baber/WOPTO huggingface dataset:
Patent MX-2022003572-A (MX)
Title: Compositions comprising a combination of an anti-pd-1 antibody and another antibody.
Inventor: SADINENI Vikram
IPC: A61K39/395
Filed: 2017-10-13
Abstract: This provides pharmaceutical compositions that comprise a combination of an anti-cancer agent which is an first antibody and a second antibody. In some embodiments, the first antibody is an anti-Programmed Death-1 (PD-1) antibody. In certain embodiments, the composition is a fixed dose formulation. In certain embodiments, the composition is administered as a flat-dose. The disclosure also provides a kit for treating a subject afflicted with a disease, the kit comprising a dosage of any composition disclosed herein and instructions for using the composition in any of the disclosed methods for treating a disease.
Patent MX-2022004598-A (MX)
Title: Immunogenic compounds for treatment of adrenal cancer.
Inventor: CHENE LAURENT
IPC: A61K35/17
Filed: 2020-10-16
Abstract: The present invention relates to antigen-based immunotherapy targeting interleukin 13 receptor alpha 2 (IL13RA2), BIRC5 and/or FOXM1 for treatment of adrenal cancers. In particular, the present invention provides the use of a (poly)peptide comprising an epitope of IL13RA2, BIRC5 and/or FOXM1 or a sequence variant thereof for treatment of an adrenal cancer. Moreover, the present invention also provides combinations of the (poly)peptide comprising an epitope of IL13RA2, BIRC5 and/or FOXM1 or a sequence variant thereof with (poly)peptides comprising other epitopes or sequence variants thereof for treatment of adrenal cancers.
Patent MX-2022004648-A (MX)
Title: Pigment with enhanced durability and plastic materials made therewith.
Inventor: EL-SHOUBARY MODASSER
IPC: C09C1/36
Filed: 2020-10-15
Abstract: The invention provides a method for enhancing the durability of a titanium dioxide material, the method including mixing citric acid and an alumina source with an aqueous slurry of titanium dioxide particles and water to form a mixture, the mixture having an acidic pH; and raising the pH of the mixture to a pH of no more than about 7.5 to form alumina-coated titanium dioxide particles. The invention also provides a pigmented plastic article including alumina-coated titanium dioxide particles prepared according to the invention dispersed in a polymer material.
Patent MX-2022005828-A (MX)
Title: Composition and method for treating hematologic cancers.
Inventor: WACHTER ERIC A
IPC: A61K51/10
Filed: 2019-11-19
Abstract: A method of treating a mammalian subject having hematologic, non-tumorous cancer cells is disclosed. The method comprises the steps of: (A) administering to such a mammalian subject a therapeutically effective amount of a halogenated xanthene, a pharmaceutically acceptable salt or a C2-C4 alkyl ester thereof as a first cancer cytotoxic agent dissolved or dispersed in a pharmaceutically acceptable aqueous medium. The mammalian subject is maintained for a period of time sufficient to induce death of hematologic, non-tumorous cancer cells. A contemplated administration is typically repeated, A contemplated treatment method can also be carried out in conjunction with administration to said mammalian subject of a second therapeutically effective amount of a second, differently-acting cancer cytotoxic agent dissolved or dispersed in a pharmaceutically acceptable medium, The second cancer cytotoxic agent can be a small molecule or an intact antibody or paratope-containing portion thereof.
Patent MX-2022006438-A (MX)
Title: Processes for producing fermentation products.
Inventor: KURAKATA YUMA
IPC: C12P7/06
Filed: 2020-12-16
Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable xylanase that is resistance to inhibition by metal ions in the liquefying starch-containing material is present and/or added during liquefaction.
Patent MX-2022006909-A (MX)
Title: Methods for culturing filamentous fungi in fermentation media.
Inventor: MACUR RICHARD EUGENE
IPC: C12M1/00
Filed: 2020-12-10
Abstract: Methods for culturing filamentous fungi, in which the filamentous fungi are grown in a colloid of air and a fermentation medium, are provided. The methods result in more rapid and prolific growth of the filamentous fungus than has been achieved by previous methods. Biomats produced by the methods and air-medium colloids for use in the methods are also provided.
Patent MX-2022007111-A (MX)
Title: Multi-benefit personal care compositions and methods for the same.
