baber/WOPTO huggingface dataset:
Patent CA-2967277-A1 (CA)
Title: Assessment of suture or staple line integrity and localization of potential tissue defects along the suture or staple line
Inventor: KRIMSKY WILLIAM S
IPC: A61B5/00
Filed: 2017-05-15
Abstract: A method for assessing suture line integrity includes loading a navigation plan into a navigation system, the navigation plan including a planned pathway shown in a 3D model, inserting a probe into a patient's airways, the probe including a location sensor in operative communication with the navigation system, registering a sensed location of the probe with the planned pathway, and selecting a target in the navigation plan, the target including a proposed suture line. The method further includes presenting a view of the 3D model showing the planned pathway and indicating the sensed location of the probe, navigating the probe through the airways of the patient's lungs toward the target, and imaging the proposed suture line of the target, via the probe, to determine tissue integrity surrounding the proposed suture line.
Patent CA-2968933-A1 (CA)
Title: Peptides for use in neurodegenerative disorders
Inventor: GREENFIELD SUSAN ADELE
IPC: C07K7/06
Filed: 2015-11-26
Abstract: The invention relates to novel peptides, compositions, therapies and methods for treating neurodegenerative disorders, for example Alzheimer's disease.
Patent CA-2969471-A1 (CA)
Inventor: SULLIVAN BRIAN FRANCIS
IPC: G01N33/15
Filed: 2015-12-14
Abstract: Provided herein are methods for determining the functional status of a cellular pathway in a diseased cell sample obtained from an individual subject. These methods involve contacting a diseased cell sample obtained from the subject with a perturbing agent (e.g., an activating agent) known to perturb a specific cellular pathway when the pathway is functioning normally. A change in one or more physiological response parameters in the presence of the perturbing agent indicates that the cellular pathway targeted by the perturbing agent is functional in the individual subject. Methods of selecting a targeted therapeutic agent for an individual subject are also provided.
Patent CA-2969740-A1 (CA)
Inventor: RUBIN GREGORY ALAN
IPC: H04L9/08
Filed: 2015-12-14
Abstract: A cryptography service allows for management of cryptographic keys and for the evaluation of security expectations when processing incoming requests. In some contexts, the cryptography service, upon receiving a request to perform a cryptographic operation, evaluates a set of security expectations to determine whether the cryptographic key or keys usable to perform the cryptographic operation should be trusted. A response to the request is dependent on evaluation of the security expectations.
Patent CA-2972787-A1 (CA)
Title: Synthetic rigidin analogues as anticancer agents, salts, solvates and prodrugs thereof, and method of producing same
Inventor: MAGEDOV IGOR
IPC: A61K31/535
Filed: 2015-12-21
Abstract: A compound having the Formula as follows: (F) wherein R, R1 and R2 are selected from hydrogen, aryl, fused aryl, heteroaryl, saturated carbocylclic, partially saturated carbocyclic, saturated heterocyclic, partially saturated heterocyclic, C1-10 alkyl, haloalkyl, alkenyl, alkynyl, arylalkyl, arylalkenyl, arylalkynyl, heteroarylalkyl, heteroarylalkenyl, alkenylalkyl, alkynylalkyl, carbocycloalkyl, heterocycloalkyl, hydroxyalkyl, aminoalkyl, carboxyalkyl, nitroalkyl, cyanoalkyl, acetamidoalkyl, and acyloxyalkyl. A process for the preparation thereof is also provided.
Patent CA-2976763-A1 (CA)
Inventor: HAGER JAMES
IPC: H01J49/26
Filed: 2016-03-22
Abstract: Systems and methods described herein utilize a multipole ion guide that can receive ions from an ion source for transmission to downstream mass analyzers, while preventing unwanted/interfering/contaminating ions from being transmitted into the high-vacuum chambers of mass spectrometer systems. In various aspects, RF and/or DC signals can be provided to auxiliary electrodes interposed within a quadrupole rod set so as to control or manipulate the transmission of ions from the multipole ion guide.
Patent CA-2977906-A1 (CA)
Inventor: BALOG JULIA
IPC: A61B10/04
Filed: 2016-03-07
Abstract: An apparatus is disclosed including a tool comprising a first device (21) for generating aerosol (5) from a target (35), the first device (21) being deployed through an opening (37) in a tubing (22) of the tool,wherein the tubing (22) is provided with aspiration ports or fenestrations (30) such that the generated aerosol (5) is aspirated into the tubing (22) via the aspiration ports or fenestrations (30). The aspirated aerosol (5) is then transferred to a mass spectrometer for subsequent mass analysis.
