baber/WOPTO huggingface dataset:
Patent NZ-521255-A (NZ)
Title: Methods to impair hematologic cancer progenitor cells and compounds related thereto
Inventor: JORDAN CRAIG T
IPC: A61K51/10
Filed: 2001-03-06
Abstract: Primitive or progenitor haematologic cancer cells have been implicated in the early stages and development of leukaemia and malignant lymphoproliferative disorders, including acute myelogenous leukaemia (AML), chronic myelogenous leukaemia (CML) and chronic lymphoid leukaemia (CLL). Interleukin-3 receptor alpha chain (IL-3R alpha or CD123) is strongly expressed on progenitor haematologic cancer cells, but is virtually undetectable on normal bone marrow cells. Described are methods of impairing progenitor haematologic cancer (e.g., leukaemia and lymphomic) cells by selectively targeting cells expressing CD123. These methods are useful in the detection and treatment of leukaemias and malignant lymphoproliferative disorders. Also provided are compounds useful for selectively binding to CD123 and impairing progenitor haematologic cancer cells. These compounds may include cytotoxic moieties such as, for example, radioisotopes or chemotherapeutics.
Patent NZ-522849-A (NZ)
Title: Methods for treating MS by inhibiting astrocyte proliferation in the brain with interferon 2-beta, thereby reducing inflammation
Inventor: CROZE EDWARD M
IPC: A61P25/28
Filed: 2001-06-18
Abstract: Described are nucleic acids and polypeptide sequences that code for an interferon-beta-2 ("IFN-beta2"). A pharmaceutical composition, which comprises a pharmaceutically acceptable excipient and a therapeutically effective amount of a human IFN-beta2 polypeptide, biologically active fragment thereof, or biologically-active derivative thereof, is useful in treating multiple sclerosis in humans. The graph depicts the antiviral activity of IFN-beta2 and IFN-beta1b. Human WISH cells were stimulated with either IFN-beta1b or IFN-beta2 followed by infection with vesicular stomatitis virus (VSV). Viral cytopathic effect (CPE) was measured using the redox dye Alamar Blue. Units of antiviral activity corresponding to IFN-beta1b are plotted along the X-axis. Specific antiviral activity of IFN-beta2 was determined to be 4.0-8.0 x106 International Units ("IU") per mg. Using this assay, IFN-beta2 demonstrates functional properties similar to those of IFN-beta1b.
Patent NZ-524414-A (NZ)
Title: Method and apparatus for high data rate transmission in a wireless communication system
Inventor: BENDER PAUL
IPC: H04J13/00
Filed: 2001-09-12
Abstract: In a wireless communication system (32) a method for high data rate transmission aggregates information signals processed by at least two modems (38, 40, 42), wherein the modulated information signals are transmitted using two carrier frequencies. The method provides multiple data transmissions concurrently over a broad bandwidth consistent with single transmission air-interface standards. An apparatus, mobile unit (34), includes a multi-link (ML) protocol processor (36) that aggregates the information signals from the modems (38, 40, 42) into a point-to-point protocol (PPP) format for interface with conventional data-based systems, such as the internet. The ML processor (36) further receives an aggregate bundle and separates the bundle into its constituent parts for modulation by the modems (38, 40, 42).
Patent NZ-526925-A (NZ)
Title: Treatment of male sexual dysfunction
Inventor: NAYLOR ALASDAIR MARK
IPC: G01N33/68
Filed: 2001-12-10
Abstract: The use of an inhibitor of a neuropeptide Y receptor (NPY), preferably of a NPY Y1 receptor, which inhibitor is selective for an NPY or NPY Y1 receptor associated with male genitalia, in the treatment of male erectile dysfunction (MED) and in the preparation of a medicament for the treatment or prevention of MED.
Patent NZ-532582-A (NZ)
Title: Extruded reconstituted tobacco filament
Inventor: LEWIS WILLIAM DAVID
IPC: A24B15/14
Filed: 2001-05-08
Abstract: A method for the extrusion of filamentary strands of reconstituted tobacco through a die plate and the downstream handling thereof is disclosed, wherein the die plate is configured such that each filament is of a square or rectangular cross-section, the downstream handling of which effects draw down of the extruded filament. Further the extruded reconstituted tobacco filament has a substantially rectangular or square cross-section and comprises a cellular interior having an integral skin extending over at least the four sides of the filament. (62) Divided out of 522456
Patent NZ-532837-A (NZ)
Title: Remote monitoring and control of a motorized vehicle allowing diagnostic and despatch functions
Inventor: MAVREAS MICHAEL
IPC: G08G1/123
Filed: 2002-11-14
Abstract: Remote monitoring and control of a motorized vehicle is performed using a communications and control hub connected directly to an onboard diagnostic port of the vehicle. An auxiliary onboard diagnostic port is provided to permit technicians to perform diagnostics on the vehicle. All vehicle monitoring and control is effected without an auxiliary wiring harness. The communications control hub is particularly useful for fleet management and dispatch systems.
