baber/WOPTO huggingface dataset:
Patent CA-2514642-C (CA)
Title: Therapie combinee destinee au traitement de troubles associes a une carence proteique
Inventor: FAN JIAN-QIANG
IPC: C12N9/40
Filed: 2004-02-02
Granted: 2015-03-17
Abstract: L'invention concerne des méthodes permettant d'améliorer une thérapie par remplacement de protéines par combinaison d'une thérapie par remplacement de protéines à des chaperons spécifiques de site actif (ASSC) afin d'améliorer la stabilité et l'efficacité de la protéine administrée. L'invention concerne en outre des compositions comprenant la protéine purifiée et un ASSC, et des méthodes de traitement consistant à administrer ces compositions.
Patent CA-2516399-C (CA)
Inventor: MAURER BARRY JAMES
IPC: A61K31/739
Filed: 2004-02-19
Granted: 2013-05-14
Abstract: The present invention provides stable aqueous solutions consisting essentially of: (a) a sphingolipid; (b) lactic acid; and (c) optionally a stabilizing agent; wherein the solution has a molar ratio of lactic acid to sphingolipid of 1:1 to 10:1. The present invention further provides an emulsion formulation consisting essentially of: (a) lactic acid; (b) a sphingolipid, wherein the sphingolipid is present in an amount of about .1 to about 30 mg/ml of emulsion; (b) optionally an isotonic agent; and (c) a phospholipid present in an amount of about 0.2 to about 200 mg/ml of emulsion. Methods of making and using the compositions are also provided.
Patent CA-2516570-C (CA)
Inventor: PIERRY ANTHONY T
IPC: G01N21/35
Filed: 2004-02-19
Granted: 2012-05-08
Abstract: A method and apparatus for interfacing a plurality of gas measurement systems (8, 28, 60), including a mainstream and a sidestream gas measurement system, to a host system (74) via an interface unit (64). The present invention also pertains to a sidestream gas measurement system (80) that outputs signals emulating the signals output by a mainstream gas measurement system or portion thereof, so that the sidestream gas measurement system can seamlessly communicate with a host system configured to communicate only a mainstream gas measurement system or a portion thereof.
Patent CA-2518837-C (CA)
Title: Cementitious compositions containing interground cement clinker and zeolite
Inventor: LUKE KAREN
IPC: C09K8/467
Filed: 2005-09-12
Granted: 2009-10-27
Abstract: Methods and compositions for wellbore treating fluids, especially cementitious compositions that include interground cement clinker and zeolite, with and without gypsum.
Patent CA-2523862-C (CA)
Title: Apparatus for radially expanding and plastically deforming a tubular member
Inventor: TREECE HAROLD
IPC: E21B29/00
Filed: 2004-04-15
Granted: 2009-06-23
Abstract: An apparatus for radially expanding and plastically deforming a tubular (100).
Patent CA-2533683-C (CA)
Title: Magnetic separation apparatus and methods
Inventor: TERSTAPPEN LEON W M M
IPC: G01N1/40
Filed: 1999-11-30
Granted: 2010-01-12
Abstract: Apparatuses and methods for separating, immobilizing, and quantifying biological substances from within a fluid medium. Biological substances are observed by emptying a vessel (6) having a chamber therein, the vessel comprising a transparent collection wall (5). A high internal gradient magnetic capture structure may be on the transparent collection wall (5), magnets (3) create an externally-applied force for transporting magnetically responsive material toward the transparent collection wall (5). The magnetic capture structure comprises a plurality of ferromagnetic members and has a uniform or non-nonuniform spacing between adjacent members. There may be electrical conductor means supported on the transparent collection wall (5) for enabling electrical manipulation of the biological substances. The chamber has one compartment or a plurality of compartments with differing heights. The chamber may include a porous wall. The invention is also useful in conducting quantitative analysis and sample preparation in conjunction with automated cell enumeration techniques.
Patent CA-2539439-C (CA)
Inventor: MOORE MICHAEL
IPC: C07K14/47
Filed: 2004-09-17
Granted: 2012-10-23
Abstract: Disclosed herein are methods and compositions for modulation of gene expression, with single-gene specificity, in a human sized genome.
Patent CA-2542552-C (CA)
Title: Method and apparatus for coal gasifier
Inventor: SPROUSE KENNETH M
IPC: C10J3/84
Filed: 2006-04-10
Granted: 2013-11-26
Abstract: A method and apparatus for efficiently forming a gaseous material from a solid starting material. The produced gaseous material includes a CGE HHV having a high percentage of an original HHV of the starting material. The gaseous product may be used to form a plurality of materials for various purposes.
