baber/WOPTO huggingface dataset:
Patent DE-69226448-D1 (DE)
Inventor: KOTHS KIRSTON
IPC: A61P37/00
Filed: 1992-10-15
Granted: 1998-09-03
Abstract: A purified glycoprotein complex of over 1200 kD apparent native molecular weight having a sedimentation value of approximately 25S and having the ability to selectively bind human Mac-2 or interfere with PHA activation of lymphocytes, DNA sequences that encode the protein, and expression systems for expressing it, thus providing for medicaments that are useful for treating or diagnosing diseases, including cancer, infectious disease, and diseases of the immune system.
Patent DE-69231801-D1 (DE)
Inventor: YANAGISAWA HIROAKI
IPC: A61K/
Filed: 1992-02-21
Granted: 2001-05-31
Abstract: N-Phenylbenzyl imidazole derivs. of formula (I) and their pharmaceutically acceptable salts and esters are new. In (I), R1 = 1-6C alkyl or 3-6C alkenyl; R2 and R3 = H, 1-6C alkyl, 3-6C alkenyl, 3-10C cycloalkyl (opt. polycyclic), aryl(1-6C)alkyl, aryl or aryl fused to 3-10C cycloalkyl; R4 = H, 1-6C alkyl, 1-6C alkanoyl (opt. substd. by one or more halo or 1-6C alkoxy if other than formyl), 3-6C alkenoyl, arylcarbonyl, 1-6C alkoxycarbonyl, tetrahydropyranyl, tetrahydrothiopyranyl, tetrahydrothienyl or tetrahydrofuryl (these 4 opt. substd. by one or more halo or 1-6C alkoxy), SiRaRbRc, 1-6C alkoxymethyl, 1-6C alkoxy(1-6C)alkoxymethyl, halo(1-6C)alkoxymethyl, 1-6C alkyl substd. by at least one aryl, or 1-6C alkanoyl-oxymethoxycarbonyl; Ra, Rb and Rc = 1-6C alkyl or aryl, but not all aryl; R5 = COOH or CONR8R9; R8 and R9 = H, 1-6C alkyl (opt. substd. by at least one (a)) or together are 2-6C alkylene opt. substd. by at least one COOH or alkoxycarbonyl; R6 = H, 1-6C alkyl or alkoxy, or halo; R7 = COOH or tetrazol-5-yl; (a) = aryl, 5-6 membered heterocyclic with 1-4 N, O and/or S, halo, OH, 1-6C alkoxy, COOH, 1-6C alkoxycarbonyl, NH2 or acylamino (acyl = 1-6C alkanoyl or arylcarbonyl); aryl = 6-14C aromatic carbocyclic gp. opt. substd. by at least one of NO2, CN, halo, 6-10C carbocyclic aryl (unsubstd.), 1-6C alkyl or alkoxy, COOH, 1-6C alkoxy-carbonyl, or 1-3C alkylenedioxy or alkylidenedioxy. 23 Cpds. e.g. pivaloyloxymethyl (or (5-methyl-2-oxo -1,3-dioxolen-4-yl)methyl) 4-(1-hydroxy-1-methylethyl) -2-(ethyl, propyl or butyl)-1-(4-(2-tetrazol -5-yl)phenyl)phenyl)methylimidazole -5-carboxylate.
Patent DE-69232197-D1 (DE)
Inventor: VAN HEUVEL MARGARETHA
IPC: A23K20/189
Filed: 1992-03-20
Granted: 2001-12-20
Abstract: The present invention provides the cloning and expression of purified and isolated DNA molecules, obtainable from fungi, which encode enzymes having arabinan-degrading activity. The present invention also provides DNA constructs containing these DNA molecules and methods for their enhanced expression in selected microbial host cells. The present invention further provides methods for the use of the thus-produced arabinan-degrading enzymes.
