baber/WOPTO huggingface dataset:
Patent NZ-606427-A (NZ)
Title: Extended recombinant polypeptides and compositions comprising same
Inventor: CLELAND JEFFREY L
IPC: C07K17/00
Filed: 2010-02-03
Abstract: Disclosed is an isolated nucleic acid comprising a polynucleotide sequence which encodes a fusion protein comprising a biologically active protein and a first extended recombinant polypeptide (XTEN) wherein the XTEN comprises at least 36 amino acid residues and wherein the XTEN is characterized in that: (a) at least about 90% of the XTEN sequence consists of non-overlapping sequence motifs, wherein the sequence motifs are selected from the group consisting of SEQ IND NOS:182-203 and 1715-1722; (b) the sum of glycine (G), alanine (A), serine (S), threonine (T), glutamate (E) and proline (P) residues constitutes more than about 90% of the total amino acid sequence of the XTEN; (c) the XTEN sequence is substantially non-repetitive such that (i) the XTEN sequence contains no three contiguous amino acids that are identical unless the amino acids are serine residues, or (ii) within each of the sequence motifs, any two contiguous amino acid residues does not occur more than twice in each of the sequence motifs; (d) the XTEN sequence lacks a predicted T-cell epitope when analyzed by TEPITOPE algorithm, wherein the TEPITOPE algorithm prediction for epitopes within the XTEN sequence is based on a score of –9 or greater; (e) the XTEN sequence has greater than 90% random coil formation as determined by GOR algorithm; and (f) the XTEN sequence has less than 2% alpha helices and 2% beta-sheets as determined by Chou-Fasman algorithm.
Patent NZ-608210-A (NZ)
Title: Phospholipid depot
Inventor: CHEN HAILIANG
IPC: C07H15/234
Filed: 2010-12-17
Abstract: The disclosure relates to a method of making a clear depot (Figure 1). This depot comprises of a phospholipid, an oil, water, at least one hydrophilic water-soluble pharmaceutically active agent selected from vancomycin, gentamicin, a pharmaceutically acceptable salt thereof or a mixture thereof and a viscosity modifying agent selected from ethanol, isopropanol or a mixture thereof. The depot optionally contains a pH adjusting agent. The water present in the depot is no more than about 4wt % relative to the total weight of the depot and the depot has a pH of between about 4 and about 6. A method of administering the depot is also disclosed.
Patent NZ-612750-A (NZ)
Title: Improvements in prefabricated modular building units
Inventor: BRUCE THOMAS MCLEOD
IPC: E04G25/00
Filed: 2011-03-03
Abstract: Apparatus for supporting a ceiling support beam over a floor support beam (20) of a prefabricated modular building unit is disclosed. The apparatus includes an upper support (93) configured to be coupled to the ceiling support beam and a lower support (91) configured to be coupled to the floor support beam. A column (8) extends between the upper support and the lower support which is height adjustable. A tension rod (86) that connects to the lower support holds the column in compression between the upper support and the lower support in use. After construction the column is removed from the pre-fabricated modular building unit by releasing the tension and removing the rod.
Patent NZ-622112-A (NZ)
Title: Scheme for administering n-hydroxy-4-{ 2-[3-(n,n-dimethylaminomethyl)­benzofuran-2-ylcarbonylamino]ethoxy} benzamide
Inventor: KLOOS IOANA
IPC: A61P35/00
Filed: 2012-09-07
Abstract: Disclosed herein is the use of the compound of formula I N-hydroxy-4-{ 2-[3-{ N,N-dimethylaminomethyl)benzofuran-2-ylcarbonyl­amino]ethoxy} benzamide (abexinostat/PCI-24781): or an addition salt thereof with a pharmaceutically acceptable acid or base in the manufacture of a medicament for use in the treatment of cancer wherein the medicament is to be administered for 4 consecutive days, that period being followed by 3 consecutive days without any administration of compound of formula (I), in a human patient in need thereof. Also disclosed is the use in combination with a surgical, chemotherapy or hormone therapy treatment or with radiotherapy, wherein the chemotherapy treatment is not FOLFOX.
