baber/WOPTO huggingface dataset:
Patent DE-60138056-D1 (DE)
Inventor: RENARD MARTIAL
IPC: G01N33/542
Filed: 2001-03-01
Granted: 2009-04-30
Abstract: A biosensor comprising at least a fragment of a protein receptor ready to bind to a suitable ligand at an active site and in which fragment, at least one of its amino acid residues located near the active site is a naturally present or substituted Cys, and having a fluorophore coupled to that Cys, is new. Independent claims are included with the following: (i) a protein-based chip comprising a solid support carrying the above immobilized biosensor; (ii) preparing the above biosensor, comprising: (a) selecting by research receptor the residues which, in the receptor-ligand complex are in direct contact with the ligand, or in contact by an intermediary water molecule, or whose surface accessible to solvent (ASA) is modified by binding or the ligand when using spheres of 1.4 -30, more preferably 1.4 - 2.9 angstroms for the solvent; (b) calculating accessibility to the solvent for the free receptor of atoms in positions gamma and eventually in position delta for each residue selected in (a) by using a 1.4 angstrom sphere, and selecting residues where the atom in position gamma or delta is accessible to the solvent (c) directly changing at least one of the residues selected in (b) to a Cys residue where the residue is not naturally Cys; and (c) coupling the S g atom of at least one of the Cys residues obtained in (b) or (c) with a fluorophore; (iii) preparing the claimed biosensor, comprising: (a) identifying the receptor active site mutating the whole, or a sub-set of the residues located in the vicinity of the active site and determining variations in the parameters of the interaction with the ligand (KD, k on, k off) due to each mutation or limited groups of changes (b) selecting Cys residues or residues changed to Cys situated in the vicinity of the active site along the sequence (c) directly changing at least one of the residues selected in (b) to a Cys where the residue is not naturally Cys; and (b) coupling the S g atom of at least one of the Cys residues obtained in (b) or (c) with a fluorophore; (iv) plasmid pMR1 having the sequence fully defined in the specification and deposited under CNCM number I-2386, or its derivative; (v) plasmid pMR1(VL-S93C) having the sequence fully defined in the specification and deposited under CNCM number I-2387, to prepare the claimed biosensor; (vi) a reagent for detecting, quantifying or localizing ligands, comprising at least the claimed biosensor; (vii) detecting, quantifying or localizing a ligand in a heterogeneous sample, comprising contacting the sample with the above reagent; and (viii) a kit for detecting inhibitors of ligand-receptor interactions comprising the above reagent.
Patent DE-60142032-D1 (DE)
Inventor: BRUENING RONALD L
IPC: C07C229/08
Filed: 2001-03-09
Granted: 2010-06-17
Abstract: Naphthyl crown ether ligand molecules containing at least two naphthyl groups that are covalently bonded to suitable solid supports and coated by hydrophobic organic solvents are disclosed. These compositions and associated methods are characterized by selectivity of desired amine or amino acid enantiomers over their counter-enantiomers and derivatives. The composition preferably has an alpha-value greater than or equal to 4. This allows for the separation of such enantiomers with nonchromatographic resin bed separations of three separation stages or less.
Patent DE-60201340-D1 (DE)
Inventor: KRETSCHMER PETER
IPC: C08F4/643
Filed: 2002-03-05
Granted: 2004-10-28
Abstract: The invention relates to a catalyst component and a catalyst system for the preparation of high molecular weight ethylene or alpha-olefin homopolymers, ethylene-alpha-olefin copolymers, terpolymers or tetrapolymers, in a polymerization process, which is expediently effected in solution, at elevated temperature, preferably at least 80 DEG C. The catalyst system comprises a group 4-6 metal, preferably group 4 metal, a cyclic ligand (such as a cyclopentadienyl-type ligand), which forms a delocalized pi-bond with the metal M, a monohapto bonded 1,3-diaza-2-imino heterocyclic ligand (such as an iminoimidazolidine-type ligand) and anionic ligands and a catalyst activator coupound.
