baber/WOPTO huggingface dataset:
Patent DE-60131401-T2 (DE)
Inventor: PETTIS RONALD J
IPC: A61K38/22
Filed: 2001-06-29
Granted: 2008-05-15
Abstract: The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gange needles, especially microneedles, placed in the intradermal space to deliver the substance to the intrademial space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient. Delivery devices which place the needle outlet at an appropriate depth in the intradermal space and control the volume and rate of fluid delivery provide accurate delivery of the substance to the desired location without leakage.
Patent DE-60132700-T2 (DE)
Inventor: BALTHASART DOMINIQUE
IPC: C07D303/08
Filed: 2001-06-26
Granted: 2009-02-12
Abstract: Process for manufacturing oxirane by reaction of an olefin with a peroxide compound in the presence of a catalyst and a solvent in at least two reactors arranged in series, each of which contains a portion of catalyst, according to which the peroxide compound is introduced only into the first reactor, the subsequent reactor(s) not being fed with fresh peroxide compound, but only with the peroxide compound which is present in the medium obtained from the preceding reactor and which was not consumed in this preceding reactor.
Patent DE-60206362-T2 (DE)
Inventor: LOVISA STEPHANE
IPC: H04J3/06
Filed: 2002-05-06
Granted: 2006-06-22
Abstract: The method for protected transmission between two nodes (1,2) of an optical communication network, where the nodes are linked by a bidirectional main line and a bidirectional relief line, comprises the steps of transmitting the protected data on the main line, transmitting the supplementary data on the relief line, and following the detection of a loss of the main-line signal in reception at instants (51,53) by the nodes (1,2), respectively, the interruption of the data emission at instants (52,54) on the main line by the respective node, and the emission start of the protected data on the relief line at instants (55,56) by that node. That is both nodes (1,2) can switch the emission of the protected data to the relief line.  The detection of a loss of the signal is implemented by detecting a loss of the clock signal. The interruption of the emission on the main line comprises the extinction of laser at the node which emits on the main line. The step of interrupting the data emission on the main line and the emission start on the relief line is followed by the steps of sending a test signal at instants (57,58) on the main line by the respective node, and sending a reception acknowledgment signal at instant (60) on the main line when the node receives the test signal. When the reception acknowledgement signal is received, the node interrupts the emission of the protected data on the relief line and emits the protected data on the main line. The method also comprises the step of sending a confirmation signal on the main line by a node on receiving the reception acknowledgment signal. The test signal, the reception acknowledgment signal, and the confirmation signal are in the form of pulses distinguished by the length.
Patent DE-60207670-T2 (DE)
Inventor: BALDINUCCI MAURIZIO
IPC: F04B7/00
Filed: 2002-10-23
Granted: 2006-09-07
Abstract: The invention concerns a concrete pump, of the type comprising a pair of pumping cylinders (3) acting, alternately, to draw the concrete from a hopper (2) and introduce it, by means of an oscillating valve (S-valve 7), into a duct conveying and delivering the material, the movement of said S-valve (7) being controlled by an actuator (8) operated by a control unit. Said pump also comprises a sensor (15) of the working pressure which causes, by means of said control unit, the working of means (16, 9) to adjust the working pressure of said actuator (8) according to the type of concrete being pumped. <IMAGE>
Patent DE-60210456-T2 (DE)
Inventor: COSTANTINO PAOLO
IPC: A61K39/00
Filed: 2002-06-20
Granted: 2006-11-16
Abstract: The invention provides an immunogenic composition comprising a meningococcal serogroup A conjugate and a meningococcal serogroup C conjugate, and further comprising (i) an aluminium phosphate or an aluminium hydroxide adjuvant and (ii) a buffer.
