baber/WOPTO huggingface dataset:
Patent IE-782240-L (IE)
Title: Telescopic truck body having ejection bulkhead
IPC: B60P1/00
Filed: 1978-11-13
Abstract: A telescopic truck body 10 incorporating an ejection bulkhead 38. The telescopic truck body consists of two sections 14, 16 telescoped one within the other. A movable bulkhead 38 is located within the inner section of the telescopic body and a drive means 60 is provided for driving the bulkhead longitudinally of the inner section as the inner section is driven with respect to the outer section. The drive is adapted to move the bulkhead longitudinally of the inner section so that it is located adjacent the discharge end thereof when the inner section is fully telescoped within the outer section. <IMAGE>
[GB2007619A]
Patent IE-44304-L (IE)
Title: Threaded container closures
IPC: B65D53/02
Filed: 1976-12-21
Abstract: A liquid tight closure for containers comprising a threaded neck secured about a suitably formed opening in a container wall section. An annular sealing gasket is formed in situ on the exposed surface of the terminal thread area remote from the neck mouth. A closing member threadedly engages the container opening neck with the starting thread area of the closing member in sealing engagement with the neck gasket thereby sealing off the thread engagement upon full seating of the closing member.
[US4117949A]
Patent NO-774001-L (NO)
Title: Simulator for et maal som beveger seg i forhold til et bevegelig objekt
Inventor: CHERNOV BORIS P
IPC: G09B9/06
Filed: 1977-11-22
Abstract: Simulator for et mål som beveger seg i forhold til et bevegelig objekt.
Patent NO-800381-L (NO)
Title: Varmegjenvinningsanlegg.
Inventor: ROSENBERG JAN
IPC: F28F/
Filed: 1980-02-12
Abstract: Ved varmegjenvinningsanlegg (1) arbeider man med både fraluft. og tilluft, og her kan det ved lave utetemperaturer oppstå ned-isingsproblemer i selve den varmevekslende delert (5 og 6) av et anlegg (1). For å unngå nedising, oppvarmes tilluften før varmeveksling. For å styre oppvarmingen, finnes organ som føler tilluftens temperatur etter varmeveksling, og på basis av nevnte føling bedømmes temperaturen av den fraluft som kan utsettes for isdannelse. Ifølge foreliggende oppfinnelse derimot, plasseres et organ (17 resp. 13) som føler temperaturen av forbistrømmende luft og som påvirker oppvarmingen på en slik måte at fraluften etter varmeveksling med tilluften påvirker sistnevnte organ (17 resp. 18) på en slik måte at når risiko for nedising av fraluften foreligger, startes oppvarming av tilluften.
Patent NO-820095-L (NO)
Inventor: LINDAHL JONAS ARNE INGVAR
IPC: D21C9/02
Filed: 1982-01-13
Abstract: To provide a cleaner pulp and to obtain a higher chemical recovery during washing of chemically cooked and optionally defibrated cellulose pulp, the partially washed pulp is subjected to a mild mechanical treatment e.g. in a device (10) adapted for high-consistency treatment and provided with screwsrotating relative to each other, said treatment taking place between at least one pair of conventional washing stages (4,14).
Patent NO-833641-L (NO)
Inventor: JANSEN FRANZ
IPC: A61K39/395
Filed: 1983-10-06
Abstract: The present invention relates to drugs characterized in that they comprise, in association, at least one immunotoxin and at least one monovalent carboxylic ionophore.
Patent NO-841379-L (NO)
Inventor: GRIEWEL HORST-HUBERT
IPC: H02J7/10
Filed: 1984-04-06
Abstract: 1. Arrangement for the capacity-dependent recharging of an accumulator, comprising a current sensing device (1.5) for measuring the quantity of charge removed from the accumulator (1.1), the information of which device, concerning the quantity of charge removed, can be temporarilly stored in a memory (1.8) in which other circuit-specific data are stored, it being possible to transfer the data content from the memory (1.8) to a charging station (2) and supply it to an analysing device (2.4) which acquires the data transferred, processes them and by this means controls a control arrangement (2.3) in such a manner that the accumulateur (1.1) can be recharged from a voltage supply device (2.1), characterized in that the memory (1.8) and the analysing device (2.4) are separate from each other and can be connected to each other via charging contacts (A, B) and that the data exchange between the memory (1.8) and the analysing device (2.4) occurs via one transmit/receive component (1.6) each at the memory (1.8) and (2.2) at the analysing unit (2.4) via the charging contacts (A, B).
