baber/WOPTO huggingface dataset:
Patent HU-181219-B (HU)
Inventor: KUGYELA ATTILA
IPC: G07G1/06
Filed: 1980-11-21
Abstract: Papierstreifenfoerderer fuer einen Zeilendrucker, vorzugsweise fuer elektronische Registrierkassen, bei welchem zur wahlweisen Durchfuehrung eines Zweizeilen- oder Einzeilenvorschubes das um eine Vorschubwalze 13 laufenden Papierstreifens ein Zahnsegmentrad 1 mit zwei Zahnsegmente a, b vorgesehen ist, von denen das eine Zahnsegment b unmittelbar mit dem Antriebszahnrad 2 der Vorschubwalze und das andere Zahnsegment a mit einem mit den Antriebszahnrad 2 kaemmenden Umkehrrad 4 zusammenwirken, das wahlweise in den Eingriffsweg des ihm zugeordneten Zahnsegmentes gehalten oder aus diesen Eingriffsweg wegbewegbar ist. Im ersteren Fall wird waehrend jedes Umlaufs des Zahnsegmentrades 1 der Papierstreifen 17 durch den Antrieb des Zahnsegmentes a und des Umkehrrades 4 um einen Zeilenabstand zurueckbewegt und danach durch den Antrieb des Zahnsegmentes b um zwei Zeilenabstaende vorbewegt. Im Ergebnis um einen Zeilenabstand vorgeschoben. Im letzteren Fall entfaellt die Rueckzugsbewegung des Papierstreifens 17 um einen Zeilenabstand und es erfolgt eine Vorschubbewegung um zwei Zeilenabstaende. Fig. 1 bis 3
Patent HU-208140-B (HU)
Title: Process for producing 3-exomethylene-cefam-sulfoxide ester derivatives
Inventor: COPP JAMES DENSMORE
IPC: C07D501/14
Filed: 1990-05-16
Abstract: 3-Exomethylenecepham sulfoxide esters are obtained in improved yields via cyclization of 3-methyl-2-(4-chlorosulfinyl-2-oxo-3-acylamino-1-azetidinyl)-3-butenoic acid esters under anhydrous conditions with stannic chloride in the presence of both an oxo compound, e.g., an ether such as diethyl ether, a ketone such as acetone or methylethyl ketone, and an unsaturated compound, e.g., an alkene such as 1- or 2-hexene, a non-conjugated alkadiene such as 1,4-hexadiene, a cycloalkene such as cyclohexene, an allene, or a non-conjugated cycloalkadiene such as 1,4-cyclohexadiene.
Patent HU-185746-B (HU)
Title: Logic toy of several toy levels
Inventor: JODAL SANDOR
IPC: A63F9/10
Filed: 1982-10-20
Abstract: Logic game with a plurality of game planes comprising mosaic units which may be placed side by side and/or one on top of the other, those mosaic units being provided of code carrier surfaces forming game surfaces coinciding with each other in various game planes. The present invention is characterized in that the mosaic units (6) are comprised of at least two spatial figures (4) which cover each other partially or completely and are interconnected in the covering plane; said figures are formed by spatial figure portions (2) joined in various ways to each other and presenting a base surface (2/a, 2/b etc.) having various shapes, at least a portion of the base surfaces (4/1', ...4/20') of the spatial figures (4) being formed as a code carrying surface.
