baber/WOPTO huggingface dataset:
Patent CA-2892623-C (CA)
Title: Paire de variants du domaine ch3 induisant la formation d'heterodimere de region constante de chaine lourde d'anticorps a haute efficacite, procede de preparation associe, et util isation associee
Inventor: KIM YONG SUNG
IPC: C07K16/46
Filed: 2013-11-27
Granted: 2020-08-11
Abstract: La présente invention concerne une paire de variants du domaine CH3 d'un anticorps, un procédé pour la préparation de celle-ci, et une utilisation associée, une mutation étant induite dans le domaine CH3 afin d'améliorer le rendement de formation d'une région constante de chaîne lourde d'hétérodimère d'un anticorps. L'hétérodimère de domaine CH3 selon la présente invention, forme une région constante de chaîne lourde d'hétérodimère à haute efficacité de 90 à 95 % ou plus et présente également une excellente thermostabilité. La région constante de chaîne lourde d'hétérodimère comprenant l'hétérodimère de domaine CH3 peut construire un anticorps monoclonal bispécifique qui reconnaît simultanément deux types d'antigènes. L'hétérodimère de domaine CH3 de la présente invention, et l'anticorps bispécifique ou protéine de fusion d'une région constante d'anticorps le comprenant peuvent être utilisés pour le traitement ou la prévention d'une maladie associée à un antigène cible ou une protéine cible.
Patent CA-2894298-C (CA)
Title: Composes de dihydroisoquinolinone substitue
Inventor: COLLINS MICHAEL RAYMOND
IPC: A61K31/4725
Filed: 2015-06-16
Granted: 2017-04-18
Abstract: Linvention concerne des composés de formule générale (I) (voir la formule I), où R1, R2, R3, R4, L, X et Z sont tels que définis aux présentes, et de sels pharmaceutiquement acceptables. Linvention vise des compositions pharmaceutiques comprenant de tels composés et sels ainsi que des méthodes dutilisation de tels composés, sels et compositions afin dinhiber lactivateur de lhomologue 2 de zeste (EZH2).
Patent CA-2894381-C (CA)
Inventor: OLIVARES ERIC
IPC: C12P19/34
Filed: 2013-12-06
Granted: 2021-01-12
Abstract: Methods for multiplex ligation-dependent probe amplification include (a) providing sample tissue containing different target nucleic acids, (b) providing different probe sets for each of the target nucleic acids, each probe set including a first locus specific probe having a first adapter sequence and a first target specific portion and a second locus specific probe having a second adapter sequence, and a second target specific portion adjacent to the first target specific portion, (c) hybridizing the probe sets to the target sequences to form hybridization complexes, (d) ligating the hybridization complexes to form ligated probes, (e) amplifying the ligated probes to form amplicons, and (f) detecting the amplicons in a detection system by sequencing each of the amplicons.
Patent CA-2900802-C (CA)
Title: Rebound device to facilitate hockey training
Inventor: KLANOW BRIAN
IPC: A63B69/00
Filed: 2015-08-18
Granted: 2023-01-17
Abstract: An illustrative example embodiment of a rebound device includes a rigid base that has end faces that establish a width of the base and side faces between the end faces. The side faces establish a base length. The length of the base is greater than its width. A resilient member has a first side surface secured to at least one of the side faces of the base. The resilient member has a thickness in a direction parallel to the width of the base between the first side and a second side of the resilient member that faces in an opposite direction from the first side. The second side of the resilient member presents a rebound surface for resiliently deflecting an object away from the resilient member.
Patent CA-2907632-C (CA)
Title: Pre-cooling system having controlled internal adjustment
Inventor: LANGEVIN STEPHANE
IPC: C21D1/667
Filed: 2014-04-01
Granted: 2020-04-14
Abstract: The invention relates to equipment for cooling a metal strip (2) having a liquid coating to be solidified, wherein said strip is continuously moving. Said equipment is characterized in that each half-cooler (11, 12) is divided, over the length thereof, into at least two sections, a first section (13) and a second section (14), in the direction of the movement of the strip (2). The first section (13) is separated from the second section (14) in each half-cooler (11, 12) by a respective internal adjustment device (7, 8), making it possible to change the gas flow/pressure parameter so that the value of said gas flow/pressure parameter is different in the first section (13) from the value of said parameter in the second section (14).
