baber/WOPTO huggingface dataset:
Patent ZA-838442-B (ZA)
Title: Integral reagent dispenser
Inventor: SMITH JOHN L
IPC: G01N35/00
Filed: 1983-11-11
Abstract: An integral reagent dispenser comprises a reagent dispenser component provided with a reagent dispenser well (75) having an opening adapted to present a liquid reagent (R1) for withdrawal therethrough and means to position a lens (100) of liquid, immiscible with said reagent, between the reagent and the opening of said well. For example, the dispenser can have suitable dimensions and an inner surface (77) which combine with the wetting characteristics of the reagent to form a concave reagent meniscus (97) suitable to reliably position a lens of immiscible liquid thereon. The sens so formed is centrally located by the concave shape of the meniscus. Preferably, the reagent dispenser further includes an integrally associated source of reagent (30).
Patent ZA-841287-B (ZA)
Title: Process for the preparation of solid pharmaceutical products
Inventor: PICH CLAUS HINRICH
IPC: C07C67/00
Filed: 1984-02-22
Abstract: A process for the preparation of solid pharmaceutical products, wherein, in a first step, spherical single crystals of a pharmaceutical active compound or assistant are prepared by agitating a saturated aqueous, organic or organic-aqueous solution in high speed stirred crystallizers or draft-tube crystallizers at 50-500 revolutions per minute and seeding the solution with finely ground seed crystals of particle size less than 100  mu m, while ensuring that at the time of addition of the seed crystals and during the growth thereof the solution is at all times only minimally supersaturated, this being achieved by slow cooling at a rate of not more than 50 K/h or corresponding slow evaporation of the solution, and in a second step the resulting spherical single crystals with diameters of 0.1-3 mm, preferably 0.5-2 mm, are separated from the solution, dried at 40 DEG -200 DEG  C., compounded, where appropriate, with suitable pharmaceutical assistants or, if the single crystals serve as assistants, with suitable pharmaceutical active compounds, and then converted to solid pharmaceutical products by coating, tableting or filling into hard gelatin capsules.
Patent ZA-855124-B (ZA)
Title: Phenol-naphthyridines,process for preparing them,drugs containing them,particularly anti-ulcer drugs
Inventor: TEULON JEAN-MARIE
IPC: A61K31/435
Filed: 1985-07-08
Abstract: This invention relates to novel compounds of formula:    <IMAGE>  (I) having an anti-ulcer activity.
Patent ZA-855396-B (ZA)
Title: Process for the synthesis of 2,2,2-trifluoroethanol and 1,1,1,3,3,3-hexafluoroisopropyl alcohol
Inventor: CHEMINAL BERNARD
IPC: C07C31/40
Filed: 1985-07-17
Abstract: A process for producing 2,2,2-trifluoroethanol or 1,1,1,3,3,3-hexafluoroisopropanol which comprises hydrogenating a fluoro compound having the formula   <IMAGE>   wherein R1 is hydrogen or CF3 and R2 is hydrogen or a straight- or branched-chain alkyl group, which can also be fluoro-substituted, in the liquid phase in the presence of a palladium-on-activated-carbon catalyst, and if desired a tertiary amine co-catalyst.
Patent ZA-871515-B (ZA)
Title: Fluoride-free flux compositions for hot galvanization in aluminium-modified zinc baths
IPC: C23C2/30
Filed: 1987-03-03
Abstract: PCT No. PCT/BE87/00003 Sec. 371 Date Nov. 4, 1987 Sec. 102(e) Date Nov. 4, 1987 PCT Filed Mar. 3, 1987 PCT Pub. No. WO87/05337 PCT Pub. Date Sep. 11, 1987.The disclosed flux compositions contain by weight: from 80 to 90% of ZnCl2, from 10 to 20% of NH4Cl and, based on the weight of ZnCl2+NH4Cl, from 0.01 to 5% of a wetting agent, from 0 to 5% of a forming agent, from 0 to 5% of a soluble salt of rare earths. The flux compositions according to the invention may be used as galvanization flux in the dry process with baths containing more than 0.15% of aluminum, particularly for baths of galvanization alloy containing 5% of aluminum, 95% of zinc and Mischmetall additions.
