baber/WOPTO huggingface dataset:
Patent CA-2552892-A1 (CA)
Inventor: CLAUSEN HENRIK
IPC: A61K38/14
Filed: 2005-01-10
Abstract: The present invention provides polypeptides that include an O-linked glycosylation site that is not present in the wild-type peptide. The polypeptides of the invention include glycoconjugates in which a species suc h as a water-soluble polymer, a therapeutic agent of a biomolecule is covalent ly linked through an intact O-linked glycosyl residue to the polypeptide. Also provided are methods of making the peptides of the invention and methods, pharmaceutical compositions containing the peptides and methods of treating, ameliorating or preventing diseased in mammals by administering an amount of a peptide of the invention sufficient to achieve the desired response.
Patent CA-2553608-A1 (CA)
Title: Process for the production of asymmetric transformation catalysts
Inventor: CHEN WEI-PING
IPC: B01J31/00
Filed: 2005-01-14
Abstract: The present invention relates to process for the production of chiral ligands comprising providing a starting material of Formula (A): wherein X* is a chiral or achiral directing group; and (i) is an optionally substituted mono-or polycyclic aryl or cycloalkyl group; ortholithiating the substrate;  converting the ortho-lithiated substrate to a phosphine group having the formula -PR1 R1", R1 being selected from substituted and unsubstituted, branched- and straight-chain alkyl, substituted and unsubstituted cycloalkyl, substituted and unsubstituted carbocyclic aryl, and substituted and unsubstituted heteroaryl wherein the or each heteroatom is independently selected from sulphur, nitrogen, and oxygen, R1" being different from R1 and being selected from substituted and unsubstituted, branched- and straight-chain alkyl, substituted and unsubstituted cycloalkyl, substituted and unsubstituted carbocyclic aryl, and substituted and unsubstituted heteroaryl wherein the or each heteroatom is independently selected from sulphur, nitrogen, and oxygen; and optionally or if necessary converting X* to a different grouping to produce a chiral ligand.
Patent CA-2553714-A1 (CA)
Inventor: SUEMATSU MAKOTO
IPC: A61K47/12
Filed: 2005-01-24
Abstract: It is intended to provide a support which accumulates in an injured tissue and acts as an agent regulating the platelet function; a drug delivery method using the support; and a medicinal composition containing the support. It is also intended to provide a support having a non-cationic surface; a drug carrier comprising this support; and a medicinal composition.
Patent CA-2554829-A1 (CA)
Inventor: HUANG WEI YAO
IPC: G11C11/34
Filed: 2005-02-03
Abstract: A device employs a method for determining the data bus width of a non-volatile memory, such as NAND flash memory. The method performs at least two read operations on the non-volatile memory so as to test the changing of selected data bits. The method may be performed such that weak pull down and pull up operations are performed to test the data outputs of the non-volatile memory.
Patent CA-2554975-A1 (CA)
Title: Methods of preventing and treating sars using low ph respiratory tract compositions
Inventor: MULLET BENOIT MAURICE
IPC: A61K33/24
Filed: 2005-02-01
Abstract: The present invention is directed to methods of preventing and treating Severe Acute Respiratory Syndrome (SARS) by the administration of respiratory tract compositions having low pH values. The respiratory tract compositions have a pH of from about 3.0 to about 5.5, and are preferably administered to areas of the respiratory tract such as the nasal cavity to effectively prevent and treat respiratory tract viral infections, particularly SARS. The respiratory tract compositions comprise an organic acid in combination with a metal compound.
Patent CA-2558152-A1 (CA)
Inventor: ROCHE CHRISTINA E
IPC: A01H5/00
Filed: 2005-02-26
Abstract: The invention relates to transgenic expression constructs and vectors comprising plant promoters with a non-seed tissue, preferably vegetative plant tissue specific expression profile, and the use of these transgenic expression constructs or vectors for the transgenic expression of nucleic acid sequences in plants. More preferably, the promoters of the invention are the the promoter of the Pisum sativum ptxA gene, or the promoter of the Glycine max extensin (SbHRGP3) gene, and functional equivalent fragments and functional equivalent homologs thereof, or their complements, having essentially the same promoter activity. The invention furthermore relates to transgenic plants and plant cells transformed with these expression constructs or vectors, to cultures, parts or propagation material derived therefrom, and to the use of same for the preparation of foodstuffs, animal feeds, seed, pharmaceuticals or fine chemicals, to improve plant biomass, yield, or provide desirable phenotypes.
