baber/WOPTO huggingface dataset:
Patent DK-1962850-T3 (DK)
Inventor: PISANO CLAUDIO
IPC: A61K31/4745
Filed: 2006-12-13
Granted: 2012-06-18
Abstract: A subclass of camptothecin derivatives is disclosed to be useful for the preparation of a medicament for the treatment of drug-resistant tumors and/or for the administration to patients who show polymorphisms in the gene coding for DNA topoisomerase I.
Patent DK-1878415-T3 (DK)
Inventor: AMANN TOBIAS
IPC: A61G5/10
Filed: 2007-05-11
Granted: 2009-06-22
Abstract: The device has a driving motor (5), two drive wheels (1,2), a steering device and fastening parts for docking at a wheelchair. The two drive wheels are positioned commuting around a floating axle (180) and are interconnected by a differential. The floating axle runs perpendicularly to the axis of rotation of the two drive wheels in a plane. The drive wheels are rigidly connected with the driving motor.
Patent DK-1975183-T3 (DK)
Inventor: GOLETZ STEFFEN
IPC: A61K47/48
Filed: 2003-12-01
Granted: 2012-07-30
Abstract: Recognition molecules (RM), especially antibodies (A) that bind specifically to the Core-1 (C1) antigen, comprising defined amino acids sequences (1-6) given in the specification and below, are new. Recognition molecules (RM), especially antibodies (A) that bind specifically to the Core-1 (C1) antigen, comprising defined amino acids sequences (1-6): (a) AsnTyrTrpLeuGly (1); (b) AspIleTyrPro(Gly) 3TyrThrAsnTyrAsnGluLysPheLysGly (2); (c) AspIleTyrPro(Gly) 2SerTyrThrAsnTyrAsnGluLysPheLysGly (3); (d) TyrAspAlaAlaGlyProTrpPheAlaTyr (4); (e) TyrAspAlaAlaGlyProGlyPheAlaTyr (5); or (f) TyrAspAsnHisTyrPheAspTyr (6). Independent claims are also included for: (1) construct (B) consisting of (A) fused, chemically coupled or non-covalently associated with additional sequences and/or structures; (2) isolated nucleic acid (NA) containing sequences that encode at least one (A) or (B); (3) expression cassette or vector (X) comprising NA and functionally linked promoter; (4) virus or host cell that contains at least one (X); (5) organism that contains at least one host cell of (4); (6) method for preparing (A); and (7) kit containing (A) and/or (B). ACTIVITY : Cytostatic. A multibody (104; sequence of about 200 amino acids reproduced) was coupled to a chelating group then loaded with yttrium99. It was injected (dose 100 MicroCi) into the tail vein of a mouse, subcutaneously implanted with ZA-75-1 (Core-1 positive) tumor cells. A second dose was given after 3 weeks and this treatment produced a significant reduction in tumor growth (no figures given). MECHANISM OF ACTION : Neutralization of Core-1 antigen; Vaccine.
Patent DK-2107103-T3 (DK)
Inventor: KURODA TAICHI
IPC: C10L1/14
Filed: 2008-02-21
Granted: 2012-07-16
Abstract: A fuel additive contains ferrocene and/or ferrocene derivative(s), and lecithin. A fuel additive contains 80 to 99 mass % of ferrocene and/or ferrocene derivative(s), and 1 to 20 mass % of lecithin, and being in the solid state. A fuel additive contains 78 to 99 mass % of ferrocene and/or ferrocene derivative(s), 0.9 to 20 mass % of lecithin and 0.1 to 2 mass % of water, and being in the particle state. A fuel additive containins 2 to 5 mass % of ferrocene and/or ferrocene derivative(s), 5 to 50 mass % of lecithin and mineral oil, and being in the liquid state, wherein the ferrocene and/or ferrocene derivative(s), and the lecithin are dissolved in the mineral oil. The above-mentioned fuel additive is used by being added into a fuel so as to make the concentration of the ferrocene and/or ferrocene derivative(s) and the lecithin in ranges of 1 to 50 ppm, and 0.01 to 500 ppm, respectively.
Patent DK-2231662-T3 (DK)
Inventor: PRICE STEPHEN
IPC: A61P35/00
Filed: 2008-12-18
Granted: 2011-08-29
Abstract: The invention relates to imidazopyridines of formula I with anti-cancer and/or anti-inflammatory activity and more specifically to imidazopyridines which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.(Formula I)
Patent DK-2110344-T3 (DK)
Inventor: REIST WALTER
IPC: B65G15/28
Filed: 2007-01-08
Granted: 2012-11-05
Abstract: The device has a drive wheel for pushing thrust units (2) along a conveyor path, where the wheel engages with a roller (3) and a spacer body (4) of each thrust unit. Each of the spacer bodies arranges the thrust units at a distance from each other, where the thrust units extend in a conveying direction from one end to another end. Each thrust unit is movably supported in an area of the former end, and is supported in an area of the latter end on an adjacent thrust unit. The thrust units are loaded with respect to each other with a compressive load but not with a tensile load.
