baber/WOPTO huggingface dataset:
Patent PH-24681-A (PH)
Title: 7-((3-(aminomethyl)-3-alkyl)-1-pyrrolidinyl)-quinoline-carboxylic acids
Inventor: DOMAGALA JOHN MICHAEL
IPC: A61P31/04
Filed: 1987-07-27
Abstract: Novel, orally active antibacterial agents of formula I <CHEM> are described characterized as 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-ox o-3-quinol ine carboxylic acids or corresponding 1,8-naphthyridine derivatives as well as methods for their manufacture and pharmaceutical compositions containing them.
Patent PH-26542-A (PH)
Title: Use of X-phenyl-1,2,3,4-tetrahydro-1-naphthaleneamine derivatives in the treatment of psychosis inflammation and as immunosuppressants
Inventor: KOE BILLIE KENNETH
IPC: A61K31/13
Filed: 1990-03-07
Abstract: 4-Phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives have been found useful for the treatment of pyschosis, inflammation, stroke and as imnunosunpressants.
Patent PH-30758-A (PH)
Title: Hair styling compositions containing a silicone grafted polymer and low level of a volatile hydrocarbon solvent.
Inventor: SANSFEV MIDHA
IPC: A61K8/00
Filed: 1994-08-02
Abstract: Provided hair styling compositions comprising: (a) from about 0.1% to about 15%, by weight, of a silicone grafted adhesive polymer, said polymer being characterized by an organic polymeric backbone having silicone macromers grafted to said backbone; (b) from about 0.5% to about 15%, by weight, of a hydrocarbon solvent selected from the group consisting of C10-C14 branched chain hydrocarbons, and mixtures thereof; (c) a polar solvent phase comprising from about 80% to about 98.9%, by weight of the composition, of a polar solvent selected from the group consisting of water and C2-C3 monohydric alcohols, and mixtures thereof, wherein said composition contains no more than about 15%, by weight, of C3 monohydric alcohol; wherein said organic polymer backbone is soluble in said polar solvent phase, and said silicone macromers of said hair setting polymer are soluble in said hydrocarbon solvent and insoluble in said polar solvent. In preferred embodiments, the compositions hereof additionally comprise a plasticizer for the silicone grafted hair setting polymer. Especially preferred plasticizers include acetyl tri-C2-C8 alkyl citrates, particularly acetyl triethyl citrate.
Patent TR-26206-A (TR)
IPC: A61Q9/02
Filed: 1991-09-27
Abstract: A shaving unit that comprises at least one blade and a shaving composite has a surface for engaging the user's skin adjacent the blade edge. The shaving unit may be of a disposable cartridge type adapted for coupling to and uncoupling from a razor handle or may be integral with a handle so that the complete razor is discarded as a unit when the blade or blades become dulled. The blade edge (or edges) cooperate with skin engaging surfaces to define shaving geometry. The skin-engaging surface includes a shaving aid composite that is a mixture of water insoluble matrix material, an effective amount of shaving aid material, and an effective amount of water-insoluble essential oil material, the water-insoluble essential oil material being delivered from the shaving aid composite concurrently with the delivery of the water-leachable shaving aid material during shaving to apply at least about one nanogram of the essential oil to the skin surface per square centimeter of skin surface.
Patent UY-32779-A (UY)
Title: Cianobutiratos sustituidos con accion herbicida
Inventor: ELMAR KIBLER DR
IPC: A01N37/34
Filed: 2010-07-08
Abstract: Cianobutiratos sustituidos de la fórmula I en donde las variables se definen de acuerdo con la descripción. Procesos e intermediarios para preparar los compuestos de la fórmula I y sus N-óxidos, sus sales útiles en la agricultura, composiciones que los comprenden y sus uso como herbicidas, así como métodos para controlar la vegetación indeseada.
