baber/WOPTO huggingface dataset:
Patent EP-3277312-A2 (EP)
Title: Vaccins anticancéreux à base de microparticules de silicium poreux et procédés de potentialisation de l'immunité anti-tumorale
Inventor: SHEN HAIFA
IPC: A61K39/00
Filed: 2016-04-01
Abstract: L'invention concerne des microparticules de silicium poreux, qui sont à l'origine d'une avancée importante dans le domaine des agents d'immunothérapie anticancéreuse et de la nanomédecine moléculaire. En particulier, l'invention concerne de puissants adjuvants à base de microparticules de silicium poreux pour des compositions vaccinales à base de cellules dendritiques, et leurs procédés d'utilisation dans diverses immunothérapies anticancéreuses. Les microparticules de silicium poreux de la présente invention sont également utiles dans le développement d'autres types de vaccins, y compris des vaccins qui ne sont pas nécessairement liés au traitement de cancers, tels que des vaccins pour le traitement de l'acné, de la maladie d'Alzheimer, de l'asthme, de l'athérosclérose, des troubles auto-immuns, des maladies auto-inflammatoires, de la maladie cœliaque, de la colite, de la maladie de Crohn, du diabète, de la glomérulonéphrite, des maladies infectieuses, de la maladie intestinale inflammatoire, du syndrome du côlon irritable, de l'ischémie, du lupus, d'une maladie inflammatoire pelvienne, d'une lésion de reperfusion, de la polyarthrite rhumatoïde, de la sarcoïdose, du rejet de greffe et des maladies associées.
Patent EP-3286867-A2 (EP)
Title: Procédé, appareil et système d'injection de clé dans une machine de chiffrement en nuage
Inventor: FU YINGFANG
IPC: H04L9/08
Filed: 2016-04-19
Abstract: L'invention concerne un système d'injection de clé dans une machine de chiffrement en nuage comprenant au moins un sous-système d'injection de clé comportant un dispositif de génération de clé et un dispositif de distribution quantique de clé connecté au dispositif de génération de clé, et un sous-système hébergeant la machine de chiffrement en nuage comprenant une machine de chiffrement comportant un dispositif de chiffrement virtuel et un dispositif de distribution quantique de clé connecté à la machine de chiffrement. Le sous-système d'injection de clé et le sous-système hébergeant la machine de chiffrement en nuage sont connectés les uns aux autres par le biais de leurs dispositifs respectifs de distribution quantique de clé. Le dispositif de génération de clé peut générer une composante de clé racine du dispositif de chiffrement virtuel et transmettre cette composante de clé racine à la machine de chiffrement. La machine de chiffrement peut recevoir des composantes de clé racine à partir d'un ou plusieurs dispositifs de génération de clé et synthétiser une clé racine du dispositif de chiffrement virtuel en fonction des composantes de clé racine reçues.
Patent EP-3380082-A2 (EP)
Inventor: MITRAGOTRI SAMIR
IPC: A61K31/70
Filed: 2016-11-23
Abstract: La présente invention concerne des composés et des formulations pharmaceutiques contenant ces composés. L'invention porte en outre sur des procédés de production et d'utilisation de ces composés. Les composés incluent des nucléobases, des analogues de nucléobases, ou leurs combinaisons. Dans un mode de réalisation, un analogue de nucléobase est combiné à la doxorubicine et encapsulé dans un liposome pour inhiber ou empêcher la croissance de cellules cancéreuses. L'invention concerne en outre des compositions pharmaceutiques contenant au moins deux agents actifs au plan thérapeutique encapsulés dans une vésicule, telle qu'un liposome, le rapport molaire des agents fournissant un effet thérapeutique synergique.