Patent NO-854096-L (NO)
Inventor: SCHILLING MICHEL
IPC: F42B10/40
Filed: 1985-10-15
Abstract: A device for reducing drag of a round of ammunition or projectile (1) comprises a gas-producing compound (3) such as a propergol, the combustion of which generates gases at a pressure of at least sufficient value to fill the low-pressure region which is formed at the rear end of a projectile and causes drag. The device comprises a gas-tight casing (2) containing the explosive compound (3) and an igniter (6) for initiating combustion of the compound. The casing comprises fasteners which cooperate with complementary fasteners (11) arranged at the rear end of the round of ammunition so as to permit gas-tight fitting of the casing at the rear end of the projectile, at any moment and in particular at the firing location, in order to reduce drag and to increase the range of the projectile.
Patent NO-860046-L (NO)
Inventor: STOLTEFUSS JUERGEN
IPC: C07D211/84
Filed: 1986-01-08
Abstract: 5-Aryl-1,4-dihydropyridines of the formula   <IMAGE>   in which R represents cycloalkyl, heteroaryl or aryl which is optionally substituted by at least one substituent independently selected from the group consisting of halogen, nitro, hydroxyl, amino, carboxyl, alkoxycarbonyl, cyano, acyl, acyloxy, acylthio, by alkyl, alkyloxy, alkylthio or alkylsulphonyl, each of which is optionally substituted by one or more halogens, by aryl which is optionally substituted by alkyl, alkoxy, halogen or nitro, or optionally by the group -Z-CH2-R4, where Z represents oxygen or sulphur, and R4 represents cycloalkyl, heteroaryl or aryl which is optionally substituted by halogen, cyano, nitro, hydroxyl, carboxyl, alkoxycarbonyl or by alkyl or alkoxy, each of which is optionally substituted by one or more halogens, R1 and R2 are identical or different and represent straight-chain or branched alkyl which is optionally substituted by aryl, carboxyl, alkoxycarbonyl or by hydroxyl, R3 represents nitro, cyano or the group   <IMAGE>   where A represents oxygen, sulphur or -N-R6, R6 represents hydrogen, phenyl or alkyl, and where R5 represents hydrogen, cycloalkyl or a hydrocarbon radical which is optionally interrupted in the chain by one or more carbonyl groups and/or sulphur and/or oxygen atoms and is optionally substituted by halogen, nitro, cyano, hydroxyl, mercapto, carboxyl, alkoxycarbonyl, aryl, acyloxy, acylthio, heteroaryl or by an amino group, the amino group carrying one or two identical or different substituents from the group comprising phenyl, alkyl or aralkyl, X and Y are identical or different and represent hydrogen, alkyl, alkoxy or alkoxycarbonyl, halogen, hydroxyl, nitro, carboxyl, cyano or trifluoromethyl or trifluoromethoxy, or physiologically acceptable salts thereof, are active on the cardiovascular system.
Patent NO-870199-L (NO)
Inventor: FRANCESCHINI JACQUELINE
IPC: C07D311/04
Filed: 1987-01-16
Abstract: The invention relates to new dihydrobenzofuran- and chroman-carboxamide derivatives of the general formula:   <IMAGE> (I) in which R and R' are each hydrogen or methyl; n is 1 or 2; m is 1 or 2; Z is either   <IMAGE> (a)   wherein R1 and R2 are lower alkyl, or <IMAGE> (b)  wherein R3 is alkyl, alkenyl, cycloalkyl-alkyl, cycloalkenyl-alkyl, X is H, NH2, methoxy, or methyl and Y is H, Cl, cycloalkylmethylsulfonyl, alkylsulfamoyl or alkylsulfonyl and to their pharmacologically acceptable acid addition salts and their optical isomers, to the processes for the preparation thereof and to the use thereof as medicaments, especially as neuroleptics.
