baber/WOPTO huggingface dataset:
Patent IL-92952-A0 (IL)
Title: R-enantiomers of n-propargyl-1-aminoindan compounds,their preparation and pharmaceutical compositions containing them
IPC: A61P25/00
Filed: 1990-01-03
Abstract: R-(+)-N-propargyl-1-aminoindane of formula (I) and its pharmaceutically acceptable acid addn. salts are new. (I) is prepd. by reacting R(-)-1-aminoindane with propargyl bromide or chloride in the presence of base (and opt. of solvent), then (I) is isolated by e.g. chromatography, distn. or selective extraction. The racemic starting material can be used instead and (I) then recovered by fractional crystallisation of salts formed with an optically active acid.
Patent IL-95900-A0 (IL)
Title: Haloperoxidase acid optimum chemiluminescence assay system
IPC: C12Q1/28
Filed: 1990-10-03
Abstract: A highly sensitive chemiluminescent indicator system is disclosed for determining the presence or amount of an analyte in a liquid sample. The new acid optimum chemiluminescent indicator system comprises haloperoxidase (halide:hydrogen peroxide oxidoreductase), halide, oxidant and chemiluminigenic substrate. The indicator system acts as a synthesizer of highly reactive singlet molecular oxygen (<1>O2), which reacts with the chemiluminigenic substrate to yield an excited state, oxidized reaction product. The excited state reaction product then relaxes to a lower energy (e.g., ground) state with the emission of measurable light in an amount related to the amount of each of the reaction participants present in a reaction solution. Known, non-rate limiting amounts of three of the reaction participants are provided in an assay solution to determine the presence or amount of the fourth participant in a test sample. The fourth participant in the test sample may be the analyte of interest, or may be produced or consumed in the test sample through one or more preliminary reactions involving the ultimate analyte of interest, with the amount of the fourth participant being related to the amount of analyte in the test solution. Accordingly, the indicator system of the invention may be employed for the determination of a wide variety of analytes. The indicator system operates most efficiently over the range from acid to slightly basic pH, e.g., at a pH of about 3 to about 8. Also described is a variety of illustrative assay formats in which the indicator reaction of the invention may be employed, as well as kits for use in carrying out assays utilizing the haloperoxidase/halide/oxidant/substrate indicator system.
Patent AU-PN520495-A0 (AU)
Title: Reading aid
IPC: G09G5/38
Filed: 1995-09-04
Abstract: A system (11) for presenting textual and/or graphical information for reading. The system includes a visual display unit (15) for displaying the textual and/or graphical information within a general layout screen, a microcomputer including processing means (13) to receive the textual and/or graphical information in an electronically encoded form and process the same for presentation on the visual display unit (15). A computer program (19) is provided for controlling the presentation of the textual and/or graphical information on the visual display unit (15) in a prescribed manner. A keyboard and mouse input (17) is included for inputting control signals to operate the processing means (13) and the computer program (19) or for altering control parameters of same. The computer program (19) sequentially locates discrete and successive portions of the textual and/or graphical information at the same position on the layout screen at a prescribed blanking time apart, each portion being displayed at this position for a prescribed display time. The general layout screen is divided into a browser pane (37) for displaying a block of textual and/or graphical information to be presented and a flash pane (39), within which the position for sequentially locating the discrete and successive portions of the textual and/or graphical information is centrally situated.
Patent FI-20012175-A0 (FI)
Inventor: MUHONEN JUKKA
IPC: D21F1/08
Filed: 2001-11-09
Abstract: Adjusting the operation of a wire section, in which the development of the consistency of stock on the wire section ( 2 ) is determined and the effect of the consistency determined above on the formation and/or porosity of a paper web ( 3 ) is determined. The consistency developed on the wire section is adjusted based on a quality property of paper and/or by optimising a cost function, the quality property of paper comprising the formation and/or the porosity and/or a combination defined by means of the formation and/or the porosity and the cost function including the effect of at least the formation and/or the porosity.