Patent EP-3214670-A2 (EP)
Inventor: FRERS KLAUS DIETER
IPC: H01M10/613
Filed: 2016-04-15
Abstract: Ein Batteriemodul für eine Mehrzahl derartiger Batteriemodule (1) aufweisende Batterieanordnungen hat eine Batterieeinheit (2), die eine Vielzahl miteinander verbundener Batteriezellen (3) aufweist, eine Gehäusebaugruppe (12, 13, 14) mit einer Bodenplatte (12) und zwei einander gegenüberliegend angeordneten Seitenwandungen (13, 14), die vorzugsweise mittels Schraubverbindungen (19) mit der Bodenplatte (12) verbindbar sind und an ihren unteren Längskanten (15) auf ihrer Innenseite Längsvorsprünge (16) aufweisen, die in an zugeordneten Längskanten (17) der Bodenplatte (12) ausgebildete Längsausnehmungen (18) eingreifen, und einer Aufnahmeschale (20), die aus Kunststoff ausgebildet ist, auf der Innenseite der Bodenplatte (12) ruht und an ihren Längsseiten in aufwärtiger Richtung vorstehende Abkantungen (21, 22) ,  aufweist, zwischen denen ein unterer Abschnitt der Batterieeinheit (2) des Batteriemoduls (1) aufnehmbar ist, und eine Steuerbaugruppe (4, 5), die eine Steuerplatine (4) zur Überwachung und Regelung des Betriebs der Batterieeinheit (2) und einen Tragrahmen (5) aufweist, der auf der Batterieeinheit (2) lagert und an dem Zellverbinder angeordnet sind, mittels denen jeweils zwei Batteriezellen (3) der Batterieeinheit (2) untereinander verbindbar sind.
Patent EP-3206102-A2 (EP)
Inventor: ITO SHINGO
IPC: G05B23/02
Filed: 2017-01-26
Abstract: Provided is an event-combination assessment apparatus including: an event management table (5a) in which to store occurrence probabilities of at least basic events; a minimal-cut-set management table (5b) in which to store minimal cut sets each being a minimal combination of the basic events which possibly causes the top event; a processor (3) that identifies, based on each of the minimal cut sets stored in the minimal-cut-set management table (5b), event combinations each of which possibly causes the top event in combination with a single basic event, and calculates occurrence probabilities of the respective event combinations based on the occurrence probabilities of the basic events stored in the event management table (5a); and an event combination management table (5c) in which to store the event combinations identified by the processor (3) and the occurrence probabilities of the event combinations calculated by the processor (3). Thus, the event-combination assessment apparatus can assess the event combinations each of which possibly causes a top event in combination with a single event.
Patent EP-3200048-A2 (EP)
Inventor: TOMIYAMA TATSUHIRO
IPC: G06F3/01
Filed: 2017-01-30
Abstract: An image display apparatus (10) includes an image data processing unit (32) configured to generate image data for at least one information image, an image forming unit (40) configured to form the information image in a predetermined display area on an image forming plane based on the image data, an importance determination unit (33) configured to determine an importance of the information image, and a level control unit (34) configured to change an enhancement level of the information image based on a determination result of the importance determination unit.
Patent EP-3287865-A2 (EP)
Inventor: JIANG HAO
IPC: G02B27/01
Filed: 2017-03-02
Abstract: The present invention relates to virtual reality glasses, which include: a glasses body (1), which defines a first surface (11) towards a user's face and a second surface (12) configured to have an external electronic device (200) mounted thereon for playing virtual reality content; and a fastening structure configured to fasten the external electronic device (200) to the second surface (12). The fastening structure includes: a connector fastener (31) with a built-in connector (313) which is connectable to an interface at a first end of the external electronic device (200), wherein the connector fastener (31) enables the connector (313) to rotate between a predetermined maximum tilt opening angle (α) and a horizontal fastening angle, and the connector fastener (31) is configured to fasten the first end of the external electronic device (200) at the horizontal fastening angle; and at least one device fastener (32) which is configured to fasten a second end of the external electronic device (200).
