baber/WOPTO huggingface dataset:
Patent WO-0250516-A2 (WO)
Inventor: EGGELING CHRISTIAN
IPC: G01N15/14
Filed: 2001-12-20
Abstract: La présente invention concerne un procédé bien adapté à l'observation d'une molécule unique.  Selon ce procédé, on détecte la fluorescence ou le signal Raman de molécules uniques par comptage de photons.  On divise la séquence des photons détectés en intervalles de comptage en établissant la fin d'un intervalle de comptage après qu'un nombre prédéterminé de photons a été dénombré.  On détermine, pour les photons de chaque intervalle de comptage, des variables aléatoires telles que la durée de décroissance de la fluorescence, l'anisotropie du signal observé, etc., qui sont caractéristiques des molécules.  On construit un histogramme multidimensionnel comme une fonction des variables aléatoires, en utilisant les valeurs des variables mesurées dans chaque intervalle de comptage.  On peut utiliser des régions de l'histogramme pour déterminer comment les molécules sont distribuées par rapport aux sites de liaison, etc.  On peut alors choisir le signal provenant de régions sélectionnées des histogrammes pour procéder à une analyse sélective plus poussée permettant d'obtenir des résultats spécifiques d'espèce.
Patent WO-02093610-A2 (WO)
Title: Ablenksystem für ein teilchenstrahlgerät
Inventor: BRUNNER MATTHIAS
IPC: H01J37/147
Filed: 2002-03-04
Abstract: Ein Teilchenstrahlapparat und eine Vorrichtung zum energiekorrigierten Ablenken eines entlang einer Strahlachse einfallenden Teilchenstrahls um einen vorgegebenen Ablenkwinkel werden offenbart, wobei der Teilchenstrahl aus geladenen Teilchen mit um einen vorgegebenen Energiewert gestreuten Energien besteht. Die Vorrichtung weist einen Korrektor auf, wobei der Korrektor mittels eines ersten elektrischen Feldes und eines überlagerten ersten magnetischen Feldes Richtungsänderungen an den geladenen Teilchen in Abhängigkeit ihrer Energie vornimmt und wobei die Richtung der geladenen Teilchen mit dem vorgegebenen Energiewert beim Durchqueren des Korrektors beibehalten wird. Die Vorrichtung weist weiterhin einen dem Korrektor nachgeschalteten Ablenker auf, wobei der Ablenker mittels eines zweiten elektrischen Feldes oder mittels eines zweiten magnetischen Feldes die geladenen Teilchen, die den vorgegebenen Energiewert aufweisen, um einen vorgegebenen Ablenkwinkel von der Strahlachse weg ablenkt, wobei der Ablenker die geladenen Teilchen fokussiert. Weiterhin weist die Vorrichtung eine Steuerung zum Ansteuern des Korrektors und des Ablenkers auf.
Patent WO-03002764-A2 (WO)
Inventor: NEUMAIER MICHAEL
IPC: C12Q1/68
Filed: 2002-06-28
Abstract: Die Erfindung beschreibt ein Verfahren, bei dem über die Bestimmung der Expression von Glykoproteinantigenen der CEACAM-Familie therapeutisch nutzbare Verbindungen identifiziert werden können. Diese weisen Eigenschaften auf, die Bildung hyperplastischer Veränderungen, die als Vorläufer einer neoplastischen Transformation identifiziert wurden und zur Bildung eines Karzinoms führen können, zu verhindern bzw. die Normalisierung des Gewebes wiederherzustellen. Insbesondere betrifft die vorliegende Erfindung ein Verfahren zumIdentifizieren von Verbindung(en), die für eine Prävention der Tumorbildung oder zur Behandlung von Vorläuferstufen von Tumoren geeignet sind. Diese ausgewählten Verbindungen sind in der Lage durch Regulation der Genexpression die Apoptosempfindlichkeit von Zellen der Kolonschleimhaut, insbesondere der Vorläuferzellen zu erhöhen (bzw. eine Apoptoseresistenz erniedrigen). Des weiteren richtet sich die Erfindung auf ein diagnostisches Verfahren sowie auf die Verwendung der erfindungsgemäß identifizierten Zellen in pharmazeutischen Verbindungen zur Prävention der Tumorbildung und der Behandlung von Vorläuferstufen davon.