Patent NZ-630182-A (NZ)
Title: Method for measurement of peptidic degradation products of a proteolytic cascade in blood samples
Inventor: LOIBNER HANS
IPC: G01N33/68
Filed: 2012-06-06
Abstract: Disclosed is a method for measurement of peptidic degradation products of a proteolytic cascade comprising at least two consecutive proteolytic reactions in a biological sample, wherein the sample is incubated until the actual overall degradation rate of at least one peptidic degradation product is equal to the actual overall formation rate of said at least one peptidic degradation product and a steady state equilibrium is reached for said at least one peptidic degradation product involved in said proteolytic cascade and wherein said at least one peptidic degradation product in a steady state equilibrium concentration is quantified in the sample.
Patent NZ-631130-A (NZ)
Title: Texture analysis of a painted surface using specular angle data
Inventor: NORRIS ALISON M
IPC: G01N21/84
Filed: 2013-10-09
Abstract: A computer implemented method. The method includes obtaining (10), using a processor, spectral reflectance data from a spectrophotometric measurement of a target coating on a surface, wherein the measurement was taken at a specular angle, and removing (12), using the processor, at least a portion of the specular reflectance data that is attributable to a glossy coating of the surface. The method also includes constructing (14), using the processor, at least one spectral reflectance curve, and identifying (20), using the processor, at least one type of pigmentation effect of the target coating based at least in part on the at least one spectral reflectance curve.
Patent NZ-710882-A (NZ)
Title: Novel insulin analog and use thereof
Inventor: JANG MYUNG HYUN
IPC: C07K14/62
Filed: 2014-02-26
Abstract: The present invention relates to: an insulin analog, wherein the insulin titer is reduced compared with a natural form and the binding force to an insulin receptor is reduced in order to increase the half-life of insulin in the blood; a conjugate, wherein the insulin analog and a carrier are connected; an extended release preparation containing the conjugate; and a method for preparing the conjugate.
Patent NZ-722808-A (NZ)
Title: Method for locating animals
Inventor: AUER WOLFGANGG
IPC: A01K29/00
Filed: 2015-02-12
Abstract: The invention relates to a method for automatically locating an animal by means of radio waves and a plurality of nodes (1, 2, 3), wherein the animal is located on a ground (5) and is equipped with a node (1) of the radio locating system to be located and with one or more acceleration sensors. By evaluating the measurement results of the acceleration sensors, a conclusion is drawn about which activity the animal is presently performing and at which height above the ground (5) the node (1) is located. The calculation of the position of the node (1) to be located from the measurement results of the radio locating system is influenced by the assumption of said height as a constraint.
Patent NZ-726108-A (NZ)
Title: Substituted dihydroisoquinolinone compounds
Inventor: SUTTON SCOTT CHANNING
IPC: A61K31/47
Filed: 2015-06-05
Abstract: This invention relates to compounds of general formula (I) in which R1, R2, R3, R4, L, X and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
Patent NZ-730563-A (NZ)
Title: Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same
Inventor: THANOS CHRISTOPHER
IPC: C12N9/78
Filed: 2015-10-14
Abstract: Provided herein are variant adenosine deaminase 2 (ADA2) proteins. Also provided are ADA2 conjugates and compositions containing an ADA2 protein or conjugate. Also provided are methods and uses of the ADA2 proteins or conjugates for treating diseases and conditions, such as a tumor or cancer, and in particular any disease or condition associated with elevated adenosine or other associated marker.
