baber/WOPTO huggingface dataset:
Patent CA-2370286-A1 (CA)
Title: A ligand of the protein "beacon"
Inventor: WALDER KEN
IPC: C07K14/47
Filed: 2000-04-19
Abstract: The present invention relates generally to a ligand for a protein associated with modulating obesity, diabetes and metabolic energy levels in animals and humans and to genetic sequences encoding the ligand. More particularly, the present invention is directed to a ligand of the protein "beacon" and its homologues. The identification of the ligand molecule permits the development of a range of therapeutic and diagnostic protocols for obesity, diabetes and energy imbalance.
Patent CA-2370493-A1 (CA)
Title: Peptides and assays for the diagnosis of lyme disease and compositions useful for the prevention thereof
Inventor: LIANG FANG TING
IPC: C12N15/31
Filed: 2000-04-25
Abstract: A peptide consisting of an invariable 26-amino-acid-long region, named IR6, which is antigenically conserved among strains and species of the B. burgdorferi sensu lato complex, and immunodominant in both human and nonhuman primate hosts is described. This peptide is characterized by the sequence MKKDDQIAAAMVLRGMAKDGQFALKD [SEQ ID NO: 1]. This peptide is useful for rapid and specific diagnosis of Lyme disease, as are proteins containing this peptide and nucleic acid sequences encoding this peptide and these proteins. Also provided is a novel ELISA, which is characterized by high sensitivity and specificity.
Patent CA-2373240-A1 (CA)
Inventor: CHANDLER JOSEPH
IPC: B21F15/06
Filed: 2001-03-12
Abstract: An apparatus and method are provided for applying clips (13) to mattress spring assemblies (12) via operating or positioning members (28) that position the innerspring coils (16) relative to the borderwires (14) with the end turns (20) of the coils (16) disposed inwardly relative to adjacent borderwires (14) in a predetermined clipping orientation. Improperly positioned innersprings (16) have their end coils (20) shifted past the borderwires (14) as they are advanced downstream to be clipped. The positioning members (28) use the progression of the spring assemblies (12) as they move downstream in the automatic clipping machine to properly position the innerspring coils (16) relative to the borderwires (14). At least one positioning member upstream from the clip applicator tool causes the end turns of the coils to progressively shift into the position necessary for proper clipping of the end turns to the borderwires. The positioning member does not have to be cycled between operative and inoperative positions for each clip that is applied
Patent CA-2373578-A1 (CA)
Title: .beta.3, agonists and uses thereof
Inventor: PAIGHT ERNEST SIDNEY JR
IPC: A61K31/496
Filed: 2002-02-27
Abstract: Sulfamide compounds having formula (I) are described as well as their use in the treatment of diseases dependent on the signaling pathways associated with .beta.-adrenergic receptors, such as obesity, diabetes, hypertension, gastrointestinal hypo- or hyper-motility and cardiovascular diseases.
Patent CA-2377125-A1 (CA)
Inventor: GAEBLER DAVID M
IPC: A23L19/00
Filed: 2002-03-18
Abstract: Vegetable sausage analogues are provided which have texture and flavor delivery components dispersed within a set-up matrix formed from a composition including powdered vegetable protein. Included is a structured filamentous protein component which mimics connective tissue proteins of meat products. Other components can include thermally preformed textured proteinaceous gel phase components to mimic particles of meat protein. Further includable components are thermally structured starch carbohydrate gel crumble components which enhance flavor delivery when the sausage product is chewed.
Patent CA-2379136-A1 (CA)
Inventor: WEILACHER HERMANN
IPC: G06Q20/00
Filed: 2000-07-11
Abstract: L'invention concerne un système pour effectuer des transactions, présentant des terminaux permettant, dans son principe, d'effectuer une pluralité de différentes transactions. A cet effet, les terminaux (10, 11) sont connectés, via un réseau de terminaux (30), avec au moins un calculateur nodal (40, 41), au moyen desquels ils peuvent être installés en vue d'effectuer une transaction. La particularité d'effectuer une autre transaction jusqu'à présent non réalisée est dès lors possible, à tout moment, sans dispositions spéciales d'agencement. A cet effet, l'invention est caractérisée en ce qu'il est prévu un terminal (10, 11) qui, en réponse à un signal de déclenchement en relation avec l'autre transaction, fournit, à partir d'un calculateur nodal (40, 41), des données générant la fonctionnalité requise pour effectuer l'autre transaction. La transaction s'effectue alors en interaction entre un terminal (10, 11) et un calculateur nodal (40, 41).
