baber/WOPTO huggingface dataset:
Patent ME-01063-B (ME)
Title: Processes for preparing eptifibatide and pertinent intermediate compounds
Inventor: HO GUOJIE
IPC: C07K7/00
Filed: 2005-04-08
Abstract: The present invention provides, inter alia, convergent processes for preparing eptifibatide that involve coupling a 2-6 eptifibatide fragment to an activated cysteinamide residue to form a 2-7 eptifibatide fragment, attaching a mercaptopropionic acid residue to the 2-7 eptifibatide fragment through disulfide bond formation, coupling the peptide intramolecularly, and removing the protecting group, to form eptifibatide. The invention further provides products produced by the described processes, novel compounds that can be used as synthetic intermediates for the preparation of eptifibatide, and novel compounds that are structurally similar to eptifibatide.
Patent MX-168876-B (MX)
Title: Procedimiento para la preparacion de nuevas sales fisiologicamente activas o aceptables de sabor dulce
Inventor: COLL ALBERTO PALOMO
IPC: A23L27/00
Filed: 1986-09-19
Abstract: La presente invención se refiere a procedimiento para la preparación de nuevas sales fisiológicamente activas o aceptables de sabor dulce, caracterizado porque se hace reaccionar un edulcorante ácido con un edulcorante dipéptido derivado del ácido L-aspártico.
Patent MX-164595-B (MX)
Inventor: BENEDETTI GIAMPIETRO
IPC: C21C5/52
Filed: 1987-09-21
Abstract: Integrated plant (10) to convert a metallic charge continuously into semi-finished products such as billets, blooms, slabs, bars or ingots, which comprises in close cooperation a chamber (14) to pre-heat a controlled metallic charge, the chamber (14) including a burner (15) and a terminal feeder (16) feeding an electric furnace (17) with a controlled flow, and comprises also the electric furnace (17). a continuously functioning transformer (26), a multifunction manipulator (20) with two independent arms able to rotate circumferentially and to move vertically to handle two ladles (18) at one and the same time at least between a tapping station of the electric furnace (17) and a casting and tapping station (21), and at least one casting and tapping station (21) served by a tundish feeding liquid metal continuously, a station to refine the liquid metal in the ladle (18) being located between the tapping station of the furnace (17) and the tapping and casting station (21). Smelting method obtained with the plant (10) of the claims hereinbefore, which feeds molten metal coninuously at least to one casting station (21) by means of two ladles (18) feeding a tundish alternately and starts with a pre-set and variable metallic charge, such metallic charge being fed continuously in the opposite direction to heating means in a pre-heating chamber (14), such charge feeding continuously with an adjustable flow an electric furnace (17) whence liquid metal is tapped regularly and partially into ladles (18) able to move along a circumference, in which method the liquid metal is treated and refined in the ladle (18) before being delivered by one of the ladles (18) alternately into a tundish which transfers it continuously to the casting station (21) while the other ladle (18) is engaged in succession in operations of preparation, charging and refining, the cycle proceeding continuously without operating interference.
Patent MX-166186-B (MX)
Title: Metodo para crioperservar valvulas cardiacas
Inventor: BANK HARVEY L
IPC: A01N1/02
Filed: 1987-11-18
Abstract: La presente invención se refiere a un método de criopreservar válvulas cardiacas que comprende las etapas de: a. disecar de un corazón una válvula cardiaca, b. colocar la válvula cardiaca disecada en un medio isotónico con antibióticos y un criopreservativo, c. congelar la válvula cardiaca conforme a un programa de congelación que mantendrá niveles aceptables de viabilidad de las células y d. almacenar la válvula cardiaca a una temperatura inferior a los -132 grados C.
