baber/WOPTO huggingface dataset:
Patent EP-1620455-A4 (EP)
Title: Process for preparing guggulsterones and guggulsterol
Inventor: KANG HEONJOONG
IPC: C07J13/00
Filed: 2004-04-24
Abstract: The present invention relates to a method for selective preparing 4,17 (20)- E -pregnadiene-3,16-dione ( E -guggulsterone) of the formula (III) and 4,17 (20)- Z -pregnadiene-3,16-dione (Z-guggulsterone) of the formula (IV) having an effect of lowering the elevated low density lipoprotein (LDL) and high levels of the cholesterol effectively, and elevating the low levels of the high density lipoprotein (HDL) from a easy-available steroid of the following formula (I).  Also, the present invention provides a method for preparation of the compound of the above formula (II).
Patent EP-1661580-A4 (EP)
Inventor: TOGUCHIDA JUNYA
IPC: A61K38/27
Filed: 2004-07-23
Abstract: L'invention concerne un remède destiné à traiter des maladies liées au cartilage contenant, en tant que principe actif, une substance possédant une activité agoniste à EP2 et/ou EP3. Une substance présentant une activité agoniste à EP2 et/ou EP3 comporte des effets facilitant la chondrogénèse, la croissance chondrocyte, la différenciation chondrocyte, l'inhibition de la calcification du cartilage et de sa dégradation ou des effets facilitant l'expression ARNm intégrine, fibronectine, et cycline D1 et l'inhibition de l'expression ARNm d'ostéopontine, et, se révèle donc utile en tant que remède destiné à traiter les maladies liées au cartilage.
Patent EP-1683857-A4 (EP)
Title: Method of preparing cell concentrate and cell composition
Inventor: TERASHIMA SHUJI
IPC: C12N5/0789
Filed: 2004-10-08
Abstract: It is an object of the present invention to provide: a method for preparing a cell concentrate which efficiently separates nucleated cells from unnecessary cells contained in a cell-containing solution by simple operations, thereby reducing the volume of a solution used for cryopreservation that contains the nucleated cells, when the cell-containing solution that contains the nucleated cells and the unnecessary cells has been filtrated with a filter device and when a recovery solution is then introduced into the filter device to recover the nucleated cells captured by a filter material; and a cell composition. The present invention provides a method for preparing a cell concentrate, which comprises: introducing a cell-containing solution that contains nucleated cells and unnecessary cells into a filter device comprising a filter material for substantially capturing the nucleated cells and for substantially giving passage to the unnecessary cells, so as to capture the nucleated cells by the above-described filter material and to discharge the unnecessary cells from the above device; and introducing a recovery solution into the above-described filter device, so as to recover the nucleated cells captured by the above-described filter material, wherein the above-described method is  characterized in that  the cell-containing solution that contains nucleated cells and unnecessary cells are separated into a layer that is rich in nucleated cells and a layer that is rich in unnecessary cells, the layer rich in unnecessary cells is first introduced into the above-described filter device, and the layer rich in nucleated cells is then introduced therein, so as to discharge the unnecessary cells remaining in the above-described filter device while capturing the nucleated cells by the above-described filter material, and a recovery solution is then introduced into the above-described filter device, so as to recover the nucleated cells captured by the above-described filter material.
Patent EP-1673630-A4 (EP)
Inventor: EBERT MATTHIAS
IPC: C12Q1/68
Filed: 2004-10-18
Abstract: L'invention concerne des méthodes permettant d'établir le pronostic d'une maladie néoplasique/prénéoplasique chez un vertébré, la maladie étant associée à un tissu exprimant MN normalement, mais dont l'expression MN s'arrête ou diminue pendant la carcinogenèse. Les maladies néoplasiques/prénéoplasiques pouvant faire l'objet de ces méthodes pronostiques touchent la muqueuse gastrique, la vésicule biliaire, les conduits biliaires et les cellules canalaires des glandes duodénales. Une méthode pronostique exemplaire consiste à comparer le niveau de produit d'expression du gène MN dans un échantillon tissulaire prélevé sur un patient avec le niveau de produit d'expression du gène MN moyen, défini dans des échantillons tissulaires néoplasiques/prénéoplasiques analogues. Un niveau de produit d'expression du gène MN se situant au-dessus de la moyenne constitue un moins bon pronostic pour le patient. Les produits d'expression du gène MN utilisés dans la mise en oeuvre des méthodes selon l'invention comprennent la protéine MN, le polypeptide MN et/ou des acides nucléiques MN.
