Patent AU-2020324193-B2 (AU)
Title: Biosensor and method for determining dimension of counter electrode and prolonging usage lifetime of the same
Inventor: HUANG CHUN-MU
IPC: G01N27/06
Filed: 2020-08-03
Granted: 2022-04-21
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) 
(19) World Intellectual Property 
(1) Organization11111111111111111111111I1111111111111i1111liiiii 
International Bureau (10) International Publication Number 
(43) International Publication Date W O 2021/023153 Al 
11 February 2021 (11.02.2021) W IPO I PCT 
(51) International Patent Classification: TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, 
G01N 27/06 (2006.01) KM, ML, MR, NE, SN, TD, TG).  
(21) International Application Number: PublishedPCT/CN2020/106571 Pulshd 
- with international search report (Art. 21(3)) 
(22) International Filing Date: 
03 August 2020 (03.08.2020) 
(25) Filing Language: English 
(26) Publication Language: English 
(30) Priority Data: 
62/882,162 02 August 2019 (02.08.2019) US 
62/988,549 12 March 2020 (12.03.2020) US 
(71) Applicants: BIONIME CORPORATION [CN/CN]; No.  
100, Sec. 2, Daqing Street, South District, Taichung City, 
Taiwan 40242 (CN). BIONIME USA CORPORATION 
[US/US]; 1450 E. Spruce Street, Bldg. B, Ontario, Califor
nia 91761-8314 (US).  
(72) Inventors: HUANG, Chun-Mu; No. 100, Sec. 2, Daqing 
Street, South District, Taichung City, Taiwan 40242 (CN).  
CHEN, Chieh-Hsing; No. 100, Sec. 2, Daqing Street, 
South District, Taichung City, Taiwan 40242 (CN).  
(74) Agent: CCPIT PATENT AND TRADEMARK LAW 
OFFICE; 8thFloor, Vantone New World Plaza, 2 Fucheng
menwai Street, Xicheng District, Beijing 100037 (CN).  
(81) Designated States (unless otherwise indicated, for every 
kind of national protection available): AE, AG, AL, AM, 
AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, 
CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, 
DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, 
HR, HU, ID, IL, IN, IR, IS, IT, JO, JP, KE, KG, KH, KN, 
KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, 
ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, 
NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, 
SA, SC, SD, SE, SG, SK, SL, ST, SV, SY, TH, TJ, TM, TN, 
TR, TT, TZ, UA, UG, US, UZ, VC, VN, WS, ZA, ZM, ZW.  
(84) Designated States (unless otherwise indicated, for every 
kind of regional protection available): ARIPO (BW, GH, 
GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, 
UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, 
TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, 
EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, 
MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, 
(54) Title: BIOSENSOR AND METHOD FOR DETERMINING DIMENSION OF COUNTER ELECTRODE AND PROLONGING 
flUSAGE LIFETIME OF THE SAME 
en (57) Abstract: A biosensor for measuring a physiological signal representative of a physiological parameter associated with an analyte.  
The biosensor (100) includes a working electrode (120) and a counter electrode (130). The counter electrode (130) includes silver and 
silver halide having an initial amount, wherein the initial amount is determined by the following steps of defining a required consumption 
range of the silver halide during at least one of the measurement periods performed by the biosensor (100); and determining the initial 
amount based on a sum of an upper limit of the required consumption range and a buffer amount, so that a required replenishment 
CA amount range of the silver halide during the replenishment period is controlled to be sufficient to maintain an amount of the silver 
halide within a safe storage range.