baber/WOPTO huggingface dataset:
Patent JP-2017091408-A (JP)
Title: Drive support apparatus
Inventor: YAMASHITA TAKASHI
IPC: G08G1/09
Filed: 2015-11-16
Abstract: PROBLEM TO BE SOLVED: To suppress discomfort caused to the driver of a following vehicle.SOLUTION: A drive support apparatus 100 includes a vehicular speed sensor 16, a GPS receiver 14, a signal information receiver 12, a following vehicle information receiver 20, and an ECU 30. Following vehicle information received by the following vehicle information receiver 20 contains first information and second information, where the former is related to whether a following vehicle 3 is capable of executing performance related to a following vehicle deceleration support while the latter is related to a present travel mode of the following vehicle 3. The ECU 30 determines whether a deceleration support execution condition is met and executes an own-vehicle deceleration support in the case of the aforementioned condition being met. Even in the case of the deceleration support execution condition being met, the ECU 30 executes no own-vehicle deceleration support in a case where the ECU determines that the following vehicle 3 is incapable of executing the following vehicle deceleration support on the basis of the first information, and that a travel mode of the following vehicle 3 is a sports mode or none of the sports mode and eco-mode on the basis of the second information.SELECTED DRAWING: Figure 1
Patent JP-2017094610-A (JP)
Title: Electrical apparatus
Inventor: FUKUDA MOTOYUKI
IPC: B41J29/00
Filed: 2015-11-25
Abstract: PROBLEM TO BE SOLVED: To provide an electrical apparatus that can sufficiently inhibit an erroneous operation of a power switch.SOLUTION: An image formation device (an electrical apparatus) 100 includes: a recessed part 12 provided at a right-side face 11 and having a front face-side inclination face 12a inclined relative to the right-side face 11 and directing on a back face side; and the power switch 13 provided at the front face-side inclination face 12a so as not to project on an outside relative to the right-side face 11.SELECTED DRAWING: Figure 2
Patent JP-2017093997-A (JP)
Title: Method for measuring electrocardiogram, and clothes for measuring electrocardiogram
Inventor: SHIOZAWA SHIGEHIRO
IPC: A61B5/0478
Filed: 2015-11-27
Abstract: PROBLEM TO BE SOLVED: To provide a method for measuring an electrocardiogram with reduced noise, and clothes for measuring the electrocardiogram capable of measuring such the electrocardiogram.SOLUTION: A method is provided for measuring an electrocardiogram of a human body. The method is characterized by measuring the electrocardiogram as follows: a first sensor is brought into abutment with any position in an area surrounded by a central line of a breastbone of a human body front side, a left front axillary line, the fifth rib upper end, and the eighth rib lower end; a second sensor is brought into abutment with any position in the area surrounded by the central line of the breastbone of the human body front side, a right front axillary line, the fifth rib upper end, and the eighth rib lower end; and a third sensor is brought into abutment on a perpendicular when drawing the perpendicular relative to the line for connecting the first sensor center and the second sensor center from the center point of the line for connecting the first sensor center and the second sensor center toward the head direction of the human body.SELECTED DRAWING: Figure 2
Patent JP-2017100747-A (JP)
Title: Double container
Inventor: FURUSAWA MITSUO
IPC: B65D1/02
Filed: 2015-11-30
