baber/WOPTO huggingface dataset:
Patent WO-2020257677-A1 (WO)
Inventor: AUSTRING RONALD
IPC: G16H10/00
Filed: 2020-06-19
Abstract: An Electronic Health Record (EHR) data blockchain system configured to allow multiple entities (e.g., pharmacy industry entities that can act as data, service, product providers, and consumers) to conned to an EHR patient transaction blockchain (e.g., EHR-DATA-BC) and an EHR Data Patient Portal (e.g., EHR-Data-PP) to provide a centralized location for messages and subsequent edits to ensure uniform message data is presented. The EHR data blockchain system can include an EHR Data API, an EHR patient transaction blockchain API, and an EHR patient transaction blockchain. The EHR Data API can access and retrieve patient identifiable information (PII) and generate a non-patient-identifiable Single Purpose Patient ID (SPPID) for a particular patient The EHR patient transaction blockchain API (e.g., EHR-DATA-BC-API) can store the SPPID, store particular, discrete data retrieved from the EHR for a patient, execute smart contracts, and control the execution of digital currency transfers, among other functions.
Patent WO-2021003254-A1 (WO)
Title: Milieu de cryoconservation comprenant un extrait de tissu
Inventor: TAGHIZADEH ROUZBEH
IPC: A61K35/407
Filed: 2020-07-01
Abstract: La présente invention concerne un milieu de cryoconservation qui comprend un extrait de tissu, et un procédé de cryoconservation de cellules et/ou de tissus à l'aide du milieu de cryoconservation.
Patent WO-2021021439-A1 (WO)
Inventor: CHEN WANSHI
IPC: H04L1/18
Filed: 2020-07-15
Abstract: Methods, systems, and devices for wireless communications are described. According to one or more aspects, a device, such as a user equipment (UE), may receive downlink control information, and may determine assignment information for processing batch-based feedback based on the downlink control information. The UE may determine the batch-based feedback for a batch of downlink transmissions (for example, transmissions associated with packets of information) that are configured to be processed together by the UE. The UE may receive a downlink transmission from the base station, and may construct a codebook based on assignment information and the downlink transmission. In some examples, the UE may determine acknowledgment feedback for the downlink transmission based on the codebook. The UE may transmit the acknowledgment feedback to the base station.
Patent WO-2021016208-A1 (WO)
Inventor: GHOSH SANGITA
IPC: A61K38/22
Filed: 2020-07-20
Abstract: Les patients atteints d'hyperplasie surrénale congénitale (CAH) ont besoin de soins et de traitements adéquats pour mener des vies normales. Il existe donc un besoin pour de nouvelles méthodes de traitement de la CAH. La présente invention concerne de nouveaux composés, des sels, des compositions et des utilisations de ceux-ci dans le traitement de la CAH.
Patent WO-2021016361-A1 (WO)
Title: Methods and compositions for treating cancer using peptide nucleic acid-based agents
Inventor: ROTHMAN JEFFREY HAROLD
IPC: A61K47/42
Filed: 2020-07-22
Abstract: The present disclosure provides,  inter alia , improved PNA agents, compositions comprising the same, and methods for treating diseases such as cancers by using such agents and / or compositions. Methods for reducing expression of a gene in a cell are also provided.
Patent WO-2021022131-A1 (WO)
Inventor: LI JUNYI
IPC: H04W84/04
Filed: 2020-07-31
Abstract: Methods, systems, and devices for wireless communications are described. For example, the described techniques provide for wireless device (e.g., wireless repeater, wireless relay device, smart repeater, etc.) operation in a low power state, and base station signaling for triggering of wireless repeater control interface configuration. For example, a wireless repeater may operate in a power saving mode and monitor for control information from a base station according to a low power state or a slow state (e.g., according to a long monitoring periodicity relative to a monitoring periodicity associated with a full power state or fast state). Upon detection of triggering signal from a base station, the wireless repeater may transition to monitoring for control information from the base station according to a fast state (e.g., according to a short, or more frequent, monitoring periodicity relative to a monitoring periodicity associated with a low power state).