Patent DK-2384318-T3 (DK)
Inventor: CHARMOT DOMINIQUE
IPC: C07F9/62
Filed: 2009-12-30
Granted: 2018-02-19
Abstract: The present disclosure is directed to compounds of the structure (X): CoreL-NHE)n  (X) wherein: n is 2 or 3; NHE has the structure wherein: R1 is H or —SO2—NR7R8—; R2 is selected from H, —NR7(CO)R8, —SO2—NR7R8— and —NR7R8; R3 is hydrogen; R7 is hydrogen; R8 is a bond linking to L; L is a polyalkylene glycol linker; and Core has the following structure: wherein: X is selected from the group consisting of a bond, —O—, —NH—, NHC(═O)—, —NHC(═O)NH— and —NHSO2—; and Y is selected from the group consisting of a bond, optionally substituted C1-6 alkylene, optionally substituted benzene, pyridinyl, a polyethylene glycol linker and —(CH2)1-6O(CH2)1-6—, and methods of using such compounds for the treatment of irritable bowel syndrome, chronic kidney disease and end-stage renal disease.
Patent DK-2180472-T3 (DK)
Inventor: HAYASHI KAZUHIRO
IPC: G11B7/24047
Filed: 2003-09-04
Granted: 2012-01-16
Abstract: A disc-shaped optical data recording medium has a signal recording layer for reading and/or writing data using light, and a 10 ¼m to 200 ¼m thick transparent protective layer disposed over the signal recording layer. The optical data recording medium includes a protrusion projecting from the surface of the transparent protective layer on the light-incidence surface side to which light is emitted to the signal recording layer. The protrusion is disposed in an area between a center hole and a clamping area (CA) where the optical data recording medium is held when reading and/or writing data in the signal recording layer.
Patent DK-2360258-T3 (DK)
Title: Aprotininpolypeptider to transport a compound of blood-brain-barrier
Inventor: BELIVEAU RICHARD
IPC: C12N15/15
Filed: 2005-07-21
Granted: 2015-01-12
Abstract: The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides derived from aprotinin and from aprotinin analogs as well as conjugates and pharmaceutical compositions comprising these polypeptides or conjugates. The present invention also relates to the use of these polypeptide for transporting a compound or drug across the blood-brain barrier of a mammal and in the treatment and diagnosis of neurological diseases.
Patent DK-2612623-T3 (DK)
Inventor: SHIBAYA MIAKI
IPC: A61F5/01
Filed: 2011-09-01
Granted: 2018-03-19
Abstract: [Problem] To provide an impact-absorbing pad satisfying all of the requirements for impact-absorbing pads that are used for hip protectors: the ability to absorb impact to prevent femoral neck fractures; wearing comfort, breathability and thinness that does not detract from the wearer's external appearance when used all day; and surface softness that does not cause discomfort when the pad is being put on or taken off; as well as clothing furnished with same and a method for preventing femoral fractures. [Solution] Femoral fractures are prevented by providing an impact-deflecting part (12), configured of a through hole or concavity with the length of the largest portion being 80 mm or less and the area being 600 mm2 to 5000 mm2 inclusive, on an impact-absorbing main pad body (11), and disposing the main pad body (11) so that the impact-deflecting part (12) coordinates with the greater trochanter of the femur (1).
Patent DK-2768859-T3 (DK)
Inventor: BÜLTMANN ANDREAS
IPC: C07K16/24
Filed: 2012-10-19
Granted: 2018-06-06
Abstract: The present invention provides antagonists of IL17C for use in the treatment of an inflammatory disorder.
Patent DK-2750683-T3 (DK)
Inventor: MOREIN BROR
IPC: A61K36/00
Filed: 2012-10-01
Granted: 2018-07-02
Abstract: The present invention regards nanoparticles comprising a sterol and a component derived from  Quillaja saponaria Molina  selected from  quillaja  acid and  quillaja  saponin, which nanoparticles do not comprise a phospholipid. It also relates to a composition comprising the nanoparticles, and the use thereof as adjuvant, especially in vaccines, as carriers for amphipathic or hydrophobic molecules and as agents for treatment of cancer. Further, it regards a method for producing the phospholipid-free nanoparticles, a method for the treatment of cancer and a method for assessing the applicability of the cancer treating method.