Patent NO-871062-L (NO)
Inventor: GEISER MARTIN
IPC: A01N63/50
Filed: 1987-03-13
Abstract: The present invention is directed to a method for producing an insecticidal proteinaceous substance including the discovery and identification of the entire DNA sequence coding for the insecticidal protein MGE 1 of said proteinaceous substance, to said proteinaceous substance, to a DNA fragment characterized by the nucleotide sequence given in table 2, said fragment coding for the protein MGE 1, to the protein MGE 1 itself, to a DNA fragment originating from Bacillus thuringiensis var.kurstaki from Hpal (O) to Pstl (4355) coding for an insecticidal proteinaceous substance including truncated portions thereof, said truncated DNA portions being subject to the proviso that insecticidal activity has not been lost, to the method of constructing cloning vehicles and expression vehicles comprising the DNA fragment given in table 2 and also to said vehicles themselves.
Patent NO-880664-L (NO)
Inventor: FREI JOSEF
IPC: B03B9/06
Filed: 1988-02-16
Abstract: In the process, the garbage is treated before separation, if appropriate by comminution, water extraction and/or loosening. It is to be developed so that the parts consisting of non-conductive material can be removed simply and cost-effectively. This is achieved in that the refuse in the form of a heterogeneous material stream (8) of limited grain size is subjected, at a first station, to a treatment electrostatically charging the parts of non-conductive material and, at a subsequent second station, the electrostatically charged parts are extracted from the material stream (8) in the fluidised or suspended state of the latter by means of at least one receiver (5) of opposite electrostatic charge.
Patent NO-881710-L (NO)
Inventor: CARUSO MICHELE
IPC: C07C50/22
Filed: 1988-04-20
Abstract: Anthracycline glycosides of formula (I) and their pharmaceutically acceptable acid addn. salts are new where R1 = H or OH; one of R2 and R3 = H, the other is H or OH. Also new are the intermediates 4-demethoxy-4-amino -7-deoxy-daunomycinone (IX) and daunomycinones (II), opt. N-protected. - (I) is pref. 4-demethoxy-4 -amino-daunorubicin; 4-demethoxy- 4-amino-4'-epi-daunorubicin or 4-demethoxy-4-amino -4'-deoxy-daunorubicin, and the corresp. doxorubicin cpds.
Patent NO-892715-L (NO)
Inventor: PETERSEN UWE
IPC: C07D498/06
Filed: 1989-06-29
Abstract: 7-(1-Pyrrolidinyl)-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid and 7-(1-pyrrolidinyl)-1,4-dihydro-4-oxo-1,8-naphthyridin-3-carboxylic derivs. of formula (I), their hydrates, acid addition salts, as well as their alkali metal, alkaline earth, silver and guanidinium salts are new; X<1> = halo; X<2> = H, NH2, 1-4C alkylamino, di(1-3C alkyl)amino, OH, 1-4C alkoxy, SH, 1-4C alkylthio, arylthio or halo; R<1> = 1-4C alkyl, 2-4C alkenyl, 3-6C cycloalkyl, 2-hydroxyethyl, 2-fluoroethyl, OMe, NH2, MeNH, EtNH or Me2N; or is Ph (opt. mono- or disubstd. by F); R<2> = H, 1-4C alkyl or (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl; R<3> = a gp. of formula (a): R<4> = 1-4C alkyl, aryl or 1-4C acyl; R<5> = H, 1-4C alkyl, OH or OMe; R<6> = H, 1-4C alkyl (opt. substd. by OH), aryl, heteroaryl, benzyl, 1-4C alkoxycarbonyl, 1-4C acyl, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl or 3-6C cycloalkyl; R<7> = H or 1-4C alkyl; R',R'' = H, Me or Ph; R''' = H or Me; Y = O, CH2, CH2CH2 or CH2O (where the bond to N may be via C as well as O); (Note: Y is not otherwise defined in claim 1). Z = O or S; A = N or CR<8>; R<8> = H, halo, Me, CN, NO2 or OH, or R<8>+R<1> = a bridge of type (b)-(d): Cpds. of formula (e) are excluded; R1 = 1-4C alkyl; R2,R3 = H or 1-4C alkyl; R4 = cyclopropyl, Ph, halophenyl, thienyl, opt. substd. by 1-4C alkyl or halo; R5 = halo. Also claimed is the S,S-configuration of a cpd. of formula (f) and its salts:A = CCl, CF or COMe.