Patent WO-2021071578-A1 (WO)
Title: Method and apparatus for forming holes
Inventor: LUCCIA PAUL
IPC: G01C17/38
Filed: 2020-08-11
Abstract: An apparatus, system, or method for forming holes and shapes in surfaces may be disclosed. The apparatus may be a drain or drain- shaped tool which may be affixed to a drilling device. The apparatus may be fitted with an abrasive material, sharp edges, or a serrated edge to increase the performance and efficiency of the apparatus. The system and method may incorporate the use of a drilling device, such as a handheld drill or a drill press. A first step may involve affixing a drain to a drilling device. In a next step, the user may contact the drain drilling device with a work surface and may power on the drilling device. The hole created may be recessed such that the surrounding area is incrementally deeper closer to the hole in the center.
Patent WO-2021030373-A1 (WO)
Inventor: MAYHEW CHRISTOPHER NORMAN
IPC: C12N5/00
Filed: 2020-08-11
Abstract: Disclosed herein are organoids, or compositions thereof, produced through a process of aggregating gut endoderm monolayer and culturing the resultant gut endoderm aggregate. Examples of these aggregated organoids include but are not limited to aggregated liver organoids, aggregated gastric organoids, aggregated intestinal organoids, and aggregated colonic organoids.
Patent WO-2021045947-A1 (WO)
Title: Methods and systems for diagnosing from whole genome sequencing data
Inventor: EBERLE MICHAEL
IPC: G16B20/20
Filed: 2020-08-26
Abstract: Disclosed herein include systems, devices, computer readable media, and methods for paralog geno typing, such as determining a copy number of survival of motor neuron 1 gene and genotyping cytochrome P450 family 2 subfamily D member 6 gene using a Gaussian mixture model comprising a plurality of Gaussians each representing a different integer copy number.
Patent WO-2021055228-A1 (WO)
Inventor: GNANASAMBANDAM NATHAN
IPC: G06Q10/00
Filed: 2020-09-10
Abstract: L'invention concerne un procédé et un système d'application polyvalente autonome de planification, d'inscription et d'éducation. L'application polyvalente autonome peut fournir une expérience améliorée à des utilisateurs qui planifient des rendez-vous avec des personnes ayant des spécialités, et qui s'inscrivent aux rendez-vous planifiés. Une plateforme d'intelligence cognitive peut faire appel à des techniques d'intelligence artificielle pour permettre des opérations de l'application polyvalente autonome. En outre, des ressources informatiques peuvent être réduites à l'aide des techniques décrites.
Patent WO-2021055865-A1 (WO)
Title: Selective drug release from internalized conjugates of biologically active compounds
Inventor: BINDMAN NOAH
IPC: A61K47/64
Filed: 2020-09-18
Abstract: The invention relates to conjugates of biologically active compounds, wherein such a conjugate is comprised of a sequence of amino acids containing a tripeptide that confers selective cleavage by tumor tissue homogenate for release of free drug and/or improves biodistribution into the tumor tissue in comparison to normal tissue homogenate from the same species, wherein the normal tissue is the site of an adverse event associated with administration to a human subject in need thereof of a therapeutically effective amount of a comparator conjugate whose amino acid sequence is a dipeptide known to be selectively cleavable by Cathepsin B.
Patent WO-2021076884-A1 (WO)
Inventor: AKL NAEEM
IPC: H04L1/18
Filed: 2020-10-16
Abstract: In some aspects, a network node may determine a connection identifier associated with transmitting data to a decoder node via multiple paths, wherein the connection identifier is associated with a single radio bearer of a user equipment (UE); encode a first portion of data into first packets and second packets; transmit the first packets and the connection identifier to the decoder node via a first path; transmit the second packets and the connection identifier to the decoder node via a second path; receive a response from the decoder node, wherein the response includes the connection identifier; and transmit, to the decoder node and based at least in part on the response, one of: third packets, encoded from the first portion of data, and the connection identifier, or one or more sets of packets, encoded from a second portion of data, and the connection identifier.
Patent WO-2021091928-A1 (WO)
Inventor: ZHANG XUSHENG
IPC: A61N1/39
Filed: 2020-11-04
Abstract: A medical device is configured to determine time intervals between consecutive cardiac events sensed from a cardiac electrical signal, increase a value of a tachyarrhythmia interval count in response to each of the determine time intervals detected as a tachyarrhythmia interval. The device is further configured to detect normal sinus rhythm events and the decrease the value of the tachyarrhythmia interval count in response to a threshold number of detected normal sinus rhythm events.
