baber/WOPTO huggingface dataset:
Patent EP-3476865-A1 (EP)
Inventor: SHEN YUELEI
IPC: C12N15/85
Filed: 2017-06-27
Abstract: Provided is a method for preparing a PD-1 gene-modified humanized animal model. The method utilizes the CRIPSR/Cas9 technique to replace partial fragments of a mouse PD-1 gene with fragments of a human PD-1 gene using homologous recombination by constructing a targeting vector, thereby preparing a gene-modified humanized mouse. This mouse can normally express a PD-1 protein containing the functional domain of the human PD-1 protein, and can be used as an animal model for mechanism research regarding PD-1, PD-L1 and other signals, for screening regulators, and for toxicological research. The method has an important and high application value in studies on functions of the PD-1 gene and in the development of new drugs.
Patent EP-3559544-A1 (EP)
Inventor: KÜNZEL ROLAND
IPC: F21V8/00
Filed: 2017-12-18
Abstract: Die vorliegende Erfindung betrifft einen Schichtaufbau (S) für ein beleuchtbares Bedienelement umfassend oder bestehend aus den folgenden Schichten in der angegebenen Reihenfolge: A) ein lichtleitendes Flächenelement (3) in das von einer Lichtquelle (4) Licht über wenigstens eine seiner Stoßkanten einkoppelbar ist, wobei das Licht innerhalb des lichtleitenden Flächenelements (3) lateral propagiert und auf seiner der Symbolschicht (1) zugewandten Flachseite zumindest abschnittsweise ausgestrahlt wird; B) gewünschtenfalls eine transparente Zwischenschicht (2); C) eine zweite Symbolschicht (1) umfassend wenigstens ein Symbol; D) gewünschtenfalls eine Schutzschicht (6). Die Erfindung betrifft ferner die Herstellung eines solchen Schichtaufbaus (S), ein beleuchtbares Dekorelement mit einem solchen Schichtaufbau (S), sowie die Verwendung des Dekorelements und des Schichtaufbaus (S).
Patent EP-3566389-A1 (EP)
Inventor: VEENINGEN MEILOF GEERT
IPC: H04L9/08
Filed: 2017-12-28
Abstract: According to an aspect, there is provided a first node for use in a system, wherein the first node is configured to determine a plurality of keys for enabling a computation by a plurality of worker nodes in the system, wherein the computation comprises a plurality of computation parts, wherein the plurality of computation parts comprises one or more types of computation part, and wherein an output from one computation part to another computation part is a shared block; and publish the determined plurality of keys for access by at least one input node in the system, the plurality of worker nodes, and at least one recipient node in the system; wherein the plurality of keys comprises a computation part prove key for each part of the computation; a computation part verification key for each part of the computation; a shared block commitment generation key for each shared block; an input commitment generation key for each input node and computation part combination; and an output commitment generation key for each recipient node and computation part combination. A corresponding method of operating a first node is also provided.
Patent EP-3577483-A1 (EP)
Inventor: EDGE STEPHEN WILLIAM
IPC: H04W64/00
Filed: 2017-12-14
Abstract: Disclosed are methods for aiding a mobile device in the acquisition of positioning reference signals (PRSs) transmitted in a cellular network in support of OTDOA positioning. In one implementation, a mobile device receives an offset parameter from a location server indicative of a difference in timing between transmission of a first PRS positioning occasion for a reference cell and transmission of a second PRS positioning occasion for a neighboring cell that supports multiple PRS configurations, where the second PRS positioning occasion is for a PRS configuration with a longest periodicity. The mobile device may determine an expected timing of PRS positioning occasions for other PRS configurations for the neighboring cell based on the offset parameter and may measure a Reference Signal Time Difference for the neighboring cell using the expected timing.
