baber/WOPTO huggingface dataset:
Patent AU-770633-B2 (AU)
Title: Improved chemical process and pharmaceutical formulation
Inventor: ERICKSON MAGNUS
IPC: A61P1/04
Filed: 1999-11-15
Granted: 2004-02-26
Abstract: Process for the manufacturing of slightly soluble or less soluble alkaline salts of substituted sulphinyl heterocycles containing an imidazole moiety with formula Ipreferably alkaline salts of a proton pump inhibitor compound, wherein the process comprises the step of reacting the substituted sulphinyl heterocycle of Formula I with a source of the cation in the presence of a base, characterized by a washing step in which the prepared alkaline salt of the substituted sulphinyl compound is washed with a basic aqueous solvent mixture. The obtained bulk drug substance resulting in a bulk product that in an aqueous suspension of the substituted sulphinyl heterocycle having a pH not significantly lower than that of a saturated water solution of the pure compound prepared. Alternatively, the process for manufacturing a pharmaceutical dosage form comprising the active substance could be adjusted. For instance the pH of an aqueous suspension of the active substance is adjusted to a pH not significantly lower than that of a saturated water solution of the pure compound. The processes are preferably useful in the manufacturing of omeprazole magnesium salt or magnesium salt of one of its single enantiomers used in pharmaceutical dosage forms.
Patent AU-679627-B2 (AU)
Title: An improved method of synthesis for 6,9-bis((2-aminoethyl)amino)benzo(g)isoquinoline-5,10-dione and its dimaleate salt
Inventor: SPINELLI SILVANO
IPC: A61K31/473
Filed: 1995-03-27
Granted: 1997-07-03
Abstract: In the search for novel heteroanalogs of anthracendiones, 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione dimaleate salt (BBR 2778), was selected as the most promising compound. New methods of synthesis produce the compound in purity greater than 99%.
Patent AU-666859-B2 (AU)
Title: Novel compositions based on taxane class derivatives
Inventor: BASTART JEAN-PIERRE
IPC: A61K47/44
Filed: 1992-07-03
Granted: 1996-02-29
Abstract: The invention relates to new compositions based on derivatives of the taxane class, consisting of solutions of these derivatives in a solvent mixture composed of ethanol and polysorbate. These solutions are used to prepare perfusions.
Patent AU-782169-B2 (AU)
Title: A process for converting storage reserves of dicot seeds into compositions comprising one or more gene products
Inventor: KOIVU KIMMO
IPC: C12N15/82
Filed: 2000-12-08
Granted: 2005-07-07
Abstract: The present invention is related to a process based on a source-sink principle, for producing products of interest from crushed or uncrushed germinating dicot seeds comprising an expression system, which is induced or can be induced during germination. The product is either a seed derived composition comprising one or more gene products. Alternatively, it is a product of interest obtained by placing the composition in contact with a substrate, containing a substance capable of being transformed by the seed derived composition as such, dried or in down-stream processed form.
Patent AU-766336-B2 (AU)
Title: Identifying, monitoring, and treating women for breast precancer or cancer
Inventor: LOVE SUSAN
IPC: C12Q1/68
Filed: 2000-01-25
Granted: 2003-10-16
Abstract: The invention provides devices, kits and methods for delivering an agent to a breast milk duct. Intraductal agent delivery provides an opportunity to treat a breast condition locally and avoid the pitfalls of systemic drug delivery for a local condition. Time-released agents delivered into the ducts using an intraductal device or formulation reduces the frequency of intraductal administration required for desired efficacy over time. The methods include methods of treating a breast condition, including the conditions of cancer or precancer.
Patent AU-611751-B2 (AU)
Title: Hydrophilic colored contact lenses
Inventor: NARDUCY KENNETH W
IPC: C08J7/043
Filed: 1988-11-21
Granted: 1991-06-20
Abstract: There is disclosed a method for making colored hydrophilic contact lenses. A contact lens constructed of hydrophilic polymer that is substantially devoid of the functional groups -COOH, -OH, -NH-R, wherein R is hydrogen or C1 to C8 alkyl, -NCO and epoxy is provided. At least a portion of the surface of the lens is coated with a color coat comprising at least one pigment, binding polymer having functional groups selected from at least one of -COOH, -OH, and -NH-R, wherein R is hydrogen or C1 to C8 alkyl, and an additional compound having at least two groups per molecule of -NCO. The coated lens is subjected to conditions which cause the color coat to adhere to the lens.