Patent CA-2559821-A1 (CA)
Title: Method for producing an aromatic polycarbonate
Inventor: HACHIYA HIROSHI
IPC: C08G64/30
Filed: 2005-06-14
Abstract: A process for producing an aromatic polycarbonate of high quality which comprises melt-polymerizing an aromatic dihydroxy compound with a diaryl carbonate, characterized in that the step of mixing the aromatic dihydroxy compound with the diaryl carbonate comprises dissolving the aromatic dihydroxy compound which is solid and/or liquid and a catalyst in the diaryl carbonate in a molten state in the presence of an inert gas.
Patent CA-2566893-A1 (CA)
Inventor: PAAVOLA JYRI
IPC: G01B/
Filed: 2005-04-12
Abstract: The invention relates to a device for optical inspection of the open surfaces (19 of objects from at least two different viewing directions (P1, P2). The device comprises a telecentric imaging unit (11 or 12, an angle mirror (13) and auxiliary mirrors (8) within the area (K) of the telecentric imaging unit, between this and the object. The object is placed between the arms (3a, 3b) of the angle mirror (13) and the telecentric imaging unit is directed towards the combination of object and angle mirror. Said auxiliary mirrors (8) have been oriented and positioned at intervals from the telecentric imaging unit such that the differences of distance of the viewing directions (P1 and/or P2 and/or P3 and/or P4) via the two arms (3a and 3b) of the angle mirror or via one arm (3a tai 3b) or not via the arms are compensated as they pass via said auxiliary mirrors.
Patent CA-2568312-A1 (CA)
Inventor: HA YONG GAN
IPC: B02C13/14
Filed: 2005-05-23
Abstract: A vertical shaft impact crusher is provided to maximize the lifetime of a rotor while to effectively crush the target objects. The vertical shaft impact crusher, comprising a rotating body positioned at a rotating shaft and to which target objects are introduced from upwards, wherein a protective layer is formed inside the rotating body such that the introduced target objects are gradually enlarged in diameter along an upward direction of the rotating body by the rotating movement of the rotating body, thereby forming an inner surface thereof with a sectional shape of funnel. Further, another vertical shaft impact crusher is provided, comprising an upper rotating body positioned on a rotating shaft, and a lower rotating body positioned below the upper rotating body, wherein a lower protective layer is formed inside the lower rotating body such that the target objects introduced from the upside are gradually enlarged in diameter along an upward direction of the lower rotating body by the rotating movement of the lower rotating body, thereby forming an inner surface thereof with a sectional shape of funnel, wherein an upper protective layer is formed such that the target objects escaped from the lower protective layer are moved along an inside height of the upper rotating body, wherein the diameter of the upper protective layer is larger than the lower protective layer, and wherein the upper protective layer is formed in an inverse funnel shape relative to that of the lower protective layer.
Patent CA-2569393-A1 (CA)
Inventor: HARRISON JEFFREY
IPC: A01K61/80
Filed: 2005-05-31
Abstract: The present invention provides for an apparatus for dispensing a slurry feed suitable for fish under the surface of an aqueous body, the apparatus comprising a housing having a feed inlet and radial feed dispensing means, means for providing a slurry containing a feed product to the feed inlet means in the housing and a radial feed dispensing means comprising a plurality of spaced-apart slurry dispensing outlets therein for dispensing slurry radially and outwardly from the housing under the water surface.
Patent CA-2569758-A1 (CA)
Title: Extraction of alkaloids from opium
Inventor: TOMAZI KEITH G
IPC: C07D221/00
Filed: 2005-05-06
Abstract: A method for extracting at least one alkaloid from opium that includes dissolving opium in a solvent, heating the dissolved opium solution, cooling the dissolved opium solution, adjusting the pH of the dissolved opium solution with at least one first weak acid, filtering the dissolved opium solution to recover a filtrate; and then separating and purifying at least one alkaloid in the filtrate. Preferably, this includes an additional step of chilling the opium solution after adjusting the pH of the dissolved opium solution with at least one first acid. The preferred method for separating and purifying at least one alkaloid in the filtrate includes utilizing preparative liquid chromatography, however, solvent extraction and filtration can also be utilized.
Patent CA-2570299-A1 (CA)
Title: Method and apparatus for carrying out a metallurgical process
Inventor: REIFFEL LEONARD
IPC: C21B5/00
Filed: 2005-06-12
Abstract: A metallurgical process involves providing an ingredient enclosure and placing a plurality of granules of a first material in the ingredient enclosure. The first material contains a first ingredient in a metallurgical process. A  metallurgical process furnace having a chamber in which ingredients for the metallurgical process are added is provided and the ingredient enclosure and the first material are added to the chamber. The chamber is heated after the addition of the ingredient enclosure and the first material to the chamber, although it may also be heated prior to such addition. In one form, the granules comprise mill scale and the metallurgical process furnace is a blast furnace.