Patent EP-3276596-A2 (EP)
Inventor: NAGAO KEI
IPC: G09G3/00
Filed: 2017-07-26
Abstract: A semiconductor device includes: a diagnosis portion which diagnoses, when the device is started up, whether an abnormality occurs in a component for setting that is externally connected; and a control portion which stops the startup of the device when the diagnosis portion diagnoses that an abnormality occurs, the diagnosis portion diagnoses whether an abnormality occurs in which the connection of the component for setting that is a resistor is disconnected, the semiconductor device further includes an external terminal which is connected to one end of the resistor and the diagnosis portion includes a constant current circuit which passes a constant current through the resistor via the external terminal, a comparator to which a voltage produced at the external terminal is input and a transistor which switches between the connection and interruption of a path along which the constant current is passed.
Patent EP-3287210-A2 (EP)
Inventor: BARTIG PAUL
IPC: B21J15/36
Filed: 2017-08-22
Abstract: Method for forming a joint in a stack of at least two sheets (18, 20, 22) of material using a self-piercing rivet (10), arrangement and self-piercing rivet (10) comprising a rivet head (12) and a rivet shank (14) with a central shank hole (16). The rivet head (12) has a top side (24), a bottom side (26) opposite the top side and a cylindrical head exterior surface (28) of a predetermined head diameter (Dh). The rivet shank (14) has an essentially cylindrical shank exterior surface (30) and a cylindrical shank interior surface (32). The bottom side (26) and the shank interior surface (32) limits the central shank hole (16). The rivet head has along the central axis (X) between the top side and the bottom side a predetermined thickness (th). The self-piercing rivet has a predetermined axial length (La) along the central axis, and the ratio between the predetermined thickness and the predetermined axial length ratio is between 1/7 and 1/22.
Patent EP-3474112-A2 (EP)
Title: Verfahren zum ermitteln einer erwarteten temperaturkurve sowie verfahren zum ermitteln eines heiz- und/oder kühlprogramms eines heiz- und/oder kühlsystems
Inventor: WITZEL MICHAEL
IPC: G05D23/19
Filed: 2018-10-08
Abstract: Die Erfindung betrifft ein Verfahren (10) zum Ermitteln einer erwarteten Temperaturkurve (12) beim Aufheizen oder Kühlen eines Raums durch ein Heiz- und/oder Kühlsystem (58) zum Erreichen einer vorgegebenen Soll-Temperatur (28) im Raum - wobei die erwartete Temperaturkurve (12) einen zukünftigen Zeitverlauf einer Ist-Temperatur des Raums vorhersagt. Das Verfahren umfasst die folgenden Schritte: 
¢ Ermitteln wenigstens eines Einflussfaktors, insbesondere einer Außentemperatur, 
¢ Ermitteln der erwarteten Temperaturkurve (12) in Abhängigkeit vom wenigstens einem Einflussfaktor, von der Soll-Temperatur und von historischen Temperaturdaten, wobei die erwartete Temperaturkurve ein Zeitintervall zum Erreichen der Soll-Temperatur (28) umfasst und die historischen Temperaturdaten durch früher abgespeicherte Temperaturkurven gebildet werden.  Die Erfindung betrifft auch ein Verfahren (36) zum Ermitteln eines Heiz- und/oder Kühlprogramms (32) eines Heiz- und/oder Kühlsystems zum Erreichen eines vorgegebenen Temperaturzeitverlaufs (38), ein Computerprogramm, welches dazu eingerichtet ist, alle Schritte eines Verfahrens (10, 36) gemäß der vorliegenden Erfindung auszuführen, ein maschinenlesbares Speichermedium, auf dem das Computerprogramm gemäß der vorliegenden Erfindung gespeichert ist, sowie ein Heiz- und/oder Kühlsystem (58) - insbesondere ein System zur Hausautomation - oder wenigstens eine Komponente (60, 62, 66) des Heiz- und/oder Kühlsystems (58), das bzw. die durch eine entsprechende integrierte Schaltung und/oder ein auf einem Speicher gespeichertes Computerprogramm gemäß der vorliegenden Erfindung dazu eingerichtet ist, ein Verfahren (10, 36) gemäß der vorliegenden Erfindung auszuführen.
