baber/WOPTO huggingface dataset:
Patent EA-008463-B1 (EA)
Title: Drug delivery system for conscious sedation
Inventor: BURNS WILLIAM H JR
IPC: A61M31/00
Filed: 2002-10-17
Abstract: Inhalant anesthetics are developed with a number of properties including rapid onset and recovery, controllability, and, ideally, a broad safety profile. The efficacy of these agents is measured by their ability to create anesthesia within the framework of the other desirable properties. The instant invention focuses on the dosage level where analgesia occurs but amnesia or lack of consciousness does not. In addition to identifying the dosage level where pain is sharply reduced or eliminated but awareness remains, a delivery system for safe and effective delivery of the agent is described. The system comprises of a mated index system (10). Oxygen from the Osource (16) flows through a delivery manifold (22) including sensitive pressure regulator (18) to a flow meter (20).
Patent EA-006251-B1 (EA)
Title: 3-heteroaryl-3,5-dihydro-4-oxo-4h-pyridazino[4,5-b]indole-1-carboxamide derivatives, their preparation and therapeutic use
Inventor: BURNIER PHILIPPE
IPC: A61P25/16
Filed: 2002-11-20
Abstract: The invention concerns compounds of general formula (I), wherein: X represents a hydrogen or halogen atom; R1 represents a hydrogen atom or a (C1-C4)alkyl group; R2 and R3, represent each, independently of each other, a hydrogen atom or a (C1-C4)alkyl group, or R2 and R3 form, with the atom which bears them, a pyrrolidinyl, piperidinyl, morpholinyl or 4-alkylpiperazinyl group; and Het represents a heteroaromatic group of pyridinyl, 1-oxidopyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl, pyridazinyl type, the heteroaromatic group may represent one or several halogen atoms and/or one or several (C1-C4)alkyl, (C1-C4)alkoxyl groups; in the form of bases, addition salts to acids, solvates or hydrates. The invention also concerns pharmaceutical compositions containing same, methods for preparing same and synthesis intermediates.
Patent EA-007490-B1 (EA)
Title: N-aryl-2-axazolidinone-5-carboxamides and their derivatives and their use as antibacterials
Inventor: THOMAS RICHARD C
IPC: A61K31/5415
Filed: 2003-02-24
Abstract: Compounds of formula B-C-A-CO-NH-R, wherein A is structure i, ii or iii: formulae (I), (II), (III). C is optionally substituted aryl or heteroaryl, and C, B and Rare as defined in the invention and are useful as antibacterial agents.
Patent EA-008068-B1 (EA)
Title: Jet soil-suction device
Inventor: MELNIKOV VLADIMIR VASILIEVICH
IPC: E02F3/88
Filed: 2006-06-23
Abstract: The invention relates to hydraulic engineering and can be used in soil suction by dredgers.The inventive task is aimed at improving efficiency and production output of the device.The jet soil-suction device with a hydraulic cutter comprises a housing, a cover, a co-axially disposed suction pipe and a mixing chamber, a water supply pipe with an injection chamber, the side surface of the suction pipe forms a truncated cone with its bigger base facing the mixing chamber, the angle between the cone generator and its axis is 1-2°, two changeable protection bushes are mounted successively in the mixing chamber, the injection and mixing chambers are communicated through a toroidal channel made in the cover, wherein the cover is attached to the housing and the device itself to the pipings using tapered-flange couplings.
Patent EA-011699-B1 (EA)
Title: Method for producing finish line and device (embodiments) for producing thereof
Inventor: BORISOV IGOR ALEXANDROVICH
IPC: D05B3/02
Filed: 2007-03-30
Abstract: Several inventions relate to a method of producing a finish line and to a device for producing at least one space finish line by said method and can be used commercially and in household sewing machines. The method for producing a finish line is characterized in that during a reciprocating motion of a sewing machine needle holder with a main thread, positional relationship of finish threads is changed by means of a thread guide to the opposite relative to the sewing machine needle with the main thread, thus creating interweaving of finish threads fixing thereof by the main line at each padding of the sawing machine. According to the first embodiment of the invention a device for producing a finish line comprises a lever for kinematical connection with the needle holder and adapted to displace relative to the sawing machine presser, a thrust on the needle holder, a base, a movable thread feeder of the finish thread with a return spring, a movable bar and a drive. The base is adapted for connection with the sawing machine presser, the lever is kinematically connected with the movable bar and the base, the movable thread feeder of the finish thread is embodied as a thread guide mounted on an axis, at least one arm of which is provided with a thread grip, the thread guide axis is pivotally connected to the base and provided with an eccentric, the thread guide drive is kinematically connected with the movable bar by its one end, wherein by the other is pivotally connected with one of the thread feeder arm and provided with an elastic element connecting the drive with the thread guide axis. According to the second embodiment of the invention a device for producing a finish line comprises a lever for kinematical connection with the needle holder and adapted to displace relative to the sawing machine presser, a thrust on the needle holder, a base, a movable thread feeder of the finish thread, the arm is adapted for a kinematic connection with the needle holder by means of a thrust on the needle guide and with the base by means of guides and the elastic element and with the thread guide of the finish line by means of the drive. The thread guide of the finish line is embodied as at least one Γ-shaped arm pivotally connected in the top with the base, one arm of the thread guide is provided with the thread grip, and the other is pivotally connected with the drive connected to the arm by a hinge.
