baber/WOPTO huggingface dataset:
Patent CA-3088966-A1 (CA)
Title: Inhibiteurs d'endopeptidase neutre (nep) et d'endopeptidase humaine soluble (hsep) destines a la prophylaxie et au traitement de maladies oculaires
Inventor: TURSKI CHRISTOPHER
IPC: A61K31/675
Filed: 2019-01-31
Abstract: L'invention concerne une nouvelle utilisation de benzazépine, de benzoxazépine, d'acide benzothiazépine-N-acétique et de dérivés de benzazépinone à substituants phosphono, dont l'activité inhibitrice est à la fois celle d'une endopeptidase neutre (NEP) et/ou d'une endopeptidase humaine soluble (hSEP), et celle d'une endothéline convertase (ECE). Les composés de l'invention sont utiles pour la préparation de compositions pharmaceutiques pour la prophylaxie et pour le traitement de maladies oculaires.
Patent CA-3093180-A1 (CA)
Inventor: ARAUJO JOSE
IPC: G06T19/00
Filed: 2018-06-04
Abstract: L'invention concerne un visiocasque (HMD) qui comprend une caméra (101) configurée pour capturer une vidéo d'une scène du monde réel avec un premier champ de vision (FoV) (111), un circuit d'interface de réseau (102) configuré pour transmettre une vidéo à un dispositif d'affichage de réception (140), et un moyen de traitement (103) qui est permet de générer un modèle 3D de la scène du monde réel, et de générer une vidéo à partir du modèle 3D à l'aide d'un second FoV qui est plus large que le premier FoV (111). Le moyen de traitement (103) est en outre conçu pour estimer un mouvement de la caméra (101), et pour transmettre la vidéo générée au dispositif d'affichage de réception (140) si le mouvement estimé de la caméra (101) satisfait une ou plusieurs conditions indiquant un mouvement rapide, sinon, le flux de la vidéo capturée vers le dispositif d'affichage de réception (140). L'invention concerne en outre un procédé mis en uvre par un HMD, un programme informatique correspondant et un support de stockage lisible par ordinateur correspondant.
Patent CA-3093333-A1 (CA)
Inventor: HAY GARY
IPC: F16K31/00
Filed: 2019-03-08
Abstract: L'invention concerne une soupape de mélange thermostatique comprenant un logement de soupape et un dispositif de soupape (navette) augmentant le débit et la régulation de fluide. Le dispositif de soupape reçu par la soupape thermostatique accueillant le dispositif de soupape comporte une première paroi, une seconde paroi espacée et située dans une direction intérieure de la première paroi, un élément de raccordement raccordant la première paroi à la seconde paroi et un passage situé entre la première paroi et la seconde paroi et au moins un passage à travers une ouverture dans la première paroi à travers une ouverture dans la seconde paroi dans une direction intérieure.
Patent CA-3093816-A1 (CA)
Inventor: SNEAG DARRYL B
IPC: A61B5/055
Filed: 2020-09-18
Abstract: Some implementations provide a method for imaging one or more peripheral nerves in a region of a subject, which method includes: introducing a dose of an iron-based agent into the subject, wherein the dose causes a reduction of a T2 relaxation time of the subject' s blood; and acquiring, from a magnetic resonance imaging (MRI) scanner, one or more fluid-sensitive IVIRI images of the region of the subject that has received the dose. The magnetic resonance (IVIR) signals from the subject's blood in the region is substantially reduced in response to the dose of the iron-based agent.
Patent CA-3093840-A1 (CA)
Title: Lymphohematopoietic engineering using cas9 base editors
Inventor: MORIARITY BRANDEN
IPC: A61P31/00
Filed: 2019-03-13
Abstract: Provided herein are methods and systems for targeted gene disruption (knock-out, missense mutation) and targeted gene knock-in in mammalian cells using base editors and guide RNAs (gRNAs) designed to target splice acceptor-splice donor sites. Also provided herein are universally acceptable genetically engineered cells comprising targeted disruptions in immunotherapy-related genes and comprising a CAR/TCR for therapeutic applications.
Patent CA-3098646-A1 (CA)
Inventor: GUAN YAYANG
IPC: H04L29/08
Filed: 2019-11-13
Abstract: Disclosed herein are devices, methods, systems, and apparatus, including computer programs encoded on computer storage media, for managing trust points in ledger systems. One of the methods includes obtaining a request for establishing a trust point for a specified record in a series of records in a ledger system, determining whether the specified record is a candidate trust point that is trustworthy traceable to a preceding trust point, if so, determining whether the specified record is a timestamp record including trust timestamp information from a trust time server, in response to determining the specified record is not a timestamp record, identifying a timestamp record adjacent to the specified record, determining whether the timestamp record is trustworthily traceable to the specified record, and in response to determining the timestamp record is trustworthily traceable to the specified record, marking the timestamp record to be the trust point in the series of records.
