baber/WOPTO huggingface dataset:
Patent EP-3544016-A2 (EP)
Title: Methods for combining predicted and observed mass spectral fragmentation data
Inventor: TAUTENHAHN RALF
IPC: G16C20/20
Filed: 2019-03-19
Abstract: A method for generating a searchable small-molecule tandem mass spectrometry library comprises: (a) generating, by theoretical calculation and for each of a plurality of small-molecule compounds, a list of ion species, including fragment-ion species that are predicted, by the theoretical calculations, to be generated by tandem mass spectrometry (MS n ) analyses, where  n  ≥ 2; (b) comparing at least a subset of the predicted ion species to entries in a database that includes a list of experimentally observed ion species; (c) matching a predicted mass-to-charge ratio (m/z) value of each of one or more of the predicted fragment-ion species to a respective experimentally measured  m / z  value of an experimentally observed fragment-ion species for which information is tabulated in the database; and (d) updating the predicted list of ion species based on information derived from the matched predicted and experimentally measured  m / z  values.
Patent EP-3599597-A2 (EP)
Title: Verfahren zur steuerung des betriebs eines vollautomatischen, zur unabhängigen fahrzeugführung ausgebildeten fahrerassistenzsystems eines kraftfahrzeugs und kraftfahrzeug
Inventor: HÖRWICK MARKUS
IPC: B60W30/095
Filed: 2011-05-23
Abstract: Verfahren zur Steuerung des Betriebs eines vollautomatischen, zur unabhängigen Fahrzeugführung ausgebildeten Fahrerassistenzsystems eines Kraftfahrzeugs, wobei ein Plausibilitätsüberwachungsmodul unter insbesondere ausschließlicher Berücksichtigung von von wenigstens einem Sensor und/oder Fahrzeugsystem ermittelten, den aktuellen Betriebszustand des Kraftfahrzeugs beschreibenden Egodaten und Umfelddaten, insbesondere von den auch zur Ermittlung der Fahrzeugsführungsaktionen des Fahrerassistenzsystems verwendeten Eingangsdaten, überprüft, ob wenigstens ein im Hinblick auf die Funktion des Fahrerassistenzsystems ausgeschlossener Fehlerfall vorliegt, wobei bei Vorliegen eines Fehlerfalls ein wenigstens einen zur Überführung des Kraftfahrzeugs in einen sicheren Zustand, insbesondere den Stillstand, dienenden Fahreingriff umfassender Aktionsplan, der einen zeitlichen Ablauf von Steuerungsbefehlen für Fahrzeugsysteme enthält, ausgeführt wird.
Patent EP-3683312-A2 (EP)
Inventor: BARELLE CAROLINE JANE
IPC: C12N15/13
Filed: 2014-04-23
Abstract: The present invention provides methods for the production of a library of antigen specific antigen binding molecules having a peptide domain structure represented by the following formula (I):         FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4comprising (1) isolating RNA from a member of a species in the Elasmobranchii subclass; (2) amplifying DNA sequences from RNA obtained; (3) selecting a DNA sequence from the database prepared; (4) amplifying DNA sequences encoding two or more contiguous peptide domains of FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4; (5) ligating together said amplified DNA sequences to form DNA sequences encoding an antigen specific binding molecule; (6) cloning the amplified DNA obtained into a display vector; and (7) transforming a host with said display vector to produce a library of said antigen specific antigen binding molecules. The invention also provides methods for the production of an antigen specific antigen binding molecule as defined, pharmaceutical compositions comprising such molecules and uses thereof in medicine.
Patent EP-3868128-A2 (EP)
Inventor: WEXLER YONATAN
IPC: G06F3/01
Filed: 2019-10-10
Abstract: A hearing aid and related systems and methods. In one implementation, a hearing aid system may selectively amplify sounds emanating from a detected look direction of a user of the hearing aid system. The system may include a wearable camera configured to capture a plurality of images from an environment of the user; at least one microphone configured to capture sounds from an environment of the user; and at least one processor programmed to receive the plurality of images captured by the camera, receive audio signals representative of sounds received by the at least one microphone from the environment of the user, determine a look direction for the user based on analysis of at least one of the plurality of images, cause selective conditioning of at least one audio signal received by the at least one microphone from a region associated with the look direction of the user, and cause transmission of the at least one conditioned audio signal to a hearing interface device configured to provide sound to an ear of the user.
