baber/WOPTO huggingface dataset:
Patent NZ-514017-A (NZ)
Title: Novel dipeptide compound and medicinal use thereof
Inventor: MIMOTO TSUTOMU
IPC: A61P31/18
Filed: 2000-12-28
Abstract: A dipeptide compound as shown by formula (I) wherein: R1, R2 and R3 independently represent a linear or branched, saturated or unsaturated lower alkyl group, alkoxyl group, alkyl amino group, or dialkyl amino group having 1-4 carbon atoms (with a carbon atom being either replaced by an oxygen atom or not), a halogeno group, or a hydrogen atom, provided that all of the R1, R2 and R3 are not a hydrogen atom at the same time, R2 and R3 may form a ring together; R4 represents a linear or branched lower alkyl group having 1-4 carbon atoms or a hydrogen atom; X is a methylene group or a sulfur atom; Y represents a five or six member monocyclic or polycyclic hydrocarbon group, a heterocyclic group having a structure in which one or more carbon atom in the monocyclic or polycyclic hydrocarbon group is replaced by a hetero atom, an aryloxyalkyl group having 12 or less carbon atoms, in which one or more carbon atoms in the monocyclic or polycyclic hydrocarbon group is replaced by a hetero atom, an aryloxyalkyl group having 12 or less carbon atoms, in which the monocyclic or polycyclic hydrocarbon group or the aryloxyalkyl aromatic ring may be substituted with an alkyl group, alkoxy group, ahlogeno group, amino group or hydroxyl group; and Z represents an aliphatic hydrocarbon group having 1-6 carbon atoms or an aromatic hydrocarbon group having 12 or less carbon atoms in which the aromatic ring may be substituted with an alkyl group, alkoxy group, or halogeno group, or one or more carbon atom in the aromatic hydrocarbon group may be replaced by a hetero atom. Also disclosed is the use of said compound in the preparation of an anti-AIDS medicine.
Patent NZ-526995-A (NZ)
Title: A composition capable of treating chronic stable angina pectoris, comprising radix salviae miltorrhizaem panax notoginseng and borneol
Inventor: YAN XIJUN
IPC: B01J2/00
Filed: 2001-12-18
Abstract: A composition capable of treating chronic stable angina pectoris, comprising 5-40% of water soluble phenolic acid extracted from Radix Salviae Miltorrhizae, 1-10% water soluble saponin extracted from Panax Notoginseng and 1-5% of Borneol.
Patent NZ-528974-A (NZ)
Title: Cladding apparatus and methods, typically for roofing, with cladding interengaging with battens
Inventor: PODIRSKY BERNHARD
IPC: E04D3/32
Filed: 2002-04-24
Abstract: There is provided a roof cladding consisting of elements of recycled plastics, material comprising a body portion, a batten engagement portion located at the leading edge of the body portion and a batten back stop being a transverse rib located on the underside of the body portion at a spacing from the batten engagement means determined by the pitch or spacing of the roofing battens. The batten engagement portion comprises a downward depending web adapted to bear on the up-slope face of the roofing batten, and a lower web extending therefrom to lay adjacent the under surface of the batten in use. The edge of the lower web toward the leading edge is provided with a locking lug in the form of a ridge adapted to pass the batten against the resilient bias of the downward depending web and the lower web, to engage the leading face of the roof batten. The clearance between the body portion and the lower web is such that the space accommodates the trailing edge of an adjacent roofing element to trap the trailing edge between the underside of the body portion and the batten. Further installed security is provided by the backstop engaging the upper leading edge of the adjacent batten.
