baber/WOPTO huggingface dataset:
Patent DE-69424177-T2 (DE)
Inventor: BRYNDZA E
IPC: B01J37/34
Filed: 1994-10-06
Granted: 2000-11-09
Abstract: An improved process for the synthesis of zerovalent nickel catalyst useful for the hydrocyanation of olefins, wherein catalyst formation is improved by applying sonication during formation of catalyst. The sonication may be applied to the catalyst reactant mixture containing elemental nickel and a ligand; or alternatively, the sonication may be applied to the elemental nickel prior to the addition of ligand to the reaction mixture.
Patent DE-69504634-T2 (DE)
Inventor: KIM SUN HYUK
IPC: C07K7/08
Filed: 1995-03-13
Granted: 1999-03-25
Abstract: The invention features linear therapeutic peptides of the following formula: <CHEM> in which A<1> is a D- alpha -aromatic amino acid or a D- alpha -tethered amino acid; A<2> is Gln, His, 1-methyl-His, or 3-methyl-His; A<3> is the D- or L-isomer selected from Nal, Trp, Phe, and p-X-Phe, where X is F, Cl, Br, NO2, OH or CH3; A<4> is Ala, Val, Leu, Ile, Nle, or  alpha -aminobutyric acid; A<5> is Val, Ala, Leu, Ile, Nle, Thr, or  alpha -aminobutyric acid; A<6> is  beta -Ala; A<7> is His, 1-methyl-His, 3-methyl-His, Lys, or  epsilon -alkyl-Lys; A<8> is Leu, Ile, Val, Nle,  alpha -aminobutyric acid, Trp, Pro, Nal, Chx-Ala, Phe, or p-X-Phe, where X is F, Cl, Br, NO2, OH or CH3; A<9> is Met, Met-oxide, Leu, Ile, Nle,  alpha -aminobutyric acid, or Cys; each R1 and R2, independently, is H, C1-12 alkyl, C7-10 phenylalkyl, or COE1, where E1 is C1-20 alkyl, C3-20 alkenyl, C3-20 alkynyl, phenyl, 3,4-dihydroxyphenylalkyl, naphthyl, or C7-10 phenylalkyl; provided that when either R1 or R2 is COE1, the other must be H; and R3 is OH, NH2, C1-12 alkoxy, C7-10 phenylalkoxy, C11-20 naphthylalkoxy, C1-12 alkylamino, C7-10 phenylalkylamino, C11-20 naphthylalkylamino; or a pharmaceutically acceptable salt of such peptides. <IMAGE>
Patent DE-69507893-T2 (DE)
Inventor: NATHAN GUY
IPC: G10K15/04
Filed: 1995-10-12
Granted: 2000-06-29
Abstract: The system includes a microprocessor associated with a display via a digital interface. Through a second interface, the microprocessor is associated with the sound playback system and through a telecommunications interface is connected to a facility for loading audio or video selection information. A control system (1021-1025) is provided which can operate in one of three modes, the mode being selected from a menu. In the first mode the device plays back information stored within its own large scale memory, whilst in the second mode the device records new digitalised information in its memory, deriving this from the telecommunications link. In the third mode, analogue information from a microphone is combined with digitised information from the memory.
Patent DE-69514301-T2 (DE)
Inventor: ARMSTRONG JR
IPC: B23D61/02
Filed: 1995-09-26
Granted: 2000-10-12
Abstract: To provide a general-purpose saw blade which will saw different materials cost effectively, the saw blade includes a plurality of sets of teeth (15,16,17), each set including saw tooth having a large relief angle (set 17) and a small tooth angle which provide fast cutting speeds, and with saw tooth having a small relief (sets 15,16) angle and a large tooth angle which provide the resistance to chipping. <IMAGE>
Patent DE-69516847-T2 (DE)
Inventor: DALUGE MARY
IPC: C07D239/48
Filed: 1995-02-03
Granted: 2000-10-26
Abstract: The present invention relates to certain novel pyrimidine intermediates and their salts, processes for their preparation and processes for their conversion to 9-substituted-2-aminopurines which are useful in medical therapy.