Abstract: PROBLEM TO BE SOLVED: To prevent blowout of a content from a bung hole resulting from elevation of atmospheric temperature in a double container having an outdoor air introduction hole on a bottom part.SOLUTION: A double container 1 comprises: an outer layer body 2 forming a bottle shape having a mouth part 4, a trunk part 6 and a bottom part 7, and having an outdoor air introduction hole 11 penetrating the bottom part 7 therein in an inward/outward direction; a freely volume reduction-deformable inner layer body 3 having a content-filling space M and stored inside the outer layer body 2; a pouring plug 16 which is loaded to the mouth part 4 and in which a bung hole for pouring out a content stored in the filling space is provided; and a lid body 17 freely opening or closing the bung hole. A longitudinal rib-like outer layer rib 8 is provided to the trunk part 6 of the outer layer body 2.SELECTED DRAWING: Figure 1
Patent JP-2017101730-A (JP)
Title: Bearing device
Inventor: KANEKO SHOTARO
IPC: F16C33/62
Filed: 2015-12-01
Abstract: PROBLEM TO BE SOLVED: To provide a bearing device which can be used in a proper state regardless of a use environmental temperature.SOLUTION: A rolling bearing 13 has: a housing 11; a shaft 12; an inner ring 14 fitting on the shaft 12; an outer ring 15 fitted in the housing 11; and rolling elements 16 which are disposed between the inner ring 14 and the outer ring 15 so as to roll. A material of the housing 11 has a heat expansion coefficient larger than that of the outer ring 15 forming the bearing 13. An axial cross section of an inner peripheral surface of the housing 11 is a non-perfect circle shape.SELECTED DRAWING: Figure 1
Patent JP-2017103114-A (JP)
Title: High-frequency irradiation device, high-frequency irradiation system, and high-frequency irradiation method
Inventor: TSURU MASAOMI
IPC: H05B6/66
Filed: 2015-12-02
Abstract: PROBLEM TO BE SOLVED: To provide a high-frequency irradiation device, a high-frequency irradiation system and a high-frequency irradiation method, in which heating of an object to be heated can be efficiently performed even when physical property change of the object to be heated due to heating occurs.SOLUTION: In a high frequency irradiation device, the input power inputted when output of an oscillator (2) generating a high frequency is detected, output frequency of the oscillator (2) is controlled in accordance with the detection result, the frequency variation amount per unit time of the output frequency of the controlled oscillator (2) is detected, and output phase of the oscillator (2) is controlled in accordance with the detection result.SELECTED DRAWING: Figure 1
Patent JP-2017101490-A (JP)
Title: Fixture
Inventor: TSUTSUI HANA
IPC: E06B1/18
Filed: 2015-12-03
Abstract: PROBLEM TO BE SOLVED: To suppress outdoor-indoor heat transmission while keeping a fire retardant property.SOLUTION: Two frame elements 15A, 15B are adjacently installed in depth direction so as not to contact to each other. In a fixture, a mullion frame 15 is formed by connecting the two frame elements, 15A, 15B via a heat insulator 15C so that a hollow part 15D is formed between them. An expansive member 40 is molded using a material including a thermal expansive member, which expands when heated, and the expansive member 40 is inserted in the hollow part 15D along longer direction so that the hollow part 15D becomes an expansive space.SELECTED DRAWING: Figure 3
Patent JP-2017104148-A (JP)
Title: Water flow detector
Inventor: HATAKEYAMA TAKAO
IPC: A62C35/68
Filed: 2015-12-07
Abstract: PROBLEM TO BE SOLVED: To provide a water flow detector that prevents a state in which an electric path is blocked from being left as it is when performing the stopping of signal output from a limit switch for detecting an opening operation of a valve body by an operation of an electric switch in sprinkler equipment.SOLUTION: In a water flow detector that has a valve body of a check valve structure in a hollow body, and includes a limit switch 3 actuated by the opening of the valve body, a switch 4 for opening and closing an electric path is installed in the electric path for transmitting a signal to a reception panel from the limit switch 3, and an output device 5 for issuing a signal in a state in which the electric path is blocked by the switch 4 is installed.SELECTED DRAWING: Figure 3
Patent JP-2016095517-A (JP)
Title: Display device
Inventor: KIM HYUK-JIN
