baber/WOPTO huggingface dataset:
Patent DO-P2020000250-A (DO)
Title: Compuestos antagonistas de la pcsk9
Inventor: JIAN LIU
IPC: C12N9/64
Filed: 2020-12-17
Abstract: Se describen compuestos de Fórmula I, o una sal de los mismos: Formula I, donde A, B, D, X, R1, R2 y R8 son como se definen en la presente solicitud, compuestos que tienen propiedades para antagonizar PCSK9. También se describen formulaciones farmacéuticas que comprenden los compuestos de Fórmula I o sus sales, y procedimientos para la fabricación de medicamentos útiles para tratar enfermedades cardiovasculares y condiciones relacionadas con la actividad de PCSK9, por ejemplo, aterosclerosis, hipercolesterolemia, enfermedad cardíaca coronaria, síndrome metabólico, síndrome coronario agudo o enfermedad cardiovascular relacionada y condiciones cardiometabólicas.
Patent DO-P2021000142-A (DO)
Title: Broca cortadora potente
Inventor: JOHN JAMES HERMAN
IPC: E21B10/16
Filed: 2021-06-30
Abstract: Una broca incluye un cuerpo de broca; una pluralidad de cortadores de ranurado montados de manera giratoria en el cuerpo de la broca para definir un primer perfil; y una pluralidad de cortadores de ranurado montados de manera no giratoria en el cuerpo de la broca para definir un segundo perfil. El primer perfil está longitudinalmente por delante del segundo perfil en una dirección de perforación de la broca en una distancia seleccionada.
Patent EE-200000570-A (EE)
Inventor: NORDSTROEM JOHAN
IPC: H04M1/60
Filed: 1999-02-03
Abstract: A telephone has a loudspeaker mounted behind an earpiece portion of a housing, a center region of the earpiece portion having at least one central sound opening, through which sound generated by the loudspeaker is emitted. At least one bass sound opening is located in the housing remotely from the central sound opening, and devices are provided for generating sound with enhanced low-frequency characteristics through the bass sound opening.
Patent GB-189700597-A (GB)
Title: An Improvement in Cycles.
Inventor: SLAZENGER ALBERT EGERTON LEGH
Filed: 1897-01-09
Granted: 1897-12-11
Abstract: 597. Slazenger, A. E. L. Jan. 9. Steering-mechanism. -Relates to straightsteering mechanism for cycles. One or more coil springs e are connected to the crown of the fork b on either side at f, and to the diagonal tube d at g. If the wheel is forced out of the straight line, one of the springs is in tension and tends to restore the wheel to the straight line. A modification is shown in which a flat spring is fixed to the steering-stem or fork crown and passes between pins fixed to the frame. Elastic bands or the like may be employed for the same purpose.
Patent GB-189701013-A (GB)
Title: A New or Improved Combination Table and Writing Desk.
Inventor: KUNTZE ALEXANDER
Filed: 1897-01-14
Granted: 1897-02-20
Abstract: 1013. Kuntze, A. Jan. 14. Desks; tables.-The table top a and rail b are hinged, and can be turned down as shown to give access to the desk c. The top may be divided at the centre, and the halves hinged at each side ; the halves can be turned either to a vertical or horizontal position ; in the latter case they form extensions of the table top, Fig. 5. Instead of hinging the rail b, a part of it d may be fixed to the top a<2>.
Patent GB-189709123-A (GB)
Title: Improvements in the Covering of Drawing Cylinders or Rollers for Spinning and Roving Frames.
Inventor: MARGULIES JESAIAS
Filed: 1897-04-09
Granted: 1898-01-29
Abstract: 9123. Margulies, J., and Boehme, A. April 9. Rollers for spinning and roving frames. The rollers are covered with two layers of india-rubber, of which one is white and soft and the other is black and hard. In the case of the back roller, Fig. 1, the soft layer a is inside and the hard one b outside, while the front roller, Fig. 2, has the layer of soft rubber outside, the ends of the inner layer of hard rubber being thickened, as shown, so as to protect the ends of the soft layer from the effects of becoming soiled with lubricating-oil.
Patent GB-189710595-A (GB)
Title: Improvements in and relating to Pneumatic Tyres.
