baber/WOPTO huggingface dataset:
Patent CA-2443125-A1 (CA)
Inventor: VISSER HARRY D
IPC: F16G1/28
Filed: 2002-04-12
Abstract: A belt having a body (10), a tensile member (20) and an outer surface. The body comprises an elastomer. An outer surface of the belt having a profile, foe example teeth (15). A layer (30) of Ultra high molecular weight polyethylene thermoplastic (UHMWPE) is bonded to the profile surface. The layer bonded to the profile surface having a low softening point allowing it to conform to a mold shape prior to cure of the rubber body material. The layer having a molecular weight in the range of 3-7 million grams per mole.  The layer causes the belt to exhibit superior abrasion resistance and flexibility while reducing the cost per belt as compared to fabric jacket belts. The UHMWPE jacket belt has significantly reduced dust and debris production during operation.
Patent CA-2446055-A1 (CA)
Title: Pallet jig
Inventor: TREMBLEY ROBERT
IPC: B27F7/00
Filed: 2003-10-22
Abstract: Apparatus for building pallets comprises a jig frame adapted to maintain a plurality of deck boards in deck board locations on top of a plurality of stringers in parallel stringer locations. A gantry frame is mounted above the jig frame and a plurality of nailing guns is mounted on the gantry frame. The gantry frame is movable with respect to the jig frame to position and operate the nailing guns to nail deck boards to stringers. The nailing guns are mounted to the gantry frame such that they can move up and down with respect to the gantry frame, and the nailing guns are biased toward a lowest gun position. Each gun can move vertically so that when using uneven boards, all guns will fire.
Patent CA-2446097-A1 (CA)
Title: Apparatus for controlling a downhole drilling motor assembly
Inventor: WENZEL KENNETH H
IPC: E21B4/00
Filed: 2003-11-07
Abstract: An apparatus for controlling a downhole drilling motor assembly includes a tubular housing having an interior sidewall which defines an interior bore. A mandrel is rotatably mounted within the interior bore of the housing.  The mandrel has an exterior surface. A hydraulic dampener assembly is disposed between the interior sidewall of the housing and the exterior surface of the mandrel. The hydraulic dampener assembly limits the rate of rotation of the mandrel within the housing, thereby providing a preset resistance to reactive torque. The described apparatus can also be used as a steering tool by the addition of a feature that selectively blocks the flow of hydraulic fluids through the hydraulic dampener, thereby locking the mandrel in a selected directional position.
Patent CA-2448906-A1 (CA)
Title: Deployable ultrasound medical transducers
Inventor: DUNKI-JACOBS ROBERT J
IPC: A61B8/12
Filed: 2002-05-28
Abstract: An ultrasound medical system (94) includes a tube (96) and resiliently flexible fingers (98). The tube (96) has a distal end insertable into a patient and has a lumen (102) with a distal opening (104). The fingers (98) are extendable out of the distal opening (104) of the lumen (102) creating a deployed state and are at-least-partially retractable into the distal opening of the lumen creating a stowed state. Each finger includes an ultrasound transducer (106), wherein the distance between the transducers of adjacent fingers is greater in the deployed state than in the stowed state. In one example, at least one of the transducers is an ultrasound imaging transducer, an ultrasound medical-treatment transducer, or an ultrasound imaging and medical treatment transducer.
Patent CA-2454612-A1 (CA)
Inventor: GRZESEK ROBERT
IPC: G01S15/60
Filed: 2002-09-19
Abstract: An ultrasound transducer (12) is coupled to a transmitter (11) having a source of ultrasound signal. A receiving ultrasound transducer (13) is coupled to a preamplifier (14) and mixer (15). The mixer (15) is further coupled to a demodulator (16) and filter (17) which in turn is coupled to an amplifier (18) and a comparator (19). The comparator (19) output is coupled to a controller (20) which performs edge detection of the comparator output signal. The transmitter (11) produces ultrasound energy which is reflected from an object (31) to the receiving transducer (13). The shift in frequency between the transmitted ultrasound energy (30) and the reflected ultrasound energy (32) is used to determine the speed of the object (31) by employing Doppler effect.  Frequency detection is enhanced by mixing the transmitted and reflected ultrasound signals to provide a beat frequency signal.
