baber/WOPTO huggingface dataset:
Patent IL-63205-A0 (IL)
Title: Antiviral 1-aryl-5amino-penten-3-ones
IPC: A61K31/535
Filed: 1981-06-29
Abstract: Described are 1-phenyl-5-amino-1-penten-3-on-derivatives of the general formula <CHEM> wherein R is H, halo, C1-4 alkyl, C1-4 alkoxy, 3,4-methylenedioxy, CF3, NO2, NH2, N(C1-4 alkyl)2, CN, OH, -S(C1-4 alkyl) or -SO2(C1-4 alkyl); R1 and R2 are independently each H or C1-4 alkyl or taken together with the attached N atom are morpholino, piperidino, pyrrolidino, piperazino, or NC1-4 alkyl piperazino; and, when R is halo, C1-4 alkyl or C1-4 alkoxy, x is 0-3 and, otherwise, is 0 or 1; or a pharmaceutically acceptable salt thereof with an acid or for the compounds wherein R1 and R2 are both not H, a quaternary ammonium salt thereof with a C1-4 alkyl halide and a process for their production. The compounds have valuable antiviral activity, e.g for treatment of infections caused by a herpes virus.
Patent IL-66928-A0 (IL)
Title: Disposable pharmaceutical filter assembly
IPC: B01D35/00
Filed: 1982-10-03
Abstract: A disposable unitary filter assembly is provided for filtering pharmaceutical and other fluid materials having a housing of plastic material comprising first and second housing parts (1 and 2) with cooperating peripheral sealing surfaces (1a, 1b; 2a, 2b) extending in at least two planes at an angle to each other of from 30 to 150°. A filter element (8) is disposed in the fluid chamber (7) of the second housing part (2) which comprises a peripheral lip (16) extending into sealing engagement with and between the peripheral sealing surface of each housing part in each plane thereof and is permanently bonded thereto, so that it sealingly closes off the open sides of the fluid chambers (5 and 7) of both housing parts so that fluid communication therebetween is restricted to an opening (15) in an end cap (10) via the filter (8).
Patent IL-70224-A0 (IL)
Title: Glue
IPC: C08J5/12
Filed: 1983-11-14
Abstract: A glue is disclosed which comprises a solution of at least one water-insoluble synthetic organic polymer, such as PVC or ABS, in a solvent which essentially consists of one or several compounds selected from the group consisting of 5- or 6-membered water-miscible lactones or lactams having a melting point of at the most -10 DEG C, a boiling point of at least 200 DEG C and a flash point of at least 90 DEG C, such as N-methyl-2-pyrrolidone or  gamma -butyrolactone. The polymer or polymers may be present in a concentration of between 0.5 and 50%, in particular about 10% by weight. 
<??>The glue may be used at tropical temperatures without problems arising from solvent vapours and without fire risks. The glue is particularly useful for gluing soft PVC articles to hard PVC articles without loss of the sort character of the sort PVC, and for gluing different polymers, such as PVC on polycarbonate or polycarbonate on polyacrylate.
