baber/WOPTO huggingface dataset:
Patent KR-20080037531-A (KR)
Title: Electrode for fuel cell, membrane-electrode assembly for fuel cell comprising same, and fuel cell system comprising same
Inventor: SON IN HYUK
IPC: H01M8/04
Filed: 2007-10-23
Abstract: An electrode for a fuel cell, a membrane electrode assembly containing the electrode, and a fuel cell system containing the membrane electrode assembly are provided to improve output power by using an additive having high electron and hydrogen ion conductivity. An electrode for a fuel cell comprises an electrode substrate; and a catalyst layer which is formed on the electrode substrate and comprises an active catalyst and a heteropolyvalent acid additive supported on an inorganic support. Preferably the additive has an average diameter of 1 nm to 100 micrometers and its content is 0.1-5 wt% of based on the total weight of the catalyst layer; and the inorganic support is selected from the group consisting of SiO2, zeolite and alumina.
Patent KR-20090047674-A (KR)
Inventor: SONG SA KWANG
IPC: A61B5/00
Filed: 2007-11-08
Abstract: 본 발명은 무구속 및 무자각의 수면 질 관리 장치에 관한 것으로서, 사용자의 존재 및 움직임에 따른 압력을 감지하는 다수의 압력센서들을 구비하는 무게 센서부; 사용자의 주변 수면 환경을 감지하는 다중 센서를 구비하는 환경 센서부; 및 상기 무게 센서부 및 상기 환경 센서부에서 감지된 정보들을 수집 및 분석하고, 분석된 정보들을 수면의 질에 따라 분류 및 관리하는 제어부를 포함하는 것을 특징으로 하며, 이로써 사용자의 수면 환경을 변경해 가며 학습을 통해 피측정자에 적합한 최적화된 수면 환경을 제공할 수 있으며, 편안하고 안락한 수면을 통한 피로의 회복 및 웰빙을 제공하여 낮 동안의 생활에 활력과 효율성을 제공할 수 있다.  
       
       
     수면 질 관리, 다중 센서, 압력값, 다중 센서 정보, 부가 정보.
Patent KR-20080045618-A (KR)
Title: Immersion exposure apparatus
Inventor: EMOTO KEIJI
IPC: H01L21/027
Filed: 2007-11-09
Abstract: An immersion exposure apparatus is provided to shorten moving distance of an immersion region after exposure operation, since a delivery portion is arranged near the last exposure shot region, and to suppress reaction between a resist and liquid which may occur exposure defects by considerably reducing a contact region in which the immersion region makes contact with a surface of a wafer when the immersion region moves right after the exposure operation. An immersion exposure apparatus(1) comprises a projection optical system(30), a stage(25), and a liquid supplying unit(100). The stage is configured to move a substrate(40) mounted thereon, comprising a delivery portion(43) for moving an region that makes contact with the liquid from the stage to another member, and a receiving portion(42) for receiving the region from the another member, and one or more reference marks installed on the stage for positioning the stage and a reticle. The delivery portion is installed on opposite side to one of the reference marks measured before exposure operation, with respect to a first straight line passing through a center of the substrate and perpendicular to a scanning direction. The receiving portion is installed on the same side with one of the reference marks measured after receiving the area, with respect to the first straight line. The liquid supply unit supplies liquid in a confined region between the projection optical system and stage, and recovers the supplied liquid.
Patent KR-20090050813-A (KR)
Inventor: KIM DONG GUN
IPC: G06Q50/10
Filed: 2007-11-16
Abstract: 본 발명은 게임화면 공유 멀티플레이 게임 시스템 및 그 방법에 관한 것으로서, 보다 상세하게는 자신의 게임화면에 타 유저의 게임화면이 표시되고, 상기 타 유저의 게임화면에는 상기 자신의 게임화면이 표시되는 게임화면 공유 멀티플레이 게임 시스템 및 그 방법에 관한 것이다. 
     본 발명에 따르면, 자신의 게임화면은 타 유저의 게임화면에, 타 유저의 게임화면은 자신의 게임화면에 동시에 표시할 수 있어, 게임의 재미는 물론 유저들 간의 협력 플레이를 극대화시킬 수 있는 유니크한 게임 커뮤니케이션을 제공할 수 있다. 