Patent AU-764295-B2 (AU)
Title: Aluminium alloy containing magnesium and silicon
Inventor: TUNDAL ULF
IPC: C22F1/05
Filed: 1999-02-12
Granted: 2003-08-14
Abstract: An ageing process capable of producing an aluminum alloy with better mechanical properties than possible with traditional ageing procedures. The ageing process employs a dual rate heating technique that comprises a first stage in which the aluminum alloy is heated at a first heating rate to a temperature between 100 and 170° C. and a second stage in which the aluminum alloy is heated at a second heating rate to a hold temperature of 160 to 220° C. The first heating rate is at least 100° C./hour and the second heating rate is 5 to 50° C./hour. The entire ageing process is performed in a time of 3 to 24 hours.
Patent AU-662190-B2 (AU)
Title: Slow burning alcohol-free nitrocellulose
Inventor: KHANSHAB AKBER ALI
IPC: C08L1/18
Filed: 1992-12-18
Granted: 1995-08-24
Abstract: An alcohol-free and encapsulated nitrocellulose which is primarily suitable for printing inks, varnishes and coatings consists of 65-75% nitrocellulose, 3-8% water, 10-15% non-solvating plasticizer and 10-15% of an active solvent suitable for both nitrocellulose and the plasticizer. A product is produced by drying water-wet nitrocellulose and spraying on a solution of plasticizer in solvent. Upon blending to a uniform consistency, the nitrocellulose becomes partially dissolved and encapsulated within the plasticizer/solvent mixture. The advantages of the invention are improved safety indicated by a lower rate of burning and reduced environmental pollution wherein the product is alcohol-free such that no additional alcohol recovery system is required.
Patent AU-564069-B2 (AU)
Title: 1,4-dihydropyridine derivatives containing mmono-or di-saccharide substitutents
Inventor: HEIKER FRED ROBERT
IPC: C07H15/26
Filed: 1984-07-20
Granted: 1987-07-30
Abstract: Novel 1,4-dihydropyridines of the fomula   <IMAGE>   in which R1 and R2 each independently is hydrogen, C1-C4-alkyl, C1-C12-alkoxy, C1-C4-halogenoalkoxy, halogen, nitro, C1-C4-halogenoalkyl, C1-C4-halogenoalkylmercapto,   <IMAGE>  in which Z is oxygen or sulphur, and R4 and R5 each independently is hydrogen, C1-C4-alkyl, C1-C6-alkoxy, halogen, C1-C4-halogenoalkyl, C1-C4-halogenoalkoxy or nitro, or R1 and R2, together with 2 C atoms of the phenyl ring, form the ring   <IMAGE>   X is oxygen, sulphur or the radical NR6, R6 is a C1-C6-alkyl group, A is a C2-C10-alkylene group, it being necessary that at least two C atoms are located in the alkylene chain which connects the carbonyloxy group to X, and R3 is a monosaccharide or disaccharide moiety or a protected monosaccharide or disaccharide moiety, or pharmaceutically acceptable addition salts thereof, which exhibit positive inotropic activity and are useful in treating circulatory disorders.
Patent AU-630085-B2 (AU)
Title: 4,5,6,7-tetrahydro isothiazolo (4,5-c) pyridine derivatives
Inventor: KROGSGAARD-LARSEN POVL
IPC: A61K31/425
Filed: 1989-03-14
Granted: 1992-10-22
Abstract: Novel compounds of the formula: <CHEM>  wherein R<1>, R<2>, R<3> and R<4> are as defined in Claim 1, as well as individual isomers and pharmaceutically acceptable acid addition salts are described as having acetylcholine agonistic activity making them useful in the treatment of diseases of the brain, e.g. Alzheimer's disease. Methods for the preparation of the novel compounds are also described, as well as pharmaceutical compositions containing same.