Patent CA-2908513-C (CA)
Inventor: BISHOP WEDITH BOB
IPC: E21B43/12
Filed: 2015-10-07
Granted: 2017-12-05
Abstract: A two-piece well plunger is provided having an upper sleeve and a lower lance member that engages (e.g., unites) and disengages the upper member. The upper and lower member are sized for receipt within production tubing of a well and are configured to move upwardly in the production tubing when united and to fall separately when disengaged (e.g., separated). The upper sleeve is generally cylindrical and has an central bore. The lower lance member includes a dislodging rod that is sized to extend through central bore of the upper sleeve when the two pieces are united. The lance member and rod seal the central bore when the members are united. An upper end of the rod extends beyond a top end of the sleeve when the members are united and is utilized to disengage the members when the united plunger arrives in a well head.
Patent CA-2908643-C (CA)
Inventor: VAN AKEN MICHIEL GIJSBERT
IPC: F25J1/02
Filed: 2014-04-08
Granted: 2021-05-18
Abstract: The present invention provides a method of liquefying a contaminated hydrocarbon-containing gas stream, the method comprising at least the steps of: (a) providing a contaminated hydrocarbon-containing gas stream (20); (b) cooling the contaminated hydrocarbon-containing gas stream (20) in a first heat exchanger (3) thereby obtaining a cooled contaminated hydrocarbon-containing stream (40); (c) cooling the cooled contaminated hydrocarbon- containing stream (40) in an expander (4) thereby obtaining a partially liquefied stream (70); (d) separating the partially liquefied stream (70) in a separator (5) thereby obtaining a gaseous stream (80) and a liquid stream (90); (e) expanding the liquid steam (90) obtained in step (d) thereby obtaining a multiphase stream (100), the multiphase stream (100) containing at least a vapour phase, a liquid phase and a solid phase; (f) separating the multiphase stream (100) in a separator (7) thereby obtaining a gaseous stream (110) and a slurry stream (120); (g) separating the slurry stream (120) in a solid/liquid separator (9) thereby obtaining a liquid hydrocarbon stream (170) and a concentrated slurry stream (140); (h) passing the gaseous stream (80) obtained in step (d) through the first heat exchanger (3) thereby obtaining a heated gaseous stream (270); and (i) compressing the heated gaseous stream (270) thereby obtaining a compressed gas stream (220); and (j) combining the compressed gas stream (220) obtained in step (i) with the contaminated hydrocarbon-containing gas stream (20) provided in step (a).
Patent CA-2909152-C (CA)
Title: Soufflante a registre integre ayant une etancheite a l'air amelioree
Inventor: PARK MUN SU
IPC: F04D25/14
Filed: 2014-04-22
Granted: 2018-08-21
Abstract: La présente invention porte sur une soufflante à registre intégré ayant une étanchéité à l'air améliorée. Selon la présente invention, une soufflante (100) est formé par l'assemblage des parties périphériques externes d'une enceinte de soufflante a (105) ayant un orifice d'aspiration (103) et d'une enceinte de soufflante b (106) sur le côté opposé à l'orifice d'aspiration à l'aide de plusieurs pièces saillantes d'assemblage d'enceinte. Une saillie d'arrêt d'aube (104b) est formée à la partie inférieure centrale d'un orifice d'évacuation (104), et une partie de boîtier de contact d'aube (107) est formée à la partie supérieure de l'orifice d'évacuation. Des parties de fixation à vis de moteur de registre (105a) font saillie d'un seul tenant à partir de la surface supérieure externe de la partie de boîtier de contact d'aube (107) adjacente à l'orifice d'évacuation de l'enceinte de soufflante a et de la surface adjacente au côté arrière de la partie supérieure d'un bâti de fixation (104a) de l'orifice d'évacuation. Un trou d'arbre de moteur de registre (105b) est percé sur la surface latérale de l'enceinte sur le côté de l'orifice d'aspiration d'une partie de saillie de trou d'arbre de moteur de registre (105b') qui est formée d'un seul tenant sur le côté supérieur externe de la partie de boîtier de contact d'aube au voisinage des parties de fixation à vis de moteur de registre (105a) de l'enceinte de soufflante a. Un arbre de rotation d'aube (106a) fait saillie à partir de la surface interne d'une partie de saillie de trou d'arbre de moteur de registre (105b") de l'enceinte de soufflante b faisant face à la partie de saillie de trou d'arbre de moteur de registre (105b') de l'enceinte de soufflante a. Un arbre de moteur de registre excentré (201a) d'un moteur de registre (201) est introduit dans le trou d'arbre de moteur de registre de l'enceinte de soufflante a pour assembler un support de fixation de moteur de registre (201b) faisant face au trou d'arbre de moteur de registre. Une aube (202b), pour ouvrir ou fermer l'orifice d'évacuation avec un élément, est assemblée sur l'arbre de moteur de registre (201a) et l'arbre de rotation d'aube (106a) sur la surface interne de la partie de saillie de trou d'arbre de moteur de registre. Un module d'aube (202), sur lequel un joint d'étanchéité (202a) est assemblé d'un seul tenant, est assemblé et installé de chaque côté de l'aube.
