Patent SG-11201906436V-A (SG)
Title: Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same
Inventor: LEE BONG-YONG
IPC: A61K31/4184
Filed: 2018-02-07
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 16 August 2018 (16.08.2018) WIP0 1 PCT ill mu °mons °nolo mo om Imo oimIE (10) International Publication Number WO 2018/147626 Al (51) International Patent Classification: CO7D 401/06 (2006.01) A61K 31/4184 (2006.01) A61K 31/454 (2006.01) (21) International Application Number: PCT/KR2018/001625 (22) International Filing Date: 07 February 2018 (07.02.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 10-2017-0016971 07 February 2017 (07.02.2017) KR (71) Applicant: DAEWOONG PHARMACEUTICAL CO., LTD. [KR/KR]; 35-14, Jeyakgongdan 4-gil, Hyang- nam-eup, Hwaseong-si, Gyeonggi-do 18623 (KR). (72) Inventors: LEE, Bong-Yong; 201-2103, 2183, Nam- busunhwan-ro, Seocho-gu, Seoul 06701 (KR). CHO, Min-Jae; 601-1304, 14-30, Jukjeon-ro 27beon-gil, Su- ji-gu, Yongin-si, Gyeonggi-do 16898 (KR). LEE, Hyung- Geun; A-103, 42-12, Pogok-ro 6lbeon-gil, Pogok-eup, Cheoin-gu, Yongin-si, Gyeonggi-do, 17027 (KR). JUNG, Myung-gi; #302, 325, Bundang-ro, Bundang-gu, Seong- nam-si, Gyeonggi-do 13584 (KR). OH, Yunju; #3002, 7, Pungdeokcheon-ro 160beon-gil, Suji-gu, Yongin-si, Gyeonggi-do, 16833 (KR). TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (74) Agent: YOU ME PATENT AND LAW FIRM; 115 Teheran-ro, Gangnam-gu, Seoul 06134 (KR). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, 1-1 EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, N 71- 1-1 (54) Title: NOVEL HETEROCYCLIC COMPOUND, ITS PREPARATION METHOD, AND PHARMACEUTICAL COM- POSITION COMPRISING THE SAME 1-1 O (57) : The present invention relates to a heterocyclic compound represented by Chemical Formula 1 that can be used for the \" prevention or treatment of diseases caused by abnormality in a PRS (prolyl-tRNA synthetase) activity, or a pharmaceutically acceptable 0 salt thereof, a method for preparing the same, and a pharmaceutical composition comprising the same.