Patent EP-3419845-A1 (EP)
Inventor: BERGMANN LUTZ
IPC: B60J10/70
Filed: 2017-12-21
Abstract: Die Erfindung betrifft eine Kraftfahrzeuganordnung (10), umfassend eine Windschutzscheibe (12), eine an einer unteren Berandung (14) der Windschutzscheibe befestigte Profilleiste (20) und ein an die Windschutzscheibe angrenzendes Abdeckbauteil (34), wobei die Profilleiste oder das Abdeckbauteil einen zwischen Windschutzscheibe und Abdeckbauteil wirksamen Dichtungsabschnitt (32) aufweist, der gemeinsam mit einer Außenseite (36) der Windschutzscheibe und einer Außenseite (40) des Abdeckbauteils einen Teil der Außenfläche (42) des Kraftfahrzeugs bildet, wobei ein Zusatzbauteil (48) vorgesehen ist, das Teil einer Kraftfahrzeugkarosserie (50) ist oder mit dieser verbunden ist, wobei das Zusatzbauteil einen ersten Befestigungsabschnitt (52) und die Profilleiste einen zweiten Befestigungsabschnitt (66) aufweist, wobei das Abdeckbauteil einen Halteabschnitt (46) aufweist, der zwischen die Befestigungsabschnitte (52, 66) einführbar oder eingeführt ist und dort befestigbar oder befestigt ist. Die Erfindung betrifft ferner eine Vormontageinheit, eine Profilleiste und Verfahren zur Montage einer Kraftfahrzeuganordnung.
Patent EP-3555622-A1 (EP)
Inventor: DAY WILLIAM
IPC: C12Q1/28
Filed: 2017-12-18
Abstract: Methods and systems are provided for quantitative immunohistochemistry (IHC) of a target protein molecule including a secreted target protein molecule. The method comprises introducing to the sample: a primary antibody specific for the target protein molecule; a secondary antibody conjugated to a secondary antibody enzyme, the secondary antibody is specific for the primary antibody; a tyramide conjugated with a tyramide hapten, wherein the secondary antibody enzyme catalyzes deposition of the tyramide hapten onto the sample; a tertiary antibody conjugated with a tertiary antibody enzyme, the tertiary antibody is specific for the tyramide hapten; and a chromogen, wherein the tertiary antibody enzyme catalyzes a reaction with the chromogen to make the chromogen visible. The chromogen is visible as a punctate dot using microscopy.
Patent EP-3559223-A1 (EP)
Title: Gene editing of pcsk9
Inventor: MAIANTI JUAN PABLO
IPC: C12N9/22
Filed: 2017-12-22
Abstract: Provided herein are systems, compositions, and methods of introducing loss-of- function mutations in to protein factors involved in the LDL-R-mediated cholesterol clearance pathway, e.g., PCSK9, APOC3, LDL-R, or IDOL. Loss-of-function mutations may be introduced using a CRISPR/Cas9-based nucleobase editor described in. Further provided herein are compositions and methods of treating conditions related to high circulating cholesterol levels.
Patent EP-3493842-A1 (EP)
Title: Biomatériaux pour moduler des réponses immunitaires
Inventor: MOONEY DAVID J
IPC: A61K39/39
Filed: 2017-08-02
Abstract: La présente invention concerne des procédés et des compositions pour induire une réponse immunitaire à un antigène, tel que des antigènes cancéreux et microbiens.
Patent EP-3500685-A1 (EP)
Inventor: BLATTMAN JOSEPH
IPC: C12Q1/68
Filed: 2017-08-14
Abstract: L'invention concerne des procédés pour l'incorporation de codes-barres en nœud papillon uniques dans une nanostructure d'origami acide nucléique (Fig.1). En particulier, l'invention concerne des procédés qui facilitent l'appariement et l'analyse d'acides nucléiques provenant de cellules individuelles à l'aide, par exemple, d'un séquençage de nouvelle génération à haut débit.
Patent EP-3399737-A1 (EP)
Inventor: CHEN XIAOLIANG
IPC: H04N5/225
Filed: 2017-01-17
Abstract: The present invention relates to the field of video recording technologies, and in particular, to an illumination processing method and apparatus. A liquid crystal panel is disposed between a photosensitive sensor and a lens assembly, and an incident light from the lens assembly reaches the photosensitive sensor after passing through the liquid crystal panel. The method includes: determining a highlight region on a first image captured from the photosensitive sensor; and turning down light transmittance of each pixel in an adjustment region on the liquid crystal panel, wherein the adjustment region is corresponding to the highlight. According to the illumination processing method and apparatus provided in embodiments of the present invention, occurrence of a highlight blooming phenomenon can be avoided as much as possible, thereby avoiding loss of valid image information.