Patent AU-568048-B2 (AU)
Title: Grinding a transverse element for a driving belt
Inventor: JK JOHANNES ABRAHAM VAN DI
IPC: B24B19/26
Filed: 1984-09-26
Granted: 1987-12-10
Abstract: The invention relates to a process for machining a flat transverse element for a driving belt, which element is provided with an edge that can come into contact with an endless carrier of the driving belt and is curved in the direction of movement of the belt and in a direction perpendicular thereto. The process is carried out by grinding a flat transverse element with a cylinder having a concave outer surface provided with abrasive material on its outside, with which the edge to be ground is brought into contact and by performing a relative rocking movement of element and cylinder. The invention also relates to apparatus for conducting the process.
Patent AU-625536-B2 (AU)
Title: Communication processor for a packet-switched network
Inventor: MAKRIS PERRY
IPC: H04L12/56
Filed: 1989-03-30
Granted: 1992-07-16
Abstract: A packet switch receives data and processes it for assembly into packages. A bus allows communication between each of the data processing units of the switch and one or more storage units for storing the data packets. Arbitration for deciding which of the processing units will be granted access to the bus is performed by a system which selectively and alterably designates any of at least two different levels of priority of access to the bus for each of the processing units, and the relative percentages of time of access for the different priorty levels. The system assures greater access to the bus by those of the processing units having the higher level of priority. If communication is provided by two buses, the requests for access are alternated between them. The arbitration system provides selective access to the bus in any of a plurality of bus cycles including a read cycle, a write cycle and a read/modify/write cycle, and grants a request for access from a higher priority processing unit within one bus cycle.
Patent AU-675784-B2 (AU)
Title: Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
Inventor: GRISAR J MARTIN
IPC: A61P1/04
Filed: 1993-03-12
Granted: 1997-02-20
Abstract: This invention relates to novel hydrazide acyl hydrazinium derivatives of certain 3,4-dihydro-2H-1-benzopyrans of formula (1), the stereoisomers and mixtures thereof, their inner salts, and the pharmaceutically acceptable salts thereof wherein R is H or C1-6 alkyl, R1 is C1-6 alkyl, R2 is H or -C(O)R, R3 and R4 are independently C1-6 alkyl; R5 is C1-6 alkyl, or (a) with R8 being H or halogeno, n is zero, 1, 2, or 3 and X is a halide, -S(O)3R6, or nothing when the inner salt is formed, R6 is H, C1-6 alkyl, phenyl or 4-methylphenyl, to the intermediates, processes and techniques for their preparation, to their ability to manifest the property of being free radical scavengers, and to their end-use application in the treatment of disease conditions capable of being ameliorated by free radical scavengers.
Patent AU-658061-B2 (AU)
Title: Novel cross-linked water-absorbent resin
Inventor: CHIANG WILLIAM G-J
IPC: C08F20/22
Filed: 1993-05-07
Granted: 1995-03-30
Abstract: This invention is directed to a recurring polymeric moiety of the following formula: <CHEM> wherein R is independently selected from hydrogen and C1 to C4 alkyl; Y is independently selected from O and NH; and X is independently selected from Cl, F, Br, I, NO3, HSO4 and H2PO4. Polymers of the above structure may be crosslinked by treating the polymer with a base and heating it.
Patent AU-629845-B2 (AU)
Title: Detection and amplification of target nucleic acid sequences
Inventor: LAFFLER THOMAS G
IPC: G01N33/53
Filed: 1989-08-28
Granted: 1992-10-15
Abstract: A method and kits for amplifying and detecting target nucleic acid sequences in a sample is disclosed. the method employs primers which have reactive pair members linked to them. The reactive pair members can be attached to a solid phase and/or detected by labeled conjugate.
Patent AU-618437-B2 (AU)
Title: Modular knee prosthesis
Inventor: SLAMIN JOHN EDWARD
IPC: A61F2/00
Filed: 1989-12-21
Granted: 1991-12-19
Abstract: A knee prothesis system which is composed of a femoral component and a series of bolts capable of being attached to the femoral component and extending through the femoral component at different angles. These angles correspond to different valgus angles. The system also includes stems of different lengths which can be attached to the bolts to provide a system with stems of different lengths set at different valgus angles.
