baber/WOPTO huggingface dataset:
Patent EA-001385-B1 (EA)
Title: Intermediate for use in docetaxel synthesis and production method therefor
Inventor: SISTI NICHOLAS J
IPC: C07D305/14
Filed: 1997-02-27
Abstract: 1. A chemical compound having the formula   2. A method of producing a compound having the formula   comprising the step of acylating 10-deacetyl Baccatin III with at least a 1.5 equivalents of n-butyl lithium and at least 1.5 equivalents of benzyl chloroformate in tetrahydrofuran. 3. A method according to claim 2 wherein the 10-deacetyl Baccatin III is first dissolved in said tetrahydrofuran to form a solution after which said n-butyl lithium is next added to form a first mixture and thereafter said benzyl chloroformate is added to said first mixture to form a second mixture. 4. A method according to claim 3 wherein said n-butyl lithium is in a hexane solution, said n-butyl lithium in hexane being added dropwise to said solution. 5. A method according to claim 3 wherein said solution is cooled to a reduced temperature of -20 degree C. or less prior to adding said n-butyl lithium. 6. A method according to claim 5 wherein the reduced temperature is about -78 degree C. 7. A method according to claim 5 wherein said first mixture is stirred at the reduced temperature for about five minutes and wherein said second mixture is stirred at the reduced temperature for about one hour. 8. A method according to claim 7 wherein said second mixture is quenched with ammonium chloride and thereafter reduced to a residue. 9. A method according to claim 8 including the step of dissolving said residue in organic solvent not misible in water to form a residue solution after which said residue solution is first washed with water and next washed with brine to form an organic layer. 10. A method according to claim 9 including the steps of removing, drying and recrystallizing said organic layer. 11. A method according to claim 10 wherein recrystalization is accomplished with ethyl acetate/hexane. 12. A method according to claim 2 wherein the step of acylating said 10-deacetyl Baccatin III is accomplished with at least two equivalents of n-butyl lithium and at least two equivalents of benzyl chloroformate.
Patent EA-003052-B1 (EA)
Title: Antiarrythmic drug
Inventor: TSVETKOV PLAMEN KURBATOV
IPC: A61K31/343
Filed: 2000-07-21
Abstract: 1. An antiarrhythmic drug containing (2-bytil-3-benzofuranil)[4-[2-(dyethylamino)ethoxy]-3,5-diiodophenyl]methanone (amiodarone) hydrochloride and auxiliaries with a 2,3: 1 ratio between amiodarone hydrochloride and maize starch with sodium starch glycolate, whereby the drug comprises: amiodarone hydrochloride	between 100 and 300 mg, maize starch	between 40 and 90 mg, sodium starch glycolate	between 10 and 30 mg, collidone VA 64 (vinylpyrrolidone with vinylacetate copolymer)	between 6 and 18 mg, mannitol	between 15 and 35 mg, colloid silicon dioxide	between 0.5 and 35 mg, talc	between 6 and 15 mg, magnesium stearate	between 1 and 5 mg.
Patent EA-003981-B1 (EA)
Title: Device for the extraction of a substance having a moveable component
Inventor: KOLLEP ALEXANDRE
IPC: A47J19/00
Filed: 2001-04-10
Abstract: 1. A device for the extraction of a substance for the preparation of a beverage, comprising a fixed first component, a second component moveable (2) relative to the first along an axis of rotation (3) arranged at the rear of said two components, the front of each component forming a housing (5) for the substance to be extracted, and means for closing and opening the two components, said means being integral with the fixed part and with the moveable part, characterized in that said device comprising, furthermore, a control (15) and a valve (14) associated with said control, which are placed on the upper part of the moveable second component (2), in such a way that said control (15) and said valve (14) are near to the housing (5) for the substance to be extracted. 2. The device of claim 1, wherein the control and the valve associated with said control adapted to take a neutral position in which beverage is prepared and the position in which steam is formed. 3. The device of any one of claims 1 or 2, wherein the valve is a ceramic valve.
Patent EA-006552-B1 (EA)
Title: Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5ht-2 receptor
Inventor: NILSSON BJORN M
IPC: A61P/
Filed: 2001-11-20
Abstract: A compound of the general formula (I), wherein R1, R2, X, Y and Z are as described in the specification.