IPC: G02F1/133
Filed: 2015-12-15
Abstract: PROBLEM TO BE SOLVED: To provide a liquid crystal display device which improves visibility and transmittance.SOLUTION: A liquid crystal display device comprises: a first substrate including a first electric field forming electrode including a plurality of sub-electrodes arranged in parallel with each other away at a prescribed interval within a pixel area and a connection electrode for electrically connecting the respective sub-electrodes and a first alignment film rubbed in a first direction of covering the first electric field forming electrode; or a second substrate including a second electric field forming electrode including a plurality of openings formed in parallel with each other in an area corresponding to the pixel area of the first substrate and a second alignment film rubbed in a second direction of covering the second electric field forming electrode.SELECTED DRAWING: Figure 1
Patent JP-2017108924-A (JP)
Title: Biological information acquisition device and biological information acquisition method
Inventor: NISHIDA KAZUHIRO
IPC: A61B5/1477
Filed: 2015-12-17
Abstract: PROBLEM TO BE SOLVED: To improve measurement accuracy at the time of measurement of biological information by utilizing an absorbance of light irradiated to a site of a measurement object.SOLUTION: A biological information acquisition device 1 comprises: a light emission section 10 irradiating light of a striped pattern to a living body; a light reception section 10 receiving the light traveling outside the living body irradiated with the light of the striped pattern by the light emission section 10 and outputting a detection signal; and a biological information acquisition section 30 analyzing the detection signal output from the light reception section 10 and acquiring biological information.SELECTED DRAWING: Figure 1
Patent JP-2016103650-A (JP)
Title: Method for manufacturing semiconductor device, substrate processing apparatus, program, and recording medium
Inventor: SHIMAMOTO SATOSHI
IPC: H01L21/768
Filed: 2015-12-24
Abstract: PROBLEM TO BE SOLVED: To form a thin film which has excellent etching resistance and a low dielectric constant.SOLUTION: A method for manufacturing a semiconductor device comprises: a process of forming a thin film on a substrate; a process of performing heat treatment on the thin film at first temperature higher than temperature of the substrate in the process of forming the thin film thereby removing a first impurity containing moisture and chlorine from the thin film; and a process of performing heat treatment on the thin film at second temperature equal to or higher than the first temperature thereby removing a second impurity containing a hydrocarbon compound from the thin film after being subjected to the heat treatment at the first temperature.SELECTED DRAWING: Figure 4
Patent JP-2017118726-A (JP)
Title: Motor control device
Inventor: FUJIMOTO HIROSHI
IPC: H02P21/00
Filed: 2015-12-25
Abstract: PROBLEM TO BE SOLVED: To provide a motor control device and a motor control method, capable of suppressing a radial force of a sixth electric angle.SOLUTION: A motor control device for controlling a current flowing through a coil of a permanent magnet synchronous motor includes: current command value calculation means for calculating a dq axis current command value on the basis of a motor rotational speed and a motor torque command value; and correction means for correcting the dq axis current command value on the basis of a sixth harmonic current having a sixth order component of the dq axis current flowing through the motor.SELECTED DRAWING: Figure 1
Patent JP-2017117730-A (JP)
Title: Acceleration cavity and accelerator
Inventor: YOSHIDA MITSUHIRO
IPC: H05H7/18
Filed: 2015-12-25
