baber/WOPTO huggingface dataset:
Patent CA-2126686-A1 (CA)
Title: Vaccination and methods against diseases resulting from pathogenic responses by specific t cell populations
Inventor: HOWELL MARK D
IPC: A61K48/00
Filed: 1992-12-21
Abstract: The present invention provides vaccines and a means of vaccinating a vertebrate so as to prevent or control specific T cell mediated pathologies, including autoimmune diseases and the unregulated replication of T cells. The vaccine is composed of a T cell receptor (TCR) or a fragment thereof corresponding to a TCR present on the surface of T cells mediating the pathology. The vaccine fragment can be a peptide corresponding to sequences of TCRs characteristic of the T cells mediating said pathology. Such a peptide can bind to conventional antigens complexed to MHC antigen presenting cells or to superantigens. Means of determining appropriate amino acid sequences for such vaccines are also provided. The vaccine is administered to the vertebrate in a manner that induces an immune response directed against the TCR of T cells mediating the pathology. This immune response down regulates or deletes the pathogenic T cells, thus ablating the disease pathogenesis. The invention additionally provides specific .beta.-chain variable regions of T cell receptors, designated V.beta.3, V.beta.4, V.beta.12, V.beta.14 and V, .beta.17, which are associated with the pathogenesis of autoimmune diseases, such as rheumatoid arthritis (RA) and multiple sclerosis (MS). Also provided are means to detect, prevent and treat RA and MS. Methods of administering DNA or RNA  encoding the polypeptides useful as vaccines of the present invention into the tissue cells of an individual is also provided.
Patent CA-2129738-A1 (CA)
Title: Slag control system
Inventor: LASZLO WILLIAM S
IPC: F27D3/15
Filed: 1993-02-05
Abstract: A method and apparatus for controlling slag in a tilting furnace (12). The apparatus (24) is mounted on a trough (22) extending from the furnace tap hole and has a reservoir (36) for receiving the flow from the trough (22). The reservoir (36) has a slag opening (52) and a bottom opening (68). A passage extends from the bottom opening along a weir (80) which terminates at an elevation above the bottom opening (68) but below the slap opening (52). The molten metal flows over the weir (80) and out of the device (24) and the slag is retained in the reservoir (36) and is discharged from the reservoir (36) through the slag opening (52).
Patent CA-2130685-A1 (CA)
Title: Stable polyisocyanate compositions obtainable by phosgene-free methods and their preparation
Inventor: LAQUA GERHARD
IPC: C07C265/14
Filed: 1994-08-23
Abstract: Abstract of the Disclosure Stable (cyclo)aliphatic polyisocyanate compositions obtainable by phosgene-free methods, preferably by thermal cleavage of (cyclo)aliphatic polycarbamates, are stabilized with carbon dioxide, advantageously in an amount of up to 0.3% by weight.
Patent CA-2130979-A1 (CA)
Inventor: COMBS JAMES L
IPC: G06F21/14
Filed: 1994-08-26
Abstract: A computer system for high-performance video and audio manipulations comprising a locked memory cartridge and an audio/video/compact disk (CD) drive controller/coprocessor.      The computer system has a central processing unit (CPU) with at least one bus associated therewith, with the bus having at least one bus line. The cartridge comprises a readable memory, a memory control circuit, a lock control circuit, and a connector all in circuit communication with each other. The connector allows the memory, the memory control circuit, and the lock control circuit to be pluggably connected in circuit communication with the CPU. The memory control circuit scrambles some of the bus lines, thereby scrambling the data in the memory on reset, and unscrambles the bus lines responsive to inputs from the lock control circuit. The lock control circuit monitors the bus, waiting for a proper combination of bus values to be asserted onto the bus, at which time the lock control circuit causes the memory control circuit to unscramble the bus lines. The audio/video/CD drive controller/coprocessor comprises a CPU interface, a CPU cache, a memory controller, a memory bus arbitrator, a DRAM refresher, a video controller, a CD drive controller, a digital signal processor (DSP) sound coprocessor, and a "blitter" graphics coprocessor in an integrated package.