Patent DE-69310524-D1 (DE)
Inventor: DE LOMBAERT STEPHANE
IPC: C07F9/40
Filed: 1993-08-24
Granted: 1997-06-12
Abstract: The present invention relates to the N-phosphonomethyl substituted tetrazole derivatives of formula (I) and tautomers thereof wherein R0 represents (i) a group of formula (Ia) or (ii) a group of formula -X-COR3 (Ib); R and R' represent independently hydrogen, carbocyclic aryl, 6-tetrahydronaphthyl, 5-indanyl, (alpha)-(trichloromethyl, carboxyl, esterified carboxyl or amidated carboxyl) substituted-(lower alkyl or aryl-lower alkyl), acyloxymethyl optionally monosubstituted on methyl carbon by lower alkyl, by C5-C7-cycloalkyl, by aryl or by aryl-lower alkyl; R1 represents phenyl, or phenyl substituted by lower alkyl, lower alkoxy, halogen or trifluoromethyl; or R1 represents thienyl or furanyl optionally substituted by lower alkyl; or R1 represents hydrogen, if R0 represents a group of formula (Ia); R2 and R4 represent hydrogen, lower alkyl, hydroxy, lower alkoxy, halogen or trifluoromethyl; n is 0, 1 or 2; COR3 carboxyl or carboxyl derivatized in form of a pharmaceutically acceptable ester; X represents a direct bond, C1-4-alkylene or C2-4-alkenylene; and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising said compounds; methods for preparation of said compounds and for the preparation of intermediates; and methods of treating disorders in mammals which are responsive to the inhibition of neutral endopeptidases by administration of said compounds to mammals in need of such treatment.
Patent DE-69323422-D1 (DE)
Inventor: MACARTHUR-ONSLOW ROHAN JAMES
IPC: A47G21/06
Filed: 1993-03-16
Granted: 1999-03-18
Abstract: A foldable eating utensil includes an elongate handle member having a food-engaging blade extending integrally from one end thereof when operatively disposed, the blade being hingedly connected about a transverse axis to the inner edge of a connector plate of the handle member extending laterally between spaced handle arms of the handle member which define therebetween an opening to receive the blade to lie coplanar with the handle member when the blade is hinged to storage disposition, the blade including a longitudinally extending neck portion at its hinged connection to the connector plate and adapted to lie against the connector plate when operatively disposed, the handle arms being foldable each about a lengthwise axis adjacent the connector plate, and the parts being so made and arranged that when the blade has been hinged to operative disposition, the handle arms may be folded digitally towards each other and brought to and held in co-acting relationship in which parts of the handle member engage the blade at its neck portion in such manner as to restrain the blade against movement away from operative disposition.
Patent DE-69418495-D1 (DE)
Inventor: ALLAF KARIM
IPC: A23L19/00
Filed: 1994-08-03
Granted: 1999-06-17
Abstract: PCT No. PCT/FR94/00975 Sec. 371 Date Jul. 12, 1996 Sec. 102(e) Date Jul. 12, 1996 PCT Filed Aug. 3, 1994 PCT Pub. No. WO95/04466 PCT Pub. Date Feb. 16, 1995Materials, for example, plant-based food products, are subjected to heat and pressure in a processing enclosure, wherein the pressure is greater than the pressure of the atmosphere. The heated, pressurized materials are then subjected to a pressure-reduction phase during which the pressure in the processing enclosure is reduced at a rate greater than 500 millibars per second and by an amplitude greater than 1 bar. The rapid pressure-reduction phase of the invention contributes to the production of processed materials having a slightly spongy structure that is due to the presence of micro-cavities that promote the recapture of subsequent moisture.
