baber/WOPTO huggingface dataset:
Patent BR-PI1010931-B1 (BR)
Title: Sistema de cateter de ablação com um balão
Inventor: AKINORI MATSUKUMA
IPC: A61B18/12
Filed: 2010-05-18
Abstract: sistema de cateter de ablação com um balão é provido um fio guia para um cateter de ablação com um balão a fim de impedir que a ponta do fio guia fique indevidamente aquecida quando o tratamento de ablação for realizado usando o cateter de ablação com o balão e o fio guia. é especificamente provido um fio guia, em que uma porção deformada formada dobrando e/ou curvando o fio guia fica localizada na região de 20-100 mm da ponta na direção longitudinal do fio guia e, na porção deformada, a menor distância entre o eixo central na direção longitudinal do fio guia e um ponto que é mais afastado na direção perpendicular ao eixo central é maior ou igual ao diâmetro interno mínimo de um lúmen de um eixo do cateter de um cateter de ablação com um balão usado em combinação com o fio guia, e menor ou igual a 40 mm.
Patent BR-PI1014343-B1 (BR)
Title: Disco de freio, especialmente disco de freio ventilado, com um anel de fricção
Inventor: GUENTHER SCHWARZ
IPC: F16D65/12
Filed: 2010-03-01
Abstract: disco de freio. a presente invenção refere-se a um disco de freio (10) que é conformado com um anel de fricção (12) e um vaso de disco (11), unido com o anel de fricção (12). entre os dois discos de freio (12a, 12b) é conformado um filete de suporte (21), no qual se encontram recortes (25). nestes recortes (25) pode penetrar uma corrente de ar de resfriamento, que elimina o calor gerado no processo da frenagem.
Patent BR-PI1100758-B1 (BR)
Title: solução de tratamento de madeira e método para reduzir a decomposição por insetos e microbiana em madeira
Inventor: GORDON MURRAY
IPC: B27K3/52
Filed: 2011-01-06
Abstract: TRATAMENTO DE MADEIRA DE ETAPA UNICA COM CREOSATO/BORATO Expõe-se um método para reduzir a decomposição por insetos e microbiana na madeira. O método compreende as etapas de: a) mergulhar a madeira em uma solução de tratamento que compreende 1) um éster de C1-C6 monoalcanolamina de ácido bórico (por exemplo, éster de monoetanolamina de ácido bórico) e ii) creosoto; e b) expor a madeira mergulhada proveniente da etapa a) a condições que causam a liberação de boro a partir do éster de C1-C6 monoalcanolamina de ácido bórico (éster de monoetanolamina de ácido bórico) e que faz com que o boro migre para o interior da madeira.
Patent BR-PI1103392-B1 (BR)
Title: Processo de produção de pigmentos nanoestruturados à base de óxido de alumínio nas cores azul, amarelo, rosa e verde
Inventor: CELSO HIROSHI HAYASI
IPC: C09C1/40
Filed: 2011-06-30
Abstract: patente de invenção de processo de produção de pigmentos nanoestruturados a base de oxido de alumínio nas cores azul, amarelo, rosa e verde. problema: criação de pigmentos nanoestruturados através de uma rota simples, com apenas trés etapas, e a baixa temperatura de 600 graus celsius. processo: produção de pigmentos nanoestruturados a base de óxido de alumínio nas cores azul, amarelo, rosa e verde, a qual pode ser aquecida em forno a temperaturas acima de 1200 °c.
Patent BR-PI9808485-B1 (BR)
Inventor: KHAN MOHAMMAD A
IPC: A61L15/44
Filed: 1998-03-31
Abstract: An antimicrobial film forming surgical site preparation composition includes a film forming material and an antimicrobial agent soluble in a fugitive solvent. The composition when applied to the skin surface forms a substantially water insoluble, substantially tack-free flexible film adherent to the skin surface. The film is capable of releasably retaining the antimicrobial agent to substantially inhibit microbial growth on the skin surface. The film releases sufficient antimicrobial agent to substantially eliminate the microorganisms normally present on the skin surface to prepare the surface for the procedure and continues to release the antimicrobial agent during the procedure and subsequent wound healing. The composition can be easily washed from fabric and does not stain the fabric even where the fabric is treated with chlorine bleach. In addition, a smooth continuous film is formed without the use of a separate plasticizer.