Patent WO-2021188170-A1 (WO)
Title: Colorimetric detection of shale inhibitors and/or salts
Inventor: JAMISON DALE E
IPC: E21B49/00
Filed: 2020-12-09
Abstract: A method of detecting a shale inhibitor and/or a salt content in a wellbore servicing fluid (WSF), the method comprising determining a water salinity of a wellbore servicing fluid; dosing a known volume of the wellbore servicing fluid into a container; optionally adding a known volume of diluent (e.g., water) and mixing to provide a test sample; combining the test sample with a chromophore specific to the shale inhibitor and/or the salt, respectively, and optionally mixing; measuring the shale inhibitor content and/or the salt content, respectively, of the test sample using colorimetry; reporting the data from the measuring to a computer control system; determining a wellbore servicing fluid treatment based on the measured shale inhibitor content and/or salt content; subjecting the wellbore servicing fluid system to the treatment; and optionally waiting for a waiting time to retest the wellbore servicing fluid system and repeating.
Patent WO-2021206762-A1 (WO)
Title: Zone-append command scheduling based on zone state
Inventor: BENISTY SHAY
IPC: G06F3/06
Filed: 2020-12-11
Abstract: The present disclosure generally relates to scheduling zone-append commands for a zoned namespace (ZNS). Rather than taking zone-append commands in order or randomly, the zone-append commands can be scheduled in the most efficient manner consistent with the open zones of the ZNS. A zone priority is determined based upon the length of time that a zone has been open together with the zone status. Generally, the older the zone and/or the more full that a zone is increases the priority. Once the zone priority is established, the zone-append commands are scheduled to ensure the zone- append commands for the high priority zones are processed first so that the open zone can be filled prior to closing.
Patent WO-2021146626-A1 (WO)
Title: Activity-specific cell enrichment
Inventor: LIU JIA
IPC: C12P21/00
Filed: 2021-01-15
Abstract: An activity-specific cell-enrichment method, capable of selection of high-performing host cells and/or expression vectors from a genetically diverse pool of host cells that can comprise expression vectors is provided.
Patent WO-2021167824-A1 (WO)
Title: Techniques for sharing sidelink resource
Inventor: CHOI CHANG-SIK
IPC: H04W72/02
Filed: 2021-02-10
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a recipient user equipment (UE) of a sidelink resource sharing system may receive, from a plurality of provider UEs, resource information associated with the plurality of provider UEs; select, based at least in part on a ranked order and the resource information, one or more resources associated with one or more selected UEs, of the plurality of provider UEs, wherein the ranked order is based at least in part on measurement information, determined by the recipient UE, associated with the plurality of provider UEs; and perform a sidelink communication using the one or more resources. Numerous other aspects are provided.
Patent WO-2021163421-A1 (WO)
Title: Recombinant bacteria engineered to treat diseases associated with methionine metabolism and methods of use thereof
Inventor: ISABELLA VINCENT
IPC: C12N15/00
Filed: 2021-02-12
Abstract: The present disclosure provides recombinant bacterial cells that have been engineered with genetic circuitry which allow the recombinant bacterial cells to sense a patient's internal environment and respond by turning an engineered metabolic pathway on or off. When turned on, the recombinant bacterial cells complete all of the steps in a metabolic pathway to achieve a therapeutic effect in a host subject. These recombinant bacterial cells are designed to drive therapeutic effects throughout the body of a host from a point of origin of the microbiome. Specifically, the present disclosure provides recombinant bacterial cells that comprise an amino acid catabolism enzyme, e.g., a methionine catabolism enzyme for the treatment of diseases and disorders associated with amino acid metabolism, including homocystinuria, in a subject. The disclosure further provides pharmaceutical compositions and methods of treating disorders associated with amino acid metabolism, such as homocystinuria.
