baber/WOPTO huggingface dataset:
Patent WO-2019010304-A1 (WO)
Title: Mineral coated microparticles for gene delivery in chronic wound therapy
Inventor: MURPHY WILLIAM L
IPC: A61K38/02
Filed: 2018-07-05
Abstract: Disclosed are formulations for providing a therapeutic bioactive polypeptide to injured tissue. Formulations include mineral coated microparticles wherein a polynucleotide is adsorbed to the mineral layer. Other formulations include a carrier including mineral coated microparticles wherein mineral coated microparticles include a polynucleotide. Also disclosed are methods for sustained delivery of a bioactive polypeptide and methods for treating chronic wounds using a formulation for providing sustained delivery of the bioactive peptide.
Patent WO-2019010318-A1 (WO)
Title: Inverting thrombectomy apparatuses and methods
Inventor: WALLACE MICHAEL
IPC: A61B17/221
Filed: 2018-07-05
Abstract: A mechanical thrombectomy apparatus for removing a clot from a vessel includes an elongate inversion support catheter having a distal end opening, an elongate puller extending within the support catheter, and a knitted tractor tube (501) extending over an outer surface of the support catheter, inverting into the distal end opening of the support catheter, and attached to the elongate puller at a first end within the support catheter, wherein the portion of the knitted tractor tube extending over the support catheter comprises a wire forming a helical spiral of alternating teardrop shaped-links (503) each having a rounded apex, wherein each link is connected to two adjacent links so that the apex of each link is on an outward-facing surface of the tractor tube, wherein the links flare outward from an outer wall of the support catheter when the puller is pulled proximally within the support catheter.
Patent WO-2019014288-A1 (WO)
Title: Structures and methods for capacitive isolation devices
Inventor: TUNCER ENIS
IPC: H01L23/538
Filed: 2018-07-11
Abstract: Described examples include a packaged device (100) including a first object (101) and a second object (102) spaced from each other by a gap (110). Each object has a first surface (101a, 102a) and an opposite second surface (101c, 102c). The first surfaces (101a, 102a) include first terminals (101b, 102b). A structure (120) includes at least two conductors (121) embedded in a dielectric casing (130) consolidating a configuration and organization of the at least two conductors (121). The at least two conductors (121) have end portions un-embedded by the dielectric casing (130). An end portion of at least one of the at least two conductors (121) is electrically connected to a first terminal (101b) of the first object (101), and an opposite end portion of the at least one of the at least two conductors (121) is electrically connected to a respective first terminal (102b) of the second object (102). The at least two conductors (121) electrically connect the first object (101) and the second object (102).
Patent WO-2019028326-A1 (WO)
Title: Leak-proof container lid with foam insulation
Inventor: HARRIS JAMISON
IPC: A47G19/22
Filed: 2018-08-03
Abstract: A container lid includes: a lid housing having a hollow body, an opening formed therethrough, and a thread pattern formed thereon for mating the container lid to a container; a closure mechanism coupled to the lid housing and operable to reversibly seal the opening; and foam insulation disposed within the hollow body.
Patent WO-2019032402-A1 (WO)
Title: Channel reservation signal in nr shared spectrum
Inventor: LEI JING
IPC: H04W74/08
Filed: 2018-08-03
Abstract: Methods, systems, and devices for wireless communication are described. A transmitting device may obtaining channel access after a clear channel assessment (CCA) operation. The transmitting device may then determine an offset between a boundary of a symbol and a particular time at which the channel access is obtained. The transmitting device may generate a channel reservation (CR) preamble based on the offset and transmit the CR preamble. The transmitting device may also generate the CR preamble based on occupancy of sub-bands or beams used by the transmitting device. A receiving device may monitor for a CR message based on the CR preamble.