Inventor: BOYD THOMAS
IPC: A61K8/92
Filed: 2020-11-12
Abstract: Personal care compositions and methods for increasing the amount of antimicrobial peptides produced by skin, reducing inflammation of skin, reducing irritation of skin, reducing reactive oxygen species in skin, or any combination thereof are disclosed. The personal care composition may include a carrier and at least two plant oils. The at least two plant oils may be present in an effective amount to increase the amount of antimicrobial peptides produced by skin, reduce inflammation of skin, reduce irritation of skin, reduce reactive oxygen species in skin, or any combination thereof.
Patent MX-2022009830-A (MX)
Title: Bcma-directed chimeric antigen receptor t cell compositions and methods and uses thereof.
Inventor: BURGESS MICHAEL
IPC: A61K35/17
Filed: 2021-02-11
Abstract: Provided in some aspects are compositions of cells for treating subjects with disease and conditions such as multiple myeloma (MM), and related methods, compositions, uses and articles of manufacture. In some embodiments, the disease or condition is a relapsed or refractory multiple myeloma (r/r MM). The cells generally express recombinant receptors such as chimeric antigen receptors (CARs) for targeting an antigen, such as BCMA, on cells of the myeloma.
Patent MX-2022010151-A (MX)
Title: Antimicrobial and microstatic sensor systems.
Inventor: MCCANLESS JONATHAN D
IPC: A61B5/00
Filed: 2021-02-19
Abstract: A sensor control device and methods of making them are described. The sensor control device includes an electronics housing and a plug assembly. The electronics housing includes an upper shell matable to a lower mount having a skin-facing surface. The plug assembly is coupled to the electronics housing and includes a sensor module that has a sensor and a sharp module having a sharp. The plug assembly includes a base having a skin-facing surface and a plug portion comprising a lumen therethrough. At least a portion of a surface of the electronics housing or the plug assembly comprises an antimicrobial agent. The antimicrobial agent may be a metal and/or a metal oxide.
Patent MX-2022010556-A (MX)
Title: Use of peptidylglycine alpha-amidating monooxygenase (pam) for therapeutic purpose.
Inventor: BERGMANN ANDREAS
IPC: A61K38/43
Filed: 2021-02-26
Abstract: The present invention is directed to peptidylglycine alpha-amidating monooxygenase (PAM) for use as a medicament and the treatment of a subject, wherein said treatment comprises: reducing the potential or risk for a disease or disorder, and/ or reducing the occurrence of a disease or disorder, and/ or reducing the severity of a disease or disorder.
Patent MX-2022012279-A (MX)
Title: Aav capsids variants and uses thereof.
Inventor: LUO LI
IPC: C07K14/005
Filed: 2021-03-30
Abstract: Aspects of the disclosure relate to compositions and methods for delivering a transgene (e.g., a transgene encoding one or more gene products) to a target cell. The disclosure is based, in part, on adeno-associated virus (AAV) capsid protein variants characterized by tropisms for certain cell types (e.g., neurons, muscle cells, bone cells, heart cells, etc.). In some embodiments, recombinant A A Vs (rAAVs) comprising the capsid protein variants (e.g., AAVv66, SEQ ID NO: 1) are more efficiently packaged than rAAVs having certain wild-type AAV capsid proteins. Methods of delivering an rAAV comprising the AAV capsid protein variants are also described by the disclosure.
Patent MX-PA00011127-A (MX)
Title: Concrete comprising organic fibres dispersed in a cement matrix, concrete cement matrix and premixes.
Inventor: CHEYREZY MARCEL
IPC: C04B40/02
Filed: 1999-05-12
Abstract: The invention concerns a concrete comprising organic fibres dispersed in a cement matrix. By combining a cement matrix with predetermined characteristics and organic fibres likewise with predetermined characteristics, in particular the size of the particles, the length and diameter of the fibres, by a synergistic effect between the matrix and the organic fibres, the behaviour of the concrete is improved both with respect to the occurrence of minute cracks and the propagation of large cracks. The figure is a graph resulting from four-point bend tests for metal fibre concrete mixes and organic fibre concrete mixes.
Patent MX-PA01001740-A (MX)
Title: Self gapping socket weld fittings.