Patent DE-60202794-D1 (DE)
Inventor: GENDROT EDOUARD
IPC: A61P29/00
Filed: 2002-10-28
Granted: 2005-03-03
Abstract: The invention relates to a rapid-disintegrating tablet of the type which is intended to disintegrate in the mouth on contact with the saliva in less than 40 seconds, preferably in under 30 seconds, and which forms an easy-to-swallow suspension. The inventive tablet is made from at least one active material which takes the form of coated microcrystals or microgranules and a mixture of excipients in the form of grains. The aforementioned mixture of excipients has the following composition: between 60 and 85% of a diluent; between 3 and 20% of a decomposing agent; between 1 and 8% of a sweetening agent; between 0 and 5% of a gliding agent; between 0 and 10% of a binder; and between 0 and 10% of a permeabilising agent, a swelling agent and/or a lubricant. The above-mentioned percentages are weight percentages in relation to the total weight of the grains of the excipients. Said excipient grains have a median particle size of between +30 and -30 %, and preferably between +10 and -10%, in relation to the dimension of the coated microcrystals or microgranules.
Patent DE-60207697-D1 (DE)
Inventor: TONCICH SLAVKO
IPC: H03F3/191
Filed: 2002-04-02
Granted: 2006-01-05
Abstract: The present invention quantifies and reduces losses in tunable bandpass filters having ferro-electric capacitors. Given a required insertion loss and the quality factor of a resonator, the geometric losses resulting from a particular topology for the ferro-electric capacitor and the metal losses are accounted for to quantify the allowable ferro-electric losses.
Patent DE-60208411-D1 (DE)
Inventor: MERZEAU JULIEN
IPC: B65D71/00
Filed: 2002-10-18
Granted: 2006-02-02
Abstract: A carton and blank (10) for forming a carton for holding a plurality of articles. The carton includes a series of hinged wall panels forming a sleeve including a top panel (16) and opposed side panels (14, 18) hingedly connected to the top panel (16). There further comprises a continuous strap handle (H) formed from the carton and transversely extending entirely across the top panel (16) and one of the side panels (14). The strap (H) is so connected at its opposite ends as to provide a surplus of material to enable a user part of the handle (H) to be brought into a position of use.
Patent DE-60208528-D1 (DE)
Inventor: ZOPPETTI GIORGIO
IPC: A61K31/715
Filed: 2002-02-26
Granted: 2006-03-30
Abstract: The purification of the E. coli K5 polysaccharide by treatment with isopropyl alcohol and elimination of lipophilic substances is described. The purified product can be used to prepare, after N-deacetylation, new N,O-sulfated polysaccharides with high degree of sulfation.
Patent DE-60211680-D1 (DE)
Inventor: SCHLOTHAUER RALF-CHRISTIAN
IPC: A23L27/10
Filed: 2002-04-19
Granted: 2006-06-29
Abstract: The method of the invention produces a savoury flavoured product from a source of protein using a combination of two distinct strains of bacteria. The source of protein may be a plant   soy, wheat or rice- but is preferably milk or whey. The first strain of bacteria is selected from the group Macrococcus, Micrococcus, Entercoccus, Staphylococcus, Brevibacterium, Anthrobacter and Corynebacterium, preferably Macrococcus caseolyticus. The second strain of bacteria is selected from the lactic acid bacteria - Lactococcus, Lactobacillus, Pediococcus or Leuconostoc. The protein source is fermented with the bacteria at a pH above the isoelectric point of the protein, preferably at a pH of 5.5-6.5. The savoury flavoured product may be combined with other ingredients to form products such as cheese, protein-water gels, yoghurts, creams, custards, sauces and confectionary products.
Patent DE-60213838-D1 (DE)
Inventor: BOYLE R
IPC: G01F15/00
Filed: 2002-09-03
Granted: 2006-09-21
Abstract: A system for delivering a preset volume of fluid, such as oil, includes a master control station (1) and one or more metering devices (8) communicatively linked through a wireless communications network. The master control station (1) provides command signals to enable dispensing of a fluid from the metering device (8) and provides a preset amount of fluid to be dispensed. The metering device (8) is manually activated by a manually-operated lever (14), and is thereafter latched in an open position to dispense lubricant. The amount of lubricant dispensed is metered until the predetermined amount of lubricant is dispensed. After the preset amount is dispensed, the metering device (8) is latched in a closed position, preventing further dispensing until the metering device (8) is again enabled by the master control station (1).