Patent HU-206005-B (HU)
Inventor: BALINT JANOS
IPC: H04B3/36
Filed: 1989-07-20
Abstract: A találmány tárgya kapcsolási elrendezés átviteltechnikai berendezések vételirányú hangfrekvenciás jeleinek teljesítmény erősítésére, amelynek vezérlő bemenettel (11) rendelkező előfeszültség-elosztó vagy feszültség-előállító egysége (1) van. Az előfeszültség-elosztó vagy feszültség-előállító egysége (1) vezérlő bemenetére (11) vivőfeszültség (uj és egy telepes feszültségforrás tápfeszültségének fele (1/2 U.), első ki- menete (12) demodulátor (2) negyedik bemenetére (26), második kimenete (13) a demodulátor (2) harmadik bemenetére (25), a demodulátor (2) első és második bemenetére (21,22) moduláló feszültség (um) csatlakozik. A demodulátor (2) első és második kimenete (23,24) szűrő áramkör (3) második és első bemenetére (32, 31), a szűrő áramkör (3) első kimenete (33) első kondenzátor (Cl) egyik fegyverzetére, második  u 0« I 4. ábra HU 206 005 B A leírás terjedelme: 8 oldal (ezen belül 2 lap ábra)
Patent HU-208162-B (HU)
Title: Process for producing new proteins and pharmaceutical compositions comprising same
Inventor: LEMAIRE HANS-GEORG
IPC: C07K14/525
Filed: 1990-05-04
Abstract: PCT No. PCT/EP90/00719 Sec. 371 Date Sep. 26, 1991 Sec. 102(e) Date Sep. 26, 1991 PCT Filed May 4, 1990 PCT Pub. No. WO90/13575 PCT Pub. Date Nov. 15, 1990.Novel proteins which have a molecular weight of about 42,000 daltons and have at the N terminus the amino acid sequence Xaa Thr Pro Tyr Ala Pro Glu Pro Gly Set Thr Cys Arg Leu Arg Glu where X is hydrogen, a phenylalanine residue (Phe) or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe, and which are suitable for the treatment of diseases, are described.
Patent HU-186206-B (HU)
Inventor: ENGLER JOZSEF
IPC: C07D457/02
Filed: 1982-12-27
Abstract: A találmány tárgya új eljárás 6-metil-8-klórmetil-ergol-8-én előállítására, amely abban áll, hogy 6-metil-8-hidroximetil-ergol-8-én-t valamely aprotikus^poláris oldószerben gyenge szerves bázis savmegkötő jelenlétében 0—10 °C-on feleslegben vett metánszulfonsavkloriddal reagáltatnak, majd a reakció befejeződése után a metánszulfonsavklorid-felesleget elbontják, a terméket a reakcióelegyből extrahálással kinyerik és adott esetben kristályosítják, majd kívánt esetben átkristályosítják. A találmány szerinti új eljárás előnye, hogy egyszerűen jó kitermeléssel, nagytisztaságú anyagot állíthatunk elő. \ -1-
Patent HU-197065-B (HU)
Title: Method for increasing the recovery of vertically heterogeneous petroleum reservoirs working by gas drive
Inventor: MEGYERI MIHALY
IPC: E21B43/243
Filed: 1984-11-21
Abstract: A process for increasing the yield of crude oil reservoirs exploited by subterranean burning or by steam flooding. The process of the present invention is carried out by introducing an aqueous salt solution into the oil reservoir, then producing salt-crystals in the pores of the oil-bearing rock formation by total or partial elimination of the solvent, or by decreasing the solubility of the salt, and optionally resolving the salt-crystals separated out partially or totally by pressing in additional solvent, and optionally forming salt-crystals in an other part of the reservoir.
Patent HU-194780-B (HU)
Title: Pneumatic post station
Inventor: LANG HARTMUT
IPC: B65G51/26
Filed: 1984-11-30
Abstract: The pneumatic postal system consists of a network of pipes through which cylindrical slugs are driven by differential air pressure. The slug can be fed into the system or transferred from one pipe line to another at a station consisting of a rectangular frame with incoming and outgoing pipe branches (11,14,15). - The frame supports a cylindrical rotor (13) with a transverse bore (33) which follows a slightly curved path. In one position the rotor connects the pipes (11) to the pipe (14). By rotating the rotor so that the inlet (35) to the bore is aligned with the pipe (11), the inlet (36) is aligned with the pipe (15).
