Patent SG-11201804787U-A (SG)
Title: Human immunodeficiency virus neutralizing antibodies
Inventor: BALAKRISHNAN MINI
IPC: A61K39/395
Filed: 2016-12-14
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau 1111111111111111111111111111111111111111111111111111111111111111111111111111R111111111111111 (10) International Publication Number WO 2017/106346 A2 WIPO I PCT (43) International Publication Date 22 June 2017 (22.06.2017) (51) International Patent Classification: Not classified (21) International Application Number: PCT/US2016/066658 BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KR KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: (22) International Filing Date: 14 December 2016 (14.12.2016) English English (25) Filing Language: (26) Publication Language: (30) Priority Data: 62267652 15 December 2015 (15.12.2015) US (71) Applicant: GILEAD SCIENCES, INC. [US/US]; 333 Lakeside Drive, Foster City, CA 94404 (US). (72) Inventors: BALAKRISHNAN, Mini; c/o Gilead Sci- ences, Inc., 333 Lakeside Drive, Foster City, CA 94404 (US). CARR, Brian A.; do Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404 (US). CORBIN, John; 5816 Mendocino Avenue, Oakland, CA 94618 (US). PACE, Craig S.; c/o Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404 (US). THOMSEN, Nathan D.; c/o Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404 (US) ZHANG, Xue; c/o Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404 (US). (74) Agents: DAMMANN, Yu-Ming et al.; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, California 94404 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, as to applicant's entitlement to apply for and be granted a patent (Rule 4.170) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: without international search report and to be republished upon receipt of that report (Rule 48.2(g)) with sequence listing part of description (Rule 5.2(a)) W O 20 17 / 1063 46 A2 (54) Title: HUMAN IMMUNODEFICIENCY VIRUS NEUTRALIZING ANTIBODIES (57) : The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceut- ical compositions, and methods of use thereof