Patent EP-1729250-A4 (EP)
Inventor: YAMADA KAZUKI
IPC: G06Q10/00
Filed: 2005-02-25
Abstract: コンピュータに電子マネーカードを処理する端末としての機能を発揮させるプログラムを用意し、これを加盟店に配布する。加盟店は、これをコンピュータにインストールし、加盟店端末として使用する。インストール先のコンピュータは、例えばパーソナルコンピュータなどの汎用のコンピュータでよく、加盟店側の端末設置負担や電子マネーセンタ側の端末管理負担もを大幅に軽減することができる。端末アプリは、インストール時にインストール先のコンピュータに備えられている所定のハードウェアのハードウェア情報を収集して記憶するように構成されている。そして、端末アプリは、加盟店端末の立ち上げの際に、当該ハードウェアからハードウェア情報を取得して、インストール時に記憶したハードウェア情報と比較する。
Patent EP-1719906-A4 (EP)
Inventor: AKABANE AKIRA
IPC: F02M61/16
Filed: 2005-02-25
Abstract: 後端面を可動側吸引作用面とした可動コアの一部を囲繞する非磁性円筒体の前端が、弁ハウジングの一部を構成する磁性円筒体の後端に同軸に結合され、非磁性円筒体の後部には、前端面を固定側吸引作用面とした固定コアの前部が、可動側吸引作用面に固定側吸引作用面を対向させるようにして嵌合、固定される電磁式燃料噴射弁において、固定コア（２２）の前部が、固定側吸引作用面（４２）に対応する部分では非磁性円筒体（２６）の中間部内面に密接するようにして、非磁性円筒体（２６）に嵌合、固定され、固定側吸引作用面（４２）に面一に連なる平面部（４４ａ）を有する環状凹部（４４）が、可動コア（１８）の後部外周との間に環状室（４５）を形成するようにして非磁性円筒体（２６）の内面に設けられるようにした。これにより、固定コアおよび可動コアの対向面の面積を極力大きく設定可能とし、切粉や磁性粉の堆積、付着を防止することができる。
Patent EP-1907089-A4 (EP)
Title: Separation of proteins based on isoelectric point using solid-phase buffers
Inventor: BOSCHETTI EGISTO
IPC: B01L3/00
Filed: 2006-01-19
Abstract: Proteins can be separated from mixtures, based on their pI values, through the use of a series of chromatographic materials, each comprising a solid buffer and an ion exchange resin. Each solid buffer generates a stable pH, such that passing proteins possess a net charge and can be separated by means of an appropriate ion exchanger. In this fashion, proteins from complex biological fluids can be separated for identification and study.
Patent EP-1848459-A4 (EP)
Inventor: GREENWALD RICHARD B
IPC: A61K47/48
Filed: 2006-01-31
Abstract: Procédé de préparation efficace de conjugués polymères, notamment de conjugués PEG-polypeptides ramifiés à grande échelle sans nettoyage par chromatographie à colonne des liens PEG activés afin de supprimer les impuretés.
Patent EP-1881934-A4 (EP)
Inventor: TEDFORD RICHARD A JR
IPC: B65D39/00
Filed: 2006-05-16
Abstract: Un couvercle est prévu pour servir de fermeture à un contenant à boisson ou à tout autre dispositif de distribution, ledit couvercle comprenant un bec de distribution qui permet de distribuer le contenu du contenant. Une patte de connexion souple s'étend autour d'au moins une partie périphérique du couvercle et comporte une extrémité fixe reliée à demeure au couvercle au niveau d'un premier endroit cintré de ce dernier et une extrémité libre reliée de manière frangible au couvercle par un onglet frangible situé au niveau d'un deuxième endroit cintré du couvercle. L'extrémité libre de la patte de connexion peut être détachée du couvercle par déchirement d'une ligne de perforation prévue dans la patte de connexion qui est radialement espacée vers l'extérieur de l'onglet frangible. De cette manière, le détachement de la patte de connexion du couvercle est effectué par une ligne de perforation discontinue parcourant la patte de connexion plutôt que par le rebord du couvercle, ce qui permet de détacher la patte de connexion du couvercle sans porter atteinte à l'intégrité du joint entre le couvercle et le gobelet. Un élément de fermeture peut être prévu à proximité de l'extrémité libre de la patte de connexion, cet élément pouvant être inséré de manière amovible dans le bec de distribution du couvercle dès lors que la patte de connexion est détachée du couvercle.
