baber/WOPTO huggingface dataset:
Patent EA-007464-B1 (EA)
Title: Metabotropic glutamate receptor antagonists
Inventor: MABIRE DOMINIQUE JEAN-PIERRE
IPC: A61P25/24
Filed: 2001-09-25
Abstract: The present invention concerns compounds of formula (I-A) and (I-B). In a preferable embodiment of the invention, X represents O; Rrepresents Calkyl; cycloCalkyl or (cycloCalkyl)Calkyl, wherein one or more hydrogen atoms in a Calkyl-moiety or in a cycloCalkyl-moiety optionally may be replaced by Calkyloxy, aryl, halo or thienyl; Rrepresents hydrogen; halo; Calkyl or amino; Rand Reach independently represent hydrogen or Calkyl; or Rand Rmay be taken together to form –R-R-, which represents a bivalent radical of formula –Z-CH-CH-CH- or –Z-CH-CH- with Zbeing O or NRwherein Ris Calkyl; and wherein each bivalent radical is optionally substituted with Calkyl; or Rand Rmay be taken together to form a bivalent radical of formula –CH-CH-CH-CH- ; Rrepresents hydrogen; Y represents O; and aryl represents phenyl optionally substituted with halo. The invention also relates to the use of a compound according to the invention as a medicament and in the manufacture of a medicament for treating or preventing glutamate-induced diseases of the central nervous system, as well as formulations comprising such a compound and processes for preparing such a compound.
Patent EA-005443-B1 (EA)
Title: Self-propelled sugar beet-harvester
Inventor: KALVERKAMP KLEMENCE
IPC: A01D17/02
Filed: 2003-10-01
Abstract: A self-propelled sugar beet harvester has a frame comprising a front and rear chassis on which a digging unit is mounted harvesting the product together with adhering earth, a separator unit is also provided after the digging unit where earth, etc. is removed, and a transferring conveyor loading the vegetables flow into a bin. According to the disclosure a digged mixture flow may be transferred on a wide surface having no narrowings along the separating and conveying paths thus the vegetables may flow directly into the bin without any obstacles.
Patent EA-007008-B1 (EA)
Title: Triamide-substituted indoles, benzofuranes and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (mtr) and/or apolipoprotein b (apo b) secretion
Inventor: BERTINATO PETER
IPC: C07D307/85
Filed: 2002-05-24
Abstract: The invention relates to triamide MTP/ApoB inhibitors of the formula 1, wherein R-Rare as defined in the specification, as well as pharmaceutical compositions and uses thereof, and processes for preparing the compounds. The compounds of the invention are useful for the treatment of obesity and lipid disorders.
Patent EA-008530-B1 (EA)
Title: Game machine
Inventor: INAMURA YUKINORI
IPC: G07F17/32
Filed: 2005-04-21
Abstract: For example, in a variable display part 21, when a symbol, "LOBSTER" is stationary displayed in a first stationary display area 211, a symbol, "J" is stationary displayed on a second stationary display area 212, and a symbol, "Q" is stationary displayed on a third stationary display area 213, and if the player touches the first stationary display area 211 with a finger 128, the symbol, "LOBSTER" stationary displayed on the first stationary display area 211 is jumpingly displayed and its jumping sound effect is also output.
Patent EA-007505-B1 (EA)
Title: Process for the preparation of zaleplon
Inventor: RADL STANISLAV
IPC: C07D231/00
Filed: 2003-10-21
Abstract: The invention relates to a process for the preparation of N-[3-(3-cyanopyrazolo[1,5-[alpha]]pyrimidin-7-yl)phenyl)-N-ethylacetamide, having formula I, comprising: reacting N-[3-(3-dimethylamino-acryloyl)-phenyl]-N-ethyl-acetamide with 5-amino- lH-pyrazol-4-carbonitrile in a medium comprising a solution of hydrochloric or hydrobromic acid in a C-Calcohol, or in a C-Caliphatic or cyclic ether, or in a C-Calkoxyalcohol, or in a 5- to 6-membered aromatic heterocyclic solvent, containing 1-2 oxygen atoms, or in mixtures thereof with water.
