baber/WOPTO huggingface dataset:
Patent NZ-250842-A (NZ)
Title: Resolution of a racemic mixture of nucleoside enantiomers such as 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane (ftc)
Inventor: LIOTTA DENNIS C
IPC: A61K31/506
Filed: 1992-02-17
Abstract: Enantiomerically enriched cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolane-5-yl)-(1H)-pyrimidin-2-one, derivatives and pharmaceutical compositions thereof.
Patent NZ-264516-A (NZ)
Title: Benzodiazepine and benzothiazepine derivatives and analogues; medicaments
Inventor: YUKIMASA HIDEFUMI
IPC: C07D417/06
Filed: 1994-09-22
Abstract: Disclosed is a squalene synthetase inhibitor which comprises the compound represented by the formulawherein R₁ is hydrogen or an optionally substituted hydrocarbon group; R₂ is hydrogen, an optionally substituted alkyl group, an optionally substituted phenyl group or an optionally substituted aromatic heterocyclic ring group; X' is a substituent comprising an optionally esterified carboxyl group, an optionally substituted carbamoyl group, an optionally substituted hydroxyl group, an optionally substituted amino group or an optionally substituted heterocyclic radical having a protonizable hydrogen; Ring A is an optionally substituted benzene ring or an optionally substituted aromatic heterocyclic ring; Ring J' is a 7- to 8-membered heterocyclic ring containing at most three ring constituting hetero atoms; D is C or N; the Ring J' optionally having, besides R₁, R₂ and X', a further substituent; provided that the condensed ring composed of Ring A and ring J' is not a 2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepine ring, or a pharmaceutically acceptable salt thereof, and which is useful for the prophylaxis or therapy of hypercholesteremia or coronary sclerosis of mammals.
Patent NZ-290744-A (NZ)
Title: Moving graphic display: avoids vertical black bands in image
Inventor: SALA OSCAR GOTLIEB
IPC: G09G3/20
Filed: 1995-08-11
Abstract: PCT No. PCT/AU95/00491 Sec. 371 Date Feb. 11, 1997 Sec. 102(e) Date Feb. 11, 1997 PCT Filed Aug. 11, 1995 PCT Pub. No. WO96/05587 PCT Pub. Date Feb. 22, 1996An improved display system which is able to display both static and moving graphics on a reduced number of pixels. The display system relies upon the beta apparent movement effect to "fill in" the blank spaces between active pixels to give the appearance of supporting an image which does not in fact exist. The display system can display moving graphics at high resolution and static graphics at low resolution.
Patent NZ-321135-A (NZ)
Title: Cephalosporin antibiotics
Inventor: CHO IN-SEOP
IPC: A61P31/04
Filed: 1996-10-11
Abstract: The present invention includes (7R)-7-(acylamino)-3-(arylthio)-3-cephem-4-carboxylic acids (formula I); Wherein: R1 is selected from the group -NHC(O)ZR3, -NR4R5 and 1,3 dithiolane. Z is selected from -(CH2(X)m-, -C(NOR6)-, -CH(OR7)-, -C(CHCO2R8) and -CH(NR9R10); X is selected from oxygen and sulphur m is selected from the group 0 or 1. The remaining constituents are as filed in the specification. The invention also includes the pharmacologically acceptable salts of said carboxylic acids which exhibit antibiotic activity against a wide spectrum of organisms including organisms which are resistant to 'beta'-lactam antibiotics -such as methicillin, vancomycin or ampicillin resistant bacteria- and are useful as antibacterial agents. The invention also relates to novel intermediates useful for making the novel compounds of the present invention and to novel methods for producing the novel compounds and intermediate compounds.  Divisional filed as 500512
Patent NZ-329766-A (NZ)
Title: Use of isothiazolidin-3-one-1,1-dioxide and 3-oxo-1,2,5-thiadiazolidine-1,1-dioxide derivatives for reducing the activity of serine proteases
Inventor: GROUTAS WILLIAM C
IPC: C07D285/10
Filed: 1998-02-16
Abstract: Isothiazolidin-3-one-1,1 dioxide, 3-oxo-1,2,5-thiadiazolidine-1,1,-dioxide and derivatives thereof, reduce or inhibit the activity of serine proteases. Such compounds are useful as anti-inflammatory and anti-metastatic agents.
