Patent SG-11201806161T-A (SG)
Title: Antibodies for il-17c
Inventor: HAAS JAN DOMINIK
IPC: C07K16/24
Filed: 2017-02-17
Abstract: EtH+MOR0.1207 10 mg/kg MC903.MOR03207 10 mg/kg - MC903+DEX 5 mg/kg MC90.3.1,AAENM so mg/kg —• • MC2034MAI301 10 Mg/kg —•- MC9034MAD#1 2 mg/kg - •- MC903+MABIO1 OA mg/kg ............... ......... . . . .... . .... . - ...... . .. ..... ..... ... .... ...... . .......... • 0.23 W O 20 17 / 14083 1 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2017/140831 Al 24 August 2017 (24.08.2017) WIPO I PCT 1111111111111101110111111111110101111101110101111111111111110111011111111111110111111 (51) International Patent Classification: C07K 16/24 (2006.01) A61K 39/00 (2006.01) (21) International Application Number: PCT/EP2017/053592 (22) International Filing Date: 17 February 2017 (17.02.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 16156582.5 19 February 2016 (19.02.2016) EP 16156651.8 22 February 2016 (22.02.2016) EP (71) Applicants: MORPHOSYS AG [DE/DE]; Semmelweis- strasse 7, 82152 Planegg (DE). GALAPAGOS NV [BE/BE]; Generaal De Wittelaan L11 A3, B-2800 Mechelen (BE). (72) Inventors: HAAS, Jan Dominik; Riedener Str. 12, 81475 Mfinchen (DE). KLATTIG, Jurgen; Weinhartstrasse 13c, 82380 PeiBenberg (DE). VANDEGHINSTE, Nick Ernest Rene; Galapagos NV, Generaal De Wittelaan L11/A3, 2800 Mechelen (BE). (74) Agent: SPIELER, Stephan; MORPHOSYS AG, Semmel- weisstrasse 7, 82152 Planegg (DE). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: with international search report (Art. 21(3)) [Continued on next page] (54) Title: ANTIBODIES FOR IL-17C 0.16 Figure 1 (57) : The present invention provides antibodies or antibody fragments binding to human IL-17C. In particular, it relates to antibodies or antibody fragments that have combined beneficial properties and are therefore useful for the treatment of humans hav - ing, for example, atopic dermatitis or psoriasis. WO 2017/140831 Al 1#110HO1101DION0101301011011111110MOEMOVOIMIE — with sequence listing part of description (Rule 5.2(a))