Patent EA-007790-B1 (EA)
Title: Benzo(a)pirano(3,2-h)acridin-7-one compounds and pharmaceutical composition containing the same
Inventor: KOCH MICHEL
IPC: A61P35/00
Filed: 2004-06-24
Abstract: A compound of formula (I):wherein X and Y are a group selected from hydrogen, halogen, hydroxy, alkoxy, nitro, cyano, alkyl, trihaloalkyl and NRRwherein Rand Rare described in the detailed description;Ris hydrogen or alkyl;Ris selected from hydrogen, alkyl, -OR'', -NR'R', -O-T-OR', -NR'-T-NR'aR', -NR'-C(O)-TH, -O-C(O)-TH, -O-T-NR'R', -NR''-T-OR'', -NR''-T-COR''and -NR''-C(O)-T-NR'R'wherein R', R'', R'and Tare defined in the detailed description;Rand Rare hydrogen or alkyl; andA is -CH(R)-CH(R)-, -CH=C(R)-, -C(R)=CH-, -C(O)-CH(R) or -CH(R)-C(O) wherein R, R, Rand Rare defined in the detailed description,isomers thereof defined in the detailed description, N-oxide, addition salts thereof with a pharmaceutically acceptable acid or a base.Medicaments.
Patent EA-009825-B1 (EA)
Title: Gaming machine
Inventor: OKADA KAZUO
IPC: A63F13/10
Filed: 2005-12-26
Abstract: One embodiment of the present invention is a gaming machine connected to a network, and the gaming machine comprises: a detecting unit which detects a figure; a game-progressing information sending unit which sends to another device game-progressing information indicating that the gaming machine is in game-progressing based on the detection information detected by the detecting unit; a game-progressing information receiving unit which receives the game-progressing information sent from other device; and a display unit which displays an image indicating the another gaming machine being in a game-progressing mode, based on the received game-progressing information on the another gaming machine.
Patent EA-011353-B1 (EA)
Title: Method for clarification of cell samples for industrial scale production of therapeutic proteins
Inventor: THOMMES JORG
IPC: C12N1/02
Filed: 2005-06-21
Abstract: Methods for clarification of cell samples using centrifugation in combination with depth filtration.
Patent EA-014210-B1 (EA)
Title: Automatic gain control circuit, system including such circuit and method for automatic gain control
Inventor: BENHAMOUDA FRANCK
IPC: H03G7/08
Filed: 2006-10-25
Abstract: An automatic gain control circuit including a variable gain amplifier (11) adapted to receive a received signal (R) and to output an amplified signal (A) to an analog to digital converter (20), and a gain controller (12) which is connected to said variable gain amplifier (11) for receiving said amplified signal (A) and for controlling a gain of said variable gain amplifier (11). The gain controller (12) is adapted to determine an occurrence of a threshold event each time the amplified signal (A) has reached a predetermined threshold, decrease the gain of the variable gain amplifier (11) at each occurrence of a threshold event, measure a delay since the last threshold event, increase the gain of the variable gain amplifier (11) if the delay is greater than a delay specified value and if the gain of the variable gain amplifier (11) is not maximum.
Patent EA-019160-B1 (EA)
Title: Process for the preparation of sildenafil
Inventor: TIAN GUANGHUI
IPC: C07D487/04
Filed: 2007-12-21
Abstract: The present invention is directed to a process for the preparation of the compound of Formula (I), comprising the step of converting a compound selected from the group consisting of the compounds of formulae (II), (III) and (IV), wherein X is halogen, in one or more steps to give the compound of formula (I). The invention is also directed to a process for the preparation of a pharmaceutical composition comprising the compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof. Moreover, the invention relates to intermediates suitable for use in the above processes as well as processes for their preparation.
Patent EA-014845-B1 (EA)
Title: Gripper for objects
Inventor: MIZELMOE LEENDERT CORNELIS
IPC: B66C1/42
Filed: 2007-11-02
Abstract: The invention relates to a device for engaging objects, such as heat exchangers of varying sizes, which comprise a bundle of feed-through tubes extending between two end plates, said device comprising at least one gripper provided with: - at least a first and a second gripper arm, at least one of which is movable with respect to the other gripper arm for enclosing at least one object therebetween; ; and - a driving mechanism connected to at least one of said first and second gripper arms for closing or opening the gripper as needed, wherein at least one of said first and second gripper arms comprises a first gripper arm part and the second gripper on part, which first and second gripper arm parts are pivotally coupled together, and an adjusting mechanism provided between said first and second gripper arm parts, said adjusting mechanism being arranged for adjusting the angle between said gripper arm parts in dependence on the diameter of the object to be engaged prior to engaging said object.