Patent ZA-883681-B (ZA)
Title: Novel fusion protein
Inventor: SMITH DONALD BRUCE
IPC: C12N5/00
Filed: 1988-05-24
Abstract: A recombinant DNA molecule is claimed comprising a nucleotide sequence which codes on expression for a fusion protein in which a foreign protein or peptide is fused with a glutathione-S-trasferase (GST) enzyme. Pref. the enzyme is a 26kD GST of Schistosoma japonicum. The foreign protein or peptide may be fused to the enzyme through a lint cleavable by e.g. thrombin, blood coagulation factor Xa or renin. Also claimed is an expression vector having inserted a nucleotide sequence capable of being expressed as a GST enzyme followed by at least one restriction endonuclease recognition site for insertion of a nucleotide sequence capable of being expressed as a Foreign protein or peptide fused to the GST. The fusion protein is also claimed.
Patent ZA-907297-B (ZA)
Title: Conjugate vaccine for group B streptococcus.
Inventor: MICHEL JAMES L
IPC: C07K16/00
Filed: 1990-09-13
Abstract: A vaccine capable of protecting a recipient from infection caused by group B Streptococcus. The vaccine is formed by conjugating (a) a polysaccharide conjugated to (b) a protein; wherein both the polysaccharide and the protein are characteristic molecules of the group B Streptococcus.
Patent ZA-907648-B (ZA)
Title: Use of a polypeptide having the activity of human interleukine 2 for the preparation of pharmaceutical compositions intended for the treatment of leukemias
Inventor: BRANDELY MAUD
IPC: A61K38/00
Filed: 1990-09-25
Abstract: The invention relates to the use of a polypeptide having human interleukin-2 activity for preparing a pharmaceutical composition intended for the treatment of leukaemias. Polypeptide having human IL-2 activity is understood to mean natural human IL-2 or recombinant human IL-2, that is to say obtained by recombinant DNA technology. The leukaemias to which the invention relates comprise chronic myeloid or chronic lymphoid leukaemias and acute lymphoid or non-lymphoblastic leukaemias, for example myeloid leukaemias characterised in a general manner by the proliferation of blast cells.
Patent ZA-908920-B (ZA)
Title: Multiple motion centrifuge
Inventor: PRAIS A WESLEY
IPC: B04B5/02
Filed: 1990-11-07
Abstract: A centrifuge device is provided which may impart selectively controlled centrifugal force to samples (30,32) under consideration, or a shaking or agitation movement to the samples, as required. A feature of the invention is the use of two roller clutches (18,20) on the single drive shaft (14) of the device so that a selective movement may be imparted to the samples (30,32) through the same drive by utilizing a locking mechanism to provide rotation from the shaft in opposite directions. Rotation in one direction causes the imposition of centrifugal force through one clutch (20), while rotation in the opposite direction causes rotation through the second clutch (18) and the imposition of agitation. In that direction, the sample support mechanism is moved vertically, controlled by a cylinder cam (76). A further feature of the invention is selective agitation movement and selective degree of agitation through selection of a particular cam profile (70). <IMAGE>
Patent ZA-919554-B (ZA)
Title: 38-decarboxy-38-hydroxymethyl derivatives of tetcoplanin antibiotics,and a process for preparing them
Inventor: MALABARBA ADRIANO
IPC: C07K9/00
Filed: 1991-12-04
Abstract: The present invention is directed to novel 38-decarboxy-38-hydroxymethyl derivatives of teicoplanin antiobiotics and a process for preparing them which includes submitted the corresponding lower alkyl ester precursor to a reduction reaction in the presence of an alkali metal borohydride. The compounds of the invention show an improved antibacterial activity against some clinical isolates of Staphylococci somewhat resistant to teicoplanin. The teicoplanin derivatives of the present invention are represented by the following formula:   <IMAGE>   wherein: X represents hydroxymethyl; R represents hydrogen or -N[(C9-C12)aliphatic acyl]- beta -D-2-deoxy-2-aminoglucopyranosyl; R1 represents hydrogen or N-acetyl- beta -D-2-deoxy-2-aminoglucopyranosyl; R2 represents hydrogen of alpha-D-mannopyranosyl; R3 represents hydrogen or a protecting group of the amino function; and the acid addition salts thereof; with the proviso that R1 represents hydrogen only when R and R2 are simultaneously hydrogen.
