baber/WOPTO huggingface dataset:
Patent JP-2024005561-A (JP)
Title: 車両用灯火システム
IPC: B60Q1/24
Filed: 2022-06-30
Abstract: 【課題】 暗所において自車両の周辺領域に存在する物標を鮮明に撮影可能とする車両用灯火システムを提供する。【解決手段】 車両用灯火システム１は、自車両の周囲の物標ＯＢに関する物標情報を出力する情報出力装置と、自車両に設けられた複数の灯火装置の点灯状態をそれぞれ制御する制御装置と、を備える。制御装置は、前記情報出力装置が出力する物標情報に基づいて、自車両の周囲の照度Ｂが閾値Ｂｔｈ以下であって、且つ自車両が自車両の周囲の物標ＯＢと衝突する可能性があると判断した場合に、物標ＯＢが存在する方向の照度が増大するように各灯火装置の点灯状態を制御する灯火制御を実行する。【選択図】 図４
Patent JP-2024008094-A (JP)
Title: 検査装置
IPC: G01B7/00
Filed: 2022-07-07
Abstract: 【課題】静電容量式変位計の測定に影響を及ぼさずに、信頼性が高い計測結果だけを記録する検査装置を提供する。【解決手段】検査装置は、導電材料製の計測対象との距離を計測する静電容量式変位計と、静電容量式変位計のセンサグランドが電気的に接続された接地部と、計測対象が取り付けられた導電材料製の板である支持部を押圧して支持部を固定し、接地部に接触する２つの押圧ピンと、静電容量式変位計が距離を計測していない時間に、支持部を含む部分の２つの地点の間の抵抗を測定する抵抗測定計と、抵抗が閾値より低い場合に、抵抗の測定前に静電容量式変位計で計測された計測結果を記録する測定制御部とを備える。２つの押圧ピンの少なくとも１つは導電材料製である。【選択図】図１
Patent JP-2022137241-A (JP)
Title: Adeno-associated virus formulations
IPC: A61K47/18
Filed: 2022-07-15
Abstract: PROBLEM TO BE SOLVED: To provide adeno-associated virus liquid and lyophilized pharmaceutical compositions. 
     SOLUTION: In exemplary aspects, the pharmaceutical compositions comprise about 5 mM to about 25 mM of L-histidine, about 0 mM to about 150 mM of sodium chloride, about 0.001% (w/v) to about 0.01% (w/v) of polysorbate 80 (PS80), about 1% to about 10% (w/v) of sucrose, trehalose or a combination thereof, and the AAV. In exemplary aspects, the pharmaceutical compositions further comprise glycine or mannitol. Methods of preparing a pharmaceutical composition comprising the AAV, methods of treating a bleeding disorder in a subject, and methods of storing AAV compositions are also provided. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2022,JPO&INPIT
Patent JP-2023024315-A (JP)
Title: METHOD FOR MANUFACTURING SiC SINGLE CRYSTAL
Inventor: SHINTANI HISAFUMI
IPC: C30B29/36
Filed: 2022-07-22
Abstract: SOLUTION: To provide a method for manufacturing an SiC single crystal by a solution method in which alloy of Si and a metal element M which increases the solubility of C is previously impregnated as melt into an SiC sintered compact having the relative density of 50 to 90%, and then, an SiC crucible made of the SiC sintered compact is allowed to house metal element M which increases the solubility of Si and C, and Si and the metal element M in the SiC crucible are fused to form Si-C solution.EFFECT: Because Si-C solution infiltrates into a sintered compact, SiC being a component of a SiC sintered compact is eluted into Si-C solution by heating even from inside the sintered compact, and Si and C are efficiently supplied to the Si-C solution. As a result, Si and C are supplied from the entire contact part of a SiC crucible with the Si-C solution evenly and appropriately, which makes it possible to stably manufacture a high-quality SiC single crystal at high growth rate and for a long period of time.SELECTED DRAWING: Figure 1
Patent JP-2022140618-A (JP)
Title: Electronic device and manufacturing method for the same
IPC: H01L25/065
Filed: 2022-08-02
Abstract: PROBLEM TO BE SOLVED: To provide an electronic device for excellent signal transmission properties between chips and stable power supply performance to the chips. 
