baber/WOPTO huggingface dataset:
Patent ES-2247288-T3 (ES)
Inventor: HONEGGER WERNER
IPC: B65H39/06
Filed: 2002-04-19
Granted: 2006-03-01
Abstract: Flat articles are gathered on stack supports (2) being conveyed past feed points substantially continuously and one after the other. After the gathering operation, bottom edge zones (13) of the gathered articles are exposed for a further processing operation. The corresponding device includes continuously conveyed stack supports (2) each with an inclined supporting surface (3) and a foot element (4) located in the bottom area of the supporting surface (3). The foot elements are actively connected with the supporting surfaces such that they are capable of being pressed against the supporting surface and of being spaced from the supporting surface. In an exposure zone downstream of the gathering zone (1), stack support structure, which are conveyed in synchronism with the stack supports (2) and substantially in the same direction, and a control device are provided. At the entrance to the exposure zone (1), the stack support structure is arranged so as to be positioned immediately underneath the stack supports and such that, further downstream, the stack support structure moves away from the stack supports (2) in a downwards direction. The control device acts on the foot elements (4) of stack supports (2) conveyed through the exposure zone such that the foot elements are spaced from the supporting surfaces (3) at the entrance to the exposure zone for letting the stacks slide down onto the stack support device, and such that the stacks having slid down onto the stack support device (10) are clamped between the foot element and the supporting surface. The exposed edge zones (13) of the gathered articles can then be processed in a simple way and/or can be taken hold of by further conveying device.
Patent ES-2296893-T3 (ES)
Inventor: MURPHY GREER M
IPC: A61K31/55
Filed: 2002-02-12
Granted: 2008-05-01
Abstract: This invention relates to methods for improving the treatment of major depression in a human patient by genotyping the patient for the gene for apolipoprotein E4 and adapting the further treatment of the patient accordingly depending on the presence or absence of the gene in the patient. The invention also relates to methods for improving the therapeutic response of human patients with major depression by determining the apolipoprotein E genotype of a human patient and administering a noradrenergic transmission enhancing anti-depressant drug, such as mirtazapine, in an amount effective to treat major depression, to those patients who are found to carry the gene for apolipoprotein E4. Also disclosed are methods for improving the therapeutic response of a human patient with major depression comprising administering mirtazapine, in an amount effective to treat major depression, to a human patient who is a carrier of the gene for apolipoprotein E4.
Patent ES-2238560-T3 (ES)
Title: Derivados de piperidina como antagonistas de neuroquinina 1.
Inventor: KOLCZEWSKI SABINE
IPC: A61K31/506
Filed: 2002-01-28
Granted: 2005-09-01
Abstract: Compuestos de la **fórmula** en donde R1 a) es fenilo, no sustituido o sustituido por uno o más sustituyentes seleccionados del grupo R1 que consiste en - halógeno, - trifluorometilo, -piperazinilo, opcionalmente sustituído por un alquilo C1-7, - morfolinilo, - NH-fenilo, - pirrolidinilo, - NH(CH2)n-O-alquilo C1-7, - NR2, - NH(CH2)n-cicloalquilo, - NH(CH2)n-NR2 o es b) morfolinilo, opcionalemente sustituído por uno o dos grupos alquilo C1-7, o es c) piperazinilo, no sustituido o sustituido en la posición -4 por el grupo R1¿ el cual es - alquilo C1-7, - cicloalquilo, - fenilo, - benzoxazolilo, - piridinilo, - pirimidinilo - pirazinilo, - (CH2)n -cicloalquilo, - (CH2)n -fenilo, - (CH2)n ¿hidroxilo, - (CH2)n - CF3, - (CH2)n ¿C(O)-morfolinilo, - (CH2)n- C(O)-N(R)-fenilo, en donde el anillo de fenilo se sustituye opcionalmente por alquilo C1-7 o halógeno.
Patent ES-2261667-T3 (ES)
Inventor: HAGGANDER JAN
IPC: F02K1/00
Filed: 2002-01-09
Granted: 2006-11-16
Abstract: Method and arrangement for providing an outlet nozzle (10) for use in a liquid fuel rocket engine. The nozzle forms a body of revolution having an axis (11) of revolution and a cross section that varies in diameter along said axis. The nozzle has a wall structure having a plurality of mutually adjacent cooling channels, helically extending substantially in parallel from the inlet end (13) of the nozzle to its outlet end (14). The nozzle includes at least two longitudinally arranged sections (10a,10b,10c). A shift between a positive and a negative channel angle in the transition from one section to an adjacent section balances any roll momentum generated by friction of rocket exhausts against the nozzle wall.
