baber/WOPTO huggingface dataset:
Patent EP-2029731-A4 (EP)
Title: Regulation of protein activity by reversible acetylation
Inventor: SCHWER BJOERN
IPC: G01N33/50
Filed: 2007-06-12
Abstract: This invention discloses the first cellular acetylated substrate protein of SIRT3, Acetyl-CoA synthetase 2 (AceCS2), which is a mitochondrial matrix protein. AceCS2 is reversibly acetylated at lysine 642 (Lys642) in the active site of the enzyme. The mitochondrial sirtuin SIRT3 interacts with AceCS2 and deacetylates Lys642 both in vitro and in vivo. Deacetylation of AceCS2 by SIRT3 activates the acetyl-CoA synthetase activity of AceCS2. Thus, a mammalian sirtuin directly controls the activity of a metabolic enzyme via reversible lysine acetylation. Modulators of the acetylation status or the activity of AceCS2 are useful for the treatment of pathological conditions, such as type II diabetes, hypercholesterolemia, hyperlipidemia, and obesity.
Patent EP-2123434-A4 (EP)
Title: Manufacturing method for pneumatic tire
Inventor: HASHIMURA YOSHIAKI
IPC: B29D30/30
Filed: 2008-02-19
Abstract: Provided is a manufacturing method for a pneumatic tire including the steps of: shaping a cylindrical film formed of a thermoplastic resin or a thermoplastic elastomer composite in which a thermoplastic resin is blended with an elastomer, folding the film into a sheet shape, laminating rubber layers on both surfaces of the folded film, opening the laminate of the film and the rubber layers into a cylindrical shape, fitting the laminate thus opened on a tire making drum, forming the tire pneumatic tire including the film as an air permeation preventing layer, and curing the uncured tire. In the method, when the rubber layers are laminated on the both surfaces of the folded film, positions of the rubber layers in a width direction are displaced from each other such that an end portion of one of the rubber layers is arranged to protrude from an end portion of the film and an end portion of the other one of the rubber layer is arranged on an inner side, in the width direction, of the protruding end portion of the one of the rubber layers, and the protruding end portion of the one of the rubber layers is caused to cover the end portion of the other one of the rubber layers in a state where the laminate is fitted on the tire making drum. By employing the manufacturing method for the pneumatic tire, troubles due to a splice portion of the rubber layers can be reduced.
Patent EP-2207981-A4 (EP)
Title: Connecting device for connection between a brake disc and a hub and method for mounting
Inventor: ILG TORVALD
IPC: F16D65/12
Filed: 2008-10-01
Abstract: The invention relates to a connecting device for connection between a brake disc and a hub. The brake disc is fitted on the hub via splined connection with recesses on the brake disc and protrusions on the hub. The connecting device is made of non-rusting material and intended to be fitted between a side surface of a recess and an adjacent side surface of a protrusion. According to the invention, the connecting device has two mutually abutting layers. These are connected to one another and separable from one another by only an axial relative movement between the layers. The invention also relates to a method for fitting a brake disc on a hub.
Patent EP-0042380-A4 (EP)
Title: Method for achieving ideal impurity base profile in a transistor.
Inventor: CROWDER BILLY LEE
IPC: H01L21/331
Filed: 1979-12-28
Abstract: A method for making a transistor having base, collector, and emitter regions, where the impurity doping profile of the intrinsic (32) and extrinsic (22) base regions can closely approximate that which is ideal for the transistor. The extrinsic (22) and intrinsic (32) base regions are formed in separate steps, where the extrinsic base region (22) is formed first, followed by formation of the intrinsic base region (32). The portion of the extrinsic base region located over the area where the intrinsic base region is to be formed is removed, leaving an opening (26) through which both the emitter (30) and the intrinsic base regions (32) are formed. Thus, the effect of the step in which the extrinsic base region is formed is removed prior to formation of the intrinsic base region. Furthermore, the extrinsic base region is protected during formation of the intrinsic base region. This technique can be applied to processes using either ion implantation or diffusion to form the emitter and base regions of the transistor.
Patent EP-0128956-A4 (EP)
Title: Low firing ceramic dielectric for temperature compensating capacitors.
Inventor: HODGKINS CHARLES EDWIN
IPC: H01B3/12
Filed: 1983-12-22
Abstract: A low fired, temperature compensating dielectric composition. The invention dielectric is formed of a base ceramic and a frit material. The base ceramic includes magnesium oxide, titanium oxide, calcium oxide, alumina, silica and at least one oxide of a rare element from the group of niobium, neodymium, tantalum, lanthanum, yttrium and praseodymium. The preferred oxides are those of niobium alone or with neodymium
Patent EP-0231174-A4 (EP)
Title: Contact lens.