Patent DE-60214049-T2 (DE)
Inventor: RUBIE ERIC W
IPC: A61F2/50
Filed: 2002-02-07
Granted: 2007-03-01
Abstract: A lower leg prosthesis comprises a lower foot plate (10) and an upper foot plate (12) disposed in spaced relationship to each other. <??>The plates are elongated and aligned along a longitudinal axis, wherein the plates both are configured to be flexible in directions along the longitudinal axis, and wherein the lower foot plate (10) includes an outer portion that extends beyond the periphery of the upper foot plate. An intermediate elastomeric layer (14) is disposed between and attaches the lower foot plate and the upper foot plate. The elastomeric layer extends over a substantial portion of the upper surface of the outer portion of the lower foot plate (10), including to a substantial portion of the periphery of the lower plate. <IMAGE>
Patent DE-60219351-T2 (DE)
Inventor: TAMMI MIKKO
IPC: G10L19/12
Filed: 2002-12-13
Granted: 2007-08-02
Abstract: For determining a long-term-prediction delay parameter characterizing a long term prediction in a technique using signal modification for digitally encoding a sound signal, the sound signal is divided into a series of successive frames, a feature of the sound signal is located in a previous frame, a corresponding feature of the sound signal is located in a current frame, and the long-term-prediction delay parameter is determined for the current frame while mapping, with the long term prediction, the signal feature of the previous frame with the corresponding signal feature of the current frame. In a signal modification method for implementation into a technique for digitally encoding a sound signal, the sound signal is divided into a series of successive frames, each frame of the sound signal is partitioned into a plurality of signal segments, and at least a part of the signal segments of the frame are warped while constraining the warped signal segments inside the frame. For searching pitch pulses in a sound signal, a residual signal is produced by filtering the sound signal through a linear prediction analysis filter, a weighted sound signal is produced by processing the sound signal through a weighting filter, the weighted sound signal being indicative of signal periodicity, a synthesized weighted sound signal is produced by filtering a synthesized speech signal produced during a last subframe of a previous frame of the sound signal through the weighting filter, a last pitch pulse of the sound signal of the previous frame is located from the residual signal, a pitch pulse prototype of given length is extracted around the position of the last pitch pulse of the sound signal of the previous frame using the synthesized weighted sound signal, and the pitch pulses are located in a current frame using the pitch pulse prototype.
Patent DE-60221827-T2 (DE)
Inventor: HELMERSSON STURE
IPC: G21C3/18
Filed: 2002-06-07
Granted: 2008-05-08
Abstract: The present invention relates to a fuel rod for a nuclear plant and a plenum spring arranged to be provided in a fuel rod. The fuel rod ( 1 ) comprises a cladding tube ( 2 ) sealed at its ends by end plugs ( 3, 4 ), a plurality of fuel pellets ( 5 ) stacked on each other inside the cladding tube ( 2 ) such that they form a column of pellets and said plenum spring ( 6 ) arranged to hold with a spring force the column of pellets against the lower second end of the cladding tube ( 2 ) during operation. The plenum spring ( 6 ) comprises a first length variable part ( 8 ) which abuts the uppermost located fuel pellet ( 5 ) in the column of pellets with an end portion ( 9 ), a second part ( 10 ) which allows engagement of the plenum spring ( 6 ) against an inner surface of the cladding tube ( 2 ) by a radially outwardly directed pressure and a third part ( 11 ) which allows releasing of the second part ( 10 ) of the plenum spring ( 6 ) in the cladding tube ( 2 ) during operation of the nuclear plant.
Patent DE-60224550-T2 (DE)
Inventor: AKERBLAD PETER
IPC: G01N5/00
Filed: 2002-10-03
Granted: 2009-01-22
Abstract: The invention relates to a method for identification of a compound which modulates pre-adipocyte differentiation comprising testing whether the compound modulates the activity and/or amount of O/E-1 and/or O/E-2 and/or O/E-3. The invention also relates to use of a compound able to modulate the activity or amount of O/E-1 and/or O/E-2 and/or O/E-3 in preparation of a medicament for the treatment or prevention of atherosclerosis, dyslipidemia, IRS, and type 2 diabetes.
Patent DE-60300594-T2 (DE)
Inventor: SERPELLONI MICHEL
IPC: A23L27/30
Filed: 2003-03-21
Granted: 2006-01-19
Abstract: Liquid maltitol composition (I) with a solids content of 70-85 wt.% comprises (% dry weight basis): (a) maltitol (94-98); (b) sorbitol (0.2-3); (c) maltotriitol  (0.1-3); and (d) at least one trisaccharide (DP3) polyol selected from panitol, isomaltotriitol and isopanitol in an amount such that the maltotriitol content is less than 10% of the total DP3 polyol content.  Independent claims are also included for:  (1) production of (I) by preparing a syrup with a maltitol content of 94-98 wt.% (dry basis), adding sorbitol and DP3 polyols in the indicated amounts above and adjusting the solids content;  (2) production of confectionery products in which the addition of a filler in the form of maltitol powder is at least partially replaced by the addition of (I) or the addition of a filler by dissolving maltitol powder in water is at least partially replaced by the addition of (I);  (3) confectionery products produced as above;  (4) production of a chewing gum comprising preparing gum base (5-95 %), malitol powder (1-95 %) with maltitol syrup (0.5-50 %) and sorbitol syrup (0-50%), glycerol (0-30 %), flavor (0.1-10 %) and intense sweetener (0.001-1 %), and mixing them together with the sorbitol and glycerol last; and (5) production of a hard sugar coating on a product by application of a coating syrup comprising maltitol and binder in which all or part of the coating syrup or binder is replaced by (I).
