baber/WOPTO huggingface dataset:
Patent CA-2990177-A1 (CA)
Inventor: MA YUPO
IPC: C12N5/0783
Filed: 2016-06-24
Abstract: The present invention relates to compositions and methods relating to chimeric antigen receptor (CAR) polypeptides and methods relating thereto. In one embodiment, the present invention relates to engineered cells having chimeric antigen receptor polypeptides directed to at least two targets. In another embodiment, the present invention relates to engineered cells having chimeric antigen receptor polypeptides and an enhancer moiety.
Patent CA-2991903-A1 (CA)
Inventor: NASSIF RABIH
IPC: A61N1/04
Filed: 2016-07-08
Abstract: An implantable pulse generator that includes a current source/sink generator is disclosed herein. The current source/sink generator includes a current drive differential amplifier. The current driver differential amplifier is configured to selectively source current to, or sink current from a target tissue. The current drive differential amplifier includes an inverting input and a non-inverting input. One of the inputs of the current drive differential amplifier is connected to a virtual ground, and the other is connected to a current command. A stimulation controller can supply a voltage to the other of the inputs of the current drive differential amplifier to select either current sourcing or current sinking.
Patent CA-2994465-A1 (CA)
Inventor: TANG RAYMOND YUE-SING
IPC: A61M25/095
Filed: 2018-02-08
Abstract: An electrophysiologic device may be constructed with an elongated body having proximal and distal ends a lumen. At least one coil may be formed around a distal portion of the elongated body from a plurality of helical wraps of a continuous wire that extends to the proximal end of the elongated body through the lumen. One or more coils may be provided and each may be configured to function as either a ring electrode or a location sensor.
Patent CA-2996254-A1 (CA)
Inventor: NIKLEWSKI ANDRZEJ
IPC: B02C2/04
Filed: 2016-08-19
Abstract: L'invention concerne un dispositif de broyeur tel qu'un broyeur à cône ou giratoire, lequel dispositif de broyeur comprend : un arbre (2) définissant une première direction parallèle à sa longueur, l'arbre comprenant une extrémité d'arbre supérieur (2a) ; une tête de broyeur (12) ; et un dispositif de sécurité contre les surcharges (30) accouplant la tête de broyeur à l'extrémité d'arbre supérieure, le dispositif de sécurité contre les surcharges comprenant un dispositif de sollicitation conçu pour solliciter la tête de broyeur de façon à l'éloigner de l'extrémité d'arbre supérieure dans la première direction, et dans lequel : le dispositif de sécurité contre les surcharges (30) est conçu pour permettre le déplacement de la tête de broyeur le long de la première direction par rapport à l'arbre en réponse à une force agissant sur la tête de broyeur dans la première direction.
Patent CA-2996893-A1 (CA)
Inventor: MORGAN RICHARD
IPC: A61K39/395
Filed: 2016-08-30
Abstract: L'invention concerne des compositions améliorées pour des thérapies cellulaires adoptives pour les cancers qui expriment le glycoépitope sur TAG-72.
Patent CA-2997078-A1 (CA)
Inventor: PUGH RANDALL B
IPC: G02C7/16
Filed: 2018-03-01
Abstract: This invention discloses methods and apparatus for providing a variable aperture insert into a lens. A liquid crystal layer may be used to provide a variable aperture function and in some examples. In other examples, electrochromic, photochromic, liquid meniscus or electroactive elastomeric devices may form a light blocking element of a variable aperture insert. In some examples, an ophthalmic lens is cast-molded from a silicone hydrogel including a variable aperture insert.
Patent CA-2998447-A1 (CA)
Title: Outil pour rugosifier la surface d'un trou de forage
Inventor: LEDERLE HANS-PETER
IPC: B23B27/00
Filed: 2016-09-19
Abstract: L'invention concerne un outil pour rugosifier la surface d'un trou de forage, comprenant une partie d'accouplement (12) pour la fixation de l'outil (10) dans un dispositif de forage, et une tête d'outil (14) pour modifier la surface du trou de forage, la tête d'outil (14) étant pourvue de moyens de coupe (18) sur sa périphérie. Afin de permettre une rugosification simple de la surface d'un trou de forage, la tête d'outil (14) comporte au moins une fente latéralement traversante (20) partant d'un bout (22) de la tête d'outil (14) et s'étendant le long de l'axe longitudinal (A) de l'outil, ce qui permet de réduire au minimum l'influence de l'utilisateur tout en augmentant le confort d'utilisation.
