baber/WOPTO huggingface dataset:
Patent AU-2005212399-B2 (AU)
Title: Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
Inventor: BENJAMIN NICHOLSON
IPC: C07D407/14
Filed: 2005-02-04
Granted: 2011-09-22
Abstract: Compounds represented by the following structure (I) are disclosed: as are methods for making such compounds, wherein said methods comprise reacting a diacyldiketopiperazine with a first aldehyde to produce an intermediate compound; and reacting the intermediate compound with a second aldehyde to produce the class of compounds with the generic structure, where the first aldehyde and the second aldehydes are selected from the group consisting of an oxazolecarboxaldeyhyde, imidazolecarboxaldehyde, a benzaldehyde, imidazolecarboxaldehyde derivatives, and benzaldehyde derivatives, thereby forming the above compound wherein R, R', R'', R, R, R, R, and R, X and X, Y, Z, Z, Z, Z, and Z may each be separately defined in a manner consistent with the accompanying description. Compositions and methods for treating vascular proliferation are also disclosed.
Patent AU-2005249493-B2 (AU)
Title: Diarylalkanes as potent inhibitors of binuclear enzymes
Inventor: ZHAO JI-FU
IPC: A61K31/05
Filed: 2005-05-27
Granted: 2011-09-08
Abstract: The present invention implements a strategy that combines an enzyme inhibition assay with a chemical dereplication process to identify active plant extracts and the particular compounds - diarylalkanes and/or diarylalkanols within those extracts that specifically inhibit binuclear enzyme function. Included in the present invention are compositions of matter comprised of one or more of diarylalkanes and/or diarylalkanols, which inhibit the activity of binuclear enzymes, particularly tyrosinase and which prevent melanin overproduction. The present invention also provides a method for inhibiting the activity of a binuclear enzyme, particularly tyrosinase and a method for preventing and treating diseases and conditions related to binuclear enzyme function. The present invention further includes a method for preventing and treating melanin overproduction and diseases and conditions of the skin related thereto. The method for preventing and treating diseases and conditions related to binuclear enzyme function and melanin overproduction is comprised of administering to a host in need thereof an effective amount of a composition comprising one or more diarylalkanes and/or diarylalkanols synthesized and/or isolated from one or more plants together with a pharmaceutically acceptable carrier.
Patent AU-2005286164-B2 (AU)
Title: Monoclonal antibodies to progastrin
Inventor: GRIMES STEPHEN
IPC: C07K16/26
Filed: 2005-09-21
Granted: 2012-05-24
Abstract: The present invention provides progastrin-binding molecules specific for progastrin that do not bind gastrin-17(G17), gastrin-34(G34), glycine-extended gastrin-17(G17-Gly), or glycine-extended gastrin-34(G34-Gly). Further, the invention provides monoclonal antibodies (MAbs) selective for sequences at the N-terminus and the C-terminus of the gastrin precursor molecule, progastrin and the hybridomas that produce these MAbs. Also provided are panels of MAbs useful for the detection and quantitation of progastrin and gastrin hormone species in immuno- detection and quantitation assays. These assays are useful for diagnosing and monitoring a gastrin-promoted disease or condition, or for monitoring the progress of a course of therapy. The invention further provides solid phase assays including immunohistochemical (IHC) and immunofluorescence (IF) assays suitable for detection and visualization of gastrin species in solid samples, such as biopsy samples or tissue slices. The progastrin-binding molecules are useful therapeutically for passive immunization against progastrin in progastrin-promoted diseases or conditions. Also provided are surrogate reference standard (SRS) molecules that are peptide chains of from about 10 to about 35 amino acids, wherein the SRS molecule comprises at least two epitopes found in a protein of interest of greater than about 50 amino acids. Such SRS molecules are useful as standards in place of authentic proteins of interest.
Patent AU-2005306021-B2 (AU)
Title: Membrane unit, housing of a pressure measuring unit and pressure measuring unit
Inventor: MARCO CARONNA
IPC: A61M1/36
Filed: 2005-11-10
Granted: 2011-08-18
Abstract: The present invention relates to a membrane unit adapted for use in a housing of a pressure measuring unit preferably for measuring pressure in an extra-corporal blood circuit comprising a flexible membrane and a fixing ring which is integral with the membrane so that the membrane and the fixing ring form a one-piece element, wherein the fixing ring has a lower flexibility than the membrane and wherein the fixing ring comprises fixing elements for fixing the fixing ring to the pressure meas­uring housing. The invention further relates to a housing as well as to a pressure measuring unit.
