baber/WOPTO huggingface dataset:
Patent JP-4127325-B2 (JP)
IPC: C07K14/78
Filed: 1996-09-13
Granted: 2008-07-30
Abstract: Biotin derivs. of formula (I), opt. (where appropriate) in D- or L-form, and their salts are new, where Q is absent, or is NH-(CH2)n-CO or NH-(CH2)n-NH; R<1> = X-Arg-Gly-Asp-Y, A-Cys(R<2>)-B-U or cyclo-(Arg-Gly-Asp-Z), Z being attached in the side chain of Q or (where Q is absent) to biotin; X, Y = an amino acid residue or a di-, tri-, tetra- or pentapeptide residue, the amino acids being selected from Ala, Asn, Asp, Arg, Cys, Gln, Glu, Gly, 4-halo-Phe, His, homo-Phe, Ile, Leu, Lys, Met, Nle, Phe, Phg, Pro, Ser, Thr, Trp, Tyr and Val and their derivs.; A is absent, or is Asp or a peptide fragment selected from Ala-Asp, Thr-Ala-Asp, Lys-Thr-Ala-Asp, Lys-Thr-Ala-Asn, Lys-Thr-Gly-Asp, Lys-Ala-Ala-Asp, Arg-Thr-Ala-Asp, Ser-Ala-Asp, Gln-Ser-Ala-Asp, Glp-Ser-Ala-Asp, Gly-Lys-Thr-Ala-Asp, Asn-Gly-Lys-Thr-Ala-Asp, Ile-Ser-Ala-Gly, Arg-Ser-Ala-Gly, Cys-Asn-Gly-Lys-Thr-Ala-Asp, Tyr-Cys-Asn-Gly-Lys-Thr-Ala-Asp, Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Ala-Asp, Asp-Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Ala-Asp, Gly-Lys-Thr-Cys(Trt)-Asp, Met-Asp-Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Ala-Asp or Asp-Met-Asp-Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Ala-Asp; B is (i) absent, (ii) OH, Ala, Asn, Asp, Arg, Cys, Gln, Glu, Gly, 4-halo-Phe, His, Ile, Leu, Lys, Met, Orn, Phe, Pro, Ser, Thr, Trp, Tyr, Val or an N-methylated deriv. of these, or (iii) a peptide fragment selected from Pro-Arg, Pro-Arg-Asn, Pro-Arg-Asn-Pro, Pro-Arg-Asn-Pro-His, Pro-Arg-Asn-Pro-His-Lys, Pro-Arg-Asn-Pro-His-Lys-Gly, Pro-Arg-Asn-Pro-His-Lys-Gly-Pro, Pro-Arg-Asn-Pro-His-Lys-Gly-Pro-Ala or Pro-Arg-Asn-Pro-His-Lys-Gly-Pro-Ala-Thr; R<2> = H, 1-6C alkyl, Trt, Dpm or Bzl; U = OH, OR<9>, NH2, NHR<9> or N(R<9>)2; Z = an amino acid residue or a di, tri- or tetrapeptide residue, the amino acids being selected from Ala, Asn, Asp, Arg, Cys, Gln, Glu, Gly, His, Ile, Leu, Lys, Met, Phe, Pro, Ser, Thr, Trp, Tyr, Val and M and derivs. of these, where the amino acid residues are linked together in peptide fashion via the  alpha -amino and  alpha -carboxy gps.; provided that an amino acid residue M is always present; M = the residue of an amino acid of formula NH(R<8>)-CH(R<3>)-COOH; R<3> = a gp. -R<5>-R<4>, -R<6>-R<4> or -R<7>-R<4>; R<4> = OH, NH2, SH or COOH; R<5> = 1-6C alkylene; R<6> = 7-14C alkylenephenyl; R<7> = 8-14C alkylenephenylalkylene; R<8> = H, 1-6C alkyl or 7-12C alkylenephenyl; R<9> = 1-6C alkyl; halo = F, Cl, Br or I; n = 1-10; Glp = pyroglutamic acid; Phg = phenylglycine; Trt = trityl; provided that when R<1> is a gp. A-Cys(R<2>)-B-U, then only one of A and B may be absent.