Patent WO-2021174199-A1 (WO)
Title: Procédés et compositions pour identifier des caractères à l'aide d'un système acellulaire
Inventor: SUN ZACHARY Z
IPC: C12Q1/6865
Filed: 2021-03-01
Abstract: La présente invention concerne des procédés et des compositions pour le criblage à l'aide d'un système de transcription/traduction (TXTL) in vitro. Dans certains modes de réalisation, un procédé de criblage peut comprendre : fournir une banque de candidats génétiques à cribler, chaque candidat génétique codant pour une ou plusieurs protéines d'intérêt ; exprimer chaque candidat génétique dans un système de transcription/traduction (TXTL) in vitro, ce qui permet de produire une pluralité de compositions comprenant chacune la ou les protéines d'intérêt ; et soumettre la pluralité de compositions à un dosage pour évaluer un phénotype souhaité, ce qui permet de déterminer si la ou les protéines d'intérêt présentent le phénotype souhaité.
Patent WO-2021183634-A1 (WO)
Title: Resistance to cucumber green mottle mosaic virus in cucumis sativus
Inventor: CANTET MELISSA
IPC: A01H1/04
Filed: 2021-03-10
Abstract: Cucumber plants ( Cucumis sativus ) exhibiting increased resistance to Cumber Green Mottle Mosaic Virus (CGMMV) are provided, together with methods of producing, identifying, or selecting plants or germplasm with a CGMMV resistance phenotype. Such plants include cucumber plants comprising recombinant chromosomal segments conferring CGMMV resistance. Compositions, including novel polymorphic markers for detecting plants comprising introgressed virus resistance alleles, are further provided.
Patent WO-2021202834-A1 (WO)
Title: Spintronic nanodevice for low-power, cellular-level, magnetic neurostimulation
Inventor: WANG JIAN-PING
IPC: A61N1/00
Filed: 2021-04-01
Abstract: A neuro-stimulation system includes a stimulator controller (102/1608), a support surface (106/1605), and a magneto-ionic stimulator (108/1606) positioned on the support surface (106/1605) and electrically connected to the stimulator controller (102/1608). The stimulator controller (102/1608) can apply a voltage to the magneto-ionic stimulator (108/1606), wherein a change in the voltage causes a change in a magnetic field produced by the magneto-ionic stimulator(108/1606).
Patent WO-2021216388-A1 (WO)
Inventor: MANOLAKOS ALEXANDROS
IPC: H04W64/00
Filed: 2021-04-18
Abstract: A positioning method includes: measuring, at a UE, an IB PRS resource on a first frequency band; transmitting, from the UE to a recipient device, an OB PRS resource on a second frequency band; and at least one of: transmitting, from the UE based on the second frequency band being different than the first frequency band, a receive-transmit time difference indication and a band indication indicative of the second frequency band, the receive-transmit time difference indication being indicative of a difference between a time of arrival of the IB PRS resource and a time of departure of the OB PRS resource; or transmitting, from the UE based on the second frequency band being implicit, the receive-transmit time difference indication without transmitting the band indication.
Patent WO-2021225967-A1 (WO)
Title: Systems and methods for positioning a shifting profile geometry
Inventor: LAPLANE CLEMENT
IPC: E21B23/00
Filed: 2021-05-03
Abstract: A method includes disposing an intervention service tool within a tubular. The intervention service tool includes an anchoring system, a shifting system, and a linear actuator system. The tubular includes a shifting profile geometry disposed within the tubular at a first location. The anchoring system, the shifting system, and/or the linear actuator system is actuated. Shifter system pressure, linear actuator system force/pressure, and displacement of the shifting system is measured. A known graph of the shifting profile geometry is compared to one or more of a measured pressure, a measured force, or a measured displacement. A position of a key disposed on the shifting system is determined relative to the shifting profile. The shifting profile geometry is engaged with the key based on the position of the key. The shifting profile geometry is positioned at a second location that is different from the first location.
Patent WO-2021231284-A1 (WO)
Title: Enclosures for running performance anlaysis
Inventor: REYNOLDS JR HARRY
IPC: A61B5/024
Filed: 2021-05-10
Abstract: The present disclosure provides a system for determining running performances using an enclosure. The system includes a running surface within an enclosure. The system can also include sensors, audio devices, display devices, and lighting devices along the length of the running surface. The system can further include user-wearable devices having mobile sensors. Additionally, the system can include a processor and a storage device storing program instructions that control the system to trigger a running performance and log data of the running performance received from the sensors and the mobile sensors. Additionally, the system can generate audiovisual cues using the audio, display, and lighting devices.
