baber/WOPTO huggingface dataset:
Patent CA-2929754-A1 (CA)
Inventor: DEZAWA MARI
IPC: A61K35/12
Filed: 2005-04-07
Abstract: Disclosed are cells exhibiting neuronal progenitor cell characteristics, and methods of making them from marrow adherent stem cells by regulating cellular pathways in the marrow adherent stem cells that are associated with glial transdifferentiation of the marrow adherent stem cells.
Patent CA-2931859-A1 (CA)
Title: Fenestration assembly
Inventor: MASSEY VICTOR
IPC: E06B3/673
Filed: 2016-06-03
Abstract: A fenestration assembly includes a frame assembly, and a sash assembly. The frame assembly includes at least one each unitary frame member formed from a first sheet of material. The sash assembly including at least one unitary member being formed from a second single sheet of material.
Patent CA-2942263-A1 (CA)
Inventor: PSARAS DIMITRIOS
IPC: C01F17/235
Filed: 2015-03-09
Abstract: This disclosure relates to cerium (IV) oxide composition for removing biological and other contaminants from aqueous streams. It is particularly concerned with cerium (IV) oxide compositions for removing biological contaminants from groundwater and drinking water. Typically, the biological contaminants are bacteria, fungi and algae.
Patent CA-2942502-A1 (CA)
Inventor: FLICK KENNETH E
IPC: B60R16/02
Filed: 2016-09-21
Abstract: A vehicle tracker system for a vehicle including a data communications bus extending throughout the vehicle may include a multi-adaptor vehicle tracker controller including a position determining device, a wireless communications device, a controller data link interface, a download learning port, and a processor. The processor may communicate geolocation data via the wireless communications device. A data bus adaptor may adapt the tracker controller to communicate via the data communications bus and include an adaptor data link interface coupled to the controller data link interface. The data bus adaptor may be operable with a given set of proprietary remote function controller codes. The processor may be operable with different sets of proprietary remote function controller codes, and determine the given set of proprietary codes based upon the download learning port and use the given set of proprietary codes for communications with the data bus adaptor.
Patent CA-2942750-A1 (CA)
Inventor: DAR AMIT
IPC: A61N1/04
Filed: 2014-03-15
Abstract: La présente invention concerne un casque circonférentiel destiné à délivrer une stimulation électrique à la surface de la peau de la tête.
Patent CA-2943016-A1 (CA)
Title: Method for manufacturing an insulating bar
Inventor: KROHMER CHRISTOPH
IPC: B29C43/48
Filed: 2015-03-18
Abstract: In order to be able to economically produce insulating webs for composite profiles made of a thermoplastic material in the dimensions and cross-sectional configurations that are required in each case, in particular including with a ripped structure of the basic body, it is proposed for a strip-like extrudate having a substantially rectangular cross section to be formed from the plastic material in a first step and for an insulating-web arrangement to be formed from the strip-like extrudate in a subsequent step, said insulating-web arrangement having the shape of an individual insulating web or having the shape of a plurality of contiguous insulating webs arranged in parallel alongside one another, and optionally for the insulating-web arrangement to be split in the longitudinal direction thereof into mutually separate insulating webs.
Patent CA-2945370-A1 (CA)
Inventor: SMITH DARRIN E
IPC: B25H7/04
Filed: 2016-10-14
Abstract: A tool for acting on a workpiece includes a body and an adjustable element movably attached to the body. A tool member on the adjustable element is disposed on the adjustable element to act on the workpiece. The adjustable element is configured to move between a plurality of predetermined adjustment positions to locate a portion of the adjustable element a selected distance from the body. The adjustable element is resiliently biased against movement out of the predetermined adjustment positions. A micro adjustment mechanism provides for micro adjustment of a position of the adjustable element relative to the body once the adjustable element is moved to a selected predetermined adjustment position. The micro adjustment mechanism is configured for moving the adjustable element to an intermediate adjustment position located between the selected predetermined adjustment position and an immediately adjacent predetermined adjustment position for precise position adjustment of the adjustable element.
