baber/WOPTO huggingface dataset:
Patent FI-921339-A0 (FI)
Inventor: KOHAMA TAKAFUMI C O SANKYO COM
IPC: C12R1/465
Filed: 1992-03-26
Abstract: New compounds, which we have named the "Leustroducsins" have the formula (I): <CHEM> in which R represents a 5-methylhexanoyloxy group, a 6-methyloctanoyloxy group or a 7-methyloctanoyloxy group, and salts thereof, and may be prepared by fermentation using a microorganism of the genus Streptomyces, especially a strain of the species Streptomyces platensis, such as strain SANK 60191 (FERM BP-3288). These compounds may be used for the treatment or prophylaxis of: adverse reactions resulting from cancer chemotherapy or radiotherapy; infections; cancer; cerebral dysfunction; and fungal infections.
Patent FI-923582-A0 (FI)
Inventor: BUXTON IAN RICHARD
IPC: A61K9/48
Filed: 1992-08-11
Abstract: A controlled release composition comprising spheroid cores consisting of diltiazem or a pharmaceutically acceptable salt thereof and optionally a spheronising agent, said cores being coated with a controlled release layer. The spheronising agent when present is preferably microcrystalline cellulose. Ethylcellulose is a preferred controlled release coating. The controlled release coating preferably contains a plasticiser, a surfactant and a tack-modifier.
Patent FI-932684-A0 (FI)
Inventor: RIEDESSER WALTER
IPC: D21H17/17
Filed: 1993-06-11
Abstract: To produce metal-free embossed inner liners in cigarette packs, a paper is used which consists of cellulose digested by the sulphite process, has preferably been oxygen-bleached, has a weight per unit area of about 39 to 45 g/m<2>, a filler content, preferably of calcium carbonate, of 9 to 17 % by weight, a Copp value of 20 +/- 4 g/m<2> and AKD sizing. The embossing (2) is incorporated on line on the paper machine into the still wet paper (1). An at least one-sided coating (3) of a water vapour-impermeable, flexible and recyclable copolymer of neutral odour allows optimised protection of moisture and aroma for the packed cigarettes, in particular if the coating (3) is also heat-sealable.
Patent FI-932761-A0 (FI)
Inventor: BISKUP HEIKE
IPC: A61K9/14
Filed: 1993-06-16
Abstract: PCT No. PCT/DE91/01002 Sec. 371 Date Jun. 22, 1993 Sec. 102(e) Date Jun. 22, 1993 PCT Filed Dec. 18, 1991 PCT Pub. No. WO92/11000 PCT Pub. Date Jul. 9, 1992.The invention concerns a method for the production of microscopic particles made of hydrolytically decomposable polymers, in particular copolymers, and containing active substances, using fluid gas with a uniform particle-size distribution and by the addition of biologically compatible amino acids. The microscopic particles produced by this method can be used as drugs for the treatment of humans or animals.
Patent FI-941094-A0 (FI)
Inventor: AGOURIDAS CONSTANTIN
IPC: A61K31/443
Filed: 1994-03-08
Abstract: The subject of the invention is the compounds of formula (I) <IMAGE>  in which:     - X and Y represent a hydrogen atom or together form a radical: <IMAGE>     - R represents a radical: <IMAGE> in which m represents an integer between 0 and 20, n represents a number 0, 1, 2 or 3, XA = alkyl, alkenyl, alkynyl, Hal, C IDENTICAL N, NR1R2, OR3, COR4, CO2R5, SR6, <IMAGE>  SO2R8, <IMAGE>  aryl, heteroaryl, or OC(Ar)3 and   Z = H or an acid residue.   The compounds of formula (I) have antibiotic properties.
Patent FI-942690-A0 (FI)
Inventor: BEDEL DIDIER
IPC: C08K5/00
Filed: 1994-06-08
Abstract: Composition capable of being converted into foam, comprising a mixture based on polymeric resin and an effective quantity, in relation to the said resin, of blowing agent. The blowing agent comprises at least one  alpha , beta -hydroxylated hydrocarbon azide.   Application to the production of articles made of synthetic foam.
Patent FI-942905-A0 (FI)
Inventor: SOERENSEN HANS HOLMEGAARD
IPC: A61K47/02
Filed: 1994-06-17
Abstract: A pharmaceutical formulation comprising a growth hormone and asparagine as additive or buffering substance shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved preparation at ambient temperature. The formulation may be used to treat a patient with a disorder associated with growth hormone deficiency.
