baber/WOPTO huggingface dataset:
Patent AU-2005230837-A1 (AU)
Title: 1,3,4-oxadiazol-2-ones as PPAR delta modulators
Inventor: GOERLITZER JOCHEN
IPC: A61K31/4245
Filed: 2005-03-30
Abstract: The present invention is directed to 1,3,4-oxadiazolones, compounds of formula I and their pharmaceutically acceptable salts stereoisomers, tautomers, or solvates thereof. Novel compounds include those of formula I, in which radicals are as defined herein. The compounds of this invention are modulators of PPARdelta and therefore useful as pharmaceutical agents, especially for the treatment of demyelinating diseases and disorders of fatty acid metabolism and glucose utilization.
Patent AU-2005318369-A1 (AU)
Title: mRNA ratios in urinary sediments and/or urine as a prognostic and/or theranostic marker for prostate cancer
Inventor: VERHAEGH GERALD
IPC: C12Q1/68
Filed: 2005-12-23
Abstract: Described herein are methods and kits for prognosis of prostate cancer in a subject. The methods comprises: (a) determining the ratio of PCA3 and PSA expression in a urine sample and (b) correlating the value of the PCA3/PSA ratio with the aggressiveness and mortality risk of prostate cancer in the subject. Kits for prognosing prostate cancer are also described. More particularly, the present invention features a method for prognosing prostate cancer in a biological sample of a patient comprising: assessing the amount of a prostate cancer specific PCA3 mRNA and the amount of PSA in the biological sample; determining a ratio value of this amount of prostate cancer specific PCA3 mRNA over the amount of PSA; comparing the ratio value to at least one predetermined cut-off value, wherein a ratio value above the predetermined cut-off value is indicative of a higher risk of mortality of prostate cancer as compared to a ratio value below the predetermined cut-off value.
Patent WO-2006122355-A1 (WO)
Title: Systeme et procede pour ameliorer l'analyse de substances chimiques par rqn
Inventor: CHISHOLM WARRICK PAUL
IPC: G01R33/44
Filed: 2006-05-16
Abstract: L'invention concerne un procédé d'analyse d'une substance chimique contenant des noyaux quadripolaires pour déterminer une caractéristique mesurable de la substance. Le procédé comprend l'irradiation de la substance avec de l'énergie radioélectrique d'une manière prédéterminée pour stimuler la RQN (résonance quadripolaire nucléaire) de certains noyaux quadripolaires dans la substance, puis la réception et le traitement d'un signal émis par la substance pour isoler un signal RQN de celle-ci, ensuite l'analyse du signal RQN pour obtenir une mesure de la caractéristique de la substance ; et la production d'un résultat indicatif de la mesure à des fins analytiques. L'invention concerne également des procédés spécifiques pour analyser une substance chimique lors de la production de celle-ci afin de déterminer une caractéristique de la substance indicatrice de la qualité de celle-ci, et pour rechercher des produits chimiques ainsi que des systèmes spécifiques.
Patent AU-2006308187-A1 (AU)
Title: Device for implanting and fastening heart valve prostheses
Inventor: FERRARI MARKUS
IPC: A61F2/95
Filed: 2006-10-17
Abstract: A device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent (10) with a prosthetic heart valve (11) at its proximal end is introducible into a patient's main artery. With the objective of optimizing such a device to the extent that the prosthetic heart valve (11) can be implanted into a patient in a minimally-invasive procedure, to ensure optimal positioning accuracy of the prosthesis (11) in the patient's ventricle, the device includes a self-expanding positioning stent (20) introducible into an aortic valve positioned within a patient. The positioning stent is configured separately from the heart valve stent (10) so that the two stents respectively interact in their expanded states such that the heart valve stent (10) is held by the positioning stent (20) in a position in the patient's aorta relative the heart valve predefinable by the positioning stent (20).
Patent AU-2006312793-A1 (AU)
Title: Double seat valve
Inventor: BURMESTER JENS
IPC: F16K1/44
Filed: 2006-02-18
Abstract: The invention relates to a double seat valve with cleanable seats, the valve including first and second closing elements (3, 4) and a leakage cavity (5). An intermediate seal (8) seals the closing elements (3, 4) in their opening and closing movements and in the open position against each other, is arranged in the second closing element (4). The second closing element (4) abuts in its closed position at a transition area (2e, 2e*) with a stop face (4e) arranged at a front face of a cylindrical lug (4*) and that directly adjacent to a first seat (2a, 2g), a central recess (4d) is provided in a front face of a second cylindrical lug (4*).