Patent CA-2914175-C (CA)
Inventor: KERSCHBAUMER ANDREAS
IPC: G07C9/00
Filed: 2015-12-07
Granted: 2018-02-13
Abstract: As part of the method for avoiding misuse of access authorisations of an ID-based access control system comprising at least one access control device (1, 1') and a central server (2), with which the at least one access control device (1, 1') can be connected for'the purposes of data communication, a data record is stored for each customer medium in a database of the central server (2), which data record contains at least one contact address of the rightful owner of the customer medium and the at least one customer medium ID, wherein during a first interaction between a customer medium and an access control device (1, 1') of the access control system access is granted for a valid access authorisation, and at the same time or within a specified configurable time span after the interaction a message is sent involving the data record stored in the central server (2) and the read-out customer medium ID to which the access authorisation is assigned, a message is sent to a contact address of the rightful owner of the customer medium requesting confirmation that he, the rightful owner, is currently using the customer medium, wherein as long as no confirmation is sent on the part of the rightful owner to a specified contact address of the access control system, any further entry via the access control devices (1, 1') of the access control system, and in the case of a post-payment scenario, the exit from the area covered by the access control system is refused. Figure
Patent CA-2915359-C (CA)
Inventor: MINOO KOOHYAR
IPC: H04N19/30
Filed: 2014-06-13
Granted: 2018-09-04
Abstract: In one embodiment, a method receives a plurality of sample values. The method then determines a filter to determine an up-sampled value for a first layer for a video, wherein the filter has a set of coefficient values of [-1, 3, -9, 47, 31, -10, 4, -1] or [-1, 4, -10, 31, 47, -9, 3, -1]  as-signed to the filter. The up-sampled value is determined by applying the set of coefficient values of [-1, 3, -9, 47, 31, -10, 4, -1] or [-1, 4, -10, 31, 47, -9, 3, -1] to the plurality of sample values. The method then outputs the up-sampled value for use in coding a second layer of a higher resolution than the first layer. The up-sampled values may be for the 6/16 and -6/16 phase offsets.
Patent CA-2919575-C (CA)
Inventor: WILD MICHAEL
IPC: B05D1/28
Filed: 2016-02-02
Granted: 2019-09-24
Abstract: The present invention relates to a method for the application of an aqueous treatment solution to the surface of a strip (1) which is moving at a preset trip speed, comprising the following steps: spraying the aqueous treatment solution onto at least one rotating roll (21, 22) of a roll coater (20) by means of rotary sprayer (2) having a plurality of spray rotors (3) disposed side by side in the longitudinal direction of the roll (21, 22), to which the aqueous treatment solution is supplied and which are made to rotate by a spray rotor drive so that the treatment solution, driven by the centrifugal force, is sprayed in the form of a spray jet onto the surface of the roll (21, 22), and applying the aqueous treatment solution to at least one surface of the strip (1) by moving the strip (1) past a rotating application roll (21) of the roll coater (20), with the application roll (21) transferring the aqueous treatment solution in the form of a wet film onto the surface of the strip (1). In addition, the present invention also relates to an application device comprising a roll coater (20) and a rotary sprayer (2) as well as to a system for carrying out the method. (Figure 2)
Patent CA-2921291-C (CA)
Inventor: ANDERSSON PATRIK
IPC: F04D15/00
Filed: 2014-08-06
Granted: 2021-06-15
Abstract: L'invention concerne un ensemble de turbine et une pompe pour pomper un liquide, comprenant une chambre d'aspiration et une turbine (4) disposée pour tourner dans ladite chambre d'aspiration, ladite turbine étant suspendue dans une extrémité inférieure (5) d'une unité d'arbre d'entraînement (6) s'étendant en sens axial, ladite extrémité inférieure (5) de l'unité d'arbre d'entraînement (6) étant reçue dans un dégagement de forme cylindrique (10) de la turbine (4), la turbine (4) étant déplaçable vers l'arrière et vers l'avant dans la direction axiale par rapport à l'unité d'arbre d'entraînement (6). La turbine comprend en outre un trou s'étendant en sens axial (21) qui relie le dégagement de forme cylindrique (10) et la chambre d'aspiration et l'unité d'arbre d'entraînement (6) comprend une goupille s'étendant en sens axial (22) qui fait saillie de ladite extrémité inférieure (5) de l'unité d'arbre d'entraînement (6), ladite goupille (22) étant disposée dans ledit trou (21).
