baber/WOPTO huggingface dataset:
Patent NO-166364-B (NO)
Inventor: CLAUSS KARL
IPC: A23L27/30
Filed: 1985-11-18
Abstract: 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide is prepared by (a) reacting, in an inert organic solvent, a salt of sulfamic acid, which is at least partially soluble therein, with at least approximately the equimolar amount of an acetoacetylating agent, in the presence of an amine or phosphine catalyst, and by cyclizing the acetoacetamide-N-sulfonate which is formed in this reaction, or the free sulfonic acid, (b) by the action of at least approximately the equimolar amount of SO3, where appropriate in an inert inorganic or organic solvent, to give 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide, which is produced in the form of the acid in this reaction; it is possible, if desired, to obtain from the acid form (c) the appropriate salts by neutralization with bases. The non-toxic salts - in particular the potassium salt - are valuable synthetic sweeteners.
Patent NO-166409-B (NO)
Inventor: PINZA MARIO
IPC: C07K5/06
Filed: 1986-06-20
Abstract: Compounds of Structure (1): 
<CHEM>
 in which
 R<1> is H, C1-5 alkyl (straight or branched), or phenyl;
 W is a bond, -NHC.HR<6>CO- or -NHCHR<6>CONH-CHR<7>CO-, where R<6> and R<7>, which can be the same or different are H or C1-5 alkyl (straight or branched);
 R<2> is H, C1-5 alkyl (straight or branched), aryl or a benzyl group optionally substituted by C1-5 alkyl (straight or branched), C1-4 akoxy (straight or branched) or hydroxy;
 R<3> and R<4>, which can be the same or different, are H, C1-5 alkyl (straight or branched) or phenyl, or R<3> and R<4> can together form a 1,4-butylene or 1,5-pentylene group;
 R<5> is H or -CHR<8>CONR<9>R<1><0>, where R<8>, R<9> and R<1><0>, which can be the same or different, are H or C1-5 alkyl (straight or branched);
 R<1><1> and R<1><2>, which can be the same or different, are H, C1-5 alkyl (straight or branched), or acyl or together with the nitrogen atom shown form a 2-oxo-pyrrolidino group optionally substituted in the 4-position by a hydroxy or C1-5 (straight or branched) alkoxy group, or a 5-oxo-1-imidazolidine group optionally substituted at the 2- position by one or two C1-5 alkyl groups or a 1,4-butylene or 1,5-pentylene group, or optionally substituted at the 4-position by C1-5 alkyl,
 or a pharmaceutically acceptable salt thereof, processes and intermediates for making them, pharmaceutical compositions containing them and their use as nootropic agents.
Patent NO-166436-B (NO)
Inventor: BERG LARS OLOF
IPC: B62D27/06
Filed: 1987-11-03
Abstract: A platform stanchion (13) easily lockable to the edge of the platform (10) of a truck has a canvas cover-supporting post (17) consisting of an upper pole (26) and a lower U-section (25) connected thereto. The stanchion (13) engages with the post (17) by means of a tapered upper portion (23) with a tongue at its top. For receiving the upper portion (23) of the stanchion, the U-section (25) of the post (17) has a mating tapered recess with an opening at the top for receiving the tongue. The stanchion (13) and the post (17) can be pivoted inwards and outwards relative to each other with the tongue located in the opening of the U-section serving as pivotal centre. In the swung-in position with the stanchion (13) and the post (17) aligned with each other, the stanchion is accommodated in the U-section of the post. Holes (33) provided in the flanges of the U-section are then located opposite the catches (15) which can be pivoted out of the stanchion (13) for locking the platform sides, whereby the canvas cover-supporting post (17) and the platform sides can be locked at the same time by means of the catches.
Patent NO-172874-B (NO)
Inventor: STOECKLI RUDOLF
IPC: G07D9/00
Filed: 1988-06-03
Abstract: Coins (24) lying on a turntable (22) driven in the direction of rotation (20) are forced by centrifugal force into a discharge channel (30) whose height limits the permissible thickness of the coins. Coins fed from the discharge channel (30) are rolled off with an S-shaped movement at a roll-off lip (38) when picked up by a conveyor belt (40) acting from above and are then conveyed away in a straight direction (42). The S-shaped movement is impressed on the coins (24c) by the arrangement of components (36, 38) which limit an exit opening (28) and which also include the roll-off lip (38). Such an arrangement ensures a reliable and trouble-free separation with few moving parts. 