Patent ZA-921366-B (ZA)
Title: Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
Inventor: OSHLACK BENJAMIN
IPC: A61K9/36
Filed: 1992-02-25
Abstract: A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active with an aqueous dispersion of ethylcellulose and then curing the coated substrate at a temperature and relative humidity elevated to a suitable level above ambient conditions until the coated dosage form attains a stabilized dissolution profile substantially unaffected by exposure to storage conditions of elevated temperature and/or elevated relative humidity. <IMAGE>
Patent ZA-927432-B (ZA)
Title: Chemical compounds.
Inventor: DALEN ARE
IPC: A61K31/7064
Filed: 1992-09-28
Abstract: Fatty acid esters (I) of nucleosides or nucleoside analogues are new, where the fatty acid is a monounsatd. 18 to 20C fatty acid esterified with the 5'-OH gp. of nucleosides or with an OH gp. on the noncyclic chain of nucleoside analogues. (I) have higher activity than the parent nucleosides or analogues and have relatively low toxicity. Pref., (I) are esters of acyclovir, Ara T, Ara A or AZT with oleic acid, elaidic acid or cis- or trans-eicosenic acid.
Patent ZA-964416-B (ZA)
Title: Carrier-bound light stabilizers and antioxidants as filler and stabilizers
Inventor: NESVADBA PETER
IPC: C09K15/08
Filed: 1996-05-30
Abstract: Cpds. of formulae (I) -(IV) fixed on a support are claimed. The use of the cpds. as fillers, and stabilisers for organic materials against oxidative, thermal or light-induced breakdown esp. as heat stabilisers for thermoplastic polymers and the organic compsns. contg. the cpds. are also claimed. R1,R2 =1-16C alkyl, 5-12C cycloalkyl, Ph or 7-9C phenylalkyl; R4,R5 = R, 1-20C alkyl, Ph or naphthyl opt. substd. with 1-4C alkyl, NH4 or Mr+/r; R6 = H, 1-18C alkyl, 5-12C cycloalkyl, 7-9C phenylalkyl, NH4 or Mr+/r; R7 = 1-18C alkyl, Ph opt. substd. wit 1-4C alkyl, or -(CH2)q-COOR6; R8 = 1-8C alkyl; R9 = H, 1-8C alkyl, O degrees (sic), OH, NO, -CH2CN, 1-18C alkoxy, 5-12C cycloalkyloxy, 3-6C alkenyl or alkynyl, 1-8C acyl, or 7-9C phenylalkyl opt. substd. on the Ph ring with 1-4C alkyl; R10 = -COX5COOR6, glycidyl or -X6COOR6; R11 = H or 1-18C alkyl; R12 = 1-18C alkyl or 2-14C alkenyl; R13 = H or 1-4C alkyl; M = metal cation with valency r; X1 = direct bond, 1-8C alkylene, 2-8C alkylene broken by O or S, -CH2CH(R8)- or gp. of formula (V); X2 = O or NH; X3 = 1-6C alkylene; X4 = O or NR11; X5 = direct bond, 1-8C alkylene, 2-6C alkenylene, =CH(R12) or gps. of formula (VI)-(VIII); X6 = 1-18C alkylene, 2-18C alkylene, 2-18C alkylene broken by O or S, or phenylene; m = 0-2; n = 1-6; p,q = 1 or 2; r = 1-3; when n = 1, then R3 = H, 1-25C alkyl, 5-12C cycloalkyl, Ph opt. substd. with 1-4C alkyl, or a monovalent residue of a hexose or hexitol, and if X2 = O, then R3 may = NH4 or Mr+/r; or, when n = 2, then R3 = 2-12C alkylene, 4-12C alkylene broken by O or S, or a divalent residue of a hexose or hexitol; or when n = 3, then R3 = -CH2-CH-CH2- or a trivalent residue of a hexose or hexitol; or when n = 4, then R3 = 4-10C alkane tetrayl or a tetravalent residue of a hexose or hexitol; or when n = 5, then R3 = a pentavalent residue of a hexose or a hexitol; or when n = 6, R3 = gp. (IX) or a hexavalent residue of a hexitol. The cpds. adhere well to the support and are not easily extracted by solvents, e.g. alcohols or hydrocarbons.
