baber/WOPTO huggingface dataset:
Patent DK-169152-B1 (DK)
Inventor: RUTTER WILLIAM J
IPC: C12N1/16
Filed: 1991-06-14
Granted: 1994-08-29
Abstract: The present invention relates to synthesis of HBsAg in yeast. Yeast expression vectors comprising a yeast promoter, ADHI, have been constructed. The region of the HBV genome coding for the S-protein, excluding a possible 163 amino acid presequence, has been transferred to the yeast expression vector. Using the described yeast vector, the successful synthesis of HBsAg by yeast has been achieved. The product is antigenic (reactive with anti-HBsAg), and a substantial portion is found associated with particles identical in electron microscopic appearance to those found in the serum of HBV-infected patients and in Alexander cells but having a smaller particle size diameter. The HBsAg synthesized by yeast has identical sedimentation behavior to purified, naturally-occurring HBsAg particles purified from Alexander cells as measured by sucrose gradient sedimentation. The present invention demonstrates synthesis and assembly of a higher ordered multi-component structure resulting from expression of a heterologous DNA coding segment in a microorganism.
Patent DK-172178-B1 (DK)
Inventor: KAPMEYER WOLFGANG
IPC: G01N33/546
Filed: 1988-05-06
Granted: 1997-12-15
Abstract: The method for detecting or determining a participant in a particle-enhanced immunological reaction by a nephelometric, turbidimetric or particle-counting method comprises carrying out the detection or determination in the presence of an antiserum which contains no antibodies which are specific for one of the immunological reactants.
Patent DK-167661-B1 (DK)
Inventor: VELASCO VICENTE SANCHEZ
IPC: B23B41/00
Filed: 1986-12-30
Granted: 1993-12-06
Abstract: The invention refers to a device for the obtention of annular cavities at the bottom of drills made on surfaces of any kind. 
<??>The apparatus, which may be coupled to any motor element as a conventional drilling machine, incorporates an axle of a considerable length, edged in a cutter, provided with a rotating movement, which axle is housed in a cylindrical piece, in a sharply eccentric mode, said piece also receiving a rotating element with respect to the fixed body, of the apparatus in its whole, so that the cutter and the fixed body remain perfectly coaxial when introduced in the drill, and by rotating the cutter at a high speed, a slow rotating movement of the casing piece determines the progressive eccentricity of the cutter with respect to the fixed body, for the obtention of the annular cavity which is pursued. On the fixed body itself, in parallel with the axle of the cutter, and to the moving piece which houses it, is set forth a conduct for the refrigeration water of said cutter.
Patent FI-103016-B1 (FI)
Inventor: MARSAN MARIO STEPHEN
IPC: A61F13/56
Filed: 1990-10-29
Granted: 1999-04-15
Abstract: A disposable, absoroent diaper (20) comprising a topsheet (38), a liquid impervious backsheet (40) associated with the topsheet, and an absorbent core disposed between the topsheet and the backsheet, wherein the absorbent core (41) has a dusting layer (76) of mechanical pulp fibers, a continuous primary layer of mechanical pulp fibers containing from about 8% to about 60%, on a total primary layer (74) dry weight basis, of discrete particles of polymeric gelling material, and a water-permeable core reinforcing layer (72) disposed between the dusting layer and the primary layer. The mechanical pulp fibers, preferably chemithermomechanical pulp fibers, have an average fiber length of at least about 1.9 mm and are in a highly disintegrated condition. <IMAGE>   <IMAGE>
Patent FI-104165-B1 (FI)
Inventor: MALRIC BERNARD
IPC: C09K3/18
Filed: 1993-08-13
Granted: 1999-11-30
Abstract: A concrete surface having at least a residual amount of sodium fluorophosphate. A method to reduce scaling due to freezing and thawing is also disclosed. The method comprises contacting the surface of a concrete with a system containing at least sodium fluorophosphate. The sodium fluorophosphate closes the pores to water and other foreign matter.