<IMAGE>
Patent NO-167003-B (NO)
Title: Innretning for behandling av glideflater paa vintersportsutstyr
Inventor: KUENZLER PETER
IPC: A63C11/08
Filed: 1989-02-06
Abstract: Det beskrives en Innretning som muliggjør en frem-gangsmåte for behandling av glideflater (4) på vlntersportsutstyr (2). Vlntersportsutstyret (2) fastholdes med glideflaten (4) vendt oppover. Behandlingen skjer ved hjelp av en oppvarmbar plate (18) med en porøs Innsats (42), idet platen kan legges fjærende an mot glideflaten (4) og forskyves relativt denne i lengderetningen. Innsatsen (42) kan fra et kar (48) oppta et i det minste til pastøs tilstand oppvarmbart middel (50). En lager innretning (44) for et porøst bladmaterlale (46) kan levere bladmaterialet mellom den oppvarmbare plate (18) og glideplaten (4). Behandlingen kan innbefatte fjerning av rester av gammelt middel fra glideflaten, idet slike rester suges opp av bladmaterialet. Behandlingen kan også Innbefatte en forvarming av glideflaten. I så tilfelle kan platen brukes for bestryking av glideflaten uten bladmateriale. Påføring av nytt middel fra karet er også mulig, idet herunder bladmaterialet vil muligjøre en finfordeling. Middelet vil trenge inn i mlkrokaviteter i glldeflatebelegget og fylle ut eventuelle rift eller oppskrapinger, slik at det dannes et glatt, plant og elastisk sjikt på glideflaten.()nforte publikasjoner BRD (DE) uti. skrift nr. 1192558,. Sveitsisk (CH) patent nr. 656071,. Østerriksk (AT) patent nr. 364732.
Patent NO-172893-B (NO)
Inventor: YAMANAKA HIDEAKI
IPC: C07D501/46
Filed: 1989-06-05
Abstract: A compound of the formula : <CHEM>  wherein  R<1> is amino or a protected amino group,  Z is N or CH,  R<2> is an organic group, and  R is a group of the formula : <CHEM>  (in which  R<3> and R<4> are each lower alkyl, or  R<3> and R<4> are linked together to form C3-C6 alkylene,  A is lower alkylene, and  R<5> is hydroxy or a protected hydroxy group)  or a group of the formula : <CHEM>  (in which  R<6> is lower alkyl,  R<7> and R<8> are each hydroxy or a protected hydroxy group, and  Y is N or CH),  and a pharmaceutically acceptable salt thereof, processes for their preparation and pharmaceutical compositions comprising them as an active ingredient. The invention relates also to intermediates of the formula <CHEM> and their preparation. o
Patent NO-179468-B (NO)
Inventor: SAWADA TAKASHI
IPC: G01N33/531
Filed: 1990-09-03
Abstract: The assay method comprises the steps of adding a serum specimen to a solid phase at a pH value of 9 to 10 and assaying an antibody in the specimen. The antibody may be adult T cell leukemia virus antibody (HTLV-I antibody).
