baber/WOPTO huggingface dataset:
Patent JP-2960867-B2 (JP)
IPC: A61K9/00
Filed: 1995-08-07
Granted: 1999-10-12
Abstract: The nanoemulsion comprises: 0.1-10% (w/v) of an oil; 0.1-10% (w/v) of a non-ionic surface active agent; a maximum of 0.01% (w/v) of benzalkonium chloride; a drug or a precursor or active substance; and optionally, one or several of the following components: an isotonizing agent, a viscosity modifying agent or stabilizer, a buffer and/or an antioxidant in variable proportions. The process comprises: (a) preparing an aqueous phase containing, among others, a non-ionic surface active agent; (b) preparing an organic phase containing dissolved an oil and an active substance in an organic water miscible solvent in all proportions; (c) including the organic phase to the aqueous phase under moderate agitation; and (d) totally evaporating the organic solvent and part of the water up to the final desired volume. Important applications as an ophthalmic vehicle in preparations used to treat eye disorders and diseases.
Patent JP-4060449-B2 (JP)
IPC: A61M16/00
Filed: 1998-07-23
Granted: 2008-03-12
Abstract: NOVELTY - The gas flow sensor consists of a cylindrical permeable element (40) with axial slots along it's periphery contained within a tubular casing (16). Gas flows axially along the slots and the input/output pressure difference is detected by means of grooves (34,36) with holes (38) in the tubular casing and upstream (26) and downstream (28) pressure conduits (26,28) in the container (12).
Patent JP-3174733-B2 (JP)
IPC: G10L19/107
Filed: 1996-08-22
Granted: 2001-06-11
Abstract: PROBLEM TO BE SOLVED: To reduce the amount of calculation and the capacity of a ROM, and to obtain good synthesized sounds in a voice decoding device and a voice coding device used in efficient decoding and coding operations of voice information. SOLUTION: In the voice decoding device, the generation information on the sound source vector constituted of a small number of pulses is stored in a sound source information storage section 1. Moreover, any one of the sequence of numbers i.e., a random numeral column, the sequence of numbers obtained by a learning or the sequence of numbers obtained by knowledge, is stored in a spread vector storage section 2. Spread sound source vectors are then generated by convoluting the sound source information of the section 1 and the spread vectors of the section 2 by a convoluting section 3. The voice coding device is constituted to generate a new impulse response by convoluting the spread vectors and the impulse response from a digital filter in a convolution section.
Patent JP-2877849-B2 (JP)
IPC: C08L55/02
Filed: 1989-09-22
Granted: 1999-04-05
Abstract: The invention relates to novel thermoplastic moulding compounds made of polyamides, graft polymers which contain tert.-butyl acrylate in the shell, and, if desired, additional rubber polymers as impact modifiers.
Patent JP-4058572-B2 (JP)
IPC: A61F2/958
Filed: 1998-09-02
Granted: 2008-03-12
Abstract: This invention relates to a catheter structure for dilating and for positioning stents, comprising a catheter having an inflatable ballonn, and wherein two collars (14) are fixed around the said catheter inside the balloon ad intended to define two annular shoulders (15) one in front of the other and spaced apart in parallel. A tubular adapter (17) is arranged around the said chateter portion between the said collars, and the said balloon, when empty, is wrapped around the collars with the said tubular adapter comprised between same. <IMAGE>
Patent JP-H0631308-B2 (JP)
IPC: C07H19/167
Filed: 1985-12-13
Abstract: 1. A medicament comprising as active ingredient N6 -substituted adenosine of formula I   see diagramm : EP0186574,P11,F1   in which R1 , R2 and R3 are identical or different and represent H or the rest CH3 -CH2 -CO.
Patent JP-3160600-B2 (JP)
IPC: A61K35/28
Filed: 1999-09-30
Granted: 2001-04-25
Abstract: Human hematopoietic stem cells are provided by separation of the stem cells from dedicated cells. The stem cells may then be maintained by regeneration in an appropriate growth medium. Means are provided for assaying for the stem cells as to their capability for producing members of each of the hematopoietic lineages.
