baber/WOPTO huggingface dataset:
Patent BR-112016029562-B1 (BR)
Title: métodos para tratar, diagnosticar e prognosticar uma malignidade hematológica
Inventor: RUTH MUÑOZ RISUEÑO
IPC: A61K31/473
Filed: 2015-06-26
Abstract: MÉTODOS PARA TRATAR, DIAGNOSTICAR E PROGNOSTICAR UMA MALIGNIDADE HEMATOLÓGICA A invenção se refere a um inibidor de receptor de serotonina (5-HTR) selecionado a partir do grupo que consiste em um inibidor 5- HTR do tipo 1 e um inibidor 5-HTR do tipo 2 para uso na prevenção e/ou tratamento de uma malignidade hematológica. Adicionalmente, a invenção se refere a métodos in vitro para a identificação ou isolamento de uma célula maligna de uma malignidade hematológica ou para diagnosticar uma malignidade hematológica com base na detecção da expressão de 5-HTR do tipo 1 e/ou 5-HTR do tipo 2. Além disso, a invenção se refere a métodos in vitro para determinar o prognóstico, para monitorar o efeito de uma terapia ou para projetar uma terapia personalizada em um indivíduo que sofre de uma malignidade hematológica com base na determinação dos níveis de 5-HTR do tipo 1 e/ou tipo 2 5-HTR.
Patent BR-112016029627-B1 (BR)
Title: Método para acabamento de engrenagens de metal temperado
Inventor: Enrico LANDI
IPC: B23F5/04
Filed: 2015-06-18
Abstract: MÉTODO PARA ACABAMENTO DE ENGRENAGENS DE METAL TEMPERADO É descrito um método para o acabamento de engrenagens de metal temperado (I), compreendendo uma primeira etapa de remoção a seco de uma primeira quantidade de porção de material (q1), por meio de uma primeira ferramenta de corte (11; 111) com bordas de corte definidas; e uma segunda etapa de remoção a seco de uma segunda quantidade de porção de material (q2), por meio de uma segunda ferramenta de corte (12; 112) com bordas de corte não definidas.
Patent BR-112016029761-B1 (BR)
Title: Composições compreendendo um derivado de ácido quinolona carboxílico e agentes efervescentes e uso das mesmas
Inventor: DANPING LI
IPC: A61K31/045
Filed: 2015-06-19
Abstract: COMPOSIÇÕES ANTIMICROBIANAS COM AGENTES EFERVESCENTES. A presente invenção refere-se a composições farmacêuticas compreendendo um derivado de ácido carboxílico de quinolona como agente antimicrobiano e um agente efervescente. Estas composições têm tolerabilidade gastrointestinal melhorada e/ou potencial reduzido para causar efeitos colaterais gastrointestinais. Estas composições são úteis para administração oral, para tratar, prevenir, ou reduzir o risco de infecções microbianas.
Patent BR-112017002933-B1 (BR)
Title: Sistema de afixação de membro de desgaste
Inventor: JOHN A RUVANG
IPC: E02F3/36
Filed: 2015-06-05
Abstract: SISTEMA DE AFIXAÇÃO DE MEMBRO DE DESGASTE. Um sistema de afixação de membro de desgaste para um implemento de escavação pode incluir um retentor com um apoio que engata um lado dianteiro de uma abertura que se estende através de um rebordo do implemento de escavação, o retentor incluindo adicionalmente um came. A rotação do came desloca o apoio para frente em relação a um corpo do retentor. Um outro sistema de afixação de membro de desgaste pode incluir um retentor com um came e um apoio. A rotação do came desloca o apoio para fora em relação a um corpo do retentor. O deslocamento do apoio é em uma direção ortogonal a um eixo geométrico de rotação do came
Patent BR-112017014870-B1 (BR)
Title: Composição de borracha, pneu e método de formação de um composto que contém a composição de borracha
Inventor: HOWARD A COLVIN
IPC: C08K3/36
Filed: 2016-01-12
Abstract: A presente invenção refere-se a uma composição de borracha que inclui borracha de guaiule e 15 a 90 phr de sílica. A borracha pode ser cis-1,4-cis-1,4-poliisopreno e incluir a 15 a 90 phr de sílica e conter menos de 20% das proteínas associadas com a borracha de Hevea e também incluir pelo menos um traço das resinas presentes em outras borrachas naturais. A borracha pode ser cis-1,4-poliisopreno e também incluir entre pelo menos um traço e 3% em peso das resinas presentes na borracha de guaiule. A composição de borracha também pode compreender uma borracha sintética e incluir entre cerca de 40 a 100 phr de borracha do guaiule, e sílica. A sílica pode ser hidrofobizada.