Patent CA-2547098-C (CA)
Title: Cannulated fastener system
Inventor: CICCONE PAUL
IPC: A61B17/56
Filed: 2004-11-24
Granted: 2012-10-09
Abstract: A cannulated fastener system is provided for orthopedic applications that include attaching bone plates to bone. The bone fastener has a cannulation with an inner shape. One or more screwdrivers is provided with a shaft having a shape that matches the cannulation of the fastener to rotationally fix the fastener to the screwdriver. In addition, the screwdrivers have a cutting blade that begins the drilling of a hole for the bone fastener. The screwdrivers may either be for use with a single fastener or have multiple fasteners loaded within a retaining sleeve for automatic or controlled dispensing.
Patent CA-2547582-C (CA)
Inventor: SCHADE CHRISTOPHER T
IPC: C22C33/02
Filed: 2004-10-27
Granted: 2012-02-07
Abstract: The metallurgical powder composition suspensions of the present invention include a magnetic powder having an outer oxide layer suspended in a carrier fluid. Magnetic powders include iron-based powders, such as for example, powders of iron pre-alloyed with other elements. Alloying materials include columbium, silicon, calcium, manganese, magnesium, carbon, boron, aluminum, titanium, molybdenum, chromium, copper, nickel, gold, vanadium, phosphorus, or combinations thereof Carrier fluids include silicon-based fluids and/or oils, such as hydrocarbon oils. The outer oxide layer includes alloy materials that are reacted/complexed with oxygen. Magnetic powders exhibit low rates of oxidation over a broad temperature range. Articles incorporating metallurgical powder composition suspensions include dampeners having a chamber, a piston that reciprocates in the chamber, and a source of magnetism operatively connected to the chamber. The source of magnetism, when activated, produces a magnetic field that changes the apparent viscosity of the metallurgical powder composition suspension.
Patent CA-2548095-C (CA)
Title: Blood filter assembly having multiple filtration regions
Inventor: BLICKHAN BRYAN J
IPC: A61M1/34
Filed: 2004-12-07
Granted: 2013-02-12
Abstract: A filtration medium (14) is sealed within a housing (52, 54). The filtration medium (14) is sized and configured to define multiple filtration regions (28, 30) within the housing (52, 54), through which independent, though concurrent, blood filtration can occur. Each filtration region (28, 30) is served by its own inlet path, which conveys blood into the filtration region (28, 30). The filtration medium (14) in each region (28, 30) passes the blood to remove at least one undesired component, such as leukocytes. After filtration, the multiple regions (28, 30) convey the blood into a single, centrally located manifold (36). A single outlet (18) communicates with the manifold (36).
Patent CA-2552760-C (CA)
Inventor: TOMA PETER
IPC: B01D53/26
Filed: 2005-01-26
Granted: 2009-09-15
Abstract: A method and apparatus for separating liquid droplets from a gas stream. The method includes the steps of conditioning the gas stream which contains the droplets so that the gas stream exhibits substantially turbulent flow, passing the gas stream generally axially through a flowpath so that the gas stream is in communication with a collector surface, collecting the droplets on the collector surface, and draining the collector surface to remove the collected droplets from the collector surface. The apparatus includes a flowpath, a collector surface for collecting the droplets, a flow conditioner for conditioning the gas stream, and a drainage mechanism for draining the collected droplets from the collector surface.
Patent CA-2562873-C (CA)
Inventor: AHMAD-TAYLOR TY O
IPC: H04N21/472
Filed: 2005-03-10
Granted: 2014-04-29
Abstract: L'invention concerne un procédé et un système permettant de fournir électroniquement un guide de listage de télévision. Le guide de listage comprend un certain nombre de canaux se croisant avec un certain nombre de tranches horaires pour afficher un réseau de cellules qui peuvent être sélectionnées afin de visualiser un programme correspondant avec la cellule. Le guide permet à un téléspectateur d'associer facilement une cellule sélectionnée avec ses données de programme.
Patent CA-2570042-C (CA)
Inventor: BRUMMERHOP HARM
IPC: A61P3/10
Filed: 2005-06-03
Granted: 2013-01-15
Abstract: The invention relates to substituted fluoroglycoside derivatives of pyrazoles of formula (I), in which the radicals have the indicated meanings, to the physiologically compatible salts thereof, and to a method for the production thereof. The compounds are suited for as, e.g. antidiabetics.