     SOLUTION: An electronic device 1 includes a wiring layer 40, a second chip 20 and a third chip 30 provided on one surface of the wiring layer 40, and a first chip 10 provided on the other surface of the wiring layer 40. The wiring layer 40 includes conductive members 41, 42 that connect between the first chip 10 and the second chip 20, and between the first chip 10 and the third chip 30, respectively, and does not include a conductive member that connects directly between the second chip 20 and the third chip 30. 
     SELECTED DRAWING: Figure 1 
     COPYRIGHT: (C)2022,JPO&INPIT
Patent JP-2022166116-A (JP)
Title: Method and system for generating surface signature
IPC: G06T7/00
Filed: 2022-08-05
Abstract: PROBLEM TO BE SOLVED: To provide a system and a method for taking out a digital signature from a surface arranged in an arbitrary mode for and inclined with respect to an image acquisition plane by using an image of the surface. 
     SOLUTION: There is provided a method for generating a digital signature on an inspection surface being at least one surface of a material element, and the method includes: an acquisition step (E30) for obtaining an offset image of the inspection surface for each inspection surface; an acquisition step (E50) for obtaining an interest area by collating the offset image and an equivalent area with each other by template matching; and an acquisition step (E70) of acquiring an image in which the offset image is aligned with a model image. The alignment is performed by applying first perspective transformation to the offset image, and the first perspective transformation is obtained from at least one interest area and at least one equivalent area. The method further includes a generation step (E90) of generating a digital signature that characterizes a structure of the inspection surface from the aligned image. 
     SELECTED DRAWING: Figure 5 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2022162072-A (JP)
Title: elevator
IPC: B66B1/50
Filed: 2022-08-24
Abstract: PROBLEM TO BE SOLVED: To provide an elevator capable of suppressing an erroneous operation to a car operation part. 
     SOLUTION: An elevator comprises: a car; multiple car operation parts for performing a non-contact operation for operating a car and detect the operation; a processing part for operating the car based on the detected operation by the car operation parts; and an effective operation part for performing the non-contact operation to enable the operation to the car operation part, and detecting the operation. The processing part enables the operations to the multiple car operation parts when the effective operation part detects the operation. 
     SELECTED DRAWING: Figure 3 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023033240-A (JP)
Title: Method for molding composite material
Inventor: CHOU CHIEN-HSU
IPC: C08J5/24
Filed: 2022-08-26
Abstract: To provide a method for molding a composite material.SOLUTION: A method for molding a composite material comprises the steps of: disposing a component to be pressed in a gas-isolation element to place the same between two pressing plates; disposing a plate material based on a location of a prepreg element of the component to be pressed; performing hot pressing; and cooling the same to produce a composite material of the present application. A dimension of the composite material produced can be easily adjusted to meet requirements of various applications.SELECTED DRAWING: Figure 1
Patent JP-2022162136-A (JP)
Title: Mobile air vehicle device
IPC: B64F1/12
Filed: 2022-08-26
Abstract: PROBLEM TO BE SOLVED: To provide a mobile air vehicle device which prevents falling of an air vehicle during transportation to achieve improvement of durability of the air vehicle and secure the operation rate for a long time and is advantageous for performing monitoring work reliably. 
     SOLUTION: An air vehicle takeoff and landing part 44 is provided with a falling prevention part 62 which prevents an air vehicle 38 from falling from the air vehicle takeoff and landing part 44 when the air vehicle takeoff and landing part 44 is transported by an unmanned work machine 12A for transportation in a state where the air vehicle 38 is placed on the air vehicle takeoff and landing part 44. Even if an area where the unmanned work machine 12A for transportation travels is an off-road area and swinging and vibration occurring during traveling act on the air vehicle 38 placed on the air vehicle takeoff and landing part 44, the falling prevention part 62 prevents falling of the air vehicle 38 from the air vehicle takeoff and landing part 44. 
     SELECTED DRAWING: Figure 1 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2022169764-A (JP)
Title: Systems and methods for identifying and tracking physical objects during robotic surgical procedure
IPC: A61B34/20
Filed: 2022-08-31
Abstract: PROBLEM TO BE SOLVED: To provide navigation systems and methods for tracking physical objects near a target site during a surgical procedure. 
