Patent SG-11201801756W-A (SG)
Title: Novel peptides and combination of peptides for use in immunotherapy against various cancers
Inventor: MAHR ANDREA
IPC: C07K7/08
Filed: 2016-12-05
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -' Organization International Bureau res., 00) (43) International Publication Date ..... ..sr ,„,„.1 15 June 2017(15.06.2017) WIPO I PCT ID Hit (10) WO 111111111111111111IIIIIIII International II 2017/097699 III IIIIIIIIIIIIIII Publication IIIIIIIIIIIIII Al Number RIO IIII IIIIIIII (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every CO7K 7/06 (2006.01) A61K 38/04 (2006.01) kind of national protection available): AE, AG, AL, AM, CO7K 7/08 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, (21) International Application Number: DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, PCT/EP2016/079737 HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, (22) International Filing Date: KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, 5 December 2016 (05.12.2016) MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (25) Filing Language: English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, (26) Publication Language: English TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: 1521894.4 11 December 2015 (11.12.2015) GB (84) Designated States (unless otherwise indicated, for every 62/266,233 11 December 2015 (11.12.2015) US kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, (71) Applicant: IMMATICS BIOTECHNOLOGIES GMBH TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, [DE/DE]; Paul-Ehrlich-Strasse 15, 72076 Tuebingen (DE). TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, (72) Inventors: MAHR, Andrea; Kirschenweg 22, 72076 DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, Tubingen (DE). WEINSCHENK, Toni; Im Morgenrain LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, 15, 73773 Aichwald (DE). SONG, Colette; Wil- li-Baumeister-Weg 21, 73760 Ostfildern (DE). SCHOOR, GW, KM, ML, MR, NE, SN, TD, TG). Oliver; Eichhaldenstrasse 19, 72074 Tilbingen (DE). Published: FRITSCHE, Larchenweg 11, Dussligen Jens; 72144 21(3)) with international search report (Art SINGH, Harpreet; 2215 Dryden Rd, Houston, (DE). Texas 77030 (US). — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of (74) Agent: BOEHMERT & BOEHMERT; KRAUSS Jan B., amendments (Rule 48.2(h)) Pettenkoferstrasse 20 - 22, 80336 Munich (DE). — with sequence listing of description (Rule 5.2(a)) part Il .4t Cr \ Cr \ !h . ' 0 \ (54) Title: NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST VARIOUS O CANCERS Ir --- (57) : The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In Il c:::, particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associ - el ated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active phar- 0 maceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.