Patent CA-2573027-C (CA)
Title: Scratch resistant polyolefins
Inventor: SHARMA ASHUTOSH H
IPC: C08K5/20
Filed: 2005-06-27
Granted: 2013-04-02
Abstract: Polyolefin substrates, for example polypropylene, polyethylene or thermoplastic olefin molded parts, are made scratch resistant by the incorporation therein of an additive combination of a maleated alpha-olefin functionalized with a long chain alcohol or long chain amine and a primary or secondary fatty acid amide. The present polyolefins exhibit good weatherability, scratch resistance, good processability, good mechanical strength, good gloss retention and are non-sticky. The functionalized maleated alpha-olefin is for example the ester or half ester of maleated C18-C26 alpha-olefin with tallow fatty alcohol. The fatty acid amide is for example oleyl palmitamide or stearyl erucamide.
Patent CA-2575223-C (CA)
Inventor: GUEVEL ALYX CAROLINE
IPC: A61K31/437
Filed: 2005-06-28
Granted: 2013-08-06
Abstract: The present invention relates to 7-azaindole-based compounds, to processes for the preparation thereof, to pharmaceutical compositions com~prising them, and to the use thereof in the preparation of medicaments that are useful as inhibitors of MTP and of ApoB secretion.
Patent CA-2579289-C (CA)
Inventor: KNOBLE JESSE
IPC: B60G13/00
Filed: 2005-09-02
Granted: 2013-02-05
Abstract: A mounting apparatus for use within a suspension system having a frame member, a control arm, and an elongated suspension member extending between the frame member and the control arm is disclosed. The mounting apparatus includes a cup, a seal, a resilient element, and a fastener. The cup includes an end that is at least partially closed, a side wall, and an open end. The seal is disposed within the cup and is configured to be coupled to the elongated suspension member. The resilient element is at least partially disposed within the cup and is substantially encapsulated by the cup and the seal. The fastener is configured to couple the cup, the seal, and the resilient element between the elongated suspension member and one of the frame member and the control arm.
Patent CA-2586837-C (CA)
Inventor: BUCKNELL PAUL
IPC: H04L12/54
Filed: 2005-11-04
Granted: 2015-01-06
Abstract: Data packets having different assigned priorities are multiplexed by operating a queue for each different priority of data packet and assembling groups (80) of the data packets for transmission. Each group has two portions. A first portion (90) of the group is populated with data packets selected from one or more of the queues according to a first rule and a second portion (95) of the group is populated with data packets selected from one or more of the queues according to a second rule. Preferably the first portion contains data packets having the highest priority, and the second portion contains a selection of the data packets having a lower a priority. Selection of data packets for the second portion may depend on criteria such as delay experienced and queue length. The size of the first and second portions may be adapted according to delay experienced and queue length.
Patent CA-2593973-C (CA)
Title: Hand triggered tissue sealant spray apparatus and system
Inventor: REDL HEINZ
IPC: B67D7/70
Filed: 2006-01-12
Granted: 2014-11-18
Abstract: The present invention is generally directed to various structures for applying a sealant to a work surface. In one aspect of the invention, a sealant applicator assembly is provided for use with an apparatus of the type having an elongated body (2) defining an interior bore and having a piston (48, 50) movably positioned in the bore and a pusher member (53, 54) operatively associated with the piston. The assembly comprises a spray adaptor (12) adapted to communicate with the bore of the body and defining a distal outlet.  A first gas passageway (8) is cooperatively associated with the distal outlet and configured to direct gas to create a spray discharge of the sealant. An actuating member (86) is adapted to be cooperative associated with a pusher member to eject sealant through the distal outlet and is operative to simultaneously actuate a supply of gas to the first gas passageway for creating a spray discharge of sealant.
Patent CA-2595025-C (CA)
Title: Compositions moussantes a haute teneur en alcool avec des agents tensioactifs a base de silicone
Inventor: FERNANDEZ DE CASTRO MARIA TERESA
IPC: C11D17/00
Filed: 2006-03-07
Granted: 2011-01-25
Abstract: La présente invention concerne une composition liquide ayant une « haute teneur en alcool inférieur » (> 40 % en volume d'un alcool en C1-C4) capable d~être distribuée sous la forme d~une mousse stable en utilisant des dispositifs de distribution de mousse sans gaz propulseur à partir de récipients non pressurisés. Les compositions liquides comprennent un alcool en C1-C4 (> 40 % en volume), un agent tensioactif à base de silicone constituant au moins 0,001 % en poids destiné à préparer une composition moussante, de 0 à 10 % en volume de composants mineurs supplémentaires ajoutés de façon à obtenir la performance souhaitée (une composition moussante), le reste étant de l'eau purifiée. Les compositions peuvent comprendre des émollients émulsifiants et des hydratants, des agents tensioactifs secondaires, des stabilisateurs de mousse, des parfums, des agents antimicrobiens, d'autres types de substances médicinales et des ingrédients analogues ou des additifs ou des combinaisons de ceux-ci généralement ajoutés à des gels ou mousses alcooliques, des compositions d~aérosol ou à des articles de toilette, des produits de beauté, des produits pharmaceutiques et analogues.