Patent ZA-968138-B (ZA)
Title: Methods and compositions for controlling biofouling using thiourea compounds
Inventor: ZOLLINGER MARK L
IPC: C09D5/14
Filed: 1996-09-27
Abstract: The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one thiourea to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one thiourea to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the bactaria. The thiourea used in the method of the invention has the following formula a compound of the formula: The present invention also relates to compositions containing thiourea compounds and useable in the above methods. The compositions comprise at least one thiourea in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
Patent ZA-995213-B (ZA)
Title: Oxime carboxylic acid derivatives.
Inventor: ANDERSON DENISE
IPC: C07C251/62
Filed: 1999-08-16
Abstract: The present invention is an oxime carboxylic acid derivative having the formula I:wherein n is 1 or 0, X is O, R2 and R3 being part of an oxime R2R3C=NOH are individually, substituted or unsubstituted, branched or unbranched alkyl-, alkenyl-, akinyl-, cycloalkyl-, cycloalkenyl-, or aromatic radical and contain less than 30 carbon atoms, and R1 is a substituted or unsubstituted, branched or unbranched alkyl-, alkenyl-, akinyl-, cycloalkyl-, cycloalkenyl-, alkoxyalkyl-, aryloxyaryl-, alkoxyaryl-, aryloxyalkyl-, or aromatic radical, or XnR1 iswhich are useful as precursors for the delivery of organoleptic compounds, especially for flavors, fragrances and masking agents, and/or antimicrobial compounds.
Patent AT-409504-B (AT)
Title: Sorting machine, to clean a fiber suspension, is in a double configuration with rotors and cylindrical sieve bodies and outlet zones for the filtered suspension and rejected matter for improved flow and lower energy consumption
Inventor: GABL HELMUTH DIPL ING DR
IPC: D21D5/02
Filed: 2001-02-15
Granted: 2002-09-25
Abstract: The sorting machine, to clean a fiber suspension, is a double machine with a rotor, and a fixed cylindrical sieve body where the fiber suspension is fed into its interior. The zone for the filtered suspension and the outlet for rejected matter are outside the sieve cylinder. The sorting assembly, to clean a fiber suspension, has a suspension feed which is aligned axially through the rotor. The section of the rotor at the drive side is at a height level which is equal to or greater than at the other rotor section. The fiber suspension feed can be at the center, from the side. The outlets for the filtered suspension are doubled. The suspension sorting machine lies horizontally
Patent GB-2383106-B (GB)
Title: Method of fastening
Inventor: CRUTCHLEY DEREK
IPC: F16B23/00
Filed: 2001-12-14
Granted: 2004-09-15
Abstract: A method and fastener for fastening one or more apertured members (48) to an apertured workpiece (52), an aperture (50) of the or each member (48) being aligned with an aperture (54) in the workpiece (52), the method comprising the steps of inserting a fastener (10) into the aligned apertures, the fastener (10) being formed of ductile material and having a head (14), a shank (12), and an axial bore (22) extending through the shank (12) and into the head (14), the shank (14) being circumferentially entire and being formed with an external screw-thread (18) the fastener (10) being inserted so that the head (14) engages a face of the one member (48), and the shank (12) extends through the member (48) or members and into the workpiece (52), and at least a part of the screw-thread (18) is within the workpiece (52), and then, while supporting the fastener (10) at the head (14), drawing into and entirely through the bore (22), in the direction from the tail portion to the head (14), a tapering, enlarged, mandrel head (32) capable of expanding the bore (22) and thereby enlarging the bore (22) evenly throughout its length and causing ductile radial expansion of the shank (12) sufficient to case the external screw-thread (18) to embed in the workpiece (52) and the shank (12) of the fastener (10) undergoing ductile axial reduction in length.
