baber/WOPTO huggingface dataset:
Patent NZ-337791-A (NZ)
Title: Recombinant forms of Haemopoietic growth factor for use in the treatment of cancers and inflammation
Inventor: VADAS MATHEW ALEXANDER
IPC: A61P35/02
Filed: 1996-06-21
Abstract: The Haemopoietic Growth Factor (HGF) antagonists, E21K and E21R, carry a substitution of amino acid 21 (Glu) of human GM-CSF, by Arg or Lys or any other basic or non-acidic amino acid residue. These antagonists bind to an HGF-specific alpha chain and a beta-c chain of the HGF heterodimeric receptor.  The HGF antagonists induce apoptosis in cells carrying this receptor, and may be used in the treatment of cancers, such as myeloid leukaemias, inflammation, such as rheumatoid arthritis, and allergic conditions such as asthma.   Divided out of 310366
Patent NZ-503098-A (NZ)
Title: Expression systems utilising the CH2-CH3 region of human immunoglobulin to target production of recombinant antibodies in avian eggs
Inventor: ETCHES ROBERT J
IPC: C12N5/10
Filed: 1998-08-21
Abstract: An expression system for producing an antibody comprises a DNA sequence encoding a human immunoglobin heavy chain region and a regulatory region sufficient to provide expression of the antibody. The immunoglobin heavy chain region can bind to an avian egg and be internalized into yolk. The expression system may further comprise a DNA sequence encoding a human immunoglobin variable region. The antibody can be produced by introducing the expression system into an egg-laying animal, obtaining an egg containing the antibody and then the antibody can be isolated from the egg. Also disclosed is a transformed avian cell line that secretes the recombinant antibody and a transgenic egg-laying animal whose cells contain the expression system.
Patent NZ-504488-A (NZ)
Title: Support for an electrical contact arrangement
Inventor: MOSSNER FRANK
IPC: H01R13/514
Filed: 1999-01-21
Abstract: The invention relates to a support (1) for an electrical contact arrangement, comprising an electrically non-conductive base body with electrical contacts (3) arranged therein. The support (1) has a modular design consisting of individual elements which can be assembled (2, 4). The individual elements (2) are provided with or without contacts (3).
Patent NZ-506787-A (NZ)
Title: Trisubstituted 1,3,5-triazine derivatives having HIV replication inhibiting properties for treatment of HIV infections and preparation process thereof
Inventor: DE JONGE MARC RENE
IPC: A61P31/18
Filed: 1999-03-24
Abstract: The use of a compound of formula (I) a N-oxide, a pharmaceutically acceptable addition salt or a stereochemically isomeric form thereof, for the manufacture of a medicine for the treatment of HIV (Human Immunodeficiency Virus) infection, wherein: A is CH, CR4 or N; n is 0,1,2,3 or 4; R1 and R2 are hydrogen, hydroxy, C1-12alkyl, C1-12alkyloxy, C1-12alkylcarbonyl, C1-12alkyloxycarbonyl, aryl, amino, mono-or di (C1-12alkyl)amino, mono-or di (C1-12alkyl) aminocarbonyl wherein each of the aforementioned C1-12alkyl groups may optionally and each individually be substituted with one or two substituents each independently selected from hydroxy, C1-6alkyloxy, hydroxy C1-6alkyloxy, carboxyl, C1-6alkyloxycarbonyl, cyano, amino, imino, aminocarbonyl, aminocarbonylamino, mono-or di (C1-6alkyl)amino, aryl and Het; or R1 and R2 taken together may form pyrrolidinyl, piperidinyl, morpholinyl, azido or mono-or di (C1-12alkyl) aminoC1-4alkylidene; R3 is hydrogen, aryl, C1-6alkylcarbonyl, C1-6alkyl, C1-6alkyloxycarbonyl, C1-6alkyl substituted with C1-6alkyloxycarbonyl; and each R4 independently is hydroxy, halo, C1-6alkyl, C1-6alkyloxy, cyano, aminocarbonyl, nitro, amino, trihalomethyl or trihalomethyloxy ; L is-X-R5 or-X-Alk-R6; wherein R5 and R6 each independently are indanyl, indolyl or phenyl; each of said indanyl, indolyl or phenyl may be substituted with one, two, three, four or five substituents each independently selected from halo, C1-6alkyl, C1-6alkyloxy, hydroxy, C1-6alkylcarbonyl, C1-6alkyloxycarbonyl, formyl, cyano, nitro, amino and trifluoromethyl; Alk is C1-4alkylene; and X is-NR3-,-NH-NH-,-N=N-,-O-,-S-,-S (=O)-or-S (=O) 2-; aryl is phenyl or phenyl substituted with one, two, three, four or five substituents each independently selected from halo, C1-6alkyl, C1-6alkyloxy, cyano, nitro and trifluoromethyl; Het is an aliphatic or aromatic heterocyclic radical; said aliphatic heterocyclic radical is selected from pyrrolidinyl, piperidinyl, homopiperidinyl, piperazinyl, morpholinyl, tetrahydrofuranyl and tetrahydrothienyl wherein each of said aliphatic heterocyclic radical may optionally be substituted with an oxo group; and said aromatic heterocyclic radical is selected from pyrrolyl, furanyl, thienyl, pyridinyl, pyrimidinyl, pyrazinyl and pyridazinyl wherein each of said aromatic heterocyclic radical may optionally be substituted with hydroxy.