Patent DK-2674738-T3 (DK)
Inventor: LOWELL MARK EDMUND
IPC: G02B6/44
Filed: 2013-02-07
Granted: 2018-07-02
Abstract: Strain sensor, including an elongated protective encasing (5) surrounding an inner space, and an optical fiber (3) extending through the encasing (5), the fiber (3) at least including a fiber core (3a) and a fiber cladding (3b), wherein a cured filler material fills (4) at least part of a space between the fiber (3) and the protective encasing (5), the cured filler material (4) being configured for allowing strain coupling between the protective encasing (5) and the fiber (3), wherein an outer diameter of the fiber (3) is at least about 250 mum, and wherein the cured filler material (4) is one or more of: a flexible material, a resilient material, and a material having a shore A hardness that is lower than about 50. The invention also provides a method and system for manufacturing a strain sensor.
Patent DK-0380068-T3 (DK)
Inventor: ZERLER BRADLEY DR
IPC: C12N15/13
Filed: 1990-01-24
Granted: 1992-11-02
Abstract: The present invention relates to an expression system for producing chimeric antibodies. The expression system includes vectors that contains the entire human genomic constant region of a immunoglobulin heavy and/or light chain and is adaptable for insertion, without mutagenesis, of a nonhuman antibody variable region. The resulting expression vector incyludes the entire human genomic constant region and the entire nonhuman variable region lacking tissue specific promoter and/or enhancer regions normally associated with genomic DNA. Chimeric monoclonal antibodies to interleukin-2 receptor and tumor neucrosis factor are examples of chimeric monoclonal antibodies that can be produced by this method.
Patent DK-0401839-T3 (DK)
Inventor: TURUNEN AIMO
IPC: H01P1/205
Filed: 1990-06-07
Granted: 1997-02-10
Abstract: A dielectric filter is formed from a block of ceramic material with holes extending from a top surface toward a bottom surface. At least the bottom, both ends and one side surface are coated with conductive material. Also, the interior surfaces of the holes are coated with conductive material to form transmission line resonators. The uncoated side surface has an electrode pattern which allows coupling to the filter and between resonators of the filter. The elevation of the electrodes on the side surface between the top and bottom determines whether the coupling is capacitive, mixed inductive and capacitive, or inductive. <MATH>
Patent DK-0433590-T3 (DK)
Inventor: HERTING HEINRICH
IPC: A21B5/02
Filed: 1990-10-10
Granted: 1994-10-17
Abstract: The method and device allow waffles to be produced, such as individual waffles or the like, whose relatively thick layer of main dough bears an extremely thin, pattern-forming layer of dough produced by spraying onto a hot baking surface of the baking mould. The extremely thin layer of patterned dough is firstly sprayed onto the hot baking surface and the relatively thick, poured-on layer of main dough is then immediately joined to the layer of patterned dough. 
<??>The method and device allow rapid working and waffles with precise images. 
<IMAGE>
Patent DK-0443193-T3 (DK)
Inventor: MEINIG MANFRED
IPC: F16L23/00
Filed: 1990-12-22
Granted: 1994-03-07
Abstract: A butt connection between two air duct sections made of sheet metal has two flange frames fastened to opposed ends of two duct sections. Each flange frame is L-shaped in radial section, having an outer radially extending flange leg and an inner flange leg in a duct section, each flange frame comprising a hollow into which a leg of an L-shaped intermediate connection is fitted. Each flange frame is connected to the other flange frame, as by bolts, etc. The butt connection is equally applicable to duct sections which are of round, flattened oval, and rectangular cross sections, with the same flange frame shapes and essentially the same intermediate connector being usable.
Patent DK-0377542-T3 (DK)
Inventor: DURAND LUCIEN
IPC: A22B5/20
Filed: 1990-01-03
Granted: 1992-11-30
Abstract: Apparatus for cutting up carcasses in an abattoir, and in particular for cleaving them in two, comprises: a support beam securely mounted on a cleaving carriage via a pivot mount enabling the beam to pivot angularly about a pivot axis extending parallel to the cleaving direction; and adjustment means interposed between the cleaving carriage and the support beam to adjust the angular position of the beam about its pivot, and also to lock it in position. The apparatus is suitable for cutting up or cleaving in two the carcasses of slaughtered animals.
