baber/WOPTO huggingface dataset:
Patent DE-69628333-T2 (DE)
Inventor: VERNIER MICHEL
IPC: A61P25/00
Filed: 1996-11-14
Granted: 2004-04-08
Abstract: In accordance with the present invention, a novel class of substituted aryl compounds (containing ether, ester, amide, ketone or thioether substitution) that promote the release of ligands involved in neurotransmission have been discovered. In a particular aspect, compounds of the present invention are capable of modulating acetylcholine receptors. The compounds of the present invention are capable of displacing one or more acetylcholine receptor ligands, e.g., <3>H-nicotine, from mammalian neuronal membrane binding sites. Invention compounds may act as agonists, partial agonists, antagonists or allosteric modulators of acetylcholine receptors. Therapeutic indications for compounds with activity at acetylcholine receptors include diseases of the central nervous system such as Alzheimer's disease and other diseases involving memory loss and/or dementia (including AIDS dementia); cognitive dysfunction (including disorders of attention, focus and concentration), disorders of extrapyramidal motor function such as Parkinson's disease, progressive supramuscular palsy, Huntington's disease, Gilles de la Tourette syndrome and tardive dyskinesia; mood and emotional disorders such as depression, anxiety and psychosis; substance abuse including withdrawal symptoms and substitution therapy; neurocrine disorders and dysregulation of food intake, including bulimia and anorexia; disorders or nociception and control of pain; autonomic disorders including dysfunction of gastrointestinal motility and function such as inflammatory bowel disease, irritable bowel syndrome, diarrhea, constipation, gastric acid secretion and ulcers; pheochromocytoma, cardiovascular dysfunction including hypertension and cardiac arrhythmias, as well as co-medication uses in surgical applications.
Patent DE-69629001-T2 (DE)
Inventor: LEBRETON EDWARD T
IPC: F17C1/06
Filed: 1996-08-01
Granted: 2004-06-03
Abstract: A filament-wound pressure vessel is disclosed which has a reinforced access opening. The pressure vessel (10) comprises a blow-molded one piece liner (22) having an outer surface defined by a cylindrical sidewall (26) and oblate ellipsoidal ends (28). The liner defines at least one access opening (24) into the vessel and the access opening has a cylindrical neck portion (30) and a liner flange (32) extending radially outwardly from an open distal end of the neck portion. A cylindrical reinforcement member (12) surrounds the cylindrical neck portion and has a supporting flange (34) at one end thereof, which engages and annular face of the liner flange (32). The reinforcement member (12) has a radially extending supporting foot (38) at the other end thereof, which contacts the outer surface of the liner. The reinforcement member comprises a plurality of separable arcuate segments (40,42) so that it may be assembled around the cylindrical neck portion of the liner. A resin-impregnated filament-winding (18) covers the liner and the supporting foot of the reinforcement member.
Patent DE-69634201-T2 (DE)
Inventor: FENNER RALPH L
IPC: G01N19/10
Filed: 1996-06-03
Granted: 2006-01-05
Abstract: A vapor pressure sensor comprising a substrate having a body with first and second planar parallel surfaces. A hole is formed in the body and extends through and between the first and second surfaces. A beam is disposed in the hole in the body and is formed integral with the body and forms a junction with body and is formed as a cantilever in the hole in the body. The beam has a surface. A vapor adsorbing coating is carried by the surface of the beam and the coating is substantially uniform in thickness. It is adhered to the surface of the beam and is fully shear restrained by the beam. A strain measuring device is carried by the substrate and disposed at the junction between the body and the beam to measure shear forces placed in the beam by the vapor adsorbing coating. The vapor adsorbing coating expands and contracts in directions parallel to the surface of the beam as the vapor adsorbing coating adsorbs and desorbs vapor.
