baber/WOPTO huggingface dataset:
Patent CO-6190550-A2 (CO)
Title: Procedimiento para preparar acido 4- amino-butirico biaril- substituido o derivados del mismo y su uso en la produccuion de inhibidores de endopeptidasa neutra
Inventor: HOOK DAVID
IPC: C07C227/16
Filed: 2009-04-07
Abstract: 1.- Un procedimiento para producir un compuesto de acuerdo con la fórmula (I),o una sal del mismo, en donde R1 y R1´ son independientemente hidrógeno o un grupo protector amina, y R2 es un grupo carboxilo o un grupo éster, que comprende hacer reaccionar un compuesto de acuerdo con la fórmula (ii),o una sal del mismo, en donde R1 y R1' son como se definieron anteriormente, con hidrógeno en presencia de un catalizador de metal de transición y un ligando quiral, en donde el metal de transición se selecciona del grupo 7, 8 ó 9 de la tabla periódica. 2.- Un procedimiento de acuerdo con a reivindicación 1, en donde la reacción se realiza como una catálisis homogénea. 3.- Un procedimiento de acuerdo con la reivindicación 1 ó 2, en donde el catalizador de metal de transición comprende rodio o rutenio. 4.- Un procedimiento de acuerdo con cualquiera de las reivindicaciones precedentes, en donde el catalizador de metal de transición comprende un complejo de dímero, de preferencia un complejo de dímero de rutenio. 5.- Un procedimiento de acuerdo con cualquiera de las reivindicaciones precedentes, en donde el catalizador de metal de transición comprende [Rul2(p-cimeno)]2. 6.- Un procedimiento de acuerdo con cualquiera de las reivindicaciones 1 a 3, en donde e 1 catalizador de metal de transición comprende Rh(nbd)2BF4. 7.- Un procedimiento de acuerdo con cualquiera de las reivindicaciones precedentes, en donde el ligando quiral es una fosfina quiral. 8.- Un procedimiento de acuerdo con cualquiera de las reivindicaciones precedentes, en donde el ligando quiral es un ferroceno quiral.
Patent CO-6210805-A2 (CO)
Title: Metodos para fabricar aerosoles estables de un medicamento con una distribucion de tamaño de particula fino consistente y una fraccion de particula fina
Inventor: SHERWOOD JILL K
IPC: A61K31/58
Filed: 2009-08-06
Abstract: 1.- Un método para la fabricación de un producto farmacológico el cual comprende: a) almacenar un recipiente a una temperatura mayor que las condiciones ambiente por al menos siete días aproximadamente, en donde dicho recipiente comprende una suspensión o solución que comprende por lo menos un agente farmacéutico activo, un propelente seleccionado entre el grupo que consiste de 1,1,1,2-tetrafluoroetano, 1,1,1,2,3,3,3-heptafluoropropano y una combinación de los mismos y de manera opcional, excipientes; y b) llevar a cabo pruebas de liberación en dicho recipiente luego de dicho almacenamiento. 2.- El método de la reivindicación 1, en donde dicho agente farmacéutico activo es parcialmente soluble en etanol. 3.- Un producto farmacológico producido por el método de la reivindicación 1. 4.- El método de la reivindicación 1, en donde dichos excipientes son seleccionados a partir del grupo que consiste de co-solventes, surfactantes, vehículos y combinaciones de dos o más de los mismos. 5.- El método de la reivindicación 1, en donde dichos excipientes son seleccionados a partir grupo que consiste de etanol, ácido oleico, y combinaciones de dos o más de los mismos. 6.- El método según la reivindicación 1, en donde el almacenamiento es por un periodo de tiempo de por lo menos 2 semanas aproximadamente. 7.- El método según la reivindicación 1, en donde el almacenamiento es por un periodo de tiempo de por lo menos 3 semanas aproximadamente. 8.- El método según la reivindicación 1, en donde el almacenamiento es por un periodo de tiempo de por lo menos 4 semanas aproximadamente. 9.- El método según la reivindicación 1, en donde el almacenamiento es por un periodo de tiempo de por lo menos 5 semanas aproximadamente.