Patent EP-3507840-A1 (EP)
Inventor: MAJKIC GORAN
IPC: H01B12/00
Filed: 2017-08-29
Abstract: A superconductor tape and method for manufacturing, measuring, monitoring, and controlling same are disclosed. Embodiments are directed to a superconductor tape which includes a superconductor film overlying a buffer layer which overlies a substrate. In one embodiment, the superconductor film is defined as having a c-axis lattice constant higher than 11.74 Angstroms. In another embodiment, the superconductor film comprises BaMO 3 , where M = Zr, Sn, Ta, Nb, Hf, or Ce, and which has a (101) peak of BaMO 3  elongated along an axis that is between 60° to 90° from an axis of the (001) peaks of the superconductor film. These and other embodiments achieve well-aligned nanocolumnar defects and thus a high lift factor, which can result in superior critical current performance of the tape in, for example, high magnetic fields.
Patent EP-3509724-A1 (EP)
Inventor: SUTTERLIN WILLIAM RUSTY
IPC: C11B13/02
Filed: 2017-09-06
Abstract: Provided are methods, processes and systems for treating a soapstock. In alternative embodiments, provided are systems and methods for treating a soapstock to generate free fatty acids and/or fatty acid derivatives, e.g. fatty acid alkyl esters. In alternative embodiments, provided are systems and methods for realizing the full fatty acid yield of a soapstock by first converting substantially all of the saponifiable material in a soapstock to salts of fatty acids (soaps) and acidulating the soaps to generate free fatty acids and/or fatty acid derivatives, e.g. fatty acid alkyl esters, wherein the soapstock comprises soaps and saponifiable lipids, e.g. glycerides and/or phospholipids, and the generating of free fatty acids and/or fatty acid is achieved.
Patent EP-3533822-A1 (EP)
Inventor: SAUL CYRO KETZER
IPC: C08J7/00
Filed: 2017-10-27
Abstract: The present invention describes a method for chemically and / or biologically activating the surface of originally inert polymeric materials. Activation of the polymer surface occurs by the physical incorporation of at least one linear long chain compound by the inert polymer in the presence of a solvent.
Patent EP-3532879-A1 (EP)
Inventor: TEKOLSTE ROBERT D
IPC: G02F1/136
Filed: 2017-10-25
Abstract: An eyepiece for projecting an image to an eye of a viewer includes a waveguide configured to propagate light therein, and a diffractive optical element optically coupled to the waveguide. The diffractive optical element includes a plurality of first ridges protruding from a surface of the waveguide. Each of the plurality of first ridges has a first height and a first width. The diffractive optical element further includes a plurality of second ridges. Each of the plurality of second ridges protrudes from a respective first ridge and has a second height greater than the first height and a second width less than the first width. The diffractive optical element is configured to diffract a first portion of the light propagating in the waveguide toward the eye, and to diffract a second portion of the light propagating in the waveguide away from the eye.
Patent EP-3548791-A1 (EP)
Inventor: Kármán Balázs 
IPC: F16M11/04
Filed: 2017-09-18
Abstract: A top bracket (10) for tripods provided with a center opening (22) and comprises respective leg supports (12, 13, 14), the opening (22) has a cylindrical upper section (27), and further comprises an adjustable fastening means that fixes the position of said top plate (30) when being inserted and allows removal of the top plate (30) when loosened, wherein a spherical cavity (29) is provided in the opening (22) starting under the cylindrical upper section (27) which has a height much smaller than the height of the cylindrical cavity (29) under it, and the diameter of the spherical cavity (29) increases under the cylindrical upper section (27) until at a central height region of the body (11) it takes the highest equatorial diameter (D) and narrows down in downward direction, and the opening (22) is designed to receive either the cylindrical top plate (30) with a cylindrical side surface at its upper part (31) or to receive a leveling support (40) that has a spherical side (43) that fits in the spherical cavity (29), and the top bracket (10) comprises a mechanism that allows insertion and removal of the leveling support (40) in the opening (22).