       
     온라인 게임, 화면, 공유, 렌더링, 스크린 샷, 대신 조작
Patent KR-20090051328-A (KR)
Inventor: LEE BUM JIN
IPC: H05B37/02
Filed: 2007-11-19
Abstract: 본 발명에 의한 다이오드를 가지는 스위치는 화장실 혹은 다용도실과 같이 전등 스위치의 온오프(on off) 상태를 외부에서 확인 할 수 없는 곳에 부착하여 동작하는 스위치로서 일반 전등을 온오프(on off) 하는 스위치와 동일하나 동작 상태를 표현하는 발광다이오드를 부착하여 스위치의 동작 여부를 발광다이오드의 점멸 또는 소등으로 표현하기 때문에 외부에서 쉽게 동작여부를 판단하여 사용하지 않을 때 전등 스위치가 온(on) 되어 있을 경우 전등스위치를 오프(off) 시켜서 절전의 효과를 얻을 수 있는 장치이지만, 도 1 와 같은 제너다이오드(14)의 반도체 특성으로 인한 파괴현상, 도 2 과 같은 부하전등의 전류에 따라서 전압의 불균형을 방지하기 위해서, 도 3 과같이 전원에 직렬로 다이오드를 다수 연결하고 다이오드에서 생기는 전압강하(212)를 이용해서 안정된 전압을 정류회로(213)에서 정류하고 점멸회로(214)에서 발광다이오드를 점멸 시켜서 전등부하 스위치가 온(on) 상태로 되어 있다는 것을 디스플레이 하는 장치이다. 
       
     제너다이오드, 점멸회로, 발광다이오드, 정류회로, 정전압회로, 다이오드 전압강하회로,
Patent KR-20090053549-A (KR)
Inventor: PAEK HO SUN
IPC: H01L33/12
Filed: 2007-11-23
Abstract: 질화물 반도체 발광소자의 제조 방법이 개시된다. 본 질화물 반도체 발광소자의 제조 방법은, m면 사파이어 기판을 질화 처리하는 단계, m면 사파이어 기판 상에 고온 완충층을 형성하는 단계, 고온 완충층 상에 반극성 (11-22)면 질화물계 박막을 형성하는 단계, 및, 반극성 (11-22)면 질화물계 박막 상에 제1 질화물 반도체층, 활성층 및 제2 질화물 반도체층을 포함하는 발광구조물을 형성하는 단계를 포함한다. 이에 따라, m면 사파이어 기판을 적정 온도 범위에서 질화 처리함으로써, m면 사파이어 기판 상에 형성되는 반극성 (11-22)면 질화물계 박막의 결정성을 향상시킬 수 있다.   
       
     발광소자, m면 사파이어 기판, 반극성, (11-22)면, 질화 처리
Patent KR-20090054689-A (KR)
Title: System and method for controlling air conditioner for a vehicle
Inventor: RYU CHANG GI
IPC: B60H1/32
Filed: 2007-11-27
Abstract: A car air-conditioner control system and a control method thereof are provided to reduce the exhaust gas while preventing the output degradation. A car air-conditioner control system comprises a navigation(30) and a controller(50). The navigation receives the altitude information of the road in regular intervals. The controller calculates the altitude difference of the time point according to the altitude information and calculates the gradient factor of the road using the above. The controller continually compares the gradient factor and standard value. A compressor(70) is turn off if the gradient factor is higher than the standard value. The compressor is turned on if the gradient factor is lower than the standard value.
Patent KR-20090057846-A (KR)
Title: Apparatus and method for broadcasting on mobile terminal
Inventor: YANG JIN YOUNG
IPC: H04B7/26
Filed: 2007-12-03
Abstract: A broadcast output device and a method thereof using a mobile terminal and a broadcasting receiver are provided to allow a user to watch broadcasting program through a broadcasting receiving device such as television. An input unit(130) receives a key input from the outside. A near field communications module(114) transmits and receives wireless signal according to a local communications system. If the prescribed key is inputted through the input unit, a controller detects the channel information with reference to the service ID of the broadcasting system. The controller transmits the channel information with the external device through the local area communications module. The local communications system is one among an IrDA(Infrared Data Association), Bluetooth, an RFID(Radio Frequency ID) and ZigBee.