Patent NZ-531117-A (NZ)
Title: Compositions and methods relating to novel benzodiazepine compounds and targets thereof
Inventor: GLICK GARY D
IPC: G01N33/15
Filed: 2002-08-15
Abstract: The disclosure relates to benzodiazepine derivatives and methods of using benzodiazepine derivatives as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, and hyperproliferation, and the like. The method involves: a. providing: i. target cells having mitochondria; ii. an agent that binds to oligomycin sensitivity conferring protein; and b. exposing said cells to said agent under conditions such that said agent binds to said oligomycin sensitivity conferring protein so as to increase superoxide levels or alter cellular ATP levels in said cells wherein the target cells do not form a human.
Patent NZ-545455-A (NZ)
Title: Peptides and compounds that bind to thrombopoietin receptors
Inventor: MACDONALD BRIAN R
IPC: A61K47/48
Filed: 2004-08-13
Abstract: Disclosed is a peptide compound that binds to a thrombopoietin receptor. The peptide is of the form (H-IEGPTLRQ(2-Nal)LAARX10)2K-NH2, and X10 is selected from sarcosine or â-alanine. Also disclosed is a peptide compound that binds to thrombopoietin receptor, which is less than about 8000 daltons, has a binding affinity to thrombopoietin receptor as expressed by an IC50 of no more than about 100 µM, and has the following form: X9X8GX1X2X3X4X5X6X7 where X9 is A, C, E, G, I, L, M, P, R, Q, S, T, or V; X8 is A, C, D, E, K, L, Q, R, S, T, or V, X1 is C, L, M, P, Q, V; X2 is F, K, L, N, Q, R, S, T or V; X3 is C, F, I, L, M, R, S, V or W; X4 is any of the 20 genetically coded L-amino acids; X5 is A, D, E, G, K, M, Q, R, S, T, V or Y; X7 is C, G, I, K, L, M, N, R or V, and X6 is â-(2-naphthyl)alanine. Both compounds are disclosed to be covalently attached to a hydrophilic polymer.
Patent NZ-546072-A (NZ)
Title: Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
Inventor: WANG XINWEN
IPC: G01N33/53
Filed: 2004-09-22
Abstract: Disclosed is a method of producing a solid microparticle having nucleic acid molecules attached, said microparticle being made of a polymer, a polymer resin, glass or latex, wherein a surface of the microparticle is coated with Bovine Serum Albumin under conditions whereby the Bovine Serum Albumin has an increased number of sites for covalent attachment of nucleic acid molecules, comprising: covalently attaching Bovine Serum Albumin to said surface at a temperature of about 65° C; and covalently attaching nucleic acid molecules to said Bovine Serine Albumin.
Patent NZ-553241-A (NZ)
Title: Medium and culture of pluripotent stem cells
Inventor: THOMSON JAMES A
IPC: C12N5/02
Filed: 2005-09-08
Abstract: Disclosed is a method for culturing human pluripotent stem cells in an undifferentiated state on a matrix without the need for feeder cells or conditioned medium, the method comprising the step of: culturing the human pluripotent stem cells on a matrix in a medium absent feeder cells and conditioned media, the medium comprising salts, vitamins, amino acids, glucose, a fibroblast growth factor, transforming growth factor beta, and at least one member selected from gamma amino butyric acid, pipecolic acid, and lithium, activin or a lithium substitute that stimulates the Wnt pathway, in sufficient amounts to maintain the cells in an undifferentiated state through multiple successive culture passages.
Patent NZ-554239-A (NZ)
Title: A process for manufacturing a breathable chemically resistant polymer material
Inventor: BEADLE BRIAN ALAN
IPC: C08G81/02
Filed: 2005-09-30
Abstract: Disclosed is a process for providing a breathable chemically resistant polymer material form comprising the step of: blending by extrusion: at least 50% by weight of one or more hydrophilic polymers being selected from the group comprising: Poly Vinyl Alcohols, Ethylene Vinyl Alcohols, Poly Hydroxyethyl Methacrylates, Poly Ethylene Oxides, Poly Ether block Amides, Breathable Thermoplastic Elastomers, and Polyurethanes; as a first component, and between 5 and 50% by weight of one or more neutralising chemicals (such as polyethyleneimine) as a second component, in the complete or substantial absence of water. In the absence of water, the components will not be aqueous solutions, thus the components can be used in blending processes, and it is able to form many other shapes and forms of material other than laminates on substrates.
