baber/WOPTO huggingface dataset:
Patent EA-003142-B1 (EA)
Title: Pharmaceutical composition with an antidepressive effect use thereof and method for treating
Inventor: MAJ JERZY
IPC: A61K31/425
Filed: 1999-07-02
Abstract: 1. A pharmaceutical composition comprising an antidepressive amount of 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole, one of the enantiomers thereof or one of acid addition salts in combination with sertraline or one of pharmaceutically acceptable salts thereof. 2. A pharmaceutical composition in accordance with Claim 1 comprising the (+)-enantiomer of 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole (pramipexole), or one of acid addition salts thereof. 3. A pharmaceutical composition in accordance with Claim 1 comprising the (-)-enantiomer of 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole, or one pharmaceutically acceptable acid salts thereof. 4. A pharmaceutical composition in accordance with any of Claims 1-3 comprising 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole dihydrochloride, first of all, 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole dihydrochloride monohydrate thereof. 5. A pharmaceutical composition in accordance with Claim 1 comprising of 0.05-10 mg of 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole, one of the enantiomers thereof or one of acid addition salts thereof, pramipexole or pramipexole dihydrochloride monohydrate. 6. A pharmaceutical composition in accordance with Claim 1 comprising of 0.088-1.5 mg of 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole, one of the enantiomers thereof or one of acid addition salts thereof, pramipexole or pramipexole dihydrochloride monohydrate. 7. A pharmaceutical composition in accordance with Claim 6 comprising 0.088-1.1 mg of pramipexole, or between 0.125 and 1.5 mg of pramipexole dihydrochloride monohydrate. 8. A pharmaceutical composition in accordance with any of Claims 1-7 comprising between 25 and 200 mg of sertraline. 9. A pharmaceutical composition in accordance with Claim 8 comprising 50 mg of sertraline. 10. The use of compound of any of preceding Claims for treatment of depressions and depression conditions. 11. The use of compound of any of preceding Claims for preparation of medicine for treatment of depressions and depression conditions. 12. A method for treating depressions in patients, suffering from one of such diseases, characterized in that the combination of active substances in accordance with any of preceding Claims is used. 13. A method of Claim 12, characterized in that the active substances in the form of separate compounds are administered in series in accordance with determined temporary scheme.
Patent EA-002917-B1 (EA)
Title: Use of sodium chloride for minimization of secondary of gastro-intestinal effects caused by administration of camptothecin derivatives
Inventor: TOUTAIN HERVE
IPC: A61K33/00
Filed: 1999-08-03
Abstract: 1. The use of sodium chloride for preparation of an agent for minimization or elimination of secondary gastro-intestinal effects, caused by administration of camptothecin derivatives, characterized in that said agent is an aqueous solution of sodium chloride and it is administered orally. 2. The use according Claim 1, characterized in that concentration of sodium chloride solution is from 4 to 13 g/l. 3. The use according Claim 2, characterized in that concentration of sodium chloride solution is 9 g/l. 4. The use according to any of Claims 2 or 3, characterized in that sodium chloride solution is administered in doses from 5 to 10 ml/kg/administration. 5. The use according to any of Claims 1-4, characterized in that sodium chloride solution is administered either during or before and during administration of camptothecin derivative. 6. The use according Claim 1, characterized in that camptothecin derivative is administered by injection or orally.