Patent CA-2978601-A1 (CA)
Inventor: GOUTHEZ MARION
IPC: A61B5/00
Filed: 2016-03-04
Abstract: L'invention concerne un dispositif de suivi (1) de la respiration d'un utilisateur comprenant: - un support textile (2) comprenant une partie tubulaire(21) formée par tricotage d'un fil de fond majoritaire électriquement isolant, la partie tubulaire (21) étant propre à revêtir le buste de l'utilisateur, - au moins un capteur de respiration (3, 4) formé par tricotage d'un fil de détection (17), le fil de détection (17) comprenant une âme interne en matériau électriquement isolant et une gaine externe entourant l'âme interne, la gaine externe étant formée en matériau électriquement conducteur, dans lequel le capteur de respiration (3, 4) forme une bande conductrice (31, 41) présentant une première extrémité (311, 411) et une deuxième extrémité (312, 412) positionnées à distance l'une de l'autre, les extrémités étant propres à être raccordées à un appareil pour mesurer la résistance électrique de la bande conductrice (31, 41).
Patent CA-2981068-A1 (CA)
Title: Therapy for malignant disease comprising the inhibition of human epididymal secretory protein e4 and immune checkpoint inhibitors
Inventor: MOORE RICHARD G
IPC: A61K31/704
Filed: 2016-03-28
Abstract: Provided herein, inter alia, are methods and compositions directed to suppressing tumor cell growth in a subject as well as methods for sensitizing a proliferating cell for treatment with a cytotoxic agent via inhibiting expression of HE4 and one or more immune checkpoint inhibitors (ICIs). Also provided herein are methods for determining whether a subject who has been diagnosed with cancer would benefit from immunotherapy as well as methods for determining whether a subject with cancer is responding to immunotherapy via assessment of levels of HE4 gene and/or protein expression.
Patent CA-2981639-A1 (CA)
Inventor: BARDOT CHRISTOPHE
IPC: B62D5/065
Filed: 2016-11-09
Abstract: The invention relates to a power steering electrohydraulic system (100) for an electric vehicle, comprising: - at least one reservoir (102) of hydraulic fluid, and - at least one hydraulic actuator (104) for actuating a steering rack shaft (106) of the said vehicle; - at least two electric motor pump units (1081-1082) in parallel for supplying the said actuator (104) with hydraulic fluid from the said reservoir (102) and adjusting the flow rate of the hydraulic fluid supplied to the said actuator (104), characterized in that each electric motor pump unit (1081-1082) is a motor pump unit operating at a voltage of 24V. It also relates to a vehicle equipped with such a system.
Patent CA-2983132-A1 (CA)
Title: Airfoil with dual-wall cooling for a gas turbine engine
Inventor: RHODES JEFFREY F
IPC: F01D25/12
Filed: 2017-10-20
Abstract: An airfoil with dual wall cooling for a gas turbine engine comprises a spar having pressure and suction side walls that meet at leading and trailing edges of the airfoil, with a tip extending therebetween.  An interior of the spar includes a coolant cavity, and each of the pressure and suction side walls includes an arrangement of pedestals on an outer surface thereof and a plurality of cooling holes in fluid communication with the coolant cavity. A pressure side coversheet overlies the pressure side wall and terminates in a radial direction short of the tip of the spar to form a shelf extending along a chordal direction. Flow channels between the pressure side wall and coversheet are configured to direct coolant from the cooling holes to radial flow outlets adjacent to the shelf. A suction side coversheet overlies the suction side wall, and a coolant circuit between the suction side wall and coversheet does not include radial coolant outlets.
Patent CA-2984467-A1 (CA)
Inventor: APONTE LUIS JUAN
IPC: E06B7/30
Filed: 2016-04-01
Abstract: The invention relates to a domestic security system installed in an enclosure, window or door, said system comprising a sensor (3) used to detect controlled magnetic fields and connected to an antenna (4) configured as a single electrode, such that the sensor measures disturbances in the magnetic field around the antenna. The domestic security system is characterised in that the controlled-magnetic-field sensor is configured to detect a disturbance in the magnetic field detected by the antenna and determine if a person is present according to the strength of the disturbance; and to send an alarm indicating the presence of a person.
Patent CA-2985806-A1 (CA)
Inventor: JACOBSON KATHLENE LAURIE
IPC: E21B43/28
Filed: 2016-05-19
Abstract: Injection fluids formed of reverse emulsions and related methods of forming and using reverse emulsions for cavity control in solution mining. The reverse emulsion can reduce the volume of oil required to create an oil pad at the roof of a solution mining cavern in order to prevent vertical leaching and cavern collapse. The reverse emulsion can be formed from an emulsifier, a brine solution and oil. The emulsifier concentration can range from about 1% to about 5% by weight of the reverse emulsion. The emulsifier and the oil can be combined to form an oil/emulsifier mixture, wherein the oil/emulsifier mixture is combined with the brine solution to form the reverse emulsion. The oil/emulsifier mixture can be from about 1% to about 5% by weight of the reverse emulsion.