Patent CA-2456565-A1 (CA)
Title: Effets phenotypiques des deficiences en ubiquinone et methodes de criblage de ces derniers
Inventor: GAO YUAN
IPC: C12N9/02
Filed: 2002-08-07
Abstract: La présente invention concerne une méthode de criblage d'un composé autorisant la survie d'embryons mutants homozygotes clk1; une méthode de criblage d'un composé approprié pour sauver un phénotype mutant d'une lignée cellulaire homozygote mclk1; une méthode de criblage d'un composé adapté pour le remplacement fonctionnel complet ou partiel d'ubiquinone endogène; une méthode de criblage d'un composé capable d'inhiber l'activité de clk-1 et/ou d'autres processus nécessaires pour produire l'ubiquinone à partir de déméthoxyubiquinone; une souris non productrice d'ubiquinone; une construction d'ADN, qui comprend une altération de mclk1; une lignée cellulaire ES ne produisant pas d'ubiquinone; un non producteur d'ubiquinone de sujet mutantcoq-3; une méthode de criblage d'un composé capable d'un remplacement d'ubiquinone ou de déméthoxyubiquinone fonctionnel complet ou partiel; une méthode de réduction et/ou d'augmentation du taux d'ubiquinone chez un sujet multicellulaire; une méthode de criblage d'un suppresseur génétique de clk-1; et une méthode de criblage d'un suppresseur génétique de coq-3.
Patent CA-2457423-A1 (CA)
Inventor: MAIER THOMAS
IPC: C12P19/38
Filed: 2004-03-03
Abstract: A method for fermentative production of S-adenosylmethionine (SAM), includes culturing a bacterial strain obtainable from a starting strain and having increased SAM-synthetase activity, compared to the starting strain, in a culture medium, the bacterial strain secreting SAM into the culture medium and the SAM being removed from the culture medium.
Patent CA-2459227-A1 (CA)
Inventor: HEUFT BERNHARD
IPC: B65C9/40
Filed: 2002-09-19
Abstract: The device serves to apply labels to containers (10), for example, drinks bottles. The orientation of the container (10) is determined by means of an electro-optical device (18) and corresponding signals are generated. Said signals control a device (24, 32) for turning the container to a set orientation, such that labels can be applied in a pre-determined position on the container (10).
Patent CA-2465370-A1 (CA)
Inventor: LEHMANN DIRK
IPC: B63H25/38
Filed: 2002-10-25
Abstract: The invention relates to a rudder for sea vessels, consisting of a main rudder and a fin which is coupled thereto by means of a vertical piston (15), restrictively guided by the main rudder and provided with a horizontal piston (11) The vertical piston (15) and the horizontal piston (11) are connected to each other via a hinge bolt to form a sliding pivoting piston coupling (100) and a bearing housing (16) of the vertical piston (15) is fixed to the hull of the vessel. In order to reduce the forces acting upon the sliding bearing of the vertical coupling bolt and horizontal pivoting bolt in addition to the hinge bolts connecting said bolts, the vertical piston (15) is supported by an additional counter bearing (27) on the hull of the vessel.
Patent CA-2468851-A1 (CA)
Title: Gips, a family of polypeptides with transcription factor activity that interact with goodpasture antigen binding protein
Inventor: SAUS JUAN
IPC: C12N5/10
Filed: 2002-12-05
Abstract: The present invention provides isolated GPBP-interacting 90 and 130 kDa polypeptides, and portions thereof (GIP90/130 polypeptides), antibodies to the GIP90/130 polypeptides, and pharmaceutical compositions thereof. The present invention also provides isolated GIP90/130 nucleic acid sequences, expression vectors comprising the nucleic acid sequences, and host cells transfected with the expression vectors. The invention further provides methods for detecting the GIP90/130 polypeptides or nucleic acid sequences, methods for inhibiting interactions between GPBP and GIP90/130 polypeptides, betwee pol k76 and GIP90/130 polypeptides or aggregation of GIP90/130 polypeptides, and methods for treating patients with autoimmune disorders or cancer.