Patent WO-2019046390-A1 (WO)
Title: Articles of footwear and other foot-receiving devices
Inventor: COOPER AARON
IPC: A43C1/04
Filed: 2018-08-29
Abstract: Footwear (100) or other foot-receiving devices include various conforming fit, stability, and/or "locked down" feel features. The uppers (102) for such articles of footwear (or other foot-receiving devices) include: (a) an upper shell (110) defining an interior chamber (110C), wherein the upper shell (110) includes a plantar support surface (110S) and sidewalls (110L, 110M) extending from an outer perimeter (110P) of the plantar support surface (110S); and (b) a bootie component (120) (e.g., formed as a sock or sock-like garment) received in the interior chamber (110C), The uppers may include: (c) one or more foot wrapping bands (200, 250, 252, 254, 256, 258, 260, 270, 272, 274, 276, 278, 280); and/or (d) an interior midsole (140) within the bootie component (120). The bootie component (120) is secured to the upper shell (110) at a location inside an outer perimeter (110P) of the plantar support surface (110S) of the upper shell (110). The foot wrapping band(s) (200, 250, 252, 254, 256, 258, 260, 270, 272, 274, 276, 278, 280) may be secured to the upper shell (110) at a location inside the outer perimeter (110P) of the plantar support surface (110S) of the upper shell (110).
Patent WO-2019051446-A1 (WO)
Title: Multi-pump memory system access circuits for sequentially executing parallel memory operations
Inventor: NGUYEN HOAN
IPC: G11C7/10
Filed: 2018-09-11
Abstract: Multi-pump memory system access circuits for sequentially executing parallel memory operations in a memory system are disclosed. A memory system includes a plurality of memory bit cells in a memory array. Each memory bit cell is accessible at a corresponding memory address used by memory read and write operations. The memory system includes ports at which a memory read or a memory write operation is received from a processor in each cycle of a processor clock. To increase memory bandwidth of the memory system without increasing the number of access ports of the memory array within the memory system, a double-pump memory system access circuit double-pumps (i.e., time-multiplexes) the access ports of memory array, effectively doubling the number of ports of the memory array. The double-pump memory system access circuit performs sequential accesses to a port of a memory cell in a memory array within a processor clock period.
Patent WO-2019060343-A1 (WO)
Title: Sealless downhole system with magnetically supported rotor
Inventor: MCMULLEN PATRICK
IPC: H02K7/09
Filed: 2018-09-19
Abstract: An electric stator surrounds a rotor and is configured to cause the rotor to rotate or generate electricity in the electric stator when the rotor rotates. The electric stator is spaced from the rotor and defines a first annular fluid gap in-between that is in fluid communication with an outside environment exterior the electric machine. A radial bearing includes a first portion coupled to the rotor and a second portion coupled to the electric stator. The first portion is spaced from the second portion defining a second annular fluid gap in-between that is in fluid communication with the outside environment exterior the electric machine.
Patent WO-2019060623-A1 (WO)
Title: Method for preparation of n-acetyl cysteine amide and derivatives thereof
Inventor: WALL G
IPC: C07C319/06
Filed: 2018-09-20
Abstract: The present invention includes methods for making and isolating N-acetylcysteine amide, intermediates and derivatives thereof comprising: contacting cystine with an alcohol and a chlorinating reagent to form an organic solution containing L-cystine dimethylester dihydrochloride; combining dried or undried L-cystine dimethylester dihydrochloride with a triethylamine, an acetic anhydride, and an acetonitrile to form a di-N-acetylcystine dimethylester; mixing dried di-N-acetylcystine dimethylester with ammonium hydroxide to form a di-N-acetylcystine amide; and separating dried di-N-acetylcystine dimethylester into N-acetylcysteine amide with dithiothreitol, triethylamine and an alcohol.
Patent WO-2019067320-A1 (WO)
Title: Reclosable packaging including a reclosable film and method of making the same
Inventor: KALIHARI VIVEK
IPC: B65D33/20
Filed: 2018-09-21
Abstract: A reclosable package (600) includes a container (602) having an elongate closure region (610) proximate to one edge (608) of the container and bounded on both ends by edge seal regions (620). The closure region includes a reclosable film (630) that seals the container proximate to the edge of the container and has an initial opening strength less than a seal strength of the edge seal regions. Application of an opening force to the reclosable film that is greater than the initial opening strength of the reclosable film may be operable to separate the reclosable film and expose a first reclose surface and a second reclose surface. Contact of the first reclose surface with the second reclose surface and application of a pressure to the reclosable film may be operable to re-adhere the first reclose surface and second reclose surface at a reclose strength.
