baber/WOPTO huggingface dataset:
Patent JP-2724493-B2 (JP)
IPC: A61K31/4035
Filed: 1989-02-23
Granted: 1998-03-09
Abstract: The present invention relates to :   1) a method for the total synthesis of an indole structure derivative product class,of the triptamine type, in particular of the melatonine or N-Acetyl-5-Methoxy-triptamine type; 2) the use of melatonine or N-acetyl-5-methoxytriptamine as a drug with doses from 2 mg to 20 mg per day,in an oral,intramuscolar or endovenous way; 3) the use of melatonine or N-acetyl-5-methoxytriptamine, in combination with an azidothymidine treating process, in order to improve the curative effects.   The subject total synthesis process consists of combining potassium phthalamide and di-bromopropane in order to obtain 3-bromopropylphthalamide;adding, in the presence of ethanol dissolved sodium,acetacetic esther in order to obtain ethyl-2-acetyl-5-phthalimido-penta noate ;adding diazo-p-anisidine so as to obtain 2-carboxyethyl-3-(2-phthalimidoethyl)-5-methoxy-indole. The main feature of the invention is that to the 2-carboxyethyl-3-(2-phthalimidoethyl)-5-methoxy-indole there are added NaOH 2N and 20% H2SO4 in order to obtain raw 5-methoxytriptamine;which is purified by means of hexamethyldisilazane,with the formation of the related mono and bi-derivative therefrom there is obtained the starting product which is purified by means of aqueous methanol. The subject method,in particular,is specifically designed for provided high purity melatonine,or N-acetyl-5-methoxytriptamine,with a great yield,which is water soluble and may be used for therapeutic purposes. The thus obtained melatonine,has such a purity that it can be used,in suitable packages,both in tumoral phrophilaxy and tumoral terapy,as well as against the acquired immuno-deficiency syndromes,o so called AIDS.
Patent JP-3293933-B2 (JP)
IPC: B21B1/18
Filed: 1993-03-05
Granted: 2002-06-17
Abstract: The invention relates to a method for rolling wire or stock having a circular cross-section made of special steel or some other alloy steel in a high-duty small-section/wire rod train. In order to be able to achieve the narrowest possible wire tolerances, it is proposed to roll the stock 5 in the rerolling block 6 of the train with a significantly smaller pass reduction than the reduction passes carried out in the finishing block 1 of the wire rod train. The wire rod train consists of a roughing train having in each case a plurality of roll stands or rolling units, at least one intermediate train and a subsequent finishing train, and the latter is, in particular, designed as a finishing block. Arranged on the output side of the finishing block is an at least two-stand rerolling block 6 and arranged between the finishing block and the rerolling block there is, if required, a cooling section 13 and/or a temperature equalising device 14. In order to be able to use the rerolling block as a precision rolling block, it is fitted with a change gear 15 for changing it into a temper (skin pass) or precision rolling stand. <IMAGE>
Patent JP-3252868-B2 (JP)
IPC: H01G11/86
Filed: 1993-02-10
Granted: 2002-02-04
Abstract: PURPOSE:To allow the carbon particles of electrode material to penetrate into the interior of the meshes of a metal porous body of three dimensional reticular structure which is formed by conducting electroplating on foamed resin which is used as a current collecting body and the foamed resin is used for the metal porous body, having three-dimensional structure, which is formed by burning off the foamed resin by heat treatment. CONSTITUTION:A conduction treatment is performed on urethane foam by carbon coating and the like, and nickel or nickel-chrome is electroplated thereon, for example. Then, the foamed resin is burnt out, and a porous metal body, having three-dimensional reticular structure, is obtained. A cellumet, having porosity rate of 98% and the density of 0.18gr/sq cm, is used as a current collecting body 2. Also, activated carbon of surface area of 1700sqmm/g and carbon powder are mixed at the ratio of 5:5, paste-like material is obtained by adding a binder, and it is used as an electrode material 3. The current collecting body 2 is coated with the electrode material 3 uniformly, dried up, rolled out, and a carbon electrode 1 of uniform thickness is obtained. A read terminal is attached to the carbon electrode 1, an electrolyte is impregnated, and current collecting efficiency is greatly improved.
