baber/WOPTO huggingface dataset:
Patent NZ-596861-A (NZ)
Title: Pyrrolidine-substituted flavones as radio-sensitizers for use in the treatment of cancer
Inventor: RATHOS MAGGIE JOYCE
IPC: A61K31/00
Filed: 2010-05-03
Abstract: The disclosure relates to a combination for the treatment of cancer wherein the combination exhibits a synergistic effect. The combination comprises radiation and at least one cyclin dependent kinase (CDK) inhibitor selected from the compounds of formula (I) or a pharmaceutically acceptable salt or a solvate thereof. The present disclosure also relates to the use of said CDK inhibitor for the preparation of a medicament that enhances the efficacy of radiotherapy for the treatment of cancer selected from a group consisting of head and neck cancer, cervical cancer, breast cancer, small cell lung cancer, non-small cell lung cancer, lung adenocarcinoma, ovarian cancer, pancreatic cancer, gastric cancer, colorectal cancer, hepatocellular carcinoma, multiple myeloma, mantle cell lymphoma and malignant melanoma.
Patent NZ-599167-A (NZ)
Title: Dietary fiber composition comprising glucomannan, xanthan gum, alginate and lipid
Inventor: GAHLER ROLAND J
IPC: A23L29/244
Filed: 2008-07-29
Abstract: ABSTRACT - 599167 The disclosure relates to a method for reducing the glycemic index of a food product, the method comprising adding to the food product prior to consumption a dietary fiber composition in an amount of about 2.5 g to about 7.5 g of the dietary fiber composition per 50 g available carbohydrate of the food product effective to reduce the glycemic index of the food product by at least 5 glycemic index units, wherein the dietary fiber composition comprises from about 48% to about 90% (w/w) glucomannan, from about 5% to about 20% (w/w) xanthan gum, and from about 5% to about 30% (w/w) alginate.
Patent NZ-601088-A (NZ)
Title: Alpha 4 beta 2 neuronal nicotinic acetylcholine receptor ligands
Inventor: AHMAD ISHTIYAQUE
IPC: A61K31/403
Filed: 2010-05-03
Abstract: 601088 Disclosed herein is a compound of general formula (I), wherein the variables are defined in the specification; processes for the preparation thereof; and the use thereof in the treatment of a disease related to the ?4?2 nicotinic receptor, such as anxiety, Alzheimer's disease, depression, convulsive disorders, cognitive memory disorders, ADHD (Attention Deficient Disorder/Hyperactivity Syndrome), pain, psychosis, psychotic depression, Parkinson's disease, schizophrenia, sleep disorders, withdrawal from drug abuse syndrome, mild cognitive impairment and obesity. Specific embodiments of the compound include: N-[2-(5-bromopyridin-3-yl)-2-azabicyclo[3.1.0]hex-3-y1methyl]dimethylamine hydrochloride, [2-(5-bromopyridin-3-yl)-2-azabicyclo-[3.1.0]-hex-3-yl] methylamine, furan-2-yl-(3-methylaminomethyl-2-azabicyclo[3.1.0]hex-2-yl) methanone tartarate, and N-(2-(3-methylpyridin-5-yl)-2-azabicyclo[3.1.0]hex-3-ylmethyl)methylamine bistartarate. Where the process comprises: coupling a 2-azabicyclo[3.1.0]hexane of formula (12) with an acid halide of formula (13) to form a compound of formula (14); converting the hydroxyl group of formula (14) to a mesylate group to form a compound of formula (15); and reacting the compound of formula (15) with alkyl amines to form a compound of formula (I); or reacting a compound of formula (15) with an azide to form a compound of formula (16) followed by reduction of the azide group to form a compound of formula (I). Wherein the process comprises: coupling a compound of formula (17) with an acid halide of formula (13) to form a compound of formula (19); and deprotecting the compound of formula (19) to form a compound of formula (I).
Patent NZ-602626-A (NZ)
Title: Generation of oxygen in hospitals
Inventor: GRAHL MATTHIAS
IPC: B01D53/047
Filed: 2011-03-01
Abstract: 602626 Disclosed are an arrangement for generating oxygen in a medical facility and methods for operating and installing an arrangement in a medical facility. Smaller medical facilities require higher investment costs to install and utilise such arrangements for generating oxygen. Furthermore, the arrangements have poor consumption figures. The arrangement comprises at least one unit for generating medical air (V, R); a vacuum system (VS) and a pressure swing adsorption (PSA) unit (A). The vacuum system (VS) and PSA unit (A) are interconnected and serve to generate an oxygen product stream (5). The connection between the vacuum system (VS) and PSA unit (A) allows the adsorbers of the PSA unit (A) to be regenerated by the vacuum system (VS). The unit for generating medical air (V, R) is connected to the PSA unit (A) in such a way that at least a subsidiary stream (2) of the generated medical air is delivered as feed gas to the PSA unit (A).
