baber/WOPTO huggingface dataset:
Patent CA-2202875-A1 (CA)
Inventor: SANDBERG HELENA
IPC: A61P7/04
Filed: 1995-11-14
Abstract: Les protéases tendent généralement à réduire l'activité du facteur de coagulation VIII en dégradant sa molécule. Un procédé permet de limiter l'influence néfaste des protéases dépendantes des métaux sur des molécules du facteur VIII recombiné, par l'adjonction d'un inhibiteur des protéases dépendant des métaux à une solution après la récolte. Cette solution peut être la solution de récolte ou toute solution aqueuse introduite dans l'étape d'isolation primaire ou la quittant, celle-ci étant l'étape initiale de la séquence de purification. L'inhibiteur est choisi parmi: 1) des agents complexants qui présentent plus d'affinité pour l'ion métal de la protéase que pour celui ou ceux stabilisant la molécule du facteur VIII, et 2) des composés à structure apparentée au substrat naturel de la protéase et contenant une fraction électronégative. La présence d'un inhibiteur - un agent complexant de préférence - après la récolte permet une période de récolte prolongée et une production considérablement supérieure ainsi que le maintien de l'essentiel de l'activité du facteur VIII. L'invention concerne également une solution aqueuse contenant du facteur VIII recombiné qui a été purifié par ce procédé ainsi que l'utilisation d'une telle solution aqueuse pour fabriquer un médicament devant être administré à un patient qui présente des symptômes d'hémophilie. Un procédé permet de traiter l'hémophilie par l'administration d'une quantité thérapeutiquement efficace du facteur VIII recombiné qui a été purifié selon ce procédé.
Patent CA-2203165-A1 (CA)
Title: Synthetic ige membrane anchor peptide immunogens for the treatment of allergy
Inventor: WANG CHANG YI
IPC: C07K14/02
Filed: 1995-10-25
Abstract: The present invention relates to a method for eliciting the production in healthy mammals, including humans, of high titer antibodies specific for sites on the extracellular segment of the anchor domain of the membrane-bound .epsilon. heavy chain of B cell-expressed humain IgE by the use of a composition comprising a synthetic peptide immunogen containing extracellular membrane anchor sites, to reduce IgE-secreting B leukocytes and allergen-induced IgE production. It also relates to the use of optimally designed, carrier protein free, IgE .epsilon.-chain related immunogens as key components in a synthetic vaccine to provide an immunotherapy for the treatment of allergy. The subject peptides contain immune stimulator sequences, including a tandemly linked helper T cell epitope, to aid in stimulating the immune response towards the mIgE membrane anchor domain.
Patent CA-2205716-A1 (CA)
Title: Composite tank for industrial finishing equipment
Inventor: WHITEHEAD J STEVE
IPC: B08B3/00
Filed: 1997-05-20
Abstract: A composite tank is provided for use with industrial finishing equipment. The tank includes a generally planar bottom plate. Wall panels made from fiberglass reinforced plastic are attached to the bottom plate and extend generally upwardly therefrom so that the wall panels cooperate with the bottom plate to define an interior region of the tank. The upwardly-facing surface of the bottom plate and portions of the wall panels adjacent to the bottom plate are coated with fiberglass reinforced plastic to provide the tank with a seamless and water impermeable interior.
Patent CA-2206500-A1 (CA)
Title: Titanium filled thick mantle, soft covered multi layered golf ball
Inventor: NESBITT DENNIS
IPC: A63B37/12
Filed: 1997-05-29
Abstract: The present invention is directed to improved multi-layer golf ball compositions and the resulting regulation balls produced using these compositions.  In this regard, a smaller and lighter core is produced and metal particles, or other heavy weight filler materials, are included in the cover compositions.  This results in a  molded  golf  ball  exhibiting  enhanced  interior  perimeter weighting. Preferably, the particles are included in a relatively thick inner cover layer (or mantle) of a solid, three-piece multi-layered golf ball.  The size and weight of the core is reduced in order to produce an overall golf ball which meets, or is less than, the 1.62 ounce maximum weight limitation specified by the United States Golf Association.         It has been found that the combination of the present invention produces a golf ball with an increased moment of inertia and/or a greater radius of gyration and thus generates lower spin.          This results in a golf ball exhibiting enhanced distance without substantially effecting the feel and durability characteristics of the ball.
