baber/WOPTO huggingface dataset:
Patent EP-4222279-A1 (EP)
Inventor: KENNEDY ANDREW
IPC: C12Q1/6804
Filed: 2021-09-29
Abstract: In an aspect, the present disclosure provides a method for determining a methylation status comprises: providing a biological sample of nucleic acid molecules; partitioning at least a subset of the nucleic acid molecules in the biological sample based on the methylation status of the nucleic acid molecules into a plurality of partitioned sets; digesting at least a subset of the one or more partitioned sets in the plurality of partitioned sets with at least one methylation sensitive restriction enzyme; enriching at least a subset of the nucleic acid molecules in the plurality of partitioned sets for genomic regions of interest, wherein the at least a subset of the nucleic acid molecules comprises digested nucleic acid molecules in the one or more partitioned sets; and determining methylation status at one or more genetic loci of the nucleic acid molecules in at least one of the partitioned sets.
Patent EP-4159716-A1 (EP)
Inventor: GOTO AKIYOSHI
IPC: C07C309/06
Filed: 2021-04-21
Abstract: The present invention provides an actinic ray-sensitive or radiation-sensitive resin composition with which a pattern having excellent LWR performance can be obtained, a resist film, a pattern forming method, a method for manufacturing an electronic device, a compound, and a method for producing the compound. The actinic ray-sensitive or radiation-sensitive resin composition of an embodiment of the present invention is an actinic ray-sensitive or radiation-sensitive resin composition including a resin having a repeating unit having a group having a polarity that increases through decomposition by the action of an acid, in which the actinic ray-sensitive or radiation-sensitive resin composition further includes, in addition to the resin, a compound having at least one cation represented by General Formula (1), or the resin further has, in addition to the repeating unit, a repeating unit having the cation represented by General Formula (1).
Patent EP-4240442-A1 (EP)
Title: Intraperitoneal pressure ("ipp") measurement apparatuses and systems
Inventor: BASATI SUKHRAAJ
IPC: A61M1/28
Filed: 2021-11-03
Abstract: An intraperitoneal pressure ("IPP") measurement apparatus is disclosed herein. In an example, the IPP measurement apparatus includes a transfer set or catheter that is fluidly coupled to a patient's peritoneal cavity and a pressure sensor adapted to contact the transfer set or catheter. The pressure sensor is configured to transmit output data indicative of an IPP within the patient's peritoneal cavity. The pressure sensor includes a pressure element configured to measure a pressure imparted by a fluid within the transfer set or catheter. The pressure sensor also includes a pressure amplifier having a first side that contacts a portion of the transfer set or catheter and a second side that contacts the pressure element. The first side has a greater diameter or surface area compared to the second side for amplifying the pressure signal for the IPP measurement.
Patent EP-4157428-A1 (EP)
Title: Tubing system with reassembly prevention mechanism
Inventor: CLARK DANIEL LAWRENCE
IPC: A61M39/26
Filed: 2021-05-31
Abstract: A tubing connector system is configured to connect first and second pieces of medical tubing. The tubing connector system includes a male module and a female module. The female module is retained in connection to the male module by a plurality of locking mechanisms. The plurality of locking mechanisms are configured to prevent the male module and female module from being reconnected after the male module has been separated from the female module. The tubing connector system also includes a valve assembly that includes a first valve member contained within the male module and a second valve member contained within the female module. The first and second valve members are interconnected in a gimbaled relationship.
Patent EP-4162077-A1 (EP)
Title: Lymphocyte clonality determination
Inventor: STÅHLBERG ANDERS
IPC: C12Q1/6858
Filed: 2021-06-02
Abstract: The present invention determines lymphocyte clonality by contacting a sample comprising nucleic acid molecules (1) of lymphocytes with forward and reverse primers (10, 20) and amplifying the nucleic acid molecules (1) by performing PCR pre-amplification to form barcoded PCR products (50). The barcoded PCR products (50) are amplified using adapter-specific forward and reverse primers (30, 40) in a PCR application into amplified barcoded PCR products (60), which are sequenced. The sequence reads are demultiplexed, mapped to respective TCR or BCR clonotypes and used to determine lymphocyte clonality for the sample. The forward and/or reverse primers (10, 20) are barcoded by comprising UMIs (14, 24) protected inside hairpin loops.