Patent EA-010010-B1 (EA)
Title: Method for treating glaucoma
Inventor: KASIMOV ELMAR MUSTAFA OGLY
IPC: A61F9/008
Filed: 2005-04-26
Abstract: A method for treating glaucoma relates to medicine, particular to ophthalmology.The claimed method for treating glaucoma laser transscleral contact cyclocoagulation is performed with coagulation of posterior ciliary artery stepping back at 15 mm in 3 and 9 hours. The cyclocoagulation is performed using 0.9-1.0 watt laser radiation, applying 4 coagulates in 12, 6, 3 and 9 hours, after that clockwise, starting from 12 hours apply by 2 intermediate coagulates, and apply by 1 coagulates in between.
Patent EA-011810-B1 (EA)
Title: Sustained release pharmaceutical composition of indapamide
Inventor: KRAMAR ANDREJKA
IPC: A61K9/20
Filed: 2005-01-28
Abstract: Sustained release compositions of indapamide are described which can be prepared by a direct compression mixture and show an improve stability and a high content uniformity.
Patent EA-009510-B1 (EA)
Title: Mat for sport and games
Inventor: HASETH ANDRES
IPC: A63B63/00
Filed: 2004-03-19
Abstract: Mat for sport and games for detecting impact position of a movable object such as a ball. The mat comprises an outer and an inner layer, each with inlays of electrically conductive elements forming a pressure-sensitive switch distributed over the target area. The pressure-sensitive switches communicate with electronic circuits for indicating, processing and presentation of electrical signals when the switches are activated by a ball impact.
Patent EA-011826-B1 (EA)
Title: Purine derivatives as adenosine areceptor agonists and methods of use thereof
Inventor: JAGTAP PRAKASH
IPC: C07H19/12
Filed: 2005-05-25
Abstract: The invention relates to Purine Derivatives, compositions comprising an effective amount of a Purine Derivative; and methods for reducing an animal's rate of metabolism, protecting an animal's heart against myocardial damage during cardioplegia; or for treating or preventing a cardiovascular disease, a neurological disorder, an ischemic condition, a reperfusion injury, obesity, or wasting disease, or diabetes, comprising administering an effective amount of a Purine Derivative to an animal in need thereof.
Patent EA-013739-B1 (EA)
Title: Solid pharmaceutical composition comprising mirtazapine
Inventor: PUNCUN-KOLAR ALESA
IPC: A61K9/16
Filed: 2005-07-12
Abstract: The present invention relates to solid pharmaceutical compositions comprising mirtazapine and a cellulose derivative and in particular to granules and orally-disintegrating tablets.
Patent EA-013666-B1 (EA)
Title: Light wood-based material
Inventor: SCHMIDT MICHAEL
IPC: B27N3/00
Filed: 2007-10-18
Abstract: The invention relates to a light material containing wood having an average density in the region of between 200 to 600 kg/m
Patent EA-017052-B1 (EA)
Title: Sectionalized belt guide for draper belt in an agricultural harvesting machine
Inventor: LOVETT BENJAMIN M
IPC: A01D34/125
Filed: 2009-07-01
Abstract: A cutting platform is proposed for use with an agricultural harvesting machine and includes a plurality of platform sections. At least one platform section includes a cutterbar assembly movable in a localized manner in upwards and downwards directions, an endless belt having a leading edge, a plurality of belt supports mounted to the cutterbar assembly, and a plurality of belt guides. Each belt support is at least partially positioned under the leading edge of the endless belt, and includes at least one upwardly extending clip. Each belt guide partially overlies the leading edge of the endless belt. Each belt guide includes at least one clip hole for receiving a corresponding clip, and a rear surface which is attached to a belt support or the cutterbar assembly.
Patent EA-016975-B1 (EA)
Title: Turbine engine with transverse-flow hydraulic turbines having reduced total lift force
Inventor: ACHARD JEAN-LUC
IPC: F03B17/06
Filed: 2008-10-23
Abstract: The invention relates to a turbine engine (55) that includes at least first and second lift turbine stacks (53A, 53B) with transverse flow. The shafts of adjacent turbines in the first stack are connected by a first coupling device adapted for compensating space misalignments, and the shafts of adjacent turbines in the first stack are connected by a second coupling device adapted for compensating for space misalignments. The turbine engine includes a device (46, 48) for supporting the first and second turbine stacks, which is symmetrical to said plane, and a control device (220A, 220B, 224) adapted for permanently maintaining the symmetry between the first and second turbine stacks relative to the plane, and for maintaining the rotation speeds of the first and second turbine stacks at equal values in opposite rotation directions.