Patent JP-3100945-B2 (JP)
IPC: E04D13/064
Filed: 1998-09-21
Granted: 2000-10-23
Abstract: At least a portion of the filter pipe (18) which is located in the gutter (11) has an at least partly closed surface. Preferably edge regions (20, 21) running in the longitudinal direction of the slotted filter pipe are closed and smooth, being on either side of a longitudinal slot (25). The closed portions preferably extend over 1/4 to 1/2 of the circumference of the filter pipe in the gutter.
Patent JP-H0528886-B2 (JP)
IPC: H01F3/00
Filed: 1985-12-17
Abstract: 1. Lifting magnet (solenoid mechanism) with a frame-shaped yoke (1') forming the magnetic return to the armature and a winding carrier (8) incorporated within the yoke (1') and carrying the exciter winding (7), in which winding carrier (8) is located the axially movable armature (6), wherein an armature antipole (3) arranged at the bottom (2') of the yoke element (1') partially engages in the winding carrier (8), said yoke (1') being designed as a single-piece magnet frame (14) and formed as a punched and bent element from a plate blank, the angled ends (15) of which magnet frame (14) are provided with semi-circular recesses (16) which engage around the collar (10) of the winding carrier (8), characterized in that on the inward faces of the angled ends (15) of the magnetic frame (14) are located retaining lugs (17) which engage with corresponding recesses (18) formed in the top flange (9) of the winding carrier (8) when the side portions of the magnet frame are bent over the previously inserted winding carrier (8).
Patent JP-3621948-B2 (JP)
IPC: C07K19/00
Filed: 1989-10-30
Granted: 2005-02-23
Abstract: Modified proteins, modified interferons  alpha 's and  beta 's, phosphorylated modified proteins and DNA sequences encoding the above, applications and uses thereof. Modified phosphorylated Hu-IFN- alpha -like proteins are provided which carry an identifiable label such as a radio-label. Corresponding phosphorylatable Hu-IFN- alpha -like proteins which contain a putative phosphorylation site. DNA sequences which encode a Hu-IFN- alpha -like protein and contain a sequence encoding a putative phosphorylatable site. Appropriate expression vectors are used to transform compatible host cells of various microorganisms, such as E. coli. Numerous uses for the phosphorylated proteins are disclosed.
Patent JP-H06105253-B2 (JP)
IPC: G01N33/569
Filed: 1988-11-09
Abstract: A method and kit for identification of the lineages and stages of hematopoietic cells in a sample wherein the cells are treated with labeled monoclonal antibodies selected to distinguish between each lineage and maturational stages within each lineage.
Patent JP-3820013-B2 (JP)
IPC: A61F2/00
Filed: 1997-10-17
Granted: 2006-09-13
Abstract: The prosthesis consists of two plates (2, 3) made from a porous and flexible prosthetic material, joined together along a connecting line (4), esp by stitches. The two plates are asymmetrical in relation to one another, the first is more or less flat, while the second has a developed corrugated form and is anatomically shaped to conform to the lower inguinal structures, especially the spermatic and iliac vessels (11) and the psoas muscle (12). The two plates can have different levels of flexibility and can be made, for example, from a knitted or woven prosthetic material.
Patent JP-H0741839-B2 (JP)
IPC: B61L5/10
Filed: 1988-11-22
Abstract: The device comprises a geared motor (17) which drives longitudinally, via a ball screw (20) and nut, the central body (22) of a moving element comprising two slides (24, 25) sandwiching the central body (22). The two slides mesh on a common pinion mounted so as to rotate freely in the central body (22). Each slide drives, via a vertical, cylindrical floating pin (34, 35, 38, 39), a control bar (9, 10) linked to a throw rod (7, 8) which is itself linked to a switch blade. The locking of an operating bar (9, 10) is effected at the end of the travel of the central body (22) by the positioning of a floating pin in a locking groove (40 to 43) of a fixed locking plate (30, 31). A mechanical fault in the transmission chain causes a relative displacement of the slides (24, 25) with respect to the central body (22), which displacement is detected by the rotation of the common pinion integrally connected to means (27) for actuating an anomaly-control contact (29). 