Patent NZ-335579-A (NZ)
Title: Method and composition for controlling marsupial pests comprising calcium homeostasis disruption agent and a stress inducing agent
Inventor: COOK CHRISTIAN JOHN
IPC: A01N59/08
Filed: 1999-05-04
Abstract: The method to control marsupial pests comprises stressing the marsupial and disrupting calcium homeostasis in the marsupial.  The stressing step may by effected by activating the GABA receptors in the marsupial, and may be achieved by use of a chemical agent or by physically stressing the pest using noise or lights.  Calcium homeostasis may be disrupted with a chemical agent, such as cholecalciferol or a salt. The bait composition for controlling pests comprises a calcium homeostasis-disrupting agent; and a stress-inducing chemical agent selected from GABA receptor activating substances, catecholamine and glucocorticoids.
Patent NZ-501696-A (NZ)
Title: Method for large-scale production of sodium and ammonium salts of di(uridine 5')-tetraphosphate
Inventor: PENDERGAST WILLIAM
IPC: C07H21/00
Filed: 1998-07-24
Abstract: The compounds of formula I, wherein X is selected from Na, NH4 and H, (provided that all X groups are not H) may be used in medicaments for treating chronic obstructive pulmonary diseases, sinusitis, otitis media or nasolacrimal duct obstruction, dry eye, retinal detachment, female infertility or vaginal irritation due to vaginal dryness and for facilitating sputum induction and expectoration. The compounds of formula I may be prepared by; a) dissolving uridine, UMP, UDP or UTP in a polar, aprotic organic solvent and a hydrophobic amine; b) phosphorylating with a phosphorylating agent of Formulas IVa-b and/or activating a phosphate group with an activating agent of Formulas IIIa-c; and c) purification by ion exchange chromatography of the compounds of Formula I. In Formula IIIa: Carbodiimide R1 and R2 are independently selected from the group consisting of C1-C8 alkyl, cycloalkyl and aryl, each of which may be optionally substituted with hydroxy or amino groups. In Formula IIIb: Activated Carbonvl X is independently selected from the group consisting of imidazole, tetrazole and halogen. In Formula IIIc: Activated Phosphorus X is halogen and R1 and R2 are each independently selected from the group consisting of C1-C8 alkyl, cycloalkyl, C1-C8 alkoxy, C1-C8 cycloalkoxy, aryl and aryloxy, each of which may be optionally substituted with hydroxy, amino, alkoxy or halogen groups. In Formula IVa: Monophosphorvlating Agents X is halogen. In Formula IVb: Diphosphorylating Agents X is selected from the group consisting of oxygen, hydroxy and halogen.
Patent NZ-501816-A (NZ)
Title: Ring member, for mounting a film roll carriage and dispensing assembly thereon, comprising an annular ring and a reinforcing ring
Inventor: TURFAN FARUK M
IPC: B65B35/00
Filed: 1999-12-15
Abstract: A film carriage support ring having an annular ring and an annular reinforcing ring welded to the external peripheral portion of the annular ring member is described. The annular ring comprises a tubular stock, having a rectangular or square-shaped cross-sectional configuration, which is bent into the annular ring and the free end portions are welded together. In this manner, excessive waste of material in forming conventional rings, wherein such conventional ring are cut out from square plates, is eliminated. Segmentally-configured gusset plate members are welded to diametrically opposite internal peripheral portions of the annular ring to support a film roll carriage and dispensing assembly and a counterbalancing mechanism.
Patent NZ-504028-A (NZ)
Title: Method for producing multi-layer resin molded article by heat molding a multi-layer thermoplastic resin plate comprising a first surface and a second surface
Inventor: OGURA KOJI
IPC: B32B27/30
Filed: 2000-04-14
Abstract: A method for producing a multi-layer thermoplastic resin molded article having almost no drug line by thermoforming is provided. A method for producing a multi-layer thermoplastic resin molded article by thermoforming a multi-layer thermoplastic resin plate (3) comprising a first surface layer (1) and a second surface layer (2) in which the dynamic modulus(G'2) of the second surface layer (2) is less than 1x105 Pa at temperatures at which the dynamic modulus(G'1) of the first surface layer (1) is not more than 5x105 Pa, wherein the first surface layer (1) and the second surface layer (2) of the multi-layer thermoplastic resin plate (3) are heated and thermoformed at different temperatures so that the ratio (G'1/G'2) of the dynamic modulus (G'1) of the first surface layer (1) to the dynamic modulus(G'2) of the second surface layer (2) is not less than 0.35 and less than 2.8.
Patent NZ-504503-A (NZ)
Title: Oxazolidinone derivatives and pharmaceutical use as antimicrobial agents
Inventor: HESTER JACKSON B
IPC: C07D263/00
Filed: 1998-10-30
Abstract: Use of oxazolidinone compounds of formula (I) to treat human and veterinary microbial infections, including gram positive aerobic organisms, gram negative organisms and anaerobic organisms.
