baber/WOPTO huggingface dataset:
Patent CR-20180387-A (CR)
Title: Triterpenoides modificados en c-3 y c-17 como inhibidores del vih-1
Inventor: YAN CHEN
IPC: C12N9/50
Filed: 2017-02-02
Abstract: Se exponen compuestos que tienen propiedades farmacológicas y que afectan a la bioactividad, sus composiciones farmacéuticas y procedimientos de uso. En particular, se proporcionan derivados de ácido betulínico que poseen actividad antivírica única como inhibidores de la maduración del VIH, tal como se representa mediante los compuestos de fórmula I: Estos compuestos son útiles para el tratamiento del VIH y del sida.
Patent EC-SP003645-A (EC)
Title: Aminoalcoxicarbazoles para el tratamiento de enfermedades del snc
Inventor: TENBRINK RUTH
IPC: C07D405/00
Filed: 2000-09-07
Abstract: La peresente invención proporciona aminoalcoxi derivados de carbazol, y más especificamente, proporciona compuestos de la fórmula (I) (gráfico), en donde R1, R2, R3, R4, R8, y R9 se describen en este documento. Estos compuestos son ligandos de la 5-HT y son útiles para tratar enfermedades en donde se desee modular la actividad de la 5-HT.
Patent EC-SP045418-A (EC)
Title: Formulacion de dosis alta de ibandronato
IPC: A61K31/675
Filed: 2004-10-29
Abstract: La invención se refiere a dosis altas de formulación oral de bisfosfonatos y a un proceso para la preparación de tales formulaciones.
Patent EC-SP045489-A (EC)
Title: Amidas de acidos 2-heteroarilcarboxilicos
IPC: A61K31/439
Filed: 2004-12-10
Abstract: La invención se refiere a nuevas amidas de ácidos 2-heteroarilcarboxílicos y a su uso para la preparación de medicamentos para el tratamiento y/o la profilaxis de enfermedades y para la mejora de la percepción, la capacidad de concentración, la capacidad de aprendizaje y/o la capacidad de memoria. en la que R1 significa 1-azabiciclo[2.2.2]oct-3-ilo, que está eventualmente sustituido en el átomo de nitrógeno con un resto seleccionado del grupo de alquilo C1-C4, bencilo u oxi; A significa oxígeno o azufre; el anillo B significa benzo o pirido, que están eventualmente sustituidos con restos del grupo de halógeno, ciano, formilo, trifluorometilo, trifluorometoxi, nitro, amino, alquilo C1-C6 y alcoxi C1-C6; E significa C=C, arilo y heteroarilo, pudiendo estar el arilo y heteroarilo sustituidos con restos del grupo de halógeno, ciano, trifluorometilo, trifluorometoxi, nitro, amino, alcoxi C1-C6 y alquilo C1-C6; así como los solvatos, sales y solvatos de las sales de estos compuestos.
Patent EC-SP088389-A (EC)
Title: Formulas de infantes que contiene acido docosahexaenoico y luteína
Inventor: BARRETT-REIS BRIDGET
IPC: A23L33/00
Filed: 2008-04-21
Abstract: El presente invento está dirigido a las formulas para bebes que incluyen grasa, proteína, carbohidrato, vitaminas, y minerales, incluyendo el ácido docosahexaenoico y por lo menos aproximadamente 50 mcg/litro de luteína, donde la relación de peso de la luteína (mcg) con el ácido docosahexaenoico (mg) es de aproximadamente 1:2 a aproximadamente 10:1. El presente invento se dirige también a los métodos que utilizan las formulas para promover la salud retinal y el desarrollo de la visión en los bebes, incluyendo la reducción del riesgo de retinopatía o condición de prematuros en los bebes, y protegerlos contra efectos dañinos de luz natural o artificial excesiva en los ojos de los bebes.