Patent EA-020738-B1 (EA)
Title: Integrated unsupported slurry catalyst preconditioning process
Inventor: REYNOLDS BRUCE E
IPC: C10G47/00
Filed: 2007-12-05
Abstract: A process for slurry hydroprocessing, which involves preconditioning a slurry catalyst for activity improvement in vacuum residuum hydroprocessing units. Preconditioning the slurry catalyst raises its temperature, thereby reducing shock on the catalyst slurry as it enters the hydroprocessing reactor.
Patent EA-016000-B1 (EA)
Title: Method and apparatus for linking mobile communication devices to wireless networks in underground edifices
Inventor: HUNZIKER CHRISTOPH
IPC: H04W84/12
Filed: 2007-12-28
Abstract: Disclosed is an apparatus for linking mobile communication devices to wireless networks in underground edifices. Said apparatus comprises a plurality of base stations which are arranged at a spatial distance from one another inside tunnel systems (11, 12), substantially in the direction of the tunnel axes, such that the reception areas (16) of two adjacent base stations (21, 22, 23) overlap (25) as little as possible, all base stations (21, 22, 23) operating on a single common channel. In a method used for said apparatus, the mobile station switches to an adjacent base station when a quality signal drops below a predetermined threshold value.
Patent EA-016663-B1 (EA)
Title: Method and apparatus for coating pipes
Inventor: LEIDEN LEIF
IPC: B29C48/08
Filed: 2008-04-24
Abstract: Method and apparatus for coating a pipe (2) or a pipe section with a layer of at least one polymer. The method comprises providing a pipe (2) or a pipe section having an outer surface defining the periphery of the pipe or pipe section; applying on the outer surface of the pipe or pipe section a layer of at least one polymer material in melt stage using a nozzle (3), which is mounted on a carriage capable of travelling along the periphery of the pipe (2) or pipe section; and moving the carriage along at least a part of the periphery during the application of the polymer material to form a layer on the surface of the pipe (2) or pipe section. The present invention is particularly useful for coating field joints in pipelines.
Patent EA-021222-B1 (EA)
Title: Biologically active proteins having increased in vivo and/or in vitro stability
Inventor: SKERRA AME
IPC: C12P21/00
Filed: 2008-06-20
Abstract: The present invention relates to biologically active proteins comprising at least two domains wherein a first domain of said at least two domains comprises an amino acid sequence having and/or mediating said biological activity and a second domain of said at least two domains comprises an amino acid sequence consisting preferably of at least about 100 amino acid residues forming a random coil conformation whereby said random coil conformation mediates an increased in vivo and/or in vitro stability of said biologically active protein. Furthermore, nucleic acid molecules encoding the inventive biologically active proteins and vectors and cells comprising said nucleic acid molecules are disclosed. In addition, the present invention provides for compositions comprising the compounds of the invention as well as for specific uses of the biologically active proteins, nucleic acid molecules, vectors and cells of the invention.
Patent EA-019705-B1 (EA)
Title: Food composition exhibiting dietary and prophylactic properties (embodiments) and functional food products included thereinto, including beverages
Inventor: RODYUSHKOVA GALINA VASILIEVNA
IPC: A23L33/00
Filed: 2010-02-12
Abstract: The invention relates to food industry, providing three embodiments of food compositions having dietary and prophylactic properties including food polyol/combinations of food polyols, dry extract of rosehips, dietary fibers, and also sucralose and steviosid; or sucralose; or steviosid. The compositions are provided for being added to functional food products including beverages to increase their life time and preserve their organoleptic and textural properties.
Patent EA-015979-B1 (EA)
Title: Method for equipping vertical pit shaft with hoisting units
Inventor: SMYCHNIK ANATOLIJ DANILOVICH
IPC: E21D7/00
Filed: 2009-12-03
Abstract: The invention relates to mining industry and may be used to equip vertical shafts with high-powered hoisting units. The method includes equipment of shaft with large-sized and auxiliary hoisting units with a combined cable and cantilever armour. The skip shaft is designed to be an intake one, an air flow is directed towards a loaded skip. Two large-sized skips on rope guides, driven by a multiple-rope hoist, and a small-sized cage of emergency and maintenance one-ended hoist with a rigid cantilever armour are placed in the skip. The cage shaft is designed to be an air exhaust one, a large-sized cage on rope guides, driven by a multiple-rope hoist, a small-sized cage of one-ended hoist and integral counterweights with a rigid cantilever armour are placed therein. The large-sized hoisting units in both shafts are equipped in such a way that their direct axis coincides with the direction of ventilating current movement in air ducts and producing level underground openings adjacent to the shafts and symmetrically located on both sides of shafts. Rubber ropes having the length equal to at least total length of large-sized hoisting units are installed in the skip shaft on the side of lining, in the place where the hoisting units meet. The large-sized hoisting units are equipped with aerodynamic planes in the upper end part on the side of internal clearance between them. The planes are set at an angle to the horizontal. The proposed method allows to increase efficiency and safety of hoisting during underground mining.