Patent DK-0437248-T3 (DK)
Inventor: IWATSCHENKO PETER
IPC: A61M25/00
Filed: 1991-01-08
Granted: 1994-08-08
Abstract: A catheter for introducing into a human body cavity has a flexible tube (10) which is provided at its distal end with an attachment (12) made of a substance which can be dissolved by body fluid. In order to guarantee a simple introduction of the catheter into the body cavity and a reliable positioning of the catheter end in the body cavity, the attachment (12) tapers conically in the distal direction R and projects beyond the end face (32) of the tube (10). <IMAGE>
Patent DK-0450501-T3 (DK)
Inventor: NEUMEISTER WALTER
IPC: F15B15/24
Filed: 1991-03-28
Granted: 1993-11-08
Abstract: To limit the extension of its displaceable parts, in particular the telescopic tubes (14, 15) and the piston (16), the actuator has conventional stop rings (23, 28) of round spring steel. Intermediate stop rings (35) lying between them in the stop position are provided in order to reduce the radial forces. <IMAGE>
Patent DK-0491298-T3 (DK)
Inventor: MERKENICH KARL DR
IPC: A23C19/082
Filed: 1991-12-13
Granted: 1994-09-26
Abstract: A novel type of processed cheese preparation is described, composed of cheese, fat, emulsifying salts, water and conventional additives such as emulsifiers, binders, thickeners, curd cheese, milk protein and flavourings in the conventional amounts, trisodium citrate and/or sodium phosphate being used as the emulsifying salts in a quantity of 1.5 - 3% and the mixture containing a modified starch having high amylopectin and low amylose content and/or highly esterified pectin in an amount of 0.25 - 2%.
Patent DK-0461958-T3 (DK)
Inventor: RAIZON BERNARD
IPC: A61P25/24
Filed: 1991-06-05
Granted: 1995-02-20
Abstract: A compound which is a 2-aminoalkyl-5-arylalkyl-1,3-dioxane of general formula (I)   <IMAGE> (I)  in which m represents 0 or 1; n represents 1, 2, 3 or 4; R1 represents hydrogen or methyl; R2 represents hydrogen, methyl or an alkanoyl group of the general formula COR' in which R' represents a hydrogen atom or a linear or branched C1-C4-alkyl group, or an alkoxycarbonyl group of the general formula COOR'' in which R'' represents a linear or branched C1-C4-alkyl group; and Ar represents either a phenyl group optionally carrying one or two substituents selected from halogen, C1-C4 alkyl, methoxy and trifluoromethyl, or a naphthalen-1-yl or naphthalen-2-yl group optionally carrying a substituent selected from halogen, methyl, methoxy and cyclopropylmethoxy groups, in the form of a cis- or trans-stereoisomer, and in the form of a free base or an acid addition salt thereof and its therapeutic use.
Patent DK-0448507-T3 (DK)
Inventor: GRAF ULRICH
IPC: G06K17/00
Filed: 1991-02-08
Granted: 1996-01-02
Abstract: To extend the range and the possibilities of application for the contactless transmission of identification from a normalised chip-carrying identification medium (1.1), for example a credit card or a key, a method is proposed which makes use of a relay station (3) between the identification medium (1.1) and the reader (2.2). The relay station (3) receives the identification signals (A) of the identification medium (1.1), decodes them, if necessary, for a specific reader (2.2) and retransmits them with a greater range. So that the normalised identification medium (1.1) can be used for short-distance (Fig. 1a) and long-distance applications (Fig. 1b) and so that the relay station (3) can be used for identification media (1.1) having different identification and/or different shape, the relay station (3) is designed in such a manner that the identification medium (1.1) can be attached to it in an interchangeable manner. <IMAGE>
Patent DK-0507874-T3 (DK)
Inventor: SNELL THOMAS G
IPC: F23Q2/16
Filed: 1990-12-21
Granted: 2001-01-02
Abstract: A selectively actuatable child resistant lighter device is disclosed which includes a body defining reservoir for containing a combustible gaseous medium such as butane, and having a valve arranged to be selectively actuated between a normally closed position and an open position which permits the exit of the gaseous medium. Such child resistant lighter can selectively produce sparks at a location proximate to the gaseous medium exit to ignite the gaseous medium. A safety mechanism normally prevents actuation of the valve to the open position. Such child resistant lighter device embodies a resiliently releasable safety latch which prevents the actuation of the valve actuator to the open position. The safety latch is selectively movable to a plurality of positions out of interference with the valve actuator, so that the gaseous medium may be released and ignited by the sparks. The safety latch is resiliently structured and mounted such that once a flame is produced and the valve actuator is released, the safety latch returns to its closed or locked position to prevent actuation of the valve to the open position by prevention of the pivotal motion of the valve actuator. To "re-use" the lighter, the safety latch must again be moved to one of the open or unlocked positions so that the valve actuator can be opened for subsequent ignition of the gaseous medium. Such mechanism is difficult for a young child to light, but is capable of actuation by adults.
