baber/WOPTO huggingface dataset:
Patent IL-159671-A0 (IL)
Title: New assays for preimplantation factor and preimplantation factor peptides
IPC: C07K7/06
Filed: 2002-06-28
Abstract: The present invention relates to assay methods used for detecting the presence of PIF, and to PIF peptides identified using this assay. In particular, the present invention relates to flow cytometry assays for detecting PIF. It is based, at least in part, on the observation that flow cytometry using fluorescently labeled anti-lymphocyte and anti-platelet antibodies demonstrated an increase in rosette formation in the presence of PIF. It is further based on the observation that flow cytometry demonstrated that monoclonal antibody binding to CD2 decreased in the presence of PIF. The present invention further relates to PIF peptides which, when added to Jurkat cell cultures, have been observed to either (i) decrease binding of anti-CD2 antibody to Jurkat cells; (ii) increase expression of CD2 in Jurkat cells; or (iii) decrease Jurkat cell viability. In additional embodiments, the present invention provides for ELISA assays which detect PIF by determining the effect of a test sample on the binding of anti-CD2 antibody to a CD2 substrate.
Patent IL-169135-A0 (IL)
Title: A method for depositing a metal layer on a semiconductor interconnect structure having a capping layer
IPC: H01L21/768
Filed: 2005-06-14
Abstract: Disclosed is a method for depositing a metal layer on an interconnect structure for a semiconductor wafer. In the method, a metal conductor is covered by a capping layer and a dielectric layer. The dielectric layer is patterned so as to expose the capping layer. The capping layer is then sputter etched to remove the capping layer and expose the metal conductor. In the process of sputter etching, the capping layer is redeposited onto the sidewall of the pattern. Lastly, at least one layer is deposited into the pattern and covers the redeposited capping layer.
Patent IL-178474-A0 (IL)
Title: Monoclonal antibodies to hepatocyte growth factor and pharmaceutical compositions containing the same
IPC: G01N33/577
Filed: 2006-10-05
Abstract: The present invention is directed toward a neutralizing monoclonal antibody to hepatocyte growth factor, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient.
Patent IL-179740-A0 (IL)
Title: Non-integrative and non-replicative lentivirus, preparation and uses thereof
IPC: A61K35/76
Filed: 2006-11-30
Abstract: The invention concerns a non-integrative and non-replicative recombinant lentivirus as well as its uses, in particular for preparing a composition for transferring genes in vitro, ex vivo or in vivo. The invention is useful for transferring genes in any mammal organism, for example in liver, muscle, pancreas or central nervous system (including the ocular sphere) tissues or cells, and in particular for treating disorders or pathologies such as, for example, central nervous system, including the ocular sphere, disorders.
Patent IL-180169-A0 (IL)
Title: A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line
Filed: 2006-12-19
Abstract: The present invention provides a structural characterization platform that can be used to assess the stability of a polyclonal cell line during production, as well as batch-to-batch consistency of the final polyclonal products. The structural characterization platform is based on genetic analyses as well as protein characterization techniques that alone or in combination provide the necessary information to characterize the polyclonal cell line and final products. The collection of different homologous proteins to be analyzed with the platform techniques is for example a recombinant polyclonal antibody or a mixture of monoclonal antibodies.
Patent RO-127521-A0 (RO)
Title: Complex disinfecting composition with bactericidal, fungicidal and virucidal effect
Inventor: COMAN AURELIA
IPC: C11D1/68
Filed: 2011-08-29
Abstract: The invention relates to a complex disinfecting composition with bactericidal, fungicidal and virucidal effect. According to the invention, the composition comprises 0.5...20 parts of oxygenated water, 0.5...20 parts of isopropyl alcohol, 0.1...10 parts of benzalkonium chloride and distilled water for the remainder up to 100 parts, the parts being expressed by weight.
