baber/WOPTO huggingface dataset:
Patent WO-2022016109-A1 (WO)
Title: Inflation hub for a fluid inflatable apparatus
Inventor: FRANKLIN CURTIS
IPC: F16K5/00
Filed: 2021-07-16
Abstract: An inflation hub includes a body having an internal lumen defining first and second lumen sections. A stopcock valve has a stem extending from the body between the first and second lumen sections, the stem being selectively rotatable between an open position, wherein an internal channel thereof fluidly connects the first and second lumen sections together, and a closed position, wherein the stopcock valve fluidly disconnects the first and second lumen sections from one another. A pressure-relief valve is integrated within the stem of the stopcock valve and in fluid communication with the internal channel thereof, and includes a loading member biasing the pressure-relief valve into a closed position. The pressure-relief valve moves into an open position when the stopcock valve is in the open position thereof and a pressure with the internal lumen of the body exceeds a threshold, opening pressure of the loading member.
Patent WO-2022020714-A1 (WO)
Inventor: ODINGO JOSHUA
IPC: A61P1/16
Filed: 2021-07-23
Abstract: La présente invention concerne des inhibiteurs de HSD17B13 et des compositions pharmaceutiques comprenant lesdits inhibiteurs. Les composés et compositions de l'invention sont utiles pour le traitement d'une maladie hépatique, d'une maladie métabolique ou d'une maladie cardiovasculaire, telle que la NAFLD ou la SHNA, ou la lésion hépatique induite par les médicaments (DILI).
Patent WO-2022026577-A1 (WO)
Inventor: GARBÁN HERMES
IPC: A61K39/00
Filed: 2021-07-28
Abstract: Compositions and methods for eradicating tumor cells using novel compositions are contemplated. In one aspect, a pharmaceutical composition comprising a CAR scaffold and an antigen binding domain in a single chimeric species is provided. In some aspects, the CAR scaffold may comprise a CD28 costimulatory signaling region and a CD3ζ activation domain or a complete CD3ζ activation domain. In some aspects, the CAR scaffold may be codon-optimized for improved expression in mammalian cell lines and/or for improved function upon transfection into natural killer (NK) or other immune cells. In further aspects, the antigen binding domain may comprise a VL and VH domain linked by a spacer and may be codon optimized. A CD64 leader sequence may be attached to the antigen binding domain,  e.g ., at the N-terminus of the antigen binding domain.
Patent WO-2022066279-A1 (WO)
Inventor: MALEEV IVAN
IPC: G01N21/53
Filed: 2021-07-29
Abstract: Techniques herein include an apparatus and method for measuring and monitoring properties of fluids consumed in a semiconductor fabrication process. The apparatus includes a flow cell having a hollow chamber, a first chamber sidewall of the hollow chamber bisecting the length of the flow cell, the first chamber sidewall having a predetermined angle to the incoming direction of light from the first light source; a refractive index sensor configured to detect the light from the first light source transmitted through the hollow chamber of the flow cell and exiting the flow cell through the second flow cell sidewall of the at least six flow cell sidewalls; and a first light sensor configured to detect the light from the first light source scattered off the fluid in the hollow chamber.
Patent WO-2022035611-A1 (WO)
Title: Dispositif à écoulement latéral pour la détection d'anticorps sars-cov-2 dans des échantillons humains et animaux
Inventor: LIZER JOSHUA
IPC: G01N33/543
Filed: 2021-07-30
Abstract: L'invention concerne un dispositif à écoulement latéral et des méthodes pour la détection d'anticorps dirigés contre le syndrome respiratoire aigu sévère lié au coronavirus 2 (SARS-CoV-2) dans un échantillon de fluide corporel d'un animal ou d'un être humain. Les méthodes de test comprennent la mise en contact de l'échantillon avec un conjugué comprenant un antigène de protéine de spicule de SARS-CoV-2 recombinant qui a été conjugué à un agent de détection, un complexe antigène-anticorps étant formé entre le conjugué d'antigène de protéine de spicule du SARS-CoV-2 et les anticorps du SARS-CoV-2 présents dans l'échantillon; la capture du complexe antigène-anticorps formé avec une molécule de liaison Fc; et la détection du complexe capturé.