Patent CA-3000449-A1 (CA)
Title: Hockey goalkeeper leg pad
Inventor: FILIATRAULT-GIROUX MATHIEU
IPC: A63B71/12
Filed: 2018-04-05
Abstract: A hockey goalkeeper leg pad includes a pad body and flaps extending from the pad body. The flaps including lateral and medial flaps spaced-part to define a leg channel. An inner strap is extendable across the leg channel to releasably attach one of the medial flaps to one of the lateral flaps. The inner strap is resilient along at least a longitudinal segment. The longitudinal segment is stretchable along a longitudinal axis of the inner strap to increase in length. An outer strap is extendable across the leg channel to releasably attach an outermost one of the medial flaps to an outermost one of the lateral flaps. The outer strap is less resilient than the longitudinal segment of the inner strap.
Patent CA-3001267-A1 (CA)
Inventor: HEUFT BERNHARD
IPC: B65G21/20
Filed: 2016-11-07
Abstract: The invention relates to a device and a corresponding discharge method for discharging objects (16) with a respective axially symmetrical standing surface (18). The axially symmetrical standing surface has the shape of a regular polygon with a five-fold axial symmetry. The device comprises an aligning device (12), a discharge device (14), and a transport device (10), on which the objects are conveyed in a single row and in a mutually spaced manner from the aligning device to the discharge device. At least one railing (22) is provided on one side of the transport device at least in the region of the aligning device. The aligning device is designed such that the objects are pressed against the railing and are aligned in the process such that an axis of symmetry of the axially symmetrical standing surface extends on the transport plane perpendicularly to the railing, and the objects are then supplied to the discharge device in this alignment. The discharge device is oriented such that one of the corners of the standing surface of the objects points in the direction in which the objects are discharged.
Patent CA-3008130-A1 (CA)
Inventor: MADDOCKS IAN
IPC: H04W12/06
Filed: 2016-12-08
Abstract: A method of authentication of a user at a computing device (1) is provided suitable for a transaction or for use of a remote service. A plurality of authentication options is provided to the user at the computing device (1). On selection of an authentication option by the user, an authentication protocol is performed for the selected authentication option. On successful performance of the authentication protocol, the computing device communicates with the remote service to provide a confirmation of successful authentication for the remote service with an identification of which of the plurality of authentication options was selected by the user. This approach can be used to enable transactions by a delegated user, and in fraud detection and prevention. Suitable computing devices and service offerings are also described.
Patent CA-3008607-A1 (CA)
Inventor: SHISHIDO TAKAO
IPC: A61K31/53
Filed: 2016-12-14
Abstract: A) Formula (I) A medicine that is useful for treating or preventing influenza, etc., said medicine being characterized by comprising a combination of: (A) a compound represented by formula (I), a pharmaceutically acceptable salt thereof, or a solvate of the same [in formula (I): P represents a hydrogen atom or a prodrug-forming group; A1 represents CR1AR1B, S or O; A2 represents CR2AR2B, S or O; A3 represents CR3AR3B, S or O; A4's independently represent CR4AR4B, S or O; (wherein: the ring-constituting atoms of the ring formed by A1, A2, A3, A4's, the nitrogen atom adjacent to A1 and the carbon atom adjacent to A4's include 1 or 2 hetero atoms; R1A and R1B independently represent a hydrogen atom, halogen, alky, etc.; R2A and R2B independently represent a hydrogen atom, halogen, alky, etc.; R3A and R3B independently represent a hydrogen atom, halogen, alky, etc.; R4A's independently represent a hydrogen atom, halogen, alky, etc.; R4B's independently represent a hydrogen atom, halogen, alky, etc.; and R3A and R3B may form, together with the carbon atom adjacent thereto, a non-aromatic carbon ring or a non-aromatic heterocyclic ring); n is an integer of 1-2; and R1 is a group represented by formula (2), etc.]; with (B) a compound having an anti-influenza effect, a pharmaceutically acceptable salt thereof, or a solvate of the same, and/or an antibody having an anti-influenza effect.
Patent CA-3009182-A1 (CA)
Inventor: DHIMAN RAJEEV
IPC: A61L2/10
Filed: 2016-12-19
Abstract: A system includes multiple devices configured to emit and detect germicidal radiation. Each of the multiple devices operates in emitting mode when connected to a drive source in a forward bias configuration and operates in detecting mode when disconnected from the drive source or when connected to the drive source in a reverse bias configuration. Cycling circuitry generates a sequence of control signals that control switching circuitry to change the connections of the devices to the drive source in a cycle in which one or more of the multiple devices are switched to detecting mode and senses radiation emitted by one or more of the multiple devices simultaneously operating in emitting mode. Each device operating in detecting mode generates a signal in response to the sensed radiation. Detection circuitry detects signals of the devices operating in detecting mode and generates a detection output in response to the detected signals.