Patent JP-3076205-B2 (JP)
IPC: G06F11/10
Filed: 1994-11-29
Granted: 2000-08-14
Abstract: A novel FIFO buffer system has an error detection and correction device for effectively detecting and correcting errors therein. The system comprises M number of data storage blocks arranged in parallel for temporarily storing N-bit input digital data and generating storage state signals including full flag and empty flag signals representative of the full and the empty states thereof; an error detector, responsive to the storage state signals, for generating full error signals and empty error signals representative of the errors present among the full flag signals and empty flag signals; and an error corrector, responsive to the full error and the empty error signals, for generating full error correction signals and empty error correction signals for correcting the erroneous storage state occurred in the corresponding data storage means thereto.
Patent JP-H0616796-B2 (JP)
IPC: A61C7/28
Filed: 1990-11-15
Abstract: An orthodontic bracket, a method of manufacture and method of installing the bracket. The bracket has inner and outer tiewing edges 31, 33 which, in use, are substantially parallel to the longitudinal axis (Y-Y in Figure 3) of a tooth and top tiewing edges, bottom tiewing edges, archwire slot edges 39 and edges 41 which are substantially parallel to the occlusal plane (X-X in Figure 3) of the patient. These edges, or the entire labial face 22, of the bracket are visually enhanced, for example by a removable ink, for assistance in alignment of the bracket with respect to the tooth.
Patent JP-3810906-B2 (JP)
IPC: A61P35/00
Filed: 1997-11-12
Granted: 2006-08-16
Abstract: Etoposide phosphate is prepared by coupling dibenzyl 4'-demethyl-4-epipodophyllotoxin-4'-phosphate with 2,3-di-O-benzyl-4,6-O-ethylene- alpha , beta -D-glucopyranose in a solvent and subsequently removing the protecting groups. The tetra-benzyl protected etoposide phosphate is recrystallized from methanol or directly crystallized from acetonitrile by adding methanol to yield substantially the pure C-1''- beta  form. The benzyl protecting groups are simultaneously removed by hydrogenation to produce etoposide phosphate in high yields. In a further embodiment, etoposide phosphate is treated with a phosphatase enzyme to yield etoposide.
Patent JP-2607787-B2 (JP)
IPC: H02M3/155
Filed: 1991-09-17
Granted: 1997-05-07
Abstract: A voltage-compliant DC-DC power converter module is described. The module converts power from an input source for delivery to a load. The load is external to the power converter module and includes an external filter capacitance of value Ce for providing ripple filtering of the load voltage delivered to the load. The load is connected to the power converter module via load interconnections external to the power converter module. The load interconnections have a total parasitic load inductance of value L1. The converter module includes input terminations for connection to the input source and output terminations for connection to the load interconnections. Switching power conversion circuitry is connected to receive input power via the input terminations from the input source. The power conversion circuitry includes one or more switching devices, the switching devices delivering a pulsating voltage waveform at switching frequencies within a nominal operating range. Power delivery circuitry receives the pulsating voltage waveform from the switching power conversion circuitry and delivers power to the load via the output terminations and the load interconnections. The power delivery circuitry includes an output capacitor, of value Co, and input inductor of value Lo, and output interconnections between the output capacitor and the output terminations, the output interconnections and the output terminations having a total parasitic output inductance define a first breakpoint frequency, f1, given by the expression <MATH> which is lower than the lowest switching frequency in the nominal operating range. The output capacitance, Co, of the output capacitor included within the power delivery circuitry is both less than (a) <MATH>  and (b) <MATH>   <IMAGE>
Patent JP-H0651622-B2 (JP)
IPC: A61K31/505
Filed: 1989-12-11
Abstract: This invention relates to the use of certain derivatives of 5-hydroxy and 5-methoxy 2-amino-pyrimidines of the formula <CHEM> and the pharmaceutically-acceptable salts thereof, wherein R<1> is H or CH3; R<2> is CH3; R<3> is (C3-C15) straight chain alkyl or (C7-C20)phenylalkyl which may be substituted in the phenyl by one or two fluoro or chloro substituents; and R<4> is H or CH3 to inhibit interleukin-1 production in a mammal. This invention also relates to the use of such compounds for treating interleukin-1 mediated disorders and dysfunctions such as bone and connective tissue metabolism disorders and immune dysfunction in a mammal. The methods of this invention comprise administering an interleukin-1 production inhibiting amount of the compounds and salts of this invention to such a mammal.
