Patent SG-11201801670Y-A (SG)
Title: Novel peptides and combination of peptides for use in immunotherapy against cll and other cancers
Inventor: MAHR ANDREA
IPC: C07K14/47
Filed: 2016-11-24
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -' Organization International Bureau res., 00) (43) International Publication Date ..... ..sr ,„,„.1 15 June 2017(15.06.2017) WIPO I PCT ID Hit (10) 1111111111111111111 WO International Ell 2017/097602 Publication 11111111111111111111111111t111111111IIIIII Al Number (51) International Patent Classification: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, C07K 14/47 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (21) International Application Number: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, PCT/EP2016/078718 KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, (22) International Filing Date: MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, 24 November 2016 (24.11.2016) OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, (25) Filing Language: English TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, (26) Publication Language: English ZW. (30) Priority Data: (84) Designated States (unless otherwise indicated, for every 1521746.6 10 December 2015 (10.12.2015) GB kind of regional protection available): ARIPO (BW, GH, 62/265,615 10 December 2015 (10.12.2015) US GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (71) Applicant: IMMATICS BIOTECHNOLOGIES GMBH TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, [DE/DE]; Paul-Ehrlich-StraBe 15, 72076 Tilbingen (DE). DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, L (72) Inventors: MAHR, Andrea; Kirschenweg 22, 72076 V, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, Tubingen (DE). WEINSCHENK, Toni; Im Morgenrain SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, 15, 73773 Aichwald (DE). WIEBE, Anita; Rosenstrasse GW, KM, ML, MR, NE, SN, TD, TG). 13, 72124 Pliezhausen (DE). SCHOOR, Oliver; Eich- Published: haldenstrasse 19, 72074 Tilbingen (DE). FRITSCHE, with international search report (Art 21(3)) Jens; Larchenweg 11, 72144 Dusslingen (DE). SINGH, — before the expiration of the time limit for amending the Harpreet; 2215 Dryden Rd., Houston, Texas 77030 (US). claims and to be republished in the event of receipt of (74) Agent: BOEHMERT & BOEHMERT; Krauss, Jan B., amendments (Rule 48.2(h)) Pettenkoferstrasse 20-22, 80336 Miinchen (DE). — with sequence listing part of description (Rule 5.2(a)) (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, 1-1 .4t ei O t--- cr\ (54) Title: NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST CLL AND O OTHER CANCERS IN (57) : The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In 1-1 c:::, particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor- associ - el ated T-cell peptide epitopes, alone or in combination with other tumor- associated peptides that can for example serve as active phar - 0 maceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and I transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.