Inventor: ALBERT A MCKAY
IPC: F16L13/04
Filed: 2001-02-16
Abstract: The present invention provides a positive gapping device for socket welded fittings. The positive gapping device comprises a socket fitting having a recessed area on at least one end for receiving a pipe section that is engageable with the recessed area of the socket fitting. It further includes a gapping means disposed on one of a surface of the recessed area of the socket fitting facing an end of such pipe section and an end of such pipe section for engagement with such socket fitting. The gapping means providing a space between the socket fitting and such pipe section for reducing residual stresses that result from a welding operation.
Patent MX-PA01002011-A (MX)
Title: Fluid filtration and dispensing system.
Inventor: MALCOM D POIRIER
IPC: C02F1/00
Filed: 2001-02-23
Abstract: The present invention provides a fluid dispenser. The flow of either filter or unfiltered fluid may be selected by positioning an actuator that also contains the filter. Selection is accomplished by positioning the actuator within two planes that are not coincident, or by positioning the actuator along a single axis.
Patent MX-PA01006742-A (MX)
Title: 3-heteroarylidenyl-2-indolinone compounds for modulating protein kinase activity and for use in cancer chemotherapy.
Inventor: TANG PENG CHO
IPC: A61K31/506
Filed: 1999-12-30
Abstract: The present invention relates to 3-heteroarylidenyl-2-indolinone compounds that modulate the enzymatic activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer. Furthermore, these compounds are expected to enhance the efficacy of other chemotherapeutic agents, in particular, fluorinated pyrimidines, in the treatment of cancer.
Patent MX-PA01006879-A (MX)
Title: Method of determining the efficiency of an absorbent article having two absorbent layers that each contain a superabsorbent.
Inventor: EARLE HARRY SHERROD
IPC: A61F13/15
Filed: 2001-07-05
Abstract: A method is disclosed for determining the efficiency of an absorbent article having first and second absorbent layers. The method comprises the steps of selecting a density for the first absorbent layer and for the second absorbent layer. A basis weight for each of the first and second absorbent layers is selected which is at least about 100 grams per square meter. A desired percentage of a superabsorbent to be present in each of the first and second absorbent layers is also selected. The percentage of a superabsorbent present in the first absorbent layer is greater than the percentage of a superabsorbent present in the second absorbent layer. The selected densities and percentages of a superabsorbent are then inserted into the following formula:In this formula:% SAM1 is the percentage of a superabsorbent present in the first absorbent layer;% SAM2 is the percentage of a superabsorbent present in the second absorbent layer;d1 is the density of the first absorbent layer expressed in gsm;d2 is the density of the second absorbent layer expressed in gsm; andV is the desired value to form an efficiency absorbent article.The selected densities and the selected percentages of a superabsorbent in the first and second absorbent layers are then adjusted to obtain a value "V" which is at least equal to 2.
Patent MX-PA01011944-A (MX)
Title: Processes for drying and curing primer coating compositions.
Inventor: EMCH DONALDSON J
IPC: F26B3/28
Filed: 2000-05-15
Abstract: Processes for drying primer coating compositions applied to a surface of a substrate are provided in which the primer coating composition, if a liquid or powder slurry, is exposed to low velocity air having a temperature ranging from about 10 °C to about 50 °C for a period of at least about 30 seconds to volatilize at least a portion of volatile material from the liquid primer coating composition. Next, infrared radiation and low velocity warm air are applied simultaneously to the primer coating composition (liquid, powder slurry or powder) for a period of at least about 1 minute during which the temperature of the substrate is increased at a rate ranging from about 0.2 °C per second to about 2 °C per second to achieve a peak substrate temperature of the substrate ranging from about 30 °C to about 120 °C. Infrared radiation and hot air are applied simultaneously to the primer composition for a period of at least about 2 minutes during which the temperature of the substrate is increased at a rate ranging from about 0.1 °C per second to about 1 °C per second to achieve a peak temperature of the substrate ranging from about 40 °C to about 155 °C, such that a dried primer coating is formed upon the surface of the substrate.
Patent MX-PA02002939-A (MX)
Title: Long life traveling spark ignitor and associated firing circuitry.
Inventor: SHCEMMANN GUNTER
IPC: F02P9/00
Filed: 2000-06-16
Abstract: An ignitor and associated electronics for igniting a combustible mixture in a cylinder of an internal combustion engine are described. The ignitor includes at least two spaced-apart electrodes that define a discharge gap. The space between the electrodes is substantially filled with a dielectric material. The dielectric material is spaced-apart from at least one of the electrodes to provide an air gap over which an initial voltage breakdown between the electrodes will occur. The air gap serves to vary the location of the initial breakdown and as a barrier to a short circuit between the electrodes due to carbon and/or metal deposit buildup on the dielectric material. The associated electronics provide a first potential between the electrodes that generates a plasma between the electrodes. Then the volume of the plasma is increased by the application of a second potential that creates a current through the plasma. The plasma, as well as the current passing through, is swept outward due to the interaction of Lorentz and thermal expansion forces with the plasma. Also described are relative orientations of the electrodes that lead to greater plasma formation.