Abstract: PROBLEM TO BE SOLVED: To provide an acceleration cavity capable of improving power efficiency by improving a Q factor further than a conventional normally conductive acceleration cavity, and an accelerator.SOLUTION: A high frequency acceleration cavity 1 comprises: a casing 3 of which the inner peripheral face is formed cylindrical and which has conductivity at least on a surface; and multiple acceleration cells 2 provided within the casing 3 and each being a dielectric body with an opening 5a through which a charged particle can pass, formed in a central part. The casing 3 includes: a cylindrical part 6 having a cylindrical shape; and end plates 7 which are installed in both ends of the cylindrical part 6. The multiple acceleration cells 2 are disposed from the end plate 7 at one end side of the casing 3 to the end plate 7 at the other end side. Each of the acceleration cells 2 includes: a cylindrical part 4 having a smaller diameter than an inner diameter of the cylindrical part 6 of the casing 3; and a disc part 5 which is fixed to the cylindrical part 4 inside of the cylindrical part 4 and with which an opening 5a is formed, in such a manner that a plate surface becomes vertical to a passage axis of charged particles.SELECTED DRAWING: Figure 1
Patent JP-2017113729-A (JP)
Title: Membrane cleaning agent, membrane cleaning liquid and cleaning method of membrane
Inventor: KAMEDA HIDEKUNI
IPC: B01D65/02
Filed: 2015-12-25
Abstract: PROBLEM TO BE SOLVED: To provide a membrane cleaning agent, a membrane cleaning liquid and a cleaning method of a membrane where the recoverability of membrane performance is excellent in comparison with a conventional cleaning technique, the cleaning of a pretreatment membrane can be effectively performed in a short time and the problem of membrane deterioration does not occur.SOLUTION: In a membrane cleaning agent, a membrane cleaning liquid and a cleaning method of a membrane: a pretreatment membrane is cleaned by using both hypochlorous acid and/or hypochlorite and a polyphosphoric acid and/or a polyphosphate; hypochlorous acid (salt) is excellent in the decomposition and removal effect of organic matter as an oxidant; meanwhile, a polyphosphoric acid (salt) functions as a dispersant dispersing a scale component such as iron and the like and is excellent in an effect suppressing the generation of humic-iron being an organic-inorganic composite and the like; and then excellent cleaning effect is obtained since the effect acts synergistically by using both hypochlorous acid (salt) and the polyphosphoric acid (salt).SELECTED DRAWING: Figure 1
Patent JP-2017117339-A (JP)
Title: Information processing device, information processing program, and information processing system
Inventor: SAKAI NARUMICHI
IPC: G06T7/00
Filed: 2015-12-25
Abstract: PROBLEM TO BE SOLVED: To allow data synchronization communication between two terminal devices to be optimized.SOLUTION: In an information processing device, a division unit divides first data at a division position based on change information with respect to each subregion. A calculation unit calculates a first feature quantity with respect to each of division regions into which the first data is divided at division positions. In an information processing device of a first embodiment, a change processing unit performs an update process on the basis of a result of comparing the first feature quantity and a second feature quantity calculated from second data with respect to each division region.SELECTED DRAWING: Figure 15
Patent JP-2016124785-A (JP)
Title: Expansive composition
Inventor: KOBAYASHI KUMIKO
IPC: C04B22/06
Filed: 2015-12-25
Abstract: PROBLEM TO BE SOLVED: To provide a caustic lime-based expansive composition capable of adjusting hydration reaction time of caustic lime itself with manufacturing processes as small as possible so that higher expansive amount can be developed than conventional caustic lime-based expansive materials.SOLUTION: There is provided an expansive composition containing caustic lime solid eluting Mg of 0.7 to 2.5 mass% in terms of MgO as an active ingredient. There is provided an expansive composition having caustic lime percentage content of 45 mass% or more (including 100 mass%) and containing caustic lime solid eluting Mg of 0.7 to 2.5 mass% in terms of MgO as an active ingredient.SELECTED DRAWING: None