Patent AU-2005317139-B2 (AU)
Title: Stacked cargo securing device and method of use
Inventor: BENO WIEBE MARVIN
IPC: B61D45/00
Filed: 2005-12-14
Granted: 2011-10-27
Abstract: A load securing device for stacked cargo comprises a body member having contact surfaces adapted to engage a side portion of each of a pair of stacked cargo items. One end of a flexible member such as a strap is attached to the body member. The flexible member extends through a space created between the stacked items, with its other end being secured to a carrier supporting the stacked items. Optimally, and when expecting forces to be applied to both sides of the stacked items, a load securing device is placed on either side of the stacked items so that forces arising during the transport of the stacked items are resisted in both directions.
Patent AU-2006206456-B2 (AU)
Title: Water-soluble film article having salt layer, and method of making the same
Inventor: DENOME FRANK W
IPC: C08J7/052
Filed: 2006-01-20
Granted: 2009-06-18
Abstract: Water-soluble articles such as films, which can be made resistant to contact with small amounts of water, and methods of making the same are disclosed. The water-soluble article is formed from a water-soluble film-forming composition, such as polyvinyl alcohol, and includes a salt that is distributed more closely to at least one of the surfaces than throughout its thickness.
Patent AU-2006213188-B2 (AU)
Title: Production of polyunsaturated fatty acids using novel cell treatment method
Inventor: KENICHI HIGASHIYAMA
IPC: A23L33/135
Filed: 2006-02-08
Granted: 2011-09-01
Abstract: A method for isolating one compound or more than one compounds from a biomass which contains microorganisms that have produced the compound or compounds, the method comprising the following steps: (a) preparing or obtaining wet cells having an average moisture content of between 30% and 80%; (b) subjecting the wet cells to primary drying to obtain primary dried cells having an average moisture content of between 5% and 50%; (c) subjecting the primary dried cells obtained in (b) to secondary drying to obtain secondary dried cells having an average moisture content of no greater than 10%; and (d) extracting or isolating, purifying and/or refining the compound or each of the compounds from the secondary dried cells obtained in (c).
Patent AU-2006250112-B2 (AU)
Title: Impulse generator and impulse tool with impulse generator
Inventor: HARTWIG SVERKER
IPC: B25D9/12
Filed: 2006-05-19
Granted: 2011-07-28
Abstract: The invention relates to an impulse generator (2) for a rock breaking tool, which comprises a propulsion chamber (6) for receiving a pressurizeable liquid volume (8), and an in the propulsion chamber (6) received impulse piston (10), where the impulse piston (10) is arranged for transfer of pressure peaks in the liquid volume (8) into impulses in the tool (12), whereby transfer of energy from a propulsion mechanism (14) into impulses in the tool (12) is effected by volume reduction of the propulsion chamber (6), whereby the impulse piston (10) is driven forward by a pressure peak in the propulsion chamber (6). The invention also relates to a hydraulic impulse tool comprising an impulse generator (2).
Patent AU-2006265768-B2 (AU)
Title: Hinge
Inventor: HANIGAN NICHOLAS JAMES
IPC: A63F3/02
Filed: 2006-06-30
Granted: 2012-07-19
Abstract: A hinge comprising two pivoting elements adapted to hingedly join two articles, each pivoting element including attachment means for attaching to an article; wherein when attached to the two articles the hinge is rotatable with respect to the articles.
Patent AU-2006278260-B2 (AU)
Title: Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility
Inventor: STEVENS VERNON C
IPC: C12P21/08
Filed: 2006-08-08
Granted: 2012-03-08
Abstract: Antibody compositions and methods for inhibition of the effects of gonadotropin hormones are provided. Methods for treating cancer and methods for regulating fertility are provided by administration of the antibody compositions to a mammalian subject in need thereof.
Patent AU-2006320507-B2 (AU)
Title: Devices, systems, and methods for occluding a defect
Inventor: ARMSTRONG DAVID
IPC: A61B17/00
Filed: 2006-12-01
Granted: 2012-11-01
Abstract: A method of occluding a defect in a patient is provided. The method includes inserting a placement member, such as a wire guide, into a defect; advancing the placement member to a desired location; inserting the placement member into a lumen in an occluding member, such as a plug or a graft; and advancing the occluding member to the desired location by inserting the placement member into a lumen in a pusher member and pushing the occluding member with the pusher member until the occluding member reaches the desired location. Medical devices and systems for occluding defects are also provided.