Patent EA-017147-B1 (EA)
Title: Method of producing tertiary amyl ethyl ether
Inventor: BOYER CHRISTOPHER C
IPC: C07C41/05
Filed: 2008-08-25
Abstract: A process for the production of tertiary ethers, including: feeding a hydrocarbon stream comprising isoolefins and propionitrile to a distillation column reactor system containing at least one etherification reaction zone; feeding a Cto Cmonoalcohol or mixture thereof to the distillation column reactor; concurrently in the distillation column reactor system: reacting a portion of the isoolefins with a portion of the alcohols to form a tertiary ether; and separating the tertiary ether from unreacted isoolefins; withdrawing the tertiary ether and propionitrile from the distillation column reactor system as a bottoms; withdrawing the unreacted isoolefins from the distillation column reactor system as an overheads; and operating the distillation column reactor system such that the etherification reaction zone is substantially free of propionitrile.
Patent EA-018888-B1 (EA)
Title: Process and installation for surface preparation by dielectric barrier discharge
Inventor: TIXHON ERIC
IPC: B08B7/00
Filed: 2009-07-16
Abstract: A process for surface preparation of a substrate (2), which comprises introducing or running a substrate (2) into a reaction chamber (6, 106). A dielectric barrier (14, 114) is placed between electrodes (1, 10, 110). A high-frequency electrical voltage is generated, to generate filamentary plasma (12, 112). Molecules (8, 108) are introduced into the reaction chamber (6, 106). Upon contact with the plasma, they generate active species typical of reacting with the surface of the substrate. An adjustable inductor (L) placed in parallel with the inductor of the installation is employed to reduce the phase shift between the voltage and the current generated and to increase the time during which the current flows in the plasma (12, 112).
Patent EA-021710-B1 (EA)
Title: Ultrasonic web joining device
Inventor: YAMAMOTO HIROKI
IPC: B29C65/08
Filed: 2010-07-30
Abstract: An anvil 200 has a temperature adjustment mechanism 262 including a heater. The anvil 200 has a heat transmitter 261 transmitting heat generated by the temperature adjustment mechanism 262. The anvil 200 has a temperature sensor 270 detecting a temperature of an anvil attachment portion 112a in which the anvil 200 of a rotating drum 110 is installed. The ultrasonic joining device 100 includes a controller configured to control a temperature to which the rotating drum 110 should be heated by the temperature adjustment mechanism 262. The controller controls a heat generation amount of the temperature adjustment mechanism 262 on the basis of the result of detection by the temperature sensor 270. The temperature adjustment mechanism 262 and the heat transmitter 261 are installed in each of the multiple anvils 200.
Patent EA-025919-B1 (EA)
Title: Systems and methods for modeling 3d geological structures
Inventor: MAUCEC MARKO
IPC: G01V1/28
Filed: 2011-01-07
Abstract: Systems and methods for modeling a three-dimensional (3D) geological structure to improve maximum continuity interpolation. The integration method describes local anisotropic effects and introduces interpolation techniques to perform the interpolation between two points of interest along a direction of maximum continuity and across fault surfaces.