Patent NZ-506103-A (NZ)
Title: Saddle for bicycles having two seats where each seat has a first and second cushions the first of which has a projection engaging a cavity in the second cushion
Inventor: BAVARESCO ROBERTO JOSE
IPC: B62J1/08
Filed: 1999-02-18
Abstract: A saddle (1) for bicycles including two separate seats (2, 3) supported by a supporting unit (4) fixed to the bicycle frame. Each one of said seats (2, 3) includes at least a first part (2', 3'), fixed with respect to said supporting unit (4) and at least a second part (2'', 3''), movable with respect to said first part (2', 3'). Said second part (2'', 3'') is revolvingly connected to a gudgeon (10, 11) defining an axis (10a, 11a) substantially horizontal placed substantially orthogonally to the advancement direction (6) of the bicycle
Patent NZ-508577-A (NZ)
Title: Methods and apparatus for dynamic smartcard synchronization and personalization
Inventor: HOHLE WILLIAM
IPC: G06Q20/40
Filed: 1999-05-04
Abstract: A system generally for personalizing and synchronizing smartcard data in the context of a distributed transaction system is disclosed. A dynamic smartcard synchronization system comprises access points configured to initiate a transaction in conjunction with a smartcard, an enterprise data collection unit, and a card object database update system. An exemplary dynamic synchronization system (DSS) preferably comprises various smartcard access points, a secure support client server, a card object database update system (CODUS), one or more enterprise data synchronization interfaces (EDSI), an update logic system, one or more enterprise data collection units (EDCUs), and one or more smartcard access points configured to interoperably accept and interface with smartcards. In an exemplary embodiment, DSS comprises a personalization system and an account maintenance system configured to communicate with CODUS. Personalization of multi-function smartcards is accomplished using a security server configured to generate and/or retrieve cryptographic key information from multiple enterprise key systems during the final phase of the smartcard issuance process
Patent NZ-509593-A (NZ)
Title: Compressed compositions comprising clarified xanthan gum
Inventor: DIXEY MAUREEN
IPC: A61K9/22
Filed: 1999-07-28
Abstract: A solid sustained release pharmaceutical composition comprising a compressed mixture of a pharmacologically active ingredient and a sustained release carrier comprising xanthan gum characterised in that the xanthan gum is capable of dissolving in water at a concentration of 1 part by weight xanthan gum to 100 parts by weight water to form a solution having a transmittance (600 nm) of greater than 50 %. The clarified xanthan gum has an improved reproducibility in drug dissolution.
Patent NZ-510286-A (NZ)
Title: Nut with malformed thread portion, for use with mine roof bolt
Inventor: CALANDRA FRANK
IPC: F16B31/00
Filed: 2001-03-01
Abstract: A method and apparatus for making a nut having a first end, a second end, and defining an orifice extending between the first end and the second end. A plurality of first threads are positioned in the orifice defined by the nut body, and a malformed thread is positioned in the orifice defined by the nut body, wherein the malformed thread interrupts continuity of at least one of the plurality of first threads.
Patent NZ-511096-A (NZ)
Title: Continuous positive airway pressure device
Inventor: SHAW GEOFFREY MARK
IPC: F15B1/00
Filed: 2001-04-12
Abstract: An air reservoir apparatus for a continuous positive airway pressure device, the air reservoir apparatus comprising: a rigid housing protecting an air reservoir having at least one air inlet/outlet; a plate arranged to apply a uniform pressure on the air reservoir, irrespective of the degree of inflation of the air reservoir, said plate being connected to the housing by substantially non distorting expandable framing, which can expand or contract to permit only rectilinear movement of the plate, in a direction substantially perpendicular to the plane of the plate, as the air reservoir respectively inflates or deflates.
Patent NZ-511334-A (NZ)
Title: Benzimidazolone derivatives useful as ion channel modulating agents
Inventor: STROBAEK DORTE
IPC: A61P25/28
Filed: 1999-12-03
Abstract: A benzimidazolone derivative or a pharmaceutically acceptable salt, oxide or hydrate thereof has the formula (I) wherein: X is N; R1 and R2 are independently H, alkyl or cycloalkyl; R3 and R4 are independently halogen, -NO2, -CN or CF3 and R5 is H. The compounds are useful for treating a disease or disorder responsive to modulation of SKca, IKca and/or BKca channels.