Patent EA-002149-B1 (EA)
Title: Improved methods for processing activated protein c
Inventor: BAKER JEFFREY CLAYTON
IPC: C12N9/64
Filed: 1998-04-24
Abstract: 1. An improved method of freeze drying an aqueous solution of recombinant activated protein C, comprising conducting such freeze drying at an ionic strength of greater than 150mM and a pH of about 5.5 to less than 6.3. 2. The method of claim 1 wherein protein C is human activated protein C. 3. The method of claim 2 wherein the pH is from 5.6 to 6.2. 4. The method of claim 3 wherein such solution comprises sodium chloride. 5. The method of claim 4 wherein the sodium chloride concentration is 200mM to 1000mM. 6. The method of claim 1 wherein the pH is buffered with sodium citrate. 7. A preparation of activated protein C obtainable by freeze drying a solution of activated protein C having an ionic strength of greater than 150mM and a pH of about 5.5 to less than 6.3, in the absence of a denaturing agent, histidine, lysine hydrochloride or albumin. 8. An aqueous solution of recombinant activated protein C, comprising recombinant activated protein C; said solution having an ionic strength of greater than 150mM and a pH of about 5.5 to less than 6.3 having less than 10% des(1-9) activated protein C and des(1-10) activated protein C by combined weight. 9. A pharmaceutical formulation comprising recombinant activated protein C; said formulation having less than about 10% des(1-9) activated protein C and des(1-10) activated protein C by combined weight. 10. A pharmaceutical formulation of claim 9; said formulation having less than about 5% des(1-9) activated protein C and des(1-10) activated protein C by combined weight.
Patent EA-007487-B1 (EA)
Title: Method for preparing a glucosamine
Inventor: PINZA MARIO
IPC: A61K31/7008
Filed: 2002-12-02
Abstract: Method for preparing a compound comprising protonated glucosamine and Cl, Naand SOions, in which (a) glucosamine hydrochloride and a stoichiometric excess of sodium sulphate are placed in water, (b) the mixture obtained from the preceding step (a) is heated, (c) the mixture is cooled, and (d) the solid present in the said cooled mixture is recovered by filtration. Compound comprising protonated glucosamine and Cl, Naand SOions and having the X-ray diffraction diagram of Fig. 1.
Patent EA-005999-B1 (EA)
Title: A transport trolley having pivotable roller housings
Inventor: RAETZE BERND
IPC: B66F9/06
Filed: 2003-02-12
Abstract: A low-rise trolley to transport palletised cargo 12-18 meters in length and weighing in excess of 30 tonnes has two parallel forks each supported by two or three sets of rollers 7-13. Respective hydraulic cylinders 140 extend and retract each set of rollers 7-13 with respect to its housing 6 so that loads may be lifted by the trolley. Each housing 6 is pivotally mounted at 115 to its respective fork so as to allow rollers 7-13 to remain in contact with uneven ground.
Patent EA-007303-B1 (EA)
Title: Generating acid downhole in acid fracturing
Inventor: STILL JOHN
IPC: C09K8/72
Filed: 2003-10-24
Abstract: An acid fracturing method is provided in which the acid is generated in the fracture by hydrolysis of a solid acid-precursor selected from one or more than one of lactide, glycolide, polylactic acid, polyglycolic acid, a copolymer of polylactic acid and polyglycolic acid, a copolymer of glycolic acid with other hydroxy-, carboxylic acid-, or hydroxycarboxylic acid-containing moieties, and a copolymer of lactic acid with other hydroxy-, carboxylic acid or hydroxycarboxylic acid-containing moieties. The solid acid-precursor may be mixed with a solid acid-reactive material to accelerate the hydrolysis and/or coated to slow the hydrolysis. Water-soluble liquid compounds are also given that accelerate the hydrolysis. The method ensures that the acid contacts fracture faces far from the wellbore.
Patent EA-013677-B1 (EA)
Title: Human monoclonal antibodies against cd25 and use thereof
Inventor: SCHUURMAN JANINE
IPC: G01N33/68
Filed: 2003-11-14
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Patent EA-010320-B1 (EA)
Title: A filling plant
Inventor: WESTHUES RAINER
IPC: B65B59/04
Filed: 2005-06-29
Abstract: Filling machine and filling unit for a filling machine for filling sacks, comprising a receiving device (10), a charging pipe (12) on which the sack to be filled can be put, a charging pipe support (14) and a measuring device (17). The invention is characterized in that the receiving device (10) forms a modular unit with the measuring device (17) and the charging pipe support (14).