Patent FI-20060371-A0 (FI)
Inventor: KORKEAKANGAS NIKO
IPC: B66B/
Filed: 2006-04-18
Abstract: A method and an appliance for collecting rope are provided, in which the rope is arranged to be collected in a collection container. The rope to be collected is pushed into the collection container through a tubular guide element in such a way that the collection container is made to rotate around its axis of rotation by means of the pushing force of the rope.
Patent FI-20060639-A0 (FI)
Inventor: LAIVO PASI
IPC: B27L/
Filed: 2006-06-30
Abstract: A chip spiral, the construction of which is such that it can be reliably and efficiently used for chipping all kinds of wood, wood products, semi-finished products, blanks, waste wood and material comparable to wood. The chip spiral comprises helical blades (18) and a frame structure (18). The blades (18) are attached to the frame structure (20) and the structure is formed so that its central part is open, whereby the chips are discharged from the chip spiral via its hub. The power requirement of the construction is smaller than in prior art while the chip production rate per time unit is larger.
Patent IL-102912-A0 (IL)
Title: Multiple fire endoscopic stapling mechanism
IPC: A61B17/04
Filed: 1992-08-23
Abstract: A unique hernia repair stapler (10) is described which allows the forming of staples (20) to attach prosthetics to tissue, or to approximate herniated tissue. The stapler is useful in endoscopic operations and may be rotatable or stationary. The stapler has a unique forming and ejecting mechanism; as well, there is the availability of a loading mechanism useful for both cartridges and magazines of staples. An improved staple shape allows for better staple alignment, especially in a multiple load device.
Patent IL-104460-A0 (IL)
Title: 3'-derivatized oligonucleotide analogs with nonnucleotidic groupings,their preparation and use
IPC: A61K48/00
Filed: 1993-01-20
Abstract: Oligonucleotide analogs (I) and their physiologically tolerable salts. Oligonucleotide analogs and their physiologically tolerable salts of formula (I) are new. R<1> = H, a substituent or -P(=W)ZZ'; R<2> = H, OH, 1-18C alkoxy, halo, azido or amino; B = nucleotide base residue; A = oxy or methylene; d, e, f = 0-50; i = 1-10; r = 0 or 1; W = oxo, selenoxo or thioxo; V = oxy, sulfandiyl or imino; Y = oxy, sulfandiyl, imino or methylene; Y' = oxy, sulfandiyl, imino, (CH2)m or V(CH2)m; m = 1-18; X = OH or SH; U, R<3>, R<4> = substituents; p = 1-100; q = 0-18; R<11> = H or functional group; Sp = a (3',5'-) spacer group of formula (i); g, g' = 0 or 1; h = 0-10; G = 1-12C alkylene (optionally substituted), (6-14C)aryldi-(1-8C)alkylene, 6-18C arylene, (CH2CH2V) alpha CH2CH2, (CH2V) alpha CH2, -(G-Y-P(=W)(U)-Y'-) beta  or a group of formula (ii);  alpha  = 1-11;  beta  = 1-6; Z, Z' = OH, (seleno)thio or a substituent; provided that r is 0 when V is Y' and is 1 if i is greater than 1. Positions of R<2> and the adjacent phosphoryl residue can be reversed; each nucleoside had D- or L-configuration and each B has alpha  or  beta  configuration. Independent claims are also included for: (1) a method for producing (I); (2) the phosphitylation reagent of formula DMTr-X'-G'-Y''-P(U')(NR<5>R<6>); and (3) a pharmaceutical composition containing at least one compound (I) and optionally auxiliary, carrier and/or other active agents. R<5>, R<6> = 1-12C alkyl or together form a 5-6 membered ring; DMTr = dimethoxytrityl; X', Y'' = oxy or sulfandiyl; U' = 1-4C alkyl or protected OH; G' = (CH2CH2O) alpha CH2CH2 or CH2CH(OR')CH2; and R' = 1-18C alkyl, 6-14C aryl or 6-14C aryl(1-8C) alkyl.
