baber/WOPTO huggingface dataset:
Patent EP-3805257-A1 (EP)
Inventor: ZHAO LIANGLIANG
IPC: C07K14/62
Filed: 2019-05-23
Abstract: Disclosed is a method for preparing a precursor of a recombinant human insulin or an analogue thereof, comprising: a. bacterial fermentation, centrifuging a fermentation broth in a continuous flow to collect a supernatant; b. filtering the supernatant in step (a) by means of a hollow fiber membrane and collecting the filtrate; and c. purifying the filtrate in the step (b) by means of a chromatography column. The method has the advantages of streamlined steps, scalability, no use of organic solvents, high yield, etc. The purity of the insulin precursor can exceed 90%, the host cell protein removal rate exceeds 90%, and the exogenous DNA removal rate is 89% or greater, achieving less than 0.1 ng/mg.
Patent EP-3815931-A1 (EP)
Inventor: HONDA KYOHEI
IPC: B60C23/04
Filed: 2019-05-21
Abstract: A tire mounting position detection system measures a first signal strength which is the strength of a radio signal received by a first receiver (R1) for each transmitter, measures a second signal strength which is the strength of the radio signal received by a second receiver (R2) for each transmitter, and calculates an strength ratio which is a ratio using the first signal strength and the second signal strength for each transmitter. The tire mounting position detection system detects a wheel position where a tire equipped with a transmitter is mounted on the basis of the first signal strength, the second signal strength and a strength ratio for each transmitter.
Patent EP-3818148-A1 (EP)
Inventor: SPENCER HAROLD TRENT
IPC: C12N5/078
Filed: 2019-07-05
Abstract: Provided herein are recombinant AAV (rAAV) serotypes that are useful for targeting innate immune cells. In some embodiments, the rAAV are used to deliver genes encoding one or more receptors that can target the innate immune cells to diseased tissue of interest. In some aspects, the rAAV particle is a rAAV particle having a mutation in a surface-exposed amino acid, such as tyrosine, threonine, or serine, that enhances transduction of dendritic cells.
Patent EP-3786579-A1 (EP)
Inventor: KOZUMA MIKIO
IPC: G01C23/00
Filed: 2019-06-04
Abstract: A change in geoid height is measured easily. A geoid measurement method of the present invention executes an inertial measurement data acquiring step, a comparison data acquiring step, a state variable estimating step, and a geoid calculating step. In the inertial measurement data acquiring step, data related to velocity, position, and attitude angle is acquired as inertially-derived data based on the output of an inertial measurement part having a three-axis gyro and a three-axis accelerometer attached to a moving body. In the comparison data acquiring step, data related to velocity is acquired as comparison data from a source other than the inertial measurement part. In the state variable estimating step, state variables including a plumb line deviation are estimated by using the inertially-derived data and the comparison data to apply a Kalman filter in which the plumb line deviation is included in the state variables. In the geoid calculating step, a change in geoid height is calculated based on the estimated plumb line deviation at an estimated position that the estimating applied to.
Patent EP-3829508-A1 (EP)
Inventor: MCLELAN LUCAS
IPC: A61F13/40
Filed: 2019-07-30
Abstract: Disclosed herein are various needle penetration preparation devices and methods in which each of the devices have a skin marking mechanism at one end of the device body, a sterilization applicator at another end of the device body, and a compromisable sterilization solution reservoir adjacent to the sterilization applicator.
Patent EP-3833414-A1 (EP)
Inventor: CHOWERS ITAY
IPC: A61M5/20
Filed: 2019-08-05
Abstract: There is provided herein a multi-lumen syringe for intraocular injection, including a first lumen, a second lumen, one or more needles fluidly connected to the lumens, and a needle sheath disposed about the one or more needles; wherein the needle sheath includes a plurality of n proximity/contact/pressure actuators on a distal rim of the needle sheath; wherein the syringe is switchable between at least two configurations: a first configuration in which at least one of the actuators is not actuated and each tip of the one or more needles is proximally positioned, and secured, relative to the distal rim; and a second configuration in which the n actuators are actuated, and the one or more needles are allowed to distally extend beyond the distal rim.
