baber/WOPTO huggingface dataset:
Patent PT-910563-E (PT)
Inventor: MILLER WILLIAM H
IPC: A61K31/415
Filed: 1996-06-28
Abstract: Multicyclic derivs. of formula (I) and their salts are new: A1 = C or N; E = 5-6 membered heteroaromatic or 6 membered aromatic ring opt. substd. by R3 or R4; X1-X2 = CHR1CH, CR1=CH, NR1CH, SOuCH or OCH; X3 = CR5R5', NR5, SOu or O; R' = H, 1-6C alkyl, 3-7C cycloalkyl-0-4C alkyl or Ar-0-4C alkyl; R" = R', COR' or CO2R5; R"' = 1-6C alkyl, 3-7C cycloalkyl-0-4C alkyl or Ar-0-4C alkyl; R1 = H, 1-6C alkyl, 3-7C cycloalkyl-0-4C alkyl or Ar-0-4C alkyl; R2 = OR', NR'R", NR'SO2R"', NR' OR', OCR'2CO2R', OCR'2OCOR', OCR'2CONR'2, CF3 or COCR'2R2'; R2' = OR', CN, SOrR', SO2NR'2, COR'CONR'2 or CO2R'; R5, R5' = H, 1-6C alkyl, 3-7C cycloalkyl-0-4C alkyl or Ar-0-4C alkyl; R6 = W(CR'2)q Z(CR'R10)r U(CR'2)5 V or W'(CR'2)qU(CR'2)s; R3, R4, R7 = H, halo, OR12, SR12, CN, NR'R12, NO2, CF3, CF3SOr, CO2R', CONR'2, R14-0-6C alkyl, R14-1-6C oxoalkyl, R14 2-6C alkenyl, R14-2-6C alkynyl, R14-0-6C alkoxy, R14-0-6C alkylamino or R14-0-6C alkyl-SOr; R8 = R', COR', CN, NO2, SO2R' or CO2R5; R9 = R', CF3, SR' or OR'; R10 = H, 1-4C alkyl or NR'R"; R12 = R', COR', CONR'2, CO2R5, SOmR' or SO2NR'2; R14 = H, 3-6C cycloalkyl, Het or Ar; R15 = H, 1-10C alkyl, 3-7C cycloalkyl-0-8 C alkyl or Ar-0-8C alkyl; U, V = absent or CO, CR'2, C(= CR15 2) (sic), SOn, O, NR15, CR15' OR15, CR'(OR")CR'2, CR'2CR'(OR"), COR'2, CR15 2 CO, CONR15, NR15CO, OC(O), CO2, C(S)O, OC(S), C(S)NR15, NR15C(S), SO2NR15, NR15SO2, N=N, NR15NR15, NR15C(R15)2, NR15C(R15)2, C(R15)2O, OC(R15)2, C?=C, CR15 = CR15, Het or Ar; provided that U and V are not both absent; W = R'R"N, R'R"NR'N, R'R"NR'NCO, (R')2NR'NC(=NR'), R'ONR'C(=NR')-, (R'2N)C(R9)=N-, (R'2N)2C=N-, R9C(=NR")NR', R"R'NC(=NR')Y, R"R'NC(=NR')NR'X-, R"R'NC(=NR8)NR' or a nitrogen contg. ring; W' = a gp. of e.g. formula (a) and (b); Q = NR', O or S; Ra = H, 1-6C alkyl, Ar-0-6C alkyl, Het-0-6C alkyl, 3-6C cycloalkyl 0-6C alkyl, halo, OR1, SR1, COR1, OH, NO2, N(R1)2, CO(NR1)2 or CH2N(R1)2; Rb, Rc = H, 1-6C alkyl, Ar-0-6C alkyl, Het-0-6C alkyl, 3-6C cycloalkyl-0-6C alkyl, halo, OR1, SR1, COR1, OH, NO2, N(R1)2, CO(NR1)2 or CH2N(R1)2; or Rb+Rc = 5-6 membered opt. aromatic ring opt. substd. by halo, 1-4C alkyl, OR1, SR1, COR1, OH, NO2, N(R1)2, CO(NR1)2, CH2N(R1)2, CN or R"R'NC(=NR'); X = NCR', CO or O; Y = absent, S or O; Z = (CH2)t, Het, Ar or 3-7C cycloalkyl; m = 1-2; q, n = 0-3; r-u = 0-2; v, w = 0-1; Ar = ph or naphthyl opt. substd. by 1-3 R7; R7 = 1-4C alkyl, 1-4C alkoxy, 1-4C alkylthio, trifluoroalkyl, OH, Cl, F, Br or I; Het = 5-6 membered monocycle or 9-10 membered bicycle contg. 1-3 N, O or S. opt. substd. by 1-3 R7.