Patent AU-578304-B2 (AU)
Title: Apparatus for detecting a movement of a digital television signal
Inventor: KONDO TETSUJIRO
IPC: H04N5/14
Filed: 1985-09-06
Granted: 1988-10-20
Abstract: Upon execution of the movement detection by way of a gradient method the leftward and rightward sampling differences AEL and AER at a change extremal value point are used to detect the respective movements in the vertical and horizontal directions. The movement amounts detected are selectively fetched. Upon addition/subtraction of the frame difference, the sign of sample is held until the positive or negative sign of the sample which is obtained from the result of comparison between the sampling difference values before and after the sample is changed. The accurate movement detection is performed by controlling the addition/subtraction in response to the holding signal.
Patent AU-622507-B2 (AU)
Title: Absorbable coating and blend
Inventor: OLSON JAMES R
IPC: A61K47/34
Filed: 1989-12-28
Granted: 1992-04-09
Abstract: Absorbable coating and absorbable blend of polycaprolactone and crystallization modifier especially suitable for use in the coating of surgical sutures and in the controlled release of chemical or pharmaceutical agents.
Patent AU-584643-B2 (AU)
Title: Fabric finishing composition and process of imparting fabric finish to textile materials
Inventor: REICHLEY FRED J
IPC: D06M15/263
Filed: 1985-10-11
Granted: 1989-06-01
Abstract: An aqueous fabric finishing composition includes a solubilized polymer of from 40 to 51 mole percent of a mixture of higher one-alkenes and from 60 to 49 mole percent maleic anhydride.
Patent AU-581939-B2 (AU)
Title: Diastereoselective reduction of 3-amino -1-benzoxepine -5(2h)-one
Inventor: OHLENDORF HEINRICH WILHELM
IPC: C07D313/08
Filed: 1985-11-04
Granted: 1989-03-09
Abstract: A process for producing cis-2,3,4,5-tetrahydro-3-amino-1-benzoxepin-5-ols in which 3-amino-1-benzoxepin-5(2H)-ones are diastereoselectively reduced in a single stage by catalytic hydrogenation in the presence of a platinum oxide catalyst and an equivalent amount of an acid in a polar protic solvent, or by reaction with a borane/amine complex in an aprotic solvent, optionally in the presence of an added lower aliphatic carboxylic acid.
Patent AU-729061-B2 (AU)
Title: Method of increasing fat firmness and improving meat quality in animals
Inventor: COOK MARK E
IPC: A23K1/18
Filed: 1997-10-20
Granted: 2001-01-25
Abstract: A method of treating meat animals to increase fat firmness and meat quality indices which increases meat processability consists of administering to the meat animals a safe and effective amount of conjugated linoleic acid or CLA.
Patent AU-668599-B2 (AU)
Title: Filling machine
Inventor: WADELL LARS GUSTAF ALBERT
IPC: B65B3/30
Filed: 1993-11-10
Granted: 1996-05-09
Abstract: A machine and process for filling a product (13) volumetrically which comprises introducing the product into a hopper (12), recording the level of the product (13) in the hopper (12) and transmitting the recorded information to a computer (18), conveying an empty chamber (19) to a position beneath the hopper (12), automatically adjusting the volume of the empty chamber (19) and filling the empty chamber (19) with the product (13) conveying the filling chamber (19) away from the hopper (12) and discharging the product (13), recording the weight of the discharged product (13) and transmitting the recorded weight to the computer (18), the automatic adjustment of the volume of the empty chamber (19) being based on the recorded imformation transmitted to the computer (18). <IMAGE>
Patent AU-773204-B2 (AU)
Title: Compositions of CPG and saponin adjuvants and methods thereof
Inventor: KENSIL CHARLOTTE A
IPC: A61K39/39
Filed: 1999-08-06
Granted: 2004-05-20
Abstract: Vaccine compositions of immunostimulatory oligonucleotides and saponin adjuvants and antigens and the use thereof for stimulating immunity, enhancing cell-mediated immunity, and enhancing antibody production are disclosed. Also described are immune adjuvant compositions comprising immunostimulatory oligonucleotides and saponin adjuvants, as well as methods for increasing an immune response using the same.