Patent FI-945582-A0 (FI)
Inventor: VARASI MARIO
IPC: C07C231/10
Filed: 1994-11-28
Abstract: The invention provides new compounds of formula (I)     <IMAGE>  (I)  wherein n is an integer of 1 to 4; each of R and R1, which may be the same or different, is hydrogen, halogen, trifluoromethyl or C1-C4 alkoxy; R2 is hydrogen or C1-C4 alkyl; and a pharmaceutically acceptable salts thereof; and wherein when, at the same time, R is hydrogen, R1 is hydrogen or halogen and n is one, then R2 is other than hydrogen or methyl; and of formula (IA)    aceutical acceptable salt thereof, which are active on the central nervous system (CNS) and can be used in therapy as anti-epileptics, anti-Parkinson, neuroprotective, antidepressant, anti-spastic and hypnotic agents.
Patent FI-955354-A0 (FI)
Inventor: HANNULA ANTTI
IPC: G06F13/00
Filed: 1995-11-07
Abstract: The invention relates to methods and apparatuses for performing electronic payment transactions between a terminal equipment (100) in a telecommunication network and the other transacting party (1,2, . . . ,N). The invention utilizes a special payment service gateway (10) through which all the payment transactions of the terminal equipments in the telecommunication network are routed. The payment service gateway allows the parties of the payment transaction to support different electronic payment protocols (A, B, . . . , X) and performs the required protocol conversions so as to provide an end-to-end transaction.
Patent FI-955498-A0 (FI)
Inventor: BEAVERS MARY PAT
IPC: A61K31/445
Filed: 1995-11-15
Abstract: Nipecotic acid-derived compounds of formula (I):  telet-mediated thrombotic disorders.
Patent FI-955930-A0 (FI)
Inventor: HAY ANDREW G
IPC: B65G31/04
Filed: 1995-12-11
Abstract: An improved apparatus for transporting and metering particulate material including a transport duct having an inlet, an outlet, and at least one moving surface located therebetween having a downstream facing drive surface. The apparatus further includes a motive device for moving the moving surface between the inlet and the outlet towards the outlet. The particulate material being compacted sufficiently to cause the formation of a bridge composed of substantially interlocking particulates spanning the width of the transport duct. The bridging of the particulates causes the particulates to become semi-hydrostatic in nature such that the force exerted by the downstream facing drive surface upon particulates within the transport duct drives the entire mass of material through the transport duct towards the outlet. The apparatus is used to transport and meter particulate material under ambient conditions and against pressure.
Patent FI-960123-A0 (FI)
Inventor: LESIEUR DANIEL
IPC: A61P25/24
Filed: 1996-01-10
Abstract: Hetero-cycloalkyl derivs. of formula (I) and their enantiomers and diastereoisomers are new. R1 = alkyl opt. substd. by Q; or cycloalkyl or cycloalkylalkyl, both opt. substd. by Q'; A together with the benzene gp. = tetrahydronaphthalene, dihydronaphthalene, naphthalene, benzothiophene, 2,3-dihydrobenzothiophene; or indoline or indole both opt. N-substd. by Ra, CORa or CO2Ra; Ra = alkyl, Ph or phenylalkyl; R2 = H or alkyl; R3 = C(=X)R4 or C(=X')NHR5; X, X' = S or O; R4 = H, alkenyl, alkynyl, alkyl opt. substd. by Q, or cycloalkyl or cycloalkylalkyl both opt. substd. by Q'; R5 = H, alkyl opt. substd. by Q, or cycloalkyl or cycloalkylalkyl both opt. substd. by Q'; alkyl, alkoxy = 1-6C; alkenyl, alkynyl = 2-6C; cycloalkyl = 3-8C; Q = halo, OH, alkyl or alkoxy; Q' = halo, alkyl or oxo.
Patent AP-9901473-A0 (AP)
Title: Use of benzopyranols to treat neurological disorders.
Inventor: PARSONS ANDREW
IPC: A61K31/35
Filed: 1997-09-15
Abstract: Benzopyran derivatives and analogs are disclosed as useful for the treatment and/or prophylaxis of degenerative diseases such as huntingdon's chorea, schizophrenia, nuerological deficits associated with aids, sleep disorders (including circadian rhythm disorders, insomnia and narcolepsy), tics (e.G. gilles de la tourette's syndrome), traumatic brain injury, tinnitus, neuralgia, especially trigeminal neuralgia, neuralgia, neuropathic pain, dental pain, cancr pain, nappropriate neuronal activity resulting in neurodysthesias in diseases such as diabetes, ms and motor neurone disease, ataxias muscular rigidity spasticity), tempooromandinbular joint dysfunction
Patent IL-70250-A0 (IL)
Title: Stretchable composite articles and process for their production
IPC: D06N3/18
Filed: 1983-11-16
Abstract: @ This invention provides a waterproof and breathable elastomeric polytetrafluoroethylene layered article or fabric for use in rainwear or other protective articles. The layered article can for example, exhibit elastomeric properties of stretch to break of 275% in the machine direction, and 145% in the transverse direction and a total stretch recovery of at least 39% after being stretched to 75 % extension for 100 cycles. The waterproof and breathable elastomeric polytetrafluoroethylene layered article can be bonded to a stretch fabric to form a composite fabric which is durable and possesses a moisture vapor transmission rate exceeding 1000 gms/m<sup>2</sup>/day, and preferably above about 2000 gms/m<sup>2</sup>/day.