Patent EA-010927-B1 (EA)
Title: The use of free radical scavengers for protecting and treating skin and hair damages caused by chemotherapy
Inventor: GOLZ-BERNER KARIN
IPC: A61K47/02
Filed: 2006-05-04
Abstract: The present invention relates to the use of one or more free radical scavengers as prophylactically or therapeutically effective substances and microparticles having an average particle size ranging from 5 to 200 [mu]m for the preparation of a topical pharmaceutical composition for the protection or treatment of skin or hair damages caused by chemotherapeutic treatment.The invention also concerns a method for the protection or treatment of skin and hair damages of a mammal caused by chemotherapy.The invention further relates to a kit for the protection or treatment of hair damages caused by chemotherapeutic treatment consisting of a topical composition comprising microparticles together with free radical scavengers and a shampoo for an effective hair cleaning and supporting the hair treatment.A kit for the protection or treatment of skin damages caused by chemotherapy consisting of a topical composition comprising microparticles together with free radical scavengers and a cleansing milk for an effective skin cleaning and supporting the skin treatment is a further object of the present invention.
Patent EA-013971-B1 (EA)
Title: Microemulsions for for use in food and beverage products, a method for preparing thereof and microemulsion concentrates
Inventor: CHANAMAI RATJIKA
IPC: A23L29/00
Filed: 2006-10-10
Abstract: Oil-in-water microemulsions which can be used to incorporate lipophilic water-insoluble materials, such as beta-carotene, into food and beverage compositions are disclosed. The microemulsions utilize a ternary food grade emulsifier system which incorporates a low HLB emulsifier( HLB-value 1-5) , a medium HLB emulsifier (HLB-value 6-8) , and a high HLB emulsifier ( HLB- value 9-17) . Food and beverage products including the microemulsions are also disclosed. Finally, the method of preparing the microemulsions is described. The invention also encompasses water-in-oil microemulsions for use in incorporating water-soluble materials into food and beverage products. Finally, the invention encompasses concentrate compositions used for making those microemulsions.
Patent EA-016527-B1 (EA)
Title: Triazolopyridazine protein kinase modulators
Inventor: SMITH CHRISTOPHER RONALD
IPC: A61K31/5025
Filed: 2007-10-18
Abstract: The present disclosure relates to tirazalopyridazine protein kinase modulators selected from a group consisting of formulae defined in the description, or an enantiomer, diastereomer, racemate or pharmaceutically acceptable salt thereof. The invention also relates to the use of these compounds to treat diseases mediated by kinase activity, to use thereof for preparing a medicament for treating breast cancer, melanoma, lung cancer, colon cancer and other cancers. The invention also relates to a pharmaceutical composition containing claimed compounds.
Patent EA-018819-B1 (EA)
Title: Method for manufacturing absorbent article
Inventor: YAMAMOTO HIROKI
IPC: A61F13/15
Filed: 2009-06-23
Abstract: A method for manufacturing an absorbent article provided with a leg opening portion and a crotch portion and having an elastic member disposed extending from the leg opening portion to the crotch portion, comprising placing a continuum of the elastic members 4A and 5A in a desired layout, on at least one surface of a web 7A being transported continuously, while swinging the continuum of the elastic members 4A and 5A in a direction crossing a moving direction of the web 7A; feeding the web 7A on which the continuum of the elastic members 4A and 5A are placed, between a first roll 8, which is rotating in the moving direction, and a second roll 9; and pressing the continuum of the elastic members 4A and 5A and the web between the first roll 8 and the second roll 9; a recess 20 is formed in a predetermined pattern on at least an outer peripheral surface of the first roll 8, and the continuum of the elastic members 4A and 5A placed in an area corresponding to the crotch portion on one surface of the web faces the recess 20 and the obtained web 7A is connected to the second web 7B.
