Patent GB-439251-A (GB)
Title: Process for the separation of electrically charged substances from very diluted trueor colloidal solutions
IPC: B01D15/00
Filed: 1934-06-26
Abstract: A process for separating electrically charged substances from very dilute true or colloidal solutions, consists in adjusting the pH value of the solution to the value for minimum solubility or dissociation of the substance to be separated and then filtering through a mass containing one or more absorbents having a charge opposed to that of the substance to be separated.  The filter mass may consist of a mixture of asbestos and kieselguhr.  The process is applicable in obtaining dyestuffs, alkaloids, hormones, ferments and the active components of drugs, and in the treatment of body fluids such as urine, blood serum, spinal fluid, and amniotic fluid.  Two or more substances may be separated from a solution by repeating the process at different pH values.  In separating porphyrine from urine the urine is filtered through a mixture of cotton fibres and asbestos, to which a negative charge has been given by treatment with alkali.  The porphyrine is recovered from the filter by extraction with glacial acetic ether, esterification with methyl alcohol hydrochloric acid and recrystallization from chloroformmethylalcohol. Cinchonine sulphate is separated from aqueous solution by filtration through a mixture of asbestos and kaolin.  The cinchonine is separated from the filtering-material by means of dilute hydrochloric acid and precipitated from the acid by addition of tannin. Strychnine is recovered from aqueous solution by filtration through a mixture of asbestos and kaolin.  The strychnine is extracted from the filter mass by means of dilute nitric acid and from the acid solution by means of ether.  The Specification as open to inspection under Sect. 91 describes also the application of the process to the recovery of adrenalin from a dilute solution of hydrochloric acid, and of metastannic acid from a very dilute solution.  This subject-matter does not appear in the Specification as accepted.ALSO:A process for separating electrically charged substances from very dilute true or colloidal solutions, consists in adjusting the pH value of the solution to the value for minimum solubility or dissociation of the substance to be separated and then filtering through a mass containing one or more absorbents having a charge opposed to that of the substance to be separated.  The filter mass may consist of a mixture of asbestos and kieselguhr.  The process is applicable in obtaining dyestuffs, alkaloids, hormones, ferments and the active components of drugs, and in the treatment of body fluids such as urine, blood serum, spinal fluid, and amniotic fluid.  Two or more substances may be separated from a solution by repeating the process at different pH values.  The Specification as open to inspection under Sect. 91 describes also the application of the process to the recovery of metastannic acid from a very dilute solution.  This subject-matter does not appear in the Specification as accepted.ALSO:A process for separating electrically charged substances from very dilute true or colloidal solutions, consists in adjusting the pH value of the solution to the value for minimum solubility or dissociation of the substance to be separated and then filtering through a mass containing one or more absorbents having a charge opposed to that of the substance to be separated.  The filter mass may consist of a mixture of asbestos and kieselguhr.  The process is applicable in obtaining dyestuffs, alkaloids, hormones, ferments and the active components of drugs, and in the treatment of body fluids such as urine, blood serum, spinal fluid, and amniotic fluid.  Two or more substances may be separated from a solution by repeating the process at different pH values.  In separating porphyrine from urine the urine is filtered through a mixture of cotton fibres and asbestos, to which a negative charge has been given by treatment with alkali.  The porphyrine is recovered from the filter by extraction with glacial acetic ether, esterification with methyl alcohol hydrochloric acid and recrystallization from chloroform-methylalcohol.  Cinchonine sulphate is separated from aqueous solution by filtration through a mixture of asbestos and kaolin.  The cinchonine is separated from the filtering-material by means of dilute hydrochloric acid and precipitated from the acid by addition of tannin.  Strychnine is recovered from aqueous solution by filtration through a mixture of asbestos and kaolin.  The strychnine is extracted from the filter mass by means of dilute nitric acid and from the acid solution by means of ether.  The Specification as open to inspection under Sect. 91 describes also the application of the process to the recovery of adrenalin from a dilute solution of hydrochloric acid.  This subject-matter does not appear in the Specification as accepted.ALSO:A process for separating electrically charged substances from very dilute true or colloidal solutions, consists in adjusting the pH value of the solution to the value for minimum solubility or dissociation of the substance to be separated and then filtering through a mass containing one or more adsorbents having a charge opposed to that of the substance to be separated. The filter mass may consist of a mixture of asbestos and kieselguhr. The process is applicable in obtaining dyestuffs, alkaloids, hormones, ferments and the active components of drugs, and in the treatment of body fluids such as urine, blood serum, spinal fluid, and amniotic fluid.  Two or more substances may be separated from a solution by repeating the process at different pH values.  In separating porphyrine from urine the urine is filtered through a mixture of cotton fibres and asbestos, to which a negative charge has been given by treatment with alkali.  The porphyrine is recovered from the filter cake by extraction with glacial acetic ether, esterification with methyl alcohol hydrochloric acid and recrystallization from chloroform-methyl-alcohol.  Cinchonine sulphate is separated from aqueous solution by filtration through a mixture of asbestos and kaolin.  The cinchonine is separated from the filtering-material by means of dilute hydrochloric acid and precipitated from the acid by addition of tannin.  Strychnine is recovered from aqueous solution by filtration through a mixture of asbestos and kaolin.  The strychnine is extracted from the filter mass by means of dilute nitric acid and from the acid solution by means of ether.  The Specification as open to inspection under Sect. 91 describes also the application of the process to the recovery of adrenalin from a dilute solution of hydrochloric acid, and of metastannic acid from a very dilute solution.  This subject-matter does not appear in the Specification as accepted.