Patent CA-2469351-A1 (CA)
Inventor: RUPP MICHAEL D
IPC: F24B1/191
Filed: 2004-05-31
Abstract: A prefabricated fireplace enclosure (10) configured and arranged for compact packaging which comprises first and second side panels (20,21), first and second mounting members (40,44) securable to the exterior wall of a building, a rear panel (22,23) and a bottom panel (24) adapted for positioning between the first and second side panels, and a roof assembly (25) adapted for support by the first and second side panels, wherein each of the panels, mounting members and roof assembly are configured and arranged so as to allow for compact packaging and shipment to the construction site in a disassembled condition.
Patent CA-2471938-A1 (CA)
Inventor: MIKI ICHIRO
IPC: C07K16/24
Filed: 2002-12-26
Abstract: L'invention concerne des médicaments préventifs ou des remèdes contre l'arthrite, des agents de protection du cartilage, des inhibiteurs de destruction des articulations et des inhibiteurs de la prolifération synoviale, contenant en tant que principe actif un anticorps de neutralisation anti-EGF8. L'invention concerne également des agents de diagnostic de l'arthrite contenant en tant que principe actif un anticorps anti-EGF8 et un procédé d'évaluation de l'arthrite à l'aide de l'anticorps.
Patent CA-2472522-A1 (CA)
Title: Multiple initial search method for cdma and gps systems
Inventor: POON WANG PAUL
IPC: H04W88/02
Filed: 2003-01-03
Abstract: Searcher hardware is multiplexed to perform simultaneous searches in either an IS-95 CDMA mode or a GPS mode. In the IS-95 mode, the search hardware is tim e- multiplexed into a number of searcher time slices, each of which can generat e a PN sequence to despread a data sequence. In the GPS mode, the search hardware is configured as a number of distinct GPS channels, each of which c an generate a Gold code sequence for tracking a GPS signal from a particular GP S satellite. This configuration allows the searcher to perform multiple GPS signal searches simultaneously. Signal searching in both IS-95 and GPS modes is performed at significantly higher speeds compared to conventional searche r hardware. Moreover, the search hardware can be dynamically configured to operate in either the IS-95 or the GPS mode, eliminating the need for dedicated circuitry for each mode of operation.
Patent CA-2472907-A1 (CA)
Title: Membrane filter housing and method of using the same
Inventor: KNOPS FRANCISCUS NICOLAAS MARI
IPC: C02F1/44
Filed: 2002-12-13
Abstract: The invention relates to a membrane filter housing, comprising a housing (1) with a feed inlet (2), a permeate outlet (3) and at least two membrane filters (4,4',4",4"') in the housing (1), wherein a fluid to be filtered is fed via the feed inlet (2) to the membrane filters (4,4',4",4"'), and a permeate stream is discharged via the permeate outlet (3) and wherein one of the permeate outlet (3) and the feed inlet (2) is located at least at one end (I) of the membrane filter housing (1) and the other one is located at a position (II) substantially in the middle of the membrane filter housing (1).
