baber/WOPTO huggingface dataset:
Patent CO-6140072-A2 (CO)
Title: Metodo para la deteccion de diagnostico de cancer que implica cebadores y sondas para la deteccion especifica del marcador mage-3
Inventor: BEER GABRIELE ANNE-MARIE
IPC: C12Q1/68
Filed: 2008-12-24
Abstract: 1.- Un cebador que comprende la secuencia de nucleótidos de cualquiera de SEQ ID NO. 3-12.2.- Un conjunto de cebadores que comprenden uno o más de los siguientes pares de cebadores:a) SEQ ID NO: 3 y 4;b) SEQ ID NO: 5 y 6;c) SEQ ID NO: 7 y 8;d) SEQ ID NO: 9 y 10; ye) SEQ ID NO: 11 y 12.3.- Un conjunto de cebadores que comprenden uno o más de los siguientes pares de cebadores:a) SEQ ID NO: 3 y 4; yb) SEQ ID NO: 5 y 64.- Un conjunto de cebadores que comprenden uno o más de los siguientes pares de cebadores:a) SEQ ID NO: 7 y 8;b) SEQ ID NO: 9 y 10; yc) SEQ ID NO: 11 y 12.5.- Una sonda que comprende la secuencia de nucleótidos de cualquiera de SEQ ID NO: 13 a 17, 53 ó 54.6.- Un kit que comprende:(i) un cebador de avance;(ii) un cebador de retroceso; y(iii) una sonda, en donde los componentes (i), (ii) y (iii) tienen la capacidad de hibridar a una secuencia objetivo de MAGE-A3 bajo condiciones estrictas, y en donde al menos una de las secuencias objetivo de (i), (ii) o (iii) difiere en al menos un nucleótido en comparación con la región equivalente de las otras secuencias de nucleótidos MAGE-A y en donde el conjunto tiene la capacidad de utilizarse para discriminar entre MAGE-A3 y MAGE-A6.
Patent CO-6491060-A2 (CO)
Title: Compuestos y composiciones para el tratamiento de enfermedades parasitarias
Inventor: CHATTERJEE ARNAB K
IPC: A61K31/4985
Filed: 2012-01-19
Abstract: Compuestos de Fórmula la, Ib y Ic:sales farmacéuticamente aceptables de los mismos, activos en el tratamiento del paludismo y composiciones farmacéuticas que los comprenden.
Patent CO-6592097-A2 (CO)
Title: Composiciones endoparasiticidas
Inventor: ROLFE PETER
IPC: A01N37/34
Filed: 2012-09-06
Abstract: La presente invención se relaciona con nuevas composiciones endoparasiticidas y su uso en el control de endoparásitos, en particular en helmintos.Las composiciones de la presente invención pueden comprender el componente (A) y el componente (B)y cualquier relación de peso apropiada, por ejemplo en una relación entre 1:100 y 100:1 peso por peso, preferiblemente en una relación entre 1:1 y 50:1 peso por peso, más preferiblemente en una relación entre 1:1 y 25:1 peso por peso y más preferiblemente de 5:1 a 15:lpeso por peso.De acuerdo con la presente invención, en un aspecto se relaciona con una composición para el control de los endoparásitos en y sobre animales, el cual comprende una combinación, en proporciones variables, de (A) un compuesto de fórmula (I)isómeros ópticos, enantiómeros individuales del compuesto de la fórmula 1 y mezclas de los mismo, incluyendo racematos. El compuesto de la fórmula 1 puede existir en más de una forma tautomérica. La presente invención abarca todos los tautómeros, así como mezclas de los mismos. El compuesto de la fórmula 1 puede ser capaz de formar sales con ácidos o bases. La presente invención incluye dicho compuesto de la fórmula l en forma de una sal hasta un grado que es farmacéuticamente y desde el punto de vista veterinario aceptable. El compuesto de la fórmula 1 y sus sales puede existir en una forma no solvatada o solvatada.El componente (B) de las composiciones de la presente invención es abamectina, también llamada avermectina B1, CAS Registry Numero 71 751-41-2.La abamectina es una mezcla de dos compuestos de la fórmulaLa avermectina B1a, del compuesto de la fórmula (II), en donde R es etilo, el cual es el principal componente; yLa avermectina B1b, del compuesto de la fórmula (II), en donde R es metilo, el cual es el compuesto menor.