Patent CA-2987128-A1 (CA)
Inventor: RAHMEL MARCUS RAINER
IPC: A61J1/14
Filed: 2016-06-14
Abstract: The present invention relates to a container system having at least two containers, preferably bottles, each comprising a removal opening, preferably closed off by a septum in each case, wherein the containers comprise, on a side remote from the respective removal opening, particularly on the bottom of the respective bottle, a connecting arrangements for providing a fluidic connection between the containers, and/or having at least one container which comprises a removal opening, the container comprising, on a side remote from the removal opening, a removable, caplike cover which comprises a holding device, for a region of the container forming the removal opening, so that the cover can be used as a support foot for the container when it is held by the holding device by the region forming the removal opening.
Patent CA-2987136-A1 (CA)
Inventor: MATHEWS ROGER
IPC: H01R4/66
Filed: 2017-11-28
Abstract: A ground block may include a metal ground plate and a ground wire fixedly coupled with the metal ground plate. The ground wire is configured to be non-detachable from the ground block during normal use of the ground block. The ground block may be formed by soldering or brazing the ground wire to the metal ground plate.
Patent CA-2988115-A1 (CA)
Inventor: Wang xi-tao
IPC: C07K16/28
Filed: 2016-06-02
Abstract: Provided herein are diagnostic antibodies that bind to glucocorticoid-induced tumor necrosis factor receptor (GITR). Such antibodies are useful for methods of detecting the expression of GITR in biological samples, for example, tumor tissue, and identifying a cancer patient likely to respond to anti-GITR immunotherapy or predicting whether a cancer patient will respond to anti-GITR immunotherapy.
Patent CA-2988196-A1 (CA)
Inventor: NAKASHIMA HIROSHI
IPC: A61K48/00
Filed: 2016-05-04
Abstract: Les tumeurs malignes qui sont résistantes aux thérapies conventionnelles constituent des défis thérapeutiques considérables. Un mode de réalisation de la présente invention concerne un virus oncolytique de deuxième génération rQNestin34.5v2 ayant une plus faible toxicité et qui est plus efficace pour l'élimination sélective de cellules cibles, telles que des cellules tumorales. Dans différents modes de réalisation de la présente invention, le virus oncolytique de l'invention de la présente invention est adapté pour le traitement d'un glioblastome, ainsi que d'autres cancers.
Patent CA-2989074-A1 (CA)
Inventor: EL-SAYED ASHRAF M
IPC: A01N25/18
Filed: 2016-06-10
Abstract: The invention relates to a composition for attracting Lepidopterous insects comprising a vapour blend of acetic acid and one or more compounds of formula (I), (I) wherein R is selected from the group comprising -CH2OH, -CN, -NC, and -OH; and to methods of using the composition to attract, detect, survey, monitor and/or control Lepidopterous insects.
Patent CA-2989239-A1 (CA)
Title: Procede de fabrication de carbodiimides polymeres avec ajout de sels de cesium, polymeres carbodiimides et leur utilisation
Inventor: LAUFER WILHELM
IPC: C08G18/02
Filed: 2016-06-14
Abstract: La présente invention concerne un procédé de fabrication de carbodiimides polymères avec ajout de sels de césium, et des carbodiimides polymères fabriqués selon ledit procédé, ainsi que leur utilisation en tant qu'agent de protection contre l'hydrolyse, notamment dans des systèmes à base de polyuréthane (PU), de préférence des TPU thermoplastiques, des adhésifs PU, des résines de coulée PU, des élastomères PU ou des mousses PU.
Patent CA-2992342-A1 (CA)
Title: Chamber fed combustor cowl
Inventor: MCCORMICK KEITH ALAN
IPC: F23R3/02
Filed: 2018-01-18
Abstract: A gas turbine engine includes a combustion system. The combustion system may include a combustor positioned in a chamber created by an outer wall. A  compressor, such as a centrifugal compressor may provide a flow of compressed air into the chamber along an inner surface of the outer wall since an inlet for the flow of compressed air is outboard of the combustor. The pressurized flow of air may be redirected by a cowl included in the chamber. The cowl may include a collar defining a notch in the cowl. The collar may redirect the flow of pressurized air so as to minimize a high velocity component of the flow of pressurized air flowing radially toward a central axis of the engine prior to entering a head of a fuel nozzle included in the combustion system.