Patent JP-2017114564-A (JP)
Title: Buffer for transport container and cask
Inventor: ICHIHASHI TAKESHI
IPC: G21F9/36
Filed: 2015-12-25
Abstract: PROBLEM TO BE SOLVED: To provide buffer for a transport container which has high cushioning performance at a low cost, and a cask.SOLUTION: A buffer 10 for a transport container, which is mounted on a transport container 12 which can accommodate an object to be transported, comprises a casing 16 having an internal space, and an impact absorption member 20 which is charged in the internal space. The impact absorption member 20 is formed in such a manner that plural hollow cylindrical bodies 22, which are configured from a wall body in which plural fiber-reinforced plastic sheets are laminated, are arranged in parallel via a flexure allowable space.SELECTED DRAWING: Figure 2
Patent JP-2016127919-A (JP)
Title: Catheter with irrigated tip electrode with porous substrate and high density surface micro-electrodes
Inventor: PAPAIOANNOU ATHANASSIOS
IPC: A61B18/12
Filed: 2015-12-28
Abstract: PROBLEM TO BE SOLVED: To provide a catheter for cardiac tissue ablation and diagnostics.SOLUTION: A catheter 10 has a multifunctional "virtual" tip electrode with a porous substrate and a multitude of surface microelectrodes. The surface microelectrodes are in close proximity to each other so as to sense tissue for localized intracardiac signal detection, and high-density local electrograms and mapping. The porous substrate allows a flow of conductive fluid for ablating tissue. The surface microelectrodes can be formed via a metallization process that allows any shape or size and proximity, and the fluid "weeping" from the porous substrate provides more uniform irrigation in the form of a thin layer of saline. The delivery of RF power to the catheter tip is based on the principle of "virtual electrode", where the conductive saline flowing through the porous tip acts as the electrical connection between the tip electrode and the heart surface. The substrate and the surface electrodes are constructed of MRI compatible materials. The surface electrodes include noble metals, including platinum and gold.SELECTED DRAWING: Figure 1
Patent JP-2017119232-A (JP)
Title: Waterproof ventilation porous film and waterproof ventilation composite material
Inventor: NOSAKA SHIRO
IPC: B01D69/12
Filed: 2015-12-28
Abstract: PROBLEM TO BE SOLVED: To obtain a flexible porous film having high water pressure resistance and permeability.SOLUTION: There is provided a porous film including a first principal surface and a second principal surface on the opposite side to the first principal surface. In the porous film, the rate of hole area of the second principal surface is smaller than the rate of hole area of the first principal surface, the rate of hole area of the second principal surface is 0.5%-30%, a contact angle to water is 70° or more, an average hole area is 0.5 μm-50 μm, and a tensile elastic modulus of a component constituting the porous film is 0.5 MPa-200 MPa.SELECTED DRAWING: Figure 1
Patent JP-2017114105-A (JP)
Title: Artificial wood and its manufacturing method
Inventor: YASUMI YOSUKE
IPC: B29C39/10
Filed: 2015-12-24
Abstract: PROBLEM TO BE SOLVED: To solve problems in a conventional artificial wood in which a lightweight structure can be achieved, however the separation of an adhesive layer occurs due to usage of adhesives such as double-sided tapes to thereby cause corrosion, and therefore there are problems in durability and safety thereof.SOLUTION: An intermediate layer is formed between a cylindrical core material having a predetermined length and diameter and a tubular bark of a seamless structure made of soft polyurethane resin having a diameter larger than the cylindrical core material, and rigid polyurethane resin is injected and molded in the intermediate layer to provide and constitute a jointing material. As a result, the surface-forming bark having elasticity and being safe for a human body is formed in an outer surface, besides, a complete waterproof structure with durability is made possible, and an artificial wood superior in the durability and safety is achieved.SELECTED DRAWING: Figure 1
