baber/WOPTO huggingface dataset:
Patent DE-69211342-T2 (DE)
Inventor: CHICK WILLIAM
IPC: A61F2/02
Filed: 1992-03-24
Granted: 1997-01-23
Abstract: A device which serves as an artificial pancreas comprises a hollow fiber which is surrounded by islets of Langerhans enclosed in a housing. The islets are suspended in a semi-gel matrix or supporting material that is sufficiently viscous to physically support and maintain location of the islets about the hollow fiber, but sufficiently fluid to enable removal of the islet suspension from the device, followed by reseeding or replacement with fresh islet suspension. The matrix in which the islets are suspended preferably comprises calcium sodium alginate. The semi-gel supporting material also enables long term maintenance of islet cells in in vitro culture.
Patent DE-69213768-T2 (DE)
Inventor: ANELLI PIERLUCIO
IPC: C07C237/46
Filed: 1992-12-01
Granted: 1997-01-23
Abstract: PCT No. PCT/EP92/02770 Sec. 371 Date Jun. 1, 1994 Sec. 102(e) Date Jun. 1, 1994 PCT Filed Dec. 1, 1992 PCT Pub. No. WO93/12071 PCT Pub. Date Jun. 24, 1993.    <IMAGE>  (I)  wherein R, R', R1, and R1', which are the same or different, are H, C1-C4 alkyl, linear or branched C1-C4 mono- or polyhydroxyalkyl; R2, R2', R3, and R3', which are the same or different, are one of the groups of formula -CH2CH2OH, -CH2CH(OH) CH2OH -CH(CH2OH)CH(OH)CH2OH, -CH2(CHOH)4CH2OH, or -CH(CH2OH)2; and X is one of the groups -CH(OH)-, -CH(CH2OH)-, -C(OH) (CH2OH)-, or -C(CH2OH)2-, are useful as opacifying components for X-ray contrast media.
Patent DE-69221016-T2 (DE)
Inventor: DAIGLE RONALD E
IPC: G01N29/44
Filed: 1992-04-24
Granted: 1997-11-13
Abstract: A method of position sensing using ultrasound that allows unconstrained motion of a scanhead 12,80 or sensing probe. Combined with ultrasound echo sensing, a static, B-mode ultrasound imaging system is obtained that does not require mechanical arms or similar structures. The signal acquisition means comprises a scanhead 12 having two or more ultrasound transducers 70-74, 90-94 that convert echoes from a subject into echo signals. For B-mode imaging, an image processor 32 processes the echo signals to produce intensity data for a scan line 16 having a known orientation with respect to the scanhead 12. The echo signals are Doppler processed to produce position data representing the relative positions of a series of scan lines 16, and a scan converter combines the intensity and position data to produce a two-dimensional image of the subject. The scan converter first processes samples along each scan line to produce intermediate intensity values, and then combines intermediate intensity values for adjacent scan lines to produce the output image.   <IMAGE>
Patent DE-69231546-T2 (DE)
Inventor: ISHIKAWA KIYOFUMI
IPC: C07K5/02
Filed: 1992-11-26
Granted: 2001-05-31
Abstract: A peptide derivative of the formula: <CHEM> wherein A is a group of the formula R<1><1>O-CO- (wherein R<1><1> is a lower alkyl group or a phenyl group), or a group of the formula R<1><2>R<1><3>N-C(=O)- (wherein R<1><2> is a lower alkyl group, a cycloalkyl group, a 1-adamantyl group, a phenyl group wherein one or two optional hydrogen atoms on the benzene ring may independently be replaced by a halogen atom, a trifluoromethyl group, a nitro group, an amino group or a formylamino group, a pyridyl group, or a thienyl group, R<1><3> is a hydrogen atom, a lower alkyl group or a cycloalkyl group, or R<1><2> and R<1><3> form, together with the adjacent nitrogen atom, a 5- to 9-membered nitrogen-containing saturated heterocyclic ring having 4 to 8 carbon atoms, wherein among methylene groups forming the ring, one optional methylene group not adjacent to the above nitrogen atom may be replaced by a thio group, and one to four optional hydrogen atoms on the carbon atoms of the heterocyclic ring may