Patent NO-902686-L (NO)
Inventor: CHRISTENSEN JAN ARTHUR
IPC: B63B15/00
Filed: 1990-06-15
Abstract: PCT No. PCT/NO91/00086 Sec. 371 Date Feb. 8, 1993 Sec. 102(e) Date Feb. 8, 1993 PCT Filed Jun. 17, 1991 PCT Pub. No. WO91/19641 PCT Pub. Date Dec. 26, 1991.A system for maintaining the hull of a sailing boat in a steady position substantially independent of wind pressures on the sail, comprising a pivoted mast and wires connecting the mast with a weight in the boat hull via a transmission device. Transverse pivoting movement of the mast causes lateral displacement of the weight thereby maintaining the hull in a stable condition.
Patent NO-913149-L (NO)
Inventor: KOTA GEORGE M
IPC: B01D53/34
Filed: 1991-08-13
Abstract: Noxious flue gases issuing from a combustion process are treated by a chemical - mechanical process wherein initial condensation of at least a portion of the water vapour present, and intimate mixing of this condensation with a high concentration of alkali and/or alkali salts and the residual gases, results in scrubbing of the flue gases. A major portion of the resulting product is removed from the residual flue gas. The loss in thermal energy of the flue gases in the initial stage of scrubbing may be subsequently compensated by supplementary heating. Additional treatment includes the spraying of a basic substance such as limewash in dispersed relation into the residual flue gases, to eliminate the acidic content of the gases, and to regulate the amount of carbon dioxide in the atmosphere.
Patent NO-930396-L (NO)
Title: Uv-detekterbart flammehindrende middel
Inventor: BUMPUS PATRICK D
IPC: C09K21/00
Filed: 1993-02-04
Abstract: Et flammehindrende eller brannhlndrende preparat kan anvendes med fiberformige materialer inneholdende enten cellulosefibrer, ikke-absorberende fibrer eller blandinger derav. Preparatet fremstilles av en vandig oppløsning av ammoniumsulfat, et metasilikatsalt som tjener som et bindemiddel, og ammonltimfosfat (MAP eller DÅP). En ultrafiolett inhibitor innbefattes fortrinns- vis i oppløsningen. Et fuktemiddel fremmer penetrer- ingen av oppløsningen l cellulosefibrer. Et ultrafio- lett fluorescerende middel tillater ikke-destruktiv undersøkelse av gjenstander etter behandling. For forøket følsomhet er det foretrukne fluorescerende middelet et substituert 2,2'-disulfonsyrenatriurasalt.
Patent NO-942227-L (NO)
Inventor: CHEE WONG KING
IPC: A43B21/28
Filed: 1994-06-14
Abstract: Improved sports footwear comprising an insert positioned at least in the heel region, the insert comprising an elastically deformable cellular structure arranged within an elastically deformable air-impermeable casing provided with inner projections on opposing faces, the casing being pneumatically connected to controllable means, rigid with the footwear, for varying the air pressure within the casing so as to modify the elastic characteristics of the insert, each projection on one face being connected to a projection on the other face. <IMAGE>
Patent NO-950201-L (NO)
Title: Hybrid oligonukleotidfosfortioater
Inventor: METELEV VALERI
IPC: C07H21/00
Filed: 1995-01-19
Abstract: Hybride oligonukleotider med fosforotioat eller fosforoditioat internukleotidblndinger, og både deoksyribonukleosider og ribonukleosider eller 2'-substltuerte ribonukleosider er beskrevet. Slike hybride oligonukleosider har overlegende egenskaper når det gjelder dupleksdannelse med RNA, nuklease resistens og RNase H aktivering.