Patent EA-004973-B1 (EA)
Title: Parallel positioning mechanism, especially for machining and/or manipulation and/or measuring
Inventor: VALASEK MICHAEL
IPC: B23Q1/64
Filed: 2002-06-14
Abstract: 1. Parallel positioning mechanism, especially for machining and/or manipulation and/or measuring, consisting of a platform for the carrying and/or manipulation with, for instance, a tool, a workpiece, a measuring device or the like, wherein the platform is connected with the machine frame by means of at least one positioning arm, characterised in that the platform (3) is joint-connected with at least one sliding guide (4) via at least three rotatable joints (11), wherein each positioning arm (6) is provided with one rotatable joint (11) for the connection with the platform (3) and one rotatable joint (11) for the connection with the sliding guide (4). 2. Parallel positioning mechanism according to claim 1 characterised in that the sliding guide (4) are in mutually intersecting relationship. 3. Parallel positioning mechanism according to claim 1 or 2, characterized in that the platform (3) is joint-connected with a frame (2) via at least one positioning arm (6) for the connection with one sliding guide (4) and further a rotatable joint (11) for the direct connection with the sliding guide (4). 4. Parallel positioning mechanism according to claims 1 to 3, characterized in that the platform (3) is joint-connected with the frame (2) through four positioning arms (6) with at least two sliding guides (4). 5. Parallel positioning mechanism according to claim 4, characterized in that the platform (3) is joint-connected with the frame (2) through four positioning arms (6) with four sliding guides (4). 6. Parallel positioning mechanism according to claims 1 and 2, characterized in that the sliding guides (4) are parallel to at least straight lines. 7. Parallel positioning mechanism according to one of claims 1-6, characterized in that the projections of the axes of rotation of the rotatable joints (11) of the platform (3) into a plane perpendicular to them form a trapezoid. 8. Parallel positioning mechanism according to one of claims 1-7, characterized in that the platform (3) is connected with the sliding guide (4) through positionable carriages (5), which are kinematically connected with driving motors (10) through ball screws (12) with nuts. 9. Parallel positioning mechanism according to one of claims 1-8, characterized in that the platform (3) is connected with the sliding guide (4) through positionable carriages (5) which are connected with a linear drive. 10. Parallel positioning mechanism according to one of claims 1-9, characterized in that the platform (3) is provided with a translatable chuck (8). 11. Parallel positioning mechanism according to one of claims 1-10, characterized in that the base (1) of the machine is arranged slidably with respect to a work support. 12. Parallel positioning mechanism according to one of claims 1-11, characterized in that the sliding guides (4) are arranged in a frame (2) of the machine, which is displaceable with respect to the base (1) of the machine.
Patent EA-007372-B1 (EA)
Title: Method of using electrical and acoustic anisotropy measurements for fracture identification
Inventor: KRIEGHAUSER BERTHOLD
IPC: G01V1/40
Filed: 2002-12-13
Abstract: Measurements made by a cross-dipole acoustic logging tool in a borehole are processed to determine the principal directions of azimuthal anisotropy of a subsurface formation. Measurements such as in data tracks (601, 603) are also made for correlation and comparison purposes of a Gamma Ray Log (621), a Caliper Log (623), a Density Log (631) and a Neutron Porosity Log (633). Measurements indicative of azimuthal resistivity logging variations and conductivity logging variations (605, 607, 609, 611) are also made with a multicomponent induction logging tool that is capable of performing electrical measurements at a number of different frequencies that also covers a range of different downhole depths. These electrical measurements are processed using the principal direction determined from acoustic measurements to give an estimate of azimuthal resistivity variations. Based on modeling results, azimuthal resistivity variations are interpreted to estimate a fracture depth in the rock for known fluids therein.
Patent EA-008835-B1 (EA)
Title: Substituted sulfone and sulfonamides and pharmaceutical compositions based thereon useful for the treatment of obesity, type ii diabetes cns disorders
Inventor: JOHANSSON GARY
IPC: C07D493/04
Filed: 2003-06-19
Abstract: The present invention relates to compounds of the general formula (I), wherein P is sulfone or sulfonamide; and A, B, W, X, Y and Rare as defined in the description; to pharmaceutical compositions comprising these compounds, and to the use of the compounds for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes, and/or CNS disorders, to achieve reduction of body weight and of body weight gain.
Patent EA-007619-B1 (EA)
Title: Film coating for tablets and caplets
Inventor: CADE DOMINIQUE NICOLAS
IPC: A61K9/20
Filed: 2003-07-30
Abstract: The present invention relates to novel coating compositions for application to solid dosage forms such as tablets or caplets, solid dosage forms coated with the composition, and methods of preparing said coating compositions.
Patent EA-010790-B1 (EA)
Title: N-thiazol-2-yl-benzamide derivatives
Inventor: SAMS ANETTE GRAVEN
IPC: A61K31/426
Filed: 2004-10-25
Abstract: The invention relates to N-thiazol-2-yl-benzamide derivatives of the formula I in the description wherein the variables are as defined in the claims. The compounds are A-receptor ligands, such as antagonists, agonists, reverse agonists or partial agonists, and are useful in the treatment of neurological and psychiatric disorders where an A-receptor is implicated.
