baber/WOPTO huggingface dataset:
Patent DK-0403333-T3 (DK)
Inventor: MONTAGNIER LUC
IPC: C07K16/00
Filed: 1990-06-05
Granted: 2000-03-20
Abstract: Oligonucleotide (I), comprising a specific sequence (A) of the gene gag or gene pol, and susceptible to hybridize at 60[deg]C+-1[deg]C with the genomes of viruses HIV-1 Bru, HIV-1 Mal, HIV-1 Eli, HIV-2 Rod or SIV Mac; or a sequence complementary to a sequence (A), is new. Independent claims are also included for: (1) couple of oligonucleotide primers (II), for carrying out a gene amplification of the gene gag or gene pol of the virus of the type HIV-1 Bru, HIV-1 Mal, HIV-1 Eli, HIV-2 Rod or SIV Ma, where the primers consists each one of: a specific sequence of the gene gag or gene pol, and susceptible to hybridize at 60[deg]C+-1[deg]C with the genomes of viruses HIV-1 Bru, HIV-1 Mal, HIV-1 Eli, HIV-2 Rod or SIV Mac; or a sequence complementary to the sequence (A); (2) a process of gene amplification of nucleic sequences of the gene gag or the gene pol of virus of type (HIV-1 and/or HIV-2, and/or SIV, from a biological sample, comprising: (a) a stage of extraction of the nucleic acid to be detected belonging to the genome of the virus of the HIV-1 type, HIV-2 or SIV, optionally present in the biological sample, and optionally a stage of treatment using a reverse transcriptase of the nucleic acid if the latter is in the form of RNA; (b) a cycle comprising: denaturation of the double stranded nucleic acid to be detected, which leads to the formation of a single strand nucleic acid, hybridization of each strand of nucleic acid, obtained at the stage of denaturation, with at least a primer or a couple of primers of (II), by setting in contact the strands with at least a couple of the primers, formation from primers, of complementary DNA strands on which they are hybridized in the presence of a DNA polymerase and four different nucleosides triphosphate (NTP), which leads to the formation of a greater number of double strand nucleic acid to be detected at the stage of preceding denaturation, and repetition of the cycle for a determined number of times to obtain the nucleic sequence to be detected optionally present in the biological sample in a proportion sufficient to allow its detection; and (c) a stage of detection of the optional presence of the nucleic acid belonging to the genome of the virus in the biological sample; and (3) a kit for carrying out the process of gene amplification of nucleic sequences of the gene gag or the gene pol of virus of type (HIV-1 and/or HIV-2, and/or SIV, from a biological sample, comprising: at least a primer or a couple of oligonucleotidic primers of (II); reagents appropriate to be used in cycle of amplification, in particular DNA polymerase, four different nucleotide triphosphate, and buffer 10X; and one (or several) probe, can be marked, capable of hybridizing with the amplified sequence of nucleic acid to be detected.
Patent DK-0460334-T3 (DK)
Inventor: BONAN SOLE JESUS
IPC: A45D26/00
Filed: 1991-01-22
Granted: 1995-07-17
Abstract: The applicator has a frame (1) with two metallic plates (2) fixed inside it. The plates are joined to electric heating elements (7) and transmit the heat to a reservoir (5) which contains the wax. The reservoir has a head at the front which holds a roller (6). One side of each plate is bent at a right angle to form a rectangular body. A tongue (10), cut out in each plate, extends inwards and forms an intermediate partition. The reservoir has a longitudinal notch (11), opening backwards, into which the partition fits.
Patent DK-0462812-T3 (DK)
Inventor: BIRD THOMAS GEOFFREY COLERICK
IPC: C07D409/14
Filed: 1991-06-19
Granted: 1996-04-22
Abstract: The invention concerns a heterocyclene derivative of the formula I, or a pharmaceutically-acceptable salt thereof. The invention also concerns processes for the manufacture of a heterocyclene derivative of the formula I, or a pharmaceutically-acceptable salt thereof, and pharmaceutical compositions containing said compound. Also included in the invention is a method of treating various inflammatory or allergic diseases using a heterocyclene derivative of the formula I, or a pharmaceutically-acceptable salt thereof, and the use of such a compound in the production of a new medicament for such use.