Patent CA-2207079-A1 (CA)
Title: Combination air bar and hole bar flotation dryer
Inventor: BRIA MICHAEL P
IPC: F26B21/12
Filed: 1995-12-05
Abstract: Apparatus and process for the non-contact drying of a web of material. The apparatus includes air flotation nozzles for floating the web, and direct air impingement nozzles (10) for enhanced drying of the web. A  plurality of air flotation nozzles or air bars (A, B) are mounted in one or more sections of a dryer enclosure in air-receiving communication with headers (11), preferably both above and below the web for the contactless convection drying of the web. In conjunction with these air flotation nozzles, one or more sections of the dryer also include direct impingement nozzles (10) such as hole-array (H, B) or slot bars. The drying surface of the web is thus heated by both air issuing from the air flotation nozzles and from the direct impingement nozzles. As a result, the dryer has a high rate of drying in a small, enclosed space while maintaining a comfortable working environment.
Patent CA-2209102-A1 (CA)
Inventor: TANAKA RIE
IPC: C07B53/00
Filed: 1996-10-30
Abstract: La présente invention concerne un procédé de production d'alcools de sulfures de transvinyle actifs sur le plan optique, représentés par la formule générale (III), dans laquelle R?1¿ représente alkyle ou aryle. Ce procédé comprend la réduction de cétones de sulfures de transvinyle avec un agent réducteur au borane, en présence d'une oxazaborolidine active sur le plan optique et d'un additif.
Patent CA-2209662-A1 (CA)
Title: Enhanced overflow call processing
Inventor: FRAZIER CATHLEEN
IPC: H04Q3/66
Filed: 1996-01-11
Abstract: A system and method for Enhanced Overflow Call Processing redirects calls which cannot be completed to alternate terminations. An originating switch (212) queries a network database (208) for an alternate termination for the call each time the originating switch detects that the call cannot be completed to the current termination. The network dababase determines the alternate termination for each query using a hierarchical set of multi-branch overflow statements, which are configured by the user (212-10). A set of overflow statements is selected by the network database on the original termination of the call. The set of overflow statements is searched hierarchically until an active overflow statement is found. This overflow statement then controls all queries relating to that call. The reason the call was not completed is used to select either an alternate termination to which the call is to be routed or a particular treatment, such as a busy signal or network message, which is to be applied to the call. If an alternate termination is selected the originating switch routes the call to the alternate termination. The process then repeats until either the call is completed, the overflow statement specifies a treatment is to be applied, or a predetermined number of completion attempts to alternate terminating have occurred.
Patent CA-2211997-A1 (CA)
Title: Valve connector
Inventor: VAN DER BLOM NICOLAAS
IPC: F04B41/00
Filed: 1996-02-02
Abstract: By a universal valve connector for inflation valves of vehicle tyres (Sclaverand, Dunlop-Woods, or Schrader), whose connector consists of a connector housing (368), which partly is connected to a pressure source, preferably a hand or foot pump, and which partly has a coupling hole (5) with a diameter corresponding to the diameter of the valve, which is to be connected, where the coupling hole is equipped with a securing means for securing on the valve, plus a sealing means against valves of different sizes. This is achieved by the sealing means (366) being mounted coaxially in the connector housing (368) and being established on at least two parallel, separate levels, having the centre line (4) of the connector housing (368), which is coaxial to the centre line of the valve, as its normal, where the minor diameters of the sealing means approximately correspond to the major diameter of the current valve dimensions, on which the connector is mounted when used, that the sealing means (366), closest to the opening (8) of the coupling hole (5) in the connector housing (368) has the biggest minor diameter, while the sealing means (366) farthest from the opening (8) of the coupling hole in the connector housing (368) has the smallest minor diameter, and diameters between the extremes are lying corresponding separate distances between these extremes. The valve connector has the possibility of automatically adjust itself to the valve in question and if needed to activate the central core of a Schrader valve. Also, it is possible to use the connector with existing pumps.
Patent CA-2212852-A1 (CA)
Inventor: PERDOMI GIANNI
IPC: B32B27/32
Filed: 1996-12-13
Abstract: Multilayer thermoshrinkable films in which at least one layer (a) is based on a polyolefin composition comprising a propylene copolymer and having particular crystallinity characteristics, and at least one layer (b) comprising a linear copolymer of ethylene with one or more .alpha.-olefins (LLDPE). The films are characterized by an optimum balance of physicomechanical properties, processability and lap seal strength at low temperatures.