Patent GB-2390112-B (GB)
Title: Snap fastener for use with fabrics
Inventor: STUBBS MICHAEL JOHN
IPC: A44B17/00
Filed: 2002-06-26
Granted: 2005-09-07
Abstract: A snap fastener for use with fabrics comprising a flange having a cyclindical wall extending axially therefrom, the wall comprising a plurality of circumferentially extending engaging portions each engaging portion being separated from the next by a circumferentially extending non engaging portion.
Patent GB-2391231-B (GB)
Title: Modulation of cytochrome P450 reductase activity
Inventor: WOLF ROLAND
IPC: C12N15/85
Filed: 2003-07-09
Granted: 2005-12-14
Abstract: A conditional hepatic cytochrome P450 reductase specific null homozygous non-human transgenic animal having depleted or ablated cytochrome P450 reductase (CPR) expression and other phenotypic characteristics.
Patent GB-2411106-B (GB)
Title: Cartridge for the preparation of beverages
Inventor: HALLIDAY ANDREW MICHAEL
IPC: B65D85/804
Filed: 2004-02-17
Granted: 2006-11-22
Abstract: A cartridge containing one or more beverage ingredients and being formed from substantially air- and water-impermeable materials. The cartridge comprises an inlet for the introduction of an aqueous medium into the cartridge, and an outlet for a beverage produced from the one or more beverage ingredients. The cartridge comprises means for producing a jet of the beverage having an aperture in a beverage flow path linking the inlet to the outlet, and one or more microscopic projections at or in the vicinity of the aperture for contacting the beverage flow path.
Patent GB-2471710-B (GB)
Title: Energy converting system
Inventor: LYNN KUO-YUAN
IPC: F24S23/30
Filed: 2009-07-10
Granted: 2013-12-04
Abstract: An energy converting system for converting solar energy and wind energy into kinetic energy comprises a fixed shaft unit 2 including an upright fixed shaft 21, and a windmill device 3 with a first windmill unit 31 which includes two first blades (315, fig.4). A light-focusing device 4 is co-rotatable with the first windmill unit and includes a light-focusing wall 42 defining a heating compartment 43. The light-focusing wall has a structure to focus solar energy as rays of sunlight into the heating compartment to thereby heat and pressurise air within the compartment. Rotation of the first blades of the first windmill unit results in an upward flow of air into the heating compartment to further pressurise the air within the compartment. This enables the air to be jetted out of the heating compartment in such a manner as to rotate the light-focusing device and, thus, the windmill device about the fixed shaft. The light focusing wall may be composed of at least one lens and, preferably, is composed of a plurality of interconnected lenses.
Patent GB-2062424-B (GB)
Title: Bradcast teletext system
IPC: H04N7/08
Filed: 1979-10-31
Granted: 1983-04-07
Abstract: Each broadcast page contains a row such as row 29 which is outside the set of displayed rows. In addition to the standard initial bytes CR (clock run in), FC (framing code) and MRAG (magazine number of 3 bits and row number of 5 bits), there are 4 bytes allocated to a 16-bit cyclic rundancy check code CRC for the page and 6 groups, of 6 bytes each, NEXT 0 to NEXT 5. Bytes are Hamming coded and thus contain only 4 message bits. Each 6-byte group is a pointer to another page address made up of page tens and page units (4 bits each), hour code tens and units (2 bits plus 4 bits) and minute code tens and units (3 bits plus 4 bits). The three spare bits from the tens bytes for hours and minutes contain a number which is normally 0 but, if not 0, is added modulo-8 in the decoder to the current magazine number in MRAG to derive the magazine number for the 'next' page. A decoder equipped with a multipage store can respond to the pointers to acquire a sequence of pages automatically, all available immediately to the viewer. A specific line, not related to any particular page, say magazine 8 row 30, can be transmitted say once a second and includes a 6-byte group addressing a title page. Whenever a receiver is switched on or to a channel carrying teletext, the decoder automatically responds to this line to acquire the addressed title page.
