baber/WOPTO huggingface dataset:
Patent MY-166823-A (MY)
Title: Adjustable fastener for clamping sheets
Inventor: LOU MING TICK
IPC: B42F13/14
Filed: 2013-02-26
Abstract: An adjustable fastener (1) for clamping sheets comprising a male component (2) having a body (3) and a rod (4) extending perpendicularly from the body and a female component (5) having a body (6), an aperture (7) through the body, and at least two collars (8) formed about the aperture. The rod of the male component is insertable through said aperture and is releasably engageable by the collars of the female component in a ratchet action to adjust the size of a gap between said bodies for clamping said sheets. The height of the collars relative to the length of the rod allows the rod to extend through said aperture and protrude outside the body of the female component. (Figure 1)
Patent SG-10201610859V-A (SG)
Title: Suspension type lifting device
Inventor: CHUAN-SHAN HUANG
IPC: B66C1/10
Filed: 2016-12-27
Abstract: OF THE DISCLOSURE SUSPENSION TYPE LIFTING DEVICE A suspension type lifting device include s a base unit, a bearing unit, a 5 balance unit, a servo unit a nd a hanging unit. The base unit includes a first plate, a second plate and a third plate. The bearing unit includes a positioning piece and two forks. The balance unit is connect ed with the third plate of the base unit. The servo unit is connected with the first plate of the base unit. The hanging unit is mounted on the first plate of the base unit. When the servo unit 10 detects that a foreign object is placed on the bearing unit, the servo unit calculates a value required for reaching a balance wei ght and transmits a power to drive the balance unit to swing leftwa rd and rightward, so as to reach a balance state. Fig 1
Patent SG-10201705954V-A (SG)
Title: A pharmaceutical composition for use in the treatment or prevention of a c5-related disease and a method for treating or preventing a c5-related disease
Inventor: SHINOMIYA KENJI
Filed: 2017-07-20
Abstract: A PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OR PREVENTION OF A C5-RELATED DISEASE AND A METHOD FOR TREATING OR PREVENTING A C5-RELATED DISEASE The present invention relates to pharmaceutical compositions for use in the treatment or prevention of a C5-related disease and methods for treating or preventing a C5-related disease. The present invention further relates to dosages and administrations of anti-C5 antibody or pharmaceutical compositions containing the anti-C5 antibody. [No suitable figure]
Patent SG-10201805461W-A (SG)
Title: Semiconductor device
Inventor: JUN-WON LEE
IPC: H01L27/108
Filed: 2018-06-26
Abstract: A first bit line structure is disposed between a first contact structure and a second contact structure. A first air spacer is interposed between the first contact structure and the first bit line structure. A first separation space is connected to an air entrance of the first air spacer and interposed between the first contact structure and the first bit line structure. A cover insulating pattern with a gap portion is interposed between the first contact structure and the second contact structure. The gap portion has a downwardly-decreasing width. An air capping pattern covers the cover insulating pattern to seal the first separation space. [FIG. C] 49
Patent SG-10201900002Q-A (SG)
Title: Antibody molecules to pd-1 and uses thereof
Inventor: FREEMAN GORDON
Filed: 2015-01-23
Abstract: ANTIBODY MOLECULES TO PD-1 AND USES THEREOF Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders. (Figure 3A)
Patent SG-10201909401U-A (SG)
Title: Oral delivery product
Inventor: GOODE MICHAEL A
IPC: A61K33/24
Filed: 2016-01-05
Abstract: ORAL DELIVERY PRODUCT This invention provides a nutritional supplement composition that can be taken anytime or anywhere without water or other liquid which is usually required for swallowing a tablet. The present invention is a nutritional supplement composition which is a convenient, flavorful and enjoyable vitamin mint which can be ingested without water. No Figure
Patent SG-11201809894U-A (SG)
Title: Simulation apparatus, simulation method, and computer program
Inventor: FUJIWARA MASAYASU
IPC: G06Q10/04
Filed: 2017-02-28
Abstract: A simulation related to a lining-up behavior in a transport system is easily performed. A simulation apparatus for simulating a lining-up behavior of a passenger of a transport system, when executing a simulation such that each passenger boards the transport system after lining up at any one of a plurality of boarding/alighting gates in a boarding area and alights from the transport system at the boarding/alighting gate at which the passenger boards the transport system in an alighting area, calculates a degree of attractiveness of each boarding/alighting gate to the passenger on the basis of the number of lining-up passengers at the boarding/alighting gate at a time of arrival of the passenger at the boarding area, and determines a boarding/alighting gate at which the passenger lines up on the basis of the calculated degree of attractiveness.