Patent EP-4160579-A1 (EP)
Inventor: SUN ZHOU
IPC: G09F9/33
Filed: 2021-05-06
Abstract: A display screen (10), comprising a first display area (12), which is provided with a first pixel unit array (126), and a second display area (14), which is provided with a second pixel unit array (142), wherein the pixel density of the first display area (12) is less than that of the second display area (14), the first display area (12) comprises a first sub-area (122) and a second sub-area (124), and the second sub-area (124) is connected to the first sub-area (122) and the second display area (14); and the display screen (10) further comprises a pixel driving unit array (16), which is arranged in the second sub-area (124), wherein each pixel driving unit (162) respectively drives each first pixel unit (1262), a first number of rows of pixel driving units (162) are arranged corresponding to a second number of rows of first pixel units (1262) in a row extension direction, and the first number is greater than the second number. Also disclosed is an electronic device (100).
Patent EP-4130800-A1 (EP)
Inventor: KONG QI
IPC: G01S17/06
Filed: 2021-06-16
Abstract: A method and apparatus for determining a location of a vehicle, relating to the technical field of autonomous driving. The method comprises: determining the current location point of a vehicle according to a positioning state of a GPS of the vehicle (101); obtaining laser point cloud data measured by the vehicle at the current location point and using same as first point cloud data (102); obtaining point cloud data, in a point cloud map, corresponding to a preset starting point of the vehicle, and using same as second point cloud data (103); matching the first point cloud data with the second point cloud data to determine a transformation matrix between the first point cloud data and the second point cloud data (104); and determining coordinate information of the current location point according to coordinate information of the preset starting point and the transformation matrix (105). The method and apparatus enable a vehicle to quickly and accurately obtain an accurate current location in different complex environments, without relying on a GPS device, thus avoiding the problem that a location of a vehicle cannot be determined when a GPS signal is poor or even there is no GPS signal and improving the accuracy of determining a location of a vehicle.
Patent EP-4267607-A1 (EP)
Inventor: DITTRICH WERNER
IPC: C07K16/00
Filed: 2021-12-20
Abstract: La présente invention concerne des molécules comprenant une région Fc modifiée qui ne médie pas de fonctions effectrices d'anticorps telles que la cytotoxicité à médiation cellulaire dépendante des anticorps (ADCC) mais conserve une longue demi-vie sérique due à la liaison au récepteur Fc néonatal (FcRn). A cet effet, les molécules de la présente invention ne comprennent pas les ponts disulfure de la région charnière d'anticorps mais sont liées à l'extrémité C-terminale par au moins deux liaisons covalentes. En outre, les molécules de la présente invention comprennent des domaines CH2 avec une liaison disulfure supplémentaire.
Patent EP-4182534-A1 (EP)
Inventor: GREGORIOU DANIEL J
IPC: E06B9/58
Filed: 2021-07-14
Abstract: A door assembly having a first side column and a second side column, wherein the first side column is positioned proximate a first side of the doorway and the second side column is positioned proximate a second side of the doorway, the first side column and the second side column each comprising a guide track and each guide track comprising a first portion and a second portion. The first portion of each guide track defines a first guide channel having a first depth extending from a rear portion of each guide track to a first engagement portion of each guide track, and the second portion of each guide track defines a second guide channel having a second depth extending from the rear portion of the guide track to a second engagement portion of each guide track, with the second depth being less than the first depth.
Patent EP-4204573-A1 (EP)
Inventor: GEROLD JEFFREY
IPC: C12N7/00
Filed: 2021-08-26
Abstract: The disclosure is directed in part to improved methods of making dependoparvovirus particles utilizing a nucleic acid comprising an open reading from encoding membrane-associated accessory protein (MAAP) comprising an exogenous start codon.
