Patent SG-11201406767V-A (SG)
Title: Microfilter and apparatus for separating a biological entity from a sample volume
Inventor: ARYA SUNIL KUMAR
IPC: G01N33/00
Filed: 2013-04-19
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 24 October 2013 (24.10.2013) WIPOIPCT (10) International Publication Number WO 2013/158045 A1 (51) International Patent Classification: B01D 25/00 (2006.01) G01N27/30 (2006.01) B01D 29/50 (2006.01) A61M1/34 (2006.01) G01N33/00 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/SG2013/000157 19 April 2013 (19.04.2013) English (30) Priority Data: 201202941-9 20 April 2012 (20.04.2012) English SG (71) Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH [SG/SG]; 1 Fusionopolis Way #20-10, Connexis, Singapore 138632 (SG). (72) Inventors: ARYA, Sunil Kumar; c/o Industry Develop­ ment, Institute of Microelectronics, 11 Science Park Road, Singapore Science Park 2, Singapore 117685 (SG). RAH­ MAN, Abdur Rub Abdur; c/o Industry Development, In­ stitute of Microelectronics, 11 Science Park Road, Singa­ pore Science Park 2, Singapore 117685 (SG). JEGATHA, Chandran; c/o Industry Development, Institute of Micro­ electronics, 11 Science Park Road, Singapore Science Park 2, Singapore 117685 (SG). WONG, Chee Chung; c/o In­ dustry Development, Institute of Microelectronics, 11 Sci­ ence Park Road, Singapore Science Park 2, Singapore 117685 (SG). (74) Agent: VIERING, JENTSCHURA & PARTNER LLP; P.O. Box 1088, Rochor Road, Rochor Post Office, Singa­ pore 911833 (SG). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (54) Title: MICROFILTER AND APPARATUS FOR SEPARATING A BIOLOGICAL ENTITY FROM A SAMPLE VOLUME dl 308/309 3 ! 2 306 308/309 306 o 00 T-H cn i-H o CJ o & 314 308/309 308/309 308/309 308/309 (57) Abstract: According to embodiments of the present invention, a microfilter provided. The microfilter includes is a first porous layer and second porous a layer arranged one over the other, wherein the first porous layer includes plurality of a first pores defined through the first porous layer, wherein the second porous layer includes a plurality of second pores defined through the second por - ous layer, and wherein one or more respective second pores are arranged to at least substantially overlap with each respective first pore such that respective a opening defined between perimeter a of the each respective first pore and a perimeter of each of the one or more respective second pores is smaller than a diameter of each first pore. According to further embodiments of the present inven - tion, an apparatus for separating a biological entity from sample volume a is also provided.