Patent IL-90205-A0 (IL)
Title: Carbonation apparatus
IPC: B67D1/00
Filed: 1989-05-05
Abstract: A connector for a bottle of concentrate for a carbonating apparatus has a cylindrical body the upper end of which carries a structure defining a number of radially extending baffle and a central opening through which a dip tube may be inserted into the bottle. A latching ring for connecting the connector to the carbonation apparatus is carried by the body at a position outwardly thereof and lower than the baffle structure. The latching ring is constructed to snap on to a corresponding boss on the carbonation apparatus. The bottle is detached from the carbonation apparatus, after exhaustion of the contents, by removal of a tear-off strip which connects the latching ring to the body of the connector. To facilitate connection of a fresh bottle of concentrate to the apparatus, the apparatus includes a housing which is detachable from the remainder of the apparatus and which carries the dip tube and other elements co-operable with the connector for attaching the bottle.
Patent IL-92028-A0 (IL)
Title: Pyridine derivatives
IPC: A61P29/00
Filed: 1989-10-17
Abstract: The invention concerns novel, pharmaceutically useful 1,3-dioxane alkenoic acid derivatives of the formula I containing a pyridyl moiety at position 4 of the dioxane ring and in which the groups at positions 2, 4 and 5 have cis-relative stereochemistry, X is hydrogen, alkoxy or hydroxy, Y is vinylene, n is 1 or 2, A<1> is alkylene, the substituents R<1> and R<2> at position 2 of the dioxane ring have a variety of values defined hereinafter, and R<4> is hydroxy, a physiologically acceptable alcohol residue or alkanesulphonamido, and the pharmaceutically acceptable salts thereof. The invention also includes processes for the manufacture and use of the acid derivatives as well as pharmaceutical compositions for therapeutic use in one or more of a variety of diseases such as ischaemic heart disease, cerebrovascular disease, asthmatic disease and/or inflammatory disease. <CHEM> l
Patent IL-96365-A0 (IL)
Title: Method and composition for treating inflammatory bowel disorders comprising fatty acids
IPC: A61K31/19
Filed: 1990-11-16
Abstract: A method for the treatment of inflammatory bowel disorders, together with a pharmaceutical composition comprising short chain fatty acids that is useful therein, is described in this invention. The administration of short chain fatty acids of about 2 to about 6 carbon-length to patients afflicated with inflammatory bowel disorders is shown to effectively alleviate the symptoms of the treated disorder.
Patent IL-97426-A0 (IL)
Title: 3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions
IPC: A61K31/5377
Filed: 1991-03-04
Abstract: Antiglaucoma compositions containing 3-arylcarbonyl-1-aminoalkyl-1H-indoles, as the active component thereof, and a method of use thereof in the treatment of glaucoma. Also included are novel 3-arylcarbonyl-1-aminoalkyl-1H-indoles.
Patent FI-20030241-A0 (FI)
Inventor: JOKELA PEKKA
IPC: C10J3/66
Filed: 2003-02-17
Abstract: The invention relates to a method for producing synthesis gas from ash-containing solid feedstock material. According to the invention, the comminuted and dried biomass feedstock is pyrolyzed and the thus obtained pyrolysis gases are gasified with the help of oxygen gas. The char is combusted in a separate combustion chamber. The result is good-quality synthesis gas suitable for use as raw material in the production of traffic fuels.
Patent IL-100439-A0 (IL)
Title: Novel pesticidal compositions derived from neem oil and neem wax fractions
IPC: A01N65/00
Filed: 1991-12-20
Abstract: Novel pesticide formulations prepared from neem seeds are disclosed. Two distinct fractions are derived from non-polar, hydrophobic solvent neem seed extracts which are substantially free of azadirachtin, by removing the hydrophobic solvent and cooling the resulting neem oil to form a semi-solid neem wax fraction and a clarified neem oil fraction.
