baber/WOPTO huggingface dataset:
Patent DE-69313468-T2 (DE)
Inventor: MCGHEE WILLIAM
IPC: C07C265/04
Filed: 1993-12-17
Granted: 1998-02-05
Abstract: A process for preparing isocyanates comprising (a) contacting carbon dioxide and a primary amine in the presence of an aprotic organic solvent and a base selected from the group consisting of a phosphazene compound, an organic, nitrogenous base and mixtures thereof, wherein the organic, nitrogenous base selected from the group consisting of guanidine compounds, amidine compounds, tertiary amines, pyridine and mixtures thereof to produce the corresponding ammonium carbamate salt, and (b) reacting the ammonium carbamate salt with an electrophilic or oxophilic dehydrating agent to produce the corresponding isocyanate. A second embodiment comprises recovering the ammonium carbamate salt of step (a) prior to reacting the ammonium carbamate salt with an electrophilic or oxophilic dehydrating agent in the presence of an aprotic organic solvent and a base selected from the group consisting of a phosphazene compound, an organic, nitrogenous base and mixtures thereof, wherein the organic, nitrogenous base selected from the group consisting of guanidine compounds, amidine compounds, tertiary amines, pyridine and mixtures thereof.
Patent DE-69325896-T2 (DE)
Inventor: BRACCO UMBERTO
IPC: A61K/
Filed: 1993-05-19
Granted: 1999-12-02
Abstract: Lipid composition for cosmetic products based on a mixture of oils which are chosen so as to maintain a balance between all the classes of lipids capable of affording the essential fatty acids in optimum physiological proportions and of regulating the metabolism of these fatty acids with physiological responses which are desired for the skin. This composition is particularly suitable for aqueous cosmetic compositions such as, for example, creams or milks or anhyrous compositions for care of the body.
Patent DE-69327299-T2 (DE)
Inventor: ALEXANDRE NOEL
IPC: F24H9/12
Filed: 1993-10-27
Granted: 2000-07-20
Abstract: The invention relates to a valve for a heating installation or hot water installation comprising a valve body (2) and a controlled internal obturator (4), characterised in that the valve body (2) comprises at least one cylindrical portion equipped with at least one orifice (5) and in that the cylindrical portion comprises a connection sleeve (6) surrounding the cylindrical portion (3) and defining a circulation chamber (7). The invention also relates to a hot water installation or central heating installation and to a radiator having such a valve. <IMAGE>
Patent DE-69331292-T2 (DE)
Inventor: YAMAMOTO IWAO
IPC: G06F9/48
Filed: 1993-01-22
Granted: 2002-06-13
Abstract: An electronic apparatus (10) which includes a CPU (1), a ROM (2), a RAM (3), an input port (4), a data bus (5), an address bus (6), a patching portion address register (7) and a patching interrupt vector register (8) which are connected to the data bus (5), a comparator (9) which compares a coincidence with the address stored in the address register (7) and an address on the address bus (6) and supplies an interrupt to an interrupt control portion of the CPU (1) which is also supplied with other interrupts for other processing. Further, an external storage device (20), connected to the input port (4), supplies a main program bug patching information which is stored in the RAM (3), which includes a stack area (32) in which there are saved data written in the address register (7) and the patching interrupt register (8), so that patching of program bugs can be carried out even during an interrupt. <IMAGE>
Patent DE-69331522-T2 (DE)
Inventor: GUHA SUBHENDU
IPC: H01L31/20
Filed: 1993-06-23
Granted: 2002-08-29
Abstract: Substrate temperatures are maintained above 400 DEG  C. During the microwave energized glow discharge deposition of Group IV semiconductor materials. The substrate temperature range provides for the preparation of materials having improved electrical properties. Cell efficiency of a photovoltaic device of the p-i-n type is significantly improved by depositing the intrinsic layer using a microwave generated plasma and a substrate temperature in excess of 400 DEG  C. Maximum cell efficiency occurs for depositions carried out in the range of 400 DEG -500 DEG  C.