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Patent JP-2968052-B2 (JP)
IPC: C12N15/00
Filed: 1990-12-18
Granted: 1999-10-25
Abstract: By means of reverse transcription of mRNA coding for a desired polypeptide, there is obtained a set of overlapping fragments of duplex cDNA, which together correspond to the whole mRNA molecule. The fragments have overlapping regions bearing sites for restriction enzymes, such that cutting and ligation gives DNA corresponding to the polypeptide. This is introduced into a vector in reading frame with a promoter. Transformation of a microorganism enables expression of the polypeptide. The construction via fragments enables large molecules to be made. Thus, human serum albumin (HSA) is produced by E. coil transformed with plasmid pHSAI. This includes DNA made from fragments derived from reverse transcription of mRNA from human liver.
Patent JP-3077908-B2 (JP)
IPC: C08F220/08
Filed: 1988-11-09
Granted: 2000-08-21
Abstract: Nitrogen-containing esters of a carboxy-containing interpolymer, wherein the interpolymer has an inherent viscosity ranging from about 0.05 to 0.30 are disclosed. The esters are useful as additives in functional fluids including transmission fluids (both automatic and manual), hydraulic fluids and gear fluids. The transmission, hydraulic and gear fluids containing the esters exhibit improved shear stability while maintaining desired high and low temperature viscosity characteristics.
Patent JP-2828339-B2 (JP)
IPC: H04B1/16
Filed: 1989-12-15
Granted: 1998-11-25
Abstract: PCT No. PCT/GB89/01544 Sec. 371 Date Aug. 8, 1991 Sec. 102(e) Date Aug. 8, 1991 PCT Filed Dec. 15, 1989 PCT Pub. No. WO90/07237 PCT Pub. Date Jun. 28, 1990.A radio data system transmits message groups comprising four blocks of which the first block always carries the program identification code for the transmitting network (P1(TN)). One type of message group, identified by a corresponding group type code (GT) in a second block always carries a program identification code for another network (PI(ON) in a fourth block and carries various corresponding items of information in a third block. Which of these various items is in the third block is identified by a user code (UC) in the second block. The items of information in the third block may in particular include alternative frequency codes for the other network identified in the fourth block.
Patent JP-3181908-B2 (JP)
IPC: F02F3/26
Filed: 1990-01-23
Granted: 2001-07-03
Abstract: A piston for a reciprocating piston internal combustion engine is provided with a reaction chamber (44, 144) communicating with a recessed area (42, 142) of the piston through a restricted continuous slot orifice (46, 146) that is configured to create a choked fluid flow condition between the combustion chamber (30, 130) and the reaction chamber at all engine operating speeds. Fuel is supplied to the reaction chamber and undergoes a controlled, cold frame reaction process while in intimate contact with the crown portion (54) of the piston (14). The reaction produces fuel radicals in sufficient quantity to seed subsequent fuel charges to properly condition the charge for predetermined desired ignition and combustion characteristics. The choking orifice (46, 146) ensures that outward flow of radicals from the reaction chamber is controlled to the extent that they will be maintained in the combustion chamber following an exhaust event of the combustion cycle so they will be available during a subsequent compression stroke of the piston for seeding the subsequent charge. The radical population in the subsequent charge conditions the charge to obtain dependable and predictable ignition in a compression ignition engine as well as knock free combustion at relatively lean air to fuel ratios in a spark ignited engine.