Patent NZ-733186-A (NZ)
Title: Mixture of carboxylic acids for treating patients with kidney failure
Inventor: HERNÁNDEZ MIRAMONTES JORGE ANTONIO
IPC: A61K33/00
Filed: 2015-11-04
Abstract: Currently the treatment for patients with terminal kidney disease (stage V) consists in renal replacement therapy (hemodialysis, peritoneal dialysis or kidney transplant) which is extraordinarily expensive and engenders poor quality of life. The present invention is a mixture of carboxylic acids: citric acid, succinic acid, fumaric acid and malic acid, and any of the possible combinations thereof. Said product is preferably administered orally or intravenously, in the treatment of patients with chronic kidney disease, hyperammonemia or human conditions involving a negative nitrogen balance. This product is useful for reducing the serum values of urea and serum ammonium, while at the same time, by transamination of the oxaloacetate formed via succinate, fumarate and malate, it promotes the biosynthesis of non-essential, amino acids, and by transamination of the alpha-ketoglutarate formed via citrate, it generates glutamic acid and the amino acids related to same such as glutamine. This treatment prevents, preserves and even improves kidney function. In other patients it delays the deterioration of the kidney failure and the urgent need for renal replacement therapy. In others, it is used as a treatment that complements the renal replacement therapy in order to improve the quality of life of the patient and to improve the laboratory parameters.
Patent NZ-743361-A (NZ)
Title: An electron guiding and receiving element
Inventor: HU QIU-HONG
IPC: H01J35/08
Filed: 2015-12-04
Abstract: The invention relates to an electron antenna as an anode for a micro- or nano-focus X-ray generation comprising an antenna base (0345) and an antenna element (0335) arranged on the antenna base such that the antenna element protrudes from a front surface of the antenna base, wherein the antenna is arranged to guide and attract the electrons (0325) in its vicinity to the top the antenna element.
Patent NZ-748385-A (NZ)
Title: Crystal forms of crisaborole in free form and preparation method and use thereof
Inventor: CHEN MINHUA
IPC: A61P17/06
Filed: 2017-05-09
Abstract: The present invention relates to four crystal forms of crisaborole in free form and the preparation method thereof. The present invention also relates to the pharmaceutical composition containing the crystal forms and the use thereof.
Patent NZ-751062-A (NZ)
Title: Novel insulin analog and use thereof
Inventor: JANG MYUNG HYUN
IPC: C07K14/62
Filed: 2014-02-26
Abstract: The present invention relates to an insulin analog conjugate, the insulin analogue having a reduced insulin titer and a reduced insulin receptor binding affinity compared to the native form for the purpose of increasing the blood half-life of insulin, the conjugate prepared by linking the insulin analog and a carrier, a long-acting formulation including the conjugate, and a method for preparing the conjugate.
Patent NZ-758748-A (NZ)
Title: Lubricant composition for gear oil
Inventor: HYEUNG JIN LEE
IPC: C10M119/02
Filed: 2019-10-31
Abstract: The present invention relates to a lubricant composition, and more particularly to a lubricant composition, which includes an ethylene-alphaolefin oligomer and an alkylated phosphonium compound, thus realizing energy reduction and an increased endurance life, and which is thus suitable for use in gear oil. The lubricant composition of the present invention includes a base oil, a liquid olefin copolymer, and an alkylated phosphonium compound.
Patent NZ-770092-A (NZ)
Title: Methods and systems for virtual file storage and encryption
Inventor: EIKENBERRY JOHN
IPC: G06F21/62
Filed: 2016-02-10
Abstract: The present invention discloses an intelligent cloud server for cloud storage information management and encryption. In some embodiments, the intelligent cloud server can save and store documents without the need of first saving them in a local drive for upload. Upon storage, the document can be scanned and classified in a security level according to pre-determined settings and parameters. In some embodiments, depending on the classification, the system can encrypt portions of the document in order to facilitate the sharing and access of information in a secure way. Encryption keys and access to the encrypted portions are only provided upon authentication of the user, network, and/or need,according to corresponding protocols for the information.