Patent WO-2022081238-A1 (WO)
Inventor: SHUKLA AMIT
IPC: H04W52/02
Filed: 2021-08-06
Abstract: Disclosed herein are related to coordinating communication among a first access point, a first station device, a second access point, and a second station device. In one aspect, the second access point receives, from the first access point, a first beacon of the first access point at a first beacon transmission time. The first beacon may indicate an offset between the first beacon transmission time of the first beacon and a first data transmission time of the first access point for communication between the first access point and a first station device. In one aspect, the second access point may determine, according to the offset, a second data transmission time of the second access point to be distinct from the first data transmission time of the first access point. The second access point may communicate with a second station device, according to the second data transmission time.
Patent WO-2022046633-A1 (WO)
Title: Covid-19 vaccines with tocopherol-containing squalene emulsion adjuvants
Inventor: ANOSOVA NATALIE
IPC: A61P31/14
Filed: 2021-08-23
Abstract: Provided are novel vaccines for prophylactic treatment of SARS-CoV-2 infections and COVID-19 and methods of making the vaccines, wherein the vaccines contain an oil-in-water emulsion comprising tocopherol and squalene.
Patent WO-2022051563-A1 (WO)
Inventor: ARSENEAU PAUL
IPC: G01M15/00
Filed: 2021-09-03
Abstract: A fuel injector testing machine is provided. The machine includes a head unit having a flow meter, and a fuel injector holding assembly. The head unit and/or the fuel injector holding assembly can be moved relative to each other, allowing the head unit to test a subset of fuel injectors held on the fuel injector holding assembly, and subsequently can test another subset of the fuel injectors via movement of the head unit and/or fuel injector holding assembly.
Patent WO-2022051579-A1 (WO)
Title: System and method for crystal-to-channel coupling
Inventor: LABELLA ANDREW
IPC: G01T1/202
Filed: 2021-09-03
Abstract: A multiplexing scheme, a system for reading out signals from an optical sensor array, particle detection devices and systems are provided. For example, the optical sensor array may comprise plurality of optical sensors arranged in rows and columns. In the multiplexing scheme, a readout ASIC may be electrically connected to the plurality of optical sensors via a plurality of first channels and a plurality of second channels. Each first channel may be electrically connected to a subset of optical sensors in a corresponding row of the optical sensor array, where there may be at least one optical sensor between connections. Each second channel may be electrically connected to a subset of optical sensors in a corresponding column of the optical sensor array, where there may be at least one optical sensor between connections.
Patent WO-2022051613-A1 (WO)
Title: Production of hydroxylated polyunsaturated fatty acids
Inventor: SCHÜRMANN MARTIN
IPC: C07K14/795
Filed: 2021-09-03
Abstract: A method for producing and purifying hydroxylated polyunsaturated fatty acid (PUFA) derivatives is provided. The method includes reacting a PUFA, preferably eicosapentaenoic acid (EPA) and an enzyme, preferably a P450 enzyme, followed by purification via filtration and/orextraction and/or chromatography. Use of the resulting hydroxylated PUFA derivative, preferably 18-hydroxyeicosapentaenoic acid (18-HEPE) in medicines or food applications, preferably in infant food and/or formula is also provided.
Patent WO-2022055938-A1 (WO)
Title: Systems and methods for microdisk and multiplet laser particles
Inventor: YUN SEOK-HYUN
IPC: G01J3/10
Filed: 2021-09-08
Abstract: A first layer, a first spacer layer, and a second layer of a semiconductor wafer can be etched to produce a plurality of columnar structures extending from the substrate layer and including a first optical cavity situated about the first gain medium, a second optical cavity situated about the second gain medium, and a first spacer region contacting the first gain medium and the second gain medium. Also, a photonic microparticle formed from a layered semiconductor wafer and of a columnar structure having a first optical cavity situated about a first gain medium, a second optical cavity situated about a second gain medium, and a first spacer region contacting the first gain medium and the second gain medium. The first optical cavity and the second optical cavity in the photonic microparticle are each capable of generating laser light with a distinct spectral peak when energetically excited.
Patent WO-2022061057-A1 (WO)
Title: Combining unsupervised and semi-supervised deep clustering approaches for mining intentions from texts
Inventor: BEAVER IAN
IPC: G06F40/00
Filed: 2021-09-17
Abstract: An analysis platform combines unsupervised and semi-supervised approaches to quickly surface and organize relevant user intentions from conversational text (e.g., from natural language inputs). An unsupervised and semi-supervised pipeline is provided that integrates the fine-tuning of high performing language models via a language models fine-tuning module, a distributed KNN-graph building method via a KNN-graph building module, and community detection techniques for mining the intentions and topics from texts via an intention mining module.