Patent DE-60301124-T2 (DE)
Inventor: NOORDHUIS JOEKE
IPC: A47J31/06
Filed: 2003-09-01
Granted: 2006-03-30
Abstract: A pad support for a beverage maker includes a bottom that forms a barrier for beverage liquid flowing from a supported pad, a discharge opening in the bottom for discharging beverage liquid through the bottom, and a nozzle restricting the discharge opening for generating a beverage liquid jet from the nozzle. Pad support projections are provided that have innermost support projections projecting from the bottom at positions circumferentially distributed around the discharge opening. Seen in top plan view towards the bottom, at least some of the innermost support projections have a cross-section that is elongate in a radial direction with respect to the discharge opening.
Patent DE-60301768-T2 (DE)
Inventor: BUISSON ALAIN
IPC: F21V9/00
Filed: 2003-07-02
Granted: 2006-05-18
Abstract: The indicator light includes a lamp (2), a reflector (3), and a cover glass (6). An additional intermediate screen carries a series of prisms (7c) on one surface, and a series of colored seatings on the opposite surface. Light leaving the lamp passes through clear areas between the color zones, whilst externally the lamp cover appears colored. The indicator light for a motor vehicle comprises a lamp (2) and a reflector (3), with a cover glass (6). Between the cover glass and the reflector there is an optical screen (5), and then between this and the glass there is an additional intermediate screen. On its face directed towards the optical screen there is a series of prisms (7c), and on the surface facing the glass there is a series of seatings (10) filled with a colored material (9). These seatings are lined up with the prisms. Between the prisms there are plane uncolored zones (8). The action of the prisms is such as to ensure that the light emerging from the lamp is channeled through the uncolored zones (8).
Patent DE-60313154-T2 (DE)
Inventor: KIMURA MASAHIRO
IPC: G06K15/10
Filed: 2003-08-26
Granted: 2007-12-20
Abstract: A data transferring apparatus has an ASIC (Application Specific Integrated Circuit), and the ASIC incorporates an interface unit, a head controlling unit, a receiving buffer unit and a DECU, which are coupled to be capable of transferring data. The DECU incorporates a development processing controller having a decode circuit for performing hardware development on compressed recording data, and a line buffer storing developed recording data. The DECU and the head controlling unit are coupled by an internal bus IB in order to perform data transfer. <IMAGE>
Patent DE-60317854-T2 (DE)
Inventor: HATHAWAY THOMAS
IPC: F01L1/20
Filed: 2003-06-30
Granted: 2008-11-27
Abstract: The invention relates to a tool comprising :  a valve lash fastener-driver; a valve lash adjusting member-driver ; a valve lash measurer; and a controller connected to and operably controlling movement of the fastener-driver, member-driver and valve lash measurer; the controller operably adjusting valve lash by selectively energizing and deenergizing the fastener-driver and member-driver; and the controller operably verifying the actually adjusted valve lash in an automatic manner based at least in part on the valve lash measurer output signal.  <??>The invention also relates to a valve lash setting tool and to a method using a tool to set valve lash. <IMAGE> <IMAGE>
Patent DE-60320573-T2 (DE)
Inventor: PORRO DANILO
IPC: C12N1/16
Filed: 2003-11-06
Granted: 2009-05-28
Abstract: Producing a protein comprises expressing and secreting a protein expressed by Zygosaccharomyces bailii strain.  Producing a protein comprises: (a) culturing a Zygosaccharomyces bailii strain; (b) expressing and secreting the protein; and (c) isolating the protein. An Independent claim is also included for a Z. bailii strain expressing and secreting a heterologous protein.