Inventor: VOLK DAVID
IPC: G02C7/04
Filed: 1985-08-08
Abstract: A contact lens wherein at least one of its surfaces, generally the posterior surface, is an aspheric surface of revolution which decreases in curvature from its apex to its periphery and which varies in a continuous and regular manner in eccentricity from its apex to its periphery. The novel surface is defined in terms of three parameters: apical radius of curvature; apical eccentricity; and collectively one or more derivatives of eccentricity. The lens with the novel surface posterior is so designed that the novel surface approximates the contour of the cornea while at the same time producing optical properties in the lens for optimal correction of the refractive error of the non-presbyopic eye, and when presbyopia exists, for the correction of the refractive error of the eye and presbyopia.
Patent EP-0214245-A4 (EP)
Title: Altering pore size distributions.
Inventor: FORD DOUGLAS LYONS
IPC: B01D69/02
Filed: 1986-03-06
Abstract: PCT No. PCT/AU86/00053 Sec. 371 Date Oct. 28, 1986 Sec. 102(e) Date Oct. 28, 1986 PCT Filed Mar. 6, 1986 PCT Pub. No. WO86/05117 PCT Pub. Date Sep. 12, 1986.Pores that are smaller than or larger than a predetermined range of pore sizes in a porous membrane barrier are blocked with a controlled porosity blocking agent. The pores are first filled with a liquid so as to remove any air therein and then subjected to a transmembrane gas blow at a pressure which will clear the larger pores of the liquid. The larger gas filled pores or the smaller liquid filled pores are then blocked by a blocking agent using a polymer-forming chemical reaction, a precipitate-forming chemical reaction or the physical deposition of solids.
Patent EP-0270615-A4 (EP)
Title: TRANSFORMATION AND FOREIGN GENE EXPRESSION IN -i(BRASSICA) SPECIES.
Inventor: MOLONEY MAURICE M
IPC: A01H1/04
Filed: 1987-05-26
Abstract: Brassica species are produced by transformation of cell culture with foreign DNA followed by regeneration of plants from transformed cells. The cells and the plants produced thereby are capable of expressing the foreign gene. The Brassica species are transformed employing a manipulated Agrobacterium transformation system, followed by regeneration of the plant tissue into plants.
Patent EP-0323979-A4 (EP)
Title: Rotary machine
IPC: F01C20/00
Filed: 1987-09-29
Abstract: A rotary machine which may operate as an internal combustion engine, fluid motor, fluid pump or compressor. The rotary machine comprises a machine housing (11) having a cavity (13). A rotor (23) is rotatably supported in the cavity. A plurality of sliding vanes (31) are arranged to form with the housing (11) and the rotor (23) a plurality of chambers (35) which vary in volume on relative rotation between the rotor and the housing. The rotor (23) can be shifted relative to the housing (11) in a direction transverse to the axis of rotation of the rotor in order to vary the volumetric capacity of each chamber (35) at any rotational position. The means for selectively shifting the rotor (23) relative to the machine housing (11) comprises bearings rotatably supporting the rotor and mounted in respective bearing housings. The bearing housings are selectively rotatable about an axis eccentric to the rotational axis of the rotor whereby rotation of the bearing housings effects said shifting movement of the rotor relative to the machine housing. Also disclosed is an arrangement of seals on the rottor which serve to maintain sealing of the chambers whilst accommodating shifting movement of the rotor.
Patent EP-0370106-A4 (EP)
Title: Treading device for wheels
IPC: B60C27/00
Filed: 1988-05-23
Abstract: According to the present invention, rotors (3) and a retainer (4) are moved on a road surface in accordance with the rotation of a wheel (7), and, as long as there is a relative movement between the wheel (7) and road surface (5), a belt-like member is turned. While the vehicle travels normally, the wheel rotates on a blade placed stationarily on the road surface; and, even when the slipping of the wheel occurs, the wheel bumps off the blade backward as it slips, so that the belt-like member is thereby further turned. When the wheel and blade slip on the road surface when the wheel is braked, the road surface turns the belt-like member. Accordingly, the blades are moved down sequentially in any case to be arranged on the road surface in good order and rest, and the wheel runs on the blades as it treads thereon. Therefore, the treading of the blade is done reliably. Even when the size of the blades is small, an unreasonably large force is not applied thereto, and this enables the dimensions of a blade retaining means to be reduced.