Patent DK-0455553-T3 (DK)
Inventor: BASIN GERARD
IPC: E01C7/26
Filed: 1991-04-30
Granted: 1995-06-26
Abstract: Bituminous mix filled with a mineral wool and process for its preparation. 
<??>The mineral wool is characterised by its micron size; it is treated with a finish based on fatty acid amine oxide. 
<??>The process provides for the preparation of nodules from the mineral wool mat. 
<??>Application to terracings and road dressings and in particular with draining mixes. 
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Patent DK-0510487-T3 (DK)
Inventor: SUGAWARA TOHRU
IPC: C07C231/02
Filed: 1992-04-14
Granted: 1996-03-11
Abstract: An automatic synthesizing apparatus (I,II) for continuously effecting automatically by a controlling apparatus (II) all the operations including the supplying of samples into reaction vessel and so on, reaction processing of the contents within the reaction vessels (12), PH adjustment (13), extraction/dehydration processing (14), purification (16) of the contents, further analysis (15) of the reaction condition so as to produce the target compounds. Many basic unit operation procedures are made, stored so that programs for effecting the operation controlling of the automatic synthesizing apparatus may be extremely easily made. The innumerable syntheses programs in the chemical experiments may be effected simply by the inputting of the operation names of the unit operation procedures in the operational orders when the synthesis order programs may be made for each target compound. <IMAGE>
Patent DK-0529235-T3 (DK)
Inventor: HUBBARD DIGBY J
IPC: B67D1/04
Filed: 1992-06-30
Granted: 1995-03-13
Abstract: This invention relates to a keg tap for dispensing a pressurised liquid from a container which is provided with a keg seal and in the lower end of which an insert (2) is arranged, which is penetrated by a valve opening rod (3) and in which bores are arranged on holding elements, into which project prongs (6)of a fastenable lever (10) which is provided with a fork (9), an upper and a lower flange (11, 11') being moulded onto the valve opening rod (3) near the bores of the insert (2), between which flanges (11, 11') engage the prongs of the fork, which are also situated opposite one another, and the valve opening rod (3) being movable in a reciprocating fashion with the aid of the lever (10) and a sleeve (13), which partially grips round the lower end of the casing, being pushed onto the latter and fixed, casing (1), insert (2) and sleeve (13) having slots situated laterally next to the valve opening rod (3), in which slots the fork (9) of the lever (10) is guided, and holding elements (14) being moulded onto the sleeve (13) to fasten the tap on the keg. 
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Patent DK-0495563-T3 (DK)
Inventor: SPIEGEL EHUD
IPC: H04N1/60
Filed: 1992-01-02
Granted: 2000-11-27
Abstract: An integrated computerized system for use in printing including apparatus for providing at least one digital representation of at least one page, digital storage apparatus for storing the at least one digital representation of the at least one page, imposition apparatus for receiving at least one digital representation of at least one page and arranging the at least one digital representation of the at least one pages in accordance with a desired plate layout, thereby to define a plate image, and press set-up apparatus for extracting from the at least one digital representation of at least one page and providing to a printing press, press set-up data. <IMAGE>
Patent DK-0505232-T3 (DK)
Inventor: ZALKIN DANIEL
IPC: A61M16/00
Filed: 1992-03-09
Granted: 1995-12-04
Abstract: The device for controlling the overpressure generating turbine (3) comprises means (15, 17, 18, 20, 22) for detecting periodic variations in the regime of the turbine and means (I, E) for fixing two reference levels of the pressure delivered in order to modulate the overpressure provided by the turbine as a function of the respiratory parameters of the user which are detected in situ by a pressure sensor (8). Application in particular to respiratory aid for individuals suffering from respiratory disorders when sleeping. <IMAGE>
Patent DK-0594950-T3 (DK)
Inventor: PARADISO PETER R
IPC: A61P31/04
Filed: 1993-07-22
Granted: 1999-09-13
Abstract: A combined pediatric vaccine composition featuring, in a single immunizing dose, a mixture of diphtheria, tetanus and pertussis antigens and a conjugate of fragments of the capsular polysaccharide antigen of Haemophilus influenzae type b and CRM197 protein in a pharmaceutically acceptable aqueous vehicle is provided. The combined vaccine composition exhibits an enhanced antibody response by infants to each of the four vaccine components.