Patent IL-74486-A0 (IL)
Title: Alkene,alkyne or cycloalkylene derivatives
IPC: A61K31/165
Filed: 1985-03-03
Abstract: A compound of the formulawherein X has the formulawherein ring A is phenyl, naphthyl or heterocyclic; wherein R' is hydrogen, alkyl, alkanoyl or aroyl; wherein R<sup>2</sup>, R<sup>3</sup> and R<sup>4</sup>, which may be the same or different, each is an electron withdrawing substituent selected from halogeno, nitro, cyano, trifluoromethyl, alkylthio, alkylsulphinyl and alkylsulphonyl or each is hydrogen, alkyl, alkoxy or dialkylamino provided that when ring A is phenyl or naphthyl at least one of R<sup>2</sup>, R<sup>3</sup> and R<sup>4</sup> is an electron-withdrawing substituent; wherein R<sup>5</sup> and R<sup>6</sup>, which may be the same or different, each is hydrogen, halogeno or alkyl; wherein R<sup>7</sup> is alkyl or halogenoalkyl; and wherein R<sup>S</sup> is carbamoyl, alkyl, cycloalkyl, alkenyl, alkynyl, halogenoalkyl, halogenoalkenyl, halogenoalkynyl, alkanoyl, alkylcarbamoyl, dialkylcarbamoyl or aroyl; or wherein R<sup>8</sup> is alkyl or alkenyl which bears one or more substituents selected from cyano, carbamoyl, amino, hydroxy, alkanoyl, alkoxy, alkylthio, alkenylthio, alkylsulphinyl, alkenylsulphinyl, alkylsulphonyl, alkenylsulphonyl, alkanoylamino, alkoxycarbonylamino, alkylsulphonamido, alkylamino, dialkylamino dialkylsulphamoyl, aroyl, aryl, arylthio, arylsulphinyl, arylsulphonyl, heterocyclylthio, heterocyclylsulphinyl and heterocyclylsulphonyl; or wherein R<sup>8</sup> has the formulawherein ring B is phenyl, naphthyl or heterocyclyl and wherein R<sup>2</sup>, R<sup>3</sup> and R<sup>4</sup> have any of the meanings stated above, provided that when R<sup>7</sup> is methyl R<sup>8</sup> is not also methyl.
Patent IL-74809-A0 (IL)
Title: Live purified marek's disease vaccine
IPC: C12N7/00
Filed: 1985-04-03
Abstract: The invention relates to a highly immunogenic virus preparation derived by attenuation employing serial passages in avian cell cultures and six plaque purification steps from a Marek's disease virus strain, belonging to Avian Herpesvirus serotype-1. The original virus strain MDV CVI-988 was recovered from a healthy chicken (Avian Disease 16:108-125,1972).The live purified Marek's disease vaccine so obtained is innocuous for specific pathogen free Rhode Island Red chickens which are highly susceptible for development of Marek's disease tumours. The monovalent virus preparation, according to the invention, demonstrated in comparison with Marek's disease vaccines based on the same strain, currently in use at a lower cell passage level, an improved protective efficacy against challenge infection by two representatives of virulent Marek's disease virus.The monovalent virus preparation, according to the invention, provided significantly better protection than current MDV CVI-988 vaccine to challenge infection with a representative of the group of newly emerging very virulent strains of Marek's disease virus, MDV RB/1B. The monovalent virus strains of Marek's disease virus, MDV RB/1B. The monovalent virus preparation, according to the invention, provided significantly better protection than is HVT FC126 vaccine to challenge infection with another representative of the group of very virulent MD viruses, MDV Tun.
Patent IL-78227-A0 (IL)
Title: Bonded phase of silica and carboalkoxyalkyl silanes for solid phase extraction
IPC: B01J20/281
Filed: 1986-03-21
Abstract: The reaction product of silica gel or controlled pore glass and carboalkoxyalkyl silanes are suitable for use as packing in solid phase extraction columns for cleanup of urine samples for analysis of cannabinoids.
Patent IL-85599-A0 (IL)
Title: Methods,apparatus and kits for determining the interaction of tissue and various agents
IPC: C12Q1/00
Filed: 1988-03-01
Abstract: The present invention provides methods of, apparatus for, and kits for determining the interaction of tissue and at least one agent by use of at least one tissue equivalent. Tissue equivalent includes, but is not limited to, equivalents of epithelial tissue, connective tissue, cartilage, bone, blood, organs, glands and blood vessels, which are composed of living cells and extracellular matrix molecules, principally collagen. Agent includes, but is not limited to, various substances such as chemicals, cosmetics, pharmaceuticals, stimuli, e.g., light or physical injury; and tissue protective agents.
Patent IL-89589-A0 (IL)
Title: Stable aqueous emulsions of essential oils
IPC: B01J13/00
Filed: 1989-03-13
Abstract: Stable aqueous emulsions of essential oils consisting of  - 1 to 45 parts by weight of an essential oil - 0.01 to 1 part by weight of a nonionic emulsifier chosen from sugar glycerides and sugar esters  - 0.2 to 1.5 parts by weight of xanthan gum  - and the residue to 100 parts by weight of water. They are prepared by dissolving xanthan gum in the nonionic emulsifier and dispersion of the essential oil before or after the addition of xanthan gum. Use for the preparation of aromatising concentrates.