Patent JP-H0535542-B2 (JP)
IPC: H01J9/12
Filed: 1985-03-11
Abstract: A method for producing a multichannel plate containing metal dynodes and having a plurality of generally parallel channels for use in structures for amplifying or converting optical images or other two-dimensional signal patterns by secondary electron multiplication, which method includes: producing a negative mold of the plate by: (i) providing a body having at least the thickness of the plate to be produced and made of an electrically insulating material whose ability to be removed from the body is altered by exposure to a selected radiation; (ii) irradiating the body with the selected radiation in a pattern corresponding to the plate to be produced and in a manner to render portions of the body having the form of a grid surrounding the channels more easily removable than the remaining portions of the body; and (iii) removing the more easily removable portions of the body to leave columnar structures corresponding to the channels in the plate; depositing metal layers and intermediate layers alternatingly in the openings in the negative mold or in a secondary negative mold produced therefrom, the metal layers being deposited electrolytically and forming dynodes which are spaced apart in the direction of the channels; and removing the negative mold from the deposited layers.
Patent JP-S6129519-B2 (JP)
IPC: G10L15/32
Filed: 1978-05-06
Abstract: PURPOSE:To increase a processing speed by extracting a sampling point which corresponds to a vowel part in a monosyllable, by selecting a recognition-expectant monosyllable, through the collation with the previously-registered reference vowel feature quantity, and by collating the monosyllable with an unknown voice. CONSTITUTION:By making use of the steadiness of the extracted feature quantity, steady-vowel-part extraction circuit 6 extracts a sampling point which corresponds to a vowel part in a monosyllable and then collates 10 a vowel feature quantity, which corresponds to this sampling point, with the reference vowel feature quantity previously registered for each monosyllable. As a result, the recognition-expectant monosyllable is determined and then collated 13 again with an unknown voice. Consequently, the processing speed can be increased.
Patent JP-H0368925-B2 (JP)
IPC: C21C5/32
Filed: 1983-04-22
Abstract: For improving permeability of a metallurgical vessel bottom provided with permeable refractory elements for controlled injection of a stirring fluid into a molten metal bath, the metallurgical vessel is emptied of its contents, a castable composed of a refractory material compatible with the refractory material of the bottom is deposited in the bottom and spread over the latter, and the castable is left to dry and set, while maintaining in the permeable refractory elements a sufficient pressure to provide a permanent flow of a stirring fluid. A hydraulic magnesian refractory castable used in this method has a content of water of substantially between 8 and 10% by weight.
Patent JP-2714605-B2 (JP)
IPC: H01M50/491
Filed: 1996-03-27
Granted: 1998-02-16
Abstract: A multiply sheet product useful as a battery separator having at least two plies each in the form of a microporous sheet of predetermined length and breath and a thickness of less than 10 mils wherein (a) at least one of said ply being a sheet capable of transforming to a substantially non-porous membrane at a temperature between about 80°C and 150°C while essentially maintaining its length and breath dimensions and (b) at least one ply being a sheet capable of maintaining its dimensions and porosity at temperatures from ambient to at least about 10°C greater than the transformation temperature of sheet (a).
Patent EP-1187918-B2 (EP)
Inventor: CERRETTI DOUGLAS P
IPC: C07K16/28
Filed: 2000-06-07
Granted: 2009-01-14
Abstract: The present invention provides Tek antagonists and methods of inhibiting angiogenesis in a mammal by administering Tek antagonists. The methods are particularly useful in treating diseases or conditions mediated by angiogenesis, such as solid tumors and diseases or conditions characterized by ocular neovascularization.
Patent EP-0080830-B2 (EP)
IPC: B65H29/40
Filed: 1982-11-18
Granted: 1990-06-20
Abstract: Paper leaves, conveyed through a conveyer belt system, are inserted into arcuate grooves of rotating conveying wheels and subjected to a running speed reduction, and discharged under the rotating conveying wheels into a space by the use of a stopper. When the number of paper leaves falling into the space reaches a preset count, for example, projecting devices are actuated to project bar elements into the space, with paper leaves exceeding the preset count being piled on the bar elements. The preset number of paper leaves are then transferred from the space. Once transfer is complete, the bar elements are retracted enabling the paper leaves collected thereupon to fall into the space.