Patent EP-3884041-A2 (EP)
Inventor: BIGLEY AUSTIN
IPC: A61K35/17
Filed: 2019-11-21
Abstract: Provided herein are methods for ex vivo expansion of a specialized subset of natural killer (NK) cells, and compositions containing such NK cells. Also provided are methods for identifying or detecting a specialized subset of NK cells. Also provided are methods for treating diseases and conditions such as cancer using provided compositions, including in combination with an antibody capable of binding to disease-associated tissues or cells, such as tumor cells or infected cells.
Patent EP-3751603-A2 (EP)
Inventor: HSIEH YA-JUI
IPC: H01L23/31
Filed: 2020-06-10
Abstract: A semiconductor package structure (200, 300, 400) includes a substrate (102), a semiconductor die (106), a molding material (108), a first bonding layer (126), and a thermal interface material (120). The semiconductor die (106) is disposed over the substrate (102). The molding material (108) surrounds the semiconductor die (106). The first bonding layer (126) is disposed over the semiconductor die (106). The thermal interface material (120) is disposed over the molding material (108). The semiconductor package structure (200, 300, 400) may further comprise a heatsink (122) disposed over the bonding layer (126), wherein the thermal interface material (120) may connect the molding material (108) and the heatsink (122). The inclusion of both of thermal interface material (120) and the bonding layer (126) improves the heat dissipation efficiency without increasing stress, which is preferred for high-power applications, resulting at the same time in enhancement of thermal performance, manufacturability and reliability. The thermal interface material (120) may be adhesive. The thermal interface material (120) may surround the first bonding layer (126). A metal layer (124) may be disposed between the first bonding layer (126) and the semiconductor die (106). The thermal interface material (120) may partially surround the metal layer (124) and the bonding layer (126). The thermal interface material (120) may be spaced apart from the metal layer (124) and the bonding layer (126) by a gap, to prevent the issues caused by different coefficients of thermal expansion (CTE) of the thermal interface material (120), the metal layer (124) and the bonding layer (126). The thermal interface material (120) may be thicker than the metal layer (124) and thicker than the bonding layer (126). The thermal interface material (120) may have a notch and/or may be cut off by a gap (132) or by a plurality of gaps, to release gas generated during the manufacturing process. The semiconductor package structure (200, 300, 400) may further comprise a conductive element (104) (e.g., conductive ball structures, conductive pillar structures or conductive paste structures) disposed between the semiconductor die (106) and the substrate (102). The semiconductor package structure (400) may further comprise another heatsink (130) disposed below the substrate (102) and bonded onto the substrate (102) through a second bonding layer (128), wherein the first bonding layer (126) has a melting point lower than the second bonding layer (128). The first bonding layer (126) may comprise SnBi, SnBiAg, or a combination thereof. A sidewall of the thermal interface material (120) may be aligned with a sidewall of the molding layer (108) or inside it. The upper surface of the semiconductor die (106) may be covered or exposed by the molding material (108).
Patent EP-3816307-A2 (EP)
Title: Method for production of flat steel plates
Inventor: SAEY BERNARD
IPC: C21D9/46
Filed: 2020-10-26
Abstract: In a first aspect, the invention provides a method for the production of flat steel sheets, comprising the uncoiling of a coil of steel material, the flattening of the uncoiled steel material, the stretching of a segment of the steel material and the transverse cutting of said segment. In particular, a steel material is used with a silicon content of at most 0.60 %, preferably at most 0.50 %, a yield strength of minimum 235 N/mm2 and a tensile strength of minimum 340 N/mm2 . In a further aspect, the invention also provides a flat steel sheet, preferably obtained by applying the method.
Patent EP-3859725-A2 (EP)
Title: Display device
Inventor: OCK JONG-HWAN
IPC: G09G3/3233
Filed: 2020-12-30
Abstract: The present disclosure relates to a display device capable of improving definition deterioration due to recognition of a boundary of a low-resolution area superposed on an optical module in a display area and enhancing the definition of the low-resolution area to a recognition level equivalent to that of a high-resolution area, and a display device according to an embodiment includes: a panel including a display area in which a plurality of pixels is arranged; and an optical module superposed on the display area, wherein the display area has a low-resolution area having a polygonal shape and superposed on the optical module and a high-resolution area neighboring the low-resolution area, unit pixels having the same size as those of the high-resolution area are arranged in a lower pixel density than that of the high-resolution area and transmission areas are disposed adjacent to the unit pixels in the low-resolution area, and unit pixels and transmission areas are arranged in different forms in a boundary area of the high-resolution area neighboring the low-resolution area according to slopes of the boundary area.