Patent JP-2924033-B2 (JP)
IPC: A61K31/38
Filed: 1989-12-27
Granted: 1999-07-26
Abstract: The present invention provides a sulfur-containing heterocyclic compound of general formula (I) <CHEM> wherein ring A is a benzene ring which may be substituted; R is a hydrogen atom or a hydrocarbon group which may be substituted; B is a carboxyl group which may be esterified or amidated; X is -CH(OH)- or -CO-; k is 0 or 1; and k min  is 0, 1 or 2 or a salt thereof. Also, it provides a process for producing the compound (I) or a salt thereof and a pharmaceutical preparation for use in the treatment of osteoporosis comprising the compound (I) or salt thereof. The compounds (I) and salts thereof show excellent bone resorption inhibitory activity.
Patent JP-3476853-B2 (JP)
IPC: C12Q1/60
Filed: 1992-12-11
Granted: 2003-12-10
Abstract: The invention relates to a process for separating, by electrophoresis, Lp(a) and the various lipoproteins contained in a biological medium. The present invention is characterised in that the electrophoretic migration of the lipoproteins is performed under conditions such that the abovementioned electrophoresis gel and/or biological medium contains compounds capable of differentially modifying the electrophoretic mobility of Lp(a) relative to that of the other lipoproteins.
Patent JP-H0669952-B2 (JP)
IPC: A61K9/06
Filed: 1986-04-15
Abstract: A therapeutic compsn. for nasal admin. comprises vitamin B12 in an isotonic aq. buffer at pH 4-6 contg. sufficient thickening agent so that the viscosity is 2500-6500 cps. The compsn. may also contain 1-10 wt.% humectant and 0.2-2 wt.% surfactant. The vitamin B12 is cyanocobalamin in an amt. of 50-1000 micron and the thickening agent is methyl cellulose. Typically the concn. of the B12 is 0.05-1 wt.%.
Patent JP-2977278-B2 (JP)
IPC: G01G21/23
Filed: 1990-12-11
Granted: 1999-11-15
Abstract: This invention relates to an accurate load cell for use in mass-produced weighing devices, particularly in low-profile scales incorporating a plurality of load cells. The load cell is made from one flat piece of metal, possibly a single metal stamping, consisting of three structural elements: (1) A flat flexure beam, possibly with a narrow mid-section, on which strain sensors are bonded; (2) A flat U-shaped loaded element attached at its inner mid-section to one end of the flexure beam, with the two leading edges of the U-shaped loading element reaching beyond the mid-point of the middle beam; and (3) A flat mounting element attached at its mid-section to the other end of the flexure beam. The mounting element can also be U-shaped, with the two leading edges of the U-shaped mounting element reaching beyond the mid-point of the middle beam on the outside of the U-shaped loading element.
Patent JP-2930138-B2 (JP)
IPC: D04H1/4334
Filed: 1992-02-17
Granted: 1999-08-03
Abstract: This invention relates to a method of manufacturing an article of paper machine clothing suitable for use in the pressing section of a papermaking machine, comprising treating fibres of a polyamide material with an aqueous solution of aldehyde in the presence of a catalyst to effect partial cross-linking of the polyamide material, and attaching the fibres in the form of a fibrous batt to a fabric by needling.
Patent JP-2657503-B2 (JP)
IPC: C02F11/13
Filed: 1987-10-02
Granted: 1997-09-24
Abstract: PCT No. PCT/AU87/00338 Sec. 371 Date May 20, 1988 Sec. 102(e) Date May 20, 1988 PCT Filed Oct. 2, 1987 PCT Pub. No. WO88/02284 PCT Pub. Date Apr. 7, 1988.Method and apparatus for treating waste materials to produce aggregates wherein pellets comprised of a mixture of solids, liquid wastes and clay are dried by hot air in a dryer. The pellets are then fed to the pyrolysis zone of a rotary kiln wherein they are heated by hot gas from an oxidation zone of the kiln to drive off most of the volatile gases. Remaining volatile gases and the fixed carbon in the waste are oxidized in the oxidation zone, and the silicates in the clay are vitrified in a vitrification zone of the kiln to produce aggregates which are crushed and screened. Volatile gases given off from the pyrolysis zone are mixed with exhaust gases from the dryer to feed the burner for the vitrification zone and to supply oxygen to the oxidation zone.
