Patent EA-000177-B1 (EA)
Title: METHOD FOR DEPOSITING alpha-L-ASPARTYL-L-PHENYLALANINE-METHYL ESTER ON AN EDIBLE SUPPORT
Inventor: VLEGELS LEOPOLD FRANSISCUS VEI
IPC: A23L27/30
Filed: 1997-04-09
Abstract: 1. Method for depositing on an edible supporting material α-L-aspartyl-L-phenylalanine-methyl ester having a article size that is in the main smaller than 100 mkm, by mixing the α-L-aspartyl-L-phenylalanine-methyl ester and the upporting material in a dry form, characterised in that (1) the α-L-aspartyl-L-phenyl-alanine-methyl ester used (a) consists of particles formed in spontaneous agglomeration that are in the main smaller than 100 pm and/or of individual particles that are in the main smaller than 50 mkm, and (b) has a free bulk density of 350 kg/m<3> or lower, and c) is obtained through, successively, crystallisation of α-L-aspartyl-L-phenylalanine-methyl ester from an agueous edium with forced convection, granulation and subseguent mechanical reduction of the particles formed, resulting in a raction having the relevant properties, and that (2) that α-L-aspartyl-L-phenylalanine-methyl ester is for a short time rought into contact with particles of the edible supporting material having a particle size of 20 to 2000 mkm, in a weight ratio of at most 1:1, but not less than 1:30, relative to the supporting material, under mild mixing conditions. 2. Method according to Claim 1, characterized in that the α-L-aspartyl-L-phenylalanine-methyl ester has a particle size that is in the main smaller than 80 mkm. 3. Method according to Claim 1 or Claim 2, characterized in that the α-L-aspartyl-L-phenylalanine-methyl ester has a particle size that is in the main smaller than 50 mkm. 4. Method according to any one of Claims 1-3, characterized in that the a-L-aspartyl-L-phenylalanine-methyl ester has a particle size that is in the main smaller than 25mkm. 5. Method according to any one of Claims 1-4, characterized in that the supporting material is chosen from the groups comprising monosaccharides, disaccharides, oligosaccharides, polysaccharides, sugar alcohols, carbohydrates and polyols, food acids and their salts, protein hydrolysates and other dry nutrients, such as vanilla. 6. Method according to Claim 5, characterized in that the difference between the 10% largest particles and the 10% smallest particles of the supporting material does not exceed 500 mkm. 7. Method according to any one of Claims 1-6, characterized in that at least 80 wt.% of the supporting material falls within a particle size range whose upper and lower limits do not differ by more than 200 mkm. 8. Method according to any one of Claims 1-7, characterized in that α-L-aspartyl-L-phenylalanine-methyl ester and supporting material are mixed in a weight ratio in the range from 1:3 to 1:8. 9. Method for depositing on an edible support α-L-aspartyl-L-phenylalanine-methyl ester by mixing α-L-aspartyl-L-phenylalanine-methyl ester and supporting material in a dry form, characterized in that a composition obtained according to any one of Claims 1-8 is, in a subsequent process step, for a short time brought into contact with a further amount of supporting material, under mild mixing conditions, in a weight ratio of the composition originally obtained to the further supporting material in the range from 1:1 to 1:20. 10. Method according to any one of Claims 1-9, characterized in that the mixing in a dry form is done at a relative humidity of 70% or lower.