Patent EP-4206184-A1 (EP)
Inventor: YOSHIDA KOZO
IPC: C07C235/42
Filed: 2021-09-03
Abstract: A compound represented by formula (2) or pharmaceutically acceptable salt thereofwherein R<sup>1</sup> represents a hydrogen atom or the like; R<sup>2</sup> represents a methoxy group or the like; R<sup>3</sup> represents a hydrogen atom or the like; R<sup>4</sup> represents an optionally substituted C<sub>1-6</sub> alkyl group or the like; m represents 0, 1, or 2; n represents 0, 1, 2, or 3; L<sup>1</sup> represents -NH-C(=O)-, -C(=O)-NH-, or the like; L<sup>2</sup> represents a single bond or the like; X represents optionally substituted phenyl or the like; Y represents optionally substituted phenyl or the like; and X and Y are bonded at a carbon atom on each ring.
Patent EP-4046981-A1 (EP)
Inventor: YOUK KYUNG SEOG
IPC: C07C7/08
Filed: 2021-09-06
Abstract: Provided is a method of producing an oligomer, the method including: supplying a monomer stream and a solvent stream to a reactor to perform an oligomerization reaction to produce a reaction product; supplying a discharge stream of the reactor to a separation device, and supplying an upper discharge stream of the separation device including an unreacted monomer to the reactor and supplying a lower discharge stream of the separation device to a settling tank; settling a polymer in the settling tank and removing the polymer, and supplying the lower discharge stream of the separation device from which the polymer is removed to a high-boiling point separation column; removing a high-boiling point material from a lower discharge stream of the high-boiling point separation column and supplying an upper discharge stream of the high-boiling point separation column including an oligomer to a solvent separation column; and separating a solvent and the oligomer in the solvent separation column.
Patent EP-4216067-A1 (EP)
Inventor: MAEDA NAOYA
IPC: G06F15/02
Filed: 2021-07-26
Abstract: An information processing method includes determining a type of a selected character, among a plurality of characters included in a displayed mathematical expression, that is selection-operated by a user; identifying, based on the determined type of the selected character, an associated character, among the plurality of characters, that is associated with the character that is selection-operated; and setting, a range including the selected character and the associated character among the plurality of characters as a selection range of the character selected by the user.
Patent EP-4096167-A1 (EP)
Inventor: CHOI HO-DEUK
IPC: H01M10/42
Filed: 2021-10-05
Abstract: A battery management apparatus according to an embodiment of the present disclosure includes: a communication unit configured to output test information related to a battery; and a control unit configured to generate at least one test information related to the battery, select any one communication channel among a plurality of communication channels based on any one of a data amount of the generated test information and a state of the plurality of communication channels, generate a message packet including the test information based on a type of the selected communication channel and the data amount of the generated test information, and output the generated message packet to the selected communication channel through the communication unit.
Patent EP-4043497-A1 (EP)
Inventor: KIM MINSU
IPC: C08F20/00
Filed: 2021-08-10
Abstract: A polymerization reactor for production of a super absorbent polymer according to the present disclosure includes: a composition supply part for supplying a monomer composition solution; a central pipe connected to the composition supply part; a composition distribution part including a water storage tank located at a discharge port of the central pipe; a distribution pipe connected to the water storage tank; and an ultrasonic device installed inside the water storage tank, a conveyor belt located under the composition distribution part and on which the composition solution is dropped, and an energy supply part for supplying polymerization energy to the composition solution on the conveyor belt, wherein the ultrasonic device supplies bubbles to the composition solution flowing into the water storage tank.
Patent EP-4238629-A1 (EP)
Title: Filter and centrifugal blower
Inventor: KOBINATA HIROSHI
IPC: B01D46/52
Filed: 2021-10-26
Abstract: [Problem] To improve a strength and productivity of a filter having a filtration member in a pleated shape.[Solution] A filter (40) includes a filtration member (41) having partitioned surfaces (43) that are partitioned by mountain-fold pleats (42) and valley-fold pleats (42), and end plates (48, 49) fixed to two end portions of the filtration member (41) and configured to maintain the filtration member (41) in a pleated shape. The filtration member (41) includes a plurality of filtration portions (45a, 45b, and 45c) and intermediate portions (46a, 46b) each provided between the adjacent filtration portions. In the filtration portions (45), an angle formed by the adjacent partitioned surfaces (43, 43) is greater than 0°, and in the intermediate portions (46a, 46b), an angle formed by the adjacent partitioned surfaces (43, 43) is 0°.