Patent EP-3917952-A2 (EP)
Inventor: ZHANG SHAOFEI
IPC: C07K14/705
Filed: 2020-01-21
Abstract: Antibodies having binding specificity to CD44 v7/8, ( a.k.a.  CD44 variant 7/8) and antibody-drug conjugates (ADCs) or chimeric antigen receptors comprising such. Also provided herein are uses the anti-CD44 v7/8 antibodies, the ADCs, or immune cells expressing the chimeric antigen receptors for therapeutic and diagnostic purposes.
Patent EP-4079683-A2 (EP)
Title: Method for controlling particle sizes of lithium peroxide and method for preparing particle size-controlled lithium oxide
Inventor: LEE JAE MYUNG
IPC: C01B15/043
Filed: 2020-12-07
Abstract: The present invention relates to a novel method for preparing lithium oxide. In the present invention, the particle size and shape of lithium oxide may be controlled during the preparing process. In addition, the present invention relates to lithium oxide with controlled particle size and shape prepared by this preparing method.
Patent EP-3939446-A2 (EP)
Inventor: BLANDINO THOMAS P
IPC: A24F40/20
Filed: 2016-08-26
Abstract: Disclosed is apparatus (100, 200, 300) for heating smokable material to volatilise at least one component of the smokable material. The apparatus (100, 200, 300) comprises a heating zone (113) for receiving at least a portion of an article comprising smokable material; a magnetic field generator (120) for generating a varying magnetic field; and an elongate heating element (110) extending at least partially around the heating zone (113) and comprising heating material that is heatable by penetration with the varying magnetic field to heat the heating zone (113).
Patent EP-3910237-A2 (EP)
Title: Brenneranordnung und verteilblech
Inventor: POLUS MARKUS
IPC: F23D14/14
Filed: 2021-05-07
Abstract: Die Erfindung betrifft eine Brenneranordnung mit einem Brennerkörper (3), der eine Innenoberfläche (4) und eine Außenoberfläche (5) sowie ein Muster aus Öffnungen (6) zum Durchtritt eines Luft-Brenngas-Gemisches aufweist, und einer lonisationselektrode (7) mit einer Elektrodenlänge (EL), die mit einem Abstand (A) von der Außenoberfläche (5) des Brennerkörpers (3) und im Wesentlichen parallel zu dieser verläuft, wobei ein Verteilbleich (8) vorhanden ist, welches das Muster aus Öffnungen (6) im Bereich (10) der lonisationselektrode (7) verändert, indem es einen Teil der Öffnungen (6) zumindest teilweise abdeckt. Die Erfindung erlaubt es, mit einfachen Mitteln die Anwendbarkeit und/oder Genauigkeit eines lonisationsmesssystems zu erweitern und damit ausgestattete Heizgeräte in einem breiten Leistungsbereich zu regeln.
Patent EP-4080511-A2 (EP)
Inventor: Lu chao-chun
IPC: G11C11/4074
Filed: 2022-01-26
Abstract: The invention relates to DRAM with sustainable storage architecture. The DRAM comprises a DRAM cell with an access transistor and a storage capacitor, and a word-line coupled to a gate terminal of the access transistor. During the period between the word-line being selected to turn on the access transistor and the word line being unselected to turn off the access transistor, either a first voltage level or a second voltage level is stored in the DRAM cell, wherein the first voltage level is higher than a voltage level of a signal ONE utilized in the DRAM, and the second voltage level is lower than a voltage level of a signal ZERO utilized in the DRAM.
Patent EP-4039520-A2 (EP)
Inventor: AHN SUNG JOON
IPC: B60K35/00
Filed: 2022-02-09
Abstract: A vehicle display device according to an embodiment of the disclosure includes a display that displays, as an image, functions for various pieces of vehicle operation information, a knob that is electrically interlocked with the display and selectively operates a corresponding function of the display according to left-right movement thereof, a guide rail that provides a movement path of the knob and divides a plurality of functional areas interlocked with the functions displayed on the display, and a guide part in which magnets having different polarities are alternately arranged in a lengthwise direction of the guide rail to automatically guide a location of the knob.
Patent EP-4042990-A2 (EP)
Inventor: ROSS MARK W
IPC: A61F9/008
Filed: 2015-12-16
Abstract: Eliminating leaks of molded fluid channels by providing a front housing, rear housing, and a gasket, wherein the front housing has one or more molded fluid channels and one or more seal channels, and wherein at least a portion of the gasket is located between the front and rear housing; molding the gasket onto the rear housing to create a single unit, wherein the gasket has one or more seal lips configured and dimensioned to couple with the one or more seal channels; and assembling the front housing to the rear housing having the gasket, wherein the one or more seal lips couple with the seal channels. A surgical cassette manifold having a front and rear housing, and a gasket therebetween. The front housing having molded fluid channels that mate with the gasket and the gasket having multiple valves and a sensor/ diaphragm accessible through the rear housing.