Patent CA-2131685-A1 (CA)
Title: Mirror-mountable anti-dew fixture
Inventor: RAM JIGINDER
IPC: H05B3/84
Filed: 1994-09-08
Abstract: In a mirror-mountable anti-dew fixture providing a structure enclosing a sheet-type electrical heating element, the fixture consists essentially of two separable subassemblies: a routing subassembly for carrying wiring sub-wall to a power supplying hook-up point on a pre-existing circuit, and an envelope subassembly for holding the element.  Each of the subassemblies includes as a component an interlocking part of a separable termination enclosure formed when the two subassemblies are joined by uniting their respective interlocking parts.  The internal lead connections within the termination enclosure are also separable, using twist-cap connectors or similarly disconnectable means.  The envelope subassembly has a metal liner for flame-proofing and grounding purposes.  Use of this fixture is not restricted to one particular type of heating element, and it also presents the opportunity to upgrade subassemblies, since they can be fabricated in different versions, all having in common the unique interlocking parts which form the separable termination enclosure.
Patent CA-2133759-A1 (CA)
Title: Evaluation and treatment of patients with progressive immunosuppression
Inventor: OCHOA AUGUSTO C
IPC: A61P31/04
Filed: 1993-04-06
Abstract: A soluble immunosuppressive factor present in serum derived from tumor-bearing mammals, is associated with changes in TCR protein subunit levels, T lymphocyte signal transduction pathway proteins.  These changes provide a method of determining the level of immunosuppression in a mammal by determining the level of expression of at least one selected TCR subunit protein, a protein in the T lymphocyte signal transduction pathway, or of the NF-KB/rel family and comparing the level and pattern to chat found in non-immunosuppressed individuals: The method is useful to identify patients having T lymphocytes capable of acti-vation for immunotherapy and for identifying agents which cause or reverse immunosuppression. An isolated immunosuppres-sive factor associated with the level of expression of the proteins is useful for suppressing the immune response, for example, in organ transplantation.
Patent CA-2134064-A1 (CA)
Title: Automatic screw feeding mechanism for an automatic screw driving device
Inventor: CHEN ABRAHAM
IPC: B25B23/04
Filed: 1994-10-21
Abstract: An automatic screw feeding mechanism includes a feed belt receiving unit including a hollow housing which is provided with a limiting unit that is connected releasably to a stop unit of a hollow casing.  A feed belt extends into the housing.  A retaining unit is adapted to engage the feed belt to align a first screw with a tool bit of an automatic screw driving device which is connected releasably to and which extends into the casing.  A guide plate is connected to the housing and has a front end that is spaced apart from the housing and that is adapted to engage an operating surface.  An elongated guide unit is received in the casing and is connected releasably to the housing.  An actuating unit includes a seat member which is received in the casing and which is movable forward and rearward relative to the guide unit.   The casing normally engages the seat member so as to enable the seat member to move synchronously therewith relative to the guide unit from an initial position to a second position, wherein the tool bit extends into the housing to drive rotatably the first screw into the operating surface when the casing is urged by the automatic screw driving device.  The casing and the seat member are movable back to the initial position after the execution of the screw driving operation so that the retaining unit can align a second screw with the tool bit.
Patent CA-2139763-A1 (CA)
Title: Piezoelectric ceramic filter circuit and piezoelectric ceramic filter
Inventor: KATOH IKUO
IPC: H03H9/10
Filed: 1993-07-05
Abstract: Multiple piezoelectric ceramic filter elements have different center frequencies from each other and are cascade connected together. The piezoelectric ceramic filter elements satisfy the condition 0 ~dF0~ / BW3 < 0.8; where ~dF0~ is the absolute value of the frequency difference dF0 between the center frequencies, and BW3 is the band width, wherein the amplitude loss is 3dB or less.      Thereby, a low insertion loss and an improvement in the group delay characteristics can be compatible at the same time.