Patent IL-91753-A0 (IL)
Title: 7-substituted derivatives of 3,5-dihydroxyhept-6-ynoic acid,a process for the preparation thereof and pharmaceutical compositions containing them
IPC: A61P3/06
Filed: 1989-09-22
Abstract: 7-Substituted 3,5-dihydroxyhept-6-ynoic acids and the derivatives thereof of the formula I   <IMAGE> I  as well as the corresponding lactones of the formula II   <IMAGE> II  in which R and R DEG  have the specified meanings, a process for the preparation of these compounds, the use thereof as pharmaceuticals and pharmaceutical products are described. In addition, new intermediates for the preparation of the compounds of the formula I or formula II are described.
Patent IL-95020-A0 (IL)
Title: Method of combating pests using substituted pyrimidines and certain such novel compounds
IPC: A01N43/54
Filed: 1990-07-10
Abstract: Methods of combating pests with substituted pyrimidines of the formula I    <IMAGE>  I  where R1 is alkyl, cycloalyl, haloalkyl, alkoxy, alkylthio or substituted or unsubstituted aryl, R2 is halogen or hydrogen, A is oxygen, or sulfur, and X is CH or N, and pyrimidines of the general formula Ia    <IMAGE> Ia  where A is oxygen or sulfur and X is CH or N, and pesticides containing these compounds.
Patent IL-99175-A0 (IL)
Title: Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes,3-aminochromanes,and 3-aminothiochromanes
IPC: C07D311/92
Filed: 1991-08-13
Abstract: The present invention provides novel ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes, 3-aminochromanes, and 3-aminothiochromanes, including their corresponding sulfoxides and sulfones, which ring-substituted compounds exhibit agonist activity at the serotonin 1A receptor, of the formula <CHEM>  in which R is C1-C4 alkyl, C3-C4 alkenyl, or cyclopropylmethyl;     R3 is hydrogen; or R and R3 taken together are a divalent group of the formula -CH2CH2CH2-; R1 is hydrogen, C1-C4 alkyl, C3-C4 alkenyl, cyclopropylmethyl, aryl(C1-C4-alkyl), -COR4, -(CH2)nS(C1-C4 alkyl) or -(CH2)nCONR5R6;     n is an integer from 1 to 4;     R4 is hydrogen, C1-C4 alkyl, C1-C4 alkoxy, or phenyl; R5 and R6 are independently hydrogen, C1-C4 alkyl, or C3-C7 cycloalkyl with the proviso that when one of R5 or R6 is cycloalkyl the other is hydrogen;     X is -CH2-, -O-, -S-, <CHEM>     A is <CHEM> R2 is C1-C8 alkyl, substituted C1-C8 alkyl, C2-C4 alkenyl, aryl, substituted aryl, aryl(C1-C4-alkyl), substituted aryl(C1-C4 alkyl), C3-C7 cycloalkyl-substituted methyl, or C3-C7 cycloalkyl; and pharmaceutically acceptable acid addition salts thereof.
Patent AU-PR421501-A0 (AU)
Title: Potting method
IPC: B01D63/00
Filed: 2001-04-04
Abstract: A membrane module includes at least one hollow fiber membrane; a first resin layer formed around an end of the at least one hollow fiber membrane; and a second resin layer chemically bound to the first resin layer, wherein the second resin layer is of greater flexibility than the first resin layer.