Patent JP-3630435-B2 (JP)
IPC: A61J15/00
Filed: 1997-06-13
Granted: 2005-03-16
Abstract: There is disclosed a medical tube for insertion into the body of a patient. The medical tube includes a tube or device suitable for insertion into the patient's body, and a permanent magnet associated therewith. The magnet may be solid or non-solid, and may be rigid or non-rigid. In one embodiment, the magnet is hollow and associated with the medical tube such that the tube may be used for its intended purposes. In another embodiment, the magnet is solid and, after insertion into the body of the patient, is displaced such that it does not interfere with the intended use of the medical tube. In a further embodiment, the magnet is removable after placement of the medical tube. <IMAGE>
Patent JP-H0720649-B2 (JP)
IPC: B29C45/64
Filed: 1991-02-05
Abstract: PCT No. PCT/EP91/00221 Sec. 371 Date Aug. 3, 1992 Sec. 102(e) Date Aug. 3, 1992 PCT Filed Feb. 5, 1991 PCT Pub. No. WO91/11314 PCT Pub. Date Aug. 8, 1991.In order to control the opening and closing movement of an injection mold (1, 3) and the feed and extraction movement of a handling device (7) for the removal of the molding in a manner which is optimally concerted with no delay, the opening movement of the mold and/or the extraction movement of the handling device is detected in relation to position and speed; if the speed lies in a reference range, a release signal is generated which triggers the feed movement of the gripping device or the closing movement of the mold.
Patent JP-H0616573-B2 (JP)
IPC: H03F3/04
Filed: 1985-09-19
Abstract: In a circuit arrangement for providing a current having a controllable temperature coefficient of current, a diffused resistor (334) is used to set up a reference current in a current source (40) which has a temperature coefficient dependent upon the diffused resistor. A current mirror (352, 354, 356) receives the reference current and passes a portion of it through an ion implanted resistor (360). The output current has a temperature coefficient which is a function of the original temperature coefficient of current and a nonzero algebraic multiple of the temperature coefficient of the implanted resistor. By appropriate selection of the resistor values and types, the temperature coefficient of the output current can be set to any desired value.
Patent JP-3252908-B2 (JP)
IPC: C08L53/00
Filed: 1992-09-07
Granted: 2002-02-04
Abstract: PCT No. PCT/GB92/01627 Sec. 371 Date Mar. 4, 1994 Sec. 102(e) Date Mar. 4, 1994 PCT Filed Sep. 7, 1992 PCT Pub. No. WO93/05113 PCT Pub. Date Mar. 18, 1993Gels made of 100 parts of Styrene-elastomer-styrene triblock copolymers and more than 300 parts of an oil which softens and extends the elastomer mid-block of the copolymer are rendered resistant to oil exudation under pressure by incorporation of a styrene-elastomer diblock copolymer. Preferred triblocks are styrene-ethylene/butylene-styrene and preferred diblocks are styrene-ethylene/propylene. Use of the gels as sealants in enclosures for electrical connections designed to hold the gel under compression is disclosed.
Patent JP-3346563-B2 (JP)
IPC: C07K19/00
Filed: 1991-03-11
Granted: 2002-11-18
Abstract: Recombinant fusion proteins which comprise a biologically active polypeptide portion and metal chelating peptide are disclosed. The fusion proteins contain metal chelating peptides which have at least three and preferably six alternating histidine residues. Fusion proteins which contain metal chelating peptides that are substrates for dipeptidylpeptidase I are als disclosed. Additionally, a method of obtaining desired polypeptides by producing recombinant fusion proteins and purifying them with immobilized metal ions is disclosed. A kit for purifying desired polypeptides is also disclosed.
Patent JP-3133059-B2 (JP)
IPC: A61F2/06
Filed: 1990-05-29
Granted: 2001-02-05
Abstract: Occlusion assembly for sealing openings in blood vessels, consisting of an occlusion element and fixing element to be fitted through the openings in the blood vessel. The fixing element is firmly connected to a retaining element. A locking element engages on the retaining element. This locking element is fitted horizontally against the outside of the blood vessel.
