baber/WOPTO huggingface dataset:
Patent NZ-330816-A (NZ)
Title: Quinazoline derivatives as antitumor agents
Inventor: BARKER ANDREW JOHN
IPC: A61P35/00
Filed: 1997-02-10
Abstract: Quinazoline derivative of the formula 1 wherein X1 is a direct link or a group such as CO, C(R2)2 and CH(OR2); Q1 is phenyl, naphthyl or a 5- or 6-membered heteroaryl moiety and Q1 optionally bears up to 3 substituents; m is 1 or 2; each R1 may be a group such as hydrogen, halogen and trifluoromethyl; Q2 may be phenyl or a 9- or 10-membered bicyclic heterocyclic moiety and Q2 optionally bears up to 3 substituents; or a pharmaceutically acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and the use of their receptor tyrosine kinase inhibitory properties in the treatment of proliferative disease such as cancer.
Patent NZ-331912-A (NZ)
Title: Hands-free paper towel dispenser with electronic feed controlled by photovoltaic cells
Inventor: BYRD DANNIE D
IPC: A47K10/36
Filed: 1997-02-13
Abstract: hands-free towel dispenser (10) comprising: a housing means (12) for containing towels; a sensing means (82) for detecting an object such as a person's hands; a dispensing means for dispensing a towel when said sensing means detects the object; an electric power source (90) for powering said dispensing means; control circuitry (98) for controlling the dispensing means; and a light sensor panel (96) for energizing said control circuitry. Preferably, the sensing means (82) comprises a motion detector which senses rapid changes in light. Also, preferably, the source of electric power is a battery which is in turn energized by the light sensor panel.
Patent NZ-334862-A (NZ)
Title: Synergistic composition containing an ionene polymer and a metal pyrithione salt for preventing spoilage caused by microorganisms
Inventor: OPPONG DAVID
IPC: A01N43/40
Filed: 1997-09-26
Abstract: Compositions comprising an ionene polymer and a pyrithione salt, wherein the two components present in a combined amount synergistically effective to control the growth of microorganisms such as bacteria, fungi, algae or mixtures thereof. The ionene polymer comprises the repeating unit of Formula (I); wherein R1, R2, R3 and R4 are identical or different, and are selected from hydrogen, C1-20alkyl and benzyl; A is a divalent radical selected from C1-10alkyl, C2-10alkenyl, C2-10alkynyl, C1-10hydroalkyl, symmetric or asymmetric di-C1-10alkylether, aryl, arylC1-10alkyl and C1-10alkylarylC1-10alkyl; B is a divalent radical selected from C1-10alkyl, C2-10alkenyl, C2-10alkynyl, C1-10hydroxyalkyl, symmetric or asymmetric di-C1-10-alkylether, aryl, aryl-C1-10alkyl, or C1-10alkylaryl-C1-10-alkyl; and X2- is a divalent counter ion, two monovalent counter ions, or a fraction of a polyvalent counter ion sufficient to balance the cationic charge in the repeating unit which forms the ionene polymer backbone. The preferred pyrithione salt is sodium pyrithione, zinc pyrithione, copper pyrithione, aluminium pyrithione or magnesium pyrithione.