Patent WO-03009855-A2 (WO)
Inventor: JOMAA HASSAN
IPC: C07F9/38
Filed: 2002-07-18
Abstract: L'invention concerne des composés organophosphorés de formule générale (I), leur production, leurs utilisations pour l'activation de cellules T gamma/delta, pour le criblage d'inhibiteurs de l'enzyme GcpE et de l'enzyme LytB, ainsi que pour la prophylaxie et le traitement d'affections chez l'homme et l'animal.
Patent WO-03023060-A2 (WO)
Title: Verfahren und kit zur diagnostik oder behandlungskontrolle von brustkrebs
Inventor: KREHAN ALF-ANDREAS
IPC: B01L3/00
Filed: 2002-09-06
Abstract: Die vorliegende Erfindung bezieht sich auf ein Verfahren und ein Kit zur Diagnostik oder Behandlungskontrolle von Brustkrebs bei einem Menschen. Dieses Verfahren basiert darauf, dass in einer Blutprobe des Menschen das Vorhandensein oder Fehlen von mindestens zwei verschiedenen mRNS erfasst wird, die für verschiedene der Tumormarkerproteine EGF-R, CEA, Stanniocalcin, CK20, MAGE-3, GA733.2, MUC1, Her-2/neu, Claudin-7 und/oder PDGF- beta  kodieren und daraus auf das Vorhandensein von Mammakarzinomzellen in der Blutprobe und damit auf mögliche Metastasierung geschlossen wird.
Patent WO-03080070-A2 (WO)
Inventor: DAMON ROBERT EDSON
IPC: A61K31/4453
Filed: 2003-03-21
Abstract: L'invention concerne une combinaison, notamment une composition pharmaceutique, comprenant les principes actifs suivants : (i) un inhibiteur de HMG-CoA réductase ou un sel pharmaceutiquement acceptable de ce dernier ; (ii) (a) une séquence activatrice de la sécrétion de l'insuline ou un sel pharmaceutiquement acceptable de cette dernière ou (b) un agent insulino-sensibilisateur ou un sel pharmaceutiquement acceptable de ce dernier ; et, dans le cas d'une composition pharmaceutique, un excipient pharmaceutiquement acceptable.
Patent WO-2004013800-A2 (WO)
Title: Software for generating a computer application code and software description language
Inventor: ARCARO STEPHANE
IPC: G06F9/44
Filed: 2003-07-29
Abstract: The invention relates to a software generating the computer code of at least one part of a computer application from a description of the computer application part, by distributing said part between several code generators according to modifiable distribution rules. Each code generator translates the received description part in order to provide at least one part of said computer code in a respective language. Said invention also relates to a software description language, especially of the object language type for computer application modeling, and to a software allowing a computer application model to be textually or graphically built, in particular a man-machine interface model, and to provide a model description in said software description language.
Patent WO-2004030671-A2 (WO)
Title: Utilisation de 4-amino-quinazolines comme agents anticancereux
Inventor: BARNICKEL GERHARD
IPC: A61P19/02
Filed: 2003-08-25
Abstract: Cette invention a trait à l'utilisation de quinazolines correspondant à la formule (I), de leurs sels et de leurs solvates comme inhibiteurs de la protéine kinase B (PKB). Dans cette formule, R, R1, R2, R3, R4 et Y sont tels que définis dans la revendication 1.