Patent DE-69519023-T2 (DE)
Inventor: TAMADA JANET
IPC: G01N30/88
Filed: 1995-06-23
Granted: 2001-06-13
Abstract: An iontophoresis apparatus for the transdermal monitoring of a target substance comprising: first and second collection reservoirs, the first collection reservoir comprising a first ionically conductive medium (111) and the second collection reservoir comprising a second ionically conductive medium (113); a first iontophoresis electrode (162) in contact with the first conductive medium (111) and a second iontophoresis electrode (164) in contact with the second conductive medium (113); a sensor for detecting the target substance contained within at least one conductive medium (111, 113); and an iontophoretic power source (224). The conductive medium (111, 113) is either an ionically conductive hydrogel or a wicking material containing an ionically conductive medium. The invention also includes a collection reservoir for use with an iontophoresis apparatus for the transdermal monitoring of a target substance, the collection reservoir comprising an ionically conductive hydrogel having a pH in the range of from about 4.0 to about 10.0 and an enzyme reactive with the target substance. The invention also includes a method for using the transdermal monitoring apparatus. In particular, the invention is a method for continuous in vivo monitoring of the blood glucose level of a patient comprising the following steps: (a) placing a collection reservoir on a collection site on a tissue surface of the patient; (b) applying electrical energy to the collection site to move glucose or a glucose metabolite into the collection reservoir; (c) analyzing the collection reservoir for concentration of glucose or glucose metabolite; (d) correlating the concentration determined in step (c) with blood glucose level; and (e) performing steps (a)-(d) substantially continuously. <IMAGE>
Patent DE-69528846-T2 (DE)
Inventor: LEWIS ADRIAN
IPC: A23L7/165
Filed: 1995-11-29
Granted: 2003-03-27
Abstract: Processes for producing wholegrain food products are described. Wholegrains comprising 20 % to 100 % waxy grains are cooked in the presence of moisture so as to gelatinize the grains. The gelatinized grains are formed into a dough of suitable size and shape, dried to a water content from about 4 % to about 25 %, and thereafter expanded by heating. Also described are food products produced by these processes.
Patent DE-69530219-T2 (DE)
Inventor: COLLIER KIRK
IPC: F02B43/10
Filed: 1995-05-03
Granted: 2004-02-19
Abstract: A hydrogen and natural gas fuel mixture for internal combustion engines is provided for vehicle engines such as those used in standard production engines for automobiles, trains and lawn mowers. The gaseous fuel for operating a vehicle combustion engines includes approximately 21 to 50% Hydrogen and the rest natural gas constituents such as combinations of Methane, Carbon Dioxide, Nitrogen, Ethane, Propane, Iso-Butane, N-Butane, Iso Pentane, N-Pentane, and Hexanes Plus. A fuel mixture of approximately 28 to 36 percent Hydrogen and a air fuel equivalence ratio of approximately 0.625 is an extreme lean burn condition that yields hydrocarbon emission levels of less than approximately 104 ppm (0.84 hm/hp hr.). Current internal combustion engines that are in mass production can take this alternative fuel without any substantial modifications to their systems. This alternative fuel is lean burning and emits emissions that are below current legal standards. The novel fuel mixture can be used in internal combustion engines for automobiles, lawnmowers, and trains. A control system for allowing the internal combustion engines to operate at extreme lean burn conditions is also provided for use with both a carburetor and fuel injection system. For a carburetor system, a secondary demand regulator system can kick in when a throttle is wide open and will allow additional fuel to pass through the system to meet instantaneous power demands such that occur when full throttle depression is insufficient for severe grade climbing, expressway merging, passing and the like. The fuel injection system can also be programed with a control algorithm that will select air fuel ratios. The computer control can increase fuel with respect to air when the throttle reaches a selected point of travel. The computer control can also dynamically change the hydrogen and natural gas fuel mixture ratio dynamically while the vehicle is being operated based on engine power demands and emissions.
Patent DE-69531154-T2 (DE)
Inventor: CHENARD L
IPC: C07D405/14
Filed: 1995-05-18
Granted: 2004-04-08
Abstract: PCT No. PCT/IB95/00380 Sec. 371 Date Feb. 13, 1996 Sec. 102(e) Date Feb. 13, 1996 PCT Filed May 18, 1995 PCT Pub. No. WO96/06081 PCT Pub. Date Feb. 29, 1996This invention relates to compounds of formula (I), or pharmaceutically acceptable acid addition salts thereof, wherein: (a) R2 and R5 are taken separately and R1, R2, R3 and R4 are each independently hydrogen, (C1-C6) alkyl, halo, CF3, OH or OR7 and R5 is methyl or ethyl; or (b) R2 and R5 are taken together, forming a chroman-4-ol ring, and R1, R3 and R4 are each independently hydrogen, (C1-C6) alkyl, halo, CF3, OH or OR7; and R6 is a substituted piperidinyl, pyrrolidinyl or 8-azabicyclo(3.2.1)octanyl derivative; provided that (a) when R2 and R5 are taken separately, at least one of R1, R2, R3 and R4 is not hydrogen; and (b) when R2 and R5 are taken together, at least one of R1, R3 and R4 is not hydrogen; pharmaceutical compositions thereof; and methods of treating mammals suffering from stroke, spinal cord trauma, traumatic brain injury, multiinfarct dementia, CNS degenerative diseases such as Alzheimer's disease, senile dementia of the Alzheimer's type, Huntington's disease, Parkinson's disease, epilepsy, amyotrophic lateral sclerosis, pain, AIDS dementia, psychotic conditions, drug addictions, migraine, hypoglycemia, anxiolytic conditions, urinary incontinence and an ischemic event arising from CNS surgery, open heart surgery or any procedure during which the function of the cardiovascular system is compromised with a compound of formula (I) hereinabove or a pharmaceutically acceptable salt thereof.