Patent NZ-334966-A (NZ)
Title: Substituted arylalkylamines as neurokinin antagonists
Inventor: REICHARD GREGORY A
IPC: C07D211/52
Filed: 1996-10-28
Abstract: A compound represented by the structural formula I or a pharmaceutically acceptable salt thereof, wherein;  A1 is OR6, N(R6)(R7), S(O)eR13 or (C(R6)(R7))1-6N(R6)(R7) and A2 is H, or A1 and A2 together are O, C(R6)(R7) or NOR6, Q is R5-phenyl, T is R4-aryl, b is 0, 1 or 2, b1 is 1 or 2, X is O, NR6, N(R6)C(O), OC(O)NR6 or N(R6)C(O)O, R4 and R5 are independently 1-3 substituents independently selected from the group consisting of H, halogeno, OR6, OC(O)R6, OC(O)N(R6)(R7), N(R6)(R7), C1-6 alkyl, CF3, C2F5, COR6, CO2R6, CON(R6)(R7), S(O)eR13, CN, OCF3, NR6CO2R16, NR6COR7, NR8CON(R6)(R7), R15-phenyl, R15-benzyl, NO2, N(R6)S(O)2R13 or S(O)2N(R6)(R7) or adjacent R4 substituents or adjacent R5 substituents can form a OCH2O group and R4 can also be R15-heteroaryl, R6, R7, R8, R8a, and R13 are independently selected from the group consisting of H, C1-6 alkyl, C2-C6 hydroxyalkyl, C1-C6 alkoxy-C1-C6 alkyl, R15-phenyl, and R15-benzyl or R6 and R7, together with the nitrogen to which they are attached, form a ring of 5 to 6 members, wherein 0, 1 or 2 ring members are selected from the group consisting of O, S and N(R19), R9 and R9a are independently selected from the group consisting of R6 and OR6, provided that when R9 is OH, X is N(R6)C(O), R10 is independently selected from the group consisting of H and C1-6 alkyl, R15 is 1 to 3 substituents independently selected from the group consisting of H, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylthio, halogeno, CF3, C2F5, COR10, CO2R10, C(O)N(R10)2, S(O)eR10, CN, N(R10)COR10, N(R10)CON(R10)2 and NO2, R16 is C1-6 alkyl, R15-phenyl or R15-benzyl, R19 is H, C1-C6 alkyl, C(O)N(R10)2, CO2R10, (C(R8)(R9))fCO2R10 or (C(R8)(R9))uC(O)N(R10)2, f is 1-6, u is 0-6, Z is formula II or formula III, g is 1, j is 1 or 0, h is 2, k is 2 or 3, J is two hydrogen atoms or O, L is H, C1-C6 alkyl, C1-C6 alkenyl, CH2 cycloalkyl, R15-benzyl, R15-heteroaryl, C(O)R6, (CH2)mOR6, (CH2)mN(R6)(R7), (CH2)mC(O)OR6 or (CH2)mC(O)N(R6)(R7), L1 is H, R28 is H, OH, phenyl or H2NC(O) and R29 is H or R4-phenyl.  The abovementioned compounds are useful in the treatment of asthma, cough, bronchospasm, central nervous system diseases, inflammatory diseases and gastrointestinal disorders.
Patent NZ-335103-A (NZ)
Title: Soluble proteins
Inventor: PRUSINER STANLEY B
IPC: A61P25/28
Filed: 1997-04-15
Abstract: The deleting codon segments from DNA expressing a native protein (e.g., PrPSc) in order to obtain a shorter, soluble protein that mimics characteristics of an insoluble native (e.g., PrPSc) protein. Soluble proteins are obtained by providing a DNA sequence which encodes a native protein and systematically removing codons, making copies of the shortened versions of DNA which are then expressed to provide the shortened proteins. The shortened proteins are then tested for solubility. Soluble proteins are then further tested to confirm that they retain the biological characteristics of the native protein. The soluble form can also be created by adding amino acids, binding a hydrophilic moiety to the native protein or combinations of deleting, adding, and binding hydrophilic moieties to the protein
Patent NZ-501400-A (NZ)
Title: Spinal three-dimensional orthopedic apparatus with driven hip and leg boards and a low speed draught device
Inventor: ZHANG JILIN
IPC: A61F5/048
Filed: 1997-04-29
Abstract: A spinal three-dimensional orthopedic apparatus (1) comprising a mounting frame, a cephalothoracic board and driving device thereof, a hip-leg board and driving device thereof, a low speed draught device, hip board and a driving device thereof, and patient securing means. The cephalothoracic board is capable of longitudinal movement in the X-axis, the hip-leg board is capable of rotational movement about the X and Y-axes and the hip board is capable of rotational movement of the Z-axis. The hip-leg board and hip board are capable of high-speed oscillatory movement. The driving devices employed are high-speed electromagnetic drives. A clutch is provided for linking up the high-speed movement of the cephalothoracic board with the low speed movement of the draught device.