     SOLUTION: A navigation system comprises a robotic device and an instrument attached to the robotic device. A vision device is attached to the robotic device or the instrument and generates multiple vision data sets. The vision data sets are captured from multiple perspectives of the physical object. A computing system associates a virtual object with the physical object on the basis of one or more features of the physical object identifiable in the vision data sets. The virtual object at least partially defines a virtual boundary for the instrument. 
     SELECTED DRAWING: Figure 3 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2022183147-A (JP)
Title: optical film
IPC: H05B33/02
Filed: 2022-09-06
Abstract: PROBLEM TO BE SOLVED: To provide an optical film that offers superior capability to prevent light leakage while displaying black. 
     SOLUTION: There is provided an optical film comprising: a first retardation layer; and a second retardation layer which exhibits an optical property represented by an expression (3). The optical film exhibits optical properties represented by expressions (1) and (2). The expressions are as follows: Re(450)/Re(550)≤1.00 ...(1), 1.00≤Re(650)/Re(550) ...(2), nx≒ny<nz ...(3), where Re(450) represents an in-plane retardation value at a wavelength of 450 nm, Re(550) represents an in-plane retardation value at a wavelength of 550 nm, and Re(650) represents an in-plane retardation value at a wavelength of 650 nm, while nx represents a principal refraction index in a direction parallel to a film plane in a refractive index ellipsoid formed by the retardation layers, ny represents a refractive index in a direction parallel to the film plane and perpendicular to the nx direction, and nz represents a refractive index in a direction perpendicular to the film plane. 
     SELECTED DRAWING: Figure 1 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023015071-A (JP)
Title: Scanning probe system for controlling tilt angle of probe chip
IPC: G01Q20/02
Filed: 2022-10-18
Abstract: PROBLEM TO BE SOLVED: To provide a method for scanning features by a probe having a cantilever extended from a cantilever mounting part of a free end and a probe chip carried by the free end of the cantilever. 
     SOLUTION: A direction of a probe is measured relative to a reference surface and a probe direction measurement value is generated. The reference surface demarcates a reference surface axis vertical to the reference surface and a probe chip has a reference tilt angle relative to the reference surface axis. A shape of a cantilever is changed according to a probe direction measurement value such that the probe chip relatively travels to a cantilever mounting part and a reference tilt angle decreases from a first reference tilt angle to a second reference tilt angle. A sample surface is scanned by the probe, a sample surface axis vertical to the sample surface is demarcated, and the probe chip has a scanning tilt angle relative to the sample surface axis. The cantilever mounting part is moved during scanning, and as a result, the probe chip is inserted into features on a sample surface at a scanning tilt angle less than the first reference tilt angle. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023021973-A (JP)
Title: Powder container and system using the same
IPC: B33Y10/00
Filed: 2022-10-20
Abstract: PROBLEM TO BE SOLVED: To appropriately prevent corrosion and oxidation or other deterioration of powder by charging and storing the powder in a container. 
     SOLUTION: A powder container (10) includes a pressure container (12) storing powder (14) and pressure gas (32), a discharge port through which the powder can flow out of the pressure container when in use, and a discharge port valve (24) to selectively open and close the discharge port. The container further includes a data detection and/or recording means structured to monitor and/or record various parameters of the powder and/or the pressure gas (32) and a control unit structured to register and record a sensor measurement value continuously or intermittently. The control unit includes a communication module structured to rely the sensor measurement value to a remote monitoring station or to record a file. 
     SELECTED DRAWING: Figure 1 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2022189913-A (JP)
Title: Carbohydrate-based polymeric materials
IPC: B29D7/01
Filed: 2022-10-21
Abstract: PROBLEM TO BE SOLVED: To provide articles including carbohydrate-based polymeric materials, and methods for forming such articles. 