Patent NZ-534587-A (NZ)
Title: Pharmaceutical composition containing 5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid to treat a cyclooxygenase-2 dependent disorder
Inventor: KARNACHI ANEES ABDULQUADAR
IPC: A61K9/28
Filed: 2003-03-06
Abstract: A solid pharmaceutical composition for treating a cyclooxygenase-2 dependent disorder or condition is disclosed, wherein the solid pharmaceutical composition comprises between about 200 and about 400 mg of 5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid, wherein the residual moisture levels of said composition is between about 1.5% and about 5%.
Patent NZ-538160-A (NZ)
Title: Process for the preparation of phenylalanine enamide derivatives
Inventor: SKEAD BENJAMIN MARK
IPC: C07D471/04
Filed: 2003-07-16
Abstract: A process for the preparation of a class of phenylalanine enamide derivatives of formula (1) is disclosed, wherein: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a linker group selected from -N(R4)- [where R4 is a hydrogen atom or an optionally substituted straight or branched C1-6alkyl group], -CON(R4)-, or -S(O)2N(R4)-; R1 is a carboxylic acid (-CO2H) or a derivative or biostere thereof; R2 is a hydrogen atom or a C1-6alkyl group; Rx, Ry and Rz which may be the same or different is each an atom or group -L1(Alk1)n(R3)v; and the salts, solvates, hydrates and N-oxides thereof; which comprises reacting a compound of formula (2): wherein: Qa is a group -N(R4)H; and the salts, solvates, hydrates and N-oxides thereof; with a compound Ar1W wherein W is a group selected from X1 (wherein X1 is a leaving atom or group), -COX2 (wherein X2 is a halogen atom or a -OH group) or -SO2 X3 (in which X3 is a halogen atom).
Patent NZ-538162-A (NZ)
Title: High molecular weight cationic polymers obtained by post-polymerisation crosslinking reaction
Inventor: SONG ZHIQIANG
IPC: B01D21/01
Filed: 2003-07-30
Abstract: A method for the preparation of an aqueous cationic polymer solution is disclosed, wherein the method comprises: (a) polymerizing substantially all of a monomer component having at least one monomer having a cationic functional group by reaction initiated from a free radical initiator to form a base cationic polymer solution; (b) contacting the base cationic polymer solution with additional free radical initiator to cause multiple cationic polymer groups to form interconnecting bonds so that said base cationic polymer solution forms an aqueous solution containing a multi-crosslinked cationic polymer having a higher molecular weight than the base cationic polymer. The molecular weight of cationic polymers, such as the quaternary ammonium polymers of diallyldialkyl ammonium chloride, can be increased by controlled addition of a water-soluble radical initiator at an elevated reaction temperature with agitation to prepare high molecular weight, crosslinked, water-soluble cationic polymers.
Patent NZ-540288-A (NZ)
Title: Target for therapy of cognitive impairment
Inventor: GALLAGHER MICHELA
IPC: C12Q1/68
Filed: 2003-11-24
Abstract: Provided is the use of valproic acid and related compounds for preparation of a medicament for treating Mild Cognitive Impairment (MCI) in a mammal, including human.
Patent NZ-541567-A (NZ)
Title: Thermoplastic film sealing under vacuum
Inventor: CADY DERRIL R
IPC: B65B31/02
Filed: 2004-01-13
Abstract: A device for sealing thermoplastic film on a chicken packaging line, includes a sealing support assembly 206 to receive the film 120, a sealing bar assembly including an electrically heated sealing bar 350 and a heat sink plate 360 positioned proximate the sealing bar to receive heat therefrom, and a bellows assembly 308, 310 to lower the sealing bar assembly to engage and seal the film and raise the assembly to disengage the assembly from the film. A vacuum chamber cover 302 with a lower rim 304 can be lowered so that the rim engages the upper surface of the platen 202 to form a vacuum chamber whereby a vacuum can be drawn within the chamber, or can be raised to an open position separated from the platen. The sealing assembly operates to seal the film under vacuum in the vacuum chamber.