Patent CA-3100486-A1 (CA)
Title: Motorcycle conversion kit
Inventor: VAN THUYL ZEGER
IPC: B62K13/00
Filed: 2020-11-24
Abstract: A motorcycle conversion kit for a three wheeled motorcycle wherein the conversion kit of the present invention is operable to transition the motorcycle so as to traverse across a snowy terrain. The conversion kit of the present invention includes a pair of ski assemblies that are operably secured to the front rotor assembly of the motorcycle. The ski assemblies include rotor movement inhibitors. A swing arm assembly is operably coupled to the frame and includes a front portion and a rear portion. The rear portion has rotatably mounted thereto a snow belt drive wheel. The show belt drive wheel is superposed a snow belt of a snow belt assembly wherein the snow belt assembly is secured to the frame of the motorcycle. The kit further includes a fuel cell bracket assembly having support members mounted on opposing sides of the frame and having a compartment rearward of the motorcycle.
Patent CA-3101843-A1 (CA)
Inventor: CHOW WILLIAM WEIYEH
IPC: H04L45/28
Filed: 2019-05-31
Abstract: A method for managing network traffic on a portable communication device including a processor, a memory, and a plurality of network interfaces configured to connect to a plurality of networks includes: processing network traffic of an application running on the processor via a first network of the plurality of networks, the first network being specified as a primary network by an operating system running on the processor; monitoring a plurality of network status information associated with the first network; detecting a problem of the first network when one or more parameters of the received network status information is outside of one or more threshold values; in response to detecting the problem in the first network, selecting a second network of the plurality of networks as the primary network; and processing the network traffic via the second network as the updated primary network.
Patent CA-3101924-A1 (CA)
Inventor: NIROGI RAMAKRISHNA
IPC: A61P25/00
Filed: 2018-08-01
Abstract: La présente invention concerne de nouvelles méthodes de traitement de la narcolepsie, de la somnolence diurne excessive, de l'apnée obstructive du sommeil, de troubles du sommeil liés au rythme circadien, des troubles du sommeil et de la vigilance associés à la maladie de Parkinson, de la sclérose en plaques, de la démence ou du trouble du déficit de l'attention avec hyperactivité par l'administration d'une quantité thérapeutiquement efficace d'un agoniste inverse du récepteur de l'histamine-3 (H3R), le N-[4-(1-cyclobutylpipéridin-4-yloxy)phényl]-2-(morpholin-4-yl)acétamide, ou d'un sel pharmaceutiquement acceptable de celui-ci. La présente invention concerne en outre l'utilisation desdits composés dans la fabrication d'un médicament destiné au traitement des troubles décrits ici.
Patent CA-3102772-A1 (CA)
Inventor: Monty stephen
IPC: E04G17/00
Filed: 2020-12-17
Abstract: Il est décrit un appareil et une méthode connexe. Lappareil en question constitue un raccord structurel servant à fixer des composants structurel dans des coffrages isolés. Le raccord structurel se compose dun ensemble de boulon cylindrique à filet double qui saligne sur les ouvertures du mur du coffrage isolé. Une extrémité de lensemble de boulon cylindrique sencastre dans le creux du mur du coffrage isolé et du béton et des barres de renforcement sintroduisent dans les ouvertures de lensemble de boulon cylindrique. Le filetage de lextrémité opposée de lensemble de boulon cylindrique lui permet daccommoder un boulon à tête à embase à filet double. Lensemble de boulon cylindrique sert à monter des lisses, des étriers à solives de plancher et des raccords de ferme au mur du coffrage isolé, de manière à les fixer les uns aux autres pour quils agissent comme une seule structure en ce qui concerne la résistance aux charges de pliage et de sous-pression imposées par de grandes forces comme les systèmes de plancher et de ferme.
Patent CA-3106458-A1 (CA)
Inventor: SPRINGATE CHRISTOPHER MICHAEL KEVIN
IPC: A61P41/00
Filed: 2019-07-24
Abstract: High-molecular-weight fucan compositions comprising a therapeutically effective, medically acceptable fucan in a composition comprising wherein the fucan, for example, has a molecular weight distribution in which more than 60 % w/w of the composition has a molecular weight above 100 kDa.