Patent DE-69634407-T2 (DE)
Inventor: BILLETER MARTIN
IPC: A01N65/00
Filed: 1996-08-09
Granted: 2005-12-29
Abstract: The present invention relates, in general, to a methodology for the generation of nonsegmented negative-strand RNA viruses (Pringle, 1991) from cloned deoxyribonucleic acid (cDNA). Such rescued viruses are suitable for use as vaccines, or alternatively, as plasmids in somatic gene therapy applications. The invention also relates to cDNA molecules suitable as tools in this methodology and to helper cell lines allowing the direct rescue of such viruses. Measles virus (MV) is used as a model for other representatives of the Mononegavirales, in particular the family Paramyxoviridae. <IMAGE>
Patent DE-69704914-T2 (DE)
Inventor: HATTON PHILIPPE
IPC: F26B21/02
Filed: 1997-09-04
Granted: 2001-11-22
Abstract: The ventilator is mounted at the upper end of a casing to drive an air flow parallel to the axis of the casing. The outlet opening (33) for the air flow is disposed obliquely with respect to the axis of the casing. The outlet opening can have multiple blades (34) fixed to a plate (36) situated in a plane parallel to that containing the outlet opening so that the flow of air is deflected in a horizontal direction perpendicular to the rows of stacks of product to be dried.   The axis of the casing can form an angle 'a' of between twenty and forty degrees with the plane containing the outlet opening.
Patent DE-69715837-T2 (DE)
Inventor: ARAS JOHN
IPC: G09G3/20
Filed: 1997-04-21
Granted: 2003-01-23
Abstract: A time interleaved bit addressed weighted pulse width modulation (PWM) method and apparatus reduces the bandwidth requirement necessary for providing a plurality of data entries regarding multiple points of information. As is well known, a weighted PWM scheme modulates an output by utilizing a frame time that is divided into events of varying durations; most conventional schemes have each bit in the frame being half the duration of its predecessor. The modulated signal is activated during all, some or none of the events in the frame to develop a signal representing a particular parameter. This method and apparatus can be used in a display for selecting among varying levels of gray scale or from among multiple colors on a palette. In one application for a display, a register containing the same number of data pits as pixels in a row of the display is provided. The register is loaded with one bit per frame for each pixel in the entire row. The bandwidth is reduced because the bit for each of the pixels are not all for the same weight event. This allows a bit for a long duration event to be displayed in one pixel, while more than one bit for shorter duration events to be displayed in another pixel. This obviates the need to load one bit for each pixel in the row during the shortest event duration. The organization of the sequence of the events amongst the various rows can be pseudo-random to achieve reduced bandwidth. If the organization is pseudo-random the order can be pre-selected for an optimized bandwidth or organized into a predetermined format to achieve a pseudo-random effect.
Patent DE-69724058-T2 (DE)
Inventor: PICKERING ANDREW JAMES
IPC: H03K3/0231
Filed: 1997-09-10
Granted: 2004-11-25
Abstract: A ring oscillator comprises a ring of delay stages in which the output of each stage is input to the next stage in the ring. Tuning of the oscillation frequency of the oscillator is achieved by additionally taking outputs from delay stages elsewhere in the ring as one or two secondary inputs to each delay stage and mixing this or these in variable proportions with the primary input. <IMAGE>
Patent DE-69726315-T2 (DE)
Inventor: LOEFFLER GERMAN
IPC: A61M36/04
Filed: 1997-07-04
Granted: 2004-09-09
Abstract: A catheter provided with an elongated tube having channels for the guiding of a radioactive element and for the passage of a guide wire for the catheter as well as fluid under pressure, in which the elongated tube is provided near its distal end on its outer circumference with a recanalization balloon and activatable centering means arranged therein. A by-pass can also be arranged through the recanalization balloon.