Patent EP-3817269-A1 (EP)
Inventor: CHEN LEI
IPC: H04L5/00
Filed: 2019-08-02
Abstract: This application provides a resource management method and apparatus. A terminal determines at least one reference signal resource corresponding to each of at least two frequency domain resources, and selects at least two reference signal resources from a plurality of reference signal resources corresponding to the at least two frequency domain resources, where the at least two selected reference signal resources are reference signal resources corresponding to at least two different frequency domain resources. In other words, some of the at least two reference signal resources are selected from a plurality of reference signal resources corresponding to one frequency domain resource, and other reference signal resources are selected from a plurality of reference signal resources corresponding to another frequency domain resource. In this way, the terminal can simultaneously receive data sent by a network device by using reference signal resources corresponding to different frequency domain resources, thereby improving communication efficiency.
Patent EP-3838474-A1 (EP)
Inventor: TAKADA ATSUSHI
IPC: B23K35/30
Filed: 2019-04-01
Abstract: Provided is a solid wire for gas metal arc welding, which has a small amount of fume during welding and is suitable as a welding material for high Mn steel materials. The wire has a chemical composition containing, in mass%, C: 0.2% to 0.8%, Si: 0.15% to 0.90%, Mn: 17.0% to 28.0%, P: 0.03% or less, S: 0.03% or less, Ni: 0.01% to 10.00%, Cr: 0.4% to 4.0%, Mo: 0.01% to 3.50%, B: less than 0.0010%, and N: 0.12% or less, with the balance consisting of Fe and inevitable impurities. It may contain at least one selected from V, Ti, Nb, Cu, Al, Ca and REM, if necessary. The wire has excellent manufacturability, can significantly suppress the amount of fume generated during gas metal arc welding, and can easily manufacture a weld joint having high strength and excellent impact toughness at cryogenic tem peratures.
Patent EP-3846889-A1 (EP)
Title: Support pour un appareil et/ou des accessoires d'assistance respiratoire
Inventor: SALMON ANDREW PAUL MAXWELL
IPC: A61M16/06
Filed: 2019-08-28
Abstract: L'invention concerne un appareil support 200 pour une assistance respiratoire 10, présentant une base 203, un support 351 et une poignée 309. Le support 351 est conçu pour accoupler de manière amovible l'appareil support 200 à un appareil d'assistance respiratoire 10 par abaissement de l'appareil d'assistance respiratoire 10 par rapport au support 351. La poignée 309 est conçue pour permettre à l'appareil support 200 et à un appareil d'assistance respiratoire 10 accouplé de manière amovible d'être soulevés et portés par un utilisateur.
Patent EP-3846807-A1 (EP)
Inventor: YANG LIHU
IPC: A61K31/4375
Filed: 2019-09-05
Abstract: Provided herein are imidazoquinoline derivatives, or pharmaceutically acceptable salts thereof, that are agonists of toll-like receptors 7 and 8 (TLR7/8). Also provided herein are compositions and pharmaceutical compositions comprising the imidazoquinoline derivatives, or pharmaceutically acceptable salts thereof, provided herein. Also provided herein are methods of use of the imidazoquinoline derivatives, or pharmaceutically acceptable salts thereof, provided herein to treat various diseases, such as viral, cancer, and allergic diseases, in a subject in need thereof by administering a therapeutically effective amount of the imidazoquinoline derivative, or pharmaceutically acceptable salt thereof, to the subject.
Patent EP-3848227-A1 (EP)
Inventor: OURA YUTA
IPC: B60L9/30
Filed: 2019-03-07
Abstract: When there is a restriction in an outfitting space, a mounted engine generator unit requires an operation restriction such as, for example, the current restriction of a generator if a sufficient heat capacity is not ensured. Therefore, this drive control device is provided with: a power conversion circuit for converting the AC power generated by the generator driven by an engine to a DC power; and a control unit for controlling the switching operation of the power conversion circuit on the basis of a switching operation mode. The control unit changes the switching operation mode in accordance with the rotational speed of the generator driven by the engine, thereby reducing and furthermore minimizing the percentage of the harmonic components of AC current for driving the generator.
Patent EP-3852711-A1 (EP)
Inventor: GURTNER GEOFFREY C
IPC: A61K8/02
Filed: 2019-09-20
Abstract: Provided herein are iron chelating compounds, compositions containing such compounds and methods of using the compounds in treating various aesthetic skin conditions. The iron chelating compositions may be administered topically or orally. Treating the aesthetic skin conditions includes preventing onset or delaying progression of the aesthetic skin condition.
