baber/WOPTO huggingface dataset:
Patent NZ-562842-A (NZ)
Title: Anaerobic purification device
Inventor: VELLINGA SJOERD HUBERTUS JOZEF
IPC: C02F3/28
Filed: 2005-06-10
Abstract: An anaerobic purification device for purification of influent such as wastewater, comprises a reactor tank 14, an inlet 12 at the bottom of the tank 14 for introducing influent into the tank 14, a water collector 11 like an overflow gutter for collecting purified water, a gas collecting system 4 placed at a level below the water collector 11 for collecting gas from the fluid contained in the tank 14, a gas-liquid separation device, a riser 5 for passing liquid lifted by gas collected in the gas collecting system into the separation device 6, and a downer 8 for returning liquid and sludge from the separation device 16 into the lower tank section . The water collector 11 is provided in the upper section of the tank 14 and defines a liquid surface 21 in the tank 14. A head pressure of at least about 1.4 m water column (about 0.14 bar) is present in the downer 8 at the level of the liquid surface 21. The riser 5 extends upwards for a height H3 of at least 1.2 m from the liquid surface 21. The device provides improved fluidization at the bottom of the reactor tank 14 and allows the height of the reactor tank 14 to be increased. .
Patent NZ-564317-A (NZ)
Title: Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors
Inventor: WANG BIN
IPC: A61K31/506
Filed: 2006-05-12
Abstract: Disclosed are ten compounds of general formula (I), whose specific formulas are disclosed in the specification. Also described are more compounds of formula (I), wherein the substituents are as defined in the specification. The compounds are useful as Trk kinase inhibitors, and for treating diseases such as cancer.
Patent NZ-570235-A (NZ)
Title: Octahydro-pyrrolo[3,4-b]pyrrole derivatives and their use as histamine-3 receptor ligands
Inventor: COWART MARLON D
IPC: A61K31/501
Filed: 2007-02-16
Abstract: Disclosed are 1-phenyl-pyrrolo[3,4-b]pyrrole derivatives as represented by the general formula (I), wherein R1 is alkyl, cycloalkyl, or (cycloalkyl)methyl; R2a-R2f each are independently hydrogen, methyl, or fluoromethyl; R3a-R3d are each independently hydrogen, alkyl, fluoroalkyl, fluoroalkoxy, alkoxy, thioalkoxy, halogen, or nitrile; L1 is a bond, oxygen, sulfur, carbonyl, alkylene, alkylcarbonyl, alkylamino, -C(=N-Oalkyl)-, or NR4; L2 is a bond, oxygen, sulphur, carbonyl, alkylene, alkylcarbonyl, alkylamino, -C(=N-Oalkyl)-, NR5, -C(=O)NR5-, or -NR5C(=O)-; Cy1 is aryl, cycloalkyl, cycloalkenyl, heteroaryl, or heterocycle; Cy2 is aryl, cycloalkyl, cycloalkenyl, heteroaryl or heterocycle, wherein the heteroaryl or heterocycle moiety has 1, 2, or 3 heteroatoms selected from nitrogen, oxygen, and sulfur, provided that at least one heteroatom is nitrogen; and wherein the other substituents are as defined herein. Of particular importance are the compounds 2-{ 4'-[(3aR,6aR)-5- methylhexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl]-1,1'-biphenyl-4-yl} pyridazin-3(2H)-one, 2-(5-{ 4-[(3aR,6aR)-5-methylhexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl]phenyl} pyridin-2-yl)pyridazin-3(2H)-one and 2-(6-{ 4-[(3aR,6aR)-5-methylhexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl]phenyl} pyridin-3-yl)pyridazin-3(2H)-one. Further disclosed is a harmaceutical composition which comprises a compound as defined above and a pharmaceutically acceptable carrier.
Patent NZ-571623-A (NZ)
Title: Folding container with elastically suspended floor
Inventor: HADAR NIR
IPC: B65D19/00
Filed: 2007-04-10
Abstract: Disclosed is a container which includes a set of four folding walls, each of which is deployable between an upright container-forming position and a folded position; a floor located within and vertically displaceable relative to the walls; and a suspension arrangement including four elastic suspension elements which suspend the floor relative to the walls. When the floor is loaded it assumes a lowered position, and when a portion of the load is removed, the suspension arrangement raises the floor towards a raised position.