Patent PT-102710-A (PT)
Title: Hydroelectric generator has water turbine that drives a dynamo which enables electrolysis of water to produce hydrogen for a fuel cell
Inventor: FERREIRA HENRIQUE MIGUEL MARQU
IPC: F01K25/00
Filed: 2001-12-28
Abstract: The generator has two water containers attached to the top and bottom of a common chain drive. The containers (J) move up and down alternately in sealed pipes (L) as they are filled with water at the top of the column and emptied at the bottom. The downward movement of the chain drives a dynamo (H) that provides electricity to an electrolyzing device (P) that produces hydrogen for a fuel cell (A)
Patent PT-115064-A (PT)
Title: Formulação para um sistema adesivo dentário universal contendo um monómero de reticulação dendrítico de segunda geração.
Inventor: JOANA VASCONCELOS E CRUZ
IPC: A61K6/00
Filed: 2018-10-08
Abstract: A PRESENTE INVENÇÃO ENQUADRA-SE NA ÁREA DOS SISTEMAS ADESIVOS DENTÁRIOS, E REFERE-SE MAIS ESPECIFICAMENTE A UMA FORMULAÇÃO PARA UM SISTEMA ADESIVO DENTÁRIO UNIVERSAL. É OBJECTO DA PRESENTE INVENÇÃO UMA FORMULAÇÃO PARA UM SISTEMA ADESIVO DENTÁRIO QUE COMPREENDE UM MONÓMERO DE RETICULAÇÃO DENDRÍTICO DE SEGUNDA GERAÇÃO COM PELO MENOS OITO EXTREMIDADES. ADICIONALMENTE, É TAMBÉM OBJECTO DA PRESENTE INVENÇÃO UM PROCESSO DE OBTENÇÃO DA FORMULAÇÃO QUE COMPREENDE O REFERIDO MONÓMERO DE RETICULAÇÃO DENTRÍTICO DE SEGUNDA GERAÇÃO.
Patent PT-115083-A (PT)
Title: Nano-corantes, métodos de obtenção e usos dos mesmos
Inventor: MARIA MANUELA ESTEVEZ PINTADO
IPC: C08L5/08
Filed: 2018-10-17
Abstract: A PRESENTE DIVULGAÇÃO REFERE-SE A NANO-CORANTES, SUA PRODUÇÃO E USOS DOS MESMOS; EM PARTICULAR NA INDÚSTRIA TÊXTIL, NOMEADAMENTE ARTIGOS TÊXTEIS TINGIDOS. A PRESENTE DIVULGAÇÃO REFERE-SE A NANO-CÁPSULAS ANTIMICROBIANAS PARA TINGIR TÊXTEIS DE FIBRAS OU TECIDO, COMPOSTO DE QUITOSANO COMO MATERIAL ENCAPSULANTE E PELO MENOS, E 0.1 MG/ML DE UM CORANTE, EM QUE O CORANTE É ENCAPSULADO PELO MATERIAL DE ENCAPSULAMENTO. A NANO-CÁPSULA DA PRESENTE DIVULGAÇÃO MELHORA O EFEITO ANTIMICROBIANO DO ARTIGO TINGIDO E MANTÉM O ARTIGO TINGIDO COM SOLIDEZ DE COR.
Patent RU-94010148-A (RU)
Inventor: STEPANOV S I
IPC: F25J1/00
Filed: 1994-03-22
Abstract: FIELD: industries where effective cooling agent is requires, such as in mining industry for rescue operations at high ambient temperatures. SUBSTANCE: generator has tank and cylinder filled with liquid carbon dioxide both interconnected by means of piping through hydraulic lock and also has perforated pipe placed inside tank perpendicular to hydraulic lock axis; hydraulic lock is installed in tank wall for displacement under excess pressure action; perforated pipe is passed through tank walls in a spaced relation. Liquid carbon dioxide is fed from cylinder to tank through hydraulic lock adjusted to triple-point pressure of carbon dioxide. At tank pressure lower than triple-point pressure of carbon dioxide, the latter is sublimated and thickening solid phase is formed. When pressure of gases discharged through perforated pipe rises above permissible value, hydraulic lock is pushed out to external medium. EFFECT: improved design, enlarged functional capabilities.
