baber/WOPTO huggingface dataset:
Patent CA-2201302-A1 (CA)
Title: An attenuated vaccination and gene-transfer virus, a method to make the virus and a pharmaceutical composition comprising the virus
Inventor: MENKE ANNETTE
IPC: C12N15/86
Filed: 1995-09-18
Abstract: RNA polymerase I transcription in vivo in transiently DNA-transfected cells has been used for expression of influenza vRNA molecules coding for chloramphenicol acetyltransferase (CAT) in anti-sense orientation. Influenza virus superinfection served to provide viral RNA polymerase and other proteins for transcriptional conversion of minus-strand vRNA into plus-strand viral mRNA molecules expressing CAT activity. This system has been used for an analysis via nucleotide exchanges as well as deletions and insertions of both terminal segments of the vRNA sequence which cooperatively constitute the vRNA promoter structure. Several mutants with greatly enhanced expression rates over wild-type levels have been constructed, which also can be packaged and serially passaged into progeny virus. The data obtained for the mutations in various promoter elements support a model of consecutive, doublestrand vRNA promoter structures in binding of viral polymerase and initiation of RNA synthesis. Preparations of attenuated influenza virus for vaccination purposes include a single recombinant segment with promoter up mutation(s) for overexpression of an own or foreign gene product, which at the same time because of its over-replication serves to decrease the number of helper virus RNP segments. The same viruses further have been passaged through a step of ribozyme cleavage acting at one of the helper viral segments, which will delete this vital function and structure with high rates from the virus progeny. The resulting attenuated viruses will interact with their target cells in only one round of abortive infection, and are unable to produce viral progeny.
Patent CA-2201924-A1 (CA)
Inventor: DIGENIS GEORGE A
IPC: A61K9/52
Filed: 1994-10-06
Abstract: L'invention concerne une gélule (10) réalisée en un produit tel que la gélatine, l'amidon ou un polymère hydrophile. Cette gélule constitue un système d'administration où la composante active du point de vue pharmacologique est placée dans trois compartiments séparés ou davantage. Lorsque la gélule comprend trois compartiments, le compartiment externe (12) est constitué par une couche externe formant un revêtement sur la gélule et contenant un médicament et des excipients. Cette couche permet une libération rapide du médicament. Le compartiment intermédiaire (11) contient une poudre constituée d'un médicament et d'excipients, qui représente la partie du système assurant une libération à une vitesse intermédiaire. Le compartiment le plus interne contient le ou les ingrédients actifs sous une forme multiparticulaire, par exemple de petits granulés (14), et il représente la partie du système assurant une libération lente.
Patent CA-2202759-A1 (CA)
Inventor: MARKANTES CHARLES T
IPC: G07D7/128
Filed: 1995-10-19
Abstract: A viewing device (19) for use by an observer (63) to ascertain the authenticity of an instrument of value (16) having an image (17) formed from an optically variable device (18). The viewing device (19) includes a frame structure (23) which permits viewing of the image (17) in a fixed spatial orientation and a reflector (61) carried by the frame structure (23) for permitting the observer (63) to see simultaneously the image (17) in first and second colors without movement of the observer (63), the viewing device (19) or the image (17).
Patent CA-2203075-A1 (CA)
Inventor: GOGLIO LUIGI
IPC: B65D47/14
Filed: 1997-04-18
Abstract: An anti-spill device for liquid containers, in particular for dense or viscous liquids, consisting of a cup-shaped element (11) or under-cap, of elastic material, inserted in the spout (3) of the container and forming a liquid seal, withstanding a pressure at least equal to the pressure exerted by the weight of the liquid held in the container (1) on said cup-shaped element (11), so that the container can be overturned without there being any separation of the under-cap (11), which occurs only following an increase in the pressure inside the container, caused for example by squeezing the side wall (14) thereof, the under-cap (11) being connected, by means of a rod-shaped extension (20) to radial elastic fins (22), such as to avoid complete detachment of the anti-spill device from the container.
Patent CA-2203293-A1 (CA)
Inventor: GUERET JEAN LOUIS H
IPC: A45D40/26
Filed: 1996-08-13
Abstract: L'invention concerne un ensemble de conditionnement (1) transportable et éventuellement rechargeable pour produit, liquide à pâteux, en particulier pour mascara, comportant un applicateur (3) et un réservoir (5) muni d'au moins un essoreur (19). L'applicateur (3) comporte un manche (7) et au moins une touffe (12) de poils implantée parallèlement au plan moyen de ce manche, ces poils (11) étant de forme et de longueur particulières et aptes à charger du produit, en particulier du mascara, sur des fibres kératiniques, et en particulier des cils. Le réservoir (5) a une longueur sensiblement égale à celle des poils de l'applicateur.
