baber/WOPTO huggingface dataset:
Patent WO-2011046369-A2 (WO)
Inventor: KIM JAE WOO
IPC: G06Q50/00
Filed: 2010-10-13
Abstract: 본 발명은 문서화된 자료를 스캐닝하여 생성된 스캐닝된 이미지 자료를 고화질로 변환시키는 과정을 통하여 고해상도의 이미지 자료를 데이터베이스로 저장하는 것을 목적으로 한다. 또한 데이터베이스화된 이미지 자료와 이미지 자료의 주소값을 포함하는 바코드를 통해 사용자가 편리하게 이미지 자료에 접근할 수 있는 학습 시스템을 제공하는 것을 목적으로 한다. 본 발명에 따른 이미지 자료 데이터베이스화 시스템은 이미지 자료 및 상기 이미지 자료와 연관된 관련자료를 저장하는 데이터베이스; 상기 이미지 자료 및 상기 관련자료에 자료번호를 부여하는 자료번호 생성부; 상기 이미지 자료 및 상기 관련자료에 액세스할 수 있는 주소값을 저장하는 바코드를 생성하는 바코드 생성부; 및 상기 이미지 자료 및 바코드를 배열하여 문제지를 생성하는 문제 관리부;를 포함한다. 또한 본 발명에 따른 이미지 자료 데이터베이스화 시스템을 이용한 학습 시스템은 이미지 자료 및 상기 이미지 자료와 연관된 관련자료를 저장하는 데이터베이스; 상기 이미지 자료 및 상기 관련자료에 자료번호를 부여하는 자료번호 생성부; 상기 이미지 자료 및 상기 관련자료에 액세스할 수 있는 주소값을 저장하는 바코드를 생성하는 바코드 생성부; 및 상기 이미지 자료 및 바코드를 배열하여 문제지를 생성하는 문제 관리부;를 포함하는 이미지 자료 데이터베이스화 시스템; 상기 데이터베이스에서 액세스 되는 이미지 자료 및 상기 이미지 자료의 주소값을 저장하는 바코드를 포함하여 제공되는 문제지; 상기 바코드로부터 상기 주소값을 추출할 수 있는 바코드 스캐너; 상기 바코드 스캐너와 연결되어 상기 주소 정보를 수신하고 수신한 상기 주소 정보를 기초로 상기 데이터베이스에서 해당 주소의 정보를 수신하여 출력하는 정보 제공 단말기; 및 상기 정보 제공 단말기로 학생 식별정보 및 상기 이미지 문제의 풀이답안을 입력할 수 있는 입력장치를 포함한다.
Patent WO-2011142549-A2 (WO)
Inventor: KANG JEOM SUN
IPC: A47C27/00
Filed: 2011-05-02
Abstract: La présente invention se rapporte à un coussin fonctionnel à ressorts. Le coussin fonctionnel à ressorts selon la présente invention est fabriqué de telle façon que les caractéristiques des ressorts, y compris leur hauteur, leur dimension et leur module d'élasticité, sont ajustées en fonction des emplacements des ressorts. Ainsi, le coussin de la présente invention empêche que le bassin d'un utilisateur soit en contact direct avec le sol afin d'améliorer la ventilation et assurer le confort de l'utilisateur. Les ressorts du coussin de la présente invention distribuent de manière efficace le poids de l'utilisateur pour réduire efficacement les douleurs et supportent le bassin et les cuisses de l'utilisateur afin que celui-ci conserve une posture correcte. De plus, selon la présente invention, la surface supérieure du revêtement est constituée d'une maille aérée d'une extrême perméabilité à l'air, améliorant ainsi la perméabilité à l'air du coussin et assurant à l'utilisateur confort et douceur.
Patent WO-2011149295-A2 (WO)
Inventor: YOO HOUNG SIK
IPC: B32B7/02
Filed: 2011-05-26
Abstract: The present invention relates to a melt-processed moulded resin article comprising: a first resin layer; a second resin layer formed on the first resin layer; and an interface layer which comprises the first resin and the second resin and is formed between the first resin layer and the second resin layer, and this melt-processed moulded resin article can give outstanding mechanical properties and surface characteristics without the implementation of an additional coating process, and can exhibit the advantages of shortened processing time, increased productivity or reduced production costs.