Patent NZ-603206-A (NZ)
Title: Exercise apparatus
Inventor: LENZ STEVE
IPC: A63B21/008
Filed: 2011-03-25
Abstract: An exercise apparatus 10 comprising a stationary cushion 18 defining a running surface on which a user may be supported in a standing position, where the cushion 18 is configured to receive footfalls of the user from a running impact, a frame 14 attached to the cushion 18, and a tensionable resistance member 106 attached to the frame 14 and engageable by the user. The tension within the resistance member 106 is variable for a given position of the user.
Patent NZ-609221-A (NZ)
Title: Benzoxazole kinase inhibitors and methods of use
Inventor: CHAN KATRINA
IPC: C07D413/14
Filed: 2009-11-02
Abstract: Disclosed herein is a 4-Amino-7-isopropyl-pyrazolo[3,4-d]pyrimidine-benzoxazole derivative represented by structural formula shown herein, a process for its preparation, compositions comprising said compound and uses thereof. Said compound is useful as a kinase inhibitor, in particular mTor, Akt and phosphoinositide 3-kinase (PI3K), as such is useful in ameliorating a disorder selected from the group consisting of cancer, kidney diseases, bone disorder, inflammatory disease, immune disease, nervous system disease, metabolic disease, respiratory disease, and cardiac disease.
Patent NZ-612115-A (NZ)
Title: System and apparatus for connecting a gas source to a thermal oxidiser
Inventor: CORK DAVID JOHN
IPC: E21F1/04
Filed: 2011-11-24
Abstract: 612115 A system for the safe connection of thermal oxidisers (10), gas engine or boilers etc. to a working coal mine (2) is disclosed. Methane may be released from underground coal mines as part of the ventilation air and is known as Ventilation Air Methane (VAM). As methane is a powerful greenhouse gas thermal oxidiser processes have been proposed to burn out VAM as a greenhouse abatement technology. However, these thermal oxidisers, and other VAM combustion systems, represent a possible ignition source. There needs to be a system that can safely, and consistently, isolate the thermal oxidisers from the coal mine within seconds. A duct (5) that has a sufficiently sized cross-sectional diameter to reduce the velocity of the gas to below 7 m/s is used to connect the mine ventilation system to the thermal oxidiser. This provides slower gas velocity and therefore ensures more time before a slug of methane reaches the thermal oxidiser, increasing the time between detection of a methane event and successful operation of mitigation mechanisms. These mechanisms are disclosed as Independent Protection Layers (IPL) and are designed to operate independently of each other. These IPL’s could be vents (4), barriers (6), dilution doors (7), frangible vents (8) or isolation valve (9). A number of possible events that could be used to trigger the protection system are disclosed.
Patent NZ-615366-A (NZ)
Title: Partially crystallized polyester containers
Inventor: LONGO EUGENIO
IPC: B65D77/20
Filed: 2012-03-12
Abstract: A clear polyester container comprising a base and upwardly extending side walls terminating in a continuous flange projecting from the side walls is described. The container comprises an inner layer (1.1) in amorphous phase and an outer layer comprising a nucleating agent in the polymer composition in order to be crystallized in at least one portion (1.2) of the flange. This enables a shrinkable lid film to be heat sealed to the flange with good sealability and the container to be able to withstand the shrink of a lid without distortion while maintaining a clear bowl portion (1.3).
Patent NZ-615895-A (NZ)
Title: Pole shoe of a generator, preferably a generator of a wind turbine generator system
Inventor: HILDEBRAND ARNO
IPC: H02K5/04
Filed: 2012-03-23
Abstract: A pole shoe, for a generator comprising a pole assembly 4 which is of a laminated configuration, at least one winding 6 arranged around the pole assembly 4, and at least one end portion 1 provided at least one end of the pole assembly 4 in a longitudinal direction (A) thereof between the pole assembly 4 and the winding 6. The end portion 1 has rounded edges to provide an edge-free transition between the end portion and the pole assembly 4 for the winding 6. An insulating means is arranged between the pole assembly and the winding. The insulating means produces an adhesive connection between the pole assembly and the winding.