Patent DE-60222127-D1 (DE)
Inventor: WOOD ROLAND A
IPC: G01J5/24
Filed: 2002-06-18
Granted: 2007-10-11
Abstract: A method and apparatus to reduce undesirable deficiencies in an image produced by a microbolometer array including multiple smaller arrays includes applying a separate bias pulse to each of the microbolometers in the smaller arrays and measuring a resulting signal corresponding to the applied bias pulse for each of the microbolometers using multiple measurement circuits associated with the smaller arrays during the frame time. Further, one or more known bias pulses are applied to the measurement circuitry during the frame time, one or more resulting calibration signals are measured, an offset parameter for each of the smaller arrays based on the corresponding measured resulting calibration signals is computed, and the measured resulting signal is corrected using the associated computed offset parameter to produce an output signal that reduces the undesirable deficiencies in the image produced by the array.
Patent DE-60223869-D1 (DE)
Inventor: ARMSTRONG STEPHEN WADE
IPC: G01R29/04
Filed: 2002-04-18
Granted: 2008-01-17
Abstract: A digital quasi-RMS detector is provided that approximates the time-varying RMS energy of a signal. The digital quasi-RMS detector rectifies the signal and compares the rectified signal with an estimated present energy value of the audio signal. If the difference between the rectified signal and the estimated present energy value is not greater than zero, then the digital quasi-RMS detector multiplies the rectified signal by a first time constant to generate a first filtered signal and sums the first filtered signal with the estimated present energy value to determine the approximate RMS energy. If the difference between the rectified signal and the estimated present energy is greater than zero, however, then the digital quasi-RMS detector multiplies the rectified signal by a second time constant to generate a second filtered signal and sums the second filtered signal with the estimated present energy value to determine the approximate RMS energy. <IMAGE>   <IMAGE>
Patent DE-60224205-D1 (DE)
Inventor: MORINI GIAMPIERO
IPC: C08F110/06
Filed: 2002-09-04
Granted: 2008-01-31
Abstract: The present invention relates to a solid catalyst component for the polymerization of olefins CH<SUB>2</SUB>-CHR in which R is hydrogen or a hydrocarbon radical with 1-12 carbon atoms, comprising Mg, Ti, halogen and an electron donor selected from maleates of a particular formula. Said catalyst components when used in the polymerization of olefins, and in particular of propylene, are capable to give polymers in high yields and with high isotactic index expressed in terms of high xylene insolubility.
Patent DE-60224783-D1 (DE)
Inventor: SAUVONNET FRANCK
IPC: B60T7/06
Filed: 2002-02-18
Granted: 2008-03-13
Abstract: A brake pedal ( 1 ) for a vehicle, in particular, a motor vehicle, includes a framework structure ( 2 ) mounted for rotation about a first rotation spindle ( 3 ) connectable to the bulkhead of the vehicle. A peg ( 5 ) is fixed to one end ( 4 a) of a pedal web ( 4 ) and slides in a slot ( 21 ) provided in the framework structure ( 2 ). A movement mechanism ( 7 ) causes the peg to slide in the slot, defining a length (L) between the rotation spindle of the framework structure and the other end ( 4 b) of the pedal web. A first link ( 8 ) is connected to the framework structure and is mounted for rotation about a second rotation spindle ( 9 ) connectable to the bulkhead of the vehicle. The first link includes a connection ( 13 ) for receiving an end of the rod of the brake booster of the vehicle at a distance (R) from the second rotation spindle. The brake pedal operates to provide a constant step-down ratio (L/R).
Patent DE-60226729-D1 (DE)
Inventor: FRESKOS JOHN
IPC: C07B51/00
Filed: 2002-05-31
Granted: 2008-07-03
Abstract: Disclosed are compounds of formula X, which are useful in treating Alzheimer's disease and other similar diseases. Pharmaceutical compositions comprising compounds of formula X and methods of preparing the compounds of formula X are also disclosed.
Patent DE-60229869-D1 (DE)
Inventor: XIAO JIAN MING
IPC: G01J3/12
Filed: 2002-09-06
Granted: 2008-12-24
Abstract: A spectrograph with a first concave spectrographic diffraction grating is positioned to receive light from the input light source is configured to provide a diffracted light output dispersing the components of the input light source in a first direction. The dispersion forms the input light into an intermediate spectra. The intermediate spectra is formed in a focal surface by the once diffracted light. A slit is substantially positioned on the focal surface. A second concave diffraction grating is positioned to receive once diffracted light from the slit and configured to provide a twice diffracted light output, the second concave diffraction grating dispersing the components of the input light source in a second direction. The second direction is different from the first direction, the dispersion forming the input light into an output spectra.