Patent WO-2019079354-A1 (WO)
Title: Lan cable conductor energy measurement, monitoring and management system
Inventor: MEI RICHARD
IPC: G01K13/00
Filed: 2018-10-16
Abstract: A LAN cable conductor monitoring system includes an IoT device with a number of IoT input ports that are each connected to a network switch output port. The IoT device measures the current passing through each connected network switch output port, and passes the signals on to their respective cable conductors. A number of temperature sensors positioned at various points on the pass temperature readings back to the IoT device. If the temperature readings or current readings for a given network switch output port exceed predefined limits, the IoT device imposes PoE (Power over Ethernet) current constraints on the network switch.
Patent WO-2019084002-A1 (WO)
Inventor: LIDDELL WILLIAM
IPC: G06F3/048
Filed: 2018-10-23
Abstract: L'invention concerne une interface utilisateur graphique (GUI) tactile qui peut comprendre un écran tactile configuré pour afficher une interface utilisateur graphique comprenant un agencement d'un ou de plusieurs gadgets logiciels virtuels, chaque gadget logiciel virtuel ayant une forme et comprenant un ou plusieurs éléments d'interface utilisateur affichés par l'intermédiaire de l'interface utilisateur graphique. L'agencement du ou des gadgets logiciels virtuels est configurable. Un microcontrôleur peut être configuré pour détecter un toucher au niveau de l'écran tactile, identifier un gadget logiciel virtuel correspondant au toucher, et initier une action consistant (a) à commander un actionneur pour fournir une rétroaction haptique au niveau d'une zone de l'écran tactile sur laquelle le gadget logiciel virtuel identifié est affiché et/ou (b) à commander un dispositif électronique associé au système d'interface utilisateur.
Patent WO-2019084390-A1 (WO)
Title: Brake tester with tire tread profile measurement attachment
Inventor: TRACY ROGER
IPC: G01L5/28
Filed: 2018-10-26
Abstract: A drive-over brake tester includes an attachment for measuring the profile of the tires of the vehicle on the brake tester. The tire profile measuring apparatus does not interfere with the operation of the brake tester but quickly, makes at least one measurement of the tread profile of each tire across the tire running surface at least one point on the circumference of the tire and provides its measurement and analysis along with brake information.
Patent WO-2019089855-A1 (WO)
Inventor: LEE SARAH Y
IPC: C07K14/725
Filed: 2018-10-31
Abstract: La présente invention concerne des procédés de modification génétique de lymphocytes T, tels que des lymphocytes T CD4+, destinés à être utilisés en thérapie cellulaire. Selon certains aspects, les procédés selon l'invention comprennent une ou plusieurs étapes pour incuber les cellules dans des conditions de stimulation, introduire un polypeptide recombinant dans les cellules par transduction ou transfection, et cultiver les cellules dans des conditions favorisant la prolifération et/ou l'expansion. Selon certains aspects, l'incubation et/ou la culture sont réalisées en présence d'IL -2 recombinante. Selon certains aspects, les procédés selon l'invention sont un moyen efficace et fiable de produire des lymphocytes T génétiquement modifiés avec un taux élevé de réussite.
Patent WO-2019104332-A1 (WO)
Inventor: MONTOYA JAMES
IPC: E21B21/00
Filed: 2018-11-27
Abstract: L'invention concerne un ensemble de carottage souterrain pouvant comprendre un corps ayant au moins une paroi qui forme une cavité, la cavité ayant une extrémité supérieure et une extrémité inférieure. L'ensemble de carottage souterrain peut également comprendre un premier dispositif de régulation d'écoulement disposé de façon mobile à l'intérieur de la cavité, le premier dispositif de régulation d'écoulement étant configuré pour se déplacer d'une première position par défaut à une première position à l'intérieur de la cavité sur la base de premières caractéristiques d'écoulement de fluide qui s'écoule dans l'extrémité supérieure de la cavité vers l'extrémité inférieure de la cavité.
Patent WO-2019113452-A1 (WO)
Title: Système, procédé et dispositif de fourniture de notifications dans une communication de groupe
Inventor: LIU XIUJUAN
IPC: H04M3/56
Filed: 2018-12-07
Abstract: La présente invention concerne un procédé, un dispositif et un système pour une communication en groupe. Le procédé comprend l'obtention, par un ou plusieurs processeurs, d'un contenu d'entrée à partir d'une interface de session de communication, le contenu d'entrée comprenant un ou plusieurs identifiants d'instruction de notification individuelle et des informations de caractéristiques de membres, la détermination, par le ou les processeurs, d'un ou de plusieurs membres de groupe parmi un groupe prédéfini, le ou les membres de groupe étant déterminés sur la base, au moins en partie, des informations de caractéristiques de membres, et l'ajout, par le ou les processeurs, d'informations d'instruction de notification individuelle pour le ou les membres de groupe déterminés à l'interface de session de communication.