Patent DE-69423366-D1 (DE)
Inventor: DANIELSSON BJOERN
IPC: F23K3/14
Filed: 1994-12-23
Granted: 2000-04-13
Abstract: A stoker for burning solid fuel, comprising a grate (14) which is connected to a fan (21) for supply of combustion air, and feeding means (11, 12) for controlled feeding of fuel from a reservoir (15, 17) to the grate (14). The reservoir on one hand comprises a primary container (15) located at the feeding means (11, 12) containing a smaller volume of the fuel, and on the other a secondary container (17) which is connected to the primary container and is located at a distance from said primary container and having a main volume of the fuel. The primary container comprises detector means (20a) for controlling replenishment of fuel from the secondary container to the primary container. An air distribution chamber (20b) is located between the grate (14) and the primary container (15), which chamber is supplied with air via the fan (21) distributing air to the grate bowl (14) via a primary air pipe (22), and to the upper side of the grate via a secondary air outlet (23). An outer ring (26) is rotatably journalled upon the upper edge of the grate bowl, and is provided with gear segments to rotate the ring (26) in order to avoid accumulation of cinders at the opening of the grate.
Patent DE-69427195-D1 (DE)
Inventor: CARNEY F
IPC: E01F15/14
Filed: 1994-09-08
Granted: 2001-06-13
Abstract: A crash impact attenuator including one or more cylinders, each bolted or otherwise connected to the adjacent cylinder and such cylinders being connected to the platform of a service vehicle or to an abutment adjacent a highway wherein the cylinders are constructed from a high molecular weight/high density polyethylene material.
Patent DE-69433923-D1 (DE)
Inventor: SEQUEIRA JOEL A
IPC: A61K9/06
Filed: 1994-12-19
Granted: 2004-09-02
Abstract: A pharmaceutical composition for topical treatment of psoriasis and other hyperkeratotic and/or scaly dermatoses containing mometasone furoate (0,1 %) and salicylic acid (5 %) in a pharmaceutically acceptable vehicle and a method of using the pharmaceutical composition to treat psoriasis and hyperkeratotic scaly dermatoses are disclosed.
Patent DE-69509832-D1 (DE)
Inventor: DUPONT SERGE
IPC: B29K23/00
Filed: 1995-07-12
Granted: 1999-07-01
Abstract: A composite article comprises an injected hollow body or a solid body based on a plastic material (A), reinforced by (a) a bundle of continuous reinforcing fibres coiled outside the surface, perpendicular to the axis, and (b) reinforcing fibres dispersed in the body, parallel to the axis. Also claimed is the mfr. of above composite article.
Patent DE-69516415-D1 (DE)
Inventor: BRAMAN C
IPC: C12Q1/6816
Filed: 1995-10-13
Granted: 2000-05-25
Abstract: The invention provides various porphyrin labeled compounds and reagents for labeling molecules with porphyrins. The porphyrin labeled compounds include porphyrin labeled nucleosides, nucleotides, polynucleotides and the like. The porphyrin labeled compounds of the invention are designed so that the porphyrin moiety on the labeled compound may be detected on the basis of a reaction product produced by the porphyrin catalyzed oxidation of a porphyrin detection reagent. The oxidation of the porphyrin detection reagent may result in the formation of light, i.e., a chemiluminescent reaction, or a colored compound, i.e., a colorimetric reaction. The compounds of the invention contain the general structure of: porphyrin-linker-base-sugar-(phos)n-OH. Another aspect of the invention is to provide methods of labeling and detecting polynucleotides by incorporating a porphyrin-labeled nucleotide into a polynucleotide.