Patent DE-60238410-D1 (DE)
Inventor: LINDERHOLM DAG
IPC: B23C1/06
Filed: 2002-07-10
Granted: 2011-01-05
Abstract: An orbital machining apparatus for producing a hole in a workpiece using a cutting tool and including a first actuator for rotating the cutting tool about its longitudinal center axis, a second actuator for moving the cutting tool in an axial feed direction, a third actuator for rotating the cutting tool about a principal axis and a radial offset mechanism. The radial offset mechanism includes an inner cylindrical body having an eccentric cylindrical hole and which supports a spindle unit, the inner cylindrical body radially supported in an eccentric cylindrical hole of an outer cylindrical body to adjust the radial distance of the cutting tool longitudinal center axis from the principal axis. The third actuator includes first and second motors which rotate the outer and inner cylindrical bodies, respectively, in synchronism to maintain a mutual rotary position thereof to keep a cutting tool radial offset position unchanged during operation.
Patent DE-60238965-D1 (DE)
Inventor: ABRILES BETH KWIATKOWSKI
IPC: C23G5/00
Filed: 2002-11-28
Granted: 2011-03-03
Abstract: The present invention relates to a maskant system for use with a fluoride cleaning system. The maskant system comprises a parting compound applied to a surface which requires protection and a chromium rich maskant for substantially preventing intergranular attack and which reduces a depletion zone. The parting compound contains colloidal silica, de-ionized water, fused alumina grains, and alumina powder. The maskant is comprised of chromium powder mixed with a binder, a wetting agent, a thickening agent, and water. The maskant system may be used to clean components formed from nickel-based or cobalt-based alloys using a fluoride cleaning system and has particular utility when components formed from single crystal nickel based alloys are cleaned using a fluoride cleaning system.
Patent DE-60303819-D1 (DE)
Inventor: TOUCHAIS SANDRINE
IPC: H03F1/32
Filed: 2003-10-28
Granted: 2006-04-27
Abstract: The method involves generating a radio frequency amplifier linearization training sequence with symbols and transmitting the sequence using a transmitter. The sequence includes automatic gain control sequence (55) to adjust parameters of transmission links between mobile terminal and base station of a radio communication system. The transmitted sequence is compared with the generated sequence to carry the linearization.  Independent claims are also included for the following:  (a)  a training device of a linearization device of radio frequency amplifier (b)  a mobile terminal of radio communication system (c)  a base station of a radio communication system.
Patent DE-60306600-D1 (DE)
Inventor: GOODWIN KEVIN
IPC: H02G7/05
Filed: 2003-08-26
Granted: 2006-08-17
Abstract: A cable hanger for securing multiple cables to support structures including antenna towers and poles. The cable hanger has a hingeably-coupled pair of shell halves with recesses that, when folded, establish a pair of cable passageways. Gripping arms provided on each of the shell halves project into a corresponding one of the cable passageways for gripping a cable positioned therein. Pairs of gripping arms located on opposite shell halves have a confronting relationship for gripping the cable on diametrically opposite side surfaces. <IMAGE>
Patent DE-60306989-D1 (DE)
Inventor: ANGHILERI GIANMARIO
IPC: B65D3/06
Filed: 2003-05-21
Granted: 2006-09-07
Abstract: A frustoconical container of paper material for sweet goods, cakes or foodstuffs in general comprising a bottom (2) of a substantially circular contour and a side wall (3) having a pleated area (4); the side wall (3) comprises at least one substantially flat band (8) interposed in the pleated area (4) and delimited, at the bottom, by a rectilinear stretch corresponding to a rectilinear stretch (8a) of the bottom (2). <IMAGE>
Patent DE-60308388-D1 (DE)
Inventor: WHITE J
IPC: C07J21/00
Filed: 2003-03-21
Granted: 2006-10-26
Abstract: The present invention provides 5-androsten-3beta-ol steroid intermediates and processes for their preparation.