Patent NZ-617010-A (NZ)
Title: Method and apparatus for growing plants along an undulating path
Inventor: BENNE JACOB
IPC: B65G17/30
Filed: 2012-05-02
Abstract: Plants are grown in a growing machine (10) by advancing a plurality of plant cradles (14) on an endless conveyor along a growing path (P), at least a portion of the path being an undulating path having alternating upward and downward portions and a return portion for looping back to the undulating portion. Using a pair of parallel endless conveyors (12, 12), the cradles are removably supported between the conveyors. The cradles are supplied with growth-sustaining liquid and growth-promoting light. The cradles are advanced along the path until the one or more plants have reached a target growth after which they can be harvested or transferred to one or more subsequent machines until mature for harvest. As the cradles move upwards they are tilted to be higher at one end than the other and as they move downwards they are tilted in the opposite angle so that the nutrient in the cradle washes through the roots of the plants.
Patent NZ-618515-A (NZ)
Title: Process for producing liquid hydrocarbon
Inventor: IVERSEN STEEN BRUMMERSTEDT
IPC: C10G1/10
Filed: 2012-06-11
Abstract: Disclosed herein is a continuous process for converting carbonaceous material contained in one or more feedstocks into a liquid hydrocarbon product, said feedstocks including the carbonaceous material being in a feed mixture including one or more fluids, said fluids including water and further liquid organic compounds including liquid hydrocarbons at least partly produced by the process in a concentration of at least 10 % by weight and at least 0.5 wt % of a homogeneous catalyst in the form of a compound of potassium and/or sodium, the process comprising: converting at least part of the carbonaceous material by pressurising the feed mixture to a pressure in the range 250-400 bar; heating the feed mixture to a temperature in the range 385-430 °C, controlling the pH during said conversion to above 7, where the pH is measured during and/or after the conversion and when the pH is outside the preferred range, the composition of the feed mixture is altered to correct the pH in the conversion, and maintaining said pressurized and heated feed mixture in the desired pressure and temperature ranges in a reaction zone for a predefined time; thereby causing the carbonaceous material to be converted to a liquid hydrocarbon product; and cooling the feed mixture to a temperature in the range 25-200 °C, and expanding the feed mixture to a pressure in the range of 1-70 bar, and separating from the converted feed mixture a fraction comprising liquid hydrocarbon product.
Patent NZ-620653-A (NZ)
Title: Oxy-cyclohexyl-4h,6h-5-oxa-2,3,10b-triaza-benzo[e]azulenes as v1a antagonists
Inventor: DOLENTE COSIMO
IPC: C07D498/04
Filed: 2012-09-24
Abstract: The present disclosure provides 4H,6H-5-oxa-2,3,10b-triaza-benzo[e]azulenes (I), which act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful as therapeutics acting peripherally and centrally in the conditions of dysmenorrhea, male or female sexual dysfunction, hypertension, chronic heart failure, inappropriate secretion of vasopressin, liver cirrhosis, nephrotic syndrome, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, and aggressive behaviour.
Patent NZ-628067-A (NZ)
Title: Food processing tool
Inventor: PENDLETON OLIVER
IPC: A47J43/10
Filed: 2012-12-18
Abstract: Food processor attachment (10). The tool (10) comprises first and second curved blades (20, 30) which depend from a casing part (40) that is rotated within a processing bowl (60) by means of a geared arrangement that picks up rotary drive from a drive shaft (43) coupled to a driven outlet on the base of the food processor. The blades (20, 30) are disposed at different distances from the axis about which the casing rotates, so that the outer blade (20) passes closer to the wall of the bowl (60) than does the inner blade (30), and the food-contacting surfaces of the blades are each formed to gently lift and turn ingredients, such that the outer blade (20) turns ingredients in towards the axis and the inner (30) blade turns ingredients outwardly therefrom. The blades (20, 30) may be mounted to the casing part (40) for simple bodily rotation therewith. Alternatively, one or both of the blades (20, 30) may be capable of rotation relative to the casing part (40). The blades (20, 30) can be made removable from the casing part (40) to facilitate cleaning.
