baber/WOPTO huggingface dataset:
Patent NZ-505927-A (NZ)
Title: Cyclobutene-1,2-dione derivatives for use in the inhibition of an ileal bile acid transporter
Inventor: KONO KEITA
IPC: A61K31/4409
Filed: 2000-07-21
Abstract: A compound of the Formula (I) for use in the manufacture of medicaments for treating hypercholesterolaemia and for inhibition of an ileal bile acid transporter. Wherein; R1 represents a cycloalkyl group, an aryl group, a heterocyclic group, a cycloalkyl group substituted by at least one of substituents a and b, an aryl group substituted by at least one of substituents a and b, or a heterocyclic group substituted by at least one of substituents a and b; R2 represents a cycloalkyl group, an aryl group, a heterocyclic group, a cycloalkyl group substituted by at least one of substituents a, an aryl group substituted by at least one of substituents a, or a heterocyclic group substituted by at least one of substituents a; R3 and R4 are the same as or different from each other and each represents a hydrogen atom or one of substituents a; A represents a group of Formula (A-1); wherein R5 represents a hydrogen atom, a hydroxy group or a lower alkyl group, R6 represents a hydroxy group, a lower alkoxy group, a lower alkylthio group or an amine residue, X and Y are the same as or different from each other and each represents an oxygen atom or a sulphur atom, and Z represents a direct single bond between the nitrogen atom shown and the benzene ring shown in Formula (I), or an alkylene group having from 1 to 6 carbon atoms; G represents a single bond, an alkylene group having from 1 to 6 carbon atoms or an alkylene group having from 1 to 6 carbon atoms and substituted by at least one of substituents g; The broken line represents a single or double bond; When the broken line represents a double bond; D represents a carbon atom; E represents an =N-O- group; When the broken line represents a single bond; D represents a CH group or a nitrogen atom, and E represents an oxygen atom, a sulphur atom, an -NH- group or a -CO- group; The substituents a are selected from halogen atoms, hydroxy groups, cyano groups, nitro groups, lower alkyl groups, lower halo alkyl groups, lower alkoxy groups, lower alkylthio groups, amino groups, lower mono-alkyl amino groups and di(lower alkyl)amino groups. The substituents b are selected from carboxy groups, lower alkoxycarbonyl groups, carbamoyl groups, lower monoalkylcarbamoyl groups, di(lower alkyl)carbamoyl groups, nitro groups, cycloalkyl groups, aryl groups, aryloxy groups, aralkyloxy groups, arylthio groups and cycloalkyl, aryl, aryloxy, aralkyloxy and arylthio groups each substituted by at least one of substituents a; The substituents g are selected from hydroxy groups, oxo groups, cycloalkyl groups, aryl groups, heterocyclic groups, cycloalkyl groups substituted by at least one of substituents a and b, aryl groups substituted by at least one of substituents a and b, and heterocyclic groups substituted by at least one of substituents a and b.
Patent NZ-508005-A (NZ)
Title: Amino acid amidinohydrazones, alkoxyguanidines and aminoguanidines useful as serine protease inhibitors
Inventor: LU TIANBAO
IPC: A61P7/02
Filed: 1999-04-22
Abstract: An amino acid amidinohydrazone, alkoxyguanidine or aminoguanidine derivative or a solvate, hydrate or pharmaceutically acceptable salt thereof has the formula I, including stereoisomers wherein: A' is a structural fragment of formula IIa, IIb, Ilc, Ild, IIe, IIf or IIg; A2 is a structural fragment of Formula IlIa, IIIb or IIIc; R7 is hydrogen, alkyl, aralkyl, aryl, hydroxyalkyl, aminoalkyl, monoalkylaminoalkyl, dialkylaminoalkyl, carboxyalkyl, hydroxy, alkoxy, aralkoxy, aryloxy, heteroaryloxy, or mono- or di-alkylamino, provided that n is other than zero when R7 is hydroxy, alkoxy, aralkoxy, aryloxy, heteroaryloxy, or mono-or di-alkylamino; R8, R9 and R10 are each independently one of hydrogen, alkyl, aralkyl, aryl, hydroxyalkyl, aminoalkyl, monoalkylaminoalkyl, dialkylaminoalkyl or carboxyalkyl; or R7 and R8 are taken together to form -(CH2)i and i is 0 to 2, while R9 and R10 are defined as above; or R7 and R10 are taken together to form- (CH2)jÆ- and jÆ is 0 to 8, while R8 and R9 are defined as above; or R8 and R9 are taken together to form -(CH2)h- and h is 2-8 while R7 and