     SOLUTION: There are described herein articles including carbohydrate-based polymeric materials, and methods for forming such articles. Such articles may exhibit improved sustainability, biodegradability, increased strength, and/or other various beneficial characteristics. The carbohydrate-based polymeric material may be formed from one or more starches, a plasticizer (e.g., glycerin), and water. The carbohydrate-based polymeric material may exhibit very low crystallinity characteristics, so as to be substantially amorphous (e.g., having a crystallinity of no more than 20%, no more than 10%, less than 10%, etc.). The carbohydrate-based polymeric materials may be blended with non-biodegradable plastics to render those plastic materials biodegradable, it may lend increased strength to the film or other article, it may be blended with a sustainable polymeric material (e.g., bioPE or the like) for increased sustainability (e.g., as much as 90% or more), or the like. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023015136-A (JP)
Title: Magnetic distributed mode actuators and distributed mode loudspeakers having the same
IPC: H04R1/02
Filed: 2022-10-26
Abstract: PROBLEM TO BE SOLVED: To provide a distributed mode loudspeaker, a mobile device and a wearable device that realize a stronger output than conventional piezoelectric magnetic DMAs. 
     SOLUTION: In a flat panel 104 extending in a plane, a distributed mode actuator (DMA) 310 includes a rigid, elongate member 330 extended parallel to the plane. The member is mechanically coupled to a face of the flat panel at a point. An end of the member is free to vibrate in a direction perpendicular to the plane. The DMA also includes magnets 324-328 and an electrically conducting coil 322. Either the magnets or the coil is mechanically coupled to the member. When the coil is energized, an interaction between a magnetic field of the magnets and a magnetic field from the coil applies a force sufficient to displace the member in the direction perpendicular to the plane. The DMA further includes an electronic control module electrically coupled to the coil and programmed to energize the coil to vibrate the member to produce an audio response from the flat panel. 
     SELECTED DRAWING: Figure 3 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023015352-A (JP)
Title: Device and method for wound treatment
IPC: A61M27/00
Filed: 2022-11-21
Abstract: PROBLEM TO BE SOLVED: To provide a device for treating wounds with negative pressure and/or therapeutic agent. 
     SOLUTION: A wound treatment device 20 has a chamber 22 defining a treatment space 24 having an inner surface mechanically designed. The inner surface includes a plurality of structures. The plurality of structures are configured to provide pathways for the distribution of negative pressure and to exert mechanical stress on a wound. One or more tubes may be in fluid communication with the treatment space to facilitate application of negative pressure, introduction of the therapeutic agent, and removal of wound material. 
     SELECTED DRAWING: Figure 1 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023014396-A (JP)
Title: Bifidobacteria survival-improving composition
IPC: C12N1/20
Filed: 2022-12-05
Abstract: PROBLEM TO BE SOLVED: To improve the survival of bifidobacteria, particularly the survival during cold storage, without the need for externally adding non-milk components, and without affecting the flavor or physical properties of food. 
     SOLUTION: The problem is solved by a composition for improving the survival of bifidobacteria containing decomposed milk protein. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023103964-A (JP)
Title: Image blur correction apparatus, control method therefor, imaging apparatus, program, and storage medium
Inventor: NARITA MASARU
IPC: H04N23/68
Filed: 2022-12-09
Abstract: To provide an image blur correction apparatus capable of performing object blur correction without impairing quality of an image even when parts of an object to be detected are switched.SOLUTION: Included are: object detection means configured to detect an object for each part from an input image and output a position of the part of the object detected; selection means configured to select a part of the object from the part of one or more objects detected by the object detection means on the basis of a predetermined priority; and object blur correction amount calculation means configured to calculate an object blur correction amount for correcting object blur on the basis of a difference between a position of the part of the object selected by the selection means and a predetermined target position in the image. The object blur correction amount calculation means, when the part of the object selected by the selection means is switched from a first part to a second part, calculates the object blur correction amount on the basis of a difference between the position of the selected part of the object and the target position, a position of the second part in the image, and a position of the second part in the image acquired before the switching.SELECTED DRAWING: Figure 1
Patent JP-2023027241-A (JP)
Title: Method and system for processing a biological sample
IPC: C12N5/076
Filed: 2022-12-09
Abstract: PROBLEM TO BE SOLVED: To provide a method, system and apparatus for processing a biological sample into its constituent components for use in the field of assisted reproductive technologies. 
     SOLUTION: Provided is a method of processing a semen sample comprising the steps of: introducing the semen sample into a first volume disposed adjacent a second volume comprising buffer solution, the first and second volumes being adapted for fluid communication therebetween; and selectively separating the first volume from the second volume with a movable closure member disposed therebetween. The step of separating comprises moving the closure member so that a fluid communication aperture is formed by one or a combination of the closure member or the closure member in combination with the first and second volumes to allow fluid communication between the first volume and the second volume such that motile sperm migrate from the semen sample in the first volume to the buffer solution in the second volume. 
