baber/WOPTO huggingface dataset:
Patent CA-3100725-A1 (CA)
Inventor: TUMAN WILLIAM
IPC: B60N2/66
Filed: 2019-08-16
Abstract: A lumbar support device for a vehicle seat permits vertical and fore-aft adjustment of the support or forces exerted on the back of an operator seated on the vehicle seat. The lumbar support device includes a lumbar panel resiliently flexibly attached to the seat frame and/or seat shell to permit fore and aft movement of the lumbar panel relative to the seat back, the lumbar panel arranged to bear against the seat back, and a cam element having a cam surface bearing against the lumbar panel to apply force to the lumbar panel toward the seat back, the cam element supported on the seat frame and/or seat shell for movement relative to the lumbar panel and relative to the seat shell and/or seat frame, the cam element configured to vary the force applied to the seat back based on the movement of the cam element.
Patent CA-3100954-A1 (CA)
Title: Cyanotriazole compounds and uses thereof
Inventor: JIRICEK JAN
IPC: C07D403/06
Filed: 2019-06-18
Abstract: The present invention provides a compound of Formula (I), or a pharmaceutically acceptable salt thereof: (I) wherein R1, R2, R3, and R4 are as defined herein. The present invention further provides therapeutic uses of these compounds, for example against human African typanosomiasis; pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.
Patent CA-3102055-A1 (CA)
Title: Car nk cells
Inventor: SPANHOLTZ JAN
IPC: C12N5/0783
Filed: 2019-05-29
Abstract: The present invention relates to the field of manufacturing of Natural Killer (NK) Cells genetically modified with lenti viral vectors carrying a polynucleotide coding for a Chimeric Antigen Receptors (CARs). The present invention further relates to CAR - NK cells obtained with the method and use of the CAR - NK cells in medicine, in particular for use in a method of treating cancer.
Patent CA-3103457-A1 (CA)
Title: Grey water treatment systems and methods of treating grey water
Inventor: VALKIESER ARTHUR J L
IPC: E03D5/00
Filed: 2018-07-03
Abstract: The invention relates to a grey water treatment system comprising: a first tank that is configured to receive grey water via a grey water supply conduit and that comprises an overflow; a second tank that is configured to store grey water; and at least one transfer conduit that is configured to at least transfer grey water between the first tank and the second tank; and a control that is configured to maintain a water level in said first tank sufficiently close to the overflow to allow floating contaminants to pass over the overflow Furthermore, the invention relates to a method of treating grey water, comprising the steps of: receiving grey water in a first tank of a grey water treatment system; transferring grey water via at least one transfer conduit between the first tank and a second tank of said grey water treatment system; and controlling a water level in said first tank sufficiently close to an overflow of said first tank to allow floating contaminants to pass over the overflow.
Patent CA-3105662-A1 (CA)
Title: Composes derives de 1,3,4-oxadiazole utilises en tant qu'inhibiteur de l'histone desacetylase 6, et composition pharmaceutique les comprenant
Inventor: LEE CHANG SIK
IPC: A61P3/00
Filed: 2019-07-25
Abstract: La présente invention concerne de nouveaux composés ayant une activité inhibitrice de l'histone désacétylase 6 (HDAC6), des isomères optiques ou des sels pharmaceutiquement acceptables de ceux-ci, une utilisation pharmaceutique associée, et un procédé de préparation correspondant. Les nouveaux composés, selon la présente invention, leurs isomères optiques ou leurs sels pharmaceutiquement acceptables ont une activité inhibitrice de l'histone désacétylase 6 (HDAC6), et sont efficaces pour prévenir ou traiter des maladies associées à HDAC6, notamment des maladies infectieuses ; un néoplasme ; une sécrétion interne ; des maladies nutritionnelles et métaboliques ; des troubles mentaux et comportementaux ; des maladies neurologiques ; des maladies oculaires et annexielles oculaires ; des maladies circulatoires ; des maladies respiratoires ; des maladies digestives ; des maladies de tissu cutané et sous-cutané ; des maladies du système musculo-squelettique et des maladies du tissu conjonctif ; une tératose ou des difformités, et une aberration chromosomique.