Patent EA-011281-B1 (EA)
Title: Macrolides
Inventor: CHUPAK LOUIS STANLEY
IPC: C07H17/08
Filed: 2005-12-12
Abstract: Macrolide compounds per se, as shown below and defined herein, and their use, e.g., as antibacterial and antiprotozoal agents in animals, including humans: Formula (I). Also disclosed are methods of preparing the compounds, intermediates, and pharmaceutical compositions thereof, and methods of treating or preventing disease by administering the compounds to subjects in need. This abstract is only an excerpt and is not limiting of the invention.
Patent EA-013634-B1 (EA)
Title: Methods and nucleic acids for analyses of cellular proliferative disorders
Inventor: DISTLER JUERGEN
IPC: A61J1/00
Filed: 2006-04-17
Abstract: Aspects of the invention provide methods, nucleic acids and kits for detecting, or for detecting and distinguishing between or among liver cell proliferative disorders or for detecting, or for detecting and distinguishing between or among colorectal cell proliferative disorders. Particular aspects disclose and provide genomic sequences the methylation patterns of which have substantial utility for the improved detection of and differentiation between said class of disorders, thereby enabling the improved diagnosis and treatment of patients.
Patent EA-015171-B1 (EA)
Title: Treatment of chronic kidney disease (ckd) subjects using lanthanum compounds
Inventor: PRATT RAYMOND DAVIS
IPC: A61K33/244
Filed: 2006-11-07
Abstract: A subject with symptoms of chronic kidney disease (CKD), who does not have end-stage renal disease (ESRD), can be treated by orally administering a pharmaceutical composition as an active ingredient a therapeutically effective amount of a non-toxic lanthanum compound. Administration of a lanthanum compound can prevent the progression of CKD, treat soft tissue calcification, and treat secondary hyperparathyroidism.
Patent EA-013765-B1 (EA)
Title: Lubricant or hydraulic pump
Inventor: PALUNCIC ZDRAVKO
IPC: F16N13/22
Filed: 2007-03-15
Abstract: The invention relates to a lubricant or hydraulic pump for delivering oil or the like having a housing (1) which is formed from two housing shells (2, 3) which are of at least substantially similar or identical construction. An inlet (7) is provided on or in the housing (1). Furthermore, a rotatably mounted drive element, which is configured, in particular, as a swash plate (17), and at least one pump element (5) which interacts with the drive element (17) to deliver oil or the like are arranged in the housing (1).
Patent EA-018607-B1 (EA)
Title: Use of lacosamide for treating refractory status epilepticus
Inventor: STOEHR THOMAS
IPC: A61K31/55
Filed: 2007-06-15
Abstract: The present invention relates to novel drugs of refractory Status epilepticus, that is a disease condition which substantially or at least partially refractory against one or more drugs which are usually employed in the treatment of Status epilepticus or/and epilepsy, said drugs are also applicable for the treatment or even prevention remote sequences of the refractory Status epilepticus, to which relates to neuron damage and epileptogenesis. Use of (R)-2-acetamido-N-benzyl-3-methoxypropionamide (lacosamide) is proposed for preparing a pharmaceutical composition which can be used for prevention, alleviation or/and treatment of refractory Status epilepticus. The lacosamide can also be used for prevention, alleviation or/and treatment of epileptogenesis. A pharmaceutical composition is further proposed comprising lacosamide and, at least, one benzodiazepine.
Patent EA-018778-B1 (EA)
Title: Loop reactor suitable for olefin polymerization with improved product removal means
Inventor: FOUARGE LOUIS
IPC: B01J19/18
Filed: 2008-08-29
Abstract: The present invention relates to a loop reactor suitable for olefin polymerization process comprising: a plurality of interconnected pipes defining a flow path for a polymer slurry, said slurry consisting essentially of an olefin reactant, a polymerization catalyst, liquid diluent and solid olefin polymer particles, means for introducing olefin reactant, polymerization catalyst and diluent into said reactor, a pump suitable for maintaining the polymer slurry in circulation in said reactor, and single settling leg connected to said loop reactor through (a) a take off line extending from said reactor to said settling leg and configured to remove said polymer slurry from said reactor, and (b) a return line extending from said settling leg to said reactor, characterized in that said take off line is radially connected to said single settling leg.