Patent AU-2007207242-B2 (AU)
Title: Dry stick device and method for determining an analyte in a sample
Inventor: NYGAARD LARS
IPC: G01N33/62
Filed: 2007-01-19
Granted: 2012-08-02
Abstract: The present invention relates to a dry stick test device for the determination of an analyte in a sample by means of a chemical assay. The device comprises: (i) optionally a solid support, (ii) at least one reagent pad comprising a reagent capable of reacting with the analyte, a derivative of said analyte or an indicator compound for said analyte to provide a detectable signal when in moistened state, and (iii) a development pad which is located in contact with the at least one reagent pad, optionally between the solid support and the at least one reagent pad, said development pad comprises at least one controlling compound capable of providing a condition required for the reagent to react with the analyte to provide a detectable signal, wherein the at least one reagent pad and the development pad are arranged to avoid precipitation of sample component(s) on the top-face of the device.
Patent AU-2007210026-B2 (AU)
Title: Computer-implemented land planning system and method
Inventor: REYNOLDS JR JAMES W
IPC: G06F17/10
Filed: 2007-01-30
Granted: 2011-07-14
Abstract: A computer-implemented land planning system (figs. 1-3) is designed to generate at least one conceptual fit solution to a user-defined (fig. 1) land development problem (fig. 2). The system electronically creates at least one candidate solution to the land development problem. The candidate solution incorporates a number of engineering measurements (fig. 12, 13, 15, 16) applicable in development of an undeveloped land site. A fitness function quantitatively evaluates the candidate solution based on its fitness. A heuristic problem-solving strategy manipulates the engineering measurements of the candidate solution to achieve a more quantitatively fit solution to the land development problem. A computer output device (fig. 1) outputs to a user documentation illustrating the fit solution to the land development problem.
Patent AU-2007221867-B2 (AU)
Title: A breakable rock bolt
Inventor: CRAIG PETER HAROLD
IPC: E21D21/00
Filed: 2007-10-08
Granted: 2014-04-17
Abstract: A rock bolt comprises first and second ends. The shaft extends between the ends. The shaft incorporates a hollow metal rod including at least one breaking zone. The shaft is s arranged to break preferentially in the breaking zone when impact loading is applied to the shaft. Preferably, the at least one breaking zone is formed by profiling of the metal rod so as to create a stress concentration in the breaking zone. (11 oIll +176 -~ JOT
Patent AU-2007249792-B2 (AU)
Title: Antimicrobial therapy for bacterial infections
Inventor: NIZET VICTOR
IPC: A01N57/10
Filed: 2007-05-11
Granted: 2012-08-02
Abstract: The disclosure provides compounds and methods to treat bacterial pathogenesis, and demonstrates that the S. aureus pigment is a virulence factor and potential novel target for antimicrobial therapy.
Patent AU-2007257791-B2 (AU)
Title: Flexible conductor tube for a welding gun
Inventor: LAYMON PATRICK A
IPC: B23K9/28
Filed: 2007-06-11
Granted: 2011-11-10
Abstract: A conductor tube for use in a welding gun, and preferably a MIG welding gun, is provided that includes a plurality of flex joints. The flex joints include a body defining a proximal end portion and a distal end portion, a cap secured to the proximal end portion of the body, and an extension mounted within the distal end portion of the body, the extension being repositionable within the body. The body, the extension, and the cap are adapted for attachment to each other and to adjacent components of the welding gun. Additionally, a conductor tube for use in a welding gun includes a plurality of thermally and electrically conductive elements secured to each other and extending along a length of the conductor tube, wherein the elements are independently repositionable relative to each other.
Patent AU-2007281909-B2 (AU)
Title: Managing associations in ad hoc networks
Inventor: HUI SHEN
IPC: H04W8/00
Filed: 2007-08-06
Granted: 2011-07-07
Abstract: A first wireless devices establishes an association with a second wireless device by sending a connection request packet to a previously-discovered second wireless device. The second wireless device identifies the received packet as a connection request and responds with a connection response packet, thereby establishing an association between the first and second wireless devices. The wireless devices can then, for example, send and receive data.
