baber/WOPTO huggingface dataset:
Patent MX-2018008237-A (MX)
Title: Detection method of the mirnas profile (mirnomes) in cancer and its use in the detection of new potential targets with therapeutic prospects.
Inventor: FRANCISCO JAVIER CAMACHO ARROYO
IPC: C12Q1/6886
Filed: 2018-07-02
Abstract: The present disclosure is related to simple and effective methods for detecting the characteristic miRNA profile (miRNOme) of various types of cancer. For example, retinoblastoma (Rb), that are useful for detecting novel potential targets with therapeutic prospect. In the present invention, the analysis of complete miRNOme expression of various clinical retinoblastoma samples using a high-performance platform is described. Includes 2578 mature miRNAs, which were analyzed using a platform that includes 2578 mature miRNAs, applying RMA analysis to normalize the raw data and obtaining categorical data from the detection values, and then use signal intensity data derived from the expression data. Likewise, molecular tools were used to find targets and map miRNAs to chromosomes. As a result, in all the analyzed cases, a core group of 30 highly expressed miRNAs and a group of 993 uniformly absent miRNAs was determined, while a further 1022 miRNAs were variably detected in the samples, reflecting heterogeneity between tumors. mRNAs targets, the pathways and biological processes affected by some of these miRNAs were explored, determining that the core group of 30 miRNAs represents the machinery common to all Rbs, and affects most routes considered cornerstones of cancer. In this core group, miR-3613 was identified as a critical negative regulatory potential node because it is highly expressed in all samples, and its potential mRNAs targets include at least 36 tumor suppressor genes, including the RB1 gene. In the variably expressed genes, 36 of them are differentially expressed between boys and girls, being its target routes associated with hormonal production. The results obtained with the method of the present invention, indicate that retinoblastoma samples share a miRNA profile apart from tumor heterogeneity, and they allow determining novel targets with therapeutic potential for the treatment of the disease. According to the present invention, the methodology described here may be potentially useful for determining the miRNOme of other cancers, in order to find therapeutic targets that may be useful for their treatment.
Patent MX-2018009258-A (MX)
Title: Cooling device for an electrical machine.
Inventor: GUILLAUME TAVERNIER
IPC: H02K9/19
Filed: 2017-01-24
Abstract: The invention relates to a cooling device (2) for an electrical machine (1), which is intended to be mounted in a moving assembly, said device comprising a dielectric liquid reservoir (4) secured to the casing (3) in a leak-tight manner, and comprising a dielectric liquid discharge pipe (10,10') extending through the reservoir (4) from a discharge port (8, 8') in the casing at one end of the reservoir to an opposite end (42, 41) of the reservoir (4).
Patent MX-2018010844-A (MX)
Title: Biological sampler, collector and storage container.
Inventor: ROY VICTOR BLADEN
IPC: A61B10/02
Filed: 2017-02-27
Abstract: The invention relates to, as an assembled elongate string, a sample collector and sample collector driver to drive at least the sample collector through an item to be sampled. The sample collector comprises a punch having a bore aligned to the elongate direction. One end of the punch and bore presents a cutter to cut and hold a sample from the item at the bore as the punch passes through the sample. The sample collector further comprises a plunger slideably supported to said punch to be able to move in said bore between a retracted position and an advanced position relative said punch. The movement of the plunger from the retracted position to the advanced position causes, in use, the cutter held sample to be displaced from the cutter. The sample collector driver comprises a body interfaced with said sample collector in a telescopic manner.
Patent MX-2018013112-A (MX)
Title: Adjustable dosing fluid dispenser for flexible fluid packages.
Inventor: ROGER J LAFLAMME
IPC: B65D35/08
Filed: 2017-04-27
Abstract: A device for dispensing fluid from a fluid container, the device capable of being set to different discrete and repeatable/equal dispensing amounts, depending on the amount of fluid required to be dispensed by the user for various applications and uses. The device may also be set to an off or closed position to prevent accidental dispensing of fluid when not in use. The device is preferably configured to be affixed to the outer surface of a fluid container, which fluid container is preferably a flexible bag or pouch.
Patent MX-2018015852-A (MX)
Title: Use of certain compounds to modify, reduce, or eliminate off-notes.