Patent DE-69533918-T2 (DE)
Inventor: SUZUKI SHOICHI
IPC: C12N5/10
Filed: 1995-07-06
Granted: 2005-12-01
Abstract: A DNA coding for a C4 plant phosphoenolpyruvate carboxykinase. The DNA codes for a polypeptide which has an amino acid sequence represented by SEQ ID NO: 1, 2 or 3 or an amino acid sequence obtained as the result of addition, deletion, insertion or substitution of one or more amino acid residues in the above-specified amino acid sequence, and which has a phosphoenolpyruvate carboxykinase activity.
Patent DE-69611373-T2 (DE)
Inventor: WILLNER ITAMAR
IPC: G01N5/02
Filed: 1996-07-16
Granted: 2001-08-16
Abstract: Binding between two members of a recognition pair, e.g. antigen-antibody is determined by utilizing a probe which includes a piezoelectric crystal with electrodes on two opposite faces of the crystal. The crystal carries one or more metal plates which may be the same or different than the electrodes, the metal plates having immobilized thereon a first member of a recognition pair. Binding of a second member of the recognition pair to the first member, or dissociation between the two members and release of the second member from the probe, causes a change of immobilized mass which results in a change to the probe's resonance frequency. The immobilized members may be immobilized on the surface of the metal plates by means of a linking group, having the following general formula (I): Z-R<1>-Q, wherein Z represents a sulphur-containing moiety which is capable of chemical association with, attachment to or chemisorption onto the metal, R<1 >represents a connecting group, Q is a functional group which is capable of forming a covalent bond with a moiety of said first member of the recognition pair.
Patent DE-69619523-T2 (DE)
Inventor: DANDO DAVID JOHN
IPC: G08B13/24
Filed: 1996-06-24
Granted: 2002-10-17
Abstract: PCT No. PCT/GB96/01517 Sec. 371 Date Apr. 10, 1998 Sec. 102(e) Date Apr. 10, 1998 PCT Filed Jun. 24, 1996 PCT Pub. No. WO97/01160 PCT Pub. Date Jan. 9, 1997Vertical surface protection in a security installation is achieved by detecting disturbances in a microwave beam sent from a transmitter to a receiver, both installed substantially above the ground and adjacent to the vertical surface. The transmitter and receiver have associated beam aerials of extended horizontal aperture of not less than 0.50 meters (20 inches) to mitigate the effects of surface reflection from metal scaffold, plastic sheeting or netting, wooden boarding and brick or stone facing. The aerials are preferably slotted waveguide arrays and the advantages of using circular polarization are shown. Circularly-polarized slotted waveguide arrays are disclosed having a center feed to minimize frequency-dependent beam-spreading. The sensor may be used with an intruder detector to protect buildings in scaffold by utilizing triple technology exterior detection incorporating: microwave Doppler shift; at least one and preferably two passive infra-red devices linked together through timers and lens with horizontal curtain pattern; and anti-sabotage reflected active infra-red. The system can combine the aforementioned technologies into a new device and this format overcomes the individual limitations of each of the prior art technologies when used in unison in an external scaffold environment.
Patent DE-69622969-T2 (DE)
Inventor: PONCET PHILIPPE
IPC: A61B17/28
Filed: 1996-05-20
Granted: 2003-04-24
Abstract: A surgical device for closing trocar incision sites and delivering sutures. The present invention is a needle assembly in which the needle is constructed of a spring-like material and initially housed within a sheath in a deformed condition. The needle can be easily exposed by sliding an actuator so as to release the constraining means and allow the needle to assume its undeformed condition. The needle assembly has few parts, allows a wide range for deflection of the needle, and the needle may be exposed with a relatively short stroke.