Patent IE-36056-B1 (IE)
Title: New antibiotic
IPC: A23K20/195
Filed: 1971-08-13
Abstract: 1325200 The antibiotic MYC 8003 KONINKLIJKE NEDERLANDSCHE GIST-EN SPIRITUS - FABRIEK NV 13 Aug 1971 [14 Aug 1970] 39367/70 Heading C2A An antibiotic designated MYC 8003 is a solid yellow, salt forming weak acid containing the elements C, H, O and N, and has an optical rotation [α]<SP>22</SP> D of - 60 degrees (1% methanolic solution), is poorly soluble in carbon tetrachloride and benzene, soluble in chloroform, methyl isobutyl ketone, butyl acetate, ethyl acetate, methanol and alkaline solutions, gives a slightly positive reaction in the aromate test, forms a red colour with concentrated sulphuric acid, a dark brown colour in the Pauly reaction, a dark red colour and turbidity with ferric chloride, and a precipitate with bromine water, gives a gas production at 135‹ C. and further gas production at 152‹ C. and decomposes at 164‹ to 174‹ C., has ultraviolet maxima at 233, 276, 286 and 327 nm. and infra-red absorption maxima at 810, 860, 940, 980, 1090, 1215, 1355, 1455, 1540, 1650, 2930, 2970 and 3400 cm.<SP>-1</SP> and salts thereof. A process for the production of this antibiotic comprises aerobic cultivation of Streptomyces ramocissimus (C.B.S. 190.69) or antibiotic MYC 8003 producing mutants thereof, in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and separating the antibiotic formed during the cultivation. A method of accelerating the growth of a domestic animal comprises feeding to the animal a feedstuff containing a growthpromoting amount of the antibiotic MYC 8003 or a salt thereof.
[GB1325200A]
Patent IE-35724-B1 (IE)
Title: Textile finishing
IPC: D06M13/50
Filed: 1971-10-13
Abstract: 1372694 Flame-proofing textiles IWS NOMINEE CO Ltd 19 Oct 1971 [22 Oct 1970 29 Jan 1971] 50324/70 and 3516/71 Headings D1B and D1P Natural or synthetic polyamides e.g. nylon, wool, alpaca, cashmere, mohair, vicuna, guanaco, camel hair, or llama or blends thereof with polyester or cotton or each other are given flame resist properties by treatment with an aqueous solution or paste of a watersoluble complex formed from an organic chelating agent or fluoride ions in which titanium forms part of a complex anion. The complex may be formed in situ in the treating solution. Specified organic chelating agents are oxalic, citric and tartaric acid. Specified sources of fluoride ions are alkali metal and ammonium fluorides and bifluorides and sodium and ammonium fluoroborate. The complex is formed by reacting TiCl 4 with the complexing agents: A specified complex is potassium titanium oxalate. Other flame retardants e.g. Sb 2 F 3 , SbCl 3 antimony potassium tartrate and aluminium compounds e.g. Al 2 (SO 4 ) 3 and AlCl 3 water repellents e.g. fluorocarbon resins, dyes e.g. acid levelling, 1:1-premetallised and reactive dyes, foaming, thickening and wetting agents and HCI, formic and sulphuric acids for PH control may be added. Treatment may be carried out at 20-130‹C. Acid milling may be applied before flame resist treatment and chrome dyes after such treatment. Undyed wool is treated with an alkali metal or ammonium fluoride or bifluoride optionally with a reducing agent e.g. sodium metabisulphite or sodium form aldehyde sulphoxylate to remove discolouration due to the flame proofing treatment. The polyamide may be in the form of a yarn, fleece, noil, garment (woven or knitted) carpet or wool sheepskin. The flame resist process may also impart soil resist properties. Fluorocarbon resins applied are cured.