Patent WO-2012005488-A2 (WO)
Inventor: PARK JAE GEUN
IPC: B23K37/00
Filed: 2011-07-05
Abstract: Disclosed are a welding monitoring system and method. The welding monitoring system according to an embodiment of the present invention comprises a welding machine; a current sensor which detects operating hours and welding current of the welding machine; a welding information database which stores the detected operating hours and welding current for each welding process of each welder, and stores preset information on charge consumption of the welding machine for each welding process; a data analysis unit which calculates charge consumption during the operating hours by using the detected operating hours and welding current of the welding machine, and compares the calculated charge consumption and the preset charge consumption for the process in which the welding machine has been operated to thereby determine whether the welder has achieved the purpose of the corresponding process; and a display unit which outputs a result of the determination of whether the welder has achieved the purpose of the corresponding process.
Patent WO-2012046955-A2 (WO)
Title: 질화물계 반도체 발광소자
Inventor: JEON SEONG RAN
IPC: H01L33/14
Filed: 2011-09-01
Abstract: 본 발명은 질화물계 반도체 발광소자에 관한 것으로, 전자와 정공의 파동함수의 공간적 분포를 일치 시키므로서 발광에 기여하는 전자와 정공의 재결합률을 증가시켜 발광효율을 향상시키기 위한 것이다. 본 발명에 따른 질화물계 반도체 발광소자는 n형 질화물층과, n형 질화물층 상에 형성된 활성층, 및 활성층 위에 형성된 p형 질화물층을 포함한다. 이때 스트레인 제어층은 활성층의 내부에 적어도 하나의 층으로 형성되며, 적어도 하나의 층 중 적어도 하나는 활성층의 양자우물층의 에너지 밴드갭보다 큰 에너지 밴드갭을 갖는다. 스트레인 제어층은 활성층의 양자우물층이 형성된 영역에 개재된다. 그리고 스트레인 제어층의 에너지 밴드갭은 활성층의 양자장벽층의 에너지 밴드갭보다는 작다.
Patent WO-2012081935-A2 (WO)
Title: Washing machine
Inventor: KIM YOUNG SUK
IPC: D06F39/08
Filed: 2011-12-16
Abstract: The present invention relates to a washing machine having a spouting module with a variable spouting direction. The washing machine of the present invention comprises: a cabinet which forms an outer appearance of the washing machine; a receiving module which is arranged in the cabinet and which includes a receiving case having a laundry receiving space; a spouting unit arranged in a horizontal direction in the receiving case to spout wash water; and a driving unit for moving the spouting unit in a reciprocating manner.
Patent WO-2012086974-A2 (WO)
Title: 태양전지 화학기상증착장치 기판 운송용 트레이의 가공방법
Inventor: PARK SANGBEEN
IPC: H01L21/673
Filed: 2011-12-19
Abstract: 본 발명은 태양전지용 PECVD 장치의 기판 고정을 위해, 트레이 상면에 홀(Hole)을 가공하고 상기 홀에 핀(Pin)을 결합하는 대신, 트레이 상면에 플라즈마 용사법으로 용사(spray)하여 엠보스(emboss) 형태의 핀(Pin)을 형성함으로 인해 트레이의 파손을 방지할 수 있는 태양전지 화학기상증착장치(PECVD) 기판 운송용 트레이의 가공방법에 관한 것이다.
Patent WO-2012091442-A2 (WO)
Title: 도로 경사면 변화에 따라 바퀴의 감속 또는 제동이 가능한 바퀴제어장치
Inventor: HONG SUNG BIN
IPC: B60B33/00
Filed: 2011-12-28
Abstract: 본 발명은 상술한 문제점을 해결하기 위해 안출된 것으로, 도로의 표면과 밀착되어 이동하는 바퀴의 회전력을 제어하기 위하여 인위적인 제어장치를 통하여 사용자가 일일이 조절하며 바퀴의 회전력을 제어하지 않아도 바퀴가 밀착되는 도로의 경사면 각도에 따라 편리하고 효율적으로 바퀴의 회전력을 자동 제어할 수 있는 도로 경사면 변화에 따라 바퀴의 감속 또는 제동이 가능한 바퀴제어장치를 제공한다. 상기와 같은 본 발명에 따르면, 사용자가 도로의 표면과 밀착되어 이동하는 바퀴의 회전력을 인위적인 제어장치를 사용하여 조절하지 않아도 회전하는 바퀴가 밀착되는 도로의 경사면 각도에 따라 편리하고 효율적으로 바퀴의 회전력을 자동 제어할 수 있다.