Patent HU-200547-B (HU)
Inventor: DUDUK VENDEL
IPC: A23K1/00
Filed: 1986-11-26
Abstract: A találmány tárgya eljárás hidratált, nagy energiatartalmú, növényi eredetű takarmányadalék előállítására, amikor is a 63-400 mikron szemcsenagyságú szójababot, extrahált szójababdarát, extrahált napraforgódarát, borsómagot, étkezési babot, édes csillagfúrtmagot vízben szuszpendálunk, a szuszpenzióhoz folyamatos kevergetés közben szárazanyagra számítva 1-5 tömegszázalék sósavat vagy kénsavat vagy foszforsavat adunk a szuszpenzió hőmérsékletét fokozatosan kevergetés közben 15-20 célszerűen 17 °C-ról 90 °C-ra növeljük, majd 2-3, célszerűen 2,5 órán át 91-95 °C hőmérsékleten tartjuk, végül a hidratált szuszpenziót 30 °C-60 °C hőmérsékleten porlasztva szárítjuk. HU 200547 A .4 leírás terjedelme: 6 oldal, rajz nélkül -1-
Patent HU-204881-B (HU)
Title: Process for producing filter aids, particularly oil filter aids and/or adsorbents
Inventor: CZUPINE FEJES KATALIN
IPC: C10G25/00
Filed: 1989-10-26
Abstract: Filter aids especially for oil filtration and/or adsorbents are prepd from a soln contg 0.5-20 g/l aluminium in Al2(SO4)3 and 20-130 g/l pref. 45-95 g/l free sulphuric acid pref the waste electrolyte from ''ELOXAL'' surface oxidising process for aluminium. The soln is neutralised to pH 6.0-7.0 by an alkali soln. contg a sodium base corresponding to at least 30 g/l pref. 40-50 g/l sodium-hydroxide, pref an aluminate from base-pickling of aluminium. Appts is obtd, which opt is rinsed free of sulphate ions, dried at 80-140 (100-110) degC and ground. The prod is heat-treated at 300-700 (350-500) degC for 1-5 hrs and opt shaped
Patent LV-10106-B (LV)
Title: Products and their application of method for design and synthesis of enteinizing hormone releasing hormone antagonists
Inventor: XIAO SHAOBO
IPC: C07K7/06
Filed: 1992-10-27
Abstract: This invention consists of two aspects: 1) the method of design and synthesis of LHRH antagonists; 2) the products thereafter obtained by using the above method. Taking (NAc-D2Na1<1>, DpClPhe<2>, D3Pal<3>, Ser<4>, Tyr<5>, DArg<6>, Leu<7>, Arg<3>, Pro<9>, DAla<10>)NH2 as the parent compound, a series of new analogs expressed as (NAc-D2Nal<1>, AA<2>, AA<3>, Ser<4>, AA<5>, AA<6>, Leu<7>, AA<3>, Pro<9>, DAla<10>)NH2 are obtained by fine modification of both lipophilic area and alkaline area of the molecule of the parent compound. In this way, the high antiovulatory activity of the parent compound can be maintained and the histamine releasing activity can be reduced to the level so as to meet the clinical requirement.
Patent LV-10837-B (LV)
Title: Cosmetically preparation for regeneration of skin and method for preparing thereofthod for controlling insects
Inventor: SZELES LAJOS
IPC: A61Q90/00
Filed: 1993-06-29
Abstract: A process for the preparation of a skin-regenerating or skin-protecting pharmaceutical composition is disclosed wherein the flower, root, fruit or cortex of a plant selected from the group consisting of Fugaceae, Caesalpiniaceae, Chenopodiaceae, and Rosaceae is extracted with ethanol at a temperature of 0 DEG  to 50 DEG  C. The obtained plant extract is purified and the dry substance content thereof is adjusted to 0.01 to 0.1% by adding more of the ethanol.
Patent LV-11910-B (LV)
Inventor: PAUL BROWN TREVOR
IPC: E01B9/48
Filed: 1997-08-13
Abstract: The invention concerns the fastening of railway rails. The purpose is to provide an exact positioning of the rail clamp, necessary for automating the process of fastening rails. The invention achieves this by the following means and actions: the rail fastening clamp is used, made from stick shape materials which bend in the form of an "n". The invention has parts which influence the fastening of a clamp for the clamp to be placed in a desirable assembly position. One of the variants of implementation of the invention is shown in fig. 11.<IMAGE>
Patent ME-00296-B (ME)
Title: PROCESS OF PURIFICATION OF hCG AND RECOMBINANT hCG PURIFIED BY THAT METHOD
Inventor: PARADISI GIANFRANCO
IPC: C07K14/59
Filed: 2001-01-22
Abstract: A process for the purification of recombinant human Chorionic Gonadotropin (hCG) from a sample of crude recombinant hCG in the supernatant of CHO cells comprises the combined use of ion-exchange chromatography and reverse phase HPLC.  The ion-exchange chromatography is performed twice and the final use of a size exclusion chromatography allows the purification from any residual traces of contaminants. The specific bioactivity of the highly purified hCG obtained from the process is particularly high, amounting to about 25.000 IU/mg.