Patent CA-2140113-A1 (CA)
Inventor: KETTLE PAUL J JR
IPC: G05G5/08
Filed: 1995-01-12
Abstract: Apparatus for interlocking independent control handles for throttle action, dynamic brake action and reverser action, within a control stand for a railway locomotive to permit controlled removal of a reverser control handle in which a first and second cam disk are mounted to a first and second axle for rotation with a throttle handle and a dynamic brake handle such that the disk will interlock with each other so that neither the throttle or dynamic handle can be rotated unless the other is in an "off" position, and having a pivotal lock member secured to the reverser axle, with means thereon adapted to pivotally lock the reverser lever handle in place when it is secured to the reverser axle.     First and second arcuate guide means are provided to engage the pivotal  lock member throughout its pivotal rotation with the reverser axle, and include means thereon to permit the pivotal lock means to be pivoted to allow removal and insertion of the reverser lever handle when it is in the "neutral" position and the throttle and dynamic brake handles are in the "off" position.
Patent CA-2140381-A1 (CA)
Title: Method of locating the position of a fault on a power transmission line
Inventor: JOHNS ALLAN T
IPC: G01R31/08
Filed: 1995-01-17
Abstract: A method of locating the position of a fault on a power transmission line between first and second ends of the line comprising:  calculating the complex fault impedance at each of a plurality of assumed fault positions along the length of the line, the fault impedance at each assumed position being calculated utilising the measurement before and after fault occurrence of the voltage and current at the first end of the line, parameters of the line, and the impedance at the second end of the line; and selecting as the actual fault position the assumed fault position of the plurality of assumed fault positions for which the argument of the complex fault impedance most closely equals zero.  The method may be used with single or multi-phase power transmission lines.  There is also disclosed a method of determining the form of impedance network at a fault on a multi-phase power transmission line.
Patent CA-2141318-A1 (CA)
Inventor: BROWN DANIEL P
IPC: H04W4/16
Filed: 1994-04-23
Abstract: Radio frequency based telecommunication systems often require both subscriber units (100) and communications units (130) of a fixed network communication system to maintain secret data which may be used to verify authenticity as well as provide encrypting variables for message encryption processes. An efficient real-time authentication method and apparatus are provided which use a single message (210) to provide authentication and communication link setup information. Further, an authentication method and apparatus are provided which uses instant-specific information such as a time of day, radio frequency carrier frequency, a time slot number, a radio port number, access manager identifier, a radio port control unit identifier, or a base site controller identifier to enhance the reliability of the authentication process. Furthermore, a method and apparatus are provided for maintaining secure packet data communications through an encryption process by utilizing  a packetized message encryption key (502) and a unique packet number (504) as encryption variables.
Patent CA-2142458-A1 (CA)
Title: Machine and Method for Separating Recyclable Matter
Inventor: DAVIS ROBERT M
IPC: B07B4/04
Filed: 1993-08-11
Abstract: A machine (10) for sorting recyclable matter includes a trommel (14) for conducting and screening an input flow of recyclable matter and a magnetic mechanism (30) coupled to the trommel (14) for extracting magnetic material from the input flow while the trommel rotates. The input flow is dropped vertically from the trommel (14) into a positive-pressure air separator (44) which separates the flow into a first material stream (50) including lightweight articles and a second material stream (59) including relatively heavy articles. The heavy articles of the second material stream drop downwardly in the air separator (44). Padded baffles (49, 58) are provided in the air separator (44) for reducing the downward velocity of the second material stream (59), which substantially lowers breakage of glass articles.
Patent CA-2142527-A1 (CA)
Title: Light detector using reverse biased photodiodes with dark current compensation
Inventor: COROY TRENTON G
IPC: G01J1/44
Filed: 1995-02-14
Abstract: Light intensity detecting circuits using reverse biased photodiodes are disclosed. Two photodiodes are fabricated with essentially the same structure in close enough proximity to each other on a single semiconductor substrate so that they both experience the same environment. In one scheme the cathode of the first photodiode is common with the anode of the second photodiode and an inverting terminal of an operational amplifier with negative feedback. A negative voltage is applied to the anode of the first photodiode and a positive voltage of the same magnitude is applied to the cathode of the second photodiode. The output of the operational amplifier is proportional to the incident light provided the intensity on each photodiode are proportional to each other. In another circuit one of either the anodes or cathodes of each diode is common and the other is input into the inverting terminal of a separate operational amplifier. The outputs of each operational amplifier is input into a subtracter circuit to subtract common dark or photocurrent components so the output of the subtracter circuit is proportional to the difference in light incident on the photodiodes. The reverse bias across the photodiodes may be varied and this is of particular use for detectors whose spectral response may be shifted by means of, for instance the Franz-Keldysh or quantum confined Stark effects.
