baber/WOPTO huggingface dataset:
Patent CA-2274381-C (CA)
Title: Therapeutic combinations comprising a selective estrogen receptor modulator and prostaglandin e2
Inventor: THOMPSON DAVID DUANE
IPC: A61K31/445
Filed: 1999-06-14
Granted: 2004-02-10
Abstract: This invention is directed to pharmaceutical combination compositions and methods comprising (-)-cis-6-phenyl-5-(4-(2-pyrrolidin-1-yl-ethoxy)-phenyl)-5,6,7,8-tetrahydronaphthalene-2-of or a pharmaceutically acceptable salt thereof and PGE2 or a pharmaceutically acceptable salt thereof, methods of using such compositions and kits containing such compositions. The compositions are useful for treating musculoskeletal frailty, including osteoporosis, osteoporotic fracture, low bone mass and frailty.
Patent CA-2279088-C (CA)
Inventor: NISHIGUCHI TSUTOMU
IPC: A01P3/00
Filed: 1999-07-29
Granted: 2003-04-01
Abstract: The present invention relates to a fungicidal composition obtained by mixing a 1,2,3-thiadiazole derivative of general formula (I) useful as a plant disease controller with at least one fungicide selected from the compounds having a fungicidal activity against plant diseases, and to a method for using the same:    wherein R1 is hydrogen, alkyl or cycloalkyl and R2 is CO-Y-R1, wherein Y is O, S, NR4 or the like and R3 is hydrogen, alkyl, phenyl, 5- or 6-membered heterocycle or the like.
Patent CA-2282172-C (CA)
Inventor: VAN TOEVER J WAYNE
IPC: B01J19/30
Filed: 1999-09-10
Granted: 2004-11-30
Abstract: Disclosed is a bioreactor apparatus having a bed of buoyant media pellets floating within a filtrate to be processed. The apparatus includes a tank having a peripheral wall for containing filtrate and a bed of media pellets. A central manifold is rotatably supported within the tank, the central manifold being mounted for rotation about a vertical axis and having a plurality of longitudinally spaced openings intermediate its ends, the openings adapted to eject filtrate in a generally horizontal direction and along a substantially vertical plane toward the wall of the tank, cyclically fluidize pellets in a directly narrow zone. In a preferred aspect, there is also a thrust manifold, generally parallel to the axis of the central manifold and having a plurality of longitudinally spaced openings intermediate its ends directed horizontally and generally perpendicularly to the plane. The thrust manifold is supported in association with the central manifold inwardly adjacent the tank wall and offset rearwardly of the plane to rotate with the central manifold. Filtrate is fed to the central manifold and the thrust manifold, whereby the plane of filtrate ejected by the central manifold fluidizes a vertical zone of pellet media around and in front of the thrust manifold and rotation of the central manifold and thrust manifold is caused by filtrate ejected from the openings in the thrust manifold. The invention also comprehends specially designed pellet media for optimum performance. The manifolds may be structured for retrofitting in existing bioreactors.
Patent CA-2282354-C (CA)
Inventor: MEYER HEINRICH
IPC: G01N37/00
Filed: 1998-02-17
Granted: 2009-11-03
Abstract: Known chemical microreactors for chemical synthe-sis and methods for producing have disadvantages such as high production costs or poor flexibility as regards adap-tation to different applications. The invention relates to microreactors and production methods which do not have these disadvantages. Said microreactors are characterized in that the reactors comprise fluid channels on at least one level, as well as fluid inlets and outlets. Said fluid channels are delimited by opposing side walls made of metal and by additional side walls made of metal or plastic which extend between said side walls. The levels are connected to each other and/or to a sealing segment closing off open fluid channels by means of suitable soldered or adhesive layers. The production methods are characterized by production steps in which the individual reactors levels, manufactured by means of galvanization techniques, are connected to each other by soldering or adhesion.