Patent JP-2015517913-A (JP)
Title: 新規なロウ付けコンセプト
IPC: C22C38/00
Filed: 2013-03-27
Abstract: 本発明は、ロウ付けによる接合及びコーティングのための中間産物に関し、前記中間産物は母材とホウ素及びケイ素の配合物とを含んでおり、前記母材は１０４０℃を超える固相線温度を有しており、前記中間産物は、母材上に前記配合物の表面層を少なくとも部分的に有しており、前記配合物中のホウ素はホウ素源から選択され、前記配合物中のケイ素はケイ素源から選択され、前記配合物はホウ素及びケイ素を含み、ホウ素対ケイ素の割合は約３：１００重量／重量から約１００：３重量／重量の範囲内である。本発明は、積層中間産物、組立中間産物、ロウ付け方法、ロウ付け産物、中間産物の使用、予備ロウ付け産物、配合物及び塗料にも関する。
Patent JP-2015518705-A (JP)
Title: ヒト疾患に関連する生物製剤およびタンパク質の産生のための修飾ポリヌクレオチド
IPC: C12N15/09
Filed: 2013-03-09
Abstract: 本発明は、ポリヌクレオチド、一次転写物、およびｍｍＲＮＡ分子の組成、ならびにこれらの調製、製造、および治療的使用方法に関する。
Patent JP-2015514113-A (JP)
Title: 単一特異性および二重特異性抗ｉｇｆ−１ｒおよび抗ｅｒｂｂ３抗体の用法および用量
IPC: A61K45/08
Filed: 2013-04-02
Abstract: 単独または他の抗癌治療法との併用のどちらかで治療用二重特異性抗ＩＧＦ−１Ｒおよび抗ＥｒｂＢ３抗体を投与する方法を提供する。
Patent JP-2015517277-A (JP)
Title: ストリーム適応およびスプライシングに対するサポートが強化されたビデオコーディング
IPC: H04N19/70
Filed: 2013-04-09
Abstract: クリーンランダムアクセス（ＣＲＡ）ピクチャに基づくストリーム適応およびスプライシングの強化されたサポートのための様々な技法が説明される。ブロークンリンクピクチャが存在することを示すスライスヘッダ内のフラグを使用する代わりに、別個のネットワーク抽象レイヤ（ＮＡＬ）ユニットタイプがブロークンリンクピクチャの存在を示すのに使用され得る。一部の実施態様では、第１の別個のＮＡＬユニットタイプが、先行ピクチャのあるブロークンリンクピクチャの存在を示すのに使用され得、一方で第２の別個のＮＡＬユニットタイプが、先行ピクチャのないブロークンリンクピクチャの存在を示す。一部の実施態様では、第３の別個のＮＡＬユニットタイプが、復号可能な先行ピクチャのあるブロークンリンクピクチャの存在を示すのに使用され得る。
Patent JP-2015520155-A (JP)
Title: Ｓｉｒｓ及び／又は敗血症の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
IPC: A61P3/06
Filed: 2013-05-13
Abstract: 本発明は、有効量の特定DPP-4阻害薬の投与を含んでなるSIRS及び／又は敗血症の治療及び／又は予防方法、並びにSIRS及び／又は敗血症を有するか又はそのリスクがある患者の代謝疾患の治療及び／又は予防のための特定DPP-4阻害薬の使用に関する。【選択図】なし
Patent JP-2015525065-A (JP)
Title: Ｔｃｒアルファ欠損ｔ細胞を増殖させるためのプレｔアルファまたはその機能性変種の使用
IPC: A61P37/04
Filed: 2013-05-13
Abstract: pTアルファまたはその機能性変種をTCRアルファ欠損T細胞で発現させ、それにより機能性CD3複合体を回復させることによって、前記細胞を増殖させる方法。本方法は、ドナー由来の初代T細胞を使用する免疫療法の効率を増強するために特に有用である。本方法は、TCRアルファ欠損T細胞を増殖させるためのpTアルファまたはその機能性変種およびそのようなポリペプチドをコードしているポリヌクレオチドの使用を含む。そのような操作された細胞は、特異的低頻度切断エンドヌクレアーゼ、好ましくはTALE-ヌクレアーゼを使用することによって得ることができる。そのような操作された細胞において悪性または感染細胞を標的化するためのキメラ抗原受容体(Chimeric Antigen Receptor)(CAR)、特に多重鎖CARの使用。本発明は、がんおよびウイルス感染を治療するための標準的および安価な養子免疫療法戦略への道を切り開く。
Patent JP-2015523535-A (JP)
Title: 小型魚雷
IPC: F42B19/46
Filed: 2013-03-07
Abstract: 軽量小型魚雷（１２）は、艦体との接触に応じて魚雷（１２）を艦体に保持するように構成された接触取付アセンブリ（２２）と、複数の可燃性要素（１３２）を収容するチャンバ（２４）と、推進操舵アセンブリ（２６）とを有している。上記可燃性要素は、順次点火されて、艦体の材料の融解温度よりも高い燃焼温度で燃焼し、上記推進操舵アセンブリは、前記魚雷（１２）を水中において、前記艦体へ向かって推進および操舵する。前記魚雷（１２）は、無人航空機による運搬および投下を可能とするサイズおよび重量を有するように構成されている。【選択図】図１
Patent JP-2015525277-A (JP)
Title: スルホン化したポリオキサジアゾールポリマー物品
IPC: D01F6/74
Filed: 2013-06-11
Abstract: 式（Ｉ）、並びに、式（ＩＩ）及び（ＩＩａ）のうちの１つ又は両方の繰り返し単位を有するポリマーを有する形状品。（式中、ＱはＳＯ3Ｍであり、且つ、Ｍは１つ以上のカチオンである）
Patent JP-2015527101-A (JP)
Title: 液体の離散的な噴出を分注するためのバネ駆動ポンプ
IPC: A61C17/028
Filed: 2013-06-11
Abstract: 液体の離散的な噴出又は噴射を送るためのポンプアセンブリ１４を有する口内ケア器具１０に関する。ポンプアセンブリは、ポンプハウジング３６と、入口開口内及び出口開口内の一方向弁８０、８２を含む、ハウジングの前方端にある入口／出口アセンブリ３８とを含む。プランジャスリーブ４４は、ハウジング内に配置され、入口及び出口アセンブリと流体密な関係にある中央開口４８を有する。プランジャ５２は、プランジャスリーブの中央開口に、プランジャスリーブの中央開口と流体密な関係で配置される中央部５６を含む。プランジャスリーブは、プランジャスリーブとハウジングの内側表面との間の外側部材５４を含む。圧縮可能なバネ６４は、プランジャの外側部材の前方端とハウジングの後方端との間に配置される。駆動メカニズム７２は、プランジャを後方へ動かし、これによりプランジャスリーブは、真空作用によって器具内のリザーバ２６からの液体で満たされ、次いでプランジャを解放し、バネがプランジャを急速に前方に動かすことを可能にし、プランジャスリーブ内の液体を流体出口から真っ直ぐな噴出で押し出す。
Patent JP-2015526410-A (JP)
Title: ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はａｈｉ１の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法
IPC: A61K39/395
Filed: 2013-06-24
Abstract: ＡＨＩ１遺伝子の変異又は調節不全を有する腫瘍細胞又は対象におけるアポトーシスの誘発において、チミジンキナーゼインヒビターの活性を遮断する生殖系列欠失多型を有する対象における悪性腫瘍を処置するのに適する方法及び組成物を開示する。これらの方法は、ジアンヒドロガラクチトール、ジアンヒドロガラクチトールの誘導体又は類似体、ジアセチルジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトールの誘導体又は類似体、ジブロモズルシトール、及びジブロモズルシトールの誘導体又は類似体などのアルキル化ヘキシトール誘導体を用いるものである。組成物は、このようなアルキル化ヘキシトール誘導体を含むことができる。方法は、ＢＨ３ミメチックの投与をさらに含むことができ、組成物はＢＨ３ミメチックをさらに含むことができる。ＡＨＩ１遺伝子の調節不全を有する対象において、方法は、ＡＨＩ１遺伝子又はＡＨＩ１タンパク質の発現又は活性を変更する薬剤の投与をさらに含むことができ、組成物はこのような薬剤をさらに含むことができる。