Patent DE-69519345-D1 (DE)
Inventor: PASQUALE CARMELO DE
IPC: A61B5/103
Filed: 1995-07-26
Granted: 2000-12-14
Abstract: This invention concerns an appliance for the diagnosis and treatment of scoliosis comprising a supporting base (1) sustaining a polarised light screen (2) at one end, positioned vertically at the back of a seat (3), and a supporting frame (4) at the other end, sustaining a monitor (5) facing the seat (3); the back of the screen (2) being equipped with a closed circuit camera (7) connected to the above monitor (5); a pair of handles (8) being applied to the uprights of the supporting frame (4) as well as handlebars (9) having horisontal axis positioned opposite the seat. <MATH>
Patent DE-69519350-D1 (DE)
Inventor: YAMAMOTO AKIRA
IPC: G06F12/08
Filed: 1995-08-17
Granted: 2000-12-14
Abstract: A method for controlling a disk control apparatus allows to reduce the number of times to read out information necessary for creating a new value of a parity record from a disk unit and the number of times to write the new value of the parity record into a disk unit. A parity-generation scheduling unit employed in the disk control apparatus reallocates data records in an unallocated status to a logical record in the parity group determined to undergo parity generation, to a logical record allocated to a data record pertaining to a parity group other than the parity group determined to undergo parity generation, if such unallocated data record exist in the parity group determined to undergo parity generation. Later on, the disk control apparatus creates a new value of parity record of the parity group initially determined to undergo parity generation and writes the new value into a disk unit. <IMAGE>
Patent DE-69519524-D1 (DE)
Inventor: DAVIS BRUCE
IPC: H04N7/16
Filed: 1995-10-27
Granted: 2001-01-04
Abstract: A method for determining whether one or more of a plurality of data fields for a plurality of television stations of a database that stores program schedule information for an electronic program guide contains missing or invalid data characterised by: 
allowing a user to select a station from the plurality of stations for verification of at least one of the data fields for the selected station; 
allowing the user to select a time range for the verification of the data fields; 
automatically analysing the data fields for the selected station for errors, wherein the errors are comprised of invalid or missing data; 
listing the detected errors; and 
providing the user with the ability to correct the detected errors.
Patent DE-69608335-D1 (DE)
Inventor: LINDSTROM PAUL R
IPC: C23C16/46
Filed: 1996-02-23
Granted: 2000-06-21
Abstract: A CVD reactor (10) having a thermal source that regulates heat to a semiconductor substrate inside said reactor (10) so as to cause an even distribution of heat across the substrate during processing. In one embodiment the thermal source is in the form of a disk (12) which is parallel and concentric with a substrate wafer (13) being processed, said disk (12) being closely spaced from the wafer (13) to uniformly heat the wafer (13) to a temperature suitable for processing. The thermal source disk (12) is heated by a light source (115) which impinges light on one surface (116) of the disk (12) which is oriented away from the wafer (13) so that the other surface (118) of this disk (12) facing the wafer (13) has a uniformity of temperature thereby effecting uniformity of wafer processing. <IMAGE>
Patent DE-69621143-D1 (DE)
Inventor: GRABOWSKI PAUL PHILIP
IPC: B65D75/34
Filed: 1996-09-10
Granted: 2002-06-13
Abstract: PCT No. PCT/US96/14138 Sec. 371 Date Mar. 12, 1998 Sec. 102(e) Date Mar. 12, 1998 PCT Filed Sep. 10, 1996 PCT Pub. No. WO97/14630 PCT Pub. Date Apr. 24, 1997A blister package (10) is formed of a rupturable substrate (12), a blister layer (11) formed over the rupturable substrate and a medicament (15) contained between the blister layer and the rupturable substrate. The blister package can be opened an give access to the medicament by deforming the blister layer so that it punctures the rupturable substrate and allows the medicament to be removed thereform, without applying directly a mechanical pressure on the medicament. This allows friable tablets to be protected and minimizes the breakage of all types of tablets during the opening of the blister pack.