     SELECTED DRAWING: None 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023053950-A (JP)
Title: Ice making machine
IPC: F25D23/06
Filed: 2022-12-19
Abstract: PROBLEM TO BE SOLVED: To provide an ice making machine having an ice maker, and a further streamlined cleaning method of the same. 
     SOLUTION: An ice maker includes an evaporator case 206. The evaporator case 206 includes: a plurality of inside panels which is the plurality of inside panels joined with each other by snap fitting joints, in which each of the snap fitting joints includes a tab and defines a slot, and in which each of a plurality of seams formed between the inside panels defines a foam tight seal and a water tight seal; and a plurality of outside panels which is the plurality of outside panels, in which each of the plurality of outside panels is joined to the mating inside panel out of the plurality of inside panels by slide joints. The evaporator case 206 is integrally heat-insulated by a foam heat insulation material arranged between each of the plurality of outside panels and the corresponding inside panel. 
     SELECTED DRAWING: Figure 5A 
     COPYRIGHT: (C)2023,JPO&INPIT
Patent JP-2023098715-A (JP)
Title: Prediction method, and food and drink composition
Inventor: KAMIIZAWA Ryota
IPC: A23L33/17
Filed: 2022-12-28
Abstract: To provide a prediction method that can predict the effect of lactoferrin ingestion, and a food and drink composition.SOLUTION: A prediction method for an abdominal visceral fat area reduction effect of lactoferrin includes the steps of: determining alleles of a single nucleotide polymorphism involved in an abdominal visceral fat area reduction effect in a DNA-containing sample derived from a subject; and predicting an abdominal visceral fat area reduction effect by the subject ingesting lactoferrin on the basis of the results of the determination step. The prediction method further includes the step for correcting the degree of abdominal visceral fat area reduction effect on the basis of at least one piece of information of information on the subject's attributes, information on the subject's polygenic risk scores, and information on the subject's lifestyle.SELECTED DRAWING: Figure 2
Patent JP-2022543823-A (JP)
Title: カチオン性ポリマーにグラフトした複素環化合物を含む核酸分子を細胞にトランスフェクトするための組成物及びその用途
IPC: C12N15/88
Filed: 2020-08-05