Patent DE-69732498-T2 (DE)
Inventor: FRUEH KLAUS
IPC: A61P37/02
Filed: 1997-07-31
Granted: 2006-04-27
Abstract: The human cytomegalovirus (HCMV) genomic US region encodes a family of homologous genes essential for the inhibition of major histocompatiblity complex (MHC) class I mediated antigen presentation observed during viral infection. Here we show that US3 and US6 encode ER-resident glycoproteins that prevent intracellular transport of NMC class I molecules by different mechanisms. US3 retains stable MHC class I heterodimers in the ER which are loaded with peptides while retained in the ER. US6 prevents MHC class I assembly with  beta 2 microglobulin which results in free heavy chains leaving the ER. These genes have the potential to prevent unwanted immunological reactivities triggered by MHC class I molecules.
Patent DE-69732523-T2 (DE)
Inventor: BEN-HAIM SHLOMO
IPC: A61B1/005
Filed: 1997-12-31
Granted: 2006-02-16
Abstract: PCT No. PCT/IL97/00448 Sec. 371 Date Apr. 12, 1999 Sec. 102(e) Date Apr. 12, 1999 PCT Filed Dec. 31, 1997 PCT Pub. No. WO98/29032 PCT Pub. Date Jul. 9, 1998An invasive probe apparatus includes a flexible, elongate probe having a distal end for insertion into the patient's body, first and second position sensors in a fixed, known relation to the distal end for generating signals responsive to their respective position coordinates and at least one contact sensor along a radial surface of the probe for generating a signal representing its contact with body tissue to be ablated by electrodes on the probe.
Patent DE-69738108-T2 (DE)
Inventor: DELESALLE LOUIS
IPC: C07K14/415
Filed: 1997-05-30
Granted: 2008-05-29
Abstract: The invention is directed to methods of making cytoplasmic male sterile chicory plants by identifying a diagnostic 347 bp fragment of the orf 522 of Helianthus annuus.
Patent DE-69811885-T2 (DE)
Inventor: RAUSCHNING KENNETH
IPC: A47J17/18
Filed: 1998-06-10
Granted: 2003-08-28
Abstract: The present invention relates to a device for peeling root vegetables. The device comprises a container (1), which at its bottom has at least two rotatably arranged discs (4), which have grating or cutting means on their upper side. According to the invention, the container (1) has a cylindrical outer wall (2), and the bottom of the container (1) is a rotatably arranged disc (3).
Patent DE-69821347-T2 (DE)
Inventor: HEYMES ALAIN
IPC: C07D495/04
Filed: 1998-05-11
Granted: 2004-12-02
Abstract: A process for the preparation of [2-(2-thienyl)-ethylamino]-(2-halogenophenyl)-acetonitriles of general formula (I) starting from 2-(2-thienyl)-ethyl-amine, alkalicyanide and o-halogeno-benzaldehyde. Compounds of general formula (I) are valuable intermediates.
Patent DE-69827913-T2 (DE)
Inventor: FIEKOWSKY PETER
IPC: G16B25/00
Filed: 1998-12-10
Granted: 2005-04-07
Abstract: Systems and methods for aligning scanned images are provided. A pattern is included in the scanned image so that when the image is convolved with a filter, a recognizable pattern is generated in the convolved image. The scanned image may then be aligned according to the position of the recognizable pattern in the convolved image. The filter may also act to remove the portions of the scanned image that do not correspond to the pattern in the scanned image.
Patent DE-69833318-T2 (DE)
Inventor: TAMURA SHINICHIRO
IPC: B41M5/26
Filed: 1998-04-23
Granted: 2006-09-07
Abstract: The present invention provides an optical recording medium including a recording layer 2 and an optical reflection layer 3 formed on a substrate 1. The recording layer 2 contains at least one particular polymethine pigment selected from polymethine pigments having 1 to 4 carbons in the methine main chain, so as to obtain a sufficient recording sensitivity for a red wavelength range of light. <IMAGE>
Patent DE-69835258-T2 (DE)
Inventor: GELDERIE UDO
IPC: C03C10/00
Filed: 1998-07-01
Granted: 2007-08-02
Abstract: The plate glass panel which is fire resistant comprises glass or glass-ceramic resistant to high temperatures, with rough, light diffusing surfaces. It is joined on both faces to silicate glass by intermediate transparent layers having a refractive index corresponding to that of the glass or glass-ceramic. The intermediate layers are made of a thermoplastic polymer which has a high effect on light flashes. The silicate glass is soaked by thermal means.