Patent SG-11201907022T-A (SG)
Title: Virtual reality head-mounted apparatus
Inventor: ZHANG HONG
IPC: G02B27/01
Filed: 2018-02-26
Abstract: Provided is a virtual reality head-mounted apparatus, including: an apparatus body () and at least one heat-generating element (2A, 4). The apparatus body (1) includes at least one installation space (10) and at least one heat dissipating channel (3) having a non-straight-line structure. The heat-generating element (2A, 4) is installed in the installation space (10). Two ends of the heat dissipating channel (3) are in connection with the installation space (10) and an exterior of the apparatus body (1) respectively. The virtual reality head-mounted apparatus can improve heat dissipation performance, and also prevent external light from entering, thus ensuring immersive virtual reality experience for a user. 12
Patent SG-11201909303T-A (SG)
Title: Point of delivery cold slurry generation
Inventor: VELIS CHRISTOPHER
IPC: A61B18/02
Filed: 2018-04-05
Abstract: WO 18/ 18757 3 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 11 October 2018 (11.10.2018) WIPO I PCT omit °noI0 moIIV100im0111111 OIIIIII (10) International Publication Number WO 2018/187573 Al <=1 (51) International Patent Classification: A61F 7/12 (2006.01) A61B 18/02 (2006.01) A61F 7/00 (2006.01) (21) International Application Number: PCT/US2018/026260 (22) International Filing Date: 05 April 2018 (05.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/482,003 05 April 2017 (05.04.2017) US (71) Applicant: ARCTIC FOX BIOMEDICAL, INC. [US/US]; 97 Winthrop Street, Harvard Square, Cambridge, MA 02138 (US). (72) Inventor: VELIS, Christopher, J.P.; 97 Winthrop Street, Harvard Square, Cambridge, MA 02138 (US). (74) Agent: MEYERS, Thomas, C. et al.; Brown Rudnick LLP, One Financial Center, Boston, MA 02111 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 2 I (3)) (54) Title: POINT OF DELIVERY COLD SLURRY GENERATION 130 FIG. 1 (57) : The present invention provides methods and devices for making a cold slurry at a point of delivery. A point of delivery device deliver4s cold slurry components to a location at or near a target tissue. The components are combined to form the cold slurry at or near the point of delivery. This approach to generating a cold slurry at the point of delivery allows the characteristics of the cold slurry, such as temperature, particle shape and particle size, to be maintained and controlled.
Patent HU-211071-B (HU)
Inventor: PAPP GYOERGY
IPC: A23K50/15
Filed: 1991-01-04
Abstract: A találmány tárgya eljárás hozamfokozó hatással rendelkező, fémezüsttel preparált aktívszén készítmények előállítására. A találmány szerinti eljárásban egyszerű ezüst-sók, előnyösen ezüst-nitrát vizes oldatával telítik a karboxil funkciós csoportot tartalmazó, hidrogén vagy kálium formába hozott sztirol-divinil-benzol kopolimer alapú ioncserélő műgyantákat, majd az így kapott anyagot levegőn való szárítás után 500-1000 *C-os nitrogénáramban karbonizálják. A terméket búzakorpával vagy más takarmánnyal 0,01-10 tömeg%-osra hígítják, és az így kapott premixből 0,5% mennyiséget kevernek az állatok takarmányába. ffl HU 211 071 A leírás terjedelme: 2 oldal
Patent IS-2684-B (IS)
Inventor: SUN QUN
IPC: A61P29/00
Filed: 2005-12-01
Abstract: Piperidine Compounds; compositions comprising a Piperidine Compound; and methods for treating or preventing pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia, or depression in an animal comprising administering to an animal in need thereof an effective amount of a Piperidine Compound are disclosed. In embodiment, the Piperidine Compound has the formula:   
and pharmaceutically acceptable salts thereof, wherein Ar 1 , Ar 2 , X, R 3 , R 4 , and m are as disclosed herein.
