baber/WOPTO huggingface dataset:
Patent DE-68915226-T2 (DE)
Inventor: AOKI NOBUO
IPC: A61K35/22
Filed: 1989-08-18
Granted: 1995-01-05
Abstract: Novel thrombin-binding substances (A) and (B) are disclosed. The thrombin-binding substances have the following characteristics:     (a) molecular weight:     Thrombin-binding substance (A):  90,000-92,000 under reduced conditions  55,000-58,000 under unreduced conditions   Thrombin-binding substance (B):  98,000-105,000 under reduced conditions  60,000-65,000 under unreduced conditions     (b) isoelectric point:     Thrombin-binding substance (A): pH 6.0-6.8   Thrombin-binding substance (B): pH 5.8-6.5     (c) affinity: strong affinity to thrombin   (d) activity:   (1) capable of promoting the thrombin catalyzed activation of protein C   (2) prolongs clotting time; and   (e) stability: stable to denaturing agents (sodium dodecylsulfate and urea).   The thrombin-binding substances are useful as a medicine for curing thrombosis.
Patent DE-68917217-T2 (DE)
Inventor: LAFFERTY JOHN JOSEPH
IPC: C07D495/06
Filed: 1989-05-26
Granted: 1994-12-01
Abstract: Alpha-adrenoceptor antagonists having the formula: <CHEM> which are useful to produce  alpha -adrenoceptor antagonism, pharmaceutical compositions including these antagonists, and methods of using these antagonists to produce  alpha -adrenoceptor antagonism in mammals.
Patent DE-68918524-T2 (DE)
Inventor: OYA EIICHI C O NISSAN CHEMICAL
IPC: C07D231/20
Filed: 1989-07-11
Granted: 1995-05-04
Abstract: A pyrazole derivative of the formula I <CHEM> wherein A is C1-C4 alkyl, C2-C4 alkenyl or C2-C4 alkynyl; B is hydrogen, C1-C3 alkyl, halogen, C1-C3 haloalkyl, C1-C3 alkoxy, C1-C3 alkylthio, C2-C4 alkoxyalkyl, C2-C4 alkylthioalkyl or C2-C4 alkoxycarbonyl; X is C1-C6 alkyl, C1-C6 alkoxy, halogen, nitro, cyano, etc.; Y is -OR<1> (wherein R<1> is C3-C8 cycloalkyl, etc), -O-L-O-R<1> (wherein L is C1-C6 alkylene which may be substituted by C1-C3 alkyl), -O-L-OH, -O-L-O-L-O-R<2> (wherein R<2> is hydrogen, C1-C6 alkyl group, etc.), -O-L-R<3> (wherein R<3> is phenyl which may be substituted by C1-C3 alkyl, etc.), -O-M (wherein M is a 3- to 6-membered alicyclic group), -O-L-M, -O-L-NR<4>R<5> (wherein each of R<4> and R<5> is hydrogen or C1-C6 alkyl, or R<4> and R<5> form a ring together with the adjacent nitrogen atom), -O-L-COOR<4>, -O-CH=CH-COOR<4>, -O-L-CN, -O-L-C(O)-R<2>, -O-L-S(O)n-R<4> (wherein n is an integer of from 0 to 2), -O-COOR<4>, -O-CONR<4>R<5>, -OP(O)(OR<4>)2, -S(O)nR<1>, or -S(O)n-L-O-R<1>; Z is halogen, nitro, C1-C3 alkoxy, etc.; V is hydrogen, halogen, C1-C4 alkyl or C1-C4 alkoxy; W is hydrogen, halogen, C1-C4 alkyl, etc.; Q is hydrogen, C1-C6 alkyl which may be substituted by halogen, ... -C(O)-R<7> (wherein R<7> is phenyl which may be substituted), -S(O)2R<7>, -P(O)(OR<7>)2, -L-C-(O)-R<7>, -L-C(O)-N(R<8>)(R<9>) (wherein each of R<8> and R<9> is hydrogenor C1-C6 alkyl), -L-R<1><0> (wherein R<1><0> is phenyl group may be substituted, C1-C6 alkyl, C1-C6 alkoxy, or hydroxyl), -L-N(R<8>)(R<9>), -L-OR<1><1> (wherein R<1><1> is hydrogen, C1-C6 alkyl, or C1-C6 alkenyl), -L-OC(O)R<1><2> (wherein R<1><2> is C1-C6 alkyl or C1-C6 alkoxy), -L-S(O)nR<1><1>, -L-SC(O)R<8>, <CHEM> (wherein each of L1 and L2 is methylene, oxygen or sulfur, R<1><2> is hydrogen or C1-C3 alkyl, and m is 2 or 3); and a salt thereof.