Patent EA-019929-B1 (EA)
Title: 5-β, 14-β-ANDROSTANE DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEINURIA, GLOMERULOSCLEROSIS AND RENAL FAILURE
Inventor: FERRARI PATRIZIA
IPC: A61K31/58
Filed: 2010-03-18
Abstract: Compound of formula (I), wherein the symbol have the meaning reported in the text; for preparing a medicament for the prevention and/or treatment of proteinuria, glomerulosclerosis or renal failure.
Patent EA-022922-B1 (EA)
Title: Method for sequestering carbon dioxide from a top gas fuel
Inventor: METIUS GARY EDWARD
IPC: C01B32/50
Filed: 2010-04-19
Abstract: A method for sequestering carbon dioxide from a waste gas and reusing the waste gas as a recycled gas without emissions concerns, comprising dividing a gas source into a process gas and a waste gas; mixing the process gas with a hydrocarbon and feeding a resulting feed gas into a reformer for reforming the feed gas and forming a reducing gas; and feeding at least a portion of the waste gas into a carbon dioxide scrubber for removing at least some carbon dioxide from the waste gas and forming a carbon dioxide lean gas that is selectively mixed with the reducing gas. Optionally, the method also includes feeding at least a portion of the waste gas into a carbon dioxide scrubber for removing at least some carbon dioxide from the waste gas and forming a fuel gas after the addition of a hydrocarbon that is fed into the reformer. Optionally, the gas source and the reducing gas are associated with a direct reduction process for converting iron oxide to metallic iron in a reduction furnace which uses the reducing gas optionally after some modification and produces the gas source.
Patent EA-022547-B1 (EA)
Title: 6,7-dihydro-5h-benzo[7]annulene derivatives, processes for preparation thereof, pharmaceutical preparations comprising them, and the use thereof for production of medicaments
Inventor: WINTERMANTEL TIM
IPC: C07C323/25
Filed: 2011-06-21
Abstract: The invention relates to selective estrogen receptor modulators (SERMs) and to processes for production thereof, to the use thereof for treatment and/or prophylaxis of disorders, and to the use thereof for production of medicaments for treatment and/or prophylaxis of disorders, more particularly of bleeding disorders, osteoporosis, endometriosis, myomas, hormone-dependent tumors, for hormone replacement therapy and for contraception.
Patent EA-020589-B1 (EA)
Title: Anticancer combination
Inventor: DUMBLE MELISSA
IPC: A61K31/519
Filed: 2010-10-15
Abstract: A novel combination comprising the MEK inhibitor N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide, or a pharmaceutically acceptable salt or solvate thereof, with a B-Raf inhibitor, particularly N-{3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of using such combinations and compositions in the treatment of conditions in which the inhibition of MEK and/or B-Raf is beneficial, eg. cancer.
Patent EA-025969-B1 (EA)
Title: Modular spiral separator element
Inventor: COOKE GRAEME
IPC: B03B5/52
Filed: 2010-11-03
Abstract: The invention provides a spiral separator module 3.010 including at least one trough segment 4.012 having an up stream edge and a downstream edge, each trough segment 4.012 being adapted to interface with at least one other corresponding trough segment 4.012 of a second spiral separator module to form a continuous section of a spiral trough.
Patent EA-026519-B1 (EA)
Title: Undercutting tool and method for creating a blind hole
Inventor: GRUSS CHRISTOPH
IPC: B29C43/42
Filed: 2013-07-12
Abstract: The invention is related to an undercutting tool for creating a blind hole in fluid curable mixtures (1). The undercutting tool has a connecting piece (2) that connects the undercutting tool with a mould (3), a mandrel (4) mounted in the connecting piece (2) and movable along direction of working movement, a cap (6) covering the mandrel (4) in direction of working movement, a casing (7) made of a material reversibly deformable under pressure, the casing (7) embracing the mandrel (4) completely on the outside between the connecting piece (2) and the cap (6). The casing (7) at least one cavity (8) of a preset geometrical shape around the mandrel (4), the geometrical shape of the cavity being set so that the casing (7) is bulged locally under action of pressure along direction of working movement in the area of the cavity (8), which provides formation of a blind hole in mixture (1) surrounding the casing (7), the shape of the hole corresponding to that of the casing in the bulged state.
Patent EA-027641-B1 (EA)
Title: Co-micronisation product comprising ulipristal acetate
Inventor: BATTUNG FLORIAN
IPC: A61P15/18
Filed: 2013-11-07
Abstract: The subject of the present invention is a co-micronization product comprising an active ingredient selected from the group consisting of ulipristal acetate, ulipristal acetate metabolites selected from a certain group of substances and mixtures thereof, and a pharmaceutically acceptable solid surfactant selected from dodecyl sulfate salts and combinations thereof. The invention also relates to a pharmaceutical composition comprising said co-micronization product and to the therapeutic use thereof.
