baber/WOPTO huggingface dataset:
Patent AU-766801-B2 (AU)
Title: Cyclothiocarbamate derivatives as progesterone receptor modulators
Inventor: ZHANG PUWEN
IPC: C07D265/18
Filed: 2000-05-01
Granted: 2003-10-23
Abstract: 1. Technical Result Increase in efficiency of treatment of progesterone-related maladies.         2. Essence The present invention provides compounds wherein R1 and R2 are independent substituents selected from the group of H, optionally substituted C1 to C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3 to C8 cycloalkyl, aryl, heterocyclic groups, or CORA or NRBCOR; or R1 and R2 are fused to form an optionally substituted 3 to 8 membered Spiro cyclic ring or a Spiro cyclic ring containing one to three heteroatoms selected from O, S and N; RA is selected from H, amino, or optionally substituted C1 to C3 alkyl, aryl, C1 to C3 alkoxy, or C1 to C3 aminoalkyl groups; R8 is H, C1 to C3 alkyl, or substituted C1 to C3 alkyl; R3 is H, OH, NH2 or optionally substituted C1 to C6 alkyl, C3 to C6 alkenyl, or alkynyl groups; RC is selected from H or optionally substituted C1 to C3 alkyl, aryl, C1 to C3 alkoxy, or C1 to C3 aminoalkyl groups; Q1 is S, NR7; or CR8R9, R5 is an optionally trisubstituted benzene ring or an optionally substituted five or six membered heterocyclic ring with 1, 2, or 3 ring heteroatoms selected from the group of O, S, SO, SO2 or NR6; or a pharmaceutically acceptable salt thereof, as well as methods of using these compounds for contraception and the treatment of progesterone-related maladies.         3. Field of Application Medicine.
Patent AU-686569-B2 (AU)
Title: Improved method for detection of specific target cells in specialized or mixed cell population and solutions containing mixed cell populations
Inventor: FODSTAD OYSTEIN
IPC: C12N5/071
Filed: 1993-09-10
Granted: 1998-02-12
Abstract: The invention relates to a method for detecting specific target-cells in a simple and time saving way, using paramagnetic particles, antibodies recognizing the Fc portions of target-cell associating antibodies and target-cell associating antibodies directed to specific antigen determinants in the target-cell membranes. Incubation of the cell suspension with a mild detergent and/or second set of antibodies or antibody fragments, prelabeled or not with fluorescent agents, metallocolloids, radioisotopes, biotincomplexes or certain enzymes allowing visualization, with dramatically increase the specificity of the method. The method can further be used for isolation of the target-cells by magnetic field application and kit for performing the method according to the invention is described.
Patent AU-729653-B2 (AU)
Title: Vinyl-pyrrolidinone cephalosporins with basic substituents
Inventor: ANGEHRN PETER
IPC: C07D501/06
Filed: 1997-12-18
Granted: 2001-02-08
Abstract: The present invention relates to cephalosporin derivatives of the general formula <CHEM>  wherein   X   is CH or N; R<1>   is hydrogen or cyclopentyl; R<2>   is a group of formula <CHEM>   R<3>   is hydrogen, an alkalimetal ion or a tertiary ammonium group; R<4>   is hydrogen, an amino protecting group, pyrrolidin-2-ylmethyl, azetidin-3-ylmethyl, iminomethyl, 1-carbamimidoyl; R<5>   is hydrogen, dialkylcarbamoyl,  omega -hydroxyalkyl,  omega -aminoalkyl, pyridinium-1-ylmethyl, 1-hydroxy-3-aminomethyl-propyl or (hydroxy)-(pyrrolidin-2-yl)methyl; R<6>   is hydrogen, trifluoromethyl or hydroxy; and R<7>   is alkyl,  omega -hydroxy-alkyl, cycloalkyl, 3-pyrrolidinyl, 3-azetidinyl, iminomethyl or 1-carbamimidoyl; as well as readily hydrolyzable esters thereof, pharmaceutically acceptable salts of said compounds and hydrates of the compounds of formula I and of their esters and salts; the invention is further concerned with the manufacture of compounds of formula I; with their use as pharmaceutically active substances, particularly for the treatment and prophylaxis of infectious diseases, and with pharmaceutical preparations containing a compound of formula I for the treatment and prophylaxis of infectious diseases.