Patent NZ-511844-A (NZ)
Title: A cartridge dispensing gun
Inventor: GREENHILL SILVIU
IPC: F16N3/12
Filed: 1999-10-25
Abstract: A manually operably cartridge dispensing gun (1) for cartridges of the kind containing two components.  The gun includes a bed (2) to captively retain the cartridge and a manually operable drive assembly to advance inner (4) and outer (5) concentrically arrranged piston pushers against corresponding pistons in the cartridge.  The outer piston pusher (5) is dimensioned to bear against a circumferentially outermost piston in the cartridge and includes a central aperture to accomodate the inner piston pusher (4) of a first dimension for use with an inner piston of a cartridge having a first component ratio.  The inner piston pusher (4) is selectively reconfigurable to a second, reduced, dimension for use with an inner piston of a cartridge having a second component ratio.
Patent NZ-514076-A (NZ)
Title: Airship/spacecraft with gas for propulsion stored in chamber(s) that can change shape
Inventor: PROVITOLA ANTHONY I
IPC: B64B1/58
Filed: 2000-04-11
Abstract: An airship/spacecraft is disclosed, which, in a preferred embodiment, uses its lifting gas (64) as fuel for thrusters, which may be of the turbo-type or rocket type, or both, to achieve transition to space flight. The airship aspect has gas retaining structures (61) that can withstand internal and external pressure and can change in volume and shape. The gas retaining structures (61) may be compartmentalized with a folded diaphragm membrane (63) and also configured as pressure vessels. The spacecraft aspect provides control, power, services, and space for missions of the airship/spacecraft. The best mode includes a turbo-rocket thruster in which the turbine compressor is used to intake and compress a gaseous fuel for combustion with a stored oxidizer injected into the compressed gaseous fuel stream. The compressor stage (not shown) is driven by the turbine stage (not shown), which is driven by burning gaseous fuel passing across the turbine blades (not shown). The burned gases are then expanded through an exhaust nozzle and thereby ejected to produce reaction thrust.
Patent NZ-514374-A (NZ)
Title: Methods and compounds for sensitising/desensitising a receptor selected from a B cell receptors (BCR), pro-BCR, pre-BCR, immunoglobulin FcR and NK cell receptor
Inventor: VILEN BARBARA J
IPC: C07K16/28
Filed: 2000-02-25
Abstract: Particular members of the multisubunit immune recognition receptor (MIRR) family of receptors, specifically, the B cell antigen receptor (BCR), the pre-B cell receptor (pre-BCR), the pro-B cell receptor (pro-BCR), Ig Fc receptors (FcR), and NK receptors, can be physically uncoupled from their associated transducers. Described are regulatory compounds and methods for mimicking such dissociation/destabilisation for the purposes of receptor desensitisation and for treatment of conditions in which receptor desensitisation or alternatively, enhanced or prolonged receptor sensitisation, is desirable. Compounds and methods for enhancing or prolonging receptor sensitisation are also disclosed, as are methods for identifying regulatory compounds suitable for use in the present methods.
