baber/WOPTO huggingface dataset:
Patent CA-3106948-A1 (CA)
Inventor: BAI JIRONG
IPC: G01N33/50
Filed: 2019-08-09
Abstract: GFRAL extracellular domains comprising domains D2 and D3 are disclosed. The disclosure further relates to methods and compositions for screening and evaluating the activity of a GFRAL ligand, such as a GDF15 peptide, using the GFRAL extracellular domains provided herein. Also disclosed are methods and compositions for treating obesity, reducing appetite, and/or reducing body weight using the GFRAL extracellular domains provided herein.
Patent CA-3107205-A1 (CA)
Title: Process for producing hydrocarbons from a hydrocarbon-bearing reservoir
Inventor: CHHINA HARBIR SINGH
IPC: E21B43/24
Filed: 2021-01-26
Abstract: A process for producing hydrocarbons from a subterranean hydrocarbon-bearing reservoir, includes injecting steam via an injection well into the hydrocarbon-bearing reservoir and producing fluids from the hydrocarbon-bearing reservoir to a surface through a production well, to develop a steam chamber within the hydrocarbon-bearing reservoir. The process also includes injecting both steam and oxygen through the injection well and into the hydrocarbon-bearing reservoir to mobilize the hydrocarbons while controlling a rate of steam injection and controlling a rate of oxygen injection to maintain liquid water in the reservoir and facilitate low temperature oxidation. Production of fluids including mobilized hydrocarbons is from the reservoir is continued and a pressure substantially corresponding to a steam saturation pressure at a temperature in the reservoir is maintained to facilitate the low temperature oxidation.
Patent CA-3108150-A1 (CA)
Title: Methods for treating neurodegenerative disorders
Inventor: HEY JOHN
IPC: A61K31/185
Filed: 2019-07-30
Abstract: Tramiprosate and derivatives thereof are provided herein for treating neurodegenerative disorders such as Alzheimer's disease (AD).
Patent CA-3108192-A1 (CA)
Title: Novel mhc-independent tumor-associated antigens
Inventor: SCHADENDORF DIRK
IPC: C12N15/12
Filed: 2013-12-16
Abstract: ABSTRACT The present invention relates to novel tumor-associated antigens, which elicit independently from a presentation via MHC a CD8-positive T-cell response. GM-CSF-Receptor alpha chain (CSF2RA) and Tyrosinase-related protein 2 (TRP-2) were found to be targets of CD8-positive T-cell clones which could detect the proteins on the surface of EILA  I negative melanoma cells. Thus, the invention provides proteins, protein fragments and polypeptides of the novel antigens for use in medicine, for example for the treatment, diagnosis and prevention of a tumor disease. Furthermore provided are nucleic acids expressing the antigens of the invention, binding agents specific for the antigens of the invention, such as T-cell receptor chains and isolated T cells which are reactive against the antigens of the invention or which express the T-cell receptors of the invention. The invention further pertains to pharmaceutical compositions, especially vaccine compositions, comprising the antigens, nucleic acids, binding agents or T  cells in accordance with the invention, and methods for the generation of T cells, which are specifically reactive to the antigens of the invention in an MHC-independent manner. Date Recue/Date Received 2021-02-08
Patent CA-3109440-A1 (CA)
Inventor: PRAMANICK SOUGATA
IPC: A61K31/17
Filed: 2019-09-03
Abstract: The present invention relates to a ready-to-use solution of carmustine that does not require dissolution or dilution of the carmustine prior to addition to saline and dextrose parenteral solutions. In particular, the invention relates to a stable liquid pharmaceutical composition containing carmustine in the form of ready-to-use solution and method for preparing the same.
Patent CA-3110655-A1 (CA)
Title: Dispositifs et methodes de systeme de drainage oculaire
Inventor: ROEBER PETER J
IPC: A61F9/00
Filed: 2019-08-29
Abstract: L'invention concerne des systèmes de drainage oculaire. Dans divers modes de réalisation, les systèmes de drainage oculaire comprennent un conduit de fluide souple qui est conçu pour être implanté dans un tissu biologique, tel que des tissus d'un il. Le conduit de fluide souple comprend un extérieur ayant une microstructure qui est conçue pour permettre une interposition cellulaire. Une première extrémité du conduit de fluide souple est conçue pour être insérée dans un il d'un patient pour permettre au liquide oculaire d'être drainé de l'il, et une seconde extrémité du conduit de fluide souple est conçue pour être insérée dans un système veineux oculaire du patient pour permettre au liquide oculaire drainé de l'il de s'écouler directement dans le système veineux oculaire.