Patent CA-2379323-A1 (CA)
Inventor: CLAGETT JAMES
IPC: A61K38/07
Filed: 2000-07-14
Abstract: A method for downregulating IgE levels is described. The method involves administering to a patient an IgE downregulating effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
Patent CA-2380490-A1 (CA)
Title: Method of producing antimicrobial synthetic bodies with improved long-term behavior
Inventor: GUGGENBICHLER J PETER
IPC: C08K3/08
Filed: 2000-07-28
Abstract: The invention relates to a method of producing antimicrobial synthetic bodies, including shaping a preproduct. The inventive method is characterized in that at least one component of the preproduct is treated with a metal colloid before shaping.
Patent CA-2382691-A1 (CA)
Title: Oxazinoquinolones useful for the treatment of viral infections
Inventor: TURNER STEVEN RONALD
IPC: A61K31/5383
Filed: 2000-09-28
Abstract: The present invention provides a compound of formula (I). Thesecompounds are useful as antiviral agents, in particular, as agents against viruses of the herpes family.
Patent CA-2385191-A1 (CA)
Title: Method, apparatus, and system for signal prediction
Inventor: GAAL PETER
IPC: H04J3/00
Filed: 2001-08-07
Abstract: An apparatus, method, and system for predicting subframes of GPS signals. Th e apparatus includes a processor capable of determining whether a subframe is an almanac subframe, setting a timehead and adding it to a TOW, setting a TLM message based on a value of the TOW, generating a CRC for a predicted subframe, and a memory for storing the predicted subframe. The memory may va ry in size based on the number of predicted subframes. The processor is further  capable of determining whether the value of the TOW is less than the number of seconds in a week, calculating a position of the predicted subframe in the memory, and setting a valid flag.
Patent CA-2386409-A1 (CA)
Title: Device for measuring the temperatures of axles or bearings for locating hot-boxes or overheated brakes in rolling stock
Inventor: NAYER WOLFGANG
IPC: B61K9/06
Filed: 2000-10-09
Abstract: The invention relates to a device for measuring the temperatures of axles or bearings for locating hot-boxes or over-heated brakes in rolling stock. The infrared rays of the measuring points are guided over an oscillating mirror (9) and onto an infrared receiver (8). Sent infrared rays are detected in the scanning level which is defined by the oscillation of the oscillating mirror (9) and crosswise in relation to the longitudinal direction of the rails. At least two deviation mirrors (1, 2) are arranged in the scanning level and at a distance (a) from each other crosswise in relation to the longitudinal direction of the rails. The deviated infrared rays of the deviation mirrors (1, 2) are detected in chronological sequence and according to the oscillation of the oscillating mirror (9).
Patent CA-2387352-A1 (CA)
Title: Core body locking device of a core drill, and core body for use therein
Inventor: MIYANAGA MASAAKI
IPC: B23B51/04
Filed: 2000-03-09
Abstract: It is an object to provide a locking device of a core drill which automatically locks a core body when the core body is attached to a base body, the coupling relation between the base body and the core body being fixed unless an unlocking operation is performed by an act of worker, wherein in the core drill including the base body and the core body which are connected to each other by the engagement of an engagement projection with an engagement concave portion, an engagement pawl of the locking device is disposed on the base body, and under the condition that the engagement projection engages the engagement concave portion, the engagement pawl being biased by a compression spring is caused to descend to a back portion of the engagement projection to fix the engagement projection within the engagement concave portion thereby locking the core body.
Patent CA-2387422-A1 (CA)
Title: Ventilateur tangentiel dote d'un element d'aspiration ferme, et dispositif de separation d'aspiration de flux uni
Inventor: KERTESZ ANDRAS
IPC: B07B7/086
Filed: 2000-10-11
Abstract: L'invention concerne un ventilateur tangentiel qui peut également fonctionner en mode d'aspiration, notamment dans des conduits d'air possédant une largeur importante, afin de produire un flux uni d'air réglable. Cette invention concerne aussi un dispositif de séparation d'aspiration de flux uni qui est approprié à largeur importante d'une quantité d'air contenant une fraction solide en cas d'aspiration régulée et de séparation de la fraction solide du côté de l'entrée et sous certaines formes de sa construction, le flux d'air étant destinée à circuler. Le dispositif de séparation d'aspiration de flux uni est équipé d'un dispositif (8) de séparation centrifuge courbé, d'une sortie de fraction (9, 10, 11). La caractéristique du dispositif de cette invention consiste en ce qu'il comprend un rotor tangentiel (2), un logement (1) construit comme une gaine pneumatique (13) et un élément d'aspiration fermé (3) fixé sur le bord interne du dispositif de séparation centrifuge (12).