Patent DE-69702627-D1 (DE)
Inventor: TILSTON MICHAEL WILLIAM
IPC: C08F4/658
Filed: 1997-03-04
Granted: 2000-08-31
Abstract: A process for preparing an ethylene copolymer blend comprising contacting ethylene and at least one alpha-olefin comonomer having 3 to 8 carbon atoms with a transition metal based catalyst system in two fluidized bed reactors connected in series, in the gas phase, under polymerization conditions, with the provisos that:   (a) the first reactor is operated at a temperature at or above the dew point of the mixture of monomers, but no higher than about 5 degrees C above said dew point; (b) the mixture of ethylene copolymer matrix and active catalyst formed in the first reactor in the series is transferred to the second reactor in the series; (c) other than the active catalyst referred to in proviso (b), no additional catalyst is introduced into the second reactor;   (d) in the reactor in which a low melt index copolymer is made   (1) the alpha-olefin is present in a ratio of from 0.01 to 0.4 mol of alpha-olefin per mol of ethylene; and (2) optionally, hydrogen is present in a ratio of from 0.001 to 0.3 mol of hydrogen per mol of ethylene; and     (e) in the reactor in which a high melt index polymer is made:   (1) optionally, alpha-olefin is present in a ratio of from 0.005 to 0.6 mol of alpha-olefin per mol of ethylene; and (2) optionally, hydrogen is present in a ratio of from 0.001 to 3 mols of hydrogen per mol of ethylene. h
Patent DE-69718044-D1 (DE)
Inventor: SCHIESSL G
IPC: B65C9/04
Filed: 1997-10-06
Granted: 2003-01-30
Abstract: A machine for applying outserts to articles such as bottles has a turntable driven about a vertical axis. A glue roller and an outsert dispenser are positioned in that order of turntable rotation adjacent the periphery of the turntable. A circular array of bottle support assemblies are mounted concentric to the turntable axis. A closed loop cam groove positioned below the turntable surrounds its rotational axis. Cam followers in the groove are connected to mechanisms that drive shafts on which the bottle support assemblies are mounted rotationally in response to turntable rotation. The support assemblies have a bottle holder plate on them in which plate there is a cavity for holding the bottle to which an outsert is to be adhered on a given outside wall area. The wall area is held at constant distance from the glue roller and the foremost outsert in the dispenser for all bottle sizes and shapes by having sets of holder plates in which the bottle cavity is off center by a sufficient amount for said wall area to be at the constant distance from the roller and dispenser.
Patent DE-69722779-D1 (DE)
Inventor: KIM SOO
IPC: C07F5/06
Filed: 1997-02-12
Granted: 2003-07-17
Abstract: PCT No. PCT/KR97/00025 Sec. 371 Date Aug. 11, 1998 Sec. 102(e) Date Aug. 11, 1998 PCT Filed Feb. 12, 1997 PCT Pub. No. WO97/29112 PCT Pub. Date Aug. 14, 1997Novel magnesium dialkylaluminum alkoxide derivative represented by Mg[( mu -OR')2AlR2]2 wherein R and R' are each a C1-5 alkyl group and R is not the same as R', preferably magnesium dimethylaluminum isopropoxide, is easily prepared by reacting a trialkylaluminum with an alcohol or an aluminum trialkoxide to obtain a dialkylaluminum alkoxide; reacting the dialkylaluminium alkoxide with an alkali metal alkoxide to obtain an alkali metal dialkylaluminum alkoxide; and reacting the alkali metal dialkylaluminum alkoxide with a magnesium halide. The alkoxide derivative of the present invention can be vaporized at a low temperature, below 70 DEG  C. and, therefore, effectively employed in the CVD process of a magnesium aluminate film.
Patent DE-69735621-D1 (DE)
Inventor: STEENBAKKERS PETRUS GERARDUS A
IPC: A61P37/06
Filed: 1997-12-02
Granted: 2006-05-18
Abstract: The present invention relates to an efficient method of producing monoclonal antibodies against surface antigens of cells and viruses. The method accommodates for antigens which are present in only relatively small amounts, or antigens of which only very small amounts are available or antigens which easily lose their in vivo conformation. Thus the method according to the invention comprises a series of steps, comprising a step in which B-cells from a mammal injected with surface antigen-comprising material are enriched with respect to the relative number of specific B-cells and a step which comprises a small-scale fusion technique.