Patent EP-0378641-A4 (EP)
Title: Novel antimicrobial peptide, compositions containing same and uses thereof
IPC: C07K1/14
Filed: 1989-05-26
Abstract: This invention provides a purified polypeptide useful as an antimicrobial agent. This purified polypeptide has been derived from human granulocytes, and has a molecular weight of about 3,700 daltons and the N-terminal amino acid sequence val-cys-ser-cys-arg-leu-val-phe-cys-arg-arg-thr-glu- leu-arg-val-gly-asn-cys-leu-ile-gly-gly-val-ser-phe-thr-try-cys-thr-ar g-val. This invention also provides methods for producing this polypeptide, pharmaceutical compositions containing the polypeptide, and uses thereof.
Patent EP-0460097-A4 (EP)
Title: Method and diagnostic test kit for detection of anti-cardiolipin
Inventor: STERHAN MARCIA
IPC: G01N33/543
Filed: 1990-02-26
Abstract: A method and apparatus optimized as a diagnostic sandwich assay test kit, which has immobilized cardiolipins onto a precoated support surface utilized for the purpose of detection of antibodies specific to such compounds by either ELISA (Enzyme Linked Immunosorbent Assay) or FIA (Fluorescent Immunoassay) techniques.
Patent EP-0513213-A4 (EP)
IPC: A61H31/02
Filed: 1991-01-30
Abstract: Appareil de compression toracique oscillatoire (10) destiné à aider au détachement et à l'élimination de mucus des poumons d'un patient (12) atteint de fibrose kystique. L'appareil comprend un mécanisme (18) destiné à appliquer de l'air sous pression à une vessie (16) recouvrant le torax d'une personne, ainsi qu'un mécanisme (116) destiné à évacuer l'air sous pression de la vessie. De plus, l'appareil comprend un mécanisme (22) destiné à alimenter la vessie en air, en une configuration d'impulsions présentant des temps de montée élevés analogue à des ondes rectangulaires. Le patient peut commander (162) l'application des impulsions sous pression ainsi que la vitesse de ces dernières.
Patent EP-0485628-A4 (EP)
IPC: B26D7/32
Filed: 1991-05-30
Abstract: Le dispositif décrit sert à fabriquer des feuilles selon un procédé simple et avec une grande productivité, feuilles qui sont utilisées pour produire en grandes séries des palettes en matériau en feuilles à base de résine synthétique. Ce dispositif utilise trois étapes: une première étape (1001) où s'effectue l'acheminement du matériau en feuilles, lequel a une forme spécifiée et des coins, une deuxième étape (1002) où sont coupés lesdits coins au moins et où les feuilles sont façonnées à la forme désirée; ainsi qu'une troisième étape (280) où sont stockées les feuilles ainsi obtenues.
Patent EP-0618834-A4 (EP)
Inventor: MILLER JOHN D
IPC: B01D29/62
Filed: 1992-12-22
Abstract: Un système de filtrage dynamique comprend un ensemble à filtres dynamiques comprenant un ou plusieurs éléments filtrants (148) ainsi qu'un ou plusieurs organes (151) disposés à l'intérieur d'un logement (105). Les éléments filtrants ainsi que les organes sont intercalés et agencés pour tourner les uns par rapport aux autres.
Patent EP-0598136-A4 (EP)
Title: Construction of sealing through-hole penetrating through metallic partitioning member.
Inventor: TAMURA MORIO-KANDATSU-MACHI
IPC: G01L19/00
Filed: 1993-06-03
Abstract: In a construction wherein a hole (5) is formed in a base member (4) made of metal as being a partition member for gas-tightly or liquid-tightly partitioning regions disposed on opposite sides, and an electric conductor (1), a pipe member, through which gas or liquid is caused to flow, a heat pipe, through which a heat transfer medium is caused to flow, an optical fiber for transmitting optical signals, and the like are passed through the hole (5) to be led out therefrom, each of said members is disposed through a sealing member (3) made of synthetic resin, said hole (5) is sealed by sealing by plasticity deformation action of the base member (4) and the deformation action through the utilization of elastic plasticity of the sealing member (3), whereby high pressure-tight performance is achieved against superhigh pressure, so that said hole (5) can be sealed stably for a long period of time.
Patent EP-0666715-A4 (EP)
Inventor: HARRIS DONALD W
IPC: A23L9/20
Filed: 1993-10-28
Abstract: L'invention se rapporte à un procédé de préparation d'aliments à teneur réduite en matière grasse, qui consiste à utiliser une amylopectine rétrogradée, hydrolisée, fragmentée et soumise à un traitement thermique. L'amylose est précipitée et hydrolysée à l'aide d'un acide ou de l'α-amylase, les matières solubles sont enlevées par un traitement thermique et les solides obtenus sont fragmentés pour former une dispersion aqueuse pouvant être utilisée pour remplacer la matière grasse dans une variété de formulations alimentaires. L'amylose peut être dérivée d'un amidon naturel qui contient de l'amylose, par exemple l'amidon de maïs commun et un amidon de maïs à haute teneur en amylose, par gélatinisation de l'amidon, suivie de la précipitation de l'amylose.