Patent WO-2019118439-A1 (WO)
Title: Module de capteur de matière particulaire optique miniature
Inventor: FENG CHEN
IPC: G01N21/47
Filed: 2018-12-11
Abstract: Des modes de réalisation de l'invention comprennent un module de capteur de PM optique miniature. Un module de capteur de matière particulaire optique miniature peut comprendre un boîtier ; un générateur de micro-flux d'air positionné à l'intérieur du boîtier ; un actionneur positionné adjacent au générateur de micro-flux d'air et conçu pour entraîner le générateur de micro-flux d'air ; un ensemble carte de capteur de matière particulaire miniature en communication fluidique avec le générateur de micro-flux d'air ; et un ensemble câble souple conçu pour se fixer au boîtier et/ou à l'ensemble carte de capteur de matière particulaire miniature.
Patent WO-2019118887-A1 (WO)
Title: Procédé et système de matériau additif en boucle ouverte pour créer un environnement habitable par les humains
Inventor: TOMPKINS DANIEL
IPC: B33Y99/00
Filed: 2018-12-14
Abstract: L'invention concerne des procédés de production de polymères à base d'hydrocarbure et de structures polymères à base d'hydrocarbure qui sont capables d'éliminer le dioxyde de carbone d'un environnement ambiant pour produire de l'oxygène respirable. Les procédés produisent des structures polymères enfermées, exposées à l'énergie solaire, capables de se développer dans une zone par la réutilisation d'au moins une partie des polymères à base d'hydrocarbure. En tant que tel, le procédé produit des structures polymères/à base d'hydrocarbure autonomes capables de collecte et de réutilisation de ressources in situ pour créer une zone habitable durable. Les procédés peuvent être utilisés pour créer un environnement habitable dans des conditions par ailleurs difficiles, telles que celles associées à des concentrations élevées de dioxyde de carbone et de basse pression, sans qu'il soit nécessaire d'utiliser des ressources non renouvelables externes, et en utilisant à la place des ressources renouvelables in situ pour améliorer la viabilité d'habitation dans l'environnement des structures tridimensionnelles fabriquées.
Patent WO-2020142075-A1 (WO)
Inventor: LOPES PEREIRA VITOR
IPC: E21B41/00
Filed: 2018-12-31
Abstract: Predicting the efficiency of downhole mechanical removal of one or more accreted materials from one or more wellbore walls may prevent the unnecessary consumption of resources in a wellbore fluids displacement operation. A method and system for removing accreted materials in a wellbore is provided, wherein the efficiency of mechanical removal of accreted materials may be characterized based, at least in part, on a comparison between one or more actual shear stresses exerted by a wellbore servicing fluid at one or more depths of the wellbore and one or more required shear stresses to remove the accreted materials from the depth. The one or more required shear stresses may be determined using one or more of one or more known properties of the one or more accreted materials, one or more rheology models, one or more hydraulic parameters, one or more wellbore hydraulic models, and one or more downhole conditions. To account for one or more effects of eccentricity in the wellbore, the one or more actual shear stresses exerted by wellbore servicing fluid may be determined by partitioning one or more three dimensional flow profiles into divided annular segments for individual analysis. To improve operational decision making, operators or automated processes may modify the wellbore fluids displacement operation based, at least in part, on the comparison. The comparison between the one or more actual shear stresses and the one or more required shear stresses may be used to generate a parameter that characterizes the cleaning efficiency of the wellbore fluids displacement operation.
Patent WO-2019140023-A1 (WO)
Title: Combination therapy
Inventor: COSKUN TAMER
IPC: A61K38/22
Filed: 2019-01-10
Abstract: The disclosure describes a combination therapy for treating diabetes or chronic kidney disease by administering to an individual in need of such treatment an effective amount of a urocortin-2 compound (or a pharmaceutically acceptable salt thereof) with a MC4R agonist (or a pharmaceutically acceptable salt thereof), and to methods of using the same to treat diabetes or chronic kidney disease.