Patent DE-69837896-T2 (DE)
Inventor: SCHLOM JEFFREY
IPC: A61P35/00
Filed: 1998-09-22
Granted: 2008-02-14
Abstract: The present invention relates to the preparation and use of peptides that act as agonists and antagonists of human carcinoembryonic antigen (CEA). Agonists of the CEA peptide, CAP1, are disclosed and their utility in enhancing immune responses against CEA demonstrated.
Patent DE-69905288-T2 (DE)
Inventor: ODDOU LAURENT
IPC: H05K3/28
Filed: 1999-11-29
Granted: 2003-10-09
Abstract: A method for making a contactless chip card of the type having an electronic module, and an antenna connected to the module, includes the following steps: producing, on a first support sheet, the antenna with connection terminals provided at its ends; producing an insulating bridge partly covering the antenna coils except for the connection terminals; depositing a drop of filling material on the insulating bridge; transferring the electronic module, with its connection pads being oriented towards the insulating bridge; and providing an electric connection between the module contact pads and the antenna connection terminals.
Patent DE-69910430-T2 (DE)
Inventor: SOAS THIERRY
IPC: B05C1/08
Filed: 1999-12-07
Granted: 2004-03-11
Abstract: A method and device for continuously coating at least a metal strip (1) with a crosslinkable polymer fluid film which is free of non-reactive solvent or diluent, and which has a softening temperature higher than 50° C. The method includes the steps of: continuously unwinding the metal strip (1) on at least a back-up roll (30); forming, by forced flow on an applicator roll (20) having a deformable surface, a layer of the crosslinkable polymer; and forming on the applicator roll (20) the crosslinkable polymer film and transferring the film from the applicator roll onto the metal strip. The device implements this method.
Patent DE-69911050-T2 (DE)
Inventor: MENEGUZZO ENZO
IPC: C09D11/10
Filed: 1999-11-05
Granted: 2004-07-08
Abstract: The present invention relates to compounds of general formula (I)whereinX1 and X2 are different form each other and have the meanings reported in the following descriptionY is a simple bond, C1-C12 linear or branched alkyl groups, -O-, -S-, >S=O, >SO2, NR17-, wherein R17 is H, C1-C12 linear or branched alkyl groups, COR1, and photopolymerisable formulations containing as photoinitiators the aforementioned compounds of formula (I).
Patent DE-69912100-T2 (DE)
Inventor: INNALA MATTI
IPC: D21G9/00
Filed: 1999-02-17
Granted: 2004-05-19
Abstract: A method and apparatus for reeling or winding of a web in which one or more factors affecting the web in the reeling or winding process are controlled by means of measurement data in order to affect the quality of the reel or roll formed in the reeling or winding process. The is measurement data used is the web tension profile of the web brought into the reeling. The web tension profile is measured by means of a measuring device from which the web tension profile data is transmitted to a data processing unit which adjusts the factors affecting the web during reeling or winding.