Patent IL-102823-A0 (IL)
Title: Bidirectional parallel protocol
IPC: G06F13/42
Filed: 1992-08-16
Abstract: A protocol provides bidirectional communication capability between a host computer and a printer over a parallel interface, the host computer and the printer having a forward channel therebetween for the transfer of signals from the host computer to the printer. The protocol includes conventions for turning the forward channel around so as to establish a reverse channel to allow transfer of data from the printer to the host computer, conventions for controlling the transfer of data from the printer to the host computer over the reverse channel, and conventions for turning the reverse channel back around so as to re-establish the forward channel. <IMAGE>
Patent IL-103076-A0 (IL)
Title: Bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid
IPC: C12R1/38
Filed: 1992-09-07
Abstract: (A) A novel process for preparing 7-aminodesacetoxy cephalsporanic acid (7-ADCA) is claimed comprising (a) maintaining in a culture medium capable of sustaining its growth, a strain of Penicillium chrysogenum (PC) which produces isopenicillin N (IPN) and adding to the culture medium an adipate feedstock comprising adipic acid or one or more of its salts and esters which are capable of being assimilated and utilised by the strain of PC to produce adipoyl-6-amino penicillanic acid (adipoyl-6-APA), where the strain of PC has been transformed by DNA encoding the activity of the expandase enzyme capable of accepting the adipoyl-6-APA as a substrate so that as a result of its expression, the adipoyl-6-APA produced by the strain is in situ ring expanded to form adipoyl-7-ADCA and (b) contacting the adipoyl-7-ADCA with an adipoyl cyclase whereby the adipoyl side chain is removed and 7-ADCA is formed which is then isolated. Also claimed are: (B) a recombinant DNA expression vector comprising DNA encoding the activity of the expandase enzyme derived from Streptomyces clavuligerus (S.C) ATCC 27064 and a promoter which drives expression of the expandase activity-encoding DNA comprising the promoter of the PC IPN synthetic (IPNS) gene; (C) a PC host cell transformed with a recombinant DNA expression vector as in (B).
Patent IL-105347-A0 (IL)
Title: Multiple sclerosis t-cell receptor
IPC: A61K38/39
Filed: 1993-04-09
Abstract: Peptides derived from fragment 84-102 of hMBP by deleting one to four N-terminal amino acids and/or one to eight C-terminal amino acids and containing an alanine residue at position 85,86,87,88,89,90,91,92,93,94,95,96,97,98, or 99.These peptides are useful to suppress autoimmune responses.
Patent IL-109802-A0 (IL)
Title: Pharmaceutical agents for treatment of emesis
IPC: C07D453/02
Filed: 1994-05-26
Abstract: The present invention relates to compounds useful for treating or preventing emesis in mammals, including humans, using certain quinuclidine derivatives, piperidine derivatives, azanorbornane derivatives and related compounds.
Patent IL-110667-A0 (IL)
Title: Bowed framed membrane, its preparation and use in electrophoresis
IPC: G01N33/50
Filed: 1994-08-15
Abstract: A bowed framed membrane is disclosed for use in automated direct blot electrophoresis and subsequent membrane process steps to develop a chemiluminescent image of the resultant blot of selected fragments and to detect that image. A frame made from a thin rigid plastic plate such as polyethylene is provided with a window. A membrane covers that window and is bonded on two opposing sides only while the frame is held in a bowed condition. The membrane is maintained under tension during processing by the bowing permitting processing at the elevated temperatures used in molecular biological procedures without loss of flatness. Processes for preparing such frames and various utilities are also disclosed.
Patent IL-111257-A0 (IL)
Title: Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
IPC: C07D401/14
Filed: 1994-10-12
Abstract: A method of inhibiting Ras function and therefore inhibiting cellular growth is disclosed. The method comprises the administration of a compound containing a tricyclic ring system to a biological system. In particular, the method inhibits cellular growth in a mammal such as a human being. Novel compounds of formula (4.0) are disclosed. Also disclosed are processes for making 3-substituted compounds of formula (4.0). Further disclosed are novel compounds which are intermediates in the processes for making the 3-substituted compounds of formula (4.0).
Patent IL-139255-A0 (IL)
Title: A support member
IPC: E04B1/58
Filed: 1998-04-27
Abstract: A support member includes an elongate member (2, 3) being a side wall (30) adapted to be located adjacent an end of a structure (1) to be supported. The side wall (30) includes a number of engagement means (22, 24) which permit a tie member (7) to be mounted on the side wall (30). The tie member (7) has a portion (23) projecting from the side wall (30) to engage with the structure (1) to be supported.
