baber/WOPTO huggingface dataset:
Patent DE-69630307-D1 (DE)
Inventor: MCEVER P
IPC: C12N15/09
Filed: 1996-08-02
Granted: 2003-11-13
Abstract: Tyrosine sulfate on PSGL-1, particularly at least one of residues (46, 48) and (51), functions in conjunction with sialylated and fucosylated glycans, most preferably Thr-57, to mediate high affinity binding to P-selectin. PSGL-1 O-glycans have been determined to consist of disialylated or neutral forms of the core-2 tetrasaccharide Gal beta 1}4G1cNAc beta 1}6(Gal beta 1}3)GalNAcOH. A minority of the O-glycans are  alpha 1,3 fucosylated that occur as two major species containing the sialyl Lewis x antigen - one species is a disialylated, monofucosylated glycan of formula (I), and the other is a monosialylated, trifucosylated glycan having a polylactosamine backbone of formula (II), wherein R = H, OH, another sugar or an aglycone such as an amino acid.
Patent DE-69636066-D1 (DE)
Inventor: COHEN GARY H
IPC: C12N15/38
Filed: 1996-07-03
Granted: 2006-06-01
Abstract: The present invention provides variant HSV-1 glycoprotein D and HSV-2 glycoprotein D molecules capable of preventing infection of cells by herpes simplex virus types 1 and/or 2. Also provided are novel purified and isolated polynucleotides encoding the variant gD molecules. HSV gD-1 and gD-2 region IV variants or fragments thereof are specifically contemplated by the invention. The presently preferred variant molecule gD-1( DELTA 290-299t) is the product of recombinant expression in Sf9 cells of a fusion protein including the signal peptide of honeybee melittin and Patton strain HSV-1 gD wherein (1) the Patton strain amino acid residues 290 through 299 of the mature gD-1 protein have been replaced with the amino acid residues arginine, lysine, isoleucine and phenylalanine, and (2) Patton strain amino acid residues 308 through 369 have been replaced with five histidine residues. When expressed in Sf9 cells, cleavage of the melittin signal peptide results in the presence of aspartate and proline residues at the amino terminus of the variant molecule. The amino acid sequence of gD-1( DELTA 290-299t) is set out in SEQ ID NO: 2 and the preferred DNA sequence encoding gD-1( DELTA 290-299t) is set out in SEQ ID NO: 1. Administration of gD variant molecules of the invention to mammalian subjects, especially humans, for the purpose of preventing HSV infection and/or ameliorating pathological sequelae of HSV infection is specifically contemplated.
Patent DE-69636500-D1 (DE)
Inventor: TIEDEMANN G
IPC: H04H20/00
Filed: 1996-10-10
Granted: 2006-10-12
Abstract: A communications network and method for over the air service programming a mobile station (2), where the mobile station transmits a service programming request to a communications network, which results in the mobile station (2) being connected to a customer service center (26). Customer service center (26) queries the user of mobile station (2) for information in response to which the customer service center (26) selects a home location register (18) and authentication center (22) within the communication network with which the mobile station (2) is to be associated. Service programming information associated with the mobile station (2) is transferred from the home location register (18) and/or the authentication center (22) into mobile station (2).
Patent DE-69701369-D1 (DE)
Inventor: EBEL BRIAN JOHN
IPC: B42F9/00
Filed: 1997-01-24
Granted: 2000-04-13
Abstract: A bookbinding unit comprises an integral cover body (10) formed by a front cover (12), spine (14) and a back cover (16), an elastic clam (20) in the form of a U-shaped groove mounted to the back cover (14), and a rigid and/or elastically biased slider (30) in the form of a U-shaped groove adapted to be slidably inserted into the clamp (20) to hold upper end edges (22a, 22b) of the clamp (20) leaving space therebetween. An elastic grasping force between both the upper end edges (22a, 22b) of the clamp (20) is set to be sufficient to semi-permanently fix documents (42) inserted and mounted in the clamp (20). In addition, the clamp (20) and the slider (30) are formed by metal or plastics and set to have substantially the same lengths as that of the cover body (10). <IMAGE>
Patent DE-69717670-D1 (DE)
Inventor: WHITELEY MICHAEL
IPC: C09K17/52
Filed: 1997-11-13
Granted: 2003-01-16
Abstract: A method of treating plant biomass material involves treating the material with sesquioxide mineral forming constituents to form protective coatings on surfaces of the material and to alter the bulk physical and chemical properties of the treated material. The material is treated with an aqueous solution of soluble iron and/or aluminum thus improving microbial stability and quality of the materials.