Inventor: NICOLE SCHULZE
IPC: A61K8/22
Filed: 2016-06-21
Abstract: The invention relates primarily to the use of one or more compounds having formula (I) XkYlZmOn, as described herein, to modify, reduce, or eliminate one or more off-note(s) of one or more substance(s) selected from the group (G1), as described herein, by chemically converting the one or more substance(s) of the group (G1) and thus modifying, reducing, or eliminating the one or more off-note(s), in a composition (Z1), which contains one or more substances selected from the group (G2), as described herein, in addition to one or more compounds of formula (I) and the one or more substances of the group (G1). The invention further relates to new methods for modifying, reducing, or eliminating one or more off-note(s) and new compositions obtained thereby.
Patent MX-2019000526-A (MX)
Title: Novel antibodies specifically binding to zika virus epitopes and uses thereof.
Inventor: DAVIDE CORTI
IPC: C07K16/10
Filed: 2017-07-12
Abstract: The invention relates to antibodies, and antigen binding fragments thereof, that potently neutralize infection of ZIKV. The invention also relates to antigenic sites to which the antibodies and antigen binding fragments bind, as well as to nucleic acids that encode and immortalized B cells that produce such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies and antibody fragments of the invention in screening methods as well as in the diagnosis, prophylaxis and treatment of ZIKV infection.
Patent MX-2019001282-A (MX)
Title: Mold and method for forming a molded part.
Inventor: Ray Melton LAZALIER
IPC: B29C33/00
Filed: 2017-07-31
Abstract: A mold includes a first mold portion, a second mold portion, and a projection. The second mold portion is secured against the first mold portion along a draw axis to form at least one mold cavity. The second mold portion includes an internal surface oriented at an oblique angle relative to the draw axis. The projection extends from the internal surface along a projection axis. The projection forms an elongated profile including a first end, a second ends, and a pair of side surfaces extending between the first end and the second end.
Patent MX-2019003164-A (MX)
Title: Pcd drill and manufacturing method for same.
Inventor: HIROYUKI FUKUSHIMA
IPC: B23B51/00
Filed: 2017-09-20
Abstract: When forming a first preliminary flute (70) on a PCD layer (22) of a columnar body (16), electrical discharge machining is performed by setting the electrode orientation so that the first twist angle is a. Next, when forming a second preliminary flute (74) on a substrate (20) of the columnar body (16) and a round bar (62), the grinding process is performed by setting the grinding orientation and direction for a diamond whetstone (72) so that a second twist angle (ß) is larger than the first twist angle (a).
Patent MX-2019003183-A (MX)
Title: Driving method and driving device of fluid pressure cylinder.
Inventor: KENGO MONDEN
IPC: F15B11/064
Filed: 2017-09-04
Abstract: A fluid pressure cylinder driving device (20, 20A to 20F) includes a switch valve (24), a high pressure air supply source (26), an exhaust port (28) and a check valve (30). When the switch valve (24) is at a first position, a head side cylinder chamber (42) communicates with the high pressure air supply source (26), and a rod side cylinder chamber (44) communicates with the exhaust port (28). When the switch valve (24) is at a second position, the head side cylinder chamber (42) communicates with the rod side cylinder chamber (44) via the check valve (30), and the head side cylinder chamber (42) communicates with the exhaust port (28).
Patent MX-2019003757-A (MX)
Title: Track nut with increased bearing area.
Inventor: MIRCEA DUMITRU
IPC: F16B37/00
Filed: 2017-10-09
Abstract: A track nut (200, 500) comprises a main body (202) defining a central aperture (204) with threads (206) disposed in the central aperture (204), the aperture (204) defining a cylindrical axis (A) and a radial direction (R), a first end (208, 508) and a second end (210, 510) disposed along the cylindrical axis (A), and wherein the first end (208 508) defines an at least partially circular perimeter (212) and the second end (210, 510) defines a generally polygonal perimeter (214) with a plurality of corners, the polygonal perimeter (214) including at least one variable blend portion (218).
Patent MX-2019006512-A (MX)
Title: Imprinting apparatus.