Patent CA-3111251-A1 (CA)
Inventor: BIJL DARRELL
IPC: E02D13/04
Filed: 2021-03-04
Abstract: An alignment tool for a pile cap is disclosed, wherein the alignment tool comprises: a tensioner configured to apply tension to a cord; a pile cap fastener coupled to the tensioner;  and a cord guide coupled to the fastener; wherein the cord guide is configured to guide a cord under tension by the tensioner.
Patent CA-3111606-A1 (CA)
Title: Tethered plastic stopper
Inventor: GRABARCZYK HENRI
IPC: B65D47/08
Filed: 2019-09-23
Abstract: The present invention relates to tethered plastic stopper having a tamper band having an offset wall, a closure shell having a peripheral wall, and a hinge connected to the closure shell and a bottom edge attached to the tamper band. The closure shell is also separably connected to the tamper band through a weakness line. The peripheral wall extends around a portion perimeter of the stopper forming a first end at one edge of the peripheral wall and a second end edge at the other edge of the peripheral wall. The offset wall extends between the first and second ends of the peripheral wall at the opposite of the hinge.
Patent CA-3114829-A1 (CA)
Title: Method for fixing a rail of a rail track with thermal conditioning of a rail portion, and associated rail machine
Inventor: SAVOYAT MARC-ANTOINE
IPC: E01B29/17
Filed: 2019-10-01
Abstract: In order to fix a rail (12) of a rail track using a rail machine (4), the rail machine (4) is moved in a working direction (100) so that at all times a rail portion (12) which is not attached to a cross-member (8, 10) of the rail track (2) passes through a thermal conditioning zone (30) of a thermal conditioning device (32) of the rail machine (4), a temperature of a surface region of the rail portion passing through the thermal conditioning zone (30) is modified using the thermal conditioning device (32) by generating a non-homogeneous temperature distribution in the rail portion, and the rail portion (12) is fixed to a cross-member (10) of the rail track, after modification of the temperature of the surface region of the rail portion, without waiting for the temperature distribution in the rail portion to be homogenised.
Patent CA-3115067-A1 (CA)
Title: Ultrasonic interventionless system and method for detecting downhole activation devices
Inventor: KALB FRANK D
IPC: E21B47/18
Filed: 2019-10-07
Abstract: An mterventionless system and method: of detecting a downhole activation device are provided. The system includes a first detector disposed downhole in a fluid pathway and;a second detector disposed downhole of the first detector in the fluid pathway. In one exemplary embodiment, the detectors include a pair of ultrasonic transducers that generate signals indicative of fluid pathway flow. Differences in the signals between the detectors are indicative of the presence of the downhole activation device within the fluid pathway. The system also includes a deployment port disposed above the second detector from which the downhole activation device may be deployed into the fluid pathway.
Patent CA-3115080-A1 (CA)
Title: Slicing machines and methods for slicing products
Inventor: KING DANIEL WADE
IPC: B26D7/26
Filed: 2019-10-03
Abstract: Machines and methods for slicing products into lattice-type slices or chips. The methods and machines utilize a cutting head having an annular shape that defines an axis of the cutting head, and an impeller assembly coaxially mounted within the interior of the cutting head for rotation about the axis of the cutting head. The cutting head having at least one knife at a perimeter thereof and extending radially inward of the cutting head. The impeller assembly has a base, a cavity within the base, a central opening to the cavity within the base, and equi-angularly spaced tubular guides extending radially outward from the base for delivering products within the cavity toward the perimeter of the cutting head as the impeller assembly rotates within the cutting head. The impeller assembly includes features with the ability to increase product throughput and increase the useful lives of the impeller assembly and cutting head.