Patent AT-404387-B (AT)
Title: Internal combustion engine having two inlet valves and one outlet valve per cylinder
Inventor: VALEV ASSEN DIPL ING DR
IPC: F01L1/18
Filed: 1991-03-04
Granted: 1998-11-25
Abstract: In an internal combustion engine having two inlet valves 1, 2 and one outlet valve 5 per cylinder, an overhead cam shaft 7 which operates the said valves (which have at least approximately parallel axes) via bucket tappets 3, 4, 5, in which case two of the said valves are operated directly by in each case one cam 8, 10 and the third valve is operated via a further cam 9 and via a rocker lever 11 whose axis is located above the cam shaft, it is proposed in order to reduce the space requirement that the plane 20 through the rocker lever axis 19 and the axis through the centre of curvature of the contact surface to the bucket tappet 4 and the axis 13' of the roller 13 with the axis 2' of the bucket tappet 4 includes an angle a which is considerably different from a right angle, so that the contact with the associated bucket tappet 4 takes place on its end surface 4" along a region 14 on the bucket tappet 4 which is located at least approximately symmetrically with respect to the centre of the end surface 4' of the bucket tappet 4. <IMAGE>
Patent AT-409280-B (AT)
Title: Prestressing cable - has specified plastic individual strand and overall insulation
IPC: E04C5/08
Filed: 1989-04-12
Granted: 2002-07-25
Abstract: A bunch of structural elements to prestress load supporting framework or to act as anchoring link or inclined cable for supension bridges, consists of the strands (1) which are arranged around a central core strand (1'). A soft plastic material (3) such as PE has been extruded to cover them and to fill the voids between them. The corrosion resistance is improved, if the individual strands are coated by a rigid plastic (4).
Patent DK-158916-B (DK)
Inventor: BEDIER PIERRE CHARLES ALFRED
IPC: D04B1/24
Filed: 1981-02-19
Abstract: The present invention relates to a process for making mesh tights or panty-hose, with seam and elastic belt incorporated therein, and to tights obtained thereby. Over the height of the elastic belt, in a strip of about 2 cm width on either side of the slit made for joining two hose elements by a seam, an elastic yarn is knitted with one needle out of two, on the needles of the strip with the exception of the central needle, then the basic yarn is knitted on all the needles of the circular machine used, the hose elements are slit along the wale of the central needle and are joined by a seam.