Patent CA-2477732-A1 (CA)
Inventor: OKADA MASAMICHI
IPC: A61K31/5377
Filed: 2003-03-19
Abstract: A novel aminomethyl-substituted thiazolobenzimidazole derivative represented by the following general formula (I) or a salt thereof. The derivative or salt has metabotropic glutamate receptor activity, has excellent oral activity, and is useful as a medicine. (I) (In the formula, R1 represents oxygenic saturated heterocycle, etc.; Alk1 represents lower alkylene; m is 0 or 1; Alk2 represents lower alkylene optionally substituted by oxo; n is 0 or 1; X represents a bond, oxygen, sulfur, or NR5; R3 represents hydrogen, etc.; and R2, R4, R5, R6, and R7 are the same or different and each represents hydrogen, etc.; provided that when X is a bond and n is 1, then R3 represents neither lower alkyl nor lower halogenoalkyl, and when m is 1, R1 is OH or OMe, Alk1 is C1-3 alkylene, and either 1) X is a bond, n is 1, and R3 is hydrogen or 2) X is a bond, n is 0, and R3 is cyclohexane, then R4 represents a group other than Me.)
Patent CA-2478640-A1 (CA)
Title: Method for selecting drug sensitivity-determining factors and method for predicting drug sensitivity using the selected factors
Inventor: ISHII NOBUYA
IPC: G16B40/00
Filed: 2002-03-13
Abstract: Based on drug sensitivity data and extensive gene expression data, a model was constructed by multivariate analysis with the partial least squares method type 1. Further, the model was optimized using modeling power and genetic algorithm. Thereby, the degree of contribution of the respective genes to drug sensitivity was determined to select genes with a high degree of contribution.  In addition, the levels of gene expression in specimens were analyzed, and then the drug sensitivity was predicted based on the model. The predicted values agreed well with those drug sensitivity values determined experimentally. The drug sensitivity-predicting method provided by the present invention enables assessment of the effectiveness of a drug prior to administration using small quantities of specimens associated with diseases such as cancer. Since this enables the selection of the most suitable drug for each patient, the present invention is very useful in improving a patient's quality of life (QOL).
Patent CA-2478758-A1 (CA)
Title: Pharmaceutical compositions comprising 2-(4-ethoxy-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo'1,5-bipyridazine in nanoparticulate form
Inventor: PEARSON STEPHANIE LYNN
IPC: A61P25/04
Filed: 2003-03-13
Abstract: The invention provides a pharmaceutical composition comprising a compound of formula (I) and pharmaceutically acceptable salts thereof, in which the compound is present in solid particles in nanoparticulate form, in admixture with one or more pharmaceutically acceptable carriers or excipients.
Patent CA-2479117-A1 (CA)
Title: Drop down stow in floor automotive vehicle seat assembly
Inventor: HOLDAMPF CARL J
IPC: B60N2/48
Filed: 2003-03-13
Abstract: A seat assembly (10) supports an occupant above a floor (7) having a load floor and a recess (6) extending therebelow. The seat assembly includes a seat cushion (12) extending between a seating surface (15) and a bottom surface (17). A riser mechanism (20) extends between the bottom surface (17) of the seat cushion and the floor (7) for allowing selective movement of the seat assembly between a seating position to support the occupant above the load floor and a stowed position disposed within the recess in the floor. A panel (70) is operatively coupled to the riser mechanism (20) for movement with the seat assembly between the seating position, wherein the panel (70) conceals the recess (6) in the floor, and said stowed position, wherein the panel is disposed within the recess to provide access thereto allowing the seat assembly to be stowed in the recess.
Patent CA-2480022-A1 (CA)
Title: Improved pressure container
Inventor: FLASHINSKI STANLEY J
IPC: F17C1/14
Filed: 2003-03-18
Abstract: A pressure container comprising axially extending side walls formed of plastic extending between a top end and a bottom end. A metal top is attached at a top seam in pressure-containing relation to the top end of the side walls, and a metal bottom attached at a bottom seam in pressure-containing relation to the bottom end of the side walls. Optional top and bottom beads are formed in the side walls to aid in sealingly securing the metal top and bottom to the side walls. A method for containing pressurized materials by providing and filling such a pressure container is also shown.