Inventor: TRENCH JOHN TOWNSEND
Filed: 1897-04-28
Granted: 1898-03-05
Abstract: 10,595. Trench, J. T. April 28. Tyres, pneumatic; felloes or rims.-One edge a of the singletube tyre A is formed with beads a<1>, a<2> separated by a flexible strip a<3>, and these fit into grooves in the rim and are held in position by plates D attached to the rim by screws d. The other edge a is made inextensible, and for this purpose may contain a wire C. When it is necessary to detach the tyre, part of the edge a* is pressed well into the rim, as shown in Fig. 2, with the result that the part diametrically opposite is forced over an edge of the rim. In modifications, the strip a' may be hooked or wired to the rim.
Patent GB-189710630-A (GB)
Title: Improvements in Horse Collars.
Inventor: GULLINE HENRY LAWRENCE
Filed: 1897-04-28
Granted: 1897-08-21
Abstract: 10,630. Gulline, H. L. April 28. Collars, neck.-Fig. 4 shows a transverse section of the collar. The forewale, which may serve as the hames, is made of hollow metal bars a flanged at b, c' to enable them to be riveted &c. to the leather body part d. The bars a may be socketed together at their lower ends, and when used as hames carry the hame tugs g, rein rings, &c.
Patent GB-189711856-A (GB)
Title: Method and Means or Apparatus for Making Copies of Drawings, Printed and Written Matter, and the like.
Inventor: ITASSE GUSTAVE
Filed: 1897-05-12
Granted: 1898-05-12
Abstract: 11,856. Itasse, G. May 12. Copying documents &c. ; branding by heat.-Relates to a process for reproducing by transferring impressions made in fatty inks, and drawings made with crayons or the like. A specially-prepared paper is damped with a suitable liquid, and is then laid upon the impression or drawing and pressed so as to obtain a negative, which is damped with a suitable liquid and transferred to the surface upon which the impression or drawing is to be reproduced. Fig. 1 shows an elevation of a machine for preparing the paper by spreading thereon a solution of guncotton in ethylic ether, ethylic alcohol, and castor oil, to which turpentine may be added. Paper x passes from a roll b over an inclined table g and drying-apparatus p, and is wound upon a roll q. The solution is supplied from a receptacle c provided with a discharge pipe d, and is spread by means of a vertically-adjustable scraper h. The liquid used for damping the coating of the specially-prepared paper may consist of a mixture of sulphuric ether and ethylic alcohol, when obtaining a negative, or may consist of this mixture, or a mixture of ether, alcohol, and guncotton when obtaining the final transfer. When a reproduction of the impression or drawing is required to be made upon smooth paper, glass, porcelain, or other smooth surface, turpentine or resin may be added to the coating and damping liquids. When it is unnecessary to transfer the impression or drawing to some special material, a reproduction can be obtained by using instead of the special paper a transparent or translucent substance such as celluloid, tracing-paper, gelatine, or the like, or a film formed of the composition employed in coating the paper. In a modification of the process, the coating-liquid may be spread upon the gummed or pasted side of a gummed &c. paper, which is then used like an ordinary transfer. The process may also be used by workers in pyrography.
Patent GB-189718438-A (GB)
Title: Improved Coil for Electric Instruments.
Inventor: THOMPSON WILLIAM
Filed: 1897-08-09
Granted: 1898-06-25
Abstract: 18,438. Kelvin of Largs, W. Thomson, Baron. Aug. 9. Solenoids to carry strong currents are constructed in either of two ways, to give more uniform fields and occupy less space than usual. In one form, Fig. 1, for very large currents, copper tubes are divided helically from end to end ; they are of such sizes as to fit within one another, with intervening insulation or air spaces ; alternate tubes are cut right and left handed, and connected at opposite ends. In another form, a modification of a construction described in Specification No. 18,035A, A.D. 1888, a coil is made up of radially-slit copper plates, Fig. 5. These are tinned on one side and insulated with thin paper or mica on the other. They are bent somewhat and put together in pairs, half the tinned sides of the two plates being in contact, and each plate passed through the slot of the other. Such pairs are placed on a rod, pressed together by end nuts, and heated until the tinned surfaces unite. The coil thus formed has half as many turns as plates, and may be placed on an insulating-tube. The plates may be circular, as shown, but are preferably rectangular, to provide more cooling-surface.
Patent GB-189726860-A (GB)
Title: Improvements in or relating to the Raising and Lowering of Window Sashes of Cabs and other Vehicles, also applicable to other Windows.
Inventor: GORDON JAMES
Filed: 1897-11-17
Granted: 1898-11-17
Abstract: 26,860. Gordon, J. Nov. 17. Windows, sliding. A forked channel iron B, B', B<3>, D is fitted to the roof of the cab at the sides, and receives rubber rollers G, H on the window frame, which can then be turned into any of the positions 1, 2, 3, 4 shown in dotted lines. The glass is held in a metal frame by wood fillets overlapped by a tapered part of the frame.
