baber/WOPTO huggingface dataset:
Patent NZ-543538-A (NZ)
Title: Apparatus and method for risk stratification of patients with chest pain of suspected cardiac origin
Inventor: CROSBY PETER
IPC: A61B/
Filed: 2004-05-05
Abstract: A method for risk stratification of a patient having acute cardiac ischemia, acute coronary syndrome, stable angina or unstable angina, comprising the steps of : a) receiving a result from at least a first in vitro diagnostic assay on a sample, the assay being for albumin that has been modified by exposure to ischemic tissue; b) receiving a result from an electrocardiogram (ECG) of the patient; and c) combining the results of the assay in step (a) and the electrocardiogram in step (b) using an algorithm to provide a risk stratification of the patient having the clinical condition. Also provided is an apparatus for diagnosis of a clinical condition or estimating the probability of the presence of the condition in a patient, comprising: an electronic module housing comprising a display means; a data entry and control means; a means for measuring an electrocardiogram (ECG); an aperture containing a reader means; an analysis means in electrical continuity with the data entry and control means, the ECG means, and the reader means, whereby the analysis means can analyze signals from each the means; a power source; and optionally a link to a laboratory or hospital information system; wherein the aperture is adapted to receive a sample analysis strip for conducting an in vitro diagnostic assay on a patient sample of a substance stream, and the reader is adapted to read results of the assay; whereby the analyzer receives signals from the ECG means and the data entry and control means, and upon insertion of the strip into the aperture, from the reader means, and the analyzer means transmits analyzed results to the display means.
Patent NZ-544079-A (NZ)
Title: Biologically active peptides consisting of SEQ ID 4 that modulate immune activity and growth of cancer
Inventor: WONG WAI MING
IPC: C07K5/083
Filed: 2002-07-11
Abstract: A substantially pure and biologically active peptide known as SEQ ID 4 (VAPEEHPTLLTEAPLNPK). This includes a nucleic acid that has a sequence coding for this biologically active peptide and a pharmaceutical formulation produced therefrom. This peptide has the ability to modulate immune activity and growth of cancer, specifically liver cancer and melanomas. This peptide can also have a secretory signal peptide for secretion of the protein from the micro-organism in which it is expressed.
Patent NZ-546259-A (NZ)
Title: Benzoimidazole compounds
Inventor: ARIENTI KRISTEN L
IPC: C07D401/12
Filed: 2004-09-29
Abstract: Disclosed is a compound of formula (II) wherein X is N; Y is O, NR12, or CR12R13; Z is CR14; n is 1; and wherein the rest of the substituents are disclosed within the specification. Also disclosed is the use of at least one modulator selected from the above compounds in the preparation of a medicament for modulating an H4 receptor.
Patent NZ-551832-A (NZ)
Title: Neural stem cells
Inventor: CONTI LUCIANO
IPC: A61K35/12
Filed: 2005-06-09
Abstract: Provided is a method of obtaining and maintaining a transfected population of symmetrically dividing neural stem cells, the method comprising: (a) transfecting ES cells with a construct encoding a selectable marker A, wherein said ES cells are not totipotent human ES cells and wherein said selectable marker A is expressible under the control of a neural stem cell-specific promoter; (b) promoting differentiation of the ES cells to neural stem cells; (c) selecting for cells that express the selectable marker A, wherein at least 80% of the selected cells are symmetrically-dividing neural stem cells and wherein no more than I% of the selected cells are positive for the expression of markers for mature astrocytes, neurons or oligodendrocytes; and (d) culturing the selected cells attached to a substrate in a medium containing: (i) an activator of a signalling pathway downstream from a receptor of the EGF family; and (ii) an activator of a signalling pathway downstream from an FGF receptor. Further provided are neural stem cell lines obtained by the method.
Patent NZ-551851-A (NZ)
Title: Ostomy coupling
Inventor: BLUM JOHN L
Filed: 2006-12-06
Abstract: A controlled evacuation ostomy appliance comprising: (a) an appliance-side coupling member comprising a plurality of fastener lugs for fastening engagement with a body-side coupling member; (b) a housing member; and (c) a housing fastener for releasably fastening the housing to the appliance-side coupling member. The housing member is configured such that, when the housing member is fastened to the appliance-side coupling member, the housing member directly or indirectly braces the fastener lugs of the appliance-side coupling member to limit flexing of the lugs.