Patent EP-3556018-A1 (EP)
Inventor: PETROV DMITRY
IPC: H03L7/06
Filed: 2017-12-04
Abstract: According to a first example aspect there is provided a charge pump circuit that includes a first chopper circuit configured to switch first and second chopper circuit outputs between first and second chopper circuit inputs at a chopping frequency, wherein successive input signals at the first chopper circuit input are output alternatively at the first and second chopper circuit outputs in successive cycles of the chopping frequency and successive input signals at the second chopper circuit input are output alternatively at the second and first chopper circuit outputs in successive cycles of the chopping frequency. A differential charge pump is configured to receive the signals output from the first and second chopper circuit outputs and produce corresponding first and second charge pumped signals.
Patent EP-3535187-A1 (EP)
Inventor: PANTALONE GIULIA
IPC: B64C11/18
Filed: 2017-12-15
Abstract: An aerial vehicle is provided including rotor units connected to the aerial vehicle, and a control system configured to operate at least one of the rotor units. The rotor unit includes rotor blades, wherein each rotor blade includes a surface area, and wherein an asymmetric parameter is defined, at least in part, by the relationship between the surface areas of the rotor blades. The value of the asymmetric parameter is selected such that the operation of the rotor unit: (i) moves the rotor blades such that each rotor blade produces a respective vortex and (ii) the respective vortices cause the rotor unit to produce a sound output having an energy distribution defined, at least in part, by a set of frequencies, wherein the set of frequencies includes a fundamental frequency, one or more harmonic frequencies, and one or more non- harmonic frequencies having a respective strength greater than a threshold strength.
Patent EP-3588248-A1 (EP)
Inventor: HE GUANG
IPC: H04M1/60
Filed: 2017-07-28
Abstract: A headset, a terminal, and a control method are provided. The headset includes a connector of the headset configured to connect to a terminal, the connector of the headset includes at least one functional pin, and the headset further includes a sensor circuit and a logic control circuit. The sensor circuit is connected to a functional pin of the connector of the headset by using the logic control circuit. The sensor circuit is configured to: sense a wearing status of the headset, and output a trigger signal to the logic control circuit when the wearing status changes. The logic control circuit is configured to change, based on the trigger signal, a voltage value on the functional pin connected to the logic control circuit, to trigger the terminal to perform a target operation event based on a changed voltage value on the functional pin, where the target operation event is preset for the voltage value on the functional pin. A sensor may be added to the headset, and sensor information may be fed back to the terminal, to implement various new functions and improve user experience.
Patent EP-3605560-A1 (EP)
Inventor: KIM JI-SUNG
IPC: H01B7/02
Filed: 2017-03-30
Abstract: Provided is a power cable, particularly, an ultra-high voltage underground or submarine cable for long-distance direct-current transmission. More specifically, the present invention relates to a power cable, in which an insulating layer has high dielectric strength, an electric field applied to the insulating layer is effectively reduced, and particularly, a large void is suppressed from occurring in the insulating layer when the power cable is left at low temperatures for a long time until electric current is supplied thereto after installed in a low-temperature environment, thereby effectively preventing partial discharge, dielectric breakdown, etc. from occurring due to an electric field concentrated in the large void.
Patent EP-3602705-A1 (EP)
Inventor: MONROS SERGE V
IPC: F02P3/08
Filed: 2017-05-12
Abstract: Selon la présente invention, un fil de bougie d'allumage pour un moteur à combustion interne comporte un conducteur allongé avec un module de condensateur programmable disposé en ligne avec le conducteur allongé. Le module de condensateur programmable est configuré pour élever ou convertir la tension d'allumage normalement fournie par une bobine d'allumage en tension de plasma. Une bougie d'allumage selon l'invention est configurée de sorte que l'anode entourée par l'isolant comprenne ou soit remplacée par un module de conversion de tension conçu pour convertir la tension d'allumage en tension de plasma. Le module de conversion de tension est constitué d'un circuit à semi-conducteur, d'un matériau semi-conducteur composite ou d'un condensateur.
Patent EP-3611701-A1 (EP)
Inventor: XU JIU
IPC: G06T7/194
Filed: 2017-04-11
Abstract: To increase accuracy in extracting a foreground area while saving a user time and effort. Image obtaining means (100) of an image processing device (10) obtains an image including a background and an object. Element area setting means (102) sets, with respect to the image, a plurality of element areas respectively corresponding to a plurality of elements in the image. Overlapped area specifying means (103) specifies an overlapped area in which a degree of overlap of the element areas is greater than or equal to a predetermined value in the image. Foreground area extracting means (104) extracts a foreground area corresponding to the object from the image based on the overlapped area.