Patent CA-2287714-C (CA)
Title: Protected keepalive message through the internet
Inventor: MAMROS SHAWN
IPC: H04L12/12
Filed: 1999-10-28
Granted: 2007-10-23
Abstract: A method and apparatus for determining the reachability of a remote computer from a local computer through a secured communications link through the Internet. In one embodiment, the secured ISAKMP/Oakley communications link is established between a remote computer and a local computer through the Internet. A protected keepalive message is transmitted by the local computer to the remote computer in the event that the communications link has been idle for a period of time. The protected keepalive message is not a re-key request by the local computer to renegotiate the policy/key(s) of the secured communications link to the Internet. In one embodiment, the protected keepalive message is a protected ISAKMP/Oakley command to which a protected acknowledgement must be supplied. If a protected acknowledgement is received from the remote box by the local box in response to the protected keepalive message, then it is assumed that the remote box is still reachable. However, if the protected acknowledgement is not received from the remote box in response to the protected keepalive message, then it is assumed that their remote box is no longer reachable. In this case, the secured communications link between the remote box and the local box is terminated by the local box.
Patent CA-2290745-C (CA)
Title: Carbamyloxy compounds which inhibit leukocyte adhesion mediated by vla-4
Inventor: SEMKO CHRISTOPHER M
IPC: A61P27/02
Filed: 1998-07-31
Granted: 2009-09-08
Abstract: Disclosed are compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, such as asthma, Alzheimer's disease, atherosclerosis, AIDS dementia, diabete s, inflammatory bowel disease, rheumatoid arthritis, tissue transplantation, tumor metastasis and myocardial ischemia. The compounds can also be administered for the treatment of inflammatory brain diseases such as multiple sclerosis.
Patent CA-2291413-C (CA)
Title: Tamper-indicating closure and method of manufacture
Inventor: GRAHAM PAUL R
IPC: B65D25/20
Filed: 1999-12-02
Granted: 2006-08-08
Abstract: A tamper-indicating closure of integrally molded plastic construction that include a base wall having a peripheral skirt with internal thread for engaging external threads on a container finish. A tamper-indicating band is connected to the edge of the skirt by a plurality of circumferentially spaced integral frangible bridges. A stop flange extends from an edge of the band remote from the skirt for engagement with a bead on the container finish. The stop flange has a circumferentially continuous free edge remote from the band disposed in a plane parallel to the base wall. A plurality of circumferentially spaced openings are disposed in the stop flange adjacent to the band for drainage of liquid from between the closure skirt and the container finish. A plurality of circumferentially spaced gussets in the stop flange are at the free edge of the ring, with each gusset being disposed between an adjacent pair of drainage openings. The gussets function during inversion of the stop flange, from an axially outward orientation as molded to an axially inward orientation for use, to absorb compressive stresses on the flange and thereby isolate portions of the flange surrounding the drainage openings from such compressive stresses. A plurality of circumferentially spaced lugs are molded on the inside surface of the closure for opposed abutment with the bead on the finish to help facilitate drainage from between the skirt and finish.
Patent CA-2294636-C (CA)
Title: Dynamic optical amplifier
Inventor: BALL GARY A
IPC: H04B10/17
Filed: 1998-06-25
Granted: 2004-08-31
Abstract: An optical amplifier for amplifying a plurality of signal components of a mult- wavelength optical beam passing through an optical fiber includes a portion of the optical fiber doped with a rare earth ion to amplify the optical signal wherein the gain spectrum as a function of the wavelength is nonuniform. The optical amplifier further includes a gain flattening module to compensate for the nonuniform gain spectrum of the doped fiber by attenuating each of the channels of the amplified signal to equalize the gain. A gain equalization module compensates for varying gain fluctuations due to the adding and subtracting of signal components. The gain equalization module adjusts dynamically each signal component of the optical beam such that the amplitudes of the signal components are substantially equal, in response to a plurality of control signals. Each control signal is representative of the degree of attenuation required to equalize the signal components. The respective control signals are generated by a loop status monitor that includes a waveguide for demultiplexing the optical beam, and a detector array that determines the amplitude of each signal component. A controller generates the control signals in dependence of the amplitude of the signal components.
Patent CA-2297832-C (CA)
Title: Pellet-type formulation intended for treating the intestinal tract
Inventor: OTTERBECK NORBERT
IPC: A61K9/22
Filed: 1998-04-20
Granted: 2007-09-18
Abstract: An orally adminsterable pharmaceutical pellet formulation for the treatment of the intestinal tract is disclosed, which comprises a core and an enteric coating, the core including, as a pharmaceutical active compound, aminosalicylic acid or a pharmaceutically tolerable salt or a derivative thereof.