Patent NZ-502281-A (NZ)
Title: 2-aminopyridines containing fused ring substituents as nitric oxide synthase (NOS) inhibitors
Inventor: LOWE JOHN ADAMS
IPC: A61K31/443
Filed: 1998-08-11
Abstract: Described are 2-aminopyridine derivatives of formula (I) wherein ring A is a fused 5-7 membered saturated or unsaturated ring wherein from zero to two of the ring members are heteroatoms selected, independently, from nitrogen, oxygen and sulphur, with the proviso that no two adjacent ring members can both be heteroatoms; X is oxygen or a bond; n is an integer from two to six; and R1 and R2 are selected, independently, from (C1-C6) alkyl, aryl, tetrahydronaphthalene and aralkyl, wherein said aryl and the aryl moiety of said aralkyl is phenyl or naphthyl and the alkyl moiety is straight or branched and contains from 1 to 6 carbon atoms, and wherein said (C1-C6) alkyl, said aryl, said tetrahydronaphthalene and the aryl moiety of said aralkyl may optionally be substituted with from one to three substituents, preferably from zero to two substituents, that are selected, independently, from halo (eg, chloro, fluoro, bromo, iodo), nitro, hydroxy, cyano, amino, (C1-C4) alkoxy, and (C1-C4) alkylamino; or R1 and R2 form, together with the nitrogen to which they are attached, a piperazine, azetidine, piperidine or pyrrolidine ring or an azabicyclic ring containing from 6 to 14 ring members, from 1 to 3 of which are nitrogen and the rest of which are carbon. These derivatives exhibit activity as nitric oxide synthase (NOS) inhibitors and also described are pharmaceutical compositions containing them and to their use in the treatment and prevention of central nervous system and other disorders.
Patent NZ-502403-A (NZ)
Title: Device for controlling an angularly movable member, such as overhead door closers and floor springs
Inventor: LAW BRIAN ROBERT
IPC: E05F3/22
Filed: 1998-06-17
Abstract: Provided is a control mechanism for use with a door closer having a pinion shaft (18), comprises a coiled torsion spring (22) around the shaft with a free end of the spring lying along part of a strap (29), which strap is connected to the shaft and normally held in tension, in use, by its connection to a movable hydraulic piston of the door closer which is biased in one direction. On normal closing of the door, in use, the strap remains tensioned and the spring (22) is thus prevented from tightening on the shaft.  However, if an additional, i.e. external, closing force is applied to the door, the strap becomes untensioned, thereby allowing the spring to tighten about the shaft to retard its angular door closing movement.
Patent NZ-502677-A (NZ)
Title: A method for increasing incorporation efficiency of omega-3 highly unsaturated fatty acid in poultry meat
Inventor: BARCLAY WILLIAM R
IPC: A23L13/40
Filed: 1998-08-14
Abstract: A method for increasing the amount of an omega-3 highly unsaturated fatty acid (HUFA) in the meat of poultry comprising feeding a feed to poultry, where the feed contains a source of omega-3 HUFA, and the feed omega-3 HUFA content is higher in a later phase of poultry's production period than in an earlier phase, and the amount of any low quality omega-3 HUFA source oil is less than 2 percent by weight of the feed.  The source of omega-3 HUFA can be a marine microorganism, a microorganism of the order thraustochytriales and low quality omega-3 HUFA source can be fish meal or other residual biomass from.