Patent DK-0553016-T3 (DK)
Inventor: LESIEUR DANIEL
IPC: A61P9/00
Filed: 1993-01-19
Granted: 1997-12-01
Abstract: The invention relates to the compounds of general formula (I): <IMAGE>  in which:  R3 represents a <IMAGE> group, R1, R2, R6 and R7 being as defined in the description.   Medicaments.
Patent DK-0601954-T3 (DK)
Inventor: VEGA MORILLO RAUL
IPC: G07F9/00
Filed: 1993-12-02
Granted: 2000-12-18
Abstract: Coin-operated machine for dispensing foodstuffs preserved in frozen condition and ready to be served hot in situ consisting of a casing (2) having a door (3) inside which there is a freezing unit (4) having doors and supporting elements, connected to a compressor unit (6) and a motor (30). The freezing unit (4) has, inside, trays (7) on supporting guides (8) fitted with a multiplurality of hooks (9) acting as electric resistances. On the lower side, there is a hopper (20) connected with the upper entrance of an oven (21) having an upper door (22) and a front door (23), The freezing unit contains the frozen product in a plastic package which has a ring or strip of low density arranged on the hooks (9), the assembly operating from a computer (13) acting on all the mechanisms. <IMAGE>
Patent DK-0662631-T3 (DK)
Inventor: MANICO JOSEPH ANTHONY
IPC: G03C3/00
Filed: 1994-12-17
Granted: 2000-01-17
Abstract: A flexible film holder (10) having a format which is consistent with a first filmstrip size. The film holder (10) comprises a first sheet member (14) and second sheet member (16) which are secured to each other so as to form a longitudinally extended pocket (22) therebetween for receiving and holding a filmstrip having a size smaller than the first filmstrip size. <IMAGE>
Patent DK-0708806-T3 (DK)
Inventor: SHANKLAND IAN ROBERT
IPC: C07C19/08
Filed: 1994-05-27
Granted: 1997-10-27
Abstract: Azeotrope-like compositions comprising trifluoromethane and carbon dioxide or trifluromethane, hexafluoroethane and carbon dioxide are stable and have utility as refrigerants for heating and cooling as well as fire extinguishing compositions.
Patent DK-0733214-T3 (DK)
Inventor: AVERBACK PAUL
IPC: C12P21/00
Filed: 1994-12-19
Granted: 1999-03-15
Abstract: DMS present in the brain of individuals susceptible to cerebral amyloidosis disintegrate into DMS components to form cerebral amyloid plaques and other DMS components that are removed from the brain via circulating bodily fluids. Detecting the presence of these removed DMS components and/or antibodies thereto in circulating bodily fluids provides a diagnostic mechanism to determine the onset of cerebral amyloid plaque formation. Detecting the presence of these removed DMS components and/or antibodies thereto in circulating bodily fluids also provides a diagnostic mechanism to determine the efficacy of treatment regimes for preventing cerebral amyloid plaque formation. Antibodies also can be raised against isolated DMS components and subsequently utilized in a diagnostic method capable of detecting the onset of cerebral amyloid plaque formation.