Patent CA-2388424-A1 (CA)
Inventor: GIDWANI JAWAHAR M
IPC: B01J19/08
Filed: 2000-10-18
Abstract: L'invention concerne un procédé et un appareil servant à stimuler des réactions chimiques sur une surface (116) de catalyseur à l'aide d'électricité, et le processus inverse de conversion d'énergie libérée par des réactions chimiques en électricité. Un émetteur réversible (102) génère des électrons qui sont injectés dans des réactifs sur le surface (116) du catalyseur, ce qui excite chimiquement des résonances réactives de vibrations. Des électrons chauds créés dans la zone de l'émetteur d'une jonction de semi-conducteur (110) sont diffusés au niveau de la zone du collecteur contigu et à la surface (116) du catalyseur. Des groupes du catalyseur ou des films liés à la surface du collecteur transfèrent les électrons chauds vers ou à partir de la surface (116) du catalyseur ayant absorbé des réactifs. La dimension du collecteur (104) de catalyseur est inférieure à celle de la voie libre du dispositif d'énergie d'électrons chauds. Les électrons chauds excitent des vibrations de réactifs avant de thermalizer le réseau moléculaire du substrat, ce qui entraîne une accélération des réactions. Les électrons chauds sont aussi générés par les réactions similaires à la surface du catalyseur. Le procédé et l'appareil sont réversibles et peuvent fonctionner comme un générateur électrique au moyen des réactions chimiques.
Patent CA-2392665-A1 (CA)
Title: Method for producing aluminum hydroxide
Inventor: KATO HISAKATSU
IPC: C01F7/02
Filed: 2002-07-08
Abstract: An aluminum hydroxide having high purity with high brightness and a method for producing such an aluminum hydroxide are provided . The aluminum hydroxide may be produced by a method which comprises the steps of mixing a crude aluminum hydroxide with an alkaline solution to obtain a mixture thereof ; heating the mixture to obtain a slurry in which a solid of aluminum hydroxide is present in an amount of from about 10% by weight to about 90% by weight based on the crude aluminum hydroxide to be used for the mixing; cooling the slurry to precipitate an aluminum hydroxide; and separating the resulting aluminum hydroxide from the slurry.
Patent CA-2394538-A1 (CA)
Inventor: WEBSTER KEVIN R
IPC: A61P25/28
Filed: 2000-12-06
Abstract: L'invention concerne des composés de la formule générale (I) et des sels pharmaceutiquement acceptables de ces composés, dans lesquelles R¿1? et R¿2? représentent indépendamment un hydrogène, un fluor ou un alkyle, R¿3? représente un aryle ou un hétéroaryle, R¿4? a plusieurs significations, R¿5? représente un hydrogène ou un alkyle, m représente un nombre entier compris entre 0 et 2, et n représente un nombre entier compris entre 1 et 3. Les composés de la formule générale (I) sont des inhibiteurs de la protéine kinase et sont utiles dans le traitement et la prévention de maladies prolifératives comme le cancer, les inflammations et l'arthrite. Ces composés peuvent également s'avérer utiles dans le traitement de maladies neurodégénératives comme les maladies d'Alzheimer, les maladies cardio-vasculaires, les infections virales et les mycoses.
Patent CA-2395138-A1 (CA)
Inventor: LITTLE JULIE
IPC: D06L4/40
Filed: 2000-12-08
Abstract: There is provided a method of delivering a benefit agent to a selected area of a fabric for exerting a predetermined activity, wherein the area is pre-treated with a multi-specific binding molecule which has a high binding affinity to said area through one specificity and is capable of binding to said benefit agent through another specificity, followed by contacting said pre-treated area with said benefit agent, to enhance said pre-determined activity to said area. Preferably, the binding molecule is an antibody or fragment thereof, or a fusion protein comprising a cellulose binding domain and a domain having a high binding affinity to another ligand which is directed to said benefit agent. The method is useful for stain removal, perfume delivery, and treating collars and cuffs for wear. Also provided is a device for use in this method, which is a dispenser capable of depositing a multi-specific binding molecule to a selected area of a fabric through a semi-solid wax or soap-stick, spray, aerosol, impregnated brush, gel, or foam, and the like.