Patent GB-189728787-A (GB)
Title: Improvements in Apparatus for Propelling and Controlling Vehicles.
Inventor: EMBLETON CHARLES ANDREW
Filed: 1897-12-06
Granted: 1898-10-08
Abstract: 28,787. Embleton, C. A. Dec. 6. Motor road vehicles. -Relates to driving and steering gear. The ratchet-wheel L, Fig. 1, on the driven axle is engaged by pawls N, 0, carried by levers R and links S, the outer ends of which are jointed to a pendulum lever P. This is coupled by a link G to a pin E adapted to slide in a slotted lever D, which is connected at C to a reciprocating part of the motor. The acting radius of the pin E may be varied from zero to a maximum by means of a lifting-link H and lever I connected up in the manner shown to the handle K. The transmission rods H are also coupled to the brake levers, Fig. 4, so that, when the pin E is in the zero position, the brakes a are thrown on. Two sets of such gear are employed to admit of driving in either direction. The steering hand-wheel h is connected by chain gearing g to a wheel fixed to the bogie ; this also carries a cam f against which bear the ends of levers d coupled to the clutches b these are normally pressed home, to couple the road wheels to the axle, by springs c, but, in turning, the cam f draws the clutch of the inner wheel out of action and allows it to rotate freely.
Patent GB-189802567-A (GB)
Title: Solder and Flux for Aluminium.
Inventor: HAMMOND GRANT
Filed: 1898-02-01
Granted: 1898-05-28
Abstract: 2567. Hammond, G., and Flint, T. Feb. 1. Soldering.-A solder for aluminium consists of 100 parts of an alloy of tin, 20 parts of silver, 10 parts of zinc, and <1>/10 to 6 parts of aluminium. The flux for use with the solder consists of iodine, or an iodide of tin or mercury alone or mixed with a hydrocarbon, such as vaseline.
Patent GB-189802767-A (GB)
Title: A Combined Drawing Table, Desk, Easel, Bracket, and Stand for Use in Art Schools and the like.
Inventor: FISHER JOHN
Filed: 1898-02-03
Granted: 1898-03-05
Abstract: 2767. Fisher, J. Feb. 3. Tables; desks.- The table top A is hinged at the front, and is supported in an inclined position to form a desk or easel by the hinged frame C or the hinged frame D which engage with notches b in battens B. The frame D has a dovetailed sliding bar E with shelf F. The bar E can be used in either of the positions shown in Figs. 5 and 6, and can be used to support a cast, figure, copy, &c. A bracket to support paints &c. is fitted, and notches serve to support a drawing-board.
Patent GB-189803510-A (GB)
Title: Improvements in Sprocket Wheels and Gearing for Cycles and other Machinery.
Inventor: CARY LEWIS CLEAVELAND
Filed: 1898-02-12
Granted: 1899-02-11
Abstract: 3510. Cary, L. C., Conklin, T. H., and Morehead, C. R. Feb. 12. Toothed gearing; chain gearing.-Relates to multiplying-gearing for cycles and machinery. Fig. 1 shows the invention applied to a cycle. The crank axle G carries a spur-wheel J gearing with pinions V carried by short axles mounted in arms S of a frame held stationary by connection with the cycle frame &c. The pinions V are connected to larger pinions V<1> gearing with internal teeth on a ring W free to rotate in a groove in the casing. External teeth on this ring actuate other pinions X mounted in arms T in the fixed frame S, T, which, through connection with larger pinions X<1>, drive internal teeth y<1> on the casing, which forms part of the crank-axle chain-wheel, or, in the case of frontdriving cycles, part of the hub. The casing is carried on ball bearings on a fixed disc, and the gear is enclosed by a front plate E.
Patent GB-189803985-A (GB)
Title: Improvements in Football Boots.
Inventor: MAY JAMES MILLWARD
Filed: 1898-02-17
Granted: 1898-06-11
Abstract: 3985. May, J. M. Feb. 17. Toe-caps for football boots. Fig. 3 shows a crosssection of a hollow-tipped india-rubber toe-capand the method of attachment. The sole is cut awav to fit within the cap, and is cemented and riveted to it. The upper is also cemented, but is further secured by stitching as indicated by dotted lines. The sole is further secured to the cap by the leather bar K.
Patent GB-189809464-A (GB)
Title: Process and Apparatus for Calcining Lime-stone and other Substances and Recovering Valuable By-products.