Patent CA-2204063-A1 (CA)
Title: Machine for automatically manufacturing puzzle-lock compression rings
Inventor: OETIKER HANS
IPC: B21D39/03
Filed: 1997-04-30
Abstract: A method and machine for manufacturing compression rings in which flat band material is fed to a stamping station from a feed station, a blank is stamped out with a mechanical connection having male and female configurations at opposite ends, the blank is then fed to a deformation machine where it is displaced into the several axial positions of the machine in which, in a first position, the blank is predeformed into configuration permitting closing of the mechanical connection in a second position in which the blank is also deformed into its circular configuration. Preferably the thus-deformed and closed compression ring is then subjected to a swaging action in a third position before it is ejected out of the machine.
Patent CA-2208588-A1 (CA)
Inventor: PLANCHE JEAN-PASCAL
IPC: C08L57/00
Filed: 1996-10-16
Abstract: L'élastomère fonctionnalisé (EF) est formé d'un substrat élastomère, ayant une masse moléculaire moyenne en poids (a) entre 10000 et 600000 daltons et un indice de polydispersité inférieur à 5, sur lequel sont greffées, en quantité allant de 0,1 % à 10 % en poids du substrat, des séquences (b) où R1 est un radical hydrocarboné (x+z+1)-valent en C1 à C12, X représente H ou un radical hydrocarboné monovalent R en C1 à C12, z est égal à zéro ou 1 et x est un nombre entier allant de 1 à 3, avec x+z 3, la masse moléculaire moyenne en poids (Mw) dudit EF étant telle que le rapport (c) soit inférieur à 20 %. On produit des compositions bitume/EF utilisables pour la réalisation de revêtements en incorporant ledit EF à une composante bitumineuse.
Patent CA-2210217-A1 (CA)
Title: Composite panel
Inventor: MULLER PETER
IPC: E04C2/36
Filed: 1997-07-11
Abstract: A composite panel comprising a core (12) and at least one outer sheet (14) which is adhesively bonded to the core is such that the composite panel (10) is shape-formed creating at least one radius of bending (24b) in the outer layer (14). The core (12) exhibits a cellular structure and is bonded to the outer layer (14) at least by one visco-elastic adhesive layer (16) applied over a large area. The combination of the honeycomb structure of the core and the adhesive layer with the mentioned properties attaching the core to the outer sheet leads to a composite panel that may be shaped quickly and at favourable cost, without the outer layers being damaged or the strength being significantly reduced. As a result of the large area visco-elastic bonding a higher resistance to delamination, debonding due to vibration, corrosion and moisture is achieved.
Patent CA-2212113-A1 (CA)
Title: Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
Inventor: KABALNOV ALEXEY
IPC: A61K49/22
Filed: 1996-02-15
Abstract: A gas emulsion forming composition comprising a dry, hollow, particulate, approximately microspherical material permeated with a gas or gas mixture, which upon dissolution in aqueous liquid forms a gas emulsion comprising a plurality of bubbles surrounded by a layer of at least a first and a second surfactant, wherein the first surfactant consists essentially of a phospholipid or mixture of phospholipids having at least one acyl chain which comprises at least 10 carbon atoms, and comprising at least about 5 % w/w of total surfactant, and wherein the second surfactant may or may not be a phospholipid and is more water soluble than the first surfactant; kits for preparing such microbubbles; and methods for using such microbubbles as contrast agents.
Patent CA-2215646-A1 (CA)
Title: Multi-step process to incorporate grain growth inhibitors in wc-co composite
Inventor: SEEGOPAUL PURNESH
IPC: C01B32/949
Filed: 1997-09-11
Abstract: Grain growth inhibitors including vanadium carbide, chromium carbide, tantalum carbide, and niobium carbide are incorporated into a cobalt/tungsten carbide matrix during the formation of the cobalt/tungsten carbide matrix. A precursor powder is formed by combining in solution a cobalt composition, a tungsten composition and a grain growth inhibiting metal composition, which is then spray dried.  The precursor compound is then carburized in carbon monoxide and carbon dioxide to form cobalt/tungsten carbide matrix. This is then further carburized in a hydrocarbon hydrogen gas at an elevated temperature to cause the grain growth inhibiting metal present to form the carbide. The second carburizing step is conducted with a carburizing gas having a carbon activity greater than about 2 for a relatively short period of time at 900° C to 10000° C.