Patent PT-784902-E (PT)
Inventor: HARRISON ROBERT G
IPC: H04N5/445
Filed: 1996-07-18
Abstract: Systems (34) which have an integrated unit that allows both television signals and information retrieved from an onboard information storage device (32) to be presented in a visual, audio or video/audio learn-while-doing form via output devices such as television screens and audio speakers. The operating mode - television or stored information retrieval and display - is selected by the user. The user is coached through steps leading to retrieval and presentation of the wanted information if the information retrieval mode is selected. To this end, the data storage devices are encoded with data corresponding to: (a) information for coaching a user in accomplishing one or more steps of a specified task in learn-then-perform way, and (b) an instruction set which enables the user access to access the information on a user-selected step of the task. Methods for providing the encoded data storage devices and for employing those devices in the operation of the systems are also described. A novel remote control (36) allows the system user to choose the mode of operation and to navigate the steps needed to reach the wanted information from a location convenient to the user.
Patent PT-977505-E (PT)
Inventor: THARALSON DOUGLAS E
IPC: A47D7/04
Filed: 1997-08-29
Abstract: A first playpen enclosure that converts easily to a bassinet, a changing table or a bed-side crib (hereinafter referred to as a "co-sleeper") that attaches securely to the parents' bed. A described second enclosure support system maintains a padded enclosure and rigid floor panel at a predetermined level below the top of the playpen to form the bassinet. The second enclosure has a back, two sides, a bottom and a front flap that overhangs the front horizontal rail. The upper front corners are segmented into a removable section and a fixed section to facilitate the removal and unseating of the front horizontal rail to a second position at a first predetermined distance from the top position. Cooperating junctures affixed to the front vertical rails accept the removable sections and securely seat the rail in this second position. The supports, padded enclosure and rigid floor panel complete the changing table with the front flap hanging down in front. The playpen can be placed adjacent the parents' bed with the front flap extended over the bed for use as a co-sleeper. For such use, uniquely designed reinforcing straps secure the unit to the parents' bed and prevent the co-sleeper from sliding, buckling or lifting. The unit is easily folded with the components into a compact package carrying case for transport or storage.
Patent PT-944612-E (PT)
Inventor: KITAMURA SATOSHI
IPC: C07D295/32
Filed: 1997-12-05
Abstract: PCT No. PCT/JP97/04451 Sec. 371 Date Jun. 14, 1999 Sec. 102(e) Date Jun. 14, 1999 PCT Filed Dec. 5, 1997 PCT Pub. No. WO98/25914 PCT Pub. Date Jun. 18, 1998Hydrates of N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide, which are stable against heat, light, and humidity, are described. The material is easy to handle under ordinary interior humidity conditions. N-(4-acetyl-1-piperazinyl)-4-fluorobenzamide hydrate is useful as a medicament in the treatment of amnesia and senile dementia.
Patent PT-872503-E (PT)
Inventor: DIRSCHL FRANZ
IPC: C08G18/80
Filed: 1998-03-14
Abstract: A composition (CX), obtained by (a) reacting di- isocyanate(s) (component I) with 2-8C alcohol(s) and/or mono- and/or di-ethers thereof with at least two alcoholic hydroxyl groups and not more than two C-O-C linkages (component II) to give a product which still contains free isocyanate groups, (b) reacting with amine(s) containing two or more alcoholic OH groups to give another product which still contains free NCO groups (with the condition that at least one of the alcohols, ethers and amines used in (a) and (b) contains 3 or more alcoholic OH groups), (c) blocking the free NCO groups with a blocking agent and (d) possibly dispersing the product in water and adjusting the pH.