Patent MX-168537-B (MX)
Title: Mejoras en molino para materiales solidos o pastosos
Inventor: MARIN MARIO E
IPC: B02C2/10
Filed: 1986-05-28
Abstract: La presente invención se refiere a mejoras en molino para materiales sólidos o pastosos, del tipo que comprende una tolva de alimentación, una cámara de molienda y una zona de descarga, con un rotor moledor dentro de la cámara de molienda movido por un accionador adecuado, las mejoras estando caracterizadas porque el molino comprende la asociación de un alimentador vertical del tipo de tornillo sinfin; una cámara de molienda en forma de doble cono formada por un par de conos huecos, estriados en su superficie interior, con sus bases confrontadas y un rotor de molienda estriado exteriormente y en forma de doble cono simétrico, con los dos conos unidos por sus bases y con una porción cilíndrica entre las dos bases de los conos, concéntricamente dispuesto por dentro de dicho par de conos de la cámara de molienda, dicha cámara de molienda proveyendo un espacio libre para material en molienda que disminuye en su espesor desde el vértice del primer cono hasta la base del mismo y que es de espesor constante a lo largo del cono inferior o segundo cono, siendo ajustable el grado de molienda por la provisión de un mecanismo de ajuste que separa o acerca simultáneamente ambos conos en el sentido axial de los mismos; un extractor de material molido, situado por el extremo inferior de dicha cámara de molienda y de forma de tornillo sinfin; una cámara deflectora cónica para recibir el material molido de dicho extractor; una charola receptora de material molido, que tiene una canalón de descarga en un punto de su periferia; dichos dos tornillos sinfin y dicho rotor de molienda estando colinealmente montados sobre una flecha vertical para  girar al unísono con la misma; y dicha flecha vertical estando acoplada en su extremo inferior a través de un reductor de velocidad, a un accionador que provee la fuerza motriz.
Patent MX-163639-B (MX)
Inventor: STREUBEL HANS
IPC: B22D11/04
Filed: 1987-01-20
Abstract: A mold is provided for continuously casting strip metal in which the mold cavity is formed with a flared mouth the internal surfaces of which terminate at their lower end along a transversely extending line, and the reflex angles which the mold along that line at a maximum near the center line of the mold and gradually diminishing toward the side edges of the mold.
Patent MX-166715-B (MX)
Title: Metodo para instalar un tubo repuesto de material ermoplastico en una tuberia existente
Inventor: STEKETTE CAMPBELL HALL JR
IPC: F16L55/165
Filed: 1987-08-19
Abstract: La presente invención se refiere a método para instalar un tubo de respuesto de material termoplástico en una tubería existente, que es substancialmente rígido a las temperaturas del medio ambiente, caracterizado en que comprende las etapas de; proporcionar el tubo de reemplazo en una abertura de acceso a la tubería existente en una forma colapsada y reducida; el tubo de reemplazo es manufacturado en una forma colapsada y reducida tal que el tubo de reemplazo retiene una memoria para una forma colapsada y reducida en donde la dimensión máxima es menor que el diámetro interior de la tubería existente, calentar un tramo del tubo de reemplazo mientras está en la forma colapsada y reducida para hacer flexible longitudinalmente el tubo de reemplazo, insertar un extremo delantero del tubo de reemplazo en la tubería existente, colocar el tubo de reemplazo dentro de la tubería existente, expandir el tubo de reemplazo de su forma colapsada y reducida a una forma expandida mediante la aplicación de calor y presión interna al tubo de reemplazo colapsado y reducido, y permitir que se enfrie el tubo de reemplazo y se vuelva rígido y estable en la forma expandida dentro de la tubería existente.
Patent MX-171117-B (MX)
Title: Composicion producto para la desfoliacion de plantas
Inventor: RUSCH REINHART
IPC: A01N43/828
Filed: 1987-12-18
Abstract: La presente invención se refiere a composición para la desfoliación de plantas, caracterizada porque contiene una mezcla hecha de los siguientes componentes: A) 1-fenil-3-(1,2,3-tiadiazol-5-il)-urea; B) una amida de ácido carboxílico o fosfato de tributilo; y C) 3-(3,4-diclofenil)-1,1 dimetil urea en una proporción tal que por cada parte por peso del componente A, hay de 1 a 200 partes por peso del componente B y de 0.1 a 20 partes por peso del componente C.