Patent RO-132542-A0 (RO)
Title: Biocomposite porous material and process for preparing the same
Inventor: SIMA GABRIELA
IPC: A61L27/56
Filed: 2017-09-27
Abstract: The invention relates to a biocomposite porous material to be used in bone reconstruction and to a process for preparing the same. According to the invention, the material consists of 45...50% hydroxyapatite, 37...43% titanium dioxide, 4...9% calcium carbonate and 5...8% calcium phosphate. The process, as claimed by the invention, consists in homogenizing the components as powder, by mixing them at a temperature of 240°C, gradually cooling the mixture down to the ambient temperature while adding usual conditioning agents and mould pressing to obtain a raw semiproduct which is subjected to sintering, in two steps, resulting in a material of nanometric sintered crystalline hydroxyapatite structure having a grain size of 200...800 nm, reinforced with a micronic crystalline titanium dioxide structure having a grain size of 15...110 μ m, porosity of 32...43%, a transverse elasticity modulus of 410...550 MPa, compression resistance of 30...60 MPa and elongation of 6...11%.
Patent AP-2000002002-A0 (AP)
Title: Method of treatment.
Inventor: STEINER MARTIN X
IPC: A61P43/00
Filed: 1999-06-16
Abstract: A method for promoting smoking cessation or reduction or preventing relapse smoking, comprises administering an effective, non-toxic amount of paroxetine or a pharmaceutically acceptable salt or solvate thereof, to human in need thereof.
Patent MA-27244-A1 (MA)
Title: Dispositif de fixation de portemanteaux
Inventor: ERUM PASCUAL JUAN MANUEL
IPC: A47G25/48
Filed: 2004-08-12
Abstract: DISPOSITIF DE FIXATION DE PORTEMANTEAUX (1) Comprend une zone annulaire (1) prévue pour être introduite dans le crochet classique (6) d'un portemanteau et prolongée par une espèce de languette (3) orientée à peu près perpendiculairement à ladite zone annulaire (1), ladite languette (3) étant munie d'un arceau (4) qui facilite l'introduction d'un autre crochet classique (6) de portemanteau et un élément d'accrochage étant présent sous l'arceau (4) pour ledit autre crochet classique.
Patent MA-27634-A1 (MA)
Inventor: PRUSCHY MARTIN
IPC: A61K31/427
Filed: 2005-09-23
Abstract: This invention relates to organic compounds of formula (I) in particular to pharmaceutical compositions for use in combination with ionizing radiation for the delay of progression or treatment of a proliferative disease, especially a solid tumor disease.
Patent MA-27925-A1 (MA)
Title: Combinaisons d'un inhibiteur de cathepsine k et d'un bisphophonate utilisees dans le traitement des metastases osseuses, de la croissance des tumeurs et de la perte osseuse induite par une tumeur
Inventor: ZIMMERMANN JOHANN
IPC: A61K31/505
Filed: 2006-01-18
Abstract: "COMBINAISONS D'UN INHIBITEUR DE CATHEPSINE K ET D'UN BISPHOSPHONATE DANS LE TRAITEMENT D'UNE METASTASE OSSEUSE, D'UN DEVELOPPEMENT DE CELLULES CANCEREUSES ET D'UNE PERTE OSSEUSE INDUITE PAR UNE TUMEUR" La présente invention concerne des préparations pharmaceutiques comprenant certains types de bisphosphonates et certains types d'inhibiteurs de cathepsine K, en particulier dans la prévention et le traitement de métastases osseuses, d'une hypercalcémie induite par une tumeur, d'un développement de tumeur, d'une perte osseuse induite par une tumeur et de maladies se manifestant par une perte osseuse telles que l'ostéoporose ou une perte osseuse induite par une thérapie anti-cancéreuse.
Patent MA-28294-A1 (MA)
Title: Procede de preparation de phosphates de bases fortes
Inventor: TAKHIM MOHAMED
IPC: C01B25/30
Filed: 2006-07-13
Abstract: Procédé de préparation de phosphates de bases fortes, comprenant une formation d'une pulpe constituée d'une phase aqueuse contenant du phosphate de calcium soluble dans l'eau, et d'une phase solide contenant des impuretés, une séparation entre ces phases, un déplacement dans la phase liquide des ions calcium par des ions d'une base forte avec formation d'une solution aqueuse de phosphate(s) pur(s) de ladite base forte et précipitation d'un phosphate de calcium pur insoluble dans l'eau, procédé dans lequel on mélange minerai et acide phosphorique de façon à obtenir une composition pâteuse de triple superphosphate à laquelle on ajoute de l'eau pour obtenir ladite pulpe.