[GB1372694A]
Patent IE-33838-B1 (IE)
Title: Penicillin derivatives
IPC: A23K20/195
Filed: 1969-11-03
Abstract: 1283099 Penicillins AMERICAN HOME PRODUCTS CORP 6 Nov 1969 [20 Nov 1968 (2)] 54389/69 Heading C2A Novel 6 - (1 - aminocyclopentene - 1 - carboxamido) penicillanic acids of formula (A) and their non-toxic salts, wherein Z is -NHR<SP>1</SP> or a protected amino group, R<SP>1</SP> is H, C 1 -C 7 alkyl or phenyl (C 1 -C 7 ) alkyl, and the dotted line represents a second bond in one of the two designated positions, are prepared by acylating 6-amino-penicillanic acid or its salt or silyl or silenyl derivative with an acid of formula or a functional acylating derivative thereof, and optionally removing the amino - protecting group. The compounds (A) above wherein Z is NHR<SP>1</SP> may be condensed with an aldehyde or ketone of formula R<SP>2</SP>R<SP>3</SP>CO to give novel 6-(4-oxo-1,3- diazaspiro[4,4]nonen - 3 - yl) penicillanic acids of formula (B) or their non-toxic salts, wherein R<SP>2</SP> and R<SP>3</SP> are each H, C 1 -C 7 alkyl or phenyl, or when taken together with the carbon atom to which they are attached form a C 3 -C 7 cycloalkyl ring, and R<SP>1</SP> and the dotted line are as defined above. The preferred acylating agent is the N-carboxy-anhydride of the acid, which is a 3 - oxa - 1 - azaspiro[4,4]nonene - 2,4 - dione of formula wherein R<SP>1</SP> is as above. Pharmaceutical compositions having antibacterial activity against gram-positive and gram-negative bacteria comprise a penicillin of formula (A), wherein Z is -NHR<SP>1</SP> as defined above or of formula (B), or a non-toxic salt thereof together with a pharmaceutically acceptable carrier.
[GB1283099A]
Patent IE-53399-B1 (IE)
Title: Edible fat process
IPC: C11C3/10
Filed: 1982-07-08
Abstract: The process combines selective rearrangement with fractionation to provide a fat with improved glyceride symmetry for use as hard butters. The rearrangement is carried out in contact with an enzyme catalyst which is selectively reactive in the 1- and 3-positions only of glycerides. Fractionation may be by crystallisation optionally using a suitable solvent.
Patent IE-39731-B1 (IE)
Title: Improvements in or relating to multiple jet aerotors
IPC: B01F33/40
Filed: 1974-08-06
Abstract: A multiple jet aerator module or header which is formed substantially completely of fiber glass and which includes a right-circular tubular sheet-form liquid duct and a right-semicircular tubular sheet-form air duct having a radius substantially less than the radius of the liquid duct. Molded fiber glass liquid nozzles are located along the length of the liquid duct and a corresponding number of liquid-air nozzles are located along the length of the air duct in register with the liquid nozzles.
[US3897000A]
Patent IE-41593-B1 (IE)
Title: Packages and methods of forming the same
IPC: B65D85/76
Filed: 1975-08-01
Abstract: 1515134 Packages L D SCHREIBER CHEESE CO INC 28 July 1975 [22 Aug 1974] 31474/75 Heading B8C A package including individually sealed compartments each containing a product such as food comprises at least one stack of portions 12, 13 of the product, and sheets 15 preferably of substantially oxygen-impermeable material interleaving the product portions 12, 13, the sheets 15 preferably being releasably sealed to a backing board 11 so that they can be pulled away to dispense the portions 12, 13 in turn. The sheets 15 may be of laminated structure, including, e.g. a nylon, polyethylene or polyester substrate, or of metal, and each compartment may be evacuated or flushed with a preservative gas; the board may be of polyester, polyvinylchloride or coated material. The board 11 may be flat, with a series of sheets 15 attached to one or both faces, Fig. 2 or Fig. 3 (not shown), or the sheets 15, which may be vacuum moulded, may be attached to a flange 74 of a cupped board 71, Fig. 7. The edges of the sheets 15 may each be secured directly to the board, Fig. 7, or to each other, Fig. 2.