Patent NO-180607-B (NO)
Inventor: OSTERMANN WERNER
IPC: H01H73/18
Filed: 1991-02-22
Abstract: In the automatic cutout having an electromagnetic trip (3) designed as an impact armature system, an energising winding (3a) is surrounded by a frame-shaped magnet yoke (5) formed by a ferromagnetic sheet-metal strip. Said yoke has an integrally arranged, horn-shaped fixed contact point (5d), which merges into an arc guide rail (5f) and interacts with a moving contact lever (8), which is arranged on the side of the trip (3) and in front of the end of an arc splitter stack (4a). In order structurally to simplify the magnet yoke (5), and to construct it in a material-saving manner, it is folded from one piece to form a frame-shaped closed iron return path surrounding the energising winding (3a). To this end, the magnet yoke (5) has a U-limbed region (5a, 5b, 5c), which is located above and on both end surfaces of the energising winding (3a) and is constructed at one limb end, together with the contact horn (5e), with a fixed contact point (5d), which is arranged without a transition and projects in the form of an ear. Connected thereto is a bent-back arc guide rail (5f) which, with the end of the free limb (5a), forms a rectangular frame corner without mutual contact, so that the shape of the magnet yoke (5), which is folded in one piece is completed. <IMAGE>
Patent RS-49836-B (RS)
Inventor: LEHNER SHELTON RICHARD
IPC: C07D405/00
Filed: 2000-03-03
Abstract: Postupak za dobijanje jedinjenja Formule I: ili njegove farmaceutski prihvatljive soli ili solvata gde su: R1 i R2 , svaki nezavisno odabrani od C1-C10alkil i C1-C10alkoksi, gde su dati alkil i alkoksi po potrebi supstituisani sa do dva supstituenta nezavisno odabrana od hidroksi i C1C6alkoksi; R15 je H, C1-C10alkil ili –(CH2)q(C6-C10aril), gde je q broj od 0 do 4; naznačen time, što obuhvata reakciju jedinjenja Formule 2.: gde su R15, R1 i R2 kao što je prethodno definisano i G je blokirajuća grupa-C(OH)R3R4; R3 i R4 su svaki nezavisno C1-C6alkil; sa alkalnim metalom ili hidroksidom alkalnog metala u rastvaraču koji obuhvata hidroksi supstituisan C1-C10alkil.
Patent RS-52394-B (RS)
Inventor: SOMMADOSSI JEAN-PIERRE
IPC: C07H19/167
Filed: 2001-05-23
Abstract: Upotreba jedinjenja Formule II:ili njegove farmaceutski prihvatljive soli, u proizvodnji leka za lečenje domaćina koji je inficiran virusom hepatitisa C, gde:R1 R2 i R3 nezavisno su H; fosfat; estar karboksilne kiseline u kome je ne-karbonil grupa estarske grupe izabrana od zasićenog pravolančanog, granatog ili cikličnog primarnog, sekundarnog ili tercijarnog ugljovodonika od C1 do C10, metoksimetila, benzila, fenoksilmetila, fenila izborno supstituisanog sa hloro, bromo, fluoro, jodo, C1 do C4 zasićenog pravolančanog, granatog ili cikličnog, primarnog, sekundarnog ili tercijarnog ugljovodonika, C1 do C4 alkoksi, sulfonatnog estra, metansulfonila, mono-, di- ili tri-fosfatnog estra; tritila ili monometoksitritila, supstituisanog benzila, trialkilsilila ili difenilmetilsilila; zasićeni pravolančani, granati ili ciklični, primarni, sekundarni ili tercijarni ugljovodonik od C1 do C10; sulfonatni estar uključujući zasićeni pravolančani, granati ili ciklični, primarni, sekundarni ili tercijarni ugljovodonik od C1 do C10 sulfonil ili fenil, bifenil ili naftil supstituisan sa zasićenim pravolančanim, granatim ili cikličnim, primarnim, sekundarnim ili tercijarnim ugljovodonikom od C1 do C10 sulfonil uključujući metansulfonil i benzil, gde je fenil grupa opciono supstituisana sa jednim ili više