independently be replaced by a lower alkyl group, and further two adjacent carbon atoms in the heterocyclic ring may form a benzo-fused ring); B is an oxygen atom or a group of the formula -NR<2>- (wherein R<2> is a hydrogen atom or a lower alkyl group); R<3> is a lower alkyl group, a cycloalkyl group, an aryl group, a heterocyclic group, a cycloalkyl lower alkyl group, an aryl lower alkyl group or a heterocyclic lower alkyl group; X<1> is an oxygen atom or a group of the formula -NR<4>- (wherein R<4> is a hydrogen atom or a lower alkyl group); R<5> is a 3-indolylmethyl, 3-benzothienylmethyl, 1-naphthylmethyl or benzyl group wherein one or two optional hydrogen atoms on the ring may be replaced by a hydroxyl group, a halogen atom, a formyl group, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a lower alkylsulfinyl group, a lower alkylsulfonyl group, a lower alkoxycarbonyl group, a nitro group or a group of the formula R<5><1>-CO-X<2> {wherein R<5><1> is a lower alkyl group, a lower alkoxy group, or an amino group which may be substituted by a lower alkyl group, and X<2> is an oxygen atom or a group of the formula -NR<5><2>- (wherein R<5><2> is a hydrogen atom or a lower alkyl group)}; X<3> is an oxygen atom or a sulfur atom; R<6> is a hydrogen atom, or a lower alkyl or lower alkenyl group which may have a substituent selected from the group consisting of a hydroxyl group, a lower alkoxy group, a lower alkylthio group and a heterocyclic group; n is 0 or 1; Y is a hydroxymethyl group, a group of the formula CO2R<7><1> (wherein R<7><1> is a hydrogen atom or a lower alkyl group), a group of the formula CONHR<7><2> (wherein R<7><2> is a hydrogen atom or a lower alkyl group which may have a substituent selected from the group consisting of a hydroxyl group, a carboxyl group and a sulfo group), a 1H-tetrazol-5-yl group, a sulfo group and a phosphono group; or a pharmaceutically acceptable salt thereof.
Patent DE-69233058-T2 (DE)
Inventor: BALKOVEC JAMES M
IPC: C07K7/54
Filed: 1992-10-01
Granted: 2004-03-04
Abstract: Certain propionitrile compounds which have a cyclohexapeptidyl nucleus and which are found to have antibiotic activity with physical properties suitable for use in therapeutic compositions are described. A novel process for their preparation is also described. <CHEM> a
Patent DE-69316167-T2 (DE)
Inventor: HAJJ MOHAMED
IPC: H04B10/61
Filed: 1993-11-15
Granted: 1998-04-16
Abstract: This transmission system over an optical link, by modulation of an optical carrier, especially for a cabled video communication network, is characterised essentially in that, especially for the case of high optical transmission power, to be coupled into the said optical link, it includes means (9, 10, 11, 12, 13) for increasing, if necessary, the modulation ratio of the optical carrier, possibly from the zero value in the case in which the said modulation is modulation other than amplitude modulation, in such a way as to avoid, or to limit, the phenomena of degradation of the transmission quality relating to the Brillouin effect. <IMAGE>
Patent DE-69324250-T2 (DE)
Inventor: LARSEN THOMAS
IPC: A01N37/06
Filed: 1993-04-29
Granted: 1999-07-08
Abstract: The invention described here concerns the unique utility of fatty acids and their derivatives to act as fruit thinning agents. Proper use of the methods and compositions will result in the advantageous thinning of fruit which can improve the quality of the harvested fruit and result in more consistent crops from one year to the next.
Patent DE-69405054-T2 (DE)
Inventor: CAVAZZA CLAUDIO
IPC: C07C229/22
Filed: 1994-06-10
Granted: 1997-12-18
Abstract: The use is disclosed of esters of L-carnitine and acyl L-carnitines with hydroxyacids for producing pharmaceutical compositions suitable to be topically applied for treating dermatoses such as ichthyosis and psoriasis.