Patent CA-2216530-A1 (CA)
Title: Process for operating an exchange and scaleable digital switch system for carrying out the process
Inventor: SAVORY JESSEL
IPC: G06F3/06
Filed: 1996-03-27
Abstract: A method of operating a switching facility is based on a data base consisting of individual data sets which can be addressed via a key term. The data base is held on a mass store with relatively high access time. To reduce the data access time, a RAM is provided in which the data sets from the data base can be stored. Also provided is a second store area in which a field of pointers to such data sets can be stored, and access occurs in such a way that a field index is derived from the key term. By requesting a pointer to a data set in the first store area, the data set is taken from either the RAM or the mass store. In the latter case, the data set once read out is duplicated in the RAM and an appropriate pointer is entered. For that purpose, a preferably digital and expandable switching system is provided for switching the PCM signals; the said switching system comprises at least one host computer (60), at least one telephone server (70) and a plurality (50) of elementary telephone switching contacts (100, 101...) which are interconnected via a high-speed communications network (80).
Patent CA-2217853-A1 (CA)
Title: Fiber and fiber products produced from feathers
Inventor: GASSNER GEORGE III
IPC: D06M19/00
Filed: 1996-05-17
Abstract: A wide variety of end products may be manufactured from fibers or fiber pulp derived from feathers. Examples of such end products are paper and paper-like products, non-woven and woven fibers, insulation, filters, extrusions, and composite sheets and plates.
Patent CA-2218405-A1 (CA)
Inventor: ACHSTETTER TILMAN
IPC: C12N15/09
Filed: 1996-04-05
Abstract: Novel nucleic acid fragments isolated from the genomic DNA of yeast and having transcription promoter activity, as well as expression cassettes, vectors and host cells containing same, are disclosed. The use of said fragments for producing commercially or therapeutically useful polypeptides is also disclosed.
Patent CA-2218443-A1 (CA)
Title: Metal-containing dna
Inventor: LEE JEREMY S
IPC: H01L51/00
Filed: 1997-12-16
Abstract: The invention provides a DNA molecule comprising a metal-containing DNA molecule, an electron donor electrically coupled to a first end of the metal-containing DNA duplex and an electron-acceptor electrically coupled to a second end of the metal-containing DNA duplex, the metal-containing DNA duplex comprising a divalent metal cation substituted for the imino protons of a DNA base selected from the group consisting of thymine and guanine, the divalent metal cation being selected from the group consisting of Zn2+, Co2+, and Ni2+.
Patent CA-2218500-A1 (CA)
Inventor: SIMPSON JAMES E
IPC: H01J65/04
Filed: 1996-04-22
Abstract: Une lampe à hyperfréquences se compose d'une structure compacte comportant une fente d'accouplement qui est décentrée et orientée dans un sens, et une tige inclinée supportant l'ampoule qui est décentrée et orientée dans le sens opposé. Le guide d'ondes non conventionnel utilisé selon l'invention a approximativement la largeur d'un guide d'ondes WR-284 et approximativement la longueur d'un guide d'ondes WR-340.
Patent CA-2219696-A1 (CA)
Inventor: OLMS JOSEPH JEFFERY
IPC: B60R9/042
Filed: 1997-10-30
Abstract: A motorized rack system for loading and unloading long items such as ladders includes a static rack for holding one end of a ladder and a pivoting and extendible rack. The extendible ladder rack assembly includes a base member mounted to the roof of a vehicle, an elongated pivoting member, and a slideable ladder carriage member. The system also includes a mechanism for positioning the pivotable and extendible ladder rack assembly in a first locked down position of the ladder rack, a second tilted position, and a third tilted/extended position for loading and unloading a ladder. A cable is coupled to the one end of the pivoting member and a cable-spooling mechanism pays out and reels in the cable for positioning the motorized ladder rack.
Patent CA-2221320-A1 (CA)
Inventor: BONFIGLIO GIUSEPPE
IPC: A61N1/30
Filed: 1996-05-15
Abstract: The instrument for iontophoresis has a compact shape and is intended for domestic use, it comprises a grip portion (1) made of an electrically conductive material, one or more batteries (14) and a current regulator (10) received inside the grip portion (1), and a replaceable part (17, 20) for the application of the ionic substance which can easily dissociate and penetrate inside the treated part of organism.