Patent EP-0156170-B2 (EP)
Inventor: BRAND JULIA A
IPC: C08F2/02
Filed: 1985-02-25
Granted: 1996-06-05
Abstract: A process to continuously bulk polymerize acrylic monomers to prepare low molecular weight, uniform, polymers employs minor amounts of initiator and, optionally solvents, at short residence times and moderate reaction temperatures to provide high yields of a product suitable for high solids applications.
Patent EP-0395329-B2 (EP)
Inventor: HEALEY JOHN NORMAN CHARLES
IPC: A61K9/00
Filed: 1990-04-23
Granted: 1999-11-17
Abstract: Pharmaceutical compositions suitable for intra-rectal administration in the form of a foam are described which comprise a therapeutically effective amount of 5-aminosalicylic acid, a pharmaceutically acceptable aqueous carrier therefor, and means for generating a foam. Methods for their preparation and their use in the treatment of ulcerative colitis are also described.
Patent EP-0466914-B2 (EP)
Title: Immunochromatographic  method
Inventor: FAN EUGENE
IPC: G01N33/558
Filed: 1991-02-08
Granted: 2007-06-06
Abstract: The invention disclosed herein relates to the field of one-step assays and latex agglutination tests ("LAT"), and provides an improved method of preparing and using a one-step immunoassay, as well as improved methods of preparing coated latex particles for use in diagnostic assays, and especially, immunochromatographic assays.
Patent EP-0520738-B2 (EP)
Inventor: STERN SIDNEY S
IPC: F25J3/08
Filed: 1992-06-23
Granted: 1999-03-17
Abstract: Air is rectified in a rectification column 24 to produce at its top a gaseous nitrogen fraction relatively to produce a rich in light elements, such as neon, helium and hydrogen. A stream of this gaseous fraction is then partially condensed within a condenser 32 and separated into liquid and vapour phase within a phase separator 48. The liquid phase is lean in the light elements and the vapour phase is rich in the light elements. The liquid phase is removed from the bottom of the phase separator 48 and is introduced into the column 24 as reflux. As the reflux descends from tray to tray it is stripped of light elements. A product stream containing ultra-high purity nitrogen is withdrawn as a liquid stream 62 from the column 24 after suitable stripping of the reflux. The product stream 62 can be further purified by stripping within a stripper column 68. <IMAGE>
Patent JP-S6030960-B2 (JP)
IPC: G10L13/07
Filed: 1977-09-13
Abstract: A speech signal synthesizer features a time and frequency scaler for improved accuracy of signal synthesis. A digital signal representative of a first analog signal, such as a voice signal, having varying parameters, such as frequenty or amplitude, is converted by a synthesizer into an analog output signal which varies in substantially the same manner as the first signal. The synthesizer receives a transmitted digital signal representing the first analog signal and synthesizes the varying parameters thereof to provide the analog output signal. First, the digital input signal is applied to a serial-to-parallel converter and subsequently input to a modulated frequency generator controlled by the operation of a modulation controller. Digital data processed through the modulated frequency generator is time and frequency scaled, and it is this time and frequency scaling that provides improved accuracy in recreating the proper amplitude relationship of the first analog signal. Following time and frequency scaling, the processed digital data is input to an amplitude accumulator and subsequently converted into the analog output signal in a digital-to-analog converter. Time scaling is implemented by apparatus that utilizes the transmitted digital data information to interpolate between spectrum segments to present a smooth spectrum to the output analog signal. For frequency scaling, the frequency scaler interpolates between harmonic frequencies of the first analog signal in consecutive frames and the processed digital data of the time scaling. Both the time domain scaling and the frequency domain scaling are based on the value of a cosine squared function extending between adjacent data points on adjacent frames.
Patent JP-S6249269-B2 (JP)
IPC: A01N43/40
Filed: 1983-06-18
Abstract: Certain novel pyridinyloxyphenoxy alkanoic acids, pyridinylthiophenoxy alkanoic acids, derivatives thereof and related compounds are described. More specifically, these novel compounds bear a fluorine substituent in the 3-position of the pyridinyl group and in the 5-position the substituent is selected from chlorine, CF3, CF2Cl or CF2H. These novel compounds exhibit surprising preemergent and postemergent activity in the control of grassy weeds.
