baber/WOPTO huggingface dataset:
Patent WO-2019236884-A1 (WO)
Title: Inhibitors of sarm1
Inventor: HUGHES ROBERT OWEN
IPC: C07D259/00
Filed: 2019-06-06
Abstract: The present disclosure provides compounds and methods useful for inhibiting SARM1 and/or treating and/or preventing axonal degeneration.
Patent WO-2019241034-A1 (WO)
Title: Providing query recommendations
Inventor: ALONSO OMAR ROGELIO
IPC: G06F16/9032
Filed: 2019-06-07
Abstract: Examples are disclosed that relate to grouping query clusters based on intent of a search query. One example provides a method for generating recommended queries related to a search query, the method performed by a system including a logic subsystem, and memory holding instructions executable by the logic subsystem to receive the search query, execute the search query on an index of pre-computed query clusters to identify a baseline query cluster and one or more neighboring query clusters, form a data structure including queries from within the baseline query cluster and the one or more neighboring query clusters, traverse the data structure to form a hierarchical arrangement of queries, and send the hierarchical arrangement of queries to a computing device from which the search query was received.
Patent WO-2019246118-A1 (WO)
Inventor: KLEBBA PHILLIP E
IPC: C12N1/20
Filed: 2019-06-18
Abstract: A universal bacterial assay and kit for detecting and monitoring changes in concentration of a target analyte in solution. The assay relies on an engineered high affinity protein-based sensor with a detectable label that has high specificity to a target analyte, typically a ligand or metallated complex, and can be used to spectroscopically monitor interaction of the target analyte with a test bacterial strain. The sensors can be in the form of living, transport-deficient bacterial cells expressing the engineered high affinity protein, or in the form of purified proteins themselves. The system can further be used to screen candidate compounds for interference with the binding and uptake of such analytes by bacterial cells, which is useful in investigation of new classes of antibiotics.
Patent WO-2020006508-A1 (WO)
Title: Overpowered aba receptor agonists
Inventor: CUTLER SEAN R
IPC: A61K31/4439
Filed: 2019-06-28
Abstract: The present invention sets forth small novel abscisic acid (ABA) receptor agonist scaffolds and compounds with potent in vivo activity. In some aspects, the present invention provides agricultural formulations and methods comprising the ABA receptor agonists described herein, such as methods of managing crop water use and improving stress tolerance (e.g., drought tolerance). In some preferred embodiments, the inventive compounds have improved properties relative to the current "best in-class" molecules quinabactin and its derivatives.
Patent WO-2020018954-A1 (WO)
Title: Methods and systems for oral microbiome analysis
Inventor: BIGDELI SOHEIL
IPC: C12N1/20
Filed: 2019-07-19
Abstract: Described are platforms, systems, and methods for providing a recommendation for an individual regarding oral health based on an analysis of an oral biological sample from the individual. In one aspect, a method includes receiving a plurality of sequence reads of an oral biological sample collected from an individual, wherein each of the sequence reads corresponding to one or more nucleic acid molecules from at least one food source or at least one microorganism; determining an abundance by: taxonomically classifying the sequence reads to identify the at least one food source or the at least one microorganism; and quantifying the one or more nucleic acid molecules; processing the abundance through a machine learning algorithm to determine an indicator of an oral or gum disease in the individual; and providing, to a user interface, a recommendation for the individual regarding oral health.
Patent WO-2020040944-A1 (WO)
Title: Advanced nox reduction catalysts
Inventor: LI YUEJIN
IPC: B01J37/03
Filed: 2019-07-30
Abstract: A selective catalytic reduction (SCR) catalyst composition effective in the abatement of nitrogen oxides (NO x ) is provided. The SCR catalyst composition significantly increases the conversion of NO x  relative to a Cu-chabazite reference catalyst composition at any temperature, and especially at low temperatures. A catalyst article, an exhaust gas treatment system, and a method of treating an exhaust gas stream, each including the SCR catalyst composition of the invention, are also provided. The SCR catalyst composition is particularly useful for treatment of exhaust from a lean-burn engine.