Patent DE-69401140-T2 (DE)
Inventor: BUREAU JACQUES
IPC: A62C3/16
Filed: 1994-02-25
Granted: 1997-04-03
Abstract: Device of the type comprising a complex of fibrous and/or textile elements assembled by adhesive bonding. According to the invention, the various elements (4, 5) are assembled using an active refractory adhesive (6), which holds up to approximately 1300@C, and includes components and active additives containing chemically bound water which are stable at temperatures less than 80@C. Application to protecting cable ducts. <IMAGE>
Patent DE-69402548-T2 (DE)
Inventor: EDWARDS CARL
IPC: A61P43/00
Filed: 1994-05-25
Granted: 1997-07-17
Abstract: The present invention relates to compounds of the formulawhereinX is N3, NH2, NHR, N(R)2, CN, SH, SR, or OR1; R is C1-C4 alkyl or (CH2)n-phi; n is an integer 0, 1, 2, 3 or 4; phi is a phenyl group unsubstituted or substituted with from 1 to 3 substituents, each substituent is independently selected from the group consisting of C1-C4 alkyl, C1-C4 alkoxy, halogen, CF3, OCF3, OH, CN, NO2 or NH2; R1 is C1-C4 alkyl or (CH2)m-NR2R3; m is an integer 1, 2, 3 or 4; R2 and R3 are each independently C1-C4 fluorinated akyl or cycloalkyl;The X substituent on the cyclopentanyl ring is in the TRANS configuration relative to the bicyclic substituent;Y is nitrogen;Z1 and Z2 are each independently hydrogen, halogen or NH2; and---- represents a singe or double bond;or pharmaceutically acceptable salts thereof, compositions comprising such compounds, and methods of treatment comprising administering of such compounds.
Patent DE-69407181-T2 (DE)
Inventor: WESSEL THOMAS
IPC: C08L25/00
Filed: 1994-01-21
Granted: 1998-06-10
Abstract: A composition of matter comprising: A) from 25 to 90 parts by weight of a syndiotactic, vinylaromatic thermoplastic resin, B) from 1 to 50 parts by weight of a rubbery, impact absorbing domain forming polymer, C) from 0.1 to 30 parts by weight of a nucleator for the syndiotactic, vinylaromatic thermoplastic resin, D) from 0 to 90 parts by weight of an mineral, glass, ceramic, polymeric or carbon reinforcing agent, and E) from 0 to 90 parts by weight of one or more polyarylene ethers or polar group modified polyarylene ethers.
Patent DE-69410273-T2 (DE)
Inventor: MUCKENFUHS DELMAR
IPC: B65D83/08
Filed: 1994-07-25
Granted: 1998-09-24
Abstract: The present invention pertains to improved pop-up dispensing systems in which edge portions of adjacent towels are non-parallel when the individual towel sheets are interleaved and folded. This new configuration provides improved pop-up dispensing reliability by providing a predictable, repeatable separation process. The overlapped area formed by the overlapping end edges is tapered such that there is a point across the sheet width with the greatest overlap in the direction of the pulling force and a point across the sheet width with the least overlap in the direction of the pulling force. This configuration allows the area of maximum overlap to pull the next sheet through the dispensing aperture at the same time that the sheet separation process is starting to take place at the area of least overlap. The separation process begins at the point of least overlap and proceeds across the overlapping area along a "separation front" toward the point of greatest overlap. When the overlapping area is reduced to the extent that there is insufficient overlapping area to sustain the shear forces exerted, complete separation of the two sheets will occur. The area of overlap, length of the separation front, and amounts of overlap at the point of greatest overlap can all be tailored to provide desired separation characteristics for a particular aperture size, substrate, moistening agent, and moisture loading.
Patent DE-69426570-T2 (DE)
Inventor: CHO YOUNG W
IPC: A61K9/113
Filed: 1994-11-03
Granted: 2001-08-23
Abstract: A pharmaceutical composition comprises microparticles in micell. The microparticles contain at least one pharmaceutically-active agent, at least one water soluble or miscible phospholipid, at least one lipid soluble or miscible phospholipid, at least one non-ionic surfactant having an HLB value of about 15 or greater, at least one non-ionic surfactant having an HLB value of about or less, and at least one water soluble or miscible sterol compound. The microparticles are suspended in at least one fatty acid having a chain length of C14 or less. The composition may optionally contain at least one fatty acid having a chain length of C16 or greater in a concentration of about 5 w/v % or less. The composition is prepared by admixing the pharmaceutically-active agent, phospholipids, surfactants, and sterol, micronizing the admixture to form microparticles, and suspending the microparticles in at least one fatty acid of chain length of C14 or less to form microparticles in micell. The invention may be useful in the oral administration of drugs and other therapeutic agents, as well as for the trans-umbilico-dermal administration of such drugs and therapeutic agents.