Patent CO-6680619-A2 (CO)
Title: Formulaciones
Inventor: BELL GORDON ALASTAIR
IPC: C07C69/00
Filed: 2013-01-23
Abstract: Esta invención se refiere a una formulación que comprende un compuesto de fórmula (I)en donde Ry Rson cada uno independientemente hidrógeno, alquilo Copcionalmente sustituido, alquenilo Copcionalmente sustituido, cicloalquilo Copcionalmente sustituido, cicloalquenilo Copcionalmente sustituido o arilo opcionalmente sustituido; siempre que el número total de átomos de carbono en Ry Rsea un número entero de 5 a 40 inclusive; el uso de un compuesto de fórmula (I) (i) como un adyuvante siempre que el número total de átomos de carbono en Ry Rsea un número entero de 5 a 40 inclusive; y (ii) como un disolvente siempre que el número total de átomos de carbono en Ry Rsea un número entero de 5 a 20 inclusive; a ciertos compuestos novedosos de fórmula (I) y a un proceso para preparar dichos compuestos novedosos.
Patent CO-6751283-A2 (CO)
Title: Derivados de 3,4-dihidropirrolo[1,2-a]pirazin-1-ilamina útiles cini inhibidores de beta-secretasa (bace)
Inventor: TRABANCO-SUAREZ ANDRES AVELINO
IPC: C07D487/04
Filed: 2013-08-29
Abstract: La presente invención se refiere a derivados de 3,4-dihidropirrolo[1,2-a]pirazin-1-ilamina como inhibidores de beta-secretasa, conocida también como la enzima que escinde la proteína precursora de amiloide por el sitio beta, BACE, BACE1, Asp2 o memapsina 2. La invención también se refiere a composiciones farmacéuticas que comprenden tales compuestos, a procesos para preparar tales compuestos y composiciones, y al uso de tales compuestos y composiciones para prevenir y tratar trastornos en los que participa la beta-secreta, tales como la enfermedad de Alzheimer (EA), el deterioro cognitivo leve, senilidad, demencia, demencia con cuerpos de Lewy, síndrome de Down, demencia asociada con el accidente cerebrovascular, demencia asociada con la enfermedad de Parkinson o demencia asociada con beta-amiloides.
Patent CO-6990738-A2 (CO)
Title: Agentes de reversion anticoagulante
Inventor: STEINER SOLOMON S
IPC: C07D241/04
Filed: 2014-06-26
Abstract: Se describen compuestos de reversión de anticoagulantes novedosos, así como también métodos para fabricar los compuestos, composiciones farmacéuticas que incluyen los compuestos, métodos para utilizar los compuestos para revertir los efectos anticoagulantes de los inhibidores de la coagulación y ensayos de diagnóstico que comprende los compuestos.
Patent CO-7200275-A2 (CO)
Title: Elastómero de poliurea con incrementada resistencia a productos químicos
Inventor: OTERO MARTINEZ IRAN
IPC: C09D175/02
Filed: 2015-02-13
Abstract: La presente invención se refiere a un procedimiento para preparar elastómeros de poliurea, en el cual (a) se mezclan poliisocianatos con (b) poliaminas, (c) opcionalmente prolongadores de cadenas de amina que contienen grupos amina primarios o secundarios, (d) opcionalmente polioles y (e) opcionalmente auxiliares y aditivos, para formar una mezcla de reacción y se los endurece, y en el que por lo menos uno de los componentes (a) a (d) contiene partículas de relleno dispersas.
Patent EP-1026300-A2 (EP)
Inventor: HUSS ROLF
IPC: D04B35/28
Filed: 2000-01-04
Abstract: The lubrication system (1), for a number of lubricating points and especially at a knitter, has a distribution unit (7b) which is part of the pump unit (7a).  The cylinder (8) has a number of outlet channels, controlled by the piston (21). The cylinder (8) has a cylindrical wall, with the outlet channels passing through the wall. The piston (21) has at least one control channel at its mantle surface, which forms the distribution section (7b) by rotation of the piston (21) in alignment with at least one outlet channel, with the piston (21) rotating within the cylinder (8). The pump unit (7a) and the distribution unit (7b) are linked to a drive (33), which includes a rotating (55) and a sliding section both connected to the piston (21). The rotating section (55) has a setting motor, preferably as a step motor, to give the required rotary setting. The step motor is keyed to the piston (21) by a coupling with a fixed rotary play. The piston (21) has a locking unit (48) to give a keyed lock to the piston (21) to allow an axial movement in selected rotary positions, by acting on a locking wheel keyed to the piston. The lock (48) is moved in and out of contact with the piston locking wheel by a setting drive (51). The locking wheel is a ratchet wheel, and the lock (48) is a ratchet pawl. The sliding section is operated by the rotary drive (55), through a gearing which converts the relative rotary movement between the piston (21) and the rotary drive (55) into a piston (21) linear movement. The gearing has two threaded components where one is keyed to the piston (21) and the other is keyed to the rotary drive (55). At least one threaded component is connected to a magnet (62) to tense them against each other. A control sets the stroke movements of the piston (21). A sensor (66) monitors the piston (21) movements. An entry channel (12) leads into the cylinder (8), with the channels (5) linked to the outlet channels each with a non-return valve. An Independent claim is included for a lubricating action, to a number of lubrication points, with at least one pump. The lubricant is passed intermittently from the pump through the lubricating lines to the lubrication points, and the lines from the pump are subjected to variable pressures on a timed program. Preferred Features: The assembly gives a pressure modulated lubricating action. The lubricating operation contains a pressure pulse, which is a series of separate pulses with a pressure drop between them, which does not fall below the min. pressure level.
