baber/WOPTO huggingface dataset:
Patent CA-2273888-C (CA)
Title: Sealless pump rotor position and bearing monitor
Inventor: IMLACH JOSEPH
IPC: G01M13/04
Filed: 1997-12-05
Granted: 2006-10-03
Abstract: A bearing monitor for use with a canned motor pump having a wound stator and a rotor drivably coupled to an impeller, the rotor being mounted on radial journal bearings and axial thrust bearings within a containment can comprises a first and a second target embedded in an outer periphery of the rotor in axial proximity to a first and a second end of the rotor. The monitor includes a plurality of sensors mounted external to the containment can in axial proximity to each of the two targets and radially displaced approximately equally around the periphery of the containment can. A plurality of magnetic field generators create local magnetic fields coupled through the containment can, process fluid, rotor, and at least a portion of one target to one of the sensors. In response to each field, each sensor generates an output signal which varies as a result in a change in the magnetic circuit reluctance caused by bearing wear. A monitor circuit is coupled to the sensors and compares their output signals to generate a scaled output which is approximately linearly related to bearing wear. The output of sensors in the same axial plane are utilized to determine bearing wear in a radial direction, while the output of sensors in different axial planes are utilized to determine bearing wear in an axial direction.  Electromagnetic shielding may be used depending on the environmental and operating conditions.
Patent CA-2274116-C (CA)
Title: Use, of an inhibitor of thioredoxin, for inhibiting tumor growth
Inventor: POWIS GARTH
IPC: A61K38/44
Filed: 1997-12-05
Granted: 2009-05-05
Abstract: The present invention re]ates to the use of thioredoxin as, inter alia, a cell growth stimulator, as well as a screen for agents that are useful in reducing or preventing thioredoxin-associated apoptosis inhibition and agents that are useful in inhibiting thioredoxin stimulated cell growth.
Patent CA-2283292-C (CA)
Title: Hydrolytically stable resins for use in anion-exchange chromatography
Inventor: POHL CHRISTOPHER
IPC: B01D15/04
Filed: 1998-03-03
Granted: 2008-10-14
Abstract: In accordance with the present invention, an improved anion-exchange chromatographic composition has been formed which comprises synthetic resin support particles and anion exchange compounds attached thereto, wherein the anion-exchange compounds comprise an internal reactive group, which may be an ester, ketone or amide group, and a terminal quaternary ammonium salt which functions as an anion-exchange site. The compositions of the present invention exhibit improved hydrolytic stability as compared to other known anion-exchange chromatographic compositions due to the presence of linkers which increase the number of atoms separating the internal reactive group form the nitrogen atom of the terminal ammonium anion-exchange site. Formed articles and methods employing the anion-exchange chromatographic composition are also provided.
Patent CA-2284690-C (CA)
Inventor: STEELE JACK W
IPC: B23B31/20
Filed: 1998-04-03
Granted: 2005-10-25
Abstract: A sealed collet having improved radial flexibility is provided for facilitating removal from a locknut of a chuck assembly. The sealed collet includes a collet body formed from a tubular configuration of elongated gripping fingers separated by elongated slots which render the body radially resilient in response to pressure applied by a locknut. The slots are filled with a bonding agent, which may be a silicon rubber compound, for preventing dirt and debris from entering the collet slots and for preventing pressurized coolant intended to flow through a bore in a tool shank from flowing through the walls of the collet body. To increase the radial compressibility of the collet, agent-free gaps are provided in the slots immediately behind a distal portion of the collet body. In the preferred embodiment, the length of the agent-free gap is between 20 % and 30 % of the overall length of its respective slot. The location of the gaps immediately behind the distal end of the collet body advantageously increases the radial compressibility of the collet while allowing the bonding agent in the slots to continue to prevent debris from entering the collet.