Patent EP-0690680-A4 (EP)
Title: Peanut blanching process
Inventor: FORREST JAMES T
IPC: A23N5/00
Filed: 1994-02-24
Abstract: An improved apparatus for blanching nuts, particularly peanuts, is provided wherein nuts are fed onto a conveyor belt (20) by a single feeder means (56) which carries them against a diagonally positioned nut engaging means (50) that has a nut discharge end which extends beyond the edge of the conveyor belt (20). The nuts are rotated by the simultaneous forces of the conveyor belt (20) and the nut engaging means (50), during which their skins are removed. After the nuts traverse the width of the conveyor belt (20) against the nut engaging means (50), they are deposited into a collecting hopper at the side of the conveyor belt, where they await the next stage of preparation.
Patent EP-0708653-A4 (EP)
Title: Assay and reagents for identifying anti-proliferative agents
Inventor: DRAETTA GIULIO
IPC: A61P43/00
Filed: 1994-06-06
Abstract: The present invention makes available assays and reagents for identifying anti-proliferative agents, such as mitotic and meiotic inhibitors, especially inhibitors of cdc25 phosphatase. The present assay provides a simple and rapid screening test which relies on scoring for positive cellular proliferation as indicative of anti-mitotic or anti-meiotic activity, and comprises contacting a candidate agent with a cell which has an impaired cell-cycle checkpoint and measuring the level of proliferation in the presence and absence of the agent. The checkpoint impairment is such that it either causes premature progression of the cell through at least a portion of a cell-cycle or inhibition of normal progression of the cell through at least a portion of a cell-cycle, but can be off-set by the action of an agent which inhibits at least one regulatory protein of the cell-cycle in a manner which counter-balances the effect of the impairment.
Patent EP-0731775-A4 (EP)
Title: High temperature evaporation inhibitor liquid
Inventor: ZEHEB RON
IPC: C02F1/00
Filed: 1994-11-02
Abstract: The present invention provides a liquid evaporation inhibitor which is suitable for use in high temperature applications; e.g., above 70 °C. The evaporation inhibitor liquid comprises a mixture of an alkane, a non-volatile oil, preferably a vegetable oil and a surfactant. The alkane is present in the mixture in an amount sufficient to provide a density which promotes floating on an aqueous medium and to cover an aqueous medium. The non-volatile oil is present in the mixture in an amount sufficient to inhibit evaporation of the mixture at temperatures above 70 °C. The surfactant is present in the mixture in an amount sufficient to maximize the contact surface area between the evaporation inhibitor liquid and the aqueous medium.
Patent EP-0688798-A4 (EP)
IPC: C08F222/40
Filed: 1995-01-10
Abstract: L'invention concerne un copolymère maléïmidique comprenant des motifs monomères maléïmidiques, des motifs monomères vinyliques aromatiques et d'autres motifs monomères vinyliques, ainsi qu'une composition de résine maléïmidique comprenant ledit copolymère et un polymère greffé du type caoutchouc. Le copolymère maléïmidique selon l'invention possède les caractéristiques suivantes: I) sa teneur en monomère maléïmidique résiduel est au maximum de 0,1 % en poids, et sa teneur en composants volatils autres que le monomère maléïmidique est au maximum de 0,5 % en poids; II) sa teneur en un composé obtenu à partir d'au moins un monomère sélectionné dans le groupe comprenant un monomère maléïmidique, des monomères vinyliques aromatiques et d'autres monomères vinyliques, et ayant une masse moléculaire moyenne en poids de 200 à 1000, déterminée par chromatographie sur gel, est de 2-10 % en poids; III) son indice de jaunissement est au maximum de 30; et IV) sa viscosité intrinsèque est de 0,3 à 1,5.
Patent EP-0776523-A4 (EP)
Inventor: STAUFFER JOHN E
IPC: H05H1/22
Filed: 1995-06-29
Abstract: Des boulettes de combustible utilisées comme cibles dans un appareil employant la fusion thermonucléaire par confinement inertiel (fusion au laser) sont fabriquées à partir d'hydrocarbures polymèeres lourds dans lesquels l'hydrogène lié a été remplacé par du tritium. Le polymère requis est préparé par polymérisation d'un ou de plusieurs monomères contenant du carbone et du tritium. Les boulettes creuses sont remplies avec du combustible thermonucléaire, par exemple, un mélange de deutérium-tritium. Afin d'améliorer la sphéricité des boulettes et l'uniformité de l'épaisseur de leur paroi, il est prévu de les fabriquer dans un espace à gravité presque nulle.