Patent AU-2006325850-A1 (AU)
Title: Method and apparatus for obtaining aliquot from liquid-based cytological sample
Inventor: WATTS HAL
IPC: B01L3/14
Filed: 2006-11-29
Abstract: An instrument for automated processing of sample vials are provided. The instrument causes an aliquot chamber within the vial to be filled with the fluid contained within the vial.
Patent WO-2008014555-A1 (WO)
Title: Procédé d'identification de cellules t cd4+ cd25+ activées contre un antigène et exprimant cd8
Inventor: HALL BRUCE MILNE
IPC: A61K39/00
Filed: 2007-08-02
Abstract: La présente invention concerne un procédé qui permet d'identifier des cellules T CD4+ CD25+ activées contre un antigène dans une population de cellules T, ledit procédé comprenant l'identification des cellules T CD4+ CD25+ qui expriment CD8. L'invention concerne également un procédé d'isolement de cellules T CD4+ CD25+ activées contre un antigène comprenant l'isolement des cellules T CD4+ CD25+ qui expriment CD8. L'invention concerne également un procédé permettant d'augmenter la tolérance envers un antigène chez un sujet par l'administration de cellules T CD4+ CD25+ qui expriment CD8.
Patent WO-2008014569-A1 (WO)
Title: Génération de vapeur
Inventor: BURNS ALAN ROBERT
IPC: F01K7/34
Filed: 2007-08-03
Abstract: L'invention concerne une centrale thermique à vapeur comprenant un appareil de génération de vapeur (11), une turbine (13) et un générateur électrique (15). La turbine de l'invention peut être adaptée pour être entraînée par un fluide de travail comprenant de la vapeur générée par l'appareil de génération de vapeur de l'invention. Cet appareil de génération de vapeur comprend une zone de combustion (22) et une première partie (33) et une seconde partie (35) associée à la zone de combustion pour recevoir des produits de combustion très chauds. Le générateur de vapeur comprend également une voie d'écoulement d'eau (165), une voie d'écoulement extérieure (163) destinée à un écoulement de gaz chaud, et une voie d'écoulement intérieure (161) destinée à un écoulement de gaz chaud. La voie d'écoulement extérieure est agencée autour de la voie d'écoulement d'eau, la voie d'écoulement d'eau étant agencée autour de la voix d'écoulement intérieure. La voie d'écoulement intérieure et la voie d'écoulement extérieure sont en relation d'échange thermique avec la voie d'écoulement d'eau.
Patent WO-2008064409-A1 (WO)
Title: A hole saw assembly including drive shafts supported by a rotatable annulus
Inventor: KEIGHTLEY KYM JOHN
IPC: B26D1/44
Filed: 2007-11-28
Abstract: A hole-saw assembly including a hole-saw having at one end a plurality of cutting teeth and at the other end a base having two holes therethrough. two shafts. The assembly includes a mandrel coaxially aligned with said hole-saw and including a body having two bores therethrough, and an annulus located on top of the body which is coaxially aligned with said mandrel and hole saw. The annulus includes two shafts co-axial with the mandrel bores, and is rotatable around its longitudinal axis from a first to a second position. In the first position the annulus shafts are aligned with the base holes allowing the shafts to be freely insertable and removable and in the second position the shafts are misaligned to lock the shafts to the base. In one embodiment the mandrel bores are shaped to accommodate rotation of the shafts, and in a further embodiment, the shafts are configures to rotate within circular mandrel bores. Such an arrangement allows the hole-saw and the mandrel to be easily and quickly mountable and demountable.
Patent AU-2007248303-A1 (AU)
Title: Bone anchor system utilizing a molded coupling member for coupling a bone anchor to a stabilization member and method therefor
Inventor: DEWEY JONATHAN M
IPC: A61B17/86
Filed: 2007-04-26
Abstract: A bone anchor system including a bone anchor having an integral head, a stabilization member, and a coupling member molded around the integral head of the bone anchor is provided for coupling the bone anchor to the stabilization member. The coupling member includes an interface to the stabilization member. Advantageously, the interface to the stabilization member is made of a deform able material to reduce surface stress concentration in the stabilization member. The interface of the coupling member may be integral to the coupling member, or the interface may be an interface piece that may be inserted into the coupling member. The integral head of a bone anchor may include a molded cap that is formed from a deformable material and configured to provide an interface to the stabilization member.