Patent IL-107384-A0 (IL)
Title: Aqueous release coating composition
IPC: C09D133/08
Filed: 1993-10-25
Abstract: The invention is directed to an aqueous release coating comprising a polymer and an aqueous solution or dispersion of an alkylester trimethyl quaternary ammonium salt or tallow trimethyl quaternary ammonium salt. The invention is also directed to use of a layer of the aqueous release coating composition on a layer of pressure sensitive adhesive on a backing layer. The aqueous release coating layer permits the pressure sensitive adhesive layer to be easily separated from the backing layer, even after storage for long durations and under extreme temperature and humidity conditions. The aqueous release coating does not migrate into the pressure sensitive adhesive layer and interfere with the adhesive properties of the pressure sensitive adhesive.
Patent IL-115903-A0 (IL)
Title: Use of dioxomorpholines for combating endoparasites new dioxomorpholines and processes for their preparation
IPC: C07C229/50
Filed: 1995-11-07
Abstract: PCT No. PCT/EP95/04255 Sec. 371 Date May 2, 1997 Sec. 102(e) Date May 2, 1997 PCT Filed Oct. 30, 1995 PCT Pub. No. WO96/15121 PCT Pub. Date May 23, 1996The present invention relates to the use of dioxomorpholines of the formula (I)    <IMAGE>  (I)  in which the radicals R1 to R5 have the meanings given in the description, their use for combating endoparasites and new dioxomorpholines and processes for their preparation.
Patent IL-122432-A0 (IL)
Title: Transdermal patch for preventing ovulation
IPC: A61K47/32
Filed: 1996-06-06
Abstract: Compositions and methods for preventing ovulation in a woman are provided, as well as compositions and methods for female hormone replacement therapy. The compositions can be administered by the use of a transdermal patch. The patch will administer 17-deacetyl norgestimate alone or in combination with an estrogen such as ethinyl estradiol to women.
Patent IL-123571-A0 (IL)
Title: Process for aqueous granulation of clarithromycin
IPC: A61K31/7042
Filed: 1996-10-18
Abstract: The present invention provides a process for the aqueous granulation of a macrolide antibiotic which comprises mixing a macrolide antibiotic and a carbomer; wetting the mixture with water; and blending the mixture to allow formation of a macrolide antibiotic-carbomer granule.
Patent IL-126502-A0 (IL)
Title: Active detection system
IPC: G08B13/12
Filed: 1998-10-08
Abstract: An intrusion detection fence and system is provided. In one embodiment, the fence includes a plurality of trip wires secured between a pair of anchor posts, a plurality of detector posts anchored in the ground, located between the anchor posts, at least one actuator attached to each of the detector posts, the actuator also being coupled to each of the plurality of trip wires; and a detecting device attached to the actuator and secured to each of the detector posts. The deflection or cutting of any of the plurality of trip wires activates at least one of the detecting devices adjacent to the activated trip wires.
Patent IL-127178-A0 (IL)
Title: Process for preparing 2-fluoro-1- cyclopropanecarboxylic acid derivatives by reductive dehalogenation
IPC: C07C69/74
Filed: 1997-04-30
Abstract: PCT No. PCT/EP97/02210 Sec. 371 Date Nov. 16, 1998 Sec. 102(e) Date Nov. 16, 1998 PCT Filed Apr. 30, 1997 PCT Pub. No. WO97/44309 PCT Pub. Date Nov. 27, 1997Cyclopropanecarboxylic acid derivatives are prepared by reacting halogenocyclopropanecarboxylic acid derivatives with metals in the presence of bases and with or without addition of hydrogen in an advantageous manner if the base is added during the reaction. By means of the process according to the invention, good yields and selectivities and a high proportion of cis isomers in the reaction product may be achieved.