Patent DE-69624251-T2 (DE)
Inventor: REILLY M
IPC: A61M5/142
Filed: 1996-03-08
Granted: 2003-06-18
Abstract: The present invention relates to an apparatus (10) and a method for identifying a syringe (14,300) to be used with an injector (12), the apparatus comprising a syringe (42,350,400) adapter operable to carry a syringe. According to the present invention, the syringe adapter comprises a mounting device (42a,b,362a,b,410a,b) for mounting syringe adapter to the injector and an indicator (57a,b,369a,b) for identifying the syringe to be carried thereby. <IMAGE>
Patent DE-69627750-T2 (DE)
Inventor: SONNIER DAVID PAUL
IPC: H04L69/40
Filed: 1996-06-06
Granted: 2004-03-25
Abstract: A multiprocessor system includes a number of sub-processor systems, each substantially identically constructed, and each comprising a central processing unit (CPU), and at least one I/O device, interconnected by routing apparatus that also interconnects the sub-processor systems. A CPU of any one of the sub-processor systems may communicate, through the routing elements, with any I/O device of the system, or with any CPU of the system. Communications between I/O devices and CPUs is by packetized messages. Interrupts from I/O devices are communicated from the I/O devices to the CPUs (or from one CPU to another CPU) as message packets. CPUs and I/O devices may write to, or read from, memory of a CPU of the system. Memory protection is provided by an access validation method maintained by each CPU in which CPUs and/or I/O devices are provided with a validation to read/write memory of that CPU, without which memory access is denied. <IMAGE>   <IMAGE>
Patent DE-69628015-T2 (DE)
Inventor: DUNN JEFFREY
IPC: C07C237/46
Filed: 1996-06-06
Granted: 2003-12-04
Abstract: The present invention discloses a new process for producing ioversol (marketed as OPTIRAY TM ) comprising: (a) reacting 5-amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisopthalamide with chloroacetyl chloride in a polar aprotic solvent, or combinations thereof, to produce N,N'-bis[2,3-di(2-chloroacetoxy)propyl]-5-(2-chloroacetamido)-2,4,6-triiodoisophthalamide; (b) reacting the product of (a) with sodium hydroxide to produce N,N'-bis(2,3-dihydroxypropyl)-5-(2-chloroacetamido)-2,4,6-triiodoisopthalamide; (c) reacting the product of (b) in water and sodium acetate to produce N,N'-bis(2,3-dihydroxypropyl)-5-glycolamido-2,4,6-triiodoisopthalamide; and (d) reacting the product of (c) with an alkylating agent capable of producing hydroxylhylated product in the presence of a base and water to produce ioversol.
Patent DE-69628864-T2 (DE)
Inventor: AGRAWAL SUDHIR
IPC: C12N15/09
Filed: 1996-08-16
Granted: 2004-05-06
Abstract: The invention relates to modified oligonucleotides that are useful for studies of gene expression and for the antisense therapeutic approach. The invention provides inverted hybrid oligonucleotides and inverted chimeric oligonucleotides, both of which produce reduced side effects, relative to traditional phosphorothioate, hybrid or chimeric oligonucleotides.
Patent DE-69631769-T2 (DE)
Inventor: GRUBBS H
IPC: C08F32/00
Filed: 1996-08-01
Granted: 2005-03-17
Abstract: Compounds of the formula <CHEM>  wherein:     M is selected from the group consisting of Os and Ru; R<9> and R<10> are independently selected from the group consisting of hydrogen, substituted or unsubstituted alkyl and substituted or unsubstituted aryl;   X and X<1> are independently selected from any anionic ligand; and L and L<1> are independently selected from any neutral electron donor, and processes for synthesizing them.
Patent DE-69634258-T2 (DE)
Inventor: FEITELSON S
IPC: C12Q1/68
Filed: 1996-10-01
Granted: 2005-12-22
Abstract: Disclosed and claimed are novel nucleotide primers for the identification of genes encoding toxins active against nematodes and coleopterans. The primers are useful in PCR techniques to produce gene fragments which are characteristic of genes encoding these toxins. The primers are also useful as nucleotide probes to detect the toxins-encoding genes. The subject invention also concerns novel isolates, toxins, and genes useful in the control of plant pests.
Patent DE-69635374-T2 (DE)
Inventor: MCKNIGHT DOUGLAS
IPC: G06T3/40
Filed: 1996-07-18
Granted: 2006-08-03
Abstract: A device such as a display device (115, 505) or a spatial light modulator can store pixel data in a plurality of small circuits (761, 791, 801, 901, 905, 525) coupled to pixel mirrors (781, 521) and simultaneously drive these pixel mirrors (718, 521) a frame at a time. This device is particularly beneficial for implementing improved image quality techniques which can convert binary images to grey-scale images and/or separate red, green and blue images into colour images and displaying those images using the natural process of integration which occurs when a person views images at sufficiently high rates.