Patent CA-2992394-A1 (CA)
Title: Methode mise en oeuvre par ordinateur, systeme et produit de programme informatique servant a simuler le comportant d'untissu tricote au niveau du fil
Inventor: CIRIO GABRIEL
IPC: G06F17/13
Filed: 2016-07-15
Abstract: L'invention concerne un procédé mis en oeuvre par ordinateur, un système et un produit programme d'ordinateur pour simuler le comportement d'un textile tissé au niveau du fil. Le procédé consiste à: -récupérer des informations structurales d'un textile tissé; -représenter chaque trame avec quatre nodules (4) de contact à l'extrémité des deux contacts (5) de trame entre paire de boucles (2), chaque nodule (4) de contact étant décrit par une coordonnée (x) de position 3D et deux coordonnées (u, v) de glissement qui représentent les longueurs d'arc des deux fils en contact; -mesurer des forces au niveau de chaque nodule (4) de contact sur la base d'un modèle de force qui comprend des forces d'enroulement pour capturer l'interaction des fils au niveau des trames; -calculer le déplacement de chaque nodule (4) de contact en une pluralité d'étapes de temps à l'aide d'équations de mouvement dérivées à l'aide des équations de Lagrange-Euler, et intégrées numériquement au temps, les équations de mouvement prenant en compte la densité de masse distribuée uniformément le long des fils, ainsi que les forces mesurées et le conditions de contour.
Patent CA-2993849-A1 (CA)
Title: Computer-based retirement planning methods and apparatuses
Inventor: MACDONALD BONNIE-JEANNE
IPC: G06Q40/00
Filed: 2018-02-02
Abstract: There is described a computer implemented method comprising calculating a current living standard cost, calculating potential retirement spending, calculating a difference between the current living standard cost and the potential retirement spending and outputting the difference.
Patent CA-2994710-A1 (CA)
Inventor: MONACO TIMOTHY A
IPC: B65F3/00
Filed: 2018-02-12
Abstract: Le conteneur de déchets à double paroi fournit un conteneur amovible ouvert rectangulaire et ayant des parties de verrouillage de porte à une extrémité. Le conteneur utilise une construction à double paroi pour réduire au minimum les dommages, pour améliorer la force et pour alléger. De plus, le conteneur fournit une pluralité douvertures de drain qui sétendent sur la pleine longueur du conteneur pour permettre aux liquides accumulés de sécouler et pour prévenir que le conteneur se corrode.
Patent CA-2997293-A1 (CA)
Inventor: KUTSCH JOHN
IPC: F01P1/06
Filed: 2016-09-01
Abstract: A pneumatic motor assembly that includes a pneumatic motor, which is driven by a compressed gas. The pneumatic motor assembly has a magnet assembly that magnetically couples the pneumatic motor assembly to an implement. After having being used to drive a pneumatic motor, the gas, which has expanded and become colder, cools the magnet assembly The pneumatic motor assembly can thus enable the use to the implement at temperatures at which the magnet assembly would otherwise reach or exceed the maximum operating temperature of the magnet assembly. A flow induction system that includes the pneumatic motor assembly. A method of operating a pneumatic motor assembly that also cools a magnet assembly that is part of the pneumatic motor assembly.
Patent CA-2998486-A1 (CA)
Inventor: MANAHAN JOSEPH MICHAEL
IPC: F21V31/00
Filed: 2016-09-22
Abstract: A light fixture is disclosed herein. The light fixture can include a base having at least one wall that forms a cavity, where the at least one wall includes at least one lens mating surface. The light fixture can also include a lens having at least one base mating surface that forms a hermetic seal with the at least one lens mating surface, where the hermetic seal encapsulates the cavity. The light fixture can further include at least one solid state light source disposed within the cavity.
Patent CA-2999411-A1 (CA)
Title: Association de glycosaminoglycanes et d'un agent antiacide et compositions associees
Inventor: PIZZONI ANGELO
IPC: A61K33/06
Filed: 2016-09-30
Abstract: La présente invention concerne une association d'acide hyaluronique, du sulfate de chondroïtine en association avec au moins un agent antiacide, en particulier du magaldrate, pour la prévention ou le traitement de l'hyperacidité gastrique et du reflux gastro-sophagien et de leurs pathologies associées. Plus particulièrement, ladite association est utilisée pour la préparation de compositions à administrer par voie orale comprenant au moins un vecteur de médicament et comprenant également avantageusement un agent bioadhésif.