Patent EP-3493174-A2 (EP)
Inventor: HYLAND GREGORY E
IPC: G08B25/00
Filed: 2009-10-27
Abstract: An infrastructure monitoring system and method that comprises multiple monitoring devices and/or multiple output devices. Each monitoring device includes at least one sensor for collecting data, a data storage device for storing the data, a processor for analyzing the data, and a communications device for transmitting and receiving data. The system may also include an operations center for controlling and receiving data from the plurality of devices.
Patent EP-3623075-A2 (EP)
Title: Verstelleinrichtung für die schmalseite einer stranggiesskokille, und verfahren zum verstellen einer schmalseite einer stranggiesskokille
Inventor: WEYER AXEL
IPC: B22D11/16
Filed: 2019-09-10
Abstract: Die Erfindung betrifft eine Verstelleinrichtung (10) und ein Verfahren zum Verstellen einer Schmalseite einer Stranggießkokille (12). Durch Ansteuerung eines Stellglieds (14), das mit einer Kokillen-Schmalseite (11) insbesondere durch ein Gelenk (16) verbunden ist, wird die Kokillen-Schmalseite (11) im Betrieb einer Stranggießanlage in Richtung einer Anstellachse (A) gemäß einer Sollposition angestellt. Temperaturänderungen (ΔT) an dem Stellglied (14) oder von Teilen davon werden mit zumindest einem Temperatursensor (20) gemessen und in thermisch bedingte Längenveränderung des Stellglieds (14) umgerechnet. Auf Grundlage dessen werden dann Korrekturwerte bestimmt, die zur Ansteuerung des Stellglieds (14) auf entsprechende Steuersignale aufgeschaltet werden, um dadurch auftretende Längenänderungen zu kompensieren.
Patent EP-3880819-A2 (EP)
Inventor: JASCHINSKI FRANK
IPC: A61K31/7088
Filed: 2019-11-13
Abstract: The present invention refers to an ANGPTL4 inhibitor consisting of an oligonucleotide comprising 12 to 22 nucleotides, wherein at least one of the nucleotides is modified, and the oligonucleotide hybridizes with a nucleic acid sequence of ANGPTL4 of SEQ ID NO.1 (human), ANGPTL4 of SEQ ID NO. 2 (human), ANGPTL4 of SEQ ID NO.58 (mouse) and/or ANGPTL4 of SEQ ID NO.59 (mouse), wherein the oligonucleotide inhibits the expression of ANGPTL4, and a pharmaceutical composition comprising such inhibitor and a pharmaceutically acceptable carrier, excipient, dilutant or a combination thereof.
Patent EP-3877761-A2 (EP)
Inventor: Greenawalt Angella Nicholle
IPC: G01N31/22
Filed: 2019-11-05
Abstract: An embodiment provides a method for measuring a concentration of lead(O) in an aqueous sample, including: introducing an aqueous sample to a reaction vessel; adding a copper(II) acetate material to the aqueous sample in the reaction vessel; chelating unreacted copper(II) material by introduction of an organosulfur compound to the aqueous sample in the reaction vessel; adding a colorimetric indicator to the aqueous sample in the reaction vessel; and measuring a concentration of lead(II) in the aqueous sample by measuring a colorimetric change of the aqueous sample caused by a reaction of lead(II) within the aqueous sample with the colorimetric indicator. Other aspects are described and claimed.
Patent EP-3880719-A2 (EP)
Inventor: GOLDBACH JAMES T
IPC: C08F2/26
Filed: 2019-11-06
Abstract: The invention relates to a process to produce a stable fluoropolymer latex using non-fluorinated surfactant with greater thermal stability. The polymerization is run at pressures greater than typically used. The resulting polymer exhibit improved melt color stability as compared to those produced under similar conditions at lower pressures.
Patent EP-3662949-A2 (EP)
Inventor: AZZOPARDI ANNA
IPC: A24F40/65
Filed: 2016-12-09
Abstract: A method of visualisation between an electronic vapour provision system and a visualisation device comprises the steps of obtaining from the electronic vapour provision system notification that an inhalation on the electronic vapour provision system by a user has occurred, estimating a time of exhalation by the user responsive to the time of notification, and initiating a display of a computer graphic by the visualisation device responsive to the estimated time of exhalation.