Inventor: ANDREW A BROWN
IPC: G03F7/00
Filed: 2017-12-19
Abstract: An imprinting apparatus includes a silicon master having a plurality of nanofeatures defined therein. An anti-stick layer coats the silicon master, the anti-stick layer including a molecule having a cyclosiloxane with at least one silane functional group. A method includes forming a master template by: depositing a formulation on a silicon master including a plurality of nanofeatures defined therein, the formulation including a solvent and a molecule having a cyclosiloxane with at least one silane functional group; and curing the formulation, thereby forming an anti-stick layer on the silicon master, the anti-stick layer including the molecule. The method further includes depositing a silicon-based working stamp material on the anti-stick layer of the master template; curing the silicon-based working stamp material to form a working stamp including a negative replica of the plurality of nanofeatures; and releasing the working stamp from the master template.
Patent MX-2019006710-A (MX)
Title: Elastomeric compositions comprising silicate fibres with needle-shaped morphology of nanometric size and tyres for vehicles that comprise them.
Inventor: LUCA GIANNINI
IPC: C08L7/00
Filed: 2017-12-18
Abstract: The present invention regards a solid master elastomeric composition (masterbatch, MB) comprising silicate fibres with needle-shaped morphology of nanometric size, characterised by high fibre content and uniformity, a process advantageous for the preparation thereof and its use in manufacturing tyres for vehicles. Advantageously the present elastomeric composition allows minimising the drawbacks associated with the handling of the powdery fibres in the manufacturing of compounds for tyres, without altering the final performances thereof.
Patent MX-2019007275-A (MX)
Title: Oral care article comprising a container.
Inventor: XIAOJIE GENG
IPC: B65D5/68
Filed: 2016-12-21
Abstract: An oral article comprising a six sided carton (suitable for containing a tube of dentifrice) having a front-top flap that is unfolded open along a line of weakness, wherein at least a portion of the line of weakness includes a 1/2 cut line of weakness on the top side of the carton.
Patent MX-2019008812-A (MX)
Title: An automatic and interactive back door.
Inventor: JAIME CUBEIRO MARTINEZ
IPC: E06B9/72
Filed: 2019-07-24
Abstract: The present invention relates to an automatic and interactive back door, which consists of a support structure configured to mount a rotating shaft with rolling means fixing a roller blind. Said rotary shaft houses a tubular motor with at least one pair of adapters that make contact and interact with said shaft. Also, it includes an electronic control system activating in one direction or another, the tubular motor for rotating the rotary-axis and opening or closing the roller blind, and elements for its manual activation.
Patent MX-2019009206-A (MX)
Title: An improved bar conveyor.
Inventor: LEOPOLDO LAGO
IPC: B65G17/06
Filed: 2018-02-20
Abstract: A continuous bar conveyor for the food industry, of the type comprising: - a plurality of bars (2), constrained at the ends with chains (4) having links (6) configured so as to be engageable by motorized toothed wheels, serving the object of moving the conveyor along fixed guides, - a plurality of spirals (1 0) wrapping said bars (2) in pairs, said links (6) of said chains (4) and said spirals (10) being configured so as to limit the maximum distance between adjacent bars (2), but so as to allow their reciprocal movement together, characterized in that, between adjacent successions of at least two bars (2), wrapped by a spiral (1 0), it comprises at least one bar (2'), which is not wrapped by spirals (10), and to which a sheet (22) of plastic food material is constrained, having elevated resistance to the operating temperature of said conveyor and a smooth, non-stick surface, said sheet (22) resting on the upper surface defined by said spirals (1 0) and with a dimension in the advancing direction of the conveyor smaller than the distance between successive bars (2') not wrapped by spirals (10).
Patent MX-2019011601-A (MX)
Title: In-ground enclosure system.
Inventor: KEVIN T AYCOCK
IPC: H04B7/26
Filed: 2018-04-03
Abstract: An in-ground enclosure for housing electrical components is provided. The in-ground enclosure can include an outer shell, a first compartment located within the outer shell, a second compartment located within the outer shell, an upper panel comprising a first compartment opening for accessing the first compartment and a second compartment opening for accessing the second compartment, a dividing wall separating the first compartment from the second compartment, a first compartment cover adapted for removably sealing the first compartment opening, and a second compartment cover adapted for removably sealing the second compartment opening. A telecommunications base station is also provided. The telecommunications base station can include an in-ground enclosure and a cellular base station, which can include an antenna coupled to signal processing equipment and a power supply.