Patent DE-69409862-T2 (DE)
Inventor: STANHOPE HARRY W
IPC: F16G5/06
Filed: 1994-02-17
Granted: 1998-09-03
Abstract: In an improved power transmission belt (10), the circumferentially disposed reinforcing cords (30) are made from multi-filament yarns (32) of heterofilaments. These cords, when fused, have good inter-filament bonding without the solvent of the solvent/adhesive systems. <IMAGE>   <IMAGE>
Patent DE-69412924-T2 (DE)
Inventor: CHOQUET PATRICK
IPC: C23C16/06
Filed: 1994-06-24
Granted: 1999-02-04
Abstract: Process for coating with paint by electrophoresis of an article made of galvanised alloy steel, such as a sheet, which consists in a first step in vacuum-depositing on at least one face of the said article of galvanised alloy steel an iron-zinc coating containing less than 60 % of iron by weight and whose thickness does not exceed 1  mu m and then in subjecting the said article, thus coated, to an operation of painting by electrophoresis. This process makes it possible to avoid the phenomenon of surface crater formation on the substrate, delays the appearance of seizing and facilitates the subsequent shaping of the substrate.
Patent DE-69414709-T2 (DE)
Inventor: TARI ANA MARIA
IPC: C12N5/10
Filed: 1994-07-29
Granted: 1999-04-22
Abstract: A liposomal methyl phosphonate oligonucleotide composition useful in treatment of chronic myeloid leukemia comprises (a) a liposome which comprises at least one phospholipid, and (b) an antisense methyl phosphonate oligonucleotide which is entrapped in the liposome. The molar ratio of phospholipid in the liposome to the methyl phosphonate entrapped in the liposome is between about 100:1 and about 10,000:1. A process for making the composition includes the steps of (a) mixing an antisense methyl phosphonate oligonucleotide in a first organic solvent with at least one phospholipid in a second organic solvent, where the molar ratio of phospholipid to methyl phosphonate is between about 100:1 and about 10,000:1, (b) lyophilizing the mixture formed in step (a), producing a lyophilized powder, (c) hydrating the lyophilized powder, and (d) sonicating the hydrated material.
Patent DE-69415673-T2 (DE)
Inventor: POSCICH DOUGLAS
IPC: F16D1/04
Filed: 1994-06-29
Granted: 1999-05-20
Abstract: A coupling mechanism for quickly coupling a rotor body to its drive and driven journals and thereby obtaining radial and axial alignment thereof in a closely confined space is provided. The coupling mechanism includes a split ring collar and a clamping ring securely holding in appropriate placement a chamfered split ring for radially and axially aligning the rotor and the journals, hereinafter referred to as co-axial alignment.
Patent DE-69416859-T2 (DE)
Inventor: HARRISON BOYD
IPC: C07D335/06
Filed: 1994-11-03
Granted: 1999-08-05
Abstract: PCT No. PCT/US94/12658 Sec. 371 Date Aug. 6, 1996 Sec. 102(e) Date Aug. 6, 1996 PCT Filed Nov. 3, 1994 PCT Pub. No. WO95/14669 PCT Pub. Date Jun. 1, 1995The present invention relates to novel benzenesulfonylimine derivatives and their use as inhibitors of Interleukin-1 (IL-1) action. Such inhibitors are useful in the treatment of various disease states as disclosed herein including: rheumatoid arthritis, multiple sclerosis, diabetes mellitus, atherosclerosis, septic shock and pulmonary fibrosis.
Patent DE-69422182-T2 (DE)
Inventor: CVETOVICH RAYMOND
IPC: C07H19/01
Filed: 1994-08-15
Granted: 2000-06-21
Abstract: The most thermodynamically stable crystalline form of the benzoic acid salt of 4"-deoxy-4"-epi-methylamino avermectin B1a/B1b as the hemihydrate is obtained by crystallization from organic solvents containing a controlled amount of water.