Patent EA-019409-B1 (EA)
Title: Device for cutting materials
Inventor: BARSUTCHI MAXIM
IPC: B28D1/22
Filed: 2011-03-04
Abstract: Device for cutting building materials contains an operating base (1) with a rest (15) and a gauge staff (16), two spring-loaded platforms (12) are mounted thereon, between which is fixed a supporting edge (2). On the columns (3), installed from the end faces of the operating base (1), is fixed a profiled guide rail (4), the vertical plane of which coincides with the vertical plane of the supporting edge (2), on the profiled guide rail (4) is mounted with a possibility of longitudinal movement a cutting carriage (5) on rollers (8). The rollers (8) are installed on bearings and correspond to the profile of the guide rail (4), from the end faces of which in supports are mounded breaking elongated two-stage tabs (7), symmetrically placed with respect to the cutting carriage (5) between which is placed a roller cutting blade (6), and in the upper part of the cutting carriage (5) on the axis is fixed a lever (10) with a handle (11) connected by rods (9) to the breaking elongated two-stage tabs (7).
Patent EA-019020-B1 (EA)
Title: Method of treating hemostasis disorders in brain contusion
Inventor: FATULLAEVA AIDA AGADADASH GYZY
IPC: A61P25/00
Filed: 2011-07-12
Abstract: The invention relates to medicine and can be used in a complex treatment of brain contusions. The essence of the invention is characterized in that from 250 to 1000 ml/kg of fresh frozen plasma is introduced to a patient organism daily during the first three days, after that perftoran is administered daily in 2-5 ml/kg dose to body mass and further clexane is administered in 20-60 mg/kg dose during 7-35 days.
Patent EA-022540-B1 (EA)
Title: Method and assembly for treating rainwater
Inventor: LEONARD OWEN THOMAS
IPC: C02F9/00
Filed: 2010-06-29
Abstract: The present invention is directed to an assembly and a method of treating rainwater to produce potable water. A compact and easy-to-install apparatus is achievable as a result of a simple, yet highly effective sanitisation method. Rainwater is entrained with a gas, and the entrained rainwater is irradiated with an ultraviolet (UV) light to fully sanitise the rainwater. The UV light is used during the irradiation of the entrained water and is also used to form a gaseous bactericide which is used to entrain the rainwater. None of the disadvantages of the prior art systems apply to any rainwater treatment systems which use this method. All of the connections between the component parts may be already provided for in this rainwater treatment unit, and consequently both installation and maintenance costs will be significantly reduced in comparison to the rainwater treatment systems which are known from the prior art.
Patent EA-031356-B1 (EA)
Title: Excision of transgenes in genetically modified organisms
Inventor: RUSSELL SEAN
IPC: A01H5/00
Filed: 2011-01-21
Abstract: A method for deleting a region of DNA in a plant. In some embodiments, the method comprises transforming a plant with a nucleic acid molecule, wherein the nucleic acid molecule encodes one or more zinc finger nuclease(s) (ZFNs) operably linked to one or more tissue specific promoter(s), e.g., a pollen specific promoter. Methods include excising native genes in a plant. Accordingly, in some embodiments, ZFNs are engineered that recognize sequences that flank native plant genes. In further embodiments, ZFNs are expressed under the control of developmental stage specific promoters, such that, for example, nucleic acid sequences are specifically excised in plants during relatively late stages of development. Nucleic acid molecules useful for carrying out disclosed methods and plants produced by the methods are included.
Patent EA-026281-B1 (EA)
Title: Method of treating or preventing malaria
Inventor: BOOLES CLIVE
IPC: A61P33/06
Filed: 2008-10-27
Abstract: The invention provides a method of treating or preventing malaria by administering to a patient a therapeutically effective amount a composition comprising artemether or arteether and one or more pharmaceutically acceptable excipients selected from the group consisting of triglycerides comprising a minimum of 95% of saturated fatty acids with between 6 and 12 carbon atoms; triglycerides with a chain length of less than 6 carbon atoms; omega-3-marine triglycerides; and fish oil, rich in omega-3-acids, said composition being formulated for transmucosal sublingual, buccal or nasal delivery, wherein said composition comprises less than 0.5% of water and less than 0.5% of ethanol.