Patent NL-143144-B (NL)
IPC: B03D1/14
Filed: 1963-03-13
Abstract: 1,011,667. Froth-flotation cells. ELECTRO-PHYSIQUE S.A.R.L. March 14, 1963 [March 14, 1962], No, 10194/63. Heading B2H. A froth-flotation plant comprises a plurality of cells of which at least one is associated with a shoot for receiving unfloated matter, the shoot having two openings for the supply thereto or outflow therefrom of unfloated matter. As shown in Figs. 2, 3 and 5, a double series of shoots is provided between two rows of cells 1-6. The shoot adjacent the cell 1 has discharge openings 15, 73, either of which can be closed as shown in Figs. 2 and 6 depending on whether the cell is to be arranged in series or in parallel with the other cells. In Fig. 2, the products to be treated are fed into the cell 1 through an opening 16 and the floats discharged with the froth over the side opposite to that of the shoot while the unfloated products discharge to the next cell 2 via both a lower opening 18 and a recess 17 and then openings 15, 58; the opening 18 and recess 17 may be provided with adjustable doors. The unfloated products of the cell 2 are then discharged through both a lower opening 60 and a recess 59 and then through openings 29, 38 to the cell 3 ; the products then pass through the cells 4, 5 and 6 in a similar manner. In Fig. 6, the products are caused to pass from cell 1 to cell 3 by closing discharge opening 15 and discharge opening 73 so that the discharge through the openings 17, 18 is directed through an opening 38; the products then pass through the next cell 5 in a similar manner. In another arrangement, Fig. 7, the shoots between the cells, which are offset with one another, are provided with discharge openings a and b, either of which can be closed depending on whether it is desired to effect parallel flow through the cells as shown or otherwise. The cells may be arranged so that some operate in series and others in parallel by opening or closing the appropriate discharge opening in each shoot.
Patent NO-132747-B (NO)
Inventor: HARTMANN K O
IPC: A23B4/06
Filed: 1970-09-09
Abstract: Fremgangsmåte og apparat til formning av frosne enhetsporsjoner av fisk.
Patent NO-137558-B (NO)
Title: Fremgangsm}te for overflateliming av papir
Inventor: NAARMANN HERBERT
IPC: D21H17/43
Filed: 1972-12-12
Abstract: Fremgangsmåte for overflateliming av papir.
Patent NO-144467-B (NO)
Title: Anvendelse av en blanding som smakssettende middel for tilveiebringelse av kjoettsmak i et naeringsmiddel
Inventor: CORBETT CONSTANCE KATHLEEN
IPC: A23L27/21
Filed: 1977-06-07
Abstract: Anvendelse av en blanding som smakssettende middel for tilveiebringelse av kjøttsmak i et næringsmiddel.
Patent NO-149822-B (NO)
Title: Metallanode for elektrolyseceller med vandig elektrolytt og fremgangsmaate til fremstilling derav
Inventor: HAZELRIGG MARK JONATHAN JR
IPC: C25B11/10
Filed: 1977-06-30
Abstract: Metallanode for elektrolyseceller med vandig elektrolytt og fremgangsmåte til fremstilling derav.
Patent NO-165177-B (NO)
Inventor: NOSEWORTHY MELVIN MACKENZIE
IPC: C07D417/12
Filed: 1984-04-24
Abstract: A process has been developed for preparing the sodium, the monoethanolamine and the diethanolamine salts of piroxicam, in which the salt is deposited on a pharmaceutically-acceptable carrier. The compositions so obtained are useful for preparing pharmaceutical dosage forms of piroxicam, from which piroxicam is rapidly absorbed from the gastrointestinal tract after oral administration to mammals. These latter dosage forms are particularly suitable when it is desired to use piroxicam as an analgesic agent, where rapid onset of action is necessary.
Patent NO-174626-B (NO)
Inventor: BAILLY JEAN-CLAUDE ANDRE
IPC: C08F4/64
Filed: 1989-02-24
Abstract: A catalyst of the Ziegler-Natta type is prepared using a preactivated support containing (A) from 80 to 95 mol % of magnesium chloride and (B) 5 to 20 mol % of at least one electron donor compound which contains no labile hydrogen and no ester function; the preactivated support consisting of spherical particles having a mass average diameter, Dm of 10 to 100 microns and a particle size distribution Dm/Dn of less than 2. The catalyst is prepared by (i) treating the preactivated support with at least one electron donor compound containing labile hydrogen, (ii) optionally treating the resulting activated support with at least one ester of an aromatic acid, (iii) impregnating the treated support with titanium tetrachloride and (iv) after washing the impregnated catalyst activating it with titanium tetrachloride. The catalyst has a high titanium content and a high activity when used to polymerise olefins.