Patent CO-6382082-A2 (CO)
Title: Composiciones antimicrobianas
Inventor: LI DANPING
IPC: A01N43/42
Filed: 2011-06-09
Abstract: La presente invención se refiere a composiciones antimicrobianas y más específicamente composiciones de derivados del ácido carboxílico de quinolona. Estas composiciones tienen solubilidad, estabilidad, y tolerabilidad mejorada. Estas composiciones son útiles para la administración intravenosa para tratar, prevenir, o reducir el riesgo de infección.
Patent CO-6602153-A2 (CO)
Title: Produccion de propileno por deshidratacion e isomerizacion del esqueleto simultaneas de isobutanol sobre catalizadores acidos seguidos de metatesis
Inventor: VERMEIREN WALTER
IPC: B01J29/06
Filed: 2012-09-14
Abstract: Procedimiento para la producción de propileno en el que, en una primera etapa, el isobutanol se somete a una deshidratación e isomerización del esqueleto simultáneas para producir olefinas sustancialmente correspondientes, que tienen el mismo número de carbonos y que consisten esencialmente en una mezcla de n-butenos e ¡so-buteno y, en una segunda etapa, los n-butenos se someten a metátesis, comprendiendo dicho procedimiento: a) introducir en un reactor una comente (A) que comprende isobutanol, opcionalmente agua, opcionalmente un componente inerte, b) poner en contacto dicha corriente con un catalizador en dicho reactor en condiciones eficaces para deshidratar e isomerizar el esqueleto de al menos una porción del isobutanol para crear una mezcla de nbutenos e iso-buteno, c) recuperar de dicho reactor una comente (B), retirar el agua, el componente inerte silo hubiera y el isobutanol no convertido silo hubiera y conseguir una mezcla de n-butenos e ¡so-buteno, d) fraccionar dicha mezcla para obtener una comente de n-butenos (N) y retirar la parte esencial de isobuteno opcionalmente reciclado con la (A) al reactor de deshidratación lisomenzación de la etapa b), e) enviar la corriente (N) a un reactor de metátesis y poner en contacto la corriente (N) con un catalizador en dicho reactor de metátesis, opcionalmente en presencia de etileno, en condiciones eficaces para producir propileno, f) recuperar de dicho reactor de metátesis una comente (P) que comprende esencialmente propileno, n-butenos no reaccionados, productos pesados, opcionalmente etileno no reaccionado, g) fraccionar la corriente (P) para recuperar propileno y opcionalmente reciclar los n-butenos no reaccionados y el etileno no reaccionado al reactor de metátesis.
Patent CO-6690785-A2 (CO)
Title: Lámina de acero para contenedores
Inventor: SUZUKI TAKESHI
IPC: C23C28/00
Filed: 2013-04-03
Abstract: El propósito de la presente invención es proporcionar una lámina de acero para contenedores que mantenga excelente resistencia a la corrosión incluso cuando se ha conducido un tratamiento de superficie que emplaza un tratamiento de cromato, y que tiene excelentes calidades de adhesión de película y apariencia. Esta lámina de acero para contenedores tiene, en por lo menos una superficie de la misma, un recubrimiento de conversión química que comprende por lo menos dos recubrimientos seleccionados de un recubrimiento con Zr que contiene zirconio y tiene un contenido de metal de zirconio de 0.1 - 9 mg/m, un recubrimiento de fosfato que contiene ácido fosfórico y tiene un contenido de fósforo de 0.1 - 8 mg/m, y un recubrimiento de resma fenólica que contiene resma fenólica y en una cantidad de 0.5 - 8 mg/men términos de carbono, el porcentaje del área de la superficie de la capa de recubrimiento de conversión química que tiene partículas de un tamaño prescrito es 0.1 - 50%.