Patent AU-2008202531-A1 (AU)
Title: Oral dosage form comprising a therapeutic agent and an adverse-effect agent
Inventor: CARPANZO ANTHONY E
IPC: A61K9/30
Filed: 2008-06-06
Abstract: The present invention provides an oral dosage form comprising a first composition and a second composition. The first composition comprises an effective amount of a therapeutic agent and the second composition comprises an effective amount of an adverse-effect agent. The adverse-effect agent is covered with a coating that is substantially insoluble in the gastrointestinal tract. In one embodiment, the adverse-effect agent is coated with an outer base-soluble layer and an inner acid-soluble layer. The therapeutic agent can be uncoated or can be coated with a coating having an outer acid-soluble layer and an inner base-soluble layer. The dosage form discourages administration of the therapeutic agent by other than oral administration.
Patent AU-2008240341-A1 (AU)
Title: System and methods for performing percutaneous pedicle integrity assessments
Inventor: MARTINELLI SCOT
IPC: A61B17/56
Filed: 2008-10-31
Abstract: The present invention involves systems (20) and related methods for performing percutaneous pedicle integrity assessments involving the use of neurophysiology. The fundamental method steps for performing the percutaneous pedicle integrity assessments include (a) percutaneously introducing an insulation member to a pedicle target site; (b) establishing electrical communication between a stimulation element and an interior of a pedicle screw pilot hole; (c) applying a stimulation signal to the stimulation element; and (d) monitoring to assess whether nerves adjacent the pedicle are innervating as a result of the step of applying the stimulation signal to the stimulation element.
Patent AU-2008297981-A1 (AU)
Title: Electronic games apparatus
Inventor: GRAF JOHANN F
IPC: G07F17/32
Filed: 2008-09-05
Abstract: The present invention relates to a gaming machine and/or entertainment machine, in particular in the form of slot machines and/or gambling machines operable by coins and/or by monetary equivalents, having a plurality of screens for the presentation of information, in particular of game contents and/or of game information, which are directed toward a machine operating position, and having a control device for the control of the screens and/or for the control of game procedures. It is proposed to arrange a plurality of screens staggered behind one another and overlapping one another so that the viewing window onto at least one screen remains behind the actual screen surface of the screen with respect to format and/or size in order to accommodate a maximum number of screens in a compact arrangement, on the one hand, and in order not to be restricted to the desired field of view with respect to the formats of the screens to be used. Provision is made in accordance with the invention that at least one of the screens is arranged partly or fully hidden behind at least one further screen viewed from the machine operating position.
Patent AU-2009214388-A1 (AU)
Title: Louver rotating mechanism
Inventor: RUGGLES BRYAN K
IPC: E06B7/086
Filed: 2009-02-06
Abstract: A louver rotating mechanism for louvers of a sectional covering for architectural openings is adapted to rotate the louvers between an open position and a closed position. In the open position, the louvers are in generally parallel planes, and in the closed position, the louvers are generally in a common plane. The rotating mechanism includes a slot and gate system.
Patent AU-2009322836-A1 (AU)
Title: Soluble guanylate cyclase activators
Inventor: BROCKUNIER LINDA L
IPC: A61K31/522
Filed: 2009-11-16
Abstract: Compounds of Formula I are capable of modulating the body's production of cyclic guanosine monophosphate ("cGMP") and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of the Formula I, to their use for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of the Formula I.
Patent AU-2009340524-A1 (AU)
Title: Continuous single vessel butanol synthesis by fermentation
Inventor: BUTLER III EUGENE T
IPC: C12P7/16
Filed: 2009-02-26
Abstract: The present invention describes a method for producing butanol by fermentation of carbohydrates using mixed populations of acidogenic-phase cells and solventogenic-phase cells of in a solitary vessel. The present system as described does not require intermittent adjustment of pH or venting of headspace gases. The method provides a process for removal of the butanol product which does not irreversibly harm the cells and conditions are described where such cells may resume butanol synthesis in the same solitary vessel. The invention also describes compositions and biologically pure cultures which comprise the cells as disclosed.