Patent ES-2257553-T3 (ES)
Title: Ensayos de sensibilidad a farmacos virales.
Inventor: KALLANDER CLAS
IPC: C12Q1/70
Filed: 2002-06-14
Granted: 2006-08-01
Abstract: Un método para analizar la sensibilidad al fármaco fenotípica en un individuo mamífero infectado por virus con envuelta analizando en una polimerasa introducida en un virus con envuelta recuperado de una muestra biológica de dicho individuo, que comprende las etapas de: a) añadir un agente inactivante de enzima seleccionado a partir de agentes modificantes de cisteína, tales como 5, 5¿-ditiobis-(ácido 2-nitrobenzoico), a la muestra para inactivar la actividad de la polimerasa distinta a la presente en el virión con envuelta, b) purificar y concentrar el virus con envuelta eliminando anticuerpos que bloquean la actividad de la enzima, inhibidores de la actividad de la enzima endógenos, fármacos antivirales y los agentes que inactivan a la enzima, c) lisar las partículas virales para liberar a la polimerasa, d) recuperar la polimerasa viral purificada y concentrada que es el resultado de b) y c) y determinar el perfil de sensibilidad al fármaco del individuo a partir de la enzima recuperada usando ensayos enzimáticos sensibles.
Patent ES-2264484-T3 (ES)
Inventor: WALLS JAMES
IPC: G01K1/08
Filed: 2002-05-16
Granted: 2007-01-01
Abstract: A disposable, molded probe cover for use with an electronic thermometer is disclosed. The probe cover comprises an elongated hollow body made of a plastic material which defines a distal end and a proximal end. The distal end of the body has a convex-shaped surface that defines a lubrication well adapted to hold a lubricant therein, while the proximal end forms an opening. The opening communicates with a chamber that extends the entire length of the body and is sized and shaped to receive a probe of the electronic thermometer. To vent air trapped in the chamber during insertion of the probe into the probe cover, the chamber is provided with an axial ridge defined along a portion of the chamber for allowing air trapped at the distal end of the chamber to escape the probe cover through the electronic thermometer. A plurality of detents are also provided along the chamber proximate the opening for securely engaging the probe and establishing a fluid tight seal between the probe cover and the thermometer. When the probe cover is inserted into a patient body cavity, the lubricant spreads outwardly from the lubrication well and spreads over the exterior surface of the probe cover.
Patent ES-2259094-T3 (ES)
Inventor: MORRIS JOHN ALAN
IPC: B65D83/14
Filed: 2002-07-24
Granted: 2006-09-16
Abstract: Top cone for an aerosol can, including a formed metal sheet extending around a longitudinal central axis, and having a contour that includes, as seen in longitudinal cross section from the top downward, a top section intended for holding a valve cap, a cone section connected to the top section and leading to a countersink section and a flange section. The countersink section is essentially U-shaped whereby the outer leg of the essential U-shape, that is the leg being furthest removed from the central axis, is bent away from the central axis to form the flange section, and which cone section has a continuously increasing transversal diameter, wherein the top cone comprises strengthening means for strengthening the countersink section against pivoting toward the central axis.
Patent ES-2278057-T3 (ES)
Inventor: WILSON LARRY J
IPC: F16B39/24
Filed: 2002-09-06
Granted: 2007-08-01
Abstract: The fastener assembly comprises a torquing member and a clamping pressure member assembled together on a common access. The torquing member has annual threads formed around the axis. An annular bearing surface extends around the axis on one end of the member. The clamping pressure member has an annular bearing surface formed around the axis on one end and an annular clamping surface extending around the axis on an opposite end. The annular bearing surface of the torquing member includes a first series of helically inclined surface segments having substantially the same pitch axis as the threads and a second series of helically inclined surface segments having the same pitch axis as the threads but a pitch equal to or greater than that of the threads, with an opposite incline. The annual bearing surface on the clamping pressure member includes a first series of helically inclined surface segments having substantially the same pitch axis as the threads, and a second series of helically inclined surface segments having substantially the same pitch and direction as said equal or greater pitch. Helically inclined bearing surfaces on the torquing member and the clamping pressure member engage each other in locking relationship.