Patent EP-1020392-A2 (EP)
Inventor: SCHUMANN RAINER
IPC: B65H29/12
Filed: 2000-01-14
Abstract: The oppositely disposed runs of the conveyor belts(9,17) include an acute angle when viewed at right angles to the direction of transportation. At least one device for guiding and spacing change of the run of one conveyor belt relative to the other conveyor belt is provided at least in the working area of the ejector. At least one swinging arm pivots around an axis extending parallel to the running direction of the conveyor belts and on its free end has a guiding means for the run of the conveyor belt.
Patent EP-1033146-A2 (EP)
Inventor: GOEBEL UDO
IPC: A61M39/12
Filed: 2000-01-21
Abstract: Catheter coupling has two jaws (10, 11) and a channel with a hose section (35) for accommodation of an end section of a catheter (30). The jaws at one end are joined to one another by a hinge (12) and at the opposite ends are locked to one another by locking elements (17, 18).
Patent EP-1033464-A2 (EP)
IPC: B60J1/17
Filed: 2000-02-29
Abstract: A power window apparatus capable of opening a window or
windows of a submerged automobile by manually operating a
driver seat window open switch or a passenger seat window
open switch both located on a driver seat window operation
unit. The driver seat window operation unit and passenger
seat window operation units have each a window close switch,
a window open switch, a window open/close motor, and a motor
drive controller. The driver seat window operation unit has
a submersion detector for generating a submersion detection
signal, a motor drive controller incorporating a control
driver for opening windows when the driver manually operates
corresponding window open switches, and connection lines for
connecting normally close contacts of passenger seat window
open switches located on the driver seat window operation
unit with the normally close contacts of the window open
switches located on the passenger seat window operation
units.
Patent EP-1020779-A2 (EP)
Inventor: WALTON HERBERT H
IPC: G05D16/06
Filed: 1997-08-19
Abstract: A fluid control valve having a valve body, a cage, and a
flexible elastomeric diaphragm with a formed convolution to
fully open the cage opening. An elastomeric diaphragm
regulator with a flow diverter in the fluid flow path to
reduce fluid flow separation and thereby reduce the required
flow recovery area before pressure throttling. A raised
knife edge seat located on the cage top in a position of
stagnant fluid flow to reduce the build-up of contaminants on
the seat. An elastomeric diaphragm regulator with a valve
actuator coupled to a guided valve stem attached to the
regulator diaphragm.
Patent EP-1043882-A2 (EP)
Inventor: MORITA YUUKICHI
IPC: H04N1/00
Filed: 2000-04-07
Abstract: An automatic-paper-feed-type document scanning
mechanism is disposed on flat-bed-type document scanning
mechanism and discharges documents onto the document holding
cover of the flat-bed-type document scanning mechanism. The
document holding cover includes a groove formed in the
document holding cover and a stopper member fitted therein.
The groove extends in the document transport direction and
has a first engagement portion on its side wall. The
stopper member has a base portion which has a second
engagement portion that can be engaged with the first
engagement portion and can be moved along the document
transport direction while being guided by the groove, and a
vertical portion projecting perpendicular from the base
portion.
Patent EP-1027866-A2 (EP)
Inventor: ZLOCK STEPHEN W
IPC: A61B17/06
Filed: 1994-10-06
Abstract: Mechanism (45) for use in loading an elongate surgical
incision member (14) having opposite ends (55, 56)
connection by a shaft portion into a surgical apparatus
having opposed jaws which exhibit an open configuration
such that each of the opposite ends is in registry with a
different one of the opposed jaws, the mechanism
comprising: a body portion; a member which defines notch
(44) in which the shaft portion is received, thereby to
attach said surgical incision member to said loading
mechanism; a pair of first recess (42, 43) flanking the
notch and into which said opposed jaws may be inserted
when in their open configuration, so as to bring each jaw
into registry with a different one of the opposite ends
of the incision member and a single second recess (49) in
line with the notch (44) from which said jaws in the
closed configuration may be removed from the mechanism
containing the incision member between the jaws.