Patent WO-2004055154-A2 (WO)
Inventor: MEIJER LAURENT
IPC: A61K31/404
Filed: 2003-12-17
Abstract: La présente invention concerne l'utilisation d'au moins un inhibiteur de kinase pour fabriquer des médicaments induisant une différentiation de cellules pileuses surnuméraires et de cellules de Deiter dans l'organe de Corti en développement.
Patent WO-9502040-A2 (WO)
Title: Nouvelles lignees cellulaires stromales provenant de la moelle osseuse humaine et leur utilisation
Inventor: THALMEIER KARIN
IPC: C12N15/85
Filed: 1994-07-07
Abstract: Une lignée cellulaire stromale de la moelle osseuse humaine se caractérise en ce que les cellules de cette lignée cellulaire, après irradiation entraînant l'interruption de leur développement, demeurent adhérentes, et cette lignée cellulaire est appropriée pour être utilisée comme couche nourricière en vue de faciliter la prolifération des globules sanguins.
Patent WO-9737032-A2 (WO)
Title: Preparation of microbial polyunsaturated fatty acid containing oil from pasteurised biomass
Inventor: BIJL HENDRIK LOUIS
IPC: A23L33/00
Filed: 1997-03-21
Abstract: The present invention discloses a microbial polyunsaturated fatty acid(PUFA)-containing oil with a high triglyceride content and a high oxidative stability. In addition, a method is described for the recovery of such oil from a microbial biomass derived from a pasteurised fermentation broth, wherein the microbial biomass is subjected to extrusion to form granular particles, dried and the oil then extracted from the dried granules using an appropriate solvent.
Patent WO-9821072-A2 (WO)
Inventor: KAUSCH ARMIN
IPC: G10K11/16
Filed: 1997-11-11
Abstract: L'invention concerne un dispositif et un procédé permettant d'éviter des atteintes auditives pouvant se produire par déclenchement des systèmes de retenue des occupants d'un véhicule, le dispositif fonctionnant avec une source sonore provoquant un évènement sonore primaire à niveau de pression acoustique n'entraînant pas d'atteintes auditives. Le niveau de pression acoustique est toutefois suffisamment élevé pour déclencher le réflexe dit stapédien de l'oreille humaine, par lequel, sous l'effet de pressions acoustiques élevées, la sensibilité de l'oreille est réduite, et l'évènement sonore subséquent ne présente, sur l'oreille interne, qu'une fraction des effets négatifs de l'évènement sonore primaire. L'évènement sonore primaire ne doit être déclenché que dans un temps suffisamment court avant l'évènement sonore secondaire qui se produit lors du déclenchement du système de retenue et qui présente un niveau de pression acoustique entraînant des atteintes auditives.
Patent WO-9905264-A2 (WO)
Title: Herstellung humaner mutierter proteine in humanen zellen mittels homologer rekombination
Inventor: STERN ANNE
IPC: C12N9/04
Filed: 1998-07-22
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung von Muteinen eukaryontischer Polypeptide in eukaryontischen Zellen mittels homologer Rekombination. Weiterhin betrifft die Erfindung ein Verfahren zur Herstellung humaner Zellen, die zur Herstellung humaner mutierter Proteine geeignet sind. Schließlich betrifft die Erfindung die durch das Verfahren hergestellten humanen Zellen und daraus erhältliche mutierte humane Proteine, sowie pharmazeutische Präparate, die diese Muteine enthalten.
Patent WO-9913083-A2 (WO)
Inventor: INZE DIRK
IPC: C12N15/09
Filed: 1998-09-07
Abstract: Provided are DNA sequences encoding cell cycle interacting proteins as well as to methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Also described is a method for controlling or altering growth characteristics of a plant and/or a plant cell comprising introduction and/or expression of one or more cell cycle regulatory proteins functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins. Also provided is a process for disruption plant cell division by interfering in the expression of a substrate for cyclin-dependent protein kinase using a DNA sequence according to the invention wherein said plant cell is part of a transgenic plant. Further described are diagnostic compositions comprising the aforementioned DNA sequences, proteins and antibodies. Methods for the identification of compounds being capable of activating or inhibiting the cell cycle are described as well. Furthermore, transgenic plant cells, plant tissue and plants containing the above-described DNA sequences and vectors are described as well as the use of the aforementioned DNA sequences, vectors, proteins, antibodies and/or compounds identified by the method of the invention in plant cell and tissue culture, plant breeding and/or agriculture.