Patent WO-2022098526-A1 (WO)
Inventor: CRISP GABRIEL
IPC: G01G5/00
Filed: 2021-10-25
Abstract: La présente invention concerne un tapis d'entretien portable en une seule pièce doté d'un support de manche. Le tapis d'entretien a un coussin de support de manche doté d'un renfoncement situé au centre sur le côté supérieur qui est conçu pour recevoir le manche d'un instrument à cordes. Le support de manche est fixé au niveau de l'extrémité proximale du tapis au côté inférieur dudit support de manche. Des fermetures sont fixées à l'extrémité distale du tapis. Le tapis est conçu pour rouler autour dudit support de manche et être fixé de manière amovible par la fermeture.
Patent WO-2022115550-A1 (WO)
Inventor: BURNS JAMES
IPC: D06N7/02
Filed: 2021-11-24
Abstract: La présente invention concerne un composite fabriqué à partir d'un tissé, d'un non-tissé ou d'un tissu de face tricoté et d'un non-tissé. Le tissé, le non-tissé ou le tissu de face tricoté est aiguilleté de sorte que des fibres fassent saillie dans le non-tissé. Le tissé, le non-tissé ou le tissu de face tricoté comprend un premier polymère ayant un premier point de fusion et un deuxième polymère ayant un deuxième point de fusion qui est supérieur au premier point de fusion. Le matériau de support non tissé comprend un troisième polymère ayant un troisième point de fusion et un quatrième polymère ayant un quatrième point de fusion qui est supérieur au troisième point de fusion. Le tissé, le non-tissé ou le tissu de face tricoté est en outre collé au matériau de support non tissé en appliquant de la chaleur pour faire fondre au moins en partie ou ramollir le premier polymère et le troisième polymère de sorte qu'ils se collent ensemble.
Patent WO-2022164525-A1 (WO)
Title: Rf quadrupole particle accelerator
Inventor: SINCLAIR FRANK
IPC: H01J37/317
Filed: 2021-12-15
Abstract: An apparatus may include a drift tube assembly, the drift tube assembly defining a triple gap configuration, and arranged to accelerate and transmit an ion beam along abeam path. The apparatus may include a resonator, to output an RF signal to the drift tube assembly, and an RF quadrupole triplet, connected to the drift tube assembly, and arranged circumferentially around the beam path.
Patent WO-2022133163-A1 (WO)
Title: Système de corrosion multicouche
Inventor: BOKISA GEORGE
IPC: F16L57/00
Filed: 2021-12-17
Abstract: L'invention concerne un article comprenant un substrat ayant un revêtement multicouche sur au moins une partie de sa surface. Le revêtement multicouche comprend au moins une couche de nickel autocatalytique recouvrant la partie de la surface, au moins une couche de nickel électrolytique recouvrant la couche de nickel autocatalytique et au moins une couche d'étain-nickel électrolytique recouvrant la couche de nickel électrolytique.
Patent WO-2022140183-A1 (WO)
Inventor: SMITH JASON ALAN
IPC: C08G63/80
Filed: 2021-12-17
Abstract: La présente invention concerne une résine de polyester pour des bouteilles moulées par extrusion-soufflage comprenant un glycol aliphatique ramifié et un comonomère de ramification.
Patent WO-2022146918-A1 (WO)
Title: Systèmes pour une localisation dynamique basée sur une image
Inventor: ADEBAR TROY
IPC: A61B90/00
Filed: 2021-12-27
Abstract: Des dispositifs, des systèmes, des procédés et des produits programmes d'ordinateur de mise en œuvre d'actes médicaux sont divulgués dans la présente invention. Dans certains modes de réalisation, un système de mise en œuvre d'un acte médical comprend un instrument médical conçu pour être inséré à l'intérieur de la région anatomique, l'instrument médical comprenant un dispositif de capture d'image. Le système peut être conçu pour obtenir, à partir du dispositif de capture d'image, des données d'image d'un point de repère anatomique à l'intérieur de la région anatomique. Le système peut identifier, sur la base des données d'image, une association entre le point de repère anatomique et un point de repère de modèle correspondant dans un modèle de la région anatomique. Le système peut déterminer un état de localisation de l'instrument médical sur la base de l'association identifiée, l'état de localisation comprenant un emplacement estimé et un paramètre d'incertitude associé à l'emplacement estimé. Le système peut mettre à jour de manière dynamique l'état de localisation lorsque l'instrument médical navigue à l'intérieur de la région anatomique.
