baber/WOPTO huggingface dataset:
Patent CA-2664171-A1 (CA)
Inventor: CHISHOLM ROBERT SYMES
IPC: B01F29/62
Filed: 2001-02-12
Abstract: Mixing of components, e.g. pharmaceutical actives and excipients, is carried out while monitoring the spectroscopic profile of the mixture during the mixing process so that the spectroscopic profile may be used to determine the point at which mixing is terminated. In one embodiment of the invention, the spectroscopic data is collected by means of a monitoring unit mounted on the mixing vessel the mixing vessel being mounted and driven so as to rotate or oscillate mounted and thereby effect mixing of its contents and the monitoring unit being mounted for rotation or oscillation with the vessel. When the spectroscopic data indicates that mixing has progressed to a desired state, e.g. the production of a homogeneous blend, the monitoring unit transmits a signal to the drive source to terminate rotation or oscillation of the vessel.
Patent CA-2667487-A1 (CA)
Inventor: XU YONG
IPC: A61P35/00
Filed: 2007-11-06
Abstract: L'invention concerne des inhibiteurs de protéines kinases qui comprennent des composés d'imidazo[1,2-b]pyridazine et de pyrazolo[1,5-a]pyrimidine représentés par les structures (I) et (II) suivantes, ou un stéréo-isomère, un promédicament ou un sel pharmaceutiquement acceptable de ceux-ci. Dans la formule, R, R1, R2 et X sont tels que définis dans la demande. L'invention concerne aussi des compositions et des procédés d'utilisation de celles-ci dans le traitement du cancer et d'autres états pathologiques associés à une kinase Pim.
Patent CA-2671984-A1 (CA)
Title: New pyridazine derivatives with mch antagonistic activity and medicaments comprising these compounds
Inventor: TIELMANN PATRICK
IPC: C07D403/12
Filed: 2007-12-10
Abstract: The present invention relates to compounds of general formula I wherein the groups and radicals B, W, X, Y, Z, R1, R2, have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one compound according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.
Patent CA-2672022-A1 (CA)
Inventor: VAN TOL HUIBERT
IPC: B63B21/00
Filed: 2009-07-14
Abstract: A mooring assembly for a vessel comprises a receiving vessel part, a geostationary part received rotatably in said receiving vessel part and a main bearing assembly connecting the geostationary part to the receiving vessel part. The main bearing assembly comprises at least two separate bearings which are manipulable such that the one or the other or both bearings are in an operative position, thus allowing the non-operative bearing to be replaced, overhauled, repaired and alike in situ.
Patent CA-2672201-A1 (CA)
Title: Use of myb gene to diagnose and treat t-cell acute lumphoblastic leukemia
Inventor: COOLS JAN
IPC: A61K31/713
Filed: 2007-11-07
Abstract: The present invention relates to the field of biotechnological means to diagnose or treat T-cell acute lymphoblastic leukaemia. More particularly, the invention relates to methods to diagnose T-cell acute lymphoblastic leukaemia via determining the presence of a duplication of the MYB gene in cells taken from patients. The invention further relates to inhibitors capable of neutralizing the biological activity of MYB alone, or in combination with inhibitors capable of neutralizing the biological activity of NOTCH1, which can be used to treat T-cell acute lymphoblastic leukaemia.
Patent CA-2675383-A1 (CA)
Inventor: BENE BERNARD
IPC: G16H20/40
Filed: 2008-01-16
Abstract: The invention relates to a calculation and control system for determining whether a patient intended to follow several haemodialysis treatment sessions belongs to one group taken from several groups of hypertensive patients, the system comprising: a) means for determining the value of at least one parameter representative of the change in weight of the patient between dialyses for at least two sessions; b) means for determining the value of at least one parameter representative of the plasma conductivity of the patient for at least two sessions; c) means for determining the value of a parameter representative of the ion mass transfer of the treatment for at least two sessions; and d) programmed means for determining whether the patient belongs to a group of hypertensive patients depending on the change in weight of the patient between dialyses and/or on the plasma conductivity and/or on the ion mass transfer.