Patent IL-149063-A0 (IL)
Title: Process to prepare aryltriazolinones and novel intermediates thereto
IPC: C07C257/22
Filed: 2000-10-12
Abstract: A process is described for preparing 1-aryltriazolinones of formula I useful in the production of commercial herbicides: by (i) carbonylating an amidrazone of formula (A) with one or more carbonylating agent, or by (ii) condensing a hydrazonoyl derivative of formula (A) with one or more ring-forming agent, wherein formula (A) is where W, X, Y, Z, and R<SUP>1 </SUP>are fully described herein. Preferred are those where W is halogen or -NHR where R is hydrogen or haloalkyl; X and Y are independently selected from hydrogen, chloro, or fluoro; Z is hydrogen, bromo, iodo, nitro, amino, or methylsulfonylamino; and R<SUP>1 </SUP>is methyl. Certain compounds of formula (A) are novel compositions of matter. The process as described herein has utility in providing compounds of formula I in unexpectedly high yield and purity.
Patent IL-151816-A0 (IL)
Title: Synergistic herbicidal mixtures
IPC: A01N43/824
Filed: 2001-04-04
Abstract: The present invention provides cereal selective herbicidal compositions comprising a herbicidally acceptable carrier and/or surfactant and, as active ingredient, herbicidally effective amount of at least one 6-phenoxypyrid-2-ylcarboxamide of formula I <CHEM> and at least one additional herbicidal compound selected from the group consisting of flufenacet, cinidon-ethyl and carfentrazone-ethyl. <??>Also provided is a method for the control of undesirable plants such as Setaria viridis, Alopecurus myosuroides, Poa annua, Stellaria media, Lamium purpureum, Galium aparine, Veronica hedera efolia, Papaver rhoeas and Matricaria inodora which comprises applying to the plants or their locus a herbicidally effective amount of said compositions. The compositions have been found to possess synergistic properties.
Patent IL-153547-A0 (IL)
Title: Process for preparing phenyl substituted azole derivatives
IPC: C07D233/64
Filed: 2001-07-26
Abstract: The present invention provides of method of preparing phenyl-substituted azoles. This method uses an efficient ligand-accelerated Ullmann coupling reaction of anilines with azoles. The coupling products are useful for preparing factor Xa inhibitors.
Patent IL-154949-A0 (IL)
Title: Imidazole derivatives as raf kinase inhibitors
IPC: A61K49/00
Filed: 2001-09-19
Abstract: Novel compounds and their use as pharmaceuticals particularly as Raf kinase inhibitors for the treatment of neurotraumatic diseases, cancer, chronic neurodegeneration, pain, migraine and cardiac hypertrophy.
Patent IL-156042-A0 (IL)
Title: Method for producing a phenylene-bis-benzimidazole-tetrasulfonic acid disodium salt
IPC: C07B61/00
Filed: 2001-11-21
Abstract: A reaction time of 10-15 hours is used in a method for the production of phenylene-bis-benzimidazole-tetrasulfonic acid di-sodium salt (I) by reacting o-phenylenediamine with terephthalic acid and chlorosulfonic acid in the presence of a strong acid.
Patent IL-157841-A0 (IL)
Title: Activation of natural killer cells by adenosine a3 receptor agonists
IPC: A61P7/06
Filed: 2002-04-11
Abstract: The present invention is based on the surprising finding that adenosine A3 receptor agonists (A3RAg) are capable of activating natural killer (NK) cells. In particular, methods and pharmaceutical compositions for activating NK cells in an individual comprising administering said individual with an effective amount of one or more A3RAg are provided herein. A further method includes treatment of a disease comprising administering to an individual in need of such treatment NK cells a priori activated with an effective amount of at least one A3RAg. The NK cells may be either autologous cells or cells withdrawn from a donor individual. Further provided are pharmaceutical compositions comprising one or more A3RAg in an amount effective to achieve a therapeutic effect, the therapeutic effect comprising activation of NK cells, the pharmaceutical composition optionally comprising physiologically acceptable additives.