Patent CA-2945499-A1 (CA)
Inventor: NELSON SCOTT
IPC: C04B41/81
Filed: 2016-10-17
Abstract: In some examples, the disclosure describes an article and a method of making the same that includes a substrate including a ceramic or a ceramic matrix composite including silicon carbide, where the substrate defines an outer substrate surface and a plurality of grooves formed in the outer substrate surface, where each respective groove of the plurality of grooves exhibits an anchor tooth that spans an edge of the respective groove, and where the plurality of grooves define an average groove width less than about 20 micrometers, and a coating formed on the outer surface of the substrate, where the coating at least partially fills the plurality of grooves of the substrate.
Patent CA-2945509-A1 (CA)
Title: Buprenorphine dimer and its use in treatment of gastrointestinal disorders
Inventor: SINGH NIKHILESH
IPC: C07D489/02
Filed: 2015-04-27
Abstract: The present invention provides a buprenorphine dimer compound, wherein the two buprenorphine portions are linked via an ethylene spacer, wherein the spacer is bonded to the two opioid molecules via an ether bond. Pharmaceutical compositions comprising such a buprenorphine dimer drug are also disclosed, and the use of such compounds in the treatment of gastrointestinal hyperalgesia generally and in particular diarrhea-predominant irritable bowel syndrome.
Patent CA-2947586-A1 (CA)
Title: Modular pod mattress
Inventor: BAKER ROGER
IPC: A47C27/00
Filed: 2015-04-29
Abstract: The invention relates to a modular pod mattress used for sleeping. The mattress includes a structural frame having bottom rails, guide rails and a dividing rail. A plurality of modular pods are secured to the frame to form the customized mattress that relates directly to the height and weight distribution of an individual's body parts to provide the maximum quality sleep environment unique to that individual. The modular pods include a plurality of spring members, which may have varying elasticity or resistant levels. The modular pods are supported by a support platform that prevents the pods from sagging or deflecting during use of the mattress. A horizontal scale system may be utilized to determine the specific weight of a particular body part, e.g., head, shoulders, thorax, buttocks, thighs, calves and feet, of the user.
Patent CA-2948275-A1 (CA)
Inventor: ETTINGER CATHERINE
IPC: A61K39/395
Filed: 2015-04-07
Abstract: La présente invention concerne des molécules de liaison de l'IL-21, par exemple, des anticorps anti-IL-21 et des fragments de liaison à l'antigène de ceux-ci. Dans certains aspects, les anticorps anti-IL-21 et fragments de ceux-ci peuvent être des anticorps monoclonaux murins dérivés d'hybridomes et des versions humanisées de ceux-ci. Dans certains aspects, les molécules de liaison, par exemple, les anticorps anti-IL-21 et les fragments de liaison à l'antigène de ceux-ci prévus ici inhibent, suppriment ou antagonisent l'activité de l'IL -21. En outre, la présente invention concerne des compositions et des procédés pour le diagnostic et le traitement de maladies ou de troubles, par exemple, de maladies ou de troubles inflammatoires, à médiation immunitaire ou auto-immuns associés à la transduction de signal médiée par l'IL-21. Dans un mode de réalisation particulier, l'invention concerne des procédés pour traiter ou prévenir une réaction de greffe contre hôte (GVHD) à l'aide de molécules de liaison de l'IL-21, par exemple, d'anticorps anti-IL-21 et de fragments de liaison à l'antigène de ceux-ci.
Patent CA-2950632-A1 (CA)
Title: Dual 0-10v/dali streetlighting controller
Inventor: CARTMILL KEN
IPC: F21S8/08
Filed: 2016-01-25
Abstract: A streetlight controller for a streetlight is provided. An isolation section coupled to a receptacle of the streetlight for receiving a control signal that is either 0-10V dimming signal or a Digital Addressable Lighting Interface (DALI) dimming signal. A processor is connected to the isolation section, the processor detects if the control signal is a 0-10V dimming signal or DALI dimming signal and generates a control output to a light driver of the streetlight based on the detected control signal.
Patent CA-2953350-A1 (CA)
Title: Platinum compounds, compositions, and uses thereof
Inventor: MOREAU BENOIT
IPC: A61K31/282
Filed: 2015-06-23
Abstract: The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or ligand which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof.
