baber/WOPTO huggingface dataset:
Patent CA-2966568-A1 (CA)
Inventor: WINTER TAL
IPC: B65D41/28
Filed: 2015-10-01
Abstract: A cap for a reusable bottle and a compound-containing container is provided. The container is a separate, replaceable structure with a base (well/bowl) section containing the compound and a hinged or otherwise removable cap. The container is secured in a cavity in the top of the cap using appropriate detents that flex based upon the materials inherent resilient (e.g. a polymer material) to selectively engage with and disengage from the cap cavity. The cap can include a (unitary or integral) hook or ring that extends from the edges of the cap and can provide a stop that the lid of the secured container hinges against when placed in an open position. The hinge includes a detent adjacent to its front edge (opposite the side containing the hinge. This detent retains the lid in a closed position, but can be overcome by pressure applied by the user to open the lid.
Patent CA-2968639-A1 (CA)
Title: Communication-satellite system that causes reduced interference
Inventor: LINDSAY MICHAEL
IPC: H04B7/19
Filed: 2015-11-24
Abstract: A system of low-orbiting communication satellites that can share radio spectrum with geostationary satellites and methods mitigating interference to enable sharing are disclosed. In some embodiments, the satellite progressively tilts as it travels along its orbit, or its transmission beams are mechanically or electronically tilted. As a consequence of the tilting, as a satellite approaches the equatorial plane, its transmission beams are aimed more and more toward the equatorial plane, compared to when the satellite is far from the equatorial plane. Using this technique, an angular separation sufficient to prevent interference between the satellite's radio signals and GEO radio signals at all satellite positions is maintained, and, as a result good coverage is provided to all ground locations.
Patent CA-2972075-A1 (CA)
Inventor: FU JIE
IPC: A61P27/06
Filed: 2015-12-15
Abstract: Methods for increasing the encapsulation or incorporation of Sunitinib into polymeric matrices have been developed. The resulting formulations provide for more sustained controlled release of sunitinib or its analog or a pharmaceutically acceptable salt thereof. Increased loading is achieved using an alkaline solvent system. The pharmaceutical compositions can be administered to treat or prevent a disease or disorder in or on the eye of a patient associated with vascularization, such as corneal neovascularization and acute macular degeneration. Upon administration, the sunitinib or its analog or salt is released over an extended period of time at concentrations which are high enough to produce therapeutic benefit, but low enough to avoid unacceptable levels of cytotoxicity.
Patent CA-2975363-A1 (CA)
Inventor: PATEL JITEN RANCHHODBHAI
IPC: C07J31/00
Filed: 2016-01-30
Abstract: The present invention relates to crystalline forms of S-[4-(3-fluoro-3-methylbutyryloxy)but-2- ynyl] 6a,9a-difluoro- 17a-(furan-2-yl)carbonyloxy- 11ß-hydroxy- 16a-methyl-3-oxoandrosta- 1,4- diene-17ß-carbofhioate, an anti-inflammatory and anti-allergic glucocorticoid compound.
Patent CA-2976132-A1 (CA)
Title: Method for accessing data visitor directory in multi-core system and device
Inventor: GU XIONGLI
IPC: G06F12/08
Filed: 2015-02-16
Abstract: Disclosed are a method for accessing a data visitor directory in a multi-core system, a directory cache device, a multi-core system and a directory storage unit. The method comprises: receiving a first access request sent by a first processor core, the first access request being used for accessing a table entry, corresponding to a first data block, in a directory; determining that a first single-pointer table entry corresponding to the first data block exists in a single-pointer table entry array according to the first access request; and when it is determined that a first shared table entry associated with the first single-pointer table entry exists in a shared table entry array according to the first single-pointer table entry, determining a plurality of visitors of the first data block according to the first shared table entry. The embodiments of the present invention can save storage resources occupied by a directory.
Patent CA-2977763-A1 (CA)
Title: Compressed gas filling method and system
Inventor: GRIMMER ANDY
IPC: F17C13/04
Filed: 2015-11-03
Abstract: A method of filling a storage vessel with a fuel gas at a fuel dispenser. In various embodiments, the method includes providing a fuel dispenser comprising a housing defining a fluid flow path therein, the fluid flow path operatively connected with a source of the fuel gas. The fuel dispenser includes a control valve disposed along the fluid flow path and a controller in operative electronic communication therewith. The method also includes actuating the control valve to provide a predetermined difference between the pressure of the fuel gas upstream of the control valve and the pressure of the fuel gas downstream of the control valve. The predetermined difference is selected such that the temperature of the fuel gas is reduced to a predetermined temperature after passing through the control valve. The method also includes dispensing the fuel gas into the storage vessel, the fuel gas having first mass flow rate.
