baber/WOPTO huggingface dataset:
Patent PT-903348-E (PT)
Inventor: GERHARD HOFLE PROF DR
IPC: A61K31/00
Filed: 1996-11-18
Abstract: Epothilone derivatives of formula (I)-(III) are new. R = H or 1-4C alkyl; Y Z = H, halo, pseudohalogen, OH, 1-6C acyloxy, 1-6C alkoxy or benzoyloxy; or Y+Z = bond or O; (a) R' = Q; A = H; B = OR1; and R" = R2; or R"+B = C(O)O, C(S)O, S(O)O, Si(R")2O or C(R")(R"')O; (b) R' = C(=X)Me or CH(OX')Me; A = H; B = OR1; and R" = R2; (c) R' = Q; and A+B = bond; X = O, NOR4, N-NR4R5 or N-NHCONR4R5; X' = H, 1-18C alkyl, 1-18C acyl, benzyl, benzoyl or cinnamoyl; Q = a group of formula (i); and R1-R5 = H, 1-6C alkyl, 1-6C acyl, benzoyl, 1-4C trialkylsilyl, or benzyl or phenyl (both optionally substituted by 1-6C alkoxy, 6C alkyl, OH and halo); or R4+R5 = 2-6C alkylene. Epothilone A and B are excluded. Also claimed is the production of epothilone A or B and/or their 12,13-bis-epi derivatives comprising the epoxidation of epothilone C (for A or derivatives) or D (for B or derivatives) especially using dimethyldioxirane or a peracid.
Patent PT-933441-E (PT)
Inventor: HOLLRIGL GUNTHER
IPC: C22F1/043
Filed: 1998-01-29
Abstract: A die cast component of precipitation hardenable aluminum-magnesium-silicon alloy is subjected to a heterogenization anneal to increase its ductility. In the production of a component of Mg2Si precipitation hardenable aluminum alloy with a Si or Mg2Si eutectic by die casting, the die cast component is subjected to a heterogenization anneal at 320-410 degrees C for 320-10 min. Preferred Features: The aluminum alloy contains 2.0-11.0 wt.% Si and 0.10-5.5 wt.% Mg, with optional additions of 0.1-0.5 wt.% Fe and 0.2-1.2 wt.% Mn.
Patent PT-1042226-E (PT)
Inventor: MEIJER JOHANNES ALBERTUS MARIA
IPC: C01D7/35
Filed: 1998-12-22
Abstract: A process is presented in which anhydrous soda is crystallized and worked up to produce anhydrous soda crystals with a bulk density from 1300 to 1600 kg/m3. The process is characterized in that a solvent is used that allows the crystals to be formed and handled at atmospheric pressure in the presence of water without the monohydrate of soda being formed.
Patent PT-994035-E (PT)
Inventor: KORTE KLAUS
IPC: B65D1/22
Filed: 1999-09-14
Abstract: The moulded plastics cargo container has integral runners (5) which have a wider longitudinal section (15) on their outer upper faces. The container  base, adjacent to the edges, has upwardly sloped faces (17) above the runners. The angle of the floor adjacent to the edges matches the upper slope of the runners.
Patent PT-1087680-E (PT)
Inventor: KRUSELL MARCUS
IPC: B60R11/02
Filed: 1999-06-11
Abstract: An adapter system for tools, phones and cases and bags, in particular for mobile phone cases, whereby the adapter system comprises a connector for a multi purpose use, whereby the adapter system comprises 1) an adapter (4) comprising a first washer (4a) having a substantially U-shaped space (11) provided with a flange, and a locking snapping tongue (6, 7), which adapter (4) is arranged to be brought into operation with 2) a holder (9, 22) provided with a second washer (10, 23) arranged to be brought into operation with said flange provided space (11) in said first washer (4a).