Patent NZ-556606-A (NZ)
Title: Collapsible combination ladder with telescopic legs one ladder section having wider steps than the other
Inventor: ERIKSSON PER-OLOF
IPC: E06C1/12
Filed: 2006-02-01
Abstract: A collapsible stepladder (1) is disclosed. The ladder has two ladder sides (2, 3), where the legs (2, 3) are connected to each other at one end by a hinge (5). Each of the ladder sides (2, 3) comprises several ladder sections (4a-4d), and each section comprises two ladder bars arranged parallel to each other and interconnected at one end by a rung to form a U-shaped ladder section. The ladder sections are telescopically inserted into a lower ladder section (4e) to form a collapsible ladder comprising at least three ladder sections. One of the ladder sides (3) is provided with a support part (12) in one end. The support part (12) is telescopically extendible from the ladder side (3) and forms an extension ladder of the ladder side and where the support part (12) projects above the hinge (5) between the two ladder legs (2, 3). The ladder may open out to be used as a straight ladder. The rungs on the one ladder side (2) ad narrower than the rungs on the other ladder side (3).
Patent NZ-556718-A (NZ)
Title: Method for determining responsiveness to CHKI inhibitors
Inventor: BERGERON LOUISE
IPC: A61K31/4985
Filed: 2006-02-16
Abstract: Disclosed is a method for determining if a CHK-1 inhibitor is inhibiting its molecular target CHK-1 in a cancer patient that has received a DNA damaging agent and a CHK-1 inhibitor by determining the presence of phosphorylated CHK-1, H2AX or determining the presence of a foci that is detected by the presence of MRE11, BRCA1, RAD51, 53BP1 and NBS1.
Patent NZ-561981-A (NZ)
Title: Feeding bottle teat with a one-way valve for venting
Inventor: SAMSON ILAN ZADIK
Filed: 2005-03-31
Abstract: A teat for a feeding bottle having a one-way valve 16 located remotely from the nipple of the teat to allow air to enter the feeding bottle to replace liquid sucked out of the bottle through the nipple while preventing liquid from leaking from the bottle, wherein the one-way valve 16 comprises an inwardly-oriented depression having opposed mutually inclined side walls 16a and 16b meeting along a ridge having a slit, characterised in that, when undeflected, the side walls 16a and 16b make line contact with one another at the ridge and in that the thickness of the side walls 16a and 16b is less than 0.4 mm whereby when acted upon by an increased pressure in the feeding bottle the side walls 16a and 16b collapse against one another and make sealing contact on an interface surface that extends from the ridge in the direction away from it.
Patent NZ-561997-A (NZ)
Title: Effluent disposal
Inventor: LEWIS LINDSAY RONALD
Filed: 2007-09-26
Abstract: In, or for, a dairy effluent disposal system, a separation means comprising or including a storage reservoir to receive dairy effluent and a liquid outtake from the storage reservoir; wherein at least one upright weeping wall, through which liquid can weep, defines a zone from which there is a liquid outflow for reticulation to on ground and/or on pasture disposal. The at least one weeping wall holds, or is adapted to hold, solids of sufficient size from the zone having said liquid outtake.
Patent NZ-568739-A (NZ)
Title: Therapeutic methods for inhibiting tumor growth with delta-like ligand 4 antagonists
Inventor: NOGUERA IRENE
IPC: A61K39/00
Filed: 2006-12-15
Abstract: Disclosed is the use of a delta-Iike ligand 4 (Dll4) antagonist in combination with a vascular endothelial growth factor (VEGF inhibitor) in the manufacture of a medicament for inhibiting tumor development or growth, wherein the Dll4 antagonist is an antibody or antibody fragment which specifically binds Dll4, or a fusion protein comprising an extracellular domain of Dll4 and a human Fc domain.
Patent NZ-571943-A (NZ)
Title: Process for the reduction of aldehyde concentration in a target stream using a supported catalyst reaction
Inventor: KIMMICH BARBARA F M
IPC: C07C53/08
Filed: 2007-04-03
Abstract: Disclosed is a process for reducing an aldehyde concentration comprising providing a target stream that comprises a carbonylatable reactant and a first aldehyde concentration; and subjecting the target stream to a reaction comprising a supported catalyst that comprises at least one Group 8 to Group 11 metal at conditions sufficient to reduce the first aldehyde concentration to a second aldehyde concentration.