Patent WO-2019147951-A1 (WO)
Title: Secure dispute settlement system
Inventor: HOROWITZ MICHAEL
IPC: G06F21/62
Filed: 2019-01-25
Abstract: A secure dispute settlement system is described. The secure dispute settlement system may receive first injury data associated with first injuries of an injured party. The secure dispute settlement system may identify, based on the first injury data, historical settlement data associated with a historical settlement. The historical settlement data may indicate second injury data associated with second injuries that are similar to the first injuries, and a value that the second injuries were settled for. The secure dispute settlement system may generate, based on the historical settlement, a settlement report that indicates an estimated fair value for the first injuries.
Patent WO-2019152778-A1 (WO)
Title: Multifunctional track system with independently moveable vehicles
Inventor: SALMON CARL ANTHONY
IPC: E01B25/26
Filed: 2019-02-01
Abstract: A multifunctional track system with two or more independently movable trolleys which can run along the track system and are adapted to receive multiple interchangeable components for data collection, navigation, and cargo transportation is disclosed. The trolleys and the track system communicate data to a central station, which monitors and sends instructions to the trolleys. The system can have horizontal, vertical or angular segments and the trolleys are enabled to move along all segments and switch between tracks. Various operational units in the trolleys are possible in the same system.
Patent WO-2019157146-A1 (WO)
Title: Alpha polyglutamated antifolates and uses thereof
Inventor: NIYIKIZA CLET
IPC: C07K16/28
Filed: 2019-02-07
Abstract: The disclosure relates generally to alpha polyglutamated Antifolates, formulations containing liposomes filled with alpha polyglutamated Antifolates, methods of making the alpha polyglutamated Antifolates and liposome containing formulations, and methods of using polyglutamated alpha polyglutamated Antifolates and liposome containing formulations to treat hyperproliferative disorders ( e.g. , cancer) and disorders of the immune system ( e.g. , an autoimmune disease such as rheumatoid arthritis).
Patent WO-2020180319-A1 (WO)
Title: Collapsible vessel
Inventor: HOLLIS JOHN REY
IPC: A45F3/20
Filed: 2019-03-06
Abstract: A collapsible vessel (10) reconfigurable between expanded and collapsed configurations. A sleeve combination (12) has an inner sleeve (16) rotatable relative to an outer sleeve (14). A liner (18) is retained by the sleeve combination (12). The sleeves (14, 16) have opposed major walls (44, 46, 52, 54) divided by opposed fold line formations (45, 49, 53, 57). Arrays of flexion apertures (66, 68) span a lateral range from adjacent to the respective fold line formation (45, 49, 53, 57) toward a central portion of the major wall (44, 46, 52, 54), and an aperture density can vary generally based on distance from the fold line formation (45, 49, 53, 57) to promote a true-round confirmation of the expanded vessel (10). A lid structure (28) with a disk (30) and opposed retaining tabs (36) can be selectively engaged with the liner (18), and a retaining strap (20) can be pivotally coupled to the sleeve combination (12) with a first orientation encircling the sleeve combination (12) and a second, longitudinal orientation. A storage bag (70) with first and second longitudinally-disposed stays (82, 84) can receive and further compress the vessel (10).
Patent WO-2019173605-A1 (WO)
Title: Ethylene-propylene branched copolymers as viscosity modifiers with enhanced fuel economy
Inventor: ZHANG JINGWEN
IPC: C08F210/16
Filed: 2019-03-07
Abstract: In some embodiments, ethylene-propylene branched copolymers are synthesized with pyridyldiamido catalysts and a chain transfer agent, and their performance as viscosity modifiers in oil are detailed. In some embodiments, the present disclosure provides for ethylene-propylene branched copolymers having a shear thinning onset of less than about 0.01 rad/s and an HTHS value of less than about 3.3. In some embodiments, the ethylene-propylene branched copolymer is used as a viscosity modifier in a lubricating composition and a fuel composition.
Patent WO-2019178484-A1 (WO)
Title: Novel methods
Inventor: SNYDER GRETCHEN
IPC: A61K31/4985
Filed: 2019-03-15
Abstract: The disclosure provides methods for the acute treatment of depression and/or anxiety, for the enhancement of mTOR (e.g., mTORC1) signaling, and for the reduction of neuroinflammation, comprising administering to a patient in need thereof, a therapeutically effective amount of a 5-HT 2A  or 5-HT 2A /D2 receptor ligand, e.g. lumateperone.