Patent JP-3119831-B2 (JP)
IPC: A61F2/06
Filed: 1997-04-30
Granted: 2000-12-25
Abstract: A prothesis (18, 108, 120) for transluminal implantation consists of a flexible tubular three-dimensionally braided structure of metal or polymeric monofilaments (32, 110, 126), and polymeric multifilament yarns (42). The prosthesis can be elastically deformed to reduce its diameter through axial elongation. The monofilaments and multifilament yarns are arranged in axially spaced apart helices, concentric on a common central axis of the prosthesis. The monofilaments are selectively shaped before their interbraiding with the multifilament yarns, either by an age-hardening or other heat-setting stage, or a cold-working stage that controllably plastically deforms the strands. The shaped structural strands cooperate to impart to the prosthesis its nominal shape and resilience. The textile strands cooperate to provide one or more layers of sheeting (40) that reduce permeability and thereby enhance the utility of the prosthesis as a vascular graft. An alternative embodiment prosthesis (132) includes elastically and plastically deformable structural strands (140), selectively plastically deformed by cold working, then three-dimensionally braided to form the prosthesis. <IMAGE>
Patent JP-2960434-B2 (JP)
IPC: G11B7/24
Filed: 1989-05-06
Granted: 1999-10-06
Abstract: The disclosure relates to a thin film structure having magnetic and optical variable properties comprising a substrate (12) and a multilayer interference coating (16) carried by the substrate producing an inherent colour shift with angle. The interference coating has a metal-dielectric design which includes a metal (17) which has reflective as well as magnetic properties.
Patent JP-H0353364-B2 (JP)
IPC: C21C5/34
Filed: 1983-06-29
Abstract: In the process for making steel from scrap, in each converter cycle following the charging of scrap, an amount of hot metal charge originating from a preceding converter cycle is charged over the scrap. The total charge is melted down through the introduction of fuel and oxygen via sub bath or submerged inlet tuyeres. The molten tap is tapped either into two storage vessels, in repetition cycles, and used as a hot metal charge during two subsequent charges, or the tap is added for subsequent processing, in production cycles, particularly for a casting operation wherein finish-refining is effected prior to the tapping.
Patent JP-3689529-B2 (JP)
IPC: G02F1/1333
Filed: 1997-05-12
Granted: 2005-08-31
Abstract: PROBLEM TO BE SOLVED: To fill resin equally and with good flatness between metallic wires by removing the squeeze-out of resin. SOLUTION: A wiring board 15 is manufactured by forming a band-shaped projection 10 around the position 5mm or more apart from the outermost metallic wiring, and pressing the UV hardening resin injected between a glass substrate 6 and a mold board thereby spreading the UV hardening resin 7, and then, hardening it. Hereby, the squeeze-out of the UV hardening resin 7 from the edge of the glass board 6 is suppressed by the band-shaped projection 10 at the time of pressing, whereby the shortage region of the UV hardening resin 7 on the glass board 6 vanishes, and the UV hardening resin 7 is filled equally and besides with good flatness between the metallic wires.
Patent JP-3261542-B2 (JP)
IPC: B65D83/76
Filed: 1992-04-17
Granted: 2002-03-04
Abstract: The device comprises a container (2) provided in its upper part with a distributor head (4) offset towards the front with respect to the axis (A) of the container, which can be actuated by depression and which can rotate about an axis (B) parallel to its direction of depression, and a cap (12) provided with an actuating lever (14) hinged on to the front and having a support (P) for acting on the head (4) when a user applies pressure to the rear part of the lever. The cap (2) has an opening (26) for the passage of the sprayed product. Guide elements are provided between the cap (12) and the container (2) so that the cap is mounted in a predetermined angular direction in such a manner that the opening (26) is situated at right angles with the outlet (8) of the distributor head (4), and the support (P) can act on the head (4) when the various elements have been assembled in the correct angular position.
Patent JP-H026363-B2 (JP)
IPC: F16D65/22
Filed: 1982-07-19
Abstract: PURPOSE:To make a device small-sized and also improve the brake force and operability by connecting a manual handle and disks so that two disks are rotated simultaneously in opposite directions to pinch friction pins. CONSTITUTION:When a handle shaft 4 is rotated clockwise as seen from above, disks 6, 7 are rotated in opposite directions by means of an arm 16, friction pins 81, 82 of individual disks are rotated in opposite directions, a cam 12 and a ring 13 pinch the pins 8, thus a brake force is generated by friction. The friction pins provided on individual disks are restricted in their moving ranges by the through holes provided on the opposite disks, and protrude between the cam 12 and ring 13.