Patent BR-112017020916-B1 (BR)
Title: Processo de fermentação contínua para a produção de produto biológico
Inventor: FREDERICK R BLATTNER
IPC: C12M1/18
Filed: 2016-04-01
Abstract: MATERIAIS E MÉTODOS PARA FERMENTAÇÃO DE FLUXO CONTÍNUO ESTENTIDA DE BACTÉRIAS DE GENOMA REDUZIDO. Trata-se de um sistema de fluxo contínuo de dois vasos em conjunto com cepas bacterianas de genoma reduzido de mutação baixa que fornece uma plataforma para fermentações estendidas a longo prazo. Tais sistemas exigem modificação de dispositivos de fermentação padrão, como sondas, bombas e sistemas de monitoramento, bem como procedimentos aprimorados para entrega de alimentação, monitoramento de cultura e métodos de coleta de produto. Um sistema de dois vasos otimizado para produzir quantidades grandes de produtos de fermentação de volume pequeno, fermentações contínuas de longa duração representam um aprimoramento significativo em relação às estratégias de fermentação existentes. Métodos e composições para fermentação de fluxo contínuo a longo prazo com o uso de um aparelho de fermentação de cultura contínua de dois vasos são descritos.
Patent BR-112017024332-B1 (BR)
Title: Aparelho e método para gerar energia elétrica de corrente contínua em fundo de poço a uma tensão selecionada
Inventor: SEBASTIAN TEGELER
IPC: E21B41/00
Filed: 2016-05-11
Abstract: RETIFICADOR ATIVO PARA APLICAÇÕES DE FUNDO DE POÇO. Um aparelho para gerar energia elétrica de corrente contínua (DC) no fundo de poço a uma tensão selecionada inclui uma tubulação de broca, uma turbina para converter energia de fluxo de fundo de poço em energia rotacional, um alternador acoplado à turbina para fornecer energia elétrica AC e um retificador ativo configurado para corrigir a energia elétrica AC em energia elétrica DC em uma tensão controlável. O retificador ativo inclui (a) um circuito de ponte tendo um ramo de circuito tendo primeiro e segundo conjuntos de retificadores incluindo um comutador de semicondutores em paralelo com um diodo para cada fase da energia elétrica AC e (b) um circuito de controle de feedback com um microprocessador e configurado para receber uma medida de tensão de saída e uma medição de tensão e/ou uma medição de corrente em pelo menos um ramo de circuito como uma entrada e para fornecer um sinal de controle para cada comutador de semicondutor de modo a fornecer a energia elétrica DC à tensão selecionada.
Patent BR-112018006382-B1 (BR)
Title: Recipiente de transporte e armazenagem feito de material plástico para um material de enchimento
Inventor: BODO RICHTER
IPC: B65D90/46
Filed: 2016-12-29
Abstract: RECIPIENTE DE TRANSPORTE E ARMAZENAGEM FEITO DE MATERIAL SINTÉTICO PARA UM MATERIAL DE ENCHIMENTO. A invenção refere-se a um recipiente de transporte e armazenagem feito de material sintético para um material de enchimento, com um recipiente interno (14) de polietileno, produzido no processo de moldagem por sopro, com uma construção de parede de camada única. O recipiente interno (14) é recebido por um recipiente externo aberto em cima, o qual contém pelo menos uma camada de material sintético eletricamente condutivo. A superfície externa do recipiente interno (14) está envolta com um material flexível (16) dissipador de eletricidade, sendo que pelo menos uma tala (18) eletricamente condutiva cobre pelo menos uma parte do lado superior do recipiente interno (14).