Patent NZ-555452-A (NZ)
Title: Interactive data transfer for financial transactions
Inventor: URQUHART CRAIG ALEXANDER
IPC: G06Q30/00
Filed: 2007-05-25
Abstract: A central processing station for interactive data transfer in the form of providing financial data analysis to a user via a portable device is disclosed. The central processing station is configured to operate in accordance with the following steps: a) receiving an electronic message containing financial data from a user using a portable device; b) extracting a monetary value from the electronic message; c) extracting an identifier for the user from the electronic message; d) analysing the monetary value to determine a set of payments and; e) sending a return electronic message containing the payment information to the user.
Patent NZ-560383-A (NZ)
Title: A container with stackable and lockable lids
Inventor: TUCKER EDWARD B
IPC: B65D21/00
Filed: 2006-02-22
Abstract: A container is disclosed which comprises a first cover comprising a first closure portion, an engagement portion, and an alignment portion. The first closure portion is sealingly engageable with a second closure portion of a base so that when the first and second closure portions are engaged with each other, the first cover and the base define a substantially sealed storage area. Adjacently stacked covers in a vertically aligned cover stack are configurable between a first, locked configuration and a second, unlocked configuration. The engagement portion of the first cover when configured in the first, locked configuration, includes an upper protrusion engageable with the engagement portion of a second cover wherein the second cover includes a lower protrusion. The lower protrusion fits over and receives the upper protrusion to lock the covers together in the first locked configuration. The engagement portion of the first cover is engageable with the engagement portion of the second cover when configured in the second, unlocked configuration, to form an aligned, nested cover stack. The first cover rests on an outer wall of the second cover and the first cover includes a lower shoulder and the second cover includes an upper shoulder where the lower shoulder of the upper cover rests on the upper shoulder of the lower cover. The base comprises a bottom, a peripheral sidewall extending from the bottom, an open top, and the second closure portion.
Patent NZ-563191-A (NZ)
Title: Substituted indole compounds having NOS inhibitory activity
Inventor: MADDAFORD SHAWN
IPC: C07D401/04
Filed: 2006-04-13
Abstract: Disclosed is a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein R1 is H, optionally substituted C1-6 alkyl, optionally substituted C1-4 alkaryl, optionally substituted C1-4 alkheterocyclyl, or optionally substituted C1-4heterocyclyl, each of R4 and R7 is H, F, C1-6 alkyl, or C1-6 alkoxy, R5 is H, R5AC(NH)NH(CH2)r5 or R5BNHC(S)NH(CH2)r5, r5 is an integer from 0 to 2, R6 is H, R6AC(NH)(CH2)r6 or R6BNHC(S)NH(CH2)r6, r6 is an integer from 0 to 2, and wherein the rest of the substituents are as defined in the specification. Also disclosed is the use of the compound to treat conditions caused by the action of nitric oxide synthase such as migraine headache (with or without aura), chronic tension type headache (CTTH), migraine with allodynia, neuropathic pain, post-stroke pain, chronic headache, chronic pain, acute spinal cord injury, diabetic neuropathy, trigeminal neuralgia, diabetic nephropathy, an inflammatory disease, stroke, reperfusion injury, head trauma, cardiogenic shock, CABG associated neurological damage, HCA, AIDS associated dementia, neurotoxicity, Parkinson's disease, Alzheimer's disease, ALS, Huntington's disease, multiple sclerosis, metamphetamine-induced neurotoxicity, drug addiction, morphine/opioid induced tolerance, dependence, hyperalgesia, or withdrawal, ethanol tolerance, dependence, or withdrawal, epilepsy, anxiety, depression, attention deficit hyperactivity disorder, or psychosis.
