baber/WOPTO huggingface dataset:
Patent IL-76762-A0 (IL)
Title: Autonomous replication sequences for yeast strains of the genus pichia
IPC: C12N15/00
Filed: 1985-10-20
Abstract: Novel autonomous replication sequences which are capable of maintaining plasmids as extrachromosomal elements in host strains of the genus Pichia are provided. In addition, novel constructs including these DNA sequences, as well as transformed organisms therewith are provided. Processes for producing the DNA sequences and constructs of the invention, as well as method for isolating such sequences from any source, are provided.
Patent IL-81675-A0 (IL)
Title: 1-arylpyrazoles,their preparation and their use as pesticides
IPC: C07D231/38
Filed: 1987-02-25
Abstract: Insecticidally and acarididally active 1-arylpyrazoles of the formula <IMAGE>   in which R1 represents hydrogen, alkyl or halogen alkyl, R2 represents alkyl, alkenyl, alkinyl, cycloalkyl, halogenoalkyl, halogenoalkenyl, alkoxyalkyl, alkylthioalkyl, alkylsulphinylalkyl, alkylsulphonylalkyl, optionally substituted aralkyl or optionally substituted aryl, R3 represents alkyl, alkenyl, alkinyl, halogenoalkyl, halogenoalkenyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl or optionally substituted aralkyl, R4 represents alkyl, alkenyl, alkinyl, halogenoalkyl, halogenoalkenyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl or optionally substituted aralkyl, and, in addition, also represents hydrogen in the case where R3 does not simultaneously represent unsubstituted alkyl, or R3 and R4, together with the nitrogen atom to which they are bound, represent a saturated heterocycle, which can optionally contain further heteroatoms, Ar represents in each case optionally substituted phenyl or pyridyl, and n represents a number 0, 1 or 2.
Patent IL-82118-A0 (IL)
Title: Process for recovery of glycopeptide antibiotics
IPC: C07K9/00
Filed: 1987-04-06
Abstract: This invention concerns the recovery of glycopeptidic antibiotics from aqueous solutions resulting from fermentation broths or process streams. Examples of glycopeptidic antibiotics to which the process of this invention may be applied are the following: vancomycin, actaplanin, ristocetin, avoparcin, actinoidin, LL-AM-374, A 477, OA 7653, A 35512 B, A 515668, AAD 216, A 41030, A 47934, A-40926 (European Pat. Appln. No. 85112406.5), the individual factors, derivatives and pseudo-aglycones and aglycones thereof, teicoplanin and teicoplanin-like compounds.
Patent IL-83243-A0 (IL)
Title: Peptides,pharmaceutical compositions containing them and their preparation
IPC: C07K14/575
Filed: 1987-07-20
Abstract: Insulin derivatives of the general formula I <CHEM> and having a charge which is positive compared with the charge of human insulin at neutral pH, can be used to prepare solutions having prolonged insulin action. In the novel insulin derivatives, a basic amino acid has been substituted in the B27-position and/or a neutral amino acid has been inserted in the A4-, A17-, B13- and/or B21-position. The C-terminal of the A-chain, Asn<A21>, may be substituted by another amino acid in order to increase the stability of the solutions at the slightly acidic pH of pharmaceutical solutions. Furthermore, the C-teminal carboxyl group of the B-chain may be blocked with an amido or ester residue. Provided that A21 is Asn, the carboxylic acid group of B30 is free.
Patent IL-85979-A0 (IL)
Title: Process for the manufacture of a fibre strengthened-moulded article for pipelines
IPC: B29C70/06
Filed: 1988-04-05
Abstract: A method of manufacturing a fiber-reinforced shaped article of plastics material for pipeline systems. The article includes an inner casing of a thermoplastic material and an outer casing of a fiber winding impregnated with resin. The tape is wound onto the inner casing so that at least the entire surface thereof is covered. The article is then immersed in a resin bath while a negative pressure is maintained outside of and in the interior of the article. The resin bath is subsequently subjected to atmospheric pressure. The impregnated article is removed from the resin bath and the resin is hardened by ultraviolet light while the article is simultaneously rotated.