Patent CA-2571276-A1 (CA)
Inventor: ALIGHIERI TIZIANO
IPC: A61K47/02
Filed: 2006-12-15
Abstract: Modified release formulation of lithium carbonate in microgranules or similar comprising, for around 300 Kg of Lithium Carbonate, at least: - Overall Povidone in quantity between 8.0 Kg and 40.0 Kg;  - Ethylcellulose in quantity between Kg 0. 9 and Kg 3.6.
Patent CA-2571684-A1 (CA)
Inventor: GASPER THOMAS P
IPC: A01M1/20
Filed: 2005-06-29
Abstract: A volatilizer has a case (101, 238) that deforms to interrupt electrical current flow through an internal heating element (208). Such a thermal custoff device is used to prevent overheating.
Patent CA-2571808-A1 (CA)
Inventor: SLAPAK MATHIAS JOZEF PAUL
IPC: B01J23/68
Filed: 2006-12-20
Abstract: The present invention relates to an improved epoxidation process and an improved epoxidation reactor. The present invention makes use of a reactor which comprises a plurality of microchannels. Such process microchannels may be adapted such that the epoxidation and optionally other processes can take place in the microchannels and that they are in a heat exchange relation with channels adapted to contain a heat exchange fluid. A reactor comprising such process microchannels is referred to as a "microchannel reactor". The invention provides a method of installing an epoxidation catalyst in a microchannel reactor. The invention also provides a process for the epoxidation of an olefin and a process for the preparation of a chemical derivable from an olefin oxide. The inverition also provides a microchannel reactor.
Patent CA-2573819-A1 (CA)
Title: Heterocyclic dye compounds for in vivo imaging and diagnosis of alzheimer's disease
Inventor: KLUNK WILLIAM E
IPC: C07D409/04
Filed: 2005-07-15
Abstract: The present invention relates to the identification of compounds that are suitable for imaging amyloid deposits in living patients. The invention relates, in part, to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease. The present invention also relates to therapeutic uses for such compounds, as examplified by compounds of the formula (I) in which Y is independently S, O, or N and m is 1, 2, or 3.
Patent CA-2576150-A1 (CA)
Inventor: RATUSHNY MICHAEL
IPC: G06F3/0482
Filed: 2005-08-04
Abstract: A convenient and intuitive software development environment for graphically grouping together groups of electrical/electronic devices and providing substantially real-time control of graphically selected groups of electrical/electronic devices and systems. In addition to substantially real-time control of a graphically selected group of electrical/electronic devices, users of the present invention can schedule commands to be executed for a group of graphically selected electrical/electronic devices, or command a group of graphically selected electrical/electronic devices to respond to a particular condition.
Patent CA-2579503-A1 (CA)
Title: Pipe clamp for a reinforcement grid, preferably in connection with floor heating installations
Inventor: JONSSON TOM
IPC: E04C5/16
Filed: 2005-09-12
Abstract: The present invention relates to a pipe clamp, in particular for the reinforcement grid in connection with the installation of floor heating, constructed as a very firm quadrangular block. The top of the pipe clamp is shaped so that it is prepared for the placing of the heat pipes in a bearing (4), arranged as two (arbitrary) on one another perpendicular cross bearings (4). The bottom of the the pipe clamp is shaped so that it is prepared for the placing on a reinforcement grid, arranged as two on one another perpendicular pipes cases (1), the depth and length of which are adapted to fit the cross mounted pipes of the reinforcement grid. The pipe clamp has a number of slits (3) in particular places centrally situated in the middle of each of the four sides of the pipe clamp and also in the very center of the pipe clamp. Hereby you achieve flexibility and avoid rigidity. The pipe clamp is placed most firmly at the cross fields of the reinforcement grid but it has an efficient clip-function and can therefore be placed steadily anywhere on the grid.
Patent CA-2580528-A1 (CA)
Title: Drug screening and molecular diagnostic test for early detection of colorectal cancer: reagents, methods and kits thereof
Inventor: LEE NANCY M
IPC: G16B40/10
Filed: 2005-09-30
Abstract: A novel approach to the early detection of colorectal cancer ("CRC"), using a molecular diagnostic test to evaluate grossly normal-appearing colonic tissue for the early detection of colorectal cancer is disclosed. Such grossly normal-appearing colonic mucosal cells may be collected from non-invasive or minimally invasive procedures. The use of novel biomarker panels for drug screening also is disclosed. Such biomaker panels may be used wholly or in part as surrogate endpoints for monitoring effectiveness of a prospective drug in the intervention of pathologies, such as cancers, for example CRC, lung, prostate, and breast, and neurodegenerative diseases, for example Alzheimer's and ALS.