Patent CA-2954787-A1 (CA)
Inventor: MADSEN KENNETH BANK
IPC: F25B41/04
Filed: 2015-06-23
Abstract: A method for controlling a variable capacity ejector unit (7) arranged in a refrigeration system (1) is disclosed. An ejector control signal for the ejector unit (7) is generated, based on an obtained temperature and an obtained pressure of refrigerant leaving a heat rejecting heat exchanger (3), or on the basis of a high pressure valve control signal for controlling an opening degree of a high pressure valve (6) arranged fluidly in parallel with the ejector unit (7). The ejector control signal indicates whether the capacity of the ejector unit (7) should be increased, decreased or maintained. The capacity of the ejector unit (7) is controlled in accordance with the generated ejector control signal. The power consumption of the refrigeration system (1) is reduced, while the pressure of the refrigerant leaving the heat rejecting heat exchanger (3) is maintained at an acceptable level.
Patent CA-2954927-A1 (CA)
Inventor: MICELI DAVID A
IPC: B65D50/14
Filed: 2015-07-29
Abstract: A child proof closure including an outer cap having a set of spaced apart apertures extending through a top surface of the outer cap, an inner cap dimensioned and configured to be assembled within the outer cap having a set of spaced apart receivers corresponding to the at least one set of spaced apart apertures of the outer cap, and a key having a set of spaced apart projections dimensioned and configured to be inserted through the spaced apart apertures of the outer cap to engage the spaced apart receivers of the inner cap when the spaced apart apertures of the outer cap are vertically aligned with the spaced apart receivers of the inner cap for unscrewing the assembled closure from the container by turning the key.
Patent CA-2954945-A1 (CA)
Inventor: ADLER MICHAEL
IPC: F04B43/09
Filed: 2015-07-23
Abstract: A peristaltic dosing device (1) for providing dosages of a fluid at a volume of less than one milliliter comprises: a flexible tube (13), a counter pressure element (12), a plurality of actors (11) and a drive (17). The flexible tube (13) is essentially straightly arranged along the counter pressure element (12) thereby forming a longitudinal axis. The actors (11) arranged parallel to each other along the longitudinal axis. They are moveable by the drive (17) in relation to the flexible tube (13). The flexible tube (13) is compressible between the actors (11) and the counter pressure element (12) by moving the actors (11). Each of the actors (11) is independently and linearly moveable by the drive (17) along an actuation axis essentially perpendicular to the longitudinal axis of the flexible tube (13) from a home position in which the flexible tube (13) is least compressed to an end position in which the flexible tube (13) is compressed and sealed between the respective actor and the counter pressure element (12). The peristaltic dosing device according to the invention allows for exactly and repeatably providing dosages at comparably small volumes in a sterile environment.
Patent CA-2958030-A1 (CA)
Title: Anticorps anti-hepatite c et leurs fragments de liaison a l'antigene
Inventor: PATEL ARVIND
IPC: C07K16/10
Filed: 2015-09-04
Abstract: L'invention concerne un anticorps ou un fragment de liaison à l'antigène de celui-ci capable de se lier à la poche de liaison à l'antigène de l'anticorps AP33, ledit anticorps ou fragment de liaison à l'antigène de celui-ci comprenant les régions CDR1 du domaine VL (L1), CDR2 du domaine VL (L2) et CDR3 du domaine VL (L3) qui sont respectivement constituées des séquences d'acides aminés de SEQ ID NO : 1, SEQ ID NO : 2 et SEQ ID NO : 23, ainsi que les régions CDR1 du domaine VH (H1), CDR2 du domaine VH (H2) et CDR3 du domaine VH (H3) qui sont respectivement constituées des séquences d'acides aminés de SEQ ID NO : 24, SEQ ID NO : 25 et SEQ ID NO : 26. L'invention concerne également des compositions, des méthodes, des acides nucléiques et leurs utilisations.
Patent CA-2959329-A1 (CA)
Inventor: MORALES WILFREDO JR
IPC: A61K31/496
Filed: 2015-08-24
Abstract: Processes for providing depot injections of recrystallized aripiprazole lauroxil in which particles of the aripiprazole lauroxil have a surface area of about 0.50 to about 3.3 m 2/g; and crystals of aripiprazole lauroxil produced by such processes. The present invention provides a process for making a compound of Formula (A) in crystal form wherein Ra is CH20C(O)R and wherein R1 is a substituted or unsubstituted aliphatic moiety.