Patent EA-027642-B1 (EA)
Title: Stabilized aqueous water clarifier composition and methods of use thereof
Inventor: HOYLES STEPHEN M
IPC: C08K5/05
Filed: 2013-08-20
Abstract: Oil-water dispersions and emulsions derived from petroleum industry operations are demulsified and clarified using an aqueous water clarifier composition. Formation of such oil-water dispersion and emulsions is inhibited and mitigated using the aqueous water clarifier composition comprising a latex dispersion of an anionic polymer, an alcohol, and a base. The latex dispersion of an anionic polymers comprise an anionic polymer comprising: A) 2-80% by weight of at least one C-Cα,β-ethylenically unsaturated carboxylic acid monomer; B) 15-80% by weight of at least one nonionic, copolymerizable α,β-ethylenically unsaturated monomer; C) 0-50% by weight of one or more of the following monomers: C1) at least one nonionic vinyl surfactant ester; or C2) at least one nonionic, copolymerizable α,β-ethylenically unsaturated monomer having longer polymer chains than monomer B); or C3) at least one nonionic urethane monomer; and, optionally, D) 0-5% by weight of at least one crosslinker.
Patent EA-029963-B1 (EA)
Title: Magnet device comprising an acceleration unit which acts on the translator
Inventor: HEIN JEREMY
IPC: H02P25/02
Filed: 2013-12-23
Abstract: Magnet device comprising at least one stator (1) and a translator (2), which translator (2) can be moved along a translator movement path (3) in a translator movement direction (4) relative to the stator (1), wherein the translator (2) is coupled in at least part regions of the translator movement path (3) to an acceleration unit (5) which, upon coupling of the translator (2) to the acceleration unit (5), causes an acceleration force state which acts on the translator (2), comprising at least one correction force F, which acceleration force state can cause a movement of the translator (2) away from the stator (1), wherein, upon coupling of the translator (2) to the acceleration unit (5) and upon movement of the translator (2) from the stator (1), the sum of the forces which act on the translator (2) in the translator movement direction (4) on account of the magnetism is greater than or equal to zero, with the result that the translator (2) can be released by means of the correction force Ffrom the attractive force which is caused by the stator (1).
Patent EA-030590-B1 (EA)
Title: Use of thiazolo pyrimidinone for the treatment of an inflammatory bowel disease
Inventor: DUTT CHAITANYA
IPC: A61P1/00
Filed: 2014-05-12
Abstract: The present invention relates to a low dose pharmaceutical composition, preferably oral composition comprising a therapeutically effective amount of [(2-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H,5H-10-thia-1,4a-diaza-benzo[a]azulene-3-carbonyl)amino]acetic acid (compound A) in the range of 2.5 to 60 mg. The present invention also relates to a method of treating an inflammatory bowel disease in mammals by administrating said low dose pharmaceutical composition. Further, the present invention relates to the use of the compound A for the preparation of the low dose pharmaceutical composition for the treatment of an inflammatory bowel disease in mammals.
Patent EA-028775-B1 (EA)
Title: 4-AMINO-6-PHENYL-6,7-DIHYDRO[1,2,3]TRIAZOLO[1,5-a]PYRAZINE DERIVATIVES AS INHIBITORS OF BETA-SECRETASE (BACE)
Inventor: OEHLRICH DANIEL
IPC: A61K31/4985
Filed: 2014-06-12
Abstract: The present invention relates to novel 6,7-dihydro[1,2,3]triazolo[1,5-a]pyrazin-6-yl derivatives of formula (I)wherein R-Rare defined in the claims, as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, in particular BACE1 and/or BACE2 (wherein BACE1 is also known as Asp2 or memapsin 2 and BACE2 is also known as Asp1, memapsin 1 or DRAP). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease, dementia of the Alzheimer's type, dementia associated with beta-amyloid, age-related macular degeneration, type 2 diabetes and other metabolic disorders.