Patent NZ-567860-A (NZ)
Title: Uses of IL-23 agonists and antagonists that specifically bind to IL-23R
Inventor: OFT MARTIN
IPC: A61K39/395
Filed: 2004-03-09
Abstract: Disclosed is the use of an antagonist of IL-23 for the manufacture of a medicament for the treatment of tumors comprising tumor cells, wherein the antagonist of IL-23 comprises an antibody, or antigen binding fragment thereof, that specifically binds to IL-23R (SEQ ID NO: 6). Also disclosed are methods of determining whether tumors express IL-23 receptor. (62) Divided Out of 541898
Patent NZ-571008-A (NZ)
Title: Compact gym with pedal cycle machine rotatable for arm flexion or extension exercises
Inventor: PIGGINS DARREN
IPC: A63B21/06
Filed: 2007-02-06
Abstract: Disclosed in this specification is a compact gym that comprises both a recumbent exercycle and a pulley system. The recumbent exercycle may be rotated by 180 degrees to offer users a greater variety of workouts. The compact gym's various components may be folded into a cupboard for storage.
Patent NZ-571128-A (NZ)
Title: Calcium enrichment compositions for adding to food or drink comprising citrate and a metal, methods of production thereof, and their use
Inventor: PAIKIN MICHAEL
IPC: A23L11/00
Filed: 2007-03-22
Abstract: Disclosed is a calcium rich composition comprising: (i) at least one source of calcium; (ii) at least one source of metal selected from an alkaline metal other than calcium or an alkali metal; and (iii) at least one source of citrate; wherein the composition has a bulk density of less than 0.6 g/cm3, comprises at least 13% (wt/wt) calcium and at least 63% (wt/wt) of citrate on dry weight basis. Also disclosed are food products, such as beverages, containing this composition. Also disclosed is a method of producing the composition.
Patent NZ-574331-A (NZ)
Title: Liquid compositions of calcium acetate
Inventor: TARALLO STEPHEN C
IPC: A01N37/00
Filed: 2007-07-20
Abstract: Disclosed is an oral dosage form of calcium acetate comprising a liquid pharmaceutical composition comprising an aqueous solution of: (a) 7-21% calcium acetate (w/v), (b) an artificial sweetener selected from the group consisting of sucralose, acesulfame potassium, aspartame and saccharin, (c) a polyol selected from the group consisting of sorbitol, glycerine, propylene glycol, xylitol, maltilol and combinations thereof, and (d) a taste masking agent comprising monoammonium glycyrrhizinate. Also disclosed is the use of the said oral dosage form for the preparation of a medicament for binding phosphorus within the gastrointestinal tract of an individual.
Patent NZ-576937-A (NZ)
Title: Fire Seal for a Wall System Suitable for Inter-tenancy Installation
Inventor: LAVENDER DOUG
IPC: E04B1/76
Filed: 2009-05-13
Abstract: A track member for use in a fire-rated wall system is disclosed. The track member is adapted to be secured to a support surface and receive therein at least one shaft liner. The track member includes opposed, spaced-apart first and second flanges extending from a web. At least one of the flanges is foldable with respect to the web. The track member further includes a fire-proofed element attached thereto. (61) Addition to 574522
Patent NZ-577025-A (NZ)
Title: Suspended system that allows for rail sag which reduces vibration when a carrage travels over a rail joint
Inventor: BISCHOFBERGER MARKUS
IPC: B61B3/00
Filed: 2009-05-15
Abstract: A rail system for carrying individuals down from a mountain station into a valley station is disclosed. The system uses a moving joint (5) between a running rail's sub-rails (4) to cushion the transition of a carriage between the sub-rails (4). The running rail is fastened on to a supporting cable (2) at a distance from the ground via suspension means (16, 17). In the region of the joints (5), the sub-rails (4) are elevated in relation to their central region. A top gap (25) between each side of the joint (5) allows for the downward movement of the transition between sub-rails (4) when the suspended carriage transitions thought that region.