Patent EA-018088-B1 (EA)
Title: Imidazolyl biphenyl imidazoles as hepatitis c virus inhibitors
Inventor: BACHAND CAROL
IPC: A61K31/41
Filed: 2008-02-13
Abstract: The present disclosure relates to compounds of Formula (I), compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
Patent EA-017723-B1 (EA)
Title: A beverage sterilisation device
Inventor: RASMUSSEN JAN NORAGER
IPC: A23L3/32
Filed: 2008-10-24
Abstract: A beverage sterilisation device comprises a housing defining an inner space, and having a first and a second end. An electrically insulated fluid path-defining conduit extends through the inner space from the first end to the second end. A first electrode has a first part positioned adjacent to the fluid path and a second part extending perpendicular to the first part. A first counter electrode defines together with the first electrode a first capacitor, and a second electrode having a third part and a fourth part. The third part is positioned adjacent to the fluid path, and the fourth part extends substantially perpendicular to the third part. A second counter electrode defines together with the second electrode a second capacitor. The first counter electrode and the second counter electrode are short-circuited by an electrical connection, and a conductive device is electrically connected between the first electrode and the second electrode. A first trigger point is defined at the second part and remote from the first part, and a second trigger point is defined at the first counter electrode opposite to the first trigger point. The device further comprises an electrical activation circuit for short-circuiting the pair of trigger points and for causing an electric field to propagate from the first trigger point and along the fluid path.
Patent EA-019743-B1 (EA)
Title: Toggle-action dispensing closure with articulated rear flange
Inventor: DOMOY BRETT CHRISTOPHER
IPC: B65D47/20
Filed: 2010-04-22
Abstract: A toggle-action dispensing closure (10) is provided for manipulation between a closed, non-dispensing orientation and an open, dispensing orientation that is easily assembled, resists inadvertent opening and has an improved aesthetic appearance for variously shaped closures. The closure includes an actuator (50) rotationally mounted on a housing (14) whereby the housing may be secured to a container (200). The axis of rotation of the actuator is asymmetrically disposed in the housing. The actuator has a rear flange (55) with an articulatable hinge (57) that is longer than its front flange (54). When the closure is securely mounted to a container, the portion (93) of the rear flange below the hinge resiliently contacts the container assisting in preventing inadvertently opening the closure.
Patent EA-020555-B1 (EA)
Title: Impeller for mixing slurry in metallurgical processes
Inventor: LILJA LAUNO
IPC: B01F27/91
Filed: 2010-03-01
Abstract: The invention relates to a turbine-type high-power impeller, to be used for mixing slurry in hydrometallurgical process reactors. The impeller is formed of at least five blades, each of which blades comprises a front edge, trailing edge, root and tip; the roots of the impeller blades are permanently attached by a joint to the hub or axis of the impeller, so that the front edge of the impeller blade is straight, and the trailing edge is chamfered, in which case the blade is narrowed towards the tip, and the blade is provided with two longitudinal folds arranged in parallel with the front edge of the blade.
Patent EA-024510-B1 (EA)
Title: Process and plant for treating ore concentrate particles containing valuable metal
Inventor: HOLMSTROEM AAKE
IPC: C22B11/02
Filed: 2010-12-14
Abstract: The present invention concerns a process and a plant for treating ore concentrate particles containing valuable metal and having at least arsenic and sulfur containing components. The process comprises a two-stage roasting process comprising a first roasting step (1) made in a first roasting reactor (16) and a second roasting step (3) made in a second roasting reactor (17). A gas mixture is formed from the first process gas component (2) obtained from the first roasting step (1) and from the second process gas component (4) obtained from the second roasting step (3). Post combustion of the gas mixture is made in a post combustion chamber (6). The post combustion operates with said reducing and sulphide rich first process gas component (2) and the second process gas component (4) as oxidizer gas in order to decompose SOin the gas mixture to reduce the SOcontent. The risk of accretion formation and corrosion in the post combustion chamber and in subsequent steps is reduced. Finally the exit gas (7) is exposed to subsequent gas cooling and dust removal steps (8 to 11).
Patent EA-026368-B1 (EA)
Title: Hepatitis b antiviral agents
Inventor: HARTMAN GEORGE D
IPC: C07D241/18
Filed: 2012-12-21
Abstract: The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.
Patent EA-029111-B1 (EA)
Title: Screw-adjustable connector apparatus for telescoped wear and support members
Inventor: CAMPOMANES PATRICK
IPC: E02F9/28
Filed: 2013-03-12
Abstract: The present invention relates to ground-engaging apparatuses such as that used in excavating and mining operations. According to the invention an earth engaging assembly comprises a support member (14), a wear member (12) telescoped with the support member (14) rearwardly along a first axis (A), the support member (14) and the wear member (12) having communicating connector openings (28, 30, 32) generally aligned along a second axis (A) transverse to the first axis, and a connector apparatus (10) disposed in said connector openings and releasably retaining the wear member (12) on the support member (14). The connector apparatus (10) comprises a spool member (16), a shim member (20) forwardly spaced apart from the spool member (16) and a wedge screw member (18) positioned between the spool member (16) and the shim member (20), the wedge screw member (18) being threadingly advanceable relative to the spool member (16) to rearwardly move the spool member (16) relative to the shim member (20) and thereby rearwardly move the wear member (12) relative to the support member (14), to tighten the fit therebetween loosening during operation. The invention also relates to the connector apparatus (10) for such earth engaging assembly.