Patent CA-2304204-C (CA)
Title: Quinoline-containing .alpha.-ketoamide cysteine and serine protease inhibitors
Inventor: CHATTERJEE SANKAR
IPC: A61K31/445
Filed: 1998-10-07
Granted: 2010-05-18
Abstract: The present invention is directed to quinoline-containing .alpha.-ketoamide inhibitors of cysteine and serine proteases are disclosed. Methods for making these compounds, and methods for using the same are also disclosed.
Patent CA-2309982-C (CA)
Inventor: LUCAORA JOHNNY D
IPC: B23K37/04
Filed: 1998-11-11
Granted: 2008-01-15
Abstract: A vehicle body welding system includes a work station (10) for welding components of a preassembled body (12) with respect to one another. The body (12) is moveable along a fixed path (14) of travel through the work station (10). At least two moveable pillars (18) are located on each side of the fixed path (14) of travel through the work station (10) for synchronized reciprocation between first and second end limits of travel toward and away from the fixed path (14) of travel of the body (12). At least one gate (44) is connectible in a repeatible located position with respect to the moveable pillars (18) on each side of the fixed path (14) for synchronized reciprocation between first and second positions toward and away from the fixed path (14) of travel of the body (12). Locating members (48) are engageable between each pillar (18) and the corresponding gate (44) for locating the gate (44) with respect to the moveable pillar (18) in at least two dimensions.
Patent CA-2318976-C (CA)
Title: Herbicidally active 3-hydroxy-4-aryl-5-oxopyrazoline derivatives
Inventor: GLOCK JUTTA
IPC: A01N43/18
Filed: 1999-03-11
Granted: 2009-10-27
Abstract: Compounds of formula (I), in which the subsituents are as defined in claim 1 , are suitable for use as herbicides, in particular in combination with herbicide-antagonistically effective compounds.
Patent CA-2321024-C (CA)
Inventor: MOSCHEROSCH MICHAEL
IPC: A61L15/46
Filed: 2000-09-27
Granted: 2009-03-03
Abstract: A method of odor control in disposable, absorbent articles is provided using odor control additives comprising phosphorous-containing compounds.
Patent CA-2321687-C (CA)
Title: Combination of a selective nmda nr2b antagonist and a cox-2 inhibitor
Inventor: BOYCE SUSAN
IPC: A61K31/445
Filed: 1999-02-26
Granted: 2008-04-22
Abstract: The present invention provides a combination of a selective NMDA NR2B  antagonist and a COX-2 inhibitor for the treatment or prevention of pain or nociception.
Patent CA-2324746-C (CA)
Inventor: LEEPER ROBERT
IPC: F16H48/30
Filed: 2000-10-30
Granted: 2004-12-28
Abstract: An apparatus and method for demagnetizing a differential which has a controllable electromagnetically actuated clutch. The apparatus includes sensors and a coil connected to a control module. The sensors receive vehicle inputs to indicate various measured values such as vehicle speed, brake pressure, magnetization current provided to the differential, and the like and generates signals which are transmitted to the control module. The control module initiates a demagnetization cycle when certain conditions have been satisfied as indicated by the input signals. The control module provides a DC voltage to the coil to generate magnetic flux for demagnetizing the differential and the components of the differential. In one embodiment a single coil is provided to which is applied both magnetization and demagnetization current.  In another embodiment two coils are provided, one for generating magnetization flux and the other for generating demagnetization flux. The control alternatively applies voltages of reverse polarity in decreasing amplitudes for predetermined periods of time during a demagnetization cycle.