R8 are defined as above; R18 is of hydrogen, alkyl, alkenyl, alkynyl, aralkyl, aryl, hydroxyalkyl, aminoalkyl, monoalkylamino alkyl, dialkylamino alkyl or carboxyalkyl or R18 and R10 taken together to form -(CH2)wÆ- and wÆ is 1-5; X is oxygen, NR19 or CH=NR19, where the nitrogen of C H=N R19 is attached to the nitrogen of NR18; Ra, Rb and Rc are independently hydrogen, alkyl, hydroxy, alkoxy, aryloxy, aralkoxy, alkoxycarbonyloxy, cyano or -CO2Rw; n is from 0 to 8; m is from 0 to 4 and R1 to R6, R19, R21 to R23, Rw, Y, d, e, j, k, and q are as defined in the specification. The compounds are useful for inhibiting a serine protease and for inhibiting loss of blood platelets, inhibiting formation of blood platelet aggregates, inhibiting formation of fibrin, inhibiting thrombus formation, and inhibiting embolus formation
Patent NZ-508043-A (NZ)
Title: Method for stereochemically controlled production of isomerically pure substituted pyrrolidine or piperidine compunds
Inventor: REGGELIN MICHAEL
IPC: C07C381/10
Filed: 1999-05-10
Abstract: A process for stereochemically controlled production of azacyclic compounds of formula (I), whereby the substituents have the meaning as described in the specification, the intermediate products of this process and the resultant azacyclenes are disclosed.
Patent NZ-510067-A (NZ)
Title: Method for manufacturing a smooth plastic carrier surface for chemical or biochemical assays
Inventor: PUIJK WOUTER CORNELIS
IPC: G01N31/22
Filed: 1999-07-21
Abstract: Method for manufacturing a preparation carrier, in particular suitable for use in chemical and biochemical research is disclosed, wherein: a plastic layer is provided on at least one surface of a carrier base; the plastic layer is treated thermally and/or chemically, such that the surface roughness of the side of the plastic that faces the carrier base is reduced, while it does not adhere to the carrier base; whereupon the plastic is removed from the carrier base, with the released, relatively smooth surface of the plastic forming a carrier surface.
Patent NZ-515048-A (NZ)
Title: 1,5-benzodiazepine derivatives
Inventor: COLCLOUGH DAVID
IPC: A61P1/16
Filed: 2000-05-04
Abstract: Enantiomerically enriched 3-{3-[1-(isopropyl-phenyl-carbamoylmethyl)-2,4- dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-3-yl]-ureido}benzoic acid, or a pharmaceutically acceptable salt or solvate thereof where the (+)-enantiomer is at least 90% of the compound is useful for treating CCK-A mediated diseases.
Patent NZ-517015-A (NZ)
Title: A convertible hat
Inventor: CONVERY RICHARD
IPC: A42B1/12
Filed: 2000-07-10
Abstract: A convertible hat including a crown and a brim that can be converted between a conventional hat to a skullcap type configuration, such as a swimming cap. The brim is hingedly connected to the lower peripheral edge of the crown and protruding outwardly from the crown in an operative shading condition. The brim is retractable from the operative condition such that the brim substantially conforms to at least a portion of the outer surface of the crown.
Patent NZ-518753-A (NZ)
Title: Novel androgens
Inventor: VAN DER LOUW JAAP
IPC: A61K31/575
Filed: 2000-11-29
Abstract: Described are steroid compounds having a cyclopropene ring, of formula (I), for which the substituents are described herein. The compounds are used in the manufacture of medicaments having androgenic activity.
Patent NZ-521205-A (NZ)
Title: KCNB: a novel potassium channel protein and methods for treating cancer
Inventor: MU DAVID
IPC: C07K14/705
Filed: 2001-03-02
Abstract: Described is a nucleic acid sequence encodings a potassium channel polypeptide. Also disclosed are antibodies, methods of identifying compounds that modulate the activity of the polypeptide and methods of detecting cancer cells in a sample. Inhibitors of the polypeptide can be used in the manufacture of a medicament for inhibiting proliferation of cancer cells.
Patent NZ-522182-A (NZ)
Title: Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis
Inventor: SCHIMMEL PAUL
IPC: C07H21/04
Filed: 2001-03-21
Abstract: Compositions comprising tRNA synthetase polypeptides useful for regulating angiogenesis, as well as nucleic acids encoding such tRNA synthetase polypeptides are described. Methods of making and using such compositions are also disclosed.
