ion A with an ion B in the presence of an aqueous silicate or polysilicate solution, whereby the salt AB is precipitating in the aqueous phase, or (iii) an ion A with an ion B in the presence of an aqueous silicate or polysilicate solution, whereby the ions A and B represent ions of a precipitable salt AB having a pKS value of at least 4, measured at 20° C. in water. The invention further relates to aqueous silicate or polysilicate solutions, their preparation and use as precursors for polysilicate microgels. The aqueous silicate or polysilicate solutions contain an ion A which is calcium or magnesium, wherein the molar ratio of SiO2:A is less than 2000:1 and higher than 1:1, or an ion B which is carbonate, sulfate or phosphate, wherein the molar ratio of SiO2:B is less than 2000:1 and higher than 1:1.
Patent PT-1066071-E (PT)
Inventor: BOTICH MICHAEL J
IPC: A61M5/32
Filed: 1999-03-01
Abstract: A needle-bearing device (10) for injecting medicinal fluid from a pre-filled vial is provided. After use, the needle (50) is retracted into the body of the device to prevent inadvertent contact with the sharpened end of the needle (50). In one embodiment, the invention provides a manually actuable button that effectuates retraction of the needle (50) after use. In another embodiment, retraction is effectuated automatically after the injection is complete.
Patent SG-37792-G (SG)
Title: Anchorage rail for use in construction work
IPC: E04B1/41
Filed: 1992-04-03
Abstract: An anchor channel for use in the construction industry is provided having outwardly directed protuberances in the web of the channel with openings therethrough which are penetrated by the shaft of an anchor bolt. The bevel of the countersunk head of the anchor bolt is fitted tightly in the protuberance the inner surface of which due to material deformation is attached by a press fit to the circumferential surface of the anchor bolt. The inner surface of the opening is the shape of a truncated cone and arranged with the smaller diameter directed toward the web of the channel. The thereby formed wedge between the surface of the opening and the anchor bolt is filled by squeezing or upsetting a connecting section of the anchor bolt which has a greater cross-section or diameter and projects along the anchor bolt shaft from the countersunk head of the anchor bolt.
Patent SG-77391-G (SG)
Title: Control device for an outwardly pivoting leaf of a door or a window
IPC: E05F11/16
Filed: 1991-09-17
Abstract: A device (2) for controlling the opening and closing of an outwardly pivoting leaf (3) of a door or window, comprising an operating handle (6), such as a crank or the like, arranged on the frame (4) and actuating means of translational movement (12), these driving means (11) for the rotation of the leaf (3) interacting with second means of translational motion (46) connected to the latter and making it possible to impart to the axis of rotation of this leaf (3) a translational movement parallel to the plane of the frame (4). 
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Patent IE-790198-L (IE)
Title: Animal feed supplement
IPC: A23K20/195
Filed: 1979-02-01
Abstract: The invention relates to animal feed supplements containing antibiotic trans-BM123. Such supplements may be economically obtained by adding to a fermentation whole harvest mash containing antibiotic trans-BM123, or to a filtered fermentation broth containing antibiotic BM123, at a suitable acid pH, a complexing agent selected from synthetic tanning agents, alkali metal alkyl sulfates and dioctyl sulfosuccinate salts, whereby to precipitate out a complex of the antibiotic with said complexing agent; and recovering the precipitated complex. These complexes aid in increasing the growth rate and feed efficiency when fed to arm animals, either alone or in combination with carriers.
[EP0003644A1]
Patent FI-810026-L (FI)
Inventor: KUNG PATRICK CHUNG-SHU
IPC: G01N33/50
Filed: 1981-01-07
Abstract: Hybrid cell line for production of monoclonal antibody to an antigen found on essentially all normal human T cells and on approximately 95% of normal human thymocytes. The hybrid is formed by fusing splenocytes from immunized CAF<sub>1</sub> mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
Patent FI-810145-L (FI)
Inventor: BRICKL ROLF
IPC: C07C45/61
Filed: 1981-01-20
Abstract: Compounds of the formula   <IMAGE>   wherein R1, R2, R3 and R4, which may be identical to or different from each other, are each hydrogen, halogen, branched alkyl of 3 to 12 carbon atoms or cycloalkyl of 3 to 12 carbon atoms, provided, however, that at least one of R1 to R4 is other than hydrogen; the compounds are useful as dermatologics for the treatment of psoriasis, dandruff, ichthyosis and hyperkeratotic skin conditions.
Patent FI-832350-L (FI)
Inventor: BECKENSTROEM BO
IPC: A61F5/44
Filed: 1983-06-28
Abstract: A protector against incontinence comprises an oblong absorbent body which is fixed to a bottom liquid-tight layer extending outside the absorbent body. The lateral edge portions of the layer are folded in over the absorbent body and form side flaps, the distance between the edges thereof being less than the width of the absorbent body at its mid section. The side flaps are fixed at their ends to the bottom layer. An elastic line, arranged at the edge of each side flap, tends to contract itself and thereby the edges of the side flaps. When the protector is put on, the edges of the side flaps come into elastic sealing contact in the thigh creases of the crotch.
Patent FI-850178-L (FI)
Inventor: GLAWION RUDOLF
IPC: B66B7/02
Filed: 1985-01-16
Abstract: 1. Fastening device for guide rails of lifts, in which the guide rails (3) are held by means of rail clamps (4), which are fastened by means of a plate-shaped foot part to fastening brackets (2) arranged at the shaft wall (1) of the lift and display a limb (7), which is at an angle relative to the foot part and has a recess (8) encompassing the rail flange (6) at both sides, characterised thereby, that the limb (7) is perpendicular to the rail flange (6), that the clear width of the recess (8) is greater than the width of the rail flange (6) and that wedge-shaped undercuts (9), the narrow sides (10) of which are smaller than the thickness of the rail flange (6), are provided at the sides of the recess (8), wherein the limb (7) in the assembled state assumes an oblique position turned out of the horizontal and the oblique portions (11) of the wedge-shaped undercuts (9) touch the upper edges (12) of the rail flange (6).
Patent FI-852003-L (FI)
Inventor: ANGERBAUER ROLF
IPC: A23K20/195
Filed: 1985-05-20
Abstract: Novel  beta -lactam antibiotics of the formula   <IMAGE>   in which R1, R2 and R3, which may be identical or different, denote a substituted or unsubstituted alkyl radical or a monocyclic or bicyclic, optionally substituted, carbocyclic or heterocyclic ring, or R1 represents an optionally substituted alkyl radical or a monocyclic or bicyclic, substituted or unsubstituted, carbocyclic or heterocyclic ring, and R2 and R3, together with the N(+) atom, form an optionally substituted monocyclic or polycyclic ring which can be saturated or unsaturated and can contain oxygen, sulphur and nitrogen as other hetero atoms, or R1, R2 and R3, together with the N(+) atom, form a bridged, optionally substituted polycyclic ring which can be saturated or unsaturated and can contain oxygen, sulphur and nitrogen as other hetero atoms, and R4 represents hydrogen or optionally substituted alkyl, aryl or heterocyclyl or hydroxycarbonyl, lower alkoxycarbonyl, halogen, pseudohalogen or a group of the formula <IMAGE>   in which n denotes 0, 1 or 2, and B represents a direct bond, oxygen or a group   <IMAGE>  and A and W, independently of one another, represent hydrogen or optionally substituted alkyl, aryl or heterocyclyl, or together form an optionally substituted carbocyclic or heterocyclic ring.