Patent DE-69726135-D1 (DE)
Inventor: KIEFER E
IPC: C07F9/6561
Filed: 1997-04-08
Granted: 2003-12-18
Abstract: Fluorescent chelates of terbium and europium with tri- and tetra-cyclopolyazamacrocyclic compounds are discussed which can be used as fluorescent in vitro or in vivo diagnostic agents. These chelates are tissue specific imaging agents.
Patent DE-69731186-D1 (DE)
Inventor: DEAN F
IPC: H04N7/173
Filed: 1997-02-06
Granted: 2004-11-18
Abstract: The present invention is a method and apparatus for integrating a personal communication system with a cable television plant. A set of radio antenna devices (RAD) are connected to the cable plant. The RADs provide frequency conversion and power control of signal received from the cable plant for wireless transmission to the remote units. The RADs also provide power control and frequency conversion of wireless signals received from the remote units for transmission by the RADs onto the cable plant. In addition to the functions of standard base stations and centralized controller, the CATV base station must also compensate for gain variations in the cable plant. The downstream power control is regulated by a RAD reference signal which can be hidden within the CDMA signal for maximum efficiency. The upstream power control is regulated by an upstream gain reference signal which is individually transmitted by each RAD on the upstream link. The architecture of the present invention lends itself to a great deal of flexibility. Each RAD can operate as either an element of a distributed antenna or a base station sector unto itself. The function of each RAD as distributed antenna or as sector can be remotely programmed from the headend processor. Thus the capacity density of the system can be changed to accommodate the changing traffic density. The flexibility also is important at system deployment. When the system is deploy, the entire system may feed only one sector at the base station thus reducing the start-up cost of implementing a system. As system traffic increases, more resources can simply be added at the headend to provide more capacity.
Patent DE-69731939-D1 (DE)
Inventor: GOUDSMIT JAAP
IPC: C12Q1/6855
Filed: 1997-02-14
Granted: 2005-01-20
Abstract: The invention relates to methods for easily separating single stranded nucleic acid material from double stranded nucleic acid material in a sample containing both. By the right choice of at lease one chaotropic agent, preferably a guanidine salt, at a selected concentration and other suitable conditions such a chelating agents, pH and the like, it is possible to bind double stranded material to a solid phase such as silica particles, whereas single stranded material will not bind under those circumstances. By separating the silica particles from the sample the double stranded nucleic acid material is removed. It can easily be eluted from the silica particles. In a second step the single stranded material may be bound to a solid phase by selecting a different set of conditions. The particles can again be separated from the sample and the single stranded material may now be eluted. For very efficent separations, the process may be repeated. Following the separation of the two kinds of nucleic acid, either kind may be amplified. Methods of amplification are provided which do not need sequence data of the material to be amplified. In these methods a primer will be provided with an amplification motif and a random hybridization motif.
Patent DE-69806608-D1 (DE)
Inventor: SINNESAL DANIEL
IPC: B25B27/02
Filed: 1998-04-20
Granted: 2002-08-22
Abstract: A device for fixing and removing stud seats for boots. The seats are designed to be fitted from above the boot sole and receive the studs screwed from underneath the sole. The device includes a first portion forming a handle having a means for fixing the seats on a first surface and a second portion forming a handle having means for removing the seats from a first surface, the first surface of the first portion capable of being fitted into a second surface of the second portion, and the first surface of the second portion capable of being fitted into a second surface of the first portion.
Patent DE-69808918-D1 (DE)
Inventor: BUNEL CHRISTOPHE
IPC: B29C49/36
Filed: 1998-07-16
Granted: 2002-11-28
Abstract: The invention concerns a method whereby in an installation (1, 2, 3) for making containers (200, 300) by blowing blanks (400), for example thermoplastic preforms, the high pressure fluid derived from degassing a container is re-used and injected (14) into a container previously degassed, for example for cooling it or for thoroughly spraying the inside thereof to solidify the material.