Patent WO-2020033594-A1 (WO)
Title: Interpretable deep machine learning for clinical radiology
Inventor: DUNCAN JAMES S
IPC: G01N33/574
Filed: 2019-08-07
Abstract: One aspect of the invention provides a computer-implemented method of identifying one or more clinical factors associated with an artificial intelligence prediction. The computer implemented method includes: applying a previously trained deep neural network to one or more images for a subject to produce a prediction, the previously trained deep neural network comprising a plurality of nodes; comparing outputs of the nodes to previously identified patterns of node outputs for a plurality of individual clinical factors; and identifying which of the plurality of individual clinical factors are most correlated with the outputs of the nodes.
Patent WO-2020061441-A1 (WO)
Title: Suppression d'allergie ige-médiée par désensibilisation avec anticorps monoclonal anti-fc monovalent
Inventor: FINKELMAN FRED
IPC: A61P37/08
Filed: 2019-09-20
Abstract: L'invention concerne un anticorps monoclonal monovalent, l'anticorps comprenant une chaîne légère, une chaîne lourde, et une chaîne lourde tronquée, la chaîne lourde tronquée étant dépourvue d'un domaine variable et d'un domaine CH1 et l'anticorps se liant spécifiquement à un épitope de FcεRIα. L'invention concerne également des procédés de désensibilisation d'un sujet à un allergène, des procédés de traitement d'une allergie, et des procédés de prévention d'une réaction allergique chez un sujet ayant une allergie.
Patent WO-2020061586-A1 (WO)
Inventor: SMITH ADAM
IPC: G06F9/44
Filed: 2019-09-23
Abstract: A system and method may provide assistance to programmers during programming to reduce the number of routine tasks that must be performed. In some aspects, the system may suggest one or more code snippets that comprise code completions. The code snippets may be single or multi-token. In some aspects, the system may provide predictive editing or predictive navigation, where the system may predict edits or navigation actions based on a programmer's actions. In some aspects, the system is based on machine learning methods and is trained on past actions of programmers in a code editor.
Patent WO-2020069178-A1 (WO)
Title: Color stable preservative composition
Inventor: SANGIRARDI ANGELA
IPC: A01N25/02
Filed: 2019-09-26
Abstract: Provided herein is a disclosure that blending a dicarboxylic acid with a ketonic acid, used as a preservative in a end-use formulation, such as a personal care product, can mitigate the discoloration of the end-use formulation which is caused by an elevated pH in the end-use formulation or in end-use formulations which have been exposed to elevated temperature.
Patent WO-2020106365-A1 (WO)
Title: Fracture pressure transmission test apparatus with flowback module
Inventor: EVERHARD IAN LEE
IPC: E21B49/00
Filed: 2019-09-27
Abstract: In a fracture pressure transmission test apparatus utilizing fracture simulating slotted discs, the apparatus can assess the effectiveness of a lost circulation material (LCM) in a test fluid, allow for the assessment of the ability of the LCM to reduce pressure transmission to a tip of a fracture to prevent fracture propagation, and allow for the simulation of flow back to assess the ease of clean-up for reservoir applications.
Patent WO-2020073023-A1 (WO)
Title: Near-field audio rendering
Inventor: AUDFRAY REMI SAMUEL
IPC: H04S7/00
Filed: 2019-10-04
Abstract: According to an example method, a source location corresponding to an audio signal is identified. An acoustic axis corresponding to the audio signal is determined. For each of a respective left and right ear of the user, an angle between the acoustic axis and the respective ear is determined, a virtual speaker position is determined which is collinear with the source location and with a position of the respective ear, the virtual speaker position located on the surface of a sphere concentric with the user's head, the sphere having a first radius. A head-related transfer function (HRTF) corresponding to the virtual speaker position and to the respective ear is determined; a source radiation filter is determined based on the determined angle; the audio signal is processed to generate an output audio signal for the respective ear; and the output audio signal is presented to the respective ear of the user via one or more speakers associated with the wearable head device.
Patent WO-2020086692-A1 (WO)
Inventor: ATAEI ABTIN
IPC: G02B3/14
Filed: 2019-10-23
Abstract: An example system includes a bulk steering crystal apparatus having a first lens face and a second concave face. The example bulk steering crystal apparatus further includes a number of steering portions interposed between the first lens face and the second concave face, where each of the steering portions includes a bulk substrate portion including an electro-optical material and a corresponding high-side electrode electrically coupled to the corresponding one of the number of steering portions.