Patent EP-3721917-A2 (EP)
Title: Vacuum driven suction and irrigation system
Inventor: HEJMOWSKI TOMASZ
IPC: A61M1/00
Filed: 2020-04-08
Abstract: A vacuum assisted suction and irrigation system includes a suction and irrigation wand, an irrigation fluid supply, a vacuum source, and a dual impeller fluid pump. The vacuum source is connected to a suction valve of the suction and irrigation wand to provide suction within the suction and irrigation wand. The irrigation fluid supply is connected to the suction and irrigation wand via the dual impeller fluid pump to supply pressurized irrigation fluid to the suction and irrigation wand. The vacuum source is connected to the fluid pump to pressurize the irrigation fluid being delivered to the suction and irrigation wand.
Patent EP-3799943-A2 (EP)
Title: Truncated filter capsule
Inventor: LIN ZHENWU
IPC: B01D35/04
Filed: 2016-10-12
Abstract: The present invention relates to filter capsules for showers and sinks used in surgical settings, clean rooms and other contaminant-sensitive settings having modified outlets for improved splash control.An inlet that extends upwardly from a cap of the filter capsule has axis offset from the longitudinal axis of the capsule, wherein the capsule orientation permits directional control of the fluid path for fluids exiting the capsule/cartridge and rotation of the capsule about the inlet connection point rotates the fluid about a circular path.A filter capsule comprises: a capsule wall, a filter cartridge, a capsule top cap having an inlet with an axis offset from a filter capsule longitudinal axis, and a recessed outlet having a recessed outlet wall extending inwardly into a filter cartridge core.
Patent EP-3825689-A2 (EP)
Inventor: LEE CHEE GUN
IPC: G01N33/50
Filed: 2019-01-10
Abstract: The present invention relates to a cell and an antibody for determining the activity of botulinum toxin, and a method of determining the activity of botulinum toxin using the same. Currently, there is a need to develop a cell-based potency assay (CBPA) for replacing the mouse LD50 bioassay (mLD50) in the field of measurement of botulinum toxin potency. The cell and antibody for measuring the activity of botulinum toxin according to the present invention are a cell and an antibody for CPBA, which are to replace the mLD50. The cell line has a significantly short doubling time compared to conventional SiMa cells which are used to determine the activity of botulinum toxin, and also has significantly high sensitivity to botulinum toxin compared to its parental cell line. Thus, the cell line is very suitable not only for cell-based determination of the activity of botulinum toxin, but also for cell-based detection of botulinum toxin. Furthermore, the cell line according to the present invention can be attached to and cultured stably in a culture dish coated with poly-d-lysine (PDL), and thus can be very effectively used for cell-based determination of the activity of botulinum toxin or for cell-based detection of botulinum toxin. Moreover, the antibody is a monoclonal antibody having a significantly high binding affinity and specificity for SNAP25, overcomes the limitations of conventional CPBA, and makes it possible to develop a more effective CBPA. Thus, the antibody is expected to be actively used in the pharmaceutical and cosmetic fields. In addition, the present invention relates to an optimal cell-based potency assay (CBPA) which uses N2-42F cells and a monoclonal antibody having a significantly high binding affinity and specificity for SNAP25, and this CBPA can measure the potency of 0.5 U or less of botulinum toxin. The CBPA employing the cell and antibody of the present invention is expected to become a highly reliable and reproducible cell-based potency assay for botulinum toxin.