Patent AU-2010209705-A1 (AU)
Title: DPP-IV inhibitors for treatment of diabetes in paediatric patients
Inventor: ULRIKE GRAEFE-MODY EVA
IPC: A61K31/519
Filed: 2010-01-29
Abstract: The present invention relates to the finding that certain DPP-4 inhibitors are particularly suitable for treating and/or preventing metabolic diseases, particularly diabetes, in paediatric patients.
Patent AU-2010227802-A1 (AU)
Title: Substituted spiro-amide compounds
Inventor: STEFAN SCHUNK
IPC: C07D401/14
Filed: 2010-03-23
Abstract: The present invention relates to substituted spiro-amide compounds, processes for the preparation thereof, medicaments containing these compounds and the use of substituted spiro-amide compounds for the preparation of medicaments.
Patent AU-2010241275-A1 (AU)
Title: Wire termination tool
Inventor: SLATER BRETT HOE
IPC: B25B33/00
Filed: 2010-11-05
Abstract: C:\NRPonbl\DCCKXM32X2674_LDOC-4/I l2O10 A tool for pushing a wire termination head holder towards a connector holder, the tool including a first arm and a second arm; a first assembly mechanically coupling the head 5 holder to the first arm, and a second assembly mechanically coupling the head holder to the second arm, wherein a relative movement of the first and second arms causes both of the first and second assemblies to push the head holder towards the connector holder. Figure 1
Patent AU-2010280706-A1 (AU)
Title: 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives as C-Met tyrosine kinase modulators
Inventor: FURET PASCAL
IPC: A61P35/00
Filed: 2010-08-06
Abstract: The invention relates to compounds of formula (I) and salts thereof, wherein the substituents are as defined in the specification, the application of a compound of formula (I) in a process for the treatment of the human or animal body, in particular with regard to C-Met tyrosine kinase mediated disease; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharamaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner; processes for the preparation of a compound of formula (I).
Patent AU-2010292172-A1 (AU)
Title: Extracellular targeted drug conjugates
Inventor: HUTCHINSON CHARLES B
IPC: A61K39/395
Filed: 2010-09-09
Abstract: The present invention relates to, inter alia, extracellular drug conjugates (EDC) in which an antibody or other targeting agent (e.g. a targeting moiety) is linked to a drug through a linker (e.g. a non-cleavable linker). These conjugates are useful in the treatment of disease and/or as a tool in the evaluation of biological systems.
Patent AU-2010293628-A1 (AU)
Title: Taste enhancing agent
Inventor: YAMAGUCHI SUSUMU
IPC: A23L27/20
Filed: 2010-08-16
Abstract: Disclosed is a taste enhancing agent for achieving sufficient saltiness or sweetness even in cases where the salt content or sugar content in food is reduced. Specifically disclosed is a taste enhancing agent which contains one or more substances selected from among linear aliphatic aldehydes having 3-10 carbon atoms and linear aliphatic alcohols having 4-10 carbon atoms as active ingredients. The amount of salt content or sugar content added to food can be reduced by adding the taste enhancing agent to the food.
Patent AU-2010295257-A1 (AU)
Title: A camera system
Inventor: DAHLHIELM FREDRICK STEFAN JARL
IPC: H04N7/18
Filed: 2010-09-21
Abstract: A furnace camera, including one or more image sensors for detecting one or more optical characteristics of a product resulting from a combustion process; and a burn-resistant body having an inner channel and an outer channel, said inner channel extending through said body between an inlet opening and an outlet opening, said inner channel having one or more optical elements positioned therein for adapting light received through said outlet opening for detection by said image sensors; wherein, said outer channel is adapted for directing a flow of fluid around said inner channel to minimise exposure of said inner channel to excessive heat when said system is in use, and said inner channel is adapted for directing a flow of gas to minimise exposure of said one or more optical elements to excessive heat when said system is in use.
