baber/WOPTO huggingface dataset:
Patent CN-1221214-A (CN)
Title: 半导体器件生产方法
Inventor: KAZUMI SAITO
IPC: H01L21/3065
Filed: 1998-12-23
Abstract: 半导体器件的生产方法包含如下步骤:在半导体基片上形成绝缘膜,在绝缘膜上形成由导电材料构成的导电薄膜,在导电薄膜上形成由有机材料构成的防反射敷层,在防反射敷层上形成光敏光刻胶膜,通过曝光在光刻胶膜上显影预定的光图像,以形成光刻胶图形,用包含氧气,反应气及惰性气体的混合气的等离子体的干蚀选择的去除防反射敷层,从而形成防反射敷层图形,并用光刻胶图形作为掩膜蚀刻导电薄膜,从而形成电极。
Patent CN-1272268-A (CN)
Title: 无线通信系统中校正测量的往返行程延迟时间的方法和设备
Inventor: ROZANSKI WALTER J
IPC: H04B1/7115
Filed: 1998-09-28
Abstract: 利用通过上行链路通信信号路径(130—132)接收上行链路通信信号(119)和确定哪个射束曾被远端单元(113)利用在时间上对准上行链路通信信号(119)进行在通信系统(100)中往返行程延迟的校正。具体地,基站(101)分析上行链路通信信号(119)和预测远端单元(113)利用作为时间对准的射束。一旦基站(101)已经确定远端单元(113)利用在时间上对准的射束,基站(101)精确地校正往返行程延迟的任何计算。
Patent CN-1282354-A (CN)
Title: 加成交联的硅橡胶混合物、其制备方法和其用途
Inventor: VOIGT T
IPC: C08L83/07
Filed: 1998-10-12
Abstract: 本发明涉及加成交联的硅橡胶、其制备方法和用途。
Patent CN-1301808-A (CN)
Title: 洗用助剂4a沸石的生产工艺
Inventor: DONG JIALU
IPC: C11D3/08
Filed: 1999-12-30
Abstract: 一种4A沸石的生产工艺,它是将膨润土加硫酸处理,得到酸性白土,再将酸性白土加NaOH溶液碱处理,最后,加入铝酸钠溶液,满足Na 2 O:Al 2 O 3 :SiO 2 :H 2 O=(2.5－4.5):(1.8－2.2):l:(100—240)之比,升温至85—100℃晶化即得4A沸石。本发明的优点是利用资源丰富的膨润土为原料,并且废液能回收铝酸钠和硫酸铵。
Patent CN-1317044-A (CN)
Inventor: ZUKER C S
IPC: C12Q1/02
Filed: 1999-07-27
Abstract: 本发明提供了感觉细胞特异性多肽的分离核酸和氨基酸序列，这些多肽的抗体，检测这些核酸和多肽的方法，和筛选感觉细胞特异性多肽的调节剂的方法。
Patent CR-20110114-A (CR)
Title: Derivados de picolinamida como inhibidores de cinasa
Inventor: BURGER MATTHEW T
IPC: A61K31/444
Filed: 2011-03-02
Abstract: se proporcionan nuevos compuestos, composiciones y metodos de inhibición de la integración de la actividad del provirus de la cinasa Maloney (Cinasa PIM) asociada con tumorigénesis en un sujeto humano o animal.
Patent CR-20140369-A (CR)
Title: Composiciones veterinarias orales parasiticidas que comprenden agentes activos de acción sistémica, métodos y usos de las mismas
Inventor: SOLL MARK D
IPC: A61P33/00
Filed: 2014-08-01
Abstract: Composiciones veterinarias orales para combatir ectoparásitos y endoparásitos en animales, que comprenden al menos un agente activo de acción sistémica en combinación con un vehículo farmacéuticamente aceptable. También métodos mejorados para erradicar, controlar y prevenir infecciones e infestaciones por parásitos en un animal que comprende administrar las composiciones de la invención a un animal que lo necesita.
Patent CR-20170571-A (CR)
Title: Nuevos derivados aminoácido, un proceso para su preparación y composiciones farmaceúticas que los contienen.
Inventor: GENESTE OLIVIER
IPC: C07D495/04
Filed: 2016-06-22
Abstract: Compuestos de fórmula (I): en la que R1, R2, R5, R6, R7, R12, X, Y, A, E y n son como se han definido en la descripción.