Patent EA-029196-B1 (EA)
Title: Prestressed reinforced concrete bar production line
Inventor: BEREGOVOJ ALEKSEY VALERIEVICH
IPC: B28B23/02
Filed: 2015-12-18
Abstract: The invention is related to the field of railway transport and to the field of production of reinforced concrete structures, and can be used for manufacture of reinforced concrete under-rail bases, in particular, reinforced concrete sleepers and switch bars. The technical result is higher productivity of bar production; ensuring identical strength properties of bars; better quality and appearance of final products; higher bar loading forces due to an increase in prestress forces; and higher reliability and durability of a rail track including such bars. Said result is attained by provision of a prestressed reinforced concrete bar production line comprising a forming bed (1) with side walls and end walls, and fixtures (5) of reinforcing rods (6), wherein the line in accordance with the invention is provided with separating diaphragms (2) arranged along the longitudinal axis of the forming bed (1) to form a plurality of cells, each cell being intended for an individual bar, the forming bed (1) is mounted on support posts (3), and fixtures (5) of reinforcing rods (6) are fixed on the side of end walls of the forming bed (1). The separating diaphragm (2) is composed of wedge-shape elements and inserts. The line is provided with electromagnets (9) fixed in supports (8). The line may include at least two forming beds (1) joined to each other by side walls. The fixtures (5) of reinforcing rods (6) are made as collet clamps, and the forming bed is provided with a heat-insulation coating.
Patent EA-037586-B1 (EA)
Title: Translucent structure with comprehensive blow-through and leakage protection
Inventor: VILMONT ANDREY VALENTINOVICH
IPC: E06B3/26
Filed: 2016-06-14
Abstract: The invention relates to building structures, in particular to building structures made of metal, primarily to frame structures with special devices for insulation (comprehensive blow-through and leakage protection) and can be used for erection of translucent structures in buildings and structures of various purposes. A translucent structure is proposed, which is made in the form of a frame structure, where glazing elements (3) are secured by means of beads (4) fixed from the inside. The structure contains many seals (5, 6, 8) placed between the elements (1, 2) of the frame structure and the glazing elements (3). Support pads (7) are provided between the end faces of the glazing elements (3) and the frame structure elements (2). In the proposed translucent structure, a plurality of seals placed in the installation area of the bead (4) between the lower end of the glazing element (3) and the corresponding horizontal element (2) of the frame structure are made in the form of one common seal (8) the length of which corresponds to the length of the specified element (2) of frame structure. In this case, the common seal (8) is placed between the specified element (2) of frame structure and the support pads (7) installed on it, and along its entire length from the side of the glazing bead installation, it has with a longitudinal section (9) located outside the support pads (7). The width and shape of the longitudinal section (9) are selected with the possibility of hermetic adherence to the vertical leg (10) of the bead (4) along the entire length of the common seal (8).
Patent EA-032184-B1 (EA)
Title: Device and method for anchoring an overhanging element to a construction
Inventor: CATTEAU MICHEL
IPC: E04B1/00
Filed: 2015-03-25
Abstract: Provided is a device for anchoring an overhanging element (B) to a construction (A), which device comprises two coupling parts (2, 3), one coupling part of which is suitable to be connected to the overhanging element (B) whereas the other one is suitable to be connected to the construction (A), and whereby the coupling parts (2, 3) are provided with mechanical coupling means (6, 29) and whereby at least one of the coupling parts (2, 3) comprises a freely protruding element (4) whose maximum length is larger than 10 cm.
Patent EA-030010-B1 (EA)
Title: Heat exchanger
Inventor: FUJITA YASUHIRO
IPC: F28F9/02
Filed: 2015-03-16
Abstract: This heat exchanger (100) is equipped with a core section (1), a header section (2), and an intermediate member (3), the radius of curvature of corner sections (31a-31d) of the intermediate member (3) being configured so as to be less than the radius of curvature at the header section side.
Patent EA-032400-B1 (EA)
Title: Disposable apparatus for circumcision
Inventor: SHANG JIANZHONG
IPC: A61B17/326
Filed: 2012-10-26
Abstract: A disposable apparatus for circumcision comprises a fixing device containing an external wall, wherein the external wall is provided with an opening; a flange going along the internal surface of the external wall, wherein the flange contains the first mating part of the flange and the second mating part of the flange both being mated with each other when the fixing device is in closed position, wherein the flange is provided additionally with an internal circular edge of the flange; a buffering ring for positioning opposite the flange; means for retaining the fixing device in a closed position; and a ring for the penis head located inside the buffering ring and fixing device. The buffering ring comprises a groove going along the internal circular edge of the buffering ring for housing the internal circular edge of the arm or the buffering ring comprises a groove going along the internal circular edge of the buffering ring and the flange is positioned wholly inside the said groove.