Patent HU-183800-B (HU)
Inventor: KOVACS GYULANE
IPC: C04B33/13
Filed: 1982-02-02
Abstract: A találmány a különböző területeken keletkező olajos iszapok ártalommentes elhelyezését szolgálja. Az olajos iszapot a téglagyártásnál használt agyaghoz keveijük és az így bekevert alapanyagot a gyártás során egyébként is használt technológiával kiégetjük. Az égetés során megsemmisül a környezetkárosító olajos iszap. Az eljárással kiváltjuk az esetenként alkalmazott szénport, így energiát takarítunk meg.  -1-
Patent HU-190707-B (HU)
Inventor: HIDEG KALMAN
IPC: A61K31/505
Filed: 1983-02-04
Abstract: A találmány tárgya eljárás 1 általános képletű - ahol A jelentése kívánt esetben hidroxil-csoporttal szubsztituált 1-4 szénatomos alkilén-csoport, B jelentése egyes vagy kettős kötés, R jelentése 1-4 szénatomos alkil-csoport új anlian hatású kinazolon-származékok savaddiciós sói előállítására. E vegyületeket úgy állítjuk elő, hogy II általános képletű ahol A és B jelentése a fenti karboxamid-származékot egy ΙΙΓ általános képletű - ahol R jelentése a fenti - benzoxazinon-származékkal kondenzálunk, majd a kapott kinazolon-származékból savval sót képeznek.  90707 -1-
Patent HU-201239-B (HU)
Inventor: A FELTALALOK NEVUEK FELTUENTET
Filed: 1989-02-03
Abstract: A találmány szerinti készítmény 80-95 tőmeg% emulziót és 5-20 tömeg% hajtógázt tartalmaz, ahol az emulzióban 5-25 tömeg% füijtojás, 10-33 tömeg% mosóaktív anyag/anyagok, előnyösen zsírsav-amido-alkil-betain, zsírsav-glicerid-poli(etilén-glikol)-éter, hidroxi-etil-alkil-ainmónium-foszfát és/vagy vinil-pirrolidon-kopolimer, 55-75 tömegei víz, 0-5 tömeg% kozmetikai adalékanyag/anyagok, előnyösen szerves karbonsav és/vagy illatanyag, továbbá színezék és tartósítószer van jelen, és az emulzió színezékként és tartósítószerként 0,1-5,0 tömeg% (I) képletű 7-(trimetilammónium) -1 -[(3 -nitro -4-amino- fenU) -azo]-beta- naftol-kloridot és/vagy (Π) képletű 7-(trime- til-ammónium)-l-((2-nitro-4-amino-fenil)-azo]beta-naftol-kloridot és/vagy (III) képletű 7-(trimetil-ammónium)-l-[(4-amino-fenil)-azo]-beta- naftol-kloridot és/vagy (IV) képletű 7-(trimetil-ammónium)-l-[(2-metoxi-fenil)-azo]-beta-naftol- kloridot és/vagy (V) képletű 2-br6m-imino-5-hidroxi-6[3-(trimetil-ammónium)-fenil-amino]-8-aminonaftokinon/l,4/-kloridot és/vagy (VI) képletű 2,6dibróm-4-imino-5-hidroxi-8-[3-(trimetíl- ammónium)-fenil-amino]-naftokinon/l,4/-kloridot és/vagy (VII) képletű l-fenil-2-hidron-3-I3-(trimetil-ammónium)-fenil-azo]-4-metil-pirazol-kloridot tartalmaz 3-5 közötti pH-értéken.  (I) G0  (111)  A leírás tejedelme: 7 oldal, 2 ábra HU 201 239 A -1-
Patent HU-218272-B (HU)
Title: Oxetanone derivatives, pharmaceutical compositions comprising same and process for producing them
Inventor: DR DERUNGS ROMANO
IPC: A61P43/00
Filed: 1991-02-20
Abstract: Novel oxetanones inhibiting pancreatic lipase, of the formula <IMAGE> in which Q, R<1> and R<2> have the meaning given in the description, are disclosed, which are prepared starting from the corresponding beta -hydroxycarboxylic acids.