Patent CA-2678897-A1 (CA)
Inventor: RUBENS COURTNEY
IPC: C07D453/02
Filed: 2008-03-13
Abstract: The present invention relates to 11-(piperazin-l-yl)dibenzo[b,f][l,4]oxazapine compounds of the formula I (I) where the variables are as defined herein, their salts and pharmaceutically acceptable compositions thereof. Methods of preparing these compounds are also described. These compounds may be used in the treatment of disorders such as schizophrenia, treatment resistant schizophrenia, bipolar disorder, psychotic depression, treatment resistant depression, schizophrenia-associated depression, treatment resistant OCD, autism, senile psychosis, psychotic dementia, L-DOPA induced psychosis, psychogenic polydipsia, psychotic symptoms of neurological disorders, sleep disorders.
Patent CA-2680920-A1 (CA)
Inventor: LYNCH GARY
IPC: A61K31/54
Filed: 2008-03-13
Abstract: The present invention provides methods of increasing sexual arousal and performance behaviors in female mammals by administration of a therapeutically acceptable amount of a positive modulator of an AMPA-type glutamate receptor.
Patent CA-2685692-A1 (CA)
Title: A catalyst, its preparation and use
Inventor: KOWALESKI RUTH MARY
IPC: B01J23/78
Filed: 2008-05-01
Abstract: A dehydrogenation catalyst is described comprising an iron oxide, an alkali metal or compound thereof, and silver or a compound thereof. Further a process is described for preparing a dehydrogenation catalyst that comprises preparing a mixture of iron oxide, an alkali metal or compound thereof, and silver or a compound thereof and calcining the mixture. A process for dehydrogenating a dehydrogenatable hydrocarbon and a process for polymerizing the dehydrogenated hydrocarbon are also described.
Patent CA-2686330-A1 (CA)
Title: Reinforced oxide coatings
Inventor: LEE KANG N
IPC: C09D7/61
Filed: 2009-11-25
Abstract: A reinforced coating may include an oxide matrix and a reinforcement. In some embodiments, the reinforcement may include at least one of SiC and Si3N4. The reinforced coating may be deposited over a substrate, which may include a superalloy, ceramic or ceramic matrix composite (CMC). The reinforced coating may be deposited over the substrate alone or in combination with one or more additional oxide layers and/or a bond coat. The reinforced coating may be deposited using plasma spraying, physical vapor deposition, cathodic arc deposition, chemical vapor deposition, slurry dip coating, sol-gel coating, electrophoretic deposition, or another suitable deposition process.
Patent CA-2688904-A1 (CA)
Inventor: JARMON ROBERT M D
IPC: A61G7/057
Filed: 2009-12-18
Abstract: A body support for providing a beneficial effect has a frame and a first and a second plurality of flexible parallel bands, which are interdigitated. A  primary shaft rotatably mounted in a frame can tighten and slacken the first plurality of bands. This can be done by having the shaft wind and unwind the first plurality of bands or by appropriately positioning a camshaft or the like at one edge of the body support surface to adjustably hold each of the first plurality of bands there.  In the latter case the shaft provides a plurality of support locations at the first edge of the support surface that are moved, in order to alternately tighten and slacken the first plurality of bands. Other disclosed apparatus and methods can tighten and slacken the second plurality of bands as well.
Patent CA-2689289-A1 (CA)
Inventor: DANSEREAU DANIEL A
IPC: G05D7/00
Filed: 2008-05-01
Abstract: A method of method of calculating an ET value for an irrigation area is disclosed. The method includes a weather parameter measurement system collecting at least one weather parameter of a weather parameter area, the at least one weather parameter of the weather parameter area providing a representation of weather outside of the irrigation area. An irrigation area weather parameter is calculated providing a representation of the weather within the irrigation area from the at least one weather parameter of the weather parameter area. The ET value for the irrigation area is calculated from an N-dimensional continuous function using the at least one irrigation area weather parameter, wherein the N-dimensions includes at least a 3-dimensional spatial cube.