Patent RU-94020973-A (RU)
Inventor: ERMILOV N G
IPC: H02K57/00
Filed: 1994-06-06
Abstract: FIELD: starting internal-combustion engines and trickle charging storage batteries. SUBSTANCE: engine flywheel toothed rim has its diameter several times larger than that of shaft-mounted gear. During starting period, shaft-mounted gear functions as driving gear and toothed rim, as driven wheel whose speed is low but sufficient for starting the engine. Under these conditions, starter-generator runs as motor. Upon starting, toothed rim starts rotating at much higher speed and runs as driving wheel while shaft-mounted gear becomes driven gear and rotates at much lower speed. EFFECT: provision for reversibility of machine due to its change in functions with time. 5 dwg
Patent RU-94022465-A (RU)
Inventor: BEDEL DID E
IPC: C07C247/02
Filed: 1994-06-09
Abstract: FIELD: organic chemistry; production of building materials. SUBSTANCE: proposed foamable composition comprises polymer-based mixture and bloating agent taken in effective amount sufficient to cause foaming of polymer. Bloating agent comprises at least one α,β-hydroxylated hydrocarbon belonging to class of azides. EFFECT: invention can be used for production of synthetic foam plastics and products made from them.
Patent RU-94024812-A (RU)
Inventor: NOVITSKIJ I A
IPC: A61K39/00
Filed: 1994-06-29
Abstract: FIELD: medicine. SUBSTANCE: method involves the administration of living poliomyelitis vaccine. Settled population were vaccinated at the age 3; 4.5; 6 months; 3; 8; 17 years and above 17 years - according the results of serological inspection. Migratory population were vaccinated at the age from 3 months to 6 years three times at interval between vaccinations at least 1.5 month (not less); at the age 7 years - once (at positive serological inspection) or at the age 7, 13 and 17 years (at absence of serological inspection). EFFECT: enhanced effectiveness of prophylaxis.
Patent RU-94025129-A (RU)
Inventor: KAGANOV V S
IPC: B23B21/00
Filed: 1994-07-05
Abstract: FIELD: machine tools. SUBSTANCE: bosses with cylindrical boring are made in point of unit casing subjected to the highest amplitude of vibration. The boring are filled with ring members that make an interference fit in internal diameter of the boring. The members are made of elastic material of high damping, put on bolts passing through all ring members. The damps are inserted in points where the highest damping effect may be created. Damping level may be adjustable at the expense of material, size and interference selection. EFFECT: vibration resistance. 1 dwg
Patent RU-94030614-A (RU)
Inventor: BUROCHKIN JU P
IPC: B23C5/06
Filed: 1994-08-18
Abstract: FIELD: mechanical engineering. SUBSTANCE: openings in supports are provided with pins made up as eccentrics. The presence of an eccentricity allows the plate to move in the axial direction after grinding. EFFECT: expanded functional capabilities.
Patent RU-94030620-A (RU)
Inventor: POLSTJANOV A E
IPC: A23L27/10
Filed: 1994-08-18
Abstract: FIELD: food industry. SUBSTANCE: raw for taste-aromatic addition preparing: fresh apple or apple juice, fresh cranberry, fresh sea-buckthorn fruits, rose fruits, dill, coriander, peppermint leaves, sage, major plantain leaves, matricary flowers, haw-thorn flowers and fruits, milfoil herb. Rectified ethanol at concentration 25 vol.% is used for extraction of bioactive substances and essential oils from fruits, berries and herb and an aqueous-spirituous extracts were used for taste-aromatic addition preparing therefore. Bioactive addition has: honey, sugar, color, haw-thorn aqueous-spirituous extract; fruit-berry component: cranberry, apple, sea-buckthorn liqueur or their mixture; extract of spice-aromatic plants: peppermint aqueous-spirituous extract at the following ratio of components, wt.-%: honey 1-7; sugar 3-10; haw-thorn aqueous-spirituous extract 0.5-1.1; peppermint aqueous-spirituous extract 0.7-1.8; cranberry, apple or sea-buckthorn liqueur or their mixture - the rest. Ratio of cranberry and apple liqueur in mixture is 1: 2.5 and that of cranberry and sea-buckthorn liqueur is 1:6. Depending on fruit-berry component addition can additionally contain rose, matricary, milfoil, plantain aqueous-spirituous extracts and coriander, sage and dill aqueous-spirituous extracts as spice-aromatic components. EFFECT: immunostimulating, disinfecting, vitaminizing actions, enhanced quality, curative-prophylaxis action.