Patent NZ-571827-A (NZ)
Title: LED pool and spa light
Inventor: NETZEL ROBERT J
IPC: H05B44/00
Filed: 2006-10-26
Abstract: A lighting fixture (300) comprises a housing (302) having an interior cavity (303) and an opening (320) ; a transparent cover (330) attached to the housing and covering the opening and a heat sink (322) including a first mounting portion (324) and a second mounting portion (326). The first mounting portion is attached to the housing within the interior cavity and the second mounting portion has a first side and a second side opposite the first side. The lighting fixture further has a first circuit board (312) mounted to the first side of the second mounting portion and a lighting assembly including an LED light source. The LED light source includes a plurality of LEDs (314) mounted to the first circuit board. The lighting fixture also has a second circuit board (313) mounted to the second side of the second mounting portion. The second circuit board includes at least of portion of a control circuit (100). The control circuit is operatively connected to the LED light source for selectively providing power to each of the plurality of LEDs. The lighting fixture operates while the housing is submerged in water so that heat generated by the LEDs and the control circuit is conducted to the heat sink. The heat sink conducts the heat to the housing and the housing conducts the heat to the water. (62) Divided Out of 550803
Patent NZ-574164-A (NZ)
Title: Novel compound having affinity for amyloid
Inventor: TANIFUJI SHIGEYUKI
IPC: C07D471/04
Filed: 2007-06-21
Abstract: Disclosed is a compound of formula (1) where the substituents are as disclosed in the description. Example of compound of formula (1) are: 2-[4'-(3"[18F]fluoropropoxy)phenyl]-6-methoxyimidazo[1,2-a] pyridine and 6-methoxy-2-[4'-(3"-p-toluenesulfonyloxypropoxy) phenyl] imidazo [1,2-a] pyridine. Also disclosed is a low-toxic diagnostic agent for Alzheimer's disease comprising a compound of formula (1); a pharmaceutical composition comprising a compound of formula (1) and the use of a compound of formula (1) for the preparation of a composition or agent.
Patent NZ-577548-A (NZ)
Title: Cancer biomarkers
Inventor: PANDHA HARDEV
IPC: G01N33/574
Filed: 2007-12-19
Abstract: Provided is a method of diagnosing or monitoring the progression of prostate cancer, comprising detecting and/or quantifying at least one homeodomain containing transcription factor or a fragment thereof in at least two samples of body fluid from a test subject, wherein the homeodomain containing transcription factor is an EN-2 peptide comprising a specified sequence or it variant with at least 80% sequence identity, and wherein the at least two body fluid samples previously obtained at different time points to determine the diagnosis or progression of prostate cancer and wherein an increase in the level of the at least one homeodomain containing transcription factor, or a fragment thereof, being found in the body fluid sample is indicative that the disease is either progressing or has initiated.
Patent NZ-580820-A (NZ)
Title: Recombinant antibody production in avian embryonic stem cells
Inventor: MEHTALI MAJID
IPC: A61K38/00
Filed: 2008-05-21
Abstract: Disclosed is a method for producing an antibody molecule, which has increased Fc-mediated cellular toxicity compared to the antibody produced in a hybridoma or wild-type CHO cell line, in avian cells. The method comprises; (a) Preparing avian cells by transfection with an expression vector expressing the antibody molecule; (b) Culturing the avian cells under suitable condition and in suitable culture medium (c) Harvesting the antibody molecule from the avian cells, the culture medium or both. The avian cells are from a continuous, adherent or non-adherent cell line, obtained by in vitro culture and expansion of avian Embryonic Stem (ES) cells, followed by the progressive withdrawal of animal serum, feeder cells and exogenous growth factors from the cell culture medium. The avian cells have the ability to proliferate in a culture medium in the absence of animal serum, feeder cells and exogenous growth factors.