Patent PT-1147061-E (PT)
Inventor: MORTIMER MARK DANIEL
IPC: B01F23/70
Filed: 1999-12-23
Abstract: A method of producing a rheologically stable concentrated aqueous suspension of a particulate alkaline earth metal carbonate which method comprises the following steps: (a) preparing a dilute aqueous suspension of the carbonate having a solids content of not more than 40% by weight; (b) dewatering the dilute aqueous suspension to form a carbonate suspension having a solids content in the range of from 45% to 65% by weight; (c) optionally mixing with the dewatered suspension formed in step (b) a dispersing agent for the carbonate to form a fluid suspension; (d) further dewatering the fluid suspension formed in step (b) by thermal evaporation under reduced pressure to raise the solids content of the suspension by a further differential amount of at least 5% by weight; and (e) after at least some of the dewatering in step (c) treating the suspension by a mechanical working process in which at least 1 kW.hr per tonne of carbonate on a dry weight basis is dissipated to refluidise the suspension.
Patent CA-2743603-F (CA)
Inventor: WIDEN BO
IPC: E05B27/10
Filed: 2010-01-04
Granted: 2010-08-26
Abstract: Une clé pour une utilisation dans une serrure à barillet avec un barillet de clé rotatif comportant une lame de clé allongée avec une partie inférieure relativement large et une partie supérieure relativement étroite. Une zone de transition en forme de gradin entre la partie inférieure plus large et la partie supérieure étroite. La lame de clé comprend une rainure de profil longitudinale située à côté de la zone de transition en forme de gradin qui s'étend le long d'au moins une partie de la longueur de la lame. Une paroi intérieure de la rainure est sensiblement parallèle à une surface latérale de la partie inférieure de la lame de clé. La rainure de profil longitudinale comprend une partie en contre-dépouille adjacente à une partie d'arête de la lame de clé et à l'intérieur de celle-ci. L'extérieur de la partie d'arête forme une partie de la surface latérale de la lame dans la partie inférieure relativement large jusqu'à la zone de transition en forme de gradin et l'intérieur de la partie d'arête faisant face à la paroi intérieure de la rainure.
Patent IE-38763-L (IE)
Title: Nitrile-substituted thionothiolphosphoric acid esters
IPC: A01N57/10
Filed: 1974-01-17
Abstract: O-ethyl-S-n-propyl-O-vinyl-thionothiolphosphoric acid esters of the formula IN WHICH R is lower alkyl, carbo-lower alkoxy, or phenyl or naphthyl optionally substituted by halogen, nitro, nitrile, lower alkyl, lower alkoxy or halo-lower alkyl and R' is hydrogen or lower alkyl, WHICH POSSESS INSECTICIDAL AND ACARICIDAL PROPERTIES.
[US3892823A]
Patent IE-37541-L (IE)
Title: Converting a steroid to a crystalline solvate
IPC: C07J5/00
Filed: 1973-04-18
Abstract: 1429184 Anti-inflammatory steroid crystallisates ALLEN & HANBURYS Ltd 18 April 1973 [20 April 1972] 18421/72 Heading C2U [Also in Division C4] The invention comprises an anti-inflammatory steroid in the form of a crystalline solvate with a halobydrocarbon or such a crystalline material from which part or all of the halohydrocarbon has been removed, the particle size of substantially all of the steroid material being such as to permit inhalation into the human bronchial system when dispersed as an aerosol, e.g. 2- 20 Á. Several specific steroids of the pregna-1,4- diene-3,20-dione series are mentioned. Specified halohydrocarbons are CH 2 Cl 2 , CHCl 3 , CFCl 3 , CCl 2 F 2 , C 2 Cl 2 F 4 , C 2 Cl 3 F 3 and C 2 ClF 5 . Preparation.-The initial unsolvated steroid is first contacted with the halohydrocarbon. Simple suspension with concurrent comminution yields an inventive product. Alternatively the halohydrocarbon is mixed with a solution of the steroid in a conventional steroid solvent (e.g. MeOH, EtOH, Pr<SP>i</SP>OH, HCHO, CH 2 Cl 2 , acetone) and the resulting mixture is either crystallized at low temperature, e.g. -29‹ to -40‹ C., or distilled until the conventional solvent has been removed whereupon the solvate crystallizes. The optional removal of the halohydrocarbon from the solvate may be effected by heating at up to 60‹ C. in a vacuum, and may also take place automatically upon comminution. The latter may be effected ultrasonically or in a ball or fluid energy mill. Anti-inflammatory aerosol compositions comprise a suspension of a product of the invention in an aerosol propellant and a dispersing agent. (The steroid has a modified crystal structure and does not exhibit crystal growth in the propellant.)