Patent ES-2078837-A2 (ES)
Title: Pyranometer shadow band automatic positioning system.
Inventor: CREMADES OLIVER LAZARO
IPC: G01J5/28
Filed: 1992-12-04
Abstract: Pyranometer shadow band automatic positioning system. The purpose of the invention is to automate the operation of systems that measure the sun's diffuse irradiance, facilitating data acquisition and eliminating the manual work of correctly positioning the shadow band. This invention is adaptable to the various models based on the shadow band method, whether currently existing or not. However, there will be small variations in the mechanical system. The invention is characterized by automatically blocking the incidence of direct radiation upon the solar irradiance measuring instrument (pyranometer).
Patent WO-03080491-A2 (WO)
Title: Elevator and guide fixing bracket for an elevator
Inventor: VALJUS PETTERI
IPC: B66B/
Filed: 2003-03-18
Abstract: Elevator, preferably an elevator without machine room, comprising at least an elevator car (101) moving along guide rails (1), a counterweight (102) moving along guide rails (2) and an elevator motor (106) driving them, wherein the guide rails are fixed in place by means of guide fixing brackets (112). The width of the guide fixing bracket (112) in the vicinity of the car guide rails (1) is substantially equal to the width of the car guide rail plus the thickness of the rail clips in the guide fixing bracket.
Patent FR-2337517-A2 (FR)
Title: Mfr. of dance or ballet shoes - includes forming sole and upper on lase and machine sewing
IPC: A43B5/12
Filed: 1976-01-09
Abstract: The manufacture of dance or ballet shoes which are entirely sewn by machine. The upper and lining are cut out by an electric saw or by a punch to the exact size of the shoe required. The edges of the frame of the point are fastened (1) on the middle of the sole (3) on a last. They are then put into the point of the upper by the introduction of the last or an arch can be bonded to the sole before the last is introduced. The exterior sole is then bonded to the inner sole without prior preparation.
Patent FR-2365637-A2 (FR)
Title: Oxide ore leached to dissolve lead - which is pptd. as lead chloride and reduced by hydrogen to obtain high purity lead
Inventor: LAMBERT BERNARD
IPC: C22B15/00
Filed: 1976-09-24
Abstract: Oxide cpd., contg. Pb and other nonferrous metals is treated a described in the parent patent, a hydrometallurgical process using a hot aq. phase contg. >=1 gram-equiv. of Cl ions/litre and with pH 6, so the Pb and other metals are dissolved. In this Addn., the Pb is recovered from the soln. as PbCl2 crystals, which are then melted and reduced by H2. Redn. is pref. 750-850 degrees C., esp. using H2 diluted by an inert gas and injected into the molten PbCl2. Metallic lead with high purity can be obtd.; the Cl ions are recovered as HCl which is recycled; and the reducing agent employed is inexpensive.
Patent FR-2394229-A2 (FR)
Title: Slide:in printed circuit board assembly - has horizontal circuit board supporting vertical boards in guide slots with contacts
IPC: H05K7/14
Filed: 1977-06-07
Abstract: The slide-in printed circuit board assembly consists of a horizontal printed circuit board with parallel guide slots to hold a series of vertical boards. The horizontal board slides between guide slots forming part of a frame or housing. The lower edges of the vertical boards have contact pads distributed along them corresponding to contacts inside the lower guide slots. The side edges of the horizontal board also have contact pads that likewise touch contacts in the frame's lateral guide slots. The insertion force is zero. The frame's lateral guide slots are part of terminal strips with projecting pin contacts for external connections.