Patent EC-SP088441-A (EC)
Title: Derivados de pirazolo [4,3-d]pirimidin-5-il usados como inhibidores de pde5
Inventor: TOLLEFSON MICHAEL B
IPC: C07D487/04
Filed: 2008-05-08
Abstract: La presente invención comprende el ácido 1-(1-(2-etoxietil)-3-etil-7-4(4-metilpiridin-2-ilamino)-1H-pirazolo[4,3-d]pirimidin-5-il)piperidina-4-carboxilico y sus sales. La invención además comprende las composiciones farmacéuticas, los procedimientos de tratamiento, y los procedimientos de síntesis que se refieren al ácido 1-(1-(2-etoxietil)-3-etil-7-(4-metilpiridin-2-ilamino)-1H-pirazolo [4,3-d]pirimidin-5-il)piperidina-4-carboxilico y sus sales.
Patent EC-SP088914-A (EC)
Title: Bioplaguicidas
Inventor: ZEDDAM JEAN-LOUIS
IPC: A01N63/00
Filed: 2008-11-27
Abstract: Un primer objeto de la invención refiere a una formulación bioplaguicida sólida constituida por volúmenes pequeños de agua, concentraciones altas de larvas de polilla enfermas conteniendo el virus entomopatógeno que específicamente es la cepa JLZ9F del granulovirus de Phthorimaea operculella (PhopGV) y calcita. Este bioplaguicida es útil para el control simultaneo de dos especies de polillas de la papa: Phthorimaea operculella y Tecia solanivora. Un segundo y tercer objeto de la invención refieren al procedimiento de obtención del bioplaguicida, selección/caracterización y aislamiento de cepas del virus entomopatógeno JLZ9F siguiendo pasos o etapas propias de esta invención, tal como se lo describe en la memoria descriptiva.
Patent EC-SP109857-A (EC)
Title: Corriente oscilante de fluido en un orificio de pozo
Inventor: SCHULTZ ROGER L
IPC: E21B28/00
Filed: 2010-01-06
Abstract: Un sistema 100 para hacer oscilar un fluido compresible de trabajo en un orificio de pozo 102 definido en una formación subterránea, incluye una fuente 116 de fluido y un dispositivo 204 para hacer oscilar a este último. La fuente 116 de fluido envía al fluido compresible de trabajo hacia un conducto 106 dispuesto dentro del orificio de pozo 102. El dispositivo 204 para hacer oscilar al fluido está configurado para descansar en el orificio de pozo 102. El dispositivo 204 para hacer oscilar al fluido incluye una superficie interna que define un espacio interno de dicho dispositivo 104, una entrada 310 hacia el espacio interno y una salida 314 desde el espacio interno. La superficie interna permanece estática durante la operación para recibir al fluido compresible de trabajo en el espacio interno a través de la entrada 310 y para variar con el paso del tiempo el caudal de flujo de dicho fluido compresible desde el espacio interno a través de la salida 314
Patent EC-SP961942-A (EC)
Title: Producto de confiteria
Inventor: JURY MARK
IPC: A23G1/00
Filed: 1996-11-19
Abstract: Un producto de confitería que comprende chocolate o un material de confitería que contiene grasa junto con un componente de dulce masticableque tiene una base de un jarabe continuo que comprende una solución de azúcares, sustitutos del azúcar y/o jarabes de glucosa en agua, caracterizado en que el producto de confitería comprende una matriz de chocolate que tiene dispersadas venas o hilos de dulce masticables.