Patent WO-2012099406-A2 (WO)
Title: 생분해성 마이크로구조체가 결합된 약물 용출형 스텐트
Inventor: JUNG HYUNGIL
IPC: A61L27/54
Filed: 2012-01-19
Abstract: 본 발명은 스텐트가 병변부위로부터 이탈되는 것이 방지되며, 약물이 병변부위에 국소적으로 집중되어 전달될 수 있도록 구조가 개선된 약물 용출형 스텐트에 관한 것이다. 본 발명에 따른 약물 용출형 스텐트는 혈관에 삽입되어 혈관을 확장시키는 약물 용출형 스텐트에 있어서, 상기 스텐트에는 생체적합성 및 생분해성 고분자 물질로 이루어지며, 상기 스텐트의 확장시 혈관벽으로 삽입되는 돌기부가 형성되어 있다.
Patent WO-2012138067-A2 (WO)
Title: Procédé de transmission d'un message à un équipement utilisateur dans un système de communication sans fil et appareil associé
Inventor: LEE YOUNGDAE
IPC: H04W4/06
Filed: 2012-03-21
Abstract: L'invention porte sur un procédé de transmission d'un message par un équipement utilisateur (UE) dans un système de communication sans fil. Le procédé consiste à recevoir des informations de système comprenant un identificateur spécifique à partir d'un réseau, à recevoir un message de requête à partir du réseau, et à déterminer s'il faut ou non transmettre un message de réponse au réseau en réponse au message de requête sur la base de l'identificateur spécifique compris dans les informations de système.
Patent WO-2013009110-A2 (WO)
Title: Method of user equipment monitoring control information in a multiple node system and user equipment using the method
Inventor: KANG JI WON
IPC: H04L27/26
Filed: 2012-07-12
Abstract: There are provided a method of user equipment monitoring control information and user equipment using the method. The method includes receiving information about a first reference position for a first Enhanced-Physical Control Format Indication Channel (E-PCFICH) from a Base Station (BS); detecting the first E-PCFICH in a resource indicated by the information about the first reference position; obtaining information about a reference position for a second E-PCFICH based on the information about the first reference position, wherein each of the first E-PCFICH and the second E-PCFICH is a control channel including information about the size of the frequency domain for an Enhanced-Physical Downlink Control CHannel (E-PDCCH) for demodulating the control information by using a UE-specific Reference Signal (URS); and detecting the second E-PCFICH based on the obtained information about the reference position for the second E-PCFICH.
Patent WO-2017196138-A2 (WO)
Title: Système et procédé de recherche de chaîne de traitement de données précoces dans une conception de mémoire cache de grande dimension
Inventor: AVRUKIN ARKADI
IPC: G06F12/0802
Filed: 2017-05-12
Abstract: L'invention concerne un système et un procédé de recherche de chaîne de traitement de données précoces dans une conception de mémoire cache de grande dimension. Un mode de réalisation de l'invention comprend la recherche d'une ou plusieurs entrées d'étiquette d'un réseau d'étiquettes pour une partie d'étiquette de la demande d'accès à la mémoire et simultanément avec la recherche du réseau d'étiquettes, la recherche d'une file d'attente de travail de données d'un réseau de données en comparant une partie d'identificateur d'ensemble de la demande d'accès à la mémoire avec une ou plusieurs entrées de file d'attente de travail de données stockées dans la file d'attente de travail de données, à générer un indicateur de travail en attente indiquant si au moins une entrée de file d'attente de travail de données existe dans la file d'attente de travail de données qui correspond à la partie d'identificateur définie, et à envoyer la requête d'accès à la mémoire au réseau de données ou à stocker la requête d'accès à la mémoire dans un tampon latéral associé au réseau d'étiquettes sur la base de l'indicateur de travail en attente et d'un résultat de recherche de la recherche du réseau d'étiquettes.
Patent WO-2007148966-A2 (WO)
Title: Vessel provided with a foil below the waterline
Inventor: VAN OOSSANEN PIETER
IPC: B63B1/40
Filed: 2007-06-18
Abstract: Vessel (11) having a non-planing hull (12) provided with an attached foil (17) which is below the surface (8) of the water and spaced from the hull. The foil is attached in 5 proximity to the aft end of the vessel, and is oriented with a downward tilt of between greater than zero degrees and less than or equal to about 22-relative to the horizontal, to provide a lifting force with a force component in the forward direction. The foil can be located entirely behind the vessel, or partly below the aft hull portion of the vessel with no more than about half the foil being forward of the location (21) where the hull leaves the water. In the latter case, the hull is preferably provided with a recess (16).