Patent EP-1942800-A4 (EP)
Title: System and method for concurrent transfer and processing and real time viewing of in-vivo images
Inventor: DAVIDSON TAL
IPC: G06T7/00
Filed: 2006-09-10
Abstract: Embodiments of the present invention provide a system and method for a concurrent transferring of an image stream gathered by an in-vivo sensing device, including creating a plurality of segments from at least a portion of the image stream and concurrently transferring the created segments. Other embodiments of the present invention provide and system and method for a concurrent processing of an image stream gathered by an in-vivo sensing device, including creating a plurality of segments from at least a portion of the image stream and concurrently processing the created segments.
Patent EP-1953178-A4 (EP)
Title: Process for producing aqueous dispersion of composite of poly(3,4-dialkoxythiophene) with polyanion
Inventor: MORITA YOSHIYUKI
IPC: C08K5/14
Filed: 2006-10-06
Abstract: The present invention provides a method for the production of an aqueous dispersion containing an electroconductive polymer component which enables electroconductive thin films which are outstanding in their transparency and electroconductivity to be formed, together with the aqueous dispersion obtained by said method. This method includes a stage in which a 3,4-dialkoxythiophene is polymerized in an aqueous solvent using an oxidizing agent in the presence of a polyanion and, in this stage, said oxidizing agent is added by the dropwise addition of a solution or dispersion containing said oxidizing agent to the reaction solution or, alternatively, in the polymerization stage, the alkali metal ion concentration in the reaction liquid is maintained at no more than 400 ppm.
Patent EP-2179588-A4 (EP)
Title: Encoding method and apparatus for efficiently encoding sinusoidal signal whose magnitude is less than masking value according to psychoacoustic model and decoding method and apparatus for decoding encoded sinusoidal signal
Inventor: LEE NAM-SUK
IPC: H04N7/24
Filed: 2008-05-27
Abstract: Provided are an encoding method and apparatus for efficiently encoding a sinusoidal signal whose magnitude is less than a masking value according to a psychoacoustic model, a decoding method and apparatus for decoding an encoded sinusoidal signal, and a computer-readable recording medium having recorded thereon a program for executing the encoding method/the decoding method. By using a particular code indicating that the magnitude of a first sinusoidal signal is less than a masking value according to a psychoacoustic model to encode the first sinusoidal signal, difference coding for a third sinusoidal signal of a next frame, which is connected to the first sinusoidal signal, is performed using a sinusoidal signal or sinusoidal signals selected according to a method to use the particular code, and a decoding apparatus obtains a sum with a transmitted difference using the selected sinusoidal signal(s).
Patent EP-2193982-A4 (EP)
Title: Automobile body structure
Inventor: TANAKA YUKIO
IPC: B62D25/20
Filed: 2008-09-30
Abstract: It is an object of the present invention to prevent a vehicle door from protruding into a vehicle cabin when a collision load is applied to the door from a lateral side thereof, and to reduce costs that are required for measures to prevent the door from protruding into the vehicle cabin. 
The present invention is directed to a vehicle body structure in which a collision load (F) applied to one of vehicle doors from a lateral side thereof is received by a load receiving member (20) of a body via an impact beam (2) and a door box (4) of the door and is transmitted from the load receiving member (20) to a cross member (10). The load receiving member (20) includes a load receiving pipe (30) that is formed as a linear tubular body disposed between the right and left doors so as to extend in a vehicle widthwise direction and is capable of transmitting the collision load from the door box (4) of one of the doors to a door box of the other of the doors, and connecting portions (40) that are capable of supporting the load receiving pipe (30) at positions adjacent to the right and left doors and connecting the load receiving pipe to the cross member.
Patent EP-2201932-A4 (EP)
Title: Multi-component hair dye composition
Inventor: FUKUHARA MASAKI
IPC: A61Q5/08
Filed: 2008-10-10
Abstract: Disclosed is a multi-component hair dye composition excellent in bleaching property and dyeing property.  A multi-component hair dye composition including components (a), (b) and (c), wherein the components are mixed upon use: 
(a) one or more kinds of glycylglycine derivative represented by general formula (1) and having two or three amino acid residues, or salts thereof; 
[wherein X represents a bivalent hydrocarbon group having 1 to 4 carbon atoms which may be substituted with a hydroxyl group, or an amino acid residue; 
Y represents an amino acid residue, or a bivalent group represented by general formula (2): 
(wherein symbol -* represents a bond that binds to an adjacent carbonyl group or oxygen atom); 
R represents a hydrogen atom, or a monovalent hydrocarbon group having 1 to 4 carbon atoms in which the hydroxy group may be substituted; and 
m and n each represent 0 or 1, provided that when both m and n represent 1, X is not an amino acid residue];  
(b) an alkali agent; and 
(c) an oxidizing agent.