Patent NZ-515541-A (NZ)
Title: Pharmaceutical compositions comprising bisphosphonates to treat angiogenesis
Inventor: OKUNO TETSUJI
IPC: A61K31/675
Filed: 2000-05-19
Abstract: The  use of a bisphosphonate in the preparation  of  a medicament  for the treatment of angiogenesis in  a  patient in  need  of  such  treatment, e.g. a tumour  patient  or  a patient   suffering  from  an  inflammatory  disease.    The treatment  may  comprise administering,  preferably  via  an intra-arterial   route,   an   effective   amount    of    a bisphosphonate, e.g. pamidronic acid or zoledronic  acid  or salts or hydrates thereof, to the patient
Patent NZ-516530-A (NZ)
Title: Mortar grouting type joint for reinforcing bars
Inventor: ABUKAWA MASAHIRO
IPC: E04C5/16
Filed: 2000-06-30
Abstract: A mortar-filled type reinforcing bar joint comprising a hollow sleeve that has open lids (2) at the ends, bolt holes (8) in the side wall, and support projections (5) on the inner wall surface, with reinforcing bars (12) supported by bolts (13) and support projections, wherein the support projection is composed of a pair of thin pieces extending in parallel with each other longitudinally of the hollow sleeve and is so constructed as to have an apex located in a portion at which the thin pieces support the reinforcing bar inserted through the open lid and a ridge (7) sloping downward toward the open lids to form hems, whereby the inserted reinforcing bar can be positioned coaxial with the joint and automatically guided; thus the mortar-filled type reinforcing bar joint is suitable for use when a number of sets of reinforcing bars are to be bare-connected as in the case of joining for reinforcing bar cages.
Patent NZ-524408-A (NZ)
Title: Pharmaceutical composition for inhibiting premature rupture of fetal membranes, ripening of uterine cervix and preterm labor in mammals
Inventor: LEIBOVITZ SHAMIR
IPC: A61K31/195
Filed: 1998-11-24
Abstract: A pharmaceutical composition for treating or preventing premature rapture of the fetal membranes, ripening of the uterine cervix and preterm labor of female mammals including human is disclosed, wherein the pharmaceutical composition comprises a therapeutically effective amount of N-acety cysteine and a pharmaceutically acceptable carrier. The pharmaceutical composition may further comprise an anticytokine antibody or a cytokine carrier, progesterone a progesterone receptor agonist and an estrogen receptor antagonist, a nitrovasodilator, a prostaglandin receptor antagonist, oxyticinase and an oxytocin receptor antagonist. (62) Divided out of 504406
Patent NZ-525117-A (NZ)
Title: Vaccine composition stabilised by addition of high-molecular-weight polyvinylpyrrolidone, in particular PVF360 whose molecular weight is 360 000 daltons
Inventor: FRANCON ALAIN
IPC: A61P37/04
Filed: 2001-10-08
Abstract: Described is the stabilisation of a vaccine composition maintained in liquid state by the use of high molecular weight polyvinylpyrrolidone of a molecular weight greater than or equal to 100,000, hence eliminating the use of albumin. This feature is of particular interest for vaccine compositions comprising attenuated live viruses such as the oral vaccine against poliomyelitis.
Patent NZ-526216-A (NZ)
Title: Selective glucocorticoid receptor agonists
Inventor: BARR STEPHEN ALEXANDER
IPC: C07J41/00
Filed: 2001-11-02
Abstract: Disclosed herein is a method for treating an inflammatory condition, treating haematological and other malignancies, causing immunosuppression, or preventing or treating transplant rejection in animals which comprises administering to a non-human patient a compound that has the structure of formula (I) or formula (II) as defined in the specification, or a pharmaceutically acceptable derivative thereof or pro-drug thereof, wherein R=NH2, NHR1, NHOR2, NHNHR2, NHCOR2, and R1=C(1-4)alkyl, C(3-6)cycloalkyl, or as defined in the specification, R2=methyl, ethyl, R3=alkyl, cycloalkyl, substituted alkyl, substituted cycloalkyl, aryl, heteroaryl, substituted aryl, or substituted heteroaryl; wherein R4, R5=C(1-4)alkyl. Compounds of formula (III), wherein R6 and R7 are any of H, CH3CO, CH3CH2CO, CH3CH2CH2CO provided that R6 and R7 are not both H, or formula (IV), wherein R8 and R9 are any of H, CH3CO, CH3CH2CO or CH3CH2CH2CO, having use in such methods, are also described.
Patent NZ-531774-A (NZ)
Title: Edible pesticidal formulations
Inventor: FLYNN ANTHONY GERARD
IPC: A01N57/10
Filed: 2002-08-16
Abstract: A granular edible pesticidal composition is disclosed, which comprises: (a) a continuous hydrophilic matrix phase comprising hydrophilic material such as cereal grains, blood and bone, peat and animal manure, preferably in particulate form and water, said matrix phase being palatable to pests; and (b) a discontinuous oleophilic phase dispersed within the hydrophilic matrix phase and comprising an oleophilic carrier and pesticide preferably dissolved in the oleophilic phase.