supstituenata koji su izabrani iz grupe koju čine hidroksil, amino, (zasićeni pravolančani, granati ili ciklični, primarni, sekundarni ili tercijarni ugljovodonik od C1 do C10)amino, (fenil, bifenil ili naftil)amino, (fenil, bifenil ili naftil)oksi, nitro, cijano, sulfonska kiselina, sulfat, fosfonska kiselina, fosfat, fosfonat ili zasićeni pravolančani, granati ili ciklični, primarni, sekundarni ili tercijarni ugljovodonik od C1 do C10;lipid, uključujući fosfolipid; aminokiselina; ugljeni hidrat; peptid; holesterol; Y je vodonik, bromo, hloro, fluoro, jodo, OR4, NR4R5 ili SR4;X1 i X2 su nezavisno odabrani iz grupe koju čine H, pravolančani, razgranati ili ciklični zasićeni primarni, sekundarni ili tercijarni ugljovodonik od C1 do C10, CO-(zasićeni pravolančani, granati ili ciklični primarni, sekundarni ili tercijarni ugljovodonik od C1 do C10, CO-(fenil, bifenil ili naftil), CO-(zasićeni pravolančani, granati ili ciklični primarni, sekundarni ili tercijarni ugljovodonik od C1 do C10)oksi(zasićeni pravolančani, granati ili ciklični primarni, sekundarni ili tercijarni ugljovodonik od C1 do C10), hloro, bromo, fluoro, jodo, OR4, NR4R5 ili SR4; iR4 i R5 su nezavisno vodonik, estar karboksilne kiseline u kome je ne-karbonil grupa estarske grupe izabrana od zasićenog pravolančanog, granatog ili cikličnog, primarnog, sekundarnog ili tercijarnog ugljovodonika od C1 do C10, metoksimetila, benzila, fenoksimetila, fenila izborno supstituisanog sa hloro, bromo, fluoro, jodo, C1 do C4 zasićenog pravolančanog, granatog ili cikličnog, primarnog, sekundarnog ili tercijarnog ugljovodonika, C1 do C4 alkoksi, sulfonatnog estra, metan
Patent ZA-811305-B (ZA)
Title: 2-penem compounds
Inventor: AFONSO A
IPC: C07D205/09
Filed: 1981-02-26
Abstract: The present invention relates to compounds of the formula 
<CHEM>
 wherein n is 0 to 4;
 R is hydrogen, an alkali metal or quaternary ammonium cation or a metabolisable ester group;
 R1 and R2 are independently hydrogen or lower alkyl;
 R4 is hydrogen, lower alkyl or a group of the formula R5CHOH- with R5 being hydrogen, lower alkyl, aryl, aralkyl, heteroaryl or heteroaralkyl;
 R6 is amino, loweralkylamino, an  alpha -aminoacid residue bonded through the  alpha -nitrogen atom or the group -OR8 with R8 being hydrogen, lower alkyl, allyl, aryl, aralkyl, an alkali metal or quaternary ammonium cation or a metabolisable ester group;
 R7 is hydrogen, loweralkyl, loweralkoxycarbonyl, aryl, aralkyl, aralkoxycarbonyl, arylsulfonyl, acyl, or, together with the N-hydrogen, the grouping 
<CHEM>
 wherein either
 R9 is aryl and R10 is hydrogen, lower alkyl or aralkyl; or R9 is hydrogen, amino or mono- or dilower-alkylamino and R10 is amino, mono- or diloweralkyl amino, lower alkyl, aryl, aralkyl or lower alkoxycarbonyl; and 1,3-dicarbonyl adducts at the 2 min -amino group when R7 is hydrogen; to pharmaceutical compositions comprising such compounds and methods for preparing them.
Patent ZA-828369-B (ZA)
Title: New acrylic copolymers of n-acryloylpolymethyleneimines or n-acryloldialkylamides,n,n'-acryloyldiaminoalcanes and n-acryloylaminoacids (or esters) their preparation and use as cation exchangers
Inventor: ASPISI CHRISTIAN
IPC: B01J39/26
Filed: 1982-11-15
Abstract: The invention relates to new reticulated statistic acrylic copolymers that may be used in a very wide range of solvents (water, methylene chloride, chloroform, methanol, ethanol, dimethylformamide, pyridine,) stable between pH 1 and pH 14, to preparation process thereof and to their use in ion exchange chromatography.