Patent EA-009155-B1 (EA)
Title: Panel structure
Inventor: BRIDGE IAIN NORMAN
IPC: B29D24/00
Filed: 2004-11-16
Abstract: The invention discloses a panel structure (10) is formed from two sheets (12). The sheets (12) are spaced apart to provide a void (13) between them. The sheets (12) are tied together at various positions (14). The ties (14) are formed of substantially the same material as the sheets (12), in such a way that the sheets (12) and the tie means (14) form an uninterrupted body of material. The ties (14) leave unobstructed voids (13) within the plane of the panel. An elongate reinforcing member (15) is located within one of the voids.
Patent EA-011815-B1 (EA)
Title: Pyrrolopyrazoles, potent kinase inhibitors
Inventor: BOUZIDA DJAMAL
IPC: C07D487/04
Filed: 2005-12-28
Abstract: Pyrrole pyrazole compounds of formula (I), compositions including these compounds and methods of their use are provided. Preferred compounds of formula I have activity as protein kinase inhibitors, including as inhibitors of PAK4.
Patent EA-016539-B1 (EA)
Title: Device for disinfection
Inventor: BERENTSVEIG VLADIMIR
IPC: A61L2/20
Filed: 2006-08-04
Abstract: A nebulant suitable for sterilization comprising finely divided liquid droplets suspended in a gas, said droplets including a solute, which is advantageously hydrogen peroxide and a solvent, for example water, wherein the droplets have a concentration of greater than 60 wt% of solute and an average diameter of less than 1.0 micron, preferably less than 0.8 microns. Sterilization using the nebulant may be carried out in suitably adapted apparatus by nebulising a solution comprising a sterilizing agent in a solvent to form a nebulant of finely divided particles of the solution in a gas stream, said solution including a solvent having a lower boiling point than the sterilizing agent; subjecting the nebulant to energy of a kind and for a duration sufficient to vaporize solvent in preference to sterilizing agent, whereby to increase the concentration of the agent in the nebulant particles; removing the solvent vaporized from the gas stream at or above atmospheric pressure and, if necessary, cooling the nebulant to below 70°C; and exposing a surface to be sterilized to the nebulant of concentrated sterilizing agent for a time sufficient to sterilize the surface.
Patent EA-016639-B1 (EA)
Title: A glass product and a method for manufacturing a glass product
Inventor: RAJALA MARKKU
IPC: C03C17/36
Filed: 2008-12-19
Abstract: A glass product of the present invention (1) comprises a glass substrate (2), a reflective metal layer (3) deposited on the glass substrate, and a passivation layer (4) deposited on the reflective metal layer. According to the present invention, the passivation layer (4) is deposited using an Atomic Layer Deposition (ALD) process.
Patent EA-015412-B1 (EA)
Title: Apparatus for synthesis of carbonic nanostructures
Inventor: BASAEV ALEXANDER SERGEEVICH
IPC: B82B3/00
Filed: 2010-08-23
Abstract: The invention relates to a technology of production carbonic nanostructures and can be used in electronic industry. An apparatus for the synthesis of carbonic nanostructures comprises a reactor 1, a sample holder 2, at least one reactor heater 3. at least one capacity for liquid-phase 4 which provided with a system of controlling reagents 5 discharge, at least one atomizer 6 for injecting the liquid-phase reagent into an evaporator 7, a means for creating a uniform reagent stream in the reactor 8 by its concentration, a system of pressure control and regulation in reactor 9, and, at least one capacity for carrier-gas 10. The sample holder 2 is installed in reactor 1 adapted for linear displacement along the reactor and/or for angular displacement. The system of controlling reagents 5 discharge is also adapted the pressure regulation upon said the liquid-phase reagent by providing an excess gas pressure on the liquid-phase reagent or as a piston. The inventive result is aimed at broadening functional abilities of the apparatus providing wider varying regimes of nanostructures grow in a wide range with sufficient repeatability of results that also ensures ability to grow different types of carbonic nanostructures at one sample.
Patent EA-018728-B1 (EA)
Title: Resilient, water dispersible polyurethane foams and products incorporating same
Inventor: KOKKO BRUCE J
IPC: C08G18/10
Filed: 2008-09-16
Abstract: A soft and resilient, cold water dispersible polyurethane foam suitable for disposable personal care products is produced by the combination of corn syrup, glycerin, polyether diamine, PEG, a diisocyanate, water and a catalyst. The formulation and reaction conditions for forming the inventive foam are judiciously selected and carefully controlled to achieve water dispersibility and the desired mechanical properties. The characteristic resiliency, or percent rebound for the foams was generally over 75% and the foams are readily produced as soft foams, exhibiting a relative compression value of from 20% to 150% of that of a commercial polyurethane foam cosmetic pad which is not water dispersible. The foam may be incorporated into webs or stackable products or nestable three-dimensional products.