Patent UY-33410-A (UY)
Title: Uso de teriflunomida para mantener el nivel de fatiga de un paciente que tiene esclerosis multiple
Inventor: MAEVA GERME
IPC: A61K31/16
Filed: 2011-05-26
Abstract: La presente invención se refiere al uso de teriluonomida para mantener el nivel de fatiga de un paciente que tiene esclerosis múltiple (EM)
Patent UY-35393-A (UY)
Title: Nuevos compuestos inhibidores de la fosfodiesterasa del tipo 10a
Inventor: JANTOS KATJA
IPC: C07D495/04
Filed: 2014-03-12
Abstract: Compuestos de la fórmula I, los N-óxidos, tautómeros, las prodrogas y las sales farmacéuticamente a ceptables de los mismos:  En fórmula I la variable X1 es CH o N, X2 es O o S, y R1, R2, R3, R4 y Q  son según se los definió en las reivindicaciones.  Los compuestos de la fórmula I, los N-óxidos, tautómeros, las prodrogas y las sales farmacéuticame nte aceptables de los mismos son inhibidores de la  fosfodiesterasa del tipo 10A. Por lo tanto, la invención también se refiere al uso de los compues tos de la fórmula I, los N-óxidos, tautómeros, las prodrogas y las sales farmacéuticamente aceptabl es de los mismos para la fabricación de un medica mento y que por lo tanto son apropiados para tratar o controlar trastornos médicos que se seleccion an entre: trastornos neurológicos y trastornos ps iquiátricos, para mejorar los síntomas asociados con dichos trastornos y para reducir el riesgo de  dichos trastornos.
Patent UY-36404-A (UY)
Title: ANTICUERPOS MONOCLONALES (Ab) COMO DETECTORES DE CD73 E INHIBIDORES DE SU ACTIVIDAD ENZIMÁTICA, Y COMPOSICIONES QUE LOS CONTIENEN
Inventor: KORMAN ALAN J
IPC: C12P21/08
Filed: 2015-11-19
Abstract: Se divulgan anticuerpos monoclonales aislados que se fijan al Cúmulo de Diferenciación 73 (CD73) humano, inhiben la actividad de CD73 y median la internalización de CD73 dependiente de anticuerpo. Se proporcionan moléculas de ácido nucleico que codifican los anticuerpos de la invención, vectores de expresión,células huésped y métodos para expresar dichos anticuerpos. Se proporcionan inmunoconjugados, moléculas biespecíficas y composiciones farmacéuticas que comprenden los anticuerpos de la invención, asi como métodos para inhibir el crecimiento de una célula tumoral que expresa CD73 usando los anticuerpos de la invención, ymétodos para tratar distintos tipos de cáncer.
Patent UY-37326-A (UY)
Title: Dispersiones sólidas extruidas por fusión que contienen un agente inductor de apoptosis
Inventor: TONG PING
IPC: A61K31/496
Filed: 2017-07-13
Abstract: Una dispersión sólida pro-apoptótica que comprende, en una forma esencialmente no cristalina, un compuesto inhibidor de familia de proteínas Bcl 2 de la Fórmula I, definido en la presente, disperso en una matriz sólida que comprende (a) un vehículo polimérico soluble en agua farmacéuticamente aceptable y (b) un agente tensioactivo farmacéuticamente aceptable y proceso para preparar dicha dispersión sólida. La dispersión sólida es apropiada para administración por vía oral para tratar una enfermedad caracterizada por la sobreexpresión de una o más proteínas antiapoptóticas de la familia Bcl-2, por ejemplo cáncer o una enfermedad inmune o autoinmune.
Patent UY-38050-A (UY)
Title: Anticuerpos pac1 y sus usos referencia cruzada a solicitudes relacionadas
Inventor: IRWIN CHEN
IPC: C12P21/08
Filed: 2019-01-11
Abstract: La presente invención se refiere a anticuerpos neutralizantes del receptor de tipo I del polipéptido activador de la adenilato·ciclasa hipofisaria (PAC1) humano y composiciones farmacéuticas que comprenden tales anticuerpos. También se describen métodos para tratar o prevenir afecciones que producen cefaleas, tales como migraña y cefalea en brotes, utilizando los anticuerpos neutralizantes.