Patent NZ-590433-A (NZ)
Title: Secure email system using alias addresses and encryption
Inventor: RODRIGUEZ RICARDO J
IPC: H04L12/58
Filed: 2009-06-17
Abstract: 590433 Disclosed is a secure e-mail messaging system (10). The system (10) includes an e-mail relay server (12) coupled to a secure client (14) that is configured on a secure domain (16) and an external client (20) that is configured on an external domain (22). The e-mail relay server (12) has a memory for storage of an actual address of the secure client (14), a first certificate associated with the actual address, an alias address associated with the actual address, and a second certificate associated with the alias address. The actual address includes domain structure information of the secure domain (16). The first certificate includes a public key of the actual address and a private key of the alias address, and the second certificate includes a public key of the alias address and a private key of the external client. The e-mail relay server (12) is operable to receive an e-mail message comprising the alias address as a recipient from the external client (20). The alias address comprises a local part and domain structure information of the external domain (22). Both the local part and the domain structure information of the external domain (22) of the alias address are devoid of the domain structure information of the secure domain (16). The e-mail message is encrypted according to the public key of the alias address and the email message is encrypted according to the private key of the external client (20) for a first signature. The public key of the alias address and the private key of the external client (20) are extracted from the second certificate previously issued to the external client (20). The e-mail relay server (12) is also operable to decrypt the e-mail message according to the second certificate. This decrypting includes verifying whether the email message has the first signature of the external client (20). Verifying includes decrypting the e-mail message according to a public key of the external client (20) accessible to the e-mail relay server (12). The e-mail relay server (12) is also operable to replace the alias address with the actual address of the secure client (14) as the recipient to form a modified e-mail message and encrypt the modified e-mail message according to the public key of the actual address and encrypt the modified email message according to the private key of the alias address for a second signature. The public key of the actual address and the private key of the alias address are extracted from the first certificate. The e-mail relay server (12) is further operable to transmit the modified e-mail message to the secure client (14) as encrypted according to the public key of the actual address and signed according to the private key of the alias address.
Patent NZ-596014-A (NZ)
Title: Dihydroorotate - dehydrogenase inhibitors as virostatic compounds
Inventor: VITT DANIEL
IPC: A61K31/196
Filed: 2010-05-04
Abstract: Disclosed herein is the use of a dihydroorotate-dehydrogenase inhibitor of general formula (I) or a physiologically functional derivative, wherein the substituents are as defined within the specification, in the manufacture of a medicament for the treatment or amelioration of a disease or medical condition caused by a viral infection by a virus selected from the group comprising Human Immunodeficiency Virus (HIV), Hepatitis C Virus (HCV), Hepatitis B Virus (HBV), and Influenza, BK-Polyomavirus (BKV), Human Cytomegaly Virus (HCMV), Rift Valley Fever *Virus (RVFV), Norovirus (NV), Lassa Virus (LV), Ebolavirus (EBOV), West Nile Virus (WNV), Dengue Virus (DV), Human Respiratory Syncytial Virus (RSV), Yellow fever virus (YFV); wherein in said physiologically functional derivative one or more of the chemical groups of the compound of the general formula (I) are modified by a modification selected from the group comprising ester, phosphate or sulfate derivatives of hydroxyl groups; ester or amide derivatives of carboxylic groups; and imine, amide or urea derivatives of amino groups, or a pharmacologically tolerable salt thereof.
Patent NZ-601500-A (NZ)
Title: Hydrocarbon gas processing
Inventor: HUDSON HANK M
IPC: C07B63/00
Filed: 2010-12-29
Abstract: A process and an apparatus are disclosed for the recovery of ethane, ethylene, propane, propylene, and heavier hydrocarbon components from a hydrocarbon gas stream The stream is cooled and divided into first and second streams The first stream is further cooled to condense substantially all of it and is thereafter expanded to the fractionation tower pressure and supplied to the fractionation tower at an upper mid-column feed position The second stream is expanded to the tower pressure and supplied to the column at a mid-column feed position A distillation vapor stream is withdrawn from the column above the feed point of the first stream, combined with a portion of the tower overhead vapor stream, compressed to higher pressure, and directed into heat exchange relation with the remaining tower overhead vapor stream to cool the compressed combined vapor stream and condense at least a part of it, forming a condensed stream
Patent NZ-602071-A (NZ)
Title: Improvements in and relating to paperboard
Inventor: ROGERS JASON PAUL
IPC: G09F7/00
Filed: 2012-08-28
Abstract: A closed cell coreboard base 2 for a sign 3 having a display surface formed from a planar sheet of closed cell coreboard, where the base 2, in use, spans a distance X along an axis for and aft of the plane of the display surface, and wherein the base 2 has a slot, dimensioned to frictionally receive, front and rear planar surfaces of the display surface, and where the axis of the slot Y is substantially perpendicular to the for and aft axis. The distance X and effective depth of the slot are both sufficient to maintain the display surface in a substantially vertical orientation.