Patent IE-48942-B1 (IE)
Title: 3-unsubstituted-3-cephem compounds
IPC: A61K31/546
Filed: 1979-09-19
Abstract: Antibacterial compounds represented by the following formula including their pharmaceutically acceptable salts and esters; process for preparing them; pharmaceutical preparation comprising them; and method for combating infections by administering them:  (wherein Hal is halogen; R1 is hydrogen or an amino-protecting group; R2 is alkyl; and R3 is hydrogen or a carboxy-protecting group.
Patent IE-65878-B1 (IE)
Title: Mixed metal layered hydroxide-clay adducts as thickeners for water and other hydrophylic fluids
Inventor: BURBA JOHN L III
IPC: C01B13/14
Filed: 1986-07-03
Abstract: Novel compositions useful as fluid gelling agents, especially for use in subterranean applications such as drilling fluids, are prepared by reacting an aqueous dispersion of a clay, such as bentonite, with an aqueous gel of a monodispersed mixed metal layered hydroxide.
Patent IE-48952-B1 (IE)
Title: Method and apparatus for inserting weatherstrip or the like in a groove
IPC: E06B7/23
Filed: 1979-10-02
Abstract: An apparatus and method for feeding a flexible elongate member, e.g. pile weatherstrip, into a groove in an elongated member, the apparatus being capable of being driven by an electric motor or drill and including a pair of rollers (11,17) defining a nip through which the pile is driven into an outlet guide (43) with which the groove in the elongated member is alinged atthe downstream-end thereof. It is preferred that two sets of roller nips are provided, there being a common roller for each nip and there being an inlet guide (39) to direct the pile weatherstrip into a first nip, and an intermediate guide (41) to direct the weatherstrip from the first nip to the second nip and hence into the outlet guide (43).
Preferably, the roller common to each pair is driven via a toothed belt, and the other two rollers can be moved towards or away from said common roller. Preferably, this roller has a grooved periphery to receive the pile of the weatherstrip and all the rollers are knurled.
Patent IE-41939-B1 (IE)
Title: Accumulator batteries
IPC: H01M50/147
Filed: 1975-11-18
Abstract: 1528934 Battery cases COMPAGNIE EUROPEENNE D'ACCUMULATEURS 30 Oct 1975 [19 Nov 1974 1 July 1975] 45075/75 Heading H1B The plates of a battery are held in position by horizontal members 18 which are thermowelded to the case 1 or partitions in the case together with the cover 10. The members may be of T, or angle section, and they may extend across the battery in either direction (Figs. 2 to 5) in which case they have holes for electrolyte.
Patent IE-47701-B1 (IE)
Title: Amine derivatives,their preparation and pharmaceutical compositions containing them
IPC: C07C301/00
Filed: 1978-12-21
Abstract: The invention relates to compounds of the general formula (I) and physiologically acceptable salts, N-oxides, hydrates and bioprecursors thereof, in which Y represents =0, =S, =CHNO2 or =NR3 where R3 represents hydrogen, nitro, cyano, lower alkyl, aryl, lower alkylsulphonyl or arylsulphonyl; R1 and R2, which may be the same or different, each represent hydrogen lower alkyl, cycloalkyl, lower alkenyl, aralkyl, hydroxy, lower trifluoroalkyl, lower alkyl substituted by hydroxy, lower alkoxy, amine, lower alkylamino or dialkylamino, or R1 and R2 together with the nitrogen atom to which they are attached form a 5 to 7 membered heterocyclic ring which may contain other heteroatoms or the group where R4 represents hydrogen or lower alkyl; Q represents a furan or thiophen ring in which incorporation into the rest of the molecule is through bonds at the 2- and 5-positions, or a benzene ring in which incorporation into the rest of the molecule is through bonds at the 1- and 3- or 1- and 4-positions; X represents-CH2-,-O-or-S-; n represents zero, 1 or 2; m represents 2, 3 or 4; Alk represents a straight chain alkylene group of 1 to 3 carbon atoms; (except that n is not zero when X is oxygen and Q is a furan or thiophen ring system) q represents 2, 3, or 4 or can additionally represent zero or 1 when E is a -CH2-group; p represents zero, 1 or 2; E represents-CN2-,-O- or -S-; and Z represents a monocyclic 5 or 6 membered carbocyclic or heterocyclic aromatic ring which may be optionally substituted by one or more groups or Z represents the group where Q' represents any of the rings defined for Q; Alk' represents any of the groups defined for Alk: and R5 and R6, which may be the same or different, each represent any of the groups defined for R1 and R2; (except that p is not zero when E is oxygen and Q' or Z is a furan or thiophen ring system. The compounds of formula (I) show pharmacological activity as selective histamine H2-antagonists.