Patent CA-2285573-C (CA)
Inventor: HIRSCHMAN SHALOM Z
IPC: A61K31/70
Filed: 1998-04-15
Granted: 2008-09-30
Abstract: Cette invention se rapporte à un procédé permettant de traiter l'anémie par stimulation de la production des globules rouges du sang, ce procédé consistant à administrer par voie parentérale un produit R, qui est une préparation de peptides et d'acides nucléiques.
Patent CA-2286368-C (CA)
Title: Balais a laver
Inventor: CARLSON ARTHUR RICHARD
IPC: F16B7/18
Filed: 1998-03-27
Granted: 2006-06-13
Abstract: L'invention concerne un balai à laver comprenant un manche allongé (3) et une tête (5), qui porte un matériau pour laver comportant une garniture de type éponge que l'on peut presser (13). Le balai comporte un système de bras (27, 29, 37, 39), que l'on peut déplacer afin de presser le matériau pour laver (13), et un raccord pivotant (7) avec deux axes perpendiculaires (57, 59). Selon la structure, la tête (5) du balai peut pivoter de façon à prendre diverses orientations angulaires par rapport au manche (3), et le balai comporte un raccord pivotant à deux axes et un système permettant de presser le matériau pour laver (13). La tête comporte des bandes de renforcement qui résistent au mouvement de torsion quand on presse le matériau pour laver. Le raccord pivotant (7) comprend une partie plane (73) qui comporte une tige pivot (77) définissant un axe (57), ainsi qu'un orifice central (75) définissant un autre axe (59). L'axe (59) est lui-même représenté par une tige pivot (101) disposée sur une autre partie (99). La partie (99) peut s'apparier avec une autre partie (85). Les parties (85) et (99) forment un corps tubulaire présentant un filetage interne. Un collier (89) peut être placé sur les surfaces externes du corps tubulaire présentant le filetage (87). Quand le manche (3) est vissé dans le filetage du corps, il écarte radialement ce dernier et tend à le pousser en contact serré avec le collier (89), ce qui maintient l'ensemble.
Patent CA-2290600-C (CA)
Inventor: MOWER MORTON M
IPC: A61B/
Filed: 1998-07-02
Granted: 2002-09-03
Abstract: Augmentation of electrical conduction and contractility by biphasic cardiac pacing. A first stimulation phase is administered to the muscle tissue. This first stimulation phase has a predefined polarity, amplitude and duration. A second stimulation phase is then administered to the muscle tissue. This second phase also has a predefined polarity, amplitu de and duration. The two phases are applied sequentially. Contrary to current thought, anodal stimulation is first applied, followed by cathodal stimulation. In this fashion, pulse conduction  through the cardiac muscle is improved together with an increase in contractility. The technique  can also be applied to large muscle tissue stimulation other than cardiac muscle.
Patent CA-2297221-C (CA)
Title: Endoscope with reusable core and disposable sheath with passageways
Inventor: ADAIR EDWIN L
IPC: A61B1/00
Filed: 1998-07-28
Granted: 2001-11-27
Abstract: An endoscope in one configuration includes an elongated cylindrical core with a transparent window at the distal end thereof. A removable housing is placed within the core along with an objective endoscope lens or optics at the distal end thereof. A photosensitive image sensor is mounted within the core. A transmitting electronic means with multiple conductors each has a distal end connected to the image sensor circuit board or image sensor and a proximal end connected to a video control unit. From the video control unit signals are transmitted to the video monitor which displays the image. A separable and disposable sheath or channel section is provided in a sterile condition and removably receives the core in a defined relationship. The sheath has at least one longitudinal channel formed around its periphery for transmitting fluids or for receiving an operative instrument or carrying light transmitting fibers. A flexible tube is connected to the proximal end of the sheath for supplying fluid or for manipulating the operative instrument from a remote location. The sheath is disposable after use on a patient and the core is prepared for reuse with another sheath on the next patient. In a second configuration, an ultrasound transducer is placed through the core after a first visual image of the desired area has been taken by the image sensor. The core is open at the distal end to permit the transducer to extend beyond it during use.