Patent CA-2977910-A1 (CA)
Inventor: MOGNA GIOVANNI
IPC: A61K31/519
Filed: 2016-03-04
Abstract: The present invention relates to the use of at least one flavonoid of natural or synthetic origin in association with cyclophosphamide and/or methotrexate to increase the effectiveness of chemotherapeutic treatments used in human and veterinary medicine for the treatment of tumors, in particular in case of resistance to the chemotherapeutic agents currently in use; said at least one flavonoid is selected from the group comprising or, alternatively, consisting of rutin, oxerutin, diosmin, troxerutin and hesperidin.
Patent CA-2983113-A1 (CA)
Inventor: VOGLEWEDE BRENDAN
IPC: E21B10/42
Filed: 2015-06-11
Abstract: A drill bit having reinforced binder zones and method of forming same are disclosed. The method includes the steps of mixing reinforcing particles with a binder-reinforcing material, placing the mixture of reinforcing particles and binder-reinforcing material in a mold used in forming a body of the drill bit, placing a universal binder in the mold, and heating the mold. The binder-reinforcing material is infiltrated with the universal binder which thereby forms reinforced binder zones.
Patent CA-2984757-A1 (CA)
Title: Segmentation de donnees operationnelles
Inventor: DAVIDSON MARK J
IPC: G06Q10/06
Filed: 2016-03-14
Abstract: La présente invention concerne des produits programmes informatiques, des procédés, des systèmes, des appareils, et des entités informatiques utilisés pour segmenter des données opérationnelles et identifier des événements d'intérêt dans les données opérationnelles segmentées. Avec les événements d'intérêt identifiés, un temps total entre les événements d'intérêt peut être déterminé.
Patent CA-2986041-A1 (CA)
Title: 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-thioxo-4,5-dihydro-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile compounds as antifungal agents
Inventor: HOEKSTRA WILLIAM J
IPC: C07D401/06
Filed: 2016-05-17
Abstract: The present invention relates to compounds of Formula (I): wherein R1 is as defined herein, or an acceptable salt, solvate, prodrug or hydrate thereof. The compounds of Formula I are inhibitors of metalloenzymes, such as lanosterol demethylase (CYP51 ).
Patent CA-2986865-A1 (CA)
Inventor: GOLDWITZ BRIAN
IPC: A63B63/00
Filed: 2017-11-28
Abstract: Hockey training devices generally include a frame, and a flexible band coupled to the frame. At least one spring may be coupled to at least one longitudinal end of the flexible band. A plurality of backstop structures may be coupled to the frame to extend substantially orthogonal to a top surface of the frame. A first rebounder wing may be coupled to a first side of the frame, and a second rebounder wing may be coupled to a second side of the frame. The first and second rebounder wings may each include a respective wing structure coupled to the frame, and a respective flexible band extending between a portion of the respective wing structure and either the frame or the first flexible band. Other aspects, embodiments, and features are also included.
Patent CA-2987522-A1 (CA)
Title: Dispositif de regulation de la concentration d'un gaz dans un liquide
Inventor: RIGAIL FRANCOIS
IPC: G05D16/20
Filed: 2016-05-27
Abstract: L' invention, concerne un dispositif de régulation (1) de la concentration d'un gaz dans un liquide, le dispositif (1) comprenant une cartouche (2) où se déroule le changement de concentration du gaz dans le liquide, une conduite d'amenée de liquide (3) dans la cartouche (2), une conduite d'amenée de gaz (4) dans la cartouche (2), et une conduite de sortie du liquide (5) hors de la cartouche (2). Selon l' invention, la conduite d'amenée de gaz (4) comprend un détendeur (7) dont la consigne de pression est commandée par une consigne de «quantité du gaz dans le liquide et par une quantité du gaz dans le liquide mesurée par un capteur de concentration du gaz (8) situé dans la conduite de sortie du liquide (5).
Patent CA-2988723-A1 (CA)
Inventor: O'CONNELL JAMES PHILIP
IPC: G01N33/68
Filed: 2015-10-22
Abstract: It has been demonstrated that certain compounds bind to TNF and stabilise a conformation of trimeric TNF that binds to the TNF receptor. Antibodies which selectively bind to complexes of such compounds with TNF superfamily members are disclosed. These antibodies may be used to detect further compounds with the same activity, and as target engagement biomarker.