Patent WO-2009131438-A2 (WO)
Title: Steam generation system having a main and auxiliary steam generator
Inventor: ROP PETER SIMON
Filed: 2009-04-20
Abstract: A steam generation system comprises a main steam generator and a back-up steam generator (20) which are both in fluid communication with a super heater (3) for superheating the generated steam. The superheater comprises a main heat source (6) for heating up a flow of heating gas. A back-up evaporator (2) is provided as a back-up steam generator for evaporating supplied water into steam. The back-up evaporator is connected in parallel to the main steam generator. An auxiliary heat source is provided for heating up the back-up evaporator. By controlling the auxiliary heat source (9), it is possible to supply more or less heat energy to the back-up evaporator to compensate for fluctuations in steam production of the main steam generator. The back-up evaporator is positioned away from the flow of heating gasses departing from the main heat source.
Patent WO-2009126035-A2 (WO)
Title: Device for holding beverage
Inventor: LANDMAN BERNARDUS CORNELIS JOHANNES
IPC: B65D1/04
Filed: 2009-04-08
Abstract: Holder (1) for beverage, comprising a container (2) manufactured substantially from plastic, provided with a neck (6), wherein in an inner space of the container liquid (3) is provided and on or in the neck a valve (23) is provided, through which valve extends a dispensing means, wherein the valve is fixed in or to the neck and wherein a pressure device (9) is provided for pressurizing the liquid in the container, wherein in or on the neck an element is suspended which at least partly extends in the inner space of the container and at least partly surrounds the dispensing means.
Patent WO-2011105935-A2 (WO)
Inventor: FEDOSEEV LEONID FEDOROVICH
IPC: F41H13/00
Filed: 2011-03-14
Abstract: The invention relates to the field of delivering armoured vehicles to combat zones using amphibious assault ships. The method for landing armoured vehicles consists in loading armoured vehicles onto an amphibious assault ship, delivering the vehicles via the ship to a coastal region of a combat zone, unloading the vehicles from the ship and delivering them to the scene of fighting. According to the invention, each armoured vehicle is provided with a flotation device. The flotation device renders tanks seaworthy and enhances the seaworthiness of amphibious armoured vehicles. As a result, the armoured vehicles are able to navigate safely under any sea conditions while remaining capable of travelling on land. The armoured vehicles are loaded from the water onto the amphibious assault ship and unloaded from the ship directly onto the water by the independent movement of the vehicles along the loading ramps of the amphibious assault ship. The armoured vehicles are delivered from the ship to the scene of fighting by means of the independent movement of the armoured vehicles, equipped with flotation devices, over the water so that they are capable of self-defence against air threats, surface vessels and submarines. The invention provides for: a significant reduction in the time required to unload all the armoured vehicles (with landing troops and cargo) as a result of the simultaneous independent exit thereof from the amphibious assault ship onto the water; the possibility of crossing independently to the scene of fighting with the assurance of safe navigation under any sea conditions; the reliable self-defence of the armoured vehicles against air threats, surface vessels and submarines; and an uninterrupted exit from the water onto the shore because the entire troop of armoured vehicles is able to traverse offshore shoals and shallows. As a result of the absence of landing craft, large numbers of armoured vehicles can be accommodated on a  Mistral  class ship.
Patent WO-2014021757-A2 (WO)
Title: Obtention et utilisation de mesures composites pour positionnement
Inventor: SIOMINA IANA
IPC: H04W64/00
Filed: 2013-03-25
Abstract: Selon l'invention, une mesure composite peut être utilisée pour déterminer une position d'un dispositif sans fil cible (1250). La mesure composite peut inclure un résultat d'au moins deux composantes de mesure. Les deux composantes de mesure peuvent être des mesures réalisées sur un signal physique et/ou des canaux transmis depuis un même nœud de transmission et mesurées par un nœud de mesure. Chaque composante de mesure inclut une ou plusieurs configurations de mesure, chaque configuration étant un type de configuration de ressource, de signal, d'émetteur et de récepteur. Les deux composantes de mesure ont des configurations d'au moins un type de configuration commun où les configurations du type commun sont différentes pour les deux composantes de mesure.