Patent FR-2454555-A2 (FR)
Title: Insert type nut fixing - is protected when subjected to jets of water by sheet cover making it blind
IPC: F16B37/06
Filed: 1979-04-18
Abstract: The inserted type nut (10) is provided with protection when subjected to jets of water. On its front face is a sheet with square receiving holes. A polygonal base is below the front face (11) with an edge (32) pressing against the receiver. The lower part of the base has four stops (17) chamfered so as to form a cone of revolution, with a square base. The edge pressing on the base is perpendicular to the axis of the nut to form a stop when the front of the base is placed in the hole.
Patent FR-2496773-A2 (FR)
Title: Wind-driven generator with controlled axis of orientation - has rotor speed control provided by varying angle of attack of rotor plane w.r.t. to wind velocity
Inventor: TREMOLLIERE ELIANE
IPC: F03D7/02
Filed: 1980-12-24
Abstract: The rotor is equipped with blades and jointed to a rotary shaft with a damping arrangement. The axis is jointed to rotate about a horizontal axis in a vertical plane between two upright members on a base which is turned about a vertical axis into the wind, by a wind vane and motorised gearing. Angular movement of the axis in the vertical plane parallel to the direction of the wind is controlled so that the surface presented to the wind by the plane of the rotor is enough to maintain the rate of rotation which is constant, or to vary it in accordance with demand. The rotational speed of the device, and its attitude towards the wind direction is controlled by a device measuring the speed of the rotor. The generator has a quadrilateral deformable structure having at least two members of unequal length which are articulated on a lower platform, rotatable about a vertical axis, and an upper platform supporting the rotor and generator.
Patent FR-2531478-A2 (FR)
Title: Subframe or prefabricated frame for openings in buildings.
Inventor: MALIE LOUIS
IPC: E06B1/24
Filed: 1982-08-06
Abstract: Subframe or prefabricated frame for openings in buildings. The subject of the present invention is improvements to Patent Application N DEG 78 08427 by the same Applicant relating to a prefabricated reinforced concrete monobloc frame. The subframe according to the present invention of the type of those comprising means of immobilisation of the strap hinges of shutters when the latter are pushed back against the masonry of the wall is characterised substantially in that the means of immobilisation are each constituted by at least one plate 12 fixed to one of the jambs 3 of the subframe 1 provided with at least one catch 13 protruding from the masonry of the wall and by at least one locking device 15 carried by the shutter 5 and engaging with the said catch 13 in order to lock the strap hinges 6 in rotation. The purpose of the improvements according to the present invention is to simplify the production of such means.
Patent FR-2533229-A2 (FR)
Title: Support for the attachment of microorganisms
Inventor: GEIRNAERT GILLES
IPC: C12N11/14
Filed: 1982-09-21
Abstract: Use of the support according to the main patent for the immobilisation of microorganism cells, wherein the application is carried out on hybridoma cells for the continuous production of monoclonal antibodies by passing the aforementioned cells, in a suitable culture medium, into a reactor containing a fixed bed of the aforementioned support.
Patent FR-2623814-A2 (FR)
Title: Catalyst for cracking hydrocarbon feedstocks comprising an offretite, a zeolite and a matrix
Inventor: MARCILLY CHRISTIAN
IPC: B01J29/50
Filed: 1987-11-30
Abstract: Process for catalytic cracking in the presence of a catalyst based on a zeolite and an offretite which are diluted in a matrix. The catalyst employed in the process contains in particular:     a) from 20 to 95 % by weight of at least one matrix, b) from 1 to 70 % by weight of at least one zeolite with open structure in which the opening of the main channels is at least 7 x 10<-10> m, c) from 0.05 to 40 % by weight of at least one offretite in which the opening of the main dodecagonal channels is smaller than 6.8 x 10<-10> m, which has an SiO2/Al2O3 molar ratio of approximately 15 to approximately 500, elementary crystal lattice constants a and c of approximately 1.285 to 1.315 nm in the case of a and approximately 0.748 to 0.757 nm in the case of c, respectively, and a potassium content lower than 1.5 % by weight.   The process makes possible an appreciable increase in the octane number of the petrol produced by cracking.