Patent HU-191325-B (HU)
Inventor: NAGY ISTVAN
IPC: B30B9/22
Filed: 1980-03-26
Abstract: A találmány vertikális kézisajtókhoz alkalmazható gumitömlős nyomóberendezés, amellyel, sajtókosártérbe helyezve, a kézisajtó mechanikus működtetése mellett hidraulikus, illetőleg pneumatikus sajtolás is megvalósulhat. Ezzel a kézi sajtók újabb technológiai eljárással is használhatók, kisebb fizikai munkával és nagyobb teljesítménnyel.  -1-
Patent MX-169226-B (MX)
Title: Composicion aditiva para combustibles
Inventor: BOWERS WAYNE E
IPC: A46B9/06
Filed: 1985-12-03
Abstract: La presente invención se refiere a una composición aditiva para combustibles, para un combustible seleccionado del grupo consistente en combustible de gasolina y combustible diesel que comprende una solución de un compuesto de coordinación de un metal del grupo del platino, soluble en el disolvente, de fórmula: en donde M es un metal del grupo del platino y R es fenilo, bencilo o nitrobencilo, en un disolvente de hidrocarburo oxigenado, en cantidades suficientes para suministrar un metal del grupo del platino y oxígeno en una relación en peso de oxígeno a metal del órden de 1,000:1 a 1000,000:1.
Patent ZA-91560-B (ZA)
Title: Transdermal therapeutic system comprising tulobuterol as active substance
Inventor: HOFFMAN HANS-RAINER
IPC: A61M37/00
Filed: 1991-01-25
Abstract: The invention relates to a transdermal therapeutic system containing tulobuterol or one of its pharmaceutically compatible salts as active ingredient, comprising a backing layer which is essentially impermeable to active ingredient, and at least one matrix layer which contains the active ingredient and contains at least one styrene/1,3-diene/styrene block copolymer, and to a process for the production thereof.
Patent ZA-96528-B (ZA)
Title: 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders
Inventor: BRIDGES ALEXANDER JAMES
IPC: A61K31/352
Filed: 1996-01-23
Abstract: 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran inhibits MEK and, as such, is effective in treating cancer and other proliferative diseases such as psoriasis and restenosis.
Patent ZA-97523-B (ZA)
Title: Printable film
Inventor: SERVANTE ALASTAIR HUGH
IPC: C08J7/044
Filed: 1997-01-22
Abstract: The invention relates to printable films comprising a substrate and at least a surface layer, said layer covering at least one face of said substrate and comprising a water-dispersible polymer and an ethylenically unsaturated compound; to a process for the manufacture of such films; to printed films and especially to printed labels obtained from such printable films.
Patent AT-403076-B (AT)
IPC: E05C7/06
Filed: 1994-06-08
Granted: 1997-11-25
Abstract: A hinge with a hinge bowl 1 which is connected to a hinge arm 3 via one axis of articulation or four axes of articulation 4 and two articulated levers 2. It has a flange 24, on which dowel pegs 25 are supported by means of holding pins 37. The holding pins 37 are radially displaceable in the dowel pegs 25 as a result of the rotation of the hinge bowl 1. <IMAGE>
Patent AT-403644-B (AT)
Title: Wild animal fender
IPC: A01M29/00
Filed: 1995-10-10
Granted: 1998-04-27
Abstract: The wild animal fender consists of a container 1 receiving odorous substances, of a cover 5 arranged over the container 1 and of a carrying rod 3, the carrying rod 3 passing through the container 1 and the cover 5, and the container 1 and cover 5 being held on the carrying rod 3 by means of clamping pieces 4 capable of being attached to the carrying rod 3. <IMAGE>
Patent AT-405818-B (AT)
Title: Installation for conveying goods and/or persons by means of a continuous conveying belt or the like
IPC: B65G17/22
Filed: 1996-12-10
Granted: 1999-11-25
