baber/WOPTO huggingface dataset:
Patent DE-68923298-D1 (DE)
Inventor: ANDERSON STEPHEN
IPC: C07K14/47
Filed: 1989-08-29
Granted: 1995-08-03
Abstract: Tissue plasminogen activator (t-PA) zymogens and variants are prepared, including a fibrinolytically active variant of t-PA that has an amino acid alteration at a site within the protease domain of t-PA as compared with the corresponding wild-type t-PA, which alteration renders the variant zymogenic in the presence of plasmin-degraded fibrinogen, and/or fibrin (or plasma clot) specific, as compared to the corresponding wild-type t-PA. DNA sequences can be prepared that encode the zymogens and variants, as well as expression vectors incorporating the DNA sequences, and host cells transformed with the expression vectors. The zymogens and variants may be used in a pharmaceutical preparation to treat a vascular disease or condition or to prevent fibrin deposition or adhesion formation or reformation in mammals.
Patent DE-68928034-D1 (DE)
Inventor: GUPTA KASHMIRI LAL
IPC: A01N25/26
Filed: 1989-06-08
Granted: 1997-06-12
Abstract: Disclosed is a porous protein particle for delivering over a period of time an active ingredient impregnated therein, and methods of making and using the same. The protein particles have a median size less than about 50 microns. Active ingredient entrapped in the porous structure is gradually released from the protein particle.
Patent DE-69000538-D1 (DE)
Inventor: T HOEN JAN
IPC: B60J1/00
Filed: 1990-01-30
Granted: 1993-01-21
Abstract: A vehicle, in particular a camper or caravan, has a double-walled window in one or more side walls (1). This window comprises a dish-shaped transparent plastic sheet (9) on the inside and a flat transparent plastic sheet (10) on the outside bonded by the peripheral edge thereto. The window is connected at its top edge by a hinge (7, 8). In order to enhance the appearance of the vehicle and reduce the air resistance by good streamlining, the outside surface of the flat sheet (10) lies essentially flush with the outside surface (5) of the side wall when the window is closed. A sealing section (11) which acts upon a vertical part of the peripheral edge of the dish-shaped sheet (9) when the window is closed is fixed on the inner peripheral edge (3) of the sash of the window. The sash edge (3) is of smaller thickness than the side wall (1) and abuts the inside surface (4) of the side wall. The distance between the outside of the sash edge (3) and the outside surface (5) of the side wall (1) is bridged by a stepped section (6) made of metal or plastic.
Patent DE-69010273-D1 (DE)
Inventor: SCHNEIDER EDWARD T
IPC: A61L2/26
Filed: 1990-04-25
Granted: 1994-08-04
Abstract: A liquid sterilizing system (A) defines a basin (10) in which a container (B) is removably disposed. The liquid sterilizing system selectively pumps sterile rinse liquids from a supply (24) and liquid sterilant solutions from a supply (70) into the basin filling the basin and the container. The container includes a lower shell having a bottom wall (34) that defines an aperture (32) for receiving sterilant and sterile rinse liquids. A nozzle plate (44) is mounted close to but spaced from the shell bottom wall to define a tortuous liquid distribution path (40) between the inlet aperture and nozzle plate apertures (90). A barrier (96) divides the liquid receiving portion and a drain portion of the liquid distribution path between the shell bottom surface and the nozzle plate. A cover (80) has a downward depending peripheral wall (82) which is offset from the shell peripheral wall (86) by the spacers (88) to define a tortuous vent path (48) therethrough. The container is lifted out by handles (100) which enable the container to be removed without disturbing the transparent cover, hence, without disturbing the sterile condition of the items within the container. In this manner, the sterilized items can be inventoried and maintained sterilized in the container for an extended duration.