Patent CO-6781498-A2 (CO)
Title: Máquina y procedimiento para el teñido de carretes de hilo y/o de fibra textil enrrollada en paquetes
Inventor: BELLINI GIOVANNI
IPC: D06B5/16
Filed: 2013-07-26
Abstract: La presente invención se refiere a una máquina (1) para el teñido de carretes de hilo (8) y/o de fibra textil enrollada en paquetes. La máquina (1) comprende: una estructura (2) que delimita una cámara (3) al menos parcial o completamente llenada con al menos un fluido de teñido (4); medios de soporte (6), en particular, al menos una placa de soporte (6), sumergida en dicho fluido de teñido (4); una pluralidad de varillas de soporte de carrete (7) que se comunican a través del fluido con los medios de soporte (6) para permitir que el fluido de teñido (4) pase entre estas últimas; medios de recirculación (9) para el fluido de teñido (4) asociado a la estructura (2) para iniciar el tránsito del fluido de teñido (4) de acuerdo con al menos una ruta establecida. Los medios de recirculación (9) comprenden un mecanismo de recirculación inicial (10) interpuesto entre la cámara (3) y la placa de soporte (6) para inducir el fluido de teñido (4) a pasar a través de las varillas de soporte de carrete (7). El primer mecanismo de recirculación (10) comprende una bomba (10a) y mecanismos de selección respectivos (12) para dirigir el fluido de teñido a través de los medios de soporte (6), las varillas de soporte de carrete (7) y los carretes respectivos (8), en forma intermitente. Los medios de recircuación (9) comprenden un segundo mecanismo de recirculación (11), para inducir el tránsito del fluido de teñido (4) dentro de la cámara (3) de acuerdo con al menos una ruta cerrada.
Patent CO-6771436-A2 (CO)
Title: Método de preparación de nueva medicina antibacterialde polipéptido recombinante
Inventor: QIU XIAOQING
IPC: C12P21/00
Filed: 2013-09-03
Abstract: La invención suministra un método para preparar una nueva medicina de polipéptido antibacterial recombinante, el cual principalmente se relaciona con la fórmula de medio de cultivo líquido adecuada para la producción a gran escala del polipéptido antibacterial, así como la optimización de los parámetros de cultivo agrandados.
Patent EP-1037310-A2 (EP)
Inventor: WILLINSKI BERND DIPL-ING
IPC: H01R4/24
Filed: 2000-01-25
Abstract: The socket has a longitudinal clamping slot (4). The socket body has two spring limbs with cutting edges converging towards the clamping slot. The cross-section of one of the two sprung limbs (5) is tapered in its elastically deformable region towards the clamping slot. The tapered cross-section extends to the cutting edge of the sprung limb. The reduction in cross-section may be continuous.
Patent EP-1013760-A2 (EP)
Inventor: THEOFAN GEORGIA
IPC: A61P13/12
Filed: 1994-02-02
Abstract: Disclosed are novel bactericidal/permeability-increasing (BPI) protein products
wherein the leucine residue at position 193 is the carboxy terminal residue.
Also disclosed are DNA sequences encoding the BPI protein products, methods
for the production of the same in appropriate host cells, and pharmaceutical
compositions containing the BPI protein products.
Patent EP-1037455-A2 (EP)
Inventor: NEUHAUS RALF
IPC: G06F17/22
Filed: 2000-03-15
Abstract: The system includes a connection to a public telecommunication network. A processor unit with program memory and a number of communication connections for telecommunication terminals are provided. A processing module (A) converts determined and stored data, which are relevant to tariff rate calculation into an HTML format.  A communication module (B) transmits the data provided in the HTML format to an external data processing apparatus (2) via a data interface using the TCP/IP protocol and the HTTP protocol.
Patent EP-1048398-A2 (EP)
Inventor: MCNAMARA JEFFREY S
IPC: B23Q7/00
Filed: 2000-04-14
Abstract: A workpiece transfer apparatus with a shuttle underlying workpieces received
on workstations which is raised and lowered by a lifting mechanism disposed above
the workpieces. The shuttle has a support rail and an indexing rail operably connected
to a drive for advancing and retracting the indexing rail relative to the workstations.