Patent MX-PA02003670-A (MX)
Title: Salts and bases of 17-(cyclopropylmethyl)-4,5 alpha-epoxy-6-methylenemorphinan-3,14 diol for optimizing dopamine homeostasis during administration of opioid analgesics.
Inventor: SIMON DAVID LEW
IPC: A61K31/167
Filed: 2001-07-12
Abstract: A kappa opioid blocking agent is used for optimizing dopamine homeostasis during administration of opioid analgesics, for preventing mortal respiratory depression due to drug overdose, and for dissuading a human or animal from self-administering excessive amounts the opioid analgesic.
Patent MX-PA02003765-A (MX)
Title: Actuating fluid delivery system for a fuel injector.
Inventor: ZIELKE MARTIN R
IPC: F02M55/00
Filed: 2000-10-25
Abstract: A fluid delivery system (10) for delivering a supply of a fluid from a fluid source to a fuel injector (200) includes a rail (12) for conveying a fluid and being positionable proximate the fuel injector (200). The rail (12) has a fluid passageway (28) defined therein, the fluid passageway (28) being in fluid communication with the source of fluid. A connector (14) is in fluid communication with both the rail (12) and with the fuel injector (200) for fluidly connecting the rail (12) to the fuel injector (200). The connector (14) is universally moveable in three axes for accommodating static tolerances existing between the rail (12) and the fuel injector (200) and for accommodating dynamic relative motion between the rail (12) and the fuel injector (200) such that stresses imposed on the fuel injector (200) resulting from being attached to the rail (12) are substantially eliminated.
Patent MX-PA02005053-A (MX)
Title: Composite insulator with an optical fiber guided between a metal end-fitting and the support rod.
Inventor: ERIC MOAL
IPC: H01B17/32
Filed: 2002-05-20
Abstract: A composite electrical insulator comprises a support rod generally of a composite material, two metal end-fittings each forming a socket in which a corresponding end of the support rod is inserted, at least one optical fiber placed on the outer periphery of the support rod, and an insulating outer coating surrounding the support rod and covering the optical fiber which has at least one end guided to the outside of the insulator through an end-fitting via a groove formed in the inside surface of the socket of the end-fitting, said groove opening to the outer periphery of the support rod, and via a duct extending said groove and opening to the outside of the end-fitting.
Patent MX-PA02005416-A (MX)
Title: Bicycle moved by front and rear drive method of pedal.
Inventor: HEO HYUN KANG
IPC: B62M1/36
Filed: 2000-08-31
Abstract: This invention relates to a bicycle with a forward and backward pedaling system which drives a bicycle forward in either a forward or a backward pedaling. This invention relates to a bicycle moved by front and rear drive method of pedal which comprises a backward driving sprocket (6) which is installed on a driving shaft (5) for a load driving in forward direction but a no load driving in backward direction; a forward driving sprocket (7) which is installed on the driving shaft (5) for a load driving in forward direction but a no load driving in backward direction, and connects an upward induction sprocket (12) which is installed for a no load driving on the top of a support part (10) that is placed along the top of the backward driving sprocket (6) and rearward induction sprocket (16) which is connected to a rearward driving shaft (15) for a no load driving and is placed at the bottom of a support part (10) that is placed along the lower rear direction of the upward induction sprocket (12) with a driving chain (8); and an auxiliary induction sprocket (17) which is installed on the rearward driving shaft (15) for a no load driving, and the forward driving sprocket (7) and the auxiliary induction sprocket (17) are connected by an auxiliary chain. The bicycle in this invention can move forward in backward pedaling as well as in forward pedaling. Therefore, one can ride on a bicycle for an extended period while changing posture, can climb up a hill with reduced power consumption by pedaling in a backward direction. This invention is simply applicable to all bicycles, practical and useful.
Patent MX-PA02005568-A (MX)
Title: Pigment preparations that are improved with regard to safety regulations.