Patent DE-69011637-D1 (DE)
Inventor: SVENSSON KURT
IPC: E21D13/02
Filed: 1990-11-21
Granted: 1994-09-22
Abstract: The present invention relates to a method for excavating and preparation of rock cavities and then substantially spherical rock cavities or rock cavities having spherically shaped parts, such as dome-shaped ceilings, which rock cavities are intended as shelter, for the storage of solid or liquid products or for production plants in rock, whereby one drills a first series of radially outwardly extending holes (6) from a first distance (4) from one or more shafts/tunnels (3, 13, 14, 15, 16), preferably radially arranged from the centre of a sphere projected; that one drills a second series of radially outwardly extending holes (8) from a second, far more out arranged distance (7) from the centre, which holes (8) extend outside the holes of the first series; that one drills a third series of radially outwardly extending holes (10) from a third, further far more out arranged distance (9) from the centre, which holes (10) extend outside the holes (8) of the second series; that optionally further series of holes (12) are drilled from further far out situated distances (11) extending radially outwardly up to the boundaries of the cavity (1); that the first series of holes (6) are charged in their whole lengths; that each further series of holes (8, 10, 12) are charged in that part which lies outside a charging area of a previous series of holes (6, 8, 10) up to the touching point of a next series of holes (10, 12), whereby the charges will take consecutive annular charging areas, which cover the shape of the spherical cavity projected, and that blasting takes place of each annular area per se starting from outside in, or vice verse. <IMAGE>
Patent DE-69020752-D1 (DE)
Inventor: MORISAWA YASUHIRO
IPC: C07D277/30
Filed: 1990-02-16
Granted: 1995-08-17
Abstract: Compounds of formula (I): <CHEM> [in which: R<1> is heterocyclic group having 5 or 6 ring atoms, or -NR<7>R<8>, where R<7> is alkyl and R<8> is optionally substituted phenyl, optionally substituted phenylalkyl or cycloalkyl; R<2> is optionally substituted phenyl or naphthyl; R<3> is thiazolyl; R<4> is cyclohexyl or isopropyl; R<5> is alkyl; and R<6> is alkyl] and salts thereof have renin-inhibitory and, hence, hypotensive activities and are of value in the diagnosis and treatment of hypertension induced by failures in the renin-angiotensin system. They may be prepared by reacting together appropriate amino acids or derivatives thereof.
Patent DE-69021019-D1 (DE)
Inventor: SCHWABE KLAUS-PETER DR
IPC: A61K36/16
Filed: 1990-12-03
Granted: 1995-08-24
Abstract: The invention relates to an improved extract from Ginkgo biloba leaves, a method of preparation of the same and pharmaceuticals containing the extract.
Patent DE-69032980-D1 (DE)
Inventor: HSU JEMIN CHARLES
IPC: A01N43/80
Filed: 1990-11-02
Granted: 1999-04-08
Abstract: Synergistic microbicidal compositions are disclosed, comprising 4,5-dichloro-2-octyl-3-isothiazolone and tetrachloroisophalonitrile for more effective, and broader control of microorganisms in various systems.
Patent DE-69034025-D1 (DE)
Inventor: FIELDS JAMES R
IPC: B22D17/30
Filed: 1990-03-06
Granted: 2003-01-16
Abstract: This invention concerns an aluminum alloy casting characterized by an iron content of less than about 0.5% by weight, and a gas content of less than or equal to 5 milliliters (STP) per 100 grams of aluminum, said casting having a yield strength in tension (0.2% offset) greater than or equal to 110 MPa and a free bend deformation greater than or equal to 25 min.
Patent DE-69104205-D1 (DE)
Inventor: VONKEN HAROLD
IPC: E04C2/288
Filed: 1991-07-03
Granted: 1994-10-27
Abstract: Wall element system comprising construction components (1) to be used in semi-permanent construction. Each of these construction components (1) is composed of concrete slabs (2) with insulating material (3) between them. A profile (4) is fitted around each construction component (1) so that they can be linked together. These profiles (4) are placed between the concrete slabs (2) and do not protrude from them. The wall component system includes coupling elements (7) to be placed in the profiles (4) to link construction components (1) vertically.
Patent DE-69107620-D1 (DE)
Inventor: PEDERSEN LARS
IPC: D21C5/00
Filed: 1991-08-21
Granted: 1995-03-30
Abstract: A process for treatment of lignocellulosic pulp comprising a multistage washing of the unbleached kraft brown stock and a xylanase treatment. The xylanase treatment is carried out in a holding tank introduced upstream the first washing unit or downstream one or more of the other washing units except for the last washing unit.