Patent IL-159446-A0 (IL)
Title: Needle electrode
IPC: A61N1/05
Filed: 2002-06-10
Abstract: Needle electrode for therapy, especially percutaneous galvanotherapy of tumors, which can be visualized by image-generating procedures, which is provided with a coating of platinum and/or an insulating material, as well as a process for the manufacture of the needle electrode according to the invention.
Patent IL-162048-A0 (IL)
Title: Method for manufacturing an orifice mechanism capable of low fluid flow rates
IPC: A61M5/168
Filed: 2004-05-19
Abstract: A method for manufacturing an orifice mechanism includes the steps of providing a mandrel having a length and helically wrapping a winding around at least a portion of the length of the mandrel. The mandrel and the winding define a first channel for carrying a drug therethrough. An inlet is at one end of the winding and an outlet is at the other end of the winding. <IMAGE>
Patent IL-181763-A0 (IL)
Title: Edible food container and method of making same
Filed: 2007-03-07
Abstract: An edible food container comprises a main body ( 2 ) having a central portion for supporting food ( 3 ), at least one peripheral portion ( 4 ) extending therefrom for laterally containing food. The central portion ( 3 ) and the peripheral portion ( 4 ) are both made of the same edible material. Furthermore, the peripheral portion ( 4 ) has one or more removable areas ( 5 ) having differential mechanical strength from the central portion ( 3 ) to facilitate separation and removal of such one or more removable areas ( 5 ) by a user.
Patent IL-191754-A0 (IL)
Title: Formulation
Filed: 2008-05-27
Abstract: A product comprising microcapsules which themselves comprise (a) a polymeric shell; and (b) a core which comprises (i) a solid agrochemical dispersed in a matrix and (ii) a water-immiscible liquid characterized in that the matrix is distributed non-continuously throughout the water-immiscible liquid.
Patent RO-133567-A0 (RO)
Title: Guiding device with rotary bush for piston rod guiding
Inventor: CIURLEA CRISTIAN
IPC: E21B17/10
Filed: 2019-04-24
Abstract: The invention relates to a guiding device with rotary bush for guiding the piston rod intended to be mounted at the top of the cylinder assembly of the bore-hole pump and to guide the pump piston rod. According to the invention, the guiding device comprises a device body (1), a rotary bush (2) with some helical entraining elements (21), a seat (3), at each upwards stroke of the bore-hole pump piston, the pumped fluid entering the helical grooves (21) provided at the bottom of the rotary bush (2), imparting the bush (2) a rotary motion and an axial upward motion, while, at the downwards stroke, the rotary bush (2) rests on the seat (3) and guides a piston rod (4), thereby ensuring, at each stroke, another contact line with the piston rod (4).
Patent AP-2000001844-A0 (AP)
Title: Container.
Inventor: WHEELER ARTHUR
IPC: A01N1/02
Filed: 1998-11-24
Abstract: A portable container (10)for receiving contents for transport whilst regulating the temperature of the contents comprises combined heating and/or cooling means in the form of a peltier effect device (50), a removable inner receptacle (70)for receiving the contents, an air gap around the outside of the inner receptacle, and a control unit (62)for controlling the peltier effect device so as to regulate the temperature of the air around the outside of the inner receptacle and thereby regulate the temperature of the contents of the inner receptacle. The control unit can have a temperature logging system for recording the temperature history of the contents of the container.
Patent IE-910410-A1 (IE)
Title: A process for purifying lipocortins
IPC: C12P21/00
Filed: 1991-02-07
Abstract: A process for the purification of lipocortins, especially of the proteins, prepared by genetic manipulation, rPP4, rPP4-X and rPP4-delta, by treatment of a solution of a lipocortin with an anion exchanger in the presence of a chelating agent and of a detergent is described.