Patent CA-2302162-C (CA)
Title: Fast-detaching electrically insulated implant
Inventor: BASHIRI MEHRAN
IPC: A61F2/90
Filed: 1998-08-27
Granted: 2008-09-23
Abstract: This is an implant for placement in the human body and an assembly for so placing that implant. Most desirably, it is an implant for use in the vasculature of the human body and is used to occlude some space in that vasculature as a portion of a treatment regimen.  The implant itself is preferably a component of a deployment device using an electrolytically severable joint. The implant component is at least partially covered with a highly resistive or insulative covering. The highly resistive or insulative layer or covering appears to enhance the susceptibility of the electrolytic joint to quick erosion and thus detachment of the implant. Although the implant itself is preferably a vaso-occlusive device, it may instead be a stent, a vena cava filter, or other implant which may be installed in this manner. The implant may be independently coated with insulative or resistive material or may be formed using a material such as tantalum, which forms such an insulator or resistor in situ.
Patent CA-2304207-C (CA)
Title: Rna export element and methods of use
Inventor: HOPE THOMAS J
IPC: C12N15/86
Filed: 1998-09-17
Granted: 2012-03-20
Abstract: A cis-acting posttranscriptional regulatory element (PRE) useful for efficient RNA export of RNA is provided. The element, termed WPRE, is originally derived from woodchuck hepatitis virus. The invention also provides a method for enhancing the expression of transgenes by insertion of the WPRE nucleic acid sequences in operably linkage with the transgene.
Patent CA-2304645-C (CA)
Inventor: BENSON SCOTT CONRAD
IPC: C07H21/00
Filed: 1998-09-18
Granted: 2008-08-26
Abstract: A invention concerne une classe de composés à base de xanthène à substitution aromatique utiles en tant que colorants fluorescents, lesquels composés présentent une structure générale (I), dans laquelle Y1 et Y2, pris séparément, sont sélectionnés dans le groupe constitué par hydroxyle, oxygène, imminium, groupe de liaison et amine, ou Y1, pris avec R2, représente imine cyclique, ou Y2, pris avec R3, représente amine cyclique; R2, R3, R5 et R7, pris séparément, sont sélectionnés dans le groupe constitué par hydrogène, fluor, chlore, alkyle inférieur, alcène inférieur, alcyne inférieur, sulfonate, sulfone, amino, imminium, amido, nitrile, alcoxy inférieur, phényle et groupe de liaison; R1, pris séparément, est sélectionné dans le groupe constitué par phényle, phényle substitué, aromatique polycyclique, aromatique polycyclique substitué, groupe de liaison, et hétérocycle riche en électrons, ou, lorsqu'il est pris avec R7, est sélectionné dans le groupe constitué par hétérocycle riche en électrons et indène; R4, pris séparément, est sélectionné dans le groupe constitué par amino, amido, phényle, phényle substitué, aromatique polycyclique, aromatique polycyclique substitué, indène, groupe de liaison et hétérocycle riche en électrons, ou, lorsqu'il est pris avec R5, est sélectionné dans le groupe constitué par phényle, phényle substitué, aromatique polycyclique, aromatique polycyclique substitué, indène et hétérocycle riche en électrons; et R6 est sélectionné dans le groupe constitué par acétylène, alkyle inférieur, alcène inférieur, cyano, phényle, phényle substitué et aromatique hétérocyclique. Dans un deuxième aspect, l'invention concerne des procédés de synthèse de ces composés de colorant et de leurs intermédiaires. Dans un troisième aspect, la présente invention concerne des réactifs marqués avec ces composés de colorant à base de benzoxanthène asymétrique, y compris des désoxynucléotides, des didésoxynucléotides, des phosphoramidites et des polynucléotides. Dans un quatrième aspect, l'invention concerne des procédés utilisant ces composés de colorant et ces réactifs, notamment des procédés de séquençage de polynucléotides didésoxy et d'analyse de fragments.
