baber/WOPTO huggingface dataset:
Patent CA-2840900-C (CA)
Inventor: LEE BONG HEE
IPC: A61P9/00
Filed: 2012-11-12
Granted: 2019-01-08
Abstract: La présente invention concerne une composition pharmaceutique destinée à prévenir ou traiter une cardiopathie ischémique et contenant, en tant que principe actif, un inhibiteur capable d'inhiber la synthèse ou la sécrétion d'AGE-albumine dans les cellules du système phagocytaire mononucléaire, l'AGE-albumine induisant l'apoptose des cellules myocardiques suite à l'apparition d'une cardiopathie ischémique. La présente invention concerne également un procédé de criblage à la recherche dudit inhibiteur. La composition pharmaceutique destinée à prévenir ou traiter la cardiopathie ischémique selon la présente invention peut être largement utilisée pour prévenir ou traiter diverses formes de cardiopathie ischémique et, notamment, l'infarctus du myocarde, car ladite composition pharmaceutique contient, en tant que principe actif, un inhibiteur de la synthèse ou de la sécrétion d'AGE-albumine par les cellules du système phagocytaire mononucléaire et ladite composition pharmaceutique peut, donc, inhiber ou réduire l'apoptose induite par l'AGE-albumine.
Patent CA-2847141-C (CA)
Title: Methods for establishing fluid communication between a sagd well pair
Inventor: ENGLEMAN RUSS
IPC: E21B43/24
Filed: 2014-03-21
Granted: 2018-04-17
Abstract: There is provided a method of establishing fluid communication in an interwell region between an injection well and a production well forming the well pair includes electrically heating the interwell region between injection well and production well.
Patent CA-2848195-C (CA)
Inventor: ANDERSSON RASMUS MATHIAS
IPC: G06F17/30
Filed: 2012-08-20
Granted: 2016-06-07
Abstract: Dans un mode de réalisation, le procédé consiste à identifier un ensemble de résultats de recherche en réponse à une requête de recherche; à afficher l'ensemble de résultats de recherche; à recevoir une interaction utilisateur en relation avec un premier résultat de recherche de l'ensemble de résultats de recherche; et en réponse à l'interaction utilisateur, si le premier résultat de recherche est associé à un ou plusieurs objets d'information, à étendre le premier résultat de recherche, consistant également à afficher le ou les premiers objets d'informations associés au premier résultat de recherche.
Patent CA-2850980-C (CA)
Inventor: AHLQVIST JEANNERET HELENA
IPC: B02C19/18
Filed: 2011-10-10
Granted: 2018-05-01
Abstract: The invention concerns a method of fragmenting and/or weakening of material (1) by means of high voltage discharges. The material (1) is together with a process liquid (5) introduced into a process area (2), in which two electrodes (3, 4) face each other at a distance, and is arranged therein in such a manner that the area between the two electrodes (3, 4) is filled with material (1) and process liquid (5). Between the two electrodes (3, 4) high voltage discharges are generated for fragmenting or weakening, respectively, of the material. According to the invention, during the fragmenting or weakening, respectively, of the material (1), process liquid (5) is discharged from the process area (2) and process liquid (5) is fed into the process area (2). The process liquid (5) which is fed has a lower electrical conductivity than the process liquid (5) which is discharged. It has shown that by this measure in the electrodynamic methods known today, the energy efficiency and the capability of comminuting hard and brittle material can considerable by improved.
Patent CA-2853393-C (CA)
Title: An integrated rolling curtain window
Inventor: LU XIANFENG
IPC: E06B9/42
Filed: 2014-06-03
Granted: 2016-10-04
Abstract: The present invention provides an integrated rolling curtain window in the filed of architectural components, to address the disadvantages of the existing rolling curtain window for poor universality. The integrated rolling curtain window of the invention includes a profile window. The integrated rolling curtain window further comprises a rolling curtain assembly having a window curtain cover assembly mounted on the top of the profile window, two windproof rails positioned on the front surface of both sides of the profile window, a first connection piece for removably mounting the window curtain cover assembly to the top of the profile window and a second connection piece for removably connecting the said two windproof rails to the front surface of both sides of the profile window respectively. The window curtain cover assembly has a curtain cloth component which could be rolled out and in, and both sides of the curtain cloth component move within the said two windproof rails respectively when the curtain cloth component is rolled out. The present invention has the advantages for good universality, simple installation and adaption to various profile windows.