Patent CA-3107462-A1 (CA)
Inventor: CARDINAL JACOB J
IPC: A61B5/055
Filed: 2019-07-24
Abstract: The present disclosure describes methods and systems for use in the production of adeno-associated virus (AAV) particles and AAV formulations, including recombinant adeno-associated virus (rAAV) particles and formulations. In certain embodiments, the present disclosure presents methods and systems for clarifying, purifying, formulating, filtering and processing AAV particles and AAV formulations. The present disclosure also describes compositions, methods and processes for the design, preparation, manufacture, use and/or formulation of AAV particles comprising modulatory polynucleotides, e.g., polynucleotides encoding small interfering RNA (siRNA) molecules which target the Huntingtin (HTT) gene (e.g., the wild-type or the mutated CAG-expanded HTT gene). Methods for using formulated AAV particles comprising modulatory polynucleotides to inhibit the HTT gene expression in a subject with a eurodegenerative disease (e.g., Huntington's Disease (HD)) are also disclosed.
Patent CA-3107956-A1 (CA)
Inventor: JAHNS STEVEN KARL
IPC: B60K35/00
Filed: 2021-02-02
Abstract: Systems, methods and computer readable storage media provide a flexible and variability-accommodating instrument cluster for display on an in-vehicle screen and a user experience interaction model for providing vehicle status-related information via the instrument cluster. The instrument cluster may be shown in a minimized content view, basic content view, or enhanced content view, wherein each content view may include a varying range of displayed information based on a layout template. The driver can easily scroll between the various content views while driving. The instrument cluster may alternatively be shown in a favorites view, amongst a plurality of preconfigured favorites views associated with different drivers, the favorites view including a user-selected set of gauges in a user-selected layout. A  steering wheel-based shortcut control is provided that can be assigned to a changeable parameter and used to toggle the parameter in association with an instrument cluster display element while driving.
Patent CA-3109436-A1 (CA)
Inventor: SUGINO MASAAKI
IPC: F16L15/04
Filed: 2019-07-01
Abstract: A threaded connection for steel pipes includes a pin including a tapered male thread part and a shoulder part, and a box including a tapered female thread part and a shoulder part. When the shoulder parts are in contact with each other, roots of the male thread part are in contact with crests of the female thread part while interfering with the crests, and clearances are provided between crests of the male thread part and roots of the female thread part.  The crests of the male thread part are formed in a convex curve that is tangent to both first corner portions which are formed in an arc that connect the crests and load flanks, and second comer portions which are formed in an arc that connect the crests and stabbing flanks. A solid lubricant coating is provided on the surface of the male thread part.
Patent CA-3110188-A1 (CA)
Inventor: MITROPOLSKAYA NATALIA GEORGIEVNA
IPC: F16B33/00
Filed: 2018-08-31
Abstract: This invention generally relates to the field of nonferrous metallurgy, namely to titanium alloy materials with specified mechanical properties for manufacturing the aircraft fasteners. A stock for high strength fastener is manufactured from wrought titanium alloy containing, in weight percentages, 5.5 to 6.5 Al, 3.0 to 4.5 V, 1.0 to 2.0 Mo, 0.3 to 1.5 Fe, 0.3 tol.5 Cr, 0.05 to 0.5 Zr, 0.15 to 0.3 O, 0.05 max. N, 0.08 max. C, 0.25 max. Si, balance titanium and inevitable impurities, having the value of aluminum structural equivalent [Al]eq in the range of 7.5 to 9.5, and the value of molybdenum structural equivalent [Mo]eq in the range of 6.0 to 8.5, where the equivalents are defined by the following equations: [Al]eq =[Al]+[O]x l0+ [Zr]/6; [Mo]eq =[Mo]+[V]/1.5+[Cr]xl.25+[Fe]x2.5. A manufacturing method for a stock for high strength fastener includes melting of titanium alloy ingot, production of forged billed from ingot at beta and/or alpha-beta phase field temperatures, hot rolling at a heating temperature of beta and/or alpha-beta phase field to produce a round stock, subsequent annealing of a rolled stock at a temperature of 550°C to 705°C (1022°F to 1300°F) for at least 0.5 hour followed by drawing to produce a wire with diameter up to 10 mm (0.394 inches) and subsequent annealing at a temperature of 550°C to 705°C (1022°F to 1300°F) for at least 0.5 hour. A technical result is production of a titanium alloy stock for high strength fastener having high ultimate tensile strength and double shear strength while maintaining a high level of plastic properties in the annealed condition.12 claims, 5 illustrations.
Patent CA-3112074-A1 (CA)
Title: Acoustic ceiling panel, method of manufacture and acoustic ceiling system
Inventor: ZUO YANJIA
IPC: E04B9/04
Filed: 2021-03-15
Abstract: The present disclosure relates generally to acoustic panels, for example, suitable for use in a ceiling to control sound. The present disclosure relates more particularly to an acoustic ceiling panel including an acoustic substrate formed of a porous material having an air flow resistivity of at least 300 kPa*5/m2. The acoustic substrate includes an upper face and a lower face with a pattern of perforations formed therein, where the pattern of perforations covers at least 6% of the area of the lower face. The acoustic ceiling panel also includes a backing layer disposed over the upper face of the acoustic substrate and a veil disposed over the lower face.