Patent EC-SP003346-A (EC)
Title: 2 aminopiridinas que contienen sustituyentes de tipo anillo condensado
Inventor: ADAMS LOWE JOHN
IPC: C07D213/73
Filed: 2000-02-10
Abstract: La presente invención se refiere a derivados de 2-aminopiridina de la fórmula I: (gráfico), o sales farmacéuticamente aceptables de los mismos, en la que A y B son cada uno independientemente H, o juntos, A y B forman un anillo condensado al anillo de fenilo, siendo dicho anillo saturado o insaturado y conteniendo de 5 a 7 átomos en el anillo, donde dichos átomos en el anillo pueden opcionalmente comprender de 1 a 2 heteroátomos seleccionados independientemente del grupo constituido por N, O o S, siempre que los miembros de dos anillos adyacentes no sean heteroátomos: X es oxigeno o un enlace sencillo; Y es alquilo (C1-C6); R1 es hidrógeno, alquilo (C1-C6) o un grupo (alquilo C1-C6) sustituido con -NR2R3 en el que R2 y R3 se seleccionan bien independientemente del grupo constituido por H, alquilo, arilo, aralquilo, o tetrahidronaftaleno, siendo dicho grupo arilo o dicho resto arilo de dicho grupo aralquilo fenilo o naftilo, conteniendo dicho grupo alquilo o dicho resto alquilo dedicho grupo aralquilo de uno a seis átomos de carbono y siendo una cadena lineal o ramificada, y estando dicho grupo arilo, dicho tetrahidronaftaleno o dicho resto arilo de dicho grupo aralquilo opcionalmente sustituido con uno a tres restos de halógeno, nitro, ciano, amino, alcoxi (C1-C4) y alquilamino (C1-C4), o bien R2 y R3 forman, junto con el nitrógeno al que están unidos, un anillo heterocíclico, o un anillo cíclico o bicíclico que está saturado o insaturado. Los compuestos de la invención tienen la capacidad de inhibir la actividad de las sintasas de oxido nítrico (NOS), y po lo tanto, son útiles en el tratamiento de enfermedades, estados y transtornos del sistema nervioso central, entre otros.
Patent EC-SP014052-A (EC)
Title: Resinas basadas en fenol-formaldehido hibrido e isocianato, y metodos para producir resinas hibridas endurecidas y el uso de estas resinas hibridas
Inventor: CREEL LEWIS D
IPC: C08L75/04
Filed: 2001-05-02
Abstract: Las resinas híbridas formadas de una resina de fenol-formaldehido acilado (PF) y un componente isocianato tienen una estabilidad de almacenamiento extendida, sin embargo curan a una velocidad mayor que cualquiera de sus componentes cuando se usan en procesos convencionales para fabricar aglomerados, paneles de hebra o de fibra de madera y otros.
Patent EC-SP034466-A (EC)
Title: Farmaceutico novedoso
Inventor: CRAIG ANDREW SIMON
IPC: C07D417/12
Filed: 2003-02-04
Abstract: Un novedoso compuesto farmacéutico L( + ) Tartrato de 5-(4-(2-N-metil-N-(2-piridil)amino)etoxi)bencil)tiazolidin-2,4-diona o un solvato del mismo, un procedimiento para preparar dicho compuesto, una composición farmacéutica que comprende dicho compuesto y el uso de dicho compuesto en medicina.
Patent EG-22640-A (EG)
Title: A device for the preheating of scrap
Inventor: NORTHEMANN RALF
IPC: C21C5/52
Filed: 2000-01-19
Granted: 2003-05-31
Abstract: The aim of the invention is to improve a preheating device for preheating scrap intended for transfer to a metallurgical furnace. To this end the invention provides for a precombustion chamber (4) which is situated at the level of the upper section (8) of the combustion chamber and has at least one first closeable opening (23) leading to the upper section of the combustion chamber and at least one other, second closeable opening (22) for introducing a batch of cold scrap by means of feeding means (5). Each batch can be fully or partly received by the precombustion chamber (4). The invention also provides for means for the controlled modification of the gas, pressure and/or temperature conditions in the precombustion chamber. The openings in said precombustion chamber can be actuated in the manner of a sluice.