Patent EP-1058268-A2 (EP)
Inventor: OGIWARA RYU
IPC: G11C11/22
Filed: 2000-06-02
Abstract: A chain type ferroelectric random access memory
has a memory cell unit comprising ferroelectric memory
cells (M0-M7) electrically connected in series to each
other, a plate line (PL〈0〉) connected to an electrode
of the memory cell unit, a bit line (BL) connected to
the other electrode of the memory cell unit via a
switching transistor (QB0), a sense amplifier (SA)
which amplifies the voltages of this bit line and its
complementary second bit line, and a transistor (QS)
inserted between the switching transistor and the sense
amplifier, and that a value (VPP1), being the minimum
value of the gate voltage in the transistor (QS)
obtained during elevation of the plate line voltage and
comparative amplification, is smaller than a value
(VPP2), being the maximum value of the gate voltage in
the transistor (QS) obtained during fall of the plate
line voltage and comparative amplification. With these
features, decrease in the accumulated charge of
polarization in the memory cell is reduced and
occurrence of disturb is prevented during read/write
operations.
Patent EP-1081273-A2 (EP)
Inventor: FEHL HANS
IPC: D06N7/00
Filed: 2000-06-30
Abstract: The electrically conductive elements (4) are guided through the bottom layer (3). The conductive elements (4) are nails or clips. The covering is fixed to a floor with a conductive adhesive via its bottom layer (3), and the conductive top layer (2) consists of a pile.
Patent EP-1103831-A2 (EP)
Inventor: YAP DANIEL
IPC: G02B6/42
Filed: 2000-10-19
Abstract: An application-specific rf optoelectronic integrated circuit (10)
having a generic chip (12) and a defining substrate (14) in
communication with at least one generic chip (12). The generic chip (12)
contains passive building block components (18,20,22,24,26) that are
independent from each other and being connected by paths external to the
generic chip member (12). The external connection paths are defined on
the substrate (14) having passive components and providing optical and
electrical interconnection. It is possible to use the same design of the
generic chip (12) for several applications merely by altering the
interconnect paths on a defining substrate (14). The optical
interconnection is made by optical fibers positioned in V-grooves. The
generic chip is flip-chip mounted using solder bumps.
Patent EP-1103782-A2 (EP)
Inventor: DEGEN MARTIN
IPC: G01D5/26
Filed: 2000-11-17
Abstract: The method in which light from a light-source is fed into light conductors (4, 5) that serve to damp the light from the light source. A light coupling element (9) that corresponds to the position of a moving member (2) returns the light to a detector. The amount of damping of the light can then be used to determine moving member position. An Independent claim is also included for an optical sensor for position determination of a moving member or element.
Patent EP-1120144-A2 (EP)
Title: Spielfahrzeug mit verstellbarer Magnethaftung
Inventor: MALEIKA HUBERTUS
IPC: A63H18/16
Filed: 2000-12-29
Abstract: Die Erfindung betrifft ein Spielfahrzeug mit feststellbarer Magnethaftung für eine Autorennbahn mit in die Fahrbahn eingelassenen ferromagnetischen Stromleitern, die mit einem im Chassis (2) des Spielfahrzeugs eingelassenen Dauermagneten (3, 3A) in Wirkverbindung stehen, wobei der Dauermagnet (3, 3A) im Chassis entlang einer schiefen Ebene zur Einstellung des Abstandes zwischen Dauermagnet und Stromleitern verschiebbar ist. Erfindungsgemäß ist der Dauermagnet (3, 3A) entlang einer gegenüber der Fahrbahnebene schräg verlaufenden ferromagnetischen Halteplatte (9, 10) verschiebbar, welche in einer einstückig mit dem Chassis (2) ausgebildeten Aufnahme (5) aufgenommen ist, wobei die Unterseite der Aufnahme (5) zwei Führungsschienen enthält, entlang der der Dauermagnet verschiebbar ist. <IMAGE>
Patent EP-1089270-A2 (EP)
Inventor: DE BRUIJNE ROELAND PIETER PROF
IPC: G11B7/28
Filed: 2000-09-25
Abstract: The discs are held in a magazine (5) and are transferred to and from a drive unit that allows information to be read and written onto disc. A disc containing information to be copied (4) is read by an optical unit (7) and the data entered into a memory buffer (10). The data is then copied onto a magazine disc (6)
Patent EP-1111692-A2 (EP)
Inventor: ACKERMANN BERND DR
IPC: H04N5/222
Filed: 2000-12-12
Abstract: An actuator has multiple piezo-electrical driving mechanisms (1a-1c) and a sphere (2) with a video camera (3) rotating around two or more axes of rotation (7a-7c). A structure transmits images and sound from the actuator. The piezo-electrical driving mechanisms can turn the sphere in a random manner and can use friction through oscillations in a tangential direction.