Patent CA-2396996-A1 (CA)
Title: Genetically modified fibroblast cell
Inventor: SZABOWSKI AXEL
IPC: A61K39/395
Filed: 2001-01-12
Abstract: Disclosed are genetically modified fibroblast cells having the following characteristics: (a) A gene of the genome thereof is inactivated and/or a component of the signal transduction path is modified by means of a sequence of a modified AP-1 activity, said gene coding for a subunit of the transcription factor AP-1 and said component acting on the transcription factor AP-1. (b) The inventive fibroblast cell contains the gene of (a) in an expression vector and functionally combined with a promoter and in such a form that the active subunit is only expressed after induction of the promoter or the subunit that is coded by the gene is present in the inactive form and can be activated. The invention also relates to a method using the inventive fibroblast cell for identifying a compound that can promote, inhibit or modify the AP-1 dependent differentiation and/or proliferation of keratinocytes or for identifying a gene that takes part in the AP-1 dependent differentiation and/or proliferation of keratinocytes. The invention further relates to the use of the test compound or gene that has been identified by means of the inventive method, for treating or diagnosing diseases which are associated to a disturbed proliferation and/or differentiation of keratinocytes.
Patent CA-2399104-A1 (CA)
Inventor: CROOK DALE J
IPC: F24F13/06
Filed: 2001-02-05
Abstract: L'invention concerne un ensemble gaine (2) conçu pour soutenir un conduit flexible (4), qui comprend un cadre (6) doté d'une première et d'une deuxième section (10 a,b). Les sections du cadre sont fixées l'une à l'autre par des sous-ensembles de fixation (8). L'ensemble gaine reçoit des conduits flexibles dans diverses configurations angulaires et droites. Le cadre peut être constitué de différentes matières appropriées et d'une construction squelette ou d'une construction à extérieur solide. L'ensemble gaine est adapté à différentes installations dans des systèmes de diffusion d'air ou des systèmes de chauffage, de ventilation et de climatisation.
Patent CA-2403191-A1 (CA)
Title: Fault location on a telecommunications network
Inventor: LOGAN HILARY PAUL
IPC: H04M3/30
Filed: 2001-03-05
Abstract: A fault location system for a telecommuni-cations network including a local exchange or switch, a node such as a primary connection point and a plurality of line terminations that the customer includes probability calcula-tion to establish the location of a fault; measuring from the exchange. Historical non-faulty reference values of capac-itance are compiled for each line passing through the node providing a measure of the distance of each line. A  low-est valid capacitance value provides an estimate of the ref-erence capacitance between the exchange and the node. A  histogram is compiled of historic fault values and a new fault is compared against the histogram to establish the probabil-ity of it being a fault at the node or elsewhere. As a result the reference capacitance can be obtained without the need for an engineer at the node, and the likely location of a fault can be pinpointed with greater accuracy.
Patent CA-2404283-A1 (CA)
Title: Measurement of pipe joint misalignment at weld interface
Inventor: SIEBERT MARTIN ANTON
IPC: B23K31/02
Filed: 2001-03-19
Abstract: A method of monitoring the alignment of pipes to be welded end to end involves supporting a reference bar extending generally parallel to, and external of, the pipes so as to span a weld position of which the ends of two pipes are to be welded, performing measurements of perpendicular distance between the bar and each pipe at two predetermined distances from the end of each pipe, determining the thickness of the walls of the pipes, determining the slope of the exterior of each pipe with respect to the reference bar, calculating from the slopes the difference between the distances from the bar to the outer surface of each of the two pipes to the weld position, so as to provide a measure of the misalignment of the outer surface of the pipes at the weld position, differencing the wall thicknesses of the pipes to provide a wall thickness difference, and subtracting the wall thickness difference from the misalignment of the external walls of the pipe to determine the misalignment of the inner surfaces of the pipes at the weld position. It is preferred to measure pipe thicknesses at multiple distances from the end of each pipe and average the results to obtain average thicknesses for the two pipes. The misalignment measurements will usually be repeated at successive points around the periphery of the pipes.