Patent CA-2143554-A1 (CA)
Title: Method and apparatus for cutting mailing machine roll tape
Inventor: GALLAGHER DENNIS M
IPC: B41J11/70
Filed: 1995-02-28
Abstract: A mailing machine for printing a postage indicia with or without an advertisement on envelopes and varying lengths of postage tape.  Also, a method of feeding, printing and cutting postage tape in a mailing machine.  The mailing machine includes: an elongate feed deck; a postage meter mounted in the mailing machine and having a printer downstream of the feed deck for printing a postage indicia with or without an advertisement on successive envelopes as they are fed along the feed deck or on postage tape; and a tape feeding and cutting apparatus mounted in the mailing machine for feeding postage tape to the postage meter for printing of the postage indicia with or without advertisement and for cutting the postage tape into finite lengths and ejecting the lengths of tape from the mailing machine.        The tape feeding and cutting apparatus includes: a device for storing a supply roll of tape of indefinite length; a device for feeding tape from the tape supply roll to the postage meter printer for printing of the postage indicia with or without advertisement on a portion of the tape; a device for sensing when the postage meter printer has completed printing the postage indicia with or without advertisement; a device for retracting an amount of tape from the postage meter printer as determined by the sensing device which will result in an appropriate, finite length of tape being cut by the tape feeding and cutting apparatus; a device for cutting the printed portion of the tape from the roll of tape; and a device for ejecting the cut, printed portion of tape from the mailing machine, whereby the cut, printed portion of tape includes only the amount of tape necessary for the printing of the indicia  with or without advertisement regardless of the length of any advertisement printed.
Patent CA-2143726-A1 (CA)
Title: Testing apparatus for the calibration of overheating and rail-brake locating devices
Inventor: SARIA OTHMAR
IPC: F16D66/00
Filed: 1995-03-01
Abstract: The  testing  apparatus  for  the  calibration  of overheating  or  standstill  [brake]  locating  devices comprises an IR emitter (15) which is guided in a housing so that it can shift along a guide (curved track) (16) and exhibits an appropriately adapted beaming direction (18) in the particular position.  An extension piece (29) is provided for further changing the beaming direction (18).
Patent CA-2144410-A1 (CA)
Title: Reducing galvanic degradation of hybrid metal/composite structures
Inventor: BOYD JACK D
IPC: C08K3/32
Filed: 1993-09-14
Abstract: Galvanic degradation under salt spray or salt water conditions in hybrid structures containing a corrosible metal and a conductive-fiber reinforced polymer matrix composite is reduced through the addition to the polymer matrix of the composite of an effective amount of an inorganic corrosion/degradation inhibitor.
Patent CA-2144765-A1 (CA)
Title: Metal casting unit and method of making
Inventor: WAGSTAFF FRANK E
IPC: B22D11/049
Filed: 1993-09-15
Abstract: In forming the casting unit (6) an intermediate casting (Figure 6) is made consisting of a monolithic body, which is annular in shape and has a vertical axis (10), an annular flange (72) outturned about the axis, a set of lugs (110) monolithically outstanding in the aperture thereof, and a groove (114) about the outer periphery of the casting in the upper portion, with mullions (20) monolithically upstanding, adjacent the outer periphery of the groove, to form ports (112) a series of holes (118) is drilled through the inner portion, to interconnect the groove with the cavity (108) in the lower end of the casting. Where the liquid coolant discharge means is a liquid coolant box, a leakage detector (17) is provided. The leakage is discharged at the bottom of the casting unit.
Patent CA-2145220-A1 (CA)
Title: Decoder and video apparatus including token generator and methods relating thereto
Inventor: WISE ADRIAN PHILIP
IPC: H04N7/50
Filed: 1995-03-22
Abstract: A multi-standard video decompression apparatus has a plurality of stages interconnected by a two-wire interface arranged as a pipeline processing machine.  Control tokens and DATA Tokens pass over the single two-wire interface for carrying both control and data in token format.   A token decode circuit is positioned in certain of the stages for recognizing certain of the tokens as control tokens  pertinent  to  that  stage  and  for  passing unrecognized   control   tokens   along   the   pipeline. Reconfiguration processing circuits  are  positioned  in selected stages and are responsive to a recognized control token for reconfiguring such stage to handle an identified DATA Token.  A wide variety of unique supporting subsystem circuitry and processing techniques  are disclosed for implementing the system.
