Patent SG-11201803768W-A (SG)
Title: Methods and compositions for preventing or treating cancer
Inventor: SCHIFFMAN JOSHUA
IPC: C07K14/47
Filed: 2016-10-07
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization 1111111101111011101010111110101111111110111010101111101111101111101111011111 International Bureau .. .... ..Yejd (10) International Publication Number (43) International Publication Date ..... ...r .....1 13 April 2017 (13.04.2017) WI P0 I P CT WO 2017/062726 Al (51) International Patent Classification: (74) Agents: LANGER, Michael et al.; 180 N. Stetson Ave., A61K 45/06 (2006.01) A61L 29/16 (2006.01) Suite 2000, Chicago, Illinois 60601 (US). A61K 48/00 (2006.01) A61L 31/16 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, (21) International Application Number: AO, PCT/US2016/055921 BZ, DO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DZ, EC, EE, EG, ES, FL GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, 7 October 2016 (07.10.2016) KW, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, (25) Filing Language: English MG, OM, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (26) Publication Language: English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, (30) Priority Data: TN, 62/239,103 8 October 2015 (08.10.2015) US ZW. TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, 62/379,179 24 August 2016 (24.08.2016) US (84) Designated States (unless otherwise indicated, for every (71) Applicants: UNIVERSITY OF UTAH RESEARCH kind FOUNDATION [US/US]; 615 Arapeen Drive, Suite #310, GM, Salt Lake City, Utah 84108 (US). TECHNION RE- TZ, of regional protection available): ARIPO (BW, GH, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, SEARCH & DEVELOPMENT FOUNDATION LIM- TJ, ITED [IL/IL]; Malat Building, Floor no. 5, Technion City, DK, 3200004 Haifa (IL). LV, SM, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, — _ (72) Inventors: SCHIFFMAN, Joshua; 1387 S. Ambassador GW, KM, ML, MR, NE, SN, TD, TG). Way, Salt Lake City, Utah 84108 (US). SCHROEDER, Avi; Technion - Israel Institute of Technology, Room: 351, Published: 32000 Haifa (IL). ABEGGLEN, Lisa; 862 East 600 — with international search report (Art. 21(3)) South, Salt Lake City, Utah 84102 (US). = [Continued on next page] = (54) Title: METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING CANCER = = = = Figure I = = = = = _ 11 ei ei 0 IN 1-1 (57) : The present disclosure is directed to methods and compositions for inhibiting a cancer cell using nucleic acid se - 0 quences encoding elephant p53 or elephant p53 amino acid sequences. ei 0 WO 2017/062726 Al IMIOHOMMIDIIM01011110111010MOHEMOVOIS — before the expiration of the time limit for amending the — with sequence listing part of description (Rule 5.2(a)) claims and amendments to be (Rule republished 48.2(h)) in the event of receipt of