Patent AU-2007293646-B2 (AU)
Title: Device for collecting and separating particles and microorganisms present in the ambient air
Inventor: VERDIER AMANDINE
IPC: C12M1/26
Filed: 2007-08-30
Granted: 2013-01-10
Abstract: Device for collecting and separating particles and microorganisms present in the ambient air, comprising intake means (36, 38) for taking air into a removable centrifugation chamber (10) forming a container for transporting a liquid specimen containing the collected particles and microorganisms, this chamber being selected from a set of chambers having different diameters corresponding to intake rates of between about 100 and 2000 litres per minute, these rates being achieved with the same intake means.
Patent AU-2007301894-B2 (AU)
Title: Method and device for inserting a drainage wick
Inventor: PEARLMAN SETH
IPC: E02D3/10
Filed: 2007-09-28
Granted: 2013-01-24
Abstract: A method of inserting a drainage wick (5) into the ground comprising the steps of: - providing a drainage wick (5) where a portion (20) of said drainage wick (5) is arranged so as to be transversely and/or longitudinally impermeable; - threading said drainage wick through an inserting tube (3); - fixing an anchorage (11) component to said drainage wick extending out of said inserting tube; - driving said anchorage component, said drainage wick (5) and said inserting tube (3) downwardly into the ground; and - pulling up said inserting tube (3) whereby said anchorage component (11) and said drainage wick (5) are permitted to remain into said ground.
Patent AU-2007326900-B2 (AU)
Title: Burner with means for changing the direction of fuel flow
Inventor: SKAARUP JENSEN LARS
IPC: F23C7/00
Filed: 2007-10-22
Granted: 2012-12-13
Abstract: A description is given of a burner for introducing solid, liquid or gaseous fuel to a burning zone of a kiln, such as a rotary kiln for manufacturing cement clinker or the like, said burner comprising a number of substantially concentric ducts (1, 2, 3), being parallel to the main axis B3 of the burner, for conveying fuel and primary air to nozzle openings, as well as a number of additional ducts (4, 6, 7, 8) for conveying solid, fluid or gaseous fuel to separate nozzle openings, said additional ducts being located in the central part (10) of the burner. The burner is characterized in that it comprises means (4a, 5) for changing the flow direction of the fuel which is introduced via at least one of the additional ducts in the central part (10) of the burner, relative to the main axis B3 of the burner, at least in an ascending direction. This will allow the individual fuel particles to travel in a curved, approximately ballistic path, thereby extending the time they can be maintained in the flame. Another advantage of this configuration of the burner is that the large particles will attain the highest, and hence the longest, path, since the path of the smaller particles will to a greater extent than is the case for the large ones be deflected by the primary air which is injected via the outer annular primary air nozzle which is parallel to the main axis of the burner. Hence it will be possible to achieve a more uniform combustion of all particles, regardless of their size. It will be possible to change the path of the particles by altering the velocity or direction of injection.
Patent AU-2007327889-B2 (AU)
Title: Regulated gaming-compartmented freelance code
Inventor: BRUNET DE COURSSOU THIERRY
IPC: A63F13/00
Filed: 2007-08-08
Granted: 2013-06-20
Abstract: Compartmented system architecture and methods for enabling freelance game developers to (a) integrate their game software together with the slot manufacturer software and (b) tag their software such as to receive compensation based on the success of their games. The combined tagged freelance software and gaming manufacturer software may rapidly pass through certification testing and be downloaded overnight to a large number of gaming machines such as to offer players in casinos an unprecedented choice of new generation electronic games within a short timetable. Compartmenting for totally isolating the freelance graphics-rich game code from the slot supplier code may be carried by adopting the blue-screen paradigm in which the freelance code executes in a process sandbox and renders its entertainment outcome-free graphics in a totally isolated virtual background display plane while the slot supplier code renders its accounting graphics and outcome graphics in a virtual foreground display plane as small graphics gadgets animated over a transparent plane. The foreground and background display planes may then be mixed together and foreground moving outcome graphics gadgets may be synchronized in real-time with the moving outcome-free background graphics.
