baber/WOPTO huggingface dataset:
Patent SG-11201903786U-A (SG)
Title: Farnesyltransferase inhibitors for use in methods of treating cancer
Inventor: GUALBERTO ANTONIO
IPC: A61K31/00
Filed: 2017-11-02
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 11 May 2018 (11.05.2018) Hu omits I 11°1 00111E1M 101HOHOME MIME (10) International Publication Number WO 2018/085518 A2 WIPO I PCT W O 20 18/0855 18 A2 B FIG. IA-B (51) International Patent Classification: A61K 31/00 (2006.01) (21) International Application Number: PCT/US2017/059686 (22) International Filing Date: 02 November 2017 (02.11.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/417,044 03 November 2016 (03.11.2016) US (71) Applicant: KURA ONCOLOGY, INC. [US/US]; 11119 North Torrey Pines Road, Suite 125, La Jolla, CA 92037 (US). (72) Inventors: GUALBERTO, Antonio; 8 Larch Road, Ac- Published: ton, MA 01720 (US). SCHOLZ, Catherine Rose; 1 Nashua Street, Woburn, MA 01801 (US). (74) Agent: RIEGER, Dale L. et al.; Jones Day, 250 Vesey Street, New York, NY 10281-1047 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). without international search report and to be republished upon receipt of that report (Rule 48.2(g)) = (54) Title: METHODS OF TREATING CANCER PATIENTS WITH FARNESYLTRANSFERASE INHIBITORS (57) : The present invention relates to the field of molecular biology and cancer A biology. Specifically, the present invention relates to methods of treating a subject with a farnesyltransferase inhibitor (FTI) that include determining whether the subject is likely to be responsive to the FTI treatment based on HRAS mutation status in the subject.
Patent IS-1487-B (IS)
Inventor: RASMUSSEN POUL LEHN
IPC: C04B20/10
Filed: 1981-12-17
Abstract: The invention relates to a method of producing a dry cement composition, said method comprising feeding a continuous flow of a starting material (C, G), which includes cement binder clinker (C) and a content of water soluble chromate, to a cement mill (19 - 21), grinding the starting material in the cement mill while introducing a cooling medium into the mill so as to maintain the temperature of the material in the mill at a desired level, continuously discharging the ground cement material from the cement mill, and transferring the ground cement material to a storage container (33), characterized in that ferrous sulfate (FeSO4.nH2O) in an amount of 0.01 - 10 percent by weight is added to and mixed with said flow of material in a dry or non-dissolved condition at a location or at locations upstream of said storage container (33) in order to eliminate or substantially reduce said content of water-soluble chromate. Furthermore, the invention relates to a plant for carrying out the aforementioned method.
Patent IT-1050003-B (IT)
Title: Automatic fuse making machine with five work stations - has work stations arranged around rotating tables for assembling fuse components
IPC: H01C/
Filed: 1975-12-05
Granted: 1981-03-10
Abstract: The automatic fuse-making machine, for fuses consisting of fuse wire enclosed in a tube between two end caps, has two parallel-rotating discs with holes in their circumferences and stopping in sequence opposite five work stations. The first station feeds the tubes into the holes in the first disc. The second station inserts the fuse wire into the tubes. the third station adds the end caps and bends the end of the fuse wire round so that it is held between tube and cap. Tin solder is inserted at this station. the fourth station melts the solder. The fifth station cools the solder.
Patent YU-45585-B (YU)
Title: Vezje za krmiljenje glazbenih instrumentov s svetlobnim snopom
Inventor: FRANK MENO
IPC: G05B11/36
Filed: 1984-01-09
Abstract: VEZJE ZA KRMILJENJE GLAZBENIH INSTRUMENTOV S SVETLOBNIM SNOPOM, priključeno na modulator napetostno krmiljenje amplitude 20, na katerega je priključen frekvenčni generator 22 in pri katerem je izhod modulatorja 20 doveden v mikser 24 in v njem kombiniran z drugimi, na enak način krmiljenimi signali 25 ter so ti signali prek izhodne kontrole 26 dovedeni do zvočnika 28, označeno s tem, da je svetlobni izvor (10, 41, 58, 75, 80) nameščen nasproti ali ob detektorju (14, 42, 60, 77, 82), katerega izhod je povezan z vhodom ojačevalnika (16), izhod tega ojačevalnika (16) pa z vhodom diferencialnega ojačevalnika (18), katerega izhod je povezan z vhodom modulatorja (20).