Patent WO-2016159876-A2 (WO)
Inventor: CHEN GUOXIN
Filed: 2016-03-28
Abstract: A sub assembly for coupling to a drill string, the assembly comprising; a mandrel; a sleeve arranged to be co-axially positioned about said mandrel; a first stop arranged to prevent axial movement of the sleeve along the mandrel in a first direction; a second stop arranged to prevent axial movement of the sleeve in a second direction; wherein said second stop is releasably engageable from the mandrel.
Patent WO-2023195916-A2 (WO)
Inventor: WANG XINYAO
Filed: 2023-03-23
Abstract: The disclosure discloses a video processing method and apparatus, an electronic device and a medium. The video processing method comprises: on the basis of video information of an original video, determining a candidate slice information set of the original video; on the basis of each piece of candidate slice information in the candidate slice information set, segmenting the original video into a plurality of video clips; inputting the plurality of video clips into an evaluation model, and determining probability information of each piece of candidate slice information; and on the basis of the probability information corresponding to each piece of candidate slice information, determining target slice information of the original video.
Patent WO-2010016811-A2 (WO)
Title: Structure modulaire sur un sol surélevé
Inventor: NALCA AKIN
IPC: E04F15/024
Filed: 2009-08-04
Abstract: L'invention concerne des structures modulaires montées devant être fixées sur la surface horizontale ou verticale d'un espace et pouvant être démontées, selon les besoins, afin d'être remontées. La structure modulaire décrite dans l'invention est constituée d'un ou de plusieurs éléments panneaux et les éléments de fixation utilisés pour l'assemblage de ces composants peuvent être repositionnés de manière répétée. La structure modulaire décrite dans cette invention qui est conçue pour être utilisée en tant que sol ou que paroi d'affichage pour l'extérieur ou pour l'intérieur (par exemple, dans des espaces d'exposition, tels que des foires-expositions, des galeries d'art, dans des conceptions intérieures de bureaux et de salles d'exposition), est composée de panneaux de sol de grandes dimensions, des orifices peuvent être ménagés sur ces panneaux et permettent d'utiliser les panneaux avec d'autres unités d'expositions, et des éléments de socle qui surélèvent les éléments de raccord, le panneau de sol et le cadre formant la sous-structure.
Patent TR-2021005532-A2 (TR)
Title: Hava süspansi̇yon körük kaliplari i̇çi̇n marka parçasi ve marka parçalarini söküp takma mekani̇zmasi
Inventor: OĞUZHAN ERFEN
IPC: B25H7/00
Filed: 2021-03-26
Abstract: Buluş özellikle ağır vasıta sınıfındaki araçlarda kullanılan hava süspansiyon körüğünün üretimi için kullanılan kalıpların içine takılıp, sökülebilen ve termoplastik, termoset, kompozit malzeme, teflon, yarı metal, metalden yapılmış marka parçasının,  marka parçası yuvasında bulunan, değiştirme mekanizmasına bağlı vidanın bir alyan tarafından çevrilmesi ile marka parçası yuvasındaki değiştirme mekanizması tırnağına dayanarak yukarı doğru hareket ederek, vidanın dişin sonuna dayanması ile marka gövdesinden kolay bir şekilde ve deformasyona sebep olmadan ayrılmasının sağlanması ile ilgilidir.
Patent TR-2021016490-A2 (TR)
Title: Morfi̇n ve morfi̇n ekstraktlarinda reti̇kuli̇n i̇mpüri̇tesi̇ni̇n saflik ve stabi̇li̇te spesi̇fi̇kasyonu olarak kullanilmasi
Inventor: OZAN FİDAN
IPC: A61K31/485
Filed: 2021-10-22
Abstract: Morfin, morfin tuzları, hidrat ve solvatları ile morfin ekstraktlarında, yarı mamullerinde ve ara ürünlerinde saflık, stabilite veya raf ömrü tayini için HPLC yöntemi ile retikulin miktarının belirlenmesi esasına dayanır.
Patent TR-2021017825-A2 (TR)
Title: Kontrollü boşaltim sağlayan bunker kapaği
Inventor: İRFAN AHMET KURAN
IPC: B02C23/00
Filed: 2021-11-16
Abstract: Bu buluş, bunker içerisindeki atıkların shredder öğütücü üzerine istenilen miktarda kontrollü olarak çekilmesini/dökülmesini sağlayan bunker kapağı ile ilgilidir.