Patent CA-2405106-A1 (CA)
Title: Collecteur a commande mecanique pour bibliotheque informatique de donnees
Inventor: EVANSON DANIEL R
IPC: G11B15/68
Filed: 2001-04-05
Abstract: Cette invention a trait à un appareil permettant de recueillir et de placer des supports contenus dans des magasins ainsi que dans des unités d'entraînement d'une bibliothèque informatique de données, sans mécanismes de commande électrique ou de commande mécanique distincte permettant de saisir et de relâcher le système de saisie de supports. Cet appareil comporte un chariot (30) pouvant effectuer un mouvement de va-et-vient relativement aux supports (M), ces supports se trouvant dans les magasins et les unités d'entraînement ainsi qu'au moins un élément de saisie (40) monté pivotant sur le chariot par un point de pivotement (50) et possédant une pièce de verrouillage conçue pour venir au contact du système de saisie de supports. Cet élément de saisie peut passer d'une position ouverte, dans laquelle la pièce de verrouillage est éloignée du système de saisie, à une position fermée, dans laquelle la pièce de verrouillage entre en contact avec le système de saisie. Cet appareil est également pourvu d'un ressort dont une première extrémité est rattachée au chariot et dont l'autre extrémité est rattachée à l'élément de saisie. Il est possible d'orienter le ressort de manière qu'il pousse l'élément de saisie vers les supports ou de manière à l'éloigner de ces supports. Le déplacement de l'élément de saisie entre la position ouverte et la position fermée ainsi qu'entre la position fermée et la position ouverte est le fait d'un mouvement de cet élément contre les supports que contiennent les magasins et les unités d'entraînement et ce, sans intervention d'un mécanisme de commande électrique ou de commande mécanique distincte coopérant avec l'élément de saisie.
Patent CA-2407216-A1 (CA)
Inventor: PADGET DAVID B
IPC: A61B19/08
Filed: 2002-10-09
Abstract: A surgical drape manufactured or fabricated from a polymeric film having a low glare finish and a predetermined coloration for reducing the luminous intensity of light reflected from the surface thereof is provided.  Such surgical drape thereby minimizes reflectivity therefrom, and thus eye strain and fatigue.  The subject invention includes the use of colorants, dyes, pigments, etc. to form translucent polymeric surgical drapes that absorb a selected range of wavelengths from surface reflected light. More particularly, the use of coloring agents in combination with a textured surface yield a surgical drape possessing reduced luminance and glare, thereby mitigating eye strain and fatigue. The preferred range of reflected light, in order of preference, is 625-700 nm, 520-560 nm, 450-520 nm, 400-450 nm, 600-625 nm, and 560-600 nm.
Patent CA-2407778-A1 (CA)
Title: Coating apparatus and method of use
Inventor: LOHKAMP MARK R
IPC: A23P1/08
Filed: 2001-05-10
Abstract: A device for coating materials is provided. The device includes two opposing discs (12a, 6) connected by a central hub (20). Each disc includes an inwardly extending flange about its perimeter. The central hub has an exterior surface defining a v-shaped surface (22). When assembled in a coating apparatus, a fluid material, such as batter, may be dispensed toward the exterior surface of the hub while the disc is spinning. The resulting spray of fluid may be used to coat material effectively, while minimizing waste.
Patent CA-2409833-A1 (CA)
Inventor: BUCHANAN KRIS S
IPC: G01N35/10
Filed: 2001-05-18
Abstract: Material transfer technology that apportions discrete amounts of material (1 ) and introduces the apportioned material into a selectably engaged flow path (17) to provide a plurality of separate materials within a continuous fluid stream that can be delivered to numerous material differentiation technologi es (3) for analysis.
Patent CA-2415569-A1 (CA)
Inventor: HATA KATSURA
IPC: A61K31/437
Filed: 2001-07-06
Abstract: L'invention concerne la construction d'un système de rapporteurs reflétant le processus de transport d'une protéine d'ancrage GPI vers la paroi cellulaire et la découverte d'un composé inhibant ce processus. En outre, l'invention porte sur l'identification d'un gène conférant une tolérance au composé susmentionné et la mise au point d'un procédé de criblage d'un composé inhibant l'activité de la protéine codée par ce gène. Ainsi, ce nouveau composé permet d'établir que des agents antifongiques dépendant d'un nouveau mécanisme, où le processus de transport de la protéine d'ancrage GPI vers la paroi cellulaire est inhibée, sont disponibles.
Patent CA-2416720-A1 (CA)
Inventor: NAGANO SHIGENORI
IPC: G07D7/12
Filed: 2002-02-18
Abstract: A card true/false decision apparatus comprises a measuring light projection system (23) for projecting a measuring beam P from a predetermined direction  to a hologram (2) provided at a predetermined position on a card (1), a photodetector element (24b) for receiving the reflected/diffracted light R1,  R2, and R3 of the measuring beam P reflected by the hologram (2), averaging means (25) for changing the radiation position of the measuring beam P on th e hologram 2 so as to average photodetector signals corresponding to the light  quantity distribution on the photodetector element (24b), and decision means  (26) for comparing the output of the averaging means with an allowance value  so as to determine whether the card is true or false.