Patent NZ-503798-A (NZ)
Title: Antifouling compositions comprising thiacloprid for treating infestation by sessile Entomostraca and/or sessile Oligochaetes
Inventor: KUGLER MARTIN
IPC: C09D5/16
Filed: 2000-04-05
Abstract: A method of protecting an article from infestation by sessile Entomostraca and/or sessile Oligochaetes comprising applying to or adding to the article an antifouling composition comprising thiacloprid or thiacloprid in combination with other active antifouling substances, preferably algicides, fungicides, herbicides, molluscides and/or other active antifouling substances.
Patent NZ-508393-A (NZ)
Title: Directional drilling system and apparatus
Inventor: CHANDLER ROY L
IPC: E21B7/04
Filed: 1999-06-04
Abstract: The apparatus, in one embodiment, has guide housing (113) with a shaft (101) extending through the guide housing (113) with a drill bit (105) coupled to its forward end (101F). The shaft (101) may be moved to a forward drilling position or to a rearward shifting position relative to the guide housing (113). A cam is located inside of the guide housing. A cam follower (131) is coupled to the shaft. In the shifting mode, the cam follower (131) is disengaged from the cam. A clutch (261) is provided for coupling the cam to the shaft when the shaft is in the shifting position such that the cam follower may be rotated with the shaft relative to the cam to allow the cam follower to engage the cam when the shaft is moved to the forward drilling position. In the forward drilling position of the shaft, the clutch releases the cam from the shaft and the cam follower engages the cam to allow straight drilling to occur or to cause the axis of said guide housing to shift relative to the axis of the shaft to cause the direction of drilling by the shaft and drill bit to change.
Patent NZ-508506-A (NZ)
Title: 4,5,6 and 7-indole and indoline derivatives, their preparation and use
Inventor: MOLTZEN ENJER KNUD
IPC: C07D401/14
Filed: 1999-06-14
Abstract: Indole or indoline compounds of formula (I), wherein: W is N, C, CH or COH, A is a group of formulae (II) - (VIII), and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of diseases responsive to inhibition of serotonin reuptake and antagonism of 5-HT1A receptors.
Patent NZ-508858-A (NZ)
Title: A method allowing a domestic subscriber to selectively receive an international roaming service
Inventor: KIM JIN-HONG
IPC: H04M3/00
Filed: 2000-12-13
Abstract: To provide wireless communication services to an international roaming mobile station (16), information regarding whether or not the mobile station subscribes to an international roaming service is stored in a database of the Home Location Register, HLR (22). Identification (MSC ID) regarding the Mobile Switching Centers (14) is also stored in the database. Next, determination is made to see if a registration notification (REGNOT) massage is received from an MSC of a home system (12) by checking MSC IDs from the HLR. If the REGNOT is not from a system (32) other than home system (12), message is sent to the MSC informing if the mobile station subscribes to international roaming. In addition, an international telephone service provider number for the international roaming mobile station is stored in the HLR. This number will be sent together with a routing number to the international roaming mobile station when a location request message is received at the HLR.
Patent NZ-509644-A (NZ)
Title: Seedless tomato and method for producing seedless tomato and hybrid tomato plants capable of producing said seedless tomatoes
Inventor: VAN VLIET GERARDUS JOHANNES AL
IPC: A01H5/10
Filed: 2000-06-05
Abstract: A method for producing a hybrid plant capable of carrying seedless tomatoes, wherein the method comprises the steps of: (a) Providing a seedless tomato line that is homozygous for a recessive gene for parthenocarpy and homozygous for a recessive gene for functional sterility; (b) Providing a first non-seedless tomato line with a first genotype that is capable of heterosis with a second genotype; (c) Crossing the seedless tomato line provided in (a) with the non-seedless line provided in (b) to provide a first non-seedless F1 generation of plants; (d) Causing the plants from the non-seedless F1 generation to self-pollinate to provide a F2 generation of plants; (e) Selecting from the F2 generation plants with a seedless phenotype and causing the selected seedless plants to self-pollinate to provide a F3 generation of plants; (f) Selecting plants with a seedless phenotype from the F3 or a further generation and causing the selected seedless plants to self-pollinate to provide a new further generation of seedless plants; (g) Repeating step (f), until a F5 or further generation of seedless plants is obtained that provides completely seedless offspring; (h) Providing a second non-seedless tomato line with a genotype that is capable of heterosis with the first genotype in (b); (i) Crossing the second non-seedless tomato line provided in (h) with the seedless tomato line as provided in (a) to provide a second non-seedless F1 generation of plants; (j) Repeating steps (d) to (g) with the second non-seedless F1 generation of plants obtained in (i) to provide a second F5 or further generation of seedless plants that is genetically homogeneous in that it provides completely seedless offspring; (k) Crossing the first F5 or further generation of seedless plants obtained in (g) with the second F5 or further generation of seedless plants obtained in (j) to provide a hybrid tomato plant capable of carrying seedless tomatoes.