Patent NZ-605503-A (NZ)
Title: Catalyst for the decomposition of lignin, method for the preparation of alcohols and organic acids, method for the preparation of lignin-decomposition products, catalyst for the decomposition of aromatic hydrocarbons, method for releasing hydrogen ions, as well as porphyrin
Inventor: ISHIBASHI TORU
IPC: B01J31/02
Filed: 2009-08-11
Abstract: Disclosed is a porphyrin obtained by cultivating Escherichia coli that cannot express the gene ypjD (b2611) due to the variation thereof, wherein the porphyrin is free of any coordinated transition metal at the center of the porphyrin ring.
Patent NZ-613121-A (NZ)
Title: Cytotoxic benzodiazepine derivatives
Inventor: LI WEI
IPC: C07D519/00
Filed: 2012-02-15
Abstract: Disclosed are benzodiazepine derivatives with antiproliferative activity and more specifically to benzodiazepine compounds of formula (I)-(VII). The disclosure also provides conjugates of the benzodiazepine compounds linked to a cell-binding agent. The disclosure further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates.
Patent NZ-621811-A (NZ)
Title: Use of dig3 insecticidal crystal protein in combination with cry1ab
Inventor: STORER NICHOLAS P
IPC: C12N15/82
Filed: 2012-08-03
Abstract: Disclosed is a transgenic plant comprising a crylAb polynucleotide encoding a CrylAb insecticidal protein, and a DIG-3 polynucleotide encoding a DIG-3 insecticidal protein, wherein said DIG-3 polynucleotide hybridizes at 42° C in IX SSC with the complement of a polynucleotide that encodes a core toxin of SEQ ID NO: 2, wherein SEQ ID NO: 2 is disclosed in the specification.
Patent NZ-621977-A (NZ)
Title: A centrifugal separator
Inventor: ISAKSSON ROLAND
IPC: B04B11/00
Filed: 2012-08-31
Abstract: A centrifugal separator includes a frame (1) and a rotating part (2) having a spindle (6) and a centrifuge rotor (7) enclosing a separation space (8). An inlet channel (20) provides fluid communication into the separation space and includes a rotary channel part (21), a frame channel part (22), and a fluid seal (23) at the interface between the rotary and frame channel parts. An outlet channel (30) provides fluid communication out from the separation space and includes a rotary channel part (31), a frame channel part (32), and a seal (33) at the interface between the rotary and frame channel parts. The inlet and outlet channels are arranged concentrically with each other. A pump is provided to generate a leak flow across the appropriate seal interface in the direction from the outlet channel to the inlet channel to counteract leakage across the seal interface in the opposite direction. The pump may be incorporated into the structure of the seal or provided separately to pressurize the flow in the outlet channel so that fluid does not flow across the seal from the inlet channel into the outlet channel.
Patent NZ-622901-A (NZ)
Title: Anti-clog suction tip apparatus and methods
Inventor: HENSLER ROBERT SEAN
IPC: A61M1/00
Filed: 2012-08-25
Abstract: Various forms of anti-clog suction tips apparatus are disclosed. For example, an anti-clog suction tip apparatus includes a suction tip assembly having a suction tip with a suction opening at a first end thereof for removing debris through suction, a hose attachment portion for attaching the suction tip assembly to a suction source, and an ejection wire channel. The apparatus further includes an ejection wire assembly having an ejection wire extending within the channel and an ejection button integral with or connected to the ejection wire. Applying a force to the ejection button advances the ejection wire through the channel such that an end portion of the ejection wire enters the suction tip and dislodges debris clogging the suction tip. The ejection wire may include an enlarged end portion such as, for example a ball tip. One or more of the components of the apparatus may be single-use and disposable.
Patent NZ-623273-A (NZ)
Title: Sparc binding scfvs
Inventor: TRIEU VUONG
IPC: C07K19/00
Filed: 2009-12-07
Abstract: Disclosed is a composition comprising a single-chain variable fragment (ScFv) which binds to a Secreted Protein, Rich in Cysteines (SPARC protein), wherein the ScFv comprises SEQ ID NO: 116, as defined in the complete specification. Also disclosed is the use of the ScFv for the manufacture of a medicament for treating a mammal with a cancer.