Patent CA-2854297-C (CA)
Title: Conduit isole a chemise d'air et procede d'utilisation
Inventor: CARLAY II RONALD L
IPC: F16L59/14
Filed: 2014-06-12
Granted: 2016-11-08
Abstract: Conduit isolé comprenant une chemise gonflable entourant le conduit. La chemise est gonflée, préférablement avec de lair circulant dans le conduit, pour créer une condition statique dans lespace dair formé par la chemise afin doffrir une isolation supplémentaire au conduit. Lorsque la chemise est combinée à une isolation supplémentaire et à un matériau à faible émissivité, la valeur R du conduit peut être accrue de manière plus efficace des points de vue de la fabrication et du coût.
Patent CA-2854702-C (CA)
Inventor: ROSCH ALEXANDER
IPC: C01B3/34
Filed: 2013-02-21
Granted: 2016-02-02
Abstract: A safety means for protecting a plant section located on the pressure side of a jet compressor connected with a propellant system against the exceedance of an admissible pressure, comprising a controlled safety valve actuated by external energy, whose control means measures is connected with the plant section to be protected via at least one pressure tapping line, wherein the safety valve is arranged such that upon exceedance of the pressure in the protected plant section it can vent propellant from the propellant system.
Patent CA-2857789-C (CA)
Inventor: HARTLESS MAC L
IPC: H04B1/16
Filed: 2014-07-23
Granted: 2015-10-13
Abstract: Symbol sampling in a high time delay spread interference environment includes acquiring (602) a time varying baseband waveform. The waveform has a signal amplitude that varies between one of a plurality of symbol states. The waveform is sampled (603) at a rate of m times the symbol rate. During an evaluation time, an error value is calculated (604, 606) for each of m data sample positions. Each of the error values comprises an average distance between the measured value of the waveform as indicated by the data sample and a closest known symbol value. The error values are used to create an error surface. Thereafter, the error surface is modeled as a quadratic and an optimal sample time is determined (608, 610, 612) based on finding the time location where the quadratic surface is minimum. A sinc interpolator is then used to resample the data.
Patent CA-2860355-C (CA)
Inventor: LEPPERT KLAUS
IPC: B65B13/18
Filed: 2012-12-20
Granted: 2019-06-04
Abstract: The invention relates to a pneumatically actuated strapping apparatus for strapping plastic tape around a packaging item, comprising a motorized tensioning device and a motorized welding device for the plastic tape. The strapping apparatus is characterized in that the tensioning device and the welding device are driven by the same pneumatic motor (8). The direction of rotation of the pneumatic motor can be inverted, the pneumatic motor being connected to the devices by two freewheeling mechanisms releasing the devices in opposite directions. In order to keep power consumption for evacuating non-operational air low, in a particularly preferred embodiment, switching valves which automatically discharge the non-operational air to the exterior are integrated into the air intake ducts that are used as evacuation ducts for the non-operational air when the direction of rotation is inverted.
Patent CA-2862694-C (CA)
Title: Triazolo[4,5-d]pyrimidine derivatives
Inventor: DORSCH DIETER
IPC: A61P29/00
Filed: 2012-12-21
Granted: 2020-07-28
Abstract: The present invention relates to compounds of the formula (l): (see formula I) in which R1 and R2 have the meanings as indicated herein. These compounds are inhibitors of GCN2, and can be employed, inter alia, for the treatment of cancer.
Patent CA-2866998-C (CA)
Title: Crane assembly for a maintenance system for a wind turbine maintenance program
Inventor: CHIN HOWARD M
IPC: F03D13/25
Filed: 2014-03-12
Granted: 2015-09-22
Abstract: A crane assembly for use in an all-weather maintenance system for an offshore wind turbine maintenance program, the maintenance system including a capsule for transporting tools, parts and maintenance personnel to and from respective wind turbine towers, the crane assembly being provided for supporting a trolley for transporting capsules between the respective wind turbine towers and the maintenance vessel.
Patent CA-2871920-C (CA)
Inventor: SELNICK HAROLD G
IPC: A61K31/7056
Filed: 2013-05-03
Granted: 2021-03-09
Abstract: The present invention is directed to a compound of Formula (I) (see formula I) or a pharmaceutically acceptable salt thereof, and pharmaceutical formulations comprising the compound which are useful as O-linked N-acetylglucosaminidase (O-GlcNAcase) inhibitors, and thus may be useful for the treatment of certain disorders such as Alzheimer's disease including reducing NFTs and/or hyperphosphorylated tau. The invention is also directed to use of the compounds as O-GlcNAcase imaging agents.