Patent PT-878672-E (PT)
Inventor: ANDRE AMPHOUX
IPC: F24F7/003
Filed: 1998-05-12
Abstract: The system consists of a main vertical duct (4) with its upper end (4a) closed, its lower end (4b) connected to a source of air (5), and one or more lateral outlets (6). It also has at least one supplementary air injector (7) to increase the flow, situated towards the lower end of the duct. The system also incorporates an air extractor unit with a main vertical duct (41) which has its upper end (41a) situated above the building, and one or more extractor intakes (43) along its length. The extractor unit has an additional air injector (44) which is identical to the one used on the intake but is situated at the outlet end of the duct to increase the flow of air through it.
Patent PT-992025-E (PT)
Inventor: RITTER RUDOLF
IPC: G06Q20/00
Filed: 1998-03-05
Abstract: A transaction method between a client and a terminal (2) connected to a telecommunication network comprises the transmission of at least one client identification (IDUI), a terminal identification (POSID), and transaction-specific data to a financial server connected to the telecommunication network. The terminal identification is read or entered in the terminal and transmitted by the telecommunication network to the financial server. The client is equipped with a SIM card which can be connected functionally to a mobile apparatus. The client identification transmitted to the financial server is read in the memory of the SIM card and transmitted to the financial server via at least one interface.
Patent PT-994705-E (PT)
Inventor: HORROBIN DAVID FREDERICK
IPC: A23L33/00
Filed: 1998-07-22
Abstract: Compositions of GLA and/or other EFAs with TA or related compounds, and their use in therapy or nutrition or in preparation of compositions for therapy or nutrition, especially to improve cell membrane EFA concentration and impaired nerve function and blood flow.
Patent PT-1037604-E (PT)
Inventor: COTTAGE PRITCHARD YVONNE MARY
IPC: A61K47/08
Filed: 1998-11-20
Abstract: A medicinal aerosol formulation comprising propellant particles of a first drug suspended in propellant and a second drug completely dissolved in the aerosol formulation. The first drug is salbutanol, terbutaline or perbuterol and the second drug is beclamethasone or budesonide. The propellant is a hydrofluoroalkane (HFA).
Patent SG-30606-G (SG)
Title: Process for stereospecific alpha-olefin polymerization and catalytic system to be used in this process
Inventor: FIASSE PAUL
IPC: C08F4/649
Filed: 1988-04-12
Abstract: The catalyst system comprises:  (a) a solid based on complexed titanium trichloride, (b) an organometallic compound of metals of groups IA, IIA, IIB and IIIB of the Periodic Table, and in addition  (c) an organic silicon oxygen compound. The process carried out in the presence of this catalyst system enables propylene to be polymerised with an improved catalyst activity.
Patent IE-830134-L (IE)
Title: Cyclohexane diones
IPC: A01N35/06
Filed: 1983-01-24
Abstract: The invention concerns novel compounds of the formula I <IMAGE> I wherein Z is selected from hydrogen, halogen, C1 to C6 alkyl, and C1 to C6 alkoxy; Y is selected from halogen, C1 to C6 alkyl and C1 to C6 alkoxy; X is selected from halogen, C1 to C6 alkyl and C1 to C6 alkoxy and if Y is methyl and Z is hydrogen or methyl then at least one of X is not methyl; R1 is selected from hydrogen, alkyl, alkenyl, alkynyl, substituted alkyl, alkylsulfonyl, arylsulfonyl, acyl and an inorganic or organic cation; R2 is selected from alkyl, substituted alkyl, alkenyl, haloalkenyl, alkynyl and haloalkynyl; R3 is selected from alkyl, fluoroalkyl, alkenyl, alkynyl and phenyl; and m is an integer chosen from 1 to 3. The compounds are cereal selective herbicides and in further embodiments the invention provides processes for the preparation of compounds of formula I, intermediates useful in the preparation of compounds of formula I, herbicidal compositions containing as active ingredient a compound of formula I, and processes for severely damaging or killing unwanted plants by applying to the plants or to the growth medium of the plants an effective amount of a compound of formula I.
[US4806141A]
Patent IE-810176-L (IE)
Title: Crystalline salts.
IPC: C07D/
Filed: 1981-01-30
Abstract: The invention relates to the novel crystalline hydrochloride and the crystalline hydrobromide of 7 beta -[2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid pivaloyloxymethyl ester, a process for the production thereof, and pharmaceutical preparations that contain these compounds.