Patent AT-392604-B (AT)
IPC: B24D3/12
Filed: 1989-01-30
Granted: 1991-05-10
Abstract: In a process for the production of abrasive bodies having particulate abrasive material, such as, for example, SiC, corundum, Al2O3 or B4C, bound in a binder, plastic and MgO and MgCl2 being used as binders, the plastic employed is a polycarboxylic acid. The moulded abrasive bodies are bound or hardened without heating, by reacting the polycarboxylic acids with magnesium ions.
Patent AT-404421-B (AT)
Title: Plant for pasteurizing liquids
Inventor: PRUGNER SIEGFRIED
IPC: A23C3/03
Filed: 1996-02-20
Granted: 1998-11-25
Abstract: Plant for pasteurizing liquids, comprising a raw liquid vessel 1, a vessel 2 for receiving the pasteurized liquid, a liquid heater 3 and a device 4 for transporting the raw liquid from the raw liquid vessel 1 through the heater 3 into the pasteurized liquid vessel 2, the liquid heater 3 having a controller for keeping the liquid temperature constant at the heater outlet 31 and a device being provided for automatically changing the liquid flow rate through the heater 3 as a function of the flow rate of the liquid taken off from the pasteurized liquid vessel 2 and the device for changing the liquid flow rate being formed by at least one valve 6 which is disposed in the raw liquid feed line and can be actuated in dependence on a level sensor disposed in the pasteurized liquid vessel 2. <IMAGE>
Patent AT-399656-B (AT)
Title: Process for the production of cancer vaccines
Inventor: ZATLOUKAL KURT DR
IPC: C12N15/87
Filed: 1993-03-19
Granted: 1995-06-26
Abstract: Cancer vaccines are obtained by treating tumour cells or fibroblasts with a complex of DNA coding for an immunostimulating polypeptide, and of a DNA-binding substance, e.g. polylysine, which is preferably conjugated with transferrin. The complex also contains a conjugate of DNA-binding substance and an adenovirus. The adenovirus has at least one E4 defect or one E1a defect in combination with other gene defects.
Patent HU-195527-B (HU)
Inventor: BERAN MIROSLAV
IPC: C08L27/06
Filed: 1986-01-10
Abstract: A találmány tárgya lágyítóval készített PVC-paszta, amelyből makroporózus lapszerű termékek; illetve térbeli formatestek állíthatók elő. A találmány szerinti PVC pasztára jellemző, hogy össztömegére számítva 10—60 tömeg % mennyiségben olyan szuszpendált hidrofil rendszert tartalmaz, amely —   folyékony fázisként mérsékelten illékony, vízben oldódó, ftálsavészter típusú lágyítókkal korlátozott mértékben elegyedő, hidrofil folyadékot, mégpedig etilén-glikolt, dietilén-glikolt, trietilén- *:   glikolt, propilénglikolt, polietilén-glikolt, dipropi- lén-glikolt, tripropilén-glikolt, glicerolt, trimetilolpropánt, etanolamint, dietanolamint, trietanolamint, formamidot vagy a felsoroltak bármilyen elegyét vagy karbamid, illetve acetamid valamely fenti oldószerrel készített oldatát és —   a fenti folyadék(ok)ban 40—160 °C-on duzzasztott polimer hidrofil anyagot, például natív vagy kémiailag módosított keményítőt tartalmaz 1:3 és 3 :1 közötti arányban. A pasztából kenési eljárással kialakított lapszerű terméket forró vízben mossák, a hidrofil rendszer kioldódása érdekében. A műbőrként alkalmazható anyag vízgőzáteresztő képessége kiváló. -1-
Patent HU-190363-B (HU)
Inventor: MIESEL JOHN L
IPC: C07D213/89
Filed: 1981-01-22
Abstract: Verfahren zur Herstellung von 2,6-Dihalogenbenzoylderivaten der Formel I, worin R und R hoch 1 Chlor oder Fluor bedeuten und R hoch 2 fuer Chlor, Brom oder Trifluormethyl steht durch Umsetzung eines entsprechend substituierten 2,6-Dihalogenbenzoylisocyanats mit einem 2-Aminopyridin oder eines 2,6-Dihalogenbenzamids mit einem 2-Pyridylisocyanat oder eines reaktionsfaehigen Derivats einer 2,6-Dihalogenbenzamidocarbonsaeure mit einem entsprechenden Aminopyridin oder eines Benzamids mit einem aktiven Derivat einer Pyridinylaminocarbonsaeure, Verwendung dieser Derivate zur Bekaempfung von im Mist aufwachsenden Insekten, indem man warmbluetigen Tieren eine solche Menge der Derivate verdauen laesst, dass ihre Faekalien eine insektizid wirksame Menge enthalten.