Patent NO-141336-B (NO)
Title: Slipemaskin.
Inventor: HOGLUND NILS OVE
IPC: B23Q35/10
Filed: 1972-05-25
Abstract: Slipemaskin.
Patent NO-150639-B (NO)
Inventor: RODRIGUEZ LUDOVIC
IPC: C07D227/087
Filed: 1979-05-03
Abstract: New lactam-N-acetic acids and amides thereof having the formula <IMAGE>    wherein R1 and R2=H, C1-C4-alkyl, aryl or halogen-substituted aryl, R3=OH or -NR4R5, R4 and R5=H, C1-C4-alkyl, cycloalkyl, aralkyl or, taken together with the N atom form alkyleneimino, oxa-alkyleneimino, aza-alkyleneimino or N-benzyl-aza-alkyleneimino, m is 3, 4 or 5, preferably 3, n is 0, 1 or 2, preferably 2; and the pharmaceutically acceptable salts of said acids. Processes for producing these compounds and pharmaceutical compositions containing the same are also given. These compounds show amongst others beneficial activity on the mnemic processes and cardiac activity.
Patent NO-155771-B (NO)
Title: Analogifremgangsmaate for fremstilling av terapeutisk aktive aminopropanolderivater.
Inventor: FRANKE ALBRECHT
IPC: C07D211/46
Filed: 1982-09-17
Abstract: Farmakologisk aktive aminopropanolderivater med formel I:. hvor. R 1 og R 2 betyr hydrogenatomer, alkyl-, cykloalkyl-, alkenyl-, alkynyl- eller hydroksyalkyl-rester, alkoksyalky1-, alkyltio-alkyl- eller dialkylaminoalkyl-rester, eller fenylalkyl- eller fenoksyalkyl-rester hvor fenylresten eventuelt er substituert med alkyl eller alkoksy, eller. 1 2. R og R sammen med nitrogenatomet som forbinder dem, danner. en 5- til 7-leddet mettet heterocyklisk ring som eventuelt kan være substituert og kan inneholde et ytterligere oksygen- eller ndtrogenatom som heteroatom i ringen,. R^ er et hydrogenatom, en alkylrest, et halogenatom, en hydroksygruppe eller en alkoksygruppe,. Rer et hydrogenatom, en alkylrest, et halogenatom, en alkoksyrest eller resten NR^R6, hvor R^ og R^ er like eller forskjellige og utgjør alkylrester eller sammen med det nitrogenatom som de er bundet til, danner en heterocyklisk ring, idet restene 13 4 2. R , R og R ikke samtidig kan være hydrogenatomer derscm R utgjør en alkylrest med 3-4 C-atomer, og. n er 1, 2 eller 3.Forbindelsene er særlig egnet som antiarytmika. Fremstilling av forbindelsene er beskrevet.
Patent NO-163992-B (NO)
Inventor: ZEMELMAN VALERY B
IPC: A23F5/36
Filed: 1986-03-10
Abstract: A process for producing an agglomerated instant coffee product having a roasted and ground apperance comprising;a. milling spray-dried instant coffee to produce a milled powder of an average particle size of 25 to 75 microns;b. adjusting the cohesiveness of the powder so that it will flow and will bind together with slight compaction;c. forming a regular shaped, loosely bound, structurally intact cluster from the cohesive adjusted powder, said cluster have a size of 800 to 2100 microns;d. fusing the outer surface of the cluster to a depth of from 5 to 30 microns; ande. drying and screening the fused clusters to produce an agglomerated instant coffee having a density of from 0.20 to 0.28 gms/cc, a hardness value of less than 8, a color of 17 to 24 Lumetron units and an average agglomerate size of from 800 to 1,300 microns.When this process is employed, an agglomerate instant coffee is produced at commercially acceptable rates which has a dark color, a fused surface and a size giving the appearance of roasted and ground coffee. Furthermore, the product has a light density yielding about one cup of coffee per teaspoon of instant coffee.