Patent DK-0741944-T3 (DK)
Inventor: EGENDORF ANDREW
IPC: H04N7/16
Filed: 1995-01-17
Granted: 2001-09-17
Abstract: A television cable billing method comprises establishing a continuous communications link between a provider and a plurality of customers over a single duplex transmission line. A billable account number is assigned to each customer and each customer is billed a flat fee rate for the continuous communications link. A customer communicates a request for a product or service over the communications link together with the customer's billing account number. The product or service is provided to the customer over the communications link by the provider and the customer's billing account number is billed for the provided product or service. The communications link is maintained both before and after the product or service is provided.
Patent DK-0704049-T3 (DK)
Inventor: WILL JUERGEN
IPC: G01F23/74
Filed: 1995-03-31
Granted: 1998-09-28
Abstract: A float-controlled level switch with continuously adjustable switching points allows the level of liquids to be continuously regulated in selected height ranges. This is also the task of state-of-the-art vertical arrangements of several complete float type switches secured to a bar or of float type switches that may be adjusted only in a grid. Their disadvantages, such as their high complexity or the linking of the switching points to a grid, are eliminated by the invention. For that purpose, a holding element (section bar 11) provided with guiding tracks is located in the sliding tube (7) of the level switch, and the specifically designed switch element carriers (12) may be continuously moved in the guiding tracks. The switch element carriers (12) may be adjusted by means of outer adjusting elements (adjusting spindles 19), or by manually removing the section bar (11) from the level switch. Electric current is supplied to the switch elements (Reed switches 17) through bus bars (15) embedded in the guiding tracks and by contact elements (contact springs 16) that slide on the bus bars. The advantage of this solution is that it allows the switching points to be freely selected.
Patent DK-0756596-T3 (DK)
Inventor: MOLDT PETER
IPC: C07D451/02
Filed: 1995-04-12
Granted: 2002-12-23
Abstract: PCT No. PCT/EP95/01358 Sec. 371 Date Oct. 11, 1996 Sec. 102(e) Date Oct. 11, 1996 PCT Filed Apr. 12, 1995 PCT Pub. No. WO95/28401 PCT Pub. Date Oct. 26, 1995The present invention discloses compounds of the formula,   <IMAGE>    <IMAGE>   any mixture thereof, or a pharmaceutically acceptable salt thereof; wherein R, R3, and R4 each have the meanings set forth in the specification. The compounds possess valuable pharmaceutical properties as monoamine neurotransmitter, i.e dopamine, serotonin, noradrenalin, reuptake inhibitors.
Patent DK-0710304-T3 (DK)
Inventor: CONTI PAOLO
IPC: D04B9/56
Filed: 1995-05-12
Granted: 1999-06-23
Abstract: PCT No. PCT/IT95/00072 Sec. 371 Date Jan. 16, 1996 Sec. 102(e) Date Jan. 16, 1996 PCT Filed May 12, 1995 PCT Pub. No. WO95/31595 PCT Pub. Date Nov. 23, 1995A push rod (38) with a pick-up hook (38A) at the end is moved in an axial plane of symmetry to engage by means of the pick-up hook in an intermediate position the partial initial courses (M1) of a pocket (M2) and to bring them progressively to the side opposite the arc of working needles with the progressive formation of the fabric; a body in the form of a shaped annular ring (18), disposed inside the needle cylinder, has a radial slot (22) for said push rod (38) and radial slots (24) in the area opposite said arc of working needles; hooks (60) movable in said slots (24) can be moved from a concealed position to a raised position to make pin-shaped appendages (62) penetrate into the fabric along the initial edge (M1) when this has been brought by the push rod (28) to the side opposite that of the arc of working needles, and subsequently to move the initial comes (M1) progressively up to the needles which are raised and inserted into the fabric to engage said edge (M1).