Patent CA-3115319-A1 (CA)
Inventor: BRIGHAM GRAHAM
IPC: F16L55/17
Filed: 2021-04-15
Abstract: ABSTRACT A flange belt has a flexible belt with a flexible metal insert sheathed within it that allows the flange belt to conform to a flanged joint when the flanged belt is wrapped around it. The flexible belt has a first longitudinal channel and a second longitudinal channel. A first band and a second band are sized to fit within the first longitudinal channel and the second longitudinal channel, respectively. The first band and the second band are used to hold the flexible belt on the flanged joint. 8 Date Recue/Date Received 2021-04-15
Patent CA-3116239-A1 (CA)
Inventor: LI XIANG
IPC: B60G7/04
Filed: 2021-04-27
Abstract: Un dispositif de suspension et un véhicule tout-terrain sont décrits. Le dispositif de suspension comprend : un premier culbuteur comprenant une première extrémité possédant une partie de limitation de première position; un deuxième culbuteur espacé du premier culbuteur; et une fusée dessieu placée entre la première extrémité du premier culbuteur et le deuxième culbuteur. La fusée dessieu est raccordée à la première extrémité du premier culbuteur et à une première extrémité du deuxième culbuteur, et comprend une partie de limitation de troisième position configurée pour être ajustée avec la partie de limitation de première position. La partie de limitation de troisième position est configurée pour être jouxtée à la partie de limitation de première position lorsque la fusée dessieu est déplacée à une première position de hauteur extrême et le véhicule tout-terrain comprend un premier angle de braquage maximum.
Patent CA-3116853-A1 (CA)
Title: Methods of treating cns tumors with tesetaxel
Inventor: JAMES JOYCE
IPC: A61K31/357
Filed: 2019-09-05
Abstract: The present disclosure provides methods for treating a patient with a cancer in the central nervous system, such as a cancer that is a metastasis of a primary cancer, comprising administering tesetaxel and capecitabine to the patient.
Patent CA-3117030-A1 (CA)
Title: Methods for generating therapeutic delivery platforms
Inventor: HE MEI
IPC: G01N33/00
Filed: 2019-10-21
Abstract: Methods for producing engineered exosomes and other vesicle-like biological targets in a microfluidic device, including allowing a target vesicle-like structure to react and bind with immunomagnetic particles; capturing the immunomagnetic particle/vesicle complex by applying a magnetic field; further engineering the captured vesicles by surface modifying with additional active moieties or internally loading with active agents; and releasing the engineered vesicle-like structures, such as by photolytically cleaving a linkage between the particle and engineered vesicle-like structures, thereby releasing intact vesicle-like structures which can act as delivery vehicles for therapeutic treatments.
Patent CA-3118458-A1 (CA)
Inventor: SHAFIEE HADI
IPC: G01N33/483
Filed: 2019-11-01
Abstract: A system comprises: an optical assembly comprising at least one lens and having an associated axis; a microfluidic device comprising a channel to hold a fluid sample from a subject and a reservoir for receiving the fluid sample, the channel being configured to receive a smearing block that spreads a thin film of the fluid sample across the channel, and the microfluidic device being configured to engage with a housing such that the channel is aligned with the axis of the optical assembly; a camera aligned with the axis of the optical assembly; a processor; and a non-transitory computer readable medium storing executable instructions for providing at least one image captured at the camera to a computer vision model implemented as a convolutional neural network comprising: a plurality of convolutional layers to determine if there is a ferning pattern representative of a biological condition of the subject in the at least one image.
Patent CA-3119899-A1 (CA)
Title: Retail merchandise shelving system and deck panels for same
Inventor: SMEDLEY JAMIE A
IPC: A47F5/00
Filed: 2021-05-27
Abstract: A deck panel for a retail shelving system is provided. The deck panel includes a panel and a region of strengthening ribbing. The panel has a top surface configured for supporting retail merchandise and a bottom surface. The region of strengthening ribbing includes a plurality of ribs extending outward from the bottom surface of the panel. The bottom surface of the panel has a border region that extends around the region of strengthening ribbing on at least three sides. The deck panel may be part of a shelf which may be part of a shelving system.