Patent EA-021792-B1 (EA)
Title: Orally-disintegrating solid preparation
Inventor: KURASAWA TAKASHI
IPC: A61K31/4439
Filed: 2009-03-10
Abstract: The present invention provides an orally-disintegrating solid preparation such as a tablet produced by tabletting fine granules showing controlled release of a pharmaceutically active ingredient and an additive, and the like, and the orally-disintegrating solid preparation containing fine granules coated with a coating layer containing a polymer affording a casting film having an elongation at break of about 100 to about 700%. With the preparation, breakage of fine granules during tabletting can be suppressed in the production of an orally-disintegrating solid preparation containing fine granules showing controlled release of a pharmaceutically active ingredient.
Patent EA-016338-B1 (EA)
Title: Improved sawing wire spool
Inventor: PAUWELS LUC
IPC: B21C47/28
Filed: 2009-11-10
Abstract: The invention relates to a spool for winding fine metal wire on, comprising a core and two flanges coupled to either end of said core, wherein the outer side of each of said flanges comprises multiple debossed areas that extend radial from said core and are evenly distributed around said core. The debossed areas reduce the spreading of the flanges when winding fine metal wire on.
Patent EA-021907-B1 (EA)
Title: Method for preparing sofc electrolyte
Inventor: BONE ADAM
IPC: H01M8/12
Filed: 2009-04-30
Abstract: The present invention is concerned with methods for the deposition of ceramic films on ceramic or metallic surfaces, particularly the deposition of sub-micron thickness ceramic films such as films of stabilised zirconia and doped ceria such as CGO (cerium gadolinium oxide). The present invention is particularly useful in the manufacture of high and intermediate temperature operating fuel cells including solid oxide fuel cells (SOFC) and also metal supported intermediate temperature SOFC operating in the 450-650°C range.
Patent EA-028837-B1 (EA)
Title: Method and apparatus for handling gases
Inventor: SZENTIVANYI PETER
IPC: F28C3/06
Filed: 2010-11-30
Abstract: The invention relates to an apparatus and a method for handling gases, the apparatus comprising an inlet gas duct (2) leading said gas to a bubbling tank (21), and a gas buffer drum (3) opening into the tank (21) via perforations formed on a plate (3a) of the drum (3), and a suction duct (5) submerged in gas handling liquid (7) situated in the tank (21), and having a gas outlet duct (8) connected into the gas room (3b) of the tank (21). Said perforations formed on the plate (3a) of the drum (3) are shaped as nozzles (4) having a blow direction (J) inclined by an acute angle relating to the plate (3a). The apparatus further comprising a valve (31) for draining the liquid (7) and a turbine house (22) divided into two chambers (22a, 22b) by a plate (27), the first chamber (22a) housing an air turbine (43) driven by a liquid turbine (23) housed in the second chamber (22b) and operated by a liquid jet nozzle (26). The first chamber (22a) is connected to the tank (21) by means of the gas outlet duct (8), and the suction duct (5) is connected to the liquid jet nozzle (26) via pump (29a), and the second chamber (22b) is connected to the tank (21).
Patent EA-033089-B1 (EA)
Title: Method employing pressure transients in hydrocarbon recovery operations
Inventor: PAULSEN JIM-VIKTOR
IPC: E21B43/16
Filed: 2011-06-15
Abstract: The invention relates to methods to induce pressure transients in fluids for use in hydrocarbon recovery operations. The invention is further characterized by inducing the pressure transients in a fluid by a collision process. The collision process employs a moving object (103, 203, 303, 403) that collides outside the fluid with a body (102, 202, 302, 402) that is in contact with the fluid inside a partly enclosed space (101, 201, 301, 401). Furthermore, the pressure transients must be allowed to propagate in the fluid. The fluid may be one or more of the following group: primarily water, consolidation fluid, treatment fluid, cleaning fluid, drilling fluid, fracturing fluid and cement.