Patent BR-122012009489-B1 (BR)
Title: Processo para produzir 2-etóxi-1-{[2’-(5-oxo-4,5-diidro-1,2,4-oxadiazol-3-il)bifenil-4-il]metil}-1h-benzimidazol-7-carboxilato de (5-metil-2-oxo-1,3-dioxol-4-il)metila ou um sal do mesmo, composição farmacéutica, e, uso
Inventor: HIROKI SAKAMOTO
IPC: A61K45/00
Filed: 2005-02-23
Abstract: composto ou um sal do mesmo, processo para produzir um composto, medicamento, e, uso do composto. a presente invenção está relacionada a um composto representado pela fórmula (i) onde r^2^, r^3^, r^4^, r^5^, r^6^, r^7^ e r^8^ são cada um independentemente um átomo de hidrogênio ou um c~1-6~ alquila, ou um sal do mesmo. o composto da presente invenção é útil como um agente para profilaxia ou para tratamento de doenças circulatórias tais como hipertensão e similares, e doenças metabólicas tais como diabetes e similares.
Patent BR-122017012510-B1 (BR)
Inventor: AKULA ANISHA
IPC: A01H5/00
Filed: 2007-08-31
Abstract: The invention provides methods for identifying regenerated transformed plants and differentiated transformed plant parts, obtained without subjecting plant cells to selective conditions prior to regenerating the cells to obtain differentiated tissues. In particular embodiments, the plant cells are corn plant cells. Methods for growing and handling plants, including identifying plants that demonstrate specific traits of interest are also provided.
Patent JP-2992240-B2 (JP)
Title: Prize ball counter for pachinko machine
Inventor: NAKABAYASHI HIDEO
IPC: A63F7/02
Filed: 1997-01-06
Granted: 1999-12-20
Abstract: PROBLEM TO BE SOLVED: To provide a prize ball counter with excellent durability which eliminates fear of overrun and moreover, enables smooth operation by enabling accurately counting of prize balls without requiring a larger motor. SOLUTION: A prize ball discharging member 8 which is rotated by a drive means is provided facing a prize ball introduction path 7. The prize ball discharging member 8 is provided with an induction part 13 which receives prize balls flowing in from the prize ball introduction path 7 to be dislocated to a position corresponding to a prize ball discharging path 12 and an working part 14 to push out the prize balls radially toward the prize ball discharging path 12. There is no rotary torque applied on the prize ball discharging member 8 thereby enabling smooth action.
Patent CS-212753-B2 (CS)
Inventor: BEAUCAMP KLAUS
IPC: C12Q1/60
Filed: 1978-01-23
Abstract: Reakční činidlo ke stanovení cholesterolu,
které se skládá z cholesterolesterázy
mikrobiálního původu a systému ke stanovení
volného cholesterolu, s výhodou cholesteroloxidázy
a systému ke stanovení peroxidu
vodíku nebo systému ke stanovení
cholesterolu, a to z cholesteroloxidázy, z
katalázy, acetylacetonu, methanolu a pufru
s obsahem amonných iontů, nebo je s výhodou
systémem ze stanovení peroxidu vodíku
peroxidáiza, chromogen a pufr, systémem
ke stanovení cholestenonu je hydrazinový
derivát, reagující s ketoskupinami za
vzniku hydrazinonu, například 2,4-dinitrofenylhydrazin,
a činidlo s výhodou obsahuje
povrchově aktivní činidlo, například hydroxypolyethoxydodekan.