Patent CA-2222321-A1 (CA)
Inventor: REED LEHMAN THOREN
IPC: H01R13/523
Filed: 1997-11-25
Abstract: An elevated  electrical connector  assembly for use with electric submersible pumps.  The assembly is  particularly useful  for wells at elevated temperatures.   The assembly has a removable tubular assembly housing, a removable lower  electrical connector,  a removable annular retainer member,  a removable  crossover sealing  adapter, a removable upper electrical connector,  and  a  removable  locking  member.   The housing is  connected to  a wellhead member and extends out the top of the wellhead.  The electrical connectors are in a part of the housing that  is  outside  of  the  wellhead.    By  elevating  the electrical connectors and their mutual  junctions  away  from  the  hot wellhead, ambient air  can provide sufficient cooling of the assembly to prevent connector failure due to high temperatures.    A  swivel  part  in the tubular  assembly  housing  permits  the  connectors to be angled away from hot components in the flow  path  from  the  wellhead.    A spark containment feature  prevents inadvertent  ignition of combustibles in the surrounding environment cause by spark  generation when  making or breaking electrical contact.
Patent CA-2226997-A1 (CA)
Title: An oscillating stroke reciprocator
Inventor: LUSH ALAN CHARLES
IPC: F16H21/22
Filed: 1998-01-14
Abstract: A linear oscillating stroke reciprocator comprises a frame, a rectilinear post carried by the frame, a carriage mounted on the post for linear motion therealong, and a drive arm pivoted to the frame at one end and connected to the carriage through a lost motion device. This lost motion device takes up longitudinal movements of the drive arm while transmitting movements of the drive arm at right angles thereto to the carriage. The reciprocator includes a rotary drive which drives an eccentric drive. A drive lever is pivotally connected at one end to the drive arm and at the other end to the eccentric.
Patent CA-2229838-A1 (CA)
Title: Method and apparatus for browsing the internet with a telecommunications device
Inventor: SABNANI KRISHAN KUMAR
IPC: H04M1/72445
Filed: 1998-02-18
Abstract: A method and apparatus for browsing the World Wide Web  with  a  telecommunications  device.    A gateway  system provides  the  necessary  communications  links,  data  format changes and protocol conversions to permit a user desiring specific information from the Web to obtain that information via telephone or pager, in either spoken word or alphanumeric form, in response to spoken word or DTMF requests.
Patent CA-2232833-A1 (CA)
Inventor: DUECK RAYMOND
IPC: B65H49/32
Filed: 1998-03-23
Abstract: The present invention provides a powered carousel for storing spools of wire. The wire carousel comprises an upright support frame having a carousel on the support frame mounting a plurality of carrier frames, each carrier frame has a plurality of removable shafts for mounting spools of wire. Each removable shaft is positively secured by a locking mechanism which positively engages each end of the shaft. This helps prevent a shaft from accidentally coming free from the frame and falling from the carousel possibly causing injury to the individual operating the carousel or to bystanders. To provide for the efficient storage of small spools of wire a removable Ferris wheel is mounted on one or more of the shafts. The Ferris wheel includes a plurality of rods for mounting spools of wire arranged annularly therearound and is mounted for rotation on the shaft. The carrier frames have been improved to further improve access to the spools of wire and to improve the stability of the carrier frames. To do this the connection means for mounting the carrier on the carousel has been positioned below the top of the carrier frame. A bottom member has also been added to each carrier frame to prevent wire from hanging down from the frame and getting snagged on a lower frame, on a shaft on a lower frame, or in the drive chain.
Patent CA-2233063-A1 (CA)
Title: Am compatible digital waveform demodulation using a dual fft
Inventor: GEILE MICHAEL J
IPC: H03D1/22
Filed: 1996-08-21
Abstract: The invention provides a method and apparatus for demodulating a composite AM DAB waveform which contains digitally modulated carriers and which employ a mixer (180) for converting a received signal (170) into two signals, the first of these signals represents an in-phase component and the second of the signals represents a quadrature component, two analog-to-digital converters (182, 184) for converting the two signals into digital signals, and two fast Fourier transform elements (188, 190) for extracting data separately from the two digital signals. Complementary digital carrier signals are recovered from the quadrature, and non-complementary digital carriers are derived from a sum of the complementary data and the output of the in-phase component FFT process. Leakage of the AM signal through a highpass filter (186) is prevented from interfering with the demodulation of the complementary carrier signal's use of separated demodulation channels.