Patent CA-2218872-A1 (CA)
Title: Preparation and use of sulfated oligosaccharides
Inventor: PARISH CHRISTOPHER RICHARD
IPC: A61K6/898
Filed: 1996-04-24
Abstract: Sulfated oligosaccharides, wherein the oligosaccharide has the general formula (I): R1-(R x)n-R2, wherein R1 and R2 and each R x represents a monosaccharide unit, all of which may be the same or different, adjacent monosaccharide units being linked by 1.fwdarw.2, 1.fwdarw.3, 1.fwdarw.4 and/or 1.fwdarw.6 glycosidic bonds and n is an integer of from I to 6, and use thereof as anti-angiogenic, anti-metastatic and/or anti-inflammatory agents.
Patent CA-2221210-A1 (CA)
Title: Air distribution arrangement for paint spray booth
Inventor: JOSEFSSON LEIF E B
IPC: B05B15/12
Filed: 1996-05-14
Abstract: An air distribution apparatus (36) in a paint spray booth plenum (32) for increasing the uniformity of down draft velocities from the plenum (32) to the spray booth paint application zone (24). The increased uniformity of down draft velocities correspondingly increases paint transfer efficiency and minimizes paint overspray buildup in the paint application zone (24). The improved air distribution apparatus (36) includes airflow regulating means (38) and flow directing means which cooperate to distribute airflow substantially evenly across the plenum floor (14) and into the paint application area (24). In the preferred embodiment, a plurality of perforated plates (46, 48) and guide vanes (70, 71) are used to control the rate and direction of airflow in the plenum (32). The invention also provides for the adjustment of the rate and direction of flow through the use of slidable plates and adjustable guide vanes.
Patent CA-2221685-A1 (CA)
Title: A cartesian loop transmitter
Inventor: KENINGTON PETER BLAKEBOROUGH
IPC: H03F1/30
Filed: 1996-05-22
Abstract: A cartesian loop transmitter is disclosed. The disclosed cartesian loop includes various fine and coarse power control circuits that allow power control over a wide range and that allow fine control in very small increments. The disclosed cartesian loop also includes a loop filter which minimized noise in the loop, a DC nullin circuit, an instability detection circuit, a mask detection circuit, an undervoltage protection circuit, a temperature protection circuit and an automatic phase calibration circuit.
Patent CA-2222123-A1 (CA)
Inventor: ARENA CHANTAL
IPC: C23C16/42
Filed: 1996-05-28
Abstract: Titanium is deposited onto a semiconductor interconnect to form a salicide structure by plasma-enhanced chemical vapor deposition. The reactant gases, including titanium tetrachloride, hydrogen and optionally argon, are combined.  A plasma is created using RF energy and the plasma contacts the rotating semiconductor material (11). This causes titanium to be deposited which reacts with exposed silicon to form titanium silicide (67, 68 and 69) without any subsequent anneal. Other titanium deposited on the surface, as well as titanium-rich silicon compositions (TiSix wherein X is 2), are removed by chemical etching. If only about 40 .ANG. of titanium is deposited, it will selectively deposit onto the silicon structure without coating the oxide spacers of the interconnect. In this embodiment the need to chemically etch the substrate is eliminated.
Patent CA-2226193-A1 (CA)
Title: Spark ignited internal combustion engine with multiple event fuel injection
Inventor: YANG JIALIN
IPC: F02D41/30
Filed: 1998-01-05
Abstract: A spark ignited, reciprocating internal combustion engine, including a piston housed within a cylinder closed by a cylinder head has a fuel system for injecting fuel directly into the engine cylinder so as to achieve a homogeneous mixture with the fuel injection system injecting a first fraction of fuel during a first injection event and a second fraction of fuel during a second injection event.
Patent CA-2227066-A1 (CA)
Title: Barrel assembly with axially stacked projectiles
Inventor: O'DWYER JAMES MICHAEL
IPC: F42B14/00
Filed: 1996-07-19
Abstract: A barrel assembly (10) having a plurality of projectiles (11) stacked axially within the barrel (12) together with discrete selectively ignitable propellant charges (13) for propelling the projectiles (11) sequentially through the muzzle of the barrel (12) is provided with adjacent projectiles (11) separated from one another by locating means (13) independent of the projectiles. The locating means may be a solid propellant charge (13) located between adjacent projectiles or it may be a rigid casing (122) for the propellant. When subject to an in-barrel load a rear skirt portion of the active projectile (11) is expanded outwardly by the interaction between an inwardly reducing recess (14) formed in the rear end of a projectile and the nested complementary leading portion of the propellant charge (13) or propellant casing (122).