Patent NZ-534943-A (NZ)
Title: Apparatus and process for forming plastic laminated panels, typically for modular building panels
Inventor: BERGQVIST TONNY
IPC: B29C44/58
Filed: 2003-01-31
Abstract: An apparatus is disclosed for manufacture of foamed plastics laminated panels having; an array of press modules, each comprising; a pair of opposed spaced frame members movable relative to one another; adjustment means to adjust spacing between said frame members; hinge to allow a first frame member to move relative to a second frame member; clamp to retain, in use, said frame members in a predetermined spaced relationship, two outer skin layers, in use, are spaced and located on the opposing inner surfaces of the respective frame members; sealing members locatable, in use, between said frame members and two outer skin layers, to define a mould cavity between said opposed outer skin layers when said clamp is actuated, at least one inlet to introduce into said mould cavity a liquid foamable plastics material: respective reservoirs of liquid reactants, for producing a foamable plastic; and delivery means to deliver liquid reactants in predetermined proportions to respective mould cavities. The apparatus is stated to provide a method for producing laminated panels at high volume than currently available. The application also discloses a sleeve for connecting an elongated nozzle extensions (25) to an injection gun comprising an outer U shaped sleeve (22) having an aperture in its base to accommodate nozzle (23) on an injection gun; an inner tubular sleeve (24) screws onto the nozzle (23) and elongated delivery nozzle (25) containing a static mixer (26), engaged with an inner screw thread of the tubular sleeve (24).
Patent NZ-535394-A (NZ)
Title: Dimmer circuit with improved ripple control
Inventor: VANDERZON JAMES ROBERT
IPC: H05B47/10
Filed: 2003-03-25
Abstract: A dimmer circuit arrangement is disclosed including a second control circuit for controlling the operation of a triac for delivering current to a load, and a first control circuit for controlling the operation of an IGBT power semiconductor switch for controlling the rate of rise of load voltage. The first control circuit also controls the operation of the second control circuit.
Patent NZ-535883-A (NZ)
Title: Process for 5-[[2(R)-[1(R)-[3,5-bis(trifluoromethyl)phenyl] ethoxy]-3(S)-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one
Inventor: HUFFMAN MARK
IPC: C07D413/06
Filed: 2003-04-17
Abstract: Disclosed is a process for the preparation of the compound 5-[[2(R)-[1(R)-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one. This compound is useful as a substance P (neurokinin-1) receptor antagonist. In particular, the compound is useful e.g., in the treatment of psychiatric disorders, inflammatory diseases and emesis.
Patent NZ-537680-A (NZ)
Title: System of hysteroscopic insemination
Inventor: MORRIS LEE H
IPC: A61D19/02
Filed: 2001-01-24
Abstract: A method of producing a non-human mammal comprising the steps of: a. collecting sperm cells from a male of a species of non-human mammal; b. establishing an artificial insemination sample utilizing at least some of said sperm cells; c. placing the artificial insemination sample in a catheter; d. determining a time when a female of said species of said non-human mammal is appropriately fertile; e. vaginally inserting an optical element into the female; f. vaginally inserting the catheter into the female; g. guiding the optical and the catheter through the vagina of the female; h. optically locating a uterotubal junction within the female; i. inserting the catheter under a surface in the vicinity of the uterotubal junction within the female; j. extruding at least a portion of the artificial insemination sample from the catheter under the surface in the vicinity of the uterotubal junction with the female; k. depositing at least a portion of said artificial insemination sample under the surface in the vicinity of the uterotubal junction within the female; l. withdrawing the optical element and the catheter from the female; m. allowing fertilization of an egg of the female; n. allowing production of an offspring of the non-human mammal from the fertilized egg.
Patent NZ-544040-A (NZ)
Title: Composition comprising a PDE4 inhibitor and a PDE5 inhibitor
Inventor: DUNKERN TORSTEN
IPC: A61P9/04
Filed: 2004-05-19
Abstract: Disclosed is the use of a combination of a phosphodiesterase 4 (PDE4) inhibitor and a phosphodiesterase 5 (PDE5) inhibitor for the preparation of a medicament for preventing or reducing the onset of chronic obstructive pulmonary disease (COPD), or treating or reducing the severity of COPD, wherein the PDE4 inhibitor is selected from Roflumilast, Roflumilast-N-oxide and the pharmaceutically acceptable salts thereof and the PDE5 inhibitor is selected from the group consisting of Sildenafil, Tadalafil, Vardenafil and the pharmaceutically acceptable salts thereof.