Patent CA-2148444-A1 (CA)
Inventor: MONETTE ROBERT
IPC: B65G7/08
Filed: 1995-05-02
Abstract: La présente invention est un outil ou un appareil qui peut être d'utilisation manuelle ou utilisant une faible source d'énergie, servant à retourner des charges, notamment pour les transférer d'un support (palette) à un autre support (autres palettes, "slip sheet", ou autres), ayant la forme d'un fer à cheval ou d'un L, qui peut rouler sur 180 degrés ou 90 degrés respectivement. On l'utilise en fixant la charge dans l'appareil en alignant le centre de gravité de la charge et le centre de rotation de l'appareil et on le roule en le poussant ou en se servant d'un treuil pour le tirer.
Patent CA-2148898-A1 (CA)
Title: P54 stress-activated protein kinases
Inventor: KYRIAKIS JOHN M
IPC: C07K16/40
Filed: 1995-05-08
Abstract: The p54 Stress-Activated Protein Kinases (SAPKs) are members of a large gene family  and are structurally related to the previously described mitogen-activated protein kinases (MAPKs).  They are distinguished by their strong activation in response to heat shock, TNF-.alpha., IL-1-.beta., sphingomyelinases, chemical protein synthesis inhibitors, and ischemia.  These kinases have potential utility in the modulation of the inflammatory response and the up-regulation of repair or protective cellular proteins following injury or chemical insult.
Patent CA-2149878-A1 (CA)
Title: Electrochromic devices
Inventor: ELLIS FRANK B JR
IPC: G02F1/01
Filed: 1993-12-22
Abstract: Electrochromic devices (100; 110, 120, 130, 140, 150) are disclosed which may be used for large surface area applications. The devices utilize optical tuning layers (60, 61, 62, 53, 64, 65) to minimize optical interference between layers of the structure and to maximize uniform optical transparency. Optical tuning also enables transparent conductive oxide layers (20, 22) to be replaced by thin conductive metal layers (21, 23), thereby reducing the overall thickness of these devices and facilitating the manufacturing process.
Patent CA-2151394-A1 (CA)
Title: Improved beverages using tamarind extract
Inventor: ZABLOCKI LINDA
IPC: A23L27/30
Filed: 1994-10-19
Abstract: The use of an ingredient as a replacement for some or all of the acid in beverages is disclosed. Tamarind extract is used at low levels as a replacement for the phosphoric, citric or other acids conventionally found in carbonated soft drinks, flavored waters such as flavored waters, and iced teas. The resulting beverage has a higher pH, thus increasing the shelf life of beverages containing aspartame, as well as a flavor profile equivalent or better than convenional beverages sweetened with aspartame.
Patent CA-2152559-A1 (CA)
Title: Syringe assembly
Inventor: WATTS LENNOX O
IPC: A61M5/315
Filed: 1995-06-23
Abstract: A syringe assembly includes a barrel and a plunger slidably placed in the barrel. The plunger includes a shaft with a distal piston. The piston has a distal sealing portion with a distal surface including a central section and an outside section and a guide portion. The sealing portion has an outside diameter greater than the inside diameter of the barrel before the piston is placed in the barrel. The sealing portion has a groove in the distal surface where the central section flexibly joins the outside section. When the piston is placed in the barrel, the outside section contacts the barrel wall distally, deflecting the outside section with respect to the central section, forming a fluid tight seal with the barrel wall for facilitating drawing and expelling fluid with movement of the piston. The guide portion contacts the barrel wall to coaxially maintain the plunger in the barrel. The area of reduced thickness in the plunger sealing portion is formed as a living hinge by the part being distally flexed at the area of reduced thickness as the mold is opened. The plunger molding tool has a primary and a secondary opening mode. In the method of forming the plunger, the mold first opens in the secondary mode forming the living hinge, and then opens in the primary mode providing access to the part.