Patent GB-1013781-A (GB)
Abstract: 1,013,781. Cold cathode tubes. HIVAC Ltd. Nov. 30, 1961 [Dec. 8, 1960], No. 42304/60. Heading H1D.  In a cold cathode gasdischarge tube, the cathode 10 is small relative to the anode 15 and is located within and substantially surrounded by the electrostatic field set up by it and the anode, and a trigger electrode 19 is arranged adjacent the cathode, between it and the anode. The anode may be an open cylinder, or one closed at one end by a metal cup 17 or by a mica disc extending to the tube walls and serving to support the anode, or may be semi-spherical with the cathode substantially at the centrepoint of the anode surface. The lower end of the anode may be closed by the flat portion 14 of the stem 13. The cylindrical trigger electrode 19 may have a wire 20 extending towards the pointed end 11 of the flat cathode 10. A keepalive electrode 22 may be postioned adjacent the anode, and the tube may be filled with a rare gas, a hydrogen, or a mixture of neon with about 1% of argon, krypton, or helium, at 30-50, or 200-300 mm./Hg.
Patent GB-1047351-A (GB)
IPC: B65D63/16
Abstract: 1,047,351. Strap fastenings. AEROQUIP A.G. Jan. 10, 1964 [Jan. 22, 1963], No. 1309/64. Heading E2A. A webbing assembly comprises a webbing strap 10 of woven construction having first and second spaced transverse slots 12<SP>1</SP>, 12<SP>11</SP> interwoven therein, the webbing being folded to form a loop wherein said slots are in juxtaposition, the slots being maintained in juxtaposed relationship by means of a webbing fitting comprising a member having a pair of spaced parallel fingers 24 interconnected at one end by a yoke portion 26, each one of said fingers being inserted into a different one of said spaced slots. As shown two identical said fittings are used, the fittings being inserted into the webbing from opposite sides so that each slot receives two fingers, one of each fitting. Each finger ends in a hook element 42 or 42<SP>1</SP> and each yoke portion has an upturned portion 34 or 34<SP>1</SP> which is bent substantially at right angles to the general plane of the member and which has a rectangular opening which receives the hook elements of the other U-shaped member, the hook elements engaging the outside surface of the portion 34 or 34<SP>1</SP> to retain the two members in fastened relationship.
Patent GB-1051735-A (GB)
IPC: A61K6/898
Abstract: 1,051,735. Artificial teeth. NATIONAL RESEARCH DEVELOPMENT CORPORATION. May 6, 1964 [May 8, 1963], No. 18192/63. Heading A5R. [Also in Division C1] Teeth or parts thereof are made from a composition containing at least 60% by weight of alumina, titania, ziresnia or their mixture the remainder being silica by firing at 1300‹- 1750‹C. to sinter acid precrystallize the side without fusion. A layer of porcelain can be fired on to a core of the composition with a veneer covering; or the composition can be shaped to fit a metal post fitted to the root canal of a living tooth. A reinforced porcelain jacket crown containing a preformed backing of the composition can be obtained by making a model stump and forming a platinum matrix from the model applying a thin coat of pigmented porcelain to the palatal face of the matrix acid vibrating the backing into position. The body colour is built up on to the remainder of the matrix with porcelain, and the whole fired to give the crown.
Patent GB-1052720-A (GB)
IPC: G06M1/276
Abstract: 1,052,720. Counters. LICENTIA PATENTVERWALTUNGS G.m.b.H. Sept. 10, 1965, No. 38764/65. Headings G4D and G4H. Counter read-out means comprises sensing levers movable in turn into contact with respective peripherally stepped discs of the counter and switch means arranged to pass electric pulses during said movement only. Referring to Fig. 1 (not shown), pulses to be counted are fed to an electromagnet 9 to permit a motor 1 to step the counter discs 20 to 23 which represent respective decimal orders. For read-out, a motor 12 rotates a magnet 17 to produce clock pulses from a read switch 18, and also rotates a cam shaft 59 which rocks four levers in turn causing each to rotate a corresponding sensing lever 30 to 33 via bushes with complementary notches and projections to engage a corresponding counter disc 20 to 23. On engagement, the projections slip from the notches causing a lateral displacement of the levers to open a reed switch 48 to terminate the passing of clock pulses to a central station. As a modification, the clock pulses may come originally from the central station and also drive motor 12 which could be a stepping motor.