Patent DE-69809827-D1 (DE)
Inventor: PARK NO SANG
IPC: A61P25/16
Filed: 1998-03-27
Granted: 2003-01-16
Abstract: A class of quinolinic sulfide derivatives of formula I are potent and specific antagonists at the strychnine insensitive glycine binding site on the NMDA receptor complex with an pharmacological advantageous profile. They may be useful in treatment or prevention of neurodegenerative disorders. Particularly, the compounds included in the present invention are especially useful for minimizing damage of the central nervous system arising as a consequence of ischemic or hypoxic condition such as stroke, hypoglycemia, cerebral ischemia, cardiac arrest, and physical trauma. They are also useful in prevention of chronic neurodegenerative disorders including epilepsy, Alzheimer's disease, Huntington's disease and Parkinsonism. By virtue of their NMDA receptor antagonist properties, the present compounds may also use as anticonvulsant, analgesic, antidepressant, anxiolytic, and antischizophrenic agent. <CHEM> wherein R1, R2, R3, R4, and R are defined in specification.of t
Patent DE-69813870-D1 (DE)
Inventor: CAMA D
IPC: A61K31/397
Filed: 1998-10-19
Granted: 2003-05-28
Abstract: Compounds of formula (I) are disclosed as well as pharmaceutically acceptable salts thereof. The naphthosultam is substituted with various substituent groups including at least one cationic group -A-Q-L-B. The carbapenems of the invention are effective against susceptible bacterial organisms, including methicillin resistant Staphylococcus aureus (MRSA), methicillin resistant Staphylococcus epidermidis (MRSE), and methicillin resistant coagulase negative Staphylococci (MRCNS).
Patent DE-69818246-D1 (DE)
Inventor: WAGNER J
IPC: A61F2/28
Filed: 1998-04-30
Granted: 2003-10-23
Abstract: Method and apparatus for promoting a spinal fusion between neighboring vertebrae are disclosed. Apparatus may be located within the intervertebral disc space and preferably includes a pair of engaging plates for contacting the vertebrae. An alignment device may be used to alter the vertical height between the engaging plates to customize the apparatus to fit a given patient. In one embodiment, the alignment device includes two turnbuckles and two pairs of cam blocks for adjusting the height between the engaging plates.
Patent DE-69831153-D1 (DE)
Inventor: POLL W
IPC: F16J15/32
Filed: 1998-07-15
Granted: 2005-09-15
Abstract: A two-piece cartridge-type seal for wheel bearings and the like. The seal element contains a radial flange having a seal attached thereto and a mounting flange portion. The wear sleeve portion includes a cylindrical flange receivable over a rotary part, and a radial flange having an extension with an inner surface which engages a part of the seal during installation only. In use, the radial flange of the wear sleeve is engaged by a tool, and this radial flange deflects slightly to push the seal element into a desired position of installation, whereupon, when the tool is removed, the radial flange springs back and creates a slight working clearance between these parts.
Patent DE-69837085-D1 (DE)
Inventor: MCCARTHY A
IPC: C12N5/10
Filed: 1998-04-16
Granted: 2007-03-29
Abstract: Novel CRSP polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length CRSP proteins, the invention further provides isolated CRSP fusion proteins, antigenic peptides and anti-CRSP antibodies. The invention also provides CRSP nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a CRSP gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
Patent DE-69838326-D1 (DE)
Inventor: PENTIKAEINEN JUKKA
IPC: H04W24/02
Filed: 1998-07-22
Granted: 2007-10-11
Abstract: A method for recovering group data between mobile systems, which incorporate at least one first mobile system, at least one second mobile system, and mobile stations, the method comprising the steps of maintaining group data in a first database of the first mobile system, maintaining group data in a database of the second mobile system. In the method, a recovery request is made for recovering the group data, the second mobile system generates one or more virtual attachment requests for the first database of said group, the second mobile system transmits the virtual attachment request to the first database of the first mobile system, in response to the first virtual attachment request, the group data are updated in the first database.