Patent TR-2022013116-A2 (TR)
Title: Sosyal sorumluluk çalişmalari taki̇p ve katilim si̇stemi̇
Inventor: SELAMİ ÇİFTÇİ
IPC: G06Q30/00
Filed: 2022-08-19
Abstract: Buluş, şirketlerin, çalışanlarının ilgi ve becerileriyle örtüşecek, onların vakitlerine uyacak etkinlikleri bulmasını, kişilerin bu etkinliklere katılmasını, etkinlik sonrası kazanımlarını ve geri bildiriminin takip edilmesini sağlayan bir sistem ile ilgilidir.
Patent WO-2004063293-A2 (WO)
Title: Encre effaçable pour instrument d'ecriture
Inventor: ROSENBAUM BARRY
IPC: C09D11/16
Filed: 2004-01-09
Abstract: Dans au moins un mode de réalisation, la présente invention se rapporte à une composition d'encre effaçable, qui peut être particulièrement avantageusement utilisée dans un instrument d'écriture pour simuler l'aspect d'un crayon à mine de graphite. La composition selon l'invention comprend un système de solvant, un élastomère et un pigment. Le système de solvant utilisé dans le cadre de la présente invention contient un ester organique et un composant sélectionné parmi un cycloalcane éventuellement substitué, un cycloalcanone éventuellement substitué, un cycloalcène éventuellement substitué, ou des mélanges de ces derniers. Le système de solvant est présent en une quantité suffisante pour permettre à la composition d'encre effaçable de s'écouler dans un instrument d'écriture. La composition d'encre effaçable selon l'invention contient de préférence un pigment renfermant du graphite et du noir de carbone. Enfin, la composition d'encre effaçable contient éventuellement un plastifiant, un butène liquide, ou un ou plusieurs additifs sélectionnés parmi un inhibiteur de corrosion, un composé fluidifiant, et des mélanges de ces derniers.
Patent WO-2004077376-A2 (WO)
Title: Lane tracking system employing redundant image sensing devices
Inventor: CRAWSHAW RICHARD D
IPC: B60Q1/52
Filed: 2004-02-20
Abstract: A lane tracking system for a vehicle (10) employing redundant imaging devices (12, 14) with different fields of view (16, 20) is disclosed. The imaging devices (12, 5 14) are oriented in generally opposite directions so glare or other harsh lighting hampering one imaging device will not affect the other device. The appropriate image is selected based on image quality and used to detect lane markers (24) and vehicle position. A preferred application for lane departure warning is also disclosed.
Patent WO-2004079881-A2 (WO)
Title: Generateur de force motrice mettant en application un aimant ou un electro-aimant et machine electrique rotative ou motrice integrant ce generateur
Inventor: KINOSHITA YUKIO
IPC: B60K1/00
Filed: 2004-03-04
Abstract: L'invention concerne des moyens servant à générer une force motrice par réduction ou élimination du recours à toute force motrice extérieure et consistant à utiliser des aimants ou des électro-aimants. Ces moyens consistent en particulier à mettre en application seuls ou combinés les points suivants : (1) affectation de la même polarité à un pôle du stator et à un pôle du rotor opposés dans une machine motrice ; (2) affectation de la même polarité (N ou S) à soit la totalité des pôles magnétiques du stator, soit à la totalité de ceux du rotor afin de déclencher une force de répulsion ou d'attraction au moment d'un déplacement relatif ou d'une rotation de ces pôles magnétiques ; régulation simultanée (3) de la génération d'une force motrice dans un sens défini en fonction de la structure ou de la configuration du stator ou du rotor.
Patent WO-2004085345-A2 (WO)
Title: Esters d'acide carboxylique et d'estradiol substitues en 15$g(a) en tant qu'oestrogenes localement actifs
Inventor: HOCHBERG RICHARD
IPC: A61K31/56
Filed: 2004-03-09
Abstract: L'invention concerne des analogues de l'estradiol, qui, dans le mode de réalisation préféré, agissent comme oestrogènes localement actifs sans action systémique signifiante. La présente invention porte également sur une série de composés d'ester d'estradiol 15 alpha, lesquels développent une excellente activité biologique pour être utilisés dans des compositions pharmaceutiques destinées au traitement de symptômes associés à la ménopause. La présente invention concerne donc des composés de formule (I), dans laquelle X est (CH2)m, R désignant H, un groupe alkyle C1 à C5, éventuellement substitué par au moins un groupe halogène tel que CH2CH2F ou un autre groupe (par ex., un groupe CH2CHF2, CH2CF3 ou CF3), et m étant un nombre de 0 à 5, et de préférence de 0 à 2.