Patent WO-2020092544-A1 (WO)
Title: User interface and front end application automatic generation
Inventor: JASKOT TREVOR D
IPC: G06F8/33
Filed: 2019-10-30
Abstract: A method for generating a user interface for facilitating user interaction with a software application is provided. The method includes identifying an application; displaying, to a user, a list of selectable features; receiving user selections from the list; and automatically generating a user interface based on the identified application and the received user selections. As a result of the automatic generation of the user interface, command logic is generated and integrated into the user interface, thereby providing the user with an integration platform to be further connected with a database, back-end system, or network.
Patent WO-2020097034-A1 (WO)
Inventor: JANSMA MICHAEL KEVIN
IPC: H05K7/14
Filed: 2019-11-05
Abstract: L'invention concerne une unité de distribution d'énergie (PDU) qui comprend un boîtier, une pluralité de prises de courant disposées à l'intérieur du boîtier, et un élément d'éclairage dynamique pouvant fonctionner dans une couleur sélectionnée par l'utilisateur parmi une pluralité de couleurs distinctes. L'invention concerne également des systèmes et des procédés de codage couleur de chemins d'alimentation d'entrée menant à des unités de distribution d'énergie. Les unités de distribution d'énergie sont utilisées universellement dans différentes combinaisons à codage couleur avec des efficacités de fabrication et de chaîne d'approvisionnement accrues, et un traitement de commandes de clients simplifié.
Patent WO-2020097068-A1 (WO)
Title: Compositions and methods for opioid antagonist delivery
Inventor: HUANG HAIYONG
IPC: A61K9/00
Filed: 2019-11-05
Abstract: Disclosed in certain embodiments is a pharmaceutical formulation (e.g., parenteral formulation) comprising a therapeutically effective amount of nalmefene or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable adjuvant (e.g., parenterally acceptable adjuvant) that promotes the rate at which the nalmefene or salt thereof is more rapidly absorbed into the systemic circulation of a subject identified as in need thereof.
Patent WO-2020256769-A1 (WO)
Inventor: QIN YI
IPC: G02B30/24
Filed: 2019-12-04
Abstract: A head mounted display (HMD) provides multiple fields of view of a single micro-display [210] by time-multiplexing the provision of light of different polarizations. The HMD includes a micro-display, a lightguide [211], and a plurality of combiners coupled to the lightguide [214, 216], wherein each combiner is configured to combine light of a different polarization. For example, the HMD can include two combiners, with one combiner configured to combine P-polarized light and the other combiner configured to combine S-polarized light. A polarizer switch [212] is included in a filter stack for the lightguide, and a control module [630] controls the switch to alternate the provision of light having P-polarization and S-polarization, respectively. The light of each polarization provides a different field of view of the micro-display.
Patent WO-2020142745-A1 (WO)
Title: Methods of treating graft versus host disease and neoplastic disease with amide compounds
Inventor: WANG TONG
IPC: A61K31/166
Filed: 2020-01-03
Abstract: The invention relates to treatment of graft versus host disease (GVHD) or neoplastic disease using compounds that inhibit Rho-associated protein kinases. In preferred aspects, the present invention provides methods for the treatment of chronic GVHD (cGVHD) or ITD- FLT3 
 +  acute myeloid leukemia (AML) using compounds as set forth herein.
Patent WO-2020146413-A1 (WO)
Inventor: BABICH MICHAEL
IPC: C07K16/40
Filed: 2020-01-07
Abstract: L'invention concerne des constructions comprenant un fragment d'anticorps qui se lie spécifiquement à la labyrinthine ou à une partie de celle-ci et un domaine effecteur. L'invention concerne également des procédés de fabrication et d'utilisation de ces constructions et de ces compositions.