Patent MX-2019012216-A (MX)
Title: Plant and process for multi-mode manufacturing of metal strips and plates.
Inventor: ANDREA TEODORO BIANCHI
IPC: B21B1/46
Filed: 2018-04-09
Abstract: A plant for the endless or batch production of strips and plates of hot-rolled steel, with thickness from 0,6 mm to 50 mm, comprises a continuous caster (1) of thin slabs with liquid core reduction, followed by an induction heater (2), with a first shear (3) therebetween, and then a rolling mill (4) followed by a second shear (5) and a run out table with a cooling device (6) and a pusher/piler (7) for plates and then a third shear (8) and a plurality of coilers (9), and it further includes a minimum-reduction rolling stand (10) arranged between the continuous caster (1) and the first shear (3), said minimum- reduction rolling stand (10) being designed to perform a slab thickness reduction of only about 10% and in any case not more than 20%.
Patent MX-2020004984-A (MX)
Title: Glass containers with improved strength and improved damage tolerance.
Inventor: TIMMONS CHRISTOPHER LEE
IPC: C03C17/00
Filed: 2015-05-29
Abstract: The glass containers described herein have at least two performance attributes selected from resistance to delamination, improved strength, and increased damage resistance. In one embodiment, a glass container may include a body having an inner surface, an outer surface and a wall thickness extending between the outer surface and the inner surface. A compressively stressed layer may extend from the outer surface of the body into the wall thickness. The compressively stressed layer may have a surface compressive stress greater than or equal to 150 MPa. A lubricous coating may be positioned around at least a portion of the outer surface of the body. The outer surface of the body with the lubricous coating may have a coefficient of friction less than or equal to 0.7.
Patent MX-2020005316-A (MX)
Title: Piston with flexible closure for aerosol container.
Inventor: BENSON WILLIAM MERCER
IPC: B65D83/42
Filed: 2018-11-01
Abstract: The invention relates to a piston for an optionally pressurized container, the piston having a sidewall, an upper side and a bottom side, and at least a first circumferential seal, wherein at least the upper side of the piston is closed by a closure and made of a first elastic material, wherein the upper side is configured to deform upon a pressure change acting on the upper side, wherein the sidewall is made of a second material which is different from the first elastic material, wherein the first circumferential seal is positioned on the sidewall on its outer surface. The invention further relates to an optionally pressurized container comprising a piston as mentioned above, to a process of discharging a product from said container and to a process of manufacturing said container.
Patent MX-2020008633-A (MX)
Title: Collapsible handle for a tool.
Inventor: STANISZEWSKI MEGAN
IPC: F16C11/10
Filed: 2019-02-19
Abstract: A foldable handle for long-handled tools includes first and second handle members hingedly coupled together at their respective coupling ends by a toggle linkage. The linkage is pivotably coupled to each of the handle members via first and second pivot pins respectively forming a double-jointed articulating joint. The joint includes multiple locking features which cooperate to form a rigid and anti-rotational joint when the handle members are in a coaxially- aligned operational unfolded condition. The linkage includes oppositely extending arm portions slideably insertable into complementary configured locking axial passages in the hinge members. Each handle member includes a plurality of mutually interlocking axial protrusions. The linkage includes a block-shaped middle portion between the arms which lockingly engage a transverse channel in each end of the handle members. Finally, a slideable collar covers the joint and threadably engages one of the handle member to conceal and secure the joint.
Patent MX-2020009586-A (MX)
Title: SUBSTITUTED (2-AZABICYCLO [3.1.0] HEXAN-2-YL) PYRAZOLO [1, 5-a] PYRIMIDINE AND IMIDAZO [1, 2-b] PYRIDAZINE COMPOUNDS AS TRK KINASES INHIBITORS.
Inventor: ZHAO XINGDONG
IPC: C07D519/00
Filed: 2019-03-13
Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
Patent MX-2020009644-A (MX)
Title: Data processing method, access network device, and core network device.