Patent NZ-629136-A (NZ)
Title: Phytocannabinoids in the treatment of cancer
Inventor: SUTTON ALAN
IPC: A61P35/00
Filed: 2011-03-11
Abstract: This disclosure relates to a cannabis plant extract comprising a phytocannabinoid containing component and a non-phytocannabinoid containing component, wherein the phytocannabinoid containing component comprises 64-78% (w/w) of the cannabis plant extract and the nonphytocannabinoid containing component comprises a monoterpene fraction in which a principal monoterpene sub-fraction is selected from myrcenes or pinenes and a principal sesquiterpene sub-fraction is selected from caryophyllenes or humulenes, and wherein a principal phytocannabinoid is cannabidivarin (CBDV).
Patent NZ-629728-A (NZ)
Title: Morpholinoalkyl fumarate compounds, pharmaceutical compositions, and methods of use
Inventor: CUNDY KENNETH C
IPC: C07D265/30
Filed: 2013-02-07
Abstract: Morpholinoalkyl fumarates, pharmaceutical compositions comprising the morpholinoalkyl fumarates, and methods of using morpholinoalkyl fumarates and pharmaceutical compositions for treating neurodegenerative, inflammatory, and autoimmune disorders including multiple sclerosis, psoriasis, irritable bowel disorder, ulcerative colitis, arthritis, chronic obstructive pulmonary disease, asthma, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis are disclosed. An example of the compound is methyl (S-morpholinopentyl) fumarate HCl salt.
Patent NZ-715595-A (NZ)
Title: Treatment of disease with poly-n-acetyglucosamine nanofibers
Inventor: FINKIELSZTEIN SERGIO
IPC: A61P29/00
Filed: 2012-04-16
Abstract: Use of a composition comprising shortened fibers of poly-β-1→4-N-acetylglucosamine (“sNAG nanofibers”) for topical administration for treating inflammatory bowel disease in a human subject having inflammatory bowel disease, such as ulcerative colitis or Crohn’s disease, wherein the sNAG nanofibers comprise 70%, or more than 70%, of N-acetylglucosamine monosaccharides, and wherein (i) more than 50% of the sNAG nanofibers are between 1 to 15 µm in length, or (ii) the sNAG nanofibers are less than about 15 µm in length. Preferably the sNAG nanofibers are of microalgal origin,
Patent NZ-724215-A (NZ)
Title: Method for producing substituted 5-fluoro-1h-pyrazolopyridines
Inventor: BIERER DONALD
IPC: C07D471/04
Filed: 2012-11-21
Abstract: The disclosure relates to a method for producing an aldehyde of the formula (III) which are further used in the preparation of substituted 5-fluoro-1H-pyrazolopyridines. The substituted 5-fluoro-1H-pyrazolopyridines are suitable as an intermediate for producing medicaments, in particular medicaments for the treatment and/or prophylaxis of cardiovascular disorders.
Patent NZ-724347-A (NZ)
Title: Gas delivery device and system
Inventor: BATHE DUNCAN P
IPC: G05D7/06
Filed: 2011-01-06
Abstract: A gas delivery system including a gas delivery device (100), a control module (200) and a gas delivery mechanism is disclosed. An exemplary gas delivery device includes a valve (107) assembly with a valve and circuit including a memory, a processor and a transceiver in communication with the memory. The memory may include gas data such as gas identification, gas expiration and gas concentration. The transceiver on the circuit of the valve assembly may send wireless optical line - of - sight signals (300) to communicate the gas data to the control module. Exemplary gas delivery mechanisms include a ventilator (400) and a breathing circuit (410). Methods of administering gas are also described. The gas data is compared to patient data to verify the correct therapy is being administered. An alarm may indicate when the verification process discovers a discrepancy. A control module is configured to evaluate the gas data to determine that the gas source meets at least one criteria where the gas data includes at least one of gas identification, gas expiration and gas concentration.
Patent NZ-725474-A (NZ)
Title: Shock-absorbing device for a humanoid robot
Inventor: CLERC VINCENT
IPC: F16F1/377
Filed: 2015-05-07
Abstract: The present invention relates generally to a shock-absorbing device for securing and protecting electronics against shocks. The present invention protects electronics embedded in a humanoid robot against fall of said robot, as such a fall is particularly detrimental to the robot. An aspect of the present invention provides a shock-absorbing device for a mobile robot comprising: a rigid structure linkable to the mobile robot; a deformable outer shell; a shock-absorber; and an electronic module fixed to the rigid structure, the shock-absorber comprising a flexible cellular structure, wherein the flexible cellular structure comprises a set of cells emerging in a main direction, wherein the set of cells is secured to the rigid structure at a first end in the main direction, and wherein the set of cells is linked to the deformable outer shell at a second end opposite the first end in the main direction, and wherein the flexible cellular structure is configured to define a chimney emerging at both ends in the main direction, the chimney being configured to discharge heat emitted by the electronic module out of the robot.