Patent DE-69429092-T2 (DE)
Inventor: BHAT M
IPC: C07K16/28
Filed: 1994-08-02
Granted: 2002-07-11
Abstract: Methods are provided for inducing cell death in B-cells, including neoplastic B-cells, by employing reagents that bind to a B-cell epitope. Particularly, antibodies specific for the marker can be administered to a host to induce death in B-cells to which the antibodies bind or can be used in ex vivo clinical situations to selectively remove B-cells. A B-cell specific oligosaccharide epitope useful as a B-cell marker has been identified. The ligand being recognized on B lymphocytes has no apparent similarities to any of the known pan-B cells markers. In addition, proteins which specifically bind the disclosed epitope are provided. Human monoclonal antibody 216, which recognizes this B-cell epitope, is cytotoxic to B-cells and binds all CD19+ and CD20+ B lymphocytes in human peripheral blood and spleen. Furthermore, MAb 216 does not distinguish B cells by the isotype expressed, binding IgG+ and IgM+ cells with equal intensity, and also bind all B cells regardless of their CD5 expression. Methods to inhibit neoplastic B-cell growth by administering a B-cell-cytotoxic protein are presented. These products and methods find use in diagnosis and therapy.
Patent DE-69429370-T2 (DE)
Inventor: LANCASTER JOHN EDWARD
IPC: E04D3/08
Filed: 1994-09-16
Granted: 2002-07-18
Abstract: An end cap (74) for ducted plastics panels (72) comprises a channel section member (80) having an intended upper side (82) and an intended lower side (83), the upper side including a co-extruded gasket, whereby when the end cap is pushed onto a plastics panel, the gasket lies on the panel surface to limit passage of water past the gasket. Extending upwardly from the upper side wall of the channel section is a rail baffle (88).
Patent DE-69432508-T2 (DE)
Inventor: JACOBSEN STEPHEN C
IPC: A61M5/142
Filed: 1994-11-22
Granted: 2003-11-13
Abstract: A volumetric pump for administering intravenous fluids to a patient comprises a housing having an elongate cavity therein with an open and a closed end. A resilient sheet of material having a centrally-located aperture covers the open end, and a pump shaft is slidably disposed through the aperture to form a sphincter seal therebetween. An inlet conduit leading from a fluid source (an IV bag) passes through the housing into the cavity near the open end thereof, and an outlet conduit leading to a fluid sink (the patient) passes through the housing from the cavity near the closed end thereof. The shaft is driven back and forth in reciprocating motion inwardly and outwardly of the cavity to produce, respectively, a positive pressure forcing fluid out of the outlet conduit to the fluid sink, and a negative pressure forcing fluid from the fluid source through the inlet conduit. <MATH>
Patent DE-69500634-T2 (DE)
Inventor: KEOGH MICHAEL JOHN
IPC: C08K5/00
Filed: 1995-03-28
Granted: 1998-01-08
Abstract: An article of manufacture comprising, as a first component, a plurality of electrical conductors, each surrounded by one or more layers of a mixture comprising one or more polyolefins and the reaction product of a compound containing a sterically hindered amine or phenol and a quinone compound, and, as a second component, hydrocarbon cable filler grease within the interstices between said surrounded conductors.
Patent DE-69501591-T2 (DE)
Inventor: MORELLI LORENZO
IPC: A01N63/00
Filed: 1995-05-18
Granted: 1998-06-10
Abstract: The present invention concerns Lactobacillus strains and pharmaceutical compositions containing them.
Patent DE-69505890-T2 (DE)
Inventor: SUZUKI NORITAKE
IPC: G09G3/30
Filed: 1995-06-07
Granted: 1999-05-12
Abstract: An electron-beam generating device, in which a number of cold cathode elements are matrix-wired, as well as a method of driving the device, is applied to an image forming apparatus. Statistical calculations are performed in advance with regard to a required electron-beam output, and loss produced in the matrix wiring is analyzed. Drive signals are corrected by deciding optimum correction values based upon the analytical results. As a result, when rows of the matrix are driven successively row by row, the intensity of the outputted electron beams can made accurate for any driving pattern. <IMAGE>
Patent DE-69512808-T2 (DE)
Inventor: PALACIOS PELAEZ RICARDO
IPC: A61K39/00
Filed: 1995-02-02
Granted: 2000-06-15
Abstract: Fimbriae adhesins have a molecular weight of 2x10<5> and 2x10<7> Da, and comprise 90-95% protein and 1-3% sugar. Type 1 fimbriae show 5 different protein fractions of 14-20 kDa, most of which are associated to carbohydates. Type P fimbriae also include 5 different protein fractions of 14-20 kDa, one of the majority ones being associated to carbohydrates. The process comprises: culturing E. coli strains CECT 4484 and CECT 4485; collecting the sediment by centrifugation, resuspending it in physiological saline and homogenizing it; centrifuging the homogenate collecting the supernatant, which is subjected to saline precipitation, reconstituting the precipitate and dialyzing the solution; treating the dialyzate with sodium deoxcholate and, subjecting the product to two successive chromatographies with Sephacryl S-200 and Sepharose 4B. Use in treating and preventing infections of the urinary tract produced by fimbriated E. coli.