Patent IL-92170-A0 (IL)
Title: Serineprotease inhibitor proteins,pharmaceutical compositions containing them,dna sequences coding for these proteins and the preparation of these proteins and dna sequences
IPC: A61P1/00
Filed: 1989-10-31
Abstract: The invention relates to serine protease inhibitor proteins, medicaments containing them, DNA sequences coding for these proteins and methods for producing these proteins, medicaments and DNA sequences. These proteins correspond to the formula <IMAGE> or sections thereof which comprise at least the sequence of positions 53-101, in which W is tyrosine or glutamic acid, X1, X2 and X3 are identical or different and each of these radicals is methionine or leucine, it also being possible for X3 to be phenylalanine, Y is proline or arginine, and Z is leucine or, if W is tyrosine and X1, X2 and X3 are leucine, is also isoleucine, and fusion proteins of these serine protease inhibitor proteins. The proteins are particularly distinguished by a strong inhibitory action against human leukocyte elastase and pronounced stability to oxidative breakdown. DNA sequences which code for the serine prolease inhibitor proteins and the expression of these proteins in suitable host organisms by means of various vectors, and the isolation of these proteins in pure biologically active form, and medicaments containing these products, are described. <IMAGE> (Oligonucleotid = oligonucleotide> Figure 1a: DNA oligonucleotides D11, D12, D13, D11a, D12a and D13a (listed in the 3'->5' direction of synthesis) which are used in the synthesis of the DNA sequence "ALP gene 230" (Figure 2a). <IMAGE> Figure 1b: DNA oligonucleotides D21, D22, D23, D21a, D22a and D23a (listed in the 3'->5' direction of synthesis) which are used in the synthesis of the DNA sequence "ALP gene 230" (Figure 2a). <IMAGE> Figure 1c: DNA oligonucleotides D24, D25, D24a and D25a (listed in the 3'->5' direction of synthesis) which are used in the synthesis of the DNA sequence "ALP gene 240" (Figure 2b) commencing from the DNA sequence ALP gene 230.
Patent IL-97271-A0 (IL)
Title: Pharmaceutical compositions having depigmentating and antiphotoageing activity
IPC: A61K8/00
Filed: 1991-02-18
Abstract: The object of the present invention is a product based on a trans-retinoic acid (tretinoin) and azelaic acid combination having depigmentating effect and, more generally, antiphotoageing effect. After clinical and instrumental comparative analysis (clinical and photographic reports and skin mould profilometry), the action on physiological and/or photoinduced skin ageing obtained with the combination of the invention has been compared with the one noticeable after the treatment with azelaic acid or retinoic acid only. Better results were obtained using the azelaic-retinoic combination. The depigmentating action of the combination is superimposable to the one observed by using separately the two active ingredients, but it can be achieved in a surprisingly shorter time (from six to three months).
Patent FI-20002437-A0 (FI)
Inventor: TAIVALANTTI VESA
IPC: H04W88/16
Filed: 2000-11-07
Abstract: When a service is provided in a service stream between end devices controlling the service stream by using first protocol, there is also a need to control the service stream in the network via which the service stream is or is to be transmitted. The service stream is controlled in the network by utilizing first protocol messages which are separated (204) from other traffic transmitted in the network.
Patent FI-20002439-A0 (FI)
Inventor: VESTBERG TORVALD
IPC: C08F4/642
Filed: 2000-11-07
Abstract: The present invention concerns a propylene polymerization process comprising preactivating the catalyst in the presence of cocatalyst and external donor, preferably activating the preactivated catalyst by a cocatalyst and further possibly prepolymerizing the obtained catalyst and polymerizing propylene optionally together with other comonomers without adding any additional external donor after the preactivating step.
Patent FI-20012130-A0 (FI)
Inventor: HILLIAHO ERKKI
IPC: E06B3/92
Filed: 2001-11-05
Abstract: Hinging piece (15) of a glazing system, which, when installed in its place, is intended movable in the X direction when it is arranged in a guide profile (16) of the glazing system, to which the glasss panes (1) of the glazing system are intended to be suspended by means of said hinging piece (15) that comprises a horizontal set of wheels (17, 18) arranged on a rotation axis (19) extending in the Y direction and intended to support the hinging piece (15) on the guide profile (16); and a frame part (22) arranged to rotate around said rotation axis (19) with the glass panes. The frame part (22) comprises at least fastening means (36) for suspending the glass panes to the hinging piece (15); locking means (33) arranged for locking the hinging piece (22) is in a predetermined rotating position, said locking piece being attached to the adjacent hinging piece when two hinging pieces (15) are positioned successively, wherein the locking prevents the divergence of adjacent hinging pieces (15) from each other in the X direction; and bearing means (31) arranged for fastening a locking piece (14) to the frame part (22) in such a manner that the frame part (22) is capable of rotating around said rotating axis (19) in relation to the locking piece (14).