Patent EA-029895-B1 (EA)
Title: Heterophasic polypropylene composition (variants), article and use of the composition
Inventor: TRANNINGER MICHAEL
IPC: C08L23/12
Filed: 2013-11-28
Abstract: Tiger stripe modifier being a heterophasic polypropylene composition with a melt flow rate MFR(230°C) in the range of 0.5 to 20 g/10 min and comprising a propylene homopolymer and an elastomeric propylene copolymer, wherein said propylene homopolymer has a melt flow rate MFR(230°C) in the range of above 10 to 300 g/10 min; the xylene cold soluble fraction of the heterophasic polypropylene composition has an intrinsic viscosity in the range of more than 2.5 to below 11.0 dl/g; and the comonomer content of the xylene cold soluble fraction of the heterophasic polypropylene composition is in the range of 10.0 to 25.0 wt.%; wherein further the heterophasic polypropylene composition fulfills the inequation (I)wherein C is the comonomer content in wt.% of the xylene cold soluble (XCS) fraction of the heterophasic polypropylene composition (HECO1), and IV is the intrinsic viscosity in dl/g of the xylene cold soluble (XCS) fraction of the heterophasic polypropylene composition (HECO1).
Patent EA-030421-B1 (EA)
Title: Anti-egfr antibodies and uses thereof
Inventor: DALY CHRISTOPHER
IPC: C07K16/28
Filed: 2013-06-25
Abstract: The present invention provides antibodies that bind to EGFR and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human EGFR with high affinity. In certain embodiments, the antibodies of the present invention are capable of inhibiting the growth of tumor cells expressing high levels of EGFR and/or inducing antibody-dependent cell-mediated cytotoxicity (ADCC) of such cells. The antibodies of the invention are useful for the treatment of various cancers as well as other EGFR-related disorders.
Patent EA-028037-B1 (EA)
Title: MONO-PHOSPHATE SALT OF 6-FLUORO-2-[4-(PYRIDIN-2-YL)BUT-3-YN-1-YL]IMIDAZO[1,2-a]PYRIDINE AND POLYMORPHS THEREOF AS NEGATIVE ALLOSTERIC MODULATOR OF mGluRECEPTOR
Inventor: BONNET BEATRICE
IPC: C07D471/04
Filed: 2014-09-25
Abstract: The present invention relates to crystalline and amorphous forms of 6-fluoro-2-[4-(pyridin-2-yl)but-3-yn-1-yl]imidazo[1,2-a]pyridine mono-phosphate salt and methods of making these solid forms thereof. The invention compounds are modulators of mGluwhich are useful for the treatment or prevention of central nervous system disorders as well as other disorders modulated by mGlureceptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGlu5 is involved.
Patent EA-035332-B1 (EA)
Title: Polypeptides targeting hiv fusion
Inventor: KRYSTAL MARK R
IPC: C07K14/78
Filed: 2016-04-14
Abstract: The invention is directed to polypeptides comprising a CD4 binding moiety, a gp41 binding moiety, a HIV fusion peptide inhibitor moiety and combinations thereof. More specifically, the present invention relates to polypeptides comprising a fibronectin-based scaffold domain protein that binds CD4, a fibronectin-based scaffold domain protein that binds the N17 domain of gp41, and a HIV fusion peptide inhibitor or combinations thereof. The invention also relates to the use of the innovative proteins in therapeutic applications to treat HIV.
Patent EA-037915-B1 (EA)
Title: Clinical formulations
Inventor: GAY ROGER
IPC: A61K47/26
Filed: 2016-08-18
Abstract: Some aspects of the invention provide clinical media that support viability, replating efficiency, and repopulation capacity of cells and tissues during storage for up to 48 h or longer. The clinical media provided herein are also useful for clinical irrigation. Cell or tissue preparations comprising a cell population or tissue and a clinical medium as provided herein are also provided, as are methods for generating such preparations. Methods for using the clinical media and cell and tissue preparations provided herein, for example, for administering an effective amount of cells or tissue to a subject in need thereof, are also disclosed.