Patent EP-4089240-A2 (EP)
Inventor: SPÖLER THOMAS
IPC: E03B7/08
Filed: 2022-05-06
Abstract: Die vorliegende Erfindung betrifft ein Toilettenspülmodul mit einem Spülkasten (4) zum Vorhalten eines Spülvolumens (6), von dem eine Spülleitung (12) abgeht, die den Spülkasten (4) mit einem Anschluss für eine Toilettenschüssel (48) verbindet, einem Einlassventil (28) zum Befüllen des Spülkastens (4), das an eine Frischwasserleitung (26) anschließbar ist, und einem Abwasserrohr (14), über das die Toilettenschüssel (48) mit einer Abwasserleitung (50) verbindbar ist. Das Toilettenspülmodul zeichnet sich durch eine parallel zu der Spülleitung (12) geschaltete Bypassleitung (16) aus, über die der Spülkasten (4) unter Umgehung der Toilettenschüssel (48) mit der Abwasserleitung (50) verbindbar ist. In einem nebengeordneten Aspekt betrifft die vorliegende Erfindung eine Toilette und in einem anderen nebengeordneten Aspekt ein Spülmodul zur Umgehung eines an eine Trink- und Brauchwasserinstallation angeschlossenen Einrichtungsgegenstands.
Patent EP-4119577-A2 (EP)
Inventor: SCHWAEBLE HANS-WILHELM
IPC: C07K16/40
Filed: 2013-06-18
Abstract: In one aspect, the invention provides methods and compositions for inhibiting MASP-3-dependent complement activation in a subject suffering from or at risk for developing, a disease or disorder selected from the group consisting of paroxysmal nocturnal hemoglobinuria, age-related macular degeneration, arthritis, disseminated intravascular coagulation, thrombotic microangiopathy, asthma, dense deposit disease, pauci-immune necrotizing crescentic glomerulonephritis, traumatic brain injury, aspiration pneumonia, endophthalmitis, neuromyelitis optica and Behcet's disease by administering to the subject a composition comprising an amount of a MASP-3 inhibitory agent in an amount effective to inhibit MASP-3-dependent complement activation. In some embodiments, the subject is administered a MASP-2 inhibitory agent and a MASP-1 inhibitory agent, a MASP-2 inhibitory agent and a MASP-3 inhibitory agent administered, a MASP-3 inhibitory agent and a MASP-1 inhibitory agent, or a MASP-1 inhibitory agent, a MASP-2 inhibitory agent and a MASP-3 inhibitory agent.
Patent EP-4155674-A2 (EP)
Inventor: MARSH BRIAN JOHN
IPC: G01S19/49
Filed: 2022-08-08
Abstract: Method, apparatuses, and computer program products for automatically tracking a heading of an object. An example method comprising receiving, one or more internal measurement values which pertain to an object; determining an internal heading uncertainty value for each internal measurement value of the one or more internal measurement values; generating, using a probabilistic heading model, an estimated heading data object for the object based at least in part on the one or more internal measurement values; and providing the estimated heading data object to one or more associated user devices.
Patent EP-4159453-A2 (EP)
Inventor: RILEY TERRELL DIANE
IPC: B05B13/00
Filed: 2022-09-02
Abstract: Systems, apparatuses and methods provides for technology that applies, with a printhead (124) of a printing system (100), ink (234, 236) to a substrate (170) as the substrate (170) remains stationary and the printhead (124) moves across the substrate (170). The technology determines, with a distance encoder (114), a distance that the printhead (124) has moved, and controls application of the ink (234, 236) from the printhead (124) to the substrate (170) based on the distance.