Patent CA-3012414-A1 (CA)
Title: Airflow cooking device
Inventor: DELRUE OLIVIER
IPC: A47J37/06
Filed: 2017-02-10
Abstract: A cooking appliance comprising: ventilation means arranged to create an airflow in a cooking space of the appliance, a cooking basket (20), for receiving food products to be cooked in the cooking space and allowing the airflow to pass through a bed of food products to be cooked, and heating means (30) for heating the airflow, wherein the ventilation means comprise a cross-flow fan (10), the heating means are arranged downstream of the ventilation means, in the airflow, and the cooking basket is arranged downstream of the heating means.
Patent CA-3013249-A1 (CA)
Title: Dispositif mobile de projection pour scenographie lumineuse
Inventor: LIGOT PHILIPPE ANDRE CONSTANT
IPC: G03B21/16
Filed: 2018-08-02
Abstract: Dispositif mobile de projection (10, 210) pour scénographie lumineuse, comprenant un engin routier (12) muni d'une structure (14, 214) montée sur roues (16), et au moins une unité de projection lumineuse (50, 250) montée sur la structure (14, 214) et configurée pour être commandée de façon à réaliser une scénographie lumineuse dans l'environnement extérieur du dispositif mobile de projection (10, 210).
Patent CA-3013530-A1 (CA)
Inventor: BELLORINI LORENZO
IPC: A61K47/69
Filed: 2017-02-24
Abstract: La présente invention concerne un nouveau composite à base d'hydroxypropyl-ß-cyclodextrine, de sucralose, d'un composant pharmaceutiquement actif (API) complexé dans ladite hydroxypropyl-ß-cyclodextrine, et facultativement un véhicule aqueux. Le composite peut être obtenu par un processus de complexation de l'API dans l'hydroxypropyl-ß-cyclodextrine, en présence de sucralose. Le composite assure une biodisponibilité d'API étonnamment élevée par voie d'absorption buccale, grâce à un taux d'absorption élevé à travers la membrane buccale. Par conséquent, le composite est adapté pour la préparation de compositions pharmaceutiques oromuqueuses, par exemple des comprimés buccaux ou sublinguaux, un film orodispersible, etc., ayant une biodisponibilité élevée.
Patent CA-3013881-A1 (CA)
Inventor: MARTNER ANNA
IPC: C07K16/30
Filed: 2017-02-08
Abstract: The present invention provides methods of treating cancer in a subject, preventing or delaying relapse to a cancer in a subject in remission, prolonging remission from cancer, increasing survival, and decreasing or alleviating cancer symptoms comprising a) administering histamine dihydrochloride and an inhibitor of the Programmed cell Death protein 1 (PD-1)/Programmed Death Ligand 1 (PD-L1) or b) administering an agent that decreases reactive oxygen species (ROS) optionally, together with a histamine receptor agonist. The present invention also provides methods of predicting the efficacy of a cancer treatment based on a re-distribution of cytotoxic T cells, frequency of NK cells, or other biochemical changes, and related methods of preventing relapse to cancer and for prolonging remission from a cancer. Related kits and compositions are also provided.
Patent CA-3015652-A1 (CA)
Inventor: ABULA MAHEMUTI
IPC: D06M15/00
Filed: 2017-02-28
Abstract: L'invention concerne des fibres, des tissus et d'autres substrats de soies électroconducteurs. L'invention concerne également des tissus de fibres et d'autres articles de fabrication produits à l'aide dudit procédé. Le procédé et les articles de fabrication sont particulièrement utiles dans des vêtements fonctionnels, par exemple des vêtements d'extérieur, des gants, et dans des dispositifs dans lesquels une conductivité électrique est souhaitable. Des dispositifs représentatifs comprennent un substrat ou un composant en fibre, en tissu ou en cuir.
Patent CA-3020389-A1 (CA)
Inventor: STENMAN LOTTA
IPC: A61K35/745
Filed: 2017-04-06
Abstract: This invention relates to the use of a composition comprising a bacterium of the genus Bifidobacterium, particularly, but not exclusively, a bacterium of the Bifidobacterium animalis ssp. lactis (strain) 420 (B420), and one or more prebiotics and/or fibres, for use in increasing lean body mass in a mammal.