Patent CA-2480236-A1 (CA)
Title: Improved apparatus for the continuous separation of biological fluids into components and method of using same
Inventor: BRIGGS DENNIS
IPC: F04B43/12
Filed: 2004-09-03
Abstract: The present invention provides an apparatus for separating components of a fluid having an outer housing containing a core wherein three separate fluid pathways are provided to allow continuous separation of biological fluids.
Patent CA-2481149-A1 (CA)
Title: Combined hydrotreating process and configurations for same
Inventor: STUPIN STEVEN W
IPC: C10G45/00
Filed: 2002-04-05
Abstract: At least two feedstocks (210A) (210B) with different boiling point ranges are hydrotreated in an integrated hydrogenation plant (200) using an interbed separator (240) that is fluidly coupled between two hydrogenation reactors (230A) (230B). Contemplated configurations and methods will significantly reduce construction and operating cost by integration of at least two hydrogenation processes of two different feedstocks into one process, and/or by providing process conditions that reduce use of catalyst in at least one of the reactors.
Patent CA-2481432-A1 (CA)
Inventor: CASS RONALD
IPC: G06F15/18
Filed: 2003-04-18
Abstract: L'invention concerne un dispositif et un procédé permettant de traiter des données mixtes en vue d'une tâche sélectionnée. Un module de transformation d'entrée convertit ces données mixtes en données converties. Un module de mise en correspondance fonctionnelle traite les données converties de manière à produire une sortie fonctionnelle pour la tâche sélectionnée. La tâche sélectionnée peut être une tâche quelconque parmi diverses tâches telles que recherche, rappel, prédiction, classification etc. La tâche sélectionnée peut par exemple servir à l'exploration en profondeur de données, à l'exploration d'une base de données, à une promotion commerciale ciblée, à la détection de virus informatiques etc.
Patent CA-2481769-A1 (CA)
Title: Pouch for the blower unit of a powered air purifying respirator
Inventor: GLOAG NICHOLAS J
IPC: A62B18/04
Filed: 2003-03-19
Abstract: A pouch is provided for the blower unit of a powered air-purifying respirato r system, to isolate the blower unit from hazardous material such as potential ly- explosive dust or gas. The pouch has an opening at one end through which the blower unit can be inserted into the pouch, and is shaped at the other end t o receive the blower unit. It also has air inlet openings positioned to regist er with air inlets of the blower and permit the connection of the filter cartridges thereto, and an air outlet opening positioned to register with th e air outlet of the blower unit and permit the connection thereto of a breathi ng tube of the respirator system. When the blower unit is inside the pouch, sealing means at the pouch openings inhibit or prevent particulate or gaseou s material from entering the pouch through the openings.
Patent CA-2481810-A1 (CA)
Title: Shaft structure and bearing structure for tail end of rotor of gas turbine
Inventor: HIROKAWA KAZUHARU
IPC: F01D25/16
Filed: 2001-08-31
Abstract: A shaft structure of a rotor tail end of a gas turbine in which a steam passage for supplying and recovering a steam for cooling rotor blades of the gas turbine extends along a center axis of the rotor assembly of the gas turbine is provided, wherein a center hole of the rotor tail end coaxial to the center axis of the steam passage is formed in the rotor tail end. Provision is also made of a thermal sleeve between the steam passage and the inner surface of the center hole of the rotor tail end, so that a thermal insulation gas layer is formed between the inner surface of the center hole of the rotor tail end and the thermal sleeve. The thermal insulation gas layer is isolated gas-tightly and liquid-tightly from the outside.
Patent CA-2481813-A1 (CA)
Title: Antibody gene transfer and recombinant aav therefor
Inventor: CLARK KELLY REED
IPC: A61K39/00
Filed: 2003-04-09
Abstract: The present invention relates generally to the use of recombinant adeno-associated viruses (rAAV) for gene delivery and more specifically to the use of rAAV to deliver antibody genes to target cells in mammals. Administration of rAAV encoding antibodies that neutralize the HIV-1 virus is exemplified.