Patent FI-20021661-A (FI)
Inventor: GURTOV ANDREI
IPC: H04L12/54
Filed: 2002-09-17
Abstract: The invention relates to a terminal equipment (1) configured to run simultaneously at least two applications with respective connections via a common communication link, and a user interface (3, 4). In order to avoid excessive buffering and congestions said terminal equipment (1): is responsive to information indicating priorities of said applications fed to the terminal equipment (1 ) via said user interface (3, 4), comprises a congestion manager (5) configured to allocate a portion of the capacity of said communication link to each of said connections, the size of the portion allocated to the respective connections depending on the priorities of the applications, and is configured to adjust the traffic of the respective connections according to the portion of the communication link allocated to the connections. <IMAGE>
Patent FR-1176107-A (FR)
IPC: B64D45/00
Filed: 1955-10-04
Granted: 1959-04-07
Abstract: 816,779. Measuring acceleration electrically. GENERAL ELECTRIC CO. Sept. 29, 1955 [Oct. 4, 1954], No. 27752/55. Class 40 (1). [Also in Group XIX] In an acceleration responsive device comprising a container rotatably supported about an axis other than one passing through its centre of mass so that linear accelerations transverse to the plane containing the axis and centre of mass apply a torque to the container, and means for applying a counter torque in response thereto, the container is suspended in a liquid, the density of which is such that the upthrust thereof is equal to the weight of the container and its contents. In the embodiment the casing 10 incorporating an unbalance mass 15 is pivoted in bearing means 11 in a housing 12 fixed to the vehicle, the acceleration of which is to be measured. Angular displacement of the casing in response to accelerations normal to the plane of the drawing results in displacement of coil 21 in the air gap of the magnetic circuit 22, 23. The signal thus generated in the coil after amplification at 27 (Fig. 2) is applied to the control winding 16 of a two-phase motor, the rotor 17 of which together with flywheel 18 is freely pivoted in bearings 20. The motor energization is such that the reaction torque on the casing balances the accelerating torque to restore it to a null position. The torque on the rotor, which is therefore proportional to vehicle acceleration accelerates it proportionally so that at any instant rotor speed is proportional to vehicle speed, and, integrated angular displacement to distance travelled. The motor drives rotor 41 of a selsyn transmitter 42, the output of which, operates indicating or control mechanism. The wiring shown in Fig. 2 is omitted from Fig. 1 for clarity. Housing, 12 is filled with a low viscosity liquid, e.g.. heptacosafluorotributylamine of such density relative to the mass of casing 10 and its contents, and the distribution of mass in the casing is such that bearings 11 are unloaded except for acceleration along the rotation axis, when they provide a balancing torque.
Patent FR-1558383-A (FR)
IPC: B29C65/08
Filed: 1967-11-24
Granted: 1969-02-28
Abstract: 1,200,305. Compression moulding. W. R. GRACE & CO. 23 Nov., 1967 [24 Nov., 1966], No. 52738/66. Heading B5A. [Also in Division B6] A method of shaping thermoplastic material includes the step of pressing an ultrasonicallyvibrated tool against the material to soften it, the material being simultaneously shaped by the tool itself or by a subsequent compression step using the tool itself or a non-vibrated, preferably cooled, tool. Articles may be moulded from blanks by this method or the surface configuration of already existing articles modified. In the embodiment, illustrated in the Figure, a blank to be shaped is moved upwardly into co-operation with a stationary ultrasonically vibrated shaping tool 29, 30, by a platform 32 actuated by a piston 34. The tool is vibrated through a velocity transformer 27 by means of a magnetostrictive or piezo-electric device 26 located in a cooling bath 23, and may be itself cooled by a conduit 30. In an alternative embodiment (see Fig. 2, not shown) a blank is located in a crown cap and is compressed to a liner by a reciprocable upper vibrated tool. The above method and apparatus is particularly useful with thermoplastic polymers such as butyl rubber, an ethylene-vinyl acetate copolymer, low density polyethylene or a mixture of these. Alternatively plasticized P.V.C., rigid P.V.C. or polymethyl-methacrylate may be used.
Patent FR-1600835-A (FR)
Title: Cpds. R1=H or 1,2-CH2- R2=3-keto DELTA4, 3-Keto DELTA1,4, 3-keto-DELTA4,6 3-keto-DELTA1,4,6, 3-OR-DELTA4, 3-OR-DELTA4,6, 3-OR-DELTA3,5, or 3-OR'-DEL
IPC: C07J5/00
Filed: 1968-07-10
Granted: 1970-08-03
Abstract: Cpds. R1=H or 1,2-CH2- R2=3-keto DELTA4, 3-Keto DELTA1,4, 3-keto-DELTA4,6 3-keto-DELTA1,4,6, 3-OR-DELTA4, 3-OR-DELTA4,6, 3-OR-DELTA3,5, or 3-OR'-DELTA2,4,6 where R=H, alkyl, or acyl, and R1=alkyl or acyl; R3=H, halogen, or (1-6C) alkyl R4=H or 6,7-CH2- R5=H, OH, Oalkyl, or Oacyl R6=MeCO, -CO.CH2OH opt. esterified or acylated, or -CH(OH)Me R7=(2-3C) alkyl or (2-3C) alkenyl R8=3-keto-DELTA4, 3-keto-DELTA1,4, or 3-keto-DELTA1,4,6 (I)-Gestagens (esp. R7=Et), contraceptives, and pregnancy-maintaining cpds. (II)-Intermediates for (I).