Patent CA-3020677-A1 (CA)
Inventor: FREER BENJAMIN AVERY
IPC: G01R31/02
Filed: 2017-04-10
Abstract: A system to determine the ground impedance of a conduit system includes a conductive sheath and a resistor of known value. The conductive sheath is configured to surround a portion of a conductor housed within a conduit system. Capacitive coupling occurs between the sheath and the conductor to establish a voltage source. The resistor is electrically coupled between the voltage source and a metal component of the conduit system, and a voltage drop is read across the resistor to determine the health of the ground impedance of the conduit system.
Patent CA-3022765-A1 (CA)
Inventor: BARBOUR ROBIN
IPC: C07K16/18
Filed: 2017-05-02
Abstract: L'invention concerne des anticorps qui se lient spécifiquement à la protéine tau. Les anticorps inhibent ou retardent des pathologies associées à la protéine tau et la détérioration symptomatique associée.
Patent CA-3026372-A1 (CA)
Inventor: DELLINGER DOUGLAS J
IPC: C12N15/10
Filed: 2017-06-08
Abstract: The present invention relates to guide RNAs having chemical modifications and their use in CRISPR-Cas systems. The chemically modified guide RNAs have enhanced specificity for target polynucleotide sequences. The present invention also relates to methods of using chemically modified guide RNAs for cleaving or nicking polynucleotides, and for high specificity genome editing.
Patent CA-3026432-A1 (CA)
Inventor: CLAUS MICHAEL J
IPC: A61F9/007
Filed: 2009-11-06
Abstract: A phacoemulsification system includes a handpiece that includes a needle having at least one port, a first pump and a second pump. The needle has at least one port and is configured to move in a substantially longitudinal and a non-longitudinal direction. The first pump is configured to operate when a longitudinal cutting mode is selected. The second pump is configured to operate when a non-longitudinal cutting mode is selected.
Patent CA-3027640-A1 (CA)
Inventor: SKIFFINGTON RODNEY
IPC: D06F59/00
Filed: 2018-12-14
Abstract: A forced air apparatus has an air blower, an air conduit and a diffusion body. The air blower has an air intake, an air outlet and a blower motor. The air conduit has a first end and a second end. The first end is connectable to the air outlet of the air blower. The diffusion body has an air conduit connection and at least one air outlet. The air conduit connection allows for removable connection of the second end of the air conduit to the diffusion body such that air flows from the air blower to the diffusion body. The at least one air outlet allows air to flow out of the diffusion body
Patent CA-3028502-A1 (CA)
Title: Use of augmented reality to assist navigation during medical procedures
Inventor: ALTMANN ANDRES CLAUDIO
IPC: A61B34/20
Filed: 2018-12-24
Abstract: Physicians performing invasive procedures require accuracy and precision when working with surgical tools. Surgical procedures are increasingly becoming minimally invasive, with physicians operating using cameras to view the surgery site and directing their tools through oculars or video displays. Ideally, the physician should be able to perform the invasive procedure while simultaneously observing both the real-time image of the patient and additional data critical for his medical decisions about the manipulation of the surgical tool and the next surgical step. The augmented reality navigation system of the present disclosure provides tool location visibility for invasive procedures through the use of location sensors included on a camera and/or on the tools used during a procedure. A location tracking system determines and monitors the locations of the tools and camera based on the characteristics of signals detected by the sensors and displays informational overlays on images obtained with a camera.
Patent CA-3028533-A1 (CA)
Inventor: CROZIER ETIENNE
IPC: A47J31/46
Filed: 2017-06-16
Abstract: A beverage preparation machine comprising a source of liquid and a dispensing outlet connected via a pump that includes a chamber and a displaceable wall delimiting the chamber. The pump may further comprise an electric actuator driving the displaceable wall for causing an inflow of liquid from the source into the chamber and for causing an outflow of liquid from the chamber to the dispensing outlet. The machine may comprise a powering unit with a sensor for measuring an electrical parameter representative of a consumption of power by the actuator and a control unit that is connected to the sensor configured to control the power supplied to the actuator by the electric power source as a function of the measured parameter and a desired liquid input into the chamber and/or liquid output from the chamber.
Patent CA-3029100-A1 (CA)
Inventor: DAIGLE JEAN-CHRISTOPHE
IPC: H01M4/62
Filed: 2017-06-30
Abstract: This application describes a process for the preparation of carbon-coated particles, where the particles comprise an electrochemically active material. The process comprises the steps of emulsion polymerization, drying and thermally treating the polymer to obtain a nano-layer of carbon on the particles, where the carbon layer comprises fibers and nitrogen-containing polyaromatics have a graphene-like structure. The application also further relates to the particles produced by the method as well as to electrode materials, electrodes and electrochemical cells comprising the particles.