Patent CA-3000306-A1 (CA)
Inventor: SUN HONG
IPC: A61K31/5415
Filed: 2015-09-29
Abstract: The present invention is directed to a method of administering a meloxicam formulation to a mammalian subject in need thereof including: orally administering to the subject an oral solid dosage form including an amorphous meloxicam-cyclodextrin inclusion complex, where administering the amorphous meloxicam-cyclodextrin inclusion complex results in the subject achieving a Tmax not greater than about 3.0 hours.
Patent CA-3000888-A1 (CA)
Inventor: HARPER JOHN R
IPC: A61B17/00
Filed: 2010-07-01
Abstract: Devices (10) and methods for treating an abdominal incision (100) or hernia are described.  An implant for the restoration or prophylactic treatment of an abdominal wall comprises an elongate element (12) and at least one sheet (20a, 20b) connected to the elongate element along a longitudinal axis (14) of the elongate element. The elongate element is positioned along the line of incision, and the at least one sheet is secured to the abdominal muscles (50) surrounding the incision.
Patent CA-3003347-A1 (CA)
Title: Procede ex vivo permettant de tester une sensibilite cellulaire de populations de cellules primaires a un medicament ou a une combinaison de medicaments
Inventor: BALLESTEROS NOBELL JUAN ANTONIO
IPC: C12N5/09
Filed: 2016-11-04
Abstract: La présente invention se rapporte à un procédé permettant de produire un environnement artificiel de populations de cellules primaires, en particulier un environnement tumoral artificiel de populations de cellules tumorales primaires et à son utilisation dans un procédé ex vivo afin de tester la sensibilité cellulaire de populations de cellules tumorales primaires à un médicament ou à des médicaments. Le procédé de l'invention comprend l'incubation des cellules tumorales primaires avec l'environnement tumoral artificiel et le médicament ou les médicaments et l'analyse de la réponse des populations de cellules tumorales primaires. L'incubation des cellules tumorales primaires avec l'environnement tumoral artificiel améliore la viabilité desdites cellules tumorales et/ou induit des niveaux supérieurs de prolifération de cellules tumorales et, par conséquent, augmente la sensibilité et la précision du test en ce qui concerne le médicament dosé ou les médicaments dosés.
Patent CA-3004166-A1 (CA)
Inventor: LANGDON STEPHEN DONALD
IPC: F41B5/12
Filed: 2018-05-04
Abstract: A safety device for a crossbow includes a wrist strap with a crank aperture in a palm portion thereof, and is secured around a user's wrist with the crank aperture over the palm of the user's hand. The crank aperture allows passage therethrough of a shaft of a crossbow crank, but prevents passage of a handle; wearing the wrist strap, the user can grasp the handle with the shaft extending through the crank aperture away from the palm of the user's hand. The wrist strap can be divided at its dorsal- wrist portion and include a closure to allow the wrist strap to be secured around or removed from the user's wrist as desired. Restraint of the crank handle by the crank aperture prevents uncontrolled spinning of the crossbow crank.
Patent CA-3004453-A1 (CA)
Title: Administration de toxine botulinique pour le traitement de l'incontinence urinaire associee a l'hyperactivite neurogene du detrusor
Inventor: HAAG-MOLKENTELLER CORNELIA C
IPC: A61P13/10
Filed: 2016-11-17
Abstract: L'invention concerne des méthodes pour traiter l'incontinence urinaire associée à l'hyperactivité neurogène du détrusor (NDO) et pour réduire le besoin ou la fréquence de cathétérisme intermittent propre (CIP) par injection d'un dérivé clostridial dans la vessie d'un patient.
Patent CA-3005634-A1 (CA)
Title: System and method for treatment of spent caustic wastewater
Inventor: MILOSEVIC VESELIN
IPC: C02F9/08
Filed: 2015-11-19
Abstract: The present disclosure relates to a process for treating and regenerating a spent caustic solution at ambient temperatures and pressure which includes oxidizing spent caustic wastewater with a brine solution and ozone mixture, supported by irradiation of the spent caustic wastewater by ultrasound. A range of wastewater treatment techniques may also be included to reach a desired effluent quality level.
Patent CA-3005826-A1 (CA)
Inventor: GELFAND CRAIG A
IPC: B01L3/00
Filed: 2014-04-14
Abstract: A biological fluid collection device that is adapted to receive a blood sample having a cellular portion and a plasma portion is disclosed. After collecting the blood sample, the biological fluid collection device is able to transfer the blood sample to a point-of-care testing device or a biological fluid separation and testing device. After transferring the blood sample, the biological fluid separation and testing device is able to separate the plasma portion from the cellular portion and analyze the blood sample and obtain test results.