Patent EA-030492-B1 (EA)
Title: Roof switch adapted for operation in icing conditions for a rail vehicle
Inventor: QUENTIN NICOLAS
IPC: H01H19/06
Filed: 2014-10-16
Abstract: The invention is related to an electric switch (12) for a rail vehicle, comprising a horizontal base (16), a post (18) disposed above the base and rotatable about the vertical axis relative to the base, a movable contact (43) joined rigidly to the post, and a stationary contact (44) joined rigidly to the base, wherein rotation of the post results in movement of the movable contact (43) between a connection position where it rests on the stationary contact (44), and a disconnection position where it diverges from the stationary contact. Beyond the limits of a radius (33) that is less than or equal to 30 mm, relative to the vertical rotation axis (20), the vertical distance (32) between the post and the base exceeds or is equal to 10 mm.
Patent EA-032984-B1 (EA)
Title: Method for hypothermal peritoneal- enteral sanitation
Inventor: GAMZAEV SADIG MAKHMUD OGLY
IPC: A61M3/02
Filed: 2014-07-11
Abstract: The invention relates to medicine, in particular, to abdominal surgery, and may be used for severe peritonitis and intestinal obstruction treatment. The objective of the invention consists in early recovery of the intestinal peristalsis, restriction of the inflammatory process and reduction of mortality in generalized purulent peritonitis treatment through a maximum detoxication effect. The objective is achieved by way of a sharp decrease in the temperature of a solution used for peritoneal and enteral sanitation. The essence of the invention consists in that in the proposed method for hypothermal peritoneal and enteral sanitation during peritonitis and intestinal obstruction treatment abdominal cavity lavage with antiseptics is provided during the surgery, perinephric region and bowel mesentery are blocked with 5% Novocaine solution, then peritoneal sanitation with a cold saline (t=+3 - +6°C) is conducted 3 times during 10-15 min until clean content flows across the tube, then intestinal decompression is performed using a naso-gastrointestinal tube, after which, in the post-operative period, active hypothermal enteral sanation is conducted within 12, 24, 48 and 72 h period of time until intestinal peristalsis resumes; the anterior abdominal wall shall be iced for 30-40 min every 3 h.
Patent EA-036442-B1 (EA)
Title: Verification of stored data by determination of storage parameters using a distributed database with nonvolatile objects
Inventor: TORMASOV ALEXANDER GENNADIEVICH
IPC: G06F21/62
Filed: 2016-12-13
Abstract: A system and a method, wherein an agreement between a service consumer and a data storage service provider includes the value of the stored data verification parameter. Measurable numeric values which are one of the service levels provided by the verifier are specified in the agreement. The verifier is responsible for compliance of the consumer data with the data of the data storage service. The service consumer uses a Client AWS that redirects and processes service queries of the consumer to proxy. The Client AWS uses a Security Agent responsible for safe use of the service consumer keys. The proxy redirects and processes the queries from the Client AWS to the data storage service, which is a set of data stores.
Patent EA-033075-B1 (EA)
Title: Method for obtaining sulfur nanoparticles from solutions in dimethyl sulfoxide
Inventor: URAKAEV FARIT KHISAMUTDINOVICH
IPC: C01B17/02
Filed: 2017-11-29
Abstract: The invention relates to the field of nanotechnologies, in particular, to obtaining aqueous-organic or organic solutions of sulfur nanoparticles intended for wide practical application. The use of a solution of sulfur in dimethyl sulfoxide saturated at room temperature, with a sulfur concentration of at least 1.592 g/l, as a precursor, and dilution with water 10-1,000 fold or with acetone 50-1,000 fold results in formation and dimensional stabilization of sulfur nanoparticles in the solution. The technical result: obtaining aqueous-organic solutions of sulfur nanoparticles with a size of 63-130 nm and dimensional stabilization time of 70-108 min; organic solutions of sulfur nanoparticles with a size of 59.5-180 nm and dimensional stabilization time of 14-51 min.
Patent EA-039885-B1 (EA)
Title: 6-amino-7-bicyclo-7-deaza-purine derivatives as protein kinase inhibitors
Inventor: BUFFA LAURA
Filed: 2015-11-12
Abstract: The invention relates to 6-amino-7-bicyclo-7-deaza-purine derivatives of formula (I) which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular RET family kinases. The invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds and uses of these compounds.