Patent IE-41530-B1 (IE)
Title: New phenyl carbamates
IPC: C07D317/24
Filed: 1974-12-13
Abstract: New phenyl carbamates of the formula (I) wherein R1 and R2 each represent hydrogen, C1-C4-alkyl, chlorine or bromine, R3 and R4 each represent methyl, or together they represent -CH2-CH2-,-CH2-CH2-CH2-, , , , , , , , or . are disclosed, processes for their production and their use in pest control.
Patent IE-65374-B1 (IE)
Title: Substituted sulfonamides process of preparation and medicaments containing them
Inventor: LARDY CLAUDE
IPC: C07D233/54
Filed: 1991-07-30
Abstract: New substituted sulphonamides, their salts, complexes, esters and amides which are physiologically acceptable, denoted by the formula <IMAGE>  in which:   R1 is an aryl radical or a heterocyclic ring, optionally (poly)substituted; R2 and R3 are different; one of the two denotes W, the other is hydrogen, halogen, trifluoromethyl, alkyl, cycloalkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, acyl, thioacyl, hydroxyl, optionally (poly)substituted amine, nitro, nitrile, azide or aryl; W is a -Z-Ar-(CH2)q-A group in which A is CO2H or a group capable of being hydrolysed to CO2H, SO3H, PO3H, a heterocyclic ring, an acyl radical, an oxoalkylcarboxylic radical or a primary alcohol; q is 0,1,2,3 or 4; Ar is an aryl radical or an aromatic heterocyclic ring, optionally substituted by a radical R7; Z is oxygen, CH2 or a bond; R4-7 take simultaneously or independently the values of R2-3, except W; Y is a -(CH2)s-B-(CH2)t- group; s and t are 0,1 or 2; B is an oxygen atom, oxidised or unoxidised sulphur, optionally substituted nitrogen, a (thio)carbonyl functional group, a heterocyclic ring, an alkylene radical, an optionally substituted alkyl radical or a bond;   n is 0 or 1.   Application of these thromboxane A2 receptor antagonist compounds with a long period of activity as antithrombotic and antiasthmatic medications.
Patent IE-54762-B1 (IE)
Title: Improved sealing system for chemical apparatus
IPC: F16L49/00
Filed: 1983-11-25
Abstract: Improved sealing system between an enclosure of brittle material and a metal apparatus for carrying out chemical reactions, in which a connection member (6) is mounted over the open end (2') of the enclosure (2), with the interposition of a toroidal seal (9) between the opening into the enclosure and the underside of the connection member; a supplementary toroidal seal (11) is inserted between the lateral exterior wall of the enclosure (2,2') and the bore of the connection member (6).
[US4645648A]
Patent IE-54221-B1 (IE)
Title: (+)-2-(1-(2,6-dichlorophenoxy)-ethyl)-1,3-diazacyclopent-2-ene, the production thereof and the use thereof in pharmaceutical preparations
IPC: C07D233/22
Filed: 1982-11-25
Abstract: This invention relates to (+)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene and to pharmaceutically acceptable acid addition salts thereof and the method for the treatment of human beings suffering from nervous disarrangements, in particular migraine, using these compounds.