Patent NZ-580661-A (NZ)
Title: Apparatus for cooling a bag of fluid employing a multi-spike adapter
Inventor: MACLER JEFFREY
IPC: B67D99/00
Filed: 2007-07-03
Abstract: Disclosed is a system for dispensing fluids (200) wherein a support structure (206) holds bulk fluid contained within a collapsible bag (210) that is transferred from the bag to an enclosed chamber (202) in a dispensing base. The system includes a plurality of spikes (316, 317) situated to puncture the bag when the bag is supported by the support structure. The plurality of spikes provides continuity of air and fluid flow between the chamber and the bag upon puncturing the bag. The fluids are dispensed from the enclosed chamber, preferable with the use or a dispensing valve.
Patent NZ-587314-A (NZ)
Title: Poly hydroxyl alkyl phosphine-organic silicon tanning agent, its preparation and application in fur tanning
Inventor: YANG YINGYONG
IPC: C08L83/05
Filed: 2009-02-24
Abstract: Disclosed is a silicon tanning agent comprising: i. hydroxylalkyl phosphine, or tetra(hydroxyl methyl) phosphine salt, ii. organic silicon (silicone) of molecular mass range 10,000-200,000, iii. surface active agent (surfactant), iv. stabilizer and v. pure water The silicon tanning agent is useful for tanning fur or pelts, especially woolskin or woolfell.
Patent NZ-589897-A (NZ)
Title: Device for enabling access to a wind turbine rotor blade which can be guided to the blade
Inventor: TEICHERT PAUL
IPC: E04G3/24
Filed: 2009-06-18
Abstract: Disclosed is a device (1) for enabling access to a rotor blade of a wind turbine. The device is adapted for being moved in the longitudinal direction of the rotor blade. The device has a frame structure (2); means for supporting and guiding the device in relation to the rotor blade (8, 10); and means for lowering and/or lifting the device in relation to the rotor blade (20, 22). The means for supporting and guiding the device in relation to the rotor blade are configured for contacting the rotor blade at regions at or near the front edge and/or rear edge of the rotor blade. The means for supporting and guiding the device in relation to the rotor blade can be adjusted to the rotor blade during movement of the device in order to maintain controllable contact at the contact regions. The means for supporting and guiding the device in relation to the rotor blade comprises a plurality of contact means (12, 14). At least one of the contact means is omnidirectionally movable along the surface of the rotor blade while the means for supporting and guiding the device are being adjusted to the rotor blade during movement of the device.
Patent NZ-596617-A (NZ)
Title: Melanocortin receptor-specific peptides
Inventor: SHI YI-QUN
IPC: C07K7/56
Filed: 2010-06-07
Abstract: 596617 Disclosed are melanocortin receptor(MC4-R)-specific cyclic peptides. For treating MC4-R mediated conditions such as erectile disfunction. The melanocortin receptor-specific cyclic peptides are of the formula (I) where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and z are as defined in the specification, compositions and formulations including the peptides of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes. The cyclic peptides also conform to the formula Z-Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Y, which is an amino acid sequence as defined in the specification, with exemplified compounds including: Ac-Arg-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-NH2 Ac-Arg-cyclo(Asp-Ser-D-Phe-Arg-Trp-Lys)-NH2 Ac-Arg-cyclo(Asp-Ala- D-Phe-Cit-Trp-Lys )-NH2 Ac-Arg-cyclo(Asp-His-D-Phe-Lys-Trp-Lys)-NH2 Ac-Arg-cyclo(Asp-Lys- D-Phe-Lys-Trp-Lys)- NH2 Ac-Arg-cyclo(Asp-Nle- D-Phe-Arg-Trp-Lys)- NH2 Ac-Arg-cyclo(Asp-Thr(Bzl)-D-Phe-Arg- Trp-Lys)-NH2 and Ac-Arg-cyclo(Asp-lle-D-Phe-Arg-Trp-Lys)-NH2
Patent NZ-615517-A (NZ)
Title: A wireless code game enuresis alarm for the treatment of enuresis
Inventor: WICKHAM GEOFFREY GORDON
IPC: A61F5/48
Filed: 2009-09-22
Abstract: Disclosed is a system for use by a subject with a sleep disorder. The system includes at least one sensor that detects at least one attribute of the sleep disorder and outputs at least a first signal on or after detection of the attribute. The system also includes a control device (12) that is comprised of an arousal device (not shown), an interactive device (15) and an output device (19). The arousal device activates on or after receipt of the first signal by the control device (12). The interactive device (15) is actuable by the subject to deactivate or modify the operation of the arousal device. The output device (19) is configured to deliver an output to the subject on or after deactivation or modification of the arousal device. The output device (19) on each operation delivers an output that is different from that delivered the immediately previous time.