Patent CA-2305760-C (CA)
Inventor: FURNEAUX RICHARD HUBERT
IPC: A01N43/04
Filed: 1998-10-14
Granted: 2008-06-03
Abstract: L'invention porte: sur des composés de formule (I) dans laquelle: A est CH ou N; B est choisi parmi OH, NH2, NHR, H ou halogène; D est choisi parmi OH, NH2, NHR, H, halogène ou SCH3; R est alkyle, aralkyle ou aryle facultativement substitués; et X et Y sont choisis indépendamment parmi OH, H ou halogène sous réserve que si l'un d'eux est halogène, l'autre soit H; et Z est OH ou si X est hydroxy, Z est OH ou, si X est hydroxy, z est choisi parmi H, halogène, hydroxy, SQ ou OQ (Q étant alkyle, aralkyle ou aryle facultativement substitués); ou sur un de leurs tautomères, ou sels pharmacocompatibles, ou esters, ou bioprécurseurs. L'invention porte également sur des composés de formule (Ia) dans laquelle: A, X, Y, Z et R sont définis comme ci-dessus; E est choisi parmi CO2H ou une forme de sel correspondante, CO2R, CN, CONH2, CONHR, ou CONR2; et G est choisi parmi NH2, NHCOR, NHCONHR ou NHCSNHR, ou sur un de leurs tautomères, ou sels pharmacocompatibles, ou esters, ou bioprécurseurs. L'invention porte en outre sur l'utilisation desdits composés sous forme de produits et préparations pharmaceutiques les contenant, et sur leurs procédés de préparation.
Patent CA-2306016-C (CA)
Inventor: LILLICO DOUGLAS A
IPC: E21B33/124
Filed: 2000-04-18
Granted: 2004-11-23
Abstract: A method and an apparatus for injecting a fluid into a borehole. The method includes the step of injecting an injection fluid into a primary injection zone in a borehole at an injection fluid pressure. The primary injection zone is bounded by a proximal injection zone interface and a distal injection zone interface. The proximal injection zone interface and the distal injection zone interface are maintained at pressures which are substantially balanced with the injection fluid pressure.  The apparatus includes a body adapted for passage through a borehole, at least four radially extendable and retractable zone interface elements spaced longitudinally along the body which when extended define at least three zones along the body, a zone interface element actuator for selectively extending and retracting the zone interface elements, and a fluid delivery system for delivering a fluid to each zone. The central zone defined by the zone interface elements is the primary injection zone and the zones on either side of the primary injection zone are balancing zones which are used to achieve substantial pressure balancing with the fluid injection pressure at the proximal injection zone interface and the distal injection zone interface.
Patent CA-2306449-C (CA)
Title: Rapid generation of stable mammalian cell lines producing high levels of recombinant proteins
Inventor: MCCOY JOHN
IPC: C07K14/035
Filed: 1998-10-21
Granted: 2008-12-16
Abstract: Disclosed are methods, DNA sequences, vectors and cell lines useful for the rapid generation of stable mammalian cell lines expressing high levels of recombinant proteins.
Patent CA-2307545-C (CA)
Inventor: OGURI TOSHITAKA
IPC: H04B17/00
Filed: 2000-05-04
Granted: 2005-01-18
Abstract: First and second supervised cards 103 and 104 are respectively provided with bus registers 114 and 115, CPUs 116 and 117 detect occurrence of a state change or failure of the respective apparatuses, the detected state change or failure information is stored in bus registers 114 and 115, and CPU 110 of currently used supervising card 101, alternately set to be used or reserved, reads the stored state change or failure information through supervisory control bus 105, and thereby supervises first and second supervised cards 103 and 104.