Patent KR-20090060063-A (KR)
Title: Spin-valve magnetoresistive element with perpendicular magnetic anisotropy
Inventor: JOO HO WAN
IPC: H01L21/8247
Filed: 2007-12-07
Abstract: A spin valve magnetoresistive device is provided to lower a coercive force of a free layer by forming the free layer and a fixed layer by Pd layer/ferromagnetic layer or ferromagnetic layer/Pd layer. A free layer and a fixed layer are formed by repetitively depositing Pd layer/first ferromagnetic layer. An antiferromagnetic layer is positioned between the free layer and the fixed layer. The first ferromagnetic layer has a vertically magnetized structure on the Pd layer. The free layer is formed between a buffer layer formed on a predetermined substrate and the antiferromagnetic layer. The Pd layer/first ferromagnetic layer of N number is formed on a top part of the buffer layer. A Pd layer and a second ferromagnetic layer are successively formed between the first ferromagnetic layer and the antiferromagnetic layer. The second ferromagnetic layer is formed between the antiferromagnetic layer and the Pd layer/first ferromagnetic layer.
Patent KR-20090061144-A (KR)
Title: Method of measuring flow velocity by ultrasonic waves and method of measuring flux by ultrasonic waves
Inventor: HWANG SHANG YOON
IPC: G01F1/66
Filed: 2007-12-11
Abstract: A flow rate measuring method and a flux measuring method using ultrasonic waves are provided to measure the flow rate of fluid passing through the peripheral region of a fluid pipe without installation of additional ultrasonic flowmeter circuit. A flow rate measuring method using ultrasonic waves comprises a step of preparing ultrasonic flowmeter circuits separated from each other(M101), a step of measuring the flow rate of fluid passing through the line connecting ultrasonic oscillators(M102), a step of measuring the flow rate of fluid passing through the area surrounded with an outermost ultrasonic flowmeter line and the inner wall of a fluid pipe in which the ultrasonic wave is reflected(M103), and a step of setting the measured flow rate as a flow rate of the fluid passing through the straight line parallel with the outermost ultrasonic flowmeter line(M104).
Patent KR-20090062052-A (KR)
Inventor: LEE CHUNG MAN
IPC: A47B65/00
Filed: 2007-12-12
Abstract: 이 책꽂이는 현재에 나온 책꽂이에 비해 부피를 축소시킬수가 있어 이동및 설치 그리고 사용하지 않을때에 보관 할수 있는 것이다. 
       
     길이 연장 , 하중, 힌지
Patent KR-20090063288-A (KR)
Title: Latte art pattern shaper
Inventor: YUN JAE WOONG
IPC: A47J31/00
Filed: 2007-12-14
Abstract: A latte art pattern shaper is provided to easily and quickly form the latte art pattern and approach the latte art. A latter art pattern shaper comprises an ingredient can(100), opening and closing unit(200), and patterning unit(300). An inlet port and outlet port are formed in the ingredient can. The opening and closing part discharges the ingredients downward through the outlet port. The patterning unit is combined to the outlet of ingredient can. The patterning unit is drilled to discharge the ingredients downward.
Patent KR-20090063863-A (KR)
Title: Structure of oil-inflow and oil-pressure check
Inventor: KIM KYOUNG SOO
IPC: F16H57/02
Filed: 2007-12-14
Abstract: An oil pressure detection structure of a center support is provided to check correctly internal oil pressure of the center support and to reduce restrictions of a circuit composition of a valve body by inserting a check plug into oil pressure detection holes of connective parts. An oil pressure detection structure of a center support(20) includes an inlet hole and an oil pressure detection unit(30). The inlet hole is extended to an overlapped part between a valve body and the center support. The oil is transferred from the outside to the inside of the center support. The oil pressure detection unit is installed at the overlapped part between the valve body and the center support in order to check the oil pressure of the inside of the center support. The oil pressure detection unit includes a first oil pressure detection hole(32) extended to the inside and the outside of the center support, a second oil pressure detection hole(34) extended to the first oil pressure detection hole, and a check plug(36) for checking the oil pressure of the inside of the center support.
Patent KR-20090067630-A (KR)
Title: Nanopowder using a rf plasma combustion and method of manufacturing thereof
Inventor: PARK JONG IL
IPC: B82B3/00
Filed: 2007-12-21
Abstract: Nano-powder and a manufacturing method thereof using RF plasma combustion are provided to supply proper heat energy to a precursor by placing a powder spraying nozzle 0.1-3cm away from a center of an induction coil. A method for manufacturing nano-powder comprises the following steps of: preparing magnesium oxide(MgO) powder and metal oxide powder with 10-100mum of diameter(201); mixing the prepared powder mechanically to obtain mixed powder(203); injecting the mixed powder together with powder injecting gas into an RF(Radio Frequency) plasma combustion device; supplying shielding gas in the RF plasma combustion device(213); and supplying quenching gas in the RF plasma combustion device(215).