Patent CA-2581016-A1 (CA)
Title: Biuret compounds for rheology control
Inventor: HAUBENNESTEL KARLHEINZ
IPC: C09D7/45
Filed: 2007-03-07
Abstract: The invention relates to biuret compounds of the idealized general formula   in which R1 is a(C1-C22) -alkylene, (C3-C22) -alkenylene, (C5-C15) -cycloalkylene, arylene, (C7-C-12) -aralkylene, a polyoxyalkylene radical or is a polyester radical, R2 is a (C1-C222) -alkyl, hydroxy- (C1-C22) -alkyl, (C3-C18) -alkenyl, aryl, (C7-C12) -aralkyl, or (C5-C12) -cycloalkyl radical, a hydroxy-, (C1-C22) -alkoxy-, (C5-C12) -cyclo-alkoxy-, or (C7-C12)-aralkoxy-polyoxyalkylene radical, or a polyester radical prepared starting from a (C1-C22) -alkanol, (C5-C12) -cycloalkanol, or (C7-C12) -aralkanol or from a (C1-C22) -alkoxy-, (C6-C12) -cyclo-alkoxy-, or (C7-C12)-aralkoxy-polyoxyalkylene, Y stands for identical or different radicals O, NH, CO-NH-NH or NH-NH-CO, R3, R4 and R5 independently of one another are a (C2-C40) -alkylene, (C3-C40) -alkenylene, (C5-C40) -cyclo-alkylene, arylene, (C7-C40) -aralkylene or polyoxy-alkylene radical or are a polyester radical, R6 is a (C1-C30) -alkyl, (C3-C-22) -alkenyl, hydroxyalkyl and hydroxyalkenyl, (C4-C13) -cycloalkyl, aryl or (C7-C12) -aralkyl radical, Z stands for one or more of the following groups COO, OCO, NHCO, CONH, NHCOO, OOCNH and NHCONH, and a is a number from 1 to 19, and also to processes for preparing them and to their use for rheology control and for thixotroping coating systems, as anti-sag agents and/or as anti-settling agents.
Patent CA-2582168-A1 (CA)
Title: External fixator element
Inventor: THOMKE ROLAND
IPC: A61B17/60
Filed: 2007-03-19
Abstract: An external fixator element, e.g. a rod, a pin or a clamping means comprises at least one contacting surface (4). At least one of the contacting surface (4) of the element responsible to establish connection between said element and a different exter-nal fixator element is provided with a rough ablated structure (4, 5, 6). The clamping can be improved if one of the elements comprise fibres (2) having parts (5) protruding over the surface (4).
Patent CA-2591321-A1 (CA)
Title: Phenylaminopyrimidine derivatives as inhibitors of bcr-abl kinase
Inventor: KOMPELLA AMALA KISHAN
IPC: C07D401/14
Filed: 2005-07-19
Abstract: The present invention relates to novel intermediates useful for the preparation of novel phenylaminopyrimidine derivatives, novel phenylaminopyrimidine derivatives. Pharmaceutical composition containing the novel phenylaminopyrimidine derivatives and processes for their preparation.  The invention particularly relates to novel Phenyl pyrimidine amine derivatives of the general formula (I). The novel compounds of the formula 1 can be used in the therapy of Chronic Myeloid Leukemia (CML). Since the IC50;  191 values of these molecules are in the range 0.1 to 10.0 nm, these novel compounds are potentially useful for the treatment of CML.
Patent CA-2591516-A1 (CA)
Title: An autonomous method for oral delivery of a healing substance to a target place in gastrointestinal tract of humans or animals
Inventor: STUKANOV IGOR
IPC: A61N7/00
Filed: 2007-05-02
Abstract: A method for oral delivery of new drugs, big molecules, proteins, and healing substances to a target place in the body, via digestive tract, using autonomous mobile self-controlled capsules with sensors.
Patent CA-2591673-A1 (CA)
Title: Compositions comprising extracts from sanguinaria or macleaya
Inventor: DI NICOLO PAOLA
IPC: A61K36/00
Filed: 2005-12-06
Abstract: Compositions containing: 1. Anthocyanosides, and/or 2. Procyanidins, 3.  Isoquinoline alkaloids extracted from Sanguinaria canadensis, Macleaya cordata or Macleaya microcarpa, and optionally 4. a Zanthoxylum bungeanum and/or Echinacea angustifolia lipophilic extract.