Patent CA-2314145-C (CA)
Title: Electrical connector
Inventor: MCCARTHY DALE C
IPC: H01R13/59
Filed: 1998-06-11
Granted: 2005-12-20
Abstract: An electrical connector (10) for coupling to a plurality of insulated electrical conductors (28, 30) has a housing (11) and a housing cover both having a plurality of bores therein, at least a portion of each bore being tapered. A plurality of electrical conductive prongs each having one end attached to the housing and extending axially into each housing bore for receiving the end of an insulated electrical conductor.  Attaching means attach the housing cover to the housing over a plurality of compression collars. Each compression collar has a bore extending axially therethrough to allow for insertion of a wire therethrough and into the housing bore and onto a pointed prong.
Patent CA-2322527-C (CA)
Inventor: HARRISON NIGEL DAVID
IPC: B65D51/22
Filed: 1999-02-17
Granted: 2007-04-10
Abstract: A plastics pour spout fitment (3) has not only a pour spout (4) thereof weld ed to plastics-coated paperboard packaging material (2), but also has a plunger (14) welded to a disc (8) of the material (2), the disc (8) being defined by a ring of weakening (6) i n the material. Following purely linearly axially inward displacement of the plunger (14) relative to the pour spout (4), preferably followed by rotation of the plunger (14) about the axi s A of the fitment (3) relative to the spout (4), to detach the disc (8) from the remainder of the material (2), the plunger (14), and thus the disc (8), are removed from the pour spout (4) as a screw cap (12) is removed from the spout (4).
Patent CA-2323540-C (CA)
Inventor: KORTENBACH JUERGEN A
IPC: A61B17/06
Filed: 1999-03-19
Granted: 2004-12-07
Abstract: A surgical instrument for applying sutures to tissue includes a needle deployment mechanism (127) and a catch mechanism (129). In some embodiments, the needle deployment mechanism (127) employs a linear path. Alternatively, it can employ a curved needle. The surgical instrument may include a rotatable head (124), a bend (122), and/or a malleable elongated body member formable into various shapes.
Patent CA-2323687-C (CA)
Title: Mutant recombinant allergens
Inventor: IPSEN HANS HENRIK
IPC: C07K14/415
Filed: 1999-03-16
Granted: 2008-11-25
Abstract: Novel recombinant allergens are disclosed. The allergens are non-naturally occuring mutants derived from naturally-occurring allergens. The overall .alpha.-carbon backbone tertiary structure is essentially preserved. Also disclosed are methods for preparing such recombinant allergens as well as uses thereof.
Patent CA-2326283-C (CA)
Title: Brassica napus with early maturity (early napus) and resistance to an ahas-inhibitor herbicide
Inventor: CHARNE DAVID
IPC: A01H5/10
Filed: 2000-11-17
Granted: 2008-04-29
Abstract: Improved varieties of Brassica napus having early maturity ("Early Napus") and resistance to an AHAS-inhibitor herbicide, such as an imidazolinone, are provided. These varieties may be used to produce inbreds or hybrids or to produce vegetable oil and meal. Parts of these plants, including plant cells, are also provided.
Patent CA-2337002-C (CA)
Inventor: KALIAGUINE SERGE
IPC: C01G51/00
Filed: 1999-07-15
Granted: 2009-02-10
Abstract: La présente invention concerne des oxydes métalliques présentant une structure cristalline perovskite ou de type perovskite, préparés par un procédé consistant à soumettre un mélange de poudres de départ à un broyage haute puissance suffisant pour induire la réaction chimique des composants, et procéder ainsi à la mécano-synthèse dudit oxyde métallique pour obtenir un matériau perovskite ou de type perovskite, présentant une structure nanocristalline telle que déterminée par la méthode de mesure par diffraction des rayons X. Le procédé de cette invention qui est simple, efficace et peu coûteux, ne nécessite pas d'étape de chauffage pour produire un perovskite pouvant facilement présenter une surface spécifique très haute. L'autre avantage de ce procédé est que le perovskite obtenu présente également une haute densité de défauts du milieu moléculaire, qui est la preuve d'une importante activité catalytique; laquelle activité constitue une propriété indispensable lors de son éventuelle application comme catalyseurs et comme conducteurs électroniques.