Patent IL-101379-A0 (IL)
Title: Light screening compositions containing isoxazolones,certain such novel compounds and their preparation
IPC: A61K8/49
Filed: 1992-03-26
Abstract: Light screening compositions which contain a compound of the formula    <IMAGE>  I  wherein R1 represents H, C1-19-alkyl, C2-29-alkenyl, C2-29-alkynyl, optionally lower-alkyl or oxy-lower alkyl substituted phenyl, R2 represents H, C1-29-alkyl, C2-29-alkenyl, C2-29-alkynyl, optionally lower-alkyl or oxy-lower alkyl substituted phenyl, R3 represents H, C1-19-alkyl, C1-19-hydroxyalkyl, C1-19-polyhydroxyalkyl, C2-29-alkenyl, C2-29-alkynyl, optionally lower-alkyl or oxy-lower alkyl substituted phenyl or optionally lower-alkyl or oxy-lower alkyl substituted pyridyl, a polyether residue, a phenylsulphonic acid residue and R2 and R3 together with the N atom can also form a ring.
Patent IL-105255-A0 (IL)
Title: Perhydroisoindole derivatives,their preparation and pharmaceutical compositions containing them
IPC: C07D403/06
Filed: 1993-04-01
Abstract: PCT No. PTC/FR93/00352 Sec. 371 Date Oct. 11, 1994 Sec. 102(e) Date Oct. 11, 1994 PCT Filed Apr. 8, 1993 PCT Pub. No. WO93/21155 PCT Pub. Date Oct. 28, 1993.This invention relates to novel perhydroisoindole derivatives of general formula (I),    <IMAGE>  (I)  wherein radicals R are phenyl radicals optionally 2- or 3-substituted by a halogen atom or a methyl radical; R1 is optionally substituted phenyl, cyclohexadienyl, naphthyl, indenyl or optionally substituted heterocyclyl; R2 is H, halogen, OH, alkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkyloxy, alkylthio, acyloxy, carboxy, optionally substituted alkyloxycarbonyl, benzyloxycarbonyl, amino or acylamino; R3 is optionally 2-substituted phenyl; R4 is OH or fluorine when R5 is H, or R4 and R5 are OH or R4 and R5 together form a bond; isomeric forms and mixtures thereof; optionally salts thereof where applicable; and preparation thereof. The novel derivatives are particularly useful as P substance antagonists.
Patent IL-105879-A0 (IL)
Title: Pharmaceutical compositions comprising taxol
IPC: A61K31/57
Filed: 1993-06-02
Abstract: The invention concerns products containing taxol for use in cancer therapy.According to this invention, the products contain an anti-neoplastically effective amount of taxol and sufficient medications to prevent severe anaphylactic-like reactions and are formulated and packaged for separate or sequential or simultaneous use in cancer therapy with a patient over a period of about 24 hours or less.These products find application in the treatment of all types of cancers, treatable by taxol.
Patent IL-113519-A0 (IL)
Title: Compounds and methods for inhibiting gene expression
IPC: C07H/
Filed: 1991-08-02
Abstract: The present invention relates to compounds, compositions and methods for inhibiting gene expression. The compounds of this invention comprise 1) oligonucleoside sequences of from about 6 to about 200 bases having a three atom internucleoside linkage or 2) oligonucleotide sequences of from about 9 to about 200 bases having a diol at either or both termini.
Patent IL-121001-A0 (IL)
Title: High strength internal bone fixation devices and process for forming same
IPC: A61L31/04
Filed: 1997-06-05
Abstract: Processes are set forth for forming high strength thermoplastic polymer bone fixation devices used, for example, in orthopedic surgery, where "strength" is quantified in terms a given device's pullout strength, tensile modulus, shear strength and breaking torque strength. Products of the aforementioned process are contemplated by the invention as well, with both "bioabsorbable" devices, for example, screws which are absorbable in an animal body and do not need to be removed after the bone in which they are inserted has healed; and non-bioabsorbable devices being described. <IMAGE>
Patent IL-121898-A0 (IL)
Title: A method and apparatus for active testing and fault allocation of communication networks
IPC: H04L12/26
Filed: 1997-10-07
Abstract: A method and apparatus for testing a network having a plurality of nodes. The method includes sending commands to one or more traffic agents connected to the network and to at least one network management agent coupled to a respective node of the network, transmitting data from at least one of the traffic agents over the network responsive to the commands, determining network information at the at least one network management agent responsive to the commands and to transmission of the data through the respective node, and receiving and evaluating the network information to assess a state of the network.