Patent WO-2021163716-A1 (WO)
Title: Physical downlink control channel candidate hopping
Inventor: SAKHNINI IYAB ISSAM
IPC: H04L5/00
Filed: 2021-01-22
Abstract: Methods and apparatuses described herein provide a physical downlink control channel (PDCCH) candidate hopping function that reduces collisions between PDCCH candidates, particularly between PDCCH candidates associated with reduced capability user equipment (UE). For example, the hopping function may be implemented as part of a PDCCH candidate to control channel element (CCE) function or may be applied separately from the PDCCH candidate to CCE function. The hopping function may reduce persistent collisions between PDCCH candidates by correlating the mapping behavior with a value that changes over time. Some techniques and apparatuses described herein provide signaling for configuration and activation/deactivation/modification of the hopping pattern. Thus, collisions between PDCCH candidates are reduced, thereby conserving computing resources and wireless communication resources. Furthermore, the reduction of collisions may improve performance of UEs with reduced PDCCH capabilities, such as reduced-capability UEs. Numerous other aspects are provided.
Patent WO-2022177651-A1 (WO)
Inventor: HORN IDAN MICHAEL
IPC: H04L25/02
Filed: 2022-01-03
Abstract: This disclosure provides systems, methods and apparatus, including computer programs encoded on computer storage media, for setting a resolution for an analog-to-digital converter (ADC) of a user equipment (UE) based on a modulated reference signal received from a base station (BS) during a first (for example, initial) symbol period of a slot. In one aspect, the first symbol period of the slot and a cyclic prefix (CP) of the first symbol period may be relatively longer in time than other symbol periods and other CPs of the slot and, in some implementations, the BS may transmit a configuration to the UE allocating a portion of the first symbol period for the transmission of the modulated reference signal. The UE may demodulate the modulated reference signal, calibrate an automatic gain control (AGC) of the UE, and set the resolution of the ADC of the UE based on the modulated reference signal.
Patent WO-2022150584-A1 (WO)
Title: Non-covalent inhibitors of the main protease of sars-cov-2 and methods of use
Inventor: JORGENSEN WILLIAM L
IPC: A61K39/39
Filed: 2022-01-07
Abstract: Provided herein are compounds of formula (I) or (I-A), which act as non-covalent inhibitors of SARS-CoV2 main protease (M pro ). The compounds of formula (I) or (I-A) are useful in treating COVID-19 infections, as well as reducing or ameliorating symptoms associated with COVID-19 infection.
Patent WO-2022150763-A1 (WO)
Inventor: Sweeney Elizabeth
IPC: A61K35/17
Filed: 2022-01-11
Abstract: The present disclosure generally relates target cancer cell specific immunotherapy compositions, methods of making and use thereof. Also provided in the disclosure are methods of treating a cancer in a subject in need thereof.
Patent WO-2022164869-A1 (WO)
Title: Clad wire feedstock for directed energy deposition additive manufacturing
Inventor: SWEENEY CHARLES
IPC: B22F5/12
Filed: 2022-01-26
Abstract: A clad wire feedstock for a directed energy deposition (DED) process is disclosed and includes a core material defining an outer surface and one or more clad metal layers that surround the outer surface of the core material.
Patent WO-2022165155-A1 (WO)
Title: Régulation de l'écoulement de fluide à travers un élément tubulaire de puits de forage
Inventor: SAYEDAKRAM NAWAF I
IPC: E21B43/12
Filed: 2022-01-28
Abstract: La présente invention concerne un système de commande d'écoulement de puits de forage qui comprend un élément tubulaire de production configuré pour s'étendre dans un puits de forage formé à partir d'une surface terrestre et dans une formation souterraine ; une pluralité de vannes de commande d'entrée autonomes (AICV) positionnées sur l'élément tubulaire de production, chacune de la pluralité d'AICV pouvant être commandée sur la base, au moins en partie, d'au moins l'une d'une densité ou d'une viscosité d'un fluide de formation ; et une pluralité de manchons coulissants montés dans l'élément tubulaire de production, chacun de la pluralité de manchons coulissants étant monté à proximité d'un ensemble d'AICV de la pluralité d'AICV, chacun de la pluralité de manchons coulissants pouvant être commandé sur la base d'une pression de soutirage de puits de forage pour coupler ou découpler fluidiquement un volume interne de l'élément tubulaire de production avec la formation souterraine par l'intermédiaire de l'ensemble particulier d'AICV.