Inventor: LIU JIANHUA
Filed: 2018-11-20
Abstract: Disclosed are a data processing method, an access network device, and a core network device. The method comprises: the access network device receives first information sent by the core network device or a terminal device; the access network device determines, according to the first information, whether to perform security processing on data to be processed. By means of the method, the access network device, and the core network device in the embodiments of the present application, the data transmission performance can be improved.
Patent MX-2020009964-A (MX)
Title: Bordetella pertussis-derived protein-obtaining method including affinity chromatography process.
Inventor: AHN DONG HO
IPC: C07K14/235
Filed: 2019-03-15
Abstract: The present invention relates to a Bordetella pertussis-derived protein-obtaining method including an affinity chromatography process. The present invention increases the production yield of PT and FHA proteins by isolating PT and FHA proteins of Bordetella pertussis through a purification process using a blue affinity column. In addition, when used, the filtration process can remarkably increase the output of the target proteins, compared to an isolation method using a size exclusion chromatography (SEC) process. Furthermore, the method using the blue affinity column for isolation of PT and FHA proteins decreased resin expense, process time, buffer consumption, and production cost and significantly increased the productivity of PT and FHA proteins.
Patent MX-2020009983-A (MX)
Title: A mattress with an integrated mattress adjustment apparatus.
Inventor: DAN ON JOSHUA
IPC: A47C21/04
Filed: 2019-03-24
Abstract: An adjustable mattress frame suitable to be fully contained within a mattress is provided with a central body segment and with upper and lower body adjustable segments pivotally connected by one or more hinges to said central body segment, said central body segment being provided with one or more actuation modules suitable to actuate said upper and lower body segments respectively.
Patent MX-2020011195-A (MX)
Title: Absorbent article.
Inventor: SMET STEVEN
IPC: A61F13/539
Filed: 2019-04-24
Abstract: An absorbent article comprising a liquid pervious topsheet, a liquid impervious backsheet, and an absorbent core positioned between the liquid pervious topsheet and the liquid impervious backsheet; said absorbent article having a first and second longitudinal edge and a first and second transverse edge; wherein the absorbent core comprises a bottom core wrap sheet, absorbent material, and a liquid management structure, wherein the absorbent material is positioned directly between the bottom core wrap sheet and the liquid management structure; and wherein the liquid management structure covers at least a surface portion of the absorbent material and comprises at least one channel portion forming at least one channel zone in the absorbent core.
Patent MX-2020013209-A (MX)
Title: Herbicidal compositions.
Inventor: SENGUPTA ASHOKE K
IPC: A01P13/00
Filed: 2019-06-05
Abstract: The present invention relates to various pesticidal compositions including non-water-continuous herbicidal dispersion compositions and processes for preparing these compositions. The present invention further relates to herbicidal application mixtures including water continuous dispersion compositions, processes for preparing these application mixtures, and various methods of use. Further, the present invention relates to various herbicidal compositions having improved application properties.
Patent MX-2020013614-A (MX)
Title: Methods and compositions for treating and/or preventing the progression and/or onset of age-related neurodegeneration.
Inventor: ZASLOFF MICHAEL
IPC: A61K31/575
Filed: 2019-06-13
Abstract: This invention relates to methods of treating and/or preventing the progression and/or onset of age-related neurodegeneration. The invention also relates to methods of reversibly slowing the growth and/or aging of a subject, and/or extending the potential lifespan of the subject, comprising administration of the naturally occurring aminosterol MSI-1436, or derivatives or salts thereof. Also described are methods of treating, preventing or delaying the onset of age- related diseases or conditions comprising administration of Aminosterol 1436, or derivatives or salts thereof.
Patent MX-2021002353-A (MX)
Title: Metal one piece slide and pull for slide fastener.
Inventor: SHAH NIRAV ASHOK
IPC: A44B19/26
Filed: 2019-08-28
Abstract: The invention involves a slide assembly (10) for a zipper. The slide assembly is formed in a single die cast operation to include the slide member (12) and the pull member (14) being formed simultaneously. Portions of the bridge (16) and pull member (14) are formed to provide a first side to side angle of pull when the pull member cooperates with the first end (18) of the bridge, and a second side to side angle of pull when the pull member cooperates with the second end (20) of the bridge.