Patent DE-68922346-T2 (DE)
Inventor: DIKSTEIN SHABTAI
IPC: A45D40/04
Filed: 1989-06-19
Granted: 1995-10-12
Abstract: A dispensing container (10) for a viscous substance comprising a sleeve (12) defining an axis of rotation (30) and having a pair of ends arranged at first and second locations along the axis, the sleeve (12) further defining a helical travel path (24) on an inward facing surface thereof: a dispensing member (16) mounted in association with one of the pair of ends of the sleeve; a piston head (26) mounted within the sleeve (12) and defining an outward facing peripheral surface operative to cooperate with the helical travel path (24) and further defining with the dispensing member (16) and a portion of the sleeve (12) extending therebetween a storage volume for the viscous substance, the piston head (26) being operative to travel along the axis of rotation (30) when undergoing rotation thereabout relative to the sleeve (12); linkage apparatus (36) integrally formed with the piston head (26) and defining an end portion associated with a predetermined portion of the sleeve, the linkage apparatus (36) permitting axial displacement of the piston head (26) relative to the predetermined portion proportional to the distance between the predetermined portion and the dispensing member (16); and apparatus (41,42) ging the end portion of the linkage apparatus and thereby preventing simultaneous rotation of the piston head and the sleeve in the same direction.
Patent DE-68924187-T2 (DE)
Inventor: FREEBURG THOMAS A
IPC: H04W92/02
Filed: 1989-01-30
Granted: 1996-05-02
Abstract: A unique cellular data telephone system includes a cellular telephone system (CTS 150), a cellular data switch (CDS 170), and a telephone central office (130) for providing both voice and data telephone services to portable and mobile cellular data telephones (CDTs 102, 122) located anywhere in a large geographical area. Each of the CDTs (102, 122) includes a data control unit (DCU 106), a cellular modem (162) and a cellular telephone (108) and associated antenna (110), and connects to a data terminal (104, 124) with keyboard and display. DCU (106) includes memory (302) for storing a CDS telephone number and CDT telephone number, microcomputer (304) with internal memory for controlling data communications between cellular modem (162) and data terminal (104), a duel tone multifrequency ("DTMF") encode (306) for encoding telephone numbers and control signals, a DTMF decoder (314) for decoding DTMF telephone digits and/or DTMF control tones, a buffer (312) for storing transmit data from data terminal (104), and analog switches (308, 310) for coupling DTMF encoder (306) and buffer (312) to the transmit data Td signal to cellular modem (162). If data transmit (104) is inactive for a predetermined time interval, DCU (106) automatically disconnects the cellular telephone call while maintaining the landline telephone call to a data host (140, 141). Once data is transmitted again by data terminal (104), DCU (106) automatically places another cellular telephone call and is reconnected to the landline telephone call.
Patent DE-68924278-T2 (DE)
Inventor: RAMM ERIC
IPC: G21F9/00
Filed: 1989-09-27
Granted: 1996-02-15
Abstract: The present invention relates to the hot pressing of particulate materials and containers for use in such processes. The container (10) is generally cylindrical and has a first closed end (12) and a second end closed by a lid (13) after it has been filled with particulate material (23). The side wall brackets (11) include reduced diameter portions (17) positioned between generally cylindrical portions (15, 16). Radially inwardly directed portions (18) extend between reduced diameter portions (17) and the cylindrical portions. Reinforcing rings (33) may be positioned in the reduced diameter portions (17) if desired. When a container is pressed it undergoes significant axial compression and the radially inwardly directed portions (18) close to approach or contact one another.