Patent CA-2328408-C (CA)
Title: Zero dead time architecture and method for flow cytometer
Inventor: CHANDLER VAN S
IPC: G01N15/10
Filed: 1999-05-13
Granted: 2005-02-15
Abstract: A method and apparatus for providing a zero dead time for flow analyzers, flow cytometers, and other measurement devices. A circular buffer is used to store data from a flow analyzer in a plurality of data storage areas, until it is convenient to implement more time consuming data processing procedures. User specified parameters, including sampling rate and/or sampling period, size and number of data storage areas, size of the circular or other buffer, signal-to-noise threshold, order of processing when a plurality of Digital Signal Processors (DSPs) is used, and fixed trailing distance, are used to provide flexible and convenient operation by a user. The probability of missing a rare event occurring within the laser beam or other light beam of a flow analyzer or other measurement device is reduced to zero. Functional equivalents may be used in place of the circular buffer, for example, First In-First Out buffers which route data to a cache for potential re-reading and/or reprocessing or additional processing of data, cascading buffers, etc. Circular and functionally equivalent buffers permit sophisticated data processing in which preceding data (for example, data not meeting the S/N threshold) subsequently are re-analyzed for the possibility that the data ar e part of a developingevent peak, such as a developing shoulder thereof, or part of a declining peak. In addition, logic and algorithms to permit re-examination and potential reprocessing of "old" subthreshold data is utilized to improve the SIN ratio of an event peak.</SD OAB>
Patent CA-2334247-C (CA)
Title: Method and system for monitoring broadband quality of services
Inventor: PROCANIK MICHAEL J
IPC: H04J3/14
Filed: 1999-06-03
Granted: 2008-09-02
Abstract: A method and system for monitoring a first virtual circuit in an asynchronous transmission mode (ATM) network comprises the steps of establishing in the network a second virtual circuit with the same path and QoS parameters as the first virtual circuit, and monitoring the first virtual circuit by determining the QoS parameters of the second virtual circuit. Specifically, a monitoring station (100A, 100B) determines the QoS parameters of the second virtual circuit by inserting monitoring information in cells transmitted and received on the second virtual circuit. The monitoring station (100A, 100B) inserts the monitoring information immediately before transmitting each cell and immediately after receiving each cell. Furthermore, the monitoring station (100A, 100B) compares the QoS parameters of the second virtual circuit with the QoS parameters of the first virtual circuit to determine network alarm information.
Patent CA-2335048-C (CA)
Title: Pates contenant des agents de matage et de structuration et produits de revetement les contenant
Inventor: BERSCHEL GUNTER
IPC: C09D7/80
Filed: 2000-03-23
Granted: 2008-02-26
Abstract: L'invention concerne des pâtes contenant des agents de matage et/ou des additifs conférant une structure. Ces pâtes contiennent A) 5 ) 30 % en poids d'au moins un copolymère (méth)acrylique thixotropique et/ou d'au moins un polyester thixotropique ; B) 15 à 45 % en poids d'au moins un agent de matage et/ou de structuration ; C) 30 à 65 % en poids d'au moins un solvant organique ; éventuellement des agents mouillants et dispersants, des agents rhéologiques, des catalyseurs et éventuellement d'autres additifs et auxiliaires. L'addition des proportions des composantes A), B) et C) donne 100 % en poids et le rapport en poids copolymère (méth)acrylique thixotropique et/ou polyester thixotropique/agent de matage et/ou de structuration est de 1 : 6 à 1 : 0,8.
Patent CA-2335355-C (CA)
Inventor: PROCIW LEV A
IPC: F23R3/34
Filed: 1999-07-06
Granted: 2008-10-14
Abstract: The igniter for the combustor in a gas turbine engine includes a tubular member extending beyond the igniter tip, wherein the tubular member is a porous ceramic or high temperature nickel alloy. Fuel is fed to the bore of the tubular member by capillary action through the porous material of the tubular member and air passes through the porous tubular member to the bore.
Patent CA-2337336-C (CA)
Title: Nutating fluid delivery apparatus
Inventor: CLEARMAN JOSEPH H
IPC: B05B1/18
Filed: 1999-07-14
Granted: 2012-01-24
Abstract: The present invention provides an apparatus comprising: a body having a fluid inlet (550); a wobble turbine (554) disposed downstream of the fluid inlet, the wobble turbine being configured to rotate when struck by a stream emitted from the fluid inlet; and a fluid redirecting means (567), such as a moving or stationary shroud or a chamber, disposed downstream of the wobble turbine to redirect the stream. While the wobble turbine may be placed downstream of the fluid inlet in various ways, it is preferred that the wobble turbine is disposed in an axially spaced relationship to the fluid inlet, such as by coupling the wobble turbine to the body in a loose, post and sleeve relationship. The preferred wobble turbine includes a convex conical upper surface (558), with angular momentum inducing members formed therein/thereon, wherein the angular momentun inducing members are selected from grooves, vanes, blades (560) and combinations thereof. The apparatus may further comprise a wobble limiting member, such as a stator ring, engaging the wobble turbine.