Patent GB-1054193-A (GB)
IPC: G01N27/416
Abstract: 1,054,193. Determining relative quantities of fluid mixture constituents. LICENTIA PATENT-VERWALTUNGS-G. m. b. H. March 11, 1964 [March 29, 1963], No. 10247/64. Heading G1N. In a method of measuring very small quantities of metal ions in water, a known quantity of reagent at least sufficient to completely convert the metal ions of a group of chemically allied elements into chemical compounds is added to a quantity of the water and the quantity of reagent not used in the action is determined electro-chemically in an electrolyte which does not influence the equilibrium of the chemical reaction. Determination of the excess may be accomplished by the addition to the chemicals in the reaction vessel of a quantity of metal ions equivalent to the total amount of reagent initially added and measuring electro-chemically the quantity of metal ions not converted by the excess of reagent. Complex forming reagent such as ethylene diamine tetra-acetic acid is exemplified and a solution of 0À1 molar potassium nitrate, or a mixture of 0À1 molar potassium nitrate with 0À1 molar sodium acetate is suggested as electrolyte. An automatic process for repeated testing is described.
Patent GB-1054978-A (GB)
IPC: B62D53/08
Abstract: 1,054,978. Propelling vehicles. P. R. ANDERSON. Sept. 4, 1964 [Sept. 11, 1963], No. 36298/64. Heading B7H. [Also in Division B8] The tractor of a tractor and semi-trailer combination is provided with a device for loading and unloading the semi-trailer, when disconnected from the tractor, the device comprising a pair of interconnected telescopic jibs 22, 36 adapted to be luffed about an axis 26 behind the tractor cab by hydraulic rams 28 and pivotally supporting a fork with detachable tines 53. The fork is pivoted about the axis 44 by hydraulic rams 48 and the jib sections 36 are extended and retracted by rams mounted within the sections 22. The six rams are controlled by three levers of a valve 30 and the two levers controlling the rams 28, 48 may be interconnected by linkage to maintain the fork arms horizontal during luffing of the jibs. The jibs may be mounted so as to be rotatable about a vertical axis. The loading and unloading device may be used to assist in getting the tractor out of muddy areas by pivoting the fork down about the axis 44 and then retracting the rams 28 to raise the rear wheels from the ground. On extending the jibs, the tractor is rolled forward on its front wheels.
Patent GB-1225688-A (GB)
IPC: G01F23/24
Filed: 1968-09-24
Abstract: 1,225,688. Indicating liquid level. BLAW-KNOX CO. Sept. 24, 1968 [Oct. 19, 1967], No. 45299/68. Heading G1H. In a liquid level indicator device in which the level changes of an interface 4 between a liquid 2 and a vapour 3 in a vessel 1 are to be monitored, tubes 6, 7 connect the vapour and liquid portions 3, 2 of the vessel 1 to a column 8 in turn connected to a small diameter tube 11 the arrangement is such that temperature sensing means 13, 14, 15, or thermistors, are connected respectively to the tube 6 and above and below the interface 12 in tube 11 so that should the interface 12 rise the temperature at the sensor 14 will fall and as a result the algebraic signal imposed on the terminals of an amplifier will energize a relay coil 17 to actuate a signal such as a lamp or audible device and if the interface falls the temperature of the sensor 15 will rise to send a signal to a amplifier 18 to energize a signal relay coil 20. The amplified signals can be used to operate a solenoid or motor operated valve when the liquid level is too high or low, to shut off a valve in a burner fuel supply or open a valve in the liquid supply to the vessel 1.
Patent GB-1229706-A (GB)
IPC: F16L59/14
Filed: 1969-01-23
Abstract: 1,229,706. Lead-in insulators. COMPAGNIE GENERALE D'ELECTRICITE. 23 Jan., 1969 [26 Jan., 1968], No. 3985/69. Headings H2C and H2E. A fluid tight insulating bushing for passing a conductor 1 through a wall separating two spaces, one of which, 4, is cryogenic, comprises a ceramic sleeve 6 surrounding the conductor and two stainless steel rings 31, 35 sealed respectively to the conductor and to the wall 7 of the cryogenic chamber by metal bellows 33, 37. The ring 31 may be sealed to the conductor 1 through another stainless steel ring 9 and an aluminium ring 10. The rings 31, 35 may bear on the ends of the sleeve 6 through seatings 12, 36 of malleable metal such as indium. lead or tin, and the bellows 33, 37 may be welded respectively to the rings 31, 35 and to flanges 14b, 39 welded to the sleeve 6. The space 5, 40 surrounding the conductor and the wall 7 may be evacuated. Passages 16,27 communicate between the evacuated space and the bellows, the conductor may have a head 2 which bears on the ring 31 through resilient washers 17 and to which are attached conductors 3 which may be superconducting.