Patent EA-027103-B1 (EA)
Title: Tolerogenic synthetic nanocarriers to reduce immune responses to therapeutic proteins
Inventor: FRASER CHRISTOPHER
IPC: A61K39/00
Filed: 2012-04-27
Abstract: Disclosed are synthetic nanocarrier compositions, and related methods, comprising therapeutic protein APC presentable antigens and immunosuppressants that provide tolerogenic immune responses specific to therapeutic proteins.
Patent EA-026452-B1 (EA)
Title: Centrifugal multistage electric pump
Inventor: YAZYKOV ANDREY YURIEVICH
IPC: F04D13/06
Filed: 2013-07-19
Abstract: A centrifugal multistage electric pump "VODOMET - WATER CANNON" comprises an electric motor 1, a capacitor box 2 and pump stages 3 housed in a casing 4 and aligned by covers 5 and 6, and by a support 7. An end shield 10 of the electric motor 1 is sealed by an elastic diaphragm 11. The capacitor box 2 is a leakproof cavity where the capacitor 13 and connectors 14 for connection of a cable 15 to windings of the electric motor 1 are placed. The box 2 accommodates a thermoswitch 30 disposed on a heat contactor 29. The pump stages 3 include impellers 19 and antifrictional washers 20. The impellers 19 are mounted on a hexahedral shaft 16. The washers 20 interact with axial supports in the form of ceramic inserts 21 that are inserted into the guide apparatus 22. The inserts 21 rest on shoulders protruding at the ends of the impellers 19. The guide apparatus 22 are sealed by radial seals and form a sealed packet together with pump stages 3. The packet of pump stages 3 rests on a support 28 integrated with an intermediate casing 26 where a seal 27 is mounted. The cover 25 and the casing 26 are arranged in series between the end shield 10 of the motor 1 and the coupling 18, the front cover plate 25 of the motor 1 has through openings 32, is supported, on one side, on a membrane 11 to form an annual cavity 33, and is sealed in respect of the shaft 17 of the electric motor 1 and to the inner wall of the casing 4 and the intermediate casing 26. The casing 26 is made in the form of a sleeve with a conical central projection 34 supported by the front cover 25 and sealed in respect of the shaft 17. The projection 34 is connected by a strap 35 to a peripheral annular sleeve 36 sealed in respect of the supports 7 and 28. The casing 26 has non-crossing openings 37, 38. The openings 37 are longitudinal, and the openings 38 are radial. The openings 37 are connected to the annular channels of the casing 4 and to the pressure side, and the openings 37 are connected to the suction side and to the cavity 33 between the diaphragm 11 and the cover 25. As a result, the pump reliability and durability are enhanced.
Patent EA-027903-B1 (EA)
Title: Adapter of an agricultural machine
Inventor: WALLACE DONALD JAMES STEERLING
IPC: A01D41/16
Filed: 2015-02-12
Abstract: The invention is related to agricultural machine-building, in particular, to mechanisms for attachment of a harvesting machine work tool. The technical result, namely, reduction of adapter bulkiness, simplification of the device design and operation, is achieved by provision of an agricultural machine adapter comprising a frame (1), follower assemblies (2) having holes for mounting retainers (8, 9), and pivotally mounted tie-rods (7), a support beam (5), a spring (23) having its one end fastened to the support beam (5) and the other connected to the frame (1), spring blocks (24), each having one end fastened to the frame (1) and the other to the follower assemblies (2) made in the form of levers, wherein, in accordance with the invention, the spring (23) fastened to the support beam (5) is disposed along the beam (5), the frame (1) includes side faces (25) consisting of ribs (26, 27, 28) connected in the form of a triangle, the follower assemblies (2) are L-shaped and have one of the lever arms fixed to the inclined rib (28) of the respective side face, and the spring blocks (24) are fastened to free ends of the other arms of the lever. Pivots for mounting tie-rods (7) are arranged on the side of the convex part (29) of the L-shaped levers.