Patent NO-951822-L (NO)
Inventor: COHEN IRUN ROBERT
IPC: A61K31/70
Filed: 1995-05-09
Abstract: Substances comprising a N-sulfated or N-acetylated or non-sulfated N-acetylated 4-deoxy-4-en-iduronoglucosamine in substantially purified form, including compositions containing same and their uses are disclosed for the regulation of cytokine activity in a host. For instance, the secretion of Tumor Necrosis Factor Alpha (TNF- alpha ) can be either inhibited or augmented selectively by administration to the host of effective amounts of substances or their compositions comprising specific oligosaccharides in substantially purified form, in relation to the treatment or prevention of a medical condition which is selected from the group consisting of insulin-dependent diabetes mellitus, periodontal disease, inflammatory bowel disease, skin diseases, uveitis, rheumatic diseases, chronic inflammation, multiple sclerosis, lupus erythematosus, atherosclerosis, arthritis, vasculitis, allergy and neoplasia. The invention also relates to the initiation of a desirable immune system-related response by the host to the presence of activators, including pathogens, including viral infection, bacterial infection or fungal infection. <IMAGE>
Patent NO-952685-L (NO)
Inventor: LEUDOLPH JURGEN
IPC: C25C7/02
Filed: 1995-07-06
Abstract: PCT No. PCT/CH94/00217 Sec. 371 Date Nov. 13, 1995 Sec. 102(e) Date Nov. 13, 1995 PCT Filed Nov. 8, 1994 PCT Pub. No. WO95/13408 PCT Pub. Date May 18, 1995A device for the electrolytic separation of metals in a metal recovery cell has a rotating cathode system. The rotating cathode includes a supporting cylinder with at least one slit, at least one sheathed cathode, contact elements, and a drive shaft provided with a current supply. The device allows simple manipulation of the supporting cylinder with the sheathed cathode and allows the user to choose the choice of material for the sheathed cathode, since this material can be matched as closely as possible to the particular process in question. The process may be used for extracting metals from electrically conductive, metal-containing solutions for recycling purposes.
Patent NO-960334-L (NO)
Inventor: EDENBAUM MARTIN
IPC: A61F13/04
Filed: 1996-01-26
Abstract: A warp-knit casting bandage fabric is provided which comprises a first group of a plurality of individual continuous multifilament fiberglass yarns which form lengthwise extending chains of spaced-apart loops and a second group of a plurality of individual continuous multifilament fiberglass yarns which are separately interspersed with a plurality of individual continuous thermoplastic yarns forming a widthwise extending and lengthwise spaced-apart inlay which is interlaced with the spaced-apart loops forming an open-knit construction wherein the continuous thermoplastic yarns comprise from about 50% to about 100% of the total number of individual yarns forming the inlay. An elongated, resin-impregnated bandage, having a leading edge and a trailing edge, made from the warp-knit casting bandage fabric is also provided as well as a method for forming such resin-impregnated bandages.
Patent NO-981370-L (NO)
Inventor: YULE ANDREW J
IPC: A61M11/06
Filed: 1998-03-26
Abstract: PCT No. PCT/EP96/04153 Sec. 371 Date Mar. 26, 1998 Sec. 102(e) Date Mar. 26, 1998 PCT Filed Sep. 24, 1996 PCT Pub. No. WO97/11783 PCT Pub. Date Apr. 3, 1997An atomising nozzle assembly and a method for generating a respirable spray of droplets of a size suitable for medical inhalation therapy from a liquid medicament. The nozzle assembly comprises a gas nozzle (2) for producing a jet of gas and a liquid nozzle (3) for ejecting the liquid to be atomised into the jet of gas at a position downstream of the gas nozzle (2). The gas nozzle (2) and the liquid nozzle (3) are configured such that the jet of gas impinges on the liquid at an acute angle to atomise the liquid. The nozzle assembly and method can create a respirable spray using a gas/liquid mass ratio of less than 0.5.
Patent NO-982376-L (NO)
Title: Overspenningsbeskyttelsesplugg
Inventor: BUSSE RALF-DIETER
IPC: H01H37/76
Filed: 1998-05-26
Abstract: Overspenningsbeskyttelsesplugg innbefattende i det minste en spenningsbegrensende komponent med tilordnede smelteelement og en feilsikring (6). Smelteelementet utløser termisk overoppvarming av feilsikringen (6). Innretningen er valgvis utvidbar med en optisk feilsikrings-signalisering, idet den spenningsbegrensende komponenten med tilordnet smelteelement og feilsikring (6) er anordnet som lukket enhet på en første lederplate (3), som valgvis er tilordnbar den på en separat andre lederplate (10) anordnede optiske feilsikrings-signalisering.