Patent FI-20020026-A0 (FI)
Inventor: HAUMONT SERGE
IPC: H04W28/00
Filed: 2002-01-08
Abstract: The invention relates to the packet switched portion of a mobile communications system in which two or more network operators share the same network. To allow the operators to compete with each other, they usually have a gateway node (GGSN1, GGSN2) of their own, although they share the serving node (SGSN1). In order to enable the selection of the gateway node (GGSN1, GGSN2), the invention involves maintaining information about predefined partner networks, i.e. shared networks an operator has in addition to its own networks. On the basis of the information a mobile station (MS2) can be connected to a gateway node (GGSN2) of its home network (PLMN2), provided that the visited network (PLMN1) is a partner network of the home network (PLMN2). A visiting mobile station from outside the partner networks, however, can be connected to the visited gateway node (GGSN1).
Patent FI-20070162-A0 (FI)
Inventor: PAASONEN LAURI
IPC: A61K41/00
Filed: 2007-02-27
Abstract: Method for releasing a material in a controlled manner from amphiphilic compounds. The material to be released is enclosed inside a membrane formed of an amphiphilic compound, in which or inside which membrane noble-metal nanoparticles are incorporated. Light of a sufficiently strong intensity is directed to the amphiphilic compounds for a sufficiently long time for the membrane to change phase, as a result of the increase in temperature, and to open an exit path for the material.
Patent FI-20095035-A0 (FI)
Inventor: BOECKHOFF NICOLAUS
IPC: F02M/
Filed: 2009-01-16
Abstract: The invention relates to an inspection method for an ignition liquid ejector, in which an ejecting moment and/or an ignition moment of the ignition liquid deviated from a fuel ignition moment is detected during an operation period. Firing of the ejected ignition liquid is staggered in time. The staggered firing is detected by a measuring device. Thus, the ignition liquid ejector which does not operate regularly is identified during a liquid fuel operation period.
Patent FI-20106395-A0 (FI)
Inventor: JANKA KAUKO
Filed: 2010-12-31
Abstract: The present invention relates to an apparatus (1) for monitoring particles in a channel (11) or a space comprising aerosol and to an ion trap arrangement in the apparatus. The apparatus (1) comprises an ejector (24), gas supply (6, 16, 18, 19) arranged to feed an essentially particle free ionized gas flow (C) to the ejector (24), a sample-inlet arrangement (2) arranged to provide a sample aerosol flow (A) from the channel (11) into the ejector (24) by means of suction provided by the gas supply (6, 16, 18, 19) and the ejector (24) for charging at least a fraction of the particles of the sample aerosol flow (A), and an ion trap (12) extending at least partly into ejector (24) for removing ions not attached to the particles. According to the invention the ion trap (12) is a provided as a metal trap wire.
Patent IL-104740-A0 (IL)
Title: Hypolipidaemic compounds,their preparation and pharmaceutical compositions containing them
IPC: A61P9/10
Filed: 1993-02-16
Abstract: PCT No. PCT/GB93/00328 Sec. 371 Date Dec. 5, 1994 Sec. 102(e) Date Dec. 5, 1994 PCT Filed Feb. 16, 1993 PCT Pub. No. WO93/16055 PCT Pub. Date Aug. 19, 1993The present invention is directed to the following compounds of formula (I):    <IMAGE>  (I)  wherein l is an integer of from 0 to 4; m is an integer of from 0 to 5; n is an integer of from 0 to 2; R and R' are atoms or groups independently selected from halogen, nitro, phenylalkoxy, C1-4 alkoxy, C1-6 alkyl and -O(CH2)pSO3R'' wherein p is an integer of from 1 to 4 and R'' is hydrogen or C1-6 alkyl, wherein said phenylalkoxy, alkoxy and alkyl groups are optionally substituted by one or more halogen atoms; R4 is a C1-6 straight alkyl group; and R5 is a C2-6 straight alkyl group; and their salts, solvates and physiologically functional derivatives, with processes and novel intermediates for their preparation, with pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidaemic conditions, such as atherosclerosis.
Patent IL-126993-A0 (IL)
Title: Siloxane and siloxane derivatives as encapsulants for organic light emitting devices
IPC: B05D3/02
Filed: 1996-07-10
Abstract: An organic light emitting device (10) is provided which is encapsulated by a Siloxane film (17). This Siloxane film (17) is applied to the light emitting portion of the diode (10) providing for protection against contamination, degradation, oxidation and the like. The Siloxane film (17) carries an optical element, such as a lens (18) for example. This optical element (18) is arranged such that the light generated inside the diode (10) is output through it.