Patent DE-68902999-T2 (DE)
Inventor: WILLIAMSON NIGEL D L
IPC: F16L15/04
Filed: 1989-01-20
Granted: 1993-03-04
Abstract: A fluid coupling assembly particularly adapted for connecting hydraulic conduits to the ports of a fluid manifold. The coupling comprises a male member (44) which is threadedly connected to the port and which includes tapered locking surfaces (64,62) on the male and female members, respectively, that are in tight frictional engagement when the male member is threaded into the female member (34). An O-ring (60) is positioned in a pocket (58) and disposed between the threads and the tapered locking surfaces to isolate the locking surfaces from hydraulic fluid, thereby ensuring a dry, frictional wedge lock. The O-ring is of a size that permits it to move axially in the pocket. In a modified embodiment of the coupling, there is provided an adjustable fitting which includes a lock nut (76) having a skirt portion (84) that is wedged into the tapered O-ring pocket (86).
Patent DE-68911585-T2 (DE)
Inventor: HOARTY JOHN TERRENCE
IPC: C04B24/08
Filed: 1989-05-10
Granted: 1994-05-11
Abstract: Cement compositions containing fly ash having a carbon content are given satisfactory air entrainment by including a water soluble C8 fatty acid salt.
Patent DE-68917135-T2 (DE)
Inventor: KALLESOEE HERLUF
IPC: B27M3/00
Filed: 1989-02-23
Granted: 1995-03-23
Abstract: PCT No. PCT/DK89/00042 Sec. 371 Date Oct. 25, 1990 Sec. 102(e) Date Oct. 25, 1990 PCT Filed Feb. 23, 1989 PCT Pub. No. WO89/08016 PCT Pub. Date Sep. 8, 1989.A method and apparatus for automatically feeding stave members wherein each newly introduced stave is laterally automatically displaced inwardly against a free edge of a previously laid out layer of stave members such that a close connection is achieved by successive displacements of only a single stave member at a time. A feeder feeds the stave members from a stationary feeding area and a feeding carriage picks up the stave members and delivers the stave members to a carrier surface.
Patent DE-68923360-T2 (DE)
Inventor: SILVER JULES DR
IPC: A23D7/015
Filed: 1989-04-06
Granted: 1996-03-14
Abstract: A method fo the preparation of a low-fat butter of margarine product for use as a table spread or for other uses, including cooking, baking, etc. . The product is prepared by plasticizing a composition containing from about 15% to about 50% lipid, preferably butter fat; an amount of protein, preferably dairy protein, sufficient to emulsify the lipid but insufficient to stabilize the lipid against plasticization; and from about 40% to about 60% moisture. Salt, butter coloring and butter flavoring are preferably also included. The plasticization is achieved by subjecting the composition to the high speed cutting action of a sharp bladed food comminuter for a period of time sufficient to plasticize the composition. The product is a smooth plastic spreadable butter substitute containing nutritious protein, which is low in fat and does not require the need for emulsifiers and stabilizers. The product is spreadable immediately after removal from refrigeration, as well as at normal room temperatures.
Patent DE-69000500-T2 (DE)
Inventor: LERMAT YVES
IPC: C09J175/04
Filed: 1990-01-08
Granted: 1993-04-15
Abstract: Crosslinkable hot-melt adhesive composition based on ethylene-vinyl acetate copolymer containing hydroxyl and polyisocyanate functional groups, characterised in that it is in the form of a prepolymer containing free isocyanate functional groups resulting from the reaction of the ethylene-vinyl acetate copolymer containing hydroxyl functional groups and of polyisocyanate in excess. 
<??>This composition is obtained by reaction in the molten state of a mixture of an ethylene-vinyl acetate copolymer containing hydroxyl functional groups with a polyisocyanate in excess, an adhesive (tackifying) resin being optionally added to the reaction mixture.