Patent IE-34016-L (IE)
Title: Anilino-phenylethyl alcohols
IPC: C07C213/00
Filed: 1970-02-19
Abstract: 1304622 Ortho-anilino-phenethyl alcohols CIBA-GEIGY AG 19 Feb 1970 [20 Feb 1969] 7912/70 Heading C2C Novel compounds of the Formula I wherein R 1 , R 2 and R 3 are independently hydrogen, chlorine, fluorine, bromine, methyl or ethyl and R 1 may additionally be trifluoromethyl and R 4 is hydrogen, chlorine, fluorine, bromine, methyl or methoxy may be prepared by reducing the corresponding o-anilino-phenyl acetic acid or an ester thereof or hydrolysing the corresponding N-acylated compound. The corresponding o-anilino-phenyl acetric acid may be formed by reductive ring opening of an N-phenyl substituted indole-2,3-dione or hydrolytic ring opening of an N-phenylsubstituted-2-indolinone, in which, when present, a substituent corresponding to the R 4 position in I is converted from hydroxy to methoxy. N - Phenyl - 2,61 - dichloroaceto - o - toluidide may be prepared by acetylation of 6-chloro-otoluidine to yield 6<SP>1</SP> - chloroaceto - o - toluidine followed by treatment with bromobenzene in the presence of copper and base to yield 6-chloro-N- phenyl-aceto-o-toluidide which is reacted with chloroacetyl chloride to yield the required compound. Similarly 2 - chloro - N - (2,6 - dichlorophenyl).aceto-p-anisidide may be prepared by reaction of 2<SP>1</SP>,6<SP>1</SP>-dichloroacetanilide with pbromoanisole in the presence of copper and base to yield .N-(2,6-dichlorophenyl)-p-anisidine which is reacted with chloroacetyl chloride to yield the required compound. The intermediate indole-2,3-dione 1-(2,6- xylyl) - indole - 2,3 - dione may be prepared by reaction of o-chlorobenzoic acid with 2,6- xylidine in the presence of base to yield N- (2,6-xylyl)-anthranilic acid which is decarboxylate to yield N-phenyl-2,6-xylidine which with oxalyl chloride yields N.phenyl-2<SP>1</SP>, 6<SP>1</SP>-dimethyl'- oxaniloyl chloride which may be cyclized in the presence of aluminium chloride to the required compound. Pharmaceutical compositions of compounds I show antiphlogistic, analgesic and antipyretic activity when administered orally, parenterally, rectally or topically with the usual excipients.
[GB1304622A]
Patent IE-44888-L (IE)
Title: 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and¹processes for the preparation thereof
IPC: A61P31/04
Filed: 1977-03-01
Abstract: Antibiotic cephalosporin compounds, method of making and pharmaceutical composition thereof represented by the general formula wherein R1 is amino, lower alkylamino, a protected amino, a protected lower alkylamino, hydroxy or lower alkoxy, R2 is hydrogen, acyloxy, pyridium or a heterocyclicthio group which may have suitable substituent(s), R3 is carboxy or its derivative, A is carbonyl, hydroxy(lower)alkylene or a protected hydroxy(lower)alkylene and R4 is hydrogen or halogen, or R2 and R3 are linked together to represent a group of the formula -COO-, this divisional application being directed to intermediate compounds of the formula:
Patent IE-35186-L (IE)
Title: Amines
IPC: A61K31/135
Filed: 1971-05-03
Abstract: 1334430 Aralkylamines and derivatives F HOFFMANN-LA ROCHE & CO AG 5 May 1971 [6 May 1970] 13220/71 Heading C2C Novel compounds of formula wherein one of the symbols R 1 and R 2 represents a formyl group and the other symbol represents a hydroxy group (the symbols R 1 and R 2 being in the ortho- or para-position to each other), the symbols R 3 and R 4 each represents a hydrogen atom or a lower alkyl group, the symbol R 5 represents a hydrogen atom or a carboxyl or lower alkoxycarbonyl group and the symbol R 6 represents a hydrogen atom or a lower alkanoyl or aroyl group, their optical antipodes and pharmaceutically acceptable salts thereof are prepared by formylation of a compound of formula wherein one of the symbols R 7 and R 8 represents a hydrogen atom and the other symbol represents a hydroxy group or a lower alkoxy group (the symbols R 7 and R 8 being in the ortho- or para-position to each other), or an optical antipode or a salt thereof and converting any lower alkoxy group denoted by R 7 or R 8 in the formylation product into a hydroxy group and, if desired and in any desired sequence, converting a compound of Formula I obtained in which the symbol R 5 represents a lower alkoxycarbonyl group into a compound of Formula I in which the symbol R 5 represents a carboxyl group, esterifying a compound of Formula I in which the symbol R 5 represents a carboxyl group, converting a compound of Formula I in which the symbol R 6 represents a lower alkanoyl or aroyl group into a compound of Formula I in which the symbol R 6 represents a hydrogen atom if desired, optionally with salt formation and/or resolution. Pharmaceutical compositions in conventional forms for enteral or parenteral administration and having hypotensive and appetite inhibiting action comprise an above novel compound or salt and a carrier therefor.