Patent DE-69111431-D1 (DE)
Inventor: SCHOELPPLE GUNTHER
IPC: G03B42/02
Filed: 1991-11-15
Granted: 1995-08-24
Abstract: PCT No. PCT/EP91/02156 Sec. 371 Date Jul. 21, 1992 Sec. 102(e) Date Jul. 21, 1992 PCT Filed Nov. 15, 1991 PCT Pub. No. WO92/09925 PCT Pub. Date Jun. 11, 1992.The device comprises a support element (6) arranged in parallel with the free end of a cassette lid (1b) which is to be opened. The support element is driven by a lever gear (7, 8, 9, 33, 34, 35) and, guided on arms (2, 3), can be lifted and lowered. Spring-biased pressure bolts (19, 20) guided on the support element (6) serve to reduce the pressure exerted on the cassette locking mechanism (1c, 1d) during unlocking as well as to close the cassette 1. A mounting plate (23) on which an unlocking member (25, 36) and its driving rotary magnet (26) are arranged is spring-biased into contact with the pressure bolts (19, 20). Moreover, an opening element (15) with check arms (15a, 15b) associated with the cassette lid (1b) is also pivotably mounted on the support element (6) and can be brought into an operative position in response to the position of the unlocking member (25, 36) and the position of the support element (6) respectively.
Patent DE-69116582-D1 (DE)
Inventor: PROTASI OTELLO
IPC: C07K14/565
Filed: 1991-03-12
Granted: 1996-03-07
Abstract: A process for the chromatographic purification of recombinant human beta -interferon wherein:   a) an aqueous solution of recombinant human  beta -interferon in unrefined state is contacted with a siliceous solid matrix equilibrated with deionized water and then eluted with appropriated eluant; b) the eluted fractions containing the recombinant human  beta -interferon purified according to the stage a) are loaded on a cation exchange resin; thereafter the rhu- beta -interferon adsorbed upon said matrix is eluted with an appropriated eluant.   The recombinant human  beta -interferon purified in this way is specifically useful as active agent in the production of pharmaceutic preparations suitable for the treatment of viral infections, tumors and as immunomodulators. <IMAGE>
Patent DE-69129385-D1 (DE)
Inventor: TANIGUCHI TOMOHIKO
IPC: G10L19/08
Filed: 1991-06-18
Granted: 1998-06-18
Abstract: A speech coding system operated under a known code-excited linear prediction (CELP) coding method. The CELP coding is achieved by selecting an optimum pitch vector P from an adaptive codebook and the corresponding first gain and, at the same time, selecting an optimum code vector from a sparse-stochastic codebook and the corresponding second gain. The system of the present invention is featured by special code vectors to be loaded in the sparse-stochastic codebook, which code vectors are hexagonal lattice code vectors each consisting of a zero vector with one sample set to +1 and another sample set to -1. <IMAGE>
Patent DE-69203117-D1 (DE)
Inventor: ALLEN PHILIP R
IPC: D21H19/18
Filed: 1992-03-11
Granted: 1995-08-03
Abstract: A method of producing a simulated watermark in which intense, focused heat is momentarily applied, in the desired watermark pattern, onto a thin solid matrix of waxy material placed in contact with a sheet of uncoated paper. This results in impression of a durable translucent mark. The wax penetrates the paper without the need either for chemical action or the application of significant direct pressure, and creates regions of translucence in the paper fibers.
Patent DE-69205737-D1 (DE)
Inventor: CHEN SHIH-RUEY THOMAS
IPC: C08F26/02
Filed: 1992-06-26
Granted: 1995-12-07
Abstract: Ampholyte terpolymer conditioning additives for hair care products are disclosed which improve wet and dry hair combability, especially detangling and reduced static flyaway, sheen, and fixative properties, especially curl retention. The ampholyte terpolymers may have a weight average molecular weight of from about 10 thousand to 10 million, and comprise (a) from at least 1 to as much as 95 weight percent of the nonionic monomer acrylamide (AM), (b) from at least 5 to as much as 80 weight percent of the cationic monomer dimethyldiallylammonium chloride (DMDAAC), and (c) from at least 1 to as much as 75 weight percent of the anionic monomer 2-acrylamido-2-methylpropane sulfonic acid (AMPSA), with optionally up to 50% of said anionic monomer AMPSA being replaced with the anionic monomer acrylic acid (AA). The ampholyte terpolymers are added to hair care product formulations in amounts ranging from 0.1-10% by weight. They are particularly compatible with anionic surfactant shampoos, providing clear formulations without the loss of conditioning properties described above.
Patent DE-69211988-D1 (DE)
Inventor: BERGE RICHARD
IPC: E04H1/12
Filed: 1992-04-10
Granted: 1996-08-08
Abstract: A panel system (10) has panels (12) disposed side by side and connected together by connecting elements (14). The elements (12, 14) are constructed from cardboard or plastics sheets. The connecting elements may have line slots (36, 38) or centre apertures (37) which form slots when the connecting element is folded and which grip folded back edges (50, 52) of adjacent panel elements, while dovetail slots (22, 24) in the panel edges retain the connecting elements in position, once the latter have been partially unfolded after insertion.