Patent EP-4095449-A2 (EP)
Inventor: PLASSER MARKUS
IPC: F24F140/12
Filed: 2022-10-07
Abstract: A method of controlling an HVAC system 1 comprising a fluid transportation network (100) having network section(s) (F, F a-z ), each being connected to a fluid transportation circuit (C, C a-z ) through respective supply line(s) (LS, LS a-z ) and return line(s) (LR, LR a-z ), each network section (F, F a-z ) comprising a plurality of parallel zones (Z 1-n , Z a-z.1-n ), the method comprising: arranging a pressure regulating device (PR, PR a-z ) in the supply line(s) (LS, LS a-z ) and/or respective return line(s) (LR, LR a-z ) of the network section(s) (F, F a-z ); arranging flow regulating devices (PI 1-n , PI a-z1-n ) in the zones (Z 1-n , Z a-z.1-n ) of the network sections (F a-z ); measuring a remote differential pressure dp Rem , dp Rem, a-z  of the fluid in a first zone (Z maxRes , Z maxRes ,  a-z ) of the plurality of zones (Z 1-n , Z a-z.1-n ) of each of the network sections (F, F a-z ); and controlling, by a controller (20), the pressure regulating device(s) (PR, PR a-z ) of each network section (F, F a-z ) to maintain the measured remote differential pressure dp Rem , dp Rem, a-z  within a specified differential pressure range
Patent EP-4215368-A2 (EP)
Inventor: WILLUTZKI SVEN THOMAS
IPC: B41F31/02
Filed: 2022-12-22
Abstract: Die vorliegende Erfindung betrifft ein Dichtungselement zur stirnseitigen Abdichtung einer Rakelkammer, gegenüber einer rotierenden Rasterwalze, mit einem Dichtungskörper (1) der an seiner Oberseite eine Dichtungsfläche (2) aufweist. In dem Dichtungskörper (1) ist ein in der Längsrichtung verlaufender und zur Verdichtungsfläche hin offener, insbesondere gradliniger Kanal (3) ausgebildet, welcher die Dichtungsfläche zumindest im Bereich des zentralen Dichtungsflächenabschnitts segmentiert, wobei in dem Dichtungskörper (1) zwei in der Längsrichtung verlaufende und zur Dichtungsfläche offene, insbesondere geradlinige Kanäle (3) ausgebildet sind, welche die Dichtungsfläche (2) zumindest im Bereich des zentralen Dichtungsflächenabschnitts (2a) unter Bildung eines zwischen den Kanälen (4) gelegenen mittleren Dichtungsstegs (4) und zwei äußeren Dichtungsstegen (5, 6) segmentieren, wobei der mittlere Dichtungssteg (4) in der Querrichtung des Dichtungskörpers (1) betrachtet mittig entlang der Längsrichtung verläuft.
Patent EP-4290542-A2 (EP)
Title: Thin layer metal oxide capacitor, electronic device including the same (dram), and method of preparing the same
Inventor: KIM JINHONG
IPC: H01G4/10
Filed: 2023-04-05
Abstract: A thin film capacitor (29) including a first thin-film electrode layer (11), a second thin-film electrode layer (13), a dielectric layer (12) between the first and second thin-film electrode layers, and a first interlayer between the first thin-film electrode layer and the dielectric layer and/or between the second thin-film electrode layer and the dielectric layer may be provided. The first interlayer includes a first metal oxide, the first and second thin-film electrode layers (11, 13) includes second metal having a conductive rutile (MO 2 ) crystal structure The dielectric layer (12) includes a third metal oxide having a dielectric rutile crystal structure, and the first metal oxide, the second metal oxide, and third metal oxide have different compositions from each other. The first metal oxide includes GeO 2 , the third metal oxide includes TiO 2 , and a thickness of the first interlayer is smaller than that of the dielectric layer. A DRAM comprising the capacitor.
Patent EP-4239080-A2 (EP)
Title: Method for analysis of an rna molecule
Inventor: WOCHNER ANIELA
IPC: C12Q1/6806
Filed: 2016-07-01
Abstract: The present invention relates to the field of RNA analysis. In particular, the invention concerns the use of a catalytic nucleic acid molecule for the analysis of an RNA molecule and/or of a population of RNA molecules. In one aspect, the invention concerns methods for analyzing RNA molecules having at least one cleavage site for at least one catalytic nucleic acid molecule. In particular, the invention concerns a method for determining a physical property of an RNA molecule by analyzing a 5' terminal fragment, a 3' terminal fragment and/or at least one optional central RNA fragment obtained by cleavage of the RNA molecule by at least one catalytic nucleic acid molecule. Moreover, the present invention provides novel uses of a catalytic nucleic acid molecule for analyzing RNA molecules. In particular, the invention relates to the use of a catalytic nucleic acid molecule in a method for analyzing RNA molecules, wherein the resulting 5' terminal RNA fragment, the 3' terminal RNA fragment and/or the at least one optional central RNA fragment are analyzed.
Patent EP-4242364-A2 (EP)
Inventor: IACIOFANO NICK
IPC: D03D15/56
Filed: 2018-07-30
Abstract: Cette couche (4) pour la construction d'un tuyau d'arrosage (H) s'étend autour d'un axe longitudinal (X). Cette couche présente des capacités d'allongement plus importantes dans une direction que dans l'autre par rapport à l'axe longitudinal (X).