Patent DE-69426023-T2 (DE)
Inventor: PUTTEMAN PETER
IPC: G01F11/02
Filed: 1994-06-30
Granted: 2001-05-10
Abstract: PCT No. PCT/EP94/02149 Sec. 371 Date Dec. 12, 1995 Sec. 102(e) Date Dec. 12, 1995 PCT Filed Jun. 30, 1994 PCT Pub. No. WO95/01924 PCT Pub. Date Jan. 19, 1995A childproof device (1) for holding and dispensing liquids, in particular medicines, that provides precise dosages of liquid, comprising a bottle (2), a cap (5) which is irremovable from the bottleneck (4), said cap being associated with a hollow cylinder (6) extending axially to near the bottle bottom (3) and a reciprocating dispenser comprising a barrel (8) and a plunger (9). The dispenser provides the only means of getting medicine out of the bottle since the cylinder associated with the cap prevents the contents of the bottle from being poured or shaken out. The device is easily assembled and can be stored, sold and used as supplied by the manufacturer.
Patent DE-69427300-T2 (DE)
Inventor: LINDQUIST BENGT
IPC: B31F1/07
Filed: 1994-09-08
Granted: 2001-12-06
Abstract: An absorption body (10) is disclosed which is suitable for use in e.g. sanitary napkins. The body includes at least one layer of an absorbent material and has a plurality of longitudinally extending embossed channels (12). In order to promote distribution of discharged body fluid across the absorption body, at least three channels are present, and the layer of absorbent material provides the absorption body (10) with a basis weight of between about 80 and 240 g/m<2>, preferably between about 120 and 160 g/m<2>. The body is produced from a continuous web of material which is embossed by passing the web between a pair of heated rollers. The absorption body may be a laminate of two or more layers of absorbent material and super-absorbent material may be present. <IMAGE>
Patent DE-69430122-T2 (DE)
Inventor: GROMAT JOHANNES
IPC: E04B1/10
Filed: 1994-06-17
Granted: 2002-10-31
Abstract: PCT No. PCT/AU94/00335 Sec. 371 Date Mar. 8, 1996 Sec. 102(e) Date Mar. 8, 1996 PCT Filed Jun. 17, 1994 PCT Pub. No. WO95/02097 PCT Pub. Date Jan. 19, 1995A building structure formed from transportable prefabricated panel frame section is disclosed. The building structure includes wall and/or floor and/or roof frames. Each wall frame is formed from a plurality of similar wall panel frame sections having frame side members. The wall panel frame sections are arranged in the wall frame with the frame side members of adjacent wall panel frame sections spaced apart. A joining member is located between adjacent frame side members and rigidly fastens the frame side members to one another. Each joining member extends vertically beyond the side frame members for interconnecting the side frame members therebelow to a floor frame and/or a roof frame and/or another wall frame thereabove.
Patent DE-69431596-T2 (DE)
Inventor: KUCERA LOUIS S
IPC: A61K31/70
Filed: 1994-05-25
Granted: 2003-06-26
Abstract: A method of treating hepatitis virus infection is disclosed. The method comprising administering to a human subject in need of such treatment an effective hepatitis virus-combatting amount of an alkyl lipid or alkyl lipid derivative.
Patent DE-69434041-T2 (DE)
Inventor: WARRELLOW JOHN
IPC: C07D261/12
Filed: 1994-12-21
Granted: 2005-10-06
Abstract: Compounds of general formula (1):    <IMAGE>  (1)  wherein Y is a halogen atom or a group -OR1 where R1 is an optionally substituted alkyl group; X is -O-, -S- or -N(R8)-, where R8 is a hydrogen atom or an alkyl group; R2 is an optionally substituted alkyl, alkenyl, cycloalkyl or cycloalkenyl group; R3 is a hydrogen or halogen atom or an -OR9 group, where R9 is a hydrogen atom or an optionally substituted alkyl, alkenyl, alkoxyalkyl, or alkanoyl group, or a formyl, carboxamido or thiocarboxamido group; R4 is a group -(CH2)nAr, where Ar is a monocyclic or bicyclic aryl group optionally containing one or more heteroatoms selected from oxygen, sulphur or nitrogen atoms and n is zero or an integer 1,2 or 3; R5 is a C3-9 carbocyclic ketone optionally containing one or more heteroatoms selected from oxygen, sulphur or nitrogen atoms; R6 is a hydrogen atom or an optionally substituted alkyl group; R7 is a hydrogen atom or an optionally substituted alkyl group; and the salts, solvates, hydrates and N-oxides thereof. Compounds according to the invention are potent and selective phosphodiesterase type IV inhibitors and are useful in the prophylaxis and treatment of diseases such as asthma where an unwanted inflammatory response or muscular spasm is present.