Patent DE-69001532-T2 (DE)
Inventor: MULLEMAN MICHEL
IPC: F02K9/92
Filed: 1990-10-03
Granted: 1993-12-02
Abstract: The bomb body is equipped at its rear end with a propulsion unit 3, at the outlet of which is arranged a jet collector 5 having a plurality of conduits 6 and encased in a cover 7. The cover 7 is kept in position by cables 8. Articulated on the cover 7 are traps 13 which, under the effect of the pressure of the jet issuing from the conduits 6, are unfolded forwards over a limited stroke, thereby deflecting said jet forwards in order to ensure the drag of the bomb. After a reduction in speed of the bomb, measured by a device 11, a pyrotechnic system 10 is controlled so as to ensure the severance of the cables 8 and therefore the ejection of the cover 7 and the restoration of the propulsion of the bomb. The device automatically ensures the braking back of a bomb after its release and the restoration of the propulsion of the latter when the speed of the bomb is below a predetermined value. <IMAGE>
Patent DE-69022393-T2 (DE)
Inventor: PUGIA MICHAEL J
IPC: G01N33/72
Filed: 1990-12-12
Granted: 1996-03-28
Abstract: A new and improved test device and method of determining the presence or concentration of a peroxidatively active substance, such as hemoglobin, in a test sample are disclosed. The test device includes a test pad comprising a suitable carrier matrix incorporating an indicator reagent composition capable of interacting with a peroxidatively active substance to produce a detectable or measurable response. In addition, a new and improved indicator reagent composition, comprising an indicator dye, such as a redox indicator, like a benzidine indicator; a hydroperoxide; a metal ion complex; and a phosphorus compound having the general structural formula <CHEM> wherein R1 or R2 is selected from the group consisting of hydrogen, an unsubstituted or a substituted alkyl moiety including from one to about twelve carbon atoms, an unsubstituted or a substituted aromatic moiety and a residue of an aliphatic or an aromatic polyhydric compound; and wherein X is 0, S or NH; such as glyceryl-2-phosphate or phenyl dihydrogen phosphate, is incorporated into a carrier matrix, or used in a wet phase assay, to provide a more accurate and trustworthy assay of a test sample for a peroxidatively active substance. The improved method and composition are especially useful in the assay of urine for occult blood.
Patent DE-69025612-T2 (DE)
Inventor: ROBINSON STEPHEN E
IPC: G01R33/10
Filed: 1990-12-13
Granted: 1996-06-13
Abstract: Signals produced by brain activity are measured by each sensor of an array of magnetic and/or electrical sensors external to but proximate to the head (or other portion of the body) of a subject. The measurements obtained simultaneously from all of the sensors are combined in a manner to permit selective measurement of the electrical activity from a specified location within the body, or alternatively, to permit the location in the body producing a particular type of response to be identified. The instantaneous measurement of each sensor is scaled by a weighting coefficient for that sensor, and the products added over all of the sensors. Preferably, the weighting coefficients are calculated from the covariance matrix of the measurements made by the array of sensors. Alternatively, the weighting coefficients may be calculated from a mathematical model of the portion of the body being measured that includes information on the shape of the potential source, the extent or type of source activity, the electrical and magnetic properties of the media, and the locations and orientations of the sources and the sensors.
Patent DE-69027527-T2 (DE)
Inventor: AXELGAARD JENS
IPC: A61N1/04
Filed: 1990-04-11
Granted: 1997-02-13
Abstract: A flexible transcutaneous electrical nerve and/or muscle stimulation electrode is provided which utilizes a conductive material (72), preferably a conductive fabric, and electrical shunt means (74) disposed along the conductive material (72) for causing more uniform resistivity between any two equally spaced apart points on the conductive material (72) than without the electrical shunt means (74). Further adjustment of the electrical conductivity may also be achieved by varying the conductivity of individual fibers utilized in the conductive fabric.
Patent DE-69029365-T2 (DE)
Inventor: WEIBEL MICHAEL K
IPC: A23L29/231
Filed: 1990-10-30
Granted: 1997-04-10
Abstract: Sugar beet pectins are provided, which are characterized by unique properties which render them particularly useful in the preparation of food or drug comestibles. By incorporating the sugar beet pectins into food or drug products, improved properties, including physicochemical, rheological and nutritional properties are obtained.
Patent DE-69033376-T2 (DE)
Inventor: SAND BRUCE J
IPC: A61B18/20
Filed: 1990-06-29
Granted: 2000-05-11
Abstract: Apparatus for shrinking collagen tissue includes means for generating radiation in a wavelength range of 1.80 to 2.55 microns. The radiation is delivered to the tissue in a controlled pattern in order to achieve selective shrinkage thereof. The radiation generator is conveniently a laser capable of generating coherent energy in the manner required.