Patent EP-0094398-A4 (EP)
Title: Dyestuff composition for histological examinations.
Inventor: BALOGH GYORGY
IPC: C07C39/08
Filed: 1982-11-18
Abstract: The invention relates to a new dyestuff composition for histological examinations, which comprises (1) a product formed by the interaction of one molar proportion of one or more thionine dyestuffsselected from thionine (Colour Index 52,000), toluidine blue (Colour Index 52,040) and dimethyl thionine (Azur A) with at least 0.2 molar proportion of resorcine at elevated temperature, (2) 0.5 to 2 moles of a dyestuff "A", calculated for one mole of the thionine dyestuff interacted with resorcine, and (3) 0.5 to 2 moles of a dyestuff "B", calculated for one mole of the thionine dyestuff interacted with resorcine, wherein dyestuff "A" and dyestuff "B" are alkaline dyestuffs different in colour and pH, and both dyestuff "A" and dyestuff "B" can be mixtures of alkaline dyestuffs similar in colour and pH. The new dyestuff compositions according to the invention enable one to perform a wide variety of hisotlogical examinations much more quickly, simply and safelyb than before, and can also be applied to detect histological changes which could not be detected before.
Patent EP-0135587-A4 (EP)
Title: Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis.
Inventor: RUTH JERRY L
IPC: C12Q1/68
Filed: 1984-02-22
Abstract: Defined sequence single strand oligonucleotides which have a length of fewer than 200 units, incorporate modified nucleotide units which are pyrimidine or purine-based, and which may have readily detectable reporter groups attached to substituents on the modified nucleotide units thereof. Each reporter group is attached to the base of the respective nucleotide unit at a sterically tolerant site thereon, exemplified by the C-5 position of pyrimidine-based nucleotides and the C-8 position of purine-based nucleotides. Such oligonucleotides are useful in identification, localization, isolation and/or detection of complementary nucleic acid sequences of interest in cellular or cell-free systems. Also disclosed is a process for the chemical synthesis of single strand oligonucleotides having a predetermined number of modified pyrimidine and/or purine-based nucleotide units in predetermined sequence, to the bases of which readily detectable reporter groups are attached at sterically tolerant sites through substituents thereon, either prior to or after incorporation of such units into the oligonucleotide chain. Novel nucleosides useful in the chemical synthesis of labeled, defined sequence single strand oligonucleotides are also disclosed.
Patent EP-0338018-A4 (EP)
Title: Lubricated spline joint
IPC: F16N29/00
Filed: 1987-12-17
Abstract: A lubricated spline joint (30) for providing a viscous damping function includes a first member (32) defining an internal spline (62), a second member (34) defining an external spline (64) engaged therewith, a seal ring (76) between the members (32, 34) at one end of the splines, and a radially inwardly facing chamber (80) at the other end which is exposed to lubrication fluid. The improvement features an internal barrier (84) for assuring a fixed internal radius R and thus a preselected centrifugal pressure head of the fluid mass (86) in the chamber (80) and about the splines, and a plurality of venting passages (94) located radially outwardly of the radius R for continually exhausting fluid from the splines as a result of centrifugal force so that fresh and/or less aerated fluid is circulated through the splines.
Patent EP-0355109-A4 (EP)
Inventor: LOBB KEVIN JOHN
IPC: C02F9/00
Filed: 1988-04-22
Abstract: La présente invention se rapporte à un procédé et à un système permettant de séparer par aération un composant, tel que du cyanure, à partir d'un liquide contenant ce composant. Ledit procédé consiste à faire passer le liquide à travers un réseau de colonnes d'aération disposées en paliers, de sorte que le liquide s'écoulant depuis une colonne d'aération dans un premier palier soit divisé en au moins deux courants qu'on introduit dans des colonnes d'aération séparées dans un second palier successif. Ledit procédé consiste également à faire passer de l'air à travers les colonnes d'aération à contre courant du liquide, afin d'entraîner dans l'air au moins une partie du composant, de façon à pouvoir séparer du liquide au moins cette partie.
Patent EP-0309571-A4 (EP)
Title: Wheeled luggage with auxiliary bag carrying feature.
Inventor: KING WILLIAM L
IPC: A45C13/30
Filed: 1988-04-14
Abstract: Luggage of the type adapted to maintain articles of clothing, business materials and the like is disclosed having roller means along a lower edge thereof and a modular handle unit adapted to be extended away from the luggage to provide a pull handle therefor and further including an elongated strap adapted to be extended around an auxiliary piece of luggage to piggyback the auxiliary piece of luggage on the main piece of luggage.