Patent CA-2598536-C (CA)
Title: Oxyindole derivatives as 5ht4 receptor agonists
Inventor: KAWAMURA KIYOSHI
IPC: C07D401/12
Filed: 2006-02-10
Granted: 2011-04-05
Abstract: This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, R1 , R2, R3 , R4 and R5 are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by 5-HT4 agonisitic activity such as, but not limited to, as gastroesophageal reflux disease, gastrointestinal disease, gastric motility disorder, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome (IBS), constipation, dyspepsia, esophagitis, gastroesophageral disease, nausea, central nervous system disease, Alzheimer's disease, cognitive disorder, emesis, migraine, neurological disease, pain, cardiovascular disorders, cardiac failure, heart arrhythmia, diabetes or apnea syndrome.
Patent CA-2605452-C (CA)
Title: Techniques de transitique pour systeme d'animation graphique informatique
Inventor: HERMAN DANIEL LAWRENCE
IPC: G06F7/00
Filed: 2006-04-18
Granted: 2016-07-26
Abstract: L'invention concerne des techniques de transitique pour un système d'animation graphique informatique (CG). Dans quelques modes de réalisation, des systèmes et des procédés servent à représenter une composition de scène et à exécuter des calculs sous-jacents à l'intérieur d'un graphique d'expression unifié et généralisé comportant des cycles. Elle concerne des mécanismes naturels de contrôle de niveau de détail, de mise en antémémoire adaptative, de recours minimum à de nouveaux calculs, d'évaluation paresseuse, de calcul prédictif et de raffinement progressif. Ces modes de réalisation fournissent des garanties en temps réel de fréquences de trames graphiques minima et d'options automatiques de support entre la qualité du rendu, sa précision et sa vitesse. Elle supporte également de nouveaux paradigmes de flux de travail, y compris l'animation stratifiée et la manipulation de la trajectoire de mouvement de corps articulés.
Patent CA-2613143-C (CA)
Inventor: SCHWOERER ARTUR
IPC: E04G11/28
Filed: 2006-06-20
Granted: 2010-12-07
Abstract: A climbing cylinder (10) of self-climbing formwork in the building area is provided such that it can move climbing rails (22) along a wall (12). At one end the climbing cylinder (10) has a fixing for an anchor point of the wall and at the other end a catch (30) is provided on the climbing cylinder, which can be brought into engagement with the climbing rail such that it bears the climbing rail (10) on the one hand and can displace it on the other hand.  The climbing cylinder (10) can be fixed at an anchor point of the building or on a climbing shoe (18).
Patent CA-2619660-C (CA)
Title: Derives imidazolo condenses utilises pour inhiber l'aldosterone synthase et l'aromatase
Inventor: KSANDER GARY MICHAEL
IPC: A61P35/00
Filed: 2006-08-23
Granted: 2015-01-06
Abstract: Cette invention concerne un composé représenté par la formule (I). Ce composé est un inhibiteur de l'aldostérone synthase et de l'aromatase et peut par conséquent être utilisé dans le traitement d'un trouble ou d'une maladie induit par l'aldostérone synthase ou l'aromatase. Ainsi, le composé représenté par la formule (I) peut être utilisé pour traiter l'hypokaliémie, l'hypertension, l'insuffisance cardiaque congestive, la fibrillation auriculaire, l'insuffisance rénale, en particulier l'insuffisance rénale chronique, la resténose, l'athérosclérose, le syndrome X, l'obésité, la néphropathie, le post-infarctus myocardique, les coronaropathies, l'inflammation, la surproduction de collagène, la fibrose telle que la fibrose cardiaque ou myocardique et le remodelage suite à une hypertension et à un dysfonctionnement endothélial, la gynécomastie, l'ostéoporose, le cancer de la prostate, l'endométriose, les fibroïdes utérins, la ménométrorragie, l'hyperplasie endométriale, la maladie des ovaires polykystiques, l'infertilité, la maladie mammaire fibrokystique, le cancer du sein et la mastopathie fibrokystique. Cette invention concerne enfin une composition pharmaceutique.