[GB1429184A]
Patent IE-32112-L (IE)
Title: Measuring a continuous length of material
IPC: B65H61/00
Filed: 1968-06-10
Abstract: 1,162,966. Selective signalling. SIEMENS A.G. 7 June, 1968 [12 Aug., 1967], No. 27327/68. Heading G4H. The length of thread 1 fed by a pulley 2 is measured by shaping and integrating 4 pulses from a Hall plate co-operating with a magnet 3 rotated by the pulley, so as to produce a D.C. potential corresponding to the speed of the pulley, which potential is applied to a variable speed motor 5 which drives a counting mechanism 6. The counter can be preset to a required length and used to control 7, stopping of thread feed when the required length has been fed.
[GB1162966A]
Patent IE-35611-L (IE)
Title: Tyres, internal lubricants
IPC: B60C13/00
Filed: 1971-06-11
Abstract: 1359468 Lubricating contacting interior surfaces of a tyre on deflation DUNLOP HOLDINGS Ltd 9 June 1971 [20 June 1970] 30034/70 Heading B7C A pneumatic tyre 1, which, when mounted on the wheel rim 2 for which it is designed and inflated, has an aspect ratio of between 30 and 75% and a tread whose width is greater than the distance between the tyre bead heels, comprises a coating of a lubricating material disposed on at least a part of the interior surface of the tyre to lubricate those parts of the tyre interior surface which contact when the tyre deflates under load, thereby to prevent tyre destruction due to frictionally generated heat and facilitate running of the tyre in the deflated state. The coating may be such as to withstand temperatures of at least 145‹ C. without deterioration of either the coating or its lubricating properties. The coating may be formed by incorporating a liquid, e.g. castor oil, which is insoluble in rubber, in a rubber liner 3 of the tyre, the liquid migrating to the exposed surface of the liner to form the coating thereon, there being a barrier layer 4 impermeable to the liquid between the liner 3 and the tyre carcass. Alternatively the coating may be particles of solid P.T.F.E., or a gel, applied directly to the interior surface of the tyre. The coating may, as shown in Fig. 1, be applied to portions A, D of the interior surface adjacent the beads and to portions B, C adjacent the tread edges, or may alternatively be provided over the whole of the interior surface. The thickness of the coating may be in the range 0À001-0À025 inch. The tyre may be a radial-ply tyre with a breaker assembly, or may be a cross-ply tyre. The wheel rim 2 which the tyre is intended to be used with has means to prevent the tyre from being dislodged from the rim when running deflated, which means may comprise a flat base on the rim, i.e. such that the rim is without a well into which the tyre beads can fall, as shown in Fig. 1, and/or a bead spacer ring or removable studs on the rim. The flat base rim may be divisible to permit tyre mounting and demounting, or may be a rim initially formed with a well which is closed up after the tyre has been mounted on the rim. Specifications 1,359,461, 1,359,463, 1,359,464 and 1,359,465 are referred to.
[GB1359468A]
Patent IE-870815-L (IE)
Title: Liquid detergents
IPC: C11D1/83
Filed: 1987-03-30
Abstract: Liquid detergent compositions containing anionic synthetic surfactant, C12-C14 alkyl or alkenyl succinate builder and C12-C14 fatty acid, in a molar ratio of succinate to fatty acid of from about 0.8 to about 2.4, provide a minimum of suds in otherwise high sudsing compositions.
Patent IE-35445-L (IE)
Title: Pressurized container.