Patent NO-983578-L (NO)
Inventor: MOSER KARL
IPC: B27D1/04
Filed: 1998-08-04
Abstract: PCT No. PCT/EP97/00546 Sec. 371 Date Aug. 4, 1998 Sec. 102(e) Date Aug. 4, 1998 PCT Filed Feb. 6, 1997 PCT Pub. No. WO97/28961 PCT Pub. Date Aug. 14, 1997The invention proposes a lamellar wood panel (1) comprising stacked, flatly superposed wood layers (3) cemented to each other at pairwise adjacent large faces (15), part of the wood layers (3) having mutually transverse fiber direction, part of the large surfaces (15) being fitted with a plurality of slots whereby the slots of the adjacent large surfaces (15) are mutually crossing, at least in part, pairwise adjacent wood layers (3) having mutually transverse fiber directions. The invention also proposes a method for manufacturing a lamellar wood panel (1) in which wood layers (3) are stacked together and cemented to each other, at least part of the wood layers (3) with mutually transverse fiber directions being stacked, slots being fitted in part of the wood-layer large surfaces (15), the wood layers (3) being stacked, and the wood stack being moved into a tightly sealable enclosure which is evacuated during at least part of the cement setting period.
Patent NO-984123-L (NO)
Inventor: TAMURA NORIKAZU
IPC: C07D403/10
Filed: 1998-09-07
Abstract: A pharmaceutical composition comprising 
(+)-1-(cyclohexyloxycarbonyloxy)ethyl 
2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H -benzimidazole-7-carboxylate, 
2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H -benzimidazole-7-carboxylic acid, 
2-ethoxy-1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)bi phenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid, 
or a salt thereof, in combination with at least one species selected from the group consisting of: 
- 2,4-oxazolidinedione derivative or a salt thereof; 
- valiolamine derivative or a salt thereof and acarbose or a salt thereof; 
- indane derivative; 
- N-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-N-(indan-2-yl)glycine or a salt thereof; and 
- (+)-3R,5S-erythro-(E)-7-[4-(4-fluorophenyl)-2,6-diisopropyl-5-methoxymethylpyridin-3-yl]-3,5-dihydroxyhept -6-enoic acid or a salt thereof.
Patent NO-984719-L (NO)
Inventor: LYKKE KIRSTEN
IPC: C08J7/048
Filed: 1998-10-09
Abstract: PCT No. PCT/DK97/00149 Sec. 371 Date Oct. 8, 1998 Sec. 102(e) Date Oct. 8, 1998 PCT Filed Apr. 8, 1997 PCT Pub. No. WO97/38853 PCT Pub. Date Oct. 23, 1997A multilayered packaging material, in particular for flexible packagings, comprising when seen from the outer face to the inner face an outer, substantially transparent film (1) having a reverse print (2) on its inwardly facing surface; an intermediate layer (3, 4) connected to the printed surface of the outer film (1) and applied in fluid form to the inner, printed surface of the outer film (1); a metallization layer (5) connected to the inner face of the gas barrier layer (3) and an inner sealing medium layer (7), preferably in form of a polyolefine.
Patent NO-994485-L (NO)
Title: Styrt frigivelse av farmasöytiske midler i det fremre kammer i öyet
Inventor: GALIN MILES A
IPC: A61K31/46
Filed: 1999-09-16
Abstract: Styrt frigivelse av farmasøytiske midler i det fremre kammer i øyet Oppfinnelsen vedrører preparater som opprettholder den strukturelle integritet av det fremre øyekammer under oftalmologisk kirurgi og som derved beskytter vevene som danner og kler det fremre segment fra eventuell skade og som samtidig tilveiebringer forsinket frigivelse av farmasøytika, inkluderende miosemidler, mydriasismidler eller anestetiske midler.
Patent NO-994919-L (NO)
Inventor: AMEDIO JOHN C
IPC: C07F9/09
Filed: 1999-10-08
Abstract: A process for preparing a phosphodiester of the formula: is described that involves (1) reaction of a first alcohol with phosphorous trichloride to form a phosphorodichlorodite, (2) reaction of the phosphorodichlorodite with an amine to form a phosphorodiamidite, (3) reaction with a second alcohol (which may be the same as the first alcohol) to form a phosphoramidite diester, and finally, (4) hydrolysis and oxidation of the phosphoramidite to form the phosphodiester. R and R1 may represent aliphatic, aromatic, heterocyclic, peptidic, peptoid, deoxyribo- or ribonucleotidic or nucleosidic, or organic chelating moieties.