Patent UY-39075-A (UY)
Title: Moléculas de adn reguladoras de la expresión génica de plantas; construcciones, plantas y sus partes, y productos que las comprenden
Inventor: FOAT BARRET C
IPC: C12N15/29
Filed: 2012-05-11
Abstract: Se describen moléculas de ADN y constructos, incluyendo secuencias de nucleótidos, útiles para modular la expresión de genes en plantas y células de plantas, plantas, células y partes de plantas, semillas y productos que comprenden las moléculas de ADN unidas operablemente a polinucleótidos heterólogos transcribibles, así como los métodos de uso.
Patent YU-10798-A (YU)
Inventor: RADOICA MILOSEVIC
Filed: 1998-03-12
Abstract: Koaksijalni motor na principu četvorotaktnog oto- ili dizei-motora, sastoji se od cilindarskog bloka (1) sa cilindrima (2) u koaksijalnoj konfiguraciji, koji su sa gornje strane zatvoreni cilindarskom glavom (3) a sa donje strane kućištem motora (4). Pri tome su klipovi (5) preko osovinica (6) i klipnjača (7) zglobno povezani sa ekscentričnim vratilima (8), čiji su konusni zupčanici (11) uzubljeni u zajednički konusni zupčanik (12) na glavnom vratilu (13). Prenosni odnos konusnih zupčanika (2:1) omogućava direktan pogon razvodnika paljenja (25) ili pumpe visokog pritiska pomoću glavnog vratila. Preko usisnog i izduvnog kolektora, razvodnih kanala i razvodnih otvora (18) i (19), glavno vratilo vrši direktno napajanje motora radnom materijom i odvodjenje sagorelih gasova. Vratno šestcilindrično šestaktno rešenje koaksijalnog motora namenjeno je za termodinamičku transformaciju energije goriva u pneumatsku, a trocilindrično varijantno rešenje je u funkciji pneumatskog motora. Varijantna rešenja su namenjena za pneumatski pogon vozila.
Patent YU-17301-A (YU)
Inventor: EDVARDSSON DANIEL
IPC: C07K14/81
Filed: 1999-09-02
Abstract: Daje se EtO2C-CH2-(R)-Cgl-Aze-Pab-OH ili njegova farmaceutski prihvatljiva so, u obliku koji je u suštini kristalan. Nadjeno je da kristalni oblici EtO2C-CH2-(R)-Cgl-Aze-Pab-OH imaju visoku hemijsku stabilnost u čvrstom stanju, u poredjenju sa amorfnim oblicima istog jedinjenja.
Patent YU-40689-A (YU)
Title: Prevojno zaglavlje za ležaj na sklapanje
Inventor: MC NAMARA G
IPC: A47C17/52
Filed: 1989-02-24
Abstract: PREVOJNO ZAGLAVLJE ZA LEŽAJ NA SKLAPANJE. Automatsko prevojno zaglavlje za ležaj za zidno sklapanje, kada je ležaj u svom horizontalnom položaju spremnom za korišćenje, radi pokrivanja udubljenja u zidu ili ormanu u koje se ležaj sklapa. Zaglavlje automatski biva previjeno u sklopljeni položaj usled dovoljenja ležaja u vertikalni položaj kada je isti van upotrebe, a da nisu potrebne posebne mehaničke ili manualne kretnje korisnika. Sklop zaglavlja se selektivno oslobadja i tako obezbedjuje pristup do zglobnog mehanizma ležaja.
Patent YU-48996-A (YU)
Inventor: ISAK GRADJIN
Filed: 1996-09-02
Abstract: Novo konstruktivno rešenje u oblasti izolacionog materijala u gradjevinarstvu, a koje obezbedjuje efikasnu izolaciju, zdravu izolaciju, jednostavnu i brzu ugradnju, jednostavnu izradu i dr. Konstrukcija se sastoji u tome što se u telu (1) pričvršćuje ventil (4), postavlja staniol folija (2) i zatim hermetički zatvori poklopcem (3) pa potom izvuče vazduh iz cele ploče, a preko ventila (4).