Patent EP-3853036-A1 (EP)
Inventor: HARRIS DAVID BRADLEY
IPC: B43K5/00
Filed: 2019-09-20
Abstract: The instant disclosure is directed to a heterogeneous fiber fluid reservoir for holding and delivering fluid. A reservoir may comprise a rod having a core component and a surrounding component. Each of the core component and the surrounding component may comprise fibers. The core component may have a first property, and the surrounding component may have a second property different from the first property, or the core component and the surrounding component may each have a different value or range of values for the same property. Alternatively, a reservoir may comprise a rod that includes fibers and has a cross-sectional diameter. At least one property of the rod may vary in value along the cross-sectional diameter of the rod. The property may include, for example, fiber bulk density, fiber diameter, fiber material, fiber morphology, fiber surface tension, capillary force, fluid absorption capacity, color, or combinations thereof.
Patent EP-3890682-A1 (EP)
Inventor: MENTINK LÉON
IPC: A61K8/34
Filed: 2019-12-04
Abstract: The present invention relates to a sensory emulsifying composition, in particular for cosmetic use, capable of making it possible to obtain an oil-in-water-type emulsion, comprising at least one cyclodextrin in the form of solid particles, said particles having a volume-average size d(4,3), measured by laser granulometry, of between 2 and 20 μm, preferably between 3 and 12 μm, and more preferably between 4 and 8 μm; and at least one emulsifier of natural origin selected from oil-in-water emulsifiers, having an HLB greater than or equal to 8, and most preferably greater than or equal to 9.
Patent EP-3860596-A1 (EP)
Inventor: ABHARI RAMIN
IPC: A61K31/713
Filed: 2019-10-02
Abstract: La présente technologie concerne des carburants hydrocarbonés comprenant un contenu renouvelable. Plus particulièrement, la technologie concerne la fabrication de diesel renouvelable pour une utilisation potentielle en tant que mélange de carburants de turbine d'aviation.
Patent EP-3860567-A1 (EP)
Inventor: JAGANNATHAN BHARADWAJ
IPC: A61K47/00
Filed: 2019-09-27
Abstract: The invention disclosed herein relates to methods for reducing aggregation of bispecific antibodies, for example reducing aggregation of bispecific T cell engager (BiTE) antibody constructs, resulting from storage under frozen conditions by holding the antibodies at certain temperatures after thaw.
Patent EP-3876925-A1 (EP)
Inventor: DELY AARON MICHAEL
IPC: A61K31/352
Filed: 2019-11-07
Abstract: L'invention concerne des compositions pour administration sublinguale et/ou buccale comprenant au moins un cannabinoïde ou un extrait cannabinoïde, un triglycéride, un alcool et au moins un tensioactif.
Patent EP-3881753-A1 (EP)
Title: Vorrichtung zur erzeugung eines elektromagnetischen feldes und messung der absorption davon durch ein leitfähiges medium
Inventor: KOVALKOV VALERYI KONSTANTINOVICH
IPC: A61B5/00
Filed: 2019-11-15
Abstract: Die Erfindung bezieht sich auf die Diagnostik biologischer Gewebe, Organe und des Organismus insgesamt und basiert auf der Möglichkeit, die Absorption eines niederfrequenten elektromagnetischen Feldes durch verschiedene Medien im Nahbereich zu messen. Die Vorrichtung zum Erzeugen eines elektromagnetischen Felds und zum Messen seiner Absorption durch ein leitendes Medium enthält untereinander verbundene einen Wechselspannungsgenerator, einen Sender (Strahler) des elektromagnetischen Felds und Mittel zum Messen der Absorption des elektromagnetischen Feldes. Dabei wird ein Sender verwendet, der ein torodiales elektromagnetisches Feld erzeugt. Er enthält runde Platten, die in einer Ebene so angeordnet sind, dass eine Platte mindestens ein Loch (eine Öffnung) aufweist, wo mindestens eine andere Platte angeordnet ist. Wobei ist die Platte mit dem Loch von den anderen Platten elektrisch isoliert und das erzeugte elektromagnetische Feld ist in einer Ebene symmetrisch.