Patent AU-531714-B2 (AU)
Title: Prostaglandin derivatives of the delta2,4-11-deoxy-peg series
Inventor: BARTMANN WILHELM
IPC: C07D407/12
Filed: 1979-07-06
Granted: 1983-09-01
Abstract: The present invention relates to novel prostaglandin derivatives of the formula I    <IMAGE>  I  which are structurally related to the naturally occurring prostaglandins and in which R1 denotes (a) hydrogen or a straight-chain or branched, saturated or unsaturated aliphatic or cycloaliphatic hydrocarbon radical having up to ten carbon atoms or (b) a physiologically acceptable metal or NH4 ion or an ammonium ion which is derived from a primary, secondary or tertiary amine and R2 denotes a straight-chain, aliphatic hydrocarbon radical having up to six carbon atoms and to a process for their manufacture. The compounds of the invention are distinguished in particular by gastric acid secretion-inhibiting and ulcer-protective properties.
Patent AU-755854-B2 (AU)
Title: Radio communications unit
Inventor: BRISTOW ROBERT OWEN
IPC: C12N15/54
Filed: 1999-07-05
Granted: 2002-12-19
Abstract: There is described a radio communications system, including a unit which is able to communicate over a radio communications network such as a satellite or cellular system, and is also able to communicate with a device such as a portable handset over a short range radio link. In order to avoid potentially troublesome interference on the communications path with the communications network, the unit is able to detect the strength of signals received on the short range radio link, and alert the user if those signals are such as to be a potential source of interference.
Patent AU-660567-B2 (AU)
Title: Unshaped alumina spinel refractory
Inventor: YAMAMURA TAKASHI
IPC: C04B28/06
Filed: 1993-11-03
Granted: 1995-06-29
Abstract: An unshaped alumina spinel refractory excellent in spalling, corrosion and slag resistances, which comprises an alumina spinel clinker having a molar ratio of MgO to Al<6>O<7> of 0.14:1.86 to 0.6:1.4, optionally together with spinel clinker with an approximately theoretical composition based on the alumina spinel clinker, and the balance of sintered alumina and alumina cement. It is possible to suppress the extension of crack by adding crushed alumina particles with a particle size of 10 to 50 mm to the refractory. <IMAGE>
Patent AU-783829-B2 (AU)
Title: A reclinable chair
Inventor: STEWART ROBERT BRUCE
IPC: A47C3/025
Filed: 2001-06-28
Granted: 2005-12-08
Abstract: An arm assembly (24) is provided for a chair (12). The chair (12) has a forward direction and a rearward direction. The arm assembly (24) comprises an armrest (26) and a support structure (28). A mounting device movably mounts the armrest to the support structure. The mounting device constrains the movement of the armrest (26) relative to the support structure to movement in a substantially horizontal plane having two degrees of freedom defined by first and second transversely arranged axes lying within the substantially horizontal plane. The armrest (26) thus move in a substantially planar fashion without changing the orientation of the armrest (26).