Patent WO-2020146698-A1 (WO)
Title: Systems and methods for enhanced host classification
Inventor: REVERTE CARLOS
IPC: G06F16/958
Filed: 2020-01-10
Abstract: Certain aspects and features of the present disclosure relate to systems and methods for automatically classifying hosts in real-time. For instance, classifying hosts as bots, and subsequently mitigating or blocking traffic from the hosts classified as bots can be advantageous in real-time data exchange systems. In a real-time data exchange system, data can be exchanged between a server and a target host in real-time when the target host accesses a webpage. Inhibiting data communication between servers and hosts operated by bot scripts can reduce fraudulent activity. In some implementations, hosts can be automatically classified into various groups based at least in part on the data included in requests received from the hosts.
Patent WO-2020163450-A1 (WO)
Title: Outil électrique à bornier partagé
Inventor: BRAULT RICHARD
IPC: H01M50/204
Filed: 2020-02-05
Abstract: Outil électrique, donné à titre d'exemple, comprenant une partie réceptrice d'une batterie comprenant un compartiment de batterie comportant une structure de support de batterie conçue pour recevoir et supporter une batterie comprenant des bornes de batterie. L'outil électrique comprend en outre un bornier situé dans la partie réceptrice de la batterie et comprenant des bornes d'outil. Au moins deux bornes des bornes d'outil sont conçues pour se coupler électriquement et physiquement aux bornes de batterie. L'outil électrique comprend en outre un compartiment de dispositif insérable situé dans la partie réceptrice de la batterie et conçu pour recevoir un dispositif de communication sans fil insérable comportant un premier processeur électronique, un émetteur-récepteur et des bornes de dispositif. Au moins une borne de dispositif est conçue pour se coupler électriquement et physiquement à au moins une borne partagée des au moins deux bornes des bornes d'outil. Le dispositif de communication sans fil insérable est conçu pour communiquer sans fil avec un dispositif externe.
Patent WO-2020167981-A1 (WO)
Title: Methods for increasing growth in pediatric subjects having cholestatic liver disease
Inventor: JAECKLIN THOMAS
IPC: A61K38/10
Filed: 2020-02-12
Abstract: Provided herein are methods for increasing growth in a pediatric subject having a cholestatic liver disease. The method includes administering to the subject an effective amount of an ASBTI.
Patent WO-2020168012-A1 (WO)
Title: Open cell foam metal heat exchanger
Inventor: BENSON MARK
IPC: F28D9/00
Filed: 2020-02-12
Abstract: A method of enhancing an open celled foam metal heat exchanger is presented where the structure uses fluid channels that distribute fluid and/or air across a continuous flow field. The heat exchanger not only improves heat transfer properties given a required pressure drop but also takes into consideration the need to manufacture low cost solutions that may be mass produced to meet high capacity throughput requirements for the air and space industries.
Patent WO-2020222899-A1 (WO)
Inventor: VENUGOPAL KIRAN
IPC: H04B7/06
Filed: 2020-02-28
Abstract: Certain aspects of the present disclosure provide techniques for control channel resource grouping and spatial relation configuration. Aspects of the present disclosure provide a method of wireless communication by a user equipment (UE). The method generally includes receiving an indication of one or more groupings of one or more control channel resources within a configured bandwidth. Each grouping is associated with a spatial relation. The UE applies a spatial relation for a control channel transmission using one or more control channel resources in a grouping of the one or more groupings. The grouping is associated with the spatial relation.
Patent WO-2020191107-A1 (WO)
Title: Transferring connections in a multiple deployment database
Inventor: ROBINSON ERIC
IPC: G06F16/00
Filed: 2020-03-18
Abstract: Systems, methods, and devices for transitioning a client connection for a database from a first deployment of the database to a second deployment of the database. A method includes maintaining the client connection between a client and the first deployment such that database traffic occurs at the first deployment. The method includes generating a unique identification that references a first connection object of the first deployment and a second connection object of a second deployment. The method includes receiving a notification that the first deployment is unavailable and providing an external connection group unique identification to the second deployment for the second deployment to determine whether the client should be connected to the second deployment. The method includes receiving a uniform resource locator from the second deployment if the client should be connected to the second deployment.