[GB1334430A]
Patent IE-39696-L (IE)
Title: Bulk polymerisation of vinyl chloride
IPC: C08F14/00
Filed: 1974-04-02
Abstract: A process for preparing polymers and copolymers containing vinyl chloride by bulk polymerization which includes feeding to a reaction zone of a vessel maintained at polymerization temperature (t1) a solution (A) comprising monomeric material to be polymerized and at least one polymerization initiator, solution (A) being prepared continuously immediately before being fed to the reaction zone by mixing a constituent (B) comprising at least 50% of the monomeric material at a temperature (t2) which is within 10 DEG C of t1, and a solution (C) of the initiator of initiators in an organic solvent which would include the remainder, if any, of the monomeric material, and in which, when the polymerization reaction is carried out in a two stage polymerization including a first pre-polymerization and a subsequent polymerization, the pre-polymerization reaction is carried out under a high stage of agitation while the polymerization step is carried out at a lower stage of agitation.
[US3933776A]
Patent IE-39753-L (IE)
Title: Making bags from tubular webs
IPC: B31B29/00
Filed: 1974-04-30
Abstract: 1470653 Making bottom folded bags; seaming NATIONAL PETRO-CHEMICAL CORP 6 June 1974 [1 May 1973] 20676/73 Headings B5D and B5K In an apparatus for forming bottom folded bags, Fig. 14, lower and upper grippers 56 and 114 which grip a side gussetted bag section at lower and upper side edges GEL and GEU adjacent a sealed end S, are movable at different speeds in the longitudinal direction of the bag section to fold the bottom. The lower grippers are moved faster than the upper grippers when the sealed end S is the leading end, and the upper grippers are the faster when the sealed end S trails. In the embodiment shown the slower moving upper grippers 114 are inclined upwardly in the direction of feed of the bag sections, and bars (160) Fig. 15 (not shown) which are carried with the lower grippers, can lie in the top walls of the bag sections to define edges about which the top walls are folded during the bottom folding. The lower grippers may also carry a spacer (162) Fig. 15 (not shown) to open the gussets. In operation of the apparatus, guides 61 open the gussets in a web which has been subjected to flame treatment and printed on, and guide the lower grippers 56 which are carried by chains 54, into engagement with the lower edges GEL of the web. Heated sealing bars 62 and back-up bars (68) Fig. 1 (not shown) which are mounted between respective conveyor chains 64 and (70) Fig. 1 (not shown) for movement with the web, then transversely heat seal the web at spaced intervals. Adjustable pressing bars (76) Fig. 8 (not shown) are provided behind at least the heated sealing bars 62. The bag sections are severed from the sealed web by a rotary cutter and opened by a blast of ionized air from a nozzle 98 to facilitate the gripping of the upper edges GEU by the grippers 114. After the bottom folding, brushes 144 deaerate the bags prior to the bags being pressed by pressing belts (148, 157) Fig. 2 (not shown). The finished bags are stacked and the resulting bundle wrapped.