Patent NZ-708090-A (NZ)
Title: Fused imidazole derivatives useful as ido inhibitors
Inventor: MAUTINO MARIO
IPC: C07D487/04
Filed: 2012-04-12
Abstract: Presently provided are IDO inhibitors and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated inimunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated with an infectious disease. In one embodiment the compound is 1-(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethyl)piperidin-I-yl)-2-(3-hydroxyphenyl)ethanone.
Patent NZ-720987-A (NZ)
Title: Seismic isolation apparatus
Inventor: KOCHIYAMA OSAMU
IPC: F16F15/04
Filed: 2013-06-11
Abstract: A seismic isolation apparatus having a laminated rubber body for isolating from seismic vibrations a structure; wherein at the time of horizontal deformation due to relative horizontal vibrations between the superstructure and substructure, overcomes stress concentrations present in the prior art that can cause buckling, said seismic isolation apparatus 1 includes an upper flange plate 2 which is connected to a superstructure; a lower flange plate 3 which is connected to a substructure; a laminated rubber body 7 which is provided between the upper flange plate 2 and the lower flange plate 3 and has rubber elastic material layers 4 and rigid material layers 5, both of which are alternately laminated in a vertical direction V; a columnar hole 8 provided in the laminated rubber body 7; and a vibrational energy absorbing body 9 disposed in the columnar hole 8. Said stress concentrations present in the prior art are therefore overcome by way of the plates increasing in diameter adjacent to the flange plates.
Patent NZ-725953-A (NZ)
Title: Monitoring an object
Inventor: VATN GUDBRAND
IPC: G08B21/00
Filed: 2012-10-24
Abstract: A system for tracing of an object, comprises a communication unit (100) which in a normalcy is placed close to the object. The communication unit (100) contains a reader (110). a radio station (120) adapted to communication with a base station (130) and an electrical energy supply (140). The system furthermore has an ID unit (125) in or at the object. The ID unit (125) has a unique ID. and contains a receiver and a transmitter adapted to transmit the unique ID of the chip as a response to an incoming signal from the reader (110). An alarm circuit (115) is placed between the reader (110) and the radio station (120). Alarm circuit is configured to trigger an alarm if the reader does not receive a response from the ID unit. The communication unit (100) may further comprise means for determining the geographical position (position finder) of the radio station (120). In an application for monitoring of animals the energy supply (140) may be charged by a generator which converts motion energy to chemical energy in the energy supply (140).
Patent NZ-739993-A (NZ)
Title: Method for the preparation of (4s)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide and recovery of (4s)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide by electrochemical methods
Inventor: PLATZEK JOHANNES
IPC: C07D471/04
Filed: 2016-08-18
Abstract: The present invention relates to a novel method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide of the formula (I) and for the recovery of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide of the formula (I) starting from (4R)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide of the formula ent-(I).
Patent NZ-740252-A (NZ)
Title: Antitumor agent including low-dose irinotecan hydrochloride hydrate
Inventor: OKABE HIROYUKI
IPC: A61K31/513
Filed: 2014-03-27
Abstract: Provided is a combination therapy which provides i) the combination of trifluridine (trifluorothymidine / TFT / FTD) and tipiracil hydrochloride (thymidine phosphorylase inhibitor / TPI); in combination with ii) irinotecan hydrochloride hydrate (CPT-11). The combination therapy is characterised in that the FTD/TPI combination drug is provided for administration at a reduced does amount of trifluridine (in the range of 35 to 70 mg/m2/day) combined with CPT-11 provided for administration at a dose in the range of 45 to 144 mg/m2/day.
Patent NZ-740820-A (NZ)
Title: Chimeric antigen receptors and uses thereof
Inventor: COOMBS JUSTIN
IPC: C07K19/00
Filed: 2016-09-10
Abstract: The present invention relates to chimeric antigen receptors (CARs) directed to cells expressing a dysfunctional or non-functional P2X purinoceptor 7 receptor. Further provided are methods of targeting neoplastic cells and tumours expressing a dysfunctional or non- functional P2X purinoceptor 7 receptor and methods of treating and preventing cancer is a subject.