Patent IL-127575-A0 (IL)
Title: Prenyl transferase inhibitors
IPC: C07K5/06
Filed: 1997-05-29
Abstract: A family of compounds capable of inhibiting the activity of prenyl transferases. The compounds are covered by either of the two following formulas     Each of the R groups is defined in the disclosure
Patent IL-128323-A0 (IL)
Title: Purine inhibitors of cyclin dependent kinase 2
IPC: A61K31/52
Filed: 1997-08-01
Abstract: A 2,6,9-trisubstituted purine composition having the following formula:   <IMAGE>   where X is a amino, oxo, thio, of sulfone moiety, R1 is a lower alkyl, substituted lower alkyl, cycloalkyl, substituted cycloalkyl, cycloheteroalkyl, substituted cycloheteroalkyl, aryl, substituted aryl, heterocycle, hetaryl, substituted hetaryl, aralkyl, heteroaralkyl, heteroalkyl, alkyl alkenyl, alkyl alkynyl, alkyl cycloalkyl, or alkyl cycloheteroalkyl, each having from 1 to 20 carbon atoms; R2 is hydrogen, lower alkyl, substituted lower alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heterocycle, hetaryl, substituted hetaryl, aralkyl, heteroaralkyl, heteroalkyl, alkyl alkenyl, alkyl alkynyl, alkyl cycloalkyl, or alkyl cycloheteroalkyl; and R3 is halogen, hydroxyl, thio, alkoxy, alkylthio, lower alkyl, -NR4R5 or a component having the formula:   <IMAGE>   wherein when R3 is 2-hydroxyethylamino and R2 is methyl, R1-X is not amino, 3-methyl-2-butenylamino, benzylamino, or m-hydroxybenzyl-amino, when R3 is 2-hydroxyethylamino and R2 is isopropyl, R1-X is not benzylamino, m-hydroxybenzylamino, or 3-methylbutylamino, when R3 is 2-hydroxyethylamino and R2 is 2-hydroxyethyl, R1-X is not benzylamino and when R3 is selected from the group consisting of 2-propanol-2-methylamino and 2-dimethylaminoethylamino and R2 is methyl, then R1-X is not benzylamino.
Patent IL-137811-A0 (IL)
Title: Vaccines comprising interleukin-12 and herpes simplex viral antigen
IPC: A61P31/12
Filed: 1999-02-10
Abstract: This invention pertains to vaccine compositions comprising a mixture of antigen, such as a herpes simplex virus antigen, and the interleukin IL-12, which may be adsorbed onto a mineral in suspension. These vaccine compositions modulate the protective immune response to the antigen.
Patent IL-138801-A0 (IL)
Title: Humanized antibody against human tissue factor and process for the preparation thereof
IPC: C12P21/08
Filed: 1999-04-02
Abstract: A humanized antibody against tissue factor (TF), comprising: 
A: a humanized H chain comprising (1) a H chain V region comprising the H chain CDRs of a mouse monoclonal antibody against TF and the H chain FRs of a human antibody, and (2) the H chain C region of a human antibody; and 
B: a humanized L chain comprising (1) an L chain V region comprising the L chain CDRs of a mouse monoclonal antibody against TF and the L chain FRs of a human antibody, and (2) the L chain C region of a human antibody.  After generating a humanized V region by grafting the CDRs of a mouse monoclonal antibody onto a human antibody, a humanized antibody having a higher activity is searched by replacing the FR of the above region with the corresponding FR of the human antibody having a high homology.
Patent IL-143697-A0 (IL)
Title: Use of biochemical substances for a composition for the prevention and treatment of health conditions caused by constriction of smooth muscle cells in organs of the human body
IPC: A61K33/32
Filed: 2001-06-12
Abstract: The invention relates to the use of biochemical substances for a composition for the prevention and treatment of health conditions caused by constriction of smooth muscle cells in organs of the human body like high blood pressue, asthma, glaucoma and tinnitus.