Patent NZ-580023-A (NZ)
Title: Preform for bag in container with additive in one of inner or outer layers to enable layers to reach blow moulding temperatures simultaneously
Inventor: VAN HOVE SARAH
IPC: B29B11/14
Filed: 2008-04-18
Abstract: The present disclosure relates to an integrally blow-moulded bag-in- container (2) and preform (1' ) for blow-moulding the bag-in-container. An inner layer (11) and an outer layer (12) are used, wherein the preform forms a two-layer container upon blow-moulding, and wherein the obtained inner layer of said container releases from the thus obtained outer layer upon introduction of a gas at a point of interface (14) between the two layers. At least one of the inner and outer layers includes at least one additive allowing both inner and outer layers to reach their respective blow-moulding temperatures substantially simultaneously.
Patent NZ-581613-A (NZ)
Title: Aluminium composite weatherboard routing and bending
Inventor: AL-TIAY WALID
IPC: E04C2/292
Filed: 2009-12-03
Abstract: Weatherboards are installed on site from aluminium composite material sheet that has been cut from a flat or curved sheet and grooved in accordance with a predetermined folding line pattern, then folded into the final profile by hand along the grooved folding lines as it is installed on the building. Folding during installation permits the hiding of the fasteners beneath the profile facing.
Patent NZ-582580-A (NZ)
Title: Controlling the relative phase of a pickup on a secondary side with respect to a converter on a primary side
Inventor: MADAWALA UDAYA KUMARA
IPC: H01F27/00
Filed: 2009-12-21
Abstract: Disclosed is a method provided which enables the control of contactless power transfer in an inductive power transfer system using a phase control technique. The method comprises adjusting the phase angle of a secondary-side pickup converter output voltage with respect to that of a primary-side converter. This controls the transfer of power between a primary conductive path and a load associated with the pickup. (62) Divided Out of 573241
Patent NZ-582768-A (NZ)
Title: Hygienic self sealing trap with one way valve comprising two substantially flat abutting surfaces of elastomeric material
Inventor: BOWDEN MAXTON JAMES
IPC: E03C1/12
Filed: 2010-07-02
Abstract: A method for installing a wastewater drain, by mounting and securing a flexible elastomeric body that acts as a one-way valve, shaped with an outer flange and shaped to transition from circular to end in two parallel flexible resilient flaps mounted within a tube that attaches or connects using engaging screw threads to the drain entrance.
Patent NZ-583047-A (NZ)
Title: A lipid aceltransferase and compositions comprising said protein for use as a food or feed enzyme
Inventor: SOE JORN BORCH
IPC: A21D8/04
Filed: 2008-02-27
Abstract: Disclosed is a lipid acyltransferase wherein the lipid acyltransferase comprises the amino acid sequence shown as SEQ ID NO: 90, or an amino acid sequence which has 95% or more identity with SEQ ID NO: 90.
Patent NZ-590755-A (NZ)
Title: Insecticidal compounds
Inventor: PITTERNA THOMAS
IPC: A01N43/80
Filed: 2009-07-24
Abstract: Disclosed is a compound of formula (I) or a compound of formula (I') e.g. 4-[5-(3,5-dichloro-phenyl)-4-hydroxy-S-trifluoromethyl-4,5-dihydro-isoxazol-3-yl-2-methyl-benzoic acid tert-butyl ester, wherein the variables are defined in the specification for combating and controlling insects, acarines, nematodes or molluscs.