Patent EP-0365560-A4 (EP)
Title: Riboflavin producing strains of microorganisms, method for selecting, and method for fermentation
IPC: C12N15/04
Filed: 1988-06-02
Abstract: Strains of yeast of the species Candida famata are disclosed which can produce 10 grams of riboflavin per liter in 6 days, and in particular, strains identified by ATCC Accession Nos. 20849 and 20850. Riboflavin yields of more than 20 grams per liter in 200 hours have been achieved. Strains of the present invention have increased sensitivity to iron inhibition of flavinogenesis and have enhanced riboflavin production per cell at increased iron concentrations in the fermentation medium.
Patent EP-0441865-A4 (EP)
Title: Orbital and/or reciprocal machining with a viscous plastic medium
IPC: B24B1/00
Filed: 1989-10-24
Abstract: A method of honing, polishing, reducing, or otherwise abrading, workpiece surfaces utilizing a visco-elastic abrasive medium (18) in situ between the workpiece (10) and a displacer member (14). Said displacer member (14) having surfaces in a facing spaced relationship to the surfaces of said workpiece (10) to be abraded to thereby form a media chamber between the surfaces of said workpiece (10) to be machined and said displacer member (14). The visco-elastic abrasive medium (18) is deposited within said media chamber. Thereafter, one or more forms of relative motion between the workpiece (10) and displacer member (14) forces flow of the medium (18) across the workpiece surface to be abraded thereby effecting the abrasion as desired.
Patent EP-0593419-A4 (EP)
Title: Inhibitors for glycosaminosyl transferase-v
Inventor: PIERCE JAMES MICHAEL
IPC: C12N9/99
Filed: 1989-11-21
Abstract: Synthetic glycosaminosyl transferase-V acceptors and inhibitors are disclosed. Minimal trisaccharide inhibitors and acceptors specific for GnT-V, which is associated with the ability of cells to metastasize are useful, in diagnosis and treatment of conditions characterized by metastatic cells.
Patent EP-0468999-A4 (EP)
Title: Cerebral biopotential analysis system and method
IPC: A61B5/374
Filed: 1990-03-13
Abstract: Disclosed is a real time cerebral diagnostic apparatus and method for quantitatively evaluating, in a noninvasive manner, cerebral phenomena such as the depth and adequacy of anesthesia pain responses during surgical stress, acute cerebral ischemia, level of consciousness, degree of intoxication and ongoing normal and abnormal cognitive processes. A suitable electrode and amplifier system is used to obtain high resolution biopotentials from the regions of interest. Surface electroencephalographic (EEG) signals are filtered to allow the acquisition of frequencies between 2 and 500 Hz, then digitized and transmitted over a high speed serial line to a host computer where a 32 second long signal is divided into 128 consecutive 0.25 second intervals. Digital EEG data from unipolar leads is normalized and the dynamic phase and density relations within the signal are then characterized by estimating the third-order autocorrelation function or autobispectrum using either a frequency domain, or parametric approach. Paired EEG data from corresponding left and right hemisphere leads is used to characterize the dynamic phase and density relations between hemispheres by estimating the third order crosscorrelation function or crossbispectrum using either frequency domain or parametric techniques. Under certain specific filtering circumstances the power spectrum and crosspower spectrum are also computed. A reference clinical database is used to identify frequency pairs most sensitive to particular interventions or diagnostic states of interest. The values at these frequency pairs are then extracted from the patient's autobicoherence, autobispectral density, autobiphase, crossbicoherence, crossbispectral density, and crossbiphase arrays. The ensemble of values for the particular diagnostic determination is used to compute an index which serves as the diagnostic criterion by which the patient's state is judged. Any diagnostic index can be continuously displayed on a graphics terminal for real-time diagnostic monitoring or can be sent to a hard copy device to generate reports for the medical record.
Patent EP-0484420-A4 (EP)
Title: Undercut free constant velocity joint
IPC: F16D3/224
Filed: 1990-06-22
Abstract: A constant velocity universal joint for transmitting driving torque between rotative members, such universal joint including a hub fixed to one of the rotative members and an outer joint member attached to the hub, an inner joint member attached to another one of the rotative members and a ball containing cage positioned between the outer joint member and the inner joint member. The balls are engaged in ball races positioned in the outer joint member and in the inner joint member. The ball races are sloped so as to provide maximum material at the location of highest stress, the major ball races being of the undercut free design.