Patent IL-125136-A0 (IL)
Title: Electrical muscle controller
IPC: A61B18/20
Filed: 1997-01-08
Abstract: This invention is a method of modifying the force of contraction of at least a portion of a heart chamber, including providing a subject having a heart (30), comprising at least a portion having an activation; and applying a non-excitatory electric field (37) having a given duration at a delay after the activation to the portion, which causes the force of contraction to be increased by at least 5 percent. <IMAGE>
Patent IL-131594-A0 (IL)
Title: Diagnosis of early gastric cancer
IPC: G01N33/50
Filed: 1998-03-18
Abstract: The present invention pertains to a method for determination of the significance of a histologically detected premalignant lesion as a risk for intestinal type gastric cancer or carcinoma in situ, comprising detecting from a patient sample comprising gastric mucosa cellsa) cyclooxygenase-2 Cox-2) mRNA expression, orb) Cox-2 protein;wherein overexpression of Cox-2 is indicative of an increased risk for intestinal type gastric cancer.
Patent IL-133860-A0 (IL)
Title: Method for preparing substituted benzyl bromides
IPC: C07C205/11
Filed: 1998-07-20
Abstract: PCT No. PCT/EP98/04485 Sec. 371 Date Jan. 11, 2000 Sec. 102(e) Date Jan. 11, 2000 PCT Filed Jul. 20, 1998 PCT Pub. No. WO99/06339 PCT Pub. Date Feb. 11, 1999Substituted benzyl bromides of the formula I where at least one substituent R1-5 is an electron-attracting group such as fluorine, chlorine, bromine, C1-C4-alkoxycarbonyl, cyano or nitro, and the other substituents R1-5 are hydrogen or methyl, are prepared by bromination of substituted toluenes of the formula II with a brominating agent at from 20 to 95 DEG  C.
Patent IL-147961-A0 (IL)
Title: Stoma opening forming apparatus
IPC: A61B17/135
Filed: 2000-08-01
Abstract: In the treatment of morbid obesity or heartburn and reflux disease an elongated restriction member (12) is formed in a substantially closed loop around a human's stomach or esophagus to form a stoma opening in the stomach or esophagus. The size of the stoma opening is adjustable by an implanted adjustment device. A control device (22) is utilized to control the adjustment device, in order to either reduce or enlarge the size of the stoma opening, for example in response to the time of the day. Nausea in a treated obese human can be minimized or substantially eliminated as a result of the control device controlling the adjustment device to keep the stoma opening substantially fully open between meals (such as at night when the human is sleeping). A sensor (23), such as a pressure or position sensor, is surgically implanted in the human's body so that the sensor may either directly or indirectly sense a physical parameter of the human, such as the pressure in the stomach or the human's orientation with respect to the horizontal. If in response to sensing by the sensor it is determined by the control device that a significant change in the physical parameter has occurred, then the control device controls the adjustment device to either reduce or enlarge the size of the stoma opening.
Patent IL-150810-A0 (IL)
Title: A system for detecting substances
IPC: A61B1/05
Filed: 2001-01-18
Abstract: The present invention relates to a method and system for the in vivo determination of the presence and/or concentration of biological and/or chemical substances in body lumens. The system of the invention comprises a solid support, the support being inserted into a body lumen and having immobilized thereon at least one reactant capable of reacting with the substance resulting in an optical change; and a detecting unit, in communication with the support, capable of detecting a reaction resulting in an optical change between the reactant and the substance.
Patent IL-165946-A0 (IL)
Title: Potassium channel sub-units their preparation and use
IPC: C12N15/12
Filed: 2004-12-23
Abstract: The invention relates to the use of PP2A/Bgamma and to the use of a PP2A phosphatase comprising the PP2A/Bgamma subunit for screening for modulators thereof. The use of these modulators for treating mental disorders such as bipolar disorder, schizophrenia and depression, and drugs comprising these modulators are further disclosed. The invention also discloses biallelic markers located in the gene encoding PP2A/Bgamma and their use for diagnosing mental disorders.
Patent IL-184248-A0 (IL)
Title: Assay using marked microbial host cell strains
IPC: C12N1/21
Filed: 2007-06-26
Abstract: Presence of a contaminating microbial host cell (A), in a culture vessel containing a different host cell (B) able to use more than one carbohydrate (I), is detected by: (a) culturing (B), which includes nucleic acid encoding a particular polypeptide (II) and genetically marked so that it can not use a selected (I), (Ia), as substrate; (b) plating an isolated sample of the culture on a medium supplemented by (Ia); (c) incubating the plated cells, and (d) detecting if any colonies grow in the (Ia)-containing medium. Optionally (A) that grow in the supplemented medium may be plated on a field of different (I) to identify them from their specific (I)-utilising characteristics. The cells are yeasts or prokaryotes, particularly Gram-negative bacteria and specifically E. coli. They express an exogenous (II) and utilise e.g. maltose, ribose or rhamnose. (B) is genetically marked by making (a) a non-reversing, non-suppressing alteration in its genotype, in which case the sample is not diluted before plating or (b) a genotypic alteration that results in a carbohydrate utilisation revertant or suppressant, in which case the sample is serially diluted before plating. Optionally the strain is doubly marked by altering two (I)-utilisation pathways; (i) one type (a), in ribose utilisation and the other a reverting or suppressing mutation in rhamnose utilisation or (ii) both type (a), in maltose and ribose utilisation. Where two alterations are present, two plates are used in step (b), each supplemented with different (I). The vessel is a fermentor containing, before dilution, 108-1011 colony-forming units (cfu)/ml.
