Patent SG-11201900640U-A (SG)
Title: Process for producing contact lenses with durable lubricious coatings thereon
Inventor: QIU YONGXING
IPC: G02B1/04
Filed: 2017-09-14
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 29 March 2018 (29.03.2018) WIP0 I PCT ill~~~~~~~~ 011101010VIIIOH olo olum loomin mom oimIE (10) International Publication Number WO 2018/055491 Al (51) International Patent Classification: G02B 1/04 (2006.01) B29D 11/00 (2006.01) (21) International Application Number: PCT/IB2017/055577 (22) International Filing Date: 14 September 2017 (14.09.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/396,847 20 September 2016 (20.09.2016) US (71) Applicant: NOVARTIS AG [CH/CH]; Lichtstrasse 35, 4056 Basel (CH). (72) Inventors: QIU, Yongxing; c/o Alcon Research, Ltd., 11460 Johns Creek Parkway, Johns Creek, Georgia 30097 (US). PRUITT, John Dallas; c/o Alcon Research, Ltd., 11460 Johns Creek Parkway, Johns Creek, Georgia 30097 (US). TALLAU, Kelly Kayi; c/o Alcon Research, Ltd., 11460 Johns Creek Parkway, Johns Creek, Georgia 30097 (US). DRIVER-SCOTT, Angela; c/o Alcon Research, Ltd., 11460 Johns Creek Parkway, Johns Creek, Georgia 30097 (US). CHIANG, Chung-Yuan; c/o Alcon Research, Ltd., 11460 Johns Creek Parkway, Johns Creek, Georgia 30097 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(ii)) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (54) Title: PROCESS FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON (57) : The invention is related to a method for producing soft contact lenses comprises a silicone hydrogel lens body and a composite coating thereon. The composite coating comprises: a plasma base coating which is chemically-attached directly onto the surface of the silicone hydrogel contact lens and functions as a fail-proof measure for ensuring the hydrophobic silicone hydrogel lens material to be shielded from any exposure to ocular environments even after at least 30 days of daily uses including daily waring and daily cleaning/disinfecting; and a relatively-durable lubricious hydrogel top coating for ensuring wearing comfort. A method of the invention comprises forming a plasma-reactive hydrophilic polymer hybrid base coating having reactive functional groups on a silicone hydrogel contact lens and heating the silicone hydrogel contact lens with the hybrid base coating in an aqueous solution of a water-soluble and thermally crosslinkable hydrophilic polymeric material to form a stable lubricious hydrogel coating thereon. This method has a minimized adverse impact on the mechanical properties of silicone hydrogel lens body.