Patent DE-69216160-D1 (DE)
Inventor: DIVALL JOHN EDWIN
IPC: B67C3/00
Filed: 1992-06-22
Granted: 1997-02-06
Abstract: A method of filling a can with a non-carbonated product comprises in sequence the steps of (a) filling an open topped can with the product to leave a headspace; (b) blowing a permanent gas into the headspace to substantially fill the headspace and displace water vapour form the headspace; (c) seaming a can end onto the can to close the can; and (d) deforming the can end or can bottom from a first stable shape to a second stable shape so reducing the headspace volume and increase the headspace pressure to a level such that in anticipated conditions of processing, transit and storage the internal pressure remains above 1 atmosphere. The benefits arising are that cans having a thin side wall are supported against abuse or collapse and the cans remain in their desired shape. <IMAGE>
Patent DE-69226774-D1 (DE)
Inventor: WILSON JEFFREY
IPC: H04M3/533
Filed: 1992-06-03
Granted: 1998-10-01
Abstract: PCT No. PCT/GB92/01000 Sec. 371 Date Dec. 3, 1993 Sec. 102(e) Date Dec. 3, 1993 PCT Filed Jun. 3, 1992 PCT Pub. No. WO92/22165 PCT Pub. Date Dec. 10, 1992A voice services equipment includes a voice services module with a plurality of audio ports and a switching device responsive to an interactive control signal from a call control processor of the module to provide a selectable switching function between the audio ports of the module and a plurality of connections to a telephone network. The VSE is user programmable and includes a plurality of connections for incoming calls via an interface and a plurality of connections for outgoing calls via an interface. The switching device can switch between selected combinations of incoming call connections, outgoing call connections and the audio ports of the module. The switching device can thus connect a caller to a called party via the incoming and outgoing connections, and keep monitoring the call for billing purposes or in order to provide a follow-on call.
Patent DE-69229478-D1 (DE)
Inventor: MCGEEHAN JOHN
IPC: B01L3/00
Filed: 1992-08-14
Granted: 1999-07-29
Abstract: An analytical device for fluid samples includes a fluid sample well means connected to a sample initiation area in such a fashion that the assay will not commence unless sufficient sample is introduced into the sample well means to conduct the assay. Once sufficient sample has been deposited into the sample well means, the sample flows into an initiation area and the assay commences.
Patent DE-69229902-D1 (DE)
Inventor: HILAL NABIL
IPC: A61B19/00
Filed: 1992-02-12
Granted: 1999-10-07
Abstract: A surgical trocar includes an operative sleeve adapted for disposition across a tissue barrier and an obturator removably disposed in the sleeve. A source of energy is introduced to a cutting element disposed at the distal end of the obturator for energizing the cutting element to cut tissue barrier. The distal end of the obturator and the distal end of the operative sleeve can be advanced through the cut tissue and the obturator removed leaving the sleeve operatively disposed for further surgery.
Patent DE-69233075-D1 (DE)
Inventor: TAYLOR JAMES MARTIN
IPC: D06L4/614
Filed: 1992-03-25
Granted: 2003-06-26
Abstract: A process for treating a solvent-spun cellulose fibre to reduce its fibrillation tendency is disclosed which is characterised in that a substantially colourless chemical reagent having from two to six functional groups reactive with cellulose is applied from an aqueous system to never-dried solvent-spun cellulose fibre and is caused to react therewith under alkaline conditions.
Patent DE-69306884-D1 (DE)
Inventor: HALL DAVID
IPC: B65G23/08
Filed: 1993-02-08
Granted: 1997-02-06
Abstract: A drive pulley assembly is disclosed for a conveyor belt assembly which permits a reduction in the overall size of the conveyor assembly without any reduction in the size or width of the conveyor belt. The overall width of the conveyor assembly is reduced by providing recessed end cavities in the ends of the drive pulley to accommodate the mounting brackets for the pulley. In accordance with the present invention, the mounting brackets are secured to the inside of respective frame members and extend therefrom into the recessed end cavities of the drive pulley such that substantially the entirety of the mounting bracket lies within the drive pulley. Because the mounting brackets are contained substantially within the confines of the drive pulley, the drive pulley assembly of the present invention requires less space than conventional conveyor assemblies in which the mounts are disposed beyond the ends of the drive pulley.