Patent CA-2227389-A1 (CA)
Title: Dual seal fitting for enabling quick measurement of brake cylinder pressure
Inventor: JOHNSTON GREGORY L
IPC: G01L19/00
Filed: 1998-01-20
Abstract: A dual  seal coupling fitting enables quick measurement of pressure.  The fitting includes primary and secondary valves and has one end shaped like a male portion of a quick coupler and another end screwable into a threaded bore defined in a pressure bearing housing.  The fitting defines first and second cylindrical sections in communication with each other.   The primary valve situates in the first section,  the secondary valve in the second section.   The primary valve includes a valve stem with a poppet head.  A first mechanism compresses the poppet head against an outer valve seat to close the primary valve thereby preventing leakage of pressure.   The secondary  valve  features  a  cylindrical  seat  piece  and  a retainer.   The piece secures within the second section and defines through itself an inner bore.  The piece at one end forms an inner valve seat and at an opposite end situates adjacent the first mechanism.  The retainer has at one end a post approximate a terminal end of the valve stem within the inner bore.   The retainer also has a check valve retained within an annular recess defined about a base of the post.  A second mechanism compresses the check valve against the inner valve  seat  to  close  the  secondary  valve  thereby  further preventing leakage of pressure.  Mating a female portion of a quick  coupler  to  the male portion opens  the primary and secondary valves and enables quick measurement of the pressure via a gage attached to the other end of the female portion.
Patent CA-2227518-A1 (CA)
Title: Procede de fabrication d'une bande abrasive sans raccord, pourvue d'un revetement
Inventor: CHRISTIANSON TODD J
IPC: B24D3/28
Filed: 1996-08-01
Abstract: La présente invention concerne un procédé de fabrication d'une bande abrasive souple, pourvue d'un revêtement. Ce procédé comprend les étapes suivantes: montage d'un substrat de support en boucle sans fin, sans raccord, présentant une surface avant visible et une surface arrière tendue sur la surface périphérique d'un support provisoire; mise en place d'une matière de renforcement fibreuse continue sur la surface avant, sur plusieurs tours; application d'un revêtement d'un premier précurseur de liant sur cette surface avant; exposition de ce revêtement à des conditions efficaces pour solidifier ce premier précurseur de liant et fixer la matière fibreuse de renforcement à la surface avant pour constituer un élément de soutien renforcé sans fin et sans raccord; application d'un revêtement abrasif, comprenant des particules abrasives et un adhésif, sur la surface arrière ou avant.
Patent CA-2228434-A1 (CA)
Title: Dispositif de mesure et procede pour mesurer des objets
Inventor: MAKKONEN VEIJO SAKARI
IPC: G01B5/04
Filed: 1996-08-01
Abstract: L'invention concerne un dispositif de mesure (2) tenu à la main et un procédé pour mesurer des objets. Le dispositif de mesure comprend un moyen (12) pour détecter l'information de mesure, à partir du mouvement relatif entre l'objet (8) à mesurer et le dispositif de mesure (2), ainsi qu'un moyen d'affichage (15) de l'information de mesure, adapté au dispositif de mesure (2). Le dispositif comprend en outre un moyen pour couper ou sectionner l'objet à mesurer.
Patent CA-2229752-A1 (CA)
Title: Control method for the manufacture of oriented plastics tubes
Inventor: CHAPMAN PETER GLANVILLE
IPC: B29C48/92
Filed: 1996-08-16
Abstract: A method of expanding a tube of plastics material is disclosed in which a longitudinally travelling tube (10) is progressively diametrically expanded by internal fluid pressure in an expansion zone (20) between an upstream plug (24) and an expandable downstream plug (26). Expansion of the tube is controlled in response to parameters which directly or indirectly indicate variation in the relative velocity at which material is delivered to and removed from the expansion zone, such as detecting upstream tube velocity (38), early expansion diameter (36), axial force (39) on a sizing device (28) or the tube diameter (41) just before the expansion zone.
Patent CA-2231734-A1 (CA)
Inventor: PATEL ARVIND D
IPC: E21B21/06
Filed: 1997-07-31
Abstract: A method of removing the filter cake formed from invert emulsion compositions including an oleaginous, a non-oleaginous and an acid sensitive surfactant to an oil and gas well are disclosed. The acid sensitive surfactant is selected so that the invert emulsion can be broken and residual filter cake solids made water-wet upon the addition of an acidic wash fluid to the well.