Patent JP-3403732-B2 (JP)
IPC: C08F10/00
Filed: 1993-10-28
Granted: 2003-05-06
Abstract: A high activity olefin polymerization catalyst catalyzes the production of polymeric lower  alpha -olefin having good properties. The catalyst is produced from an organoaluminum cocatalyst, a selectivity control agent and a novel olefin polymerization procatalyst which is prepared by contacting a tetravalent titanium halide, an optional inert diluent, an electron donor and a novel solid procatalyst precursor obtained by contacting (a) a carbonated magnesium alkoxide of the general formula   <IMAGE>   wherein R is a hydrocarbyl group having up to 12 carbon atoms and x is a number from 0.1 to about 2; and (b) at least one halogenating compound which is a non-transition metal halogenated compound or non-metallic halogenated compound. A process for polymerizing one or more  alpha -olefins utilizing the novel high activity polymerization catalyst.
Patent JP-3553083-B2 (JP)
IPC: A61K38/08
Filed: 1996-09-12
Granted: 2004-08-11
Abstract: Methods for treatment of peripheral hyperalgesia are provided, comprising administering compositions containing an anti-hyperalgesia effective amount of one or more compounds that directly or indirectly interact with peripheral opiate receptors, but that do not, upon topical or local administration, elicit central nervous system side effects. The anti-diarrheal compound 4-( rho -chlorophenyl)-4-hydroxy-N-N-dimethyl- alpha , alpha -diphenyl-1-piperidinebutyramide hydrochloride is preferred for use in the methods.
Patent JP-3168012-B2 (JP)
IPC: G10L19/00
Filed: 1996-10-25
Granted: 2001-05-21
Abstract: PCT No. PCT/EP96/04669 Sec. 371 Date May 14, 1998 Sec. 102(e) Date May 14, 1998 PCT Filed Oct. 25, 1996 PCT Pub. No. WO97/15983 PCT Pub. Date May 1, 1997Audio sources are coded by recognizing different classes of audio such as speech and music. The classes are used to select between coding algorithms and to provide object definitions. Objects have abstract and concrete classes which may further rely on parameters produced by linear prediction and subband filters to provide a frame-based bit stream of information. Each object in the bit stream has layers of information such as basic bit rate, coding parameters and enhancement parameters. The layers of information in each object allow altering selected parameters to manipulate audio signals.
Patent JP-3267973-B2 (JP)
IPC: H04R25/00
Filed: 1993-03-09
Granted: 2002-03-25
Abstract: A dual element headphone, including a first acoustic transducer mounted within a first housing so as to direct sound in a certain direction out of the first housing. The first housing is sized small enough so as to at least partially fit into the cavum concha of a listener's ear, and yet be larger in area than the entrance of the external acoustic meatus of the listener's ear. The first acoustic transducer is supported in the listener's ear so as to direct the sound generated by the transducer toward the entrance of the external acoustic meatus. A second acoustic transducer is mounted within a second housing. That second housing is substantially larger than the first housing, and overlies at least a portion of the auricle of the listener's ear. A crossover circuit divides the electrical signals received by the headphone, and transmits signals for higher frequencies to the first, smaller transducer and signals for lower frequencies to the second, larger transducer. The disclosure includes a headband and mounting plate, providing a set of these transducers for association with each ear. The first transducer may be flexibly mounted for improved comfort and sound fidelity.
Patent JP-3282812-B2 (JP)
IPC: F16B21/16
Filed: 1993-04-02
Granted: 2002-05-20
Abstract: PCT No. PCT/GB93/00674 Sec. 371 Date Feb. 27, 1995 Sec. 102(e) Date Feb. 27, 1995 PCT Filed Apr. 2, 1993 PCT Pub. No. WO93/20357 PCT Pub. Date Oct. 14, 1993.An axial locking device has locking balls which engage in a groove in a male member to lock the male member to a female member. To effect locking, a first axial movement of the male member causes it to abut an end surface on a slider and pushes slider teeth against rotor teeth, and a return movement of the male member allows the slider and rotor to return, pushed by a spring. In this way, the rotor is caused to rotate and its internal cam surface moves the locking balls. To reduce the number of parts and simplify manufacture, retaining teeth are formed by U-shaped clips on the housing of the female member, and act to prevent rotation of the slider during its axial movement, and to prevent rotation of the rotor until the rotor teeth have cleared the retaining teeth, causing a click or snap action. During the return movement of the slider and rotor, the rotor teeth cam over the ends of the retaining teeth and continue to rotate the rotor in the same direction.
