Patent SG-11201807313P-A (SG)
Title: Assay for determining the total carbonylation level on a polypeptide
Inventor: MAH ANNA
IPC: G01N33/68
Filed: 2017-05-18
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization MD HEIM 1111111111111111111111111111111111111111011111111111111111111111011111 International Bureau (10) International Publication Number (43) International Publication Date ......0\"\" WO 2017/201312 Al 23 November 2017 (23.11.2017) WIPO I PCT (51) International Patent Classification: G01N 33/50 (2006.01) G01N 33/68 (2006.01) Declarations under Rule 4.17: G01N 33/533 (2006.01) — as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(H)) (21) International Application Number: PCT/US2017/033371 — as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) (22) International Filing Date: — of inventorship (Rule 4.17(iv)) 18 May 2017 (18.05.2017) Published: (25) Filing Language: English — with international search report (Art. 21(3)) (26) Publication Language: English (30) Priority Data: 62/338,605 19 May 2016 (19.05.2016) US (71) Applicants: GENENTECH, INC. [US/US]; 1 DNA Way, South San Francisco, California 94080 (US). UNIVERSI- TY OF KANSAS [US/US]; 245 Strong Hall, 1450 Jayhawk Boulevard, Lawrence, Kansas 66045 (US). _ (72) Inventors: MAH, Anna; c/o Genentech, Inc., 1 DNA Way, South San Francisco, California 94080 (US). YANG, Yi; c/ o Genentech, Inc., 1 DNA Way, South San Francisco, Cali- - fornia 94080 (US). GAO, Di; 15824 Glacier Ct., North Po- tomac, Maryland 20878 (US). GENNARO, Lynn A.; c/o = Genentech, Inc., 1 DNA Way, South San Francisco, Cal- = ifornia 94080 (US). SCHOENEICH, Christian; c/o Uni- - = versity of Kansas, 245 Strong Hall, 1450 Jayhawk Boule- vard, Lawrence, Kansas 66045 (US). (74) Agent: BERENDT, Frank JN et al.; c/o Genentech, Inc., 1 DNA Way, Mail Stop 49, South San Francisco, California 94080 (US). Designated States (unless otherwise indicated, for every = (81) = kind of national protection available): AE, AG, AL, AM, = AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, = = CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, = DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, = HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, = = PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, = — SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, = TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every = kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, — 1-1 N UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, 1-1 MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, M TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, 1-1 0 N KM, ML, MR, NE, SN, TD, TG). IN 1-1 (54) 0 Title: ASSAY FOR DETERMINING THE TOTAL CARBONYLATION LEVEL ON A POLYPEPTIDE N (57) : The description relates to a method and kits for determining the total carbonylation level on a polypeptide.