Patent CA-2689719-A1 (CA)
Inventor: FOUT GARY E
IPC: B01D33/00
Filed: 2010-01-05
Abstract: An apparatus and process for separating drilling fluid from drill cuttings are disclosed. The separations are performed in a drying auger unit, including: an inclined housing having side walls joined by a bottom and having an inlet end and an outlet end; at least one inlet for feeding a cuttings slurry to the inlet end; a helical auger located in the housing for transporting drill cuttings from the inlet end of the housing to the outlet end of the housing, and a drive for rotating the auger, an elevated pan disposed in and extending the length of the housing and having an arcuate cross section with a radius greater than a radius of the helical auger, wherein the pan is disposed proximate at least a lower quadrant of the helical auger; the housing further comprising a liquid recovery zone adjacent to the pan for transporting drilling fluids, separated from the drill cuttings during transport along the pan by the helical auger, to a liquid collection zone disposed adjacent to the inlet; an outlet for recovering drilling fluids from the liquid collection zone; and at least one fluid inlet nozzle for injecting a fluid into the liquid recovery zone to facilitate transport of any solids in the liquid recovery zone to the liquid collection zone; and at least one outlet for recovering drill cuttings having a reduced content of drilling fluids.
Patent CA-2690362-A1 (CA)
Inventor: LEGROS PAUL
IPC: B60G11/46
Filed: 2010-01-19
Abstract: An air ride suspension assembly or kit useful when converting a leaf spring suspension arrangement on a motor vehicle having a solid rear axle to one supported by the conversion suspension assembly is disclosed. The two sets of leaf springs which are attached to both sides of the vehicle chassis and the axle are removed and replaced by first and second upper support arms which are secured to the pre-existing leaf spring attachment sites on the chassis. The leading end of first and second lower trailing arms are each pivotally connected to a corresponding upper support arm proximate the front end of each support arm, and in the intermediate section of each trailing arm, are attached to the underlying axle by pivot connection means which permits the axle to pivot at right angles to the trailing arms. First and second inflatable air bladders are disposed between each support arm and trailing arm combination at a location rearward of the pivot connection means. The air ride conversion assembly can be supplied as a kit which may or may not include a known inflation control system for controlling air flow into and out of the air bladders which can also be obtained separately from third party sources. The conversion system has particular appeal to owners of light trucks who routinely carry heavy loads in the truck bed.
Patent CA-2691314-A1 (CA)
Inventor: BOSCH SAMUEL H
IPC: G06Q30/02
Filed: 2010-01-28
Abstract: A system of and method for rewarding an anonymous merchant-customer for performing multiple debit transactions on a defined set of merchant debit-machines comprises receiving data associated with a discrete one of the multiple debit transactions, generating and updating data associated with the anonymous customer without having the anonymous customer provide personally identifiable information, determining whether to reward the anonymous customer for performing one or more debit transactions, and if so, rewarding the anonymous customer. The method may be implemented on or by one or more merchant debit machines (e.g., automated teller machines (ATMs) and point-of-sale (POS) terminals), remote processors, financial institutions, general-purpose computers, or special-purpose computers.
Patent CA-2691492-A1 (CA)
IPC: F02D17/02
Filed: 2010-01-29
Abstract: A system for regulating the operation of an idling motor vehicle monitors one or more selected engine operational parameters such as coolant temperature, exhaust gas temperature, and catalytic converter temperature, and compares the measured parameters against selected benchmark criteria stored in the memory of a microprocessor.  The microprocessor controls the vehicle's ignition system to shut down the engine when the measured parameters come within the corresponding benchmark criteria. The system preferably but not necessarily operates in conjunction with a remote vehicle starter system. The system may also or alternatively be adapted to shut down an idling motor vehicle engine when total idling time reaches a specified maximum value, which may be selected based on idling time restriction bylaws. Accordingly, the system promotes reduced fuel consumption and mitigates environmental impacts by automatically regulating vehicle idling times, while also facilitating avoidance of idling time restriction bylaw violations.
Patent CA-2691787-A1 (CA)
Inventor: FUNAKI MAKOTO
IPC: A01N1/02
Filed: 2008-06-30
Abstract: This invention provides gels and matrices having a rigidity in the range of 150-750 Pa, methods of manufacturing same, and method of preserving a mesenchymal stem cell population or studying mesenchymal stem cells, comprising same.
Patent CA-2692581-A1 (CA)
Inventor: WU CHEE-MING JIMMY
IPC: H04W88/18
Filed: 2010-02-09
Abstract: In accordance with the teachings described herein, systems and methods are provided for downloading battery data to a mobile communication device. A system for downloading battery data to a mobile communication device may include a mobile communication device and a data server. The mobile communication device may be configured to monitor a battery operating condition and to receive a battery profile, the battery profile including battery data for use by the mobile communication device to calculate battery status information. The data server may be used for storing battery data, the data server being configured to receive the battery operating condition from the mobile communication device and, based on the battery operating condition, send the battery profile to the mobile communication device.