Abstract: Installation for conveying goods and/or persons by means of a continuous conveying belt 1 or the like which is guided over deflecting drums at the two ends of the installation and is designed with supports 2 which are spaced apart from one another in the conveying direction, extend transversely to the conveying belt and at the two ends of which there are mounted rollers 3 which roll along supporting devices 4, 5, the top strand of the conveying belt 1 or the like being fastened on the underside of the supports, and the rollers 3 rolling on the top side of the supporting devices 4, 5. In this case, the supports are designed as single-piece bars 2 and the conveying belt 1 is designed, in a manner known per se, as a corrugated-edge conveying belt, the corrugated edges 11 being subdivided into individual sections by the bars 2, and the ends of the sections being fastened on the side surfaces of the bars 2. <IMAGE>
Patent AT-400454-B (AT)
Title: Joint covering, in particular dilation joint seal in bridge structures
IPC: E01D19/06
Filed: 1989-12-01
Granted: 1996-01-25
Abstract: A two-part joint covering is disclosed, formed by an own supporting part 2 and a flexible seal 5, which are spatially separate from one another and individually exchangeable independently of one another. The supporting part has a fixed bearing part and a sliding bearing part, the sliding bearing part being toothed. The fixed bearing part has a convex bearing surface 7 and a screw connection 3, by means of which a bearing pressure is ensured in the region of the sliding surfaces, so that contaminations cannot get into the interior of the joint seal. For this purpose, the toothing parts have scraping surfaces 8, provided in particular at an inclination of 45 degree to the bearing surface, at the tip of the teeth and at the root of the teeth. <IMAGE>
Patent AT-383845-B (AT)
Title: Nail plate
Inventor: WOLF JOHANN
IPC: F16B15/00
Filed: 1985-11-18
Granted: 1987-08-25
Abstract: A nail plate 3 for connecting beams 1 to supports comprises a sheet-metal plate 8 out of which nails 4, 5 are forced by tongue-like punchings 6, 7. The nails 5 arranged in the border regions 9, 10 are longer, set more closely together or provided with a larger surface area, e.g. a larger cross section, than the nails 4 provided in the interior 11 of the plate, in order thus to increase the level to which the nails 5 around the border adhere in the wood of the beams 1. <IMAGE>
Patent AT-388213-B (AT)
Title: Liquid cooling, in particular for internal combustion engines of motor vehicles
Inventor: KAUER ERHARD ING
IPC: F01P11/02
Filed: 1984-12-17
Granted: 1989-05-26
Abstract: In a liquid cooling intended particularly for internal combustion engines of motor vehicles, a compensating tank 2 for the cooling liquid, connected to a heat exchanger 1, is provided. This compensating tank 2 has a closeable filling orifice 6 and a safety valve 10. In order to save on construction height, the compensating tank 2 consists of two individual tanks 2a, 2b which are arranged next to one another and are line-connected near the bottom. Only one 2a of the two individual tanks 2a, 2b is provided with the filling orifice 6, the safety valve 10 and the connecting line 7 to the heat exchanger 1. <IMAGE>
Patent DK-155353-B (DK)
Inventor: MCCREERY JAMES FRANCIS
IPC: B23B27/16
Filed: 1981-08-20
Abstract: A cutting insert for the metalworking industry is disclosed having a cutting edge, a land area. a descending wall and a sloping wall that joins a planar floor in the central portion of the insert. The cutting insert is polygonal when. viewed in plan and has rounded corners joining the sides of the insert. The insert has at least two angularly related cutting edges defining a plane. The perpendicular distance between the plane defined by the cutting edges and the point where the descending wall joins the sloping floor is at a minimum in the corner areas and at a maximum intermediate the adjacent corners of the insert (Fig. 1).
Patent DK-164903-B (DK)
Inventor: KARJALAINEN ARTO JOHANNES
IPC: C07D233/64
Filed: 1985-11-22
Abstract: The compounds of the formula: <CHEM> wherein X is -CH2-, -CH2CH2- or -0-, R1 is H, lower alkyl or lower alkenyl group, OCH3 or OCH2CH3, R2 is H, CH3, CH2CH3, OCH3 or OH, R3 is H, CH3, CH2CH3, OCH3 or Hal, R4 is H, CH3, CH2CH3, OCH3 or Hal, and Hal is halogen, and their non-toxic acid addition salts exhibit valuable pharmacological activity and are useful especially as selective  alpha 2-receptor antagonists. Processes for the preparation of these compounds and pharmaceutical compositions containing them are described.