Patent ZA-858157-B (ZA)
Title: Immunogenic complex,a method for producing the same,and the use thereof as an immune stimulant,vaccines and reagents
Inventor: MOREIN BROR
IPC: A61K39/44
Filed: 1985-10-23
Abstract: The invention relates to a process for preparing an immunogenic complex comprising a carrier molecule prepared by mixing viruses, mycoplasmas, bacterias, animal cells or proteins or peptides having hydrophobic regions with one or more solubilizing agents, whereby a complex having been formed between proteins or peptides and solubilizing agents, whereafter the proteins or the peptides have been separated from the solubilizing agent in the presence of a glycoside solution which contains one or more glycosides having hydrophobic and hydrophilic regions in a concentration of at least the critical micellular concentration, or alternatively have been separated from the solubilizing agent and transferred directly to the aforementioned glycoside solution, and the carrier molecule being bound to one or more molecules selected from peptides, proteins, carbohydrates, lipoproteins, glycolipides or small molecules, such as biotine, by coupling with known methods between functional coupling groups in the bound molecules and functional groups in the peptides or the proteins in the carrier molecule. 
<??>The invention also relates to a method for preparing such immunogenic complexes, compositions, vaccines containing such complexes and to reagents.
Patent ZA-874198-B (ZA)
Title: D-fenfluramine for use in the treatment of depression
Inventor: WURTMAN RICHARD J
IPC: A61P25/24
Filed: 1987-06-11
Abstract: D-fenfluramine is administered to a human patient having seasonal depression or other forms of bipolar depression in order to alleviate or cure the depression. The invention provides the respective medicaments.
Patent ZA-882700-B (ZA)
Title: Cannula insertion set with safety retracting needle
Inventor: KULLI JOHN C
IPC: A61M25/06
Filed: 1988-04-18
Abstract: A cannula insertion needle (50) projects from the "forward" end of a hollow handle (10). After use to start a cannula, the needle is released from the end of the handle and its sharp end (52) retracted into the handle, beyond reach. Preferably the handle has an aperture (23) big enough for the needle but too small for fingertips. In one preferred form of the invention, the needle rides in a carrier block (30) that slides inside the handle. Initially the block is secured in the handle against the forward end, with the sharp end of the needle protruding outward through the aperture. A manually releasable latch (40) holds the block in this position. The latch mechanism includes mutually interfering stop elements on the exterior of the block and interior of the handle. After the cannula is in place, the person using the device withdraws the needle from the patient and manually triggers the carrier-block latch (42) by squeezing or rotating one of the stop elements out of engagement with the other. Then a coiled spring (61) drives the block rearward to retract the needle into the handle. At the rear end of the handle a stop (13) halts the carrier block and needle so that they are safely confined within the handle. A standard size tube fitting on the rear of the handle and a hollow needle permit liquid flow to or from the patient through the handle temporarily. <IMAGE>
Patent ZA-886361-B (ZA)
Title: Preparation of olefin/co copolymers
Inventor: GEUZE MAARTEN MARINUS
IPC: C08G67/02
Filed: 1988-08-26
Abstract: Process for the preparation of copolymers, characterized in that a mixture of carbon monoxide with one or more olefinically unsaturated compounds is copolymerized by continuously contacting the mixture in steady state with a solution of a palladium-containing catalyst composition in the presence of liquid diluent in which the copolymers are almost or entirely insoluble, the quotient of the quantity of copolymer formed per hour and the quantity of copolymer in the reactor at any moment being less than 0.2.
Patent ZA-887512-B (ZA)
Title: Apparatus for correctly feeding continuous strips with a shaped side outline to blanking machines
Inventor: CASTIGLIONI GIOVANNE PIETRO
IPC: B21D28/04
Filed: 1988-10-06
Abstract: An apparatus for the correct feeding of continuous strips (11) with a shaped side outline to blanking or pressing machines, such as presses, by means of which the continuous strip, unwinding from a roll, can be feed in a position of perfect trueing under the die of the blanking machine, thanks to the presence of a control and of a continuous correction of the positioning errors caused by stresses, or a non-perfect axiality in the fed strip. The strip (11) is fed by a pair of rolls (24,27) one being motor-driven and operatively connected to sensor elements (23) detecting the change in the shaped side outline of the strip.
Patent ZA-893440-B (ZA)
Title: Expression of hepatitis b s and pres2 proteins in methylotrophic yeasts
Inventor: THILL GREGORY PATRICK
IPC: C12N15/81
Filed: 1989-05-09
Abstract: A process for the enhanced production of antigenic particles consisting essentially of hepatitis B S protein and preS2 protein. Also disclosed are novel DNA molecules and hosts transformed with these molecules.