Patent CA-2959595-A1 (CA)
Inventor: SINGH DIPTI
IPC: C09K8/03
Filed: 2014-09-24
Abstract: A method of treating a subterranean formation includes introducing a viscosified treatment fluid into a subterranean formation, the treatment fluid including an aqueous fluid, a gelling agent, and a crosslinker including a copolymer with an interpenetrating monomer and organic bound metal ions. A composition includes an aqueous fluid, a gelling agent; and a crosslinker including a copolymer with an interpenetrating monomer and organic bound metal ions.
Patent CA-2960782-A1 (CA)
Inventor: MCLOUGHLIN MARTIN JOHN
IPC: A61M5/32
Filed: 2015-09-21
Abstract: Provided is a housing part for an auto-injector comprising a shell form body defining inner and outer shell surfaces and comprising a relatively hard or generally incompressible material; an over-coating formed of a relatively softer or more compressible material, the over-coating covering at least part of the outer shell surface of the shell form body; and at least one window defined in the shell form body, wherein the over-coating extends into the at least one window. Also provided is a housing comprising the housing part, and an auto- injector comprising the housing.
Patent CA-2961217-A1 (CA)
Inventor: BORODIC GARY E
IPC: A61K38/48
Filed: 2015-09-14
Abstract: Described herein is a novel application involving the use of therapeutic or cosmetic formulations of botulinum toxin involving an increase and enhancement of longevity in human subjects. The inventors are physicians who have used this agent for the past 30 years for many indications and has treated a large number of patients for periods of 20-30 years, many over the age of 60 at therapy initiation for medical and aesthetic conditions. A substantial number seemed to be surviving longer than untreated patients using US census statistics. Compared to social security survival curve established over the last decade, this patient group demonstrated substantial greater longevity than the national average. Because the first remarkable patients were a group exceeding or approaching 100 years of age, the phenomenon has been termed the "centurion effect." The physiology of this effect most likely relates to the effect botulinum has on central nervous system, circadian function, sleep synchronization, mitigation of the deterioration of age related diurnal central nervous system functions, and metabolic alterations associated with the toxins effect on brainstem circadian centers.
Patent CA-2963174-A1 (CA)
Title: Procede de determination de diffusion
Inventor: LIU ZUIFANG
IPC: G01N27/327
Filed: 2015-10-26
Abstract: La présente invention concerne un procédé de détermination d'une caractéristique de diffusion d'un échantillon fluidique au moyen de réactions redox dans une cellule électrochimique qui comporte au moins deux électrodes, où la première électrode comporte au moins un médiateur redox à sa surface ou à proximité étroite de sa surface, et la deuxième électrode comporte une surface d'électrode exempte du ou des médiateur(s) redox au début d'un essai, le procédé comprenant : l'application d'un potentiel électrique à un échantillon fluidique dans la cellule électrochimique pour initier des réactions redox au niveau des deux surfaces d'électrode; la mesure d'un courant associé au potentiel appliqué en fonction du temps, et l'utilisation d'un point de mesure sur une partie transitoire du courant mesuré à ou après un point de virage et son temps associé afin de terminer la caractéristique de diffusion.
Patent CA-2975840-A1 (CA)
Inventor: SILVER REMY
IPC: F21S8/02
Filed: 2015-06-18
Abstract: A recessed track lighting fixture and an angular adjustment mechanism for the light fixture are disclosed. The fixture includes a first side member and a second side member. A linear support track is defined between the first and second side members. A displacement member is supported by the support track and is displaceable along at least a portion of the support track. A luminaire is at least partially disposed between the first and second side members, the luminaire being supported by the displacement member and displaceable therewith. The angular adjustment mechanism includes a support bracket coupled to the housing, an arcuate slot in the support bracket and a plurality of positioning apertures. A pin is coupled to the luminaire for sliding in the arcuate slot. A positioning nub is coupled to the luminaire and can be received by a positioning aperture to position the luminaire at a desired position.