Patent DE-68925996-T2 (DE)
Inventor: HABIB MAHER
IPC: A23L23/00
Filed: 1989-06-05
Granted: 1996-10-02
Abstract: Substantially non-aggregated casein micelles are employed as a fat substitute in food products. The concentrated casein micelles can replace all or a portion of the fat or cream in food products such as frozen dairy desserts, icings, puddings, whipped toppings, fortified skim milk, dips, spreads and sauces.
Patent DE-69005620-T2 (DE)
Inventor: EMORINE LAURENT
IPC: C07H21/04
Filed: 1990-01-25
Granted: 1994-07-21
Abstract: PCT No. PCT/FR90/00054 Sec. 371 Date Sep. 3, 1991 Sec. 102(e) Date Sep. 3, 1991 PCT Filed Jan. 25, 1990 PCT Pub. No. WO90/08775 PCT Pub. Date Aug. 9, 1990.Novel polypeptides having a (beta)-adrenergic receptor activity containing the sequence of 402 amino acids, or a fragment of this sequence, said fragment being such that, in particular, either it nonetheless includes the sites contained in said sequence and whose presence is necessary so that, when the fragment is exposed to the surface of a cell, it is capable of participating in the activation of the cyclase adenylate in the presence of an agonist, or it is likely to be recognized by antibodies which also recognize the above succession of 402 amino acids, but fail to recognize the (beta)1 adrenergic receptor and the (beta)2 adrenergic receptor. These polypeptides are useful for screening drugs which act on said polypeptides and for treating obesity, fat diabetes and hyperlipidemias.
Patent DE-69007906-T2 (DE)
Inventor: RANCANI CLAUDIO
IPC: A61M1/00
Filed: 1990-08-02
Granted: 1994-10-20
Abstract: The present valve, employable by persons affected by hydrocephalus, permits discharge into suitable offtake branches of the excess cephalorhachidian fluid existing in the ventricles of the brain. The valve basically consists of a hollow cylindrical body (1) having inside a seat (5) with an enlarging triangular shape designed to interact with an aptly-shaped capsule or small piston (6) and placed against an antagonist spring (7). This pattern permits to offset the varying amounts of ventricular fluid pressures, discharging outside any fluid, whether large or small, through suitable offtake branches and at the same time it accomplishes a self-cleaning function which ensures a constant flow efficiency.
Patent DE-69011128-T2 (DE)
Inventor: LUXENBERG ROBERT
IPC: A63F3/08
Filed: 1990-12-10
Granted: 1995-01-12
Abstract: A method of determining the winners of, for example, a game of skill in conjunction with a football or baseball game without the input of all the scores is provided. By the use of statistical sampling a small fraction of the remote players upload their scores to a central station via a telephone line, for example. Then, when the tentative winners are determined from this small statistical sample, the mass communications link of the system downloads the statistical curve to all of the players and only those players who are equal or better than the winning score telephone. Thus, time and money are saved for the telphone up-link. Furthermore, overcrowding of the telephone system is avoided by a proper delay given the individual remote sources.
Patent DE-69014694-T2 (DE)
Inventor: GOULDING PETER
IPC: A61B5/08
Filed: 1990-04-11
Granted: 1995-06-08
Abstract: A method and apparatus for measuring a parameter of a test gas in isolation from gas pressure fluctuations. A pump draws the test gas through an air capacitor into a sensor, storing the gas in the capacitor. A valve closes a fluid flow path which admits the test gas to the air capacitor and opens a fluid flow path between the air capacitor and a constant pressure alternate gas source, isolating the air capacitor and the sensor from pressure fluctuations in the test gas. The air capacitor prevents any mixing of the test gas with the alternate gas until measurement of the unknown parameter has been accomplished.