Patent IL-184870-A0 (IL)
Title: Method for producing a dental prosthesis and a device for carrying out said method
Filed: 2007-07-26
Abstract: The method involves placing real guiding cylinders in drilled holes so as to form a surgical guide, and drilling a jaw model through the surgical guide using the guiding cylinders. An implant is inserted into analogue drilled holes in a preset position of processed images and marking a rotatable position. A dental prosthesis is formed according to the model prior to arranging it in patient`s mouth. An independent claim is also included for an equipment for implanting a dental prosthesis in a jaw of a patient.
Patent IL-200749-A0 (IL)
Title: Modified fgf-21 polypeptides and their uses
Filed: 2009-09-06
Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
Patent IL-201178-A0 (IL)
Title: Conception cap and related methods
Filed: 2009-09-24
Abstract: A conception cap includes a dome having a collapsible sidewall, an annular rim, and three or more, gripping flanges along the inner surface of the rim. The gripping flanges may effectively position and secure the cap over the cervix for the concentration of semen on the cervical os to effect fertilization independently or with the aid of biologically active agents. The cap may additionally include a handle extending from the annular rim at an angle.
Patent RO-135887-A0 (RO)
Title: Double-flow turbo engine with very high by-pass ratio
Inventor: SANDU CONSTANTIN
IPC: F02K3/04
Filed: 2022-03-21
Abstract: The invention relates to a double-flow turbo engine, meant to equip a passenger aircraft. According to the invention, the turbo engine consists of circular sectors (1), with aerodynamic cross-section fixed onto some fan blades (2) by means of trapezoidal channels (3) which are arranged in some trapezoidal legs (4) from the tip of the fan blades (2), which are fixed in the central hub by means of other trapezoidal legs (5), the circular sectors (1) consisting of an outer shell (6) and some internal supports (7), which connect the fairing to the walls of the trapezoidal channel (3), an extremely strong and light construction being achieved this way similar to the model of bird bone that has an apparent density of Rho = 0.3 kg/m3.
Patent MA-23213-A1 (MA)
Inventor: ROBERT YA-LIN PAN
IPC: C11D3/12
Filed: 1994-06-01
Abstract: Granular detergent compositions comprise conventional ingredients and a perfume delivery system which comprises Type X or Type Y Zeolites having a perfume releasably adsorbed within their pores, and a barrier matrix comprising a fluid polyol or diol which is insoluble with the perfume and a solid polyol containing more than three hydroxyl moieties. Methods of depositing said perfume onto fabric surfaces are disclosed.
Patent MA-25147-A1 (MA)
Title: Cable colore et procede de fabrication
Inventor: CHENG-LANG TSAI
Filed: 2000-07-12
Abstract: L'INVENTION CONCERNE UN CâBLE COLORÉ COMPRENANT AU MOINS UN CORPS CONDUCTEUR,  AU MOINS UN ENROULEMENT COLORÉ BOBINÉ UNIFORMÉMENT AUTOUR DU CORPS CONDUCTEUR ET FIXÉ à CELUI-CI,  ET UN REVeTEMENT DE MATIèRE PLASTIQUE TRANSPARENTE FORMÉ SUR L'ENROULEMENT COLORÉ PAR MOULAGE PAR INJECTION.  CHAQUE CORPS CONDUCTEUR EST ESPACÉ DE L'AUTRE POUR ASSURER UN ISOLEMENT ENTRE EUX,  TRANSMETTRE DES SIGNAUX ET/OU PERMETTRE à DU COURANT DE PASSER.
Patent MA-40308-A1 (MA)
Title: Pyridine-2- amides utiles comme agonistes de cb2
Inventor: BENDELS STEFANIE
IPC: C07D213/81
Filed: 2013-12-04
Abstract: La présente invention concerne des agonistes de cb2 de formule (i) où r1 à r4 sont tels que définis dans la description et les revendications. Le composé de formule (i) peut être utilisé comme médicament.