Patent EP-4232027-A1 (EP)
Inventor: JORGENSEN WILLIAM L
IPC: A61K31/437
Filed: 2021-10-26
Abstract: La présente invention concerne des inhibiteurs de l'activité de la tautomérase de MIF. Dans certains modes de réalisation, les composés inhibiteurs sont utiles dans le traitement ou la prévention de maladies inflammatoires et/ou auto-immunes. Dans d'autres modes de réalisation, les composés sont utiles pour inverser, atténuer et/ou prévenir la croissance tumorale. Dans encore d'autres modes de réalisation, les composés sont utiles pour inverser, atténuer et/ou prévenir l'angiogenèse.
Patent EP-4244745-A1 (EP)
Inventor: OPUSHNYEV IGOR
IPC: G06F21/44
Filed: 2021-11-12
Abstract: A universal device identifier (UDID) service with adjusted attribute distances. In one embodiment, a server includes an electronic processor and a memory storing the UDID service. The electronic processor is configured to receive an identification request regarding a currently-observed device having a first set of device attributes, retrieve any previously-observed devices, determine whether one or more devices are found from retrieving the any of the previously-observed devices, determine all changed device attributes for each device of the one or more devices that are found relative to the first set of device attributes, generate an adjusted attribute distance corresponding to the all changed device attributes for the each device, retrieve a universal device identifier (UDID) of a closest device having a lowest adjusted attribute distance among all adjusted attribute distances that are generated, and assign the UDID of the closest device to the currently-observed device.
Patent EP-4244518-A1 (EP)
Title: Fluid handling couplings
Inventor: LANGER ELIZABETH J
IPC: F16L37/34
Filed: 2021-10-25
Abstract: Fluid couplings described herein are designed to prevent spillage of fluid when connecting and disconnecting the couplings. In some embodiments, the fluid couplings described herein include internal valve components. In some example embodiments, the internal valve components include two springs that are arranged to exert their spring forces in parallel with each other to bias a valve component to a normally closed position. Some embodiments include a single spring. In particular embodiments, components of the fluid couplings and fluid flow paths of the fluid couplings have oblong transverse cross-sectional shapes.
Patent EP-4235348-A1 (EP)
Inventor: ZHU ZHIPENG
IPC: G05F1/56
Filed: 2021-11-17
Abstract: Provided are a low dropout regulator and an electronic device. The low dropout regulator comprises a control unit electrically connected to a second capacitor, the control unit being used for controlling the connection or disconnection between a first electrode plate of the second capacitor and a second end of a power tube. Therefore, when the low dropout regulator is in a standby state, the control unit controls the disconnection between the first electrode plate of the second capacitor and the second end of the power tube, such that the second end of the power tube has a relatively small connection capacitance, so as to ensure the separation of a dominant pole point at a control end of the power tube from a secondary pole point at the second end of the power tube, and thus, the low dropout regulator has a high loop stability when same is in the standby state, thereby improving the performance of the low dropout regulator.
Patent EP-4249276-A1 (EP)
Inventor: SHIMIZU TAKAYOSHI
IPC: B41J29/13
Filed: 2021-11-10
Abstract: An embodiment of the present invention is a printer including: a body case; a platen roller configured to feed a print medium; and a printer cover being swingable relative to the body case and having an outer printer cover and an inner printer cover that are disposed to overlap each other. The inner printer cover is detachably attached to the outer printer cover, and is swingable relative to the body case, independently of the outer printer cover, when the inner printer cover is detached from the outer printer cover. The outer printer cover includes: a first holder configured to detachably hold both ends of a platen shaft of the platen roller when the inner printer cover is detached; and a second holder configured to detachably hold the platen roller when the inner printer cover is detached.