Patent AU-644793-B2 (AU)
Title: Method and apparatus for iontophoretic drug delivery
Inventor: LAPRADE RONALD E
IPC: A61N1/30
Filed: 1990-05-30
Granted: 1993-12-23
Abstract: An iontophoretic device for delivery of a drug comprising a flexible, non-conductive backing; first and second conductive electrodes composed of a substantially non-ionizing material in a plane, one side of the plane which is optionally attached to the optionally flexible backing, and the other side of the plane which is adapted to be affixed to one side of a flexible and electrically conductive layer containing the drug to be delivered; a source of electrical current and a device for reversing the polarity of the two electrodes. The device can additionally include the conductive layer containing the drug to be delivered, affixed to the plane of the two electrodes. An ion exchange membrane can optionally be disposed between the two electrodes and the drug-containing layer. The device can optionally contain a pulsing device or a current varying device or both to vary the amount of current delivered from time to time or in absolute amount.
Patent AU-622339-B2 (AU)
Title: Method and reagent for the determination of antithrombin iii
Inventor: DESSAUER ANDREAS
IPC: C12Q1/56
Filed: 1990-07-11
Granted: 1992-04-02
Abstract: To determine antithrombin III in body fluids by reacting the sample with thrombin and a chromogenic substrate which produces a colour on exposure to thrombin, and measuring the resulting colour, the reaction is carried out in the presence of denaturing agents or of the tetrapeptide Gly-Pro-Arg-Pro, and the substrate used is an oligopeptide whose sensitivity is a factor of 5 to 100 less than that of Tos-Gly-Pro-Arg-pNA.
Patent AU-679717-B2 (AU)
Title: Thioxanthenone antitumor agents
Inventor: WENTLAND MARK PHILIP
IPC: C07F9/24
Filed: 1994-04-07
Granted: 1997-07-10
Abstract: Compounds having anti-tumour activity are disclosed having the formula <CHEM>       wherein: (1) n is 2 or 3;     R<1> and R<2> are independently lower-alkyl; Q is a residue chosen from the group consisting of CH2NHR<3>, CH2N(R<4>)SO2R<7>, CH2NHCHO, CH=N-Ar, C(O)NR<5>R<6>, CH2N(R<4>)C(O)R<7>, CH2N(C2H5)CHO, CH2N(R<4>)P(O)(O-lower-alkyl)2, CH2N=CH-N(R<9>)(R<10>), CH2N(R<4>)C(O)CF3 and CH2N(R<4>)C(O)OR<7>;   R<3> is hydrogen or lower-alkyl;   R<4> is hydrogen, lower-alkyl or Ar;   R<5> is hydrogen, lower-alkyl or Ar;   R<6> is hydrogen or lower-alkyl;   R<7> is lower-alkyl, or Ar;   R<8> is hydroxy; Ar is phenyl or phenyl substituted with methyl, methoxy, hydroxy, halogen or nitro; and   R<9> and R<10> are independently lower-alkyl; or   (2) Q is a residue chosen from the group consisting of CH2N(R<4>)SO2R<7>, CH=N-Ar, C(O)NR<5>R<6>, CH2N(R<4>)C(O)R<7>, CH2N(R<4>)P(O)(O-lower-alkyl)2, CH2N(R<4>)C(O)CF3 and CH2N(R<4>)C(O)OR<7>; R<8> is hydrogen, lower-alkyl, lower-alkoxy, or hydroxy; Ar is phenyl substituted by hydroxy; and n, R<1>, R<2>, R<4>, R<5>, R<6>, and R<7> are as defined hereinabove in part (1) with the proviso that one or more of R<4>, R<5>, or R<7> is Ar; or (3) Q is a residue chosen from the group consisting of CH2N=CH-N(R<9>)(R<10>) and CH2N(R<4>)C(O)CF3 ; R<8> is hydrogen, lower-alkyl, lower-alkoxy, or hydroxy; and n, R<1>, R<2>, R<4>, R<7>, Ar, R<9> and R<10> are as defined hereinabove in part (1), or a pharmaceutically acceptable acid-addition salt or solvate thereof .   Compositions containing the thioxanthenones and methods of treating tumors and cancer in mammals with the thioxanthenones are also disclosed.