Patent DE-69308454-D1 (DE)
Inventor: COOPER LEONARD
IPC: B65D71/48
Filed: 1993-04-28
Granted: 1997-04-10
Abstract: A paperboard clip-type carrier especially suited for carrying beverage cans. The top panel comprises overlapped inner and outer top panel flaps which provide double thickness in the handle area. Support edges in reinforcement sections connected to the bottom panel and the side panels engage the underside of the can chimes to support them, and stress relief score lines are provided to distribute stresses from the support edges through the reinforcement sections. The side panel has cutouts through which the can chimes can protrude, allowing the side panels to be positioned tightly against the cans to increase the strength of the carrier.
Patent DE-69315648-D1 (DE)
Inventor: ARTZ LARRY
IPC: B60R22/10
Filed: 1993-09-03
Granted: 1998-01-22
Abstract: A child seat device (10), for use in a vehicle having a seatbelt (12) for securing the child seat device to the vehicle seat (14), has an inflatable child seat (20) which includes an inflatable bottom panel (22), an inflatable back panel (24) upstanding from the rear of the bottom panel, and a pair of opposed, laterally-spaced inflatable sidewall panels (26). Each of the sidewall panels (26) has a back portion (30) projecting forwardly from a respective side of the back panel and a bottom portion (32) projecting upwardly from a respective side of the bottom panel. An inflatable brace (50) disposed in each of the sidewall panels intermediate the back and bottom sidewall portions, limits pivotal movement of the back and bottom sidewall portions towards one another. Each of the braces (50) defines a single interior air chamber having, at most, limited gaseous communication with the bottom, back and sidewall panels. Alternatively, a substantially rigid frame (200) is secured to the back panel (24) for movement therewith as a unit, thereby to limit pivotal movement of the back and bottom panels (24,22) towards one another. The frame (200) defines a pair of apertures (212) configured and dimensioned to receive therethrough a seatbelt (12), thereby to secure the device (100) to the vehicle seat (14). A releasable harness (62') maintains the torso of a child (c) intermediate the sidewall panels (26). <IMAGE>
Patent DE-69320173-D1 (DE)
Inventor: KLAVENESS JO
IPC: A61B5/05
Filed: 1993-01-04
Granted: 1998-09-10
Abstract: PCT No. PCT/EP93/00006 Sec. 371 Date May 4, 1995 Sec. 102(e) Date May 4, 1995 PCT Filed Jan. 4, 1993 PCT Pub. No. WO93/12717 PCT Pub. Date Jul. 8, 1993Agents for use in improving tissue/tissue contrast in electrical impedance tomography are described. In particular triiodophenyl compounds, metal chelates, magnetic particles, conducting particles and microbubbles may be used.
Patent DE-69403199-D1 (DE)
Inventor: FACCIOLI GIOVANNI
IPC: A61B17/64
Filed: 1994-02-25
Granted: 1997-06-19
Abstract: An auxiliary device for use in the external setting of fractures is particularly adapted for use in association with an external axial fixator or splint having bolt-holding clamps with spherical joints for fixing bone bolts or screws which can be implanted in fractured pieces of bone. The auxiliary device comprises a central body which can be elongated axially and has end portions which can be releasably coupled to corresponding bolt-holding clamps on an external axial fixator or splint associated therewith; the said end portions are attached to the central body by means of corresponding hinges having hinge axes (20, 20') which are retained in parallel relation to each other and perpendicular to the axis of the body, and securing means is provided for selecting the orientation of the axes of these hinges, without changing their retained parallel-axis relation, so as to allow the bolt-holding clamps to rotate in a single plane at a time of predetermined position.
Patent DE-69403242-D1 (DE)
Inventor: KAWAGISHI HIROKAZU
IPC: C12P19/56
Filed: 1994-03-03
Granted: 1997-06-26
Abstract: New cyathane derivatives shown by Formula (1) or (2) given below have the effect of stimulating production of nerve growth factors and antimicrobial effects: <CHEM>   <CHEM> where R is either CHO or CH20H.)
Patent DE-69403573-D1 (DE)
Inventor: LE LANNOU MICHEL
IPC: B29C45/16
Filed: 1994-07-25
Granted: 1997-07-10
Abstract: Method of manufacturing a component by moulding, this component including an internal cavity (5), being in the form of an insert (3) produced in a first thermoplastic (2) covered, at least partially, by a layer of a second, covering thermoplastic (6). According to the invention, a backpressure is provided in the internal cavity (5) when the insert is still malleable during the step of putting the covering material (6) in place. The subject of the invention is also an application of this method to the manufacture of components, such as, in particular, vehicle door handles. <IMAGE>