Patent CA-2922363-C (CA)
Inventor: CHRISTIANSEN DAVE
IPC: G06F21/62
Filed: 2014-09-03
Granted: 2021-10-26
Abstract: The technology includes a method to test what information an application transfers to an external computing device. A user's consent is explicitly obtained before the application transfers certain types of information, such as sensitive information. When a determination is made that an application is transferring sensitive information, a prompt for consent from a user may be provided that is accurate and detailed. In pre-production environments, technology can be used to detect whether this sensitive information is being transferred, and to validate whether a prompt for consent is necessary or unnecessary. To determine this, shimming is used to intercept application calls to APIs that return sensitive information. Requested sensitive information may be substituted with recorded or forged information from those APIs to produce a sentinel or canary. Similarly, network traffic of the application may be analyzed by another shim to determine when the substitute information is present.
Patent CA-2926121-C (CA)
Title: Rotary union for automatic tire inflation system
Inventor: HENNIG MARK KEVIN
IPC: B60C23/00
Filed: 2014-10-23
Granted: 2019-09-24
Abstract: A rotary union for a tire inflation system may comprise a stator and a rotor assembly, and may he contained entirely within the space formed by a hubcap and wheel end. T he rotor assembly may be mounted to the interior of a hubcap. The rotor assembly may comprise a tube that extends into the stator. The tube may be sealed in the rotor assembly by a first annular seal, and may be sealed in the stator by a second annular seal.
Patent CA-2926150-C (CA)
Title: Binder composition and coating composition made thereof
Inventor: CAI QIAOQIAO
IPC: C08L31/04
Filed: 2013-10-10
Granted: 2021-02-16
Abstract: A new binder composition comprising, by dry weight based on the total dry weight of the binder composition, i) from 93% to 99.96% of polymer particles comprising, as polymerized units, by dry weight based on the total weight of the polymer particles, from 25% to 95% of a vinyl acetate; and from 5% to 75% of a vinyl ester of versatic acid and/or a vinyl ester of 2-ethyl hexanoic acid; and ii) from 0.04% to 7% of a low water soluble cyclodextrin.
Patent CA-2928148-C (CA)
Title: Procede d'hydrostannation trans-selective d'alcynes par catalyse au ruthenium
Inventor: FURSTNER ALOIS
IPC: C07F7/22
Filed: 2014-10-14
Granted: 2020-10-13
Abstract: L'invention concerne un procédé d'hydrostannation trans-sélective d'alcynes par catalyse au ruthénium, et les produits ainsi obtenus. Le procédé de l'invention met en oeuvre un hydrure d'étain mis en réaction avec un alcyne, en présence d'un catalyseur de ruthénium coordonné par cyclopentadiényle.
Patent CA-2938446-C (CA)
Inventor: KASHFI KHOSROW
IPC: A01N3/00
Filed: 2015-02-11
Granted: 2022-04-26
Abstract: La présente invention concerne un procédé permettant de réduire les lésions cellulaires d'une plante en traitant ladite plante avec un composé contenant une fraction de libération de NO et une fraction de libération de H2S liée de manière covalente à un noyau dérivé de l'aspirine ou à un composé NOSH. Lesdits composés peuvent également être utilisés dans un procédé d'amorçage d'une plante contre des facteurs de stress abiotique, et dans un procédé de stimulation de la croissance des plantes.
Patent CA-2939204-C (CA)
Inventor: GAUTHIER LAURENT
IPC: C07K16/28
Filed: 2015-03-12
Granted: 2023-06-27
Abstract: La présente invention concerne des anticorps ayant une stabilité améliorée. L'invention concerne notamment des anticorps capables de se lier à des polypeptides du KIR3DL2. Les anticorps sont adaptés au traitement de troubles caractérisés par des cellules exprimant le KIR3DL2, en particulier les lymphocytes T CD4+, y compris de malignités telles que le mycosis fongoïde et le syndrome de Sézary, et de troubles auto-immuns exprimant le KIR3DL2.