Patent CA-3106647-A1 (CA)
Inventor: NAPIER ANDREW
IPC: C22B26/12
Filed: 2019-07-24
Abstract: The disclosure relates to processes for extracting lithium from an uncalcined lithium- bearing silicate and recovering a lithium salt therefrom. A slurry of the uncalcined lithium-bearing silicate and a caustic solution is heated in an autoclave to provide a Li- rich sodalite phase. The Li-rich sodalite phase is leached with a dilute acid to produce a lithium-rich pregnant liquor. Various subsequent processes to treat the lithium-rich pregnant liquor to recover a lithium salt, such as lithium phosphate, lithium carbonate, lithium sulphate or lithium hydroxide, are described.
Patent CA-3106920-A1 (CA)
Inventor: GUIDRY KIRK PAUL
IPC: E21B43/26
Filed: 2012-10-10
Abstract: 87832771 ABSTRACT A system, comprising: a land-based horizontal fracturing tree, comprising: a first hydraulic fracturing bore configured to flow a first fluid, wherein the first hydraulic fracturing bore comprises: a horizontal flow path extending along a first horizontal axis; and a vertical flow path extending along a vertical axis of a wellhead, wherein a horizontal flow path length of the horizontal flow path is greater than a vertical flow path length of the vertical flow path, and the first horizontal axis is generally perpendicular to the vertical axis of the wellhead. Date Recue/Date Received 2021-01-22
Patent CA-3112387-A1 (CA)
Inventor: MUNNEKHOFF ANN-KATRIN
IPC: C12Q1/6895
Filed: 2019-09-11
Abstract: A method for establishing, restoring or increasing the Rz2 gene mediated resistance to the Beet necrotic yellow vein virus (BNYVV) in the target plant is enabled via the identification and provision of a gene which modulates said resistance according to the invention. In particular, the BNYVV resistance mediated by the Rz2 resistance gene depends on the presence of the gene of the present invention. The gene being involved in conferring said resistance, and embodiments of the present invention that are described in the preceding, offer additional applications, e.g., the use of the resistance modifying gene allele in cis-genetic or trans-genetic approaches, with the goal of developing new resistant cultivars.
Patent CA-3112797-A1 (CA)
Inventor: VAN ZUTPHEN PIETER PETRUS HENDRIKUS
IPC: G01N33/10
Filed: 2019-09-16
Abstract: The invention relates to a device (2) and a method for a contactless analysis of a food product (2), in particular for the contactless analysis of a dough product. The device (2) comprises a distance sensor (3) configured for measuring a distance (d) between the device (1) and the product (2), and a nozzle (4) configured for directing a jet (5) of pressurized fluid to a position (6) on a surface (7) of said product (2). The distance sensor (3) is arranged for measuring the distance (d) between the device (1) and the position (6) of the surface (7) where the jet (5) of pressurized fluid is directed to.
Patent CA-3113059-A1 (CA)
Title: Synthetic binding agents for limiting permeation through mucus
Inventor: LAI SAMUEL
IPC: A61P31/18
Filed: 2019-09-23
Abstract: Synthetic binding agents for reducing the fraction of targets that can permeate through mucus and/or freely divide, and methods of reducing mucosal permeation and/or free division of a target using these synthetic binding agents.
Patent CA-3113295-A1 (CA)
Inventor: BEYNET YANNICK
IPC: B29C64/00
Filed: 2019-10-01
Abstract: This invention concerns a method for producing a counter-form (20) for manufacturing a part having a complex shape (24) by pressure sintering densification. The counter-form (20) is formed from successive layers produced by numerically-controlled three-dimensional (3D) additive printing according to the following steps: - numerically recording a three-dimensional negative of the part to be produced (24) in a control unit of a three-dimensional additive printing system in order to constitute the positive form of the counter-form to be produced; - producing the counter-form (20) using a 3D additive printing technique. The part having a complex shape (24d) is then manufactured by pressure sintering, then separated from the counter-form which is also sintered (20d).
Patent CA-3113541-A1 (CA)
Inventor: LIAO CHENG
IPC: C12P21/08
Filed: 2019-09-25
Abstract: The present invention provides an anti-ox40 antibody, an antigen-binding fragment thereof, and the pharmaceutical use. Further, the present application provides a chimeric antibody and a humanized antibody, the chimeric antibody and the humanized antibody comprising a CDR region from the anti-OX40 antibody and the antigen-binding fragment thereof, and also provides a pharmaceutical composition comprising the anti-OX40 antibody and the antigen-binding fragment thereof, and the use thereof as a drug for treating cancers.