Patent EP-3886955-A1 (EP)
Inventor: SHANTHA TOTADA R
IPC: A61M16/00
Filed: 2019-11-27
Abstract: A lower jaw and tongue thrusting endotracheal tube and flexible fiberoptic endoscope intubation oral airway device having an elongated body including, a mandible flange with a lingual flat portion transversely disposed on a ventral surface of a tongue plate. The device having an open top toward the palate like a rectangular trough. The trough extends through the device from the proximal end to the front middle part of the tongue plate. The device includes an L-shaped insert that slideably couples between the upper lip flanges and acts also as dorsal surface of the bite block. The distal end of the tongue plate end comprises a curved surface which tapers to a narrow distal edge. A pair of upstanding walls attach to the tongue faceplate ventral surface edges which taper as they extend posteriorly. The walls ensure protection for medical instruments disposed within the flexible fiberoptic endoscope guide.
Patent EP-3903858-A1 (EP)
Inventor: SUZUKI TAKAMASA
IPC: A61M5/20
Filed: 2019-12-27
Abstract: A needleless injector according to the present disclosure includes a housing part including an accommodating space in which an intended injection substance is accommodated. The housing part includes: 
a housing part main body incorporating the accommodating space; a protrusion that protrudes in an axial direction of the housing part on a distal end side of the housing part, the protrusion including a distal end surface in which the ejection port is formed, the protrusion having an outer diameter that is smaller than an outer diameter of the housing part main body, the distal end surface having at least a part defined by a first straight line and the protrusion having at least a part of a side surface defined by a second straight line in a cross section taken along the axial direction of the housing part, the distal end surface having an outer circumference edge represented by an intersection point between the first straight line and the second straight line; and a connection part connecting the protrusion and the housing part main body to each other, and having an outer surface forming an annular inclined surface that is inclined with respect to a center axis of the housing part and continues from an end portion of the protrusion to an end portion of the housing part main body. With this configuration, a suitable contact state between the ejection port and the target region can be achieved, and high operability of the needleless injector can be maintained.
Patent EP-3903579-A1 (EP)
Inventor: JU JI HYEON
IPC: C12N5/071
Filed: 2019-12-27
Abstract: The present invention relates to a production method of a systemic sclerosis disease model using keratinocytes and fibroblasts differentiated from induced pluripotent stem cells derived from patients with systemic sclerosis, a systemic sclerosis disease model produced thereby, and a method for screening a therapeutic agent for systemic sclerosis using the same.The systemic sclerosis disease model produced by the above production method can be effectively used for preventing or treating systemic sclerosis.
Patent EP-3922384-A1 (EP)
Inventor: HATANO TOSHIAKI
IPC: B23B49/00
Filed: 2019-11-21
Abstract: A work machine unit includes: a support member assembled to an end effector connection part of an operating machine; a work machine part assembled to one end of the support member; and a linear guide disposed at another end of the support member across its connection to the end effector connection part from the support member, arranged in parallel to an axial direction of the work machine part, and configured to abut against a work object or its peripheral structural object. Further, the linear guide is passed through a through-hole formed in the support member, and the support member is configured to move in the axial direction of the work machine part as guided by the linear guide.
Patent EP-3937598-A1 (EP)
Inventor: KUBOTA TOMOKATSU
IPC: G01N21/956
Filed: 2019-03-05
Abstract: A correction amount calculation device includes, in a board work line including a component mounting machine, a reflow furnace, and an appearance inspection machine, a selection section and a correction amount calculation section. The component mounting machine is configured to perform a mounting process of mounting a component on a board on which solder is printed. The reflow furnace is configured to heat the board on which the component is mounted and melt the solder to perform soldering. The appearance inspection machine is configured to inspect a mounting position of the component, which is subjected to the soldering. The selection section is configured to select a target component in which a movement amount of the component on the board before and after being conveyed to the reflow furnace is equal to or less than a predetermined allowable value. The correction amount calculation section is configured to calculate a correction amount, which is used in the mounting process of a board product to be produced later, regarding a positional deviation amount of the mounting position of the target component selected by the selection section with respect to a target mounting position.
Patent EP-3819557-A1 (EP)
Inventor: MENG QINGLIANG
IPC: F25B41/00
Filed: 2019-06-14
Abstract: A refrigeration system, comprising an evaporator (1), a condenser (2), a throttling device (3), a compressor (4), an economizer (5) and an ejector (6), these devices together constituting a closed-loop refrigerant circulation loop, the ejector (6) being connected to the economizer (5), and the ejector (6) being provided on an exhaust side of the compressor (4). The structure enables the refrigeration system to realize the dual-stage boost, does not affect the stability of the compressor (4) due to the instability of the airflow of the ejector (6), and does not affect the oil property of the compressor (4), thereby ensuring the operation safety of the compressor (4).