Patent CA-2338632-C (CA)
Title: Teeth crevice cleaning apparatus and method of using the same
Inventor: CHEN SHUQI
IPC: A61C17/00
Filed: 1999-07-23
Granted: 2008-02-12
Abstract: A mouth pad (2) for cleaning teeth crevices has a U-shaped plate (1) sized to cover substantially only the biting surfaces of upper and lower teeth of a human jaw. The plate (1) is positioned between the upper teeth and lower teeth such that when the teeth are rinsed with a liquid, the liquid flows primarily through the crevices between individual teeth, and physically detaches the adhering residue within. A method of cleaning teeth using a plate (1) positioned between the upper, and lower teeth is also disclosed.
Patent CA-2348522-C (CA)
Inventor: BRITS WILLEM HENDRIK
IPC: C22B9/02
Filed: 1999-10-29
Granted: 2009-07-28
Abstract: This invention relates to a method for assaying an ore sample to determine the concentration of gold and PGMs therein. The method comprises the steps of preparing an ore sample, combining the prepared ore sample with a lead-containing flux, inductively heating the combination (typically at a predetermined reference temperature profile) to form a fusion of slag and lead containing the gold and PGM's in the sample and separating the lead from the slag. The invention also covers a new flux for the process, the flux containing sodium hydroxide, a container for mixing the flux and an ore sample and an apparatus for separating molten lead from slag.
Patent CA-2353554-C (CA)
Title: Derives bacteriochlorophylle a substitution palladium et utilisation associee
Inventor: SCHERZ AVIGDOR
IPC: A61P31/12
Filed: 1999-12-09
Granted: 2011-04-26
Abstract: L'invention concerne des dérivés bactériochlorophylle à substitution palladium, correspondant à la formule (I) dans laquelle A représente OH, OR¿1?,O-(CH¿2?)¿n?-Y,S-(CH¿2?)¿n?-Y,NH-(CH¿2?)¿n?-Y,O-(CH¿2?)¿2?-NH¿2?,O-(CH¿2?)¿2?-OH,NH-(CH¿2?)¿n?- ?+¿N o, X?-¿,NH-(CH¿2?)¿2?-NH=BOC ouN-(CH¿2?-CH=CH¿2?)¿2?, où R¿1? représente Na?+¿, K?+¿, (Ca?2+¿)¿0,5,? (Mg?2+¿)¿0,5?, Li?+¿, NH¿4??+¿, ?+¿NH¿3?-C(CH¿2?OH)¿3?, ?+¿NH¿3?-CH¿2?-(CHOH)¿4?-CH¿2?OH, ?+¿NH¿2?(CH¿3?)-CH¿2?-(CHOH)¿4?-CH¿2?OH or ?+¿N(C¿n'?H¿2n'+1?)¿4?, R¿2? représente H, OH or COOR¿4?, où R¿4? représente alkyle C¿1?-C¿12? ou cycloalkyle C¿3?-C¿12?, R¿3? représente H, OH ou alkyle ou alcoxy C¿1?-C¿12?; n vaut 1, 2, 3, 4, 5 ou 6, Y représenteNR'¿1?R'¿2? ou?+¿NR'¿1?R'¿2?R'¿3?, X?-¿ où R'¿1?, R'¿2? et R'¿3? représentent chacun indépendammentCH¿3? ouC¿2?H¿5?; X représente F, Cl, Br ou l, n' vaut 1, 2, 3 ou 4. L'invention concerne également des formes oxydées de ces dérivés. Ces dérivés et leurs formes oxydées sont utiles dans le domaine de la thérapie photodynamique (TPD).