Patent AU-633941-B2 (AU)
Title: Cardholders incorporating keepers
IPC: B42D15/10
Filed: 1990-07-19
Granted: 1993-02-11
Abstract: PCT No. PCT/GB90/01044 Sec. 371 Date Jul. 24, 1991 Sec. 102(e) Date Jul. 24, 1991 PCT Filed Jul. 19, 1990 PCT Pub. No. WO91/17680 PCT Pub. Date Nov. 28, 1991.In the technical field of known cardholders for devices such as cards with magnetic stripes on which is encoded information and or data in the form of patterns of magnetism, the known cardholders offer no method of 'keeping' (in magnetism terminology) the magnetic patterns. The present invention is characterised by incorporating into the cardholders, keepers in the form of sheets of magnetically soft ferromagnetic material with high resistance. The benefit of the invention is obtained when devices are placed with the reading surface of their magnetized stripes in close contact with the surface of the ferromagnetic material which, making use of known properties of the material, then acts as keeper of the magnetic patterns.
Patent AU-769041-B2 (AU)
Title: Virtual makeover
Inventor: RIGG RICHARD TYSON
IPC: G06T11/60
Filed: 2000-06-09
Granted: 2004-01-15
Abstract: A method and apparatus is provided for virtual color makeover of a customer's face. A digital image is taken of the customer's face. Natural skin color is determined by a differential analysis among at least two different sites along the face to identify an area without color. The identified area without color is then used as a basis for projecting the customer's face with the natural skin color. Consultant's choice of preprogrammed color palettes matching the measured natural skin color is then projected on the facial image. A customer's personal choice such as fashion, natural or go-to-work looks can be registered for modifying the consultant's choice color palette. The selected color palette can then be identified as a set of color cosmetic products which are provided to the customer.
Patent AU-629020-B2 (AU)
Title: New pesticide uses of bialaphos
Inventor: BENOIT MARC
IPC: A01N57/20
Filed: 1990-08-07
Granted: 1992-09-24
Abstract: A method of combatting insects comprising contacting insects with an insecticidally effective amount of L-2-amino-4-[(hydroxy) (methyl) phosphinyl]-butyryl-L-alanyl-L-alanine.
Patent AU-774865-B2 (AU)
Title: Conjugates of sodium channel blockers and methods of using the same
Inventor: BOUCHER RICHARD C JR
IPC: C07D/
Filed: 2000-07-19
Granted: 2004-07-08
Abstract: Compounds of the general formula P1-L-P2; wherein "P1" is a pyrazinoylguanidine sodium channel blocker, "L" is a linking group, and "P2" is either (i) a pyrazinoylguanidine sodium channel blocker or (ii) a P2Y2 receptor agonist, are disclosed. Pharmaceutical formulations containing the same and methods of use thereof to hydrate mucosal surfaces such as airway mucosal surfaces are also disclosed.
Patent AU-578169-B2 (AU)
Title: N-alkylation of dihydrolysergic acid
Inventor: MARZONI GIFFORD PURNELL
IPC: A61K31/48
Filed: 1986-09-29
Granted: 1988-10-13
Abstract: The present invention provides a process for preparingwherein R' is C<sub>3</sub>-C<sub>e</sub> alkyl, -CH<sub>2</sub>C<sub>2</sub>-C<sub>4</sub> alkenyl, propargyl, C<sub>3</sub>-C<sub>8</sub> cycloalkyl or C<sub>1</sub>-C<sub>6</sub> alkyl substituted C<sub>3</sub>-C<sub>8</sub> cycloalkyl; which comprises: reacting a compound of Formula (II):with a substituted benzenesulfonate of Formula III):wherein R' is as defined above and R<sup>2</sup> is hydrogen, bromo, methyl or nitro, in the presence of a base.