Patent KR-20090069971-A (KR)
Title: Opticalpipe system
Inventor: LEE HWAN HEE
IPC: G02B6/00
Filed: 2007-12-26
Abstract: Alight pipe system is provided to reduce assembly process time by installing a first fixing part and a second fixing part inside a sleeve, and offer excellent luminance and emission of the light to various directions. A light pipe system(100) includes a light pipe. The light pipe includes a sleeve and an optical film. The sleeve includes a first fixing part and a second fixing part. The optical film(130) is located in a sleeve inner surface. The optical film is located between the first fixing part and the second fixing part. A length ratio of a cross section of the optical film and a reflection part is 1 : 1.
Patent KR-20070039031-A (KR)
Inventor: HAITSMA JAAP
IPC: G06F12/00
Filed: 2005-07-04
Abstract: 본 발명은 하나 초과의 메모리 디바이스를 구비하는 메모리 시스템에 데이터 파일을 분배하는 방법에 대한 것이다. 각각의 메모리 디바이스는 적어도 하나의 데이터 파일을 저장하기 위해 배열된다. 이 방법의 단계는 각 메모리 디바이스로의 데이터 기록 속도를 나타내는 속도 지시자를 획득하는 단계(S1); 획득된 속도 지시자에 따라 분배 시나리오를 정하는 단계(S2); 및 정해진 분배 시나리오에 따라 데이터 파일을 메모리 디바이스에 분배하는 단계(S3)를 포함한다.
Patent KR-20070031416-A (KR)
IPC: C04B35/10
Filed: 2005-07-19
Abstract: 미세 분획 및 조제 분획을 갖는 금속 산화물 분말을 함유하는 수성 분산액으로서, - 상기 금속 산화물 분말은 이산화규소, 산화알루미늄, 이산화티타늄, 이산화지르코늄, 산화세륨, 또는 상기 언급한 금속 산화물 중 2 이상의 혼합 산화물이고, - 상기 미세 분획은 응집된 형태로 존재하며, 분산액 내에서 200 nm 미만의 평균 응집체 직경을 갖고, - 상기 조제 분획은 1 내지 20 ㎛의 평균 직경을 갖는 입자로 이루어지고, - 미세 분획 대 조제 분획의 비율은 2:98 내지 30:70이고, - 금속 산화물 분말의 함량은 분산액 총량에 대해 50 내지 85 중량%임을 특징으로 하는 수성 분산액.  상기 수성 분산액은 - 200 KJ/m 3  이상의 에너지를 인입하여 임의로 pH-조절 및(또는) 계면활성 첨가제를 함유하는 물에 분말 미세 분획을 분산시켜, 미세 분획 분산액 중의 미세 분획의 함량이 30 내지 60 중량%인 미세 분획 분산액을 제조하는 단계; - 저에너지 인입에서의 분산 조건하에, 미세 분획 및 조제 분획의 총 함량이 50 내지 85 중량%가 되는 양으로 분말 형태의 조제 분획을 상기 미세 분획 분산액에 첨가하는 단계를 포함하는 방법으로 제조된다. 
     미세 분획, 조제 분획, 이분산액, 금속 산화물
Patent KR-20070052278-A (KR)
Inventor: MOGENSEN LASSE
IPC: A61M25/02
Filed: 2005-08-10
Abstract: 본 발명은 주사세트의 기저부를 이루는 구성부재에 적합한 캐뉼러 장치에 관한 것이다. 캐뉼러 장치는 하우징과, 커넥터의 관입부재를 수용할 수 있는 적어도 하나의 공동부를 형성하고 있는 적어도 하나의 멤브레인으로 이루어지며, 덧붙여서 캐뉼러 장치는 상기 하우징에 장착되고 상기 적어도 하나의 공동부와 상호 유체연통하는 캐뉼러를 구비하는바, 여기서 장치는 하나 이상의 방향에서 커넥터의 관입부재를 수용할 수 있고 하우징은 기하학적 형상을 갖춰 캐뉼러가 기저부에서 하나 이상의 방향으로 뻗을 수 있다.