Patent CA-2876312-C (CA)
Inventor: FISHER LEE
IPC: A61N1/36
Filed: 2013-06-17
Granted: 2019-01-15
Abstract: An implantable cuff includes an elastic collar, at least one conductive segment disposed on or within the elastic collar, and at least one conductor in electrical communication with the at least one conductive segment. The elastic collar defines an internal opening configured to receive an internal body tissue. At least a portion of the elastic collar includes a stiffening region having a stiffness greater than a second region of the elastic collar. The at least one conductor is configured to operably mate with an apparatus capable of delivering electrical stimulation to, and/or recording an electrical activity of, the internal body tissue.
Patent CA-2876893-C (CA)
Title: Hyperbright white roofing granules with high solar reflectance
Inventor: JOEDICKE INGO B
IPC: D06N7/04
Filed: 2013-06-19
Granted: 2021-12-28
Abstract: The invention provides a bright white refractory roofing granule, comprising a ceramic material formed from a substantially homogenous mixture of a ceramic-forming clay, sintering material, and optionally comprising silica particles, and other potential additives, said bright white refractory roofing granule having a total solar reflectance of at least 0.80 and a Hunter Color L-value of at least 85.0, together with processes for making and using the same.
Patent CA-2880054-C (CA)
Inventor: WILSON ANDREW D
IPC: G06F3/042
Filed: 2007-05-29
Granted: 2016-08-23
Abstract: Virtual controllers for visual displays are described. In one implementation, a camera captures an image of hands against a background. The image is segmented into hand areas and background areas. Various hand and finger gestures isolate parts of the background into independent areas, which are then assigned control parameters for manipulating the visual display. Multiple control parameters can be associated with attributes of multiple independent areas formed by two hands, for advanced control including simultaneous functions of clicking, selecting, executing, horizontal movement, vertical movement, scrolling, dragging, rotational movement, zooming, maximizing, minimizing, executing file functions, and executing menu choices.
Patent CA-2882443-C (CA)
Inventor: JANSEN BURKHARD
IPC: A61K31/713
Filed: 2003-08-21
Granted: 2016-12-13
Abstract: RNAi sequences that are useful as therapeutics in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease. These sequences target clusterin, IGFBP-5, IGFBP-2, both IGFBP-2 and -5 simultaneously, Mitf, and B-raf. The invention further provides for the use of these RNAi sequences in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease, and a method of treating such conditions through the administration of the RNA molecules with RNAi activity to an individual, including a human individual in need of such treatment.
Patent CA-2882825-C (CA)
Title: Housse de lavage a plat presentant deux surfaces de nettoyage
Inventor: SMEIJER DENNIS
IPC: A47L13/257
Filed: 2013-05-24
Granted: 2016-12-13
Abstract: L'invention concerne une housse de lavage à plat (1) destinée à être disposée sur un dispositif de fixation (1a) de la housse de lavage, comprenant un corps de base (2) longitudinal, le corps de base (2) présentant une première surface longitudinale (3) et une deuxième face longitudinale (4), disposées l'une en face de l'autre, au moins une couche en mousse (6) étant disposée entre les surfaces longitudinales (3, 4). Les deux surfaces longitudinales (3, 4) sont chacune réalisées en tant que surfaces de nettoyage et disposées de telle sorte qu'un élément support (5) en forme de plaque d'un dispositif de fixation (1a) de la housse de lavage peut être pris en sandwich entre elles. Pour réaliser et perfectionner une housse de lavage à plat afin qu'elle permette de nettoyer sans problème des surfaces situées dans une salle blanche, selon l'invention, le corps de base (2) peut absorber de manière réversible au moins le quadruple et au plus le vingtuple de son poids sec de liquide, la couche de mousse (6) ne présentant pas de fibres.
Patent CA-2883076-C (CA)
Inventor: GANAPATHIRAJU ARAVIND
IPC: G10L15/18
Filed: 2012-08-30
Granted: 2019-06-11
Abstract: A system and method are presented for predicting speech recognition performance using accuracy scores in speech recognition systems within the speech analytics field. A keyword set is selected. Figure of Merit (FOM) is computed for the keyword set. Relevant features that describe the word individually and in relation to other words in the language are computed. A mapping from these features to FOM is learned. This mapping can be generalized via a suitable machine learning algorithm and be used to predict FOM for a new keyword. In at least embodiment, the predicted FOM may be used to adjust internals of speech recognition engine to achieve a consistent behavior for all inputs for various settings of confidence values.