Patent DK-0526540-T3 (DK)
Inventor: KAUMANN ALBERTO JULIO
IPC: A61K9/48
Filed: 1991-04-24
Granted: 1999-11-22
Abstract: The use of cardiac 5-HT4 receptor antagonists in the treatment of atrial arrythmias and for reducing the occurrence of stroke.
Patent DK-0545853-T3 (DK)
Inventor: AEBI THOMAS
IPC: A47J31/36
Filed: 1992-10-06
Granted: 1994-09-26
Abstract: In an espresso coffee machine which mainly comprises a housing (30), a fresh water container (1), a water heater (2), a pump (3), a plunger motor (4), a plunger (5) for compressing the ground coffee (10), a brewing chamber (12) for receiving the ground coffee (10), and a hot plate (7), the motor required for driving the plunger (5) is designed as a direct-current motor (4). In order to allow a simple connection of this direct-current plunger motor (4) to the mains supply, a protective resistor (6), together with a diode, is connected in series with the direct-current plunger motor (4). The protective resistor (6) serves, on the one hand, for limiting the voltage which is present above the direct-current plunger motor (4) and, on the other hand, as a heating element (16) for a hot plate (7). This hot plate (7) serves for prewarming coffee cups (25). The protective resistor (6) can additionally be actuated as a heating element (16) without the direct-current plunger motor (4) being operational so that the coffee cups (25) can be prewarmed irrespective of the operational state of the coffee machine. 
<IMAGE>
Patent DK-0563093-T3 (DK)
Inventor: THOMA HANS A
IPC: A61P1/16
Filed: 1991-12-19
Granted: 1999-02-08
Abstract: A combination, comprising at least one polypeptide sequence, mediating the antigenicity of one or more epitopes, and a carrier, capable of presenting this/these polypeptide sequence(s), which are useful for the production of a medicament for the treatment of chronic viral hepatitis, is provided.
Patent DK-0570404-T3 (DK)
Inventor: SCHNEIDER REINHARD
IPC: C08J3/12
Filed: 1992-02-03
Granted: 1997-06-02
Abstract: Agglomerated polymer particles of finely divided, water-soluble or water-swellable polymers are prepared by azeotropic dewatering of water-in-oil emulsions of water-soluble or water-swellable polymers in the presence of from 1 to 40% by weight, based on the polymers, of polyalkylene glycols which (a) are obtainable by an addition reaction of C2-C4-alkylene oxides with alcohols, phenols, amines or carboxylic acids and (b) contain not less than 2 polymerized alkylene oxide units and isolation of the agglomerated polymer particles. The water-soluble agglomerated polymer particles are used as flocculants and retention and drainage aids, while the water-swellable polymer powders are employed as thickeners for aqueous systems, in particular as thickeners for textile print pastes.
Patent DK-0577171-T3 (DK)
Inventor: VAN BELLE HERMAN
IPC: A61K31/495
Filed: 1990-11-19
Granted: 2002-06-03
Abstract: The compound (l)-(-)-2-(aminocarbonyl)-N-(4-amino-2,6-dichlorophenyl)-4-[5,5-bis(4- fluorophenyl)pentyl]-1- piperazineacetamide, the pharmaceutically acceptable acid addition salts thereof or hydrates thereof; <CHEM> a process of preparing said compound and pharmaceutical compositions comprising said compound as an active ingredient.
Patent DK-0580459-T3 (DK)
Inventor: GOUBET FRANCOIS
IPC: C07D233/84
Filed: 1993-05-28
Granted: 2001-06-11
Abstract: The subject of the invention is the products of formula (I): <IMAGE>  in which:     R1 represents cyano, nitro or halogen,   R2 represents trifluoromethyl or halogen,   the -A-B- group is chosen from the radicals <IMAGE>  in which X represents oxygen or sulphur and R3 is chosen from:     - a hydrogen, - alkyl, alkenyl, alkynyl, aryl or arylalkyl, these radicals optionally being substituted,   - trialkylsilyl,   - acyl or acyloxy,     Y represents oxygen or sulphur or NH,  with the exception of the products in which:  the -A-B- group represents the radical <IMAGE> in which X represents oxygen, R3 represents hydrogen, Y represents oxygen or NH, R2 represents halogen or trifluoromethyl and R1 represents nitro or halogen; the preparation and their application as medicaments, in particular as antiandrogens.