Patent KR-20070085284-A (KR)
Title: A transmucosal veterinary composition
Inventor: HUHTTNEN MIRJA
IPC: A61P25/20
Filed: 2005-11-03
Abstract: The present invention relates to a veterinary composition in a semisolid form adapted for transmucosal administration for providing sedation and analgesia in large animals such as horses and cattle. The semisolid transmucosal composition of the invention comprises detomidine or a pharmaceutically acceptable salt thereof as an active ingredient. The composition provides a rapid onset of action while having low irritation potential in the oral mucosa.
Patent KR-20070083967-A (KR)
Title: Mecs dialyzer
Inventor: BROWNING DAVID M
IPC: B01D61/00
Filed: 2005-10-06
Abstract: The present invention is related to hemodialysis, and more particularly, to a dialyser with improved efficiency of mass transfer across a dialysis membrane utilizing microchannel separation provided in accordance with embodiments of the present invention. In accordance with an embodiment, a dialyzer is provided comprising a plurality of semipermeable membrance sheets and a plurality of flow separators. The membrane sheets and flow are arranged in alternating configuration and coupled into a laminae stack defining a plurality of parallel microchannel layers. Each microchannel layer comprises a plurality of first microchannels and a plurality of second microchannels. The first and second microchannels of each microchannel layer are in fluid communication with each other via one of the plurality of membrane sheets therebetween. The MECS dialyzer is characterized as having a high surface to volume ratio and a high mass transfer coefficient.
Patent KR-20070087569-A (KR)
Title: Application and packaging unit for mascara and use thereof for makeup
Inventor: TRANCHANT JEAN FRANCOIS
IPC: A45D40/26
Filed: 2005-11-25
Abstract: The invention relates to an applicator/packaging (1) for mascara (M), comprising a container (5, 6) with an axis (X'X) and wall (6), defining an interior space, the upper part (6b) of the wall (6) being rigid and the lower part (6a) of the wall (6) being flexible and able to be moved from an expanded position into a closed position, temporary closure means (2,3a) for said container (5, 6), a head (4), mounted on a pin (3b), fixed to the closure means (2,3a) and coming into contact with mascara (M), in the closed position. The volume of the lower part (6a) represents 15 % to 60 % of the total volume defined by the wall (6). Alternatively, the packaging and application unit (1) is embodied such that the head (4) is largely opposite said rigid part (6b), perpendicular with relation to (X'X). The above is of application to make-up.
Patent KR-20070088697-A (KR)
Title: Bandpass filter
Inventor: AKALE TAMRAT
IPC: H01P1/203
Filed: 2005-11-03
Abstract: An edge-coupled filter (20) includes a phase velocity compensation transmission line section (30) comprising a series of spaced alternating T-shaped conductor portions (32A-40A).
Patent KR-20070104364-A (KR)
Title: Electromagnetic pressure control valve device provided with an integrated pressure sensor
Inventor: FLEISCHER WALTER
IPC: G05D16/20
Filed: 2005-12-13
Abstract: The invention relates to an electromagnetic pressure control valve device which is used to control hydraulic pressure contained in at least one pressure control valve (1) comprising a magnetic part (2) which comprises at least one coil body (8) which supports an electric coil (10), a coil core (12) and a displaceable anchor (14), a valve part (4) which comprises at least one inlet connection (36), a return connection (40), a user connection (42) and a control element (46) which co-operates with the valve seat (44) and which can be actuated by the anchor (14), and an electronic part (68) which comprises at least one pressure sensor (70) which is used measure the hydraulic pressure arising on the user connection (42. According to the invention, at least the pressure sensor (70) is arranged on one end of the magnetic part (2) which is oriented towards the valve part (4) on the electronic part (68). The filter effect of the transmission path is clearly reduced by the arrangement of the pressure sensor which is close to the valve and the hydraulic pressure which is to be measured can be transmitted in an error free manner until the cut-off frequency is clearly increased. As a result, the pressure valve is measured and controlled in a more precise manner.
Patent KR-20070117615-A (KR)
Title: Novel polypeptide, polynucleotide encoding the polypeptide and use the polypeptide and polynucleotide
Inventor: HORI KANJI
IPC: C07K14/42
Filed: 2006-02-27
Abstract: Disclosed is a polypeptide capable of binding to a sugar chain, particularly a high-mannose-type sugar chain bound to an antibody, more preferably a sugar chain bound to a chicken antibody. Also disclosed is a method for the purification of an antibody (specifically a chicken antibody) as a representative application of the polypeptide. Further disclosed is means for the purification. The polypeptide, BML-17, is a novel lectin made of 168 amino acid residues isolated from Bryopsis maxima. By using BML-17, it becomes possible to purify an antibody (e.g., a chicken antibody) readily and with high efficiency.