Inventor: NAEF PAUL
Filed: 1898-04-25
Granted: 1899-04-25
Abstract: 9464. Naef, P. Sept. 25, A.D. 1897, [date claimed under Sec. 103 of Paterets &c. Act, A.D. 1883]. Calcining-kilns; gas-producers. -Relates to a process for calcining limestone and similar substances, for example, limestone for use in smelting- furnaces, and for recovering bye-products, such as cyanides and ammonia, if desired. The fuel is charged by a conveyer 13 to the top of a coking-apparatus 2. Incandescent gases from the blast furnace 1 enter from the tube 7 through a water-cooled damper 8 to an annular channel, from which they enter the apparatus. Steam is passed through openings 17<a>, 17<b> to convert the cyanide into ammonia, which escapes with the heating-gas and tar through the outlet 15. The coke formed is discharged through doors 12 to a storage hopper 16, from which it is carried by a conveyer 17 to the hopper 18. The material to be calcined, such as limestone or cement, is fed from a hopper 21 by a conveyer 22 to the calcining- kiln 3. This kiln receives incandescent gases from the blast furnace 1 by a tube 7, water-cooled damper 9, annular channel 23, and ducts 24. Steam may be introduced below these ducts to convert the cyanide into ammonia. The gases escape through a pipe 15<a>, while the lime &c. falls to the bottom, and passes through doors 24<a> to a hopper 25, from which it is carried by a conveyer 26 to the hopper 18.
Patent GB-189811056-A (GB)
Title: Improvements in Street Sweeping Machines.
Inventor: LANYON SIMON D
Filed: 1898-05-14
Granted: 1898-08-13
Abstract: 11,056. Lanyon, S. D., and Tripp, J. W. May 14. Sweeping-machines.-Fig. 1 shows a side elevation, and Fig. 3 a central longitudinal section of the machine. The endless elevator 16 is arranged inside the casing 6, and its chains pass over sprocket-wheels fixed on the shafts 10 and 13, the former of which is driven directly from the axle 2 by chain gearing. Levers 21 pivoted to the framing support the axle 22<b> of the brush 22, and their front ends are connected and provided with the device 35, 37 for regulating the distance of the brush from the ground. The shaft 22<b> has a pinion 23 gearing with a pinion 24 integral with or attached to the wheel 25, which is driven by a chain 30 from the wheel 29 on the axle 2, a spring pawl 31 and ratchet-wheel 32 being fitted to prevent motion of the brush when the machine is pushed backwards. The screw conveyer 52 arranged in the chamber 8 is driven from the shaft 13 by the gearing shown in Fig. 1. A slotted plate 66 with a roller 67, screw 70, and spring 68 is arranged on the bolt 28 connecting the levers 21 to the plate 27, and serves as a tension adjusting-device for the chain 30. Casings 38, 39, 44, 46, and 50 are fitted to confine the dust to the machine. Sweepings from the brush are delivered by the elevator to the chamber 8, from which the conveyer 52 delivers them through the shoot 62.
Patent GB-189811072-A (GB)
Title: Improvements in and relating to the Casting of Bullets and to Machines therefor.
Inventor: BURGESS WILSON
Filed: 1898-05-14
Granted: 1898-06-18
Abstract: 11,072. Burgess, W. May 14. Casting ; stamping.-In the manufacture of bullets, the metal is pumped from a crucible c<4> into one of the moulds a carried in a disc and surrounded by a water jacket b<4>. The mouth of the mould slides against a stationary plate c, and in rotating is brought opposite a plunger g which compresses the metal and stamps a device such as the maker's name on the base of the bullet. In this position the lever d<2> is acted on by a cam, not shown, which after suddenly squeezing the bullet between the rod d and plunger g ultimately operates d so as to expel the bullet from the mould. When released by the cam, the rod d is drawn back against the stop e<3> by a spring e<2>. The disc is rotated by ratchet mechanism f, f<1>.
Patent GB-189813069-A (GB)
Title: Improvements in Instantaneous Steam Generators.