Patent CA-2883614-C (CA)
Inventor: DAY DAN DRESSKELL
IPC: B66F11/00
Filed: 2015-02-27
Granted: 2020-10-27
Abstract: Une méthode et un appareil pour fabriquer une structure daéronef sont décrits. Un support entraînable peut être entraîné dun premier emplacement à un deuxième emplacement pour le joindre à au moins un autre support entraînable pour former un système de support entraînable. Une structure peut être maintenue dans une position souhaitée au moyen de ce système de support entraînable.
Patent CA-2884778-C (CA)
Title: Procede et systeme de recuperation de sites fonctionnels sur un sorbant contamine par des sels thermostables
Inventor: KRUTKA HOLLY
IPC: B01D53/62
Filed: 2013-09-19
Granted: 2019-06-11
Abstract: La présente invention concerne un procédé de récupération de sites fonctionnels sur un sorbant de CO2 qui ont réagi avec un gaz acide (autre que C02) pour former des sels thermostables. Les sels thermostables sont un problème significatif pour la capture de CO2 à base de sorbant sec car avec le temps l'accumulation de sels thermostables réduira la fonctionnalité globale du sorbant de CO2. Un traitement chimique peut éliminer le gaz acide non-CO2 et récupérer les sites fonctionnels qui peuvent alors être utilisés pour plus d'adsorption de CO2.
Patent CA-2885297-C (CA)
Inventor: HEDBERG MAGNUS
IPC: F28F3/08
Filed: 2013-10-10
Granted: 2017-06-20
Abstract: A heat exchanger plate and a plate heat exchanger are provided.. The heat exchanger plate has a port hole with a reference point that coincides with a center point of a biggest imaginary circle that can be fitted into the port hole. The porthole has a form defined by a number of corner points of an imaginary plane geometric figure of which at least one is displaced from an arc of the circle, and the same number of thoroughly curved lines connecting the corner points. A first corner point is arranged closest to a transition between the first short side and the first long side and on a first distance from the reference point. Second and third corner points are arranged closest to the first corner point at second and third distances in clockwise and counterclockwise directions, respectively.
Patent CA-2885472-C (CA)
Inventor: MORISSET ROBERT J
IPC: B60R25/04
Filed: 2007-03-08
Granted: 2016-11-08
Abstract: A system and method for safely slowing or stopping a vehicle by selectively replacing a genuine engine control signal with a spoofed engine control signal to slow or stop a vehicle in a gradual or stepped manor. The operator is allowed control of the vehicle (e.g. genuine engine control signal) if the speed is below a threshold speed and the operator is denied control of the vehicle (e.g. spoofed engine control signal) if the speed is above the threshold speed, thus forcing the vehicle to slow to the threshold speed. The threshold is gradually reduced over time, causing the operator to stop the vehicle.
Patent CA-2895253-C (CA)
Inventor: TEAMEY KYLE
IPC: C25B3/25
Filed: 2013-12-23
Granted: 2022-03-01
Abstract: La présente invention concerne un procédé et un système de production d'acide oxalique, ainsi que des produits de la réduction de l'acide oxalique. La production d'acide oxalique et les produits de la réduction de l'acide oxalique peuvent comprendre la conversion électrochimique de CO2 en oxalate et en acide oxalique. Le procédé et le système de production d'acide oxalique, et les produits de la réduction de l'acide oxalique peuvent également comprendre l'acidification de l'oxalate en acide oxalique, la purification de l'acide oxalique et l'hydrogénation de l'acide oxalique afin d'obtenir des produits de la réduction de l'acide oxalique.
Patent CA-2895693-C (CA)
Inventor: HOSOKAWA KAZUYA
IPC: G01N33/86
Filed: 2013-12-20
Granted: 2017-02-28
Abstract: A method for comprehensively and quantitatively analyzing platelet aggregability, and stability and persistence of platelet aggregates, which method comprises the steps of: reacting a platelet-activating reagent with blood in a closed container; injecting a liquid which is not mixable with blood into the container using a pump connected to a first end of the container, thereby pushing the mixture of the platelet-activating reagent and the blood out from the container and allowing the mixture to pass through a filter in a filter device connected to a second end of the container; and measuring the pressure exerted on the pump.