Patent NZ-510508-A (NZ)
Title: Method for down-regulating osteoprotegerin ligand (OPGL) by enabling the production of antibodies against OPGL to treat osteoporosis
Inventor: HALKIER TORBEN
IPC: C12N15/09
Filed: 1999-09-13
Abstract: Described is a method for down-regulating the biological activity of osteoprotegerin ligand (OPGL, TRANCE) thereby rendering possible the treatment/amelioration of diseases characterized by excessive loss of bone mass, e.g. osteoporosis. Down-regulation is affected by inducing an immune response against OPGL in an individual in need thereof. Immune responses can be raised by classical immunization with immunogenic variants of OPGL or by nucleic acid immunization where the nucleic acids encode the OPGL variant. Also described are compositions, polypeptides and nucleic acids, as well as vectors and transformed host cells used in the preparation thereof.
Patent NZ-513005-A (NZ)
Title: Method for diagnosing and distinguishing stroke
Inventor: JACKOWSKI GEORGE
IPC: C12Q1/00
Filed: 2000-02-22
Abstract: A method for diagnosing and distinguishing stroke by analysing the body fluid of a patient to detect the presence and concentration of four markers of stroke wherein a first marker is myelin basic protein, a second marker is the beta isoform of S100 protein, a third marker is neuronal specific enolase, a fourth marker is a brain endothelial cell membrane protein; and from the information obtained determine whether an ischaemic or haemorrhagic cerebral event has occurred.  Also detailed is a diagnostic kit using antibodies specific for each of the four named marker proteins.
Patent NZ-515201-A (NZ)
Title: System and method for private and secure financial transactions
Inventor: MIZRAH LEN L
IPC: G06Q40/00
Filed: 2001-11-01
Abstract: A system and method for private and secure financial transactions comprises embedding into financial institutions (financial institution) privacy and security layer architecture and the "clocked" authentication, authorization and accounting (AAA) method. The system and method enable legal financial account holders (financial account holder) to perform buy/sell or withdraw/deposit financial transactions (financial transaction) without disclosing private personal information to the transaction counterparts, while preserving highly elevated and enhanced security and fraud protection as compared with conventional methods. Before financial transaction, financial account holder initiates an authentication session with financial institution back office (financial institution back office) by accessing its central processing unit (CPU) and data base (dB), configured in the embedded privacy and security layer (EPSL) architecture with automated "clocked" AAA sessions by using dedicated communication lines. The authentication session is interactive, transaction specific and followed by either financial transaction deny or an alphanumeric signature generated for this specific financial transaction . Then financial account holder submits his/her request to a transaction counterpart along with the EPSL account number and the alphanumeric signature, generated by financial institution EPSL during previous authentication session. The transaction counterpart adds up additional or more refined financial transaction specific information and requests an authorization session with financial institution back office where the EPSL account, CPU and dB are residing. The accounting session starts at the end of the authentication session and finishes along with the authorization session while being an essential part of them both. The system and method are particularly suited for use by banks, credit card companies and brokerage companies. Finally, the system and method are well adapted to the current and upcoming software, hardware, and electronic commerce technologies and can be easily implemented given an acceptable business trade off.