Patent IE-58567-B1 (IE)
Title: A rapid method for interrupting the narcotic addiction syndrome
IPC: A61K31/435
Filed: 1984-11-15
Abstract: The administration to a heroin addict of ibogaine, ibogaine HCl or other non toxic salts of ibogaine, an alkaloid of the family apocynaceae, has been discovered to unexpectedly interrupt the physiological and psychological aspects of the opiate addiction syndrome. A single treatment was effective for about 6 months, and a series of 4 treatments was effective for approximately 3 years. The treatments consisted of the oral administration of ibogaine or its salts in dosage ranges of 6 mg/kg to 19 mg/kg. The minimum effective dose was 400 mgs and dosage increases above 1000 mgs were found to be unnecessary. Treatments were effective in 71% of the cases.
Patent IE-63216-B1 (IE)
Title: Production of 2,3'-anthydro-2'-deoxyuridine derivatives
Inventor: REESE COLIN BERNARD
IPC: A61K31/70
Filed: 1988-11-11
Abstract: A process for the production of a 5-substituted derivative of a 2,3 min -anhydro-2 min -deoxyuridine preferably corresponding to the following general formula: <CHEM>  wherein  R<1> represents H, alkyl, aryl, halogeno or CF3; characterised in that it comprises heating a 5-substituted derivative of a 2 min -deoxyuridine preferably corresponding to the following general formula: <CHEM>  wherein R<1> is as defined above; in the presence of a sulphite transfer reagent and preferably a solvent is disclosed. This process improves the production of valuable intermediates and hence facilitates and reduces the cost of production of pharmacologically-interesting compounds.
Patent IE-73263-B1 (IE)
Title: Crosslinkable resin composition comprising a thermoplastic resin
Inventor: KLAIBER ADOLF AUGUST
IPC: D06M101/16
Filed: 1992-07-01
Abstract: A crosslinkable resin composition containing :     (A) from 10% to 90% by weight of a thermoplastic resin component, (B) from 90% to 10% by weight of a curable resin component, comprising, expressed by reference to the curable resin (100%),     (i) 50% to 95% of a (meth)acryloyl derivative, and   (ii) 50% to 5% of a (meth)allyloxy derivative, and   (C) from 0% to 30% by weight of a plasticiser for the thermoplastic resin component,  is disclosed. Also a new crosslinked resin layer and a process for the manufacture of the new crosslinked resin layer on a substrate are described. The crosslinked resin layer herein exhibits a desirable balance between flexibility, resistance to stain and resistance to scuff properties, in combination with outstanding mechanical and chemical properties. The crosslinkable resin composition is particularly suitable for coating application of various substrates such as flooring materials, wall covering materials, coils, wires, and various shaped articles e.g. cars, containers and metallic profiles.
Patent LU-102274-B1 (LU)
Title: Double arch tunnel supporting structure suitable for soft rock condition
Inventor: CHEN CHENG
IPC: E21F11/00
Filed: 2020-12-07
Granted: 2021-06-07
Abstract: The present invention discloses a double arch tunnel supporting structure suitable for a soft rock condition, including a tunnel supporting structure, a middle pilot tunnel cross beam and a middle pilot tunnel cross brace. In the double arch tunnel excavation process, tunnel section supporting structures are sequentially arranged along a tunnel excavation direction, the adjacent two tunnel section supporting structures arc connected through a purline in a direction of the tunnel, the tunnel section supporting structures are connected through the middle pilot tunnel cross beam and the middle pilot tunnel cross brace on the same plane, and the excavation and support work of the tunnel is completed by excavating and supporting; a driving space and a middle pilot tunnel are formed, and the middle pilot tunnel is used to ensure people to avoid risks in time when an accident occurs in the funnel: a section shape of a supporting structure is similar to a shape alter a soil layer under a soft rock geology is excavated, a model may be designed and constructed along with a section shape, thereby reducing filling of a section notch after a building is completed: and under the condition of ensuring the supporting strength, the double arch tunnel supporting structure is simple in structure and convenient to construct, and a construction period is effectively shortened.