Patent GB-1047371-A (GB)
IPC: B65D5/355
Abstract: 1,047,371. Cartons. RIEGEL PAPER CORPORATION. April 28, 1965 [July 6, 1964], No. 17914/65. Heading B8P. A condensable carton 10 made from a blank comprises an upper portion 8 and a lower portion 9 connected by bellows panels 32, 33, 37, 38. The ends of the carton have closure flaps 50, 52 &c. and may have dust flaps secured to the side walls 11, 13. In an alternative embodiment, bellows panels are not provided on the side walls 13, 11, Fig. 6 (not shown), but a U-shaped liner 61, 62, 63, Figs. 7, 8 (not shown), is provided which keeps the upper and lower portions in alignment. To remove the contents C from the carton, the carton is condensed by bringing the body portions 8, 9 together. The carton may be wrapped in a transparent plastics sheet, or a window and the openings in the bellows may be covered with said material.
Patent GB-1050350-A (GB)
IPC: B04C5/12
Abstract: 1,050,350. Hydrocyclones. BLACK CLAWSON CO. March 3, 1964 [March 5, 1963], No. 8972/64. Heading B2P. A hydrocyclone for cleaning cellulose suspensions comprises a substantially vertical shell 13, 20 having a rejects outlet at its lower end, a tubular vortex finder 30 defining the outlet for accepted stock, a tangential inlet 22 for stock to be cleaned, a perforate screen 40 covering the lower end of the vortex finder 30 for preventing entry thereto of larger particles, such as knots, shives etc., and a rotor 44 supported for movement in sweeping relation with the lower surface of the screen 40 for causing the particles too large to pass therethrough to be discharged into the spiral flow of feed stock descending from the annular space between the shell 13, 20 and the vortex finder 30. The rotor 44 is mounted on a shaft 42 coupled to the output shaft of a gear reduction unit 60, Fig. 2 (not shown), driven at the same or slightly higher speed than the spiralling rate of the accepted stock via belt and variable speed drive pulley by a motor 50 adjustably mounted on a bracket 52. Alternatively the rotor shaft is directly connected to the motor. The rotor has blades 45 each of which, Figs. 6 and 7 (not shown), has a leading edge 46 which is offset in the direction of rotation of the rotor to create the sweeping action relative to the screen surface and which is inclined toward the screen to generate a pressure wave tend to force material through the screen. In addition each blade is relieved at 48 behind a flat portion 47 to create a low pressure wave tending to lift material away from the screen surface. In modifications, Figs. 8 and 9 (not shown) the screen is tapered outwardly or inwardly and the rotor is correspondingly shaped. The shaft 75, Fig. 11 (not shown), supporting the impeller may be hollow for the application of suction for removing air from the accepted stock or for removing a lighter fraction of the accepted stock which is normally discharged through an outlet 35. The rejects are discharged through a chamber 15 intermittently or periodically through the action of control valves 17, 18. A valve 19 provides for addition of liquid during and after discharge to prevent air from entering the shell 13, 20. Elutriation water is introduced at 21.