Patent NZ-523081-A (NZ)
Title: Air freshner dispenser with offset electrical plug to prevent user from plugging in further devices that could come into contact with the vapour
Inventor: WEFLER MARK E
IPC: A61L9/03
Filed: 2001-06-08
Abstract: A dispenser (1) of active materials, such as an air freshener or insecticides, comprises an "offset" adapter (6) for plugging into a vertically oriented duplex wall outlet, whereby the effective position of the dispenser's electrical plug (7) is lowered sufficiently so as to fully expose and make available the lower receptacle when plugged into the upper receptacle. Further, the dispenser blocks and prevents the use of the upper receptacle when plugged into the lower receptacle. In this manner, the consumer is prevented from plugging another appliance or device into a receptacle that may subject it to contact by vapor being dispensed by the dispenser.
Patent NZ-523958-A (NZ)
Title: 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derviative as anti-inflammatory agents
Inventor: BIGGADIKE KEITH
IPC: C07J33/00
Filed: 2001-08-03
Abstract: Compounds of formula (I) are disclosed, wherein: R1 is alkyl or haloalkyl, R2 is -C(=O)-aryl or -C(=O)-heteroaryl, R3 is H, methyl or methylene, R4 and R5 are independently H or halogen, and the dotted line represents and optional double bond. The compounds are used in the manufacture of medicaments for the treatment of inflammatory and/or allergic conditions.
Patent NZ-525716-A (NZ)
Title: Domestic oven heating element with slidable terminal contacts for fine positioning adjustment
Inventor: WILSON RON
IPC: F24C7/06
Filed: 2001-11-08
Abstract: The terminals of oven heating coil element 200 slide against rails 350 that are connected to the power input terminals for the heating element so that the coil can be slid up or down to be mounted centrally around the oven fan despite that in ovens of different make and model the height between the axis of the fan and the power input terminals will be different.
Patent NZ-527764-A (NZ)
Title: Combination comprising a signal transduction inhibitor and an epothilone derivative
Inventor: BRANDT RALF
IPC: A61P43/00
Filed: 2002-02-26
Abstract: Disclosed is a combination which comprises (a) a signal transduction inhibitor selected from a PDGF (platelet-derived growth factor) receptor tyrosine kinase inhibitor and an active ingredient which decreases the activity of the epidermal growth factor (EGF) and (b) an epothilone derivative of formula (I), wherein A represents O or NRN, wherein RN is hydrogen or lower alkyl, R is hydrogen or lower alkyl, and Z is O or a bond. Further disclosed is a medicament comprising the combination, and the use of the medicament for the delay of progression or treatment of a proliferative disease.
Patent NZ-531766-A (NZ)
Title: Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
Inventor: MORO DANIEL G
IPC: A61P17/02
Filed: 2002-08-16
Abstract: A water-erodible coating layer for controlling the residence time of a water-soluble thin-film device that is adhered to a moist surface of a body tissue is disclose, wherein the water-erodible coating layer comprises at least one hydrophobic polymer (such as ethyl cellulose polymers, methyl cellulose polymers, anionic, cationic or neutral methacrylate polymers, acrylate co-polymers or a combination thereof) and at least one water-soluble polymer (such as polyvinyl pyrrolidone, hydroxypropyl methyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose or polyvinyl alcohol), wherein the ratio of the hydrophobic polymer(s) to the water-soluble polymer(s) is from 1:1 to 9:1 by weight. A layered pharmaceutical delivery device for the administration of pharmaceuticals or other active compounds to mucosal surfaces is also disclosed. The device may also be used by itself without the incorporation of a therapeutic. The device consists of a water-soluble adhesive layer, a non-adhesive, bioerodible backing layer and one or more pharmaceuticals if desired in either or both layers. Upon application, the device adheres to the mucosal surface, providing protection to the treatment site and localized drug delivery. The "Residence Time", the length of time the device remains on the mucosal surface before complete erosion, can be easily regulated by modifications of the backing layer.