Patent CA-3030049-A1 (CA)
Inventor: JAKOBSSON NIKLAS BENGT
IPC: B01D53/86
Filed: 2017-06-13
Abstract: A process for combined removal of siloxanes and sulfur-containing compounds from biogas streams, such as streams from landfills or anaerobic digesters, comprises heating the biogas stream and optionally mixing it with air, feeding the gas to a first filter unit with high temperature resistance, injecting a dry sorbent into the first filter unit to capture siloxanes present in the gas, recycling part of the exit gas from the first filter unit to the inlet thereof for the sulfur-containing compounds to be captured by the dry sorbent or optionally to a second filter unit inlet for the sulfur-containing compounds to be captured by a sulfur-specific sorbent and recovering clean gas from the first or optionally from the second filter unit.
Patent CA-3031624-A1 (CA)
Inventor: JOHANSSON PATRIK
IPC: A61Q11/00
Filed: 2016-09-07
Abstract: L'invention concerne un récipient de produit. Le récipient selon l'invention comprend un premier produit et un dispositif d'électrochimie configuré pour convertir une partie du premier produit en un deuxième produit qui est une préparation instable.
Patent CA-3031685-A1 (CA)
Title: Oral care implement and filament for the same
Inventor: NELSON STEPHEN
IPC: A46D1/00
Filed: 2017-08-28
Abstract: A mechanically tapered bristle filament for an oral care implement. The filament is characterized by a long thin tapered end portion. The tapered end portion has a taper length and tip diameter comparable to chemically tapered filaments. The areal surface roughness of the tapered end portion however is greater than chemically tapered filaments thereby producing increased scrubbing action against the surfaces of the teeth. The foregoing taper and roughness characteristics of the present filament enhance inter-dental cleaning effectiveness.
Patent CA-3032863-A1 (CA)
Inventor: MAHMUD ALMOSTASIM
IPC: G01N33/00
Filed: 2017-08-18
Abstract: L'invention concerne un procédé et un système de formation de motifs soustractive d'un substrat, qui sont utilisés dans la fabrication de dispositifs analytiques microfluidiques à base de papier (pPADs). En faisant adhérer le substrat sur un matériau de support imperméable, le substrat est gravé pour produire des caractéristiques de haute résolution, qui peuvent être utilisées pour construire des MPADS capables de faire circuler et de tester des volumes d'échantillon extrêmement petits. Ce système et ce procédé peuvent être modifiés pour divers substrats pour construire des caractéristiques pour des systèmes d'écoulement bidimensionnels et tridimensionnels. Un ensemble substrat est formé en fixant une couche de substrat (par exemple du papier) à une couche imperméable (par exemple une feuille). Des parties de la couche de substrat sont coupées à l'aide d'un dispositif de gravure pour former un ou plusieurs motifs soustractifs sur l'ensemble substrat en vue de définir des régions d'écoulement de fluide.
Patent CA-3035103-A1 (CA)
Title: Infill panel and operable fenestration frame adjustment system
Inventor: GREGORY HEADER A
IPC: E06B3/26
Filed: 2019-02-28
Abstract: A system for adjusting infill panel or operable fenestration frame in an operable fenestration. The system can include a setting block adjustment device and an operable fenestration frame such as a door rail or window sash with glass, acrylic, polycarbonate or other infill material. The setting block adjustment device can include a lug, a threaded fastener, a setting block support plate, and a setting block. The lug is slidably captive within a groove in an outer face of the operable fenestration. The threaded fastener engages a threaded aperture within a blind hole in the lug. The fastener end engages the setting block support plate and setting block to adjust the infill panel.
Patent CA-3035228-A1 (CA)
Title: Systemes et procedes de surveillance de vibrations pendant le transport de marchandises
Inventor: NYGREN BLAIR
IPC: G08B25/10
Filed: 2017-08-17
Abstract: Procédé d'estimation d'un niveau de dommage causé à une cargaison périssable pendant le transport de la cargaison à l'aide de données collectées par un dispositif de surveillance portatif. Le procédé consiste à mesurer des données de vibration associées à la cargaison. Les données de vibration sont surveillées par un capteur de vibration du dispositif de surveillance portatif. Le procédé consiste en outre à incrémenter un compteur dans le dispositif de surveillance portatif en réponse à une amplitude des données de vibration mesurées dépassant un seuil prédéterminé. Le procédé consiste également à déterminer si la valeur de compteur dépasse une valeur prédéterminée, et à générer une alerte indiquant un dommage causé à la cargaison dès qu'il est déterminé que la valeur de compteur a dépassé la valeur prédéterminée.