Patent GB-1053549-A (GB)
IPC: C13K1/08
Abstract: 1,053,549. Starch conversion product. A. E. STALEY MANUFACTURING CO. June 12, 1963 [June 21, 1962], No. 23465/63. Heading C2C. A dehydrated starch conversion product is obtained by evaporating water from and dehydrating a concentrated aqueous starch conversion liquor having a dextrose content of at least 86% until the moisture content is less than 5% by heating it to a temperature of 130- 285‹ F. under vacuum and under turbulent flow conditions so that a molten dextrose glass is formed, kneading the molten glass and then rapidly cooling it to a temperature below 150‹ F. to induce crystallization and to increase the crystallinity to at least 45%, the kneading being performed at 150-285‹ F. for a period of 0À5-25 mins. If desired, the crystallization may be carried out in two stages, the first at 150-250‹ F. and the second at a temperature below 150‹ F. The starch conversion liquor may be obtained by the amyloglucosidase conversion of a thinned starch paste. The starch may be cereal starch, root starch, waxy starch, highamylose corn starch, separated starch fractions, e.g. amylose or amylopectin or modified starch.
Patent GB-1054021-A (GB)
IPC: G03B21/132
Abstract: 1,054,021. Coated glass plates. KOLLSMAN INSTRUMENT CORPORATION. April 25, 1963 [May 18. 1962], No. 16357/63. Heading B2K. [Also in Divisions G1 and G2]. An opaque slide for use in a data plotting projector (see Division G1) consists of a glass layer with a primary coating of lead or indium, a secondary coating of aluminium, molybdenum or silver and a final coating of magnesium fluoride.
Patent GB-1135898-A (GB)
Abstract: 1,135,898. Quinazoline derivatives. PARKE, DAVIS & CO. 19 July, 1967, No. 33236/67. Addition to 1,104,576. Heading C2C. [Also in Divisions A2 and A5] Novel quinazoline derivatives of the formula and the corresponding di-salts with bases wherein X is hydrogen, methyl or chlorine are prepared by reacting the corresponding C 1-4  alkyl di-esters with acidic or basic hydrolytic agents under mild conditions. Di - ethyl - {p - {[(2,4 - diamine - 6 - quinazolinyl) - methyl] - amino} - benzamido} - malonate is prepared by hydrogenating in the presence of Raney nickel a mixture of diethyl- (p-aminobenzamido)-malonate and 2,4-diamino- 6-quinazoline-aldehyde, obtained by refluxing, in acetic acid, a mixture of p-nitrobenzaldehyde with 2,4 - diamino - 6 - quinazoline - aldehyde, phenylhydrazone, acetate resulting from the hydrogenation of a mixture of 2,4-diamino-6- quinazoline carbonitrile and phenyl hydrazine in acetic acid in the presence of Raney nickel.
Patent GB-1144066-A (GB)
Abstract: 1,144,066. Walking beam conveyers for furnaces. TABOUGNAR A.B. 2 June, 1966 [28 Feb., 1966], No. 24658/66. Heading F4B. In a continuous metal heating furnace of the walking beam type the rate of forward movement of ingots 6 or the like in a preheating zone 1 and a final heating zone 2 is varied by having a fixed hearth of stepped beams higher at 3 in zone 1, the alternate walking beams 4 being raised by rollers 9 on pivoted support arms 10 to different heights whereby work in zone 2 may be moved without moving that in zone 1. The advancing and retracting movement of beams 4 on the rollers 9 is performed by conventional apparatus, e.g. an hydraulic motor. The various beams are provided with longitudinal ribs, Fig. 2 (not shown). In a modification, Fig. 5 (not shown), the fixed beams are level and the walking beams are stepped.
Patent GB-1225637-A (GB)
IPC: H01L29/00
Filed: 1968-05-28
Abstract: 1,225,637. Semi-conductor devices. INSTITUTET FOR HALVLEDARFORSKNING. 28 May, 1968 [29 May, 1967], No. 25379/68. Heading H1K. [Also in Divisions G4-G6] A semi-conductor diode for use as a neutron dosimeter comprises a lightly doped intermediate layer 2, a thin heavily doped layer 1 of one conductivity type on one side of this intermediate layer and a thin heavily doped layer 3 of opposite conductivity on the opposite side of the intermediate layer. The ratio between the width of the intermediate layer and the diffusion length of the carriers in it is greater than 2. Defects in the crystal produced by its exposure to radiation act as recombination centres and decrease the lifetime of the minority carriers thus affecting the diode characteristics in that the forward drop of the diode for a given current is increased in dependence upon the dose received. The semiconductor material used is silicon or germanium with diffused impurities such as zinc or iron to decrease the carrier lifetimes. The intermediate layer is preferably N-type mono-crystalline silicon, deficient in oxygen, and having a donor concentration of less than 5 x 10<SP>14</SP> donors/cm.<SP>3</SP> The sensitivity can be increased by connecting several diodes in series.