Patent NO-177694-B (NO)
Inventor: TRAEGAARDH PAUL
IPC: B31B50/76
Filed: 1989-08-22
Abstract: A method for raising flattened tubular blanks by rolling them out, or folding them by nearly 180 DEG  and reforming them to a square-shaped cross section uses the device comprising at least two discharging rollers (1, 1') for rolling out flattened tubular blanks (C) on a rolling line, and a pusher moving mechanism (4) for pushing the blanks (C) on said rolling line first into an overfolded position and thereafter, upon returning the pusher (2) to the original position, forming the square-shaped cross section of the blanks.
Patent NO-174275-B (NO)
Inventor: LAENN PER TERJE
IPC: A47B88/04
Filed: 1992-01-09
Abstract: PCT No. PCT/NO93/00003 Sec. 371 Date Sep. 27, 1994 Sec. 102(e) Date Sep. 27, 1994 PCT Filed Jan. 6, 1993 PCT Pub. No. WO93/13694 PCT Pub. Date Apr. 22, 1993.A wire drawer with a ribbon shaped upper rim. A guide roller is attached to the rim at each of two adjacent corners. To carry this roller, the rim is bent down at the corner to make a lug which is perpendicular to the plane of the rim. The axle of the roller is attached in a central area of this lug to hold the roller within the outer edge of the rim, but extending above its upper level.
Patent SE-305209-B (SE)
Inventor: GOTTFRIED S
IPC: C07C61/28
Filed: 1962-02-12
Abstract: The invention comprises glycyrrhetinic acid derivatives of the general formula <FORM:0887011/IV (b)/1> in which A and B and/or C and D can together represent a further bond and X is hydroxy, ethinyl or acyloxymethyl and in which rings Y and Z are cis- or trans-relationship, together with their preparation by brominating the corresponding 3,11-diketo-18a - or 18b -olean-12-ene 20-carboxylic acid to give the corresponding 2-bromo or 2,12,13-tribromo compound, dehydrobrominating to the corresponding 1,12-diene or 1,12,18-triene, and then, if desired, forming the acid chloride and converting it into the corresponding ethinylcarbonyl or acyloxyacetyl derivative.  The latter steps are carried out by treatment with thionyl chloride or oxalyl chloride to form the acid chloride, followed by reaction with sodium acetylide to form the ethinylcarbonyl derivatives, or with diazomethane followed by acid treatment of the resulting diazoketone to give the acyloxyacetyl derivative.  Detailed examples are given.  Specifications 798,655, 843,132, 843,133 and 843,137 are referred to.
Patent SE-333745-B (SE)
Inventor: HERMACH C
IPC: B41F27/12
Filed: 1967-03-21
Abstract: 1,148,014. Blanket-clamping device. MIEHLE - GOSS - DEXTER Inc. 27 Feb., 1967 [21 March, 1966], No. 9214/67. Heading B6C. An impression cylinder is provided with a clamping assembly having an elongated body fitted in a longitudinal groove of the cylinder, the sides of the body defining a longitudinal cavity with a narrow access slot and being undercut adjacent the slot to provide a pair of internal surfaces for seating the edges of a blanket; a pair of longitudinally extending leafsprings secured to the bottom of the cavity have blanket-engaging surfaces which are controlled by a further member container in the cavity Fig. 1 is a section of a clamping assembly 10 in which an impression cylinder 12 carried on a shaft 13 is recessed with a longitudinal groove 11; the cylinder is covered with a blanket 15 whose ends 16, 17 are securely gripped by the clamp assembly 10, which includes a cast block 20 having sides 21, 22 and a bottom 23 defining a central cavity 24 (Fig. 5a). The surface of the cylinder is continued by arcuate segments 25, 26 separated by an access slot 27, and the block 20 is formed with cap screws 30 for securing to the groove 11. The sides of block 20 are undercut adjacent slot 27 to form two longitudinallyextending surfaces 35, 36 which co-operate with a leaf-spring 40 having bowed sides 41, 42, a central base 43 and blanket-gripping surfaces 45, 46 with preferably triangular projections (47) (Fig. 6, not shown) and secured to the root of cavity 24 by screws, 52. A cam-shaft 60 having cam surfaces 61, 62 extends centrally through the springs 40 over the whole length of the cylinder and can be rocked by engagement of the faceted end (76) with a wrench and can be locked in any position by means of a spring plate (77) (Fig. 2, not shown). In operation, the cam-shaft 60 is rocked from a clamping position to a position in which one set of spring elements, e.g. 42 in Fig. 5a, are retracted from surface 36 allowing a blanket to be tucked therebetween; rotation of the cam-shaft 60 through about 130 degrees then forces spring 42 on to surface 36 engaging blanket end 16, and releases spring 41 from surface 35 allowing the other blanket end 15 to be tucked in; further rotation to a central reference position (Figs. 5b, 5c, not shown) clamps both blanket ends by means of engagement between surfaces 36, 46 and 35, 45. A modification (Fig. 9, not shown) involves auxiliary springs interposed between the cam and the clamp spring for further tensioning the latter.