Patent EP-1095722-A2 (EP)
Inventor: LEADER JOHN MICHAEL
IPC: B23B31/163
Filed: 2000-10-23
Abstract: A novel stationary comprises top jaws 21 each carried by base jaw 7 which in
turn is carried on a chuck body 2 which sits on the chuck base 3. In the base 3 is a
gearing system comprising a pinion 13 which meshes with a cam gear 6. The cam gear
6 carries slots that accept load pins 4 which are fixed to and carried by the base jaws
7. The load pins 4 mate with recesses in the under surface of the top jaws 21. The
pinion 13 has a recess in its upper surface for receiving a turn key to turn the pinion
and activate the gearing system. To close the chuck, a turn key is inserted into the
pinion 13 and the pinion is rotated. Meshing cam gear 6 is caused to rotate
simultaneously. As the cam gear rotates, the load pin travels in the slot 31 between the
radially outermost portion of the slot and the radially innermost portion of the slot.
The load pin 4 which is constrained from moving in an arcuate motion is forced to
travel radially inward of the front plate 1 of the chuck carrying with it the top jaw 21.
The chuck provides a compact, efficient and effective alternative to conventional scroll
operated chucks.
Patent EP-1096496-A2 (EP)
Inventor: MCMURDIE MICHAEL SCOTT
IPC: G11B27/034
Filed: 2000-10-31
Abstract: Methods and apparatus for the recording of data to an optical media are provided.
In one example, a method includes the selection of data to be recorded by a client
application. After interface with an image mastering application programming interface,
the selection of an optical media format, and the selection of an optical media recording
device, the selected data is sent to a stash file. A task list of operations to be performed in
the recording of the selected data is created, and the data is recorded by executing the task
list from Kernel Mode of an operating system. In another example, an image mastering
application programming interface is provided. The image mastering application
programming interface is a collection of COM objects including a disk master, a stash
file, a disk recorder, and a burn engine. In another example, a computer readable media
having program instructions for the recording of data to an optical media is provided.
The program instructions enable the selection of data, sending the data to a stash file,
creating a task list for the recording of the data, and executing the task list from Kernel
Mode of an operating system.
Patent EP-1111266-A2 (EP)
Inventor: TOURNIER PASCAL
IPC: F16F9/06
Filed: 2000-12-21
Abstract: A hydraulic cylinder comprising cylinder means (2), a piston rod (6) extending
through a first end of the cylinder means (2), and a piston (4) carried by the piston rod
(6) and sealingly slidable in the cylinder means (2), the piston (4) dividing the cylinder
means (2) into a first fluid-filled chamber (18) containing the piston rod (6), and a
second fluid-filled chamber (20), the piston (4) including first and second valves each
having a valve closure (28,42) sealable against respective valve seats (36,48) formed
in the piston (4), each valve being operable to allow fluid flow in respectively opposite
directions between the first and second chambers (18,20) in response to a pressure
differential between the two chambers (18,20) and each closure (28,42) including a
portion of magnetic material (34,44) such that each valve is biassed into a closed
position by magnetic attraction between the valve closure (28,42) and the respective
valve seat (36,48).
Patent EP-1204759-A2 (EP)
Inventor: SCOTT RODERICK JOHN
IPC: C12N15/82
Filed: 2000-07-31
Abstract: A method for controlling endosperm size and development in plants. The method employs nucleic acid constructs encoding proteins involved in genomic imprinting, in the production of transgenic plants. The nucleic acid constructs can be used in the production of transgenic plants to affect interspecific hybridisation.
Patent EP-1255856-A2 (EP)
Inventor: KINZLER KENNETH W
IPC: C12N15/09
Filed: 2000-07-31
Abstract: The identification of pre-defined mutations expected to be present in a minor fraction of a cell population is important for a variety of basic research and clinical applications. The exponential, analog nature of the polymerase chain reaction is transformed into a linear, digital signal suitable for this purpose. Single molecules can be isolated by dilution and individually amplified; each product is then separately analyzed for the presence of pre-defined mutations. The process provides a reliable and quantitative measure of the proportion of variant sequences within a DNA sample.