Patent CA-2233342-A1 (CA)
Inventor: DE LA POTERIE VALERIE
IPC: A61K8/00
Filed: 1998-04-27
Abstract: L'invention se rapporte à une composition de maquillage des lèvres commercialeme nt viable, comprenant une quantité suffisante d'un système polymérique qui comprend au moins une dispersion de particules de polymère filmogène, ledit système permettant l'obtention d'un film capable de suivre le mouvement des dite s lèvres et/ou sans transfert. Elle se rapporte aussi à un produit de maquillage commercialement viable comprenant un réservoir (2), contenant cette composition, et un moyen amovible de fermeture dudit récipient. Cette composition est en particulier fluide, ce qui nécessite l'emploi d'un organe d'application (4) par exemple du type feutre, et éventuellement d'un essoreur (6)
Patent CA-2233557-A1 (CA)
Title: Label printer with label edge sensor
Inventor: EHRHARDT ROBERT A
IPC: B65C9/44
Filed: 1998-03-30
Abstract: A label printer includes a thermal print head assembly for printing pressure sensitive adhesive-backed labels spaced longitudinally on a web. The print head assembly includes a row of heater elements aligned transversely of the web path and movable toward and away from the web, the heater elements being biased against the web. Mechanical displacement of the print head assembly due to the passage of the leading and trailing edges of the labels beneath the heater elements is sensed by a piezoelectric sensor carried by the print head assembly to locate the printing on the labels with respect to the edges. The sensor may be mounted directly on a pivoting print head or may be mounted on a pivoting support or bracket which carries the print head.      The print head assembly may be of the thermal printing or thermal transfer printing type. Both individual and stacked piezoelectric ceramic transducer elements are disclosed.
Patent CA-2234387-A1 (CA)
Title: Image signal coding system
Inventor: MURAKAMI TOKUMICHI
IPC: H04N19/132
Filed: 1992-10-21
Abstract: An adaptive blocking coding system selects an effective blocking of an input image signal to be encoded in accordance with the correlation between fields, even if motion is detected between the fields.  The blocking patterns include an individual field blocking, a non-interlace blocking, a split blocking and an inverted split blocking.  Further, the coding system searches for motion from both odd and even fields of a frame for producing a motion compensated prediction signal in order to provide high-efficient coding.
Patent CA-2235793-A1 (CA)
Inventor: RIEGLER MANFRED
IPC: B61G11/16
Filed: 1998-04-24
Abstract: An energy-absorbing device, particularly for rolling stock to provide protection therefor when potentially damaging impact occurs, includes first and second tubular elements which are fitted into one another and which are of unlike material.
Patent CA-2237870-A1 (CA)
Title: Combination jacket/sail
Inventor: POWER MARK R
IPC: A41D13/00
Filed: 1998-05-19
Abstract: The jacket has a pouch at each side of the body portion.      A sail is furled within each pouch for storage and may be unfurled for use. The sails are of length approximately equal to the length of a normal arm such that, in use, the sail extends from the pouch and terminates at an end adjacent to the wearer's hand when his arm is generally straight and horizontal. A handle is attached to each distal end to facilitate removal of the sail from the pouch. The sails may alternatively be combined into one continuous piece which is stitched to the rear of the jacket along spaced horizontal lines. When the sail is not in use its ends may be furled and stored in the space between the central portion of the sail and the rear wall of the jacket.
Patent CA-2238674-A1 (CA)
Title: Novel tetracycline resistance protein
Inventor: BURNHAM MARTIN KARL RUSSEL
IPC: A61K35/76
Filed: 1998-07-22
Abstract: The invention provides tetracycline resistance protein polypeptides and DNA (RNA) encoding tetracycline resistance protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tetracycline resistance protein polypeptides to screen for antibacterial compounds.
Patent CA-2240827-A1 (CA)
Inventor: HASEGAWA TAKUYA
IPC: H01M50/491
Filed: 1996-12-25
Abstract: A microporous film made of a high-density polyethylene or a linear copolyethylene having at least two terminal vinyl groups per 10,000 carbon atoms in the polyethylene as measured by infrared spectrophotometry.