Patent ES-2341762-T3 (ES)
Inventor: KREBS MICHAEL
IPC: C08G18/10
Filed: 2002-10-02
Granted: 2010-06-28
Abstract: The present invention describes reaction products from 2,4′-diphenylmethane diisocyanate with a content of at least 95 wt. % of 2,4′ isomer with at least one polyether-polyol and/or polyalkylene glycol with a molecular weight of less than 1,000 and/or one crystalline or partly crystalline or vitreously amorphous polyester-polyol and optionally polyester-polyols and/or polyether-polyols which are liquid at room temperature and have molecular weights of greater than 1,000 can be converted into adhesive compositions which have a very low content of monomeric diisocyanate of less than 0.5, preferably less than 0.25 wt. %. Such hot melt adhesive compositions have a high melt stability and a low viscosity, in addition to the low content of monomeric diisocyanate.
Patent ES-2272787-T3 (ES)
Inventor: THOMMES GLEN ANTHONY
IPC: G03C1/76
Filed: 2002-11-27
Granted: 2007-05-01
Abstract: A radiation curable resin composition suitable for making three dimensional objects comprises at least one epoxy compound, and a cationic photoinitiator, wherein the resin composition has a first color or no color before cure and wherein a three dimensional object made from the resin by subjecting the resin to radiation shows a second color which is different from the color of the resin composition before cure.
Patent ES-2289185-T3 (ES)
Title: Produccion de peptidos y proteinas por acumulacion en cuerpos proteicos derivados del reticulo endoplasmico en plantas.
Inventor: LUDEVID MUGICA MARIA DOLORES
IPC: C12P21/02
Filed: 2002-08-05
Granted: 2008-02-01
Abstract: Una secuencia de ácido nucleico que comprende: una primera secuencia de ácido nucleico que contiene la secuencia de nucleótidos que codifica la proteína gamma-zeína, o un fragmento de la misma que contiene una secuencia de nucleótidos que codifica una secuencia de aminoácidos capaz de dirigir y retener una proteína en el retículo endoplásmico (ER) de una célula vegetal; una segunda secuencia de ácido nucleico que contiene una secuencia de nucleótidos que codifica una secuencia de aminoácidos que se puede escindir específicamente por medios enzimáticos o químicos; y una tercera secuencia de ácido nucleico que contiene la secuencia de nucleótidos que codifica un producto de interés; donde el extremo 3'''''''' de dicha primera secuencia de ácido nucleico está unido al extremo 5'''''''' de dicha segunda secuencia de ácido nucleico y el extremo 3'''''''' de dicha segunda secuencia de ácido nucleico está unido al extremo 5'''''''' de dicha tercera secuencia de ácido nucleico.
Patent ES-2300513-T3 (ES)
Title: Derivados de fenilpirimidinas sustituidas por un grupo piperazinilo, utiles en el tratamiento o en la prevencion de trastornos del sistema nervioso central.
Inventor: MILLER ALISTAIR AINSLIE
IPC: A61K31/495
Filed: 1989-12-06
Granted: 2008-06-16
Abstract: Una pirimidina de fórmula (I): (Ver fórmula) en la que R1 es piperazinilo; R2 es amino; R3 se selecciona entre trifluorometilo, hidrógeno, metilo, benciloximetilo, metoximetilo y metiltiometilo; R4 es cloro; al menos uno de R5, R6 y R7 es cloro y los restantes de R5, R6 y R7 se seleccionan entre hidrógeno y cloro en el caso de R5 y R7 y entre hidrógeno, cloro y nitro en el caso de R6; y R8 es hidrógeno; y sales de adición de ácidos farmacéuticamente aceptables de la misma.
Patent ES-2299639-T3 (ES)
Inventor: HASSEBERG HANS-ALBRECHT DR
IPC: A23K1/18
Filed: 2003-04-02
Granted: 2008-06-01
Abstract: The invention relates to active compound formulations for animal nutrition of amino acids, vitamins, enzymes and pigments, which are suitable for providing the active compounds in protected form for the nutrition of stock animals, in particular ruminants, and a process for the preparation of these protected active compound formulations.
Patent ES-2298452-T3 (ES)
Inventor: VOSTEEN BERNHARD PROF DR
IPC: B01D53/64
Filed: 2003-07-15
Granted: 2008-05-16
Abstract: Mercury is removed from flue gases of high-temperature plants by feeding bromine and/or a bromine compound to a multi-stage furnace and/or to the flue gas, and subjecting the flue gas to a multi-stage clean-up. The combustion takes place in the presence of a sulfur compound, particularly sulfur dioxide, with or without the addition of sulfur and/or a sulfur compound and/or a mixture of various sulfur compounds. The removal of mercury from flue gases of high-temperature plants, comprises feeding bromine and/or a bromine compound and/or a mixture of various bromine compounds to a multi-stage furnace and/or to the flue gas in a plant section downstream of the furnace, the temperature during the contact of the bromine compound with the flue gas being >= 500[deg]C, preferably >= 800[deg]C. The combustion takes place in the presence of a sulfur compound, particularly sulfur dioxide, with or without the addition of sulfur and/or a sulfur compound and/or a mixture of various sulfur compounds. The flue gas is subjected to a multi-stage clean-up comprising a wet scrubber and/or a dry clean-up.