Patent NZ-543867-A (NZ)
Title: Modified fluorinated nucleoside analogues
Inventor: CLARK JEREMY
IPC: C07H19/00
Filed: 2004-04-21
Abstract: Disclosed are (2'R)-2'-deoxy-2'-fluoro-2'-C-methyl nucleosides and their pharmaceutically acceptable salts, wherein the substituents are as defined in the specification. The compounds are useful for treating Flaviviridae infections, including hepatitis C virus, West Nile Virus, yellow fever virus and rhinovirus infections.
Patent NZ-549862-A (NZ)
Title: Progesterone receptor modulators
Inventor: HAMERSMA JOHANNES ANTONIUS MARIA
IPC: C07J53/00
Filed: 2005-03-18
Abstract: Disclosed are progesterone receptor modulating steroids of formula (I) which have both agonistic and antagonistic modulating activities towards the progesterone receptor, processes for their preparation, and their use in therapy, wherein the variables shown in formula (I) are as defined in the specification. These compounds of formula (I) are suitable for the treatment of endometriosis, for hormone replacement therapy or for the treatment of a gynaecological disorder, and as a contraceptive.
Patent NZ-550084-A (NZ)
Title: Releasable toilet seat assembly
Inventor: VIERKANT ERICH C
IPC: A47K13/12
Filed: 2005-03-30
Abstract: An assembly for releasably mounting a toilet seat and cover to a toilet base is disclosed. The assembly includes fasteners that attach deflectable extension arms of base member, to which is pivotally coupled the toilet seat and cover, to the toilet. The arms engage ring mounts disposed about the fasteners, where the arms flex outward slightly during mounting and dismounting achieved by a simple horizontal sliding motion. When connected, hinged covers snap onto the pair of arms to cover the fasteners and prevent deflection of the arms and thus separation of the base member(s) from the fasteners.
Patent NZ-550950-A (NZ)
Title: Electronic thermometer with a probe tip on a flexible shaft
Inventor: SISK RICK A
Filed: 2006-10-31
Abstract: An electronic thermometer constituted by a probe tip 25 measuring the temperature of a subject and a flex circuit consisting of a deformable electrically conductive substrate 33 connected to one or more temperature sensors for detecting the temperature of the probe. The end of the probe shaft is configured to receive the flex circuit in a final position by deforming it around four posts 56a,59b,59c,59d thus removing the need for an epoxy.
Patent NZ-554004-A (NZ)
Title: Cooling storage, typically for showcase refrigerator, with cooling unit pressed up against apertured storage chamber by bent circular steel rod(s)
Inventor: IGUCHI HARUNOBU
Filed: 2007-03-21
Abstract: In order to press a cooling unit R against the underside of a storage chamber (not shown) bent circular section steel rods press-up members 44 are used.
Patent NZ-554213-A (NZ)
Title: Modified release ibuprofen dosage form
Inventor: HITE MICHAEL
IPC: A61K9/22
Filed: 2005-09-30
Abstract: The disclosure relates to a solid dosage form for modified oral administration of ibuprofen comprising: i) a hydrophilic polymer; ii) 300 to 800 mg of ibuprofen in the solid dosage form uniformly dispersed in said polymer; iii) a dissolution additive dispersed in said hydrophilic polymer in an amount in the range of 10% to 35% by weight of the ibuprofen, said dissolution additive comprising an alkali metal salt, an amino acid having a neutral to alkaline side chain, croscarmellose or a salt thereof, or a combination of any two of such dissolution additives; and an inert formulation additive dispersed in said hydrophilic polymer in an amount in the range of 15% to 75% by weight of the ibuprofen, said formulation additive comprising microcrystalline cellulose, silica, magnesium stearate, stearic acid, lactose pre-gelatinized starch, dicalcium phosphate or a combination of any of them, wherein at least 20% of the ibuprofen is released within 2 hours following oral administration or exposure to an agitated aqueous medium of a single dosage unit, then thereafter releases ibuprofen at a relatively constant rate over a period of at least 8 hours, and wherein at least 70% of the ibuprofen is released over a period of not more than 14 hours following such administration or exposure. The disclosure also relates to use of the dosage form in the preparation of medicaments for the treatment of inflammation.