Patent DE-69018094-T2 (DE)
Inventor: BOEN PER
IPC: B29C48/09
Filed: 1990-12-17
Granted: 1995-11-23
Abstract: PCT No. PCT/NO90/00190 Sec. 371 Date Jun. 4, 1992 Sec. 102(e) Date Jun. 4, 1992 PCT Filed Dec. 17, 1990 PCT Pub. No. WO91/08891 PCT Pub. Date Jun. 27, 1991.This invention is directed to a lubricating arrangement for a plastic extruder (1) for production of cylindrical plastic tubes with a smooth inner surface. The plastic extruder (1) includes a mandrel which consists of a die core (6) which is a cylindrical coaxial extension of an extruder screw (2). Die core (6) rotates together with said screw, and a stationary external die member (7). The lubricating arrangement is located in the external die portion for lubricating its forming surface. The lubricating arrangement has a plurality of radially directed plugs (11, 11', 17, 17'), each plug engaged in a bore (10) in the external die member. The inner end of the plug lies in the die surface. Lubricating ducts (13) are provided to the bore which are connected with a source of a lubricant, which supplies a lubricant under pressure.
Patent DE-69020692-T2 (DE)
Inventor: LOMBARDI MASSIMO
IPC: H02K15/09
Filed: 1990-08-22
Granted: 1995-11-02
Abstract: Methods and apparatus for marking and identifying a commutator hook of an electric motor are provided. A preselected commutator hook is marked by deforming the hook while the armature is in a winding machine, with a known angular position. The marked hook is identified by apparatus which determines whether or not the hook has been deformed while in the winding machine, and thereby recognizing the hook. <IMAGE>
Patent DE-69106985-T2 (DE)
Inventor: HODEK ROBERT BATON
IPC: E06B3/667
Filed: 1991-08-29
Granted: 1995-08-03
Abstract: An insulating unit (150) has a pair of glass sheets (12,14) about an edge assembly (152) to provide a compartment (18) between the sheets. The edge assembly has a U-shaped spacer (158) made of metal, metal coated plastic, gas and moisture impervious polymer, or gas and moisture impervious film coated polymer. The outer legs (156) of the spacer (158) and the glass (12,14) provide a long diffusion path to limit the diffusion of argon gas out of the compartment (18). The edge assembly (152) has materials selected and sized to provide edge assembly having an RES-value of at least 75. A spacer (158) for use in insulating units includes a plastic core having a gas impervious film e.g. a metal film or a halogenated polymer film. Also taught herein are techniques for making the unit (150) and spacer (158). The unit (150) has a long diffusion path to increase the time period in which insulating glass e.g. Argon gas may be retained in the compartment (18). The increased RES-value provides a unit (150) that has a low thermal conducting edge (152). In this manner heat loss through the marginal edge (152) of the unit (150) is reduced. <IMAGE>
Patent DE-69111574-T2 (DE)
Inventor: ITO YASUO
IPC: A61P1/10
Filed: 1991-11-26
Granted: 1996-01-18
Abstract: A pharmceutical composition capable of being disintegrated in an acidic environment, which comprises calcium polycarbophil and 1 to 80 % by weight of a cellulose derivative such as carboxymethylcellulose or low substituted hydroxypropylcellulose based on the calcium polycarbophil. The pharmaceutical composition in a form of a tablet, a capsule, or granules is useful as a bulk-forming laxative or an antidiarrheic agent since it can be disintegrated readily in the stomach and form a complete dispersion of polycarbophil in the digestive tract.
Patent DE-69113424-T2 (DE)
Inventor: KAJIWARA KEN-ICHI
IPC: F04D1/06
Filed: 1991-12-23
Granted: 1996-05-23
Abstract: A multistage centrifugal pump has a plurality of series-connected interstage casings of pressed sheet metal housing respective impellers. Each of the interstage casings includes a cylindrical side wall for housing an impeller, a bottom wall joined to the cylindrical side wall and extending around an inlet for the impeller, and a return blade attached to the bottom wall remotely from the impeller. The bottom wall has a central region projecting conically or spherically radially inwardly toward the impeller by a distance corresponding to the extent to which the bottom wall is deformable under an interstage pressure difference. The deformation of the bottom wall that is developed under the pressure generated by the impeller is borne by the casing body itself only, without affecting the welded spots, which are prevented from being ripped off under stresses that would otherwise concentrate on the welded spots.