Patent DK-0727423-T3 (DK)
Inventor: CHOI JONG KWON
IPC: C07B61/00
Filed: 1994-03-04
Granted: 2001-09-24
Abstract: The present invention relates to a process for preparing the sulfonylchloride compound of formula (V) and the compound of formula (VIII), both of which are useful as an intermediate compound for preparing the sulfonylurea derivative of formula (I) and to a novel intermediate compound of formula (VIII): wherein R<sup>1</sup> represents hydrogen, C<sub>1</sub>-C<sub>4</sub> alkyl or phenyl, R<sup>2</sup> represents hydrogen, C<sub>1</sub>-C<sub>4</sub> alkyl, allyl or propargyl an R<sup>3</sup> represents hydrogen, methyl, ethyl or phenyl.
Patent DK-0757248-T3 (DK)
Inventor: SILVA RENUKA DE
IPC: C07D321/00
Filed: 1996-07-31
Granted: 2001-08-27
Abstract: Improved assay methods utilizing stable, enzymatically triggered chemiluminescent 1,2-dioxetanes with improved water solubility are provided. Assays are performed by a capsule chemistry analytical assay method wherein fluid capsules comprising discrete aqueous segments containing either a chemiluminescent dioxetane reagent or an activating agent separated by an oil-based isolating fluid are flowed through a conduit, and subsequently reacted to produce light. The improvement comprises using a dioxetane substituted with two or more water-solubilizing groups disposed on the dioxetane structure to provide the chemiluminescence. Compositions comprising such a dioxetane, a non-polymeric surfactant enhancer and optionally a fluorescer, provide enhanced chemiluminescence and eliminate the problem of reagent carryover when used in assays performed on capsule chemistry analytical systems. <IMAGE>
Patent DK-0800800-T3 (DK)
IPC: A61F2/06
Filed: 1996-08-29
Granted: 1999-04-19
Abstract: The stent comprises a tubular body movable from the compresses state into the expanded one of larger diameter. A large number of apertures (13,14) in the wall of the body allow its expansion. Both in the compressed and the expanded state the apertures extend in the lengthwise directions. The reinforced connecting portions (15) are situated between adjacent apertures in the lengthwise direction. The sections of wall material between the apertures can form enclosing edges for the latter, joined together in the lengthwise direction and elastic to allow stent expansion. In the peripheral direction they can be joined together by the connecting portions.
Patent DK-0810951-T3 (DK)
Inventor: THOMPSON NIGEL
IPC: B65D41/04
Filed: 1996-02-14
Granted: 1999-11-01
Abstract: The invention provides a container closure moulded in one piece from a plastics material and comprising a crown (11), a dependent skirt (12), the radially inner surface of which is formed with a screw thread (13), a surface (16) which is flared in a direction away from the top being formed on the internal surface of the skirt where it joins the crown and an annular resilient fin (18) extending downwardly and outwardly from an articulation position (26) on the underside of the top at position spaced radially inward of said flared surface having a length such as to permit at least its portion adjoining its free edge to lie against the flared surface (16), wherein the fin is deformed outwardly by the top of the neck of the container to which the closure is to be applied, characterised by a continuous or discontinuous locator annulus (30) depending downwardly from the undersurface of the crown (11) and disposed radially inwardly of the fin (18), the locator annulus extending downwardly by a distance greater than the fin (18) and having an outer diameter just smaller than that of the inner diameter of the container neck (20) with which it is to be used. Closures of this type allow effective reliable capping.
Patent DK-0824350-T3 (DK)
Inventor: MEINGASSNER JOSEF GOTTFRIED
IPC: A61K31/495
Filed: 1996-05-10
Granted: 2003-11-03
Abstract: PCT No. PCT/EP96/02022 Sec. 371 Date Nov. 12, 1997 Sec. 102(e) Date Nov. 12, 1997 PCT Filed May 10, 1996 PCT Pub. No. WO96/35423 PCT Pub. Date Nov. 14, 1996Use of a combination of the squalene epoxidase inhibitor terbinafine and an azole 14-alpha-methyldemethylase inhibitor (fluconazole or itraconazole) in mycotic infections caused by azole-resistant fungal strains, and corresponding pharmaceutical compositions, process and method.