Patent CA-3113189-A1 (CA)
Inventor: ROBINSON RACHEL
IPC: B22C9/22
Filed: 2021-03-24
Abstract: A cast for producing end plates for a pump assembly, the cast comprising a base portion and a pair of projections, the pair of projections providing material to machine bearing assembly housings for accommodating drive and idler shafts in the pump assembly. Also provided is an inner plate bushing for an end plate in a pump assembly, the inner plate bushing comprising a collar extending from a flange, the collar to be inserted into a mounting recess in the end plate with the flange seating flush with a surface of the end plate, the surface area of an end of the collar being larger than an inner surface of the flange.
Patent CA-3118091-A1 (CA)
Title: Systems and methods for forming a subterranean borehole
Inventor: STAACK DAVID
IPC: E21B7/15
Filed: 2019-10-30
Abstract: Systems and methods for drilling a borehole are disclosed. In an embodiment, the system includes a drill bit and a plasma inducing apparatus coupled to the drill bit. The plasma inducing apparatus is configured to generate plasma.
Patent CA-3119291-A1 (CA)
Inventor: ZHANG HONG
IPC: A01N35/06
Filed: 2019-11-12
Abstract: Encapsulation of cyclohexanediones process and product. A composition particularly adapted for herbicidal use is described, including biopolymer micro-capsules containing one or more cyclohexanediones encapsulated therein, resulting in enhanced chemical stability and dispersibility of the encapsulated cyclohexanediones for such use. A complex coacervation method of forming such microcapsules is also described.
Patent CA-3119352-A1 (CA)
Inventor: GIRAUD WILLIAM JULIUS MCPHIL
IPC: G02B6/44
Filed: 2019-10-23
Abstract: L'invention concerne un dispositif de stationnement de fibre optique comprend une paroi de support ayant des côtés avant et arrière, et comprend également au moins une monture s'étendant vers l'extérieur à partir du côté arrière de la paroi de support et définissant un premier plan. Le dispositif de stationnement de fibre optique comprend en outre une plateforme s'étendant vers l'extérieur à partir du côté avant de la paroi de support et définissant un second plan, la plateforme comprenant une pluralité de coins de retenue de connecteur. Chacun des coins de retenue de connecteur s'étend le long d'un axe correspondant parallèle au second plan et coupe le premier plan à un angle aigu.
Patent CA-3119967-A1 (CA)
Title: Moteur a aimants permanents
Inventor: SETERNES HANS
IPC: H02K53/00
Filed: 2019-11-12
Abstract: Un moteur à aimants permanents comprend un arbre d'entraînement (200) relié à un générateur d'énergie (210). Au moins une première unité d'alimentation (100A) et une seconde unité d'alimentation (100B) sont disposées autour de l'arbre d'entraînement (200) en étant mutuellement délimitées sur l'axe longitudinal de l'arbre d'entraînement (200) par une plaque de protection (207). Chaque unité d'alimentation (100A, 100B) présente un premier disque rotatif (101) et un second disque rotatif (102), inclinés entre eux par rapport à l'axe longitudinal de l'arbre d'entraînement (200). Une plaque de stator (203) est disposée entre le premier et le second disque rotatif (101, 102) et présente une piste de traction (212) le long de sa périphérie, et une piste de poussée (213) sur le côté diamétralement opposé du disque rotatif (101, 102). Au moins six paires d'aimants permanents (300) ayant un aimant de traction (300 ) et un aimant de poussée (300+) sont disposées à une distance relative égale le long de cercles de fixation respectifs à la même distance radiale de l'arbre d'entraînement (200) que la piste de traction (212) et la piste de poussée (213), respectivement.
Patent CA-3121718-A1 (CA)
Title: Dendrite growth prevention in a rechargeable battery
Inventor: DANINO AVIEL
IPC: H01M50/454
Filed: 2019-12-03
Abstract: Rechargeable batteries and corresponding methods are provided, in which zinc dendrite growth to a compartment between a zinc -based anode and a separator of a rechargeable battery is limited, by preventing zincate anions from diffusing outside of the compartment. Separators limiting dendrite growth may comprise ion-selective membrane(s) configured to be permeable to charge transfer cations of the alkaline electrolyte and impermeable to hydrated zincate anions. The membrane(s) may be reinforced and/or support internal compartment(s) with electrolyte lacking zincate ions. More generally, separators are provided, which are permeable to charge transfer ions but impermeable to metal ions, and limit the latter to the anode compartment in which the metal ions may be deposited in a manner that does not form dendrites which can compromise the structural and functional integrity of the battery cell.