Patent JP-2895621-B2 (JP)
IPC: C10G65/04
Filed: 1990-05-09
Granted: 1999-05-24
Abstract: PCT No. PCT/GB90/00718 Sec. 371 Date Dec. 11, 1991 Sec. 102(e) Date Dec. 11, 1991 PCT Filed May 9, 1990 PCT Pub. No. WO90/13617 PCT Pub. Date Nov. 15, 1990.Liquid sulphur-containing hydrocarbon feedstock is passed through two or more hydrodesulfurization zones and connected in a series each containing a packed bed of solid sulfurized catalyst. The liquid is passed from the first zone to the next until the final zone. Make up hydrogen is supplied to a hydrodesulfurization zone (i) other than the first hydrodesulfurization zone; hydrogen-containing gas is recovered from each hydrodesulfurization zone. The first hydrodesulfurization zone is supplied with hydrogen-containing gas recovered from a subsequent hydrodesulfurization zone. Hydrogen-containing gas recovered from the first hydrodesulfurization zone is purged. Liquid material recovered from the first hydrodesulfurization zone is recycled to the inlet of the hydrosulfurization zone so as to provide diluent for admixture with liquid feedstock. Any other hydrodesulfurization zone other than the first hydrodesulfurization zone and other than the hydrodesulfurization zone of step (i) is supplied with hydrogen-containing gas recovered from another hydrodesulfurization zone. The sulfur content of the hydrogen-containing gas and of the liquid hydrocarbon feedstock supplied to the first hydrodesulfurization zone is monitored and, if necessary, sulfur-containing material selected from hydrogen sulfide and active sulfur-containing materials is supplied to the first hydrodesulfurization zone so as to maintain the catalyst charge thereof in sulfided form.
Patent JP-3043353-B2 (JP)
IPC: A61K39/00
Filed: 1989-08-03
Granted: 2000-05-22
Abstract: A vaccine comprises a non-cytopathogenic strain of bovine viral diarrhoea virus, grown in a bovine derived cell line such as MDBK and killed, for example with  beta -propiolactone. The adjuvant is Quil A.
Patent JP-3952313-B2 (JP)
IPC: A61P13/12
Filed: 1995-09-06
Granted: 2007-08-01
Abstract: This invention relates to pyrazolo[3,4-g]quinoxaline compounds exhibiting protein tyrosine kinase inhibition activity of the formula:   <IMAGE>   where: ------ may be a double bond; R, R2, R3 and R4 are as described in claim 1; a pharmaceutically acceptable salt thereof. More specifically, compounds of this invention are novel as selective inhibitors of the PDGF-R protein tyrosine kinase and can be applied as potential therapeutic agents for various disease states which are characterized by uncontrolled cellular proliferation. Further, the present invention provides pharmaceutical compositions and a method for treating such disorders comprising the administration to a patient of a PDGF receptor inhibiting effective amount of a pyrazolo[3,4-g]quinoxaline compound exhibiting protein tyrosine kinase inhibition activity. Processes for the preparation of pyrazolo[3,4-g]quinoxaline compounds are also described.
Patent JP-2662095-B2 (JP)
IPC: H01L21/265
Filed: 1993-01-28
Granted: 1997-10-08
Abstract: A high current Fermi-FET includes an injector region of the same conductivity type as the Fermi-Tub region and the source and drain regions, located adjacent the source region and facing the drain region. The injector region is preferably doped at a doping level which is intermediate the relatively low doping concentration of the Fermi-Tub and the relatively high doping concentration of the source region. The injector region controls the depth of the carriers injected into the channel and maximizes injection of carriers into the channel at a predetermined depth below the gate. The injector region may also extend to the Fermi-tub depth to decrease bottom leakage current. Alternatively, a bottom leakage current control region may be used to decrease bottom leakage current. Lower pinch-off voltage and increased saturation current are obtained by providing a gate sidewall spacer which extends from adjacent the source injector region to adjacent the sidewall of the polysilicon gate electrode of the Fermi-FET. The gate sidewall spacer preferably comprises an insulator having permittivity which is greater than the permittivity of the gate insulating layer.
Patent JP-4346111-B2 (JP)
IPC: C07C217/28
Filed: 1996-09-25
Granted: 2009-10-21
Abstract: Amine containing compounds and their use in the generation of cytofectin:polynucleotide complexes for transfection of cells, formulations, counterions, and reaction conditions for maximizing the transfection include using cationic amine compounds that have general structure (I), wherein R4 and R5 are a pair of same or different lipoyl moieties selected from a group consisting of an alkyl, alkenyl, alkynyl, alkanoyl, alkenoyl, or alkynoyl groups and for R1, R2, and R3 at least two are hydroxylated, ether containing, or acyloxy containing alkyl, alkynyl, or alkynyl groups or at least one amine bonded halogen containing moiety selected from a group consisting of a halogenated alkyl, alkenyl, or alkynyl group or a mixture of at least one halogen containing moiety selected from a group consisting of a halogenated alkyl, alkenyl, or alkynyl group and at least one hydroxylated, ether containing, or acyloxy containing alkyl, alkenyl, or alkynyl group, and X<-> is an oxyanion or halide counterion.