Patent RS-51495-B (RS)
Inventor: RATCLIFFE ANDREW JAMES
IPC: C07D/
Filed: 2002-09-17
Abstract: Jedinjenja opšte formule (I):po izboru supstituisana na zasićenom prstenu sa jednim ili više alkil supstituenata, naznačena time, što:R1     predstavlja vodonik, R4, -C(=Y)-NHR4, -SO2NHR4, -C(=Z1)-R4, -SO2-R4 ili -C(=Z1)-OR4;R2     predstavlja vodonik, cijano, halogen ili -C≡C-R5;R3     predstavlja vodonik, acil, alkoksikarbonil, alkil, aroil, aril, ariloksikarbonil, karboksi, cikloalkenil, cikloalkil, heteroaroil, heteroaril, heterocikloalkil ili -C(=O)-NY1Y2;R4     predstavlja alkil, cikloalkil, cikloalkenil ili hetrocikloalkil, svaki po izboru supstituisan jednom ili više grupa odabranih od: aril, cikloalkenil, cikloalkil, heteroaril, heterocikloalkil, -C(=O)-OR8,-C(=O)-R9, -C(=O)-NY3Y4, -NY1Y2, -N(R10)-C(=O)-R9, -N(R10)-C(=O)-OR9, -N(R10)-SO2-R9 ili Z2R8; ili R4     predstavlja aril ili heteroaril, po izboru supstituisan jednom ili više grupa odabranih od alkilendioksi, alkenil, alkeniloksi, alkinil, aril, cijano, halo, hidroksi, heteroaril, heterocikloalkil, nitro, R7, -C(=O)-NY3Y4, -C(=O)-OR8, -C(=O)-R11, -NY3Y4, -N(R10)-C(=O)-R9, -N(R10)-C(=O)-NY5Y6, -N(R10)-C(=O)-OR9, -N(R10)-SO2-R9, -N(R10)-SO2-NY5Y6, -SO2-NY3Y4 i -Z2R12; R5     predstavlja vodonik ili alkil;R6 predstavlja alkil, acil, alkoksikarbonil, alkilsulfonil, aril, arilsulfonil, aroil, cikloalkil, cikloalkenil, heteroaril, heteroarilsulfonil, heteroaroil i heterocikloalkil;R7 predstavlja alkil, cikloalkil ili cikloalkilalkil, svaki po izboru supstituisan jednim ili više supstituenata odabranih od aril, cikloalkil, cijano, halo, heteroaril, heterocikloalkil, hidroksi, -CHO (ili njegov derivat 5-, 6- ili 7-članog cikličnog acetala), -C(=O)-NY1Y2, -C(=O)-OR8, -NY3Y4, -N(R10)-C(=O)-R9, -N(R10)-C(=O)-NY3Y4, -N(R10)-SO2-R9, -N(R10)-SO2NY3Y4 i -OR9;R8     predstavlja vodonik, alkil, alkenil, aril, arilalkil, heteroaril ili heteroarilalkil; R9     predstavlja alkil, aril, arilalkil, cikloalkil, cikloalkilalkii, heteroaril, hateroarialkil, heterocikloalkil ili heterocikloalkilalkil; R10    predstavlja vodonik ili niži alkil;R11 predstavlja alkil, aril, arilalkil, cikloalkil, cikloalkilalkil, heteroaril, heteroarilalkil, heterocikloalkil ili heterocikloalkilalkil; ili alkil, po izboru supstituisan sa -NY1Y2;R12 predstavlja aril ili heteroaril; ili alkil, cikloalkil, cikloalkilalkil, heterocikloalkil ili heterocikloalkilalkil, svaki po izboru supstituisan jednim ili više supstituenata odabranih od aril, cikloalkil, cijano, halo, heteroaril, heterocikloalkil, hidroksi, -CHO (ili njegov derivat 5-, 6- ili 7-članog cikličnog acetala), -C(=O)-NY1Y2, -C(=O)-OR8, -NY1Y2, -N(R10)-C(=O)-R9, -N(R10)-C(=O)-NY3Y4, -N(R10)-SO2-R9, -N(R10)-SO2-NY3Y4 i -OR9; Y predstavlja O, S ili NCN;Y1 i Y2 su nezavisno, vodonik, alkil, aril, cikloalkil, cikloalkenil, heteroaril ili heterocikloalkil; ili -NY1Y2 grupa može da formira 5- do 7-člani prsten koji po izboru sadrži dodatni heteroatom, o