Patent DE-69513420-T2 (DE)
Inventor: LOFTUS JAMES
IPC: D04H1/54
Filed: 1995-12-18
Granted: 2000-05-31
Abstract: A method for producing mineral fibers includes centrifuging mineral fibers from one or more rotary mineral fiber spinners to establish one or more downwardly moving veils of mineral fibers positioned above a collecting surface, centrifuging organic fibers from molten organic material using one or more rotary organic fiber spinners to establish one or more downwardly moving veils of organic fibers positioned above the collecting surface, the veils of mineral fibers being generally colinear with the veils of organic fibers, the veils of organic fibers alternating with the veils of mineral fibers to integrate the organic material and the mineral fibers, and collecting the integrated organic material and mineral fibers on the collecting surface.
Patent DE-69518898-T2 (DE)
Inventor: ALIVES PORTA MIGUEL
IPC: B29C70/46
Filed: 1995-11-06
Granted: 2001-04-12
Abstract: The invention relates to a process and an arrangement for the three-dimensional forming of a fabric. The process comprises the steps of providing a countermould (56); preparing a complex sheet by superimposing a sheet of plastics, hot-melt material and a fabric; die-cutting the complex sheet; superimposing the die cut complex sheet (26) over the fabric (14); attachment of the die cut complex sheet (26) to the fabric (14) by pressing and heating until the fabric (14) is impregnated by melting of the hot-melt material; and application of the ensemble of the complex sheet (26) and fabric (14) to the countermould (56) by blowing pressurized air. The arrangement comprises a frame receiving the fabric to be formed and which is movable through various workstations wherein the process steps take place. <IMAGE>
Patent DE-69521060-T2 (DE)
Inventor: ERIKSSON TORE
IPC: D21H23/32
Filed: 1995-12-05
Granted: 2001-11-08
Abstract: Application apparatus for the coating of a travelling web (5), comprising a support roll (3) and a predosage roll (7'), said rolls forming a nip between themselves through which the web is brought to travel, further comprising an application device (21) by which sizing agent or coating agent (13) can be transferred onto the web, and means (19) for final evening of material applied onto the web, characterized in that the application device (21) is designed in such a manner that it transfers directly onto the travelling web (5) said material (13) in a certain excess before entering the nip where predosage is provided before the subsequent and final evening of applied material.
Patent DE-69523847-T2 (DE)
Inventor: ABE HIROSHI
IPC: G01M3/32
Filed: 1995-03-30
Granted: 2002-06-27
Abstract: A pinhole detector for accurately and speedily detecting pinholes in a sealed container. The detector comprises a pallet (1) which removably holds gas-filled containers (11) and which has an air inlet (13) closable to keep the pallet sealed; a gas leak detector (2) connected to the air inlet (13) in an examination position, communicating with the interior of the pallet (1) and adapted to generate an analog voltage corresponding to leakage per unit time if the same gas in the container is present; an A/D converter (3) adapted to convert this analog signal into a digital signal; and a first arithmetic unit (4) adapted to determine on the basis of this signal the gradient of a linear regression line representative of the relation between voltage and time, calculate a difference between this gradient and a maximum value of the gradient which has been inputted in advance of a linear regression line in the air the above-mentioned gas and output an abnormality signal when this difference is out of a permissible range. <IMAGE>
Patent DE-69620101-T2 (DE)
Inventor: CHAUQUET JACQUES
IPC: H02B1/20
Filed: 1996-11-13
Granted: 2002-08-29
Abstract: A bus bar panel system utilizes a quick acting and simplified fastening system for making connections. The bus bar is preferably pre-perforated along the edges, although holes may be drilled at the time of fastening. The fastening system uses a stud having threads on one end for receiving the usual washers and nut. On the other end, usually away from the installer, the stud is provided with flats which engage an open slot or yoke on a keeper clip. The clip has a gauge flange to engage the edge of the bar or clamp through which the stud extends. The transverse dimensions of the open slot are related to the flats and the length of the slot to the distance of the perforations from the edge of the bar. The clip also includes a spring section which grabs the end of the stud holding the clip in place so that the installer has both hands free to secure the nut and washers. The clip, while providing the requisite area and stiffness for a good electrical connection, occupies very little space axially of the stud to fit between bars of a common phase. A wide variety of connections may be made more easily with fewer parts less apt to be dropped in locations which would normally require partial disassembly of the panel system or housing. <IMAGE>
Patent DE-69621598-T2 (DE)
Inventor: LEE KUO-HSIUNG
IPC: C07D491/052
Filed: 1996-02-21
Granted: 2003-08-14
Abstract: Compounds, including compositions and methods of making and using these compounds for treating retroviral infections, are provided according to formula (G-1):    <IMAGE>  (G-1)  wherein M is O or NH; Z is O, NH or S; R240, and R250 are each H, C1-10 alkyl, C1-10 aryl, alkyl, amide, or CH2COOR260, where R260 is C1-10 alkyl or acyl; R200, R210, R220 and R230 are each H, halogen, hydroxyl, NH2, NH-alkyl, N-(alkyl)2, O-alkyl, O-acyl, COCF3, OCF3 or CH2COO NH-alkyl; or R200 and R210 form C5-C10 cyclo or heterocyclo optionally substituted with one or more of halogen, hydroxyl, NH2, NH-alkyl, N-(alkyl)2, O-acyl, O-alkyl, CO, CF3, OCF3 or CH2 COONH-alkyl; wherein C3 and C4 can be bound by a single or double bond; configurations at 3' or 4' can be (R) or (S); and R240 and R250 are either cis- beta  or cis alpha , or trans-3'- alpha  or trans-3'- beta  oriented. Stereoselectivity can be enhanced by preparing these compounds by catalytic asymmetric dihyroxylation.