Patent CA-3122667-A1 (CA)
Inventor: RODRIGUEZ-VILLEGAS ESTHER
IPC: A61B5/00
Filed: 2019-12-13
Abstract: The present invention relates to apparatus for measuring physiological parameters in a blood vessel. The apparatus comprises at least one acoustic sensor positionable on a part of a subject's body which is configured to receive an acoustic signal from a target blood vessel. The acoustic sensor is attached to the part of the subject's body by an attachment means.
Patent CA-3123019-A1 (CA)
Title: Server-assisted routing in network communications
Inventor: WOODLAND BERNARD M
IPC: H04L45/42
Filed: 2019-12-16
Abstract: A network node device and method of determining a communication route to one or more other network nodes through a network. The method includes sending current routing information to a network management server (NMS), and receiving new or supplemental routing information from the NMS, this supplemental routing information determined by the NMS based on the current routing information of the network node and of the one or more other network nodes. The supplemental routing information may include lateral route information identifying designated routing nodes that form lateral band(s) of nodes that span the network, each lateral band including gate node(s) as entrances/exits to the lateral band. The method may further include determining, based on the supplemental routing information, a route to one or more of the other network nodes. A lateral band may facilitate a route through a chokepoint or other abnormal topological layout.
Patent CA-3123129-A1 (CA)
Title: Laser lowering device
Inventor: ROCHELEAU DARYL
IPC: H01S5/02315
Filed: 2021-06-04
Abstract: A laser lowering device for mounting a laser, which in one embodiment includes: at least one laser support for mounting the laser; a mount having a line receiving portion, the mount being connected to the at least one laser support; an elongated member having a first end and a second end, the first end being removably connected to a pole and the second end being pivotally connected to the mount;  and a mount control line connected to the line receiving portion and extending towards the elongated member. The mount control line is manipulable to cause the mount to pivot relative to the elongated member.The laser lowering device allows a laser to be remotely lowered into a non-traditional manhole and inserted into pipes.
Patent CA-3126755-A1 (CA)
Inventor: HARFOUCHE JOSEPH
IPC: G01B3/10
Filed: 2020-02-06
Abstract: The present invention relates to a device for measuring the circumference of an object, in particular to a device for measuring the circumference of a body limb.
Patent CA-3127287-A1 (CA)
Title: Single primary loop, dual secondary loop hydronic hvac system and methods of operation
Inventor: WESTON JEFFREY A
IPC: F28D1/04
Filed: 2020-04-06
Abstract: A hydronic system is provided that includes a primary fluid loop that includes a thermal source for heating or cooling a working fluid, dual secondary fluid loops that include respective thermal loads, and a decoupler. One leg of a supply tee at an output of the source places the output in fluid communication with one end of a decoupler and, beyond the decoupler, with the input of a thermal load of a first secondary fluid loop. Another leg of the supply tee places the source output in fluid communication with the input of a thermal load in a second secondary fluid loop. One leg of a return tee at an input of the source places the input in fluid communication with the other end of the decoupler and, beyond the decoupler, with the output of the thermal load of the first secondary fluid loop. Another leg of the return tee places the input of the source in fluid communication with the input of the thermal load in the second secondary fluid loop.
Patent CA-3129723-A1 (CA)
Title: Panel interlocking device
Inventor: HETTINGER PETER
IPC: B65D71/38
Filed: 2020-02-06
Abstract: Aspects of the disclosure relate to a panel interlocking device, a carton, and a blank for forming the carton. The carton blank incorporating a panel interlocking device for securing together a first and a second panel in overlapping relationship. The panel interlocking device comprises a locking tab struck from the first panel, and a retaining tab defining a locking aperture struck from the second panel. In use the retaining tab is displaced out of the plane of the second panel to receive said locking tab through the locking aperture to be engaged therewith. The retaining tab has opposing side edges each concavely curved as viewed from the outside of the retaining tab.
Patent CA-3129991-A1 (CA)
Inventor: ROBINSON RONALD LESLIE
IPC: F16F9/10
Filed: 2021-09-03
Abstract: The bearing assembly can extend between a rotor and a housing, have a plurality of bearing rolling elements mounted for rotation within a bearing ring, an oil damper cavity between the bearing ring and the housing, an oil inlet path to feed the oil damper cavity, and at least one damper ring defining a corresponding axial limit to the oil damper cavity and having a radially inner edge received in a corresponding annular groove defined in the bearing ring, and a radially outer edge having at least one arc portion extending radially outwardly relative the annular groove and engaging the housing, and at least one controlled leakage portion radially recessed from the housing and forming a leakage path leading axially out from the oil damper cavity.