Patent DE-60309148-D1 (DE)
Inventor: HOTTNER MARTIN
IPC: A41D27/24
Filed: 2003-06-27
Granted: 2006-11-30
Abstract: Joining two waterproof laminate pieces to form welded seam (80) involves placing laminates together so that textile layers contact one another and edges (60a, 60b) of the laminates (1a, 1b) are aligned with each other to form an edge area (65); welding and pressing the edge area together to form seam between the pieces; and welding and pressing the seam together to reorient the edges of the laminates in an edge-to-edge butted orientation. Each of the laminate comprises at least a waterproof functional layer (50) laminated to a textile layer (30). The textile layer has two components. The first component is stable to a first temperature (preferably 180[deg]C) and the second component melts at a second temperature (preferably 160 - 230[deg]C) lower than the first temperature. Welding and pressing the edge area and seam is carried out at 160 - 230[deg]C, using ultrasonic energy in a continuous process.
Patent DE-60320942-D1 (DE)
Inventor: HSU RAYMOND T
IPC: G06F13/00
Filed: 2003-01-28
Granted: 2008-06-26
Abstract: A method and apparatus for negotiating capability information for a broadcast service in a communication system. In one embodiment, the generic capabilities are pre-configured in BSC, which provides the generic capability information to MS and to PDSN based on a listing of available BC services and the corresponding capabilities. Another embodiment pre-configures PDSN with the generic capability information. According to still another embodiment, PDSN is pre-configured with the generic capability information, wherein the MS queries the PDSN directly for generic capability information via a PPP connection. In yet another embodiment, the MS queries the PCF, which in turn queries all of the PDSN in the system. The PDSN responsible for the BC responds to the query. Where multiple PDSNs may support the BC, the first to respond using multicast addressing obviates the need for the others to respond.
Patent DE-60321619-D1 (DE)
Inventor: BOUBAL MICHEL
IPC: G06K9/32
Filed: 2003-04-29
Granted: 2008-07-31
Abstract: The method of extraction of an illuminated area of a light detector photocell matrix of a missile guidance sensor involves dividing a matrix domain (RO) into search zones (r1-R1D) and analyzing theses zones with respect to each other with the aid of a global function to detect the presence of an active light cell (3E-H). If an active dell is detected, the search is restarted with a new area.  The stages are repeated to obtain a matrix domain composed entirely of active cells.
Patent DE-60324424-D1 (DE)
Inventor: TODOLI SILVANO
IPC: F23D14/06
Filed: 2003-09-05
Granted: 2008-12-11
Abstract: The present invention refers to a gas burner, in particular for domestic cooking appliance, comprising a bowl-shaped body (10) associated with a gas injector (11) herein assembled, a mini-Venturi inlet within said bowl-shaped body, a toothed crown (12) with a plurality of flame ports (13) placed over said body and extending to an external lateral surface, an upper cap (14) having substantially the same diameter of the toothed crown (12) to close the burner top so that to identify a single lateral flame ports plane, and a peripheral step (15) formed on at least a part of the external surface of the toothed crown (12).
Patent DE-60325907-D1 (DE)
Inventor: EKSTROEM BO
IPC: H04L12/26
Filed: 2003-09-05
Granted: 2009-03-05
Abstract: The present invention relates to a method for monitoring media flow in a telecommunication network. The network comprises a media-handling node (MHN) through which, sessions between subscribers are transported via first ports (PI1-PI5) and second ports (PO1-PO5). An extra port (XP1-XP5) is assigned to the media-handling node (MHN) for each new session that is transported through the node. The method comprises the following steps: storing in a database (LI-DB), identification of a first subscriber (A) for which monitoring is desired; a connection is set-up between the first subscriber (A) and second subscriber (B); an assigned extra port (XP1) that is adherent to the session between the first and second subscriber (A, B) is connected; the session between the first and second subscriber is monitored via the connected extra port (XP1).
Patent DE-68907702-D1 (DE)
Inventor: SUNDSTEDT GERT
IPC: C22C37/04
Filed: 1989-12-12
Granted: 1993-08-26
Abstract: The present invention discloses a roll ring for hot and/or cold rolling. The rolling track comprises one or several cemented carbide rings, which are cast into a casing made by an iron alloy. The cast alloy comprisin'g a materially graphitic cast iron, which after the casting contains residual austenite. This residual austenite is at subsequent heat treatment or treatments partly or totally transformed under volume increase to mainly bainite with the aim of reducing or totally eliminating the differential shrinkage between the cast iron and the cemented carbide as a result from cooling after the casting.