Patent EP-3955976-A1 (EP)
Inventor: LINDNER TORSTEN
IPC: A61F13/512
Filed: 2019-04-17
Abstract: An absorbent article (20) such as a baby diaper comprising a three-dimensional laminate (30) having a first layer (1) intermittently bonded to a second layer (2) by a heterophase polymer. The topsheet (24) comprises three-dimensional protrusions (9) in the first layer (1) which are not bonded to the second layer (2)．The heterophase polymer has an enthalpy of fusion of at least 10 J/g．The laminate may be used on the wearer-facing side (24) of the article as topsheet (24) and/or on the garment-facing side (26) as part of the backsheet (26). The first layer (1) may comprise natural fibers. An absorbent article with the three-dimensional laminate can prevent the first layer from being inadvertently bonded to the second layer in the area of the protrusions.
Patent EP-3683348-A1 (EP)
Title: Water delivery nozzles for chemistry dispensing system
Inventor: AFAJALPURKAR VINAYAK A
IPC: D06F39/02
Filed: 2020-01-13
Abstract: A laundry appliance (12) includes a drum (14) that is rotationally operable within a wash tub (16). A chemistry receptacle (18) is located proximate the drum (14). A chemistry dispensing module (10) is coupled to the chemistry receptacle (18) and has a prewash portion (20) and a main wash portion (22). A first fluid inlet (24) is coupled with the prewash portion (20) and a second fluid inlet (26) is coupled to the main wash portion (22). A fluid outlet (28) extends from the chemistry dispensing module (10) to a laundry treating chamber. A prewash nozzle (30) is coupled to the first fluid inlet (24) and the prewash portion (20). The prewash nozzle (30) includes an elongated arcuate body (32) that follows a curvature of the prewash portion (20) and defines a cyclonic flow path (34) from the prewash nozzle (30) to the fluid outlet (28).
Patent EP-3852407-A1 (EP)
Inventor: EISENDLE CHRISTIAN
IPC: H04W4/80
Filed: 2020-01-17
Abstract: In accordance with a first aspect of the present disclosure, an ultra-wideband (UWB) communication device is provided, comprising: a UWB communication unit being configured to establish and perform UWB radio communication with an external device, a radio frequency (RF) communication device being a radio frequency identification (RFID) tag, wherein the RF communication device is configured to receive at least one command from an external reader and to initiate a wake-up or a power-up of the UWB communication unit in response to receiving said command. In accordance with a second aspect of the present disclosure, a corresponding method of operating an ultra-wideband (UWB) communication device is conceived.
Patent EP-3660901-A1 (EP)
Inventor: OGAWA HIROYUKI
IPC: H01L27/11519
Filed: 2016-12-19
Abstract: The total chip area for a three-dimensional memory device can be reduced employing a design layout in which the word line decoder circuitry is formed underneath an array of memory stack structures. The interconnection between the word lines and the word line decoder circuitry can be provided by forming discrete word line contact via structures. The discrete word line contact via structures can be formed by employing multiple sets of etch masks with overlapping opening areas and employed to etch a different number of pairs of insulating layers and electrically conductive layers, thereby obviating the need to form staircase regions having stepped surfaces. Sets of at least one conductive interconnection structure can be employed to provide vertical electrical connection to the word line decoder circuitry. Bit line drivers can also be formed underneath the array of memory stack structures to provide greater areal efficiency.
Patent EP-3691043-A1 (EP)
Inventor: WANG YUNHE
IPC: H01R24/50
Filed: 2020-01-29
Abstract: There is provided a connector, including: outer conductor including a first outer conductor and a second outer conductor assembled together in such a way that they are slidably movable with respect to each other; center conductors arranged within the outer conductors and including a first center conductor and a second center conductor assembled together in such a way that they are slidably movable with respect to each other; an insulation seat to which the first outer conductor is fixed; and an elastic element one end of which abuts against the first outer conductor or the insulation seat, the first center conductor is also fixed to the insulation seat, so that the first outer conductor and the first center conductor are both in electrical contact with a first electrical component under a pressing force from the elastic element.