Patent NZ-608376-A (NZ)
Title: Pyrazine derivatives as enac blockers
Inventor: BHALAY GURDIP
IPC: C07D487/10
Filed: 2011-09-16
Abstract: Provided are pyrazine derivative compounds,of Formula (I), wherein the variables are as described in the specification. Examples of the compounds include 3-(3-{ 2-[(E)-3,5-Diamino-6-chloro-pyrazine-2-carbonylimino]-1 ,3,8-triazaspiro[4.5]decane-8-carbonyl} -benzenesulfonylamino)-propionic acid dipropylcarbamoylmethyl ester and 1-[(3-{ 2-[(E)-3,5-Diamino-6-chloro-pyrazine-2-carbonylimine ]-1,3,8-triazaspiro[4.5]decane-8-carbonyl} -benzenesulfonylamino)-methyl]-cyclobutanecarboxylic acid 2-oxo-2-(2-trifluoromethyl-pyrrolidin-1-yl)-ethyl ester. The compounds are blockers of the epithelial sodium channel (ENaC). The compounds are useful in the treatment of respiratory diseases.
Patent NZ-614973-A (NZ)
Title: S1p modulating agents
Inventor: THOMAS JERMAINE
IPC: A01N43/40
Filed: 2012-02-03
Abstract: NZ 614973 The disclosure relates to derivatives of naphthalene, quinoline and quinazoline represented by structural formula (I), wherein the variables are as defined in the specification. These compounds are sphingosine 1-phosphate (S1P) modulators and are suitable for treating or preventing multiple sclerosis, an autoimmune disease, a chronic inflammatory disorder, asthma, an inflammatory neuropathy, arthritis, transplantation rejection, Crohn’s disease, ulcerative colitis, lupus erythematosis, psoriasis, an ischemia-reperfusion injury, a solid tumor, a tumor metastasis, a disease associated with angiogenesis, a vascular disease, a pain condition, an acute viral disease, an inflammatory bowel condition, insulin-dependent diabetes, or non-insulin dependent diabetes.
Patent NZ-621318-A (NZ)
Title: Microorganisms and methods for producing 1,3-butanediol and related alcohols
Inventor: OSTERHOUT ROBIN E
IPC: C12P7/18
Filed: 2012-08-17
Abstract: The disclosure provides non-naturally occurring microbial organisms containing a 1,3-butanediol pathways comprising at least one exogenous nucleic acid encoding 1,3-butanediol pathway enzymes expressed in a sufficient amount to produce 1,3-butanediol. The disclosure additionally provides methods of using such microbial organisms to produce 1,3-butanediol by culturing a non-naturally occurring microbial organism containing a 1,3-butanediol pathway as described herein under conditions and for a sufficient period of time to produce 1,3-butanediol.
Patent NZ-625114-A (NZ)
Title: Pyrazine kinase inhibitors
Inventor: PANDEY ANJALI
IPC: C07D241/28
Filed: 2012-11-23
Abstract: Provided are pyrazine compounds for inhibiting of Syk kinase, intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibition Syk kinase activity, and methods for treating conditions mediated at least in part by Syk kinase activity.
Patent NZ-629816-A (NZ)
Title: Therapeutic peptides
Inventor: WUCHERPFENNIG KAI W
IPC: C07K16/00
Filed: 2014-03-14
Abstract: Discloses compositions comprising antibodies and T-cell receptors (CARs) against MHC class I polypeptide related sequence A (MICA) with defined heavy chain variable regions which bind defined epitopes. Discloses that the antibodies/compositions may be used in the treatment of cancer. Binding of the antibodies prevenets MICA mediated down regulation of the NKG2D receptor and increases specific lysis of target cells by NK cells.
Patent NZ-708589-A (NZ)
Title: Granular fertilizers having improved dust control
Inventor: PEACOCK LAWRENCE ALAN
IPC: C05G5/00
Filed: 2013-11-18
Abstract: An oil-based coating for fertilizer granules impregnated with a polymer additive and related methods of applying the oil-based coating. The polymer additive can comprise homopolymers, copolymers, or combinations thereof, including polyethylene homopolymers. The polymer additive increases the viscosity of the oil-based coating, thereby increasing the duration for which the coating is capable of controlling or inhibiting the formation of dust particulates from the fertilizer granules.