Patent AU-557395-B2 (AU)
Title: Preparation of thieno-imidazole derivatives
Inventor: GRUETZMACHER GORDON DWIGHT
IPC: C07D495/04
Filed: 1986-03-13
Granted: 1986-12-18
Abstract: A process for the preparation of a thieno-imidazole derivative having the general formula:-werein R is -(CH<sub>2</sub>)<sub>4</sub>CH<sub>3</sub>, -(CH<sub>2</sub>)<sub>3</sub>OR<sup>1</sup> or -(CH<sub>2</sub>)<sub>5</sub>0R<sup>1</sup>, R' is (C<sub>1</sub>-C<sub>6</sub>) alkyl, -(CH<sub>2</sub>)<sub>4</sub>CN or -(CH<sub>2</sub>)<sub>4</sub>COOR<sup>2</sup> and R<sup>2</sup> is (C<sub>1</sub>-C<sub>6</sub>) alkyl or phenyl; characterized in that a compound of the formula:-wherein R is as defined above, is reacted with an epoxy compound of the formula:-wherein R<sup>3</sup> is hydrogen, methyl or-CH<sub>2</sub>OH; in the presence of an alkanol.In particular this process may be used to prepare descarboxybiotin which is a useful intermediate for the preparation of d - biotin.
Patent AU-584186-B2 (AU)
Title: Delamination-resistant cellular retroreflective sheeting
Inventor: BERGESON DAVID LYNN
IPC: G02B5/128
Filed: 1986-04-16
Granted: 1989-05-18
Abstract: An improved, delamination-resistant, cellular retroreflective sheeting comprising: 1) base sheet having a layer of retroreflective elements disposed over one of its surfaces, 2) a polymeric cover film disposed in spaced relation from the layer of retroreflective elements, and 3) a network of narrow intersecting bonds extending between said cover film and base sheet to adhere the cover film and base sheet together and form a plurality of cells within which retroreflective elements are hermetically sealed. The cover film, which comprises a continuous polymeric phase and a discontinuous polymeric phase, is biaxially oriented such that the discontinuous polymeric phase is in the form of minute disks distributed substantially uniformly througout the film. The retroreflective sheeting is resistant to delamination because under the influence of forces that tend to remove the cover film from the base sheet, the cover film is generally removed only at the edge of the sheeting, e.g., from the front row of cells, but no further. Most of the sheeting remains intact and ready for continued utility.
Patent AU-683634-B2 (AU)
Title: Glaucoma treatment
Inventor: LIPTON STUART A
IPC: A61K31/00
Filed: 1993-12-06
Granted: 1997-11-20
Abstract: Elevated glutamate levels are associated with glaucoma, and damage to retinal ganglion cells can be controlled by administering to the patient a compound capable of reducing glutamate induced excitotoxicity in a concentration effective to cause reduction of such excitotoxicity.
Patent AU-672869-B2 (AU)
Title: Purification of polysaccharides
Inventor: KASICA JAMES
IPC: A23L5/20
Filed: 1994-03-23
Granted: 1996-10-17
Abstract: A steam-stripping process suitable for the removal of impurities from polysaccharides, including soluble starch hydrolysates, is disclosed herein. This process may be used in combination with other purification processes, such as ultrafiltration, ion exchange processes or treatment with activated carbon, as well as with a bleaching process. Soluble starch hydrolysates may also be purified by a combination of ultrafiltration and bleaching or by a combination of activated carbon treatment and bleaching. In these processes, the polysaccharide or the soluble starch hydrolysate that is produced is bland in flavor, free of off-odor, optionally, lighter or white in color and suitable for use in food systems requiring these characteristics. Other purification process combinations which are disclosed for removal of undesirable flavors, odors and colors from polysaccharides include:     1. Ultrafiltration and carbon treatment;   2. Ultrafiltration and steam-stripping;   3. Steam-stripping and carbon treatment;   4. Ion exchange treatment and ultrafiltration;   5. Ion exchange treatment and steam-stripping; and   6. Ion exchange treatment and carbon treatment.   A bleaching process may precede any of these processes. If ozone or a peroxide is employed, the bleaching step may follow any of these processes. Any of the processes may be combined with other processes disclosed herein to provide additional purification measures. The processes are particularly useful for purification of low molecular weight soluble polysaccharide hydrolysates, such as dextrins. These purified polysaccharides are used to improve foods and pharmaceutical products.