Patent ES-2352688-T3 (ES)
Inventor: WOLFSTEINER PETER DR
IPC: B60T17/08
Filed: 2003-07-24
Granted: 2011-02-22
Abstract: The spring storage cylinder has a spring storage piston (3) in a housing (2), a piston rod (4), a spring (5) and a cavity (7) which has a pressure connection (6). An emergency release device (8, 9, 10, 11, 12, 13, 14) can break the power flux between the piston and its rod. This device can be released by an operating member (24) which releases it when the pressure at the pressure connection falls below a set level.
Patent ES-2239297-T3 (ES)
Title: Dispersiones acuosas de particulas hibridas de polimeros de adicion de poliuretano para su empleo en composiciones de revestimiento.
Inventor: WILLIAMS NEAL
IPC: C08G18/08
Filed: 2003-11-18
Granted: 2005-09-16
Abstract: Dispersión acuosa de partículas híbridas de polímero de adición de poliuretano, partículas que comprenden: i) un polímero de poliuretano, ii) un copolímero de adición de monómeros copolimerizables etilénicamente insaturados, siendo el polímero de poliuretano i) el producto de reacción de a) un poliisocianato aromático esencialmente libre de partes isocianato impedidas estéricamente, b) un poliisocianato alifático, c) un compuesto que contiene dos partes hidroxilo reactivas con las partes isocianato de a) y b), d) un compuesto que contiene como mínimo una parte dispersante y como mínimo una parte reactiva con las partes isocianato de a) y b), e) un compuesto prolongador de cadena, caracterizada porque la relación entre la cantidad total de partes isocianato del poliisocianato aromático y la cantidad total de partes reactivas con isocianato de c) y d) es de 0, 50 a 1, 45.
Patent ES-2549401-T3 (ES)
Title: Procedimiento para la preparación de ésteres alquílicos del ácido 2,2-dicloro- o dibromo-fenilacético
Inventor: KRICH SYLVIA
IPC: C07C69/65
Filed: 2003-03-10
Granted: 2015-10-27
Abstract: Procedimiento mejorado para la preparación de ésteres alquílicos del ácido 2,2-dicloro- o -dibromo-fenilacético de la fórmula**Fórmula** en la que X es Cl o Br, n puede ser un número entero de 1 hasta 5, R significa hidrógeno, alquilo de C1-C8, arilo, heteroarilo, alcoxi de C1-C8, ariloxi o halógeno y R1 significa alquilo de C1-C8, caracterizado por que se hace reaccionar un 2,2-dicloro- o dibromo-fenilacetonitrilo de la fórmula**Fórmula** en la que X, n y R se definen como más arriba, en 0,8 a 2 moles de agua por cada mol de un nitrilo de la fórmula (II), de 1 a 8 moles de un alcohol de la fórmula R1OH (III) en la que R1 es como se ha definido más arriba, por cada mol del nitrilo de la fórmula (II) y en presencia de 1 a 3 moles de HCl o HBr por cada mol del nitrilo de la fórmula (II), eventualmente en presencia de un disolvente que es inerte en las condiciones de la reacción, para dar el correspondiente éster alquílico del ácido 2,2-dicloro- o dibromo-fenilacético de la fórmula (I), estando situada la temperatura de reacción en la primera fase de la conversión química en 35 hasta 55ºC y en la segunda fase en 60 hasta 100ºC, después de lo cual, tras de haberse efectuado la conversión química de la mezcla de reacción, se enfría a 20 hasta 40ºC y se diluye con agua, y se aísla el correspondiente éster alquílico del ácido 2,2-dicloro- o dibromo-fenilacético de la fórmula (I).