Patent RU-94041979-A (RU)
Inventor: OSIPENKO A V
IPC: G01N33/49
Filed: 1994-11-25
Abstract: FIELD: medicine. SUBSTANCE: method involves studying energetic properties of blood mononuclears at the seventh-tenth day after operation, that is, mononuclear endogenous respiration speed and respiration speed in presence of exogenous succinic acid using polarography method. The mononuclear endogenous respiration speed at the end of postoperative period being less than 80%, significant shift in respiration speed in presence of exogenous succinic acid being greater than 130%, disturbed bone tissue regeneration process in distraction osteosynthesis is to be diagnosed. The mononuclear endogenous respiration speed at the end of postoperative period being greater than 150%, activation of respiration speed in presence of exogenous succinic acid achieving 120%, favorable bone tissue reparation process development is judged to take place. EFFECT: enhanced accuracy and simplified method.
Patent RU-94046250-A (RU)
Inventor: MANFRED LJUKING
IPC: B66C13/06
Filed: 1993-06-01
Abstract: FIELD: materials handling. SUBSTANCE: load lifting device has horizontally moving unit, for instance, load truck 1. Load pressing device, for instance, spreader 4 is suspended through six or more hydraulic cylinders 11-16 individually adjustable in length. Each cylinder is installed through spatially displaced hinge joints 21-26 and 31,32 on unit 1 and on load taking device 4. At least four operating cylinders 11-16 are installed with tilting. Hinge joints 21-26 or 31,32 of operating cylinders are preferably arranged over imaginary circumference both on movable unit 1 and on load taking device 4. With load acting vertically only, it is preferable to use eight operating cylinders four of which are to be arranged vertically and, if viewed from top, are placed at corners of imaginary rectangle or square. Every two operating cylinders are installed in four imaginary planes so that one is tilted. Tilting of cylinders is directed in opposition to each of two imaginary parallel planes. EFFECT: prevention of swinging, increased reloading capacity. 1 dwg
Patent RU-95100219-A (RU)
Inventor: BELOUSOV A V
IPC: E21B1/30
Filed: 1995-01-10
Abstract: FIELD: well drilling. SUBSTANCE: exhaust pipe is made in the form of cylinder 20 with radial slots 22 and 23 and blind bottom 21, secured in central channel 18 of drill bit 17 on the side of open face. Accumulating chamber 24 open to travel chamber 13 is formed beyond blind bottom 21 of cylinder 20 in the central channel of striking piston 12. EFFECT: enhanced operate reliability and striking capacity at the expense of simplified exhaust path, enhanced strength of the exhaust pipe made in the form of blind bottom cylinder and radial slots, simplified design of striking piston, as well as due to increased accumulating volume of travel chamber. 2 cl, 1 dwg
Patent RU-95107402-A (RU)
Inventor: PLAVIL SHCHIKOV A A
IPC: G01R23/16
Filed: 1995-05-06
Abstract: FIELD: measurement technology. SUBSTANCE: When digitizing and quantizing a signal under study, K sequences of digitized values of the signal are generated. Each sequence has its own sampling rate. The digitized values are passed through digital bandpass filters and digital low-pass filters. Signals from the bandpass filter outputs are treated to determine information parameters of the bandpass signals. EFFECT: extended functional capabilities of the method due to localization of discrete components of spectra and measurement of their parameters; higher accuracy in measuring parameters of signal spectrum continuous component.