To transfer one or more workpieces from their current workstations to respective
subsequent workstations, the shuttle is raised by the overhead lifting mechanism to
engage the workpieces from underneath and raise the workpieces from their current
workstations. The indexing rail is advanced to position the workpieces above
respective subsequent workstations and the shuttle is lowered to place the workpieces
on these subsequent workstations. Subsequently, the indexing rail is retracted to its
starting position so that the apparatus is ready for the next transfer cycle.
Patent EP-1072362-A2 (EP)
Inventor: BRANDSTETTER JOSEF
IPC: B24D9/02
Filed: 2000-06-08
Abstract: The carrier roll for grinding and polishing elements is a one-piece unit which comprises a ring section (1) and a hub section (2) joined to one another by means of vibration isolating connector sections (3).
Patent EP-1054381-A2 (EP)
IPC: G02F1/1362
Filed: 1994-06-24
Abstract: An active matrix type liquid crystal display system has a pair of substrates (7), signal
electrode lines (2) and scanning electrode lines (1) formed on one of said pair of said
substrates and crossing each other in a matrix form; a plurality of pixels formed by
adjoining said signal electrode lines and said scanning electrode lines; a plurality of
switching elements and a liquid crystal layer interposed between said pair of the
substrates. Each pixel of said pixels includes an electrode structure for generating an
electric field having a component substantially in parallel with one of said pair of
said substrates upon application of at least one predetermined voltage thereto, and an
optical structure for obtaining a voltage vs brightness characteristic where the voltage
(Voff) to obtain a minimum brightness is greater than zero.
Patent EP-1089027-A2 (EP)
Inventor: MUELLER FRITZ
IPC: F16K27/07
Filed: 2000-09-18
Abstract: An angle gearing (22) is located between the floor drain valve (10) and the handwheel (18). The gearing angle is 90 degrees, and its transmission is 1:1. The gearing comprises two conical gears (24,26). One gear (24) is fixed to the handwheel spindle (20) and the other (26) is connected to the valve spindle via a thread (30).
Patent EP-1106886-A2 (EP)
Inventor: WEICHEL RAINER DIPL-ING
IPC: F16B37/08
Filed: 2000-11-10
Abstract: A screw clamp fitting holds two components together e.g. the flanged ends (2,3) of a circlip around a pipe clamp. The fitting consists of a threaded (16) bolt (10) which is inserted through a spring clip (17,18) with an open-sided rectangular cross section. The space surrounding the bolt within the clip chamber is occupied by a block (6) with a conical space around the bolt thread, and a conical spring plug (7) with an internal thread. The fixture is secured by push-insertion of the bolt which expands the two spring clips (17,18,7) allowing the bolt to advance. The bolt is then tightened by a screwdriver.
Patent EP-1037213-A2 (EP)
Inventor: KATO TATSUO
IPC: G11C11/22
Filed: 2000-02-07
Abstract: A ferroelectric memory is provided that can write ROM
data during manufacture , change the data after that,
and restore the rewritten initial data. The ferroelectric
memory device is made up of memory cells (MC) in which ferroelectric
capacitors (C1, C2) are provided, each memory cell including ferroelectric
capacitors each having a different hysteresis characteristic.