Patent ES-2290440-T3 (ES)
Inventor: SILVA JAMES MANIO
IPC: C08G63/64
Filed: 2003-03-11
Granted: 2008-02-16
Abstract: Thermally stable block copolyestercarbonates comprising chain members derived from at least one dihydroxy-substituted aromatic hydrocarbon moiety and at least one aromatic dicarboxylic acid moiety, said polymer being substantially free of anhydride linkages linking at least two mers of the polyester chain segments, are prepared by a method comprising the steps of: (a) preparing a hydroxy-terminated polyester intermediate comprising structural units derived from at least one dihydroxy-substituted aromatic hydrocarbon moiety and at least one aromatic dicarboxylic acid moiety; and (b) conducting a reaction of the polyester intermediate with phosgene in a reaction mixture comprising water, a substantially water-immiscible organic solvent, and a base, wherein base and phosgene are added simultaneously to the reaction mixture at a substantially constant molar ratio of base to phosgene for a time period of at least about 60% of the total amount of phosgene added.
Patent ES-2331567-T3 (ES)
Inventor: WALLACE MICHAEL P
IPC: A61F2/06
Filed: 2003-04-10
Granted: 2010-01-08
Abstract: The present invention is directed to systems for occluding an aneurysm having an aneurysmal neck and an aneurysmal inner wall. Generally, a device in accordance with the present invention includes a mesh-like structure that is integrally composed of a shape-memory alloy such as NiTi. The device is deployed within the aneurysm through the aneurysmal neck. The device is configured to be in a deployed state and an undeployed state, and is configured to transition from the undeployed state to the deployed state by exposure to a higher temperature and/or by being unconstrained. The device may function to retain finer vaso-occlusive devices such as vaso-occlusive coils and/or embolic liquids. Furthermore, the device itself may function as a vaso-occlusive device.
Patent ES-2334219-T3 (ES)
Inventor: BLEINER THOMAS
IPC: F21Y101/00
Filed: 2003-07-01
Granted: 2010-03-08
Abstract: Optical signalling device ( 1, 20, 30 ) for vehicles (A), comprising: a support element ( 2 ) fitted to the abovementioned vehicle (A), a revolving element ( 3 ) arranged on the support element ( 2 ) and coupled to drive means ( 4 ) able to cause rotation thereof and one or more optical signalling elements ( 8 ) associated with the revolving element ( 3 ) and electrically connected to an electric power source able to illuminate them. Each optical signalling element ( 8 ) comprises one or more laser light generators/emitters ( 9 ).
Patent ES-2271620-T3 (ES)
Inventor: LANFRANCHI MARIO
IPC: B65G47/14
Filed: 2003-03-04
Granted: 2007-04-16
Abstract: Device for automatically adjusting vertically directing and aligning means in dependence on said containers size. The directing means are formed by a plurality of cradles ( 5 ) and the aligning means are formed by a corresponding plurality of discharge channels ( 6 ), both means are provided with movable parts ( 10, 35 ), respectively, adjustable in dependence on plastic containers size. The device provides at least one control member located on the machine outer stationary cylindrical wall ( 3 ) and adapted to engage movable parts ( 10, 35 ) of cradles and discharge channels, respectively, while the inner hopper holding bulk plastic containers rotates. Movable parts ( 10, 35 ) respectively, act on a movable fin ( 26 ) that adjusts the cradle cross-section and a movable rear wall or back ( 33 ) of the discharge channel.
Patent ES-2279202-T3 (ES)
Title: Arquitectura electrica de un dispositivo de seleccion de velocidades para una caja de cambios automatica.
Inventor: ARDUINI ALAIN
IPC: F16H59/02
Filed: 2003-10-20
Granted: 2007-08-16
Abstract: Arquitectura eléctrica de un dispositivo electrónico de selección de velocidades para caja de cambios automática o robotizada, que comprende, especialmente, una palanca cerca del volante, un módulo electrónico de selección de velocidades que gobierna el accionador de selección de velocidades de la caja de cambios automática y un módulo de mando de la caja de cambios automática, caracterizada porque la palanca (1) y el módulo (30) de selección de velocidades están conectados por una conexión eléctrica específica, realizada por una red CAN privativa (Cp) con un protocolo particular, y porque la conexión entre el citado módulo (30) de selección de velocidades y el módulo (25) de mando de la caja de cambios automática, está asegurada por la red CAN multiplexada (Cg) del vehículo, y la conexión entre el módulo (30) de selección de velocidades y el accionador (19) de selección de relación de transmisión de la caja de cambios automática, está asegurada por una red de cable.
Patent ES-2305563-T3 (ES)
Inventor: EDWARDS PAUL JOHN
IPC: A61K31/4166
Filed: 2003-09-24
Granted: 2008-11-01
Abstract: This invention relates to pyrazole derivatives of formula (I)or pharmaceutically acceptable salts, solvates or derivative thereof, wherein R' to R4; ;ark defined in the description, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such the compounds of the present invention are useful in the treatment of a variety of disorders including those in which the inhibition' of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodificiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).