Patent AU-2008202655-B2 (AU)
Title: Methods and kit for maintaining a sterile environment during calibration of a medical device
Inventor: KRAUS ROBERT G
IPC: B65D25/54
Filed: 2008-06-16
Granted: 2013-06-27
Abstract: A method for maintaining a medical device in a sterile atmosphere at a desired temperature during a calibration step is provided. The method includes packaging a medical device and temperature indicator in a sterile container such that 5 the indicator is visible to a user. Next, heat can be applied to the container in order to stabilize the temperature of the container (as indicated by the encased temperature indicator) at room temperature. Once at room temperature, the device can be calibrated while remaining in the sterile atmosphere. A kit including such a container and a set of instructions is also provided. Like above, the container of the 10 kit can include a sterile medical device and temperature indicator such that the device can be maintained in a sterile environment during calibration and/or zeroing. As such, the method and kit allow for increased precision and safety in performing medical procedures. 16/06/08,kn 17326 specificaiont,18 14b 14a
Patent AU-2008212625-B2 (AU)
Title: 3-amino-pyrrolo[3,4-c] pyrazole- 5 (1H, 4H, 6H) carbaldehyde derivatives as PKC inhibitors
Inventor: YIN CHUNFENG
IPC: A61P3/00
Filed: 2008-02-04
Granted: 2012-07-19
Abstract: The present invention relates to compounds and pharmaceutically acceptable salts of Formulas A and B: (A) and (B) wherein A, B, R, R, R, R, R, R, R, R, R and R are as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically acceptable salts and to methods of treating diabetes mellitus and its complications, cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, Alzheimer's disease and dermatological disase pression, virus diseases, inflammatory disorders, or diseases in which the liver is a target organ.
Patent AU-2008235044-B2 (AU)
Title: Stable aqueous G-CSF formulations
Inventor: HEINRICH MATOUS
IPC: A61K9/12
Filed: 2008-04-04
Granted: 2011-08-25
Abstract: The invention relates to stable glutamate-buffered G-CSF formulations having a pH of from 3.5 to 4.8. The invention further concerns lyophilisates and powders obtainable from such formulations, and to pharmaceutical kits containing such lyophilisates and powders.
Patent AU-2008249022-B2 (AU)
Title: Method and apparatus for measuring a parameter within the well with a plug
Inventor: AUZERAIS FRANCOIS
IPC: E21B47/12
Filed: 2008-04-23
Granted: 2014-04-24
Abstract: The invention provides a system for measuring a parameter within a well, made of: a first apparatus comprising a first reel of first wound optic fiber line (or fiber) able to be unwound from the first reel, at least a first sensor able to measure the parameter of the well, wherein an information on said parameter can be transmitted trough the first optic fiber; a second apparatus comprising a second reel of second wound optic fiber line able to be unwound from the second reel, an extremity of the second optic fiber being fixed to a reference point; a light transmitter or receiver device linked to the reference point and able to generate or detect a light pulse through the second optic fiber line; and means to exchange said light pulse between first and second optic fiber line.
Patent AU-2008251324-B2 (AU)
Title: ((Phenyl)imidazolyl)methylheteroaryl compounds
Inventor: HEIDELBAUGH TODD M
IPC: A61P29/00
Filed: 2008-05-13
Granted: 2014-05-01
Abstract: Disclosed herein is a compound of the formula wherein A and B are described herein. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
Patent AU-2008306625-B2 (AU)
Title: Pyrazin-2-yl-pyridin-2-yl-amine and pyrazin-2-yl-pyrimidin-4-yl-amine compounds and their use
Inventor: SCANLON JANE ELIZABETH
IPC: A61P35/00
Filed: 2008-10-06
Granted: 2014-10-16
Abstract: The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain biarylamine compounds (referred to herein as BAA compounds), and especially certain pyrazin- 2 - yl -pyridin- 2 -yl -amine and pyrazine - 2 - yl -pyrimidin- 4 - yl -amine compounds of formula (I), which, inter alia, inhibit Checkpoint Kinase 1 (CHK1 ) kinase function The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit CHK1 kinase function, and in the treatment of diseases and conditions that are mediated by CHK1. that are ameliorated by the inhibition of CHK1 kinase function, etc., including proliferative conditions such as cancer, etc., optionally in combination with another agent, for example, (a) a DNA topoisomerase I or Il inhibitor; (b) a DNA damaging agent; (c) an antimetabolite or TS inhibitor; (d) a microtubule targeted agent; and (e) ionisiπq radiation. wherein: -X= is independently -CR