Patent NZ-555801-A (NZ)
Title: Pressure regulated continuously variable volume container for fluid delivery
Inventor: NEAS EDWIN DEAN
IPC: B65D33/36
Filed: 2005-12-02
Abstract: A fluid delivery system for a microfluidic device 24 comprises a fluid containing variable volume container 1 with an almost completely flexible wall and a conduit 8 to the microfluidic device 24. Gas pressure in the range of 10 to 200 psi is applied to the flexible wall of the container 1 to compress the container 1 and cause fluid to flow into the conduit 8. This method prevents the contamination of the fluid. .
Patent NZ-561188-A (NZ)
Title: Packaging system for storage and microwave heating of food products
Inventor: KWIAT CHRISTINE LOUISE
IPC: A23L13/60
Filed: 2007-09-05
Abstract: The packaging system includes a first food product sealed within an inner wrapper, a second food product positioned within a tray and spacing the first food product from the tray, and an outer wrapper sealing the first food product, sealed within the inner wrapper, the second food product, and the tray therein. A shield is disposed on the tray, and is in contact with more than one surface of the second food product. The inner and outer wrappers are removed before microwave heating.
Patent NZ-563185-A (NZ)
Title: Lock assembly adaptor
Inventor: CONSTANTINOU JOHN
Filed: 2007-11-05
Abstract: The disclosure relates to an adaptor 14 for use with a lock assembly 1. The adaptor includes a mount 15 which is fixed in position relative to a housing 12 of the lock assembly 1. A detent 18 is movable relative to the mount 15 between an inactive position whereby the bolt is movable relative to the housing to an extended lock position, and an inactive position whereby the bolt is not movable relative to the housing to a lock position. The adaptor also includes biasing means 20 for urging the detent 18 towards the active position.
Patent NZ-567017-A (NZ)
Title: Canine influenza virus and related compositions and methods of use
Inventor: YOON KYOUNG-JIN
IPC: A61K39/145
Filed: 2006-10-17
Abstract: Disclosed is an isolated canine influenza virus of subtype H3N8 comprising an HA having SEQ ID NO: 4 or an amino acid sequence that is greater than 99% identical to SEQ ID NO: 4, with the proviso that the amino acids at positions 94 and 233 are identical to SEQ ID NO: 4. Also disclosed is a method of inducing an immune response to canine influenza virus in an animal comprising administering to the animal an aforementioned composition.
Patent NZ-568678-A (NZ)
Title: Methods of inducing terminal differentiation using suberoylanilide hydroxamic acid (SAHA)
Inventor: RICHON VICTORIA M
IPC: A61K9/20
Filed: 2003-03-04
Abstract: Disclosed is a crystalline form of suberoylanilide hydroxamic acid (SAHA) obtained by recrystallizing a crude preparation of SHA from a mixture of methanol and water. Also disclosed is a crystalline form of SAHA obtained by reacting suberic acid with aniline to obtain suberanilic acid, reacting the suberanilic acid with methanol to form methyl suberanilate, reacting the methyl suberanilate with hydroxylamine hydrochloride to form crude SAHA, and recrystallizing the crude SAHA from a mixture of methanol and water. (62) Divided Out of 550185
Patent NZ-569556-A (NZ)
Title: Resistance to ethylene susceptibility in lettuce
Inventor: VAN DUN CORNELIS MARIA PETRUS
IPC: A01H5/12
Filed: 2007-01-08
Abstract: A method for screening a population of plants to identify individuals that show a reduced susceptibility to ethylene and physiological disorders, in particular Russet Spotting and Yellowing. The method involves germinating a population of seeds in darkness and in the presence of ethylene to obtain seedlings that have a longer hypocotyl as compared to the original ethylene-sensitive control. Also disclosed are plants having reduced susceptibility to ethylene and have the NCIMB accession numbers 41449, 41450, 41448, 41451, 41452 and 41453. The plant can be a leafy vegetable, in particular lettuce.
Patent NZ-576823-A (NZ)
Title: Antibacterial quinoline derivatives
Inventor: GUILLEMONT JEROME EMILE GEORGES
IPC: C07D417/04
Filed: 2007-12-04
Abstract: Disclosed is a quinoline derivative compound of formula (Ia) or (Ib) as defined in the specification. The disclosed compound is used in the manufacture of a medicament for the treatment of a bacterial infection including Streptococcus pneumoniae, Staphylococcus aureus and Mycobacterium tuberculosis.