Patent NZ-544688-A (NZ)
Title: Link for the connection of rods of a conveyor belt spirally wound around a driven drum, conveyor belt and conveying system with such connective links
Inventor: FAASSEN WILLEM VAN
IPC: B65G17/06
Filed: 2004-07-02
Abstract: A connective link (4) for a conveyor belt and conveyor belt formed by a series of the links are disclosed. The link has legs (6) extending in a longitudinal direction from a lateral cross-member (7) at a closed first end (8) to an open second end (9). Each of the legs (6) has laterally aligned first apertures (10) on at the closed end (8) for reception of a rod (3), and additional laterally aligned second apertures (11) at the open end (9) for reception of the rod (3) received in the first apertures of an adjoining link. At least one leg (6) is extended in longitudinal direction over a distance from the second aperture (11).
Patent NZ-545257-A (NZ)
Title: A voltage block device and an electrostatic coating system with the voltage block device
Inventor: YOSHIDA YASUSHI
IPC: B05B5/16
Filed: 2004-08-12
Abstract: A voltage block device in an electrostatic coating system for preventing the negative electric potential from being transferred to the coating material source, with a switching device including a slider which is selectively slidable between first and second positions and has an inlet port fluidly communicating with the coating material source and an outlet port fluidly communicating with the spray device, a reservoir including first and second chambers, the inlet and outlet ports fluidly communicating with the first and second chambers respectively when the slider is at the first position, and the inlet and outlet ports fluidly communicating with the second and first chambers respectively when the slider is at the second position.
Patent NZ-545703-A (NZ)
Title: Information recording medium, recording device and recording method for information recording medium, reproduction device and reproduction method for information recording medium, computer program for recording or reproduction, and data structure containing control signal
Inventor: YOSHIDA MASAYOSHI
IPC: G11B7/00
Filed: 2004-07-22
Abstract: A recording apparatus for recording record data onto an information recording medium is disclosed, which comprises: (i) a data area for recording therein the record data; (ii) a plurality of temporary defect management areas for temporarily recording therein defect management information in the data area; and (iii) a flag area for recording therein distinction information for distinguishing a temporary defect management area in which the defect management information that is effective is recorded, from the plurality of temporary defect management areas, where the flag area is divided into a plurality of flag unit areas, and a combination of a recorded condition and an unrecorded condition of the plurality of flag unit areas indicates the distinction information, The recording apparatus comprises: (a) a first recording device for recording the record data into the data area; (b) a second recording device for recording the defect management information into any one of the plurality of temporary defect management areas; (c) a distinction information generating device for generating the distinction information on the basis of the recorded condition and the unrecorded condition of the plurality of temporary defect management areas; and (d) a third recording device for recording the distinction information generated by the distinction information generating device into the flag area.
Patent NZ-549087-A (NZ)
Title: Primer composition for promoting adhesion of polyurethane adhesives and sealants to plastics and paints
Inventor: KULLING ANNEMARIE
Filed: 2006-08-09
Abstract: Disclosed is a primer composition comprising at least one binder which contains isocyanate groups and is prepared from a mixture of an amorphous polyester resin A which is solid at room temperature and contains at least one OH group and of at least one polyisocyanate B of the formula (I), the solid polyester resin A and the polyisocyanate B being used in a ratio such that the stoichiometric ratio of the NCO groups to the OH groups is situated in the range between 50:1 and 100:1 and/or the weight ratio of polyester resin A to polyisocyanate B has a value of between 1.6 and 0.75, in particular between 1.2 and 0.8. These primer compositions are notable in particular for effective adhesion to plastics and paints, especially automobile paints.
Patent NZ-553861-A (NZ)
Title: Computerized process for differential incentives based on payment modes
Inventor: AGARWAL SANJIV
Filed: 2005-08-10
Abstract: A method and system for awarding incentives based on payment modes is provided. The method includes the steps of enrolling customer's through a computer network into a reward program, then, as a customer pays for a purchase, determining a reward incentive based on the method of payment used by the customer, the reward incentive being higher is the payment is in cash than other reward incentives for other such payment methods as cheque or bank card.
Patent NZ-587322-A (NZ)
Title: Hepatitis c virus inhibitors
Inventor: BACHAND CAROL
IPC: C07D491/044
Filed: 2009-02-06
Abstract: The disclosure relates to imidazol-pyrrolidine derivative compounds of structure (I) and their compositions which are suitable for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.