Patent NZ-617502-A (NZ)
Title: Acoustic detection for respiratory treatment apparatus
Inventor: HOLLEY LIAM
IPC: A61M16/00
Filed: 2010-02-10
Abstract: Disclosed is an apparatus (102). The apparatus (102) includes a sound conduit (108) adapted to direct an acoustic signal (A1) to an anatomical cavity of a user of the apparatus (102). A sound generator generates the acoustic signal and a microphone, which is coupling with the sound conduit (108), generates a measure of the acoustic signal (A1). A processor analyses data samples of the measure of the acoustic signal (A1) from the microphone by calculation of a cepstrum with the data samples of the measure of the acoustic signal (A1). The processor then determines that the user is a pre-authorised user based on the analysis.
Patent NZ-621356-A (NZ)
Title: Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence
Inventor: JOHNSON BANKOLE A
IPC: C12Q1/68
Filed: 2011-07-01
Abstract: Disclosed is the use of a composition, comprising: a therapeutically effective amount of an antagonist of the serotonin receptor 5-HT3, odansetron for the manufacture of a medicament for the treatment of an addictive disease or disorder in a patient, wherein the patient’s serotonin transporter gene SLC6A4 is known to have: (a) the GG genotype of rs1176713; (b) the GG genotype of rs1176713 and at least one genotype selected from: i. the LL genotype of 5-HTTLPR; and, ii. the TT genotype of rs1042173; (c) the GG genotype of rs1176713 and at least one genotype selected from: i. the AC genotype of rs17614942; and, ii. the LL genotype of 5-HTTLPR; (d) the GG genotype of rs1176713 and at least one genotype selected from: i. the AC genotype of rs17614942; and, ii. the TT genotype of rs1042173; or (e) the GG genotype of rs1176713 and at least one genotype selected from: i. the AG genotype of rs1150226; and, ii. the TT genotype of rs1042173.
Patent NZ-623880-A (NZ)
Title: Cover assembly
Inventor: ERRON LEE
IPC: F16B5/00
Filed: 2014-04-15
Abstract: Disclosed is a cover sealing strip assembly for use with a wall cladding assembly having one or more panels to cover or weatherproof the joint between two wall panels. The cover assembly includes a base comprising a base member for attachment to a building structure so as in use to be positioned proximate an edge portion of at least one of the panels of the walling assembly. A base attachment formation extends outwardly from the base member; and an elongate cover has a cover portion to extend longitudinally along the edge portion and has a transverse width, along with a cover attachment formation extending outwardly from the cover portion. The cover attachment formation is adapted to be attached to the base attachment formation to retain the cover portion in a position overlapping the edge portion. The base attachment formation comprises a base stem and a male attachment outwardly extending from the base stem and the cover attachment formation comprises a cover stem and a female attachment outwardly extending from the cover stem. The base male attachment formation is adapted to be attached to the female attachment. The cover portion is adapted to be coextensive with the base member when attached thereto. The male attachment and the female attachment are adapted to be attached in a snap-fit.
Patent NZ-629032-A (NZ)
Title: Crystalline form of 3-(3-{ 2-[(e)-3,5-diamino-6-chloro-pyrazine-2-carbonylimino]-1,3,8-triaza-spiro[4.5]decane-8-carbonyl} -benzenesulfonylamino)-propionic acid dipropylcarbamoylmethyl ester succinate
Inventor: TUFILLI NICOLA
IPC: C07D471/10
Filed: 2013-03-15
Abstract: Disclosed is crystalline form C of the spirocyclic amiloride derivative: 3-(3-{ 2-[(E)-3,5-diamino-6-chloro-pyrazine-2-carbonylimino]-1,3,8-triaza-spiro[4.5]decane-8-carbonyl} -benzenesulfonylamino)-propionic acid dipropylcarbamoylmethyl ester succinate salt, wherein Form C is characterized by an X-ray powder diffraction pattern comprising six or more 2-theta values selected from the group of 7.0°±0.2, 10.6°±0.2, 14.3°±0.2, 18.2°±0.2, 18.6°±0.2, 19.2°±0.2, 21.2°±0.2, 21.8°±0.2, 24.7±0.2, 29.0°±0.2 and 31.5°±0.2 at a temperature of 21-26°C, for use in the treatment of respiratory diseases, such as cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease (COPD), asthma, respiratory tract infections (acute and chronic; viral and bacterial) and lung carcinoma. Further disclosed is an inhalation device that contains and is adapted to deliver the crystalline form of the compound as defined above by pulmonary administration.