Patent DE-69114013-T2 (DE)
Inventor: LOCHTEFELD J THOMAS
IPC: A63G3/00
Filed: 1991-09-04
Granted: 1996-10-17
Abstract: A water ride attraction is disclosed which utilizes a containerless riding surface to eliminate disadvantageous boundary layer effects. A sheet flow of water is directed up the incline to produce a simulated wave. The configuration and contour of the riding surface and the various flow parameters can be widely varied to produce numerous desirable wave conditions.
Patent DE-69129302-T2 (DE)
Inventor: IWATA KENNETH
IPC: A61K35/44
Filed: 1991-06-25
Granted: 1998-12-03
Abstract: The present invention provides (1) an antibody which (a) specifically binds to human TGF- beta 3 and (b) exhibits substantially no cross reactivity with TGF- beta 1 or TGF- beta 2 and (2) antibodies directed against the pro region of the TGF- beta  precursor. Further, this invention provides a pharmaceutical composition comprising the pro region of the TGF- beta  precursor. Also, this invention provides methods for diagnosing, detecting and treating subjects suffering from disorders associated with TGF- beta 3.
Patent DE-69209386-T2 (DE)
Inventor: CAUPIN HENRI-JEAN
IPC: A61P33/14
Filed: 1992-06-19
Granted: 1996-10-02
Abstract: The use of derivatives of specific acids for the manufacture of a pediculicidal medicament. The invention is characterised in that it comprises an effective quantity of one or more non-ionic lipophilic derivatives and/or ionic hydrophilic derivatives of undecylenic acid or undecanoic acid. The non-ionic lipophilic derivatives preferably consist of esters of this undecylenic acid or this undecanoic acid with a C1-C16 monoalcohol containing no other OH functional group than that which reacts with the COOH functional group of the undecylenic acid. The ionic hydrophilic derivatives preferably consist of alkali metal or alkaline-earth metal salts.
Patent DE-69211108-T2 (DE)
Inventor: THIL ALBERT
IPC: E04H4/06
Filed: 1992-12-23
Granted: 1997-01-16
Abstract: This invention concerns a covering device for a swimming pool, which can be moved vertically inside the pool (1) of the swimming pool, between two extreme positions, i.e. the bottom (7) and the surface of the pool, under the action of means of movement (17), this device comprising closing shutters mounted to move on a support structure (9) in such a way as to be able to occupy an opening position and a closing position. This device is characterized in that the support structure (9) is plane and rigid and forms many cells, each cell being able to be closed by at least one shutter, the means of movement (17) being able to position and hold the support structure (9) in at least a third position, situated between the abovementioned extreme positions. <IMAGE>
Patent DE-69211408-T2 (DE)
Inventor: OKADA GORO
IPC: B65G47/64
Filed: 1992-03-31
Granted: 1996-10-10
Abstract: A conveying system splits a stream of articles into three substreams. The system includes an infeed conveyor (12) which conveys articles and aligns their centers of gravity along a central axis. A steering mechanism (16) receives the articles and steers them selectively in one of three directions toward an outfeed conveyor arrangement (14). The outfeed conveyor arrangement (14) includes a mouth (90) formed by the intersection of three outfeed conveyors (14) arranged to receive articles from the steering rollers (20,22,24). A centrally located one (92) of the outfeed conveyors (92,94,96) occupies less than one-third of the transverse width of the mouth (90), and each of the other two outfeed conveyors (94,96) occupies more than one-third of the transverse width of the mouth (90). The steering rollers (20,22,24) are turned by a fluid actuated mechanism (60) which comprises two fluid cylinders (62,64) affixed together in back-to-back relationship.