Patent CA-3123647-A1 (CA)
Title: Oral care compositions comprising a polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymer, and methods for the same
Inventor: YUAN SHAOTANG
IPC: A61Q11/00
Filed: 2019-12-16
Abstract: An oral care composition and methods for preparing the oral care composition are disclosed. The oral care composition may include a carrier and a structure-building agent. The carrier may be present in an amount of from about 0.01 wt% to about 99 wt%. The structure- building agent includes a polyvinyl capralactam-polyvinyl acetate- polyethylene glycol graft copolymers (PCA-PVA-PEG), and may be present in an amount of from about 0.01 wt% to about 60 wt%, based on a total weight of the oral care composition.
Patent CA-3129841-A1 (CA)
Title: Cyclic molecules as bruton's tyrosine kinase inhibitor
Inventor: WANG ZHAOYIN
IPC: A61K31/519
Filed: 2020-01-16
Abstract: The present invention describes novel molecules having protein tyrosine kinase inhibitory activity, and methods of synthesizing and using the compound. Specifically, the present invention describes a compound of formula (A) or a pharmaceutically acceptable salt, a hydrate or a solvate thereof, and methods of synthesizing and using the compound.
Patent CA-3131074-A1 (CA)
Title: Procede de prevention de transfert de chaleur pour systeme de chauffage de puits de forage
Inventor: HANSEN HENNING
IPC: E21B43/24
Filed: 2019-11-20
Abstract: La présente invention concerne un procédé d'isolation thermique d'un câble d'alimentation (9) ou d'un autre équipement sensible à la température d'un outil de puits de forage qui comprend un élément de chauffage (1). L'outil de puits de forage est déployé à une extrémité du câble d'alimentation (9) dans un puits. Un limiteur de débit (4) est déployé dans un espace annulaire entre l'élément de chauffage (1) et un élément tubulaire de puits de forage (2). L'élément de chauffage (1) est espacé axialement du câble d'alimentation (9) de telle sorte que l'élément de chauffage (1) est disposé sur un côté du limiteur de débit (4) et qu'une connexion au câble d'alimentation (9) est disposée sur un autre côté du limiteur de débit (4). Un isolant thermique est introduit dans l'espace annulaire sur un côté du limiteur de débit (4) et l'élément de chauffage (1) est mis en fonctionnement.
Patent CA-3135198-A1 (CA)
Inventor: LEE DEAN ANTHONY
IPC: A61K38/46
Filed: 2020-03-27
Abstract: Disclosed are methods for genetically engineering cells using Adeno-associated viral (AAV) delivery of a CRISPR/CAS9 system and ribonucleoproteins for integration. In some aspects, disclosed herein are AAV plasmids for performing said methods
Patent CA-3135440-A1 (CA)
Title: Process for preparing [(3-hydroxypyridine-2-carbonyl)amino]alkanoic acid, derivatives and uses thereof
Inventor: LANTHIER CHRISTOPHER M
IPC: C07D213/81
Filed: 2012-06-05
Abstract: The present invention discloses [(5-aryl/heteroaryl-3-hydroxypyridine-2-carbonyl)amino]-alkanoic acid derivatives having the formula (see above formula) wherein M is a salt forming cation and N represents the cationic charge on M;  A is phenyl; R10 is hydrogen, halogen, alkyl, methoxy, cyano, nitro, trifluoromethyl, carbamoyl, pyrrolidine-1-carbonyl, cyclopropanecarbonylamino, 3-chloro-6-methyl, or 2-chloro-5-methyl; L is a linking unit having the formula: ¨(CR7aR7b)n-;  R7a and R7b are each independently: i) hydrogen; or ii) C1-C6 linear, C3-C6 branched or C3-C6 cyclic alkyl; R8 is hydrogen, methyl, or ethyl; and n is an integer from 1 to 4. The disclosed compounds are useful as prolyl hydroxylase inhibitors or for treating conditions wherein prolyl hydroxylase inhibition is desired.