Patent WO-2020210552-A1 (WO)
Inventor: OKA YUKI
IPC: C12N15/09
Filed: 2020-04-09
Abstract: Disclosed herein include methods and compositions for incorporating an effector gene into the genome of a cell. The method can comprise introducing into a cell a donor nucleic acid comprising a recognition site, a splice acceptor site, a self-cleaving peptide sequence, an effector gene, and an optional transcript stabilization element. The donor nucleic acid can be incorporated into the intron of a target gene differentially expressed in a unique cell type and/or in a cell during a unique cell state via non- homologous end joining (NHEJ)-dependent DNA repair. There are also provided, in some embodiments, methods and compositions for treating a disease or disorder in a subject.
Patent WO-2020214496-A1 (WO)
Inventor: BRIMIJOIN WILLIAM
IPC: H04S7/00
Filed: 2020-04-10
Abstract: A system for generating individualized HRTFs that are customized to a user of a headset. The system includes a server and an audio system. The server determines the individualized HRTFs based in part on acoustic features data (e.g., image data, anthropometric features, etc.) of the user and a template HRTF. The server provides the individualized HRTFs to the audio system. The audio system presents spatialized audio content to the user using the individualized HRTFs.
Patent WO-2020227498-A1 (WO)
Inventor: MOYER ERIC S
IPC: B24B37/24
Filed: 2020-05-07
Abstract: A chemical mechanical polishing (CMP) pad includes a polishing portion formed using a vat-based additive manufacturing process. The polishing portion includes a polymer material with a first elastic modulus. In some embodiments the polishing portion is disposed on the backing portion. The backing portion may have a second elastic modulus. The second elastic modulus may be less than the first elastic modulus.
Patent WO-2020232158-A1 (WO)
Inventor: VASIREDDY PRAVEEN
IPC: H04L29/06
Filed: 2020-05-13
Abstract: Systems and methods for securely storing data for efficient access by cloud-based computing instances is provided. In one or more examples, a computing hub can receive one or more access requests to data stored within a persistent data storage computing resources that in connected to the computing hub. The computing hub can be configured to determine if the access request is from an authorized computing resource, and can then generate one or more tokens that provide access to the computing resource. The one or more tokens can include information regarding the IP address of the requesting cloud-based computing resource, and each time that the cloud-based computing resource uses the token to request access to the stored data, the computing hub can check the IP address of the computing resource against the IP address indicated on the token to decide whether or not to grant access to the data.
Patent WO-2020243086-A1 (WO)
Inventor: GRAHAM MARTIN EVAN
IPC: H02G15/10
Filed: 2020-05-26
Abstract: A quick disconnect system 10 for an accessory 12 electrically coupled to a component 14 of an amusement attraction includes a multi-part electrical enclosure 18 including a first side, a second side opposite the first side, a first opening on the first side, and a relief pass through 20. The multi-part electrical enclosure 18 is configured to: have a first electrical cable 16 coupled to the accessory pass 12 into the multi-part electrical enclosure 18 via the first opening 58 and have a second electrical cable 24 pass into the second side of the multi-part electrical enclosure 18 to enable the first and second cables 16, 24 to be coupled together within the multi- part electrical enclosure 18. The relief pass through 20 is configured to provide strain relief to both the first electrical cable 16 and the second electrical cable 20 and to prevent disconnection of the accessory 12 from the multi-part electrical enclosure 18.
Patent WO-2020243403-A1 (WO)
Inventor: SHU KELIU
IPC: H03M1/66
Filed: 2020-05-29
Abstract: A circuit (100) includes a phase-locked loop (110) having a phase-locked loop output to provide a first phase signal and a second phase signal phase delayed with respect to the first phase signal. The circuit (100) further includes a digital circuit (101) having a digital circuit input and an output. The digital circuit input couples to the phase-locked loop output. On the digital circuit output, the digital circuit (101) is configured to provide a first digital -to-analog converter (DAC) enable signal and a second DAC enable signal. The circuit (100) also includes first and second DACs (IDACO- IDAC3). The first DAC (IDAC0-IDAC3) is coupled to the digital circuit (101). The first DAC (IDAC0-IDAC3) has a first enable input coupled to the digital circuit output to receive the first DAC enable signal. The second DAC (IDAC0-IDAC3) is coupled to the digital circuit (101). The second DAC (IDAC0-IDAC3) has a second enable input coupled to the digital circuit output to receive the second DAC enable signal.