Patent NZ-726785-A (NZ)
Title: Injection zone markers for biomedical implants
Inventor: HRISTOV KRASIMIRA
IPC: A61F2/12
Filed: 2015-04-22
Abstract: A mammary implant (10) and method of making are provided herein. The implant includes an outer shell (12) configured to retain fluid therein, an injection element (14) coupled to the outer shell and adapted to receive therethrough an injection device for injecting fluid into the outer shell, and an injection marker zone (16) made of a material having ultrasonically detectable markers (100) incorporated therein. The markers are a plurality of microcavities that are located relative to the injection element so that, when ultrasonically detected, such detection indicates a location of the injection element.
Patent NZ-737669-A (NZ)
Title: Inflammation-suppressing composition including peptide
Inventor: ANO YASUHISA
IPC: A61P29/00
Filed: 2016-05-26
Abstract: Provided is a composition that can be used to suppress microglia inflammation and is based on the discovery of oligopeptides that have a superior anti-inflammatory effect on microglia. The inflammation-suppressing action of dipeptides was comprehensively analyzed using the production of inflammatory cytokines in microglia as an indicator. The results clearly showed that oligopeptides containing an LH, DV, or MH sequence have a superior inflammation-suppressing effect. With compositions that include these oligopeptides, the present invention provides a composition that has the effect of suppressing excessive inflammatory action in microglia.
Patent NZ-739788-A (NZ)
Title: Phthalocyanine dye conjugates and their storage
Inventor: MAKINGS LEWIS
IPC: A61P35/00
Filed: 2016-08-18
Abstract: Provided are methods for manufacturing a conjugate containing a phthalocyanine dye, including methods that include one or more steps of preparing or producing the conjugate, formulating the conjugate and packaging the conjugate. In some aspects, the manufacturing methods result in the generation of a stable conjugate. Also provided are stable phthalocyanine dye conjugates, compositions and articles of manufacture containing the stable conjugates, and methods for their administration to subjects for photoimmunotherapy. In some embodiments, the phthalocyanine dye conjugates are conjugated to a targeting molecule, such as an antibody, that targets the conjugate to a cell or pathogen, such as by binding to a cell surface protein.
Patent NZ-742080-A (NZ)
Title: Reticle for optical sighting devices
Inventor: HAMILTON DAVID M
IPC: G02B27/32
Filed: 2016-10-27
Abstract: A reticle for an optical sighting device, such as a riflescope, with subtension markings of varying thicknesses and scales along both horizontal and vertical stadia lines, with the coarse subtension markings below the horizontal stadia line, to accommodate both stationary and moving targeting such as dialing for elevation but holding for windage. The optical sighting device includes an objective lens system having a center axis, an eyepiece lens, and an erector lens system forming an optical system having a first focal plane and a second focal plane, the first focal plane proximate the objective lens system, and the second focal plane proximate the eyepiece lens. The reticle includes separate numerical markings along the horizontal stadia line.
Patent NZ-746784-A (NZ)
Title: Glucagon and glp-1 co-agonists for the treatment of obesity
Inventor: BEDNAREK MARIA
IPC: A61P3/04
Filed: 2017-03-10
Abstract: Provided herein are methods of preventing and treating obesity and diabetes in patients comprising administering GLP-1/glucagon agonist peptides. Specifically, comprising the use of a known glucagon/GLP-1 receptor agonist (SEQ ID No. 19) for the treatment of diseases and disorders associated with excess body and/or liver fat, including obesity, diabetes and Non-alcoholic Steatohepatitis (NASH) shown by the reduction of liver fat and/or increase in lipid oxidation.
Patent NZ-751580-A (NZ)
Title: 4-amino-6-(heterocyclic)picolinates and their use as herbicides
Inventor: ECKELBARGER JOSEPH D
IPC: C07D401/04
Filed: 2014-03-12
Abstract: A compound defined by formula I wherein: R1’ is hydrogen, C1-C8 alkyl, or C7-C10 arylalkyl, or an agriculturally acceptable N-oxide or salt thereof is provided. Also provided are herbicidal compositions including these compounds, as well as methods of using thereof as herbicides. The occurance of undesirable vegetation, e.g., weeds, is a constant problem facing farmers in crops, pasture, and other settings. Weeds compete with crops and negatively impact crop yield. The use of chemical herbicides is an important tool in controlling undesirable vegetation.