Patent ZA-824603-B (ZA)
Title: Pharmaceutical carrier and compositions
Inventor: HIRSBRUNNER P
IPC: A61K9/14
Filed: 1982-06-28
Abstract: A pharmaceutical carrier or excipient comprises milk solids and tripotassium phosphate. It is especially suitable for preparing compositions containing moisture-sensitive active ingredients, which may also be acidic in character. The carrier is especially suitable for compounding with ASA (acetylsalicylic acid) to give compositions which disperse readily on contact with water. The resulting solutions are buffered and contain neutralized ASA dissolved in a liquid milk phase.
Patent ZA-829093-B (ZA)
Title: Microorganisms of the genus hyphomicrobium and process for degrading compounds which contain methyl groups in aqueous solutions
Inventor: GHISALBA ORESTE
IPC: C12N1/20
Filed: 1982-12-10
Abstract: The present invention relates to novel facultative methylotrophic microorganisms of the genus Hyphomicrobium, to protein-containing biomass, and to a process for the microbiological purification of aqueous solutions, e.g. wastewaters, which contain methanol, ethanol, glucose, dimethyl phosphite, trimethyl phosphite, sodium formate, sodium acetate, methylammonium chloride, dimethylammonium chloride, ethylmethylammonium chloride or, chiefly, sodium methyl sulfate, as pollutants. The respective microorganism is cultured in aqueous solution and the pollutant is degraded simultaneously.
Patent ZA-836395-B (ZA)
Title: Arachidonic acid analogues as anti-inflammatory and anti-allergic agents
Inventor: NELSON PETER HAROLD
IPC: C07C49/00
Filed: 1983-08-29
Abstract: Novel compounds of this invention are tetrazole, acylhydroxylamine, hydroxymethylketone and amide derivatives of unsaturated fatty acids which are selective inhibitors of the enzymes lipoxygenase and cyclooxygenase involved in the production of pain, inflammation, bronchoconstriction and allergic reactions. These compounds are beneficial in the treatment of a number of inflammatory and/or painful conditions and allergic reactions.
Patent ZA-847542-B (ZA)
Title: Polyester antifume additive for spandex fiber
Inventor: KETTERER CHARLES CLIFFORD
IPC: D01F1/10
Filed: 1984-09-25
Abstract: Saturated aliphatic polyesters having a repeating unit which has the structural form of a residue of a glycol combined with a residue of a diacid or the form of a residue of a hydroxy acid, the number of carbon atoms in the shortest chain between ends of the residues being in the range of 3 to 10 for the glycol residue and no more than 12 for the diacid residue or for the hydroxy acid residue, provide polyether-based spandex fibers with improved resistance to discoloration induced by exposure to nitrogen dioxide fumes.