Patent CA-3131044-A1 (CA)
Inventor: MOLLER PER
IPC: A47K10/36
Filed: 2019-03-11
Abstract: La présente invention concerne un insert de distributeur (1) destiné à être monté dans une armoire existante (2), l'insert de distributeur (1) comprenant un cadre (3) conçu pour être monté dans l'armoire (2), un mécanisme de distribution monté sur le cadre (3), le mécanisme de distribution comprenant une partie magasin (4) destinée à recevoir une pile de produits en feuilles et une partie de distribution (5) destinée à distribuer les produits en feuilles, la partie magasin (4) présentant un accès de remplissage (6) au niveau de sa partie inférieure, la partie de distribution (5) étant mobile au moins en translation par rapport à la partie magasin (4) jusqu'à une position de remplissage.
Patent CA-3132456-A1 (CA)
Inventor: WEEKES TERIK
IPC: B64D1/08
Filed: 2020-04-11
Abstract: A modular aerial cargo aerodynamic encasement and a method for modular aviation cargo transport is provided. The aviation cargo aerodynamic encasement comprises a platform having a planar upper surface configured to accept cargo and a lower surface. The lower surface includes two or more ground supports displacing a portion of the platform from contact with a supporting surface. The platform includes two or more load transfer structures. The aviation cargo aerodynamic encasement further comprises a fairing configured to detachably couple to the platform, wherein the fairing, when coupled to the platform, forms an aerodynamic encasement, and wherein the aerodynamic encasement is detachably mountable to an aircraft by the two or more load transfer structures.
Patent CA-3133140-A1 (CA)
Inventor: ZORN MARCEL
IPC: E04F15/02
Filed: 2020-02-24
Abstract: The present invention relates to a hard flooring panel with a top side and a bottom side and side edges along the panel sides, for laying in a floating manner to form a flooring panel composite, at least two flooring panels being joined together in each case, the opposing side edges being provided with tongue-and-groove profiles, a tongue and a joining face being provided in a first side edge, and a groove and a joining face being provided in a second, opposite side edge, the tongue of the first side edge having an upper side and a lower side; wherein a protrusion having a contact face is provided on the lower side of the tongue; wherein the joining face of the first side edge runs from the top side of the flooring panel towards the upper tongue side, and the joining face is chamfered; wherein the groove in the second side edge has a top side and a bottom side, the top side of the groove being delimited by an upper lip, and the bottom side of the groove being delimited by a lower lip; wherein a cut-out having a contact face is provided in the lower lip of the groove; wherein the joining face of the second side edge runs from the top side of the flooring panel along the upper lip, and the joining face is chamfered; wherein, when at least two flooring panels are joined together, the protrusion of the tongue engages in the cut-out in the lower lip of the groove so that the contact faces of the protrusion of the tongue and of the cut-out in the lower lip of the groove exert a clamping force on each other; and wherein, when the chamfered joining faces of the first side edge of the tongue profile and the chamfered joining face of the second side edge of the groove profile bear against each other in the joined together state of at least two flooring panels, a linear pressure is produced along the chamfered joining faces of the side edges of the tongue profile and of the groove profile.
Patent CA-3138603-A1 (CA)
Title: A computer-enabled method, system and computer program for providing an intuitive user interface arranged to create a dynamic floor plan utilisable by an allocation algorithm to perform the task of allocating a space, furniture, equipment or service
Inventor: PETROULAS PETER
IPC: G06Q50/12
Filed: 2020-04-28
Abstract: In one embodiment, there is provided a computer-enabled method for creating a volumetric space/time framework of constraints for the dynamic allocation of a booking request to one or more spaces in a venue. In one embodiment, the invention is directed to a computer-enabled method including a user interface accessible via a remote device such as a Point of Sale device, wherein the Point of Sale device is arranged to receive an interactive, real-time, dynamic floor plan including allocated and unallocated bookings, table numbers, chair position numbers and interact with a restaurant operator or operators.