Patent JP-H0569762-B2 (JP)
Inventor: JUNUIEEU RANIERU
IPC: C01B15/037
Filed: 1989-06-09
Abstract: Liquid composition for stabilising H2O2 in akaline medium which contains, per litre and in addition to water, 100 g to 300 g of potassium carbonate K2CO3 and 0 to 200 g of sodium carbonate Na2CO3 so as to make the sum of the quantities of K2CO3 and of Na2CO3 be 280 g to 300 g, 50 to 150 g of alkali metal hexametaphosphate and a quantity of an alkali metal salt of diethylenetriaminepentamethylenephosphonic acid such as to make the quantity of active diethylenetriaminepentamethylenephosphonic acid be between 15 g and 50 g.
Patent JP-H0721121-B2 (JP)
IPC: D21H21/30
Filed: 1985-08-22
Abstract: Methine-azo compounds of the formula   <IMAGE>   in which A is the complement to a heterocyclic 5- or 6-membered ring which has a quaternized N atom as a ring member, which can contain further hetero atoms and which can be substituted and/or fused with carbocyclic or heterocyclic rings, R is hydrogen, cyano or C2-C3-alkylene which is bonded to an N atom of ring A to form a 5- or 6-membered ring, B is substituted or unsubstituted phenylene or naphthylene, X(-) is an anion and KK is the radical of a coupling component of the benzene series, of the naphthaline series or of the heterocyclic series, with the provisos that (a) if A is the complement to a quaternized, substituted or unsubstituted pyridine, quinoline or indolenine radical, KK is not the radical of a substituted or unsubstituted phenol, sulfo-free naphthol, naphthylamine, aniline, quinoline, isoquinoline, pyrazole or indole coupling component and (b) if A is the complement to a quaternized, substituted or unsubstituted benzothiazole or pyrimidine radical, KK is not a substituted or unsubstituted phenol or aniline coupling component. These compounds can be used as dyes for dyeing or printing for example polyacrylonitrile, acid-modified polyester and in particular paper.
Patent JP-2509304-B2 (JP)
IPC: B65H29/40
Filed: 1988-07-28
Granted: 1996-06-19
Abstract: The invention relates to a device for collecting and depositing signatures which, arriving processed by rollers and transversely cut from a web, can be pulled apart by means of an acceleration device, can be offset laterally with respect to one another, in each case between the leading and trailing edge, by means of a deflection device which can be actuated in the signature cycle, can be collected in receiving compartments formed from vanes of a vane wheel driven in the collecting cycle and can be pushed out from said compartments onto a delivery conveyor, the signature cycle being an integral multiple of the collecting cycle. In order to design a device of the above type in such a way that the book blocks are precisely aligned at a high work speed, and with a particularly compact structure of the overall device, the invention is characterised in that the vanes are mounted so as to be pivotable axially parallel to the vane wheel axis on a hub of the vane wheel, in that, with uniform movement of the hub, the pivoting of the vane to be loaded can be controlled periodically in the collecting cycle with a phase of rapid movement into the initial receiving position, with a phase of slow movement in the angular collecting region, and with a phase of rapid movement out of the end receiving position, and in that the receiving compartment is formed by the vane and a leaf or wire spring connected to the rear of said vane. 
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Patent JP-3115910-B2 (JP)
IPC: B26B21/22
Filed: 1991-08-05
Granted: 2000-12-11
Abstract: An integrally formed flexible razor head (10) having a plurality of blade platforms (70) separated by a corrugation (60), at least one blade (20 or 30) having a cutting edge (21 or 31), and a plurality of blade retainers (40) which are integrally formed with the blade platforms (70) and extend to positions above and adjacent to the top surface of the blade (20,30). While the blade retainers (40) are integrally formed with the other pieces of the flexible razor head (10), each blade retainer (40) is discrete with respect to other blade retainers (40). <IMAGE>
Patent JP-H0777611-B2 (JP)
IPC: B01J23/86
Filed: 1986-08-29
Abstract: A catalyst suitable for use in catalytic shift, or methanol synthesis, comprises copper, zinc oxide, magnesia, and at least one trivalent metal oxide, e.g. alumina. The amount of magnesia is such that the magnesium atoms constitute 0.2 to 7% of the total number of copper, zinc, and magnesium atoms.