Patent ZA-898866-B (ZA)
Title: Bone marrow suppressing agents
Inventor: SIMON JAIME
IPC: A61K31/675
Filed: 1989-11-21
Abstract: The invention concerns a method for suppressing bone marrow which comprises administering to a mammal at least one bone marrow suppressing complex of a radionuclide selected from Samarium-153, Gadolinium-159, Holmium-166 and Yttrium-90 and at least one macrocyclic aminophosphonic acid ligand containing the 1,4,7,10-tetraazacyclododecane moiety, or a physiologically acceptable salt thereof. Suitable compositions for use in this method are also provided.
Patent ZA-899396-B (ZA)
Title: Implantable fixing means for extraoral applications
Inventor: KIRSCH AXEL DR
IPC: A61F2/10
Filed: 1989-12-08
Abstract: An implantable fixing device for extraoral applications includes a basic structure implantable in the bone and having either a thread-pressing or a thread-cutting helix, and an implant post being connectible to the basic structure by being inserted in an axial bore therein.
Patent ZA-904804-B (ZA)
Title: Tunnel boring machine
Inventor: FORSBERG JAN H
IPC: E21D9/11
Filed: 1990-06-21
Abstract: Tunnel boring machine comprising a number of swingable arms (11,12,13,14) provided with boring tools (41,42,43,44) for the working of the tunnel wall outside its normal diameter.
Patent ZA-932169-B (ZA)
Title: Sorbing agents
Inventor: COCKETT KEITH ROBERT
IPC: B01J20/08
Filed: 1993-03-26
Abstract: A method of treating a liquid medium to remove from it matter present therein comprises adding to the liquid medium at least one of an at least partially undried sorbing agent (a), a freshly prepared sorbing agent (b) and an in-situ sorbing agent (c). Sorbing agent (a) comprises a hydrotalcite-like material resulting from the preparation thereof in a liquid reaction medium, which preparation allows retention, in the hydrotalcite-like material, of at least 10% of free liquid, based on the weight of the hydrotalcite-like material, including the free liquid, and   (a)1 which sorbing agent is present in an amount, on a dry weight basis, of the sorbing agent, by volume of the liquid medium to be treated, of </=0.035% w/v, or (a)2 the preparation of the hydrotalcite-like material is such as to provide a grain size of the hydrotalcite-like material of </=130 ANGSTROM , as measured in the <001> direction by x-ray diffraction on a subsequently dried material. Sorbing agent (b) comprises a hydrotalcite-like material resulting from the preparation thereof in a liquid reaction medium and present in the reaction medium without substantial removal of the reaction medium.   Sorbing agent (c) comprises a reaction mixture capable of forming, in-situ, in the contaminated liquid medium, a hydrotalcite-like material.
Patent ZA-939193-B (ZA)
Title: Hydroxyamidine derivatives
Inventor: SUH JONGSUK
IPC: A61P17/00
Filed: 1993-12-08
Abstract: The invention relates to the compounds of the formula I <CHEM> wherein the C(=NOH)-NH2 group may be in tautomeric form; and pharmaceutically acceptable salts thereof, in which:  R1 is amino or amino which is mono- or disubstituted X1 and X3, independently of one another, are oxygen (-O-) or sulphur (-S-); and X2 is a divalent aliphatic hydrocarbon radical which may be interrupted by an aromatic radical; The compounds are useful, for example, as selective LTB4 receptor antagonists in the treatment of conditions or syndromes in mammals which are responsive to LTB4 receptor antagonism. They are prepared in a manner known per se.
Patent ZA-946913-B (ZA)
Title: Optical fibre organizer
Inventor: MACKEN LUK JOZEF
IPC: G02B6/00
Filed: 1994-09-08
Abstract: An optical fibre break out device which comprises: 1) means for removably securing the device to an optical fibre organizer; 2) a first passage for retaining a larger fibre tube; and 3) one or more second passages for retaining a plurality of smaller fibre tubes such that fibres can pass between the larger tube and each smaller tube without significant light loss.