Patent ZA-853132-B (ZA)
Title: Curable compositions
Inventor: IRVING EDWARD
IPC: C08G59/62
Filed: 1985-04-26
Abstract: Curable compositions, especially suitable for use as adhesives, contain (A) an anaerobically polymerizable mixture which is stable in oxygen but polymerizes when oxygen is excluded, comprising (i) a free radical polymerizable compound, such as an acrylate or methacrylate ester, (ii) an organic free radical initiator, such as a peroxide or hydroperoxide, and (iii) an organic accelerator of free radical polymerization (B) an epoxide resin, and (C) a curing agent for epoxide resins that is a basic curing agent, a polymercaptan, or a polyhydric phenol. These compositions cure rapidly by an araerobic curing mechanism and then develop high strength by cure of the epoxide resin.
Patent ZA-862233-B (ZA)
Title: Tungsten recovery
Inventor: ANDERSON DIANA MARY
IPC: C22B7/00
Filed: 1986-03-25
Abstract: The scarcity of high grade tungsten ores obliges users to seek to recover it from scrap materials, but drill bits in particular pose special problems. Existing proposals to use acidic hydrogen peroxide to oxidize and solubilize tungsten are extremely inefficient in reagent consumption per unit tungsten recovered. According to the present invention hydrogen peroxide can be used considerably more efficiently with sub-stoichiometric reagent addition per stage, especially from 6 to 12 stages and by the use of a small amount of certain promoters which it is believed may form a water-soluble complex with tungsten which provides an alternative route for tungsten dissolution. Many of the promoters are aromatic hydroxyl or amino acids such as 2-hydroxybenzoic acid, 2-aminobenzoic acid, 4-hydroxybenzene-phenol and its related oxidation products such as 1,4-benzoquinone. Also, certain aliphatic acids such as tartaric and epoxy succinic acid show some promotional activity.
Patent ZA-864407-B (ZA)
Title: Closure construction having back-up support means
Inventor: BAUGHMAN GARY M
IPC: B21D51/40
Filed: 1986-06-12
Abstract: A closure (20) and boss (41) combination for providing an internally threaded outlet (21) in a drum end includes a raised metal boss (41) formed in the drum end and configured with a pair of concentric axially extending annular walls (43, 44) connected by an annular ring-shaped top surface. Securely crimped within the raised metal boss is a synthetic material closure (20) which includes an internal series of threads (23) surrounded by a crimping flange (24) which includes on its outer diameter surface a series of serrations configured with alternating recesses (26) and protruding portions (27). The flange includes an interior support surface (30) which is substantially concentric with the outer surface of the serrations and the inner, axially extending wall portion (44) of the boss is contiguous with this inner support surface in order to provide back-up support and preclude close-in of the closure and distortion of the closure threads during the crimping operation and during subsequent stress-inducing operations such as exposure to high-temperature sources.
Patent ZA-872925-B (ZA)
Title: Heterocyclic compounds
Inventor: COATES WILLIAM JOHN
IPC: C07C333/04
Filed: 1987-04-24
Abstract: Compounds of the formula (I) : <CHEM> and pharmaceutically acceptable salts thereof are described, wherein R<1> is hydrogen or methyl, and n is one, and when R<1> is hydrogen n can also be two. These compounds have inotropic, vasodilator, broncho-dilating and platelet aggregation inhibiting properties. pharmaceutical compositions are described as are methods of use. Intermediates and processes for the preparation of the compounds of the formula (1) are described.
Patent ZA-874123-B (ZA)
Title: Variants of alpha1-antitrypsin which are useful,in particular,as kallikrein inhibitors
IPC: C12N15/09
Filed: 1987-06-09
Abstract: The invention relates to the variant of human alpha1-antitrypsin of formula: (Ala357, Arg358) alpha1-AT. This compound is useful as a kallikrein inhibitor.
Patent ZA-896688-B (ZA)
Title: Wedge-shaped port for flexible containers
Inventor: MILLER ROBERT A
IPC: A61J1/00
Filed: 1989-08-31
Abstract: A wedge-shaped access port (18) for a flexible container (10) which is formed of at least one or more sheets of material (12) which are sealed together about the edges (14) to form a cavity (16). The wedge-shaped port (18) is sealed to the container (10) so that a base (22) of the wedge is exterior to the cavity (16) and a thin edge of the wedge is located inside the cavity (16). An orifice (20) in the port (18) provides a passageway from the base (22) of the wedge to the cavity (16). The wedge shape of the port (18) allows sealing of the port (18) to container (10) with minimal stress or thinning of material at the seal between the port (18) and the container (10).