Patent MA-37465-A1 (MA)
Title: Cornue verticale de surface et procédé pour obtenir de l'huile et du gaz à partir de schiste pyrobitumineux et/ou de matières contenant des composés carbonés organiques
Inventor: WINCK JOÃO CARLOS
IPC: C10G1/00
Filed: 2013-03-27
Abstract: L'invention porte sur une cornue (100) de surface à axe vertical, chauffée par une source externe, qui comprend (i) un tuyau central multifonctionnel (110), (ii) un dispositif d'étanchéité supérieur (120), (iii) un système (130) de distribution de charge, (iv) une cuve (140) de distillation en cornue à lit de forme annulaire (141) garnie d'un ensemble de tuyaux (142) de charge, espacés entre eux, pour former une chambre de collecte de gaz et de brouillard (143), un injecteur (144) de gaz chaud, un collecteur (145) et un distributeur (146) de recyclat froid et un mécanisme (147) de régulation et de déchargement du lit, (v) une chambre de répartition (150), (vi) un dispositif pour la récupération de chaleur du schiste usé (160) contenant un réseau de tuyauterie (162) pour la recirculation et la pulvérisation de l'eau de distillation en cornue et des trémies d'accumulation (161), et (vii) un dispositif d'étanchéité (170) de fond à sec. De plus, cette invention porte sur un procédé pour obtenir de l'huile et du gaz à partir de schiste pyrobitumineux et/ou de matières qui contiennent des composés organiques à l'aide de la cornue verticale de surface susmentionnée chauffée par une source externe (100) grâce aux étapes suivantes : (a) l'alimentation en charge, (b) l'étanchéification de l'alimentation en charge, (c) la distribution de la charge, (d) la collecte et l'élimination de gaz et de brouillard, (e) le chauffage et le séchage de la charge, (f) la réinjection de courant de gaz du recyclat de gaz froid provenant de l'étape (i), (g) la pyrolyse de la charge, (h) l'injection du courant de gaz provenant du recyclat de gaz chaud, (i) l'élimination du courant de recyclat de gaz froid, (j) la récupération de chaleur du schiste usé, (k) l'évacuation du lit de forme annulaire, (l) l'injection de recyclat de gaz froid, (m) le mélange du courant de recyclat froid avec un courant de vapeur d'eau, (n) la collecte dans les trémies d'accumulation du schiste usé évacué, (o) la pulvérisation de l'eau de distillation en cornue recyclée, (p) la production de vapeur par le contact de l'eau de distillation en cornue recyclée avec la matière distillée en cornue déposée dans les trémies d'accumulation, et (q) l'évacuation à sec du schiste usé et l'étanchéification de fond.
Patent MA-39229-A1 (MA)
Title: Pyrrolidines, térahydrofuranes et cyclopentanes substitués utiles en tant qu'antagonistes des récepteurs des orexines
Inventor: FIELDHOUSE CHARLOTTE
IPC: C07D401/04
Filed: 2015-02-19
Abstract: L'invention concerne des composés représentés par la formule (i), ainsi que des sels pharmaceutiquement acceptables de ceux-ci; dans la formule (i), l, x, ra, rb, r 1, r2 et r3 sont tels que définis dans la description. L'invention se réfère également à des procédés de préparation de ces composés, à des compositions pharmaceutiques contenant ceux-ci et à leur utilisation thérapeutique.