Patent NZ-511904-A (NZ)
Title: A pack
Inventor: COE ROBERT WILLIAM
IPC: B65D5/32
Filed: 2001-05-22
Abstract: A stack indexable lidded container formed from (i) a main blank sheet of material which defines at least the following (a) a generally square or rectangular base (save possibly for corner truncations thereof), (b) at least a pair of opposite walls (hereafter "side walls") and (c) a lidding flap from each such side wall, (ii) a blank of sheet material to provide a first wall (hereafter "end wall") other than a said side wall, and (iii) a blank of sheet material to provide a second wall (i.e. "second end wall") other than a said side wall; wherein said main blank and each end wall blank in the erected container together, as a result of their being coupled together at and/or adjacent the corner of said generally square or rectangular base (save possibly for corner truncations) thereof, define a corner column ("column" being as hereinbefore defined) structure at and/or adjacent each such corner; and wherein said end walls each defines an indexing upstand (hereafter "indexing projection") centrally thereof such that the pair of such upstands (one on each end wall) is receivable by a like container stacked thereon for indexing purposes, and wherein each end wall includes an inturned upper flange each having an opening therein on either side of the proximate indexing projection, each opening being adapted to receive a locking tab of the proximate lidding flap, the construction and arrangement being such that in an erected container, when the lidding flaps are closed, each end of each lidding flap is locked by a tab that has passed down into such an opening of an inturned flange, and such that each such tab can be uplifted from such an engagement to allow the opening of the container.
Patent NZ-512612-A (NZ)
Title: A method and means of producing a feed product containing a mixture of krill hydrolysate and a dry carrier (plant protein, dry krill, fish meal or byproduct meal)
Inventor: SAXBY DAVID J
IPC: A23J1/04
Filed: 1998-02-09
Abstract: Described is a method for removal of protein from non-stabilised and acid stabilised crustacean shell wastes.  The method comprises grinding non-stabilised crustacean shell wastes and water to a relatively small particulate size or grinding acid stabilised crustacean shell wastes to a described small particulate size, transferring said small particulate size product and desired shell wastes to a digester and adding a predetermined quantity of krill enzymes to the digester.  The mixture is then subjected to digestion for a predetermined time period at a predetermined temperature, the digested product is dewatered to obtain a first portion being relatively enzymatically active and relatively high in protein and a second portion of shell material or shell ash relatively high in chitin and low in protein. Also described is a method of producing a concentrated krill hydrolysate comprising the steps of harvesting krill having proteins and other nutrients and digesting the krill through enzymatic activity and partial hydrolysis to obtain liquid krill hydrolysate without deactivating enzymes in the krill, evaporating the krill hydrolysis to increase the percentage of solid in the krill hydrolysate relative to the liquid and to obtain the concentrated liquid krill hydrolsyate.  The harvesting, digesting and evaporation providing a partial hydrolysis and more nearly maintaining the initial structural characteristics of the proteins and other nutrients of the krill hydrolysate.
Patent NZ-512841-A (NZ)
Title: Method of obtaining calcium ions from lime by treating the lime with a polyhydroxy compound
Inventor: DE PAUW GERLINGS JOHANNES HEND
IPC: C01F11/02
Filed: 1999-12-07
Abstract: A method of obtaining a solution of calcium ions from lime, comprising: (i) Treating the lime with an aqueous solution of a polyhydroxy compound of the formula HOCH2(CHOH)nCH2OH (where n is 1 to 6); and (ii) Optionally separating insoluble impurities from the solution resulting from (i). Also described is a method of producing a precipitated calcium carbonate from carbide lime, comprising: (i) Treating the carbide lime with an aqueous solution of sorbitol to extract calcium from the carbide lime; (ii) Separating the insoluble impurities from the solution resulting from (i); and (iii) Treating the solution resulting from (ii) with carbon dioxide.