Patent DE-69501606-T2 (DE)
Inventor: RUSCHE EMIL HERMAN
IPC: B67C3/26
Filed: 1995-08-30
Granted: 1998-05-28
Abstract: An assembly for providing a passage for liquid between a first member (6) comprising a liquid reservoir such as a concentrate container or storage vessel and a second member such as a liquid outlet, the assembly comprising a first connector (2) which is adapted to be mounted on the second member and comprises piercing means (42) by means of which an opening can be provided in the first member (6), wherein the assembly further comprises a second connector (4) which is undetachably connected to the first member, while in use the first and second connectors are connected to each other and the first connector is moved relative to the second connector in such a manner that the piercing means force an opening in the first member, whereby said passage is effected. <MATH>
Patent DE-69511191-T2 (DE)
Inventor: BEAUDET JEAN-YVES
IPC: A47J43/07
Filed: 1995-08-30
Granted: 2000-03-09
Abstract: The mixer comprises a base (11) enclosing an electric motor (13) whose output shaft (15) projects from the base. A bowl (18) is mounted above the base, with a cover (20) mounted over the bowl. A rotary tool (24) is mounted in the base of the bowl in order to be coupled to the motor shaft. The cover and the upper edge of the bowl are fastened together by means of a bolt (44) which is solidly attached to the cover. Associated with the cover is a transmission element (46) operable by the bolt, passing through the handle (38) to reach a switch (50). The switch acts to prevent operation of the motor when the cover is open, whilst permitting operation once the cover is closed.
Patent DE-69531150-T2 (DE)
Inventor: BARRITAULT DENIS
IPC: A61K31/35
Filed: 1995-03-29
Granted: 2004-04-29
Abstract: PCT No. PCT/FR95/00398 Sec. 371 Date Jan. 3, 1997 Sec. 102(e) Date Jan. 3, 1997 PCT Filed Mar. 29, 1995 PCT Pub. No. WO95/26736 PCT Pub. Date Oct. 12, 1995Use of at least one polymer or one biopolymer, called HBGFPP, specifically protecting the growth factors of the FGF and beta TGF families from tryptic degradation in the manufacture of a drug for the treatment of muscular tissues.
Patent DE-69535021-T2 (DE)
Inventor: PROFFITT L
IPC: B31B19/26
Filed: 1995-06-16
Granted: 2006-11-30
Abstract: A label assembly for a package sleeve accommodating a storage media disc in a sleeve cavity thereof. The label assembly includes a removable tear strip covering the sleeve cavity such that when the tear strip is detached along perforation lines, the disc can be removed from the sleeve cavity. The tear strip also has a deadened adhesive portion so that no adhesive can contact the disc. In this label assembly, a first face and a second face are positioned on opposite sides of the tear strip. The first face includes mailing identification information regarding the package sleeve and the second face includes disc identification information regarding the storage media disc accommodated within the package sleeve.
Patent DE-69605426-T2 (DE)
Inventor: WESSELS JOHANNES
IPC: B63C11/30
Filed: 1996-08-29
Granted: 2000-07-06
Abstract: PCT No. PCT/GB96/02128 Sec. 371 Date Jul. 15, 1998 Sec. 102(e) Date Jul. 15, 1998 PCT Filed Aug. 29, 1996 PCT Pub. No. WO97/08048 PCT Pub. Date Mar. 6, 1997A diving ballast (131) is adapted to be fitted to a scuba tank, so as to replace or at least supplement a waist-fitted weightbelt. The diving ballast (131) comprises an elongate flexible strap formed with open-ended weight-receiving holsters (122) therein and a plurality of weights (126) each having expanded ends and a waisted portion (127) defined between the expanded ends. Each weight is of such dimensions in relation to a weight-receiving holster (122) so that the expanded end of the weight can be worked through the holsters so that the weighted portion is held captive within the holster. The expanded end of the weight can only be worked through the holster when the strap is slack and the waisted portion (127) is held captive by the material of the holster when the strap is under tension along its length. The diving ballast extends to a waist-fitted weightbelt of the type described, as well as to an ankle-belt having a similar configuration. The invention further extends to a diving ballast system incorporating all three types of ballast.