Patent MA-41764-A1 (MA)
Title: Contenant à l'épreuve des enfants et son procédé de fabrication
Inventor: BRESSAN MICHEL
IPC: B65D5/66
Filed: 2016-05-20
Abstract: La présente invention concerne un contenant à l'épreuve des enfants (1) comprenant : un logement (2) composé d'un matériau de feuille définissant un volume interne (3) et présentant une ouverture de passage (5) délimitée par un bord libre (6), un système de fermeture (7) composé d'un matériau de feuille configuré pour définir une condition ouverte et fermée du logement (2), le système de fermeture (7) comprend une languette (8) présentant une partie de fermeture (9) mobile par rapport au bord libre de log
Patent UY-24047-A1 (UY)
Title: Circuito convertidor de alimentacion
Inventor: JOSE ANTONIO POZAS ALVAREZ
IPC: H02M3/24
Filed: 1995-09-27
Abstract: Circuito convertidor de alimentación, que consiste en un circuito que sumnistra la tensión necesaria para las diferentes placas del sistema de moderniazación de centrales telefónicas electromecánicas, configurado como un convertidor DC/DC por modulación de anchura de pulsos en modo corriente y basado en la topología FLYBACK, prporcionando tres tensiones de alimentación diferentes, reguladas y protegidas contra cortocircuito y sobrecarga, estando además aisladas entre sí con respecto a la tensión de entrada siendo dos de ellas iguales y opuestas en signo,
Patent UY-30563-A1 (UY)
Title: Indoxacarb y mezclas neonicotinoides del mismo
Inventor: PEDRONI DOMINGOS
IPC: A01N25/00
Filed: 2007-08-30
Abstract: Un método para controlar o prevenir el dano causado por una o más plagas de coleopteros habitantes del suelo, como por ejemplo las larvas de los mismos, en un material de propagacion de plantas, una planta, parte de una planta y/o un organo de una planta que se desarrolla en un momento posterior, que comprende la aplicacion al material de propagacion de plantas de una cantidad efectiva de indoxacarb. También se presenta una mezcla que comprende (a) indoxacarb y (b) uno o más compuestos neonicotinoides indicados.
Patent UY-30633-A1 (UY)
Title: 4-[4-({[4-cloro-3-(trifluorometil)fenil]carbamoil}amino)-3-fluorofenoxi]-n-metilpiridin-2-carboxamida monohidratada
Inventor: KEIL BIRGIT
IPC: A61K31/44
Filed: 2007-10-08
Abstract: La presente invencion se refiere a 4-[4-({[4-cloro-3-(trifluorometilfenil]carbamoil}amino)-3-fluorofenoxi]-N-metilpiridin-2-cazrboxamida monohidratada, a procedimientos para su preparacion, a composiciones farmacéuticas que la comprenden y a su uso en el control de trastornos.
Patent UY-31309-A1 (UY)
Title: Anticuerpos anti-cxcr5 humanizados, derivados de los mismos y su uso
Inventor: BAURIN NICHOLAS
IPC: A61K39/00
Filed: 2008-08-27
Abstract: La presente invencion se refiere a anticuerpos humanizados que se unen específicamente a CXCR5 y, por ejemplo, pueden inhibir la funcion de CXCR5. La invencion también incluye usos de los anticuerpos para tratar o prevenir enfermedades o trastornos relacionados con CXCR5
Patent UY-31325-A1 (UY)
Title: Composiciones y métodos para tratar enfermedades y trastornos inmunologicos e inflamatorios
Inventor: ORAVECZ TAMAS
IPC: A61K31/4164
Filed: 2008-09-05
Abstract: Se describen métodos y composiciones para tratar enfermedades y trastornos inmunologicos e inflamatorios. Los métodos y composiciones particulares comprenden la administracion de un agente que inhibe la actividad de S1P liasa y al menos un agente inmunosupresor y/o antiinflamatorio adicional.
Patent DZ-3258-A1 (DZ)
Inventor: MONNOM OLIVIER
IPC: H03K17/082
Filed: 2000-07-11
Granted: 2001-01-25
Abstract: The active clamping control method involves using at least one power interrupter connected to a clamping device with a voltage threshold, preferably connected between the power terminal and the control of interrupter. In this way the maintenance of maximum allowable voltage at the interrupter poles is ensured, by inhibiting the clamping function when the interrupter is off. The mechanism for maintaining the maximum allowable voltage includes an inhibition interrupter connected between the clamping device and the control of power interrupter. Independent claims are included for an active control device.