Patent AT-A157995-A (AT)
Inventor: GASTBERG INGOLF DIPL ING
IPC: E21C35/22
Filed: 1995-09-22
Abstract: Disclosed is a device intended to reduce the danger of inflammability during the operation of a partial-cut tunnelling machine, the device having nozzles designed to eject air and/or an air/water mixtures. The device includes a cutter arm (3) on which the nozzles are mounted with their output axes (11) oriented so that the jets impact the heap of debris lying in front of the loading device (7).
Patent AT-A180191-A (AT)
IPC: A61K33/24
Filed: 1991-09-10
Abstract: Pharmaceutical prepn. comprises: (a) a salt of ranitidine (I) with a bismuth complex of tartaric or citric acid; and (b) an alkali salt. Pref., the salt is e.g. -N-(Q)-N'-methyl-2-nitro -1,1-ethenediamine-2-hydroxy -1,2,3-propanetricarboxylate -bismuth (3+).
Patent BE-893834-A (BE)
Title: House heating system using solar heat - conveys warm air from double layer roof to heat storage system in cellar
IPC: F24D11/00
Filed: 1982-07-14
Abstract: The method of warming a house using heat obtained from the sun, uses the space between the double layers of a sloping roof as a heat source. The warmed air is extracted by a suction system using a tube which carries the air to the cellar. The warmed air is then circulated through ducts between layers of ballast forming a heat storage unit, and enclosed by insulation. The warmed air obtained can then be discharged later in quantities regulated by control flaps through ducts terminating under grids in the floors of rooms above.
Patent BE-898176-A (BE)
Title: Procédé de fabrication d'un conduit à isolation thermique.
IPC: B29D23/00
Filed: 1983-11-08
Abstract: Pour obtenir un conduit à isolation thermique présentant une bonne flexibilité, formé d'un tube de métal, d'une couche isolante de matière synthétique expansée et d'une enveloppe externe, on forme l'enveloppe externe d'une bande souple, dont les bords, qui se chevauchent, sont collés l'un à l'autre. L'épaisseur de la bande est de 0,08 à 0,40 mm. Pendant la production de la couche d'isolation, l'enveloppe externe est soutenue de l'extérieur. On utilise comme matière expansée une mousse de polyuréthane flexible.
Patent BE-899210-A (BE)
Title: Housing for indicator lamps associated with vehicle headlamp - whose failure is signalled by switching of warning lamps
IPC: B60Q11/00
Filed: 1984-03-21
Abstract: Current supply to the 6V headlamp is taken via the coil of a 6V relay controlling the switching of red and green 12V warning lamps. While the headlamp is functioning correctly, the relay is energised and the green lamp is alight. If the headlamp is burnt out the relay is de-energised and the red lamp is alight instead. - The operation of the headlamp is not affected if either of the warning lamps should fail. A 12V standby headlamp is connected to the relay contact so as to become illuminated in conjunction with the red warning lamp on failure of the main headlamp. An additional (amber) warning lamp may be provided and operated by a subsidiary relay upon failure of the green lamp.(0/4)
Patent BE-905446-A (BE)
Title: Installation de rabotage a rabot a socle.
IPC: E21C27/34
Filed: 1986-09-17
Abstract: Le guide de chaine est formé par des capots (14) se raccordant aux éléments de gouttière du coté du remblai. Les capots sont reliés aux barres de glissière (16) par des assemblages à tenon et mortaise (28), de telle façon que des mouvements longitudinaux entre les éléments de gouttière et les barres de glissière sont possibles, et qu'en outre le tronçon de gouttière du convoyeur peut se soulever au passage du socle. Des verrous (36) conformés en organe de blocage qui assurent l'emboitement des tenons des assemblages à tenon et mortaise, sont rattachés auxdits assemblages à tenon et mortaise.
Patent BE-764542-A (BE)
Title: Improved die and punch
IPC: C04B35/645
Filed: 1971-03-19
Abstract: Improved die and punch In the manufacture of SiN powder, compacts, the use of a floating mandrel made from SiN improves the thermal insulation properties of the equipment. reduction in main punch size may also be effected. The floating mandrel is positioned between the means of applying the pressure from the machine and the head of the punch. The mating surface of the tubular die, the bottom plug, the flat working surface and the floating mandrel may be coated with a further refractory powder.