Patent NO-173245-B (NO)
Title: Funksjonell vaeske med borerte epoksyder, karboksyliske opploeseliggjoerere, sinksalter og kalsiumkomplekser
Inventor: BAYLES JR FREDERICK L
IPC: C10N60/12
Filed: 1987-10-16
Abstract: Multiformåls funksjonelt fluid bestående av en hovedmengde av en hydrokarbonolje og en mindre mengde, tilstrekkelig til å forbedre egenskapene i fluidet, av et nytt additiv. ..Dette består av et kalsiuasaltkompleks, et gruppe II metallditiofosfatsalt, et borert epoksyd og en karbok-syl isk oppløseliggjerer. Kalsium—saltet foreligger fortrinnsvis i form av et overbaset kalsiumsulfonat-salt, antislitasjemidlet er fortrinnsvis i form av et sink—ditiofosfat, det borerte epoksyd fortrinnsvis reaksjonsproduktet av borsyre og et 16-karbon,-epoksyd og den karboksyliske oppløselliggjorer er fortrinnsvis i form av et reaksjonsprodukt av et acyleringsmiddel inneholdende en substituert hydrokarbylbasert substituent inneholdende ca. 12-500 karbonatomer.Andre komponenter som viskositetsforbedrere og anti-skuxomingsmidler er generelt tilstede i fluidet.' Det resulterende fluid har forbedret lavtemperaturfluidi-tet og filtrerbarhet, forbedret EP/antislitasjeytelse, utmerkede friksjonsforbedrende egenskaper, antihakking-segenskap og er videre istand til å godkjennes i hydraulikk/transmisjonsprover, servostyring og bremse-kapasitetsprever. Disse trekk opprettholdes samtidig uten at man skader andre onskede ytelsesegenskaper i fluidet. EP/antislitasjeytelsen opprettholdes samtidig med antikorrosjonskarakteristika og transmisjonsytel-sesegenskaper. Den forbedrede vanntoleranse opprettholdes samtidig med den forbedrede EP ytelse.
Patent NO-176884-B (NO)
Inventor: HECKL KONRAD
IPC: C12N15/62
Filed: 1988-03-11
Abstract: A genetic engineering method for the production of human Mn superoxide dismutase (hMn-SOD), the DNA sequences which code for this enzyme, suitable vectors which contains these DNA sequences and host cells which can express these DNA sequences, as well as the enzyme hMn-SOD itself are described. Proposals for the use of this enzyme are additionally described.
Patent NO-176655-B (NO)
Inventor: VICTOR CARL-GUSTAV
IPC: B60C/
Filed: 1993-02-11
Abstract: An arrangement for retaining a tire on a vehicle wheel. The arrangement has a device for locking a tire against the wheel rim and pressing the tire beads against the rim flanges and rim seats. The device for locking the tire includes a plurality of clamping jaws disposed in spaced-apart relation to one another about the rim. Each jaw is rotatable about a clamping bolt. The rim of the wheel is provided, on its bottom, with fixing lugs. The jaws, when in an operative position, are applied against the fixing lugs to prevent the jaws from rotating about their clamping bolt.
Patent NO-179673-B (NO)
Inventor: WEICHERT ANDREAS
IPC: C07C315/04
Filed: 1993-06-30
Abstract: Benzoylguanidines of the formula I <IMAGE>  with   R(1) equal to R(4)-SOm or R(5)R(6)N-SO2- with R(4) and R(5) equal to alk(en)yl, -CnH2n-R(7), and with R(7) equal to cycloalkyl or phenyl, where R(5) can also mean H, R(6) equals H or C1-C4-alkyl,   R(2) is hydrogen, (cyclo)alk(en)(yn)yl, aryl and hetaryl   R(3) is defined as R(2),  and their pharmaceutically tolerated salts, are described. Compounds I are obtained by reacting compounds of the formula II <IMAGE> with guanidine, in which L is a leaving group which can easily undergo nuclophilic substitution. Compounds I are outstandingly suitable as antiarrhythmic drugs with cardioprotective component for the treatment and prophylaxis of infarct and for treating angina pectoris, and they also greatly reduce preventively the pathophysiological processes in the development of ischaemia-induced damage. Furthermore, I are distinguished by a potent inhibitory action on cell proliferation. They can thus be used as antiatherosclerotics, remedies for the late complications of diabetes, cancers, fibrotic disorders such as pulmonary, hepatic or renal fibrosis. They are effective inhibitors of the cellular sodium-proton antiporter (Na<+>/H<+> exchanger).