Patent NZ-516022-A (NZ)
Title: Combination of Lactobacillus and their use for the prevention and/or treatment of infections and inflammatory conditions
Inventor: DE SIMONE CLAUDIO
IPC: A23L29/00
Filed: 2000-06-16
Abstract: A combination of lactic acid bacteria comprises: (a) a first component consisting of at least one strain of H2O2-producing lactic acid bacteria, selected from the strains of the species Lactobacillus crispatus, Lactobacillus salivarius and Lactobacillus casei (b) a second component consisting of at least one strain of arginine-utilizing lactic acid bacteria, selected from the group consisting of the strains of the species Lactobacillus brevis, Lactobacillus gasseri and Lactobacillus fermentum. Provided that when component (a) is Lactobacillus casei, component (b) is not Lactobacillus gasseri or Lactobacillus fermentum and when component (a) is Lactobacillus crispatus, component (b) is not Lactobacillus fermentum. The combination may be in the form of tablets, sweets, chewing gum, gelatin capsules, pessaries, suppositories, micro-enemas, pellets, dental creams or gels, denture powders, moth washes, dentifrices, sprays, suspensions or ointments. The combination can be used in the manufacture of a food supplement, a hygiene product or a pharmaceutical composition for the treatment or prevention of infections and inflammatory conditions caused by bacteria, viruses or fungi, such as gingivitis, periodontitis, mucositis and stomatitis caused by drugs and/or physical agents, Behcet's syndrome, diakeratosis of the oral cavity, glossitis, sore throat, sialadenitis, sialolithiasis, pemphigus, Lichen planus, Sjögren's syndrome, vaginosis, vaginitis, urethritis, prostatitis, proctitis, otitis, conjunctivitis, rhinitis, sinusitis, leucoplakia, aphthae, herpes, and infections with Helicobacter pilori in the oral cavity.
Patent NZ-517922-A (NZ)
Title: Antibiotic preparation with a retarding active ingredient release
Inventor: VOGT SEBASTIAN
IPC: A61L31/16
Filed: 2002-03-21
Abstract: An antibiotic mixture composed of at least one amphiphillic component of a representative of the alkyl sulfates, aryl sulfates, alkylaryl sulfates, cycloalkyl sulfates, alkylcycloalkyl sulfates, alkyl sulfamates, cycloalkyl sulfamates, alkylcycloalkyl sulfamates, aryl sulfamates, alkylaryl sulfamates, alkyl sulfamates, fatty acid-2-sulfonates, aryl sulfonates, alkylaryl sulfonates, cycloalkyl sulfonates sulfonates, alkylcycloalkyl sulfonates, alkyl disulfates, cycloalkyl disulfates, alkyl disulfonates, cycloalkyl disulfonates, aryl disulfonates, alkylaryl disulfonates, aryl trisulfonates and alkylaryl trisulfonates as well as at least one antibiotic component from the from of aminogylcoside antibiotics, lincosamide antibiotics, 4-quinolone antibiotics and tetracycline antibiotics.
Patent NZ-519522-A (NZ)
Title: New indenoindolone compounds, a process for their preparation and pharmaceutical compositions containing them
Inventor: WIERZBICKI MICHEL
IPC: C07D209/80
Filed: 2002-06-12
Abstract: Indenoindolone compounds of formula (I) are described, wherein: R is H, optionally substituted alkyl, alkoxycarbonyl, NR10R11 or alkenyl, R1 to R8 is H, optionally substituted alkyl, hydroxy, acyloxy, NR12R13, carboxy, optionally substituted alkoxy, alkenyloxy, or two of R1 to R8 together form alkylenedioxy, X is oxygen or NR16, and R9 is H, aryl, heteroaryl or optionally substituted alkyl. The compounds are used in the manufacture of medicaments for use as anti-cancer agents.
Patent NZ-521866-A (NZ)
Title: Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof
Inventor: HOGENKAMP DERK J
IPC: C07D251/24
Filed: 2001-03-12
Abstract: Aryl substituted pyridines, pyrimides, pyrazines and triazines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein A1, A2, A3, R1-R4, X and Y are set in the specification. Also disclosed is the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhytmics and for the treatment of prevention of diabetic neuropathy.
Patent NZ-522153-A (NZ)
Title: Method and apparatus for fuel injection systems with choked flow and a tapered valve.
Inventor: HARRISON JOHN BLAKEMORE
IPC: F02M21/02
Filed: 2002-10-21
Abstract: An apparatus for a gaseous fuel injection system including: (i) A first chamber (2a) including an inlet (1) connectable with a source of gaseous fuel at a required inlet pressure; (ii) A second chamber (2b) connectable with an engine or other apparatus so as to supply gaseous fuel thereto and further connected with said first chamber through a controllable valving means (9); (iii) A flow control means (25) having an inlet connectable with an orifice means (25b) for controlling the pressure at the outlet of said flow control means (25) to be no more than 53% of the inlet pressure; (iv) Detection means for detecting said outlet pressure and controlling said valving means (9); (v) The arrangement being such that controlling the said flow control means (25) to adjust the flow of gaseous fuel therethrough controls the said outlet pressure which in turn controls said controllable valving means (9) and the pressure in said second chamber (2b), so as to thereby control the flow of gaseous fuel to said engine or other apparatus.