Patent GB-1231343-A (GB)
IPC: A01D34/66
Filed: 1969-05-19
Abstract: 1,231,343. Mowing machine. KUHN FRERES & CIE S.e.C.S. 19 May, 1969 [21 May, 1968], No. 25385/69. Heading A1F. A rotary scythe mower has separator elements 1 to orientate and re-erect any laid crop in a manner favourable to its cutting and is arranged so that no two adjacent cutting elements are driven with divergent rotational movement as seen on the side where uncut crop is presented for cutting, and no more than two immediately adjacent cutting elements are rotated in the same direction. The cutting elements may be such that their forward part, with respect to the direction of rotation, is inclined, domed or twisted downwards in order to create a vertically directed current of air.
Patent GB-1231904-A (GB)
IPC: G05F1/46
Filed: 1969-03-07
Abstract: 1,231,904. Automatic voltage control. ASSOCIATED ELECTRICAL INDUSTRIES Ltd. Jan.16, 1970 [March 7, 1969], No.12167/69. Heading G3R. A voltage stabilization arrangement for a high voltage D. C. source A supplying a load B such as an electron microscope or a testing arrangement, is made responsive to slow variations of the load voltage (Y) and to rapid variations of the source voltage (X) by shunting the resistance C, which limits the current in the event of a short circuit, by a series combination of capacitor F and resistance C1, the feedback voltage for the conventional control means E being taken from a voltage divider D connected between the point Z and the low voltage return path, e.g. earth. Resistors C, C1 may be similar or dissimilar in value and rated to withstand short circuit, whilst the capacitor may be protected by a surge diverter, spark gap, non- linear resistor or combination thereof. Members C, C1, F may be housed in a common tank.
Patent GB-1233159-A (GB)
IPC: B66B11/02
Filed: 1969-12-04
Abstract: 1,233,159. Lift cabins. INVENTIO A.G. 4 Dec., 1969 [6 Dec., 1968], No. 59173/69. Heading B8L. A lift cabin 1, comprises an outer frame 2 which supports a cabin floor 8, 11 and a cabin ceiling 9, which is resiliently urged towards the floor to retain side members 7 with their upper and lower ends in channels 8.1, 9.1, in the floor and ceiling. As shown, the ceiling is urged downwards by rubber buffers 16, 17 alternatively steel springs may be provided. Resilient moulded strips 20, 21 are provided in the channels 8.1, 9.1.
Patent GB-1239569-A (GB)
IPC: A61D3/00
Filed: 1969-05-31
Abstract: 1,239,569. Animal holding device. E. G. HOYME and C. L. HOYME. 31 May, 1969, No. 27688/69. Heading A5R. An animal holding device comprises a base 14, an elongated housing 12 extending upwardly from the base, an arcuate leg rest member 22 connected to the housing, leg clamps 18 slidable through the leg rest member and body restraining means 20 to engage the body of the animal, and actuating means connected to move the leg clamps and restraining means simultaneously. The housing comprises a curved and flat wall with interleaved corners held in position by a lock rod located in a tubular rim round the top of the housing. A platform 28 is supported in the housing by a chain 30 which engages with a tab 62 on the leg rest. The actuating means comprises a pull rod 64 connected at one end to a bracket secured to the leg clamps 18 and at the other end to a lever arm 72 which links with a one way locking member 74 through a tubular rod 86 containing a coil spring 88. The lever arm 72 includes a pedal portion 68 which, when depressed by the foot of the operator, moves the pull rod 64 to clamp the animal with the leg clamps 18 and moves the lever arm 72 to cause the tubular rod 86 to move into the housing and bring the restraining means 20 into engagement with the animal.