Patent DE-69902264-D1 (DE)
Inventor: MCCONNELL JAMES W
IPC: A47J37/04
Filed: 1999-05-20
Granted: 2002-08-29
Abstract: A staged rotisserie for cooking poultry includes a housing having an inlet end and an outlet end and a plurality of discrete heating stations spaced within the housing between the inlet end and the outlet end. A plurality of poultry spits are moved through the housing, each spit supporting a poultry thereon. An admission mechanism is provided for controlling admission of spits into the housing. An advancement and driving mechanism advances the spits through the housing in sequential fashion and drives the spits in rotation within the housing, and is operative to ensure that each spit resides within the housing for a pre-determined length of time to ensure that the poultry is properly cooked, thereby avoiding undercooking and overcooking.
Patent DE-69903803-D1 (DE)
Inventor: EBERLE C O SCHMALBACH-LUBECA I
IPC: B65D79/00
Filed: 1999-04-28
Granted: 2002-12-12
Abstract: The present invention provides an improved blow molded plastic container that is adapted for hot fill applications. The hot fill container of the present invention comprises a plurality of vacuum panels, having substantially arched upper and lower ends, as opposed to the substantially straight upper and lower ends as described in the related art. The hot fill container of the invention further comprises novel and unique vacuum panel reinforcement means. The vacuum panel reinforcement means are a series of arched ribs. One series of ribs is placed in the label mounting area above the vacuum panels and one series of ribs is placed in the label mounting area below the vacuum panels. The ribs extend noncontinuously around the circumference of the body of the plastic container and are spaced apart from each other by a land area. Each rib is also spaced apart from the vacuum panel and is centered over a land area between vacuum panels. The hot fill bottle of the invention is particularly adapted to minimize the stress placed on the corners of vacuum panels and to resist flexing when the container is filled with a hot liquid.
Patent DE-69906454-D1 (DE)
Inventor: MERRILL JAMES T
IPC: C07C2/66
Filed: 1999-11-16
Granted: 2003-05-08
Abstract: Ethylbenzene is produced by alkylation over a split load of monoclinic silicalite alkylation catalysts having different silica/alumina ratios. A feedstock containing benzene and ethylene is applied to a multi-stage alkylation reaction zone having a plurality of series-connected catalyst beds. At least one catalyst bed contains a first monoclinic silicalite catalyst having a silica/alumina ratio of at least 275. At least one other catalyst bed contains a second monoclinic silicalite catalyst having a silica/alumina ratio of less than about 275. The alkylation reaction zone is operated at temperature and pressure conditions in which the benzene is in a gaseous phase to cause gas-phase alkylation of the aromatic substrate in the presence of the monoclinic silicalite catalysts to produce an alkylation product. The alkylation product is then withdrawn from the reaction zone for separation and recovery. The use of the split load of catalyst allows a higher purity ethylbenzene product to be produced at improved efficiencies than if only one of the catalysts were used by itself.
Patent DE-69906507-D1 (DE)
Inventor: OSBORN WARD
IPC: A61F13/472
Filed: 1999-04-30
Granted: 2003-05-08
Abstract: An absorbent interlabial device worn by female wearers for catamenial purposes, incontinence protection, or both, is disclosed. The absorbent interlabial device has at least one body-contacting surface which comprises a substance that contacts the wearer's body for assisting the interlabial device in staying in place in the desired position in the interlabial space. The substance can be either adhesive or non-adhesive. In embodiments in which the substance is non-adhesive, it may have no initial tack so that it will not stick to the wrong portions of the wearer's body when the device is placed between the labia. Non-adhesive substances include moisture-activated substances which become viscous and develop a tack when contacted by relatively small amounts of moisture.
Patent DE-69907722-D1 (DE)
Inventor: DE MOEL JACOB
IPC: B01D61/16
Filed: 1999-11-12
Granted: 2003-06-12
Abstract: A membrane filtration for removing floating substances and salts from a liquid, uses vertically positioned capillary or tube membranes which are suitable for performing nano or hyper-filtration. Repeatedly and consecutively the following steps are performed: a) a permeate is produced without discharge of concentrate for a predetermined period of time; b) then a gas, for example air, is guided along side the membrane, at least almost without discharge of permeate and without discharge of concentrate; c) and finally a concentrate is discharged without discharge of permeate. During step a) and step c) use can be made of a combined supply of liquid and gas. An apparatus for performing this method is described as well.