Patent CA-2593093-A1 (CA)
Inventor: VAN DEN BRINK ALEXANDER MAASSE
IPC: H01L39/22
Filed: 2005-12-30
Abstract: A structure comprising (i) a first information device, (ii) a second information device, (iii) a first coupling element and (iv) a second coupling element is provided. The first information device has at least a first lobe and a second lobe that are in electrical communication with each other. The second information device and has at least a first lobe and a second lobe that are in electrical communication with each other. The first coupling element inductively couples the first lobe of the first information device to the first lobe of the second information device. The second coupling element inductively couples the first lobe of the first information device to the second lobe of the second information device.
Patent CA-2600754-A1 (CA)
Inventor: HOYOS MAURICIO
IPC: G01N15/00
Filed: 2006-03-13
Abstract: La présente invention concerne un dispositif de séparation fluidique comportant : - au moins un microcanal (2) s'étendant suivant un axe longitudinal (X), le microcanal ayant une section transversale présentant un e largeur mesurée suivant un premier axe transversal et une épaisseur mesurée suivant un deuxième axe transversal (Z) perpendiculaire au premier, la large ur étant supérieure à l'épaisseur, le microcanal comportant, suivant le deuxièm e axe transversal, des parois inférieure (3) et supérieure (4), - au moins des première (7), deuxième (8) et troisième (9) entrées en communication fluidiq ue avec le microcanal (2), la deuxième entrée (8) étant disposée, suivant le deuxième axe transversal (Z), entre les première (7) et troisième (9) entrée s, - au moins des première (10) et deuxième (11) parois de séparation transversales, séparant les première et deuxième entrées, respectivement les deuxième et troisième entrées, les première et deuxième parois de séparation (10 ; 11) étant agencées de manière à ce que la deuxième entrée (8) soit séparée de chacune desdites parois inférieure (3) et supérieure (4) par une distance non nulle mesurée suivant le deuxième axe transversal (Z), la deuxième entrée (8) étant notamment adjacente à l'une au moins des parois de séparation.
Patent CA-2602718-A1 (CA)
Title: Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
Inventor: KINCAID JOHN
IPC: A01N43/40
Filed: 2006-03-24
Abstract: Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: (I) The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
Patent CA-2605906-A1 (CA)
Inventor: STOKES CASEY D
IPC: C10M145/02
Filed: 2007-10-04
Abstract: An oil-soluble lubricating oil additive composition prepared by the process which comprises reacting a copolymer, with at least one ether compound and with at least one aliphatic compound capable of reacting with at least one monocarboxylic acid or ester thereof, or dicarboxylic acid, anhydride or ester thereof.
Patent CA-2606026-A1 (CA)
Inventor: EUM JAY
IPC: A61B18/02
Filed: 2006-04-26
Abstract: The detachable cryosurgical probe includes a disposable probe assembly and a reusable probe assembly. The disposable probe assembly includes a breakaway collar (44) which, when twisted away, activates a finger lock element (24) which provides release of the disposable probe assembly from the reusable probe assembly. Additional features include a safety valve assembly for impeding cryogenic working fluid flow when the disposable probe assembly is detached from the reusable probe assembly and an electrical confirmation assembly for providing electrical confirmation that the disposable probe assembly is connected. Other embodiments include a sliding mechanism that allows for selectively positioning of the vacuum tube relative to the shaft to create an ice ball of the desired size and configuration.
Patent CA-2606204-A1 (CA)
Title: Cutting segment for cutting tool and cutting tools
Inventor: CHANG JOON-HO
IPC: B23D61/02
Filed: 2006-04-19
Abstract: The invention provides a cutting segment for a cutting tool for cutting or drilling a brittle work piece such as stone, bricks, concrete and asphalt, and a cutting tool having the cutting segment. The cutting segment includes a cutting surface for cutting a work piece and a plurality of abrasive particle layers. The abrasive particle layers are disposed perpendicular to a cutting direction. Each of the abrasive layers has a plurality of abrasive particle rows in a width direction of the cutting segment. Each of the abrasive rows has a plurality of abrasive particles arranged in a line. Further, the abrasive layers have a plurality of blank sections therebetween. In the blanks sections, abrasive particles are absent or have a concentration of 70% or less with respect to those in the abrasive rows. In addition, the blank sections include relatively thick blank sections and relatively thin blank sections.