The capacitors (C1, C2) having different hysteresis characteristics
are formed in the manufacturing process as ROM data. The initial
ROM data written in the manufacturing process can be restored
and can be recorded as a polarization direction by employing the
difference between the hysteresis characteristics. In
addition, the recorded data can be freely rewritten by a normal
writing method and the recorded data can be maintained even
when the power is OFF. Even after the initial ROM data is changed,
the initial ROM data can be restored or recovered by employing
the above-described different hysteresis characteristic
Patent EP-1026011-A2 (EP)
Inventor: NAKATA HIROSHI
IPC: B60C9/20
Filed: 2000-02-08
Abstract: A heavy duty pneumatic radial tire comprises a carcass ply (13), a
belt (16) disposed outside of the carcass ply in the radial direction and
comprised of two or more belt layers, at least one auxiliary belt layer (18)
disposed in a widthwise central portion of the belt at a width narrower than
that of the belt, and a tread (21), wherein when the tire is mounted onto a
design rim defined in TRA standard and inflated under an internal pressure
corresponding to 10% of an air pressure defined in the TRA standard, a
radius of curvature (Rs) of an outer profile at both side regions (22) of the
tread is made larger than a radius of curvature (Rc) of the outer profile at a
central region (23) of the tread.
Patent EP-1063084-A2 (EP)
Inventor: KARAIWA MASATO
IPC: B29C47/06
Filed: 2000-06-22
Abstract: A laminate comprising a sliding member contacting layer composed of a
resin composition and a substrate layer composed of a thermoplastic olefin elastomer
(A), said laminate being obtainable by co-extruding:
   said resin composition which is the product of melt kneading 100 parts by
weight of a thermoplastic olefin elastomer (A), 10 to 250 parts by weight of an ultra-high-molecular
weight polyolefin (B) (except a powder thereof having a particle
diameter of 1 to 100 µm) having an intrinsic viscosity (η), as measured in a decalin
solvent at 135°C, of 1 to 40 dl/g, and 1 to 300 parts by weight of an inorganic or
organic filler powder (C) having a particle diameter of 1 to 100 µm and optional
additional components in a twin-screw extruder, and   said thermoplastic olefin elastomer (A).
Patent EP-1079072-A2 (EP)
Inventor: CORREIA VICTOR HUGO SILVA
IPC: F01D5/20
Filed: 2000-07-05
Abstract: A turbine blade includes a hollow airfoil having a squealer tip rib (36)
extending outboard from a tip cap (40) enclosing the airfoil. An impingement
baffle (44) is spaced inboard from the tip cap to define a tip plenum (46)
therebetween. Impingement holes (48) extend through the baffle and are
directed at the junction (42) of the rib and cap for impinging a coolant jet
thereagainst.
Patent EP-1087616-A2 (EP)
Inventor: NAGAMINE TAKATOMO
IPC: H04N3/27
Filed: 2000-09-21
Abstract: There can be solved a problem in which a lock range is narrowed
by using an oscillator such as a ceramic having a high Q and a
horizontal deflection frequency generating system compatible with
all horizontal deflection frequencies of a variety of television
systems cannot be formed without difficulty. This system includes a
frequency-fixed oscillator oscillating at a frequency f0
sufficiently higher than a deflection frequency fh in a multi-scan
display, a first counter for counting a clock outputted from said
oscillator in a descending order, a duration in which an integer n
which results from rounding a decimal point of a value obtained by a
division of f0 fh is divided by an integer m smaller than n and
said first counter counts a value k thus obtained k times is set to
one cycle and a duration in which a second counter for counting a
value m times repeats the counting m cycles is set to one period and
thereby generating a deflection frequency fh.
Patent EP-1102488-A2 (EP)
Inventor: KOCHERLAKOTA SITARAMA S
IPC: H04N7/173
Filed: 2000-11-06
Abstract: A method and apparatus for receiving requests for time scheduled media from a
client over the Internet and the delivery of such media programs in a specified
streaming video format to the client is disclosed. In a first embodiment the client
requests the recording of a media program by a delivery device which delivery device
identifies in an e-mail message the storage location of the requested program in the
delivery system. The client then accesses the delivery system via the Internet using the
storage location identity and the delivery system delivers the stored program. In
another embodiment the client requests and receives substantially real time delivery of
a requested media program.
Patent EP-1068884-A2 (EP)
Inventor: POST PETER G
IPC: A63B59/14
Filed: 2000-07-14
Abstract: A fastening mechanism (10) for connecting a sports attachment (12) to a shaft (14) is provided.