Patent DE-69702238-T2 (DE)
Inventor: HITERER MISHA
IPC: C25D11/04
Filed: 1997-03-11
Granted: 2001-01-25
Abstract: The invention provides a process for forming a ceramic coating on a valve metal selected from the group consisting of aluminium, zirconium, titanium, hafnium and alloys of these metals. The process includes immersing the metal as an electrode in an electrolytic bath comprising an aqueous solution of an alkali metal hydroxide, providing an opposite electrode immersed in or containing the electrolyte liquid, passing a modified shaped-wave alternate electric current from a high voltage source of at least 700 V through a surface of the metal to be coated and the opposite electrode, wherein the modified shaped-wave electric current rises from zero to its maximum height and falls to below 40% of its maximum height within less than a quarter of a full alternating cycle, thereby causing dielectric breakdown, heating, melting, and thermal compacting of a hydroxide film formed on the surface of the metal to form and weld a ceramic coating to the metal, and changing the composition of the electrolyte while the ceramic coating is being formed, the change being effected by adding an oxyacid salt of an alkali metal. The invention also provides apparatus for carrying out this method.
Patent DE-69709982-T2 (DE)
Inventor: FURLANI MICHELE
IPC: B28C9/04
Filed: 1997-05-14
Granted: 2003-03-13
Abstract: The present invention relates to a mobile concrete mixing system which substantially comprises: a feeding unit (2); a mixing unit (3); a conveyor belt; and a support structure (5) that embodies a first framework (18) supporting the conveyor belt (4), and a second framework (19) supporting the mixing unit (3). According to the present invention, the first (18) and second (19) frameworks are connected to each other by means of a hinge (22) which allows for the rotation of the first framework (18) about a substantially horizontal axis (X) in relation to the second framework (19). In this manner, a movement of the mixing unit (3) between a transporting position (23) and an operative position (24) is determined. Such a rotation about the axis (X) is obtained by keeping the mixing unit (3) in a horizontal position. In turn, by means of a mechanical actuator (27), the conveyor belt (4) is movable between a shortened condition, in the transporting position (23) of the mixing unit (3), and a lengthened condition, in the operative position (24) of said mixing unit (3). Advantageously, the configuration of the present system allows for the feeding unit (2) to be housed in a first vehicle (52), and the mixing unit (3), conveyor belt (4), support structure (5), and operating unit (40), to be housed in a second vehicle (43). <IMAGE>
Patent DE-69723689-T2 (DE)
Inventor: USALA ANTON-LEWIS
IPC: C12Q1/00
Filed: 1997-05-16
Granted: 2004-04-22
Abstract: An electrochemical biosensor for determining the level of a target chemical in a biological fluid includes an electrochemical system including a enzyme substrate which reacts with the target chemical to yield a system signal related to the concentration in the biological fluid of said target chemical. The biosensor includes a first membrane for immobilizing the enzyme substrate. The first membrane has a porosity permitting passage therethrough of the target chemical to react with the enzyme substrate and a surface exposed to the biological fluid characterized by electron donor site susceptible to facilitating attachment thereon of proteins and fibrin which impair the system signal. A second membrane is bonded to the electron donor sites of the first membrane. The second membrane is formed of a phenyl based polymer having connecting hydrogen atom donors which bond to the hydrogen atom donors bonding to the electron donor sites at least sufficiently to form an outer surface on the first membrane exposed to the biological fluid consisting of phenyl rings without significantly changing the porosity provided by the first membrane.
Patent DE-69736068-T2 (DE)
Inventor: LOLLAR S
IPC: C07K19/00
Filed: 1997-06-26
Granted: 2006-12-14
Abstract: Modified Factor VIII proteins, methods of making modified Factor VIII proteins and DNA encoding modified Factor VIII proteins are disclosed.
Patent DE-69808959-T2 (DE)
Inventor: LATTING JOHN A
IPC: C05G3/50
Filed: 1998-08-28
Granted: 2003-08-14
Abstract: The invention relates to free-flowing, powder fertilizer compositions characterized by having enhanced aqueous dissolution rates and being able to produce drift reduced aqueous agricultural spray medium. Specifically, the compositions are water-soluble, nitrogen-containing fertilizers physically blended with a guar gum drift reduction agent and a silicone defoaming agent either encapsulated or absorbed in an agricultural carrier.