Patent CA-2975956-A1 (CA)
Inventor: HUTCHINGS ADRIAN CHARLES
IPC: F01K23/04
Filed: 2016-02-11
Abstract: L'invention concerne un appareil de stockage d'énergie comprenant un premier circuit fluidique contenant un premier matériau à changement de phase, le premier circuit fluidique comprenant un premier récipient de stockage et un premier détendeur, et un second circuit fluidique contenant un second matériau à changement de phase ayant un point d'ébullition supérieur à un point d'ébullition du premier matériau à changement de phase, le second circuit fluidique comprenant un second récipient de stockage et un second détendeur. L'appareil de stockage d'énergie comprend en outre une pompe à chaleur ayant un échangeur de chaleur côté froid couplé thermiquement au premier circuit fluidique et un échangeur de chaleur côté chaud couplé thermiquement au second circuit fluidique. L'appareil peut fonctionner dans un mode de charge, un mode de stockage suivant le mode de charge, et un mode d'évacuation suivant le mode de stockage. Dans le mode de charge la pompe à chaleur est mise sous tension pour refroidir le premier matériau à changement de phase et chauffer le second matériau à changement de phase. Dans le mode de stockage le premier matériau à changement de phase est stocké dans le premier récipient de stockage et le second matériau à changement de phase est stocké sous la forme d'une vapeur sous pression dans le second récipient de stockage. Dans le mode d'évacuation le premier matériau à changement de phase vaporisé est détendu par le premier détendeur, et/ou le second matériau à changement de phase vaporisé est détendu par le second détendeur.
Patent CA-2976694-A1 (CA)
Inventor: SEEHOF CARSTEN
IPC: A63G31/16
Filed: 2016-02-22
Abstract: The present invention relates to a filter for controlling a simulator for the representation of movements of a simulated vehicle, the rotational and translational control commands required to control the simulator being calculated from a difference between the angle of rotation and the apparent vertical angle, taking into account a physiological rotation rate limitation.
Patent CA-2977376-A1 (CA)
Inventor: CADY SUSAN MANCINI
IPC: A61K47/10
Filed: 2016-02-26
Abstract: This invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a poloxamer, and a co-solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the long-acting injectable formulations of the invention to the animal in need thereof.
Patent CA-2978448-A1 (CA)
Inventor: PIELA THOMAS
IPC: H01L21/477
Filed: 2017-05-19
Abstract: An apparatus for thermal treatment of a substrate is provided. The apparatus has a heating device and a carrier provided with a support surface for the substrate.  The apparatus permits a high substrate throughput. At least part of the carrier contains a composite material that includes an amorphous matrix component and an additional component containing a semiconductor material, wherein applied to a surface of the composite material is a conductor path that is part of the heating device and that is made of an electrically conducting resistance material that generates heat when current passes through it.
Patent CA-2979800-A1 (CA)
Title: Drill bit insert and drill bit
Inventor: AKHMADI EKO WARDOYO
IPC: E21B10/46
Filed: 2016-03-17
Abstract: A drill tip that is attached to the distal end of a drill bit and that performs drilling, the drill tip having a tip main body (1) provided with a proximal-end part embedded in a bit body of the drill bit and a distal-end part that tapers toward the distal-end side and protrudes from the surface of the drill bit. The surface of at least the distal-end part of the tip main body (1) is formed from a polycrystalline cubic boron nitride sintered compact (4) containing 70 to 95 vol% of cubic boron nitride sintered by a catalyst metal that contains Al and at least one of Co, Ni, Mn, and Fe.
Patent CA-2980376-A1 (CA)
Title: Metabolomics profiling of central nervous system injury
Inventor: FRASER DOUGLAS DALE
IPC: G06F19/00
Filed: 2016-03-18
Abstract: A method of diagnosing central nervous system injuries such as acquired brain injury (ABI) and/or acquired spinal cord injury (ASI), including mild TBI (concussion or blast wave), mild ASI (contusion, stretch or partial cord transection), non-TBI brain injury and/or non-TSI spinal cord injury in a subject (animal or human). The method includes (a) obtaining a biological test sample from the subject, identifying metabolites in the subject's sample using metabolomics thereby obtaining a subject's metabolite matrix and generating a subject's profile using the patient's metabolite matrix; and (b) using multivariate statistical analysis and machine learning to compare the subject's profile with predetermined set of profiles of CNS injuries and a predetermined set of profiles of controls to determine if the subject has a CNS injury.