Patent CS-221286-B2 (CS)
Title: Facility for blocking the axial shift of the hollow blooms
Inventor: ODENTHAL PETER
IPC: B21B21/04
Filed: 1981-02-04
Abstract: In the initial rolling of a hollow billet 16 the billet (16) is held against axial movement in the feed direction. This is accomplished using an abutment member (1) mounted relative to the roll stand (10) for movement into the roll gap from the side opposite the mandrel (15) upon which the billet (16) is borne. The abutment member (1) is held in its working position adjacent the plane containing the axes of the pilger rolls (14) during the initial rolling stage and then removed from the path of the rolled billet thereafter. The method reduces the high stresses suffered by the rolling mill. <IMAGE>
Patent CS-268172-B2 (CS)
Title: Microbicide
Inventor: STAUB THEODOR DR
IPC: A01N43/36
Filed: 1987-03-03
Abstract: 3-Cyano-4-(2,3-dichlorophenyl)pyrrole is suitable for controlling phytopathogenic microorganisms and is markedly superior in activity to preparation of a similar structure. Said compound may be employed for seed dressing, either along or in the form of compositions.
Patent CS-196434-B2 (CS)
Title: Method of preparing azo dyes
Inventor: SEILER HERBERT
IPC: C09B62/08
Filed: 1978-09-12
Abstract: Azo dyes of the formula    <IMAGE>  (1)  wherein D is a disulfonaphthyl-(2) residue, K is a naphtalene or benzene residue, R is hydrogen, and X is hydrogen, are especially suitable for dyeing of cellulosic materials of fibrous structure, they have a good exhaustion capacity and excellent dye fixation.
Patent JP-3116506-B2 (JP)
IPC: A23K1/16
Filed: 1992-01-17
Granted: 2000-12-11
Abstract: The process consists in feeding these animals with revivifiable spores of Bacillus cereus, strain C.I.P.5832.
Patent MD-1992-B2 (MD)
Title: Windmill
Inventor: GRIGOR FEODOR
IPC: F03D3/00
Filed: 1999-04-23
Abstract: The invention relates to devices for wind kinetic energy conversion into the mechanical one and may be used for obtaining of electric energy. Summary of the invention consists in the fact that the windmill contains a wind receiving device mounted onto the shaft, consisting of two disks, placed in parallel, between which there are fixed arched blades. The external edge of the blade is situated in the periphery of the disks and the internal edge is situated at a distance of 0,25...0,30 of the disk radius from the shaft. Inside the wind receiving device it is situated the chamber for liquid or gas fuel combustion.The result consists in increasing the windmill operation power and efficiency.Claims: 2Fig.: 8
Patent AU-651654-B2 (AU)
Title: Manufacture of water-swellable hydrophilic articles and drug delivery devices
Inventor: KUZMA PETER
IPC: B29C41/50
Filed: 1992-01-14
Granted: 1994-07-28
Abstract: A method of preparing a hydrophilic plastic cartridge by centrifugally casting polymerizable hydrophilic material in a rotating polymerization tube whose longitudinal axis is maintained parallel to the ground. The speed of rotation causes radial outward displacement of the polymerizable material which upon assuming a predetermined shape within the rotating tube is then polymerized to the predetermined solid configuration. The resulting plastic cartridge is characterized by smooth, unscored internal and external cylindrical surfaces. The cartridges are used as a rate-limiting membrane in drug delivery devices. Sterilized kits containing a disposable needle/syringe or trocar-like instrument and the drug delivery device are used for subcutaneous implantation of the device in an animal body.
Patent AU-714408-B2 (AU)
Title: Carbon-containing refractory and process for producing the same
Inventor: YAMAMURA TAKASHI
IPC: C04B35/532
Filed: 1996-12-13
Granted: 2000-01-06
Abstract: The object of the invention is to provide carbon-containing refractories which give off little decomposition gas having an offensive odor, exhibit excellent spalling resistance, and are equal or superior in kneading properties and molding properties to the refractories containing a phenolic resin as a binder; and a process for producing the same. To accomplished the object, the invention is characterized by replacing a conventionally employed phenolic resin binder with saccharified starch and/or reduced saccharified starch, a binder comprising 40% to 80% by weight of saccharified starch and/or reduced saccharified starch and 20% to 60% by weight of water, or a binder comprising 40% to 80% by weight of saccharified starch and/or reduced saccharified starch, 1% to 25% by weight of water, and 5% to 50% by weight of an alcohol having a boiling point of not lower than 80 DEG C.