Patent NZ-579004-A (NZ)
Title: A feed roll for a harvester head and a method for manufacturing a feed roll
Inventor: NEUVONEN TIMO
IPC: A01G23/00
Filed: 2009-08-12
Abstract: A feed roll for a harvester head, comprising a fastening hub 1, a roll part 2 having a primarily circular cross section and surrounding the fastening hub, holding elements 3 on the outer surface of the roll part to provide the necessary hold between the outer surface of the roll part 2 and the tree trunk touching the same, a cogging 4 formed on at the least one rim of the roll part 2 to couple two adjacent feed rolls mechanically to each other, characterized in that further the cogging 4 is primarily at the level of the outer surface of the roll part 2, wherein the distance of the outer surface of the cogging from the rotation axis of the feed roll is primarily equal to the distance of the outer surface of the roll part from the rotation axis of the feed roll.
Patent NZ-579486-A (NZ)
Title: Inner shell intended for a gyratory crusher, and method of attaching such a shell on a crushing head
Inventor: ERIKSSON BENGT-ARNE
IPC: B02C2/04
Filed: 2008-04-28
Abstract: The inner replaceable shell 4 of a gyratory cone crusher is provided with projecting lugs 36 and bolt apertures near the top of the shell. The shell is placed on to the crushing head 3 from the narrow top portion 12 toward the wider bottom portion 10 so that the lugs 36 engage with the notches 38 in the crushing head 3 to prevent rotation of the shell with respect to the head, and bolts aligned parallel with the rotational axis of symmetry of the crusher head are tightened into threaded apertures 18 to hold the shell onto the head. Springs may be inserted to surround the bolts and between the top surface of the crushed head the bottom of the bolt flange of the shell so that even when the bolts are tightened there is axial movement possible between the head and the shell.
Patent NZ-581019-A (NZ)
Title: Collapsible Tray
Inventor: BENGE GEOFFREY CHARLES
IPC: A45F3/00
Filed: 2009-11-09
Abstract: A collapsible tray 10 comprises a base 15 with top and bottom surfaces where the base 15 is made up of a number of panels 20 25 30, and at least one retainer 45. The retainer 45 is attachable to the side of the base 15 such that in use it will position the panels 20 25 30 in an arrangement with respect to one another to form a substantially flat and contiguous surface. Adjacent panels are connected by at least one flexible joint.
Patent NZ-583461-A (NZ)
Title: Tubular filter including mesh and fibreglass fibres
Inventor: MURRAY CHRISTOPHER ADAM
IPC: E04H4/16
Filed: 2008-08-15
Abstract: A tubular filter assembly, comprising: a support member; and a filtratable element (201) surrounding the support member. The filtratable element comprises a backing mesh (202) and a fibrous batting comprising a plurality of individual fibres (301). The plurality of individual fibres are fiberglass. The individual fibres are pressed against the backing mesh when subjected to flow in a first direction, and extend from the fibrous backing mesh when subjected to flow in a second direction.
Patent NZ-589879-A (NZ)
Title: Induction of flocculation in photosynthetic organisms
Inventor: MENDEZ MICHAEL
IPC: C07K16/14
Filed: 2009-06-26
Abstract: Disclosed is a method of flocculating a non-vascular photosynthetic organism, comprising: a. expressing an exogenous nucleic acid encoding a first flocculation moiety as a cell surface component of a first non-vascular photosynthetic organism; and b. contacting said organism with a second flocculation moiety, thereby flocculating said organism.
Patent NZ-605920-A (NZ)
Title: Pharmaceutical compositions comprising r (+) budesonide and one or more bronchodilators
Inventor: MALHOTRA GEENA
IPC: A61K31/137
Filed: 2011-07-18
Abstract: Disclosed is a pharmaceutical composition comprising R (+) budesonide and one or more beta2-agonists selected from albuterol, levoalbuterol, terbutaline, pirbuterol, procaterol, metaproterenol, fenoterol, bitolterol mesylate, ritodrine, salmeterol, carmoterol, bambuterol, clenbuterol, indacaterol, milveterol, vilanterol, or olodaterol, and, optionally, one or more pharmaceutically acceptable excipients. The disclosed compositions may be used for relief from bronchial disorders, while simultaneously reducing undesirable side effects commonly experienced by corticosteroid users.
Patent NZ-606949-A (NZ)
Title: Human papillomavirus e7 antigen compositions and uses thereof
Inventor: WEBB JOHN R
IPC: A61K39/00
Filed: 2011-07-15
Abstract: Disclosed is a polypeptide comprising the amino acid sequence of three or more human papillomavirus (HPV) E7 antigens, wherein the polypeptide comprises an amino acid sequence as defined in the specification. Also disclosed is the use of the polypeptide to stimulate an immune response.