Patent CA-3136450-A1 (CA)
Title: Anticorps ciblant la cd47 humaine
Inventor: KURTZMAN AARON
IPC: C07K16/30
Filed: 2020-04-17
Abstract: L'invention concerne des anticorps isolés qui se lient à la CD47 et la bloquent, des vecteurs comprenant une molécule d'acide nucléique codant pour une séquence d'acides aminés de la molécule de liaison, et des cellules hôtes contenant lesdits vecteurs. L'invention concerne également des procédés de préparation des anticorps, des compositions pharmaceutiques contenant les anticorps, et des méthodes d'utilisation de tels anticorps, fragments d'anticorps et dérivés et polypeptides, tels que dans le traitement de maladies, notamment le cancer.
Patent CA-3137601-A1 (CA)
Title: Systems and methods for dynamic repositioning of inventory
Inventor: CACIOPPO CHRISTOPHER
IPC: G06Q10/08
Filed: 2021-11-04
Abstract: Disclosed herein are systems and methods for dynamically repositioning inventory items in a space. The exemplary systems may be configured to receive a signal indicating a change in demand for a product, in which a plurality of items of the product are positioned at a first location within the space. The systems may be configured to determine a second location within the space for positioning at least some items such that a collection time is reduced. The systems may be further configured to generate a route for an autonomous vehicle that includes the first and second locations, as well as a third location where an item for an order is positioned. The systems may then trigger navigation of the autonomous vehicle, based on the route, to reposition the items from the first location to the second location and to collect the item for the order.
Patent CA-3137655-A1 (CA)
Inventor: STUCCHI MARCO
IPC: E04H17/16
Filed: 2019-05-14
Abstract: L'invention concerne un ensemble d'ancrage d'enceintes (100) comprenant au moins une grille laminaire (101), qui comporte au moins un fil rigide (101a), et au moins un poteau (102), servant à supporter la grille (101) dans une orientation verticale. L'ensemble comprend au moins une broche (2) pourvue d'une tête (3) et d'une tige (4), la tige (4) étant conçue pour être insérée dans un trou (102a) ménagé dans le poteau (102). L'ensemble (1) comprend en outre au moins une pince qui comprend une cavité (8) qui est conçue pour recevoir la tige (4) avec interférence. Le fil rigide (101a) peut être serré dans la pince. L'ensemble (1) comprend également au moins une tige (9) au moins partiellement filetée, qui peut être vissée dans un filetage femelle prévu dans la broche (2) avec pour effet un serrage mutuel de la pince.
Patent CA-3141197-A1 (CA)
Title: Optical resonator device with crossed cavities for optically trapping atoms, and applications thereof in an optical atomic clock, a quantum simulator or a quantum computer
Inventor: BLATT SEBASTIAN
IPC: G04F5/14
Filed: 2019-06-19
Abstract: An optical resonator device (100) with crossed cavities, in particular being configured for optically trapping atoms, comprises a first linear optical resonator (10) extending between first resonator mirrors (11A, 11B) along a first resonator light path (12) and supporting a first resonator mode, a second linear optical resonator (20) extending between second resonator mirrors (21A, 21B) along a second resonator light path (22) and supporting a second resonator mode, wherein the first and second resonator light paths (12, 22) span a main resonator plane, and a carrier device carrying the first and second resonator mirrors (11A, 11B, 21A, 21B), wherein the first and second resonator mirrors (11, 21) are arranged such that the first and second resonator modes cross each other for providing an optical lattice trap (1) in the main resonator plane. The carrier device comprises a monolithic spacer body (30) being made of an ultra-low-expansion material and comprising first carrier surfaces (31) accommodating the first resonator mirrors (11A, 11B) and second carrier surfaces (32) accommodating the second resonator mirrors (21A, 21B), wherein the first resonator light path (12) extends through a first spacer body bore (33) in the spacer body (30) between the first carrier surfaces (31), and the second resonator light path (22) extends through a second spacer body bore (34) in the spacer body (30) between the second carrier surfaces (32). Furthermore, an atom trapping method for creating a two-dimensional arrangement of atoms and an atom trap apparatus, like an optical atomic clock, a quantum simulation and/or a quantum computing device are described.
Patent CA-3143033-A1 (CA)
Title: Data serialization extrusion for converting two-dimensional images to three-dimensional geometry
Inventor: BARKER JEREMIAH TIMBERLINE
IPC: G06T19/00
Filed: 2020-06-12
Abstract: Systems, methods, and devices for data serialization extrusion of input images and raw input data. A method includes determining an input image comprising one or more lines and generating a bitmap based on the input image. The method includes performing edge detection on the bitmap to identify the one or more lines in the input image by applying a growth algorithm to pixels of the bitmap. The method includes calculating a pixel width of each of the one or more lines in the input image.