Patent CA-2485212-A1 (CA)
Title: 1-aza-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
Inventor: MERCEP MLADEN
IPC: C07D491/02
Filed: 2003-05-20
Abstract: The present invention relates to 1-aza-dibenzoazulene derivatives of formula I, to their pharmacologically acceptable salts and solvates, to process and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumour necrosis factor-.alpha. (TNF-.alpha.) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action. Wherein X may be CH2 or a hetero atom such as 0, S, S(=0), S(=0)2, or NRa, wherein Ra is hydrogen or a protecting group;  RI may be hydrogen, halogen, an optionally substituted C1-C7 alkyl or C2-C7 alkenyl, C2-C7 alkinyl, an optionally substituted aryl or heteroaryl and a heterocycle, hydroxy, hydroxy-C2-C7 alkenyl, hydroxy-C2-C7 alkinyl, C1-C7 alkoxy, thiol, thio-C2-C7 alkenyl, thio-C2-C7 alkinyl, C1-C7 alkylthio, amino, N-(C1~-C7)alkylamino, N,N-di(C1-C7-a1kyl)amino, (C1-C7-alkyl)amino, amino-C2-C7 alkenyl, amino-C2-C7 alkinyl, amino-C1,-C7 alkoxy, C1-C7 alkanoyl, aroyl, oxo~C1-C7 alkyl, C1-C7 alkanoyloxy, carboxy, an optionally substituted C1-C7 alkyloxycarbonyl or aryloxycarbonyl, carbamoyl, N-(C1-C7-alkyl)carbamoyl, N,N-di(C1-C7-alkyl)carbamoyl, cyano, cyano-C1-C7 alkyl, sulfonyl, C1-C7 alkylsulfonyl, sulfinyl, C1-C7 alkylsulfinyl, nitro, or a substituent of the formula II.
Patent CA-2485341-A1 (CA)
Title: Use of spliceosome mediated rna trans-splicing to confer cell selective replication to adenoviruses
Inventor: OTTO EDWARD
IPC: C12N5/10
Filed: 2003-05-08
Abstract: The present invention provides methods and compositions for conferring tumor selective cell death on cancer cells expressing specific target precursor messenger RNA molecules (cancer cell selective target pre-mRNAs). The compositions of the invention include conditionally replicative adenoviruses that have been genetically engineered to express one or more pre-trans- splicing molecules (PTMs) designed to interact with one or more cancer cell target pre-mRNA and mediate a trans-splicing reaction resulting in the generation of novel chimeric RNA molecules (chimeric RNA) capable of encodin g adenovirus specific protein(s). Adenovirus specific proteins include those proteins complementing an essential activity necessary for replication of a defective adenovirus. The methods and compositions of the invention may be used to target a lytic adenovirus infection to cancer cells thereby providin g a method for selective destruction of cancer cells. In addition, the adenoviruses of the invention may be engineered to encode PTMs designed to interact with target pre-mRNAs encoded by infectious agents within a cell, thereby targeting selective destruction of cells infected with such agents.< /SDOAB>
Patent CA-2487981-A1 (CA)
Inventor: RABIEA JEFFREY D
IPC: B65B43/26
Filed: 2003-05-30
Abstract: A method of using a plastic bag (10~) for point of sale purchase and a web of continuously attached length of plural bags (10) along a supply length by a perforated tear line (2). A seal (3) which runs codirectionally with the tear line (2) forms a closed bottom for each bag (10~), such that when a bag (10) is separated along the tear line (2) from a remainder of the supply, the bag (10~) is enclosed along three of its four edges enabling containment of produce or other items placed therein via the opening at the fourth, and remaining edge of the bag (10~) which is coextensive with the perforation line (2). The perforation tear line (2) cuts entirely through the continuous web supply of bags (10), however, the perforation along one side the bag (10~) is broken, such that the bag 10~) presents an open flap (4) through which contents can be added.