Patent DE-69921998-T2 (DE)
Inventor: LEE MAW-CHWAIN
IPC: G01N1/08
Filed: 1999-09-20
Granted: 2005-11-10
Abstract: An automatic sampling method and facility are disclosed, by means of which multiple samples are obtained from a closed container filled with heterogeneous solid material. The sampling points are predetermined and well distributed on the container and the sampling position and depth in the container are selected by a special controller of the sampling system. The system can be operated at an open space for non-radioactive material. The obtained samples are collected and blended in a mixer for homogenization treatment to produce a final specimen for analytical measurement . The homogeneous specimen is well accepted for its representative character.  <IMAGE>
Patent DE-69927461-T2 (DE)
Inventor: WANG LUPING
IPC: F17C7/00
Filed: 1999-04-28
Granted: 2006-06-22
Abstract: A fluid storage and dispensing system (10) comprising a vessel (12) for holding a fluid (17) at a desired pressure. The vessel has a pressure regulator (26) set at a predetermined pressure. The regulator may be interiorly or exteriorly positioned, single-staged or multi-staged, and is associated with a port of the vessel. A dispensing assembly, e.g. including a flow control means such as a valve (20), is arranged in gas/vapor flow communication with the regulator (26), whereby the opening of the valve effects dispensing of gas/vapor from the vessel (12). The fluid in the vessel may be constituted by a liquid that is confined in the vessel at a pressure in excess of its liquefaction pressure at prevailing temperature conditions, e.g. ambient (room) temperature.
Patent DE-69932831-T2 (DE)
Inventor: LAMBERT ANDRE
IPC: B29C45/00
Filed: 1999-09-14
Granted: 2007-03-29
Abstract: The process involves injecting into mold a composition comprising thermoplastic matrix in form of thermoplastic polymer A, reinforcing filler in form of fibrous substance B with factor L/D above 20, fine filler C with form factor L/D below 20, and nucleation agent D. Substance B is selected from glass, ceramic, carbon and thermoplastic polymer fibers, while C is selected from mineral fillers such as glass spheres, ground glass, glass scales or their mixtures. The process involves injecting into mold a composition comprising thermoplastic matrix in form of thermoplastic polymer A, reinforcing filler in form of fibrous substance B with factor L/D above 20, fine filler C with form factor L/D below 20, and nucleation agent D. Substance B is selected from glass, ceramic, carbon and thermoplastic polymer fibers, while C is selected from mineral fillers such as glass spheres, ground glass, glass scales or their mixtures. Thermoplastic composition preferably contains 10-60 wt.% of total B + C fillers and wt. ratio of C to B is 0.2-10. The content of D is preferably below 1 wt.% per total wt. of composition. The composition may also contain additives such as pigments, colorants, thermo- and/or photo-stabilizers, and durability modifiers.
Patent DE-69935538-T2 (DE)
Inventor: SEKIYA HIROSHI
IPC: B01F27/94
Filed: 1999-10-18
Granted: 2007-12-06
Abstract: There is disclosed a stirring device (1) in which oil rising is prevented, and an adverse influence onto oil sealing bellows (53,58) by a pressure rise accompanying the temperature rise of the crank chamber (26) is prevented. The oil sealing bellows (53,58) are disposed between a space in a housing (25,26) and compression and expansion cylinders, and a buffer tank (59,60) provided with the pressure adjusting bellows (61,62) is disposed between a space on the back surface side of the compression and expansion pistons (69,70) and the space in the housing (25,26), so that the pressure rise in the housing and the pressure fluctuation of the space are absorbed.
Patent DE-69938195-T2 (DE)
Inventor: HERBERT DAVID CHARLES WILFRED
IPC: H01L31/107
Filed: 1999-12-17
Granted: 2008-06-12
Abstract: The present invention provides an avalanche photo-diode detector arrangement comprising two avalanche photo-iodes, which are each reverse biased to just below their breakdown voltage, are arranged back-to-back and are arranged in series with an oscillating voltage source such that the photodiodes exceed their breakdown voltage out of phase with each other. The oscillating voltage has a period of at least twice and preferably between 4 and 32 times, the avalanche zone transit time of the photo diodes. The detector arrangement achieves low noise and is able to distinguish dark counts.