Patent CA-2693362-A1 (CA)
Inventor: TING SAN-LANG
IPC: B60J7/12
Filed: 2007-07-19
Abstract: A platform truck or trailer is equipped with a folding top including at least one piece of canvas supported on a collapsible framework. The collapsible framework includes two longitudinal tubes, a transverse tube extending between the longitudinal tubes, a motor connected to the transverse tube, and telescopic units. Each of the telescopic units includes an external tube connected to a related one of the longitudinal tubes, an internal tube inserted in the external tube, a threaded bolt located in the external and internal tubes and operatively connected to the motor, and a threaded sheath located in the internal tube and engaged with the threaded bolt.
Patent CA-2693967-A1 (CA)
Inventor: REDDY PANDURANGA ADULLA P
IPC: A61K31/497
Filed: 2008-07-17
Abstract: The present invention relates to novel heterocyclic amide compounds of Formula I: as disclosed herein or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are compositions comprising said compounds, and methods for using said compoundsfor treating or preventing a proliferative disease, an anti-proliferative disorder, inflammation, arthritis, a neurological or neurodegenerative disease, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease or a fungal disease.
Patent CA-2694899-A1 (CA)
Title: Mais presentant une digestibilite amelioree
Inventor: MURIGNEUX ALAIN
IPC: A23K50/15
Filed: 2008-07-29
Abstract: L'invention se rapporte à un maïs présentant une réduction de teneur de l'activité CAD2 due à la présence de l'allèle ?314, ainsi qu'à son utilisation pour l'ensilage.
Patent CA-2696914-A1 (CA)
Inventor: BURANACHOKPAISAN THITIWAN
IPC: A61K47/12
Filed: 2008-09-18
Abstract: Pharmaceutical compositions that include a poorly water-soluble therapeutic compound, an aqueous solvent, an chelator/antioxidant, a buffer or buffer component, and a bulking agent. The pharmaceutical compositions can be orally ingested or administered parenterally. The pharmaceutical compositions can further be lyophilized to form a pharmaceutically acceptable cake that can be administered orally, e.g., as a solid oral dosage form; or reconstituted and administered parenterally, e.g. as a single i.v.  bolus or iv infusion, or administered orally, e.g. as a drink solution.
Patent CA-2697241-A1 (CA)
Inventor: VRACHAN JEFFREY L
IPC: G02B27/22
Filed: 2007-08-22
Abstract: An apparatus (110) for producing aerial images having a combination of plastic spherical mirrors (45), beamsplitter polarizing filters (51), and light sources (115). An object (DO) to be displayed is illuminated, and its image is partially reflected by the beamsplitter (5 to a focusing mirror (45) and reflected to an aerial position (VI). A polarizer (CP) prevents ambient lights or images from degrading interfering with the aerial images.
Patent CA-2697596-A1 (CA)
Inventor: HU XIAO
IPC: G16H10/60
Filed: 2010-03-23
Abstract: Some embodiments provide a method and system for efficiently transferring medical images. Some embodiments receive a medical image in a first platform dependent format of a Picture Archiving and Communication System (PACS). The first platform dependent format is one that is accessible by a first format compliant device that includes a library that specifies how to decode the first format. Some embodiments transform the medical image from the first format to a second format. The second format includes decoded content of the first format that is viewable on a first format non-compliant device. The transformed image is then passed to the device for viewing. Additionally, some embodiments efficiently transfer medical images by identifying image settings for one or more devices and by passing requested images that are optimized by resizing the images according to the image settings of the requesting device.
Patent CA-2697765-A1 (CA)
Title: Method and apparatus for encoding metadata into a digital program stream
Inventor: BLANCHARD ROBERT
IPC: H04N21/236
Filed: 2008-08-28
Abstract: A method and apparatus for encoding data into a digital program stream includes receiving a digital program stream having a pre-allocated data channel, where the pre-allocated data channel has a pre-defined bandwidth. In one embodiment, metadata may be received and an unused portion of the pre-defined bandwidth of the pre-allocated channel may be determined. In another embodiment, metadata may be encoded into the unused portion of the pre- defined bandwidth.