Patent CA-2989839-A1 (CA)
Title: Modele murin nsg humanise hla-incompatible a xenogreffe derivee de patient
Inventor: KECK JAMES
IPC: A01K67/00
Filed: 2016-06-22
Abstract: L'invention concerne un modèle murin humanisé HLA-incompatible (par exemple, modèle murin NSG) à xénogreffe dérivée de patient (PDX), ainsi que des procédés de production et d'utilisation de celui-ci.<i />
Patent CA-2991690-A1 (CA)
Inventor: REISNER YAIR
IPC: C12N15/85
Filed: 2016-07-14
Abstract: An isolated cell having a central memory T-lymphocyte (Tcm) phenotype, the cell being tolerance-inducing cell and capable of homing to the lymph nodes following transplantation, the cell being transduced to express a cell surface receptor comprising a T cell receptor signaling module is disclosed. Methods of generating same and using same are also disclosed.
Patent CA-2997605-A1 (CA)
Inventor: JOHNSON MICAH
IPC: B65D30/10
Filed: 2018-03-07
Abstract: A bottom gusseted bag includes first and second opposed walls that face one another, each of the first and second walls having an upper end and a lower end, and a gusseted bottom that connects the bottom ends of the first and second walls to one another. The gusseted bottom includes at least four panels that are formed from an open mesh material and that collectively form at least three pleats. Opposed side edges of all of the panels are thermally bonded directly to one another along first and second opposed seams extending at least the majority of the length of each of the panels. The gusseted bottom may have a side seam strength of at least about 1.lb (4.5 N). The first and second side walls are formed at least in part of material, such a film, that is thermally bondable to the mesh material.
Patent CA-3002078-A1 (CA)
Title: Systemes et procedes de gestion de tubes
Inventor: LOCKE CHRISTOPHER
IPC: C12N5/077
Filed: 2016-10-21
Abstract: Des systèmes, des dispositifs et des procédés de la présente invention aident à la gestion de tubes et de tuyaux souples lors d'interventions chirurgicales. Les systèmes, dispositifs et procédés permettent d'assurer l'ouverture et la fermeture appropriées de tubes pour permettre la mise en oeuvre d'étapes lors d'une intervention chirurgicale.
Patent CA-3004366-A1 (CA)
Title: Non-bioconvertible c3-substituted pregnenolone derivatives for use in the treatment of substance use disorders
Inventor: KOOB GEORGE F
IPC: A61P25/32
Filed: 2016-11-04
Abstract: The present invention relates to the use of non-bioconvertible C3-substituted pregnenolone derivatives of pregnenolone and in particular of 33-methoxy-pregna-5-ene-20-one of formula (l):    or a pharmaceutically acceptable salt thereof, with no significant affinity for hormonal receptors or receptors of the central nervous system, in the treatment of substance use disorders, and in particular of alcohol use disorders.
Patent CA-3009342-A1 (CA)
Title: Composes antibacteriens antisens et procedes associes
Inventor: GREENBERG DAVID
IPC: C12N15/113
Filed: 2016-12-22
Abstract: La présente invention concerne des oligomères antisens ciblés contre des ARNm bactériens et d'autres macromolécules associées à une voie biochimique et/ou un processus cellulaire, et des compositions et des procédés associés d'utilisation des oligomères ainsi que des compositions pour traiter un sujet mammifère infecté, par exemple, en tant qu'agents antimicrobiens primaires ou en tant que traitements d'appoint avec des agents antimicrobiens classiques.
Patent CA-3014504-A1 (CA)
Inventor: BEUG SHAWN T
IPC: C07K5/062
Filed: 2017-02-23
Abstract: The present invention includes methods and compositions for enhancing the efficacy of SMCs in the treatment of cancer. In particular, the present invention includes methods and compositions for combination therapies that include an SMC and at least a second agent that stimulates one or more apoptotic or immune pathways. The second agent may be, e.g., an immunostimulatory or immunomodulatory compound or oncolytic virus.