Patent IL-144653-A0 (IL)
Title: Process for quality control and standardisation of medicinal plant products
IPC: G01N33/483
Filed: 2000-02-10
Abstract: A process for establishing a standard specification for a medicinal plant material comprises: (i) preparing a test solution or test extract of a sample of the medicinal plant material which is known to possess the or each property required for the standard; (ii) submitting the said solution or extract to two or more analytical methods including (a) a combination of NMR spectroscopy and a computer-based pattern recognition technique, and (b) one or more biological profiling techniques; (iii) obtaining results from the analytical methods used in step (ii); and (iv) establishing a standard specification for the said plant material on the basis of the results obtained in step (iii). Candidate samples of the medicinal plant material may subsequently be tested for compliance with the standard. They can be accepted or rejected depending on whether they give analytical results which fall within or outside either part or all of the specification established in step (iv). This approach to standardization and quality control is particularly applicable to mixtures of medicinal plant materials.
Patent IL-147713-A0 (IL)
Title: Catheter for uniform delivery of medication
IPC: A61M25/16
Filed: 2000-07-19
Abstract: The present invention provides a catheter for the delivery of fluid medication across an anatomical region. In accordance with one embodiment, the catheter comprises an elongated tube with a plurality of exit holes along an infusion section of the catheter, and an elongated flexible porous member residing within the tube and forming an annular space between the tube and the member. In accordance with other embodiments, the catheter includes a tube having a plurality of exit holes in a side wall of the tube. The exit holes may combine to form a flow-restricting orifice of the catheter. Advantageously, fluid within the catheter flows through all of the exit holes, resulting in uniform distribution of fluid within an anatomical region. In one particular embodiment, the catheter comprises a tube having elongated exit slots therein. In accordance with other embodiments, the catheter includes an elongated tubular member made of a porous membrane. The porous membrane is configured so that a fluid introduced into an open end of the tubular member will flow through side walls of the tubular member at a substantially uniform rate along a length of the tubular member. In accordance with other embodiments, the catheter includes an elongated "weeping" tubular coil spring attached to an end of, or enclosed within, a tube. Fluid within the spring and greater than or equal to a threshold pressure advantageously flows radially outward between the spring coils. Advantageously, the fluid is dispensed substantially uniformly throughout a length of the spring.
Patent IL-150109-A0 (IL)
Title: Method for administering a cytokine to the central nervous system and the lymphatic system
IPC: A61P31/18
Filed: 2000-12-08
Abstract: The present invention is directed to a method for delivering cytokines to the central nervous system and the lymphatic system by way of a tissue innervated by the trigeminal nerve and/or olfactory nerve. Cytokines include tumor necrosis factors, interleukins, interferons, particularly interferon-beta and its muteins such as IFN-beta<SUB>ser17</SUB>. Such a method of delivery can be useful in the treatment of central nervous system disorders, brain disorders, proliferative, viral, and/or autoimmune disorders such as Sjogren's disorder.
Patent IL-158940-A0 (IL)
Title: Elementary and complex coupling devices, and their use
IPC: F16B1/00
Filed: 2003-11-18
Abstract: This invention relates to elementary and complex coupling devices. In particular, such coupling devices may be used for supporting radar, antenna or optical sensor equipment, notably on vessels. <??>An object of this invention is an elementary coupling device comprising:  A means for stiffening 1 the elementary coupling device against torsion, Two means for linking 2' and 2" the means for stiffening 1 to a second object to be coupled 4o, Two first means for hinging 2/4' and 2/4" each means for linking 2' and 2" directly or indirectly on the second object to be coupled 4o at two separate points, Two second means for hinging 1/2' and 1/2" the means for stiffening 1 on each means for linking 2' and 2" at two separate points, Two third means for hinging 1/3', 1/3" the means for stiffening 1 directly or indirectly on a first object to be coupled 3o at two separate points.  <??>A further object of this invention is a complex coupling device comprising three of these elementary coupling devices. <IMAGE>