Patent GB-1225719-A (GB)
IPC: H01L41/43
Filed: 1969-05-06
Abstract: 1,225,719. Alkaline earth metal salts. W. R. GRACE & CO. 6 May, 1969 [22 May, 1968], No. 23177/69. Heading C1A. . An alkaline earth metal salt of an acid containing a transition metal of Group IVA or VA, in the form of a fine powder, is prepared by forming an intimate mixture of (i) a first component containing one or more alkaline earth metals in combined form, and (ii) a second component containing one or more of the transition metals in combined form, and reacting the mixture to form the salt in a fluid energy mill. Component (i) may be a salt or hydroxide containing an alkaline earth cation, and component (ii) may be a salt or hydroxide, preferably a hydrogel, containing the transition metal component. Examples of (i) include nitrates, acetates, oxalates, carbonates, formates and citrates of, e.g. Ca, Ba or Sr; examples of (ii) include TiO 2  and ZrO 2  hydrogels. The compounds may be fed to the mill in the form of a solution, slurry, paste or powder; and the fluid energy mill is operated at a temperature from 500 to. 1500 F. Decomposable compounds of the rare earths Nb, Ca, Mg, Sn, Ta and La may be fed to the mill to modify the properties of the products and the finepowder product may be processed by calcining, shaping, and sintering. In the examples, the products were: BaTiO 3 ; BaTiO 3  impregnated with CaZrO 3 , or BaZrO 3 ; SrTiO 3 ; and a composition of 0.927 BaTiO 3 , 0.07 CaZrO 3 , 0-003 Nb 2 O 3 .
Patent GB-1226147-A (GB)
IPC: H01B3/30
Filed: 1968-09-23
Abstract: 1,226,147. Polyesterimide/phenolic resin compositions. GENERAL ELECTRIC CO. 23 Sept., 1968 [29 Jan., 1968], No. 45190/68. Heading C3R. [Also in Division H1] A wire-coating composition comprises (a) a polyesterimide prepared from 2À01 parts by weight of ethylene glycol, 8À57 parts by weight of dimethyl terephthalate, 3À74 parts by weight of bis-(aminophenyl)methane, 7À27 parts by weight of trimellitic anhydride and 10À98 parts by weight of tris-(2-hydroxyethyl) isocyanurate, (b) 1À01 parts by weight of a titanate ester, (c) 1À73 parts by weight of a polyisocyanate, (d) 1À75 parts by weight of a phenol-formaldehyde resin and (e) 0À1-0À5 weight per cent of elemental or chemically combined Ce, Co, Mn, Zn, Fe, Pb or Zr. The polyesterimide may be prepared in a solvent. The titanate ester may be of formula Ti(OR) 4  where R is aliphatic, cycloaliphatic, aryl, aralkyl or alkaryl. The metal may be in the form of a soap, e.g. Zn naphthenate, Mn naphthenate, Co naphthenate, Fe naphthenate or Pb octoate. In an example the composition is applied to copper magnet wire and crosslinked by heating.
Patent GB-1228118-A (GB)
IPC: B41J5/18
Filed: 1969-12-17
Abstract: 1,228,118. Selective printing. INTERNATIONAL BUSINESS MACHINES CORP. 17 Dec., 1969 [15 Jan., 1969], No. 61417/69. Heading B6F. Means to prevent repeat actuation.-An actuator 20 selected by a selected key 12 which is driven to the right by a fluted drive shaft, may be returned after actuating the required bails (26) by a spring 34 even if the key is held depressed. The actuator is mounted in V slots 38, 39 and the spring, as well as returning the actuator longitudinally also axially biases it against surfaces 36, 37 so that if a leading edge 28 engages a still depressed key-lever it is cammed away by the surface 19 on the key. Alternatively, the cam may be on the part with the leading edge 28.