Patent CA-3113982-A1 (CA)
Inventor: YOSHIMURA TOMOKI
IPC: H04W72/12
Filed: 2019-09-26
Abstract: A terminal device is provided with: a reception unit which monitors, in an active downlink BWP of a serving cell in a secondary cell group (SCG), a PDCCH accompanied by a DCI format used for PDSCH scheduling, and receives the PDSCH in the downlink BWP; and a transmission unit which transmits HARQ-ACK in PUCCH. The value NRIV of a frequency resource allocation field included in the DCI format is equal to Nsize BWP*(LRBs-1)+RBstart when LRBs-1 is not more than floor(Nsize BWP/2). The NRIV is equal to Nsize BWP*(Nsize BWP-LRBs+1)+(Nsize BWP-1-RBstart) when LRBs-1 is greater than floor(Nsize BWP/2). The floor(Nsize BWP/2) is the largest integer in a range not exceeding Nsize BWP/2. The RBstart is a resource block at the head of PDSCH allocation. The LRBs is the number of resource blocks allocated to the PDSCH. The Nsize BWP, when the DCI format is detected in a common search space, is given by the number of resource blocks of an initial downlink BWP set by a first parameter.
Patent CA-3114119-A1 (CA)
Inventor: BARBARIC MLADEN
IPC: A61M15/00
Filed: 2019-10-16
Abstract: In some embodiments, a system includes a cartridge assembly and a pen assembly. The cartridge assembly includes a mouthpiece assembly and a bracket cartridge assembly. The mouthpiece assembly includes a mouthpiece component defining a mouthpiece opening and an outer housing defining a vapor outlet and including a recessed sidewall portion. The pen assembly includes a pen housing and a bracket assembly configured to engage with the bracket cartridge assembly of the cartridge assembly such that a temperature of a coil of a wick assembly of the cartridge assembly may be increased such that a carrier material disposed near the coil may be vaporized by the coil. When the cartridge assembly is engaged with the pen housing, the recessed sidewall portion of the outer housing and an inner surface of the pen housing form a fluid path from the vapor outlet to the mouthpiece opening.
Patent CA-3128089-A1 (CA)
Title: Reduction et elimination d'oxydes de traitement sur de l'acier inoxydable
Inventor: PRICE LEROY R
IPC: B21B45/04
Filed: 2020-02-21
Abstract: Les oxydes formés pendant le recuit de la bande d'acier inoxydable sont éliminés par des brosses abrasives, au lieu d'un décapage à base d'acide ou de sel fondu. Dans certains modes de réalisation, la bande d'acier inoxydable est traitée avec un élément de terre rare ou un métal de transition associé avant recuit, puis brossée après recuit pour éliminer tout oxyde. La sélection de brosses peut conférer un aspect fini à l'acier inoxydable poli de manière classique.
Patent CA-3129167-A1 (CA)
Title: Nonhormonal unisex contraceptives
Inventor: LISHKO POLINA V
IPC: A61P15/18
Filed: 2020-02-21
Abstract: Nonhormonal unisex contraceptive products, compositions, formulations and methods of use comprise an effective amount of a targeted mild mitochondria uncoupler.
Patent CA-3133174-A1 (CA)
Inventor: KELM GARY ROBERT
IPC: C07J7/00
Filed: 2020-03-16
Abstract: The present application relates to a rinse-off composition comprising an oil phase and an aqueous surfactant matrix, wherein one or more active agents are dissolved in one or more non-polar, water-immiscible solvents, and the oil phase is dispersed in the aqueous surfactant matrix. The present application also relates to methods of delivering the active agent(s) to a subject in need thereof topically, for example to the skin, the hair, and scalp. The present application also relates to use of the rinse-off compositions to treat and/or prevent topical conditions such as dermatitis and psoriasis. In some embodiments, the rinse-off compositions of the present application are shampoo compositions.
Patent CA-3133310-A1 (CA)
Title: Ofdm and ofdma profile assignments for cable modems
Inventor: HANKS WILLIAM TURNER
IPC: H04L5/00
Filed: 2020-06-15
Abstract: Systems and methods for dynamically updating bit loading profile assignments among a plurality of cable modems.