Patent NZ-533885-A (NZ)
Title: Mesh container, system using mesh containers, and method for making mesh containers
Inventor: CHENG HSI-MING
IPC: B65D21/032
Filed: 2002-12-03
Abstract: A container 14B formed from three pieces of mesh material is disclosed. A first piece of mesh is bent to form a bottom wall 56 and a first pair of sidewalls 62. A second piece of material forms a third sidewall 58 joined to the bottom wall and a third piece of mesh material forms a fourth sidewall 60. The third and fourth sidewalls are each bent to form a central portion between a pair of sidewall corners 64. When the pieces are joined together, a basket portion with an upwardly extending opening is formed. The basket portion may further include a runner portion that may be a separate rail (54) connected to the basket portion, thus forming a drawer.
Patent NZ-533945-A (NZ)
Title: Smartcard system
Inventor: BRESLIN ANTHONY
IPC: G06F21/77
Filed: 2002-12-09
Abstract: A machine readable medium carries operating software for use in a system which comprises the programmable device carrying at least one on-device file and/or application and an interface device for interfacing with the or each programmable device. The interface device is provided with at least one one-off device file and/or application; the operating software. The operating software enables, in use, the on-device and off-device files and/or applications to interface with one another and includes at least one file formatted in a web (Internet) standard language for self-describing messages, preferably XML. This file contains at least some of the file system and commands for accessing the file system which allow the on-device and off-device files and/or applications to interface. The interface device may be provided with at least one upgrade file in, for example, XML which contains an upgraded version of at least one on-device file and/or application and includes means for comparing the version of the on-device file or application on a particular programmable device with that in the upgrade file, upgrading the on-device file or application if the version on that device is earlier than that in the upgrade file. The interface device or the programmable device may, further, be provided with a file in web standard language which contains at least one configurable Security Environment. The system or device may include a plurality of files formatted in web standard language for self-describing messages, each of those files including a data model ('virtual card') corresponding to one of a plurality of different programmable devices, for example, smart cards of different kinds. The system may include means for configuring at least one of those virtual cards for downloading on to a memory-bearing programmable device. The system may further include at least one file in web standard language for self-describing messages capable of generating at least one APDU which, when run on a smart card, modifies or updates existing files or file structures.
Patent NZ-538142-A (NZ)
Title: Marine anchor including a double shank and a pair of fluke having a forwardly pointing tip
Inventor: SAUNIER BARRY
IPC: B63B21/44
Filed: 2005-02-09
Abstract: Disclosed is a marine anchor (10) comprising a double shank (12) and a fluke (16) with a pair of fluke portions (18) on either side of a central plane of symmetry (20) of the anchor, each fluke portion including a forwardly pointing tip (22) and at least a side part (24) of each fluke portion being downwardly inclined laterally so as to form a concave region on the underside of the fluke.
Patent NZ-538480-A (NZ)
Title: Lithium-nickel-cobalt-manganese containing composite oxide, material for positive electrode active material for lithium secondary battery, and methods for producing these
Inventor: SUHARA MANABU
IPC: H01M4/525
Filed: 2004-03-22
Abstract: A method for manufacturing a lithium-nickel-cobalt-manganese-containing composite oxide represented by a general formula, LipNixMn1-x-yCoyO2-qFq (where 0.98<=p<=1.07, 0.3<=x<=0.5, 0.1<=y<=0.38, and 0<=q<=0.05) is disclosed, wherein the method comprises: a step for synthesizing coagulated particles of a nickel-cobalt-manganese composite hydroxide wherein primary particles obtained by precipitating the nickel-cobalt-manganese composite hydroxide are coagulated to form secondary particles, by supplying an aqueous solution of a nickel-cobalt-manganese salt, an aqueous solution of an alkali-metal hydroxide and an ammonium-ion donor continuously or intermittently to a reaction system, and making the reaction proceed in the state wherein the temperature of said reaction system is substantially constant within a range between 30 and 70 DEG C, and pH is maintained at a substantially constant value within a range between 10 and 13; a step for synthesizing coagulated particles of a nickel-cobalt-manganese composite oxyhydroxide by making an oxidant act on said coagulated composite hydroxide particles; and a step for dry-blending at least said coagulated composite oxyhydroxide particles and a lithium salt, and firing the mixture in an oxygen-containing atmosphere.
Patent NZ-541475-A (NZ)
Title: Wireless medical data communication system and method
Inventor: SIMPSON THOMAS L
IPC: G16H10/60
Filed: 2004-01-30
Abstract: A system for checking the integrity of a wireless communication link in a healthcare facility is disclosed. A wireless device (118) receives information representing a signal generated by a medical treatment device (120). Software on the wireless device indicates loss of the wireless communication link if a time-out output occurs.