[GB1470653A]
Patent IE-38151-L (IE)
Title: Controlled residence time medicaments
IPC: A61K9/32
Filed: 1973-06-07
Abstract: 1428426 Sustained release compositions; diagnostic devices PURDUE RESEARCH FOUNDATION 5 June 1973 [9 June 1972] 26662/73 Heading A5B A sustained release medicament formulation with prolonged gastric residence comprises (a) a medicament core and (b) a pharmaceutically acceptable coating on the core comprising a crosslinked polymeric film which comprises a prepolymer crosslinked with a cross-linking agent at a ratio of 8 parts by weight of prepolymer to 0.15 to 4 parts by weight of crosslinking agent, the prepolymer being a copolymer of (i) 20-90 parts by weight of a substituted or unsubstituted unsaturated dicarboxylic acid or acid anhydride having 1 to 3 carbon atoms between the two carboxylic groups, and (ii) 10-80 parts by weight of an alkene of 2 to 6 carbon atoms, styrene or an alkyl vinyl ether in which the alkyl radical contains 1 to 16 carbon atoms, the polymeric film being waterhydratable, water-permeable and swellable in the presence of gastric fluids. A large number of active ingredients are specified as being suitable for use in the medicament core. The core may also be coated with a binary polymeric film including a pharmaceutically acceptable, substantially water-insoluble polymeric component and a pharmaceutically acceptable polymeric component as defined in (b) above. The medicament core may be replaced by a diagnostic device such as a Heidelberg capsule.
[GB1428426A]
Patent FI-814110-L (FI)
Inventor: HOLTON JAMES ARTHUR
IPC: B23D15/08
Filed: 1981-12-21
Abstract: A cutting or shaping mechanism is described in which the cutting or pressing force is applied to a moving blade or shaping assembly (20, 83,102,203) over a limited part of the length of that assembly, including where the assembly is in engagement with the work. The application of the cutting or pressing force is moved progressively along the assembly to cause the assembly to roll on the work and progressively cut or apply pressure to the work. The invention is particularly applicable to a rolling cut shear having a single moving blade assembly (20) or a pair of oppositely curved moving blade assemblies (97, 102).
Patent FI-850711-L (FI)
Inventor: LINDAHL JONAS ARNE INGVAR
IPC: D21D5/02
Filed: 1985-02-21
Abstract: Improved chemimechanical, particularly chemithermomechanical pulp, (CTMP) is produced by defibrating or refining chips, screening and dividing the screened pulp into fractions of mutually different fiber composition. The defibrated or refined pulp is divided in a first screening means by taking-out at least 30% by weight of the incoming fiber suspension as a first long-fiber fraction and a first fine-fiber fraction, this latter being divided in a second screening means into a second long-fiber fraction which is combined with the first long-fiber fraction to form a long-fiber fraction of improved properties, which is removed from the process, and a second fine-fiber fraction of improved properties, which is also removed from the process.
Patent FI-853907-L (FI)
Inventor: COOPER GARY F
IPC: C07C49/255
Filed: 1985-10-08
Abstract: The compound of the Formula I <CHEM>  wherein  R<1> and R<2> are hydrogen or an ether forming group; and X is hydrogen, halo, trifluoromethyl, lower alkyl or lower alkoxy. These compounds are useful intermediates for aking PGE and PGF derivatives having an allenic function.
Patent IE-781054-L (IE)
Title: Purification of nucleotide sequence suitable for expression¹in bacteria
IPC: C07K14/575
Filed: 1978-05-26
Abstract: Recombinant DNA transfer vectors containing codons for human somatomammotropin and for human growth hormone.
[US4363877A]
Patent IE-811073-L (IE)
Title: Heparin esters
IPC: C08B37/10
Filed: 1981-05-13
Abstract: Esters of heparin, which are derived from heparin by replacement of the carboxyl groups of heparin by groups of the formula: <IMAGE> (I) in which R is a hydrogen atom or a methyl group and A is a hydrogen atom or a methyl, phenyl, <IMAGE> X representing a chlorine atom or a nitro, alkyl containing 1 to 4 carbon atoms or methoxy group and Y representing a hydrogen or chlorine atom, the replacement being a partial or total replacement when A is other than a hydrogen atom or a methyl or phenyl group and the replacement being a partial replacement corresponding to a 10% to 90% esterification percentage of the carboxyl groups when A is a hydrogen atom or a methyl or phenyl group, and the alkali metal, alkaline earth metal, magnesium, quaternary ammonium and amine salts of the said esters. These compounds are intermediate products for preparing medicaments.
[US4440926A]