Patent CA-3133423-A1 (CA)
Title: Systeme de recuperation acceleree d'un bloc nerveux a courant direct (dc) en utilisant la repolarisation
Inventor: VRABEC TINA L
IPC: A61N1/05
Filed: 2020-03-13
Abstract: La présente invention concerne la récupération accélérée d'un bloc nerveux à courant direct (DC) pouvant être atteint en utilisant la repolarisation. Une forme d'onde à courant direct (DC) peut être appliquée à un nerf sur une durée suffisante pour atteindre le bloc nerveux. La forme d'onde DC peut être commutée vers une autre forme d'onde DC de polarité inversée, qui peut être appliquée pour une seconde fois, amenant le nerf à entrer dans un cycle de repolarisation afin d'accélérer le temps de récupération pour le nerf. En outre, l'application simplement d'une forme d'onde DC de sous-seuil au nerf sur une durée en lui-même peut améliorer une réponse du nerf sans bloquer la conduction dans le nerf.
Patent CA-3135660-A1 (CA)
Title: Fabrication continue de prepolymeres polyurethane
Inventor: BODMANN DANIELA
IPC: C08G18/66
Filed: 2020-03-29
Abstract: La présente invention concerne un procédé continu de fabrication de prépolymères polyuréthane dans un réacteur à temps de séjour ayant un écoulement bouchonnant, ainsi que l'utilisation desdits prépolymères polyuréthane pour la fabrication de polyuréthanes.
Patent CA-3135752-A1 (CA)
Inventor: ALAHAKOON USHAN
IPC: C12N5/04
Filed: 2021-10-25
Abstract: Il est décrit une variété de canola désignée 19GS23181 et la semence, les plantes et parties de plantes produites à partir dun testeur commun. Les méthodes pour produire une variété de canola comprennent le croisement de la variété de canola 19G523181with avec une autre plante de canola. Des méthodes sont décrites pour produire une plante de canola qui renferme dans son matériel génétique au moins un des traits introgressés dans la 19G523181through par conversion rétrocroisée et/ou transformation rétrocroisée, et les semences, plantes et parties de plantes du canola produites de ce fait. Il est décrit la variété de canola 19G523181, les semences, les plantes produites à partir des semences, les parties de plantes et les variantes, mutations et légères modifications de la variété de canola 19G523181.
Patent CA-3136817-A1 (CA)
Title: Birth tissue-derived products and preparation and uses thereof
Inventor: QIN XIAOFEI
IPC: A61K35/48
Filed: 2020-04-16
Abstract: The present invention provides a composition for treating a pathological condition in a body part of a patient in needed thereof, comprising an effective amount of a birth tissue elute or birth tissue particulates. A method for preparing the birth tissue elute, for example, an umbilical cord elute, is also provided. A method for treating a pathological condition in a body part of a patient in needed thereof is further provided.
Patent CA-3137003-A1 (CA)
Title: Cytidine derivatives and methods of forming cytidine derivatives
Inventor: TZAKOS ANDREAS
IPC: C07H19/06
Filed: 2020-04-14
Abstract: Disclosed herein are nucleoside derivatives, cytidine derivatives and Gemcitabine derivatives and methods of forming nucleoside derivatives, cytidine derivatives and Gemcitabine derivatives.
Patent CA-3140033-A1 (CA)
Title: Medication management among a network of medical entities
Inventor: ZECH NEAL
IPC: G16H40/20
Filed: 2020-05-13
Abstract: Features relating to a medication management module for use in a network of medical entities are provided. Aspects of the current subject matter provide for tracking or otherwise managing medication inventory at the medical entities of the network. Additional aspects relate to sharing medication inventory information among entities of the network to, for example, enable borrowing of medication among entities. Other aspects relate to predicting availability of medication at the entities of the network. The medication management module provides visibility of medication inventory throughout the network of the medical entities to facilitate and/or cause sharing of medication.
Patent CA-3140082-A1 (CA)
Title: Combined mixed-cell and raceway aquaculture device, system and method of use thereof, and method for growing fish thereby
Inventor: HOLDER JOHN PEARSON
IPC: C02F9/14
Filed: 2020-05-13
Abstract: An energy efficient aquaculture system combining mixed-cell and raceway configurations. The system comprises a raceway tank, a raceway channel, and a first and a second water purification subsystems. The raceway tank includes an elongated tank body divided into a plurality of virtual cells having a generally circular cross-sectionally shaped hydraulic pattern. Purified water enters the tank via a first weir at a first end, flows across the tank toward an opposite second end, and exits via a second weir at the second end. A portion of water is removed via center bottom drains in each of the cells. The system may include one or more of a hatching subsystem, a nursey subsystem, a feeding subsystem, a finishing subsystem, and a fishing pumping system for transfer of fish between raceway tanks. A method of growing fish for commercial production using the aquaculture system is also provided.