Patent GB-1251341-A (GB)
IPC: H02G15/24
Filed: 1968-02-02
Abstract: 1,251,341. Cable joints and terminations. ASSOCIATED ELECTRICAL INDUSTRIES Ltd. 3 Feb., 1969 [2 Feb., 1968], No. 5479/68. Heading H2E. A cable joint or termination comprises a preformed closed container filled with an insulating gas such as sulphur hexafluoride. As shown, applied to a stop-feed joint for an oil-filled cable, the annular closed container 28 is formed of a tubular shell 34<SP>1</SP>, of aluminium, copper or stainless steel, and an inner wall 32 of glass fibre filled epoxy resin. The container provides the main insulation for the joint. The inner surface of the shell 34<SP>1</SP> and the surface of a stress ring 48<SP>1</SP> connected to the conductor are coated with polyvinyl chloride, polyethylene or polymethylacrylate. Each cable carries a wrapping 54 of semi-conductive paper and a silica-filled epoxy resin stress cone 64, with a metallized surface 66 connected to the cable sheath 76 by a wrapping of wire 58. A casing 74<SP>1</SP> with an oil filling inlet 116 connects the container 28 to the cable sheath. Each stranded conductor 2 is crimped in a ferrule 10 formed integrally with a connector 8. The oil duct 4 in the cable connects with a transverse passage 20 initially closed by a valve member 92 held at the upper end of the passage by a magnet. After evacuation of the cable oil entering through the space 70 displaces the valve and flows into the cable.
Patent GB-1252207-A (GB)
IPC: A61K9/00
Filed: 1969-06-12
Abstract: 1,252,207. Gels containing silver salts. WYANDOTTE CHEMICALS CORP. 12 June, 1969 [19 June, 1968], No. 29963/69. Heading A5B. Compositions for the treatment of burns comprise a medicative amount of a water-soluble silver salt and, as a matrix therefor, an aqueous gel consisting essentially of, based on 100 parts by weight, (a) from 18 to 50 parts of a polyoxyethylene polyoxypropylene block copolymer of the formula:  wherein a is an integer such that the hydrophobe represented by (C 3 H 6 O) a  has a molecular weight of at least 2250, and b is an integer such that the hydrophile portion represented by (C 2 H 4 O) b  constitutes from 10 to 90 weight per cent of the polymer, and (b) from 50 to 82 parts of water. The compositions may be prepared by dissolving the copolymer in water at 35F to 50F, adding the silver salt and allowing the solution obtained to warm to room temperature, thereby forming a clear ringing gel. The silver salt may be silver nitrate, acetate, sulphate or lactate. The compositions may also contain antibiotics such as bacitracin and neomycin sulphate; hormones such as cortisone and hydrocortisone, vitamins such as vitamin A; lanolin, glycerine, and other oils.
Patent GB-1257144-A (GB)
IPC: H04N5/073
Filed: 1970-07-08
Abstract: 1,257,144. Transistor phase shifting circuits; colour television. FERNSEH G.m.b.H. 8 July, 1970 [12 July, 1969], No. 33113/70. Headings H3T and H4F. [Also in Division H2] A phase shifter, for example for coarse correction in the colour sub-carrier distribution network in a television studio, comprises means 2 to produce from the input wave two signals mutually 60 or 120 degrees out of phase, a pair of switches 7, 8 and 9, 10 connected to each, one of each pair of connections including a phase inverter 5, 6, and means 11 for combining the outputs of the switches. It is explained that adjustment in 60 degree steps may be obtained without altering the output amplitude. In Fig. 2, the colour sub-carrier input at 1 is fed to two phase shifters 31, 32; 33, 34. The output at 3 is fed to gates 51, 52 via erect and inverting halves of the secondary winding of transformer 39 and the output at 4 feeds gates 64 and 65. The outputs of the gates are added via transistors 57, 70, according to whether positive, negative or zero voltages are applied at 60 and 73 to render the corresponding Zener diodes conductive, or not, so one or other or neither of the gates of the pairs conduct.
Patent GB-1258095-A (GB)
IPC: C08B11/08
Filed: 1969-03-18
Abstract: 1,258,095. Insolubilized enzymes; cellulose ethers. RANKS HOVIS McDOUGALL Ltd. 3 March, 1970 [18 March, 1969; 11 Dec., 1969], Nos. 14074/69 and 60474/69. Headings C3A and C3H. Pullulanase, carboxypeptidase, dextranase or papain is rendered insoluble by reacting it, dissolved in a buffer at pH 6À5 to 8À6 with the pdiazophenoxy-hydroxypropyl ether of cellulose. The p-diazophenoxy-hydroxypropyl ether of cellulose is prepared by the reaction of cellulose with p-nitrophenyl glycidyl ether and sodium hydroxide in a nitrogen atmosphere, followed by reduction by TiCl 2  and diazotization.