Patent CA-1039402-A (CA)
Inventor: BOUWHUIS GIJSBERTUS
IPC: G11B7/013
Filed: 1974-07-02
Granted: 1978-09-26
Abstract: ABSTRACT:     A record carrier is described on which information is recorded in an optical structure of trackwise arranged areas and intermediate areas.          By adapting the average dimensions of the areas to the average spatial frequencies on the record carrier a read signal can be obtained of sufficient modulation depth and minimal distortion.
Patent CA-1040347-A (CA)
Inventor: UENO HARUO
IPC: C08F136/06
Filed: 1974-09-18
Granted: 1978-10-10
Abstract: PROCESS FOR PRODUCING BUTADIENE POLYMERS                 ABSTRACT OF THE DISCLOSURE         A butadiene polymer consisting essentially of syndiotactic 1,2-polybutadiene is produced by the successive steps of: (A) preparing a catalyst component solution by dissolving, in an inert organic solvent containing 1,3-butadiene, a cobalt compound, soluble in the organic solvent, such as (i) cobalt-.beta.-diketone complex, (ii) cobalt-.beta.-keto-acid ester complex, (iii) cobalt salt of organic carboxylic acid and (iv) halogenated cobalt-ligand compound complex, and on organoaluminum compound, (B) preparing a catalyst composition by mixing the catalyst component solution with an alcohol, ketone or aldehyde compound and carbon disulfide; (C) providing a polymerization mixture containing desired amounts of 1,3-butadiene, the catalyst composition and an insert organic solvent, and (D) polymerizing 1,3-butadiene at a temperature of -20°C to 80°C.
Patent CA-1041717-A (CA)
Inventor: KRUDER GEORGE A
IPC: B29C48/76
Filed: 1974-10-23
Granted: 1978-11-07
Abstract: Abstract A rotary screw extruder and a method are provided to both devolatilize and dry plasticized resinous hygroscopic materials during extrusion thereof into a finished product of indefinite length.  The extruder includes a screw having three successive pumping sections and a pair of vent sections.  Each vent section separates two of the successive pumping sections. The first pumping section meters plasticized material through-flow.  The intermediate pumping section has partially full channels that permit a continuous, helical passage to inter-connect the two vent sections.  The partially full channels establish a free surface which promotes devolatilization and drying.  The third pumping section pressurized the devolatilized and dried plasticized material for extrusion through a con-ventional die orifice.  The devolatilizing and drying method begins by controlling the flow rate of plasticized material into a gas removal zone.  The gas removal zone is provided with a flow capacity exceeding the controlled flow rate of plasticized material so that a helical, free surface exists throughout the gas removal zone.  Each end of the gas removal zone is connected to a reduced pressure source.  The plasticized material is worked as it goes through the gas removal zone to heat the material, to promote drying and devolatilization thereof, and to maintain a uniform flow rate.
Patent CA-1037398-A (CA)
Inventor: HARRISON DAVID E F
IPC: C12N1/30
Filed: 1974-11-21
Granted: 1978-08-29
Abstract: ABSTRACT      A process for the production of micro-organisms in which a methane-utilising micro-organism which is a strain of Methylomonas is grown under aerobic conditions in a liquid growth medium comprising assimilable sources of nitrogen and essential mineral salts, in the presence of methane gas and in the presence of (a) one or more methanol-utilising micro-organisms  which is/are capable of metabolising methanol produced by the growing methane-utilising micro-organism, and (b) one or more non-methylotrophic micro-organisms which is/are capable of metabolising organic substances produced by the methane and/or methanol-utilising micro-organisms.