Patent DK-0835262-T3 (DK)
Inventor: VICKERY BRIAN H
IPC: C12N1/21
Filed: 1996-06-03
Granted: 2003-07-07
Abstract: Synthetic polypeptide analogs of parathyroid hormone PTH, parathyroid hormone related peptide PTHrp, and of the physiologically active truncated homologs and analogs of PTH and PTHrp, in which amino acid residues (22-31) form an amphipathic  alpha -helix, said residues (22-31) selected from hydrophilic amino acids (Haa) and lipophilic amino acids (Laa) ordered in the sequence:Haa(Laa Laa Haa Haa)2 Laaand their pharmaceutically acceptable salts are useful for the prophylaxis and treatment of corticosteroid induced osteopenia in mammals.
Patent DK-0873303-T3 (DK)
Inventor: TRUMBO DAVID L
IPC: C08F212/14
Filed: 1996-08-12
Granted: 2000-09-25
Abstract: A novel ethylenically-unsaturated 1,3-diketoamide functional compound, polymers comprised thereof, and latex formulations containing polymeric ingredients having 1,3-diketoamide functional pendant moieties are disclosed. The 1,3-diketoamide functional pendant moieties have excellent hydrolytic stability.
Patent DK-0848608-T3 (DK)
Inventor: FARINAS KATHLEEN C
IPC: A61K9/70
Filed: 1996-09-06
Granted: 2001-02-19
Abstract: Methods are provided for manufacturing transdermal drug delivery systems containing supersaturated drug reservoirs, such that higher drug fluxes are obtained. The methods involve heating the drug reservoir components to a predetermined temperature. Generally, this temperature is higher than the depressed melting temperature of the polymer-drug admixture which will serve as the drug reservoir. In an alternative embodiment, wherein heat treatment of the reservoir components results in a system having two liquid phases, the predetermined temperature is calculated so as to be higher than the melting temperature of the pure drug. Drug reservoirs and novel transdermal delivery systems prepared using the disclosed techniques are provided as well.
Patent DK-0796622-T3 (DK)
Inventor: HODGEN GARY D
IPC: A61K38/09
Filed: 1997-03-18
Granted: 2004-01-12
Abstract: A growth such as a tumor, hypertrophied tissue or cyst is biopsied or more completely excised subsequent to the administration of an effective amount of a gonadotropin releasing hormone analog or other inhibitor of ovarian steroid production or action.
Patent DK-0906338-T3 (DK)
Inventor: DRUCKER DANIEL J
IPC: A61K38/00
Filed: 1997-04-11
Granted: 2003-03-03
Abstract: Analogs of glucagon-like peptide-2, a product of glucagon gene expression, have been identified as intestinal tissue growth factors. Their preparation by synthesis is described.
Patent DK-0963780-T3 (DK)
Inventor: WILD WERNER
IPC: B01D53/85
Filed: 1998-06-08
Granted: 2006-07-10
Abstract: In the process, the bacterial conversion (reduction) of carbon dioxide takes place within underground porous or fine crevice structure (13,14), directly above a closed thick structure. The removal of carbon dioxide from exhaust gas in combustion engines, involves bacterially converting carbon dioxide to methane and depositing and storing both gases in the outer atmosphere.
Patent DK-0973794-T3 (DK)
Inventor: TESSIER-LAVIGNE MARC
IPC: A61K31/7088
Filed: 1998-02-19
Granted: 2002-11-11
Abstract: The invention provides methods and compositions relating to vertebrate UNC-5 proteins which function as receptor proteins for netrins, a family of cell guidance proteins. The proteins may be produced recombinantly from transformed host cells from the disclosed vertebrate UNC-5 encoding nucleic acid or purified from human cells. The invention provides specific hybridization probes and primers capable of specifically hybridizing with the disclosed vertebrate unc-5 gene, vertebrate UNC-5-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.