IPC: A61K9/12
Filed: 1971-07-07
Abstract: 1367075 Foam generation WILKINSON SWORD Ltd 6 July 1971 [18 July 1970] 34944/70 Heading BiC [Also in Divisions A5 C4 and Fl] A foam containing hypochlorite ions is created by dispensing from a pressurised container a soap solution and a source of hypochlorite ions held in separate compartments in the container, the contents of which are mixed as they are dispensed upon operation of a valve in the proportions of 3 to 10 volumes of soap solution to 1 volume of the hypochlorite ion source. The soap solution contains stearic acid with lauric acid and/or myristic acid and potassium and/or lithium hydroxide. In addition the solution may contain sodium and/or lithium lauryl sulphate, sodium carboxymethyl cellulose, and a long chain tertiary amine-N-oxide to improve the foam. An aqueous solution of lithium hypochlorite which may also contain potassium and/or lithium chloride and hydroxide may be used as the hypochlorite ion source. Alternatives include other alkali metal hypochlorites, non-metallic inorganic acids such as N-chlorosulphamic acid, and organic compounds which yield hypochlorite ions with water such as chlorimides N-chloro sulphonamides, and chlorinated hydantoins &c. The foam is used for treating burns, lesions, gangrene &c.
[GB1367075A]
Patent IE-830981-L (IE)
Title: Producing uniform fibrous web structural assembly for a curtain wall
IPC: D04H1/72
Filed: 1983-04-28
Abstract: A method and apparatus is disclosed for producing high quality fibrous webs at high rates of speed. Fibers are fed to a rotating lickerin for opening, then to a rotating card cylinder for individualizing, and are then doffed into an air stream from which the fibers are condensed, as on a moving foraminous belt.
[US4475271A]
Patent IE-32265-L (IE)
Title: Multi-component toy.
IPC: A63H3/16
Filed: 1968-08-12
Abstract: 1,236,754. Toy animals. DART INDUSTRIES Inc. 9 Aug., 1968 [14 Aug., 1967], No. 38290/68. Heading A6S. A plurality of individual pieces may be arrayed in various arrangements on a master part which comprises a hollow break-apart box which may be used for storing the pieces and which is adapted so that the pieces may be attached to it. The break-apart box is eggshaped and divided so that it breaks apart on a line bisecting it longitudinally. The pieces may have cylindrical pins and the box corresponding cylindrical holes for attaching the pieces to box. The pieces may form sets, each set forming with the box a particular animal; a lion, a bear and a dog are exemplified. The holes in the box may have different sizes so that only certain members of each set of pieces may be inserted in a particular hole.
[GB1236754A]
Patent FI-823165-L (FI)
Inventor: BARTH WAYNE MONTICELLO
IPC: C07D499/00
Filed: 1982-09-13
Abstract: Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl-(5R)penam-3-alpha-carboxylic acid 1,1-dioxides and esters thereof, wherein the 2-beta-substituent is cyano, acetyl, alkoxycarbonyl, omegahydroxyalkoxycarbonyl, carbalkoxymethoxycarbonyl or dialkylaminocarbonyl; intermediates therefor wherein the 2-beta-substituent is carboxy, chlorocarbonyl or aminocarbonyl; methods for their preparation and use as beta-lactamase inhibitors.
Patent FI-831306-L (FI)
Inventor: KELLER HANS
IPC: F16L47/02
Filed: 1983-04-19
Abstract: A welding sleeve for connecting pipes formed of thermoplastic material includes an electrical conductor in the form of an electrical resistance wire. The resistance wire extends around the sleeve and has a pair of opposite ends for conveying current through the wire. The opposite ends of the wires can be connected directly to a source of electrical current, for instance a 220 DEG  V DIFFERENCE line. It is not necessary to provide transformers or timing relays. A melting material is incorporated into the conductor between its ends and it melts through when the energy necessary for welding the sleeve has been developed. After the current is supplied through the resistance wire, the welding process is completed when the predetermined melting material melts through. Such sleeves can be manufactured in a mass production operation, and the sleeves are much safer than the conventional devices used to-date.
Patent IE-801503-L (IE)
Title: Preparation of thienamycin.
IPC: C07D205/08
Filed: 1980-07-21
Abstract: In a process for the total synthesis of thienamycin from L-aspartic acid via intermediate III: <CHEM> R = H, blocking group or salt cation there is disclosed a process for preparing III via <CHEM> wherein R is a protecting group.
Patent IE-34790-L (IE)
Title: Digoxin monomethyl ethers.