The fastening mechanism (10) comprises an aperture (40) formed in the shaft (14). A fastening member
is mounted to the sports attachment with at least a portion of the fastening member
receivable within the aperture. A biasing mechanism (29) biases at least a portion of the
fastening member in the aperture wherein the fastening member is releasably maintained
within the aperture thereby releasably connecting the sports attachment to the shaft.
Patent EP-1031781-A2 (EP)
Inventor: RAMETSTEINER KARL
IPC: F16L47/04
Filed: 2000-02-18
Abstract: A plastic pipe connection to a plastic connector or molded piece, comprising a plastic sealing sleeve (5) compressed by a stronger plastic compression sleeve (6), is new.  A pipe connection, to a piping connector or molded piece, comprises a pipe end receiving nozzle on the connector or molded piece and a pipe end sealing sleeve which is compressed by an axially pushed compression sleeve having a partially conical interior. When the pipe (4) and the connector or molded piece (1) are made of plastic, the sealing and compression sleeves (5, 6) also consist of plastic, the compression sleeve (6) being made of a stronger plastic and being pushed axially preferably by turning relative to the connector or molded piece.
Patent EP-1198247-A2 (EP)
Inventor: NACHT MARIANA
IPC: A61K38/00
Filed: 2000-08-07
Abstract: L'invention concerne des procédés permettant de moduler l'angiogénèse et/ou la prolifération cellulaire endothéliale, en particulier, des applications visant à réduire ou à inhiber l'angiogénèse, la croissance tumorale et la prolifération endothéliale par administration de compositions contenant claudine-7 et ses équivalents biologiques. L'invention porte également sur des compositions et procédés destinés au traitement de troubles associés à l'angiogénèse (par exemple le cancer).
Patent EP-1208115-A2 (EP)
Title: Feline interleukin-12 as an immune stimulant
Inventor: LUTZ HANS
IPC: C12N15/24
Filed: 2000-07-08
Abstract: The invention relates to a feline interleukin-12 (IL-12) as an adjuvant or immune stimulant, both in the vaccination against and therapy of infectious diseases in felids. The invention also relates to methods allowing both sub-units of IL-12 to be expressed in the required quantity ratios.
Patent EP-1344161-A2 (EP)
Inventor: OSTROWALKER JOSHUA
IPC: G06F3/0484
Filed: 2000-12-14
Abstract: A system and method for visually representing overlapping time-based activities, the method being implemented in a small footprint device. A user of a small footprint device may initiate a query to display time based activities for a selected day. The application program may create a list of time based activities which meet selection criteria specified. Non-overlapping groups may be created from the list of time based activities such that all overlapping time based activities may be included in one group. Overlapping time based activities within one group may be visually represented in different columns created on a display screen of a small footprint device. Non-overlapping time based activities within one group may be visually represented in the same column created on a display screen of a small footprint device.
Patent EP-1109060-A2 (EP)
Inventor: BRESLAV JOURI
IPC: G03C1/09
Filed: 1996-11-13
Abstract: The present invention relates to a radiographic silver halide element comprising
a support and at least one silver halide emulsion layer coated on both sides
thereof, wherein said silver halide emulsion layers comprise a silver halide
emulsion manufactured according to a method
comprising a nucleation step, a growing step and a
washing step, wherein a reduction sensitization is performed between said growing
step and said washing step in the presence of a sulfuring agent and a stabilizer.
According to a preferred embodiment a fine grain silver halide emulsion is added
either between the addition of stabilizer and the addition of sulfuring agent or between
the addition of sulfuring agent and the start of reduction sensitization or both.
Patent EP-1134321-A2 (EP)
Inventor: LOBERMEIER HANS
IPC: E03C1/23
Filed: 2001-02-28
Abstract: The valve operating mechanism, for a sanitary installation, has a closure stopper (2) which is pressed by the user in the closed setting against the force of a spring (4). A ratchet lock in the housing (1) holds the closure stopper (2) in the closed position until released by the operating unit (50), as a push button in the side of the housing (1).