Patent DE-69910101-D1 (DE)
Inventor: SEBASTIAN ALICE
IPC: C07D307/77
Filed: 1999-02-24
Granted: 2003-09-11
Abstract: A novel process for the preparation of codeinone and analogues thereof comprising the oxidation of a compound of formula, <CHEM>     or a salt thereof, wherein R<1> is lower alkyl or a group <CHEM> wherein R<4> is lower alkyl, lower alkyl substituted by halogen or phenyl, phenyl or substituted phenyl; and R<2> is lower alkyl, allyl or lower alkyl substituted by cycloalkyl, characterised in that the oxidation is carried out in an acidic environment is disclosed.
Patent DE-69914919-D1 (DE)
Inventor: HUHTELIN TAISTO
IPC: D21F1/06
Filed: 1999-06-04
Granted: 2004-03-25
Abstract: Method for regulating the surface level and the consistency in a stock chest for metering of a component stock. Stock is fed as an outward flow out of the bottom portion of a storage tower by a first pump into the stock chest. Into this outward flow, a first dilution water flow is passed in order to regulate the consistency of the stock fed into the stock chest to a-desired level. The stock is fed as a metering flow from the stock chest by a second pump into the short circulation of the paper or board machine. The surface level in the stock chest is maintained constant by an overflow passed from the stock chest (20) into a pumping tank. From the pumping tank, stock is fed as a return flow by a third pump into the bottom portion of the storage tower. A second dilution water flow is passed into this return flow to thereby regulate the consistency in the bottom portion of the storage tower to a desired level. The stock is stirred in the bottom portion of the storage tower and in the stock chest in order to provide a uniform consistency.
Patent DE-69927306-D1 (DE)
Inventor: MASATOSHI INUKAI
IPC: C12P/
Filed: 1999-07-09
Granted: 2005-10-20
Abstract: Compounds of formulae (XI), (XII), (XIV), (XV) and (XVI), as well as amide derivatives of compounds of formula (XIII), described herein, can be obtained from the cultivation products of a strain of micro-organism of the genus Streptomyces. The compounds are useful as medicaments in the treatment and prevention of bacterial infections.
Patent DE-69927323-D1 (DE)
Inventor: PINTAURO ARTHUR C
IPC: F16K31/10
Filed: 1999-07-13
Granted: 2006-02-02
Abstract: A continuously variable electrical actuator (22) is rotationally coupled to and thermal isolated from a butterfly valve (24). The butterfly valve (24) may be used to modulate high temperature exhaust gas flow through an engine turbocharger (200). An electrical actuator (42) provides a continuously variable output to an output shaft (44). The butterfly valve (24) has its rotary position controlled by an input shaft (34). The input shaft (34) and output shaft (44) are rotationally coupled through minimum contact points to reduce heat transfer. The connection between input and output shafts (34, 44) also minimizes vibration transfer therebetween. A coupling tube (58) coaxially interposed between the input and output shafts (34, 44) provides a thermal block to further reduce heat transfer. The input and output shafts (34, 44) are rotationally coupled to the intermediate shaft by torsion spring mechanisms (68, 66) to allow a limited range of axial translation for the input shaft (34). The torsion spring mechanisms (68, 66) are preloaded to prevent rotational hysteresis in the butterfly valve. <IMAGE>
Patent DE-69930778-D1 (DE)
Inventor: ROEMISCH JUERGEN DR
IPC: A61K38/48
Filed: 1999-04-08
Granted: 2006-05-24
Abstract: A protease for activating the blood clotting factor VII is described, which     a) is inhibited by the presence of aprotinin, b) is increased in its activity by calcium ions and/or heparin or heparin-related substances, and c) in SDS-PAGE, on subsequent staining in the non-reduced state, has one or more bands in the molecular weight range from 50 to 75 kDa and kDa in the reduced state has a band at 40 to 55 kDa and one or more bands in the molecular weight range from 10 to 35 kDa.   The proenzyme of this protease is also characterized. Moreover, a process for obtaining this protease and its use in hemorrhage prophylaxis or hemostasis is described. A stabilized factor V and a stabilized factor VIII preparation are furthermore described which are free of the inactive factor VIII fragments formed by proteolytic degradation as a result of the inhibition or the removal of the protease activating the blood clotting factor VII.