Patent CA-2942787-C (CA)
Title: Cleaning solution and methods of cleaning a turbine engine
Inventor: TIBBETTS NICOLE JESSICA
IPC: C23G1/02
Filed: 2016-09-22
Granted: 2019-11-19
Abstract: A cleaning solution for a turbine engine includes water between 68.65 percent and 99.63 percent by volume of the cleaning solution; a first organic acidic component between 0.1 percent and 15 percent by volume of the cleaning solution; a second organic acidic component between 0.1 percent and 15 percent by volume of the cleaning solution;  isoropylamine sulphonate between 0.07 percent and 0.14 percent by volume of the cleaning solution; alcohol ethoxylate between 0.035 percent and 0.07 percent by volume of the cleaning solution; triethanol amine between 0.035 percent and 0.07 percent by volume of the cleaning solution; sodium lauriminodipropionate between 0.03 percent and 1.0 percent by volume of the cleaning solution. The cleaning solution has a pH value between 2.5 and 7Ø A method of cleaning a turbine engine includes directing a cleaning solution towards a component of the turbine engine having a layer of foreign material thereon.
Patent CA-2951145-C (CA)
Title: Page constructor and page constructing method
Inventor: DONG AIQIANG
IPC: G06F40/00
Filed: 2016-12-08
Granted: 2019-01-15
Abstract: A page constructor and a page constructing method are provided. The page constructor includes: a dragging instruction module, for identifying a dragging operation, generating a dragging instruction, dragging a widget to a newly-established form page and transferring a program file to a corresponding database; an adjusting instruction module, for identifying a modification operation, obtaining a modified positional coordinate parameter of the widget, generating an adjusting instruction, adjusting a size and a position of the widget and modifying a positional coordinate parameter of the widget; a widget library, for storing a page layout widget and a page element widget; a data model base, for configuring a table and create an sql statement; and a data binding module, for binding table field attributes of the database, generating page constructing data and storing the same by an XML structure, which reduces complexity of page construction and improves constructing experience of users.
Patent CA-2952587-C (CA)
Inventor: ROTSAERT CHRISTOPHER
IPC: G06Q20/34
Filed: 2015-07-10
Granted: 2022-09-06
Abstract: L'invention concerne un procédé de gestion d'une transaction mise en uvre par un terminal de paiement électronique (10) présentant un lecteur de piste magnétique pour la lecture d'une carte de paiement d'un utilisateur (U), comprenant les étapes suivantes, dans un serveur distant sécurisé (12) :  réception (20), en provenance dudit terminal de paiement électronique (10), d'un message de transaction, portant une donnée de ladite carte, lue par ledit lecteur de piste magnétique et chiffrée par ledit terminal de paiement électronique (10), et un identifiant d'un terminal de communication mobile (11) dudit utilisateur (U);  émission (21), à destination dudit terminal mobile (11), d'un message de requête de validation de transaction, portant une information de ladite transaction;  réception (22), en provenance dudit terminal mobile (11), d'un message de validation portant une réponse audit message de requête de validation;  gestion (23) de ladite transaction.
Patent CA-2953612-C (CA)
Inventor: VAN STENSEL JONATHAN PAUL
IPC: B64D47/00
Filed: 2017-01-05
Granted: 2019-05-14
Abstract: Systems and methods for providing an efficient and configurable port interface in an avionics data transfer system (100) are provided. For instance, in one embodiment a set of virtual ports associated with an avionics data transfer system (100) can be defined. At least as a subset of the virtual ports can be mapped to one or more addresses (402) in a memory space associated with the data transfer system (100), such that each virtual port has a fixed definition in the memory space. One or more of the virtual ports can then be associated with one or more physical ports (308) associated with an interface between a host computing device (202) and an end system (200) in the data transfer system (100) by specifying for the one or more virtual ports a plurality of port parameters that define the respective one or more physical ports (308).
Patent CA-2954377-C (CA)
Inventor: HOLSON BENJAMIN MICHAEL
IPC: G06Q50/30
Filed: 2015-06-12
Granted: 2017-07-11
Abstract: A social networking system maintains a limited user profile associated with a user of the social networking system who does not satisfy one or more criteria for the social networking system to maintain a user profile. The limited user profile includes information describing the user and allows the user to be associated with limited types of interactions with the social networking system. An administrator is associated with the limited user profile and may modify information associated with the limited user profile as well as authorize or deny interactions involving the limited user profile. When the user satisfies criteria for the social networking system maintaining a user profile, the social networking system generates a user profile based on information in the limited user profile and prior interactions involving the limited user profile.