IPC: C07D/
Filed: 1970-12-04
Abstract: 1,274,779. Digoxin ethers. BOEHRINGER MANNHEIM G.m.b.H. 3 Dec., 1970 [5 Dec., 1969], No. 57485/70. Heading C2U. The preparation of 3<SP>111</SP>- and 4<SP>111</SP>-O-methyldigoxin by reacting digoxin with dimethyl sulphate in dimethylformamide in the presence of barium hydroxide, is effected selectively by the additional presence of (a) aluminium oxide and an inert organic solvent or (b) aluminium isopropylate. The reaction mixture is then diluted with chloroform, and, after the addition of pyridine, evaporated in vacuo. The residue is separated, e.g. by multiplicative partition, into unreacted digoxin, which may be recycled, and (a) 4<SP>111</SP>-O-methyl-digoxin or (b) 3<SP>111</SP>-O-methyldigoxin respectively.
[GB1274779A]
Patent IE-34826-L (IE)
Title: Neriifolin derivatives.
IPC: C07C/
Filed: 1970-12-18
Abstract: 1,272,340. Neriifolin derivatives. BOEHRINGER MANNHEIM G.m.b.H. 17 Dec., 1970 [19 Dec., 1969], No. 60001/70. Heading C2U. The invention comprises compounds of formula (wherein one of R 1 and R 2 is C 1-3 alkyl or C 2-3 alkoxyalkyl and the other is H or C 1-3 acyl), and their preparation from neriifolin by alkylation followed, when required, by acylation. The inventive compounds are said to be cardioactive, and may be made up with carriers into pharmaceutical compositions for oral administration.
[GB1272340A]
Patent IE-831676-L (IE)
Title: Aphidicolane derivatives
IPC: C07C229/02
Filed: 1983-07-18
Abstract: Aphidicolane derivatives of the formula:  <IMAGE>  wherein R1 stands for hydrogen or a hydroxy radical, R2 stands for a hydroxy or methyl radical, or the group CR1R2 stands for a keto group; R3 stands for a formyl or hydroxymethyl radical, or for the group -CH2O.CO.OR6, wherein R6 stands for a defined radical or R2 and R3 are joined together to form the group -O.CO.OCH2-; R4 stands for a hydroxy radical; R5 stands for a formyl radical, a hydroxyalkyl radical -(CH2)1-3OH, a radical -CHR7OH, wherein R7 stands for a defined radical, or R5 stands for an azidomethyl or pyrrolidinylcarbonyloxymethyl radical, or for the group -CH2O.CO.OR8, wherein R8 stands for a defined radical, or R5 stands for the group -CH2O.CO.(CH2)m.CR11R12.(CH2)n.NR9R10, wherein m, n, R9, R10, R11 and R12 have defined values, or R5 stands for the group -CH2O.SO2.R13, wherein R13 stands for a defined radical; or R4 and R5 are joined together to form the group -O.CH2- or -O.CO.OCH2-; and, where appropriate, pharmaceutically-acceptable salts thereof. Processes for the preparation of said aphidicolane derivatives. Pharmaceutical compositions comprising one of the compounds and a pharmaceutical diluent or carrier. The compounds exhibit inhibitory activity against DNA-containing viruses and they inhibit the growth of some tumors.
Patent IE-801884-L (IE)
Title: Preparation of 1ó-hydroxyvitamin d compounds from¹1ó-hydroxy-3,5-cyclovitamin d compounds
IPC: C07C401/00
Filed: 1980-09-09
Abstract: A method for preparing 1 alpha -hydroxyvitamin D compounds from 1 alpha -hydroxy-3,5-cyclovitamin D compounds which comprises solvolyzing the 3,5-cyclovitamin D compound, exposing the solvolysis reaction products to actinic radiation in the presence of a photosensitizing agent and recovering the 1 alpha -hydroxylated vitamin D compounds. 1 alpha -hydroxylation is recognized as being essential to impart biological activity to vitamin D compounds and their derivatives. The present invention provides an efficient method for maximizing the yield of 1 alpha -hydroxylated vitamin D compounds.
[US4234495A]
Patent IE-851931-L (IE)
Title: 3-amino-1-hydroxypropane-1,1-diphosphonate crystal
IPC: C07F9/38
Filed: 1985-08-02
Abstract: The invention relates to a novel crystal modification, containing water of crystallization, of disodium 3-amino-1-hydroxypropane-1,1-diphosphonate of the formula <IMAGE> and to a process for the manufacture thereof. This modification is suitable for the oral treatment of disorders of the calcium and phosphate metabolism and associated diseases in warm-blooded animals.