Patent HU-E026503-T2 (HU)
Title: Method of determining motion vectors of direct mode in a B Picture
Inventor: JEON BYEONG MOON
IPC: H04N19/46
Filed: 2003-01-07
Abstract: The present invention relates to a method of determining motion vectors of direct mode in a B picture, in which when processing each block in the B picture using the direct mode, motion vectors of the direct mode for the B picture are determined differently according to a kind of a reference buffer storing a reference picture pointed to by a motion vector of a co-located block in a specified picture.
Patent HU-E035411-T2 (HU)
Title: Arrangement and method for burning fuel
Inventor: HONKOLA TIMO
IPC: C10J3/56
Filed: 2014-09-03
Abstract: An arrangement and a method for burning fuel. The arrangement (1) comprises gasification equipment (3) for converting fuel (F) into product gas (G) by gasification and a combustion plant (5) for burning the product gas (G). The gasification equipment (3) comprises means for gasifying fuel at a low temperature. The arrangement (1) also comprises a separator (4) arranged between the gasification equipment (3) and the combustion plant (5) so that substantially all product gas (G) conveyed into the combustion plant flows from the gasification equipment (3) through the separator into the combustion plant (5). The separator (4) comprises means for purifying the product gas (G) of solids.
Patent MD-3394084-T2 (MD)
Inventor: MAHR ANDREA
IPC: C07K16/28
Filed: 2016-11-29
Abstract: Prezenta invenţie se referă la peptide, proteine, acizi nucleici şi celule pentru utilizare în metode imunoterapeutice. În mod special, prezenta invenţie se referă la imunoterapia cancerului. În plus, prezenta invenţie se referă la epitopii peptidici ai celulelor T citotoxice asociate tumorii, singuri sau asociaţi cu alte peptide asociate tumorii, care pot servi, de exemplu, drept componentele farmaceutice active ale formulelor de vaccin care stimulează răspunsurile imunitare antitumorale sau pentru stimularea celulelor T ex vivo şi transferarea în pacienţi. Peptidele legate de molecule ale complexului major de histocompatibilitate (MHC), sau peptidele ca atare, pot fi, de asemenea, ţinte ale anticorpilor, ale receptorilor solubili ai celulelor T şi ale altor molecule de legare
Patent TR-200001021-T2 (TR)
Title: Aktif maddelerin kontrollü salınması için biyo aşındırılabilir makromerler.
Inventor: HUBBELL JEFFREY A
IPC: A61K9/22
Filed: 1998-07-17
Abstract: Biyolojik olarak aktif bir maddenin verilmesi için bir metod açiklanmaktadir, su asamalari içerir;(a) sözü edilen biyolojik olarak aktif maddenin bir makromer ile birlestirilmesi,(b) önceki asama (a)'da olusturulan kombinasyonun bir karisiminin, (c) sözü edilen karisimin polimerlestirilmesi ve (d) sözü edilen madde ya da onun bir parçasinin bir memeliye uygulanmasi, burda asama (c) bir polimerlestirilebilir monovinil monomer olmadan gerçeklesir.
Patent TR-200001179-T2 (TR)
Inventor: ASTLES PETER CHARLES
IPC: A61P19/02
Filed: 1998-11-02
Abstract: The invention is directed to physiologically active compounds of formula (I):wherein:R1 is hydrogen, halogen, hydroxy, lower alkyl or lower alkoxy;X1, X2 and X6 independently represent N or CR10; andone of X3, X4 and X5 represents CR11 and the others independently represents N or CR10;where R10 is hydrogen, amino, halogen, hydroxy, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulphinyl, lower alkylsulphonyl, nitro or trifluoromethyl; and R11 represents a group -L1-Ar1-L2-Y; and the corresponding N-oxides, and their prodrugs; and pharmaceutically acceptable salts and solvates of such compounds and their N-oxides and prodrugs. Such compounds have valuable pharmaceutical properties, in particular the ability to regulate the interaction of VCAM-1 and fibronectin with the integrin VLA-4 (alpha4beta1).