Patent AU-2010302972-A1 (AU)
Title: Appliance for preparing a chocolate-based beverage
Inventor: AGON FABIEN LUDOVIC
IPC: A47J43/07
Filed: 2010-09-29
Abstract: A process for preparing a beverage comprises: providing a liquid carrier; supplying a flavouring ingredient to the liquid carrier; optionally heating the liquid carrier; and agitating the liquid carrier to promote dissolution and/or dispersion of the flavouring ingredient therein. The flavouring ingredient is supplied in the form of a self-sustaining body (2) to the liquid carrier, the self- sustaining body (2) having at least one surface (3) from which the flavouring ingredient is dissolved and/or dispersed into the liquid carrier. The liquid carrier is agitated in a controlled manner to circulate on this surface so as to achieve a controlled dissolution and/or dispersion of the flavouring ingredient into the liquid carrier.
Patent AU-2010303405-A1 (AU)
Title: System and method for heat rejection in a solar power collection system
Inventor: ORSELLO ROBERT
IPC: F24S10/30
Filed: 2010-10-07
Abstract: A heat rejection system for a solar power collector having an array of heliostat mirrors, the heat rejection system having a rail system supporting the array of heliostat mirrors, the rail system having a plurality of thermally conductive pipes, a reservoir positioned 'underground and connected to the rail system, a condenser connected to the thermally conductive pipes and the reservoir, and a coolant means circulating through the thermally conductive pipes, condenser and reservoir the heat rejection system operates as closed systems without the consumption of water and returns solar heat to the environment.
Patent AU-2010305869-A1 (AU)
Title: A clean-in-place device for a milk conveying system
Inventor: BOSMA EPKE
IPC: A01J7/02
Filed: 2010-10-12
Abstract: The invention relates to a clean-in-place device for a milk conveying system. The milk conveying system comprises at least two separate areas (A, B) with surfaces difficult to clean. The clean-in-place device comprises a steam source (24), steam passages (25, 26) extending between the steam source (24) and a respective outlet opening (25a, 26a) from which it is possible to supply steam to said areas (A, B) of the milk conveying system and control means (7, 27) adapted to control the supply of steam from the steam source (24) to said areas (A, B) of the milk conveying system.
Patent AU-2010310518-A1 (AU)
Title: mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
Inventor: CONN P JEFFREY
IPC: A01N43/56
Filed: 2010-10-22
Abstract: Pyrazole compounds useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.
Patent AU-2010319101-A1 (AU)
Title: Method for operating plant for producing mixed-gas hydrate
Inventor: TAKAHASHI MASAHIRO
IPC: F17C11/00
Filed: 2010-11-09
Abstract: The operation of a plant for producing a gas hydrate is stabilized by making the gas phases within downstream steps have the same equilibrium composition as the gas phase within a generation step. The gas phase within a mixed-gas hydrate generation step is circulated through the gas phases within downstream steps located downstream from the mixed-gas hydrate generation step, and the gas phases within the downstream steps are thereby made to have the same equilibrium composition as the gas phase within the generation step.
Patent AU-2010324538-A1 (AU)
Title: A rigging assembly for a dragline excavator
Inventor: BUHSE MURRAY
IPC: B66C1/12
Filed: 2010-11-26
Abstract: A rigging assembly for a dragline excavator where the rigging assembly has a first upper hoist link and a second upper hoist link. The rigging assembly also has an equalization member extending between the first upper hoist link and the second upper hoist link. The equalization member is formed from a flexible material.
Patent AU-2010350523-A1 (AU)
Title: Monitoring device and a method for wireless data and power transmission in a monitoring device
Inventor: ANDERSEN HENNING HAUGAARD
IPC: H04B5/00
Filed: 2010-04-06
Abstract: In a monitoring device including a reader and a data carrier, the data carrier includes a receiver coil (201, 409), a resonator capacitor (202, 402), rectifier means (203, 403), a modulation capacitor (206, 406), an energy- storage capacitor (204, 404), three modulation switches (209, 210, 211) and data processing means. The modulation capacitor (206, 406), the energy storage capacitor (204, 404), the data processing means and the three modulation switches (209, 210, 211) are arranged such that, in a first configuration, the modulation capacitor (206, 406) and the energy storage capacitor (204, 404) are coupled in parallel and, in a second configuration, the modulation capacitor (206, 406) and the energy storage capacitor (204, 404) are coupled in series. The invention further provides a method of operating a data carrier in such a monitoring device.