Patent NZ-543240-A (NZ)
Title: Cutting insert for turning
Inventor: LOF RONNIE
IPC: B23B27/14
Filed: 2004-05-04
Abstract: A turning insert is disclosed that exhibits reduced abrasive jet wear of the cutting corner when used in chip removing machining. The insert has a top cutting surface (1) with at least one corner area (7) which defines a nose angle in the range of 30-85 degrees, and a bottom surface. A side surface (3) extends between the top cutting surface and the bottom surface along the perimeter of the surfaces. The side surface includes a clearance surface portion (10) that is bevelled with respect to two side surface portions disposed on opposite sides of the clearance surface portion. The intersection of the corner area and the clearance surface portion defines a bevelled edge, and a bisector of the nose angle intersects the bevelled edge at a midpoint thereof at a right angle.
Patent NZ-545565-A (NZ)
Title: Formulation of a mixture of Free-B-Ring flavonoids and flavans for use in the prevention and treatment of cognitive decline and age-related memory impairments
Inventor: JIA QI
IPC: A61K31/7048
Filed: 2004-09-01
Abstract: Disclosed is the use of a mixture of at least one Free-B-ring flavonoid and at least one flavan for the preparation of a pharmaceutical composition for preventing and treating cycloxygenase (COX) and lipoxygenase (LOX) mediated diseases, conditions related to neuronal and cognitive function, inhibiting expression of pro-inflammatory cytokines and preventing reactive oxygen species generation and augmenting antioxidant defences in the brain wherein said mixture comprises baicalin isolated from a plant or plants within the Scutellaria genus of plants and catechin, isolated from a plant or plants within the Acacia genus of plants. Reference has been directed by the Commissioner under section 16 to patent specification 535988.
Patent NZ-545661-A (NZ)
Title: Novel use of antisecretory factor
Inventor: HANSSON HANS-ARNE
IPC: A23L33/00
Filed: 2004-09-24
Abstract: Discloses is the use of an antisecretory protein or an oligo- or polypeptide or functional derivatives thereof comprising an amino acid sequence of Formula I: X1-V-C-X2-X3-K-X4-R-X5 (Formula I) wherein X1 is I, amino acids nos. 1-35 of SEQ ID NO:2, or is absent X2 is H, R or K X3 is S or L X4 is T or A X5 is amino acids nos. 43-46, 43-51, 43-80 or 43-163 of SEQ ID NO:2, or is absent, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment and/or prevention of a condition associated with or characterised by a pathological loss and/or gain and/or rescue of nervous tissue. Also disclosed is the use of antisecretory protein inducing foods and egg yolk with a high level of antisecretory protein for the treatment or prevention of conditions associated with loss, gain or rescue of neuronal tissue. Antisecretory protein is also useful in the in vitro propagation of isolated cells.
Patent NZ-550052-A (NZ)
Title: Pharmaceutical composition comprising a salt of enantiomerically pure mirtazapine
Inventor: MOOLENAAR SYTSKE HYKE
IPC: A61K31/55
Filed: 2005-04-19
Abstract: Disclosed is a pharmaceutical formulation which comprises an enantiomerically purified form of mirtazapine (particularly the S-enantiomer) as a pharmaceutically suitable, non-sublimating and solid salt, wherein the salt is of maleic acid or of methanesulfonic acid. Also disclosed is S-mirtazapine maleate, S-mirtazapine methanesulfonate, S-mirtazapine fumarate hydrate and S-mirtazapine bromide monohydrate.
Patent NZ-552251-A (NZ)
Title: A method of encrypting and transferring data between a sender and a receiver using a network
Inventor: ALCULUMBRE MICHAEL
IPC: H04L9/08
Filed: 2005-04-18
Abstract: A method of encrypting and transferring data between a sender and a receiver using a network, the method comprising the steps of:- (a) a server, receiving from the sender, an identifier of the receiver; (b) establishing a transfer specific encryption key specific to the transfer; (c) encrypting the data using the transfer specific encryption key; (d) the server accessing receiver specific information according to the received identifier of the receiver and encrypting, with the receiver specific information, the transfer specific encryption key; (e) transferring the encrypted data and the encrypted transfer specific encryption key over the network for receipt by the receiver; (f) the server, receiving from the receiver, the encrypted transfer specific encryption key; (g) the server accessing the receiver specific information to decrypt the encrypted transfer specific encryption key; and (h) decrypting the encrypted data using the decrypted transfer specific encryption key.