Patent WO-2021236619-A1 (WO)
Title: Method for processing advanced high strength steel
Inventor: SKSZEK TIMOTHY W
IPC: C22C38/06
Filed: 2021-05-18
Abstract: A method of manufacturing an energy absorbing component for a vehicle is provided. The method includes heating a bainitic GENS steel material which has a microstructure including ferrite and bainite to a temperature above the Ac3 temperature to convert a portion of the ferrite and bainite to austenite. The method further includes forming while cooling the heated steel blank into a component in a temperature controlled steel die. During the cooling step, the steel material is cooled to a temperature below the Ms temperature to form retained austenite. A portion of the austenite transforms to martensite and bainite during the forming and cooling step. The method can further include heating the component to a temperature above the Ms temperature after the forming and cooling step to increase energy absorption characteristics. During a crash event, the strain imposed on the component converts retained austenite present in the component to martensite.
Patent WO-2021262549-A1 (WO)
Inventor: IRELAND BRETT
IPC: G06F9/38
Filed: 2021-06-18
Abstract: A unified queue configured to perform decoupled prediction and fetch operations, and related apparatuses, systems, methods, and computer-readable media, is disclosed. The unified queue has a plurality of entries, where each entry is configured to store information associated with at least one instruction, and where the information comprises an identifier portion, a prediction information portion, and a tag information portion. The unified queue is configured to update the prediction information portion of each entry responsive to a prediction block, and to update the tag information portion of each entry responsive to a tag and TLB block. The prediction information may be updated more than once, and the unified queue is configured to take corrective action where a later prediction conflicts with an earlier prediction.
Patent WO-2022051015-A1 (WO)
Inventor: TICE JESSE
IPC: H01L21/48
Filed: 2021-06-21
Abstract: L'invention concerne un ensemble circuit intégré comprenant un circuit intégré formé sur un côté d'un substrat et une couche d'étalement thermique composée d'une encre d'argent imprimée directement sur un côté opposé du substrat à partir du circuit intégré, la couche d'étalement thermique éliminant la chaleur générée par le circuit intégré. L'ensemble comprend également un dissipateur thermique fixé thermiquement à la couche d'étalement thermique à l'opposé du substrat, le dissipateur thermique étant fixé à la couche d'étalement thermique par impression du même matériau sur le dissipateur thermique en tant que couche d'étalement thermique et par pression de la couche d'étalement sur le dissipateur thermique.
Patent WO-2021262709-A1 (WO)
Inventor: MONTGOMERY III WILLIE
IPC: G06Q30/00
Filed: 2021-06-22
Abstract: There are provided systems and methods relating to regulating merchandise received at distribution centers. In one form, the system includes: a distribution center for storing various types of merchandise, and purchase orders for projected incoming merchandise to be delivered on projected delivery dates from vendors to the distribution center. The system also includes a control circuit configured to: receive a merchandise capacity limit for one or more storage areas for a future target date; determine a projected amount of merchandise present at the storage area(s) for the future target date; compare the projected amount of merchandise to the merchandise capacity limit; if the projected amount of merchandise does not exceed the limit, transmit the purchase orders to the corresponding vendors; and if the projected amount of merchandise exceeds the limit, apply prioritization criteria to adjust some of the purchase orders and defer the projected delivery dates for those purchase orders.
Patent WO-2022016043-A1 (WO)
Title: Conjugated oligonucleotides for tissue specific delivery
Inventor: KHVOROVA ANASTASIA
IPC: A61K48/00
Filed: 2021-07-16
Abstract: Provided herein are conjugated oligonucleotides that are characterized by efficient and specific tissue distribution with enhanced  in vivo  silencing efficacy.
Patent WO-2022035582-A1 (WO)
Title: Systems and methods for determining a network path trace
Inventor: LIU JIANDA
IPC: H04L12/26
Filed: 2021-07-27
Abstract: In one embodiment, a method includes receiving, by a network orchestrator, trace parameters from a user device. The method also includes determining, by the network orchestrator, to initiate a network path trace for the application, generating, by the network orchestrator, a filter policy for the network path trace using the trace parameters, and allocating, by the network orchestrator, a trace identification to the network path trace. The method also includes initiating, by the network orchestrator, the network path trace within a network by communicating the filter policy and the trace identification to a first node of the network and receiving, by the network orchestrator, network path trace data from a plurality of nodes of the network. The method further includes generating, by the network orchestrator, a trace report for the application using the network path trace data.