Patent EP-4255753-A1 (EP)
Title: Pinch latch assembly
Inventor: DYLEWSKI EUGENE A II
IPC: B60J7/19
Filed: 2021-12-01
Abstract: A tonneau cover for use on a cargo box of a pick-up truck is provided. The tonneau cover may include at least one panel and a latching assembly located on the at least one panel. The latching assembly selectively secures and releases the at least one panel. The latching assembly includes at least one shoe. The at least one shoe is configured for moving at least a portion of the latching assembly to release the at least one panel. The at least one shoe is movable between an extended use position and a retracted stowed position with respect to the at least one panel. And the at least one shoe is spring biased to its extended use position.
Patent EP-4257054-A1 (EP)
Title: Medical condom and automatic medical condom supply device
Inventor: KIM HEE KYUNG
IPC: A61B8/00
Filed: 2021-08-10
Abstract: Disclosed is an automatic medical condom supply device comprising: a condom supply part provided in a device body to supply, one by one, medical condom modules packaged in packaging paper; a condom withdrawal part for moving, to the outside, through an outlet formed in the device body, the medical condom module supplied from the condom supply part; a packaging paper removal part for removing the packaging paper of the medical condom module withdrawn to the outside of the device body by means of the condom withdrawal part; and a condom holding part which is provided on the outer side of the device body, and on which the medical condom discharged through the outlet is held so that a medical probe can be coupled to the medical condom from which the packaging paper has been removed.
Patent EP-4271402-A1 (EP)
Title: Composition of bl-8040
Inventor: HALBFINGER EFRAT
IPC: A61K38/10
Filed: 2021-12-29
Abstract: A composition comprising BL-8040 (SEQ ID NO: 1) is disclosed herein, which may be for use in treating a condition treatable by BL-8040. The composition further comprises at least one compound characterized by a relative retention time of from 0.86 to 0.88 and/or a relative retention time of from 0.71 to 0.73 (wherein a relative retention time of BL-8040 is 1) under conditions described herein.
Patent EP-4266200-A1 (EP)
Inventor: CHIBA DAIKI
IPC: G06F21/56
Filed: 2021-01-20
Abstract: The generation device (10) includes: an acquisition unit (15a) for acquiring information on software, an extraction unit (15b) for extracting a feature quantity of software from the information on software acquired by the acquisition unit (15a), a determination unit 15b for determining, a clustering unit (15c) for generating cluster for each software and calculating a clustering result including a center of gravity of cluster on the basis of feature quantity of software extracted by extraction unit (15b), a matching unit (15d) for matching the clustering result calculated by the clustering unit (15c) with the past clustering result when a distance between the center of gravity of the cluster included in the past clustering result calculated from the information of the malware, and a generation unit (15e) for generating a graph showing the relationship between the software and the malware on the basis of the result of matching by the matching unit (15d).
Patent EP-4287731-A1 (EP)
Inventor: LI YANHUA
IPC: H04W72/04
Filed: 2021-02-01
Abstract: Embodiments of the present disclosure relate to an information transmission method and apparatus, a communication device, and a storage medium. A base station transmits first indication information, wherein the first indication information is used for indicating an initial state of the resource configuration information of a reference signal, and the resource configuration information at least is used for indicating a transmission resource of the reference signal.
Patent EP-4258184-A1 (EP)
Inventor: FUJIMOTO JUNYA
IPC: G06N7/00
Filed: 2021-01-27
Abstract: From plural observation features of a time series acquired by observing movements of a person, plural candidate segments are decided of a target action series containing plural respective actions expressing plural movements. Each of the plural candidate segments is divided into each action segment that is a time segment of the action, a likelihood corresponding to each of the plural actions computed for each of the action segments is normalized by action segment, and as an evaluation value a representative value is computed of normalized likelihood corresponding to each of the action segments selected from out of all of the respective action segments in the candidate segments based on an order of actions in the target action series. Being the target action series is determined in cases in which the evaluation value exceeds a common threshold.