Patent DE-69738502-D1 (DE)
Inventor: MORIMOTO NORISHIGE
IPC: H04N7/081
Filed: 1997-02-13
Granted: 2008-03-20
Abstract: An objective of the present invention is to provide a method for embedding additional information into a video movie without substantially having an influence on the compression efficiency of the video movie and also without substantially causing degradation of the picture quality. ÄCONSTITUTIONÜ   Specify at least one embedding region in the frame of the video movie for embedding information, and determine a type of interframe prediction of the embedding region in correspondence with information to be embedded by referring to an embedding rule where a content of data to be embedded is caused to correspond to the type of interframe prediction of the embedding region. It is desirable that the frame in which the embedding region exists is a bidirectionally predictive-coded frame. <IMAGE>
Patent DE-69738724-D1 (DE)
Inventor: GERRITSE GIJSBERT
IPC: C12N15/54
Filed: 1997-08-15
Granted: 2008-07-03
Abstract: An expression system is provided which comprises component(s) of a lipase regulation cascade. The lipase regulation cascade as disclosed herein includes a kinase, a DNA binding regulator, a polymerase, a promoter, an upstream activating sequence, and secretion factors. Plasmids and transformed cells are also provided as well as methods of transforming host cells using the plasmids. Further, there is provided a kinase that can regulate the expression of a protein, a DNA binding regulator that can regulate the expression of a protein, a Pseudomonas alcaligenes polymerase, a Pseudomas alcaligenes sigma 54 promoter, a Pseudomonas alcaligenes upstream activating sequence, the Pseudomonas alcaligenes secretion factors XcpP, XcpQ, XcpR, XcpS, XcpT, XcpU, XcpV, XcpW, XcpX, XcpY, XcpZ and the xcp regulators OrfV, OrfX.
Patent DE-69801316-D1 (DE)
Inventor: POROWSKI SYLWESTER
IPC: C30B33/00
Filed: 1998-03-13
Granted: 2001-09-13
Abstract: This method of removal of irregularities and highly defected regions of the surface of crystals and epitaxial layers of GaN and Ga1-x-yAlxInyN characterized by mechano-chemical polishing on the soft polishing pad under pressure in presence of chemical etching agent of water solution of bases of the total concentration above 0.01N in time longer than 10 seconds after which the agent is replaced by the pure water without interruption of the polishing and polishing by at least 1 minute aid subsequent diminution of the load and stopping of the machine and then the polished GaN crystal or GaAlInN epitaxial layer is removed of the polishing machine and dried in the stream of dry nitrogen.
Patent DE-69808853-D1 (DE)
Inventor: HARTENSTEIN LAURENT
IPC: F24F6/02
Filed: 1998-07-15
Granted: 2002-11-28
Abstract: The air humidifier draws air from the cabin (4) and after processing returns it to the cabin. A secondary hot air flow is derived from a hot air stream from the aircraft engine, and this secondary hot air stream is introduced into a boiler (6) enclosing an air-water heat exchanger (17). The boiler is partly filled with water, and generates water vapour in proportion to the flow of hot air. This vapour is mixed at the at the boiler outlet with the hot air stream, and the hot air and vapour mix is injected into the air conditioning circuits of the aircraft.
Patent DE-69822322-D1 (DE)
Inventor: HANSON F
IPC: B23B5/16
Filed: 1998-07-30
Granted: 2004-04-15
Abstract: An apparatus (20) for counterboring a pipe (25) includes an expander unit (24), a shaft (26) extending from the expander unit, a flywheel (30) rotatably and slidably mounted on the shaft, a frame (34) mounted on the flywheel to be movable in a radial direction, a tool mount (50) and a guide wheel mount (52) formed on the frame, the tool mount traveling with the flywheel into the interior of the pipe during counterboring and the guide wheel mount traveling outside of the pipe during counterboring, the guide wheel mount being connected to the tool mount by guide wheel arm (51) having a radial member (54) that is axially offset to the rear of the tool mount by a distance at least the length of the counterbore to be machined in the pipe, a cutting tool (56) adjustably mounted to the tool mount, a guide wheel (72) rotatably mounted on the guide wheel mount, an inward force applying member (116) and an outward force applying member (122) connected between the flywheel and the frame such that the frame can be moved and biased with respect to the flywheel, the radially innermost point of the guide wheel being radially spaced apart from the cutting tool to define the wall thickness of the counterbore to be machined into the pipe.