Patent EP-0744435-A4 (EP)
Inventor: ISHIZAKI KUNIHIKO
IPC: C07D233/64
Filed: 1995-12-08
Abstract: On produit une résine absorbant l'eau en dispersant un agent de gonflement solide, présentant un diamètre de particule moyen compris entre 1 et 100 νm, dans une solution aqueuse contenant un monomère insaturé et un agent de réticulation, et en polymérisant le monomère. La résine obtenue présente une excellente aptitude à la diffusion de liquides aqueux et d'excellentes caractéristiques d'absorption de l'eau telles que la vitesse d'absorption de l'eau, la capacité de rétention de l'eau et la sécheresse au toucher, tout en ayant une teneur réduite en composants hydrosolubles et en monomères résiduels. Des matériaux sanitaires préparés à partir d'une telle composition de résine présentent une vitesse d'absorption de l'eau et une capacité d'absorption de l'eau augmentées et permettent d'éviter les fuites.
Patent EP-0774340-A4 (EP)
Inventor: KAIDO HIROYUKI
IPC: B60C5/14
Filed: 1996-04-15
Abstract: La présente invention concerne un procédé de production de pneumatiques utilisant des couches simples ou multiples de film thermoplastique analogue à un ruban ou tubulaire, pour obtenir une couche empêchant l'air de traverser. Ce procédé comprend l'application d'une composition adhésive visqueuse à au moins une partie, soit d'un joint situé entre les films thermoplastiques, soit d'une section comprise entre le film thermoplastique et une partie du penumatique lui faisant face. Cette composition adhésive visqueuse a un constituant polymère dont les valeurs absolues de différence de tension superficielle critique entre un constituant en caoutchouc du pneumatique et un constituant polymère d'une couche superficielle du film thermoplastique sont de 6mN/m ou moins, respectivement.
Patent EP-0838068-A4 (EP)
Inventor: KUMAR RAKESH
IPC: G06T15/10
Filed: 1996-07-08
Abstract: L'invention concerne un système (10) de traitement d'images pour transformer une scène (15) en une mosaïque, choisir un nouveau point de vue pour la scène et restituer à partir de cette mosaïque une image de synthèse représentant la scène depuis ce nouveau point de vue (112). L'image de synthèse est ensuite combinée avec une seconde image (114). La combinaison de la seconde image et de l'image de synthèse produit une image composite constituée par une combinaison réaliste d'objets de la seconde image et de la nouvelle scène. En utilisant ce système, un arrière-plan ou d'autres scènes n'ont besoin d'être créés qu'une fois, puis restitués comme image par le système. Ensuite, par des procédés de traitement d'images, une vue quelconque de la scène peut être synthétisée et combinée avec des acteurs ou des objets saisis séparément, pour produire l'image composite. Dans ces conditions, un arrière-plan ou une autre scène peut être réutilisé de manière répétée, sans créer à nouveau la scène réelle.
Patent EP-0868174-A4 (EP)
IPC: A61P35/00
Filed: 1996-08-21
Abstract: Disclosed are anticancer tumor soft gelatin capsules comprising a 1,2,4-benzotriazine oxide and an oily excipient selected from the group consisting of soybean oil and fractionated coconut oil.
Patent EP-0943326-A4 (EP)
Title: Powdery composition for nasal administration
Inventor: DOHI MASAHIKO
IPC: A61K9/00
Filed: 1997-02-26
Abstract: The present invention relates to a powdery composition for nasal administration, which is characterized in that   (1) the composition contains (i) a drug, (ii) a water-absorbing and gel-forming base material such as hydroxypropyl cellulose or hydroxypropylmethyl cellulose and (iii) a water-absorbing and water-insoluble base material such as crystalline cellulose or  alpha -cellulose, (2) wherein the amount of the water-absorbing and gel-forming base material is about 5-40 wt % based on the total of the water-absorbing and gel-forming base material and the water-absorbing and water-insoluble base material, and (3) wherein the drug is unevenly dispersed more on/in the water-absorbing and water-insoluble base material than on/in the water-absorbing and gel-forming base material.   The present invention provides the powdery composition for nasal administration excellent in absorption of the drug from the nasal cavity and having an extremely increased maximum blood concentration comparing a conventional composition for nasal administration even for a drug having a high solubility in water, a drug having a high lipophilicity or a peptide/proteinaceous drug having a large molecular weight.