Patent CA-2340861-C (CA)
Title: Aerosol spray gun
Inventor: HASHIMOTO SHIGEFUMI
IPC: B05B7/12
Filed: 2001-03-14
Granted: 2005-05-17
Abstract: An aerosol spray gun used selectively in two spraying modes of small pattern and large pattern and is provided which can be comprised of simple components. Aerosol spray gun 1 includes a throttle valve mechanism 35, an air duct 43, and a coupling link 45. The throttle valve mechanism 35 is provided in an internal air duct 23 for supplying pressurized air to a patterning air outlet 21 which shapes a paint spraying stream jetted out from the aerosol spray gun 1, and it has a movable valve element 39 to which a compressed spring 41 applies force to open the valve. The air duct 43 created at the tip of the movable valve element 39 supplies a small volume of air from the internal air duct 23 to the patterning air outlet 21 while the movable valve element 39 seats on a value seat 37. The coupling link 45, coupling the movable valve element 39 to the trigger 7, is provided with an elongated hole 47 to disconnect the trigger 7 from the movable valve element 39 without cooperative relation between them from an initial stage where an operator begins to squeeze the trigger 7 to an intermediate stage before the operator fully squeezes the trigger.
Patent CA-2343254-C (CA)
Inventor: MARCHILDON TED
IPC: A01G9/00
Filed: 2001-04-05
Granted: 2002-03-26
Abstract: A rotary plant growing apparatus has an open-ended cylindrical drum which rotates about a horizontal axis on a support stand. A lamp is positioned at the axis of the drum. Holes in the drum hold plant pots, with the plants facing the light and the bottom of the pots extending radially outward from the drum. A tray under the drum holds a pool of water and is spaced from the drum such that the lower part of the pots contacts the water as the drum rotates, watering the plants. The apparatus is particularly suitable for hydroponic gardening.
Patent CA-2349672-C (CA)
Inventor: DUPUIS DOMINIQUE
IPC: A61K8/40
Filed: 1999-10-27
Granted: 2005-03-08
Abstract: The invention concerns a method for preparing mineral capsules consisting of aqueous liquid core enclosed in mineral coating, said method consisting in: 1) emulsifying an aqueous fluid in a phase non-miscible with said aqueous fluid so as to disperse it therein in the form of droplets; 2) contacting, in the resulting emulsion, at least a zirconium, silicon, aluminium and/or a transition metal capable of being hydrolysed or subjected to condensation polymerisation in temperature and pH conditions suitable for forming a precipitate consisting of the corresponding oxide or hydroxide; 3) recuperating the resulting mineral capsules and, if required, purifying them. Said method is characterised in that the formation of the mineral precipitate in the second step is carried out in the presence of an amphiphilic surfactant system present in the emulsion and capable of concentrating the deposit of mineral particles of said precipitate formed in the interface of the aqueous droplets and the hydrophobic phase and of effectively blocking their diffusion inside the droplets.
Patent CA-2350815-C (CA)
Inventor: ZADEI JAVAD M
IPC: A61K31/66
Filed: 1999-11-15
Granted: 2008-10-07
Abstract: The present invention relates to sterile, stable dosage forms suitable for reconstitution and parenteral administration to a patient, said dosage form comprising an amorphous aminoalkyl dihydrogen phosphorothioate, and amifostine in particular. The invention further relates to a method of preparing such a dosage form, which typically exhibits enhanced thermal stability as compared to existing vacuum dried amorphous amifostine.
Patent CA-2351097-C (CA)
Inventor: BERMAN LAWRENCE
IPC: G07F17/24
Filed: 2001-06-20
Granted: 2005-01-04
Abstract: A parking meter consisting of a housing and a stanchion located adjacent a parking space for mounting of the parking meter thereon. The stanchion has a tubular upper end portion and the parking meter has a tubular lower end portion for positioning around the upper end of the stanchion A fitting is attached to the upper end of the stanchion and gear teeth are defined by the fitting. The lower end of the meter housing has formed therein a set of gear teeth adapted to mesh with the gear teeth of the fitting in any one of several available relative positions. A  bolt and pin combination is employed for providing a high security connection of the fitting and upper housing to the stanchion. Passages are provided so that rainwater and the like is directed outside of the housing and stanchion and does not accumulate within the meter housing.