Patent EP-3938091-A2 (EP)
Inventor: BRULÉ AURÉLIEN
IPC: B08B15/02
Filed: 2020-03-09
Abstract: Machine (1) for distributing a product stored in a container (30) comprising a storage zone (2) delimiting locations (4) for housing a container (30), a metering station (5) delimiting a chamber (6) housing a support (7) for accepting a collecting vessel (33), this support (7) being positioned vertically in line with an opening (8) providing access to the chamber (6), which opening is arranged in an upper part (61) of the chamber (6), the machine (1) further comprising a system (10) for emptying each location (4) for housing a container (30) through the opening (8) providing access to the chamber (6), and a unit (14) for controlling the machine (1). The metering station (5) comprises a sensor (13) for detecting the presence of a collecting vessel (33) inside said chamber (6). The control unit (14) is configured to operate the machine (1) on the basis of data supplied by said sensor (13), and the metering station (5) is equipped with a circuit (15) for the circulation of gaseous fluid providing communication between the chamber (6) and the outside of said chamber (6) through a forced circulation of air.
Patent EP-3805392-A2 (EP)
Title: Nucleic acid sequence expressing sars-cov-2 virus antigen peptide and use thereof
Inventor: CHEN LING
IPC: A61P31/20
Filed: 2020-08-19
Abstract: The present disclosure discloses nucleotide sequences as shown by SEQ ID NO: 1, SEQ ID NO: 2 and the nucleotide sequences having at least 90% homology therewith, which encode peptide antigens of SARS-CoV-2 virus. According to some embodiments of the present disclosure, the nucleotide sequences can be effectively expressed in human cells and produce the corresponding peptides, thereby inducing an immune-protective response accordingly. Thus, the nucleotide sequences of the present disclosure are expected to be developed as a vaccine against SARS-CoV-2 infection.
Patent EP-3971299-A2 (EP)
Inventor: KOZONO SATOKO
IPC: C12N15/09
Filed: 2015-06-12
Abstract: It is intended to provide a kit or a device for the detection of colorectal cancer and a method for detecting colorectal cancer. The present invention provides a kit or a device for the detection of colorectal cancer, comprising a nucleic acid capable of specifically binding to a miRNA in a sample from a subject, and a method for detecting colorectal cancer, comprising measuring the miRNA  in vitro.
Patent EP-3954912-A2 (EP)
Inventor: REED BRAYTON
IPC: B64F5/40
Filed: 2019-11-20
Abstract: A method of repairing a composite material tube includes the steps of (a) identifying a damaged area on a composite tube, and (b) placing a patch on a surface of the tube and over the damaged area. A drive shaft (20) has a central tubular portion (30, 42) formed of a polymer composite with imbedded fibers. It extends between a first end and a second end. The central tubular portion has an outer peripheral surface. There is at least one ring (32,44)on the outer peripheral surface of the central tubular portion.
Patent EP-4185883-A2 (EP)
Inventor: SCHWARTZ ILAI
IPC: G01R33/30
Filed: 2021-07-23
Abstract: La présente invention concerne des systèmes et des procédés pour la génération de composés cibles hyperpolarisés. La génération d'un composé cible hyperpolarisé peut comprendre l'application d'une séquence d'impulsions micro-ondes à une solution contenant le composé cible ou un précurseur du composé cible ; ou la modulation d'un champ magnétique appliqué à la solution. Lorsque le précurseur est hyperpolarisé, le précurseur peut être clivé pour générer le composé cible hyperpolarisé. Le composé cible hyperpolarisé peut ensuite être amené à former un précipité dans la solution. Le précipité peut être redissous dans un volume spécifié de solvant pour former une solution ayant une concentration souhaitée du composé cible hyperpolarisé.
Patent EP-4251178-A2 (EP)
Inventor: CRAIGO JODI
IPC: A61K35/17
Filed: 2021-11-30
Abstract: L'invention concerne des compositions, des méthodes et des kits qui peuvent être utilisés pour traiter le cancer. Par exemple, des compositions pharmaceutiques contenant du béraprost ou des sels correspondants peuvent être utilisées en tant que thérapie adjuvante avec des lymphocytes T à récepteurs d'antigènes chimériques (cellules CAR-T) pour traiter le cancer tout en réduisant ou en éliminant Les effets indésirables et potentiellement dangereux du syndrome de libération des cytokines (CRS).