Patent SG-11201901085R-A (SG)
Title: Anti-ageing pharmaceutical preparation
Inventor: WEHLING PETER
IPC: A61P39/00
Filed: 2017-05-12
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication 22 February 2018 (22.02.2018) Publication Number 2018/033227 A8 111111H1110111111010111011111010011111111111111110111010111111111011111101111 CORRECTED VERSION --, ( 10 ) International Date .......\"' WO WIP0 I PCT (51) International Patent Classification: A61K 35/14 (2015.01) A61P A61K 35/16 (2015.01) A61P A61P 29/00 (2006.01) A61P (21) International Application Number: (22) International Filing Date: 12 (25) Filing Language: (26) Publication Language: (30) Priority Data: 16001807.3 17 August 2016 PCT/EP2016/001887 14 November 2016 (14.11.2016) PCT/EP2016/001888 — 14 November 2016 (14.11.2016) UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, 17/00 (2006.01) TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, 17/18 (2006.01) EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, 39/00 (2006.01) MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, PCT/EP2017/000581 KM, ML, MR, NE, SN, TD, TG). Published: May 2017 (12.05.2017) — with international search report (Art. 2 1 (3)) English (48) Date of publication of this corrected version: English 24 January 2019 (24.01.2019) (15) Information about Correction: (17.08.2016) EP see Notice of 24 January 2019 (24.01.2019) EP EP [DE/DE]; Ernst-Schnei- Pigageallee 2a, 40597 KamerunstraBe 20, VON RENESSE 40545 Diisseldorf (DE). indicated, for every AE, AG, AL, AM, BN, BR, BW, BY, BZ, DE, DJ, DK, DM, DO, GE, GH, GM, GT, HN, KG, KH, KN, KP, KR, LY, MA, MD, ME, MG, NG, NI, NO, NZ, OM, RS, RU, RW, SA, SC, SY, TH, TJ, TM, TN, TR, ZA, ZM, ZW. indicated, for every ARIPO (BW, GH, RW, SD, SL, ST, SZ, TZ, (71) Applicant: ORTHOGEN AG _ — der-Platz 1, 40212 Diisseldorf (DE). = Inventors: WEHLING, Peter; (72) — Diisseldorf (DE). REINECKE, Julio; 50733 Koln (DE). = = (74) Agent: KONIG SZYNKA TILMANN et al.; Monchenwerther Strasse 11, = (81) Designated States (unless otherwise = kind of national protection available): AO, AT, AU, AZ, BA, BB, BG, BH, CA, CH, CL, CN, CO, CR, CU, CZ, = = DZ, EC, EE, EG, ES, FI, GB, GD, = HR, HU, ID, IL, IN, IR, IS, JP, KE, KW, KZ, LA, LC, LK, LR, LS, LU, = MK, MN, MW, MX, MY MZ, NA, PA, PE, PG, PH, PL, PT, QA, RO, = SD, SE, SG, SK, SL, SM, ST, SV, = TT, TZ, UA, UG, US, UZ, VC, VN, (84) Designated States (unless otherwise = = kind of regional protection available): = GM, KE, LR, LS, MW, MZ, NA, (54) Title: ANTI-AGEING PHARMACEUTICAL GC -.! (57) : The present invention relates t..., which is preparable by a production method N comprises cellular constituents of blood, M means, wherein (i) said production method further comprises the step of incubating said liquid in said vessel or containment means, and en optionally removing cellular constituents 0 method further comprises the steps of concentrating 3 t concentration, or the step of isolating said Il of said liquid, and the step of removing 0 ei PREPARATION a pharmaceutical preparation for use in the treatment of ageing or as an anti-ageing agent, comprising the following steps: providing a liquid collected from an organism, which liquid and a vessel or containment means and contacting said liquid with said vessel or containment of said liquid after said incubation, (ii) said liquid comprises exosomes, and said production said exosomes and optionally removing cellular constituents of said liquid after said exosomes, or (iii) said production method further comprises the step of avoiding incubation cellular constituents of said liquid contacted with said vessel or containment means. O