Patent HU-202017-B (HU)
Title: Method for reutilizing dry cells, mounted printed circuits and electronic details
Inventor: HANULIK JOZEF
IPC: H01M6/52
Filed: 1987-12-03
Abstract: For the recycling of electrical batteries, in particular of a mixture of high-power batteries for equipment of any chemical composition, and also of assembled printed circuit boards and electronic components, a pyrolysis of the unsorted mixture is carried out at a temperature between 450 DEG  and 650 DEG , then an electrolysis of the pyrolysis slag is carried out and subsequently a separation of the electrolysis products and removal of the products accumulating at the electrodes is carried out. In this process, which is economically profitable, no environment-polluting residues are produced and an initial sorting of material becomes unnecessary.
Patent HU-192978-B (HU)
Inventor: SASDI ANDRAS
IPC: G01N23/04
Filed: 1984-02-20
Abstract: A találmány radiográfiai felvételek kiértékelésére szolgáló videodenzitométer. A berendezésben a megvilágító szerkezet (1) és a TV-kamera (3) között helyezhető el a radiogram (2). A TV-kamera (3) videojel kimetete (5) soros összegzőkén (15, 16, 17, 18) keresztül TV-monitor (19) és/vagy jelrögzitó (2) bemenetére csatlakozik. A TV-kamera (3) soreltéritőjel kimenete (4) párhuzamos komparátorok (10, 11, 12) jelbemeneteire kapcsolódik. A soreltéritőjel kimenet (4) ezenkívül szinkron jelleválasztó egységen (6) és eltoló-forgatójel generátoron (7) keresztül az első komparátor (10) komparáló jel bemenetére van kötve, amelynek kimenete egy kapcsolón (21) keresztül az első összegző (15) másik bemenetére csatlakozik. A második és harmadik komparátor (11, 12) komparálójel bemenetelre egy-egy markerjel generátor (13,   14) van kötve, s a komparátorok (11, 12) kimenetei egy-egy kapcsolón (22, 23) a második és harmadik összegzővel (16,17) vannak összekötve, A negyedik összegző (18) ugyancsak egy kapcsolón (24) keresztül a videojelkimenetről (5) táplált és az első komparátor (10) kimenetéről vezérelt mintavevő egység (8) jelkimenetére csatlakozik.  192978 -1-
Patent LT-4239-B (LT)
Title: Device for thermal packing of articles
Inventor: GAILIUS ARVYDAS
IPC: B65B9/06
Filed: 1995-12-01
Abstract: The invention applies to packing engineering. The device consists of a stand (1), thermal chamber (2), where there is, an air mixing fan (3) and heating device installed. The heating device consists of 8-10 mm diameter heating spirals made of wolfram or a nichrome wire, the diameter of which is 1.8-2.0 mm (4) and insulators (5) installed in cuttings. Above the thermal chamber (2) there is a cooling fan mounted (6). There is a belt conveyer (7) for product conveying in and out of the thermal chamber (2). The conveyer's belt is held by rollers. The conveyer (7) gets its motion from an electric engine (9) through a belt drive (10).
Patent YU-49266-B (YU)
Inventor: METCALF C STEPHEN
IPC: B26B21/40
Filed: 1998-02-18
Abstract: Spremnik za kasete (10) sa kasetama za nožić za brijanje (12) uključujući kućište koje definiše odeljak za prihvatanje kasete koja ostaje u ovom odeljku u predodređenom položaju, koji omogućava priključivanje pomenute kasete (12) na priključnu strukturu drške (64) navedene drške (63), naznačen time, što se ista priključna struktura drške (64) povezuje sa navedenom kasetom (12) kada se navedena drška (63) kreće prema navedenoj kaseti (12), i što se zapor (22) nalazi u kućištu i ima bregastu strukturu zapora (54) i što se zadržavajući deo kasete prostire sa prihvatnim delom kasete kućišta, a navedena bregasta struktura zapora (54) je oblikovana i postavljena da sadejstvuje sa odgovarajućom strukturom drške tako da izazove savijanje zapora (22) u slobodan položaj u kome navedeni zadržavajući deo kasete oslobađa navedenu kasetu (12), kada se navedena drška (63) kreće prema priključnoj strukturi navedene kasete (12) i spaja sa njom. Prijava sadrži još tri nezavisna i trideset osam zavisnih patentnih zahteva.