Patent CA-2698149-A1 (CA)
Title: Method for preparing an injection device for injecting a mixture into an eye
Inventor: SANCHEZ JR ROBERT
IPC: A61F9/00
Filed: 2008-10-01
Abstract: Provided herein is a method for delivering a substance into the eye. The method includes providing a mixture and an interior surface of a dispensing chamber housing.  The mixture and dispensing chamber housing are near room temperature. The dispensing chamber housing and mixture are brought to a temperature range at which the mixture expands and is in a more liquid state. Air in a needle is maintained after the mixture expands and prior to an injection. The air in the needle and the mixture is injected into the eye. The air gap is calculated based on thermal expansion characteristics of the mixture.
Patent CA-2698485-A1 (CA)
Inventor: JUNG ULRICH
IPC: F04D27/02
Filed: 2008-09-16
Abstract: The invention relates to a vacuum pump (10) having a pump rotor (16), and active magnetic bearing (20,21), a safety bearing (22,23) associated with the magnetic bearing (20,21), an electric drive motor (18) having a motor stator having a plurality of stator coils (191,192,193) for driving the pump rotor (16), a brake relay (42) having a plurality of changers each having a base contact (62,63,64), a brake contact (44,45,46) and an operational contact (47,48,49), and a short circuit point (60) by way of which all brake contacts (44,45,46) of the brake relay (42) are directly connected to each other. All stator coils (191,192,193) are connected to the base contacts (62,63,64) of the changer, and can be connected directly to each other by way of the brake contacts (44,45,46) of the brake relay (42) and by way of the short circuit point (60), and can be connected to an inverter module (32) by way of the operational contacts (47,48,49).
Patent CA-2702431-A1 (CA)
Title: Ready-to-use bivalirudin compositions
Inventor: PALEPU NAGESH
IPC: A61P7/02
Filed: 2010-04-30
Abstract: Ready-to-use bivalirudin compositions, methods of using the ready-to-use bivalirudin compositions, and methods of preparing the ready-to-use bivalirudin compositions. The ready-to-use bivalirudin compositions comprise bivalirudin and one or more stabilizing agents. The one or more stabilizing agents may be buffering agents having a pKa of about 2.5 to about 6.5, pH-adjusting agents, polymers, preservatives, antioxidants, sugars or polyols, or a combination thereof. The ready-to-use bivalirudin compositions may also comprise [9-10]-cycloimido bivalirudin, [11-12]-cycloimido bivalirudin, or a combination thereof. The method of using the ready-to-use bivalirudin compositions comprises administering the ready-to-use compositions to a patient in need thereof. Further, the method of preparing the ready-to-use bivalirudin compositions comprises mixing bivalirudin with one or more stabilizing agents.
Patent CA-2702988-A1 (CA)
Inventor: WILSON JOHN ROBERT HOWE
IPC: C07F7/21
Filed: 2008-10-20
Abstract: [(03/2)Si CH2CH2SX] a[Si (04/2)] b[WSi (03/2)] c [VSi (03/2)] d wherein X is selected from (CR1R2 )eNR5 CO  NHR, (CR1R2)eNR5 CS NHR, W when present is selected from (CR6 R2)e ZR, (CH2)3 SRl (CH2)3 NRR1, (CH2)e SR8, CH2CH2S  (CR1R2 )fNR5 CO NHR, CH2CH2S (CR1R2 ),NR5 CS NHR, CH2CH2S (CH2)f OR; Z is 0 or S, R, R1-7 are independently selected from hydrogen, alkyl group, aryl group or alkylaryl group, R8 is selected from [CH2CH2NR1]p R2 and (CR1R2)m SR9 where R9 is hydrogen, Cl-22-alkyl group, and V is a group which is optionally substituted and selected from a C1-22-alkyl group, C2-22-alkenyl group, a C2-22-alkynyl group or an aryl group. The compounds are useful as immobilisation materials for bio-molecules including enzymes, cation and anion exchangers, organic and inorganic compound scavengers, solid phase purification or extraction materi-als, removal and purification of biological compounds including endotoxins, anti-microbial agents, hydrophilicity modifiers, flame proofing agents, antistatic agents, coatings for biomedical devices, water repellent films and coatings, solid phase synthesis materials and chromatography materials.