Patent NZ-630536-A (NZ)
Title: Therapeutic agent or prophylactic agent for dementia
Inventor: MORI HIROSHI
IPC: C12P21/08
Filed: 2013-05-30
Abstract: Disclosed are antibodies that participate in antigen-antibody reactions with tau a protein that has been phosphorylated on the amino acid residue at position 413 of the tau protein represented by SEQ ID NO:1 and the use of such antibodies in the manufacture of a medicament for the therapeutic or prophylactic treatment of cognitive disorders (sequence as disclosed in the specification).
Patent NZ-702227-A (NZ)
Title: Biogas residue-containing formula feed for chicken
Inventor: YU FANGBO
IPC: A23K10/38
Filed: 2014-04-02
Abstract: Biogas residue-containing formula feed for chicken is formed by mixing a component A and a component B. The component A is formed by mixing the following raw materials: a biogas residue, an astragalus residue, Caulis perillae, Eucommia ulmoides, pigweed, and a premixture. The biogas residue is the resultant obtained after anaerobic fermentation of an alcohol-making mixture using cassava or sweet potatoes as raw materials for fermentation, and the resultant is dewatered by adopting mechanical extrusion, exposed in the sun and dried, and then ground by a grinder. The component B is formed by mixing the following raw materials: maize, soybean meal, dicalcium phosphate, calcium carbonate, and table salt.
Patent NZ-704055-A (NZ)
Title: Media insertion system
Inventor: MURRET-LABARTHE HERVE
IPC: H04N21/81
Filed: 2010-08-02
Abstract: A media insertion method in which programming is received by a programme receiver and is output substantially immediately by the receiver and/or recorded at the receiver for subsequent output is disclosed. The programming having a break defined therein such that media stored at the receiver is selectively output during normal playback of the break. The programming recorded by the receiver includes a substitutional schedule identifying the media possible to be selected for output within normal playback of the break.
Patent NZ-706401-A (NZ)
Title: Carboxamide compounds and their use as calpain inhibitors
Inventor: HUTCHINS CHARLES W
IPC: C07D239/10
Filed: 2010-05-06
Abstract: Disclosed herein are carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). Additionally disclosed is the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity, interleukin-I, TNF or Aβ level, such as malaria, HIV or disorders associated with the kidneys. The carboxamide compounds are compounds of the general formula (I) in which R1, R2, R3a, R3b, Q, Y, A and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof. In particular, the compounds have the general formula (Ia) and (Ib) in which R1, r, R2b, R3a, R3b, R4, Y and X have the meanings mentioned in the claims, including the tautomers thereof and the pharmaceutically suitable salts thereof.
Patent NZ-716840-A (NZ)
Title: Combination formulation of two antiviral compounds
Inventor: GORMAN ERIC
IPC: A61K31/513
Filed: 2014-01-30
Abstract: Disclosed are pharmaceutical compositions comprising Compound I, having the formula (I): and an effective amount of sofosbuvir wherein the sofosbuvir is substantially crystalline. Also disclosed are methods of use for the pharmaceutical composition.
Patent NZ-718896-A (NZ)
Title: Methods for improving diaphragm function
Inventor: JASPER JEFFREY R
IPC: A61P21/00
Filed: 2013-04-01
Abstract: Provided are compositions and methods for improving diaphragm function in a patient by administering to the patient an effective amount of a skeletal muscle troponin activator or a pharmaceutically acceptable salt thereof.
Patent NZ-719421-A (NZ)
Title: Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos
Inventor: ZOHAR YONATHAN
IPC: A01K61/00
Filed: 2014-11-14
Abstract: Methods for the production of reproductively sterile fish and aquatic animals for aquaculture, the aquarium trade, and control of invasive species are described. The methods include disruption of gonadal development through the administration of compounds that lead to the failure of fertile gonadal development. Compounds may be delivered to the eggs prior to fertilization or water activation or post fertilization and water activation by contacting unfertilized or pre-water- activated fertilized eggs or fertilized eggs in an immersion medium including the compound of interest. Compounds may be conjugated with a molecular transporter compound effective for chorionic transport of the conjugate. The compounds may be antisense Morpholino oligomers that are capable of effectively suppressing the expression of the dead end gene or other essential genes for germ cell development in fish and other egg-producing aquatic animals.