Patent ZA-83165-B (ZA)
Title: Stencil printing machine
Inventor: SVANTESSON AKE
IPC: B41F15/08
Filed: 1983-01-11
Abstract: Stencil printing machine including printing table (1), a number of movably arranged material gripping and displacement arrangements (2, 3) a stencil (5) tensioned in a frame (4) and located above the printing table and doctor blade arrangement which can interact with the stencil. At least one material gripping and displacement arrangement (2) has imparted to it a reciprocating motion between two predetermined positions. One position (fig. 1) for gripping and fetching material (A) intended for printing and a second position (fig. 2) for placing the fetched material on the printing table (1). The position of the arrangement is registered in both the first and the second position.
Patent ZA-88988-B (ZA)
Title: Bituminous composition
IPC: C08F297/04
Filed: 1988-02-12
Abstract: Bituminous composition comprising a bitumen, an elastomeric, optionally hydrogenated, block copolymer containing at least two monoalkenyl arene blocks A and at least one conjugated diene block B which composition further comprises a polymer of a monovinylaromatic hydrocarbon of which polymer the number average molecular weight is the range of 1/4 to 2 times the number average molecular weight of the polymeric blocks A.
Patent AT-397973-B (AT)
IPC: E01B3/48
Filed: 1991-12-11
Granted: 1994-08-25
Abstract: The railway track structure has rails (6) arranged in pairs and, arranged transversely to the rails and connected thereto, sleepers (5) which bear with their end sections on a foundation plate (2) via elastic intermediate layers (7). Provided between the sleepers (5) are intermediate bodies (13) which are connected to the foundation plate (2). The intermediate bodies (13) which are made of concrete are designed as factory-finished elements. The cross-sectional contour of the intermediate bodies (13) is trapezoidal. The cheeks adjacent to the end sections of the sleepers (5) converge downwardly. The length of the intermediate bodies (13) is the same as or slightly smaller than the length of the sections of the sleeper (5) which project outwards seen from the rails (6). These intermediate bodies (13) are screwed together with the foundation plate. Elastic wedges (22) lie between the adjacent cheeks of the end sections of the sleepers (5) and the intermediate bodies (13). The intermediate bodies (13) are passed through by a vertical continuous bore, which lies in the central region, for receiving a fastening screw (9) which can be anchored in the foundation plate (2). The direct surrounding region of the vertical bore passing through the intermediate body (13) is sunk in relation to the surface of the intermediate body (13). <IMAGE>
Patent AT-397694-B (AT)
Title: Soot separator for exhaust gases
IPC: F23J15/02
Filed: 1989-12-21
Granted: 1994-06-27
Abstract: Soot separator for exhaust gases, in particular from internal combustion engines, with a housing 17 which is connectable to an exhaust-gas line and in which is arranged an extractable drawer (18), in which a perforated meander-shaped exhaust-gas pipeline (21) is embedded in soot separation material, preferably basaltic or rock wool, copper or aluminium wool. <IMAGE>
Patent AT-389522-B (AT)
Title: Novel soluble and/or fusible polyimides and polamideimides and process for their preparation
Inventor: GREBER GERD DR
IPC: C08G73/10
Filed: 1987-11-16
Granted: 1989-12-27
Abstract: Soluble and/or fusible polyimides or polyamideimides (I) where R is a divalent radical (II), Ar is trivalent or tetravalent aromatic radicals or a mixture of these, X is the amide radical if Ar is trivalent and is the imide radical if Ar is tetravalent, and R1 is divalent aromatic radicals, and a process for their preparation. <IMAGE>
Patent DK-158931-B (DK)
Title: Process for producing a delayed-release oral pharmaceutical preparation which comprises 5- aminosalicylic acid
Inventor: RHODES JOHN
IPC: A61K/
Filed: 1983-03-21
Abstract: A solid dosage form, such as a capsule or tablet, containing a pharmacologically active agent is coated with an anionic polymer, which is insoluble in gastric juice and in intestinal juice below pH7 but soluble in colonic intestinal juice, in a sufficient amount that the oral dosage form remains intact until it reaches the colon. The preferred anionic polymer is a partly methyl esterified methacrylic acid polymer in which the ratio of free carboxylic groups to ester groups is about 1:2. The invention has particular application to dosage forms of prednisolone and salts thereof, indomethacin, ibuprofen, and, especially, 5-amino-salicylic acid.
Patent DK-149155-B (DK)
Inventor: STOSS PETER
IPC: C07D493/04
Filed: 1982-06-21
Abstract: A process for the preparation of isosorbide-2-nitrate of the formula <IMAGE>   comprising contacting isosorbide with a carboxylic acid anhydride in the presence of a metal salt; esterifying the resultant isosorbide-5-acylate with nitric acid; and converting the resultant isosorbide-5-acylate-2-nitrate to isosorbide-2-nitrate by treatment with an alkyl alcohol in the presence of an alkali metal alcoholate.