Patent FR-2628803-A2 (FR)
Title: Constant velocity sliding joint for motor vehicle - has tapered ball bearing carrier tracks increasing differential longitudinal forces and returning carriers to mean position
Inventor: POULIN BERNARD
IPC: F16D3/24
Filed: 1988-03-18
Abstract: The transmission comprises a shaft with three, equi-spaced radial arms terminating in a spherical end (3). A carrier (12) with spherical bearing surface (4), rotates about the arm (3). This assembly slides with a tube (10) with three pairs of equi-spaced longitudinal tracks (11). Ball bearings (15) contained in a cage (16) are interposed between the tracks (11) and carriers (12). The bearing surfaces (14a,14b) of the carriers are tapered such that the distance between these surfaces and the tracks (11) increase from the central stops (17). ADVANTAGE - Ball bearings and carriers (12) are maintained in mean relative positions and rolling contact is thus maintained.
Patent FR-2661365-A2 (FR)
Title: Automatic guillotine for cutting paper
Inventor: PIERRE CALLET
IPC: B26D7/06
Filed: 1990-04-27
Abstract: The invention relates to an automatic guillotine for making pads from stacks of paper, by cutting, and including a layout board (1) on which the stacks (6) to be cut are located, a blade (2) which can be moved in an essentially vertical plane by actuating means, means for discharging the pads formed and adjustable means for advancement which are intended to cause each stack of paper to be cut to advance with a translational step by step drive movement depending on the desired dimensions of the pads to be made, whilst the means for advancement and the cutting actuating means are slaved so that the effective cutting of the stacks takes place after each advancement step and while the said stacks are immobilised. The guillotine according to the invention is noteworthy in that the means for advancement include a conveyor (10a, 10b) which is moved in a translational movement by a motor (11), controlled by a computer (15), itself slaved to the cutting device, in order to allow programmed cutting of each stack (6).
Patent WO-0069728-A2 (WO)
Title: Recipient d'aliments
Inventor: BARNES SUSAN MARIE
IPC: B65D77/24
Filed: 2000-05-16
Abstract: L'invention concerne un pot (10) de plastique moulé comprenant un fond (13) et une paroi 14 latérale. Un ustensile de plastique tel qu'une cuiller (16) à l'aide de laquelle la nourriture contenue dans le pot (10) peut être consommée, est moulé d'un seul tenant avec le pot et est relié aux extrémités supérieure et inférieure du pot par une articulation située à l'extrémité du manche (17). La longueur de l'ustensile correspond approximativement à la profondeur du pot et la paroi (14) latérale du pot présente un logement (15) dans lequel l'ustensile peut être inséré. Des ergots (20) retiennent l'ustensile dans le logement jusqu'à son utilisation. Lorsqu'on veut l'utiliser, on extrait l'ustensile (16) de son logement (15) et on le rompt au niveau de l'articulation.
Patent WO-0153999-A2 (WO)
Title: Procede de conception, de modelisation ou de fabrication d'un empilement de bandes de base de transmission
Inventor: FERRIS GAVIN ROBERT
IPC: G06F17/50
Filed: 2001-01-24
Abstract: L'invention concerne un procédé de conception, de modélisation ou de fabrication d'un empilement de bandes de base de transmission, consistant à : (a) établir une description d'un ou de plusieurs des paramètres suivants de l'empilement de bandes de base : (i) besoins en ressources ; (ii) fonctions ; (iii) comportement ; et (b) à utiliser cette description comme entrée pour un logiciel comprenant une couche machine virtuelle optimisée pour un processeur de signaux numériques de transmission afin de générer une émulation de l'empilement de bandes de base à concevoir, modéliser ou fabriquer.