Patent EA-033973-B1 (EA)
Title: Method for producing ceramic powder
Inventor: OKOVITYJ VYACHESLAV ALEXANDROVICH
IPC: C23C4/134
Filed: 2018-07-19
Abstract: The invention relates to the field of powder metallurgy, and particularly to methods for producing ceramic powders which can be used for obtaining thermal spray heat-protective coatings. The technical task solved by the invention consists in enhanced corrosion resistance to high temperature (at temperatures exceeding 1200°C) salt corrosion and corrosion in fuel combustion products containing sulfur, improved structure stability during long service life under loads, increased plasticity and cheapening of coating process due to the use of hafnium dioxide-zirconium dioxide partially stabilized with yttrium oxide as ceramic material. The set objective is achieved by the fact that in the method of producing ceramic powder comprising mixing of basic oxide and stabilizing oxide that is yttrium oxide, introduction of 8 wt.% of volatile binding agent, granulation at rotation speed of the rotary granulator drum of 30 rpm and inclination angle of 40°, drying at a temperature of 125°C for removal of the binding agent, sintering, fragmenting, screen sizing of powder in plasm, quench hardening of molten powder in 4-11% aqueous hydrochloric acid solution at solution temperature of 70-100°C and baking of the powder with subsequent cooling, where powder spraying in plasm and quench hardening is performed in a chamber filled with argon at the atmospheric pressure, hafnium oxide - zirconium dioxide composition is used as the basic oxide, powder granulation is carried out for 3.0-3.5 h, powder baking is performed at a temperature of 1850-1950°C for 5-7 h with subsequent cooling to 900°C at a rate 150-200°C/min and the power of plasm sprayer is 40 kW.
Patent EA-037092-B1 (EA)
Title: Tau-binding antibodies
Inventor: KNIGHT DAVID EDWARD ORMONDE
IPC: C07K16/18
Filed: 2016-07-05
Abstract: The invention relates to isolated Tau-binding antibodies or binding fragments thereof. The invention also relates to isolated nucleic acid molecules encoding the light and/or heavy chain of said antibodies, to a cloning or expression vector, to a host cell producing said antibodies, to a method of producing said antibodies and binding fragments thereof. Furthermore, the invention relates to the use of the antibodies and binding fragments thereof as a therapeutically active agent in treating a tauopathy, wherein the tauopathy is Alzheimer's disease or progressive supranuclear palsy, and to the use of the antibodies and binding fragments thereof as a diagnostic agent in diagnosing a tauopathy.
Patent EA-039777-B1 (EA)
Title: Polyol components and use thereof for the production of rigid polyurethane foams
Inventor: ZARBAKHSH SIRUS
Filed: 2018-03-23
Abstract: The invention relates to a polyol component P), a process for manufacturing rigid polyurethane foams and the use of a polyol component P) and rigid polyurethane foams.
Patent ES-2207369-B1 (ES)
Title: Maquina pesadora de envases llenos.
Inventor: PUCHALT CEA ANDRES
IPC: G01G11/00
Filed: 2001-10-24
Granted: 2005-07-16
Abstract: Máquina pesadora de envases llenos. Comprende una primera estación pesadora-cerradora (2) de los envases y un transportador (4) que los recoge y transporta, una cinta de pesaje sinfín (5), a la cual acceden los envases llenos uno a uno. La cinta de pesaje está montada sobre una estructura de soporte (9) a través de células de carga (10) amortiguadas. La máquina tiene unos medios discriminadores, para determinar si el peso detectado del envase que pasa sobre dicha cinta de pesaje se encuentra dentro de un intervalo predeterminado de pesos. Comprende también unos medios expulsores, constituidos por al menos un cilindro hidráulico o neumático (13), que actúa transversalmente al recorrido del envase (3) sobre la cinta auxiliar (12), para expulsar el envase en cuestión, en caso de que el peso obtenido del mismo quede fuera de dicho intervalo predeterminado. Aplicable en particular a bolsas de malla o cajas llenas, para frutas y verduras.
Patent ES-2247906-B1 (ES)
Title: Nuevas composiciones para materiales de construccion y sus aplicaciones.
Inventor: ARRIBAS AGUERO JOSE ALEJANDRO
IPC: C04B33/04
Filed: 2004-01-20
Granted: 2007-05-01
Abstract: Nuevas composiciones para materiales de construcción y sus aplicaciones. Dichas composiciones, constituidas esencialmente por 99,5-70% (p/p) de arcilla y 0,5-30% (p/p) de EVA, son particularmente útiles para su uso en los procesos de fabricación de piezas de construcción, los cuales comprenden una primera operación de extrusión y conformado de dicha composición seguida de una segunda operación de cocción de la pieza a 800-1000°. Dichas piezas (por ejemplo ladrillos, piezas de mampostería, etc.) tienen características especialmente idóneas para el sector de la construcción. Por su parte, dichas composiciones permiten aprovechar el EVA residual de la industria del calzado, con importantes repercusiones económicas y mediambientales.