Patent IL-139354-A0 (IL)
Title: Method for making hydroxy-25-ene-vitamin d compounds
IPC: C07C/
Filed: 1999-05-28
Abstract: The present invention provides a method for preparing a novel class of vitamin D compounds in which the C-25 or equivalent position has a double bond. In addition, the side chain is optionally extended by one or two methylene or methyne groups. The compounds prepared by the method of the present invention are of value as prodrugs for active 1alpha, 24-dihydroxylated vitamin D compounds.
Patent IL-144893-A0 (IL)
Title: Method for the purification, recovery, and sporulation of cysts and oocysts
IPC: A61K/
Filed: 2000-02-25
Abstract: A vaccine for in ovo vaccination against avian coccidiosis produced by a method including obtaining the coccidial oocysts from a fecal suspension, homogenizing the fecal suspension, separating the oocysts from the fecal debris by either salt flotation using sodium sulfate or gas flotation using air, sporulating the oocysts using hydrogen peroxide and air sparging, bleaching the sporulated oocysts, washing the bleached oocysts, concentrating the sterile washed oocysts and combining the concentrates of various species of coccidial oocysts, and producing a vaccine. The method in whole or in part can be applied to other kinds of encysted protozoa to produce vaccines for various types of animals.
Patent IL-146483-A0 (IL)
Title: Method for stabilizing hydrogen peroxide
IPC: D06L3/02
Filed: 2000-06-03
Abstract: The invention relates to the use of one or more alpha-keto carboxylic acid esters and/or aldehyde carboxylic acid esters for stabilizing hydrogen peroxide during enzyme-catalyzed or metal-catalyzed oxidation reactions in organic synthesis, as well as for stabilizing hydrogen peroxide or aqueous or organic hydrogen peroxide solutions during production, storage and transport.
Patent IL-148755-A0 (IL)
Title: Device for heat transfer between two walls
IPC: F24S23/00
Filed: 2000-09-20
Abstract: The invention concerns a heat transfer device comprising an insulating module (12) designed to be inserted between a first wall (14) and a second wall (16) to define a closed loop wherein flows a heating medium (FC) which comprises a first channel (28) extending substantially vertically along the first wall (14) and a second channel (30) extending substantially vertically along the second wall (16), the first channel and the second channel being mutually offset in the vertical direction to define a low channel and a high channel, as well as an upper channel (32) and a lower channel (34) linking the first channel and the second channel, such that heating medium (FC) flows freely or is blocked naturally in the loop when on the basis of the respective temperatures of the high channel and the low channel. The invention is particularly useful for heating or cooling buildings.
Patent IL-165686-A0 (IL)
Title: Radiation detector
IPC: C30B9/00
Filed: 2003-06-10
Abstract: A method of forming a radiation detector compound comprising: (a) providing a mixture of Cd, Zn and Te; (b) heating the mixture to a liquid state; (c) adding to the liquid mixture a first dopant that adds shallow level donors (electrons) to the top of an energy band gap of said mixture when it is solidified; (d) adding to the liquid mixture a second dopant that adds deep level donors and/or acceptors to the middle of said band gap of said mixture when it is solidified; and (e) solidifying said mixture including said first and second dopants to form the compound.
Patent IL-194318-A0 (IL)
Title: Beta-galactosidase with transgalactosylating activity
IPC: A23L33/00
Filed: 2008-09-24
Abstract: The present invention concerns a new β-galactosidase with transgalactosylating activity isolated from Bifidobacterium bifidum. The β-galactosidase is capable of converting lactose to a mixture of galactooligosaccharides which are β-linked and unexpectedly produces the α-linked disaccharide galactobiose. The mixture may be incorporated into numerous food products or animal feeds for improving gut health by promoting the growth of bifidobacteria in the gut, and repressing the growth of the pathogenic microflora.
Patent IL-196907-A0 (IL)
Title: Glycoprotein synthesis
IPC: A61K38/14
Filed: 2009-02-05
Abstract: Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.
Patent IL-200700-A0 (IL)
Title: System for 3d image projections and viewing
IPC: H04N13/363
Filed: 2009-09-02
Abstract: The present inventions relates to 3D viewing glasses, comprising a right channel non-spherical lens with a right channel spectral separation filter and a left channel non-spherical lens with a left channel spectral separation filter, wherein the filters are spectrally complementary to each other, are not uniform across the lenses and comprise a dielectric coating configured to red shift the filter characteristics at edges of the filters such as to compensate for a blue shift caused by an angle change at the edges of the field of view through the filters. The present invention further relates to a use of said 3D viewing glasses for viewing spectrally separated images, wherein at least one of the spectrally separated images is produced using 5 light wavelength bands.