Patent AU-717762-B2 (AU)
Title: Humanized antibodies to human gp39, compositions containing and therapeutic use thereof
Inventor: BLACK AMELIA
IPC: A61P11/06
Filed: 1996-11-07
Granted: 2000-03-30
Abstract: The present invention is directed to humanized antibodies which bind human gp39 and their use as therapeutic agents. These humanized antibodies are especially useful for treatment of autoimmune diseases.
Patent AU-661482-B2 (AU)
Title: Process for producing a storable azadirachtin-rich insecticide from sperm nuclei of the neem tree
Inventor: KLEEBERG HUBERTUS
IPC: A61K36/58
Filed: 1992-03-14
Granted: 1995-07-27
Abstract: Azadirachtin is effectively recovered from the seeds of the neem tree by crushing the seeds, extracting azadirachtin from the crushed seeds with water and then either extracting azadirachtin from the water using a non-aqueous solvent which is not miscible with water and has a higher solubility of azadirachtin than water or a surfactant having a turbidity temperature between 20 DEG  and 80 DEG  C. The concentrated azadirachtin is easily recovered from the second extraction solution and shows high activity as an insecticide.
Patent AU-570638-B2 (AU)
Title: Corticoid formulations
Inventor: STINDEL WOLFGANG
IPC: A61K9/06
Filed: 1983-07-01
Granted: 1988-03-24
Abstract: Topical preparations comprise jojoba oil and 0.005 to 2% by weight of an anti-inflammatory cortoicoid. The preparations are stable even when substantially diluted.
Patent AU-629171-B2 (AU)
Title: Method for enhancing the safety of metal-ligand chelates as magnetic resonants imaging agents and x-ray contrast agents
Inventor: VANDERIPE DONALD R
IPC: A61K49/06
Filed: 1988-05-12
Granted: 1992-10-01
Abstract: Paramagnetic chelates, as for example, Gadolinium diethylenetriaminepentaacetic acid (DTPA), manganese, ethylenediaminetetraacetic acid (EDTA), and others used as magnetic resonance imaging contrast agents are more toxic acutely when injected in high concentration or at rapid rates. The use of effective amounts of calcium in the form of, calcium chloride, calcium gluconate, or balanced salt solutions substantially reduces this toxicity without the need to add additional ligand.
Patent AU-763028-B2 (AU)
Title: Cables with a recyclable coating
Inventor: CASTELLANI LUCA
IPC: C08L23/08
Filed: 1999-12-21
Granted: 2003-07-10
Abstract: Cable, in particular for medium-voltage or high-voltage electrical power transmission or distribution, for telecommunications or for data transmission, comprising a conductor and at least one coating layer based on a non-crosslinked polymer material comprising a thermoplastic reactor elastomer with an ethylene-based elastomeric phase co-polymerized with an alpha-olefin and a propylene-based thermoplastic phase, in which the said elastomeric phase in the said thermoplastic reactor elastomer is at least 45% by weight relative to the total weight of the thermoplastic reactor elastomer, and the said thermoplastic reactor elastomer has value of enthalpy of fusion of peaks present below 130° C. and attributable to polyethylene sequences, such as HIFAX(R) KS080.
Patent AU-610640-B2 (AU)
Title: Straddling dowel
Inventor: BERGNER ARNDT
IPC: F16B13/08
Filed: 1988-09-09
Granted: 1991-05-23
Abstract: The expansion dowel, consisting of an anchor bolt (1) and an expansion sleeve (2), is radially enlarged by driving the expansion sleeve (2) onto a broadening (1e) of the anchor bolt (1), and is anchored in the drilled hole. The broadening (1e), designed as a concave bulge, results in an increasing conicity in the insertion direction, as a result of which the subsequent expansion of the expansion dowel is limited. Cutting teeth (2d, 2e, 2f), which are arranged on the front end region of the expansion sleeve (2) and have a saw-tooth-shaped profile, deposit a proportion of the retention material on the wall of the drilled hole, when the expansion sleeve is driven forward, and thus create an undercut. In order to attain easier deformability, the expansion sleeve (2) is provided on its outer side with a ring slot (2g) in the region adjacent to the cutting teeth (2d, 2e, 2f) in the direction opposite to the insertion direction. 