Patent DE-69606624-T2 (DE)
Inventor: CARIC STJEPAN
IPC: A45D26/00
Filed: 1996-11-19
Granted: 2000-09-07
Abstract: Depilation apparatus with a housing and a depilation member for gripping hairs on human skin and pulling the hairs from the skin comprises a vibration member for exerting mechanical vibrations on the skin. Such mechanical vibrations have an anaesthetizing effect on the skin so that pain sensations caused by the process of pulling hairs from the skin are relieved. The vibration member comprises flexible protrusions which have been disposed on a carrier. In this way, the mechanical vibrations are introduced into the skin in distinct concentrated positions on the skin.
Patent DE-69628352-T2 (DE)
Inventor: RAY III EDDIE F
IPC: A61B17/58
Filed: 1996-03-27
Granted: 2004-04-08
Abstract: A fusion device (10) for implantation within an intervertebral space between adjacent vertebrae. The device comprising an elongated body (11) having a length and defining external threads (18,19) along said length. The device being characterized by the external threads (18,19) being circumferentially interrupted along said length so as to define an opposing pair of threaded portions extending along said length. <IMAGE>
Patent DE-69635622-T2 (DE)
Inventor: ARECCHI TITO
IPC: B61B13/10
Filed: 1996-11-22
Granted: 2006-06-22
Abstract: The system comprises a plurality of annular guided circuits (A, B, C, D) which are independent of one another and one-way; each circuit is tangential to at least one adjacent circuit at a station (SD) with tracks side by side and an intermediate platform; each circuit also comprises further stations (S).
Patent DE-69712822-T2 (DE)
Inventor: CONGER KENNETH DEAN
IPC: B29D30/20
Filed: 1997-03-18
Granted: 2002-11-28
Abstract: A turret (22) for a tire building system having two drums (26,49) with drum shafts (30,42) mounted on the turret and adjusted so that the axes of the drums will be offset and parallel providing a compact turret assembly with a minimum shaft length and weight. The offset drum shafts provide for positioning of the drums in operating positions of different heights (50,52) relative to the floor surface (12) so that manual operations can be carried out at the lower drum position where there is easy access by an operator. Safety provisions (74) are incorporated to disengage the motor (63) and stop rotation of the turret if the motor does not stop and thereby protect the operator and the turret mechanism.
Patent DE-69719820-T2 (DE)
Inventor: VAN HALTEREN TIJMEN
IPC: E02D11/00
Filed: 1997-10-09
Granted: 2003-12-18
Abstract: A steel pile, adapted to be driven e.g. by vibration, into the ground. A fluid collecting and distributing passage (3) extends along and below at least part of the lower edge(s) of the body of the pile. The passage is supplied with fluid through a supply conduit (5) extending upwardly along the body of the pile. When driving the pile into the ground fluid is discharged from the passage through downwardly facing openings, such that the soil directly below the lower edge(s) is brought and kept in a fluidized state.
Patent DE-69720485-T2 (DE)
Inventor: HOFFMEYER PIERRE
IPC: A61F2/40
Filed: 1997-10-08
Granted: 2004-03-04
Abstract: A proximal humeral prosthesis that is particularly designed for treating a fractured humerus. The prosthesis comprises a head corresponding to the humeral head of a patient, and a stem having a proximal end to which the head is mounted. The prosthesis has a central plane coincident with the longitudinal axis of the stem about which it has a mirror axis of symmetry. One, or preferably pair of, projecting ribs are positioned at or near the proximal end of the stem adjacent the head. The projecting ribs are offset in opposite directions relative to the center plane at substantially identical offset angles (e.g., about 20 DEG  to about 40 DEG ) approximating the greater or lesser tuberosity of the humerus. Also disclosed is a method of treating a fractured humerus with this prosthesis.