[US4639338A]
Patent IE-41670-L (IE)
Title: Diisocyanato-diketenes.
IPC: C08G18/81
Filed: 1975-09-04
Abstract: The instant invention relates to novel diisocyanato-diketenes, i.e., compounds which contain the isocyanate and diketene groups of the beta -lactone type in one molecule, and to a process for the production thereof.
[US4009152A]
Patent IE-822005-L (IE)
Title: Milking inflation
IPC: A01J5/08
Filed: 1982-04-19
Abstract: A milking inflation or liner of the soft tubular rubber kind arranged for fitment in a rigid tubular teat cup shell to which pulsating air/vacuum is applied, the invention comprising the provision at the head or mouth end part of the inflation of a flexible resilient teat engaging collar having an inner annular part defining the inflation mouth in the form of a depending flange shaped to provide an inner inverted frusto-conical face at least part of which constitutes a main vacuum seal when engaged about an animal's teat, the upper inner portion of the collar from which the flange depends being inclined upwardly from the outer part of the collar and the junction of said frusto-conical face and inclined upper part being shaped to define a supplementary unbroken annular seal spaced from the frusto-conical face to be capable of engaging and sealing on the animal's teat during flexing of the collar in milking operations.
[US4457262A]
Patent IE-38754-L (IE)
Title: Manufacture of collapsible tubes
IPC: B29C65/00
Filed: 1973-11-09
Abstract: 1436538 Stamping JOHN DALE Ltd 9 Nov 1973 [17 Nov 1972 20 Feb 1973] 53264/72 and 8359/73 Heading B3Q Articles such as closures, bottle caps and collapsible tubes 60 are expanded in a chamber 52 by the products of a combustion occurring in a separate combustion chamber 11. The chamber 52 is connected by a valve chest 27 to the combustion chamber 11. A mixture of air or oxygen and a fuel such as petrol, natural gas or coal gas is supplied through an inlet valve 21 to a perforated tube 18 coiled about a heater 17. A sparking plug &c. 24 ignites the charge and a spring-pressed valve 33 is lifted by the expanding gases which pass through passages 36, 45 into the workpiece. This is expanded away from a seal 44 past which the gases exhaust through ports 57. A quick-release connection secures the chest 27 to the chamber 52. The combustion is a flashover rather than explosion, with pressures as low as 200 p.s.i.
[GB1436538A]
Patent IE-832108-L (IE)
Title: Thieno-thiazine
IPC: C07D513/04
Filed: 1983-09-08
Abstract: 4-Hydroxy-2-methyl-3-(2-pyridylcarbamoyl)-6-trifluoromethyl-2H-thieno[ 2,3-e]-1,2-thiazine 1,1-dioxide of the formula <IMAGE> I and its pharmaceutically acceptable salts which possess valuable pharmacodynamic properties are described. More particularly, the compound and its salts display antiinflammatory, analgesic and antirheumatic activities and they are readily accessible by reacting a corresponding alkyl ester with 2-aminopyridine and, if desired, subsequent salt formation.
[US4544655A]
Patent IE-892285-L (IE)
Title: Use of polymeric compounds in treatment
IPC: A61K31/78
Filed: 1989-07-14
Abstract: The use of polyacrylates for the manufacture of a medicament for the treatment of inflammatory bowel disease. Preferably the polyacrylate is carbomer or its sodium salt and most preferably carbomer 934P or its sodium salt. The medicaments may be administered orally or rectally, as appropriate, according to the site of the disease.
Patent IE-46022-L (IE)
Title: Production of frozen granulates
IPC: A23L3/44
Filed: 1977-12-29
Abstract: The device has a cooling column (1) with supply devices for coolant flows (2) and product liquid flows (3) in the centre of the upper part of the cooling column (1) and a removal opening (4) for the granulate at the lower end of the cooling column as well as discharges for gaseous coolant (7). The device serves in particular for manufacturing frozen granulates of foods and pharmaceuticals. <IMAGE>
[GB1559920A]