Patent AU-746936-B2 (AU)
Title: Improvements to waste water treatment using activated sludge process
Inventor: BUJON BRUNO
IPC: C02F3/12
Filed: 1999-09-29
Granted: 2002-05-09
Abstract: Process for controlling the retention time of the sludge undergoing clarification in a process for treating wastewater by activated sludge comprising a recirculation of the activated sludge from the clarification stage into the biological basins, characterized in that the rate of sludge recirculation (Qr) is varied so as to maintain a constant recirculated sludge concentration (Cr) while at the same time guaranteeing a retention time (RT) of the sludge undergoing clarification of less than a critical value (RTmax).
Patent AU-642149-B2 (AU)
Title: Targeted liposomes and methods for liposome-protein coupling
Inventor: LOUGHREY HELEN C
IPC: A61K47/48
Filed: 1990-06-22
Granted: 1993-10-14
Abstract: This invention relates to a method for synthesizing a substantially pure reactive lipid including, for example, N-[4-(p-maleimidophenyl)-butyryl]phosphatidylethanolamine (MPB-PE) and related compositions. The compositions of the present invention are useful as coupling agents and may be incorporated into liposomes and subseuquently coupled to proteins, cofactors and a number of other molecules. A preferred coupling method is also disclosed as are protein conjugates. The present invention also relates to a general method for producing sized protein-liposome conjugates exhibiting enhanced blood circulation times. The present invention also relates to the sized protein-liposome conjugate compositions produced by the method of the present invention. The protein-liposome conjugates of the present invention preferably range in size from about 75 nm to about 200 nm. The liposomes of the invention may have a trans-membrane potential across their membranes, and may be dehydrated. In addition, the composition may contain ionizable bioactive agents such as antineoplastic agents, and may be used in diagnostic assays.
Patent AU-583774-B2 (AU)
Title: Device for the metering of a chemical, particularly for seed treatment
Inventor: MORRIS DAVID BRANDON
IPC: B67D3/00
Filed: 1986-07-24
Granted: 1989-05-04
Abstract: To avoid internal and external soiling in a device for the metering of chemicals, particularly for seed treatment, a special storage system unit (1) is provided which can be loaded with disposable packages (3a, 3b, 3c) which are connected by means of couplings (15) to a supply line (19) leading to an atomiser (65), in which arrangement a metering unit (48) is arranged in the supply line (19) and the entire liquid-carrying system from the packages (3a, 3b, 3c) to the atomiser (65) is closed off to the working environment.
Patent AU-678820-B2 (AU)
Title: Pipe coupling
Inventor: WEBB IAN RICHARD
IPC: F16L21/00
Filed: 1994-05-03
Granted: 1997-06-12
Abstract: PCT No. PCT/GB91/01232 Sec. 371 Date Jan. 26, 1993 Sec. 102(e) Date Jan. 26, 1993 PCT Filed Jul. 23, 1991 PCT Pub. No. WO92/02752 PCT Pub. Date Feb. 20, 1992.A pipe coupling for connecting together two plain-ended pipes in a fluid-tight manner comprises an outer tubular casing, an inner tubular casing and a tubular sealing sleeve. The sealing sleeve has two sets of inwardly projecting ribs which, in use, are pressed into sealing engagement with the respective ends of the pipes. The inner and outer casings are longitudinally split and tensioning screws on the outer casing can be tightened to tighten the outer casing around the inner casing and the sealing sleeve. Frustoconical slots in the outer surfaces of the sealing sleeves receive frustoconical gripping rings which have gripping teeth on the inner sides which bite into the pipe surfaces to secure the pipes against axial displacement.
Patent AU-595232-B2 (AU)
Title: Substituted 2-cyano-2-phenyl ethyl-amine
Inventor: CHAMBERS PAMELA ANNE
IPC: C07C69/734
Filed: 1986-09-02
Granted: 1990-03-29
Abstract: Compounds of the formula: 
<CHEM>
 in which X is hydrogen or hydroxy; a process for their preparation; intermediates useful in their preparation; pharmaceutical compositions containing them; and their use in therapy as inhibitors of dopamine- beta -hydroxylase activity in mammals.