Patent GB-2066143-B (GB)
Title: Method of manufacturing a slide fastener
IPC: B29C45/14
Filed: 1980-12-08
Granted: 1984-03-14
Abstract: A series of equally spaced holes 12 are formed in a slide fastener stringer tape 10 including synthetic fiber by thrusting and melting away tape portions spaced along a marginal edge of the tape 10 on and between an ultrasonically vibrating horn 23 and an endless series of teeth 29 successively pressable against the horn 23. The stringer tape 10 is then moved away from the horn 23 so as to be cooled for thereby setting the holes 12. Thereafter, a series of coupling elements 13 are injection-molded at the same time on the stringer tape 10 over the holes 12, respectively. <IMAGE>
Patent GB-2077963-B (GB)
Title: Electronic timepiece
IPC: G04G3/02
Filed: 1981-04-29
Granted: 1983-11-16
Abstract: An electronic timepiece includes two oscillator circuits (a,b) each of which has a piezoelectric oscillator (1, 2), the piezoelectric oscillators having materially different oscillation frequencies. Each oscillator circuit is connected to a respective frequency divider circuit (18, 19). The frequency divider circuits have different division ratios so that the output signals thereof have substantially the same frequency. <IMAGE>
Patent GB-2092133-B (GB)
Title: Pyridine and pyrimidine intermediates
IPC: B29D99/00
Filed: 1980-10-13
Granted: 1983-03-16
Abstract: A series of 4-(2-hydroxyethylthiomethyl)pyridines and related compounds, and their pharmaceutically acceptable acid addition salts, having antiinflammatory and immunoregulatory activity are disclosed. Preferred compounds include 4-(2-hydroxyethylthiomethyl)pyridine itself, as well as 4-(2-hydroxyphenylthiomethyl)pyridine, 4-(2-hydroxy-1-propylthiomethyl)pyridine, 4-(3-hydroxy-2-butylthiomethyl)pyridine, 4-(2-hydroxyethylthiomethyl)pyrimidine, the acetate esters corresponding to the above compounds, and 4-(2,3-dihydroxy-1-propylthiomethyl)pyridine.
Patent GB-2179196-B (GB)
Title: Electric cables
Inventor: BALL EDMUND HUGH
IPC: H02G1/14
Filed: 1985-08-08
Granted: 1989-01-11
Abstract: An electric cable having a current carrying conductor provided with an extruded polymeric insulating layer, has a layer of a high permittivity material extruded over the whole length of the insulating layer, which layer is covered with semi-conducting tape in contact therewith.
Patent GB-2183838-B (GB)
Title: Depth and decompression diving gauge
Inventor: BESSON RENE
IPC: G04B19/28
Filed: 1986-11-17
Granted: 1989-10-04
Abstract: The gauge comprises a case (10) having a face (11) bearing reference marks disposed over an arc of a circle centred on the axis of rotation of a hand (12). A first zone of the face consists of sectors (33), (34) over which the hand moves according to the depth of the diver. Between the sectors (33) (34) is a sector (35) forming the second zone of the face, in which the hand moves whilst measuring time during the diver's ascent. This sector 40 corresponding to the three metre stage is covered in the direction of the arrow A in thirty minutes when the diver ascends. A number of the zones may be provided to indicate the required decompression period at several depths. <IMAGE>