Patent NZ-516397-A (NZ)
Title: Aminothiazole derivatives and their use as CRF receptor ligands
Inventor: FONTAINE EVELYNE
IPC: A61P25/00
Filed: 2000-07-11
Abstract: Aminothiazole compounds of formula (I.2) are described, for which the substituents are defined herein. The compounds re used in the manufacture of medicaments for the treatment of diseases mediated by corticotropin releasing factor (CRF) activity.
Patent NZ-517421-A (NZ)
Title: Product-structurant composition for personal care formulations
Inventor: REREK MARK
IPC: A61K8/40
Filed: 2000-04-11
Abstract: A flake composition, which will form a bilayer lamellar gel network when placed in an oil-in-water system consisting essentially of: i) A cationic swellant which is a saturated fatty acid selected from stearic or palmitic acid, or mixtures thereof in an adduct of amidopropyldimethyl-2-hydroxyethyl ammonium halide. ii) A gellant blend of low HLB emulsifiers which includes a saturated fatty alcohol, the gellant blend having a resultant HLB of 1.5 to 4.5 The adduct described in i) is made in the saturated fatty acid as solvent.
Patent NZ-517470-A (NZ)
Title: Mesoprogestins (progesterone receptor modulators) as a component of female contraceptives
Inventor: CHWALISZ KRISTOF
IPC: A61P15/18
Filed: 2000-08-31
Abstract: Use of a mesoprogestin selected from J 867, J 1042, J 900 and J 914 as a component for the production of a pharmaceutical for female contraception.
Patent NZ-521865-A (NZ)
Title: Compositions and methods for the therapy and diagnosis of breast cancer
Inventor: JIANG YUQIU
IPC: A61K35/12
Filed: 2001-04-12
Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as breast cancer, are disclosed. Compositions may comprise one or more breast tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a breast tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as breast cancer. Diagnostic methods based on detecting a breast tumor protein, or mRNA encoding such a protein, in a sample are also provided.
Patent NZ-523799-A (NZ)
Title: Anti-angiogenic compositions and methods of use
Inventor: BURT HELEN M
IPC: A61K47/42
Filed: 1994-07-19
Abstract: A composition, comprising (a) a compound which disrupts microtubule function, with the proviso that said compound is not paclitaxel, or an analogue or derivative thereof; and (b) a polymer, with the proviso that said polymer is not a capsule or a polyanhydride.
Patent NZ-524272-A (NZ)
Title: Optical disk with printed label covering chucking portion
Inventor: ITO TOMOAKI
IPC: G11B7/24012
Filed: 2001-09-13
Abstract: An optical disk that has a printed label on its upper surface which also covers the chucking portion is disclosed. The disk includes transparent synthetic resin disk substrate having a centre hole for chucking 5, a clamping area 6 around the centre hole 5 and an elastic film for label printing 10 fixed to the upper surface of the disk substrate so as to close the centre hole. The film 10 is not fixed to the chucking area 5,6 and when a disk chuck is inserted this portion of the film expands and is pushed up by the chuck. When the chuck is retracted the film returns to its original flat state.
Patent NZ-526098-A (NZ)
Title: Use of a plant extract containing flavonoids rich in proanthocyanidins for the prevention or treatment of migraine
Inventor: STENSWICK LARRY ELLSWORTH
IPC: A61P25/06
Filed: 2003-05-23
Abstract: Use of a plant extract that includes a therapeutically effective dose of a mixture of flavonoids rich in proanthocyanidins in the manufacture of a medicament for the prevention and treatment of migraine is disclosed. The source of the plant extract may include bark of a plant such as pine bark (Pinus radiata bark), grape seeds, green tea, etc., that have a mixture of flavonoids rich in proanthocyanidin.