Patent ES-155874-A1 (ES)
Title: Sistema de imitacion de carrera para inyectores de carburantes
IPC: F02M61/08
Filed: 1942-01-31
Abstract: La propiedad y explotación exclusivas de un sistema de limitación de carrera para inyectores de carburante cerradoscaracterizado por inmovilizarse en el inyector el casquillo que rodea la agujaen correspondencia del muelle de válvulay que sirve para limitar la carrera.
Patent ES-181534-A1 (ES)
Title: MEJORAS INTRODUCIDAS EN LAS LLANTAS NEUMáTICAS
Filed: 1948-01-03
Abstract: Mejoras introducidas en las llantas de ruedas neumáticas compuestas, caracterizadas por el hecho de que los componentes de las llantas son dos cintas sin fin interconectables.
Patent ES-199821-A1 (ES)
Title: UN APARATO PARA DEPURACIoN DE MERCURIO
Filed: 1951-10-02
Abstract: Aparato para depuración de mercurio que se caracteriza por un tubo o recipiente electrolizador, vertical, en el que por la parte superior desembocan dos depósitos suministradores, de mercurio a purificar uno y de puro electrolito otro, provistos ambos de su llave correspondiente y el primero además de una tobera de pequeño diámetro; en la parte inferior van instalados dos sifones de salida constante, uno, en el mismo fondo en el cual, a la vez, sirve de decantación de impurezas restantes y determina el nivel y cantidad de mercurio depurado retenido en el fondo del recipiente, y, el otro, a un lado y sobre el nivel o capa superior de mercurio antedicha, para evacuar el exceso o capas inferiores del electrolito y las impurezas combinadas con los aniones en estado naciente que se desprenden, señalando también la altura del líquido en el tubo electrolizador.
Patent ES-279857-A1 (ES)
Title: Improvements relating to insulators
IPC: H01B1/00
Filed: 1962-08-07
Abstract: A ceramic insulator with a coating containing a semi-conducting material is produced by applying to an unfired ceramic insulator a coating reducible to a semi-conducting material, firing the insulator to mature the ceramic and thereafter subjecting the insulator to a second firing in a reducing atmosphere. When a glaze containing titania is used as the coating material, molybdenum disilicide or silicon may be added. Reference has been directed by the Comptroller to Specifications 678,718 and 848,034.
Patent ES-344165-A1 (ES)
Title: Basic monoazo dyestuffs
IPC: C09B44/04
Filed: 1967-08-16
Abstract: Basic monoazo dyestuff of the formula where R is alkyl, R1 is phenyl or substituted phenyl, R2 and R3 are various organic substituents and X is an anion, which dyestuffs are useful in dyeing polyvinyl chloride, polyamide, polyurethane, polyester and especially polyacrylonitrile fibers with intense, level dyeings having good fastness to light and other good general fastness properties, having good stability within a wide pH range, having good affinity in aqueous solutions at different pH values and usually reserving wool wall.
Patent ES-349318-A1 (ES)
Title: 4,5,6,7-tetrahydro-thiazolo-[5,4-c]pyridines
IPC: A61K/
Filed: 1968-01-15
Abstract: Novel compounds of the formula (wherein R 1 is H, C 1-6 alkyl, C 2-6 alkenyl, halo C 2-6 alkenyl, C 3-8 cycloalkyl, C 6-10 aryl, C 7-9 aralkyl, aromatic or aliphatic carboxylic or sulphonic acyl, carbamoyl or amidino R 2 is H, C 1-6 alkyl, C 2-6 alkenyl, halo C 2-6 alkenyl, or cycloalkyl, or NR 1 R 2 is a heterocyclic ring which may contain a further hetero atom and/or be OH, methyl or phenyl substituted R 3 is H, C 1-6 alkyl, C 2-6 alkenyl, halo C 2-6 alkenyl, C 3-8 cycloalkyl, C 6-10 aryl, C 7-9 aralkyl, aromatic or aliphatic carboxylic or sulphonic acyl, carbamoyl, thiocarbamoyl or amidino and where alkyl groups R 1 , R 2 and/or R 3 may be OH, alkoxy, aryloxy, cycloalkyl, carboxy, carbalkoxy or amido substituted, and aromatic groups R 1 , R 2 and/or R 3 may be halogen, OH, alkyl, alkoxy, alkylthio, alkylsulphonyl, alkylenedioxy, amino, alkylamino, acylamino or aminosulphonyl substituted. R 4 and R 5 are H, alkyl, aryl or aralkyl and R is a bond or a C 1-3 hydrocarbon chain) and acid-addition salts thereof, are prepared from hydrohalic acid salts of the appropriate 3-bromo-4-piperidones and thioureas or thioamides. Products wherein R 3 is aryl may be hydrolysed, provided R 1 is not aryl, to the corresponding compounds wherein R 3 is H, which compounds may in turn be reacted with appropriate reagents to replace the H atom R 3 by another radical or group R 3 (except aryl).