Patent DK-159062-B (DK)
Inventor: ATZORN HEINZ
IPC: B61D17/20
Filed: 1985-06-28
Abstract: 1. A vehicle, in particular a rail vehicle, having a head portion (1) which comprises a driver's cab (2) located at the level of the passenger space, a door (3) in the front wall and a tunnel-shaped passage (5) which is connected to a transition arrangement (4) and can be transferred into the region of the head part (1) remote from the door (3) in the front wall - first end position - when the vehicle is used as front vehicle, and onto a frame (3a) of the open door (3) in the front wall - second end position - when the vehicle is used as coupled vehicle, characterised in that the door (3) in the front wall has, on the driver's cab side, a driver's console (8a) as a section of a driver's table (8) provided with operating and control devices, this driver's console (8a) lying outside the passage (5) situated in its second end position when the door (3) in the front wall is open toward the driver's cab (2).
Patent FI-78260-B (FI)
Inventor: GRIFFITHS ANTHONY CHARLES MURR
IPC: B29C39/22
Filed: 1982-10-15
Granted: 1989-03-31
Abstract: PCT No. PCT/GB82/00040 Sec. 371 Date Oct. 5, 1982 Sec. 102(e) Date Oct. 5, 1982 PCT Filed Feb. 15, 1982 PCT Pub. No. WO82/02851 PCT Pub. Date Sep. 2, 1982.A method of continuous upwards production of foamed material by feeding foam forming materials from below and taking foamed material away from above, wherein foaming takes place in diverging expansion enclosure (1) the walls (13, 14) of which are provided with surfaces (15, 17) travelling with the foaming material, which enclosure (1) is defined above by foam already expanded, at the sides by said walls (13, 14) and below by a feed zone for the foam forming materials, and leads into an upwardly directed take off path for the foam.
Patent FI-84271-B (FI)
Inventor: CHILD RALPH GRASSING
IPC: C07F15/00
Filed: 1987-01-30
Granted: 1991-07-31
Abstract: Organic platinum complexes active as anti-tumor agents in warm-blooded animals, and methods for synthesis of same, are described.
Patent FI-86932-B (FI)
Inventor: SCHEINERT STEFAN DIPL ING
IPC: H04Q7/18
Filed: 1988-07-07
Granted: 1992-07-15
Abstract: In known paging receivers, which operate in the time-slot method, the supply voltage for the receiving section is switched on and off by a timing section to save energy. The off time is dimensioned in such a manner that the receiving section is fully operative again at the beginning of the next allocated time slot, a fixed-length pause being maintained in each case between the allocated time slots. It is attempted to achieve an energy saving even when the allocated time slots follow one another directly without pause. By immediately comparing the received data with the data which can be predetermined by means of a reference register, a decision is made by a comparator even during the reception of a data block on whether the data which can still be received up to the end of the time slot are significant for the evaluation of the overall data. One field of application of this invention is the portable version of a car telephone. <IMAGE>
Patent FI-95971-B (FI)
Inventor: BLAND PATRICK MAURICE
IPC: G06F13/36
Filed: 1989-04-14
Granted: 1995-12-29
Abstract: A computer system includes a page memory in which a row address accompanied by a row address strobe (RAS) is followed by a column address accompanied by a column address strobe (CAS) to read data from a memory location during a memory cycle. When, in a following memory cycle, a further location from the same page is to be accessed, the row address and the RAS remain constant and a new column address is used with the CAS being precharged by switching it to its OFF state and then returning it to its ON state. This is normally done at the start of the following memory cycle. In the present system, the data is read and latched shortly after arrival of the column address and CAS in the first of the memory cycles so that the CAS recharge can take place at the end of the first memory cycle and before the start of the following memory cycle.
Patent FI-91660-B (FI)
Inventor: LINGEMANN HORST
IPC: E06B3/67
Filed: 1989-09-27
Granted: 1994-04-15
Abstract: The invention relates to a heatable multiple insulating glazing made of at least two glass panes (1, 2) which are held at a distance by a spacer (6), with a gas-filled or evacuated intermediate space (3) and a resistance-heating element (5) on a glass-pane surface (4) on the side of the intermediate space and connections for the supply of an electric current to the resistance-heating element, the spacer (6) consisting preferably of two hollow metal sections, which are arranged parallel next to and at a distance from one another, preferably of hollow aluminium sections, with side walls which are parallel to the glass-pane surfaces, and the intermediate space between the two hollow sections being filled with a plastic which adheres firmly to the surface of the side walls of the hollow sections. The invention also relates to a spacer (6), in particular for the making of a heatable multiple insulating glazing. 
<IMAGE>