Abstract: 本発明は、核酸分子を細胞にトランスフェクトするための組成物及びその用途に関する。本発明は、(i)一般式(II)の少なくとも1つの化合物、又はその互変異性体、メソマー、ラセミ体、エナンチオマー、ジアステレオマー、若しくは混合物、又はその許容される塩、及び(ii)許容される賦形剤、緩衝剤、細胞培養培地、又はトランスフェクション培地を含む、細胞、好ましくは真核細胞に核酸分子をトランスフェクトするのに適した組成物であって、式中、Y1、Y2、Y3、Z1、Z2、Z3、Z4、Z5、Z6、Z7、X1、X2、R3、P+、R、T、U及びVは本明細書で定義される通りである、組成物を対象とする。本発明はまた、前記組成物の使用、及び生細胞のインビトロ又はエクスビボのトランスフェクションのための方法に関する。
Patent JP-2022543642-A (JP)
Title: 水素吸蔵合金
IPC: C22F1/16
Filed: 2020-08-05
Abstract: 本開示は、水素を吸収及び放出することが可能なＴｉＭｎ系又はＴｉＣｒＭｎ系の水素吸蔵合金に関する。好ましい実施形態では、本開示は、フェロバナジウム（ＶＦｅ）を含む、ＴｉＭｎ系又はＴｉＣｒＭｎ系の水素吸蔵合金に関する。【選択図】 図３
Patent JP-2022544818-A (JP)
Title: 二重特異性抗体の製剤最適化
IPC: A61K47/18
Filed: 2020-08-20
Abstract: 本発明は、二重特異性抗体の製剤最適化のための方法およびシステムを提供する。本出願はまた、二重特異性抗体およびそれらの製剤最適化を構築するための分子候補を選択する方法ならびにシステムを提供する。二重特異性抗体の物理化学的パラメータが特徴付けられる。製剤最適化戦略は、相互作用パラメータの予測によって導かれる。これらの物理化学的パラメータに基づいて、様々な製剤最適化戦略が提供される。【選択図】図１
Patent JP-2022548527-A (JP)
Title: 自動車両を駆動するための方法
IPC: B60W40/105
Filed: 2020-09-08
Abstract: 本発明は、自動車両の駆動ユニットを制御するための方法に関し、本方法は、速度命令（Ｃｖ）を取得するステップと、自動車両の速度（ＶＭ）を測定するステップと、測定された速度および速度命令に基づいて前記駆動ユニットのための制御命令を計算するステップとを含む。本発明によれば、自動車両が前進していて停止させられるべきであるとき、速度命令は、厳密にゼロ未満になるように決定される。【選択図】図２
Patent JP-2022549971-A (JP)
Title: クリプトフィシン抗がん剤の生体触媒合成
IPC: C12P7/62
Filed: 2020-09-30
Abstract: 本開示は、がんの治療に有用なクリプトフィシン中間体、クリプトフィシン類似体、およびクリプトフィシンキメラ分子、ならびにこれらの化合物を生成する方法およびがんを治療する方法を提供する。【選択図】図９
Patent JP-2022554087-A (JP)
Title: プライベート転移学習
IPC: G06F21/53
Filed: 2020-10-22
Abstract: プライベート転移学習のための方法についての実施形態が開示される。本方法は、トレーニング・アプリケーション・プログラミング・インタフェース（ＡＰＩ）および推論ＡＰＩを含む機械学習モデルを生成することを含む。本方法は、所定の暗号化メカニズムを用いて機械学習モデルを暗号化することを更に含む。本方法は、暗号化された機械学習モデルを信頼された実行環境にコピーすることを更に含む。本方法は、推論ＡＰＩを用いて信頼された実行環境において機械学習モデルを実行することも含む。
Patent JP-2022554399-A (JP)
Title: 監視及び／又は治療のための皮下デバイス
IPC: A61N1/05
Filed: 2020-11-09
Abstract: 皮下に埋め込み可能なデバイスは、筋肉、骨及び／又は第１の組織に皮下に埋め込み可能なデバイスを固定するように構成されたクリップと、クリップに取り付けられた近位端及びクリップから離れて延び臓器、神経及び／又は第２の組織に接触するように構成された遠位端を有する第１のプロングと、を含む。第１のプロング上の第１の電極は、臓器、神経及び／又は第２の組織に接触するように構成される。第１の電極に導電的に接続されたワイヤは、外部デバイスに接続されるように構成され、外部デバイスは、皮下に埋め込み可能なデバイスを当該外部デバイスに電気的に接続するために、患者の身体の外部に配置される。【選択図】図３９Ａ
Patent JP-2023507943-A (JP)
Title: 新規な重水素置換ピリミジン誘導体及びこれを含む薬剤学的組成物
IPC: C07D401/12
Filed: 2020-12-15
Abstract: 本発明は化学式１で表される新規な重水素置換ピリミジン誘導体化合物またはこの薬剤学的に許容可能な塩、及びこれを含む肺癌治療用薬剤学的組成物を提供する。特に、前記化学式１で表される重水素置換ピリミジン誘導体化合物は、ＡＬＫ変異及びＥＧＦＲ変異癌細胞の成長を効果的に抑制する。
Patent JP-2023510572-A (JP)
Title: 肝細胞がんを診断するための方法
IPC: G01N33/53
Filed: 2021-01-15
Abstract: 患者における肝細胞がんを診断するための組成物、方法、およびキットが提供される。特に、メチル化無細胞ＤＮＡバイオマーカー、および患者が肝細胞がんを有するかどうかを決定するためにそれらを使用する方法が提供される。加えて、メチル化された無細胞ＤＮＡバイオマーカーは、肝硬変などの慢性肝疾患を有する肝細胞がんを有しない患者と、肝細胞がんを有する慢性肝疾患を有する患者とを区別するために使用され得る。特定されたバイオマーカーは、肝細胞がんの予後、診断、療法選択、または治療のモニタリングにおいて、単独で、または１つ以上の追加のバイオマーカーもしくは関連する臨床パラメータと組み合わせて使用され得る。【選択図】図１