Patent CA-1042683-A (CA)
Inventor: CONVERSE VERNON G III
IPC: G01M15/10
Filed: 1974-12-24
Granted: 1978-11-21
Abstract: A B S T R A C T           This application discloses a method and apparatus for hot testing on a production basis, automobile engines as they come off the assembly line, for the purpose of performing a final check on such engines before they are installed in the automobile.  While previously, automotive engines have been subject to many checks of their individual systems before reaching a condition where they are to be installed in an automobile, for example, by checking of the carburation system and the ignition timing, there has been no final check of the engine, to make sure the three main systems of the automobile engine (i.e., carburetion, ignition and combustion) are all working properly together before installing the engine in the automobile.         After much work it was found that such a test could be performed on the engine by running it under load and examining certain exhaust gas emissions.  It has been found that carbon monoxide (CO) and hydrocarbons (HC) are the most perceptive indicators of engine malfunctions.  Accordingly, the green engines coming off the assembly line are tested at three key points or KEY MODES of operation at which emission related engine malfunctions are most likely to appear, if they exist.  These points of operation are high cruise, low cruise, and idle.  The engine, after it comes off the assembly line is placed in a production test stand wherein the connections for water, oil and exhaust are made, the engine is started, accelerated to the high cruise speed, and allowed to warm up for a predetermined time, after which time, measurements of HC and CO are taken and an  appropriate indicator light lit to indicate that the engine either is within limits of HC and CO at this speed, or does not pass for some reason.  The same procedure is followed in the low cruise and idle speeds.  If the engine passes all three modes of operation, it is removed from the test stand and passed for installation in the motor vehicle.  If one or more of the indicator lights show a reject condition, the engine is automatically removed from the pro-duction test stand and routed to a repair loop for further testing.  The CO and HC evaluations at the production test stand may be recorded on a manual or automatic system to arrive coincident with the engine at the repair stand.  In the repair loop, adjustment or repair to correct malfunctions is facilitated by the use of a truth chart having a reject pattern matching that shown by the recording system.  Both in the production test stand and in the repair loop, a fixed-filled power absorption device automatically provides a pre-determined constant engine load at a predetermined r.p.m. for each point of operation, in accordance with the conventional cube power/speed curve.
Patent CA-1062532-A (CA)
Inventor: VAN ENGELAND JOZEF L
IPC: G03G5/10
Filed: 1975-05-06
Granted: 1979-09-18
Abstract: Abstract of the disclosure A process for obtaining a fixed toner image on a sheet or web material comprising the steps of image-wise depositing toner particles on a thermo-adhesive fixing layer that itself permanently adheres to a support and heating said material carrying the toner image in such a degree that softening of the thermo-adhesive fixing layer takes place without reaching a temperature at which permanent deformation of the support occurs, wherein the support is a thermoplastic resin support whose glass transition temperature (Tg) is higher than the glass transition temperature (Tg) of the thermoplastic polymer or polymer composition of the thermo-adhesive layer and the toner particles comprise at least 10 % by weight of a polymer or polymer composition whose glass transition temperature (Tg) is at least 10°C higher than that of the thermoplastic polymer or polymer composition of the thermo-adhesive fixing layer.
Patent CA-1054211-A (CA)
Inventor: FORGO GABOR
IPC: G03G15/09
Filed: 1975-05-16
Granted: 1979-05-08
Abstract: A PROCESS FOR ELECTROGRAPHIC IMAGE PRODUCTION AND AN APPARATUS FOR CARRYING OUT THIS PROCESS     ABSTRACT OF THE INVENTION    A process for a latent electrostatic image or a conductivity image on a photoconductor, a single component magnetic toner being used for development and a magnetic brush being used not only for application of the toner to the image, but also for removal of residual toner.  The brush may be one and the same brush for both tasks or separate brushes identical in structure may be used for each of the two tasks.
Patent CA-1071228-A (CA)
Inventor: TILLY GUY
IPC: C07C231/12
Filed: 1975-05-30
Granted: 1980-02-05
Abstract: ABSTRACT OF THE DISCLOSURE     This invention  relates to compounds of the formula;                          I   in which:   R1 represents a hydrogen atom or a radical of the formula   in which R4 and R5 represents, independently of each other, a hydrogen atom or a lower alkyl radical, R2 represents a hydrogen atom or a lower alkanoyl radical, R3 represents a hydrogen atom, a lower alkyl radical or a lower alkanoyl radical, n  is 3 or 4, and their lower alkyl esters and their salts with pharmaceutically acceptable bases.    Said compounds are useful as X-ray contrast media.