Patent EP-3600042-A1 (EP)
Inventor: XIAO YONGQIN
IPC: A61B6/10
Filed: 2017-09-30
Abstract: A system (100) includes one or more storage devices (150) storing a set of instructions and at least one processor (310) in communication with the storage device (150). When executing the instructions, the at least one processor (310) is configured to cause the system (100) to obtain a first operating state of an X-ray imaging device (110), and obtain a first input from a user via a terminal (130), the first input being associated with a second operating state of the X-ray imaging device (110). The at least one processor (310) may further cause the system (100) to determine whether the first input satisfies a switch condition. Upon a determination that the first input satisfies the switch condition, the at least one processor (310) may further cause the system (100) to transmit a first instruction to switch the X-ray imaging device (110) from the first operating state to the second operating state.
Patent EP-3636127-A1 (EP)
Inventor: FURUTA TAKAYUKI
IPC: A47L9/28
Filed: 2017-06-07
Abstract: Provided is a self-propelled vacuum configured so that obstacle avoidance operation can be efficiently performed and cleaning time can be shortened. A self-propelled vacuum 1 includes a laser range finder (LRF) 20 configured to sense the periphery of a vacuum body 2, and an up-down drive unit 22 configured to move the LRF 20 up and down between a protrusion position above the vacuum body 2 and a housing position in the vacuum body 2. The up-down drive unit 22 is driven to move the LRF 20 up and down.
Patent EP-3649837-A1 (EP)
Inventor: FRANKE GREGORY C
IPC: H05K5/02
Filed: 2017-07-06
Abstract: An example electronic device includes an outer housing, a shoulder connected to the outer housing, and a mounting assembly moveably coupled to the outer housing to mount a peripheral module. The mounting assembly has a rotatable arm biased to a first angular position. The rotatable arm is to remain in the first angular position when a first peripheral module is mounted, whereby the mounting assembly is moveable to extend the first peripheral module to a first clearance distance. The rotatable arm is rotatable to a second angular position in response to mounting a second peripheral module, whereby the mounting assembly is moveable to engage the rotatable arm against the first shoulder and to extend the second peripheral module to a second clearance distance that is less than the first distance.
Patent EP-3678367-A1 (EP)
Inventor: RYU JAEUK
IPC: H04N5/65
Filed: 2017-08-28
Abstract: A display device is disclosed. The display device of the present invention may comprise: a display panel; and a module cover positioned at a rear of the display panel, the module cover including: a flat plate portion corresponding to a rear surface of the display panel; and a side wall extended toward a front of the display panel from the flat plate portion, the side wall covering an edge of the display panel, wherein the flat plate portion includes: a flat plate portion first layer facing the display panel, the flat plate portion first layer positioned at the rear of the display panel; a flat plate portion second layer positioned at a rear of the flat plate portion first layer; and a flat plate portion third layer positioned at a rear of the flat plate portion second layer, and wherein a rigidity of the flat plate portion second layer is greater than a rigidity of the flat plate portion first and third layers.
Patent EP-3679051-A1 (EP)
Inventor: XIANG JIA-NING
IPC: A61P25/14
Filed: 2017-09-04
Abstract: A compound of Formula (I), pharmaceutically acceptable salts thereof, and individual enantiomers or diastereomers thereof are disclosed. Compositions and methods useful for treatment or suppression of diseases, developmental delays and symptoms related to oxidative stress are also disclosed.
Patent EP-3674865-A1 (EP)
Inventor: GAN YUANLI
IPC: G06F3/048
Filed: 2017-10-13
Abstract: Embodiments of this application provide a display processing method and an electronic device (40), to increase a width of a display object by changing a positional relationship between the display object and another display object, thereby providing a greater display width for a to-be-displayed character string. A main solution is: displaying, by an electronic device (40), a first display object and a second display object on a first screen based on a first positional relationship; in response to determining that a length of a to-be-displayed character string corresponding to the first display object is greater than a first width of the first display object on the first screen, stopping displaying the first screen (200); and displaying the first display object and the second display object on a second screen, where the first display object and the second display object on the second screen have a second positional relationship, the second positional relationship is different from the first positional relationship, and a second width of the first display object corresponding to the second positional relationship is greater than the first width (201).