Patent MA-26474-A1 (MA)
Inventor: ELISABETH COLETTE LOUISE GAUTI
IPC: A61P25/16
Filed: 1998-02-25
Abstract: This invention relates to 2,3(1H,4H)-quinoxalinedione derivatives which are selective antagonists of N-methyl-D-aspartate receptors. More particularly, this invention relates to 5-triazolyl-2,3(1H,4H)-quinoxalinedione derivatives and to the preparation of, compositions containing, and the uses of, such derivatives. It also relates to a method for treating acute neurodegeneration disorders and chronic neurological disorders.
Patent MA-37981-A1 (MA)
Title: Protéines à domaine d'échafaudage à base de fibronectine qui se lient à la myostatine
Inventor: CLOAD SHARON
IPC: C07K14/435
Filed: 2013-09-12
Abstract: La présente invention concerne des protéines à domaine d'échafaudage à base de fibronectine qui se lient à la myostatine. L'invention concerne également l'utilisation de ces protéines dans des applications thérapeutiques pour traiter la dystrophie musculaire, la cachexie, la sarcopénie, l'arthrose, l'ostéoporose, le diabète, l'obésité, copd, une néphropathie chronique, l'insuffisance cardiaque, un infarctus du myocarde et une fibrose. L'invention concerne en outre des cellules comportant de telles protéines, des polynucléotides codant pour de telles protéines ou leurs fragments, et des vecteurs comportant les polynucléotides codant pour les protéines.
Patent MA-45632-A1 (MA)
Title: Boite d'encastrement ronde avec de scellage renforce dans le mur
Inventor: OTHMANE SEKKAT
IPC: H02G3/08
Filed: 2019-04-19
Abstract: La boîte ronde d'encastrement objet de la demande de brevet et munie d'une couronne remplaçant la collerette de renfort comportant des ouvertures de dimensions identiques et séparations identiques pour permettre le glissement du ciment des deux cotés de la couronne et ainsi le renforcement du scellage dans le mur, sans risque de détachement, afin d'assurer une meilleure fixation de l'appareillage électrique.
Patent UY-23752-A1 (UY)
Title: Gel adhesivo trixotropico para madera
Inventor: COLUMBUS PETER SPIROS
IPC: C08L31/04
Filed: 1994-03-30
Abstract: Esta invención se refiere a una emulsión de gel adhesivo de polivinilacetato, tixotropico, de base acuosa, de uso general para maderas; donde dicha emulsión comprende: agua, acetato de polivinilo, alcohol de polivinilo, goma cantan, glioxal y harina de madera. En una realización particular se incluye un gel conforme a lo descrito donde la cantidad de harina de madera es suficiente como para proveer propiedades de manchado o teñido y ligado al adhesivo seco.
Patent UY-26297-A1 (UY)
Title: Vacuna
Inventor: COLAU BRIGITTE DESIREE ALBERTE
IPC: C12N/
Filed: 2000-08-16
Abstract: Esta invención se refiere a nuevas formulaciones de vacuna, a procedimientos para prepararlas y a su uso en terapia. En particular, la presente invención se refiere a nuevas formulaciones de vacuna de rotavirus.
Patent UY-27451-A1 (UY)
Title: 2,5-diamidoindoles sustituidos y su utilización
Inventor: KELDENICH DR
IPC: C07D405/12
Filed: 2002-09-24
Abstract: Se describen compuestos de fórmula (I) un procedimiento para su preparación así como su empleo medicamentos para el tratamiento de enfermedades de hombres y/o animales.
Patent UY-27465-A1 (UY)
Title: Métodos y composiciones para tratar flavivirus y pestivirus con 4' modificaciones nucleosides
Inventor: JEAN-LOUIS IMBACH
IPC: A61K38/14
Filed: 2002-10-01
Abstract: Se proporciona un método y una formulación para tratar un receptor infectado con flavivirus o pestivirus el cual comprende administrar una cantidad efectiva