Patent JP-3691517-B2 (JP)
IPC: G01S19/09
Filed: 1995-11-03
Granted: 2005-09-07
Abstract: The present invention combines the measured characteristics of a radio signal in a communications environment with collateral information to produce an accurate and economical way to locate a mobile transmitter station, such as a mobile telephone, in a cellular telephone network.
Patent JP-4714313-B2 (JP)
IPC: A61K31/4458
Filed: 1997-09-16
Granted: 2011-06-29
Abstract: A dosage form and a method are disclosed and claimed for administering a drug in a sustained and constantly ascending rate per unit time to provide an intended therapeutic effect while concomitantly lessening the development of unwanted effects.
Patent JP-3506178-B2 (JP)
IPC: B01L3/00
Filed: 1994-03-31
Granted: 2004-03-15
Abstract: A chromatographic assay device for use with immunoassays allows rapid and convenient assays of analytes of biological interest, and permits extractions to be carried out in situ, avoiding the use of separate extraction vessels. The device has a wide dynamic range and avoids interference from particulates or colored components. In one form, the device comprises: (1) a first opposable component comprising a sample preparation zone adapted to receive a sample to be assayed; and (2) a second opposable component comprising a chromatographic medium. The first and second opposable components can be brought into opposition so as to cause the sample preparation zone to apply the sample to be tested to the chromatographic medium. Preferably, the analyte is detected with a visually detectable label. Other variations of the device vary the arrangement of components to provide optimal chromatography for a variety of analytes, as well as to permit bidirectional chromatography; still other variations are suitable for competitive immunoassays. The devices can be incorporated in test kits, and assay methods, both sandwich and competitive, using the devices are also disclosed.
Patent JP-4472026-B2 (JP)
IPC: A61M5/178
Filed: 1997-02-20
Granted: 2010-06-02
Abstract: A syringe having a dose setting mechanism, a button which can be operated to inject a set dose, a switch operated at a time between the start and completion of injection, and an electronic presentation of parameters such as the size of a set dose and the size of the last dose administered. The syringe also has a stop watch which is reset and started responsive to operation of the switch. The electronic presentation includes an indication of the number of hours elapsed from the activation of the switch, and may also include, for a predetermined period initially following the activation of the switch, a presentation of the number of seconds elapsed. The latter presentation can provide a visual indication to the patient of the length of time, after the injection button has been actuated to inject the dose, that the needle should remain inserted in the skin.
Patent JP-3490094-B2 (JP)
IPC: C07K14/705
Filed: 1997-03-05
Granted: 2004-01-26
Abstract: Selective amplification of cells is enabled by introducing into cells a gene encoding a fusion protein comprising (a) a ligand-binding domain, (b) a domain that associates when the ligand binds to the domain of (a), and (c) a domain that imparts proliferation activity to the cells upon the association and stimulating the cells with the ligand.
Patent ES-2257173-B2 (ES)
Title: Dispositivo de tratamiento de la transmision y recepcion de señales de audio y video.
Inventor: LIN YUNG-DA
IPC: G06F13/38
Filed: 2004-09-10
Granted: 2007-11-01
Abstract: Un dispositivo de tratamiento de la transmisión y recepción de señales de audio y vídeo (AV) que incluye un descodificador de AV, un puente, y una interfaz de bus, en el que la interfaz de bus es una interfaz de bus PCMCIA, CardBus o Express Card. El descodificador de AV se usa para recibir unas señales de vídeo analógicas y una correspondiente señal de audio analógica, y proporcionar una primera señal de vídeo digital y una correspondiente primera señal de audio digital. El puente se usa para recibir la primera señal de vídeo digital y la primera señal de audio digital, y proporcionar una segunda señal de vídeo digital y una segunda señal de audio digital, que satisfacen una normativa de interfaz de bus, a un ordenador a través de una interfaz de bus que satisface la normativa de la interfaz de bus.