Patent EA-018435-B1 (EA)
Title: Method for manufacturing heterostructures (embodiments) for mid-ir range, heterostructure (embodiments) and led and photodiode based on this heterostructure
Inventor: KIZHAEV SERGEY SERGEEVICH
IPC: H01L21/205
Filed: 2012-09-14
Abstract: The invention relates to manufacturing techniques for spontaneous emission sources based on semiconductor compounds of type ABfor a spectral range of 2.6-4.7 microns and to manufacturing techniques for photosensitive structures for a spectral range of 2.0-4.7 microns. According the first embodiment, the heterostructure comprises a substrate comprising InAs, a barrier layer comprising InSbP and disposed on the substrate, an active layer comprising InAsSbP and disposed on the barrier layer. LEDs based on the heterostructure according to the first embodiment emit at a wavelength range of 2.6-3.1 microns. According to the second embodiment, the heterostructure comprises a substrate comprising InAs, an active area comprising InAsSb and disposed on the substrate, a barrier layer comprising InSbP and disposed on the active area. The active area may comprise a bulk active layer InAsSb, quantum wells of InAs/InAsSb strained superlattice or GaInAs/InAsSb. LEDs based on the heterostructure according to the second embodiment emit at a wavelength range of 3.1-4.7 microns, while the photodiodes provide a broadband sensitivity in the range of 2.0-4.7 microns. According to the method for manufacturing the heterostructure, tret-butilarsin is used as a source of arsenic and tret-butylphosphine is used as a source of phosphorus.
Patent EA-024367-B1 (EA)
Title: Process and apparatus for enhancing recovery of hydrocarbons from wells
Inventor: NIKIPELO HAROLD J
IPC: E21B43/25
Filed: 2010-09-07
Abstract: A method of enhancing recovery of hydrocarbons from a hydrocarbon formation includes heating the hydrocarbon formation by injecting heated gas into a borehole; generating a series of pressure pulses in the borehole by flashing a liquid into a gas; and directing the pressure pulses into the hydrocarbon formation.
Patent EA-024944-B1 (EA)
Title: Hydrogen unit for utilisation of energy of renewable sources with seasonal and cyclic mode of energy consumption
Inventor: KHABARDIN VASILY NIKOLAEVICH
IPC: H02J15/00
Filed: 2012-12-26
Abstract: The invention relates to power engineering, in particular to device for utilisation of energy of renewable sources in the form of electricity, heat and fuel. It can be used for power supply of facilities mainly with season and cyclic mode of power consumption, which include individual residential buildings and office buildings, small industrial enterprises and farm enterprises, horticultural partnerships and small rural settlements. The hydrogen-based multifunctional electric power plant is disclosed which is adapted to the season and cyclic mode of power consumption. It comprises a converter of renewable energy to electric energy, a water electrolyser, a hydrogen accumulator, and fuel elements. The plant provides accumulation of energy of the renewable sources in hydrogen during idle period of power consumption with further conversion of this energy to the electric power, heat and fuel. It is ecologically safe. The plant provides utilisation of energy of renewable sources in full scope, without transients, and at relatively uniform load during the year, while increasing efficiency of utilisation of the renewable sources and the plant during season and cyclic mode of power consumption. Due to absence of movable parts the operation expenses are low, and the plant can be used with periodic and variable energy sources, such as wind and sun.
Patent EA-026492-B1 (EA)
Title: Segment for a rehabilitation pipe, and pipe rehabilitation method
Inventor: KAMIYAMA TAKAO
IPC: F16L55/165
Filed: 2013-10-03
Abstract: The present invention relates to a segment for a rehabilitation pipe and to a pipe rehabilitation method using such segments. A segment for a rehabilitation pipe comprises an inner surface plate constituting an inner circumferential surface, and side plates and end plates provided upright on a peripheral edge of the inner surface plate. The inner surface plates, side plates and end plates are formed integrally from a plastic material, and the segments are linked in a circumferential direction and in a pipe-length direction to install a segmental rehabilitation pipe inside an existing pipe. Each side plate is provided, in the vicinity of the end plate, with an opening used for the process of linking the segments in the circumferential direction. It is possible to insert a linking member through the opening and to link easily the segments in the circumferential direction. The opening formed in the side plate enables filler material injected into the space between the existing pipe and the segmental rehabilitation pipe to flow in or out through the opening. This makes it possible to link the segments in the circumferential direction in an easier way, and to reduce total labour intensity necessary in the rehabilitation process.
Patent EA-030343-B1 (EA)
Title: Terminal, base station, communication system and communication method
Inventor: NOGAMI TOSHIZO
IPC: H04W72/04
Filed: 2012-07-19
Abstract: A terminal for communicating with a base station monitors a physical downlink control channel positioned in a physical downlink control channel region, and an enhanced physical downlink control channel positioned in a physical downlink shared channel region that differs from the physical downlink control channel region. When an enhanced physical downlink control channel is detected, the terminal reports response information via a physical uplink control channel resource corresponding to the resource in which the enhanced physical downlink control channel was detected.