Patent CA-2233835-A1 (CA)
Title: Surface wave device balun resonator filters
Inventor: DAI JI-DONG
IPC: H03H9/64
Filed: 1998-04-01
Abstract: A surface wave device comprises first and second SPUDT (single phase unidirectional transducer) resonator filters (72, 74) each comprising first and second transducers, which are preferably RSPUDTs (resonant SPUDTs), the resonator filters being the same except that one transducer (R1M) of the second resonator filter is a mirror image of the corresponding transducer (R1) of the first resonator filter to provide a phase difference of 180°. The surface wave device serves as a balun by having an unbalanced signal connection (78) to the first transducers, and a balanced signal connection (84, 84') comprising signal connections to the second transducer of each of the first and second resonator filters. The resonator filters can be arranged side by side on a common piezoelectric substrate (76).
Patent CA-2238283-A1 (CA)
Inventor: THOMPSON W JOSEPH
IPC: A61K31/00
Filed: 1998-05-20
Abstract: This invention provides a method to identify compounds potentially useful for the treatment of neoplasia in mammals. The phosphodiesterase inhibitory activity of a compound is determined along with COX inhibitory activity. Growth inhibitory and apoptosis inducing effects on cultured tumor cells are also determined.  Compounds that exhibit phosphodiesterase inhibiton, growth inhibition and apoptosis induction, but not substantial prostaglandin inhibitory activity, are desirable for the treatment of neoplasia. Such compounds are useful for pharmaceutical compositions and uses for treating neoplasia.
Patent CA-2239481-A1 (CA)
Inventor: BREUNINGER MANFRED
IPC: B01J23/72
Filed: 1998-06-03
Abstract: A process for the conversion of non-.alpha.-tocopherols into .alpha.-tocopherol by the catalytic permethylation of at least one non-.alpha.-tocopherol comprises using as the methylating agent methanol in the near-critical or super-critical pressure and temperature region or a mixture which is equivalent to methanol and which consists of hydrogen and carbon monoxide and/or carbon dioxide, and as the catalyst a mixed oxide catalyst which is produced from hydrotalcites and which has at least copper and magnesium oxide as well as at least one oxide of a trivalent metal, e.g. aluminium oxide, iron(III) oxide, vanadium oxide, chromium oxide and/or gallium oxide. The non-.alpha.-tocopherol or non-.alpha.- tocopherol mixture, optionally present in a raw material, to be converted into .alpha.-tocopherol is preferably dissolved in an inert solvent, e.g. an alkane of medium molecular weight, a cyclic alkane or an aromatic hydrocarbon.   The product of this process has a very high content of .alpha.-tocopherol, which is the biologically most valuable tocopherol.
Patent CA-2242698-A1 (CA)
Title: Generation of bubbles for friction-reducing ship and method for reducing skin-friction
Inventor: YOSHIDA YUKI
IPC: B63B1/38
Filed: 1998-07-09
Abstract: A method is provided for reducing skin-friction of a ship moving through bubbly flow fields generated in proximity of hull surfaces by jetting gas through a plurality of jet nozzles provided on hull surfaces of the ship. The gas flow rate is controlled so as to establish a peak void fraction in a turbulent boundary layer, by applying an observation that the location of a peak void fraction shifts away in a direction normal to the hull surface with increasing gas flow rate through the jet nozzles.
Patent CA-2245754-A1 (CA)
Title: Agent for oral intake, its production and use
Inventor: TEWES-SCHWARZER PETRA
IPC: A61K9/20
Filed: 1998-08-25
Abstract: The invention relates to an agent for oral intake containing at least one compressed, non-toxic carrier which is at least partially broken down, or can be broken down, or is eliminated or can be eliminated via the digestive tract, whereby the carrier, after expanding in the stomach, has a sponge-like structure, characterized in that the carrier, at least partially, has a collagen structure; it also relates to a process for the production of the agent of the above-mentioned type, wherein a fine-pore sponge consisting of collagen and having a density ranging from 0.005 g/cm3 to 1 g/cm3 - which has optionally been treated with at least one active ingredient and/or additive prior to the pressing procedure, optionally in the presence of a mold-release agent - is compressed to half to one-fiftieth, preferably one-third to one-thirtieth of its original size, and it also relates to the use of this agent and of this process.