Patent KR-20080006544-A (KR)
Title: Loudspeaker
Inventor: DODD MARK
IPC: H04R7/12
Filed: 2006-03-02
Abstract: A loudspeaker comprises a horn waveguide having a waveguide surface, and a transducer located in, or adjacent to, a throat of the horn waveguide. The transducer has a substantially rigid convex dome-shaped acoustically radiating surface. A horn angle subtended between a longitudinal axis of the horn waveguide and the waveguide surface at the throat of the horn, is in the range 20 to 60 degrees. An intersection angle subtended between a plane tangential to the dome shape of the acoustically radiating surface and a plane tangential to the waveguide surface at a point where the dome shape or an extrapolation of the dome shape meets the waveguide surface or an extrapolation of the waveguide surface, is in the range 85 to 110 degrees.
Patent KR-20080017304-A (KR)
Title: Online computation of market equilibrium price
Inventor: JAIN KAMAL
IPC: G06Q30/00
Filed: 2006-05-19
Abstract: Auction prices for a quantity of items, the quantity of which is not determined prior to auction, are equilibrated among bidders to reflect supply and demand for the items. For example, in auctioning Internet advertising opportunities, the first available opportunities are auctioned to a high bidder. Later in the course of the auction period, once the high bidder's budget has been exhausted, the price for advertising opportunities is reduced. The difference in price paid by the high bidder and the reduced price for the quantity of advertising opportunities purchased is credited to the high bidder's account. Once the high bidder's account regains a level sufficient to acquire additional advertising opportunities, the high bidder may continue to acquire advertising opportunities. Other bidders similarly are credited the difference between prices previously paid and the current price. An equilibrium price is reached based on the recursive adjustment of prices paid by the bidders.
Patent KR-20080020987-A (KR)
Title: Method and arrangement for supplying power to several induction coils in an induction apparatus
Inventor: HAAG THOMAS
IPC: H05B6/44
Filed: 2006-05-02
Abstract: The aim of the invention is to operate induction coils (L1, L2) of an induction cooking hob (11) with as little noise as possible. Said aim is achieved by operating the induction coils (L1, L2) at the same frequency fg (mode of operation a) or at a frequency difference Deltaf of about 18 kHz (mode of operation c), especially during alternating operation. Changing back and forth between said modes of operation makes it possible to reach predefined values (P1, P2) for the power of the induction coils (L1, L2) at the mean-time value while disturbing noise is prevented from developing. ® KIPO & WIPO 2008
Patent KR-20070119091-A (KR)
Title: Column-parallel sigma-delta analog-to-digital conversion for imagers
Inventor: BOEMLER CHRISTIAN
IPC: H04N5/363
Filed: 2006-04-12
Abstract: A sigma-delta modulation sensing circuit and an analog-to-digital converter for an imager that do not rely on the ratio of the reset and pixel voltage levels being sensed. The sensing circuit includes a regulation branch (273) based on a reference voltage common across multiple columns of the imager. The regulation branch has an adjustable resistance switched capacitor circuit) that is modulated during the sensing operation, which creates an adjustment current that is applied during the sensing operation to a current associated with one of the reset and pixel signals. The sensing circuit and analog-to-digital converter can generate a digital code based on the difference between the reset and pixel signal voltage levels, which substantially mitigates noise associated with the pixel and reset signal voltages. The reference voltage can also be used as a gain control for the imager as well.
Patent KR-20080036547-A (KR)
Title: Production of recombinant proteins by autoproteolytic cleavage of a fusion protein
Inventor: JUNGBAUER ALOIS
IPC: C12N9/50
Filed: 2006-04-25
Abstract: Disclosed is a method for the production of a heterologous polypeptide of interest with a homogenous N-terminus, using a fusion polypeptide comprising the polypeptide of interest and N-terminally thereto a polypeptide exhibiting autoproteolytic function, said method comprising the steps of a) binding of the fusion polypeptide in a soluble, autoproteolytically inactive form by an affinity chromatography system, b) refolding of the fusion polypeptide, thereby activating the autoproteolytic function of the fusion polypeptide and causing cleavage of the heterologous polypeptide of interest, and c) subsequently eluting the heterologous polypeptide of interest, wherein said steps are conducted on one affinity chromatography system.