Patent DE-69212707-T2 (DE)
Inventor: FANTACCI TOSCO
IPC: B26D/
Filed: 1992-05-15
Granted: 1997-02-06
Abstract: An installation for crushing vehicle tires and the like and for separating the metal parts from the nonmetal parts comprises in combination: a first crusher unit (1); a first screening assembly (27) associated with said first crusher unit (1), to divide the granules into at least two groups, depending on their size; a separation section (35) to separate the metallic material from the larger granules originating from said first screening assembly (27) and to recirculate the nonmetallic material; a second crusher unit (71) which receives the granules of smaller size originating from the first screening assembly and the granules of nonmetallic material originating from said separation section (35); and downstream from said second crusher unit, a first separator means (83) to separate the metal parts from the nonmetal parts. <IMAGE>
Patent DE-69213739-T2 (DE)
Inventor: RON EYAL
IPC: A61K38/00
Filed: 1992-06-22
Granted: 1997-02-20
Abstract: PCT No. PCT/US92/05309 Sec. 371 Date Jun. 29, 1993 Sec. 102(e) Date Jun. 29, 1993 PCT Filed Jun. 22, 1992 PCT Pub. No. WO93/00050 PCT Pub. Date Jan. 7, 1993A composition comprising a pharmaceutically acceptable admixture of an osteogenic protein; a polymer matrix component selected from the group consisting of poly(lactic acid), poly(glycolic acid), and copolymers of lactic acid and glycolic acid; and an osteogenic protein-sequestering material.
Patent DE-69213741-T2 (DE)
Inventor: WANDERS BERNARDUS FRANCISCUS M
IPC: A45C11/04
Filed: 1992-06-18
Granted: 1997-03-06
Abstract: PCT No. PCT/NL92/00107 Sec. 371 Date Dec. 8, 1993 Sec. 102(e) Date Dec. 8, 1993 PCT Filed Jun. 18, 1992 PCT Pub. No. WO93/00027 PCT Pub. Date Jan. 7, 1993.A container for storing at least one contact lens (12) comprises at least one receiving means (1), one side wall of which is provided with an opening providing access to a receiving space (11) within the receiving means the contact lens is to be received in, a closing means (2) for closing the opening, and a supporting means (13) being integral with said closing means and serving to support the contact lens. The receiving means (1) comprises two at least substantially flat wall parts (3, 4) and wall joint parts (5, 6, 7) joining said wall parts, while a space defined by said wall parts constitutes the receiving space. Additionally, a contact lens storage apparatus designed for storing a plurality of containers according to the invention is provided.
Patent DE-69221276-T2 (DE)
Inventor: MIYAO MAKIJI
IPC: B29C70/08
Filed: 1992-12-11
Granted: 1998-01-22
Abstract: A hybrid laminated prepreg comprises a resin layer (2), a decorative layer (3) laminated thereon and having a decoration (7), and a transparent prepreg layer (4) laminated on the decorative layer (3). In manufacturing a fiber reinforced composite resin material molding, the hybrid prepreg is laminated in a couple of layers on the outermost one of the laminated layers of usual structural prepreg. With the hybrid prepreg it is possible easily to decorate the molding, to obtain a stable and durable decoration and also dispense with time-consuming operations of coating and finishing. The hybrid laminated prepreg can be used for fiber reinforced composite resin moldings, for instance for such sporting goods articles as golf club shafts, tennis rackets, ski pole shafts and fishing rods, fancy articles, briefcases such as attache cases, tubing such as for bicycle frames and decorative wall panels. <IMAGE>
Patent DE-69303943-T2 (DE)
Inventor: SAKAI YASUYOSHI
IPC: C12R1/865
Filed: 1993-02-26
Granted: 1997-01-30
Abstract: The present invention relates to an expression vector which is induced by methanol and/or glycerol utilizing an alcohol oxidase gene of a methylotrophic yeast; a recombinant methylotrophic yeast containing said vector and capable of accumulating a significantly high amount of an expression product of a heterologous gene; and a method for producing useful products utilizing said recombinant. The expression vector is constructed by utilizing the promoter and terminator of an alcohol oxidase gene of methylotrophic yeast. Further, a significantly high amount of adenylate kinase, cytochrome C552 or peroxidase is produce by using said expression vector.
Patent DE-69304482-T2 (DE)
Inventor: KUHN DAVID GEORGE
IPC: A01N43/36
Filed: 1993-06-11
Granted: 1997-02-20
Abstract: There are provided N-aminoalkylcarbonyloxyalkylpyrrole compounds of formula I <CHEM> and their use for the control of insects, acarina and mollusks. Further provided are compositions and methods comprising those compounds for the protection of plants from attack by insects, acarina and mollusks.