Patent CA-2620209-C (CA)
Title: Article en acier maraging et son procede de fabrication
Inventor: MUHA JOSEPH F
IPC: C22C38/52
Filed: 2006-08-10
Granted: 2015-05-05
Abstract: La présente invention concerne un article en alliage d~acier maraging de très haute densité produit en métallurgie des poudres constitué d~une poudre d~un pré-alliage destiné à un usage comme outil pour des applications à hautes températures. La présente invention concerne l~article dans les conditions de production ayant une dureté HRC inférieure à 40 pour conférer une certaine usinabilité et ensuite l'article après traitement thermique de maraging ayant une dureté HRC supérieure à 45. Un procédé de production de cet article comprend le compactage de la poudre de pré-alliage pour produire un article de très haute densité ayant une dureté HRC inférieure à 40 et ensuite le traitement thermique de maraging pour donner une dureté HRC supérieure à 45.
Patent CA-2622028-C (CA)
Inventor: RASHBAUM RALPH
IPC: A61F2/44
Filed: 2006-09-23
Granted: 2014-04-01
Abstract: The invention relates to an intervertebral disc prosthesis comprising at least two plates (1, 2), namely first (1) and second (2) plates, articulated about each other by means of a curved surface (11, 31), namely articulation, of at least one of the plates, each of the plates (1, 2) comprising a surface (14, 24) known as a contact surface, intended to be in contact with a vertebral plate of one of the vertebrae between which the prosthesis is intended to be inserted, this contact surface for each of the plates comprising a geometrical centre (G1, G2) at equal distance from at least two diametrically opposite points located on the periphery of the plate (1, 2), characterised in that the geometric centres (G1, G2) of the plates (1, 2) are not vertically aligned, this off-setting (D) of the geometrical centres (G1, G2) of the plates engendering an off-setting of the edges of the plates (1, 2) in at least one direction perpendicular to the vertical axis of the spinal column.
Patent CA-2623683-C (CA)
Title: Passenger dorsal support
Inventor: DANEAULT LOUIS-PHILIPPE
IPC: B60N2/64
Filed: 2008-02-28
Granted: 2012-07-03
Abstract: A dorsal support for supporting a passenger in a generally upright standing position while travelling in a public transportation vehicle is disclosed. The dorsal support comprises a body having a front surface extending uninterrupted upwardly from a base portion fastened to a floor surface, the front surface of the body including a planar lower portion preventing access behind the dorsal support from in front thereof and an upper portion which is integral with the lower portion and extends upwardly therefrom. The upper portion is rearwardly inclined and defines a passenger receiving area thereon for supporting at least a portion of the passenger's back such as to support the passenger in a generally upright standing position when leaning against the dorsal support.
Patent CA-2624088-C (CA)
Title: Formulation de medicaments a petites molecules a liberation prolongee
Inventor: LUK ANDREW S
IPC: A61K45/00
Filed: 2006-09-28
Granted: 2016-03-08
Abstract: L'invention concerne une formulation à injection retard comprenant un polymère biocompatible, un solvant organique combiné au polymère biocompatible pour former un gel visqueux, et un médicament à petites molécules incorporé dans le gel visqueux de façon que la formulation présente un profil de libération in vivo avec un rapport Cmax à Cmin inférieur à 200 et un décalage inférieur à 0,2.
Patent CA-2624283-C (CA)
Title: Procede et systeme permettant des communications asynchrones sur internet
Inventor: CLARKE DAVID JAMES
IPC: H04L29/06
Filed: 2005-09-29
Granted: 2009-12-22
Abstract: L'invention porte sur un système de communications pouvant comporter un dispositif client permettant à des tâches de traitement de courriels et à un serveur mandataire de communiquer de manière asynchrone sur Internet avec le dispositif client pour traiter les tâches de traitement de courriels. Le dispositif client peut poster une tâche donnée de traitement de courriels au serveur mandataire au moyen d'un seul identificateur de tâche (ID), et le serveur mandataire peut ensuite poster au dispositif client les résultats de la tâche également au moyen de ce seul identificateur de tâche (ID). En outre, le dispositif client pourra poster de préférence au moins une tâche de traitement de courriels au serveur mandataire via Internet à un moment se situant entre l'envoi de la tâche donnée de traitement de courriels et la réception des résultats correspondants.
Patent CA-2625096-C (CA)
Inventor: CALVO SALVE PILAR
IPC: A61K47/26
Filed: 2006-10-30
Granted: 2015-11-24
Abstract: Provided are formulations comprising jorumycin, renieramycin, safracin and saframycin related compounds of general formula (I), (see formula I) methods of preparing the same, articles of manufacture and kits with such formulations, and methods of treating proliferative diseases with the same formulations.