Patent AU-644094-B2 (AU)
Title: Medicaments
Inventor: PALMER JAMES BARRY DOUGLAS
IPC: A61P11/00
Filed: 1990-09-07
Granted: 1993-12-02
Abstract: Pharmaceutical compositions comprising effective amounts of salmeterol (and/or a physiologically acceptable salt thereof) and beclomethasone dipropionate as a combined preparation for simultaneous, sequential or separate administration by inhalation in the treatment of respiratory disorders.
Patent AU-639940-B2 (AU)
Title: A reagent for the detection of fibrinolytic activity
IPC: G01N33/577
Filed: 1990-08-16
Granted: 1993-08-12
Abstract: A diagnostic reagent for the detection in vivo of increased release of a fibrinolytic enzyme or increased fibrinolytic activity in the human or animal body comprises an antibody reactive with a fibrinolytic enzyme, or a biologically active fragment of the antibody, labelled with a substance which permits the detection in vivo of binding of the antibody to the fibrinolytic enzyme. In one embodiment, increased clearance of the antibody is provided by subsequent administration of the fibrinolytic enzyme with which the antibody is reactive. The fibrinolytic enzyme is preferably t-PA.
Patent AU-686516-B2 (AU)
Title: Fuel injection system for combustion-powered tool
Inventor: ROBINSON JAMES W
IPC: B25C1/08
Filed: 1996-08-28
Granted: 1998-02-05
Abstract: A fuel system is provided for a combustion-powered tool (10) having a self-contained internal combustion power source (16) with a combustion chamber (62), and constructed and arranged for driving a drive blade (88) to impact a fastener (N) and drive it into a workpiece. The tool (10) includes a housing (12) having a main chamber (14) enclosing the power source (16) and having a first end (28) adjacent a nosepiece (76) wherein the fasteners (N) are positioned prior to driving, and a second end (34) opposite the first end (28) and adjacent the combustion chamber (62). A fuel cell chamber (18) is in communication with the main chamber (14) and has a first chamber end (28) corresponding to the first end (28) of the main chamber (14) and a second chamber end (40) corresponding to the second end (34) of the main chamber (14). A fuel metering valve (44) is disposed in the fuel cell chamber (18) at the first end (38) so that a fuel cell (50) having a fuel outlet end (52) operationally inserted into the fuel cell chamber (18) will engage the valve (44) so that fuel is dispensed into the valve in a location closer to the first chamber end (38) than to the second chamber end (40). <IMAGE>
Patent AU-680496-B2 (AU)
Title: Novel bisoxadiazolidine derivative
Inventor: NIIGATA KUNIHIRO
IPC: A61P3/10
Filed: 1994-04-26
Granted: 1997-07-31
Abstract: A bisoxadiazolidinedione derivative of general formula (I) useful as an insulin-sensitivity improver, a pharmaceutically acceptable salt thereof, and a medicinal composition thereof, wherein (a) and (b) may be the same or different from each other and each represent an optionally substituted phenylene group, and L represents: (1) an oxygen atom, (2) a group of formula (II) (R<1> being a hydrogen atom or a lower alkyl group), (3) a group of the formula: -S(O)n- (n being 0, 1 or 2), (4) a group of the formula: -CO-, (5) a group of formula (III) or (IV) (R<2> being a hydrogen atom or a lower alkyl group), or (6) an alkylene or alkenylene group which may be substituted and interrupted by an oxygen atom and/or a sulfur atom, and the like. <CHEM>
Patent AU-536682-B2 (AU)
Title: Refrigerating liquid batches
Inventor: SMITH MICHAEL VAN BREDA
IPC: F25D31/00
Filed: 1981-01-22
Granted: 1984-05-17