Patent DE-69636609-T2 (DE)
Inventor: WEILANDT ANDERS
IPC: A61B17/32
Filed: 1996-01-15
Granted: 2007-08-16
Abstract: A biopsy apparatus comprising a biopsy instrument (20) and means (10) for holding and controlling the biopsy instrument during tissue extraction. The biopsy instrument includes a tube (3) having a finger-like projection at one end and a cannula (4) slidably disposed in the tube. After insertion of the biopsy instrument into a tissue, the tube is displaced on the cannula so that the projection passes through an aperture in the cannula to sever the tissue sample in the cannula bore from the tissue. The projection retains the severed sample in the cannula bore during withdrawal of the biopsy instrument from the tissue. A holding and control assembly (10) having a first and second spring is provided for moving the tube and cannula in a forward direction to penetrate the tissue and then substantially consecutively moving the tube in the forward direction to sever and retain the sample in the cannula bore.
Patent DE-69702526-T2 (DE)
Inventor: RUITER ANTONIUS
IPC: C21D9/56
Filed: 1997-04-09
Granted: 2001-03-08
Abstract: The vertical annealing furnace for the continuous bright annealing of a metal strip guided through the furnace comprises: a vertically disposed muffle having a strip entry side and a strip exit side, the muffle having the freedom to expand in a longitudinal direction, and the muffle being disposed such that the strip entry side is situated at a top side of the muffle and the strip exit side is situated at an underside of the muffle; heating structure for externally heating the muffle; bearing structure for fixedly supporting the underside of the muffle such that it is delimited downwards in the longitudinal direction; an expansion section being provided on the top side of the muffle for taking up thermal expansion in the longitudinal direction of generally the entire muffle; and vertically movable support structure for exerting an upwardly directed support force on the muffle, the vertically movable support structure being connected to an upper part of the muffle.
Patent DE-69717909-T2 (DE)
Inventor: DEBORD GUY
IPC: B08B3/08
Filed: 1997-05-16
Granted: 2003-11-13
Abstract: The cleaning method involves spraying the porous surface with an aqueous preparation containing bacteria, such as pseudomonas or moraxella, with an enzymic activity producing a hydrolysis of hydrocarbons by bio-surfactants or natural surfactants. After leaving the preparation to work for an appropriate time it is rinsed off and recovered by suction, together with any residues. The area to be cleaned can be pre-treated by spraying it with a liquid at a pressure of under 90 bars and a temperature below 60 deg C, recovering the liquid after a period of some 5-20 min. The pre-treatment liquid comprises a 1-2 per cent aqueous solution of a biosurfactant complex derived from bacteria with an associated biodegradable surfactant. The enzyme and biosurfactant solutions can be produced on the spot with reactors, and the surface to be treated can be pre-cleaned mechanically with brushes if it has accumulated surface deposits.
Patent DE-69726878-T2 (DE)
Inventor: FELDMANN MARC
IPC: C07K16/24
Filed: 1997-11-17
Granted: 2004-10-21
Abstract: Methods for treating and/or preventing a TNF-mediated disease in an individual are disclosed. Also disclosed are compositions comprising a TNF antagonist and an IL-12 antagonist. TNF-mediated diseases include rheumatoid arthritis, Crohn's disease, and acute and chronic immune diseases associated with transplantation.