<IMAGE>
Patent AU-695790-B2 (AU)
Title: A push button flow stop useable with a disposable infusion pumping chamber cassette
Inventor: MINICK STEVEN E
IPC: A61M5/142
Filed: 1995-05-10
Granted: 1998-08-20
Abstract: A push button flow stop is mounted on a disposable infusion pumping cassette provided for use with a drug infusion pump. The flow stop is operative to enable or to block fluid flow through the cassette in a first mode and to monitor fluid pressure in the cassette in a second mode.
Patent AU-694243-B2 (AU)
Title: Compositions for topical administration of anesthetic agents
Inventor: MANTELLE JUAN A
IPC: A61K9/70
Filed: 1995-08-02
Granted: 1998-07-16
Abstract: A composition for topical application comprising a therapeutically effective amount of a pharmaceutical agent(s), a flexible, finite, pharmaceutically acceptable, adhesive, and a solvent for the pharmaceutical agent(s) in the adhesive and a method of administering the pharmaceutical agent to a mammal are disclosed.
Patent AU-669135-B2 (AU)
Title: Light valve employing a film comprising an encapsulated liquid suspension, and method of making such film
Inventor: CHECK JOSEPH ALOYSIUS III
IPC: C25D1/04
Filed: 1992-10-22
Granted: 1996-05-30
Abstract: A film (24) suitable for use as the light modulating unit of a light valve (27) comprises a cross-linked polymer matrix having droplets (26) of liquid light valve suspension distributed in the cross-linked polymer matrix, and a light valve comprising such a film.
Patent AU-577294-B2 (AU)
Title: Coating electrochemical electrode with permeable barrier plus active species
Inventor: DENEUFVILLE JOHN PETER
IPC: H01M4/38
Filed: 1984-06-25
Granted: 1988-09-22
Abstract: The present invention provides a coating for electrodes for use in electrochemical cells having an electrochemically active species and an electrolyte. The coating includes a selectively permeable material which allows for the diffusion of the active species through the coating during operation of the cell while providing a substantially impervious barrier to the electrolyte. Electrodes utilizing the coatings described herein may be used in primary and secondary cells over a wide range of operating temperatures to delivery better electrochemical performance even at room temperature. Methods of making the coating and an apparatus for performing these methods on a continuous basis are included in the present invention. A novel composition of matter also is contemplated containing lithium, silicon, and fluorine prepared by exposing lithium metal to SiF4.
Patent AU-617154-B2 (AU)
Title: New cephem compounds and processes for preparation thereof
Inventor: SAKANE KAZUO
IPC: A61P31/04
Filed: 1989-03-06
Granted: 1991-11-21
Abstract: A compound of the formula : <CHEM>  wherein R<1> is amino or a protected amino group,  R<2> is an organic group, R<3> is hydrogen, lower alkyl, hydroxy(lower)alkyl, protected hydroxy(lower)alkyl, amino(lower)alkyl, protected amino(lower)alkyl or an imino protective group,  R<4> is hydrogen, lower alkyl or lower alkylthio, A is lower alkylene which may be substituted with suitable substituent(s) and  Z is N or CH, and a pharmaceutically acceptable salt thereof, processes for its preparation and pharmaceutical compositions comprising them or a pharmaceutically acceptable salt thereof in admixture with pharmaceutically acceptable carriers.
Patent AU-755147-B2 (AU)
Title: Recombinant anti-tumor RNASE
Inventor: RYBAK SUSANNA M
IPC: A61K47/48
Filed: 1999-03-26
Granted: 2002-12-05
Abstract: This invention provides for new recombinant ribonuclease proteins which are active when expressed by bacteria. This allows the recombinant ribonucleases of this invention to be fused in-frame with ligand binding moieties to form cytotoxic fusion proteins. Furthermore, these proteins are more active than ribonucleases currently available even though the proteins of this invention lack an N-terminal pyroglutamic acid, which has been found to be necessary for ribonucleolytic activity. Because these proteins are recombinant proteins, mutations which increase cytotoxicity can be engineered.