Patent JP-4036478-B2 (JP)
IPC: A61F2/40
Filed: 1997-10-08
Granted: 2008-01-23
Abstract: A proximal humeral prosthesis that is particularly designed for treating a fractured humerus. The prosthesis comprises a head corresponding to the humeral head of a patient, and a stem having a proximal end to which the head is mounted. The prosthesis has a central plane coincident with the longitudinal axis of the stem about which it has a mirror axis of symmetry. One, or preferably pair of, projecting ribs are positioned at or near the proximal end of the stem adjacent the head. The projecting ribs are offset in opposite directions relative to the center plane at substantially identical offset angles (e.g., about 20 DEG  to about 40 DEG ) approximating the greater or lesser tuberosity of the humerus. Also disclosed is a method of treating a fractured humerus with this prosthesis.
Patent JP-3056252-B2 (JP)
IPC: B22D11/18
Filed: 1995-01-20
Granted: 2000-06-26
Abstract: The invention relates to a process and a continuous casting facility for the production of thin slabs, preferably of steel with a predetermined congealing thickness of (for example) 50 mm. In the said process, an optimal casting surface and internal quality, with minimal and predetermined congealing thickness and plant capacity, and thus minimal complexity of rolling material, is achieved by the optimal combination of such elements as the following: rolling of cast metal in the area of the casting guide (segment 0), cambered ingot mould with a cross-sectional area which increases from inlet to outlet, hydraulically driven lifting platform, casting powder and supply thereof, immersion discharge with specific flow cross section. Qualitative adjustment of these process and system parameters results in satisfactory supply of casting slag and circulation in the meniscus by comparison with a standard 200 mm thick slab. The conditions from the basin top to the meniscus have a direct effect on the superficial and interior quality of the casting and the reliability of the casting process.
Patent JP-3284275-B2 (JP)
IPC: C02F9/00
Filed: 1995-12-29
Granted: 2002-05-20
Abstract: PCT No. PCT/FI95/00717 Sec. 371 Date Aug. 18, 1997 Sec. 102(e) Date Aug. 18, 1997 PCT Filed Dec. 29, 1995 PCT Pub. No. WO96/20894 PCT Pub. Date Jul. 11, 1996The invention relates to a method for treating waste water sludge comprising at least one metal originating from a waste water treatment coagulant, and phosphorus and heavy metals in order to recover said at least one metal and phosphorus and to discharge said heavy metals. In this method said waste water sludge is acidified to dissolve metals contained in the sludge thereby yielding an acidified sludge solution containing at least 1% by weight of at least one metal to be recovered. In a first precipitation stage the pH of said acidified sludge solution is raised to precipitate at least one metal to be recovered as a phosphate, and thereafter the phosphate precipitate is separated, thereby leaving a solution comprising heavy metals. In a second precipitation stage the pH of said solution comprising heavy metals is raised and, if necessary, an appropriate chemical is added to precipitate heavy metals, and thereafter the precipitate is discharged.
Patent JP-4274291-B2 (JP)
IPC: C12Q1/68
Filed: 1996-12-23
Granted: 2009-06-03
Abstract: A method of measuring the activity of at least two reporter gene products in an aliquot of a sample extract is disclosed. The activities of a first and second reporter enzyme are quantified by measuring the light signal produced by degradation of a first substrate by the first reporter enzyme and the light signal produced by the degradation of a second substrate by a second reporter enzyme. Both quantifications are sequentially performed on the same aliquot of sample extract.