Inventor: FORBES CHARLES STEWART
Filed: 1898-06-11
Granted: 1899-04-15
Abstract: 13,069. Forbes, Sir C. S. June 11. Instantaneous generators.- Thin tubes of steel or other metal connect two end chambers, each of which is formed of a dished tube-plate and a flat cover as shown, and which may be made of steel or iron plates, or cast in gun metal &c. On the tubes are threaded heatretaining cylinders 11 of aluminium, copper, cast iron, or other suitable metal, and through them pass rods 12 of similar metal held in place by nuts at each end. These nuts bear on washers 8 with portions of their under faces cut away, as shown in Fig. 4, to allow the passage of water and steam. Water is continuously supplied at 17<b>, and steam escapes at 17<c>. The end chambers are held together by tie-rods formed by extensions of the flange bolts. The space between them is enclosed by a double casing 19, which may contain asbestos wool as shown, or be left hollow for the passage of air. Solid, liquid, or gaseous fuel may be used.
Patent GB-189815791-A (GB)
Title: Improved Liquid Fuel-supplying Arrangements for Marine Boiler Furnaces.
Inventor: FLANNERY JAMES FORTESCUE
Filed: 1898-07-19
Granted: 1899-07-19
Abstract: 15,791. Flannery, Sir J. F., and Boyd, W. July 19. Liquid-fuel fittings.-Relates to liquid-fuel supplying arrangements for marine boilers, with the object of enabling liquid fuel to be stored in ballast tanks with, or alternately with, water in such a way as to avoid the risk of accidents arising from the admixture of water with the liquid fuel supplied to the furnace. Two or more sets of supply or settling tanks and fittings are provided for alternate use, the arrangement being such that, while one or more sets are delivering oil to the furnace, the other is receiving oil from the ballast tanks. In this way the oil can be allowed to settle, for the separation of water, either in one of the service tanks or in a settling-tank, before being supplied to the furnace. Various arrangements of tanks and supply fittings are described and illustrated in the Specification. In the arrangement shown in Fig. 2, 1, 1 are ballast tanks, and 2, 2 service tanks. The oil pumps and injectors and their connections are so arranged that, while one of the tanks 2 is being filled from the tanks 1, the other is being used to supply the furnace. Suitable drain pipes and fittings are provided for the withdrawal of water from the service tanks. In the arrangement shown in Fig. 12, a single service tank, shown in dotted lines at 16, is used in connection with a pair of settling-tanks 15, 15<a>, which are alternately filled from the ballast tank 1 and used to fill the service tank.
Patent GB-189818168-A (GB)
Title: Improvements in Casting Ingots.
Inventor: MCDONALD ROBERT ALEXANDER
Filed: 1898-08-23
Granted: 1898-10-08
Abstract: 18,168. McDonald, R. A. Aug. 23. Ingots.-After ingots have been cast in the usual manner, they are removed from the moulds while the inner parts are in a plastic state, and are passed vertically downwards between rolls 2, 4, so as to force inwards the outer parts of the ingots and prevent piping. The rolls may be of the form shown in Fig. 1, or the rolls 2 may be cylindrical, in which case the ingots are cast with longitudinal ribs on the two faces intended to be acted upon by the cylindrical rolls.
Patent GB-189818701-A (GB)
Title: Improvements in or connected with Flower Holders and the like.
Inventor: WEST CHARLES EDWARD
Filed: 1898-09-01
Granted: 1899-07-01
Abstract: 18,701. West, C. E. Sept. 1. Flower holders; stands for table use.-Consists of a tube a, Fig. 4, for holding water into which the split tube b which holds the flowers is inserted. This split tube is screwed at the neck, so that it may be screwed tight into the internal tube. In a modification, the split tube may slide outside the other tube. The holder may also be used for holding fruit.
Patent GB-189819160-A (GB)
Title: Improvements in and relating to the Manufacture of Cacao Butter.
Inventor: RIECK ADOLF CHRISTIAN MAX
Filed: 1898-09-08
Granted: 1899-07-22
Abstract: 19,160. Rieck, A. C. M. Sept. 8. Fats.-Relates to the extraction of cacao butter. The cacao beans are roasted and hulled and then reduced to a coarse-grained mass which is subjected to high pressure in suitable presses.
Patent GB-189822453-A (GB)
Title: Improved Arrangement for Facilitating the Lowering of Life-boats or Ships' Boats and Carrying same on Board Ship.
Inventor: FOURS ARTHUR COMTE DES
Filed: 1898-10-25
Granted: 1899-07-29
Abstract: 22,453. Des Fours, Comte A. Oct. 25. Boats, launching.-Slipways 5 are hinged to the sides of the vessel, and are normally. held in a vertical position by ropes 2, 3. When inboard, the boat is secured in a vertical position to the launching-slip by pins. Its movement during launching is controlled by a rope wound on a brake drum 8. Floats 7 at the end of the slip prevent it from sinking.