Inventor: KLAUS SAITMACHER
IPC: C09B67/20
Filed: 2000-11-16
Abstract: The invention relates to a pigment preparation containing an organic pigment and 0.2 to 20 wt. % of an ammonium polyphosphate or an organophosphorous compound in relation to the total weight of the pigment preparation.
Patent MX-PA02006288-A (MX)
Title: System and method for determining and controlling the impact of text.
Inventor: FOGEL DAVID B
IPC: G06F17/27
Filed: 2000-12-20
Abstract: A computer program that indicates lexical impact of various words in a text and provides various statistics relating to lexical impact of the text. Also, a ranked thesaurus for listing alternative words (e.g., synonyms, antonyms, related), along with an indication of their relative lexical impact (item 141). The thesaurus may alternatively rank words according to ranking system.
Patent MX-PA02006938-A (MX)
Title: Improved pediatric formula and methods for providing nutrition and improving tolerance.
Inventor: BORSCHEL MARLENE W
IPC: A23L33/00
Filed: 2001-01-16
Abstract: The present invention provides an improved pediatric formula and methods for providing nutrition to and enhancing tolerance in pediatric patients. The formula may be provided in powder, concentrate or ready to feed forms. The pediatric formula comprises, based on a 100 kcal basis, about 8 to about 16 grams carbohydrate (preferably about 9.4 to about 12.3 grams), about 3 to about 6 grams lipid (preferably about 4.7 to about 5.6 grams), about 1.8 to about 3.3 grams protein (preferably about 2.4 to about 3.3 grams), and a tolerance improver comprising about 37 to about 370 milligrams (preferably about 74 to about 222 milligrams, more preferably about 111 to about 148 milligrams) xanthan gum. The formula may also be provided in a powder, which comprises, based on 100 grams of powder, about 30 to about 90 grams carbohydrate (preferably about 48 to about 59 ), about 15 to about 30 grams lipid (preferably 22 to about 28 grams), about 8 to about 17 grams protein (preferably about 11 to about 17), and about 188 to about 1880 milligrams (preferably about 375 to about 1125, more preferably about 375 to about 1125 milligrams) xanthan gum. The formula preferably further comprises vitamins and minerals and may further comprise a stabilizer. The methods comprise administering to a pediatric patient an effective amount of a pediatric formula according to the invention, as described above.
Patent MX-PA02012145-A (MX)
Title: Pipe joint.
Inventor: NAGASAKU SHIGEO
IPC: F16L15/06
Filed: 2001-06-08
Abstract: A pipe joint, comprising a shape having a stub side clearance (C) of 0.5-1.0 mm, a stub side thread angle (thgr;) of 15-60, the top and bottom faces of a thread positioned parallel with an axis, and a radius (R) at a male thread stub side corner of 1.0-1.25 mm, wherein a pin part having a tapered male screw formed in the end part outer peripheral surface of a tube is threaded with a box part having a tapered female screw threaded with the tapered male screw formed in the end part inner peripheral surface of the tube or a short tube, the taper of the incomplete thread part of the pin part being desirable to be 0.96-0.90 times the reference taper of the complete thread part.
Patent MX-PA02012664-A (MX)
Title: Peptides for the preparation of vaccines against bordetella pertussis.
Inventor: MOOI FREDERIK ROBERT
IPC: A61K39/002
Filed: 2001-06-29
Abstract: The present invention discloses polypeptides for use in vaccines against pertussis and parapertussis. The polypeptides of the invention are derived from the Bordetella pertussis pertactin. Preferably, the polypeptides of the invention comprise sequences from region 1 of pertactin, in particular they comprise one or more GGFGP or GGAVP repeats. Alternatively the polypeptides of the invention have a pertactin sequence from which part or all of region 1 or region 2 is deleted. The polypeptides of the invention are incorporated in compositions that are useful as vaccines for human and veterinary purposes. The invention further discloses antibodies against the pertactin-derived polypeptides of the invention.
Patent MX-PA03002722-A (MX)
Title: Fine denier spunbond process and products thereof.
Inventor: FERENCZ RICHARD LEON
IPC: B32B27/12
Filed: 2001-10-05
Abstract: A nonwoven fabric comprising one or more fine-denier spunbond layers and one or more barrier layers. each spunbond layer comprises continous filaments having a denier between 0.7 and 1.2, which filaments are chosen from polyesters, polyolefins and blends thereof.