Patent CA-3014988-A1 (CA)
Title: Compositions et procedes de modification de genomes
Inventor: BEGEMANN MATTHEW
IPC: C12N15/82
Filed: 2017-02-15
Abstract: L'invention concerne des compositions et des procédés de modification de séquences d'ADN génomiques. Les procédés produisent des cassures double brin (DSB) au niveau de sites cibles prédéterminés dans une séquence d'ADN génomique, résultant en la mutation, l'insertion et/ou la délétion de séquences d'ADN au niveau du (des) site (s) cible (s) dans un génome. Les compositions comprennent des constructions d'ADN comprenant des séquences nucléotidiques qui codent pour une protéine Cpf1 ou Csm1 liée de manière fonctionnelle à un promoteur qui peut être utilisé dans les cellules d'intérêt. Les constructions d'ADN peuvent être utilisées pour diriger la modification de l'ADN génomique au niveau de loci génomiques prédéterminés. L'invention concerne également des procédés d'utilisation de ces constructions d'ADN pour modifier des séquences d'ADN génomiques. De plus, l'invention concerne des compositions et des procédés de modulation de l'expression de gènes. Les compositions comprennent des constructions d'ADN comprenant un promoteur qui peut être utilisé dans les cellules d'intérêt liées de manière fonctionnelle à des séquences nucléotidiques qui codent pour une protéine Cpf1 ou Csm1 mutée qui n'a plus la capacité de production de DSB, éventuellement liée à un domaine qui régule l'activité transcriptionnelle. Les procédés peuvent être utilisés pour réguler à la hausse ou à la baisse l'expression de gènes au niveau de loci génomiques prédéterminés. 89 CSR 38493285v1 Attorney Docket: B88552 1060WO (0057.1)
Patent CA-3015288-A1 (CA)
Inventor: BEAUCHESNE-MARTEL PHILIPPE
IPC: F01D17/08
Filed: 2018-08-23
Abstract: Herein provided are methods and systems for controlling an engine having a variable geometry mechanism. A pressure ratio between a first pressure at an inlet of the engine and a predetermined reference pressure is determined. An output power for the engine is determined. The output power is adjusted based at least in part on the pressure ratio to obtain a corrected output power. A position control signal for a variable geometry mechanism of the engine is generated based on the corrected output power and the pressure ratio. The position control signal is output to a controller of the engine to control the variable geometry mechanism.
Patent CA-3016654-A1 (CA)
Inventor: GIBSON NATHAN EVAN MCCURDY
IPC: F02C7/28
Filed: 2018-09-06
Abstract: The present disclosure is directed to a gas turbine engine including a turbine rotor, a turbine frame at least partially surrounding the turbine rotor, and an outer diameter seal assembly. The turbine rotor includes an inner shroud, an outer shroud, and at least one connecting airfoil coupling the inner shroud and the outer shroud. The outer shroud includes a plurality of outer shroud airfoils extended inward along a radial direction. The outer diameter seal assembly' includes a sliding portion disposed between the turbine frame and the outer shroud of the turbine rotor. The outer diameter seal assembly defines a secondary tooth at the outer shroud radially inward of a longitudinal face of the sliding portion, and a primary tooth defined axially adjacent to a radial face of the sliding portion.
Patent CA-3020288-A1 (CA)
Inventor: BERTHALON SYLVAIN
IPC: B64C27/605
Filed: 2018-10-09
Abstract: La présente invention concerne un rotor à pas collectif variable (1) mobile en rotation autour d'un axe de rotation (AXROT). Ledit rotor à pas collectif variable comprend une pluralité de pales (15). Un mécanisme de man uvre comprend une tige de commande (31) montée mobile en translation par rapport au moyeu (10) et un plateau de commande (40) monté tournant sur la tige de commande (31). Des bielles de pas (60) sont articulées au plateau de commande (40) et à des leviers de pas (18) des pales (15). Le mécanisme de man uvre comporte un tube de positionnement angulaire (80) solidaire en rotation et en translation du plateau de commande (40). Le moyeu (10) et le tube de positionnement angulaire (80) sont liés par une liaison combinée (83) qui induit une rotation autour de l'axe de rotation (AXROT) dudit tube de positionnement angulaire (80) et dudit plateau de commande (40) par rapport au moyeu (10) lors d'une translation du tube de positionnement angulaire (80).
Patent CA-3020293-A1 (CA)
Inventor: LETTON ANDREW MARTIN
IPC: A61M16/16
Filed: 2017-04-27
Abstract: A humidification chamber (24, 50, 300, 400, 500, 600 or 700) for humidifying gases is provided comprising: a water tub that is configured to receive a volume of water; a gases inlet for receiving a flow of gases into an interior volume of the humidification chamber; and a gases outlet through which a humidified flow of gases may exit the interior volume of the humidification chamber. One or more fill apertures (120) are provided in fluid communication with the water tub such that the water tub can be filled with water through the one or more fill apertures. A sealing closure (850) is also provided and configured to be releaseably mounted on the humidification chamber (24, 50, 300, 400, 500, 600 or 700), the sealing closure (850) being configured to sealingly close each fill aperture (120) when the sealing closure (850) is mounted on the humidification chamber to resist gas and/or vapour escaping from the one or more fill apertures (120).