Patent WO-2022187236-A1 (WO)
Inventor: ZHANG HONGJIAN
IPC: C07D471/14
Filed: 2022-03-01
Abstract: L'invention concerne de nouveaux composés hétérotricycliques et des analogues, leur fabrication, des compositions pharmaceutiques les comprenant, ainsi que leur utilisation en tant que médicaments pour le traitement d'une maladie associée à des protéines mammifères de la famille RAS (virus du sarcome murin).
Patent WO-2022197755-A1 (WO)
Title: Imidazopyridinyl inhibitors of plasma kallikrein
Inventor: PAPAIOANNOU NIKOLAOS
IPC: A61K31/437
Filed: 2022-03-16
Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.
Patent WO-2022212584-A1 (WO)
Inventor: GALLAGHER LARRY A
IPC: C12N15/11
Filed: 2022-03-30
Abstract: La divulgation concerne des méthodes et des kits, des réactifs et des systèmes associés pour désaminer de manière sélective des résidus cytosine non méthylés dans des molécules d'acide nucléique. Selon certains modes de réalisation, les méthodes et les kits, réactifs et systèmes associés sont utilisés pour des méthodes de détection et/ou de cartographie de résidus cytosine méthylés dans des acides nucléiques. L'acide nucléique peut être un ARN ou un ADN. Selon certains modes de réalisation, la divulgation comprend la mise en contact de l'acide polynucléique avec une cytosine désaminase bactérienne, par exemple DddA ou SsdA, ou des fragments fonctionnels ou des dérivés de ceux-ci. Les DddA et SsdA représentatifs présentent des séquences énoncées respectivement dans SEQ ID NOS : 1 et 2. Les cytosines désaminases bactériennes de la divulgation sont sensibles à la méthylation et, par conséquent, désaminent uniquement les cytosines non méthylées pour fournir une conversion de cytosine en uracile. La conversion peut être détectée sous la forme de transitions C•G-vers-T•A dans une analyse de séquençage ultérieure.
Patent WO-2022216741-A1 (WO)
Title: Electrochemical materials production and processing
Inventor: BENCK JESSE D
IPC: C25B15/08
Filed: 2022-04-05
Abstract: Various embodiments include a system or platform that uses electrochemistry to upcycle waste products and low-value minerals into valuable, carbon dioxide (CO 2 )-neutral materials. Various embodiments may include systems and/or methods for processing material inputs using an electrochemical reactor. Various embodiments may include systems, methods, and/or devices for capturing and sequestering carbon dioxide (CO 2 ) while producing valuable co-products.
Patent WO-2022226152-A1 (WO)
Title: Survivability method for lisp based connectivity
Inventor: JANARDANAN RAJA
IPC: H04L45/42
Filed: 2022-04-21
Abstract: The present disclosure provides systems, methods and computer-readable media for maintaining network connectivity, in a LISP based network, when one or more network edge nodes lose connectivity to a LISP control plane of the network, using multicast messaging. In one example, a method includes receiving a connection request from a first endpoint to a second endpoint communicatively coupled to a second edge node; determining, by the first edge node, that a connection session to a control plane for locating the second endpoint has failed; querying one or more available edge nodes for locating the second endpoint using a multicast message; locating the second endpoint based on at least one query response received from the one or more available edge nodes, at least one query response including an identifier of the second endpoint; and establishing the connection request between the first endpoint and the second endpoint upon locating the second endpoint.
Patent WO-2022226311-A1 (WO)
Title: Nutritional compositions comprising human milk oligosaccharides and a designed lipid component for improving lung function
Inventor: BUCK RACHAEL
IPC: A23L33/00
Filed: 2022-04-22
Abstract: Disclosed are methods of and nutritional compositions for treating or improving at least one marker of lung health in an individual. The nutritional compositions include a combination of a human milk oligosaccharide component and a designed lipid component.
Patent WO-2022240602-A1 (WO)
Inventor: SLAVIN ILYA
IPC: H04L67/1031
Filed: 2022-05-02
Abstract: A method and a system for hosting a market data distribution platform that is widely used by many financial organizations, such as Thomson Reuters Enterprise Platform (TREP), in a public cloud computing environment is provided. The method includes facilitating a communication between the market data distribution platform and at least one server that operates in the public cloud; monitoring an amount of data being distributed on the platform and a number of clients that are accessing the platform; determining a minimum number of cloud servers required for servicing the clients; accessing at least the determined minimum number of servers; and facilitating communications between the servers and the platform. The number of servers and/or load amounts being handled by each server may be adjusted based on varying amounts of data and/or varying numbers of clients.