Abstract: Liquid is cooled in a batch mode. A batch of liquid is circulated in a cooling loop (12) until <sup>i</sup>tjs cooled to a desired temperature at which time it is removed from the cooling loop (12) and a new batch is introduced therein. Preferably, the cooled batch is discharged from the cooling loop by the new batch with as little mixing as practicable. The cooling loop has a desired volume determined by a receiver (36) of suitable capacity. A supply accumulator (14) is used to accumulate liquid to be cooled and from which liquid to be cooled is supplied into the cooling loop. Cooled liquid is discharged from the cooling loop into a product accumulator (16). The liquid may be cooled to a temperature close to its freezing point by freezing a minor portion of the liquid in the cooling loop which is then melted by the liquid of the next batch when it is introduced into the cooling loop. The cooling loop is such as to promote plug flow and to reduce backmixing. In a preferred form, the cooling loop has an evaporative cooler (32) which utilises a suitable refrigerant. The refrigerant is evaporated in each cooling cycle, at a progressively reducing pressure and temperature achieved by withdrawing liquid refrigerant from a closed first vessel (92), evaporating it in the cooler (32) to cool the liquid, compressing the vapour refrigerant by means of a compressor (76), condensing the vapour refrigerant in a condenser (80) and feeding the condensate into a further vessel (94). The liquid refrigerant is withdrawn initially into a flash tank (70), vapour being circulated by a pump (72) to the cooler (32). Valves (88,90,100 and 102) are provided to switch the two vessels (92, 94) around at the end of each cooling cycle.
Patent AU-582036-B2 (AU)
Title: Anaerobic pasteurizing conditioning system
Inventor: WHITE RICHARD L
IPC: A23L7/10
Filed: 1986-12-23
Granted: 1989-03-09
Abstract: An anaerobic, pasteurizing conditioning system for treating matter such as whole and ground grain and minerals to increase the rate of conversion during digestion and thus the nutritional value thereof. The system comprises a direct fired steam generator adapted for producing treatment fluid comprising steam and non-condensible gases, the gases containing insufficient oxygen for substantial aerobic bacterial growth. The steam and oxygen deficient non-condensible gases are discharged into the vessel for counter-current flow relative to matter passing therethrough. The operation of the direct fired steam generator is controlled for producing a sufficiently large volume of oxygen deficient gases and steam for purging the matter of other gases flowing therewith and maintaining the deficient oxygen level in the non-condensible gases for creating an anaerobic condition. In this manner an improved feedstuff is provided wherein the starch components have first been gelatinized in a heated, anaerobic environment and thereafter fractionated to render the feedstuff more digestible.
Patent AU-725249-B2 (AU)
Title: Use of a thienotriazolodiazepine to increase apolipoprotein A-I levels
Inventor: KEMPEN HERMAN
IPC: A61K31/55
Filed: 1996-08-30
Granted: 2000-10-12
Abstract: PCT No. PCT/EP96/03814 Sec. 371 Date Feb. 23, 1998 Sec. 102(e) Date Feb. 23, 1998 PCT Filed Aug. 30, 1996 PCT Pub. No. WO97/09048 PCT Pub. Date Mar. 13, 19979-methyl-4-phenyl-6H-thieno[3,2-f]-s-triazolo[4,3-a][1,4]diazepine for the treatment and prevention of illnesses which are caused by low plasma apolipoprotein A-I levels as coronary coronary disease.
Patent AU-679239-B2 (AU)
Title: Method of servicing interior of large container and service apparatus
Inventor: NIEKERK ERASMUS VAN
IPC: E04G3/30
Filed: 1994-08-10
Granted: 1997-06-26
Abstract: A method and apparatus of servicing an interior of a large container (12;112) having a narrow access opening (14;114) comprising inserting a service apparatus (10;110) in a collapsed condition through the access opening (14;114), deploying the service apparatus (10,110) when within the container interior into an operative condition such that extremities of the apparatus extend toward a wall (16;116) of the container and performing a service operation on an internal wall surface (18;118) of the container while supported on the apparatus at a position toward one of said extremities. <IMAGE>