Patent CA-3021282-A1 (CA)
Inventor: ENDRES STEVEN P
IPC: G06F17/00
Filed: 2018-10-18
Abstract: Embodiments of the disclosed technology involve an integration system configured to integrate disparate data sources retrieved from an air traffic server and a ticket vendor server. An air traffic server and a ticket vendor server can be iteratively queried. An integrated dataset can be generated by identifying segment associated with a slot and mapping the identified segments. A congestion delay can be determined based on the integrated dataset. A congestion delay target based on an estimated time value of a plurality of passengers may be selected by identifying a convergence between an estimated yield loss from reducing the number of flights and the estimated value of time for the plurality of passengers. A utilization level of the slot may be determined based on the selected congestion delay target.
Patent CA-3022772-A1 (CA)
Title: Recipient pour produits fluides, en particulier pour produits medicaux, pharmaceutiques, cosmetiques, aliments ou similaire
Inventor: SALVARANI ENRICO
IPC: A61J1/06
Filed: 2017-05-18
Abstract: La présente invention concerne un récipient (1) pour des produits fluides, en particulier pour des produits médicaux, pharmaceutiques, cosmétiques, des aliments ou similaire, qui comprend : - un corps creux (2) pour le confinement d'un produit fluide comportant un col (3); - un élément de fermeture (8) comportant une partie de fixation (9) qui, dans une configuration de fermeture, est associée au corps creux (2) le long d'une ligne de rupture prédéfinie (10) adaptée pour permettre la séparation de l'élément de fermeture (8) du corps creux (2) dans une configuration de séparation dans laquelle, sur le corps creux (2), est formée une ouverture pour la sortie du produit fluide; - au moins un élément de rabat (11) pour supporter des informations, des données ou des logos (12), assemblé à la partie de fixation (9) et mobile entre une configuration initiale dans laquelle l'élément de rabat (11) est éloigné du col (3), et une configuration finale dans laquelle l'élément de rabat (11) est ajusté au moins partiellement autour du cou (3) pour former une clé de manuvre (13) adaptée pour permettre le retrait par déchirement de l'élément de fermeture (8).
Patent CA-3024940-A1 (CA)
Title: De-icing apparatus
Inventor: CHAUVET LOUIS
IPC: F02C7/047
Filed: 2018-11-21
Abstract: A de-icing apparatus configured to remove ice from a surface part of an aircraft, the de-icing apparatus comprising a heating layer and a conductive surface extending over, and in heat conductive contact with, the heating layer, the conductive surface defining at least a part of the surface part of the aircraft or an aircraft component;  the heating layer comprising heating elements defining substantially closed contour zones, each comprising a periphery formed by the heating elements within which an area is defined; the heating layer and the conductive surface configured such that when power is provided to the apparatus the heating elements which fragment ice formed on the surface part of the aircraft according to the shape of the peripheries of the substantially closed contour zones, and wherein on continued application of power, heat from the heating elements then spreads into the areas within the peripheries of the substantially closed contour zones due to conduction of heat from the heating elements through the leading edge.
Patent CA-3025660-A1 (CA)
Inventor: SHINOHARA YUJI
IPC: B65D77/04
Filed: 2017-03-31
Abstract: The present invention can eliminate the inconvenience of unfolding a wet sheet after it is taken out and thus can improve the convenience in using the wet sheet. A layered body (3) of folded wet sheets is stored in an exterior bag (8) having an outer taking-out opening (23), which can be opened and closed by an opening sealing means (24), provided on the upper-surface side. The layered body (3) is stored in such a manner that the wet sheet at the top can be taken out while being unfolded by picking an edge section (19) on the upper-surface side. The layered body (3) is formed of a plurality of wet sheets that are folded in a zigzag manner to make a band-like folded body, and the edge section (19) is located at the widthwise middle section of the folded body so as to extend in the longitudinal direction.
Patent CA-3026025-A1 (CA)
Inventor: NAKAO SHINSUKE
IPC: A61P35/02
Filed: 2017-05-29
Abstract: [Technical Problem] The present invention provides a genetically recombinant vaccinia virus effective in preventing or treating cancer. [Solution to Problem]      Specifically, the present invention provides a vaccinia virus comprising two polynucleotides, a polynucleotide encoding IL-7 and a polynucleotide encoding IL-12; a combination kit of two vaccinia viruses, a vaccinia virus comprising a polynucleotide encoding IL-7 and a vaccinia virus comprising a polynucleotide encoding IL-12; and use of the two vaccinia viruses in combination.