Patent ES-354334-A1 (ES)
Title: Improvements in window regaulator crank handles for automotive vehicles
IPC: G05G1/08
Filed: 1968-05-25
Abstract: A vehicle window operating mechanism crank handle comprises a base member 1, fitted with a splined connector 2, and a resilient cover 3 fixed to the base by a solid or hollow stud 7 and by fitting over a pivot pin 4 on which a knob 6 is force fitted. The knob is closed by a cup 5 and a nut used to retain the handle on the operating mechanism occupies a space 10. The cover may be injection moulded from plastics material or be made solid from a similarly resilient material. In the case of a solid cover, reinforcing members may be embedded therein and formed with a protruding lug which grips the base member 1.
Patent ES-360394-A1 (ES)
Title: A transfer process for dyeing, printing or decorating articles
IPC: D06P5/24
Filed: 1968-11-18
Abstract: A process for decorating, dyeing or printing articles comprises applying to a support at least one dyestuff, resist or discharge agent, mordant, fluorescent or phosphorescent product adapted to be transferred on to the article, applying the support thus treated against the article to be decorated, dyed or printed and subjecting the support and article to pressure at an elevated temperature and in humid conditions whereby transfer is effected without the aid of a binder for retaining the product or agent on the article. The article may be a fleece or web of non-woven fibres, thread or yarn. woven or knitted fabric or lace or article of clothing, paper, wood, leather, rubber or natural or synthetic resin. The support may be a sheet of paper, metallic sheet, or a fibrous web. Silk, wool, polyamides polyacrylonitriles, polyurethanes, polyesters and cellulose acetates may be treated with acid, basic, disperse and reactive dyes.
Patent ES-364327-A1 (ES)
Title: Load weight circuit for traction motor control systems
IPC: B60L9/04
Filed: 1969-03-03
Abstract: A voltage signal VR represents the desired tractive or braking effort to be supplied by traction motors M1-M4, a voltage signal VL being proportional to the weight of the vehicle. A transistor 5 is turned on when a ramp voltage V1 exceeds the voltage VR, the voltage V2 varying between the values VL and zero according to the state of conduction of the transistor. The filtered voltage V3 is proportional to both the signals VL and VR and is added as bias to the voltage VR to develop a signal across lines 15, 16, which causes the motors to provide the desired tractive or braking effort modified in accordance with the car weight. The motor current is controlled by chopper 23 comprising a main thyristor 24 associated with a commutating capacitor 25 and turn-off thyristor 26, as well as an auxiliary thyristor 27 and reactor 28. For power operation, the motors are connected in parallel, a free-wheeling diode 37 being included in the motor circuit. Two loop circuits are formed for braking, the common branch including resistors 35, 36. The chopper 23 is controlled by pulse generators 39, 40, in accordance with a comparison between the motor currents and the signal across lines 15, 16. A control signal on line 42 is modified by delay circuit 44 to provide the signal VR. A transductor 45 carries the total motor current in either the power or braking connection, its rectified output being applied across Zener diode 50 and resistor 51. The control signal from the load-compensating circuit 1 is developed across capacitor 52, whilst lines 53, 54, convey the triggering signals to the pulse generators 39, 40. The voltage-drop across diode 50 determines the amount of ripple in the motor current.