Patent CA-2899539-C (CA)
Inventor: VOGT SEBASTIAN
IPC: B67B7/20
Filed: 2015-08-05
Granted: 2017-07-18
Abstract: The invention relates to an opening device for the opening of a monomer liquid container (1) comprising a positioning aid (6) for positioning of the monomer liquid container (1), an opening facility (8) for the opening of the monomer liquid container (1), whereby the opening facility (8) is supported such as to be mobile with respect to the positioning aid (6) and/or the positioning aid (6) is supported such as to be mobile with respect to the opening facility (8), and at least one elastically deformable energy-storing element (9) for storage of elastic energy, whereby a motion of the opening facility (8) and/or a motion of the positioning aid (6) can be driven by the elastic energy of the at least one elastically deformable energy-storing element (9), and the monomer liquid container (1) can be opened by the motion of the positioning aid (6) with the monomer liquid container (1) and the opening facility (8) with respect to each other. The invention also relates to a vacuum mixing system having an opening device of this type and to a method for the opening of a monomer liquid container (1).
Patent CA-2901451-C (CA)
Title: Human igm antibodies with the capability of inducing remyelination, and diagnostic and therapeutic uses thereof particularly in the central nervous system
Inventor: RODRIGUEZ MOSES
IPC: C12P21/08
Filed: 2000-05-30
Granted: 2020-04-07
Abstract: Methods are described for treating demyelinating diseases in mammals, such as multiple sclerosis in humans, and viral diseases of the central nervous system of humans and domestic animals, such as post-infections encephalomyelitis, or prophylactically inhibiting the initiation or progression of demyelination in these disease states, using human monoclonal autoantibodies characterized by their ability to bind structures and cells within the central nervous system. In particular, the methods utilize human monoclonal antibodies selected from the group of sHIgM22 (LIM 22), sHIgM46 ebvHlgM MSI19D10, CB2bG8, AKJR4, CB2iE12,C B2iE7 and MSI 19E5, monomers thereof, active fragments thereof and isolated or synthetic human or humanized autoantibodies having the characteristics of the foregoing. Nucleic acids and DNA molecules encoding the human monoclonal antibodies, or portions thereof, are provided. The invention also extends to the preparation and use of human polyclonal and monoclonal autoantibodies, monomers thereof, active fragments, peptide derivatives and fragments, and analogs, cognates, agonists and the like corresponding materials, and their use in diagnostic and therapeutic applications. For example, the autoantibodies, monomers, fragments, haptens, and peptide equivalents, are useful in the promotion of neural regeneration and neuroprotection, and therapeutic compositions and vaccines containing peptides or antibodies are included and presented.
Patent CA-2903588-C (CA)
Inventor: BENDELS STEFANIE
IPC: C07D519/00
Filed: 2014-04-28
Granted: 2021-10-26
Abstract: Abstract The invention relates to a compound of formula (I) R                                      ,R3 N N-----N I R1N%-------N \ A¨R4 (I) including pharmaceutically acceptable salts or esters thereof. The compound of formula (I) can be used as a medicament, for example, in the treatment or prophylaxis of pain, atherosclerosis, age-related macular degeneration, diabetic retinopathy, glaucoma, retinal vein occlusion, retinopathy of prematurity, ocular ischemic syndrome, geographic atrophy, diabetes mellitus, inflammation, inflammatory bowel disease, ischemia-reperfusion injury, acute liver failure, liver fibrosis, lung fibrosis, kidney fibrosis, systemic fibrosis, acute allograft rejection, chronic allograft nephropathy, diabetic nephropathy, glomerulonephropathy, cardiomyopathy, heart failure, myocardial ischemia, myocardial infarction, systemic sclerosis, thermal injury, burning, hypertrophic scars, keloids, gingivitis pyrexia, liver cirrhosis or tumors, regulation of bone mass, amyotrophic lateral sclerosis, multiple sclerosis, Alzheimer's disease, Parkinson's disease, stroke, transient ischemic attack or uveitis. Date recue/Date Received 2020-08-28
Patent CA-2912415-C (CA)
Inventor: TAKAGI SHUSAKU
IPC: F17C1/06
Filed: 2014-04-24
Granted: 2017-08-29
Abstract: The purpose of the present invention is to provide an inexpensive accumulator that can ensure safety. The accumulator (10) accommodates pressurized hydrogen and has a liner layer (12) that accommodates hydrogen and a carbon fiber reinforced resin layer (14) that is disposed more to the exterior than the liner layer (12). In addition, the liner layer (12) is made of a low alloy steel, and the carbon fiber of the carbon fiber reinforced resin layer (14) is made of a pitch-based carbon fiber.